d101ma__d3a5ga___1	Metazoa	Metazoa	Chordata	Arthropoda	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d102la__d1qsqa___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d102la__d2f2na___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d102ma__d1f5pb___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d104lb__d1l98a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d107la__d3txfa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d10gsa2_d6gsxb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d10gsb1_d3qaga2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d10gsb2_d2x64b1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	transferase activity [GO:0016740]
d113la__d119la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d113la__d4n8za___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d118la__d1dyca___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d11gsa1_d5aivc2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d11gsa2_d5a5kw1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d11gsb1_d2x64a2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	transferase activity [GO:0016740]
d11gsb2_d2cvdd2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d122la__d1j92c___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]	
d126la__d3emsa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d12e8h1_d1a7qh1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d12e8l2_d2ht2d1__1		Metazoa		Chordata								
d12e8m1_d1fg2k___1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d12e8m2_d1fskl2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d12e8p1_d3c5zf2__1		Metazoa		Chordata		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d12gsa1_d4gsnd2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	transferase activity [GO:0016740]
d12gsa2_d3vi7d1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d130la__d4lfpa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d131la__d1sfba___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d131la__d3g3xa___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d134la__d1xgtc___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d135la__d1lyha___1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d137la__d1z55a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d137lb__d4i8sa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d138la__d4w55a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d13gsa1_d2f8fa1__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d13gsa1_d5agyb2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d13gsb1_d4q5qa2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d140la__d1j92a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]	
d141la__d2ydga___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d141la__d3huqa___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d142la__d1gf4a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d146la__d1b5xa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d147la__d1o23a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	host cell cytoplasm [GO:0030430]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	lysozyme activity [GO:0003796]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d148le__d1lyda___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d150lb__d2ntha___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d154la__d3gxkb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]		lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d155la__d2b73a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d159la__d3kama___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d15c8h1_d1qygh1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d15c8l1_d4pd4k___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d15c8l2_d5i0zb___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d166la__d1tcya___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d167la__d2lzha___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d168la__d4dc4c___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d168lc__d1hfya___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; lactose biosynthetic process [GO:0005989]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	lactose biosynthetic process [GO:0005989]	host cell cytoplasm [GO:0030430]	extracellular region [GO:0005576]	lysozyme activity [GO:0003796]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]
d168le__d2oe7x___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d169ld__d4lt2a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d16gsa1_d3i6aa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d170la__d5jgxa___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d172la__d180lb___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d172la__d2i25l___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d173la__d1bwia___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d174lb__d1yqvy___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d175lb__d4phic___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d176la__d1iora___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d176la__d1l40a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d176lb__d1wqpa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d178la__d2b6xa___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d17gsa2_d2gsrb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d17gsb1_d3wd6b2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d17gsb2_d5k2jj1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d184la__d216la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d187la__d4dwxa___1		Viridiplantae		Streptophyta	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]; polysaccharide catabolic process [GO:0000272]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]; polysaccharide catabolic process [GO:0000272]	host cell cytoplasm [GO:0030430]	extracellular region [GO:0005576]	lysozyme activity [GO:0003796]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d189la__d2lcba___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d18gsa2_d5ld0a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d18gsb2_d5ecif1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d195la__d4lt0a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d19gsa2_d3i43a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]
d19gsb1_d4edya2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d19hca__d2yxca___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]		anaerobic respiration [GO:0009061]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1a00d__d2uulh___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1a04b2_d3lteo___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; nitrate assimilation [GO:0042128]; phosphorelay signal transduction system [GO:0000160]; regulation of gene expression [GO:0010468]; regulation of nitrate assimilation [GO:0090352]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	nitrate assimilation [GO:0042128]; phosphorelay signal transduction system [GO:0000160]; regulation of gene expression [GO:0010468]; regulation of nitrate assimilation [GO:0090352]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding [GO:0003677]
d1a05a__d3blxi___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial isocitrate dehydrogenase complex (NAD+) [GO:0005962]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; isocitrate dehydrogenase (NAD+) activity [GO:0004449]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; RNA binding [GO:0003723]; glutamate biosynthetic process [GO:0006537]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	glutamate biosynthetic process [GO:0006537]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial isocitrate dehydrogenase complex (NAD+) [GO:0005962]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NAD+) activity [GO:0004449]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; RNA binding [GO:0003723]
d1a0ca__d5nhda___1		Fungi	Firmicutes	Chytridiomycota	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d1a0cd__d4xkmc___1			Firmicutes	Bacteroidetes	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1a0fb1_d5u56d2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; response to hydrogen peroxide [GO:0042542]		response to hydrogen peroxide [GO:0042542]		cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]	
d1a0fb2_d2on7a1__1			Proteobacteria		cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; response to hydrogen peroxide [GO:0042542]		response to hydrogen peroxide [GO:0042542]		cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]	
d1a0ja__d5b6ob___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	digestion [GO:0007586]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1a0jc__d1wqvh___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	digestion [GO:0007586]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d1a0lb__d5etxb1__1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; transformation of host cell by virus [GO:0019087]	proteolysis [GO:0006508]	transformation of host cell by virus [GO:0019087]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]		serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d1a0ld__d1v2jt___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1a0oa__d2jrla___1			Proteobacteria	Aquificae	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d1a0og__d3hv2b___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	
d1a0ql1_d1x9qa1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1a0ql2_d1tpxc2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d1a0ua__d2zfoc___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1a0uc__d1habb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1a0ud__d5hu6a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1a0va__d3d1ka___1		Metazoa		Chordata		hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1a0vb__d1habd___1		Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1a0za__d2uula___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1a10i__d1y3fi1__1				Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1a12b__d3qhyb___1	Metazoa		Chordata	Actinobacteria	chromatin [GO:0000785]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; nucleosomal DNA binding [GO:0031492]; nucleosome binding [GO:0031491]; protein heterodimerization activity [GO:0046982]; Ran GTPase binding [GO:0008536]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]; sulfate binding [GO:0043199]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic spindle organization [GO:0007052]; protein heterotetramerization [GO:0051290]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]; viral process [GO:0016032]	metal ion binding [GO:0046872]	cell division [GO:0051301]; chromosome segregation [GO:0007059]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic spindle organization [GO:0007052]; protein heterotetramerization [GO:0051290]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]; viral process [GO:0016032]		chromatin [GO:0000785]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		chromatin binding [GO:0003682]; histone binding [GO:0042393]; nucleosomal DNA binding [GO:0031492]; nucleosome binding [GO:0031491]; protein heterodimerization activity [GO:0046982]; Ran GTPase binding [GO:0008536]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]; sulfate binding [GO:0043199]	metal ion binding [GO:0046872]
d1a12c__d3qi0b___1	Metazoa		Chordata	Actinobacteria	chromatin [GO:0000785]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; nucleosomal DNA binding [GO:0031492]; nucleosome binding [GO:0031491]; protein heterodimerization activity [GO:0046982]; Ran GTPase binding [GO:0008536]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]; sulfate binding [GO:0043199]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic spindle organization [GO:0007052]; protein heterotetramerization [GO:0051290]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]; viral process [GO:0016032]	metal ion binding [GO:0046872]	cell division [GO:0051301]; chromosome segregation [GO:0007059]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic spindle organization [GO:0007052]; protein heterotetramerization [GO:0051290]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]; viral process [GO:0016032]		chromatin [GO:0000785]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		chromatin binding [GO:0003682]; histone binding [GO:0042393]; nucleosomal DNA binding [GO:0031492]; nucleosome binding [GO:0031491]; protein heterodimerization activity [GO:0046982]; Ran GTPase binding [GO:0008536]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]; sulfate binding [GO:0043199]	metal ion binding [GO:0046872]
d1a14l__d2q76a2__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1a19b__d1b2sf___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1a1ba__d1luma1__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cell-cell junction [GO:0005911]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; activation of phospholipase C activity [GO:0007202]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cytokine production [GO:0001816]; interferon-gamma production [GO:0032609]; interleukin-4 production [GO:0032633]; intracellular signal transduction [GO:0035556]; NK T cell differentiation [GO:0001865]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; T cell receptor signaling pathway [GO:0050852]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	activation of phospholipase C activity [GO:0007202]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cytokine production [GO:0001816]; interferon-gamma production [GO:0032609]; interleukin-4 production [GO:0032633]; intracellular signal transduction [GO:0035556]; NK T cell differentiation [GO:0001865]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; T cell receptor signaling pathway [GO:0050852]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	cell-cell junction [GO:0005911]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]
d1a1ca__d2ge9a___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein tyrosine kinase activity [GO:0004713]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; B cell affinity maturation [GO:0002344]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; cell maturation [GO:0048469]; cellular response to interleukin-7 [GO:0098761]; cellular response to molecule of fungal origin [GO:0071226]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; histamine secretion by mast cell [GO:0002553]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; mesoderm development [GO:0007498]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cytokine production [GO:0001818]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type III hypersensitivity [GO:0001805]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of B cell apoptotic process [GO:0002902]; regulation of B cell cytokine production [GO:0002721]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; B cell affinity maturation [GO:0002344]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; cell maturation [GO:0048469]; cellular response to interleukin-7 [GO:0098761]; cellular response to molecule of fungal origin [GO:0071226]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; histamine secretion by mast cell [GO:0002553]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; mesoderm development [GO:0007498]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cytokine production [GO:0001818]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type III hypersensitivity [GO:0001805]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of B cell apoptotic process [GO:0002902]; regulation of B cell cytokine production [GO:0002721]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein tyrosine kinase activity [GO:0004713]
d1a1ma1_d4ydkl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d1a1mb__d1jnhc2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	plasma membrane [GO:0005886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1a1na1_d4s11a1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1a1na2_d1lnub2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d1a1oa1_d5ja8b1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1a1oa2_d4p5ma1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d1a1r.1_d1dy9.1__1					cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1a1za__d1n3ka___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	cytosol [GO:0005829]; nucleus [GO:0005634]; apoptotic process [GO:0006915]; carbohydrate transport [GO:0008643]; DNA damage checkpoint [GO:0000077]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glucose import [GO:0046325]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	apoptotic process [GO:0006915]; carbohydrate transport [GO:0008643]; DNA damage checkpoint [GO:0000077]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glucose import [GO:0046325]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	cytosol [GO:0005829]; nucleus [GO:0005634]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	
d1a23a__d5b8af___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]; activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]
d1a25b__d3fdwb___1	Metazoa	Metazoa	Chordata	Chordata	brush border membrane [GO:0031526]; centrosome [GO:0005813]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; androgen receptor binding [GO:0050681]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; histone kinase activity (H3-T6 specific) [GO:0035403]; nuclear receptor transcription coactivator activity [GO:0030374]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell activation [GO:0042113]; B cell receptor signaling pathway [GO:0050853]; dibenzo-p-dioxin metabolic process [GO:0018894]; histone H3-T6 phosphorylation [GO:0035408]; intracellular signal transduction [GO:0035556]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of odontogenesis of dentin-containing tooth [GO:0042488]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of dopamine secretion [GO:0014059]; regulation of glucose transmembrane transport [GO:0010827]; regulation of growth [GO:0040008]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to vitamin D [GO:0033280]	endosome [GO:0005768]; exocytic vesicle [GO:0070382]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; transport vesicle membrane [GO:0030658]; metal ion binding [GO:0046872]; neurexin family protein binding [GO:0042043]; phospholipid binding [GO:0005543]; Rab GTPase binding [GO:0017137]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; multivesicular body sorting pathway [GO:0071985]; negative regulation of insulin secretion [GO:0046676]; plasma membrane repair [GO:0001778]; platelet degranulation [GO:0002576]; positive regulation of exocytosis [GO:0045921]; positive regulation of protein secretion [GO:0050714]; regulation of plasma membrane repair [GO:1905684]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell activation [GO:0042113]; B cell receptor signaling pathway [GO:0050853]; dibenzo-p-dioxin metabolic process [GO:0018894]; histone H3-T6 phosphorylation [GO:0035408]; intracellular signal transduction [GO:0035556]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of odontogenesis of dentin-containing tooth [GO:0042488]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of dopamine secretion [GO:0014059]; regulation of glucose transmembrane transport [GO:0010827]; regulation of growth [GO:0040008]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to vitamin D [GO:0033280]	intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; multivesicular body sorting pathway [GO:0071985]; negative regulation of insulin secretion [GO:0046676]; plasma membrane repair [GO:0001778]; platelet degranulation [GO:0002576]; positive regulation of exocytosis [GO:0045921]; positive regulation of protein secretion [GO:0050714]; regulation of plasma membrane repair [GO:1905684]	brush border membrane [GO:0031526]; centrosome [GO:0005813]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	endosome [GO:0005768]; exocytic vesicle [GO:0070382]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; transport vesicle membrane [GO:0030658]	androgen receptor binding [GO:0050681]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; histone kinase activity (H3-T6 specific) [GO:0035403]; nuclear receptor transcription coactivator activity [GO:0030374]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; neurexin family protein binding [GO:0042043]; phospholipid binding [GO:0005543]; Rab GTPase binding [GO:0017137]
d1a27a__d5bsfc1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]; estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	cell wall [GO:0005618]; nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]; L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]	estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell wall [GO:0005618]	catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]	nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1a27a__d5l7wa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]; estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	cytosol [GO:0005829]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]	estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]
d1a29a__d1uhib___1	Metazoa	Metazoa	Chordata	Cnidaria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]; calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]; calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]	calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	bioluminescence [GO:0008218]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]		calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]	calcium ion binding [GO:0005509]
d1a2ba__d2jlra1__1	Metazoa		Chordata		apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1a2c.1_d3rxoa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1a2ia__d1czja___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	anaerobic respiration [GO:0009061]	anaerobic respiration [GO:0009061]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1a2ka__d1gybd___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	cytoplasm [GO:0005737]; nuclear envelope [GO:0005635]; nuclear pore central transport channel [GO:0044613]; Ran GTPase binding [GO:0008536]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; nuclear envelope [GO:0005635]; nuclear pore central transport channel [GO:0044613]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	Ran GTPase binding [GO:0008536]
d1a2ka__d3mg3b2__1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	phycobilisome [GO:0030089]; chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]; light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	phycobilisome [GO:0030089]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]
d1a2kc__d3w3zb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; melanosome [GO:0042470]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RISC complex [GO:0016442]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; nuclear export signal receptor activity [GO:0005049]; pre-miRNA binding [GO:0070883]; RISC complex binding [GO:1905172]; cell division [GO:0051301]; GTP metabolic process [GO:0046039]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of protein export from nucleus [GO:0046827]; pre-miRNA export from nucleus [GO:0035281]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	cell division [GO:0051301]; GTP metabolic process [GO:0046039]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of protein export from nucleus [GO:0046827]; pre-miRNA export from nucleus [GO:0035281]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; melanosome [GO:0042470]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RISC complex [GO:0016442]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; nuclear export signal receptor activity [GO:0005049]; pre-miRNA binding [GO:0070883]; RISC complex binding [GO:1905172]
d1a2lb__d1w4vf1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein disulfide oxidoreductase activity [GO:0015035]; protein-containing complex binding [GO:0044877]; cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein-containing complex binding [GO:0044877]; protein disulfide oxidoreductase activity [GO:0015035]
d1a2pa__d4hohb___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1a2ve2_d2cwta2__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]	peroxisome [GO:0005777]		aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d1a2wb__d1k58a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]
d1a2xa__d3bowb___1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]; troponin T binding [GO:0031014]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; proteolysis [GO:0006508]		proteolysis [GO:0006508]		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; troponin T binding [GO:0031014]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]
d1a2yb__d1waab___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1a30a__d5p1qa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	aspartic-type endopeptidase activity [GO:0004190]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1a3aa__d4gqxb___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity [GO:0022872]; protein-phosphocysteine-mannitol phosphotransferase system transporter activity [GO:0090565]; mannitol transport [GO:0015797]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	mannitol transport [GO:0015797]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity [GO:0022872]; protein-phosphocysteine-mannitol phosphotransferase system transporter activity [GO:0090565]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]
d1a3ad__d2a0ja___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity [GO:0022872]; protein-phosphocysteine-mannitol phosphotransferase system transporter activity [GO:0090565]; mannitol transport [GO:0015797]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	D-glucosamine PTS permease activity [GO:0103111]; kinase activity [GO:0016301]; protein kinase activator activity [GO:0030295]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; regulation of ion transmembrane transporter activity [GO:0032412]	mannitol transport [GO:0015797]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; regulation of ion transmembrane transporter activity [GO:0032412]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity [GO:0022872]; protein-phosphocysteine-mannitol phosphotransferase system transporter activity [GO:0090565]	D-glucosamine PTS permease activity [GO:0103111]; kinase activity [GO:0016301]; protein kinase activator activity [GO:0030295]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]
d1a3da__d2qvda___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1a3e.1_d4agka___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1a3fa__d3iq3b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]
d1a3ha__d1jyxd5__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1a3ha__d2xpkb2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d1a3lh2_d1vgeh1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1a3lh2_d1xr9a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1a3ll2_d3fo2l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1a3nd__d3vrgb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1a3oc__d2qssb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1a3oc__d2uumr___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1a3qa1_d2c9qa___1	Metazoa		Chordata	Proteobacteria	Bcl3/NF-kappaB2 complex [GO:0033257]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; aging [GO:0007568]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; rhythmic process [GO:0048511]; spleen development [GO:0048536]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	aging [GO:0007568]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; rhythmic process [GO:0048511]; spleen development [GO:0048536]	copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	Bcl3/NF-kappaB2 complex [GO:0033257]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	periplasmic space [GO:0042597]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]	copper ion binding [GO:0005507]
d1a3rh1_d1qfpa___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	carbohydrate binding [GO:0030246]
d1a3rl1_d1deee2__1				Firmicutes	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	pathogenesis [GO:0009405]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	IgG binding [GO:0019864]
d1a3wa3_d1aqfc3__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; glycolytic process [GO:0006096]; pyruvate metabolic process [GO:0006090]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	glycolytic process [GO:0006096]; pyruvate metabolic process [GO:0006090]	positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1a3wb3_d3hqpd3__1	Fungi		Ascomycota		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; glycolytic process [GO:0006096]; pyruvate metabolic process [GO:0006090]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	glycolytic process [GO:0006096]; pyruvate metabolic process [GO:0006090]		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1a3yb__d5hz8a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	small molecule binding [GO:0036094]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1a42a__d2it4b___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]
d1a43a__d2lf4a2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1a45a1_d1blbc1__1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			structural constituent of eye lens [GO:0005212]	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]
d1a45a2_d3hzbb___1	Metazoa		Chordata	Bacteroidetes	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1a47a1_d1cyga1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1a47a1_d1le9b1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	carbohydrate metabolic process [GO:0005975]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1a47a3_d5e6za3__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	extracellular region [GO:0005576]	cytosol [GO:0005829]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1a47a4_d1ur4a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]	metabolic process [GO:0008152]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]
d1a49f1_d1pkyd1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]; response to heat [GO:0009408]	positive regulation of sprouting angiogenesis [GO:1903672]	glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1a49h3_d1f3xb3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	positive regulation of sprouting angiogenesis [GO:1903672]	positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1a4ab__d5ldua3__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]			periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]
d1a4ba__d1e65d___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1a4ba__d4cspf1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1a4bb__d3fu8b2__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1a4ca__d4n2ha1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; chromatin-mediated maintenance of transcription [GO:0048096]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]		cellular response to leukemia inhibitory factor [GO:1990830]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin organization [GO:0006325]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]	periplasmic space [GO:0042597]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]
d1a4cc__d3d12e___1			Proteobacteria	Negarnaviricota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	periplasmic space [GO:0042597]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d1a4cd__d1gw0a3__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1a4fb__d3pi3b___1	Metazoa	Metazoa	Chordata	Mollusca	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1a4ga__d2bata___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1a4ga__d4ks5a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1a4gb__d3ti5b___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1a4ha__d2xhra___1	Fungi	Metazoa	Ascomycota	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1a4ib2_d2hk8c1__1	Metazoa		Chordata	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity [GO:0004486]; 10-formyltetrahydrofolate biosynthetic process [GO:0009257]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; folic acid metabolic process [GO:0046655]; heart development [GO:0007507]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; one-carbon metabolic process [GO:0006730]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; serine family amino acid biosynthetic process [GO:0009070]; serine family amino acid metabolic process [GO:0009069]; somite development [GO:0061053]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	10-formyltetrahydrofolate biosynthetic process [GO:0009257]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; folic acid metabolic process [GO:0046655]; heart development [GO:0007507]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; one-carbon metabolic process [GO:0006730]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; serine family amino acid biosynthetic process [GO:0009070]; serine family amino acid metabolic process [GO:0009069]; somite development [GO:0061053]; tetrahydrofolate interconversion [GO:0035999]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity [GO:0004486]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1a4ja2_d1uweu1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1a4jb1_d3vh8e___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1a4jb2_d4whtt2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	viral envelope [GO:0019031]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	viral envelope [GO:0019031]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1a4jh2_d3s37l1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cell junction [GO:0030054]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; sorting endosome [GO:0097443]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; growth factor binding [GO:0019838]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; angiogenesis [GO:0001525]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic hemopoiesis [GO:0035162]; endothelial cell differentiation [GO:0045446]; endothelium development [GO:0003158]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of gene expression [GO:0010629]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vasculogenesis [GO:2001214]; protein autophosphorylation [GO:0046777]; protein kinase B signaling [GO:0043491]; regulation of cell shape [GO:0008360]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	angiogenesis [GO:0001525]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic hemopoiesis [GO:0035162]; endothelial cell differentiation [GO:0045446]; endothelium development [GO:0003158]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of gene expression [GO:0010629]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vasculogenesis [GO:2001214]; protein autophosphorylation [GO:0046777]; protein kinase B signaling [GO:0043491]; regulation of cell shape [GO:0008360]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; sorting endosome [GO:0097443]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; growth factor binding [GO:0019838]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d1a4jl1_d1mhea1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1a4jl1_d3qxuc___1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1a4kh2_d2qr0a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1a4kl1_d2fjfk1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1a4qa__d1ms5b2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-sialidase activity [GO:0004308]
d1a4sa__d3injb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 4-trimethylammoniobutyraldehyde dehydrogenase activity [GO:0047105]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; carnitine biosynthetic process [GO:0045329]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	carnitine biosynthetic process [GO:0045329]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	4-trimethylammoniobutyraldehyde dehydrogenase activity [GO:0047105]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d1a4sa__d4ou2b___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; 4-trimethylammoniobutyraldehyde dehydrogenase activity [GO:0047105]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; carnitine biosynthetic process [GO:0045329]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	carnitine biosynthetic process [GO:0045329]		cytosol [GO:0005829]		4-trimethylammoniobutyraldehyde dehydrogenase activity [GO:0047105]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1a4ua__d5gwtc___1	Metazoa		Arthropoda	Firmicutes	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]; alcohol metabolic process [GO:0006066]	oxidoreductase activity [GO:0016491]	alcohol metabolic process [GO:0006066]				alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]	oxidoreductase activity [GO:0016491]
d1a4va__d1l41a___1	Metazoa		Chordata		extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]	host cell cytoplasm [GO:0030430]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]	lysozyme activity [GO:0003796]
d1a4va__d4j7va___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1a4w.1_d2a5aa___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1a4yb__d2k11a___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular exosome [GO:0070062]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	RNA phosphodiester bond hydrolysis [GO:0090501]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]
d1a4yd__d1dfji___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	extracellular region [GO:0005576]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1a4za__d4i2rd___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; ethanol catabolic process [GO:0006068]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	ethanol catabolic process [GO:0006068]		mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1a4zb__d5iuwb___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; ethanol catabolic process [GO:0006068]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; fermentation [GO:0006113]	ethanol catabolic process [GO:0006068]	fermentation [GO:0006113]	mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]
d1a4zc__d2d4ea___1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; ethanol catabolic process [GO:0006068]	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity [GO:0018480]; nucleotide binding [GO:0000166]; 4-hydroxyphenylacetate catabolic process [GO:1901023]	ethanol catabolic process [GO:0006068]	4-hydroxyphenylacetate catabolic process [GO:1901023]	mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity [GO:0018480]; nucleotide binding [GO:0000166]
d1a4zd__d4h80c___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; ethanol catabolic process [GO:0006068]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	ethanol catabolic process [GO:0006068]	aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	mitochondrial matrix [GO:0005759]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]
d1a4zd__d4zz7h___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; ethanol catabolic process [GO:0006068]	methylmalonate-semialdehyde dehydrogenase (acylating) activity [GO:0004491]; nucleotide binding [GO:0000166]	ethanol catabolic process [GO:0006068]		mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	methylmalonate-semialdehyde dehydrogenase (acylating) activity [GO:0004491]; nucleotide binding [GO:0000166]
d1a53a__d3b5va___1			Crenarchaeota		indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]		tryptophan biosynthetic process [GO:0000162]				indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]	
d1a55a__d3kjta___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	phosphate ion binding [GO:0042301]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1a56a__d5kafv___1			Proteobacteria	Cyanobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	integral component of membrane [GO:0016021]; photosystem II [GO:0009523]; thylakoid membrane [GO:0042651]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; photosystem II [GO:0009523]; thylakoid membrane [GO:0042651]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	
d1a58a__d1cwia___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	protein folding [GO:0006457]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1a5cb__d5dbuk___1			Apicomplexa	Firmicutes	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	glycolytic process [GO:0006096]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]		cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	deoxyribose-phosphate aldolase activity [GO:0004139]
d1a5da1_d1blbb1__1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			structural constituent of eye lens [GO:0005212]	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]
d1a5da2_d1npsa___1	Metazoa		Chordata	Proteobacteria	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	metal ion binding [GO:0046872]; sporulation resulting in formation of a cellular spore [GO:0030435]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	sporulation resulting in formation of a cellular spore [GO:0030435]			structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1a5db2_d4fd9b___1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	protein-containing complex [GO:0032991]; carbohydrate binding [GO:0030246]; protein kinase A binding [GO:0051018]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		protein-containing complex [GO:0032991]	structural constituent of eye lens [GO:0005212]	carbohydrate binding [GO:0030246]; protein kinase A binding [GO:0051018]; structural constituent of eye lens [GO:0005212]
d1a5fh2_d5jopd2__1												
d1a5fl1_d3ivkb2__1												
d1a5g.1_d1az8a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1a5qa__d1y92b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]		RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1a5ua3_d1f3wb3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	positive regulation of sprouting angiogenesis [GO:1903672]	positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1a5ue1_d3hqpg2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	positive regulation of sprouting angiogenesis [GO:1903672]		cytoplasm [GO:0005737]; nucleus [GO:0005634]		ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1a63a2_d1jb7b___1			Proteobacteria	Ciliophora	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	telomere capping [GO:0016233]	cytosol [GO:0005829]; membrane [GO:0016020]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1a66a__d5aomb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; FK506 binding [GO:0005528]; mitogen-activated protein kinase p38 binding [GO:0048273]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription coactivator binding [GO:0001225]; RNA polymerase II transcription factor binding [GO:0001085]; transcription factor binding [GO:0008134]; aortic valve morphogenesis [GO:0003180]; calcineurin-NFAT signaling cascade [GO:0033173]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; intracellular signal transduction [GO:0035556]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pulmonary valve morphogenesis [GO:0003184]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	aortic valve morphogenesis [GO:0003180]; calcineurin-NFAT signaling cascade [GO:0033173]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; intracellular signal transduction [GO:0035556]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pulmonary valve morphogenesis [GO:0003184]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; FK506 binding [GO:0005528]; mitogen-activated protein kinase p38 binding [GO:0048273]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription coactivator binding [GO:0001225]; RNA polymerase II transcription factor binding [GO:0001085]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1a67a__d3q2pa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular space [GO:0005615]; cysteine-type endopeptidase inhibitor activity [GO:0004869]				extracellular space [GO:0005615]		cysteine-type endopeptidase inhibitor activity [GO:0004869]	
d1a68a__d5bxbh1__1	Metazoa	Metazoa	Mollusca	Chordata	voltage-gated potassium channel complex [GO:0008076]; voltage-gated potassium channel activity [GO:0005249]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; identical protein binding [GO:0042802]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; protein homooligomerization [GO:0051260]	protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein homooligomerization [GO:0051260]	voltage-gated potassium channel complex [GO:0008076]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	voltage-gated potassium channel activity [GO:0005249]	identical protein binding [GO:0042802]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]
d1a6aa2_d1osza2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1a6ca1_d4wm8c___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1a6ca3_d1a6ca2__1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1a6ca3_d1oopc___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1a6db2_d1q3sd2__1			Euryarchaeota	Euryarchaeota	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	protein folding [GO:0006457]	protein folding [GO:0006457]			ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1a6ga__d2uumw___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1a6ja__d3bjva___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; enzyme inhibitor activity [GO:0004857]; kinase activity [GO:0016301]; protein kinase activator activity [GO:0030295]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; regulation of ion transmembrane transporter activity [GO:0032412]; response to organonitrogen compound [GO:0010243]	kinase activity [GO:0016301]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; regulation of ion transmembrane transporter activity [GO:0032412]; response to organonitrogen compound [GO:0010243]		cytosol [GO:0005829]		enzyme inhibitor activity [GO:0004857]; kinase activity [GO:0016301]; protein kinase activator activity [GO:0030295]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]	kinase activity [GO:0016301]
d1a6ta2_d2bvoa1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1a6tb1_d1t4ka2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1a6tb1_d3hfml1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1a6tb2_d4np4m1__1				Firmicutes		host cell plasma membrane [GO:0020002]; cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		host cell plasma membrane [GO:0020002]		cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]
d1a6tb2_d4yblc2__1						viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		viral envelope [GO:0019031]; virion membrane [GO:0055036]		
d1a6tc1_d3hi1l1__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1a6tc2_d2pcpd1__1												
d1a6td2_d1neza1__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1a6td2_d2vq1e1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1a6uh__d1n5yl2__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1a6vl__d1bihb3__1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	extracellular space [GO:0005615]; innate immune response [GO:0045087]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	innate immune response [GO:0045087]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	extracellular space [GO:0005615]		
d1a6vm__d5w59b1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; receptor-receptor interaction [GO:0090722]; SH2 domain binding [GO:0042169]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; auditory receptor cell development [GO:0060117]; branching involved in salivary gland morphogenesis [GO:0060445]; cell maturation [GO:0048469]; cell migration [GO:0016477]; chondrocyte differentiation [GO:0002062]; chordate embryonic development [GO:0043009]; embryonic limb morphogenesis [GO:0030326]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lung-associated mesenchyme development [GO:0060484]; MAPK cascade [GO:0000165]; mesenchymal cell differentiation [GO:0048762]; midbrain development [GO:0030901]; middle ear morphogenesis [GO:0042474]; negative regulation of fibroblast growth factor production [GO:0090272]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron migration [GO:0001764]; organ induction [GO:0001759]; outer ear morphogenesis [GO:0042473]; paraxial mesoderm development [GO:0048339]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle DNA replication [GO:1903465]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of parathyroid hormone secretion [GO:2000830]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cell differentiation [GO:0045595]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; regulation of lateral mesodermal cell fate specification [GO:0048378]; regulation of phosphate transport [GO:0010966]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular zone neuroblast division [GO:0021847]; vitamin D3 metabolic process [GO:0070640]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	angiogenesis [GO:0001525]; auditory receptor cell development [GO:0060117]; branching involved in salivary gland morphogenesis [GO:0060445]; cell maturation [GO:0048469]; cell migration [GO:0016477]; chondrocyte differentiation [GO:0002062]; chordate embryonic development [GO:0043009]; embryonic limb morphogenesis [GO:0030326]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lung-associated mesenchyme development [GO:0060484]; MAPK cascade [GO:0000165]; mesenchymal cell differentiation [GO:0048762]; midbrain development [GO:0030901]; middle ear morphogenesis [GO:0042474]; negative regulation of fibroblast growth factor production [GO:0090272]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron migration [GO:0001764]; organ induction [GO:0001759]; outer ear morphogenesis [GO:0042473]; paraxial mesoderm development [GO:0048339]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle DNA replication [GO:1903465]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of parathyroid hormone secretion [GO:2000830]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cell differentiation [GO:0045595]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; regulation of lateral mesodermal cell fate specification [GO:0048378]; regulation of phosphate transport [GO:0010966]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular zone neuroblast division [GO:0021847]; vitamin D3 metabolic process [GO:0070640]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; receptor-receptor interaction [GO:0090722]; SH2 domain binding [GO:0042169]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1a6vn__d1jtoa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1a6vn__d1zanl2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	adaptive immune response [GO:0002250]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]		
d1a6wh__d1wc7l2__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1a6wl__d1hnga1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; protein-containing complex [GO:0032991]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of tumor necrosis factor production [GO:0032760]; T cell activation [GO:0042110]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of tumor necrosis factor production [GO:0032760]; T cell activation [GO:0042110]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; protein-containing complex [GO:0032991]		protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]
d1a6zc1_d4xnql1__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d1a70a__d4us8a1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]			chloroplast [GO:0009507]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1a71a2_d4ijvb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytosol [GO:0005829]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d1a75b__d1j1dd___1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]		cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]		cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]	calcium ion binding [GO:0005509]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]
d1a77a1_d1taua1__1			Euryarchaeota	Deinococcus-Thermus	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; flap endonuclease activity [GO:0048256]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]			5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; flap endonuclease activity [GO:0048256]; magnesium ion binding [GO:0000287]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]
d1a78a__d1jyid___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]			extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1a79c1_d1r0vd1__1			Euryarchaeota	Euryarchaeota	tRNA-intron endonuclease complex [GO:0000214]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; tRNA-type intron splice site recognition and cleavage [GO:0000379]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	tRNA-type intron splice site recognition and cleavage [GO:0000379]	tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	tRNA-intron endonuclease complex [GO:0000214]		lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]
d1a79c2_d1r0vb3__1			Euryarchaeota	Euryarchaeota	tRNA-intron endonuclease complex [GO:0000214]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; tRNA-type intron splice site recognition and cleavage [GO:0000379]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	tRNA-type intron splice site recognition and cleavage [GO:0000379]	tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	tRNA-intron endonuclease complex [GO:0000214]		lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]
d1a7ha__d3so0c___1	Metazoa		Chordata	Firmicutes	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1a7kb2_d1yl7b2__1				Actinobacteria	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycosome [GO:0020015]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]
d1a7lb__d1hsla___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	outer membrane-bounded periplasmic space [GO:0030288]; amino acid binding [GO:0016597]; amino acid transport [GO:0006865]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	amino acid transport [GO:0006865]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	amino acid binding [GO:0016597]
d1a7lb__d4kr5b1__1			Proteobacteria	Firmicutes	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	nitrogen compound transport [GO:0071705]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	ligand-gated ion channel activity [GO:0015276]
d1a7oh__d3rnkb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1a7ph__d1ieba1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1a7pl__d1knof2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1a7ql__d4amkl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1a7rh__d1j88e2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	Fc-epsilon receptor signaling pathway [GO:0038095]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	IgE binding [GO:0019863]
d1a7rl__d2aj3e1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1a7tb__d3spue___1			Bacteroidetes	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d1a7xa__d5hw8b___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; fungal biofilm matrix [GO:0062040]; drug binding [GO:0008144]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; cellular response to drug [GO:0035690]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cellular response to drug [GO:0035690]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; fungal biofilm matrix [GO:0062040]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	drug binding [GO:0008144]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1a81e2_d1a09b___1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]
d1a86a__d3t74a___1	Metazoa		Chordata	Firmicutes	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]		collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1a88b__d1k5pa___1			Actinobacteria	Proteobacteria	chloride peroxidase activity [GO:0016691]	periplasmic space [GO:0042597]; haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]		response to toxic substance [GO:0009636]		periplasmic space [GO:0042597]	chloride peroxidase activity [GO:0016691]	haloalkane dehalogenase activity [GO:0018786]
d1a8da1_d5jmcg1__1			Firmicutes	Firmicutes	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1a8da2_d5g00a___1		Viridiplantae	Firmicutes	Streptophyta	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	endopeptidase inhibitor activity [GO:0004866]; peptidase activity [GO:0008233]	negative regulation of neurotransmitter secretion [GO:0046929]		clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	endopeptidase inhibitor activity [GO:0004866]; peptidase activity [GO:0008233]
d1a8ea__d1amfa___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	outer membrane-bounded periplasmic space [GO:0030288]; ATPase-coupled molybdate transmembrane transporter activity [GO:0015412]; molybdate ion binding [GO:0030973]; molybdenum ion binding [GO:0030151]; tungstate binding [GO:1901359]; molybdate ion transport [GO:0015689]; response to chromate [GO:0046687]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	molybdate ion transport [GO:0015689]; response to chromate [GO:0046687]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	outer membrane-bounded periplasmic space [GO:0030288]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	ATPase-coupled molybdate transmembrane transporter activity [GO:0015412]; molybdate ion binding [GO:0030973]; molybdenum ion binding [GO:0030151]; tungstate binding [GO:1901359]
d1a8gb__d5dq4a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1a8ha2_d2quja2__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; kinase inhibitor activity [GO:0019210]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tryptophan-tRNA ligase activity [GO:0004830]; angiogenesis [GO:0001525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; regulation of angiogenesis [GO:0045765]; regulation of protein ADP-ribosylation [GO:0010835]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]	methionyl-tRNA aminoacylation [GO:0006431]	angiogenesis [GO:0001525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; regulation of angiogenesis [GO:0045765]; regulation of protein ADP-ribosylation [GO:0010835]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; kinase inhibitor activity [GO:0019210]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tryptophan-tRNA ligase activity [GO:0004830]
d1a8jh1_d3cfea1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1a8jh2_d1uwel1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]	
d1a8jh2_d4wi3a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1a8jl1_d3kymo1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]	
d1a8jl1_d4ocmc___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	proteasome complex [GO:0000502]; proteasome regulatory particle, lid subcomplex [GO:0008541]; proteasome storage granule [GO:0034515]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; ubiquitin-dependent protein catabolic process [GO:0006511]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; ubiquitin-dependent protein catabolic process [GO:0006511]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	proteasome complex [GO:0000502]; proteasome regulatory particle, lid subcomplex [GO:0008541]; proteasome storage granule [GO:0034515]	antigen binding [GO:0003823]	
d1a8kb__d3s54b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]
d1a8kb__d5p01a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1a8kd__d3em3b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1a8la1_d4j2fa1__1		Viridiplantae	Euryarchaeota	Streptophyta	cell [GO:0005623]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; lactoylglutathione lyase activity [GO:0004462]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione transferase activity [GO:0004364]; lactoylglutathione lyase activity [GO:0004462]
d1a8la2_d3ik9c1__1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1a8pa1_d1i18a___1			Proteobacteria	Proteobacteria	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; riboflavin synthase activity [GO:0004746]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]		cytosol [GO:0005829]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	riboflavin synthase activity [GO:0004746]
d1a8pa2_d1cnfa2__1		Viridiplantae	Proteobacteria	Streptophyta	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; FAD binding [GO:0071949]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; nitrate reductase (NADH) activity [GO:0009703]; nitrate assimilation [GO:0042128]; nitric oxide biosynthetic process [GO:0006809]		nitrate assimilation [GO:0042128]; nitric oxide biosynthetic process [GO:0006809]		cytosol [GO:0005829]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	FAD binding [GO:0071949]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; nitrate reductase (NADH) activity [GO:0009703]
d1a8qa__d3x3hh___1		Viridiplantae	Actinobacteria	Streptophyta	peroxidase activity [GO:0004601]; antibiotic biosynthetic process [GO:0017000]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	antibiotic biosynthetic process [GO:0017000]				peroxidase activity [GO:0004601]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]
d1a8ra__d1a9ce___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1a8rb__d3plma1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1a8re__d3pkua1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1a8rf__d1vaxd1__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	
d1a8rh__d1gtpk___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1a8rh__d1ws3d1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1a8rl__d4du6c___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1a8rm__d1sqlg___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	dihydroneopterin aldolase activity [GO:0004150]
d1a8rn__d1fb1a___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]
d1a8ro__d4mb8d1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1a8ub__d1broa___1			Actinobacteria	Actinobacteria	chloride peroxidase activity [GO:0016691]	peroxidase activity [GO:0004601]; antibiotic biosynthetic process [GO:0017000]		antibiotic biosynthetic process [GO:0017000]			chloride peroxidase activity [GO:0016691]	peroxidase activity [GO:0004601]
d1a8ya2_d4xtsl___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of store-operated calcium channel activity [GO:1901341]; protein polymerization [GO:0051258]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of store-operated calcium entry [GO:2001256]; sarcomere organization [GO:0045214]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of store-operated calcium channel activity [GO:1901341]; protein polymerization [GO:0051258]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of store-operated calcium entry [GO:2001256]; sarcomere organization [GO:0045214]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]	cell [GO:0005623]; cytosol [GO:0005829]	calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]	thioredoxin peroxidase activity [GO:0008379]
d1a94d__d3u7sa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1a94e__d3nu6a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1a96b__d1p18a___1			Proteobacteria		cytosol [GO:0005829]; plasma membrane [GO:0005886]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; magnesium ion binding [GO:0000287]; xanthine phosphoribosyltransferase activity [GO:0000310]; GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	hypoxanthine phosphoribosyltransferase activity [GO:0004422]; magnesium ion binding [GO:0000287]; xanthine phosphoribosyltransferase activity [GO:0000310]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1a99d__d1bkaa1__1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; putrescine binding [GO:0019810]; putrescine transport [GO:0015847]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	putrescine transport [GO:0015847]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	putrescine binding [GO:0019810]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d1a9ba1_d1zt7c1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1a9ba1_d2q3ab___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1a9ba2_d3c5zc2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d1a9bb2_d4dk6b1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	mitochondrion [GO:0005739]; alpha-catenin binding [GO:0045294]; nucleic acid binding [GO:0003676]; mitochondrial RNA modification [GO:1900864]; RNA nucleotide deletion [GO:0070706]; RNA nucleotide insertion [GO:0070705]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	mitochondrial RNA modification [GO:1900864]; RNA nucleotide deletion [GO:0070706]; RNA nucleotide insertion [GO:0070705]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	alpha-catenin binding [GO:0045294]; nucleic acid binding [GO:0003676]
d1a9bb2_d4xbpl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1a9bd1_d1qkzl1__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	pathogenesis [GO:0009405]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	IgG binding [GO:0019864]
d1a9be2_d5gs1o___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1a9ca__d1n3rd___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1a9cc__d1r56f2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1a9cd__d4puva2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1a9ce__d5ll1g2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1a9cf__d2zkaa2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1a9ci__d1a8rc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1a9ck__d1gtpf___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1a9ck__d1j2gd2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]; allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]
d1a9cl__d1ws2b1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1a9cn__d3p9oa1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1a9da2_d2va4a2__1												
d1a9ea1_d1eo8h1__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]
d1a9eb2_d4bz1l1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	protein dimerization activity [GO:0046983]
d1a9va__d2wq8a3__1	Metazoa	Fungi	Arthropoda	Ascomycota	extracellular region [GO:0005576]	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]			extracellular region [GO:0005576]	extracellular region [GO:0005576]		galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]
d1a9wc__d1moba___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1a9wf__d3uhwa___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1a9xa2_d1ik4d___1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	methylglyoxal synthase activity [GO:0008929]
d1a9xa3_d1jdbh4__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1a9xc3_d5lyjf1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1a9xe2_d1s8aa___1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	methylglyoxal synthase activity [GO:0008929]
d1a9xe3_d2zdgc1__1			Proteobacteria	Deinococcus-Thermus	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1a9xe4_d2vpqa1__1			Proteobacteria	Firmicutes	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1a9xe4_d2w70b1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1aa1b2_d5hanj1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1aa1h2_d5haoa1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1aa1l2_d1rscc2__1	Viridiplantae		Streptophyta	Cyanobacteria	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1aa1l2_d4lf2b1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1aa4a__d2vnxx___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	chloroplast [GO:0009507]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1aa8a4_d2ignc2__1		Fungi		Basidiomycota		flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]						flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]
d1aa8b4_d2iidc2__1		Metazoa		Chordata		extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]		apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]		extracellular region [GO:0005576]		L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]
d1aaca__d1shxb___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	adherens junction [GO:0005912]; anchored component of external side of plasma membrane [GO:0031362]; basement membrane [GO:0005604]; caveola [GO:0005901]; cell periphery [GO:0071944]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]; chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; neurotrophin TRKB receptor binding [GO:0005169]; axon guidance [GO:0007411]; brain development [GO:0007420]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to forskolin [GO:1904322]; collateral sprouting [GO:0048668]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of synapse assembly [GO:0051965]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell morphogenesis [GO:0022604]; regulation of cell-cell adhesion [GO:0022407]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of microtubule cytoskeleton organization [GO:0070507]; retinal ganglion cell axon guidance [GO:0031290]; synaptic membrane adhesion [GO:0099560]		axon guidance [GO:0007411]; brain development [GO:0007420]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to forskolin [GO:1904322]; collateral sprouting [GO:0048668]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of synapse assembly [GO:0051965]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell morphogenesis [GO:0022604]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of microtubule cytoskeleton organization [GO:0070507]; retinal ganglion cell axon guidance [GO:0031290]; synaptic membrane adhesion [GO:0099560]	periplasmic space [GO:0042597]	adherens junction [GO:0005912]; anchored component of external side of plasma membrane [GO:0031362]; basement membrane [GO:0005604]; caveola [GO:0005901]; cell periphery [GO:0071944]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; neurotrophin TRKB receptor binding [GO:0005169]
d1aaca__d4qlwc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1aana__d1asqb1__1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]			periplasmic space [GO:0042597]	extracellular region [GO:0005576]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]
d1aaqb__d3vsxa___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d1aarb__d2iy1d___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d1aazb__d1syrd___1				Apicomplexa	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]; cytosol [GO:0005829]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d1aazb__d3vi5a1__1		Metazoa		Chordata	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1ab0a__d2g78a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1ab2a__d1is0a___1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]		actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]		actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]
d1ab3a__d3r66a___1		Metazoa	Deinococcus-Thermus	Chordata	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	translation [GO:0006412]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	ribosome [GO:0005840]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1ab5a__d3lten___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	DNA binding [GO:0003677]
d1ab5b__d1p6ua___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	
d1abaa__d4pokb1__1		Metazoa		Chordata	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d1abea__d1drja___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; ATPase-coupled monosaccharide transmembrane transporter activity [GO:0015407]; monosaccharide binding [GO:0048029]; L-arabinose transmembrane transport [GO:0042882]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; monosaccharide binding [GO:0048029]; D-ribose transmembrane transport [GO:0015752]; positive chemotaxis [GO:0050918]	L-arabinose transmembrane transport [GO:0042882]	D-ribose transmembrane transport [GO:0015752]; positive chemotaxis [GO:0050918]	outer membrane-bounded periplasmic space [GO:0030288]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	ATPase-coupled monosaccharide transmembrane transporter activity [GO:0015407]; monosaccharide binding [GO:0048029]	monosaccharide binding [GO:0048029]
d1abmb3_d4br6b1__1		Fungi		Ascomycota		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]						metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1abmb4_d1uesd2__1				Bacteroidetes		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]						metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1abmb4_d3qvna2__1		Fungi		Ascomycota		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]						metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1abra__d4jtpa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	galactose binding [GO:0005534]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]; positive regulation of endocytosis [GO:0045807]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]; positive regulation of endocytosis [GO:0045807]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			galactose binding [GO:0005534]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1absa__d1ebca___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1abwa2_d1cmyd___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1abwb__d2vmlf___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1abwd__d2gnwb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d1abya1_d5aqde___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1ac1a__d2h73b___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1ac4a__d1gx2b___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]; vacuole [GO:0005773]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1ac4a__d5sxsa1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1ac5a__d1beza___1	Fungi		Ascomycota	Proteobacteria	fungal-type vacuole [GO:0000324]; integral component of membrane [GO:0016021]; trans-Golgi network [GO:0005802]; serine-type carboxypeptidase activity [GO:0004185]; apoptotic process [GO:0006915]; proteolysis involved in cellular protein catabolic process [GO:0051603]	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	apoptotic process [GO:0006915]; proteolysis involved in cellular protein catabolic process [GO:0051603]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	fungal-type vacuole [GO:0000324]; integral component of membrane [GO:0016021]; trans-Golgi network [GO:0005802]		serine-type carboxypeptidase activity [GO:0004185]	haloalkane dehalogenase activity [GO:0018786]
d1ac8a__d1mhl.1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]; chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1acoa1_d3vbac___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	(R)-2-methylmalate dehydratase activity [GO:0047508]; 3-isopropylmalate dehydratase activity [GO:0003861]; maleate hydratase activity [GO:0050075]; isoleucine biosynthetic process [GO:0009097]; leucine biosynthetic process [GO:0009098]	citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	isoleucine biosynthetic process [GO:0009097]; leucine biosynthetic process [GO:0009098]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]	(R)-2-methylmalate dehydratase activity [GO:0047508]; 3-isopropylmalate dehydratase activity [GO:0003861]; maleate hydratase activity [GO:0050075]
d1acyh1_d3rajl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d1acyh2_d2xzal1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1acyl2_d1oarn___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ad0a2_d4l4te2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ad0b1_d4evnh1__1												
d1ad0b2_d1mrcl2__1												
d1ad0c1_d1ngxh1__1												
d1ad0c2_d2adfl2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ad0d1_d5u6qb1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ad0d2_d4y4fd1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1ad3b__d4o6rc1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1ad8.1_d5b6oa___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1ad9a1_d2vq1a1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ad9h1_d5d1ze2__1				Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]		heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]
d1ad9l1_d2xxmb1__1						host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ad9l2_d2dtgc1__1												
d1adcb2_d5bsgg1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cell wall [GO:0005618]; nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]; L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]	cytosol [GO:0005829]	cell wall [GO:0005618]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1adfa2_d1cdoa2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]
d1adja2_d2alyb6__1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	histidyl-tRNA aminoacylation [GO:0006427]	phenylalanyl-tRNA aminoacylation [GO:0006432]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]
d1adjb2_d1evld2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	histidyl-tRNA aminoacylation [GO:0006427]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1adjd2_d1b8ab2__1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	histidyl-tRNA aminoacylation [GO:0006427]	aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d1adqa2_d2bsua4__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1adqa2_d3knba1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1adqh2_d32c2a1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1adqh2_d3cfkd2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1adql1_d3dx9a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1adql2_d3r06l1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1adra__d3kz3a___1					DNA binding [GO:0003677]	virion [GO:0019012]; core promoter binding [GO:0001047]; identical protein binding [GO:0042802]; latency-replication decision [GO:0098689]; maintenance of viral latency [GO:0019044]; negative regulation of transcription by competitive promoter binding [GO:0010944]; positive regulation of viral transcription [GO:0050434]		latency-replication decision [GO:0098689]; maintenance of viral latency [GO:0019044]; negative regulation of transcription by competitive promoter binding [GO:0010944]; positive regulation of viral transcription [GO:0050434]		virion [GO:0019012]	DNA binding [GO:0003677]	core promoter binding [GO:0001047]; identical protein binding [GO:0042802]
d1adwb__d1ibyb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	metal ion binding [GO:0046872]			periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	metal ion binding [GO:0046872]
d1adyd1_d1h4sa1__1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	histidyl-tRNA aminoacylation [GO:0006427]	prolyl-tRNA aminoacylation [GO:0006433]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]
d1ae4a__d1mi3c___1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; glucuronolactone reductase activity [GO:0047941]; L-glucuronate reductase activity [GO:0047939]; mevaldate reductase (NADPH) activity [GO:0019726]; oxidoreductase activity [GO:0016491]; aldehyde catabolic process [GO:0046185]; cellular detoxification of aldehyde [GO:0110095]; D-glucuronate catabolic process [GO:0042840]; L-ascorbic acid biosynthetic process [GO:0019853]	oxidoreductase activity [GO:0016491]; D-xylose catabolic process [GO:0042843]	aldehyde catabolic process [GO:0046185]; cellular detoxification of aldehyde [GO:0110095]; D-glucuronate catabolic process [GO:0042840]; L-ascorbic acid biosynthetic process [GO:0019853]	D-xylose catabolic process [GO:0042843]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; glucuronolactone reductase activity [GO:0047941]; L-glucuronate reductase activity [GO:0047939]; mevaldate reductase (NADPH) activity [GO:0019726]; oxidoreductase activity [GO:0016491]	oxidoreductase activity [GO:0016491]
d1ae6h2_d1bj1j2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]
d1ae6h2_d5k8aa1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ae6l2_d1e6jh2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ae7a__d4h0qa___1	Metazoa		Chordata		extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]		arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]		extracellular region [GO:0005576]		calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	
d1ae8.1_d2blqa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1aeba__d4fm5a2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1aeda__d5aoga___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; plant-type cell wall [GO:0009505]; plasmodesma [GO:0009506]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]; plant-type cell wall [GO:0009505]; plasmodesma [GO:0009506]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1aeea__d1ht8b1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1aeea__d2cepa___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1aefa__d1h5la___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]; vacuole [GO:0005773]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1aeia__d1dk5a1__1	Metazoa	Viridiplantae	Cnidaria	Streptophyta	calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]	calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]					calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]
d1aeib__d1aiia___1	Metazoa	Metazoa	Cnidaria	Chordata	calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; specific granule [GO:0042581]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; phospholipase A2 inhibitor activity [GO:0019834]; animal organ regeneration [GO:0031100]; defense response to bacterium [GO:0042742]; hippocampus development [GO:0021766]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; positive regulation of angiogenesis [GO:0045766]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell migration [GO:0010595]; response to glucocorticoid [GO:0051384]; response to growth factor [GO:0070848]		animal organ regeneration [GO:0031100]; defense response to bacterium [GO:0042742]; hippocampus development [GO:0021766]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; positive regulation of angiogenesis [GO:0045766]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of endothelial cell migration [GO:0010595]; response to glucocorticoid [GO:0051384]; response to growth factor [GO:0070848]		axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; specific granule [GO:0042581]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; phospholipase A2 inhibitor activity [GO:0019834]
d1aeic__d2ie6a___1	Metazoa	Metazoa	Cnidaria	Chordata	calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]		blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]		axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]
d1aeja__d2n18a___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1aena__d3q3ua1__1	Fungi	Fungi	Ascomycota	Basidiomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1aeoa__d1u2je___1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]
d1aeoa__d1yyga___1	Fungi	Fungi	Ascomycota	Basidiomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]
d1aeqa__d1gx2a___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]; vacuole [GO:0005773]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1aeua__d5v4ob2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1aeva__d5sxta2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1af2a2_d1ux0b___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; pyrimidine nucleoside binding [GO:0001884]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]	cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; nucleobase-containing small molecule interconversion [GO:0015949]	cytidine deamination [GO:0009972]	cytosol [GO:0005829]	cytosol [GO:0005829]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; pyrimidine nucleoside binding [GO:0001884]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]
d1af2a2_d2a8nb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; pyrimidine nucleoside binding [GO:0001884]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; nucleobase-containing small molecule interconversion [GO:0015949]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; nucleobase-containing small molecule interconversion [GO:0015949]	tRNA wobble adenosine to inosine editing [GO:0002100]	cytosol [GO:0005829]		cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; pyrimidine nucleoside binding [GO:0001884]; zinc ion binding [GO:0008270]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]
d1af8a__d2ehta___1			Actinobacteria	Aquificae	antibiotic biosynthetic process [GO:0017000]	cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; phosphopantetheine binding [GO:0031177]; lipid A biosynthetic process [GO:0009245]	antibiotic biosynthetic process [GO:0017000]	lipid A biosynthetic process [GO:0009245]		cytosol [GO:0005829]		acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; phosphopantetheine binding [GO:0031177]
d1af9a1_d5duwa___1		Metazoa	Firmicutes	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]	negative regulation of neurotransmitter secretion [GO:0046929]	cell adhesion [GO:0007155]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d1afb11_d4wrca2__1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]
d1afb31_d2c6ua___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; defense response [GO:0006952]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; signal transduction by protein phosphorylation [GO:0023014]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cell surface receptor signaling pathway [GO:0007166]; defense response [GO:0006952]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; signal transduction by protein phosphorylation [GO:0023014]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]
d1afcb__d1iltb___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; interleukin-1 type I receptor antagonist activity [GO:0045352]; interleukin-1 type II receptor antagonist activity [GO:0045353]; interleukin-1, type I receptor binding [GO:0005150]; interleukin-1, type II receptor binding [GO:0005151]; acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; interleukin-1-mediated signaling pathway [GO:0070498]; lipid metabolic process [GO:0006629]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; response to glucocorticoid [GO:0051384]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; interleukin-1-mediated signaling pathway [GO:0070498]; lipid metabolic process [GO:0006629]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; response to glucocorticoid [GO:0051384]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-1, type II receptor binding [GO:0005151]; interleukin-1, type I receptor binding [GO:0005150]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; interleukin-1 type II receptor antagonist activity [GO:0045353]; interleukin-1 type I receptor antagonist activity [GO:0045352]
d1afcd__d1z2va1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1afcf__d5bowa1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-1 receptor binding [GO:0005149]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-1 receptor binding [GO:0005149]
d1afcg__d1itba___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]
d1afch__d1md6a___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; antifungal humoral response [GO:0019732]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-6 production [GO:0032715]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	antifungal humoral response [GO:0019732]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-6 production [GO:0032715]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]
d1afd21_d5bzra___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d1afla__d1m07a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	carbohydrate binding [GO:0030246]; endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]
d1afra__d1xvcc___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	fatty acid biosynthetic process [GO:0006633]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	chloroplast [GO:0009507]		acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1afrc__d1fz8b___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	fatty acid biosynthetic process [GO:0006633]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	chloroplast [GO:0009507]		acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1afua__d4x08b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	azurophil granule lumen [GO:0035578]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endonuclease activity [GO:0004519]; lipopolysaccharide binding [GO:0001530]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; neutrophil degranulation [GO:0043312]; RNA catabolic process [GO:0006401]		antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; neutrophil degranulation [GO:0043312]; RNA catabolic process [GO:0006401]	extracellular region [GO:0005576]	azurophil granule lumen [GO:0035578]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lipopolysaccharide binding [GO:0001530]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1afvh1_d3bikb___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of T cell apoptotic process [GO:0070234]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of T cell apoptotic process [GO:0070234]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d1afvh2_d1u91a1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d1afvk1_d1mvfa___1				Proteobacteria	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	protein-containing complex [GO:0032991]; double-stranded DNA binding [GO:0003690]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; toxin-antitoxin pair type II binding [GO:0097351]; protein heterooligomerization [GO:0051291]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	protein heterooligomerization [GO:0051291]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	protein-containing complex [GO:0032991]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	double-stranded DNA binding [GO:0003690]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; toxin-antitoxin pair type II binding [GO:0097351]
d1afvk1_d5dt1l1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d1afvk2_d3eyoc1__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1afvl1_d1rzjh1__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1afvl1_d3v0vb1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d1afvl2_d1xgqa1__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1afwa2_d4o9cg2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acetyl-CoA C-acyltransferase activity [GO:0003988]; mRNA binding [GO:0003729]; fatty acid beta-oxidation [GO:0006635]; phenylacetate catabolic process [GO:0010124]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid beta-oxidation [GO:0006635]; phenylacetate catabolic process [GO:0010124]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	mitochondrial intermembrane space [GO:0005758]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cytoplasm [GO:0005737]	acetyl-CoA C-acyltransferase activity [GO:0003988]; mRNA binding [GO:0003729]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1afwb2_d1og9d4__1	Fungi		Ascomycota		mitochondrial intermembrane space [GO:0005758]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acetyl-CoA C-acyltransferase activity [GO:0003988]; mRNA binding [GO:0003729]; fatty acid beta-oxidation [GO:0006635]; phenylacetate catabolic process [GO:0010124]		fatty acid beta-oxidation [GO:0006635]; phenylacetate catabolic process [GO:0010124]		mitochondrial intermembrane space [GO:0005758]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		acetyl-CoA C-acyltransferase activity [GO:0003988]; mRNA binding [GO:0003729]	
d1ag1t__d2y70c___1					cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1ag4a__d3i9hb___1				Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; cell-cell adhesion [GO:0098609]	metal ion binding [GO:0046872]	cell-cell adhesion [GO:0098609]		cytoplasm [GO:0005737]; membrane [GO:0016020]			metal ion binding [GO:0046872]
d1ag6a__d5u7nd___1	Viridiplantae		Streptophyta	Deinococcus-Thermus	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]			chloroplast thylakoid membrane [GO:0009535]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1ag8d__d5eebh___1	Metazoa		Chordata	Crenarchaeota	mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; ethanol catabolic process [GO:0006068]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	ethanol catabolic process [GO:0006068]		mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1ag9a__d3nhsa___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1ag9b__d1flda___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]			cytoplasm [GO:0005737]; cytosol [GO:0005829]		electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1agba2_d1lnue2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d1agca1_d1tjgl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1agca2_d4p4ra1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d1agda2_d5ksub1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of membrane [GO:0016021]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; macrophage migration inhibitory factor receptor complex [GO:0035692]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; NOS2-CD74 complex [GO:0035693]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; vacuole [GO:0005773]; amyloid-beta binding [GO:0001540]; CD4 receptor binding [GO:0042609]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; macrophage migration inhibitory factor binding [GO:0035718]; MHC class II protein binding [GO:0042289]; MHC class II protein binding, via antigen binding groove [GO:0042658]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase binding [GO:0050998]; protein folding chaperone [GO:0044183]; activation of MAPK activity [GO:0000187]; antigen processing and presentation of endogenous antigen [GO:0019883]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell population proliferation [GO:0008283]; chaperone cofactor-dependent protein refolding [GO:0051085]; defense response [GO:0006952]; immunoglobulin mediated immune response [GO:0016064]; intracellular protein transport [GO:0006886]; leukocyte migration [GO:0050900]; macrophage migration inhibitory factor signaling pathway [GO:0035691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of peptide secretion [GO:0002792]; negative regulation of T cell differentiation [GO:0045581]; negative thymic T cell selection [GO:0045060]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of kinase activity [GO:0033674]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of macrophage migration inhibitory factor signaling pathway [GO:2000448]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of viral entry into host cell [GO:0046598]; positive thymic T cell selection [GO:0045059]; prostaglandin biosynthetic process [GO:0001516]; protein heterotetramerization [GO:0051290]; protein trimerization [GO:0070206]; protein-containing complex assembly [GO:0065003]; regulation of macrophage activation [GO:0043030]; signal transduction [GO:0007165]; T cell selection [GO:0045058]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of MAPK activity [GO:0000187]; antigen processing and presentation of endogenous antigen [GO:0019883]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell population proliferation [GO:0008283]; chaperone cofactor-dependent protein refolding [GO:0051085]; defense response [GO:0006952]; immunoglobulin mediated immune response [GO:0016064]; intracellular protein transport [GO:0006886]; leukocyte migration [GO:0050900]; macrophage migration inhibitory factor signaling pathway [GO:0035691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of peptide secretion [GO:0002792]; negative regulation of T cell differentiation [GO:0045581]; negative thymic T cell selection [GO:0045060]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of kinase activity [GO:0033674]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of macrophage migration inhibitory factor signaling pathway [GO:2000448]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of viral entry into host cell [GO:0046598]; positive thymic T cell selection [GO:0045059]; prostaglandin biosynthetic process [GO:0001516]; protein-containing complex assembly [GO:0065003]; protein heterotetramerization [GO:0051290]; protein trimerization [GO:0070206]; regulation of macrophage activation [GO:0043030]; signal transduction [GO:0007165]; T cell selection [GO:0045058]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of membrane [GO:0016021]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; macrophage migration inhibitory factor receptor complex [GO:0035692]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; NOS2-CD74 complex [GO:0035693]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; vacuole [GO:0005773]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	amyloid-beta binding [GO:0001540]; CD4 receptor binding [GO:0042609]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; macrophage migration inhibitory factor binding [GO:0035718]; MHC class II protein binding [GO:0042289]; MHC class II protein binding, via antigen binding groove [GO:0042658]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase binding [GO:0050998]; protein folding chaperone [GO:0044183]
d1agdb__d1mq8c2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]
d1agdb__d3hzva2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ageb__d4py7j1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1agfa2_d3o9wa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1agja__d1arba___1			Firmicutes	Proteobacteria	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]				extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	serine-type endopeptidase activity [GO:0004252]
d1agjb__d2z3ea___1			Firmicutes		serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1agma__d2a8za1__1	Fungi		Ascomycota	Proteobacteria	glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]			glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]	endo-1,4-beta-xylanase activity [GO:0031176]
d1agnc2_d3w6za1__1	Metazoa		Chordata	Crenarchaeota	cytosol [GO:0005829]; plasma membrane [GO:0005886]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; plasma membrane [GO:0005886]		alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]
d1agnd2_d1nxqa___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; plasma membrane [GO:0005886]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; plasma membrane [GO:0005886]		alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1agpa__d1u90a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cleavage furrow [GO:0032154]; Flemming body [GO:0090543]; plasma membrane [GO:0005886]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; cell cycle [GO:0007049]; cell division [GO:0051301]; exocytosis [GO:0006887]; membrane raft localization [GO:0051665]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell cycle [GO:0007049]; cell division [GO:0051301]; exocytosis [GO:0006887]; membrane raft localization [GO:0051665]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cleavage furrow [GO:0032154]; Flemming body [GO:0090543]; plasma membrane [GO:0005886]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1ah1a__d5ip4a1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	axoneme [GO:0005930]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; neuron projection [GO:0043005]; microtubule binding [GO:0008017]; protein kinase binding [GO:0019901]; axoneme assembly [GO:0035082]; central nervous system development [GO:0007417]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; photoreceptor cell development [GO:0042461]; retina development in camera-type eye [GO:0060041]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	axoneme assembly [GO:0035082]; central nervous system development [GO:0007417]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; photoreceptor cell development [GO:0042461]; retina development in camera-type eye [GO:0060041]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]	axoneme [GO:0005930]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; neuron projection [GO:0043005]		microtubule binding [GO:0008017]; protein kinase binding [GO:0019901]
d1ah2a__d1c3la___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1ahea__d1mapa___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]
d1ahga__d3aelb___1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d1ahka__d3p2da1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]	clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; endocytic vesicle [GO:0030139]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; angiotensin receptor binding [GO:0031701]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]		desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]	extracellular region [GO:0005576]	clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; endocytic vesicle [GO:0030139]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		angiotensin receptor binding [GO:0031701]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol binding [GO:0035091]
d1ahna__d4h2da___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity [GO:0016491]; cell death [GO:0008219]; cellular response to menadione [GO:0036245]; iron-sulfur cluster assembly [GO:0016226]; oxidation-reduction process [GO:0055114]		cell death [GO:0008219]; cellular response to menadione [GO:0036245]; iron-sulfur cluster assembly [GO:0016226]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity [GO:0016491]
d1ahqa__d1npha3__1		Metazoa		Chordata	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; actin polymerization or depolymerization [GO:0008154]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; barbed-end actin filament capping [GO:0051016]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]; vesicle-mediated transport [GO:0016192]	actin filament depolymerization [GO:0030042]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; actin polymerization or depolymerization [GO:0008154]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; barbed-end actin filament capping [GO:0051016]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]; vesicle-mediated transport [GO:0016192]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]	actin binding [GO:0003779]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1ahsb__d4kdnc1__1				Negarnaviricota	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]; host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]; fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d1ahsc__d4fp8c___1				Negarnaviricota	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]; host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]; fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]	host cell surface receptor binding [GO:0046789]
d1aht.1_d2bqwb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1ahua2_d1n5wc2__1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]		FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1ahub1_d5mxub2__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1ahva2_d2w3ra3__1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]		FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1ahwa2_d1ngya2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ahwb2_d4pj5f___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ahwc2_d2djsa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium tip [GO:0032433]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; protein-containing complex binding [GO:0044877]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; immunological synapse formation [GO:0001771]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle satellite cell activation [GO:0014719]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; immunological synapse formation [GO:0001771]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle satellite cell activation [GO:0014719]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium tip [GO:0032433]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; protein-containing complex binding [GO:0044877]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1ahwe2_d3bewe___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	protein homodimerization activity [GO:0042803]
d1ahyb__d4y0dd___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]
d1ahyb__d5ax8c___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T-tubule [GO:0030315]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; RNA binding [GO:0003723]; 2-oxoglutarate metabolic process [GO:0006103]; 4-hydroxyproline catabolic process [GO:0019470]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glyoxylate metabolic process [GO:0046487]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	2-oxoglutarate metabolic process [GO:0006103]; 4-hydroxyproline catabolic process [GO:0019470]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glyoxylate metabolic process [GO:0046487]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T-tubule [GO:0030315]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; RNA binding [GO:0003723]
d1ahza1_d4ml8a2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]	methanol metabolic process [GO:0015945]	cytokinin metabolic process [GO:0009690]	peroxisome [GO:0005777]		FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]
d1ahza2_d1rm6e2__1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]		FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]
d1ahzb1_d1w1ja1__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1ahzb1_d5fxeb2__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]		FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1ai1h2_d1rhhc1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ai7.1_d4qz6y___1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	periplasmic space [GO:0042597]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ai9a__d3ex8c2__1	Fungi		Ascomycota	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	riboflavin biosynthetic process [GO:0009231]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d1ai9b__d4km2a___1	Fungi		Ascomycota	Actinobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]
d1aiaa__d1gc3h___1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]; aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]
d1aica__d4ah3b___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]
d1aida__d1w6ia___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1aifa2_d3bn9d1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1aifh2_d1b88a___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1aipa2_d4iw3k3__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1aipb2_d4qfma3__1			Deinococcus-Thermus	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1aipc2_d4pc6d3__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1aira__d4c2la___1		Fungi	Proteobacteria	Ascomycota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	polygalacturonase activity [GO:0004650]
d1aisa1_d1ngme1__1		Fungi	Euryarchaeota	Ascomycota	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA-templated transcription, initiation [GO:0006352]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]		nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]
d1aisa1_d3cvsb2__1			Euryarchaeota	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1aisa2_d1mp9a1__1			Euryarchaeota	Crenarchaeota	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1aisa2_d3cvsa2__1			Euryarchaeota	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1aiza__d1l9rb2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1aizb__d3jtbd___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1aj4a__d1rtp1___1	Metazoa	Metazoa	Chordata	Chordata	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cochlea development [GO:0090102]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cochlea development [GO:0090102]	troponin complex [GO:0005861]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d1aj5a__d2jt0a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; proteolysis [GO:0006508]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	proteolysis [GO:0006508]	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]
d1aj7h2_d3bz4g2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1aj7l1_d4xbgb2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1aj7l2_d1ocwh___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1aj8b__d3l96b___1			Euryarchaeota		cytoplasm [GO:0005737]; transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]		transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]	
d1ajga__d3nfea___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ajn.1_d1oqza___1			Proteobacteria		periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]		antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]	
d1ajoa__d3azzc___1			Firmicutes	Thermotogae	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			licheninase activity [GO:0042972]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1ajsa__d4xaue1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; phosphatidylserine decarboxylase activity [GO:0004609]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular response to insulin stimulus [GO:0032869]; fatty acid homeostasis [GO:0055089]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; response to glucocorticoid [GO:0051384]	transaminase activity [GO:0008483]	2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular response to insulin stimulus [GO:0032869]; fatty acid homeostasis [GO:0055089]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; response to glucocorticoid [GO:0051384]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]		L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; phosphatidylserine decarboxylase activity [GO:0004609]; pyridoxal phosphate binding [GO:0030170]	transaminase activity [GO:0008483]
d1ajva__d1b5f.2__1		Viridiplantae		Streptophyta	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cell wall [GO:0005618]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; organelle membrane [GO:0031090]; protein storage vacuole [GO:0000326]; aspartic-type endopeptidase activity [GO:0004190]; lipid metabolic process [GO:0006629]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	lipid metabolic process [GO:0006629]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cell wall [GO:0005618]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; organelle membrane [GO:0031090]; protein storage vacuole [GO:0000326]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1ajwa__d1j0ia1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]		GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1ajwa__d5e80a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	response to stimulus [GO:0050896]; visual perception [GO:0007601]	cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]
d1ajxa__d3ekvb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ak4a__d1j2aa___1				Proteobacteria	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	outer membrane-bounded periplasmic space [GO:0030288]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	outer membrane-bounded periplasmic space [GO:0030288]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1ak7a__d1tvja___1	Metazoa	Metazoa	Chordata	Chordata	cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]; actin filament severing [GO:0051014]; positive regulation of actin filament depolymerization [GO:0030836]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]	actin filament depolymerization [GO:0030042]; actin filament severing [GO:0051014]; positive regulation of actin filament depolymerization [GO:0030836]	actin filament depolymerization [GO:0030042]	cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]	actin binding [GO:0003779]	actin binding [GO:0003779]
d1akaa__d2oatb___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]	ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]
d1akda__d4l4fa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	(+)-camphor catabolic process [GO:0019383]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1akia__d5vnqa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1akjb__d3hnvl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1akje__d2om5a4__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	anchored component of postsynaptic membrane [GO:0099025]; axon [GO:0030424]; cell surface [GO:0009986]; juxtaparanode region of axon [GO:0044224]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; node of Ranvier [GO:0033268]; plasma membrane [GO:0005886]; synapse [GO:0045202]; carbohydrate binding [GO:0030246]; cell-cell adhesion mediator activity [GO:0098632]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]; adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cerebral cortex GABAergic interneuron migration [GO:0021853]; clustering of voltage-gated potassium channels [GO:0045163]; dendrite self-avoidance [GO:0070593]; establishment of protein localization to juxtaparanode region of axon [GO:0071206]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; learning [GO:0007612]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; positive regulation of protein processing [GO:0010954]; presynaptic membrane organization [GO:0097090]; protein localization to juxtaparanode region of axon [GO:0071205]; receptor internalization [GO:0031623]; regulation of astrocyte differentiation [GO:0048710]; regulation of axon diameter [GO:0031133]; regulation of neuronal synaptic plasticity [GO:0048168]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adult walking behavior [GO:0007628]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cerebral cortex GABAergic interneuron migration [GO:0021853]; clustering of voltage-gated potassium channels [GO:0045163]; dendrite self-avoidance [GO:0070593]; establishment of protein localization to juxtaparanode region of axon [GO:0071206]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; learning [GO:0007612]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; positive regulation of protein processing [GO:0010954]; presynaptic membrane organization [GO:0097090]; protein localization to juxtaparanode region of axon [GO:0071205]; receptor internalization [GO:0031623]; regulation of astrocyte differentiation [GO:0048710]; regulation of axon diameter [GO:0031133]; regulation of neuronal synaptic plasticity [GO:0048168]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	anchored component of postsynaptic membrane [GO:0099025]; axon [GO:0030424]; cell surface [GO:0009986]; juxtaparanode region of axon [GO:0044224]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; node of Ranvier [GO:0033268]; plasma membrane [GO:0005886]; synapse [GO:0045202]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; cell-cell adhesion mediator activity [GO:0098632]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]
d1akoa__d3i41b___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; exodeoxyribonuclease III activity [GO:0008853]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]		cytosol [GO:0005829]	extracellular region [GO:0005576]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; exodeoxyribonuclease III activity [GO:0008853]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081]
d1akqa__d2qmzb___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1akta__d1kboc___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d1akva__d1t0ia___1		Fungi	Proteobacteria	Ascomycota	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; FMN binding [GO:0010181]; FMN reductase (NADH) activity [GO:0052874]; FMN reductase (NADPH) activity [GO:0052873]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; transcription factor binding [GO:0008134]; apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]		apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	FMN binding [GO:0010181]; FMN reductase (NADH) activity [GO:0052874]; FMN reductase (NADPH) activity [GO:0052873]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; transcription factor binding [GO:0008134]
d1akwa__d3o73b___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1akwa__d4heqb___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1alaa__d1axna___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; vesicle [GO:0031982]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]; calcium ion homeostasis [GO:0055074]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; specific granule [GO:0042581]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; phospholipase A2 inhibitor activity [GO:0019834]; animal organ regeneration [GO:0031100]; defense response to bacterium [GO:0042742]; hippocampus development [GO:0021766]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; positive regulation of angiogenesis [GO:0045766]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell migration [GO:0010595]; response to glucocorticoid [GO:0051384]; response to growth factor [GO:0070848]	calcium ion homeostasis [GO:0055074]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	animal organ regeneration [GO:0031100]; defense response to bacterium [GO:0042742]; hippocampus development [GO:0021766]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; positive regulation of angiogenesis [GO:0045766]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of endothelial cell migration [GO:0010595]; response to glucocorticoid [GO:0051384]; response to growth factor [GO:0070848]	calcium channel complex [GO:0034704]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; vesicle [GO:0031982]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; specific granule [GO:0042581]	calcium channel activity [GO:0005262]; calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; phospholipase A2 inhibitor activity [GO:0019834]
d1alca__d148le___1	Metazoa		Chordata		extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; lactose biosynthetic process [GO:0005989]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	lactose biosynthetic process [GO:0005989]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]	host cell cytoplasm [GO:0030430]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]	lysozyme activity [GO:0003796]
d1alda__d1wa3d___1	Metazoa		Chordata	Thermotogae	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; I band [GO:0031674]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]; sperm head [GO:0061827]; tertiary granule lumen [GO:1904724]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; fructose binding [GO:0070061]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; tubulin binding [GO:0015631]; actin filament organization [GO:0007015]; ATP biosynthetic process [GO:0006754]; binding of sperm to zona pellucida [GO:0007339]; canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; muscle cell cellular homeostasis [GO:0046716]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; protein homotetramerization [GO:0051289]; regulation of cell shape [GO:0008360]; striated muscle contraction [GO:0006941]	lyase activity [GO:0016829]	actin filament organization [GO:0007015]; ATP biosynthetic process [GO:0006754]; binding of sperm to zona pellucida [GO:0007339]; canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; muscle cell cellular homeostasis [GO:0046716]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; protein homotetramerization [GO:0051289]; regulation of cell shape [GO:0008360]; striated muscle contraction [GO:0006941]		actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; I band [GO:0031674]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]; sperm head [GO:0061827]; tertiary granule lumen [GO:1904724]		actin binding [GO:0003779]; cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; fructose binding [GO:0070061]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; tubulin binding [GO:0015631]	lyase activity [GO:0016829]
d1alia__d3bdha___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1alib__d3t01a___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]
d1alja__d3t02a___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]
d1alla__d5hlqa___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1am4a__d3byic___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	GTPase activator activity [GO:0005096]
d1amia1_d1b0ma1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; metal ion binding [GO:0046872]; tricarboxylic acid cycle [GO:0006099]	citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]	4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; metal ion binding [GO:0046872]
d1amka__d4ohqa___1		Viridiplantae		Streptophyta	glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; thylakoid [GO:0009579]; triose-phosphate isomerase activity [GO:0004807]; chloroplast organization [GO:0009658]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; multicellular organism reproduction [GO:0032504]; primary root development [GO:0080022]; reductive pentose-phosphate cycle [GO:0019253]; triglyceride mobilization [GO:0006642]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	chloroplast organization [GO:0009658]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; multicellular organism reproduction [GO:0032504]; primary root development [GO:0080022]; reductive pentose-phosphate cycle [GO:0019253]; triglyceride mobilization [GO:0006642]	glycosome [GO:0020015]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; thylakoid [GO:0009579]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1amma2_d2m3ua2__1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]			structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d1amoa2_d1ofva___1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1amob3_d1qfjc2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cytosol [GO:0005829]; enzyme activator activity [GO:0008047]; riboflavin reductase (NADH) activity [GO:0052875]; riboflavin reductase (NADPH) activity [GO:0042602]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	enzyme activator activity [GO:0008047]; riboflavin reductase (NADH) activity [GO:0052875]; riboflavin reductase (NADPH) activity [GO:0042602]
d1amwa__d1s14a___1	Fungi		Ascomycota	Proteobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	chromosome [GO:0005694]; cytosol [GO:0005829]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; chromosome organization [GO:0051276]; DNA topological change [GO:0006265]; plasmid partitioning [GO:0030541]; response to antibiotic [GO:0046677]; sister chromatid cohesion [GO:0007062]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	chromosome organization [GO:0051276]; DNA topological change [GO:0006265]; plasmid partitioning [GO:0030541]; response to antibiotic [GO:0046677]; sister chromatid cohesion [GO:0007062]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	chromosome [GO:0005694]; cytosol [GO:0005829]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d1amya2_d1jyzi5__1	Viridiplantae		Streptophyta		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	
d1an2a__d1r05a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; dendrite [GO:0030425]; MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; E-box binding [GO:0070888]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to starvation [GO:0009267]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; response to axon injury [GO:0048678]; response to insulin [GO:0032868]; retina development in camera-type eye [GO:0060041]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; dendrite [GO:0030425]; MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; E-box binding [GO:0070888]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to starvation [GO:0009267]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; response to axon injury [GO:0048678]; response to insulin [GO:0032868]; retina development in camera-type eye [GO:0060041]; transcription by RNA polymerase II [GO:0006366]	cellular response to peptide hormone stimulus [GO:0071375]; cellular response to starvation [GO:0009267]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; response to axon injury [GO:0048678]; response to insulin [GO:0032868]; retina development in camera-type eye [GO:0060041]; transcription by RNA polymerase II [GO:0006366]	cellular response to peptide hormone stimulus [GO:0071375]; cellular response to starvation [GO:0009267]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; response to axon injury [GO:0048678]; response to insulin [GO:0032868]; retina development in camera-type eye [GO:0060041]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; dendrite [GO:0030425]; MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]	cytoplasm [GO:0005737]; dendrite [GO:0030425]; MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; E-box binding [GO:0070888]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; E-box binding [GO:0070888]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]
d1an8a2_d1fnub2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1an9a2_d1pj5a3__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]		cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]		D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]
d1anda__d2xyaa1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1anea__d5dp5a1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1anfa__d1ixia___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	phosphate ion binding [GO:0042301]
d1anna__d1dm5f___1	Metazoa	Metazoa	Chordata	Cnidaria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; carbohydrate binding [GO:0030246]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; epithelial cell differentiation [GO:0030855]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription by RNA polymerase II [GO:0006357]	calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]	epithelial cell differentiation [GO:0030855]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription by RNA polymerase II [GO:0006357]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]		calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]
d1anna__d2hywb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; carbohydrate binding [GO:0030246]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; epithelial cell differentiation [GO:0030855]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription by RNA polymerase II [GO:0006357]	azurophil granule lumen [GO:0035578]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell cortex [GO:0005938]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; macropinosome [GO:0044354]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; myelin sheath adaxonal region [GO:0035749]; nucleus [GO:0005634]; PCSK9-AnxA2 complex [GO:1990667]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; sarcolemma [GO:0042383]; Schmidt-Lanterman incisure [GO:0043220]; vesicle [GO:0031982]; bone sialoprotein binding [GO:0044730]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; molecular function regulator [GO:0098772]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipase A2 inhibitor activity [GO:0019834]; protease binding [GO:0002020]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; virion binding [GO:0046790]; voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [GO:0099511]; angiogenesis [GO:0001525]; biomineral tissue development [GO:0031214]; body fluid secretion [GO:0007589]; catabolism by host of symbiont protein [GO:0052362]; collagen fibril organization [GO:0030199]; endocardial cell differentiation [GO:0060956]; fibrinolysis [GO:0042730]; growth plate cartilage development [GO:0003417]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane raft assembly [GO:0001765]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of development of symbiont involved in interaction with host [GO:0044147]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; neutrophil degranulation [GO:0043312]; osteoclast development [GO:0036035]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of low-density lipoprotein particle receptor binding [GO:1905597]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor recycling [GO:0001921]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of vacuole organization [GO:0044090]; positive regulation of vesicle fusion [GO:0031340]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; regulation of plasminogen activation [GO:0010755]; response to thyroid hormone [GO:0097066]; vesicle budding from membrane [GO:0006900]	epithelial cell differentiation [GO:0030855]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription by RNA polymerase II [GO:0006357]	angiogenesis [GO:0001525]; biomineral tissue development [GO:0031214]; body fluid secretion [GO:0007589]; catabolism by host of symbiont protein [GO:0052362]; collagen fibril organization [GO:0030199]; endocardial cell differentiation [GO:0060956]; fibrinolysis [GO:0042730]; growth plate cartilage development [GO:0003417]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane raft assembly [GO:0001765]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of development of symbiont involved in interaction with host [GO:0044147]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; neutrophil degranulation [GO:0043312]; osteoclast development [GO:0036035]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of low-density lipoprotein particle receptor binding [GO:1905597]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of receptor recycling [GO:0001921]; positive regulation of vacuole organization [GO:0044090]; positive regulation of vesicle fusion [GO:0031340]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; regulation of plasminogen activation [GO:0010755]; response to thyroid hormone [GO:0097066]; vesicle budding from membrane [GO:0006900]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	azurophil granule lumen [GO:0035578]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; macropinosome [GO:0044354]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; myelin sheath adaxonal region [GO:0035749]; nucleus [GO:0005634]; PCSK9-AnxA2 complex [GO:1990667]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; sarcolemma [GO:0042383]; Schmidt-Lanterman incisure [GO:0043220]; vesicle [GO:0031982]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]	bone sialoprotein binding [GO:0044730]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium channel activity [GO:0005262]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; molecular function regulator [GO:0098772]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipase A2 inhibitor activity [GO:0019834]; protease binding [GO:0002020]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; virion binding [GO:0046790]; voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [GO:0099511]
d1anwa__d2zocb___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phospholipase inhibitor activity [GO:0004859]; epithelial cell differentiation [GO:0030855]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phospholipase inhibitor activity [GO:0004859]
d1anxa__d1yiia___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	calcium channel complex [GO:0034704]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; vesicle [GO:0031982]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]; calcium ion homeostasis [GO:0055074]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	calcium ion homeostasis [GO:0055074]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]	calcium channel complex [GO:0034704]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; vesicle [GO:0031982]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]	calcium channel activity [GO:0005262]; calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]
d1anxc__d2zoca___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phospholipase inhibitor activity [GO:0004859]; epithelial cell differentiation [GO:0030855]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phospholipase inhibitor activity [GO:0004859]
d1ao0b1_d1xtug___1			Firmicutes	Crenarchaeota	4 iron, 4 sulfur cluster binding [GO:0051539]; amidophosphoribosyltransferase activity [GO:0004044]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]			4 iron, 4 sulfur cluster binding [GO:0051539]; amidophosphoribosyltransferase activity [GO:0004044]; magnesium ion binding [GO:0000287]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]
d1ao0b1_d4lygb1__1		Metazoa	Firmicutes	Chordata	4 iron, 4 sulfur cluster binding [GO:0051539]; amidophosphoribosyltransferase activity [GO:0004044]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]	4 iron, 4 sulfur cluster binding [GO:0051539]; amidophosphoribosyltransferase activity [GO:0004044]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]
d1ao6a1_d2vdba1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1ao6a2_d5orfc1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d1ao6b1_d5id7a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1ao7b2_d1j05l___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ao7d__d5f7wd1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ao8a__d3fyvx___1			Firmicutes	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d1aoaa1_d2r0oa1__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; bone development [GO:0060348]	brush border [GO:0005903]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; neuron projection [GO:0043005]; nuclear body [GO:0016604]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; pseudopodium [GO:0031143]; ribonucleoprotein complex [GO:1990904]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor transcription coactivator activity [GO:0030374]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; retinoic acid receptor binding [GO:0042974]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; actin filament bundle assembly [GO:0051017]; bicellular tight junction assembly [GO:0070830]; negative regulation of cellular component movement [GO:0051271]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; platelet degranulation [GO:0002576]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular component movement [GO:0051272]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pinocytosis [GO:0048549]; positive regulation of sodium:proton antiporter activity [GO:0032417]; protein localization to bicellular tight junction [GO:1902396]; protein transport [GO:0015031]; regulation of apoptotic process [GO:0042981]; regulation of nucleic acid-templated transcription [GO:1903506]; response to hypoxia [GO:0001666]; retinoic acid receptor signaling pathway [GO:0048384]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vesicle transport along actin filament [GO:0030050]	actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; bone development [GO:0060348]	actin filament bundle assembly [GO:0051017]; bicellular tight junction assembly [GO:0070830]; negative regulation of cellular component movement [GO:0051271]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; platelet degranulation [GO:0002576]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular component movement [GO:0051272]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pinocytosis [GO:0048549]; positive regulation of sodium:proton antiporter activity [GO:0032417]; protein localization to bicellular tight junction [GO:1902396]; protein transport [GO:0015031]; regulation of apoptotic process [GO:0042981]; regulation of nucleic acid-templated transcription [GO:1903506]; response to hypoxia [GO:0001666]; retinoic acid receptor signaling pathway [GO:0048384]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vesicle transport along actin filament [GO:0030050]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	brush border [GO:0005903]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; neuron projection [GO:0043005]; nuclear body [GO:0016604]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; pseudopodium [GO:0031143]; ribonucleoprotein complex [GO:1990904]; stress fiber [GO:0001725]; Z disc [GO:0030018]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor transcription coactivator activity [GO:0030374]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; retinoic acid receptor binding [GO:0042974]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]
d1aoaa2_d3hocb2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; bone development [GO:0060348]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; bone development [GO:0060348]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d1aoda__d3ea2a___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]; pathogenesis [GO:0009405]	lipid catabolic process [GO:0016042]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]
d1aofa2_d1n90b2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1aofb1_d3o1ya___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]		apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	periplasmic space [GO:0042597]	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1aoig__d5x7xh___1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; DNA-templated transcription, initiation [GO:0006352]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	DNA-templated transcription, initiation [GO:0006352]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleosome [GO:0000786]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1aoka__d1tk4a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; host cell postsynaptic membrane [GO:0035792]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; host cell postsynaptic membrane [GO:0035792]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1aonc2_d1xckb3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]
d1aonf2_d5cdjb___1		Viridiplantae	Proteobacteria	Chlorophyta	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	chloroplast [GO:0009507]; ATP binding [GO:0005524]; protein refolding [GO:0042026]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	protein refolding [GO:0042026]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]	chloroplast [GO:0009507]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]
d1aonn2_d1a6eb2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1aons__d1p3hk___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; zymogen binding [GO:0035375]; cellular response to heat [GO:0034605]; chaperone cofactor-dependent protein refolding [GO:0051085]; regulation of transcription, DNA-templated [GO:0006355]; response to antibiotic [GO:0046677]; response to heat [GO:0009408]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	cellular response to heat [GO:0034605]; chaperone cofactor-dependent protein refolding [GO:0051085]; regulation of transcription, DNA-templated [GO:0006355]; response to antibiotic [GO:0046677]; response to heat [GO:0009408]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; zymogen binding [GO:0035375]
d1aonu__d1p3hf___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; zymogen binding [GO:0035375]; cellular response to heat [GO:0034605]; chaperone cofactor-dependent protein refolding [GO:0051085]; regulation of transcription, DNA-templated [GO:0006355]; response to antibiotic [GO:0046677]; response to heat [GO:0009408]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	cellular response to heat [GO:0034605]; chaperone cofactor-dependent protein refolding [GO:0051085]; regulation of transcription, DNA-templated [GO:0006355]; response to antibiotic [GO:0046677]; response to heat [GO:0009408]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; zymogen binding [GO:0035375]
d1aoqb1_d1mg2p___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1aoxb__d3zqkb___1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha2-beta1 complex [GO:0034666]; integrin complex [GO:0008305]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; collagen receptor activity [GO:0038064]; heparan sulfate proteoglycan binding [GO:0043395]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; virus receptor activity [GO:0001618]; animal organ morphogenesis [GO:0009887]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell population proliferation [GO:0008283]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; collagen-activated signaling pathway [GO:0038065]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; focal adhesion assembly [GO:0048041]; hepatocyte differentiation [GO:0070365]; hypotonic response [GO:0006971]; integrin-mediated signaling pathway [GO:0007229]; mammary gland development [GO:0030879]; mesodermal cell differentiation [GO:0048333]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell projection organization [GO:0031346]; positive regulation of collagen binding [GO:0033343]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of translation [GO:0045727]; positive regulation of transmission of nerve impulse [GO:0051971]; response to amine [GO:0014075]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to L-ascorbic acid [GO:0033591]; response to muscle activity [GO:0014850]; response to parathyroid hormone [GO:0071107]; skin morphogenesis [GO:0043589]; substrate-dependent cell migration [GO:0006929]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	animal organ morphogenesis [GO:0009887]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell population proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; collagen-activated signaling pathway [GO:0038065]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; focal adhesion assembly [GO:0048041]; hepatocyte differentiation [GO:0070365]; hypotonic response [GO:0006971]; integrin-mediated signaling pathway [GO:0007229]; mammary gland development [GO:0030879]; mesodermal cell differentiation [GO:0048333]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell projection organization [GO:0031346]; positive regulation of collagen binding [GO:0033343]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of translation [GO:0045727]; positive regulation of transmission of nerve impulse [GO:0051971]; response to amine [GO:0014075]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to L-ascorbic acid [GO:0033591]; response to muscle activity [GO:0014850]; response to parathyroid hormone [GO:0071107]; skin morphogenesis [GO:0043589]; substrate-dependent cell migration [GO:0006929]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	axon terminus [GO:0043679]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha2-beta1 complex [GO:0034666]; integrin complex [GO:0008305]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	amyloid-beta binding [GO:0001540]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; collagen receptor activity [GO:0038064]; heparan sulfate proteoglycan binding [GO:0043395]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; virus receptor activity [GO:0001618]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d1aoxb__d5hgjb___1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha2-beta1 complex [GO:0034666]; integrin complex [GO:0008305]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; collagen receptor activity [GO:0038064]; heparan sulfate proteoglycan binding [GO:0043395]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; virus receptor activity [GO:0001618]; animal organ morphogenesis [GO:0009887]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell population proliferation [GO:0008283]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; collagen-activated signaling pathway [GO:0038065]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; focal adhesion assembly [GO:0048041]; hepatocyte differentiation [GO:0070365]; hypotonic response [GO:0006971]; integrin-mediated signaling pathway [GO:0007229]; mammary gland development [GO:0030879]; mesodermal cell differentiation [GO:0048333]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell projection organization [GO:0031346]; positive regulation of collagen binding [GO:0033343]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of translation [GO:0045727]; positive regulation of transmission of nerve impulse [GO:0051971]; response to amine [GO:0014075]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to L-ascorbic acid [GO:0033591]; response to muscle activity [GO:0014850]; response to parathyroid hormone [GO:0071107]; skin morphogenesis [GO:0043589]; substrate-dependent cell migration [GO:0006929]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; integrin complex [GO:0008305]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell-matrix adhesion [GO:0007160]; cellular extravasation [GO:0045123]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; muscle contraction [GO:0006936]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	animal organ morphogenesis [GO:0009887]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell population proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; collagen-activated signaling pathway [GO:0038065]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; focal adhesion assembly [GO:0048041]; hepatocyte differentiation [GO:0070365]; hypotonic response [GO:0006971]; integrin-mediated signaling pathway [GO:0007229]; mammary gland development [GO:0030879]; mesodermal cell differentiation [GO:0048333]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell projection organization [GO:0031346]; positive regulation of collagen binding [GO:0033343]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of translation [GO:0045727]; positive regulation of transmission of nerve impulse [GO:0051971]; response to amine [GO:0014075]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to L-ascorbic acid [GO:0033591]; response to muscle activity [GO:0014850]; response to parathyroid hormone [GO:0071107]; skin morphogenesis [GO:0043589]; substrate-dependent cell migration [GO:0006929]	activation of MAPK activity [GO:0000187]; cell-matrix adhesion [GO:0007160]; cellular extravasation [GO:0045123]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; muscle contraction [GO:0006936]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	axon terminus [GO:0043679]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha2-beta1 complex [GO:0034666]; integrin complex [GO:0008305]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; integrin complex [GO:0008305]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; collagen receptor activity [GO:0038064]; heparan sulfate proteoglycan binding [GO:0043395]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; virus receptor activity [GO:0001618]	collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]
d1aoya__d1b4ac1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1aoza1_d3ablb2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]		ATP synthesis coupled electron transport [GO:0042773]	extracellular region [GO:0005576]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1aoza2_d3ugea___1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	extracellular region [GO:0005576]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1aozb2_d3sbrd2__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]		copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	extracellular region [GO:0005576]	membrane [GO:0016020]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d1ap2a__d1ad0b2__1												
d1ap2d__d3kynb1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ap5a2_d4yioa2__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ap5b1_d4l2aa1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ap5b2_d2goja2__1	Metazoa		Chordata	Apicomplexa	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ap7a__d3eu9a1__1	Metazoa	Metazoa	Chordata	Chordata	cyclin D2-CDK4 complex [GO:0097129]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]; autophagic cell death [GO:0048102]; cell cycle arrest [GO:0007050]; DNA synthesis involved in DNA repair [GO:0000731]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of phosphorylation [GO:0042326]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to retinoic acid [GO:0032526]; response to UV [GO:0009411]; response to vitamin D [GO:0033280]; sensory perception of sound [GO:0007605]	aggresome [GO:0016235]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle membrane [GO:0030659]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; presynaptic membrane [GO:0042734]; identical protein binding [GO:0042802]; magnesium ion transmembrane transporter activity [GO:0015095]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; lipoprotein transport [GO:0042953]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345]	autophagic cell death [GO:0048102]; cell cycle arrest [GO:0007050]; DNA synthesis involved in DNA repair [GO:0000731]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of phosphorylation [GO:0042326]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to retinoic acid [GO:0032526]; response to UV [GO:0009411]; response to vitamin D [GO:0033280]; sensory perception of sound [GO:0007605]	lipoprotein transport [GO:0042953]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345]	cyclin D2-CDK4 complex [GO:0097129]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	aggresome [GO:0016235]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle membrane [GO:0030659]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; presynaptic membrane [GO:0042734]	cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]	identical protein binding [GO:0042802]; magnesium ion transmembrane transporter activity [GO:0015095]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]
d1apba__d2gx6a___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; ATPase-coupled monosaccharide transmembrane transporter activity [GO:0015407]; monosaccharide binding [GO:0048029]; L-arabinose transmembrane transport [GO:0042882]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; monosaccharide binding [GO:0048029]; D-ribose transmembrane transport [GO:0015752]; positive chemotaxis [GO:0050918]	L-arabinose transmembrane transport [GO:0042882]	D-ribose transmembrane transport [GO:0015752]; positive chemotaxis [GO:0050918]	outer membrane-bounded periplasmic space [GO:0030288]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	ATPase-coupled monosaccharide transmembrane transporter activity [GO:0015407]; monosaccharide binding [GO:0048029]	monosaccharide binding [GO:0048029]
d1apca__d3c62c___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1apsa__d2hfnj___1	Metazoa		Chordata	Cyanobacteria	acylphosphatase activity [GO:0003998]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]					acylphosphatase activity [GO:0003998]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]
d1apve__d1odyb___1	Fungi		Ascomycota		extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	extracellular region [GO:0005576]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1apxa__d1cx2c1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cytoplasm [GO:0005737]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1apxb__d3wxoa2__1	Viridiplantae		Streptophyta	Cyanobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]		heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1aq0a__d1hp5a1__1	Viridiplantae		Streptophyta	Actinobacteria	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			licheninase activity [GO:0042972]	beta-N-acetylhexosaminidase activity [GO:0004563]
d1aq2a2_d4ywda1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	gluconeogenesis [GO:0006094]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]
d1aq6b__d3wk8a1__1		Metazoa	Proteobacteria	Chordata	(S)-2-haloacid dehalogenase activity [GO:0018784]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	(S)-2-haloacid dehalogenase activity [GO:0018784]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d1aq8b2_d3ppsb1__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1aqdd1_d4l8sb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]	
d1aqdd2_d4z7ub1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	nutrient reservoir activity [GO:0045735]	antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]	nutrient reservoir activity [GO:0045735]
d1aqde1_d1sjxa1__1	Metazoa		Chordata		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]	
d1aqdg1_d1n64l2__1	Metazoa		Chordata		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1aqdh1_d5j75b1__1	Metazoa		Chordata		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]	
d1aqdh2_d1s7wg2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1aqfd3_d2vgic3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	positive regulation of sprouting angiogenesis [GO:1903672]	ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1aqfe3_d2vgia3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	positive regulation of sprouting angiogenesis [GO:1903672]	ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1aqfg3_d2g50d3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	positive regulation of sprouting angiogenesis [GO:1903672]	positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1aqjb2_d1aqia2__1			Deinococcus-Thermus	Deinococcus-Thermus	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]
d1aqkh2_d4kk8f2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1aqma2_d1hvqa___1		Viridiplantae	Proteobacteria	Streptophyta	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	vacuole [GO:0005773]; chitinase activity [GO:0004568]; lysozyme activity [GO:0003796]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	vacuole [GO:0005773]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	chitinase activity [GO:0004568]; lysozyme activity [GO:0003796]
d1aqma2_d1wdpa___1		Viridiplantae	Proteobacteria	Streptophyta	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d1aqva1_d4pnfg2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d1aqva2_d3ik7a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1aqvb1_d5gzze2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d1aqvb2_d1gumc2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1aqvb2_d1tp9c___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1aqwa2_d2vo4a1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d1aqwb1_d3gh6a2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d1aqwd1_d4iw9a2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	
d1aqwd2_d1axdb2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1aqxa1_d2hnlb2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d1aqxb1_d2x64f2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	transferase activity [GO:0016740]
d1aqxb2_d4j56f1__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; cytosol [GO:0005829]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	protein disulfide oxidoreductase activity [GO:0015035]
d1aqxc1_d1vf4a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d1ar0a__d3ujmb1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; precatalytic spliceosome [GO:0071011]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; compound eye photoreceptor fate commitment [GO:0001752]; dorsal/ventral axis specification, ovarian follicular epithelium [GO:0008069]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of imaginal disc growth [GO:0045571]; ommatidial rotation [GO:0016318]; positive regulation of gene expression [GO:0010628]; Ras protein signal transduction [GO:0007265]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	compound eye photoreceptor fate commitment [GO:0001752]; dorsal/ventral axis specification, ovarian follicular epithelium [GO:0008069]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of imaginal disc growth [GO:0045571]; ommatidial rotation [GO:0016318]; positive regulation of gene expression [GO:0010628]; Ras protein signal transduction [GO:0007265]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; precatalytic spliceosome [GO:0071011]; ribonucleoprotein complex [GO:1990904]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	mRNA binding [GO:0003729]
d1ar1b1_d1ocro1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	ATP synthesis coupled electron transport [GO:0042773]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1ar1b1_d2bhfa3__1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	sporulation resulting in formation of a cellular spore [GO:0030435]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	outer membrane-bounded periplasmic space [GO:0030288]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1ar1c__d1c12a2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ar4b1_d4jyya1__1			Actinobacteria	Firmicutes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ar71__d1f8v.3__1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]
d1ar73__d1yc6p___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1arga__d2bwoa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]; protoporphyrinogen IX biosynthetic process [GO:0006782]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]
d1arla__d4mria___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	cytosol [GO:0005829]; nucleus [GO:0005634]; aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	proteolysis [GO:0006508]	aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	extracellular space [GO:0005615]	cytosol [GO:0005829]; nucleus [GO:0005634]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1arma__d4z65a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1arpa__d1cqea1__1	Fungi	Metazoa	Basidiomycota	Chordata	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1arta__d1yiya1__1		Metazoa	Proteobacteria	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	kynurenine aminotransferase activity [GO:0036137]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	kynurenine aminotransferase activity [GO:0036137]; pyridoxal phosphate binding [GO:0030170]
d1arua__d1eqgb1__1	Fungi	Metazoa	Basidiomycota	Chordata	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1as3a1_d1tada1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	G protein-coupled receptor complex [GO:0097648]; heterotrimeric G-protein complex [GO:0005834]; photoreceptor connecting cilium [GO:0032391]; photoreceptor disc membrane [GO:0097381]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment membrane [GO:0042622]; acyl binding [GO:0000035]; G protein-coupled receptor binding [GO:0001664]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; detection of light stimulus involved in visual perception [GO:0050908]; eye photoreceptor cell development [GO:0042462]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; phototransduction [GO:0007602]; phototransduction, visible light [GO:0007603]; response to light stimulus [GO:0009416]; retina development in camera-type eye [GO:0060041]; sensory perception of umami taste [GO:0050917]	adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; detection of light stimulus involved in visual perception [GO:0050908]; eye photoreceptor cell development [GO:0042462]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; phototransduction [GO:0007602]; phototransduction, visible light [GO:0007603]; response to light stimulus [GO:0009416]; retina development in camera-type eye [GO:0060041]; sensory perception of umami taste [GO:0050917]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	G protein-coupled receptor complex [GO:0097648]; heterotrimeric G-protein complex [GO:0005834]; photoreceptor connecting cilium [GO:0032391]; photoreceptor disc membrane [GO:0097381]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment membrane [GO:0042622]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	acyl binding [GO:0000035]; GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]
d1as6a1_d2jl3b1__1			Proteobacteria		periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	
d1as6b1_d1ibya___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	metal ion binding [GO:0046872]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	metal ion binding [GO:0046872]
d1as6b1_d5b1jb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1as7a2_d1hawa2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1as7a2_d3nyka___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1as7b1_d1m57h1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1as7b2_d3abko2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1as7c1_d1kbvf2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]	cell outer membrane [GO:0009279]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1as8a1_d1tsbc___1			Proteobacteria		periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	
d1as8a2_d2hxab___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1as8c2_d1kgye___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]	periplasmic space [GO:0042597]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1asca__d1i43c___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d1asha__d4po5a1__1	Metazoa		Nematoda (roundworms)	Cyanobacteria	extracellular space [GO:0005615]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	extracellular space [GO:0005615]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1aska__d5bxqb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]
d1askb__d4xbtc1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	limonene-1,2-epoxide hydrolase activity [GO:0018744]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]		cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]		identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d1asla__d1b4xa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1aslb__d1dtya___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	biotin biosynthetic process [GO:0009102]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]
d1asmb__d1eqbc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytosol [GO:0005829]; membrane [GO:0016020]; amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]; cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]
d1asna__d3a8ux___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]
d1asob1_d1mg3c___1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			extracellular region [GO:0005576]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1asob2_d4ko7b___1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	extracellular region [GO:0005576]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1asob3_d2wsda2__1	Viridiplantae		Streptophyta	Firmicutes	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1aspa2_d1as8b2__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	extracellular region [GO:0005576]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1aspa3_d1rzpb2__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	extracellular region [GO:0005576]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1aspb2_d2fjsc2__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	extracellular region [GO:0005576]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1aspb3_d5b7ma2__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	extracellular region [GO:0005576]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d1asqa2_d1pmya___1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			extracellular region [GO:0005576]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1asqa3_d1gs6x2__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	extracellular region [GO:0005576]		copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1asqb2_d1w6wa2__1	Viridiplantae		Streptophyta	Firmicutes	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1asya1_d1bbua1__1	Fungi		Ascomycota	Proteobacteria	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	aspartyl-tRNA aminoacylation [GO:0006422]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytosol [GO:0005829]; membrane [GO:0016020]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]
d1asyb1_d1pybc___1	Fungi		Ascomycota	Aquificae	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; methionyl-tRNA aminoacylation [GO:0006431]	aspartyl-tRNA aminoacylation [GO:0006422]	methionyl-tRNA aminoacylation [GO:0006431]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]
d1aszb1_d1e24a1__1	Fungi		Ascomycota	Proteobacteria	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	aspartyl-tRNA aminoacylation [GO:0006422]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytosol [GO:0005829]; membrane [GO:0016020]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]
d1aszb1_d2qowq1__1	Fungi		Ascomycota		aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]		aspartyl-tRNA aminoacylation [GO:0006422]		aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]	
d1aszb2_d1nyqb4__1	Fungi		Ascomycota	Firmicutes	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]	aspartyl-tRNA aminoacylation [GO:0006422]	threonyl-tRNA aminoacylation [GO:0006435]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]
d1atjf__d5syla2__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1atlb__d1wnia___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; collagen catabolic process [GO:0030574]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	collagen catabolic process [GO:0030574]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1atlb__d4h49b1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; collagen catabolic process [GO:0030574]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen catabolic process [GO:0030574]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1atsa2_d3cjaa1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adenosine-diphosphatase activity [GO:0043262]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	adenosine-diphosphatase activity [GO:0043262]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]
d1atzb__d3f78c___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]
d1au8a__d5c1ub1__1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; angiotensin maturation [GO:0002003]; antibacterial humoral response [GO:0019731]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of gram-positive bacterium [GO:0070946]; positive regulation of immune response [GO:0050778]; protein phosphorylation [GO:0006468]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	angiotensin maturation [GO:0002003]; antibacterial humoral response [GO:0019731]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of gram-positive bacterium [GO:0070946]; positive regulation of immune response [GO:0050778]; protein phosphorylation [GO:0006468]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	azurophil granule lumen [GO:0035578]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	heparin binding [GO:0008201]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1auaa2_d3b7qb2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; phosphatidylcholine transporter activity [GO:0008525]; phosphatidylinositol transfer activity [GO:0008526]; ascospore formation [GO:0030437]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to vacuole transport [GO:0006896]; Golgi vesicle budding [GO:0048194]; negative regulation of phosphatidylcholine biosynthetic process [GO:2001246]; negative regulation of phosphatidylglycerol biosynthetic process [GO:1901352]; phosphatidylinositol metabolic process [GO:0046488]; phospholipid transport [GO:0015914]	nucleus [GO:0005634]; phosphatidylcholine binding [GO:0031210]; phosphatidylinositol binding [GO:0035091]	ascospore formation [GO:0030437]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to vacuole transport [GO:0006896]; Golgi vesicle budding [GO:0048194]; negative regulation of phosphatidylcholine biosynthetic process [GO:2001246]; negative regulation of phosphatidylglycerol biosynthetic process [GO:1901352]; phosphatidylinositol metabolic process [GO:0046488]; phospholipid transport [GO:0015914]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]	nucleus [GO:0005634]	phosphatidylcholine transporter activity [GO:0008525]; phosphatidylinositol transfer activity [GO:0008526]	phosphatidylcholine binding [GO:0031210]; phosphatidylinositol binding [GO:0035091]
d1auob__d1yaje1__1		Metazoa	Proteobacteria	Chordata	methyl indole-3-acetate esterase activity [GO:0080030]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	methyl indole-3-acetate esterase activity [GO:0080030]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d1aupa2_d4a26a1__1			Firmicutes		glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; kinetoplast [GO:0020023]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; tetrahydrofolate interconversion [GO:0035999]	cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	tetrahydrofolate interconversion [GO:0035999]		cytosol [GO:0005829]; kinetoplast [GO:0020023]	glutamate dehydrogenase (NAD+) activity [GO:0004352]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]
d1ausl2_d5hane1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1auso2_d5haof1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1ausv__d1uzhc1__1	Viridiplantae	Viridiplantae	Streptophyta	Chlorophyta	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1autc__d3t28a___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of coagulation [GO:0050819]; negative regulation of inflammatory response [GO:0050728]; positive regulation of establishment of endothelial barrier [GO:1903142]; post-translational protein modification [GO:0043687]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of coagulation [GO:0050819]; negative regulation of inflammatory response [GO:0050728]; positive regulation of establishment of endothelial barrier [GO:1903142]; post-translational protein modification [GO:0043687]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1auwa__d1hy1b___1	Metazoa	Metazoa	Chordata	Chordata	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]			argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]
d1auwa__d4adld___1	Metazoa		Chordata	Actinobacteria	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; tricarboxylic acid cycle enzyme complex [GO:0045239]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]	fumarate hydratase activity [GO:0004333]
d1auwd__d1gk2d___1	Metazoa		Chordata	Proteobacteria	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	cytoplasm [GO:0005737]; histidine ammonia-lyase activity [GO:0004397]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]		cytoplasm [GO:0005737]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]	histidine ammonia-lyase activity [GO:0004397]
d1av5a__d5ipcb___1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d1avac__d4h9wa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]	serine-type endopeptidase inhibitor activity [GO:0004867]					alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1avad__d1diwa2__1	Viridiplantae		Streptophyta	Firmicutes	alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1avad__d2iwtb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]	alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]	protein disulfide oxidoreductase activity [GO:0015035]
d1avbb__d1slcb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; nutrient reservoir activity [GO:0045735]; toxin activity [GO:0090729]; defense response [GO:0006952]	extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]; apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	defense response [GO:0006952]	apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]		extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; nutrient reservoir activity [GO:0045735]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]
d1avf.1_d2ikoa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; positive regulation of antibacterial peptide production [GO:0002803]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	digestion [GO:0007586]; positive regulation of antibacterial peptide production [GO:0002803]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	extracellular space [GO:0005615]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d1avg.1_d1gbma___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1avhb__d1aeid___1	Metazoa	Metazoa	Chordata	Cnidaria	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]		calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]
d1avla2_d1a2vf2__1		Fungi	Actinobacteria	Ascomycota	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	peroxisome [GO:0005777]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]		peroxisome [GO:0005777]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d1avma1_d4jz2a1__1			Actinobacteria	Firmicutes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1avma2_d1xuqb2__1			Actinobacteria	Firmicutes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]			metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1avma2_d3sdpa2__1			Actinobacteria	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1avmb1_d4gund1__1		Fungi	Actinobacteria	Ascomycota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1avmb2_d3ak1b2__1			Actinobacteria	Crenarchaeota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1avqc__d1eyua___1				Proteobacteria	exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]		DNA restriction-modification system [GO:0009307]			exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]
d1avsa__d3gk2a___1	Metazoa	Metazoa	Chordata	Chordata	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	troponin complex [GO:0005861]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1avsb__d1xk4d___1	Metazoa	Metazoa	Chordata	Chordata	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	troponin complex [GO:0005861]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1avwa__d5esba1__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; transformation of host cell by virus [GO:0019087]	digestion [GO:0007586]; proteolysis [GO:0006508]	transformation of host cell by virus [GO:0019087]	extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d1avxa__d2alva1__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1aw0a__d3dxsx___1	Metazoa	Viridiplantae	Chordata	Streptophyta	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]; antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; trans-Golgi network [GO:0005802]; ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; ethylene-activated signaling pathway [GO:0009873]; regulation of stomatal movement [GO:0010119]; response to ethylene [GO:0009723]	antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	ethylene-activated signaling pathway [GO:0009873]; regulation of stomatal movement [GO:0010119]; response to ethylene [GO:0009723]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; trans-Golgi network [GO:0005802]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]	ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]
d1aw1b__d4zvjb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	triose-phosphate isomerase activity [GO:0004807]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]
d1aw2k__d1ypia___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1aw3a__d1x3xb___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; response to cadmium ion [GO:0046686]	metal ion binding [GO:0046872]	response to cadmium ion [GO:0046686]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]		electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1aw8.1_d1uhd.1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aspartate 1-decarboxylase activity [GO:0004068]; alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	cytoplasm [GO:0005737]; aspartate 1-decarboxylase activity [GO:0004068]; alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]	alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	aspartate 1-decarboxylase activity [GO:0004068]	aspartate 1-decarboxylase activity [GO:0004068]
d1aw8.2_d4kodd1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; aspartate 1-decarboxylase activity [GO:0004068]; alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	cytosol [GO:0005829]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	aspartate 1-decarboxylase activity [GO:0004068]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1aw9a1_d3lfla2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	protein-containing complex [GO:0032991]; drug binding [GO:0008144]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; response to herbicide [GO:0009635]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	response to herbicide [GO:0009635]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	drug binding [GO:0008144]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d1aw9a1_d5ecqb2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	protein-containing complex [GO:0032991]; drug binding [GO:0008144]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; response to herbicide [GO:0009635]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	response to herbicide [GO:0009635]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	protein-containing complex [GO:0032991]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	drug binding [GO:0008144]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1awda__d3sr6a1__1	Viridiplantae	Metazoa	Chlorophyta	Chordata	chloroplast [GO:0009507]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]	chloroplast [GO:0009507]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1awf.1_d2h2za___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1awpa__d1euea___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1awpb__d1b5ba___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; response to cadmium ion [GO:0046686]		response to cadmium ion [GO:0046686]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1awva__d4i9yb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	annulate lamellae [GO:0005642]; cytoplasm [GO:0005737]; cytoplasmic periphery of the nuclear pore complex [GO:1990723]; cytosol [GO:0005829]; host cell [GO:0043657]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear inclusion body [GO:0042405]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear pore cytoplasmic filaments [GO:0044614]; nuclear pore nuclear basket [GO:0044615]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; centrosome localization [GO:0051642]; intracellular transport of virus [GO:0075733]; mRNA export from nucleus [GO:0006406]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of GTPase activity [GO:0043547]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of gene silencing by miRNA [GO:0060964]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110]; response to amphetamine [GO:0001975]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	centrosome localization [GO:0051642]; intracellular transport of virus [GO:0075733]; mRNA export from nucleus [GO:0006406]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of GTPase activity [GO:0043547]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of gene silencing by miRNA [GO:0060964]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110]; response to amphetamine [GO:0001975]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	annulate lamellae [GO:0005642]; cytoplasm [GO:0005737]; cytoplasmic periphery of the nuclear pore complex [GO:1990723]; cytosol [GO:0005829]; host cell [GO:0043657]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear inclusion body [GO:0042405]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear pore cytoplasmic filaments [GO:0044614]; nuclear pore nuclear basket [GO:0044615]; nucleus [GO:0005634]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]
d1awvc__d1qnga___1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1awza__d4peqc___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	extracellular region [GO:0005576]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1ax0a__d4atfd1__1	Viridiplantae		Streptophyta	Bacteroidetes	carbohydrate binding [GO:0030246]	cell outer membrane [GO:0009279]; beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		cell outer membrane [GO:0009279]	carbohydrate binding [GO:0030246]	beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]
d1ax1a__d2d3rd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1ax2a__d5hxvg___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]
d1axab__d5p8ia___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1axce1_d6amsa3__1	Metazoa		Chordata	Proteobacteria	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA strand elongation involved in DNA replication [GO:0006271]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	DNA strand elongation involved in DNA replication [GO:0006271]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1axda2_d5abrb___1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; nitrogen fixation [GO:0009399]; oxidation-reduction process [GO:0055114]	glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	nitrogen fixation [GO:0009399]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]		glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]
d1axea2_d1f8fa2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]; zinc ion binding [GO:0008270]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]; zinc ion binding [GO:0008270]
d1axfb__d2gtlk1__1		Metazoa		Annelida		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d1axfc__d3uhia___1		Metazoa		Mollusca		cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1axga2_d1llub2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]
d1axgd2_d1qv7b2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]	cytosol [GO:0005829]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1axib2_d5dftf___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth hormone receptor complex [GO:0070195]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; growth hormone receptor activity [GO:0004903]; identical protein binding [GO:0042802]; peptide hormone binding [GO:0017046]; proline-rich region binding [GO:0070064]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; activation of Janus kinase activity [GO:0042976]; activation of MAPK activity [GO:0000187]; cellular response to hormone stimulus [GO:0032870]; endocytosis [GO:0006897]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; hormone metabolic process [GO:0042445]; insulin-like growth factor receptor signaling pathway [GO:0048009]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; receptor internalization [GO:0031623]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of multicellular organism growth [GO:0040014]; response to cycloheximide [GO:0046898]; response to estradiol [GO:0032355]; taurine metabolic process [GO:0019530]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	activation of Janus kinase activity [GO:0042976]; activation of MAPK activity [GO:0000187]; cellular response to hormone stimulus [GO:0032870]; endocytosis [GO:0006897]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; hormone metabolic process [GO:0042445]; insulin-like growth factor receptor signaling pathway [GO:0048009]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; receptor internalization [GO:0031623]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of multicellular organism growth [GO:0040014]; response to cycloheximide [GO:0046898]; response to estradiol [GO:0032355]; taurine metabolic process [GO:0019530]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	cell surface [GO:0009986]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth hormone receptor complex [GO:0070195]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; growth hormone receptor activity [GO:0004903]; identical protein binding [GO:0042802]; peptide hormone binding [GO:0017046]; proline-rich region binding [GO:0070064]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]
d1axsb1_d3e6fa2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1axth1_d5ddhb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1axtl2_d3oska___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1axtl2_d3pwna2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ay0a1_d1qgda2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	pentose-phosphate shunt [GO:0006098]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d1ay0a1_d5d6rm1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; butanediol metabolic process [GO:0034077]	pentose-phosphate shunt [GO:0006098]	butanediol metabolic process [GO:0034077]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1ay0a2_d1itzb2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	pentose-phosphate shunt [GO:0006098]	pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]
d1ay0b2_d1yhya2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	pentose-phosphate shunt [GO:0006098]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1ay0b3_d1itza3__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	pentose-phosphate shunt [GO:0006098]	pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]
d1ay0b3_d3exgf2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	pentose-phosphate shunt [GO:0006098]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1ay1h2_d4hija1__1												
d1ay5a__d1u08a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]; aromatic amino acid family biosynthetic process [GO:0009073]	cytoplasm [GO:0005737]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; methionine-oxo-acid transaminase activity [GO:0010326]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	aromatic amino acid family biosynthetic process [GO:0009073]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]	kynurenine-oxoglutarate transaminase activity [GO:0016212]; methionine-oxo-acid transaminase activity [GO:0010326]; pyridoxal phosphate binding [GO:0030170]
d1ay5a__d4b98b___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]; aromatic amino acid family biosynthetic process [GO:0009073]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]; beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	aromatic amino acid family biosynthetic process [GO:0009073]	beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	cytoplasm [GO:0005737]		L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]
d1ay7a__d1bvia___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1ay8a__d1qira___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]; aromatic amino acid family biosynthetic process [GO:0009073]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	aromatic amino acid family biosynthetic process [GO:0009073]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1ayfa__d1kfyn2__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1ayfb__d1xlqc___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1ayfb__d2wu5j1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d1ayka__d1os9a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1ayla2_d2rk8a1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	gluconeogenesis [GO:0006094]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]
d1ayla2_d4wpua1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; gluconeogenesis [GO:0006094]	gluconeogenesis [GO:0006094]	gluconeogenesis [GO:0006094]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]	GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]
d1ayn1__d1al21___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ayn1__d1js9a___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1ayn3__d4pdwc___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ayn3__d4y5zl___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1aypa__d4ntxc___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]; antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	integral component of plasma membrane [GO:0005887]; acid-sensing ion channel activity [GO:0044736]; identical protein binding [GO:0042802]; cellular response to pH [GO:0071467]; protein homotrimerization [GO:0070207]; sodium ion transmembrane transport [GO:0035725]	antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	cellular response to pH [GO:0071467]; protein homotrimerization [GO:0070207]; sodium ion transmembrane transport [GO:0035725]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]	integral component of plasma membrane [GO:0005887]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]	acid-sensing ion channel activity [GO:0044736]; identical protein binding [GO:0042802]
d1aypd__d1zlba___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]; antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]; regulation of blood pressure [GO:0008217]	antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]; regulation of blood pressure [GO:0008217]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]	extracellular region [GO:0005576]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1ayrb1_d1imhd1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]; G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cytokine production [GO:0001816]; excretion [GO:0007588]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; response to osmotic stress [GO:0006970]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]	G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cytokine production [GO:0001816]; excretion [GO:0007588]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; response to osmotic stress [GO:0006970]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1ayrc2_d3ugua2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]; G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]; G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]	G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]
d1azba__d1asqb2__1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]			periplasmic space [GO:0042597]	extracellular region [GO:0005576]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]
d1azbb__d1azrb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1azbb__d2fqda1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d1azca__d2eilb1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]		ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1azcb__d5b3sb2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]		ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1azda__d3azzc___1	Viridiplantae		Streptophyta	Thermotogae	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1azdd__d2e51c___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1azdd__d6ekua3__1	Viridiplantae		Streptophyta	Proteobacteria	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]; ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]		ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]
d1azla__d3o2nb___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1azna__d4knsf2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1aznb__d2vw6a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1aznc__d4n2ga1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; chromatin-mediated maintenance of transcription [GO:0048096]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]	oxidation-reduction process [GO:0055114]	cellular response to leukemia inhibitory factor [GO:1990830]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin organization [GO:0006325]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]
d1aznd__d2i7sc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1azrc__d1dyza___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1azrc__d4yscb2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1azua__d2q5ba___1			Proteobacteria	Cyanobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	thylakoid membrane [GO:0042651]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1azva__d3gzoh___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1azwa__d1brta___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]	peroxidase activity [GO:0004601]; antibiotic biosynthetic process [GO:0017000]		antibiotic biosynthetic process [GO:0017000]	cytoplasm [GO:0005737]		aminopeptidase activity [GO:0004177]	peroxidase activity [GO:0004601]
d1azyb3_d4yeka3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]	cytosol [GO:0005829]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]	cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]	pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1azza__d4wmea___1			Proteobacteria		outer membrane-bounded periplasmic space [GO:0030288]; serine-type endopeptidase inhibitor activity [GO:0004867]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	outer membrane-bounded periplasmic space [GO:0030288]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase inhibitor activity [GO:0004867]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]
d1azzd__d1xxfc___1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; serine-type endopeptidase inhibitor activity [GO:0004867]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]		blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	outer membrane-bounded periplasmic space [GO:0030288]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	serine-type endopeptidase inhibitor activity [GO:0004867]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d1b06a1_d4f2ng1__1			Crenarchaeota		cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1b06a2_d4f2nd2__1			Crenarchaeota		cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1b06a2_d5t30b2__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1b06b2_d3ljfb2__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1b06c2_d4br6c2__1		Fungi	Crenarchaeota	Ascomycota	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1b06e2_d3ljfa2__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1b06f2_d2p4kb2__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1b09a__d5ej3a___1	Metazoa		Chordata	Actinobacteria	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; xylan catabolic process [GO:0045493]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]
d1b0ba__d3bj2c___1	Metazoa	Metazoa	Mollusca	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen transport [GO:0015671]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	oxygen transport [GO:0015671]		extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1b0da__d3cqlb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	vacuole [GO:0005773]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	vacuole [GO:0005773]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d1b0ea__d2wpks___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]
d1b0ea__d5dp7a1__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1b0ga1_d5h2bb2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1b0ga2_d5ujtg1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1b0ka2_d1fgha2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; metal ion binding [GO:0046872]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]
d1b0la1_d1lgbc___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d1b0ma1_d2pkpa___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; metal ion binding [GO:0046872]; tricarboxylic acid cycle [GO:0006099]	catalytic complex [GO:1902494]; aconitate hydratase activity [GO:0003994]; homoaconitate hydratase activity [GO:0004409]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; coenzyme B biosynthetic process [GO:0019298]	tricarboxylic acid cycle [GO:0006099]	coenzyme B biosynthetic process [GO:0019298]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	catalytic complex [GO:1902494]	4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; metal ion binding [GO:0046872]	aconitate hydratase activity [GO:0003994]; homoaconitate hydratase activity [GO:0004409]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]
d1b0oa__d4zhdb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]		antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1b0pa1_d2g1ib3__1			Proteobacteria		cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]		electron transport chain [GO:0022900]		cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	
d1b0rb2_d1i9rh1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]; activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]
d1b0ta__d1b0vc___1			Proteobacteria	Proteobacteria	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1b0wb__d4olvl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]	structural molecule activity [GO:0005198]
d1b10a__d2l1da1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	anchored component of membrane [GO:0031225]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of catalytic activity [GO:0043086]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization [GO:0032880]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to oxidative stress [GO:0006979]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of catalytic activity [GO:0043086]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization [GO:0032880]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to oxidative stress [GO:0006979]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	anchored component of membrane [GO:0031225]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; type 5 metabotropic glutamate receptor binding [GO:0031802]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d1b14a__d1qg6a___1	Metazoa		Arthropoda	Proteobacteria	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]; alcohol metabolic process [GO:0006066]	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	alcohol metabolic process [GO:0006066]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]; membrane [GO:0016020]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]
d1b14b__d1ntoh2__1	Metazoa		Arthropoda	Crenarchaeota	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]; alcohol metabolic process [GO:0006066]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	alcohol metabolic process [GO:0006066]				alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]
d1b15b__d5fffb___1	Metazoa	Viridiplantae	Arthropoda	Streptophyta	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]; alcohol metabolic process [GO:0006066]	oxidoreductase activity [GO:0016491]	alcohol metabolic process [GO:0006066]				alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]	oxidoreductase activity [GO:0016491]
d1b1ba1_d1f5ta1__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein dimerization activity [GO:0046983]; SH3 domain binding [GO:0017124]; transition metal ion binding [GO:0046914]; protein homooligomerization [GO:0051260]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]	protein homooligomerization [GO:0051260]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein dimerization activity [GO:0046983]; SH3 domain binding [GO:0017124]; transition metal ion binding [GO:0046914]
d1b1ba2_d1dpra2__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein dimerization activity [GO:0046983]; SH3 domain binding [GO:0017124]; transition metal ion binding [GO:0046914]; protein homooligomerization [GO:0051260]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]	protein homooligomerization [GO:0051260]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein dimerization activity [GO:0046983]; SH3 domain binding [GO:0017124]; transition metal ion binding [GO:0046914]
d1b1ca__d5eaif___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d1b1ha__d1n76a2__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	protein transport [GO:0015031]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	peptide transmembrane transporter activity [GO:1904680]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d1b1ua__d1s6da___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]	nutrient reservoir activity [GO:0045735]			extracellular region [GO:0005576]		alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]	nutrient reservoir activity [GO:0045735]
d1b1xa1_d1hslb___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	outer membrane-bounded periplasmic space [GO:0030288]; amino acid binding [GO:0016597]; amino acid transport [GO:0006865]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	amino acid transport [GO:0006865]	extracellular space [GO:0005615]; specific granule [GO:0042581]	outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]	amino acid binding [GO:0016597]
d1b1xa2_d1ce2a2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	extracellular space [GO:0005615]; specific granule [GO:0042581]; iron ion binding [GO:0005506]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	extracellular space [GO:0005615]; specific granule [GO:0042581]	extracellular space [GO:0005615]; specific granule [GO:0042581]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]	iron ion binding [GO:0005506]; serine-type endopeptidase activity [GO:0004252]
d1b1xa2_d5tu0a___1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]		extracellular space [GO:0005615]; specific granule [GO:0042581]	plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]	carbohydrate transmembrane transporter activity [GO:0015144]
d1b1za2_d3r2tb2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1b1zc2_d3gp7a2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1b1zd1_d4fo2n___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1b1zd2_d1enfa2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1b21a__d1b20a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1b21b__d3dh2d___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1b23p2_d1efcb2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1b26a2_d1lu9a2__1			Thermotogae	Proteobacteria	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	cellular amino acid metabolic process [GO:0006520]	formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]		cytoplasm [GO:0005737]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]
d1b26b2_d3toza1__1			Thermotogae	Firmicutes	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1b26e1_d1i3lb___1		Metazoa	Thermotogae	Chordata	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]	cellular amino acid metabolic process [GO:0006520]	galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]		cytosol [GO:0005829]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]
d1b26e1_d1l1fe1__1		Metazoa	Thermotogae	Chordata	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]
d1b26e2_d3tozh1__1			Thermotogae	Firmicutes	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1b26f1_d5k50g___1			Thermotogae		glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]	cellular amino acid metabolic process [GO:0006520]				glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]
d1b26f2_d3t4ea1__1			Thermotogae	Proteobacteria	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; NADP binding [GO:0050661]; quinate 3-dehydrogenase (NAD+) activity [GO:0030266]; quinate 3-dehydrogenase (NADP+) activity [GO:0052733]; shikimate 3-dehydrogenase (NAD+) activity [GO:0052734]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	NADP binding [GO:0050661]; quinate 3-dehydrogenase (NAD+) activity [GO:0030266]; quinate 3-dehydrogenase (NADP+) activity [GO:0052733]; shikimate 3-dehydrogenase (NAD+) activity [GO:0052734]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1b27a__d4haac___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1b2kb__d1l47a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1b2ma__d1aqzb___1	Fungi	Fungi	Ascomycota	Ascomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]; negative regulation of translation [GO:0017148]		negative regulation of translation [GO:0017148]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1b2ra1_d1ep3b1__1			Cyanobacteria	Firmicutes	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; 'de novo' UMP biosynthetic process [GO:0044205]	oxidation-reduction process [GO:0055114]	'de novo' UMP biosynthetic process [GO:0044205]	phycobilisome [GO:0030089]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]
d1b2ra1_d2vnia1__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1b2ra2_d3qfrb3__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	phycobilisome [GO:0030089]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1b2sd__d1b2ud___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1b2ua__d3hoha___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1b2va__d4y1qi___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1b2wh1_d5iwla1__1		Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; thrombospondin receptor activity [GO:0070053]; cell migration [GO:0016477]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; neutrophil degranulation [GO:0043312]; opsonization [GO:0008228]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of inflammatory response [GO:0050729]; positive regulation of phagocytosis [GO:0050766]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell activation [GO:0050870]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-10 production [GO:0032653]; regulation of interleukin-12 production [GO:0032655]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]; response to bacterium [GO:0009617]		cell migration [GO:0016477]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; neutrophil degranulation [GO:0043312]; opsonization [GO:0008228]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of inflammatory response [GO:0050729]; positive regulation of phagocytosis [GO:0050766]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell activation [GO:0050870]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-10 production [GO:0032653]; regulation of interleukin-12 production [GO:0032655]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]; response to bacterium [GO:0009617]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; thrombospondin receptor activity [GO:0070053]
d1b2wh2_d1f90h1__1												
d1b2wl1_d2bx5f___1		Metazoa		Chordata								
d1b2wl1_d3gb7b2__1				Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1b2wl2_d5xhga1__1												
d1b2za__d3d4aa___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1b2zb__d1brha___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1b2zc__d4haaa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1b30a__d1w91h2__1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d1b31a__d1bsia2__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	xylan catabolic process [GO:0045493]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular region [GO:0005576]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endo-1,4-beta-xylanase activity [GO:0031176]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1b31a__d1h5va___1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]
d1b33l__d3szka___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; photosynthesis [GO:0015979]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	photosynthesis [GO:0015979]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1b37c2_d1k0ja2__1	Viridiplantae		Streptophyta	Proteobacteria	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	benzoate catabolic process via hydroxylation [GO:0043640]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]		flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1b3ab__d2q8rh___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR1 chemokine receptor binding [GO:0031726]; CCR4 chemokine receptor binding [GO:0031729]; CCR5 chemokine receptor binding [GO:0031730]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; chemokine receptor antagonist activity [GO:0046817]; chemokine receptor binding [GO:0042379]; identical protein binding [GO:0042802]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase activator activity [GO:0016004]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein self-association [GO:0043621]; receptor signaling protein tyrosine kinase activator activity [GO:0030298]; activation of phospholipase D activity [GO:0031584]; calcium ion transport [GO:0006816]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell chemotaxis [GO:0002407]; eosinophil chemotaxis [GO:0048245]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of viral genome replication [GO:0045071]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cellular biosynthetic process [GO:0031328]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of innate immune response [GO:0045089]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphorylation [GO:0042327]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell apoptotic process [GO:0070234]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of T cell migration [GO:2000406]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of translational initiation [GO:0045948]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of viral genome replication [GO:0045070]; protein kinase B signaling [GO:0043491]; regulation of chronic inflammatory response [GO:0002676]; regulation of insulin secretion [GO:0050796]; regulation of neuron death [GO:1901214]; regulation of T cell activation [GO:0050863]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]	cell [GO:0005623]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	activation of phospholipase D activity [GO:0031584]; calcium ion transport [GO:0006816]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell chemotaxis [GO:0002407]; eosinophil chemotaxis [GO:0048245]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of viral genome replication [GO:0045071]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular biosynthetic process [GO:0031328]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of innate immune response [GO:0045089]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphorylation [GO:0042327]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell apoptotic process [GO:0070234]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of T cell migration [GO:2000406]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of translational initiation [GO:0045948]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of viral genome replication [GO:0045070]; protein kinase B signaling [GO:0043491]; regulation of chronic inflammatory response [GO:0002676]; regulation of insulin secretion [GO:0050796]; regulation of neuron death [GO:1901214]; regulation of T cell activation [GO:0050863]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]	cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell [GO:0005623]; extracellular space [GO:0005615]	CCR1 chemokine receptor binding [GO:0031726]; CCR4 chemokine receptor binding [GO:0031729]; CCR5 chemokine receptor binding [GO:0031730]; CCR chemokine receptor binding [GO:0048020]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; chemokine receptor antagonist activity [GO:0046817]; chemokine receptor binding [GO:0042379]; identical protein binding [GO:0042802]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase activator activity [GO:0016004]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein self-association [GO:0043621]; receptor signaling protein tyrosine kinase activator activity [GO:0030298]	CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]
d1b3ba1_d1nqtb1__1		Metazoa	Thermotogae	Chordata	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1b3ba2_d1nr7l2__1		Metazoa	Thermotogae	Chordata	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1b3ba2_d4xgid1__1			Thermotogae	Proteobacteria	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]			glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1b3bb2_d3toze1__1			Thermotogae	Firmicutes	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1b3bc2_d3etee1__1		Metazoa	Thermotogae	Chordata	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1b3bc2_d3r3jc1__1			Thermotogae	Apicomplexa	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	apicoplast [GO:0020011]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]; cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]		apicoplast [GO:0020011]; cytosol [GO:0005829]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]
d1b3be1_d3g49c___1		Metazoa	Thermotogae	Chordata	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; lung development [GO:0030324]; steroid metabolic process [GO:0008202]	cellular amino acid metabolic process [GO:0006520]	lung development [GO:0030324]; steroid metabolic process [GO:0008202]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]
d1b3be2_d1euze2__1			Thermotogae	Euryarchaeota	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]			glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d1b3be2_d1luac2__1			Thermotogae	Proteobacteria	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	cellular amino acid metabolic process [GO:0006520]	formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]		cytoplasm [GO:0005737]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]
d1b3bf2_d1nr1d2__1		Metazoa	Thermotogae	Chordata	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]
d1b3db__d3fora___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1b3fa__d2f34a___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	protein transport [GO:0015031]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	peptide transmembrane transporter activity [GO:1904680]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d1b3la__d4ykka___1		Metazoa	Proteobacteria	Ctenophora (ctenophores)	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ionotropic glutamate receptor activity [GO:0004970]	protein transport [GO:0015031]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	peptide transmembrane transporter activity [GO:1904680]	ionotropic glutamate receptor activity [GO:0004970]
d1b3na1_d5f0va2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; acetoacetic acid catabolic process [GO:0043442]; fatty acid beta-oxidation [GO:0006635]; protein homotetramerization [GO:0051289]	fatty acid biosynthetic process [GO:0006633]	acetoacetic acid catabolic process [GO:0043442]; fatty acid beta-oxidation [GO:0006635]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	acetyl-CoA C-acetyltransferase activity [GO:0003985]; acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d1b3na2_d4ubwb1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	fatty acid biosynthetic process [GO:0006633]	cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d1b3ra1_d4onea___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]		adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]
d1b3sa__d2f4ya___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1b3sf__d1b2se___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1b3va__d3mv123__1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	endo-1,4-beta-xylanase activity [GO:0031176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1b3va__d3zjka___1	Fungi		Ascomycota	Deinococcus-Thermus	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1b3wa__d4yn5a___1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]	endo-1,4-beta-xylanase activity [GO:0031176]	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]
d1b3xa__d2gdvb2__1	Fungi		Ascomycota	Actinobacteria	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	sucrose phosphorylase activity [GO:0009018]; cellular carbohydrate metabolic process [GO:0044262]	xylan catabolic process [GO:0045493]	cellular carbohydrate metabolic process [GO:0044262]	extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	sucrose phosphorylase activity [GO:0009018]
d1b3ya__d1mfva2__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	endo-1,4-beta-xylanase activity [GO:0031176]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d1b3za__d1jz1p5__1	Fungi		Ascomycota		extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	
d1b40a__d4lata___1			Proteobacteria	Firmicutes	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	plasma membrane [GO:0005886]; phosphate ion binding [GO:0042301]; phosphate ion transport [GO:0006817]	protein transport [GO:0015031]	phosphate ion transport [GO:0006817]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	plasma membrane [GO:0005886]	peptide transmembrane transporter activity [GO:1904680]	phosphate ion binding [GO:0042301]
d1b43b2_d5h4hb___1			Euryarchaeota	Euryarchaeota	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]				5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]
d1b44g__d2aq1h1__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]	extracellular region [GO:0005576]	T cell receptor complex [GO:0042101]	toxin activity [GO:0090729]	
d1b46a__d4la9b___1			Proteobacteria	Firmicutes	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	protein transport [GO:0015031]	nitrogen compound transport [GO:0071705]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	peptide transmembrane transporter activity [GO:1904680]	ligand-gated ion channel activity [GO:0015276]
d1b47b3_d2ysxa1__1	Metazoa	Metazoa	Chordata	Chordata	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; SH3 domain binding [GO:0017124]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; immunoglobulin mediated immune response [GO:0016064]; inositol phosphate metabolic process [GO:0043647]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of bone resorption [GO:0045779]; negative regulation of immune response [GO:0050777]; negative regulation of interleukin-6 biosynthetic process [GO:0045409]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of neutrophil differentiation [GO:0045659]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of signal transduction [GO:0009968]; phosphate-containing compound metabolic process [GO:0006796]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of erythrocyte differentiation [GO:0045648]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]	cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; immunoglobulin mediated immune response [GO:0016064]; inositol phosphate metabolic process [GO:0043647]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of bone resorption [GO:0045779]; negative regulation of immune response [GO:0050777]; negative regulation of interleukin-6 biosynthetic process [GO:0045409]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of neutrophil differentiation [GO:0045659]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of signal transduction [GO:0009968]; phosphate-containing compound metabolic process [GO:0006796]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of erythrocyte differentiation [GO:0045648]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; SH3 domain binding [GO:0017124]
d1b47c1_d1djib1__1	Metazoa	Metazoa	Chordata	Chordata	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]
d1b48a2_d2wb9b1__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]		drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1b48b1_d3vk9b2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]		drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d1b4aa2_d1f9nc2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1b4aa2_d3buea___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1b4ac2_d2zfza___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1b4ae1_d1f9nd1__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1b4af2_d2zfze___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1b4bb__d1xxbb___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]
d1b4bb__d2zfzc___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1b4cb__d2y5ia___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	calcium ion binding [GO:0005509]	astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]
d1b4fe__d3h8mb1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; receptor complex [GO:0043235]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; nervous system development [GO:0007399]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; brain development [GO:0007420]; branching morphogenesis of a nerve [GO:0048755]; ephrin receptor signaling pathway [GO:0048013]; negative chemotaxis [GO:0050919]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of synapse assembly [GO:0051964]; nephric duct morphogenesis [GO:0072178]; phosphorylation [GO:0016310]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell-cell adhesion [GO:0022407]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of postsynapse organization [GO:0099175]; regulation of protein autophosphorylation [GO:0031952]; retinal ganglion cell axon guidance [GO:0031290]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	angiogenesis [GO:0001525]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; nervous system development [GO:0007399]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]	apoptotic process [GO:0006915]; axon guidance [GO:0007411]; brain development [GO:0007420]; branching morphogenesis of a nerve [GO:0048755]; ephrin receptor signaling pathway [GO:0048013]; negative chemotaxis [GO:0050919]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of synapse assembly [GO:0051964]; nephric duct morphogenesis [GO:0072178]; phosphorylation [GO:0016310]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell-cell adhesion [GO:0022407]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of postsynapse organization [GO:0099175]; regulation of protein autophosphorylation [GO:0031952]; retinal ganglion cell axon guidance [GO:0031290]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; receptor complex [GO:0043235]	dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; protein tyrosine kinase activity [GO:0004713]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1b4fg__d3seib2__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; receptor complex [GO:0043235]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; nervous system development [GO:0007399]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	cytoplasm [GO:0005737]; membrane [GO:0016020]; identical protein binding [GO:0042802]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; nervous system development [GO:0007399]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]	signal transduction [GO:0007165]	axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; receptor complex [GO:0043235]	cytoplasm [GO:0005737]; membrane [GO:0016020]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	identical protein binding [GO:0042802]
d1b4jh1_d5gs1f1__1												
d1b4jh2_d4z5rl2__1		Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]		adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]		collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]
d1b4jl2_d4xwgl2__1		Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; high-density lipoprotein particle [GO:0034364]; apolipoprotein A-I binding [GO:0034186]; phosphatidylcholine-sterol O-acyltransferase activity [GO:0004607]; cholesterol esterification [GO:0034435]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; high-density lipoprotein particle remodeling [GO:0034375]; lipoprotein biosynthetic process [GO:0042158]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylcholine metabolic process [GO:0046470]; phospholipid metabolic process [GO:0006644]; regulation of high-density lipoprotein particle assembly [GO:0090107]; reverse cholesterol transport [GO:0043691]; very-low-density lipoprotein particle remodeling [GO:0034372]		cholesterol esterification [GO:0034435]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; high-density lipoprotein particle remodeling [GO:0034375]; lipoprotein biosynthetic process [GO:0042158]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylcholine metabolic process [GO:0046470]; phospholipid metabolic process [GO:0006644]; regulation of high-density lipoprotein particle assembly [GO:0090107]; reverse cholesterol transport [GO:0043691]; very-low-density lipoprotein particle remodeling [GO:0034372]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; high-density lipoprotein particle [GO:0034364]		apolipoprotein A-I binding [GO:0034186]; phosphatidylcholine-sterol O-acyltransferase activity [GO:0004607]
d1b4jl2_d5wkga2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1b4la__d1qupb1__1	Fungi	Fungi	Ascomycota	Ascomycota	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase copper chaperone activity [GO:0016532]; metal ion transport [GO:0030001]; protein maturation by copper ion transfer [GO:0015680]; removal of superoxide radicals [GO:0019430]	age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	metal ion transport [GO:0030001]; protein maturation by copper ion transfer [GO:0015680]; removal of superoxide radicals [GO:0019430]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]	copper ion binding [GO:0005507]; superoxide dismutase copper chaperone activity [GO:0016532]
d1b4ma__d1mfhc___1	Metazoa		Chordata		cytosol [GO:0005829]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol metabolic process [GO:0042572]		retinol metabolic process [GO:0042572]		cytosol [GO:0005829]		retinal binding [GO:0016918]; retinol binding [GO:0019841]	
d1b4na2_d1aora2__1			Euryarchaeota	Euryarchaeota	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor [GO:0016625]	4 iron, 4 sulfur cluster binding [GO:0051539]; aldehyde ferredoxin oxidoreductase activity [GO:0033726]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor [GO:0016625]	4 iron, 4 sulfur cluster binding [GO:0051539]; aldehyde ferredoxin oxidoreductase activity [GO:0033726]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1b4pa1_d3ik7c2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; glutathione metabolic process [GO:0006749]; response to catechin [GO:1902168]; response to genistein [GO:0033595]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; glutathione metabolic process [GO:0006749]; response to catechin [GO:1902168]; response to genistein [GO:0033595]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1b4pa2_d2mbta1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; glutathione metabolic process [GO:0006749]; response to catechin [GO:1902168]; response to genistein [GO:0033595]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	aging [GO:0007568]; glutathione metabolic process [GO:0006749]; response to catechin [GO:1902168]; response to genistein [GO:0033595]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cell [GO:0005623]; periplasmic space [GO:0042597]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	protein disulfide oxidoreductase activity [GO:0015035]
d1b4qa__d5evoa1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; glutathione oxidoreductase activity [GO:0097573]; protein N-terminus binding [GO:0047485]; cell redox homeostasis [GO:0045454]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of membrane potential [GO:0045838]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein deglutathionylation [GO:0080058]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]	cell redox homeostasis [GO:0045454]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of membrane potential [GO:0045838]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein deglutathionylation [GO:0080058]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]		electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; glutathione oxidoreductase activity [GO:0097573]; protein N-terminus binding [GO:0047485]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]
d1b4ra__d1l0qa1__1	Metazoa		Chordata	Euryarchaeota	basolateral plasma membrane [GO:0016323]; calcium channel complex [GO:0034704]; cation channel complex [GO:0034703]; cell [GO:0005623]; cell surface [GO:0009986]; ciliary membrane [GO:0060170]; cilium [GO:0005929]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; lateral plasma membrane [GO:0016328]; motile cilium [GO:0031514]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; polycystin complex [GO:0002133]; calcium channel activity [GO:0005262]; carbohydrate binding [GO:0030246]; ion channel binding [GO:0044325]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Wnt-activated receptor activity [GO:0042813]; anatomical structure morphogenesis [GO:0009653]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion transmembrane transport [GO:0070588]; calcium-independent cell-matrix adhesion [GO:0007161]; cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; cell cycle arrest [GO:0007050]; cell-cell signaling by wnt [GO:0198738]; cell-matrix adhesion [GO:0007160]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; digestive tract development [GO:0048565]; embryonic placenta development [GO:0001892]; establishment of cell polarity [GO:0030010]; genitalia development [GO:0048806]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; liver development [GO:0001889]; lung epithelium development [GO:0060428]; lymph vessel morphogenesis [GO:0036303]; mesonephric duct development [GO:0072177]; mesonephric tubule development [GO:0072164]; metanephric ascending thin limb development [GO:0072218]; metanephric collecting duct development [GO:0072205]; metanephric distal tubule morphogenesis [GO:0072287]; metanephric proximal tubule development [GO:0072237]; neural tube development [GO:0021915]; peptidyl-serine phosphorylation [GO:0018105]; placenta blood vessel development [GO:0060674]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein export from nucleus [GO:0006611]; protein heterotetramerization [GO:0051290]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell adhesion [GO:0030155]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic spindle organization [GO:0060236]; regulation of proteasomal protein catabolic process [GO:0061136]; response to fluid shear stress [GO:0034405]; skin development [GO:0043588]; spinal cord development [GO:0021510]	integral component of membrane [GO:0016021]	anatomical structure morphogenesis [GO:0009653]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium-independent cell-matrix adhesion [GO:0007161]; calcium ion transmembrane transport [GO:0070588]; cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; cell-cell signaling by wnt [GO:0198738]; cell cycle arrest [GO:0007050]; cell-matrix adhesion [GO:0007160]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; digestive tract development [GO:0048565]; embryonic placenta development [GO:0001892]; establishment of cell polarity [GO:0030010]; genitalia development [GO:0048806]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; liver development [GO:0001889]; lung epithelium development [GO:0060428]; lymph vessel morphogenesis [GO:0036303]; mesonephric duct development [GO:0072177]; mesonephric tubule development [GO:0072164]; metanephric ascending thin limb development [GO:0072218]; metanephric collecting duct development [GO:0072205]; metanephric distal tubule morphogenesis [GO:0072287]; metanephric proximal tubule development [GO:0072237]; neural tube development [GO:0021915]; peptidyl-serine phosphorylation [GO:0018105]; placenta blood vessel development [GO:0060674]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein export from nucleus [GO:0006611]; protein heterotetramerization [GO:0051290]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell adhesion [GO:0030155]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic spindle organization [GO:0060236]; regulation of proteasomal protein catabolic process [GO:0061136]; response to fluid shear stress [GO:0034405]; skin development [GO:0043588]; spinal cord development [GO:0021510]		basolateral plasma membrane [GO:0016323]; calcium channel complex [GO:0034704]; cation channel complex [GO:0034703]; cell [GO:0005623]; cell surface [GO:0009986]; ciliary membrane [GO:0060170]; cilium [GO:0005929]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; lateral plasma membrane [GO:0016328]; motile cilium [GO:0031514]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; polycystin complex [GO:0002133]	integral component of membrane [GO:0016021]	calcium channel activity [GO:0005262]; carbohydrate binding [GO:0030246]; ion channel binding [GO:0044325]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Wnt-activated receptor activity [GO:0042813]	
d1b4xa__d2bi2a___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	L-serine biosynthetic process [GO:0006564]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]
d1b51a__d4gxab___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; cysteine biosynthetic process [GO:0019344]	protein transport [GO:0015031]	cysteine biosynthetic process [GO:0019344]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]	peptide transmembrane transporter activity [GO:1904680]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1b56a__d4orxb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]; epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d1b58a__d4ykib___1		Metazoa	Proteobacteria	Ctenophora (ctenophores)	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ionotropic glutamate receptor activity [GO:0004970]	protein transport [GO:0015031]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	peptide transmembrane transporter activity [GO:1904680]	ionotropic glutamate receptor activity [GO:0004970]
d1b5aa__d1eueb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; response to cadmium ion [GO:0046686]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	response to cadmium ion [GO:0046686]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]	electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1b5f.1_d3ogqb___1	Viridiplantae		Streptophyta		cell wall [GO:0005618]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; organelle membrane [GO:0031090]; protein storage vacuole [GO:0000326]; aspartic-type endopeptidase activity [GO:0004190]; lipid metabolic process [GO:0006629]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	lipid metabolic process [GO:0006629]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	cell wall [GO:0005618]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; organelle membrane [GO:0031090]; protein storage vacuole [GO:0000326]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d1b5pb__d1spaa___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	biosynthetic process [GO:0009058]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1b5qa2_d1daob2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d1b5qb2_d2xfua2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1b5qc2_d1ng4b2__1	Viridiplantae		Streptophyta	Firmicutes	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]; cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	cytoplasm [GO:0005737]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]	FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]
d1b5sb__d1xmcb2__1		Metazoa	Firmicutes	Chordata	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-octanoyltransferase activity [GO:0008458]; carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; response to drug [GO:0042493]	glycolytic process [GO:0006096]	carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; response to drug [GO:0042493]		intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]	carnitine O-octanoyltransferase activity [GO:0008458]
d1b5sb__d3u9fm___1			Firmicutes	Proteobacteria	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	glycolytic process [GO:0006096]	response to antibiotic [GO:0046677]			dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d1b5sc__d4ep9a1__1		Metazoa	Firmicutes	Chordata	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	glycolytic process [GO:0006096]	fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]	carnitine O-palmitoyltransferase activity [GO:0004095]
d1b5sd__d2ii3c___1		Metazoa	Firmicutes	Chordata	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	glycolytic process [GO:0006096]			cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1b5tb__d4jnza2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; FAD binding [GO:0071949]; methylenetetrahydrofolate reductase (NAD(P)H) activity [GO:0004489]; methionine biosynthetic process [GO:0009086]; protein homotetramerization [GO:0051289]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate interconversion [GO:0035999]	cytoplasmic side of plasma membrane [GO:0009898]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]; proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	methionine biosynthetic process [GO:0009086]; protein homotetramerization [GO:0051289]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate interconversion [GO:0035999]	proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	cytosol [GO:0005829]	cytoplasmic side of plasma membrane [GO:0009898]	FAD binding [GO:0071949]; methylenetetrahydrofolate reductase (NAD(P)H) activity [GO:0004489]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]
d1b5va__d180la___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1b5za__d1g1wa___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1b5zb__d1dyea___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1b5zb__d4lyta___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1b66b__d1xxjc2__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin biosynthetic process [GO:0006729]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	tetrahydrobiopterin biosynthetic process [GO:0006729]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	mitochondrion [GO:0005739]	peroxisome [GO:0005777]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	urate oxidase activity [GO:0004846]
d1b6ba__d5dwnd___1	Metazoa		Chordata	Proteobacteria	perinuclear region of cytoplasm [GO:0048471]; aralkylamine N-acetyltransferase activity [GO:0004059]; cellular response to cAMP [GO:0071320]; circadian rhythm [GO:0007623]; melatonin biosynthetic process [GO:0030187]; N-terminal protein amino acid acetylation [GO:0006474]	N-acetyltransferase activity [GO:0008080]	cellular response to cAMP [GO:0071320]; circadian rhythm [GO:0007623]; melatonin biosynthetic process [GO:0030187]; N-terminal protein amino acid acetylation [GO:0006474]		perinuclear region of cytoplasm [GO:0048471]		aralkylamine N-acetyltransferase activity [GO:0004059]	N-acetyltransferase activity [GO:0008080]
d1b6cf__d4nw6a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; ribosomal protein S6 kinase activity [GO:0004711]; cell cycle [GO:0007049]; central nervous system development [GO:0007417]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of translation in response to stress [GO:0043555]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; toll-like receptor signaling pathway [GO:0002224]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell cycle [GO:0007049]; central nervous system development [GO:0007417]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of translation in response to stress [GO:0043555]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; toll-like receptor signaling pathway [GO:0002224]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	ATP binding [GO:0005524]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; ribosomal protein S6 kinase activity [GO:0004711]
d1b6da1_d1wcbl2__1												
d1b6db1_d1c5dl1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1b6ra1_d1dv1b1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1b6ra1_d4mv4a3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytosol [GO:0005829]		5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1b6ra2_d5jcbf1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	cell [GO:0005623]; nucleotide binding [GO:0000166]; tubulin-tyrosine ligase activity [GO:0004835]; C-terminal protein-tyrosinylation [GO:0018166]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of axon extension [GO:0030516]; regulation of metaphase plate congression [GO:0090235]	'de novo' IMP biosynthetic process [GO:0006189]	C-terminal protein-tyrosinylation [GO:0018166]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of axon extension [GO:0030516]; regulation of metaphase plate congression [GO:0090235]	cytosol [GO:0005829]	cell [GO:0005623]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	nucleotide binding [GO:0000166]; tubulin-tyrosine ligase activity [GO:0004835]
d1b6sa1_d2w70a3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1b6sa2_d1cs0g3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1b6sc1_d2yw2b3__1			Proteobacteria	Aquificae	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytosol [GO:0005829]		5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d1b6sd1_d1kjib1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]	cytosol [GO:0005829]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d1b6sd2_d1cs0g4__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1b6tb__d3rhsa___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1b6ua2_d1olzb1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; signaling receptor activity [GO:0038023]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; chemorepellent activity [GO:0045499]; identical protein binding [GO:0042802]; semaphorin receptor binding [GO:0030215]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; cell adhesion [GO:0007155]; immune response [GO:0006955]; leukocyte aggregation [GO:0070486]; negative chemotaxis [GO:0050919]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; ossification involved in bone maturation [GO:0043931]; positive regulation of cell migration [GO:0030335]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of GTPase activity [GO:0043547]; positive regulation of inhibitory synapse assembly [GO:1905704]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell projection organization [GO:0031344]; regulation of cell shape [GO:0008360]; regulation of dendrite morphogenesis [GO:0048814]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220]	immune response [GO:0006955]; regulation of immune response [GO:0050776]	cell adhesion [GO:0007155]; immune response [GO:0006955]; leukocyte aggregation [GO:0070486]; negative chemotaxis [GO:0050919]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; ossification involved in bone maturation [GO:0043931]; positive regulation of cell migration [GO:0030335]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of GTPase activity [GO:0043547]; positive regulation of inhibitory synapse assembly [GO:1905704]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell projection organization [GO:0031344]; regulation of cell shape [GO:0008360]; regulation of dendrite morphogenesis [GO:0048814]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220]	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; signaling receptor activity [GO:0038023]	chemorepellent activity [GO:0045499]; identical protein binding [GO:0042802]; semaphorin receptor binding [GO:0030215]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]
d1b6za__d3p9fa1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin biosynthetic process [GO:0006729]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	tetrahydrobiopterin biosynthetic process [GO:0006729]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	mitochondrion [GO:0005739]	peroxisome [GO:0005777]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	urate oxidase activity [GO:0004846]
d1b6zb__d1ws3a1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin biosynthetic process [GO:0006729]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	tetrahydrobiopterin biosynthetic process [GO:0006729]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	mitochondrion [GO:0005739]	peroxisome [GO:0005777]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	urate oxidase activity [GO:0004846]
d1b70b2_d2iy5b2__1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	phenylalanyl-tRNA aminoacylation [GO:0006432]	phenylalanyl-tRNA aminoacylation [GO:0006432]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]
d1b73a1_d5elmc1__1			Aquificae	Proteobacteria	glutamate racemase activity [GO:0008881]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	aspartate racemase activity [GO:0047689]; glutamate racemase activity [GO:0008881]; identical protein binding [GO:0042802]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	nitrogen compound metabolic process [GO:0006807]			glutamate racemase activity [GO:0008881]	aspartate racemase activity [GO:0047689]; glutamate racemase activity [GO:0008881]; identical protein binding [GO:0042802]
d1b76a1_d4hwpa2__1			Deinococcus-Thermus	Proteobacteria	glycine-tRNA ligase complex [GO:0009345]; ATP binding [GO:0005524]; glycine binding [GO:0016594]; glycine-tRNA ligase activity [GO:0004820]; magnesium ion binding [GO:0000287]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; glycyl-tRNA aminoacylation [GO:0006426]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	glycyl-tRNA aminoacylation [GO:0006426]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	glycine-tRNA ligase complex [GO:0009345]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; glycine binding [GO:0016594]; glycine-tRNA ligase activity [GO:0004820]; magnesium ion binding [GO:0000287]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1b77a1_d3f1wa1__1		Fungi		Ascomycota	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]		chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]
d1b77a1_d4pnwa2__1					DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]		DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]					
d1b77b1_d3lx2a2__1				Euryarchaeota	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]		PCNA complex [GO:0043626]		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]
d1b7ba__d2v5hc___1			Firmicutes	Cyanobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]; arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; regulation of nitrogen utilization [GO:0006808]	arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	regulation of nitrogen utilization [GO:0006808]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d1b7bc__d3ek5f___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]; arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	cytosol [GO:0005829]; ATP binding [GO:0005524]; UMP kinase activity [GO:0033862]; 'de novo' CTP biosynthetic process [GO:0044210]; UDP biosynthetic process [GO:0006225]	arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	'de novo' CTP biosynthetic process [GO:0044210]; UDP biosynthetic process [GO:0006225]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]	ATP binding [GO:0005524]; UMP kinase activity [GO:0033862]
d1b7bd__d2j4jf___1			Firmicutes	Crenarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]; arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; UMP kinase activity [GO:0033862]; 'de novo' CTP biosynthetic process [GO:0044210]; UDP biosynthetic process [GO:0006225]	arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	'de novo' CTP biosynthetic process [GO:0044210]; UDP biosynthetic process [GO:0006225]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]	ATP binding [GO:0005524]; UMP kinase activity [GO:0033862]
d1b7fa1_d1u1na1__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; poly(U) RNA binding [GO:0008266]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; alternative mRNA splicing, via spliceosome [GO:0000380]; dosage compensation [GO:0007549]; epithelium regeneration [GO:1990399]; female sex determination [GO:0030237]; imaginal disc growth [GO:0007446]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of translation [GO:0017148]; oocyte differentiation [GO:0009994]; oogenesis [GO:0048477]; positive regulation of RNA splicing [GO:0033120]; positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; reciprocal meiotic recombination [GO:0007131]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of stem cell division [GO:2000035]; sex determination [GO:0007530]; sex determination, primary response to X:A ratio [GO:0007541]; sex differentiation [GO:0007548]; somatic sex determination [GO:0018993]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	alternative mRNA splicing, via spliceosome [GO:0000380]; dosage compensation [GO:0007549]; epithelium regeneration [GO:1990399]; female sex determination [GO:0030237]; imaginal disc growth [GO:0007446]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of translation [GO:0017148]; oocyte differentiation [GO:0009994]; oogenesis [GO:0048477]; positive regulation of RNA splicing [GO:0033120]; positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; reciprocal meiotic recombination [GO:0007131]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of stem cell division [GO:2000035]; sex determination [GO:0007530]; sex determination, primary response to X:A ratio [GO:0007541]; sex differentiation [GO:0007548]; somatic sex determination [GO:0018993]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; poly(U) RNA binding [GO:0008266]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]
d1b7fa1_d4egla1__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; poly(U) RNA binding [GO:0008266]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; alternative mRNA splicing, via spliceosome [GO:0000380]; dosage compensation [GO:0007549]; epithelium regeneration [GO:1990399]; female sex determination [GO:0030237]; imaginal disc growth [GO:0007446]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of translation [GO:0017148]; oocyte differentiation [GO:0009994]; oogenesis [GO:0048477]; positive regulation of RNA splicing [GO:0033120]; positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; reciprocal meiotic recombination [GO:0007131]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of stem cell division [GO:2000035]; sex determination [GO:0007530]; sex determination, primary response to X:A ratio [GO:0007541]; sex differentiation [GO:0007548]; somatic sex determination [GO:0018993]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	alternative mRNA splicing, via spliceosome [GO:0000380]; dosage compensation [GO:0007549]; epithelium regeneration [GO:1990399]; female sex determination [GO:0030237]; imaginal disc growth [GO:0007446]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of translation [GO:0017148]; oocyte differentiation [GO:0009994]; oogenesis [GO:0048477]; positive regulation of RNA splicing [GO:0033120]; positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; reciprocal meiotic recombination [GO:0007131]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of stem cell division [GO:2000035]; sex determination [GO:0007530]; sex determination, primary response to X:A ratio [GO:0007541]; sex differentiation [GO:0007548]; somatic sex determination [GO:0018993]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]	mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; poly(U) RNA binding [GO:0008266]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d1b7fa2_d3l3cb___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; poly(U) RNA binding [GO:0008266]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; alternative mRNA splicing, via spliceosome [GO:0000380]; dosage compensation [GO:0007549]; epithelium regeneration [GO:1990399]; female sex determination [GO:0030237]; imaginal disc growth [GO:0007446]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of translation [GO:0017148]; oocyte differentiation [GO:0009994]; oogenesis [GO:0048477]; positive regulation of RNA splicing [GO:0033120]; positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; reciprocal meiotic recombination [GO:0007131]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of stem cell division [GO:2000035]; sex determination [GO:0007530]; sex determination, primary response to X:A ratio [GO:0007541]; sex differentiation [GO:0007548]; somatic sex determination [GO:0018993]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	alternative mRNA splicing, via spliceosome [GO:0000380]; dosage compensation [GO:0007549]; epithelium regeneration [GO:1990399]; female sex determination [GO:0030237]; imaginal disc growth [GO:0007446]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of translation [GO:0017148]; oocyte differentiation [GO:0009994]; oogenesis [GO:0048477]; positive regulation of RNA splicing [GO:0033120]; positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; reciprocal meiotic recombination [GO:0007131]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of stem cell division [GO:2000035]; sex determination [GO:0007530]; sex determination, primary response to X:A ratio [GO:0007541]; sex differentiation [GO:0007548]; somatic sex determination [GO:0018993]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; poly(U) RNA binding [GO:0008266]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]
d1b7fb1_d3p6yk___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; poly(U) RNA binding [GO:0008266]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; alternative mRNA splicing, via spliceosome [GO:0000380]; dosage compensation [GO:0007549]; epithelium regeneration [GO:1990399]; female sex determination [GO:0030237]; imaginal disc growth [GO:0007446]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of translation [GO:0017148]; oocyte differentiation [GO:0009994]; oogenesis [GO:0048477]; positive regulation of RNA splicing [GO:0033120]; positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; reciprocal meiotic recombination [GO:0007131]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of stem cell division [GO:2000035]; sex determination [GO:0007530]; sex determination, primary response to X:A ratio [GO:0007541]; sex differentiation [GO:0007548]; somatic sex determination [GO:0018993]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	alternative mRNA splicing, via spliceosome [GO:0000380]; dosage compensation [GO:0007549]; epithelium regeneration [GO:1990399]; female sex determination [GO:0030237]; imaginal disc growth [GO:0007446]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of translation [GO:0017148]; oocyte differentiation [GO:0009994]; oogenesis [GO:0048477]; positive regulation of RNA splicing [GO:0033120]; positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; reciprocal meiotic recombination [GO:0007131]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of stem cell division [GO:2000035]; sex determination [GO:0007530]; sex determination, primary response to X:A ratio [GO:0007541]; sex differentiation [GO:0007548]; somatic sex determination [GO:0018993]	messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; poly(U) RNA binding [GO:0008266]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]
d1b7gq2_d2pkrc2__1		Viridiplantae	Crenarchaeota	Streptophyta	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1b7ha__d3vvdb1__1			Proteobacteria	Deinococcus-Thermus	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	protein transport [GO:0015031]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	membrane [GO:0016020]	peptide transmembrane transporter activity [GO:1904680]	ligand-gated ion channel activity [GO:0015276]
d1b7na__d4h9aa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1b7oa__d1l40a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1b7pa__d1lsea___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1b7qa__d4g9sa1__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; periplasmic space [GO:0042597]; lysozyme inhibitor activity [GO:0060241]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; periplasmic space [GO:0042597]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme inhibitor activity [GO:0060241]
d1b7ra__d1sswa___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1b7sa__d1swza___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1b7tz__d1yrub___1	Metazoa	Metazoa	Mollusca	Chordata	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1b7za1_d1ryxa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	extracellular space [GO:0005615]; specific granule [GO:0042581]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]
d1b7za1_d4f39a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	extracellular space [GO:0005615]; specific granule [GO:0042581]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1b7za2_d1b3lc___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	protein transport [GO:0015031]	extracellular space [GO:0005615]; specific granule [GO:0042581]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]	peptide transmembrane transporter activity [GO:1904680]
d1b7za2_d1jw1a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	extracellular space [GO:0005615]; specific granule [GO:0042581]	extracellular space [GO:0005615]; specific granule [GO:0042581]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d1b85b__d5syya2__1	Fungi		Basidiomycota	Proteobacteria	diarylpropane peroxidase activity [GO:0016690]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]			diarylpropane peroxidase activity [GO:0016690]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1b86d__d5uvka___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1b8aa2_d2zgwa2__1			Euryarchaeota	Euryarchaeota	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	aspartyl-tRNA aminoacylation [GO:0006422]	cellular protein modification process [GO:0006464]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]		aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d1b8ab1_d4pofc1__1			Euryarchaeota	Euryarchaeota	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; cell division [GO:0051301]; DNA replication initiation [GO:0006270]; intein-mediated protein splicing [GO:0016539]	aspartyl-tRNA aminoacylation [GO:0006422]	cell division [GO:0051301]; DNA replication initiation [GO:0006270]; intein-mediated protein splicing [GO:0016539]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]		aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d1b8ha2_d1ud9b2__1				Crenarchaeota	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d1b8hb1_d2pola1__1				Proteobacteria	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1b8hb2_d3d1gb1__1				Proteobacteria	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1b8hc2_d3d1ga3__1				Proteobacteria	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1b8hc2_d3wgwb1__1		Metazoa		Chordata	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]		centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d1b8oa__d4eced___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	nucleoside metabolic process [GO:0009116]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	purine-nucleoside phosphorylase activity [GO:0004731]	drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]
d1b8sa2_d1el5b2__1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	cholesterol metabolic process [GO:0008203]	tetrahydrofolate metabolic process [GO:0046653]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]	sarcosine oxidase activity [GO:0008115]
d1b8xa1_d3ik9f2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione transferase activity [GO:0004364]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1b8ya__d3fgda___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1b90a2_d3muz13__1			Firmicutes	Proteobacteria	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1b90a2_d5td4a1__1		Metazoa	Firmicutes	Chordata	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	polysaccharide catabolic process [GO:0000272]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1b93a__d1jdbb2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1b93b__d1p4ra1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	methylglyoxal synthase activity [GO:0008929]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1b93b__d1s8ac___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	methylglyoxal synthase activity [GO:0008929]
d1b95a__d1qpsa___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]
d1b95a__d4rveb___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]
d1b96a__d1b97b___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]
d1b96a__d1wdja___1			Proteobacteria	Deinococcus-Thermus	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]		DNA restriction-modification system [GO:0009307]				DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]	
d1b96b__d1ckqa___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]
d1b99a__d5u2id1__1				Heterolobosea	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d1b99c__d3prvc___1					cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d1b99d__d4dz6a1__1				Spirochaetes	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1b99e__d5kk8a1__1		Metazoa		Platyhelminthes	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	nucleoside diphosphate kinase activity [GO:0004550]
d1b9ba__d2yc8k___1			Thermotogae		cytosol [GO:0005829]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; triose-phosphate isomerase activity [GO:0004807]; fatty acid biosynthetic process [GO:0006633]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; positive regulation of oxidative phosphorylation [GO:1903862]		fatty acid biosynthetic process [GO:0006633]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; positive regulation of oxidative phosphorylation [GO:1903862]		cytosol [GO:0005829]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; triose-phosphate isomerase activity [GO:0004807]	
d1b9bb__d3taoa___1			Thermotogae	Actinobacteria	cytosol [GO:0005829]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; triose-phosphate isomerase activity [GO:0004807]; fatty acid biosynthetic process [GO:0006633]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; positive regulation of oxidative phosphorylation [GO:1903862]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	fatty acid biosynthetic process [GO:0006633]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; positive regulation of oxidative phosphorylation [GO:1903862]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1b9ia__d1ijia___1			Actinobacteria	Proteobacteria	lyase activity [GO:0016829]; transferase activity [GO:0016740]; antibiotic biosynthetic process [GO:0017000]	cytosol [GO:0005829]; histidinol-phosphate transaminase activity [GO:0004400]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	antibiotic biosynthetic process [GO:0017000]	histidine biosynthetic process [GO:0000105]		cytosol [GO:0005829]	lyase activity [GO:0016829]; transferase activity [GO:0016740]	histidinol-phosphate transaminase activity [GO:0004400]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]
d1b9ja__d3c32b___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	protein transport [GO:0015031]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	peptide transmembrane transporter activity [GO:1904680]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d1b9ka1_d1om9b___1	Metazoa	Metazoa	Chordata	Chordata	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]
d1b9la__d5ll1b2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]; folic acid-containing compound metabolic process [GO:0006760]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid-containing compound metabolic process [GO:0006760]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytosol [GO:0005829]	peroxisome [GO:0005777]	dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]	urate oxidase activity [GO:0004846]
d1b9lc__d3pkka2__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]; folic acid-containing compound metabolic process [GO:0006760]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid-containing compound metabolic process [GO:0006760]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytosol [GO:0005829]	peroxisome [GO:0005777]	dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]	urate oxidase activity [GO:0004846]
d1b9ld__d2yzbe1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]; folic acid-containing compound metabolic process [GO:0006760]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid-containing compound metabolic process [GO:0006760]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytosol [GO:0005829]		dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]	urate oxidase activity [GO:0004846]
d1b9le__d1r56a2__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]; folic acid-containing compound metabolic process [GO:0006760]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid-containing compound metabolic process [GO:0006760]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytosol [GO:0005829]	peroxisome [GO:0005777]	dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]	urate oxidase activity [GO:0004846]
d1b9le__d1sqlk___1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]; folic acid-containing compound metabolic process [GO:0006760]	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytosol [GO:0005829]	dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]	dihydroneopterin aldolase activity [GO:0004150]
d1b9lg__d1wuqa___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]; folic acid-containing compound metabolic process [GO:0006760]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1b9lh__d1gtpn___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]; folic acid-containing compound metabolic process [GO:0006760]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1b9oa__d1l18a___1	Metazoa		Chordata		extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]	host cell cytoplasm [GO:0030430]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]	lysozyme activity [GO:0003796]
d1b9ta__d2hu0f___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1b9va__d3ti4a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1b9va__d5kv8a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d1b9za1_d2fhfa3__1			Firmicutes	Proteobacteria	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		plasma membrane [GO:0005886]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]
d1ba0a1_d3ldla1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1ba8.1_d2zu2a___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1baba__d3w4uc___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1babc__d1v4uc___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1babc__d2uunx___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1babd__d1y4qa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1bafh1_d2vira2__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d1bafl2_d1sy6l1__1		Metazoa		Chordata		alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]
d1baga2_d4pmua___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d1baia__d5p0la___1		Fungi		Ascomycota	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; reverse transcription [GO:0001171]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; reverse transcription [GO:0001171]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]		viral nucleocapsid [GO:0019013]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1baja__d2eiaa1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral nucleocapsid [GO:0019013]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral budding via host ESCRT complex [GO:0039702]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral budding via host ESCRT complex [GO:0039702]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	viral nucleocapsid [GO:0019013]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d1bana__d1rgha___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1baoc__d1bngb___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1bapa__d4ry9a___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; ATPase-coupled monosaccharide transmembrane transporter activity [GO:0015407]; monosaccharide binding [GO:0048029]; L-arabinose transmembrane transport [GO:0042882]		L-arabinose transmembrane transport [GO:0042882]		outer membrane-bounded periplasmic space [GO:0030288]		ATPase-coupled monosaccharide transmembrane transporter activity [GO:0015407]; monosaccharide binding [GO:0048029]	
d1basa__d3jute___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1bavb__d2iq6a___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	proteolysis [GO:0006508]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]
d1bawa__d2xwzd1__1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	thylakoid membrane [GO:0042651]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1bawc__d3heip1__1		Metazoa	Cyanobacteria	Chordata	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]		activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	thylakoid membrane [GO:0042651]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]
d1baxa__d2jmga___1					host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral budding via host ESCRT complex [GO:0039702]	virion [GO:0019012]; structural molecule activity [GO:0005198]; viral process [GO:0016032]	viral budding via host ESCRT complex [GO:0039702]	viral process [GO:0016032]	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]	virion [GO:0019012]	nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	structural molecule activity [GO:0005198]
d1bb3a__d228la___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1bb3b__d4i7qa1__1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1bb4a__d167lb___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1bbba__d1mboa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1bbbd__d2g0sa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1bbdl2_d4m7kl1__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]	
d1bbha__d3hnig___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1bbhb__d3m79c___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1bbja1_d3sdxh2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1bbja2_d3t2nm1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]; basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]
d1bbjb1_d4m5ym1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1bbjh1_d4hk0b2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1bbjh2_d4jrec1__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; inorganic anion exchanger activity [GO:0005452]; nitrate transmembrane transporter activity [GO:0015112]; nitrite efflux transmembrane transporter activity [GO:0015514]; nitrate assimilation [GO:0042128]; nitrate transport [GO:0015706]; nitrite transport [GO:0015707]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	nitrate assimilation [GO:0042128]; nitrate transport [GO:0015706]; nitrite transport [GO:0015707]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	inorganic anion exchanger activity [GO:0005452]; nitrate transmembrane transporter activity [GO:0015112]; nitrite efflux transmembrane transporter activity [GO:0015514]
d1bbjh2_d5hbtc2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	acetylcholine-gated channel complex [GO:0005892]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic specialization membrane [GO:0099060]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; acetylcholine binding [GO:0042166]; acetylcholine receptor activity [GO:0015464]; acetylcholine-gated cation-selective channel activity [GO:0022848]; ion channel activity [GO:0005216]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; muscle cell cellular homeostasis [GO:0046716]; musculoskeletal movement [GO:0050881]; nervous system process [GO:0050877]; neuromuscular junction development [GO:0007528]; neuromuscular process [GO:0050905]; neuromuscular synaptic transmission [GO:0007274]; neuron cellular homeostasis [GO:0070050]; neuronal action potential [GO:0019228]; regulation of membrane potential [GO:0042391]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; skeletal muscle contraction [GO:0003009]; skeletal muscle tissue growth [GO:0048630]; synaptic transmission, cholinergic [GO:0007271]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; muscle cell cellular homeostasis [GO:0046716]; musculoskeletal movement [GO:0050881]; nervous system process [GO:0050877]; neuromuscular junction development [GO:0007528]; neuromuscular process [GO:0050905]; neuromuscular synaptic transmission [GO:0007274]; neuronal action potential [GO:0019228]; neuron cellular homeostasis [GO:0070050]; regulation of membrane potential [GO:0042391]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; skeletal muscle contraction [GO:0003009]; skeletal muscle tissue growth [GO:0048630]; synaptic transmission, cholinergic [GO:0007271]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	acetylcholine-gated channel complex [GO:0005892]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic specialization membrane [GO:0099060]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	acetylcholine binding [GO:0042166]; acetylcholine-gated cation-selective channel activity [GO:0022848]; acetylcholine receptor activity [GO:0015464]; ion channel activity [GO:0005216]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1bbr.1_d5t6ga1__1	Metazoa		Chordata		extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	extracellular space [GO:0005615]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]
d1bbr.3_d3zv9a1__1	Metazoa		Chordata		extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1bbua2_d1nj1a3__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	prolyl-tRNA aminoacylation [GO:0006433]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]
d1bbxc__d1ca6a___1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]	DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]
d1bc9a__d4d7ra1__1	Metazoa		Chordata	Proteobacteria	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; lipid binding [GO:0008289]; establishment of epithelial cell polarity [GO:0090162]; regulation of ARF protein signal transduction [GO:0032012]; regulation of cell adhesion [GO:0030155]; vesicle-mediated transport [GO:0016192]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; regulation of ARF protein signal transduction [GO:0032012]	establishment of epithelial cell polarity [GO:0090162]; regulation of ARF protein signal transduction [GO:0032012]; regulation of cell adhesion [GO:0030155]; vesicle-mediated transport [GO:0016192]	regulation of ARF protein signal transduction [GO:0032012]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]		ARF guanyl-nucleotide exchange factor activity [GO:0005086]; lipid binding [GO:0008289]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]
d1bcca1_d3h1hn2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1bccb2_d3cxhb2__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	
d1bcfa__d1fz5c___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1bcfh__d1fz7a___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1bcfj__d1afrc___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	chloroplast [GO:0009507]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d1bch11_d3c8jd___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cell adhesion [GO:0007155]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]
d1bcj21_d4zrvb1__1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; pattern recognition receptor activity [GO:0038187]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway [GO:0038094]; innate immune response [GO:0045087]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cytokine secretion [GO:0050715]; T cell differentiation involved in immune response [GO:0002292]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway [GO:0038094]; innate immune response [GO:0045087]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cytokine secretion [GO:0050715]; T cell differentiation involved in immune response [GO:0002292]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	integral component of membrane [GO:0016021]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; pattern recognition receptor activity [GO:0038187]
d1bcmb2_d1wsfd___1				Proteobacteria	host cell cytoplasm [GO:0030430]; DNA binding [GO:0003677]; double-stranded DNA endodeoxyribonuclease activity [GO:1990238]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; transposase activity [GO:0004803]; DNA integration [GO:0015074]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; latency-replication decision [GO:0098689]; transposition, DNA-mediated [GO:0006313]; viral DNA genome replication [GO:0039693]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA integration [GO:0015074]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; latency-replication decision [GO:0098689]; transposition, DNA-mediated [GO:0006313]; viral DNA genome replication [GO:0039693]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; double-stranded DNA endodeoxyribonuclease activity [GO:1990238]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; transposase activity [GO:0004803]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1bcna__d1ekua1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]; activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular respiration [GO:1901857]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of iron ion import across plasma membrane [GO:1904440]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vitamin D biosynthetic process [GO:0060557]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein ADP-ribosylation [GO:0010835]; regulation of regulatory T cell differentiation [GO:0045589]; response to virus [GO:0009615]	activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular respiration [GO:1901857]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of iron ion import across plasma membrane [GO:1904440]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vitamin D biosynthetic process [GO:0060557]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein ADP-ribosylation [GO:0010835]; regulation of regulatory T cell differentiation [GO:0045589]; response to virus [GO:0009615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]	cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]
d1bcpc1_d5lzjd___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	toxin activity [GO:0090729]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d1bcpe__d1i4gb1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]			extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]
d1bcpe__d2c5ca___1			Proteobacteria		extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1bcph1_d1qnud___1			Proteobacteria		extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1bcs.1_d2bgna2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	serine-type carboxypeptidase activity [GO:0004185]; proteolysis involved in cellular protein catabolic process [GO:0051603]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	proteolysis involved in cellular protein catabolic process [GO:0051603]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	serine-type carboxypeptidase activity [GO:0004185]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1bcxa__d3vzja___1			Firmicutes	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d1bcxa__d5gala___1		Metazoa	Firmicutes	Chordata	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	xylan catabolic process [GO:0045493]	apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]
d1bcza__d1w45a___1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; blood coagulation [GO:0007596]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of serine-type endopeptidase activity [GO:1900004]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	blood coagulation [GO:0007596]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of serine-type endopeptidase activity [GO:1900004]	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]	actin filament binding [GO:0051015]; calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]
d1bd2d1_d4xccl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1bd4c__d2h06a1__1		Metazoa	Apicomplexa	Chordata	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]
d1bd4d__d1a96c___1			Apicomplexa	Proteobacteria	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; magnesium ion binding [GO:0000287]; xanthine phosphoribosyltransferase activity [GO:0000310]; GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]		cytosol [GO:0005829]; plasma membrane [GO:0005886]	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]	hypoxanthine phosphoribosyltransferase activity [GO:0004422]; magnesium ion binding [GO:0000287]; xanthine phosphoribosyltransferase activity [GO:0000310]
d1bd8a__d4hlla___1	Metazoa		Chordata		cyclin D2-CDK4 complex [GO:0097129]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]; autophagic cell death [GO:0048102]; cell cycle arrest [GO:0007050]; DNA synthesis involved in DNA repair [GO:0000731]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of phosphorylation [GO:0042326]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to retinoic acid [GO:0032526]; response to UV [GO:0009411]; response to vitamin D [GO:0033280]; sensory perception of sound [GO:0007605]		autophagic cell death [GO:0048102]; cell cycle arrest [GO:0007050]; DNA synthesis involved in DNA repair [GO:0000731]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of phosphorylation [GO:0042326]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to retinoic acid [GO:0032526]; response to UV [GO:0009411]; response to vitamin D [GO:0033280]; sensory perception of sound [GO:0007605]		cyclin D2-CDK4 complex [GO:0097129]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]	
d1bd9a__d1wkpd___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; phosphatidylethanolamine binding [GO:0008429]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; serine-type endopeptidase inhibitor activity [GO:0004867]; MAPK cascade [GO:0000165]; negative regulation of MAPK cascade [GO:0043409]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; phosphatidylethanolamine binding [GO:0008429]; cell differentiation [GO:0030154]; flower development [GO:0009908]; meristem determinacy [GO:0010022]; photoperiodism, flowering [GO:0048573]; positive regulation of flower development [GO:0009911]; regulation of flower development [GO:0009909]; regulation of stomatal movement [GO:0010119]	MAPK cascade [GO:0000165]; negative regulation of MAPK cascade [GO:0043409]	cell differentiation [GO:0030154]; flower development [GO:0009908]; meristem determinacy [GO:0010022]; photoperiodism, flowering [GO:0048573]; positive regulation of flower development [GO:0009911]; regulation of flower development [GO:0009909]; regulation of stomatal movement [GO:0010119]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]	ATP binding [GO:0005524]; enzyme binding [GO:0019899]; phosphatidylethanolamine binding [GO:0008429]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; serine-type endopeptidase inhibitor activity [GO:0004867]	phosphatidylethanolamine binding [GO:0008429]
d1bd9b__d2iqxa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; phosphatidylethanolamine binding [GO:0008429]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; serine-type endopeptidase inhibitor activity [GO:0004867]; MAPK cascade [GO:0000165]; negative regulation of MAPK cascade [GO:0043409]	apical part of cell [GO:0045177]; axon terminus [GO:0043679]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; rough endoplasmic reticulum [GO:0005791]; synaptic vesicle [GO:0008021]; ATP binding [GO:0005524]; kinase binding [GO:0019900]; lipid binding [GO:0008289]; mitogen-activated protein kinase binding [GO:0051019]; protein kinase binding [GO:0019901]; receptor serine/threonine kinase binding [GO:0033612]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; eating behavior [GO:0042755]; hippocampus development [GO:0021766]; MAPK cascade [GO:0000165]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of acetylcholine metabolic process [GO:0060409]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of neurotransmitter levels [GO:0001505]; regulation of the force of heart contraction [GO:0002026]; response to activity [GO:0014823]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to electrical stimulus [GO:0051602]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; response to wounding [GO:0009611]; sperm capacitation [GO:0048240]; spermatid development [GO:0007286]	MAPK cascade [GO:0000165]; negative regulation of MAPK cascade [GO:0043409]	aging [GO:0007568]; eating behavior [GO:0042755]; hippocampus development [GO:0021766]; MAPK cascade [GO:0000165]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of acetylcholine metabolic process [GO:0060409]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of neurotransmitter levels [GO:0001505]; regulation of the force of heart contraction [GO:0002026]; response to activity [GO:0014823]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to electrical stimulus [GO:0051602]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; response to wounding [GO:0009611]; spermatid development [GO:0007286]; sperm capacitation [GO:0048240]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	apical part of cell [GO:0045177]; axon terminus [GO:0043679]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; rough endoplasmic reticulum [GO:0005791]; synaptic vesicle [GO:0008021]	ATP binding [GO:0005524]; enzyme binding [GO:0019899]; phosphatidylethanolamine binding [GO:0008429]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; serine-type endopeptidase inhibitor activity [GO:0004867]	ATP binding [GO:0005524]; kinase binding [GO:0019900]; lipid binding [GO:0008289]; mitogen-activated protein kinase binding [GO:0051019]; protein kinase binding [GO:0019901]; receptor serine/threonine kinase binding [GO:0033612]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor binding [GO:0005102]
d1bd9b__d4bega1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; phosphatidylethanolamine binding [GO:0008429]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; serine-type endopeptidase inhibitor activity [GO:0004867]; MAPK cascade [GO:0000165]; negative regulation of MAPK cascade [GO:0043409]	extracellular region [GO:0005576]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]	MAPK cascade [GO:0000165]; negative regulation of MAPK cascade [GO:0043409]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; enzyme binding [GO:0019899]; phosphatidylethanolamine binding [GO:0008429]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; serine-type endopeptidase inhibitor activity [GO:0004867]	identical protein binding [GO:0042802]
d1bdab__d3a8ba___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; phosphoprotein binding [GO:0051219]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; blood coagulation [GO:0007596]; cellular protein modification process [GO:0006464]; fibrinolysis [GO:0042730]; negative regulation of proteolysis [GO:0045861]; plasminogen activation [GO:0031639]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; proteolysis [GO:0006508]; response to hypoxia [GO:0001666]; smooth muscle cell migration [GO:0014909]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; cellular protein modification process [GO:0006464]; fibrinolysis [GO:0042730]; negative regulation of proteolysis [GO:0045861]; plasminogen activation [GO:0031639]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; proteolysis [GO:0006508]; response to hypoxia [GO:0001666]; smooth muscle cell migration [GO:0014909]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]	digestion [GO:0007586]; proteolysis [GO:0006508]	apical part of cell [GO:0045177]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	phosphoprotein binding [GO:0051219]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1bdga2_d1t6ca2__1	Metazoa		Platyhelminthes	Aquificae	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	metal ion binding [GO:0046872]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]		cell [GO:0005623]		ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]	metal ion binding [GO:0046872]
d1bdha2_d4n0qc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]; negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]	amino acid transport [GO:0006865]	negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]	amino acid transport [GO:0006865]	cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]	
d1bdlb__d1bwab___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1bdma2_d3vphc2__1			Deinococcus-Thermus	Deinococcus-Thermus	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d1bdqa__d1k1ua___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1bdqa__d3pbza___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1bdrb__d5ozna___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1bdua__d5hs3f1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1bdxd2_d1dgsb1__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; Holliday junction helicase complex [GO:0009379]; Holliday junction resolvase complex [GO:0048476]; ATP binding [GO:0005524]; four-way junction DNA binding [GO:0000400]; four-way junction helicase activity [GO:0009378]; identical protein binding [GO:0042802]; protein homotetramerization [GO:0051289]; recombinational repair [GO:0000725]; response to radiation [GO:0009314]; SOS response [GO:0009432]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	protein homotetramerization [GO:0051289]; recombinational repair [GO:0000725]; response to radiation [GO:0009314]; SOS response [GO:0009432]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]; Holliday junction helicase complex [GO:0009379]; Holliday junction resolvase complex [GO:0048476]		ATP binding [GO:0005524]; four-way junction DNA binding [GO:0000400]; four-way junction helicase activity [GO:0009378]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]
d1bdya__d3rdja___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; ATP binding [GO:0005524]; calcium-independent protein kinase C activity [GO:0004699]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; TIR domain binding [GO:0070976]; aging [GO:0007568]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular response to angiotensin [GO:1904385]; cellular response to glucose starvation [GO:0042149]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; collagen metabolic process [GO:0032963]; D-aspartate import across plasma membrane [GO:0070779]; defense response to bacterium [GO:0042742]; intracellular signal transduction [GO:0035556]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of platelet aggregation [GO:0090331]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of glucose import [GO:0046326]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of superoxide anion generation [GO:0032930]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of phosphorylation [GO:0042325]; response to amino acid [GO:0043200]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; central nervous system neuron axonogenesis [GO:0021955]; establishment of protein localization [GO:0045184]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of heart contraction [GO:0045822]; negative regulation of translation [GO:0017148]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of dense core granule biogenesis [GO:2000707]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of platelet aggregation [GO:0090330]; regulation of receptor-mediated endocytosis [GO:0048259]; response to antibiotic [GO:0046677]; response to corticosterone [GO:0051412]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]	aging [GO:0007568]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular response to angiotensin [GO:1904385]; cellular response to glucose starvation [GO:0042149]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; collagen metabolic process [GO:0032963]; D-aspartate import across plasma membrane [GO:0070779]; defense response to bacterium [GO:0042742]; intracellular signal transduction [GO:0035556]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of platelet aggregation [GO:0090331]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of glucose import [GO:0046326]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of superoxide anion generation [GO:0032930]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of phosphorylation [GO:0042325]; response to amino acid [GO:0043200]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; central nervous system neuron axonogenesis [GO:0021955]; establishment of protein localization [GO:0045184]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of heart contraction [GO:0045822]; negative regulation of translation [GO:0017148]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of dense core granule biogenesis [GO:2000707]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of platelet aggregation [GO:0090330]; regulation of receptor-mediated endocytosis [GO:0048259]; response to antibiotic [GO:0046677]; response to corticosterone [GO:0051412]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; calcium-independent protein kinase C activity [GO:0004699]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; TIR domain binding [GO:0070976]	ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270]
d1be3a1_d1bgyb1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1be3a2_d3h1ha2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1be3d2_d3l73q1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1be3e1_d1g8jb___1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]
d1be4a__d3ee3f1__1	Metazoa		Chordata		cytosol [GO:0005829]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; lactation [GO:0007595]; nervous system development [GO:0007399]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; lactation [GO:0007595]; nervous system development [GO:0007399]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]		ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1be4a__d5yolh___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; lactation [GO:0007595]; nervous system development [GO:0007399]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; lactation [GO:0007595]; nervous system development [GO:0007399]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1be4c__d2hveb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; lactation [GO:0007595]; nervous system development [GO:0007399]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]; cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; lactation [GO:0007595]; nervous system development [GO:0007399]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]
d1be4c__d5yihb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; lactation [GO:0007595]; nervous system development [GO:0007399]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; lactation [GO:0007595]; nervous system development [GO:0007399]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1be6a__d1tk2a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1beaa__d5tviv___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	lipid binding [GO:0008289]; lipid transport [GO:0006869]		lipid transport [GO:0006869]	extracellular region [GO:0005576]		serine-type endopeptidase inhibitor activity [GO:0004867]	lipid binding [GO:0008289]
d1beba__d3o2ya___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]		cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	extracellular region [GO:0005576]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d1bebb__d4i3da___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cytoplasm [GO:0005737]; lipid binding [GO:0008289]; bioluminescence [GO:0008218]		bioluminescence [GO:0008218]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	lipid binding [GO:0008289]
d1beca1_d1lmkg1__1												
d1beca1_d5i1jl2__1												
d1beda__d3rpna___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; pathogenesis [GO:0009405]; protein folding [GO:0006457]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cell redox homeostasis [GO:0045454]; pathogenesis [GO:0009405]; protein folding [GO:0006457]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cell [GO:0005623]; periplasmic space [GO:0042597]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]
d1beka__d1ac8a___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1beka__d4m11c2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1bema__d3fjwa___1	Fungi	Fungi	Ascomycota	Basidiomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]
d1beoa__d2aiba___1					extracellular region [GO:0005576]; modulation by symbiont of host defense-related programmed cell death [GO:0034053]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; steroid binding [GO:0005496]; lipid transport [GO:0006869]; modulation by symbiont of host defense-related programmed cell death [GO:0034053]; pathogenesis [GO:0009405]	modulation by symbiont of host defense-related programmed cell death [GO:0034053]; pathogenesis [GO:0009405]	lipid transport [GO:0006869]; modulation by symbiont of host defense-related programmed cell death [GO:0034053]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		steroid binding [GO:0005496]
d1bepa__d4blka___1	Fungi	Fungi	Ascomycota	Basidiomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]
d1besa__d1itka2__1	Fungi		Ascomycota	Euryarchaeota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1beub__d4d96a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	D-cysteine desulfhydrase activity [GO:0019148]; D-amino acid metabolic process [GO:0046416]	tryptophan biosynthetic process [GO:0000162]	D-amino acid metabolic process [GO:0046416]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	D-cysteine desulfhydrase activity [GO:0019148]
d1bexa__d1kyac3__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1bexa__d1py0a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1bexb__d1kbwd1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	cell outer membrane [GO:0009279]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1beyl1_d3cdgb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1beyl2_d3kpre2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1beza__d4f60a___1			Proteobacteria	Actinobacteria	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	response to toxic substance [GO:0009636]			haloalkane dehalogenase activity [GO:0018786]	haloalkane dehalogenase activity [GO:0018786]
d1bf2a1_d4yeek___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; isoamylase activity [GO:0019156]; metal ion binding [GO:0046872]	apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]		fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]	isoamylase activity [GO:0019156]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]
d1bf2a3_d2bs9f2__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; isoamylase activity [GO:0019156]; metal ion binding [GO:0046872]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		isoamylase activity [GO:0019156]; metal ion binding [GO:0046872]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d1bf5a2_d3qync1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; CCR5 chemokine receptor binding [GO:0031730]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; nuclear hormone receptor binding [GO:0035257]; promoter-specific chromatin binding [GO:1990841]; protein homodimerization activity [GO:0042803]; protein phosphatase 2A binding [GO:0051721]; repressing transcription factor binding [GO:0070491]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin-like protein ligase binding [GO:0044389]; blood circulation [GO:0008015]; cellular response to insulin stimulus [GO:0032869]; cellular response to interferon-beta [GO:0035458]; cellular response to interferon-gamma [GO:0071346]; cellular response to organic cyclic compound [GO:0071407]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to virus [GO:0051607]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-21-mediated signaling pathway [GO:0038114]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; interleukin-9-mediated signaling pathway [GO:0038113]; macrophage derived foam cell differentiation [GO:0010742]; metanephric mesenchymal cell differentiation [GO:0072162]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; negative regulation by virus of viral protein levels in host cell [GO:0046725]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072308]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of transcription, DNA-templated [GO:0006355]; renal tubule development [GO:0061326]; response to cAMP [GO:0051591]; response to cytokine [GO:0034097]; response to hydrogen peroxide [GO:0042542]; response to interferon-beta [GO:0035456]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to peptide hormone [GO:0043434]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; rough endoplasmic reticulum [GO:0005791]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; WW domain binding [GO:0050699]; apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative cell aging [GO:0001302]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]	blood circulation [GO:0008015]; cellular response to insulin stimulus [GO:0032869]; cellular response to interferon-beta [GO:0035458]; cellular response to interferon-gamma [GO:0071346]; cellular response to organic cyclic compound [GO:0071407]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to virus [GO:0051607]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-21-mediated signaling pathway [GO:0038114]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; interleukin-9-mediated signaling pathway [GO:0038113]; macrophage derived foam cell differentiation [GO:0010742]; metanephric mesenchymal cell differentiation [GO:0072162]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; negative regulation by virus of viral protein levels in host cell [GO:0046725]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072308]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of transcription, DNA-templated [GO:0006355]; renal tubule development [GO:0061326]; response to cAMP [GO:0051591]; response to cytokine [GO:0034097]; response to hydrogen peroxide [GO:0042542]; response to interferon-beta [GO:0035456]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to peptide hormone [GO:0043434]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative cell aging [GO:0001302]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; rough endoplasmic reticulum [GO:0005791]	cadherin binding [GO:0045296]; CCR5 chemokine receptor binding [GO:0031730]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; nuclear hormone receptor binding [GO:0035257]; promoter-specific chromatin binding [GO:1990841]; protein homodimerization activity [GO:0042803]; protein phosphatase 2A binding [GO:0051721]; repressing transcription factor binding [GO:0070491]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin-like protein ligase binding [GO:0044389]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; WW domain binding [GO:0050699]
d1bf8a1_d2bvud___1		Metazoa	Proteobacteria	Nematoda (roundworms)	outer membrane-bounded periplasmic space [GO:0030288]; protein folding chaperone [GO:0044183]; cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]	cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]		outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]	protein folding chaperone [GO:0044183]	
d1bfba__d4xkia1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1bfca__d1k5ub___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1bfea__d1x5qa1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; myelin sheath abaxonal region [GO:0035748]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Scrib-APC-beta-catenin complex [GO:0034750]; synapse [GO:0045202]; cadherin binding [GO:0045296]; activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; auditory receptor cell stereocilium organization [GO:0060088]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; post-anal tail morphogenesis [GO:0036342]; protein localization to adherens junction [GO:0071896]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; wound healing [GO:0042060]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; auditory receptor cell stereocilium organization [GO:0060088]; cell-cell adhesion [GO:0098609]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; post-anal tail morphogenesis [GO:0036342]; protein localization to adherens junction [GO:0071896]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; wound healing [GO:0042060]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	basolateral plasma membrane [GO:0016323]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; myelin sheath abaxonal region [GO:0035748]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Scrib-APC-beta-catenin complex [GO:0034750]; synapse [GO:0045202]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]	cadherin binding [GO:0045296]
d1bfea__d2i6va1__1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type II protein secretion system complex [GO:0015627]; protein secretion [GO:0009306]; protein secretion by the type II secretion system [GO:0015628]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	protein secretion [GO:0009306]; protein secretion by the type II secretion system [GO:0015628]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type II protein secretion system complex [GO:0015627]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]	
d1bffa__d3fjca1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1bffa__d4p0jb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; antifungal humoral response [GO:0019732]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-6 production [GO:0032715]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	antifungal humoral response [GO:0019732]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-6 production [GO:0032715]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]	cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]
d1bfob1_d5u17h___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1bfob2_d1eeyb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1bfod1_d4x6dg2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1bfoe1_d3areb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bfoe2_d5ukol1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1bfof2_d2adfl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bfog1_d2a9mh___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1bfog2_d5gz0c1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1bfoh1_d3ngbf2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	structural molecule activity [GO:0005198]
d1bfra__d3pwqj1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	
d1bfrb__d4togb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1bfrc__d3bknl___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1bfre__d1s2za1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1bfrg__d3dhha___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	toluene catabolic process [GO:0042203]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1bfrh__d5l89m___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]
d1bfrm__d2jd7k___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d1bfrp__d3qd8m1__1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1bfrq__d3uoil___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1bfrr__d2z90d___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1bfru__d2d5kc1__1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1bfrx__d3oj5j___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d1bfsa__d3irca___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1bftb__d1my7b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]	actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]	actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]
d1bg0a1_d1u6ra1__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]	phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]	cytoplasm [GO:0005737]	extracellular space [GO:0005615]	arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d1bg0a1_d3l2fo1__1	Metazoa		Arthropoda		cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]		arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	
d1bg3a2_d4foeb3__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein-containing complex binding [GO:0044877]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mannose metabolic process [GO:0006013]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of anion channel activity [GO:0010359]; response to brassinosteroid [GO:0009741]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931]; response to ketamine [GO:1901986]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mannose metabolic process [GO:0006013]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of anion channel activity [GO:0010359]; response to brassinosteroid [GO:0009741]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931]; response to ketamine [GO:1901986]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1bg3a4_d1qhaa2__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein-containing complex binding [GO:0044877]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mannose metabolic process [GO:0006013]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of anion channel activity [GO:0010359]; response to brassinosteroid [GO:0009741]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931]; response to ketamine [GO:1901986]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mannose metabolic process [GO:0006013]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of anion channel activity [GO:0010359]; response to brassinosteroid [GO:0009741]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931]; response to ketamine [GO:1901986]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1bg3a4_d2e8aa2__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein-containing complex binding [GO:0044877]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mannose metabolic process [GO:0006013]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of anion channel activity [GO:0010359]; response to brassinosteroid [GO:0009741]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931]; response to ketamine [GO:1901986]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mannose metabolic process [GO:0006013]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of anion channel activity [GO:0010359]; response to brassinosteroid [GO:0009741]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931]; response to ketamine [GO:1901986]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]
d1bg3b4_d1glfo1__1	Metazoa		Chordata	Proteobacteria	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein-containing complex binding [GO:0044877]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mannose metabolic process [GO:0006013]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of anion channel activity [GO:0010359]; response to brassinosteroid [GO:0009741]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931]; response to ketamine [GO:1901986]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mannose metabolic process [GO:0006013]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of anion channel activity [GO:0010359]; response to brassinosteroid [GO:0009741]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931]; response to ketamine [GO:1901986]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d1bg4a__d1r86a1__1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d1bg6a2_d3hadb2__1		Metazoa	Actinobacteria	Chordata	coenzyme binding [GO:0050662]; opine dehydrogenase activity [GO:0047129]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	coenzyme binding [GO:0050662]; opine dehydrogenase activity [GO:0047129]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d1bgaa__d2gvya2__1		Fungi	Firmicutes	Ascomycota	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	cellulose catabolic process [GO:0030245]	carbohydrate catabolic process [GO:0016052]		cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1bgac__d2v3eb2__1		Metazoa	Firmicutes	Chordata	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	cellulose catabolic process [GO:0030245]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1bgga__d1e6xm___1		Viridiplantae	Firmicutes	Streptophyta	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]		vacuole [GO:0005773]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]
d1bgga__d2bvya2__1			Firmicutes	Actinobacteria	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]
d1bggc__d2vqua5__1			Firmicutes	Bacteroidetes	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	beta-mannosidase activity [GO:0004567]
d1bggd__d1e40a2__1			Firmicutes	Firmicutes	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1bgja2_d2iidd2__1		Metazoa	Proteobacteria	Chordata	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	benzoate catabolic process via hydroxylation [GO:0043640]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]		extracellular region [GO:0005576]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]
d1bgla5_d5g5ka1__1				Proteobacteria		cytoplasm [GO:0005737]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]		carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]		beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]
d1bglc2_d1jywc1__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1bgld3_d2vzvb1__1				Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1bgld5_d3fiza___1												
d1bgle2_d3vdac2__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1bgle4_d3t0ba5__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1bglf3_d2jkxa2__1		Fungi		Ascomycota		extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]				extracellular region [GO:0005576]		galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]
d1bglg3_d2x09b1__1				Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1bglg5_d4toqd___1		Viridiplantae		Streptophyta		amyloplast [GO:0009501]; calcium ion binding [GO:0005509]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]; seed germination [GO:0009845]; seedling development [GO:0090351]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]; seed germination [GO:0009845]; seedling development [GO:0090351]		amyloplast [GO:0009501]		calcium ion binding [GO:0005509]; chitinase activity [GO:0004568]
d1bglh2_d2vmfb1__1				Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]
d1bglh3_d1yq2d3__1				Actinobacteria		beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		beta-galactosidase complex [GO:0009341]		beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1bglh4_d2f1ba2__1		Metazoa		Arthropoda		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1bgmi3_d3acfa___1				Firmicutes		cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]				cellulase activity [GO:0008810]; metal ion binding [GO:0046872]
d1bgmi4_d3t0dd5__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1bgmi5_d1h1nb___1		Fungi		Ascomycota		cellulase activity [GO:0008810]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				cellulase activity [GO:0008810]
d1bgmi5_d2pwha1__1				Proteobacteria		isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d1bgmk1_d3t2pd4__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1bgmk2_d5a1aa2__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1bgmk4_d1yq2b4__1				Actinobacteria		beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		beta-galactosidase complex [GO:0009341]		beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1bgmk4_d3dx4a3__1		Metazoa		Arthropoda		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1bgml1_d2je8b2__1				Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]
d1bgml2_d3t2ob2__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1bgml4_d3t2qa5__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1bgmm5_d5n6sa___1				Thermotogae		beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]				beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1bgmn4_d3njxa1__1		Fungi		Ascomycota		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]		cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]
d1bgmo4_d3bvxa2__1		Metazoa		Arthropoda		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1bgmp3_d2qkgb3__1												
d1bgmp4_d1ojpa3__1				Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		cell wall [GO:0005618]; extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d1bgoa__d2hxzb___1	Metazoa	Metazoa	Chordata	Chordata	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d1bgpa__d5kqkb2__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1bgqa__d5m4ha___1	Fungi	Metazoa	Ascomycota	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1bgva2_d1nqth2__1		Metazoa	Firmicutes	Chordata	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase (NAD+) activity [GO:0004352]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1bgva2_d3aogc1__1			Firmicutes	Deinococcus-Thermus	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	cellular amino acid metabolic process [GO:0006520]			glutamate dehydrogenase (NAD+) activity [GO:0004352]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1bgyd2_d1ppjq1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1bgym2_d3l75a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1bgyn2_d3h1ja2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1bgyq1_d1z03b1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d1bh5c__d4kyhb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; pyruvate metabolic process [GO:0006090]; regulation of transcription by RNA polymerase II [GO:0006357]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; regulation of transcription by RNA polymerase II [GO:0006357]	carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; pyruvate metabolic process [GO:0006090]; regulation of transcription by RNA polymerase II [GO:0006357]	carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]	lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]
d1bhdb__d1dxxc2__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystrophin-associated glycoprotein complex [GO:0016010]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; growth cone [GO:0030426]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; protein kinase binding [GO:0019901]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]; muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; response to denervation involved in regulation of muscle adaptation [GO:0014894]	cell [GO:0005623]; cell surface [GO:0009986]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]; actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein localization [GO:0034613]; cellular protein-containing complex assembly [GO:0034622]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; response to denervation involved in regulation of muscle adaptation [GO:0014894]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein-containing complex assembly [GO:0034622]; cellular protein localization [GO:0034613]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	cell junction [GO:0030054]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystrophin-associated glycoprotein complex [GO:0016010]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; growth cone [GO:0030426]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]	cell [GO:0005623]; cell-substrate junction [GO:0030055]; cell surface [GO:0009986]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; protein kinase binding [GO:0019901]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]
d1bhdb__d3hora1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystrophin-associated glycoprotein complex [GO:0016010]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; growth cone [GO:0030426]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; protein kinase binding [GO:0019901]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]; muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; response to denervation involved in regulation of muscle adaptation [GO:0014894]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; response to denervation involved in regulation of muscle adaptation [GO:0014894]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	cell junction [GO:0030054]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystrophin-associated glycoprotein complex [GO:0016010]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; growth cone [GO:0030426]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; protein kinase binding [GO:0019901]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d1bhea__d1ia5a___1		Fungi	Proteobacteria	Ascomycota	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	polygalacturonase activity [GO:0004650]
d1bhea__d1o8ga___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]
d1bhga1_d3i3bc4__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	beta-galactosidase complex [GO:0009341]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1bhga3_d1r8lb___1	Metazoa		Chordata	Firmicutes	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	metabolic process [GO:0008152]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]		beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]
d1bhgb1_d1jz2d2__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	beta-galactosidase complex [GO:0009341]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1bhgb1_d2vjxa3__1	Metazoa		Chordata	Bacteroidetes	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]		beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	beta-mannosidase activity [GO:0004567]
d1bhgb2_d3vdac1__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	beta-galactosidase complex [GO:0009341]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1bhgb3_d3edka2__1	Metazoa		Chordata	Bacteroidetes	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]		beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d1bhha__d2eo6a1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; plasma membrane [GO:0005886]; SH3/SH2 adaptor activity [GO:0005070]; B cell activation [GO:0042113]; intracellular signal transduction [GO:0035556]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell activation [GO:0042113]; intracellular signal transduction [GO:0035556]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; plasma membrane [GO:0005886]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]	SH3/SH2 adaptor activity [GO:0005070]
d1bhhb__d1o4ma___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]
d1bhjb__d1nbia___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]	folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d1bhna__d4fkxb___1	Metazoa		Chordata		cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; nervous system development [GO:0007399]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; posttranscriptional regulation of gene expression [GO:0010608]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; nervous system development [GO:0007399]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; posttranscriptional regulation of gene expression [GO:0010608]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d1bhnc__d4anca___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; nervous system development [GO:0007399]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; nervous system development [GO:0007399]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]
d1bhnd__d6ay1a1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; nervous system development [GO:0007399]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; nervous system development [GO:0007399]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1bho1__d4ihka___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; sarcolemma [GO:0042383]; serine-type endopeptidase inhibitor activity [GO:0004867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	growth plate cartilage chondrocyte morphogenesis [GO:0003429]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; sarcolemma [GO:0042383]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1bhq1__d3gxba1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d1bhsa__d5k4qb___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]; estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]	estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]	coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]
d1bhwd__d3aama___1			Actinobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; zinc ion binding [GO:0008270]; DNA repair [GO:0006281]	D-xylose metabolic process [GO:0042732]	DNA repair [GO:0006281]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; zinc ion binding [GO:0008270]
d1bi7b__d3twwb1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]; astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]
d1bi7b__d4a63l1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]; astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1bi8b__d1s70b___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]; astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	A band [GO:0031672]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; PTW/PP1 phosphatase complex [GO:0072357]; Z disc [GO:0030018]; 14-3-3 protein binding [GO:0071889]; enzyme inhibitor activity [GO:0004857]; phosphatase regulator activity [GO:0019208]; protein kinase binding [GO:0019901]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; signal transduction [GO:0007165]	astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; signal transduction [GO:0007165]	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	A band [GO:0031672]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; PTW/PP1 phosphatase complex [GO:0072357]; Z disc [GO:0030018]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]	14-3-3 protein binding [GO:0071889]; enzyme inhibitor activity [GO:0004857]; phosphatase regulator activity [GO:0019208]; protein kinase binding [GO:0019901]
d1bifa2_d2a9jb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]
d1biha2_d3q3gj1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular space [GO:0005615]; innate immune response [GO:0045087]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	innate immune response [GO:0045087]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	extracellular space [GO:0005615]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]
d1bihb2_d3qnxa1__1	Metazoa		Arthropoda		extracellular space [GO:0005615]; innate immune response [GO:0045087]		innate immune response [GO:0045087]		extracellular space [GO:0005615]			
d1bihb4_d1dqqb2__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular space [GO:0005615]; innate immune response [GO:0045087]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	innate immune response [GO:0045087]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bihb4_d3b5hd2__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular space [GO:0005615]; innate immune response [GO:0045087]	acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	innate immune response [GO:0045087]	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	extracellular space [GO:0005615]	acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]		cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]
d1biia1_d4nccl1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1biia1_d5jiib1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1biib__d1jufa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1biib__d4nryl1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1bioa__d2nu2e___1	Metazoa		Chordata	Actinobacteria	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]	extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase activity [GO:0004252]
d1bita__d1y3ya___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1biwb__d5n2xe___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1bj1h1_d4apqd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	
d1bj1j1_d1aj7l1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bj1j2_d2j8ob1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1bj1k1_d2zokb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1bj1l2_d1rfdl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	
d1bj3a__d2m94a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]			extracellular region [GO:0005576]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]
d1bj5a1_d5id9a3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1bj5a2_d4j2va3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1bj5a3_d4lb9a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1bj7a__d3akma___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]	cytosol [GO:0005829]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]		intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	cytosol [GO:0005829]	small molecule binding [GO:0036094]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]
d1bjab__d2c6ya___1		Metazoa		Chordata	DNA binding [GO:0003677]	cell [GO:0005623]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; magnesium ion binding [GO:0000287]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; negative regulation of autophagy [GO:0010507]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter [GO:0035947]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; response to starvation [GO:0042594]		canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; negative regulation of autophagy [GO:0010507]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter [GO:0035947]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to starvation [GO:0042594]		cell [GO:0005623]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; magnesium ion binding [GO:0000287]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1bjea__d3s1jb___1	Metazoa		Chordata	Verrucomicrobia	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1bjfa__d1sl8a___1	Metazoa	Metazoa	Chordata	Cnidaria	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; clathrin binding [GO:0030276]; tubulin binding [GO:0015631]; calcium-mediated signaling [GO:0019722]; regulation of systemic arterial blood pressure [GO:0003073]	calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]	calcium-mediated signaling [GO:0019722]; regulation of systemic arterial blood pressure [GO:0003073]	bioluminescence [GO:0008218]			actin binding [GO:0003779]; calcium ion binding [GO:0005509]; clathrin binding [GO:0030276]; tubulin binding [GO:0015631]	calcium ion binding [GO:0005509]
d1bjga__d4ky8c2__1			Proteobacteria		cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]		dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]		cytosol [GO:0005829]		magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	
d1bjia__d1w8oa3__1			Negarnaviricota	Actinobacteria	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1bjka1_d1gvha2__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; heme binding [GO:0020037]; hydroperoxide reductase activity [GO:0032843]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular response to nitrosative stress [GO:0071500]; nitric oxide catabolic process [GO:0046210]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	oxidation-reduction process [GO:0055114]	cellular response to nitrosative stress [GO:0071500]; nitric oxide catabolic process [GO:0046210]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	phycobilisome [GO:0030089]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; heme binding [GO:0020037]; hydroperoxide reductase activity [GO:0032843]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1bjka1_d1kzla2__1		Fungi	Cyanobacteria	Ascomycota	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; nucleus [GO:0005634]; riboflavin synthase activity [GO:0004746]; riboflavin biosynthetic process [GO:0009231]	oxidation-reduction process [GO:0055114]	riboflavin biosynthetic process [GO:0009231]	phycobilisome [GO:0030089]	cytosol [GO:0005829]; nucleus [GO:0005634]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	riboflavin synthase activity [GO:0004746]
d1bjka2_d1sm4a2__1		Viridiplantae	Cyanobacteria	Streptophyta	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]	chloroplast [GO:0009507]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1bjma2_d3u0wl2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bjmb2_d3rewe___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1bjoa__d5vwqj___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563]; lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate [GO:0033359]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563]; lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate [GO:0033359]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1bjqh__d4avva___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	mannose binding [GO:0005537]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1bjxa__d4nhzn1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; procollagen-proline 4-dioxygenase complex [GO:0016222]; enzyme binding [GO:0019899]; integrin binding [GO:0005178]; peptide disulfide oxidoreductase activity [GO:0015037]; procollagen-proline 4-dioxygenase activity [GO:0004656]; protein disulfide isomerase activity [GO:0003756]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-7 [GO:0098761]; chylomicron assembly [GO:0034378]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; protein folding [GO:0006457]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976]; very-low-density lipoprotein particle assembly [GO:0034379]	transferase activity [GO:0016740]	cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-7 [GO:0098761]; chylomicron assembly [GO:0034378]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; protein folding [GO:0006457]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976]; very-low-density lipoprotein particle assembly [GO:0034379]		cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; procollagen-proline 4-dioxygenase complex [GO:0016222]		enzyme binding [GO:0019899]; integrin binding [GO:0005178]; peptide disulfide oxidoreductase activity [GO:0015037]; procollagen-proline 4-dioxygenase activity [GO:0004656]; protein disulfide isomerase activity [GO:0003756]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	transferase activity [GO:0016740]
d1bjya4_d1rkwa2__1				Firmicutes		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]		negative regulation of transcription, DNA-templated [GO:0045892]				DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1bjza1_d5ezga1__1			Proteobacteria	Actinobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d1bk1a__d3mw4c1__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	GABA-ergic synapse [GO:0098982]; integral component of membrane [GO:0016021]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; calcium channel regulator activity [GO:0005246]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle exocytosis [GO:2000300]; synapse assembly [GO:0007416]	xylan catabolic process [GO:0045493]	cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle exocytosis [GO:2000300]; synapse assembly [GO:0007416]	extracellular region [GO:0005576]	GABA-ergic synapse [GO:0098982]; integral component of membrane [GO:0016021]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]	endo-1,4-beta-xylanase activity [GO:0031176]	calcium channel regulator activity [GO:0005246]; metal ion binding [GO:0046872]
d1bk6b__d3b7ux1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; disordered domain specific binding [GO:0097718]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; NLS-bearing protein import into nucleus [GO:0006607]; proteasome localization [GO:0031144]; protein targeting to membrane [GO:0006612]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	NLS-bearing protein import into nucleus [GO:0006607]; proteasome localization [GO:0031144]; protein targeting to membrane [GO:0006612]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	disordered domain specific binding [GO:0097718]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1bkea1_d5x52b3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1bkea2_d4f5sa3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1bkgc__d4zswa___1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	biosynthetic process [GO:0009058]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	cytoplasm [GO:0005737]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]	(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]
d1bkha1_d4dhga2__1			Proteobacteria	Actinobacteria	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]	metal ion binding [GO:0046872]	cellular amino acid catabolic process [GO:0009063]				chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]	metal ion binding [GO:0046872]
d1bkob__d3hj3d2__1			Firmicutes		cytosol [GO:0005829]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]		dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]		cytosol [GO:0005829]		thymidylate synthase activity [GO:0004799]	
d1bkra__d4q59b1__1	Metazoa	Metazoa	Chordata	Chordata	axolemma [GO:0030673]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; nucleolus [GO:0005730]; postsynaptic density [GO:0014069]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390]	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390]	hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	axolemma [GO:0030673]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; nucleolus [GO:0005730]; postsynaptic density [GO:0014069]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]
d1bksb__d1v8za1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	tryptophan synthase activity [GO:0004834]	tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	tryptophan synthase activity [GO:0004834]
d1bkzb__d1w6qb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d1bl0a2_d1d5yd2__1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; protein homodimerization activity [GO:0042803]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; response to antibiotic [GO:0046677]		protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; protein homodimerization activity [GO:0042803]	DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]
d1bl4b__d2lj4a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear lumen [GO:0031981]; nucleus [GO:0005634]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	protein folding [GO:0006457]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear lumen [GO:0031981]; nucleus [GO:0005634]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1bl5a__d1itwa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]
d1bl9b1_d1cxaa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1blba2_d2k1xa1__1	Metazoa		Chordata	Euryarchaeota	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1blbc1_d3hzba___1	Metazoa		Chordata	Bacteroidetes	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1blbd1_d2k1wa1__1	Metazoa		Chordata	Euryarchaeota	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1blbd2_d2jdfa1__1	Metazoa	Metazoa	Chordata	Chordata	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; lens fiber cell morphogenesis [GO:0070309]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; lens fiber cell morphogenesis [GO:0070309]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d1blea__d2jzod___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]; glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]
d1blfa2_d1b3ga___1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	protein transport [GO:0015031]	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	peptide transmembrane transporter activity [GO:1904680]
d1blia1_d3vgda3__1			Firmicutes	Crenarchaeota	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]
d1blle1_d2fxka1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	Barr body [GO:0001740]; condensed chromosome [GO:0000793]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; sex chromatin [GO:0001739]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; enzyme binding [GO:0019899]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]; chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of response to oxidative stress [GO:1902883]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of response to oxidative stress [GO:1902884]; regulation of gene expression, epigenetic [GO:0040029]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]		chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of response to oxidative stress [GO:1902883]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of response to oxidative stress [GO:1902884]; regulation of gene expression, epigenetic [GO:0040029]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	Barr body [GO:0001740]; condensed chromosome [GO:0000793]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; sex chromatin [GO:0001739]	aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; enzyme binding [GO:0019899]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]
d1blna1_d4z5rl1__1		Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]		adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]		collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]
d1blnc1_d1iebd1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]		
d1blnd2_d3qpql1__1												
d1blra__d3mvfa___1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	vasodilation [GO:0042311]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d1blza__d1gp6a___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]; penicillin biosynthetic process [GO:0042318]	dioxygenase activity [GO:0051213]; L-ascorbic acid binding [GO:0031418]; leucocyanidin oxygenase activity [GO:0050589]; metal ion binding [GO:0046872]; anthocyanin-containing compound biosynthetic process [GO:0009718]; proanthocyanidin biosynthetic process [GO:0010023]; response to jasmonic acid [GO:0009753]; response to wounding [GO:0009611]; vacuole organization [GO:0007033]	penicillin biosynthetic process [GO:0042318]	anthocyanin-containing compound biosynthetic process [GO:0009718]; proanthocyanidin biosynthetic process [GO:0010023]; response to jasmonic acid [GO:0009753]; response to wounding [GO:0009611]; vacuole organization [GO:0007033]			dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]	dioxygenase activity [GO:0051213]; L-ascorbic acid binding [GO:0031418]; leucocyanidin oxygenase activity [GO:0050589]; metal ion binding [GO:0046872]
d1bm0a1_d1e7ga3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1bm0a1_d4f5ua3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1bm0a2_d5iiha3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1bm0b2_d4zbra3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1bm0b3_d1lota2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d1bm3h2_d6ehya1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1bm3l1_d3ehbd___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bm3l2_d1n3ng1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1bm3l2_d3wjla1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bm5a__d1fe3a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell periphery [GO:0071944]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; lipid binding [GO:0008289]; cell proliferation in forebrain [GO:0021846]; epithelial cell proliferation [GO:0050673]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]; triglyceride catabolic process [GO:0019433]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell proliferation in forebrain [GO:0021846]; epithelial cell proliferation [GO:0050673]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell-cell junction [GO:0005911]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	lipid binding [GO:0008289]
d1bmaa__d2iphb___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]
d1bmdb2_d2j5kd2__1			Deinococcus-Thermus	Euryarchaeota	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-malate dehydrogenase activity [GO:0030060]
d1bmdb2_d2xxja2__1			Deinococcus-Thermus	Deinococcus-Thermus	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d1bmfa3_d4dwjb___1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]	ATP synthesis coupled proton transport [GO:0015986]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]
d1bmfb1_d2qe7b3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1bmfc2_d5ik2f1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1bmfd2_d3oe7d1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1bmfe1_d3a5cd3__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1bmfe2_d5cdfa1__1	Metazoa		Chordata	Proteobacteria	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1bmfe3_d2eyqa4__1	Metazoa		Chordata	Proteobacteria	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cytosol [GO:0005829]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	ATP synthesis coupled proton transport [GO:0015986]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	cytosol [GO:0005829]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]
d1bmff1_d3a5cl3__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1bmff3_d2jizj2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1bmga__d2ojef1__1	Metazoa		Chordata	Tenericutes	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]			
d1bmga__d5fb8a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Flemming body [GO:0090543]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; CD4 receptor binding [GO:0042609]; cytokine activity [GO:0005125]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; leukocyte chemotaxis [GO:0030595]; regulation of calcium ion transport [GO:0051924]; viral process [GO:0016032]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; leukocyte chemotaxis [GO:0030595]; regulation of calcium ion transport [GO:0051924]; viral process [GO:0016032]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Flemming body [GO:0090543]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]		CD4 receptor binding [GO:0042609]; cytokine activity [GO:0005125]
d1bmm.1_d1jxp.1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1bmob1_d1gqmh___1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; nuclear matrix [GO:0016363]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; platelet alpha granule membrane [GO:0031092]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; extracellular matrix binding [GO:0050840]; bone development [GO:0060348]; cellular response to growth factor stimulus [GO:0071363]; extracellular matrix organization [GO:0030198]; heart development [GO:0007507]; inner ear development [GO:0048839]; lung development [GO:0030324]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; ossification [GO:0001503]; pigmentation [GO:0043473]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; receptor-mediated endocytosis [GO:0006898]; regulation of cell morphogenesis [GO:0022604]; regulation of synapse organization [GO:0050807]; response to cadmium ion [GO:0046686]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to gravity [GO:0009629]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	bone development [GO:0060348]; cellular response to growth factor stimulus [GO:0071363]; extracellular matrix organization [GO:0030198]; heart development [GO:0007507]; inner ear development [GO:0048839]; lung development [GO:0030324]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; ossification [GO:0001503]; pigmentation [GO:0043473]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; receptor-mediated endocytosis [GO:0006898]; regulation of cell morphogenesis [GO:0022604]; regulation of synapse organization [GO:0050807]; response to cadmium ion [GO:0046686]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to gravity [GO:0009629]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; wound healing [GO:0042060]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	basement membrane [GO:0005604]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; nuclear matrix [GO:0016363]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; platelet alpha granule membrane [GO:0031092]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; extracellular matrix binding [GO:0050840]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d1bmq.1_d1rhj.2__1	Metazoa	Metazoa	Chordata	Chordata	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; IPAF inflammasome complex [GO:0072557]; NLRP1 inflammasome complex [GO:0072558]; NLRP3 inflammasome complex [GO:0072559]; plasma membrane [GO:0005886]; protease inhibitor complex [GO:0097179]; protein-containing complex [GO:0032991]; CARD domain binding [GO:0050700]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to cytokine stimulus [GO:0071345]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; aspartic-type endopeptidase activity [GO:0004190]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; death receptor binding [GO:0005123]; peptidase activity [GO:0008233]; phospholipase A2 activator activity [GO:0016005]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; anterior neural tube closure [GO:0061713]; apoptotic DNA fragmentation [GO:0006309]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; axonal fasciculation [GO:0007413]; B cell homeostasis [GO:0001782]; cell fate commitment [GO:0045165]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to staurosporine [GO:0072734]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte differentiation [GO:0030218]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glial cell apoptotic process [GO:0034349]; heart development [GO:0007507]; hippo signaling [GO:0035329]; hippocampus development [GO:0021766]; intrinsic apoptotic signaling pathway in response to osmotic stress [GO:0008627]; keratinocyte differentiation [GO:0030216]; learning or memory [GO:0007611]; leukocyte apoptotic process [GO:0071887]; luteolysis [GO:0001554]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell proliferation [GO:0030889]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet formation [GO:0030220]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of neuron apoptotic process [GO:0043525]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647]; response to amino acid [GO:0043200]; response to cobalt ion [GO:0032025]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; sensory perception of sound [GO:0007605]; striated muscle cell differentiation [GO:0051146]; T cell homeostasis [GO:0043029]; wound healing [GO:0042060]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to cytokine stimulus [GO:0071345]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165]	anterior neural tube closure [GO:0061713]; apoptotic DNA fragmentation [GO:0006309]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; axonal fasciculation [GO:0007413]; B cell homeostasis [GO:0001782]; cell fate commitment [GO:0045165]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to staurosporine [GO:0072734]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte differentiation [GO:0030218]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glial cell apoptotic process [GO:0034349]; heart development [GO:0007507]; hippocampus development [GO:0021766]; hippo signaling [GO:0035329]; intrinsic apoptotic signaling pathway in response to osmotic stress [GO:0008627]; keratinocyte differentiation [GO:0030216]; learning or memory [GO:0007611]; leukocyte apoptotic process [GO:0071887]; luteolysis [GO:0001554]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell proliferation [GO:0030889]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet formation [GO:0030220]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of neuron apoptotic process [GO:0043525]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647]; response to amino acid [GO:0043200]; response to cobalt ion [GO:0032025]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; sensory perception of sound [GO:0007605]; striated muscle cell differentiation [GO:0051146]; T cell homeostasis [GO:0043029]; wound healing [GO:0042060]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; IPAF inflammasome complex [GO:0072557]; NLRP1 inflammasome complex [GO:0072558]; NLRP3 inflammasome complex [GO:0072559]; plasma membrane [GO:0005886]; protease inhibitor complex [GO:0097179]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	CARD domain binding [GO:0050700]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]	aspartic-type endopeptidase activity [GO:0004190]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; death receptor binding [GO:0005123]; peptidase activity [GO:0008233]; phospholipase A2 activator activity [GO:0016005]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]
d1bmsb__d2quxg1__1					T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	viral capsid [GO:0019028]	regulation of translation [GO:0006417]		T=3 icosahedral viral capsid [GO:0039617]	viral capsid [GO:0019028]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	
d1bmsc__d2c4qc___1					T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1bmv11_d2gsye___1					host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	host cell cytoplasm [GO:0030430]; T=13 icosahedral viral capsid [GO:0039621]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]	transport of virus in host, cell to cell [GO:0046740]		host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	host cell cytoplasm [GO:0030430]; T=13 icosahedral viral capsid [GO:0039621]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]
d1bmwa__d2jnza1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]	extracellular region [GO:0005576]			extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1bmzb__d4pwkb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1bn7a__d5t4tb___1			Actinobacteria	Proteobacteria	haloalkane dehalogenase activity [GO:0018786]	haloacetate dehalogenase activity [GO:0018785]					haloalkane dehalogenase activity [GO:0018786]	haloacetate dehalogenase activity [GO:0018785]
d1bnca2_d1w96b2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d1bnca2_d2r84b1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]
d1bncb1_d5mlka3__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbon fixation [GO:0015977]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionyl-CoA carboxylase activity [GO:0004658]
d1bncb2_d1iova1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1bnec__d1brkb___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1bngc__d2f5mb___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1bnia__d1gmpa___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1bnjb__d3dh2a___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1bnjc__d3wr2e___1		Fungi	Firmicutes	Basidiomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1bnlb__d3alua___1	Metazoa	Metazoa	Chordata	Echinodermata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; response to drug [GO:0042493]; response to hydrostatic pressure [GO:0051599]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; response to drug [GO:0042493]; response to hydrostatic pressure [GO:0051599]; visual perception [GO:0007601]		basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1bnma__d5jnad___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	anchored component of external side of plasma membrane [GO:0031362]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell surface [GO:0009986]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	anchored component of external side of plasma membrane [GO:0031362]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell surface [GO:0009986]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1bnoa__d4i2fa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1bnpa__d4qzda1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1bnra__d1rgfa___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1bnsa__d4j5kb___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1bnsc__d3d5gc___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1bnva__d1i9na___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1bo4a__d1yx0a1__1			Proteobacteria	Firmicutes	N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]					N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]
d1bo4b__d5g1zc1__1			Proteobacteria	Apicomplexa	N-acetyltransferase activity [GO:0008080]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]		N-terminal protein myristoylation [GO:0006499]			N-acetyltransferase activity [GO:0008080]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d1bo8a__d4iqba___1		Metazoa	Firmicutes	Nematoda (roundworms)	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]	cytoplasm [GO:0005737]		thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d1bo9a__d1bcza___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of endosome membrane [GO:0031313]; extrinsic component of external side of plasma membrane [GO:0031232]; extrinsic component of membrane [GO:0019898]; focal adhesion [GO:0005925]; lateral plasma membrane [GO:0016328]; mast cell granule [GO:0042629]; mitochondrial membrane [GO:0031966]; motile cilium [GO:0031514]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]; vesicle [GO:0031982]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; DNA/DNA annealing activity [GO:1990814]; phospholipase A2 inhibitor activity [GO:0019834]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; actin cytoskeleton reorganization [GO:0031532]; adaptive immune response [GO:0002250]; alpha-beta T cell differentiation [GO:0046632]; arachidonic acid secretion [GO:0050482]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cytokine-mediated signaling pathway [GO:0019221]; DNA duplex unwinding [GO:0032508]; endocrine pancreas development [GO:0031018]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gliogenesis [GO:0042063]; granulocyte chemotaxis [GO:0071621]; hepatocyte differentiation [GO:0070365]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; insulin secretion [GO:0030073]; keratinocyte differentiation [GO:0030216]; monocyte chemotaxis [GO:0002548]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of apoptotic process [GO:0043066]; negative regulation of exocytosis [GO:0045920]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; neutrophil clearance [GO:0097350]; neutrophil homeostasis [GO:0001780]; peptide cross-linking [GO:0018149]; phagocytosis [GO:0006909]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; positive regulation of vesicle fusion [GO:0031340]; positive regulation of wound healing [GO:0090303]; prolactin secretion [GO:0070459]; prostate gland development [GO:0030850]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of hormone secretion [GO:0046883]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-1 production [GO:0032652]; regulation of leukocyte migration [GO:0002685]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to interleukin-1 [GO:0070555]; response to peptide hormone [GO:0043434]; response to X-ray [GO:0010165]; signal transduction [GO:0007165]	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	actin cytoskeleton reorganization [GO:0031532]; adaptive immune response [GO:0002250]; alpha-beta T cell differentiation [GO:0046632]; arachidonic acid secretion [GO:0050482]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cytokine-mediated signaling pathway [GO:0019221]; DNA duplex unwinding [GO:0032508]; endocrine pancreas development [GO:0031018]; gliogenesis [GO:0042063]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; granulocyte chemotaxis [GO:0071621]; hepatocyte differentiation [GO:0070365]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; insulin secretion [GO:0030073]; keratinocyte differentiation [GO:0030216]; monocyte chemotaxis [GO:0002548]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of apoptotic process [GO:0043066]; negative regulation of exocytosis [GO:0045920]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; neutrophil clearance [GO:0097350]; neutrophil homeostasis [GO:0001780]; peptide cross-linking [GO:0018149]; phagocytosis [GO:0006909]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; positive regulation of vesicle fusion [GO:0031340]; positive regulation of wound healing [GO:0090303]; prolactin secretion [GO:0070459]; prostate gland development [GO:0030850]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of hormone secretion [GO:0046883]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-1 production [GO:0032652]; regulation of leukocyte migration [GO:0002685]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to interleukin-1 [GO:0070555]; response to peptide hormone [GO:0043434]; response to X-ray [GO:0010165]; signal transduction [GO:0007165]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of endosome membrane [GO:0031313]; extrinsic component of external side of plasma membrane [GO:0031232]; extrinsic component of membrane [GO:0019898]; focal adhesion [GO:0005925]; lateral plasma membrane [GO:0016328]; mast cell granule [GO:0042629]; mitochondrial membrane [GO:0031966]; motile cilium [GO:0031514]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]; vesicle [GO:0031982]	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]	cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; DNA/DNA annealing activity [GO:1990814]; phospholipase A2 inhibitor activity [GO:0019834]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]
d1boca__d2maza___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]			apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]
d1boga2_d1dqqa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bogb1_d1zlwm1__1	Metazoa		Chordata		extracellular region [GO:0005576]				extracellular region [GO:0005576]			
d1bogb2_d6ehvx2__1	Metazoa		Chordata		extracellular region [GO:0005576]				extracellular region [GO:0005576]			
d1boha1_d1c25a___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5S rRNA binding [GO:0008097]; thiosulfate sulfurtransferase activity [GO:0004792]; rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chaperone binding [GO:0051087]; phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; cellular response to UV [GO:0034644]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; protein deubiquitination [GO:0016579]; regulation of cell cycle [GO:0051726]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to radiation [GO:0009314]	rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; transsulfuration [GO:0019346]	cell division [GO:0051301]; cell population proliferation [GO:0008283]; cellular response to UV [GO:0034644]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitotic cell cycle [GO:0045931]; protein deubiquitination [GO:0016579]; regulation of cell cycle [GO:0051726]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to radiation [GO:0009314]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5S rRNA binding [GO:0008097]; thiosulfate sulfurtransferase activity [GO:0004792]	chaperone binding [GO:0051087]; phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]
d1boqa__d3tita___1			Proteobacteria		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular region [GO:0005576]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1bosa__d5lzia___1				Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1bosc__d1qoha___1				Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1bosg__d1l0xb1__1		Metazoa		Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	integral component of membrane [GO:0016021]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		extracellular region [GO:0005576]	integral component of membrane [GO:0016021]	toxin activity [GO:0090729]	
d1bosi__d5lzhe___1				Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1bosj__d1d1id___1					extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1bosr__d1b1za1__1				Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1boss__d1lt6l___1				Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1boto2_d5aqwa2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]
d1botz1_d1kaya1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d1botz2_d2zgzb2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	identical protein binding [GO:0042802]; plasmid partitioning [GO:0030541]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	plasmid partitioning [GO:0030541]	cytosol [GO:0005829]		ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]
d1boxa__d2sara___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1boya2_d6b24c___1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	integral component of plasma membrane [GO:0005887]; inorganic anion transmembrane transporter activity [GO:0015103]	activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]	integral component of plasma membrane [GO:0005887]	cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]	inorganic anion transmembrane transporter activity [GO:0015103]
d1bp1a1_d4m4db1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; specific granule lumen [GO:0035580]; lipopolysaccharide binding [GO:0001530]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response [GO:0045087]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of macrophage activation [GO:0043031]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]	cell surface [GO:0009986]; extracellular space [GO:0005615]; membrane [GO:0016020]; lipopeptide binding [GO:0071723]; lipopolysaccharide binding [GO:0001530]; lipoteichoic acid binding [GO:0070891]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of molecule of bacterial origin [GO:0032490]; innate immune response [GO:0045087]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; lipopolysaccharide transport [GO:0015920]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macromolecule localization [GO:0033036]; macrophage activation involved in immune response [GO:0002281]; negative regulation of tumor necrosis factor production [GO:0032720]; opsonization [GO:0008228]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytolysis [GO:0045919]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage activation [GO:0043032]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of respiratory burst involved in inflammatory response [GO:0060265]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of membrane permeability [GO:0090559]; response to lipopolysaccharide [GO:0032496]	antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response [GO:0045087]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of macrophage activation [GO:0043031]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]	acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of molecule of bacterial origin [GO:0032490]; innate immune response [GO:0045087]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lipopolysaccharide transport [GO:0015920]; macromolecule localization [GO:0033036]; macrophage activation involved in immune response [GO:0002281]; negative regulation of tumor necrosis factor production [GO:0032720]; opsonization [GO:0008228]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytolysis [GO:0045919]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage activation [GO:0043032]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of respiratory burst involved in inflammatory response [GO:0060265]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of membrane permeability [GO:0090559]; response to lipopolysaccharide [GO:0032496]	azurophil granule lumen [GO:0035578]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; specific granule lumen [GO:0035580]	cell surface [GO:0009986]; extracellular space [GO:0005615]; membrane [GO:0016020]	lipopolysaccharide binding [GO:0001530]	lipopeptide binding [GO:0071723]; lipopolysaccharide binding [GO:0001530]; lipoteichoic acid binding [GO:0070891]; signaling receptor binding [GO:0005102]
d1bp5b__d1mqgb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1bp6a__d1tdba___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d1bp7a__d1dq3a4__1	Viridiplantae		Chlorophyta	Euryarchaeota	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]	ATP binding [GO:0005524]; cobalamin binding [GO:0031419]; endonuclease activity [GO:0004519]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	intron homing [GO:0006314]	DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	chloroplast [GO:0009507]		endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; cobalamin binding [GO:0031419]; endonuclease activity [GO:0004519]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1bpl.1_d3ptmb___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]
d1bpna1_d4cpaa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1bpna2_d5cmsg___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]; negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]		negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]		aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]
d1bpob1_d1ee4a___1	Metazoa	Fungi	Chordata	Ascomycota	clathrin coat [GO:0030118]; clathrin coat of coated pit [GO:0030132]; clathrin coat of trans-Golgi network vesicle [GO:0030130]; clathrin complex [GO:0071439]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; extrinsic component of synaptic vesicle membrane [GO:0098850]; melanosome [GO:0042470]; sarcolemma [GO:0042383]; spindle [GO:0005819]; T-tubule [GO:0030315]; terminal bouton [GO:0043195]; ankyrin binding [GO:0030506]; clathrin light chain binding [GO:0032051]; heat shock protein binding [GO:0031072]; peptide binding [GO:0042277]; protein C-terminus binding [GO:0008022]; structural molecule activity [GO:0005198]; autophagy [GO:0006914]; clathrin coat assembly [GO:0048268]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; mitotic cell cycle [GO:0000278]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle endocytosis [GO:0048488]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; disordered domain specific binding [GO:0097718]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; NLS-bearing protein import into nucleus [GO:0006607]; proteasome localization [GO:0031144]; protein targeting to membrane [GO:0006612]	autophagy [GO:0006914]; clathrin coat assembly [GO:0048268]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; mitotic cell cycle [GO:0000278]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle endocytosis [GO:0048488]	NLS-bearing protein import into nucleus [GO:0006607]; proteasome localization [GO:0031144]; protein targeting to membrane [GO:0006612]	clathrin coat [GO:0030118]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; clathrin coat of coated pit [GO:0030132]; clathrin coat of trans-Golgi network vesicle [GO:0030130]; clathrin complex [GO:0071439]; extrinsic component of synaptic vesicle membrane [GO:0098850]; melanosome [GO:0042470]; sarcolemma [GO:0042383]; spindle [GO:0005819]; terminal bouton [GO:0043195]; T-tubule [GO:0030315]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	ankyrin binding [GO:0030506]; clathrin light chain binding [GO:0032051]; heat shock protein binding [GO:0031072]; peptide binding [GO:0042277]; protein C-terminus binding [GO:0008022]; structural molecule activity [GO:0005198]	disordered domain specific binding [GO:0097718]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]
d1bpwd__d5ek6f___1	Metazoa		Chordata	Crenarchaeota	cytosol [GO:0005829]; 4-trimethylammoniobutyraldehyde dehydrogenase activity [GO:0047105]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; carnitine biosynthetic process [GO:0045329]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	carnitine biosynthetic process [GO:0045329]		cytosol [GO:0005829]		4-trimethylammoniobutyraldehyde dehydrogenase activity [GO:0047105]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1bpya4_d4rwqa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 2'-5'-oligoadenylate synthetase activity [GO:0001730]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; purine nucleotide biosynthetic process [GO:0006164]; regulation of ribonuclease activity [GO:0060700]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; purine nucleotide biosynthetic process [GO:0006164]; regulation of ribonuclease activity [GO:0060700]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	2'-5'-oligoadenylate synthetase activity [GO:0001730]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]
d1bq3c__d3k4pa___1	Fungi	Fungi	Ascomycota	Ascomycota	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	extracellular region [GO:0005576]; 3-phytase activity [GO:0016158]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	phosphoglycerate mutase activity [GO:0004619]	3-phytase activity [GO:0016158]
d1bq3d__d1dkna___1	Fungi		Ascomycota	Proteobacteria	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	outer membrane-bounded periplasmic space [GO:0030288]; 4-phytase activity [GO:0008707]; acid phosphatase activity [GO:0003993]; inositol phosphate phosphatase activity [GO:0052745]; nucleotidase activity [GO:0008252]; sugar-phosphatase activity [GO:0050308]; cellular response to anoxia [GO:0071454]; cellular response to phosphate starvation [GO:0016036]; dephosphorylation [GO:0016311]; myo-inositol hexakisphosphate dephosphorylation [GO:0033518]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cellular response to anoxia [GO:0071454]; cellular response to phosphate starvation [GO:0016036]; dephosphorylation [GO:0016311]; myo-inositol hexakisphosphate dephosphorylation [GO:0033518]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	outer membrane-bounded periplasmic space [GO:0030288]	phosphoglycerate mutase activity [GO:0004619]	4-phytase activity [GO:0008707]; acid phosphatase activity [GO:0003993]; inositol phosphate phosphatase activity [GO:0052745]; nucleotidase activity [GO:0008252]; sugar-phosphatase activity [GO:0050308]
d1bq4b__d2hpab___1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]; adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	phosphoglycerate mutase activity [GO:0004619]	5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]
d1bq7b__d2o87a___1			Proteobacteria	Firmicutes	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d1bq7c__d1r4wd___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	epithelial cell differentiation [GO:0030855]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]
d1bq7d__d1u3ab___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d1bq7e__d4q5rc1__1		Metazoa	Proteobacteria	Arthropoda	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]		cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]		protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione transferase activity [GO:0004364]
d1bqba__d3fufa2__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1bqba__d5wr2a___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]				extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1bqca__d1hjqa___1		Fungi	Actinobacteria	Ascomycota	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]; cell wall macromolecule catabolic process [GO:0016998]	carbohydrate metabolic process [GO:0005975]	cell wall macromolecule catabolic process [GO:0016998]			mannan endo-1,4-beta-mannosidase activity [GO:0016985]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]
d1bqca__d2zida1__1			Actinobacteria	Firmicutes	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; glucan 1,6-alpha-glucosidase activity [GO:0043896]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		cytoplasm [GO:0005737]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]	glucan 1,6-alpha-glucosidase activity [GO:0043896]
d1bqea1_d4fk8b1__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]		ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1bqea2_d1qg0a2__1		Viridiplantae	Cyanobacteria	Streptophyta	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	photosynthesis [GO:0015979]	phycobilisome [GO:0030089]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]
d1bqga1_d4h83d2__1			Proteobacteria	Actinobacteria	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	metal ion binding [GO:0046872]	D-glucarate catabolic process [GO:0042838]				glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]
d1bqha1_d1a4ka1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bqhb__d3bp7b1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1bqhg__d3h9za1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bqhi1_d3dvnb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bqhk__d2fx8m1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	structural molecule activity [GO:0005198]
d1bqia__d1csb.1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]		cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]	cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]
d1bqll1_d1fn4b2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bqll2_d1mcqa1__1	Metazoa		Chordata		extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]		cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]		extracellular region [GO:0005576]		lysozyme activity [GO:0003796]	
d1bqly__d1cj6a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1bqoa__d1pe7a___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1bqob__d1zxva1__1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d1bqp.2_d3vkob___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d1bqqt__d2e2dc2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; intermediate filament cytoskeleton [GO:0045111]; macropinosome [GO:0044354]; melanosome [GO:0042470]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; metalloaminopeptidase activity [GO:0070006]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; astrocyte cell migration [GO:0043615]; branching morphogenesis of an epithelial tube [GO:0048754]; cell motility [GO:0048870]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; endodermal cell differentiation [GO:0035987]; endothelial cell proliferation [GO:0001935]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; head development [GO:0060322]; lung development [GO:0030324]; male gonad development [GO:0008584]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle development [GO:0001541]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of macrophage migration [GO:1905523]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein processing [GO:0010954]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein localization to plasma membrane [GO:1903076]; response to estrogen [GO:0043627]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to odorant [GO:1990834]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; skeletal system development [GO:0001501]; tissue remodeling [GO:0048771]; zymogen activation [GO:0031638]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	angiogenesis [GO:0001525]; astrocyte cell migration [GO:0043615]; branching morphogenesis of an epithelial tube [GO:0048754]; cell motility [GO:0048870]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; endodermal cell differentiation [GO:0035987]; endothelial cell proliferation [GO:0001935]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; head development [GO:0060322]; lung development [GO:0030324]; male gonad development [GO:0008584]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle development [GO:0001541]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of macrophage migration [GO:1905523]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein processing [GO:0010954]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein localization to plasma membrane [GO:1903076]; response to estrogen [GO:0043627]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to odorant [GO:1990834]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; skeletal system development [GO:0001501]; tissue remodeling [GO:0048771]; zymogen activation [GO:0031638]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; intermediate filament cytoskeleton [GO:0045111]; macropinosome [GO:0044354]; melanosome [GO:0042470]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; metalloaminopeptidase activity [GO:0070006]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1bqra__d4k9ja___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1bqsa2_d3of6c1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; integrin binding involved in cell-matrix adhesion [GO:0098640]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	integral component of membrane [GO:0016021]; negative regulation of thymocyte apoptotic process [GO:0070244]	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	negative regulation of thymocyte apoptotic process [GO:0070244]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	integrin binding involved in cell-matrix adhesion [GO:0098640]	
d1bqua1_d3bplc1__1	Metazoa	Metazoa	Chordata	Chordata	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	centriolar satellite [GO:0034451]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; interleukin-4 receptor activity [GO:0004913]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; immune response [GO:0006955]; immunoglobulin mediated immune response [GO:0016064]; negative regulation of T-helper 1 cell differentiation [GO:0045626]; ovulation [GO:0030728]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; production of molecular mediator involved in inflammatory response [GO:0002532]; regulation of cell population proliferation [GO:0042127]; response to estrogen [GO:0043627]; response to odorant [GO:1990834]; signal transduction [GO:0007165]	ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; immune response [GO:0006955]; immunoglobulin mediated immune response [GO:0016064]; negative regulation of T-helper 1 cell differentiation [GO:0045626]; ovulation [GO:0030728]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; production of molecular mediator involved in inflammatory response [GO:0002532]; regulation of cell population proliferation [GO:0042127]; response to estrogen [GO:0043627]; response to odorant [GO:1990834]; signal transduction [GO:0007165]	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	centriolar satellite [GO:0034451]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]	interleukin-4 receptor activity [GO:0004913]
d1bqva__d1lkyd___1		Metazoa		Chordata		cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription by RNA polymerase II [GO:0006357]; vitellogenesis [GO:0007296]		cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription by RNA polymerase II [GO:0006357]; vitellogenesis [GO:0007296]		cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleus [GO:0005634]		DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d1bqza__d1hdja___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein-containing complex assembly [GO:0065003]; response to heat [GO:0009408]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; sperm head [GO:0061827]; ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; protein folding chaperone [GO:0044183]; transcription corepressor activity [GO:0003714]; unfolded protein binding [GO:0051082]; chaperone cofactor-dependent protein refolding [GO:0051085]; forebrain development [GO:0030900]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; positive regulation of ATPase activity [GO:0032781]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]	chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein-containing complex assembly [GO:0065003]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; viral process [GO:0016032]	chaperone cofactor-dependent protein refolding [GO:0051085]; forebrain development [GO:0030900]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; positive regulation of ATPase activity [GO:0032781]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; sperm head [GO:0061827]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]	ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; protein folding chaperone [GO:0044183]; transcription corepressor activity [GO:0003714]; unfolded protein binding [GO:0051082]
d1br1d__d4jpzc___1	Metazoa	Metazoa	Chordata	Chordata	muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin filament [GO:0032982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin-dependent ATPase activity [GO:0030898]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; magnesium ion binding [GO:0000287]; microfilament motor activity [GO:0000146]; myosin II binding [GO:0045159]; myosin light chain binding [GO:0032027]; protein heterodimerization activity [GO:0046982]; structural constituent of muscle [GO:0008307]; cardiac muscle fiber development [GO:0048739]; elastic fiber assembly [GO:0048251]; myofibril assembly [GO:0030239]; skeletal muscle myosin thick filament assembly [GO:0030241]; smooth muscle contraction [GO:0006939]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cardiac muscle fiber development [GO:0048739]; elastic fiber assembly [GO:0048251]; myofibril assembly [GO:0030239]; skeletal muscle myosin thick filament assembly [GO:0030241]; smooth muscle contraction [GO:0006939]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin filament [GO:0032982]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	actin binding [GO:0003779]; actin-dependent ATPase activity [GO:0030898]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; magnesium ion binding [GO:0000287]; microfilament motor activity [GO:0000146]; myosin II binding [GO:0045159]; myosin light chain binding [GO:0032027]; protein heterodimerization activity [GO:0046982]; structural constituent of muscle [GO:0008307]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1br1f__d1fbva1__1	Metazoa	Metazoa	Chordata	Chordata	muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin filament [GO:0032982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin-dependent ATPase activity [GO:0030898]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; magnesium ion binding [GO:0000287]; microfilament motor activity [GO:0000146]; myosin II binding [GO:0045159]; myosin light chain binding [GO:0032027]; protein heterodimerization activity [GO:0046982]; structural constituent of muscle [GO:0008307]; cardiac muscle fiber development [GO:0048739]; elastic fiber assembly [GO:0048251]; myofibril assembly [GO:0030239]; skeletal muscle myosin thick filament assembly [GO:0030241]; smooth muscle contraction [GO:0006939]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle phase transition [GO:0044770]; cell population proliferation [GO:0008283]; cellular protein modification process [GO:0006464]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to steroid hormone stimulus [GO:0071383]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein K11-linked ubiquitination [GO:0070979]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]	cardiac muscle fiber development [GO:0048739]; elastic fiber assembly [GO:0048251]; myofibril assembly [GO:0030239]; skeletal muscle myosin thick filament assembly [GO:0030241]; smooth muscle contraction [GO:0006939]	cell cycle phase transition [GO:0044770]; cell population proliferation [GO:0008283]; cellular protein modification process [GO:0006464]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to steroid hormone stimulus [GO:0071383]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein K11-linked ubiquitination [GO:0070979]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]	muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin filament [GO:0032982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151]	actin binding [GO:0003779]; actin-dependent ATPase activity [GO:0030898]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; magnesium ion binding [GO:0000287]; microfilament motor activity [GO:0000146]; myosin II binding [GO:0045159]; myosin light chain binding [GO:0032027]; protein heterodimerization activity [GO:0046982]; structural constituent of muscle [GO:0008307]	ATP binding [GO:0005524]; enzyme binding [GO:0019899]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]; ubiquitin-protein transferase activity [GO:0004842]
d1br4b__d4pe0a___1	Metazoa	Metazoa	Chordata	Chordata	muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin filament [GO:0032982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin-dependent ATPase activity [GO:0030898]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; magnesium ion binding [GO:0000287]; microfilament motor activity [GO:0000146]; myosin II binding [GO:0045159]; myosin light chain binding [GO:0032027]; protein heterodimerization activity [GO:0046982]; structural constituent of muscle [GO:0008307]; cardiac muscle fiber development [GO:0048739]; elastic fiber assembly [GO:0048251]; myofibril assembly [GO:0030239]; skeletal muscle myosin thick filament assembly [GO:0030241]; smooth muscle contraction [GO:0006939]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	cardiac muscle fiber development [GO:0048739]; elastic fiber assembly [GO:0048251]; myofibril assembly [GO:0030239]; skeletal muscle myosin thick filament assembly [GO:0030241]; smooth muscle contraction [GO:0006939]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin filament [GO:0032982]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	actin binding [GO:0003779]; actin-dependent ATPase activity [GO:0030898]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; magnesium ion binding [GO:0000287]; microfilament motor activity [GO:0000146]; myosin II binding [GO:0045159]; myosin light chain binding [GO:0032027]; protein heterodimerization activity [GO:0046982]; structural constituent of muscle [GO:0008307]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1brbe__d1wykc___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1brea__d1um5h2__1		Metazoa		Chordata								
d1breb__d1xf2a2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bred__d1mpal1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bref__d5mevl2__1		Metazoa		Chordata		Bcl-2 family protein complex [GO:0097136]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; BH3 domain binding [GO:0051434]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein transmembrane transporter activity [GO:0008320]; cell fate determination [GO:0001709]; cellular homeostasis [GO:0019725]; cytokine-mediated signaling pathway [GO:0019221]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism development [GO:0007275]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; regulation of response to DNA damage stimulus [GO:2001020]; response to cytokine [GO:0034097]		cell fate determination [GO:0001709]; cellular homeostasis [GO:0019725]; cytokine-mediated signaling pathway [GO:0019221]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism development [GO:0007275]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; regulation of response to DNA damage stimulus [GO:2001020]; response to cytokine [GO:0034097]		Bcl-2 family protein complex [GO:0097136]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		BH3 domain binding [GO:0051434]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein transmembrane transporter activity [GO:0008320]
d1brga__d1ucka___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1brgc__d1banc___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1brjb__d1t2hb___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1brkc__d1bsca___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1brlb__d3b9nb___1			Proteobacteria	Firmicutes	alkanal monooxygenase (FMN-linked) activity [GO:0047646]; bioluminescence [GO:0008218]	monooxygenase activity [GO:0004497]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	bioluminescence [GO:0008218]				alkanal monooxygenase (FMN-linked) activity [GO:0047646]	monooxygenase activity [GO:0004497]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1brnm__d3wr2a___1		Fungi	Firmicutes	Basidiomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1brpa__d3fiqa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; protein heterodimerization activity [GO:0046982]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]; cardiac muscle tissue development [GO:0048738]; embryonic organ morphogenesis [GO:0048562]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; female genitalia morphogenesis [GO:0048807]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; lung development [GO:0030324]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; urinary bladder development [GO:0060157]; uterus development [GO:0060065]; vagina development [GO:0060068]; visual perception [GO:0007601]	extracellular region [GO:0005576]; odorant binding [GO:0005549]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cardiac muscle tissue development [GO:0048738]; embryonic organ morphogenesis [GO:0048562]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; female genitalia morphogenesis [GO:0048807]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; lung development [GO:0030324]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; urinary bladder development [GO:0060157]; uterus development [GO:0060065]; vagina development [GO:0060068]; visual perception [GO:0007601]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	protein heterodimerization activity [GO:0046982]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	odorant binding [GO:0005549]; small molecule binding [GO:0036094]
d1brqa__d2a0aa1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; protein heterodimerization activity [GO:0046982]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]; cardiac muscle tissue development [GO:0048738]; embryonic organ morphogenesis [GO:0048562]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; female genitalia morphogenesis [GO:0048807]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; lung development [GO:0030324]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; urinary bladder development [GO:0060157]; uterus development [GO:0060065]; vagina development [GO:0060068]; visual perception [GO:0007601]	lipid binding [GO:0008289]	cardiac muscle tissue development [GO:0048738]; embryonic organ morphogenesis [GO:0048562]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; female genitalia morphogenesis [GO:0048807]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; lung development [GO:0030324]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; urinary bladder development [GO:0060157]; uterus development [GO:0060065]; vagina development [GO:0060068]; visual perception [GO:0007601]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]		protein heterodimerization activity [GO:0046982]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	lipid binding [GO:0008289]
d1brwa1_d1khdc1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	tryptophan biosynthetic process [GO:0000162]			metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]
d1brwb2_d5ep8a2__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]	metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1brwb3_d1azya3__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	cytosol [GO:0005829]; membrane [GO:0016020]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]	pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]		cytosol [GO:0005829]; membrane [GO:0016020]	metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1bs1a__d1exma3__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; ATP binding [GO:0005524]; dethiobiotin synthase activity [GO:0004141]; magnesium ion binding [GO:0000287]; biotin biosynthetic process [GO:0009102]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	biotin biosynthetic process [GO:0009102]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; dethiobiotin synthase activity [GO:0004141]; magnesium ion binding [GO:0000287]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1bs2a1_d4mw1b2__1	Fungi		Ascomycota		cytosol [GO:0005829]; mitochondrion [GO:0005739]; arginine-tRNA ligase activity [GO:0004814]; ATP binding [GO:0005524]; arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543]	methionyl-tRNA aminoacylation [GO:0006431]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	arginine-tRNA ligase activity [GO:0004814]; ATP binding [GO:0005524]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]
d1bs3a2_d4h3eb2__1			Actinobacteria		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1bs5a__d4je7a1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; mitochondrion [GO:0005739]; plant-type cell wall [GO:0009505]; metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; co-translational protein modification [GO:0043686]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; translation [GO:0006412]	cytosol [GO:0005829]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; mitochondrion [GO:0005739]; plant-type cell wall [GO:0009505]	ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d1bs5b__d4dr9c___1			Proteobacteria	Cyanobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	translation [GO:0006412]	cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d1bs5c__d1vevb___1			Proteobacteria	Spirochaetes	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d1bsdb__d1hyfa___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1bsdb__d1pyla___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1bsdc__d1jbsb___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]; negative regulation of translation [GO:0017148]		negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1bsea__d3agna___1		Fungi	Firmicutes	Basidiomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]			extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d1bsec__d1brgb___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1bsia2_d1fp9a___1	Metazoa		Chordata	Deinococcus-Thermus	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]
d1bsma2_d1n0jb2__1		Metazoa	Actinobacteria	Chordata	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1bsmb2_d1gv3b2__1			Actinobacteria	Cyanobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1bsoa__d5f6ba___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]		epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1bszc__d1ws1a___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d1bt6a__d1qiwa___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of plasma membrane [GO:0019897]; calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; membrane raft assembly [GO:0001765]; positive regulation of binding [GO:0051099]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; response to drug [GO:0042493]; vesicle budding from membrane [GO:0006900]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]; calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]; calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	membrane raft assembly [GO:0001765]; positive regulation of binding [GO:0051099]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; response to drug [GO:0042493]; vesicle budding from membrane [GO:0006900]	calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of plasma membrane [GO:0019897]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]	calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]
d1bt6b__d1y0vl1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of plasma membrane [GO:0019897]; calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; membrane raft assembly [GO:0001765]; positive regulation of binding [GO:0051099]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; response to drug [GO:0042493]; vesicle budding from membrane [GO:0006900]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	membrane raft assembly [GO:0001765]; positive regulation of binding [GO:0051099]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; response to drug [GO:0042493]; vesicle budding from membrane [GO:0006900]	calcium-mediated signaling [GO:0019722]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of plasma membrane [GO:0019897]		calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]
d1bt8a1_d3ak1c1__1			Actinobacteria	Crenarchaeota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1bt8b1_d3evkc1__1			Actinobacteria	Crenarchaeota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1bth.1_d2gt8a___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1btja__d4z7eb___1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; SOS response [GO:0009432]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	SOS response [GO:0009432]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	transmembrane transporter activity [GO:0022857]
d1btkb__d2loxa1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein tyrosine kinase activity [GO:0004713]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; B cell affinity maturation [GO:0002344]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; cell maturation [GO:0048469]; cellular response to interleukin-7 [GO:0098761]; cellular response to molecule of fungal origin [GO:0071226]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; histamine secretion by mast cell [GO:0002553]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; mesoderm development [GO:0007498]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cytokine production [GO:0001818]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type III hypersensitivity [GO:0001805]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of B cell apoptotic process [GO:0002902]; regulation of B cell cytokine production [GO:0002721]	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]; nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; B cell affinity maturation [GO:0002344]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; cell maturation [GO:0048469]; cellular response to interleukin-7 [GO:0098761]; cellular response to molecule of fungal origin [GO:0071226]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; histamine secretion by mast cell [GO:0002553]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; mesoderm development [GO:0007498]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cytokine production [GO:0001818]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type III hypersensitivity [GO:0001805]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of B cell apoptotic process [GO:0002902]; regulation of B cell cytokine production [GO:0002721]	nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein tyrosine kinase activity [GO:0004713]	phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]
d1btna__d1gg3a2__1	Metazoa	Metazoa	Chordata	Chordata	axolemma [GO:0030673]; cortical cytoskeleton [GO:0030863]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin [GO:0008091]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; structural constituent of cytoskeleton [GO:0005200]; actin filament capping [GO:0051693]; common-partner SMAD protein phosphorylation [GO:0007182]; Golgi to plasma membrane protein transport [GO:0043001]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	actin filament capping [GO:0051693]; common-partner SMAD protein phosphorylation [GO:0007182]; Golgi to plasma membrane protein transport [GO:0043001]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390]	actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	axolemma [GO:0030673]; cortical cytoskeleton [GO:0030863]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin [GO:0008091]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; structural constituent of cytoskeleton [GO:0005200]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]
d1btob2_d5ixyb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1btoc2_d1qlja2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]	cytosol [GO:0005829]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1btua__d1wyka___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1btwa__d2qida___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	
d1btya__d1jima___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1bu3a__d1topa___1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]		regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]		troponin complex [GO:0005861]	calcium ion binding [GO:0005509]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]
d1bu4a__d1i2ga___1	Fungi	Fungi	Ascomycota	Ascomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1bu5a__d1ychb1__1			Proteobacteria	Firmicutes	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1bu5b__d3gfsb___1			Proteobacteria	Firmicutes	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]				cytosol [GO:0005829]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d1bu6o1_d3sjha2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytosol [GO:0005829]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d1bu6x2_d2qwoa1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d1bu6z1_d2p3rd4__1			Proteobacteria		cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]		cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]		cytosol [GO:0005829]		ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	
d1bu6z2_d2d4wa1__1			Proteobacteria		cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]		cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]		cytosol [GO:0005829]		ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	
d1bu7b__d4dnza___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]			cytoplasm [GO:0005737]		aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1bu9a__d5o2tb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]; cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of phosphorylation [GO:0042326]; oligodendrocyte differentiation [GO:0048709]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]; actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of phosphorylation [GO:0042326]; oligodendrocyte differentiation [GO:0048709]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]	GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]
d1buic__d1c78b___1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; other organism cell membrane [GO:0044218]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; Schaffer collateral - CA1 synapse [GO:0098685]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; kinase binding [GO:0019900]; proteasome core complex binding [GO:1904854]; protein antigen binding [GO:1990405]; protein domain specific binding [GO:0019904]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; extracellular matrix disassembly [GO:0022617]; fibrinolysis [GO:0042730]; interaction with symbiont [GO:0051702]; interaction with symbiont via secreted substance [GO:0052213]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of fibrinolysis [GO:0051918]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trophoblast giant cell differentiation [GO:0060707]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]; plasminogen activation [GO:0031639]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; extracellular matrix disassembly [GO:0022617]; fibrinolysis [GO:0042730]; interaction with symbiont [GO:0051702]; interaction with symbiont via secreted substance [GO:0052213]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of fibrinolysis [GO:0051918]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trophoblast giant cell differentiation [GO:0060707]	pathogenesis [GO:0009405]; plasminogen activation [GO:0031639]	blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; other organism cell membrane [GO:0044218]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; Schaffer collateral - CA1 synapse [GO:0098685]	extracellular region [GO:0005576]	apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; kinase binding [GO:0019900]; proteasome core complex binding [GO:1904854]; protein antigen binding [GO:1990405]; protein domain specific binding [GO:0019904]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	
d1buja__d1bscb___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1bupa1_d3djca2__1	Metazoa		Chordata	Proteobacteria	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	coenzyme A biosynthetic process [GO:0015937]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d1bupa2_d5wfnb1__1	Metazoa	Metazoa	Chordata	Arthropoda	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]
d1buqa__d1sjwa___1			Proteobacteria	Actinobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	polyketide metabolic process [GO:0030638]	steroid metabolic process [GO:0008202]	polyketide metabolic process [GO:0030638]			steroid delta-isomerase activity [GO:0004769]	
d1burb3_d4f0ma1__1				Rhodophyta		chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]		reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1buru__d1rcof___1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]		magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1buxc__d3eica1__1					cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1bv1a__d5aewm2__1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]		abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1bv3a__d5jn1a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1bv5a__d2a24a___1		Metazoa		Chordata		cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]		angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]		cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]		DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d1bv7a__d5p68a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	aspartic-type endopeptidase activity [GO:0004190]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1bv7b__d2igyb___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1bv9b__d4rvxd___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	aspartic-type endopeptidase activity [GO:0004190]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1bveb__d5p6ba___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	aspartic-type endopeptidase activity [GO:0004190]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1bvha__d1p8aa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]			cytoplasm [GO:0005737]		acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d1bvka__d5t5nf2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]; chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1bvkc__d1l10a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1bvla1_d1indl1__1												
d1bvnp1_d2fhca4__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]	plasma membrane [GO:0005886]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]
d1bvoa__d5ab9b___1	Metazoa	Metazoa	Arthropoda	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1bvp12_d4wa2b1__1				Negarnaviricota	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]; host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]; fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]	host cell surface receptor binding [GO:0046789]
d1bvp22_d4uo7a___1				Negarnaviricota	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]; host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]; fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]	host cell surface receptor binding [GO:0046789]
d1bvp42_d1qhda2__1					viral envelope [GO:0019031]; viral outer capsid [GO:0039624]; host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]; fusion of virus membrane with host plasma membrane [GO:0019064]	T=13 icosahedral viral capsid [GO:0039621]; viral envelope [GO:0019031]; viral intermediate capsid [GO:0039626]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]; fusion of virus membrane with host plasma membrane [GO:0019064]	fusion of virus membrane with host plasma membrane [GO:0019064]	fusion of virus membrane with host plasma membrane [GO:0019064]	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]	T=13 icosahedral viral capsid [GO:0039621]; viral envelope [GO:0019031]; viral intermediate capsid [GO:0039626]	host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]	host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1bvp52_d4nrka___1				Negarnaviricota	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]; host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]; fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]	host cell surface receptor binding [GO:0046789]
d1bvra__d2egga2__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cell wall [GO:0005618]; plasma membrane [GO:0005886]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1bvrd__d1hdcb___1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; C21-steroid hormone metabolic process [GO:0008207]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	C21-steroid hormone metabolic process [GO:0008207]	cell wall [GO:0005618]; plasma membrane [GO:0005886]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]
d1bvse2_d1bdxb2__1			Actinobacteria	Proteobacteria	Holliday junction helicase complex [GO:0009379]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	cytoplasm [GO:0005737]; Holliday junction helicase complex [GO:0009379]; Holliday junction resolvase complex [GO:0048476]; ATP binding [GO:0005524]; four-way junction DNA binding [GO:0000400]; four-way junction helicase activity [GO:0009378]; identical protein binding [GO:0042802]; protein homotetramerization [GO:0051289]; recombinational repair [GO:0000725]; response to radiation [GO:0009314]; SOS response [GO:0009432]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	protein homotetramerization [GO:0051289]; recombinational repair [GO:0000725]; response to radiation [GO:0009314]; SOS response [GO:0009432]	Holliday junction helicase complex [GO:0009379]	cytoplasm [GO:0005737]; Holliday junction helicase complex [GO:0009379]; Holliday junction resolvase complex [GO:0048476]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]	ATP binding [GO:0005524]; four-way junction DNA binding [GO:0000400]; four-way junction helicase activity [GO:0009378]; identical protein binding [GO:0042802]
d1bvsf2_d1dgsa1__1			Actinobacteria	Deinococcus-Thermus	Holliday junction helicase complex [GO:0009379]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	Holliday junction helicase complex [GO:0009379]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]
d1bvua1_d3tzhd___1			Euryarchaeota		cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]		cytoplasm [GO:0005737]		glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	
d1bvua2_d3aogg1__1			Euryarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]		glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1bvub1_d1nqth1__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytoplasm [GO:0005737]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1bvuc2_d1nr7g2__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytoplasm [GO:0005737]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1bvuc2_d3k92f1__1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]		glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	glutamate dehydrogenase (NAD+) activity [GO:0004352]
d1bvud2_d1p77a2__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1bvue1_d3l77a1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	oxidoreductase activity [GO:0016491]	cellular amino acid metabolic process [GO:0006520]		cytoplasm [GO:0005737]		glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	oxidoreductase activity [GO:0016491]
d1bvue2_d3mvqd1__1			Euryarchaeota		cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]		cytoplasm [GO:0005737]		glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	
d1bvuf2_d4fccg1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]		glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1bvya__d5ofqa___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]			cytoplasm [GO:0005737]		aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1bvyb__d4g3jb___1			Firmicutes		cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d1bvyf__d4qoga___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1bvzb3_d1ghop5__1			Firmicutes		metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	
d1bwda__d9jdwa___1		Metazoa	Actinobacteria	Chordata	scyllo-inosamine-4-phosphate amidinotransferase activity [GO:0015069]; streptomycin biosynthetic process [GO:0019872]	extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; amidinotransferase activity [GO:0015067]; glycine amidinotransferase activity [GO:0015068]; creatine biosynthetic process [GO:0006601]; creatine metabolic process [GO:0006600]; learning or memory [GO:0007611]; multicellular organism development [GO:0007275]; muscle atrophy [GO:0014889]; positive regulation of cold-induced thermogenesis [GO:0120162]	streptomycin biosynthetic process [GO:0019872]	creatine biosynthetic process [GO:0006601]; creatine metabolic process [GO:0006600]; learning or memory [GO:0007611]; multicellular organism development [GO:0007275]; muscle atrophy [GO:0014889]; positive regulation of cold-induced thermogenesis [GO:0120162]		extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	scyllo-inosamine-4-phosphate amidinotransferase activity [GO:0015069]	amidinotransferase activity [GO:0015067]; glycine amidinotransferase activity [GO:0015068]
d1bwdb__d2jdwa___1		Metazoa	Actinobacteria	Chordata	scyllo-inosamine-4-phosphate amidinotransferase activity [GO:0015069]; streptomycin biosynthetic process [GO:0019872]	extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; amidinotransferase activity [GO:0015067]; glycine amidinotransferase activity [GO:0015068]; creatine biosynthetic process [GO:0006601]; creatine metabolic process [GO:0006600]; learning or memory [GO:0007611]; multicellular organism development [GO:0007275]; muscle atrophy [GO:0014889]; positive regulation of cold-induced thermogenesis [GO:0120162]	streptomycin biosynthetic process [GO:0019872]	creatine biosynthetic process [GO:0006601]; creatine metabolic process [GO:0006600]; learning or memory [GO:0007611]; multicellular organism development [GO:0007275]; muscle atrophy [GO:0014889]; positive regulation of cold-induced thermogenesis [GO:0120162]		extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	scyllo-inosamine-4-phosphate amidinotransferase activity [GO:0015069]	amidinotransferase activity [GO:0015067]; glycine amidinotransferase activity [GO:0015068]
d1bwfo2_d2hf3a2__1		Metazoa	Proteobacteria	Arthropoda	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	cytosol [GO:0005829]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]
d1bwfy2_d3mn7a2__1		Metazoa	Proteobacteria	Arthropoda	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; microtubule binding [GO:0008017]; actin cytoskeleton organization [GO:0030036]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; actin filament-based process [GO:0030029]; actin nucleation [GO:0045010]; chorion-containing eggshell formation [GO:0007304]; oocyte karyosome formation [GO:0030717]; oogenesis [GO:0048477]; pole plasm assembly [GO:0007315]; pole plasm oskar mRNA localization [GO:0045451]; pole plasm RNA localization [GO:0007316]; protein transport [GO:0015031]; regulation of cytoskeleton organization [GO:0051493]; vesicle-mediated transport [GO:0016192]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	actin cytoskeleton organization [GO:0030036]; actin filament-based process [GO:0030029]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; actin nucleation [GO:0045010]; chorion-containing eggshell formation [GO:0007304]; oocyte karyosome formation [GO:0030717]; oogenesis [GO:0048477]; pole plasm assembly [GO:0007315]; pole plasm oskar mRNA localization [GO:0045451]; pole plasm RNA localization [GO:0007316]; protein transport [GO:0015031]; regulation of cytoskeleton organization [GO:0051493]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; microtubule binding [GO:0008017]
d1bwha__d1l20a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1bwma1_d4at6p1__1	Metazoa		Chordata									
d1bwoa__d1t12a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid binding [GO:0008289]; defense response [GO:0006952]; lipid transport [GO:0006869]; response to biotic stimulus [GO:0009607]	lipid transport [GO:0006869]	defense response [GO:0006952]; lipid transport [GO:0006869]; response to biotic stimulus [GO:0009607]			lipid binding [GO:0008289]	lipid binding [GO:0008289]
d1bwoa__d2n81a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid transport [GO:0006869]	lipid transport [GO:0006869]			lipid binding [GO:0008289]	lipid binding [GO:0008289]
d1bwpa__d4oaob___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; 1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; identical protein binding [GO:0042802]; platelet-activating factor acetyltransferase activity [GO:0047179]; brain development [GO:0007420]; lipid catabolic process [GO:0016042]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; xylan catabolic process [GO:0045493]	brain development [GO:0007420]; lipid catabolic process [GO:0016042]; spermatogenesis [GO:0007283]	xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; identical protein binding [GO:0042802]; platelet-activating factor acetyltransferase activity [GO:0047179]	acetylxylan esterase activity [GO:0046555]
d1bwra__d5tica1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; 1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; identical protein binding [GO:0042802]; platelet-activating factor acetyltransferase activity [GO:0047179]; brain development [GO:0007420]; lipid catabolic process [GO:0016042]; spermatogenesis [GO:0007283]	outer membrane-bounded periplasmic space [GO:0030288]; acyl-CoA hydrolase activity [GO:0047617]; arylesterase activity [GO:0004064]; identical protein binding [GO:0042802]; lysophospholipase activity [GO:0004622]; myristoyl-[acyl-carrier-protein] hydrolase activity [GO:0016295]; myristoyl-CoA hydrolase activity [GO:0102991]; oleoyl-[acyl-carrier-protein] hydrolase activity [GO:0004320]; palmitoyl-[acyl-carrier-protein] hydrolase activity [GO:0016296]; palmitoyl-CoA hydrolase activity [GO:0016290]; peptidase activity [GO:0008233]; phospholipase activity [GO:0004620]; lipid metabolic process [GO:0006629]	brain development [GO:0007420]; lipid catabolic process [GO:0016042]; spermatogenesis [GO:0007283]	lipid metabolic process [GO:0006629]	cytoplasm [GO:0005737]	outer membrane-bounded periplasmic space [GO:0030288]	1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; identical protein binding [GO:0042802]; platelet-activating factor acetyltransferase activity [GO:0047179]	acyl-CoA hydrolase activity [GO:0047617]; arylesterase activity [GO:0004064]; identical protein binding [GO:0042802]; lysophospholipase activity [GO:0004622]; myristoyl-[acyl-carrier-protein] hydrolase activity [GO:0016295]; myristoyl-CoA hydrolase activity [GO:0102991]; oleoyl-[acyl-carrier-protein] hydrolase activity [GO:0004320]; palmitoyl-[acyl-carrier-protein] hydrolase activity [GO:0016296]; palmitoyl-CoA hydrolase activity [GO:0016290]; peptidase activity [GO:0008233]; phospholipase activity [GO:0004620]
d1bwsa__d4zrna___1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; GDP-L-fucose synthase activity [GO:0050577]; isomerase activity [GO:0016853]; NADP+ binding [GO:0070401]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; colanic acid biosynthetic process [GO:0009242]	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; colanic acid biosynthetic process [GO:0009242]		cytoplasm [GO:0005737]		GDP-L-fucose synthase activity [GO:0050577]; isomerase activity [GO:0016853]; NADP+ binding [GO:0070401]	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]
d1bwvc2_d3kdng1__1			Rhodophyta	Euryarchaeota	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]		AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]			magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1bwve2_d3kdoc1__1			Rhodophyta	Euryarchaeota	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]		AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]			magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1bwvw__d2vdhk___1		Viridiplantae	Rhodophyta	Chlorophyta	chloroplast [GO:0009507]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]		magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1bwvy__d1iwaj___1			Rhodophyta	Rhodophyta	chloroplast [GO:0009507]	chloroplast [GO:0009507]			chloroplast [GO:0009507]	chloroplast [GO:0009507]		
d1bwwb__d1tmcb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1bwza1_d3ejxe2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]	diaminopimelate epimerase activity [GO:0008837]	diaminopimelate epimerase activity [GO:0008837]
d1bwza2_d5ha4b1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	diaminopimelate epimerase activity [GO:0008837]	diaminopimelate epimerase activity [GO:0008837]
d1bx0a1_d1go2a1__1	Viridiplantae		Streptophyta	Cyanobacteria	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d1bx0a1_d5vwaa1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	photosynthesis [GO:0015979]		chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	chloroplast [GO:0009507]	ferredoxin-NADP+ reductase activity [GO:0004324]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1bx1a2_d5h5ja2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	photosynthesis [GO:0015979]		chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	chloroplast [GO:0009507]	ferredoxin-NADP+ reductase activity [GO:0004324]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1bx2b1_d5hysb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1bx2b2_d3o4la1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1bx2b2_d4pjcc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1bx2e1_d3u30b1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1bxba__d4a8la___1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1bxba__d5nh6d___1		Fungi	Deinococcus-Thermus	Chytridiomycota	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d1bxbb__d3kcja___1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1bxbc__d4xkmh___1			Deinococcus-Thermus	Bacteroidetes	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1bxhc__d1x50a1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]		cell adhesion [GO:0007155]		collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d1bxhc__d2dvdd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1bxnl__d1uppl___1		Viridiplantae	Proteobacteria	Streptophyta	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1bxqa__d5oywa___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]			extracellular region [GO:0005576]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1bxra2_d2b1gc1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1bxra4_d2yzma1__1			Proteobacteria	Deinococcus-Thermus	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1bxra4_d3rv3a1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1bxra6_d1jllb2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d1bxrc3_d1cs0c4__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1bxrd2_d1gpma2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; GMP synthase activity [GO:0003921]; identical protein binding [GO:0042802]; pyrophosphatase activity [GO:0016462]; glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; GMP synthase activity [GO:0003921]; identical protein binding [GO:0042802]; pyrophosphatase activity [GO:0016462]
d1bxrd2_d4bflb2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1bxre2_d1ik4c___1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	methylglyoxal synthase activity [GO:0008929]
d1bxre3_d2zdqa1__1			Proteobacteria	Deinococcus-Thermus	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1bxre4_d2w70a1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1bxre5_d2r87c2__1			Proteobacteria	Euryarchaeota	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]
d1bxre6_d1eudb2__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]
d1bxre6_d2v5aa2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1bxrg2_d1s8ab___1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	methylglyoxal synthase activity [GO:0008929]
d1bxrg3_d2w6qa1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1bxrg4_d4mv8a1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1bxsa__d3ifhs1__1	Metazoa		Chordata		cytosol [GO:0005829]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]	
d1bxsc__d2onml___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d1bxsd__d1o04c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d1bxva__d1gw0b2__1		Fungi	Cyanobacteria	Ascomycota	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	thylakoid membrane [GO:0042651]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1bxzb2_d1o8cb4__1			Firmicutes	Proteobacteria	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; acryloyl-CoA reductase (NADP+) activity [GO:0043957]				cytoplasm [GO:0005737]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	acryloyl-CoA reductase (NADP+) activity [GO:0043957]
d1by1a1_d1lb1g1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein kinase binding [GO:0019901]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; G protein-coupled receptor signaling pathway [GO:0007186]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cell cortex [GO:0005938]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	guanyl-nucleotide exchange factor activity [GO:0005085]; protein kinase binding [GO:0019901]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d1byca__d3edka2__1	Viridiplantae		Streptophyta	Bacteroidetes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d1byea1_d2on5d2__1	Viridiplantae	Metazoa	Streptophyta	Nematoda (roundworms)	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	transferase activity [GO:0016740]	glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]		cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]		glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d1byea2_d2gt6a1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; copper ion binding [GO:0005507]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]	copper ion binding [GO:0005507]
d1byeb2_d2vlta___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	cell [GO:0005623]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]	protein disulfide oxidoreductase activity [GO:0015035]
d1byec1_d2pmtd1__1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]		cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1byec2_d2fchd___1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1byec2_d5a5kq1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d1byfa__d1rdo1___1	Metazoa	Metazoa	Chordata	Chordata	carbohydrate binding [GO:0030246]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]		complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]		collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]
d1byfb__d4wcoa___1	Metazoa	Metazoa	Chordata	Chordata	carbohydrate binding [GO:0030246]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; regulation of immune response [GO:0050776]		cell surface receptor signaling pathway [GO:0007166]; regulation of immune response [GO:0050776]		cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]
d1byha__d1gnza___1		Viridiplantae	Firmicutes	Streptophyta	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]				licheninase activity [GO:0042972]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1byia__d3wxma1__1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; ATP binding [GO:0005524]; dethiobiotin synthase activity [GO:0004141]; magnesium ion binding [GO:0000287]; biotin biosynthetic process [GO:0009102]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	biotin biosynthetic process [GO:0009102]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; dethiobiotin synthase activity [GO:0004141]; magnesium ion binding [GO:0000287]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1byma__d1u8rd3__1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein dimerization activity [GO:0046983]; SH3 domain binding [GO:0017124]; transition metal ion binding [GO:0046914]; protein homooligomerization [GO:0051260]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]	protein homooligomerization [GO:0051260]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein dimerization activity [GO:0046983]; SH3 domain binding [GO:0017124]; transition metal ion binding [GO:0046914]	cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]
d1byna__d2ncea___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; central nervous system neuron axonogenesis [GO:0021955]; establishment of protein localization [GO:0045184]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of heart contraction [GO:0045822]; negative regulation of translation [GO:0017148]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of dense core granule biogenesis [GO:2000707]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of platelet aggregation [GO:0090330]; regulation of receptor-mediated endocytosis [GO:0048259]; response to antibiotic [GO:0046677]; response to corticosterone [GO:0051412]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; central nervous system neuron axonogenesis [GO:0021955]; establishment of protein localization [GO:0045184]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of heart contraction [GO:0045822]; negative regulation of translation [GO:0017148]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of dense core granule biogenesis [GO:2000707]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of platelet aggregation [GO:0090330]; regulation of receptor-mediated endocytosis [GO:0048259]; response to antibiotic [GO:0046677]; response to corticosterone [GO:0051412]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]	ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270]
d1byoa__d2iwej___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane [GO:0009535]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1bypa__d3zdwa3__1	Viridiplantae		Streptophyta	Firmicutes	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]	chloroplast thylakoid membrane [GO:0009535]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1byta2_d4wfoa2__1		Viridiplantae		Streptophyta		cytoplasm [GO:0005737]; linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]; oxylipin biosynthetic process [GO:0031408]		oxylipin biosynthetic process [GO:0031408]		cytoplasm [GO:0005737]		linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]
d1byua__d3iija1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; melanosome [GO:0042470]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RISC complex [GO:0016442]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; nuclear export signal receptor activity [GO:0005049]; pre-miRNA binding [GO:0070883]; RISC complex binding [GO:1905172]; cell division [GO:0051301]; GTP metabolic process [GO:0046039]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of protein export from nucleus [GO:0046827]; pre-miRNA export from nucleus [GO:0035281]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]	Cajal body [GO:0015030]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; nucleoside monophosphate kinase activity [GO:0050145]; nucleobase-containing small molecule interconversion [GO:0015949]	cell division [GO:0051301]; GTP metabolic process [GO:0046039]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of protein export from nucleus [GO:0046827]; pre-miRNA export from nucleus [GO:0035281]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]	nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; melanosome [GO:0042470]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RISC complex [GO:0016442]	Cajal body [GO:0015030]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; nuclear export signal receptor activity [GO:0005049]; pre-miRNA binding [GO:0070883]; RISC complex binding [GO:1905172]	adenylate kinase activity [GO:0004017]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; nucleoside monophosphate kinase activity [GO:0050145]
d1bywa__d4eepa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; inward rectifier potassium channel complex [GO:1902937]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]; C3HC4-type RING finger domain binding [GO:0055131]; delayed rectifier potassium channel activity [GO:0005251]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]; voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1902282]; cardiac conduction [GO:0061337]; cardiac muscle contraction [GO:0060048]; cellular response to drug [GO:0035690]; membrane depolarization during action potential [GO:0086010]; membrane repolarization [GO:0086009]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; membrane repolarization during ventricular cardiac muscle cell action potential [GO:0098915]; negative regulation of potassium ion export across plasma membrane [GO:1903765]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion export across plasma membrane [GO:0097623]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of heart rate by hormone [GO:0003064]; regulation of membrane potential [GO:0042391]; regulation of membrane repolarization [GO:0060306]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; ventricular cardiac muscle cell action potential [GO:0086005]	cell [GO:0005623]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plastid [GO:0009536]; ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein serine/threonine kinase activity [GO:0004674]; chloroplast relocation [GO:0009902]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-chromophore linkage [GO:0018298]; response to blue light [GO:0009637]; stomatal movement [GO:0010118]	cardiac conduction [GO:0061337]; cardiac muscle contraction [GO:0060048]; cellular response to drug [GO:0035690]; membrane depolarization during action potential [GO:0086010]; membrane repolarization [GO:0086009]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; membrane repolarization during ventricular cardiac muscle cell action potential [GO:0098915]; negative regulation of potassium ion export across plasma membrane [GO:1903765]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion export across plasma membrane [GO:0097623]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of heart rate by hormone [GO:0003064]; regulation of membrane potential [GO:0042391]; regulation of membrane repolarization [GO:0060306]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; ventricular cardiac muscle cell action potential [GO:0086005]	chloroplast relocation [GO:0009902]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; protein phosphorylation [GO:0006468]; response to blue light [GO:0009637]; stomatal movement [GO:0010118]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; inward rectifier potassium channel complex [GO:1902937]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]	cell [GO:0005623]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plastid [GO:0009536]	C3HC4-type RING finger domain binding [GO:0055131]; delayed rectifier potassium channel activity [GO:0005251]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]; voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1902282]	ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein serine/threonine kinase activity [GO:0004674]
d1bz0b__d2auob___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1bz1a__d2bv8c___1	Metazoa		Chordata	Rhodophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1bz1a__d2gtlg1__1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	metal ion binding [GO:0046872]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	metal ion binding [GO:0046872]
d1bz1b__d1uc3k___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1bz7b1_d3wihm2__1		Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]
d1bz7b2_d2gjzl2__1		Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d1bz9a2_d4l3cg1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1bz9b2_d4yk4y2__1	Metazoa		Chordata	Negarnaviricota	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]
d1bzca__d3lj8a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; activation of MAPK activity [GO:0000187]; inactivation of MAPK activity [GO:0000188]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; protein dephosphorylation [GO:0006470]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	activation of MAPK activity [GO:0000187]; inactivation of MAPK activity [GO:0000188]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; protein dephosphorylation [GO:0006470]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1bzca__d4hjqa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	alpha-beta T cell receptor complex [GO:0042105]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cell adhesion molecule binding [GO:0050839]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; abortive mitotic cell cycle [GO:0033277]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein dephosphorylation [GO:0006470]; regulation of B cell differentiation [GO:0045577]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	abortive mitotic cell cycle [GO:0033277]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein dephosphorylation [GO:0006470]; regulation of B cell differentiation [GO:0045577]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	alpha-beta T cell receptor complex [GO:0042105]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	cell adhesion molecule binding [GO:0050839]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d1bzda__d3ng5a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1bzea__d3iwvd___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1bzha__d5gnha2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]; identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1bzpa__d1y22c___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1bzqk__d1l2gd___1	Metazoa		Chordata		extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; metal ion binding [GO:0046872]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]		entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	extracellular region [GO:0005576]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	metal ion binding [GO:0046872]
d1bzwb__d1s0da1__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1bzwd__d2celb___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d1bzxe__d2z3ca___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1bzyb__d5t3ob1__1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; adenine salvage [GO:0006168]; central nervous system neuron development [GO:0021954]; cerebral cortex neuron differentiation [GO:0021895]; dendrite morphogenesis [GO:0048813]; dopamine metabolic process [GO:0042417]; GMP catabolic process [GO:0046038]; GMP salvage [GO:0032263]; grooming behavior [GO:0007625]; guanine salvage [GO:0006178]; hypoxanthine metabolic process [GO:0046100]; hypoxanthine salvage [GO:0043103]; IMP metabolic process [GO:0046040]; IMP salvage [GO:0032264]; locomotory behavior [GO:0007626]; lymphocyte proliferation [GO:0046651]; positive regulation of dopamine metabolic process [GO:0045964]; protein homotetramerization [GO:0051289]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside salvage [GO:0006166]; purine-containing compound salvage [GO:0043101]; response to amphetamine [GO:0001975]; striatum development [GO:0021756]; T cell mediated cytotoxicity [GO:0001913]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	adenine salvage [GO:0006168]; central nervous system neuron development [GO:0021954]; cerebral cortex neuron differentiation [GO:0021895]; dendrite morphogenesis [GO:0048813]; dopamine metabolic process [GO:0042417]; GMP catabolic process [GO:0046038]; GMP salvage [GO:0032263]; grooming behavior [GO:0007625]; guanine salvage [GO:0006178]; hypoxanthine metabolic process [GO:0046100]; hypoxanthine salvage [GO:0043103]; IMP metabolic process [GO:0046040]; IMP salvage [GO:0032264]; locomotory behavior [GO:0007626]; lymphocyte proliferation [GO:0046651]; positive regulation of dopamine metabolic process [GO:0045964]; protein homotetramerization [GO:0051289]; purine-containing compound salvage [GO:0043101]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside salvage [GO:0006166]; response to amphetamine [GO:0001975]; striatum development [GO:0021756]; T cell mediated cytotoxicity [GO:0001913]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]
d1bzzc__d1yena___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1c08b__d5i1el2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1c08c__d1l91a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1c0aa2_d1l0wa2__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	aspartyl-tRNA aminoacylation [GO:0006422]	aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]
d1c0eb__d4etma1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]			cytoplasm [GO:0005737]		acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d1c0ga2_d3bf3e2__1	Metazoa		Chordata	Thermotogae	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	coenzyme A biosynthetic process [GO:0015937]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d1c0hb__d1gh0s___1				Cyanobacteria		phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]		
d1c0hb__d3gqrd___1		Metazoa		Chordata		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1c0ia2_d1f8rb2__1	Fungi	Metazoa	Basidiomycota	Chordata	peroxisome [GO:0005777]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; D-amino acid metabolic process [GO:0046416]	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	D-amino acid metabolic process [GO:0046416]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	peroxisome [GO:0005777]	extracellular region [GO:0005576]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]
d1c0na__d1ibja___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]; selenocysteine lyase activity [GO:0009000]; cysteine metabolic process [GO:0006534]; iron-sulfur cluster assembly [GO:0016226]; selenium compound metabolic process [GO:0001887]; sulfur compound metabolic process [GO:0006790]; sulfur incorporation into metallo-sulfur cluster [GO:0031162]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; carbon-sulfur lyase activity [GO:0016846]; cystathionine beta-lyase activity [GO:0004121]; cystathionine gamma-lyase activity [GO:0004123]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process via cystathionine [GO:0019343]; L-methionine biosynthetic process from L-homoserine via cystathionine [GO:0019279]; transsulfuration [GO:0019346]	cysteine metabolic process [GO:0006534]; iron-sulfur cluster assembly [GO:0016226]; selenium compound metabolic process [GO:0001887]; sulfur compound metabolic process [GO:0006790]; sulfur incorporation into metallo-sulfur cluster [GO:0031162]	cysteine biosynthetic process via cystathionine [GO:0019343]; L-methionine biosynthetic process from L-homoserine via cystathionine [GO:0019279]; transsulfuration [GO:0019346]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]; selenocysteine lyase activity [GO:0009000]	carbon-sulfur lyase activity [GO:0016846]; cystathionine beta-lyase activity [GO:0004121]; cystathionine gamma-lyase activity [GO:0004123]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; pyridoxal phosphate binding [GO:0030170]
d1c0pa2_d2xfqb2__1	Fungi	Metazoa	Basidiomycota	Chordata	peroxisome [GO:0005777]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; D-amino acid metabolic process [GO:0046416]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-amino acid metabolic process [GO:0046416]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	peroxisome [GO:0005777]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1c12b2_d5nbwa2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1c14b__d1kbza___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; dTDP-4-dehydrorhamnose reductase activity [GO:0008831]; metal ion binding [GO:0046872]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	dTDP-4-dehydrorhamnose reductase activity [GO:0008831]; metal ion binding [GO:0046872]
d1c15a__d3ygsc___1	Metazoa	Metazoa	Chordata	Chordata	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d1c16e1_d5mhrq1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1c1ca1_d4fjka1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1c1eh1_d4l3ci2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1c1eh2_d3if1a1__1												
d1c1el1_d3tvmd1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1c1fa__d5gm5e___1	Metazoa	Fungi	Chordata	Ascomycota	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]	cellulase activity [GO:0008810]
d1c1ha__d2xvxa___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]	periplasmic space [GO:0042597]; cobalt ion binding [GO:0050897]; heme binding [GO:0020037]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; sirohydrochlorin ferrochelatase activity [GO:0051266]; anaerobic cobalamin biosynthetic process [GO:0019251]; protein tetramerization [GO:0051262]	heme biosynthetic process [GO:0006783]	anaerobic cobalamin biosynthetic process [GO:0019251]; protein tetramerization [GO:0051262]	cytoplasm [GO:0005737]	periplasmic space [GO:0042597]	ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]	cobalt ion binding [GO:0050897]; heme binding [GO:0020037]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; sirohydrochlorin ferrochelatase activity [GO:0051266]
d1c1jb__d1fxfb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]; bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	extracellular region [GO:0005576]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]
d1c1jc__d3mlmb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]
d1c1la__d1hv0a___1	Metazoa		Chordata	Firmicutes	carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]
d1c1ma__d3urca___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1c1pa__d1sqaa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d1c1pa__d3h7ta___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1c1ra__d2bdic___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1c1xa2_d1gz3a2__1		Metazoa	Actinobacteria	Chordata	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]; malate metabolic process [GO:0006108]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031]; tricarboxylic acid cycle [GO:0006099]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	malate metabolic process [GO:0006108]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031]; tricarboxylic acid cycle [GO:0006099]		intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]	electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]
d1c1yb__d4zria1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; mitogen-activated protein kinase kinase binding [GO:0031434]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; activation of adenylate cyclase activity [GO:0007190]; activation of MAPKK activity [GO:0000186]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; death-inducing signaling complex assembly [GO:0071550]; face development [GO:0060324]; heart development [GO:0007507]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; intermediate filament cytoskeleton organization [GO:0045104]; ion transmembrane transport [GO:0034220]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of protein complex assembly [GO:0031333]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet activation [GO:0030168]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell differentiation [GO:0045595]; regulation of cell motility [GO:2000145]; regulation of Rho protein signal transduction [GO:0035023]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; wound healing [GO:0042060]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	activation of adenylate cyclase activity [GO:0007190]; activation of MAPKK activity [GO:0000186]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; death-inducing signaling complex assembly [GO:0071550]; face development [GO:0060324]; heart development [GO:0007507]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; intermediate filament cytoskeleton organization [GO:0045104]; ion transmembrane transport [GO:0034220]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of protein complex assembly [GO:0031333]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet activation [GO:0030168]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell differentiation [GO:0045595]; regulation of cell motility [GO:2000145]; regulation of Rho protein signal transduction [GO:0035023]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; wound healing [GO:0042060]	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; mitogen-activated protein kinase kinase binding [GO:0031434]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	actin binding [GO:0003779]
d1c20a__d2jrza1__1	Metazoa	Metazoa	Arthropoda	Chordata	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; repressing transcription factor binding [GO:0070491]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; anterior/posterior pattern specification [GO:0009952]; axon guidance [GO:0007411]; dendrite morphogenesis [GO:0048813]; embryonic pattern specification [GO:0009880]; gliogenesis [GO:0042063]; male courtship behavior [GO:0008049]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oogenesis [GO:0048477]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of female receptivity [GO:0045924]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]	cytosol [GO:0005829]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K4 specific) [GO:0032453]; histone demethylase activity (H3-trimethyl-K4 specific) [GO:0034647]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription, DNA-templated [GO:0045892]; rhythmic process [GO:0048511]	anterior/posterior pattern specification [GO:0009952]; axon guidance [GO:0007411]; dendrite morphogenesis [GO:0048813]; embryonic pattern specification [GO:0009880]; gliogenesis [GO:0042063]; male courtship behavior [GO:0008049]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oogenesis [GO:0048477]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of female receptivity [GO:0045924]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]	chromatin remodeling [GO:0006338]; histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription, DNA-templated [GO:0045892]; rhythmic process [GO:0048511]	nucleus [GO:0005634]	cytosol [GO:0005829]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; repressing transcription factor binding [GO:0070491]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K4 specific) [GO:0032453]; histone demethylase activity (H3-trimethyl-K4 specific) [GO:0034647]; zinc ion binding [GO:0008270]
d1c24a__d3mx6a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]
d1c29b__d2clkb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	tryptophan biosynthetic process [GO:0000162]	tryptophan biosynthetic process [GO:0000162]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]
d1c29b__d2pqmb___1			Proteobacteria		cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	cysteine synthase activity [GO:0004124]; cysteine biosynthetic process from serine [GO:0006535]	tryptophan biosynthetic process [GO:0000162]	cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	cysteine synthase activity [GO:0004124]
d1c2ba__d5ehxa___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]; acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]	acetylcholinesterase activity [GO:0003990]
d1c2ka__d1qrxa___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d1c2ob__d3g0gc2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]; acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1c2od__d4xvce1__1	Metazoa		Chordata		anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]; acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]		acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]		anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]		acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]	
d1c2yf__d1ejbd___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1c2yg__d1rvvo___1	Viridiplantae		Streptophyta	Firmicutes	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1c2yj__d4kq6g___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	mitochondrial intermembrane space [GO:0005758]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]	mitochondrial intermembrane space [GO:0005758]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1c2ys__d2jfbb___1	Viridiplantae		Streptophyta		chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]		chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]		6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	
d1c30a2_d1s8ae___1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	methylglyoxal synthase activity [GO:0008929]
d1c30a3_d1c30e4__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1c30a4_d5bpfb1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1c30a5_d4fu0a2__1			Proteobacteria	Firmicutes	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1c30b2_d2lxna___1			Proteobacteria	Euryarchaeota	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; GMP synthase activity [GO:0003921]; glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; GMP synthase activity [GO:0003921]
d1c30d2_d3p9qb2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1c30e3_d1c3oe4__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1c30f2_d1cf9d1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1c30g4_d4tv9f1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1c3aa__d3paka2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]		cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	extracellular region [GO:0005576]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]
d1c3da1_d1d8eb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1c3hb__d1oqdj___1	Metazoa	Metazoa	Chordata	Chordata	cell periphery [GO:0071944]; cell surface [GO:0009986]; collagen trimer [GO:0005581]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; sialic acid binding [GO:0033691]; signaling receptor binding [GO:0005102]; brown fat cell differentiation [GO:0050873]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; circadian rhythm [GO:0007623]; detection of oxidative stress [GO:0070994]; fatty acid beta-oxidation [GO:0006635]; fatty acid oxidation [GO:0019395]; gene expression [GO:0010467]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell migration [GO:0030336]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hormone secretion [GO:0046888]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intracellular protein transport [GO:0090317]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metanephric mesenchymal cell migration [GO:2000590]; negative regulation of phagocytosis [GO:0050765]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000584]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of receptor binding [GO:1900121]; negative regulation of synaptic transmission [GO:0050805]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of fatty acid metabolic process [GO:0045923]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen (starch) synthase activity [GO:2000467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of metanephric glomerular visceral epithelial cell development [GO:2000478]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myeloid cell apoptotic process [GO:0033034]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of renal albumin absorption [GO:2000534]; positive regulation of signal transduction [GO:0009967]; protein homooligomerization [GO:0051260]; protein localization to plasma membrane [GO:0072659]; regulation of glucose metabolic process [GO:0010906]; response to activity [GO:0014823]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to linoleic acid [GO:0070543]; response to nutrient [GO:0007584]; response to sucrose [GO:0009744]; response to tumor necrosis factor [GO:0034612]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	brown fat cell differentiation [GO:0050873]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; circadian rhythm [GO:0007623]; detection of oxidative stress [GO:0070994]; fatty acid beta-oxidation [GO:0006635]; fatty acid oxidation [GO:0019395]; gene expression [GO:0010467]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell migration [GO:0030336]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hormone secretion [GO:0046888]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intracellular protein transport [GO:0090317]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metanephric mesenchymal cell migration [GO:2000590]; negative regulation of phagocytosis [GO:0050765]; negative regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000584]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of receptor binding [GO:1900121]; negative regulation of synaptic transmission [GO:0050805]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of fatty acid metabolic process [GO:0045923]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen (starch) synthase activity [GO:2000467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of metanephric glomerular visceral epithelial cell development [GO:2000478]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myeloid cell apoptotic process [GO:0033034]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of renal albumin absorption [GO:2000534]; positive regulation of signal transduction [GO:0009967]; protein homooligomerization [GO:0051260]; protein localization to plasma membrane [GO:0072659]; regulation of glucose metabolic process [GO:0010906]; response to activity [GO:0014823]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to linoleic acid [GO:0070543]; response to nutrient [GO:0007584]; response to sucrose [GO:0009744]; response to tumor necrosis factor [GO:0034612]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell periphery [GO:0071944]; cell surface [GO:0009986]; collagen trimer [GO:0005581]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; sialic acid binding [GO:0033691]; signaling receptor binding [GO:0005102]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]
d1c3ia__d5i4ob___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1c3ib__d5dpfe___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1c3na__d2bn0b___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d1c3ob2_d3pq5a2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1c3oc2_d1thzb1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1c3oc3_d4mv7a1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1c3oc4_d3lp8a1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d1c3oc5_d2p0ab2__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; ATP binding [GO:0005524]; neurotransmitter secretion [GO:0007269]; regulation of synaptic transmission, GABAergic [GO:0032228]; synaptic vesicle clustering [GO:0097091]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	neurotransmitter secretion [GO:0007269]; regulation of synaptic transmission, GABAergic [GO:0032228]; synaptic vesicle clustering [GO:0097091]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]
d1c3od2_d1kxjb1__1			Proteobacteria	Thermotogae	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; glutaminase activity [GO:0004359]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; glutamine metabolic process [GO:0006541]; histidine biosynthetic process [GO:0000105]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	glutamine metabolic process [GO:0006541]; histidine biosynthetic process [GO:0000105]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	glutaminase activity [GO:0004359]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]
d1c3od2_d3pq5d2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1c3oe2_d2xw6c___1			Proteobacteria	Deinococcus-Thermus	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	methylglyoxal synthase activity [GO:0008929]
d1c3oe3_d1ce8g3__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1c3oe4_d2r86a1__1			Proteobacteria	Euryarchaeota	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]
d1c3oe5_d3ethb3__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]
d1c3og3_d1a9xc4__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1c3og3_d4tuyf1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1c3og4_d1e4ea1__1			Proteobacteria	Firmicutes	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1c3og4_d1kjqa2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d1c3oh2_d5sy4b___1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; hydrolase activity [GO:0016787]; protein deglycase activity [GO:0036524]; cellular response to oxidative stress [GO:0034599]; DNA repair [GO:0006281]; guanine deglycation, glyoxal removal [GO:0106046]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycosylation [GO:0006517]; protein refolding [GO:0042026]; protein repair [GO:0030091]; response to heat [GO:0009408]; ribosome biogenesis [GO:0042254]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cellular response to oxidative stress [GO:0034599]; DNA repair [GO:0006281]; guanine deglycation, glyoxal removal [GO:0106046]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycosylation [GO:0006517]; protein refolding [GO:0042026]; protein repair [GO:0030091]; response to heat [GO:0009408]; ribosome biogenesis [GO:0042254]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	hydrolase activity [GO:0016787]; protein deglycase activity [GO:0036524]
d1c3qc1_d1esjb1__1			Firmicutes	Firmicutes	ATP binding [GO:0005524]; hydroxyethylthiazole kinase activity [GO:0004417]; magnesium ion binding [GO:0000287]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	ATP binding [GO:0005524]; hydroxyethylthiazole kinase activity [GO:0004417]; magnesium ion binding [GO:0000287]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]			ATP binding [GO:0005524]; hydroxyethylthiazole kinase activity [GO:0004417]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; hydroxyethylthiazole kinase activity [GO:0004417]; magnesium ion binding [GO:0000287]
d1c3ya__d3ogna___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d1c3za__d3caba___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d1c44a__d5aija2__1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; peroxisome [GO:0005777]; lipid binding [GO:0008289]; propanoyl-CoA C-acyltransferase activity [GO:0033814]; lipid transport [GO:0006869]	outer membrane-bounded periplasmic space [GO:0030288]; alkyl sulfatase activity [GO:0018741]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]; dodecyl sulfate metabolic process [GO:0018909]	lipid transport [GO:0006869]	dodecyl sulfate metabolic process [GO:0018909]	mitochondrion [GO:0005739]; peroxisome [GO:0005777]	outer membrane-bounded periplasmic space [GO:0030288]	lipid binding [GO:0008289]; propanoyl-CoA C-acyltransferase activity [GO:0033814]	alkyl sulfatase activity [GO:0018741]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]
d1c45a__d1lyea___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1c47a1_d5jn5b3__1	Metazoa	Metazoa	Chordata	Chordata	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	glucose metabolic process [GO:0006006]	galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	sarcoplasmic reticulum [GO:0016529]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1c47a2_d1pcmx2__1	Metazoa		Chordata	Proteobacteria	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	glucose metabolic process [GO:0006006]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	sarcoplasmic reticulum [GO:0016529]		magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]
d1c47a3_d4il8a2__1	Metazoa		Chordata	Proteobacteria	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	glucose metabolic process [GO:0006006]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	sarcoplasmic reticulum [GO:0016529]		magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]
d1c47b3_d4mrqa2__1	Metazoa		Chordata	Proteobacteria	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	glucose metabolic process [GO:0006006]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	sarcoplasmic reticulum [GO:0016529]		magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]
d1c4aa2_d3b2gb___1			Firmicutes	Cyanobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1c4ga2_d1k2yx3__1	Metazoa		Chordata	Proteobacteria	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	glucose metabolic process [GO:0006006]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	sarcoplasmic reticulum [GO:0016529]		magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]
d1c4gb4_d1kfqa4__1	Metazoa		Chordata	Ciliophora	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	glucose metabolic process [GO:0006006]	galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	sarcoplasmic reticulum [GO:0016529]	cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1c4qb__d1czwf___1					extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1c4qe__d1qb5d___1				Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1c4ra__d5ik8b2__1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]	signaling receptor binding [GO:0005102]
d1c4rd__d5kxed___1	Metazoa	Viridiplantae	Chordata	Streptophyta	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	carbohydrate binding [GO:0030246]	angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]		axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]	carbohydrate binding [GO:0030246]
d1c4za__d2xbbb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle phase transition [GO:0044770]; cell population proliferation [GO:0008283]; cellular protein modification process [GO:0006464]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to steroid hormone stimulus [GO:0071383]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein K11-linked ubiquitination [GO:0070979]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cell cycle phase transition [GO:0044770]; cell population proliferation [GO:0008283]; cellular protein modification process [GO:0006464]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to steroid hormone stimulus [GO:0071383]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein K11-linked ubiquitination [GO:0070979]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; enzyme binding [GO:0019899]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]; ubiquitin-protein transferase activity [GO:0004842]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1c50a__d3otia1__1	Metazoa		Chordata	Actinobacteria	skeletal muscle myofibril [GO:0098723]; glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]; glycogen metabolic process [GO:0005977]	glucosyltransferase activity [GO:0046527]	glycogen metabolic process [GO:0005977]		skeletal muscle myofibril [GO:0098723]		glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]	glucosyltransferase activity [GO:0046527]
d1c52a__d2oz1e1__1			Deinococcus-Thermus	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1c57a__d5kxcc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1c5bh1_d1tvhb2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1c5ch1_d3se9l1__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1c5ch2_d3qcvl1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1c5da1_d1tvbd1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1c5da2_d1ob1b1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1c5db1_d1jn6b1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1c5dh1_d6b3sd2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d1c5fc__d3rdda___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	protein folding [GO:0006457]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1c5fe__d1ynda___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	protein folding [GO:0006457]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1c5fi__d5nowa___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	protein folding [GO:0006457]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1c5fm__d1vbsa___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	protein folding [GO:0006457]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1c5ha__d1v6ng___1		Viridiplantae	Firmicutes	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1c5ia__d3vkoa___1		Metazoa	Firmicutes	Chordata	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	xylan catabolic process [GO:0045493]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d1c5md__d3suga1__1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1c5o.1_d2gz8a___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1c5pa__d1duaa___1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]
d1c5ra__d1uk3a___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1c5ta__d2vioa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d1c5ua__d3fvfb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; sodium channel regulator activity [GO:0017080]; cornification [GO:0070268]; positive regulation of sodium ion transport [GO:0010765]	digestion [GO:0007586]; proteolysis [GO:0006508]	cornification [GO:0070268]; positive regulation of sodium ion transport [GO:0010765]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; sodium channel regulator activity [GO:0017080]
d1c64a__d4g4ca___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1c66a__d1gfra___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1c68a__d168la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1c68a__d4n1el___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1c69a__d1ctwa___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1c6aa__d1cj9a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1c6ba__d2z2eb___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]; cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]
d1c6da__d4lyza___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1c6fa__d1hnla___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1c6ha__d1cv6a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1c6ha__d5feka___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1c6ia__d2i26m___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1c6ja__d133la___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1c6la__d3cdta___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1c6ma__d1quga___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1c6ma__d4xjha___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1c6na__d4nhsa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1c6qa__d1b7pa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1c6ta__d3dn4a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1c6xa__d5p41a___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1c6xb__d5p2za___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1c6yb__d4m8yb___1					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]
d1c6yb__d4yd7a___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1c6za__d4yd6a___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1c6za__d9hvpa___1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1c6zb__d5ozia___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1c72a2_d5ecne1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1c72c2_d1w4vc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein disulfide oxidoreductase activity [GO:0015035]; protein-containing complex binding [GO:0044877]; cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein-containing complex binding [GO:0044877]; protein disulfide oxidoreductase activity [GO:0015035]
d1c72d2_d2lv3a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin-disulfide reductase activity [GO:0004791]; blastocyst formation [GO:0001825]; cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; glutathione metabolic process [GO:0006749]; spermatogenesis [GO:0007283]	glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	blastocyst formation [GO:0001825]; cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; glutathione metabolic process [GO:0006749]; spermatogenesis [GO:0007283]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin-disulfide reductase activity [GO:0004791]
d1c77a__d1ssna___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]; plasminogen activation [GO:0031639]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]; plasminogen activation [GO:0031639]	pathogenesis [GO:0009405]; plasminogen activation [GO:0031639]	pathogenesis [GO:0009405]; plasminogen activation [GO:0031639]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1c7ba__d1o1ob___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1c7bd__d3kvsa___1	Metazoa		Chordata	Rhodophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1c7db__d1babb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1c7dd__d3w4uf___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1c7eb__d2q9ub2__1			Proteobacteria		electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1c7fa__d2w5ua___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	FMN binding [GO:0010181]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]			electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	FMN binding [GO:0010181]
d1c7fb__d6nula___1			Proteobacteria	Firmicutes	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1c7ga__d4xjma___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	tyrosine metabolic process [GO:0006570]	biotin biosynthetic process [GO:0009102]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	tyrosine phenol-lyase activity [GO:0050371]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]
d1c7ja__d3wwpg1__1		Viridiplantae	Firmicutes	Streptophyta	cholinesterase activity [GO:0004104]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]					cholinesterase activity [GO:0004104]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]
d1c7ka__d2tcla___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]		cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1c7nb__d2zc0b___1			Spirochaetes	Euryarchaeota	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	alanine-glyoxylate transaminase activity [GO:0008453]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	biosynthetic process [GO:0009058]	biosynthetic process [GO:0009058]			catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	alanine-glyoxylate transaminase activity [GO:0008453]; pyridoxal phosphate binding [GO:0030170]
d1c7nc__d3ei8a1__1		Viridiplantae	Spirochaetes	Streptophyta	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	biosynthetic process [GO:0009058]	lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1c7nf__d1szka1__1			Spirochaetes	Proteobacteria	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	biosynthetic process [GO:0009058]	arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]		cytosol [GO:0005829]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]
d1c7nh__d2yhkb___1			Spirochaetes	Proteobacteria	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	biosynthetic process [GO:0009058]	tyrosine metabolic process [GO:0006570]			catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	tyrosine phenol-lyase activity [GO:0050371]
d1c7ob__d5og0a___1		Metazoa	Spirochaetes	Chordata	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]; cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]	biosynthetic process [GO:0009058]	cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]		cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]
d1c7oc__d1n8pd___1		Fungi	Spirochaetes	Ascomycota	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; carbon-sulfur lyase activity [GO:0016846]; cystathionine gamma-lyase activity [GO:0004123]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; L-cystine L-cysteine-lyase (deaminating) [GO:0044540]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process via cystathionine [GO:0019343]; transsulfuration [GO:0019346]	biosynthetic process [GO:0009058]	cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process via cystathionine [GO:0019343]; transsulfuration [GO:0019346]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	carbon-sulfur lyase activity [GO:0016846]; cystathionine gamma-lyase activity [GO:0004123]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; L-cystine L-cysteine-lyase (deaminating) [GO:0044540]; pyridoxal phosphate binding [GO:0030170]
d1c7qa__d3nbuc___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; glucose-6-phosphate isomerase activity [GO:0004347]; identical protein binding [GO:0042802]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; cellular response to oxidative stress [GO:0034599]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cellular response to oxidative stress [GO:0034599]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	glucose-6-phosphate isomerase activity [GO:0004347]	glucose-6-phosphate isomerase activity [GO:0004347]; identical protein binding [GO:0042802]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d1c7qa__d3oojg2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	glucose-6-phosphate isomerase activity [GO:0004347]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]
d1c7ta3_d1jyvc5__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	periplasmic space [GO:0042597]	beta-galactosidase complex [GO:0009341]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1c7ta3_d5broa2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	periplasmic space [GO:0042597]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d1c7ta4_d1h41a2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	glucuronoxylan catabolic process [GO:2000886]	periplasmic space [GO:0042597]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]	alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]
d1c80b__d2p2ya___1	Metazoa		Chordata	Deinococcus-Thermus	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; animal organ regeneration [GO:0031100]; carbohydrate phosphorylation [GO:0046835]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; positive regulation of glucokinase activity [GO:0033133]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]	catalytic activity [GO:0003824]	animal organ regeneration [GO:0031100]; carbohydrate phosphorylation [GO:0046835]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; positive regulation of glucokinase activity [GO:0033133]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]		6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]		6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]	catalytic activity [GO:0003824]
d1c82a3_d1f4hb4__1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	cell wall [GO:0005618]; extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1c83a__d5c16c2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein homodimerization activity [GO:0042803]; protein tyrosine phosphatase activity [GO:0004725]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein homodimerization activity [GO:0042803]; protein tyrosine phosphatase activity [GO:0004725]
d1c85a__d1ohda1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cilium assembly [GO:0060271]; DNA repair [GO:0006281]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; mitotic cell cycle arrest [GO:0071850]; positive regulation of cytokinesis [GO:0032467]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cilium assembly [GO:0060271]; DNA repair [GO:0006281]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; mitotic cell cycle arrest [GO:0071850]; positive regulation of cytokinesis [GO:0032467]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1c86a__d5ka4a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1c8aa2_d1b7ja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]	extracellular region [GO:0005576]			extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1c8ga__d3kier___1					host cell nucleus [GO:0042025]; T=1 icosahedral viral capsid [GO:0039615]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; viral penetration into host nucleus [GO:0075732]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; viral penetration into host nucleus [GO:0075732]; virion attachment to host cell [GO:0019062]		host cell nucleus [GO:0042025]; T=1 icosahedral viral capsid [GO:0039615]	viral capsid [GO:0019028]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1c8ha__d1lp3a___1					host cell nucleus [GO:0042025]; T=1 icosahedral viral capsid [GO:0039615]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; entry receptor-mediated virion attachment to host cell [GO:0098670]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; viral penetration into host nucleus [GO:0075732]	host cell nucleolus [GO:0044196]; T=1 icosahedral viral capsid [GO:0039615]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; entry receptor-mediated virion attachment to host cell [GO:0098670]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; viral penetration into host nucleus [GO:0075732]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; T=1 icosahedral viral capsid [GO:0039615]	host cell nucleolus [GO:0044196]; T=1 icosahedral viral capsid [GO:0039615]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1c8ja__d3a4za___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1c8m1__d2vq0c1__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1c8m3__d4y4yv___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1c8na__d4y4ye___1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	viral capsid [GO:0019028]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1c8nb__d2vq0b1__1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	viral capsid [GO:0019028]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1c8nc__d4y5z7___1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	viral capsid [GO:0019028]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1c8pa1_d3b83h1__1	Metazoa		Chordata		granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; signaling receptor activity [GO:0038023]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-3 [GO:0036016]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-3-mediated signaling pathway [GO:0038156]; interleukin-5-mediated signaling pathway [GO:0038043]; MAPK cascade [GO:0000165]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]		cellular protein metabolic process [GO:0044267]; cellular response to interleukin-3 [GO:0036016]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-3-mediated signaling pathway [GO:0038156]; interleukin-5-mediated signaling pathway [GO:0038043]; MAPK cascade [GO:0000165]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]		granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		cytokine receptor activity [GO:0004896]; signaling receptor activity [GO:0038023]	
d1c8qa1_d3l2la2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	extracellular space [GO:0005615]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1c8qa2_d1jz7d5__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	beta-galactosidase complex [GO:0009341]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1c8tb__d1zxvb2__1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d1c8ua2_d1c8ua1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acyl-CoA hydrolase activity [GO:0047617]; identical protein binding [GO:0042802]; acyl-CoA metabolic process [GO:0006637]; fatty acid catabolic process [GO:0009062]	cytosol [GO:0005829]; acyl-CoA hydrolase activity [GO:0047617]; identical protein binding [GO:0042802]; acyl-CoA metabolic process [GO:0006637]; fatty acid catabolic process [GO:0009062]	acyl-CoA metabolic process [GO:0006637]; fatty acid catabolic process [GO:0009062]	acyl-CoA metabolic process [GO:0006637]; fatty acid catabolic process [GO:0009062]	cytosol [GO:0005829]	cytosol [GO:0005829]	acyl-CoA hydrolase activity [GO:0047617]; identical protein binding [GO:0042802]	acyl-CoA hydrolase activity [GO:0047617]; identical protein binding [GO:0042802]
d1c8ub2_d1vi8e1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acyl-CoA hydrolase activity [GO:0047617]; identical protein binding [GO:0042802]; acyl-CoA metabolic process [GO:0006637]; fatty acid catabolic process [GO:0009062]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]; menaquinone biosynthetic process [GO:0009234]	acyl-CoA metabolic process [GO:0006637]; fatty acid catabolic process [GO:0009062]	menaquinone biosynthetic process [GO:0009234]	cytosol [GO:0005829]	cytosol [GO:0005829]	acyl-CoA hydrolase activity [GO:0047617]; identical protein binding [GO:0042802]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]
d1c8vb__d1f2db1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310]	tryptophan biosynthetic process [GO:0000162]	amine catabolic process [GO:0009310]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]
d1c8xa__d1kxha2__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d1c90a__d1ghoj5__1			Actinobacteria		extracellular region [GO:0005576]; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]	
d1c91a__d3mmuh___1			Actinobacteria	Thermotogae	extracellular region [GO:0005576]; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1c92a__d4im4a___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; acetylxylan esterase activity [GO:0046555]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; glucomannan catabolic process [GO:2000884]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]; glucomannan catabolic process [GO:2000884]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]	acetylxylan esterase activity [GO:0046555]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d1c93a__d2z1sa___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1c9bb2_d3cwud2__1	Metazoa		Chordata	Proteobacteria	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1c9be1_d1c9be2__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1c9bf2_d1qnba2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1c9bf2_d3eikb1__1	Metazoa	Fungi	Chordata	Microsporidia	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]; DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	DNA-templated transcription, initiation [GO:0006352]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]		acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]
d1c9bi1_d1c9bi2__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1c9bj2_d3eika2__1	Metazoa	Fungi	Chordata	Microsporidia	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]; DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	DNA-templated transcription, initiation [GO:0006352]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]		acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]
d1c9bq2_d1d3ub1__1	Metazoa		Chordata	Euryarchaeota	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	DNA-templated transcription, initiation [GO:0006352]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]		acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1c9bq2_d2bkzd2__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1c9ca__d5ll3b___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	isomerase activity [GO:0016853]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	isomerase activity [GO:0016853]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1c9db__d4d96c___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	D-cysteine desulfhydrase activity [GO:0019148]; D-amino acid metabolic process [GO:0046416]	tryptophan biosynthetic process [GO:0000162]	D-amino acid metabolic process [GO:0046416]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	D-cysteine desulfhydrase activity [GO:0019148]
d1c9ha__d3o5qa1__1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018]; calcium channel inhibitor activity [GO:0019855]; cyclic nucleotide binding [GO:0030551]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; signaling receptor binding [GO:0005102]; 'de novo' protein folding [GO:0006458]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; chaperone-mediated protein folding [GO:0061077]; insulin secretion [GO:0030073]; ion transmembrane transport [GO:0034220]; negative regulation of heart rate [GO:0010459]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of release of sequestered calcium ion into cytosol [GO:0051280]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neuronal action potential propagation [GO:0019227]; positive regulation of axon regeneration [GO:0048680]; positive regulation of sequestering of calcium ion [GO:0051284]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; release of sequestered calcium ion into cytosol [GO:0051209]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to redox state [GO:0051775]; response to vitamin E [GO:0033197]; smooth muscle contraction [GO:0006939]; T cell proliferation [GO:0042098]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	'de novo' protein folding [GO:0006458]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; chaperone-mediated protein folding [GO:0061077]; insulin secretion [GO:0030073]; ion transmembrane transport [GO:0034220]; negative regulation of heart rate [GO:0010459]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of release of sequestered calcium ion into cytosol [GO:0051280]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neuronal action potential propagation [GO:0019227]; positive regulation of axon regeneration [GO:0048680]; positive regulation of sequestering of calcium ion [GO:0051284]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; release of sequestered calcium ion into cytosol [GO:0051209]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to redox state [GO:0051775]; response to vitamin E [GO:0033197]; smooth muscle contraction [GO:0006939]; T cell proliferation [GO:0042098]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	calcium channel complex [GO:0034704]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	calcium channel inhibitor activity [GO:0019855]; cyclic nucleotide binding [GO:0030551]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; signaling receptor binding [GO:0005102]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1c9kb__d5ik2m2__1			Proteobacteria	Firmicutes	adenosylcobinamide kinase activity [GO:0043752]; ATP binding [GO:0005524]; cobinamide phosphate guanylyltransferase activity [GO:0008820]; GTP binding [GO:0005525]; cobalamin biosynthetic process [GO:0009236]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cobalamin biosynthetic process [GO:0009236]	ATP synthesis coupled proton transport [GO:0015986]		plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	adenosylcobinamide kinase activity [GO:0043752]; ATP binding [GO:0005524]; cobinamide phosphate guanylyltransferase activity [GO:0008820]; GTP binding [GO:0005525]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1c9sd__d3zzqe___1			Firmicutes	Firmicutes	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d1c9sn__d3zzlc___1			Firmicutes	Firmicutes	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d1c9st__d3zteh___1			Firmicutes	Firmicutes	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d1c9tb__d4x2vc___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	digestion [GO:0007586]; proteolysis [GO:0006508]	transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]
d1c9tf__d1eaua___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1c9tf__d3aw1b___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1c9ya2_d4e2fa1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; phosphate ion binding [GO:0042301]; phospholipid binding [GO:0005543]; ammonia homeostasis [GO:0097272]; anion homeostasis [GO:0055081]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; liver development [GO:0001889]; midgut development [GO:0007494]; ornithine catabolic process [GO:0006593]; protein homotrimerization [GO:0070207]; response to biotin [GO:0070781]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	ammonia homeostasis [GO:0097272]; anion homeostasis [GO:0055081]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; liver development [GO:0001889]; midgut development [GO:0007494]; ornithine catabolic process [GO:0006593]; protein homotrimerization [GO:0070207]; response to biotin [GO:0070781]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; phosphate ion binding [GO:0042301]; phospholipid binding [GO:0005543]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1ca0.1_d3gy8a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1ca1a1_d5fbba___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleic acid binding [GO:0003676]; DNA catabolic process [GO:0006308]	hemolysis in other organism [GO:0044179]	DNA catabolic process [GO:0006308]	extracellular region [GO:0005576]		phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleic acid binding [GO:0003676]
d1ca4e1_d4c9za1__1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	beta-catenin destruction complex [GO:0030877]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; anatomical structure morphogenesis [GO:0009653]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; cell cycle [GO:0007049]; cellular protein metabolic process [GO:0044267]; negative regulation of netrin-activated signaling pathway [GO:1902842]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	anatomical structure morphogenesis [GO:0009653]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; cell cycle [GO:0007049]; cellular protein metabolic process [GO:0044267]; negative regulation of netrin-activated signaling pathway [GO:1902842]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	beta-catenin destruction complex [GO:0030877]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1ca8.1_d3vgc.1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1caja__d2nwya___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1cama__d5fl6a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1caoa__d4uovd___1	Metazoa		Chordata	Aquificae	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1caqa__d2oy2f___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1cava__d4gula___1	Viridiplantae	Metazoa	Streptophyta	Chordata	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; quercetin 2,3-dioxygenase activity [GO:0008127]; transcription coregulator activity [GO:0003712]; digestion [GO:0007586]; monocyte differentiation [GO:0030224]; transcription by RNA polymerase II [GO:0006366]	protein homotrimerization [GO:0070207]	digestion [GO:0007586]; monocyte differentiation [GO:0030224]; transcription by RNA polymerase II [GO:0006366]	protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]	metal ion binding [GO:0046872]; quercetin 2,3-dioxygenase activity [GO:0008127]; transcription coregulator activity [GO:0003712]
d1cavb__d1dzta___1	Viridiplantae		Streptophyta	Proteobacteria	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	protein homotrimerization [GO:0070207]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	protein-containing complex [GO:0032991]		identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d1cavb__d2uy9a___1	Viridiplantae		Streptophyta	Firmicutes	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]; oxalate decarboxylase activity [GO:0046564]; oxalate metabolic process [GO:0033609]	protein homotrimerization [GO:0070207]	oxalate metabolic process [GO:0033609]	protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]	metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]; oxalate decarboxylase activity [GO:0046564]
d1cawa__d1fxzb2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]	endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]	protein homotrimerization [GO:0070207]		protein-containing complex [GO:0032991]	endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]	identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]	nutrient reservoir activity [GO:0045735]
d1caxd__d1ucxc2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]	endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]	protein homotrimerization [GO:0070207]		protein-containing complex [GO:0032991]	endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]	identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]	nutrient reservoir activity [GO:0045735]
d1caxe__d3qaca2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]	nutrient reservoir activity [GO:0045735]	protein homotrimerization [GO:0070207]		protein-containing complex [GO:0032991]		identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]	nutrient reservoir activity [GO:0045735]
d1caxf__d1j3qa___1	Viridiplantae		Streptophyta	Euryarchaeota	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	protein homotrimerization [GO:0070207]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]
d1caxf__d1ud1a2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]	endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]	protein homotrimerization [GO:0070207]		protein-containing complex [GO:0032991]	endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]	identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]	nutrient reservoir activity [GO:0045735]
d1cb2b__d3voia1__1	Fungi	Fungi	Ascomycota	Basidiomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1cb5a__d1m6db___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; aminopeptidase activity [GO:0004177]; carboxypeptidase activity [GO:0004180]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; identical protein binding [GO:0042802]; homocysteine catabolic process [GO:0043418]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]; response to drug [GO:0042493]; response to toxic substance [GO:0009636]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; cysteine-type endopeptidase activity [GO:0004197]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	homocysteine catabolic process [GO:0043418]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]; response to drug [GO:0042493]; response to toxic substance [GO:0009636]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	aminopeptidase activity [GO:0004177]; carboxypeptidase activity [GO:0004180]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; identical protein binding [GO:0042802]	cysteine-type endopeptidase activity [GO:0004197]
d1cb6a1_d1bp5a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d1cb6a2_d5b70a1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1cb7a__d1reqd2__1			Firmicutes	Actinobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]; anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]				cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d1cb7b__d5reqb1__1			Firmicutes	Actinobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]; anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]				cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d1cb7d__d1iwbl___1			Firmicutes	Proteobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]; anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]	propanediol dehydratase activity [GO:0050215]	anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]				cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]	propanediol dehydratase activity [GO:0050215]
d1cb8a1_d4f13a1__1			Bacteroidetes	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	periplasmic space [GO:0042597]; lyase activity [GO:0016829]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	periplasmic space [GO:0042597]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]	lyase activity [GO:0016829]
d1cb8a3_d1jz7c4__1			Bacteroidetes	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1cbia__d4zhdb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; retinoic acid catabolic process [GO:0034653]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	retinoic acid catabolic process [GO:0034653]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1cbib__d2nnqa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; retinoic acid catabolic process [GO:0034653]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	retinoic acid catabolic process [GO:0034653]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1cbjb__d3km2b___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	chloroplast [GO:0009507]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	removal of superoxide radicals [GO:0019430]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chloroplast [GO:0009507]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]
d1cblb__d5nb3e___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1cbld__d3pi3a___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1cbma__d1i7yb___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1cboa2_d1ryib2__1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]; cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cholesterol metabolic process [GO:0008203]	cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]	FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]
d1cboa2_d3cnja2__1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	cholesterol metabolic process [GO:0008203]	cholesterol metabolic process [GO:0008203]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]
d1cbra__d1u18a___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; retinoic acid catabolic process [GO:0034653]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	retinoic acid catabolic process [GO:0034653]	vasodilation [GO:0042311]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	extracellular region [GO:0005576]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]
d1cbsa__d3nadb___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	carboxy-lyase activity [GO:0016831]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	carboxy-lyase activity [GO:0016831]
d1cbsa__d4azra1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]; epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]
d1cbub__d1e79d3__1		Metazoa	Proteobacteria	Chordata	adenosylcobinamide kinase activity [GO:0043752]; ATP binding [GO:0005524]; cobinamide phosphate guanylyltransferase activity [GO:0008820]; GTP binding [GO:0005525]; cobalamin biosynthetic process [GO:0009236]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cobalamin biosynthetic process [GO:0009236]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	adenosylcobinamide kinase activity [GO:0043752]; ATP binding [GO:0005524]; cobinamide phosphate guanylyltransferase activity [GO:0008820]; GTP binding [GO:0005525]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1cbvh1_d2hmid2__1	Metazoa		Chordata		metal ion binding [GO:0046872]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1cbvl2_d2f74b2__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1cbw.1_d3d62a___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	digestion [GO:0007586]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1cbw.2_d1os8a___1	Metazoa		Chordata	Actinobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d1cbya__d1pp6a___1		Fungi	Firmicutes	Basidiomycota	extracellular region [GO:0005576]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	sporulation resulting in formation of a cellular spore [GO:0030435]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1cbzb__d4qf6i___1												
d1cbzc__d4zvwb___1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]; cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]		cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]
d1cc0a__d1s9hb1__1	Metazoa		Chordata		apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA replication [GO:0006260]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; suppression by virus of G2/M transition of host mitotic cell cycle [GO:0039592]; viral DNA genome replication [GO:0039693]; viral entry via permeabilization of inner membrane [GO:0099008]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	DNA replication [GO:0006260]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; suppression by virus of G2/M transition of host mitotic cell cycle [GO:0039592]; viral DNA genome replication [GO:0039693]; viral entry via permeabilization of inner membrane [GO:0099008]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]		GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]
d1cc2a2_d2ignd2__1		Fungi	Actinobacteria	Basidiomycota	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	cholesterol metabolic process [GO:0008203]		extracellular region [GO:0005576]		cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]
d1cc3a__d1e30a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1cc3a__d1ibzc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	metal ion binding [GO:0046872]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1cc3b__d1n70a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1cc5a__d1n50a1__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]				periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1cc6a2_d1d7la2__1			Proteobacteria	Proteobacteria	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	benzoate catabolic process via hydroxylation [GO:0043640]	benzoate catabolic process via hydroxylation [GO:0043640]			4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1ccaa__d5ksgb2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1ccba__d5kqia2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1ccca__d2oyep1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1ccga__d1oaga___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	chloroplast [GO:0009507]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1ccha__d1m70c1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1ccha__d2zbog___1			Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1ccia__d5sykb2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1ccja__d1arwa___1	Fungi	Fungi	Ascomycota	Basidiomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1ccja__d5kq2a2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1ccla__d3n8wa2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1ccwd__d6reqc1__1			Firmicutes	Actinobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]; anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]				cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d1ccza2_d1oazn___1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; signaling receptor binding [GO:0005102]; cell-cell adhesion [GO:0098609]; cellular response to interferon-gamma [GO:0071346]; cellular response to tumor necrosis factor [GO:0071356]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell-cell adhesion [GO:0098609]; cellular response to interferon-gamma [GO:0071346]; cellular response to tumor necrosis factor [GO:0071356]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	signaling receptor binding [GO:0005102]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1cd0b__d5kd4b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1cd1a2_d1s9ve2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; interferon-gamma-mediated signaling pathway [GO:0060333]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; interferon-gamma-mediated signaling pathway [GO:0060333]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d1cd1c1_d1kipa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1cd1d__d1s8db___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1cd3f__d3ng9f___1					host cell cytoplasm [GO:0030430]; viral procapsid maturation [GO:0046797]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	viral procapsid maturation [GO:0046797]		host cell cytoplasm [GO:0030430]	viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d1cd8a__d1kj2e___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]; antigen processing and presentation [GO:0019882]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; immune response [GO:0006955]; regulation of immune response [GO:0050776]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	antigen processing and presentation [GO:0019882]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; immune response [GO:0006955]; regulation of immune response [GO:0050776]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1cd9a__d5d70a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]	cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]	cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]
d1cdba__d5tz2l1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of plasma membrane [GO:0046658]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; membrane raft polarization [GO:0001766]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of T cell differentiation [GO:0045580]; T cell activation [GO:0042110]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; thrombospondin receptor activity [GO:0070053]; cell migration [GO:0016477]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; neutrophil degranulation [GO:0043312]; opsonization [GO:0008228]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of inflammatory response [GO:0050729]; positive regulation of phagocytosis [GO:0050766]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell activation [GO:0050870]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-10 production [GO:0032653]; regulation of interleukin-12 production [GO:0032655]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]; response to bacterium [GO:0009617]	apoptotic process [GO:0006915]; cell-cell adhesion [GO:0098609]; cell surface receptor signaling pathway [GO:0007166]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; membrane raft polarization [GO:0001766]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of T cell differentiation [GO:0045580]; T cell activation [GO:0042110]	cell migration [GO:0016477]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; neutrophil degranulation [GO:0043312]; opsonization [GO:0008228]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of inflammatory response [GO:0050729]; positive regulation of phagocytosis [GO:0050766]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell activation [GO:0050870]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-10 production [GO:0032653]; regulation of interleukin-12 production [GO:0032655]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]; response to bacterium [GO:0009617]	anchored component of plasma membrane [GO:0046658]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]	cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; thrombospondin receptor activity [GO:0070053]
d1cddb__d4qpda1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]	cytoplasm [GO:0005737]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydrolase activity [GO:0016787]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; embryonic viscerocranium morphogenesis [GO:0048703]; gastrulation [GO:0007369]; heart development [GO:0007507]; neural crest cell migration [GO:0001755]; neuromast deposition [GO:0048885]; one-carbon metabolic process [GO:0006730]	'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]	10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; embryonic viscerocranium morphogenesis [GO:0048703]; gastrulation [GO:0007369]; heart development [GO:0007507]; neural crest cell migration [GO:0001755]; neuromast deposition [GO:0048885]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	phosphoribosylglycinamide formyltransferase activity [GO:0004644]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydrolase activity [GO:0016787]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]
d1cdeb__d1rbza___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]	'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	phosphoribosylglycinamide formyltransferase activity [GO:0004644]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d1cdga1_d1ksra___1			Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]; actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]; actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	carbohydrate metabolic process [GO:0005975]	actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	extracellular region [GO:0005576]	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]
d1cdga2_d4jcma4__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; starch binding [GO:2001070]; transferase activity [GO:0016740]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	metal ion binding [GO:0046872]; starch binding [GO:2001070]; transferase activity [GO:0016740]
d1cdga4_d1e5nb___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]
d1cdga4_d3edfa2__1			Firmicutes	Bacteroidetes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d1cdha1_d4kkad1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1cdia1_d3tv3l1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1cdja1_d3o6fg1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1cdja2_d3vxqd1__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1cdld__d2zrse___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]
d1cdna__d1djza1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]		G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]
d1cdoa2_d3zznd1__1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	L-lactate dehydrogenase activity [GO:0004459]
d1cdpa__d1rwyb___1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cochlea development [GO:0090102]		cochlea development [GO:0090102]		cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d1cdua1_d2itdb1__1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	voltage-gated potassium channel complex [GO:0008076]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1cdua1_d4lvhf2__1	Metazoa		Chordata	Negarnaviricota	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	host cell surface receptor binding [GO:0046789]
d1cdwa2_d1mp9b2__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; male pronucleus [GO:0001940]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; transcriptional preinitiation complex [GO:0097550]; aryl hydrocarbon receptor binding [GO:0017162]; core promoter binding [GO:0001047]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; proximal promoter sequence-specific DNA binding [GO:0000987]; repressing transcription factor binding [GO:0070491]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II repressing transcription factor binding [GO:0001103]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIB-class transcription factor binding [GO:0001093]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; snRNA transcription by RNA polymerase II [GO:0042795]; spermatogenesis [GO:0007283]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; spermatogenesis [GO:0007283]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]; viral process [GO:0016032]	DNA-templated transcription, initiation [GO:0006352]	cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; male pronucleus [GO:0001940]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional preinitiation complex [GO:0097550]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]		aryl hydrocarbon receptor binding [GO:0017162]; core promoter binding [GO:0001047]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; proximal promoter sequence-specific DNA binding [GO:0000987]; repressing transcription factor binding [GO:0070491]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II repressing transcription factor binding [GO:0001103]; TFIIB-class transcription factor binding [GO:0001093]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1cdya1_d1dvfd1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1cdza__d1l0ba1__1	Metazoa	Metazoa	Chordata	Chordata	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; mitochondrial matrix [GO:0005759]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; brain development [GO:0007420]; cell cycle [GO:0007049]; chordate embryonic development [GO:0043009]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair via homologous recombination [GO:0000724]; fatty acid biosynthetic process [GO:0006633]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of histone acetylation [GO:0035067]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autoubiquitination [GO:0051865]; protein K6-linked ubiquitination [GO:0085020]; regulation of transcription by RNA polymerase II [GO:0006357]; response to estradiol [GO:0032355]; response to lipid [GO:0033993]; response to nutrient [GO:0007584]; response to organic substance [GO:0010033]	base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	brain development [GO:0007420]; cell cycle [GO:0007049]; chordate embryonic development [GO:0043009]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair via homologous recombination [GO:0000724]; fatty acid biosynthetic process [GO:0006633]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of histone acetylation [GO:0035067]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autoubiquitination [GO:0051865]; protein K6-linked ubiquitination [GO:0085020]; regulation of transcription by RNA polymerase II [GO:0006357]; response to estradiol [GO:0032355]; response to lipid [GO:0033993]; response to nutrient [GO:0007584]; response to organic substance [GO:0010033]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; mitochondrial matrix [GO:0005759]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1ce1l1_d2nx5l___1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ce6a1_d1ejol1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ce7b1_d5b2ha1__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]				carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	
d1ce7b2_d3aj6b2__1	Viridiplantae		Streptophyta		carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]
d1ce8a2_d1pl0a1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1ce8a4_d1gsoa2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d1ce8a4_d5ezyf1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1ce8a5_d1pk8a2__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	anchored component of synaptic vesicle membrane [GO:0098993]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of synaptic vesicle membrane [GO:0098850]; Golgi apparatus [GO:0005794]; intracellular organelle [GO:0043229]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; synaptonemal complex [GO:0000795]; terminal bouton [GO:0043195]; actin binding [GO:0003779]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; neuron development [GO:0048666]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle cycle [GO:0098693]; synapse organization [GO:0050808]; synaptic vesicle clustering [GO:0097091]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	neuron development [GO:0048666]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle cycle [GO:0098693]; synapse organization [GO:0050808]; synaptic vesicle clustering [GO:0097091]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	anchored component of synaptic vesicle membrane [GO:0098993]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of synaptic vesicle membrane [GO:0098850]; Golgi apparatus [GO:0005794]; intracellular organelle [GO:0043229]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; synaptonemal complex [GO:0000795]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	actin binding [GO:0003779]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]
d1ce8c3_d5d8dc1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1ce8d2_d4k2hg1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; peptidase activity [GO:0008233]; protein deglycase activity [GO:0036524]; guanine deglycation, glyoxal removal [GO:0106046]; protein deglycation, glyoxal removal [GO:0036529]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	guanine deglycation, glyoxal removal [GO:0106046]; protein deglycation, glyoxal removal [GO:0036529]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	metal ion binding [GO:0046872]; peptidase activity [GO:0008233]; protein deglycase activity [GO:0036524]
d1ce8e2_d1b93c___1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	methylglyoxal synthase activity [GO:0008929]
d1ce8e4_d2vpqb1__1			Proteobacteria	Firmicutes	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1ce8f2_d4ensb2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1ce8g3_d4egjc1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1ce8g4_d3jzib1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1ce8g5_d1cqib2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d1cela__d1q2ea___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d1cera2_d1e5la2__1		Fungi	Deinococcus-Thermus	Ascomycota	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]
d1cera2_d3cmcr2__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1cerb2_d2hjsa2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	NAD binding [GO:0051287]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; protein dimerization activity [GO:0046983]; cellular amino acid biosynthetic process [GO:0008652]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cellular amino acid biosynthetic process [GO:0008652]	cytoplasm [GO:0005737]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	NAD binding [GO:0051287]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; protein dimerization activity [GO:0046983]
d1cerr2_d2dbvo2__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1ceta2_d4kdea2__1			Apicomplexa	Deinococcus-Thermus	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]			L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]
d1cevf__d3nipf___1			Firmicutes	Proteobacteria	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]			arginase activity [GO:0004053]; metal ion binding [GO:0046872]	agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]
d1cexa__d5ajhb1__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	cutinase activity [GO:0050525]	cutinase activity [GO:0050525]
d1cexa__d5frda1__1	Fungi		Ascomycota	Euryarchaeota	extracellular region [GO:0005576]; cutinase activity [GO:0050525]				extracellular region [GO:0005576]		cutinase activity [GO:0050525]	
d1ceya__d4q7eb___1			Proteobacteria		cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	
d1cf1d1_d1g4mb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]; G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; acetylcholine receptor binding [GO:0033130]; AP-2 adaptor complex binding [GO:0035612]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein homodimerization activity [GO:0042803]; clathrin-dependent endocytosis [GO:0072583]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	clathrin-dependent endocytosis [GO:0072583]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]	G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]	acetylcholine receptor binding [GO:0033130]; AP-2 adaptor complex binding [GO:0035612]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein homodimerization activity [GO:0042803]
d1cf2o2_d1vjpa4__1			Euryarchaeota		cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]		glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]		4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	
d1cf2q2_d1rm0b2__1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; inositol-3-phosphate synthase activity [GO:0004512]; inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	inositol-3-phosphate synthase activity [GO:0004512]
d1cf4a__d1ob5a3__1	Metazoa		Chordata	Deinococcus-Thermus	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]		apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	cytoplasm [GO:0005737]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1cf6a3_d2isoa1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]		damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d1cf8h2_d3rpib1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1cf8l1_d4hjga1__1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]
d1cf9a1_d2r1ta___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]
d1cfca__d1aj4a___1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	calcium-mediated signaling [GO:0019722]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]		troponin complex [GO:0005861]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]
d1cfea__d2ddba1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular space [GO:0005615]; defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]		extracellular space [GO:0005615]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1cfna1_d1fskb2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1cfnb1_d4pljl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell cytoplasm [GO:0030430]; host cell surface [GO:0044228]; viral capsid [GO:0019028]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell cytoplasm [GO:0030430]; host cell surface [GO:0044228]; viral capsid [GO:0019028]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1cfnb2_d5m00g1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1cfpb__d4xjki___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1cfqa1_d1ncdl2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1cfqa2_d4z7ug1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	nutrient reservoir activity [GO:0045735]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	nutrient reservoir activity [GO:0045735]
d1cfqb2_d2dqgl___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1cfra__d3v20b___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	endonuclease activity [GO:0004519]	DNA restriction-modification system [GO:0009307]				metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]	endonuclease activity [GO:0004519]
d1cfsa2_d1ggim1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1cfsb1_d4c83b2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1cfsb2_d2f8vd2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1cfta1_d5k59f1__1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; cytolysis in other organism [GO:0051715]; pathogenesis [GO:0009405]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytolysis in other organism [GO:0051715]; pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1cfta2_d5hggt1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	serine-type endopeptidase activity [GO:0004252]
d1cftb1_d2vita1__1	Metazoa		Chordata	Negarnaviricota	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	host cell surface receptor binding [GO:0046789]
d1cftb1_d5vcoc2__1	Metazoa	Metazoa	Chordata	Arthropoda	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cysteine-type peptidase activity [GO:0008234]
d1cftb2_d3cfje1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1cfyb__d1wm4a___1	Fungi	Metazoa	Ascomycota	Chordata	actin cortical patch [GO:0030479]; actin cytoskeleton [GO:0015629]; nuclear matrix [GO:0016363]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]; defense response to fungus [GO:0050832]; regulation of actin filament polymerization [GO:0030833]	actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]	defense response to fungus [GO:0050832]; regulation of actin filament polymerization [GO:0030833]	actin cortical patch [GO:0030479]; actin cytoskeleton [GO:0015629]; nuclear matrix [GO:0016363]; plasma membrane [GO:0005886]	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	actin filament binding [GO:0051015]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]
d1cg5a__d3ubcg___1	Metazoa		Chordata	Verrucomicrobia	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1cg8a__d3goub___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1cg9b1_d4m7kl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1cg9b1_d5e5mf___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1cgea__d1kapp2__1	Metazoa		Chordata	Proteobacteria	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]; negative regulation of complement activation, classical pathway [GO:0045959]; negative regulation of complement activation, lectin pathway [GO:0001869]; pathogenesis [GO:0009405]; positive regulation of sodium ion transport [GO:0010765]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	negative regulation of complement activation, classical pathway [GO:0045959]; negative regulation of complement activation, lectin pathway [GO:0001869]; pathogenesis [GO:0009405]; positive regulation of sodium ion transport [GO:0010765]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]
d1cgea__d2d1ob___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1cgfb__d1iaca___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cortical granule [GO:0060473]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; aspartic-type peptidase activity [GO:0070001]; glutamic-type peptidase activity [GO:0070002]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]; cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	cortical granule [GO:0060473]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	aspartic-type peptidase activity [GO:0070001]; glutamic-type peptidase activity [GO:0070002]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]
d1cgje__d2f9pa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	digestion [GO:0007586]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1cgka2_d4z8da1__1	Viridiplantae		Streptophyta	Proteobacteria	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		cytosol [GO:0005829]	naringenin-chalcone synthase activity [GO:0016210]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1cgla__d5n5ja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1cgna__d2j9ba___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1cgpb2_d2bgch2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; pathogenesis [GO:0009405]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	pathogenesis [GO:0009405]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1cgqa__d4osfb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d1cgsh1_d1bqhg___1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1cgsh1_d1qvoe1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1cgsh2_d2vlra1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1cgsl1_d5vzyl2__1	Metazoa	Metazoa	Chordata	Chordata		extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]		extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		
d1cgta1_d5e80b___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	carbohydrate metabolic process [GO:0005975]	response to stimulus [GO:0050896]; visual perception [GO:0007601]	extracellular region [GO:0005576]	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]
d1cgta4_d3cufa___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]
d1cgua1_d2o93o1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	carbohydrate metabolic process [GO:0005975]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1cgua2_d2xhna2__1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]
d1cgva1_d3o7ya1__1			Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	
d1cgva2_d3njxa2__1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]
d1cgwa1_d1gofa1__1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]
d1cgwa1_d2x6ca2__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; regulation of ion transmembrane transport [GO:0034765]	carbohydrate metabolic process [GO:0005975]	regulation of ion transmembrane transport [GO:0034765]	extracellular region [GO:0005576]	integral component of membrane [GO:0016021]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]
d1cgwa3_d3o7ya3__1			Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	
d1cgwa4_d1clva2__1		Metazoa	Firmicutes	Arthropoda	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1cgwa4_d1e0wa___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d1cgxa1_d1uktb1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1cgxa1_d2bzdc2__1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]	metabolic process [GO:0008152]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1cgxa4_d4m82a___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]; cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	carbohydrate metabolic process [GO:0005975]	cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]
d1cgya1_d2fh6a1__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	plasma membrane [GO:0005886]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]
d1cgya3_d1g1yb2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1cgza2_d1tqya1__1	Viridiplantae		Streptophyta	Actinobacteria	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]			naringenin-chalcone synthase activity [GO:0016210]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1ch0a__d1i70a___1	Fungi		Ascomycota	Actinobacteria	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1ch2a1_d1mkoc___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ch4b__d1y85d___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ch6f1_d1c1xb2__1				Actinobacteria		nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]		L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]				nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d1chma1_d1m35f1__1			Proteobacteria	Proteobacteria	creatinase activity [GO:0016980]	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]				cytosol [GO:0005829]	creatinase activity [GO:0016980]	aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]
d1cho.1_d3govb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; peptidase activity [GO:0008233]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; negative regulation of complement activation [GO:0045916]; receptor-mediated endocytosis [GO:0006898]	digestion [GO:0007586]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; negative regulation of complement activation [GO:0045916]; receptor-mediated endocytosis [GO:0006898]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; peptidase activity [GO:0008233]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]
d1chpe__d1uupb1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1chqf__d1bove___1			Proteobacteria		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]		galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	
d1chqg__d4l6tf1__1			Proteobacteria	Proteobacteria	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]		galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]
d1chrb4_d4mgga2__1				Proteobacteria		amino acid binding [GO:0016597]; hydro-lyase activity [GO:0016836]; isomerase activity [GO:0016853]; magnesium ion binding [GO:0000287]; alpha-amino acid metabolic process [GO:1901605]; cellular response to amino acid stimulus [GO:0071230]		alpha-amino acid metabolic process [GO:1901605]; cellular response to amino acid stimulus [GO:0071230]				amino acid binding [GO:0016597]; hydro-lyase activity [GO:0016836]; isomerase activity [GO:0016853]; magnesium ion binding [GO:0000287]
d1chua3_d1e7pj3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; flavin adenine dinucleotide binding [GO:0050660]; L-aspartate oxidase activity [GO:0008734]; L-aspartate:fumarate oxidoreductase activity [GO:0044318]; 'de novo' NAD biosynthetic process from aspartate [GO:0034628]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	'de novo' NAD biosynthetic process from aspartate [GO:0034628]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]	respirasome [GO:0070469]	flavin adenine dinucleotide binding [GO:0050660]; L-aspartate:fumarate oxidoreductase activity [GO:0044318]; L-aspartate oxidase activity [GO:0008734]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d1chwa2_d1u6ea1__1	Viridiplantae		Streptophyta	Actinobacteria	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		cytoplasm [GO:0005737]	naringenin-chalcone synthase activity [GO:0016210]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d1chwb2_d5wx5e1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	biosynthetic process [GO:0009058]			naringenin-chalcone synthase activity [GO:0016210]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1ci1a__d4g1kb___1				Proteobacteria	glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycosome [GO:0020015]	cytoplasm [GO:0005737]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1ci3m2_d1e2zb2__1		Viridiplantae	Cyanobacteria	Chlorophyta	integral component of thylakoid membrane [GO:0031361]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]; chloroplast thylakoid membrane [GO:0009535]; integral component of thylakoid membrane [GO:0031361]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	photosynthesis [GO:0015979]	photosynthesis [GO:0015979]	integral component of thylakoid membrane [GO:0031361]	chloroplast [GO:0009507]; chloroplast thylakoid membrane [GO:0009535]; integral component of thylakoid membrane [GO:0031361]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1ci5a1_d2r9hd2__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; signaling receptor binding [GO:0005102]; cell-cell adhesion [GO:0098609]; cellular response to interferon-gamma [GO:0071346]; cellular response to tumor necrosis factor [GO:0071356]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cell-cell adhesion [GO:0098609]; cellular response to interferon-gamma [GO:0071346]; cellular response to tumor necrosis factor [GO:0071356]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	signaling receptor binding [GO:0005102]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1cica1_d4k2um1__1	Metazoa		Chordata	Apicomplexa	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; microneme [GO:0020009]; heparin binding [GO:0008201]; host cell surface receptor binding [GO:0046789]; entry into host cell [GO:0030260]; pathogenesis [GO:0009405]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	entry into host cell [GO:0030260]; pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; microneme [GO:0020009]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	heparin binding [GO:0008201]; host cell surface receptor binding [GO:0046789]
d1cicb1_d2a9mm___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1cicb2_d1od7a___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	carbohydrate binding [GO:0030246]
d1cicc1_d1wiqa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1cicd1_d1c16f___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1cicd2_d5sv4b1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1cida1_d3umta2__1	Metazoa		Chordata		cell [GO:0005623]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor binding [GO:0005102]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell selection [GO:0045058]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell selection [GO:0045058]		cell [GO:0005623]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		coreceptor activity [GO:0015026]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor binding [GO:0005102]; zinc ion binding [GO:0008270]	
d1cija__d1jjid___1			Proteobacteria	Euryarchaeota	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	hydrolase activity [GO:0016787]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]				haloalkane dehalogenase activity [GO:0018786]	hydrolase activity [GO:0016787]
d1ciua1_d7cgta1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1ciua2_d2j43a2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]
d1ciua3_d3hg2a2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d1ciwd__d2zglb1__1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]		apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d1ciya2_d4aryd2__1			Firmicutes	Firmicutes	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]			signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d1cj1b__d2rvfa1__1	Metazoa		Chordata		cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]		aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]		cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]		ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	
d1cj1j__d1b47c3__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]
d1cj3a2_d2v5zb2__1		Metazoa	Proteobacteria	Chordata	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1cj4a2_d2c67a2__1		Metazoa	Proteobacteria	Chordata	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1cj5a__d3fa9a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	extracellular region [GO:0005576]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1cj8a__d1yaoa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1cj8a__d2q9da___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1cjba__d3lrtb2__1			Apicomplexa	Euryarchaeota	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; xanthine phosphoribosyltransferase activity [GO:0000310]; GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; xanthine phosphoribosyltransferase activity [GO:0000310]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]
d1cjca1_d1gt8c3__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; NADPH-adrenodoxin reductase activity [GO:0015039]; cholesterol metabolic process [GO:0008203]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; ubiquinone biosynthetic process [GO:0006744]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cholesterol metabolic process [GO:0008203]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; ubiquinone biosynthetic process [GO:0006744]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; NADPH-adrenodoxin reductase activity [GO:0015039]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d1cjdb1_d2bvih2__1					viral capsid [GO:0019028]; virion [GO:0019012]				viral capsid [GO:0019028]; virion [GO:0019012]			
d1cjdb2_d1m3yc2__1					viral capsid [GO:0019028]; virion [GO:0019012]				viral capsid [GO:0019028]; virion [GO:0019012]			
d1cjdc1_d3tg7a2__1					viral capsid [GO:0019028]; virion [GO:0019012]	host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]; viral capsid [GO:0019028]; structural molecule activity [GO:0005198]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]		microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]	viral capsid [GO:0019028]; virion [GO:0019012]	host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]; viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d1cjea__d1qoba___1	Metazoa		Chordata	Cyanobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1cjea__d4ltub___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1cjeb__d3b2ga___1	Metazoa		Chordata	Cyanobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1cjec__d3p4pb1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1cjed__d1qlbb2__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d1cjkc1_d3umra1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; protein folding [GO:0006457]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]; response to peptide hormone [GO:0043434]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; protein folding [GO:0006457]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]; response to peptide hormone [GO:0043434]	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d1cjpd__d2dvfb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1cjpd__d3vkla2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d1cjwa__d2veza___1	Metazoa	Fungi	Chordata	Ascomycota	perinuclear region of cytoplasm [GO:0048471]; aralkylamine N-acetyltransferase activity [GO:0004059]; cellular response to cAMP [GO:0071320]; circadian rhythm [GO:0007623]; melatonin biosynthetic process [GO:0030187]; N-terminal protein amino acid acetylation [GO:0006474]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cellular response to cAMP [GO:0071320]; circadian rhythm [GO:0007623]; melatonin biosynthetic process [GO:0030187]; N-terminal protein amino acid acetylation [GO:0006474]	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	perinuclear region of cytoplasm [GO:0048471]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]	aralkylamine N-acetyltransferase activity [GO:0004059]	glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]
d1cjxa1_d1kw6b2__1			Proteobacteria	Proteobacteria	4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]			4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]
d1cjxb1_d3ojkc2__1			Proteobacteria	Actinobacteria	4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]				4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1cjxc1_d1dhya1__1			Proteobacteria	Proteobacteria	4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]			4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]
d1cjxd2_d1jc5d___1			Proteobacteria	Actinobacteria	4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	methylmalonyl-CoA epimerase activity [GO:0004493]	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]				4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]	methylmalonyl-CoA epimerase activity [GO:0004493]
d1cjxd2_d2igac2__1			Proteobacteria	Actinobacteria	4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]				4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1cjyb1_d5bugc2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; calcium-dependent phospholipid binding [GO:0005544]; lysophospholipase activity [GO:0004622]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; cardiolipin acyl-chain remodeling [GO:0035965]; cellular response to antibiotic [GO:0071236]; glycerophospholipid catabolic process [GO:0046475]; icosanoid biosynthetic process [GO:0046456]; icosanoid metabolic process [GO:0006690]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; platelet activating factor biosynthetic process [GO:0006663]; regulation of cell population proliferation [GO:0042127]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; ubiquitin-specific protease binding [GO:1990381]; adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; cardiolipin acyl-chain remodeling [GO:0035965]; cellular response to antibiotic [GO:0071236]; glycerophospholipid catabolic process [GO:0046475]; icosanoid biosynthetic process [GO:0046456]; icosanoid metabolic process [GO:0006690]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; platelet activating factor biosynthetic process [GO:0006663]; regulation of cell population proliferation [GO:0042127]	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; lysophospholipase activity [GO:0004622]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]	anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381]
d1ck1a1_d5elej___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d1ck1a2_d3seba2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1ckda__d1jqub___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ckfa__d3b6la___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ckfa__d4emnb___1	Metazoa		Chordata	Actinobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; dormancy exit of symbiont in host [GO:0085016]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	dormancy exit of symbiont in host [GO:0085016]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	hydrolase activity [GO:0016787]
d1ckga__d1pqda___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ckgb__d3fi5d___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ckha__d3iwra___1	Metazoa	Viridiplantae	Chordata	Streptophyta	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; polysaccharide catabolic process [GO:0000272]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; polysaccharide catabolic process [GO:0000272]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d1ckoa2_d2q2uc2__1					GTP binding [GO:0005525]; mRNA guanylyltransferase activity [GO:0004484]; 7-methylguanosine mRNA capping [GO:0006370]	ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]	7-methylguanosine mRNA capping [GO:0006370]	DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]			GTP binding [GO:0005525]; mRNA guanylyltransferase activity [GO:0004484]	ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]
d1ckta__d2gzka2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 5S rRNA binding [GO:0008097]; bent DNA binding [GO:0003681]; bubble DNA binding [GO:0000405]; crossed form four-way junction DNA binding [GO:0000402]; cytokine activity [GO:0005125]; DNA binding, bending [GO:0008301]; double-stranded DNA binding [GO:0003690]; four-way junction DNA binding [GO:0000400]; glycolipid binding [GO:0051861]; heparin binding [GO:0008201]; open form four-way junction DNA binding [GO:0000401]; peptide binding [GO:0042277]; protein dimerization activity [GO:0046983]; RAGE receptor binding [GO:0050786]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription factor binding [GO:0008134]; actin cytoskeleton reorganization [GO:0031532]; activation of innate immune response [GO:0002218]; adaptive immune response [GO:0002250]; apoptotic cell clearance [GO:0043277]; autophagy [GO:0006914]; cell chemotaxis [GO:0060326]; cell morphogenesis [GO:0000902]; cellular response to interleukin-1 [GO:0071347]; chemotaxis [GO:0006935]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; DNA geometric change [GO:0032392]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; male-specific defense response to bacterium [GO:0050831]; myoblast proliferation [GO:0051450]; negative regulation of DNA replication [GO:0008156]; nervous system development [GO:0007399]; neuron projection development [GO:0031175]; neutrophil clearance [GO:0097350]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA ligation [GO:0051106]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-1 secretion [GO:0050716]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage inflammatory protein 1 alpha production [GO:0071642]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of myeloid cell apoptotic process [GO:0033034]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of inflammatory response [GO:0050727]; regulation of signaling receptor activity [GO:0010469]; regulation of T cell mediated immune response to tumor cell [GO:0002840]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to insulin [GO:0032868]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; calmodulin binding [GO:0005516]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; transcription factor binding [GO:0008134]; cell differentiation [GO:0030154]; male sex determination [GO:0030238]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of male gonad development [GO:2000020]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; sex differentiation [GO:0007548]	actin cytoskeleton reorganization [GO:0031532]; activation of innate immune response [GO:0002218]; adaptive immune response [GO:0002250]; apoptotic cell clearance [GO:0043277]; autophagy [GO:0006914]; cell chemotaxis [GO:0060326]; cell morphogenesis [GO:0000902]; cellular response to interleukin-1 [GO:0071347]; chemotaxis [GO:0006935]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; DNA geometric change [GO:0032392]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; male-specific defense response to bacterium [GO:0050831]; myoblast proliferation [GO:0051450]; negative regulation of DNA replication [GO:0008156]; nervous system development [GO:0007399]; neuron projection development [GO:0031175]; neutrophil clearance [GO:0097350]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA ligation [GO:0051106]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-1 secretion [GO:0050716]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage inflammatory protein 1 alpha production [GO:0071642]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of myeloid cell apoptotic process [GO:0033034]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of inflammatory response [GO:0050727]; regulation of signaling receptor activity [GO:0010469]; regulation of T cell mediated immune response to tumor cell [GO:0002840]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to insulin [GO:0032868]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]	cell differentiation [GO:0030154]; male sex determination [GO:0030238]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of male gonad development [GO:2000020]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; sex differentiation [GO:0007548]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5S rRNA binding [GO:0008097]; bent DNA binding [GO:0003681]; bubble DNA binding [GO:0000405]; crossed form four-way junction DNA binding [GO:0000402]; cytokine activity [GO:0005125]; DNA binding, bending [GO:0008301]; double-stranded DNA binding [GO:0003690]; four-way junction DNA binding [GO:0000400]; glycolipid binding [GO:0051861]; heparin binding [GO:0008201]; open form four-way junction DNA binding [GO:0000401]; peptide binding [GO:0042277]; protein dimerization activity [GO:0046983]; RAGE receptor binding [GO:0050786]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription factor binding [GO:0008134]	calmodulin binding [GO:0005516]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; transcription factor binding [GO:0008134]
d1cl0a2_d1d5ta1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; flavin adenine dinucleotide binding [GO:0050660]; thioredoxin-disulfide reductase activity [GO:0004791]; removal of superoxide radicals [GO:0019430]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; midbody [GO:0030496]; GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]; negative regulation of axonogenesis [GO:0050771]; negative regulation of protein targeting to membrane [GO:0090315]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192]	removal of superoxide radicals [GO:0019430]	negative regulation of axonogenesis [GO:0050771]; negative regulation of protein targeting to membrane [GO:0090315]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; midbody [GO:0030496]	flavin adenine dinucleotide binding [GO:0050660]; thioredoxin-disulfide reductase activity [GO:0004791]	GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]
d1cl2a__d5xmub___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; methionine biosynthetic process [GO:0009086]; transsulfuration [GO:0019346]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	methionine biosynthetic process [GO:0009086]; transsulfuration [GO:0019346]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]		cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d1cl2b__d1i48c___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; methionine biosynthetic process [GO:0009086]; transsulfuration [GO:0019346]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	methionine biosynthetic process [GO:0009086]; transsulfuration [GO:0019346]	transsulfuration [GO:0019346]	cytoplasm [GO:0005737]		cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d1cl7.1_d1m05a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1cl7.1_d3bp5a___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1cl7h1_d1ikfl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1cl7l2_d3nfsl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1cl7l2_d4irjd1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1clca1_d5gy0a1__1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1clca2_d1rq5a2__1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d1clia1_d5vk4b1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]	ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]
d1clic2_d3d54i4__1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]
d1clic2_d5avma1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]	ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]
d1clid1_d2v9ya1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d1clid2_d5avme1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]	ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]
d1clka__d1dieb___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1clla__d1rtp2___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cochlea development [GO:0090102]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cochlea development [GO:0090102]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d1clol2_d2h9gl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]
d1clpb__d1goda___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]
d1clsc__d3kunb___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d1clva2_d2vzoa3__1	Metazoa		Arthropoda	Actinobacteria	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate catabolic process [GO:0016052]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1clxd__d1e1ea___1		Viridiplantae	Proteobacteria	Streptophyta	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]		chloroplast [GO:0009507]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]	beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]
d1clyl2_d2ak4q1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1clzh1_d1olla1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; immunoglobulin receptor binding [GO:0034987]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; SWI/SNF complex [GO:0016514]; cellular defense response [GO:0006968]; natural killer cell activation [GO:0030101]; regulation of immune response [GO:0050776]; regulation of natural killer cell mediated cytotoxicity [GO:0042269]; signal transduction [GO:0007165]		cellular defense response [GO:0006968]; natural killer cell activation [GO:0030101]; regulation of immune response [GO:0050776]; regulation of natural killer cell mediated cytotoxicity [GO:0042269]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; SWI/SNF complex [GO:0016514]	immunoglobulin receptor binding [GO:0034987]	
d1clzh2_d5acmb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; immunoglobulin receptor binding [GO:0034987]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]
d1clzl2_d1hzhm2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; immunoglobulin receptor binding [GO:0034987]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1clzl2_d5n88h___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; immunoglobulin receptor binding [GO:0034987]	cytosol [GO:0005829]; nuclear heterochromatin [GO:0005720]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; RNA binding [GO:0003723]; supercoiled DNA binding [GO:0097100]; transcription coactivator activity [GO:0003713]; establishment of integrated proviral latency [GO:0075713]; mRNA 5'-splice site recognition [GO:0000395]; nuclear transport [GO:0051169]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]		establishment of integrated proviral latency [GO:0075713]; mRNA 5'-splice site recognition [GO:0000395]; nuclear transport [GO:0051169]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; nuclear heterochromatin [GO:0005720]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	immunoglobulin receptor binding [GO:0034987]	activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; RNA binding [GO:0003723]; supercoiled DNA binding [GO:0097100]; transcription coactivator activity [GO:0003713]
d1cm0b__d5u08b___1	Metazoa		Chordata		A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]		A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]		acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]
d1cm2a__d1y51b___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]; enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	cytoplasm [GO:0005737]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]	cytoplasm [GO:0005737]	enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]	
d1cm5b__d6r1ra2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; formate C-acetyltransferase activity [GO:0008861]; glucose metabolic process [GO:0006006]; threonine catabolic process [GO:0006567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	glucose metabolic process [GO:0006006]; threonine catabolic process [GO:0006567]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	formate C-acetyltransferase activity [GO:0008861]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1cmaa__d1mjqh___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]	cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1cmcb__d1mjka___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]	cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1cmfa__d5i0ic___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]; calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]; calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1cmga__d1mq1a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]; calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]; calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1cmna__d3k9vb___1	Fungi	Metazoa	Ascomycota	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity [GO:0030342]; 25-hydroxycholecalciferol-24-hydroxylase activity [GO:0008403]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; osteoblast differentiation [GO:0001649]; response to vitamin D [GO:0033280]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359]		osteoblast differentiation [GO:0001649]; response to vitamin D [GO:0033280]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359]		mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity [GO:0030342]; 25-hydroxycholecalciferol-24-hydroxylase activity [GO:0008403]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1cmqa__d5coxb1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1cmsa__d2whha2__1	Metazoa		Chordata		aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1cmta__d1prhb1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1cmua__d2rc0x___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1cmza__d4igua1__1	Metazoa	Metazoa	Chordata	Arthropoda	brush border [GO:0005903]; clathrin-coated vesicle [GO:0030136]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; G-protein alpha-subunit binding [GO:0001965]; GTPase activity [GO:0003924]; autophagy [GO:0006914]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; response to ethanol [GO:0045471]; small GTPase mediated signal transduction [GO:0007264]	G-protein alpha-subunit binding [GO:0001965]; GDP-dissociation inhibitor activity [GO:0005092]; GTPase activator activity [GO:0005096]; positive regulation of GTPase activity [GO:0043547]	autophagy [GO:0006914]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; response to ethanol [GO:0045471]; small GTPase mediated signal transduction [GO:0007264]	positive regulation of GTPase activity [GO:0043547]	brush border [GO:0005903]; clathrin-coated vesicle [GO:0030136]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		G-protein alpha-subunit binding [GO:0001965]; GTPase activity [GO:0003924]	GDP-dissociation inhibitor activity [GO:0005092]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]
d1cn1b__d1jojd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1cn3d__d3bwqa___1					host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]	capsomere [GO:0046727]; host cell endoplasmic reticulum [GO:0044165]; host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; protein homooligomerization [GO:0051260]; viral capsid assembly [GO:0019069]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; protein homooligomerization [GO:0051260]; viral capsid assembly [GO:0019069]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]	capsomere [GO:0046727]; host cell endoplasmic reticulum [GO:0044165]; host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]	structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1cn4a1_d5dftc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]
d1cn4a2_d2kbga___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	axon [GO:0030424]; integral component of membrane [GO:0016021]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; axonal fasciculation [GO:0007413]; neuron cell-cell adhesion [GO:0007158]; sensory perception of smell [GO:0007608]	brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	axonal fasciculation [GO:0007413]; neuron cell-cell adhesion [GO:0007158]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]	axon [GO:0030424]; integral component of membrane [GO:0016021]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]	erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]	identical protein binding [GO:0042802]
d1cnca__d1raza___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1cnea2_d1ndha2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]; FAD binding [GO:0071949]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; nitrate reductase (NADH) activity [GO:0009703]; nitrate assimilation [GO:0042128]; nitric oxide biosynthetic process [GO:0006809]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]	nitrate assimilation [GO:0042128]; nitric oxide biosynthetic process [GO:0006809]	cholesterol biosynthetic process [GO:0006695]	cytosol [GO:0005829]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	FAD binding [GO:0071949]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; nitrate reductase (NADH) activity [GO:0009703]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1cnfa1_d4e0fb1__1	Viridiplantae		Streptophyta	Proteobacteria	cytosol [GO:0005829]; FAD binding [GO:0071949]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; nitrate reductase (NADH) activity [GO:0009703]; nitrate assimilation [GO:0042128]; nitric oxide biosynthetic process [GO:0006809]	riboflavin binding [GO:1902444]; riboflavin synthase activity [GO:0004746]; protein homotrimerization [GO:0070207]; riboflavin biosynthetic process [GO:0009231]	nitrate assimilation [GO:0042128]; nitric oxide biosynthetic process [GO:0006809]	protein homotrimerization [GO:0070207]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]		FAD binding [GO:0071949]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; nitrate reductase (NADH) activity [GO:0009703]	riboflavin binding [GO:1902444]; riboflavin synthase activity [GO:0004746]
d1cnma__d1p8jd2__1	Fungi	Metazoa	Ascomycota	Chordata	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d1cnob__d1w2la___1			Proteobacteria	Bacteroidetes	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]			periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]
d1cnod__d1dw0a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1cnog__d1c52a___1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1cnog__d3l71d1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]			periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1cnpa__d5tp5a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; calcium ion binding [GO:0005509]; protein N-terminus binding [GO:0047485]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; protein N-terminus binding [GO:0047485]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1cnpb__d3ko0l___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; calcium ion binding [GO:0005509]; protein N-terminus binding [GO:0047485]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]		epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium ion binding [GO:0005509]; protein N-terminus binding [GO:0047485]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d1cnsa__d1cx7a___1	Viridiplantae		Streptophyta		chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]	chitinase activity [GO:0004568]	lysozyme activity [GO:0003796]
d1cnua__d1hqz4___1		Fungi		Ascomycota	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin filament binding [GO:0051015]; actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin filament depolymerization [GO:0030042]	actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	actin binding [GO:0003779]	actin filament binding [GO:0051015]
d1cnva__d1jdaa2__1	Viridiplantae		Streptophyta	Proteobacteria	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; starch catabolic process [GO:0005983]	carbohydrate metabolic process [GO:0005975]	starch catabolic process [GO:0005983]		extracellular region [GO:0005576]		glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1cnya__d4ygfe___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1co0b__d5tm0a___1			Proteobacteria		cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]		negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]		cytoplasm [GO:0005737]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	
d1co3b__d4i3xg___1				Proteobacteria		nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]						nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1co3c__d2onoc___1		Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d1co3c__d4qf6g___1												
d1co6a__d2oz1d___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	photosynthesis [GO:0015979]				electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1co7e__d3qgja___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]	serine-type endopeptidase activity [GO:0004252]
d1co9a__d3o89a___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1coka__d1z1va___1	Metazoa	Fungi	Chordata	Ascomycota	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cytoplasm [GO:0005737]; protein kinase regulator activity [GO:0019887]; SAM domain binding [GO:0032093]; cell cycle arrest [GO:0007050]; cellular response to heat [GO:0034605]; osmosensory signaling MAPK cascade [GO:0000161]; osmosensory signaling pathway via Sho1 osmosensor [GO:0007232]; pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0000750]; signal transduction involved in filamentous growth [GO:0001402]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cell cycle arrest [GO:0007050]; cellular response to heat [GO:0034605]; osmosensory signaling MAPK cascade [GO:0000161]; osmosensory signaling pathway via Sho1 osmosensor [GO:0007232]; pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0000750]; signal transduction involved in filamentous growth [GO:0001402]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	protein kinase regulator activity [GO:0019887]; SAM domain binding [GO:0032093]
d1comd__d1odeb___1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	chorismate mutase activity [GO:0004106]	chorismate mutase activity [GO:0004106]
d1comh__d1odec___1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	chorismate mutase activity [GO:0004106]	chorismate mutase activity [GO:0004106]
d1comk__d1ui9a___1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	chorismate mutase activity [GO:0004106]	chorismate mutase activity [GO:0004106]
d1cov1__d1yc6q___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1cov3__d4y4yr___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1cowa1_d3tgwa3__1	Metazoa		Chordata	Euryarchaeota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1cowb1_d1efre1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1cowb1_d3a5ca4__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1cowd2_d1e1rb2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1cowe2_d3a5cj1__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1cowf2_d2v7qc1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1coza__d3n2ya___1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]
d1cozb__d2b7ld___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cytoplasm [GO:0005737]; glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]	glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]
d1cp0a__d5nb3f___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1cp6a__d5lrka___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1cpb.1_d1ft7a___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	proteolysis [GO:0006508]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]
d1cpck__d1uiwb___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1cpea__d1yzra___1	Fungi	Fungi	Ascomycota	Basidiomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]
d1cpfa__d3n8ya2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1cpga__d3uw8a2__1	Fungi		Ascomycota	Euryarchaeota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1cpma__d1urxa___1			Firmicutes	Bacteroidetes	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; beta-agarase activity [GO:0033916]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	licheninase activity [GO:0042972]	beta-agarase activity [GO:0033916]
d1cpna__d4ym2c___1		Metazoa	Firmicutes	Chordata	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]	carbohydrate metabolic process [GO:0005975]	cell adhesion [GO:0007155]		collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	licheninase activity [GO:0042972]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d1cpra__d1jafa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1cq9b__d1teib___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1cq9c__d4yz5a1__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1cq9d__d1lgna___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1cqdb__d1npza___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cysteine-type peptidase activity [GO:0008234]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	cysteine-type peptidase activity [GO:0008234]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d1cqdb__d2aryb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cysteine-type peptidase activity [GO:0008234]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; mammary gland involution [GO:0060056]; neutrophil degranulation [GO:0043312]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; receptor catabolic process [GO:0032801]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of NMDA receptor activity [GO:2000310]; self proteolysis [GO:0097264]		cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; mammary gland involution [GO:0060056]; neutrophil degranulation [GO:0043312]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; receptor catabolic process [GO:0032801]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of NMDA receptor activity [GO:2000310]; self proteolysis [GO:0097264]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cysteine-type peptidase activity [GO:0008234]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d1cqdc__d1mira___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cysteine-type peptidase activity [GO:0008234]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; melanosome [GO:0042470]; mitochondrion [GO:0005739]; sarcolemma [GO:0042383]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; kininogen binding [GO:0030984]; peptide binding [GO:0042277]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; autophagy [GO:0006914]; cellular response to mechanical stimulus [GO:0071260]; negative regulation of cell death [GO:0060548]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of catalytic activity [GO:0050790]; response to amine [GO:0014075]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to interleukin-4 [GO:0070670]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to wounding [GO:0009611]; skeletal muscle tissue development [GO:0007519]; spermatogenesis [GO:0007283]		autophagy [GO:0006914]; cellular response to mechanical stimulus [GO:0071260]; negative regulation of cell death [GO:0060548]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of catalytic activity [GO:0050790]; response to amine [GO:0014075]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to interleukin-4 [GO:0070670]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to wounding [GO:0009611]; skeletal muscle tissue development [GO:0007519]; spermatogenesis [GO:0007283]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; melanosome [GO:0042470]; mitochondrion [GO:0005739]; sarcolemma [GO:0042383]	cysteine-type peptidase activity [GO:0008234]	cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; kininogen binding [GO:0030984]; peptide binding [GO:0042277]; protein-containing complex binding [GO:0044877]; protein self-association [GO:0043621]
d1cqdd__d2avwc___1	Viridiplantae		Streptophyta	Firmicutes	cysteine-type peptidase activity [GO:0008234]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]					cysteine-type peptidase activity [GO:0008234]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]
d1cqga__d1eohe2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1cqie1_d5caea2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]
d1cqie2_d2fpib2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]
d1cqjb2_d3rupa2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1cqjd2_d1cqib1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d1cqje2_d5bphc2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cytosol [GO:0005829]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1cqka__d3bkyh1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1cqkb__d5abdi___1		Metazoa		Chordata		actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]		blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]
d1cqra__d3kryc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1cqrb__d1c8ta___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1cqxa1_d1s5yc___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]		cytoplasm [GO:0005737]	hemoglobin complex [GO:0005833]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1cqxa2_d2vnkc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1cqxa3_d3qfca3__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1cqzb2_d5akla2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; peroxisome [GO:0005777]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d1cr5a1_d5ftjd1__1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi stack [GO:0005795]; mating projection tip [GO:0043332]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; phosphatidic acid binding [GO:0070300]; SNARE binding [GO:0000149]; autophagosome assembly [GO:0000045]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle docking [GO:0048211]; inter-Golgi cisterna vesicle-mediated transport [GO:0048219]; macroautophagy [GO:0016236]; SNARE complex disassembly [GO:0035494]; vacuole fusion, non-autophagic [GO:0042144]; vesicle fusion with Golgi apparatus [GO:0048280]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	autophagosome assembly [GO:0000045]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle docking [GO:0048211]; inter-Golgi cisterna vesicle-mediated transport [GO:0048219]; macroautophagy [GO:0016236]; SNARE complex disassembly [GO:0035494]; vacuole fusion, non-autophagic [GO:0042144]; vesicle fusion with Golgi apparatus [GO:0048280]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi stack [GO:0005795]; mating projection tip [GO:0043332]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; phosphatidic acid binding [GO:0070300]; SNARE binding [GO:0000149]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1cr5c1_d2jiqa1__1	Fungi		Ascomycota	Proteobacteria	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi stack [GO:0005795]; mating projection tip [GO:0043332]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; phosphatidic acid binding [GO:0070300]; SNARE binding [GO:0000149]; autophagosome assembly [GO:0000045]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle docking [GO:0048211]; inter-Golgi cisterna vesicle-mediated transport [GO:0048219]; macroautophagy [GO:0016236]; SNARE complex disassembly [GO:0035494]; vacuole fusion, non-autophagic [GO:0042144]; vesicle fusion with Golgi apparatus [GO:0048280]	periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	autophagosome assembly [GO:0000045]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle docking [GO:0048211]; inter-Golgi cisterna vesicle-mediated transport [GO:0048219]; macroautophagy [GO:0016236]; SNARE complex disassembly [GO:0035494]; vacuole fusion, non-autophagic [GO:0042144]; vesicle fusion with Golgi apparatus [GO:0048280]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi stack [GO:0005795]; mating projection tip [GO:0043332]	periplasmic space [GO:0042597]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; phosphatidic acid binding [GO:0070300]; SNARE binding [GO:0000149]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]
d1cr6a2_d3zwqa___1	Metazoa		Chordata	Crenarchaeota	cytosol [GO:0005829]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]	hydrolase activity [GO:0016787]	cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]		cytosol [GO:0005829]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	hydrolase activity [GO:0016787]
d1cr7a__d1s0ea1__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1cr7c__d4uw5c___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1cr7f__d3aycb1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d1cr9l2_d5ifhh1__1												
d1crcb__d4j20a___1	Metazoa		Chordata	Chlorobi	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	photosynthesis [GO:0015979]	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]		electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1crka2_d1htog2__1	Metazoa		Chordata	Actinobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; phosphocreatine biosynthetic process [GO:0046314]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	phosphocreatine biosynthetic process [GO:0046314]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1crya__d2c1de1__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	photosynthesis [GO:0015979]				electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1cs0a5_d1jkje2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d1cs0c2_d2b1ib1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1cs0c4_d4i4tf1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1cs0e5_d1iowa2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1cs0g2_d1pkxb1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1cs0g3_d4egqc1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1cs6a1_d1epfa2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; neuron cell-cell adhesion [GO:0007158]; presynaptic membrane organization [GO:0097090]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	neuron cell-cell adhesion [GO:0007158]; presynaptic membrane organization [GO:0097090]	aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	anchored component of membrane [GO:0031225]; plasma membrane [GO:0005886]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	cell adhesion molecule binding [GO:0050839]	cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]
d1cs6a1_d4liql1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; neuron cell-cell adhesion [GO:0007158]; presynaptic membrane organization [GO:0097090]	cell surface [GO:0009986]; CSF1-CSF1R complex [GO:1990682]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; cytokine binding [GO:0019955]; macrophage colony-stimulating factor receptor activity [GO:0005011]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; axon guidance [GO:0007411]; cell population proliferation [GO:0008283]; cell-cell junction maintenance [GO:0045217]; cellular response to cytokine stimulus [GO:0071345]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cytokine-mediated signaling pathway [GO:0019221]; forebrain neuron differentiation [GO:0021879]; hematopoietic progenitor cell differentiation [GO:0002244]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage colony-stimulating factor signaling pathway [GO:0038145]; macrophage differentiation [GO:0030225]; mammary gland duct morphogenesis [GO:0060603]; microglial cell proliferation [GO:0061518]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; olfactory bulb development [GO:0021772]; osteoclast differentiation [GO:0030316]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation by host of viral process [GO:0044794]; positive regulation of cell migration [GO:0030335]; positive regulation of cell motility [GO:2000147]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bone resorption [GO:0045124]; regulation of cell shape [GO:0008360]; response to ischemia [GO:0002931]; ruffle organization [GO:0031529]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	neuron cell-cell adhesion [GO:0007158]; presynaptic membrane organization [GO:0097090]	axon guidance [GO:0007411]; cell-cell junction maintenance [GO:0045217]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cytokine-mediated signaling pathway [GO:0019221]; forebrain neuron differentiation [GO:0021879]; hematopoietic progenitor cell differentiation [GO:0002244]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage colony-stimulating factor signaling pathway [GO:0038145]; macrophage differentiation [GO:0030225]; mammary gland duct morphogenesis [GO:0060603]; microglial cell proliferation [GO:0061518]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; olfactory bulb development [GO:0021772]; osteoclast differentiation [GO:0030316]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation by host of viral process [GO:0044794]; positive regulation of cell migration [GO:0030335]; positive regulation of cell motility [GO:2000147]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bone resorption [GO:0045124]; regulation of cell shape [GO:0008360]; response to ischemia [GO:0002931]; ruffle organization [GO:0031529]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	anchored component of membrane [GO:0031225]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; CSF1-CSF1R complex [GO:1990682]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell adhesion molecule binding [GO:0050839]	ATP binding [GO:0005524]; cytokine binding [GO:0019955]; macrophage colony-stimulating factor receptor activity [GO:0005011]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1cs6a2_d1tqcc2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; neuron cell-cell adhesion [GO:0007158]; presynaptic membrane organization [GO:0097090]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	neuron cell-cell adhesion [GO:0007158]; presynaptic membrane organization [GO:0097090]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	anchored component of membrane [GO:0031225]; plasma membrane [GO:0005886]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	cell adhesion molecule binding [GO:0050839]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d1cs6a4_d3nabl1__1	Metazoa		Chordata		anchored component of membrane [GO:0031225]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; neuron cell-cell adhesion [GO:0007158]; presynaptic membrane organization [GO:0097090]		neuron cell-cell adhesion [GO:0007158]; presynaptic membrane organization [GO:0097090]		anchored component of membrane [GO:0031225]; plasma membrane [GO:0005886]		cell adhesion molecule binding [GO:0050839]	
d1csb.1_d4qbba___1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1csee__d3gt4a___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1csga1_d1cd9c___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]	cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]
d1csia__d4jafb___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]; carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; citrate (Si)-synthase activity [GO:0004108]; identical protein binding [GO:0042802]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]	citrate (Si)-synthase activity [GO:0004108]; identical protein binding [GO:0042802]
d1csoe__d1wofb1__1			Actinobacteria		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular region [GO:0005576]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1ct1e__d1sbbb1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1ct1f__d4fo2f___1			Proteobacteria	Proteobacteria	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ct8a1_d3vg0l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ct8c1_d5d1zh2__1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]
d1ct8d2_d3q6fg2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ct9a2_d1ecja2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; aspartate-ammonia ligase activity [GO:0004071]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; asparagine biosynthetic process [GO:0006529]; cellular amino acid biosynthetic process [GO:0008652]; cellular amino acid catabolic process [GO:0009063]; glutamine metabolic process [GO:0006541]; L-asparagine biosynthetic process [GO:0070981]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	asparagine biosynthetic process [GO:0006529]; cellular amino acid biosynthetic process [GO:0008652]; cellular amino acid catabolic process [GO:0009063]; glutamine metabolic process [GO:0006541]; L-asparagine biosynthetic process [GO:0070981]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; aspartate-ammonia ligase activity [GO:0004071]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]
d1ctfa__d3dnjb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; large ribosomal subunit [GO:0015934]; protein homodimerization activity [GO:0042803]; ribosome binding [GO:0043022]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	translation [GO:0006412]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; large ribosomal subunit [GO:0015934]		protein homodimerization activity [GO:0042803]; ribosome binding [GO:0043022]; structural constituent of ribosome [GO:0003735]	
d1ctta2_d1jtka___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; pyrimidine nucleoside binding [GO:0001884]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]	cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; nucleobase-containing small molecule interconversion [GO:0015949]	cytidine deamination [GO:0009972]	cytosol [GO:0005829]	cytosol [GO:0005829]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; pyrimidine nucleoside binding [GO:0001884]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]
d1ctua1_d1wn5d___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; pyrimidine nucleoside binding [GO:0001884]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; nucleobase-containing small molecule interconversion [GO:0015949]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; nucleobase-containing small molecule interconversion [GO:0015949]	response to antibiotic [GO:0046677]	cytosol [GO:0005829]		cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; pyrimidine nucleoside binding [GO:0001884]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d1ctwa__d3tmva___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1cu1a1_d1p3ca___1				Firmicutes	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	serine-type endopeptidase activity [GO:0004252]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]
d1cu1a2_d1m34p___1				Proteobacteria	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	nitrogen fixation [GO:0009399]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1cu4h1_d1agda1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1cu4l1_d4gftb___1				Apicomplexa		inner membrane pellicle complex [GO:0070258]; calcium ion binding [GO:0005509]				inner membrane pellicle complex [GO:0070258]		calcium ion binding [GO:0005509]
d1cu6a__d4gn3o___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1cuda__d1a7ub___1	Fungi		Ascomycota	Actinobacteria	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	chloride peroxidase activity [GO:0016691]			extracellular region [GO:0005576]		cutinase activity [GO:0050525]	chloride peroxidase activity [GO:0016691]
d1cuea__d1cudc___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	cutinase activity [GO:0050525]	cutinase activity [GO:0050525]
d1cuia__d1agya___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	cutinase activity [GO:0050525]	cutinase activity [GO:0050525]
d1cuna1_d1u4qa2__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; actin filament capping [GO:0051693]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; actin filament capping [GO:0051693]	actin filament capping [GO:0051693]	actin filament capping [GO:0051693]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]
d1cuna2_d1u5pa1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; actin filament capping [GO:0051693]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; actin filament capping [GO:0051693]	actin filament capping [GO:0051693]	actin filament capping [GO:0051693]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]
d1cunb2_d3f31b___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; actin filament capping [GO:0051693]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; specific granule lumen [GO:0035580]; spectrin [GO:0008091]; tertiary granule lumen [GO:1904724]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; structural constituent of cytoskeleton [GO:0005200]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]; neutrophil degranulation [GO:0043312]	actin filament capping [GO:0051693]	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]; neutrophil degranulation [GO:0043312]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; specific granule lumen [GO:0035580]; spectrin [GO:0008091]; tertiary granule lumen [GO:1904724]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; structural constituent of cytoskeleton [GO:0005200]
d1cunc1_d5j4oa1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; actin filament capping [GO:0051693]	actin cytoskeleton [GO:0015629]; axon [GO:0030424]; cuticular plate [GO:0032437]; cytosol [GO:0005829]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; actin filament capping [GO:0051693]; actin filament organization [GO:0007015]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; hemopoiesis [GO:0030097]; lymphocyte homeostasis [GO:0002260]; MAPK cascade [GO:0000165]; plasma membrane organization [GO:0007009]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of protein binding [GO:0032092]; positive regulation of T cell proliferation [GO:0042102]; regulation of cell shape [GO:0008360]	actin filament capping [GO:0051693]	actin filament capping [GO:0051693]; actin filament organization [GO:0007015]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; hemopoiesis [GO:0030097]; lymphocyte homeostasis [GO:0002260]; MAPK cascade [GO:0000165]; plasma membrane organization [GO:0007009]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of protein binding [GO:0032092]; positive regulation of T cell proliferation [GO:0042102]; regulation of cell shape [GO:0008360]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]	actin cytoskeleton [GO:0015629]; axon [GO:0030424]; cuticular plate [GO:0032437]; cytosol [GO:0005829]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1cuoa__d1ocoo1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]		ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1cuua__d2psfa___1	Fungi	Metazoa	Ascomycota	Cnidaria	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	carboxy-lyase activity [GO:0016831]; Renilla-luciferin 2-monooxygenase activity [GO:0050248]; bioluminescence [GO:0008218]		bioluminescence [GO:0008218]	extracellular region [GO:0005576]		cutinase activity [GO:0050525]	carboxy-lyase activity [GO:0016831]; Renilla-luciferin 2-monooxygenase activity [GO:0050248]
d1cuva__d1cuxa___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	cutinase activity [GO:0050525]	cutinase activity [GO:0050525]
d1cuwa__d5tnja___1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	hydrolase activity [GO:0016787]			extracellular region [GO:0005576]		cutinase activity [GO:0050525]	hydrolase activity [GO:0016787]
d1cuwb__d1jjfa___1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan endo-1,3-beta-xylosidase activity [GO:0033905]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		cutinase activity [GO:0050525]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan endo-1,3-beta-xylosidase activity [GO:0033905]
d1cuxa__d3muna2__1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			extracellular region [GO:0005576]		cutinase activity [GO:0050525]	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d1cv2a__d1cqwa___1			Proteobacteria	Actinobacteria	periplasmic space [GO:0042597]; haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	haloalkane dehalogenase activity [GO:0018786]	response to toxic substance [GO:0009636]		periplasmic space [GO:0042597]		haloalkane dehalogenase activity [GO:0018786]	haloalkane dehalogenase activity [GO:0018786]
d1cv3a__d1f6sd___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	host cell cytoplasm [GO:0030430]	extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]
d1cv4a__d2yssc___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1cv5a__d215la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1cv6a__d1lz6a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1cvba__d3rg4a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1cvea__d4cnxa___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1cvfa__d3iaib___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1cvia__d5vvea1__1	Metazoa		Chordata	Heterolobosea	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]; adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]	adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	glycolytic process [GO:0006096]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]		5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]	phosphoglycerate mutase activity [GO:0004619]
d1cvib__d2p78a___1	Metazoa		Chordata	Deinococcus-Thermus	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]; adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	catalytic activity [GO:0003824]	adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]		azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]		5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]	catalytic activity [GO:0003824]
d1cvid__d1fzta___1	Metazoa	Fungi	Chordata	Ascomycota	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]; adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	cytosol [GO:0005829]; nucleus [GO:0005634]; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]	adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	cytosol [GO:0005829]; nucleus [GO:0005634]	5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; phosphoglycerate mutase activity [GO:0004619]
d1cvja2_d2msta___1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; identical protein binding [GO:0042802]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; response to hormone [GO:0009725]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	response to hormone [GO:0009725]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]	identical protein binding [GO:0042802]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]
d1cvja2_d3n9uc___1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; cell differentiation [GO:0030154]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA 3'-end processing [GO:0031124]; mRNA alternative polyadenylation [GO:0110104]; mRNA polyadenylation [GO:0006378]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA cleavage [GO:0031439]; positive regulation of mRNA polyadenylation [GO:1900365]; positive regulation of pro-B cell differentiation [GO:2000975]; positive regulation of stem cell differentiation [GO:2000738]; posttranscriptional regulation of gene expression [GO:0010608]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; termination of RNA polymerase II transcription [GO:0006369]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	cell differentiation [GO:0030154]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA 3'-end processing [GO:0031124]; mRNA alternative polyadenylation [GO:0110104]; mRNA polyadenylation [GO:0006378]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA cleavage [GO:0031439]; positive regulation of mRNA polyadenylation [GO:1900365]; positive regulation of pro-B cell differentiation [GO:2000975]; positive regulation of stem cell differentiation [GO:2000738]; posttranscriptional regulation of gene expression [GO:0010608]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; termination of RNA polymerase II transcription [GO:0006369]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]	chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d1cvjc1_d5uzmb___1	Metazoa	Metazoa	Chordata	Arthropoda	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	protein-containing complex [GO:0032991]; mRNA binding [GO:0003729]; chromosome organization [GO:0051276]; intracellular mRNA localization involved in pattern specification process [GO:0060810]; maternal specification of dorsal/ventral axis, oocyte, germ-line encoded [GO:0007311]; pole plasm oskar mRNA localization [GO:0045451]; regulation of translation [GO:0006417]; wound healing [GO:0042060]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	chromosome organization [GO:0051276]; intracellular mRNA localization involved in pattern specification process [GO:0060810]; maternal specification of dorsal/ventral axis, oocyte, germ-line encoded [GO:0007311]; pole plasm oskar mRNA localization [GO:0045451]; regulation of translation [GO:0006417]; wound healing [GO:0042060]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	protein-containing complex [GO:0032991]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]	mRNA binding [GO:0003729]
d1cvjc2_d4ed5b2__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]	AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d1cvjd1_d1kohc2__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1cvjd1_d3lqva___1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U12-type spliceosomal complex [GO:0005689]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; blastocyst formation [GO:0001825]; mRNA splicing, via spliceosome [GO:0000398]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	blastocyst formation [GO:0001825]; mRNA splicing, via spliceosome [GO:0000398]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U12-type spliceosomal complex [GO:0005689]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1cvje1_d2ghph2__1	Metazoa	Fungi	Chordata	Ascomycota	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]	RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]
d1cvje1_d2mgza1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	nuclear speck [GO:0016607]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; pre-mRNA intronic binding [GO:0097157]; single-stranded RNA binding [GO:0003727]; alternative mRNA splicing, via spliceosome [GO:0000380]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of locomotion [GO:0040012]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	alternative mRNA splicing, via spliceosome [GO:0000380]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of locomotion [GO:0040012]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	nuclear speck [GO:0016607]; ribonucleoprotein complex [GO:1990904]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]	mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; pre-mRNA intronic binding [GO:0097157]; single-stranded RNA binding [GO:0003727]
d1cvjg1_d2cpfa1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA binding [GO:0003723]; mRNA cis splicing, via spliceosome [GO:0045292]; multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	mRNA cis splicing, via spliceosome [GO:0045292]; multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]	RNA binding [GO:0003723]
d1cvjg1_d2dgua1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	catalytic step 2 spliceosome [GO:0071013]; CRD-mediated mRNA stability complex [GO:0070937]; endoplasmic reticulum [GO:0005783]; GAIT complex [GO:0097452]; histone pre-mRNA 3'end processing complex [GO:0071204]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 5'-UTR binding [GO:0048027]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; cellular response to interferon-gamma [GO:0071346]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of translation [GO:0017148]; osteoblast differentiation [GO:0001649]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; viral process [GO:0016032]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	cellular response to interferon-gamma [GO:0071346]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of translation [GO:0017148]; osteoblast differentiation [GO:0001649]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; viral process [GO:0016032]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	catalytic step 2 spliceosome [GO:0071013]; CRD-mediated mRNA stability complex [GO:0070937]; endoplasmic reticulum [GO:0005783]; GAIT complex [GO:0097452]; histone pre-mRNA 3'end processing complex [GO:0071204]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]	mRNA 5'-UTR binding [GO:0048027]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d1cvna__d2uwaa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	apoplast [GO:0048046]; cell wall [GO:0005618]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]; cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]		cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]		apoplast [GO:0048046]; cell wall [GO:0005618]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]
d1cvnb__d1dyka2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]		animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]		basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	signaling receptor binding [GO:0005102]
d1cvnc__d2w08c___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1cvnd__d3i4ib___1	Viridiplantae		Streptophyta		mannose binding [GO:0005537]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1cvsb__d3wo3i___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d1cvsc1_d5a3ih1__1	Metazoa		Chordata	Negarnaviricota	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d1cvsc2_d1orsb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1cvua1_d4fm5b2__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1cw3c__d4i1wd___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1cw3d__d3ifgl1__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	
d1cw4a__d1xcoc___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	acetyl-CoA biosynthetic process [GO:0006085]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	phosphate acetyltransferase activity [GO:0008959]
d1cw7a__d1j1wb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]
d1cwec__d2plea1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; intrinsic component of plasma membrane [GO:0031226]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; phosphatidylinositol 3-kinase binding [GO:0043548]; platelet activating factor receptor activity [GO:0004992]; platelet-derived growth factor beta-receptor activity [GO:0005019]; platelet-derived growth factor binding [GO:0048407]; platelet-derived growth factor receptor binding [GO:0005161]; platelet-derived growth factor-activated receptor activity [GO:0005017]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; aging [GO:0007568]; aorta morphogenesis [GO:0035909]; cardiac myofibril assembly [GO:0055003]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell migration involved in coronary angiogenesis [GO:0060981]; cell migration involved in vasculogenesis [GO:0035441]; glycosaminoglycan biosynthetic process [GO:0006024]; hematopoietic progenitor cell differentiation [GO:0002244]; inner ear development [GO:0048839]; lung growth [GO:0060437]; male gonad development [GO:0008584]; MAPK cascade [GO:0000165]; metanephric comma-shaped body morphogenesis [GO:0072278]; metanephric glomerular capillary formation [GO:0072277]; metanephric glomerular mesangial cell proliferation involved in metanephros development [GO:0072262]; metanephric mesenchymal cell migration [GO:0035789]; metanephric mesenchyme development [GO:0072075]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of chemotaxis [GO:0050921]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway [GO:0035793]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein autophosphorylation [GO:0046777]; regulation of actin cytoskeleton organization [GO:0032956]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to fluid shear stress [GO:0034405]; response to hydrogen peroxide [GO:0042542]; response to hyperoxia [GO:0055093]; response to retinoic acid [GO:0032526]; retina vasculature development in camera-type eye [GO:0061298]; signal transduction [GO:0007165]; smooth muscle cell chemotaxis [GO:0071670]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	aging [GO:0007568]; aorta morphogenesis [GO:0035909]; cardiac myofibril assembly [GO:0055003]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell migration involved in coronary angiogenesis [GO:0060981]; cell migration involved in vasculogenesis [GO:0035441]; glycosaminoglycan biosynthetic process [GO:0006024]; hematopoietic progenitor cell differentiation [GO:0002244]; inner ear development [GO:0048839]; lung growth [GO:0060437]; male gonad development [GO:0008584]; MAPK cascade [GO:0000165]; metanephric comma-shaped body morphogenesis [GO:0072278]; metanephric glomerular capillary formation [GO:0072277]; metanephric glomerular mesangial cell proliferation involved in metanephros development [GO:0072262]; metanephric mesenchymal cell migration [GO:0035789]; metanephric mesenchyme development [GO:0072075]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol metabolic process [GO:0046488]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of chemotaxis [GO:0050921]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway [GO:0035793]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein autophosphorylation [GO:0046777]; regulation of actin cytoskeleton organization [GO:0032956]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to fluid shear stress [GO:0034405]; response to hydrogen peroxide [GO:0042542]; response to hyperoxia [GO:0055093]; response to retinoic acid [GO:0032526]; retina vasculature development in camera-type eye [GO:0061298]; signal transduction [GO:0007165]; smooth muscle cell chemotaxis [GO:0071670]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; intrinsic component of plasma membrane [GO:0031226]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]	ATP binding [GO:0005524]; enzyme binding [GO:0019899]; phosphatidylinositol 3-kinase binding [GO:0043548]; platelet activating factor receptor activity [GO:0004992]; platelet-derived growth factor-activated receptor activity [GO:0005017]; platelet-derived growth factor beta-receptor activity [GO:0005019]; platelet-derived growth factor binding [GO:0048407]; platelet-derived growth factor receptor binding [GO:0005161]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]
d1cwna__d3o3ra___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; glucuronolactone reductase activity [GO:0047941]; L-glucuronate reductase activity [GO:0047939]; mevaldate reductase (NADPH) activity [GO:0019726]; oxidoreductase activity [GO:0016491]; aldehyde catabolic process [GO:0046185]; cellular detoxification of aldehyde [GO:0110095]; D-glucuronate catabolic process [GO:0042840]; L-ascorbic acid biosynthetic process [GO:0019853]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; oxidoreductase activity [GO:0016491]	aldehyde catabolic process [GO:0046185]; cellular detoxification of aldehyde [GO:0110095]; D-glucuronate catabolic process [GO:0042840]; L-ascorbic acid biosynthetic process [GO:0019853]		apical plasma membrane [GO:0016324]; cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; glucuronolactone reductase activity [GO:0047941]; L-glucuronate reductase activity [GO:0047939]; mevaldate reductase (NADPH) activity [GO:0019726]; oxidoreductase activity [GO:0016491]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; oxidoreductase activity [GO:0016491]
d1cwpc__d1bev1___1					T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1cwpc__d1yc6h___1					T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]			T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1cwsa__d5wqjb1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; synapse [GO:0045202]; 3-mercaptopyruvate sulfurtransferase activity [GO:0016784]; identical protein binding [GO:0042802]; thiosulfate sulfurtransferase activity [GO:0004792]; hydrogen sulfide biosynthetic process [GO:0070814]; kidney development [GO:0001822]; liver development [GO:0001889]; spinal cord development [GO:0021510]; transsulfuration [GO:0019346]	cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	hydrogen sulfide biosynthetic process [GO:0070814]; kidney development [GO:0001822]; liver development [GO:0001889]; spinal cord development [GO:0021510]; transsulfuration [GO:0019346]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; synapse [GO:0045202]	phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]	3-mercaptopyruvate sulfurtransferase activity [GO:0016784]; identical protein binding [GO:0042802]; thiosulfate sulfurtransferase activity [GO:0004792]
d1cwua__d3d5qb2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid biosynthetic process [GO:0006633]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	fatty acid biosynthetic process [GO:0006633]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	chloroplast [GO:0009507]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d1cwub__d3pgxd___1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast [GO:0009507]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid biosynthetic process [GO:0006633]	oxidoreductase activity [GO:0016491]	fatty acid biosynthetic process [GO:0006633]		chloroplast [GO:0009507]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]	oxidoreductase activity [GO:0016491]
d1cwva3_d2zqka1__1			Proteobacteria	Proteobacteria	cell surface [GO:0009986]; cell adhesion [GO:0007155]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell surface [GO:0009986]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]		
d1cwva4_d1f02i2__1			Proteobacteria	Proteobacteria	cell surface [GO:0009986]; cell adhesion [GO:0007155]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell surface [GO:0009986]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]		
d1cwva5_d1e5ui2__1			Proteobacteria	Proteobacteria	cell surface [GO:0009986]; cell adhesion [GO:0007155]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell surface [GO:0009986]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]		
d1cwwa1_d1d2za___1	Metazoa	Metazoa	Chordata	Arthropoda	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d1cwya__d1jywa5__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]	beta-galactosidase complex [GO:0009341]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1cx1a1_d4duvb1__1			Actinobacteria	Proteobacteria	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	cellulase activity [GO:0008810]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1cx2b1_d1cvub1__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1cx2c1_d1ht8b1__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1cx2d1_d5ciga___1	Metazoa	Fungi	Chordata	Ascomycota	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1cx8g2_d1z8la2__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; HFE-transferrin receptor complex [GO:1990712]; integral component of plasma membrane [GO:0005887]; melanosome [GO:0042470]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transferrin receptor activity [GO:0004998]; virus receptor activity [GO:0001618]; cellular iron ion homeostasis [GO:0006879]; cellular response to drug [GO:0035690]; cellular response to leukemia inhibitory factor [GO:1990830]; iron ion transport [GO:0006826]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of bone resorption [GO:0045780]; positive regulation of isotype switching [GO:0045830]; positive regulation of T cell proliferation [GO:0042102]; receptor internalization [GO:0031623]; transferrin transport [GO:0033572]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; Ac-Asp-Glu binding [GO:1904492]; carboxypeptidase activity [GO:0004180]; dipeptidase activity [GO:0016805]; metal ion binding [GO:0046872]; metallocarboxypeptidase activity [GO:0004181]; peptidase activity [GO:0008233]; tetrahydrofolyl-poly(glutamate) polymer binding [GO:1904493]; C-terminal protein deglutamylation [GO:0035609]; cellular amino acid biosynthetic process [GO:0008652]; folic acid-containing compound metabolic process [GO:0006760]; proteolysis [GO:0006508]	cellular iron ion homeostasis [GO:0006879]; cellular response to drug [GO:0035690]; cellular response to leukemia inhibitory factor [GO:1990830]; iron ion transport [GO:0006826]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of bone resorption [GO:0045780]; positive regulation of isotype switching [GO:0045830]; positive regulation of T cell proliferation [GO:0042102]; receptor internalization [GO:0031623]; transferrin transport [GO:0033572]	cellular amino acid biosynthetic process [GO:0008652]; C-terminal protein deglutamylation [GO:0035609]; folic acid-containing compound metabolic process [GO:0006760]; proteolysis [GO:0006508]	basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; HFE-transferrin receptor complex [GO:1990712]; integral component of plasma membrane [GO:0005887]; melanosome [GO:0042470]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transferrin receptor activity [GO:0004998]; virus receptor activity [GO:0001618]	Ac-Asp-Glu binding [GO:1904492]; carboxypeptidase activity [GO:0004180]; dipeptidase activity [GO:0016805]; metal ion binding [GO:0046872]; metallocarboxypeptidase activity [GO:0004181]; peptidase activity [GO:0008233]; tetrahydrofolyl-poly(glutamate) polymer binding [GO:1904493]
d1cxaa__d2mhma___1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	photosynthesis [GO:0015979]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	periplasmic space [GO:0042597]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1cxea2_d2j73b___1			Firmicutes	Thermotogae	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]
d1cxfa1_d3t5ia___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	carbohydrate metabolic process [GO:0005975]	response to stimulus [GO:0050896]; visual perception [GO:0007601]	extracellular region [GO:0005576]	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]
d1cxha3_d5ihra2__1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]; carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]
d1cxha4_d1vepa2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1cxia2_d1j18a1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1cxia3_d2f2hd3__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1cxka1_d1ayrb2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]; G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	carbohydrate metabolic process [GO:0005975]	G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	extracellular region [GO:0005576]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]
d1cxka2_d1ciua2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1cxla1_d1ayrc2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]; G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	carbohydrate metabolic process [GO:0005975]	G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	extracellular region [GO:0005576]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]
d1cxla2_d1peza2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1cxp.2_d2euna2__1	Metazoa	Fungi	Chordata	Ascomycota	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]; chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1cxya__d1x3xa___1		Metazoa	Proteobacteria	Nematoda (roundworms)	metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	metal ion binding [GO:0046872]	oxidation-reduction process [GO:0055114]				metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1cyda__d1xr3a1__1	Metazoa		Chordata	Actinobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NADP+) activity [GO:0050038]; protein self-association [GO:0043621]; glucose metabolic process [GO:0006006]; NADH oxidation [GO:0006116]; xylulose metabolic process [GO:0005997]	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]	glucose metabolic process [GO:0006006]; NADH oxidation [GO:0006116]; xylulose metabolic process [GO:0005997]	antibiotic biosynthetic process [GO:0017000]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NADP+) activity [GO:0050038]; protein self-association [GO:0043621]	oxidoreductase activity [GO:0016491]
d1cydb__d3k96a1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NADP+) activity [GO:0050038]; protein self-association [GO:0043621]; glucose metabolic process [GO:0006006]; NADH oxidation [GO:0006116]; xylulose metabolic process [GO:0005997]	cytosol [GO:0005829]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycerol-3-phosphate dehydrogenase [NAD(P)+] activity [GO:0047952]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophospholipid biosynthetic process [GO:0046474]	glucose metabolic process [GO:0006006]; NADH oxidation [GO:0006116]; xylulose metabolic process [GO:0005997]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophospholipid biosynthetic process [GO:0046474]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]	carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NADP+) activity [GO:0050038]; protein self-association [GO:0043621]	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity [GO:0047952]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]
d1cydd__d5uaxa1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NADP+) activity [GO:0050038]; protein self-association [GO:0043621]; glucose metabolic process [GO:0006006]; NADH oxidation [GO:0006116]; xylulose metabolic process [GO:0005997]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	glucose metabolic process [GO:0006006]; NADH oxidation [GO:0006116]; xylulose metabolic process [GO:0005997]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NADP+) activity [GO:0050038]; protein self-association [GO:0043621]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1cyga1_d4yeed___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]	carbohydrate metabolic process [GO:0005975]	fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]
d1cyga4_d1expa___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]
d1cyua__d4n6v3___1	Metazoa	Metazoa	Chordata	Chordata	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; protease binding [GO:0002020]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]	cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	adult locomotory behavior [GO:0008344]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; protease binding [GO:0002020]; RNA binding [GO:0003723]
d1cyva__d2bo9b2__1	Metazoa	Metazoa	Chordata	Chordata	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; histone acetylation [GO:0016573]; proteolysis [GO:0006508]	cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	histone acetylation [GO:0016573]; proteolysis [GO:0006508]	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	extracellular space [GO:0005615]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1cz0a__d1evwb___1					endonuclease activity [GO:0004519]; intron homing [GO:0006314]	endonuclease activity [GO:0004519]; intron homing [GO:0006314]	intron homing [GO:0006314]	intron homing [GO:0006314]			endonuclease activity [GO:0004519]	endonuclease activity [GO:0004519]
d1cz1a__d2cnca1__1	Fungi		Ascomycota	Proteobacteria	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]; cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	xylan catabolic process [GO:0045493]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]		cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]	endo-1,4-beta-xylanase activity [GO:0031176]
d1cz3a__d1ly3a___1		Fungi	Thermotogae	Ascomycota	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d1cz3b__d5eccb___1			Thermotogae	Proteobacteria	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1cz5a1_d1y4za1__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; hydrolase activity [GO:0016787]	integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; hydrolase activity [GO:0016787]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]
d1cz8h1_d2q7yb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1cz8l1_d1mcwm1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	antigen binding [GO:0003823]
d1cz8l1_d4kk6d1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1cz8l2_d1hxmh1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	transmembrane signaling receptor activity [GO:0004888]
d1cz8l2_d3o3ad2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1cz8x1_d4gq9l2__1	Metazoa		Chordata		cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	
d1cz8y1_d2nxyc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1czan1_d1j6za2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d1czan1_d1qhab4__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1czan4_d4fpaa3__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1czda1_d3k4xa6__1		Fungi		Ascomycota	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]		nucleus [GO:0005634]		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d1czda2_d1vpka1__1				Thermotogae	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA strand elongation involved in DNA replication [GO:0006271]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA strand elongation involved in DNA replication [GO:0006271]		cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]		3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1czdb1_d1jqja1__1				Proteobacteria	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]		3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1czdb2_d1b77c1__1					bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]				
d1czdb2_d1ok7a3__1				Proteobacteria	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]		3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1czfa__d1nhcf___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	polygalacturonase activity [GO:0004650]
d1czfa__d1o8fa___1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]
d1czfb__d1kcca___1	Fungi	Fungi	Ascomycota	Basidiomycota	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	polygalacturonase activity [GO:0004650]
d1czga__d1fnvd1__1				Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1czge__d4fnfc___1				Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1czha__d3owxa___1		Metazoa	Cyanobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1czie__d2wl0b___1	Metazoa		Chordata		aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1czka__d1xi2b___1		Metazoa	Cyanobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1czna__d4xdhb___1		Metazoa	Cyanobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1czpb__d3aebb1__1		Metazoa	Cyanobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]		mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]		mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1czsa__d1sddb4__1	Metazoa	Metazoa	Chordata	Chordata	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]	extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; copper ion binding [GO:0005507]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]	blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]	blood circulation [GO:0008015]; blood coagulation [GO:0007596]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]	copper ion binding [GO:0005507]	copper ion binding [GO:0005507]
d1czta__d4lk7c___1	Metazoa		Chordata	Proteobacteria	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]	carbohydrate binding [GO:0030246]
d1czvb__d4duxc1__1	Metazoa		Chordata	Proteobacteria	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]	lactose catabolic process [GO:0005990]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	beta-galactosidase complex [GO:0009341]	copper ion binding [GO:0005507]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1czwe__d1i4ga1__1				Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]
d1czwg__d1lt6e___1				Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1czwh__d1ts4a1__1				Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1czza1_d5h9ma___1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; varicosity [GO:0043196]; antigen binding [GO:0003823]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; cellular calcium ion homeostasis [GO:0006874]; cellular response to erythropoietin [GO:0036018]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; inflammatory response [GO:0006954]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein kinase B signaling [GO:0043491]; protein-containing complex assembly [GO:0065003]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; response to cobalamin [GO:0033590]; response to interferon-gamma [GO:0034341]; response to peptide [GO:1901652]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; transcription corepressor activity [GO:0003714]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular protein catabolic process [GO:0044257]; cellular protein metabolic process [GO:0044267]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of netrin-activated signaling pathway [GO:1902842]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of circadian rhythm [GO:0042752]; regulation of protein ubiquitination [GO:0031396]; rhythmic process [GO:0048511]; small GTPase mediated signal transduction [GO:0007264]; ubiquitin-dependent protein catabolic process [GO:0006511]	B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; cellular calcium ion homeostasis [GO:0006874]; cellular response to erythropoietin [GO:0036018]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; inflammatory response [GO:0006954]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein-containing complex assembly [GO:0065003]; protein kinase B signaling [GO:0043491]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; response to cobalamin [GO:0033590]; response to interferon-gamma [GO:0034341]; response to peptide [GO:1901652]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular protein catabolic process [GO:0044257]; cellular protein metabolic process [GO:0044267]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of netrin-activated signaling pathway [GO:1902842]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of circadian rhythm [GO:0042752]; regulation of protein ubiquitination [GO:0031396]; rhythmic process [GO:0048511]; small GTPase mediated signal transduction [GO:0007264]; ubiquitin-dependent protein catabolic process [GO:0006511]	CD40 receptor complex [GO:0035631]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; varicosity [GO:0043196]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]	antigen binding [GO:0003823]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]	transcription corepressor activity [GO:0003714]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1d00f1_d5wzzb___1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; varicosity [GO:0043196]; antigen binding [GO:0003823]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; cellular calcium ion homeostasis [GO:0006874]; cellular response to erythropoietin [GO:0036018]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; inflammatory response [GO:0006954]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein kinase B signaling [GO:0043491]; protein-containing complex assembly [GO:0065003]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; response to cobalamin [GO:0033590]; response to interferon-gamma [GO:0034341]; response to peptide [GO:1901652]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	beta-catenin destruction complex [GO:0030877]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling adaptor activity [GO:0035591]; SMAD binding [GO:0046332]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular protein-containing complex assembly [GO:0034622]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of Wnt signaling pathway [GO:0030111]; Wnt signaling pathway [GO:0016055]	B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; cellular calcium ion homeostasis [GO:0006874]; cellular response to erythropoietin [GO:0036018]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; inflammatory response [GO:0006954]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein-containing complex assembly [GO:0065003]; protein kinase B signaling [GO:0043491]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; response to cobalamin [GO:0033590]; response to interferon-gamma [GO:0034341]; response to peptide [GO:1901652]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular protein-containing complex assembly [GO:0034622]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of Wnt signaling pathway [GO:0030111]; Wnt signaling pathway [GO:0016055]	CD40 receptor complex [GO:0035631]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; varicosity [GO:0043196]	beta-catenin destruction complex [GO:0030877]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	antigen binding [GO:0003823]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]	armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; I-SMAD binding [GO:0070411]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling adaptor activity [GO:0035591]; SMAD binding [GO:0046332]; ubiquitin protein ligase binding [GO:0031625]
d1d01d1_d1d00c1__1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	CD40 receptor complex [GO:0035631]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; varicosity [GO:0043196]; antigen binding [GO:0003823]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; cellular calcium ion homeostasis [GO:0006874]; cellular response to erythropoietin [GO:0036018]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; inflammatory response [GO:0006954]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein kinase B signaling [GO:0043491]; protein-containing complex assembly [GO:0065003]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; response to cobalamin [GO:0033590]; response to interferon-gamma [GO:0034341]; response to peptide [GO:1901652]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; cellular calcium ion homeostasis [GO:0006874]; cellular response to erythropoietin [GO:0036018]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; inflammatory response [GO:0006954]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein-containing complex assembly [GO:0065003]; protein kinase B signaling [GO:0043491]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; response to cobalamin [GO:0033590]; response to interferon-gamma [GO:0034341]; response to peptide [GO:1901652]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	CD40 receptor complex [GO:0035631]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; varicosity [GO:0043196]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]
d1d01d1_d1k2fb___1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	beta-catenin destruction complex [GO:0030877]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; SCF ubiquitin ligase complex [GO:0019005]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; post-embryonic development [GO:0009791]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; post-embryonic development [GO:0009791]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	beta-catenin destruction complex [GO:0030877]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; SCF ubiquitin ligase complex [GO:0019005]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1d01e1_d4k8uc___1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; WW domain binding [GO:0050699]; zinc ion binding [GO:0008270]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase activity [GO:0045860]; regulation of apoptotic process [GO:0042981]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323]; signal transduction [GO:0007165]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase activity [GO:0045860]; regulation of apoptotic process [GO:0042981]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323]; signal transduction [GO:0007165]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; WW domain binding [GO:0050699]; zinc ion binding [GO:0008270]
d1d03a__d1ycfa1__1			Cyanobacteria	Firmicutes	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1d03a__d3b6kb___1			Cyanobacteria	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; membrane [GO:0016020]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]		oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; membrane [GO:0016020]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1d04a__d1yoba1__1			Cyanobacteria	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]			electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1d04a__d3fjoa1__1		Metazoa	Cyanobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1d07a__d3g9xa1__1			Proteobacteria	Actinobacteria	periplasmic space [GO:0042597]; haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	response to toxic substance [GO:0009636]	response to toxic substance [GO:0009636]	periplasmic space [GO:0042597]		haloalkane dehalogenase activity [GO:0018786]	haloalkane dehalogenase activity [GO:0018786]
d1d09a1_d3e2pe2__1			Proteobacteria	Euryarchaeota	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]; zinc ion binding [GO:0008270]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1d09c1_d4eknb2__1			Proteobacteria	Euryarchaeota	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]; zinc ion binding [GO:0008270]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1d09c2_d3e2pd1__1			Proteobacteria	Euryarchaeota	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]; zinc ion binding [GO:0008270]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1d0aa1_d2an6a1__1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	beta-catenin destruction complex [GO:0030877]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; SCF ubiquitin ligase complex [GO:0019005]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; post-embryonic development [GO:0009791]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; post-embryonic development [GO:0009791]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	beta-catenin destruction complex [GO:0030877]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; SCF ubiquitin ligase complex [GO:0019005]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1d0ab1_d5h9mb___1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; transcription corepressor activity [GO:0003714]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular protein catabolic process [GO:0044257]; cellular protein metabolic process [GO:0044267]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of netrin-activated signaling pathway [GO:1902842]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of circadian rhythm [GO:0042752]; regulation of protein ubiquitination [GO:0031396]; rhythmic process [GO:0048511]; small GTPase mediated signal transduction [GO:0007264]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular protein catabolic process [GO:0044257]; cellular protein metabolic process [GO:0044267]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of netrin-activated signaling pathway [GO:1902842]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of circadian rhythm [GO:0042752]; regulation of protein ubiquitination [GO:0031396]; rhythmic process [GO:0048511]; small GTPase mediated signal transduction [GO:0007264]; ubiquitin-dependent protein catabolic process [GO:0006511]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	transcription corepressor activity [GO:0003714]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1d0ac1_d1d0jf1__1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1d0ad1_d1kzza1__1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; deubiquitinase activator activity [GO:0035800]; metal ion binding [GO:0046872]; ubiquitin protein ligase binding [GO:0031625]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to interleukin-1 [GO:0071347]; cellular response to ionizing radiation [GO:0071479]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; positive regulation of protein deubiquitination [GO:1903003]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; proteolysis [GO:0006508]; signal transduction [GO:0007165]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to interleukin-1 [GO:0071347]; cellular response to ionizing radiation [GO:0071479]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; positive regulation of protein deubiquitination [GO:1903003]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; proteolysis [GO:0006508]; signal transduction [GO:0007165]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	deubiquitinase activator activity [GO:0035800]; metal ion binding [GO:0046872]; ubiquitin protein ligase binding [GO:0031625]
d1d0ad1_d5wzzd___1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	beta-catenin destruction complex [GO:0030877]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling adaptor activity [GO:0035591]; SMAD binding [GO:0046332]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular protein-containing complex assembly [GO:0034622]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of Wnt signaling pathway [GO:0030111]; Wnt signaling pathway [GO:0016055]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular protein-containing complex assembly [GO:0034622]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of Wnt signaling pathway [GO:0030111]; Wnt signaling pathway [GO:0016055]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	beta-catenin destruction complex [GO:0030877]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; I-SMAD binding [GO:0070411]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling adaptor activity [GO:0035591]; SMAD binding [GO:0046332]; ubiquitin protein ligase binding [GO:0031625]
d1d0ha1_d1w2tc1__1			Firmicutes	Thermotogae	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	negative regulation of neurotransmitter secretion [GO:0046929]	carbohydrate metabolic process [GO:0005975]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	beta-fructofuranosidase activity [GO:0004564]
d1d0ha2_d3azwa2__1			Firmicutes	Firmicutes	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]	negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]
d1d0ie__d3n86n___1			Actinobacteria	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]		cytosol [GO:0005829]	3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1d0ii__d5x47c___1			Actinobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1d0il__d3n8nu___1			Actinobacteria	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]		cytosol [GO:0005829]	3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1d0jc1_d4k8ua___1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; WW domain binding [GO:0050699]; zinc ion binding [GO:0008270]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase activity [GO:0045860]; regulation of apoptotic process [GO:0042981]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323]; signal transduction [GO:0007165]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase activity [GO:0045860]; regulation of apoptotic process [GO:0042981]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323]; signal transduction [GO:0007165]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; WW domain binding [GO:0050699]; zinc ion binding [GO:0008270]
d1d0na1_d1hqz1___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin filament binding [GO:0051015]; actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]	actin filament binding [GO:0051015]
d1d0na1_d3ffkd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d1d0na2_d2fghb5__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d1d0nb2_d1ak7a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]; actin filament severing [GO:0051014]; positive regulation of actin filament depolymerization [GO:0030836]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament depolymerization [GO:0030042]; actin filament severing [GO:0051014]; positive regulation of actin filament depolymerization [GO:0030836]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]	actin binding [GO:0003779]
d1d0nb4_d2fgha1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d1d1ia__d1jr0d___1				Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	toxin activity [GO:0090729]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d1d1jc__d1ypra___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; postsynapse [GO:0098794]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; actin binding [GO:0003779]; actin monomer binding [GO:0003785]; ATPase activity [GO:0016887]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; actin cytoskeleton organization [GO:0030036]; modification of postsynaptic actin cytoskeleton [GO:0098885]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ruffle assembly [GO:1900028]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of ATPase activity [GO:0032781]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of stress fiber assembly [GO:0051496]; protein stabilization [GO:0050821]; regulation of actin filament polymerization [GO:0030833]; regulation of synaptic vesicle exocytosis [GO:2000300]	cell [GO:0005623]; cell cortex [GO:0005938]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; actin monomer binding [GO:0003785]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; proline-rich region binding [GO:0070064]; intracellular transport [GO:0046907]; mitotic actomyosin contractile ring assembly [GO:1903475]; positive regulation of formin-nucleated actin cable assembly [GO:0090338]; sequestering of actin monomers [GO:0042989]	actin cytoskeleton organization [GO:0030036]; modification of postsynaptic actin cytoskeleton [GO:0098885]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ruffle assembly [GO:1900028]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of ATPase activity [GO:0032781]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of stress fiber assembly [GO:0051496]; protein stabilization [GO:0050821]; regulation of actin filament polymerization [GO:0030833]; regulation of synaptic vesicle exocytosis [GO:2000300]	intracellular transport [GO:0046907]; mitotic actomyosin contractile ring assembly [GO:1903475]; positive regulation of formin-nucleated actin cable assembly [GO:0090338]; sequestering of actin monomers [GO:0042989]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; postsynapse [GO:0098794]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]	cell [GO:0005623]; cell cortex [GO:0005938]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]	actin binding [GO:0003779]; actin monomer binding [GO:0003785]; ATPase activity [GO:0016887]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]	actin monomer binding [GO:0003785]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; proline-rich region binding [GO:0070064]
d1d1na__d5dszb2__1			Firmicutes	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation initiation factor activity [GO:0003743]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation initiation factor activity [GO:0003743]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1d1pb__d2wmyh___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; acid phosphatase activity [GO:0003993]; protein tyrosine phosphatase activity [GO:0004725]; protein dephosphorylation [GO:0006470]	protein tyrosine phosphatase activity [GO:0004725]	protein dephosphorylation [GO:0006470]		cytoplasm [GO:0005737]; nucleus [GO:0005634]		acid phosphatase activity [GO:0003993]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d1d1sb2_d3i3of___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; plasma membrane [GO:0005886]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; plasma membrane [GO:0005886]		alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1d1sc2_d1v3tb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; plasma membrane [GO:0005886]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; 13-prostaglandin reductase activity [GO:0036132]; 15-oxoprostaglandin 13-oxidase activity [GO:0047522]; 2-alkenal reductase [NAD(P)+] activity [GO:0032440]	ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	13-prostaglandin reductase activity [GO:0036132]; 15-oxoprostaglandin 13-oxidase activity [GO:0047522]; 2-alkenal reductase [NAD(P)+] activity [GO:0032440]
d1d1tb2_d1ks9a2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; plasma membrane [GO:0005886]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; 2-dehydropantoate 2-reductase activity [GO:0008677]; NADP binding [GO:0050661]; pantothenate biosynthetic process from valine [GO:0033317]	ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	pantothenate biosynthetic process from valine [GO:0033317]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	2-dehydropantoate 2-reductase activity [GO:0008677]; NADP binding [GO:0050661]
d1d1vb__d3e7gd___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; arginine catabolic process [GO:0006527]; blood coagulation [GO:0007596]; cellular response to laminar fluid shear stress [GO:0071499]; mitochondrion organization [GO:0007005]; negative regulation of blood pressure [GO:0045776]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; positive regulation of guanylate cyclase activity [GO:0031284]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; arginine binding [GO:0034618]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin binding [GO:0034617]; arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; circadian rhythm [GO:0007623]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of leukocyte mediated cytotoxicity [GO:0001912]; prostaglandin secretion [GO:0032310]; protein targeting to peroxisome [GO:0006625]; regulation of cell population proliferation [GO:0042127]; regulation of cellular respiration [GO:0043457]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	arginine catabolic process [GO:0006527]; blood coagulation [GO:0007596]; cellular response to laminar fluid shear stress [GO:0071499]; mitochondrion organization [GO:0007005]; negative regulation of blood pressure [GO:0045776]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; positive regulation of guanylate cyclase activity [GO:0031284]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496]	arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; circadian rhythm [GO:0007623]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of leukocyte mediated cytotoxicity [GO:0001912]; prostaglandin secretion [GO:0032310]; protein targeting to peroxisome [GO:0006625]; regulation of cell population proliferation [GO:0042127]; regulation of cellular respiration [GO:0043457]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	caveola [GO:0005901]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]	arginine binding [GO:0034618]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin binding [GO:0034617]
d1d1wa__d5g6oa___1	Metazoa		Chordata	Firmicutes	caveola [GO:0005901]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; arginine catabolic process [GO:0006527]; blood coagulation [GO:0007596]; cellular response to laminar fluid shear stress [GO:0071499]; mitochondrion organization [GO:0007005]; negative regulation of blood pressure [GO:0045776]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; positive regulation of guanylate cyclase activity [GO:0031284]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric-oxide synthase activity [GO:0004517]; nitric oxide biosynthetic process [GO:0006809]	arginine catabolic process [GO:0006527]; blood coagulation [GO:0007596]; cellular response to laminar fluid shear stress [GO:0071499]; mitochondrion organization [GO:0007005]; negative regulation of blood pressure [GO:0045776]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; positive regulation of guanylate cyclase activity [GO:0031284]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496]	nitric oxide biosynthetic process [GO:0006809]	caveola [GO:0005901]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]		calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric-oxide synthase activity [GO:0004517]
d1d1zc__d3vrqa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; SH3/SH2 adaptor activity [GO:0005070]; adaptive immune response [GO:0002250]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; regulation of immune response [GO:0050776]	membrane raft [GO:0045121]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]; cell surface receptor signaling pathway [GO:0007166]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of MAP kinase activity [GO:0043407]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	adaptive immune response [GO:0002250]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; regulation of immune response [GO:0050776]	cell surface receptor signaling pathway [GO:0007166]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of MAP kinase activity [GO:0043407]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	membrane raft [GO:0045121]; plasma membrane [GO:0005886]	SH3/SH2 adaptor activity [GO:0005070]	calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]
d1d2ab__d3rofa1__1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; nucleus [GO:0005634]; acid phosphatase activity [GO:0003993]; protein tyrosine phosphatase activity [GO:0004725]; protein dephosphorylation [GO:0006470]	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]	protein dephosphorylation [GO:0006470]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	extracellular region [GO:0005576]	acid phosphatase activity [GO:0003993]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d1d2ca__d3njrb1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	precorrin-6Y C5,15-methyltransferase (decarboxylating) activity [GO:0046025]; protein methyltransferase activity [GO:0008276]; cobalamin biosynthetic process [GO:0009236]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	cobalamin biosynthetic process [GO:0009236]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]		folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	precorrin-6Y C5,15-methyltransferase (decarboxylating) activity [GO:0046025]; protein methyltransferase activity [GO:0008276]
d1d2ea1_d3df2d1__1	Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]		mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	
d1d2ea2_d1ha3a2__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1d2eb2_d3wxme3__1	Metazoa		Chordata	Crenarchaeota	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1d2ec2_d3u6ba3__1	Metazoa		Chordata	Actinobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]	extracellular region [GO:0005576]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	
d1d2ed1_d2ey4d___1	Metazoa		Chordata	Euryarchaeota	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]	snoRNA binding [GO:0030515]; pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]	pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	snoRNA binding [GO:0030515]
d1d2hd__d1nbhc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]	folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d1d2oa1_d3phsa1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; peptidoglycan-based cell wall [GO:0009274]; collagen binding [GO:0005518]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	integral component of membrane [GO:0016021]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		extracellular region [GO:0005576]; peptidoglycan-based cell wall [GO:0009274]	integral component of membrane [GO:0016021]	collagen binding [GO:0005518]	
d1d2ra__d1vbma___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]; tRNA aminoacylation [GO:0043039]; tyrosyl-tRNA aminoacylation [GO:0006437]	tryptophanyl-tRNA aminoacylation [GO:0006436]	tRNA aminoacylation [GO:0043039]; tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]
d1d2ra__d5ts2e1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]; [citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	tryptophanyl-tRNA aminoacylation [GO:0006436]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	[citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1d2rf__d1x8xa___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]; tRNA aminoacylation [GO:0043039]; tyrosyl-tRNA aminoacylation [GO:0006437]	tryptophanyl-tRNA aminoacylation [GO:0006436]	tRNA aminoacylation [GO:0043039]; tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]
d1d2v.2_d1ub2a2__1	Metazoa		Chordata	Cyanobacteria	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]; chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]		chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1d2zb__d4rhwf___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d1d2zc1_d2gf5a2__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]
d1d2zc1_d3ezqe1__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]
d1d3ab1_d1pzfb1__1			Euryarchaeota	Apicomplexa	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]		L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d1d3ba__d1n9sn___1	Metazoa	Fungi	Chordata	Ascomycota	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]; enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]; histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]	mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]	poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]
d1d3bb__d1th7g2__1	Metazoa		Chordata	Crenarchaeota	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]; enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]; histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]		histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]		catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]		enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]	
d1d3bh__d1i4kc___1	Metazoa		Chordata	Euryarchaeota	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]; enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]; histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]		histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]		catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]		enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]	
d1d3bj__d4xq3f___1	Metazoa		Chordata	Crenarchaeota	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]; enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]; histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]	mRNA splicing, via spliceosome [GO:0000398]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]	small nucleolar ribonucleoprotein complex [GO:0005732]	enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]	
d1d3bk__d1lojb1__1	Metazoa		Chordata	Euryarchaeota	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]; enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]; histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]	mRNA splicing, via spliceosome [GO:0000398]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]	small nucleolar ribonucleoprotein complex [GO:0005732]	enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]	
d1d3bl__d1i81d___1	Metazoa		Chordata	Euryarchaeota	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]; enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]; histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]	mRNA splicing, via spliceosome [GO:0000398]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]	small nucleolar ribonucleoprotein complex [GO:0005732]	enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]	
d1d3bl__d4f7uf___1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]; enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]; histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; RNA binding [GO:0003723]; U1 snRNP binding [GO:1990446]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]	histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]	import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]	enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]	RNA binding [GO:0003723]; U1 snRNP binding [GO:1990446]
d1d3ca3_d1v3ka3__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1d3ca3_d4lq1a3__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	extracellular region [GO:0005576]	cytosol [GO:0005829]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1d3ca4_d1jz2c5__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1d3fa__d4z41a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1d3ua1_d1cdwa1__1		Metazoa	Euryarchaeota	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; male pronucleus [GO:0001940]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; transcriptional preinitiation complex [GO:0097550]; aryl hydrocarbon receptor binding [GO:0017162]; core promoter binding [GO:0001047]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; proximal promoter sequence-specific DNA binding [GO:0000987]; repressing transcription factor binding [GO:0070491]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II repressing transcription factor binding [GO:0001103]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIB-class transcription factor binding [GO:0001093]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; snRNA transcription by RNA polymerase II [GO:0042795]; spermatogenesis [GO:0007283]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	DNA-templated transcription, initiation [GO:0006352]	positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; spermatogenesis [GO:0007283]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]; viral process [GO:0016032]		cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; male pronucleus [GO:0001940]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional preinitiation complex [GO:0097550]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	aryl hydrocarbon receptor binding [GO:0017162]; core promoter binding [GO:0001047]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; proximal promoter sequence-specific DNA binding [GO:0000987]; repressing transcription factor binding [GO:0070491]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II repressing transcription factor binding [GO:0001103]; TFIIB-class transcription factor binding [GO:0001093]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1d3ua2_d3cwtb2__1			Euryarchaeota	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1d3va__d3ewfd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]
d1d3vb__d4cevf___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]
d1d4aa__d2m6sa___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	FMN binding [GO:0010181]; oxidation-reduction process [GO:0055114]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	FMN binding [GO:0010181]
d1d4ab__d4nlla___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1d4ad__d2ohig2__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1d4ha__d4h3ib___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d1d4ja__d5p4ja___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1d4na__d3t9va___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1d4p.1_d2ggvb___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; peptidase activity [GO:0008233]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive regulation of viral genome replication [GO:0045070]; RNA 5'-cap (guanine-N7)-methylation [GO:0106005]; RNA stabilization [GO:0043489]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive regulation of viral genome replication [GO:0045070]; RNA 5'-cap (guanine-N7)-methylation [GO:0106005]; RNA stabilization [GO:0043489]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	ATP binding [GO:0005524]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; peptidase activity [GO:0008233]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1d4sa__d3ec0b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1d4sa__d5p7ea___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1d4ta__d1fbva3__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; innate immune response [GO:0045087]; lymphocyte activation [GO:0046649]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative regulation of CD40 signaling pathway [GO:2000349]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; phagocytosis [GO:0006909]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle phase transition [GO:0044770]; cell population proliferation [GO:0008283]; cellular protein modification process [GO:0006464]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to steroid hormone stimulus [GO:0071383]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein K11-linked ubiquitination [GO:0070979]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; innate immune response [GO:0045087]; lymphocyte activation [GO:0046649]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative regulation of CD40 signaling pathway [GO:2000349]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; phagocytosis [GO:0006909]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]	cell cycle phase transition [GO:0044770]; cell population proliferation [GO:0008283]; cellular protein modification process [GO:0006464]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to steroid hormone stimulus [GO:0071383]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein K11-linked ubiquitination [GO:0070979]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]	ATP binding [GO:0005524]; enzyme binding [GO:0019899]; RNA binding [GO:0003723]; transcription coactivator activity [GO:0003713]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]; ubiquitin-protein transferase activity [GO:0004842]
d1d4ta__d1z3ka___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; innate immune response [GO:0045087]; lymphocyte activation [GO:0046649]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative regulation of CD40 signaling pathway [GO:2000349]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; phagocytosis [GO:0006909]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; postsynaptic density [GO:0014069]; vesicle membrane [GO:0012506]; cytoskeletal adaptor activity [GO:0008093]; phosphotyrosine residue binding [GO:0001784]; protein-containing complex binding [GO:0044877]; receptor signaling complex adaptor activity [GO:0030159]; scaffold protein binding [GO:0097110]; SH3/SH2 adaptor activity [GO:0005070]; actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; innate immune response [GO:0045087]; lymphocyte activation [GO:0046649]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative regulation of CD40 signaling pathway [GO:2000349]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; phagocytosis [GO:0006909]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]	actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; postsynaptic density [GO:0014069]; vesicle membrane [GO:0012506]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]	cytoskeletal adaptor activity [GO:0008093]; phosphotyrosine residue binding [GO:0001784]; protein-containing complex binding [GO:0044877]; receptor signaling complex adaptor activity [GO:0030159]; scaffold protein binding [GO:0097110]; SH3/SH2 adaptor activity [GO:0005070]
d1d4wb__d3n8ma___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; innate immune response [GO:0045087]; lymphocyte activation [GO:0046649]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative regulation of CD40 signaling pathway [GO:2000349]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; phagocytosis [GO:0006909]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; innate immune response [GO:0045087]; lymphocyte activation [GO:0046649]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative regulation of CD40 signaling pathway [GO:2000349]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; phagocytosis [GO:0006909]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]
d1d4xg__d1npha3__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; actin polymerization or depolymerization [GO:0008154]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; barbed-end actin filament capping [GO:0051016]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]; vesicle-mediated transport [GO:0016192]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; actin polymerization or depolymerization [GO:0008154]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; barbed-end actin filament capping [GO:0051016]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]; vesicle-mediated transport [GO:0016192]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1d4za__d3nhza___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; growth of symbiont in host [GO:0044117]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	growth of symbiont in host [GO:0044117]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]	cytosol [GO:0005829]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1d5aa1_d4du4a1__1			Crenarchaeota		DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]			DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1d5bb1_d5vcoc1__1	Metazoa	Metazoa	Chordata	Arthropoda	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cysteine-type peptidase activity [GO:0008234]
d1d5bh1_d1ydpb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1d5bh2_d5ks9a2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1d5bl2_d5x2ol1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; G protein-coupled receptor activity [GO:0004930]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	G protein-coupled receptor activity [GO:0004930]
d1d5fb__d5hpla___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; metal ion binding [GO:0046872]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; androgen receptor signaling pathway [GO:0030521]; brain development [GO:0007420]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; negative regulation of dendritic spine morphogenesis [GO:0061002]; ovarian follicle development [GO:0001541]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; prostate gland growth [GO:0060736]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; proteolysis [GO:0006508]; regulation of circadian rhythm [GO:0042752]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to cocaine [GO:0042220]; response to hydrogen peroxide [GO:0042542]; response to progesterone [GO:0032570]; rhythmic process [GO:0048511]; sperm entry [GO:0035037]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	androgen receptor signaling pathway [GO:0030521]; brain development [GO:0007420]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; negative regulation of dendritic spine morphogenesis [GO:0061002]; ovarian follicle development [GO:0001541]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; prostate gland growth [GO:0060736]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; proteolysis [GO:0006508]; regulation of circadian rhythm [GO:0042752]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to cocaine [GO:0042220]; response to hydrogen peroxide [GO:0042542]; response to progesterone [GO:0032570]; rhythmic process [GO:0048511]; sperm entry [GO:0035037]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; nucleus [GO:0005634]; proteasome complex [GO:0000502]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]	metal ion binding [GO:0046872]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]	protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d1d5ga__d2zlei1__1	Metazoa		Chordata	Proteobacteria	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1d5ih1_d4orzc___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]
d1d5l.1_d4p4qc___1	Metazoa	Fungi	Chordata	Ascomycota	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]; chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1d5l.2_d4fcna___1	Metazoa	Fungi	Chordata	Basidiomycota	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]; chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]	extracellular region [GO:0005576]	chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]
d1d5mb2_d1zsda2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1d5na1_d2w7wa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1d5na2_d2w7wb2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1d5nb1_d4gunh1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1d5nc1_d2awpa1__1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1d5nd1_d3ljfa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1d5ra2_d1g1ga___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; ubiquitin-specific protease binding [GO:1990381]; adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1d5xa1_d4m6ol1__1	Metazoa		Chordata		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	
d1d5xb2_d4p4ka1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	
d1d5za1_d4jo1m1__1	Metazoa		Chordata		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	viral envelope [GO:0019031]; virion membrane [GO:0055036]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	
d1d6ea2_d1zhbg2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1d6ea2_d4irsa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	
d1d6oa__d1bkfa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]
d1d6ob__d3uqia___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]		cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]		activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1d6ra__d3kqca___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1d6ub2_d1d6yb3__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	periplasmic space [GO:0042597]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d1d6vh2_d1agbb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1d6vl2_d3stlb1__1	Metazoa		Chordata	Actinobacteria	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	voltage-gated potassium channel complex [GO:0008076]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1d7bb__d1ulva3__1	Fungi		Basidiomycota	Actinobacteria	extracellular region [GO:0005576]; cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]; polysaccharide metabolic process [GO:0005976]	cellulose catabolic process [GO:0030245]	polysaccharide metabolic process [GO:0005976]	extracellular region [GO:0005576]		cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]
d1d7da__d1i8aa___1	Fungi		Basidiomycota	Thermotogae	extracellular region [GO:0005576]; cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d1d7db__d1pl3a___1	Fungi	Fungi	Basidiomycota	Basidiomycota	extracellular region [GO:0005576]; cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]	cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]
d1d7fa2_d2j72a___1			Firmicutes	Thermotogae	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]
d1d7fb4_d5mb2b1__1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	sucrose phosphorylase activity [GO:0009018]; cellular carbohydrate metabolic process [GO:0044262]	carbohydrate metabolic process [GO:0005975]	cellular carbohydrate metabolic process [GO:0044262]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	sucrose phosphorylase activity [GO:0009018]
d1d7ha__d3ihza___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]		cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]		activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1d7jb__d1q6ua___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	outer membrane-bounded periplasmic space [GO:0030288]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein refolding [GO:0042026]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	protein refolding [GO:0042026]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	outer membrane-bounded periplasmic space [GO:0030288]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1d7oa__d3etge2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid biosynthetic process [GO:0006633]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	fatty acid biosynthetic process [GO:0006633]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	chloroplast [GO:0009507]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1d7sa__d1v72a1__1			Proteobacteria	Proteobacteria	2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	metal ion binding [GO:0046872]; threonine aldolase activity [GO:0004793]; threonine catabolic process [GO:0006567]		threonine catabolic process [GO:0006567]			2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	metal ion binding [GO:0046872]; threonine aldolase activity [GO:0004793]
d1d7w.1_d4bm3a___1	Metazoa	Fungi	Chordata	Basidiomycota	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]; chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	response to oxidative stress [GO:0006979]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]		chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1d7xb__d4h82c___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1d8aa__d4bb5b___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytosol [GO:0005829]; membrane [GO:0016020]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d1d8ab__d4qeda___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]; membrane [GO:0016020]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1d8ea__d2h6fa1__1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]; protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]; protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]
d1d8ka__d5icca1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIE complex [GO:0005673]; DNA binding [GO:0003677]; RNA binding [GO:0003723]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	(RS)-norcoclaurine 6-O-methyltransferase activity [GO:0030786]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; alkaloid metabolic process [GO:0009820]	snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	alkaloid metabolic process [GO:0009820]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIE complex [GO:0005673]		DNA binding [GO:0003677]; RNA binding [GO:0003723]; RNA polymerase II general transcription initiation factor activity [GO:0016251]	(RS)-norcoclaurine 6-O-methyltransferase activity [GO:0030786]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]
d1d8mb__d4n4ee___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1d8ra__d3hj3c1__1												
d1d8tb1_d2zjpb1__1			Actinobacteria	Deinococcus-Thermus	extracellular region [GO:0005576]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	translation [GO:0006412]	extracellular region [GO:0005576]	cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d1d8tb2_d3cw2e3__1			Actinobacteria	Crenarchaeota	extracellular region [GO:0005576]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	extracellular region [GO:0005576]	cytosol [GO:0005829]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1d9bb2_d4ls7b2__1				Firmicutes		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1d9bb2_d4z8db1__1				Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1d9cb__d4x51b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]; adaptive immune response [GO:0002250]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of protein ADP-ribosylation [GO:0010835]	extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]; aging [GO:0007568]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; immune response [GO:0006955]; inflammatory response [GO:0006954]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of response to wounding [GO:1903034]; regulation of sensory perception of pain [GO:0051930]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]	adaptive immune response [GO:0002250]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of protein ADP-ribosylation [GO:0010835]	aging [GO:0007568]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; immune response [GO:0006955]; inflammatory response [GO:0006954]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of response to wounding [GO:1903034]; regulation of sensory perception of pain [GO:0051930]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]	cytokine activity [GO:0005125]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]
d1d9ga__d1higb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]; adaptive immune response [GO:0002250]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of protein ADP-ribosylation [GO:0010835]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular respiration [GO:1901857]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of iron ion import across plasma membrane [GO:1904440]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vitamin D biosynthetic process [GO:0060557]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein ADP-ribosylation [GO:0010835]; regulation of regulatory T cell differentiation [GO:0045589]; response to virus [GO:0009615]	adaptive immune response [GO:0002250]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of protein ADP-ribosylation [GO:0010835]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular respiration [GO:1901857]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of iron ion import across plasma membrane [GO:1904440]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vitamin D biosynthetic process [GO:0060557]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein ADP-ribosylation [GO:0010835]; regulation of regulatory T cell differentiation [GO:0045589]; response to virus [GO:0009615]	extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]	cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]
d1d9kb__d2gjja1__1	Metazoa		Chordata		T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]		T cell receptor complex [GO:0042101]			
d1d9kc1_d2xtjc___1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor recycling [GO:0001920]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	adaptive immune response [GO:0002250]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of receptor recycling [GO:0001920]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]		apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]
d1d9kc2_d1qo3a2__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	T cell receptor complex [GO:0042101]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1d9kd1_d2gitb2__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1d9ke__d1fc2d2__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1d9kf__d1hh9b1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1d9kh1_d3niff1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	adaptive immune response [GO:0002250]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1d9ub__d1hera___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lyase activity [GO:0016829]; lysozyme activity [GO:0003796]; lytic transglycosylase activity [GO:0008933]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lyase activity [GO:0016829]; lysozyme activity [GO:0003796]; lytic transglycosylase activity [GO:0008933]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1d9wa__d3wpja___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1daba__d2nspb___1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; periplasmic space [GO:0042597]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	cell outer membrane [GO:0009279]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]		aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]
d1daha__d3mwlb___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; ATP binding [GO:0005524]; dethiobiotin synthase activity [GO:0004141]; magnesium ion binding [GO:0000287]; biotin biosynthetic process [GO:0009102]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	biotin biosynthetic process [GO:0009102]		cytosol [GO:0005829]		ATP binding [GO:0005524]; dethiobiotin synthase activity [GO:0004141]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1daja__d2oipb1__1	Fungi		Ascomycota		dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	
d1dama__d2d2fa___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; ATP binding [GO:0005524]; dethiobiotin synthase activity [GO:0004141]; magnesium ion binding [GO:0000287]; biotin biosynthetic process [GO:0009102]	ATP binding [GO:0005524]; ATPase activity [GO:0016887]; metal ion binding [GO:0046872]	biotin biosynthetic process [GO:0009102]		cytosol [GO:0005829]		ATP binding [GO:0005524]; dethiobiotin synthase activity [GO:0004141]; magnesium ion binding [GO:0000287]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d1daoa2_d1n1pa2__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cholesterol metabolic process [GO:0008203]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	extracellular region [GO:0005576]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]
d1daob2_d1ng3b2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]; cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	cytoplasm [GO:0005737]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]
d1daod2_d1ryia2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]; cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	cytoplasm [GO:0005737]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]
d1daod2_d2c73b2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1daoe2_d1doea2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	benzoate catabolic process via hydroxylation [GO:0043640]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]		D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1dara1_d2qmua1__1			Deinococcus-Thermus	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1daya__d1a9ua___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; protein kinase CK2 complex [GO:0005956]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; regulation of cell cycle [GO:0051726]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; spindle pole [GO:0000922]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; MAP kinase activity [GO:0004707]; MAP kinase kinase activity [GO:0004708]; mitogen-activated protein kinase p38 binding [GO:0048273]; NFAT protein binding [GO:0051525]; protein phosphatase binding [GO:0019903]; protein serine/threonine kinase activity [GO:0004674]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cartilage condensation [GO:0001502]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; cellular response to ionizing radiation [GO:0071479]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; chondrocyte differentiation [GO:0002062]; DNA damage checkpoint [GO:0000077]; fatty acid oxidation [GO:0019395]; glucose metabolic process [GO:0006006]; intracellular signal transduction [GO:0035556]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neutrophil degranulation [GO:0043312]; osteoclast differentiation [GO:0030316]; p38MAPK cascade [GO:0038066]; peptidyl-serine phosphorylation [GO:0018105]; placenta development [GO:0001890]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cyclase activity [GO:0031281]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Ras protein signal transduction [GO:0007265]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of gene expression [GO:0010468]; regulation of ossification [GO:0030278]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of synaptic membrane adhesion [GO:0099179]; regulation of transcription by RNA polymerase II [GO:0006357]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; signal transduction in response to DNA damage [GO:0042770]; skeletal muscle tissue development [GO:0007519]; stress-induced premature senescence [GO:0090400]; striated muscle cell differentiation [GO:0051146]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; regulation of cell cycle [GO:0051726]	3'-UTR-mediated mRNA stabilization [GO:0070935]; activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cartilage condensation [GO:0001502]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; cellular response to ionizing radiation [GO:0071479]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; chondrocyte differentiation [GO:0002062]; DNA damage checkpoint [GO:0000077]; fatty acid oxidation [GO:0019395]; glucose metabolic process [GO:0006006]; intracellular signal transduction [GO:0035556]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neutrophil degranulation [GO:0043312]; osteoclast differentiation [GO:0030316]; p38MAPK cascade [GO:0038066]; peptidyl-serine phosphorylation [GO:0018105]; placenta development [GO:0001890]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cyclase activity [GO:0031281]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Ras protein signal transduction [GO:0007265]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of gene expression [GO:0010468]; regulation of ossification [GO:0030278]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of synaptic membrane adhesion [GO:0099179]; regulation of transcription by RNA polymerase II [GO:0006357]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; signal transduction in response to DNA damage [GO:0042770]; skeletal muscle tissue development [GO:0007519]; stress-induced premature senescence [GO:0090400]; striated muscle cell differentiation [GO:0051146]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cytosol [GO:0005829]; nucleus [GO:0005634]; protein kinase CK2 complex [GO:0005956]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; spindle pole [GO:0000922]	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; enzyme binding [GO:0019899]; MAP kinase activity [GO:0004707]; MAP kinase kinase activity [GO:0004708]; mitogen-activated protein kinase p38 binding [GO:0048273]; NFAT protein binding [GO:0051525]; protein phosphatase binding [GO:0019903]; protein serine/threonine kinase activity [GO:0004674]
d1db4a__d1zr8a___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]; antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]	extracellular region [GO:0005576]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1db8a3_d1rl3b1__1		Metazoa		Chordata		axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]		cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]		axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]		3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]
d1db8a4_d1stza1__1				Thermotogae		DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]		negative regulation of transcription, DNA-templated [GO:0045892]				DNA binding [GO:0003677]
d1dbah2_d2bsed1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	virus tail, baseplate [GO:0098025]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1dbah2_d4uujb2__1	Metazoa		Chordata	Actinobacteria	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	voltage-gated potassium channel complex [GO:0008076]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1dbal2_d5umnd1__1	Metazoa		Chordata	Negarnaviricota	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	host cell surface receptor binding [GO:0046789]
d1dbbh2_d3o2vl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1dbbl1_d3gswa2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1dbca3_d2fmyc1__1				Firmicutes		DNA binding [GO:0003677]; metal ion binding [GO:0046872]; regulation of transcription, DNA-templated [GO:0006355]		regulation of transcription, DNA-templated [GO:0006355]				DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d1dbca3_d3co2a___1				Proteobacteria		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]				integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]
d1dbfa__d3lmed1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		cytoplasm [GO:0005737]		chorismate mutase activity [GO:0004106]	
d1dbga__d1kcca___1		Fungi	Bacteroidetes	Basidiomycota	chondroitin B lyase activity [GO:0033999]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]		carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]		extracellular region [GO:0005576]	chondroitin B lyase activity [GO:0033999]	polygalacturonase activity [GO:0004650]
d1dbkh1_d3wyra1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; MHC class Ib receptor activity [GO:0032394]; transmembrane signaling receptor activity [GO:0004888]; cellular defense response [GO:0006968]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; positive regulation of cellular senescence [GO:2000774]; positive regulation of natural killer cell cytokine production [GO:0002729]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cellular defense response [GO:0006968]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; positive regulation of cellular senescence [GO:2000774]; positive regulation of natural killer cell cytokine production [GO:0002729]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class Ib receptor activity [GO:0032394]; transmembrane signaling receptor activity [GO:0004888]
d1dbkh2_d5vxlb___1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1dbkl2_d2qeja1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; monomeric IgA immunoglobulin complex [GO:0071748]; secretory dimeric IgA immunoglobulin complex [GO:0071752]; secretory IgA immunoglobulin complex [GO:0071751]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of respiratory burst [GO:0060267]; protein-chromophore linkage [GO:0018298]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	antibacterial humoral response [GO:0019731]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of respiratory burst [GO:0060267]; protein-chromophore linkage [GO:0018298]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; monomeric IgA immunoglobulin complex [GO:0071748]; secretory dimeric IgA immunoglobulin complex [GO:0071752]; secretory IgA immunoglobulin complex [GO:0071751]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1dbmh1_d4wnqa1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1dbna__d3pvnh___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1dbtb__d3ctle___1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytosol [GO:0005829]	cytosol [GO:0005829]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d1dbtc__d3g1fl___1			Firmicutes	Euryarchaeota	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]		orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1dbvp2_d2gd1q2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1dbwa__d1ffsa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d1dbwa__d2zaya___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	phosphorelay signal transduction system [GO:0000160]	nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	
d1dbya1_d3sbcc___1	Viridiplantae	Fungi	Chlorophyta	Ascomycota	cell [GO:0005623]; chloroplast [GO:0009507]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]; identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]; cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; chloroplast [GO:0009507]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]	protein disulfide oxidoreductase activity [GO:0015035]	identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]
d1dbya1_d4j56h1__1	Viridiplantae		Chlorophyta	Apicomplexa	cell [GO:0005623]; chloroplast [GO:0009507]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; chloroplast [GO:0009507]	cell [GO:0005623]; cytosol [GO:0005829]	protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d1dc3a2_d1nq5c2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1dc6b2_d1j0xq2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; GAIT complex [GO:0097452]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; microtubule cytoskeleton organization [GO:0000226]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; protein stabilization [GO:0050821]; regulation of translation [GO:0006417]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; microtubule cytoskeleton organization [GO:0000226]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; protein stabilization [GO:0050821]; regulation of translation [GO:0006417]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; GAIT complex [GO:0097452]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]
d1dc6b2_d1yl7f2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]
d1dc7a__d3eulc___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphorelay response regulator activity [GO:0000156]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; nitrogen fixation [GO:0009399]; regulation of nitrogen utilization [GO:0006808]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; regulation of nitrogen utilization [GO:0006808]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; phosphorelay response regulator activity [GO:0000156]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]
d1dc9a__d1znla___1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]
d1dcca__d1atjf___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]; vacuole [GO:0005773]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1dchb__d2ebba___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; identical protein binding [GO:0042802]; phenylalanine 4-monooxygenase activity [GO:0004505]; transcription coactivator activity [GO:0003713]; L-phenylalanine metabolic process [GO:0006558]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of protein binding [GO:0043393]; tetrahydrobiopterin biosynthetic process [GO:0006729]	4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; tetrahydrobiopterin biosynthetic process [GO:0006729]	L-phenylalanine metabolic process [GO:0006558]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of protein binding [GO:0043393]; tetrahydrobiopterin biosynthetic process [GO:0006729]	tetrahydrobiopterin biosynthetic process [GO:0006729]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; identical protein binding [GO:0042802]; phenylalanine 4-monooxygenase activity [GO:0004505]; transcription coactivator activity [GO:0003713]	4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]
d1dcic__d2a7sd2__1	Metazoa		Chordata	Actinobacteria	mitochondrion [GO:0005739]; peroxisome [GO:0005777]; delta3,5-delta2,4-dienoyl-CoA isomerase activity [GO:0051750]; fatty acid beta-oxidation [GO:0006635]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	fatty acid beta-oxidation [GO:0006635]	carbon fixation [GO:0015977]	mitochondrion [GO:0005739]; peroxisome [GO:0005777]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	delta3,5-delta2,4-dienoyl-CoA isomerase activity [GO:0051750]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]
d1dcka__d1ffwa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d1dcka__d2hqrb1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding [GO:0003677]
d1dckb__d3hv2a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	phosphorelay signal transduction system [GO:0000160]	nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	
d1dckb__d3rvoa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d1dcla1_d4w81a___1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]	
d1dcla2_d1fj1c1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1dcmb__d2chea___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]	DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	metal ion binding [GO:0046872]
d1dcoc__d3jstb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; identical protein binding [GO:0042802]; phenylalanine 4-monooxygenase activity [GO:0004505]; transcription coactivator activity [GO:0003713]; L-phenylalanine metabolic process [GO:0006558]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of protein binding [GO:0043393]; tetrahydrobiopterin biosynthetic process [GO:0006729]	4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; tetrahydrobiopterin biosynthetic process [GO:0006729]	L-phenylalanine metabolic process [GO:0006558]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of protein binding [GO:0043393]; tetrahydrobiopterin biosynthetic process [GO:0006729]	tetrahydrobiopterin biosynthetic process [GO:0006729]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; identical protein binding [GO:0042802]; phenylalanine 4-monooxygenase activity [GO:0004505]; transcription coactivator activity [GO:0003713]	4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]
d1dd8b1_d4ubud2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d1dd8c2_d4jaoa1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	polyketide synthase complex [GO:0034081]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	polyketide synthase complex [GO:0034081]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1dd8d1_d4jrhb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1ddfa1_d3ezql___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell surface [GO:0009986]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to amino acid starvation [GO:0034198]; cellular response to hyperoxia [GO:0071455]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway [GO:0097191]; Fas signaling pathway [GO:0036337]; immune response [GO:0006955]; necroptotic signaling pathway [GO:0097527]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of protein phosphorylation [GO:0001934]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of stress-activated MAPK cascade [GO:0032872]; signal transduction [GO:0007165]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to amino acid starvation [GO:0034198]; cellular response to hyperoxia [GO:0071455]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway [GO:0097191]; Fas signaling pathway [GO:0036337]; immune response [GO:0006955]; necroptotic signaling pathway [GO:0097527]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of protein phosphorylation [GO:0001934]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of stress-activated MAPK cascade [GO:0032872]; signal transduction [GO:0007165]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	CD95 death-inducing signaling complex [GO:0031265]; cell surface [GO:0009986]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]
d1ddga1_d5vw9a1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]		cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]	chloroplast [GO:0009507]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1ddga2_d3qe2b3__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1ddgb2_d1f20a2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]; ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]	ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]
d1ddha1_d1hxmf1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	transmembrane signaling receptor activity [GO:0004888]
d1ddha1_d1i7rb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ddja__d1o2va___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; other organism cell membrane [GO:0044218]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; Schaffer collateral - CA1 synapse [GO:0098685]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; kinase binding [GO:0019900]; proteasome core complex binding [GO:1904854]; protein antigen binding [GO:1990405]; protein domain specific binding [GO:0019904]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; extracellular matrix disassembly [GO:0022617]; fibrinolysis [GO:0042730]; interaction with symbiont [GO:0051702]; interaction with symbiont via secreted substance [GO:0052213]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of fibrinolysis [GO:0051918]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trophoblast giant cell differentiation [GO:0060707]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; extracellular matrix disassembly [GO:0022617]; fibrinolysis [GO:0042730]; interaction with symbiont [GO:0051702]; interaction with symbiont via secreted substance [GO:0052213]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of fibrinolysis [GO:0051918]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trophoblast giant cell differentiation [GO:0060707]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; other organism cell membrane [GO:0044218]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; Schaffer collateral - CA1 synapse [GO:0098685]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; kinase binding [GO:0019900]; proteasome core complex binding [GO:1904854]; protein antigen binding [GO:1990405]; protein domain specific binding [GO:0019904]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1ddlb__d1aym1___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ddoa2_d1l9da2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	cytoplasm [GO:0005737]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	sarcosine oxidase activity [GO:0008115]
d1ddod2_d1k0la2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	benzoate catabolic process via hydroxylation [GO:0043640]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]		D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1ddog2_d1l9db2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	cytoplasm [GO:0005737]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	sarcosine oxidase activity [GO:0008115]
d1ddog2_d2xfua2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1ddoh2_d1b37b2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]
d1ddsa__d4km0a1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]
d1ddva__d1maia___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; neuron projection [GO:0043005]; neuron spine [GO:0044309]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; G protein-coupled glutamate receptor binding [GO:0035256]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; protein heterodimerization activity [GO:0046982]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynapse [GO:0099186]; type 5 metabotropic glutamate receptor binding [GO:0031802]; circadian rhythm [GO:0007623]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; protein localization to synapse [GO:0035418]; protein tetramerization [GO:0051262]; regulation of dendritic spine maintenance [GO:1902950]; regulation of store-operated calcium entry [GO:2001256]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to cocaine [GO:0042220]; response to nicotine [GO:0035094]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	circadian rhythm [GO:0007623]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; protein localization to synapse [GO:0035418]; protein tetramerization [GO:0051262]; regulation of dendritic spine maintenance [GO:1902950]; regulation of store-operated calcium entry [GO:2001256]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to cocaine [GO:0042220]; response to nicotine [GO:0035094]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; neuron spine [GO:0044309]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	G protein-coupled glutamate receptor binding [GO:0035256]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; protein heterodimerization activity [GO:0046982]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynapse [GO:0099186]; type 5 metabotropic glutamate receptor binding [GO:0031802]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]
d1ddxb1_d5u5ua___1	Metazoa	Fungi	Chordata	Ascomycota	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	integral component of membrane [GO:0016021]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1ddxc1_d1pgeb1__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1de0b__d1kjwa2__1		Metazoa	Proteobacteria	Chordata	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	nitrogen fixation [GO:0009399]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	molybdenum-iron nitrogenase complex [GO:0016612]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]
d1de0b__d4wzah___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1de1a__d2ca8a2__1		Metazoa		Platyhelminthes	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]				electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione transferase activity [GO:0004364]
d1de4a1_d3mlwm2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1de4d1_d1um5l1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1de4f1_d2jbja1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; Ac-Asp-Glu binding [GO:1904492]; carboxypeptidase activity [GO:0004180]; dipeptidase activity [GO:0016805]; metal ion binding [GO:0046872]; metallocarboxypeptidase activity [GO:0004181]; peptidase activity [GO:0008233]; tetrahydrofolyl-poly(glutamate) polymer binding [GO:1904493]; C-terminal protein deglutamylation [GO:0035609]; cellular amino acid biosynthetic process [GO:0008652]; folic acid-containing compound metabolic process [GO:0006760]; proteolysis [GO:0006508]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cellular amino acid biosynthetic process [GO:0008652]; C-terminal protein deglutamylation [GO:0035609]; folic acid-containing compound metabolic process [GO:0006760]; proteolysis [GO:0006508]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	Ac-Asp-Glu binding [GO:1904492]; carboxypeptidase activity [GO:0004180]; dipeptidase activity [GO:0016805]; metal ion binding [GO:0046872]; metallocarboxypeptidase activity [GO:0004181]; peptidase activity [GO:0008233]; tetrahydrofolyl-poly(glutamate) polymer binding [GO:1904493]
d1de4g1_d2ny4c2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1de4g2_d1zgla2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1de4h__d4uaob1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1de5a__d1s5ma___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; L-rhamnose isomerase activity [GO:0008740]; manganese ion binding [GO:0030145]; rhamnose binding [GO:0033296]; zinc ion binding [GO:0008270]; L-lyxose metabolic process [GO:0019324]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	L-lyxose metabolic process [GO:0019324]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; L-rhamnose isomerase activity [GO:0008740]; manganese ion binding [GO:0030145]; rhamnose binding [GO:0033296]; zinc ion binding [GO:0008270]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1de5c__d1xleb___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; L-rhamnose isomerase activity [GO:0008740]; manganese ion binding [GO:0030145]; rhamnose binding [GO:0033296]; zinc ion binding [GO:0008270]; L-lyxose metabolic process [GO:0019324]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	L-lyxose metabolic process [GO:0019324]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; L-rhamnose isomerase activity [GO:0008740]; manganese ion binding [GO:0030145]; rhamnose binding [GO:0033296]; zinc ion binding [GO:0008270]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1de6a__d2xima___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; L-rhamnose isomerase activity [GO:0008740]; manganese ion binding [GO:0030145]; rhamnose binding [GO:0033296]; zinc ion binding [GO:0008270]; L-lyxose metabolic process [GO:0019324]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	L-lyxose metabolic process [GO:0019324]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; L-rhamnose isomerase activity [GO:0008740]; manganese ion binding [GO:0030145]; rhamnose binding [GO:0033296]; zinc ion binding [GO:0008270]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1de7.2_d3l3ta___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; tertiary granule lumen [GO:1904724]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; antimicrobial humoral response [GO:0019730]; cobalamin metabolic process [GO:0009235]; digestion [GO:0007586]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	antimicrobial humoral response [GO:0019730]; cobalamin metabolic process [GO:0009235]; digestion [GO:0007586]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; tertiary granule lumen [GO:1904724]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1de9b__d3g0rb___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	DNA repair [GO:0006281]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]		3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d1deda1_d1thda1__1			Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1deda2_d2j72b___1			Firmicutes	Thermotogae	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]
d1dedb1_d5e70d1__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	extracellular region [GO:0005576]	cytosol [GO:0005829]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1deeb1_d3a67l___1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	IgG binding [GO:0019864]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1deec1_d2yr3a1__1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]	actin cytoskeleton [GO:0015629]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; actin binding [GO:0003779]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; myosin light chain kinase activity [GO:0004687]; protein kinase activity [GO:0004672]; aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cardiovascular system development [GO:0072358]; cellular hypotonic response [GO:0071476]; muscle contraction [GO:0006936]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]	pathogenesis [GO:0009405]	aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cardiovascular system development [GO:0072358]; cellular hypotonic response [GO:0071476]; muscle contraction [GO:0006936]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	actin cytoskeleton [GO:0015629]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]	IgG binding [GO:0019864]	actin binding [GO:0003779]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; myosin light chain kinase activity [GO:0004687]; protein kinase activity [GO:0004672]
d1deec2_d5x2ql1__1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; G protein-coupled receptor activity [GO:0004930]	pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	IgG binding [GO:0019864]	G protein-coupled receptor activity [GO:0004930]
d1deed1_d5cckl1__1			Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]		IgG binding [GO:0019864]	
d1deed2_d2j6eh1__1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	pathogenesis [GO:0009405]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	IgG binding [GO:0019864]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1deef2_d2edka1__1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]	cytosol [GO:0005829]; myosin filament [GO:0032982]; actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	cytosol [GO:0005829]; myosin filament [GO:0032982]	IgG binding [GO:0019864]	actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]
d1deja2_d1mwka2__1	Metazoa		Chordata	Proteobacteria	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	identical protein binding [GO:0042802]; plasmid partitioning [GO:0030541]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	plasmid partitioning [GO:0030541]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]		actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	identical protein binding [GO:0042802]
d1dejs__d1p8xa1__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1dela__d2y8ea___1		Metazoa		Arthropoda	(deoxy)nucleoside-phosphate kinase activity [GO:0047507]; ATP binding [GO:0005524]	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; synapse [GO:0045202]; vesicle [GO:0031982]; actin binding [GO:0003779]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; axon guidance [GO:0007411]; compound eye morphogenesis [GO:0001745]; defense response to fungus [GO:0050832]; exocytosis [GO:0006887]; germarium-derived egg chamber formation [GO:0007293]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; oocyte microtubule cytoskeleton polarization [GO:0008103]; phototransduction [GO:0007602]; pole plasm oskar mRNA localization [GO:0045451]; R7 cell development [GO:0045467]; Rab protein signal transduction [GO:0032482]; regulation of postsynaptic membrane potential [GO:0060078]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192]		axon guidance [GO:0007411]; compound eye morphogenesis [GO:0001745]; defense response to fungus [GO:0050832]; exocytosis [GO:0006887]; germarium-derived egg chamber formation [GO:0007293]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; oocyte microtubule cytoskeleton polarization [GO:0008103]; phototransduction [GO:0007602]; pole plasm oskar mRNA localization [GO:0045451]; R7 cell development [GO:0045467]; Rab protein signal transduction [GO:0032482]; regulation of postsynaptic membrane potential [GO:0060078]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192]		cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; synapse [GO:0045202]; vesicle [GO:0031982]	(deoxy)nucleoside-phosphate kinase activity [GO:0047507]; ATP binding [GO:0005524]	actin binding [GO:0003779]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1deoa__d5tifa1__1	Fungi		Ascomycota	Proteobacteria	hydrolase activity [GO:0016787]	outer membrane-bounded periplasmic space [GO:0030288]; acyl-CoA hydrolase activity [GO:0047617]; arylesterase activity [GO:0004064]; identical protein binding [GO:0042802]; lysophospholipase activity [GO:0004622]; myristoyl-[acyl-carrier-protein] hydrolase activity [GO:0016295]; myristoyl-CoA hydrolase activity [GO:0102991]; oleoyl-[acyl-carrier-protein] hydrolase activity [GO:0004320]; palmitoyl-[acyl-carrier-protein] hydrolase activity [GO:0016296]; palmitoyl-CoA hydrolase activity [GO:0016290]; peptidase activity [GO:0008233]; phospholipase activity [GO:0004620]; lipid metabolic process [GO:0006629]		lipid metabolic process [GO:0006629]		outer membrane-bounded periplasmic space [GO:0030288]	hydrolase activity [GO:0016787]	acyl-CoA hydrolase activity [GO:0047617]; arylesterase activity [GO:0004064]; identical protein binding [GO:0042802]; lysophospholipase activity [GO:0004622]; myristoyl-[acyl-carrier-protein] hydrolase activity [GO:0016295]; myristoyl-CoA hydrolase activity [GO:0102991]; oleoyl-[acyl-carrier-protein] hydrolase activity [GO:0004320]; palmitoyl-[acyl-carrier-protein] hydrolase activity [GO:0016296]; palmitoyl-CoA hydrolase activity [GO:0016290]; peptidase activity [GO:0008233]; phospholipase activity [GO:0004620]
d1deva__d5jekb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; transforming growth factor beta receptor signaling pathway [GO:0007179]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	endocytosis [GO:0006897]; endosomal transport [GO:0016197]; transforming growth factor beta receptor signaling pathway [GO:0007179]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	1-phosphatidylinositol binding [GO:0005545]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]
d1dewb__d3g0ra___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	DNA repair [GO:0006281]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]		3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d1df7a__d4qlga___1			Actinobacteria		cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]	
d1df7a__d5uipa1__1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d1dfbh1_d5ovwl___1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; cobalamin binding [GO:0031419]; cobalamin transport [GO:0015889]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cobalamin transport [GO:0015889]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cobalamin binding [GO:0031419]
d1dfbl1_d5i1al1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1dfbl2_d1dfbl1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1dfha__d1x7hb___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	antibiotic biosynthetic process [GO:0017000]	cytosol [GO:0005829]; membrane [GO:0016020]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	oxidoreductase activity [GO:0016491]
d1dfha__d5bsgc1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	cell wall [GO:0005618]; nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]; L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]	cytosol [GO:0005829]; membrane [GO:0016020]	cell wall [GO:0005618]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1dfji__d1yrga___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; GTPase activator activity [GO:0005096]; positive regulation of protein export from nucleus [GO:0046827]		positive regulation of protein export from nucleus [GO:0046827]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	GTPase activator activity [GO:0005096]
d1dfob__d2vgva___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]; cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]
d1dfoc__d5vwoc___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]; cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]	ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]
d1dfod__d4y0hd1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]; cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	cytosol [GO:0005829]; membrane [GO:0016020]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]	(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]
d1dfqa1_d5tpca1__1			Firmicutes	Firmicutes	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1dfva__d5hz9c1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]
d1dfvb__d4azna1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; retinoic acid binding [GO:0001972]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; retinoic acid binding [GO:0001972]
d1dfxa1_d2ji2d1__1			Proteobacteria	Proteobacteria	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	removal of superoxide radicals [GO:0019430]	removal of superoxide radicals [GO:0019430]			iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d1dfxa1_d4bglc___1			Proteobacteria	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d1dg1g2_d4lbya3__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1dg1h3_d1z0ac___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; nucleus [GO:0005634]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; nucleus [GO:0005634]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1dg4a__d1dkya2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein refolding [GO:0042026]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein refolding [GO:0042026]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]
d1dg5a__d3srux___1			Actinobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d1dgag__d1cfyb___1		Fungi		Ascomycota		actin cortical patch [GO:0030479]; actin cytoskeleton [GO:0015629]; nuclear matrix [GO:0016363]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]		actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]		actin cortical patch [GO:0030479]; actin cytoskeleton [GO:0015629]; nuclear matrix [GO:0016363]; plasma membrane [GO:0005886]		actin filament binding [GO:0051015]
d1dgag__d3ffna2__1		Metazoa		Chordata		actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]		actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]		actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]		actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1dgda__d2vmra___1			Proteobacteria	Firmicutes	2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]		glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]		cytoplasm [GO:0005737]	2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]
d1dgkn3_d1qhab3__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1dgkn4_d1dgkn2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1dgla__d1slba___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]; apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]		apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]		extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]
d1dglb__d5glvb2__1	Viridiplantae	Metazoa	Streptophyta	Nematoda (roundworms)	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1dgqa__d3zqka___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d1dgr.1_d1uijb1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]	aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]	protein homotrimerization [GO:0070207]		protein-containing complex [GO:0032991]	aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]	identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]	nutrient reservoir activity [GO:0045735]
d1dgr.4_d3bald___1	Viridiplantae		Streptophyta	Proteobacteria	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]	acetylacetone-cleaving enzyme activity [GO:0033752]; metal ion binding [GO:0046872]	protein homotrimerization [GO:0070207]		protein-containing complex [GO:0032991]		identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]	acetylacetone-cleaving enzyme activity [GO:0033752]; metal ion binding [GO:0046872]
d1dgsa3_d3gb8b1__1		Metazoa	Deinococcus-Thermus	Chordata	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	annulate lamellae [GO:0005642]; Cajal body [GO:0015030]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; host cell [GO:0043657]; intracellular membrane-bounded organelle [GO:0043231]; kinetochore [GO:0000776]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; nuclear export signal receptor activity [GO:0005049]; protein domain specific binding [GO:0019904]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; intracellular transport of virus [GO:0075733]; mRNA transport [GO:0051028]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein localization to nucleus [GO:0034504]; regulation of centrosome duplication [GO:0010824]; regulation of mRNA stability [GO:0043488]; regulation of protein catabolic process [GO:0042176]; regulation of protein export from nucleus [GO:0046825]; response to drug [GO:0042493]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; ribosomal subunit export from nucleus [GO:0000054]; ribosome biogenesis [GO:0042254]; viral process [GO:0016032]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	intracellular transport of virus [GO:0075733]; mRNA transport [GO:0051028]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein localization to nucleus [GO:0034504]; regulation of centrosome duplication [GO:0010824]; regulation of mRNA stability [GO:0043488]; regulation of protein catabolic process [GO:0042176]; regulation of protein export from nucleus [GO:0046825]; response to drug [GO:0042493]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; ribosomal subunit export from nucleus [GO:0000054]; ribosome biogenesis [GO:0042254]; viral process [GO:0016032]		annulate lamellae [GO:0005642]; Cajal body [GO:0015030]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; host cell [GO:0043657]; intracellular membrane-bounded organelle [GO:0043231]; kinetochore [GO:0000776]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]	nuclear export signal receptor activity [GO:0005049]; protein domain specific binding [GO:0019904]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]
d1dgsb3_d4ufza___1			Deinococcus-Thermus	Proteobacteria	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; base-excision repair, DNA ligation [GO:0006288]; DNA replication [GO:0006260]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	base-excision repair, DNA ligation [GO:0006288]; DNA replication [GO:0006260]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]
d1dgta4_d1ckma2__1						GTP binding [GO:0005525]; mRNA guanylyltransferase activity [GO:0004484]; 7-methylguanosine mRNA capping [GO:0006370]		7-methylguanosine mRNA capping [GO:0006370]				GTP binding [GO:0005525]; mRNA guanylyltransferase activity [GO:0004484]
d1dgta4_d5fpra___1				Firmicutes		DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]		DNA repair [GO:0006281]; DNA replication [GO:0006260]				DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]
d1dgva__d3m0wh___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; filopodium tip [GO:0032433]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; calcium-dependent protein kinase inhibitor activity [GO:0008427]; ion channel binding [GO:0044325]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein membrane anchor [GO:0043495]; protein serine/threonine kinase inhibitor activity [GO:0030291]; Ras GTPase binding [GO:0017016]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to growth factor stimulus [GO:0071363]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; cytoplasmic microtubule organization [GO:0031122]; double-strand break repair [GO:0006302]; endomitotic cell cycle [GO:0007113]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; platelet formation [GO:0030220]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of male germ cell proliferation [GO:2000256]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of cell division [GO:0051302]; regulation of cell population proliferation [GO:0042127]; response to ischemia [GO:0002931]; spermatid development [GO:0007286]; thrombopoietin-mediated signaling pathway [GO:0038163]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to growth factor stimulus [GO:0071363]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; cytoplasmic microtubule organization [GO:0031122]; double-strand break repair [GO:0006302]; endomitotic cell cycle [GO:0007113]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; platelet formation [GO:0030220]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of male germ cell proliferation [GO:2000256]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of cell division [GO:0051302]; regulation of cell population proliferation [GO:0042127]; response to ischemia [GO:0002931]; spermatid development [GO:0007286]; thrombopoietin-mediated signaling pathway [GO:0038163]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; filopodium tip [GO:0032433]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; vesicle [GO:0031982]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium-dependent protein kinase inhibitor activity [GO:0008427]; calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein membrane anchor [GO:0043495]; protein serine/threonine kinase inhibitor activity [GO:0030291]; Ras GTPase binding [GO:0017016]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d1dgwa__d5vg3a___1	Viridiplantae		Streptophyta	Firmicutes	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]; oxalate decarboxylase activity [GO:0046564]; oxalate metabolic process [GO:0033609]	protein homotrimerization [GO:0070207]	oxalate metabolic process [GO:0033609]	protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]	metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]; oxalate decarboxylase activity [GO:0046564]
d1dhia__d4elgg1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1dhja__d3ro9a1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d1dhjb__d3qlzb1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d1dhka1_d3ueqa2__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	amylosucrase activity [GO:0047669]
d1dhma__d1f9fd1__1					host cell nucleus [GO:0042025]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]; host cytoskeleton [GO:0044163]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]	host cell nucleus [GO:0042025]; host cytoskeleton [GO:0044163]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]
d1dhra__d1ky5d1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; 6,7-dihydropteridine reductase activity [GO:0004155]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; cellular response to drug [GO:0035690]; L-phenylalanine catabolic process [GO:0006559]; liver development [GO:0001889]; response to aluminum ion [GO:0010044]; response to glucagon [GO:0033762]; response to lead ion [GO:0010288]; tetrahydrobiopterin biosynthetic process [GO:0006729]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	cellular response to drug [GO:0035690]; liver development [GO:0001889]; L-phenylalanine catabolic process [GO:0006559]; response to aluminum ion [GO:0010044]; response to glucagon [GO:0033762]; response to lead ion [GO:0010288]; tetrahydrobiopterin biosynthetic process [GO:0006729]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	6,7-dihydropteridine reductase activity [GO:0004155]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]
d1di0a__d1zise___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1di0d__d1rvvu___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1di4a__d1ip1a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1di4a__d1l17a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1diba2_d2yfgd1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity [GO:0004486]; 10-formyltetrahydrofolate biosynthetic process [GO:0009257]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; folic acid metabolic process [GO:0046655]; heart development [GO:0007507]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; one-carbon metabolic process [GO:0006730]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; serine family amino acid biosynthetic process [GO:0009070]; serine family amino acid metabolic process [GO:0009069]; somite development [GO:0061053]; tetrahydrofolate interconversion [GO:0035999]		10-formyltetrahydrofolate biosynthetic process [GO:0009257]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; folic acid metabolic process [GO:0046655]; heart development [GO:0007507]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; one-carbon metabolic process [GO:0006730]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; serine family amino acid biosynthetic process [GO:0009070]; serine family amino acid metabolic process [GO:0009069]; somite development [GO:0061053]; tetrahydrofolate interconversion [GO:0035999]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity [GO:0004486]	
d1dica__d1uk3b___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1diea__d4zb5a1__1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1difa__d1sbgb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1difa__d4y3la___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1diia2_d1n5xa6__1		Metazoa	Proteobacteria	Chordata	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1diia2_d2bvfb1__1			Proteobacteria	Actinobacteria	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]					FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]
d1diib2_d2vfua1__1			Proteobacteria	Actinobacteria	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	membrane [GO:0016020]; D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]				membrane [GO:0016020]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]
d1dika1_d1dxeb___1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]	cytoplasm [GO:0005737]; 2-dehydro-3-deoxyglucarate aldolase activity [GO:0008672]; aldehyde-lyase activity [GO:0016832]; carbon-carbon lyase activity [GO:0016830]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]; galactarate catabolic process [GO:0046392]; glucarate catabolic process [GO:0019394]	pyruvate metabolic process [GO:0006090]	D-glucarate catabolic process [GO:0042838]; galactarate catabolic process [GO:0046392]; glucarate catabolic process [GO:0019394]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]	2-dehydro-3-deoxyglucarate aldolase activity [GO:0008672]; aldehyde-lyase activity [GO:0016832]; carbon-carbon lyase activity [GO:0016830]; magnesium ion binding [GO:0000287]
d1diog__d1iwpm___1			Proteobacteria	Proteobacteria	propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; glycerol dehydratase activity [GO:0046405]					propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; glycerol dehydratase activity [GO:0046405]
d1diqb1_d2bvgc2__1			Proteobacteria	Actinobacteria	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]					FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]
d1diqb2_d1w1qa2__1		Viridiplantae	Proteobacteria	Streptophyta	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	extracellular space [GO:0005615]; cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]		cytokinin metabolic process [GO:0009690]		extracellular space [GO:0005615]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]
d1dira__d3t7ca___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; 6,7-dihydropteridine reductase activity [GO:0004155]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; cellular response to drug [GO:0035690]; L-phenylalanine catabolic process [GO:0006559]; liver development [GO:0001889]; response to aluminum ion [GO:0010044]; response to glucagon [GO:0033762]; response to lead ion [GO:0010288]; tetrahydrobiopterin biosynthetic process [GO:0006729]	(+)-trans-carveol dehydrogenase activity [GO:0033702]; nucleotide binding [GO:0000166]	cellular response to drug [GO:0035690]; liver development [GO:0001889]; L-phenylalanine catabolic process [GO:0006559]; response to aluminum ion [GO:0010044]; response to glucagon [GO:0033762]; response to lead ion [GO:0010288]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]		6,7-dihydropteridine reductase activity [GO:0004155]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]	(+)-trans-carveol dehydrogenase activity [GO:0033702]; nucleotide binding [GO:0000166]
d1diya1_d1d2v.2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]; chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1diza2_d1qncb2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1dizb2_d1ytbb2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]
d1dj0b__d1ze1c2__1			Proteobacteria	Thermotogae	pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]; tRNA pseudouridine synthesis [GO:0031119]	mitochondrion [GO:0005739]; pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]; mRNA pseudouridine synthesis [GO:1990481]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	tRNA pseudouridine synthesis [GO:0031119]	mRNA pseudouridine synthesis [GO:1990481]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]		mitochondrion [GO:0005739]	pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]	pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]
d1dj2a__d1de0a___1	Viridiplantae		Streptophyta	Proteobacteria	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; plastid [GO:0009536]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; 'de novo' AMP biosynthetic process [GO:0044208]; IMP metabolic process [GO:0046040]; response to cadmium ion [GO:0046686]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	'de novo' AMP biosynthetic process [GO:0044208]; IMP metabolic process [GO:0046040]; response to cadmium ion [GO:0046686]	nitrogen fixation [GO:0009399]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; plastid [GO:0009536]	molybdenum-iron nitrogenase complex [GO:0016612]	adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1dj3b__d5vp7f1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; cytoplasm [GO:0005737]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; 'de novo' AMP biosynthetic process [GO:0044208]; IMP metabolic process [GO:0046040]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]; actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	'de novo' AMP biosynthetic process [GO:0044208]; IMP metabolic process [GO:0046040]	actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	chloroplast [GO:0009507]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]	GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]
d1dj5a__d1cqeb1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1djga1_d3buob1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d1djga2_d2ncea___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; central nervous system neuron axonogenesis [GO:0021955]; establishment of protein localization [GO:0045184]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of heart contraction [GO:0045822]; negative regulation of translation [GO:0017148]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of dense core granule biogenesis [GO:2000707]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of platelet aggregation [GO:0090330]; regulation of receptor-mediated endocytosis [GO:0048259]; response to antibiotic [GO:0046677]; response to corticosterone [GO:0051412]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; central nervous system neuron axonogenesis [GO:0021955]; establishment of protein localization [GO:0045184]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of heart contraction [GO:0045822]; negative regulation of translation [GO:0017148]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of dense core granule biogenesis [GO:2000707]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of platelet aggregation [GO:0090330]; regulation of receptor-mediated endocytosis [GO:0048259]; response to antibiotic [GO:0046677]; response to corticosterone [GO:0051412]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]	ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270]
d1djhb1_d1wlzb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]	calcium ion binding [GO:0005509]
d1djhb1_d1xk4k___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1djia1_d1kk8c___1	Metazoa	Metazoa	Chordata	Mollusca	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]
d1djia2_d2ki6f___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1djib2_d1byna___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]
d1djma__d1f51e___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	kinase activity [GO:0016301]; metal ion binding [GO:0046872]
d1djna1_d2bx7a___1			Proteobacteria	Firmicutes	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d1djna1_d4jiqa___1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]					4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d1djnb1_d4a3ua___1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]					4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d1djoa__d5ot0b___1			Proteobacteria	Euryarchaeota	periplasmic space [GO:0042597]; asparaginase activity [GO:0004067]; glutamin-(asparagin-)ase activity [GO:0050417]; asparagine metabolic process [GO:0006528]	asparaginase activity [GO:0004067]; cellular amino acid metabolic process [GO:0006520]	asparagine metabolic process [GO:0006528]	cellular amino acid metabolic process [GO:0006520]	periplasmic space [GO:0042597]		asparaginase activity [GO:0004067]; glutamin-(asparagin-)ase activity [GO:0050417]	asparaginase activity [GO:0004067]
d1djrg__d1s5df___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]	toxin activity [GO:0090729]	galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]
d1djrh__d4o1ne1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; peptidase activity [GO:0008233]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	peptidase activity [GO:0008233]
d1djwa1_d3suia___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1djwb1_d4cfra___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell leading edge [GO:0031252]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin-dependent ATPase activity [GO:0030898]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]; actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell leading edge [GO:0031252]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]	actin binding [GO:0003779]; actin-dependent ATPase activity [GO:0030898]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]
d1dk2a__d2ihmb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; B cell differentiation [GO:0030183]; base-excision repair [GO:0006284]; DNA recombination [GO:0006310]; double-strand break repair via nonhomologous end joining [GO:0006303]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; B cell differentiation [GO:0030183]; DNA recombination [GO:0006310]; double-strand break repair via nonhomologous end joining [GO:0006303]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d1dk3a__d4i2ha1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1dkaa__d3b1dc___1			Proteobacteria	Firmicutes	2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]		biosynthetic process [GO:0009058]			2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]
d1dkdb__d1q3rd2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1dkea__d1cp0a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1dkha__d4jeth___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1dkja__d1l09a___1	Metazoa		Chordata		extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1dkma__d2p2za___1			Proteobacteria	Deinococcus-Thermus	outer membrane-bounded periplasmic space [GO:0030288]; 4-phytase activity [GO:0008707]; acid phosphatase activity [GO:0003993]; inositol phosphate phosphatase activity [GO:0052745]; nucleotidase activity [GO:0008252]; sugar-phosphatase activity [GO:0050308]; cellular response to anoxia [GO:0071454]; cellular response to phosphate starvation [GO:0016036]; dephosphorylation [GO:0016311]; myo-inositol hexakisphosphate dephosphorylation [GO:0033518]	catalytic activity [GO:0003824]	cellular response to anoxia [GO:0071454]; cellular response to phosphate starvation [GO:0016036]; dephosphorylation [GO:0016311]; myo-inositol hexakisphosphate dephosphorylation [GO:0033518]		outer membrane-bounded periplasmic space [GO:0030288]		4-phytase activity [GO:0008707]; acid phosphatase activity [GO:0003993]; inositol phosphate phosphatase activity [GO:0052745]; nucleotidase activity [GO:0008252]; sugar-phosphatase activity [GO:0050308]	catalytic activity [GO:0003824]
d1dkoa__d1nd5d___1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; 4-phytase activity [GO:0008707]; acid phosphatase activity [GO:0003993]; inositol phosphate phosphatase activity [GO:0052745]; nucleotidase activity [GO:0008252]; sugar-phosphatase activity [GO:0050308]; cellular response to anoxia [GO:0071454]; cellular response to phosphate starvation [GO:0016036]; dephosphorylation [GO:0016311]; myo-inositol hexakisphosphate dephosphorylation [GO:0033518]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]; adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	cellular response to anoxia [GO:0071454]; cellular response to phosphate starvation [GO:0016036]; dephosphorylation [GO:0016311]; myo-inositol hexakisphosphate dephosphorylation [GO:0033518]	adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	outer membrane-bounded periplasmic space [GO:0030288]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	4-phytase activity [GO:0008707]; acid phosphatase activity [GO:0003993]; inositol phosphate phosphatase activity [GO:0052745]; nucleotidase activity [GO:0008252]; sugar-phosphatase activity [GO:0050308]	5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]
d1dkpa__d1yjxg___1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; 4-phytase activity [GO:0008707]; acid phosphatase activity [GO:0003993]; inositol phosphate phosphatase activity [GO:0052745]; nucleotidase activity [GO:0008252]; sugar-phosphatase activity [GO:0050308]; cellular response to anoxia [GO:0071454]; cellular response to phosphate starvation [GO:0016036]; dephosphorylation [GO:0016311]; myo-inositol hexakisphosphate dephosphorylation [GO:0033518]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	cellular response to anoxia [GO:0071454]; cellular response to phosphate starvation [GO:0016036]; dephosphorylation [GO:0016311]; myo-inositol hexakisphosphate dephosphorylation [GO:0033518]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	4-phytase activity [GO:0008707]; acid phosphatase activity [GO:0003993]; inositol phosphate phosphatase activity [GO:0052745]; nucleotidase activity [GO:0008252]; sugar-phosphatase activity [GO:0050308]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]
d1dkub1_d1upua___1			Firmicutes	Apicomplexa	cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]		ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]
d1dkva4_d3kx1a___1		Metazoa		Chordata		endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]		autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]		endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d1dkwa__d4o50a___1					cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytosol [GO:0005829]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1dkyb2_d4jnfa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein refolding [GO:0042026]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein refolding [GO:0042026]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]
d1dl5a1_d1r18a1__1		Metazoa	Thermotogae	Arthropoda	cytoplasm [GO:0005737]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]; protein repair [GO:0030091]	cytoplasm [GO:0005737]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]; defense response to bacterium [GO:0042742]	protein repair [GO:0030091]	defense response to bacterium [GO:0042742]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]
d1dl5b1_d1kr5a___1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]; protein repair [GO:0030091]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; cadherin binding [GO:0045296]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]; protein methylation [GO:0006479]; protein repair [GO:0030091]	protein repair [GO:0030091]	protein methylation [GO:0006479]; protein repair [GO:0030091]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]	cadherin binding [GO:0045296]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]
d1dl7l__d1nfdd1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1dl7l__d6emjb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1dlab__d3b3dc___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; retinoid metabolic process [GO:0001523]	oxidoreductase activity [GO:0016491]	retinoid metabolic process [GO:0001523]		cytosol [GO:0005829]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	oxidoreductase activity [GO:0016491]
d1dlab__d3lnma___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; retinoid metabolic process [GO:0001523]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	retinoid metabolic process [GO:0001523]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	cytosol [GO:0005829]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]
d1dlca2_d1w99a2__1			Firmicutes	Firmicutes	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]			signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d1dlfh__d1yymq1__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	antigen binding [GO:0003823]	structural molecule activity [GO:0005198]
d1dlfl__d4imkd1__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		antigen binding [GO:0003823]	
d1dlha1_d5f3hh2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]; cell development [GO:0048468]; cellular response to dexamethasone stimulus [GO:0071549]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of kinase activity [GO:0033673]; negative regulation of muscle hypertrophy [GO:0014741]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast proliferation [GO:2000818]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; negative regulation of skeletal muscle tissue growth [GO:0048632]; ovulation cycle process [GO:0022602]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; response to electrical stimulus [GO:0051602]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to gravity [GO:0009629]; response to heat [GO:0009408]; response to muscle activity [GO:0014850]; response to testosterone [GO:0033574]; skeletal muscle atrophy [GO:0014732]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell development [GO:0048468]; cellular response to dexamethasone stimulus [GO:0071549]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of kinase activity [GO:0033673]; negative regulation of muscle hypertrophy [GO:0014741]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast proliferation [GO:2000818]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; negative regulation of skeletal muscle tissue growth [GO:0048632]; ovulation cycle process [GO:0022602]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; response to electrical stimulus [GO:0051602]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to gravity [GO:0009629]; response to heat [GO:0009408]; response to muscle activity [GO:0014850]; response to testosterone [GO:0033574]; skeletal muscle atrophy [GO:0014732]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]
d1dlhb2_d4p5mc1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d1dlhd1_d2eytd1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	
d1dlhd2_d4pjac1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1dlhe1_d3c5zg1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d1dlia1_d5je8a2__1			Firmicutes	Firmicutes	NAD binding [GO:0051287]; UDP-glucose 6-dehydrogenase activity [GO:0003979]; polysaccharide biosynthetic process [GO:0000271]; UDP-glucuronate biosynthetic process [GO:0006065]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	polysaccharide biosynthetic process [GO:0000271]; UDP-glucuronate biosynthetic process [GO:0006065]				NAD binding [GO:0051287]; UDP-glucose 6-dehydrogenase activity [GO:0003979]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1dlk.1_d2bdia___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	digestion [GO:0007586]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1dlla2_d3i2ab1__1		Viridiplantae	Firmicutes	Streptophyta	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	serine-type endopeptidase inhibitor activity [GO:0004867]	negative regulation of neurotransmitter secretion [GO:0046929]		clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1dlpa1_d1kj1a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta		carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]
d1dlpc1_d2d04e___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta		carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]
d1dlpe1_d3dzwb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta		carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]
d1dlpf1_d1bwup___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta		carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]
d1dlqa__d2bura___1			Proteobacteria	Proteobacteria	catechol 1,2-dioxygenase activity [GO:0018576]; ferric iron binding [GO:0008199]; beta-ketoadipate pathway [GO:0042952]; catechol-containing compound catabolic process [GO:0019614]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	beta-ketoadipate pathway [GO:0042952]; catechol-containing compound catabolic process [GO:0019614]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			catechol 1,2-dioxygenase activity [GO:0018576]; ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d1dlra__d1tdra___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d1dlua2_d2cdhb2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1dlua2_d4e1ld2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1dluc1_d2qx1b1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d1dlud2_d3h77a2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]; fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]
d1dlva1_d1dd8b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1dlvb2_d4ubta1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d1dlvc1_d2cdhc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1dlvc1_d3h78b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]; fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]
d1dlvd2_d4xl4b2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	acetyl-CoA C-acetyltransferase activity [GO:0003985]; N-acetylornithine carbamoyltransferase activity [GO:0043857]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]; N-acetylornithine carbamoyltransferase activity [GO:0043857]
d1dlwa__d2bkmb___1			Ciliophora	Firmicutes	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d1dlya__d3nfed___1	Viridiplantae	Metazoa	Chlorophyta	Chordata	chloroplast [GO:0009507]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			chloroplast [GO:0009507]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1dm0b__d1v1oa1__1			Proteobacteria	Firmicutes	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	negative regulation of translation [GO:0017148]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	
d1dm0c__d1s5dh___1			Proteobacteria	Proteobacteria	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; negative regulation of translation [GO:0017148]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	negative regulation of translation [GO:0017148]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]
d1dm0d__d3mfga1__1		Metazoa	Proteobacteria	Chordata	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; negative regulation of translation [GO:0017148]		negative regulation of translation [GO:0017148]				rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	
d1dm0e__d1l0yd1__1		Metazoa	Proteobacteria	Chordata	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; negative regulation of translation [GO:0017148]	integral component of membrane [GO:0016021]	negative regulation of translation [GO:0017148]			integral component of membrane [GO:0016021]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	
d1dm0e__d4fo2h___1			Proteobacteria	Proteobacteria	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	negative regulation of translation [GO:0017148]			extracellular region [GO:0005576]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1dm0h__d1qoht___1			Proteobacteria	Proteobacteria	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	negative regulation of translation [GO:0017148]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]		extracellular region [GO:0005576]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	
d1dm1a__d5ee4e___1	Metazoa	Metazoa	Mollusca	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1dm3b2_d5wx5d1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1dm3c2_d1u0ub2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	pinosylvin synthase activity [GO:0050198]
d1dm3d2_d4ubta2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d1dm5e__d1anwb___1	Metazoa	Metazoa	Cnidaria	Chordata	calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]		blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]
d1dmle1_d3aizc1__1				Crenarchaeota	host cell nucleus [GO:0042025]; DNA binding [GO:0003677]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	host cell nucleus [GO:0042025]		DNA binding [GO:0003677]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d1dmlg1_d2ijxb1__1				Crenarchaeota	host cell nucleus [GO:0042025]; DNA binding [GO:0003677]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	host cell nucleus [GO:0042025]	PCNA complex [GO:0043626]	DNA binding [GO:0003677]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d1dmna__d5ugia___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	steroid metabolic process [GO:0008202]	steroid metabolic process [GO:0008202]			steroid delta-isomerase activity [GO:0004769]	steroid delta-isomerase activity [GO:0004769]
d1dmoa__d1xfzr1__1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	calcium-mediated signaling [GO:0019722]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1dmra1_d1kqga1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	formate dehydrogenase complex [GO:0009326]; membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (cytochrome-c-553) activity [GO:0047111]; formate dehydrogenase (NAD+) activity [GO:0008863]; formate dehydrogenase (quinone) activity [GO:0036397]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; selenium binding [GO:0008430]; anaerobic respiration [GO:0009061]; formate oxidation [GO:0015944]		anaerobic respiration [GO:0009061]; formate oxidation [GO:0015944]	periplasmic space [GO:0042597]	formate dehydrogenase complex [GO:0009326]; membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (cytochrome-c-553) activity [GO:0047111]; formate dehydrogenase (NAD+) activity [GO:0008863]; formate dehydrogenase (quinone) activity [GO:0036397]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; selenium binding [GO:0008430]
d1dmra2_d1vlfs2__1			Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	
d1dmta__d1hv5a___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; brush border [GO:0005903]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; cardiolipin binding [GO:1901612]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; oligopeptidase activity [GO:0070012]; peptide binding [GO:0042277]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; aging [GO:0007568]; amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; learning or memory [GO:0007611]; lung development [GO:0030324]; neuropeptide processing [GO:0061837]; neutrophil degranulation [GO:0043312]; peptide metabolic process [GO:0006518]; placenta development [GO:0001890]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neurogenesis [GO:0050769]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; basement membrane organization [GO:0071711]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; negative regulation of fat cell differentiation [GO:0045599]	aging [GO:0007568]; amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; learning or memory [GO:0007611]; lung development [GO:0030324]; neuropeptide processing [GO:0061837]; neutrophil degranulation [GO:0043312]; peptide metabolic process [GO:0006518]; placenta development [GO:0001890]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neurogenesis [GO:0050769]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	basement membrane organization [GO:0071711]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; negative regulation of fat cell differentiation [GO:0045599]	axon [GO:0030424]; brush border [GO:0005903]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	cardiolipin binding [GO:1901612]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; oligopeptidase activity [GO:0070012]; peptide binding [GO:0042277]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]
d1dmxb__d5dspa___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; gluconeogenesis [GO:0006094]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	gluconeogenesis [GO:0006094]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	mitochondrion [GO:0005739]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1dmya__d5tt8c___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; gluconeogenesis [GO:0006094]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	gluconeogenesis [GO:0006094]		mitochondrion [GO:0005739]		carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1dmza__d2lc1a1__1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	cell wall [GO:0005618]; cytosol [GO:0005829]; mRNA binding [GO:0003729]	deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cell wall [GO:0005618]; cytosol [GO:0005829]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]	mRNA binding [GO:0003729]
d1dn0a1_d5iuee2__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1dn0a2_d3et9f2__1	Metazoa		Chordata									
d1dn0c1_d3bh8a1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1dn0d1_d2vxum1__1	Metazoa		Chordata									
d1dn0d1_d5mo9l1__1	Metazoa	Metazoa	Chordata	Chordata		axon [GO:0030424]; axon terminus [GO:0043679]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; brain-derived neurotrophic factor binding [GO:0048403]; brain-derived neurotrophic factor-activated receptor activity [GO:0060175]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of phospholipase C activity [GO:0007202]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cellular response to amino acid stimulus [GO:0071230]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; circadian rhythm [GO:0007623]; feeding behavior [GO:0007631]; glutamate secretion [GO:0014047]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuronal action potential propagation [GO:0019227]; neurotrophin TRK receptor signaling pathway [GO:0048011]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system neuron development [GO:0048935]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; retinal rod cell development [GO:0046548]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trans-synaptic signaling by neuropeptide, modulating synaptic transmission [GO:0099551]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]		activation of phospholipase C activity [GO:0007202]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cellular response to amino acid stimulus [GO:0071230]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; circadian rhythm [GO:0007623]; feeding behavior [GO:0007631]; glutamate secretion [GO:0014047]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neuronal action potential propagation [GO:0019227]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neurotrophin TRK receptor signaling pathway [GO:0048011]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system neuron development [GO:0048935]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; retinal rod cell development [GO:0046548]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trans-synaptic signaling by neuropeptide, modulating synaptic transmission [GO:0099551]; vasculogenesis [GO:0001570]		axon [GO:0030424]; axon terminus [GO:0043679]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]		ATP binding [GO:0005524]; brain-derived neurotrophic factor-activated receptor activity [GO:0060175]; brain-derived neurotrophic factor binding [GO:0048403]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1dn2a1_d1zlwm1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1dn2b1_d4wi8b1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1do3a__d4g51d___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1do5d__d1sxsb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; protein disulfide oxidoreductase activity [GO:0015035]; superoxide dismutase copper chaperone activity [GO:0016532]; cellular response to oxidative stress [GO:0034599]; metal ion transport [GO:0030001]; positive regulation of oxidoreductase activity [GO:0051353]; protein maturation by copper ion transfer [GO:0015680]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	cellular response to oxidative stress [GO:0034599]; metal ion transport [GO:0030001]; positive regulation of oxidoreductase activity [GO:0051353]; protein maturation by copper ion transfer [GO:0015680]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; protein disulfide oxidoreductase activity [GO:0015035]; superoxide dismutase copper chaperone activity [GO:0016532]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1doab__d2jsfa2__1	Metazoa		Chordata		apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	protein dimerization activity [GO:0046983]
d1doba2_d1l9db2__1			Proteobacteria	Firmicutes	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	benzoate catabolic process via hydroxylation [GO:0043640]	tetrahydrofolate metabolic process [GO:0046653]		cytoplasm [GO:0005737]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	sarcosine oxidase activity [GO:0008115]
d1doca2_d1ojba4__1			Proteobacteria		4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]		benzoate catabolic process via hydroxylation [GO:0043640]				4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	
d1doda2_d1ddof2__1		Metazoa	Proteobacteria	Chordata	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	benzoate catabolic process via hydroxylation [GO:0043640]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]		cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d1doga__d2fuza___1	Fungi		Ascomycota	Firmicutes	glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	cytoplasm [GO:0005737]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]		cytoplasm [GO:0005737]	glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]	hydrolase activity, acting on glycosyl bonds [GO:0016798]
d1doga__d3eqaa___1	Fungi	Fungi	Ascomycota	Ascomycota	glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	endoplasmic reticulum [GO:0005783]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]; polysaccharide metabolic process [GO:0005976]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]; polysaccharide metabolic process [GO:0005976]		endoplasmic reticulum [GO:0005783]	glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]	glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]
d1doha__d2iz1c1__1	Fungi		Ascomycota	Firmicutes	tetrahydroxynaphthalene reductase activity [GO:0047039]; melanin biosynthetic process [GO:0042438]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	melanin biosynthetic process [GO:0042438]	D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]			tetrahydroxynaphthalene reductase activity [GO:0047039]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]
d1doha__d3dwfb___1	Fungi	Metazoa	Ascomycota	Chordata	tetrahydroxynaphthalene reductase activity [GO:0047039]; melanin biosynthetic process [GO:0042438]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; lung development [GO:0030324]; steroid metabolic process [GO:0008202]	melanin biosynthetic process [GO:0042438]	lung development [GO:0030324]; steroid metabolic process [GO:0008202]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	tetrahydroxynaphthalene reductase activity [GO:0047039]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]
d1doia__d2b76b2__1			Euryarchaeota	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1doma__d2q8td___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR2 chemokine receptor binding [GO:0031727]; chemokine activity [GO:0008009]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; astrocyte cell migration [GO:0043615]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular homeostasis [GO:0019725]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; helper T cell extravasation [GO:0035684]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of natural killer cell chemotaxis [GO:2000502]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of calcium ion import [GO:0090280]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of T cell activation [GO:0050870]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; viral genome replication [GO:0019079]	cell [GO:0005623]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; astrocyte cell migration [GO:0043615]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular homeostasis [GO:0019725]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; helper T cell extravasation [GO:0035684]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of natural killer cell chemotaxis [GO:2000502]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of calcium ion import [GO:0090280]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of T cell activation [GO:0050870]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; viral genome replication [GO:0019079]	cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell [GO:0005623]; extracellular space [GO:0005615]	CCR2 chemokine receptor binding [GO:0031727]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]	CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]
d1domb__d1tvxd___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR2 chemokine receptor binding [GO:0031727]; chemokine activity [GO:0008009]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; astrocyte cell migration [GO:0043615]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular homeostasis [GO:0019725]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; helper T cell extravasation [GO:0035684]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of natural killer cell chemotaxis [GO:2000502]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of calcium ion import [GO:0090280]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of T cell activation [GO:0050870]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; viral genome replication [GO:0019079]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; tertiary granule lumen [GO:1904724]; chemokine activity [GO:0008009]; glucose transmembrane transporter activity [GO:0005355]; growth factor activity [GO:0008083]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; defense response to bacterium [GO:0042742]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose transmembrane transport [GO:1904659]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of cell division [GO:0051781]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; astrocyte cell migration [GO:0043615]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular homeostasis [GO:0019725]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; helper T cell extravasation [GO:0035684]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of natural killer cell chemotaxis [GO:2000502]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of calcium ion import [GO:0090280]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of T cell activation [GO:0050870]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; viral genome replication [GO:0019079]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; defense response to bacterium [GO:0042742]; glucose transmembrane transport [GO:1904659]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of cell division [GO:0051781]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; tertiary granule lumen [GO:1904724]	CCR2 chemokine receptor binding [GO:0031727]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]	chemokine activity [GO:0008009]; glucose transmembrane transporter activity [GO:0005355]; growth factor activity [GO:0008083]
d1dota2_d1ytvb___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	extracellular space [GO:0005615]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1doxa__d2wp9b1__1			Cyanobacteria	Proteobacteria	cytosol [GO:0005829]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]		aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d1doza__d2qd1b___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	heme biosynthetic process [GO:0006783]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cytoplasm [GO:0005737]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d1dp0a4_d3t09d5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1dp0b2_d2vzua2__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1dp0c5_d3muz13__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1dp0d2_d5a1ac2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1dp0d5_d3bawa2__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	lactose catabolic process [GO:0005990]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	beta-galactosidase complex [GO:0009341]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1dp4a__d3tb6a___1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; guanylate cyclase activity [GO:0004383]; natriuretic peptide receptor activity [GO:0016941]; peptide hormone binding [GO:0017046]; peptide receptor activity [GO:0001653]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; guanylate cyclase activity [GO:0004383]; natriuretic peptide receptor activity [GO:0016941]; peptide hormone binding [GO:0017046]; peptide receptor activity [GO:0001653]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1dp5a__d2qnqb___1	Fungi		Ascomycota		endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]; autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1dp6a__d2i9va___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]		ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d1dp8a__d3ve4a___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]		ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d1dp9a__d3s7qa1__1			Proteobacteria	Deinococcus-Thermus	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]		ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d1dpba__d2ihwa___1		Metazoa	Proteobacteria	Chordata	pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	glycolytic process [GO:0006096]		pyruvate dehydrogenase complex [GO:0045254]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1dpca__d1q9jb2__1			Proteobacteria	Actinobacteria	pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	O-acyltransferase activity [GO:0008374]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; DIM/DIP cell wall layer assembly [GO:0071770]; lipid biosynthetic process [GO:0008610]	glycolytic process [GO:0006096]	DIM/DIP cell wall layer assembly [GO:0071770]; lipid biosynthetic process [GO:0008610]	pyruvate dehydrogenase complex [GO:0045254]		dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]	O-acyltransferase activity [GO:0008374]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1dpda__d2claa___1			Proteobacteria	Proteobacteria	pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	glycolytic process [GO:0006096]	response to antibiotic [GO:0046677]	pyruvate dehydrogenase complex [GO:0045254]		dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d1dpda__d2ii5a___1		Metazoa	Proteobacteria	Chordata	pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	glycolytic process [GO:0006096]		pyruvate dehydrogenase complex [GO:0045254]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1dpfa__d5v6vb___1	Metazoa	Metazoa	Chordata	Chordata	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]; actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]	GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]
d1dpja__d5p6xa___1	Fungi	Fungi	Ascomycota	Ascomycota	endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]; autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	aspartic-type endopeptidase activity [GO:0004190]	autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]		endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]		aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]
d1dppg__d3mzbb___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; dipeptide transmembrane transporter activity [GO:0071916]; heme binding [GO:0020037]; peptide binding [GO:0042277]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; chemotaxis [GO:0006935]; dipeptide transport [GO:0042938]; protein transport [GO:0015031]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	chaperone-mediated protein folding [GO:0061077]; chemotaxis [GO:0006935]; dipeptide transport [GO:0042938]; protein transport [GO:0015031]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	dipeptide transmembrane transporter activity [GO:0071916]; heme binding [GO:0020037]; peptide binding [GO:0042277]; peptide transmembrane transporter activity [GO:1904680]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]
d1dppg__d4yb7a1__1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; dipeptide transmembrane transporter activity [GO:0071916]; heme binding [GO:0020037]; peptide binding [GO:0042277]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; chemotaxis [GO:0006935]; dipeptide transport [GO:0042938]; protein transport [GO:0015031]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	chaperone-mediated protein folding [GO:0061077]; chemotaxis [GO:0006935]; dipeptide transport [GO:0042938]; protein transport [GO:0015031]	histidine biosynthetic process [GO:0000105]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]	dipeptide transmembrane transporter activity [GO:0071916]; heme binding [GO:0020037]; peptide binding [GO:0042277]; peptide transmembrane transporter activity [GO:1904680]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d1dpsa__d1umnf___1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytoplasm [GO:0005737]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d1dpsb__d3ak9c___1			Proteobacteria		cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]		cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]		cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	
d1dpsc__d3uoip___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1dpsf__d3e1qf___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1dpsj__d4d8fb1__1			Proteobacteria	Chlamydiae	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ribonucleoside-diphosphate reductase complex [GO:0005971]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1dpsk__d2x17p___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d1dpxa__d188la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1dpza__d1v5bc___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	leucine biosynthetic process [GO:0009098]	leucine biosynthetic process [GO:0009098]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1dq6a__d2exid1__1	Viridiplantae		Streptophyta	Firmicutes	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1dq6a__d3woga___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; toxin activity [GO:0090729]; defense response [GO:0006952]		defense response [GO:0006952]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; toxin activity [GO:0090729]
d1dqdh1_d1u8ia1__1												
d1dqdl2_d4bsva1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1dqea__d2wcka___1	Metazoa	Metazoa	Arthropoda	Arthropoda	pheromone binding [GO:0005550]; response to pheromone [GO:0019236]	odorant binding [GO:0005549]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	response to pheromone [GO:0019236]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]			pheromone binding [GO:0005550]	odorant binding [GO:0005549]
d1dqid__d2ji3c1__1			Euryarchaeota	Proteobacteria	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]			iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d1dqja1_d4lrnl___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; monomeric IgA immunoglobulin complex [GO:0071748]; pentameric IgM immunoglobulin complex [GO:0071756]; plasma membrane [GO:0005886]; secretory IgA immunoglobulin complex [GO:0071751]; antigen binding [GO:0003823]; antibacterial humoral response [GO:0019731]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antibacterial humoral response [GO:0019731]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; monomeric IgA immunoglobulin complex [GO:0071748]; pentameric IgM immunoglobulin complex [GO:0071756]; plasma membrane [GO:0005886]; secretory IgA immunoglobulin complex [GO:0071751]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]
d1dqjb1_d4enee2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1dqkb__d1vzib1__1			Euryarchaeota	Proteobacteria	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]			iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d1dqmh1_d4w70a___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1dqmh2_d1wc7l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1dqml1_d5vl3d1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; carbohydrate binding [GO:0030246]; CD4 receptor binding [GO:0042609]; IgM binding [GO:0001791]; protein phosphatase binding [GO:0019903]; sialic acid binding [GO:0033691]; signaling receptor binding [GO:0005102]; B cell activation [GO:0042113]; cell adhesion [GO:0007155]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of immunoglobulin secretion [GO:0051025]; regulation of B cell proliferation [GO:0030888]; regulation of endocytosis [GO:0030100]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell activation [GO:0042113]; cell adhesion [GO:0007155]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of immunoglobulin secretion [GO:0051025]; regulation of B cell proliferation [GO:0030888]; regulation of endocytosis [GO:0030100]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	carbohydrate binding [GO:0030246]; CD4 receptor binding [GO:0042609]; IgM binding [GO:0001791]; protein phosphatase binding [GO:0019903]; sialic acid binding [GO:0033691]; signaling receptor binding [GO:0005102]
d1dqml2_d1dbal1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1dqpa__d1eccb1__1				Proteobacteria	transferase activity, transferring glycosyl groups [GO:0016757]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	nucleoside metabolic process [GO:0009116]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	transferase activity, transferring glycosyl groups [GO:0016757]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]
d1dqqa2_d3d5of1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1dqta__d4gw5c1__1	Metazoa		Chordata		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]			
d1dqva1_d2cjtc___1	Metazoa	Metazoa	Chordata	Chordata	exocytic vesicle [GO:0070382]; integral component of synaptic membrane [GO:0099699]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; clathrin binding [GO:0030276]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; positive regulation of vesicle fusion [GO:0031340]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; response to calcium ion [GO:0051592]; synaptic vesicle exocytosis [GO:0016079]; vesicle-mediated transport [GO:0016192]	cell junction [GO:0030054]; excitatory synapse [GO:0060076]; Golgi-associated vesicle [GO:0005798]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; presynaptic active zone cytoplasmic component [GO:0098831]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; synaptic membrane [GO:0097060]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; diacylglycerol binding [GO:0019992]; identical protein binding [GO:0042802]; phospholipid binding [GO:0005543]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; SNARE binding [GO:0000149]; spectrin binding [GO:0030507]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; cell differentiation [GO:0030154]; dense core granule priming [GO:0061789]; intracellular signal transduction [GO:0035556]; long-term synaptic potentiation [GO:0060291]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; presynaptic dense core vesicle exocytosis [GO:0099525]; regulation of synaptic vesicle priming [GO:0010807]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle priming [GO:0016082]	calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; positive regulation of vesicle fusion [GO:0031340]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; response to calcium ion [GO:0051592]; synaptic vesicle exocytosis [GO:0016079]; vesicle-mediated transport [GO:0016192]	cell differentiation [GO:0030154]; dense core granule priming [GO:0061789]; intracellular signal transduction [GO:0035556]; long-term synaptic potentiation [GO:0060291]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; presynaptic dense core vesicle exocytosis [GO:0099525]; regulation of synaptic vesicle priming [GO:0010807]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle priming [GO:0016082]	exocytic vesicle [GO:0070382]; integral component of synaptic membrane [GO:0099699]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658]	cell junction [GO:0030054]; excitatory synapse [GO:0060076]; Golgi-associated vesicle [GO:0005798]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; presynaptic active zone cytoplasmic component [GO:0098831]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; synaptic membrane [GO:0097060]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; clathrin binding [GO:0030276]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]	calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; diacylglycerol binding [GO:0019992]; identical protein binding [GO:0042802]; phospholipid binding [GO:0005543]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; SNARE binding [GO:0000149]; spectrin binding [GO:0030507]; syntaxin-1 binding [GO:0017075]; syntaxin binding [GO:0019905]
d1dqxb__d2zz6a___1	Fungi		Ascomycota	Euryarchaeota	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]		orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1dqya__d3fytf___1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	acetylesterase activity [GO:0008126]	glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; extracellular region [GO:0005576]		diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]	acetylesterase activity [GO:0008126]
d1dqza__d1va5b___1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	cell wall [GO:0005618]; extracellular region [GO:0005576]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	cell wall [GO:0005618]; extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]	diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]
d1dr3a__d1rx9a___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	mitochondrion [GO:0005739]	cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d1dr9a1_d4odxb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; coreceptor activity [GO:0015026]; virus receptor activity [GO:0001618]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0045425]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of signal transduction [GO:0009967]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; monomeric IgA immunoglobulin complex [GO:0071748]; pentameric IgM immunoglobulin complex [GO:0071756]; plasma membrane [GO:0005886]; secretory IgA immunoglobulin complex [GO:0071751]; antigen binding [GO:0003823]; antibacterial humoral response [GO:0019731]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0045425]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of signal transduction [GO:0009967]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	antibacterial humoral response [GO:0019731]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; monomeric IgA immunoglobulin complex [GO:0071748]; pentameric IgM immunoglobulin complex [GO:0071756]; plasma membrane [GO:0005886]; secretory IgA immunoglobulin complex [GO:0071751]	coreceptor activity [GO:0015026]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]
d1drba__d1sejb1__1			Proteobacteria	Apicomplexa	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]
d1drba__d2d5nc1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d1drka__d4rk0c___1			Proteobacteria	Firmicutes	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; monosaccharide binding [GO:0048029]; D-ribose transmembrane transport [GO:0015752]; positive chemotaxis [GO:0050918]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	D-ribose transmembrane transport [GO:0015752]; positive chemotaxis [GO:0050918]	regulation of transcription, DNA-templated [GO:0006355]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]		monosaccharide binding [GO:0048029]	DNA binding [GO:0003677]
d1drma__d3ulfd___1			Proteobacteria		integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]		integral component of plasma membrane [GO:0005887]		ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d1drqa__d2z6db___1		Viridiplantae		Streptophyta		cell [GO:0005623]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plastid [GO:0009536]; ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein serine/threonine kinase activity [GO:0004674]; chloroplast relocation [GO:0009902]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-chromophore linkage [GO:0018298]; response to blue light [GO:0009637]; stomatal movement [GO:0010118]		chloroplast relocation [GO:0009902]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; protein phosphorylation [GO:0006468]; response to blue light [GO:0009637]; stomatal movement [GO:0010118]		cell [GO:0005623]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plastid [GO:0009536]		ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein serine/threonine kinase activity [GO:0004674]
d1ds1a__d5fyhb___1		Metazoa	Actinobacteria	Chordata	clavaminate synthase activity [GO:0033758]; iron ion binding [GO:0005506]; clavulanic acid biosynthetic process [GO:0033050]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	clavulanic acid biosynthetic process [GO:0033050]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]		histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	clavaminate synthase activity [GO:0033758]; iron ion binding [GO:0005506]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1ds8t1_d5nj4h2__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	integral component of membrane [GO:0016021]; plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1dsfl__d4gafb2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]		cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]		interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]
d1dsga__d2ghcx1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	chloroplast [GO:0009507]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1dsoa__d1dnu.1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]; chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1dspa__d4nvmb___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1dsta__d2vwla___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1dsua__d1a1r.1__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]
d1dswa__d1s4ia___1	Metazoa		Chordata	Firmicutes	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; removal of superoxide radicals [GO:0019430]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	removal of superoxide radicals [GO:0019430]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	plasma membrane [GO:0005886]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1dt0b1_d1idsd1__1			Proteobacteria	Actinobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1dt0b2_d2aw9a2__1			Proteobacteria	Deinococcus-Thermus	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1dt0c2_d1gv3a2__1			Proteobacteria	Cyanobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1dt0c2_d3tqja2__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				cytosol [GO:0005829]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1dt2a__d1j16a___1		Metazoa	Firmicutes	Chordata	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]		collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]
d1dt3b__d3fyuf___1	Fungi		Ascomycota	Firmicutes	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	acetylesterase activity [GO:0008126]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	acetylesterase activity [GO:0008126]
d1dt4a__d1zzjb2__1	Metazoa	Metazoa	Chordata	Chordata	intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; synapse [GO:0045202]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; chemical synaptic transmission [GO:0007268]; locomotory behavior [GO:0007626]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of cold-induced thermogenesis [GO:0120163]; regulation of RNA metabolic process [GO:0051252]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]	catalytic step 2 spliceosome [GO:0071013]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; podosome [GO:0002102]; cadherin binding [GO:0045296]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded DNA binding [GO:0003697]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045716]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902165]; regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter [GO:0072369]; regulation of low-density lipoprotein particle clearance [GO:0010988]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; signal transduction [GO:0007165]; viral process [GO:0016032]	chemical synaptic transmission [GO:0007268]; locomotory behavior [GO:0007626]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of cold-induced thermogenesis [GO:0120163]; regulation of RNA metabolic process [GO:0051252]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]	mRNA splicing, via spliceosome [GO:0000398]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045716]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902165]; regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter [GO:0072369]; regulation of low-density lipoprotein particle clearance [GO:0010988]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; signal transduction [GO:0007165]; viral process [GO:0016032]	intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; synapse [GO:0045202]	catalytic step 2 spliceosome [GO:0071013]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; podosome [GO:0002102]	mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]	cadherin binding [GO:0045296]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded DNA binding [GO:0003697]
d1dt5b__d3heab___1	Fungi		Ascomycota	Proteobacteria	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]
d1dt5c__d1tk3b2__1	Fungi	Metazoa	Ascomycota	Chordata	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	triglyceride lipase activity [GO:0004806]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1dt5e__d1qz3a___1	Fungi		Ascomycota	Firmicutes	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	hydrolase activity [GO:0016787]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	hydrolase activity [GO:0016787]
d1dt5e__d5a71a___1	Fungi	Fungi	Ascomycota	Basidiomycota	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]			triglyceride lipase activity [GO:0004806]	triglyceride lipase activity [GO:0004806]
d1dt5h__d5lk6b___1	Fungi		Ascomycota	Crenarchaeota	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	hydrolase activity [GO:0016787]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	hydrolase activity [GO:0016787]
d1dt9a3_d4af1a1__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; translation release factor complex [GO:0018444]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; translation release factor activity [GO:0003747]; translation release factor activity, codon specific [GO:0016149]; translation termination factor activity [GO:0008079]; cytoplasmic translational termination [GO:0002184]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein methylation [GO:0006479]; regulation of translational termination [GO:0006449]	cytoplasm [GO:0005737]; translation release factor activity, codon specific [GO:0016149]	cytoplasmic translational termination [GO:0002184]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein methylation [GO:0006479]; regulation of translational termination [GO:0006449]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; translation release factor complex [GO:0018444]	cytoplasm [GO:0005737]	ribosome binding [GO:0043022]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; translation release factor activity [GO:0003747]; translation release factor activity, codon specific [GO:0016149]; translation termination factor activity [GO:0008079]	translation release factor activity, codon specific [GO:0016149]
d1dtha__d1buda___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; collagen catabolic process [GO:0030574]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; pathogenesis [GO:0009405]	collagen catabolic process [GO:0030574]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1dtia__d5lfgb___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1dtua1_d5ijua___1			Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	
d1dtwb1_d2bp7f1__1	Metazoa		Chordata	Proteobacteria	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]		mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]		3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]
d1dtyb__d1wyvf___1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	biotin biosynthetic process [GO:0009102]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]		adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]
d1dtza1_d2xxxd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; specific granule [GO:0042581]; iron ion binding [GO:0005506]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	extracellular space [GO:0005615]; specific granule [GO:0042581]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	iron ion binding [GO:0005506]; serine-type endopeptidase activity [GO:0004252]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d1du4a__d4b9aa___1	Fungi		Ascomycota	Proteobacteria	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	hydrolase activity [GO:0016787]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	hydrolase activity [GO:0016787]
d1du4c__d1mx9k___1	Fungi	Metazoa	Ascomycota	Chordata	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	lipid catabolic process [GO:0016042]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	triglyceride lipase activity [GO:0004806]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d1du4d__d1lpma___1	Fungi	Fungi	Ascomycota	Ascomycota	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]			triglyceride lipase activity [GO:0004806]	triglyceride lipase activity [GO:0004806]
d1dubb__d1jxza___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	4-chlorobenzoyl-CoA dehalogenase activity [GO:0018787]; coenzyme A metabolic process [GO:0015936]	fatty acid beta-oxidation [GO:0006635]	coenzyme A metabolic process [GO:0015936]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]	4-chlorobenzoyl-CoA dehalogenase activity [GO:0018787]
d1dubc__d1sg4a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	fatty acid beta-oxidation [GO:0006635]	fatty acid beta-oxidation [GO:0006635]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]	dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d1duca__d3hhqo___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; UTP binding [GO:0002134]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; UTP binding [GO:0002134]; zinc ion binding [GO:0008270]	dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1duea__d1sgye___1		Metazoa	Firmicutes	Chordata	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]				extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1duga1_d5ecqf2__1	Metazoa	Viridiplantae	Platyhelminthes	Streptophyta	glutathione transferase activity [GO:0004364]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]		glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]		apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	glutathione transferase activity [GO:0004364]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1duga2_d1ml6a2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]		glutathione metabolic process [GO:0006749]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]	glutathione transferase activity [GO:0004364]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1dugb2_d1ac1b___1	Metazoa		Platyhelminthes	Proteobacteria	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]		cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]		cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	glutathione transferase activity [GO:0004364]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d1duka__d1ngkl___1	Metazoa		Chordata	Actinobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1duna__d4ooqc___1		Viridiplantae		Streptophyta	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; UTP binding [GO:0002134]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	cytosol [GO:0005829]; dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]		cytosol [GO:0005829]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; UTP binding [GO:0002134]; zinc ion binding [GO:0008270]	dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1duoa__d5nb4h___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1dupa1_d3c2ta___1			Proteobacteria		cytosol [GO:0005829]; protein-containing complex [GO:0032991]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1duta__d1q5uy1__1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]		extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d1duvg1_d2i6ua2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1duvg2_d1r0ba1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1duvh1_d1i5oc2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1duvh1_d3r7fb1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1duvh2_d1r0cg2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1duxc__d1ixsb1__1	Metazoa		Chordata	Deinococcus-Thermus	axon terminus [GO:0043679]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to testosterone stimulus [GO:0071394]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to testosterone stimulus [GO:0071394]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	axon terminus [GO:0043679]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]
d1duxc__d3ri4d___1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to testosterone stimulus [GO:0071394]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to testosterone stimulus [GO:0071394]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	axon terminus [GO:0043679]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1duxf__d2nnyb___1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to testosterone stimulus [GO:0071394]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to testosterone stimulus [GO:0071394]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	axon terminus [GO:0043679]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1duxf__d2p7cb1__1	Metazoa		Chordata	Firmicutes	axon terminus [GO:0043679]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to testosterone stimulus [GO:0071394]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to testosterone stimulus [GO:0071394]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	axon terminus [GO:0043679]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]	DNA binding [GO:0003677]
d1duye__d3rvxc1__1	Metazoa	Metazoa	Chordata	Arthropoda	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cysteine-type peptidase activity [GO:0008234]
d1duzd1_d1d5ih1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1duzd2_d2fsec2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1duzd2_d2yeza1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	protein homodimerization activity [GO:0042803]
d1dv1a1_d2c00b3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1dv1a2_d2r7ka1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]
d1dv1b1_d5veva3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d1dv2a2_d1c30g3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1dv2a3_d1t36g5__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1dv2a3_d2nuab2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d1dv2b2_d4zolf1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]; tubulin binding [GO:0015631]; microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	tubulin binding [GO:0015631]
d1dv9a__d4eejb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]		epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1dvai__d2bdij___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1dvba1_d2jd8i___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]	cell [GO:0005623]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d1dvda__d1iv7b___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]		cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]	
d1dvia__d1gjyb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; proteolysis [GO:0006508]	membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]; calcium ion binding [GO:0005509]	proteolysis [GO:0006508]		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]	calcium ion binding [GO:0005509]
d1dvjc1_d3bara2__1			Euryarchaeota	Apicomplexa	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1dvpa1_d4hfga___1	Metazoa	Metazoa	Arthropoda	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; endosome [GO:0005768]; perinuclear region of cytoplasm [GO:0048471]; metal ion binding [GO:0046872]; ubiquitin binding [GO:0043130]; early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosome transport via multivesicular body sorting pathway [GO:0032509]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of torso signaling pathway [GO:0120177]; neuron remodeling [GO:0016322]; positive regulation of border follicle cell migration [GO:1903688]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of Toll signaling pathway [GO:0045752]; positive regulation of Wnt protein secretion [GO:0061357]; receptor internalization [GO:0031623]; regulation of cell cycle [GO:0051726]; regulation of epithelial cell migration, open tracheal system [GO:2000274]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II, holoenzyme [GO:0016591]; identical protein binding [GO:0042802]; RNA polymerase II complex binding [GO:0000993]; dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; mRNA 3'-end processing [GO:0031124]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle process [GO:0010564]; snRNA transcription by RNA polymerase II [GO:0042795]	early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosome transport via multivesicular body sorting pathway [GO:0032509]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of torso signaling pathway [GO:0120177]; neuron remodeling [GO:0016322]; positive regulation of border follicle cell migration [GO:1903688]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of Toll signaling pathway [GO:0045752]; positive regulation of Wnt protein secretion [GO:0061357]; receptor internalization [GO:0031623]; regulation of cell cycle [GO:0051726]; regulation of epithelial cell migration, open tracheal system [GO:2000274]	dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; mRNA 3'-end processing [GO:0031124]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle process [GO:0010564]; snRNA transcription by RNA polymerase II [GO:0042795]	cell cortex [GO:0005938]; cytosol [GO:0005829]; endosome [GO:0005768]; perinuclear region of cytoplasm [GO:0048471]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II, holoenzyme [GO:0016591]	metal ion binding [GO:0046872]; ubiquitin binding [GO:0043130]	identical protein binding [GO:0042802]; RNA polymerase II complex binding [GO:0000993]
d1dvsb__d2h6ug___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1dvua__d3imva___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1dvva__d3zoyd___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1dvyb__d4q14a___1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]		hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydroxyisourate hydrolase activity [GO:0033971]
d1dw0a__d2zong___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]			electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1dw0b__d2c1vb2__1			Proteobacteria		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]						electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d1dw1a__d1kibd___1			Proteobacteria	Cyanobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	thylakoid lumen [GO:0031977]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]		thylakoid lumen [GO:0031977]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1dw2c__d2c1dc1__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1dw3a__d1m6za1__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1dw3a__d3zowg___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1dwfm__d3baia2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	vacuole [GO:0005773]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1dwhm__d1l0pa2__1	Viridiplantae		Streptophyta	Proteobacteria	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	vacuole [GO:0005773]	extracellular region [GO:0005576]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d1dwim__d1oifa___1	Viridiplantae		Streptophyta	Thermotogae	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	vacuole [GO:0005773]		glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1dwjm__d2zx7b1__1	Viridiplantae		Streptophyta	Thermotogae	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	vacuole [GO:0005773]	lysosome [GO:0005764]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]	alpha-L-fucosidase activity [GO:0004560]
d1dwnc__d2c51c___1					viral capsid [GO:0019028]	T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]		regulation of translation [GO:0006417]	viral capsid [GO:0019028]	T=3 icosahedral viral capsid [GO:0039617]		identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1dwoa1_d1broa___1	Viridiplantae		Streptophyta	Actinobacteria	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	peroxidase activity [GO:0004601]; antibiotic biosynthetic process [GO:0017000]		antibiotic biosynthetic process [GO:0017000]			aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	peroxidase activity [GO:0004601]
d1dwpa1_d2wfmc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	polyneuridine-aldehyde esterase activity [GO:0050529]; alkaloid metabolic process [GO:0009820]		alkaloid metabolic process [GO:0009820]			aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	polyneuridine-aldehyde esterase activity [GO:0050529]
d1dwpa1_d4bc1a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]; acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]		acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]		anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]
d1dwwa__d3e7gb___1	Metazoa	Metazoa	Chordata	Chordata	cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; actin binding [GO:0003779]; arginine binding [GO:0034618]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; cAMP-dependent protein kinase regulator activity [GO:0008603]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; nitric-oxide synthase binding [GO:0050998]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tetrahydrobiopterin binding [GO:0034617]; arginine catabolic process [GO:0006527]; cellular response to cytokine stimulus [GO:0071345]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; circadian rhythm [GO:0007623]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; prostaglandin secretion [GO:0032310]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; arginine binding [GO:0034618]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin binding [GO:0034617]; arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; circadian rhythm [GO:0007623]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of leukocyte mediated cytotoxicity [GO:0001912]; prostaglandin secretion [GO:0032310]; protein targeting to peroxisome [GO:0006625]; regulation of cell population proliferation [GO:0042127]; regulation of cellular respiration [GO:0043457]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	arginine catabolic process [GO:0006527]; cellular response to cytokine stimulus [GO:0071345]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; circadian rhythm [GO:0007623]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; prostaglandin secretion [GO:0032310]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; circadian rhythm [GO:0007623]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of leukocyte mediated cytotoxicity [GO:0001912]; prostaglandin secretion [GO:0032310]; protein targeting to peroxisome [GO:0006625]; regulation of cell population proliferation [GO:0042127]; regulation of cellular respiration [GO:0043457]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	actin binding [GO:0003779]; arginine binding [GO:0034618]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; cAMP-dependent protein kinase regulator activity [GO:0008603]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; nitric-oxide synthase binding [GO:0050998]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tetrahydrobiopterin binding [GO:0034617]	arginine binding [GO:0034618]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin binding [GO:0034617]
d1dx5.3_d2fx6a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1dx5.4_d1tnha___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1dx9a__d2m6ra___1			Cyanobacteria	Proteobacteria	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	FMN binding [GO:0010181]; oxidation-reduction process [GO:0055114]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	cell [GO:0005623]		electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	FMN binding [GO:0010181]
d1dx9a__d5nula___1			Cyanobacteria	Firmicutes	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]		cell [GO:0005623]		electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1dx9c__d3nhpa___1		Metazoa	Cyanobacteria	Chordata	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1dx9d__d1czoa___1			Cyanobacteria	Cyanobacteria	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]		cell [GO:0005623]		electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1dxca__d3wcvd___1	Metazoa	Metazoa	Chordata	Annelida	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1dxha1_d2i6ub2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1dxia__d1xlla___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1dxja__d2z37c___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]			chitinase activity [GO:0004568]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d1dxma__d1gjxa___1	Viridiplantae		Streptophyta	Proteobacteria	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]; glycine decarboxylation via glycine cleavage system [GO:0019464]	cell [GO:0005623]; dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]	glycine decarboxylation via glycine cleavage system [GO:0019464]	cell redox homeostasis [GO:0045454]	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]	cell [GO:0005623]		dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]
d1dxma__d3hgba1__1	Viridiplantae		Streptophyta	Actinobacteria	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]; glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine cleavage complex [GO:0005960]; glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]	glycine cleavage complex [GO:0005960]		
d1dxob__d4u7fb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1dxod__d3ojwa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1dxp.1_d4nwka___1					extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1dxp.1_d4wmfb___1					extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]
d1dxp.2_d5gj4f___1					extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1dxqa__d1dx9d___1	Metazoa		Chordata	Cyanobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]	cell [GO:0005623]	electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1dxqb__d5ljla1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]		electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1dxqd__d2f1ob___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d1dxtb__d1cpca___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1dxtb__d1it2b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1dxtd__d3wcve___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1dxub__d1a01b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1dxva__d2uums___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1dxvd__d2ig3a___1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d1dxvd__d5ksic___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1dxwa1_d3t26a___1		Metazoa		Chordata	serine-type peptidase activity [GO:0008236]; transformation of host cell by virus [GO:0019087]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	transformation of host cell by virus [GO:0019087]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1dxxa1_d1wypa1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]; actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein localization [GO:0034613]; cellular protein-containing complex assembly [GO:0034622]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; actomyosin structure organization [GO:0031032]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; regulation of smooth muscle contraction [GO:0006940]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein-containing complex assembly [GO:0034622]; cellular protein localization [GO:0034613]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	actomyosin structure organization [GO:0031032]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; regulation of smooth muscle contraction [GO:0006940]	cell [GO:0005623]; cell-substrate junction [GO:0030055]; cell surface [GO:0009986]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]	cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]	actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; calmodulin binding [GO:0005516]
d1dxxb1_d2wa6a2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]; actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein localization [GO:0034613]; cellular protein-containing complex assembly [GO:0034622]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein-containing complex assembly [GO:0034622]; cellular protein localization [GO:0034613]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	cell [GO:0005623]; cell-substrate junction [GO:0030055]; cell surface [GO:0009986]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d1dxxb2_d1v5ka1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]; actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein localization [GO:0034613]; cellular protein-containing complex assembly [GO:0034622]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	cell projection [GO:0042995]; cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein kinase binding [GO:0019901]; cell division [GO:0051301]; cell migration [GO:0016477]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein-containing complex assembly [GO:0034622]; cellular protein localization [GO:0034613]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	cell division [GO:0051301]; cell migration [GO:0016477]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	cell [GO:0005623]; cell-substrate junction [GO:0030055]; cell surface [GO:0009986]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]	cell projection [GO:0042995]; cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]	actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein kinase binding [GO:0019901]
d1dxxd1_d2r8ua___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]; actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein localization [GO:0034613]; cellular protein-containing complex assembly [GO:0034622]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; cell division [GO:0051301]; cell migration [GO:0016477]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of cell migration [GO:0030335]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein-containing complex assembly [GO:0034622]; cellular protein localization [GO:0034613]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	cell division [GO:0051301]; cell migration [GO:0016477]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of cell migration [GO:0030335]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	cell [GO:0005623]; cell-substrate junction [GO:0030055]; cell surface [GO:0009986]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]	cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]	actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d1dxxd1_d5a36a2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]; actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein localization [GO:0034613]; cellular protein-containing complex assembly [GO:0034622]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; pseudopodium [GO:0031143]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]; actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein-containing complex assembly [GO:0034622]; cellular protein localization [GO:0034613]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	cell [GO:0005623]; cell-substrate junction [GO:0030055]; cell surface [GO:0009986]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; pseudopodium [GO:0031143]; Z disc [GO:0030018]	actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]
d1dy2a__d1bnlc___1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; extracellular matrix structural constituent [GO:0005201]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; response to drug [GO:0042493]; response to hydrostatic pressure [GO:0051599]; visual perception [GO:0007601]	cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; response to drug [GO:0042493]; response to hydrostatic pressure [GO:0051599]; visual perception [GO:0007601]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1dy7b1_d1n90a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1dy8.2_d1mbmb___1					extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell membrane [GO:0033644]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1dy8.2_d4i8ha___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1dy9.1_d3osya1__1					extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cysteine-type endopeptidase activity [GO:0004197]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	cysteine-type endopeptidase activity [GO:0004197]
d1dy9.2_d1z6jh___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d1dyda__d5j7ca___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1dyfa__d188la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1dyha__d2c2sa___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1dyia__d3fl8c1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1dyib__d3dl5a1__1			Proteobacteria		cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	
d1dyjb__d4elfc1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1dyma__d2e7qa___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		cellulase activity [GO:0008810]	carbohydrate binding [GO:0030246]
d1dyna__d2coca1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendritic spine [GO:0043197]; dendritic spine head [GO:0044327]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane coat [GO:0030117]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic endocytic zone membrane [GO:0098844]; postsynaptic membrane [GO:0045211]; presynaptic endocytic zone membrane [GO:0098835]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; varicosity [GO:0043196]; D2 dopamine receptor binding [GO:0031749]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; endocytosis [GO:0006897]; endosome organization [GO:0007032]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled receptor internalization [GO:0002031]; mitochondrial fission [GO:0000266]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synapse structure or activity [GO:0050803]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; toxin transport [GO:1901998]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; ruffle [GO:0001726]; guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; small GTPase binding [GO:0031267]; actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	endocytosis [GO:0006897]; endosome organization [GO:0007032]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled receptor internalization [GO:0002031]; mitochondrial fission [GO:0000266]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synapse structure or activity [GO:0050803]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; toxin transport [GO:1901998]	actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendritic spine [GO:0043197]; dendritic spine head [GO:0044327]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane coat [GO:0030117]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic endocytic zone membrane [GO:0098844]; postsynaptic membrane [GO:0045211]; presynaptic endocytic zone membrane [GO:0098835]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; varicosity [GO:0043196]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; ruffle [GO:0001726]	D2 dopamine receptor binding [GO:0031749]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]	guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; small GTPase binding [GO:0031267]
d1dyna__d2mdxa1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendritic spine [GO:0043197]; dendritic spine head [GO:0044327]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane coat [GO:0030117]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic endocytic zone membrane [GO:0098844]; postsynaptic membrane [GO:0045211]; presynaptic endocytic zone membrane [GO:0098835]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; varicosity [GO:0043196]; D2 dopamine receptor binding [GO:0031749]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; endocytosis [GO:0006897]; endosome organization [GO:0007032]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled receptor internalization [GO:0002031]; mitochondrial fission [GO:0000266]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synapse structure or activity [GO:0050803]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; toxin transport [GO:1901998]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; ceramide 1-phosphate binding [GO:1902387]; ceramide 1-phosphate transfer activity [GO:1902388]; lipid binding [GO:0008289]; phosphatidylinositol-4-phosphate binding [GO:0070273]; ceramide transport [GO:0035627]; ER to Golgi ceramide transport [GO:0035621]; intermembrane lipid transfer [GO:0120009]; phosphatidylinositol biosynthetic process [GO:0006661]	endocytosis [GO:0006897]; endosome organization [GO:0007032]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled receptor internalization [GO:0002031]; mitochondrial fission [GO:0000266]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synapse structure or activity [GO:0050803]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; toxin transport [GO:1901998]	ceramide transport [GO:0035627]; ER to Golgi ceramide transport [GO:0035621]; intermembrane lipid transfer [GO:0120009]; phosphatidylinositol biosynthetic process [GO:0006661]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendritic spine [GO:0043197]; dendritic spine head [GO:0044327]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane coat [GO:0030117]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic endocytic zone membrane [GO:0098844]; postsynaptic membrane [GO:0045211]; presynaptic endocytic zone membrane [GO:0098835]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; varicosity [GO:0043196]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]	D2 dopamine receptor binding [GO:0031749]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]	ceramide 1-phosphate binding [GO:1902387]; ceramide 1-phosphate transfer activity [GO:1902388]; lipid binding [GO:0008289]; phosphatidylinositol-4-phosphate binding [GO:0070273]
d1dynb__d2m38a___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendritic spine [GO:0043197]; dendritic spine head [GO:0044327]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane coat [GO:0030117]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic endocytic zone membrane [GO:0098844]; postsynaptic membrane [GO:0045211]; presynaptic endocytic zone membrane [GO:0098835]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; varicosity [GO:0043196]; D2 dopamine receptor binding [GO:0031749]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; endocytosis [GO:0006897]; endosome organization [GO:0007032]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled receptor internalization [GO:0002031]; mitochondrial fission [GO:0000266]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synapse structure or activity [GO:0050803]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; toxin transport [GO:1901998]	Cajal body [GO:0015030]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; ephrin receptor binding [GO:0046875]; regulation of synaptic plasticity by receptor localization to synapse [GO:1900383]	endocytosis [GO:0006897]; endosome organization [GO:0007032]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled receptor internalization [GO:0002031]; mitochondrial fission [GO:0000266]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synapse structure or activity [GO:0050803]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; toxin transport [GO:1901998]	regulation of synaptic plasticity by receptor localization to synapse [GO:1900383]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendritic spine [GO:0043197]; dendritic spine head [GO:0044327]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane coat [GO:0030117]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic endocytic zone membrane [GO:0098844]; postsynaptic membrane [GO:0045211]; presynaptic endocytic zone membrane [GO:0098835]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; varicosity [GO:0043196]	Cajal body [GO:0015030]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]	D2 dopamine receptor binding [GO:0031749]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]	ephrin receptor binding [GO:0046875]
d1dysb__d1hgwa___1	Fungi	Fungi	Ascomycota	Ascomycota	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	cellulase activity [GO:0008810]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]
d1dysb__d3abxa___1	Fungi	Fungi	Ascomycota	Basidiomycota	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			cellulase activity [GO:0008810]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1dyza__d2n0ma1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1dz6b__d4l40a___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1dz9b__d2h7ra___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	(+)-camphor catabolic process [GO:0019383]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1dz9b__d3jusb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]; cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	(+)-camphor catabolic process [GO:0019383]	cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]
d1dzbb1_d5m2ih___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d1dzbx__d3dn3a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1dzby__d1t3pa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1dzca__d3ud9a___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1dzjb__d4i3dd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytoplasm [GO:0005737]; lipid binding [GO:0008289]; bioluminescence [GO:0008218]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	bioluminescence [GO:0008218]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	small molecule binding [GO:0036094]	lipid binding [GO:0008289]
d1dzna1_d1wvfa1__1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]		FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]
d1dzoa1_d3cfij___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]; cell adhesion [GO:0007155]	integral component of membrane [GO:0016021]; type II protein secretion system complex [GO:0015627]; protein secretion by the type II secretion system [GO:0015628]	cell adhesion [GO:0007155]	protein secretion by the type II secretion system [GO:0015628]	pilus [GO:0009289]	integral component of membrane [GO:0016021]; type II protein secretion system complex [GO:0015627]		
d1dzpa__d4zgua___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]	small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1dzpb__d4ruub___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]	small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1dzqd__d1f9ka___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1dzqd__d3kqrb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1dzta__d2paea1__1			Proteobacteria	Firmicutes	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	isomerase activity [GO:0016853]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]				dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	isomerase activity [GO:0016853]
d1dztb__d1zz8a2__1			Proteobacteria	Actinobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]			dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d1dzvp__d1e47p___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]	aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]
d1dzzp__d3fuaa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]	aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]
d1e00b__d4i3cb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytoplasm [GO:0005737]; lipid binding [GO:0008289]; bioluminescence [GO:0008218]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	bioluminescence [GO:0008218]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	small molecule binding [GO:0036094]	lipid binding [GO:0008289]
d1e02a__d4getd___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	histamine binding [GO:0051381]; nitric oxide binding [GO:0070026]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]		small molecule binding [GO:0036094]	histamine binding [GO:0051381]; nitric oxide binding [GO:0070026]
d1e02b__d1gt5a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	small molecule binding [GO:0036094]	small molecule binding [GO:0036094]
d1e06a__d5ur9f1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]; epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]	small molecule binding [GO:0036094]	fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]
d1e06b__d1epbb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]; small molecule binding [GO:0036094]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	small molecule binding [GO:0036094]	small molecule binding [GO:0036094]
d1e0da1_d5vvwh1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]	ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]
d1e0f.2_d3e91a___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1e0ia__d3wv6b1__1		Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]
d1e0jc__d4bfva___1				Actinobacteria	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]		coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d1e0kc__d1bmfb3__1		Metazoa		Chordata	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]		ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e0ke__d2hv8c___1		Metazoa		Chordata	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	axon [GO:0030424]; cell [GO:0005623]; centriolar satellite [GO:0034451]; cleavage furrow [GO:0032154]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; multivesicular body [GO:0005771]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; postsynaptic recycling endosome [GO:0098837]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; Schaffer collateral - CA1 synapse [GO:0098685]; spindle pole [GO:0000922]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133]; vesicle [GO:0031982]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; microtubule binding [GO:0008017]; myosin V binding [GO:0031489]; syntaxin binding [GO:0019905]; amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; plasma membrane to endosome transport [GO:0048227]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-translational protein modification [GO:0043687]; protein localization to plasma membrane [GO:0072659]; Rab protein signal transduction [GO:0032482]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; renal water homeostasis [GO:0003091]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003]		amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; plasma membrane to endosome transport [GO:0048227]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-translational protein modification [GO:0043687]; protein localization to plasma membrane [GO:0072659]; Rab protein signal transduction [GO:0032482]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; renal water homeostasis [GO:0003091]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003]		axon [GO:0030424]; cell [GO:0005623]; centriolar satellite [GO:0034451]; cleavage furrow [GO:0032154]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; multivesicular body [GO:0005771]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; postsynaptic recycling endosome [GO:0098837]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; Schaffer collateral - CA1 synapse [GO:0098685]; spindle pole [GO:0000922]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133]; vesicle [GO:0031982]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; microtubule binding [GO:0008017]; myosin V binding [GO:0031489]; syntaxin binding [GO:0019905]
d1e0ke__d2xokd2__1		Fungi		Ascomycota	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]		ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e0sa__d4i1vb1__1	Metazoa		Chordata	Proteobacteria	cell cortex [GO:0005938]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; recycling endosome membrane [GO:0055038]; ruffle [GO:0001726]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein N-terminus binding [GO:0047485]; thioesterase binding [GO:0031996]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to nerve growth factor stimulus [GO:1990090]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; intracellular protein transport [GO:0006886]; liver development [GO:0001889]; maintenance of postsynaptic density structure [GO:0099562]; myeloid cell apoptotic process [GO:0033028]; negative regulation of dendrite development [GO:2000171]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of receptor-mediated endocytosis [GO:0048261]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of presynapse assembly [GO:1905606]; regulation of Rac protein signal transduction [GO:0035020]; ruffle assembly [GO:0097178]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; dephospho-CoA kinase activity [GO:0004140]; coenzyme A biosynthetic process [GO:0015937]	cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to nerve growth factor stimulus [GO:1990090]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; intracellular protein transport [GO:0006886]; liver development [GO:0001889]; maintenance of postsynaptic density structure [GO:0099562]; myeloid cell apoptotic process [GO:0033028]; negative regulation of dendrite development [GO:2000171]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of receptor-mediated endocytosis [GO:0048261]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of presynapse assembly [GO:1905606]; regulation of Rac protein signal transduction [GO:0035020]; ruffle assembly [GO:0097178]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192]	coenzyme A biosynthetic process [GO:0015937]	cell cortex [GO:0005938]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; recycling endosome membrane [GO:0055038]; ruffle [GO:0001726]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein N-terminus binding [GO:0047485]; thioesterase binding [GO:0031996]	ATP binding [GO:0005524]; dephospho-CoA kinase activity [GO:0004140]
d1e0ta3_d2vgid3__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]; response to heat [GO:0009408]	ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1e0tc3_d1aqff3__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]; response to heat [GO:0009408]	positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1e0td3_d1lixa6__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]; response to heat [GO:0009408]		glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]; response to heat [GO:0009408]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	
d1e0ua1_d3ktxb2__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]; response to heat [GO:0009408]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]; response to heat [GO:0009408]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1e0va__d1e4lb___1		Viridiplantae	Actinobacteria	Streptophyta	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	extracellular region [GO:0005576]	chloroplast [GO:0009507]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]
d1e0wa__d5gqda1__1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d1e0xa__d5idib___1			Actinobacteria	Thermotogae	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	glucan 1,4-beta-glucosidase activity [GO:0031217]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	glucan 1,4-beta-glucosidase activity [GO:0031217]; scopolin beta-glucosidase activity [GO:0102483]
d1e0xb__d3f5kb___1		Viridiplantae	Actinobacteria	Streptophyta	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d1e0yb1_d2bvhd1__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]		FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]
d1e18a1_d3hu1c1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	periplasmic space [GO:0042597]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1e19b__d1b7ba___1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]; arginine metabolic process [GO:0006525]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]; arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	arginine metabolic process [GO:0006525]	arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]	ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]
d1e1ba1_d2zwkc1__1				Proteobacteria		cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]		
d1e1cc2_d7reqd2__1			Actinobacteria	Actinobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]					cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d1e1cd1_d1ccwb___1			Actinobacteria	Firmicutes	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]; anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]		anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]			cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]
d1e1eb__d1j10b2__1	Viridiplantae		Streptophyta	Firmicutes	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	polysaccharide catabolic process [GO:0000272]	chloroplast [GO:0009507]		beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1e1fb__d1px3a5__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	lactose catabolic process [GO:0005990]	chloroplast [GO:0009507]	beta-galactosidase complex [GO:0009341]	beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1e1ka1_d1h7xd3__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; NADPH-adrenodoxin reductase activity [GO:0015039]; cholesterol metabolic process [GO:0008203]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; ubiquinone biosynthetic process [GO:0006744]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cholesterol metabolic process [GO:0008203]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; ubiquinone biosynthetic process [GO:0006744]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; NADPH-adrenodoxin reductase activity [GO:0015039]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d1e1la1_d1o95a2__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; NADPH-adrenodoxin reductase activity [GO:0015039]; cholesterol metabolic process [GO:0008203]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; ubiquinone biosynthetic process [GO:0006744]	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	cholesterol metabolic process [GO:0008203]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; ubiquinone biosynthetic process [GO:0006744]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; NADPH-adrenodoxin reductase activity [GO:0015039]	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]
d1e1pa__d1xywa___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	anchored component of membrane [GO:0031225]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; protein homooligomerization [GO:0051260]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	protein homooligomerization [GO:0051260]	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]	anchored component of membrane [GO:0031225]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	copper ion binding [GO:0005507]
d1e1qa1_d2hldm3__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e1qa2_d1efrf2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e1qb3_d3oeed2__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e1qc1_d5ik2f3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e1qc2_d3oe7v1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e1qc3_d1vhtb1__1	Metazoa		Chordata	Proteobacteria	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; dephospho-CoA kinase activity [GO:0004140]; coenzyme A biosynthetic process [GO:0015937]	ATP synthesis coupled proton transport [GO:0015986]	coenzyme A biosynthetic process [GO:0015937]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; dephospho-CoA kinase activity [GO:0004140]
d1e1qe1_d5cdfa3__1	Metazoa		Chordata	Proteobacteria	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e1qe2_d2hldd1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e1qe2_d3gqbd1__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e1rb2_d3vr6d1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e1rd1_d3a5ci4__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e1rd2_d3ziam1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e1rd2_d5hkkj1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e1re1_d5knce3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e1ta1_d1b8aa1__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]; membrane [GO:0016020]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d1e22a1_d3pf5b___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]		cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; nucleoid [GO:0009295]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]	DNA binding [GO:0003677]
d1e22a2_d1nj8a3__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	prolyl-tRNA aminoacylation [GO:0006433]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; proline-tRNA ligase activity [GO:0004827]
d1e24a1_d1ph9a2__1			Proteobacteria	Ciliophora	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	telomere capping [GO:0016233]	cytosol [GO:0005829]; membrane [GO:0016020]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1e27a1_d5ukql2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1e28a1_d5w6gl1__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]
d1e28b__d4wwka2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1e2aa__d3l8rg___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	metal ion binding [GO:0046872]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; transferase activity [GO:0016740]	metal ion binding [GO:0046872]
d1e2ba__d2m1za___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity [GO:0090566]; N,N'-diacetylchitobiose import [GO:1902815]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	plasma membrane [GO:0005886]; protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity [GO:0022877]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	N,N'-diacetylchitobiose import [GO:1902815]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytosol [GO:0005829]	plasma membrane [GO:0005886]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity [GO:0090566]	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity [GO:0022877]
d1e2cb__d4nr3a___1		Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]		DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]		ubiquitin conjugating enzyme activity [GO:0061631]
d1e2cb__d5vkga___1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]; autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]		autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]		calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]
d1e2da__d1guaa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627]; thymidine biosynthetic process [GO:0046105]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; mitogen-activated protein kinase kinase binding [GO:0031434]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; activation of adenylate cyclase activity [GO:0007190]; activation of MAPKK activity [GO:0000186]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; death-inducing signaling complex assembly [GO:0071550]; face development [GO:0060324]; heart development [GO:0007507]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; intermediate filament cytoskeleton organization [GO:0045104]; ion transmembrane transport [GO:0034220]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of protein complex assembly [GO:0031333]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet activation [GO:0030168]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell differentiation [GO:0045595]; regulation of cell motility [GO:2000145]; regulation of Rho protein signal transduction [GO:0035023]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; wound healing [GO:0042060]	cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627]; thymidine biosynthetic process [GO:0046105]	activation of adenylate cyclase activity [GO:0007190]; activation of MAPKK activity [GO:0000186]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; death-inducing signaling complex assembly [GO:0071550]; face development [GO:0060324]; heart development [GO:0007507]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; intermediate filament cytoskeleton organization [GO:0045104]; ion transmembrane transport [GO:0034220]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of protein complex assembly [GO:0031333]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet activation [GO:0030168]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell differentiation [GO:0045595]; regulation of cell motility [GO:2000145]; regulation of Rho protein signal transduction [GO:0035023]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; mitogen-activated protein kinase kinase binding [GO:0031434]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d1e2rb1_d5c9ma___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; glial cell apoptotic process [GO:0034349]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; negative regulation of hydrogen peroxide biosynthetic process [GO:0010730]; positive regulation of cellular respiration [GO:1901857]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to gravity [GO:0009629]; response to ischemia [GO:0002931]; response to oxidative stress [GO:0006979]		apoptotic process [GO:0006915]; glial cell apoptotic process [GO:0034349]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; negative regulation of hydrogen peroxide biosynthetic process [GO:0010730]; positive regulation of cellular respiration [GO:1901857]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to gravity [GO:0009629]; response to ischemia [GO:0002931]; response to oxidative stress [GO:0006979]	periplasmic space [GO:0042597]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1e2ta__d4bgfb___1			Proteobacteria		cytoplasm [GO:0005737]; arylamine N-acetyltransferase activity [GO:0004060]; N-hydroxyarylamine O-acetyltransferase activity [GO:0046990]				cytoplasm [GO:0005737]		arylamine N-acetyltransferase activity [GO:0004060]; N-hydroxyarylamine O-acetyltransferase activity [GO:0046990]	
d1e2td__d4b55a___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; arylamine N-acetyltransferase activity [GO:0004060]; N-hydroxyarylamine O-acetyltransferase activity [GO:0046990]	acetyltransferase activity [GO:0016407]			cytoplasm [GO:0005737]		arylamine N-acetyltransferase activity [GO:0004060]; N-hydroxyarylamine O-acetyltransferase activity [GO:0046990]	acetyltransferase activity [GO:0016407]
d1e32a2_d4kodi3__1	Metazoa	Metazoa	Chordata	Chordata	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1e32a3_d3hu2d2__1	Metazoa	Metazoa	Chordata	Chordata	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1e34b__d1fujd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; enzyme binding [GO:0019899]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; antimicrobial humoral response [GO:0019730]; blood coagulation [GO:0007596]; cell-cell junction maintenance [GO:0045217]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; mature conventional dendritic cell differentiation [GO:0097029]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of phagocytosis [GO:0050765]; neutrophil degranulation [GO:0043312]; neutrophil extravasation [GO:0072672]; phagocytosis [GO:0006909]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of GTPase activity [GO:0043547]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	antimicrobial humoral response [GO:0019730]; blood coagulation [GO:0007596]; cell-cell junction maintenance [GO:0045217]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; mature conventional dendritic cell differentiation [GO:0097029]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of phagocytosis [GO:0050765]; neutrophil degranulation [GO:0043312]; neutrophil extravasation [GO:0072672]; phagocytosis [GO:0006909]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of GTPase activity [GO:0043547]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	enzyme binding [GO:0019899]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d1e35b__d2fs8d___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1e36b__d3osyd1__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	cysteine-type endopeptidase activity [GO:0004197]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]
d1e38b__d4x2va___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]
d1e39a3_d1qlad5__1			Proteobacteria		outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]		anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]		outer membrane-bounded periplasmic space [GO:0030288]		electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]	
d1e3ea2_d1ykfa2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; all-trans retinal binding [GO:0005503]; benzaldehyde dehydrogenase [NAD(P)+] activity [GO:0019115]; ethanol binding [GO:0035276]; NAD binding [GO:0051287]; NADPH:quinone reductase activity [GO:0003960]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; quinone metabolic process [GO:1901661]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; quinone metabolic process [GO:1901661]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]		alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; all-trans retinal binding [GO:0005503]; benzaldehyde dehydrogenase [NAD(P)+] activity [GO:0019115]; ethanol binding [GO:0035276]; NAD binding [GO:0051287]; NADPH:quinone reductase activity [GO:0003960]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]
d1e3ia2_d3d0oa1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; all-trans retinal binding [GO:0005503]; benzaldehyde dehydrogenase [NAD(P)+] activity [GO:0019115]; ethanol binding [GO:0035276]; NAD binding [GO:0051287]; NADPH:quinone reductase activity [GO:0003960]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; quinone metabolic process [GO:1901661]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; quinone metabolic process [GO:1901661]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	glycolytic process [GO:0006096]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; all-trans retinal binding [GO:0005503]; benzaldehyde dehydrogenase [NAD(P)+] activity [GO:0019115]; ethanol binding [GO:0035276]; NAD binding [GO:0051287]; NADPH:quinone reductase activity [GO:0003960]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]	L-lactate dehydrogenase activity [GO:0004459]
d1e3lb2_d1yb5a2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; all-trans retinal binding [GO:0005503]; benzaldehyde dehydrogenase [NAD(P)+] activity [GO:0019115]; ethanol binding [GO:0035276]; NAD binding [GO:0051287]; NADPH:quinone reductase activity [GO:0003960]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; quinone metabolic process [GO:1901661]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mRNA 3'-UTR binding [GO:0003730]; NADPH binding [GO:0070402]; NADPH:quinone reductase activity [GO:0003960]; zinc ion binding [GO:0008270]; protein homotetramerization [GO:0051289]; visual perception [GO:0007601]; xenobiotic catabolic process [GO:0042178]	alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; quinone metabolic process [GO:1901661]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	protein homotetramerization [GO:0051289]; visual perception [GO:0007601]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; all-trans retinal binding [GO:0005503]; benzaldehyde dehydrogenase [NAD(P)+] activity [GO:0019115]; ethanol binding [GO:0035276]; NAD binding [GO:0051287]; NADPH:quinone reductase activity [GO:0003960]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]	mRNA 3'-UTR binding [GO:0003730]; NADPH:quinone reductase activity [GO:0003960]; NADPH binding [GO:0070402]; zinc ion binding [GO:0008270]
d1e3qa__d1odsc___1	Metazoa		Chordata	Firmicutes	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	cytoplasm [GO:0005737]	acetylcholinesterase activity [GO:0003990]	acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]
d1e3ra__d5tuwc2__1			Proteobacteria	Cyanobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	phycobilisome [GO:0030089]; chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]; light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	steroid metabolic process [GO:0008202]	light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	steroid delta-isomerase activity [GO:0004769]	chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]
d1e3wd__d1b8ua1__1	Metazoa		Chordata	Proteobacteria	mitochondrial ribonuclease P complex [GO:0030678]; mitochondrion [GO:0005739]; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity [GO:0047015]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; acetoacetyl-CoA reductase activity [GO:0018454]; amyloid-beta binding [GO:0001540]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estrogen receptor binding [GO:0030331]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; steroid binding [GO:0005496]; testosterone dehydrogenase [NAD(P)] activity [GO:0030283]; tRNA binding [GO:0000049]; cell aging [GO:0007569]; Leydig cell differentiation [GO:0033327]; mitochondrial tRNA 3'-end processing [GO:1990180]; mitochondrial tRNA 5'-end processing [GO:0097745]; mitochondrial tRNA methylation [GO:0070901]; protein homotetramerization [GO:0051289]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cell aging [GO:0007569]; Leydig cell differentiation [GO:0033327]; mitochondrial tRNA 3'-end processing [GO:1990180]; mitochondrial tRNA 5'-end processing [GO:0097745]; mitochondrial tRNA methylation [GO:0070901]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	mitochondrial ribonuclease P complex [GO:0030678]; mitochondrion [GO:0005739]		3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity [GO:0047015]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; acetoacetyl-CoA reductase activity [GO:0018454]; amyloid-beta binding [GO:0001540]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estrogen receptor binding [GO:0030331]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; steroid binding [GO:0005496]; testosterone dehydrogenase [NAD(P)] activity [GO:0030283]; tRNA binding [GO:0000049]	L-malate dehydrogenase activity [GO:0030060]
d1e3wd__d4ijub1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial ribonuclease P complex [GO:0030678]; mitochondrion [GO:0005739]; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity [GO:0047015]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; acetoacetyl-CoA reductase activity [GO:0018454]; amyloid-beta binding [GO:0001540]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estrogen receptor binding [GO:0030331]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; steroid binding [GO:0005496]; testosterone dehydrogenase [NAD(P)] activity [GO:0030283]; tRNA binding [GO:0000049]; cell aging [GO:0007569]; Leydig cell differentiation [GO:0033327]; mitochondrial tRNA 3'-end processing [GO:1990180]; mitochondrial tRNA 5'-end processing [GO:0097745]; mitochondrial tRNA methylation [GO:0070901]; protein homotetramerization [GO:0051289]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cell aging [GO:0007569]; Leydig cell differentiation [GO:0033327]; mitochondrial tRNA 3'-end processing [GO:1990180]; mitochondrial tRNA 5'-end processing [GO:0097745]; mitochondrial tRNA methylation [GO:0070901]; protein homotetramerization [GO:0051289]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	mitochondrial ribonuclease P complex [GO:0030678]; mitochondrion [GO:0005739]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity [GO:0047015]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; acetoacetyl-CoA reductase activity [GO:0018454]; amyloid-beta binding [GO:0001540]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estrogen receptor binding [GO:0030331]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; steroid binding [GO:0005496]; testosterone dehydrogenase [NAD(P)] activity [GO:0030283]; tRNA binding [GO:0000049]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d1e3ya__d3ygsc___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d1e3za2_d1ta3b___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; enzyme inhibitor activity [GO:0004857]; carbohydrate metabolic process [GO:0005975]; defense response to fungus [GO:0050832]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; defense response to fungus [GO:0050832]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	enzyme inhibitor activity [GO:0004857]
d1e40a1_d1g94a1__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d1e41a__d1a1za___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]
d1e41a__d2a9ia___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]; ATP binding [GO:0005524]; interleukin-1 receptor binding [GO:0005149]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of smooth muscle cell proliferation [GO:0048661]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of smooth muscle cell proliferation [GO:0048661]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	ATP binding [GO:0005524]; interleukin-1 receptor binding [GO:0005149]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d1e42a1_d1om9a___1	Metazoa	Metazoa	Chordata	Chordata	AP-2 adaptor complex [GO:0030122]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]; clathrin binding [GO:0030276]; protein-containing complex binding [GO:0044877]; signal sequence binding [GO:0005048]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; coronary vasculature development [GO:0060976]; ephrin receptor signaling pathway [GO:0048013]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; membrane organization [GO:0061024]; negative regulation of neuron death [GO:1901215]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein localization to membrane [GO:1905477]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; regulation of defense response to virus by virus [GO:0050690]; synaptic vesicle endocytosis [GO:0048488]; ventricular septum development [GO:0003281]; vesicle-mediated transport [GO:0016192]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; coronary vasculature development [GO:0060976]; ephrin receptor signaling pathway [GO:0048013]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; membrane organization [GO:0061024]; negative regulation of neuron death [GO:1901215]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein localization to membrane [GO:1905477]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; regulation of defense response to virus by virus [GO:0050690]; synaptic vesicle endocytosis [GO:0048488]; ventricular septum development [GO:0003281]; vesicle-mediated transport [GO:0016192]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	AP-2 adaptor complex [GO:0030122]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	clathrin binding [GO:0030276]; protein-containing complex binding [GO:0044877]; signal sequence binding [GO:0005048]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]
d1e48p__d1dzxp___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]	aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]
d1e49p__d4c25a1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	L-fuculose-phosphate aldolase activity [GO:0008738]; metal ion binding [GO:0046872]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]		cytosol [GO:0005829]		aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]	L-fuculose-phosphate aldolase activity [GO:0008738]; metal ion binding [GO:0046872]
d1e4ap__d2v9ea___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]
d1e4ea2_d4c5ca2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1e4ia__d3baxa2__1		Metazoa	Firmicutes	Chordata	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cellulose catabolic process [GO:0030245]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1e4ja2_d2exwd2__1	Metazoa		Chordata	Proteobacteria	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; IgG binding [GO:0019864]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	immune response [GO:0006955]; neutrophil degranulation [GO:0043312]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	IgG binding [GO:0019864]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1e4ka2_d1hxmc1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	transmembrane signaling receptor activity [GO:0004888]
d1e4kc2_d1zxqa2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cleavage furrow [GO:0032154]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; uropod [GO:0001931]; integrin binding [GO:0005178]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; extracellular matrix organization [GO:0030198]; regulation of immune response [GO:0050776]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; extracellular matrix organization [GO:0030198]; regulation of immune response [GO:0050776]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cleavage furrow [GO:0032154]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; uropod [GO:0001931]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	integrin binding [GO:0005178]
d1e4mm__d1e1fb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	vacuole [GO:0005773]	chloroplast [GO:0009507]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]	beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]
d1e4na__d1ktca2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	cytoplasm [GO:0005737]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]; lysosome [GO:0005764]	beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]
d1e4nb__d1h49b___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]	beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]
d1e4wh1_d3vxqe1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1e4wl2_d3e3qw___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1e4xi1_d3bova___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1e4xl1_d3u79c___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1e4xl2_d2fjha1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]
d1e4xm1_d5tpsb2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1e4xm2_d3wxvh___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]; adipokinetic hormone receptor activity [GO:0097003]; adiponectin binding [GO:0055100]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; leptin-mediated signaling pathway [GO:0033210]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid metabolic process [GO:0019216]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; leptin-mediated signaling pathway [GO:0033210]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid metabolic process [GO:0019216]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	adipokinetic hormone receptor activity [GO:0097003]; adiponectin binding [GO:0055100]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]
d1e50c__d5aola___1	Metazoa	Metazoa	Chordata	Chordata	core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; chondrocyte differentiation [GO:0002062]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; peripheral nervous system neuron development [GO:0048935]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytokine-mediated signaling pathway [GO:0001959]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of keratinocyte differentiation [GO:0045616]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of myeloid cell differentiation [GO:0045637]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of Wnt signaling pathway [GO:0030111]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	chondrocyte differentiation [GO:0002062]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; peripheral nervous system neuron development [GO:0048935]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytokine-mediated signaling pathway [GO:0001959]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of keratinocyte differentiation [GO:0045616]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of myeloid cell differentiation [GO:0045637]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of Wnt signaling pathway [GO:0030111]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1e55a__d4b3kb___1	Viridiplantae		Streptophyta	Firmicutes	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	carbohydrate metabolic process [GO:0005975]	chloroplast [GO:0009507]		beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1e55b__d1kxqb2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	carbohydrate catabolic process [GO:0016052]	chloroplast [GO:0009507]	extracellular space [GO:0005615]	beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1e57b__d1e57a___1					T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]			T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1e57c__d2fz1a___1					T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]			T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1e5ba__d1hehc___1			Actinobacteria	Actinobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]	endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]
d1e5ba__d1tf4a2__1			Actinobacteria	Actinobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]; xylan catabolic process [GO:0045493]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]			endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d1e5db1_d1gg5b___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; respiratory electron transport chain [GO:0022904]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	respiratory electron transport chain [GO:0022904]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d1e5db2_d4dilb1__1			Proteobacteria	Thermotogae	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; respiratory electron transport chain [GO:0022904]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	respiratory electron transport chain [GO:0022904]				electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1e5ea__d2ch1a1__1		Metazoa		Arthropoda	cytoplasm [GO:0005737]; carbon-sulfur lyase activity [GO:0016846]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	peroxisome [GO:0005777]; alanine-glyoxylate transaminase activity [GO:0008453]; serine-pyruvate transaminase activity [GO:0004760]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]	transsulfuration [GO:0019346]	glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]	cytoplasm [GO:0005737]	peroxisome [GO:0005777]	carbon-sulfur lyase activity [GO:0016846]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]	alanine-glyoxylate transaminase activity [GO:0008453]; serine-pyruvate transaminase activity [GO:0004760]
d1e5eb__d1amra___1				Proteobacteria	cytoplasm [GO:0005737]; carbon-sulfur lyase activity [GO:0016846]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	transsulfuration [GO:0019346]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbon-sulfur lyase activity [GO:0016846]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1e5fa__d5x2wd___1				Proteobacteria	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	transsulfuration [GO:0019346]	transsulfuration [GO:0019346]			methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d1e5qc2_d1zyap2__1	Fungi		Ascomycota		saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]; lysine biosynthetic process via aminoadipic acid [GO:0019878]		lysine biosynthetic process via aminoadipic acid [GO:0019878]				saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]	
d1e5qg2_d3pyld2__1	Fungi		Ascomycota		saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]; lysine biosynthetic process via aminoadipic acid [GO:0019878]		lysine biosynthetic process via aminoadipic acid [GO:0019878]				saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]	
d1e5ta1_d4bcda1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d1e5ui1_d1cwva1__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell surface [GO:0009986]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]		
d1e5ui1_d2zqkb1__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]		
d1e5va1_d1cz4a1__1			Proteobacteria	Euryarchaeota	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	ATP binding [GO:0005524]; hydrolase activity [GO:0016787]			periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	ATP binding [GO:0005524]; hydrolase activity [GO:0016787]
d1e5wa1_d2d11c1__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; invadopodium [GO:0071437]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; cell adhesion molecule binding [GO:0050839]; double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]; cellular response to testosterone stimulus [GO:0071394]; establishment of endothelial barrier [GO:0061028]; establishment of epithelial cell apical/basal polarity [GO:0045198]; gland morphogenesis [GO:0022612]; immunological synapse formation [GO:0001771]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein localization to early endosome [GO:1902966]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of lymphocyte migration [GO:2000401]; regulation of organelle assembly [GO:1902115]; T cell aggregation [GO:0070489]; T cell migration [GO:0072678]; T cell proliferation [GO:0042098]; viral process [GO:0016032]	apical plasma membrane [GO:0016324]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]; protein-containing complex assembly [GO:0065003]	cellular response to testosterone stimulus [GO:0071394]; establishment of endothelial barrier [GO:0061028]; establishment of epithelial cell apical/basal polarity [GO:0045198]; gland morphogenesis [GO:0022612]; immunological synapse formation [GO:0001771]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein localization to early endosome [GO:1902966]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of lymphocyte migration [GO:2000401]; regulation of organelle assembly [GO:1902115]; T cell aggregation [GO:0070489]; T cell migration [GO:0072678]; T cell proliferation [GO:0042098]; viral process [GO:0016032]	protein-containing complex assembly [GO:0065003]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; invadopodium [GO:0071437]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; uropod [GO:0001931]; vesicle [GO:0031982]	apical plasma membrane [GO:0016324]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	actin binding [GO:0003779]; cell adhesion molecule binding [GO:0050839]; double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]	beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]
d1e5wa2_d5nqhc___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; invadopodium [GO:0071437]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; cell adhesion molecule binding [GO:0050839]; double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]; cellular response to testosterone stimulus [GO:0071394]; establishment of endothelial barrier [GO:0061028]; establishment of epithelial cell apical/basal polarity [GO:0045198]; gland morphogenesis [GO:0022612]; immunological synapse formation [GO:0001771]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein localization to early endosome [GO:1902966]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of lymphocyte migration [GO:2000401]; regulation of organelle assembly [GO:1902115]; T cell aggregation [GO:0070489]; T cell migration [GO:0072678]; T cell proliferation [GO:0042098]; viral process [GO:0016032]	cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; growth cone [GO:0030426]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; lamellipodium [GO:0030027]; main axon [GO:0044304]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; proline-rich region binding [GO:0070064]; protein-containing complex binding [GO:0044877]; tau protein binding [GO:0048156]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone H4 acetylation [GO:0043967]; negative regulation of cell growth [GO:0030308]; negative regulation of thymidylate synthase biosynthetic process [GO:0050760]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein secretion [GO:0050714]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; response to iron ion [GO:0010039]; signal transduction [GO:0007165]	cellular response to testosterone stimulus [GO:0071394]; establishment of endothelial barrier [GO:0061028]; establishment of epithelial cell apical/basal polarity [GO:0045198]; gland morphogenesis [GO:0022612]; immunological synapse formation [GO:0001771]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein localization to early endosome [GO:1902966]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of lymphocyte migration [GO:2000401]; regulation of organelle assembly [GO:1902115]; T cell aggregation [GO:0070489]; T cell migration [GO:0072678]; T cell proliferation [GO:0042098]; viral process [GO:0016032]	apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone H4 acetylation [GO:0043967]; negative regulation of cell growth [GO:0030308]; negative regulation of thymidylate synthase biosynthetic process [GO:0050760]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein secretion [GO:0050714]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to iron ion [GO:0010039]; signal transduction [GO:0007165]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; invadopodium [GO:0071437]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; uropod [GO:0001931]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; growth cone [GO:0030426]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; lamellipodium [GO:0030027]; main axon [GO:0044304]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	actin binding [GO:0003779]; cell adhesion molecule binding [GO:0050839]; double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]	amyloid-beta binding [GO:0001540]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; proline-rich region binding [GO:0070064]; protein-containing complex binding [GO:0044877]; tau protein binding [GO:0048156]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d1e5wa3_d1kjta___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; invadopodium [GO:0071437]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; cell adhesion molecule binding [GO:0050839]; double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]; cellular response to testosterone stimulus [GO:0071394]; establishment of endothelial barrier [GO:0061028]; establishment of epithelial cell apical/basal polarity [GO:0045198]; gland morphogenesis [GO:0022612]; immunological synapse formation [GO:0001771]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein localization to early endosome [GO:1902966]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of lymphocyte migration [GO:2000401]; regulation of organelle assembly [GO:1902115]; T cell aggregation [GO:0070489]; T cell migration [GO:0072678]; T cell proliferation [GO:0042098]; viral process [GO:0016032]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein transport [GO:0015031]	cellular response to testosterone stimulus [GO:0071394]; establishment of endothelial barrier [GO:0061028]; establishment of epithelial cell apical/basal polarity [GO:0045198]; gland morphogenesis [GO:0022612]; immunological synapse formation [GO:0001771]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein localization to early endosome [GO:1902966]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of lymphocyte migration [GO:2000401]; regulation of organelle assembly [GO:1902115]; T cell aggregation [GO:0070489]; T cell migration [GO:0072678]; T cell proliferation [GO:0042098]; viral process [GO:0016032]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein transport [GO:0015031]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; invadopodium [GO:0071437]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; uropod [GO:0001931]; vesicle [GO:0031982]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]	actin binding [GO:0003779]; cell adhesion molecule binding [GO:0050839]; double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]	beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d1e5ya__d1j9rc1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1e5yd__d1ibyc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	metal ion binding [GO:0046872]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1e5zb__d1kyab3__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1e5zc__d1l9tb2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1e5zd__d1a8za___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1e60c1_d1dmsa1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]
d1e64a1_d1ewya1__1			Cyanobacteria	Cyanobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	phycobilisome [GO:0030089]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d1e64a1_d2vnka1__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1e65b__d7paza___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1e65c__d1kyac1__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1e67a__d1adwa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1e67c__d1ilsb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1e67d__d1l9rc2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1e6ab__d3r5vb___1	Fungi		Ascomycota	Euryarchaeota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1e6cb__d3ziak2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	ATP synthesis coupled proton transport [GO:0015986]	cytoplasm [GO:0005737]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e6jh1_d4h0hb2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d1e6jh2_d3h8na1__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; MHC class Ib protein binding [GO:0023029]; innate immune response [GO:0045087]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	innate immune response [GO:0045087]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	MHC class Ib protein binding [GO:0023029]
d1e6jl1_d4l29r1__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1e6ma1_d3rvla___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]	cytosol [GO:0005829]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d1e6oh1_d1lega1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1e6oh2_d1k8ib1__1		Metazoa		Chordata		endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; MHC class II protein complex binding [GO:0023026]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; chaperone cofactor-dependent protein refolding [GO:0051085]		adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; chaperone cofactor-dependent protein refolding [GO:0051085]		endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]		MHC class II protein complex binding [GO:0023026]
d1e6ol1_d4lvnb1__1				Apicomplexa		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]						metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1e6qm__d5okra___1	Viridiplantae		Streptophyta	Firmicutes	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	6-phospho-beta-galactosidase activity [GO:0033920]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	vacuole [GO:0005773]		glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]	6-phospho-beta-galactosidase activity [GO:0033920]
d1e6rb3_d2o92a2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	carbohydrate metabolic process [GO:0005975]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]
d1e6sm__d3dyma3__1	Viridiplantae		Streptophyta	Proteobacteria	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	vacuole [GO:0005773]	beta-galactosidase complex [GO:0009341]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1e6tb__d1zdha___1						T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]		regulation of translation [GO:0006417]		T=3 icosahedral viral capsid [GO:0039617]		identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1e6ua__d2iypa1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; GDP-L-fucose synthase activity [GO:0050577]; isomerase activity [GO:0016853]; NADP+ binding [GO:0070401]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; colanic acid biosynthetic process [GO:0009242]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; colanic acid biosynthetic process [GO:0009242]	D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]		GDP-L-fucose synthase activity [GO:0050577]; isomerase activity [GO:0016853]; NADP+ binding [GO:0070401]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]
d1e6va1_d5n1qe2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]; methanogenesis [GO:0015948]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	cytoplasm [GO:0005737]		coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]
d1e6ve1_d3m30b2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]; methanogenesis [GO:0015948]	cytoplasm [GO:0005737]; coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]
d1e6ve1_d5n2ab2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]; methanogenesis [GO:0015948]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	cytoplasm [GO:0005737]		coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]
d1e70m__d3h54b1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	vacuole [GO:0005773]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d1e78a1_d2xw1b3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1e78a2_d1tf0a3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1e79a1_d2v7qa3__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e79c2_d5ik2m1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e79d3_d2vp4b___1	Metazoa	Metazoa	Chordata	Arthropoda	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	ATP synthesis coupled proton transport [GO:0015986]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]
d1e79e2_d5ik2j1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1e79e3_d2pt7f___1	Metazoa		Chordata	Proteobacteria	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	type IV secretion system complex [GO:0043684]; nucleotide binding [GO:0000166]; secretion by the type IV secretion system [GO:0044097]	ATP synthesis coupled proton transport [GO:0015986]	secretion by the type IV secretion system [GO:0044097]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	type IV secretion system complex [GO:0043684]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	nucleotide binding [GO:0000166]
d1e7aa1_d5dbya1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1e7aa2_d5dqfa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1e7ab2_d5iiha2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1e7ba1_d3lu7b2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1e7bb2_d5ij5a3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1e7ea1_d4k71a2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1e7ea2_d5otbc1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1e7fa1_d4s1ya2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1e7ha1_d4zbqa2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1e7ha2_d3v08a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1e7ja__d3nm9m___1	Metazoa	Metazoa	Arthropoda	Arthropoda	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]; chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]; chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]	AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]
d1e7la2_d2qnfb2__1					endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]					endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d1e7nb__d1okib2__1	Metazoa	Metazoa	Chordata	Chordata	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; camera-type eye development [GO:0043010]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	camera-type eye development [GO:0043010]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d1e7pd3_d1jrza3__1			Proteobacteria	Proteobacteria	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	tricarboxylic acid cycle [GO:0006099]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	respirasome [GO:0070469]	outer membrane-bounded periplasmic space [GO:0030288]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]	electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]
d1e7pe2_d1v97b2__1		Metazoa	Proteobacteria	Chordata	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	tricarboxylic acid cycle [GO:0006099]	xanthine catabolic process [GO:0009115]	respirasome [GO:0070469]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1e7ph2_d1zcsa5__1			Proteobacteria		respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]		respirasome [GO:0070469]		2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]	
d1e7pk1_d3vr8b2__1		Metazoa	Proteobacteria	Nematoda (roundworms)	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d1e7pk2_d3sr6a1__1		Metazoa	Proteobacteria	Chordata	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	tricarboxylic acid cycle [GO:0006099]	xanthine catabolic process [GO:0009115]	respirasome [GO:0070469]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1e7pk2_d5h57c___1		Viridiplantae	Proteobacteria	Streptophyta	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; etioplast stroma [GO:0009578]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; electron transport chain [GO:0022900]	tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]	respirasome [GO:0070469]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; etioplast stroma [GO:0009578]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1e7qa__d1zbqd___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; GDP-L-fucose synthase activity [GO:0050577]; isomerase activity [GO:0016853]; NADP+ binding [GO:0070401]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; colanic acid biosynthetic process [GO:0009242]	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]; alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; colanic acid biosynthetic process [GO:0009242]	alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	GDP-L-fucose synthase activity [GO:0050577]; isomerase activity [GO:0016853]; NADP+ binding [GO:0070401]	17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]
d1e7ra__d1qg6c___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; GDP-L-fucose synthase activity [GO:0050577]; isomerase activity [GO:0016853]; NADP+ binding [GO:0070401]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; colanic acid biosynthetic process [GO:0009242]	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; colanic acid biosynthetic process [GO:0009242]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	GDP-L-fucose synthase activity [GO:0050577]; isomerase activity [GO:0016853]; NADP+ binding [GO:0070401]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]
d1e80e__d1t7ib___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1e82e__d3qihb___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1e83a__d3nmjb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1e87a__d3g81a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cellular response to drug [GO:0035690]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cellular response to drug [GO:0035690]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1e87a__d3ikpa2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cellular response to drug [GO:0035690]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cellular response to drug [GO:0035690]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1e89a1_d2oqib2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1e89b1_d4lkoa2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1e8aa__d1juoa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]; action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]
d1e8da1_d1xrqa___1	Viridiplantae		Streptophyta	Euryarchaeota	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	aminopeptidase activity [GO:0004177]					aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	aminopeptidase activity [GO:0004177]
d1e8db1_d3d2bb___1	Viridiplantae		Streptophyta	Firmicutes	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d1e8fa1_d1w1kb1__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1e8ga1_d1w1la1__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1e8hb1_d1qltb1__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1e8ia__d3zhgb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cellular response to drug [GO:0035690]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; (1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	cellular response to drug [GO:0035690]	detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]	(1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]
d1e8ib__d4gk1e___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cellular response to drug [GO:0035690]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	cellular response to drug [GO:0035690]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d1e8ma2_d1h2xa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d1e8ma2_d3aind___1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]
d1e8ta__d1v0ed1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	virus tail, fiber [GO:0098024]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]
d1e8va__d4gdif___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1e8vb__d2hu4e___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1e94c__d4no6l___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1e94d__d4hnzi1__1			Proteobacteria		cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; HslUV protease complex [GO:0009376]; kinetoplast [GO:0020023]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nuclear lumen [GO:0031981]; proteasome core complex [GO:0005839]; ATP-dependent peptidase activity [GO:0004176]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; mitochondrial DNA inheritance [GO:0033955]; mitochondrial DNA replication [GO:0006264]; proteolysis involved in cellular protein catabolic process [GO:0051603]; rolling circle DNA replication [GO:0070581]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	mitochondrial DNA inheritance [GO:0033955]; mitochondrial DNA replication [GO:0006264]; proteolysis involved in cellular protein catabolic process [GO:0051603]; rolling circle DNA replication [GO:0070581]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; HslUV protease complex [GO:0009376]; kinetoplast [GO:0020023]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nuclear lumen [GO:0031981]; proteasome core complex [GO:0005839]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]	ATP-dependent peptidase activity [GO:0004176]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1e9ca__d3b13d___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627]; thymidine biosynthetic process [GO:0046105]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; histone deacetylase binding [GO:0042826]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cell-matrix adhesion [GO:0007160]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627]; thymidine biosynthetic process [GO:0046105]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; histone deacetylase binding [GO:0042826]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]
d1e9da__d1fp6d___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627]; thymidine biosynthetic process [GO:0046105]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627]; thymidine biosynthetic process [GO:0046105]	nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1e9ga__d1obwa___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; membrane [GO:0016020]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; membrane [GO:0016020]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]
d1e9hb1_d1kxua1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cyclin-dependent protein kinase activating kinase holoenzyme complex [GO:0019907]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIIH holo complex [GO:0005675]; transcription factor TFIIK complex [GO:0070985]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; 7-methylguanosine mRNA capping [GO:0006370]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein stabilization [GO:0050821]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase I promoter [GO:0006361]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription-coupled nucleotide-excision repair [GO:0006283]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	7-methylguanosine mRNA capping [GO:0006370]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein stabilization [GO:0050821]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	cyclin-dependent protein kinase activating kinase holoenzyme complex [GO:0019907]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIIH holo complex [GO:0005675]; transcription factor TFIIK complex [GO:0070985]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]
d1e9hb2_d2uueb1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1e9ib1_d4zcwa2__1		Metazoa	Proteobacteria	Chordata	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1e9ib2_d1sjbd2__1			Proteobacteria	Actinobacteria	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	glycolytic process [GO:0006096]	menaquinone biosynthetic process [GO:0009234]	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d1e9ic2_d3r4ea1__1			Proteobacteria		cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	
d1e9la2_d1e6za3__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; rough endoplasmic reticulum lumen [GO:0048237]; beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; chitin catabolic process [GO:0006032]; inflammatory response [GO:0006954]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; inflammatory response [GO:0006954]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; rough endoplasmic reticulum lumen [GO:0048237]	extracellular region [GO:0005576]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]; chitin binding [GO:0008061]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1e9ma__d3sr6j1__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1e9qb__d1mfma___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1e9sf__d2ofwd___1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; conjugation [GO:0000746]	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	conjugation [GO:0000746]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	integral component of membrane [GO:0016021]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1ea9c1_d3do7a2__1		Metazoa	Firmicutes	Chordata	cyclomaltodextrinase activity [GO:0047798]; carbohydrate metabolic process [GO:0005975]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	carbohydrate metabolic process [GO:0005975]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]		centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	cyclomaltodextrinase activity [GO:0047798]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d1ea9c1_d3vgea1__1			Firmicutes	Crenarchaeota	cyclomaltodextrinase activity [GO:0047798]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]		cytoplasm [GO:0005737]	cyclomaltodextrinase activity [GO:0047798]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]
d1ea9c2_d1j0jb2__1			Firmicutes	Firmicutes	cyclomaltodextrinase activity [GO:0047798]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			cyclomaltodextrinase activity [GO:0047798]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1ea9c3_d1viwa2__1		Metazoa	Firmicutes	Arthropoda	cyclomaltodextrinase activity [GO:0047798]; carbohydrate metabolic process [GO:0005975]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]			cyclomaltodextrinase activity [GO:0047798]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1ea9c3_d5uhxa1__1			Firmicutes		cyclomaltodextrinase activity [GO:0047798]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				cyclomaltodextrinase activity [GO:0047798]	
d1ea9d1_d5b1cc___1			Firmicutes		cyclomaltodextrinase activity [GO:0047798]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cyclomaltodextrinase activity [GO:0047798]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1ea9d3_d1hjsc___1		Fungi	Firmicutes	Ascomycota	cyclomaltodextrinase activity [GO:0047798]; carbohydrate metabolic process [GO:0005975]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]; cell wall macromolecule catabolic process [GO:0016998]	carbohydrate metabolic process [GO:0005975]	cell wall macromolecule catabolic process [GO:0016998]			cyclomaltodextrinase activity [GO:0047798]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]
d1eaba__d1ciaa___1			Proteobacteria	Proteobacteria	pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	glycolytic process [GO:0006096]	response to antibiotic [GO:0046677]	pyruvate dehydrogenase complex [GO:0045254]		dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d1eaba__d2ii5f___1		Metazoa	Proteobacteria	Chordata	pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	glycolytic process [GO:0006096]		pyruvate dehydrogenase complex [GO:0045254]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1eaea__d1q23h___1			Proteobacteria	Proteobacteria	pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	glycolytic process [GO:0006096]	response to antibiotic [GO:0046677]	pyruvate dehydrogenase complex [GO:0045254]		dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d1eah3__d4y5zn___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1eaia__d5jbbs___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]
d1eaja__d1t04b2__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d1eajb__d5ihzd1__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d1eaka1_d1gxdb1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]	metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1eakb1_d2mzea1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]	angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1eaoa__d5aojb___1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1eapa2_d4ydlc1__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1eaua__d4y8ya___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d1eawa__d3zz4a1__1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1eawc__d2p94a___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1eayb__d4zyla___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	
d1eaza__d4ny0b3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; androgen metabolic process [GO:0008209]; B cell receptor signaling pathway [GO:0050853]; cellular response to hydrogen peroxide [GO:0070301]; establishment of protein localization [GO:0045184]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; Leydig cell differentiation [GO:0033327]; luteinization [GO:0001553]; multicellular organism growth [GO:0035264]; negative regulation of protein kinase B signaling [GO:0051898]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; ruffle organization [GO:0031529]; skeletal system morphogenesis [GO:0048705]; spermatogenesis [GO:0007283]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	androgen metabolic process [GO:0008209]; B cell receptor signaling pathway [GO:0050853]; cellular response to hydrogen peroxide [GO:0070301]; establishment of protein localization [GO:0045184]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; Leydig cell differentiation [GO:0033327]; luteinization [GO:0001553]; multicellular organism growth [GO:0035264]; negative regulation of protein kinase B signaling [GO:0051898]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; ruffle organization [GO:0031529]; skeletal system morphogenesis [GO:0048705]; spermatogenesis [GO:0007283]	angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]	PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]	actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]
d1eb8b1_d4ghwa___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]			aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	triglyceride lipase activity [GO:0004806]
d1eb9a1_d3visb___1	Viridiplantae		Streptophyta	Actinobacteria	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	metal ion binding [GO:0046872]					aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	metal ion binding [GO:0046872]
d1eb9b1_d1dt5d___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]			aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	triglyceride lipase activity [GO:0004806]
d1ebba__d4odid___1			Firmicutes	Apicomplexa		phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]				phosphoglycerate mutase activity [GO:0004619]
d1ebga1_d3uj2c2__1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1ebha2_d4gypa1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	D-glucarate catabolic process [GO:0042838]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d1ebkc__d2qi6b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ebkd__d3kdba___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ebpb1_d1kf9b2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	cell surface [GO:0009986]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth hormone receptor complex [GO:0070195]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; growth hormone receptor activity [GO:0004903]; identical protein binding [GO:0042802]; peptide hormone binding [GO:0017046]; proline-rich region binding [GO:0070064]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; activation of Janus kinase activity [GO:0042976]; activation of MAPK activity [GO:0000187]; cellular response to hormone stimulus [GO:0032870]; endocytosis [GO:0006897]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; hormone metabolic process [GO:0042445]; insulin-like growth factor receptor signaling pathway [GO:0048009]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; receptor internalization [GO:0031623]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of multicellular organism growth [GO:0040014]; response to cycloheximide [GO:0046898]; response to estradiol [GO:0032355]; taurine metabolic process [GO:0019530]	brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	activation of Janus kinase activity [GO:0042976]; activation of MAPK activity [GO:0000187]; cellular response to hormone stimulus [GO:0032870]; endocytosis [GO:0006897]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; hormone metabolic process [GO:0042445]; insulin-like growth factor receptor signaling pathway [GO:0048009]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; receptor internalization [GO:0031623]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of multicellular organism growth [GO:0040014]; response to cycloheximide [GO:0046898]; response to estradiol [GO:0032355]; taurine metabolic process [GO:0019530]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth hormone receptor complex [GO:0070195]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; growth hormone receptor activity [GO:0004903]; identical protein binding [GO:0042802]; peptide hormone binding [GO:0017046]; proline-rich region binding [GO:0070064]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]
d1ebta__d1ha7m___1	Metazoa		Mollusca	Cyanobacteria	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen transport [GO:0015671]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxygen transport [GO:0015671]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	
d1ebta__d4o4za___1	Metazoa	Metazoa	Mollusca	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen transport [GO:0015671]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]	oxygen transport [GO:0015671]	apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ebud2_d1e5qb2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; homoserine dehydrogenase activity [GO:0004412]; NADP binding [GO:0050661]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		homoserine dehydrogenase activity [GO:0004412]; NADP binding [GO:0050661]	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]
d1ebwa__d2qzxb___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; fungal biofilm matrix [GO:0062040]; fungal-type cell wall [GO:0009277]; aspartic-type endopeptidase activity [GO:0004190]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; fungal biofilm matrix [GO:0062040]; fungal-type cell wall [GO:0009277]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1ebya__d5p3ra___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1ebyb__d3nu3a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ec1b__d2pyna___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ec1b__d5oz8a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1ec3a__d1s6sb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d1ec3b__d5p7xa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1ec6a1_d2opva___1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; RNA binding [GO:0003723]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of cold-induced thermogenesis [GO:0120163]; regulation of RNA metabolic process [GO:0051252]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; DNA binding [GO:0003677]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to cytokine stimulus [GO:0071345]; miRNA metabolic process [GO:0010586]; mRNA catabolic process [GO:0006402]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of miRNA metabolic process [GO:2000628]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]	mRNA splicing, via spliceosome [GO:0000398]; negative regulation of cold-induced thermogenesis [GO:0120163]; regulation of RNA metabolic process [GO:0051252]	3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to cytokine stimulus [GO:0071345]; miRNA metabolic process [GO:0010586]; mRNA catabolic process [GO:0006402]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of miRNA metabolic process [GO:2000628]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]	nucleus [GO:0005634]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	RNA binding [GO:0003723]	DNA binding [GO:0003677]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]
d1ec6b1_d2ctja1__1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; RNA binding [GO:0003723]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of cold-induced thermogenesis [GO:0120163]; regulation of RNA metabolic process [GO:0051252]	cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]	mRNA splicing, via spliceosome [GO:0000398]; negative regulation of cold-induced thermogenesis [GO:0120163]; regulation of RNA metabolic process [GO:0051252]	cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]	nucleus [GO:0005634]	cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	RNA binding [GO:0003723]	cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]
d1ec7a1_d2qjja2__1			Proteobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	D-glucarate catabolic process [GO:0042838]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d1ec7c1_d3rite2__1			Proteobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]	D-glucarate catabolic process [GO:0042838]	catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]			glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d1ec8a2_d4il0f1__1			Proteobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; cellular catabolic process [GO:0044248]	D-glucarate catabolic process [GO:0042838]	cellular amino acid catabolic process [GO:0009063]; cellular catabolic process [GO:0044248]			glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]
d1ec8b2_d2fyma2__1			Proteobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	D-glucarate catabolic process [GO:0042838]	glycolytic process [GO:0006096]		cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1ec8d2_d1l8pb2__1		Fungi	Proteobacteria	Ascomycota	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	D-glucarate catabolic process [GO:0042838]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1ec9a1_d1bqga1__1			Proteobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	D-glucarate catabolic process [GO:0042838]	D-glucarate catabolic process [GO:0042838]			glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d1ec9a1_d5enla1__1		Fungi	Proteobacteria	Ascomycota	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	D-glucarate catabolic process [GO:0042838]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1ec9c2_d1jpma2__1			Proteobacteria	Firmicutes	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	D-glucarate catabolic process [GO:0042838]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]			glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d1ecba2_d1xffb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]
d1ecbc1_d1xtvc___1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]
d1ecbc2_d4qvmi___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ecda__d3gysb___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ecea__d1rp8a2__1		Viridiplantae	Actinobacteria	Streptophyta	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]		extracellular space [GO:0005615]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1eceb__d2vx6a___1			Actinobacteria		cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]				cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	
d1ecfa2_d4cr2b___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ecfb1_d4s2ua1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; ribose phosphate diphosphokinase activity [GO:0004749]
d1ecgb1_d3ozfa1__1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; xanthine phosphoribosyltransferase activity [GO:0000310]; GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; xanthine phosphoribosyltransferase activity [GO:0000310]
d1ecjc2_d5fgie___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ecjd1_d2h08b1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]
d1ecjd2_d2vdce3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	4 iron, 4 sulfur cluster binding [GO:0051539]; glutamate synthase (NADPH) activity [GO:0004355]; metal ion binding [GO:0046872]; L-glutamate biosynthetic process [GO:0097054]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	L-glutamate biosynthetic process [GO:0097054]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]	4 iron, 4 sulfur cluster binding [GO:0051539]; glutamate synthase (NADPH) activity [GO:0004355]; metal ion binding [GO:0046872]
d1ecpc__d4g41b1__1			Proteobacteria		cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]		cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]		cytosol [GO:0005829]; membrane [GO:0016020]		identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	
d1ecqa1_d3ujsa2__1		Metazoa	Proteobacteria	Chordata	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	D-glucarate catabolic process [GO:0042838]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1ecqa2_d1elsa2__1		Fungi	Proteobacteria	Ascomycota	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	D-glucarate catabolic process [GO:0042838]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1ecwa__d1mn8b___1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell late endosome membrane [GO:0044185]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral budding via host ESCRT complex [GO:0039702]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral budding via host ESCRT complex [GO:0039702]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]	host cell late endosome membrane [GO:0044185]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d1ecwa__d1tama___1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ed1a__d2f76x___1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral budding via host ESCRT complex [GO:0039702]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral budding via host ESCRT complex [GO:0039702]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d1ed3a1_d5j8ob1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		
d1ed3a2_d2ipka2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1ed3d2_d2bnqa2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	cytoplasm [GO:0005737]		
d1ed3d2_d2yf1a1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]			
d1ed8a__d1khlb___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1ed9a__d1khla___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1ed9b__d1alib___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1edba__d5kwja___1			Proteobacteria	Actinobacteria	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	cell wall [GO:0005618]; extracellular region [GO:0005576]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; extracellular region [GO:0005576]	haloalkane dehalogenase activity [GO:0018786]	diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]
d1edea__d1cija___1			Proteobacteria	Proteobacteria	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]			haloalkane dehalogenase activity [GO:0018786]	haloalkane dehalogenase activity [GO:0018786]
d1edea__d1xzea___1		Fungi	Proteobacteria	Ascomycota	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]			extracellular region [GO:0005576]	haloalkane dehalogenase activity [GO:0018786]	cutinase activity [GO:0050525]
d1edga__d3t08c3__1			Firmicutes	Proteobacteria	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	cellulase activity [GO:0008810]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1edha1_d3q2lb2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d1edha2_d4zmza2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d1edhb1_d4zmtb1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d1edhb2_d4zmoa2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d1edoa__d4wlvd1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	fatty acid biosynthetic process [GO:0006633]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d1edta__d4cd5a___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]; carbohydrate metabolic process [GO:0005975]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; substituted mannan metabolic process [GO:0006080]	carbohydrate metabolic process [GO:0005975]	substituted mannan metabolic process [GO:0006080]	extracellular region [GO:0005576]		mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]
d1ee0a2_d4ddoa1__1	Viridiplantae		Streptophyta	Proteobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]			transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1ee0b2_d4c6wb2__1	Viridiplantae		Streptophyta		transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]		biosynthetic process [GO:0009058]				transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	
d1ee8b1_d2f5qa1__1			Deinococcus-Thermus	Firmicutes	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]			class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]
d1ee9a2_d1diga2__1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; folic acid-containing compound biosynthetic process [GO:0009396]; one-carbon metabolic process [GO:0006730]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity [GO:0004486]; 10-formyltetrahydrofolate biosynthetic process [GO:0009257]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; folic acid metabolic process [GO:0046655]; heart development [GO:0007507]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; one-carbon metabolic process [GO:0006730]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; serine family amino acid biosynthetic process [GO:0009070]; serine family amino acid metabolic process [GO:0009069]; somite development [GO:0061053]; tetrahydrofolate interconversion [GO:0035999]	folic acid-containing compound biosynthetic process [GO:0009396]; one-carbon metabolic process [GO:0006730]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	10-formyltetrahydrofolate biosynthetic process [GO:0009257]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; folic acid metabolic process [GO:0046655]; heart development [GO:0007507]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; one-carbon metabolic process [GO:0006730]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; serine family amino acid biosynthetic process [GO:0009070]; serine family amino acid metabolic process [GO:0009069]; somite development [GO:0061053]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]	methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity [GO:0004486]
d1eefd__d1tiif___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1eefh__d2rdhc1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1eefo__d4fnfh___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1eefp__d1ktkc1__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	toxin activity [GO:0090729]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1eeid__d1ha5d1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]		toxin activity [GO:0090729]
d1eeid__d1r4qk___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; negative regulation of translation [GO:0017148]	pathogenesis [GO:0009405]	negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1eeig__d1bcpk___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]		toxin activity [GO:0090729]
d1eeih__d3seba1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1eema1_d4ivfg2__1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]		cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]	
d1eena__d2cm7a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1eeqa__d1y0ld1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]	
d1eerc1_d1gh7a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; signaling receptor activity [GO:0038023]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-3 [GO:0036016]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-3-mediated signaling pathway [GO:0038156]; interleukin-5-mediated signaling pathway [GO:0038043]; MAPK cascade [GO:0000165]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]	brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	cellular protein metabolic process [GO:0044267]; cellular response to interleukin-3 [GO:0036016]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-3-mediated signaling pathway [GO:0038156]; interleukin-5-mediated signaling pathway [GO:0038043]; MAPK cascade [GO:0000165]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]	granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]	cytokine receptor activity [GO:0004896]; signaling receptor activity [GO:0038023]
d1eeub__d1nbqb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]; cadherin binding [GO:0045296]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618]; actomyosin structure organization [GO:0031032]; bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; establishment of endothelial intestinal barrier [GO:0090557]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to bicellular tight junction [GO:1902396]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of cytoskeleton organization [GO:0051493]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]; transforming growth factor beta receptor signaling pathway [GO:0007179]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	actomyosin structure organization [GO:0031032]; bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; establishment of endothelial intestinal barrier [GO:0090557]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to bicellular tight junction [GO:1902396]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of cytoskeleton organization [GO:0051493]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]; transforming growth factor beta receptor signaling pathway [GO:0007179]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]	antigen binding [GO:0003823]	cadherin binding [GO:0045296]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618]
d1eexb__d2d0od___1			Proteobacteria	Proteobacteria	propanediol dehydratase activity [GO:0050215]						propanediol dehydratase activity [GO:0050215]	
d1eeya1_d5j74a1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1eeyb__d5lbsl___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1eeza1_d5jpja1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1eezb__d5d96b1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; FAD binding [GO:0071949]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]; extracellular matrix assembly [GO:0085029]; negative regulation of macroautophagy [GO:0016242]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell redox homeostasis [GO:0045454]; extracellular matrix assembly [GO:0085029]; negative regulation of macroautophagy [GO:0016242]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	FAD binding [GO:0071949]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide isomerase activity [GO:0003756]
d1ef3a__d4jtda___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]
d1ef3b__d4g5db___1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytoplasm [GO:0005737]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]; prostaglandin biosynthetic process [GO:0001516]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	prostaglandin biosynthetic process [GO:0001516]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytoplasm [GO:0005737]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1ef9a__d4qijd___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; carboxy-lyase activity [GO:0016831]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; methylmalonyl-CoA decarboxylase activity [GO:0004492]; fatty acid beta-oxidation [GO:0006635]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; 1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; menaquinone biosynthetic process [GO:0009234]; protein hexamerization [GO:0034214]	fatty acid beta-oxidation [GO:0006635]	menaquinone biosynthetic process [GO:0009234]; protein hexamerization [GO:0034214]	cytosol [GO:0005829]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	carboxy-lyase activity [GO:0016831]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; methylmalonyl-CoA decarboxylase activity [GO:0004492]	1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]
d1efca1_d3vmfa2__1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1efcb1_d1yijb1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	translation [GO:0006412]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	ribosome [GO:0005840]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1efcb2_d3p3mc3__1			Proteobacteria		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	
d1efcb3_d1adea___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; 'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d1efdn__d4nd8c___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	nitrogen fixation [GO:0009399]	outer membrane-bounded periplasmic space [GO:0030288]	molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1efga1_d2zita2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]			cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d1efga3_d2i2pe1__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	
d1efga4_d3j3az3__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	
d1efih__d1fnud1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1efrb1_d5hkkn3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1efrb2_d2hldx1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1efrb2_d3j9tc1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	ATP synthesis coupled proton transport [GO:0015986]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]
d1efrc3_d1nksa___1	Metazoa		Chordata	Crenarchaeota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cytoplasm [GO:0005737]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]
d1efre1_d3tivb3__1	Metazoa		Chordata	Euryarchaeota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1efre3_d5hkkf2__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1efrf1_d2qe7d3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1efrf3_d2afhf___1	Metazoa		Chordata	Proteobacteria	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	ATP synthesis coupled proton transport [GO:0015986]	nitrogen fixation [GO:0009399]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	molybdenum-iron nitrogenase complex [GO:0016612]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1efta1_d1jnya1__1			Deinococcus-Thermus	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1efta2_d3cw2a3__1			Deinococcus-Thermus	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1efua1_d4j0qe2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1efua2_d3p3me3__1			Proteobacteria		cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		cytosol [GO:0005829]; plasma membrane [GO:0005886]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	
d1efua2_d4m0lf3__1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1efwa1_d1e1oa1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	aspartyl-tRNA aminoacylation [GO:0006422]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]
d1efwa2_d1eqrb2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	aspartyl-tRNA aminoacylation [GO:0006422]	aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]
d1efwa2_d2p8ta2__1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]	aspartyl-tRNA aminoacylation [GO:0006422]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]
d1efxa1_d4i1nb1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d1efxa2_d5ujta1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1efxb2_d1d6vl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1efxe1_d1p4il___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1eg1a__d1fx5a___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1eg1c__d4cela___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d1eg4a1_d2lvia___1	Metazoa	Viridiplantae	Chordata	Streptophyta	basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; contractile ring [GO:0070938]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystroglycan complex [GO:0016011]; dystrophin-associated glycoprotein complex [GO:0016010]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; node of Ranvier [GO:0033268]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]; actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; calcium ion binding [GO:0005509]; dystroglycan binding [GO:0002162]; laminin-1 binding [GO:0043237]; SH2 domain binding [GO:0042169]; structural constituent of muscle [GO:0008307]; tubulin binding [GO:0015631]; vinculin binding [GO:0017166]; virus receptor activity [GO:0001618]; aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; extracellular matrix organization [GO:0030198]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of embryonic cell shape [GO:0016476]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; skeletal muscle tissue regeneration [GO:0043403]	calcium ion binding [GO:0005509]	aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; extracellular matrix organization [GO:0030198]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of embryonic cell shape [GO:0016476]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; skeletal muscle tissue regeneration [GO:0043403]		basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; contractile ring [GO:0070938]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystroglycan complex [GO:0016011]; dystrophin-associated glycoprotein complex [GO:0016010]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; node of Ranvier [GO:0033268]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]		actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; calcium ion binding [GO:0005509]; dystroglycan binding [GO:0002162]; laminin-1 binding [GO:0043237]; SH2 domain binding [GO:0042169]; structural constituent of muscle [GO:0008307]; tubulin binding [GO:0015631]; vinculin binding [GO:0017166]; virus receptor activity [GO:0001618]	calcium ion binding [GO:0005509]
d1eg4a1_d3bunb1__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; contractile ring [GO:0070938]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystroglycan complex [GO:0016011]; dystrophin-associated glycoprotein complex [GO:0016010]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; node of Ranvier [GO:0033268]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]; actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; calcium ion binding [GO:0005509]; dystroglycan binding [GO:0002162]; laminin-1 binding [GO:0043237]; SH2 domain binding [GO:0042169]; structural constituent of muscle [GO:0008307]; tubulin binding [GO:0015631]; vinculin binding [GO:0017166]; virus receptor activity [GO:0001618]; aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; extracellular matrix organization [GO:0030198]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of embryonic cell shape [GO:0016476]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; skeletal muscle tissue regeneration [GO:0043403]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; extracellular matrix organization [GO:0030198]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of embryonic cell shape [GO:0016476]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; skeletal muscle tissue regeneration [GO:0043403]	cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; contractile ring [GO:0070938]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystroglycan complex [GO:0016011]; dystrophin-associated glycoprotein complex [GO:0016010]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; node of Ranvier [GO:0033268]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; calcium ion binding [GO:0005509]; dystroglycan binding [GO:0002162]; laminin-1 binding [GO:0043237]; SH2 domain binding [GO:0042169]; structural constituent of muscle [GO:0008307]; tubulin binding [GO:0015631]; vinculin binding [GO:0017166]; virus receptor activity [GO:0001618]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]
d1eg4a2_d1b47b1__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; contractile ring [GO:0070938]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystroglycan complex [GO:0016011]; dystrophin-associated glycoprotein complex [GO:0016010]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; node of Ranvier [GO:0033268]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]; actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; calcium ion binding [GO:0005509]; dystroglycan binding [GO:0002162]; laminin-1 binding [GO:0043237]; SH2 domain binding [GO:0042169]; structural constituent of muscle [GO:0008307]; tubulin binding [GO:0015631]; vinculin binding [GO:0017166]; virus receptor activity [GO:0001618]; aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; extracellular matrix organization [GO:0030198]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of embryonic cell shape [GO:0016476]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; skeletal muscle tissue regeneration [GO:0043403]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; extracellular matrix organization [GO:0030198]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of embryonic cell shape [GO:0016476]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; skeletal muscle tissue regeneration [GO:0043403]	cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; contractile ring [GO:0070938]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystroglycan complex [GO:0016011]; dystrophin-associated glycoprotein complex [GO:0016010]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; node of Ranvier [GO:0033268]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; calcium ion binding [GO:0005509]; dystroglycan binding [GO:0002162]; laminin-1 binding [GO:0043237]; SH2 domain binding [GO:0042169]; structural constituent of muscle [GO:0008307]; tubulin binding [GO:0015631]; vinculin binding [GO:0017166]; virus receptor activity [GO:0001618]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]
d1eg7b__d1gina___1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; 'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	tetrahydrofolate interconversion [GO:0035999]	'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]	adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d1eg9a2_d5c9ya___1		Viridiplantae	Proteobacteria	Streptophyta	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]; abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]		cytosol [GO:0005829]	dioxygenase activity [GO:0051213]	abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]
d1egcb1_d1udyd1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]
d1egcd1_d2a1tb1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]	electron transfer activity [GO:0009055]
d1egcd1_d2zafd1__1	Metazoa	Fungi	Chordata	Ascomycota	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d1egdb1_d1egea1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]
d1egdc1_d2c12c1__1	Metazoa	Fungi	Chordata	Ascomycota	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d1egdd1_d1ws9b1__1	Metazoa		Chordata	Deinococcus-Thermus	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]		axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d1egec1_d5k3ja2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	peroxisome [GO:0005777]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]	acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]
d1egha__d1m9nb1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1eghb__d1jdbk2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1eghc__d1oz0b1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1eghd__d1ce8g2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1eghd__d1vmda1__1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	methylglyoxal synthase activity [GO:0008929]
d1eghe__d1c3oa2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1egja__d5dc0a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]
d1egjh2_d1nc4a1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1egjh2_d1plgl2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	metal ion binding [GO:0046872]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d1egma__d1reqd1__1			Proteobacteria	Actinobacteria	propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]					propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d1egml__d4reqb1__1			Proteobacteria	Actinobacteria	propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]					propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d1egqa__d3qtlc___1	Fungi		Ascomycota	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1egua1_d1hmwa1__1			Firmicutes	Bacteroidetes	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]
d1egua1_d1hv6a___1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	periplasmic space [GO:0042597]; lyase activity [GO:0016829]	carbohydrate metabolic process [GO:0005975]		cell wall [GO:0005618]; extracellular region [GO:0005576]	periplasmic space [GO:0042597]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	lyase activity [GO:0016829]
d1egua3_d1xsia2__1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1egva__d5reqd1__1			Proteobacteria	Actinobacteria	propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]					propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d1egya__d3a4ga___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; erythromycin biosynthetic process [GO:1901115]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	erythromycin biosynthetic process [GO:1901115]; oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1egza__d1eqpa___1		Fungi	Proteobacteria	Ascomycota	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]; cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	cellulose catabolic process [GO:0030245]	cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]
d1egzb__d2nt1b2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	cellulose catabolic process [GO:0030245]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1eh0a__d3zpia___1				Actinobacteria		heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]		macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]				heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1eh2a__d1c07a___1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]; clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]; clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]
d1eh3a__d3cr9a2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]; specific granule [GO:0042581]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d1eh3a__d4ykia___1	Metazoa	Metazoa	Chordata	Ctenophora (ctenophores)	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ionotropic glutamate receptor activity [GO:0004970]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	ionotropic glutamate receptor activity [GO:0004970]
d1eh6a1_d3kzza2__1	Metazoa		Chordata		membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; metal ion binding [GO:0046872]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; methyltransferase activity [GO:0008168]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of double-strand break repair [GO:2000781]		DNA dealkylation involved in DNA repair [GO:0006307]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of double-strand break repair [GO:2000781]		membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; metal ion binding [GO:0046872]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; methyltransferase activity [GO:0008168]	
d1eh9a3_d1g94a2__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d1eh9a3_d3ahyd___1		Fungi	Crenarchaeota	Ascomycota	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	beta-glucosidase activity [GO:0008422]
d1ehaa1_d1cxia1__1			Crenarchaeota	Firmicutes	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1ehaa2_d4hoxa2__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d1ehfa__d4l54a___1	Fungi		Ascomycota	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1ehga__d3ofub___1	Fungi		Ascomycota	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1ehll1_d2r1wa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ehll2_d4ocrl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ehwa__d1mn7a___1	Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; cardiolipin binding [GO:1901612]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; lipid transport [GO:0006869]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside metabolic process [GO:0009116]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; lipid transport [GO:0006869]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside metabolic process [GO:0009116]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	ATP binding [GO:0005524]; cardiolipin binding [GO:1901612]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1ehwb__d5yola___1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; cardiolipin binding [GO:1901612]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; lipid transport [GO:0006869]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside metabolic process [GO:0009116]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; lipid transport [GO:0006869]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside metabolic process [GO:0009116]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; cardiolipin binding [GO:1901612]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1ehxa__d1ot1a1__1			Firmicutes	Firmicutes	cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	cellulose binding [GO:0030248]; metal ion binding [GO:0046872]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1ei1b2_d2bt0b___1		Metazoa	Proteobacteria	Chordata	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; DNA-dependent ATPase activity [GO:0008094]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1ei9a__d5tnjc___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; membrane raft [GO:0045121]; nucleus [GO:0005634]; synaptic vesicle [GO:0008021]; palmitoyl-(protein) hydrolase activity [GO:0008474]; palmitoyl-CoA hydrolase activity [GO:0016290]; brain development [GO:0007420]; cofactor metabolic process [GO:0051186]; cofactor transport [GO:0051181]; lipid catabolic process [GO:0016042]; lysosomal lumen acidification [GO:0007042]; membrane raft organization [GO:0031579]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; pinocytosis [GO:0006907]; positive regulation of pinocytosis [GO:0048549]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein depalmitoylation [GO:0002084]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]	hydrolase activity [GO:0016787]	brain development [GO:0007420]; cofactor metabolic process [GO:0051186]; cofactor transport [GO:0051181]; lipid catabolic process [GO:0016042]; lysosomal lumen acidification [GO:0007042]; membrane raft organization [GO:0031579]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; pinocytosis [GO:0006907]; positive regulation of pinocytosis [GO:0048549]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein depalmitoylation [GO:0002084]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]		axon [GO:0030424]; cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; membrane raft [GO:0045121]; nucleus [GO:0005634]; synaptic vesicle [GO:0008021]		palmitoyl-(protein) hydrolase activity [GO:0008474]; palmitoyl-CoA hydrolase activity [GO:0016290]	hydrolase activity [GO:0016787]
d1eiia__d1alba___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	retinol metabolic process [GO:0042572]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	retinal binding [GO:0016918]; retinol binding [GO:0019841]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1eika__d1dzfa2__1		Fungi	Euryarchaeota	Ascomycota	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; transcription, DNA-templated [GO:0006351]	nucleoplasm [GO:0005654]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	transcription, DNA-templated [GO:0006351]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]		nucleoplasm [GO:0005654]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]
d1eila2_d4ghgd2__1			Proteobacteria	Actinobacteria	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]				biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1eima4_d3bzaa1__1				Actinobacteria		dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]						dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1eina__d1qge.1__1	Fungi		Ascomycota	Proteobacteria	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d1eiqa2_d2wl9a1__1			Proteobacteria	Actinobacteria	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	dioxygenase activity [GO:0051213]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]			biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; ferrous iron binding [GO:0008198]
d1eiqa2_d5trxb2__1			Proteobacteria	Actinobacteria	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]				biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1eira2_d3ojtc1__1			Proteobacteria	Actinobacteria	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]				biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1eixb__d3pbya___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; carboxy-lyase activity [GO:0016831]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; nucleobase-containing small molecule interconversion [GO:0015949]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; nucleobase-containing small molecule interconversion [GO:0015949]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		carboxy-lyase activity [GO:0016831]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1eiyb5_d2e3ya1__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]		phenylalanyl-tRNA aminoacylation [GO:0006432]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]	
d1eiyb6_d1ni5a3__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; tRNA(Ile)-lysidine synthase activity [GO:0032267]; tRNA modification [GO:0006400]; tRNA wobble base lysidine biosynthesis [GO:0002136]	phenylalanyl-tRNA aminoacylation [GO:0006432]	tRNA modification [GO:0006400]; tRNA wobble base lysidine biosynthesis [GO:0002136]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; tRNA(Ile)-lysidine synthase activity [GO:0032267]
d1ej0a__d2aowa___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; rRNA (uridine-2'-O-)-methyltransferase activity [GO:0008650]; enzyme-directed rRNA 2'-O-methylation [GO:0000453]; ribosomal large subunit assembly [GO:0000027]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; histamine N-methyltransferase activity [GO:0046539]; brain development [GO:0007420]; histamine catabolic process [GO:0001695]; histidine catabolic process [GO:0006548]; hyperosmotic response [GO:0006972]; methylation [GO:0032259]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to amine [GO:0014075]; response to cocaine [GO:0042220]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to interleukin-1 [GO:0070555]; response to tumor cell [GO:0002347]	enzyme-directed rRNA 2'-O-methylation [GO:0000453]; ribosomal large subunit assembly [GO:0000027]	brain development [GO:0007420]; histamine catabolic process [GO:0001695]; histidine catabolic process [GO:0006548]; hyperosmotic response [GO:0006972]; methylation [GO:0032259]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to amine [GO:0014075]; response to cocaine [GO:0042220]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to interleukin-1 [GO:0070555]; response to tumor cell [GO:0002347]	cytosol [GO:0005829]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]	rRNA (uridine-2'-O-)-methyltransferase activity [GO:0008650]	histamine N-methyltransferase activity [GO:0046539]
d1ej8a__d3km2v___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase copper chaperone activity [GO:0016532]; metal ion transport [GO:0030001]; protein maturation by copper ion transfer [GO:0015680]; removal of superoxide radicals [GO:0019430]	chloroplast [GO:0009507]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	metal ion transport [GO:0030001]; protein maturation by copper ion transfer [GO:0015680]; removal of superoxide radicals [GO:0019430]	removal of superoxide radicals [GO:0019430]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	chloroplast [GO:0009507]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	copper ion binding [GO:0005507]; superoxide dismutase copper chaperone activity [GO:0016532]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]
d1ejaa__d5tkta___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d1ejbb__d1kz4d___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]
d1ejbc__d4gefc___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]		cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]		6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	
d1ejka__d1f0aa___1												
d1ejmc__d1a0jd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]	digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1ejmc__d3qzqd___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cysteine-type endopeptidase activity [GO:0004197]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]
d1ejol1_d3cx5k___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1ejrb__d4z42e___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d1ejub__d1s3tb___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d1ejva__d4furc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d1ek1b2_d5tnpb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]	hydrolase activity [GO:0016787]	cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]		cytosol [GO:0005829]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	hydrolase activity [GO:0016787]
d1ek3a__d3u0pd1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ek3a__d5sv4b1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]	
d1ek4a2_d1ox0a2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d1ek4a2_d4wumb1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	naringenin-chalcone synthase activity [GO:0016210]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	naringenin-chalcone synthase activity [GO:0016210]
d1ek4b1_d2alma2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d1ek4b1_d2byzc2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1ek4b2_d2byyc1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1ek4b2_d4jd3a2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	polyketide synthase complex [GO:0034081]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	polyketide synthase complex [GO:0034081]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1ek4c2_d5wx5e2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1ek4d1_d4xoxb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1ek4d2_d4o9ab2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1ekja__d3e3fb___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast stroma [GO:0009570]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbon utilization [GO:0015976]	carbon utilization [GO:0015976]	chloroplast stroma [GO:0009570]		carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1ekje__d4yf4c1__1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast stroma [GO:0009570]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbon utilization [GO:0015976]		chloroplast stroma [GO:0009570]	plasma membrane [GO:0005886]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1ekjg__d5swcd1__1	Viridiplantae		Streptophyta	Cyanobacteria	chloroplast stroma [GO:0009570]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	cytoplasm [GO:0005737]; carbonate dehydratase activity [GO:0004089]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]; cyanate catabolic process [GO:0009440]	carbon utilization [GO:0015976]	carbon utilization [GO:0015976]; cyanate catabolic process [GO:0009440]	chloroplast stroma [GO:0009570]	cytoplasm [GO:0005737]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d1ekla__d4msia___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]	extracellular region [GO:0005576]			extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1ekma3_d1rkya3__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; amine metabolic process [GO:0009308]; cellular response to inorganic substance [GO:0071241]; oxidation-reduction process [GO:0055114]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; cellular response to inorganic substance [GO:0071241]; oxidation-reduction process [GO:0055114]	peroxisome [GO:0005777]		aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]
d1ekub2_d1itfa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular respiration [GO:1901857]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of iron ion import across plasma membrane [GO:1904440]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vitamin D biosynthetic process [GO:0060557]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein ADP-ribosylation [GO:0010835]; regulation of regulatory T cell differentiation [GO:0045589]; response to virus [GO:0009615]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular respiration [GO:1901857]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of iron ion import across plasma membrane [GO:1904440]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vitamin D biosynthetic process [GO:0060557]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein ADP-ribosylation [GO:0010835]; regulation of regulatory T cell differentiation [GO:0045589]; response to virus [GO:0009615]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]	cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]
d1ekxc2_d3d6nb1__1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	dihydroorotase activity [GO:0004151]; zinc ion binding [GO:0008270]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	dihydroorotase activity [GO:0004151]; zinc ion binding [GO:0008270]
d1el1a1_d1l84a___1	Metazoa		Chordata		lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]; cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]	lysozyme activity [GO:0003796]
d1el1b1_d1g1va___1	Metazoa		Chordata		lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]; cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]	lysozyme activity [GO:0003796]
d1el4a__d5jola___1	Metazoa	Metazoa	Cnidaria	Chordata	calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; podosome [GO:0002102]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; GTPase binding [GO:0051020]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; animal organ regeneration [GO:0031100]; cell migration [GO:0016477]; extracellular matrix disassembly [GO:0022617]; interleukin-12-mediated signaling pathway [GO:0035722]; positive regulation of podosome assembly [GO:0071803]; protein kinase A signaling [GO:0010737]; regulation of intracellular protein transport [GO:0033157]; T cell activation involved in immune response [GO:0002286]	bioluminescence [GO:0008218]	actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; animal organ regeneration [GO:0031100]; cell migration [GO:0016477]; extracellular matrix disassembly [GO:0022617]; interleukin-12-mediated signaling pathway [GO:0035722]; positive regulation of podosome assembly [GO:0071803]; protein kinase A signaling [GO:0010737]; regulation of intracellular protein transport [GO:0033157]; T cell activation involved in immune response [GO:0002286]		actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; podosome [GO:0002102]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	calcium ion binding [GO:0005509]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; GTPase binding [GO:0051020]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]
d1el5b2_d1c0ka2__1		Fungi	Firmicutes	Basidiomycota	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	peroxisome [GO:0005777]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; D-amino acid metabolic process [GO:0046416]	tetrahydrofolate metabolic process [GO:0046653]	D-amino acid metabolic process [GO:0046416]	cytoplasm [GO:0005737]	peroxisome [GO:0005777]	sarcosine oxidase activity [GO:0008115]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]
d1el7a2_d2z3ya3__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	DNA repair complex [GO:1990391]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; androgen receptor binding [GO:0050681]; chromatin binding [GO:0003682]; demethylase activity [GO:0032451]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-dimethyl-K4 specific) [GO:0034648]; histone demethylase activity (H3-K4 specific) [GO:0032453]; histone demethylase activity (H3-K9 specific) [GO:0032454]; MRF binding [GO:0043426]; nuclear receptor transcription coactivator activity [GO:0030374]; oxidoreductase activity [GO:0016491]; p53 binding [GO:0002039]; RNA polymerase II transcription factor binding [GO:0001085]; telomeric DNA binding [GO:0042162]; telomeric repeat-containing RNA binding [GO:0061752]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; alternative mRNA splicing, via spliceosome [GO:0000380]; blood coagulation [GO:0007596]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; histone H3-K9 demethylation [GO:0033169]; muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron maturation [GO:0042551]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of histone ubiquitination [GO:0033184]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of cellular protein localization [GO:1903827]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fungicide [GO:0060992]	tetrahydrofolate metabolic process [GO:0046653]	alternative mRNA splicing, via spliceosome [GO:0000380]; blood coagulation [GO:0007596]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; histone H3-K9 demethylation [GO:0033169]; muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron maturation [GO:0042551]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of histone ubiquitination [GO:0033184]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of cellular protein localization [GO:1903827]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fungicide [GO:0060992]	cytoplasm [GO:0005737]	DNA repair complex [GO:1990391]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]	sarcosine oxidase activity [GO:0008115]	androgen receptor binding [GO:0050681]; chromatin binding [GO:0003682]; demethylase activity [GO:0032451]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-dimethyl-K4 specific) [GO:0034648]; histone demethylase activity (H3-K4 specific) [GO:0032453]; histone demethylase activity (H3-K9 specific) [GO:0032454]; MRF binding [GO:0043426]; nuclear receptor transcription coactivator activity [GO:0030374]; oxidoreductase activity [GO:0016491]; p53 binding [GO:0002039]; RNA polymerase II transcription factor binding [GO:0001085]; telomeric DNA binding [GO:0042162]; telomeric repeat-containing RNA binding [GO:0061752]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1elaa__d3ensb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1elba__d2z9jb___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1elee__d3zvea1__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1elfa__d3qzqa___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	cysteine-type endopeptidase activity [GO:0004197]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]
d1elka__d5ucca___1	Metazoa	Fungi	Chordata	Ascomycota	azurophil granule membrane [GO:0035577]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; clathrin binding [GO:0030276]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; neutrophil degranulation [GO:0043312]; protein transport [GO:0015031]		endocytosis [GO:0006897]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; neutrophil degranulation [GO:0043312]; protein transport [GO:0015031]		azurophil granule membrane [GO:0035577]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]		clathrin binding [GO:0030276]	
d1elkb__d3g2va___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule membrane [GO:0035577]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; clathrin binding [GO:0030276]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; neutrophil degranulation [GO:0043312]; protein transport [GO:0015031]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	endocytosis [GO:0006897]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; neutrophil degranulation [GO:0043312]; protein transport [GO:0015031]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	azurophil granule membrane [GO:0035577]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	clathrin binding [GO:0030276]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]
d1elmp__d1lcpb2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	proteolysis [GO:0006508]		extracellular space [GO:0005615]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]
d1eloa3_d1fwkb1__1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]		threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]
d1eloa4_d3b78c5__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]			cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d1elpa2_d3hzbd___1	Metazoa		Chordata	Bacteroidetes	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1elpb2_d1ziqa2__1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d1elpb2_d5ht9b___1	Metazoa		Chordata	Euryarchaeota	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1elqa__d1wkhb___1			Cyanobacteria	Deinococcus-Thermus	lyase activity [GO:0016829]	cytoplasm [GO:0005737]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]		arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]		cytoplasm [GO:0005737]	lyase activity [GO:0016829]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1elsa1_d3ujfa2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1elxa__d5tpqb1__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1elya__d2anha___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1elyb__d1urab___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1elzb__d1zeda___1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; alkaline phosphatase activity [GO:0004035]; magnesium ion binding [GO:0000287]; zinc ion binding [GO:0008270]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; magnesium ion binding [GO:0000287]; zinc ion binding [GO:0008270]
d1em1a1_d4gunl1__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1emda1_d2ieda___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d1emha__d4wrwa___1	Metazoa		Chordata	Actinobacteria	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d1emha__d5aysa1__1	Metazoa		Chordata	Firmicutes	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	metal ion binding [GO:0046872]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]		mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]	metal ion binding [GO:0046872]
d1emja__d3a7na1__1	Metazoa		Chordata	Actinobacteria	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d1emsb2_d5h8in___1	Metazoa	Viridiplantae	Nematoda (roundworms)	Streptophyta	bis(5'-adenosyl)-triphosphatase activity [GO:0047710]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; nucleotide binding [GO:0000166]; nucleobase-containing compound metabolic process [GO:0006139]	N-carbamoylputrescine amidase activity [GO:0050126]; polyamine biosynthetic process [GO:0006596]	nucleobase-containing compound metabolic process [GO:0006139]	polyamine biosynthetic process [GO:0006596]			bis(5'-adenosyl)-triphosphatase activity [GO:0047710]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; nucleotide binding [GO:0000166]	N-carbamoylputrescine amidase activity [GO:0050126]
d1emth1_d4ened2__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1emtl1_d3jwdd1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1emtl2_d5hysd2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1emua__d1ezya___1	Metazoa	Metazoa	Chordata	Chordata	beta-catenin destruction complex [GO:0030877]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling adaptor activity [GO:0035591]; SMAD binding [GO:0046332]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular protein-containing complex assembly [GO:0034622]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of Wnt signaling pathway [GO:0030111]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; brain development [GO:0007420]; dorsal root ganglion development [GO:1990791]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of dopamine receptor signaling pathway [GO:0060160]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of glycine import across plasma membrane [GO:1900924]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart rate [GO:0010460]; regulation of actin filament organization [GO:0110053]; regulation of calcium ion transport [GO:0051924]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amphetamine [GO:0001975]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to morphine [GO:0043278]	activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular protein-containing complex assembly [GO:0034622]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of Wnt signaling pathway [GO:0030111]; Wnt signaling pathway [GO:0016055]	brain development [GO:0007420]; dorsal root ganglion development [GO:1990791]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of dopamine receptor signaling pathway [GO:0060160]; negative regulation of glycine import across plasma membrane [GO:1900924]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart rate [GO:0010460]; regulation of actin filament organization [GO:0110053]; regulation of calcium ion transport [GO:0051924]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amphetamine [GO:0001975]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to morphine [GO:0043278]	beta-catenin destruction complex [GO:0030877]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; I-SMAD binding [GO:0070411]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling adaptor activity [GO:0035591]; SMAD binding [GO:0046332]; ubiquitin protein ligase binding [GO:0031625]	G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]
d1emya__d4n7oa___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1en4a1_d4gunb1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1en4b1_d1jr9a1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1en4c1_d3tjta1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1en4c2_d1uesc2__1			Proteobacteria	Bacteroidetes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1en4d1_d6elkc1__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	removal of superoxide radicals [GO:0019430]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]
d1en4d2_d3ot7b2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1en5a2_d3c3sa2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1en5b1_d3ak3a1__1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1en5c1_d1xreb1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	removal of superoxide radicals [GO:0019430]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1en5c2_d3dc5a2__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	removal of superoxide radicals [GO:0019430]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]
d1en5d1_d1xuqb1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	removal of superoxide radicals [GO:0019430]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1en6a1_d1ma1c1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1enaa__d5ioda___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1enfa1_d5elcj___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d1enxa1_d5v38b1__1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	negative regulation of neurotransmitter secretion [GO:0046929]	xylan catabolic process [GO:0045493]	negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	
d1enza__d2nu7a1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d1enza__d5icma1__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]
d1eo2a__d3lmxa___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d1eo5a4_d3l4ya2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	carbohydrate metabolic process [GO:0005975]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]
d1eo6a__d3waob___1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; ATPase binding [GO:0051117]; microtubule binding [GO:0008017]; SNARE binding [GO:0000149]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; intra-Golgi vesicle-mediated transport [GO:0006891]; macroautophagy [GO:0016236]; negative regulation of proteasomal protein catabolic process [GO:1901799]; positive regulation of ATPase activity [GO:0032781]; protein transport [GO:0015031]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; intra-Golgi vesicle-mediated transport [GO:0006891]; macroautophagy [GO:0016236]; negative regulation of proteasomal protein catabolic process [GO:1901799]; positive regulation of ATPase activity [GO:0032781]; protein transport [GO:0015031]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	ATPase binding [GO:0051117]; microtubule binding [GO:0008017]; SNARE binding [GO:0000149]; ubiquitin protein ligase binding [GO:0031625]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d1eo6b__d3v6cb1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; ATPase binding [GO:0051117]; microtubule binding [GO:0008017]; SNARE binding [GO:0000149]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; intra-Golgi vesicle-mediated transport [GO:0006891]; macroautophagy [GO:0016236]; negative regulation of proteasomal protein catabolic process [GO:1901799]; positive regulation of ATPase activity [GO:0032781]; protein transport [GO:0015031]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; intra-Golgi vesicle-mediated transport [GO:0006891]; macroautophagy [GO:0016236]; negative regulation of proteasomal protein catabolic process [GO:1901799]; positive regulation of ATPase activity [GO:0032781]; protein transport [GO:0015031]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ATPase binding [GO:0051117]; microtubule binding [GO:0008017]; SNARE binding [GO:0000149]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1eo7a1_d2omva1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	carbohydrate metabolic process [GO:0005975]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1eo7a2_d2j44a2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1eo7a4_d3mv033__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1eo8h1_d3r4dc1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary membrane [GO:0060170]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lateral plasma membrane [GO:0016328]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; actin binding [GO:0003779]; bile acid transmembrane transporter activity [GO:0015125]; calmodulin binding [GO:0005516]; filamin binding [GO:0031005]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; Toll-like receptor binding [GO:0035325]; virus receptor activity [GO:0001618]; bile acid and bile salt transport [GO:0015721]; blood vessel development [GO:0001568]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; common myeloid progenitor cell proliferation [GO:0035726]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; insulin catabolic process [GO:1901143]; insulin receptor internalization [GO:0038016]; negative regulation of bone resorption [GO:0045779]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of vascular permeability [GO:0043116]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of vasculogenesis [GO:2001214]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell growth [GO:0001558]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell migration [GO:0010594]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of homophilic cell adhesion [GO:1903385]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of sprouting angiogenesis [GO:1903670]; wound healing, spreading of cells [GO:0044319]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	bile acid and bile salt transport [GO:0015721]; blood vessel development [GO:0001568]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; common myeloid progenitor cell proliferation [GO:0035726]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; insulin catabolic process [GO:1901143]; insulin receptor internalization [GO:0038016]; negative regulation of bone resorption [GO:0045779]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of vascular permeability [GO:0043116]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of vasculogenesis [GO:2001214]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell growth [GO:0001558]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell migration [GO:0010594]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of homophilic cell adhesion [GO:1903385]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of sprouting angiogenesis [GO:1903670]; wound healing, spreading of cells [GO:0044319]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell surface [GO:0009986]; ciliary membrane [GO:0060170]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lateral plasma membrane [GO:0016328]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	host cell surface receptor binding [GO:0046789]	actin binding [GO:0003779]; bile acid transmembrane transporter activity [GO:0015125]; calmodulin binding [GO:0005516]; filamin binding [GO:0031005]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; Toll-like receptor binding [GO:0035325]; virus receptor activity [GO:0001618]
d1eo8l1_d1rzie2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d1eo8l2_d4lsql2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	structural molecule activity [GO:0005198]
d1eoba__d3hkpa___1			Proteobacteria	Actinobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]; aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]
d1eoga1_d3wd6d2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d1eogb1_d5gzzc2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d1eoha2_d2h76b___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1eohc2_d1xbsa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; cell cycle [GO:0007049]; mRNA splicing, via spliceosome [GO:0000398]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell cycle [GO:0007049]; mRNA splicing, via spliceosome [GO:0000398]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	
d1eohf1_d5echf2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1eohg1_d3zmkd2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	transferase activity [GO:0016740]
d1eohg2_d4edzb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1eohh1_d4e8ed2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	transferase activity [GO:0016740]
d1eohh2_d3q19a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d1eoib__d1idqa___1		Fungi	Proteobacteria	Ascomycota	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]	extracellular region [GO:0005576]; chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]			outer membrane-bounded periplasmic space [GO:0030288]	extracellular region [GO:0005576]	acid phosphatase activity [GO:0003993]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]
d1eooa__d4e5fc___1			Proteobacteria	Negarnaviricota	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cap snatching [GO:0075526]; suppression by virus of host RNA polymerase II activity [GO:0039523]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	DNA restriction-modification system [GO:0009307]	cap snatching [GO:0075526]; suppression by virus of host RNA polymerase II activity [GO:0039523]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]		host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d1eoqa__d4wyme2__1					host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]; aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral procapsid maturation [GO:0046797]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral procapsid maturation [GO:0046797]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1eoua__d3u3ax___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1ep2b1_d3w5uc1__1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; 'de novo' UMP biosynthetic process [GO:0044205]	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	'de novo' UMP biosynthetic process [GO:0044205]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	cytoplasm [GO:0005737]	chloroplast thylakoid membrane protein complex [GO:0098807]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d1ep2b2_d2x3ua2__1			Firmicutes	Cyanobacteria	cytoplasm [GO:0005737]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; 'de novo' UMP biosynthetic process [GO:0044205]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	'de novo' UMP biosynthetic process [GO:0044205]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d1ep2b2_d5ue9d2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]	dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]
d1ep3b1_d2bgjc1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1ep5b__d5etxb1__1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; transformation of host cell by virus [GO:0019087]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]	transformation of host cell by virus [GO:0019087]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d1ep5c__d2bm2c___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]	proteolysis [GO:0006508]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1ep5c__d3su6a1__1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ep6a__d2lpra___1				Proteobacteria	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]		host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	serine-type endopeptidase activity [GO:0004252]
d1ep6c__d4mpxa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1ep8a__d4hqzb___1	Viridiplantae		Chlorophyta	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	protein disulfide oxidoreductase activity [GO:0015035]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]
d1ep8b__d4j56f1__1	Viridiplantae		Chlorophyta	Apicomplexa	cell [GO:0005623]; cytoplasm [GO:0005737]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]	protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d1epba__d1ywca___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular region [GO:0005576]; small molecule binding [GO:0036094]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]		vasodilation [GO:0042311]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	small molecule binding [GO:0036094]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d1epba__d5l8ia___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; lipid binding [GO:0008289]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; negative regulation of cell population proliferation [GO:0008285]; triglyceride catabolic process [GO:0019433]		lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; negative regulation of cell population proliferation [GO:0008285]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	small molecule binding [GO:0036094]	lipid binding [GO:0008289]
d1epfb1_d2iana1__1	Metazoa	Metazoa	Chordata	Chordata	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1epfb1_d5bw7c2__1	Metazoa	Metazoa	Chordata	Chordata	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]	IgG binding [GO:0019864]
d1epfb2_d1i8ld___1	Metazoa	Metazoa	Chordata	Chordata	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]	cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]	
d1epfc2_d4h88l1__1	Metazoa	Metazoa	Chordata	Chordata	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	anchored component of membrane [GO:0031225]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of catalytic activity [GO:0043086]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization [GO:0032880]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of catalytic activity [GO:0043086]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization [GO:0032880]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to oxidative stress [GO:0006979]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	anchored component of membrane [GO:0031225]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d1eple__d4djrb___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]
d1epne__d2aoia___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1epoe__d3pwrb___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1epqe__d3d1zb___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1epwa2_d4h9wa___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	serine-type endopeptidase inhibitor activity [GO:0004867]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]		lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1epxd__d3pfpa1__1				Actinobacteria	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; manganese ion binding [GO:0030145]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; protein homooligomerization [GO:0051260]	glycolytic process [GO:0006096]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; protein homooligomerization [GO:0051260]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	fructose-bisphosphate aldolase activity [GO:0004332]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; manganese ion binding [GO:0030145]
d1epza__d1pm7b___1			Euryarchaeota	Actinobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]			dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d1epza__d1qxra___1			Euryarchaeota	Euryarchaeota	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]
d1eq6a__d1jhsa___1	Fungi	Fungi	Ascomycota	Ascomycota	nucleus [GO:0005634]; Ran GTPase binding [GO:0008536]; mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606]	nucleus [GO:0005634]; Ran GTPase binding [GO:0008536]; mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606]	mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606]	mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606]	nucleus [GO:0005634]	nucleus [GO:0005634]	Ran GTPase binding [GO:0008536]	Ran GTPase binding [GO:0008536]
d1eq9b__d5c3na___1	Metazoa		Arthropoda		extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]
d1eqba__d2f8jd___1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; membrane [GO:0016020]; amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]; cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	histidine biosynthetic process [GO:0000105]	cytosol [GO:0005829]; membrane [GO:0016020]		amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]
d1eqbb__d1s07b___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]; cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	biotin biosynthetic process [GO:0009102]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]
d1eqbd__d1ohwc___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]; cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	cellular response to tetrahydrofolate [GO:1904482]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine catabolic process [GO:0006546]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	cytosol [GO:0005829]; membrane [GO:0016020]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]	(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]
d1eqca__d1fp9a___1	Fungi		Ascomycota	Deinococcus-Thermus	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]; cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]		cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]	cytoplasm [GO:0005737]	cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]
d1eqda__d4i3bf___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cytoplasm [GO:0005737]; lipid binding [GO:0008289]; bioluminescence [GO:0008218]	vasodilation [GO:0042311]	bioluminescence [GO:0008218]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	lipid binding [GO:0008289]
d1eqfa1_d5nrwa___1	Metazoa	Metazoa	Chordata	Chordata	MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]; ATP binding [GO:0005524]; histone acetyltransferase activity [GO:0004402]; kinase activity [GO:0016301]; lysine-acetylated histone binding [GO:0070577]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein heterodimerization activity [GO:0046982]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin conjugating enzyme activity [GO:0061631]; cell cycle [GO:0007049]; cellular response to ATP [GO:0071318]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA-templated transcription, initiation [GO:0006352]; midbrain development [GO:0030901]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of protein autoubiquitination [GO:1905524]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010768]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription initiation from RNA polymerase II promoter [GO:0060260]; regulation of transcription, DNA-templated [GO:0006355]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription factor catabolic process [GO:0036369]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cell cycle [GO:0007049]; cellular response to ATP [GO:0071318]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA-templated transcription, initiation [GO:0006352]; midbrain development [GO:0030901]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of protein autoubiquitination [GO:1905524]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010768]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription initiation from RNA polymerase II promoter [GO:0060260]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription factor catabolic process [GO:0036369]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; histone acetyltransferase activity [GO:0004402]; kinase activity [GO:0016301]; lysine-acetylated histone binding [GO:0070577]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein heterodimerization activity [GO:0046982]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin conjugating enzyme activity [GO:0061631]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1eqha1_d2euqa2__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1eqka__d2w9pf___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; defense response [GO:0006952]	cysteine-type endopeptidase inhibitor activity [GO:0004869]	defense response [GO:0006952]		extracellular region [GO:0005576]		cysteine-type endopeptidase inhibitor activity [GO:0004869]	cysteine-type endopeptidase inhibitor activity [GO:0004869]
d1eqqa__d1jb7a1__1			Proteobacteria	Ciliophora	cytosol [GO:0005829]; enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]	telomere capping [GO:0016233]	cytosol [GO:0005829]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1eqqd__d1pv4f2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]	DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]	enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]
d1eqra1_d1eova1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	aspartyl-tRNA aminoacylation [GO:0006422]	aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]
d1eqra1_d2ix1a1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]; 3'-5' exonuclease activity [GO:0008408]; exoribonuclease II activity [GO:0008859]; RNA binding [GO:0003723]; mRNA catabolic process [GO:0006402]	aspartyl-tRNA aminoacylation [GO:0006422]	mRNA catabolic process [GO:0006402]	cytosol [GO:0005829]	cytosol [GO:0005829]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]	3'-5' exonuclease activity [GO:0008408]; exoribonuclease II activity [GO:0008859]; RNA binding [GO:0003723]
d1eqra2_d1l0wb2__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	aspartyl-tRNA aminoacylation [GO:0006422]	aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]
d1eqrc2_d2d6fc2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]; translation [GO:0006412]	aspartyl-tRNA aminoacylation [GO:0006422]	translation [GO:0006412]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]
d1eqwd__d2gbtb___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	removal of superoxide radicals [GO:0019430]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	periplasmic space [GO:0042597]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; superoxide dismutase activity [GO:0004784]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1eqys__d4pkhj___1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d1eqza__d5jrgd___1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleosome [GO:0000786]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1erba__d2eu7x___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular space [GO:0005615]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]		vasodilation [GO:0042311]	extracellular space [GO:0005615]	extracellular region [GO:0005576]	retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]
d1erta__d1aaza___1	Metazoa		Chordata		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d1erwa__d1m2db___1	Metazoa		Chordata	Aquificae	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]
d1erza__d2fkud___1			Proteobacteria		N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]	
d1es0b2_d3sdda1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1esba__d2d1ja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1esea__d3w7va___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; carboxylic ester hydrolase activity [GO:0052689]	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	carboxylic ester hydrolase activity [GO:0052689]	acetylxylan esterase activity [GO:0046555]
d1esgb__d3v21a___1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	endonuclease activity [GO:0004519]	DNA restriction-modification system [GO:0009307]				DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]	endonuclease activity [GO:0004519]
d1esja1_d5kb6a___1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; hydroxyethylthiazole kinase activity [GO:0004417]; magnesium ion binding [GO:0000287]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; adenosine metabolic process [GO:0046085]; AMP salvage [GO:0044209]; dATP biosynthetic process [GO:0006175]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of T cell proliferation [GO:0042102]; purine ribonucleoside salvage [GO:0006166]; type B pancreatic cell proliferation [GO:0044342]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	adenosine metabolic process [GO:0046085]; AMP salvage [GO:0044209]; dATP biosynthetic process [GO:0006175]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of T cell proliferation [GO:0042102]; purine ribonucleoside salvage [GO:0006166]; type B pancreatic cell proliferation [GO:0044342]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; hydroxyethylthiazole kinase activity [GO:0004417]; magnesium ion binding [GO:0000287]	adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d1esla1_d3wwkc___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; clathrin-coated pit [GO:0005905]; cortical cytoskeleton [GO:0030863]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; oligosaccharide binding [GO:0070492]; phospholipase binding [GO:0043274]; sialic acid binding [GO:0033691]; transmembrane signaling receptor activity [GO:0004888]; actin filament-based process [GO:0030029]; activation of phospholipase C activity [GO:0007202]; calcium-mediated signaling [GO:0019722]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte migration involved in inflammatory response [GO:0002523]; leukocyte tethering or rolling [GO:0050901]; positive regulation of receptor internalization [GO:0002092]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	actin filament-based process [GO:0030029]; activation of phospholipase C activity [GO:0007202]; calcium-mediated signaling [GO:0019722]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte migration involved in inflammatory response [GO:0002523]; leukocyte tethering or rolling [GO:0050901]; positive regulation of receptor internalization [GO:0002092]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]	regulation of cytokine activity [GO:0060300]	caveola [GO:0005901]; clathrin-coated pit [GO:0005905]; cortical cytoskeleton [GO:0030863]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; oligosaccharide binding [GO:0070492]; phospholipase binding [GO:0043274]; sialic acid binding [GO:0033691]; transmembrane signaling receptor activity [GO:0004888]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1espa__d3ehya___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1esta__d1bth.2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d1esva2_d2zf5o1__1	Metazoa		Chordata	Euryarchaeota	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cytosol [GO:0005829]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d1eswa__d3lxba1__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cytoplasm [GO:0005737]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d1esza__d1toaa___1			Proteobacteria	Spirochaetes	outer membrane-bounded periplasmic space [GO:0030288]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; zinc ion transport [GO:0006829]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	cell adhesion [GO:0007155]; zinc ion transport [GO:0006829]	outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]		metal ion binding [GO:0046872]
d1et5a2_d1l9qb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1et5a2_d4azud___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1et6a1_d1qilc1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]	toxin activity [GO:0090729]
d1et7a2_d1pzca___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1et9a2_d1se2a2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1etb1__d2g2pa___1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	periplasmic space [GO:0042597]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]
d1etec__d3dgcm___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; membrane [GO:0016020]; cytokine activity [GO:0005125]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; cytokine-mediated signaling pathway [GO:0019221]; embryonic hemopoiesis [GO:0035162]; homeostasis of number of cells within a tissue [GO:0048873]; lymphocyte differentiation [GO:0030098]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process in bone marrow cell [GO:0071866]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of osteoclast proliferation [GO:0090290]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of myeloid dendritic cell activation [GO:0030885]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]; acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	cytokine-mediated signaling pathway [GO:0019221]; embryonic hemopoiesis [GO:0035162]; homeostasis of number of cells within a tissue [GO:0048873]; lymphocyte differentiation [GO:0030098]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process in bone marrow cell [GO:0071866]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of osteoclast proliferation [GO:0090290]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of myeloid dendritic cell activation [GO:0030885]; signal transduction [GO:0007165]	acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; membrane [GO:0016020]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]	cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]
d1ethc2_d3fvti___1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; enzyme activator activity [GO:0008047]; digestion [GO:0007586]; lipid catabolic process [GO:0016042]; response to bacterium [GO:0009617]; response to food [GO:0032094]	acetylesterase activity [GO:0008126]	digestion [GO:0007586]; lipid catabolic process [GO:0016042]; response to bacterium [GO:0009617]; response to food [GO:0032094]		extracellular region [GO:0005576]		enzyme activator activity [GO:0008047]	acetylesterase activity [GO:0008126]
d1etja__d1aozb1__1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]
d1etjb__d4mfhb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1etjb__d5i6ka1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1etjd__d4yscc1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1etpb1_d1m6zc2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1ett.1_d1p06a___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1ett.1_d2g5va___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1etza2_d4y5yb___1	Metazoa	Metazoa	Chordata	Chordata		extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]		brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]		extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]		erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]
d1etzb1_d5k9ql1__1	Metazoa		Chordata	Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d1etzb2_d1s5ha1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1etzl2_d2xy1a2__1	Metazoa	Metazoa	Chordata	Chordata		axon [GO:0030424]; integral component of membrane [GO:0016021]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; axonal fasciculation [GO:0007413]; neuron cell-cell adhesion [GO:0007158]; sensory perception of smell [GO:0007608]		axonal fasciculation [GO:0007413]; neuron cell-cell adhesion [GO:0007158]; sensory perception of smell [GO:0007608]		axon [GO:0030424]; integral component of membrane [GO:0016021]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]
d1eu4a1_d1hxyd1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	extracellular region [GO:0005576]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	toxin activity [GO:0090729]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1eu5a1_d2qlpa___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d1eu8a__d1dppc___1			Euryarchaeota	Proteobacteria	plasma membrane [GO:0005886]; carbohydrate transport [GO:0008643]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; dipeptide transmembrane transporter activity [GO:0071916]; heme binding [GO:0020037]; peptide binding [GO:0042277]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; chemotaxis [GO:0006935]; dipeptide transport [GO:0042938]; protein transport [GO:0015031]	carbohydrate transport [GO:0008643]	chaperone-mediated protein folding [GO:0061077]; chemotaxis [GO:0006935]; dipeptide transport [GO:0042938]; protein transport [GO:0015031]	plasma membrane [GO:0005886]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]		dipeptide transmembrane transporter activity [GO:0071916]; heme binding [GO:0020037]; peptide binding [GO:0042277]; peptide transmembrane transporter activity [GO:1904680]
d1euba__d3fcqa___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1euda1_d1cqia1__1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d1eufa__d3d23c___1	Metazoa		Chordata		serine-type endopeptidase activity [GO:0004252]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1eufa__d5mnba___1	Metazoa	Metazoa	Chordata	Chordata	serine-type endopeptidase activity [GO:0004252]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1euia__d4zbxa___1			Proteobacteria	Crenarchaeota	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; uracil DNA N-glycosylase activity [GO:0004844]; DNA repair [GO:0006281]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	DNA repair [GO:0006281]	mitochondrion [GO:0005739]; nucleus [GO:0005634]		uracil DNA N-glycosylase activity [GO:0004844]	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; uracil DNA N-glycosylase activity [GO:0004844]
d1euja__d1jjcb3__1	Metazoa		Chordata	Deinococcus-Thermus	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; cytokine activity [GO:0005125]; GTPase binding [GO:0051020]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; chemotaxis [GO:0006935]; defense response to virus [GO:0051607]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of glucagon secretion [GO:0070094]; response to wounding [GO:0009611]; signal transduction [GO:0007165]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; chemotaxis [GO:0006935]; defense response to virus [GO:0051607]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of glucagon secretion [GO:0070094]; response to wounding [GO:0009611]; signal transduction [GO:0007165]; tRNA aminoacylation for protein translation [GO:0006418]	phenylalanyl-tRNA aminoacylation [GO:0006432]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	cytokine activity [GO:0005125]; GTPase binding [GO:0051020]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]
d1eujb__d1vs7q1__1	Metazoa		Chordata		aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; cytokine activity [GO:0005125]; GTPase binding [GO:0051020]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; chemotaxis [GO:0006935]; defense response to virus [GO:0051607]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of glucagon secretion [GO:0070094]; response to wounding [GO:0009611]; signal transduction [GO:0007165]; tRNA aminoacylation for protein translation [GO:0006418]		angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; chemotaxis [GO:0006935]; defense response to virus [GO:0051607]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of glucagon secretion [GO:0070094]; response to wounding [GO:0009611]; signal transduction [GO:0007165]; tRNA aminoacylation for protein translation [GO:0006418]		aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]		cytokine activity [GO:0005125]; GTPase binding [GO:0051020]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]	
d1euma__d2x175___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]
d1eumc__d2c41d___1			Proteobacteria	Cyanobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1eumf__d3dhzb___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1eunb__d5dbth___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	metabolic process [GO:0008152]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]	deoxyribose-phosphate aldolase activity [GO:0004139]
d1euoa1_d1kqwa___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	lipid binding [GO:0008289]	vasodilation [GO:0042311]		extracellular region [GO:0005576]		histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	lipid binding [GO:0008289]
d1eupa__d4c9lb___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; erythromycin biosynthetic process [GO:1901115]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	erythromycin biosynthetic process [GO:1901115]; oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1eura__d3cl2g___1			Actinobacteria	Negarnaviricota	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	extracellular region [GO:0005576]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1euta2_d4yw6b___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	metabolic process [GO:0008152]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	carbohydrate binding [GO:0030246]
d1euta3_d4b7mb___1			Actinobacteria	Negarnaviricota	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	extracellular region [GO:0005576]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1euua1_d5b1cb___1			Actinobacteria		extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	metabolic process [GO:0008152]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1euua3_d3nssa___1			Actinobacteria	Negarnaviricota	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	extracellular region [GO:0005576]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1euvb__d4kslh1__1	Fungi	Metazoa	Ascomycota	Chordata	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]; identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	protein sumoylation [GO:0016925]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1euza1_d1v9lf1__1			Euryarchaeota	Crenarchaeota	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]			glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1euza2_d3tozd1__1			Euryarchaeota	Firmicutes	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1euzc2_d2yfqa1__1			Euryarchaeota	Firmicutes	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]			glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	glutamate dehydrogenase (NAD+) activity [GO:0004352]
d1euzd1_d1yxma1__1		Metazoa	Euryarchaeota	Chordata	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; signaling receptor binding [GO:0005102]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid alpha-oxidation [GO:0001561]; fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114]; phytol metabolic process [GO:0033306]; protein targeting to peroxisome [GO:0006625]	cellular amino acid metabolic process [GO:0006520]	fatty acid alpha-oxidation [GO:0001561]; fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114]; phytol metabolic process [GO:0033306]; protein targeting to peroxisome [GO:0006625]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	signaling receptor binding [GO:0005102]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]
d1euzd2_d1l1fb2__1		Metazoa	Euryarchaeota	Chordata	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]
d1euze2_d4fcck1__1			Euryarchaeota	Proteobacteria	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]			glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1ev11__d1rue3___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ev2b__d41bia___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d1ev2d__d2hw9b1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1ev2f1_d4nyld1__1	Metazoa		Chordata		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]		angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	
d1ev2g1_d1xf3l1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ev2h1_d1d9kf___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	T cell receptor complex [GO:0042101]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	
d1ev4a1_d5n9ua2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]; aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; protein glutathionylation [GO:0010731]	aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	protein glutathionylation [GO:0010731]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]		drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]
d1ev4c2_d1tkdb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]; aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1ev9a2_d1j08f1__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]; aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]	cell [GO:0005623]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d1ev9c1_d5ecqc2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]; aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1ev9c2_d1aqxc2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]; aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1evea__d3aimb___1	Metazoa		Chordata	Crenarchaeota	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]		acetylcholinesterase activity [GO:0003990]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]
d1evha__d2d2qa2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell junction [GO:0030054]; cytosol [GO:0005829]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; synapse [GO:0045202]; actin binding [GO:0003779]; profilin binding [GO:0005522]; SH3 domain binding [GO:0017124]; WW domain binding [GO:0050699]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin polymerization or depolymerization [GO:0008154]; actin polymerization-dependent cell motility [GO:0070358]; axon guidance [GO:0007411]; cellular response to leukemia inhibitory factor [GO:1990830]; neural tube closure [GO:0001843]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin polymerization-dependent cell motility [GO:0070358]; actin polymerization or depolymerization [GO:0008154]; axon guidance [GO:0007411]; cellular response to leukemia inhibitory factor [GO:1990830]; neural tube closure [GO:0001843]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin cytoskeleton [GO:0015629]; cell junction [GO:0030054]; cytosol [GO:0005829]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; synapse [GO:0045202]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	actin binding [GO:0003779]; profilin binding [GO:0005522]; SH3 domain binding [GO:0017124]; WW domain binding [GO:0050699]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d1evia2_d1ryid2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]; cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	cytoplasm [GO:0005737]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]
d1evia2_d4uxna3__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1evib2_d2gmhb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of mitochondrial inner membrane [GO:0031305]; membrane [GO:0016020]; mitochondrion [GO:0005739]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; electron-transferring-flavoprotein dehydrogenase activity [GO:0004174]; flavin adenine dinucleotide binding [GO:0050660]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, oxidizing metal ions with flavin as acceptor [GO:0043783]; ubiquinone binding [GO:0048039]; electron transport chain [GO:0022900]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	electron transport chain [GO:0022900]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	integral component of mitochondrial inner membrane [GO:0031305]; membrane [GO:0016020]; mitochondrion [GO:0005739]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; electron-transferring-flavoprotein dehydrogenase activity [GO:0004174]; flavin adenine dinucleotide binding [GO:0050660]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, oxidizing metal ions with flavin as acceptor [GO:0043783]; ubiquinone binding [GO:0048039]
d1evka1_d1kmma1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytosol [GO:0005829]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	histidyl-tRNA aminoacylation [GO:0006427]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]
d1evkb1_d2g4cc1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1evkb1_d3uh0a2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; mitochondrial threonyl-tRNA aminoacylation [GO:0070159]; threonyl-tRNA aminoacylation [GO:0006435]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	mitochondrial threonyl-tRNA aminoacylation [GO:0070159]; threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]
d1evkb2_d1h4sa2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	prolyl-tRNA aminoacylation [GO:0006433]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]
d1evlb1_d1qe0a1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	histidyl-tRNA aminoacylation [GO:0006427]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]
d1evlc2_d1yfsa2__1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytosol [GO:0005829]; alanine-tRNA ligase activity [GO:0004813]; amino acid binding [GO:0016597]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; alanyl-tRNA aminoacylation [GO:0006419]; tRNA modification [GO:0006400]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	alanyl-tRNA aminoacylation [GO:0006419]; tRNA modification [GO:0006400]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	alanine-tRNA ligase activity [GO:0004813]; amino acid binding [GO:0016597]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1evld2_d2e41a2__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d1evtb__d3homa1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1evtb__d4r6ud___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d1evtc1_d5laxb2__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d1evtd1_d3ch1g2__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1evub3_d1evua2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1evwd__d2o6mb___1					endonuclease activity [GO:0004519]; intron homing [GO:0006314]	endonuclease activity [GO:0004519]; intron homing [GO:0006314]	intron homing [GO:0006314]	intron homing [GO:0006314]			endonuclease activity [GO:0004519]	endonuclease activity [GO:0004519]
d1evxa__d1u3em1__1					endonuclease activity [GO:0004519]; intron homing [GO:0006314]	endonuclease activity [GO:0004519]; intron homing [GO:0006314]	intron homing [GO:0006314]	intron homing [GO:0006314]			endonuclease activity [GO:0004519]	endonuclease activity [GO:0004519]
d1evya2_d1pgqa2__1		Metazoa		Chordata	glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycosome [GO:0020015]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]	cytoplasm [GO:0005737]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]	D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycosome [GO:0020015]	cytoplasm [GO:0005737]	glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]
d1evza2_d4ei2b1__1				Euryarchaeota	glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycosome [GO:0020015]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]	potassium ion transport [GO:0006813]	glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycosome [GO:0020015]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1ew0a__d3t50b___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; nitrogen fixation [GO:0009399]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; photoreceptor activity [GO:0009881]; protein histidine kinase activity [GO:0004673]; pathogenesis [GO:0009405]; protein-chromophore linkage [GO:0018298]; response to stimulus [GO:0050896]	nitrogen fixation [GO:0009399]; regulation of transcription, DNA-templated [GO:0006355]	pathogenesis [GO:0009405]; protein-chromophore linkage [GO:0018298]; response to stimulus [GO:0050896]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]	ATP binding [GO:0005524]; photoreceptor activity [GO:0009881]; protein histidine kinase activity [GO:0004673]
d1ew4a__d3oeqa___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; iron-sulfur cluster assembly [GO:0016226]	cell [GO:0005623]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron chaperone activity [GO:0034986]; cellular iron ion homeostasis [GO:0006879]; glutathione metabolic process [GO:0006749]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; mitochondrion organization [GO:0007005]; response to iron(II) ion [GO:0010040]; response to oxidative stress [GO:0006979]	iron-sulfur cluster assembly [GO:0016226]	cellular iron ion homeostasis [GO:0006879]; glutathione metabolic process [GO:0006749]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; mitochondrion organization [GO:0007005]; response to iron(II) ion [GO:0010040]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron chaperone activity [GO:0034986]
d1ew6a__d5hy8t___1	Metazoa	Metazoa	Annelida	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ew8a__d4km4a___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1ewca1_d1ha5b1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ewda__d3s42a1__1	Metazoa		Chordata	Proteobacteria	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	I band [GO:0031674]; M band [GO:0031430]		fructose-bisphosphate aldolase activity [GO:0004332]	3-dehydroquinate dehydratase activity [GO:0003855]
d1ewgc__d2nuwa___1				Crenarchaeota		2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]
d1ewhb2_d1ctma2__1	Viridiplantae	Viridiplantae	Chlorophyta	Streptophyta	chloroplast [GO:0009507]; chloroplast thylakoid membrane [GO:0009535]; integral component of thylakoid membrane [GO:0031361]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	chloroplast thylakoid membrane [GO:0009535]; integral component of thylakoid membrane [GO:0031361]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	photosynthesis [GO:0015979]	photosynthesis [GO:0015979]	chloroplast [GO:0009507]; chloroplast thylakoid membrane [GO:0009535]; integral component of thylakoid membrane [GO:0031361]	chloroplast thylakoid membrane [GO:0009535]; integral component of thylakoid membrane [GO:0031361]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1ewje__d2p7mf___1			Proteobacteria	Firmicutes	drug binding [GO:0008144]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]	drug binding [GO:0008144]	metal ion binding [GO:0046872]
d1ewjf__d1lqpa___1			Proteobacteria	Proteobacteria	drug binding [GO:0008144]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; metal ion binding [GO:0046872]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]	drug binding [GO:0008144]	glutathione transferase activity [GO:0004364]; metal ion binding [GO:0046872]
d1ewxa__d13gsa2__1		Metazoa		Chordata	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1ewya1_d4k1xa1__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1ewyb2_d1sm4b2__1		Viridiplantae	Cyanobacteria	Streptophyta	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]	chloroplast [GO:0009507]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1ewyc__d2wu5b1__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	oxidation-reduction process [GO:0055114]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	phycobilisome [GO:0030089]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d1ex0a3_d1nuga2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]
d1ex0a4_d1evua4__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1ex0b2_d3ly6c3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1ex0b3_d1kv3a2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1ex1a1_d1smda2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d1ex2b__d2j4eb___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide metabolic process [GO:0009117]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; dITP diphosphatase activity [GO:0035870]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; chromosome organization [GO:0051276]; deoxyribonucleoside triphosphate catabolic process [GO:0009204]; ITP catabolic process [GO:0006193]; nucleoside triphosphate catabolic process [GO:0009143]; purine nucleotide catabolic process [GO:0006195]	nucleotide metabolic process [GO:0009117]	chromosome organization [GO:0051276]; deoxyribonucleoside triphosphate catabolic process [GO:0009204]; ITP catabolic process [GO:0006193]; nucleoside triphosphate catabolic process [GO:0009143]; purine nucleotide catabolic process [GO:0006195]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]	NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]	dITP diphosphatase activity [GO:0035870]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]
d1ex5d__d3cwnb___1	Metazoa		Chordata	Proteobacteria	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	I band [GO:0031674]; M band [GO:0031430]	cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d1ex9a__d4uhfa1__1			Proteobacteria	Planctomycetes	extracellular region [GO:0005576]; lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]; protein secretion by the type II secretion system [GO:0015628]; protein transport by the Sec complex [GO:0043952]	metal ion binding [GO:0046872]; methyl indole-3-acetate esterase activity [GO:0080030]	lipid catabolic process [GO:0016042]; protein secretion by the type II secretion system [GO:0015628]; protein transport by the Sec complex [GO:0043952]		extracellular region [GO:0005576]		lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; methyl indole-3-acetate esterase activity [GO:0080030]
d1exca__d2dvna___1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide metabolic process [GO:0009117]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleotide metabolic process [GO:0009117]	nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	cytoplasm [GO:0005737]		NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]
d1excb__d2i5da2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide metabolic process [GO:0009117]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; dITP diphosphatase activity [GO:0035870]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; chromosome organization [GO:0051276]; deoxyribonucleoside triphosphate catabolic process [GO:0009204]; ITP catabolic process [GO:0006193]; nucleoside triphosphate catabolic process [GO:0009143]; purine nucleotide catabolic process [GO:0006195]	nucleotide metabolic process [GO:0009117]	chromosome organization [GO:0051276]; deoxyribonucleoside triphosphate catabolic process [GO:0009204]; ITP catabolic process [GO:0006193]; nucleoside triphosphate catabolic process [GO:0009143]; purine nucleotide catabolic process [GO:0006195]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]	NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]	dITP diphosphatase activity [GO:0035870]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]
d1exda2_d3kt8c___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	tryptophanyl-tRNA aminoacylation [GO:0006436]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d1exea__d1p71a___1				Cyanobacteria	DNA binding [GO:0003677]	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]		chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1exea__d4pt4a___1				Actinobacteria	DNA binding [GO:0003677]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; double-stranded DNA binding [GO:0003690]; supercoiled DNA binding [GO:0097100]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; cellular response to iron ion starvation [GO:0010106]; chromosome condensation [GO:0030261]; DNA protection [GO:0042262]; nucleoid organization [GO:0090143]; positive regulation of transcription, DNA-templated [GO:0045893]		cellular response to iron ion starvation [GO:0010106]; chromosome condensation [GO:0030261]; DNA protection [GO:0042262]; nucleoid organization [GO:0090143]; positive regulation of transcription, DNA-templated [GO:0045893]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; double-stranded DNA binding [GO:0003690]; supercoiled DNA binding [GO:0097100]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1exha__d2xbda___1			Actinobacteria	Actinobacteria	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]	endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]
d1exha__d5m0ya1__1			Actinobacteria	Firmicutes	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1exma2_d4j0qe3__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1exra__d1cmga___1		Metazoa	Ciliophora	Chordata	calcium ion binding [GO:0005509]; calcium-mediated signaling [GO:0019722]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]; calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]; calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	calcium-mediated signaling [GO:0019722]	calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]
d1exua1_d1d9kc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1exub__d4zfgl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]
d1exzb__d1rmia___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; stem cell factor receptor binding [GO:0005173]; cell adhesion [GO:0007155]; ectopic germ cell programmed cell death [GO:0035234]; embryonic hemopoiesis [GO:0035162]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; male gonad development [GO:0008584]; MAPK cascade [GO:0000165]; negative regulation of mast cell apoptotic process [GO:0033026]; neural crest cell migration [GO:0001755]; ovarian follicle development [GO:0001541]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell proliferation [GO:0070668]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of myeloid leukocyte differentiation [GO:0002763]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]		cell adhesion [GO:0007155]; ectopic germ cell programmed cell death [GO:0035234]; embryonic hemopoiesis [GO:0035162]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; male gonad development [GO:0008584]; MAPK cascade [GO:0000165]; negative regulation of mast cell apoptotic process [GO:0033026]; neural crest cell migration [GO:0001755]; ovarian follicle development [GO:0001541]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell proliferation [GO:0070668]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of myeloid leukocyte differentiation [GO:0002763]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]		cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]		cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; stem cell factor receptor binding [GO:0005173]	
d1ey3d__d1o8uf___1	Metazoa		Chordata	Actinobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	fatty acid beta-oxidation [GO:0006635]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]
d1ey3f__d4q1jb___1	Metazoa		Chordata	Firmicutes	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	cytoplasm [GO:0005737]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; antibiotic biosynthetic process [GO:0017000]; fatty acid beta-oxidation [GO:0006635]	fatty acid beta-oxidation [GO:0006635]	antibiotic biosynthetic process [GO:0017000]; fatty acid beta-oxidation [GO:0006635]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]
d1eymb__d4drkb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1eysc__d7prcc___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane light-harvesting complex [GO:0030077]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; photosynthesis, light reaction [GO:0019684]	plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	photosynthesis, light reaction [GO:0019684]	photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	integral component of membrane [GO:0016021]; plasma membrane light-harvesting complex [GO:0030077]	plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1eyvb__d1tzxb___1			Actinobacteria	Thermotogae	cytosol [GO:0005829]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]	cytosol [GO:0005829]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]	DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]	DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]	cytosol [GO:0005829]	cytosol [GO:0005829]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d1eyxa__d2vjha___1			Rhodophyta	Cyanobacteria	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	phycobilisome [GO:0030089]		
d1eyyb__d4i1wb___1			Proteobacteria	Proteobacteria	aldehyde dehydrogenase (NADP+) activity [GO:0033721]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]					aldehyde dehydrogenase (NADP+) activity [GO:0033721]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1eyyc__d4e3xb1__1		Metazoa	Proteobacteria	Chordata	aldehyde dehydrogenase (NADP+) activity [GO:0033721]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; identical protein binding [GO:0042802]; proline catabolic process to glutamate [GO:0010133]		proline catabolic process to glutamate [GO:0010133]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	aldehyde dehydrogenase (NADP+) activity [GO:0033721]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; identical protein binding [GO:0042802]
d1eyza1_d3lp8a3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytosol [GO:0005829]		acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d1ez1a2_d4mv9a1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytosol [GO:0005829]		acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1ez1b2_d4zqia1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]	cytosol [GO:0005829]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1ez4b1_d4nd1b1__1			Firmicutes	Apicomplexa	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d1ez4b2_d4qsme2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-lactate dehydrogenase activity [GO:0004459]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1ez8a__d4eqna___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1ezka1_d1n8jk___1				Proteobacteria	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]		thioredoxin peroxidase activity [GO:0008379]
d1ezlc__d3asnb2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	oxidation-reduction process [GO:0055114]	ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1ezld__d4bwtb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1ezma__d1sqma3__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; bacterial-type flagellum-dependent swarming motility [GO:0071978]; pathogenesis [GO:0009405]; protein secretion by the type II secretion system [GO:0015628]; protein transport by the Sec complex [GO:0043952]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	bacterial-type flagellum-dependent swarming motility [GO:0071978]; pathogenesis [GO:0009405]; protein secretion by the type II secretion system [GO:0015628]; protein transport by the Sec complex [GO:0043952]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1ezma__d5mnre___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; bacterial-type flagellum-dependent swarming motility [GO:0071978]; pathogenesis [GO:0009405]; protein secretion by the type II secretion system [GO:0015628]; protein transport by the Sec complex [GO:0043952]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	bacterial-type flagellum-dependent swarming motility [GO:0071978]; pathogenesis [GO:0009405]; protein secretion by the type II secretion system [GO:0015628]; protein transport by the Sec complex [GO:0043952]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1ezoa__d3lsfe___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1ezpa__d1olca___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	protein transport [GO:0015031]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	peptide transmembrane transporter activity [GO:1904680]
d1ezra__d3epwb___1					calcium ion binding [GO:0005509]; inosine nucleosidase activity [GO:0047724]; purine nucleosidase activity [GO:0008477]; uridine nucleosidase activity [GO:0045437]; nucleotide metabolic process [GO:0009117]; purine-containing compound salvage [GO:0043101]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	nucleotide metabolic process [GO:0009117]; purine-containing compound salvage [GO:0043101]				calcium ion binding [GO:0005509]; inosine nucleosidase activity [GO:0047724]; purine nucleosidase activity [GO:0008477]; uridine nucleosidase activity [GO:0045437]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1ezsc__d3zvaa1__1			Proteobacteria		outer membrane-bounded periplasmic space [GO:0030288]; serine-type endopeptidase inhibitor activity [GO:0004867]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	outer membrane-bounded periplasmic space [GO:0030288]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase inhibitor activity [GO:0004867]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ezta__d5do9d1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; brain development [GO:0007420]; dorsal root ganglion development [GO:1990791]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of dopamine receptor signaling pathway [GO:0060160]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of glycine import across plasma membrane [GO:1900924]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart rate [GO:0010460]; regulation of actin filament organization [GO:0110053]; regulation of calcium ion transport [GO:0051924]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amphetamine [GO:0001975]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to morphine [GO:0043278]	caveola [GO:0005901]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; alkylglycerophosphoethanolamine phosphodiesterase activity [GO:0047391]; G protein-coupled receptor binding [GO:0001664]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTP binding [GO:0005525]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; type 2A serotonin receptor binding [GO:0031826]; action potential [GO:0001508]; activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; developmental pigmentation [GO:0048066]; embryonic digit morphogenesis [GO:0042733]; forebrain neuron development [GO:0021884]; G protein-coupled receptor signaling pathway [GO:0007186]; glutamate receptor signaling pathway [GO:0007215]; heart development [GO:0007507]; maternal behavior [GO:0042711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein kinase activity [GO:0006469]; neuron remodeling [GO:0016322]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of smooth muscle cell proliferation [GO:0048661]; post-embryonic development [GO:0009791]; protein stabilization [GO:0050821]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of melanocyte differentiation [GO:0045634]; skeletal system development [GO:0001501]	brain development [GO:0007420]; dorsal root ganglion development [GO:1990791]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of dopamine receptor signaling pathway [GO:0060160]; negative regulation of glycine import across plasma membrane [GO:1900924]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart rate [GO:0010460]; regulation of actin filament organization [GO:0110053]; regulation of calcium ion transport [GO:0051924]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amphetamine [GO:0001975]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to morphine [GO:0043278]	action potential [GO:0001508]; activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; developmental pigmentation [GO:0048066]; embryonic digit morphogenesis [GO:0042733]; forebrain neuron development [GO:0021884]; glutamate receptor signaling pathway [GO:0007215]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; maternal behavior [GO:0042711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein kinase activity [GO:0006469]; neuron remodeling [GO:0016322]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of smooth muscle cell proliferation [GO:0048661]; post-embryonic development [GO:0009791]; protein stabilization [GO:0050821]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of melanocyte differentiation [GO:0045634]; skeletal system development [GO:0001501]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	caveola [GO:0005901]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]	alkylglycerophosphoethanolamine phosphodiesterase activity [GO:0047391]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; type 2A serotonin receptor binding [GO:0031826]
d1ezuc__d1vcpb___1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1ezvx__d1aqkl2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ezwa__d1bsla___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity [GO:0018537]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	alkanal monooxygenase (FMN-linked) activity [GO:0047646]; bioluminescence [GO:0008218]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	bioluminescence [GO:0008218]	cytoplasm [GO:0005737]		coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity [GO:0018537]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	alkanal monooxygenase (FMN-linked) activity [GO:0047646]
d1ezya__d2bt2d1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; brain development [GO:0007420]; dorsal root ganglion development [GO:1990791]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of dopamine receptor signaling pathway [GO:0060160]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of glycine import across plasma membrane [GO:1900924]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart rate [GO:0010460]; regulation of actin filament organization [GO:0110053]; regulation of calcium ion transport [GO:0051924]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amphetamine [GO:0001975]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to morphine [GO:0043278]	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; visual perception [GO:0007601]	brain development [GO:0007420]; dorsal root ganglion development [GO:1990791]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of dopamine receptor signaling pathway [GO:0060160]; negative regulation of glycine import across plasma membrane [GO:1900924]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart rate [GO:0010460]; regulation of actin filament organization [GO:0110053]; regulation of calcium ion transport [GO:0051924]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amphetamine [GO:0001975]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to morphine [GO:0043278]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; plasma membrane [GO:0005886]	G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]	calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]
d1ezzc1_d2fg7y2__1			Proteobacteria	Bacteroidetes	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]; zinc ion binding [GO:0008270]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	arginine biosynthetic process [GO:0006526]	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]		zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]
d1ezzc1_d3r7lb1__1			Proteobacteria	Firmicutes	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]; zinc ion binding [GO:0008270]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1ezzc2_d2a0fa1__1			Proteobacteria	Proteobacteria	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]; zinc ion binding [GO:0008270]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1f00i1_d1cwva2__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell surface [GO:0009986]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]		
d1f02i1_d1e1ba1__1			Proteobacteria		cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]			
d1f02i1_d2zwke1__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]		
d1f02i2_d3ncxb1__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]		
d1f04a__d1iccd___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	oxidation-reduction process [GO:0055114]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1f0jb__d5u7jc___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d1f0la2_d4l7oa2__1		Metazoa		Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; catalytic activity [GO:0003824]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]		DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]	identical protein binding [GO:0042802]; NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]	catalytic activity [GO:0003824]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]
d1f0ma__d3kkab___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; receptor complex [GO:0043235]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; nervous system development [GO:0007399]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	angiogenesis [GO:0001525]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; nervous system development [GO:0007399]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; receptor complex [GO:0043235]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]
d1f0ua__d1te0b2__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1f0xa2_d2vfva1__1			Proteobacteria	Actinobacteria	extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor [GO:0016901]; quinone binding [GO:0048038]; aerobic respiration [GO:0009060]; anaerobic respiration [GO:0009061]; lactate oxidation [GO:0019516]; respiratory electron transport chain [GO:0022904]; transmembrane transport [GO:0055085]	membrane [GO:0016020]; D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]	aerobic respiration [GO:0009060]; anaerobic respiration [GO:0009061]; lactate oxidation [GO:0019516]; respiratory electron transport chain [GO:0022904]; transmembrane transport [GO:0055085]		extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	membrane [GO:0016020]	electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor [GO:0016901]; quinone binding [GO:0048038]	D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]
d1f11a2_d1otsf2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1f11a2_d2vlre1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1f11c1_d1ohqa___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1f11c1_d4r7dj2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1f11d1_d1keml1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1f11d2_d4o58l1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1f12b1_d2d3tb2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	fatty acid beta-oxidation [GO:0006635]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d1f12b2_d3dafa1__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	N5,N10-methenyltetrahydromethanopterin hydrogenase activity [GO:0047068]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]		3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]	N5,N10-methenyltetrahydromethanopterin hydrogenase activity [GO:0047068]
d1f13a2_d1evua3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1f15a__d1cwpb___1					T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]			T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1f1ba1_d1za1a2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1f1bc1_d1acma2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1f1bc2_d3r7fa2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1f1ga__d1funi___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1f1gf__d1hl5j___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1f1ha1_d4lnil1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1f1hb1_d2whic1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1f1hc1_d4lnfb1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1f1hd1_d2glsg1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d1f1hd2_d2whic2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1f1he1_d4lnoa1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1f1he2_d1m15a2__1		Metazoa	Proteobacteria	Arthropoda	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d1f1hf2_d3l2fi2__1			Proteobacteria		cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	
d1f1hj2_d1htok2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1f1hk2_d3qajh2__1			Proteobacteria		cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	
d1f1hl2_d3zxvf2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1f1ma__d1yjga___1			Spirochaetes	Spirochaetes	cell outer membrane [GO:0009279]; metal ion binding [GO:0046872]	cell outer membrane [GO:0009279]			cell outer membrane [GO:0009279]	cell outer membrane [GO:0009279]	metal ion binding [GO:0046872]	
d1f1md__d2ga0d___1			Spirochaetes	Spirochaetes	cell outer membrane [GO:0009279]; metal ion binding [GO:0046872]	cell outer membrane [GO:0009279]			cell outer membrane [GO:0009279]	cell outer membrane [GO:0009279]	metal ion binding [GO:0046872]	
d1f1rb1_d2igaa1__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1f1sa1_d1hmua1__1			Firmicutes	Bacteroidetes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]
d1f1sa4_d3czsa2__1		Metazoa	Firmicutes	Arthropoda	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1f1xc1_d2ei2a2__1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	1,2-dihydroxynaphthalene dioxygenase activity [GO:0018554]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; naphthalene catabolic process [GO:1901170]		naphthalene catabolic process [GO:1901170]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	1,2-dihydroxynaphthalene dioxygenase activity [GO:0018554]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d1f1ya1_d2ig9d2__1				Actinobacteria		dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]						dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1f1yb1_d1gdga4__1												
d1f20a2_d3w5ua2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]; ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]	chloroplast thylakoid membrane protein complex [GO:0098807]	ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d1f24a__d5b2ub___1	Fungi		Ascomycota	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d1f25a__d5ofqd___1	Fungi		Ascomycota	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1f26a__d3cxva___1	Fungi		Ascomycota	Actinobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]
d1f28a__d2kceb___1	Fungi		Ascomycota	Proteobacteria	thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]		cytosol [GO:0005829]	thymidylate synthase activity [GO:0004799]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]
d1f28a__d4irra___1	Fungi	Metazoa	Ascomycota	Nematoda (roundworms)	thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]			thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d1f29c__d1qolg___1					cysteine-type endopeptidase activity [GO:0004197]	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cysteine-type endopeptidase activity [GO:0004197]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1f2aa__d4jkja___1		Metazoa		Chordata	cysteine-type endopeptidase activity [GO:0004197]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; adult walking behavior [GO:0007628]; axon target recognition [GO:0007412]; axonal transport of mitochondrion [GO:0019896]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]		adult walking behavior [GO:0007628]; axonal transport of mitochondrion [GO:0019896]; axon target recognition [GO:0007412]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]		axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]	cysteine-type endopeptidase activity [GO:0004197]	alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]
d1f2ba__d1nudb4__1		Metazoa		Chordata	cysteine-type endopeptidase activity [GO:0004197]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]		cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	cysteine-type endopeptidase activity [GO:0004197]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]
d1f2ca__d4bs5a___1		Metazoa		Chordata	cysteine-type endopeptidase activity [GO:0004197]	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]		antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]		cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]	cysteine-type endopeptidase activity [GO:0004197]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]
d1f2dd1_d3zeia___1	Fungi		Ascomycota	Actinobacteria	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	amine catabolic process [GO:0009310]	cysteine biosynthetic process from serine [GO:0006535]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]
d1f2dd1_d4y6gb___1	Fungi		Ascomycota	Proteobacteria	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	amine catabolic process [GO:0009310]	tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]
d1f2ea1_d2vo4a2__1		Viridiplantae	Proteobacteria	Streptophyta	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]					glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1f2eb1_d3vwxb2__1		Metazoa	Proteobacteria	Arthropoda	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]					glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1f2ec2_d1yj6c2__1		Metazoa	Proteobacteria	Chordata	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	glutathione transferase activity [GO:0004364]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d1f2ec2_d4k7ib___1		Metazoa	Proteobacteria	Chordata	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	glutathione transferase activity [GO:0004364]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]
d1f2ka__d5fegb___1		Viridiplantae		Streptophyta	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; protein self-association [GO:0043621]			cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]	actin binding [GO:0003779]; protein self-association [GO:0043621]
d1f2ma__d3tp7a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1f2na__d1yc6m___1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1f2nb__d4rqpc___1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1f2nb__d4y5zf___1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	viral capsid [GO:0019028]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1f2qa2_d1wwbx___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	axon [GO:0030424]; axon terminus [GO:0043679]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; brain-derived neurotrophic factor binding [GO:0048403]; brain-derived neurotrophic factor-activated receptor activity [GO:0060175]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of phospholipase C activity [GO:0007202]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cellular response to amino acid stimulus [GO:0071230]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; circadian rhythm [GO:0007623]; feeding behavior [GO:0007631]; glutamate secretion [GO:0014047]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuronal action potential propagation [GO:0019227]; neurotrophin TRK receptor signaling pathway [GO:0048011]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system neuron development [GO:0048935]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; retinal rod cell development [GO:0046548]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trans-synaptic signaling by neuropeptide, modulating synaptic transmission [GO:0099551]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	Fc-epsilon receptor signaling pathway [GO:0038095]	activation of phospholipase C activity [GO:0007202]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cellular response to amino acid stimulus [GO:0071230]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; circadian rhythm [GO:0007623]; feeding behavior [GO:0007631]; glutamate secretion [GO:0014047]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neuronal action potential propagation [GO:0019227]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neurotrophin TRK receptor signaling pathway [GO:0048011]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system neuron development [GO:0048935]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; retinal rod cell development [GO:0046548]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trans-synaptic signaling by neuropeptide, modulating synaptic transmission [GO:0099551]; vasculogenesis [GO:0001570]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	axon [GO:0030424]; axon terminus [GO:0043679]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	IgE binding [GO:0019863]	ATP binding [GO:0005524]; brain-derived neurotrophic factor-activated receptor activity [GO:0060175]; brain-derived neurotrophic factor binding [GO:0048403]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1f2qa2_d2clzp___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	Fc-epsilon receptor signaling pathway [GO:0038095]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	IgE binding [GO:0019863]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1f2xk__d4llab2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cell adhesion molecule binding [GO:0050839]; inhibitory MHC class I receptor activity [GO:0032396]; MHC class I protein binding [GO:0042288]; MHC class Ib protein binding [GO:0023029]; MHC class Ib protein complex binding [GO:0023025]; protein homodimerization activity [GO:0042803]; protein phosphatase 1 binding [GO:0008157]; protein-containing complex binding [GO:0044877]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; cellular response to lipopolysaccharide [GO:0071222]; Fc receptor mediated inhibitory signaling pathway [GO:0002774]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; immune response-inhibiting cell surface receptor signaling pathway [GO:0002767]; learning or memory [GO:0007611]; negative regulation of antigen processing and presentation [GO:0002578]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of postsynaptic density organization [GO:1905875]; negative regulation of protein metabolic process [GO:0051248]; negative regulation of T cell proliferation [GO:0042130]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T cell tolerance induction [GO:0002666]; positive regulation of tolerance induction [GO:0002645]; regulation of dendritic cell differentiation [GO:2001198]; regulation of immune response [GO:0050776]; regulation of long-term synaptic potentiation [GO:1900271]; signal transduction [GO:0007165]		adaptive immune response [GO:0002250]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to lipopolysaccharide [GO:0071222]; Fc receptor mediated inhibitory signaling pathway [GO:0002774]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; immune response-inhibiting cell surface receptor signaling pathway [GO:0002767]; learning or memory [GO:0007611]; negative regulation of antigen processing and presentation [GO:0002578]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of postsynaptic density organization [GO:1905875]; negative regulation of protein metabolic process [GO:0051248]; negative regulation of T cell proliferation [GO:0042130]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T cell tolerance induction [GO:0002666]; positive regulation of tolerance induction [GO:0002645]; regulation of dendritic cell differentiation [GO:2001198]; regulation of immune response [GO:0050776]; regulation of long-term synaptic potentiation [GO:1900271]; signal transduction [GO:0007165]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]		amyloid-beta binding [GO:0001540]; cell adhesion molecule binding [GO:0050839]; inhibitory MHC class I receptor activity [GO:0032396]; MHC class Ib protein binding [GO:0023029]; MHC class Ib protein complex binding [GO:0023025]; MHC class I protein binding [GO:0042288]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; protein phosphatase 1 binding [GO:0008157]
d1f30b__d3qb9c___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1f30c__d4zttf1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1f30e__d4to9b___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1f30i__d2jd6e___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d1f30j__d4xgse1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1f31a2_d5dzua___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	vacuole [GO:0005773]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; serine-type endopeptidase inhibitor activity [GO:0004867]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	vacuole [GO:0005773]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase inhibitor activity [GO:0019828]; serine-type endopeptidase inhibitor activity [GO:0004867]
d1f33a__d1tjoa___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytoplasm [GO:0005737]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d1f33b__d5ww9a___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1f33f__d1z6oq___1		Metazoa	Proteobacteria	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1f33f__d4dasb___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1f33g__d5d8pl___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1f33h__d3a68n___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1f33k__d5ww5d___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1f37a__d1m2db___1			Aquificae	Aquificae	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]			2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]
d1f37b__d1m2da___1			Aquificae	Aquificae	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]			2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]
d1f3ab1_d4acsd2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; steroid delta-isomerase activity [GO:0004769]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d1f3ab1_d5d9xa2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; steroid delta-isomerase activity [GO:0004769]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; ascorbate glutathione cycle [GO:0033355]; cellular oxidant detoxification [GO:0098869]; protein glutathionylation [GO:0010731]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]	ascorbate glutathione cycle [GO:0033355]; cellular oxidant detoxification [GO:0098869]; protein glutathionylation [GO:0010731]	cytosol [GO:0005829]	cytosol [GO:0005829]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; steroid delta-isomerase activity [GO:0004769]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]
d1f3dh1_d1dsfh___1	Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d1f3dh1_d3sgja1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	IgG binding [GO:0019864]
d1f3dk1_d1mlca1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1f3dk2_d1q1jm1__1	Metazoa		Chordata		metal ion binding [GO:0046872]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1f3dk2_d1s7xk___1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1f3fa__d1f6ta___1					cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1f3ja1_d5gs1q___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1f3jb2_d3gsoa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1f3je1_d1yehh1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1f3je2_d2zokg2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1f3rb1_d1sjhb1__1		Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1f3xc3_d1f3wg3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	positive regulation of sprouting angiogenesis [GO:1903672]	positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1f3xe3_d1f3wh3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	positive regulation of sprouting angiogenesis [GO:1903672]	positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1f3xg3_d3hqpa3__1	Metazoa		Chordata		cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	positive regulation of sprouting angiogenesis [GO:1903672]		cytoplasm [GO:0005737]; nucleus [GO:0005634]		ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1f40a__d3ni6a___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]		cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]		activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1f47b__d1f7xa___1			Proteobacteria	Proteobacteria	cell division site [GO:0032153]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]	cell division site [GO:0032153]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]	division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]	division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]	cell division site [GO:0032153]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell division site [GO:0032153]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		
d1f49a1_d3dypd4__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1f49b1_d2vzsa3__1				Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1f49b3_d2j1va___1				Firmicutes		metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				metal ion binding [GO:0046872]
d1f49c1_d4duxc4__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1f49c2_d2vzvb5__1				Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1f49d1_d1jz7d2__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1f49d1_d3dyod4__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1f49e2_d3k4db2__1				Proteobacteria		cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]		glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]		cytosol [GO:0005829]		beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d1f49f3_d1nx9c1__1				Proteobacteria		alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]						alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d1f49h3_d1yq2b3__1				Actinobacteria		beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		beta-galactosidase complex [GO:0009341]		beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1f4aa4_d2e24a3__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	lactose catabolic process [GO:0005990]	polysaccharide metabolic process [GO:0005976]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]
d1f4aa5_d1v3ja4__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1f4ab1_d3sepd4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1f4ab2_d2vzub5__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1f4ab5_d4zenb___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	6-phospho-beta-galactosidase activity [GO:0033920]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	6-phospho-beta-galactosidase activity [GO:0033920]
d1f4ac4_d1nsua1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1f4ad4_d3sepd5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1f4ad5_d1dedb4__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1f4ha1_d3vd7b4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1f4ha2_d1jz6a1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1f4ha3_d1uloa___1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cellulase activity [GO:0008810]
d1f4ha4_d3buba2__1		Metazoa	Proteobacteria	Arthropoda	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1f4ha5_d3hn3d3__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	beta-galactosidase complex [GO:0009341]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]
d1f4hc5_d1fcua___1		Metazoa	Proteobacteria	Arthropoda	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; hyalurononglucosaminidase activity [GO:0004415]; carbohydrate metabolic process [GO:0005975]; defense response [GO:0006952]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; defense response [GO:0006952]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	hyalurononglucosaminidase activity [GO:0004415]
d1f4hd2_d3dyod2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1f4kb__d4hqmb___1			Firmicutes		DNA binding [GO:0003677]; DNA replication termination [GO:0006274]		DNA replication termination [GO:0006274]				DNA binding [GO:0003677]	
d1f4ob__d4l79b___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; membrane fusion [GO:0061025]; neutrophil degranulation [GO:0043312]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	membrane fusion [GO:0061025]; neutrophil degranulation [GO:0043312]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1f4qb__d5pala___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; membrane fusion [GO:0061025]; neutrophil degranulation [GO:0043312]	calcium ion binding [GO:0005509]	membrane fusion [GO:0061025]; neutrophil degranulation [GO:0043312]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]
d1f4tb__d3t3se___1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d1f4ub__d1dz8a___1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1f4va__d5brja___1			Proteobacteria		cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	
d1f4vc__d3eqzb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	
d1f4xl2_d5c2bl___1		Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d1f4yh2_d3vi3l2__1		Metazoa		Chordata		alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integrin alpha5-beta1 complex [GO:0034674]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]; epidermal growth factor receptor binding [GO:0005154]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor receptor binding [GO:0005161]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; angiogenesis [GO:0001525]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory [GO:0007613]; negative regulation of anoikis [GO:2000811]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; wound healing, spreading of epidermal cells [GO:0035313]		angiogenesis [GO:0001525]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory [GO:0007613]; negative regulation of anoikis [GO:2000811]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; wound healing, spreading of epidermal cells [GO:0035313]		alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integrin alpha5-beta1 complex [GO:0034674]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]		epidermal growth factor receptor binding [GO:0005154]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor receptor binding [GO:0005161]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]
d1f51f__d1qo0d___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	amide binding [GO:0033218]; kinase activity [GO:0016301]; amino acid transport [GO:0006865]; negative regulation of hydrolase activity [GO:0051346]; regulation of cellular amide catabolic process [GO:0034251]	phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	amino acid transport [GO:0006865]; negative regulation of hydrolase activity [GO:0051346]; regulation of cellular amide catabolic process [GO:0034251]	cytoplasm [GO:0005737]		kinase activity [GO:0016301]; metal ion binding [GO:0046872]	amide binding [GO:0033218]; kinase activity [GO:0016301]
d1f52c2_d1htoh2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1f52d1_d4lnna1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1f52e2_d1htqh2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1f52f1_d3zxrd1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1f52g2_d1htqn2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1f52j1_d4lnod1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1f52l1_d2glsa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d1f52l2_d1htov2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1f52l2_d4acfc2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1f56a__d2jfca1__1	Viridiplantae		Streptophyta	Proteobacteria	electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]			electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1f56b__d1v54b1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	electron transfer activity [GO:0009055]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]		ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1f56b__d2cj3a___1	Viridiplantae		Streptophyta	Cyanobacteria	electron transfer activity [GO:0009055]	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				thylakoid membrane [GO:0042651]	electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1f58h1_d4om0l1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1f58h2_d4kv5i1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; antigen binding [GO:0003823]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; aortic valve morphogenesis [GO:0003180]; ATP biosynthetic process [GO:0006754]; BMP signaling pathway [GO:0030509]; cell cycle arrest [GO:0007050]; cell development [GO:0048468]; cell migration [GO:0016477]; cell-cell junction organization [GO:0045216]; cellular response to organic cyclic compound [GO:0071407]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chondrocyte differentiation [GO:0002062]; common-partner SMAD protein phosphorylation [GO:0007182]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; embryonic liver development [GO:1990402]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial to mesenchymal transition [GO:0001837]; evasion or tolerance of host defenses by virus [GO:0019049]; extracellular matrix assembly [GO:0085029]; extrinsic apoptotic signaling pathway [GO:0097191]; heart development [GO:0007507]; heart valve morphogenesis [GO:0003179]; hematopoietic progenitor cell differentiation [GO:0002244]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymph node development [GO:0048535]; macrophage derived foam cell differentiation [GO:0010742]; MAPK cascade [GO:0000165]; membrane protein intracellular domain proteolysis [GO:0031293]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cytolysis [GO:0045918]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of skeletal muscle tissue development [GO:0048642]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; ossification involved in bone remodeling [GO:0043932]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; phosphate-containing compound metabolic process [GO:0006796]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of chemotaxis [GO:0050921]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglia differentiation [GO:0014008]; positive regulation of NAD+ ADP-ribosyltransferase activity [GO:1901666]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular permeability [GO:0043117]; protein export from nucleus [GO:0006611]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor catabolic process [GO:0032801]; regulation of apoptotic process [GO:0042981]; regulation of binding [GO:0051098]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of DNA binding [GO:0051101]; regulation of MAPK cascade [GO:0043408]; regulation of protein import into nucleus [GO:0042306]; regulation of SMAD protein signal transduction [GO:0060390]; regulation of striated muscle tissue development [GO:0016202]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; salivary gland morphogenesis [GO:0007435]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transforming growth factor beta receptor signaling pathway involved in heart development [GO:1905313]; vasculogenesis [GO:0001570]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	aortic valve morphogenesis [GO:0003180]; ATP biosynthetic process [GO:0006754]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell cycle arrest [GO:0007050]; cell development [GO:0048468]; cell migration [GO:0016477]; cellular response to organic cyclic compound [GO:0071407]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chondrocyte differentiation [GO:0002062]; common-partner SMAD protein phosphorylation [GO:0007182]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; embryonic liver development [GO:1990402]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial to mesenchymal transition [GO:0001837]; evasion or tolerance of host defenses by virus [GO:0019049]; extracellular matrix assembly [GO:0085029]; extrinsic apoptotic signaling pathway [GO:0097191]; heart development [GO:0007507]; heart valve morphogenesis [GO:0003179]; hematopoietic progenitor cell differentiation [GO:0002244]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymph node development [GO:0048535]; macrophage derived foam cell differentiation [GO:0010742]; MAPK cascade [GO:0000165]; membrane protein intracellular domain proteolysis [GO:0031293]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytolysis [GO:0045918]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of skeletal muscle tissue development [GO:0048642]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; ossification involved in bone remodeling [GO:0043932]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; phosphate-containing compound metabolic process [GO:0006796]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of chemotaxis [GO:0050921]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglia differentiation [GO:0014008]; positive regulation of NAD+ ADP-ribosyltransferase activity [GO:1901666]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular permeability [GO:0043117]; protein export from nucleus [GO:0006611]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor catabolic process [GO:0032801]; regulation of apoptotic process [GO:0042981]; regulation of binding [GO:0051098]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of DNA binding [GO:0051101]; regulation of MAPK cascade [GO:0043408]; regulation of protein import into nucleus [GO:0042306]; regulation of SMAD protein signal transduction [GO:0060390]; regulation of striated muscle tissue development [GO:0016202]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; salivary gland morphogenesis [GO:0007435]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transforming growth factor beta receptor signaling pathway involved in heart development [GO:1905313]; vasculogenesis [GO:0001570]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]
d1f59b__d4mkta3__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; enzyme binding [GO:0019899]; Hsp90 protein binding [GO:0051879]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein domain specific binding [GO:0019904]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; apoptotic DNA fragmentation [GO:0006309]; astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; intracellular transport of virus [GO:0075733]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; modulation by virus of host cellular process [GO:0019054]; neutrophil degranulation [GO:0043312]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal protein import into nucleus [GO:0006610]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	apoptotic DNA fragmentation [GO:0006309]; astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; intracellular transport of virus [GO:0075733]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; modulation by virus of host cellular process [GO:0019054]; neutrophil degranulation [GO:0043312]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal protein import into nucleus [GO:0006610]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	enzyme binding [GO:0019899]; Hsp90 protein binding [GO:0051879]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein domain specific binding [GO:0019904]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1f5aa4_d1tfwc2__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; regulation of mRNA 3'-end processing [GO:0031440]; RNA polyadenylation [GO:0043631]	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA polyadenylation [GO:0006378]; regulation of mRNA 3'-end processing [GO:0031440]; RNA polyadenylation [GO:0043631]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]
d1f5ia__d1k8fc___1		Metazoa		Chordata		azurophil granule lumen [GO:0035578]; cortical actin cytoskeleton [GO:0030864]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]; actin polymerization or depolymerization [GO:0008154]; activation of adenylate cyclase activity [GO:0007190]; ameboidal-type cell migration [GO:0001667]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; neutrophil degranulation [GO:0043312]; receptor-mediated endocytosis [GO:0006898]; signal transduction [GO:0007165]		actin polymerization or depolymerization [GO:0008154]; activation of adenylate cyclase activity [GO:0007190]; ameboidal-type cell migration [GO:0001667]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; neutrophil degranulation [GO:0043312]; receptor-mediated endocytosis [GO:0006898]; signal transduction [GO:0007165]		azurophil granule lumen [GO:0035578]; cortical actin cytoskeleton [GO:0030864]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]		actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]
d1f5ja__d1len.1__1		Viridiplantae	Dictyoglomi	Streptophyta	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]; carbohydrate mediated signaling [GO:0009756]	xylan catabolic process [GO:0045493]	carbohydrate mediated signaling [GO:0009756]			carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]
d1f5ja__d4xpva___1		Fungi	Dictyoglomi	Ascomycota	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d1f5ma__d3ksga___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]; cellular response to oxidative stress [GO:0034599]		cellular response to oxidative stress [GO:0034599]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]	
d1f5ob__d1hv4b___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1f5oc__d1hhob___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1f5pa__d3gqga___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1f5pf__d1ch1a___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1f5qb2_d4ogrb1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	ELL-EAF complex [GO:0032783]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription elongation factor complex [GO:0008023]; transcriptionally active chromatin [GO:0035327]; DNA-binding transcription factor activity [GO:0003700]; double-stranded DNA binding [GO:0003690]; spermatid development [GO:0007286]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	spermatid development [GO:0007286]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ELL-EAF complex [GO:0032783]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	DNA-binding transcription factor activity [GO:0003700]; double-stranded DNA binding [GO:0003690]
d1f5qd1_d1h28b2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1f5sb__d1rlmb___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; phosphoserine phosphatase activity [GO:0004647]; dephosphorylation [GO:0016311]; L-serine biosynthetic process [GO:0006564]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	dephosphorylation [GO:0016311]; L-serine biosynthetic process [GO:0006564]		cytoplasm [GO:0005737]	cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; phosphoserine phosphatase activity [GO:0004647]	magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]
d1f5wa__d1oayj___1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d1f5wb__d2jelh1__1	Metazoa		Chordata	Proteobacteria	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]; enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]
d1f5wb__d3mj8l1__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d1f5zd__d3i7sa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	cytosol [GO:0005829]	N-acetylneuraminate lyase activity [GO:0008747]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]
d1f60a1_d2j03e1__1	Fungi		Ascomycota		cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]		maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]		cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]		guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]	
d1f60a2_d3p3mb3__1	Fungi		Ascomycota		cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]		maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]		cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]		guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]	
d1f60a3_d3tvdb___1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endosome [GO:0005768]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; membrane [GO:0016020]; midbody [GO:0030496]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to progesterone stimulus [GO:0071393]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of neuron projection development [GO:0010977]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; positive regulation of vasoconstriction [GO:0045907]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of modification of synaptic structure [GO:1905244]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; trabecula morphogenesis [GO:0061383]; wound healing, spreading of cells [GO:0044319]	maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to progesterone stimulus [GO:0071393]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of cell death [GO:0060548]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of neuron projection development [GO:0010977]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; positive regulation of vasoconstriction [GO:0045907]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of modification of synaptic structure [GO:1905244]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; trabecula morphogenesis [GO:0061383]; wound healing, spreading of cells [GO:0044319]	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endosome [GO:0005768]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; membrane [GO:0016020]; midbody [GO:0030496]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]	guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d1f65a__d3pi4b___1	Metazoa	Metazoa	Chordata	Mollusca	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1f66b__d1u35h___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; nucleosome assembly [GO:0006334]		nucleosome assembly [GO:0006334]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1f66e__d1p3bg___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1f6aa1_d1n6ql1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1f6fb1_d2dtge1__1	Metazoa		Chordata		extracellular region [GO:0005576]; hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]				extracellular region [GO:0005576]		hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]	
d1f6ka__d3oexa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		N-acetylneuraminate lyase activity [GO:0008747]	3-dehydroquinate dehydratase activity [GO:0003855]
d1f6ka__d5kzee___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]	cytosol [GO:0005829]	N-acetylneuraminate lyase activity [GO:0008747]	N-acetylneuraminate lyase activity [GO:0008747]
d1f6mc__d3m9jb___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d1f6mg__d1cqha___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d1f6mh__d2h6yb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1f6pa__d2qjib___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; aromatic amino acid family biosynthetic process [GO:0009073]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	aromatic amino acid family biosynthetic process [GO:0009073]	cytosol [GO:0005829]		N-acetylneuraminate lyase activity [GO:0008747]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]
d1f6rb__d1dyfa___1	Metazoa		Chordata		extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]	lysozyme activity [GO:0003796]
d1f6rb__d1uiba___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1f6rd__d1l21a___1	Metazoa		Chordata		extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]	lysozyme activity [GO:0003796]
d1f6sa__d2rbna___1	Metazoa		Chordata		extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]	lysozyme activity [GO:0003796]
d1f6tc__d4uohc___1		Metazoa		Arthropoda	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d1f74a__d2qdga___1			Proteobacteria		cytosol [GO:0005829]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	glycolytic process [GO:0006096]	cytosol [GO:0005829]		N-acetylneuraminate lyase activity [GO:0008747]	fructose-bisphosphate aldolase activity [GO:0004332]
d1f77a2_d2ipkd2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	extracellular region [GO:0005576]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1f7aa__d5p7da___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1f7ab__d1er8e___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1f7da__d5vjya1__1				Heterolobosea	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1f7db__d3ehwc___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]		extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d1f7kb__d2okda___1					aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1f7oc__d4apzb___1				Firmicutes	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1f7pa__d1duda1__1				Proteobacteria	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1f7pa__d4xjcc___1				Firmicutes	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]			aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d1f7pb__d1q5ux1__1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]		extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d1f7tc1_d5cxdb1__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]	holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]
d1f7ua1_d4zt4b2__1	Fungi		Ascomycota		cytosol [GO:0005829]; mitochondrion [GO:0005739]; arginine-tRNA ligase activity [GO:0004814]; ATP binding [GO:0005524]; arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543]	methionyl-tRNA aminoacylation [GO:0006431]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	arginine-tRNA ligase activity [GO:0004814]; ATP binding [GO:0005524]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]
d1f7va3_d1bs2a3__1	Fungi	Fungi	Ascomycota	Ascomycota	cytosol [GO:0005829]; mitochondrion [GO:0005739]; arginine-tRNA ligase activity [GO:0004814]; ATP binding [GO:0005524]; arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; arginine-tRNA ligase activity [GO:0004814]; ATP binding [GO:0005524]; arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543]	arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543]	arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	arginine-tRNA ligase activity [GO:0004814]; ATP binding [GO:0005524]	arginine-tRNA ligase activity [GO:0004814]; ATP binding [GO:0005524]
d1f80c__d1f80b___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]	holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]
d1f86b__d1e4ha___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1f8da__d3o9ka___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1f8ia__d1sgjb___1			Actinobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]; zymogen binding [GO:0035375]; cellular response to hypoxia [GO:0071456]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; maintenance of symbiont tolerance to host environment [GO:0075141]; pathogenesis [GO:0009405]; response to acetate [GO:0010034]; response to acidic pH [GO:0010447]; response to fatty acid [GO:0070542]; response to host immune response [GO:0052572]; tricarboxylic acid cycle [GO:0006099]	lyase activity [GO:0016829]; magnesium ion binding [GO:0000287]; oxaloacetate metabolic process [GO:0006107]	cellular response to hypoxia [GO:0071456]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; maintenance of symbiont tolerance to host environment [GO:0075141]; pathogenesis [GO:0009405]; response to acetate [GO:0010034]; response to acidic pH [GO:0010447]; response to fatty acid [GO:0070542]; response to host immune response [GO:0052572]; tricarboxylic acid cycle [GO:0006099]	oxaloacetate metabolic process [GO:0006107]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]; zymogen binding [GO:0035375]	lyase activity [GO:0016829]; magnesium ion binding [GO:0000287]
d1f8rc2_d1ddob2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	extracellular region [GO:0005576]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d1f8sa2_d1b37a2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	extracellular region [GO:0005576]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]
d1f8sa2_d1ddoc2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	extracellular region [GO:0005576]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d1f8sd2_d1lv0a2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; midbody [GO:0030496]; GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]; negative regulation of axonogenesis [GO:0050771]; negative regulation of protein targeting to membrane [GO:0090315]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	negative regulation of axonogenesis [GO:0050771]; negative regulation of protein targeting to membrane [GO:0090315]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; midbody [GO:0030496]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]	GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]
d1f8sd2_d1s3ba2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	extracellular region [GO:0005576]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1f8se2_d1c0la2__1	Metazoa	Fungi	Chordata	Basidiomycota	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	peroxisome [GO:0005777]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; D-amino acid metabolic process [GO:0046416]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	D-amino acid metabolic process [GO:0046416]	extracellular region [GO:0005576]	peroxisome [GO:0005777]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]
d1f8sf2_d5mrlb2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	extracellular region [GO:0005576]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1f8sg2_d2gf3a2__1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	tetrahydrofolate metabolic process [GO:0046653]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]	sarcosine oxidase activity [GO:0008115]
d1f8sh2_d1k0ia2__1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	benzoate catabolic process via hydroxylation [GO:0043640]	extracellular region [GO:0005576]		L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1f8th1_d5wlgd1__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1f8tl1_d4np4m1__1				Firmicutes		host cell plasma membrane [GO:0020002]; cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		host cell plasma membrane [GO:0020002]		cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]
d1f8tl2_d5d7ih1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1f8yb__d1ishb___1		Metazoa	Firmicutes	Chordata	nucleoside deoxyribosyltransferase activity [GO:0050144]; nucleotide salvage [GO:0043173]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]; ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	nucleotide salvage [GO:0043173]	humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]		anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]	nucleoside deoxyribosyltransferase activity [GO:0050144]	ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d1f90h2_d4fz8l1__1												
d1f90l1_d1aj7h2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1f90l1_d3or6a1__1				Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1f90l2_d4k07a___1		Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d1f91a1_d3v4nc2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	isoprenoid biosynthetic process [GO:0008299]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d1f91a2_d1u0ud2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	pinosylvin synthase activity [GO:0050198]
d1f91c1_d1og8a3__1			Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	
d1f91c2_d2wgfg2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytosol [GO:0005829]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]
d1f91d2_d4yuca1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1f97a1_d4uimb2__1	Metazoa		Chordata		bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasmic vesicle [GO:0031410]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; actomyosin structure organization [GO:0031032]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; epithelial cell differentiation [GO:0030855]; establishment of endothelial intestinal barrier [GO:0090557]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]		actomyosin structure organization [GO:0031032]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; epithelial cell differentiation [GO:0030855]; establishment of endothelial intestinal barrier [GO:0090557]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]		bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasmic vesicle [GO:0031410]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]		integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]	
d1f98a__d3c2wg3__1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d1f99a__d1y46b___1		Metazoa	Rhodophyta	Chordata	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1f99b__d5b13k___1			Rhodophyta	Rhodophyta	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]		
d1f99l__d3vrec___1		Metazoa	Rhodophyta	Chordata	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1f9cb1_d2zc8b2__1			Proteobacteria	Deinococcus-Thermus	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	cellular amino acid catabolic process [GO:0009063]	menaquinone biosynthetic process [GO:0009234]			chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d1f9da__d4xwma___1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			cellulase activity [GO:0008810]	cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; metal ion binding [GO:0046872]
d1f9ga1_d1n7qa1__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d1f9ha__d5etna___1			Proteobacteria	Proteobacteria	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]			2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]
d1f9mb__d1xw9a___1	Viridiplantae	Metazoa	Streptophyta	Arthropoda	cell [GO:0005623]; chloroplast [GO:0009507]; cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; chloroplast [GO:0009507]	cell [GO:0005623]; nucleus [GO:0005634]		disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]
d1f9mb__d5f0gb1__1	Viridiplantae	Metazoa	Streptophyta	Arthropoda	cell [GO:0005623]; chloroplast [GO:0009507]; cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]; chloroplast [GO:0009507]	cytoplasm [GO:0005737]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]
d1f9na2_d3bueb___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1f9nb1_d1b4aa1__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1f9nb2_d1b4ab2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1f9ra__d1qnkb___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]; chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; chemokine activity [GO:0008009]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; neutrophil chemotaxis [GO:0030593]; response to molecule of bacterial origin [GO:0002237]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; neutrophil chemotaxis [GO:0030593]; response to molecule of bacterial origin [GO:0002237]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]	chemokine activity [GO:0008009]
d1fa0a4_d2pxia3__1	Fungi	Metazoa	Ascomycota	Chordata	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d1fa2a__d1cgua4__1	Viridiplantae		Streptophyta	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1fa3a__d1stfi___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta		cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]						cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]
d1fada__d3ezqf___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cardiac muscle tissue development [GO:0048738]; cellular response to mechanical stimulus [GO:0071260]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of necroptotic process [GO:0060544]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation [GO:0030217]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity [GO:0097202]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cardiac muscle tissue development [GO:0048738]; cellular response to mechanical stimulus [GO:0071260]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of necroptotic process [GO:0060544]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation [GO:0030217]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ripoptosome [GO:0097342]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]
d1faea__d2b4fa___1			Firmicutes	Proteobacteria	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]			cellulase activity [GO:0008810]	endo-1,4-beta-xylanase activity [GO:0031176]
d1fagc__d2fdwb1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d1fagd__d1eh0a___1			Firmicutes		cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]				cytoplasm [GO:0005737]		aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	
d1faha__d1geba___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1faha__d3juva___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]; cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]
d1fahb__d4ejhg___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d1fahb__d5b2xb___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d1fapa__d2zr4a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]
d1fawd__d4wjgb___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1fayb__d1tepd___1	Viridiplantae		Streptophyta		carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]						carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	
d1fayb__d5gm5a___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]
d1fayc__d1v6ne___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1fayd__d4hkoa___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d1fayd__d5cnad___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1faye__d2d3ra___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1fb0a__d4weta___1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; chloroplast [GO:0009507]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; chloroplast [GO:0009507]	cell [GO:0005623]; periplasmic space [GO:0042597]	protein disulfide oxidoreductase activity [GO:0015035]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]
d1fb0b__d1gnwb2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cell [GO:0005623]; chloroplast [GO:0009507]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell [GO:0005623]; chloroplast [GO:0009507]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	protein disulfide oxidoreductase activity [GO:0015035]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d1fb1c__d1vaxc2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]	
d1fb1d__d1vaxd2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]	
d1fb1e__d1fbxe___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1fb1e__d5m98c1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1fb3a3_d4f7da1__1				Proteobacteria		ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]						ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1fb3b3_d5vw6a1__1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]				chloroplast [GO:0009507]		ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1fb6a__d2h76b___1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; chloroplast [GO:0009507]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; chloroplast [GO:0009507]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1fbaa__d3ndob___1	Metazoa		Arthropoda	Actinobacteria	cytosol [GO:0005829]; M band [GO:0031430]; Z disc [GO:0030018]; fructose-bisphosphate aldolase activity [GO:0004332]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; mesoderm development [GO:0007498]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	fructose 1,6-bisphosphate metabolic process [GO:0030388]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; mesoderm development [GO:0007498]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytosol [GO:0005829]; M band [GO:0031430]; Z disc [GO:0030018]	cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	deoxyribose-phosphate aldolase activity [GO:0004139]
d1fbab__d1j2wd___1	Metazoa		Arthropoda	Deinococcus-Thermus	cytosol [GO:0005829]; M band [GO:0031430]; Z disc [GO:0030018]; fructose-bisphosphate aldolase activity [GO:0004332]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; mesoderm development [GO:0007498]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	fructose 1,6-bisphosphate metabolic process [GO:0030388]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; mesoderm development [GO:0007498]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytosol [GO:0005829]; M band [GO:0031430]; Z disc [GO:0030018]	cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	deoxyribose-phosphate aldolase activity [GO:0004139]
d1fbac__d3kofb___1	Metazoa		Arthropoda	Proteobacteria	cytosol [GO:0005829]; M band [GO:0031430]; Z disc [GO:0030018]; fructose-bisphosphate aldolase activity [GO:0004332]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; mesoderm development [GO:0007498]	cytosol [GO:0005829]; membrane [GO:0016020]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	fructose 1,6-bisphosphate metabolic process [GO:0030388]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; mesoderm development [GO:0007498]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytosol [GO:0005829]; M band [GO:0031430]; Z disc [GO:0030018]	cytosol [GO:0005829]; membrane [GO:0016020]	fructose-bisphosphate aldolase activity [GO:0004332]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]
d1fbih1_d1n7mh2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fbil1_d4rzch___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fbil2_d2xknc1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fbip2_d1y0ll1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fbiq1_d1nd0a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	metal ion binding [GO:0046872]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d1fbiq1_d2iffh2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1fbix__d4lfxa___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1fboa__d1tf4a1__1			Firmicutes	Actinobacteria	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			cellulase activity [GO:0008810]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d1fbxa__d4n9ma1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1fbxb__d2yzec2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1fbxg__d3plga1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1fbxh__d3pkua2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1fbxj__d5m98h1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1fbxk__d1wplb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]
d1fbxk__d2yzbg2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1fbxl__d3pk5a1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1fbxm__d2yzda2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1fbxo__d1wple___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]
d1fc1a1_d2vyrf___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]
d1fc1b2_d5obfl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fc2d2_d3cche___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1fc7a3_d3lnxe___1	Viridiplantae	Metazoa	Chlorophyta	Chordata	chloroplast thylakoid lumen [GO:0009543]; serine-type peptidase activity [GO:0008236]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]		cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	chloroplast thylakoid lumen [GO:0009543]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	serine-type peptidase activity [GO:0008236]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]
d1fcca2_d2yuza1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; myofibril [GO:0030016]; myosin filament [GO:0032982]; actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; myofibril [GO:0030016]; myosin filament [GO:0032982]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]
d1fccb1_d4osul2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fccb1_d5vzyl1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fcea__d2fbaa___1		Fungi	Firmicutes	Ascomycota	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	glucan 1,4-alpha-glucosidase activity [GO:0004339]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]	glucan 1,4-alpha-glucosidase activity [GO:0004339]
d1fcka1_d5hbca___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d1fcka2_d1aiva2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]
d1fd7d__d1ptod___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1fd7m__d1fnwh1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1fd7m__d1rcve___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	toxin activity [GO:0090729]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d1fd7n__d1ha5a1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1fd8a__d1kvja___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; copper chaperone activity [GO:0016531]; cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]; antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cell [GO:0005623]; cytosol [GO:0005829]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	copper chaperone activity [GO:0016531]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]
d1fd8a__d1yjua1__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; copper chaperone activity [GO:0016531]; cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]; antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cell [GO:0005623]; cytosol [GO:0005829]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	copper chaperone activity [GO:0016531]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]
d1fd9a__d5hwbb1__1		Fungi	Proteobacteria	Ascomycota	cell outer membrane [GO:0009279]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; pathogenesis [GO:0009405]; protein folding [GO:0006457]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	pathogenesis [GO:0009405]; protein folding [GO:0006457]	chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	cell outer membrane [GO:0009279]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1fdba__d1bqxa___1			Proteobacteria	Firmicutes	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1fdia1_d1e32a1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; plasma membrane respiratory chain complex I [GO:0045272]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (NAD+) activity [GO:0008863]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; formate oxidation [GO:0015944]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	formate oxidation [GO:0015944]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	cytosol [GO:0005829]; plasma membrane respiratory chain complex I [GO:0045272]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (NAD+) activity [GO:0008863]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1fdjb__d4bwld1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815]	cytosol [GO:0005829]	fructose-bisphosphate aldolase activity [GO:0004332]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d1fdlh2_d4lbea1__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	voltage-gated potassium channel complex [GO:0008076]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1fdll1_d4otxm1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1fdqb__d3npoa___1	Metazoa	Metazoa	Chordata	Chordata	cell periphery [GO:0071944]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; lipid binding [GO:0008289]; cell proliferation in forebrain [GO:0021846]; epithelial cell proliferation [GO:0050673]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cell proliferation in forebrain [GO:0021846]; epithelial cell proliferation [GO:0050673]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]; triglyceride catabolic process [GO:0019433]		cell-cell junction [GO:0005911]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	extracellular region [GO:0005576]	lipid binding [GO:0008289]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]
d1fdta__d2idza___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]; estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d1fduc__d1zmtc___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]; estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]		estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]	
d1fdvc__d2zk7b___1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]; estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1fdya__d1rv8d___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	fructose-bisphosphate aldolase activity [GO:0004332]; zinc ion binding [GO:0008270]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	fructose 1,6-bisphosphate metabolic process [GO:0030388]; glycolytic process [GO:0006096]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	fructose-bisphosphate aldolase activity [GO:0004332]; zinc ion binding [GO:0008270]
d1fdya__d3s0ca___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d1fdyc__d1euna___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	metabolic process [GO:0008152]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]
d1fe0b__d1yjva1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper ion binding [GO:0005507]; copper-dependent protein binding [GO:0032767]; metallochaperone activity [GO:0016530]; cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]; antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cell [GO:0005623]; cytosol [GO:0005829]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; metallochaperone activity [GO:0016530]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]
d1fe8h1_d3mztc___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1fe8i1_d2ospc2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fe8j1_d2cjvh___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fe8j1_d4am0b2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1fe8l1_d1nakl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1fe8m1_d1tjhl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	structural molecule activity [GO:0005198]
d1fe8m1_d4fg6f2__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	integral component of plasma membrane [GO:0005887]; antiporter activity [GO:0015297]; voltage-gated chloride channel activity [GO:0005247]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	integral component of plasma membrane [GO:0005887]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antiporter activity [GO:0015297]; voltage-gated chloride channel activity [GO:0005247]
d1feac2_d2gvca2__1		Fungi		Ascomycota	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]; cell redox homeostasis [GO:0045454]	endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; monooxygenase activity [GO:0004497]; N,N-dimethylaniline monooxygenase activity [GO:0004499]; NADP binding [GO:0050661]; protein folding in endoplasmic reticulum [GO:0034975]	cell redox homeostasis [GO:0045454]	protein folding in endoplasmic reticulum [GO:0034975]	cell [GO:0005623]; cytoplasm [GO:0005737]	endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]	flavin adenine dinucleotide binding [GO:0050660]; monooxygenase activity [GO:0004497]; N,N-dimethylaniline monooxygenase activity [GO:0004499]; NADP binding [GO:0050661]
d1febb2_d4ovia2__1				Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]; cell redox homeostasis [GO:0045454]	phenylacetone monooxygenase activity [GO:0033776]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]; cytoplasm [GO:0005737]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]	phenylacetone monooxygenase activity [GO:0033776]
d1feea__d2ofhx___1	Metazoa		Chordata	Cyanobacteria	cell [GO:0005623]; cytosol [GO:0005829]; ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper ion binding [GO:0005507]; copper-dependent protein binding [GO:0032767]; metallochaperone activity [GO:0016530]; cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; cadmium ion transmembrane transporter activity [GO:0015086]; metal ion binding [GO:0046872]; zinc ion transmembrane transporter activity [GO:0005385]; zinc transmembrane transporter activity, phosphorylative mechanism [GO:0016463]	cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytosol [GO:0005829]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; metallochaperone activity [GO:0016530]	ATP binding [GO:0005524]; cadmium ion transmembrane transporter activity [GO:0015086]; metal ion binding [GO:0046872]; zinc ion transmembrane transporter activity [GO:0005385]; zinc transmembrane transporter activity, phosphorylative mechanism [GO:0016463]
d1feha2_d2w3sg1__1			Firmicutes	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1fejd__d5ozqa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1fema__d4omwd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; retinol binding [GO:0019841]			extracellular space [GO:0005615]	extracellular region [GO:0005576]	retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	identical protein binding [GO:0042802]; retinol binding [GO:0019841]
d1fesa__d4qotb___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; copper chaperone activity [GO:0016531]; cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]; ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper ion binding [GO:0005507]; copper-dependent protein binding [GO:0032767]; metallochaperone activity [GO:0016530]; cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]	copper chaperone activity [GO:0016531]	ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; metallochaperone activity [GO:0016530]
d1feza__d1swvb___1			Firmicutes	Firmicutes	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	organic phosphonate catabolic process [GO:0019700]	organic phosphonate catabolic process [GO:0019700]			magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]
d1feza__d3r9ka1__1			Firmicutes	Bacteroidetes	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	organic phosphonate catabolic process [GO:0019700]				magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]
d1fezb__d2fi1a1__1			Firmicutes	Firmicutes	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	organic phosphonate catabolic process [GO:0019700]				magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1ff0c__d5b18b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d1ff1a__d2dfsb1__1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]; clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]
d1ff5a2_d4zmtc1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d1ff5b1_d3lnea2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d1ff5b1_d4zmza1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d1ff5b2_d3ppea2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	bicellular tight junction [GO:0005923]; catenin complex [GO:0016342]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; fibrinogen binding [GO:0070051]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; adherens junction organization [GO:0034332]; blood vessel maturation [GO:0001955]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular calcium ion homeostasis [GO:0006874]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of angiogenesis [GO:0045766]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell migration [GO:0030335]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of establishment of cell polarity [GO:2000114]; regulation of protein phosphorylation [GO:0001932]; regulation of vascular permeability [GO:0043114]; transforming growth factor beta receptor signaling pathway [GO:0007179]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; blood vessel maturation [GO:0001955]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular calcium ion homeostasis [GO:0006874]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of angiogenesis [GO:0045766]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell migration [GO:0030335]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of establishment of cell polarity [GO:2000114]; regulation of protein phosphorylation [GO:0001932]; regulation of vascular permeability [GO:0043114]; transforming growth factor beta receptor signaling pathway [GO:0007179]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	bicellular tight junction [GO:0005923]; catenin complex [GO:0016342]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	beta-catenin binding [GO:0008013]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; fibrinogen binding [GO:0070051]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; vascular endothelial growth factor receptor 2 binding [GO:0043184]
d1ffca__d1cuha___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	cutinase activity [GO:0050525]	cutinase activity [GO:0050525]
d1ffda__d3d2cl___1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cutinase activity [GO:0050525]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d1ffea__d5dnua___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; cutinase activity [GO:0050525]				extracellular region [GO:0005576]		cutinase activity [GO:0050525]	
d1fffc__d3nu3b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ffid__d5ozha___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1ffkf__d2j03q1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1ffkm__d1yijp1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1ffko__d2hgqv1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1ffkv__d1njiz___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1ffnd1_d2z4qa1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ffnd1_d4z77b1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ffne1_d1ahwb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ffoa1_d1ahwd2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ffob1_d1nc4b1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1ffod1_d5gs1g2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1ffpa2_d2q7yc2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ffpd2_d4pjda1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ffpe1_d4pjxf1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ffqa1_d2cxga1__1			Proteobacteria	Firmicutes	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1ffqa1_d4lq1d1__1			Proteobacteria	Proteobacteria	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]		cytosol [GO:0005829]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1ffra3_d2anfa2__1			Proteobacteria		chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]				chitinase activity [GO:0004568]; chitin binding [GO:0008061]	
d1ffsa__d4le0a___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	DNA binding [GO:0003677]
d1fftb1_d1zdsa1__1			Proteobacteria	Proteobacteria	cytochrome o ubiquinol oxidase complex [GO:0009319]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytochrome bo3 ubiquinol oxidase activity [GO:0009486]; cytochrome o ubiquinol oxidase activity [GO:0008827]; electron transfer activity [GO:0009055]; oxidoreduction-driven active transmembrane transporter activity [GO:0015453]; proton transmembrane transporter activity [GO:0015078]; aerobic electron transport chain [GO:0019646]; aerobic respiration [GO:0009060]; electron transport coupled proton transport [GO:0015990]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	aerobic electron transport chain [GO:0019646]; aerobic respiration [GO:0009060]; electron transport coupled proton transport [GO:0015990]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cytochrome o ubiquinol oxidase complex [GO:0009319]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	cytochrome bo3 ubiquinol oxidase activity [GO:0009486]; cytochrome o ubiquinol oxidase activity [GO:0008827]; electron transfer activity [GO:0009055]; oxidoreduction-driven active transmembrane transporter activity [GO:0015453]; proton transmembrane transporter activity [GO:0015078]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1ffua2_d2mh7a1__1		Viridiplantae	Proteobacteria	Chlorophyta	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	chloroplast [GO:0009507]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]				chloroplast [GO:0009507]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1ffub1_d3amza5__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1ffub1_d3nvvc1__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1ffuc1_d3sr6k2__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1ffud1_d1vdvb1__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1ffue1_d1sija3__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1ffue1_d1zxie1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1ffuf1_d1qj2i4__1			Proteobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	
d1ffva1_d1hlra6__1			Proteobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	
d1ffvc1_d1n61f1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1ffvc1_d3etrm2__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1ffvf1_d1jroc3__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1ffwc__d3rvna1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]	cytosol [GO:0005829]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d1ffya1_d1gaxa5__1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; isoleucyl-tRNA aminoacylation [GO:0006428]	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; valine-tRNA ligase activity [GO:0004832]; valyl-tRNA aminoacylation [GO:0006438]	isoleucyl-tRNA aminoacylation [GO:0006428]	valyl-tRNA aminoacylation [GO:0006438]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; valine-tRNA ligase activity [GO:0004832]
d1fg2a1_d3cfke2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fg2a1_d5mi0c1__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	apical part of cell [GO:0045177]; bicellular tight junction [GO:0005923]; host cell membrane [GO:0033644]; host extracellular space [GO:0043655]; protein-containing complex [GO:0032991]; rhoptry [GO:0020008]; rhoptry lumen [GO:0034591]; heparin binding [GO:0008201]; host cell surface receptor binding [GO:0046789]; entry into host [GO:0044409]; entry into host cell [GO:0030260]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	entry into host [GO:0044409]; entry into host cell [GO:0030260]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; bicellular tight junction [GO:0005923]; host cell membrane [GO:0033644]; host extracellular space [GO:0043655]; protein-containing complex [GO:0032991]; rhoptry [GO:0020008]; rhoptry lumen [GO:0034591]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	heparin binding [GO:0008201]; host cell surface receptor binding [GO:0046789]
d1fg2b__d1fg2j1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1fg2d1_d4h0ga1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1fg2e__d1mlcb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1fg2h__d5xmmb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1fg2j1_d2fjfg1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1fg8c__d1s6gb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d1fg9c1_d5kbnc___1	Metazoa		Chordata	Proteobacteria	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interferon-gamma receptor activity [GO:0004906]; astrocyte activation [GO:0048143]; cytokine-mediated signaling pathway [GO:0019221]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of gene expression [GO:0010628]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; response to virus [GO:0009615]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; inorganic anion transmembrane transporter activity [GO:0015103]	astrocyte activation [GO:0048143]; cytokine-mediated signaling pathway [GO:0019221]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of gene expression [GO:0010628]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; response to virus [GO:0009615]; signal transduction [GO:0007165]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interferon-gamma receptor activity [GO:0004906]	inorganic anion transmembrane transporter activity [GO:0015103]
d1fgcc__d5p5ua___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1fgha1_d2b3xa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; intestinal absorption [GO:0050892]; post-embryonic development [GO:0009791]; regulation of translation [GO:0006417]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099]	citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; intestinal absorption [GO:0050892]; post-embryonic development [GO:0009791]; regulation of translation [GO:0006417]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d1fgma1_d1no3a1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]; oxylipin biosynthetic process [GO:0031408]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; oxylipin biosynthetic process [GO:0031408]	oxylipin biosynthetic process [GO:0031408]	oxylipin biosynthetic process [GO:0031408]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d1fgua1_d1pa6b___1	Metazoa		Chordata	Ciliophora	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]; damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	telomere capping [GO:0016233]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1fgub1_d3cw2c1__1	Metazoa		Chordata	Crenarchaeota	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]; damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]	cytosol [GO:0005829]	damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1fh2a__d4pwgb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1fh5l1_d3t77a1__1		Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]
d1fh5l1_d4r8wl___1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d1fh5l2_d3zlqc1__1		Metazoa		Chordata		dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]		aspartic-type endopeptidase activity [GO:0004190]
d1fh8a__d4toqa___1		Viridiplantae	Actinobacteria	Streptophyta	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	amyloplast [GO:0009501]; calcium ion binding [GO:0005509]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]; seed germination [GO:0009845]; seedling development [GO:0090351]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]; seed germination [GO:0009845]; seedling development [GO:0090351]		amyloplast [GO:0009501]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]	calcium ion binding [GO:0005509]; chitinase activity [GO:0004568]
d1fhea1_d1gtua1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	glutathione transferase activity [GO:0004364]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d1fhfc__d1ly8b___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1fhga__d2f5bh1__1	Metazoa		Chordata		calmodulin binding [GO:0005516]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	calmodulin binding [GO:0005516]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1fhjb__d1jp8a___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1fhjc__d3lb4a___1	Metazoa	Metazoa	Chordata	Annelida	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d1fhna__d2wqac___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1fhsa__d5i6vb1__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]; abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]
d1fhwa__d2yrya1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; establishment of epithelial cell polarity [GO:0090162]; Golgi vesicle transport [GO:0048193]; positive regulation of cell adhesion [GO:0045785]; regulation of ARF protein signal transduction [GO:0032012]		establishment of epithelial cell polarity [GO:0090162]; Golgi vesicle transport [GO:0048193]; positive regulation of cell adhesion [GO:0045785]; regulation of ARF protein signal transduction [GO:0032012]		adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle [GO:0001726]		ARF guanyl-nucleotide exchange factor activity [GO:0005086]; guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]	
d1fi2a__d2paka1__1	Viridiplantae		Streptophyta	Firmicutes	apoplast [GO:0048046]; cell wall [GO:0005618]; superoxide dismutase complex [GO:1902693]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; nutrient reservoir activity [GO:0045735]; oxalate oxidase activity [GO:0050162]; superoxide dismutase activity [GO:0004784]; cell wall organization [GO:0071555]; oxidation-reduction process [GO:0055114]; protein homooligomerization [GO:0051260]; removal of superoxide radicals [GO:0019430]	isomerase activity [GO:0016853]	cell wall organization [GO:0071555]; oxidation-reduction process [GO:0055114]; protein homooligomerization [GO:0051260]; removal of superoxide radicals [GO:0019430]		apoplast [GO:0048046]; cell wall [GO:0005618]; superoxide dismutase complex [GO:1902693]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; nutrient reservoir activity [GO:0045735]; oxalate oxidase activity [GO:0050162]; superoxide dismutase activity [GO:0004784]	isomerase activity [GO:0016853]
d1fi9a__d1aofa1__1	Metazoa		Chordata	Proteobacteria	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]		cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1fi9a__d1nmia___1	Metazoa	Fungi	Chordata	Ascomycota	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1fiba__d1z3ua1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]
d1fica__d2j0gf___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1fiea3_d1ggta3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1fieb3_d1ggtb2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1figh1_d1lhza1__1		Metazoa		Chordata								
d1figl1_d1fp5a1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1figl1_d3idia1__1												
d1fila__d1acfa___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleus [GO:0005634]; actin binding [GO:0003779]; actin monomer binding [GO:0003785]; adenyl-nucleotide exchange factor activity [GO:0000774]; cadherin binding [GO:0045296]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; proline-rich region binding [GO:0070064]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; modification of postsynaptic actin cytoskeleton [GO:0098885]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of ATPase activity [GO:0032781]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ruffle assembly [GO:1900029]; protein stabilization [GO:0050821]; regulation of actin filament polymerization [GO:0030833]; regulation of transcription by RNA polymerase II [GO:0006357]; synapse maturation [GO:0060074]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]	actin cytoskeleton organization [GO:0030036]; modification of postsynaptic actin cytoskeleton [GO:0098885]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of ATPase activity [GO:0032781]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ruffle assembly [GO:1900029]; protein stabilization [GO:0050821]; regulation of actin filament polymerization [GO:0030833]; regulation of transcription by RNA polymerase II [GO:0006357]; synapse maturation [GO:0060074]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]		blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; actin monomer binding [GO:0003785]; adenyl-nucleotide exchange factor activity [GO:0000774]; cadherin binding [GO:0045296]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; proline-rich region binding [GO:0070064]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]	actin binding [GO:0003779]
d1fiqa2_d1oqra___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1fiqb1_d1n63f1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1fiqb1_d2w3rc4__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1fiqb2_d2w3se3__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1fj0b__d1etpa1__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	photosynthesis [GO:0015979]			periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1fj1b1_d2z8wc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fj1b2_d3o2dl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1fj1c2_d1e4xh1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fj1d1_d3b2uc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d1fj1d1_d5sx4l2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d1fj3a__d4dd8d___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	alpha9-beta1 integrin-ADAM8 complex [GO:0071133]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dense core granule membrane [GO:0032127]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; phagolysosome [GO:0032010]; plasma membrane [GO:0005886]; podosome [GO:0002102]; specific granule [GO:0042581]; specific granule membrane [GO:0035579]; tertiary granule [GO:0070820]; tertiary granule membrane [GO:0070821]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; protein self-association [GO:0043621]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cellular response to hypoxia [GO:0071456]; extracellular matrix disassembly [GO:0022617]; inflammatory response [GO:0006954]; leukocyte migration involved in inflammatory response [GO:0002523]; lymphocyte chemotaxis [GO:0048247]; negative regulation of neuron apoptotic process [GO:0043524]; neutrophil degranulation [GO:0043312]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell adhesion [GO:0045785]; positive regulation of eosinophil migration [GO:2000418]; positive regulation of fibronectin-dependent thymocyte migration [GO:2000415]; positive regulation of innate immune response [GO:0045089]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein processing [GO:0010954]; positive regulation of protein secretion [GO:0050714]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; regulation of cell-cell adhesion [GO:0022407]		angiogenesis [GO:0001525]; cell-cell adhesion [GO:0098609]; cell morphogenesis [GO:0000902]; cellular response to hypoxia [GO:0071456]; extracellular matrix disassembly [GO:0022617]; inflammatory response [GO:0006954]; leukocyte migration involved in inflammatory response [GO:0002523]; lymphocyte chemotaxis [GO:0048247]; negative regulation of neuron apoptotic process [GO:0043524]; neutrophil degranulation [GO:0043312]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell adhesion [GO:0045785]; positive regulation of eosinophil migration [GO:2000418]; positive regulation of fibronectin-dependent thymocyte migration [GO:2000415]; positive regulation of innate immune response [GO:0045089]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein processing [GO:0010954]; positive regulation of protein secretion [GO:0050714]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; regulation of cell-cell adhesion [GO:0022407]	extracellular region [GO:0005576]	alpha9-beta1 integrin-ADAM8 complex [GO:0071133]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dense core granule membrane [GO:0032127]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; phagolysosome [GO:0032010]; plasma membrane [GO:0005886]; podosome [GO:0002102]; specific granule [GO:0042581]; specific granule membrane [GO:0035579]; tertiary granule [GO:0070820]; tertiary granule membrane [GO:0070821]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; protein self-association [GO:0043621]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1fj4a2_d2cf2j1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1fj4b1_d1afwa2__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	mitochondrial intermembrane space [GO:0005758]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acetyl-CoA C-acyltransferase activity [GO:0003988]; mRNA binding [GO:0003729]; fatty acid beta-oxidation [GO:0006635]; phenylacetate catabolic process [GO:0010124]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid beta-oxidation [GO:0006635]; phenylacetate catabolic process [GO:0010124]	cytosol [GO:0005829]	mitochondrial intermembrane space [GO:0005758]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acyltransferase activity [GO:0003988]; mRNA binding [GO:0003729]
d1fj4c1_d5byvk2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1fj4d1_d1w0ia1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	mitochondrion [GO:0005739]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; thylakoid membrane organization [GO:0010027]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; thylakoid membrane organization [GO:0010027]	cytosol [GO:0005829]	mitochondrion [GO:0005739]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1fj7a__d5lslb___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; ribonucleoprotein complex [GO:1990904]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]	nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]; RNA binding [GO:0003723]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; ribonucleoprotein complex [GO:1990904]	nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]	RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]	RNA binding [GO:0003723]
d1fj8a2_d1ulqb2__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1fj8c2_d1oxha2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d1fj8d2_d4jgaa2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1fjda__d2dg9a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; preribosome [GO:0030684]; spindle [GO:0005819]; bent DNA binding [GO:0003681]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	rRNA processing [GO:0006364]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; preribosome [GO:0030684]; spindle [GO:0005819]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	bent DNA binding [GO:0003681]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]
d1fjgd__d2gybd1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1fjge1_d2c39b1__1			Deinococcus-Thermus	Crenarchaeota	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	translation [GO:0006412]	rRNA catabolic process [GO:0016075]	ribosome [GO:0005840]	cytoplasmic exosome (RNase complex) [GO:0000177]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	3'-5'-exoribonuclease activity [GO:0000175]
d1fjgi__d2o3za1__1			Deinococcus-Thermus	Aquificae	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	translation [GO:0006412]	lipid A biosynthetic process [GO:0009245]	ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d1fjqa__d1xura___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]		bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1fjsa__d4wy3a___1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1fjva__d5t9ia___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1fjwa__d1keia___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1fk2a__d1bfaa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lipid binding [GO:0008289]; lipid transport [GO:0006869]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	lipid transport [GO:0006869]			extracellular region [GO:0005576]	lipid binding [GO:0008289]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1fk3a__d1lipa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid transport [GO:0006869]	lipid transport [GO:0006869]			lipid binding [GO:0008289]	lipid binding [GO:0008289]
d1fk7a__d3gsha___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid transport [GO:0006869]	lipid transport [GO:0006869]			lipid binding [GO:0008289]	lipid binding [GO:0008289]
d1fkca__d4hmma___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d1fkib__d2kgja1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	integral component of external side of plasma membrane [GO:0071575]; identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	chaperone-mediated protein folding [GO:0061077]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	integral component of external side of plasma membrane [GO:0071575]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1fkka__d4dz2b1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018]; activin binding [GO:0048185]; calcium channel inhibitor activity [GO:0019855]; drug binding [GO:0008144]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein homodimerization activity [GO:0042803]; SMAD binding [GO:0046332]; amyloid fibril formation [GO:1990000]; chaperone-mediated protein folding [GO:0061077]; cytokine-mediated signaling pathway [GO:0019221]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; muscle contraction [GO:0006936]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of release of sequestered calcium ion into cytosol [GO:0051280]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; release of sequestered calcium ion into cytosol [GO:0051209]; response to caffeine [GO:0031000]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; T cell proliferation [GO:0042098]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	metal ion binding [GO:0046872]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	amyloid fibril formation [GO:1990000]; chaperone-mediated protein folding [GO:0061077]; cytokine-mediated signaling pathway [GO:0019221]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; muscle contraction [GO:0006936]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of release of sequestered calcium ion into cytosol [GO:0051280]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; release of sequestered calcium ion into cytosol [GO:0051209]; response to caffeine [GO:0031000]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; T cell proliferation [GO:0042098]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018]		activin binding [GO:0048185]; calcium channel inhibitor activity [GO:0019855]; drug binding [GO:0008144]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein homodimerization activity [GO:0042803]; SMAD binding [GO:0046332]	metal ion binding [GO:0046872]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1fknb__d1t7ja___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1fkra__d4ipxa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]
d1fksa__d4itza___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]		cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]		activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1fl3a1_d1u8ib1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fl3a1_d2vdll2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fl3b1_d3sgka2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	IgG binding [GO:0019864]
d1fl3b2_d5j89d1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fl3h2_d2rgsb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fl3l1_d2mpal2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fl3l2_d4bjla1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fl5a1_d5adpl1__1												
d1fl5a2_d4depe3__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]		cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]		interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]
d1fl5b1_d2r2hb1__1		Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]
d1fl5b1_d3zkml2__1		Metazoa		Chordata		dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]		aspartic-type endopeptidase activity [GO:0004190]
d1fl5l1_d5hyec2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fl5l2_d2dqtl1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fl6a1_d1dbah1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fl6a1_d5u6qd2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1fl6b1_d2iwgd2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fl6b1_d2wbwb___1		Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1fl6b2_d1kpva1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1fl6h2_d3tlrd1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1fl6l2_d5u4rb1__1												
d1flce1_d2wr7b1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; sialate O-acetylesterase activity [GO:0001681]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]; sialate O-acetylesterase activity [GO:0001681]	host cell surface receptor binding [GO:0046789]
d1flee__d3snba___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1flgb__d1g72c___1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; alcohol dehydrogenase (acceptor) activity [GO:0018468]; calcium ion binding [GO:0005509]; ethanol:cytochrome c oxidoreductase activity [GO:0052935]; ethanol oxidation [GO:0006069]	plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol oxidation [GO:0015946]	ethanol oxidation [GO:0006069]	methanol oxidation [GO:0015946]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	plasma membrane [GO:0005886]	alcohol dehydrogenase (acceptor) activity [GO:0018468]; calcium ion binding [GO:0005509]; ethanol:cytochrome c oxidoreductase activity [GO:0052935]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]
d1flha__d5p47a___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; multivesicular body lumen [GO:0097486]; aspartic-type endopeptidase activity [GO:0004190]; cellular protein metabolic process [GO:0044267]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	aspartic-type endopeptidase activity [GO:0004190]	cellular protein metabolic process [GO:0044267]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		extracellular exosome [GO:0070062]; multivesicular body lumen [GO:0097486]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1flka1_d1d0af1__1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome [GO:0005768]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; protein deubiquitination [GO:0016579]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; protein deubiquitination [GO:0016579]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; toll-like receptor signaling pathway [GO:0002224]; Toll signaling pathway [GO:0008063]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	CD40 receptor complex [GO:0035631]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome [GO:0005768]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1flka1_d5wzzc___1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome [GO:0005768]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; protein deubiquitination [GO:0016579]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	beta-catenin destruction complex [GO:0030877]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling adaptor activity [GO:0035591]; SMAD binding [GO:0046332]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular protein-containing complex assembly [GO:0034622]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of Wnt signaling pathway [GO:0030111]; Wnt signaling pathway [GO:0016055]	apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; protein deubiquitination [GO:0016579]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; toll-like receptor signaling pathway [GO:0002224]; Toll signaling pathway [GO:0008063]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular protein-containing complex assembly [GO:0034622]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of Wnt signaling pathway [GO:0030111]; Wnt signaling pathway [GO:0016055]	CD40 receptor complex [GO:0035631]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome [GO:0005768]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	beta-catenin destruction complex [GO:0030877]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; I-SMAD binding [GO:0070411]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling adaptor activity [GO:0035591]; SMAD binding [GO:0046332]; ubiquitin protein ligase binding [GO:0031625]
d1flkb1_d1ca9f1__1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome [GO:0005768]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; protein deubiquitination [GO:0016579]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; protein deubiquitination [GO:0016579]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; toll-like receptor signaling pathway [GO:0002224]; Toll signaling pathway [GO:0008063]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	CD40 receptor complex [GO:0035631]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome [GO:0005768]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1flkb1_d4c9zb___1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome [GO:0005768]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; protein deubiquitination [GO:0016579]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	beta-catenin destruction complex [GO:0030877]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; anatomical structure morphogenesis [GO:0009653]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; cell cycle [GO:0007049]; cellular protein metabolic process [GO:0044267]; negative regulation of netrin-activated signaling pathway [GO:1902842]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]	apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; protein deubiquitination [GO:0016579]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; toll-like receptor signaling pathway [GO:0002224]; Toll signaling pathway [GO:0008063]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	anatomical structure morphogenesis [GO:0009653]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; cell cycle [GO:0007049]; cellular protein metabolic process [GO:0044267]; negative regulation of netrin-activated signaling pathway [GO:1902842]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]	CD40 receptor complex [GO:0035631]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome [GO:0005768]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	beta-catenin destruction complex [GO:0030877]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1flla1_d5wzza___1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; varicosity [GO:0043196]; antigen binding [GO:0003823]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; cellular calcium ion homeostasis [GO:0006874]; cellular response to erythropoietin [GO:0036018]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; inflammatory response [GO:0006954]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein kinase B signaling [GO:0043491]; protein-containing complex assembly [GO:0065003]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; response to cobalamin [GO:0033590]; response to interferon-gamma [GO:0034341]; response to peptide [GO:1901652]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	beta-catenin destruction complex [GO:0030877]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling adaptor activity [GO:0035591]; SMAD binding [GO:0046332]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular protein-containing complex assembly [GO:0034622]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of Wnt signaling pathway [GO:0030111]; Wnt signaling pathway [GO:0016055]	B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; cellular calcium ion homeostasis [GO:0006874]; cellular response to erythropoietin [GO:0036018]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; inflammatory response [GO:0006954]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein-containing complex assembly [GO:0065003]; protein kinase B signaling [GO:0043491]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; response to cobalamin [GO:0033590]; response to interferon-gamma [GO:0034341]; response to peptide [GO:1901652]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular protein-containing complex assembly [GO:0034622]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of Wnt signaling pathway [GO:0030111]; Wnt signaling pathway [GO:0016055]	CD40 receptor complex [GO:0035631]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; varicosity [GO:0043196]	beta-catenin destruction complex [GO:0030877]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	antigen binding [GO:0003823]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]	armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; I-SMAD binding [GO:0070411]; molecular adaptor activity [GO:0060090]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling adaptor activity [GO:0035591]; SMAD binding [GO:0046332]; ubiquitin protein ligase binding [GO:0031625]
d1flna__d1ofva___1			Firmicutes	Cyanobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1flna__d3uxha___1		Metazoa	Firmicutes	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1flpa__d5ee4f___1	Metazoa	Metazoa	Mollusca	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen transport [GO:0015671]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxygen transport [GO:0015671]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1flrl1_d5vpgc1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cysteine-type peptidase activity [GO:0008234]; metal ion binding [GO:0046872]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cysteine-type peptidase activity [GO:0008234]; metal ion binding [GO:0046872]
d1flrl2_d2qr0n1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1flza__d2zhxg___1			Proteobacteria	Actinobacteria	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d1fm0d__d2pkoa___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; molybdopterin synthase activity [GO:0030366]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein homodimerization activity [GO:0042803]; protein tag [GO:0031386]; sulfur carrier activity [GO:0097163]; cell budding [GO:0007114]; cellular response to oxidative stress [GO:0034599]; invasive growth in response to glucose limitation [GO:0001403]; protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble position uridine thiolation [GO:0002143]; tRNA wobble uridine modification [GO:0002098]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cell budding [GO:0007114]; cellular response to oxidative stress [GO:0034599]; invasive growth in response to glucose limitation [GO:0001403]; protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble position uridine thiolation [GO:0002143]; tRNA wobble uridine modification [GO:0002098]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	molybdopterin synthase activity [GO:0030366]	protein homodimerization activity [GO:0042803]; protein tag [GO:0031386]; sulfur carrier activity [GO:0097163]
d1fm1a__d1jaqa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1fm4a__d5mmua___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	cytoplasm [GO:0005737]		abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d1fm8a__d4doia___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chalcone isomerase activity [GO:0045430]; flavonoid biosynthetic process [GO:0009813]	chloroplast [GO:0009507]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extrinsic component of endoplasmic reticulum membrane [GO:0042406]; nucleus [GO:0005634]; plant-type vacuole membrane [GO:0009705]; chalcone isomerase activity [GO:0045430]; flavonoid biosynthetic process [GO:0009813]; response to auxin [GO:0009733]; response to karrikin [GO:0080167]; response to UV [GO:0009411]; response to UV-B [GO:0010224]	flavonoid biosynthetic process [GO:0009813]	flavonoid biosynthetic process [GO:0009813]; response to auxin [GO:0009733]; response to karrikin [GO:0080167]; response to UV [GO:0009411]; response to UV-B [GO:0010224]		chloroplast [GO:0009507]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extrinsic component of endoplasmic reticulum membrane [GO:0042406]; nucleus [GO:0005634]; plant-type vacuole membrane [GO:0009705]	chalcone isomerase activity [GO:0045430]	chalcone isomerase activity [GO:0045430]
d1fmcb__d1udaa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; cholate 7-alpha-dehydrogenase activity [GO:0008709]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; bile acid catabolic process [GO:0030573]; lipid catabolic process [GO:0016042]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]; carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	bile acid catabolic process [GO:0030573]; lipid catabolic process [GO:0016042]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cholate 7-alpha-dehydrogenase activity [GO:0008709]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]
d1fmfa__d1bmtb2__1			Firmicutes	Proteobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]; anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cobalamin binding [GO:0031419]; methionine synthase activity [GO:0008705]; protein methyltransferase activity [GO:0008276]; zinc ion binding [GO:0008270]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]	anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]	homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]	cobalamin binding [GO:0031419]; methionine synthase activity [GO:0008705]; protein methyltransferase activity [GO:0008276]; zinc ion binding [GO:0008270]
d1fmga__d3qzqc___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	cysteine-type endopeptidase activity [GO:0004197]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]
d1fmms__d3crga1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mesonephric epithelium development [GO:0072163]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of transcription by RNA polymerase II [GO:0045944]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mesonephric epithelium development [GO:0072163]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of transcription by RNA polymerase II [GO:0045944]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1fmms__d7i1ba___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mesonephric epithelium development [GO:0072163]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of transcription by RNA polymerase II [GO:0045944]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mesonephric epithelium development [GO:0072163]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of transcription by RNA polymerase II [GO:0045944]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d1fmtb1_d4r8va2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; methionyl-tRNA formyltransferase activity [GO:0004479]; charged-tRNA amino acid modification [GO:0019988]; conversion of methionyl-tRNA to N-formyl-methionyl-tRNA [GO:0071951]	cytoplasm [GO:0005737]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydrolase activity [GO:0016787]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; embryonic viscerocranium morphogenesis [GO:0048703]; gastrulation [GO:0007369]; heart development [GO:0007507]; neural crest cell migration [GO:0001755]; neuromast deposition [GO:0048885]; one-carbon metabolic process [GO:0006730]	charged-tRNA amino acid modification [GO:0019988]; conversion of methionyl-tRNA to N-formyl-methionyl-tRNA [GO:0071951]	10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; embryonic viscerocranium morphogenesis [GO:0048703]; gastrulation [GO:0007369]; heart development [GO:0007507]; neural crest cell migration [GO:0001755]; neuromast deposition [GO:0048885]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	methionyl-tRNA formyltransferase activity [GO:0004479]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydrolase activity [GO:0016787]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]
d1fn0a__d2vu9a2__1	Viridiplantae		Streptophyta	Firmicutes	serine-type endopeptidase inhibitor activity [GO:0004867]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	serine-type endopeptidase inhibitor activity [GO:0004867]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1fn3b__d1lial___1	Metazoa		Chordata	Rhodophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1fn4c1_d1fyte1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fn4c1_d1gpom2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fn4c2_d5wk2l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fn4d1_d3c5sa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fn4d2_d1lp9m1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1fn9a__d1jmug___1					viral outer capsid [GO:0039624]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral life cycle [GO:0019058]	host cell endoplasmic reticulum [GO:0044165]; host cell mitochondrion [GO:0033650]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; viral capsid [GO:0019028]; viral outer capsid [GO:0039624]; host cell surface binding [GO:0046812]; pathogenesis [GO:0009405]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]	regulation of translation [GO:0006417]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral life cycle [GO:0019058]	pathogenesis [GO:0009405]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]	viral outer capsid [GO:0039624]	host cell endoplasmic reticulum [GO:0044165]; host cell mitochondrion [GO:0033650]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; viral capsid [GO:0019028]; viral outer capsid [GO:0039624]	metal ion binding [GO:0046872]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell surface binding [GO:0046812]
d1fnaa__d2b5ib2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]; interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]	interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]
d1fnba1_d4f7db1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	photosynthesis [GO:0015979]		chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]		ferredoxin-NADP+ reductase activity [GO:0004324]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1fnba2_d4yafa3__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	photosynthesis [GO:0015979]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1fnca2_d5vw4a2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	photosynthesis [GO:0015979]		chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	chloroplast [GO:0009507]	ferredoxin-NADP+ reductase activity [GO:0004324]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1fnda2_d1b2ra2__1	Viridiplantae		Streptophyta	Cyanobacteria	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d1fneb1_d4onha1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1fnec1_d4eigb1__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d1fnec2_d1xz0a2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1fnec2_d3ma7a1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1fned1_d4pjgf2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1fnfa4_d2dm4a1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	cell [GO:0005623]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; multivesicular body [GO:0005771]; multivesicular body membrane [GO:0032585]; nuclear envelope lumen [GO:0005641]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; ADP-ribosylation factor binding [GO:0030306]; amyloid-beta binding [GO:0001540]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor activity [GO:0005041]; transmembrane signaling receptor activity [GO:0004888]; adaptive thermogenesis [GO:1990845]; cellular protein metabolic process [GO:0044267]; diet induced thermogenesis [GO:0002024]; insulin receptor recycling [GO:0038020]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of neurofibrillary tangle assembly [GO:1902997]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of triglyceride catabolic process [GO:0010897]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of choline O-acetyltransferase activity [GO:1902771]; positive regulation of early endosome to recycling endosome transport [GO:1902955]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of glial cell-derived neurotrophic factor secretion [GO:1900168]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to early endosome [GO:1902966]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to Golgi apparatus [GO:0034067]; protein maturation [GO:0051604]; protein retention in Golgi apparatus [GO:0045053]; protein targeting [GO:0006605]; protein targeting to lysosome [GO:0006622]; receptor-mediated endocytosis [GO:0006898]; regulation of smooth muscle cell migration [GO:0014910]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	adaptive thermogenesis [GO:1990845]; cellular protein metabolic process [GO:0044267]; diet induced thermogenesis [GO:0002024]; insulin receptor recycling [GO:0038020]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of neurofibrillary tangle assembly [GO:1902997]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of triglyceride catabolic process [GO:0010897]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of choline O-acetyltransferase activity [GO:1902771]; positive regulation of early endosome to recycling endosome transport [GO:1902955]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of glial cell-derived neurotrophic factor secretion [GO:1900168]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to early endosome [GO:1902966]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to Golgi apparatus [GO:0034067]; protein maturation [GO:0051604]; protein retention in Golgi apparatus [GO:0045053]; protein targeting [GO:0006605]; protein targeting to lysosome [GO:0006622]; receptor-mediated endocytosis [GO:0006898]; regulation of smooth muscle cell migration [GO:0014910]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	cell [GO:0005623]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; multivesicular body [GO:0005771]; multivesicular body membrane [GO:0032585]; nuclear envelope lumen [GO:0005641]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]	ADP-ribosylation factor binding [GO:0030306]; amyloid-beta binding [GO:0001540]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor activity [GO:0005041]; transmembrane signaling receptor activity [GO:0004888]
d1fnga1_d1wcba2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]			
d1fngd1_d5a16f2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]			
d1fnha1_d2yrza1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	cell junction [GO:0030054]; cell leading edge [GO:0031252]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; hemidesmosome [GO:0030056]; integrin complex [GO:0008305]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; G protein-coupled receptor binding [GO:0001664]; integrin binding [GO:0005178]; amelogenesis [GO:0097186]; autophagy [GO:0006914]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell motility [GO:0048870]; cell-matrix adhesion [GO:0007160]; digestive tract development [GO:0048565]; extracellular matrix organization [GO:0030198]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; mesodermal cell differentiation [GO:0048333]; nail development [GO:0035878]; renal system development [GO:0072001]; response to wounding [GO:0009611]; skin development [GO:0043588]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	amelogenesis [GO:0097186]; autophagy [GO:0006914]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell motility [GO:0048870]; digestive tract development [GO:0048565]; extracellular matrix organization [GO:0030198]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; mesodermal cell differentiation [GO:0048333]; nail development [GO:0035878]; renal system development [GO:0072001]; response to wounding [GO:0009611]; skin development [GO:0043588]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	cell junction [GO:0030054]; cell leading edge [GO:0031252]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; hemidesmosome [GO:0030056]; integrin complex [GO:0008305]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]	G protein-coupled receptor binding [GO:0001664]; integrin binding [GO:0005178]
d1fnla1_d3mlvl2__1	Metazoa		Chordata		anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; IgG binding [GO:0019864]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	immune response [GO:0006955]; neutrophil degranulation [GO:0043312]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	IgG binding [GO:0019864]	structural molecule activity [GO:0005198]
d1fnla2_d1zhba1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; IgG binding [GO:0019864]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	immune response [GO:0006955]; neutrophil degranulation [GO:0043312]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	IgG binding [GO:0019864]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1fnla2_d3qp3c___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; IgG binding [GO:0019864]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	immune response [GO:0006955]; neutrophil degranulation [GO:0043312]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	IgG binding [GO:0019864]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1fnma1_d1ob5c1__1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	translational elongation [GO:0006414]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1fnsl2_d2w0ka1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fnua1_d1bcpf___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1fnuc2_d5d3db2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1fnud2_d3ea6a2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]
d1fnvb2_d2aq3d2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]	extracellular region [GO:0005576]	T cell receptor complex [GO:0042101]	toxin activity [GO:0090729]	
d1fnwb2_d1aw7b2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1fnwb2_d4rcob2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1fnwd2_d3tssa2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1fnwg1_d1lttd___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]		killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1fnxh1_d2hgna___1	Metazoa	Metazoa	Chordata	Chordata	ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; cell differentiation [GO:0030154]; nervous system development [GO:0007399]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; TBP-class protein binding [GO:0017025]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-12-mediated signaling pathway [GO:0035722]; mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	cell differentiation [GO:0030154]; nervous system development [GO:0007399]	fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-12-mediated signaling pathway [GO:0035722]; mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	ribonucleoprotein complex [GO:1990904]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	mRNA 3'-UTR AU-rich region binding [GO:0035925]	RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; TBP-class protein binding [GO:0017025]
d1fnxh2_d2myfa1__1	Metazoa		Chordata	Apicomplexa	ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; cell differentiation [GO:0030154]; nervous system development [GO:0007399]	nuclear speck [GO:0016607]; nucleus [GO:0005634]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; mRNA cis splicing, via spliceosome [GO:0045292]; protein folding [GO:0006457]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	cell differentiation [GO:0030154]; nervous system development [GO:0007399]	mRNA cis splicing, via spliceosome [GO:0045292]; protein folding [GO:0006457]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	ribonucleoprotein complex [GO:1990904]	nuclear speck [GO:0016607]; nucleus [GO:0005634]	mRNA 3'-UTR AU-rich region binding [GO:0035925]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]
d1fo0a__d1mq8a2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]
d1fo0h1_d5e5ud1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; toxin transport [GO:1901998]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; toxin transport [GO:1901998]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]
d1fo4a3_d1ffve1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1fo4a4_d3rcak2__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	
d1fo4a6_d2bvgc1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]
d1fo4b1_d1ffva1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1fo4b4_d1n60f1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1fo4b4_d3nvzb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1fo5a__d4hi7b1__1		Metazoa	Euryarchaeota	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]; cytoplasm [GO:0005737]		electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	
d1fo6b__d1uf5a___1			Proteobacteria	Proteobacteria	N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]; nitrogen compound metabolic process [GO:0006807]	N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]	N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]
d1fo7a__d4h88a___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	anchored component of membrane [GO:0031225]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of catalytic activity [GO:0043086]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization [GO:0032880]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to oxidative stress [GO:0006979]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of catalytic activity [GO:0043086]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization [GO:0032880]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to oxidative stress [GO:0006979]	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]	anchored component of membrane [GO:0031225]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d1foca__d2zxya___1			Deinococcus-Thermus	Aquificae	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]					electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1focb__d1sqxd1__1		Metazoa	Deinococcus-Thermus	Chordata	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1fod3__d1pgl21__1					icosahedral viral capsid [GO:0019030]; structural molecule activity [GO:0005198]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]		transport of virus in host, cell to cell [GO:0046740]	icosahedral viral capsid [GO:0019030]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1foha3_d1hyua4__1	Fungi		Basidiomycota	Proteobacteria	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]; phenol-containing compound catabolic process [GO:0019336]	cell [GO:0005623]; alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	phenol-containing compound catabolic process [GO:0019336]	cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]		cell [GO:0005623]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]	alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]
d1fohc3_d3ie3a1__1	Fungi	Metazoa	Basidiomycota	Chordata	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]; phenol-containing compound catabolic process [GO:0019336]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	phenol-containing compound catabolic process [GO:0019336]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1fohc3_d4xrdb___1	Fungi		Basidiomycota	Proteobacteria	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]; phenol-containing compound catabolic process [GO:0019336]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	phenol-containing compound catabolic process [GO:0019336]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cytosol [GO:0005829]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]	thioredoxin peroxidase activity [GO:0008379]
d1foka1_d4co8a1__1		Metazoa	Firmicutes	Chordata	DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; cell differentiation [GO:0030154]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	DNA restriction-modification system [GO:0009307]	cell differentiation [GO:0030154]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]		nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d1foka3_d4a5na___1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]	DNA restriction-modification system [GO:0009307]				DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]
d1forh1_d5iw1f2__1												
d1forh2_d1mnuh1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1forl2_d4r7db2__1		Metazoa		Chordata								
d1fova__d2pn8c1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; deoxyribonucleotide biosynthetic process [GO:0009263]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; deoxyribonucleotide biosynthetic process [GO:0009263]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d1fp1d1_d1kywf1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	isoliquiritigenin 2'-O-methyltransferase activity [GO:0033802]; licodione 2'-O-methyltransferase activity [GO:0030751]; protein dimerization activity [GO:0046983]	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]; lignin biosynthetic process [GO:0009809]		lignin biosynthetic process [GO:0009809]			isoliquiritigenin 2'-O-methyltransferase activity [GO:0033802]; licodione 2'-O-methyltransferase activity [GO:0030751]; protein dimerization activity [GO:0046983]	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]
d1fp2a1_d5cvjd1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	isoflavone 7-O-methyltransferase activity [GO:0033800]; protein dimerization activity [GO:0046983]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]					isoflavone 7-O-methyltransferase activity [GO:0033800]; protein dimerization activity [GO:0046983]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]
d1fp2a2_d5ehic1__1	Viridiplantae		Streptophyta		isoflavone 7-O-methyltransferase activity [GO:0033800]; protein dimerization activity [GO:0046983]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	isoflavone 7-O-methyltransferase activity [GO:0033800]; protein dimerization activity [GO:0046983]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1fp3a__d3wkga___1	Metazoa		Chordata	Bacteroidetes	N-acylglucosamine 2-epimerase activity [GO:0050121]; peptidase inhibitor activity [GO:0030414]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]	cellobiose epimerase activity [GO:0047736]	N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]				N-acylglucosamine 2-epimerase activity [GO:0050121]; peptidase inhibitor activity [GO:0030414]	cellobiose epimerase activity [GO:0047736]
d1fp4d__d5cx1p___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1fp5a1_d3dgga2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fp6c__d2gbld1__1			Proteobacteria	Cyanobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]	circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]
d1fpmb__d1xd9a___1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; tetrahydrofolate interconversion [GO:0035999]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	tetrahydrofolate interconversion [GO:0035999]	nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1fpn3__d1zbe3___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1fpoa1_d2lgwa___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; iron-sulfur cluster transfer complex [GO:1990230]; ATPase activator activity [GO:0001671]; chaperone binding [GO:0051087]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein maturation by iron-sulfur cluster transfer [GO:0097428]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; extrinsic component of endoplasmic reticulum membrane [GO:0042406]; inclusion body [GO:0016234]; intrinsic component of endoplasmic reticulum membrane [GO:0031227]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ATPase activator activity [GO:0001671]; chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-dependent protein binding [GO:0140036]; unfolded protein binding [GO:0051082]; chaperone-mediated protein folding [GO:0061077]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of protein binding [GO:0032091]; negative regulation of protein deubiquitination [GO:0090086]; neuron cellular homeostasis [GO:0070050]; positive regulation of ATPase activity [GO:0032781]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein refolding [GO:0042026]; regulation of chaperone-mediated protein folding [GO:1903644]; regulation of protein localization [GO:0032880]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein maturation by iron-sulfur cluster transfer [GO:0097428]	chaperone-mediated protein folding [GO:0061077]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of protein binding [GO:0032091]; negative regulation of protein deubiquitination [GO:0090086]; neuron cellular homeostasis [GO:0070050]; positive regulation of ATPase activity [GO:0032781]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein refolding [GO:0042026]; regulation of chaperone-mediated protein folding [GO:1903644]; regulation of protein localization [GO:0032880]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; iron-sulfur cluster transfer complex [GO:1990230]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; extrinsic component of endoplasmic reticulum membrane [GO:0042406]; inclusion body [GO:0016234]; intrinsic component of endoplasmic reticulum membrane [GO:0031227]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	ATPase activator activity [GO:0001671]; chaperone binding [GO:0051087]	ATPase activator activity [GO:0001671]; chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]; ubiquitin-dependent protein binding [GO:0140036]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1fpob1_d2cuga1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; iron-sulfur cluster transfer complex [GO:1990230]; ATPase activator activity [GO:0001671]; chaperone binding [GO:0051087]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein maturation by iron-sulfur cluster transfer [GO:0097428]	cell [GO:0005623]; integral component of membrane [GO:0016021]; cell redox homeostasis [GO:0045454]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein maturation by iron-sulfur cluster transfer [GO:0097428]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; iron-sulfur cluster transfer complex [GO:1990230]	cell [GO:0005623]; integral component of membrane [GO:0016021]	ATPase activator activity [GO:0001671]; chaperone binding [GO:0051087]	
d1fpra__d4zn5a___1	Metazoa		Chordata	Proteobacteria	alpha-beta T cell receptor complex [GO:0042105]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cell adhesion molecule binding [GO:0050839]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; abortive mitotic cell cycle [GO:0033277]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein dephosphorylation [GO:0006470]; regulation of B cell differentiation [GO:0045577]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	abortive mitotic cell cycle [GO:0033277]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein dephosphorylation [GO:0006470]; regulation of B cell differentiation [GO:0045577]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]	pathogenesis [GO:0009405]	alpha-beta T cell receptor complex [GO:0042105]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	protein tyrosine phosphatase activity [GO:0004725]
d1fpra__d5kaba___1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cell adhesion molecule binding [GO:0050839]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; abortive mitotic cell cycle [GO:0033277]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein dephosphorylation [GO:0006470]; regulation of B cell differentiation [GO:0045577]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	abortive mitotic cell cycle [GO:0033277]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein dephosphorylation [GO:0006470]; regulation of B cell differentiation [GO:0045577]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	alpha-beta T cell receptor complex [GO:0042105]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cell adhesion molecule binding [GO:0050839]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1fpsa__d1v4eb___1	Metazoa		Chordata	Thermotogae	cytoplasm [GO:0005737]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	transferase activity [GO:0016740]; isoprenoid biosynthetic process [GO:0008299]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]		dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]	transferase activity [GO:0016740]
d1fpsa__d5dhka2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d1fpth1_d1s78f1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]
d1fpth2_d4nhub2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fptl1_d3idxl2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; entry into host cell [GO:0030260]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; entry into host cell [GO:0030260]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1fpwa__d2jula___1	Fungi	Metazoa	Ascomycota	Chordata	cellular bud membrane [GO:0033101]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; positive regulation of 1-phosphatidylinositol 4-kinase activity [GO:0043128]; regulation of signal transduction [GO:0009966]	axon [GO:0030424]; axon terminus [GO:0043679]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; voltage-gated potassium channel complex [GO:0008076]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; core promoter sequence-specific DNA binding [GO:0001046]; DNA binding [GO:0003677]; ion channel binding [GO:0044325]; magnesium ion binding [GO:0000287]; potassium channel activity [GO:0005267]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; sequence-specific DNA binding [GO:0043565]; voltage-gated ion channel activity [GO:0005244]; apoptotic process [GO:0006915]; behavioral response to pain [GO:0048266]; intracellular protein transport [GO:0006886]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; potassium ion transport [GO:0006813]; protein localization to plasma membrane [GO:0072659]; regulation of neuron apoptotic process [GO:0043523]; regulation of potassium ion transmembrane transport [GO:1901379]; response to pain [GO:0048265]; sensory perception of pain [GO:0019233]	positive regulation of 1-phosphatidylinositol 4-kinase activity [GO:0043128]; regulation of signal transduction [GO:0009966]	apoptotic process [GO:0006915]; behavioral response to pain [GO:0048266]; intracellular protein transport [GO:0006886]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; potassium ion transport [GO:0006813]; protein localization to plasma membrane [GO:0072659]; regulation of neuron apoptotic process [GO:0043523]; regulation of potassium ion transmembrane transport [GO:1901379]; response to pain [GO:0048265]; sensory perception of pain [GO:0019233]	cellular bud membrane [GO:0033101]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]	axon [GO:0030424]; axon terminus [GO:0043679]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; voltage-gated potassium channel complex [GO:0008076]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; core promoter sequence-specific DNA binding [GO:0001046]; DNA binding [GO:0003677]; ion channel binding [GO:0044325]; magnesium ion binding [GO:0000287]; potassium channel activity [GO:0005267]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; sequence-specific DNA binding [GO:0043565]; voltage-gated ion channel activity [GO:0005244]
d1fpyb2_d2df4b2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]; regulation of translational fidelity [GO:0006450]; translation [GO:0006412]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	regulation of translational fidelity [GO:0006450]; translation [GO:0006412]	cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]
d1fpyc1_d1htoi1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1fpyd1_d4lnnk1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1fpyd2_d2g5ib2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]; regulation of translational fidelity [GO:0006450]; translation [GO:0006412]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	regulation of translational fidelity [GO:0006450]; translation [GO:0006412]	cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]
d1fpye1_d4acfa1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1fpyf2_d1htog2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1fpyg1_d1htqs1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1fpyj1_d4lnnd1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1fpyj2_d1htqd2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1fpyj2_d1rl9a2__1		Metazoa	Proteobacteria	Arthropoda	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d1fpyk1_d4lnie1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1fpzf__d4bjoa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cell cycle arrest [GO:0007050]; cilium assembly [GO:0060271]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell population proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cell cycle arrest [GO:0007050]; cilium assembly [GO:0060271]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell population proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1fq0c__d3r8rg___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d1fq3a__d2uuya___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; natural killer cell mediated cytotoxicity [GO:0042267]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; natural killer cell mediated cytotoxicity [GO:0042267]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]	digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1fq4a__d3lzua___1	Fungi		Ascomycota		endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]; autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1fq7a__d5p6ma___1	Fungi	Fungi	Ascomycota	Ascomycota	endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]; autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	aspartic-type endopeptidase activity [GO:0004190]	autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]		endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]		aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]
d1fq8a__d1ztzb___1	Fungi		Ascomycota		endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]; autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1fq9c1_d1iray2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]	interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]
d1fq9d1_d1tzib2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]
d1fqda1_d4qsca___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	
d1fqja1_d1kjyc1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; protein folding [GO:0006457]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]; response to peptide hormone [GO:0043434]	adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; protein folding [GO:0006457]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]; response to peptide hormone [GO:0043434]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d1fqka1_d1agrd1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d1fqkd__d2bv1a___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; leukotriene signaling pathway [GO:0061737]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]	adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; leukotriene signaling pathway [GO:0061737]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	calmodulin binding [GO:0005516]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]
d1fqla__d4ygfa___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1fqoa__d4eu6b2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d1fqtb__d2de5c1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]	aromatic compound catabolic process [GO:0019439]	carbazole catabolic process [GO:0046232]			2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]
d1fqva2_d2astb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]
d1fqva2_d3tsre1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	angiogenin-PRI complex [GO:0032311]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; ribonuclease inhibitor activity [GO:0008428]; regulation of angiogenesis [GO:0045765]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	regulation of angiogenesis [GO:0045765]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	angiogenin-PRI complex [GO:0032311]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]	ribonuclease inhibitor activity [GO:0008428]
d1fqvo2_d2q4gy___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	extracellular exosome [GO:0070062]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	RNA phosphodiester bond hydrolysis [GO:0090501]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	extracellular exosome [GO:0070062]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]
d1fqwb__d1w25b2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]
d1fqwb__d3t8ya___1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; phosphorelay response regulator activity [GO:0000156]; protein-glutamate methylesterase activity [GO:0008984]; protein-glutamine glutaminase activity [GO:0050568]; chemotaxis [GO:0006935]; protein deamination [GO:0018277]; protein demethylation [GO:0006482]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	chemotaxis [GO:0006935]; protein deamination [GO:0018277]; protein demethylation [GO:0006482]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	phosphorelay response regulator activity [GO:0000156]; protein-glutamate methylesterase activity [GO:0008984]; protein-glutamine glutaminase activity [GO:0050568]
d1fqxa__d2i4xb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1fr3f__d1guoc___1			Firmicutes	Firmicutes	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]				
d1fr3l__d1gusd___1			Firmicutes	Firmicutes	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]				
d1fr7b__d4xixd___1	Metazoa	Viridiplantae	Chordata	Chlorophyta	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1frgh1_d1sy6a2__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	host cell surface receptor binding [GO:0046789]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]
d1frgl2_d3fruc1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	host cell surface receptor binding [GO:0046789]	
d1frha__d1bwea___1			Proteobacteria	Firmicutes	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1frma__d1gaoa___1			Proteobacteria	Proteobacteria	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1frna1_d3qfsa1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	photosynthesis [GO:0015979]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1frna2_d2b5oa2__1	Viridiplantae		Streptophyta	Cyanobacteria	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]	photosynthesis [GO:0015979]		chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]	ferredoxin-NADP+ reductase activity [GO:0004324]
d1frod__d4mtsa___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; pyruvate metabolic process [GO:0006090]; regulation of transcription by RNA polymerase II [GO:0006357]	lactoylglutathione lyase activity [GO:0004462]; metal ion binding [GO:0046872]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; pyruvate metabolic process [GO:0006090]; regulation of transcription by RNA polymerase II [GO:0006357]	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]	lactoylglutathione lyase activity [GO:0004462]; metal ion binding [GO:0046872]
d1frqa1_d5gv8a1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]	photosynthesis [GO:0015979]	cholesterol biosynthetic process [GO:0006695]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	ferredoxin-NADP+ reductase activity [GO:0004324]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1frqa2_d5thxa2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	photosynthesis [GO:0015979]		chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]		ferredoxin-NADP+ reductase activity [GO:0004324]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1frrb__d5c3jb1__1	Viridiplantae	Metazoa	Streptophyta	Nematoda (roundworms)	chloroplast [GO:0009507]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]	chloroplast [GO:0009507]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d1frtb__d4pbwe2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	axon [GO:0030424]; cytoplasm [GO:0005737]; integral component of plasma membrane [GO:0005887]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; p53 binding [GO:0002039]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of GTPase activity [GO:0090630]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; cellular response to nerve growth factor stimulus [GO:1990090]; circadian rhythm [GO:0007623]; heart development [GO:0007507]; lens fiber cell differentiation [GO:0070306]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of protein phosphorylation [GO:0001933]; nervous system development [GO:0007399]; neuronal action potential propagation [GO:0019227]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axon extension involved in regeneration [GO:0048691]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of synapse assembly [GO:0051965]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation of GTPase activity [GO:0090630]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; cellular response to nerve growth factor stimulus [GO:1990090]; circadian rhythm [GO:0007623]; heart development [GO:0007507]; lens fiber cell differentiation [GO:0070306]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of protein phosphorylation [GO:0001933]; nervous system development [GO:0007399]; neuronal action potential propagation [GO:0019227]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axon extension involved in regeneration [GO:0048691]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of synapse assembly [GO:0051965]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	axon [GO:0030424]; cytoplasm [GO:0005737]; integral component of plasma membrane [GO:0005887]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; p53 binding [GO:0002039]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1frtc1_d2gjza1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	metal ion binding [GO:0046872]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]			metal ion binding [GO:0046872]
d1frxa__d1ti4l2__1			Proteobacteria		3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	
d1frzb__d5dw6b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d1fs2a2_d1fqvm2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]
d1fs2a2_d4peqd___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]		cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	extracellular region [GO:0005576]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1fs2c2_d1k5gc___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1fs5a__d2nrbb2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrion [GO:0005739]	glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]
d1fsec__d1fc3a___1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; detection of stimulus [GO:0051606]; phosphorelay signal transduction system [GO:0000160]; regulation of sporulation resulting in formation of a cellular spore [GO:0042173]; sporulation resulting in formation of a cellular spore [GO:0030435]	regulation of transcription, DNA-templated [GO:0006355]	detection of stimulus [GO:0051606]; phosphorelay signal transduction system [GO:0000160]; regulation of sporulation resulting in formation of a cellular spore [GO:0042173]; sporulation resulting in formation of a cellular spore [GO:0030435]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]	calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1fsga1_d2e55a___1			Apicomplexa	Aquificae	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; xanthine phosphoribosyltransferase activity [GO:0000310]; GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	cytosol [GO:0005829]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; xanthine phosphoribosyltransferase activity [GO:0000310]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]
d1fsha__d1w4ma___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; Rac GTPase binding [GO:0048365]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; collateral sprouting [GO:0048668]; convergent extension involved in neural plate elongation [GO:0022007]; convergent extension involved in organogenesis [GO:0060029]; cytoplasmic microtubule organization [GO:0031122]; dendrite morphogenesis [GO:0048813]; dendritic spine morphogenesis [GO:0060997]; intracellular signal transduction [GO:0035556]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse organization [GO:0099173]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein localization to microtubule [GO:0035372]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cellular protein localization [GO:1903827]; regulation of neurotransmitter levels [GO:0001505]; regulation of protein phosphorylation [GO:0001932]; regulation of synaptic vesicle exocytosis [GO:2000300]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; social behavior [GO:0035176]; synapse organization [GO:0050808]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]; actin cytoskeleton reorganization [GO:0031532]; cell projection organization [GO:0030030]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G protein-coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin-activated receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904]	axon extension [GO:0048675]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; collateral sprouting [GO:0048668]; convergent extension involved in neural plate elongation [GO:0022007]; convergent extension involved in organogenesis [GO:0060029]; cytoplasmic microtubule organization [GO:0031122]; dendrite morphogenesis [GO:0048813]; dendritic spine morphogenesis [GO:0060997]; intracellular signal transduction [GO:0035556]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse organization [GO:0099173]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein localization to microtubule [GO:0035372]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cellular protein localization [GO:1903827]; regulation of neurotransmitter levels [GO:0001505]; regulation of protein phosphorylation [GO:0001932]; regulation of synaptic vesicle exocytosis [GO:2000300]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; social behavior [GO:0035176]; synapse organization [GO:0050808]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	actin cytoskeleton reorganization [GO:0031532]; cell projection organization [GO:0030030]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G protein-coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin-activated receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904]	axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; Rac GTPase binding [GO:0048365]	phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]
d1fskb1_d1nc4c2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fskc1_d2aq1g___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fskc1_d4aena2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1fskh1_d5m2mj1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d1fski2_d8fabb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fskk1_d2axhb2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fskk2_d6eljb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fskl1_d4jfxl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fsoa1_d3t5ia___1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	response to stimulus [GO:0050896]; visual perception [GO:0007601]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]
d1fspa__d2nt4a1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]		kinase activity [GO:0016301]; metal ion binding [GO:0046872]	
d1fsqb__d4xiwd___1	Metazoa	Viridiplantae	Chordata	Chlorophyta	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1fsxa__d1hjta___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1fsxb__d4l1ef___1	Metazoa		Chordata	Cyanobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1ft2b__d2wy8a___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d1ft3b1_d3edjb1__1	Metazoa		Chordata	Bacteroidetes	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	carbohydrate metabolic process [GO:0005975]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]		GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d1ft3b1_d3t5ic___1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	response to stimulus [GO:0050896]; visual perception [GO:0007601]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]
d1ft6a__d2rdzb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]; anaerobic electron transport chain [GO:0019645]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	anaerobic electron transport chain [GO:0019645]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]
d1ft8c1_d1kooa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1ft8c2_d3lpyb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; U2-type catalytic step 2 spliceosome [GO:0071007]; cyclosporin A binding [GO:0016018]; mRNA binding [GO:0003729]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; mRNA splicing, via spliceosome [GO:0000398]; neutrophil degranulation [GO:0043312]; positive regulation of viral genome replication [GO:0045070]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	mRNA splicing, via spliceosome [GO:0000398]; neutrophil degranulation [GO:0043312]; positive regulation of viral genome replication [GO:0045070]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; U2-type catalytic step 2 spliceosome [GO:0071007]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	cyclosporin A binding [GO:0016018]; mRNA binding [GO:0003729]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]
d1ft9a1_d1o3ra1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d1ft9a2_d3uknb___1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	integral component of plasma membrane [GO:0005887]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]; potassium ion transmembrane transporter activity [GO:0015079]; voltage-gated potassium channel activity [GO:0005249]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]		integral component of plasma membrane [GO:0005887]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]; potassium ion transmembrane transporter activity [GO:0015079]; voltage-gated potassium channel activity [GO:0005249]
d1ftjc__d1p1qc___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1ftjc__d4prsb___1	Metazoa		Chordata	Thermotogae	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	membrane [GO:0016020]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ligand-gated ion channel activity [GO:0015276]
d1ftma__d2vozb___1	Metazoa		Chordata	Cyanobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; thylakoid membrane [GO:0042651]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]; thylakoid membrane [GO:0042651]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	metal ion binding [GO:0046872]
d1ftna__d1z08d___1	Metazoa	Metazoa	Chordata	Chordata	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	axon cytoplasm [GO:1904115]; cleavage furrow [GO:0032154]; cytoplasmic side of early endosome membrane [GO:0098559]; cytoplasmic side of plasma membrane [GO:0009898]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi cisterna membrane [GO:0032580]; synapse [GO:0045202]; trans-Golgi network [GO:0005802]; vesicle membrane [GO:0012506]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; anterograde axonal transport [GO:0008089]; intracellular protein transport [GO:0006886]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of receptor-mediated endocytosis [GO:0048260]; Rab protein signal transduction [GO:0032482]; regulation of axon extension [GO:0030516]; regulation of exocytosis [GO:0017157]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	anterograde axonal transport [GO:0008089]; intracellular protein transport [GO:0006886]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of receptor-mediated endocytosis [GO:0048260]; Rab protein signal transduction [GO:0032482]; regulation of axon extension [GO:0030516]; regulation of exocytosis [GO:0017157]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	axon cytoplasm [GO:1904115]; cleavage furrow [GO:0032154]; cytoplasmic side of early endosome membrane [GO:0098559]; cytoplasmic side of plasma membrane [GO:0009898]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi cisterna membrane [GO:0032580]; synapse [GO:0045202]; trans-Golgi network [GO:0005802]; vesicle membrane [GO:0012506]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1ftra1_d1m5hh2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]
d1ftrc2_d2fhja1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]
d1ftrd1_d1ftrb2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]
d1ftsa1_d2c03b1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; signal recognition particle binding [GO:0005047]; protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]	signal recognition particle [GO:0048500]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; signal recognition particle binding [GO:0005047]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1ftsa2_d4gi7f___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; signal recognition particle binding [GO:0005047]; protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	coenzyme A biosynthetic process [GO:0015937]	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; signal recognition particle binding [GO:0005047]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d1fuea__d1bvyf___1			Proteobacteria	Firmicutes	FMN binding [GO:0010181]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	oxidation-reduction process [GO:0055114]			cytoplasm [GO:0005737]	FMN binding [GO:0010181]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d1fuga1_d4ndnd3__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d1fugb2_d3so4c2__1			Proteobacteria		cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d1fuia2_d4r1qb1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d1fuib2_d4c21a1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	L-fucose catabolic process [GO:0042355]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]
d1fuid1_d4r1qc2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d1fuie2_d4r1qc1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d1fujd__d5yjka___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; enzyme binding [GO:0019899]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; antimicrobial humoral response [GO:0019730]; blood coagulation [GO:0007596]; cell-cell junction maintenance [GO:0045217]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; mature conventional dendritic cell differentiation [GO:0097029]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of phagocytosis [GO:0050765]; neutrophil degranulation [GO:0043312]; neutrophil extravasation [GO:0072672]; phagocytosis [GO:0006909]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of GTPase activity [GO:0043547]; proteolysis [GO:0006508]	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	antimicrobial humoral response [GO:0019730]; blood coagulation [GO:0007596]; cell-cell junction maintenance [GO:0045217]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; mature conventional dendritic cell differentiation [GO:0097029]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of phagocytosis [GO:0050765]; neutrophil degranulation [GO:0043312]; neutrophil extravasation [GO:0072672]; phagocytosis [GO:0006909]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of GTPase activity [GO:0043547]; proteolysis [GO:0006508]	epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	enzyme binding [GO:0019899]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1func__d1uxlg___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1fund__d1sdya___1	Metazoa	Fungi	Chordata	Ascomycota	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]
d1fune__d1sxzb___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1funf__d1s4ic___1	Metazoa		Chordata	Firmicutes	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; removal of superoxide radicals [GO:0019430]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	removal of superoxide radicals [GO:0019430]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	plasma membrane [GO:0005886]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1fupa__d1fura___1			Proteobacteria	Proteobacteria	tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle enzyme complex [GO:0045239]	tricarboxylic acid cycle enzyme complex [GO:0045239]	fumarate hydratase activity [GO:0004333]	fumarate hydratase activity [GO:0004333]
d1fusa__d1g02a___1	Fungi	Fungi	Ascomycota	Ascomycota	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]				cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1futa__d2hohc___1	Fungi	Fungi	Ascomycota	Ascomycota	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]				cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1fv1a1_d2ht3f1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	
d1fv1a2_d1aqdb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]
d1fv1d1_d4pjee1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1fv1e1_d5vkkb1__1	Metazoa		Chordata		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	
d1fv1e2_d4p5mg1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d1fv2a1_d5nfaa___1		Metazoa	Firmicutes	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	negative regulation of neurotransmitter secretion [GO:0046929]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d1fv2a2_d1s0ea2__1			Firmicutes	Firmicutes	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1fvca__d2ckbi1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1fvda2_d1bfoa1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fvdb1_d5hdbl1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1fved2_d3l9rf___1		Metazoa		Chordata		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]		
d1fved2_d4untc___1		Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d1fvjb__d5b8bb___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]; activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]
d1fvka__d2hi7a1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d1fvoa1_d4kh1c1__1	Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; phosphate ion binding [GO:0042301]; phospholipid binding [GO:0005543]; ammonia homeostasis [GO:0097272]; anion homeostasis [GO:0055081]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; liver development [GO:0001889]; midgut development [GO:0007494]; ornithine catabolic process [GO:0006593]; protein homotrimerization [GO:0070207]; response to biotin [GO:0070781]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]		ammonia homeostasis [GO:0097272]; anion homeostasis [GO:0055081]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; liver development [GO:0001889]; midgut development [GO:0007494]; ornithine catabolic process [GO:0006593]; protein homotrimerization [GO:0070207]; response to biotin [GO:0070781]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; phosphate ion binding [GO:0042301]; phospholipid binding [GO:0005543]	
d1fvoa2_d3e2pe1__1	Metazoa		Chordata	Euryarchaeota	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; phosphate ion binding [GO:0042301]; phospholipid binding [GO:0005543]; ammonia homeostasis [GO:0097272]; anion homeostasis [GO:0055081]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; liver development [GO:0001889]; midgut development [GO:0007494]; ornithine catabolic process [GO:0006593]; protein homotrimerization [GO:0070207]; response to biotin [GO:0070781]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	ammonia homeostasis [GO:0097272]; anion homeostasis [GO:0055081]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; liver development [GO:0001889]; midgut development [GO:0007494]; ornithine catabolic process [GO:0006593]; protein homotrimerization [GO:0070207]; response to biotin [GO:0070781]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; phosphate ion binding [GO:0042301]; phospholipid binding [GO:0005543]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1fvob2_d4amud1__1	Metazoa		Chordata	Tenericutes	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; phosphate ion binding [GO:0042301]; phospholipid binding [GO:0005543]; ammonia homeostasis [GO:0097272]; anion homeostasis [GO:0055081]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; liver development [GO:0001889]; midgut development [GO:0007494]; ornithine catabolic process [GO:0006593]; protein homotrimerization [GO:0070207]; response to biotin [GO:0070781]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	ammonia homeostasis [GO:0097272]; anion homeostasis [GO:0055081]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; liver development [GO:0001889]; midgut development [GO:0007494]; ornithine catabolic process [GO:0006593]; protein homotrimerization [GO:0070207]; response to biotin [GO:0070781]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; phosphate ion binding [GO:0042301]; phospholipid binding [GO:0005543]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1fvua__d2ox8c___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	collagen trimer [GO:0005581]; endocytic vesicle membrane [GO:0030666]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; galactose binding [GO:0005534]; low-density lipoprotein particle binding [GO:0030169]; metal ion binding [GO:0046872]; scavenger receptor activity [GO:0005044]; signaling pattern recognition receptor activity [GO:0008329]; carbohydrate mediated signaling [GO:0009756]; cellular response to exogenous dsRNA [GO:0071360]; defense response [GO:0006952]; innate immune response [GO:0045087]; phagocytosis, recognition [GO:0006910]; positive regulation of cell adhesion molecule production [GO:0060355]; protein homooligomerization [GO:0051260]; receptor-mediated endocytosis [GO:0006898]; regulation of immune response [GO:0050776]; toll-like receptor 3 signaling pathway [GO:0034138]		carbohydrate mediated signaling [GO:0009756]; cellular response to exogenous dsRNA [GO:0071360]; defense response [GO:0006952]; innate immune response [GO:0045087]; phagocytosis, recognition [GO:0006910]; positive regulation of cell adhesion molecule production [GO:0060355]; protein homooligomerization [GO:0051260]; receptor-mediated endocytosis [GO:0006898]; regulation of immune response [GO:0050776]; toll-like receptor 3 signaling pathway [GO:0034138]	extracellular region [GO:0005576]	collagen trimer [GO:0005581]; endocytic vesicle membrane [GO:0030666]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	toxin activity [GO:0090729]	galactose binding [GO:0005534]; low-density lipoprotein particle binding [GO:0030169]; metal ion binding [GO:0046872]; scavenger receptor activity [GO:0005044]; signaling pattern recognition receptor activity [GO:0008329]
d1fvva__d4l3ja___1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; synapse [GO:0045202]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; PDZ domain binding [GO:0030165]; peptide binding [GO:0042277]; protein kinase activity [GO:0004672]; protein phosphatase 2A binding [GO:0051721]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; ribosomal protein S6 kinase activity [GO:0004711]; aging [GO:0007568]; apoptotic process [GO:0006915]; behavioral fear response [GO:0001662]; cell migration [GO:0016477]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; cellular response to interferon-gamma [GO:0071346]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell development [GO:0007281]; intracellular signal transduction [GO:0035556]; long-chain fatty acid import into cell [GO:0044539]; long-term memory [GO:0007616]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of glucose import [GO:0046324]; response to electrical stimulus involved in regulation of muscle adaptation [GO:0014878]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to leucine [GO:0043201]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to nutrient levels [GO:0031667]; response to testosterone [GO:0033574]; response to tumor necrosis factor [GO:0034612]; response to wounding [GO:0009611]; signal transduction [GO:0007165]; skeletal muscle atrophy [GO:0014732]; skeletal muscle contraction [GO:0003009]; TOR signaling [GO:0031929]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	aging [GO:0007568]; apoptotic process [GO:0006915]; behavioral fear response [GO:0001662]; cell migration [GO:0016477]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; cellular response to interferon-gamma [GO:0071346]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell development [GO:0007281]; intracellular signal transduction [GO:0035556]; long-chain fatty acid import into cell [GO:0044539]; long-term memory [GO:0007616]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of glucose import [GO:0046324]; response to electrical stimulus involved in regulation of muscle adaptation [GO:0014878]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to leucine [GO:0043201]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to nutrient levels [GO:0031667]; response to testosterone [GO:0033574]; response to tumor necrosis factor [GO:0034612]; response to wounding [GO:0009611]; signal transduction [GO:0007165]; skeletal muscle atrophy [GO:0014732]; skeletal muscle contraction [GO:0003009]; TOR signaling [GO:0031929]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; synapse [GO:0045202]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; PDZ domain binding [GO:0030165]; peptide binding [GO:0042277]; protein kinase activity [GO:0004672]; protein phosphatase 2A binding [GO:0051721]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; ribosomal protein S6 kinase activity [GO:0004711]
d1fvvb1_d4eomb2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1fvxa__d3nhra___1		Metazoa	Firmicutes	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1fw1a1_d1tu7a1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; maleylacetoacetate isomerase activity [GO:0016034]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; L-phenylalanine catabolic process [GO:0006559]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; tyrosine catabolic process [GO:0006572]	glutathione transferase activity [GO:0004364]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; L-phenylalanine catabolic process [GO:0006559]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; tyrosine catabolic process [GO:0006572]		cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; maleylacetoacetate isomerase activity [GO:0016034]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d1fw4a__d2fcea___1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]; calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]; calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; MIH complex [GO:0120155]; myosin II complex [GO:0016460]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; myosin II heavy chain binding [GO:0032038]; myosin V binding [GO:0031489]; actomyosin contractile ring assembly [GO:0000915]; protein localization [GO:0008104]; vesicle targeting [GO:0006903]	calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	actomyosin contractile ring assembly [GO:0000915]; protein localization [GO:0008104]; vesicle targeting [GO:0006903]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]	cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; MIH complex [GO:0120155]; myosin II complex [GO:0016460]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; myosin II heavy chain binding [GO:0032038]; myosin V binding [GO:0031489]
d1fw8a1_d5bt8a1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; oxidation-reduction process [GO:0055114]; positive regulation of oxidative phosphorylation [GO:1903862]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; oxidation-reduction process [GO:0055114]; positive regulation of oxidative phosphorylation [GO:1903862]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]	ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]
d1fwba__d4fura___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d1fwdb__d1e9za1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; pathogenesis [GO:0009405]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	pathogenesis [GO:0009405]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d1fwea__d4fure___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d1fwfb__d1e9ya1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; pathogenesis [GO:0009405]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	pathogenesis [GO:0009405]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d1fwka1_d1ueka1__1			Euryarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity [GO:0050515]; ATP binding [GO:0005524]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	threonine biosynthetic process [GO:0009088]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity [GO:0050515]; ATP binding [GO:0005524]
d1fwkb2_d2r3va2__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; peroxisome [GO:0005777]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]; cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; negative regulation of inflammatory response [GO:0050728]; regulation of cholesterol biosynthetic process [GO:0045540]	threonine biosynthetic process [GO:0009088]	cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; negative regulation of inflammatory response [GO:0050728]; regulation of cholesterol biosynthetic process [GO:0045540]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; peroxisome [GO:0005777]	ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]
d1fwkc2_d3d4ja2__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]	cytosol [GO:0005829]; ATP binding [GO:0005524]; diphosphomevalonate decarboxylase activity [GO:0004163]; Hsp70 protein binding [GO:0030544]; protein homodimerization activity [GO:0042803]; cholesterol biosynthetic process [GO:0006695]; dolichyl diphosphate biosynthetic process [GO:0006489]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; positive regulation of cell population proliferation [GO:0008284]; regulation of cholesterol biosynthetic process [GO:0045540]	threonine biosynthetic process [GO:0009088]	cholesterol biosynthetic process [GO:0006695]; dolichyl diphosphate biosynthetic process [GO:0006489]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; positive regulation of cell population proliferation [GO:0008284]; regulation of cholesterol biosynthetic process [GO:0045540]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]	ATP binding [GO:0005524]; diphosphomevalonate decarboxylase activity [GO:0004163]; Hsp70 protein binding [GO:0030544]; protein homodimerization activity [GO:0042803]
d1fwld2_d2ww4a2__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity [GO:0050515]; ATP binding [GO:0005524]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	threonine biosynthetic process [GO:0009088]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity [GO:0050515]; ATP binding [GO:0005524]
d1fwrc__d3undb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	metabolic process [GO:0008152]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]
d1fwua__d3aj5b1__1	Metazoa		Chordata		cell surface [GO:0009986]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cargo receptor activity [GO:0038024]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]	cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	pathogenesis [GO:0009405]	cell surface [GO:0009986]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	cargo receptor activity [GO:0038024]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]	carbohydrate binding [GO:0030246]
d1fwva__d4lo2b2__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cargo receptor activity [GO:0038024]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]		cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]		cell surface [GO:0009986]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		cargo receptor activity [GO:0038024]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]	
d1fwxb1_d3ag2b2__1		Metazoa	Proteobacteria	Chordata	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]	ATP synthesis coupled electron transport [GO:0042773]	membrane [GO:0016020]; periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1fwxc1_d4haka2__1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	denitrification pathway [GO:0019333]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	membrane [GO:0016020]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d1fwxc2_d2iwfb1__1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]	denitrification pathway [GO:0019333]	denitrification pathway [GO:0019333]	membrane [GO:0016020]; periplasmic space [GO:0042597]	membrane [GO:0016020]; periplasmic space [GO:0042597]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d1fwxd1_d1ibyb___1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]	metal ion binding [GO:0046872]	denitrification pathway [GO:0019333]		membrane [GO:0016020]; periplasmic space [GO:0042597]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	metal ion binding [GO:0046872]
d1fwya2_d1fzwa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1fwyb1_d1hm9b1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d1fx0a1_d3ziam3__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1fx0a3_d3tiva2__1	Viridiplantae		Streptophyta	Euryarchaeota	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1fx0b3_d1wp9c1__1	Viridiplantae		Streptophyta	Euryarchaeota	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; DNA repair [GO:0006281]	ATP synthesis coupled proton transport [GO:0015986]	DNA repair [GO:0006281]	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]
d1fx3a__d1qynd___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	cytosol [GO:0005829]; unfolded protein binding [GO:0051082]; chaperone-mediated protein transport [GO:0072321]; protein folding [GO:0006457]; protein localization [GO:0008104]; protein targeting [GO:0006605]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]; protein transport by the Sec complex [GO:0043952]	protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	chaperone-mediated protein transport [GO:0072321]; protein folding [GO:0006457]; protein localization [GO:0008104]; protein targeting [GO:0006605]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]; protein transport by the Sec complex [GO:0043952]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	unfolded protein binding [GO:0051082]	unfolded protein binding [GO:0051082]
d1fx3b__d5jtpd___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	unfolded protein binding [GO:0051082]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1fx3c__d5jtrc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cytoplasm [GO:0005737]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	unfolded protein binding [GO:0051082]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1fx3d__d5jtna___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	unfolded protein binding [GO:0051082]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1fx5b__d3b9cd___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; intracellular [GO:0005622]; carbohydrate binding [GO:0030246]				cytoplasm [GO:0005737]; intracellular [GO:0005622]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1fx9b__d4yu7b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]; bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]
d1fxaa__d5bysa1__1			Cyanobacteria	Firmicutes	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]
d1fxaa__d5gxgb___1			Cyanobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1fxab__d1e7ph2__1			Cyanobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]		respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d1fxab__d1iueb1__1			Cyanobacteria	Apicomplexa	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	apicoplast [GO:0020011]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		apicoplast [GO:0020011]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1fxh.1_d1gk1.2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]; glutaryl-7-aminocephalosporanic-acid acylase activity [GO:0033968]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]	glutaryl-7-aminocephalosporanic-acid acylase activity [GO:0033968]
d1fxia__d1e7pe2__1			Cyanobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]		respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d1fxib__d3p4sb1__1			Cyanobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1fxja2_d1hm8b2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d1fxjb1_d1yp2c1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	amyloplast [GO:0009501]; chloroplast [GO:0009507]; ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]; glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cytosol [GO:0005829]	amyloplast [GO:0009501]; chloroplast [GO:0009507]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]
d1fxjb2_d5uqta1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	host cell plasma membrane [GO:0020002]; cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	pathogenesis [GO:0009405]	cytosol [GO:0005829]	host cell plasma membrane [GO:0020002]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]
d1fxla1_d4cq1d2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; dendrite [GO:0030425]; growth cone [GO:0030426]; perikaryon [GO:0043204]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	cytoplasm [GO:0005737]; dendrite [GO:0030425]; growth cone [GO:0030426]; perikaryon [GO:0043204]; ribonucleoprotein complex [GO:1990904]	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]	mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1fxma__d1cxha4__1				Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1fxma__d1ogsa2__1		Metazoa		Chordata		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1fxoa__d2bo4c___1			Proteobacteria	Bacteroidetes	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]; mannosylglycerate biosynthetic process [GO:0051479]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	mannosylglycerate biosynthetic process [GO:0051479]			glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]
d1fxoc__d4fcua___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]		cytoplasm [GO:0005737]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]
d1fxof__d4ho3a___1			Proteobacteria	Firmicutes	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	extracellular polysaccharide biosynthetic process [GO:0045226]			glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1fxof__d4xwia___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]		cytosol [GO:0005829]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]
d1fxqa__d1zalb___1		Metazoa	Aquificae	Chordata	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]	I band [GO:0031674]; M band [GO:0031430]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	fructose-bisphosphate aldolase activity [GO:0004332]
d1fxta__d1q34c___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; ubiquitin conjugating enzyme complex [GO:0031371]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; ubiquitin conjugating enzyme complex [GO:0031371]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]
d1fxzb2_d2pa7a1__1	Viridiplantae		Streptophyta	Firmicutes	endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]	isomerase activity [GO:0016853]			endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]		nutrient reservoir activity [GO:0045735]	isomerase activity [GO:0016853]
d1fy4a__d1gbca___1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1fy7a__d2g3tb___1	Fungi	Metazoa	Ascomycota	Chordata	histone acetyltransferase complex [GO:0000123]; NuA4 histone acetyltransferase complex [GO:0035267]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; Piccolo NuA4 histone acetyltransferase complex [GO:0032777]; H4 histone acetyltransferase activity [GO:0010485]; histone acetyltransferase activity [GO:0004402]; histone binding [GO:0042393]; peptide N-acetyltransferase activity [GO:0034212]; chromatin silencing at rDNA [GO:0000183]; DNA repair [GO:0006281]; DNA-templated transcription, elongation [GO:0006354]; histone acetylation [GO:0016573]; histone displacement [GO:0001207]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of macroautophagy [GO:0016239]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]	cytosol [GO:0005829]; intracellular [GO:0005622]; diamine N-acetyltransferase activity [GO:0004145]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]; spermidine binding [GO:0019809]; angiogenesis [GO:0001525]; polyamine biosynthetic process [GO:0006596]; putrescine catabolic process [GO:0009447]; regulation of cell population proliferation [GO:0042127]; spermidine acetylation [GO:0032918]	chromatin silencing at rDNA [GO:0000183]; DNA repair [GO:0006281]; DNA-templated transcription, elongation [GO:0006354]; histone acetylation [GO:0016573]; histone displacement [GO:0001207]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of macroautophagy [GO:0016239]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]	angiogenesis [GO:0001525]; polyamine biosynthetic process [GO:0006596]; putrescine catabolic process [GO:0009447]; regulation of cell population proliferation [GO:0042127]; spermidine acetylation [GO:0032918]	histone acetyltransferase complex [GO:0000123]; NuA4 histone acetyltransferase complex [GO:0035267]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; Piccolo NuA4 histone acetyltransferase complex [GO:0032777]	cytosol [GO:0005829]; intracellular [GO:0005622]	H4 histone acetyltransferase activity [GO:0010485]; histone acetyltransferase activity [GO:0004402]; histone binding [GO:0042393]; peptide N-acetyltransferase activity [GO:0034212]	diamine N-acetyltransferase activity [GO:0004145]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]; spermidine binding [GO:0019809]
d1fy7a__d5us1c1__1	Fungi		Ascomycota	Proteobacteria	histone acetyltransferase complex [GO:0000123]; NuA4 histone acetyltransferase complex [GO:0035267]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; Piccolo NuA4 histone acetyltransferase complex [GO:0032777]; H4 histone acetyltransferase activity [GO:0010485]; histone acetyltransferase activity [GO:0004402]; histone binding [GO:0042393]; peptide N-acetyltransferase activity [GO:0034212]; chromatin silencing at rDNA [GO:0000183]; DNA repair [GO:0006281]; DNA-templated transcription, elongation [GO:0006354]; histone acetylation [GO:0016573]; histone displacement [GO:0001207]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of macroautophagy [GO:0016239]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]	aminoglycoside 2'-N-acetyltransferase activity [GO:0047921]; response to antibiotic [GO:0046677]	chromatin silencing at rDNA [GO:0000183]; DNA repair [GO:0006281]; DNA-templated transcription, elongation [GO:0006354]; histone acetylation [GO:0016573]; histone displacement [GO:0001207]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of macroautophagy [GO:0016239]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]	response to antibiotic [GO:0046677]	histone acetyltransferase complex [GO:0000123]; NuA4 histone acetyltransferase complex [GO:0035267]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; Piccolo NuA4 histone acetyltransferase complex [GO:0032777]		H4 histone acetyltransferase activity [GO:0010485]; histone acetyltransferase activity [GO:0004402]; histone binding [GO:0042393]; peptide N-acetyltransferase activity [GO:0034212]	aminoglycoside 2'-N-acetyltransferase activity [GO:0047921]
d1fy9a1_d1assa___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1fy9a1_d1kpoo2__1			Proteobacteria		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]		'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	
d1fyaa1_d1kp8c2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]
d1fyaa1_d1q2va2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1fyca__d1hpca___1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; identical protein binding [GO:0042802]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; pyruvate metabolic process [GO:0006090]; sleep [GO:0030431]; tricarboxylic acid cycle [GO:0006099]	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]; glycine decarboxylation via glycine cleavage system [GO:0019464]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; pyruvate metabolic process [GO:0006090]; sleep [GO:0030431]; tricarboxylic acid cycle [GO:0006099]	glycine decarboxylation via glycine cleavage system [GO:0019464]	mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254]	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; identical protein binding [GO:0042802]	
d1fyca__d3tzub___1	Metazoa		Chordata	Actinobacteria	mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; identical protein binding [GO:0042802]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; pyruvate metabolic process [GO:0006090]; sleep [GO:0030431]; tricarboxylic acid cycle [GO:0006099]	glycine cleavage complex [GO:0005960]; glycine decarboxylation via glycine cleavage system [GO:0019464]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; pyruvate metabolic process [GO:0006090]; sleep [GO:0030431]; tricarboxylic acid cycle [GO:0006099]	glycine decarboxylation via glycine cleavage system [GO:0019464]	mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254]	glycine cleavage complex [GO:0005960]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; identical protein binding [GO:0042802]	
d1fyfb2_d2dxtb1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d1fyha1_d3wcyi___1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interferon-gamma receptor activity [GO:0004906]; astrocyte activation [GO:0048143]; cytokine-mediated signaling pathway [GO:0019221]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of gene expression [GO:0010628]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; response to virus [GO:0009615]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; chloramphenicol O-acetyltransferase activity [GO:0008811]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; B cell activation involved in immune response [GO:0002312]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to dsRNA [GO:0071359]; cellular response to interferon-beta [GO:0035458]; cellular response to virus [GO:0098586]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; macrophage activation involved in immune response [GO:0002281]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	astrocyte activation [GO:0048143]; cytokine-mediated signaling pathway [GO:0019221]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of gene expression [GO:0010628]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; response to virus [GO:0009615]; signal transduction [GO:0007165]	adaptive immune response [GO:0002250]; B cell activation involved in immune response [GO:0002312]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to dsRNA [GO:0071359]; cellular response to interferon-beta [GO:0035458]; cellular response to virus [GO:0098586]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; macrophage activation involved in immune response [GO:0002281]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interferon-gamma receptor activity [GO:0004906]	chloramphenicol O-acetyltransferase activity [GO:0008811]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]
d1fyhe1_d3duha3__1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interferon-gamma receptor activity [GO:0004906]; astrocyte activation [GO:0048143]; cytokine-mediated signaling pathway [GO:0019221]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of gene expression [GO:0010628]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; response to virus [GO:0009615]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]; cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]	astrocyte activation [GO:0048143]; cytokine-mediated signaling pathway [GO:0019221]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of gene expression [GO:0010628]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; response to virus [GO:0009615]; signal transduction [GO:0007165]	cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interferon-gamma receptor activity [GO:0004906]	cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d1fyhe1_d4eq2a2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interferon-gamma receptor activity [GO:0004906]; astrocyte activation [GO:0048143]; cytokine-mediated signaling pathway [GO:0019221]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of gene expression [GO:0010628]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; response to virus [GO:0009615]; signal transduction [GO:0007165]	integral component of membrane [GO:0016021]; cytokine binding [GO:0019955]	astrocyte activation [GO:0048143]; cytokine-mediated signaling pathway [GO:0019221]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of gene expression [GO:0010628]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; response to virus [GO:0009615]; signal transduction [GO:0007165]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interferon-gamma receptor activity [GO:0004906]	cytokine binding [GO:0019955]
d1fysa__d1uckb___1	Fungi		Ascomycota	Actinobacteria	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1fytd1_d3qxtb___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1fyte1_d3b2ux2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d1fyzb__d4d8gd1__1			Proteobacteria	Chlamydiae	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1fyzc__d1r65a___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1fyzc__d4xkud___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1fyzd__d1piza___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1fyzd__d2yjje___1			Proteobacteria	Actinobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]
d1fz0a__d1jtsr___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]		cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1fz0a__d5tdvd___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	toluene catabolic process [GO:0042203]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1fz1a__d5d8qc___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1fz1b__d1iesa___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1fz2a__d1av8a___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1fz2a__d3hx2e___1			Proteobacteria		metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]		cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]				metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	
d1fz2b__d3pwqj1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	phenylacetate catabolic process [GO:0010124]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	
d1fz2c__d1fz3a___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1fz3a__d6enva___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1fz3c__d1jtsv___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]		cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1fz3d__d4tofc___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1fz4b__d4tobi___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1fz5a__d3a68k___1		Viridiplantae	Proteobacteria	Streptophyta	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1fz5d__d4xksf___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1fz6b__d3q14a___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	toluene catabolic process [GO:0042203]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1fz7a__d1xsma___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]		cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1fz7c__d3pwqb1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	phenylacetate catabolic process [GO:0010124]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	
d1fz8d__d1xvfa___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1fz9a__d4p1cd___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	toluene catabolic process [GO:0042203]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1fz9b__d1fz9d___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1fz9b__d1zs3g___1			Proteobacteria		metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]		cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]				metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	
d1fz9d__d1jtsl___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]		cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1fzab1_d1rf0f1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d1fzab1_d1z3uc1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]
d1fzbb1_d2j0hb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1fzbf1_d1z3ub1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]
d1fzcc1_d2j0ye___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1fzcf1_d1lwub1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	fibrinogen complex [GO:0005577]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]
d1fzda__d2j2pb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein-containing complex assembly [GO:0065003]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein polymerization [GO:0051258]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1fzdb__d2j3oa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein-containing complex assembly [GO:0065003]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein polymerization [GO:0051258]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1fzdd__d4r9tb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein-containing complex assembly [GO:0065003]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein polymerization [GO:0051258]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1fzde__d2j3uc___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein-containing complex assembly [GO:0065003]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein polymerization [GO:0051258]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1fzdg__d1fzfe1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein-containing complex assembly [GO:0065003]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein polymerization [GO:0051258]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d1fzeb1_d2j64b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1fzec1_d2j3gc___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1fzee1_d2j5za___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1fzfb1_d2j0ga___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1fzfe1_d2j5zc___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1fzff1_d1fzeb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d1fzhc__d1veia___1			Proteobacteria	Actinobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1fzhd__d4to9q___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1fzja1_d1axth2__1		Metazoa	Negarnaviricota	Chordata	helical viral capsid [GO:0019029]; host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]; virion [GO:0019012]; RNA binding [GO:0003723]; RNA replication [GO:0039703]; viral transcription [GO:0019083]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	RNA replication [GO:0039703]; viral transcription [GO:0019083]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	helical viral capsid [GO:0019029]; host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]; virion [GO:0019012]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	RNA binding [GO:0003723]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1fzkb__d2vyrk___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]
d1fznd__d3vb2a___1				Proteobacteria		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; cellular response to antibiotic [GO:0071236]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to heat [GO:0009408]		cellular response to antibiotic [GO:0071236]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to heat [GO:0009408]				DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]
d1fzoa1_d4nbxb___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	transferase activity, transferring glycosyl groups [GO:0016757]; pathogenesis [GO:0009405]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	pathogenesis [GO:0009405]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	transferase activity, transferring glycosyl groups [GO:0016757]
d1fzob__d5jdeb3__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1fzrd__d2a1ia1__1		Metazoa		Chordata	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	cytoplasm [GO:0005737]; ERCC4-ERCC1 complex [GO:0070522]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 1 complex [GO:0000110]; transcription factor TFIID complex [GO:0005669]; damaged DNA binding [GO:0003684]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; single-stranded DNA binding [GO:0003697]; single-stranded DNA endodeoxyribonuclease activity [GO:0000014]; TFIID-class transcription factor complex binding [GO:0001094]; cell population proliferation [GO:0008283]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; embryonic organ development [GO:0048568]; global genome nucleotide-excision repair [GO:0070911]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; male gonad development [GO:0008584]; meiotic mismatch repair [GO:0000710]; mitotic recombination [GO:0006312]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of telomere maintenance [GO:0032205]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; oogenesis [GO:0048477]; positive regulation of t-circle formation [GO:1904431]; post-embryonic hemopoiesis [GO:0035166]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; replicative cell aging [GO:0001302]; response to cadmium ion [GO:0046686]; response to immobilization stress [GO:0035902]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to sucrose [GO:0009744]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; syncytium formation [GO:0006949]; t-circle formation [GO:0090656]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650]; UV-damage excision repair [GO:0070914]	degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	cell population proliferation [GO:0008283]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; embryonic organ development [GO:0048568]; global genome nucleotide-excision repair [GO:0070911]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; male gonad development [GO:0008584]; meiotic mismatch repair [GO:0000710]; mitotic recombination [GO:0006312]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of telomere maintenance [GO:0032205]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; oogenesis [GO:0048477]; positive regulation of t-circle formation [GO:1904431]; post-embryonic hemopoiesis [GO:0035166]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; replicative cell aging [GO:0001302]; response to cadmium ion [GO:0046686]; response to immobilization stress [GO:0035902]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to sucrose [GO:0009744]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; syncytium formation [GO:0006949]; t-circle formation [GO:0090656]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV-damage excision repair [GO:0070914]; UV protection [GO:0009650]		cytoplasm [GO:0005737]; ERCC4-ERCC1 complex [GO:0070522]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 1 complex [GO:0000110]; transcription factor TFIID complex [GO:0005669]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]	damaged DNA binding [GO:0003684]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; single-stranded DNA binding [GO:0003697]; single-stranded DNA endodeoxyribonuclease activity [GO:0000014]; TFIID-class transcription factor complex binding [GO:0001094]
d1fzua__d1brsa___1	Fungi		Ascomycota	Firmicutes	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1fzwd__d5m7ca1__1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]		extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]
d1fzwe__d3pola1__1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]		cytoplasm [GO:0005737]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]
d1fzwf__d4ee4b___1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1fzwh__d1h5sa___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]		cytosol [GO:0005829]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1g07a__d219la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1g08a__d1yffc___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1g08b__d5b13f___1	Metazoa		Chordata	Rhodophyta	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1g0da1_d1nfib___1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; peptide cross-linking [GO:0018149]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	peptide cross-linking [GO:0018149]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1g0ja__d4lyma___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1g0oa__d1lu9c1__1	Fungi		Ascomycota	Proteobacteria	tetrahydroxynaphthalene reductase activity [GO:0047039]; melanin biosynthetic process [GO:0042438]	cytoplasm [GO:0005737]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	melanin biosynthetic process [GO:0042438]	formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]		cytoplasm [GO:0005737]	tetrahydroxynaphthalene reductase activity [GO:0047039]	methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]
d1g0ob__d4qxmc___1	Fungi		Ascomycota	Actinobacteria	tetrahydroxynaphthalene reductase activity [GO:0047039]; melanin biosynthetic process [GO:0042438]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	melanin biosynthetic process [GO:0042438]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]	tetrahydroxynaphthalene reductase activity [GO:0047039]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d1g0oc__d4ro0c1__1	Fungi		Ascomycota	Euryarchaeota	tetrahydroxynaphthalene reductase activity [GO:0047039]; melanin biosynthetic process [GO:0042438]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	melanin biosynthetic process [GO:0042438]	potassium ion transport [GO:0006813]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	tetrahydroxynaphthalene reductase activity [GO:0047039]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1g0pa__d5jwwa___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1g0qa__d1l7wa___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]	
d1g0ra__d2oi6a2__1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytosol [GO:0005829]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d1g0rb__d1h5sb___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]		cytosol [GO:0005829]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1g0rb__d2fydb1__1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1g0rg__d3k8db___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; magnesium ion binding [GO:0000287]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]		cytosol [GO:0005829]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; magnesium ion binding [GO:0000287]
d1g0ta1_d2vupa___1			Proteobacteria		cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	glutathione peroxidase activity [GO:0004602]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	response to oxidative stress [GO:0006979]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione peroxidase activity [GO:0004602]
d1g0uj__d5jhre___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g0un__d4hnzc1__1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; HslUV protease complex [GO:0009376]; kinetoplast [GO:0020023]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nuclear lumen [GO:0031981]; proteasome core complex [GO:0005839]; ATP-dependent peptidase activity [GO:0004176]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; mitochondrial DNA inheritance [GO:0033955]; mitochondrial DNA replication [GO:0006264]; proteolysis involved in cellular protein catabolic process [GO:0051603]; rolling circle DNA replication [GO:0070581]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	mitochondrial DNA inheritance [GO:0033955]; mitochondrial DNA replication [GO:0006264]; proteolysis involved in cellular protein catabolic process [GO:0051603]; rolling circle DNA replication [GO:0070581]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; HslUV protease complex [GO:0009376]; kinetoplast [GO:0020023]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nuclear lumen [GO:0031981]; proteasome core complex [GO:0005839]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	ATP-dependent peptidase activity [GO:0004176]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g0uu__d1rypv___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g0uv__d4qv7t___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g0ux__d3c91u1__1	Fungi		Ascomycota	Euryarchaeota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g0uz__d5fgib___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g0va__d3b80b___1	Fungi		Ascomycota		endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]; autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1g0wa1_d3l2fd1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]		phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]		cytoplasm [GO:0005737]; extracellular space [GO:0005615]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]	
d1g0yr3_d1fq9d1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]
d1g12a__d1oz9a___1	Fungi		Basidiomycota	Aquificae	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cytoplasm [GO:0005737]; endoribonuclease activity [GO:0004521]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; rRNA processing [GO:0006364]		rRNA processing [GO:0006364]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	endoribonuclease activity [GO:0004521]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1g1fa__d4y2ea___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; activation of MAPK activity [GO:0000187]; MAPK cascade [GO:0000165]; negative regulation of MAP kinase activity [GO:0043407]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	activation of MAPK activity [GO:0000187]; MAPK cascade [GO:0000165]; negative regulation of MAP kinase activity [GO:0043407]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1g1kb1_d4tf4a2__1			Firmicutes	Actinobacteria	cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]			cellulose binding [GO:0030248]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d1g1ld__d1hjja___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]; bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]		cytoplasm [GO:0005737]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]
d1g1ob__d4tkwa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1g1oc__d3grba___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1g1qa1_d4gi0c___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d1g1qb1_d5m62a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	integral component of plasma membrane [GO:0005887]; carbohydrate binding [GO:0030246]; defense response to virus [GO:0051607]	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	defense response to virus [GO:0051607]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]	integral component of plasma membrane [GO:0005887]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]	carbohydrate binding [GO:0030246]
d1g1qc1_d1tdqb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	extracellular matrix [GO:0031012]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; perisynaptic extracellular matrix [GO:0098966]; integrin binding [GO:0005178]; cell adhesion [GO:0007155]; negative regulation of cell adhesion [GO:0007162]; nervous system development [GO:0007399]; regulation of neurogenesis [GO:0050767]	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	cell adhesion [GO:0007155]; negative regulation of cell adhesion [GO:0007162]; nervous system development [GO:0007399]; regulation of neurogenesis [GO:0050767]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]	extracellular matrix [GO:0031012]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; perisynaptic extracellular matrix [GO:0098966]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]	integrin binding [GO:0005178]
d1g1ra1_d3wbrg___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; adaptive immune response [GO:0002250]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	adaptive immune response [GO:0002250]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]	ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; tertiary granule membrane [GO:0070821]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1g1rb1_d2riec1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1g1rc1_d1tsga___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]		calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]	
d1g1sa1_d3alud___1	Metazoa	Metazoa	Chordata	Echinodermata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	metal ion binding [GO:0046872]	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]	metal ion binding [GO:0046872]
d1g1sb1_d3dbzc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1g1ta1_d1g1sb1__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; clathrin-coated pit [GO:0005905]; cortical cytoskeleton [GO:0030863]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; oligosaccharide binding [GO:0070492]; phospholipase binding [GO:0043274]; sialic acid binding [GO:0033691]; transmembrane signaling receptor activity [GO:0004888]; actin filament-based process [GO:0030029]; activation of phospholipase C activity [GO:0007202]; calcium-mediated signaling [GO:0019722]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte migration involved in inflammatory response [GO:0002523]; leukocyte tethering or rolling [GO:0050901]; positive regulation of receptor internalization [GO:0002092]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	actin filament-based process [GO:0030029]; activation of phospholipase C activity [GO:0007202]; calcium-mediated signaling [GO:0019722]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte migration involved in inflammatory response [GO:0002523]; leukocyte tethering or rolling [GO:0050901]; positive regulation of receptor internalization [GO:0002092]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	caveola [GO:0005901]; clathrin-coated pit [GO:0005905]; cortical cytoskeleton [GO:0030863]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]	metal ion binding [GO:0046872]; oligosaccharide binding [GO:0070492]; phospholipase binding [GO:0043274]; sialic acid binding [GO:0033691]; transmembrane signaling receptor activity [GO:0004888]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]
d1g1wa__d4i7rb1__1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1g1xb__d1hnxo___1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1g1ya3_d1h4pb___1		Fungi	Firmicutes	Ascomycota	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; fungal-type vacuole [GO:0000324]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]	carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]		extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; fungal-type vacuole [GO:0000324]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	glucan exo-1,3-beta-glucosidase activity [GO:0004338]
d1g1yb1_d4gsxb2__1			Firmicutes		metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1g1yb3_d1ocqa___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]
d1g20a__d3pdic___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]; protein-containing complex assembly [GO:0065003]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]; protein-containing complex assembly [GO:0065003]	molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1g20b__d5lwqc1__1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	metal ion binding [GO:0046872]; iron ion transport [GO:0006826]	nitrogen fixation [GO:0009399]	iron ion transport [GO:0006826]	molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	metal ion binding [GO:0046872]
d1g21b__d1n2ca___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1g21d__d1m1ng___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1g21d__d3zttc___1			Proteobacteria	Firmicutes	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	nitrogen fixation [GO:0009399]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	molybdenum-iron nitrogenase complex [GO:0016612]	plasma membrane [GO:0005886]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	metal ion binding [GO:0046872]
d1g21e__d1a2kd___1		Metazoa	Proteobacteria	Chordata	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	nitrogen fixation [GO:0009399]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	molybdenum-iron nitrogenase complex [GO:0016612]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]
d1g24b__d4gv7b2__1		Metazoa		Chordata	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	transferase activity, transferring pentosyl groups [GO:0016763]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1g24d__d2pa9a2__1					extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]		pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]		extracellular region [GO:0005576]		transferase activity, transferring pentosyl groups [GO:0016763]	
d1g27c__d3g5kc1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; positive regulation of cell population proliferation [GO:0008284]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; positive regulation of cell population proliferation [GO:0008284]; translation [GO:0006412]	cytosol [GO:0005829]	mitochondrion [GO:0005739]	ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d1g28c__d2z6cb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vacuole [GO:0005773]; ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; mRNA binding [GO:0003729]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; chloroplast accumulation movement [GO:0009904]; chloroplast avoidance movement [GO:0009903]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-chromophore linkage [GO:0018298]; regulation of proton transport [GO:0010155]; regulation of stomatal movement [GO:0010119]; response to blue light [GO:0009637]	detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	chloroplast accumulation movement [GO:0009904]; chloroplast avoidance movement [GO:0009903]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; protein phosphorylation [GO:0006468]; regulation of proton transport [GO:0010155]; regulation of stomatal movement [GO:0010119]; response to blue light [GO:0009637]		cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vacuole [GO:0005773]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]	ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; mRNA binding [GO:0003729]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d1g2kb__d3pm4a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1g2oa__d3phbe1__1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; purine-nucleoside phosphorylase activity [GO:0004731]; deoxyguanosine catabolic process [GO:0006161]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	deoxyguanosine catabolic process [GO:0006161]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	purine-nucleoside phosphorylase activity [GO:0004731]	drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]
d1g2oa__d4txlc___1		Metazoa	Actinobacteria	Platyhelminthes	cytoplasm [GO:0005737]; purine-nucleoside phosphorylase activity [GO:0004731]; deoxyguanosine catabolic process [GO:0006161]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]	deoxyguanosine catabolic process [GO:0006161]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	purine-nucleoside phosphorylase activity [GO:0004731]	uridine phosphorylase activity [GO:0004850]
d1g2ob__d3uaya___1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; purine-nucleoside phosphorylase activity [GO:0004731]; deoxyguanosine catabolic process [GO:0006161]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	deoxyguanosine catabolic process [GO:0006161]	purine nucleoside metabolic process [GO:0042278]	cytoplasm [GO:0005737]		purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d1g2qb__d2ehjc1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; adenine binding [GO:0002055]; adenine phosphoribosyltransferase activity [GO:0003999]; AMP binding [GO:0016208]; metal ion binding [GO:0046872]; adenine salvage [GO:0006168]; AMP biosynthetic process [GO:0006167]; AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]	cytosol [GO:0005829]; membrane [GO:0016020]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	adenine salvage [GO:0006168]; AMP biosynthetic process [GO:0006167]; AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; membrane [GO:0016020]	adenine binding [GO:0002055]; adenine phosphoribosyltransferase activity [GO:0003999]; AMP binding [GO:0016208]; metal ion binding [GO:0046872]	GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]
d1g2ua__d4zdaf___1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]		3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]
d1g2vd__d4ee5c___1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1g2ve__d1h7hb___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]		cytoplasm [GO:0005737]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]
d1g2xc__d1g0zb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1g31c__d1aont___1				Proteobacteria	protein folding [GO:0006457]; viral capsid assembly [GO:0019069]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	protein folding [GO:0006457]; viral capsid assembly [GO:0019069]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d1g31g__d1pf9q___1				Proteobacteria	protein folding [GO:0006457]; viral capsid assembly [GO:0019069]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	protein folding [GO:0006457]; viral capsid assembly [GO:0019069]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d1g31g__d4pj121__1		Metazoa		Chordata	protein folding [GO:0006457]; viral capsid assembly [GO:0019069]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; chaperone cofactor-dependent protein refolding [GO:0051085]; osteoblast differentiation [GO:0001649]; protein folding [GO:0006457]; response to unfolded protein [GO:0006986]	protein folding [GO:0006457]; viral capsid assembly [GO:0019069]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; chaperone cofactor-dependent protein refolding [GO:0051085]; osteoblast differentiation [GO:0001649]; protein folding [GO:0006457]; response to unfolded protein [GO:0006986]		extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]
d1g32.1_d1z8ra___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1g33a__d2h61f___1	Metazoa	Metazoa	Chordata	Chordata	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cochlea development [GO:0090102]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cochlea development [GO:0090102]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1g38a1_d1rjdc1__1		Fungi	Deinococcus-Thermus	Ascomycota	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; C-terminal protein methylation [GO:0006481]; cellular protein-containing complex assembly [GO:0034622]; regulation of autophagy [GO:0010506]	DNA restriction-modification system [GO:0009307]	cellular protein-containing complex assembly [GO:0034622]; C-terminal protein methylation [GO:0006481]; regulation of autophagy [GO:0010506]			DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]
d1g38a2_d2ih5a2__1			Deinococcus-Thermus	Deinococcus-Thermus	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]
d1g3ba__d5h4ib___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	fusion of virus membrane with host endosome membrane [GO:0039654]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1g3ea__d4wh8b1__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1g3ga__d2feza3__1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; GTPase activity [GO:0003924]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]	ATPase activity [GO:0016887]; DNA binding [GO:0003677]; GTPase activity [GO:0003924]
d1g3ig__d5l64p___1		Fungi	Proteobacteria	Ascomycota	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein unfolding [GO:0043335]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g3ih__d2gplm___1		Fungi	Proteobacteria	Ascomycota	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein unfolding [GO:0043335]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g3ik__d4qw1i___1		Fungi	Proteobacteria	Ascomycota	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein unfolding [GO:0043335]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g3il__d1eccb2__1			Proteobacteria	Proteobacteria	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	protein unfolding [GO:0043335]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	HslUV protease complex [GO:0009376]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]
d1g3io__d5l65z___1		Fungi	Proteobacteria	Ascomycota	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein unfolding [GO:0043335]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g3ir__d2z3bl___1			Proteobacteria	Firmicutes	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	protein unfolding [GO:0043335]	proteolysis involved in cellular protein catabolic process [GO:0051603]	HslUV protease complex [GO:0009376]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]
d1g3kc__d3un8s___1		Fungi	Proteobacteria	Ascomycota	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g3la__d4eeac___1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1g3lc__d1jn8b___1			Proteobacteria		glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]				glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	
d1g3ma__d3oe7o2__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; estrone sulfotransferase activity [GO:0004304]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid binding [GO:0005496]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; estrogen catabolic process [GO:0006711]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; positive regulation of fat cell differentiation [GO:0045600]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; estrogen catabolic process [GO:0006711]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; positive regulation of fat cell differentiation [GO:0045600]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]	ATP synthesis coupled proton transport [GO:0015986]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	estrone sulfotransferase activity [GO:0004304]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid binding [GO:0005496]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1g3nf__d1dc2a___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]; astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; senescence-associated heterochromatin focus [GO:0035985]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; NF-kappaB binding [GO:0051059]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; cell cycle arrest [GO:0007050]; cellular senescence [GO:0090398]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of phosphorylation [GO:0042326]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cellular senescence [GO:2000774]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; Ras protein signal transduction [GO:0007265]; replicative senescence [GO:0090399]; senescence-associated heterochromatin focus assembly [GO:0035986]	astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	cell cycle arrest [GO:0007050]; cellular senescence [GO:0090398]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of phosphorylation [GO:0042326]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cellular senescence [GO:2000774]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; Ras protein signal transduction [GO:0007265]; replicative senescence [GO:0090399]; senescence-associated heterochromatin focus assembly [GO:0035986]	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; senescence-associated heterochromatin focus [GO:0035985]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]	cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; NF-kappaB binding [GO:0051059]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d1g3ng1_d1c9bm1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]; astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1g3ng1_d3ddqb2__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]; astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1g3oa__d1h98a___1			Proteobacteria	Deinococcus-Thermus	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1g43a__d3zu8a1__1			Firmicutes	Firmicutes	cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]			cellulose binding [GO:0030248]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d1g49a__d1xucb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1g4bo__d5lf3i___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g4bp__d3unfq___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g4ka__d1kbca___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1g4kc__d3fxpa___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1g4ma1_d1xwvb___1	Metazoa	Metazoa	Chordata	Arthropoda	clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; acetylcholine receptor binding [GO:0033130]; AP-2 adaptor complex binding [GO:0035612]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein homodimerization activity [GO:0042803]; clathrin-dependent endocytosis [GO:0072583]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	extracellular region [GO:0005576]	clathrin-dependent endocytosis [GO:0072583]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]		clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]	extracellular region [GO:0005576]	acetylcholine receptor binding [GO:0033130]; AP-2 adaptor complex binding [GO:0035612]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein homodimerization activity [GO:0042803]	
d1g4mb1_d2diba1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; acetylcholine receptor binding [GO:0033130]; AP-2 adaptor complex binding [GO:0035612]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein homodimerization activity [GO:0042803]; clathrin-dependent endocytosis [GO:0072583]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	clathrin-dependent endocytosis [GO:0072583]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	acetylcholine receptor binding [GO:0033130]; AP-2 adaptor complex binding [GO:0035612]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d1g4ra1_d1ayrd1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; acetylcholine receptor binding [GO:0033130]; AP-2 adaptor complex binding [GO:0035612]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein homodimerization activity [GO:0042803]; clathrin-dependent endocytosis [GO:0072583]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]; G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	clathrin-dependent endocytosis [GO:0072583]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	acetylcholine receptor binding [GO:0033130]; AP-2 adaptor complex binding [GO:0035612]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein homodimerization activity [GO:0042803]	G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]
d1g4sa1_d2tpsa1__1			Firmicutes	Firmicutes	magnesium ion binding [GO:0000287]; thiamine-phosphate diphosphorylase activity [GO:0004789]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	magnesium ion binding [GO:0000287]; thiamine-phosphate diphosphorylase activity [GO:0004789]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]			magnesium ion binding [GO:0000287]; thiamine-phosphate diphosphorylase activity [GO:0004789]	magnesium ion binding [GO:0000287]; thiamine-phosphate diphosphorylase activity [GO:0004789]
d1g4ur__d5citb___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; histone deacetylase binding [GO:0042826]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cell-matrix adhesion [GO:0007160]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; histone deacetylase binding [GO:0042826]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1g4wr2_d3bm8a___1			Proteobacteria	Proteobacteria	extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; GTPase activator activity [GO:0005096]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]	extracellular region [GO:0005576]	GTPase activator activity [GO:0005096]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d1g4yr__d5hlve1__1	Metazoa	Metazoa	Chordata	Chordata	dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; small conductance calcium-activated potassium channel activity [GO:0016286]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of neuronal synaptic plasticity [GO:0048168]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of neuronal synaptic plasticity [GO:0048168]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calmodulin binding [GO:0005516]; small conductance calcium-activated potassium channel activity [GO:0016286]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1g50b__d2om9a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transcriptional preinitiation complex [GO:0097550]; transcriptionally active chromatin [GO:0035327]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor activity [GO:0030284]; estrogen receptor binding [GO:0030331]; estrogen response element binding [GO:0034056]; identical protein binding [GO:0042802]; nitric-oxide synthase regulator activity [GO:0030235]; nuclear receptor activity [GO:0004879]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; steroid binding [GO:0005496]; TBP-class protein binding [GO:0017025]; TFIIB-class transcription factor binding [GO:0001093]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; androgen metabolic process [GO:0008209]; antral ovarian follicle growth [GO:0001547]; cellular response to estradiol stimulus [GO:0071392]; cellular response to estrogen stimulus [GO:0071391]; chromatin remodeling [GO:0006338]; epithelial cell development [GO:0002064]; epithelial cell proliferation involved in mammary gland duct elongation [GO:0060750]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; male gonad development [GO:0008584]; mammary gland alveolus development [GO:0060749]; mammary gland branching involved in pregnancy [GO:0060745]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; protein deubiquitination [GO:0016579]; protein localization to chromatin [GO:0071168]; regulation of apoptotic process [GO:0042981]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of inflammatory response [GO:0050727]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; signal transduction [GO:0007165]; stem cell differentiation [GO:0048863]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]; uterus development [GO:0060065]; vagina development [GO:0060068]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]; activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	androgen metabolic process [GO:0008209]; antral ovarian follicle growth [GO:0001547]; cellular response to estradiol stimulus [GO:0071392]; cellular response to estrogen stimulus [GO:0071391]; chromatin remodeling [GO:0006338]; epithelial cell development [GO:0002064]; epithelial cell proliferation involved in mammary gland duct elongation [GO:0060750]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; male gonad development [GO:0008584]; mammary gland alveolus development [GO:0060749]; mammary gland branching involved in pregnancy [GO:0060745]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; protein deubiquitination [GO:0016579]; protein localization to chromatin [GO:0071168]; regulation of apoptotic process [GO:0042981]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of inflammatory response [GO:0050727]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; signal transduction [GO:0007165]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; uterus development [GO:0060065]; vagina development [GO:0060068]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transcriptionally active chromatin [GO:0035327]; transcriptional preinitiation complex [GO:0097550]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]	ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor activity [GO:0030284]; estrogen receptor binding [GO:0030331]; estrogen response element binding [GO:0034056]; identical protein binding [GO:0042802]; nitric-oxide synthase regulator activity [GO:0030235]; nuclear receptor activity [GO:0004879]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; steroid binding [GO:0005496]; TBP-class protein binding [GO:0017025]; TFIIB-class transcription factor binding [GO:0001093]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]
d1g51a1_d2q2uc1__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]	aspartyl-tRNA aminoacylation [GO:0006422]	DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]	cytoplasm [GO:0005737]		aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]	ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]
d1g51b2_d1zq1c2__1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]; translation [GO:0006412]	aspartyl-tRNA aminoacylation [GO:0006422]	translation [GO:0006412]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]
d1g5aa1_d1v3ma3__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	amylosucrase activity [GO:0047669]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1g5aa2_d2qpsa2__1		Viridiplantae	Proteobacteria	Streptophyta	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	amylosucrase activity [GO:0047669]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1g5bb__d3qfoa___1				Firmicutes	metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]	nucleotide binding [GO:0000166]					metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]	nucleotide binding [GO:0000166]
d1g5bc__d3e7aa___1		Metazoa		Chordata	metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]	cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]
d1g5id1_d4hwtb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; respiratory electron transport chain [GO:0022904]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; respiratory electron transport chain [GO:0022904]	threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]
d1g5na__d1w3wa___1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; blood coagulation [GO:0007596]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of serine-type endopeptidase activity [GO:1900004]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	blood coagulation [GO:0007596]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of serine-type endopeptidase activity [GO:1900004]	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]	actin filament binding [GO:0051015]; calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]
d1g5pa__d1lnya___1		Metazoa	Proteobacteria	Chordata	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; membrane [GO:0016020]; actin filament binding [GO:0051015]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; 'de novo' AMP biosynthetic process [GO:0044208]; AMP biosynthetic process [GO:0006167]; aspartate metabolic process [GO:0006531]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; glutamine metabolic process [GO:0006541]; IMP metabolic process [GO:0046040]; purine nucleotide metabolic process [GO:0006163]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to muscle activity [GO:0014850]; response to starvation [GO:0042594]	nitrogen fixation [GO:0009399]	'de novo' AMP biosynthetic process [GO:0044208]; AMP biosynthetic process [GO:0006167]; aspartate metabolic process [GO:0006531]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; glutamine metabolic process [GO:0006541]; IMP metabolic process [GO:0046040]; purine nucleotide metabolic process [GO:0006163]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to muscle activity [GO:0014850]; response to starvation [GO:0042594]	molybdenum-iron nitrogenase complex [GO:0016612]	cytoplasm [GO:0005737]; membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	actin filament binding [GO:0051015]; adenylosuccinate synthase activity [GO:0004019]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]
d1g5wa__d5dpqb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	cytosol [GO:0005829]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1g5xa1_d1ek4c2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1g5xa1_d4jaqa1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	polyketide synthase complex [GO:0034081]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	polyketide synthase complex [GO:0034081]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1g5xa2_d4dfea2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1g5xb2_d4c6zb2__1			Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	
d1g5xc1_d4nhdb2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1g5xd2_d3h76a1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]; fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]
d1g5yc__d4n1ya___1	Metazoa	Metazoa	Chordata	Mollusca	mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]; chromatin DNA binding [GO:0031490]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; nuclear receptor activity [GO:0004879]; nuclear receptor binding [GO:0016922]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; retinoic acid binding [GO:0001972]; retinoic acid-responsive element binding [GO:0044323]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription coactivator activity [GO:0003713]; vitamin D receptor binding [GO:0042809]; zinc ion binding [GO:0008270]; anatomical structure development [GO:0048856]; bile acid and bile salt transport [GO:0015721]; camera-type eye development [GO:0043010]; cardiac muscle cell proliferation [GO:0060038]; cell differentiation [GO:0030154]; cholesterol metabolic process [GO:0008203]; embryo implantation [GO:0007566]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; modulation by virus of host morphology or physiology [GO:0019048]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ventricular cardiac muscle cell differentiation [GO:0055012]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; vitamin metabolic process [GO:0006766]	nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]	anatomical structure development [GO:0048856]; bile acid and bile salt transport [GO:0015721]; camera-type eye development [GO:0043010]; cardiac muscle cell proliferation [GO:0060038]; cell differentiation [GO:0030154]; cholesterol metabolic process [GO:0008203]; embryo implantation [GO:0007566]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; modulation by virus of host morphology or physiology [GO:0019048]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ventricular cardiac muscle cell differentiation [GO:0055012]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; vitamin metabolic process [GO:0006766]		mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]	nucleus [GO:0005634]	chromatin DNA binding [GO:0031490]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; nuclear receptor activity [GO:0004879]; nuclear receptor binding [GO:0016922]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; retinoic acid binding [GO:0001972]; retinoic acid-responsive element binding [GO:0044323]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription coactivator activity [GO:0003713]; vitamin D receptor binding [GO:0042809]; zinc ion binding [GO:0008270]	DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]
d1g5za__d2ga0b___1			Spirochaetes	Spirochaetes	cell outer membrane [GO:0009279]	cell outer membrane [GO:0009279]			cell outer membrane [GO:0009279]	cell outer membrane [GO:0009279]		
d1g61a__d2c6za___1		Metazoa	Euryarchaeota	Chordata	cytosol [GO:0005829]; nucleolus [GO:0005730]; preribosome, large subunit precursor [GO:0030687]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]; translation initiation factor activity [GO:0003743]; assembly of large subunit precursor of preribosome [GO:1902626]; mature ribosome assembly [GO:0042256]; ribosomal subunit export from nucleus [GO:0000054]	amino acid binding [GO:0016597]; dimethylargininase activity [GO:0016403]; zinc ion binding [GO:0008270]; arginine catabolic process [GO:0006527]; arginine metabolic process [GO:0006525]; citrulline metabolic process [GO:0000052]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of vascular permeability [GO:0043116]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein nitrosylation [GO:0017014]; regulation of systemic arterial blood pressure [GO:0003073]	assembly of large subunit precursor of preribosome [GO:1902626]; mature ribosome assembly [GO:0042256]; ribosomal subunit export from nucleus [GO:0000054]	arginine catabolic process [GO:0006527]; arginine metabolic process [GO:0006525]; citrulline metabolic process [GO:0000052]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of vascular permeability [GO:0043116]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein nitrosylation [GO:0017014]; regulation of systemic arterial blood pressure [GO:0003073]	cytosol [GO:0005829]; nucleolus [GO:0005730]; preribosome, large subunit precursor [GO:0030687]		ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]; translation initiation factor activity [GO:0003743]	amino acid binding [GO:0016597]; dimethylargininase activity [GO:0016403]; zinc ion binding [GO:0008270]
d1g63a__d4zawa___1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]	carboxy-lyase activity [GO:0016831]; flavin prenyltransferase activity [GO:0106141]; prenyltransferase activity [GO:0004659]; coenzyme biosynthetic process [GO:0009108]		coenzyme biosynthetic process [GO:0009108]			lyase activity [GO:0016829]	carboxy-lyase activity [GO:0016831]; flavin prenyltransferase activity [GO:0106141]; prenyltransferase activity [GO:0004659]
d1g63f__d3qjgc___1			Firmicutes	Firmicutes	lyase activity [GO:0016829]	catalytic activity [GO:0003824]; nucleotide binding [GO:0000166]					lyase activity [GO:0016829]	catalytic activity [GO:0003824]; nucleotide binding [GO:0000166]
d1g63i__d4rhee___1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]	flavin prenyltransferase activity [GO:0106141]; lyase activity [GO:0016829]; nucleotide binding [GO:0000166]; cofactor biosynthetic process [GO:0051188]		cofactor biosynthetic process [GO:0051188]			lyase activity [GO:0016829]	flavin prenyltransferase activity [GO:0106141]; lyase activity [GO:0016829]; nucleotide binding [GO:0000166]
d1g65d__d1pnl.1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	periplasmic space [GO:0042597]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]
d1g65l__d5l55n___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g65m__d2bpla3__1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	
d1g65t__d3wxra___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1g66a__d4yk7b___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; acetylxylan esterase activity [GO:0046555]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]		acetylxylan esterase activity [GO:0046555]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]
d1g6ea__d1amma1__1		Metazoa	Actinobacteria	Chordata		structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]
d1g6ja__d1oqya4__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; damaged DNA binding [GO:0003684]; kinase binding [GO:0019900]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; single-stranded DNA binding [GO:0003697]; ubiquitin binding [GO:0043130]; ubiquitin-specific protease binding [GO:1990381]; nucleotide-excision repair [GO:0006289]; positive regulation of cell cycle [GO:0045787]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of viral genome replication [GO:0045070]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; viral process [GO:0016032]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	nucleotide-excision repair [GO:0006289]; positive regulation of cell cycle [GO:0045787]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of viral genome replication [GO:0045070]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	damaged DNA binding [GO:0003684]; kinase binding [GO:0019900]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; single-stranded DNA binding [GO:0003697]; ubiquitin binding [GO:0043130]; ubiquitin-specific protease binding [GO:1990381]
d1g6kf__d3pqea1__1			Firmicutes	Firmicutes	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; sporulation resulting in formation of a cellular spore [GO:0030435]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	sporulation resulting in formation of a cellular spore [GO:0030435]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]	L-lactate dehydrogenase activity [GO:0004459]
d1g6kf__d4c7jb___1		Metazoa	Firmicutes	Chordata	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; sporulation resulting in formation of a cellular spore [GO:0030435]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	sporulation resulting in formation of a cellular spore [GO:0030435]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d1g6la1_d4y5na___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	aspartic-type endopeptidase activity [GO:0004190]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1g6la1_d5bryb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1g6la2_d1lyw.4__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	collagen-containing extracellular matrix [GO:0062023]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane raft [GO:0045121]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; aspartic-type endopeptidase activity [GO:0004190]; aspartic-type peptidase activity [GO:0070001]; peptidase activity [GO:0008233]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; collagen catabolic process [GO:0030574]; lipoprotein catabolic process [GO:0042159]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of establishment of protein localization [GO:0070201]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; collagen catabolic process [GO:0030574]; lipoprotein catabolic process [GO:0042159]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of establishment of protein localization [GO:0070201]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	collagen-containing extracellular matrix [GO:0062023]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane raft [GO:0045121]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; aspartic-type peptidase activity [GO:0070001]; peptidase activity [GO:0008233]
d1g6na2_d4d7sb___1			Proteobacteria	Spirochaetes	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	integral component of membrane [GO:0016021]; nucleotide binding [GO:0000166]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	integral component of membrane [GO:0016021]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	nucleotide binding [GO:0000166]
d1g6pa__d3a74a1__1			Thermotogae	Firmicutes	cytoplasm [GO:0005737]; DNA binding [GO:0003677]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]		lysyl-tRNA aminoacylation [GO:0006430]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d1g6q3__d2g70b___1	Fungi	Metazoa	Ascomycota	Chordata	nucleus [GO:0005634]; identical protein binding [GO:0042802]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; folic acid biosynthetic process [GO:0046656]; mRNA export from nucleus [GO:0006406]; negative regulation of DNA-templated transcription, termination [GO:0060567]; peptidyl-arginine methylation [GO:0018216]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	folic acid biosynthetic process [GO:0046656]; mRNA export from nucleus [GO:0006406]; negative regulation of DNA-templated transcription, termination [GO:0060567]; peptidyl-arginine methylation [GO:0018216]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d1g6rb1_d1j5ol1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1g6rc1_d1rv6x___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]
d1g6rc2_d4hk0d2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1g6rd2_d5d1ze1__1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]
d1g6rh1_d2ez0d1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1g6rh2_d1d5za2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d1g6rl__d4l3co2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1g6sa__d3slhd1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; 3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]	3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]
d1g6wa2_d2fchg___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1g6wb2_d3vwva1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; oxidation-reduction process [GO:0055114]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; protein maturation by protein folding [GO:0022417]; reactive oxygen species metabolic process [GO:0072593]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; oxidation-reduction process [GO:0055114]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; protein maturation by protein folding [GO:0022417]; reactive oxygen species metabolic process [GO:0072593]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; smooth endoplasmic reticulum [GO:0005790]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d1g6wd1_d2gdra2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	glutathione transferase activity [GO:0004364]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasm [GO:0005737]		glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	glutathione transferase activity [GO:0004364]
d1g6wd2_d6gsta2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d1g6ya2_d1xw9c___1	Fungi	Metazoa	Ascomycota	Arthropoda	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	cell [GO:0005623]; nucleus [GO:0005634]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]
d1g6yb2_d5a4wa1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d1g71a__d1rnia___1			Euryarchaeota	Crenarchaeota	primosome complex [GO:1990077]; DNA primase activity [GO:0003896]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]			primosome complex [GO:1990077]		DNA primase activity [GO:0003896]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1g71b__d1zt2a1__1			Euryarchaeota	Crenarchaeota	primosome complex [GO:1990077]; DNA primase activity [GO:0003896]; metal ion binding [GO:0046872]	primosome complex [GO:1990077]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA primase activity [GO:0003896]; metal ion binding [GO:0046872]			primosome complex [GO:1990077]	primosome complex [GO:1990077]	DNA primase activity [GO:0003896]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; DNA primase activity [GO:0003896]; metal ion binding [GO:0046872]
d1g72a__d4cvba___1			Proteobacteria		plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol oxidation [GO:0015946]	metal ion binding [GO:0046872]	methanol oxidation [GO:0015946]		plasma membrane [GO:0005886]		2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]	metal ion binding [GO:0046872]
d1g72c__d4maea___1			Proteobacteria	Verrucomicrobia	plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol oxidation [GO:0015946]	membrane [GO:0016020]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; ethanol:cytochrome c oxidoreductase activity [GO:0052935]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]	methanol oxidation [GO:0015946]		plasma membrane [GO:0005886]	membrane [GO:0016020]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol:cytochrome c oxidoreductase activity [GO:0052935]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]
d1g74a__d4zhfe___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1g7ca2_d4h9ga3__1	Fungi		Ascomycota	Deinococcus-Thermus	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]		cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]	cytoplasm [GO:0005737]	guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1g7ha__d1im3m1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1g7hb__d4r7dj1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1g7ia__d1i9rh1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]; activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]
d1g7ja__d1p4bl___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1g7jc__d1nwga___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1g7mb__d1hi6b2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1g7oa1_d4ri7b2__1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; glutathione oxidoreductase activity [GO:0097573]; cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; glutathione oxidoreductase activity [GO:0097573]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1g7pa1_d4wi9a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1g7pb__d1t03l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1g7qa1_d1fvda1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1g7qb__d5mwne1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1g7wa__d1pffa___1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]; carbon-sulfur lyase activity [GO:0016846]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	carbon-sulfur lyase activity [GO:0016846]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d1g82a__d1hknc___1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; embryonic digestive tract development [GO:0048566]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inner ear morphogenesis [GO:0042472]; lung-associated mesenchyme development [GO:0060484]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; MAPK cascade [GO:0000165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein import into nucleus [GO:0006606]; regulation of timing of cell differentiation [GO:0048505]; signal transduction [GO:0007165]; substantia nigra development [GO:0021762]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; embryonic digestive tract development [GO:0048566]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inner ear morphogenesis [GO:0042472]; lung-associated mesenchyme development [GO:0060484]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; MAPK cascade [GO:0000165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein import into nucleus [GO:0006606]; regulation of timing of cell differentiation [GO:0048505]; signal transduction [GO:0007165]; substantia nigra development [GO:0021762]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	basement membrane [GO:0005604]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1g82c__d1ii4a___1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; embryonic digestive tract development [GO:0048566]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inner ear morphogenesis [GO:0042472]; lung-associated mesenchyme development [GO:0060484]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; MAPK cascade [GO:0000165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein import into nucleus [GO:0006606]; regulation of timing of cell differentiation [GO:0048505]; signal transduction [GO:0007165]; substantia nigra development [GO:0021762]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; embryonic digestive tract development [GO:0048566]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inner ear morphogenesis [GO:0042472]; lung-associated mesenchyme development [GO:0060484]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; MAPK cascade [GO:0000165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein import into nucleus [GO:0006606]; regulation of timing of cell differentiation [GO:0048505]; signal transduction [GO:0007165]; substantia nigra development [GO:0021762]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	basement membrane [GO:0005604]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1g82c__d1twea___1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; embryonic digestive tract development [GO:0048566]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inner ear morphogenesis [GO:0042472]; lung-associated mesenchyme development [GO:0060484]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; MAPK cascade [GO:0000165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein import into nucleus [GO:0006606]; regulation of timing of cell differentiation [GO:0048505]; signal transduction [GO:0007165]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; embryonic digestive tract development [GO:0048566]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inner ear morphogenesis [GO:0042472]; lung-associated mesenchyme development [GO:0060484]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; MAPK cascade [GO:0000165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein import into nucleus [GO:0006606]; regulation of timing of cell differentiation [GO:0048505]; signal transduction [GO:0007165]; substantia nigra development [GO:0021762]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	basement membrane [GO:0005604]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d1g85a__d1opaa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol metabolic process [GO:0042572]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	retinol metabolic process [GO:0042572]	extracellular region [GO:0005576]	cytosol [GO:0005829]	small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinol binding [GO:0019841]
d1g85b__d3tgaa___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	vasodilation [GO:0042311]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	small molecule binding [GO:0036094]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d1g86a__d3b00d___1	Metazoa		Chordata	Thermotogae	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; carbohydrate binding [GO:0030246]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; identical protein binding [GO:0042802]; multicellular organism development [GO:0007275]; regulation of activated T cell proliferation [GO:0046006]; regulation of T cell anergy [GO:0002667]; regulation of T cell cytokine production [GO:0002724]; T cell apoptotic process [GO:0070231]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	multicellular organism development [GO:0007275]; regulation of activated T cell proliferation [GO:0046006]; regulation of T cell anergy [GO:0002667]; regulation of T cell cytokine production [GO:0002724]; T cell apoptotic process [GO:0070231]	carbohydrate metabolic process [GO:0005975]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]		carbohydrate binding [GO:0030246]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; identical protein binding [GO:0042802]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1g87a1_d2d8la___1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cytoplasm [GO:0005737]; unsaturated rhamnogalacturonyl hydrolase activity [GO:0102211]; metabolic process [GO:0008152]	cellulose catabolic process [GO:0030245]	metabolic process [GO:0008152]		cytoplasm [GO:0005737]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	unsaturated rhamnogalacturonyl hydrolase activity [GO:0102211]
d1g87b2_d3p0db___1			Firmicutes		cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]				cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	
d1g87b2_d3zqxa1__1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d1g8ga3_d3l0ob2__1	Fungi		Ascomycota	Thermotogae	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	DNA-templated transcription, termination [GO:0006353]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]
d1g8gb1_d4mafh1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	nucleotide binding [GO:0000166]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	nucleotide binding [GO:0000166]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1g8gb2_d1ihoa___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantoate-beta-alanine ligase activity [GO:0004592]; pantothenate biosynthetic process from valine [GO:0033317]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	pantothenate biosynthetic process from valine [GO:0033317]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantoate-beta-alanine ligase activity [GO:0004592]
d1g8gb3_d1e0je___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d1g8gb3_d1m8pa3__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1g8ha2_d3q10a1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cytosol [GO:0005829]; ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]; pantothenate biosynthetic process from valine [GO:0033317]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	pantothenate biosynthetic process from valine [GO:0033317]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]
d1g8ka1_d1fdoa1__1			Proteobacteria	Proteobacteria	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	cytosol [GO:0005829]; plasma membrane respiratory chain complex I [GO:0045272]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (NAD+) activity [GO:0008863]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; formate oxidation [GO:0015944]		formate oxidation [GO:0015944]		cytosol [GO:0005829]; plasma membrane respiratory chain complex I [GO:0045272]	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (NAD+) activity [GO:0008863]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]
d1g8kb__d1uljc1__1			Proteobacteria	Actinobacteria	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1g8kc2_d1ti4i2__1			Proteobacteria		3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]						3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	
d1g8ke1_d2jioa1__1			Proteobacteria	Proteobacteria	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]		Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]
d1g8kg1_d1h5nc1__1			Proteobacteria	Proteobacteria	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]				periplasmic space [GO:0042597]	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]
d1g8ra3_d3mcib___1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	
d1g8wa__d5nbpa___1	Viridiplantae		Streptophyta	Bacteroidetes	mannose binding [GO:0005537]; toxin activity [GO:0090729]; defense response [GO:0006952]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	defense response [GO:0006952]	carbohydrate metabolic process [GO:0005975]			mannose binding [GO:0005537]; toxin activity [GO:0090729]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1g8wb__d1reeb1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	mannose binding [GO:0005537]; toxin activity [GO:0090729]; defense response [GO:0006952]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	defense response [GO:0006952]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	mannose binding [GO:0005537]; toxin activity [GO:0090729]	endo-1,4-beta-xylanase activity [GO:0031176]
d1g8zd__d1rd9e___1			Proteobacteria	Proteobacteria	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d1g8ze__d1an8a1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1g8zg__d1bova___1			Proteobacteria		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]		galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	
d1g95a1_d1kk5e___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	transferase activity, transferring acyl groups [GO:0016746]
d1g97a1_d4e6tc___1			Firmicutes		cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	
d1g97a2_d4ho9a___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	extracellular polysaccharide biosynthetic process [GO:0045226]	cytoplasm [GO:0005737]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1g98a__d2cxsb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d1g98b__d2cxrb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d1g99b1_d2e20a1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]; L-threonine catabolic process to propionate [GO:0070689]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	L-threonine catabolic process to propionate [GO:0070689]	cytoplasm [GO:0005737]		acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]
d1g99b2_d4fwpa2__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]; L-threonine catabolic process to propionate [GO:0070689]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	L-threonine catabolic process to propionate [GO:0070689]	cytoplasm [GO:0005737]		acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]
d1g9da2_d3azwb2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]	negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]
d1g9da3_d1fbla2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular matrix [GO:0031012]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; extracellular matrix organization [GO:0030198]	negative regulation of neurotransmitter secretion [GO:0046929]	collagen catabolic process [GO:0030574]; extracellular matrix organization [GO:0030198]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular matrix [GO:0031012]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1g9ea1_d4jfyl1__1												
d1g9ha2_d1n82a___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d1g9ja__d1ulva1__1			Firmicutes	Actinobacteria	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]; polysaccharide metabolic process [GO:0005976]	cellulose catabolic process [GO:0030245]	polysaccharide metabolic process [GO:0005976]			cellulase activity [GO:0008810]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]
d1g9mh1_d1u92a2__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1g9ml2_d1bqhh___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1g9nh1_d3sy0a1__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1g9ua__d3c09d1__1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	metal ion binding [GO:0046872]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d1g9ya__d2i3pa___1	Viridiplantae	Viridiplantae	Chlorophyta	Chlorophyta	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]	intron homing [GO:0006314]	intron homing [GO:0006314]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1g9zb__d2vbob___1	Viridiplantae	Viridiplantae	Chlorophyta	Chlorophyta	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]	intron homing [GO:0006314]	intron homing [GO:0006314]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1ga1a__d1siua___1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]			periplasmic space [GO:0042597]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1ga2b1_d2xfga1__1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]
d1ga3a1_d2b8ya___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]; activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]
d1ga6a__d1gt92___1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]			periplasmic space [GO:0042597]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1ga7b__d5ghjb___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ADP-ribose diphosphatase activity [GO:0047631]; ADP-sugar diphosphatase activity [GO:0019144]; magnesium ion binding [GO:0000287]; nucleoside phosphate metabolic process [GO:0006753]; response to heat [GO:0009408]; ribose phosphate metabolic process [GO:0019693]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTP diphosphatase activity [GO:0036219]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]; aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	nucleoside phosphate metabolic process [GO:0006753]; response to heat [GO:0009408]; ribose phosphate metabolic process [GO:0019693]	aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ADP-ribose diphosphatase activity [GO:0047631]; ADP-sugar diphosphatase activity [GO:0019144]; magnesium ion binding [GO:0000287]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTPase activity [GO:0003924]; GTP diphosphatase activity [GO:0036219]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]
d1gaeo2_d1pqua2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	cytosol [GO:0005829]; membrane [GO:0016020]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]
d1gafh1_d1qlrd1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1gafh1_d4hafa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1gafl2_d2dlta1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytoskeleton [GO:0005856]; myosin filament [GO:0032982]; actin binding [GO:0003779]; structural constituent of cytoskeleton [GO:0005200]; cell adhesion [GO:0007155]; muscle contraction [GO:0006936]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell adhesion [GO:0007155]; muscle contraction [GO:0006936]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytoskeleton [GO:0005856]; myosin filament [GO:0032982]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin binding [GO:0003779]; structural constituent of cytoskeleton [GO:0005200]
d1gaka__d2lync___1	Metazoa	Metazoa	Mollusca	Mollusca	single fertilization [GO:0007338]	acrosomal lumen [GO:0043160]; single fertilization [GO:0007338]	single fertilization [GO:0007338]	single fertilization [GO:0007338]		acrosomal lumen [GO:0043160]		
d1gama__d1ag4a___1	Metazoa		Chordata		structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; membrane [GO:0016020]; cell-cell adhesion [GO:0098609]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	cell-cell adhesion [GO:0098609]		cytoplasm [GO:0005737]; membrane [GO:0016020]	structural constituent of eye lens [GO:0005212]	
d1gama__d3hzbf___1	Metazoa		Chordata	Bacteroidetes	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1gamb__d2v2ua2__1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; camera-type eye development [GO:0043010]; eye development [GO:0001654]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	camera-type eye development [GO:0043010]; eye development [GO:0001654]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d1ganb__d2cnaa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]			extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1gaqa1_d3fpkb1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]		chloroplast thylakoid membrane protein complex [GO:0098807]	cytosol [GO:0005829]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1gaqa2_d3fpkb2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]		chloroplast thylakoid membrane protein complex [GO:0098807]	cytosol [GO:0005829]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1gaqc2_d5h59a2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]		chloroplast thylakoid membrane protein complex [GO:0098807]	chloroplast [GO:0009507]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1gav5__d2bu1c___1					T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1gav9__d2bnyb___1					T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1gavd__d1frsa___1					T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1gavj__d1aq3c___1					T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1gavl__d7msfa___1					T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1gavu__d2iz8c1__1					T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1gawa1_d1ndha1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	cholesterol biosynthetic process [GO:0006695]	chloroplast thylakoid membrane protein complex [GO:0098807]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1gawa2_d3ojxa3__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	chloroplast thylakoid membrane protein complex [GO:0098807]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1gawb2_d3ozua3__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	chloroplast thylakoid membrane protein complex [GO:0098807]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1gaxb4_d1sesa1__1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; valine-tRNA ligase activity [GO:0004832]; valyl-tRNA aminoacylation [GO:0006438]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; serine binding [GO:0070905]; serine-tRNA ligase activity [GO:0004828]; tRNA binding [GO:0000049]; selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	valyl-tRNA aminoacylation [GO:0006438]	selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; valine-tRNA ligase activity [GO:0004832]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; serine binding [GO:0070905]; serine-tRNA ligase activity [GO:0004828]; tRNA binding [GO:0000049]
d1gaxb5_d1pfva1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; valine-tRNA ligase activity [GO:0004832]; valyl-tRNA aminoacylation [GO:0006438]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; methionyl-tRNA aminoacylation [GO:0006431]	valyl-tRNA aminoacylation [GO:0006438]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; valine-tRNA ligase activity [GO:0004832]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1gaya__d1bb4a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1gaza__d2ntha___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gb0a__d184la___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gb3a__d5lioa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1gb6a__d219la___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gb7a__d165la___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gbaa__d4dg4b___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]		negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]
d1gbba__d1utpa___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1gbda__d1dt2a___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]			extracellular region [GO:0005576]		serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]
d1gbda__d2w7uc___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1gbea__d2wpks___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]		blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]
d1gbia__d2w26a___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1gbka__d1rtf.1__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	apical part of cell [GO:0045177]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; phosphoprotein binding [GO:0051219]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; blood coagulation [GO:0007596]; cellular protein modification process [GO:0006464]; fibrinolysis [GO:0042730]; negative regulation of proteolysis [GO:0045861]; plasminogen activation [GO:0031639]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; proteolysis [GO:0006508]; response to hypoxia [GO:0001666]; smooth muscle cell migration [GO:0014909]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]		blood coagulation [GO:0007596]; cellular protein modification process [GO:0006464]; fibrinolysis [GO:0042730]; negative regulation of proteolysis [GO:0045861]; plasminogen activation [GO:0031639]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; proteolysis [GO:0006508]; response to hypoxia [GO:0001666]; smooth muscle cell migration [GO:0014909]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]	extracellular region [GO:0005576]	apical part of cell [GO:0045177]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]	serine-type endopeptidase activity [GO:0004252]	phosphoprotein binding [GO:0051219]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d1gboa__d1qt7a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gbua__d1cg5a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1gbua__d2d2ma___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1gbva__d2uunu___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1gbvc__d4pqca___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1gbvd__d5fvbc___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1gbwa__d1qswa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1gbxa__d4ddba___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1gc1c1_d4pv9a2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1gc1c2_d5mzab2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]
d1gc1h1_d1tvha1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1gc1h2_d2jk5a1__1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	voltage-gated potassium channel complex [GO:0008076]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1gc1h2_d2p5eb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytoplasm [GO:0005737]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1gc1l1_d1wioa1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1gc1l2_d1a6vj___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1gc3a__d3vaxb___1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	catalytic activity [GO:0003824]	biosynthetic process [GO:0009058]		cytoplasm [GO:0005737]		aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]	catalytic activity [GO:0003824]
d1gc3a__d3wzfa___1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; carboxylic acid binding [GO:0031406]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; phosphatidylserine decarboxylase activity [GO:0004609]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; fatty acid homeostasis [GO:0055089]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of mitochondrial depolarization [GO:0051902]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; response to cadmium ion [GO:0046686]; response to carbohydrate [GO:0009743]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to transition metal nanoparticle [GO:1990267]; transdifferentiation [GO:0060290]	biosynthetic process [GO:0009058]	2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; fatty acid homeostasis [GO:0055089]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of mitochondrial depolarization [GO:0051902]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; response to cadmium ion [GO:0046686]; response to carbohydrate [GO:0009743]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to transition metal nanoparticle [GO:1990267]; transdifferentiation [GO:0060290]	cytoplasm [GO:0005737]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]	carboxylic acid binding [GO:0031406]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; phosphatidylserine decarboxylase activity [GO:0004609]; pyridoxal phosphate binding [GO:0030170]
d1gc4a__d3fqab___1			Deinococcus-Thermus	Cyanobacteria	cytoplasm [GO:0005737]; aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	biosynthetic process [GO:0009058]	chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1gc4c__d5dx5b___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	biosynthetic process [GO:0009058]	transsulfuration [GO:0019346]	cytoplasm [GO:0005737]		aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d1gc5a__d3b1na___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; ADP-specific glucokinase activity [GO:0043843]; glucokinase activity [GO:0004340]; magnesium ion binding [GO:0000287]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	kinase activity [GO:0016301]; nucleotide binding [GO:0000166]; phosphotransferase activity, alcohol group as acceptor [GO:0016773]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		ADP-specific glucokinase activity [GO:0043843]; glucokinase activity [GO:0004340]; magnesium ion binding [GO:0000287]	kinase activity [GO:0016301]; nucleotide binding [GO:0000166]; phosphotransferase activity, alcohol group as acceptor [GO:0016773]
d1gc6a1_d3wa0d2__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d1gc6a3_d1e5wa3__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; invadopodium [GO:0071437]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; cell adhesion molecule binding [GO:0050839]; double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]; cellular response to testosterone stimulus [GO:0071394]; establishment of endothelial barrier [GO:0061028]; establishment of epithelial cell apical/basal polarity [GO:0045198]; gland morphogenesis [GO:0022612]; immunological synapse formation [GO:0001771]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein localization to early endosome [GO:1902966]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of lymphocyte migration [GO:2000401]; regulation of organelle assembly [GO:1902115]; T cell aggregation [GO:0070489]; T cell migration [GO:0072678]; T cell proliferation [GO:0042098]; viral process [GO:0016032]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cellular response to testosterone stimulus [GO:0071394]; establishment of endothelial barrier [GO:0061028]; establishment of epithelial cell apical/basal polarity [GO:0045198]; gland morphogenesis [GO:0022612]; immunological synapse formation [GO:0001771]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein localization to early endosome [GO:1902966]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of lymphocyte migration [GO:2000401]; regulation of organelle assembly [GO:1902115]; T cell aggregation [GO:0070489]; T cell migration [GO:0072678]; T cell proliferation [GO:0042098]; viral process [GO:0016032]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; invadopodium [GO:0071437]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; uropod [GO:0001931]; vesicle [GO:0031982]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; cell adhesion molecule binding [GO:0050839]; double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]
d1gc7a1_d4ny0d2__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]
d1gc7a3_d4dhjh___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1gc8a__d1cm7b___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	cytosol [GO:0005829]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; cellular response to amino acid starvation [GO:0034198]; leucine biosynthetic process [GO:0009098]	leucine biosynthetic process [GO:0009098]	cellular response to amino acid starvation [GO:0034198]; leucine biosynthetic process [GO:0009098]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]
d1gc8b__d5hn4a___1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	mitochondrion [GO:0005739]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; homoisocitrate dehydrogenase activity [GO:0047046]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]; lysine biosynthetic process [GO:0009085]	leucine biosynthetic process [GO:0009098]	leucine biosynthetic process [GO:0009098]; lysine biosynthetic process [GO:0009085]	cytoplasm [GO:0005737]	mitochondrion [GO:0005739]	3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	3-isopropylmalate dehydrogenase activity [GO:0003862]; homoisocitrate dehydrogenase activity [GO:0047046]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1gcfa__d3uyod___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; granulocyte colony-stimulating factor binding [GO:0051916]; amelogenesis [GO:0097186]; cell adhesion [GO:0007155]; neutrophil chemotaxis [GO:0030593]; regulation of myeloid cell differentiation [GO:0045637]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	amelogenesis [GO:0097186]; cell adhesion [GO:0007155]; neutrophil chemotaxis [GO:0030593]; regulation of myeloid cell differentiation [GO:0045637]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; receptor complex [GO:0043235]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; granulocyte colony-stimulating factor binding [GO:0051916]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]
d1gckb__d2w7ma___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	biosynthetic process [GO:0009058]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]
d1gcob__d5bshj1__1		Viridiplantae	Firmicutes	Streptophyta	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; sporulation resulting in formation of a cellular spore [GO:0030435]	cell wall [GO:0005618]; nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]; L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]	sporulation resulting in formation of a cellular spore [GO:0030435]	L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]		cell wall [GO:0005618]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]	nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1gcoe__d3k92c2__1			Firmicutes	Firmicutes	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; sporulation resulting in formation of a cellular spore [GO:0030435]	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	sporulation resulting in formation of a cellular spore [GO:0030435]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]			glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]	glutamate dehydrogenase (NAD+) activity [GO:0004352]
d1gcof__d1ch6f2__1			Firmicutes		glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]				glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]	
d1gcsa2_d3i9hf___1	Metazoa		Chordata	Firmicutes	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1gcvc__d2uunf___1	Metazoa		Chordata		hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1gcza1_d4pkzb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d1gd7d__d1pyba___1			Deinococcus-Thermus	Aquificae	tRNA binding [GO:0000049]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; methionyl-tRNA aminoacylation [GO:0006431]		methionyl-tRNA aminoacylation [GO:0006431]			tRNA binding [GO:0000049]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]
d1gd8b__d2qoxn1__1			Deinococcus-Thermus		ribosome [GO:0005840]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		structural constituent of ribosome [GO:0003735]	
d1gd8c__d2z4nn1__1			Deinococcus-Thermus		ribosome [GO:0005840]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		structural constituent of ribosome [GO:0003735]	
d1gd8f__d2qbin1__1			Deinococcus-Thermus		ribosome [GO:0005840]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		structural constituent of ribosome [GO:0003735]	
d1gdea__d3zzka___1			Euryarchaeota	Proteobacteria	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	biosynthetic process [GO:0009058]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1gdfa__d1ji1a1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]	extracellular region [GO:0005576]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1gdha1_d2cfcb___1			Proteobacteria	Proteobacteria	glycerate dehydrogenase activity [GO:0008465]; NAD binding [GO:0051287]	2-(R)-hydroxypropyl-CoM dehydrogenase activity [GO:0050574]; propylene catabolic process [GO:0042208]		propylene catabolic process [GO:0042208]			glycerate dehydrogenase activity [GO:0008465]; NAD binding [GO:0051287]	2-(R)-hydroxypropyl-CoM dehydrogenase activity [GO:0050574]
d1gdia__d3a0ga___1	Viridiplantae	Metazoa	Streptophyta	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1gdka__d1ygdd___1	Viridiplantae	Metazoa	Streptophyta	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1gdla__d4h0ma___1	Viridiplantae		Streptophyta	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1gdoc__d1q19c2__1				Proteobacteria		asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]; antibiotic biosynthetic process [GO:0017000]; asparagine biosynthetic process [GO:0006529]		antibiotic biosynthetic process [GO:0017000]; asparagine biosynthetic process [GO:0006529]				asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]
d1gdta2_d3pkza___1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]; transposition [GO:0032196]	DNA integration [GO:0015074]	DNA integration [GO:0015074]; transposition [GO:0032196]			DNA binding [GO:0003677]; recombinase activity [GO:0000150]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]
d1gdva__d3h1hd1__1		Metazoa	Rhodophyta	Chordata	chloroplast thylakoid lumen [GO:0009543]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	photosynthesis [GO:0015979]		chloroplast thylakoid lumen [GO:0009543]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1gdva__d451ca___1			Rhodophyta	Proteobacteria	chloroplast thylakoid lumen [GO:0009543]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	photosynthesis [GO:0015979]		chloroplast thylakoid lumen [GO:0009543]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1gdwa__d2h5za___1	Metazoa	Metazoa	Chordata	Arthropoda	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	lysozyme activity [GO:0003796]; metabolic process [GO:0008152]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	metabolic process [GO:0008152]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ge3a__d3cdva___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ge4a__d5kxsa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1gece__d4qbbc___1	Viridiplantae		Streptophyta		cysteine-type peptidase activity [GO:0008234]	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cysteine-type peptidase activity [GO:0008234]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1gece__d5tuna___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cysteine-type peptidase activity [GO:0008234]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]		autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]		endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	cysteine-type peptidase activity [GO:0008234]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d1geeb__d3t7cb___1			Firmicutes	Actinobacteria	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; sporulation resulting in formation of a cellular spore [GO:0030435]	(+)-trans-carveol dehydrogenase activity [GO:0033702]; nucleotide binding [GO:0000166]	sporulation resulting in formation of a cellular spore [GO:0030435]				glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]	(+)-trans-carveol dehydrogenase activity [GO:0033702]; nucleotide binding [GO:0000166]
d1geee__d1dhta___1		Metazoa	Firmicutes	Chordata	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; sporulation resulting in formation of a cellular spore [GO:0030435]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]; estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	sporulation resulting in formation of a cellular spore [GO:0030435]	estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]	catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]
d1gega__d3i3oa___1			Proteobacteria	Firmicutes	diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; acetoin catabolic process [GO:0045150]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	acetoin catabolic process [GO:0045150]				diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1gegc__d3nugd___1			Proteobacteria	Proteobacteria	diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; acetoin catabolic process [GO:0045150]	pyridoxal 4-dehydrogenase activity [GO:0050235]; vitamin B6 catabolic process [GO:0042820]	acetoin catabolic process [GO:0045150]	vitamin B6 catabolic process [GO:0042820]			diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]	pyridoxal 4-dehydrogenase activity [GO:0050235]
d1gegd__d4u6sa2__1		Metazoa	Proteobacteria	Chordata	diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; acetoin catabolic process [GO:0045150]	GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; presynaptic active zone cytoplasmic component [GO:0098831]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; chromatin silencing [GO:0006342]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H4 acetylation [GO:0090241]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of histone deacetylation [GO:0031065]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; viral genome replication [GO:0019079]; white fat cell differentiation [GO:0050872]	acetoin catabolic process [GO:0045150]	chromatin silencing [GO:0006342]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H4 acetylation [GO:0090241]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; viral genome replication [GO:0019079]; white fat cell differentiation [GO:0050872]		GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; presynaptic active zone cytoplasmic component [GO:0098831]; transcriptional repressor complex [GO:0017053]	diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]	chromatin binding [GO:0003682]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]
d1gegg__d2cfca___1			Proteobacteria	Proteobacteria	diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; acetoin catabolic process [GO:0045150]	2-(R)-hydroxypropyl-CoM dehydrogenase activity [GO:0050574]; propylene catabolic process [GO:0042208]	acetoin catabolic process [GO:0045150]	propylene catabolic process [GO:0042208]			diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]	2-(R)-hydroxypropyl-CoM dehydrogenase activity [GO:0050574]
d1gegh__d2jkvb1__1		Metazoa	Proteobacteria	Chordata	diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; acetoin catabolic process [GO:0045150]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate catabolic process [GO:0046177]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	acetoin catabolic process [GO:0045150]	D-gluconate catabolic process [GO:0046177]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]
d1geja__d1re9a___1	Fungi		Ascomycota	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1geka__d5dqna___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; cholesterol catabolic process [GO:0006707]	(+)-camphor catabolic process [GO:0019383]	cholesterol catabolic process [GO:0006707]	cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1gesb3_d1ebda3__1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]	glycolytic process [GO:0006096]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]
d1geta3_d1mokb3__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; 2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]	2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]
d1geza__d1l12a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gf0a__d183la___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gf5a__d1l44a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gf5a__d1op9b___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1gf6a__d1ja2a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1gf9a__d1l06a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gf9a__d5i4xa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1gfaa__d1l58a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gfea__d4yf2c___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	acrosomal matrix [GO:0043159]; acrosomal membrane [GO:0002080]; acrosomal vesicle [GO:0001669]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; secretory granule [GO:0030141]; lysozyme activity [GO:0003796]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; sperm-egg recognition [GO:0035036]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; sperm-egg recognition [GO:0035036]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	acrosomal matrix [GO:0043159]; acrosomal membrane [GO:0002080]; acrosomal vesicle [GO:0001669]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; secretory granule [GO:0030141]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gff2__d1al0g___1					host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]; DNA binding [GO:0003677]	host cell cytoplasm [GO:0030430]; viral procapsid maturation [GO:0046797]		viral procapsid maturation [GO:0046797]	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]	host cell cytoplasm [GO:0030430]	DNA binding [GO:0003677]	
d1gfga__d1lmca___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gfja__d5kxxa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1gfka__d5k2ka___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1gfta__d1lmoa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gfva__d5hnca___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1gfya__d5tsra___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; prenylated protein tyrosine phosphatase activity [GO:0004727]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cellular response to leukemia inhibitory factor [GO:1990830]; endothelial cell migration [GO:0043542]; Notch signaling pathway [GO:0007219]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of vascular permeability [GO:0043117]; regulation of transcription, DNA-templated [GO:0006355]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cellular response to leukemia inhibitory factor [GO:1990830]; endothelial cell migration [GO:0043542]; Notch signaling pathway [GO:0007219]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of vascular permeability [GO:0043117]; regulation of transcription, DNA-templated [GO:0006355]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	prenylated protein tyrosine phosphatase activity [GO:0004727]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1gg3a3_d4k7wc___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1gg3b1_d2emta1__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d1gg3b2_d1mizb2__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]
d1gg3b3_d2d10d3__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d1gg3c1_d4zrkd2__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d1gg3c2_d1h4ra2__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]	actin binding [GO:0003779]
d1gg3c3_d4ksld2__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1gg5a__d1ycfc1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1gg5c__d2zkia___1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]
d1gg5d__d1h69c___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d1ggbl1_d1reib___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]
d1ggbl1_d3qehb1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ggbl2_d4ogyl1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ggch2_d3mugk1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ggcl1_d2f53d1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	cytoplasm [GO:0005737]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ggcl2_d1s8da1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ggcl2_d5x8ld___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ggeb1_d1t0be___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	metal ion binding [GO:0046872]
d1ggec1_d2auma2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; carboxypeptidase activity [GO:0004180]; serine-type peptidase activity [GO:0008236]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	carboxypeptidase activity [GO:0004180]; serine-type peptidase activity [GO:0008236]
d1ggga__d4p0ib___1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; ligand-gated ion channel activity [GO:0015276]; amino acid transport [GO:0006865]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	amino acid transport [GO:0006865]	nitrogen compound transport [GO:0071705]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	ligand-gated ion channel activity [GO:0015276]	ligand-gated ion channel activity [GO:0015276]
d1gghd1_d4k2hk___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; peptidase activity [GO:0008233]; protein deglycase activity [GO:0036524]; guanine deglycation, glyoxal removal [GO:0106046]; protein deglycation, glyoxal removal [GO:0036529]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	guanine deglycation, glyoxal removal [GO:0106046]; protein deglycation, glyoxal removal [GO:0036529]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	metal ion binding [GO:0046872]; peptidase activity [GO:0008233]; protein deglycase activity [GO:0036524]
d1ggij1_d2z92b1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ggij2_d2gkia1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ggil1_d2i5yh1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ggil2_d5e5ma___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ggim2_d4jy5l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ggjc1_d4ofwf1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; glyoxalase III activity [GO:0019172]; lactoylglutathione lyase activity [GO:0004462]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	glyoxalase III activity [GO:0019172]; lactoylglutathione lyase activity [GO:0004462]
d1ggkb1_d1sy7a1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	ascospore wall [GO:0005619]; cytosol [GO:0005829]; extracellular region [GO:0005576]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; conidium formation [GO:0048315]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	conidium formation [GO:0048315]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ascospore wall [GO:0005619]; cytosol [GO:0005829]; extracellular region [GO:0005576]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1ggkd1_d2ck9b___1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]		cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	
d1ggla__d3dsza___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]		antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1ggoa2_d2fm4a___1			Firmicutes	Firmicutes	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]	pyruvate metabolic process [GO:0006090]	pyruvate metabolic process [GO:0006090]			ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]
d1ggpa__d1ahaa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1ggpa__d3ku0b___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1ggpb2_d2drzb___1	Viridiplantae	Metazoa	Streptophyta	Annelida	rRNA N-glycosylase activity [GO:0030598]; negative regulation of translation [GO:0017148]	carbohydrate binding [GO:0030246]	negative regulation of translation [GO:0017148]				rRNA N-glycosylase activity [GO:0030598]	carbohydrate binding [GO:0030246]
d1ggpb2_d3ca5a1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; negative regulation of translation [GO:0017148]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1ggqc__d1yjge___1			Spirochaetes	Spirochaetes	external side of cell outer membrane [GO:0031240]; membrane [GO:0016020]	cell outer membrane [GO:0009279]			external side of cell outer membrane [GO:0031240]; membrane [GO:0016020]	cell outer membrane [GO:0009279]		
d1ggta2_d4ktyb4__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1ggta4_d2f4oa2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]; glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	metal ion binding [GO:0046872]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]
d1ggub2_d1nuda2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]
d1ggub3_d1rllb4__1	Metazoa		Chordata		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]		blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]		metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	
d1ggub4_d3kwza___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d1ggwa__d1uwob___1	Fungi	Metazoa	Ascomycota	Chordata	actomyosin contractile ring [GO:0005826]; cell division site [GO:0032153]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; medial cortical node [GO:0071341]; mitotic actomyosin contractile ring [GO:0110085]; myosin II complex [GO:0016460]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; division septum assembly [GO:0000917]; mitotic actomyosin contractile ring assembly [GO:1903475]; mitotic actomyosin contractile ring assembly actin filament organization [GO:1903479]; protein localization to medial cortex [GO:0071574]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	division septum assembly [GO:0000917]; mitotic actomyosin contractile ring assembly [GO:1903475]; mitotic actomyosin contractile ring assembly actin filament organization [GO:1903479]; protein localization to medial cortex [GO:0071574]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	actomyosin contractile ring [GO:0005826]; cell division site [GO:0032153]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; medial cortical node [GO:0071341]; mitotic actomyosin contractile ring [GO:0110085]; myosin II complex [GO:0016460]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	metal ion binding [GO:0046872]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1ggya2_d1l9na2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]
d1ggza__d1fi6a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; calcium ion binding [GO:0005509]; calcium-mediated signaling [GO:0019722]	clathrin-coated pit [GO:0005905]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; SH3 domain binding [GO:0017124]; receptor-mediated endocytosis [GO:0006898]	calcium-mediated signaling [GO:0019722]	receptor-mediated endocytosis [GO:0006898]	extracellular exosome [GO:0070062]	clathrin-coated pit [GO:0005905]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; SH3 domain binding [GO:0017124]
d1gh0k__d5ksid___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1gh0w__d3gqrc___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	phycobilisome [GO:0030089]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1gh4a__d1m8tc___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1gh5a__d1a5da2__1		Metazoa	Actinobacteria	Chordata		structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]
d1gh7b2_d1uc6a1__1	Metazoa	Metazoa	Chordata	Chordata	granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; signaling receptor activity [GO:0038023]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-3 [GO:0036016]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-3-mediated signaling pathway [GO:0038156]; interleukin-5-mediated signaling pathway [GO:0038043]; MAPK cascade [GO:0000165]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]	anchored component of membrane [GO:0031225]; apical plasma membrane [GO:0016324]; ciliary neurotrophic factor receptor complex [GO:0070110]; CNTFR-CLCF1 complex [GO:0097059]; external side of plasma membrane [GO:0009897]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor receptor activity [GO:0004897]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; signaling receptor binding [GO:0005102]; brainstem development [GO:0003360]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; positive regulation of cell population proliferation [GO:0008284]; sex differentiation [GO:0007548]; signal transduction [GO:0007165]; skeletal muscle organ development [GO:0060538]; suckling behavior [GO:0001967]	cellular protein metabolic process [GO:0044267]; cellular response to interleukin-3 [GO:0036016]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-3-mediated signaling pathway [GO:0038156]; interleukin-5-mediated signaling pathway [GO:0038043]; MAPK cascade [GO:0000165]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]	brainstem development [GO:0003360]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; positive regulation of cell population proliferation [GO:0008284]; sex differentiation [GO:0007548]; signal transduction [GO:0007165]; skeletal muscle organ development [GO:0060538]; suckling behavior [GO:0001967]	granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	anchored component of membrane [GO:0031225]; apical plasma membrane [GO:0016324]; ciliary neurotrophic factor receptor complex [GO:0070110]; CNTFR-CLCF1 complex [GO:0097059]; external side of plasma membrane [GO:0009897]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytokine receptor activity [GO:0004896]; signaling receptor activity [GO:0038023]	ciliary neurotrophic factor receptor activity [GO:0004897]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; signaling receptor binding [GO:0005102]
d1gh7b4_d1y6mr2__1	Metazoa	Metazoa	Chordata	Chordata	granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; signaling receptor activity [GO:0038023]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-3 [GO:0036016]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-3-mediated signaling pathway [GO:0038156]; interleukin-5-mediated signaling pathway [GO:0038043]; MAPK cascade [GO:0000165]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; interleukin-10 binding [GO:0019969]; interleukin-10 receptor activity [GO:0004920]; signaling receptor activity [GO:0038023]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of autophagy [GO:0010507]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of synapse organization [GO:0050807]; response to lipopolysaccharide [GO:0032496]; ubiquitin-dependent endocytosis [GO:0070086]	cellular protein metabolic process [GO:0044267]; cellular response to interleukin-3 [GO:0036016]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-3-mediated signaling pathway [GO:0038156]; interleukin-5-mediated signaling pathway [GO:0038043]; MAPK cascade [GO:0000165]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]	cytokine-mediated signaling pathway [GO:0019221]; negative regulation of autophagy [GO:0010507]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of synapse organization [GO:0050807]; response to lipopolysaccharide [GO:0032496]; ubiquitin-dependent endocytosis [GO:0070086]	granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytokine receptor activity [GO:0004896]; signaling receptor activity [GO:0038023]	cytokine receptor activity [GO:0004896]; interleukin-10 binding [GO:0019969]; interleukin-10 receptor activity [GO:0004920]; signaling receptor activity [GO:0038023]
d1ghb.1_d3a8ca___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1ghfh1_d1b0wc___1		Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d1ghfh1_d1h3ub2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ghfh2_d3tnmb2__1												
d1ghja__d3tzuc___1			Proteobacteria	Actinobacteria	oxoglutarate dehydrogenase complex [GO:0045252]; dihydrolipoyllysine-residue succinyltransferase activity [GO:0004149]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; tricarboxylic acid cycle [GO:0006099]	glycine cleavage complex [GO:0005960]; glycine decarboxylation via glycine cleavage system [GO:0019464]	L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; tricarboxylic acid cycle [GO:0006099]	glycine decarboxylation via glycine cleavage system [GO:0019464]	oxoglutarate dehydrogenase complex [GO:0045252]	glycine cleavage complex [GO:0005960]	dihydrolipoyllysine-residue succinyltransferase activity [GO:0004149]	
d1ghla__d170la___1	Metazoa		Chordata		extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ghlb__d5lafa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ghoi1_d2vjxb1__1				Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]
d1ghoi2_d2vzoa5__1				Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1ghoj2_d2vo5b3__1				Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]
d1ghoj3_d3ziwf2__1				Firmicutes		extracellular region [GO:0005576]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		toxin activity [GO:0090729]
d1ghok1_d3i3bb4__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1ghok5_d4pbga___1				Firmicutes		6-phospho-beta-galactosidase activity [GO:0033920]; lactose catabolic process via tagatose-6-phosphate [GO:0019512]		lactose catabolic process via tagatose-6-phosphate [GO:0019512]				6-phospho-beta-galactosidase activity [GO:0033920]
d1ghol2_d3t0bc2__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1ghom1_d2vl4b1__1				Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]
d1ghom2_d3dymc2__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1ghon2_d5c71b2__1		Fungi		Ascomycota		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1ghoo5_d1h11a___1				Firmicutes		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]
d1ghoo5_d3f5jb___1		Viridiplantae		Streptophyta		extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d1ghop2_d1f49f1__1												
d1ghra__d1j0ka3__1	Viridiplantae		Streptophyta	Firmicutes	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			licheninase activity [GO:0042972]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1ghra__d1jyye5__1	Viridiplantae		Streptophyta		licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				licheninase activity [GO:0042972]	
d1ghsa__d1jdda2__1	Viridiplantae		Streptophyta	Proteobacteria	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; (1->3)-beta-D-glucan catabolic process [GO:0006076]; defense response to fungus [GO:0050832]	extracellular region [GO:0005576]; glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; starch catabolic process [GO:0005983]	(1->3)-beta-D-glucan catabolic process [GO:0006076]; defense response to fungus [GO:0050832]	starch catabolic process [GO:0005983]		extracellular region [GO:0005576]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]	glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1ghsb__d3vgba2__1	Viridiplantae		Streptophyta	Crenarchaeota	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; (1->3)-beta-D-glucan catabolic process [GO:0006076]; defense response to fungus [GO:0050832]	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	(1->3)-beta-D-glucan catabolic process [GO:0006076]; defense response to fungus [GO:0050832]	trehalose biosynthetic process [GO:0005992]		cytoplasm [GO:0005737]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]
d1ghta__d1zr4d2__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]	DNA integration [GO:0015074]	DNA integration [GO:0015074]			DNA binding [GO:0003677]; recombinase activity [GO:0000150]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]
d1ghua__d1oo4a___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; insulin-like growth factor receptor binding [GO:0005159]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; growth hormone receptor signaling pathway [GO:0060396]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; growth hormone receptor signaling pathway [GO:0060396]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]
d1ghv.1_d1kxba___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]
d1ghw.1_d1ggd.1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1ghy.1_d3szna___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1gi3a__d5gj4f___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1gi4a__d2cgab___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1gi7.1_d4b2bc___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	digestion [GO:0007586]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1gi8.1_d3aw1a___1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1gifa__d1dptb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; cytokine receptor binding [GO:0005126]; D-dopachrome decarboxylase activity [GO:0033981]; dopachrome isomerase activity [GO:0004167]; phenylpyruvate tautomerase activity [GO:0050178]; melanin biosynthetic process [GO:0042438]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of tumor necrosis factor production [GO:0032760]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	melanin biosynthetic process [GO:0042438]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of tumor necrosis factor production [GO:0032760]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	cytokine receptor binding [GO:0005126]; D-dopachrome decarboxylase activity [GO:0033981]; dopachrome isomerase activity [GO:0004167]; phenylpyruvate tautomerase activity [GO:0050178]
d1gifb__d2aagc___1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	
d1gigh1_d1bgxh1__1	Metazoa		Chordata	Deinococcus-Thermus		DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]		DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]				DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]
d1gigh1_d5bmfl1__1	Metazoa		Chordata									
d1gigl1_d1o0vb3__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1gigl2_d4zncf2__1	Metazoa	Metazoa	Chordata	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1giqb2_d5kppb2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; pathogenesis [GO:0009405]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1gira2_d1f0la2__1			Firmicutes		extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; pathogenesis [GO:0009405]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	nucleotide binding [GO:0000166]	identical protein binding [GO:0042802]; NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]
d1giua__d3h5ka___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1giwa__d1diqd___1	Metazoa		Chordata	Proteobacteria	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]		cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]		electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]
d1gj4.1_d2bx4a___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1gjib1_d2bemc___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; apoptotic DNA fragmentation [GO:0006309]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]		apoptotic DNA fragmentation [GO:0006309]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]		chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	
d1gjma__d4ipwa___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]
d1gjqb1_d2b10b1__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	periplasmic space [GO:0042597]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1gjua2_d2wc3c___1			Thermotogae	Thermotogae	transferase activity [GO:0016740]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]			transferase activity [GO:0016740]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1gjxa__d2edga1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]; aminomethyltransferase activity [GO:0004047]; enzyme binding [GO:0019899]; glycine decarboxylation via glycine cleavage system [GO:0019464]; protein lipoylation [GO:0009249]	cell redox homeostasis [GO:0045454]	glycine decarboxylation via glycine cleavage system [GO:0019464]; protein lipoylation [GO:0009249]	cell [GO:0005623]	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]	dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	aminomethyltransferase activity [GO:0004047]; enzyme binding [GO:0019899]
d1gjya__d1boca___1	Metazoa	Metazoa	Chordata	Chordata	membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]; calcium ion binding [GO:0005509]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]			membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]
d1gk2a__d1yfea___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; histidine ammonia-lyase activity [GO:0004397]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]	tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]	fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	tricarboxylic acid cycle enzyme complex [GO:0045239]	histidine ammonia-lyase activity [GO:0004397]	fumarate hydratase activity [GO:0004333]
d1gk8i__d1ir22___1	Viridiplantae	Viridiplantae	Chlorophyta	Chlorophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1gk8k__d1rblo___1	Viridiplantae		Chlorophyta	Cyanobacteria	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]		magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1gk8o__d1ir25___1	Viridiplantae	Viridiplantae	Chlorophyta	Chlorophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1gkaa__d3vg4a1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular space [GO:0005615]; pigment binding [GO:0031409]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]		cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	extracellular space [GO:0005615]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	pigment binding [GO:0031409]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]
d1gkab__d1qwda1__1	Metazoa		Arthropoda	Proteobacteria	extracellular space [GO:0005615]; pigment binding [GO:0031409]	cell outer membrane [GO:0009279]; cytoplasm [GO:0005737]; lipid binding [GO:0008289]; cellular response to DNA damage stimulus [GO:0006974]; lipid metabolic process [GO:0006629]; response to reactive oxygen species [GO:0000302]		cellular response to DNA damage stimulus [GO:0006974]; lipid metabolic process [GO:0006629]; response to reactive oxygen species [GO:0000302]	extracellular space [GO:0005615]	cell outer membrane [GO:0009279]; cytoplasm [GO:0005737]	pigment binding [GO:0031409]	lipid binding [GO:0008289]
d1gkcb__d1iaea___1	Metazoa	Metazoa	Chordata	Arthropoda	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	cortical granule [GO:0060473]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; aspartic-type peptidase activity [GO:0070001]; glutamic-type peptidase activity [GO:0070002]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]; cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	cortical granule [GO:0060473]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	aspartic-type peptidase activity [GO:0070001]; glutamic-type peptidase activity [GO:0070002]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]
d1gkdb__d5m69e___1	Metazoa		Chordata	Firmicutes	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]		collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1gkec__d3do4h___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1gkec__d3iwuh___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1gkla1_d2hm7a___1			Firmicutes	Firmicutes	cellulosome [GO:0043263]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	hydrolase activity [GO:0016787]	xylan catabolic process [GO:0045493]		cellulosome [GO:0043263]		endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity [GO:0016787]
d1gksa__d1qn2a___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1gkxa1_d2pnra1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrion [GO:0005739]; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity [GO:0047323]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; glucose metabolic process [GO:0006006]; hypoxia-inducible factor-1alpha signaling pathway [GO:0097411]; peptidyl-serine phosphorylation [GO:0018105]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of glucose metabolic process [GO:0010906]; regulation of reactive oxygen species metabolic process [GO:2000377]	branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; glucose metabolic process [GO:0006006]; hypoxia-inducible factor-1alpha signaling pathway [GO:0097411]; peptidyl-serine phosphorylation [GO:0018105]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of glucose metabolic process [GO:0010906]; regulation of reactive oxygen species metabolic process [GO:2000377]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrion [GO:0005739]	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity [GO:0047323]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740]
d1gl4b__d2dypd1__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; calcium ion binding [GO:0005509]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell death [GO:0060548]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; tissue development [GO:0009888]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell death [GO:0060548]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; tissue development [GO:0009888]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	calcium ion binding [GO:0005509]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1gl8a__d4rqra1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cell [GO:0005623]; chloroplast [GO:0009507]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; glutathione oxidoreductase activity [GO:0097573]; protein N-terminus binding [GO:0047485]; cell redox homeostasis [GO:0045454]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of membrane potential [GO:0045838]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein deglutathionylation [GO:0080058]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of membrane potential [GO:0045838]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein deglutathionylation [GO:0080058]	cell [GO:0005623]; chloroplast [GO:0009507]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	protein disulfide oxidoreductase activity [GO:0015035]	electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; glutathione oxidoreductase activity [GO:0097573]; protein N-terminus binding [GO:0047485]
d1gl9b2_d2ia5d2__1			Euryarchaeota		ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; zinc ion binding [GO:0008270]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; deoxynucleotide 3'-phosphatase activity [GO:0047846]; DNA repair [GO:0006281]; viral process [GO:0016032]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	DNA repair [GO:0006281]; viral process [GO:0016032]			ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; deoxynucleotide 3'-phosphatase activity [GO:0047846]
d1glag2_d5aqpa1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; membrane [GO:0016020]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; negative regulation of carbohydrate metabolic process [GO:0045912]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	negative regulation of carbohydrate metabolic process [GO:0045912]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	kinase activity [GO:0016301]; metal ion binding [GO:0046872]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d1glbg2_d3o6wb2__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cytosol [GO:0005829]	cell [GO:0005623]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]
d1glcg2_d3h3oo2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; membrane [GO:0016020]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; negative regulation of carbohydrate metabolic process [GO:0045912]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	negative regulation of carbohydrate metabolic process [GO:0045912]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; membrane [GO:0016020]		kinase activity [GO:0016301]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d1gldg2_d3o80a2__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; membrane [GO:0016020]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; negative regulation of carbohydrate metabolic process [GO:0045912]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	negative regulation of carbohydrate metabolic process [GO:0045912]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; membrane [GO:0016020]	cell [GO:0005623]	kinase activity [GO:0016301]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]
d1glfo2_d1czan3__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1glfx1_d2p3rd3__1			Proteobacteria		cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]		cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]		cytosol [GO:0005829]		ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	
d1glfy1_d3h45x1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	cytosol [GO:0005829]		ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d1glfz1_d1bu6y1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d1glib__d5fvbh___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1gljo1_d1botz1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d1gljo1_d3m6ga2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytosol [GO:0005829]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d1gljo2_d1ba0a2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d1gljy1_d3o80a1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cytosol [GO:0005829]	cell [GO:0005623]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]
d1gllo1_d1glbg2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d1glna2_d2qtrb___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	glutamyl-tRNA aminoacylation [GO:0006424]	NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]
d1gloa__d1ex0b4__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1gloa__d2bdla___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d1glpa2_d1b48a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1glpb1_d4ivfh2__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	
d1glqb2_d1gsbb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d1glqb2_d4wetb___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	cell [GO:0005623]; periplasmic space [GO:0042597]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]
d1gm1a__d4e35b___1	Metazoa	Metazoa	Chordata	Chordata	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; midbody [GO:0030496]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; midbody [GO:0030496]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]	ion channel binding [GO:0044325]
d1gm3h2_d1q9ta3__1												
d1gm4a__d3selx___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfur utilization [GO:0006791]		sulfur utilization [GO:0006791]			electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1gmc.1_d1g34a___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]		digestion [GO:0007586]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	
d1gmd.1_d1o2g.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d1gmeb__d4ylcd1__1	Viridiplantae		Streptophyta	Crenarchaeota	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]		protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1gmec__d5ds2b___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	identical protein binding [GO:0042802]
d1gmed__d3gufb___1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]		protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	
d1gmpa__d1loya___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1gmqa__d1ucib___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1gmqb__d9rnta___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1gmrb__d1brnl___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1gmsa__d1gph12__1				Firmicutes		4 iron, 4 sulfur cluster binding [GO:0051539]; amidophosphoribosyltransferase activity [GO:0004044]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]		'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]				4 iron, 4 sulfur cluster binding [GO:0051539]; amidophosphoribosyltransferase activity [GO:0004044]; magnesium ion binding [GO:0000287]
d1gmya__d2nqdb___1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]	cell surface [GO:0009986]; ciliary pocket [GO:0020016]; cytoplasmic vesicle [GO:0031410]; cysteine-type endopeptidase inhibitor activity [GO:0004869]	cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]	cell surface [GO:0009986]; ciliary pocket [GO:0020016]; cytoplasmic vesicle [GO:0031410]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]	cysteine-type endopeptidase inhibitor activity [GO:0004869]
d1gmya__d4klbb___1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]	cysteine-type endopeptidase activity [GO:0004197]	cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]	cysteine-type endopeptidase activity [GO:0004197]
d1gn2a1_d2cw2a1__1			Actinobacteria	Perkinsozoa	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn2a2_d1gn4c2__1			Actinobacteria	Actinobacteria	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn2b2_d2nybc2__1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]
d1gn2c1_d2cw2b1__1			Actinobacteria	Perkinsozoa	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn2c2_d4l2bb2__1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn2d1_d4yiob1__1			Actinobacteria	Firmicutes	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn2e2_d1ja8b2__1		Metazoa	Actinobacteria	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn2f2_d3kkyb2__1			Actinobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn4c1_d4f2na1__1			Actinobacteria		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	mitochondrion [GO:0005739]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn4d1_d4l2da1__1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn4d2_d1pm9a2__1		Metazoa	Actinobacteria	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn4d2_d5a9ga2__1			Actinobacteria	Bacteroidetes	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn6a1_d3ljfb1__1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn6a2_d1gn2d2__1			Actinobacteria	Actinobacteria	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn6b1_d1uerb1__1			Actinobacteria	Bacteroidetes	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn6c1_d4l2ba1__1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn6d2_d1pl4c2__1		Metazoa	Actinobacteria	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gn8a__d3e27b___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	coenzyme A biosynthetic process [GO:0015937]	NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]
d1gn8b__d4zcsa___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	choline-phosphate cytidylyltransferase activity [GO:0004105]; identical protein binding [GO:0042802]; phosphatidylcholine binding [GO:0031210]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	choline-phosphate cytidylyltransferase activity [GO:0004105]; identical protein binding [GO:0042802]; phosphatidylcholine binding [GO:0031210]
d1gnea1_d4qq7a2__1	Metazoa		Platyhelminthes	Proteobacteria	glutathione transferase activity [GO:0004364]						glutathione transferase activity [GO:0004364]	
d1gnea2_d1pd212__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; glutathione metabolic process [GO:0006749]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693]		glutathione metabolic process [GO:0006749]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693]		cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1gnhd__d4avse___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1gnhf__d2rg0c___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1gnhg__d1ritb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1gnhi__d2a3xb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1gnhj__d4yg6a1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	
d1gnia1_d4or0a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1gnna__d2avqa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1gnnb__d5p3ua___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1gnoa__d1leea___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1gnob__d5p5sa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1gnua__d5af4a___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; synapse [GO:0045202]; beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; chemical synaptic transmission [GO:0007268]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein targeting [GO:0006605]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; chemical synaptic transmission [GO:0007268]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein targeting [GO:0006605]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; synapse [GO:0045202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1gnwa1_d1gsea1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1gnwb1_d5jcwb2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1go1a__d1e7kb___1		Metazoa	Euryarchaeota	Chordata	cytosolic large ribosomal subunit [GO:0022625]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	box C/D snoRNP complex [GO:0031428]; dense fibrillar component [GO:0001651]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; small-subunit processome [GO:0032040]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4atac snRNP [GO:0005690]; ATPase binding [GO:0051117]; box C/D snoRNA binding [GO:0034512]; RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511]; U4 snRNA binding [GO:0030621]; U4atac snRNA binding [GO:0030622]; box C/D snoRNP assembly [GO:0000492]; maturation of LSU-rRNA [GO:0000470]; mRNA splicing, via spliceosome [GO:0000398]; rRNA processing [GO:0006364]; single fertilization [GO:0007338]	translation [GO:0006412]	box C/D snoRNP assembly [GO:0000492]; maturation of LSU-rRNA [GO:0000470]; mRNA splicing, via spliceosome [GO:0000398]; rRNA processing [GO:0006364]; single fertilization [GO:0007338]	cytosolic large ribosomal subunit [GO:0022625]	box C/D snoRNP complex [GO:0031428]; dense fibrillar component [GO:0001651]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; small-subunit processome [GO:0032040]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4atac snRNP [GO:0005690]	RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]	ATPase binding [GO:0051117]; box C/D snoRNA binding [GO:0034512]; RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511]; U4atac snRNA binding [GO:0030622]; U4 snRNA binding [GO:0030621]
d1go2a2_d4yaua3__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	phycobilisome [GO:0030089]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1go7p2_d4mkta2__1		Metazoa	Proteobacteria	Chordata	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1goaa__d2ze2a2__1			Proteobacteria		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1goba__d3lana2__1			Proteobacteria		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1goca__d1jlaa1__1			Proteobacteria		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1gofa2_d1czsa___1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]		blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]	extracellular region [GO:0005576]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]
d1goga3_d2eica3__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]
d1goha2_d3e1f41__1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1goka__d1r87a___1	Fungi		Ascomycota	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d1goka__d3t0db3__1	Fungi		Ascomycota	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	endo-1,4-beta-xylanase activity [GO:0031176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1goma__d1h4pa___1	Fungi	Fungi	Ascomycota	Ascomycota	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; fungal-type vacuole [GO:0000324]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]	xylan catabolic process [GO:0045493]	cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]		extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; fungal-type vacuole [GO:0000324]	endo-1,4-beta-xylanase activity [GO:0031176]	glucan exo-1,3-beta-glucosidase activity [GO:0004338]
d1goma__d4lyqa1__1	Fungi		Ascomycota		endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	
d1gora__d3edeb2__1	Fungi		Ascomycota	Bacteroidetes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d1gosa2_d1cc4a2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1gosb2_d1el8a2__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	tetrahydrofolate metabolic process [GO:0046653]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	sarcosine oxidase activity [GO:0008115]
d1gowb__d1e56b___1		Viridiplantae	Crenarchaeota	Streptophyta	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]		chloroplast [GO:0009507]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]	beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]
d1gowb__d1piga2__1		Metazoa	Crenarchaeota	Chordata	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]		extracellular space [GO:0005615]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1goya__d1i70b___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1goya__d5hohb___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1goyb__d1iyya___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1gozb2_d1ts3a2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1gp2b__d4bh6a___1	Metazoa	Fungi	Chordata	Ascomycota	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin-protein transferase inhibitor activity [GO:0055105]; cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of ubiquitin protein ligase activity [GO:1904667]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of ubiquitin protein ligase activity [GO:1904667]	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]	ubiquitin-protein transferase inhibitor activity [GO:0055105]
d1gp6a__d5pira___1	Viridiplantae	Metazoa	Streptophyta	Chordata	dioxygenase activity [GO:0051213]; L-ascorbic acid binding [GO:0031418]; leucocyanidin oxygenase activity [GO:0050589]; metal ion binding [GO:0046872]; anthocyanin-containing compound biosynthetic process [GO:0009718]; proanthocyanidin biosynthetic process [GO:0010023]; response to jasmonic acid [GO:0009753]; response to wounding [GO:0009611]; vacuole organization [GO:0007033]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	anthocyanin-containing compound biosynthetic process [GO:0009718]; proanthocyanidin biosynthetic process [GO:0010023]; response to jasmonic acid [GO:0009753]; response to wounding [GO:0009611]; vacuole organization [GO:0007033]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]		blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	dioxygenase activity [GO:0051213]; L-ascorbic acid binding [GO:0031418]; leucocyanidin oxygenase activity [GO:0050589]; metal ion binding [GO:0046872]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d1gpca__d2gn5a___1					metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; rolling circle single-stranded viral DNA replication [GO:0039684]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; rolling circle single-stranded viral DNA replication [GO:0039684]			metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]	single-stranded DNA binding [GO:0003697]
d1gpdg2_d2g82p2__1	Metazoa		Arthropoda	Deinococcus-Thermus	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1gpea2_d1h84b2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; flavin adenine dinucleotide binding [GO:0050660]; glucose oxidase activity [GO:0046562]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]		polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	extracellular region [GO:0005576]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	flavin adenine dinucleotide binding [GO:0050660]; glucose oxidase activity [GO:0046562]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]
d1gph31_d4mb6a___1			Firmicutes	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; amidophosphoribosyltransferase activity [GO:0004044]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; adenine phosphoribosyltransferase activity [GO:0003999]; adenine salvage [GO:0006168]; AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	adenine salvage [GO:0006168]; AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]		cytoplasm [GO:0005737]	4 iron, 4 sulfur cluster binding [GO:0051539]; amidophosphoribosyltransferase activity [GO:0004044]; magnesium ion binding [GO:0000287]	adenine phosphoribosyltransferase activity [GO:0003999]
d1gph32_d1q19b2__1			Firmicutes	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; amidophosphoribosyltransferase activity [GO:0004044]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]; antibiotic biosynthetic process [GO:0017000]; asparagine biosynthetic process [GO:0006529]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	antibiotic biosynthetic process [GO:0017000]; asparagine biosynthetic process [GO:0006529]			4 iron, 4 sulfur cluster binding [GO:0051539]; amidophosphoribosyltransferase activity [GO:0004044]; magnesium ion binding [GO:0000287]	asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]
d1gph41_d5e38c1__1			Firmicutes	Actinobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; amidophosphoribosyltransferase activity [GO:0004044]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]		cytosol [GO:0005829]; plasma membrane [GO:0005886]	4 iron, 4 sulfur cluster binding [GO:0051539]; amidophosphoribosyltransferase activity [GO:0004044]; magnesium ion binding [GO:0000287]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]
d1gpia__d3ojbb1__1	Fungi	Metazoa	Basidiomycota	Chordata	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	cellulose catabolic process [GO:0030245]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d1gpja2_d3etga2__1		Metazoa	Euryarchaeota	Chordata	glutamyl-tRNA reductase activity [GO:0008883]; NADP binding [GO:0050661]; protoporphyrinogen IX biosynthetic process [GO:0006782]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	protoporphyrinogen IX biosynthetic process [GO:0006782]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamyl-tRNA reductase activity [GO:0008883]; NADP binding [GO:0050661]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1gpla2_d3kooa2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; intestinal cholesterol absorption [GO:0030299]; lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241]; lipid metabolic process [GO:0006629]; positive regulation of triglyceride lipase activity [GO:0061365]; retinoid metabolic process [GO:0001523]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	intestinal cholesterol absorption [GO:0030299]; lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241]; lipid metabolic process [GO:0006629]; positive regulation of triglyceride lipase activity [GO:0061365]; retinoid metabolic process [GO:0001523]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d1gpoi2_d3mr9b1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1gpoi2_d4hiic2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1gpol1_d2itdb2__1	Metazoa		Chordata	Actinobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	voltage-gated potassium channel complex [GO:0008076]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1gpol2_d5l7xl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1gpom1_d3to4a2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1gpqc__d1cuqa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gpra__d2mp0b___1			Firmicutes	Proteobacteria	D-glucosamine PTS permease activity [GO:0103111]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; membrane [GO:0016020]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; negative regulation of carbohydrate metabolic process [GO:0045912]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	negative regulation of carbohydrate metabolic process [GO:0045912]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]		cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; membrane [GO:0016020]	D-glucosamine PTS permease activity [GO:0103111]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]	kinase activity [GO:0016301]; metal ion binding [GO:0046872]
d1gpua3_d3exhh2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	pentose-phosphate shunt [GO:0006098]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1gpub1_d1r9ja2__1	Fungi		Ascomycota		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1gpwa__d3zs4a___1			Thermotogae	Actinobacteria	cytoplasm [GO:0005737]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; histidine biosynthetic process [GO:0000105]	cytoplasm [GO:0005737]; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]; phosphoribosylanthranilate isomerase activity [GO:0004640]; histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]	histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]; phosphoribosylanthranilate isomerase activity [GO:0004640]
d1gpwd__d1t36h2__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; histidine biosynthetic process [GO:0000105]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	histidine biosynthetic process [GO:0000105]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1gpxa__d3eubs1__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1gq1a1_d4qaoa1__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	periplasmic space [GO:0042597]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1gq1a2_d1bl9a2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1gq7c__d2v5wa___1		Metazoa	Actinobacteria	Chordata	metal ion binding [GO:0046872]; proclavaminate amidinohydrolase activity [GO:0033972]; clavulanic acid biosynthetic process [GO:0033050]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	clavulanic acid biosynthetic process [GO:0033050]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]		cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; proclavaminate amidinohydrolase activity [GO:0033972]	histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]
d1gq7c__d4cevd___1			Actinobacteria	Firmicutes	metal ion binding [GO:0046872]; proclavaminate amidinohydrolase activity [GO:0033972]; clavulanic acid biosynthetic process [GO:0033050]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	clavulanic acid biosynthetic process [GO:0033050]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]			metal ion binding [GO:0046872]; proclavaminate amidinohydrolase activity [GO:0033972]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]
d1gq7f__d2zava___1		Metazoa	Actinobacteria	Chordata	metal ion binding [GO:0046872]; proclavaminate amidinohydrolase activity [GO:0033972]; clavulanic acid biosynthetic process [GO:0033050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	clavulanic acid biosynthetic process [GO:0033050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	metal ion binding [GO:0046872]; proclavaminate amidinohydrolase activity [GO:0033972]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1gq8a__d1xg2a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cell wall [GO:0005618]; extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	cytoplasm [GO:0005737]; pectinesterase inhibitor activity [GO:0046910]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]		cell wall [GO:0005618]; extracellular region [GO:0005576]	cytoplasm [GO:0005737]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]	pectinesterase inhibitor activity [GO:0046910]
d1gq9b__d5ifyc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; extracellular polysaccharide biosynthetic process [GO:0045226]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	extracellular polysaccharide biosynthetic process [GO:0045226]	cytoplasm [GO:0005737]		3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]
d1gqca__d1jyla1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	metal ion binding [GO:0046872]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]		cytoplasm [GO:0005737]		3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]	metal ion binding [GO:0046872]
d1gqca__d2vkda1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; pathogenesis [GO:0009405]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	pathogenesis [GO:0009405]	cytoplasm [GO:0005737]		3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]
d1gqcb__d2jcoa___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	cytoplasm [GO:0005737]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d1gqia1_d2v5ca2__1			Proteobacteria	Firmicutes	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	glucuronoxylan catabolic process [GO:2000886]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]		alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d1gqib1_d2xfya___1		Viridiplantae	Proteobacteria	Streptophyta	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; identical protein binding [GO:0042802]; polysaccharide catabolic process [GO:0000272]	glucuronoxylan catabolic process [GO:2000886]	polysaccharide catabolic process [GO:0000272]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]		alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; identical protein binding [GO:0042802]
d1gqja1_d2j4ga2__1			Proteobacteria	Bacteroidetes	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	glucuronoxylan catabolic process [GO:2000886]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]		alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]
d1gqja1_d4txea___1		Fungi	Proteobacteria	Ascomycota	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	cellular bud neck [GO:0005935]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; fungal-type vacuole [GO:0000324]; nuclear envelope [GO:0005635]; chitin binding [GO:0008061]; endochitinase activity [GO:0008843]; cell wall organization [GO:0071555]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]; septum digestion after cytokinesis [GO:0000920]	glucuronoxylan catabolic process [GO:2000886]	cell wall organization [GO:0071555]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]; septum digestion after cytokinesis [GO:0000920]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]	cellular bud neck [GO:0005935]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; fungal-type vacuole [GO:0000324]; nuclear envelope [GO:0005635]	alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]	chitin binding [GO:0008061]; endochitinase activity [GO:0008843]
d1gqja2_d4c7db1__1			Proteobacteria	Actinobacteria	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	glucuronoxylan catabolic process [GO:2000886]	carbohydrate metabolic process [GO:0005975]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]		alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]	beta-N-acetylhexosaminidase activity [GO:0004563]
d1gqla1_d2w67b2__1			Proteobacteria	Bacteroidetes	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	glucuronoxylan catabolic process [GO:2000886]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]		alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]
d1gqla1_d3mmwa___1			Proteobacteria	Thermotogae	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	glucuronoxylan catabolic process [GO:2000886]	cellular glucan metabolic process [GO:0006073]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1gqla2_d1k9fa2__1			Proteobacteria	Firmicutes	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	glucuronoxylan catabolic process [GO:2000886]	glucuronoxylan catabolic process [GO:2000886]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]	alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]
d1gqlb2_d2x0ya1__1			Proteobacteria	Firmicutes	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	glucuronoxylan catabolic process [GO:2000886]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]		alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d1gqma__d1ksoa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]
d1gqme__d1b4ca___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1gqme__d5m6ce___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendrite membrane [GO:0032590]; dendritic spine head [GO:0044327]; extrinsic component of membrane [GO:0019898]; glutamatergic synapse [GO:0098978]; neuronal cell body membrane [GO:0032809]; perikaryon [GO:0043204]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; activation of phospholipase D activity [GO:0031584]; brain development [GO:0007420]; calcium-mediated signaling [GO:0019722]; cellular response to calcium ion [GO:0071277]; cellular response to electrical stimulus [GO:0071257]; cellular response to monosodium glutamate [GO:1904009]; inner ear development [GO:0048839]; negative regulation of guanylate cyclase activity [GO:0031283]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to Aroclor 1254 [GO:1904010]; response to ketamine [GO:1901986]; response to L-glutamate [GO:1902065]; retina development in camera-type eye [GO:0060041]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	activation of phospholipase D activity [GO:0031584]; brain development [GO:0007420]; calcium-mediated signaling [GO:0019722]; cellular response to calcium ion [GO:0071277]; cellular response to electrical stimulus [GO:0071257]; cellular response to monosodium glutamate [GO:1904009]; inner ear development [GO:0048839]; negative regulation of guanylate cyclase activity [GO:0031283]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to Aroclor 1254 [GO:1904010]; response to ketamine [GO:1901986]; response to L-glutamate [GO:1902065]; retina development in camera-type eye [GO:0060041]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendrite membrane [GO:0032590]; dendritic spine head [GO:0044327]; extrinsic component of membrane [GO:0019898]; glutamatergic synapse [GO:0098978]; neuronal cell body membrane [GO:0032809]; perikaryon [GO:0043204]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]
d1gqmg__d1m39a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; intracellular [GO:0005622]; nuclear pore nuclear basket [GO:0044615]; nucleoplasm [GO:0005654]; photoreceptor connecting cilium [GO:0032391]; transcription export complex 2 [GO:0070390]; XPC complex [GO:0071942]; calcium ion binding [GO:0005509]; G-protein beta/gamma-subunit complex binding [GO:0031683]; heterotrimeric G-protein binding [GO:0032795]; microtubule binding [GO:0008017]; cell division [GO:0051301]; centriole replication [GO:0007099]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; global genome nucleotide-excision repair [GO:0070911]; mitotic cell cycle [GO:0000278]; mRNA transport [GO:0051028]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; protein transport [GO:0015031]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; spermatogenesis [GO:0007283]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	cell division [GO:0051301]; centriole replication [GO:0007099]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; global genome nucleotide-excision repair [GO:0070911]; mitotic cell cycle [GO:0000278]; mRNA transport [GO:0051028]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; protein transport [GO:0015031]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; intracellular [GO:0005622]; nuclear pore nuclear basket [GO:0044615]; nucleoplasm [GO:0005654]; photoreceptor connecting cilium [GO:0032391]; transcription export complex 2 [GO:0070390]; XPC complex [GO:0071942]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; G-protein beta/gamma-subunit complex binding [GO:0031683]; heterotrimeric G-protein binding [GO:0032795]; microtubule binding [GO:0008017]
d1gqoc__d2bt4f___1			Firmicutes	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gqoi__d5yl5i___1			Firmicutes	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gqoj__d1gu1k___1			Firmicutes	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gqoj__d5x47l___1			Firmicutes	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gqqa1_d2jffa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]
d1gqqb1_d2uuoa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]
d1gqsa__d4k6gb1__1	Metazoa	Fungi	Chordata	Basidiomycota	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	lipid catabolic process [GO:0016042]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]		acetylcholinesterase activity [GO:0003990]	triglyceride lipase activity [GO:0004806]
d1gqtc__d1wyee___1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	D-ribose catabolic process [GO:0019303]		cytosol [GO:0005829]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]
d1gqya1_d2uupa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]
d1gqza1_d5iwea2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	lysine biosynthetic process via diaminopimelate [GO:0009089]	pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	cytosol [GO:0005829]		diaminopimelate epimerase activity [GO:0008837]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]
d1gr1a1_d1ep1b1__1			Cyanobacteria	Firmicutes	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; 'de novo' UMP biosynthetic process [GO:0044205]	oxidation-reduction process [GO:0055114]	'de novo' UMP biosynthetic process [GO:0044205]	phycobilisome [GO:0030089]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]
d1gr1a1_d5tr9b1__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	ferredoxin-NADP+ reductase activity [GO:0004324]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]		ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1gr1a2_d1w35a2__1			Cyanobacteria	Cyanobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	phycobilisome [GO:0030089]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d1gr3a__d5mu8y___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; metal ion binding [GO:0046872]; extracellular matrix organization [GO:0030198]; skeletal system development [GO:0001501]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	extracellular matrix organization [GO:0030198]; skeletal system development [GO:0001501]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; metal ion binding [GO:0046872]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d1gr8b__d1obla___1				Proteobacteria		amidase activity [GO:0004040]						amidase activity [GO:0004040]
d1graa2_d1fcda2__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	periplasmic space [GO:0042597]; flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]		cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]
d1grla2_d5cdja___1		Viridiplantae	Proteobacteria	Chlorophyta	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	chloroplast [GO:0009507]; ATP binding [GO:0005524]; protein refolding [GO:0042026]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	protein refolding [GO:0042026]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	chloroplast [GO:0009507]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]
d1grlb2_d1q3qa2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1grlb2_d1xckk3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]
d1grlc2_d3vz8c___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]
d1grld2_d1q3ra2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1grle2_d1xckl3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]
d1grlg2_d5cdka1__1		Viridiplantae	Proteobacteria	Chlorophyta	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; protein refolding [GO:0042026]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	protein refolding [GO:0042026]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]
d1grpa__d5h3eb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; isocitrate dehydrogenase activity [GO:0004448]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; 2-oxoglutarate metabolic process [GO:0006103]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP biosynthetic process [GO:0006741]; NADP metabolic process [GO:0006739]; negative regulation of glial cell migration [GO:1903976]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of matrix metallopeptidase secretion [GO:1904465]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	2-oxoglutarate metabolic process [GO:0006103]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP biosynthetic process [GO:0006741]; NADP metabolic process [GO:0006739]; negative regulation of glial cell migration [GO:1903976]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of matrix metallopeptidase secretion [GO:1904465]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; isocitrate dehydrogenase activity [GO:0004448]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1gs0a2_d4zzxb2__1	Metazoa	Metazoa	Chordata	Chordata	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; base-excision repair [GO:0006284]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of neuron death [GO:1901215]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; protein poly-ADP-ribosylation [GO:0070212]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; base-excision repair [GO:0006284]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of neuron death [GO:1901215]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; protein ADP-ribosylation [GO:0006471]; protein poly-ADP-ribosylation [GO:0070212]	base-excision repair [GO:0006284]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of neuron death [GO:1901215]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; protein poly-ADP-ribosylation [GO:0070212]	base-excision repair [GO:0006284]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of neuron death [GO:1901215]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; protein ADP-ribosylation [GO:0006471]; protein poly-ADP-ribosylation [GO:0070212]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]	DNA binding [GO:0003677]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]
d1gs0b2_d1mdta2__1	Metazoa		Chordata		nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; base-excision repair [GO:0006284]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of neuron death [GO:1901215]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; protein poly-ADP-ribosylation [GO:0070212]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]	base-excision repair [GO:0006284]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of neuron death [GO:1901215]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; protein poly-ADP-ribosylation [GO:0070212]		nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]	identical protein binding [GO:0042802]; NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]
d1gs6x1_d1l9sc1__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1gs6x2_d2b08a2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1gs7a2_d3h4fc1__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1gs8a2_d4q89a2__1			Proteobacteria	Firmicutes	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	nitrogen compound metabolic process [GO:0006807]	sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1gsaa1_d1uc9a1__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; glutathione synthase activity [GO:0004363]; magnesium ion binding [GO:0000287]; glutathione biosynthetic process [GO:0006750]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	glutathione biosynthetic process [GO:0006750]	cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; glutathione synthase activity [GO:0004363]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]
d1gsba1_d5an1f2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	glutathione transferase activity [GO:0004364]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]		cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]		glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	glutathione transferase activity [GO:0004364]
d1gsba2_d1tu7b2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	glutathione transferase activity [GO:0004364]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]		cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]		glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	glutathione transferase activity [GO:0004364]
d1gsbb1_d1iyid1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1gsbc2_d3ul3b___1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; PTEX complex [GO:0097619]; symbiont-containing vacuole [GO:0020003]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; PTEX complex [GO:0097619]; symbiont-containing vacuole [GO:0020003]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1gsbd2_d2pgta2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1gsbd2_d4mh2l___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d1gsca1_d4dejb2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	transferase activity [GO:0016740]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]		cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]		glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	transferase activity [GO:0016740]
d1gscb1_d1byea1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1gscb2_d1nw2e___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cell [GO:0005623]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	protein disulfide oxidoreductase activity [GO:0015035]
d1gscc2_d1ev9d2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]; aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]
d1gscc2_d2hrna1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; copper ion binding [GO:0005507]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	copper ion binding [GO:0005507]
d1gscd2_d5a5kv1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d1gsdb1_d2vcza1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1gsdb2_d3tkpd___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d1gsdc1_d4yh2a2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d1gsdc2_d1oyjb2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d1gsdc2_d2vcva1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d1gsdd1_d2il3b2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d1gseb1_d2gdrd2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d1gsfb2_d3apsb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; chaperone binding [GO:0051087]; disulfide oxidoreductase activity [GO:0015036]; Hsp70 protein binding [GO:0030544]; misfolded protein binding [GO:0051787]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of ATPase activity [GO:0032781]; protein folding in endoplasmic reticulum [GO:0034975]; response to endoplasmic reticulum stress [GO:0034976]; ubiquitin-dependent ERAD pathway [GO:0030433]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of ATPase activity [GO:0032781]; protein folding in endoplasmic reticulum [GO:0034975]; response to endoplasmic reticulum stress [GO:0034976]; ubiquitin-dependent ERAD pathway [GO:0030433]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; chaperone binding [GO:0051087]; disulfide oxidoreductase activity [GO:0015036]; Hsp70 protein binding [GO:0030544]; misfolded protein binding [GO:0051787]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]
d1gsfc2_d1we0d___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1gsfd2_d4v2la___1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	protein disulfide oxidoreductase activity [GO:0015035]
d1gsha1_d2yzmc1__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; glutathione synthase activity [GO:0004363]; magnesium ion binding [GO:0000287]; glutathione biosynthetic process [GO:0006750]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	glutathione biosynthetic process [GO:0006750]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutathione synthase activity [GO:0004363]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1gsia__d3tmkg___1		Fungi	Actinobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; TMP metabolic process [GO:0046044]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; nucleoside diphosphate phosphorylation [GO:0006165]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; TMP metabolic process [GO:0046044]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; nucleoside diphosphate phosphorylation [GO:0006165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]
d1gsla__d2tepa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1gsma2_d1j88d2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; integrin binding involved in cell-matrix adhesion [GO:0098640]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	Fc-epsilon receptor signaling pathway [GO:0038095]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	integrin binding involved in cell-matrix adhesion [GO:0098640]	IgE binding [GO:0019863]
d1gspa__d1q9ec___1	Fungi	Fungi	Ascomycota	Ascomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1gssa1_d1u3ia2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d1gssa2_d1eema2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d1gssb1_d1gumd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1gssb1_d4nhzk2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	transferase activity [GO:0016740]
d1gssb2_d1erta___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d1gsva__d5j7ed___1		Metazoa	Proteobacteria	Chordata	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; nuclear inner membrane [GO:0005637]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; voltage-gated potassium channel complex [GO:0008076]; calmodulin binding [GO:0005516]; delayed rectifier potassium channel activity [GO:0005251]; phosphatidylinositol bisphosphate binding [GO:1902936]; voltage-gated potassium channel activity [GO:0005249]; cellular response to calcium ion [GO:0071277]; myoblast fusion [GO:0007520]; phosphatidylinositol-mediated signaling [GO:0048015]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of cell population proliferation [GO:0042127]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cellular response to calcium ion [GO:0071277]; myoblast fusion [GO:0007520]; phosphatidylinositol-mediated signaling [GO:0048015]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of cell population proliferation [GO:0042127]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]		axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; nuclear inner membrane [GO:0005637]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; voltage-gated potassium channel complex [GO:0008076]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	calmodulin binding [GO:0005516]; delayed rectifier potassium channel activity [GO:0005251]; phosphatidylinositol bisphosphate binding [GO:1902936]; voltage-gated potassium channel activity [GO:0005249]
d1gswa__d3nhqf1__1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d1gsya2_d2vcrh1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	
d1gsza2_d1tnyf___1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1gszb2_d1tnol___1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1gt1b__d3fmzb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; protein heterodimerization activity [GO:0046982]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]; cardiac muscle tissue development [GO:0048738]; embryonic organ morphogenesis [GO:0048562]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; female genitalia morphogenesis [GO:0048807]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; lung development [GO:0030324]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; urinary bladder development [GO:0060157]; uterus development [GO:0060065]; vagina development [GO:0060068]; visual perception [GO:0007601]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cardiac muscle tissue development [GO:0048738]; embryonic organ morphogenesis [GO:0048562]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; female genitalia morphogenesis [GO:0048807]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; lung development [GO:0030324]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; urinary bladder development [GO:0060157]; uterus development [GO:0060065]; vagina development [GO:0060068]; visual perception [GO:0007601]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	small molecule binding [GO:0036094]	protein heterodimerization activity [GO:0046982]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]
d1gt2a3_d1hdza2__1		Metazoa		Chordata		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1gt2a4_d4bgtd4__1												
d1gt3b__d2akqd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	small molecule binding [GO:0036094]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]
d1gt3b__d4qztc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]	small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1gt4a__d4orwb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	extracellular region [GO:0005576]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	small molecule binding [GO:0036094]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d1gt6a__d3ia2d___1	Fungi		Ascomycota	Proteobacteria	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]
d1gt6b__d1aurb___1	Fungi		Ascomycota	Proteobacteria	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	methyl indole-3-acetate esterase activity [GO:0080030]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	methyl indole-3-acetate esterase activity [GO:0080030]
d1gt7k__d1k0we___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]	aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]
d1gt7l__d2v9fa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]
d1gt8b1_d3vr9b2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d1gt8d3_d2tmdb2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]
d1gt8d3_d3dk4a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]
d1gt91__d1zvja___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1gt92__d1y4ae___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1gtba1_d2dsab2__1	Metazoa		Platyhelminthes	Proteobacteria	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]					glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1gtba2_d1jfub___1	Metazoa		Platyhelminthes	Proteobacteria	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]		cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]		cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	glutathione transferase activity [GO:0004364]	oxidoreductase activity [GO:0016491]
d1gteb1_d2wdqf2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d1gtec1_d3vr8f2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d1gted2_d3gr8b___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	FMN binding [GO:0010181]; NADP binding [GO:0050661]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]; response to toxic substance [GO:0009636]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	response to toxic substance [GO:0009636]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	FMN binding [GO:0010181]; NADP binding [GO:0050661]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]
d1gtfo__d3zteo___1			Firmicutes	Firmicutes	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d1gtha2_d4qaic___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d1gthc1_d2wdqb2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d1gthc2_d3l65a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d1gtic1_d5u51d2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	
d1gtid1_d5d9ta2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; ascorbate glutathione cycle [GO:0033355]; cellular oxidant detoxification [GO:0098869]; protein glutathionylation [GO:0010731]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	ascorbate glutathione cycle [GO:0033355]; cellular oxidant detoxification [GO:0098869]; protein glutathionylation [GO:0010731]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	cytosol [GO:0005829]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]
d1gtma1_d1zmoh___1			Euryarchaeota	Actinobacteria	cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]		cytoplasm [GO:0005737]		glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	
d1gtpa__d1n3se___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1gtpa__d1nbuf___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]
d1gtpb__d2yzdd1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1gtpd__d2yzde2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1gtpe__d3qnae___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	queuosine biosynthetic process [GO:0008616]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d1gtpf__d3qnaa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	queuosine biosynthetic process [GO:0008616]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d1gtpi__d4n9ma2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1gtpq__d1is7b___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]
d1gtpq__d3i2bh___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d1gtqa__d1a8rl___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin biosynthetic process [GO:0006729]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	tetrahydrobiopterin biosynthetic process [GO:0006729]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1gttb1_d2wqtd___1			Proteobacteria	Proteobacteria	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity [GO:0008704]; 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity [GO:0018800]; metal ion binding [GO:0046872]; 4-hydroxyphenylacetate catabolic process [GO:1901023]	cytoplasm [GO:0005737]; 2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	4-hydroxyphenylacetate catabolic process [GO:1901023]	3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]		cytoplasm [GO:0005737]	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity [GO:0008704]; 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity [GO:0018800]; metal ion binding [GO:0046872]	2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]
d1gtua2_d4gtuf2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; long-chain fatty acid biosynthetic process [GO:0042759]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; long-chain fatty acid biosynthetic process [GO:0042759]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d1gtub1_d4f0ba2__1	Metazoa	Fungi	Chordata	Basidiomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	transferase activity [GO:0016740]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	transferase activity [GO:0016740]
d1gtub2_d2c80a2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	glutathione transferase activity [GO:0004364]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d1gtub2_d2fwfa2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]; electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1gtuc2_d5an1a1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	glutathione transferase activity [GO:0004364]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d1gtva__d2jlza1__1			Actinobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; TMP metabolic process [GO:0046044]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; TMP metabolic process [GO:0046044]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1gtxd__d1sf2d___1				Proteobacteria		cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]		arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]		cytosol [GO:0005829]		4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]
d1gtzc__d4ki7o___1			Actinobacteria	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]		cytosol [GO:0005829]	3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gtze__d4rc9i___1			Actinobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gtzf__d3n87r___1			Actinobacteria	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]		cytosol [GO:0005829]	3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gtzg__d4rc9g___1			Actinobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gu0f__d5yhml___1			Actinobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gu0j__d5yhmk___1			Actinobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gu1a__d3n86e___1			Actinobacteria	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]		cytosol [GO:0005829]	3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gu1e__d3n8kf___1			Actinobacteria	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]		cytosol [GO:0005829]	3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gu1f__d4ki7u___1			Actinobacteria	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]		cytosol [GO:0005829]	3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gu1i__d4rhch___1			Actinobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gu1j__d4zc1f___1			Actinobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1gu7a2_d2jhfb2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	mitochondrion [GO:0005739]	cytosol [GO:0005829]	trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1guab__d2zvog2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; mitogen-activated protein kinase kinase binding [GO:0031434]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; activation of adenylate cyclase activity [GO:0007190]; activation of MAPKK activity [GO:0000186]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; death-inducing signaling complex assembly [GO:0071550]; face development [GO:0060324]; heart development [GO:0007507]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; intermediate filament cytoskeleton organization [GO:0045104]; ion transmembrane transport [GO:0034220]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of protein complex assembly [GO:0031333]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet activation [GO:0030168]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell differentiation [GO:0045595]; regulation of cell motility [GO:2000145]; regulation of Rho protein signal transduction [GO:0035023]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of adenylate cyclase activity [GO:0007190]; activation of MAPKK activity [GO:0000186]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; death-inducing signaling complex assembly [GO:0071550]; face development [GO:0060324]; heart development [GO:0007507]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; intermediate filament cytoskeleton organization [GO:0045104]; ion transmembrane transport [GO:0034220]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of protein complex assembly [GO:0031333]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet activation [GO:0030168]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell differentiation [GO:0045595]; regulation of cell motility [GO:2000145]; regulation of Rho protein signal transduction [GO:0035023]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; mitogen-activated protein kinase kinase binding [GO:0031434]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1gugb__d1oxta1__1			Firmicutes	Crenarchaeota	molybdate ion transport [GO:0015689]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; carbohydrate transport [GO:0008643]	molybdate ion transport [GO:0015689]	carbohydrate transport [GO:0008643]		ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]
d1guge__d1h9ja1__1			Firmicutes	Proteobacteria	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]				
d1guha1_d1xwga1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1guha1_d4ecia2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	transferase activity [GO:0016740]
d1guha2_d3apsa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; chaperone binding [GO:0051087]; disulfide oxidoreductase activity [GO:0015036]; Hsp70 protein binding [GO:0030544]; misfolded protein binding [GO:0051787]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of ATPase activity [GO:0032781]; protein folding in endoplasmic reticulum [GO:0034975]; response to endoplasmic reticulum stress [GO:0034976]; ubiquitin-dependent ERAD pathway [GO:0030433]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of ATPase activity [GO:0032781]; protein folding in endoplasmic reticulum [GO:0034975]; response to endoplasmic reticulum stress [GO:0034976]; ubiquitin-dependent ERAD pathway [GO:0030433]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; chaperone binding [GO:0051087]; disulfide oxidoreductase activity [GO:0015036]; Hsp70 protein binding [GO:0030544]; misfolded protein binding [GO:0051787]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]
d1guhb2_d5djlb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1guhc1_d4ri6b2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1guhc2_d1uuld___1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	
d1guhd1_d3isob2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d1guka1_d2n5fa2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; protein glutathionylation [GO:0010731]	cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]	protein glutathionylation [GO:0010731]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]		drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]
d1guka1_d3q74a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1gukb2_d2oaca2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]
d1gula1_d4ecjb2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]		glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	transferase activity [GO:0016740]
d1guld1_d4pnfa2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d1gule1_d5iqya2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]		glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]
d1gulf1_d4hi7b2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]		glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1gulf2_d4gtuh2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; long-chain fatty acid biosynthetic process [GO:0042759]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; long-chain fatty acid biosynthetic process [GO:0042759]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d1gulg2_d4kb3a___1	Metazoa		Chordata		cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]	cell [GO:0005623]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1gulh1_d2hqtn___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]; enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]; positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]
d1gulh2_d1jzrc2__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]
d1gumb1_d5ecrf2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytosol [GO:0005829]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1gumb2_d3mnga___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]
d1gumc1_d4ivfc2__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]		glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1gumc2_d3tkpc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d1gumd2_d3rpnf___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]
d1gumf2_d2d2zb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	actin cytoskeleton [GO:0015629]; apical part of cell [GO:0045177]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; centrosome [GO:0005813]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; microvillus [GO:0005902]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; chloride transport [GO:0006821]; endothelial cell morphogenesis [GO:0001886]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; fertilization [GO:0009566]; keratinocyte differentiation [GO:0030216]; multicellular organism growth [GO:0035264]; negative regulation of cell migration [GO:0030336]; regulation of cytoskeleton organization [GO:0051493]; regulation of ion transmembrane transport [GO:0034765]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; vacuolar acidification [GO:0007035]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; chloride transport [GO:0006821]; endothelial cell morphogenesis [GO:0001886]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; fertilization [GO:0009566]; keratinocyte differentiation [GO:0030216]; multicellular organism growth [GO:0035264]; negative regulation of cell migration [GO:0030336]; regulation of cytoskeleton organization [GO:0051493]; regulation of ion transmembrane transport [GO:0034765]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; vacuolar acidification [GO:0007035]	cytosol [GO:0005829]	actin cytoskeleton [GO:0015629]; apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; centrosome [GO:0005813]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; microvillus [GO:0005902]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]
d1gumg1_d5u56c2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]		glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1gumh2_d18gsb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1gunc__d1fr3a___1			Firmicutes	Firmicutes	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]				
d1gund__d1h9ma2__1			Firmicutes	Proteobacteria	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]				
d1guoa__d1fr3k___1			Firmicutes	Firmicutes	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]				
d1guof__d1fr3g___1			Firmicutes	Firmicutes	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]				
d1gupa2_d2q4ha2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; galactose catabolic process via UDP-galactose [GO:0033499]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	galactose catabolic process via UDP-galactose [GO:0033499]	carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]
d1gupb1_d3o1ca___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; galactose catabolic process via UDP-galactose [GO:0033499]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]	galactose catabolic process via UDP-galactose [GO:0033499]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]	ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]
d1guqa2_d1kpbb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; galactose catabolic process via UDP-galactose [GO:0033499]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	galactose catabolic process via UDP-galactose [GO:0033499]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d1guqb2_d5ipca___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; galactose catabolic process via UDP-galactose [GO:0033499]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	galactose catabolic process via UDP-galactose [GO:0033499]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d1guqc2_d4zkla___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; galactose catabolic process via UDP-galactose [GO:0033499]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	galactose catabolic process via UDP-galactose [GO:0033499]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d1guqd1_d2q4lb2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; galactose catabolic process via UDP-galactose [GO:0033499]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	galactose catabolic process via UDP-galactose [GO:0033499]	carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]
d1guqd1_d4njzb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; galactose catabolic process via UDP-galactose [GO:0033499]	mitochondrion [GO:0005739]; nucleolus [GO:0005730]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; apoptotic process [GO:0006915]; lipid catabolic process [GO:0016042]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; steroid biosynthetic process [GO:0006694]	galactose catabolic process via UDP-galactose [GO:0033499]	apoptotic process [GO:0006915]; lipid catabolic process [GO:0016042]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; steroid biosynthetic process [GO:0006694]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrion [GO:0005739]; nucleolus [GO:0005730]	ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]
d1gusa__d1h9rb1__1			Firmicutes	Proteobacteria	molybdate ion transport [GO:0015689]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]; molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]		cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]
d1gutc__d1o7ld2__1			Firmicutes	Proteobacteria	molybdate ion transport [GO:0015689]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]; molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]		cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]
d1gutd__d1fr3c___1			Firmicutes	Firmicutes	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]				
d1gutd__d1h9sb1__1			Firmicutes	Proteobacteria	molybdate ion transport [GO:0015689]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]; molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]		cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]
d1gutf__d1h9mb1__1			Firmicutes	Proteobacteria	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]				
d1guva2_d4q7na2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; endochitinase activity [GO:0008843]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; polysaccharide catabolic process [GO:0000272]; polysaccharide digestion [GO:0044245]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	chitin catabolic process [GO:0006032]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; polysaccharide catabolic process [GO:0000272]; polysaccharide digestion [GO:0044245]; response to bacterium [GO:0009617]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]; endochitinase activity [GO:0008843]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]
d1guza2_d1uxjc2__1			Chlorobi	Chloroflexi	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-malate dehydrogenase activity [GO:0030060]
d1guzc1_d3vpxa2__1			Chlorobi	Firmicutes	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cellular amino acid metabolic process [GO:0006520]			L-malate dehydrogenase activity [GO:0030060]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1gv0a2_d4uulb2__1			Chlorobi		L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]			L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]; nucleotide binding [GO:0000166]
d1gv1d2_d3pqdh2__1			Chlorobi	Firmicutes	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d1gv3a1_d4guni1__1		Fungi	Cyanobacteria	Ascomycota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gv3a2_d4gunn2__1		Fungi	Cyanobacteria	Ascomycota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gv3b1_d3kkya1__1			Cyanobacteria	Deinococcus-Thermus	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gv3b1_d4l2cb1__1			Cyanobacteria	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1gv4a3_d1onfa3__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; DNA binding [GO:0003677]; electron-transferring-flavoprotein dehydrogenase activity [GO:0004174]; FAD binding [GO:0071949]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H [GO:0016651]; protein dimerization activity [GO:0046983]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic mitochondrial changes [GO:0008637]; apoptotic process [GO:0006915]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; cell redox homeostasis [GO:0045454]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic mitochondrial changes [GO:0008637]; apoptotic process [GO:0006915]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cell [GO:0005623]; cytoplasm [GO:0005737]	DNA binding [GO:0003677]; electron-transferring-flavoprotein dehydrogenase activity [GO:0004174]; FAD binding [GO:0071949]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H [GO:0016651]; protein dimerization activity [GO:0046983]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]
d1gv4b2_d1grea2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; DNA binding [GO:0003677]; electron-transferring-flavoprotein dehydrogenase activity [GO:0004174]; FAD binding [GO:0071949]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H [GO:0016651]; protein dimerization activity [GO:0046983]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic mitochondrial changes [GO:0008637]; apoptotic process [GO:0006915]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic mitochondrial changes [GO:0008637]; apoptotic process [GO:0006915]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	DNA binding [GO:0003677]; electron-transferring-flavoprotein dehydrogenase activity [GO:0004174]; FAD binding [GO:0071949]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H [GO:0016651]; protein dimerization activity [GO:0046983]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]
d1gv7a__d4rska___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1gvca__d2dbpa___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]		ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]	
d1gvca__d3skpa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	metal ion binding [GO:0046872]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d1gvea__d5c7ha___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; aldo-keto reductase (NADP) activity [GO:0004033]; identical protein binding [GO:0042802]; aflatoxin catabolic process [GO:0046223]; aflatoxin metabolic process [GO:0046222]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	aflatoxin catabolic process [GO:0046223]; aflatoxin metabolic process [GO:0046222]		cytosol [GO:0005829]		aldo-keto reductase (NADP) activity [GO:0004033]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1gvha1_d5aqdi___1			Proteobacteria	Cyanobacteria	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; heme binding [GO:0020037]; hydroperoxide reductase activity [GO:0032843]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular response to nitrosative stress [GO:0071500]; nitric oxide catabolic process [GO:0046210]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular response to nitrosative stress [GO:0071500]; nitric oxide catabolic process [GO:0046210]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; heme binding [GO:0020037]; hydroperoxide reductase activity [GO:0032843]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1gvha3_d1cqxb3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; heme binding [GO:0020037]; hydroperoxide reductase activity [GO:0032843]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular response to nitrosative stress [GO:0071500]; nitric oxide catabolic process [GO:0046210]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	cellular response to nitrosative stress [GO:0071500]; nitric oxide catabolic process [GO:0046210]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; heme binding [GO:0020037]; hydroperoxide reductase activity [GO:0032843]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1gvia2_d1dtua3__1			Deinococcus-Thermus	Firmicutes	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1gvia3_d1c0db___1			Deinococcus-Thermus		alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]	
d1gvib1_d2fhfa1__1			Deinococcus-Thermus	Proteobacteria	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		plasma membrane [GO:0005886]	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]
d1gvib2_d4jcma2__1			Deinococcus-Thermus	Firmicutes	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; starch binding [GO:2001070]; transferase activity [GO:0016740]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]	metal ion binding [GO:0046872]; starch binding [GO:2001070]; transferase activity [GO:0016740]
d1gvib3_d1vffa1__1			Deinococcus-Thermus	Euryarchaeota	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1gvib3_d4do4a1__1		Metazoa	Deinococcus-Thermus	Chordata	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d1gvja__d1etca___1	Metazoa		Chordata		cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]		angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]		cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]		DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	
d1gvjb__d1ldkb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cell [GO:0005623]; cullin-RING ubiquitin ligase complex [GO:0031461]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; SCF ubiquitin ligase complex [GO:0019005]; ubiquitin protein ligase binding [GO:0031625]; animal organ morphogenesis [GO:0009887]; cell population proliferation [GO:0008283]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; interleukin-1-mediated signaling pathway [GO:0070498]; intrinsic apoptotic signaling pathway [GO:0097193]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	animal organ morphogenesis [GO:0009887]; cell population proliferation [GO:0008283]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; interleukin-1-mediated signaling pathway [GO:0070498]; intrinsic apoptotic signaling pathway [GO:0097193]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cullin-RING ubiquitin ligase complex [GO:0031461]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; SCF ubiquitin ligase complex [GO:0019005]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	ubiquitin protein ligase binding [GO:0031625]
d1gvkb__d1exfa___1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]
d1gvla__d2ztxa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]; serine-type endopeptidase activity [GO:0004252]; amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host gene expression [GO:0039656]; modulation by virus of host NIK/NF-kappaB signaling [GO:0061765]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive regulation by virus of host cytokine production [GO:0044832]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host gene expression [GO:0039656]; modulation by virus of host NIK/NF-kappaB signaling [GO:0061765]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive regulation by virus of host cytokine production [GO:0044832]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1gvla__d3mwiu___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]; serine-type endopeptidase activity [GO:0004252]; amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1gvoa__d3n19d___1			Proteobacteria	Proteobacteria	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d1gvqa__d2e77b___1			Proteobacteria	Firmicutes	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d1gvza__d4x6oa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; secretory granule [GO:0030141]; serine-type endopeptidase activity [GO:0004252]; regulation of systemic arterial blood pressure [GO:0003073]; zymogen activation [GO:0031638]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	regulation of systemic arterial blood pressure [GO:0003073]; zymogen activation [GO:0031638]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d1gw0a1_d1aznd___1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	oxidation-reduction process [GO:0055114]	extraorganismal space [GO:0043245]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1gw0b1_d3sbpd2__1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	extraorganismal space [GO:0043245]	membrane [GO:0016020]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d1gw0b3_d5d4jc2__1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	extraorganismal space [GO:0043245]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1gw2a__d5sx6b2__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1gwba__d2wfha___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; thrombin-activated receptor activity [GO:0015057]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; GTPase inhibitor activity [GO:0005095]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; laminin-1 binding [GO:0043237]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; Roundabout binding [GO:0048495]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; cellular response to hormone stimulus [GO:0032870]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; induction of negative chemotaxis [GO:0050929]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; pulmonary valve morphogenesis [GO:0003184]; response to cortisol [GO:0051414]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; cellular response to hormone stimulus [GO:0032870]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; induction of negative chemotaxis [GO:0050929]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; pulmonary valve morphogenesis [GO:0003184]; response to cortisol [GO:0051414]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	thrombin-activated receptor activity [GO:0015057]	calcium ion binding [GO:0005509]; GTPase inhibitor activity [GO:0005095]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; laminin-1 binding [GO:0043237]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; Roundabout binding [GO:0048495]
d1gwcb1_d1vf3a2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1gwcb2_d5myea1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	glutathione transferase activity [GO:0004364]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; protein glutathionylation [GO:0010731]		protein glutathionylation [GO:0010731]			glutathione transferase activity [GO:0004364]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]
d1gwcc2_d1oc8b___1	Viridiplantae		Streptophyta		glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]	glutathione transferase activity [GO:0004364]	
d1gwda__d4w56a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gwla__d2wuha___1	Fungi	Metazoa	Chytridiomycota	Chordata		actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; collagen binding [GO:0005518]; protein tyrosine kinase collagen receptor activity [GO:0038062]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; biomineral tissue development [GO:0031214]; cell adhesion [GO:0007155]; chondrocyte proliferation [GO:0035988]; collagen fibril organization [GO:0030199]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endochondral bone growth [GO:0003416]; extracellular matrix organization [GO:0030198]; ossification [GO:0001503]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase activity [GO:0045860]; protein autophosphorylation [GO:0046777]; regulation of bone mineralization [GO:0030500]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of tissue remodeling [GO:0034103]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		biomineral tissue development [GO:0031214]; cell adhesion [GO:0007155]; chondrocyte proliferation [GO:0035988]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; collagen fibril organization [GO:0030199]; endochondral bone growth [GO:0003416]; extracellular matrix organization [GO:0030198]; ossification [GO:0001503]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase activity [GO:0045860]; protein autophosphorylation [GO:0046777]; regulation of bone mineralization [GO:0030500]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of tissue remodeling [GO:0034103]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; collagen binding [GO:0005518]; protein tyrosine kinase collagen receptor activity [GO:0038062]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1gwoa__d1aeba___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; vacuole [GO:0005773]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1gwta1_d1fhfb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]	extracellular region [GO:0005576]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1gwta1_d5sxtb1__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1gwya__d1iazb___1	Metazoa	Metazoa	Cnidaria	Cnidaria	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]	cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]	cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]	channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	channel activity [GO:0015267]; toxin activity [GO:0090729]
d1gx0a__d1vzxa___1	Metazoa	Metazoa	Chordata	Chordata	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d1gx0b__d2bo4e___1	Metazoa		Chordata	Bacteroidetes	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]; mannosylglycerate biosynthetic process [GO:0051479]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	mannosylglycerate biosynthetic process [GO:0051479]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]		metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]	identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]
d1gx3d__d4bgfh___1			Actinobacteria		arylamine N-acetyltransferase activity [GO:0004060]						arylamine N-acetyltransferase activity [GO:0004060]	
d1gx8a__d1icma___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]		fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]	extracellular region [GO:0005576]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1gx9a__d5urad1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cell periphery [GO:0071944]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; lipid binding [GO:0008289]; cell proliferation in forebrain [GO:0021846]; epithelial cell proliferation [GO:0050673]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]; triglyceride catabolic process [GO:0019433]		cell proliferation in forebrain [GO:0021846]; epithelial cell proliferation [GO:0050673]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	cell-cell junction [GO:0005911]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	lipid binding [GO:0008289]
d1gxaa__d5l8ob___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; lipid binding [GO:0008289]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; negative regulation of cell population proliferation [GO:0008285]; triglyceride catabolic process [GO:0019433]		lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; negative regulation of cell population proliferation [GO:0008285]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	lipid binding [GO:0008289]
d1gxba1_d1kgzb1__1			Crenarchaeota	Proteobacteria	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	tryptophan biosynthetic process [GO:0000162]	tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]		anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]
d1gxbd2_d2wk6a2__1		Metazoa	Crenarchaeota	Chordata	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	tryptophan biosynthetic process [GO:0000162]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	cytosol [GO:0005829]	cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1gxca__d1k2ma___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625]; cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic DNA damage checkpoint [GO:0044773]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; replicative senescence [GO:0090399]; response to glycoside [GO:1903416]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic DNA damage checkpoint [GO:0044773]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; replicative senescence [GO:0090399]; response to glycoside [GO:1903416]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]	deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]
d1gxcd__d1yjmb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625]; cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic DNA damage checkpoint [GO:0044773]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; replicative senescence [GO:0090399]; response to glycoside [GO:1903416]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]	mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; double-stranded DNA binding [GO:0003690]; nucleoside monophosphate kinase activity [GO:0050145]; polynucleotide 3'-phosphatase activity [GO:0046403]; dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide phosphorylation [GO:0046939]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]	cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic DNA damage checkpoint [GO:0044773]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; replicative senescence [GO:0090399]; response to glycoside [GO:1903416]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]	dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide phosphorylation [GO:0046939]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; double-stranded DNA binding [GO:0003690]; nucleoside monophosphate kinase activity [GO:0050145]; polynucleotide 3'-phosphatase activity [GO:0046403]
d1gxcg__d1khud___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625]; cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic DNA damage checkpoint [GO:0044773]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; replicative senescence [GO:0090399]; response to glycoside [GO:1903416]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; nuclear chromatin [GO:0000790]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]; co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [GO:0030618]; BMP signaling pathway [GO:0030509]; embryonic pattern specification [GO:0009880]; positive regulation of gene expression [GO:0010628]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; primary miRNA processing [GO:0031053]; protein deubiquitination [GO:0016579]; signal transduction [GO:0007165]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic DNA damage checkpoint [GO:0044773]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; replicative senescence [GO:0090399]; response to glycoside [GO:1903416]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]	BMP signaling pathway [GO:0030509]; embryonic pattern specification [GO:0009880]; positive regulation of gene expression [GO:0010628]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; primary miRNA processing [GO:0031053]; protein deubiquitination [GO:0016579]; signal transduction [GO:0007165]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; nuclear chromatin [GO:0000790]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625]	co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [GO:0030618]
d1gxdb2_d3c7xa___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; intermediate filament cytoskeleton [GO:0045111]; macropinosome [GO:0044354]; melanosome [GO:0042470]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; metalloaminopeptidase activity [GO:0070006]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; astrocyte cell migration [GO:0043615]; branching morphogenesis of an epithelial tube [GO:0048754]; cell motility [GO:0048870]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; endodermal cell differentiation [GO:0035987]; endothelial cell proliferation [GO:0001935]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; head development [GO:0060322]; lung development [GO:0030324]; male gonad development [GO:0008584]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle development [GO:0001541]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of macrophage migration [GO:1905523]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein processing [GO:0010954]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein localization to plasma membrane [GO:1903076]; response to estrogen [GO:0043627]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to odorant [GO:1990834]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; skeletal system development [GO:0001501]; tissue remodeling [GO:0048771]; zymogen activation [GO:0031638]	angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	angiogenesis [GO:0001525]; astrocyte cell migration [GO:0043615]; branching morphogenesis of an epithelial tube [GO:0048754]; cell motility [GO:0048870]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; endodermal cell differentiation [GO:0035987]; endothelial cell proliferation [GO:0001935]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; head development [GO:0060322]; lung development [GO:0030324]; male gonad development [GO:0008584]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle development [GO:0001541]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of macrophage migration [GO:1905523]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein processing [GO:0010954]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein localization to plasma membrane [GO:1903076]; response to estrogen [GO:0043627]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to odorant [GO:1990834]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; skeletal system development [GO:0001501]; tissue remodeling [GO:0048771]; zymogen activation [GO:0031638]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; intermediate filament cytoskeleton [GO:0045111]; macropinosome [GO:0044354]; melanosome [GO:0042470]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; metalloaminopeptidase activity [GO:0070006]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1gxea__d1d5ma1__1	Metazoa	Metazoa	Chordata	Chordata	A band [GO:0031672]; C zone [GO:0014705]; cardiac myofibril [GO:0097512]; cytosol [GO:0005829]; sarcomere [GO:0030017]; striated muscle myosin thick filament [GO:0005863]; actin binding [GO:0003779]; ATPase activator activity [GO:0001671]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; myosin heavy chain binding [GO:0032036]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	A band [GO:0031672]; cardiac myofibril [GO:0097512]; cytosol [GO:0005829]; C zone [GO:0014705]; sarcomere [GO:0030017]; striated muscle myosin thick filament [GO:0005863]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	actin binding [GO:0003779]; ATPase activator activity [GO:0001671]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; myosin heavy chain binding [GO:0032036]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d1gxla__d1gxjb___1			Thermotogae	Thermotogae	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; chromosome condensation [GO:0030261]; DNA replication [GO:0006260]; sister chromatid cohesion [GO:0007062]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; chromosome condensation [GO:0030261]; DNA replication [GO:0006260]; sister chromatid cohesion [GO:0007062]	chromosome condensation [GO:0030261]; DNA replication [GO:0006260]; sister chromatid cohesion [GO:0007062]	chromosome condensation [GO:0030261]; DNA replication [GO:0006260]; sister chromatid cohesion [GO:0007062]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]
d1gxoa__d1gxmb1__1			Proteobacteria	Proteobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; lyase activity [GO:0016829]; polysaccharide binding [GO:0030247]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; lyase activity [GO:0016829]; polysaccharide binding [GO:0030247]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; lyase activity [GO:0016829]; polysaccharide binding [GO:0030247]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; lyase activity [GO:0016829]; polysaccharide binding [GO:0030247]
d1gxpe__d2hqna1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding [GO:0003677]
d1gxs.1_d1ysca___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	hydroxymandelonitrile lyase activity [GO:0050419]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; fungal-type vacuole [GO:0000324]; fungal-type vacuole lumen [GO:0000328]; serine-type carboxypeptidase activity [GO:0004185]; macroautophagy [GO:0016236]; phytochelatin biosynthetic process [GO:0046938]; protein catabolic process in the vacuole [GO:0007039]; proteolysis involved in cellular protein catabolic process [GO:0051603]; zymogen activation [GO:0031638]		macroautophagy [GO:0016236]; phytochelatin biosynthetic process [GO:0046938]; protein catabolic process in the vacuole [GO:0007039]; proteolysis involved in cellular protein catabolic process [GO:0051603]; zymogen activation [GO:0031638]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; fungal-type vacuole [GO:0000324]; fungal-type vacuole lumen [GO:0000328]	hydroxymandelonitrile lyase activity [GO:0050419]	serine-type carboxypeptidase activity [GO:0004185]
d1gxs.2_d3d2cd___1	Viridiplantae		Streptophyta	Firmicutes	hydroxymandelonitrile lyase activity [GO:0050419]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	hydroxymandelonitrile lyase activity [GO:0050419]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d1gxta__d1x0pc___1			Proteobacteria	Cyanobacteria	carboxyl- or carbamoyltransferase activity [GO:0016743]; double-stranded RNA binding [GO:0003725]; ligase activity [GO:0016874]; zinc ion binding [GO:0008270]; protein carbamoylation [GO:0046944]; protein maturation [GO:0051604]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	protein carbamoylation [GO:0046944]; protein maturation [GO:0051604]				carboxyl- or carbamoyltransferase activity [GO:0016743]; double-stranded RNA binding [GO:0003725]; ligase activity [GO:0016874]; zinc ion binding [GO:0008270]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]
d1gxua__d2byca1__1			Proteobacteria		carboxyl- or carbamoyltransferase activity [GO:0016743]; double-stranded RNA binding [GO:0003725]; ligase activity [GO:0016874]; zinc ion binding [GO:0008270]; protein carbamoylation [GO:0046944]; protein maturation [GO:0051604]		protein carbamoylation [GO:0046944]; protein maturation [GO:0051604]				carboxyl- or carbamoyltransferase activity [GO:0016743]; double-stranded RNA binding [GO:0003725]; ligase activity [GO:0016874]; zinc ion binding [GO:0008270]	
d1gxv2__d4ekqb1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gxxa__d1b5ua___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1gxxa__d3cdqa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1gxya__d4h0ta2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of plasma membrane [GO:0046658]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; NAD glycohydrolase activity [GO:0061810]; NAD(P)+-protein-arginine ADP-ribosyltransferase activity [GO:0003956]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD catabolic process [GO:0019677]; peptidyl-arginine ADP-ribosylation [GO:0018120]; protein ADP-ribosylation [GO:0006471]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	NAD catabolic process [GO:0019677]; peptidyl-arginine ADP-ribosylation [GO:0018120]; protein ADP-ribosylation [GO:0006471]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	anchored component of plasma membrane [GO:0046658]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; NAD(P)+-protein-arginine ADP-ribosyltransferase activity [GO:0003956]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD glycohydrolase activity [GO:0061810]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d1gxyb__d4r6ea2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of plasma membrane [GO:0046658]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; NAD glycohydrolase activity [GO:0061810]; NAD(P)+-protein-arginine ADP-ribosyltransferase activity [GO:0003956]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD catabolic process [GO:0019677]; peptidyl-arginine ADP-ribosylation [GO:0018120]; protein ADP-ribosylation [GO:0006471]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	NAD catabolic process [GO:0019677]; peptidyl-arginine ADP-ribosylation [GO:0018120]; protein ADP-ribosylation [GO:0006471]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	anchored component of plasma membrane [GO:0046658]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; NAD(P)+-protein-arginine ADP-ribosyltransferase activity [GO:0003956]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD glycohydrolase activity [GO:0061810]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1gy1a__d3nt0a2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d1gy1b__d2ppfc2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1gy2a__d2fjsa2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1gy3b2_d4ii5d1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1gy3d2_d4cxab1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cyclin K-CDK12 complex [GO:0002944]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin K-CDK12 complex [GO:0002944]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]
d1gy6a__d4l7kj___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]		identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	steroid delta-isomerase activity [GO:0004769]
d1gy7a__d2yflf___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nuclear envelope [GO:0005635]; nuclear pore central transport channel [GO:0044613]; Ran GTPase binding [GO:0008536]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]	aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]; nuclear envelope [GO:0005635]; nuclear pore central transport channel [GO:0044613]		Ran GTPase binding [GO:0008536]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1gy7b__d5jpub___1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; nuclear envelope [GO:0005635]; nuclear pore central transport channel [GO:0044613]; Ran GTPase binding [GO:0008536]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]	limonene-1,2-epoxide hydrolase activity [GO:0018744]	nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]		cytoplasm [GO:0005737]; nuclear envelope [GO:0005635]; nuclear pore central transport channel [GO:0044613]		Ran GTPase binding [GO:0008536]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d1gyaa__d4ouul2__1	Metazoa		Chordata		anchored component of plasma membrane [GO:0046658]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; membrane raft polarization [GO:0001766]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of T cell differentiation [GO:0045580]; T cell activation [GO:0042110]		apoptotic process [GO:0006915]; cell-cell adhesion [GO:0098609]; cell surface receptor signaling pathway [GO:0007166]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; membrane raft polarization [GO:0001766]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of T cell differentiation [GO:0045580]; T cell activation [GO:0042110]		anchored component of plasma membrane [GO:0046658]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]	
d1gyca1_d3rymc___1	Fungi		Basidiomycota	Proteobacteria	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	lignin catabolic process [GO:0046274]		extracellular region [GO:0005576]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1gydb__d2exhc2__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	arabinan catabolic process [GO:0031222]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1gyeb__d5ayeb___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	arabinan catabolic process [GO:0031222]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]		alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]	transferase activity, transferring glycosyl groups [GO:0016757]
d1gyha__d3cu9a___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	cytoplasm [GO:0005737]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	arabinan catabolic process [GO:0031222]	arabinan catabolic process [GO:0031222]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]	arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]
d1gyha__d3om7b___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]	arabinan catabolic process [GO:0031222]	carbohydrate utilization [GO:0009758]	extracellular region [GO:0005576]		alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]
d1gyhb__d1y9ga2__1		Fungi	Proteobacteria	Ascomycota	extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	extracellular region [GO:0005576]; fructan beta-fructosidase activity [GO:0051669]; polysaccharide catabolic process [GO:0000272]	arabinan catabolic process [GO:0031222]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]	fructan beta-fructosidase activity [GO:0051669]
d1gyhe__d3om4a___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]	arabinan catabolic process [GO:0031222]	carbohydrate utilization [GO:0009758]	extracellular region [GO:0005576]		alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]
d1gyhf__d2exja2__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	arabinan catabolic process [GO:0031222]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1gyhf__d4udje___1			Proteobacteria		extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]		arabinan catabolic process [GO:0031222]		extracellular region [GO:0005576]		alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]	
d1gyka__d1g8wc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	mannose binding [GO:0005537]; toxin activity [GO:0090729]; defense response [GO:0006952]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	defense response [GO:0006952]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	mannose binding [GO:0005537]; toxin activity [GO:0090729]
d1gykc__d4ygdg___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; calcium ion binding [GO:0005509]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	calcium ion binding [GO:0005509]
d1gykd__d1b09b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1gyke__d4ga9b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of viral entry into host cell [GO:0046598]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of viral entry into host cell [GO:0046598]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]
d1gylb__d4utia___1	Viridiplantae		Streptophyta	Proteobacteria	peroxisome [GO:0005777]; FMN binding [GO:0010181]; long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity [GO:0052853]; medium-chain-(S)-2-hydroxy-acid oxidase activity [GO:0052854]; very-long-chain-(S)-2-hydroxy-acid oxidase activity [GO:0052852]; oxidative photosynthetic carbon pathway [GO:0009854]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	oxidative photosynthetic carbon pathway [GO:0009854]		peroxisome [GO:0005777]		FMN binding [GO:0010181]; long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity [GO:0052853]; medium-chain-(S)-2-hydroxy-acid oxidase activity [GO:0052854]; very-long-chain-(S)-2-hydroxy-acid oxidase activity [GO:0052852]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d1gypa2_d2hkia2__1		Viridiplantae		Streptophyta	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glycosome [GO:0020015]	chloroplast [GO:0009507]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1gyqc2_d1k5hc3__1				Proteobacteria	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	glycosome [GO:0020015]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]
d1gyrb2_d1qv6a2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	mitochondrion [GO:0005739]	cytosol [GO:0005829]	trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1gyrb2_d2pk3b___1	Fungi		Ascomycota	Firmicutes	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	GDP-4-dehydro-6-deoxy-D-mannose reductase activity [GO:0033705]; oxidation-reduction process [GO:0055114]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	oxidation-reduction process [GO:0055114]	mitochondrion [GO:0005739]		trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]	GDP-4-dehydro-6-deoxy-D-mannose reductase activity [GO:0033705]
d1gytd1_d5cb5g___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]; negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	cytoplasm [GO:0005737]		aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]
d1gyte2_d2ctba___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	proteolysis [GO:0006508]	cytoplasm [GO:0005737]	extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1gytf1_d1blle1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]	aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]
d1gyti2_d1bavd___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	proteolysis [GO:0006508]	cytoplasm [GO:0005737]	extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1gytj1_d5cmsj___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]; negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	cytoplasm [GO:0005737]		aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]
d1gytl1_d2xd7c___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	Barr body [GO:0001740]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]; brain development [GO:0007420]; chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of keratinocyte differentiation [GO:0045618]	peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	brain development [GO:0007420]; chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of keratinocyte differentiation [GO:0045618]	cytoplasm [GO:0005737]	Barr body [GO:0001740]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]
d1gyva__d2iv9a1__1	Metazoa	Metazoa	Chordata	Chordata	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]; collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	AP-2 adaptor complex [GO:0030122]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]; clathrin binding [GO:0030276]; protein-containing complex binding [GO:0044877]; signal sequence binding [GO:0005048]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; coronary vasculature development [GO:0060976]; ephrin receptor signaling pathway [GO:0048013]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; membrane organization [GO:0061024]; negative regulation of neuron death [GO:1901215]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein localization to membrane [GO:1905477]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; regulation of defense response to virus by virus [GO:0050690]; synaptic vesicle endocytosis [GO:0048488]; ventricular septum development [GO:0003281]; vesicle-mediated transport [GO:0016192]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; coronary vasculature development [GO:0060976]; ephrin receptor signaling pathway [GO:0048013]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; membrane organization [GO:0061024]; negative regulation of neuron death [GO:1901215]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein localization to membrane [GO:1905477]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; regulation of defense response to virus by virus [GO:0050690]; synaptic vesicle endocytosis [GO:0048488]; ventricular septum development [GO:0003281]; vesicle-mediated transport [GO:0016192]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]	AP-2 adaptor complex [GO:0030122]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]	collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]	clathrin binding [GO:0030276]; protein-containing complex binding [GO:0044877]; signal sequence binding [GO:0005048]
d1gywb__d1ky7a1__1	Metazoa	Metazoa	Chordata	Chordata	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]; collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]	collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]	clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]
d1gz1a__d1cb2b___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]
d1gz1a__d5jx5b___1	Fungi	Fungi	Ascomycota	Chytridiomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1gz3d2_d1b3bf2__1	Metazoa		Chordata	Thermotogae	intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]; malate metabolic process [GO:0006108]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031]; tricarboxylic acid cycle [GO:0006099]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	malate metabolic process [GO:0006108]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031]; tricarboxylic acid cycle [GO:0006099]	cellular amino acid metabolic process [GO:0006520]	intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d1gz9a__d4ayue___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1gzaa__d1h5ka___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; vacuole [GO:0005773]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1gzaa__d5kqqb2__1	Fungi		Basidiomycota	Proteobacteria	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1gzed__d4gv2a2__1		Metazoa		Chordata	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; catalytic activity [GO:0003824]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	extracellular region [GO:0005576]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]	transferase activity, transferring pentosyl groups [GO:0016763]	catalytic activity [GO:0003824]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]
d1gzfb__d1gira1__1				Firmicutes	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	transferase activity, transferring pentosyl groups [GO:0016763]	nucleotide binding [GO:0000166]
d1gzfd__d1gxza___1		Metazoa		Chordata	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	anchored component of plasma membrane [GO:0046658]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; NAD glycohydrolase activity [GO:0061810]; NAD(P)+-protein-arginine ADP-ribosyltransferase activity [GO:0003956]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD catabolic process [GO:0019677]; peptidyl-arginine ADP-ribosylation [GO:0018120]; protein ADP-ribosylation [GO:0006471]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	NAD catabolic process [GO:0019677]; peptidyl-arginine ADP-ribosylation [GO:0018120]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	anchored component of plasma membrane [GO:0046658]	transferase activity, transferring pentosyl groups [GO:0016763]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; NAD(P)+-protein-arginine ADP-ribosyltransferase activity [GO:0003956]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD glycohydrolase activity [GO:0061810]
d1gzia__d1opsa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]	extracellular region [GO:0005576]			extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1gzja__d1ud8a2__1	Fungi		Ascomycota	Firmicutes	cellulase activity [GO:0008810]; carbohydrate metabolic process [GO:0005975]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			cellulase activity [GO:0008810]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1gzpa1_d1deea1__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	pathogenesis [GO:0009405]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	IgG binding [GO:0019864]
d1gzqa1_d3e3qa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1gzqb2_d1v7ni2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]
d1gzqb2_d4ag4l1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; collagen binding [GO:0005518]; metal ion binding [GO:0046872]; protein tyrosine kinase collagen receptor activity [GO:0038062]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell adhesion [GO:0007155]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; extracellular matrix organization [GO:0030198]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell population proliferation [GO:0008285]; neuron projection extension [GO:1990138]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell migration [GO:0014909]; smooth muscle cell-matrix adhesion [GO:0061302]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell adhesion [GO:0007155]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; extracellular matrix organization [GO:0030198]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell population proliferation [GO:0008285]; neuron projection extension [GO:1990138]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell-matrix adhesion [GO:0061302]; smooth muscle cell migration [GO:0014909]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; collagen binding [GO:0005518]; metal ion binding [GO:0046872]; protein tyrosine kinase collagen receptor activity [GO:0038062]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1gzva__d1n8tb___1	Metazoa	Metazoa	Chordata	Chordata	ciliary membrane [GO:0060170]; cytosol [GO:0005829]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; in utero embryonic development [GO:0001701]; mesoderm formation [GO:0001707]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; in utero embryonic development [GO:0001701]; mesoderm formation [GO:0001707]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	ciliary membrane [GO:0060170]; cytosol [GO:0005829]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]
d1gzva__d1tzcb___1	Metazoa		Chordata	Crenarchaeota	ciliary membrane [GO:0060170]; cytosol [GO:0005829]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; in utero embryonic development [GO:0001701]; mesoderm formation [GO:0001707]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]; carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; in utero embryonic development [GO:0001701]; mesoderm formation [GO:0001707]	carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	ciliary membrane [GO:0060170]; cytosol [GO:0005829]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]
d1gzxa__d3ubcd___1	Metazoa		Chordata	Verrucomicrobia	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1gzxb__d2bkmb___1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d1gzxb__d2hhda___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1gzxd__d1y46b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1h0da1_d1ccza1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; signaling receptor binding [GO:0005102]; cell-cell adhesion [GO:0098609]; cellular response to interferon-gamma [GO:0071346]; cellular response to tumor necrosis factor [GO:0071356]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	cell-cell adhesion [GO:0098609]; cellular response to interferon-gamma [GO:0071346]; cellular response to tumor necrosis factor [GO:0071356]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]	signaling receptor binding [GO:0005102]
d1h0db1_d1ap2a___1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]		actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]	
d1h0db2_d5tp3a1__1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]		actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]	
d1h0dc__d1j81.1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	extracellular region [GO:0005576]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1h0ha1_d4kodj1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (cytochrome-c-553) activity [GO:0047111]; formate dehydrogenase (NAD+) activity [GO:0008863]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; cellular respiration [GO:0045333]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	cellular respiration [GO:0045333]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	periplasmic space [GO:0042597]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (cytochrome-c-553) activity [GO:0047111]; formate dehydrogenase (NAD+) activity [GO:0008863]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1h0hl__d1bc6a___1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (cytochrome-c-553) activity [GO:0047111]; formate dehydrogenase (NAD+) activity [GO:0008863]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; cellular respiration [GO:0045333]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cellular respiration [GO:0045333]		periplasmic space [GO:0042597]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (cytochrome-c-553) activity [GO:0047111]; formate dehydrogenase (NAD+) activity [GO:0008863]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1h0kb2_d1ma0b2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]
d1h0oa__d3hx7u___1	Metazoa		Chordata		cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]		deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]		cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]		ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	
d1h0ya__d1udva___1			Crenarchaeota	Crenarchaeota	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; chromosome condensation [GO:0030261]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	chromosome condensation [GO:0030261]		chromosome [GO:0005694]; cytoplasm [GO:0005737]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]
d1h12a__d5gy0b1__1			Proteobacteria	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			endo-1,4-beta-xylanase activity [GO:0031176]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1h14a__d5gy1a1__1			Proteobacteria	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			endo-1,4-beta-xylanase activity [GO:0031176]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1h15a1_d4xbgd2__1	Metazoa		Chordata		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	
d1h15d1_d1igtc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1h15e1_d2bcke2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1h15e1_d4xceb1__1	Metazoa		Chordata		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	
d1h18a__d3r1rc2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; formate C-acetyltransferase activity [GO:0008861]; glucose metabolic process [GO:0006006]; threonine catabolic process [GO:0006567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	glucose metabolic process [GO:0006006]; threonine catabolic process [GO:0006567]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	formate C-acetyltransferase activity [GO:0008861]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1h19a2_d4homa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1h19a3_d1qica___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1h1aa__d1loa.3__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	mannose binding [GO:0005537]	xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	mannose binding [GO:0005537]
d1h1bb__d4ytaa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; phagocytic vesicle [GO:0045335]; secretory granule [GO:0030141]; specific granule lumen [GO:0035580]; transcriptional repressor complex [GO:0017053]; cytokine binding [GO:0019955]; endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; transcription corepressor activity [GO:0003714]; acute inflammatory response to antigenic stimulus [GO:0002438]; antimicrobial humoral response [GO:0019730]; biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0002812]; cellular calcium ion homeostasis [GO:0006874]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of chemotaxis [GO:0050922]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of fungus [GO:0070947]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of immune response [GO:0050778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; response to UV [GO:0009411]; response to yeast [GO:0001878]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute inflammatory response to antigenic stimulus [GO:0002438]; antimicrobial humoral response [GO:0019730]; biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0002812]; cellular calcium ion homeostasis [GO:0006874]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of chemotaxis [GO:0050922]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of fungus [GO:0070947]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of immune response [GO:0050778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; response to UV [GO:0009411]; response to yeast [GO:0001878]	digestion [GO:0007586]; proteolysis [GO:0006508]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; phagocytic vesicle [GO:0045335]; secretory granule [GO:0030141]; specific granule lumen [GO:0035580]; transcriptional repressor complex [GO:0017053]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytokine binding [GO:0019955]; endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; transcription corepressor activity [GO:0003714]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1h1lc__d4fila___1			Proteobacteria	Firmicutes	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	metal ion binding [GO:0046872]	nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	metal ion binding [GO:0046872]
d1h1oa1_d1m70a2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1h1oa2_d1m6zd1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1h1ob2_d1a2sa___1		Viridiplantae	Proteobacteria	Chlorophyta	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	chloroplast thylakoid lumen [GO:0009543]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]	periplasmic space [GO:0042597]	chloroplast thylakoid lumen [GO:0009543]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1h1sb1_d1unhd___1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	axon [GO:0030424]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; protein kinase 5 complex [GO:0016533]; actin filament binding [GO:0051015]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; ephrin receptor binding [GO:0046875]; ionotropic glutamate receptor binding [GO:0035255]; kinase activity [GO:0016301]; protease binding [GO:0002020]; protein kinase activator activity [GO:0030295]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; brain development [GO:0007420]; cerebellum development [GO:0021549]; embryo development ending in birth or egg hatching [GO:0009792]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; layer formation in cerebral cortex [GO:0021819]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of axon extension [GO:0030517]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of receptor biosynthetic process [GO:0010870]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of macroautophagy [GO:0016241]; regulation of neuron differentiation [GO:0045664]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of synaptic vesicle cycle [GO:0098693]; rhythmic process [GO:0048511]; serine phosphorylation of STAT protein [GO:0042501]; superior olivary nucleus maturation [GO:0021722]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; brain development [GO:0007420]; cerebellum development [GO:0021549]; embryo development ending in birth or egg hatching [GO:0009792]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; layer formation in cerebral cortex [GO:0021819]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of axon extension [GO:0030517]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of receptor biosynthetic process [GO:0010870]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of macroautophagy [GO:0016241]; regulation of neuron differentiation [GO:0045664]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of synaptic vesicle cycle [GO:0098693]; rhythmic process [GO:0048511]; serine phosphorylation of STAT protein [GO:0042501]; superior olivary nucleus maturation [GO:0021722]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	axon [GO:0030424]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; protein kinase 5 complex [GO:0016533]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	actin filament binding [GO:0051015]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; ephrin receptor binding [GO:0046875]; ionotropic glutamate receptor binding [GO:0035255]; kinase activity [GO:0016301]; protease binding [GO:0002020]; protein kinase activator activity [GO:0030295]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]
d1h1ta__d4r0ne___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1h1vg2_d3dawb___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d1h1yb__d2zz1a___1	Viridiplantae		Streptophyta	Euryarchaeota	cytosol [GO:0005829]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]		metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1h24d2_d1c9be2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1h24d2_d1unld___1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	axon [GO:0030424]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; protein kinase 5 complex [GO:0016533]; actin filament binding [GO:0051015]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; ephrin receptor binding [GO:0046875]; ionotropic glutamate receptor binding [GO:0035255]; kinase activity [GO:0016301]; protease binding [GO:0002020]; protein kinase activator activity [GO:0030295]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; brain development [GO:0007420]; cerebellum development [GO:0021549]; embryo development ending in birth or egg hatching [GO:0009792]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; layer formation in cerebral cortex [GO:0021819]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of axon extension [GO:0030517]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of receptor biosynthetic process [GO:0010870]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of macroautophagy [GO:0016241]; regulation of neuron differentiation [GO:0045664]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of synaptic vesicle cycle [GO:0098693]; rhythmic process [GO:0048511]; serine phosphorylation of STAT protein [GO:0042501]; superior olivary nucleus maturation [GO:0021722]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; brain development [GO:0007420]; cerebellum development [GO:0021549]; embryo development ending in birth or egg hatching [GO:0009792]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; layer formation in cerebral cortex [GO:0021819]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of axon extension [GO:0030517]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of receptor biosynthetic process [GO:0010870]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of macroautophagy [GO:0016241]; regulation of neuron differentiation [GO:0045664]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of synaptic vesicle cycle [GO:0098693]; rhythmic process [GO:0048511]; serine phosphorylation of STAT protein [GO:0042501]; superior olivary nucleus maturation [GO:0021722]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	axon [GO:0030424]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; protein kinase 5 complex [GO:0016533]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	actin filament binding [GO:0051015]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; ephrin receptor binding [GO:0046875]; ionotropic glutamate receptor binding [GO:0035255]; kinase activity [GO:0016301]; protease binding [GO:0002020]; protein kinase activator activity [GO:0030295]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]
d1h25d2_d1o9kb___1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]; androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d1h26b2_d3poma2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]; androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d1h27d2_d1tfba2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1h28b1_d1pkdb2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1h28d1_d4bcjb1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1h2ba2_d1b8va1__1			Crenarchaeota	Proteobacteria	alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]			alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	L-malate dehydrogenase activity [GO:0030060]
d1h2ba2_d1dehb2__1		Metazoa	Crenarchaeota	Chordata	alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1h2bb2_d1agnd2__1		Metazoa	Crenarchaeota	Chordata	alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; plasma membrane [GO:0005886]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1h2ea__d1dkoa___1			Firmicutes	Proteobacteria		outer membrane-bounded periplasmic space [GO:0030288]; 4-phytase activity [GO:0008707]; acid phosphatase activity [GO:0003993]; inositol phosphate phosphatase activity [GO:0052745]; nucleotidase activity [GO:0008252]; sugar-phosphatase activity [GO:0050308]; cellular response to anoxia [GO:0071454]; cellular response to phosphate starvation [GO:0016036]; dephosphorylation [GO:0016311]; myo-inositol hexakisphosphate dephosphorylation [GO:0033518]		cellular response to anoxia [GO:0071454]; cellular response to phosphate starvation [GO:0016036]; dephosphorylation [GO:0016311]; myo-inositol hexakisphosphate dephosphorylation [GO:0033518]		outer membrane-bounded periplasmic space [GO:0030288]		4-phytase activity [GO:0008707]; acid phosphatase activity [GO:0003993]; inositol phosphate phosphatase activity [GO:0052745]; nucleotidase activity [GO:0008252]; sugar-phosphatase activity [GO:0050308]
d1h2ia__d2z4me2__1	Metazoa		Chordata		nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]		cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]		nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]		DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]	
d1h2ih__d1yyob2__1	Metazoa		Chordata	Aquificae	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	cytoplasm [GO:0005737]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]; mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]	double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]
d1h2ij__d1j5ee2__1	Metazoa		Chordata	Deinococcus-Thermus	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	translation [GO:0006412]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]	ribosome [GO:0005840]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1h2ik__d5jrbc___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]
d1h2ip__d1yyoa2__1	Metazoa		Chordata	Aquificae	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	cytoplasm [GO:0005737]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]; mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]	double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]
d1h2iv__d1qu6a1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; eukaryotic translation initiation factor 2alpha kinase activity [GO:0004694]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein phosphatase regulator activity [GO:0019888]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723]; activation of MAPKK activity [GO:0000186]; cellular response to amino acid starvation [GO:0034198]; defense response to virus [GO:0051607]; endoplasmic reticulum unfolded protein response [GO:0030968]; evasion or tolerance by virus of host immune response [GO:0030683]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of translation [GO:0017148]; negative regulation of viral genome replication [GO:0045071]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of NLRP3 inflammasome complex assembly [GO:1900225]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; translation [GO:0006412]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	activation of MAPKK activity [GO:0000186]; cellular response to amino acid starvation [GO:0034198]; defense response to virus [GO:0051607]; endoplasmic reticulum unfolded protein response [GO:0030968]; evasion or tolerance by virus of host immune response [GO:0030683]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of translation [GO:0017148]; negative regulation of viral genome replication [GO:0045071]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of NLRP3 inflammasome complex assembly [GO:1900225]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; translation [GO:0006412]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; eukaryotic translation initiation factor 2alpha kinase activity [GO:0004694]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein phosphatase regulator activity [GO:0019888]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723]
d1h2tz__d2mzra1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; post-mRNA release spliceosomal complex [GO:0071014]; ribonucleoprotein complex [GO:1990904]; chromatin binding [GO:0003682]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; nuclear mRNA surveillance [GO:0071028]; poly(A)+ mRNA export from nucleus [GO:0016973]; regulation of mRNA stability involved in response to oxidative stress [GO:2000815]	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	nuclear mRNA surveillance [GO:0071028]; poly(A)+ mRNA export from nucleus [GO:0016973]; regulation of mRNA stability involved in response to oxidative stress [GO:2000815]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; post-mRNA release spliceosomal complex [GO:0071014]; ribonucleoprotein complex [GO:1990904]	mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]	chromatin binding [GO:0003682]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1h2ua2_d2kztb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; BMP signaling pathway [GO:0030509]; cell aging [GO:0007569]; cellular response to lipopolysaccharide [GO:0071222]; epithelial to mesenchymal transition involved in cardiac fibroblast development [GO:0060940]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of inflammatory response [GO:0050729]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; regulation of protein metabolic process [GO:0051246]	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	apoptotic process [GO:0006915]; BMP signaling pathway [GO:0030509]; cell aging [GO:0007569]; cellular response to lipopolysaccharide [GO:0071222]; epithelial to mesenchymal transition involved in cardiac fibroblast development [GO:0060940]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of inflammatory response [GO:0050729]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; regulation of protein metabolic process [GO:0051246]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]	RNA binding [GO:0003723]
d1h2ub1_d3dw8d2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]	mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]	GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]
d1h2xa1_d2hu8b1__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type peptidase activity [GO:0008236]
d1h2xa2_d1uk7a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	hydrolase activity [GO:0016787]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	hydrolase activity [GO:0016787]
d1h31e1_d1i8pb___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]			electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1h32a1_d1e8ea___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1h36a2_d5ilha1__1		Viridiplantae	Firmicutes	Streptophyta	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	hopanoid biosynthetic process [GO:0019746]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d1h37a2_d1n4qb___1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1h37b2_d1n4pf___1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1h3ab2_d5eata1__1		Viridiplantae	Firmicutes	Streptophyta	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	hopanoid biosynthetic process [GO:0019746]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d1h3bb2_d4gtob___1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1h3cb2_d4onta1__1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	hopanoid biosynthetic process [GO:0019746]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d1h3da1_d5ns9b___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	histidine biosynthetic process [GO:0000105]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cytosol [GO:0005829]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1h3ib2_d5ww0a___1	Metazoa	Fungi	Chordata	Ascomycota	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; histone-lysine N-methyltransferase activity [GO:0018024]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; heterochromatin organization [GO:0070828]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of histone H3-K9 methylation [GO:0051570]; response to ethanol [GO:0045471]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; histone methyltransferase activity (H3-K37 specific) [GO:0062122]; histone H3-K36 methylation [GO:0010452]; histone lysine methylation [GO:0034968]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; heterochromatin organization [GO:0070828]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of histone H3-K9 methylation [GO:0051570]; response to ethanol [GO:0045471]	histone H3-K36 methylation [GO:0010452]; histone lysine methylation [GO:0034968]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; histone-lysine N-methyltransferase activity [GO:0018024]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]	histone methyltransferase activity (H3-K37 specific) [GO:0062122]
d1h3lb__d4g7hf1__1			Actinobacteria	Deinococcus-Thermus	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]; DNA-templated transcription, initiation [GO:0006352]; response to oxidative stress [GO:0006979]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	DNA-templated transcription, initiation [GO:0006352]; response to oxidative stress [GO:0006979]	transcription, DNA-templated [GO:0006351]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d1h3na2_d1wk8a___1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; leucine-tRNA ligase activity [GO:0004823]; metal ion binding [GO:0046872]; leucyl-tRNA aminoacylation [GO:0006429]	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; isoleucyl-tRNA aminoacylation [GO:0006428]	leucyl-tRNA aminoacylation [GO:0006429]	isoleucyl-tRNA aminoacylation [GO:0006428]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; leucine-tRNA ligase activity [GO:0004823]; metal ion binding [GO:0046872]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1h3ph1_d1ggbh1__1	Metazoa	Metazoa	Chordata	Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1h3pl1_d1fzka1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1h3ta2_d4nrzb1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1h3ua2_d4lkca2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1h3ub1_d1q9wb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1h3va1_d2vlle2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1h3vb2_d1m4ka1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; transmembrane signaling receptor activity [GO:0004888]; immune response [GO:0006955]; innate immune response [GO:0045087]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	immune response [GO:0006955]; innate immune response [GO:0045087]; regulation of immune response [GO:0050776]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	transmembrane signaling receptor activity [GO:0004888]
d1h3wm2_d5dd6l2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1h3xa1_d1nmcc___1	Metazoa		Chordata	Negarnaviricota	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1h3ya1_d2nw2b1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1h3ya2_d3t77a2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	immune response [GO:0006955]; immunoglobulin production [GO:0002377]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d1h3yb2_d2xqyk1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; fusion of virus membrane with host plasma membrane [GO:0019064]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	fusion of virus membrane with host plasma membrane [GO:0019064]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1h42a1_d4af7b1__1		Viridiplantae	Cyanobacteria	Streptophyta	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	photosynthesis [GO:0015979]	phycobilisome [GO:0030089]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]
d1h42a2_d3w2ia2__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]	oxidation-reduction process [GO:0055114]	cholesterol biosynthetic process [GO:0006695]	phycobilisome [GO:0030089]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1h43a__d1eu8a___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	plasma membrane [GO:0005886]; carbohydrate transport [GO:0008643]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	carbohydrate transport [GO:0008643]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	plasma membrane [GO:0005886]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	
d1h44a__d1lcta___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d1h46x__d3ovwa___1	Fungi	Fungi	Basidiomycota	Ascomycota	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulase activity [GO:0008810]
d1h48d1_d3f0fb___1			Proteobacteria	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d1h4da__d1hjla___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]; bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]; bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]	bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]	bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]
d1h4fa2_d4ls6b1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1h4fb2_d4c6wb1__1			Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	
d1h4fd1_d2ahba1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d1h4hc__d2zaaa1__1			Firmicutes	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	lyase activity [GO:0016829]	xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	lyase activity [GO:0016829]
d1h4hd__d5ocqa___1			Firmicutes	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	periplasmic space [GO:0042597]; kappa-carrageenase activity [GO:0033918]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]		periplasmic space [GO:0042597]	endo-1,4-beta-xylanase activity [GO:0031176]	kappa-carrageenase activity [GO:0033918]
d1h4ia__d2ad8a___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol metabolic process [GO:0015945]	plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol oxidation [GO:0015946]	methanol metabolic process [GO:0015945]	methanol oxidation [GO:0015946]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	plasma membrane [GO:0005886]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]
d1h4jc__d1eeeb___1			Proteobacteria		outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol metabolic process [GO:0015945]		methanol metabolic process [GO:0015945]		outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]		2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]	
d1h4je__d4tqoe___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol metabolic process [GO:0015945]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; alcohol dehydrogenase (acceptor) activity [GO:0018468]; calcium ion binding [GO:0005509]; methanol oxidation [GO:0015946]; oxidation-reduction process [GO:0055114]	methanol metabolic process [GO:0015945]	methanol oxidation [GO:0015946]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]	alcohol dehydrogenase (acceptor) activity [GO:0018468]; calcium ion binding [GO:0005509]
d1h4jg__d4tqof___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol metabolic process [GO:0015945]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; alcohol dehydrogenase (acceptor) activity [GO:0018468]; calcium ion binding [GO:0005509]; methanol oxidation [GO:0015946]; oxidation-reduction process [GO:0055114]	methanol metabolic process [GO:0015945]	methanol oxidation [GO:0015946]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]	alcohol dehydrogenase (acceptor) activity [GO:0018468]; calcium ion binding [GO:0005509]
d1h4kx1_d4wh7a___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; thiosulfate sulfurtransferase activity [GO:0004792]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]		cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	cytoplasm [GO:0005737]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	thiosulfate sulfurtransferase activity [GO:0004792]	phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]
d1h4mx1_d2uzqf2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; thiosulfate sulfurtransferase activity [GO:0004792]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]		cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	cytoplasm [GO:0005737]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	thiosulfate sulfurtransferase activity [GO:0004792]	phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]
d1h4mx2_d1cwra___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; thiosulfate sulfurtransferase activity [GO:0004792]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]		cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	cytoplasm [GO:0005737]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	thiosulfate sulfurtransferase activity [GO:0004792]	phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]
d1h4na__d5tv3h___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1h4oc__d3v1wa2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of store-operated calcium channel activity [GO:1901341]; protein polymerization [GO:0051258]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of store-operated calcium entry [GO:2001256]; sarcomere organization [GO:0045214]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of store-operated calcium channel activity [GO:1901341]; protein polymerization [GO:0051258]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of store-operated calcium entry [GO:2001256]; sarcomere organization [GO:0045214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]	calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]
d1h4od__d1n8je___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cell [GO:0005623]; cytosol [GO:0005829]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]	thioredoxin peroxidase activity [GO:0008379]
d1h4oe__d1gsda2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1h4og__d2trxb___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1h4oh__d3d21b___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cell [GO:0005623]; cytoplasm [GO:0005737]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]	protein disulfide oxidoreductase activity [GO:0015035]
d1h4pa__d3ai0a___1	Fungi	Metazoa	Ascomycota	Arthropoda	extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; fungal-type vacuole [GO:0000324]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; fungal-type vacuole [GO:0000324]		glucan exo-1,3-beta-glucosidase activity [GO:0004338]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1h4pb__d4m81a___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; fungal-type vacuole [GO:0000324]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]; cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]	cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; fungal-type vacuole [GO:0000324]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]	glucan exo-1,3-beta-glucosidase activity [GO:0004338]	cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]
d1h4qb1_d2g4cb1__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	prolyl-tRNA aminoacylation [GO:0006433]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1h4sb1_d1g5ib1__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; respiratory electron transport chain [GO:0022904]	prolyl-tRNA aminoacylation [GO:0006433]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; respiratory electron transport chain [GO:0022904]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1h4td1_d1adjb1__1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	prolyl-tRNA aminoacylation [GO:0006433]	histidyl-tRNA aminoacylation [GO:0006427]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]
d1h4yb__d1th8b___1			Firmicutes	Firmicutes	anti-sigma factor antagonist activity [GO:0043856]; antisigma factor binding [GO:0045152]; sporulation resulting in formation of a cellular spore [GO:0030435]	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; sigma factor antagonist activity [GO:0016989]; asexual sporulation [GO:0030436]; negative regulation of sporulation resulting in formation of a cellular spore [GO:0042174]; negative regulation of transcription, DNA-templated [GO:0045892]; sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]	asexual sporulation [GO:0030436]; negative regulation of sporulation resulting in formation of a cellular spore [GO:0042174]; negative regulation of transcription, DNA-templated [GO:0045892]; sporulation resulting in formation of a cellular spore [GO:0030435]			anti-sigma factor antagonist activity [GO:0043856]; antisigma factor binding [GO:0045152]	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; sigma factor antagonist activity [GO:0016989]
d1h52a__d4rtea___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	extracellular region [GO:0005576]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1h54a1_d3a3va___1			Firmicutes	Firmicutes	carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; carbohydrate metabolic process [GO:0005975]	oligosaccharide reducing-end xylanase activity [GO:0033951]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]			carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]	oligosaccharide reducing-end xylanase activity [GO:0033951]
d1h54b2_d1v7wa2__1			Firmicutes	Proteobacteria	carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; transferase activity [GO:0016740]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d1h55a__d1ck6a___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]	extracellular region [GO:0005576]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1h5ba__d5mtla2__1												
d1h5bb__d4oz4b2__1												
d1h5bd__d2cjul___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1h5ga__d1myp.2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]; chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	extracellular region [GO:0005576]; vacuole [GO:0005773]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1h5ia__d3wnua2__1	Viridiplantae		Streptophyta	Cyanobacteria	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1h5ka__d5sx7b2__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1h5ma__d1zbza___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; vacuole [GO:0005773]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1h5qb__d3tscc___1	Fungi		Basidiomycota	Actinobacteria	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]				mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1h5qe__d1m75a2__1	Fungi	Metazoa	Basidiomycota	Chordata	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d1h5qg__d4m89b___1	Fungi		Basidiomycota	Proteobacteria	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	fatty acid biosynthetic process [GO:0006633]			mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d1h5qh__d5o30d___1	Fungi		Basidiomycota	Actinobacteria	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]		mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]				mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]	
d1h5ql__d1mg0b2__1	Fungi	Metazoa	Basidiomycota	Chordata	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1h5ra__d2bo4f___1			Proteobacteria	Bacteroidetes	cytosol [GO:0005829]; glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]; mannosylglycerate biosynthetic process [GO:0051479]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	mannosylglycerate biosynthetic process [GO:0051479]	cytosol [GO:0005829]		glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]
d1h5rd__d1o7qa___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	cytosol [GO:0005829]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d1h5td__d2apca___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	Golgi medial cisterna [GO:0005797]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity [GO:0003827]; manganese ion binding [GO:0030145]; protein N-acetylglucosaminyltransferase activity [GO:0016262]; mannose metabolic process [GO:0006013]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	mannose metabolic process [GO:0006013]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]	cytosol [GO:0005829]	Golgi medial cisterna [GO:0005797]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity [GO:0003827]; manganese ion binding [GO:0030145]; protein N-acetylglucosaminyltransferase activity [GO:0016262]
d1h5va__d5bcac2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1h61a__d2prma___1		Metazoa	Proteobacteria	Chordata	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]		cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]
d1h63a__d3l67a___1			Proteobacteria	Proteobacteria	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d1h641__d1lnxb___1			Euryarchaeota	Crenarchaeota								
d1h64a__d1i4kk___1			Euryarchaeota	Euryarchaeota								
d1h64c__d1vu2t___1			Euryarchaeota									
d1h64e__d5mknh___1			Euryarchaeota	Euryarchaeota								
d1h64g__d1n9sg___1		Fungi	Euryarchaeota	Ascomycota		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]
d1h64h__d4f774___1			Euryarchaeota									
d1h64l__d1i81g___1			Euryarchaeota	Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]		
d1h64p__d1mgqd___1			Euryarchaeota	Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]		
d1h66b__d1kboc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d1h67a1_d1aa2a___1	Metazoa	Metazoa	Chordata	Chordata	actin binding [GO:0003779]; calmodulin binding [GO:0005516]; actomyosin structure organization [GO:0031032]	axolemma [GO:0030673]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; nucleolus [GO:0005730]; postsynaptic density [GO:0014069]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390]	actomyosin structure organization [GO:0031032]	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390]		axolemma [GO:0030673]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; nucleolus [GO:0005730]; postsynaptic density [GO:0014069]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]	actin binding [GO:0003779]; calmodulin binding [GO:0005516]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]
d1h69c__d1c7fa___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1h69d__d4fx2a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1h6ja__d2xw3b___1			Proteobacteria		cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]		CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]		cytoplasm [GO:0005737]		3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]	
d1h6jb__d4ho6a___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	extracellular polysaccharide biosynthetic process [GO:0045226]	cytoplasm [GO:0005737]		3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1h6ka2_d3q0pa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]	mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]
d1h6kb1_d4p8qb4__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; cell-cell signaling [GO:0007267]; female pregnancy [GO:0007565]; negative regulation of cold-induced thermogenesis [GO:0120163]; peptide catabolic process [GO:0043171]; protein catabolic process [GO:0030163]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]; SMAD protein signal transduction [GO:0060395]	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; cell-cell signaling [GO:0007267]; female pregnancy [GO:0007565]; negative regulation of cold-induced thermogenesis [GO:0120163]; peptide catabolic process [GO:0043171]; protein catabolic process [GO:0030163]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]; SMAD protein signal transduction [GO:0060395]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]	cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]	mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]	aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270]
d1h6kc2_d1h2ua1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]	mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]	mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]
d1h6ma__d3gxrb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1h6ta1_d1o6sa1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	pathogenesis [GO:0009405]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	heparin binding [GO:0008201]; lipid binding [GO:0008289]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1h6ta2_d1o6va2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	cell wall [GO:0005618]; extracellular region [GO:0005576]; entry of bacterium into host cell [GO:0035635]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	entry of bacterium into host cell [GO:0035635]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; extracellular region [GO:0005576]	heparin binding [GO:0008201]; lipid binding [GO:0008289]	
d1h6ta2_d1s78a2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	pathogenesis [GO:0009405]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	heparin binding [GO:0008201]; lipid binding [GO:0008289]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]
d1h6ua2_d2wqxa1__1			Firmicutes	Firmicutes	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		heparin binding [GO:0008201]; lipid binding [GO:0008289]
d1h6ve3_d1v59a3__1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; mercury ion binding [GO:0045340]; NAD(P)H oxidase activity [GO:0016174]; protein homodimerization activity [GO:0042803]; selenate reductase activity [GO:0033797]; thioredoxin-disulfide reductase activity [GO:0004791]; benzene-containing compound metabolic process [GO:0042537]; cell redox homeostasis [GO:0045454]; cellular response to copper ion [GO:0071280]; cellular response to hyperoxia [GO:0071455]; halogen metabolic process [GO:0070276]; hydrogen peroxide catabolic process [GO:0042744]; NADPH oxidation [GO:0070995]; placenta development [GO:0001890]; positive regulation of cell death [GO:0010942]; protein tetramerization [GO:0051262]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to hyperoxia [GO:0055093]; response to oxidative stress [GO:0006979]; response to selenium ion [GO:0010269]; selenocysteine metabolic process [GO:0016259]	cell [GO:0005623]; glycine cleavage complex [GO:0005960]; mitochondrial nucleoid [GO:0042645]; mitochondrial oxoglutarate dehydrogenase complex [GO:0009353]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glycine dehydrogenase (decarboxylating) activity [GO:0004375]; oxoglutarate dehydrogenase (succinyl-transferring) activity [GO:0004591]; pyruvate dehydrogenase activity [GO:0004738]; 2-oxoglutarate metabolic process [GO:0006103]; cell redox homeostasis [GO:0045454]; glycine catabolic process [GO:0006546]; hydrogen peroxide metabolic process [GO:0042743]; isoleucine catabolic process [GO:0006550]; L-serine biosynthetic process [GO:0006564]; leucine catabolic process [GO:0006552]; pyruvate metabolic process [GO:0006090]; valine catabolic process [GO:0006574]	benzene-containing compound metabolic process [GO:0042537]; cell redox homeostasis [GO:0045454]; cellular response to copper ion [GO:0071280]; cellular response to hyperoxia [GO:0071455]; halogen metabolic process [GO:0070276]; hydrogen peroxide catabolic process [GO:0042744]; NADPH oxidation [GO:0070995]; placenta development [GO:0001890]; positive regulation of cell death [GO:0010942]; protein tetramerization [GO:0051262]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to hyperoxia [GO:0055093]; response to oxidative stress [GO:0006979]; response to selenium ion [GO:0010269]; selenocysteine metabolic process [GO:0016259]	2-oxoglutarate metabolic process [GO:0006103]; cell redox homeostasis [GO:0045454]; glycine catabolic process [GO:0006546]; hydrogen peroxide metabolic process [GO:0042743]; isoleucine catabolic process [GO:0006550]; leucine catabolic process [GO:0006552]; L-serine biosynthetic process [GO:0006564]; pyruvate metabolic process [GO:0006090]; valine catabolic process [GO:0006574]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]	cell [GO:0005623]; glycine cleavage complex [GO:0005960]; mitochondrial nucleoid [GO:0042645]; mitochondrial oxoglutarate dehydrogenase complex [GO:0009353]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; mercury ion binding [GO:0045340]; NAD(P)H oxidase activity [GO:0016174]; protein homodimerization activity [GO:0042803]; selenate reductase activity [GO:0033797]; thioredoxin-disulfide reductase activity [GO:0004791]	dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glycine dehydrogenase (decarboxylating) activity [GO:0004375]; oxoglutarate dehydrogenase (succinyl-transferring) activity [GO:0004591]; pyruvate dehydrogenase activity [GO:0004738]
d1h6xa1_d1of4a___1			Firmicutes	Thermotogae	cellulosome [GO:0043263]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	cellulosome [GO:0043263]		endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1h6ya__d4jklb1__1			Firmicutes	Firmicutes	cellulosome [GO:0043263]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	cellulosome [GO:0043263]		endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1h6za5_d1kc7a2__1				Firmicutes		ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]		pyruvate metabolic process [GO:0006090]				ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]
d1h72c1_d3p3ca1__1			Euryarchaeota	Aquificae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	threonine biosynthetic process [GO:0009088]	lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d1h74a2_d3d4jb2__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]	cytosol [GO:0005829]; ATP binding [GO:0005524]; diphosphomevalonate decarboxylase activity [GO:0004163]; Hsp70 protein binding [GO:0030544]; protein homodimerization activity [GO:0042803]; cholesterol biosynthetic process [GO:0006695]; dolichyl diphosphate biosynthetic process [GO:0006489]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; positive regulation of cell population proliferation [GO:0008284]; regulation of cholesterol biosynthetic process [GO:0045540]	threonine biosynthetic process [GO:0009088]	cholesterol biosynthetic process [GO:0006695]; dolichyl diphosphate biosynthetic process [GO:0006489]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; positive regulation of cell population proliferation [GO:0008284]; regulation of cholesterol biosynthetic process [GO:0045540]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]	ATP binding [GO:0005524]; diphosphomevalonate decarboxylase activity [GO:0004163]; Hsp70 protein binding [GO:0030544]; protein homodimerization activity [GO:0042803]
d1h74b1_d2qbde1__1			Euryarchaeota		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]		threonine biosynthetic process [GO:0009088]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]	
d1h74d1_d1ktvb3__1			Euryarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]	threonine biosynthetic process [GO:0009088]	translational elongation [GO:0006414]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]	GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]
d1h76a1_d2hava1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular space [GO:0005615]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; cellular iron ion homeostasis [GO:0006879]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cellular iron ion homeostasis [GO:0006879]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cell [GO:0005623]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d1h76a2_d4h0wa2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular space [GO:0005615]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; cellular iron ion homeostasis [GO:0006879]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cellular iron ion homeostasis [GO:0006879]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cell [GO:0005623]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d1h77a__d5r1rc2__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1h7fa__d4g3pa1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]; adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]
d1h7oa__d5f4xb___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	I band [GO:0031674]; M band [GO:0031430]	porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]	fructose-bisphosphate aldolase activity [GO:0004332]
d1h7wa2_d2j6xb___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d1h7wa5_d2gmha3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	integral component of mitochondrial inner membrane [GO:0031305]; membrane [GO:0016020]; mitochondrion [GO:0005739]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; electron-transferring-flavoprotein dehydrogenase activity [GO:0004174]; flavin adenine dinucleotide binding [GO:0050660]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, oxidizing metal ions with flavin as acceptor [GO:0043783]; ubiquinone binding [GO:0048039]; electron transport chain [GO:0022900]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	electron transport chain [GO:0022900]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	integral component of mitochondrial inner membrane [GO:0031305]; membrane [GO:0016020]; mitochondrion [GO:0005739]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; electron-transferring-flavoprotein dehydrogenase activity [GO:0004174]; flavin adenine dinucleotide binding [GO:0050660]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, oxidizing metal ions with flavin as acceptor [GO:0043783]; ubiquinone binding [GO:0048039]
d1h7wc3_d1e6ea1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]
d1h7wd1_d1qlab4__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]		beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	
d1h7xa1_d2b76n1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1h7xc1_d5c2tf2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d1h7xc5_d2uzab5__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	electron transport chain [GO:0022900]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d1h7zc__d3u6xl2__1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]		
d1h81b2_d2ignh2__1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]		apoplast [GO:0048046]; plant-type cell wall [GO:0009505]		flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]
d1h81b2_d2xafa3__1	Viridiplantae	Metazoa	Streptophyta	Chordata	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1h81c2_d1cc2a2__1	Viridiplantae		Streptophyta	Actinobacteria	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	cholesterol metabolic process [GO:0008203]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	extracellular region [GO:0005576]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]
d1h82a2_d1iuva2__1	Viridiplantae		Streptophyta	Proteobacteria	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	benzoate catabolic process via hydroxylation [GO:0043640]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]		flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1h82a2_d4uxna3__1	Viridiplantae	Metazoa	Streptophyta	Chordata	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1h82c2_d1kifb2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d1h83b2_d1bgna2__1	Viridiplantae		Streptophyta	Proteobacteria	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	benzoate catabolic process via hydroxylation [GO:0043640]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]		flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1h86c2_d1gnda2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; midbody [GO:0030496]; GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]; negative regulation of axonogenesis [GO:0050771]; negative regulation of protein targeting to membrane [GO:0090315]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	negative regulation of axonogenesis [GO:0050771]; negative regulation of protein targeting to membrane [GO:0090315]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; midbody [GO:0030496]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]	GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]
d1h8ea2_d2jj2c1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1h8eb2_d5knde1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1h8ed1_d3j9te4__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	ATP synthesis coupled proton transport [GO:0015986]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]
d1h8ef1_d2qe7c3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1h8ef2_d2jizc1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1h8hb2_d4yxwd1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1h8he3_d3ziap2__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1h8hf1_d1e79b1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1h8hf1_d5kncd3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1h8hf2_d2qe7e1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1h8la1_d5k39b1__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; metallocarboxypeptidase activity [GO:0004181]; serine-type carboxypeptidase activity [GO:0004185]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	cell wall [GO:0005618]; extracellular region [GO:0005576]; S-layer [GO:0030115]; carbohydrate binding [GO:0030246]; polysaccharide catabolic process [GO:0000272]	proteolysis [GO:0006508]	polysaccharide catabolic process [GO:0000272]	integral component of membrane [GO:0016021]	cell wall [GO:0005618]; extracellular region [GO:0005576]; S-layer [GO:0030115]	metallocarboxypeptidase activity [GO:0004181]; serine-type carboxypeptidase activity [GO:0004185]; zinc ion binding [GO:0008270]	carbohydrate binding [GO:0030246]
d1h8oa1_d5gs1r___1												
d1h8ob1_d1kj2l___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1h8ob2_d5t5nh1__1		Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]; chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]		detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]		basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]		chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1h8sb1_d1j1ph___1		Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1h8ub__d3p7fc1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; transport vesicle [GO:0030133]; carbohydrate binding [GO:0030246]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; heparin binding [GO:0008201]; defense response to bacterium [GO:0042742]; neutrophil degranulation [GO:0043312]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	defense response to bacterium [GO:0042742]; neutrophil degranulation [GO:0043312]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; transport vesicle [GO:0030133]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; heparin binding [GO:0008201]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1h8va__d1hkd.2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	polysaccharide catabolic process [GO:0000272]				cellulase activity [GO:0008810]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1h8vc__d4d5ia___1	Fungi	Fungi	Ascomycota	Ascomycota	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	cellulase activity [GO:0008810]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d1h8vd__d5hxve___1	Fungi	Fungi	Ascomycota	Ascomycota	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]			cellulase activity [GO:0008810]	endo-1,4-beta-xylanase activity [GO:0031176]
d1h8vf__d2bvva___1	Fungi		Ascomycota	Firmicutes	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]			cellulase activity [GO:0008810]	endo-1,4-beta-xylanase activity [GO:0031176]
d1h8vf__d5gltb1__1	Fungi	Metazoa	Ascomycota	Nematoda (roundworms)	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]	polysaccharide catabolic process [GO:0000272]				cellulase activity [GO:0008810]	carbohydrate binding [GO:0030246]
d1h8xa__d1hi5a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; chemotaxis [GO:0006935]; defense response to virus [GO:0051607]; neutrophil degranulation [GO:0043312]; RNA catabolic process [GO:0006401]; RNA phosphodiester bond hydrolysis [GO:0090501]	RNA phosphodiester bond hydrolysis [GO:0090501]	chemotaxis [GO:0006935]; defense response to virus [GO:0051607]; neutrophil degranulation [GO:0043312]; RNA catabolic process [GO:0006401]; RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular exosome [GO:0070062]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1h8xb__d1rbxa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	RNA phosphodiester bond hydrolysis [GO:0090501]		extracellular exosome [GO:0070062]	extracellular region [GO:0005576]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1h97b__d1ux8a___1	Metazoa		Platyhelminthes	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell [GO:0005623]; cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; thioredoxin peroxidase activity [GO:0008379]
d1h9ja1_d1h9ra1__1			Proteobacteria	Proteobacteria	molybdate ion transport [GO:0015689]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]; molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]		cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]
d1h9ma1_d1b9na4__1			Proteobacteria	Proteobacteria	molybdate ion transport [GO:0015689]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]; molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]		cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]
d1h9ma1_d1oxtb1__1			Proteobacteria	Crenarchaeota	molybdate ion transport [GO:0015689]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; carbohydrate transport [GO:0008643]	molybdate ion transport [GO:0015689]	carbohydrate transport [GO:0008643]		ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]
d1h9mb2_d1guta___1			Proteobacteria	Firmicutes	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]				
d1h9oa__d1hctb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]; 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; insulin binding [GO:0043559]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; insulin-like growth factor receptor binding [GO:0005159]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; axon guidance [GO:0007411]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	axon guidance [GO:0007411]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; platelet activation [GO:0030168]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; insulin binding [GO:0043559]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]
d1h9oa__d3vrqb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]; 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; insulin binding [GO:0043559]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; insulin-like growth factor receptor binding [GO:0005159]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; axon guidance [GO:0007411]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	membrane raft [GO:0045121]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]; cell surface receptor signaling pathway [GO:0007166]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of MAP kinase activity [GO:0043407]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	axon guidance [GO:0007411]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; platelet activation [GO:0030168]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cell surface receptor signaling pathway [GO:0007166]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of MAP kinase activity [GO:0043407]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]	membrane raft [GO:0045121]; plasma membrane [GO:0005886]	1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; insulin binding [GO:0043559]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]	calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]
d1h9ra1_d1gute___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]; molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]	
d1h9ra2_d2awob1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]; molybdate ion transport [GO:0015689]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]; activating transcription factor binding [GO:0033613]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	molybdate ion transport [GO:0015689]	maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cytosol [GO:0005829]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]	activating transcription factor binding [GO:0033613]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; ATP binding [GO:0005524]
d1h9rb2_d1gusb___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]; molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]	
d1h9ta1_d2dk5a1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; fatty-acyl-CoA binding [GO:0000062]; fatty acid oxidation [GO:0019395]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fatty acid metabolic process [GO:0019217]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; RNA polymerase III complex [GO:0005666]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; double-stranded DNA binding [GO:0003690]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of type I interferon production [GO:0032481]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase III [GO:0006383]	fatty acid oxidation [GO:0019395]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fatty acid metabolic process [GO:0019217]	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of type I interferon production [GO:0032481]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase III [GO:0006383]	cytosol [GO:0005829]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; RNA polymerase III complex [GO:0005666]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; fatty-acyl-CoA binding [GO:0000062]	DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; double-stranded DNA binding [GO:0003690]
d1h9va1_d4yhil2__1	Metazoa		Chordata		Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]		Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]		Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]		IgG binding [GO:0019864]	
d1h9xa1_d1qn2c___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1h9xb1_d1e2rb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1h9xb1_d2c1va2__1			Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	
d1h9ya1_d1vyda___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]	periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1ha0a1_d4kdoa1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d1ha1a1_d2cq3a1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; dendrite morphogenesis [GO:0048813]; fibroblast growth factor receptor signaling pathway [GO:0008543]; intracellular estrogen receptor signaling pathway [GO:0030520]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; neuromuscular process controlling balance [GO:0050885]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell population proliferation [GO:0042127]; regulation of definitive erythrocyte differentiation [GO:0010724]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	dendrite morphogenesis [GO:0048813]; fibroblast growth factor receptor signaling pathway [GO:0008543]; intracellular estrogen receptor signaling pathway [GO:0030520]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; neuromuscular process controlling balance [GO:0050885]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell population proliferation [GO:0042127]; regulation of definitive erythrocyte differentiation [GO:0010724]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]
d1ha2a1_d1n5ua3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1ha2a1_d5dqfa3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1ha2a2_d5oria1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1ha2a3_d4lb2a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1ha2a3_d5otbb3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1ha3a1_d4j0qa2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1ha3a2_d3agjg6__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	
d1ha3b2_d4j0qa3__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1ha4a__d3i9ha___1	Metazoa		Chordata	Firmicutes	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1ha4b__d3so1g___1	Metazoa		Chordata	Firmicutes	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1ha5b1_d1ltif___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]		killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ha5b2_d1ts3b2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ha5d2_d2rdga2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1ha7a__d1ngkg___1			Cyanobacteria	Actinobacteria	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	phycobilisome [GO:0030089]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1ha7e__d2uumk___1			Cyanobacteria	Cyanobacteria	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	phycobilisome [GO:0030089]	phycobilisome [GO:0030089]		
d1ha7k__d1jw8a___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1hage__d1hava___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1hah.1_d1utka___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1hao.1_d1w3c.2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hap.1_d2asub___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; receptor tyrosine kinase binding [GO:0030971]; serine-type endopeptidase activity [GO:0004252]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of macrophage chemotaxis [GO:0010758]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of macrophage chemotaxis [GO:0010758]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	receptor tyrosine kinase binding [GO:0030971]; serine-type endopeptidase activity [GO:0004252]
d1haua1_d2ppcc1__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1haua2_d2h3xc___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; amine dehydrogenase activity [GO:0030058]; aralkylamine dehydrogenase (azurin) activity [GO:0030059]	nitrogen compound metabolic process [GO:0006807]			periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	amine dehydrogenase activity [GO:0030058]; aralkylamine dehydrogenase (azurin) activity [GO:0030059]
d1hawa1_d3sbre2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	nitrogen compound metabolic process [GO:0006807]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]		membrane [GO:0016020]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d1hawa2_d5azub___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1haxb__d1ekbb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; scavenger receptor activity [GO:0005044]; serine-type endopeptidase activity [GO:0004252]; protein digestion [GO:0044256]; trypsinogen activation [GO:0032023]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	protein digestion [GO:0044256]; trypsinogen activation [GO:0032023]	extracellular space [GO:0005615]	integral component of membrane [GO:0016021]; membrane [GO:0016020]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	scavenger receptor activity [GO:0005044]; serine-type endopeptidase activity [GO:0004252]
d1hayb__d1hxe.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d1hb4a__d5pjga___1	Fungi	Metazoa	Ascomycota	Chordata	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]; penicillin biosynthetic process [GO:0042318]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	penicillin biosynthetic process [GO:0042318]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]		blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d1hb6a__d2wh5d___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]			endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]		fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]
d1hb8b__d1hbka___1	Metazoa		Chordata	Apicomplexa	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]			endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]		fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]
d1hb8b__d3flvb1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]; autophagy of peroxisome [GO:0030242]; fatty acid catabolic process [GO:0009062]		autophagy of peroxisome [GO:0030242]; fatty acid catabolic process [GO:0009062]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]
d1hb8c__d3fp5a___1	Metazoa	Fungi	Chordata	Basidiomycota	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; metal ion binding [GO:0046872]			endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]		fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; metal ion binding [GO:0046872]
d1hbaa__d5b13d___1	Metazoa		Chordata	Rhodophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1hbab__d3pi4a___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1hbba__d1jy7d___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1hbga__d2blia___1	Metazoa	Metazoa	Annelida	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1hbha__d1gh0g___1	Metazoa		Chordata	Cyanobacteria	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1hbhc__d4xdia___1	Metazoa	Viridiplantae	Chordata	Chlorophyta	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	hemoglobin complex [GO:0005833]	cell [GO:0005623]; cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; thioredoxin peroxidase activity [GO:0008379]
d1hbia__d3g46b___1	Metazoa	Metazoa	Mollusca	Mollusca	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1hbka__d2wh5e___1		Metazoa	Apicomplexa	Chordata	fatty-acyl-CoA binding [GO:0000062]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]					fatty-acyl-CoA binding [GO:0000062]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]
d1hbme1_d5a8ke2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]; methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	cytoplasm [GO:0005737]		coenzyme-B sulfoethylthiotransferase activity [GO:0050524]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]
d1hbnb1_d5n1qb2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	cytoplasm [GO:0005737]		coenzyme-B sulfoethylthiotransferase activity [GO:0050524]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]
d1hbpa__d3q6la___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]		brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	extracellular space [GO:0005615]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1hbrb__d1s61b___1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cell [GO:0005623]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	heme binding [GO:0020037]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1hbrb__d3uh6a___1	Metazoa	Metazoa	Chordata	Mollusca	cell [GO:0005623]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cell [GO:0005623]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1hbrc__d2zlva___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cell [GO:0005623]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1hbrd__d5eqma___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]	cell [GO:0005623]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	heme binding [GO:0020037]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1hbsa__d5toui___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1hbse__d5x2rb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1hbt.1_d1hv7a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1hbuf__d5a8rc___1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	cytoplasm [GO:0005737]		coenzyme-B sulfoethylthiotransferase activity [GO:0050524]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]
d1hbxa__d1egwa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone deacetylase binding [GO:0042826]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; serum response element binding [GO:0010736]; transcription factor binding [GO:0008134]; actin cytoskeleton organization [GO:0030036]; angiogenesis involved in wound healing [GO:0060055]; associative learning [GO:0008306]; bicellular tight junction assembly [GO:0070830]; branching involved in blood vessel morphogenesis [GO:0001569]; bronchus cartilage development [GO:0060532]; cardiac myofibril assembly [GO:0055003]; cardiac vascular smooth muscle cell differentiation [GO:0060947]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-matrix adhesion [GO:0007160]; cellular response to glucose stimulus [GO:0071333]; cellular senescence [GO:0090398]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; epithelial cell-cell adhesion [GO:0090136]; epithelial structure maintenance [GO:0010669]; erythrocyte development [GO:0048821]; eyelid development in camera-type eye [GO:0061029]; face development [GO:0060324]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula formation [GO:0060347]; hematopoietic stem cell differentiation [GO:0060218]; hippocampus development [GO:0021766]; long-term memory [GO:0007616]; long-term synaptic depression [GO:0060292]; lung morphogenesis [GO:0060425]; lung smooth muscle development [GO:0061145]; megakaryocyte development [GO:0035855]; mesoderm formation [GO:0001707]; morphogenesis of an epithelial sheet [GO:0002011]; mRNA transcription by RNA polymerase II [GO:0042789]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; neuron development [GO:0048666]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; positive regulation of axon extension [GO:0045773]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of transcription by glucose [GO:0046016]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003257]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of transcription via serum response element binding [GO:0010735]; positive thymic T cell selection [GO:0045059]; primitive streak formation [GO:0090009]; regulation of cell adhesion [GO:0030155]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of water loss via skin [GO:0033561]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to toxic substance [GO:0009636]; sarcomere organization [GO:0045214]; skin morphogenesis [GO:0043589]; stress fiber assembly [GO:0043149]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea cartilage development [GO:0060534]; transcription by RNA polymerase II [GO:0006366]; trophectodermal cell differentiation [GO:0001829]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	actin cytoskeleton organization [GO:0030036]; angiogenesis involved in wound healing [GO:0060055]; associative learning [GO:0008306]; bicellular tight junction assembly [GO:0070830]; branching involved in blood vessel morphogenesis [GO:0001569]; bronchus cartilage development [GO:0060532]; cardiac myofibril assembly [GO:0055003]; cardiac vascular smooth muscle cell differentiation [GO:0060947]; cell-matrix adhesion [GO:0007160]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to glucose stimulus [GO:0071333]; cellular senescence [GO:0090398]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; epithelial cell-cell adhesion [GO:0090136]; epithelial structure maintenance [GO:0010669]; erythrocyte development [GO:0048821]; eyelid development in camera-type eye [GO:0061029]; face development [GO:0060324]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula formation [GO:0060347]; hematopoietic stem cell differentiation [GO:0060218]; hippocampus development [GO:0021766]; long-term memory [GO:0007616]; long-term synaptic depression [GO:0060292]; lung morphogenesis [GO:0060425]; lung smooth muscle development [GO:0061145]; megakaryocyte development [GO:0035855]; mesoderm formation [GO:0001707]; morphogenesis of an epithelial sheet [GO:0002011]; mRNA transcription by RNA polymerase II [GO:0042789]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; neuron development [GO:0048666]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; positive regulation of axon extension [GO:0045773]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of transcription by glucose [GO:0046016]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003257]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of transcription via serum response element binding [GO:0010735]; positive thymic T cell selection [GO:0045059]; primitive streak formation [GO:0090009]; regulation of cell adhesion [GO:0030155]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of water loss via skin [GO:0033561]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to toxic substance [GO:0009636]; sarcomere organization [GO:0045214]; skin morphogenesis [GO:0043589]; stress fiber assembly [GO:0043149]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea cartilage development [GO:0060534]; transcription by RNA polymerase II [GO:0006366]; trophectodermal cell differentiation [GO:0001829]	apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	cell [GO:0005623]; cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone deacetylase binding [GO:0042826]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; serum response element binding [GO:0010736]; transcription factor binding [GO:0008134]	activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1hc7b1_d4hwob2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	prolyl-tRNA aminoacylation [GO:0006433]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1hc7d1_d4ttva2__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	prolyl-tRNA aminoacylation [GO:0006433]	threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]
d1hcha__d2x08a___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; vacuole [GO:0005773]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1hcia4_d1hcia1__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; pseudopodium [GO:0031143]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]; actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; pseudopodium [GO:0031143]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]; actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; pseudopodium [GO:0031143]; Z disc [GO:0030018]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; pseudopodium [GO:0031143]; Z disc [GO:0030018]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]
d1hcib2_d1owaa___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; pseudopodium [GO:0031143]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]; actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin cytoskeleton [GO:0015629]; axon [GO:0030424]; cuticular plate [GO:0032437]; cytosol [GO:0005829]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; actin filament capping [GO:0051693]; actin filament organization [GO:0007015]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; hemopoiesis [GO:0030097]; lymphocyte homeostasis [GO:0002260]; MAPK cascade [GO:0000165]; plasma membrane organization [GO:0007009]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of protein binding [GO:0032092]; positive regulation of T cell proliferation [GO:0042102]; regulation of cell shape [GO:0008360]	actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin filament capping [GO:0051693]; actin filament organization [GO:0007015]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; hemopoiesis [GO:0030097]; lymphocyte homeostasis [GO:0002260]; MAPK cascade [GO:0000165]; plasma membrane organization [GO:0007009]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of protein binding [GO:0032092]; positive regulation of T cell proliferation [GO:0042102]; regulation of cell shape [GO:0008360]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; pseudopodium [GO:0031143]; Z disc [GO:0030018]	actin cytoskeleton [GO:0015629]; axon [GO:0030424]; cuticular plate [GO:0032437]; cytosol [GO:0005829]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1hcib3_d5j4oa2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; pseudopodium [GO:0031143]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]; actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin cytoskeleton [GO:0015629]; axon [GO:0030424]; cuticular plate [GO:0032437]; cytosol [GO:0005829]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; actin filament capping [GO:0051693]; actin filament organization [GO:0007015]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; hemopoiesis [GO:0030097]; lymphocyte homeostasis [GO:0002260]; MAPK cascade [GO:0000165]; plasma membrane organization [GO:0007009]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of protein binding [GO:0032092]; positive regulation of T cell proliferation [GO:0042102]; regulation of cell shape [GO:0008360]	actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin filament capping [GO:0051693]; actin filament organization [GO:0007015]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; hemopoiesis [GO:0030097]; lymphocyte homeostasis [GO:0002260]; MAPK cascade [GO:0000165]; plasma membrane organization [GO:0007009]; porphyrin-containing compound biosynthetic process [GO:0006779]; positive regulation of protein binding [GO:0032092]; positive regulation of T cell proliferation [GO:0042102]; regulation of cell shape [GO:0008360]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; pseudopodium [GO:0031143]; Z disc [GO:0030018]	actin cytoskeleton [GO:0015629]; axon [GO:0030424]; cuticular plate [GO:0032437]; cytosol [GO:0005829]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1hcma1_d1aofa1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1hcmb1_d1hzua1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1hcva__d2bsva4__1												
d1hcye2_d5i38b___1	Metazoa		Arthropoda	Firmicutes	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; oxygen carrier activity [GO:0005344]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]			extracellular space [GO:0005615]		metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; oxygen carrier activity [GO:0005344]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d1hdaa__d1mdnb___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1hdad__d4esaa___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1hdbd__d2uump___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1hdea__d2oleb2__1		Metazoa	Proteobacteria	Chordata	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	haloalkane dehalogenase activity [GO:0018786]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1hdia__d2y3ia___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; phosphorylation [GO:0016310]; positive regulation of oxidative phosphorylation [GO:1903862]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; membrane raft [GO:0045121]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; protein-disulfide reductase activity [GO:0047134]; canonical glycolysis [GO:0061621]; cellular response to hypoxia [GO:0071456]; epithelial cell differentiation [GO:0030855]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of angiogenesis [GO:0016525]; phosphorylation [GO:0016310]; plasminogen activation [GO:0031639]; positive regulation of oxidative phosphorylation [GO:1903862]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; phosphorylation [GO:0016310]; positive regulation of oxidative phosphorylation [GO:1903862]	canonical glycolysis [GO:0061621]; cellular response to hypoxia [GO:0071456]; epithelial cell differentiation [GO:0030855]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of angiogenesis [GO:0016525]; phosphorylation [GO:0016310]; plasminogen activation [GO:0031639]; positive regulation of oxidative phosphorylation [GO:1903862]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; membrane raft [GO:0045121]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; protein-disulfide reductase activity [GO:0047134]
d1hdja__d2dn9a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; sperm head [GO:0061827]; ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; protein folding chaperone [GO:0044183]; transcription corepressor activity [GO:0003714]; unfolded protein binding [GO:0051082]; chaperone cofactor-dependent protein refolding [GO:0051085]; forebrain development [GO:0030900]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; positive regulation of ATPase activity [GO:0032781]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; postsynaptic membrane [GO:0045211]; ATP binding [GO:0005524]; GTPase regulator activity [GO:0030695]; Hsp70 protein binding [GO:0030544]; IkappaB kinase complex binding [GO:0106137]; interferon-gamma receptor binding [GO:0005133]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; transcription factor binding [GO:0008134]; unfolded protein binding [GO:0051082]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation-induced cell death of T cells [GO:0006924]; cell aging [GO:0007569]; mitochondrial DNA replication [GO:0006264]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular junction development [GO:0007528]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell proliferation [GO:0042102]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to interferon-gamma [GO:0034341]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; small GTPase mediated signal transduction [GO:0007264]; T cell differentiation in thymus [GO:0033077]	chaperone cofactor-dependent protein refolding [GO:0051085]; forebrain development [GO:0030900]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; positive regulation of ATPase activity [GO:0032781]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]	activation-induced cell death of T cells [GO:0006924]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cell aging [GO:0007569]; mitochondrial DNA replication [GO:0006264]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular junction development [GO:0007528]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell proliferation [GO:0042102]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to interferon-gamma [GO:0034341]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; small GTPase mediated signal transduction [GO:0007264]; T cell differentiation in thymus [GO:0033077]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; sperm head [GO:0061827]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; postsynaptic membrane [GO:0045211]	ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; protein folding chaperone [GO:0044183]; transcription corepressor activity [GO:0003714]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; GTPase regulator activity [GO:0030695]; Hsp70 protein binding [GO:0030544]; IkappaB kinase complex binding [GO:0106137]; interferon-gamma receptor binding [GO:0005133]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; transcription factor binding [GO:0008134]; unfolded protein binding [GO:0051082]
d1hdka__d2nn8a___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; carbohydrate binding [GO:0030246]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; identical protein binding [GO:0042802]; multicellular organism development [GO:0007275]; regulation of activated T cell proliferation [GO:0046006]; regulation of T cell anergy [GO:0002667]; regulation of T cell cytokine production [GO:0002724]; T cell apoptotic process [GO:0070231]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	multicellular organism development [GO:0007275]; regulation of activated T cell proliferation [GO:0046006]; regulation of T cell anergy [GO:0002667]; regulation of T cell cytokine production [GO:0002724]; T cell apoptotic process [GO:0070231]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	carbohydrate binding [GO:0030246]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; identical protein binding [GO:0042802]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d1hdya2_d1n9ga2__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	mitochondrion [GO:0005739]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]
d1he1c1_d4i1og1__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; GTPase activator activity [GO:0005096]; pathogenesis [GO:0009405]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471]; phagophore assembly site membrane [GO:0034045]; transport vesicle [GO:0030133]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; autophagosome assembly [GO:0000045]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; positive regulation of glycoprotein metabolic process [GO:1903020]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; regulation of autophagosome assembly [GO:2000785]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; virion assembly [GO:0019068]	pathogenesis [GO:0009405]	autophagosome assembly [GO:0000045]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; positive regulation of glycoprotein metabolic process [GO:1903020]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; regulation of autophagosome assembly [GO:2000785]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; virion assembly [GO:0019068]	extracellular region [GO:0005576]	cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471]; phagophore assembly site membrane [GO:0034045]; transport vesicle [GO:0030133]	GTPase activator activity [GO:0005096]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1he7a1_d1agbb___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome membrane [GO:0055038]; ATP binding [GO:0005524]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; nerve growth factor binding [GO:0048406]; nerve growth factor receptor activity [GO:0010465]; neurotrophin binding [GO:0043121]; neurotrophin p75 receptor binding [GO:0005166]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of MAPKK activity [GO:0000186]; aging [GO:0007568]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; B cell differentiation [GO:0030183]; behavioral response to formalin induced pain [GO:0061368]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to nicotine [GO:0071316]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; learning or memory [GO:0007611]; mechanoreceptor differentiation [GO:0042490]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; neurotrophin TRK receptor signaling pathway [GO:0048011]; olfactory nerve development [GO:0021553]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; programmed cell death involved in cell development [GO:0010623]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to hydrostatic pressure [GO:0051599]; response to nutrient levels [GO:0031667]; response to radiation [GO:0009314]; Sertoli cell development [GO:0060009]; sympathetic nervous system development [GO:0048485]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of MAPKK activity [GO:0000186]; aging [GO:0007568]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; B cell differentiation [GO:0030183]; behavioral response to formalin induced pain [GO:0061368]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to nicotine [GO:0071316]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; learning or memory [GO:0007611]; mechanoreceptor differentiation [GO:0042490]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; neurotrophin TRK receptor signaling pathway [GO:0048011]; olfactory nerve development [GO:0021553]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; programmed cell death involved in cell development [GO:0010623]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to hydrostatic pressure [GO:0051599]; response to nutrient levels [GO:0031667]; response to radiation [GO:0009314]; Sertoli cell development [GO:0060009]; sympathetic nervous system development [GO:0048485]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome membrane [GO:0055038]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	ATP binding [GO:0005524]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; nerve growth factor binding [GO:0048406]; nerve growth factor receptor activity [GO:0010465]; neurotrophin binding [GO:0043121]; neurotrophin p75 receptor binding [GO:0005166]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1heed__d3b3ca___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	proteolysis [GO:0006508]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]
d1heee__d1obra___1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	proteolysis [GO:0006508]		extracellular space [GO:0005615]		metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1hege__d1g35b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hege__d3fv3c___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1heia1_d5a0fa___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d1hejc__d1exga___1			Actinobacteria	Actinobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]; xylan catabolic process [GO:0045493]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]
d1hejc__d4jo5a___1			Actinobacteria		endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]	
d1hema__d5i5qa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1hena__d1uiga___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1hepa__d168ld___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1hera__d6lyta___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1heua2_d2v7pc1__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	L-lactate dehydrogenase activity [GO:0004459]
d1heub2_d1p44a___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d1hezc1_d1s7uh___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hf4a__d1l48a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1hf4b__d1l14a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1hf6a__d2bfge2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d1hf7a__d3vd3c3__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1hf8a1_d1yd8h2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]; 1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]; axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1hfaa1_d1hx8b1__1	Metazoa	Metazoa	Chordata	Arthropoda	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]; 1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]; axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	cell [GO:0005623]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; 1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SNARE binding [GO:0000149]; chemical synaptic transmission [GO:0007268]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endocytosis [GO:0006897]; neuron-neuron synaptic transmission [GO:0007270]; phototaxis [GO:0042331]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle transport [GO:0048489]; vesicle budding from membrane [GO:0006900]	axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	chemical synaptic transmission [GO:0007268]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endocytosis [GO:0006897]; neuron-neuron synaptic transmission [GO:0007270]; phototaxis [GO:0042331]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle transport [GO:0048489]; vesicle budding from membrane [GO:0006900]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]	cell [GO:0005623]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]	1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]	1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SNARE binding [GO:0000149]
d1hfbf__d4imcb___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]	N-acetylneuraminate lyase activity [GO:0008747]
d1hfoa__d3ce4b___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	extracellular space [GO:0005615]; cytokine activity [GO:0005125]; dopachrome isomerase activity [GO:0004167]; phenylpyruvate tautomerase activity [GO:0050178]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	extracellular space [GO:0005615]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cytokine activity [GO:0005125]; dopachrome isomerase activity [GO:0004167]; phenylpyruvate tautomerase activity [GO:0050178]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d1hfoc__d1ljtb___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	extracellular space [GO:0005615]; cytokine activity [GO:0005125]; dopachrome isomerase activity [GO:0004167]; phenylpyruvate tautomerase activity [GO:0050178]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	extracellular space [GO:0005615]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cytokine activity [GO:0005125]; dopachrome isomerase activity [GO:0004167]; phenylpyruvate tautomerase activity [GO:0050178]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d1hfpa__d1dr5a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d1hfqa__d3f91a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1hfqa__d4elbf1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1hfsa__d3keca1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1hfua1_d5n8ga1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1hfua3_d5d4hc2__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1hfxa__d1jkba___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; lactose biosynthetic process [GO:0005989]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	lactose biosynthetic process [GO:0005989]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1hfxa__d1l13a___1	Metazoa		Chordata		extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; lactose biosynthetic process [GO:0005989]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	lactose biosynthetic process [GO:0005989]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]	host cell cytoplasm [GO:0030430]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]	lysozyme activity [GO:0003796]
d1hfza__d3cb7b1__1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	lysozyme activity [GO:0003796]; metabolic process [GO:0008152]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	metabolic process [GO:0008152]	extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]	lysozyme activity [GO:0003796]
d1hg0b__d5k45b___1			Proteobacteria	Proteobacteria	asparaginase activity [GO:0004067]; asparagine metabolic process [GO:0006528]	cytoplasm [GO:0005737]; asparaginase activity [GO:0004067]; asparagine metabolic process [GO:0006528]	asparagine metabolic process [GO:0006528]	asparagine metabolic process [GO:0006528]		cytoplasm [GO:0005737]	asparaginase activity [GO:0004067]	asparaginase activity [GO:0004067]
d1hg3d__d1w0mc___1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1hg3d__d4jeqe___1			Euryarchaeota		cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1hg3e__d4bi5m___1			Euryarchaeota		cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	triose-phosphate isomerase activity [GO:0004807]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]
d1hg3f__d2wsqb___1			Euryarchaeota		cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1hg3h__d5i3ka___1			Euryarchaeota		cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1hg5a1_d1o3xa___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]; 1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]; axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]
d1hg7a1_d7msia___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]	extracellular region [GO:0005576]			extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1hg8a__d1idjb___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; pectin lyase activity [GO:0047490]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	pectin lyase activity [GO:0047490]
d1hgbc__d2oifc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d1hgcd__d2bv8m___1	Metazoa		Chordata	Rhodophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1hgda__d4qy1c___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1hgdc__d1kena___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1hgec__d4uo0a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1hgee__d4ktha1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1hgee__d5th1a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1hgfa__d5k9qq___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1hgfc__d5xl6b___1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d1hgfe__d1ru7k___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1hggc__d5vtza1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d1hgia__d5xl5b___1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d1hgie__d4nrkc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1hgja__d5vjka___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d1hgje__d5xl9a1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1hgya__d1qk0a___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]
d1hh2p1_d1ph3b___1			Thermotogae	Ciliophora	cytosol [GO:0005829]; DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]	telomere capping [GO:0016233]	cytosol [GO:0005829]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1hh6a1_d1ngxb2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1hh6a2_d3sgdl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1hh9a1_d3s35l1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell junction [GO:0030054]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; sorting endosome [GO:0097443]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; growth factor binding [GO:0019838]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; angiogenesis [GO:0001525]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic hemopoiesis [GO:0035162]; endothelial cell differentiation [GO:0045446]; endothelium development [GO:0003158]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of gene expression [GO:0010629]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vasculogenesis [GO:2001214]; protein autophosphorylation [GO:0046777]; protein kinase B signaling [GO:0043491]; regulation of cell shape [GO:0008360]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	angiogenesis [GO:0001525]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic hemopoiesis [GO:0035162]; endothelial cell differentiation [GO:0045446]; endothelium development [GO:0003158]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of gene expression [GO:0010629]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vasculogenesis [GO:2001214]; protein autophosphorylation [GO:0046777]; protein kinase B signaling [GO:0043491]; regulation of cell shape [GO:0008360]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; sorting endosome [GO:0097443]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; growth factor binding [GO:0019838]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d1hh9a2_d1ivlb___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1hh9b1_d1d6ea1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d1hhgb2_d1dqdh1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1hhge2_d2wahb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1hhha1_d2ny1b1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1hhha2_d3tvma1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1hhib2_d1r24a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1hhid1_d4pjfg1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hhie2_d3p9wb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]
d1hhjb2_d2dm3a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; podosome [GO:0002102]; ruffle [GO:0001726]; Z disc [GO:0030018]; actin binding [GO:0003779]; cell-cell adhesion mediator activity [GO:0098632]; muscle alpha-actinin binding [GO:0051371]; actin cytoskeleton organization [GO:0030036]; axon guidance [GO:0007411]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; dendrite self-avoidance [GO:0070593]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte development [GO:0003334]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin cytoskeleton organization [GO:0030036]; axon guidance [GO:0007411]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; dendrite self-avoidance [GO:0070593]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte development [GO:0003334]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; podosome [GO:0002102]; ruffle [GO:0001726]; Z disc [GO:0030018]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; cell-cell adhesion mediator activity [GO:0098632]; muscle alpha-actinin binding [GO:0051371]
d1hhjd1_d2dqjl___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1hhjd2_d1iaka2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]
d1hhjd2_d5ks9a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1hhje2_d2hp4a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]; antigen processing and presentation [GO:0019882]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; immune response [GO:0006955]; regulation of immune response [GO:0050776]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; immune response [GO:0006955]; regulation of immune response [GO:0050776]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]
d1hhka1_d2q86a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1hhka2_d1vgka2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hhkb2_d1fskf1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1hhkb2_d4orgb2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1hhkd1_d1oszb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1hhke2_d2ig2h1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1hhla__d215la___1	Metazoa		Chordata		extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1hhpa__d5p08a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hhqa__d1nued___1		Metazoa		Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]
d1hi6b2_d3d6gb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1hia.1_d1kxaa___1	Metazoa		Chordata		secretory granule [GO:0030141]; serine-type endopeptidase activity [GO:0004252]; regulation of systemic arterial blood pressure [GO:0003073]; zymogen activation [GO:0031638]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	regulation of systemic arterial blood pressure [GO:0003073]; zymogen activation [GO:0031638]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	secretory granule [GO:0030141]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	serine-type endopeptidase activity [GO:0004252]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]
d1hiha__d4y3ta___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hiia__d3pwrb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hika__d3wcyi___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]; activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; chloramphenicol O-acetyltransferase activity [GO:0008811]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; B cell activation involved in immune response [GO:0002312]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to dsRNA [GO:0071359]; cellular response to interferon-beta [GO:0035458]; cellular response to virus [GO:0098586]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; macrophage activation involved in immune response [GO:0002281]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	adaptive immune response [GO:0002250]; B cell activation involved in immune response [GO:0002312]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to dsRNA [GO:0071359]; cellular response to interferon-beta [GO:0035458]; cellular response to virus [GO:0098586]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; macrophage activation involved in immune response [GO:0002281]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]	chloramphenicol O-acetyltransferase activity [GO:0008811]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]
d1hila2_d2j8uf2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hila2_d4dvrh1__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1hilc1_d3dusc___1		Metazoa		Chordata								
d1himh1_d4pozc2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d1himh2_d5albl1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d1himj2_d2ql1a2__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	host cell surface receptor binding [GO:0046789]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1himj2_d3bp6a___1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	host cell surface receptor binding [GO:0046789]	
d1hinh1_d3upci___1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1hinh1_d4pjah2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hinh2_d5drxl1__1												
d1hinl1_d1wbza1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1hinl2_d2j1kx___1		Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1hioc__d3mvdc___1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleosome [GO:0000786]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1hiwq__d2jmga___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	virion [GO:0019012]; structural molecule activity [GO:0005198]; viral process [GO:0016032]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral process [GO:0016032]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	virion [GO:0019012]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	structural molecule activity [GO:0005198]
d1hiwq__d5kz9a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; reverse transcription [GO:0001171]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; reverse transcription [GO:0001171]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	viral nucleocapsid [GO:0019013]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d1hiwr__d2k4ha___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hixa__d3exua___1			Actinobacteria	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d1hixa__d4yw3b1__1			Actinobacteria	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1hixb__d1m4wa___1			Actinobacteria	Actinobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]
d1hixb__d5gm5f___1		Fungi	Actinobacteria	Ascomycota	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	cellulase activity [GO:0008810]
d1hiza__d3apgd1__1			Firmicutes	Euryarchaeota	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1hj4a2_d1hzua2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1hj4b1_d1qn2a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1hj8a__d4abba___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1hjbf__d3wtva___1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]
d1hjja__d2e8ba___1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]; bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; molybdenum cofactor guanylyltransferase activity [GO:0061603]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; molybdenum cofactor guanylyltransferase activity [GO:0061603]
d1hjma__d4hlsb___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d1hjoa1_d1glfz2__1	Metazoa		Chordata	Proteobacteria	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	cytosol [GO:0005829]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d1hjsd__d3zjkb___1	Fungi		Ascomycota	Deinococcus-Thermus	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]; cell wall macromolecule catabolic process [GO:0016998]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	cell wall macromolecule catabolic process [GO:0016998]	cellulose catabolic process [GO:0030245]			arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1hjua__d5fooa___1	Fungi		Ascomycota	Firmicutes	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]; cell wall macromolecule catabolic process [GO:0016998]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cell wall macromolecule catabolic process [GO:0016998]	carbohydrate metabolic process [GO:0005975]			arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1hjub__d5bwfb1__1	Fungi	Fungi	Ascomycota	Ascomycota	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]; cell wall macromolecule catabolic process [GO:0016998]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cell wall macromolecule catabolic process [GO:0016998]	carbohydrate metabolic process [GO:0005975]			arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1hjud__d5ofja1__1	Fungi		Ascomycota	Firmicutes	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]; cell wall macromolecule catabolic process [GO:0016998]	integral component of membrane [GO:0016021]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cell wall macromolecule catabolic process [GO:0016998]	cellulose catabolic process [GO:0030245]		integral component of membrane [GO:0016021]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d1hjza__d5hiha1__1			Euryarchaeota		ADP-ribosylglutamate hydrolase activity [GO:0140293]; peptidyl-glutamate ADP-deribosylation [GO:0140291]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	peptidyl-glutamate ADP-deribosylation [GO:0140291]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	ADP-ribosylglutamate hydrolase activity [GO:0140293]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1hk1a3_d4jk4b3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1hk4a1_d5orfd2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d1hk4a2_d4po0a2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; DNA binding [GO:0003677]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein oligomerization [GO:0032460]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein oligomerization [GO:0032460]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; DNA binding [GO:0003677]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]
d1hk5a1_d4zbqa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1hk5a2_d2bx8a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1hk5a2_d4bkea1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1hk9e__d4mmkl___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; bent DNA binding [GO:0003681]; RNA binding [GO:0003723]; negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]	cytosol [GO:0005829]	bent DNA binding [GO:0003681]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d1hkaa__d1cbka___1			Proteobacteria	Proteobacteria	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]			2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]
d1hkba2_d3djck1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	coenzyme A biosynthetic process [GO:0015937]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d1hkba3_d3h3oc2__1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d1hkba4_d3ub5a1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; calyx of Held [GO:0044305]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dense body [GO:0097433]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic actin cytoskeleton [GO:0098871]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; nitric-oxide synthase binding [GO:0050998]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973]; Tat protein binding [GO:0030957]; axonogenesis [GO:0007409]; cell motility [GO:0048870]; cellular response to cytochalasin B [GO:0072749]; negative regulation of protein binding [GO:0032091]; regulation of norepinephrine uptake [GO:0051621]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of transmembrane transporter activity [GO:0022898]; synaptic vesicle endocytosis [GO:0048488]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	axonogenesis [GO:0007409]; cell motility [GO:0048870]; cellular response to cytochalasin B [GO:0072749]; negative regulation of protein binding [GO:0032091]; regulation of norepinephrine uptake [GO:0051621]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of transmembrane transporter activity [GO:0022898]; synaptic vesicle endocytosis [GO:0048488]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; calyx of Held [GO:0044305]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dense body [GO:0097433]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic actin cytoskeleton [GO:0098871]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; nitric-oxide synthase binding [GO:0050998]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973]; Tat protein binding [GO:0030957]
d1hkbb2_d1qhab1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1hkbb4_d3cipa2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1hkca3_d3wxla2__1	Metazoa		Chordata		cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d1hkhb__d4i3fa1__1			Actinobacteria	Proteobacteria	peroxidase activity [GO:0004601]	hydrolase activity [GO:0016787]					peroxidase activity [GO:0004601]	hydrolase activity [GO:0016787]
d1hkll1_d5kg9l1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1hkll2_d2fjfi1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1hknb__d1ii4c___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1hknd__d4cjmc___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; growth factor activity [GO:0008083]; type 1 fibroblast growth factor receptor binding [GO:0005105]; type 2 fibroblast growth factor receptor binding [GO:0005111]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte development [GO:0002063]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor signaling pathway [GO:0008543]; intramembranous ossification [GO:0001957]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte development [GO:0002063]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor signaling pathway [GO:0008543]; intramembranous ossification [GO:0001957]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	growth factor activity [GO:0008083]; type 1 fibroblast growth factor receptor binding [GO:0005105]; type 2 fibroblast growth factor receptor binding [GO:0005111]
d1hknd__d4q91b1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1hknf__d4r6ub___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d1hksa__d5fd5e___1	Metazoa		Arthropoda	Proteobacteria	chromatin [GO:0000785]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; cellular response to heat [GO:0034605]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA binding [GO:0043388]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to heat stress [GO:0061408]; positive regulation of transcription, DNA-templated [GO:0045893]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]	cellular response to heat [GO:0034605]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA binding [GO:0043388]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to heat stress [GO:0061408]; response to heat [GO:0009408]		chromatin [GO:0000785]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]
d1hkxc__d5fw5a1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]; ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron migration [GO:2001222]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; ribonucleoprotein complex [GO:1990904]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of stress granule assembly [GO:0062029]; Ras protein signal transduction [GO:0007265]; stress granule assembly [GO:0034063]; type I interferon production [GO:0032606]; viral process [GO:0016032]	angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neuron migration [GO:2001222]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of stress granule assembly [GO:0062029]; Ras protein signal transduction [GO:0007265]; stress granule assembly [GO:0034063]; type I interferon production [GO:0032606]; viral process [GO:0016032]	axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; ribonucleoprotein complex [GO:1990904]	ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]
d1hkxh__d2xrxj___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]; ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron migration [GO:2001222]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neuron migration [GO:2001222]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]	aromatic compound catabolic process [GO:0019439]	axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]		ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1hkxj__d2f86b1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]; ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron migration [GO:2001222]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neuron migration [GO:2001222]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]	MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d1hkxn__d2ux0d___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]; ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron migration [GO:2001222]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; interferon-gamma-mediated signaling pathway [GO:0060333]; nervous system development [GO:0007399]; regulation of calcium ion transport [GO:0051924]; regulation of cellular response to heat [GO:1900034]; regulation of skeletal muscle adaptation [GO:0014733]	angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neuron migration [GO:2001222]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]	cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; interferon-gamma-mediated signaling pathway [GO:0060333]; nervous system development [GO:0007399]; regulation of calcium ion transport [GO:0051924]; regulation of cellular response to heat [GO:1900034]; regulation of skeletal muscle adaptation [GO:0014733]	axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum membrane [GO:0033017]	ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hl1a5_d1mdab___1				Proteobacteria		periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1hl1a5_d5onya1__1				Proteobacteria		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1hl2b__d3oexc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	3-dehydroquinate dehydratase activity [GO:0003855]
d1hl3a1_d1j4ad1__1	Metazoa		Chordata	Firmicutes	cell junction [GO:0030054]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; neuron projection [GO:0043005]; nucleus [GO:0005634]; presynapse [GO:0098793]; transcriptional repressor complex [GO:0017053]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; transferase activity, transferring acyl groups [GO:0016746]; membrane fusion [GO:0061025]; negative regulation of transcription, DNA-templated [GO:0045892]; presynapse to nucleus signaling pathway [GO:0099526]; white fat cell differentiation [GO:0050872]	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]	membrane fusion [GO:0061025]; negative regulation of transcription, DNA-templated [GO:0045892]; presynapse to nucleus signaling pathway [GO:0099526]; white fat cell differentiation [GO:0050872]		cell junction [GO:0030054]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; neuron projection [GO:0043005]; nucleus [GO:0005634]; presynapse [GO:0098793]; transcriptional repressor complex [GO:0017053]		NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; transferase activity, transferring acyl groups [GO:0016746]	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]
d1hl7a__d4upda1__1		Fungi	Actinobacteria	Ascomycota	peroxidase activity [GO:0004601]	hydrolase activity [GO:0016787]					peroxidase activity [GO:0004601]	hydrolase activity [GO:0016787]
d1hl7b__d1brta___1			Actinobacteria	Actinobacteria	peroxidase activity [GO:0004601]	peroxidase activity [GO:0004601]; antibiotic biosynthetic process [GO:0017000]		antibiotic biosynthetic process [GO:0017000]			peroxidase activity [GO:0004601]	peroxidase activity [GO:0004601]
d1hl7b__d1jfra___1			Actinobacteria	Actinobacteria	peroxidase activity [GO:0004601]	1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]			peroxidase activity [GO:0004601]	1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]
d1hl9b1_d4do4b2__1		Metazoa	Thermotogae	Chordata	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	lysosome [GO:0005764]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	alpha-L-fucosidase activity [GO:0004560]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d1hlca__d2w08b___1	Metazoa	Metazoa	Chordata	Chordata	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1hlcb__d3gala___1	Metazoa	Metazoa	Chordata	Chordata	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]
d1hlcb__d5jpgb___1	Metazoa	Metazoa	Chordata	Chordata	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	cytoplasm [GO:0005737]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; lymphatic endothelial cell migration [GO:1904977]		lymphatic endothelial cell migration [GO:1904977]		cytoplasm [GO:0005737]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d1hlda2_d2ydxd1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; methionine adenosyltransferase complex [GO:0048269]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; methionine adenosyltransferase regulator activity [GO:0048270]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; methionine adenosyltransferase complex [GO:0048269]; nucleus [GO:0005634]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	enzyme binding [GO:0019899]; methionine adenosyltransferase regulator activity [GO:0048270]
d1hlfa__d1jg7a___1	Metazoa		Chordata		skeletal muscle myofibril [GO:0098723]; glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]; glycogen metabolic process [GO:0005977]	DNA beta-glucosyltransferase activity [GO:0033821]; DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]	glycogen metabolic process [GO:0005977]	DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]	skeletal muscle myofibril [GO:0098723]		glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]	DNA beta-glucosyltransferase activity [GO:0033821]
d1hlka__d1ychb2__1			Bacteroidetes	Firmicutes	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1hlkb__d4f6za1__1			Bacteroidetes	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d1hlkb__d5k0wa___1			Bacteroidetes	Bacteroidetes	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1hlpa2_d1u5aa2__1			Euryarchaeota	Apicomplexa	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]		L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d1hlpb1_d1fxsa___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; GDP-L-fucose synthase activity [GO:0050577]; isomerase activity [GO:0016853]; NADP+ binding [GO:0070401]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; colanic acid biosynthetic process [GO:0009242]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; colanic acid biosynthetic process [GO:0009242]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	GDP-L-fucose synthase activity [GO:0050577]; isomerase activity [GO:0016853]; NADP+ binding [GO:0070401]
d1hlra5_d1pdxa___1				Proteobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1hlra5_d5c3jf1__1		Metazoa		Nematoda (roundworms)		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d1hlt.1_d1dx5.2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d1hlua2_d4h5wb1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; calyx of Held [GO:0044305]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dense body [GO:0097433]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic actin cytoskeleton [GO:0098871]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; nitric-oxide synthase binding [GO:0050998]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973]; Tat protein binding [GO:0030957]; axonogenesis [GO:0007409]; cell motility [GO:0048870]; cellular response to cytochalasin B [GO:0072749]; negative regulation of protein binding [GO:0032091]; regulation of norepinephrine uptake [GO:0051621]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of transmembrane transporter activity [GO:0022898]; synaptic vesicle endocytosis [GO:0048488]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	axonogenesis [GO:0007409]; cell motility [GO:0048870]; cellular response to cytochalasin B [GO:0072749]; negative regulation of protein binding [GO:0032091]; regulation of norepinephrine uptake [GO:0051621]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of transmembrane transporter activity [GO:0022898]; synaptic vesicle endocytosis [GO:0048488]	ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; calyx of Held [GO:0044305]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dense body [GO:0097433]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic actin cytoskeleton [GO:0098871]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; nitric-oxide synthase binding [GO:0050998]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973]; Tat protein binding [GO:0030957]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1hlup__d5nzba___1	Metazoa	Viridiplantae	Chordata	Streptophyta	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; calyx of Held [GO:0044305]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dense body [GO:0097433]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic actin cytoskeleton [GO:0098871]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; nitric-oxide synthase binding [GO:0050998]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973]; Tat protein binding [GO:0030957]; axonogenesis [GO:0007409]; cell motility [GO:0048870]; cellular response to cytochalasin B [GO:0072749]; negative regulation of protein binding [GO:0032091]; regulation of norepinephrine uptake [GO:0051621]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of transmembrane transporter activity [GO:0022898]; synaptic vesicle endocytosis [GO:0048488]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]	axonogenesis [GO:0007409]; cell motility [GO:0048870]; cellular response to cytochalasin B [GO:0072749]; negative regulation of protein binding [GO:0032091]; regulation of norepinephrine uptake [GO:0051621]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of transmembrane transporter activity [GO:0022898]; synaptic vesicle endocytosis [GO:0048488]		actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; calyx of Held [GO:0044305]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dense body [GO:0097433]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic actin cytoskeleton [GO:0098871]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; nitric-oxide synthase binding [GO:0050998]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973]; Tat protein binding [GO:0030957]	actin binding [GO:0003779]
d1hlwa__d5u2if1__1				Heterolobosea	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d1hm0b1_d3i3xa___1			Firmicutes	Spirochaetes	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]
d1hm2a2_d1rw9a2__1			Bacteroidetes	Actinobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]
d1hm2a3_d1j0ma3__1			Bacteroidetes	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	carbohydrate metabolic process [GO:0005975]	polysaccharide metabolic process [GO:0005976]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]
d1hm2a3_d3mv045__1			Bacteroidetes	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1hm3a3_d1rwga3__1			Bacteroidetes	Actinobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]
d1hm6b__d1xjlb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytoplasmic vesicle membrane [GO:0030659]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of endosome membrane [GO:0031313]; extrinsic component of external side of plasma membrane [GO:0031232]; lateral plasma membrane [GO:0016328]; motile cilium [GO:0031514]; nucleus [GO:0005634]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; phospholipase A2 inhibitor activity [GO:0019834]; actin cytoskeleton reorganization [GO:0031532]; adaptive immune response [GO:0002250]; alpha-beta T cell differentiation [GO:0046632]; arachidonic acid secretion [GO:0050482]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; DNA duplex unwinding [GO:0032508]; endocrine pancreas development [GO:0031018]; estrous cycle [GO:0044849]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gliogenesis [GO:0042063]; granulocyte chemotaxis [GO:0071621]; hepatocyte differentiation [GO:0070365]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; insulin secretion [GO:0030073]; keratinocyte differentiation [GO:0030216]; monocyte chemotaxis [GO:0002548]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of exocytosis [GO:0045920]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; neutrophil clearance [GO:0097350]; phagocytosis [GO:0006909]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; positive regulation of vesicle fusion [GO:0031340]; positive regulation of wound healing [GO:0090303]; prolactin secretion [GO:0070459]; prostate gland development [GO:0030850]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of hormone secretion [GO:0046883]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-1 production [GO:0032652]; regulation of leukocyte migration [GO:0002685]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to interleukin-1 [GO:0070555]; response to peptide hormone [GO:0043434]; response to X-ray [GO:0010165]	azurophil granule lumen [GO:0035578]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell cortex [GO:0005938]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; macropinosome [GO:0044354]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; myelin sheath adaxonal region [GO:0035749]; nucleus [GO:0005634]; PCSK9-AnxA2 complex [GO:1990667]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; sarcolemma [GO:0042383]; Schmidt-Lanterman incisure [GO:0043220]; vesicle [GO:0031982]; bone sialoprotein binding [GO:0044730]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; molecular function regulator [GO:0098772]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipase A2 inhibitor activity [GO:0019834]; protease binding [GO:0002020]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; virion binding [GO:0046790]; voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [GO:0099511]; angiogenesis [GO:0001525]; biomineral tissue development [GO:0031214]; body fluid secretion [GO:0007589]; catabolism by host of symbiont protein [GO:0052362]; collagen fibril organization [GO:0030199]; endocardial cell differentiation [GO:0060956]; fibrinolysis [GO:0042730]; growth plate cartilage development [GO:0003417]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane raft assembly [GO:0001765]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of development of symbiont involved in interaction with host [GO:0044147]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; neutrophil degranulation [GO:0043312]; osteoclast development [GO:0036035]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of low-density lipoprotein particle receptor binding [GO:1905597]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor recycling [GO:0001921]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of vacuole organization [GO:0044090]; positive regulation of vesicle fusion [GO:0031340]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; regulation of plasminogen activation [GO:0010755]; response to thyroid hormone [GO:0097066]; vesicle budding from membrane [GO:0006900]	actin cytoskeleton reorganization [GO:0031532]; adaptive immune response [GO:0002250]; alpha-beta T cell differentiation [GO:0046632]; arachidonic acid secretion [GO:0050482]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; DNA duplex unwinding [GO:0032508]; endocrine pancreas development [GO:0031018]; estrous cycle [GO:0044849]; gliogenesis [GO:0042063]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; granulocyte chemotaxis [GO:0071621]; hepatocyte differentiation [GO:0070365]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; insulin secretion [GO:0030073]; keratinocyte differentiation [GO:0030216]; monocyte chemotaxis [GO:0002548]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of exocytosis [GO:0045920]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; neutrophil clearance [GO:0097350]; phagocytosis [GO:0006909]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; positive regulation of vesicle fusion [GO:0031340]; positive regulation of wound healing [GO:0090303]; prolactin secretion [GO:0070459]; prostate gland development [GO:0030850]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of hormone secretion [GO:0046883]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-1 production [GO:0032652]; regulation of leukocyte migration [GO:0002685]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to interleukin-1 [GO:0070555]; response to peptide hormone [GO:0043434]; response to X-ray [GO:0010165]	angiogenesis [GO:0001525]; biomineral tissue development [GO:0031214]; body fluid secretion [GO:0007589]; catabolism by host of symbiont protein [GO:0052362]; collagen fibril organization [GO:0030199]; endocardial cell differentiation [GO:0060956]; fibrinolysis [GO:0042730]; growth plate cartilage development [GO:0003417]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane raft assembly [GO:0001765]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of development of symbiont involved in interaction with host [GO:0044147]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; neutrophil degranulation [GO:0043312]; osteoclast development [GO:0036035]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of low-density lipoprotein particle receptor binding [GO:1905597]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of receptor recycling [GO:0001921]; positive regulation of vacuole organization [GO:0044090]; positive regulation of vesicle fusion [GO:0031340]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; regulation of plasminogen activation [GO:0010755]; response to thyroid hormone [GO:0097066]; vesicle budding from membrane [GO:0006900]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytoplasmic vesicle membrane [GO:0030659]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of endosome membrane [GO:0031313]; extrinsic component of external side of plasma membrane [GO:0031232]; lateral plasma membrane [GO:0016328]; motile cilium [GO:0031514]; nucleus [GO:0005634]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]	azurophil granule lumen [GO:0035578]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; macropinosome [GO:0044354]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; myelin sheath adaxonal region [GO:0035749]; nucleus [GO:0005634]; PCSK9-AnxA2 complex [GO:1990667]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; sarcolemma [GO:0042383]; Schmidt-Lanterman incisure [GO:0043220]; vesicle [GO:0031982]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; phospholipase A2 inhibitor activity [GO:0019834]	bone sialoprotein binding [GO:0044730]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium channel activity [GO:0005262]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; molecular function regulator [GO:0098772]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipase A2 inhibitor activity [GO:0019834]; protease binding [GO:0002020]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; virion binding [GO:0046790]; voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [GO:0099511]
d1hm8a1_d1khrd___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	transferase activity, transferring acyl groups [GO:0016746]
d1hm8b2_d4b2xb1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytoplasm [GO:0005737]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1hm9a1_d1yp2b1__1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	amyloplast [GO:0009501]; chloroplast [GO:0009507]; ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]; glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cytoplasm [GO:0005737]	amyloplast [GO:0009501]; chloroplast [GO:0009507]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]
d1hmda__d1hrbb___1	Metazoa	Metazoa	Annelida	Annelida	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]					iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]
d1hmdc__d1hrba___1	Metazoa	Metazoa	Annelida	Annelida	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]					iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]
d1hmka__d191la___1	Metazoa		Chordata		extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; lactose biosynthetic process [GO:0005989]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	lactose biosynthetic process [GO:0005989]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]	host cell cytoplasm [GO:0030430]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]	lysozyme activity [GO:0003796]
d1hmla__d4ngwa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1hmra__d2f73d2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]
d1hmra__d4zfxc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1hmsa__d3fw5c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1hmsa__d3p6da1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1hmta__d1fena___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	extracellular space [GO:0005615]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	extracellular space [GO:0005615]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]	retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]
d1hmua2_d2e22a2__1			Bacteroidetes	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	carbohydrate metabolic process [GO:0005975]	polysaccharide metabolic process [GO:0005976]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]
d1hmua3_d3d50a2__1		Metazoa	Bacteroidetes	Arthropoda	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1hmve1_d3lala2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hmwa3_d1rwfa3__1			Bacteroidetes	Actinobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]
d1hmwa3_d5a1aa5__1			Bacteroidetes	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1hn0a1_d1n7ra1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; chondroitin-sulfate-ABC endolyase activity [GO:0034000]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; glycosaminoglycan catabolic process [GO:0006027]	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; glycosaminoglycan catabolic process [GO:0006027]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; periplasmic space [GO:0042597]	cell wall [GO:0005618]; extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; chondroitin-sulfate-ABC endolyase activity [GO:0034000]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d1hn1a4_d2alwa2__1		Metazoa	Proteobacteria	Arthropoda	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1hn1b2_d4jkka2__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1hn1b4_d4duvd5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1hn1c3_d2wyfg___1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	lactose catabolic process [GO:0005990]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	beta-galactosidase complex [GO:0009341]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]
d1hn1c5_d5eb8a___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]
d1hn1d3_d1ryyf1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d1hn2b__d3fa8a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	extracellular region [GO:0005576]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1hn9a1_d2cdha2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1hn9a2_d2bz3a1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1hn9b1_d4o9ab1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1hnaa1_d1n2aa1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; response to hydrogen peroxide [GO:0042542]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytoplasm [GO:0005737]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione transferase activity [GO:0004364]
d1hnba1_d5aixc2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1hnca1_d1gsfb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1hnca2_d1tk0b___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1hnca2_d1v2ac2__1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	glutathione transferase activity [GO:0004364]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione transferase activity [GO:0004364]
d1hncb2_d6gswa2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d1hncc2_d5gzzg1__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	glutathione transferase activity [GO:0004364]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione transferase activity [GO:0004364]
d1hncd1_d2vcvj2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione transferase activity [GO:0004364]
d1hnfa1_d4xp6l1__1	Metazoa	Metazoa	Chordata	Arthropoda	anchored component of plasma membrane [GO:0046658]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; membrane raft polarization [GO:0001766]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of T cell differentiation [GO:0045580]; T cell activation [GO:0042110]	integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]; adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	apoptotic process [GO:0006915]; cell-cell adhesion [GO:0098609]; cell surface receptor signaling pathway [GO:0007166]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; membrane raft polarization [GO:0001766]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of T cell differentiation [GO:0045580]; T cell activation [GO:0042110]	adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	anchored component of plasma membrane [GO:0046658]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	integral component of plasma membrane [GO:0005887]; neuronal cell body membrane [GO:0032809]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]	cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]
d1hnfa2_d4l29z1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of plasma membrane [GO:0046658]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; membrane raft polarization [GO:0001766]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of T cell differentiation [GO:0045580]; T cell activation [GO:0042110]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	apoptotic process [GO:0006915]; cell-cell adhesion [GO:0098609]; cell surface receptor signaling pathway [GO:0007166]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; membrane raft polarization [GO:0001766]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of T cell differentiation [GO:0045580]; T cell activation [GO:0042110]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	anchored component of plasma membrane [GO:0046658]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hnga2_d2iepb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; protein-containing complex [GO:0032991]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of tumor necrosis factor production [GO:0032760]; T cell activation [GO:0042110]	cell junction [GO:0030054]; cell projection [GO:0042995]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; cochlea development [GO:0090102]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to muscle activity [GO:0014850]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of tumor necrosis factor production [GO:0032760]; T cell activation [GO:0042110]	cochlea development [GO:0090102]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to muscle activity [GO:0014850]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; protein-containing complex [GO:0032991]	cell junction [GO:0030054]; cell projection [GO:0042995]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]	protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1hngb2_d3tcll1__1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; protein-containing complex [GO:0032991]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of tumor necrosis factor production [GO:0032760]; T cell activation [GO:0042110]		cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of tumor necrosis factor production [GO:0032760]; T cell activation [GO:0042110]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; protein-containing complex [GO:0032991]		protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]	
d1hnia1_d1c0mc2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; reverse transcription [GO:0001171]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; reverse transcription [GO:0001171]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	viral nucleocapsid [GO:0019013]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d1hnja2_d1u0mb2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; melanin biosynthetic process [GO:0042438]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	melanin biosynthetic process [GO:0042438]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1hnwb__d2z4kb1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1hnwe1_d2j65a2__1			Deinococcus-Thermus	Aquificae	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	translation [GO:0006412]	lipid A biosynthetic process [GO:0009245]	ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d1hnwk__d1ffkk___1			Deinococcus-Thermus	Euryarchaeota	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1hnwq__d2e5lq1__1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1hnxb__d1vi6b___1			Deinococcus-Thermus	Euryarchaeota	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	small ribosomal subunit [GO:0015935]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	small ribosomal subunit [GO:0015935]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	structural constituent of ribosome [GO:0003735]
d1hnxe1_d2jt2a2__1			Deinococcus-Thermus	Aquificae	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	translation [GO:0006412]	lipid A biosynthetic process [GO:0009245]	ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d1hnxp__d3df3p1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1hnya1_d2f2hf3__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1hnya2_d3t09c3__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	lactose catabolic process [GO:0005990]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	beta-galactosidase complex [GO:0009341]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1hnzq__d3df1l1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1ho3b__d5f52d___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]; asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]	asparaginase activity [GO:0004067]; asparagine metabolic process [GO:0006528]	asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]	asparagine metabolic process [GO:0006528]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]	asparaginase activity [GO:0004067]
d1ho5b2_d2nylf1__1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	nucleotide catabolic process [GO:0009166]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	outer membrane-bounded periplasmic space [GO:0030288]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]	GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]
d1hoca1_d1wwwx___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]
d1hoca1_d3kpsa2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hoca2_d1jwma2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1hocb__d4qhua2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cell-cell signaling [GO:0007267]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cell death [GO:0008219]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	cytokine activity [GO:0005125]
d1hocb__d5hvfb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; blood coagulation [GO:0007596]; cellular response to glucose stimulus [GO:0071333]; fibrinolysis [GO:0042730]; liver regeneration [GO:0097421]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of plasminogen activation [GO:0010757]; positive regulation of extracellular matrix constituent secretion [GO:0003331]; proteolysis [GO:0006508]; regulation of complement activation [GO:0030449]; response to drug [GO:0042493]; response to heat [GO:0009408]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood coagulation [GO:0007596]; cellular response to glucose stimulus [GO:0071333]; fibrinolysis [GO:0042730]; liver regeneration [GO:0097421]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of plasminogen activation [GO:0010757]; positive regulation of extracellular matrix constituent secretion [GO:0003331]; proteolysis [GO:0006508]; regulation of complement activation [GO:0030449]; response to drug [GO:0042493]; response to heat [GO:0009408]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1hora__d1ne7c___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; single fertilization [GO:0007338]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; single fertilization [GO:0007338]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]	glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]
d1hp4a2_d4c7ga1__1			Actinobacteria	Actinobacteria	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			beta-N-acetylhexosaminidase activity [GO:0004563]	beta-N-acetylhexosaminidase activity [GO:0004563]
d1hpbp__d3b7de___1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; amino acid transport [GO:0006865]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	amino acid transport [GO:0006865]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1hpcb__d3wdna___1	Viridiplantae	Metazoa	Streptophyta	Chordata	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]; glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]; glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]		
d1hpga__d2sgde___1		Metazoa	Actinobacteria	Chordata	serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]				extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1hpma2_d1mwmb2__1	Metazoa		Chordata	Proteobacteria	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	identical protein binding [GO:0042802]; plasmid partitioning [GO:0030541]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	plasmid partitioning [GO:0030541]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	identical protein binding [GO:0042802]
d1hpsa__d5p05a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hpsb__d3qbfb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hpsb__d5p71a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hpuc2_d4b2oc___1			Proteobacteria	Firmicutes	outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]	cytoplasm [GO:0005737]; 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]	nucleotide catabolic process [GO:0009166]		outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]
d1hpud2_d1z2wb___1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]	cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer complex [GO:0030904]; retromer, cargo-selective complex [GO:0030906]; metal ion binding [GO:0046872]; endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]	nucleotide catabolic process [GO:0009166]	endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]	outer membrane-bounded periplasmic space [GO:0030288]	cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer, cargo-selective complex [GO:0030906]; retromer complex [GO:0030904]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]	metal ion binding [GO:0046872]
d1hpva__d1epme___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hpvb__d4dqba___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hpxa__d5kqza___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hq0a__d1hzga___1			Proteobacteria	Proteobacteria								
d1hq3c__d3azja___1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleosome [GO:0000786]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1hq4a2_d1y0lc1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1hq4b1_d5hysb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1hq4c1_d1u95a1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1hq4c1_d5wk3r1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR4 chemokine receptor binding [GO:0031729]; chemokine activity [GO:0008009]; signaling receptor binding [GO:0005102]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; multicellular organism development [GO:0007275]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil chemotaxis [GO:0030593]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; multicellular organism development [GO:0007275]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil chemotaxis [GO:0030593]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	CCR4 chemokine receptor binding [GO:0031729]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; signaling receptor binding [GO:0005102]
d1hq4d1_d1lk2a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1hq5b__d3nipb___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]
d1hqba__d4ihgk___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; D-alanyl carrier activity [GO:0036370]; cell wall organization [GO:0071555]; lipoteichoic acid biosynthetic process [GO:0070395]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acyltransferase activity [GO:0016410]; UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity [GO:0103118]; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity [GO:0043764]; lipid A biosynthetic process [GO:0009245]; response to antibiotic [GO:0046677]	cell wall organization [GO:0071555]; lipoteichoic acid biosynthetic process [GO:0070395]	lipid A biosynthetic process [GO:0009245]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	D-alanyl carrier activity [GO:0036370]	identical protein binding [GO:0042802]; N-acyltransferase activity [GO:0016410]; UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity [GO:0103118]; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity [GO:0043764]
d1hqca2_d1xxhh2__1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA-dependent DNA replication [GO:0006261]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	DNA-dependent DNA replication [GO:0006261]		DNA polymerase III complex [GO:0009360]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1hqcb2_d1xtka2__1		Metazoa	Deinococcus-Thermus	Chordata	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; transcription export complex [GO:0000346]; ATP binding [GO:0005524]; ATP-dependent protein binding [GO:0043008]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-dependent ATPase activity [GO:0008186]; U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070]; liver development [GO:0001889]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; RNA export from nucleus [GO:0006405]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	liver development [GO:0001889]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; RNA export from nucleus [GO:0006405]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784]		cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; transcription export complex [GO:0000346]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; ATP-dependent protein binding [GO:0043008]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; RNA helicase activity [GO:0003724]; U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070]
d1hqda__d1etha2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; enzyme activator activity [GO:0008047]; digestion [GO:0007586]; lipid catabolic process [GO:0016042]; response to bacterium [GO:0009617]; response to food [GO:0032094]	lipid catabolic process [GO:0016042]	digestion [GO:0007586]; lipid catabolic process [GO:0016042]; response to bacterium [GO:0009617]; response to food [GO:0032094]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	enzyme activator activity [GO:0008047]
d1hqea1_d1ikya1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hqha__d4qa0a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]
d1hqhb__d1p8qb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1hqkb__d1rvvn___1			Aquificae	Firmicutes	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1hqkd__d4geff___1			Aquificae		cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]		cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]		6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	
d1hqlb__d3ap6a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d1hqpa__d5hz6a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	small molecule binding [GO:0036094]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1hqra2_d5d5ma1__1	Metazoa	Metazoa	Chordata	Chordata	cell periphery [GO:0071944]; cell surface [GO:0009986]; compact myelin [GO:0043218]; internode region of axon [GO:0033269]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; calmodulin binding [GO:0005516]; protease binding [GO:0002020]; structural constituent of myelin sheath [GO:0019911]; axon ensheathment [GO:0008366]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; immune response [GO:0006955]; maintenance of permeability of blood-brain barrier [GO:0035633]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; myelination [GO:0042552]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; positive regulation of chemokine (C-C motif) ligand 2 secretion [GO:1904209]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of metalloendopeptidase activity [GO:1904685]; response to toxic substance [GO:0009636]; sensory perception of sound [GO:0007605]; substantia nigra development [GO:0021762]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	axon ensheathment [GO:0008366]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; immune response [GO:0006955]; maintenance of permeability of blood-brain barrier [GO:0035633]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; myelination [GO:0042552]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; positive regulation of chemokine (C-C motif) ligand 2 secretion [GO:1904209]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of metalloendopeptidase activity [GO:1904685]; response to toxic substance [GO:0009636]; sensory perception of sound [GO:0007605]; substantia nigra development [GO:0021762]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell periphery [GO:0071944]; cell surface [GO:0009986]; compact myelin [GO:0043218]; internode region of axon [GO:0033269]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	calmodulin binding [GO:0005516]; protease binding [GO:0002020]; structural constituent of myelin sheath [GO:0019911]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hqrb2_d4qrra1__1	Metazoa	Metazoa	Chordata	Chordata	cell periphery [GO:0071944]; cell surface [GO:0009986]; compact myelin [GO:0043218]; internode region of axon [GO:0033269]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; calmodulin binding [GO:0005516]; protease binding [GO:0002020]; structural constituent of myelin sheath [GO:0019911]; axon ensheathment [GO:0008366]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; immune response [GO:0006955]; maintenance of permeability of blood-brain barrier [GO:0035633]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; myelination [GO:0042552]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; positive regulation of chemokine (C-C motif) ligand 2 secretion [GO:1904209]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of metalloendopeptidase activity [GO:1904685]; response to toxic substance [GO:0009636]; sensory perception of sound [GO:0007605]; substantia nigra development [GO:0021762]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	axon ensheathment [GO:0008366]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; immune response [GO:0006955]; maintenance of permeability of blood-brain barrier [GO:0035633]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; myelination [GO:0042552]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; positive regulation of chemokine (C-C motif) ligand 2 secretion [GO:1904209]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of metalloendopeptidase activity [GO:1904685]; response to toxic substance [GO:0009636]; sensory perception of sound [GO:0007605]; substantia nigra development [GO:0021762]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell periphery [GO:0071944]; cell surface [GO:0009986]; compact myelin [GO:0043218]; internode region of axon [GO:0033269]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	calmodulin binding [GO:0005516]; protease binding [GO:0002020]; structural constituent of myelin sheath [GO:0019911]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hqwa__d4y26a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1hqxa__d4ixva___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1hqxa__d5eeib___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]
d1hqxb__d1t4sa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1hqxc__d3mjlb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1hqyb__d1rypu___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1hqyc__d3nzxt___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1hqyc__d5cz8s___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1hqz2__d2fh3c2__1	Fungi	Metazoa	Ascomycota	Chordata	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin filament binding [GO:0051015]; actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament binding [GO:0051015]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1hqz3__d2fh4b2__1	Fungi	Metazoa	Ascomycota	Chordata	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin filament binding [GO:0051015]; actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament binding [GO:0051015]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1hqz5__d1f7sa___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin filament binding [GO:0051015]; actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]	actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin filament depolymerization [GO:0030042]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]	actin filament binding [GO:0051015]	actin binding [GO:0003779]
d1hqz6__d2fh1a1__1	Fungi	Metazoa	Ascomycota	Chordata	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin filament binding [GO:0051015]; actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament binding [GO:0051015]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1hqz7__d1d0na6__1	Fungi	Metazoa	Ascomycota	Chordata	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin filament binding [GO:0051015]; actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin filament binding [GO:0051015]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d1hqz9__d3ffnb3__1	Fungi	Metazoa	Ascomycota	Chordata	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin filament binding [GO:0051015]; actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament binding [GO:0051015]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1hr0e1_d2uxci1__1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1hr6c2_d1q2la1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	proteolysis [GO:0006508]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1hr6d2_d3l72n1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	protein processing involved in protein targeting to mitochondrion [GO:0006627]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1hr6e2_d4xchd___1	Fungi		Ascomycota	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]; quorum sensing [GO:0009372]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	quorum sensing [GO:0009372]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]
d1hr6f2_d1kyoa2__1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1hr7a1_d1kyol1__1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1hr7b1_d1hr6a2__1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1hr7b1_d4xcha___1	Fungi		Ascomycota	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]; quorum sensing [GO:0009372]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	quorum sensing [GO:0009372]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]
d1hr7b2_d1q2la4__1	Fungi		Ascomycota	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	proteolysis [GO:0006508]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1hr7d2_d1vh2a___1	Fungi		Ascomycota	Deinococcus-Thermus	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]; quorum sensing [GO:0009372]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	quorum sensing [GO:0009372]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]
d1hr7e1_d3h1jn2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	protein processing involved in protein targeting to mitochondrion [GO:0006627]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1hr7h1_d3l72o1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	protein processing involved in protein targeting to mitochondrion [GO:0006627]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1hr8b1_d3h1hb1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	protein processing involved in protein targeting to mitochondrion [GO:0006627]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1hr8d1_d3h1jn1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	protein processing involved in protein targeting to mitochondrion [GO:0006627]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1hr8d2_d3l73b2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	protein processing involved in protein targeting to mitochondrion [GO:0006627]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1hr8e1_d3l70b2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	protein processing involved in protein targeting to mitochondrion [GO:0006627]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1hr8f2_d3l73o1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	protein processing involved in protein targeting to mitochondrion [GO:0006627]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1hr8g1_d3l71n2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	protein processing involved in protein targeting to mitochondrion [GO:0006627]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1hr9b1_d3l72a1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]; aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1hr9b2_d1joed___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]; aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]; quorum sensing [GO:0009372]	aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	quorum sensing [GO:0009372]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]
d1hrda2_d1nqtf2__1		Metazoa	Firmicutes	Chordata	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase (NAD+) activity [GO:0004352]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1hrdb1_d4ijwa___1		Metazoa	Firmicutes	Chordata	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	glutamate dehydrogenase (NAD+) activity [GO:0004352]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d1hrdb2_d1c1db2__1			Firmicutes	Actinobacteria	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]			glutamate dehydrogenase (NAD+) activity [GO:0004352]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d1hrdc1_d5jydb___1			Firmicutes	Proteobacteria	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]				glutamate dehydrogenase (NAD+) activity [GO:0004352]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1hri1__d1c8na___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1hri.1_d1f15a___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1hrka__d3hcrb___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d1hrkb__d1tjna___1	Metazoa		Chordata	Euryarchaeota	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]; anaerobic cobalamin biosynthetic process [GO:0019251]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	anaerobic cobalamin biosynthetic process [GO:0019251]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]
d1hroa__d3nwvb___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]	photosynthesis [GO:0015979]	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1hrv.1_d4cdwb___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1hs6a2_d4fkka1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1hsaa2_d4pjaa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hsae__d3pwpd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hsba1_d2w0kb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1hsba1_d4g8fb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1hsbb__d1egjh1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1hsea__d1h45a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d1hsga__d5p25a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hsgb__d5p7wa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hshb__d3fv3g___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hsib__d5dpza___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hsjb2_d3tcgb___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]
d1hsjb2_d5nf5b___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d1hsra__d5sx3a1__1	Fungi		Basidiomycota	Proteobacteria	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1hsxa__d4cged___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	hydrolase activity [GO:0016787]
d1ht1c__d5jhss___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ht1y__d5l6bq___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ht1z__d4r02y___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ht2a__d4quxc___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ht3a__d1siua___1	Fungi		Ascomycota	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1ht5a1_d3vlja2__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]		dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1htaa__d3azld___1		Metazoa	Euryarchaeota	Chordata	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; DNA topological change [GO:0006265]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	DNA topological change [GO:0006265]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	double-stranded DNA binding [GO:0003690]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1htba2_d5vl0b2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1htda__d2w14a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; collagen catabolic process [GO:0030574]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; chemotaxis [GO:0006935]	collagen catabolic process [GO:0030574]	chemotaxis [GO:0006935]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]
d1htdb__d3p7re___1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; collagen catabolic process [GO:0030574]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	collagen catabolic process [GO:0030574]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1htfa__d5p2na___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1htfb__d5b18a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d1htga__d3tkga___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1htgb__d1odxa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1htib__d4unka___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]
d1htld__d1rcvg___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	toxin activity [GO:0090729]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d1htle__d5tssa1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1htlg__d1fnvc1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1htlh__d4o1nf1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; peptidase activity [GO:0008233]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	peptidase activity [GO:0008233]
d1htoc1_d2glsd1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d1htof1_d4lnnc1__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1htof2_d3l2fm2__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	
d1htoi1_d4lnof1__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1htoj2_d3l2fk2__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	
d1htom2_d1vrpa2__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	phosphocreatine biosynthetic process [GO:0046314]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d1hton2_d3l2gg2__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	
d1htoq2_d4lnka2__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1htos2_d4lnfb2__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1htot1_d1fpyi1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d1htov1_d4lnnh1__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1htow2_d3zxvd2__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1htox2_d1fpyl2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d1htpa__d1iyua___1	Viridiplantae		Streptophyta	Proteobacteria	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]; glycine decarboxylation via glycine cleavage system [GO:0019464]	pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	glycine decarboxylation via glycine cleavage system [GO:0019464]	glycolytic process [GO:0006096]	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]	pyruvate dehydrogenase complex [GO:0045254]		dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]
d1htqa2_d1fpyk2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d1htqa2_d4lnfc2__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1htqc1_d3qajb1__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	
d1htqd2_d4lnib2__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1htqf1_d2bvcb1__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1htqg1_d4lnfd1__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1htqh2_d3l2fo2__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	
d1htqj1_d3qajj1__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	
d1htql1_d1f52j1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d1htql2_d3jpza2__1		Metazoa	Actinobacteria	Annelida	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	phosphocreatine biosynthetic process [GO:0046314]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d1htqm2_d4lnfk2__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1htqo2_d3l2gc2__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	
d1htqp2_d4lnoc2__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1htqr2_d3l2gm2__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	
d1htqs1_d4lnid1__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1htqs2_d4lnkd2__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1htqt1_d4acfb1__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1htqu2_d2whif2__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1htr.1_d5p8oa___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular space [GO:0005615]; aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; positive regulation of antibacterial peptide production [GO:0002803]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	aspartic-type endopeptidase activity [GO:0004190]	digestion [GO:0007586]; positive regulation of antibacterial peptide production [GO:0002803]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		extracellular space [GO:0005615]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1httb1_d4p3pa2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	histidyl-tRNA aminoacylation [GO:0006427]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1httd1_d1kogd1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	histidyl-tRNA aminoacylation [GO:0006427]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1httd1_d4eo4a2__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; mitochondrial threonyl-tRNA aminoacylation [GO:0070159]; threonyl-tRNA aminoacylation [GO:0006435]	histidyl-tRNA aminoacylation [GO:0006427]	mitochondrial threonyl-tRNA aminoacylation [GO:0070159]; threonyl-tRNA aminoacylation [GO:0006435]	cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]	ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]
d1htwc__d1cp2b___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]	molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1hu8a__d3kmdc___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; central nervous system development [GO:0007417]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; chromosome organization [GO:0051276]; circadian behavior [GO:0048512]; circadian rhythm [GO:0007623]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; heart development [GO:0007507]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of mitophagy [GO:1901525]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron apoptotic process [GO:0043523]; regulation of thymocyte apoptotic process [GO:0070243]; regulation of tissue remodeling [GO:0034103]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to caffeine [GO:0031000]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to oxidative stress [GO:0006979]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	apoptotic process [GO:0006915]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; central nervous system development [GO:0007417]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; chromosome organization [GO:0051276]; circadian behavior [GO:0048512]; circadian rhythm [GO:0007623]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; heart development [GO:0007507]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of mitophagy [GO:1901525]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron apoptotic process [GO:0043523]; regulation of thymocyte apoptotic process [GO:0070243]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to caffeine [GO:0031000]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to oxidative stress [GO:0006979]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1hu9a2_d3v99a1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; oxylipin biosynthetic process [GO:0031408]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nuclear envelope [GO:0005635]; nuclear envelope lumen [GO:0005641]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]; arachidonate 5-lipoxygenase activity [GO:0004051]; iron ion binding [GO:0005506]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-18-mediated signaling pathway [GO:0035655]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]	oxylipin biosynthetic process [GO:0031408]	cytokine-mediated signaling pathway [GO:0019221]; interleukin-18-mediated signaling pathway [GO:0035655]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nuclear envelope [GO:0005635]; nuclear envelope lumen [GO:0005641]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]	metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]	arachidonate 5-lipoxygenase activity [GO:0004051]; iron ion binding [GO:0005506]
d1huea__d1ouzb___1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]	chromosome [GO:0005694]; cytosol [GO:0005829]; DNA binding [GO:0003677]; conjugation [GO:0000746]; DNA recombination [GO:0006310]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]	chromosome condensation [GO:0030261]	conjugation [GO:0000746]; DNA recombination [GO:0006310]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]		chromosome [GO:0005694]; cytosol [GO:0005829]	DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1huga__d1jcza___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; chloride ion homeostasis [GO:0055064]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	bicarbonate transport [GO:0015701]; chloride ion homeostasis [GO:0055064]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1hukb__d4z74d1__1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1humb__d2fj2b1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR1 chemokine receptor binding [GO:0031726]; CCR5 chemokine receptor binding [GO:0031730]; chemokine activity [GO:0008009]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; establishment or maintenance of cell polarity [GO:0007163]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; neutrophil chemotaxis [GO:0030593]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of natural killer cell chemotaxis [GO:2000503]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; signal transduction [GO:0007165]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; chemokine activity [GO:0008009]; CXCR chemokine receptor binding [GO:0045236]; immune response [GO:0006955]	cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; establishment or maintenance of cell polarity [GO:0007163]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; neutrophil chemotaxis [GO:0030593]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of natural killer cell chemotaxis [GO:2000503]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; signal transduction [GO:0007165]	immune response [GO:0006955]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	CCR1 chemokine receptor binding [GO:0031726]; CCR5 chemokine receptor binding [GO:0031730]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]	chemokine activity [GO:0008009]; CXCR chemokine receptor binding [GO:0045236]
d1huoa4_d2dr8a2__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]		damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]
d1hupa1_d3g4nb1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; innate immune response [GO:0045087]; killing by host of symbiont cells [GO:0051873]; negative regulation of viral process [GO:0048525]; opsonization [GO:0008228]; positive regulation of phagocytosis [GO:0050766]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	acute-phase response [GO:0006953]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; innate immune response [GO:0045087]; killing by host of symbiont cells [GO:0051873]; negative regulation of viral process [GO:0048525]; opsonization [GO:0008228]; positive regulation of phagocytosis [GO:0050766]; response to oxidative stress [GO:0006979]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]	calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; signaling receptor binding [GO:0005102]	identical protein binding [GO:0042802]; toxin activity [GO:0090729]
d1hut.1_d3sjoc___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1huua__d1p78b___1			Firmicutes	Cyanobacteria	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]	chromosome condensation [GO:0030261]	chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1huub__d3rhia___1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]	chromosome condensation [GO:0030261]	chromosome condensation [GO:0030261]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1huuc__d4dkyb1__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; double-stranded DNA binding [GO:0003690]; supercoiled DNA binding [GO:0097100]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; cellular response to iron ion starvation [GO:0010106]; chromosome condensation [GO:0030261]; DNA protection [GO:0042262]; nucleoid organization [GO:0090143]; positive regulation of transcription, DNA-templated [GO:0045893]	chromosome condensation [GO:0030261]	cellular response to iron ion starvation [GO:0010106]; chromosome condensation [GO:0030261]; DNA protection [GO:0042262]; nucleoid organization [GO:0090143]; positive regulation of transcription, DNA-templated [GO:0045893]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; double-stranded DNA binding [GO:0003690]; supercoiled DNA binding [GO:0097100]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1hv4d__d1f99b___1	Metazoa		Chordata	Rhodophyta	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1hv4d__d4irob___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1hv5c__d1qf1a___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; basement membrane organization [GO:0071711]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; negative regulation of fat cell differentiation [GO:0045599]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	basement membrane organization [GO:0071711]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; negative regulation of fat cell differentiation [GO:0045599]		extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1hv5d__d6tmne___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; basement membrane organization [GO:0071711]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; negative regulation of fat cell differentiation [GO:0045599]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	basement membrane organization [GO:0071711]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; negative regulation of fat cell differentiation [GO:0045599]		extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1hv5e__d5d2ba1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; basement membrane organization [GO:0071711]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; negative regulation of fat cell differentiation [GO:0045599]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	basement membrane organization [GO:0071711]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; negative regulation of fat cell differentiation [GO:0045599]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1hv5f__d2isgb___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; basement membrane organization [GO:0071711]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; negative regulation of fat cell differentiation [GO:0045599]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	basement membrane organization [GO:0071711]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; negative regulation of fat cell differentiation [GO:0045599]	negative regulation of neurotransmitter secretion [GO:0046929]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1hv9b2_d2y4mb___1			Proteobacteria	Bacteroidetes	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytosol [GO:0005829]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	
d1hvca2_d1odyb___1					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hvfa__d1dm5a___1	Metazoa	Metazoa	Chordata	Cnidaria	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]		calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]
d1hvfa__d2hywa___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	azurophil granule lumen [GO:0035578]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell cortex [GO:0005938]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; macropinosome [GO:0044354]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; myelin sheath adaxonal region [GO:0035749]; nucleus [GO:0005634]; PCSK9-AnxA2 complex [GO:1990667]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; sarcolemma [GO:0042383]; Schmidt-Lanterman incisure [GO:0043220]; vesicle [GO:0031982]; bone sialoprotein binding [GO:0044730]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; molecular function regulator [GO:0098772]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipase A2 inhibitor activity [GO:0019834]; protease binding [GO:0002020]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; virion binding [GO:0046790]; voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [GO:0099511]; angiogenesis [GO:0001525]; biomineral tissue development [GO:0031214]; body fluid secretion [GO:0007589]; catabolism by host of symbiont protein [GO:0052362]; collagen fibril organization [GO:0030199]; endocardial cell differentiation [GO:0060956]; fibrinolysis [GO:0042730]; growth plate cartilage development [GO:0003417]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane raft assembly [GO:0001765]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of development of symbiont involved in interaction with host [GO:0044147]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; neutrophil degranulation [GO:0043312]; osteoclast development [GO:0036035]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of low-density lipoprotein particle receptor binding [GO:1905597]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor recycling [GO:0001921]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of vacuole organization [GO:0044090]; positive regulation of vesicle fusion [GO:0031340]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; regulation of plasminogen activation [GO:0010755]; response to thyroid hormone [GO:0097066]; vesicle budding from membrane [GO:0006900]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; biomineral tissue development [GO:0031214]; body fluid secretion [GO:0007589]; catabolism by host of symbiont protein [GO:0052362]; collagen fibril organization [GO:0030199]; endocardial cell differentiation [GO:0060956]; fibrinolysis [GO:0042730]; growth plate cartilage development [GO:0003417]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane raft assembly [GO:0001765]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of development of symbiont involved in interaction with host [GO:0044147]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; neutrophil degranulation [GO:0043312]; osteoclast development [GO:0036035]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of low-density lipoprotein particle receptor binding [GO:1905597]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of receptor recycling [GO:0001921]; positive regulation of vacuole organization [GO:0044090]; positive regulation of vesicle fusion [GO:0031340]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; regulation of plasminogen activation [GO:0010755]; response to thyroid hormone [GO:0097066]; vesicle budding from membrane [GO:0006900]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]	azurophil granule lumen [GO:0035578]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; macropinosome [GO:0044354]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; myelin sheath adaxonal region [GO:0035749]; nucleus [GO:0005634]; PCSK9-AnxA2 complex [GO:1990667]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; sarcolemma [GO:0042383]; Schmidt-Lanterman incisure [GO:0043220]; vesicle [GO:0031982]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]	bone sialoprotein binding [GO:0044730]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium channel activity [GO:0005262]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; molecular function regulator [GO:0098772]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipase A2 inhibitor activity [GO:0019834]; protease binding [GO:0002020]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; virion binding [GO:0046790]; voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [GO:0099511]
d1hvha__d1ebzb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hvib__d5p1ma___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hvja__d1psab___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hvka__d1lyb.2__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	collagen-containing extracellular matrix [GO:0062023]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane raft [GO:0045121]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; aspartic-type endopeptidase activity [GO:0004190]; aspartic-type peptidase activity [GO:0070001]; peptidase activity [GO:0008233]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; collagen catabolic process [GO:0030574]; lipoprotein catabolic process [GO:0042159]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of establishment of protein localization [GO:0070201]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; collagen catabolic process [GO:0030574]; lipoprotein catabolic process [GO:0042159]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of establishment of protein localization [GO:0070201]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	collagen-containing extracellular matrix [GO:0062023]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane raft [GO:0045121]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; aspartic-type peptidase activity [GO:0070001]; peptidase activity [GO:0008233]
d1hvla__d4phva___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hvla__d5p0ca___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hvlb__d1c6zb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hvsb__d3pwra___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hvsb__d5p74a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hvud1_d1zbia___1				Firmicutes	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1hvud1_d3lp2a2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hvuj1_d5dzmb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1hw1b1_d2hs5a1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; fatty-acyl-CoA binding [GO:0000062]; fatty acid oxidation [GO:0019395]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fatty acid metabolic process [GO:0019217]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	fatty acid oxidation [GO:0019395]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fatty acid metabolic process [GO:0019217]		cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; fatty-acyl-CoA binding [GO:0000062]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1hwna__d3hiwa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; metabolic process [GO:0008152]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; metabolic process [GO:0008152]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1hwra__d2qi3a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1hwra__d5p6ea___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	aspartic-type endopeptidase activity [GO:0004190]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1hwwa2_d4duvb5__1	Metazoa		Arthropoda	Proteobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	beta-galactosidase complex [GO:0009341]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1hwxb4_d1bvue1__1				Euryarchaeota		cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]		cytoplasm [GO:0005737]		glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d1hwxc4_d3etdb2__1		Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1hwxc4_d5uavc1__1		Metazoa		Chordata		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]		cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1hwxd3_d5ijzc1__1				Actinobacteria		cytoplasm [GO:0005737]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; glutamate biosynthetic process [GO:0006537]		glutamate biosynthetic process [GO:0006537]		cytoplasm [GO:0005737]		glutamate dehydrogenase (NADP+) activity [GO:0004354]
d1hwxd4_d2pd4a___1				Proteobacteria		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]		fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]				enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]
d1hwza1_d3mvqf2__1												
d1hwzb1_d3mvqa2__1												
d1hwzb2_d4fpxb1__1				Proteobacteria		cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1hwzc1_d2hk8a2__1				Aquificae		cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1hwzc2_d4xgic1__1				Proteobacteria		nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]				nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1hwzd2_d2aw5c1__1		Metazoa		Chordata		cytosol [GO:0005829]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; manganese ion binding [GO:0030145]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxaloacetate decarboxylase activity [GO:0008948]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; nucleotide biosynthetic process [GO:0009165]; pyruvate metabolic process [GO:0006090]; regulation of lipid metabolic process [GO:0019216]; regulation of NADP metabolic process [GO:1902031]; response to carbohydrate [GO:0009743]; response to hormone [GO:0009725]		carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; nucleotide biosynthetic process [GO:0009165]; pyruvate metabolic process [GO:0006090]; regulation of lipid metabolic process [GO:0019216]; regulation of NADP metabolic process [GO:1902031]; response to carbohydrate [GO:0009743]; response to hormone [GO:0009725]		cytosol [GO:0005829]; mitochondrion [GO:0005739]		ADP binding [GO:0043531]; electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; manganese ion binding [GO:0030145]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxaloacetate decarboxylase activity [GO:0008948]
d1hwzd2_d3etdd1__1		Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1hx0a2_d3ndya___1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	carbohydrate catabolic process [GO:0016052]	cellulose catabolic process [GO:0030245]	extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]
d1hx1a1_d4fwka2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]; L-threonine catabolic process to propionate [GO:0070689]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	L-threonine catabolic process to propionate [GO:0070689]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]
d1hx1a2_d4h0pa1__1	Metazoa	Fungi	Chordata	Basidiomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]
d1hx3b1_d1ppvb1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]
d1hx8a1_d1oxza___1	Metazoa	Metazoa	Arthropoda	Chordata	cell [GO:0005623]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; 1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SNARE binding [GO:0000149]; chemical synaptic transmission [GO:0007268]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endocytosis [GO:0006897]; neuron-neuron synaptic transmission [GO:0007270]; phototaxis [GO:0042331]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle transport [GO:0048489]; vesicle budding from membrane [GO:0006900]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	chemical synaptic transmission [GO:0007268]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; endocytosis [GO:0006897]; neuron-neuron synaptic transmission [GO:0007270]; phototaxis [GO:0042331]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle transport [GO:0048489]; vesicle budding from membrane [GO:0006900]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	cell [GO:0005623]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SNARE binding [GO:0000149]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]
d1hxaa1_d4zh1c___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	cytoplasm [GO:0005737]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d1hxaa2_d4jzxa1__1	Viridiplantae		Streptophyta		cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	cytoplasm [GO:0005737]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]
d1hxf.1_d1u6qa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	serine-type endopeptidase activity [GO:0004252]
d1hxga1_d4gtmb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1hxha__d1hdca___1			Proteobacteria	Actinobacteria	dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; testosterone dehydrogenase [NAD(P)] activity [GO:0030283]; steroid metabolic process [GO:0008202]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; C21-steroid hormone metabolic process [GO:0008207]	steroid metabolic process [GO:0008202]	C21-steroid hormone metabolic process [GO:0008207]			dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; testosterone dehydrogenase [NAD(P)] activity [GO:0030283]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]
d1hxhc__d2jkvc1__1		Metazoa	Proteobacteria	Chordata	dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; testosterone dehydrogenase [NAD(P)] activity [GO:0030283]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate catabolic process [GO:0046177]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	steroid metabolic process [GO:0008202]	D-gluconate catabolic process [GO:0046177]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; testosterone dehydrogenase [NAD(P)] activity [GO:0030283]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]
d1hxja__d2bvtb2__1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	chloroplast [GO:0009507]		beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]
d1hxka2_d1l7ka1__1	Metazoa		Arthropoda	Firmicutes	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	galactose metabolic process [GO:0006012]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1hxka3_d1k1xb3__1	Metazoa		Arthropoda	Euryarchaeota	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]
d1hxma1_d5kd4c2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	transmembrane signaling receptor activity [GO:0004888]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hxmb1_d1f3dh2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	metal ion binding [GO:0046872]	adaptive immune response [GO:0002250]; immune response [GO:0006955]		integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]		transmembrane signaling receptor activity [GO:0004888]	metal ion binding [GO:0046872]
d1hxmb2_d2qqqc___1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	integral component of membrane [GO:0016021]	adaptive immune response [GO:0002250]; immune response [GO:0006955]		integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]	transmembrane signaling receptor activity [GO:0004888]	
d1hxmc1_d4dvrh1__1	Metazoa		Chordata		integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	transmembrane signaling receptor activity [GO:0004888]	structural molecule activity [GO:0005198]
d1hxmc2_d1ndma2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	transmembrane signaling receptor activity [GO:0004888]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1hxmd2_d5o4eb2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	adaptive immune response [GO:0002250]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	transmembrane signaling receptor activity [GO:0004888]	
d1hxme2_d1a4kb1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	transmembrane signaling receptor activity [GO:0004888]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1hxmf1_d1u8lb1__1	Metazoa		Chordata		integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]		adaptive immune response [GO:0002250]; immune response [GO:0006955]		integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]		transmembrane signaling receptor activity [GO:0004888]	
d1hxmf2_d4q2zb1__1	Metazoa		Chordata		integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]		adaptive immune response [GO:0002250]; immune response [GO:0006955]		integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]		transmembrane signaling receptor activity [GO:0004888]	
d1hxmg1_d4k07c___1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	transmembrane signaling receptor activity [GO:0004888]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d1hxmh1_d2bmkb1__1	Metazoa		Chordata		integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]		adaptive immune response [GO:0002250]; immune response [GO:0006955]		integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]		transmembrane signaling receptor activity [GO:0004888]	
d1hxna__d1qjsb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; heme binding [GO:0020037]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; extracellular region [GO:0005576]; heme binding [GO:0020037]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; extracellular region [GO:0005576]	cell [GO:0005623]; extracellular region [GO:0005576]	heme binding [GO:0020037]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]
d1hxna__d4fu4a2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; heme binding [GO:0020037]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular iron ion homeostasis [GO:0006879]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cell [GO:0005623]; extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	heme binding [GO:0020037]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1hxrb__d1fwqa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; guanyl-nucleotide exchange factor activity [GO:0005085]; zinc ion binding [GO:0008270]; post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	cytosol [GO:0005829]; membrane [GO:0016020]; guanyl-nucleotide exchange factor activity [GO:0005085]; zinc ion binding [GO:0008270]; membrane fusion [GO:0061025]; post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	membrane fusion [GO:0061025]; post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; membrane [GO:0016020]	guanyl-nucleotide exchange factor activity [GO:0005085]; zinc ion binding [GO:0008270]	guanyl-nucleotide exchange factor activity [GO:0005085]; zinc ion binding [GO:0008270]
d1hxs3__d1ar81___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1hxwb__d3q4ba___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d1hxya2_d4z7vc1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	nutrient reservoir activity [GO:0045735]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	nutrient reservoir activity [GO:0045735]
d1hxyb2_d2jcch2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hy3b__d2bwjf___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; estrone sulfotransferase activity [GO:0004304]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid binding [GO:0005496]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; estrogen catabolic process [GO:0006711]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; positive regulation of fat cell differentiation [GO:0045600]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; estrogen catabolic process [GO:0006711]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; positive regulation of fat cell differentiation [GO:0045600]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]	ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]	estrone sulfotransferase activity [GO:0004304]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid binding [GO:0005496]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d1hy8a__d5h9ga1__1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]; phosphopantetheine binding [GO:0031177]	lipid A biosynthetic process [GO:0009245]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]	acyl carrier activity [GO:0000036]; phosphopantetheine binding [GO:0031177]
d1hyea1_d1up7b1__1			Euryarchaeota	Thermotogae	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d1hygb1_d1euzc1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d1hylb__d1a0h.1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	collagen catabolic process [GO:0030574]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]
d1hynq__d1xiza1__1	Metazoa		Chordata	Proteobacteria	basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; Z disc [GO:0030018]; anion transmembrane transporter activity [GO:0008509]; anion:anion antiporter activity [GO:0015301]; ankyrin binding [GO:0030506]; bicarbonate transmembrane transporter activity [GO:0015106]; chloride transmembrane transporter activity [GO:0015108]; hemoglobin binding [GO:0030492]; inorganic anion exchanger activity [GO:0005452]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; anion transport [GO:0006820]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular ion homeostasis [GO:0006873]; chloride transport [GO:0006821]; erythrocyte development [GO:0048821]; glycolytic process [GO:0006096]; negative regulation of urine volume [GO:0035811]; pH elevation [GO:0045852]; plasma membrane phospholipid scrambling [GO:0017121]; protein localization to plasma membrane [GO:0072659]; regulation of intracellular pH [GO:0051453]	kinase activity [GO:0016301]	anion transport [GO:0006820]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular ion homeostasis [GO:0006873]; chloride transport [GO:0006821]; erythrocyte development [GO:0048821]; glycolytic process [GO:0006096]; negative regulation of urine volume [GO:0035811]; pH elevation [GO:0045852]; plasma membrane phospholipid scrambling [GO:0017121]; protein localization to plasma membrane [GO:0072659]; regulation of intracellular pH [GO:0051453]		basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; Z disc [GO:0030018]		anion:anion antiporter activity [GO:0015301]; anion transmembrane transporter activity [GO:0008509]; ankyrin binding [GO:0030506]; bicarbonate transmembrane transporter activity [GO:0015106]; chloride transmembrane transporter activity [GO:0015108]; hemoglobin binding [GO:0030492]; inorganic anion exchanger activity [GO:0005452]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]	kinase activity [GO:0016301]
d1hynr__d1j6ta___1	Metazoa		Chordata	Proteobacteria	basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; Z disc [GO:0030018]; anion transmembrane transporter activity [GO:0008509]; anion:anion antiporter activity [GO:0015301]; ankyrin binding [GO:0030506]; bicarbonate transmembrane transporter activity [GO:0015106]; chloride transmembrane transporter activity [GO:0015108]; hemoglobin binding [GO:0030492]; inorganic anion exchanger activity [GO:0005452]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; anion transport [GO:0006820]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular ion homeostasis [GO:0006873]; chloride transport [GO:0006821]; erythrocyte development [GO:0048821]; glycolytic process [GO:0006096]; negative regulation of urine volume [GO:0035811]; pH elevation [GO:0045852]; plasma membrane phospholipid scrambling [GO:0017121]; protein localization to plasma membrane [GO:0072659]; regulation of intracellular pH [GO:0051453]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity [GO:0022872]; protein-phosphocysteine-mannitol phosphotransferase system transporter activity [GO:0090565]; mannitol transport [GO:0015797]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	anion transport [GO:0006820]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular ion homeostasis [GO:0006873]; chloride transport [GO:0006821]; erythrocyte development [GO:0048821]; glycolytic process [GO:0006096]; negative regulation of urine volume [GO:0035811]; pH elevation [GO:0045852]; plasma membrane phospholipid scrambling [GO:0017121]; protein localization to plasma membrane [GO:0072659]; regulation of intracellular pH [GO:0051453]	mannitol transport [GO:0015797]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; Z disc [GO:0030018]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	anion:anion antiporter activity [GO:0015301]; anion transmembrane transporter activity [GO:0008509]; ankyrin binding [GO:0030506]; bicarbonate transmembrane transporter activity [GO:0015106]; chloride transmembrane transporter activity [GO:0015108]; hemoglobin binding [GO:0030492]; inorganic anion exchanger activity [GO:0005452]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity [GO:0022872]; protein-phosphocysteine-mannitol phosphotransferase system transporter activity [GO:0090565]
d1hypa__d1fk4a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta		lipid binding [GO:0008289]; lipid transport [GO:0006869]		lipid transport [GO:0006869]				lipid binding [GO:0008289]
d1hyrc1_d1mccb1__1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; MHC class I protein binding [GO:0042288]; MHC class Ib receptor activity [GO:0032394]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]		adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; MHC class Ib receptor activity [GO:0032394]; MHC class I protein binding [GO:0042288]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]	
d1hysd2_d5l9dl1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d1hyta__d3edha___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]; cartilage condensation [GO:0001502]; cell differentiation [GO:0030154]; extracellular matrix disassembly [GO:0022617]; high-density lipoprotein particle assembly [GO:0034380]; multicellular organism development [GO:0007275]; ossification [GO:0001503]; positive regulation of cartilage development [GO:0061036]; proteolysis [GO:0006508]; skeletal system development [GO:0001501]		cartilage condensation [GO:0001502]; cell differentiation [GO:0030154]; extracellular matrix disassembly [GO:0022617]; high-density lipoprotein particle assembly [GO:0034380]; multicellular organism development [GO:0007275]; ossification [GO:0001503]; positive regulation of cartilage development [GO:0061036]; proteolysis [GO:0006508]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; vesicle [GO:0031982]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	calcium ion binding [GO:0005509]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]
d1hyua3_d4zb6c1__1		Fungi	Proteobacteria	Basidiomycota	cell [GO:0005623]; alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]		cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]		cell [GO:0005623]		alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]	
d1hyxl3_d5ujta2__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]		
d1hyyl4_d2f53e1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]		
d1hyyl4_d3eyoc1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1hz6c__d1kh0b___1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]			cell wall [GO:0005618]; extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1hzda__d1tyfj___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1hzde__d1yg8i___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1hzdf__d3pgqc1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d1hzeb__d1frqa1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; riboflavin synthase activity [GO:0004746]; riboflavin biosynthetic process [GO:0009231]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	riboflavin biosynthetic process [GO:0009231]	photosynthesis [GO:0015979]	cytosol [GO:0005829]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	riboflavin synthase activity [GO:0004746]	ferredoxin-NADP+ reductase activity [GO:0004324]
d1hzhh2_d3mcg11__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]
d1hzhh3_d4h0ia1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1hzhk3_d1pkqa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	signaling receptor binding [GO:0005102]
d1hzhk3_d3mrhb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hzhk4_d5w1we2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1hzhl1_d4kmtl2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1hzhl2_d1xgta1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1hzhm1_d2feeo2__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1hzia__d2q98a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]; activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]	hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]
d1hzja__d2irwa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytosol [GO:0005829]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d1hzja__d4fj0b___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]		cytosol [GO:0005829]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1hzpb1_d2vu2b1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1hzpb2_d1u0va2__1		Viridiplantae	Actinobacteria	Streptophyta	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	naringenin-chalcone synthase activity [GO:0016210]
d1hzpb2_d4japb2__1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	polyketide synthase complex [GO:0034081]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	polyketide synthase complex [GO:0034081]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1hzwa__d3dg8c___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dihydrofolate reductase activity [GO:0004146]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]		cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; thymidylate synthase activity [GO:0004799]
d1i00b__d3kjra2__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]		cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]
d1i03b__d4qrna1__1				Proteobacteria		carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]						carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1i08a2_d2rcvb2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1i08b1_d1en4a1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1i08b1_d4yioa1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1i08d2_d3esfc2__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1i0ab__d3ocea1__1	Metazoa		Chordata	Proteobacteria	structural constituent of eye lens [GO:0005212]; arginine biosynthetic process via ornithine [GO:0042450]	aspartate ammonia-lyase activity [GO:0008797]; tricarboxylic acid cycle [GO:0006099]	arginine biosynthetic process via ornithine [GO:0042450]	tricarboxylic acid cycle [GO:0006099]			structural constituent of eye lens [GO:0005212]	aspartate ammonia-lyase activity [GO:0008797]
d1i0ac__d1u15b___1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; arginine biosynthetic process via ornithine [GO:0042450]	catalytic activity [GO:0003824]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process via ornithine [GO:0042450]	arginine biosynthetic process via ornithine [GO:0042450]	arginine biosynthetic process via ornithine [GO:0042450]			structural constituent of eye lens [GO:0005212]	catalytic activity [GO:0003824]; structural constituent of eye lens [GO:0005212]
d1i0ac__d3rrpa___1	Metazoa		Chordata	Actinobacteria	structural constituent of eye lens [GO:0005212]; arginine biosynthetic process via ornithine [GO:0042450]	tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	arginine biosynthetic process via ornithine [GO:0042450]	fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle enzyme complex [GO:0045239]	structural constituent of eye lens [GO:0005212]	fumarate hydratase activity [GO:0004333]
d1i0ba__d3be7a2__1			Proteobacteria		plasma membrane [GO:0005886]; aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]; catabolic process [GO:0009056]		catabolic process [GO:0009056]		plasma membrane [GO:0005886]		aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]	
d1i0da__d1k70a2__1			Proteobacteria	Proteobacteria	plasma membrane [GO:0005886]; aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]; catabolic process [GO:0009056]	cytosol [GO:0005829]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; isoguanine deaminase activity [GO:0035888]; zinc ion binding [GO:0008270]; cytosine catabolic process [GO:0006209]	catabolic process [GO:0009056]	cytosine catabolic process [GO:0006209]	plasma membrane [GO:0005886]	cytosol [GO:0005829]	aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; isoguanine deaminase activity [GO:0035888]; zinc ion binding [GO:0008270]
d1i0eb1_d3l2fk1__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		cytosol [GO:0005829]; extracellular space [GO:0005615]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]	
d1i0ec1_d4z9md1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; phosphocreatine biosynthetic process [GO:0046314]	creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; phosphocreatine biosynthetic process [GO:0046314]	cytosol [GO:0005829]; extracellular space [GO:0005615]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d1i0ec1_d5j9aa1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	cytosol [GO:0005829]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]	arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d1i0ed1_d3l2gr1__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		cytosol [GO:0005829]; extracellular space [GO:0005615]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]	
d1i0hb1_d2cw3b1__1			Proteobacteria	Perkinsozoa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	integral component of membrane [GO:0016021]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1i0hb2_d3ak1a2__1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1i0la__d5mp7b1__1				Actinobacteria	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]
d1i0ra__d1flmb___1			Euryarchaeota	Proteobacteria	FMN binding [GO:0010181]; oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [GO:0016723]; protein homodimerization activity [GO:0042803]	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	FMN binding [GO:0010181]; oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [GO:0016723]; protein homodimerization activity [GO:0042803]	cofactor binding [GO:0048037]
d1i0wa__d3sbpa2__1				Proteobacteria		membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]		copper ion import [GO:0015677]; denitrification pathway [GO:0019333]		membrane [GO:0016020]; periplasmic space [GO:0042597]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d1i0xd__d1fysa___1	Fungi	Fungi	Ascomycota	Ascomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1i0za1_d1w4za___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; identical protein binding [GO:0042802]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; pyruvate metabolic process [GO:0006090]	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]	carbohydrate metabolic process [GO:0005975]; pyruvate metabolic process [GO:0006090]	antibiotic biosynthetic process [GO:0017000]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]		identical protein binding [GO:0042802]; L-lactate dehydrogenase activity [GO:0004459]	oxidoreductase activity [GO:0016491]
d1i10b2_d1oc4a2__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; oxidoreductase activity [GO:0016491]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]		cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; oxidoreductase activity [GO:0016491]
d1i10c1_d1z7ef2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]		cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]
d1i10c2_d1guzb2__1	Metazoa		Chordata	Chlorobi	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]		cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-malate dehydrogenase activity [GO:0030060]
d1i10d2_d1b8va2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]		cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-malate dehydrogenase activity [GO:0030060]
d1i10d2_d4rosa2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]		cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-malate dehydrogenase activity [GO:0030060]
d1i10e1_d1b8pa1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]		cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-malate dehydrogenase activity [GO:0030060]
d1i10e1_d2qiod___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]		cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d1i10f1_d4i9ud1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]
d1i10f2_d2ldxd2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]; L-lactate dehydrogenase activity [GO:0004459]; ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]
d1i19b2_d1v97a6__1		Metazoa	Actinobacteria	Chordata	FAD binding [GO:0071949]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [GO:0016899]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	FAD binding [GO:0071949]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [GO:0016899]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1i1ca1_d2clvh1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1i1cb1_d1w72l1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1i1cb2_d2q8bl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1i1fa1_d2r0zl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1i1fe2_d4zsoa2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1i1ip__d3fv4a___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; oligopeptidase activity [GO:0070012]; peptide metabolic process [GO:0006518]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	peptide metabolic process [GO:0006518]; proteolysis [GO:0006508]		cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; oligopeptidase activity [GO:0070012]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1i1oa__d4fgla___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1i1ra2_d1uj3c1__1	Metazoa	Metazoa	Chordata	Chordata	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]	ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]	cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]
d1i1ra2_d2doca1__1	Metazoa	Metazoa	Chordata	Chordata	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	axon [GO:0030424]; integral component of membrane [GO:0016021]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; axonal fasciculation [GO:0007413]; neuron cell-cell adhesion [GO:0007158]; sensory perception of smell [GO:0007608]	ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	axonal fasciculation [GO:0007413]; neuron cell-cell adhesion [GO:0007158]; sensory perception of smell [GO:0007608]	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	axon [GO:0030424]; integral component of membrane [GO:0016021]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]	ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]
d1i1rb__d2erjd___1	Metazoa	Metazoa	Chordata	Chordata	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]; interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]	ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]	interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]
d1i1wa__d3mmwb___1	Fungi		Ascomycota	Thermotogae	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	xylan catabolic process [GO:0045493]	cellular glucan metabolic process [GO:0006073]		extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1i1wa__d3vd3b3__1	Fungi		Ascomycota	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	endo-1,4-beta-xylanase activity [GO:0031176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1i1ya2_d4ozfb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1i1ye2_d2ih3b1__1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	voltage-gated potassium channel complex [GO:0008076]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1i1za__d1nf5a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1i22a__d4j1aa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1i22b__d2pc2a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1i22c__d2nzba___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]		antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1i22d__d1jn8c___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]		antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1i24a1_d2hsda___1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast [GO:0009507]; plasma membrane [GO:0005886]; coenzyme binding [GO:0050662]; sulfotransferase activity [GO:0008146]; UDPsulfoquinovose synthase activity [GO:0046507]; zinc ion binding [GO:0008270]; cellular response to phosphate starvation [GO:0016036]; glycolipid biosynthetic process [GO:0009247]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; C21-steroid hormone metabolic process [GO:0008207]	cellular response to phosphate starvation [GO:0016036]; glycolipid biosynthetic process [GO:0009247]	C21-steroid hormone metabolic process [GO:0008207]	chloroplast [GO:0009507]; plasma membrane [GO:0005886]		coenzyme binding [GO:0050662]; sulfotransferase activity [GO:0008146]; UDPsulfoquinovose synthase activity [GO:0046507]; zinc ion binding [GO:0008270]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]
d1i2db1_d1m8pa1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1i2db1_d4mafb1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	nucleotide binding [GO:0000166]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]		adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	nucleotide binding [GO:0000166]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1i2dc2_d4nauc___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1i2dc3_d1g8ha3__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1i2na__d1ok4f___1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; membrane [GO:0016020]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	glycolytic process [GO:0006096]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	fructose-bisphosphate aldolase activity [GO:0004332]
d1i2na__d3mmta1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	glycolytic process [GO:0006096]	cytosol [GO:0005829]; membrane [GO:0016020]		sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	fructose-bisphosphate aldolase activity [GO:0004332]
d1i2ob__d1wx0f___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; membrane [GO:0016020]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d1i2ob__d4rz4e1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	fructose metabolic process [GO:0006000]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	fructose 6-phosphate aldolase activity [GO:0097023]
d1i2pb__d1yxda___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]
d1i2qb__d1xxxf___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1i2zb__d5jlab___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	nucleotide binding [GO:0000166]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]; membrane [GO:0016020]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]
d1i32a2_d1diha2__1				Proteobacteria	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; cellular amino acid biosynthetic process [GO:0008652]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cellular amino acid biosynthetic process [GO:0008652]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycosome [GO:0020015]	cytosol [GO:0005829]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]
d1i32e2_d1crwr2__1		Metazoa		Arthropoda	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glycosome [GO:0020015]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1i33c2_d1p1jb2__1		Fungi		Ascomycota	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; inositol-3-phosphate synthase activity [GO:0004512]; inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	glycosome [GO:0020015]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	inositol-3-phosphate synthase activity [GO:0004512]
d1i36a2_d6ldha1__1		Metazoa	Euryarchaeota	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		cytoplasm [GO:0005737]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	L-lactate dehydrogenase activity [GO:0004459]
d1i3aa__d2lsna1__1			Euryarchaeota		cytoplasm [GO:0005737]; manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; RNA catabolic process [GO:0006401]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; virion [GO:0019012]; aspartic-type endopeptidase activity [GO:0004190]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	RNA catabolic process [GO:0006401]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; virion [GO:0019012]	manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1i3db__d5b13a___1	Metazoa		Chordata	Rhodophyta	cytosol [GO:0005829]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytosol [GO:0005829]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1i3eb__d1yhud___1	Metazoa	Metazoa	Chordata	Annelida	cytosol [GO:0005829]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cytosol [GO:0005829]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1i3gh1_d3kpob1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1i3gl__d5gryg1__1												
d1i3ia__d1r4ya___1	Fungi	Fungi	Ascomycota	Ascomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]; rRNA endonuclease activity [GO:0033902]; negative regulation of translation [GO:0017148]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]		negative regulation of translation [GO:0017148]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]; rRNA endonuclease activity [GO:0033902]
d1i3ma__d2x6ti___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]	cytosol [GO:0005829]; membrane [GO:0016020]; ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]
d1i3mb__d1q7ba___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]	cytosol [GO:0005829]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]	galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]	biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d1i3na__d1nr7d1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytosol [GO:0005829]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1i3ra2_d4k71e1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1i3rd2_d4l3ce1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1i3rf1_d2dqdh1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1i3rg1_d5nmda1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]		integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]			
d1i3rh1_d5dhxl2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	host cell cytoplasm [GO:0030430]; host cell nucleolus [GO:0044196]; DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]; mRNA transport [GO:0051028]; viral process [GO:0016032]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	mRNA transport [GO:0051028]; viral process [GO:0016032]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	host cell cytoplasm [GO:0030430]; host cell nucleolus [GO:0044196]		DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]
d1i3ua__d2ny5l1__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1i3ua__d5durl2__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d1i40a__d4z74e1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1i41c__d4gsab___1	Viridiplantae		Streptophyta	Cyanobacteria	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	transsulfuration [GO:0019346]	chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]		cytoplasm [GO:0005737]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1i41e__d4eb5a___1	Viridiplantae		Streptophyta	Euryarchaeota	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; iron-sulfur cluster assembly [GO:0016226]	transsulfuration [GO:0019346]	iron-sulfur cluster assembly [GO:0016226]			catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]
d1i41h__d2biga___1	Viridiplantae		Streptophyta	Firmicutes	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]	transsulfuration [GO:0019346]	L-serine biosynthetic process [GO:0006564]		cytoplasm [GO:0005737]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]
d1i41j__d4w5kb___1	Viridiplantae		Streptophyta		catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear lumen [GO:0031981]; L-alanine:2-oxoglutarate aminotransferase activity [GO:0004021]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]; L-methionine salvage from methylthioadenosine [GO:0019509]	transsulfuration [GO:0019346]	biosynthetic process [GO:0009058]; L-methionine salvage from methylthioadenosine [GO:0019509]		ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear lumen [GO:0031981]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	L-alanine:2-oxoglutarate aminotransferase activity [GO:0004021]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]
d1i43a__d1d2fa___1	Viridiplantae		Streptophyta	Proteobacteria	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; methionine biosynthetic process [GO:0009086]; negative regulation of DNA-binding transcription factor activity [GO:0043433]	transsulfuration [GO:0019346]	methionine biosynthetic process [GO:0009086]; negative regulation of DNA-binding transcription factor activity [GO:0043433]			catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]
d1i43d__d5ft4b___1	Viridiplantae		Streptophyta	Proteobacteria	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]; selenocysteine lyase activity [GO:0009000]; sulfurtransferase activity [GO:0016783]; iron-sulfur cluster assembly [GO:0016226]; sulfur amino acid metabolic process [GO:0000096]	transsulfuration [GO:0019346]	iron-sulfur cluster assembly [GO:0016226]; sulfur amino acid metabolic process [GO:0000096]			catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]; selenocysteine lyase activity [GO:0009000]; sulfurtransferase activity [GO:0016783]
d1i48c__d3aeod___1	Viridiplantae		Streptophyta		catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	transsulfuration [GO:0019346]	transsulfuration [GO:0019346]			catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d1i48g__d2vlfa___1	Viridiplantae		Streptophyta	Proteobacteria	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	transsulfuration [GO:0019346]	tyrosine metabolic process [GO:0006570]			catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	tyrosine phenol-lyase activity [GO:0050371]
d1i48h__d3ei6a1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	transsulfuration [GO:0019346]	lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1i48h__d4kyoa___1	Viridiplantae	Metazoa	Streptophyta	Chordata	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]; cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]	transsulfuration [GO:0019346]	cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]		cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]
d1i48j__d1b5ob___1	Viridiplantae		Streptophyta	Deinococcus-Thermus	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	transsulfuration [GO:0019346]	biosynthetic process [GO:0009058]		cytoplasm [GO:0005737]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]
d1i48j__d5f9sa___1	Viridiplantae	Metazoa	Streptophyta	Chordata	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]; cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]	transsulfuration [GO:0019346]	cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]		cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]
d1i49b__d4i1qb___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; trans-Golgi network membrane [GO:0032588]; cadherin binding [GO:0045296]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phospholipid binding [GO:0005543]; protein domain specific binding [GO:0019904]; Rac GTPase binding [GO:0048365]; actin cytoskeleton organization [GO:0030036]; autophagy [GO:0006914]; intracellular protein transport [GO:0006886]; lamellipodium assembly [GO:0030032]; ruffle organization [GO:0031529]; small GTPase mediated signal transduction [GO:0007264]	cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; podosome [GO:0002102]; secretory granule lumen [GO:0034774]; phospholipid binding [GO:0005543]; cell chemotaxis [GO:0060326]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; plasma membrane tubulation [GO:0097320]; podosome assembly [GO:0071800]	actin cytoskeleton organization [GO:0030036]; autophagy [GO:0006914]; intracellular protein transport [GO:0006886]; lamellipodium assembly [GO:0030032]; ruffle organization [GO:0031529]; small GTPase mediated signal transduction [GO:0007264]	cell chemotaxis [GO:0060326]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; plasma membrane tubulation [GO:0097320]; podosome assembly [GO:0071800]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; trans-Golgi network membrane [GO:0032588]	cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; podosome [GO:0002102]; secretory granule lumen [GO:0034774]	cadherin binding [GO:0045296]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phospholipid binding [GO:0005543]; protein domain specific binding [GO:0019904]; Rac GTPase binding [GO:0048365]	phospholipid binding [GO:0005543]
d1i4fa1_d4x4xa___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1i4fa2_d4z77d1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1i4fb2_d1hxma2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	transmembrane signaling receptor activity [GO:0004888]
d1i4fb2_d3cfki1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1i4hb1_d1fnva1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1i4jb__d2gycq1__1			Deinococcus-Thermus		large ribosomal subunit [GO:0015934]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		large ribosomal subunit [GO:0015934]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1i4k2__d1h64v___1			Euryarchaeota	Euryarchaeota								
d1i4kd__d1vu3a___1			Euryarchaeota									
d1i4ke__d1lojk1__1			Euryarchaeota	Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]		
d1i4ki__d1mgqe___1			Euryarchaeota	Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]		
d1i4kl__d3swnt___1		Fungi	Euryarchaeota	Ascomycota		Lsm2-8 complex [GO:0120115]; nucleolus [GO:0005730]; nucleus [GO:0005634]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; maturation of SSU-rRNA [GO:0030490]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; telomerase holoenzyme complex assembly [GO:1905323]; tRNA processing [GO:0008033]		maturation of SSU-rRNA [GO:0030490]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; telomerase holoenzyme complex assembly [GO:1905323]; tRNA processing [GO:0008033]		Lsm2-8 complex [GO:0120115]; nucleolus [GO:0005730]; nucleus [GO:0005634]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]		poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]
d1i4km__d1i81c___1			Euryarchaeota	Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]		
d1i4ku__d1i8fc1__1			Euryarchaeota	Crenarchaeota								
d1i4kw__d1vu2c___1			Euryarchaeota									
d1i4kx__d1vu3g___1			Euryarchaeota									
d1i4nb__d1q6rb___1			Thermotogae	Proteobacteria	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]			indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1i4pa2_d1eu3b2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]
d1i4ra2_d4o1nc2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; peptidase activity [GO:0008233]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	peptidase activity [GO:0008233]
d1i4ua__d2dm5a___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular space [GO:0005615]; pigment binding [GO:0031409]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]		aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	pigment binding [GO:0031409]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]
d1i4ub__d1u18a___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular space [GO:0005615]; pigment binding [GO:0031409]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]		vasodilation [GO:0042311]	extracellular space [GO:0005615]	extracellular region [GO:0005576]	pigment binding [GO:0031409]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]
d1i4wa__d1yuba___1	Fungi		Ascomycota	Firmicutes	mitochondrial DNA-directed RNA polymerase complex [GO:0034245]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; DNA binding [GO:0003677]; methyltransferase activity [GO:0008168]; mitochondrial sequence-specific DNA-binding transcription factor activity [GO:0034246]; RNA binding [GO:0003723]; transcription initiation from mitochondrial promoter [GO:0006391]	23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity [GO:0052910]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]; response to antibiotic [GO:0046677]	transcription initiation from mitochondrial promoter [GO:0006391]	response to antibiotic [GO:0046677]	mitochondrial DNA-directed RNA polymerase complex [GO:0034245]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		DNA binding [GO:0003677]; methyltransferase activity [GO:0008168]; mitochondrial sequence-specific DNA-binding transcription factor activity [GO:0034246]; RNA binding [GO:0003723]	23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity [GO:0052910]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]
d1i4yh__d1i4zh___1	Metazoa	Metazoa	Annelida	Annelida	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]					iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]
d1i53b__d4gp5b2__1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1i54a__d2a06d1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1i55b__d1wved___1	Metazoa		Chordata	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]			mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]
d1i5ea__d1ecfa1__1			Firmicutes	Proteobacteria	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]
d1i5ia1_d1wkta___1	Metazoa	Fungi	Chordata	Ascomycota	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; cell death [GO:0008219]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	cell death [GO:0008219]		extracellular region [GO:0005576]	structural constituent of eye lens [GO:0005212]	toxin activity [GO:0090729]
d1i5ia2_d2v2ub2__1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; camera-type eye development [GO:0043010]; eye development [GO:0001654]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	camera-type eye development [GO:0043010]; eye development [GO:0001654]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d1i5lf__d1lnxf1__1			Euryarchaeota	Crenarchaeota								
d1i5lh__d1n9re___1		Fungi	Euryarchaeota	Ascomycota		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]
d1i5lm__d5mknp___1			Euryarchaeota	Euryarchaeota								
d1i5ra__d5itva1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]; estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]	estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	antibiotic biosynthetic process [GO:0017000]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]	oxidoreductase activity [GO:0016491]
d1i5za2_d3ogja___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]
d1i6aa__d4i9db___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; cellular response to DNA damage stimulus [GO:0006974]; regulation of DNA-templated transcription, initiation [GO:2000142]; response to nitrosative stress [GO:0051409]; response to oxidative stress [GO:0006979]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	cellular response to DNA damage stimulus [GO:0006974]; regulation of DNA-templated transcription, initiation [GO:2000142]; response to nitrosative stress [GO:0051409]; response to oxidative stress [GO:0006979]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	cytosol [GO:0005829]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]
d1i6da__d4eifa___1			Proteobacteria	Cyanobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1i6ma__d1jedb2__1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	tryptophanyl-tRNA aminoacylation [GO:0006436]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1i6pa__d2a8cc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbon utilization [GO:0015976]	carbon utilization [GO:0015976]	cytosol [GO:0005829]		carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1i6sa__d1lzga___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1i6va2_d1i3qc2__1		Fungi	Deinococcus-Thermus	Ascomycota	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	transcription, DNA-templated [GO:0006351]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]		cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]
d1i6wb__d5tnjd___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	hydrolase activity [GO:0016787]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]		lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	hydrolase activity [GO:0016787]
d1i6xb2_d4z07c2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]
d1i73a__d2jsda___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; amelogenesis [GO:0097186]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of enamel mineralization [GO:0070173]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	amelogenesis [GO:0097186]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of enamel mineralization [GO:0070173]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1i73a__d3flfa___1	Metazoa		Chordata	Firmicutes	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]		collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1i75a2_d2j71a1__1			Firmicutes	Thermotogae	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]
d1i75b2_d4jcla4__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1i76a__d1fjoa___1	Metazoa		Chordata	Firmicutes	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]		collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1i7hb__d4ytnf1__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cytosol [GO:0005829]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; iron-sulfur cluster assembly [GO:0016226]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	iron-sulfur cluster assembly [GO:0016226]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d1i7hc__d3amza1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; iron-sulfur cluster assembly [GO:0016226]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	iron-sulfur cluster assembly [GO:0016226]	xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1i7oc1_d5ti1c2__1			Proteobacteria	Proteobacteria	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity [GO:0008704]; 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity [GO:0018800]; metal ion binding [GO:0046872]; 4-hydroxyphenylacetate catabolic process [GO:1901023]	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]; aromatic amino acid family metabolic process [GO:0009072]	4-hydroxyphenylacetate catabolic process [GO:1901023]	aromatic amino acid family metabolic process [GO:0009072]			5-carboxymethyl-2-hydroxymuconate delta-isomerase activity [GO:0008704]; 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity [GO:0018800]; metal ion binding [GO:0046872]	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]
d1i7od1_d1qqjb2__1		Metazoa	Proteobacteria	Chordata	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity [GO:0008704]; 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity [GO:0018800]; metal ion binding [GO:0046872]; 4-hydroxyphenylacetate catabolic process [GO:1901023]	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]; arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	4-hydroxyphenylacetate catabolic process [GO:1901023]	arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]			5-carboxymethyl-2-hydroxymuconate delta-isomerase activity [GO:0008704]; 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity [GO:0018800]; metal ion binding [GO:0046872]	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]
d1i7qb__d1qdlb___1			Proteobacteria	Crenarchaeota	anthranilate synthase activity [GO:0004049]; glutamine metabolic process [GO:0006541]; tryptophan biosynthetic process [GO:0000162]	anthranilate synthase activity [GO:0004049]; glutamine metabolic process [GO:0006541]; tryptophan biosynthetic process [GO:0000162]	glutamine metabolic process [GO:0006541]; tryptophan biosynthetic process [GO:0000162]	glutamine metabolic process [GO:0006541]; tryptophan biosynthetic process [GO:0000162]			anthranilate synthase activity [GO:0004049]	anthranilate synthase activity [GO:0004049]
d1i7sd__d3b38a1__1		Metazoa	Proteobacteria	Chordata	anthranilate synthase activity [GO:0004049]; glutamine metabolic process [GO:0006541]; tryptophan biosynthetic process [GO:0000162]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	glutamine metabolic process [GO:0006541]; tryptophan biosynthetic process [GO:0000162]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]		axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]	anthranilate synthase activity [GO:0004049]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]
d1i7ta1_d5f6hj1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1i7te2_d3cxhj___1	Metazoa	Fungi	Chordata	Ascomycota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1i7ua1_d2virb2__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]
d1i7ua1_d5e99l1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1i7ub2_d1mcha1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1i7ud1_d4rmua___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1i7ue2_d4fq1l1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1i7zc1_d4p2ci___1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1i7zd1_d1q9ta4__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1i80a__d1ecpe___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; purine-nucleoside phosphorylase activity [GO:0004731]; deoxyguanosine catabolic process [GO:0006161]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	deoxyguanosine catabolic process [GO:0006161]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	purine-nucleoside phosphorylase activity [GO:0004731]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]
d1i80b__d1ov6c___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; purine-nucleoside phosphorylase activity [GO:0004731]; deoxyguanosine catabolic process [GO:0006161]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	deoxyguanosine catabolic process [GO:0006161]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	purine-nucleoside phosphorylase activity [GO:0004731]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]
d1i81f__d4f77y___1			Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]			
d1i82a__d1d7cb___1		Fungi	Thermotogae	Basidiomycota	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]
d1i85a__d2a6jb3__1	Metazoa		Chordata		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]			
d1i85c__d1lgva1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]			
d1i89a2_d1fj4d1__1	Viridiplantae		Streptophyta	Proteobacteria	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	naringenin-chalcone synthase activity [GO:0016210]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1i8db1_d2bgia1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; riboflavin synthase activity [GO:0004746]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	riboflavin biosynthetic process [GO:0009231]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	riboflavin synthase activity [GO:0004746]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1i8ia__d4yhll2__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1i8ib__d1g6rc1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1i8ib__d4evnj1__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1i8ja__d5hmsb___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; catalytic activity [GO:0003824]; identical protein binding [GO:0042802]; porphobilinogen synthase activity [GO:0004655]; proteasome core complex binding [GO:1904854]; zinc ion binding [GO:0008270]; cellular response to interleukin-4 [GO:0071353]; cellular response to lead ion [GO:0071284]; heme biosynthetic process [GO:0006783]; negative regulation of proteasomal protein catabolic process [GO:1901799]; neutrophil degranulation [GO:0043312]; protein homooligomerization [GO:0051260]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to activity [GO:0014823]; response to aluminum ion [GO:0010044]; response to amino acid [GO:0043200]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to cobalt ion [GO:0032025]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542]; response to glucocorticoid [GO:0051384]; response to herbicide [GO:0009635]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to iron ion [GO:0010039]; response to lipopolysaccharide [GO:0032496]; response to mercury ion [GO:0046689]; response to methylmercury [GO:0051597]; response to oxidative stress [GO:0006979]; response to platinum ion [GO:0070541]; response to selenium ion [GO:0010269]; response to vitamin B1 [GO:0010266]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cellular response to interleukin-4 [GO:0071353]; cellular response to lead ion [GO:0071284]; heme biosynthetic process [GO:0006783]; negative regulation of proteasomal protein catabolic process [GO:1901799]; neutrophil degranulation [GO:0043312]; protein homooligomerization [GO:0051260]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to activity [GO:0014823]; response to aluminum ion [GO:0010044]; response to amino acid [GO:0043200]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to cobalt ion [GO:0032025]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542]; response to glucocorticoid [GO:0051384]; response to herbicide [GO:0009635]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to iron ion [GO:0010039]; response to lipopolysaccharide [GO:0032496]; response to mercury ion [GO:0046689]; response to methylmercury [GO:0051597]; response to oxidative stress [GO:0006979]; response to platinum ion [GO:0070541]; response to selenium ion [GO:0010269]; response to vitamin B1 [GO:0010266]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	magnesium ion binding [GO:0000287]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]	catalytic activity [GO:0003824]; identical protein binding [GO:0042802]; porphobilinogen synthase activity [GO:0004655]; proteasome core complex binding [GO:1904854]; zinc ion binding [GO:0008270]
d1i8kb__d1lo5b1__1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]
d1i8la2_d2z8wd1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]			
d1i8lc__d1c16g1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1i8ma1_d3u46b1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1i8ma2_d4rirl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1i8mh1_d5gs1n___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1i8oa__d1m6zd1__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	photosynthesis [GO:0015979]			periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1i8pd__d1qksb1__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	photosynthesis [GO:0015979]			periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1i8qa4_d1egua3__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d1i8qa4_d1ns8b1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	carbohydrate metabolic process [GO:0005975]	galactose metabolic process [GO:0006012]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1i8ua__d4qi3a1__1		Fungi	Thermotogae	Ascomycota	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	cellulose binding [GO:0030248]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]
d1i8va__d1ygwa___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1i8va__d4j5gb___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1i8vb__d1brhb___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1i8vb__d1rcla___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1i92a1_d2yuba1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]; beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; actin cytoskeleton organization [GO:0030036]; cornea development in camera-type eye [GO:0061303]; head development [GO:0060322]; protein phosphorylation [GO:0006468]; spermatogenesis [GO:0007283]	actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein-containing complex assembly [GO:0065003]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton organization [GO:0030036]; cornea development in camera-type eye [GO:0061303]; head development [GO:0060322]; protein phosphorylation [GO:0006468]; spermatogenesis [GO:0007283]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]	cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; nucleus [GO:0005634]	beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d1i94e1_d1oyrb1__1			Deinococcus-Thermus	Firmicutes	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	translation [GO:0006412]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d1i94g__d2qalg1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1i94i__d1udoa1__1			Deinococcus-Thermus	Aquificae	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	translation [GO:0006412]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d1i94l__d4ycwe1__1		Metazoa	Deinococcus-Thermus	Chordata	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]; activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	translation [GO:0006412]	activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	ribosome [GO:0005840]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]
d1i94o__d3df1o1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1i94t__d1hnwt___1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1i95b__d2qbhb1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1i95g__d2qbbg1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1i95i__d1mu5a2__1			Deinococcus-Thermus	Crenarchaeota	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	translation [GO:0006412]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]
d1i95j__d1vs5j1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1i95l__d4pg3b1__1			Deinococcus-Thermus	Apicomplexa	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytosol [GO:0005829]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; tRNA binding [GO:0000049]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; lysyl-tRNA aminoacylation [GO:0006430]	translation [GO:0006412]	diadenosine tetraphosphate biosynthetic process [GO:0015966]; lysyl-tRNA aminoacylation [GO:0006430]	ribosome [GO:0005840]	cytosol [GO:0005829]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; tRNA binding [GO:0000049]
d1i95o__d3df3o1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1i96i__d3wu4a___1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1i96l__d2qp0l1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1i96t__d1fjgt___1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1i97d__d2z4kd1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1i97k__d2hsta___1		Metazoa	Deinococcus-Thermus	Chordata	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; translation release factor complex [GO:0018444]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; translation release factor activity [GO:0003747]; translation release factor activity, codon specific [GO:0016149]; translation termination factor activity [GO:0008079]; cytoplasmic translational termination [GO:0002184]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein methylation [GO:0006479]; regulation of translational termination [GO:0006449]	translation [GO:0006412]	cytoplasmic translational termination [GO:0002184]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein methylation [GO:0006479]; regulation of translational termination [GO:0006449]	ribosome [GO:0005840]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; translation release factor complex [GO:0018444]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	ribosome binding [GO:0043022]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; translation release factor activity [GO:0003747]; translation release factor activity, codon specific [GO:0016149]; translation termination factor activity [GO:0008079]
d1i97k__d3df3k1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1i99e__d3s9aa___1		Metazoa		Chordata		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]
d1i9be1_d4uxua___1	Metazoa	Metazoa	Mollusca	Chordata	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	acetylcholine-gated channel complex [GO:0005892]; cell [GO:0005623]; cell junction [GO:0030054]; cholinergic synapse [GO:0098981]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic specialization membrane [GO:0099060]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; synapse [GO:0045202]; acetylcholine-gated cation-selective channel activity [GO:0022848]; calcium channel activity [GO:0005262]; transmembrane signaling receptor activity [GO:0004888]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; inner ear morphogenesis [GO:0042472]; ion transmembrane transport [GO:0034220]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; nervous system process [GO:0050877]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]		chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; inner ear morphogenesis [GO:0042472]; ion transmembrane transport [GO:0034220]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; nervous system process [GO:0050877]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	acetylcholine-gated channel complex [GO:0005892]; cell [GO:0005623]; cell junction [GO:0030054]; cholinergic synapse [GO:0098981]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic specialization membrane [GO:0099060]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	acetylcholine-gated cation-selective channel activity [GO:0022848]; calcium channel activity [GO:0005262]; transmembrane signaling receptor activity [GO:0004888]
d1i9da__d3vwxb1__1		Metazoa	Proteobacteria	Arthropoda	arsenate reductase (glutaredoxin) activity [GO:0008794]; response to arsenic-containing substance [GO:0046685]	glutathione transferase activity [GO:0004364]	response to arsenic-containing substance [GO:0046685]				arsenate reductase (glutaredoxin) activity [GO:0008794]	glutathione transferase activity [GO:0004364]
d1i9ha__d3szjb1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1i9ih2_d1hilb1__1	Metazoa		Chordata									
d1i9jh1_d1opgl1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1i9jh1_d3mzte___1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1i9jh2_d3q3gc2__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]
d1i9jl2_d1ikfl1__1	Metazoa		Chordata									
d1i9ma__d3p29a___1	Metazoa		Chordata		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	
d1i9oa__d5tv3e___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1i9rb__d4d7ya___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]; activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	climbing fiber [GO:0044301]; collagen trimer [GO:0005581]; cytoplasm [GO:0005737]; presynapse [GO:0098793]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; maintenance of synapse structure [GO:0099558]; motor learning [GO:0061743]; neuron remodeling [GO:0016322]	activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	maintenance of synapse structure [GO:0099558]; motor learning [GO:0061743]; neuron remodeling [GO:0016322]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	climbing fiber [GO:0044301]; collagen trimer [GO:0005581]; cytoplasm [GO:0005737]; presynapse [GO:0098793]; synaptic cleft [GO:0043083]	CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]	signaling receptor binding [GO:0005102]
d1i9rh2_d1q8ma1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]; activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]; acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]	activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]	scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]
d1i9rm2_d4od3l2__1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]; activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]	
d1i9rx1_d1gl4b___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]; activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; calcium ion binding [GO:0005509]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell death [GO:0060548]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; tissue development [GO:0009888]	activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiac muscle tissue development [GO:0048738]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; chondrocyte differentiation [GO:0002062]; embryonic skeletal system morphogenesis [GO:0048704]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of cell death [GO:0060548]; protein localization [GO:0008104]; receptor-mediated endocytosis [GO:0006898]; tissue development [GO:0009888]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]	CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]	calcium ion binding [GO:0005509]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]
d1i9ry1_d1mckb1__1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]; activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]	
d1i9ry2_d4kmtl1__1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]; activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]	
d1ia1b__d3hj3b1__1	Fungi		Ascomycota		dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	
d1ia2a__d3ghva___1	Fungi	Metazoa	Ascomycota	Chordata	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1ia2a__d5istx___1	Fungi		Ascomycota	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d1ia2b__d4elbd1__1	Fungi		Ascomycota	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1ia4a__d4elhd1__1	Fungi		Ascomycota	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1ia7a__d1g87a1__1			Firmicutes	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d1ia7a__d4wu0a___1			Firmicutes	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	catalytic activity [GO:0003824]	polysaccharide catabolic process [GO:0000272]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]
d1iaih2_d1yuha1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1iail2_d4rgng1__1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1iaim1_d2ckbl___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1iaim2_d3uzeb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1iaim2_d4zykb2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1iama1_d1jpsl1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]	cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]
d1iama2_d1j88e1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	Fc-epsilon receptor signaling pathway [GO:0038095]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]	IgE binding [GO:0019863]
d1iaob1_d1kn2h1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1iasa__d1finc___1	Metazoa	Metazoa	Chordata	Chordata	activin receptor complex [GO:0048179]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell surface [GO:0009986]; endosome [GO:0005768]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; activin binding [GO:0048185]; activin receptor activity, type I [GO:0016361]; ATP binding [GO:0005524]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity, type I [GO:0005025]; transforming growth factor beta-activated receptor activity [GO:0005024]; type II transforming growth factor beta receptor binding [GO:0005114]; activation of MAPKK activity [GO:0000186]; activin receptor signaling pathway [GO:0032924]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; epicardium morphogenesis [GO:1905223]; epithelial to mesenchymal transition [GO:0001837]; extracellular structure organization [GO:0043062]; germ cell migration [GO:0008354]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; protein deubiquitination [GO:0016579]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; regulation of transcription, DNA-templated [GO:0006355]; response to cholesterol [GO:0070723]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	activation of MAPKK activity [GO:0000186]; activin receptor signaling pathway [GO:0032924]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; epicardium morphogenesis [GO:1905223]; epithelial to mesenchymal transition [GO:0001837]; extracellular structure organization [GO:0043062]; germ cell migration [GO:0008354]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; protein deubiquitination [GO:0016579]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; regulation of transcription, DNA-templated [GO:0006355]; response to cholesterol [GO:0070723]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	activin receptor complex [GO:0048179]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell surface [GO:0009986]; endosome [GO:0005768]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	activin binding [GO:0048185]; activin receptor activity, type I [GO:0016361]; ATP binding [GO:0005524]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta-activated receptor activity [GO:0005024]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity, type I [GO:0005025]; type II transforming growth factor beta receptor binding [GO:0005114]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1iata__d1u0eb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d1iaua__d1qa7a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; natural killer cell mediated cytotoxicity [GO:0042267]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; natural killer cell mediated cytotoxicity [GO:0042267]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]	negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1iaua__d2q1ja___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; natural killer cell mediated cytotoxicity [GO:0042267]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; natural killer cell mediated cytotoxicity [GO:0042267]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1ib4a__d2iq7e___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	polygalacturonase activity [GO:0004650]
d1ib4b__d2iq7d___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	polygalacturonase activity [GO:0004650]
d1ib4b__d2z8ga2__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; isopullulanase activity [GO:0051675]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	metabolic process [GO:0008152]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	isopullulanase activity [GO:0051675]
d1ib6a1_d4bqpc___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d1ib6b2_d2v7pa2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	L-lactate dehydrogenase activity [GO:0004459]
d1ib6c1_d1gdhb1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycerate dehydrogenase activity [GO:0008465]; NAD binding [GO:0051287]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]		L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	glycerate dehydrogenase activity [GO:0008465]; NAD binding [GO:0051287]
d1ib6d2_d4ojna2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1ibba__d2yqxa___1			Proteobacteria		periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				periplasmic space [GO:0042597]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	
d1ibda__d2aqma___1			Proteobacteria		periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				periplasmic space [GO:0042597]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	
d1ibgh1_d4w4nb1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ibgh2_d4lgsb___1		Viridiplantae		Streptophyta		endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1ibgl1_d1i8ld___1		Metazoa		Chordata		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]		
d1ibgl2_d1yekl1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ibqa__d1bdla___1	Fungi		Ascomycota		extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ibqb__d2aofb___1	Fungi		Ascomycota		extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ibra__d3tgpa___1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1ibrb__d5xzxa___1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; R-SMAD binding [GO:0070412]; Ran GTPase binding [GO:0008536]; positive regulation of GTPase activity [GO:0043547]; protein export from nucleus [GO:0006611]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	positive regulation of GTPase activity [GO:0043547]; protein export from nucleus [GO:0006611]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	cytoplasm [GO:0005737]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	Ran GTPase binding [GO:0008536]; R-SMAD binding [GO:0070412]
d1ibrd__d4gaab3__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytoplasm [GO:0005737]; leukotriene-A4 hydrolase activity [GO:0004463]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; leukotriene biosynthetic process [GO:0019370]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	leukotriene biosynthetic process [GO:0019370]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	cytoplasm [GO:0005737]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	leukotriene-A4 hydrolase activity [GO:0004463]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]
d1ibt.3_d2qqdg___1			Firmicutes	Euryarchaeota	histidine decarboxylase activity [GO:0004398]; histidine metabolic process [GO:0006547]	arginine decarboxylase activity [GO:0008792]; arginine catabolic process [GO:0006527]	histidine metabolic process [GO:0006547]	arginine catabolic process [GO:0006527]			histidine decarboxylase activity [GO:0004398]	arginine decarboxylase activity [GO:0008792]
d1ibv.1_d1n13.4__1			Firmicutes	Euryarchaeota	histidine decarboxylase activity [GO:0004398]; histidine metabolic process [GO:0006547]	arginine decarboxylase activity [GO:0008792]; arginine catabolic process [GO:0006527]	histidine metabolic process [GO:0006547]	arginine catabolic process [GO:0006527]			histidine decarboxylase activity [GO:0004398]	arginine decarboxylase activity [GO:0008792]
d1ibv.2_d1n2mc___1			Firmicutes	Euryarchaeota	histidine decarboxylase activity [GO:0004398]; histidine metabolic process [GO:0006547]	arginine decarboxylase activity [GO:0008792]; arginine catabolic process [GO:0006527]	histidine metabolic process [GO:0006547]	arginine catabolic process [GO:0006527]			histidine decarboxylase activity [GO:0004398]	arginine decarboxylase activity [GO:0008792]
d1ibv.3_d1n2md___1			Firmicutes	Euryarchaeota	histidine decarboxylase activity [GO:0004398]; histidine metabolic process [GO:0006547]	arginine decarboxylase activity [GO:0008792]; arginine catabolic process [GO:0006527]	histidine metabolic process [GO:0006547]	arginine catabolic process [GO:0006527]			histidine decarboxylase activity [GO:0004398]	arginine decarboxylase activity [GO:0008792]
d1ibw.1_d1n13.6__1			Firmicutes	Euryarchaeota	histidine decarboxylase activity [GO:0004398]; histidine metabolic process [GO:0006547]	arginine decarboxylase activity [GO:0008792]; arginine catabolic process [GO:0006527]	histidine metabolic process [GO:0006547]	arginine catabolic process [GO:0006527]			histidine decarboxylase activity [GO:0004398]	arginine decarboxylase activity [GO:0008792]
d1ibyd__d2hrha2__1		Fungi	Proteobacteria	Basidiomycota	metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]					metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1ibza__d5i6la2__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1ibzb__d1qnif1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	membrane [GO:0016020]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]				membrane [GO:0016020]	metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d1ibzd__d1byob___1		Viridiplantae	Proteobacteria	Streptophyta	metal ion binding [GO:0046872]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				chloroplast thylakoid membrane [GO:0009535]	metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1ic0c__d1fwxb1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]		denitrification pathway [GO:0019333]		membrane [GO:0016020]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d1ic0f__d1tefb___1		Viridiplantae	Proteobacteria	Streptophyta	metal ion binding [GO:0046872]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				chloroplast thylakoid membrane [GO:0009535]	metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1ic1a1_d3q6fg2__1	Metazoa		Chordata		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]		acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]	
d1ic1b1_d1b4jh2__1	Metazoa		Chordata		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]		acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]	
d1ic1b2_d1epfb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]	cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]
d1ic4y__d1g0la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ic4y__d1l7wc___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1ic5h__d2ialc1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ic6a__d1p8ja2__1	Fungi	Metazoa	Ascomycota	Chordata	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d1icjb__d4dr9d___1			Proteobacteria	Cyanobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	translation [GO:0006412]	cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d1ictg__d2h1xb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1icuc__d5j8da___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; 6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]; 2,4,6-trinitrotoluene catabolic process [GO:0046256]	oxidoreductase activity [GO:0016491]	2,4,6-trinitrotoluene catabolic process [GO:0046256]		cytosol [GO:0005829]; membrane [GO:0016020]		6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]	oxidoreductase activity [GO:0016491]
d1icwa__d1rhpd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; chemokine activity [GO:0008009]; interleukin-8 receptor binding [GO:0005153]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; calcium-mediated signaling [GO:0019722]; cell cycle arrest [GO:0007050]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; embryonic digestive tract development [GO:0048566]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of angiogenesis [GO:0045766]; positive regulation of neutrophil chemotaxis [GO:0090023]; receptor internalization [GO:0031623]; regulation of cell adhesion [GO:0030155]; regulation of entry of bacterium into host cell [GO:2000535]; regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045091]; response to endoplasmic reticulum stress [GO:0034976]; response to molecule of bacterial origin [GO:0002237]; signal transduction [GO:0007165]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]; chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; calcium-mediated signaling [GO:0019722]; cell cycle arrest [GO:0007050]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; embryonic digestive tract development [GO:0048566]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of angiogenesis [GO:0045766]; positive regulation of neutrophil chemotaxis [GO:0090023]; receptor internalization [GO:0031623]; regulation of cell adhesion [GO:0030155]; regulation of entry of bacterium into host cell [GO:2000535]; regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045091]; response to endoplasmic reticulum stress [GO:0034976]; response to molecule of bacterial origin [GO:0002237]; signal transduction [GO:0007165]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]	chemokine activity [GO:0008009]; interleukin-8 receptor binding [GO:0005153]	chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]
d1id2b__d5tb7a2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1id2c__d2pp8a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1id3b__d2nqbb___1	Fungi	Metazoa	Ascomycota	Arthropoda	nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; replication fork protection complex [GO:0031298]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; DNA repair [GO:0006281]; negative regulation of transcription by RNA polymerase II [GO:0000122]; transfer RNA gene-mediated silencing [GO:0061587]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; DNA repair [GO:0006281]; negative regulation of transcription by RNA polymerase II [GO:0000122]; transfer RNA gene-mediated silencing [GO:0061587]	chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; replication fork protection complex [GO:0031298]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1id3f__d5gxqc___1	Fungi	Metazoa	Ascomycota	Chordata	nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; replication fork protection complex [GO:0031298]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; DNA repair [GO:0006281]; negative regulation of transcription by RNA polymerase II [GO:0000122]; transfer RNA gene-mediated silencing [GO:0061587]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; DNA repair [GO:0006281]; negative regulation of transcription by RNA polymerase II [GO:0000122]; transfer RNA gene-mediated silencing [GO:0061587]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; replication fork protection complex [GO:0031298]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1idaa__d3kmxa___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d1idbb__d4y38a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1idca__d4aoua___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1idda__d1xcoa1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	acetyl-CoA biosynthetic process [GO:0006085]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	phosphate acetyltransferase activity [GO:0008959]
d1idka__d1idjb___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; pectin lyase activity [GO:0047490]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; pectin lyase activity [GO:0047490]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	pectin lyase activity [GO:0047490]	pectin lyase activity [GO:0047490]
d1idpa__d1gybd___1	Fungi	Fungi	Ascomycota	Ascomycota	endosome [GO:0005768]; metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]; melanin biosynthetic process [GO:0042438]	cytoplasm [GO:0005737]; nuclear envelope [GO:0005635]; nuclear pore central transport channel [GO:0044613]; Ran GTPase binding [GO:0008536]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]	melanin biosynthetic process [GO:0042438]	nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]	endosome [GO:0005768]	cytoplasm [GO:0005737]; nuclear envelope [GO:0005635]; nuclear pore central transport channel [GO:0044613]	metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]	Ran GTPase binding [GO:0008536]
d1idpc__d5ig4e___1	Fungi	Metazoa	Ascomycota	Cnidaria	endosome [GO:0005768]; metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]; melanin biosynthetic process [GO:0042438]	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]	melanin biosynthetic process [GO:0042438]		endosome [GO:0005768]	cytoplasm [GO:0005737]; neuron projection [GO:0043005]	metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]
d1idsa2_d4l2ab2__1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1idsc1_d1xuqa1__1			Actinobacteria	Firmicutes	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	removal of superoxide radicals [GO:0019430]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1idsd1_d3esfb1__1			Actinobacteria		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1idsd2_d4f2nf2__1			Actinobacteria		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	mitochondrion [GO:0005739]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ie3a1_d2dfdc1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d1ie3a1_d4kuea1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]		L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]
d1ie3c1_d2z1md___1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; GDP-mannose 4,6-dehydratase activity [GO:0008446]; NADP+ binding [GO:0070401]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	GDP-mannose 4,6-dehydratase activity [GO:0008446]; NADP+ binding [GO:0070401]
d1ie3c2_d2d4aa2__1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]		L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d1ie4d__d2g2nb___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	periplasmic space [GO:0042597]	hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]
d1ie5a1_d4j12a1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synaptic membrane adhesion [GO:0099560]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synaptic membrane adhesion [GO:0099560]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ieaa2_d4l3cw1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ieac1_d6ehwb1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]			
d1iead1_d2k1ma___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	A band [GO:0031672]; C zone [GO:0014705]; cardiac myofibril [GO:0097512]; cytosol [GO:0005829]; sarcomere [GO:0030017]; striated muscle myosin thick filament [GO:0005863]; actin binding [GO:0003779]; ATPase activator activity [GO:0001671]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; myosin heavy chain binding [GO:0032036]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	A band [GO:0031672]; cardiac myofibril [GO:0097512]; cytosol [GO:0005829]; C zone [GO:0014705]; sarcomere [GO:0030017]; striated muscle myosin thick filament [GO:0005863]		actin binding [GO:0003779]; ATPase activator activity [GO:0001671]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; myosin heavy chain binding [GO:0032036]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]
d1iead2_d4l29k1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1iebb1_d3eo1d2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell development [GO:0048468]; cell-cell junction organization [GO:0045216]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; in utero embryonic development [GO:0001701]; inner ear development [GO:0048839]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell development [GO:0048468]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; inner ear development [GO:0048839]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]		cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]
d1ieea__d1dyaa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ieea__d1gfha___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ieha1_d4u6hb2__1						integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		
d1ieja__d1mdqa___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1iesb__d3e1ol___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1iewa1_d3i3eb3__1	Viridiplantae		Streptophyta	Proteobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1if1b__d2o6ge___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; apoptotic process [GO:0006915]; CD8-positive, alpha-beta T cell differentiation [GO:0043374]; cell cycle arrest [GO:0007050]; cellular response to interferon-beta [GO:0035458]; cellular response to interleukin-1 [GO:0071347]; cellular response to mechanical stimulus [GO:0071260]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to tumor necrosis factor [GO:0071356]; defense response to virus [GO:0051607]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of cell death [GO:0010942]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; regulation of adaptive immune response [GO:0002819]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564]; regulation of gene expression [GO:0010468]; regulation of innate immune response [GO:0045088]; regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034124]; response to growth hormone [GO:0060416]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	apoptotic process [GO:0006915]; CD8-positive, alpha-beta T cell differentiation [GO:0043374]; cell cycle arrest [GO:0007050]; cellular response to interferon-beta [GO:0035458]; cellular response to interleukin-1 [GO:0071347]; cellular response to mechanical stimulus [GO:0071260]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to tumor necrosis factor [GO:0071356]; defense response to virus [GO:0051607]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of cell death [GO:0010942]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of adaptive immune response [GO:0002819]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564]; regulation of gene expression [GO:0010468]; regulation of innate immune response [GO:0045088]; regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034124]; response to growth hormone [GO:0060416]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]
d1if6a__d5tv3c___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1ifca__d2ozqa___1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]
d1ifhl2_d2fb4h2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ifhl2_d5whjl1__1												
d1ifsa__d3hiva___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1ifta__d3ktza___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1ifva__d5aeua2__1	Viridiplantae		Streptophyta	Proteobacteria	cytosol [GO:0005829]; abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]	aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]		abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1ifvb__d3gcfg2__1	Viridiplantae		Streptophyta	Actinobacteria	cytosol [GO:0005829]; abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]		cytosol [GO:0005829]		abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1ig5a__d1d1oa___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]			apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]
d1ig5a__d1xk4e___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1ig8a2_d1qhaa3__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; cellular glucose homeostasis [GO:0001678]; fructose import [GO:0032445]; fructose metabolic process [GO:0006000]; glucose import [GO:0046323]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013]; regulation of cell size [GO:0008361]; regulation of transcription by glucose [GO:0046015]; replicative cell aging [GO:0001302]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cellular glucose homeostasis [GO:0001678]; fructose import [GO:0032445]; fructose metabolic process [GO:0006000]; glucose import [GO:0046323]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013]; regulation of cell size [GO:0008361]; regulation of transcription by glucose [GO:0046015]; replicative cell aging [GO:0001302]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1igch2_d3bevb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]		protein homodimerization activity [GO:0042803]
d1igcl2_d1nj9b1__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1igfh2_d2qr0k1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1igfj1_d2gfbk1__1												
d1igfj1_d3vwkb___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1igfl1_d4k3em1__1		Metazoa		Chordata								
d1igfl2_d2jjsa___1		Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; thrombospondin receptor activity [GO:0070053]; cell migration [GO:0016477]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; neutrophil degranulation [GO:0043312]; opsonization [GO:0008228]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of inflammatory response [GO:0050729]; positive regulation of phagocytosis [GO:0050766]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell activation [GO:0050870]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-10 production [GO:0032653]; regulation of interleukin-12 production [GO:0032655]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]; response to bacterium [GO:0009617]		cell migration [GO:0016477]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; neutrophil degranulation [GO:0043312]; opsonization [GO:0008228]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of inflammatory response [GO:0050729]; positive regulation of phagocytosis [GO:0050766]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell activation [GO:0050870]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-10 production [GO:0032653]; regulation of interleukin-12 production [GO:0032655]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]; response to bacterium [GO:0009617]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; thrombospondin receptor activity [GO:0070053]
d1igfm1_d1rfdl1__1												
d1igfm1_d1w72a1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1igih2_d2r2ea2__1												
d1igil1_d2uweb2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1igja1_d4n0fe2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1igjb1_d1es0a1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]		
d1igjb2_d2bsra1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1igjc2_d1yedl1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1igjd1_d4nqch2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1igmh__d4at6l2__1												
d1igmh__d5c9kd1__1		Metazoa		Chordata								
d1igoa__d4uwta___1		Fungi	Firmicutes	Ascomycota	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d1igra1_d3g3ae___1	Metazoa	Metazoa	Chordata	Chordata	alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; axon [GO:0030424]; cell [GO:0005623]; insulin receptor complex [GO:0005899]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; insulin-activated receptor activity [GO:0005009]; insulin-like growth factor binding [GO:0005520]; insulin-like growth factor I binding [GO:0031994]; insulin-like growth factor-activated receptor activity [GO:0005010]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein transporter activity [GO:0140318]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; amyloid-beta clearance [GO:0097242]; anatomical structure development [GO:0048856]; cellular response to amyloid-beta [GO:1904646]; cellular response to glucose stimulus [GO:0071333]; dendritic spine maintenance [GO:0097062]; glucose homeostasis [GO:0042593]; immune response [GO:0006955]; inactivation of MAPKK activity [GO:0051389]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase B signaling [GO:0051897]; protein autophosphorylation [GO:0046777]; protein tetramerization [GO:0051262]; regulation of JNK cascade [GO:0046328]; signal transduction [GO:0007165]; transcytosis [GO:0045056]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid-beta clearance [GO:0097242]; anatomical structure development [GO:0048856]; cellular response to amyloid-beta [GO:1904646]; cellular response to glucose stimulus [GO:0071333]; dendritic spine maintenance [GO:0097062]; glucose homeostasis [GO:0042593]; immune response [GO:0006955]; inactivation of MAPKK activity [GO:0051389]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase B signaling [GO:0051897]; protein autophosphorylation [GO:0046777]; protein tetramerization [GO:0051262]; regulation of JNK cascade [GO:0046328]; signal transduction [GO:0007165]; transcytosis [GO:0045056]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; axon [GO:0030424]; cell [GO:0005623]; insulin receptor complex [GO:0005899]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; insulin-activated receptor activity [GO:0005009]; insulin binding [GO:0043559]; insulin-like growth factor-activated receptor activity [GO:0005010]; insulin-like growth factor binding [GO:0005520]; insulin-like growth factor I binding [GO:0031994]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein transporter activity [GO:0140318]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1igta2_d3pp3k1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1igtb2_d2uv3a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]
d1igtc1_d2b4cl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1igtd1_d3lmjl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1igtd2_d4llaa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cell adhesion molecule binding [GO:0050839]; inhibitory MHC class I receptor activity [GO:0032396]; MHC class I protein binding [GO:0042288]; MHC class Ib protein binding [GO:0023029]; MHC class Ib protein complex binding [GO:0023025]; protein homodimerization activity [GO:0042803]; protein phosphatase 1 binding [GO:0008157]; protein-containing complex binding [GO:0044877]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; cellular response to lipopolysaccharide [GO:0071222]; Fc receptor mediated inhibitory signaling pathway [GO:0002774]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; immune response-inhibiting cell surface receptor signaling pathway [GO:0002767]; learning or memory [GO:0007611]; negative regulation of antigen processing and presentation [GO:0002578]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of postsynaptic density organization [GO:1905875]; negative regulation of protein metabolic process [GO:0051248]; negative regulation of T cell proliferation [GO:0042130]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T cell tolerance induction [GO:0002666]; positive regulation of tolerance induction [GO:0002645]; regulation of dendritic cell differentiation [GO:2001198]; regulation of immune response [GO:0050776]; regulation of long-term synaptic potentiation [GO:1900271]; signal transduction [GO:0007165]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	adaptive immune response [GO:0002250]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to lipopolysaccharide [GO:0071222]; Fc receptor mediated inhibitory signaling pathway [GO:0002774]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; immune response-inhibiting cell surface receptor signaling pathway [GO:0002767]; learning or memory [GO:0007611]; negative regulation of antigen processing and presentation [GO:0002578]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of postsynaptic density organization [GO:1905875]; negative regulation of protein metabolic process [GO:0051248]; negative regulation of T cell proliferation [GO:0042130]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T cell tolerance induction [GO:0002666]; positive regulation of tolerance induction [GO:0002645]; regulation of dendritic cell differentiation [GO:2001198]; regulation of immune response [GO:0050776]; regulation of long-term synaptic potentiation [GO:1900271]; signal transduction [GO:0007165]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	amyloid-beta binding [GO:0001540]; cell adhesion molecule binding [GO:0050839]; inhibitory MHC class I receptor activity [GO:0032396]; MHC class Ib protein binding [GO:0023029]; MHC class Ib protein complex binding [GO:0023025]; MHC class I protein binding [GO:0042288]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; protein phosphatase 1 binding [GO:0008157]
d1igtd3_d1h5bd___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1igwc__d1oqfb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; cation binding [GO:0043169]; isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	magnesium ion binding [GO:0000287]; methylisocitrate lyase activity [GO:0046421]; propionate catabolic process, 2-methylcitrate cycle [GO:0019629]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	propionate catabolic process, 2-methylcitrate cycle [GO:0019629]	cytosol [GO:0005829]		cation binding [GO:0043169]; isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; methylisocitrate lyase activity [GO:0046421]
d1igxa1_d4c51b1__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]
d1igyb1_d5d7jh2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1igyb3_d1xf2a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1igyb4_d4tscl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1igyc2_d1xmwa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SH3 domain binding [GO:0017124]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; lymphocyte activation [GO:0046649]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; response to nutrient [GO:0007584]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; lymphocyte activation [GO:0046649]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; response to nutrient [GO:0007584]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SH3 domain binding [GO:0017124]; transmembrane signaling receptor activity [GO:0004888]
d1igyd2_d5iieb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ih8a__d1o96d1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]; NAD biosynthetic process [GO:0009435]; sporulation resulting in formation of a cellular spore [GO:0030435]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	NAD biosynthetic process [GO:0009435]; sporulation resulting in formation of a cellular spore [GO:0030435]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]
d1ihca__d5ersa2__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]
d1ihfb__d3c4ia___1			Proteobacteria		chromosome [GO:0005694]; cytosol [GO:0005829]; DNA binding [GO:0003677]; conjugation [GO:0000746]; DNA recombination [GO:0006310]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]		conjugation [GO:0000746]; DNA recombination [GO:0006310]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]		chromosome [GO:0005694]; cytosol [GO:0005829]		DNA binding [GO:0003677]	
d1ihia__d1ry8a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]; 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; prostaglandin-F synthase activity [GO:0047017]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]	cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin-F synthase activity [GO:0047017]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]
d1ihjb__d2ehra1__1	Metazoa	Metazoa	Arthropoda	Chordata	inaD signaling complex [GO:0016027]; rhabdomere [GO:0016028]; calmodulin binding [GO:0005516]; myosin binding [GO:0017022]; myosin III binding [GO:0031473]; photoreceptor activity [GO:0009881]; receptor signaling complex adaptor activity [GO:0030159]; cellular response to light stimulus [GO:0071482]; deactivation of rhodopsin mediated signaling [GO:0016059]; detection of light stimulus involved in sensory perception [GO:0050962]; phototransduction [GO:0007602]; protein localization [GO:0008104]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	cellular response to light stimulus [GO:0071482]; deactivation of rhodopsin mediated signaling [GO:0016059]; detection of light stimulus involved in sensory perception [GO:0050962]; phototransduction [GO:0007602]; protein localization [GO:0008104]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601]	bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	inaD signaling complex [GO:0016027]; rhabdomere [GO:0016028]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	calmodulin binding [GO:0005516]; myosin binding [GO:0017022]; myosin III binding [GO:0031473]; photoreceptor activity [GO:0009881]; receptor signaling complex adaptor activity [GO:0030159]	
d1iht.1_d3mmgb___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	helical viral capsid [GO:0019029]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]; RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	helical viral capsid [GO:0019029]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]
d1ihxb2_d1cerd2__1	Metazoa		Arthropoda	Deinococcus-Thermus	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1ihxc2_d1gypc2__1	Metazoa		Arthropoda		cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	glycosome [GO:0020015]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1ihyc2_d2pkrm2__1	Metazoa	Viridiplantae	Arthropoda	Streptophyta	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1ii2b2_d4woua1__1				Actinobacteria	glycosome [GO:0020015]; ATP binding [GO:0005524]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; gluconeogenesis [GO:0006094]	gluconeogenesis [GO:0006094]	gluconeogenesis [GO:0006094]	glycosome [GO:0020015]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]	GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]
d1ii4d__d3ud7b___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1ii4g1_d1j86b2__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	Fc-epsilon receptor signaling pathway [GO:0038095]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	IgE binding [GO:0019863]
d1ii5a1_d2y7kb1__1			Cyanobacteria	Proteobacteria	integral component of membrane [GO:0016021]; ligand-gated ion channel activity [GO:0015276]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]			integral component of membrane [GO:0016021]		ligand-gated ion channel activity [GO:0015276]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1iibb__d5dleb___1			Proteobacteria	Spirochaetes	cytosol [GO:0005829]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity [GO:0090566]; N,N'-diacetylchitobiose import [GO:1902815]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]; carbohydrate:proton symporter activity [GO:0005351]; protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity [GO:0022877]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	N,N'-diacetylchitobiose import [GO:1902815]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytosol [GO:0005829]	integral component of membrane [GO:0016021]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity [GO:0090566]	carbohydrate:proton symporter activity [GO:0005351]; protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity [GO:0022877]
d1iida1_d2nmta1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; replicative cell aging [GO:0001302]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; replicative cell aging [GO:0001302]	N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; replicative cell aging [GO:0001302]	N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; replicative cell aging [GO:0001302]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d1iida1_d4j3gc___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; replicative cell aging [GO:0001302]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]	N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; replicative cell aging [GO:0001302]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]
d1iiia__d2h6uh___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1iild__d2kkia___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; copper ion binding [GO:0005507]; cytokine activity [GO:0005125]; interleukin-1 receptor binding [GO:0005149]; apoptotic process [GO:0006915]; cellular response to heat [GO:0034605]; cellular response to lipopolysaccharide [GO:0071222]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; immune response [GO:0006955]; interleukin-1-mediated signaling pathway [GO:0070498]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of protein secretion [GO:0050714]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; response to copper ion [GO:0046688]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	apoptotic process [GO:0006915]; cellular response to heat [GO:0034605]; cellular response to lipopolysaccharide [GO:0071222]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; immune response [GO:0006955]; interleukin-1-mediated signaling pathway [GO:0070498]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of protein secretion [GO:0050714]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; response to copper ion [GO:0046688]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	copper ion binding [GO:0005507]; cytokine activity [GO:0005125]; interleukin-1 receptor binding [GO:0005149]
d1iild__d3fjia1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1iile1_d4hbqb2__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; integrin binding involved in cell-matrix adhesion [GO:0098640]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	integrin binding involved in cell-matrix adhesion [GO:0098640]
d1iilf1_d5iueh___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1iilg1_d5mp2d1__1	Metazoa		Chordata	Proteobacteria	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; type II protein secretion system complex [GO:0015627]; identical protein binding [GO:0042802]; protein secretion by the type II secretion system [GO:0015628]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	protein secretion by the type II secretion system [GO:0015628]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; type II protein secretion system complex [GO:0015627]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	identical protein binding [GO:0042802]
d1iilg2_d1c1el1__1	Metazoa		Chordata		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]		angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	
d1iima__d3zlkd___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]			glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1iina__d4b4md___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]			glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1iiqb__d3ektc___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1iisb3_d4ob5l1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; monomeric IgA immunoglobulin complex [GO:0071748]; pentameric IgM immunoglobulin complex [GO:0071756]; plasma membrane [GO:0005886]; secretory IgA immunoglobulin complex [GO:0071751]; antigen binding [GO:0003823]; antibacterial humoral response [GO:0019731]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		antibacterial humoral response [GO:0019731]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; monomeric IgA immunoglobulin complex [GO:0071748]; pentameric IgM immunoglobulin complex [GO:0071756]; plasma membrane [GO:0005886]; secretory IgA immunoglobulin complex [GO:0071751]		antigen binding [GO:0003823]
d1iiua__d2r73d___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated vesicle [GO:0030136]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; yolk [GO:0060417]; yolk plasma [GO:0060418]; protein domain specific binding [GO:0019904]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]; signaling receptor binding [GO:0005102]; eye development [GO:0001654]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; maintenance of gastrointestinal epithelium [GO:0030277]; oocyte growth [GO:0001555]; positive regulation of insulin secretion [GO:0032024]; protein-containing complex assembly [GO:0065003]; response to estrogen [GO:0043627]; response to retinoic acid [GO:0032526]; response to virus [GO:0009615]; response to vitamin A [GO:0033189]; retinol metabolic process [GO:0042572]	extracellular region [GO:0005576]; small molecule binding [GO:0036094]	eye development [GO:0001654]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; maintenance of gastrointestinal epithelium [GO:0030277]; oocyte growth [GO:0001555]; positive regulation of insulin secretion [GO:0032024]; protein-containing complex assembly [GO:0065003]; response to estrogen [GO:0043627]; response to retinoic acid [GO:0032526]; response to virus [GO:0009615]; response to vitamin A [GO:0033189]; retinol metabolic process [GO:0042572]		clathrin-coated vesicle [GO:0030136]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; yolk [GO:0060417]; yolk plasma [GO:0060418]	extracellular region [GO:0005576]	protein domain specific binding [GO:0019904]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]; signaling receptor binding [GO:0005102]	small molecule binding [GO:0036094]
d1iiza__d2bqoa___1	Metazoa	Metazoa	Arthropoda	Chordata	lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ij7b__d1tala___1				Proteobacteria		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]				extracellular region [GO:0005576]		serine-type endopeptidase activity [GO:0004252]
d1ij9a2_d1i1ad2__1	Metazoa	Metazoa	Chordata	Chordata	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell chemotaxis [GO:0060326]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]	
d1ijea1_d1aipf1__1	Fungi		Ascomycota	Deinococcus-Thermus	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]		cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]	cytoplasm [GO:0005737]	guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1ijea1_d1yi2b1__1	Fungi		Ascomycota	Euryarchaeota	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	translation [GO:0006412]	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]	ribosome [GO:0005840]	guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1ijfa1_d1u2ra1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]	guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]
d1ijfa2_d2ahoa2__1	Fungi		Ascomycota	Crenarchaeota	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]	cytosol [GO:0005829]	guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1ijfa2_d4rd0a3__1	Fungi		Ascomycota	Crenarchaeota	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]	cytosol [GO:0005829]	guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1ijja2_d4h5ta2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1ijjb1_d4fpbb3__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1ijjb2_d4f9oa4__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1ijkb__d2os9b1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1ijlb__d3g8fa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1ijta__d3wo3g___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; apoptotic process involved in morphogenesis [GO:0060561]; cartilage condensation [GO:0001502]; cell-cell signaling [GO:0007267]; cellular response to leukemia inhibitory factor [GO:1990830]; chondroblast differentiation [GO:0060591]; cranial suture morphogenesis [GO:0060363]; embryonic hindlimb morphogenesis [GO:0035116]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; mesenchymal cell proliferation [GO:0010463]; negative regulation of apoptotic process [GO:0043066]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; signal transduction [GO:0007165]; stem cell population maintenance [GO:0019827]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	apoptotic process involved in morphogenesis [GO:0060561]; cartilage condensation [GO:0001502]; cell-cell signaling [GO:0007267]; cellular response to leukemia inhibitory factor [GO:1990830]; chondroblast differentiation [GO:0060591]; cranial suture morphogenesis [GO:0060363]; embryonic hindlimb morphogenesis [GO:0035116]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; mesenchymal cell proliferation [GO:0010463]; negative regulation of apoptotic process [GO:0043066]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; signal transduction [GO:0007165]; stem cell population maintenance [GO:0019827]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d1ijxa__d5bpqa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Wnt-protein binding [GO:0017147]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; convergent extension involved in organogenesis [GO:0060029]; inner ear morphogenesis [GO:0042472]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cartilage development [GO:0061037]; negative regulation of cell development [GO:0010721]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hepatocyte differentiation [GO:0070367]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; non-canonical Wnt signaling pathway [GO:0035567]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fat cell differentiation [GO:0045600]; somite development [GO:0061053]	cell surface [GO:0009986]; cell-cell junction [GO:0005911]; clathrin-coated endocytic vesicle membrane [GO:0030669]; clathrin-coated vesicle membrane [GO:0030665]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; G protein-coupled receptor activity [GO:0004930]; PDZ domain binding [GO:0030165]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; canonical Wnt signaling pathway [GO:0060070]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to retinoic acid [GO:0071300]; cerebellum vasculature morphogenesis [GO:0061301]; extracellular matrix-cell signaling [GO:0035426]; locomotion involved in locomotory behavior [GO:0031987]; membrane organization [GO:0061024]; negative regulation of cell-substrate adhesion [GO:0010812]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; Norrin signaling pathway [GO:0110135]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of transcription, DNA-templated [GO:0045893]; progesterone secretion [GO:0042701]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal blood vessel morphogenesis [GO:0061304]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; convergent extension involved in organogenesis [GO:0060029]; inner ear morphogenesis [GO:0042472]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cartilage development [GO:0061037]; negative regulation of cell development [GO:0010721]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hepatocyte differentiation [GO:0070367]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; non-canonical Wnt signaling pathway [GO:0035567]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fat cell differentiation [GO:0045600]; somite development [GO:0061053]	canonical Wnt signaling pathway [GO:0060070]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to retinoic acid [GO:0071300]; cerebellum vasculature morphogenesis [GO:0061301]; extracellular matrix-cell signaling [GO:0035426]; locomotion involved in locomotory behavior [GO:0031987]; membrane organization [GO:0061024]; negative regulation of cell-substrate adhesion [GO:0010812]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; Norrin signaling pathway [GO:0110135]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of transcription, DNA-templated [GO:0045893]; progesterone secretion [GO:0042701]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; retinal blood vessel morphogenesis [GO:0061304]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell-cell junction [GO:0005911]; cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; clathrin-coated vesicle membrane [GO:0030665]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	Wnt-protein binding [GO:0017147]	amyloid-beta binding [GO:0001540]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; G protein-coupled receptor activity [GO:0004930]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]
d1ijxd__d5t44a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Wnt-protein binding [GO:0017147]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; convergent extension involved in organogenesis [GO:0060029]; inner ear morphogenesis [GO:0042472]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cartilage development [GO:0061037]; negative regulation of cell development [GO:0010721]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hepatocyte differentiation [GO:0070367]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; non-canonical Wnt signaling pathway [GO:0035567]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fat cell differentiation [GO:0045600]; somite development [GO:0061053]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; frizzled binding [GO:0005109]; G protein-coupled receptor activity [GO:0004930]; PDZ domain binding [GO:0030165]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; canonical Wnt signaling pathway [GO:0060070]; cellular response to retinoic acid [GO:0071300]; mesenchymal to epithelial transition [GO:0060231]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of ectodermal cell fate specification [GO:0042666]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; non-canonical Wnt signaling pathway via JNK cascade [GO:0038031]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of JNK cascade [GO:0046330]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of transcription, DNA-templated [GO:0006355]; skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration [GO:0014834]; somatic stem cell division [GO:0048103]; stem cell population maintenance [GO:0019827]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell differentiation in thymus [GO:0033077]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; convergent extension involved in organogenesis [GO:0060029]; inner ear morphogenesis [GO:0042472]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cartilage development [GO:0061037]; negative regulation of cell development [GO:0010721]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hepatocyte differentiation [GO:0070367]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; non-canonical Wnt signaling pathway [GO:0035567]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fat cell differentiation [GO:0045600]; somite development [GO:0061053]	canonical Wnt signaling pathway [GO:0060070]; cellular response to retinoic acid [GO:0071300]; mesenchymal to epithelial transition [GO:0060231]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of ectodermal cell fate specification [GO:0042666]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; non-canonical Wnt signaling pathway via JNK cascade [GO:0038031]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of JNK cascade [GO:0046330]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of transcription, DNA-templated [GO:0006355]; skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration [GO:0014834]; somatic stem cell division [GO:0048103]; stem cell population maintenance [GO:0019827]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell differentiation in thymus [GO:0033077]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	Wnt-protein binding [GO:0017147]	frizzled binding [GO:0005109]; G protein-coupled receptor activity [GO:0004930]; PDZ domain binding [GO:0030165]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]
d1ijxf__d5bqcb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Wnt-protein binding [GO:0017147]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; convergent extension involved in organogenesis [GO:0060029]; inner ear morphogenesis [GO:0042472]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cartilage development [GO:0061037]; negative regulation of cell development [GO:0010721]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hepatocyte differentiation [GO:0070367]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; non-canonical Wnt signaling pathway [GO:0035567]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fat cell differentiation [GO:0045600]; somite development [GO:0061053]	cell surface [GO:0009986]; cell-cell junction [GO:0005911]; clathrin-coated endocytic vesicle membrane [GO:0030669]; clathrin-coated vesicle membrane [GO:0030665]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; G protein-coupled receptor activity [GO:0004930]; PDZ domain binding [GO:0030165]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; canonical Wnt signaling pathway [GO:0060070]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to retinoic acid [GO:0071300]; cerebellum vasculature morphogenesis [GO:0061301]; extracellular matrix-cell signaling [GO:0035426]; locomotion involved in locomotory behavior [GO:0031987]; membrane organization [GO:0061024]; negative regulation of cell-substrate adhesion [GO:0010812]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; Norrin signaling pathway [GO:0110135]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of transcription, DNA-templated [GO:0045893]; progesterone secretion [GO:0042701]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal blood vessel morphogenesis [GO:0061304]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; convergent extension involved in organogenesis [GO:0060029]; inner ear morphogenesis [GO:0042472]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cartilage development [GO:0061037]; negative regulation of cell development [GO:0010721]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hepatocyte differentiation [GO:0070367]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; non-canonical Wnt signaling pathway [GO:0035567]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fat cell differentiation [GO:0045600]; somite development [GO:0061053]	canonical Wnt signaling pathway [GO:0060070]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to retinoic acid [GO:0071300]; cerebellum vasculature morphogenesis [GO:0061301]; extracellular matrix-cell signaling [GO:0035426]; locomotion involved in locomotory behavior [GO:0031987]; membrane organization [GO:0061024]; negative regulation of cell-substrate adhesion [GO:0010812]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; Norrin signaling pathway [GO:0110135]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of transcription, DNA-templated [GO:0045893]; progesterone secretion [GO:0042701]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; retinal blood vessel morphogenesis [GO:0061304]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell-cell junction [GO:0005911]; cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; clathrin-coated vesicle membrane [GO:0030665]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	Wnt-protein binding [GO:0017147]	amyloid-beta binding [GO:0001540]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; G protein-coupled receptor activity [GO:0004930]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]
d1ijya__d5urza___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; Wnt-Frizzled-LRP5/6 complex [GO:1990851]; G protein-coupled receptor activity [GO:0004930]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; angiogenesis [GO:0001525]; canonical Wnt signaling pathway [GO:0060070]; non-canonical Wnt signaling pathway [GO:0035567]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein phosphorylation [GO:0001934]; T cell differentiation in thymus [GO:0033077]; Wnt signaling pathway [GO:0016055]	axon [GO:0030424]; bicellular tight junction [GO:0005923]; cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; G protein-coupled receptor activity [GO:0004930]; lipid binding [GO:0008289]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; ubiquitin protein ligase binding [GO:0031625]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; angiogenesis [GO:0001525]; anterior/posterior axis specification, embryo [GO:0008595]; apoptotic process involved in morphogenesis [GO:0060561]; beta-catenin destruction complex disassembly [GO:1904886]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; canonical Wnt signaling pathway [GO:0060070]; cell maturation [GO:0048469]; cellular response to molecule of bacterial origin [GO:0071219]; chorionic trophoblast cell differentiation [GO:0060718]; embryonic axis specification [GO:0000578]; embryonic camera-type eye morphogenesis [GO:0048596]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of cell population proliferation [GO:0008285]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor secretion [GO:1904469]; post-embryonic camera-type eye development [GO:0031077]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of chorionic trophoblast cell proliferation [GO:1901382]; Spemann organizer formation [GO:0060061]; synapse assembly [GO:0007416]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell differentiation in thymus [GO:0033077]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	angiogenesis [GO:0001525]; canonical Wnt signaling pathway [GO:0060070]; non-canonical Wnt signaling pathway [GO:0035567]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein phosphorylation [GO:0001934]; T cell differentiation in thymus [GO:0033077]; Wnt signaling pathway [GO:0016055]	angiogenesis [GO:0001525]; anterior/posterior axis specification, embryo [GO:0008595]; apoptotic process involved in morphogenesis [GO:0060561]; beta-catenin destruction complex disassembly [GO:1904886]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; canonical Wnt signaling pathway [GO:0060070]; cell maturation [GO:0048469]; cellular response to molecule of bacterial origin [GO:0071219]; chorionic trophoblast cell differentiation [GO:0060718]; embryonic axis specification [GO:0000578]; embryonic camera-type eye morphogenesis [GO:0048596]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of cell population proliferation [GO:0008285]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor secretion [GO:1904469]; post-embryonic camera-type eye development [GO:0031077]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of chorionic trophoblast cell proliferation [GO:1901382]; Spemann organizer formation [GO:0060061]; synapse assembly [GO:0007416]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell differentiation in thymus [GO:0033077]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; Wnt-Frizzled-LRP5/6 complex [GO:1990851]	axon [GO:0030424]; bicellular tight junction [GO:0005923]; cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	G protein-coupled receptor activity [GO:0004930]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]	amyloid-beta binding [GO:0001540]; G protein-coupled receptor activity [GO:0004930]; lipid binding [GO:0008289]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; ubiquitin protein ligase binding [GO:0031625]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]
d1ik4a__d1s89e___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	methylglyoxal synthase activity [GO:0008929]
d1ik4c__d1s8af___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	methylglyoxal synthase activity [GO:0008929]
d1ik4e__d2b0wa1__1			Proteobacteria		cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]		methylglyoxal biosynthetic process [GO:0019242]		cytosol [GO:0005829]		methylglyoxal synthase activity [GO:0008929]	
d1ikfh1_d3l3ib___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ikfh2_d2a1wi1__1		Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d1ikfl2_d4ww2a2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ikja__d5jr8b___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	vasodilation [GO:0042311]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1ikna1_d1tg8a1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; serine-type peptidase activity [GO:0008236]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; serine-type peptidase activity [GO:0008236]
d1ikta__d4av7b2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]; alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]		cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]		17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]
d1ikua__d1zfsb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; calcium ion binding [GO:0005509]; phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	A band [GO:0031672]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; I band [GO:0031674]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]	phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	A band [GO:0031672]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; I band [GO:0031674]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	calcium ion binding [GO:0005509]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]
d1il0a2_d4qsme1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1il1b1_d1n3na1__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1il1b2_d1fe8l1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1il2b1_d1asza1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	aspartyl-tRNA aminoacylation [GO:0006422]	aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]
d1il3a__d4zgra___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1il6a__d1higb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular respiration [GO:1901857]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of iron ion import across plasma membrane [GO:1904440]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vitamin D biosynthetic process [GO:0060557]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein ADP-ribosylation [GO:0010835]; regulation of regulatory T cell differentiation [GO:0045589]; response to virus [GO:0009615]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular respiration [GO:1901857]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of iron ion import across plasma membrane [GO:1904440]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vitamin D biosynthetic process [GO:0060557]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein ADP-ribosylation [GO:0010835]; regulation of regulatory T cell differentiation [GO:0045589]; response to virus [GO:0009615]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]	cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]
d1il6a__d3n0pa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]	hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]
d1ilea1_d2x1ma2__1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; isoleucyl-tRNA aminoacylation [GO:0006428]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	isoleucyl-tRNA aminoacylation [GO:0006428]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]
d1iloa__d3uiwb___1		Metazoa	Euryarchaeota	Chordata	protein disulfide oxidoreductase activity [GO:0015035]; cellular oxidant detoxification [GO:0098869]	cell [GO:0005623]; cytosol [GO:0005829]; electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; heart formation [GO:0060914]; neural crest cell migration [GO:0001755]; neural crest cell migration involved in heart formation [GO:0003147]; protein deglutathionylation [GO:0080058]; vasculature development [GO:0001944]	cellular oxidant detoxification [GO:0098869]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; heart formation [GO:0060914]; neural crest cell migration [GO:0001755]; neural crest cell migration involved in heart formation [GO:0003147]; protein deglutathionylation [GO:0080058]; vasculature development [GO:0001944]		cell [GO:0005623]; cytosol [GO:0005829]	protein disulfide oxidoreductase activity [GO:0015035]	electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]
d1ilpb__d1pfmd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; chemokine activity [GO:0008009]; interleukin-8 receptor binding [GO:0005153]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; calcium-mediated signaling [GO:0019722]; cell cycle arrest [GO:0007050]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; embryonic digestive tract development [GO:0048566]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of angiogenesis [GO:0045766]; positive regulation of neutrophil chemotaxis [GO:0090023]; receptor internalization [GO:0031623]; regulation of cell adhesion [GO:0030155]; regulation of entry of bacterium into host cell [GO:2000535]; regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045091]; response to endoplasmic reticulum stress [GO:0034976]; response to molecule of bacterial origin [GO:0002237]; signal transduction [GO:0007165]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]; chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; calcium-mediated signaling [GO:0019722]; cell cycle arrest [GO:0007050]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; embryonic digestive tract development [GO:0048566]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of angiogenesis [GO:0045766]; positive regulation of neutrophil chemotaxis [GO:0090023]; receptor internalization [GO:0031623]; regulation of cell adhesion [GO:0030155]; regulation of entry of bacterium into host cell [GO:2000535]; regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045091]; response to endoplasmic reticulum stress [GO:0034976]; response to molecule of bacterial origin [GO:0002237]; signal transduction [GO:0007165]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]	chemokine activity [GO:0008009]; interleukin-8 receptor binding [GO:0005153]	chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]
d1ilr1__d2ntdb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; interleukin-1 type I receptor antagonist activity [GO:0045352]; interleukin-1 type II receptor antagonist activity [GO:0045353]; interleukin-1, type I receptor binding [GO:0005150]; interleukin-1, type II receptor binding [GO:0005151]; acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; interleukin-1-mediated signaling pathway [GO:0070498]; lipid metabolic process [GO:0006629]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; response to glucocorticoid [GO:0051384]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; interleukin-1-mediated signaling pathway [GO:0070498]; lipid metabolic process [GO:0006629]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; response to glucocorticoid [GO:0051384]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytokine activity [GO:0005125]; interleukin-1, type II receptor binding [GO:0005151]; interleukin-1, type I receptor binding [GO:0005150]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; interleukin-1 type II receptor antagonist activity [GO:0045353]; interleukin-1 type I receptor antagonist activity [GO:0045352]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1ilsc__d4e9pa1__1			Proteobacteria		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	
d1ilsc__d4pcya___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1ilub__d1kyaa2__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1ilub__d2i7sa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1ilue__d2ppca2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1ilug__d4fa7b2__1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1iluh__d1cuoa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1iluk__d5n0ka1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	anchored component of plasma membrane [GO:0046658]; cell [GO:0005623]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; aging [GO:0007568]; cellular iron ion homeostasis [GO:0006879]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; liver development [GO:0001889]; lung development [GO:0030324]; plasma membrane copper ion transport [GO:0015679]; response to copper ion [GO:0046688]; response to nutrient [GO:0007584]	oxidation-reduction process [GO:0055114]	aging [GO:0007568]; cellular iron ion homeostasis [GO:0006879]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; liver development [GO:0001889]; lung development [GO:0030324]; plasma membrane copper ion transport [GO:0015679]; response to copper ion [GO:0046688]; response to nutrient [GO:0007584]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	anchored component of plasma membrane [GO:0046658]; cell [GO:0005623]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d1ilum__d2vmja2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1ilya__d2vqfk1__1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1im3a2_d4pj7a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1im3e1_d1zhla1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1im3h__d1ok8a1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1im3i1_d1deeb1__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	pathogenesis [GO:0009405]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	IgG binding [GO:0019864]
d1im3j2_d4wgvd___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1im9a1_d4xcel2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1im9d2_d1wc7h1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1imja__d1scia___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hydrolase activity [GO:0016787]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; positive regulation of transcription by RNA polymerase II [GO:0045944]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; positive regulation of transcription by RNA polymerase II [GO:0045944]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		hydrolase activity [GO:0016787]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]
d1imoa1_d1t2vc1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; DNA ligase III-XRCC1 complex [GO:0070421]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA ligase (ATP) activity [GO:0003910]; DNA ligase activity [GO:0003909]; zinc ion binding [GO:0008270]; base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; lagging strand elongation [GO:0006273]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; transcription-coupled nucleotide-excision repair [GO:0006283]	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; gamma-tubulin ring complex [GO:0008274]; lateral element [GO:0000800]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151]; androgen receptor binding [GO:0050681]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; androgen receptor signaling pathway [GO:0030521]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to indole-3-methanol [GO:0071681]; cellular response to tumor necrosis factor [GO:0071356]; centrosome cycle [GO:0007098]; chordate embryonic development [GO:0043009]; chromosome segregation [GO:0007059]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; fatty acid biosynthetic process [GO:0006633]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of centriole replication [GO:0046600]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of DNA repair [GO:0045739]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of histone H4-K20 methylation [GO:0070512]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; response to estrogen [GO:0043627]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; lagging strand elongation [GO:0006273]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; transcription-coupled nucleotide-excision repair [GO:0006283]	androgen receptor signaling pathway [GO:0030521]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to indole-3-methanol [GO:0071681]; cellular response to tumor necrosis factor [GO:0071356]; centrosome cycle [GO:0007098]; chordate embryonic development [GO:0043009]; chromosome segregation [GO:0007059]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; fatty acid biosynthetic process [GO:0006633]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of centriole replication [GO:0046600]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of DNA repair [GO:0045739]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of histone H4-K20 methylation [GO:0070512]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; response to estrogen [GO:0043627]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	cytoplasm [GO:0005737]; DNA ligase III-XRCC1 complex [GO:0070421]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; gamma-tubulin ring complex [GO:0008274]; lateral element [GO:0000800]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA ligase (ATP) activity [GO:0003910]; DNA ligase activity [GO:0003909]; zinc ion binding [GO:0008270]	androgen receptor binding [GO:0050681]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1impa__d4uhpb___1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	protein-containing complex [GO:0032991]		protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	toxic substance binding [GO:0015643]
d1in0b2_d1in0a1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; nucleotide binding [GO:0000166]			cytosol [GO:0005829]	cytosol [GO:0005829]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d1indh1_d1ieaa1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]		
d1ineh1_d3bgfc1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ineh2_d5yaxa1__1						integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]		caveolin-mediated endocytosis of virus by host cell [GO:0075513]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]		integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		
d1inel1_d5ob5l2__1		Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; chemokine activity [GO:0008009]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; neutrophil chemotaxis [GO:0030593]; response to molecule of bacterial origin [GO:0002237]		antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; neutrophil chemotaxis [GO:0030593]; response to molecule of bacterial origin [GO:0002237]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		chemokine activity [GO:0008009]
d1inel2_d5k9jl1__1												
d1infa__d4yw5a2__1			Negarnaviricota	Firmicutes	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1inga__d5humc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1ingb__d1ncan___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1ingb__d2htra___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1inha__d4hzya1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1inqb__d1h3ta1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1inua__d3g3va___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1inwa__d3cyea___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1inxa__d3k37b___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1inya__d3k38f___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1inza__d1mhqa___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; lipid binding [GO:0008289]; embryonic organ development [GO:0048568]; endocytosis [GO:0006897]; female pregnancy [GO:0007565]; in utero embryonic development [GO:0001701]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of sprouting angiogenesis [GO:1903671]; Notch signaling pathway [GO:0007219]	clathrin-coated vesicle [GO:0030136]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; trans-Golgi network [GO:0005802]; ADP-ribosylation factor binding [GO:0030306]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; protein localization to cell surface [GO:0034394]	embryonic organ development [GO:0048568]; endocytosis [GO:0006897]; female pregnancy [GO:0007565]; in utero embryonic development [GO:0001701]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of sprouting angiogenesis [GO:1903671]; Notch signaling pathway [GO:0007219]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; protein localization to cell surface [GO:0034394]	clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	clathrin-coated vesicle [GO:0030136]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; trans-Golgi network [GO:0005802]	lipid binding [GO:0008289]	ADP-ribosylation factor binding [GO:0030306]
d1io0a__d1k5dl___1	Metazoa	Metazoa	Chordata	Chordata	costamere [GO:0043034]; sarcolemma [GO:0042383]; sarcomere [GO:0030017]; actin filament binding [GO:0051015]; metal ion binding [GO:0046872]; tropomyosin binding [GO:0005523]; pointed-end actin filament capping [GO:0051694]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	pointed-end actin filament capping [GO:0051694]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	costamere [GO:0043034]; sarcolemma [GO:0042383]; sarcomere [GO:0030017]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	actin filament binding [GO:0051015]; metal ion binding [GO:0046872]; tropomyosin binding [GO:0005523]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1io4c__d4ibuc___1	Metazoa	Metazoa	Chordata	Chordata	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1io5a__d2cjlb___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	chitinase activity [GO:0004568]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	chitinase activity [GO:0004568]; metal ion binding [GO:0046872]
d1io8a__d3a4ze___1			Crenarchaeota	Actinobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1io9a__d4kkyx___1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1ioaa__d1loa.1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; nutrient reservoir activity [GO:0045735]; toxin activity [GO:0090729]; defense response [GO:0006952]	mannose binding [GO:0005537]	defense response [GO:0006952]				carbohydrate binding [GO:0030246]; nutrient reservoir activity [GO:0045735]; toxin activity [GO:0090729]	mannose binding [GO:0005537]
d1iofa__d1ioib___1			Euryarchaeota	Euryarchaeota	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d1iofd__d3rnzd___1			Euryarchaeota	Firmicutes	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d1ioic__d4hpsb1__1			Euryarchaeota	Proteobacteria	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d1ioid__d1iofc___1			Euryarchaeota	Euryarchaeota	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d1ioma__d1nxga___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]	cytosol [GO:0005829]; citrate (Si)-synthase activity [GO:0004108]; identical protein binding [GO:0042802]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]	citrate (Si)-synthase activity [GO:0004108]; identical protein binding [GO:0042802]
d1iooa__d1j1fa1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular space [GO:0005615]; lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]			extracellular space [GO:0005615]		lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]
d1iopa__d1s61a___1	Metazoa		Chordata	Actinobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1ioqa__d199la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1iosa__d3e3da___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ip1a__d4ekpb1__1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ip3a__d3lyoa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ip5a__d4ow1e___1	Metazoa		Chordata	Actinobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	hydrolase activity [GO:0016787]
d1ipea__d4g81c___1	Viridiplantae		Streptophyta		tropinone reductase activity [GO:0050358]; tropane alkaloid biosynthetic process [GO:0009710]		tropane alkaloid biosynthetic process [GO:0009710]				tropinone reductase activity [GO:0050358]	
d1ipia__d1avqb___1			Euryarchaeota		crossover junction endodeoxyribonuclease activity [GO:0008821]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]	exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]				crossover junction endodeoxyribonuclease activity [GO:0008821]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]	exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]
d1ipjb1_d4zu7e1__1	Viridiplantae		Streptophyta	Firmicutes	aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]				aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]		nutrient reservoir activity [GO:0045735]	
d1ipka1_d2b9ub___1	Viridiplantae		Streptophyta	Crenarchaeota	aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]		dTDP-rhamnose biosynthetic process [GO:0019305]	aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]		nutrient reservoir activity [GO:0045735]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d1ipsa__d1gy9a___1	Fungi		Ascomycota	Proteobacteria	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]; penicillin biosynthetic process [GO:0042318]	cytoplasm [GO:0005737]; L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]; sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]	penicillin biosynthetic process [GO:0042318]	sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]		cytoplasm [GO:0005737]	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]	L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]
d1ipsb__d1qjfa___1	Fungi	Fungi	Ascomycota	Ascomycota	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]; penicillin biosynthetic process [GO:0042318]	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]; penicillin biosynthetic process [GO:0042318]	penicillin biosynthetic process [GO:0042318]	penicillin biosynthetic process [GO:0042318]			dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]
d1iq6a__d2bi0a2__1			Proteobacteria	Actinobacteria	fatty acid synthase complex [GO:0005835]; fatty acid synthase activity [GO:0004312]; lyase activity [GO:0016829]; fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114]	plasma membrane [GO:0005886]	fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114]		fatty acid synthase complex [GO:0005835]	plasma membrane [GO:0005886]	fatty acid synthase activity [GO:0004312]; lyase activity [GO:0016829]	
d1iq8a3_d2apoa1__1			Euryarchaeota	Euryarchaeota	metal ion binding [GO:0046872]; RNA binding [GO:0003723]; transferase activity, transferring pentosyl groups [GO:0016763]; tRNA modification [GO:0006400]	box H/ACA snoRNP complex [GO:0031429]; pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]; box H/ACA snoRNA 3'-end processing [GO:0000495]; mRNA pseudouridine synthesis [GO:1990481]; rRNA pseudouridine synthesis [GO:0031118]; snRNA pseudouridine synthesis [GO:0031120]; tRNA pseudouridine synthesis [GO:0031119]	tRNA modification [GO:0006400]	box H/ACA snoRNA 3'-end processing [GO:0000495]; mRNA pseudouridine synthesis [GO:1990481]; rRNA pseudouridine synthesis [GO:0031118]; snRNA pseudouridine synthesis [GO:0031120]; tRNA pseudouridine synthesis [GO:0031119]		box H/ACA snoRNP complex [GO:0031429]	metal ion binding [GO:0046872]; RNA binding [GO:0003723]; transferase activity, transferring pentosyl groups [GO:0016763]	pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]
d1iqca2_d1nnoa1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1iqcb1_d1ynra___1			Proteobacteria	Aquificae	periplasmic space [GO:0042597]; cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]		cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1iqdb1_d1jufa1__1	Metazoa	Metazoa	Chordata	Chordata	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1iqdc__d2pqsb1__1	Metazoa	Metazoa	Chordata	Chordata	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	extracellular region [GO:0005576]; membrane [GO:0016020]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	extracellular region [GO:0005576]; membrane [GO:0016020]	copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]	
d1iqka__d2z9lb___1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1iqla__d1p09a___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1iqma__d5dk1a1__1	Metazoa		Chordata	Actinobacteria	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	serine-type endopeptidase activity [GO:0004252]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1iqna__d3vfea___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]; serine-type endopeptidase activity [GO:0004252]; amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1iqpa1_d1xxic1__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA-dependent DNA replication [GO:0006261]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	DNA-dependent DNA replication [GO:0006261]		DNA polymerase III complex [GO:0009360]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1iqpa2_d1z0fa___1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; rough endoplasmic reticulum [GO:0005791]; tertiary granule membrane [GO:0070821]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin V binding [GO:0031489]; defense response to bacterium [GO:0042742]; endocytic recycling [GO:0032456]; fibroblast growth factor receptor signaling pathway [GO:0008543]; Golgi to endosome transport [GO:0006895]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; neutrophil degranulation [GO:0043312]; phagolysosome assembly involved in apoptotic cell clearance [GO:0090387]; phosphatidylinositol biosynthetic process [GO:0006661]; Rab protein signal transduction [GO:0032482]; regulation of embryonic development [GO:0045995]; regulation of protein localization [GO:0032880]; vesicle-mediated transport [GO:0016192]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	defense response to bacterium [GO:0042742]; endocytic recycling [GO:0032456]; fibroblast growth factor receptor signaling pathway [GO:0008543]; Golgi to endosome transport [GO:0006895]; intracellular protein transport [GO:0006886]; intracellular transport [GO:0046907]; neutrophil degranulation [GO:0043312]; phagolysosome assembly involved in apoptotic cell clearance [GO:0090387]; phosphatidylinositol biosynthetic process [GO:0006661]; Rab protein signal transduction [GO:0032482]; regulation of embryonic development [GO:0045995]; regulation of protein localization [GO:0032880]; vesicle-mediated transport [GO:0016192]		cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; rough endoplasmic reticulum [GO:0005791]; tertiary granule membrane [GO:0070821]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin V binding [GO:0031489]
d1iqpb1_d1xxij1__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA-dependent DNA replication [GO:0006261]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	DNA-dependent DNA replication [GO:0006261]		DNA polymerase III complex [GO:0009360]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1iqpd1_d1jr3a1__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA-dependent DNA replication [GO:0006261]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	DNA-dependent DNA replication [GO:0006261]		DNA polymerase III complex [GO:0009360]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1iqqa__d1v9ha1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]					lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]
d1iqqa__d3d3za___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]					lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]
d1iqra2_d3cvya1__1		Metazoa	Deinococcus-Thermus	Arthropoda	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	nucleotide binding [GO:0000166]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]				deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d1iqta__d2cq4a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202]; AT DNA binding [GO:0003680]; chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; telomeric DNA binding [GO:0042162]; transcription factor binding [GO:0008134]; 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of telomerase RNA reverse transcriptase activity [GO:1905663]; positive regulation of telomere capping [GO:1904355]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of mRNA stability [GO:0043488]; regulation of telomere maintenance [GO:0032204]; regulation of transcription, DNA-templated [GO:0006355]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; RNA catabolic process [GO:0006401]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA binding [GO:0003723]; mRNA processing [GO:0006397]	3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of telomerase RNA reverse transcriptase activity [GO:1905663]; positive regulation of telomere capping [GO:1904355]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of mRNA stability [GO:0043488]; regulation of telomere maintenance [GO:0032204]; regulation of transcription, DNA-templated [GO:0006355]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; RNA catabolic process [GO:0006401]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	mRNA processing [GO:0006397]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202]	membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	AT DNA binding [GO:0003680]; chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; telomeric DNA binding [GO:0042162]; transcription factor binding [GO:0008134]	RNA binding [GO:0003723]
d1iqta__d2n3la1__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202]; AT DNA binding [GO:0003680]; chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; telomeric DNA binding [GO:0042162]; transcription factor binding [GO:0008134]; 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of telomerase RNA reverse transcriptase activity [GO:1905663]; positive regulation of telomere capping [GO:1904355]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of mRNA stability [GO:0043488]; regulation of telomere maintenance [GO:0032204]; regulation of transcription, DNA-templated [GO:0006355]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; RNA catabolic process [GO:0006401]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; RNA binding [GO:0003723]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of telomerase RNA reverse transcriptase activity [GO:1905663]; positive regulation of telomere capping [GO:1904355]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of mRNA stability [GO:0043488]; regulation of telomere maintenance [GO:0032204]; regulation of transcription, DNA-templated [GO:0006355]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; RNA catabolic process [GO:0006401]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	mRNA cis splicing, via spliceosome [GO:0045292]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]	AT DNA binding [GO:0003680]; chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; telomeric DNA binding [GO:0042162]; transcription factor binding [GO:0008134]	RNA binding [GO:0003723]
d1iqwh1_d3nn8d1__1												
d1iqwl1_d1smoa___1		Metazoa		Chordata		extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]; acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]		acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]
d1ir1a2_d5haob1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1ir2j__d2vdhn___1	Viridiplantae	Viridiplantae	Chlorophyta	Chlorophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1ir2o__d3axms___1	Viridiplantae	Viridiplantae	Chlorophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1ir2o__d5iu0j___1	Viridiplantae	Viridiplantae	Chlorophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast membrane [GO:0031969]; chloroplast stroma [GO:0009570]; plastid [GO:0009536]; thylakoid [GO:0009579]; monooxygenase activity [GO:0004497]; protein domain specific binding [GO:0019904]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]; response to blue light [GO:0009637]; response to far red light [GO:0010218]; response to red light [GO:0010114]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]; response to blue light [GO:0009637]; response to far red light [GO:0010218]; response to red light [GO:0010114]	chloroplast [GO:0009507]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast membrane [GO:0031969]; chloroplast stroma [GO:0009570]; plastid [GO:0009536]; thylakoid [GO:0009579]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; protein domain specific binding [GO:0019904]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1ir2p__d2vdij___1	Viridiplantae	Viridiplantae	Chlorophyta	Chlorophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1ir7a__d5v92b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ir8a__d1f6rc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]
d1iray2_d5x2mk1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; G protein-coupled receptor activity [GO:0004930]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]	G protein-coupled receptor activity [GO:0004930]
d1irda__d1lfzb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1irib__d2zj4a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; circadian regulation of gene expression [GO:0032922]; energy reserve metabolic process [GO:0006112]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; IRE1-mediated unfolded protein response [GO:0036498]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	circadian regulation of gene expression [GO:0032922]; energy reserve metabolic process [GO:0006112]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; IRE1-mediated unfolded protein response [GO:0036498]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]
d1irid__d5lu5b___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]
d1irja__d1kfus___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d1irjb__d1yutb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d1irjc__d3bxla___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]	antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]
d1irje__d1spya___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]	antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]
d1irjh__d2k2fb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	A band [GO:0031672]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; I band [GO:0031674]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	A band [GO:0031672]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; I band [GO:0031674]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]
d1irma__d4ny7b1__1	Metazoa		Chordata	Proteobacteria	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	pyrroloquinoline-quinone synthase activity [GO:0033732]; pyrroloquinoline quinone biosynthetic process [GO:0018189]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	pyrroloquinoline quinone biosynthetic process [GO:0018189]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]		enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	pyrroloquinoline-quinone synthase activity [GO:0033732]
d1irpa__d3bava1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; interleukin-1 type I receptor antagonist activity [GO:0045352]; interleukin-1 type II receptor antagonist activity [GO:0045353]; interleukin-1, type I receptor binding [GO:0005150]; interleukin-1, type II receptor binding [GO:0005151]; acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; interleukin-1-mediated signaling pathway [GO:0070498]; lipid metabolic process [GO:0006629]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; response to glucocorticoid [GO:0051384]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; interleukin-1-mediated signaling pathway [GO:0070498]; lipid metabolic process [GO:0006629]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; response to glucocorticoid [GO:0051384]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytokine activity [GO:0005125]; interleukin-1, type II receptor binding [GO:0005151]; interleukin-1, type I receptor binding [GO:0005150]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; interleukin-1 type II receptor antagonist activity [GO:0045353]; interleukin-1 type I receptor antagonist activity [GO:0045352]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1iru1__d4qw7t___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1irub__d5d0tk___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1iruf__d5bouo___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1iruf__d5l61q___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1irug__d2gpll___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1iruj__d5fgft___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1irul__d4qwgb___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1irut__d4qwrn___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1irux__d4qz3q___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1irux__d5l5yk___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1is2a1_d4l1fa2__1	Metazoa		Chordata	Firmicutes	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; palmitoyl-CoA oxidase activity [GO:0016401]; protein homodimerization activity [GO:0042803]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693]; very long-chain fatty acid metabolic process [GO:0000038]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693]; very long-chain fatty acid metabolic process [GO:0000038]		peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; palmitoyl-CoA oxidase activity [GO:0016401]; protein homodimerization activity [GO:0042803]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d1is4a__d3galb___1	Metazoa	Metazoa	Chordata	Chordata	carbohydrate binding [GO:0030246]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d1is5a__d3wvjb___1	Metazoa		Chordata	Firmicutes	carbohydrate binding [GO:0030246]	licheninase activity [GO:0042972]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]	licheninase activity [GO:0042972]
d1is6a__d3lcpa___1	Metazoa	Metazoa	Chordata	Chordata	carbohydrate binding [GO:0030246]	endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; calcium ion binding [GO:0005509]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]		COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]		endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]	carbohydrate binding [GO:0030246]	calcium ion binding [GO:0005509]
d1is7a__d1j2gd1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]; allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]
d1is7b__d2o9mc___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]		negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]	
d1is7c__d1n3sd___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1is7c__d5ll1c1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]	urate oxidase activity [GO:0004846]
d1is7i__d1n3ri___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1is7j__d1n3tm___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1isaa1_d2bkbc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]
d1isaa1_d2rcve1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1isab1_d1dt0c1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1isab2_d3js4d2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1isba1_d3tqjb1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1isbb1_d1mnga1__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1isbb1_d5tirc1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1isbb2_d4jzga2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1isca1_d2cw3a1__1			Proteobacteria	Perkinsozoa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	integral component of membrane [GO:0016021]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1iscb1_d1uerc1__1			Proteobacteria	Bacteroidetes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1isfa__d3zwwb1__1	Metazoa	Metazoa	Chordata	Mollusca	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]; ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]	cytoplasmic vesicle [GO:0031410]	ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]
d1isga__d3zwph___1	Metazoa	Metazoa	Chordata	Mollusca	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]; ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]	cytoplasmic vesicle [GO:0031410]	ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]
d1isia__d2pgja___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]; ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d1isia__d5bnfb___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]; ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]; positive regulation of B cell proliferation [GO:0030890]	humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	positive regulation of B cell proliferation [GO:0030890]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]
d1isna2_d1mk9d2__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]
d1isqa1_d4k3la3__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; DNA clamp loader activity [GO:0003689]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	ATP binding [GO:0005524]; DNA clamp loader activity [GO:0003689]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1isqa2_d4mjpb3__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; DNA clamp loader activity [GO:0003689]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	ATP binding [GO:0005524]; DNA clamp loader activity [GO:0003689]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1istb__d3rcfa___1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; Set3 complex [GO:0034967]; cyclosporin A binding [GO:0016018]; mRNA binding [GO:0003729]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; ascospore formation [GO:0030437]; cellular protein metabolic process [GO:0044267]; histone deacetylation [GO:0016575]; positive regulation of meiotic nuclear division [GO:0045836]; protein refolding [GO:0042026]; protein transport [GO:0015031]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	ascospore formation [GO:0030437]; cellular protein metabolic process [GO:0044267]; histone deacetylation [GO:0016575]; positive regulation of meiotic nuclear division [GO:0045836]; protein refolding [GO:0042026]; protein transport [GO:0015031]	apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; Set3 complex [GO:0034967]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]	cyclosporin A binding [GO:0016018]; mRNA binding [GO:0003729]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]
d1isva1_d2z49a2__1		Metazoa	Actinobacteria	Echinodermata	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	polysaccharide catabolic process [GO:0000272]				endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1isva2_d3t09a3__1			Actinobacteria	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	endo-1,4-beta-xylanase activity [GO:0031176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1isvb1_d3ca3a2__1		Viridiplantae	Actinobacteria	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	polysaccharide catabolic process [GO:0000272]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1isvb2_d1f4hd5__1			Actinobacteria	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	endo-1,4-beta-xylanase activity [GO:0031176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1isvb2_d1zs2a2__1			Actinobacteria	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	amylosucrase activity [GO:0047669]
d1iswa1_d4lo3a1__1			Actinobacteria	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]				endo-1,4-beta-xylanase activity [GO:0031176]	
d1isxa1_d3ah1a1__1			Actinobacteria		endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]	polysaccharide catabolic process [GO:0000272]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]
d1isxa1_d4lo1a1__1			Actinobacteria	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]				endo-1,4-beta-xylanase activity [GO:0031176]	
d1isxa2_d1qhoa4__1			Actinobacteria	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1isxb2_d1y7va2__1		Metazoa	Actinobacteria	Chordata	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	polysaccharide catabolic process [GO:0000272]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	endo-1,4-beta-xylanase activity [GO:0031176]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1isza2_d1fhda___1			Actinobacteria	Actinobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]
d1it0a2_d1uwib___1			Actinobacteria	Crenarchaeota	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]
d1it0b1_d1dqga___1		Metazoa	Actinobacteria	Chordata	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	cell surface [GO:0009986]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cargo receptor activity [GO:0038024]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	polysaccharide catabolic process [GO:0000272]	cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]		cell surface [GO:0009986]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	endo-1,4-beta-xylanase activity [GO:0031176]	cargo receptor activity [GO:0038024]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]
d1it3b__d4hsxa___1	Metazoa	Metazoa	Chordata	Annelida	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d1it6a__d4hd0a___1	Metazoa		Chordata	Euryarchaeota	cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; protein-containing complex [GO:0032991]; PTW/PP1 phosphatase complex [GO:0072357]; lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]	3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]; double-strand break repair [GO:0006302]	cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]	double-strand break repair [GO:0006302]	cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]		lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]	3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]
d1it9h2_d1ggij2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1it9h2_d2yd1a1__1		Metazoa		Arthropoda		axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]		axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]		axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]		heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d1it9l1_d4kkna___1		Metazoa		Chordata		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of regulatory T cell differentiation [GO:0045590]; positive regulation of apoptotic process [GO:0043065]; regulation of T cell proliferation [GO:0042129]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of regulatory T cell differentiation [GO:0045590]; positive regulation of apoptotic process [GO:0043065]; regulation of T cell proliferation [GO:0042129]; T cell receptor signaling pathway [GO:0050852]		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]		
d1itbb1_d2vitb1__1	Metazoa		Chordata	Negarnaviricota	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]	host cell surface receptor binding [GO:0046789]
d1itbb2_d3ojmb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1itkb1_d1mhl.2__1		Metazoa	Euryarchaeota	Chordata	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]; chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]		azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1itub__d4qs5a___1	Metazoa		Chordata	Proteobacteria	anchored component of membrane [GO:0031225]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; dipeptidyl-peptidase activity [GO:0008239]; GPI anchor binding [GO:0034235]; metallodipeptidase activity [GO:0070573]; metalloexopeptidase activity [GO:0008235]; modified amino acid binding [GO:0072341]; zinc ion binding [GO:0008270]; antibiotic metabolic process [GO:0016999]; cellular lactam catabolic process [GO:0072340]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; cellular response to nitric oxide [GO:0071732]; glutathione metabolic process [GO:0006749]; homocysteine metabolic process [GO:0050667]; leukotriene metabolic process [GO:0006691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; xenobiotic metabolic process [GO:0006805]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	antibiotic metabolic process [GO:0016999]; cellular lactam catabolic process [GO:0072340]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; cellular response to nitric oxide [GO:0071732]; glutathione metabolic process [GO:0006749]; homocysteine metabolic process [GO:0050667]; leukotriene metabolic process [GO:0006691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; xenobiotic metabolic process [GO:0006805]		anchored component of membrane [GO:0031225]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; dipeptidyl-peptidase activity [GO:0008239]; GPI anchor binding [GO:0034235]; metallodipeptidase activity [GO:0070573]; metalloexopeptidase activity [GO:0008235]; modified amino acid binding [GO:0072341]; zinc ion binding [GO:0008270]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1itvb__d1su3b2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1itwd__d1t0lb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; 2-oxoglutarate metabolic process [GO:0006103]; female gonad development [GO:0008585]; glutathione metabolic process [GO:0006749]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; NADPH regeneration [GO:0006740]; neutrophil degranulation [GO:0043312]; protein targeting to peroxisome [GO:0006625]; regulation of phospholipid biosynthetic process [GO:0071071]; regulation of phospholipid catabolic process [GO:0060696]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; tricarboxylic acid cycle [GO:0006099]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	2-oxoglutarate metabolic process [GO:0006103]; female gonad development [GO:0008585]; glutathione metabolic process [GO:0006749]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADPH regeneration [GO:0006740]; NADP metabolic process [GO:0006739]; neutrophil degranulation [GO:0043312]; protein targeting to peroxisome [GO:0006625]; regulation of phospholipid biosynthetic process [GO:0071071]; regulation of phospholipid catabolic process [GO:0060696]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]
d1itza1_d1ovmb2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; auxin biosynthetic process [GO:0009851]	pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	auxin biosynthetic process [GO:0009851]	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]		calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1itza2_d1trkb1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	pentose-phosphate shunt [GO:0006098]	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1itzb3_d1umbb2__1	Viridiplantae		Streptophyta	Deinococcus-Thermus	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]		calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]
d1itzc3_d2bp7h2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]	pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]		calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]
d1iu0a__d3stja2__1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]
d1iu2a__d2vspb___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]; carnitine transport [GO:0015879]; cell population proliferation [GO:0008283]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of anion transport [GO:0044070]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	carnitine transport [GO:0015879]; cell population proliferation [GO:0008283]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of anion transport [GO:0044070]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]	PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]
d1iuea1_d1krha3__1			Apicomplexa	Proteobacteria	apicoplast [GO:0020011]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]; toluene catabolic process [GO:0042203]	oxidation-reduction process [GO:0055114]	toluene catabolic process [GO:0042203]	apicoplast [GO:0020011]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]
d1iuea1_d3w9cb___1			Apicomplexa	Proteobacteria	apicoplast [GO:0020011]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]	apicoplast [GO:0020011]	cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1iueb1_d2piaa3__1			Apicomplexa	Proteobacteria	apicoplast [GO:0020011]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	oxidation-reduction process [GO:0055114]		apicoplast [GO:0020011]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1iupa__d3v1ma___1			Proteobacteria	Proteobacteria	hydrolase activity [GO:0016787]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			hydrolase activity [GO:0016787]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]
d1iuwa2_d1s2ya2__1		Metazoa	Proteobacteria	Chordata	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1iuxa2_d2bk3a2__1		Metazoa	Proteobacteria	Chordata	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1iv1b__d3jvha___1			Deinococcus-Thermus	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d1iv2b__d1h47e1__1			Deinococcus-Thermus	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d1iv3a__d3erne1__1			Deinococcus-Thermus	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d1iv3f__d5iwyb___1			Deinococcus-Thermus	Firmicutes	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d1iv4a__d3f0fa___1			Deinococcus-Thermus	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d1iv8a1_d3a6ob2__1			Crenarchaeota	Firmicutes	catalytic activity [GO:0003824]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			catalytic activity [GO:0003824]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1ivba__d3tica___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1ivcb__d3ticb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1ivdb__d4b7na___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1ivea__d2ht5a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1ivfa__d1v3ea___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d1ivfb__d2hu4c___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1ivga__d4gezb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1ivgb__d3b7ea___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1ivhc1_d3mdda1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; isovaleryl-CoA dehydrogenase activity [GO:0008470]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552]	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]	mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; isovaleryl-CoA dehydrogenase activity [GO:0008470]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]
d1ivma__d2meaa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; Golgi cis cisterna [GO:0000137]; Golgi stack [GO:0005795]; microvillus [GO:0005902]; rough endoplasmic reticulum lumen [GO:0048237]; secretory granule [GO:0030141]; trans-Golgi network transport vesicle [GO:0030140]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; Golgi cis cisterna [GO:0000137]; Golgi stack [GO:0005795]; microvillus [GO:0005902]; rough endoplasmic reticulum lumen [GO:0048237]; secretory granule [GO:0030141]; trans-Golgi network transport vesicle [GO:0030140]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ivoa2_d2v70c___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated vesicle membrane [GO:0030665]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; receptor complex [GO:0043235]; calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; growth factor activity [GO:0008083]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; canonical Wnt signaling pathway [GO:0060070]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; ERK1 and ERK2 cascade [GO:0070371]; mammary gland alveolus development [GO:0060749]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of secretion [GO:0051048]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet degranulation [GO:0002576]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of gene expression [GO:0010628]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of calcium ion import [GO:0090279]; regulation of cell motility [GO:2000145]; regulation of protein localization to cell surface [GO:2000008]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; signal transduction [GO:0007165]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; GTPase inhibitor activity [GO:0005095]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; laminin-1 binding [GO:0043237]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; Roundabout binding [GO:0048495]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; cellular response to hormone stimulus [GO:0032870]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; induction of negative chemotaxis [GO:0050929]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; pulmonary valve morphogenesis [GO:0003184]; response to cortisol [GO:0051414]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; canonical Wnt signaling pathway [GO:0060070]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; ERK1 and ERK2 cascade [GO:0070371]; mammary gland alveolus development [GO:0060749]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of secretion [GO:0051048]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet degranulation [GO:0002576]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of gene expression [GO:0010628]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of calcium ion import [GO:0090279]; regulation of cell motility [GO:2000145]; regulation of protein localization to cell surface [GO:2000008]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; signal transduction [GO:0007165]	aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; cellular response to hormone stimulus [GO:0032870]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; induction of negative chemotaxis [GO:0050929]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; pulmonary valve morphogenesis [GO:0003184]; response to cortisol [GO:0051414]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	clathrin-coated vesicle membrane [GO:0030665]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; receptor complex [GO:0043235]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; growth factor activity [GO:0008083]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]	calcium ion binding [GO:0005509]; GTPase inhibitor activity [GO:0005095]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; laminin-1 binding [GO:0043237]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; Roundabout binding [GO:0048495]
d1ivob1_d1moxb2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated vesicle membrane [GO:0030665]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; receptor complex [GO:0043235]; calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; growth factor activity [GO:0008083]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; canonical Wnt signaling pathway [GO:0060070]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; ERK1 and ERK2 cascade [GO:0070371]; mammary gland alveolus development [GO:0060749]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of secretion [GO:0051048]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet degranulation [GO:0002576]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of gene expression [GO:0010628]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of calcium ion import [GO:0090279]; regulation of cell motility [GO:2000145]; regulation of protein localization to cell surface [GO:2000008]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; canonical Wnt signaling pathway [GO:0060070]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; ERK1 and ERK2 cascade [GO:0070371]; mammary gland alveolus development [GO:0060749]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of secretion [GO:0051048]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet degranulation [GO:0002576]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of gene expression [GO:0010628]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of calcium ion import [GO:0090279]; regulation of cell motility [GO:2000145]; regulation of protein localization to cell surface [GO:2000008]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; signal transduction [GO:0007165]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	clathrin-coated vesicle membrane [GO:0030665]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; receptor complex [GO:0043235]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; growth factor activity [GO:0008083]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d1ivob2_d2v70d___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated vesicle membrane [GO:0030665]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; receptor complex [GO:0043235]; calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; growth factor activity [GO:0008083]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; canonical Wnt signaling pathway [GO:0060070]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; ERK1 and ERK2 cascade [GO:0070371]; mammary gland alveolus development [GO:0060749]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of secretion [GO:0051048]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet degranulation [GO:0002576]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of gene expression [GO:0010628]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of calcium ion import [GO:0090279]; regulation of cell motility [GO:2000145]; regulation of protein localization to cell surface [GO:2000008]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; signal transduction [GO:0007165]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; GTPase inhibitor activity [GO:0005095]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; laminin-1 binding [GO:0043237]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; Roundabout binding [GO:0048495]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; cellular response to hormone stimulus [GO:0032870]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; induction of negative chemotaxis [GO:0050929]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; pulmonary valve morphogenesis [GO:0003184]; response to cortisol [GO:0051414]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; canonical Wnt signaling pathway [GO:0060070]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; ERK1 and ERK2 cascade [GO:0070371]; mammary gland alveolus development [GO:0060749]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of secretion [GO:0051048]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet degranulation [GO:0002576]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of gene expression [GO:0010628]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of calcium ion import [GO:0090279]; regulation of cell motility [GO:2000145]; regulation of protein localization to cell surface [GO:2000008]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; signal transduction [GO:0007165]	aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; cellular response to hormone stimulus [GO:0032870]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; induction of negative chemotaxis [GO:0050929]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; pulmonary valve morphogenesis [GO:0003184]; response to cortisol [GO:0051414]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	clathrin-coated vesicle membrane [GO:0030665]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; receptor complex [GO:0043235]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; growth factor activity [GO:0008083]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]	calcium ion binding [GO:0005509]; GTPase inhibitor activity [GO:0005095]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; laminin-1 binding [GO:0043237]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; Roundabout binding [GO:0048495]
d1ivqa__d4mc6a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ivqb__d2weca___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1ivra__d1g4va___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1ivsb2_d4mw7b2__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; valine-tRNA ligase activity [GO:0004832]; valyl-tRNA aminoacylation [GO:0006438]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	valyl-tRNA aminoacylation [GO:0006438]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; valine-tRNA ligase activity [GO:0004832]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]
d1ivta__d3hn9c___1	Metazoa		Chordata		cytosol [GO:0005829]; intermediate filament [GO:0005882]; lamin filament [GO:0005638]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear lamina [GO:0005652]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; cellular protein localization [GO:0034613]; cellular response to hypoxia [GO:0071456]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; IRE1-mediated unfolded protein response [GO:0036498]; mitotic nuclear envelope reassembly [GO:0007084]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of mesenchymal cell proliferation [GO:0072201]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; nuclear envelope organization [GO:0006998]; positive regulation of cell aging [GO:0090343]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K9 trimethylation [GO:1900114]; protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504]; regulation of cell migration [GO:0030334]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; ventricular cardiac muscle cell development [GO:0055015]		cellular protein localization [GO:0034613]; cellular response to hypoxia [GO:0071456]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; IRE1-mediated unfolded protein response [GO:0036498]; mitotic nuclear envelope reassembly [GO:0007084]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of mesenchymal cell proliferation [GO:0072201]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; nuclear envelope organization [GO:0006998]; positive regulation of cell aging [GO:0090343]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K9 trimethylation [GO:1900114]; protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504]; regulation of cell migration [GO:0030334]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; ventricular cardiac muscle cell development [GO:0055015]		cytosol [GO:0005829]; intermediate filament [GO:0005882]; lamin filament [GO:0005638]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear lamina [GO:0005652]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	
d1ivya__d3vjkb2__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; membrane [GO:0016020]; carboxypeptidase activity [GO:0004180]; enzyme activator activity [GO:0008047]; serine-type carboxypeptidase activity [GO:0004185]; glycosphingolipid metabolic process [GO:0006687]; intracellular protein transport [GO:0006886]; negative regulation of chaperone-mediated autophagy [GO:1904715]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of chaperone-mediated autophagy [GO:1904714]; regulation of protein stability [GO:0031647]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	glycosphingolipid metabolic process [GO:0006687]; intracellular protein transport [GO:0006886]; negative regulation of chaperone-mediated autophagy [GO:1904715]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of chaperone-mediated autophagy [GO:1904714]; regulation of protein stability [GO:0031647]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	azurophil granule lumen [GO:0035578]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; membrane [GO:0016020]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	carboxypeptidase activity [GO:0004180]; enzyme activator activity [GO:0008047]; serine-type carboxypeptidase activity [GO:0004185]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1iw0c__d2gm7a1__1			Actinobacteria	Crenarchaeota	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	cytosol [GO:0005829]; thiaminase activity [GO:0050334]; thiamine metabolic process [GO:0006772]	heme oxidation [GO:0006788]	thiamine metabolic process [GO:0006772]		cytosol [GO:0005829]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	thiaminase activity [GO:0050334]
d1iwac2_d1bxng2__1			Rhodophyta	Proteobacteria	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]		reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]			magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1iwae1_d1rbol1__1		Viridiplantae	Rhodophyta	Streptophyta	chloroplast [GO:0009507]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]		magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1iwaf__d2v68n___1		Viridiplantae	Rhodophyta	Chlorophyta	chloroplast [GO:0009507]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]		magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1iwak2_d5hqla1__1			Rhodophyta	Proteobacteria	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]		reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]			magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1iwam2_d5hjya1__1			Rhodophyta	Proteobacteria	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]		reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]			magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1iwan__d2v6al___1		Viridiplantae	Rhodophyta	Chlorophyta	chloroplast [GO:0009507]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]		magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1iwbb__d2d0ob1__1			Proteobacteria	Proteobacteria	propanediol dehydratase activity [GO:0050215]						propanediol dehydratase activity [GO:0050215]	
d1iwda__d2p0ra___1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]	cytoplasm [GO:0005737]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; digestion [GO:0007586]; sarcomere organization [GO:0045214]		digestion [GO:0007586]; sarcomere organization [GO:0045214]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	cysteine-type peptidase activity [GO:0008234]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d1iwia__d2pg5c___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d1iwka__d3a50d___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1iwpb__d1nbwd___1			Proteobacteria	Proteobacteria	cobalamin binding [GO:0031419]; glycerol dehydratase activity [GO:0046405]	ATP binding [GO:0005524]; glycerol dehydratase activity [GO:0046405]; metal ion binding [GO:0046872]					cobalamin binding [GO:0031419]; glycerol dehydratase activity [GO:0046405]	ATP binding [GO:0005524]; glycerol dehydratase activity [GO:0046405]; metal ion binding [GO:0046872]
d1iwua__d1fbiy___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1iwua__d2huka___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1iwwa__d1jita___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1iwxa__d1b5xa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1iwya__d1t8fa___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1iwza__d3ht8a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ix0a__d4e3ua___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ix4a__d1oykb___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1ix5a__d4drhd___1		Metazoa	Euryarchaeota	Chordata	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]		chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1ix6a__d5vwqa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1ix9b2_d1msda2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ixba2_d2rcvc2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ixbb2_d1y67d2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ixga__d4nhbb1__1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	transmembrane transport [GO:0055085]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]		phosphate ion binding [GO:0042301]	
d1ixna__d3gk0f___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	cytoplasm [GO:0005737]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]	pyridoxine 5'-phosphate synthase activity [GO:0033856]
d1ixnb__d5dlca___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	cytoplasm [GO:0005737]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]	pyridoxine 5'-phosphate synthase activity [GO:0033856]
d1ixpa__d3f4nh___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	cytosol [GO:0005829]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	cytosol [GO:0005829]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]	pyridoxine 5'-phosphate synthase activity [GO:0033856]
d1ixpc__d1m5wa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	cytosol [GO:0005829]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]	identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]
d1ixra1_d2bhnd1__1			Deinococcus-Thermus	Crenarchaeota	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	DNA repair [GO:0006281]			ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d1ixrc2_d3b60d1__1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]	ATPase activity [GO:0016887]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]
d1ixrc2_d3hu2a3__1		Metazoa	Deinococcus-Thermus	Chordata	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1ixxa__d2kv3a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; heparin binding [GO:0008201]; mannan binding [GO:2001065]; transmembrane signaling receptor activity [GO:0004888]; response to bacterium [GO:0009617]		response to bacterium [GO:0009617]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	heparin binding [GO:0008201]; mannan binding [GO:2001065]; transmembrane signaling receptor activity [GO:0004888]
d1ixxb__d2ridb1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]		cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	extracellular region [GO:0005576]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1ixxc__d4n37a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]		antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	extracellular region [GO:0005576]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1ixyb__d4bqfb___1		Viridiplantae		Streptophyta	DNA beta-glucosyltransferase activity [GO:0033821]; DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]	chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; phosphorylase activity [GO:0004645]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]; glycogen catabolic process [GO:0005980]; response to cadmium ion [GO:0046686]; response to water deprivation [GO:0009414]	DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]	glycogen catabolic process [GO:0005980]; response to cadmium ion [GO:0046686]; response to water deprivation [GO:0009414]		chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	DNA beta-glucosyltransferase activity [GO:0033821]	glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; phosphorylase activity [GO:0004645]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]
d1iy8a__d2pd3c___1			Actinobacteria	Proteobacteria	oxidoreductase activity [GO:0016491]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]		fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]			oxidoreductase activity [GO:0016491]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]
d1iy8b__d5k4ua1__1			Actinobacteria		oxidoreductase activity [GO:0016491]	coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]					oxidoreductase activity [GO:0016491]	coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]
d1iy8d__d3ausb1__1			Actinobacteria	Firmicutes	oxidoreductase activity [GO:0016491]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; identical protein binding [GO:0042802]					oxidoreductase activity [GO:0016491]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; identical protein binding [GO:0042802]
d1iy9c__d5k09u___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; spermidine biosynthetic process [GO:0008295]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	spermidine biosynthetic process [GO:0008295]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytosol [GO:0005829]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	spermidine synthase activity [GO:0004766]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d1iy9d__d2rhbb1__1			Firmicutes		cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; spermidine biosynthetic process [GO:0008295]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	spermidine biosynthetic process [GO:0008295]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	cytosol [GO:0005829]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	spermidine synthase activity [GO:0004766]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1iyba1_d1dixa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	cell wall [GO:0005618]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endoribonuclease activity [GO:0004521]; lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]; RNA catabolic process [GO:0006401]		RNA catabolic process [GO:0006401]		cell wall [GO:0005618]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]
d1iyha1_d2vcrh2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	
d1iyha2_d1u87a2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione transferase activity [GO:0004364]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d1iyha2_d3sbce___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]; identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]; cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]
d1iyhb1_d2dsad2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione transferase activity [GO:0004364]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d1iyhb2_d3ik9g1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1iyhd2_d20gsb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1iyic2_d2vctf1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d1iyid2_d1gh2a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; proteasome complex [GO:0000502]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	disulfide oxidoreductase activity [GO:0015036]
d1iyid2_d2pmtc2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d1iyjd5_d1n36l___1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; proteasome complex [GO:0000502]; proteasome regulatory particle, lid subcomplex [GO:0008541]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; mRNA export from nucleus [GO:0006406]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasome assembly [GO:0043248]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; mRNA export from nucleus [GO:0006406]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasome assembly [GO:0043248]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	translation [GO:0006412]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; proteasome complex [GO:0000502]; proteasome regulatory particle, lid subcomplex [GO:0008541]	ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1iyka2_d4ag9b___1	Fungi	Metazoa	Ascomycota	Nematoda (roundworms)	cytoplasm [GO:0005737]; drug binding [GO:0008144]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; pathogenesis [GO:0009405]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; pathogenesis [GO:0009405]	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]	drug binding [GO:0008144]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]	glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]
d1iylb1_d5vdba___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; drug binding [GO:0008144]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; pathogenesis [GO:0009405]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]	N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; pathogenesis [GO:0009405]		cytoplasm [GO:0005737]		drug binding [GO:0008144]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]
d1iyna__d5sx0b1__1	Viridiplantae		Streptophyta	Proteobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1iyxa1_d3ujea2__1		Metazoa	Firmicutes	Chordata	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1iyxa2_d3ucdb1__1		Metazoa	Firmicutes	Chordata	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1iyxb1_d2akzb1__1		Metazoa	Firmicutes	Chordata	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1iz1a2_d1qula___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]		cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	phosphate ion binding [GO:0042301]
d1iz1p2_d1d3ka___1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]		actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]		apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d1iz4a1_d1yypa1__1			Euryarchaeota		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	host cell nucleus [GO:0042025]; virion [GO:0019012]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]		host cell nucleus [GO:0042025]; virion [GO:0019012]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d1iz5a1_d3qsba1__1			Euryarchaeota	Proteobacteria	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1iz7a__d1hdea___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	response to toxic substance [GO:0009636]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	periplasmic space [GO:0042597]		haloalkane dehalogenase activity [GO:0018786]	haloalkane dehalogenase activity [GO:0018786]
d1iz7a__d2dsna___1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	response to toxic substance [GO:0009636]		periplasmic space [GO:0042597]		haloalkane dehalogenase activity [GO:0018786]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d1iz9a1_d2hk8g2__1			Deinococcus-Thermus	Aquificae	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	L-malate dehydrogenase activity [GO:0030060]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1iz9b1_d5uavb1__1		Metazoa	Deinococcus-Thermus	Chordata	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	L-malate dehydrogenase activity [GO:0030060]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1izca__d1u5va___1	Fungi		Ascomycota	Actinobacteria	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	lyase activity [GO:0016829]; magnesium ion binding [GO:0000287]; oxaloacetate metabolic process [GO:0006107]		oxaloacetate metabolic process [GO:0006107]			catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	lyase activity [GO:0016829]; magnesium ion binding [GO:0000287]
d1izda__d3sa3a___1	Fungi		Ascomycota		extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]			extracellular region [GO:0005576]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1izea__d3cyxb___1	Fungi		Ascomycota		extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1izhb__d1avf.2__1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]	extracellular space [GO:0005615]; aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; positive regulation of antibacterial peptide production [GO:0002803]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		digestion [GO:0007586]; positive regulation of antibacterial peptide production [GO:0002803]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		extracellular space [GO:0005615]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1izia__d1flha___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular exosome [GO:0070062]; multivesicular body lumen [GO:0097486]; aspartic-type endopeptidase activity [GO:0004190]; cellular protein metabolic process [GO:0044267]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cellular protein metabolic process [GO:0044267]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular exosome [GO:0070062]; multivesicular body lumen [GO:0097486]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1izja1_d1iknc___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	carbohydrate metabolic process [GO:0005975]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1izoa__d5cwea___1			Firmicutes	Actinobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1izob__d3tywb1__1			Firmicutes	Actinobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1izya__d1kxjb1__1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; glyoxalase III activity [GO:0019172]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; protein deglycase activity [GO:0036524]; thiolester hydrolase activity [GO:0016790]; zinc ion binding [GO:0008270]; DNA repair [GO:0006281]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to acidic pH [GO:0010447]; response to methylglyoxal [GO:0051595]; RNA repair [GO:0042245]	cytoplasm [GO:0005737]; glutaminase activity [GO:0004359]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; glutamine metabolic process [GO:0006541]; histidine biosynthetic process [GO:0000105]	DNA repair [GO:0006281]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to acidic pH [GO:0010447]; response to methylglyoxal [GO:0051595]; RNA repair [GO:0042245]	glutamine metabolic process [GO:0006541]; histidine biosynthetic process [GO:0000105]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	glyoxalase III activity [GO:0019172]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; protein deglycase activity [GO:0036524]; thiolester hydrolase activity [GO:0016790]; zinc ion binding [GO:0008270]	glutaminase activity [GO:0004359]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]
d1izyb__d3vu3a2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; glyoxalase III activity [GO:0019172]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; protein deglycase activity [GO:0036524]; thiolester hydrolase activity [GO:0016790]; zinc ion binding [GO:0008270]; DNA repair [GO:0006281]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to acidic pH [GO:0010447]; response to methylglyoxal [GO:0051595]; RNA repair [GO:0042245]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	DNA repair [GO:0006281]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to acidic pH [GO:0010447]; response to methylglyoxal [GO:0051595]; RNA repair [GO:0042245]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glyoxalase III activity [GO:0019172]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; protein deglycase activity [GO:0036524]; thiolester hydrolase activity [GO:0016790]; zinc ion binding [GO:0008270]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1izza__d1c3of2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; glyoxalase III activity [GO:0019172]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; protein deglycase activity [GO:0036524]; thiolester hydrolase activity [GO:0016790]; zinc ion binding [GO:0008270]; DNA repair [GO:0006281]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to acidic pH [GO:0010447]; response to methylglyoxal [GO:0051595]; RNA repair [GO:0042245]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	DNA repair [GO:0006281]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to acidic pH [GO:0010447]; response to methylglyoxal [GO:0051595]; RNA repair [GO:0042245]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	glyoxalase III activity [GO:0019172]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; protein deglycase activity [GO:0036524]; thiolester hydrolase activity [GO:0016790]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1j03a1_d1sv7a___1	Viridiplantae		Streptophyta		cytosol [GO:0005829]; nucleus [GO:0005634]; vacuole [GO:0005773]; steroid binding [GO:0005496]				cytosol [GO:0005829]; nucleus [GO:0005634]; vacuole [GO:0005773]		steroid binding [GO:0005496]	
d1j05a__d1jnhc1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	plasma membrane [GO:0005886]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	plasma membrane [GO:0005886]		
d1j05a__d1rzii2__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1j05b__d1bfob2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1j08a1_d1xtxa1__1			Euryarchaeota		cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]		electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	
d1j08a2_d2djka1__1		Fungi	Euryarchaeota	Ascomycota	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide isomerase activity [GO:0003756]
d1j08a2_d3o6td___1			Euryarchaeota	Actinobacteria	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; S-nitrosoglutathione reductase activity [GO:0080007]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; S-nitrosoglutathione reductase activity [GO:0080007]
d1j08c2_d2lkua___1		Viridiplantae	Euryarchaeota	Streptophyta	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d1j08d1_d2mzcb1__1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d1j08g1_d1j08h2__1			Euryarchaeota	Euryarchaeota	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d1j08g2_d4pngb1__1		Metazoa	Euryarchaeota	Arthropoda	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione transferase activity [GO:0004364]
d1j09a2_d3d6va1__1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	glutamyl-tRNA aminoacylation [GO:0006424]	tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]
d1j0bd__d2cleb1__1			Euryarchaeota	Proteobacteria	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]		tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]
d1j0bg__d1wdwf___1			Euryarchaeota	Euryarchaeota	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]	tryptophan synthase activity [GO:0004834]					1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]	tryptophan synthase activity [GO:0004834]
d1j0ca__d3x43c___1	Fungi		Ascomycota	Actinobacteria	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310]	cysteine synthase activity [GO:0004124]; antibiotic biosynthetic process [GO:0017000]; cysteine biosynthetic process from serine [GO:0006535]	amine catabolic process [GO:0009310]	antibiotic biosynthetic process [GO:0017000]; cysteine biosynthetic process from serine [GO:0006535]			1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]	cysteine synthase activity [GO:0004124]
d1j0cb__d1qoqb___1	Fungi		Ascomycota	Proteobacteria	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	amine catabolic process [GO:0009310]	tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]
d1j0cd__d1j0eb___1	Fungi	Fungi	Ascomycota	Ascomycota	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310]	amine catabolic process [GO:0009310]	amine catabolic process [GO:0009310]			1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]
d1j0da__d4aeca___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; cysteine synthase activity [GO:0004124]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]; double fertilization forming a zygote and endosperm [GO:0009567]; pollen tube growth [GO:0009860]	amine catabolic process [GO:0009310]	cysteine biosynthetic process from serine [GO:0006535]; double fertilization forming a zygote and endosperm [GO:0009567]; pollen tube growth [GO:0009860]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]	cysteine synthase activity [GO:0004124]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]
d1j0db__d1j0ba___1	Fungi		Ascomycota	Euryarchaeota	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]	amine catabolic process [GO:0009310]				1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]
d1j0dd__d2bhta1__1	Fungi		Ascomycota	Proteobacteria	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310]	cytoplasm [GO:0005737]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	amine catabolic process [GO:0009310]	cysteine biosynthetic process from serine [GO:0006535]		cytoplasm [GO:0005737]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]
d1j0ec__d5cvca1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310]	D-serine ammonia-lyase activity [GO:0008721]; L-serine ammonia-lyase activity [GO:0003941]; metal ion binding [GO:0046872]; protein self-association [GO:0043621]; serine racemase activity [GO:0030378]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]	amine catabolic process [GO:0009310]	D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]			1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]	D-serine ammonia-lyase activity [GO:0008721]; L-serine ammonia-lyase activity [GO:0003941]; metal ion binding [GO:0046872]; protein self-association [GO:0043621]; serine racemase activity [GO:0030378]
d1j0ha1_d2j3sb3__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	carbohydrate metabolic process [GO:0005975]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]		actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d1j0ha3_d2wb5b2__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d1j0ib1_d3o7yd1__1			Firmicutes		metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	
d1j0ja2_d1xsic3__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1j0ja3_d1ciua4__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1j0jb1_d5ijub___1			Firmicutes		metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	
d1j0jb3_d3vd3c3__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1j0ka1_d1eh9a1__1			Firmicutes	Crenarchaeota	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]
d1j0ka1_d3jv4b___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	carbohydrate metabolic process [GO:0005975]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]		centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d1j0kb3_d2x40a1__1			Firmicutes	Thermotogae	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1j0ma1_d1ojoa1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	polysaccharide metabolic process [GO:0005976]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d1j0ma3_d3t09b5__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide metabolic process [GO:0005976]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1j0na1_d2e24a1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	polysaccharide metabolic process [GO:0005976]	polysaccharide metabolic process [GO:0005976]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]
d1j0na3_d3t0ab5__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide metabolic process [GO:0005976]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1j0xo2_d1arzc2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; GAIT complex [GO:0097452]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; microtubule cytoskeleton organization [GO:0000226]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; protein stabilization [GO:0050821]; regulation of translation [GO:0006417]	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; cellular amino acid biosynthetic process [GO:0008652]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; microtubule cytoskeleton organization [GO:0000226]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; protein stabilization [GO:0050821]; regulation of translation [GO:0006417]	cellular amino acid biosynthetic process [GO:0008652]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; GAIT complex [GO:0097452]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634]	cytosol [GO:0005829]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]
d1j0ya2_d1wzlb3__1			Firmicutes	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1j0ya2_d3ndyd___1			Firmicutes	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]			amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]
d1j0yb2_d2nt1a2__1		Metazoa	Firmicutes	Chordata	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	polysaccharide catabolic process [GO:0000272]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1j0yc2_d1v3ma4__1			Firmicutes	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1j0yc2_d8a3ha___1			Firmicutes	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]
d1j0yd1_d1eo5a2__1			Firmicutes	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1j0za2_d3wloa1__1		Viridiplantae	Firmicutes	Streptophyta	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1j0zb1_d1a47a2__1			Firmicutes	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1j0zc2_d1kxqd2__1		Metazoa	Firmicutes	Chordata	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	polysaccharide catabolic process [GO:0000272]	carbohydrate catabolic process [GO:0016052]		extracellular space [GO:0005615]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1j0zd1_d2fhba3__1			Firmicutes	Proteobacteria	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		plasma membrane [GO:0005886]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]
d1j0zd2_d2zxbb1__1			Firmicutes	Thermotogae	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	polysaccharide catabolic process [GO:0000272]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]		lysosome [GO:0005764]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-L-fucosidase activity [GO:0004560]
d1j10c2_d3mmub___1			Firmicutes	Thermotogae	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	polysaccharide catabolic process [GO:0000272]	cellular glucan metabolic process [GO:0006073]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1j10d2_d1ta3a___1		Viridiplantae	Firmicutes	Streptophyta	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; enzyme inhibitor activity [GO:0004857]; carbohydrate metabolic process [GO:0005975]; defense response to fungus [GO:0050832]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; defense response to fungus [GO:0050832]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	enzyme inhibitor activity [GO:0004857]
d1j11a2_d3dyod3__1			Firmicutes	Proteobacteria	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1j11b2_d1ieva1__1		Viridiplantae	Firmicutes	Streptophyta	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1j11c1_d5ghld___1		Fungi	Firmicutes	Ascomycota	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	endoplasmic reticulum [GO:0005783]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]; polysaccharide metabolic process [GO:0005976]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]; polysaccharide metabolic process [GO:0005976]		endoplasmic reticulum [GO:0005783]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]
d1j11c2_d3gbda1__1			Firmicutes	Proteobacteria	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	isomaltulose synthase activity [GO:0050006]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	isomaltulose synthase activity [GO:0050006]
d1j12a2_d1jz1m5__1			Firmicutes		amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]				amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	
d1j12d2_d5d9pa___1			Firmicutes	Bacteroidetes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1j19a1_d1ni2a1__1	Metazoa	Metazoa	Chordata	Chordata	cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; uropod [GO:0001931]; integrin binding [GO:0005178]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]	actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; uropod [GO:0001931]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]	integrin binding [GO:0005178]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]
d1j19a1_d3qija2__1	Metazoa	Metazoa	Chordata	Chordata	cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; uropod [GO:0001931]; integrin binding [GO:0005178]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]	actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; uropod [GO:0001931]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	integrin binding [GO:0005178]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]
d1j19a3_d4nqlb___1	Metazoa	Metazoa	Chordata	Chordata	cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; uropod [GO:0001931]; integrin binding [GO:0005178]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; uropod [GO:0001931]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	integrin binding [GO:0005178]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1j1ba__d2hakf___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; beta-catenin destruction complex [GO:0030877]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Wnt signalosome [GO:1990909]; ATP binding [GO:0005524]; beta-catenin binding [GO:0008013]; dynactin binding [GO:0034452]; kinase activity [GO:0016301]; NF-kappaB binding [GO:0051059]; p53 binding [GO:0002039]; protease binding [GO:0002020]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II transcription factor binding [GO:0001085]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; ubiquitin protein ligase binding [GO:0031625]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular response to amyloid-beta [GO:1904646]; cellular response to interleukin-3 [GO:0036016]; circadian rhythm [GO:0007623]; dopamine receptor signaling pathway [GO:0007212]; epithelial to mesenchymal transition [GO:0001837]; ER overload response [GO:0006983]; establishment of cell polarity [GO:0030010]; excitatory postsynaptic potential [GO:0060079]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glycogen metabolic process [GO:0005977]; hippocampus development [GO:0021766]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of dendrite development [GO:2000171]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of neuron death [GO:1901215]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of type B pancreatic cell development [GO:2000077]; neuron projection development [GO:0031175]; neuron projection organization [GO:0106027]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of autophagy [GO:0010508]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of neuron death [GO:1901216]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein localization to centrosome [GO:1904781]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon extension [GO:0030516]; regulation of axonogenesis [GO:0050770]; regulation of cellular response to heat [GO:1900034]; regulation of circadian rhythm [GO:0042752]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of microtubule anchoring at centrosome [GO:0150101]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of microtubule-based process [GO:0032886]; regulation of synaptic vesicle exocytosis [GO:2000300]; signal transduction [GO:0007165]; superior temporal gyrus development [GO:0071109]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; microtubule cytoskeleton [GO:0015630]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; cytoskeleton organization [GO:0007010]; establishment of mitochondrion localization [GO:0051654]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; neuron migration [GO:0001764]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of dendrite development [GO:0050773]; regulation of neuron projection development [GO:0010975]; Wnt signaling pathway [GO:0016055]	beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular response to amyloid-beta [GO:1904646]; cellular response to interleukin-3 [GO:0036016]; circadian rhythm [GO:0007623]; dopamine receptor signaling pathway [GO:0007212]; epithelial to mesenchymal transition [GO:0001837]; ER overload response [GO:0006983]; establishment of cell polarity [GO:0030010]; excitatory postsynaptic potential [GO:0060079]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glycogen metabolic process [GO:0005977]; hippocampus development [GO:0021766]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of dendrite development [GO:2000171]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of neuron death [GO:1901215]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of type B pancreatic cell development [GO:2000077]; neuron projection development [GO:0031175]; neuron projection organization [GO:0106027]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of autophagy [GO:0010508]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of neuron death [GO:1901216]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein localization to centrosome [GO:1904781]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon extension [GO:0030516]; regulation of axonogenesis [GO:0050770]; regulation of cellular response to heat [GO:1900034]; regulation of circadian rhythm [GO:0042752]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of microtubule anchoring at centrosome [GO:0150101]; regulation of microtubule-based process [GO:0032886]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of synaptic vesicle exocytosis [GO:2000300]; signal transduction [GO:0007165]; superior temporal gyrus development [GO:0071109]; Wnt signaling pathway [GO:0016055]	cytoskeleton organization [GO:0007010]; establishment of mitochondrion localization [GO:0051654]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; neuron migration [GO:0001764]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of dendrite development [GO:0050773]; regulation of neuron projection development [GO:0010975]; Wnt signaling pathway [GO:0016055]	axon [GO:0030424]; beta-catenin destruction complex [GO:0030877]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Wnt signalosome [GO:1990909]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; microtubule cytoskeleton [GO:0015630]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; beta-catenin binding [GO:0008013]; dynactin binding [GO:0034452]; kinase activity [GO:0016301]; NF-kappaB binding [GO:0051059]; p53 binding [GO:0002039]; protease binding [GO:0002020]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II transcription factor binding [GO:0001085]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]
d1j1ma__d3hitb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1j1na__d4io6b1__1		Metazoa	Proteobacteria	Rotifera (rotifers)	metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; G protein-coupled receptor activity [GO:0004930]; ligand-gated ion channel activity [GO:0015276]				integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]	G protein-coupled receptor activity [GO:0004930]; ligand-gated ion channel activity [GO:0015276]
d1j1oy__d1lz2a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1j1py__d1kw7a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1j1wa__d1tyob___1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; tricarboxylic acid cycle [GO:0006099]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]		isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1j1wa__d2qfwe___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1j1wd__d4aj3a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1j1xh__d2jixh2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1j1xh__d5b8cf1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1j1zb1_d5us8b1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; arginine biosynthetic process [GO:0006526]	arginine biosynthetic process [GO:0006526]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]	argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]
d1j1zd1_d1mbza1__1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]	(carboxyethyl)arginine beta-lactam-synthase activity [GO:0034027]; asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; asparagine biosynthetic process [GO:0006529]; clavulanic acid biosynthetic process [GO:0033050]	arginine biosynthetic process [GO:0006526]	asparagine biosynthetic process [GO:0006529]; clavulanic acid biosynthetic process [GO:0033050]	cytoplasm [GO:0005737]		argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]	(carboxyethyl)arginine beta-lactam-synthase activity [GO:0034027]; asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d1j20b1_d4kpub___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	arginine biosynthetic process [GO:0006526]		cytoplasm [GO:0005737]		argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]
d1j22a__d1esga___1			Euryarchaeota	Firmicutes	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; DNA repair [GO:0006281]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA repair [GO:0006281]	DNA restriction-modification system [GO:0009307]			3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]
d1j23a__d2bhna2__1			Euryarchaeota	Crenarchaeota	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; DNA repair [GO:0006281]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	DNA repair [GO:0006281]	DNA repair [GO:0006281]			3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d1j24a__d2bgwb2__1			Euryarchaeota	Crenarchaeota	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; DNA repair [GO:0006281]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	DNA repair [GO:0006281]	DNA repair [GO:0006281]			3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d1j2ea2_d5egng___1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	methyl indole-3-acetate esterase activity [GO:0080030]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	methyl indole-3-acetate esterase activity [GO:0080030]
d1j2ga1_d1is7d___1		Metazoa	Firmicutes	Chordata	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]; allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]
d1j2gc2_d1gtpj___1			Firmicutes	Proteobacteria	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]; allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1j2gc2_d2yzbf1__1			Firmicutes	Actinobacteria	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]; allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]			carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1j2gd2_d2yzcd1__1			Firmicutes	Actinobacteria	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]; allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]			carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1j2ib1_d3eg5a___1		Metazoa		Chordata		brush border [GO:0005903]; cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; profilin binding [GO:0005522]; Rho GTPase binding [GO:0017048]; actin cytoskeleton organization [GO:0030036]; actin filament polymerization [GO:0030041]; brain development [GO:0007420]; cellular response to histamine [GO:0071420]; cytoskeleton organization [GO:0007010]; neuron projection development [GO:0031175]; positive regulation of cell migration [GO:0030335]; protein localization to microtubule [GO:0035372]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule-based process [GO:0032886]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; sensory perception of sound [GO:0007605]		actin cytoskeleton organization [GO:0030036]; actin filament polymerization [GO:0030041]; brain development [GO:0007420]; cellular response to histamine [GO:0071420]; cytoskeleton organization [GO:0007010]; neuron projection development [GO:0031175]; positive regulation of cell migration [GO:0030335]; protein localization to microtubule [GO:0035372]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule-based process [GO:0032886]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; sensory perception of sound [GO:0007605]		brush border [GO:0005903]; cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]		actin binding [GO:0003779]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; profilin binding [GO:0005522]; Rho GTPase binding [GO:0017048]
d1j2ja1_d4d6da1__1	Metazoa		Chordata		cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]		cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]		cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]		ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	
d1j2pb__d3c92c1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1j2pc__d5bxlq___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1j2qg__d5trgv___1			Euryarchaeota	Actinobacteria	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	threonine-type endopeptidase activity [GO:0004298]	threonine-type endopeptidase activity [GO:0004298]
d1j2qj__d5l5qq___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1j2wa__d3taka___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	deoxyribose-phosphate aldolase activity [GO:0004139]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1j2ya__d4rc9c___1			Proteobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1j34b__d4caja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; (1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]		detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	(1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]
d1j35b__d5b1wa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; CD8-positive, alpha-beta T cell activation [GO:0036037]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; negative regulation of tumor necrosis factor production [GO:0032720]; plasmacytoid dendritic cell antigen processing and presentation [GO:0002470]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; CD8-positive, alpha-beta T cell activation [GO:0036037]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; negative regulation of tumor necrosis factor production [GO:0032720]; plasmacytoid dendritic cell antigen processing and presentation [GO:0002470]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	extracellular region [GO:0005576]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]
d1j36a1_d3scia___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; sperm individualization [GO:0007291]; spermatid nucleus differentiation [GO:0007289]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; spermatid nucleus differentiation [GO:0007289]; sperm individualization [GO:0007291]	angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1j36b1_d1qf0a___1	Metazoa		Arthropoda	Firmicutes	extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; sperm individualization [GO:0007291]; spermatid nucleus differentiation [GO:0007289]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; spermatid nucleus differentiation [GO:0007289]; sperm individualization [GO:0007291]		extracellular space [GO:0005615]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1j36b1_d2x8ya___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; sperm individualization [GO:0007291]; spermatid nucleus differentiation [GO:0007289]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; sperm individualization [GO:0007291]; spermatid nucleus differentiation [GO:0007289]	metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; spermatid nucleus differentiation [GO:0007289]; sperm individualization [GO:0007291]	metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; spermatid nucleus differentiation [GO:0007289]; sperm individualization [GO:0007291]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]
d1j38a1_d1gxwa___1	Metazoa		Arthropoda	Firmicutes	extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; sperm individualization [GO:0007291]; spermatid nucleus differentiation [GO:0007289]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; spermatid nucleus differentiation [GO:0007289]; sperm individualization [GO:0007291]		extracellular space [GO:0005615]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1j3ca__d1i11a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; enhancer sequence-specific DNA binding [GO:0001158]; four-way junction DNA binding [GO:0000400]; non-sequence-specific DNA binding, bending [GO:0044378]; protein domain specific binding [GO:0019904]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription factor binding [GO:0008134]; chemotaxis [GO:0006935]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; DNA geometric change [GO:0032392]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA topological change [GO:0006265]; inflammatory response to antigenic stimulus [GO:0002437]; innate immune response [GO:0045087]; male gonad development [GO:0008584]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of gene expression [GO:0010629]; nucleosome assembly [GO:0006334]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]; response to steroid hormone [GO:0048545]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]	nuclear transcription factor complex [GO:0044798]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription regulatory region DNA binding [GO:0044212]; asymmetric neuroblast division [GO:0055059]; cartilage development [GO:0051216]; cell fate commitment [GO:0045165]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system neuron differentiation [GO:0021953]; in utero embryonic development [GO:0001701]; negative regulation of transcription, DNA-templated [GO:0045892]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cartilage development [GO:0061036]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of mesenchymal stem cell differentiation [GO:2000741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of timing of neuron differentiation [GO:0060164]	chemotaxis [GO:0006935]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; DNA geometric change [GO:0032392]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA topological change [GO:0006265]; inflammatory response to antigenic stimulus [GO:0002437]; innate immune response [GO:0045087]; male gonad development [GO:0008584]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of gene expression [GO:0010629]; nucleosome assembly [GO:0006334]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]; response to steroid hormone [GO:0048545]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]	asymmetric neuroblast division [GO:0055059]; cartilage development [GO:0051216]; cell fate commitment [GO:0045165]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system neuron differentiation [GO:0021953]; in utero embryonic development [GO:0001701]; negative regulation of transcription, DNA-templated [GO:0045892]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cartilage development [GO:0061036]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of mesenchymal stem cell differentiation [GO:2000741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of timing of neuron differentiation [GO:0060164]	cell [GO:0005623]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	nuclear transcription factor complex [GO:0044798]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; enhancer sequence-specific DNA binding [GO:0001158]; four-way junction DNA binding [GO:0000400]; non-sequence-specific DNA binding, bending [GO:0044378]; protein domain specific binding [GO:0019904]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription factor binding [GO:0008134]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription regulatory region DNA binding [GO:0044212]
d1j3jc__d1i00b___1		Metazoa	Apicomplexa	Chordata	dihydrofolate reductase activity [GO:0004146]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	dihydrofolate reductase activity [GO:0004146]; thymidylate synthase activity [GO:0004799]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1j3na1_d2vb9b2__1			Deinococcus-Thermus	Proteobacteria	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1j3na2_d2gfya2__1			Deinococcus-Thermus	Proteobacteria	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]		cytosol [GO:0005829]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1j3nb1_d4c6wa1__1			Deinococcus-Thermus		beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]				beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	
d1j3pa__d1ipja1__1		Viridiplantae	Euryarchaeota	Streptophyta	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]	nutrient reservoir activity [GO:0045735]
d1j3qa__d2gc0a2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]
d1j3rb__d3sxwa1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]
d1j3ua__d2e9fd___1			Firmicutes	Deinococcus-Thermus	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]; aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; argininosuccinate lyase activity [GO:0004056]; arginine biosynthetic process via ornithine [GO:0042450]	aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	arginine biosynthetic process via ornithine [GO:0042450]		cytoplasm [GO:0005737]	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]	argininosuccinate lyase activity [GO:0004056]
d1j3wd__d2e8jb___1		Metazoa	Deinococcus-Thermus	Chordata	guanyl-nucleotide exchange factor activity [GO:0005085]; molecular adaptor activity [GO:0060090]; positive regulation of TOR signaling [GO:0032008]	centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; membrane [GO:0016020]; microtubule [GO:0005874]; dynein intermediate chain binding [GO:0045505]; microtubule motor activity [GO:0003777]; intraciliary transport involved in cilium assembly [GO:0035735]; microtubule-based movement [GO:0007018]; visual behavior [GO:0007632]	positive regulation of TOR signaling [GO:0032008]	intraciliary transport involved in cilium assembly [GO:0035735]; microtubule-based movement [GO:0007018]; visual behavior [GO:0007632]		centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; membrane [GO:0016020]; microtubule [GO:0005874]	guanyl-nucleotide exchange factor activity [GO:0005085]; molecular adaptor activity [GO:0060090]	dynein intermediate chain binding [GO:0045505]; microtubule motor activity [GO:0003777]
d1j3ya__d1yhue___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1j3yg__d1fsxb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1j3zf__d1idra___1	Metazoa		Chordata	Actinobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1j40e__d3wcuh___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1j40g__d5nb4i___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1j41f__d1rteb___1	Metazoa		Chordata	Actinobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1j41g__d2uung___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1j42a__d3pq7b2__1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1j48a__d2cbta___1			Actinobacteria	Actinobacteria	DNA binding [GO:0003677]; defense response to bacterium [GO:0042742]	DNA binding [GO:0003677]; defense response to bacterium [GO:0042742]	defense response to bacterium [GO:0042742]	defense response to bacterium [GO:0042742]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1j49a1_d4fj2a___1		Fungi	Firmicutes	Ascomycota	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]					D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1j49b1_d4jcod1__1			Firmicutes	Euryarchaeota	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]	L-malate dehydrogenase activity [GO:0030060]
d1j4ac1_d2h5lf1__1		Metazoa	Firmicutes	Chordata	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]
d1j4ac1_d4pzec1__1			Firmicutes	Proteobacteria	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]		fatty acid metabolic process [GO:0006631]			D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d1j4ea__d3pg9a___1	Metazoa		Chordata	Thermotogae	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	I band [GO:0031674]; M band [GO:0031430]		fructose-bisphosphate aldolase activity [GO:0004332]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]
d1j4ec__d5dbug___1	Metazoa		Chordata	Firmicutes	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	I band [GO:0031674]; M band [GO:0031430]	cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	deoxyribose-phosphate aldolase activity [GO:0004139]
d1j4gb__d2zr1c___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process in other organism [GO:0044533]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]	defense response [GO:0006952]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process in other organism [GO:0044533]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1j4ia__d5owja2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; 'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]; response to heat [GO:0009408]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	cytosol [GO:0005829]; membrane [GO:0016020]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]
d1j4oa__d5jere___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]
d1j4ra__d1fkka___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018]; activin binding [GO:0048185]; calcium channel inhibitor activity [GO:0019855]; drug binding [GO:0008144]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein homodimerization activity [GO:0042803]; SMAD binding [GO:0046332]; amyloid fibril formation [GO:1990000]; chaperone-mediated protein folding [GO:0061077]; cytokine-mediated signaling pathway [GO:0019221]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; muscle contraction [GO:0006936]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of release of sequestered calcium ion into cytosol [GO:0051280]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; release of sequestered calcium ion into cytosol [GO:0051209]; response to caffeine [GO:0031000]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; T cell proliferation [GO:0042098]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	amyloid fibril formation [GO:1990000]; chaperone-mediated protein folding [GO:0061077]; cytokine-mediated signaling pathway [GO:0019221]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; muscle contraction [GO:0006936]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of release of sequestered calcium ion into cytosol [GO:0051280]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; release of sequestered calcium ion into cytosol [GO:0051209]; response to caffeine [GO:0031000]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; T cell proliferation [GO:0042098]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	activin binding [GO:0048185]; calcium channel inhibitor activity [GO:0019855]; drug binding [GO:0008144]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein homodimerization activity [GO:0042803]; SMAD binding [GO:0046332]
d1j4tb__d1kuj.1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]
d1j4tb__d4pita1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d1j4te__d4pitc1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d1j4ub__d4ddnc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d1j4wa1_d1ztgd1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; positive regulation of gene expression [GO:0010628]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; cadherin binding [GO:0045296]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; sequence-specific single stranded DNA binding [GO:0098847]; single-stranded DNA binding [GO:0003697]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA metabolic process [GO:0016070]; viral RNA genome replication [GO:0039694]	positive regulation of gene expression [GO:0010628]; transcription by RNA polymerase II [GO:0006366]	mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA metabolic process [GO:0016070]; viral RNA genome replication [GO:0039694]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]	cadherin binding [GO:0045296]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; sequence-specific single stranded DNA binding [GO:0098847]; single-stranded DNA binding [GO:0003697]
d1j4zc2_d1q3qb2__1				Euryarchaeota		ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]		protein folding [GO:0006457]				ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1j4zd2_d1q3se2__1				Euryarchaeota		ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]		protein folding [GO:0006457]				ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1j4zg2_d1q2vc2__1				Euryarchaeota		ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]		protein folding [GO:0006457]				ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1j4zg2_d1we3j2__1												
d1j4zh2_d1a6db2__1				Euryarchaeota		ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]		protein folding [GO:0006457]				ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1j4zi2_d1grla2__1				Proteobacteria		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]		'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]
d1j4zi2_d1q3rb2__1				Euryarchaeota		ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]		protein folding [GO:0006457]				ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1j4zj2_d1a6da2__1				Euryarchaeota		ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]		protein folding [GO:0006457]				ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1j4zm2_d1oelb2__1				Proteobacteria		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]		'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]
d1j51c__d2vrva___1			Proteobacteria		cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	
d1j56a__d1a2ob1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphorelay response regulator activity [GO:0000156]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; nitrogen fixation [GO:0009399]; regulation of nitrogen utilization [GO:0006808]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; phosphorelay response regulator activity [GO:0000156]; protein-glutamate methylesterase activity [GO:0008984]; protein-glutamine glutaminase activity [GO:0050568]; chemotaxis [GO:0006935]; protein deamination [GO:0018277]; protein demethylation [GO:0006482]	nitrogen fixation [GO:0009399]; regulation of nitrogen utilization [GO:0006808]; regulation of transcription, DNA-templated [GO:0006355]	chemotaxis [GO:0006935]; protein deamination [GO:0018277]; protein demethylation [GO:0006482]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; phosphorelay response regulator activity [GO:0000156]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	phosphorelay response regulator activity [GO:0000156]; protein-glutamate methylesterase activity [GO:0008984]; protein-glutamine glutaminase activity [GO:0050568]
d1j5da__d1l9sb1__1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1j5ee1_d3m85f1__1			Deinococcus-Thermus	Euryarchaeota	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	translation [GO:0006412]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	ribosome [GO:0005840]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1j5em__d2qbjm1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1j5ep__d2qanp1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1j5ha__d2cbma___1			Actinobacteria	Actinobacteria	DNA binding [GO:0003677]; defense response to bacterium [GO:0042742]	DNA binding [GO:0003677]; defense response to bacterium [GO:0042742]	defense response to bacterium [GO:0042742]	defense response to bacterium [GO:0042742]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1j5ka__d2ctka1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; podosome [GO:0002102]; cadherin binding [GO:0045296]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded DNA binding [GO:0003697]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045716]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902165]; regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter [GO:0072369]; regulation of low-density lipoprotein particle clearance [GO:0010988]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; signal transduction [GO:0007165]; viral process [GO:0016032]	cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]	mRNA splicing, via spliceosome [GO:0000398]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045716]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902165]; regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter [GO:0072369]; regulation of low-density lipoprotein particle clearance [GO:0010988]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; signal transduction [GO:0007165]; viral process [GO:0016032]	cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]	catalytic step 2 spliceosome [GO:0071013]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; podosome [GO:0002102]	cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded DNA binding [GO:0003697]	cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]
d1j5ol2_d4lssl2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	structural molecule activity [GO:0005198]
d1j5pa3_d3idsd2__1			Thermotogae		aspartate dehydrogenase activity [GO:0033735]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; NAD biosynthetic process [GO:0009435]	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	NAD biosynthetic process [GO:0009435]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		glycosome [GO:0020015]	aspartate dehydrogenase activity [GO:0033735]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1j5sa1_d1ndza___1		Metazoa	Thermotogae	Chordata	glucuronate isomerase activity [GO:0008880]; glucuronate catabolic process [GO:0006064]	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]; adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	glucuronate catabolic process [GO:0006064]	adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]		cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]	glucuronate isomerase activity [GO:0008880]	adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]
d1j6ra1_d1k7ya3__1			Thermotogae	Proteobacteria	methionine synthase activity [GO:0008705]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cobalamin binding [GO:0031419]; methionine synthase activity [GO:0008705]; protein methyltransferase activity [GO:0008276]; zinc ion binding [GO:0008270]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]		homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	methionine synthase activity [GO:0008705]	cobalamin binding [GO:0031419]; methionine synthase activity [GO:0008705]; protein methyltransferase activity [GO:0008276]; zinc ion binding [GO:0008270]
d1j70a1_d1xnja1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1j70b1_d1m8pc1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1j70b3_d4rkea1__1	Fungi	Metazoa	Ascomycota	Arthropoda	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	Golgi apparatus [GO:0005794]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynapse of neuromuscular junction [GO:0098975]; type II terminal bouton [GO:0061175]; vesicle [GO:0031982]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; intracellular protein transport [GO:0006886]; Rab protein signal transduction [GO:0032482]; regulation of glutamate receptor clustering [GO:0106104]; regulation of postsynapse organization [GO:0099175]; vesicle-mediated transport [GO:0016192]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	intracellular protein transport [GO:0006886]; Rab protein signal transduction [GO:0032482]; regulation of glutamate receptor clustering [GO:0106104]; regulation of postsynapse organization [GO:0099175]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	Golgi apparatus [GO:0005794]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynapse of neuromuscular junction [GO:0098975]; type II terminal bouton [GO:0061175]; vesicle [GO:0031982]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]
d1j70c2_d2b7lb___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]; glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]
d1j70c3_d2a5yc1__1	Fungi	Metazoa	Ascomycota	Nematoda (roundworms)	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cell junction [GO:0030054]; endomembrane system [GO:0012505]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; organelle membrane [GO:0031090]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; presynapse [GO:0098793]; GTPase activator activity [GO:0005096]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; actin filament depolymerization [GO:0030042]; apoptotic process [GO:0006915]; apoptotic process involved in development [GO:1902742]; autophagy of mitochondrion [GO:0000422]; defense response to Gram-negative bacterium [GO:0050829]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of programmed cell death [GO:0043069]; positive regulation of brood size [GO:0090727]; positive regulation of embryonic development [GO:0040019]; positive regulation of fertilization [GO:1905516]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of oviposition [GO:1901046]; positive regulation of synapse pruning [GO:1905808]; protein processing [GO:0016485]; regulation of synapse organization [GO:0050807]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	actin filament depolymerization [GO:0030042]; apoptotic process [GO:0006915]; apoptotic process involved in development [GO:1902742]; autophagy of mitochondrion [GO:0000422]; defense response to Gram-negative bacterium [GO:0050829]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of programmed cell death [GO:0043069]; positive regulation of brood size [GO:0090727]; positive regulation of embryonic development [GO:0040019]; positive regulation of fertilization [GO:1905516]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of oviposition [GO:1901046]; positive regulation of synapse pruning [GO:1905808]; protein processing [GO:0016485]; regulation of synapse organization [GO:0050807]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cell junction [GO:0030054]; endomembrane system [GO:0012505]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; organelle membrane [GO:0031090]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; presynapse [GO:0098793]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	GTPase activator activity [GO:0005096]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d1j72a2_d1f7sa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]	barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	actin filament depolymerization [GO:0030042]	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]	actin binding [GO:0003779]
d1j72a3_d1t3xa___1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; site of polarized growth [GO:0030427]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]; defense response to fungus [GO:0050832]; neutrophil degranulation [GO:0043312]; regulation of actin filament polymerization [GO:0030833]	barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	defense response to fungus [GO:0050832]; neutrophil degranulation [GO:0043312]; regulation of actin filament polymerization [GO:0030833]	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; site of polarized growth [GO:0030427]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]
d1j72a3_d3ffnb5__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1j78a3_d3cx9a3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]; vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1j7ba__d4c80a1__1			Cyanobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1j7ca__d5byra1__1			Cyanobacteria	Firmicutes	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]
d1j7ga__d1tc5d1__1			Proteobacteria		cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; D-tyrosyl-tRNA(Tyr) deacylase activity [GO:0051500]; Gly-tRNA(Ala) hydrolase activity [GO:0106026]; Ser(Gly)-tRNA(Ala) hydrolase activity [GO:0043908]; tRNA binding [GO:0000049]; D-amino acid catabolic process [GO:0019478]; tRNA metabolic process [GO:0006399]	cytoplasm [GO:0005737]; D-aminoacyl-tRNA deacylase activity [GO:0051499]	D-amino acid catabolic process [GO:0019478]; tRNA metabolic process [GO:0006399]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; D-tyrosyl-tRNA(Tyr) deacylase activity [GO:0051500]; Gly-tRNA(Ala) hydrolase activity [GO:0106026]; Ser(Gly)-tRNA(Ala) hydrolase activity [GO:0043908]; tRNA binding [GO:0000049]	D-aminoacyl-tRNA deacylase activity [GO:0051499]
d1j7sd__d1qxdd___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1j7vr1_d1n26a2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]; aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; ciliary neurotrophic factor receptor complex [GO:0070110]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor binding [GO:0070119]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; enzyme binding [GO:0019899]; interleukin-6 binding [GO:0019981]; interleukin-6 receptor activity [GO:0004915]; protein homodimerization activity [GO:0042803]; acute-phase response [GO:0006953]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; endocrine pancreas development [GO:0031018]; extrinsic apoptotic signaling pathway [GO:0097191]; hepatic immune response [GO:0002384]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of interleukin-8 production [GO:0032717]; neutrophil mediated immunity [GO:0002446]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of glomerular mesangial cell proliferation [GO:0072126]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to cytokine [GO:0034097]	aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	acute-phase response [GO:0006953]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; endocrine pancreas development [GO:0031018]; extrinsic apoptotic signaling pathway [GO:0097191]; hepatic immune response [GO:0002384]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of interleukin-8 production [GO:0032717]; neutrophil mediated immunity [GO:0002446]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of glomerular mesangial cell proliferation [GO:0072126]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to cytokine [GO:0034097]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; ciliary neurotrophic factor receptor complex [GO:0070110]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]	ciliary neurotrophic factor binding [GO:0070119]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; enzyme binding [GO:0019899]; interleukin-6 binding [GO:0019981]; interleukin-6 receptor activity [GO:0004915]; protein homodimerization activity [GO:0042803]
d1j7wd__d5nb4j___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1j7ya__d3goud___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1j84a__d3heie___1		Metazoa	Firmicutes	Chordata	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	cellulose catabolic process [GO:0030245]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]		cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]
d1j86a2_d4jfhd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	Fc-epsilon receptor signaling pathway [GO:0038095]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	IgE binding [GO:0019863]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1j86b1_d1t89c1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	Fc-epsilon receptor signaling pathway [GO:0038095]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	IgE binding [GO:0019863]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1j86b1_d3esuf2__1	Metazoa		Chordata		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]		Fc-epsilon receptor signaling pathway [GO:0038095]		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		IgE binding [GO:0019863]	
d1j88a1_d1efxd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	Fc-epsilon receptor signaling pathway [GO:0038095]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	IgE binding [GO:0019863]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1j88a2_d2cikb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	Fc-epsilon receptor signaling pathway [GO:0038095]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	IgE binding [GO:0019863]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1j88d1_d1ow0c1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]	Fc-epsilon receptor signaling pathway [GO:0038095]	cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	IgE binding [GO:0019863]	IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]
d1j88e1_d1ypze1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	Fc-epsilon receptor signaling pathway [GO:0038095]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	IgE binding [GO:0019863]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1j89a1_d1bqhi1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	Fc-epsilon receptor signaling pathway [GO:0038095]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	IgE binding [GO:0019863]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1j89a2_d1iilg2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	Fc-epsilon receptor signaling pathway [GO:0038095]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	IgE binding [GO:0019863]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1j89a2_d4xphl2__1	Metazoa	Metazoa	Chordata	Arthropoda	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]; adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	Fc-epsilon receptor signaling pathway [GO:0038095]	adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; neuronal cell body membrane [GO:0032809]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	IgE binding [GO:0019863]	cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]
d1j89d2_d4wi5b2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	Fc-epsilon receptor signaling pathway [GO:0038095]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	IgE binding [GO:0019863]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1j89e1_d5n2dd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	Fc-epsilon receptor signaling pathway [GO:0038095]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	IgE binding [GO:0019863]	
d1j8ca__d3a9jb___1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; polyubiquitin modification-dependent protein binding [GO:0031593]; autophagosome assembly [GO:0000045]; negative regulation of clathrin-dependent endocytosis [GO:1900186]; negative regulation of G protein-coupled receptor internalization [GO:1904021]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; regulation of autophagosome assembly [GO:2000785]; regulation of macroautophagy [GO:0016241]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome assembly [GO:0000045]; negative regulation of clathrin-dependent endocytosis [GO:1900186]; negative regulation of G protein-coupled receptor internalization [GO:1904021]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; regulation of autophagosome assembly [GO:2000785]; regulation of macroautophagy [GO:0016241]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	polyubiquitin modification-dependent protein binding [GO:0031593]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1j8fc__d3fznb2__1	Metazoa		Chordata	Proteobacteria	centriole [GO:0005814]; centrosome [GO:0005813]; chromatin silencing complex [GO:0005677]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glial cell projection [GO:0097386]; growth cone [GO:0030426]; juxtaparanode region of axon [GO:0044224]; lateral loop [GO:0043219]; meiotic spindle [GO:0072687]; microtubule [GO:0005874]; midbody [GO:0030496]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; myelin sheath [GO:0043209]; nuclear heterochromatin [GO:0005720]; nucleolus [GO:0005730]; nucleus [GO:0005634]; paranodal junction [GO:0033010]; paranode region of axon [GO:0033270]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; Schmidt-Lanterman incisure [GO:0043220]; spindle [GO:0005819]; chromatin binding [GO:0003682]; histone acetyltransferase binding [GO:0035035]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone deacetylase activity (H4-K16 specific) [GO:0046970]; NAD-dependent protein deacetylase activity [GO:0034979]; protein deacetylase activity [GO:0033558]; transcription factor binding [GO:0008134]; tubulin deacetylase activity [GO:0042903]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; cell division [GO:0051301]; cellular lipid catabolic process [GO:0044242]; cellular response to caloric restriction [GO:0061433]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to oxidative stress [GO:0034599]; chromatin silencing [GO:0006342]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at telomere [GO:0006348]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; innate immune response [GO:0045087]; meiotic cell cycle [GO:0051321]; myelination in peripheral nervous system [GO:0022011]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine deacetylation [GO:0034983]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of cell division [GO:0051781]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]; protein kinase B signaling [GO:0043491]; regulation of cell cycle [GO:0051726]; regulation of exit from mitosis [GO:0007096]; regulation of myelination [GO:0031641]; regulation of phosphorylation [GO:0042325]; response to redox state [GO:0051775]; substantia nigra development [GO:0021762]; tubulin deacetylation [GO:0090042]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	autophagy [GO:0006914]; cell division [GO:0051301]; cellular lipid catabolic process [GO:0044242]; cellular response to caloric restriction [GO:0061433]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to oxidative stress [GO:0034599]; chromatin silencing [GO:0006342]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at telomere [GO:0006348]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; innate immune response [GO:0045087]; meiotic cell cycle [GO:0051321]; myelination in peripheral nervous system [GO:0022011]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; peptidyl-lysine deacetylation [GO:0034983]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of cell division [GO:0051781]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]; protein kinase B signaling [GO:0043491]; regulation of cell cycle [GO:0051726]; regulation of exit from mitosis [GO:0007096]; regulation of myelination [GO:0031641]; regulation of phosphorylation [GO:0042325]; response to redox state [GO:0051775]; substantia nigra development [GO:0021762]; tubulin deacetylation [GO:0090042]	mandelate catabolic process [GO:0019596]	centriole [GO:0005814]; centrosome [GO:0005813]; chromatin silencing complex [GO:0005677]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glial cell projection [GO:0097386]; growth cone [GO:0030426]; juxtaparanode region of axon [GO:0044224]; lateral loop [GO:0043219]; meiotic spindle [GO:0072687]; microtubule [GO:0005874]; midbody [GO:0030496]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; myelin sheath [GO:0043209]; nuclear heterochromatin [GO:0005720]; nucleolus [GO:0005730]; nucleus [GO:0005634]; paranodal junction [GO:0033010]; paranode region of axon [GO:0033270]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; Schmidt-Lanterman incisure [GO:0043220]; spindle [GO:0005819]		chromatin binding [GO:0003682]; histone acetyltransferase binding [GO:0035035]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone deacetylase activity (H4-K16 specific) [GO:0046970]; NAD-dependent protein deacetylase activity [GO:0034979]; protein deacetylase activity [GO:0033558]; transcription factor binding [GO:0008134]; tubulin deacetylase activity [GO:0042903]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1j8ha1_d1yntc1__1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell wall [GO:0005618]; extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]
d1j8ha2_d3lkqa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1j8he1_d1yc7a1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1j8he1_d3bxnb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1j8va1_d5i78a1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulase activity [GO:0008810]
d1j90a__d2hldu2__1	Metazoa	Fungi	Arthropoda	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	ATP synthesis coupled proton transport [GO:0015986]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1j92b1_d1h4ca___1				Proteobacteria		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]; bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]		bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]		cytoplasm [GO:0005737]		GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]
d1j93a__d3ppha1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast [GO:0009507]; uroporphyrinogen decarboxylase activity [GO:0004853]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cell surface [GO:0009986]; fungal biofilm matrix [GO:0062040]; fungal-type cell wall [GO:0009277]; hyphal cell wall [GO:0030446]; nucleus [GO:0005634]; 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity [GO:0003871]; zinc ion binding [GO:0008270]; cellular response to heat [GO:0034605]; induction by symbiont of host defense response [GO:0044416]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]	chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cellular response to heat [GO:0034605]; induction by symbiont of host defense response [GO:0044416]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]	chloroplast [GO:0009507]	cell surface [GO:0009986]; fungal biofilm matrix [GO:0062040]; fungal-type cell wall [GO:0009277]; hyphal cell wall [GO:0030446]; nucleus [GO:0005634]	uroporphyrinogen decarboxylase activity [GO:0004853]	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity [GO:0003871]; zinc ion binding [GO:0008270]
d1j96a1_d3h7ra___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; steroid dehydrogenase activity [GO:0016229]; oxidation-reduction process [GO:0055114]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to salt stress [GO:0009651]; response to toxic substance [GO:0009636]; response to water deprivation [GO:0009414]	cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	oxidation-reduction process [GO:0055114]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to salt stress [GO:0009651]; response to toxic substance [GO:0009636]; response to water deprivation [GO:0009414]	cytosol [GO:0005829]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; steroid dehydrogenase activity [GO:0016229]
d1j9ch__d3su2a1__1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1j9ct2_d3k2md___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]
d1j9qb2_d2jfcd1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1j9qb2_d2ov0a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1j9qc1_d2gc7o___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1j9qc2_d1kbwf1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]	cell outer membrane [GO:0009279]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1j9ra1_d1e67c___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1j9sa1_d1ndrc1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1j9sa1_d1rkra___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1j9sb2_d3fpxa2__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1j9ta1_d4e9ta1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d1j9tb2_d4dp9x___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1j9tc2_d1ezlb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1j9tc2_d1kcwa2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	periplasmic space [GO:0042597]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d1j9za2_d5ljpa___1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cell [GO:0005623]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1j9za3_d2vnkd2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1ja0a2_d1ykga1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]
d1ja0b2_d1e63a2__1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	phycobilisome [GO:0030089]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d1ja1b3_d4dqkb2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d1ja8a1_d3esfc1__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ja9a__d4aj1c1__1	Fungi	Metazoa	Ascomycota	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		cytoplasm [GO:0005737]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1jac.5_d4pifd1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1jac.7_d1vbog___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1jafb__d1e83a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1jafb__d3iq6d___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1jaka1_d1blia2__1			Actinobacteria	Firmicutes	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	beta-N-acetylhexosaminidase activity [GO:0004563]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1jalb2_d2dwqa2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]	ATP binding [GO:0005524]; ATPase activity [GO:0016887]; GTP binding [GO:0005525]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]			cytoplasm [GO:0005737]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]
d1japa__d3o2xc1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1jaqa__d1zn3a___1	Metazoa		Chordata	Firmicutes	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	negative regulation of neurotransmitter secretion [GO:0046929]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1jasa__d2groa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; replication fork [GO:0005657]; XY body [GO:0001741]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular response to DNA damage stimulus [GO:0006974]; chiasma assembly [GO:0051026]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; histone H2A ubiquitination [GO:0033522]; histone lysine demethylation [GO:0070076]; in utero embryonic development [GO:0001701]; maintenance of chromatin silencing [GO:0006344]; meiotic telomere clustering [GO:0045141]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of histone phosphorylation [GO:0033128]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of reciprocal meiotic recombination [GO:0010845]; postreplication repair [GO:0006301]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; response to drug [GO:0042493]; response to UV [GO:0009411]; sperm axoneme assembly [GO:0007288]; spermatogenesis [GO:0007283]; synaptonemal complex organization [GO:0070193]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]; ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; chiasma assembly [GO:0051026]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; histone H2A ubiquitination [GO:0033522]; histone lysine demethylation [GO:0070076]; in utero embryonic development [GO:0001701]; maintenance of chromatin silencing [GO:0006344]; meiotic telomere clustering [GO:0045141]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of histone phosphorylation [GO:0033128]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of reciprocal meiotic recombination [GO:0010845]; postreplication repair [GO:0006301]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; response to drug [GO:0042493]; response to UV [GO:0009411]; spermatogenesis [GO:0007283]; sperm axoneme assembly [GO:0007288]; synaptonemal complex organization [GO:0070193]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cell [GO:0005623]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; replication fork [GO:0005657]; XY body [GO:0001741]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]
d1jata1_d3obqa___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin conjugating enzyme complex [GO:0031371]; ligase activity [GO:0016874]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]; cellular response to DNA damage stimulus [GO:0006974]; free ubiquitin chain polymerization [GO:0010994]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]; autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	cellular response to DNA damage stimulus [GO:0006974]; free ubiquitin chain polymerization [GO:0010994]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]	autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin conjugating enzyme complex [GO:0031371]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	ligase activity [GO:0016874]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]	calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]
d1jaya__d4jjga1__1			Euryarchaeota	Euryarchaeota	8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity [GO:0102261]; coenzyme F420 binding [GO:0070967]; NADP binding [GO:0050661]; reduced coenzyme F420:NADP+ oxidoreductase activity [GO:0052808]; NADPH regeneration [GO:0006740]	N5,N10-methenyltetrahydromethanopterin hydrogenase activity [GO:0047068]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	NADPH regeneration [GO:0006740]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]			8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity [GO:0102261]; coenzyme F420 binding [GO:0070967]; NADP binding [GO:0050661]; reduced coenzyme F420:NADP+ oxidoreductase activity [GO:0052808]	N5,N10-methenyltetrahydromethanopterin hydrogenase activity [GO:0047068]
d1jb2b__d1gy5b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]
d1jb2b__d5aewh___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]		identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1jb3a__d3ckib___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; basal part of cell [GO:0045178]; basement membrane [GO:0005604]; cell junction [GO:0030054]; extracellular matrix [GO:0031012]; extracellular matrix of synaptic cleft [GO:0098965]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; synapse [GO:0045202]; acetylcholine receptor regulator activity [GO:0030548]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; extracellular matrix binding [GO:0050840]; glycosaminoglycan binding [GO:0005539]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; laminin binding [GO:0043236]; laminin-1 binding [GO:0043237]; serine-type endopeptidase inhibitor activity [GO:0004867]; sialic acid binding [GO:0033691]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; negative regulation of neuron projection development [GO:0010977]; negative regulation of serine-type peptidase activity [GO:1902572]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; negative regulation of neuron projection development [GO:0010977]; negative regulation of serine-type peptidase activity [GO:1902572]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	axon [GO:0030424]; basal part of cell [GO:0045178]; basement membrane [GO:0005604]; cell junction [GO:0030054]; extracellular matrix [GO:0031012]; extracellular matrix of synaptic cleft [GO:0098965]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; synapse [GO:0045202]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	acetylcholine receptor regulator activity [GO:0030548]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; extracellular matrix binding [GO:0050840]; glycosaminoglycan binding [GO:0005539]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; laminin-1 binding [GO:0043237]; laminin binding [GO:0043236]; serine-type endopeptidase inhibitor activity [GO:0004867]; sialic acid binding [GO:0033691]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d1jb5a__d1jn5a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1jb7a3_d1j5el___1			Ciliophora	Deinococcus-Thermus	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	telomere capping [GO:0016233]	translation [GO:0006412]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	ribosome [GO:0005840]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1jb9a1_d5ue9d1__1	Viridiplantae		Streptophyta	Firmicutes	electron transfer activity [GO:0009055]; NADPH binding [GO:0070402]; NADPH dehydrogenase activity [GO:0003959]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; NADPH binding [GO:0070402]; NADPH dehydrogenase activity [GO:0003959]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]
d1jbaa__d1xfwq1__1	Metazoa	Metazoa	Chordata	Chordata	photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	response to stimulus [GO:0050896]; visual perception [GO:0007601]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1jbaa__d5w1fa___1	Metazoa	Metazoa	Chordata	Chordata	photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	response to stimulus [GO:0050896]; visual perception [GO:0007601]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium ion binding [GO:0005509]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1jbbb__d4yiiu___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin conjugating enzyme complex [GO:0031371]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; free ubiquitin chain polymerization [GO:0010994]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]	anaphase-promoting complex [GO:0005680]; cell [GO:0005623]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-protein transferase activity [GO:0004842]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; exit from mitosis [GO:0010458]; free ubiquitin chain polymerization [GO:0010994]; positive regulation of exit from mitosis [GO:0031536]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; ubiquitin-dependent protein catabolic process [GO:0006511]	free ubiquitin chain polymerization [GO:0010994]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; exit from mitosis [GO:0010458]; free ubiquitin chain polymerization [GO:0010994]; positive regulation of exit from mitosis [GO:0031536]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin conjugating enzyme complex [GO:0031371]	anaphase-promoting complex [GO:0005680]; cell [GO:0005623]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-protein transferase activity [GO:0004842]
d1jbha__d4i3be___1	Metazoa	Metazoa	Chordata	Chordata	cell body [GO:0044297]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; lipid homeostasis [GO:0055088]; regulation of granulocyte differentiation [GO:0030852]; response to vitamin A [GO:0033189]; retinoic acid biosynthetic process [GO:0002138]; retinol metabolic process [GO:0042572]; vitamin A metabolic process [GO:0006776]	cytoplasm [GO:0005737]; lipid binding [GO:0008289]; bioluminescence [GO:0008218]	lipid homeostasis [GO:0055088]; regulation of granulocyte differentiation [GO:0030852]; response to vitamin A [GO:0033189]; retinoic acid biosynthetic process [GO:0002138]; retinol metabolic process [GO:0042572]; vitamin A metabolic process [GO:0006776]	bioluminescence [GO:0008218]	cell body [GO:0044297]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinol binding [GO:0019841]	lipid binding [GO:0008289]
d1jbmb1_d1vu2d___1			Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]			
d1jbmd__d5mkne___1			Euryarchaeota	Euryarchaeota	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]			
d1jbme1_d1n9sa___1		Fungi	Euryarchaeota	Ascomycota	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	mRNA splicing, via spliceosome [GO:0000398]	mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	small nucleolar ribonucleoprotein complex [GO:0005732]	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]
d1jbmf1_d1h64m___1			Euryarchaeota	Euryarchaeota	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]			
d1jboa__d3d4xa___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	phycobilisome [GO:0030089]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1jbra__d1aqzb___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]; negative regulation of translation [GO:0017148]	negative regulation of translation [GO:0017148]	negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1jbrb__d1bsbb___1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	negative regulation of translation [GO:0017148]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1jc2a__d4n1gb___1	Metazoa	Metazoa	Chordata	Cnidaria	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	bioluminescence [GO:0008218]	troponin complex [GO:0005861]		actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]
d1jc7a__d1gxdd___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; basal part of cell [GO:0045178]; basement membrane [GO:0005604]; cell junction [GO:0030054]; extracellular matrix [GO:0031012]; extracellular matrix of synaptic cleft [GO:0098965]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; synapse [GO:0045202]; acetylcholine receptor regulator activity [GO:0030548]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; extracellular matrix binding [GO:0050840]; glycosaminoglycan binding [GO:0005539]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; laminin binding [GO:0043236]; laminin-1 binding [GO:0043237]; serine-type endopeptidase inhibitor activity [GO:0004867]; sialic acid binding [GO:0033691]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; negative regulation of neuron projection development [GO:0010977]; negative regulation of serine-type peptidase activity [GO:1902572]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; negative regulation of neuron projection development [GO:0010977]; negative regulation of serine-type peptidase activity [GO:1902572]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]	angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	axon [GO:0030424]; basal part of cell [GO:0045178]; basement membrane [GO:0005604]; cell junction [GO:0030054]; extracellular matrix [GO:0031012]; extracellular matrix of synaptic cleft [GO:0098965]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; synapse [GO:0045202]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]	acetylcholine receptor regulator activity [GO:0030548]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; extracellular matrix binding [GO:0050840]; glycosaminoglycan binding [GO:0005539]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; laminin-1 binding [GO:0043237]; laminin binding [GO:0043236]; serine-type endopeptidase inhibitor activity [GO:0004867]; sialic acid binding [GO:0033691]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]	metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1jc9a__d2j3fd___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cell-cell adhesion [GO:0098609]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	cell-cell adhesion [GO:0098609]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	extracellular region [GO:0005576]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1jcfa2_d1nlva2__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cytoplasm [GO:0005737]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1jcga2_d2i7nb2__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	cell periphery [GO:0071944]; clathrin coat [GO:0030118]; cytosol [GO:0005829]; nucleus [GO:0005634]; recycling endosome [GO:0055037]; acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; coenzyme A biosynthetic process [GO:0015937]; coenzyme biosynthetic process [GO:0009108]	cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	coenzyme A biosynthetic process [GO:0015937]; coenzyme biosynthetic process [GO:0009108]	cytoplasm [GO:0005737]	cell periphery [GO:0071944]; clathrin coat [GO:0030118]; cytosol [GO:0005829]; nucleus [GO:0005634]; recycling endosome [GO:0055037]	ATP binding [GO:0005524]	acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]
d1jcga2_d5aqsa2__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d1jcka1_d5lmjb1__1			Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d1jcka2_d4qrre2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1jckc1_d1aqkh1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1jckc1_d3ra7m1__1			Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d1jckc2_d5mwnf1__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d1jckd2_d3owen2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d1jclb1_d4r53a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; deoxyribose-phosphate aldolase activity [GO:0004139]; lyase activity [GO:0016829]; carbohydrate catabolic process [GO:0016052]; cellular response to DNA damage stimulus [GO:0006974]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]; nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate catabolic process [GO:0016052]; cellular response to DNA damage stimulus [GO:0006974]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]; nucleobase-containing small molecule interconversion [GO:0015949]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	deoxyribose-phosphate aldolase activity [GO:0004139]; lyase activity [GO:0016829]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1jcqa__d1tnuc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]; protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]; protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1jcrb__d1o79a2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1jcrb__d1tnbh___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1jcsa__d4ydoa___1	Metazoa	Fungi	Chordata	Ascomycota	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1jcta1_d1ec9d1__1			Proteobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	D-glucarate catabolic process [GO:0042838]	D-glucarate catabolic process [GO:0042838]			glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d1jczb__d2hfxa___1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; chloride ion homeostasis [GO:0055064]		bicarbonate transport [GO:0015701]; chloride ion homeostasis [GO:0055064]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	
d1jd1b__d3lmeg1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]		organonitrogen compound catabolic process [GO:1901565]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		deaminase activity [GO:0019239]	
d1jd1c__d1qaha___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]; deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ion binding [GO:0043167]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; transition metal ion binding [GO:0046914]; brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	organonitrogen compound catabolic process [GO:1901565]	brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]	deaminase activity [GO:0019239]	deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ion binding [GO:0043167]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; transition metal ion binding [GO:0046914]
d1jd1c__d3l7qd___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]		organonitrogen compound catabolic process [GO:1901565]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		deaminase activity [GO:0019239]	
d1jd1e__d2chth___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	organonitrogen compound catabolic process [GO:1901565]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	deaminase activity [GO:0019239]	chorismate mutase activity [GO:0004106]
d1jd1f__d2chsh___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	organonitrogen compound catabolic process [GO:1901565]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	deaminase activity [GO:0019239]	chorismate mutase activity [GO:0004106]
d1jd22__d5l5ys___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1jd2d__d4qzzk___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1jd2f__d5l6co___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1jd2g__d4ya1m___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1jd2q__d5l5zo___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1jd2s__d5lajq___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1jd7a1_d2qv4a1__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular region [GO:0005576]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1jd9a1_d5u3aa2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular region [GO:0005576]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1jdbb3_d5c1pb1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1jdbb4_d2hgsa1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; glutathione binding [GO:0043295]; glutathione synthase activity [GO:0004363]; glycine binding [GO:0016594]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; cellular amino acid metabolic process [GO:0006520]; glutathione biosynthetic process [GO:0006750]; nervous system development [GO:0007399]; response to amino acid [GO:0043200]; response to cadmium ion [GO:0046686]; response to nutrient levels [GO:0031667]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to xenobiotic stimulus [GO:0009410]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	aging [GO:0007568]; cellular amino acid metabolic process [GO:0006520]; glutathione biosynthetic process [GO:0006750]; nervous system development [GO:0007399]; response to amino acid [GO:0043200]; response to cadmium ion [GO:0046686]; response to nutrient levels [GO:0031667]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to xenobiotic stimulus [GO:0009410]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; glutathione binding [GO:0043295]; glutathione synthase activity [GO:0004363]; glycine binding [GO:0016594]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]
d1jdbe4_d1b6ra2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]
d1jdbh2_d1ik4f___1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	methylglyoxal synthase activity [GO:0008929]
d1jdbh4_d2yrxa1__1			Proteobacteria	Firmicutes	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d1jdca2_d1dhka2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; starch catabolic process [GO:0005983]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	starch catabolic process [GO:0005983]	carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1jdea2_d5lu4b2__1		Viridiplantae	Firmicutes	Streptophyta	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]	chloroplast [GO:0009507]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; photosynthesis [GO:0015979]; pyruvate metabolic process [GO:0006090]	pyruvate metabolic process [GO:0006090]	photosynthesis [GO:0015979]; pyruvate metabolic process [GO:0006090]		chloroplast [GO:0009507]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]
d1jdea3_d1kc7a3__1			Firmicutes	Firmicutes	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]	pyruvate metabolic process [GO:0006090]	pyruvate metabolic process [GO:0006090]			ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]
d1jdfa1_d1xs2d1__1			Proteobacteria	Deinococcus-Thermus	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	D-glucarate catabolic process [GO:0042838]	menaquinone biosynthetic process [GO:0009234]			glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d1jdfb1_d1onea1__1		Fungi	Proteobacteria	Ascomycota	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	D-glucarate catabolic process [GO:0042838]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1jdfb2_d2pa6a1__1			Proteobacteria	Euryarchaeota	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	D-glucarate catabolic process [GO:0042838]	glycolytic process [GO:0006096]		cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1jdfd2_d2xh7b1__1		Fungi	Proteobacteria	Ascomycota	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	D-glucarate catabolic process [GO:0042838]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1jdic__d1dzwp___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]	aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]
d1jdie__d1gt7j___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]
d1jdif__d2v9ia___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]
d1jdsc__d1u1de___1			Crenarchaeota	Proteobacteria	S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]		cytosol [GO:0005829]	S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]
d1jdyb3_d1kfqa3__1	Metazoa		Chordata	Ciliophora	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	glucose metabolic process [GO:0006006]	galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	sarcoplasmic reticulum [GO:0016529]	cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1je6a1_d1s9xb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; natural killer cell lectin-like receptor binding [GO:0046703]; adaptive immune response [GO:0002250]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cytolysis [GO:0019835]; gamma-delta T cell activation [GO:0046629]; immune response-activating cell surface receptor signaling pathway [GO:0002429]; negative regulation of defense response to virus by host [GO:0050689]; regulation of immune response [GO:0050776]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to retinoic acid [GO:0032526]; viral process [GO:0016032]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cytolysis [GO:0019835]; gamma-delta T cell activation [GO:0046629]; immune response-activating cell surface receptor signaling pathway [GO:0002429]; negative regulation of defense response to virus by host [GO:0050689]; regulation of immune response [GO:0050776]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to retinoic acid [GO:0032526]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	natural killer cell lectin-like receptor binding [GO:0046703]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1jeaa__d1sh7a___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; sporulation resulting in formation of a cellular spore [GO:0030435]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1jeca1_d1m8pb1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1jeca2_d1m8pa2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1jeca3_d2ov2e1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cell cortex [GO:0005938]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; calcium-dependent protein binding [GO:0048306]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cerebral cortex GABAergic interneuron development [GO:0021894]; establishment or maintenance of cell polarity [GO:0007163]; homeostasis of number of cells within a tissue [GO:0048873]; intracellular signal transduction [GO:0035556]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of neuron maturation [GO:0014041]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; synaptic transmission, GABAergic [GO:0051932]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cerebral cortex GABAergic interneuron development [GO:0021894]; establishment or maintenance of cell polarity [GO:0007163]; homeostasis of number of cells within a tissue [GO:0048873]; intracellular signal transduction [GO:0035556]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of neuron maturation [GO:0014041]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; synaptic transmission, GABAergic [GO:0051932]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cell cortex [GO:0005938]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	calcium-dependent protein binding [GO:0048306]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein kinase binding [GO:0019901]
d1jeda3_d4lx0a___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	axon [GO:0030424]; cell [GO:0005623]; centriolar satellite [GO:0034451]; cleavage furrow [GO:0032154]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; multivesicular body [GO:0005771]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; postsynaptic recycling endosome [GO:0098837]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; Schaffer collateral - CA1 synapse [GO:0098685]; spindle pole [GO:0000922]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133]; vesicle [GO:0031982]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; microtubule binding [GO:0008017]; myosin V binding [GO:0031489]; syntaxin binding [GO:0019905]; amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; plasma membrane to endosome transport [GO:0048227]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-translational protein modification [GO:0043687]; protein localization to plasma membrane [GO:0072659]; Rab protein signal transduction [GO:0032482]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; renal water homeostasis [GO:0003091]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; plasma membrane to endosome transport [GO:0048227]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-translational protein modification [GO:0043687]; protein localization to plasma membrane [GO:0072659]; Rab protein signal transduction [GO:0032482]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; renal water homeostasis [GO:0003091]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	axon [GO:0030424]; cell [GO:0005623]; centriolar satellite [GO:0034451]; cleavage furrow [GO:0032154]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; multivesicular body [GO:0005771]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; postsynaptic recycling endosome [GO:0098837]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; Schaffer collateral - CA1 synapse [GO:0098685]; spindle pole [GO:0000922]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133]; vesicle [GO:0031982]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; microtubule binding [GO:0008017]; myosin V binding [GO:0031489]; syntaxin binding [GO:0019905]
d1jedb1_d1ze1c1__1	Fungi		Ascomycota	Thermotogae	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	mitochondrion [GO:0005739]; pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]; mRNA pseudouridine synthesis [GO:1990481]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	mRNA pseudouridine synthesis [GO:1990481]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]
d1jeea2_d1xnja2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1jeeb1_d1jhda1__1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1jefa__d5g27a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1jehb2_d1vqwa2__1	Fungi	Fungi	Ascomycota	Ascomycota	cell [GO:0005623]; glycine cleavage complex [GO:0005960]; mitochondrial nucleoid [GO:0042645]; mitochondrial oxoglutarate dehydrogenase complex [GO:0009353]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glycine dehydrogenase (decarboxylating) activity [GO:0004375]; oxoglutarate dehydrogenase (succinyl-transferring) activity [GO:0004591]; pyruvate dehydrogenase activity [GO:0004738]; 2-oxoglutarate metabolic process [GO:0006103]; cell redox homeostasis [GO:0045454]; glycine catabolic process [GO:0006546]; hydrogen peroxide metabolic process [GO:0042743]; isoleucine catabolic process [GO:0006550]; L-serine biosynthetic process [GO:0006564]; leucine catabolic process [GO:0006552]; pyruvate metabolic process [GO:0006090]; valine catabolic process [GO:0006574]	endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; monooxygenase activity [GO:0004497]; N,N-dimethylaniline monooxygenase activity [GO:0004499]; NADP binding [GO:0050661]; protein folding in endoplasmic reticulum [GO:0034975]	2-oxoglutarate metabolic process [GO:0006103]; cell redox homeostasis [GO:0045454]; glycine catabolic process [GO:0006546]; hydrogen peroxide metabolic process [GO:0042743]; isoleucine catabolic process [GO:0006550]; leucine catabolic process [GO:0006552]; L-serine biosynthetic process [GO:0006564]; pyruvate metabolic process [GO:0006090]; valine catabolic process [GO:0006574]	protein folding in endoplasmic reticulum [GO:0034975]	cell [GO:0005623]; glycine cleavage complex [GO:0005960]; mitochondrial nucleoid [GO:0042645]; mitochondrial oxoglutarate dehydrogenase complex [GO:0009353]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]	endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glycine dehydrogenase (decarboxylating) activity [GO:0004375]; oxoglutarate dehydrogenase (succinyl-transferring) activity [GO:0004591]; pyruvate dehydrogenase activity [GO:0004738]	flavin adenine dinucleotide binding [GO:0050660]; monooxygenase activity [GO:0004497]; N,N-dimethylaniline monooxygenase activity [GO:0004499]; NADP binding [GO:0050661]
d1jepa__d4doib___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chalcone isomerase activity [GO:0045430]; flavonoid biosynthetic process [GO:0009813]	chloroplast [GO:0009507]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extrinsic component of endoplasmic reticulum membrane [GO:0042406]; nucleus [GO:0005634]; plant-type vacuole membrane [GO:0009705]; chalcone isomerase activity [GO:0045430]; flavonoid biosynthetic process [GO:0009813]; response to auxin [GO:0009733]; response to karrikin [GO:0080167]; response to UV [GO:0009411]; response to UV-B [GO:0010224]	flavonoid biosynthetic process [GO:0009813]	flavonoid biosynthetic process [GO:0009813]; response to auxin [GO:0009733]; response to karrikin [GO:0080167]; response to UV [GO:0009411]; response to UV-B [GO:0010224]		chloroplast [GO:0009507]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extrinsic component of endoplasmic reticulum membrane [GO:0042406]; nucleus [GO:0005634]; plant-type vacuole membrane [GO:0009705]	chalcone isomerase activity [GO:0045430]	chalcone isomerase activity [GO:0045430]
d1jeta__d2klfa___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	protein transport [GO:0015031]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	peptide transmembrane transporter activity [GO:1904680]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1jeua__d5m8hg___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	cytoplasm [GO:0005737]; histidine biosynthetic process [GO:0000105]	protein transport [GO:0015031]	histidine biosynthetic process [GO:0000105]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]	peptide transmembrane transporter activity [GO:1904680]	
d1jexa__d2i89d___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; response to cadmium ion [GO:0046686]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	response to cadmium ion [GO:0046686]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]	electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1jeyb1_d1jeqa3__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; Ku70:Ku80 complex [GO:0043564]; membrane [GO:0016020]; nonhomologous end joining complex [GO:0070419]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; site of DNA damage [GO:0090734]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA end binding [GO:0045027]; DNA helicase activity [GO:0003678]; double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; protein C-terminus binding [GO:0008022]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; activation of innate immune response [GO:0002218]; brain development [GO:0007420]; cell population proliferation [GO:0008283]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to fatty acid [GO:0071398]; cellular response to gamma radiation [GO:0071480]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to X-ray [GO:0071481]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; establishment of integrated proviral latency [GO:0075713]; hematopoietic stem cell differentiation [GO:0060218]; innate immune response [GO:0045087]; negative regulation of t-circle formation [GO:1904430]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil degranulation [GO:0043312]; positive regulation of catalytic activity [GO:0043085]; positive regulation of neurogenesis [GO:0050769]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of type I interferon production [GO:0032481]; protein localization to chromosome, telomeric region [GO:0070198]; regulation of smooth muscle cell proliferation [GO:0048660]; regulation of telomere maintenance [GO:0032204]; response to drug [GO:0042493]; telomere maintenance [GO:0000723]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Ku70:Ku80 complex [GO:0043564]; membrane [GO:0016020]; nonhomologous end joining complex [GO:0070419]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; site of DNA damage [GO:0090734]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA end binding [GO:0045027]; DNA helicase activity [GO:0003678]; double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; protein C-terminus binding [GO:0008022]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; activation of innate immune response [GO:0002218]; brain development [GO:0007420]; cell population proliferation [GO:0008283]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to fatty acid [GO:0071398]; cellular response to gamma radiation [GO:0071480]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to X-ray [GO:0071481]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; establishment of integrated proviral latency [GO:0075713]; hematopoietic stem cell differentiation [GO:0060218]; innate immune response [GO:0045087]; negative regulation of t-circle formation [GO:1904430]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil degranulation [GO:0043312]; positive regulation of catalytic activity [GO:0043085]; positive regulation of neurogenesis [GO:0050769]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of type I interferon production [GO:0032481]; protein localization to chromosome, telomeric region [GO:0070198]; regulation of smooth muscle cell proliferation [GO:0048660]; regulation of telomere maintenance [GO:0032204]; response to drug [GO:0042493]; telomere maintenance [GO:0000723]	activation of innate immune response [GO:0002218]; brain development [GO:0007420]; cell population proliferation [GO:0008283]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to fatty acid [GO:0071398]; cellular response to gamma radiation [GO:0071480]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to X-ray [GO:0071481]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; establishment of integrated proviral latency [GO:0075713]; hematopoietic stem cell differentiation [GO:0060218]; innate immune response [GO:0045087]; negative regulation of t-circle formation [GO:1904430]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil degranulation [GO:0043312]; positive regulation of catalytic activity [GO:0043085]; positive regulation of neurogenesis [GO:0050769]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of type I interferon production [GO:0032481]; protein localization to chromosome, telomeric region [GO:0070198]; regulation of smooth muscle cell proliferation [GO:0048660]; regulation of telomere maintenance [GO:0032204]; response to drug [GO:0042493]; telomere maintenance [GO:0000723]	activation of innate immune response [GO:0002218]; brain development [GO:0007420]; cell population proliferation [GO:0008283]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to fatty acid [GO:0071398]; cellular response to gamma radiation [GO:0071480]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to X-ray [GO:0071481]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; establishment of integrated proviral latency [GO:0075713]; hematopoietic stem cell differentiation [GO:0060218]; innate immune response [GO:0045087]; negative regulation of t-circle formation [GO:1904430]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil degranulation [GO:0043312]; positive regulation of catalytic activity [GO:0043085]; positive regulation of neurogenesis [GO:0050769]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of type I interferon production [GO:0032481]; protein localization to chromosome, telomeric region [GO:0070198]; regulation of smooth muscle cell proliferation [GO:0048660]; regulation of telomere maintenance [GO:0032204]; response to drug [GO:0042493]; telomere maintenance [GO:0000723]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Ku70:Ku80 complex [GO:0043564]; membrane [GO:0016020]; nonhomologous end joining complex [GO:0070419]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; site of DNA damage [GO:0090734]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Ku70:Ku80 complex [GO:0043564]; membrane [GO:0016020]; nonhomologous end joining complex [GO:0070419]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; site of DNA damage [GO:0090734]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA end binding [GO:0045027]; DNA helicase activity [GO:0003678]; double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA end binding [GO:0045027]; DNA helicase activity [GO:0003678]; double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]
d1jf1a2_d2bsra2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1jf1a2_d3qiua1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1jf1b2_d1bogb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1jf1b2_d1inqa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1jf2a__d2otgc___1	Metazoa	Metazoa	Cnidaria	Mollusca	calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]	myosin complex [GO:0016459]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	bioluminescence [GO:0008218]			myosin complex [GO:0016459]	calcium ion binding [GO:0005509]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]
d1jf5a1_d1smab1__1			Firmicutes	Deinococcus-Thermus	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]
d1jf5a2_d1xh1a1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1jf5a3_d4x0vd___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1jf5b1_d5e6ya1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1jf5b3_d2f2hf4__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1jf6a1_d3jv4c___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	carbohydrate metabolic process [GO:0005975]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]		centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d1jf6a2_d3wema3__1		Viridiplantae	Firmicutes	Streptophyta	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]	carbohydrate metabolic process [GO:0005975]				metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]
d1jf6a3_d3bsha1__1		Viridiplantae	Firmicutes	Streptophyta	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular space [GO:0005615]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1jf6b2_d1xsif3__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1jfda__d3fq3h___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1jffb2_d5yl4a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]; tubulin binding [GO:0015631]; microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]	microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	cytoplasm [GO:0005737]; microtubule [GO:0005874]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; structural constituent of cytoskeleton [GO:0005200]	tubulin binding [GO:0015631]
d1jfga__d1ubxa___1	Fungi	Metazoa	Ascomycota	Chordata	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	cytoplasm [GO:0005737]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	sesquiterpenoid biosynthetic process [GO:0016106]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]
d1jfha2_d2cera___1	Metazoa		Chordata	Crenarchaeota	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]
d1jfic1_d1qn3a2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714]; negative regulation of transcription by RNA polymerase II [GO:0000122]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	negative regulation of transcription by RNA polymerase II [GO:0000122]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleus [GO:0005634]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1jfqh1_d1im9b2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1jfqh1_d1oaxh___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1jfqh2_d1ls0b6__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1jfql1_d2ojzi1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	metal ion binding [GO:0046872]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d1jfql2_d1jptl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1jfta2_d3h5vb___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]; negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cytosol [GO:0005829]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1jg0a__d1i00a___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1jg9a1_d3l4va3__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	carbohydrate metabolic process [GO:0005975]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	amylosucrase activity [GO:0047669]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]
d1jgcb__d3is8l___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1jgcb__d5da5y___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]
d1jgcc__d2yw7i1__1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1jgda1_d6b0sl1__1	Metazoa		Chordata	Apicomplexa	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1jgea1_d1q9oa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1jgea2_d2g9ha2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1jgeb1_d5cbac___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]
d1jgfa__d1ebkd___1						host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1jgfb__d2q54b___1						aspartic-type endopeptidase activity [GO:0004190]						aspartic-type endopeptidase activity [GO:0004190]
d1jgll1_d5v7ul2__1	Metazoa		Chordata									
d1jgvh1_d4olul2__1	Metazoa		Chordata			host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1jh1a__d3hy7b___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]
d1jh1a__d3uvca___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1jh2a__d1sx4o___1				Proteobacteria		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d1jh2i__d1sx4q___1				Proteobacteria		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d1jh3a__d1h3fa2__1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]; tyrosine-tRNA ligase activity [GO:0004831]; regulation of protein complex stability [GO:0061635]; tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	regulation of protein complex stability [GO:0061635]; tyrosyl-tRNA aminoacylation [GO:0006437]	tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]; tyrosine-tRNA ligase activity [GO:0004831]	ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]
d1jh5f__d4qpya___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	collagen trimer [GO:0005581]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	collagen trimer [GO:0005581]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	identical protein binding [GO:0042802]
d1jh5g__d5hbaa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	complement activation, classical pathway [GO:0006958]; protein homotrimerization [GO:0070207]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	complement activation, classical pathway [GO:0006958]; protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]		cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	
d1jh6b__d5ldia___1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; cyclic nucleotide metabolic process [GO:0009187]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; 2'-5'-RNA ligase activity [GO:0008664]; ATP binding [GO:0005524]	cyclic nucleotide metabolic process [GO:0009187]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; 2'-5'-RNA ligase activity [GO:0008664]; ATP binding [GO:0005524]
d1jhfa2_d1kcag___1			Proteobacteria		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]; transcription, DNA-templated [GO:0006351]	virion [GO:0019012]; core promoter binding [GO:0001047]; identical protein binding [GO:0042802]; latency-replication decision [GO:0098689]; maintenance of viral latency [GO:0019044]; negative regulation of transcription by competitive promoter binding [GO:0010944]; positive regulation of viral transcription [GO:0050434]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]; transcription, DNA-templated [GO:0006351]	latency-replication decision [GO:0098689]; maintenance of viral latency [GO:0019044]; negative regulation of transcription by competitive promoter binding [GO:0010944]; positive regulation of viral transcription [GO:0050434]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	virion [GO:0019012]	DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	core promoter binding [GO:0001047]; identical protein binding [GO:0042802]
d1jhja__d1jz0g3__1	Metazoa		Chordata		anaphase-promoting complex [GO:0005680]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell cycle [GO:0007049]; cell division [GO:0051301]; protein K11-linked ubiquitination [GO:0070979]; regulation of mitotic cell cycle phase transition [GO:1901990]; ubiquitin-dependent protein catabolic process [GO:0006511]		anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell cycle [GO:0007049]; cell division [GO:0051301]; protein K11-linked ubiquitination [GO:0070979]; regulation of mitotic cell cycle phase transition [GO:1901990]; ubiquitin-dependent protein catabolic process [GO:0006511]		anaphase-promoting complex [GO:0005680]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]			
d1jhkl1_d4tuob2__1	Metazoa		Chordata									
d1jhlh1_d3c6se2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1jhll__d2agjh1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]		cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]		extracellular region [GO:0005576]		lysozyme activity [GO:0003796]	
d1ji1a3_d1j0hb3__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1ji1b3_d3gxia2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1ji2a3_d5g3rb1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]
d1ji4d__d4to9p___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1ji4f__d4toau___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1ji4h__d4todd___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1ji4i__d4bmub___1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1ji5a__d1jkud___1			Firmicutes	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]
d1ji5c__d3oj5n___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d1ji5c__d5d8xw___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1ji5d__d2j2fc___1		Viridiplantae	Firmicutes	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]; cytoplasm [GO:0005737]	chloroplast [GO:0009507]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d1ji6a1_d1i5pa1__1			Firmicutes	Firmicutes	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]			signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d1ji6a1_d1px4b3__1			Firmicutes	Proteobacteria	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	sporulation resulting in formation of a cellular spore [GO:0030435]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1ji6a2_d1ciya2__1			Firmicutes	Firmicutes	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]			signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d1ji6a2_d3eb7b2__1			Firmicutes	Firmicutes	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]			signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d1jiba1_d5wszb___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]	carbohydrate metabolic process [GO:0005975]				metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d1jibb3_d1i75b4__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1jibb3_d5g3ra1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]
d1jida__d2v3cb___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; nucleolus [GO:0005730]; signal recognition particle [GO:0048500]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]; 7S RNA binding [GO:0008312]; RNA binding [GO:0003723]; cotranslational protein targeting to membrane [GO:0006613]; response to drug [GO:0042493]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition [GO:0006617]	signal recognition particle, endoplasmic reticulum targeting [GO:0005786]; 7S RNA binding [GO:0008312]; SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition [GO:0006617]	cotranslational protein targeting to membrane [GO:0006613]; response to drug [GO:0042493]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition [GO:0006617]	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition [GO:0006617]	cytosol [GO:0005829]; nucleolus [GO:0005730]; signal recognition particle [GO:0048500]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]	signal recognition particle, endoplasmic reticulum targeting [GO:0005786]	7S RNA binding [GO:0008312]; RNA binding [GO:0003723]	7S RNA binding [GO:0008312]
d1jifa__d4jh8b___1			Actinobacteria	Firmicutes	drug binding [GO:0008144]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]	drug binding [GO:0008144]	magnesium ion binding [GO:0000287]; transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]
d1jigb__d3uoij___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1jigd__d3hx5u1__1			Firmicutes		cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	
d1jiha1_d2au0a1__1	Fungi		Ascomycota	Crenarchaeota	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d1jihb1_d2agqa1__1	Fungi		Ascomycota	Crenarchaeota	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d1jika__d2quha2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; kinase inhibitor activity [GO:0019210]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tryptophan-tRNA ligase activity [GO:0004830]; angiogenesis [GO:0001525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; regulation of angiogenesis [GO:0045765]; regulation of protein ADP-ribosylation [GO:0010835]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]	tyrosyl-tRNA aminoacylation [GO:0006437]	angiogenesis [GO:0001525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; regulation of angiogenesis [GO:0045765]; regulation of protein ADP-ribosylation [GO:0010835]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]	ATP binding [GO:0005524]; kinase inhibitor activity [GO:0019210]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tryptophan-tRNA ligase activity [GO:0004830]
d1jima__d3sv7a1__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1jina__d2hpda___1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; erythromycin biosynthetic process [GO:1901115]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	erythromycin biosynthetic process [GO:1901115]; oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d1jiqa__d1u0fb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d1jiqc__d1jxac1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytosol [GO:0005829]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]
d1jira__d1agja___1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]
d1jiwi__d1smpi___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; metalloendopeptidase inhibitor activity [GO:0008191]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; pathogenesis [GO:0009405]; proteolysis [GO:0006508]		pathogenesis [GO:0009405]; proteolysis [GO:0006508]	periplasmic space [GO:0042597]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metalloendopeptidase inhibitor activity [GO:0008191]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1jiwp2_d5d3ca___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metalloendopeptidase inhibitor activity [GO:0008191]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	periplasmic space [GO:0042597]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	metalloendopeptidase inhibitor activity [GO:0008191]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1jixa__d2acva___1		Viridiplantae		Streptophyta	DNA beta-glucosyltransferase activity [GO:0033821]; DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]	intracellular membrane-bounded organelle [GO:0043231]; nucleotide binding [GO:0000166]; transferase activity, transferring hexosyl groups [GO:0016758]; UDP-glycosyltransferase activity [GO:0008194]	DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]			intracellular membrane-bounded organelle [GO:0043231]	DNA beta-glucosyltransferase activity [GO:0033821]	nucleotide binding [GO:0000166]; transferase activity, transferring hexosyl groups [GO:0016758]; UDP-glycosyltransferase activity [GO:0008194]
d1jiya__d4w55a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1jiza1_d3p7we___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1jj1a__d158la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1jj2e1_d1vq5e2__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1jj2l__d1vq5m1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1jj2m__d1yl4n1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1jj2r__d2hgqw1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1jj2s__d1yl3u1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1jjac__d1hg0d___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]; asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]	asparaginase activity [GO:0004067]; asparagine metabolic process [GO:0006528]	asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]	asparagine metabolic process [GO:0006528]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]	asparaginase activity [GO:0004067]
d1jjic__d5tnqd___1			Euryarchaeota	Proteobacteria	hydrolase activity [GO:0016787]	hydrolase activity [GO:0016787]					hydrolase activity [GO:0016787]	hydrolase activity [GO:0016787]
d1jjja__d2lbaa1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]; epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	lipid binding [GO:0008289]	epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]		azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]		fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]	lipid binding [GO:0008289]
d1jjta__d2ohid1__1			Proteobacteria	Euryarchaeota	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]				beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1jjtb__d5ni0a___1			Proteobacteria	Proteobacteria	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]				beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1jjua3_d1ramb1__1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]
d1jjua5_d1jmza5__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1jjwa__d3hyez___1		Fungi	Proteobacteria	Ascomycota	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1jjwc__d5l6bn___1		Fungi	Proteobacteria	Ascomycota	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1jjxa__d4getb___1	Metazoa	Metazoa	Chordata	Arthropoda	cell periphery [GO:0071944]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; lipid binding [GO:0008289]; cell proliferation in forebrain [GO:0021846]; epithelial cell proliferation [GO:0050673]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]; triglyceride catabolic process [GO:0019433]	histamine binding [GO:0051381]; nitric oxide binding [GO:0070026]	cell proliferation in forebrain [GO:0021846]; epithelial cell proliferation [GO:0050673]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]; triglyceride catabolic process [GO:0019433]		cell-cell junction [GO:0005911]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]		lipid binding [GO:0008289]	histamine binding [GO:0051381]; nitric oxide binding [GO:0070026]
d1jk3a__d1z3ja2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1jk7a__d2z06c___1	Metazoa		Chordata	Deinococcus-Thermus	cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; protein-containing complex [GO:0032991]; PTW/PP1 phosphatase complex [GO:0072357]; lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]	metal ion binding [GO:0046872]	cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]		cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]		lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]	metal ion binding [GO:0046872]
d1jk8a1_d3q1sl2__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; secretory granule lumen [GO:0034774]; transport vesicle [GO:0030133]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; insulin-like growth factor receptor binding [GO:0005159]; protease binding [GO:0002020]; activation of protein kinase B activity [GO:0032148]; acute-phase response [GO:0006953]; alpha-beta T cell activation [GO:0046631]; cell-cell signaling [GO:0007267]; cellular protein metabolic process [GO:0044267]; cognition [GO:0050890]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fatty acid homeostasis [GO:0055089]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of fatty acid metabolic process [GO:0045922]; negative regulation of feeding behavior [GO:2000252]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of glycogen catabolic process [GO:0045818]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of protein secretion [GO:0050709]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; neuron projection maintenance [GO:1990535]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of respiratory burst [GO:0060267]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of protein localization [GO:0032880]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein secretion [GO:0050708]; regulation of synaptic plasticity [GO:0048167]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transmembrane transporter activity [GO:0022898]; wound healing [GO:0042060]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]; acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	activation of protein kinase B activity [GO:0032148]; acute-phase response [GO:0006953]; alpha-beta T cell activation [GO:0046631]; cell-cell signaling [GO:0007267]; cellular protein metabolic process [GO:0044267]; cognition [GO:0050890]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fatty acid homeostasis [GO:0055089]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; G protein-coupled receptor signaling pathway [GO:0007186]; insulin receptor signaling pathway [GO:0008286]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of fatty acid metabolic process [GO:0045922]; negative regulation of feeding behavior [GO:2000252]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of glycogen catabolic process [GO:0045818]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of protein secretion [GO:0050709]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; neuron projection maintenance [GO:1990535]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of respiratory burst [GO:0060267]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of protein localization [GO:0032880]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein secretion [GO:0050708]; regulation of synaptic plasticity [GO:0048167]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transmembrane transporter activity [GO:0022898]; wound healing [GO:0042060]	acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; secretory granule lumen [GO:0034774]; transport vesicle [GO:0030133]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; protease binding [GO:0002020]	cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]
d1jk8b1_d2yssb1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; secretory granule lumen [GO:0034774]; transport vesicle [GO:0030133]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; insulin-like growth factor receptor binding [GO:0005159]; protease binding [GO:0002020]; activation of protein kinase B activity [GO:0032148]; acute-phase response [GO:0006953]; alpha-beta T cell activation [GO:0046631]; cell-cell signaling [GO:0007267]; cellular protein metabolic process [GO:0044267]; cognition [GO:0050890]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fatty acid homeostasis [GO:0055089]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of fatty acid metabolic process [GO:0045922]; negative regulation of feeding behavior [GO:2000252]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of glycogen catabolic process [GO:0045818]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of protein secretion [GO:0050709]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; neuron projection maintenance [GO:1990535]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of respiratory burst [GO:0060267]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of protein localization [GO:0032880]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein secretion [GO:0050708]; regulation of synaptic plasticity [GO:0048167]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transmembrane transporter activity [GO:0022898]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	activation of protein kinase B activity [GO:0032148]; acute-phase response [GO:0006953]; alpha-beta T cell activation [GO:0046631]; cell-cell signaling [GO:0007267]; cellular protein metabolic process [GO:0044267]; cognition [GO:0050890]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fatty acid homeostasis [GO:0055089]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; G protein-coupled receptor signaling pathway [GO:0007186]; insulin receptor signaling pathway [GO:0008286]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of fatty acid metabolic process [GO:0045922]; negative regulation of feeding behavior [GO:2000252]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of glycogen catabolic process [GO:0045818]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of protein secretion [GO:0050709]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; neuron projection maintenance [GO:1990535]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of respiratory burst [GO:0060267]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of protein localization [GO:0032880]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein secretion [GO:0050708]; regulation of synaptic plasticity [GO:0048167]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transmembrane transporter activity [GO:0022898]; wound healing [GO:0042060]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; secretory granule lumen [GO:0034774]; transport vesicle [GO:0030133]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; protease binding [GO:0002020]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1jk8b2_d4p4rc1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; secretory granule lumen [GO:0034774]; transport vesicle [GO:0030133]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; insulin-like growth factor receptor binding [GO:0005159]; protease binding [GO:0002020]; activation of protein kinase B activity [GO:0032148]; acute-phase response [GO:0006953]; alpha-beta T cell activation [GO:0046631]; cell-cell signaling [GO:0007267]; cellular protein metabolic process [GO:0044267]; cognition [GO:0050890]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fatty acid homeostasis [GO:0055089]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of fatty acid metabolic process [GO:0045922]; negative regulation of feeding behavior [GO:2000252]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of glycogen catabolic process [GO:0045818]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of protein secretion [GO:0050709]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; neuron projection maintenance [GO:1990535]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of respiratory burst [GO:0060267]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of protein localization [GO:0032880]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein secretion [GO:0050708]; regulation of synaptic plasticity [GO:0048167]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transmembrane transporter activity [GO:0022898]; wound healing [GO:0042060]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	activation of protein kinase B activity [GO:0032148]; acute-phase response [GO:0006953]; alpha-beta T cell activation [GO:0046631]; cell-cell signaling [GO:0007267]; cellular protein metabolic process [GO:0044267]; cognition [GO:0050890]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fatty acid homeostasis [GO:0055089]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; G protein-coupled receptor signaling pathway [GO:0007186]; insulin receptor signaling pathway [GO:0008286]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of fatty acid metabolic process [GO:0045922]; negative regulation of feeding behavior [GO:2000252]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of glycogen catabolic process [GO:0045818]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of protein secretion [GO:0050709]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; neuron projection maintenance [GO:1990535]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of respiratory burst [GO:0060267]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of protein localization [GO:0032880]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein secretion [GO:0050708]; regulation of synaptic plasticity [GO:0048167]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transmembrane transporter activity [GO:0022898]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; secretory granule lumen [GO:0034774]; transport vesicle [GO:0030133]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; protease binding [GO:0002020]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d1jkca__d1ge2a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1jkda__d1bb5b___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1jkia2_d2pkrr2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; inositol-3-phosphate synthase activity [GO:0004512]; inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]	inositol-3-phosphate synthase activity [GO:0004512]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1jkib2_d1cerp2__1	Fungi		Ascomycota	Deinococcus-Thermus	cytoplasm [GO:0005737]; inositol-3-phosphate synthase activity [GO:0004512]; inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	inositol-3-phosphate synthase activity [GO:0004512]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1jkmb__d1zixa___1			Firmicutes	Proteobacteria	hydrolase activity [GO:0016787]	carboxymethylenebutenolidase activity [GO:0008806]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			hydrolase activity [GO:0016787]	carboxymethylenebutenolidase activity [GO:0008806]
d1jkna1_d3gwyb1__1	Viridiplantae		Streptophyta	Bacteroidetes	chloroplast [GO:0009507]; bis(5'-adenosyl)-pentaphosphatase activity [GO:0034432]; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]; guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity [GO:0008893]; nucleoside phosphate metabolic process [GO:0006753]	hydrolase activity [GO:0016787]	nucleoside phosphate metabolic process [GO:0006753]		chloroplast [GO:0009507]		bis(5'-adenosyl)-pentaphosphatase activity [GO:0034432]; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]; guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity [GO:0008893]	hydrolase activity [GO:0016787]
d1jkue__d4dyuh___1			Firmicutes	Proteobacteria	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	cell [GO:0005623]; cytoplasm [GO:0005737]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]		cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]		cell [GO:0005623]; cytoplasm [GO:0005737]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1jkuf__d1fz9c___1			Firmicutes	Proteobacteria	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]		cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]			catalase activity [GO:0004096]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1jkvb__d1xu5c___1			Firmicutes	Proteobacteria	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]		cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]			catalase activity [GO:0004096]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1jkvf__d3qvdf1__1			Firmicutes	Euryarchaeota	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]					catalase activity [GO:0004096]; metal ion binding [GO:0046872]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1jkwa2_d4or5b1__1	Metazoa	Metazoa	Chordata	Chordata	cyclin-dependent protein kinase activating kinase holoenzyme complex [GO:0019907]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIIH holo complex [GO:0005675]; transcription factor TFIIK complex [GO:0070985]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; 7-methylguanosine mRNA capping [GO:0006370]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein stabilization [GO:0050821]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase I promoter [GO:0006361]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription-coupled nucleotide-excision repair [GO:0006283]	ELL-EAF complex [GO:0032783]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription elongation factor complex [GO:0008023]; transcriptionally active chromatin [GO:0035327]; DNA-binding transcription factor activity [GO:0003700]; double-stranded DNA binding [GO:0003690]; spermatid development [GO:0007286]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	7-methylguanosine mRNA capping [GO:0006370]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein stabilization [GO:0050821]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]	spermatid development [GO:0007286]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cyclin-dependent protein kinase activating kinase holoenzyme complex [GO:0019907]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor TFIIH holo complex [GO:0005675]; transcription factor TFIIK complex [GO:0070985]	ELL-EAF complex [GO:0032783]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; transcription elongation factor complex [GO:0008023]	cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]	DNA-binding transcription factor activity [GO:0003700]; double-stranded DNA binding [GO:0003690]
d1jkxd__d5uaid1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]	cytosol [GO:0005829]; methionyl-tRNA formyltransferase activity [GO:0004479]; conversion of methionyl-tRNA to N-formyl-methionyl-tRNA [GO:0071951]; regulation of transmembrane transporter activity [GO:0022898]	'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA [GO:0071951]; regulation of transmembrane transporter activity [GO:0022898]	cytosol [GO:0005829]	cytosol [GO:0005829]	phosphoribosylglycinamide formyltransferase activity [GO:0004644]	methionyl-tRNA formyltransferase activity [GO:0004479]
d1jkya1_d4dv8a2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d1jl2a__d3p83f___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d1jl3b__d1lk0a___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; arsenate reductase (thioredoxin) activity [GO:0030612]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]	cytoplasm [GO:0005737]; arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]	response to arsenic-containing substance [GO:0046685]	response to arsenic-containing substance [GO:0046685]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arsenate reductase (thioredoxin) activity [GO:0030612]; protein tyrosine phosphatase activity [GO:0004725]	arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]
d1jl3b__d4d74a1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; arsenate reductase (thioredoxin) activity [GO:0030612]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]	protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]; polysaccharide biosynthetic process [GO:0000271]	response to arsenic-containing substance [GO:0046685]	pathogenesis [GO:0009405]; polysaccharide biosynthetic process [GO:0000271]	cytoplasm [GO:0005737]		arsenate reductase (thioredoxin) activity [GO:0030612]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d1jl4a1_d4l8sa1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1jl4b2_d1onqa2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1jl4d1_d6azzb2__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1jl6a__d3wcvf___1	Metazoa	Metazoa	Annelida	Annelida	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1jl8a1_d1t2xa1__1		Fungi	Firmicutes	Ascomycota	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]			extracellular region [GO:0005576]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]
d1jl8a2_d1ua7a1__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d1jl8a3_d4nrrb1__1		Fungi	Firmicutes	Mucoromycota	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	beta-mannosidase activity [GO:0004567]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]	metabolic process [GO:0008152]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	beta-mannosidase activity [GO:0004567]
d1jl8b3_d1cxka4__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1jlba1_d5j1ec2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1jldb__d1xe5b___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1jldb__d3s56a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]
d1jlga1_d4i2pa2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1jlha__d5lu5c___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]
d1jlhc__d4em6c___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	glucose-6-phosphate isomerase activity [GO:0004347]
d1jlja__d1t3eb3__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin cofactor binding [GO:0043546]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; response to metal ion [GO:0010038]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; response to metal ion [GO:0010038]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin cofactor binding [GO:0043546]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]
d1jlka__d3tmya___1			Cyanobacteria	Thermotogae	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]		cytoplasm [GO:0005737]		metal ion binding [GO:0046872]
d1jlkb__d3dgec___1			Cyanobacteria	Thermotogae	phosphorelay signal transduction system [GO:0000160]	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; protein autophosphorylation [GO:0046777]	phosphorelay signal transduction system [GO:0000160]	protein autophosphorylation [GO:0046777]		integral component of plasma membrane [GO:0005887]		ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d1jllb2_d2nu9e2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d1jlld1_d4a26a2__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; kinetoplast [GO:0020023]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; tetrahydrofolate interconversion [GO:0035999]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cytosol [GO:0005829]; kinetoplast [GO:0020023]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]
d1jlle1_d3ufxa2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]		cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]
d1jlle2_d1jkje2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d1jlma__d1sq0a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d1jlna1_d1ikza___1	Metazoa		Chordata		cell junction [GO:0030054]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; ERBB2 signaling pathway [GO:0038128]; in utero embryonic development [GO:0001701]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; protein dephosphorylation [GO:0006470]		ERBB2 signaling pathway [GO:0038128]; in utero embryonic development [GO:0001701]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; protein dephosphorylation [GO:0006470]		cell junction [GO:0030054]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]	
d1jlna1_d1lqfa1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; ERBB2 signaling pathway [GO:0038128]; in utero embryonic development [GO:0001701]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; protein dephosphorylation [GO:0006470]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	ERBB2 signaling pathway [GO:0038128]; in utero embryonic development [GO:0001701]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; protein dephosphorylation [GO:0006470]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cell junction [GO:0030054]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1jlra__d4ohcd___1			Apicomplexa	Proteobacteria	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	magnesium ion binding [GO:0000287]; orotate phosphoribosyltransferase activity [GO:0004588]; 'de novo' UMP biosynthetic process [GO:0044205]; nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	'de novo' UMP biosynthetic process [GO:0044205]; nucleoside metabolic process [GO:0009116]			GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]	magnesium ion binding [GO:0000287]; orotate phosphoribosyltransferase activity [GO:0004588]
d1jlvc1_d2hqtf2__1	Metazoa	Fungi	Arthropoda	Ascomycota	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]; enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]; positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]		positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]	glutathione transferase activity [GO:0004364]	enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]
d1jlvc2_d3ktla1__1	Metazoa	Metazoa	Arthropoda	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione transferase activity [GO:0004364]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1jlvd1_d4q5fd2__1	Metazoa	Metazoa	Arthropoda	Nematoda (roundworms)	glutathione transferase activity [GO:0004364]	brush border [GO:0005903]; cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; cellular oxidant detoxification [GO:0098869]; oxidation-reduction process [GO:0055114]		cellular oxidant detoxification [GO:0098869]; oxidation-reduction process [GO:0055114]		brush border [GO:0005903]; cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]
d1jlvd2_d1c72a2__1	Metazoa	Metazoa	Arthropoda	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytosol [GO:0005829]; intercellular bridge [GO:0045171]	glutathione transferase activity [GO:0004364]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d1jlve1_d2gdrb2__1	Metazoa		Arthropoda	Proteobacteria	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]					glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1jlvf1_d6gsvb1__1	Metazoa	Metazoa	Arthropoda	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]		glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]		cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	glutathione transferase activity [GO:0004364]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d1jlvf2_d1vf2b1__1	Metazoa	Metazoa	Arthropoda	Chordata	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1jm1a__d1nu1e1__1		Metazoa	Crenarchaeota	Chordata	membrane [GO:0016020]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	membrane [GO:0016020]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1jmaa__d1zvoa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine binding [GO:0019955]; tumor necrosis factor-activated receptor activity [GO:0005031]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of adaptive immune memory response [GO:1905675]; negative regulation of alpha-beta T cell proliferation [GO:0046642]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell migration [GO:2000406]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of adaptive immune memory response [GO:1905675]; negative regulation of alpha-beta T cell proliferation [GO:0046642]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell migration [GO:2000406]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytokine binding [GO:0019955]; tumor necrosis factor-activated receptor activity [GO:0005031]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1jmca2_d1k8ga2__1	Metazoa		Chordata	Ciliophora	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]; damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	telomere capping [GO:0016233]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1jmca2_d2qbjq1__1	Metazoa		Chordata		DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]; damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]		base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]		DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]		damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]	
d1jmia__d3ob7a___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	thymidylate synthase activity [GO:0004799]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1jmrb4_d1tf1a1__1				Proteobacteria		cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]		cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]		cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]
d1jmza3_d2cxga1__1			Proteobacteria	Firmicutes	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1jn0o2_d1j0xo2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; GAIT complex [GO:0097452]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; microtubule cytoskeleton organization [GO:0000226]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; protein stabilization [GO:0050821]; regulation of translation [GO:0006417]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; microtubule cytoskeleton organization [GO:0000226]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; protein stabilization [GO:0050821]; regulation of translation [GO:0006417]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; GAIT complex [GO:0097452]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]
d1jn1b__d3t80d1__1			Proteobacteria	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d1jn5a__d5hgra2__1	Metazoa		Chordata	Cyanobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	phycobilisome [GO:0030089]; chloride ion binding [GO:0031404]; light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	phycobilisome [GO:0030089]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	chloride ion binding [GO:0031404]
d1jn6a1_d1kn2l2__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1jn6a2_d3wiim1__1	Metazoa		Chordata									
d1jn6b1_d2c1oa1__1	Metazoa	Metazoa	Chordata	Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d1jn6b2_d1bwma1__1	Metazoa	Metazoa	Chordata	Chordata								
d1jnca__d160la___1						host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]
d1jncb1_d2agdc___1		Metazoa		Chordata		azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]		alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1jncc__d5jwwa___1						host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]
d1jncd__d1iind___1				Proteobacteria		glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]				glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]
d1jnfa1_d1nnta___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular space [GO:0005615]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	cellular iron ion homeostasis [GO:0006879]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; extracellular space [GO:0005615]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]
d1jnhb1_d3tnml1__1	Metazoa		Chordata		plasma membrane [GO:0005886]				plasma membrane [GO:0005886]			
d1jnhc2_d2vxsm1__1	Metazoa	Metazoa	Chordata	Chordata	plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cell-cell signaling [GO:0007267]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]		apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cell death [GO:0008219]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]
d1jnhd1_d12e8l1__1	Metazoa		Chordata		plasma membrane [GO:0005886]				plasma membrane [GO:0005886]			
d1jnhd2_d5v4mg2__1	Metazoa	Metazoa	Chordata	Chordata	plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d1jnhe1_d2seba1__1	Metazoa	Metazoa	Chordata	Chordata	plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d1jnhe2_d3sdxf2__1	Metazoa	Metazoa	Chordata	Chordata	plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1jnhf1_d5jyld2__1	Metazoa	Metazoa	Chordata	Chordata	plasma membrane [GO:0005886]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]		adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	plasma membrane [GO:0005886]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d1jnhg1_d1onqc1__1	Metazoa	Metazoa	Chordata	Chordata	plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1jnhh1_d1q9ob2__1	Metazoa	Metazoa	Chordata	Chordata	plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1jnhh2_d5gs1f2__1	Metazoa		Chordata		plasma membrane [GO:0005886]				plasma membrane [GO:0005886]			
d1jnja1_d5vl3f2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; carbohydrate binding [GO:0030246]; CD4 receptor binding [GO:0042609]; IgM binding [GO:0001791]; protein phosphatase binding [GO:0019903]; sialic acid binding [GO:0033691]; signaling receptor binding [GO:0005102]; B cell activation [GO:0042113]; cell adhesion [GO:0007155]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of immunoglobulin secretion [GO:0051025]; regulation of B cell proliferation [GO:0030888]; regulation of endocytosis [GO:0030100]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell activation [GO:0042113]; cell adhesion [GO:0007155]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of immunoglobulin secretion [GO:0051025]; regulation of B cell proliferation [GO:0030888]; regulation of endocytosis [GO:0030100]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; CD4 receptor binding [GO:0042609]; IgM binding [GO:0001791]; protein phosphatase binding [GO:0019903]; sialic acid binding [GO:0033691]; signaling receptor binding [GO:0005102]
d1jnlh2_d3cfkn1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1jnll1_d5whjl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1jnnh2_d1figh1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1jnnl1_d4at6d2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1jnnl2_d1mcna1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1jnpa__d1jsga___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pronucleus [GO:0045120]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]; cellular response to tumor necrosis factor [GO:0071356]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein homotrimerization [GO:0070207]; regulation of stem cell population maintenance [GO:2000036]; stem cell population maintenance [GO:0019827]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]; cellular response to tumor necrosis factor [GO:0071356]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein homotrimerization [GO:0070207]	cellular response to tumor necrosis factor [GO:0071356]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein homotrimerization [GO:0070207]; regulation of stem cell population maintenance [GO:2000036]; stem cell population maintenance [GO:0019827]	cellular response to tumor necrosis factor [GO:0071356]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein homotrimerization [GO:0070207]	cell cortex [GO:0005938]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pronucleus [GO:0045120]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]	identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]
d1jnta__d2jzva1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	plasma membrane [GO:0005886]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]		protein folding [GO:0006457]	cytoplasm [GO:0005737]	plasma membrane [GO:0005886]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1jnub__d4hoia1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	axolemma [GO:0030673]; axon [GO:0030424]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nuclear inner membrane [GO:0005637]; parallel fiber to Purkinje cell synapse [GO:0098688]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; potassium channel complex [GO:0034705]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; voltage-gated potassium channel complex [GO:0008076]; 14-3-3 protein binding [GO:0071889]; calmodulin binding [GO:0005516]; delayed rectifier potassium channel activity [GO:0005251]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; phosphatidylinositol bisphosphate binding [GO:1902936]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; voltage-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099508]; voltage-gated potassium channel activity [GO:0005249]; cellular response to calcium ion [GO:0071277]; ion transmembrane transport [GO:0034220]; phosphatidylinositol-mediated signaling [GO:0048015]; potassium ion transmembrane transport [GO:0071805]; regulation of cell population proliferation [GO:0042127]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; regulation of synaptic vesicle exocytosis [GO:2000300]; startle response [GO:0001964]	detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cellular response to calcium ion [GO:0071277]; ion transmembrane transport [GO:0034220]; phosphatidylinositol-mediated signaling [GO:0048015]; potassium ion transmembrane transport [GO:0071805]; regulation of cell population proliferation [GO:0042127]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; regulation of synaptic vesicle exocytosis [GO:2000300]; startle response [GO:0001964]		axolemma [GO:0030673]; axon [GO:0030424]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nuclear inner membrane [GO:0005637]; parallel fiber to Purkinje cell synapse [GO:0098688]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; potassium channel complex [GO:0034705]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; voltage-gated potassium channel complex [GO:0008076]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]	14-3-3 protein binding [GO:0071889]; calmodulin binding [GO:0005516]; delayed rectifier potassium channel activity [GO:0005251]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; phosphatidylinositol bisphosphate binding [GO:1902936]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; voltage-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099508]; voltage-gated potassium channel activity [GO:0005249]
d1jnuc__d4eq1b1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]; aryl hydrocarbon receptor binding [GO:0017162]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; nuclear receptor activity [GO:0004879]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; cell differentiation [GO:0030154]; embryonic placenta development [GO:0001892]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; xenobiotic metabolic process [GO:0006805]	detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cell differentiation [GO:0030154]; embryonic placenta development [GO:0001892]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]	aryl hydrocarbon receptor binding [GO:0017162]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; nuclear receptor activity [GO:0004879]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]
d1jnyb1_d1zm2c1__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]			cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d1jnyb2_d1d2eb2__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]		mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1jnyb2_d4rd1a3__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1jnza3_d2wp9a2__1			Euryarchaeota	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]		aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d1jnzc1_d2wdqa3__1			Euryarchaeota	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]		aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d1joea__d1hr7d1__1		Fungi	Proteobacteria	Ascomycota	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]; quorum sensing [GO:0009372]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	quorum sensing [GO:0009372]	protein processing involved in protein targeting to mitochondrion [GO:0006627]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1jojb__d3gala___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1jojc__d3ilnb___1	Viridiplantae		Streptophyta	Bacteroidetes	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1jojd__d3ap9a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d1jola__d2w9sa___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d1joqa__d2f0wa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1jou.2_d1p04a___1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	serine-type endopeptidase activity [GO:0004252]
d1jou.2_d2f9pd___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1jova__d3buia2__1		Metazoa	Proteobacteria	Arthropoda	carbohydrate binding [GO:0030246]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; isomerase activity [GO:0016853]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1jowa2_d1oiyd2__1		Metazoa		Chordata	cell cycle [GO:0007049]; cell division [GO:0051301]; modulation by virus of host cell cycle [GO:0060153]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell cycle [GO:0007049]; cell division [GO:0051301]; modulation by virus of host cell cycle [GO:0060153]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]		Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]		ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1joya__d4jasa1__1			Proteobacteria	Thermotogae	cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; regulation of response to osmotic stress [GO:0047484]; signal transduction by protein phosphorylation [GO:0023014]	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; protein autophosphorylation [GO:0046777]	phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; regulation of response to osmotic stress [GO:0047484]; signal transduction by protein phosphorylation [GO:0023014]	protein autophosphorylation [GO:0046777]	cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]	integral component of plasma membrane [GO:0005887]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d1joza__d2cwia___1		Metazoa		Chordata		lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]; cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]		cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]				lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]
d1jp5a1_d3wkml2__1				Aquificae		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]				integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1jp5a1_d4y7ma___1				Proteobacteria								
d1jp5a2_d3qh3a1__1												
d1jp5b2_d1i8lb1__1		Metazoa		Chordata		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]		
d1jp5b2_d5xkub2__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d1jp6a__d2ig3b___1	Metazoa		Chordata	Proteobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d1jp8a__d1ktpa___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1jp9a__d1ha7e___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1jpba__d1hgcc___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1jpba__d2wtga___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1jpca__d1bwuq___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]			extracellular region [GO:0005576]		mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]
d1jpfa1_d3p2ta2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of T cell receptor signaling pathway [GO:0050860]; positive regulation of regulatory T cell differentiation [GO:0045591]; signal transduction [GO:0007165]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of T cell receptor signaling pathway [GO:0050860]; positive regulation of regulatory T cell differentiation [GO:0045591]; signal transduction [GO:0007165]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; signaling receptor activity [GO:0038023]
d1jpfb__d2aj3e2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1jpfb__d2v9ta___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]
d1jpia__d2ejaa___1	Metazoa		Chordata	Aquificae	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uroporphyrinogen decarboxylase activity [GO:0004853]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]; uroporphyrinogen decarboxylase activity [GO:0004853]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]	uroporphyrinogen decarboxylase activity [GO:0004853]	uroporphyrinogen decarboxylase activity [GO:0004853]
d1jpja2_d1m34o___1			Deinococcus-Thermus	Proteobacteria	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	nitrogen fixation [GO:0009399]	signal recognition particle [GO:0048500]	molybdenum-iron nitrogenase complex [GO:0016612]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1jpma2_d4k2sc1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d1jpna1_d1rj9b1__1			Deinococcus-Thermus	Deinococcus-Thermus	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]	signal recognition particle [GO:0048500]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1jpna2_d4ixna1__1			Deinococcus-Thermus	Proteobacteria	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; cellular response to DNA damage stimulus [GO:0006974]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cellular response to DNA damage stimulus [GO:0006974]	signal recognition particle [GO:0048500]	cytosol [GO:0005829]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]
d1jpoa__d2fbdb___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	lysozyme activity [GO:0003796]; metabolic process [GO:0008152]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	metabolic process [GO:0008152]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1jpra__d4ii4b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	phenylacetate catabolic process [GO:0010124]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	
d1jprb__d2z6ml___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1jpsh1_d2rcjq1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]		activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]		cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]	
d1jpsl2_d1hi6a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1jpth1_d3dggc2__1												
d1jptl2_d1jnnh1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1jpzb__d2ygxc___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]		aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1jq3a__d5lqka___1		Metazoa	Thermotogae	Chordata	cytosol [GO:0005829]; agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; sym-norspermidine synthase activity [GO:0050314]; thermospermine synthase activity [GO:0010487]; spermidine biosynthetic process [GO:0008295]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	spermidine biosynthetic process [GO:0008295]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytosol [GO:0005829]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; sym-norspermidine synthase activity [GO:0050314]; thermospermine synthase activity [GO:0010487]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d1jq3c__d2o06b___1		Metazoa	Thermotogae	Chordata	cytosol [GO:0005829]; agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; sym-norspermidine synthase activity [GO:0050314]; thermospermine synthase activity [GO:0010487]; spermidine biosynthetic process [GO:0008295]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; spermidine synthase activity [GO:0004766]; cellular response to leukemia inhibitory factor [GO:1990830]; polyamine biosynthetic process [GO:0006596]; polyamine metabolic process [GO:0006595]; spermidine biosynthetic process [GO:0008295]	spermidine biosynthetic process [GO:0008295]	cellular response to leukemia inhibitory factor [GO:1990830]; polyamine biosynthetic process [GO:0006596]; polyamine metabolic process [GO:0006595]; spermidine biosynthetic process [GO:0008295]	cytosol [GO:0005829]	cytosol [GO:0005829]	agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; sym-norspermidine synthase activity [GO:0050314]; thermospermine synthase activity [GO:0010487]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; spermidine synthase activity [GO:0004766]
d1jq8a__d3p2pa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]; bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	extracellular region [GO:0005576]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]
d1jq9a__d1c74a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]
d1jqba2_d4yagb___1			Firmicutes	Proteobacteria	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]					isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1jqbc2_d1qv7a2__1		Metazoa	Firmicutes	Chordata	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1jqbd2_d2rh4a___1			Firmicutes	Actinobacteria	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]		antibiotic biosynthetic process [GO:0017000]			isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	oxidoreductase activity [GO:0016491]
d1jqca__d1pima___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1jqcb__d5ww3d___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1jqeb__d3p8zc___1	Metazoa		Chordata		centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; histamine N-methyltransferase activity [GO:0046539]; brain development [GO:0007420]; histamine catabolic process [GO:0001695]; histidine catabolic process [GO:0006548]; hyperosmotic response [GO:0006972]; methylation [GO:0032259]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to amine [GO:0014075]; response to cocaine [GO:0042220]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to interleukin-1 [GO:0070555]; response to tumor cell [GO:0002347]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	brain development [GO:0007420]; histamine catabolic process [GO:0001695]; histidine catabolic process [GO:0006548]; hyperosmotic response [GO:0006972]; methylation [GO:0032259]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to amine [GO:0014075]; response to cocaine [GO:0042220]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to interleukin-1 [GO:0070555]; response to tumor cell [GO:0002347]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	histamine N-methyltransferase activity [GO:0046539]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1jqfa__d1b3ea___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d1jqga2_d1scjb___1	Metazoa		Arthropoda	Firmicutes	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1jqia1_d1rx0d1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; protein homotetramerization [GO:0051289]; response to glucocorticoid [GO:0051384]; response to starvation [GO:0042594]	mitochondrial matrix [GO:0005759]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; branched-chain amino acid catabolic process [GO:0009083]; lipid metabolic process [GO:0006629]; valine catabolic process [GO:0006574]	butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; protein homotetramerization [GO:0051289]; response to glucocorticoid [GO:0051384]; response to starvation [GO:0042594]	branched-chain amino acid catabolic process [GO:0009083]; lipid metabolic process [GO:0006629]; valine catabolic process [GO:0006574]	mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]	acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d1jqja3_d2xura2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1jqjb2_d2pola3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1jqjb3_d5f7ie1__1			Proteobacteria		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]		3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	
d1jqud__d1t3pa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1jqyh__d1fnvb1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1jqyx__d3r2ta1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1jqyy__d1bosr___1			Proteobacteria		extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	killing of cells of other organism [GO:0031640]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1jqyy__d4o1nb1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; peptidase activity [GO:0008233]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	peptidase activity [GO:0008233]
d1jqza1_d3fj9a1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1jqza1_d4depd1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]
d1jr0f__d1ty0a1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	pathogenesis [GO:0009405]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]
d1jr2a__d1wcwa1__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; mitochondrion [GO:0005739]; cofactor binding [GO:0048037]; uroporphyrinogen-III synthase activity [GO:0004852]; cellular response to amine stimulus [GO:0071418]; cellular response to arsenic-containing substance [GO:0071243]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to antibiotic [GO:0046677]; response to platinum ion [GO:0070541]; uroporphyrinogen III biosynthetic process [GO:0006780]	uroporphyrinogen-III synthase activity [GO:0004852]; uroporphyrinogen III biosynthetic process [GO:0006780]	cellular response to amine stimulus [GO:0071418]; cellular response to arsenic-containing substance [GO:0071243]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to antibiotic [GO:0046677]; response to platinum ion [GO:0070541]; uroporphyrinogen III biosynthetic process [GO:0006780]	uroporphyrinogen III biosynthetic process [GO:0006780]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		cofactor binding [GO:0048037]; uroporphyrinogen-III synthase activity [GO:0004852]	uroporphyrinogen-III synthase activity [GO:0004852]
d1jr4a__d5wz1e___1	Metazoa		Chordata		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1jr9a1_d4gunm1__1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1jrab__d3mbgb___1	Fungi	Metazoa	Ascomycota	Chordata	fungal-type vacuole [GO:0000324]; fungal-type vacuole membrane [GO:0000329]; integral component of endoplasmic reticulum membrane [GO:0030176]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	oxidation-reduction process [GO:0055114]		fungal-type vacuole [GO:0000324]; fungal-type vacuole membrane [GO:0000329]; integral component of endoplasmic reticulum membrane [GO:0030176]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]
d1jrac__d2hj3b___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	fungal-type vacuole [GO:0000324]; fungal-type vacuole membrane [GO:0000329]; integral component of endoplasmic reticulum membrane [GO:0030176]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]; oxidation-reduction process [GO:0055114]	mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; identical protein binding [GO:0042802]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]	oxidation-reduction process [GO:0055114]		fungal-type vacuole [GO:0000324]; fungal-type vacuole membrane [GO:0000329]; integral component of endoplasmic reticulum membrane [GO:0030176]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; identical protein binding [GO:0042802]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]
d1jrad__d3mbgc___1	Fungi	Metazoa	Ascomycota	Chordata	fungal-type vacuole [GO:0000324]; fungal-type vacuole membrane [GO:0000329]; integral component of endoplasmic reticulum membrane [GO:0030176]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	oxidation-reduction process [GO:0055114]		fungal-type vacuole [GO:0000324]; fungal-type vacuole membrane [GO:0000329]; integral component of endoplasmic reticulum membrane [GO:0030176]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]
d1jrea__d2v2ia___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1jrea__d4rc5b___1			Proteobacteria	Cyanobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	aldehyde decarbonylase activity [GO:0071771]; aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]		cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	aldehyde decarbonylase activity [GO:0071771]; aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]
d1jreb__d1eumd___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1jreb__d4m32d___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1jrec__d2xjnf___1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytoplasm [GO:0005737]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d1jree__d3ge4k___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1jree__d4toai___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1jreg__d5ww9d___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1jrej__d2f7na___1			Proteobacteria	Deinococcus-Thermus	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1jrhh1_d5u72e1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1jrhl1_d1q0xl2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1jrhl1_d3k80a1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	kinetoplast [GO:0020023]; mitochondrial mRNA editing complex [GO:0031019]; nucleus [GO:0005634]; endonuclease activity [GO:0004519]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; RNA modification [GO:0009451]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	RNA modification [GO:0009451]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	kinetoplast [GO:0020023]; mitochondrial mRNA editing complex [GO:0031019]; nucleus [GO:0005634]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	endonuclease activity [GO:0004519]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]
d1jria1_d4xq3b___1			Euryarchaeota	Crenarchaeota	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	mRNA splicing, via spliceosome [GO:0000398]	mRNA splicing, via spliceosome [GO:0000398]	small nucleolar ribonucleoprotein complex [GO:0005732]	small nucleolar ribonucleoprotein complex [GO:0005732]		
d1jrii1_d1vu3p___1			Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]			
d1jrik__d4xq3e___1			Euryarchaeota	Crenarchaeota	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	mRNA splicing, via spliceosome [GO:0000398]	mRNA splicing, via spliceosome [GO:0000398]	small nucleolar ribonucleoprotein complex [GO:0005732]	small nucleolar ribonucleoprotein complex [GO:0005732]		
d1jrim1_d3swne___1		Fungi	Euryarchaeota	Ascomycota	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	Lsm2-8 complex [GO:0120115]; nucleolus [GO:0005730]; nucleus [GO:0005634]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; maturation of SSU-rRNA [GO:0030490]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; telomerase holoenzyme complex assembly [GO:1905323]; tRNA processing [GO:0008033]	mRNA splicing, via spliceosome [GO:0000398]	maturation of SSU-rRNA [GO:0030490]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; telomerase holoenzyme complex assembly [GO:1905323]; tRNA processing [GO:0008033]	small nucleolar ribonucleoprotein complex [GO:0005732]	Lsm2-8 complex [GO:0120115]; nucleolus [GO:0005730]; nucleus [GO:0005634]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]		poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]
d1jrka1_d4hvya___1		Metazoa	Crenarchaeota	Chordata	hydrolase activity [GO:0016787]	cytosol [GO:0005829]; 8-hydroxy-dADP phosphatase activity [GO:0044717]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]; dADP catabolic process [GO:0046057]; dGDP catabolic process [GO:0046067]; GDP catabolic process [GO:0046712]; nucleobase-containing small molecule catabolic process [GO:0034656]		dADP catabolic process [GO:0046057]; dGDP catabolic process [GO:0046067]; GDP catabolic process [GO:0046712]; nucleobase-containing small molecule catabolic process [GO:0034656]		cytosol [GO:0005829]	hydrolase activity [GO:0016787]	8-hydroxy-dADP phosphatase activity [GO:0044717]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]
d1jrka1_d5i8ub___1			Crenarchaeota	Actinobacteria	hydrolase activity [GO:0016787]	cytosol [GO:0005829]; hydrolase activity [GO:0016787]; nucleoside phosphate metabolic process [GO:0006753]; ribose phosphate metabolic process [GO:0019693]		nucleoside phosphate metabolic process [GO:0006753]; ribose phosphate metabolic process [GO:0019693]		cytosol [GO:0005829]	hydrolase activity [GO:0016787]	hydrolase activity [GO:0016787]
d1jrkb1_d3dkuf___1			Crenarchaeota	Proteobacteria	hydrolase activity [GO:0016787]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]					hydrolase activity [GO:0016787]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]
d1jrkc1_d2a8ta___1		Metazoa	Crenarchaeota	Chordata	hydrolase activity [GO:0016787]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cobalt ion binding [GO:0050897]; dITP diphosphatase activity [GO:0035870]; GTP binding [GO:0005525]; ITP binding [GO:1901641]; m7G(5')pppN diphosphatase activity [GO:0050072]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; mRNA binding [GO:0003729]; nucleotide phosphatase activity, acting on free nucleotides [GO:0098519]; protein homodimerization activity [GO:0042803]; snoRNA binding [GO:0030515]; XTP binding [GO:1901640]; adenosine to inosine editing [GO:0006382]; dITP catabolic process [GO:0035863]; IDP catabolic process [GO:0046709]; mRNA catabolic process [GO:0006402]; negative regulation of rRNA processing [GO:2000233]; positive regulation of cell cycle process [GO:0090068]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of double-strand break repair [GO:2000781]; snoRNA catabolic process [GO:0016077]; XDP catabolic process [GO:1901639]		adenosine to inosine editing [GO:0006382]; dITP catabolic process [GO:0035863]; IDP catabolic process [GO:0046709]; mRNA catabolic process [GO:0006402]; negative regulation of rRNA processing [GO:2000233]; positive regulation of cell cycle process [GO:0090068]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of double-strand break repair [GO:2000781]; snoRNA catabolic process [GO:0016077]; XDP catabolic process [GO:1901639]		cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	hydrolase activity [GO:0016787]	cobalt ion binding [GO:0050897]; dITP diphosphatase activity [GO:0035870]; GTP binding [GO:0005525]; ITP binding [GO:1901641]; m7G(5')pppN diphosphatase activity [GO:0050072]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; mRNA binding [GO:0003729]; nucleotide phosphatase activity, acting on free nucleotides [GO:0098519]; protein homodimerization activity [GO:0042803]; snoRNA binding [GO:0030515]; XTP binding [GO:1901640]
d1jrkd1_d3shdj___1			Crenarchaeota	Proteobacteria	hydrolase activity [GO:0016787]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]					hydrolase activity [GO:0016787]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]
d1jroa1_d3faha2__1			Proteobacteria	Proteobacteria	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1jroa2_d2mjda___1		Fungi	Proteobacteria	Ascomycota	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	mitochondrial matrix [GO:0005759]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; heme a biosynthetic process [GO:0006784]; iron-sulfur cluster assembly [GO:0016226]; ubiquinone biosynthetic process [GO:0006744]		heme a biosynthetic process [GO:0006784]; iron-sulfur cluster assembly [GO:0016226]; ubiquinone biosynthetic process [GO:0006744]		mitochondrial matrix [GO:0005759]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d1jroa3_d1zxic1__1			Proteobacteria	Proteobacteria	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1jrob1_d3ax9b6__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1jroc2_d1v97a2__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1jroc2_d2w3ra1__1			Proteobacteria	Proteobacteria	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1jroc3_d3eubt2__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1jroc4_d3b9jb2__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1jroe4_d3nvzb1__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1jroe4_d4zohb1__1			Proteobacteria	Crenarchaeota	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1jroh1_d3ns1c1__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1jrpa2_d3ae2b1__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]		mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]		mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1jrpb1_d3eubl1__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1jrpc2_d1frda___1			Proteobacteria	Cyanobacteria	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; heterocyst differentiation [GO:0043158]; nitrogen fixation [GO:0009399]		heterocyst differentiation [GO:0043158]; nitrogen fixation [GO:0009399]			molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1jrpc3_d1fo4a4__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1jrpe2_d2cjoa___1			Proteobacteria	Cyanobacteria	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1jrpe2_d4kx6n1__1			Proteobacteria	Proteobacteria	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane fumarate reductase complex [GO:0045284]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; fumarate metabolic process [GO:0006106]		anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; fumarate metabolic process [GO:0006106]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane fumarate reductase complex [GO:0045284]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1jrpe3_d1n5wf1__1			Proteobacteria	Proteobacteria	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1jrpg1_d3nrza2__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1jrpg2_d3lxfa___1			Proteobacteria	Proteobacteria	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1jrsa__d1a1r.2__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]
d1jrta__d2xc4a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1jrxb3_d1jrya3__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]	electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]	electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]
d1js1x2_d2fg7y1__1			Bacteroidetes	Bacteroidetes	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	arginine biosynthetic process [GO:0006526]	arginine biosynthetic process [GO:0006526]			amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]
d1js1y2_d4jhxb1__1			Bacteroidetes	Proteobacteria	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	arginine biosynthetic process [GO:0006526]	arginine biosynthetic process [GO:0006526]		cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1js4a1_d1xw2a1__1			Actinobacteria	Proteobacteria	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	endo-1,4-beta-xylanase activity [GO:0031176]
d1js4a1_d3qpfa___1			Actinobacteria	Firmicutes	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	catalytic activity [GO:0003824]	cellulose catabolic process [GO:0030245]				cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	catalytic activity [GO:0003824]
d1js4b1_d1lf6a1__1			Actinobacteria	Firmicutes	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; polysaccharide metabolic process [GO:0005976]	cellulose catabolic process [GO:0030245]	polysaccharide metabolic process [GO:0005976]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]
d1js9b__d1rmu3___1					host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1jscb2_d1ovmc2__1	Fungi		Ascomycota	Proteobacteria	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; auxin biosynthetic process [GO:0009851]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	auxin biosynthetic process [GO:0009851]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1jsda__d4bsca___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1jsfa__d1c10a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1jsha__d4n5zw1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1jsha__d5xl7a___1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d1jsia__d4lkia___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1jslb__d5ot0e___1			Proteobacteria	Euryarchaeota	asparaginase activity [GO:0004067]; asparagine metabolic process [GO:0006528]	asparaginase activity [GO:0004067]; cellular amino acid metabolic process [GO:0006520]	asparagine metabolic process [GO:0006528]	cellular amino acid metabolic process [GO:0006520]			asparaginase activity [GO:0004067]	asparaginase activity [GO:0004067]
d1jsna__d4jtva___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1jsrc__d1nnsb___1			Proteobacteria	Proteobacteria	asparaginase activity [GO:0004067]; asparagine metabolic process [GO:0006528]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]; asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]	asparagine metabolic process [GO:0006528]	asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	asparaginase activity [GO:0004067]	asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]
d1jssb__d3ie5a1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; cholesterol binding [GO:0015485]; cholesterol transfer activity [GO:0120020]; cholesterol esterification [GO:0034435]; cholesterol import [GO:0070508]; cholesterol transport involved in cholesterol storage [GO:0010879]; intracellular cholesterol transport [GO:0032367]; positive regulation of bile acid biosynthetic process [GO:0070859]; positive regulation of cholesterol esterification [GO:0010873]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	cholesterol esterification [GO:0034435]; cholesterol import [GO:0070508]; cholesterol transport involved in cholesterol storage [GO:0010879]; intracellular cholesterol transport [GO:0032367]; positive regulation of bile acid biosynthetic process [GO:0070859]; positive regulation of cholesterol esterification [GO:0010873]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]		cholesterol binding [GO:0015485]; cholesterol transfer activity [GO:0120020]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d1jstb2_d2wihd1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1jstd2_d1gh6b2__1	Metazoa		Chordata		Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	host cell nucleus [GO:0042025]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]
d1jswb__d1tjud___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; aspartate ammonia-lyase activity [GO:0008797]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; tricarboxylic acid cycle [GO:0006099]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; tricarboxylic acid cycle [GO:0006099]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	cytosol [GO:0005829]; membrane [GO:0016020]		aspartate ammonia-lyase activity [GO:0008797]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]
d1jt0a1_d1pb6a3__1			Firmicutes		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]		negative regulation of transcription, DNA-templated [GO:0045892]				DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	
d1jt0c1_d5f0ha1__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d1jt3b1_d4qalb1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1jt6a1_d2xpwa1__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d1jt6b2_d5gp9a2__1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]	negative regulation of transcription, DNA-templated [GO:0045892]				DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d1jt6d1_d1bjza1__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d1jt7a1_d2nvha___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d1jt7b1_d4cjmd___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; growth factor activity [GO:0008083]; type 1 fibroblast growth factor receptor binding [GO:0005105]; type 2 fibroblast growth factor receptor binding [GO:0005111]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte development [GO:0002063]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor signaling pathway [GO:0008543]; intramembranous ossification [GO:0001957]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte development [GO:0002063]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor signaling pathway [GO:0008543]; intramembranous ossification [GO:0001957]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	growth factor activity [GO:0008083]; type 1 fibroblast growth factor receptor binding [GO:0005105]; type 2 fibroblast growth factor receptor binding [GO:0005111]
d1jtaa__d1rwra___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	cell surface [GO:0009986]	pectin catabolic process [GO:0045490]		extracellular region [GO:0005576]	cell surface [GO:0009986]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	
d1jtaa__d2o17a___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	pectin catabolic process [GO:0045490]	pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]
d1jtcc1_d1iila___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1jtcc1_d9ilba___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d1jtgd__d3gmwb___1			Proteobacteria	Actinobacteria	beta-lactamase activity [GO:0008800]; beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]		beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]				beta-lactamase activity [GO:0008800]	
d1jtka__d3zpcb1__1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	cytidine deamination [GO:0009972]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]		cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d1jtkb__d3wusb___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]	cytidine deamination [GO:0009972]	base conversion or substitution editing [GO:0016553]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]	cytosol [GO:0005829]	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1jtnb__d4owca___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1jtpl__d3g3xa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1jtsb__d5ww4a___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1jtsc__d3ka9a___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1jtsd__d3rnga___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d1jtsg__d3pwqe1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cytosol [GO:0005829]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	
d1jtsh__d1zs3l___1			Proteobacteria		cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]		cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]		cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	
d1jtsh__d5d8pb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1jtsk__d4todq___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1jtsl__d3e1nd___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1jtsn__d1mtyc___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1jtsp__d4p18d___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1jtsp__d5d8pk___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1jtsx__d2jd8z___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d1jtta__d43c9f___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1jtta__d4lria2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1jtxa1_d1zk8b1__1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]	negative regulation of transcription, DNA-templated [GO:0045892]				DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d1jtxa2_d3whca2__1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; fatty acid metabolic process [GO:0006631]; lipid catabolic process [GO:0016042]	negative regulation of transcription, DNA-templated [GO:0045892]	fatty acid metabolic process [GO:0006631]; lipid catabolic process [GO:0016042]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d1jtzy__d4qpyb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of JUN kinase activity [GO:0007257]; animal organ morphogenesis [GO:0009887]; bone development [GO:0060348]; bone resorption [GO:0045453]; calcium ion homeostasis [GO:0055074]; calcium-mediated signaling [GO:0019722]; cellular response to leukemia inhibitory factor [GO:1990830]; cytokine-mediated signaling pathway [GO:0019221]; ERK1 and ERK2 cascade [GO:0070371]; immune response [GO:0006955]; lymph node development [GO:0048535]; mammary gland alveolus development [GO:0060749]; mammary gland epithelial cell proliferation [GO:0033598]; monocyte chemotaxis [GO:0002548]; ossification [GO:0001503]; osteoclast development [GO:0036035]; osteoclast differentiation [GO:0030316]; osteoclast proliferation [GO:0002158]; paracrine signaling [GO:0038001]; positive regulation of bone resorption [GO:0045780]; positive regulation of corticotropin-releasing hormone secretion [GO:0051466]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling [GO:0071848]; positive regulation of fever generation by positive regulation of prostaglandin secretion [GO:0071812]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoclast development [GO:2001206]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin binding [GO:1904616]; regulation of osteoclast differentiation [GO:0045670]; TNFSF11-mediated signaling pathway [GO:0071847]; tooth eruption [GO:0044691]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	collagen trimer [GO:0005581]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]	activation of JUN kinase activity [GO:0007257]; animal organ morphogenesis [GO:0009887]; bone development [GO:0060348]; bone resorption [GO:0045453]; calcium ion homeostasis [GO:0055074]; calcium-mediated signaling [GO:0019722]; cellular response to leukemia inhibitory factor [GO:1990830]; cytokine-mediated signaling pathway [GO:0019221]; ERK1 and ERK2 cascade [GO:0070371]; immune response [GO:0006955]; lymph node development [GO:0048535]; mammary gland alveolus development [GO:0060749]; mammary gland epithelial cell proliferation [GO:0033598]; monocyte chemotaxis [GO:0002548]; ossification [GO:0001503]; osteoclast development [GO:0036035]; osteoclast differentiation [GO:0030316]; osteoclast proliferation [GO:0002158]; paracrine signaling [GO:0038001]; positive regulation of bone resorption [GO:0045780]; positive regulation of corticotropin-releasing hormone secretion [GO:0051466]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling [GO:0071848]; positive regulation of fever generation by positive regulation of prostaglandin secretion [GO:0071812]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoclast development [GO:2001206]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin binding [GO:1904616]; regulation of osteoclast differentiation [GO:0045670]; TNFSF11-mediated signaling pathway [GO:0071847]; tooth eruption [GO:0044691]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	collagen trimer [GO:0005581]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	identical protein binding [GO:0042802]
d1jtzy__d5tswd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of JUN kinase activity [GO:0007257]; animal organ morphogenesis [GO:0009887]; bone development [GO:0060348]; bone resorption [GO:0045453]; calcium ion homeostasis [GO:0055074]; calcium-mediated signaling [GO:0019722]; cellular response to leukemia inhibitory factor [GO:1990830]; cytokine-mediated signaling pathway [GO:0019221]; ERK1 and ERK2 cascade [GO:0070371]; immune response [GO:0006955]; lymph node development [GO:0048535]; mammary gland alveolus development [GO:0060749]; mammary gland epithelial cell proliferation [GO:0033598]; monocyte chemotaxis [GO:0002548]; ossification [GO:0001503]; osteoclast development [GO:0036035]; osteoclast differentiation [GO:0030316]; osteoclast proliferation [GO:0002158]; paracrine signaling [GO:0038001]; positive regulation of bone resorption [GO:0045780]; positive regulation of corticotropin-releasing hormone secretion [GO:0051466]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling [GO:0071848]; positive regulation of fever generation by positive regulation of prostaglandin secretion [GO:0071812]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoclast development [GO:2001206]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin binding [GO:1904616]; regulation of osteoclast differentiation [GO:0045670]; TNFSF11-mediated signaling pathway [GO:0071847]; tooth eruption [GO:0044691]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of JUN kinase activity [GO:0007257]; animal organ morphogenesis [GO:0009887]; bone development [GO:0060348]; bone resorption [GO:0045453]; calcium ion homeostasis [GO:0055074]; calcium-mediated signaling [GO:0019722]; cellular response to leukemia inhibitory factor [GO:1990830]; cytokine-mediated signaling pathway [GO:0019221]; ERK1 and ERK2 cascade [GO:0070371]; immune response [GO:0006955]; lymph node development [GO:0048535]; mammary gland alveolus development [GO:0060749]; mammary gland epithelial cell proliferation [GO:0033598]; monocyte chemotaxis [GO:0002548]; ossification [GO:0001503]; osteoclast development [GO:0036035]; osteoclast differentiation [GO:0030316]; osteoclast proliferation [GO:0002158]; paracrine signaling [GO:0038001]; positive regulation of bone resorption [GO:0045780]; positive regulation of corticotropin-releasing hormone secretion [GO:0051466]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling [GO:0071848]; positive regulation of fever generation by positive regulation of prostaglandin secretion [GO:0071812]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoclast development [GO:2001206]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin binding [GO:1904616]; regulation of osteoclast differentiation [GO:0045670]; TNFSF11-mediated signaling pathway [GO:0071847]; tooth eruption [GO:0044691]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d1ju4a1_d1jync3__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cocaine catabolic process [GO:0050784]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]	beta-galactosidase complex [GO:0009341]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1ju5a__d3vs4b2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]
d1ju6c__d4h1ic___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1jufb__d4bswa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1juga__d1inua___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1juia__d2jd4a1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	basement membrane [GO:0005604]; cell-cell junction [GO:0005911]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; laminin complex [GO:0043256]; laminin-1 complex [GO:0005606]; laminin-3 complex [GO:0005608]; membrane [GO:0016020]; extracellular matrix structural constituent [GO:0005201]; glycosphingolipid binding [GO:0043208]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; blood vessel morphogenesis [GO:0048514]; branching involved in salivary gland morphogenesis [GO:0060445]; camera-type eye development [GO:0043010]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of epithelial cell apical/basal polarity [GO:0045198]; morphogenesis of an epithelial sheet [GO:0002011]; neuron projection development [GO:0031175]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; retina development in camera-type eye [GO:0060041]; retinal blood vessel morphogenesis [GO:0061304]; tissue development [GO:0009888]		animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; blood vessel morphogenesis [GO:0048514]; branching involved in salivary gland morphogenesis [GO:0060445]; camera-type eye development [GO:0043010]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of epithelial cell apical/basal polarity [GO:0045198]; morphogenesis of an epithelial sheet [GO:0002011]; neuron projection development [GO:0031175]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; retina development in camera-type eye [GO:0060041]; retinal blood vessel morphogenesis [GO:0061304]; tissue development [GO:0009888]		basement membrane [GO:0005604]; cell-cell junction [GO:0005911]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; laminin-1 complex [GO:0005606]; laminin-3 complex [GO:0005608]; laminin complex [GO:0043256]; membrane [GO:0016020]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	extracellular matrix structural constituent [GO:0005201]; glycosphingolipid binding [GO:0043208]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]
d1juib__d2gntb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1juib__d3wg1b1__1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]		apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d1juic__d4gala___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1jujb__d1tsda___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cytosol [GO:0005829]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]
d1juob__d1nx1a___1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]; action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; proteolysis [GO:0006508]	action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	proteolysis [GO:0006508]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d1juob__d3m0wi___1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]; action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d1jusa1_d5ioza1__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]	negative regulation of transcription, DNA-templated [GO:0045892]				DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d1jusb1_d3br3b1__1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1juva__d4elhf1__1				Firmicutes	dihydrofolate reductase activity [GO:0004146]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1jv0b__d3jxfa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	integral component of plasma membrane [GO:0005887]; intrinsic component of plasma membrane [GO:0031226]; perineuronal net [GO:0072534]; plasma membrane [GO:0005886]; synapse [GO:0045202]; integrin binding [GO:0005178]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axonogenesis [GO:0007409]; central nervous system development [GO:0007417]; cytokine-mediated signaling pathway [GO:0019221]; hematopoietic progenitor cell differentiation [GO:0002244]; learning or memory [GO:0007611]; negative regulation of neuron apoptotic process [GO:0043524]; oligodendrocyte differentiation [GO:0048709]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of oligodendrocyte differentiation [GO:0048714]; protein dephosphorylation [GO:0006470]; regulation of myelination [GO:0031641]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	axonogenesis [GO:0007409]; central nervous system development [GO:0007417]; cytokine-mediated signaling pathway [GO:0019221]; hematopoietic progenitor cell differentiation [GO:0002244]; learning or memory [GO:0007611]; negative regulation of neuron apoptotic process [GO:0043524]; oligodendrocyte differentiation [GO:0048709]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of oligodendrocyte differentiation [GO:0048714]; protein dephosphorylation [GO:0006470]; regulation of myelination [GO:0031641]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	integral component of plasma membrane [GO:0005887]; intrinsic component of plasma membrane [GO:0031226]; perineuronal net [GO:0072534]; plasma membrane [GO:0005886]; synapse [GO:0045202]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]	integrin binding [GO:0005178]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d1jv0b__d3rz5a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1jv2a4_d5hdbc___1	Metazoa	Metazoa	Chordata	Chordata	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; cell [GO:0005623]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin alphav-beta5 complex [GO:0034684]; integrin alphav-beta6 complex [GO:0034685]; integrin alphav-beta8 complex [GO:0034686]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; microvillus membrane [GO:0031528]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; specific granule membrane [GO:0035579]; coreceptor activity [GO:0015026]; extracellular matrix binding [GO:0050840]; extracellular matrix protein binding [GO:1990430]; fibronectin binding [GO:0001968]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; opsonin binding [GO:0001846]; protease binding [GO:0002020]; protein kinase C binding [GO:0005080]; transforming growth factor beta binding [GO:0050431]; virus receptor activity [GO:0001618]; voltage-gated calcium channel activity [GO:0005245]; angiogenesis [GO:0001525]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; endodermal cell differentiation [GO:0035987]; entry of symbiont into host cell by promotion of host phagocytosis [GO:0052066]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; negative chemotaxis [GO:0050919]; negative regulation of entry of bacterium into host cell [GO:2000536]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; neutrophil degranulation [GO:0043312]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of phagocytosis [GO:0050764]; regulation of transforming growth factor beta activation [GO:1901388]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor-beta secretion [GO:0038044]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral entry into host cell [GO:0046718]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	angiogenesis [GO:0001525]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; endodermal cell differentiation [GO:0035987]; entry of symbiont into host cell by promotion of host phagocytosis [GO:0052066]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; negative chemotaxis [GO:0050919]; negative regulation of entry of bacterium into host cell [GO:2000536]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; neutrophil degranulation [GO:0043312]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of phagocytosis [GO:0050764]; regulation of transforming growth factor beta activation [GO:1901388]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor-beta secretion [GO:0038044]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral entry into host cell [GO:0046718]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; cell [GO:0005623]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin alphav-beta5 complex [GO:0034684]; integrin alphav-beta6 complex [GO:0034685]; integrin alphav-beta8 complex [GO:0034686]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; microvillus membrane [GO:0031528]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; specific granule membrane [GO:0035579]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	coreceptor activity [GO:0015026]; extracellular matrix binding [GO:0050840]; extracellular matrix protein binding [GO:1990430]; fibronectin binding [GO:0001968]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; opsonin binding [GO:0001846]; protease binding [GO:0002020]; protein kinase C binding [GO:0005080]; transforming growth factor beta binding [GO:0050431]; virus receptor activity [GO:0001618]; voltage-gated calcium channel activity [GO:0005245]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1jv4a__d1x8ua___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1jv4a__d4orwa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d1jvfa__d3qwid___1		Fungi		Ascomycota		nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]						nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1jvfc__d5icsc1__1		Metazoa		Chordata		cytosol [GO:0005829]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]		estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]		cytosol [GO:0005829]		estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]
d1jvfd__d4b4vb2__1				Proteobacteria		methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; nucleotide binding [GO:0000166]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]		histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]				methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; nucleotide binding [GO:0000166]
d1jvka1_d1f3dl1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	metal ion binding [GO:0046872]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d1jvka2_d5ks9h1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1jvkb2_d5grul1__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1jvla__d1mzzc1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1jvlb__d2dy2a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1jvoa__d1etjc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1jvob__d1kbvd1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	cell outer membrane [GO:0009279]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1jvoc__d4bxvb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1jvod__d2xx1e2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1jvof__d1nica2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1jvog__d1ndrc2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1jvoh__d2bwda2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1jvoi__d1sjmb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1jvoi__d3u25a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1jvxa__d5jeia1__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1jw1a2_d1dtga___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	extracellular space [GO:0005615]; specific granule [GO:0042581]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d1jw1a2_d5cbsb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	extracellular space [GO:0005615]; specific granule [GO:0042581]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1jw6a__d3zpya___1	Viridiplantae		Streptophyta	Bacteroidetes	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	poly(beta-D-mannuronate) lyase activity [GO:0045135]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	poly(beta-D-mannuronate) lyase activity [GO:0045135]
d1jwda__d4hsza___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; calcium ion binding [GO:0005509]; protein N-terminus binding [GO:0047485]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]		epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium ion binding [GO:0005509]; protein N-terminus binding [GO:0047485]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d1jwda__d5hkwa2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; calcium ion binding [GO:0005509]; protein N-terminus binding [GO:0047485]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]		cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; protein N-terminus binding [GO:0047485]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]
d1jwfa__d5lp0c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]		cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]		cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]		ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	
d1jwga__d1sz9a1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA polymerase II complex binding [GO:0000993]; mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; termination of RNA polymerase II transcription [GO:0006369]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; termination of RNA polymerase II transcription, poly(A)-coupled [GO:0030846]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; termination of RNA polymerase II transcription [GO:0006369]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; termination of RNA polymerase II transcription, poly(A)-coupled [GO:0030846]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	mRNA binding [GO:0003729]; RNA polymerase II complex binding [GO:0000993]
d1jwib__d1ixxe___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]
d1jwmb2_d1d5xa2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d1jwna__d3eu1d___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1jwnb__d5nb4e___1	Metazoa		Mollusca	Cyanobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1jwnd__d4xdib___1	Metazoa	Viridiplantae	Mollusca	Chlorophyta	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; thioredoxin peroxidase activity [GO:0008379]
d1jwoa__d1lcka2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713]; ERBB2 signaling pathway [GO:0038128]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	ERBB2 signaling pathway [GO:0038128]; positive regulation of cell population proliferation [GO:0008284]; protein phosphorylation [GO:0006468]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]
d1jwqa__d1lcpa2__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	peptidoglycan catabolic process [GO:0009253]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]	aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]
d1jwqa__d1xova2__1			Firmicutes		metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan catabolic process [GO:0009253]	helicase activity [GO:0004386]; metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan catabolic process [GO:0009253]	peptidoglycan catabolic process [GO:0009253]	peptidoglycan catabolic process [GO:0009253]			metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]	helicase activity [GO:0004386]; metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]
d1jwsb2_d1duyd2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1jwub2_d4l3ci1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1jx9.1_d4e57a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; metal ion binding [GO:0046872]; antibiotic biosynthetic process [GO:0017000]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	antibiotic biosynthetic process [GO:0017000]	periplasmic space [GO:0042597]		metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; metal ion binding [GO:0046872]
d1jxab2_d1ofeb3__1			Proteobacteria	Cyanobacteria	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	3 iron, 4 sulfur cluster binding [GO:0051538]; glutamate synthase (ferredoxin) activity [GO:0016041]; metal ion binding [GO:0046872]; glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054]	cytosol [GO:0005829]		carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	3 iron, 4 sulfur cluster binding [GO:0051538]; glutamate synthase (ferredoxin) activity [GO:0016041]; metal ion binding [GO:0046872]
d1jxba__d3irxa2__1			Proteobacteria		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1jxda__d2ccwa___1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1jxda__d2p80a2__1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1jxfa__d1cc3b___1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1jxga__d1nzra___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane [GO:0009535]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1jxgb__d2xyba1__1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]			chloroplast thylakoid membrane [GO:0009535]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1jxja2_d4w85b___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]
d1jxka2_d1w91g2__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d1jxla1_d1k1sa1__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d1jxna__d3l2ym___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1jxnc__d1uzzd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1jxp.2_d5esba1__1					extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; transformation of host cell by virus [GO:0019087]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	transformation of host cell by virus [GO:0019087]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d1jxra__d4zlsb___1						host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1jxra__d5p85a___1		Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]						aspartic-type endopeptidase activity [GO:0004190]
d1jxsa__d5hs7b1__1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; magnesium ion binding [GO:0000287]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; negative regulation of autophagy [GO:0010507]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter [GO:0035947]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; response to starvation [GO:0042594]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]	canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; negative regulation of autophagy [GO:0010507]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter [GO:0035947]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to starvation [GO:0042594]	negative regulation of transcription, DNA-templated [GO:0045892]	cell [GO:0005623]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protein-DNA complex [GO:0032993]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; magnesium ion binding [GO:0000287]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1jxva__d3evwa1__1	Metazoa		Chordata		cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]; cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]		ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1jxvb__d1vyac___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]; cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]	nucleus [GO:0005634]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]
d1jxvd__d3q8ud___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]; cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1jxvf__d3q8vg___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]; cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1jy7b__d3dr9a___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d1jy7p__d2vmll___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1jyca__d1lof.1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]
d1jyfa__d3edcc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]	cytosol [GO:0005829]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]
d1jyfa__d3ma0a1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	outer membrane-bounded periplasmic space [GO:0030288]; monosaccharide binding [GO:0048029]; D-xylose metabolic process [GO:0042732]; D-xylose transmembrane transport [GO:0015753]	negative regulation of transcription, DNA-templated [GO:0045892]	D-xylose metabolic process [GO:0042732]; D-xylose transmembrane transport [GO:0015753]	cytosol [GO:0005829]	outer membrane-bounded periplasmic space [GO:0030288]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]	monosaccharide binding [GO:0048029]
d1jyha__d1r8ea2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity [GO:0008657]; enzyme binding [GO:0019899]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation of DNA-dependent DNA replication [GO:2000104]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	cellular response to DNA damage stimulus [GO:0006974]; negative regulation of DNA-dependent DNA replication [GO:2000104]	regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]		DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity [GO:0008657]; enzyme binding [GO:0019899]	DNA binding [GO:0003677]
d1jyia__d1kita2__1	Viridiplantae		Streptophyta	Proteobacteria	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]; ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]		ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]
d1jylb1_d2v0ia1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d1jylc1_d5ftsd___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]			metal ion binding [GO:0046872]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1jyld1_d1fxob___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]			metal ion binding [GO:0046872]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1jyna3_d1uxzb___1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1jyna5_d1qoxc___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1jynb1_d3t2oa4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jynb5_d1mw2a2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amylosucrase activity [GO:0047669]
d1jync2_d3vd4c2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jync4_d1ulva4__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]; polysaccharide metabolic process [GO:0005976]	lactose catabolic process [GO:0005990]	polysaccharide metabolic process [GO:0005976]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]
d1jync5_d4pmyb___1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]
d1jynd2_d3dyoc2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jynd5_d3pbgb___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	6-phospho-beta-galactosidase activity [GO:0033920]; lactose catabolic process via tagatose-6-phosphate [GO:0019512]	lactose catabolic process [GO:0005990]	lactose catabolic process via tagatose-6-phosphate [GO:0019512]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	6-phospho-beta-galactosidase activity [GO:0033920]
d1jyva2_d3vd5c2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jyva5_d2x2ya1__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]
d1jyvb5_d4duva3__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jyvc1_d1jz4b2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jyvc3_d2vzva1__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1jyvc4_d2xhna1__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]
d1jyvd3_d1uz0a___1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1jywa1_d2vo5a3__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-mannosidase activity [GO:0004567]
d1jywa1_d3i3ea4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jywa4_d1mmxa1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1jywb1_d3e1f44__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jywb5_d1jyyd5__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d1jywc2_d3dypc2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jywc5_d1e0xa___1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d1jywc5_d1vaha2__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	lactose catabolic process [GO:0005990]	carbohydrate catabolic process [GO:0016052]	beta-galactosidase complex [GO:0009341]	extracellular space [GO:0005615]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1jywd3_d5jxga2__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	lactose catabolic process [GO:0005990]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	beta-galactosidase complex [GO:0009341]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d1jywd4_d3buqa2__1		Metazoa	Proteobacteria	Arthropoda	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1jyxa1_d3t0bd4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jyxa2_d3i3eb2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jyxb1_d5c71a2__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1jyxb2_d1bglh1__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d1jyxb2_d3muy32__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jyxb3_d5ihra4__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]; carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]
d1jyxb4_d3l4xa1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	lactose catabolic process [GO:0005990]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	beta-galactosidase complex [GO:0009341]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]
d1jyxb5_d5effb___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]
d1jyxc3_d2b9ve1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d1jyxc5_d1avab2__1		Viridiplantae	Proteobacteria	Streptophyta	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]
d1jyxc5_d1expa___1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]
d1jyxd3_d4z2aa2__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	lactose catabolic process [GO:0005990]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	beta-galactosidase complex [GO:0009341]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d1jyya1_d4duxb4__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jyya5_d4bs0a___1		Fungi		Ascomycota		endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]
d1jyya5_d4n42a___1		Viridiplantae		Streptophyta		alpha-amylase inhibitor activity [GO:0015066]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]				alpha-amylase inhibitor activity [GO:0015066]; hydrolase activity, acting on glycosyl bonds [GO:0016798]
d1jyyb1_d3muy44__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jyyc5_d1v08b___1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]		carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]		chloroplast [GO:0009507]		beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]
d1jyye3_d2bera2__1				Actinobacteria		extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]		metabolic process [GO:0008152]		extracellular region [GO:0005576]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1jyyf1_d3sepb4__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jyyf5_d1byda___1		Viridiplantae		Streptophyta		amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]				amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d1jyyh1_d2vr4a3__1				Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]
d1jyyh2_d3vdbc2__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jyzj5_d3gxfd2__1		Metazoa		Chordata		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1jyzk2_d3i3dc2__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jyzk2_d3t2qc2__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jyzm1_d2vl4a3__1				Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]
d1jyzm5_d2whja1__1				Firmicutes		mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				mannan endo-1,4-beta-mannosidase activity [GO:0016985]
d1jyzn1_d3hn3b2__1		Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]		carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]		beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]
d1jyzn2_d3t09c2__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jyzp5_d1e0va___1				Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d1jyzp5_d1xsib4__1				Proteobacteria		alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1jz0a5_d1eswa___1				Deinococcus-Thermus		cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]				cytoplasm [GO:0005737]		4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]
d1jz0b2_d1jz6b1__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz0c2_d1ghoo1__1												
d1jz0d3_d2vmha___1				Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1jz0e3_d2e33a___1		Metazoa		Chordata		extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]				extracellular region [GO:0005576]		endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1jz0f2_d3dyob2__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz0f5_d1itca2__1				Firmicutes		amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]				amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1jz0g2_d2vzob2__1				Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1jz0g5_d1kqza___1		Viridiplantae		Streptophyta		vacuole [GO:0005773]; chitinase activity [GO:0004568]; lysozyme activity [GO:0003796]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		vacuole [GO:0005773]		chitinase activity [GO:0004568]; lysozyme activity [GO:0003796]
d1jz0h3_d1uxxx___1				Firmicutes		carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]				carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]
d1jz0h5_d4ptwb___1				Firmicutes		beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]				beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1jz1i3_d1nx9a1__1				Proteobacteria		alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]						alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d1jz1i5_d3wq8l___1				Euryarchaeota		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1jz1j2_d3sepd2__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz1j5_d1e5na___1				Proteobacteria		cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]				cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]
d1jz1j5_d3edja2__1				Bacteroidetes		cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d1jz1l2_d1jyzl1__1												
d1jz1l2_d2vzua5__1				Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1jz1l3_d5ifta4__1		Fungi		Ascomycota		extracellular region [GO:0005576]; beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]; carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]		carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]
d1jz1m1_d3t2qa4__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz1m2_d1bglg1__1												
d1jz1n1_d4jklb2__1				Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1jz1n5_d5i78a1__1		Fungi		Ascomycota		extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		cellulase activity [GO:0008810]
d1jz1o1_d2vzva2__1				Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1jz1p1_d3t09c4__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz2a1_d2x05b5__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1jz2a2_d4jhzb2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	lactose catabolic process [GO:0005990]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	beta-galactosidase complex [GO:0009341]	cytosol [GO:0005829]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d1jz2c5_d1gzjb___1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulase activity [GO:0008810]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cellulase activity [GO:0008810]
d1jz2d1_d3k46a2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	lactose catabolic process [GO:0005990]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	beta-galactosidase complex [GO:0009341]	cytosol [GO:0005829]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d1jz2d5_d3s5zb1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	lactose catabolic process [GO:0005990]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	beta-galactosidase complex [GO:0009341]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d1jz3b1_d4duxd4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz3c5_d3gxib2__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	lactose catabolic process [GO:0005990]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1jz3d1_d2vjxb3__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-mannosidase activity [GO:0004567]
d1jz3d5_d3bmwa4__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1jz4a2_d1jz5b1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz4a4_d5m16a1__1			Proteobacteria	Thermotogae	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	alpha-galactosidase activity [GO:0004557]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; carbohydrate metabolic process [GO:0005975]; glycoside catabolic process [GO:0016139]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoside catabolic process [GO:0016139]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-galactosidase activity [GO:0004557]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]
d1jz4a5_d2nt1a2__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	lactose catabolic process [GO:0005990]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1jz4b3_d3k77b___1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	lactose catabolic process [GO:0005990]	base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	beta-galactosidase complex [GO:0009341]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]
d1jz4d2_d3czja2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz4d4_d1mmub1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1jz5a2_d5c70b2__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1jz5a3_d4rydb2__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	lactose catabolic process [GO:0005990]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	beta-galactosidase complex [GO:0009341]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d1jz5a4_d3njva1__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]
d1jz5c1_d1jz6d2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz5c2_d1jz2d1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz5d1_d4duxa4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz5d3_d4xupe___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d1jz5d4_d3blba2__1		Metazoa	Proteobacteria	Arthropoda	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1jz6a1_d3sepa4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz6a2_d3t09a2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz6b4_d1mmxb1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1jz6b5_d5jbkb___1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1jz6c1_d2vzoa2__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1jz6c2_d4duvd2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz6d1_d3t0ab4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz6d3_d2vz1a2__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]
d1jz6d5_d1c7sa3__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	periplasmic space [GO:0042597]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]
d1jz7b3_d1tvga___1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; intraciliary transport particle B [GO:0030992]; metal ion binding [GO:0046872]; cell differentiation [GO:0030154]; heart development [GO:0007507]; intraciliary transport involved in cilium assembly [GO:0035735]; kidney development [GO:0001822]; left/right axis specification [GO:0070986]; lung development [GO:0030324]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283]	lactose catabolic process [GO:0005990]	cell differentiation [GO:0030154]; heart development [GO:0007507]; intraciliary transport involved in cilium assembly [GO:0035735]; kidney development [GO:0001822]; left/right axis specification [GO:0070986]; lung development [GO:0030324]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283]	beta-galactosidase complex [GO:0009341]	centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; intraciliary transport particle B [GO:0030992]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]
d1jz7b5_d1gjwa2__1			Proteobacteria	Thermotogae	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	transferase activity [GO:0016740]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	transferase activity [GO:0016740]
d1jz7c5_d1v0la___1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d1jz7d5_d1aq0a___1		Viridiplantae	Proteobacteria	Streptophyta	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	licheninase activity [GO:0042972]
d1jz8a1_d3t0da4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz8b1_d1f4hc2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz8c1_d3vd3d4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz8c5_d1jyxa5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1jz8d4_d3l4wa1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	lactose catabolic process [GO:0005990]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	beta-galactosidase complex [GO:0009341]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]
d1jzdb1_d4k1fd___1			Proteobacteria		cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cell [GO:0005623]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]
d1jzea__d1xb6b___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1jzea__d2eiko1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	oxidation-reduction process [GO:0055114]	ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1jzga__d5b7ma1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d1jzia__d5ue6c2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1jzib__d1ndsa1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1jzkd__d2uunp___1	Metazoa		Mollusca		cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1jzma__d3v2za___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1jzna__d3ff8d___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]		adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1jznb__d4ak8b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]		antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	extracellular region [GO:0005576]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1jznc__d4n34c___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]		antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	extracellular region [GO:0005576]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1jznd__d3p5da___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]		antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	extracellular region [GO:0005576]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1jzqa1_d4mw5a2__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; isoleucyl-tRNA aminoacylation [GO:0006428]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	isoleucyl-tRNA aminoacylation [GO:0006428]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]
d1jzra2_d2xbqa___1	Fungi	Metazoa	Ascomycota	Platyhelminthes	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell [GO:0005623]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]
d1jzrb2_d1gwca2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	glutathione transferase activity [GO:0004364]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasm [GO:0005737]		glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	glutathione transferase activity [GO:0004364]
d1jzrc2_d4ri6a1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cytoplasm [GO:0005737]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1jzrd1_d5dcga2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1jzsa1_d4mw4a2__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; isoleucyl-tRNA aminoacylation [GO:0006428]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	isoleucyl-tRNA aminoacylation [GO:0006428]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]
d1jzua__d1np1b___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular region [GO:0005576]; arachidonic acid binding [GO:0050544]; enterobactin binding [GO:1903981]; oleic acid binding [GO:0070538]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]	vasodilation [GO:0042311]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	arachidonic acid binding [GO:0050544]; enterobactin binding [GO:1903981]; oleic acid binding [GO:0070538]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]
d1k03a__d1ps9a1__1	Fungi		Ascomycota	Proteobacteria	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]	2,4-dienoyl-CoA reductase (NADPH) activity [GO:0008670]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway [GO:0033543]		fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway [GO:0033543]			FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]	2,4-dienoyl-CoA reductase (NADPH) activity [GO:0008670]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1k07a__d5k0wb___1			Proteobacteria	Bacteroidetes	beta-lactamase activity [GO:0008800]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					beta-lactamase activity [GO:0008800]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1k0bd1_d3zmkb2__1	Fungi	Metazoa	Ascomycota	Arthropoda	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	transferase activity [GO:0016740]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasm [GO:0005737]		glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	transferase activity [GO:0016740]
d1k0ca2_d1qq2b___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]; heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d1k0cb2_d5ecnc1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1k0cc2_d1tu7a2__1	Fungi	Metazoa	Ascomycota	Nematoda (roundworms)	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	glutathione transferase activity [GO:0004364]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasm [GO:0005737]		glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	glutathione transferase activity [GO:0004364]
d1k0cd2_d2i81a___1	Fungi		Ascomycota	Apicomplexa	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	peroxiredoxin activity [GO:0051920]
d1k0db2_d2on7c1__1	Fungi		Ascomycota		cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasm [GO:0005737]		glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	
d1k0dc2_d10gsb2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1k0dd2_d1sl2b___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1k0ma2_d4kb3f___1	Metazoa		Chordata		blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cell [GO:0005623]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1k0mb2_d2yp6d___1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cell [GO:0005623]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]
d1k0na2_d5a5kf1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d1k0nb2_d3i6af1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1k0oa2_d1vf3a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	glutathione transferase activity [GO:0004364]
d1k0oa2_d5djla1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1k0ob2_d1gtuc2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d1k0ob2_d4kb3e___1	Metazoa		Chordata		blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cell [GO:0005623]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1k0ta__d1gtec5__1		Metazoa	Cyanobacteria	Chordata	photosystem I [GO:0009522]; thylakoid membrane [GO:0042651]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem I [GO:0009773]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	photosynthetic electron transport in photosystem I [GO:0009773]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	photosystem I [GO:0009522]; thylakoid membrane [GO:0042651]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d1k0ua1_d1psda1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	L-serine biosynthetic process [GO:0006564]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	cytosol [GO:0005829]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]
d1k0ua1_d4jnkd1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1k0ub1_d1hkua1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; neuron projection [GO:0043005]; nucleus [GO:0005634]; presynapse [GO:0098793]; transcriptional repressor complex [GO:0017053]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; transferase activity, transferring acyl groups [GO:0016746]; membrane fusion [GO:0061025]; negative regulation of transcription, DNA-templated [GO:0045892]; presynapse to nucleus signaling pathway [GO:0099526]; white fat cell differentiation [GO:0050872]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	membrane fusion [GO:0061025]; negative regulation of transcription, DNA-templated [GO:0045892]; presynapse to nucleus signaling pathway [GO:0099526]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; neuron projection [GO:0043005]; nucleus [GO:0005634]; presynapse [GO:0098793]; transcriptional repressor complex [GO:0017053]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; transferase activity, transferring acyl groups [GO:0016746]
d1k0ub1_d2ae2a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	tropinone reductase activity [GO:0050358]; tropane alkaloid biosynthetic process [GO:0009710]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	tropane alkaloid biosynthetic process [GO:0009710]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]		adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	tropinone reductase activity [GO:0050358]
d1k0uc1_d3k92a2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]		adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	glutamate dehydrogenase (NAD+) activity [GO:0004352]
d1k0ud1_d1bxzd2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]		adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]
d1k0uh1_d1h5qf___1	Metazoa	Fungi	Chordata	Basidiomycota	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]		adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]
d1k0wb__d2v9gb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]
d1k0wd__d1e46p___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]	aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]
d1k0wf__d1e4cp___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]; L-lyxose metabolic process [GO:0019324]; pentose catabolic process [GO:0019323]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; L-ribulose-phosphate 4-epimerase activity [GO:0008742]; zinc ion binding [GO:0008270]	aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]
d1k19a__d1n8va___1	Metazoa	Metazoa	Arthropoda	Arthropoda								
d1k1eh__d1rdfc___1			Proteobacteria	Firmicutes	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	lipopolysaccharide biosynthetic process [GO:0009103]	organic phosphonate catabolic process [GO:0019700]			3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]
d1k1el__d4jdpb1__1			Proteobacteria	Euryarchaeota	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	metal ion binding [GO:0046872]	lipopolysaccharide biosynthetic process [GO:0009103]				3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1k1kb__d2uulw___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1k1oa__d2aeih___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	digestion [GO:0007586]; proteolysis [GO:0006508]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d1k1qa1_d1t3nb1__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	cytoplasmic ribonucleoprotein granule [GO:0036464]; intracellular [GO:0005622]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]	cytoplasmic ribonucleoprotein granule [GO:0036464]; intracellular [GO:0005622]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d1k1qa1_d2jeja1__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d1k1qb1_d2w8la2__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d1k1sa1_d2jefa1__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d1k1ta__d2aofb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1k1tb__d2qhza___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1k1tb__d5p8ka___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1k1ub__d4u8wa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1k1ya3_d3cl7b___1			Euryarchaeota	Proteobacteria	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]
d1k21.1_d2sgee___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	serine-type endopeptidase inhibitor activity [GO:0004867]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1k22.1_d1qbna___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1k28a3_d1qt8a___1					virion [GO:0019012]; virus tail [GO:0098015]; virus tail, baseplate [GO:0098025]; viral tail assembly [GO:0098003]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	viral tail assembly [GO:0098003]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	virion [GO:0019012]; virus tail [GO:0098015]; virus tail, baseplate [GO:0098025]	host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]
d1k28a3_d1qtka___1		Metazoa		Chordata	virion [GO:0019012]; virus tail [GO:0098015]; virus tail, baseplate [GO:0098025]; viral tail assembly [GO:0098003]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	viral tail assembly [GO:0098003]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	virion [GO:0019012]; virus tail [GO:0098015]; virus tail, baseplate [GO:0098025]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1k2da1_d1ibgh2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]		adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]	
d1k2da2_d5ks9d1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]	
d1k2ob__d4umzb___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1k2vn__d4wzab___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	nitrogen fixation [GO:0009399]	outer membrane-bounded periplasmic space [GO:0030288]	molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1k2wa__d1sbya___1		Metazoa	Proteobacteria	Arthropoda	galactitol 2-dehydrogenase activity [GO:0047713]; L-iditol 2-dehydrogenase activity [GO:0003939]; carbohydrate metabolic process [GO:0005975]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]; alcohol metabolic process [GO:0006066]	carbohydrate metabolic process [GO:0005975]	alcohol metabolic process [GO:0006066]			galactitol 2-dehydrogenase activity [GO:0047713]; L-iditol 2-dehydrogenase activity [GO:0003939]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]
d1k2wb__d3ai3a___1			Proteobacteria	Proteobacteria	galactitol 2-dehydrogenase activity [GO:0047713]; L-iditol 2-dehydrogenase activity [GO:0003939]; carbohydrate metabolic process [GO:0005975]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	carbohydrate metabolic process [GO:0005975]				galactitol 2-dehydrogenase activity [GO:0047713]; L-iditol 2-dehydrogenase activity [GO:0003939]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1k2yx2_d1lxta3__1		Metazoa	Proteobacteria	Chordata	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	glucose metabolic process [GO:0006006]		sarcoplasmic reticulum [GO:0016529]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1k2yx4_d3pmgb4__1		Metazoa	Proteobacteria	Chordata	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	glucose metabolic process [GO:0006006]		sarcoplasmic reticulum [GO:0016529]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1k31a__d2x51b___1		Metazoa		Arthropoda		cell [GO:0005623]; cell cortex [GO:0005938]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; myosin V complex [GO:0031475]; myosin VI complex [GO:0031476]; nucleoplasm [GO:0005654]; rhabdomere [GO:0016028]; spindle [GO:0005819]; calcium ion binding [GO:0005509]; myosin heavy chain binding [GO:0032036]; myosin V binding [GO:0031489]; myosin VI head/neck binding [GO:0070855]; actin filament-based movement [GO:0030048]; adaptation of rhodopsin mediated signaling [GO:0016062]; calcium-mediated signaling [GO:0019722]; cellular response to ethanol [GO:0071361]; centriole replication [GO:0007099]; deactivation of rhodopsin mediated signaling [GO:0016059]; kinetochore organization [GO:0051383]; metarhodopsin inactivation [GO:0016060]; muscle cell cellular homeostasis [GO:0046716]; photoreceptor cell axon guidance [GO:0072499]; positive regulation of cation channel activity [GO:2001259]; protein phosphorylation [GO:0006468]; regulation of light-activated channel activity [GO:0016061]; rhabdomere development [GO:0042052]; rhodopsin mediated signaling pathway [GO:0016056]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]		actin filament-based movement [GO:0030048]; adaptation of rhodopsin mediated signaling [GO:0016062]; calcium-mediated signaling [GO:0019722]; cellular response to ethanol [GO:0071361]; centriole replication [GO:0007099]; deactivation of rhodopsin mediated signaling [GO:0016059]; kinetochore organization [GO:0051383]; metarhodopsin inactivation [GO:0016060]; muscle cell cellular homeostasis [GO:0046716]; photoreceptor cell axon guidance [GO:0072499]; positive regulation of cation channel activity [GO:2001259]; protein phosphorylation [GO:0006468]; regulation of light-activated channel activity [GO:0016061]; rhabdomere development [GO:0042052]; rhodopsin mediated signaling pathway [GO:0016056]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]		cell [GO:0005623]; cell cortex [GO:0005938]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; myosin V complex [GO:0031475]; myosin VI complex [GO:0031476]; nucleoplasm [GO:0005654]; rhabdomere [GO:0016028]; spindle [GO:0005819]		calcium ion binding [GO:0005509]; myosin heavy chain binding [GO:0032036]; myosin V binding [GO:0031489]; myosin VI head/neck binding [GO:0070855]
d1k35a4_d1c47a4__1		Metazoa	Proteobacteria	Chordata	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	glucose metabolic process [GO:0006006]		sarcoplasmic reticulum [GO:0016529]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1k3ca2_d5fh1a1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	gluconeogenesis [GO:0006094]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]
d1k3da2_d4ox2a1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	gluconeogenesis [GO:0006094]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]
d1k3da2_d5i67a1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; gluconeogenesis [GO:0006094]	gluconeogenesis [GO:0006094]	gluconeogenesis [GO:0006094]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]	GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]
d1k3ia1_d1j0ia1__1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1k3lb1_d3csha1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1k3na__d1khua___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; nuclear chromatin [GO:0000790]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]; co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [GO:0030618]; BMP signaling pathway [GO:0030509]; embryonic pattern specification [GO:0009880]; positive regulation of gene expression [GO:0010628]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; primary miRNA processing [GO:0031053]; protein deubiquitination [GO:0016579]; signal transduction [GO:0007165]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	BMP signaling pathway [GO:0030509]; embryonic pattern specification [GO:0009880]; positive regulation of gene expression [GO:0010628]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; primary miRNA processing [GO:0031053]; protein deubiquitination [GO:0016579]; signal transduction [GO:0007165]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; nuclear chromatin [GO:0000790]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]	co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [GO:0030618]
d1k3oa2_d2ab6d2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]
d1k3oa2_d4ivfg1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	
d1k3ob2_d3a3tb1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	
d1k3qa__d2cswa1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; ubiquitin ligase complex [GO:0000151]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone exchange [GO:0043486]; histone H2A K63-linked ubiquitination [GO:0070535]; histone H2A ubiquitination [GO:0033522]; histone H2B ubiquitination [GO:0033523]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; ubiquitin-dependent protein catabolic process [GO:0006511]	deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone exchange [GO:0043486]; histone H2A K63-linked ubiquitination [GO:0070535]; histone H2A ubiquitination [GO:0033522]; histone H2B ubiquitination [GO:0033523]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; ubiquitin ligase complex [GO:0000151]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]	chromatin binding [GO:0003682]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1k3ta2_d1t1rb4__1				Proteobacteria	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	glycosome [GO:0020015]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]
d1k3ya2_d2ljrb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d1k3yb2_d1q4ja2__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d1k3zb__d5vigz___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; cellular response to lipopolysaccharide [GO:0071222]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]	cellular response to lipopolysaccharide [GO:0071222]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; signal transduction [GO:0007165]	adaptive immune response [GO:0002250]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		
d1k42a1_d5mgca5__1		Fungi	Bacteroidetes	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]; carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]
d1k44d__d1vyai___1		Viridiplantae	Actinobacteria	Streptophyta	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]	nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]
d1k44f__d1s59b___1		Viridiplantae	Actinobacteria	Streptophyta	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1k44f__d1vyaj___1		Viridiplantae	Actinobacteria	Streptophyta	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]	nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]
d1k45a1_d1r64a1__1		Fungi	Bacteroidetes	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; xylan catabolic process [GO:0045493]	fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]	xylan catabolic process [GO:0045493]	peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]		fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1k4ca1_d4om0l2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	structural molecule activity [GO:0005198]
d1k4cb1_d1wc7h1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1k4da2_d1lo3h2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1k4db1_d1bref___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1k4db1_d2e6pa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	3M complex [GO:1990393]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; M band [GO:0031430]; perinuclear region of cytoplasm [GO:0048471]; Z disc [GO:0030018]; cytoskeletal adaptor activity [GO:0008093]; cardiac myofibril assembly [GO:0055003]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of dendrite morphogenesis [GO:0050775]; post-translational protein modification [GO:0043687]; protein localization to Golgi apparatus [GO:0034067]; regulation of mitotic nuclear division [GO:0007088]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cardiac myofibril assembly [GO:0055003]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of dendrite morphogenesis [GO:0050775]; post-translational protein modification [GO:0043687]; protein localization to Golgi apparatus [GO:0034067]; regulation of mitotic nuclear division [GO:0007088]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	3M complex [GO:1990393]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; M band [GO:0031430]; perinuclear region of cytoplasm [GO:0048471]; Z disc [GO:0030018]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cytoskeletal adaptor activity [GO:0008093]
d1k4kc__d4mula___1			Proteobacteria	Actinobacteria	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; 'de novo' NAD biosynthetic process from aspartate [GO:0034628]; NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantoate-beta-alanine ligase activity [GO:0004592]; pantothenate biosynthetic process [GO:0015940]	'de novo' NAD biosynthetic process from aspartate [GO:0034628]; NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]	pantothenate biosynthetic process [GO:0015940]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantoate-beta-alanine ligase activity [GO:0004592]
d1k4mb__d2pxha1__1			Proteobacteria	Euryarchaeota	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; 'de novo' NAD biosynthetic process from aspartate [GO:0034628]; NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	'de novo' NAD biosynthetic process from aspartate [GO:0034628]; NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]	tyrosyl-tRNA aminoacylation [GO:0006437]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]
d1k4za__d1kq5b___1	Fungi	Fungi	Ascomycota	Ascomycota	actin cortical patch [GO:0030479]; cortical actin cytoskeleton [GO:0030864]; mating projection tip [GO:0043332]; actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]; identical protein binding [GO:0042802]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; positive regulation of actin filament depolymerization [GO:0030836]; Ras protein signal transduction [GO:0007265]	actin cortical patch [GO:0030479]; cortical actin cytoskeleton [GO:0030864]; mating projection tip [GO:0043332]; actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]; identical protein binding [GO:0042802]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; positive regulation of actin filament depolymerization [GO:0030836]; Ras protein signal transduction [GO:0007265]	actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; positive regulation of actin filament depolymerization [GO:0030836]; Ras protein signal transduction [GO:0007265]	actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; positive regulation of actin filament depolymerization [GO:0030836]; Ras protein signal transduction [GO:0007265]	actin cortical patch [GO:0030479]; cortical actin cytoskeleton [GO:0030864]; mating projection tip [GO:0043332]	actin cortical patch [GO:0030479]; cortical actin cytoskeleton [GO:0030864]; mating projection tip [GO:0043332]	actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]; identical protein binding [GO:0042802]	actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]; identical protein binding [GO:0042802]
d1k59a__d2w5ma___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	extracellular region [GO:0005576]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1k5da__d1lfdb___1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1k5db__d1qqgb2__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	caveola [GO:0005901]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; insulin receptor complex [GO:0005899]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; insulin receptor binding [GO:0005158]; insulin-like growth factor receptor binding [GO:0005159]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein kinase C binding [GO:0005080]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; cellular response to fatty acid [GO:0071398]; cellular response to insulin stimulus [GO:0032869]; glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; interleukin-7-mediated signaling pathway [GO:0038111]; MAPK cascade [GO:0000165]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of insulin secretion [GO:0046676]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase B signaling [GO:0051897]; response to insulin [GO:0032868]; response to peptide hormone [GO:0043434]; signal transduction [GO:0007165]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cellular response to fatty acid [GO:0071398]; cellular response to insulin stimulus [GO:0032869]; glucose homeostasis [GO:0042593]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-7-mediated signaling pathway [GO:0038111]; MAPK cascade [GO:0000165]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of insulin secretion [GO:0046676]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase B signaling [GO:0051897]; response to insulin [GO:0032868]; response to peptide hormone [GO:0043434]; signal transduction [GO:0007165]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	caveola [GO:0005901]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; insulin receptor complex [GO:0005899]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein kinase C binding [GO:0005080]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]
d1k5db__d1xkea1__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	annulate lamellae [GO:0005642]; cytoplasm [GO:0005737]; cytoplasmic periphery of the nuclear pore complex [GO:1990723]; cytosol [GO:0005829]; host cell [GO:0043657]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear inclusion body [GO:0042405]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear pore cytoplasmic filaments [GO:0044614]; nuclear pore nuclear basket [GO:0044615]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; centrosome localization [GO:0051642]; intracellular transport of virus [GO:0075733]; mRNA export from nucleus [GO:0006406]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of GTPase activity [GO:0043547]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of gene silencing by miRNA [GO:0060964]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110]; response to amphetamine [GO:0001975]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	centrosome localization [GO:0051642]; intracellular transport of virus [GO:0075733]; mRNA export from nucleus [GO:0006406]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of GTPase activity [GO:0043547]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of gene silencing by miRNA [GO:0060964]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110]; response to amphetamine [GO:0001975]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	annulate lamellae [GO:0005642]; cytoplasm [GO:0005737]; cytoplasmic periphery of the nuclear pore complex [GO:1990723]; cytosol [GO:0005829]; host cell [GO:0043657]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear inclusion body [GO:0042405]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear pore cytoplasmic filaments [GO:0044614]; nuclear pore nuclear basket [GO:0044615]; nucleus [GO:0005634]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]
d1k5dc__d3tsrg1__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	angiogenin-PRI complex [GO:0032311]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; ribonuclease inhibitor activity [GO:0008428]; regulation of angiogenesis [GO:0045765]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	regulation of angiogenesis [GO:0045765]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	angiogenin-PRI complex [GO:0032311]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	ribonuclease inhibitor activity [GO:0008428]
d1k5gb__d2crfa1__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; R-SMAD binding [GO:0070412]; Ran GTPase binding [GO:0008536]; positive regulation of GTPase activity [GO:0043547]; protein export from nucleus [GO:0006611]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	positive regulation of GTPase activity [GO:0043547]; protein export from nucleus [GO:0006611]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	cytoplasm [GO:0005737]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	Ran GTPase binding [GO:0008536]; R-SMAD binding [GO:0070412]
d1k5gd__d3b5za1__1	Metazoa		Chordata	Proteobacteria	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]		centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	ATPase activity [GO:0016887]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]
d1k5ge__d2dfka2__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]
d1k5gf__d1fqvm2__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]
d1k5gi__d2bexa___1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	angiogenin-PRI complex [GO:0032311]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; ribonuclease inhibitor activity [GO:0008428]; mRNA catabolic process [GO:0006402]; regulation of angiogenesis [GO:0045765]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	mRNA catabolic process [GO:0006402]; regulation of angiogenesis [GO:0045765]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	angiogenin-PRI complex [GO:0032311]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	ribonuclease inhibitor activity [GO:0008428]
d1k5ha3_d1h6aa2__1			Proteobacteria	Proteobacteria	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	periplasmic space [GO:0042597]; glucose-fructose oxidoreductase activity [GO:0047061]; sorbitol biosynthetic process [GO:0006061]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	sorbitol biosynthetic process [GO:0006061]		periplasmic space [GO:0042597]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]	glucose-fructose oxidoreductase activity [GO:0047061]
d1k5mc__d4pdwa___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1k5mc__d4y5zu___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1k5na1_d2mklc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1k5na2_d4fqxa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1k5oa__d1j2ma___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; protein serine/threonine phosphatase inhibitor activity [GO:0004865]; cellular response to drug [GO:0035690]; regulation of phosphorylation [GO:0042325]	cytoplasm [GO:0005737]; protein serine/threonine phosphatase inhibitor activity [GO:0004865]; cellular response to drug [GO:0035690]; regulation of phosphorylation [GO:0042325]	cellular response to drug [GO:0035690]; regulation of phosphorylation [GO:0042325]	cellular response to drug [GO:0035690]; regulation of phosphorylation [GO:0042325]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	protein serine/threonine phosphatase inhibitor activity [GO:0004865]	protein serine/threonine phosphatase inhibitor activity [GO:0004865]
d1k5uc__d3homb1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1k5vb__d1afcb___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1k63a__d3gzja___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	polyneuridine-aldehyde esterase activity [GO:0050529]; alkaloid metabolic process [GO:0009820]	response to toxic substance [GO:0009636]	alkaloid metabolic process [GO:0009820]	periplasmic space [GO:0042597]		haloalkane dehalogenase activity [GO:0018786]	polyneuridine-aldehyde esterase activity [GO:0050529]
d1k66a1_d2flwa___1			Cyanobacteria	Proteobacteria	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]		cytoplasm [GO:0005737]		metal ion binding [GO:0046872]
d1k66a1_d4le0b___1			Cyanobacteria	Firmicutes	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]		cytoplasm [GO:0005737]		DNA binding [GO:0003677]
d1k66b1_d1chna___1			Cyanobacteria	Proteobacteria	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d1k6aa__d4jhoa1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1k6cb__d3cida___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d1k6cb__d4a4qa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1k6db__d3oxoc1__1		Metazoa	Proteobacteria	Chordata	acetate CoA-transferase activity [GO:0008775]; short-chain fatty acid metabolic process [GO:0046459]	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	short-chain fatty acid metabolic process [GO:0046459]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]		mitochondrion [GO:0005739]	acetate CoA-transferase activity [GO:0008775]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]
d1k6db__d4euba2__1			Proteobacteria	Proteobacteria	acetate CoA-transferase activity [GO:0008775]; short-chain fatty acid metabolic process [GO:0046459]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	short-chain fatty acid metabolic process [GO:0046459]	acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]			acetate CoA-transferase activity [GO:0008775]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d1k6ea__d4oyyf___1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	response to toxic substance [GO:0009636]		periplasmic space [GO:0042597]	extracellular region [GO:0005576]	haloalkane dehalogenase activity [GO:0018786]	cutinase activity [GO:0050525]
d1k6ma1_d1bifa1__1	Metazoa	Metazoa	Chordata	Chordata	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; animal organ regeneration [GO:0031100]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of glycolytic process [GO:0045820]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of glycolytic process [GO:0045821]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]	cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]	animal organ regeneration [GO:0031100]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of glycolytic process [GO:0045820]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of glycolytic process [GO:0045821]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]	fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]	cytosol [GO:0005829]	6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]	6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]
d1k6ma2_d1yfka___1	Metazoa	Metazoa	Chordata	Chordata	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; animal organ regeneration [GO:0031100]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of glycolytic process [GO:0045820]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of glycolytic process [GO:0045821]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	animal organ regeneration [GO:0031100]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of glycolytic process [GO:0045820]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of glycolytic process [GO:0045821]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]
d1k6mb2_d3k4qb___1	Metazoa	Fungi	Chordata	Ascomycota	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; animal organ regeneration [GO:0031100]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of glycolytic process [GO:0045820]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of glycolytic process [GO:0045821]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]	extracellular region [GO:0005576]; 3-phytase activity [GO:0016158]	animal organ regeneration [GO:0031100]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of glycolytic process [GO:0045820]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of glycolytic process [GO:0045821]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]		6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]	extracellular region [GO:0005576]	6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]	3-phytase activity [GO:0016158]
d1k6oc__d1egwc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; core promoter binding [GO:0001047]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coregulator activity [GO:0003712]; cell differentiation [GO:0030154]; histone H3 deacetylation [GO:0070932]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	cell differentiation [GO:0030154]; histone H3 deacetylation [GO:0070932]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; core promoter binding [GO:0001047]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coregulator activity [GO:0003712]	activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1k6ta__d5p0na___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1k6tb__d3plda___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1k6va__d5p1va___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1k6vb__d3ekwa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1k6vb__d5p57a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1k72a2_d2ylkd___1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d1k72b2_d1qbaa2__1			Firmicutes	Proteobacteria	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		periplasmic space [GO:0042597]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]
d1k73d__d1tuib1__1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	translation [GO:0006412]		ribosome [GO:0005840]	cytoplasm [GO:0005737]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1k73o__d1xnrk___1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1k78b__d3jtga___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune system process [GO:0002376]; negative regulation of cell cycle [GO:0045786]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; anatomical structure morphogenesis [GO:0009653]; blastocyst development [GO:0001824]; cell differentiation [GO:0030154]; epithelial cell differentiation [GO:0030855]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; mammary gland involution [GO:0060056]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; transcription by RNA polymerase II [GO:0006366]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune system process [GO:0002376]; negative regulation of cell cycle [GO:0045786]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	anatomical structure morphogenesis [GO:0009653]; blastocyst development [GO:0001824]; cell differentiation [GO:0030154]; epithelial cell differentiation [GO:0030855]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; mammary gland involution [GO:0060056]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]
d1k78f__d1flia___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune system process [GO:0002376]; negative regulation of cell cycle [GO:0045786]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; animal organ morphogenesis [GO:0009887]; blood circulation [GO:0008015]; cell differentiation [GO:0030154]; hemostasis [GO:0007599]; megakaryocyte development [GO:0035855]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune system process [GO:0002376]; negative regulation of cell cycle [GO:0045786]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	animal organ morphogenesis [GO:0009887]; blood circulation [GO:0008015]; cell differentiation [GO:0030154]; hemostasis [GO:0007599]; megakaryocyte development [GO:0035855]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d1k7ca__d5jd3b1__1	Fungi		Ascomycota		hydrolase activity [GO:0016787]						hydrolase activity [GO:0016787]	
d1k7ga2_d1ka4a___1			Proteobacteria	Euryarchaeota	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	cobalt ion binding [GO:0050897]; metallocarboxypeptidase activity [GO:0004181]; proteolysis [GO:0006508]		proteolysis [GO:0006508]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	cobalt ion binding [GO:0050897]; metallocarboxypeptidase activity [GO:0004181]
d1k7ia2_d1kapp2__1			Proteobacteria	Proteobacteria	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]; negative regulation of complement activation, classical pathway [GO:0045959]; negative regulation of complement activation, lectin pathway [GO:0001869]; pathogenesis [GO:0009405]; positive regulation of sodium ion transport [GO:0010765]		negative regulation of complement activation, classical pathway [GO:0045959]; negative regulation of complement activation, lectin pathway [GO:0001869]; pathogenesis [GO:0009405]; positive regulation of sodium ion transport [GO:0010765]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]
d1k7ia2_d3ftwa2__1		Metazoa	Proteobacteria	Chordata	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1k7qa1_d3u1ra2__1			Proteobacteria	Bacteroidetes	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]			extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1k7qa2_d1go8p2__1			Proteobacteria	Proteobacteria	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]			extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1k7qa2_d4h49a1__1		Metazoa	Proteobacteria	Chordata	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1k7wb__d1tjvb___1	Metazoa	Metazoa	Chordata	Chordata	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]			argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]
d1k7wc__d1jswd___1	Metazoa		Chordata	Proteobacteria	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	cytosol [GO:0005829]; membrane [GO:0016020]; aspartate ammonia-lyase activity [GO:0008797]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; tricarboxylic acid cycle [GO:0006099]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; membrane [GO:0016020]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]	aspartate ammonia-lyase activity [GO:0008797]
d1k7wd__d1hy0b___1	Metazoa	Metazoa	Chordata	Chordata	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	catalytic activity [GO:0003824]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process via ornithine [GO:0042450]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	arginine biosynthetic process via ornithine [GO:0042450]			argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]	catalytic activity [GO:0003824]; structural constituent of eye lens [GO:0005212]
d1k7xb__d1j0bh___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]	tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]
d1k82a2_d3gq5a1__1			Proteobacteria	Firmicutes	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA N-glycosylase activity [GO:0019104]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [GO:0000703]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]			8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA N-glycosylase activity [GO:0019104]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [GO:0000703]; zinc ion binding [GO:0008270]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]
d1k82d2_d3sata1__1			Proteobacteria	Firmicutes	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA N-glycosylase activity [GO:0019104]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [GO:0000703]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]			8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA N-glycosylase activity [GO:0019104]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [GO:0000703]; zinc ion binding [GO:0008270]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]
d1k87a4_d4jnya2__1				Proteobacteria		cytoplasmic side of plasma membrane [GO:0009898]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]; proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]		proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]		cytoplasmic side of plasma membrane [GO:0009898]		1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]
d1k89a1_d1pl7b2__1		Metazoa	Firmicutes	Chordata	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; motile cilium [GO:0031514]; (R,R)-butanediol dehydrogenase activity [GO:0000721]; carbohydrate binding [GO:0030246]; D-xylulose reductase activity [GO:0046526]; identical protein binding [GO:0042802]; L-iditol 2-dehydrogenase activity [GO:0003939]; NAD binding [GO:0051287]; ribitol 2-dehydrogenase activity [GO:0050255]; zinc ion binding [GO:0008270]; flagellated sperm motility [GO:0030317]; fructose biosynthetic process [GO:0046370]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; L-xylitol catabolic process [GO:0051160]; L-xylitol metabolic process [GO:0051164]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; sorbitol catabolic process [GO:0006062]	cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	flagellated sperm motility [GO:0030317]; fructose biosynthetic process [GO:0046370]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; L-xylitol catabolic process [GO:0051160]; L-xylitol metabolic process [GO:0051164]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; sorbitol catabolic process [GO:0006062]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; motile cilium [GO:0031514]	glutamate dehydrogenase (NAD+) activity [GO:0004352]	(R,R)-butanediol dehydrogenase activity [GO:0000721]; carbohydrate binding [GO:0030246]; D-xylulose reductase activity [GO:0046526]; identical protein binding [GO:0042802]; L-iditol 2-dehydrogenase activity [GO:0003939]; NAD binding [GO:0051287]; ribitol 2-dehydrogenase activity [GO:0050255]; zinc ion binding [GO:0008270]
d1k8da1_d5i76a1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1k8db__d5jqdb2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1k8ec1_d4xr5b1__1				Proteobacteria		cytosol [GO:0005829]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]		pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]		cytosol [GO:0005829]		phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1k8ed1_d2wk6a1__1		Metazoa		Chordata		cytosol [GO:0005829]; growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]		angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]		cytosol [GO:0005829]		growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1k8ed2_d5ep8b2__1				Firmicutes		cytosol [GO:0005829]; metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]		pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]		cytosol [GO:0005829]		metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1k8fc__d1k4zb___1	Metazoa	Fungi	Chordata	Ascomycota	azurophil granule lumen [GO:0035578]; cortical actin cytoskeleton [GO:0030864]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]; actin polymerization or depolymerization [GO:0008154]; activation of adenylate cyclase activity [GO:0007190]; ameboidal-type cell migration [GO:0001667]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; neutrophil degranulation [GO:0043312]; receptor-mediated endocytosis [GO:0006898]; signal transduction [GO:0007165]	actin cortical patch [GO:0030479]; cortical actin cytoskeleton [GO:0030864]; mating projection tip [GO:0043332]; actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]; identical protein binding [GO:0042802]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; positive regulation of actin filament depolymerization [GO:0030836]; Ras protein signal transduction [GO:0007265]	actin polymerization or depolymerization [GO:0008154]; activation of adenylate cyclase activity [GO:0007190]; ameboidal-type cell migration [GO:0001667]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; neutrophil degranulation [GO:0043312]; receptor-mediated endocytosis [GO:0006898]; signal transduction [GO:0007165]	actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; positive regulation of actin filament depolymerization [GO:0030836]; Ras protein signal transduction [GO:0007265]	azurophil granule lumen [GO:0035578]; cortical actin cytoskeleton [GO:0030864]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]	actin cortical patch [GO:0030479]; cortical actin cytoskeleton [GO:0030864]; mating projection tip [GO:0043332]	actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]	actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]; identical protein binding [GO:0042802]
d1k8fd__d2b0ra___1	Metazoa		Chordata	Apicomplexa	azurophil granule lumen [GO:0035578]; cortical actin cytoskeleton [GO:0030864]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]; actin polymerization or depolymerization [GO:0008154]; activation of adenylate cyclase activity [GO:0007190]; ameboidal-type cell migration [GO:0001667]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; neutrophil degranulation [GO:0043312]; receptor-mediated endocytosis [GO:0006898]; signal transduction [GO:0007165]	actin binding [GO:0003779]; cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]	actin polymerization or depolymerization [GO:0008154]; activation of adenylate cyclase activity [GO:0007190]; ameboidal-type cell migration [GO:0001667]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; neutrophil degranulation [GO:0043312]; receptor-mediated endocytosis [GO:0006898]; signal transduction [GO:0007165]	cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]	azurophil granule lumen [GO:0035578]; cortical actin cytoskeleton [GO:0030864]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]		actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]	actin binding [GO:0003779]
d1k8gb2_d1ph4b___1			Ciliophora	Ciliophora	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	telomere capping [GO:0016233]	telomere capping [GO:0016233]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1k8gc2_d2mnaa1__1			Ciliophora	Crenarchaeota	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	DNA binding [GO:0003677]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle checkpoint [GO:0007093]; response to ionizing radiation [GO:0010212]	telomere capping [GO:0016233]	double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle checkpoint [GO:0007093]; response to ionizing radiation [GO:0010212]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]		protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	DNA binding [GO:0003677]
d1k8ia1_d1ospl2__1	Metazoa	Metazoa	Chordata	Chordata	endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; MHC class II protein complex binding [GO:0023026]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; chaperone cofactor-dependent protein refolding [GO:0051085]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; chaperone cofactor-dependent protein refolding [GO:0051085]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	MHC class II protein complex binding [GO:0023026]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1k8ia1_d2ai0m1__1	Metazoa	Metazoa	Chordata	Chordata	endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; MHC class II protein complex binding [GO:0023026]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; chaperone cofactor-dependent protein refolding [GO:0051085]		adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; chaperone cofactor-dependent protein refolding [GO:0051085]		endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]		MHC class II protein complex binding [GO:0023026]	
d1k8ib1_d1mjjh1__1	Metazoa		Chordata		endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; MHC class II protein complex binding [GO:0023026]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; chaperone cofactor-dependent protein refolding [GO:0051085]		adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; chaperone cofactor-dependent protein refolding [GO:0051085]		endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]		MHC class II protein complex binding [GO:0023026]	
d1k8ib2_d1kj2h2__1	Metazoa	Metazoa	Chordata	Chordata	endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; MHC class II protein complex binding [GO:0023026]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; chaperone cofactor-dependent protein refolding [GO:0051085]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; chaperone cofactor-dependent protein refolding [GO:0051085]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	MHC class II protein complex binding [GO:0023026]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1k8kb1_d1g99a2__1	Metazoa		Chordata	Euryarchaeota	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	actin filament binding [GO:0051015]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]
d1k8wa5_d2ab4a2__1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; mitochondrion [GO:0005739]; pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]; mRNA pseudouridine synthesis [GO:1990481]; pseudouridine synthesis [GO:0001522]; RNA folding [GO:0034337]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	mitochondrion [GO:0005739]; pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]; mRNA pseudouridine synthesis [GO:1990481]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	mRNA pseudouridine synthesis [GO:1990481]; pseudouridine synthesis [GO:0001522]; RNA folding [GO:0034337]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	mRNA pseudouridine synthesis [GO:1990481]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]	pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]
d1k90f__d1psrb___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d1k92a2_d4u7ja2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; arginine biosynthetic process [GO:0006526]; argininosuccinate metabolic process [GO:0000053]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]	arginine biosynthetic process [GO:0006526]; argininosuccinate metabolic process [GO:0000053]; urea cycle [GO:0000050]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]
d1k93d__d1igva___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]
d1k94a__d1xk4a1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; membrane fusion [GO:0061025]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	membrane fusion [GO:0061025]; neutrophil degranulation [GO:0043312]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1k94b__d2jc2c___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; membrane fusion [GO:0061025]; neutrophil degranulation [GO:0043312]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]; action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	membrane fusion [GO:0061025]; neutrophil degranulation [GO:0043312]	action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]
d1k97a1_d1t9gs___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; arginine biosynthetic process [GO:0006526]; argininosuccinate metabolic process [GO:0000053]; urea cycle [GO:0000050]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	arginine biosynthetic process [GO:0006526]; argininosuccinate metabolic process [GO:0000053]; urea cycle [GO:0000050]	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	electron transfer activity [GO:0009055]
d1k98a2_d4reqc2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cobalamin binding [GO:0031419]; methionine synthase activity [GO:0008705]; protein methyltransferase activity [GO:0008276]; zinc ion binding [GO:0008270]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		cobalamin binding [GO:0031419]; methionine synthase activity [GO:0008705]; protein methyltransferase activity [GO:0008276]; zinc ion binding [GO:0008270]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d1k99a__d3nm9a___1	Metazoa	Metazoa	Chordata	Arthropoda	fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA binding [GO:0003723]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]; RNA polymerase I upstream control element sequence-specific DNA binding [GO:0001165]; scaffold protein binding [GO:0097110]; positive regulation of transcription by RNA polymerase I [GO:0045943]; regulation of transcription by RNA polymerase I [GO:0006356]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase I [GO:0006360]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]; chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	positive regulation of transcription by RNA polymerase I [GO:0045943]; regulation of transcription by RNA polymerase I [GO:0006356]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase I [GO:0006360]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]	chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA binding [GO:0003723]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]; RNA polymerase I upstream control element sequence-specific DNA binding [GO:0001165]; scaffold protein binding [GO:0097110]	AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]
d1k9ae2_d1bhfa___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]
d1k9af2_d1oplb1__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]
d1k9da2_d1m03a2__1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; xylan catabolic process [GO:0045493]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]	beta-N-acetylhexosaminidase activity [GO:0004563]
d1k9ib__d4uxma___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]	carbohydrate binding [GO:0030246]
d1k9if__d1tlga___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	carbohydrate binding [GO:0030246]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]	carbohydrate binding [GO:0030246]
d1k9ih__d2ridc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1k9ij__d3cdge1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1k9ja__d1bcj11__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; calcium-dependent protein binding [GO:0048306]; carbohydrate binding [GO:0030246]; ICAM-3 receptor activity [GO:0030369]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; signaling receptor activity [GO:0038023]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	calcium-dependent protein binding [GO:0048306]; carbohydrate binding [GO:0030246]; ICAM-3 receptor activity [GO:0030369]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; signaling receptor activity [GO:0038023]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d1k9ja__d3p7fd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; calcium-dependent protein binding [GO:0048306]; carbohydrate binding [GO:0030246]; ICAM-3 receptor activity [GO:0030369]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; signaling receptor activity [GO:0038023]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium-dependent protein binding [GO:0048306]; carbohydrate binding [GO:0030246]; ICAM-3 receptor activity [GO:0030369]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; signaling receptor activity [GO:0038023]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1k9kb__d1kcya___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; ion transmembrane transporter activity [GO:0015075]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tropomyosin binding [GO:0005523]; zinc ion binding [GO:0008270]; axonogenesis [GO:0007409]; positive regulation of fibroblast proliferation [GO:0048146]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	axonogenesis [GO:0007409]; positive regulation of fibroblast proliferation [GO:0048146]; signal transduction [GO:0007165]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; ion transmembrane transporter activity [GO:0015075]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tropomyosin binding [GO:0005523]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]
d1k9kb__d3cr4x___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; ion transmembrane transporter activity [GO:0015075]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tropomyosin binding [GO:0005523]; zinc ion binding [GO:0008270]; axonogenesis [GO:0007409]; positive regulation of fibroblast proliferation [GO:0048146]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	axonogenesis [GO:0007409]; positive regulation of fibroblast proliferation [GO:0048146]; signal transduction [GO:0007165]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; ion transmembrane transporter activity [GO:0015075]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tropomyosin binding [GO:0005523]; zinc ion binding [GO:0008270]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1k9md__d2i2vd1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1k9md__d3u6kb2__1			Euryarchaeota	Actinobacteria	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	extracellular region [GO:0005576]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	translation [GO:0006412]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	ribosome [GO:0005840]	extracellular region [GO:0005576]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1k9mg2_d1q86g1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1k9oe__d1k1pa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1k9pa__d1y1xa___1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; ion transmembrane transporter activity [GO:0015075]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tropomyosin binding [GO:0005523]; zinc ion binding [GO:0008270]; axonogenesis [GO:0007409]; positive regulation of fibroblast proliferation [GO:0048146]; signal transduction [GO:0007165]	calcium ion binding [GO:0005509]	axonogenesis [GO:0007409]; positive regulation of fibroblast proliferation [GO:0048146]; signal transduction [GO:0007165]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; ion transmembrane transporter activity [GO:0015075]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tropomyosin binding [GO:0005523]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]
d1k9sd__d5tbsa___1		Metazoa	Proteobacteria	Platyhelminthes	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]; membrane [GO:0016020]		identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d1k9ta1_d1ea9d1__1			Proteobacteria	Firmicutes	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cyclomaltodextrinase activity [GO:0047798]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			chitinase activity [GO:0004568]; chitin binding [GO:0008061]	cyclomaltodextrinase activity [GO:0047798]
d1k9xa__d4fu4a1__1		Metazoa	Euryarchaeota	Chordata	cobalt ion binding [GO:0050897]; metallocarboxypeptidase activity [GO:0004181]; proteolysis [GO:0006508]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	proteolysis [GO:0006508]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cobalt ion binding [GO:0050897]; metallocarboxypeptidase activity [GO:0004181]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1kaba__d4h7ba___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1kaka__d2r0ba___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; F-box domain binding [GO:1990444]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; pseudophosphatase activity [GO:0001691]; MAPK export from nucleus [GO:0045204]; negative regulation of catalytic activity [GO:0043086]; negative regulation of protein binding [GO:0032091]; negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process [GO:0062026]; regulation of ERK1 and ERK2 cascade [GO:0070372]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	MAPK export from nucleus [GO:0045204]; negative regulation of catalytic activity [GO:0043086]; negative regulation of protein binding [GO:0032091]; negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process [GO:0062026]; regulation of ERK1 and ERK2 cascade [GO:0070372]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	F-box domain binding [GO:1990444]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; pseudophosphatase activity [GO:0001691]
d1kana1_d1knya1__1			Firmicutes	Firmicutes	nucleotidyltransferase activity [GO:0016779]; response to antibiotic [GO:0046677]	nucleotidyltransferase activity [GO:0016779]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]			nucleotidyltransferase activity [GO:0016779]	nucleotidyltransferase activity [GO:0016779]
d1kana2_d3c66b2__1		Fungi	Firmicutes	Ascomycota	nucleotidyltransferase activity [GO:0016779]; response to antibiotic [GO:0046677]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	response to antibiotic [GO:0046677]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]		mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]	nucleotidyltransferase activity [GO:0016779]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d1kaqb__d5h4vd1__1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	NAD biosynthetic process [GO:0009435]	glutamyl-tRNA aminoacylation [GO:0006424]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1kaqc__d3otwf___1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	NAD biosynthetic process [GO:0009435]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1kasa2_d1dlvb2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1kaua__d2fvhb___1				Actinobacteria		cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]		urea catabolic process [GO:0043419]		cytoplasm [GO:0005737]		nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d1kaxa1_d2j4ra1__1	Metazoa		Chordata	Aquificae	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	metal ion binding [GO:0046872]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]		autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	metal ion binding [GO:0046872]
d1kaxa2_d2gtdc1__1	Metazoa		Chordata	Thermotogae	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	coenzyme A biosynthetic process [GO:0015937]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d1kaya2_d2e88a2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]
d1kaza1_d3mk6d2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; nucleus [GO:0005634]; acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]; coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytosol [GO:0005829]; nucleus [GO:0005634]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]
d1kaza2_d5ce3a2__1	Metazoa		Chordata	Proteobacteria	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]		autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]
d1kb0a1_d5h2fv___1			Proteobacteria	Cyanobacteria	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; calcium ion binding [GO:0005509]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]	integral component of membrane [GO:0016021]; photosystem II [GO:0009523]; thylakoid membrane [GO:0042651]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	integral component of membrane [GO:0016021]; photosystem II [GO:0009523]; thylakoid membrane [GO:0042651]	calcium ion binding [GO:0005509]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]	
d1kb5h1_d1onqa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1kb5l1_d4ma1f1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kb5l2_d2fecl1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1kb5l2_d2x4pb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1kb9a1_d3h1ho1__1	Fungi	Metazoa	Ascomycota	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1kb9j__d1yuhb2__1	Fungi		Ascomycota		integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]			
d1kb9k__d4xakl1__1	Fungi		Ascomycota		integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		
d1kbca__d5fssa___1	Metazoa		Chordata	Firmicutes	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]		collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1kbgl__d3s34l2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1kbka2_d5hnna1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1kbnb1_d2vcvl2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d1kbob__d3ojxa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1kbod__d3gfqc___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytosol [GO:0005829]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d1kbpa2_d5inba___1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; protein-containing complex [GO:0032991]; PTW/PP1 phosphatase complex [GO:0072357]; lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]		cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]	extracellular region [GO:0005576]	cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]
d1kbpb2_d2nymc1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]		apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	extracellular region [GO:0005576]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]
d1kbqa__d1qr2a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1kbqa__d1rtta___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; protein homodimerization activity [GO:0042803]; oxidation-reduction process [GO:0055114]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytosol [GO:0005829]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; protein homodimerization activity [GO:0042803]
d1kbqb__d3gfsd___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytosol [GO:0005829]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d1kbqc__d3f90b___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1kbqc__d3uxea___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1kbqd__d3qfca1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1kbva2_d1v55b1__1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	nitrogen compound metabolic process [GO:0006807]	ATP synthesis coupled electron transport [GO:0042773]	cell outer membrane [GO:0009279]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1kbvb1_d2jfca2__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	cell outer membrane [GO:0009279]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1kbvc2_d4yl4a___1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	nitrogen compound metabolic process [GO:0006807]		cell outer membrane [GO:0009279]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1kbvd2_d2ft6a___1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	cell outer membrane [GO:0009279]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1kbve1_d5n0ka3__1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	anchored component of plasma membrane [GO:0046658]; cell [GO:0005623]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; aging [GO:0007568]; cellular iron ion homeostasis [GO:0006879]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; liver development [GO:0001889]; lung development [GO:0030324]; plasma membrane copper ion transport [GO:0015679]; response to copper ion [GO:0046688]; response to nutrient [GO:0007584]	nitrogen compound metabolic process [GO:0006807]	aging [GO:0007568]; cellular iron ion homeostasis [GO:0006879]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; liver development [GO:0001889]; lung development [GO:0030324]; plasma membrane copper ion transport [GO:0015679]; response to copper ion [GO:0046688]; response to nutrient [GO:0007584]	cell outer membrane [GO:0009279]	anchored component of plasma membrane [GO:0046658]; cell [GO:0005623]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d1kbve2_d1nifa2__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cell outer membrane [GO:0009279]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1kbvf2_d4ev3b2__1			Proteobacteria		cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]		cell outer membrane [GO:0009279]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	
d1kbwa1_d1qnif1__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	membrane [GO:0016020]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	nitrogen compound metabolic process [GO:0006807]		cell outer membrane [GO:0009279]	membrane [GO:0016020]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d1kbwb1_d5ehfa1__1		Fungi	Proteobacteria	Basidiomycota	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	nitrogen compound metabolic process [GO:0006807]		cell outer membrane [GO:0009279]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1kbwb2_d5ue6d2__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	cell outer membrane [GO:0009279]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1kbwc1_d5n8ia2__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cell outer membrane [GO:0009279]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1kbwd2_d2wsda3__1			Proteobacteria	Firmicutes	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	nitrogen compound metabolic process [GO:0006807]	sporulation resulting in formation of a cellular spore [GO:0030435]	cell outer membrane [GO:0009279]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1kbwe1_d3n2jd___1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	cell outer membrane [GO:0009279]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1kbwe2_d1et8a2__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cell outer membrane [GO:0009279]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1kbwe2_d5b1jc___1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	cell outer membrane [GO:0009279]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1kc0a__d4o6vc1__1				Proteobacteria								
d1kc0a__d5i7fl___1				Proteobacteria		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]				enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d1kc5h1_d1q9ra3__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kc5h2_d5j89a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kc8d__d4lbza2__1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	translation [GO:0006412]		ribosome [GO:0005840]	cytoplasm [GO:0005737]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1kc8e__d2hguf1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1kc8l__d2gyai1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1kcab__d3k2zb2__1				Thermotogae	virion [GO:0019012]; core promoter binding [GO:0001047]; identical protein binding [GO:0042802]; latency-replication decision [GO:0098689]; maintenance of viral latency [GO:0019044]; negative regulation of transcription by competitive promoter binding [GO:0010944]; positive regulation of viral transcription [GO:0050434]	DNA binding [GO:0003677]; serine-type endopeptidase activity [GO:0004252]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]	latency-replication decision [GO:0098689]; maintenance of viral latency [GO:0019044]; negative regulation of transcription by competitive promoter binding [GO:0010944]; positive regulation of viral transcription [GO:0050434]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]	virion [GO:0019012]		core promoter binding [GO:0001047]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; serine-type endopeptidase activity [GO:0004252]
d1kcad__d3k2za2__1				Thermotogae	virion [GO:0019012]; core promoter binding [GO:0001047]; identical protein binding [GO:0042802]; latency-replication decision [GO:0098689]; maintenance of viral latency [GO:0019044]; negative regulation of transcription by competitive promoter binding [GO:0010944]; positive regulation of viral transcription [GO:0050434]	DNA binding [GO:0003677]; serine-type endopeptidase activity [GO:0004252]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]	latency-replication decision [GO:0098689]; maintenance of viral latency [GO:0019044]; negative regulation of transcription by competitive promoter binding [GO:0010944]; positive regulation of viral transcription [GO:0050434]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]	virion [GO:0019012]		core promoter binding [GO:0001047]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; serine-type endopeptidase activity [GO:0004252]
d1kcba1_d2afna2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1kcba2_d2xx1f2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1kcba2_d3t6vb2__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1kcda__d2bspa___1	Fungi		Basidiomycota	Firmicutes	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]
d1kcea1_d4iqqd___1		Metazoa	Proteobacteria	Nematoda (roundworms)	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]	cytosol [GO:0005829]		magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d1kcga__d3p5db___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; MHC class I protein binding [GO:0042288]; MHC class Ib receptor activity [GO:0032394]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; MHC class Ib receptor activity [GO:0032394]; MHC class I protein binding [GO:0042288]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1kcgb__d3bc6a___1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; MHC class I protein binding [GO:0042288]; MHC class Ib receptor activity [GO:0032394]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]		adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; MHC class Ib receptor activity [GO:0032394]; MHC class I protein binding [GO:0042288]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]	
d1kcka1_d1hh4e___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	carbohydrate metabolic process [GO:0005975]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	extracellular region [GO:0005576]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]
d1kcka2_d1qhoa2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1kcka3_d3dhpa1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d1kcka4_d4x0ve___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1kcla1_d1wzlb1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1kcqa__d3l50b1__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cortical patch [GO:0030479]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; Arp2/3 complex binding [GO:0071933]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; protein kinase inhibitor activity [GO:0004860]; actin filament debranching [GO:0071846]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; neutrophil degranulation [GO:0043312]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament debranching [GO:0071846]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; neutrophil degranulation [GO:0043312]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cortical patch [GO:0030479]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; Arp2/3 complex binding [GO:0071933]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; protein kinase inhibitor activity [GO:0004860]
d1kcrh1_d5f8rc1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kcrh2_d1nakl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1kcrl2_d2ih3a1__1	Metazoa		Chordata	Actinobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	voltage-gated potassium channel complex [GO:0008076]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1kcsh2_d3qiuc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kcsh2_d4xbpf2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kcsl2_d3bw9b2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1kcsl2_d4h0hb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kcuh1_d3stba1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	kinetoplast [GO:0020023]; mitochondrion [GO:0005739]; 3'-5'-exoribonuclease activity [GO:0000175]; endoribonuclease activity, producing 5'-phosphomonoesters [GO:0016891]; nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]; mRNA modification [GO:0016556]; response to metal ion [GO:0010038]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	mRNA modification [GO:0016556]; response to metal ion [GO:0010038]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	kinetoplast [GO:0020023]; mitochondrion [GO:0005739]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	3'-5'-exoribonuclease activity [GO:0000175]; endoribonuclease activity, producing 5'-phosphomonoesters [GO:0016891]; nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]
d1kcvl1_d4kaql2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kcwa1_d1kyad3__1	Metazoa	Fungi	Chordata	Basidiomycota	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]		chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1kcwa2_d2i7sa___1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	oxidation-reduction process [GO:0055114]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1kcwa4_d1pzba___1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1kcxb2_d1ndya___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; growth cone [GO:0030426]; midbody [GO:0030496]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; spindle [GO:0005819]; filamin binding [GO:0031005]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [GO:0016812]; identical protein binding [GO:0042802]; phosphoprotein binding [GO:0051219]; axon guidance [GO:0007411]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of actin filament binding [GO:1904530]; negative regulation of neuron projection development [GO:0010977]; semaphorin-plexin signaling pathway [GO:0071526]	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]; adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	axon guidance [GO:0007411]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of actin filament binding [GO:1904530]; negative regulation of neuron projection development [GO:0010977]; semaphorin-plexin signaling pathway [GO:0071526]	adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	actin cytoskeleton [GO:0015629]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; growth cone [GO:0030426]; midbody [GO:0030496]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; spindle [GO:0005819]	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]	filamin binding [GO:0031005]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [GO:0016812]; identical protein binding [GO:0042802]; phosphoprotein binding [GO:0051219]	adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]
d1kcya__d1k31a___1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]				apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]		calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	
d1kcza2_d4kema1__1			Firmicutes	Proteobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]; glutamate catabolic process via L-citramalate [GO:0019553]	D(-)-tartrate dehydratase activity [GO:0047808]; metal ion binding [GO:0046872]	glutamate catabolic process via L-citramalate [GO:0019553]				cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]	D(-)-tartrate dehydratase activity [GO:0047808]; metal ion binding [GO:0046872]
d1kcza2_d4zcwb1__1		Metazoa	Firmicutes	Chordata	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]; glutamate catabolic process via L-citramalate [GO:0019553]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glutamate catabolic process via L-citramalate [GO:0019553]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1kczb2_d4kemb1__1			Firmicutes	Proteobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]; glutamate catabolic process via L-citramalate [GO:0019553]	D(-)-tartrate dehydratase activity [GO:0047808]; metal ion binding [GO:0046872]	glutamate catabolic process via L-citramalate [GO:0019553]				cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]	D(-)-tartrate dehydratase activity [GO:0047808]; metal ion binding [GO:0046872]
d1kd1c1_d3df4c1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1kd1e__d3df2e1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1kd1g1_d2b9nh1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1kd1g2_d2otje1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1kd1q__d1vqpp1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1kd1s__d2qozs1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1kd2a__d1mtia___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1kd2d__d2uunl___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1kd7c__d5h4ba___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell junction [GO:0030054]; extracellular space [GO:0005615]; synapse [GO:0045202]; protein secretion [GO:0009306]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	protein secretion [GO:0009306]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; extracellular space [GO:0005615]; synapse [GO:0045202]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	
d1kdfa__d1b7ka___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]	extracellular region [GO:0005576]			extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1kdgb2_d1b4va2__1	Fungi		Basidiomycota	Actinobacteria	extracellular region [GO:0005576]; cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	cellulose catabolic process [GO:0030245]	cholesterol metabolic process [GO:0008203]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]
d1kdha1_d2bcra1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d1kdha1_d8icva1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d1kdia__d1asqa1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]			chloroplast thylakoid membrane [GO:0009535]	extracellular region [GO:0005576]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]
d1kdq.1_d3tiua___1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; lysosome [GO:0005764]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; positive regulation of apoptotic process [GO:0043065]; protein catabolic process [GO:0030163]; response to cytokine [GO:0034097]; response to food [GO:0032094]; response to nutrient [GO:0007584]; response to peptide hormone [GO:0043434]; response to toxic substance [GO:0009636]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; positive regulation of apoptotic process [GO:0043065]; protein catabolic process [GO:0030163]; response to cytokine [GO:0034097]; response to food [GO:0032094]; response to nutrient [GO:0007584]; response to peptide hormone [GO:0043434]; response to toxic substance [GO:0009636]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; lysosome [GO:0005764]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1kdtb__d2jdia3__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; pantoate-beta-alanine ligase activity [GO:0004592]; nucleobase-containing small molecule interconversion [GO:0015949]; pantothenate biosynthetic process from valine [GO:0033317]; pyrimidine nucleotide metabolic process [GO:0006220]; response to X-ray [GO:0010165]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	nucleobase-containing small molecule interconversion [GO:0015949]; pantothenate biosynthetic process from valine [GO:0033317]; pyrimidine nucleotide metabolic process [GO:0006220]; response to X-ray [GO:0010165]	ATP synthesis coupled proton transport [GO:0015986]	cytosol [GO:0005829]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; pantoate-beta-alanine ligase activity [GO:0004592]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1kdya__d3f49s___1				Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1keaa__d4ai4a___1			Euryarchaeota		4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]		base-excision repair [GO:0006284]				4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; metal ion binding [GO:0046872]	
d1kebb__d5l71a___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; glutathione peroxidase activity [GO:0004602]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; phospholipid-hydroperoxide glutathione peroxidase activity [GO:0047066]; selenium binding [GO:0008430]; aging [GO:0007568]; chromatin organization [GO:0006325]; glutathione metabolic process [GO:0006749]; multicellular organism development [GO:0007275]; negative regulation of ferroptosis [GO:0110076]; protein polymerization [GO:0051258]; regulation of inflammatory response [GO:0050727]; response to estradiol [GO:0032355]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	aging [GO:0007568]; chromatin organization [GO:0006325]; glutathione metabolic process [GO:0006749]; multicellular organism development [GO:0007275]; negative regulation of ferroptosis [GO:0110076]; protein polymerization [GO:0051258]; regulation of inflammatory response [GO:0050727]; response to estradiol [GO:0032355]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	glutathione peroxidase activity [GO:0004602]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; phospholipid-hydroperoxide glutathione peroxidase activity [GO:0047066]; selenium binding [GO:0008430]
d1keda__d1thaa___1		Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]		cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]		hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1keea2_d2iu3b1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1keec2_d2iu3a1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1keec4_d4o4jf1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1keec5_d3rv3a2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1keee2_d1thza1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1keee3_d1kjja2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d1keeg3_d1ulza2__1			Proteobacteria	Aquificae	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]		carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]
d1keeg3_d5ng1f1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1keeg4_d3ethb2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]
d1kegl2_d2hmic1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1keka2_d5dx6b3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; butanediol metabolic process [GO:0034077]	electron transport chain [GO:0022900]	butanediol metabolic process [GO:0034077]	cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1kekb1_d3fznc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	electron transport chain [GO:0022900]	mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1kekb3_d3dvad2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	electron transport chain [GO:0022900]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1kekb5_d1jnrd___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]	electron transport chain [GO:0022900]		cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]
d1kelh2_d2edla1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]
d1kemh1_d2e7lb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kemh1_d2wqrb2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1kemh2_d3g5za2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kene__d4lcxa___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1kenl1_d3d2uf___1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell surface receptor binding [GO:0046789]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1kenu1_d2vlje2__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell surface receptor binding [GO:0046789]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1kenu2_d4leob1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; neuregulin binding [GO:0038132]; neuregulin receptor activity [GO:0038131]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activator activity [GO:0030296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; cranial nerve development [GO:0021545]; endocardial cushion development [GO:0003197]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; negative regulation of cell adhesion [GO:0007162]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of secretion [GO:0051048]; negative regulation of signal transduction [GO:0009968]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cardiac muscle tissue development [GO:0055025]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein tyrosine kinase activity [GO:0061098]; regulation of cell motility [GO:2000145]; regulation of cell population proliferation [GO:0042127]; Schwann cell differentiation [GO:0014037]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cranial nerve development [GO:0021545]; endocardial cushion development [GO:0003197]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; negative regulation of cell adhesion [GO:0007162]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of secretion [GO:0051048]; negative regulation of signal transduction [GO:0009968]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cardiac muscle tissue development [GO:0055025]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein tyrosine kinase activity [GO:0061098]; regulation of cell motility [GO:2000145]; regulation of cell population proliferation [GO:0042127]; Schwann cell differentiation [GO:0014037]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	host cell surface receptor binding [GO:0046789]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; neuregulin binding [GO:0038132]; neuregulin receptor activity [GO:0038131]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activator activity [GO:0030296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]
d1keob__d2l2ga1__1	Metazoa	Metazoa	Chordata	Chordata	endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]; protein domain specific binding [GO:0019904]; retromer complex binding [GO:1905394]; lysosomal transport [GO:0007041]; protein targeting to lysosome [GO:0006622]; secretion of lysosomal enzymes [GO:0033299]	cell surface [GO:0009986]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; nuclear envelope lumen [GO:0005641]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; identical protein binding [GO:0042802]; insulin-like growth factor binding [GO:0005520]; mannose binding [GO:0005537]; phosphoprotein binding [GO:0051219]; signaling receptor activity [GO:0038023]; lysosomal transport [GO:0007041]; positive regulation by host of viral process [GO:0044794]	lysosomal transport [GO:0007041]; protein targeting to lysosome [GO:0006622]; secretion of lysosomal enzymes [GO:0033299]	lysosomal transport [GO:0007041]; positive regulation by host of viral process [GO:0044794]	endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]	cell surface [GO:0009986]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; nuclear envelope lumen [GO:0005641]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	protein domain specific binding [GO:0019904]; retromer complex binding [GO:1905394]	identical protein binding [GO:0042802]; insulin-like growth factor binding [GO:0005520]; mannose binding [GO:0005537]; phosphoprotein binding [GO:0051219]; signaling receptor activity [GO:0038023]
d1kepb__d4m8sc___1			Firmicutes	Proteobacteria	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]; nucleotide-sugar metabolic process [GO:0009225]	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; fatty acid biosynthetic process [GO:0006633]	nucleotide-sugar metabolic process [GO:0009225]	fatty acid biosynthetic process [GO:0006633]			dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]
d1keqa__d3p4va___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; gluconeogenesis [GO:0006094]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	gluconeogenesis [GO:0006094]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	mitochondrion [GO:0005739]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1keqb__d1rzda___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; gluconeogenesis [GO:0006094]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	gluconeogenesis [GO:0006094]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	mitochondrion [GO:0005739]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1kera__d2bgla___1		Viridiplantae	Firmicutes	Streptophyta	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]; nucleotide-sugar metabolic process [GO:0009225]	(-)-secoisolariciresinol dehydrogenase activity [GO:0102911]; nucleotide binding [GO:0000166]; lignan biosynthetic process [GO:0009807]; protein homotetramerization [GO:0051289]	nucleotide-sugar metabolic process [GO:0009225]	lignan biosynthetic process [GO:0009807]; protein homotetramerization [GO:0051289]			dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]	(-)-secoisolariciresinol dehydrogenase activity [GO:0102911]; nucleotide binding [GO:0000166]
d1keta__d5uate1__1		Metazoa	Firmicutes	Chordata	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	dTDP-glucose 4,6-dehydratase activity [GO:0008460]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1ketb__d3ufxf1__1			Firmicutes	Deinococcus-Thermus	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; tricarboxylic acid cycle [GO:0006099]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]	tricarboxylic acid cycle [GO:0006099]			dTDP-glucose 4,6-dehydratase activity [GO:0008460]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]
d1kewa__d4bgea___1			Proteobacteria	Actinobacteria	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; NADH binding [GO:0070404]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; NADH binding [GO:0070404]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d1kewa__d4kuec1__1			Proteobacteria	Firmicutes	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; NADH binding [GO:0070404]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	fatty acid metabolic process [GO:0006631]			dTDP-glucose 4,6-dehydratase activity [GO:0008460]; NADH binding [GO:0070404]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]
d1kezc__d2dhca___1			Actinobacteria	Proteobacteria	erythronolide synthase activity [GO:0047879]; hydrolase activity, acting on ester bonds [GO:0016788]; phosphopantetheine binding [GO:0031177]; macrolide biosynthetic process [GO:0033068]	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	macrolide biosynthetic process [GO:0033068]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]			erythronolide synthase activity [GO:0047879]; hydrolase activity, acting on ester bonds [GO:0016788]; phosphopantetheine binding [GO:0031177]	haloalkane dehalogenase activity [GO:0018786]
d1kf6n1_d1h7wb1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d1kf6n2_d3p1me1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]
d1kf9e2_d2edda1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth hormone receptor complex [GO:0070195]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; growth hormone receptor activity [GO:0004903]; identical protein binding [GO:0042802]; peptide hormone binding [GO:0017046]; proline-rich region binding [GO:0070064]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; activation of Janus kinase activity [GO:0042976]; activation of MAPK activity [GO:0000187]; cellular response to hormone stimulus [GO:0032870]; endocytosis [GO:0006897]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; hormone metabolic process [GO:0042445]; insulin-like growth factor receptor signaling pathway [GO:0048009]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; receptor internalization [GO:0031623]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of multicellular organism growth [GO:0040014]; response to cycloheximide [GO:0046898]; response to estradiol [GO:0032355]; taurine metabolic process [GO:0019530]	axon [GO:0030424]; cytosol [GO:0005829]; integral component of postsynaptic density membrane [GO:0099061]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; netrin receptor activity [GO:0005042]; transmembrane signaling receptor activity [GO:0004888]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dorsal/ventral axon guidance [GO:0033563]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of netrin-activated signaling pathway [GO:1902842]; negative regulation of neuron projection development [GO:0010977]; neuron migration [GO:0001764]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of neuron death [GO:1901214]; spinal cord ventral commissure morphogenesis [GO:0021965]	activation of Janus kinase activity [GO:0042976]; activation of MAPK activity [GO:0000187]; cellular response to hormone stimulus [GO:0032870]; endocytosis [GO:0006897]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; hormone metabolic process [GO:0042445]; insulin-like growth factor receptor signaling pathway [GO:0048009]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; receptor internalization [GO:0031623]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of multicellular organism growth [GO:0040014]; response to cycloheximide [GO:0046898]; response to estradiol [GO:0032355]; taurine metabolic process [GO:0019530]	anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dorsal/ventral axon guidance [GO:0033563]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of netrin-activated signaling pathway [GO:1902842]; negative regulation of neuron projection development [GO:0010977]; neuron migration [GO:0001764]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of neuron death [GO:1901214]; spinal cord ventral commissure morphogenesis [GO:0021965]	cell surface [GO:0009986]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth hormone receptor complex [GO:0070195]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	axon [GO:0030424]; cytosol [GO:0005829]; integral component of postsynaptic density membrane [GO:0099061]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; growth hormone receptor activity [GO:0004903]; identical protein binding [GO:0042802]; peptide hormone binding [GO:0017046]; proline-rich region binding [GO:0070064]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]	netrin receptor activity [GO:0005042]; transmembrane signaling receptor activity [GO:0004888]
d1kfah1_d3kaab___1		Metazoa		Chordata		cell junction [GO:0030054]; cell surface [GO:0009986]; early endosome [GO:0005769]; extracellular region [GO:0005576]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; mediator complex [GO:0016592]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; adaptive immune response [GO:0002250]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage activation involved in immune response [GO:0002281]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte colony-stimulating factor production [GO:0071656]; negative regulation of immune response to tumor cell [GO:0002838]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of interleukin-3 production [GO:0032712]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 1 type immune response [GO:0002826]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type I interferon production [GO:0032480]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of macrophage activation [GO:0043032]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of tolerance induction dependent upon immune response [GO:0002652]; regulation of transcription by RNA polymerase II [GO:0006357]; toll-like receptor 3 signaling pathway [GO:0034138]; toll-like receptor 7 signaling pathway [GO:0034154]; toll-like receptor 9 signaling pathway [GO:0034162]		adaptive immune response [GO:0002250]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage activation involved in immune response [GO:0002281]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte colony-stimulating factor production [GO:0071656]; negative regulation of immune response to tumor cell [GO:0002838]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of interleukin-3 production [GO:0032712]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 1 type immune response [GO:0002826]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type I interferon production [GO:0032480]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of macrophage activation [GO:0043032]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of tolerance induction dependent upon immune response [GO:0002652]; regulation of transcription by RNA polymerase II [GO:0006357]; toll-like receptor 3 signaling pathway [GO:0034138]; toll-like receptor 7 signaling pathway [GO:0034154]; toll-like receptor 9 signaling pathway [GO:0034162]		cell junction [GO:0030054]; cell surface [GO:0009986]; early endosome [GO:0005769]; extracellular region [GO:0005576]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; mediator complex [GO:0016592]; plasma membrane [GO:0005886]		metal ion binding [GO:0046872]
d1kfal1_d1wcbh1__1												
d1kfam2_d2hwzl2__1												
d1kffc__d4z27b___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]
d1kffd__d2rtqb___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1kfga1_d1fp3b___1		Metazoa	Firmicutes	Chordata	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	N-acylglucosamine 2-epimerase activity [GO:0050121]; peptidase inhibitor activity [GO:0030414]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]	cellulose catabolic process [GO:0030245]	N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	N-acylglucosamine 2-epimerase activity [GO:0050121]; peptidase inhibitor activity [GO:0030414]
d1kfga2_d2ylka1__1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d1kfgb2_d3ghpb___1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1kfib1_d5f9ca3__1		Metazoa	Ciliophora	Chordata	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1kfib2_d1jdyb2__1		Metazoa	Ciliophora	Chordata	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	glucose metabolic process [GO:0006006]	cytosol [GO:0005829]	sarcoplasmic reticulum [GO:0016529]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1kfib4_d1c47b4__1		Metazoa	Ciliophora	Chordata	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	glucose metabolic process [GO:0006006]	cytosol [GO:0005829]	sarcoplasmic reticulum [GO:0016529]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1kfjb__d1j0bu___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]	tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]
d1kfqa1_d5tr2a3__1		Metazoa	Ciliophora	Chordata	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1kfqa2_d5epca2__1		Metazoa	Ciliophora	Chordata	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1kfqb1_d5epcb3__1		Metazoa	Ciliophora	Chordata	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1kfra__d1ycba___1	Metazoa	Metazoa	Platyhelminthes	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1kful1_d1alva___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; proteolysis [GO:0006508]	cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	proteolysis [GO:0006508]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d1kful3_d1au2a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d1kfva1_d1z5ca1__1			Firmicutes	Crenarchaeota	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]			class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]
d1kfya1_d2wdqi3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d1kfym3_d1m64a3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	outer membrane-bounded periplasmic space [GO:0030288]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]
d1kfyn2_d2wqyo1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d1kg0a1_d1igtd2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1kg0a1_d3ogoe___1	Metazoa	Metazoa	Chordata	Cnidaria	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	
d1kg0b1_d1nd0c2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	metal ion binding [GO:0046872]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	metal ion binding [GO:0046872]
d1kg0b1_d1wtla___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]
d1kg2a__d3d4vb1__1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1kg3a__d1muda___1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]			4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]
d1kg4a__d1vrla1__1			Proteobacteria	Firmicutes	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]			4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]	4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]
d1kg5a__d1rrsa1__1			Proteobacteria	Firmicutes	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]			4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]	4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]
d1kgce1_d3v6fb2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kgce1_d4u05a___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kgce2_d4ww1b2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kgic__d3imrb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1kgja__d3q1ec___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1kgjb__d1bm7a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1kgjc__d2h6uf___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1kgla__d1znha___1	Metazoa	Metazoa	Chordata	Chordata	cell body [GO:0044297]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; lipid homeostasis [GO:0055088]; regulation of granulocyte differentiation [GO:0030852]; response to vitamin A [GO:0033189]; retinoic acid biosynthetic process [GO:0002138]; retinol metabolic process [GO:0042572]; vitamin A metabolic process [GO:0006776]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	lipid homeostasis [GO:0055088]; regulation of granulocyte differentiation [GO:0030852]; response to vitamin A [GO:0033189]; retinoic acid biosynthetic process [GO:0002138]; retinol metabolic process [GO:0042572]; vitamin A metabolic process [GO:0006776]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cell body [GO:0044297]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinol binding [GO:0019841]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]
d1kgla__d3p6fa1__1	Metazoa	Metazoa	Chordata	Chordata	cell body [GO:0044297]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; lipid homeostasis [GO:0055088]; regulation of granulocyte differentiation [GO:0030852]; response to vitamin A [GO:0033189]; retinoic acid biosynthetic process [GO:0002138]; retinol metabolic process [GO:0042572]; vitamin A metabolic process [GO:0006776]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	lipid homeostasis [GO:0055088]; regulation of granulocyte differentiation [GO:0030852]; response to vitamin A [GO:0033189]; retinoic acid biosynthetic process [GO:0002138]; retinol metabolic process [GO:0042572]; vitamin A metabolic process [GO:0006776]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cell body [GO:0044297]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinol binding [GO:0019841]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1kgnb__d1bcfg___1			Actinobacteria	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1kgnb__d3rmkd___1			Actinobacteria	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	toluene catabolic process [GO:0042203]	ribonucleoside-diphosphate reductase complex [GO:0005971]		metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1kgnc__d2iy4i___1			Actinobacteria	Firmicutes	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1kgoc__d1nfvb___1			Actinobacteria	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1kgoc__d1xvec___1			Actinobacteria	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	ribonucleoside-diphosphate reductase complex [GO:0005971]		metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1kgpa__d1xved___1			Actinobacteria	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	ribonucleoside-diphosphate reductase complex [GO:0005971]		metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1kgpa__d2v15l___1			Actinobacteria	Firmicutes	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d1kgpb__d1mxrb___1			Actinobacteria	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1kgpc__d5i4ja___1			Actinobacteria	Cyanobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1kgpd__d2xkqi___1			Actinobacteria	Firmicutes	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d1kgua1_d3hg5b2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d1kgxa1_d1q4nx1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d1kgxa2_d1jf6b3__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1kgxa2_d3f5lb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d1kgyb__d1sddb3__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; copper ion binding [GO:0005507]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]	blood circulation [GO:0008015]; blood coagulation [GO:0007596]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]	extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	copper ion binding [GO:0005507]
d1kgyh__d2jl3b1__1	Metazoa		Chordata		axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]		angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]		axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]		amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	
d1kgza1_d4x46b1__1			Proteobacteria	Proteobacteria	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]	tryptophan biosynthetic process [GO:0000162]	pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]		cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1kh1d1_d1o96a___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	arginine biosynthetic process [GO:0006526]		cytoplasm [GO:0005737]		argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]
d1kh2c1_d1o96f1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	arginine biosynthetic process [GO:0006526]		cytoplasm [GO:0005737]		argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]
d1kh4a__d3dyca___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1kh5b__d1shna1__1		Metazoa	Proteobacteria	Arthropoda	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	alkaline phosphatase activity [GO:0004035]; metal ion binding [GO:0046872]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; metal ion binding [GO:0046872]
d1kh7b__d1elxb___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1khba2_d1yvyb1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	gluconeogenesis [GO:0006094]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]
d1khha__d4pghb2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; nucleus [GO:0005634]; guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]	acetylserotonin O-methyltransferase activity [GO:0017096]; caffeate O-methyltransferase activity [GO:0047763]; luteolin O-methyltransferase activity [GO:0030744]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; aromatic compound biosynthetic process [GO:0019438]; flavonol biosynthetic process [GO:0051555]; lignin biosynthetic process [GO:0009809]; melatonin biosynthetic process [GO:0030187]	creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]	aromatic compound biosynthetic process [GO:0019438]; flavonol biosynthetic process [GO:0051555]; lignin biosynthetic process [GO:0009809]; melatonin biosynthetic process [GO:0030187]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	acetylserotonin O-methyltransferase activity [GO:0017096]; caffeate O-methyltransferase activity [GO:0047763]; luteolin O-methyltransferase activity [GO:0030744]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d1khhb__d1zx0b___1	Metazoa		Chordata		cytoplasm [GO:0005737]; nucleus [GO:0005634]; guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]		creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]		cytoplasm [GO:0005737]; nucleus [GO:0005634]		guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	
d1khhb__d4pyma___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d1khia2_d1ph3a1__1	Fungi		Ascomycota	Ciliophora	peroxisome [GO:0005777]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; translational frameshifting [GO:0006452]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; translational frameshifting [GO:0006452]	telomere capping [GO:0016233]	peroxisome [GO:0005777]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1khka__d1k7hb1__1		Metazoa	Proteobacteria	Arthropoda	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	alkaline phosphatase activity [GO:0004035]; metal ion binding [GO:0046872]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; metal ion binding [GO:0046872]
d1khkb__d3szza___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]
d1khoa2_d1qmda2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	hemolysis in other organism [GO:0044179]	hemolysis in other organism [GO:0044179]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1khqa__d1csb.2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]		cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]	cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]
d1khrb__d4n6aa___1		Viridiplantae	Firmicutes	Streptophyta	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]	response to antibiotic [GO:0046677]	cysteine biosynthetic process from serine [GO:0006535]		cytosol [GO:0005829]	transferase activity, transferring acyl groups [GO:0016746]	serine O-acetyltransferase activity [GO:0009001]
d1khrc__d1hv9b1__1			Firmicutes	Proteobacteria	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	response to antibiotic [GO:0046677]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytosol [GO:0005829]	transferase activity, transferring acyl groups [GO:0016746]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d1khrf__d4h7oa___1			Firmicutes	Proteobacteria	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]	response to antibiotic [GO:0046677]	cysteine biosynthetic process from serine [GO:0006535]		cytosol [GO:0005829]	transferase activity, transferring acyl groups [GO:0016746]	serine O-acetyltransferase activity [GO:0009001]
d1khub__d1fhqa___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; nuclear chromatin [GO:0000790]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]; co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [GO:0030618]; BMP signaling pathway [GO:0030509]; embryonic pattern specification [GO:0009880]; positive regulation of gene expression [GO:0010628]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; primary miRNA processing [GO:0031053]; protein deubiquitination [GO:0016579]; signal transduction [GO:0007165]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	BMP signaling pathway [GO:0030509]; embryonic pattern specification [GO:0009880]; positive regulation of gene expression [GO:0010628]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; primary miRNA processing [GO:0031053]; protein deubiquitination [GO:0016579]; signal transduction [GO:0007165]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; nuclear chromatin [GO:0000790]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [GO:0030618]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]
d1khuc__d5jerg___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; nuclear chromatin [GO:0000790]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]; co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [GO:0030618]; BMP signaling pathway [GO:0030509]; embryonic pattern specification [GO:0009880]; positive regulation of gene expression [GO:0010628]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; primary miRNA processing [GO:0031053]; protein deubiquitination [GO:0016579]; signal transduction [GO:0007165]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	BMP signaling pathway [GO:0030509]; embryonic pattern specification [GO:0009880]; positive regulation of gene expression [GO:0010628]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; primary miRNA processing [GO:0031053]; protein deubiquitination [GO:0016579]; signal transduction [GO:0007165]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; nuclear chromatin [GO:0000790]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [GO:0030618]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]
d1khzb__d3shdg___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ADP-ribose diphosphatase activity [GO:0047631]; ADP-sugar diphosphatase activity [GO:0019144]; magnesium ion binding [GO:0000287]; nucleoside phosphate metabolic process [GO:0006753]; response to heat [GO:0009408]; ribose phosphate metabolic process [GO:0019693]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]	nucleoside phosphate metabolic process [GO:0006753]; response to heat [GO:0009408]; ribose phosphate metabolic process [GO:0019693]		cytosol [GO:0005829]		ADP-ribose diphosphatase activity [GO:0047631]; ADP-sugar diphosphatase activity [GO:0019144]; magnesium ion binding [GO:0000287]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]
d1ki1a__d3adka___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	cytoplasm [GO:0005737]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d1kiaa__d4qvkb___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	O-methyltransferase activity [GO:0008171]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]		cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]		folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	O-methyltransferase activity [GO:0008171]
d1kiac__d3hcbb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d1kiad__d4mhta___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	DNA restriction-modification system [GO:0009307]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]		folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d1kibc__d3l74q1__1		Metazoa	Cyanobacteria	Chordata	thylakoid lumen [GO:0031977]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	photosynthesis [GO:0015979]		thylakoid lumen [GO:0031977]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1kibh__d5dfsa___1		Metazoa	Cyanobacteria	Chordata	thylakoid lumen [GO:0031977]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]	photosynthesis [GO:0015979]	apoptotic process [GO:0006915]	thylakoid lumen [GO:0031977]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1kifa2_d1el7a2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	cytoplasm [GO:0005737]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	sarcosine oxidase activity [GO:0008115]
d1kifa2_d1s2qa2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1kifd2_d1ojdg2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1kiff2_d1h81a2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]
d1kiff2_d1l9fb4__1	Metazoa		Chordata		cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]		D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]		cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]		D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]	
d1kigh__d3keeb___1	Metazoa		Arthropoda		serine-type endopeptidase inhibitor activity [GO:0004867]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	serine-type endopeptidase inhibitor activity [GO:0004867]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1kija1_d1p42a2__1			Deinococcus-Thermus	Aquificae	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]	lipid A biosynthetic process [GO:0009245]	chromosome [GO:0005694]; cytoplasm [GO:0005737]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d1kija2_d4prxa1__1			Deinococcus-Thermus	Proteobacteria	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; DNA-dependent ATPase activity [GO:0008094]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d1kijb1_d4qnkc2__1		Viridiplantae	Deinococcus-Thermus	Streptophyta	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]	histidine biosynthetic process [GO:0000105]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	chloroplast [GO:0009507]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; metal ion binding [GO:0046872]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d1kipb1_d2j8ub2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1kiqc__d190la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1kira__d1fdlh1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1kirb__d2oqjk1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1kita1_d1i3ha___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]; ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1kita1_d6eksa3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]; ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]; ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]	ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]	ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]
d1kiub1_d4lova___1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]	mannose binding [GO:0005537]	mannose binding [GO:0005537]
d1kiub1_d4z3ha1__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1kiub2_d1kiud1__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]	mannose binding [GO:0005537]	mannose binding [GO:0005537]
d1kiuc1_d2bvub___1		Metazoa	Proteobacteria	Nematoda (roundworms)	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		host cell membrane [GO:0033644]; pilus [GO:0009289]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]	mannose binding [GO:0005537]	
d1kiud1_d1oioa___1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]; carbohydrate binding [GO:0030246]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	host cell membrane [GO:0033644]; pilus [GO:0009289]	pilus [GO:0009289]	mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]
d1kiuh2_d5ab1b___1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]	mannose binding [GO:0005537]	mannose binding [GO:0005537]
d1kiuj1_d5l4xb___1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]	mannose binding [GO:0005537]	mannose binding [GO:0005537]
d1kiul1_d4xobg1__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]	mannose binding [GO:0005537]	mannose binding [GO:0005537]
d1kiun1_d4xoae2__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]	mannose binding [GO:0005537]	mannose binding [GO:0005537]
d1kiup1_d1oiob___1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]; carbohydrate binding [GO:0030246]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	host cell membrane [GO:0033644]; pilus [GO:0009289]	pilus [GO:0009289]	mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]
d1kiup1_d1qunj1__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]	mannose binding [GO:0005537]	mannose binding [GO:0005537]
d1kixa2_d1lylc1__1			Ciliophora	Proteobacteria	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	telomere capping [GO:0016233]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	cytosol [GO:0005829]; membrane [GO:0016020]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]
d1kiya__d2aeka___1	Fungi	Fungi	Ascomycota	Ascomycota	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]			metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]
d1kiza__d2ps6a___1	Fungi	Fungi	Ascomycota	Ascomycota	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]			metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]
d1kj1a__d5t20l___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d1kj1p__d1bwua___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d1kj1p__d5t1xb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d1kj1q__d1npla___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d1kj1q__d5t20n___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d1kj2b__d3zkxc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	aspartic-type endopeptidase activity [GO:0004190]
d1kj2d__d3v7ma1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1kj2h1_d1knod1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1kj2l__d4np4l2__1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell plasma membrane [GO:0020002]; cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]
d1kj3h1_d3ngbk1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	structural molecule activity [GO:0005198]
d1kj3i1_d3jwdl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1kj3l__d3hi1a1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	structural molecule activity [GO:0005198]
d1kj3l__d3nidl2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1kj4b__d1dazc___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1kj4c__d4djwb___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d1kj7a__d2q11a___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d1kj7b__d5p36a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1kj8a1_d3mjfa3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytosol [GO:0005829]		acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d1kj8a2_d2w6qb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1kj8a2_d5bpfc1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]	cytosol [GO:0005829]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1kj8b2_d2yw2a1__1			Proteobacteria	Aquificae	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytosol [GO:0005829]		acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d1kj9b1_d4mv8a3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytosol [GO:0005829]		acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1kj9b2_d1iowa1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]	cytosol [GO:0005829]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1kjfb__d4cpub___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1kjia2_d4tv8f1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	'de novo' IMP biosynthetic process [GO:0006189]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1kjib2_d5bpfd1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]	cytosol [GO:0005829]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1kjma1_d1nj9l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; MHC class I protein complex [GO:0042612]; plasma membrane [GO:0005886]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; MHC class I protein complex [GO:0042612]; plasma membrane [GO:0005886]			
d1kjmb__d1u8nb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; MHC class I protein complex [GO:0042612]; plasma membrane [GO:0005886]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; MHC class I protein complex [GO:0042612]; plasma membrane [GO:0005886]			
d1kjmb__d4xpbl2__1	Metazoa	Metazoa	Chordata	Arthropoda	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; MHC class I protein complex [GO:0042612]; plasma membrane [GO:0005886]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]; adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; MHC class I protein complex [GO:0042612]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; neuronal cell body membrane [GO:0032809]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]		cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]
d1kjoa__d6tlia___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1kjpa__d1asta___1		Metazoa	Firmicutes	Arthropoda	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cortical granule [GO:0060473]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; aspartic-type peptidase activity [GO:0070001]; glutamic-type peptidase activity [GO:0070002]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]; cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]		cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]	extracellular region [GO:0005576]	cortical granule [GO:0060473]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	aspartic-type peptidase activity [GO:0070001]; glutamic-type peptidase activity [GO:0070002]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]
d1kjqa1_d2w71c3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1kjqa2_d5lp6f1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	'de novo' IMP biosynthetic process [GO:0006189]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1kjra__d5gm5d___1	Metazoa	Fungi	Chordata	Ascomycota	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	cellulose catabolic process [GO:0030245]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]	cellulase activity [GO:0008810]
d1kjua3_d1u7qa___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium ion-transporting ATPase complex [GO:0031004]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; potassium transmembrane transporter activity, phosphorylative mechanism [GO:0008556]; cation transmembrane transport [GO:0098655]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]	calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	cation transmembrane transport [GO:0098655]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium ion-transporting ATPase complex [GO:0031004]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; potassium transmembrane transporter activity, phosphorylative mechanism [GO:0008556]
d1kjva2_d3bzfa2__1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; proteasome complex [GO:0000502]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; cellular response to hypoxia [GO:0071456]; negative regulation of store-operated calcium channel activity [GO:1901340]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of protein ubiquitination [GO:0031398]; regulation of macroautophagy [GO:0016241]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; regulation of protein ubiquitination [GO:0031396]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; cellular response to hypoxia [GO:0071456]; negative regulation of store-operated calcium channel activity [GO:1901340]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of protein ubiquitination [GO:0031398]; regulation of macroautophagy [GO:0016241]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; regulation of protein ubiquitination [GO:0031396]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	aggresome [GO:0016235]; autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; proteasome complex [GO:0000502]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1kjza2_d4lbva3__1			Euryarchaeota	Deinococcus-Thermus	GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1kk4e__d1krrc___1			Firmicutes	Proteobacteria	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]; lactose biosynthetic process [GO:0005989]	response to antibiotic [GO:0046677]	lactose biosynthetic process [GO:0005989]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups [GO:0016746]	galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]
d1kk5c__d4knra2__1			Firmicutes	Proteobacteria	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	response to antibiotic [GO:0046677]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups [GO:0016746]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d1kk5f__d4m99a___1			Firmicutes	Proteobacteria	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	integral component of membrane [GO:0016021]; transferase activity [GO:0016740]	response to antibiotic [GO:0046677]			integral component of membrane [GO:0016021]	transferase activity, transferring acyl groups [GO:0016746]	transferase activity [GO:0016740]
d1kk6c__d1qq0a___1			Firmicutes	Euryarchaeota	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	response to antibiotic [GO:0046677]				transferase activity, transferring acyl groups [GO:0016746]	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]
d1kk7z__d2kbmb___1	Metazoa	Metazoa	Mollusca	Chordata	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	actin cortical patch [GO:0030479]; brush border [GO:0005903]; F-actin capping protein complex [GO:0008290]; membrane [GO:0016020]; actin filament binding [GO:0051015]; actin cytoskeleton organization [GO:0030036]; barbed-end actin filament capping [GO:0051016]		actin cytoskeleton organization [GO:0030036]; barbed-end actin filament capping [GO:0051016]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	actin cortical patch [GO:0030479]; brush border [GO:0005903]; F-actin capping protein complex [GO:0008290]; membrane [GO:0016020]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	actin filament binding [GO:0051015]
d1kkba__d2j7pa2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; 'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	signal recognition particle [GO:0048500]	adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1kkca2_d3esfa2__1	Fungi		Ascomycota		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1kkcb2_d1qnmb2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1kkcx2_d4f2nk2__1	Fungi		Ascomycota		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1kkcy2_d4f2ne2__1	Fungi		Ascomycota		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1kklh__d4xwjb___1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphorelay sensor kinase activity [GO:0000155]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; carbohydrate metabolic process [GO:0005975]; regulation of carbohydrate metabolic process [GO:0006109]	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]; enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	carbohydrate metabolic process [GO:0005975]; regulation of carbohydrate metabolic process [GO:0006109]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]		cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphorelay sensor kinase activity [GO:0000155]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]	enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]
d1kkqd__d1t79a___1	Metazoa	Metazoa	Chordata	Chordata	histone deacetylase complex [GO:0000118]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; glucocorticoid receptor binding [GO:0035259]; histone deacetylase binding [GO:0042826]; Notch binding [GO:0005112]; nuclear hormone receptor binding [GO:0035257]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]; estrous cycle [GO:0044849]; lactation [GO:0007595]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072365]; regulation of lipid metabolic process [GO:0019216]; response to estradiol [GO:0032355]; response to organonitrogen compound [GO:0010243]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; androgen binding [GO:0005497]; beta-catenin binding [GO:0008013]; DNA-binding transcription factor activity [GO:0003700]; nuclear receptor activity [GO:0004879]; sequence-specific DNA binding [GO:0043565]; steroid binding [GO:0005496]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]; androgen receptor signaling pathway [GO:0030521]; intracellular receptor signaling pathway [GO:0030522]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of integrin biosynthetic process [GO:0045720]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of protein localization to plasma membrane [GO:1903076]; transcription, DNA-templated [GO:0006351]	estrous cycle [GO:0044849]; lactation [GO:0007595]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072365]; regulation of lipid metabolic process [GO:0019216]; response to estradiol [GO:0032355]; response to organonitrogen compound [GO:0010243]	androgen receptor signaling pathway [GO:0030521]; intracellular receptor signaling pathway [GO:0030522]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of integrin biosynthetic process [GO:0045720]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of protein localization to plasma membrane [GO:1903076]; transcription, DNA-templated [GO:0006351]	histone deacetylase complex [GO:0000118]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; glucocorticoid receptor binding [GO:0035259]; histone deacetylase binding [GO:0042826]; Notch binding [GO:0005112]; nuclear hormone receptor binding [GO:0035257]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]	androgen binding [GO:0005497]; beta-catenin binding [GO:0008013]; DNA-binding transcription factor activity [GO:0003700]; nuclear receptor activity [GO:0004879]; sequence-specific DNA binding [GO:0043565]; steroid binding [GO:0005496]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]
d1kkta__d1hcuc___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]; protein glycosylation [GO:0006486]	membrane [GO:0016020]; calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]; metabolic process [GO:0008152]	protein glycosylation [GO:0006486]	metabolic process [GO:0008152]	extracellular region [GO:0005576]; membrane [GO:0016020]	membrane [GO:0016020]	calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]	calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]
d1kl1a__d5g09b___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]		cytoplasm [GO:0005737]		glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1kl2a__d1ahea___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1kl3c__d4z28b___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]
d1kl4d__d1hy2c___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1kl5c__d1swnd___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1klfb2_d4z3ia1__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1klfe2_d2uy7e2__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	outer membrane-bounded periplasmic space [GO:0030288]; cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	outer membrane-bounded periplasmic space [GO:0030288]	mannose binding [GO:0005537]	
d1klfi1_d3dpaa1__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	outer membrane-bounded periplasmic space [GO:0030288]; cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	outer membrane-bounded periplasmic space [GO:0030288]	mannose binding [GO:0005537]	
d1klfi2_d4ay0b2__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	outer membrane-bounded periplasmic space [GO:0030288]; cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	outer membrane-bounded periplasmic space [GO:0030288]	mannose binding [GO:0005537]	
d1klfl1_d5cf3a1__1			Proteobacteria	Firmicutes	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	host cell membrane [GO:0033644]; pilus [GO:0009289]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	mannose binding [GO:0005537]	
d1klta__d3lgib___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptide binding [GO:0042277]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; angiotensin maturation [GO:0002003]; basement membrane disassembly [GO:0034769]; cellular response to glucose stimulus [GO:0071333]; extracellular matrix disassembly [GO:0022617]; interleukin-1 beta biosynthetic process [GO:0050720]; midbrain development [GO:0030901]; positive regulation of angiogenesis [GO:0045766]; regulation of inflammatory response [GO:0050727]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	angiotensin maturation [GO:0002003]; basement membrane disassembly [GO:0034769]; cellular response to glucose stimulus [GO:0071333]; extracellular matrix disassembly [GO:0022617]; interleukin-1 beta biosynthetic process [GO:0050720]; midbrain development [GO:0030901]; positive regulation of angiogenesis [GO:0045766]; regulation of inflammatory response [GO:0050727]	cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]	peptide binding [GO:0042277]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1klub1_d1kj2i1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1klub1_d3nh7n2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; dorsal aorta morphogenesis [GO:0035912]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]
d1klub2_d2xfxa1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	
d1klub2_d4pjca1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1klva__d3n30a___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; synapse [GO:0045202]; beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; chemical synaptic transmission [GO:0007268]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein targeting [GO:0006605]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; chemical synaptic transmission [GO:0007268]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein targeting [GO:0006605]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; synapse [GO:0045202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1km0d__d3qezb___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1km0d__d4utub1__1			Euryarchaeota	Firmicutes	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	N-acylglucosamine-6-phosphate 2-epimerase activity [GO:0047465]; N-acylmannosamine-6-phosphate 2-epimerase activity [GO:0009385]; carbohydrate metabolic process [GO:0005975]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	N-acylglucosamine-6-phosphate 2-epimerase activity [GO:0047465]; N-acylmannosamine-6-phosphate 2-epimerase activity [GO:0009385]
d1km1a__d3fema___1		Fungi	Euryarchaeota	Ascomycota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]		glutaminase complex [GO:1903600]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d1km1b__d3n3mb1__1			Euryarchaeota	Apicomplexa	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1km1b__d4nu7d___1			Euryarchaeota		orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]				orotidine-5'-phosphate decarboxylase activity [GO:0004590]	
d1km3a__d3g1fj___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1km4a__d2flid___1			Euryarchaeota	Firmicutes	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d1km8a__d3tsrb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]	angiogenin-PRI complex [GO:0032311]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; ribonuclease inhibitor activity [GO:0008428]; regulation of angiogenesis [GO:0045765]		regulation of angiogenesis [GO:0045765]	extracellular region [GO:0005576]	angiogenin-PRI complex [GO:0032311]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	carbohydrate binding [GO:0030246]; endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]	ribonuclease inhibitor activity [GO:0008428]
d1kmga__d4rvpd___1	Metazoa	Viridiplantae	Chordata	Streptophyta	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]		chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1kmha1_d2jdia1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1kmha2_d3oeen1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1kmhb2_d2hldc1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1kmma1_d4eo4b2__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; mitochondrial threonyl-tRNA aminoacylation [GO:0070159]; threonyl-tRNA aminoacylation [GO:0006435]	histidyl-tRNA aminoacylation [GO:0006427]	mitochondrial threonyl-tRNA aminoacylation [GO:0070159]; threonyl-tRNA aminoacylation [GO:0006435]	cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]	ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]
d1kmnc1_d1kogb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	histidyl-tRNA aminoacylation [GO:0006427]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1kmqa__d2wmob___1	Metazoa	Metazoa	Chordata	Chordata	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]
d1kmta1_d4oy7f___1	Metazoa		Chordata	Actinobacteria	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; carbohydrate metabolic process [GO:0005975]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	carbohydrate metabolic process [GO:0005975]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]		GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]
d1kmva__d3kjrb1__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]
d1kn0b__d2nugb2__1	Metazoa		Chordata	Aquificae	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	cytoplasm [GO:0005737]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]; mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]	double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]
d1kn0h__d1x48a1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; eukaryotic translation initiation factor 2alpha kinase activity [GO:0004694]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; activation of MAPKK activity [GO:0000186]; cellular response to amino acid starvation [GO:0034198]; defense response to virus [GO:0051607]; endoplasmic reticulum unfolded protein response [GO:0030968]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of translation [GO:0017148]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic process [GO:0043065]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of NLRP3 inflammasome complex assembly [GO:1900225]; response to interferon-alpha [GO:0035455]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; response to vitamin E [GO:0033197]; translation [GO:0006412]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	activation of MAPKK activity [GO:0000186]; cellular response to amino acid starvation [GO:0034198]; defense response to virus [GO:0051607]; endoplasmic reticulum unfolded protein response [GO:0030968]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of translation [GO:0017148]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic process [GO:0043065]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of NLRP3 inflammasome complex assembly [GO:1900225]; response to interferon-alpha [GO:0035455]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; response to vitamin E [GO:0033197]; translation [GO:0006412]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; eukaryotic translation initiation factor 2alpha kinase activity [GO:0004694]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]
d1kn1a__d1nqpb___1		Metazoa	Rhodophyta	Chordata	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1kn1a__d2uumw___1			Rhodophyta	Cyanobacteria	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	phycobilisome [GO:0030089]		
d1kn2h2_d1za3l2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]
d1kn4h1_d1dqqc2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1kn4h2_d4xbgb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1kncc__d2gmyd___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; alkyl hydroperoxide reductase activity [GO:0008785]; disulfide oxidoreductase activity [GO:0015036]; hydroperoxide reductase activity [GO:0032843]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		alkyl hydroperoxide reductase activity [GO:0008785]; disulfide oxidoreductase activity [GO:0015036]; hydroperoxide reductase activity [GO:0032843]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1knga__d1gula2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	cytosol [GO:0005829]	disulfide oxidoreductase activity [GO:0015036]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1knia__d1f6sc___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	host cell cytoplasm [GO:0030430]	extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]
d1knma__d3ca1a2__1		Viridiplantae	Actinobacteria	Streptophyta	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	xylan catabolic process [GO:0045493]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1knoa1_d5vh4l2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1knoa2_d1zlsl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1knob1_d4oiil2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1knoc2_d1nlbh1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1knod1_d5nlua1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1knod2_d3hc3l2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1knoe1_d1jptl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1knoe1_d5cs7a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1knpa1_d3cira1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; flavin adenine dinucleotide binding [GO:0050660]; L-aspartate oxidase activity [GO:0008734]; L-aspartate:fumarate oxidoreductase activity [GO:0044318]; 'de novo' NAD biosynthetic process from aspartate [GO:0034628]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	'de novo' NAD biosynthetic process from aspartate [GO:0034628]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	flavin adenine dinucleotide binding [GO:0050660]; L-aspartate:fumarate oxidoreductase activity [GO:0044318]; L-aspartate oxidase activity [GO:0008734]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1knqb__d6amba1__1		Metazoa	Proteobacteria	Chordata	ATP binding [GO:0005524]; gluconokinase activity [GO:0046316]; D-gluconate catabolic process [GO:0046177]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	D-gluconate catabolic process [GO:0046177]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; gluconokinase activity [GO:0046316]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1knva__d4m5ra1__1			Firmicutes		endonuclease activity [GO:0004519]						endonuclease activity [GO:0004519]	
d1knya1_d1ufbd___1			Firmicutes	Deinococcus-Thermus	nucleotidyltransferase activity [GO:0016779]; response to antibiotic [GO:0046677]	phosphorelay signal transduction system [GO:0000160]	response to antibiotic [GO:0046677]	phosphorelay signal transduction system [GO:0000160]			nucleotidyltransferase activity [GO:0016779]	
d1ko7a1_d1knxf1__1			Firmicutes	Tenericutes	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphorelay sensor kinase activity [GO:0000155]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; carbohydrate metabolic process [GO:0005975]; regulation of carbohydrate metabolic process [GO:0006109]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphorelay sensor kinase activity [GO:0000155]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; carbohydrate metabolic process [GO:0005975]; regulation of carbohydrate metabolic process [GO:0006109]	carbohydrate metabolic process [GO:0005975]; regulation of carbohydrate metabolic process [GO:0006109]	carbohydrate metabolic process [GO:0005975]; regulation of carbohydrate metabolic process [GO:0006109]			ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphorelay sensor kinase activity [GO:0000155]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphorelay sensor kinase activity [GO:0000155]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]
d1ko7b1_d1knxc1__1			Firmicutes	Tenericutes	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphorelay sensor kinase activity [GO:0000155]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; carbohydrate metabolic process [GO:0005975]; regulation of carbohydrate metabolic process [GO:0006109]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphorelay sensor kinase activity [GO:0000155]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; carbohydrate metabolic process [GO:0005975]; regulation of carbohydrate metabolic process [GO:0006109]	carbohydrate metabolic process [GO:0005975]; regulation of carbohydrate metabolic process [GO:0006109]	carbohydrate metabolic process [GO:0005975]; regulation of carbohydrate metabolic process [GO:0006109]			ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphorelay sensor kinase activity [GO:0000155]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphorelay sensor kinase activity [GO:0000155]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]
d1ko9a1_d1n39a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]
d1ko9a1_d2ofka___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]
d1ko9a2_d1jfic2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714]; negative regulation of transcription by RNA polymerase II [GO:0000122]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	negative regulation of transcription by RNA polymerase II [GO:0000122]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleus [GO:0005634]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714]
d1koba__d3db6a___1	Metazoa	Metazoa	Mollusca	Chordata	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; spindle pole [GO:0000922]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; mitotic cell cycle [GO:0000278]; regulation of cytokinesis [GO:0032465]		mitotic cell cycle [GO:0000278]; regulation of cytokinesis [GO:0032465]		centrosome [GO:0005813]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; spindle pole [GO:0000922]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]
d1koea__d1bnlb___1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; response to drug [GO:0042493]; response to hydrostatic pressure [GO:0051599]; visual perception [GO:0007601]	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; response to drug [GO:0042493]; response to hydrostatic pressure [GO:0051599]; visual perception [GO:0007601]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1kofa__d2j0qb2__1		Metazoa	Proteobacteria	Chordata	ATP binding [GO:0005524]; gluconokinase activity [GO:0046316]; D-gluconate catabolic process [GO:0046177]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]	D-gluconate catabolic process [GO:0046177]	mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]		catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]	ATP binding [GO:0005524]; gluconokinase activity [GO:0046316]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1koga1_d4p3nd2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]
d1kogb2_d4ycub2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]; activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]
d1kogc2_d1wqwb2__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d1kogd1_d4ttvc2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]
d1koge2_d1wnla2__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d1kogh1_d4p3na2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]
d1koha1_d1otna___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d1kohd__d3h3ba1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]
d1koja__d2cxpa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d1kolb2_d3btoc2__1		Metazoa	Proteobacteria	Chordata	formaldehyde dehydrogenase activity [GO:0018467]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	formaldehyde dehydrogenase activity [GO:0018467]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1kooa1_d1moxb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d1koob__d3rw7d___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1kooc1_d1koha1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1kooc2_d1koha2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1kood__d1a9nc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	catalytic step 2 spliceosome [GO:0071013]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small nuclear ribonucleoprotein complex [GO:0030532]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; RNA binding [GO:0003723]; U2 snRNA binding [GO:0030620]; interleukin-12-mediated signaling pathway [GO:0035722]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	interleukin-12-mediated signaling pathway [GO:0035722]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	catalytic step 2 spliceosome [GO:0071013]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small nuclear ribonucleoprotein complex [GO:0030532]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	RNA binding [GO:0003723]; U2 snRNA binding [GO:0030620]
d1kp3a1_d2e21c1__1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; arginine biosynthetic process [GO:0006526]; argininosuccinate metabolic process [GO:0000053]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; tRNA modification [GO:0006400]	arginine biosynthetic process [GO:0006526]; argininosuccinate metabolic process [GO:0000053]; urea cycle [GO:0000050]	tRNA modification [GO:0006400]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]
d1kp8e2_d3m6ca___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	bacterial nucleoid [GO:0043590]; cell surface [GO:0009986]; cell wall [GO:0005618]; GroEL-GroES complex [GO:1990220]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; single-stranded DNA binding [GO:0003697]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; DNA protection [GO:0042262]; nucleoid organization [GO:0090143]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein refolding [GO:0042026]; response to heat [GO:0009408]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; DNA protection [GO:0042262]; nucleoid organization [GO:0090143]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein refolding [GO:0042026]; response to heat [GO:0009408]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	bacterial nucleoid [GO:0043590]; cell surface [GO:0009986]; cell wall [GO:0005618]; GroEL-GroES complex [GO:1990220]; plasma membrane [GO:0005886]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; single-stranded DNA binding [GO:0003697]; unfolded protein binding [GO:0051082]
d1kp8f2_d1grlg2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]
d1kp8g2_d1a6ea2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1kp8i2_d1wf4g2__1			Proteobacteria		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]		'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	
d1kp8l2_d1q3sh2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1kp9b__d2fk8a___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]; lipid biosynthetic process [GO:0008610]; mycolic acid biosynthetic process [GO:0071768]; S-adenosylmethionine metabolic process [GO:0046500]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; methyltransferase activity [GO:0008168]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; mycolic acid biosynthetic process [GO:0071768]	lipid biosynthetic process [GO:0008610]; mycolic acid biosynthetic process [GO:0071768]; S-adenosylmethionine metabolic process [GO:0046500]	mycolic acid biosynthetic process [GO:0071768]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]	methyltransferase activity [GO:0008168]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d1kpab__d2q4ha2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]
d1kpca__d1gupa2__1	Metazoa		Chordata	Proteobacteria	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; galactose catabolic process via UDP-galactose [GO:0033499]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	galactose catabolic process via UDP-galactose [GO:0033499]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]	ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]
d1kphb__d2pxab___1			Actinobacteria		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]; lipid biosynthetic process [GO:0008610]; mycolic acid biosynthetic process [GO:0071768]; S-adenosylmethionine metabolic process [GO:0046500]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	lipid biosynthetic process [GO:0008610]; mycolic acid biosynthetic process [GO:0071768]; S-adenosylmethionine metabolic process [GO:0046500]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1kphc__d3ha5a___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]; lipid biosynthetic process [GO:0008610]; mycolic acid biosynthetic process [GO:0071768]; S-adenosylmethionine metabolic process [GO:0046500]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; methyltransferase activity [GO:0008168]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; mycolic acid biosynthetic process [GO:0071768]	lipid biosynthetic process [GO:0008610]; mycolic acid biosynthetic process [GO:0071768]; S-adenosylmethionine metabolic process [GO:0046500]	mycolic acid biosynthetic process [GO:0071768]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]	methyltransferase activity [GO:0008168]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d1kphd__d4bp1c___1			Actinobacteria	Apicomplexa	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]; lipid biosynthetic process [GO:0008610]; mycolic acid biosynthetic process [GO:0071768]; S-adenosylmethionine metabolic process [GO:0046500]	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	lipid biosynthetic process [GO:0008610]; mycolic acid biosynthetic process [GO:0071768]; S-adenosylmethionine metabolic process [GO:0046500]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]	spermidine synthase activity [GO:0004766]
d1kpia__d1kphd___1			Actinobacteria	Actinobacteria	cytosol [GO:0005829]; plasma membrane [GO:0005886]; cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]; Actinobacterium-type cell wall biogenesis [GO:0071766]; lipid biosynthetic process [GO:0008610]; modulation by symbiont of host innate immune response [GO:0052167]; mycolate cell wall layer assembly [GO:0071769]; mycolic acid biosynthetic process [GO:0071768]; response to hypoxia [GO:0001666]; S-adenosylmethionine metabolic process [GO:0046500]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]; lipid biosynthetic process [GO:0008610]; mycolic acid biosynthetic process [GO:0071768]; S-adenosylmethionine metabolic process [GO:0046500]	Actinobacterium-type cell wall biogenesis [GO:0071766]; lipid biosynthetic process [GO:0008610]; modulation by symbiont of host innate immune response [GO:0052167]; mycolate cell wall layer assembly [GO:0071769]; mycolic acid biosynthetic process [GO:0071768]; response to hypoxia [GO:0001666]; S-adenosylmethionine metabolic process [GO:0046500]	lipid biosynthetic process [GO:0008610]; mycolic acid biosynthetic process [GO:0071768]; S-adenosylmethionine metabolic process [GO:0046500]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]	cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]
d1kpma__d2b03a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]; bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	extracellular region [GO:0005576]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]
d1kpov2_d1q3sc2__1				Euryarchaeota		ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]		protein folding [GO:0006457]				ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1kpoz2_d1sjpb2__1				Actinobacteria		capsule [GO:0042603]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; GroEL-GroES complex [GO:1990220]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; adhesion of symbiont to host [GO:0044406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]		'de novo' protein folding [GO:0006458]; adhesion of symbiont to host [GO:0044406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]		capsule [GO:0042603]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; GroEL-GroES complex [GO:1990220]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1kpra1_d5ijvl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1kprc1_d1igyc2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1kprd1_d4f7ea2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1kpua1_d3dx9d2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1kpva1_d4zfgl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]
d1kpvb__d4depb2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]
d1kq1h__d3qhsd___1			Firmicutes	Proteobacteria	RNA binding [GO:0003723]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; bent DNA binding [GO:0003681]; RNA binding [GO:0003723]; negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	regulation of transcription, DNA-templated [GO:0006355]	negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]		cytosol [GO:0005829]	RNA binding [GO:0003723]	bent DNA binding [GO:0003681]; RNA binding [GO:0003723]
d1kq5a__d1f5ib___1	Fungi		Ascomycota		actin cortical patch [GO:0030479]; cortical actin cytoskeleton [GO:0030864]; mating projection tip [GO:0043332]; actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]; identical protein binding [GO:0042802]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; positive regulation of actin filament depolymerization [GO:0030836]; Ras protein signal transduction [GO:0007265]		actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; actin polymerization or depolymerization [GO:0008154]; cell morphogenesis [GO:0000902]; establishment or maintenance of cell polarity [GO:0007163]; positive regulation of actin filament depolymerization [GO:0030836]; Ras protein signal transduction [GO:0007265]		actin cortical patch [GO:0030479]; cortical actin cytoskeleton [GO:0030864]; mating projection tip [GO:0043332]		actin binding [GO:0003779]; adenylate cyclase binding [GO:0008179]; identical protein binding [GO:0042802]	
d1kq8a__d3co7c___1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein phosphatase 2A binding [GO:0051721]; sequence-specific DNA binding [GO:0043565]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; blood vessel development [GO:0001568]; cellular glucose homeostasis [GO:0001678]; cellular response to cold [GO:0070417]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to nitric oxide [GO:0071732]; cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; cytokine-mediated signaling pathway [GO:0019221]; enamel mineralization [GO:0070166]; endocrine pancreas development [GO:0031018]; energy homeostasis [GO:0097009]; fat cell differentiation [GO:0045444]; glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter [GO:0035947]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to fluoride [GO:1902617]; temperature homeostasis [GO:0001659]	anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357]	apoptotic process [GO:0006915]; autophagy [GO:0006914]; blood vessel development [GO:0001568]; cellular glucose homeostasis [GO:0001678]; cellular response to cold [GO:0070417]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to nitric oxide [GO:0071732]; cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; cytokine-mediated signaling pathway [GO:0019221]; enamel mineralization [GO:0070166]; endocrine pancreas development [GO:0031018]; energy homeostasis [GO:0097009]; fat cell differentiation [GO:0045444]; glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein acetylation [GO:0006473]; regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter [GO:0035947]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to fluoride [GO:1902617]; temperature homeostasis [GO:0001659]	nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]	beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein phosphatase 2A binding [GO:0051721]; sequence-specific DNA binding [GO:0043565]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d1kqaa__d2fkoa___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]; lactose biosynthetic process [GO:0005989]	metal ion binding [GO:0046872]	lactose biosynthetic process [GO:0005989]		cytoplasm [GO:0005737]		galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]	metal ion binding [GO:0046872]
d1kqac__d3tk8b___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]; lactose biosynthetic process [GO:0005989]	cytoplasm [GO:0005737]; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	lactose biosynthetic process [GO:0005989]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]
d1kqda__d3x21a___1			Proteobacteria	Proteobacteria	oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; membrane [GO:0016020]; 6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]; 2,4,6-trinitrotoluene catabolic process [GO:0046256]		2,4,6-trinitrotoluene catabolic process [GO:0046256]		cytosol [GO:0005829]; membrane [GO:0016020]	oxidoreductase activity [GO:0016491]	6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]
d1kqka__d2l3ma1__1			Firmicutes	Firmicutes	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; identical protein binding [GO:0042802]	copper ion binding [GO:0005507]; copper ion transport [GO:0006825]		copper ion transport [GO:0006825]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; identical protein binding [GO:0042802]	copper ion binding [GO:0005507]
d1kqka__d3k7rk___1		Fungi	Firmicutes	Ascomycota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; identical protein binding [GO:0042802]	cell [GO:0005623]; cytosol [GO:0005829]; copper chaperone activity [GO:0016531]; cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]		cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]	ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; identical protein binding [GO:0042802]	copper chaperone activity [GO:0016531]
d1kqpa__d5ahwc___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]; NAD biosynthetic process [GO:0009435]; sporulation resulting in formation of a cellular spore [GO:0030435]	nucleotide binding [GO:0000166]	NAD biosynthetic process [GO:0009435]; sporulation resulting in formation of a cellular spore [GO:0030435]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]	nucleotide binding [GO:0000166]
d1kqsb__d4acaa2__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; selenocysteine incorporation [GO:0001514]	translation [GO:0006412]	selenocysteine incorporation [GO:0001514]	ribosome [GO:0005840]	cytoplasm [GO:0005737]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1kqsi__d2qbkj1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1kqsl__d2otlm1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1kqss__d2j01t1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1kqxa__d1kt3a___1	Metazoa	Metazoa	Chordata	Chordata	lipid binding [GO:0008289]	extracellular space [GO:0005615]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]				extracellular space [GO:0005615]	lipid binding [GO:0008289]	retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]
d1kr1a__d5bywc___1	Viridiplantae		Streptophyta	Firmicutes	vacuole [GO:0005773]; chitinase activity [GO:0004568]; lysozyme activity [GO:0003796]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	vacuole [GO:0005773]		chitinase activity [GO:0004568]; lysozyme activity [GO:0003796]	cellulase activity [GO:0008810]
d1kr6a__d4dd8b___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	alpha9-beta1 integrin-ADAM8 complex [GO:0071133]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dense core granule membrane [GO:0032127]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; phagolysosome [GO:0032010]; plasma membrane [GO:0005886]; podosome [GO:0002102]; specific granule [GO:0042581]; specific granule membrane [GO:0035579]; tertiary granule [GO:0070820]; tertiary granule membrane [GO:0070821]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; protein self-association [GO:0043621]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cellular response to hypoxia [GO:0071456]; extracellular matrix disassembly [GO:0022617]; inflammatory response [GO:0006954]; leukocyte migration involved in inflammatory response [GO:0002523]; lymphocyte chemotaxis [GO:0048247]; negative regulation of neuron apoptotic process [GO:0043524]; neutrophil degranulation [GO:0043312]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell adhesion [GO:0045785]; positive regulation of eosinophil migration [GO:2000418]; positive regulation of fibronectin-dependent thymocyte migration [GO:2000415]; positive regulation of innate immune response [GO:0045089]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein processing [GO:0010954]; positive regulation of protein secretion [GO:0050714]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; regulation of cell-cell adhesion [GO:0022407]		angiogenesis [GO:0001525]; cell-cell adhesion [GO:0098609]; cell morphogenesis [GO:0000902]; cellular response to hypoxia [GO:0071456]; extracellular matrix disassembly [GO:0022617]; inflammatory response [GO:0006954]; leukocyte migration involved in inflammatory response [GO:0002523]; lymphocyte chemotaxis [GO:0048247]; negative regulation of neuron apoptotic process [GO:0043524]; neutrophil degranulation [GO:0043312]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell adhesion [GO:0045785]; positive regulation of eosinophil migration [GO:2000418]; positive regulation of fibronectin-dependent thymocyte migration [GO:2000415]; positive regulation of innate immune response [GO:0045089]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein processing [GO:0010954]; positive regulation of protein secretion [GO:0050714]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; regulation of cell-cell adhesion [GO:0022407]	extracellular region [GO:0005576]	alpha9-beta1 integrin-ADAM8 complex [GO:0071133]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dense core granule membrane [GO:0032127]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; phagolysosome [GO:0032010]; plasma membrane [GO:0005886]; podosome [GO:0002102]; specific granule [GO:0042581]; specific granule membrane [GO:0035579]; tertiary granule [GO:0070820]; tertiary granule membrane [GO:0070821]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; protein self-association [GO:0043621]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1kraa__d2fvhc___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d1krfa__d5kk7a___1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]; protein glycosylation [GO:0006486]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; extracellular vesicle [GO:1903561]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]; endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; oligosaccharide metabolic process [GO:0009311]; protein alpha-1,2-demannosylation [GO:0036508]; protein glycosylation [GO:0006486]; trimming of first mannose on A branch [GO:0036511]; trimming of second mannose on A branch [GO:0036512]; trimming of terminal mannose on B branch [GO:0036509]; trimming of terminal mannose on C branch [GO:0036510]; ubiquitin-dependent ERAD pathway [GO:0030433]	protein glycosylation [GO:0006486]	endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; oligosaccharide metabolic process [GO:0009311]; protein alpha-1,2-demannosylation [GO:0036508]; protein glycosylation [GO:0006486]; trimming of first mannose on A branch [GO:0036511]; trimming of second mannose on A branch [GO:0036512]; trimming of terminal mannose on B branch [GO:0036509]; trimming of terminal mannose on C branch [GO:0036510]; ubiquitin-dependent ERAD pathway [GO:0030433]	extracellular region [GO:0005576]; membrane [GO:0016020]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; extracellular vesicle [GO:1903561]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]	calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]
d1krha1_d4k1xb1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]; toluene catabolic process [GO:0042203]	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	toluene catabolic process [GO:0042203]			cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1krhb1_d3ozua2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]; toluene catabolic process [GO:0042203]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	toluene catabolic process [GO:0042203]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]		cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1kria__d4ym1b___1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; sialic acid binding [GO:0033691]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; receptor-mediated virion attachment to host cell [GO:0046813]; viral entry into host cell [GO:0046718]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; receptor-mediated virion attachment to host cell [GO:0046813]; viral entry into host cell [GO:0046718]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	sialic acid binding [GO:0033691]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d1krja__d4ccxa___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1krl.2_d4n6ma___1	Viridiplantae	Metazoa	Streptophyta	Chordata		cornified envelope [GO:0001533]; extracellular exosome [GO:0070062]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; anatomical structure morphogenesis [GO:0009653]; epidermis development [GO:0008544]		anatomical structure morphogenesis [GO:0009653]; epidermis development [GO:0008544]		cornified envelope [GO:0001533]; extracellular exosome [GO:0070062]		cysteine-type endopeptidase inhibitor activity [GO:0004869]
d1krra__d5depe___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]; lactose biosynthetic process [GO:0005989]	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	lactose biosynthetic process [GO:0005989]	lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]
d1kruc__d1kgqa___1			Proteobacteria		cytoplasm [GO:0005737]; galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]; lactose biosynthetic process [GO:0005989]	cytoplasm [GO:0005737]; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	lactose biosynthetic process [GO:0005989]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]
d1krva__d2qiaa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]; lactose biosynthetic process [GO:0005989]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; identical protein binding [GO:0042802]; lipid A biosynthetic process [GO:0009245]	lactose biosynthetic process [GO:0005989]	lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; identical protein binding [GO:0042802]
d1krvb__d1mr7y___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]; lactose biosynthetic process [GO:0005989]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	lactose biosynthetic process [GO:0005989]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]		galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]	transferase activity, transferring acyl groups [GO:0016746]
d1krvc__d4eqyg___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]; lactose biosynthetic process [GO:0005989]	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	lactose biosynthetic process [GO:0005989]	lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]
d1krxa__d3ltea___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphorelay response regulator activity [GO:0000156]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; nitrogen fixation [GO:0009399]; regulation of nitrogen utilization [GO:0006808]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	nitrogen fixation [GO:0009399]; regulation of nitrogen utilization [GO:0006808]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; phosphorelay response regulator activity [GO:0000156]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]
d1ks5a__d3b7ma___1	Fungi		Ascomycota	Bacteroidetes	cellulase activity [GO:0008810]; transferase activity [GO:0016740]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]; transferase activity [GO:0016740]	cellulase activity [GO:0008810]
d1ks5a__d4fqza1__1	Fungi	Metazoa	Ascomycota	Chordata	cellulase activity [GO:0008810]; transferase activity [GO:0016740]; polysaccharide catabolic process [GO:0000272]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	polysaccharide catabolic process [GO:0000272]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	cellulase activity [GO:0008810]; transferase activity [GO:0016740]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d1ks8a1_d5gy3a___1	Metazoa		Arthropoda	Proteobacteria	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1ksib3_d1d6za3__1	Viridiplantae		Streptophyta	Proteobacteria	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; oxidation-reduction process [GO:0055114]	amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]		periplasmic space [GO:0042597]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d1ksob__d1yuub___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]		cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d1ksra__d2d7qa1__1		Metazoa		Chordata	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]; actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]; actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]	actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]
d1ksub3_d1d4cc3__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	periplasmic space [GO:0042597]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; tricarboxylic acid cycle [GO:0006099]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	anaerobic respiration [GO:0009061]; tricarboxylic acid cycle [GO:0006099]	outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]	fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; succinate dehydrogenase activity [GO:0000104]
d1ksxa__d1tbda1__1					host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA replication [GO:0006260]	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]	host cell nucleus [GO:0042025]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]
d1ksxb__d1l2ma___1					host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA replication [GO:0006260]	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endodeoxyribonuclease activity, producing 5'-phosphomonoesters [GO:0016888]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleotidyltransferase activity [GO:0016779]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; viral process [GO:0016032]	DNA replication [GO:0006260]	DNA replication [GO:0006260]; viral process [GO:0016032]	host cell nucleus [GO:0042025]	host cell nucleus [GO:0042025]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endodeoxyribonuclease activity, producing 5'-phosphomonoesters [GO:0016888]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleotidyltransferase activity [GO:0016779]; structural molecule activity [GO:0005198]
d1ksxf__d2itlb___1					host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA replication [GO:0006260]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; hydrolase activity [GO:0016787]; DNA replication [GO:0006260]	DNA replication [GO:0006260]	DNA replication [GO:0006260]	host cell nucleus [GO:0042025]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; hydrolase activity [GO:0016787]
d1ksxm__d1m55b___1					host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA replication [GO:0006260]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; DNA replication [GO:0006260]; viral genome replication [GO:0019079]	DNA replication [GO:0006260]	DNA replication [GO:0006260]; viral genome replication [GO:0019079]	host cell nucleus [GO:0042025]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d1ksyb1_d5cyna___1					host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA replication [GO:0006260]	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; DNA replication [GO:0006260]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	DNA replication [GO:0006260]	DNA replication [GO:0006260]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell nucleus [GO:0042025]	host cell nucleus [GO:0042025]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1kt0a3_d2vn1a1__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein dimerization activity [GO:0046983]; chaperone-mediated protein folding [GO:0061077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	chaperone-mediated protein folding [GO:0061077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein dimerization activity [GO:0046983]
d1kt2a1_d1fl5b2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]		integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]			
d1kt2a1_d3skng1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1kt2b2_d5iueg1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1kt2d1_d5w1wn1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ktdb2_d4wo4a1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ktdc1_d4nugl1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]		integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]			
d1ktdc1_d4q74a1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ktdc2_d1zvsa2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ktga__d1r67a1__1	Metazoa		Nematoda (roundworms)	Proteobacteria	5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity [GO:0043135]; ATP binding [GO:0005524]; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]; ADP biosynthetic process [GO:0006172]; AMP biosynthetic process [GO:0006167]; apoptotic process [GO:0006915]; ATP biosynthetic process [GO:0006754]; diadenosine tetraphosphate catabolic process [GO:0015967]; ribose phosphate metabolic process [GO:0019693]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	ADP biosynthetic process [GO:0006172]; AMP biosynthetic process [GO:0006167]; apoptotic process [GO:0006915]; ATP biosynthetic process [GO:0006754]; diadenosine tetraphosphate catabolic process [GO:0015967]; ribose phosphate metabolic process [GO:0019693]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]		cytoplasm [GO:0005737]	5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity [GO:0043135]; ATP binding [GO:0005524]; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]
d1ktga__d3u53d___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity [GO:0043135]; ATP binding [GO:0005524]; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]; ADP biosynthetic process [GO:0006172]; AMP biosynthetic process [GO:0006167]; apoptotic process [GO:0006915]; ATP biosynthetic process [GO:0006754]; diadenosine tetraphosphate catabolic process [GO:0015967]; ribose phosphate metabolic process [GO:0019693]	mitochondrial matrix [GO:0005759]; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity [GO:0008803]; GTP binding [GO:0005525]; apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; nucleobase-containing compound metabolic process [GO:0006139]	ADP biosynthetic process [GO:0006172]; AMP biosynthetic process [GO:0006167]; apoptotic process [GO:0006915]; ATP biosynthetic process [GO:0006754]; diadenosine tetraphosphate catabolic process [GO:0015967]; ribose phosphate metabolic process [GO:0019693]	apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; nucleobase-containing compound metabolic process [GO:0006139]		mitochondrial matrix [GO:0005759]	5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity [GO:0043135]; ATP binding [GO:0005524]; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity [GO:0008803]; GTP binding [GO:0005525]
d1ktkb1_d1ltte___1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	toxin activity [GO:0090729]
d1ktla1_d3igaa1__1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	voltage-gated potassium channel complex [GO:0008076]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1ktlc2_d4pjfc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ktna__d3cwna___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; deoxyribose-phosphate aldolase activity [GO:0004139]; lyase activity [GO:0016829]; carbohydrate catabolic process [GO:0016052]; cellular response to DNA damage stimulus [GO:0006974]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]; nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	carbohydrate catabolic process [GO:0016052]; cellular response to DNA damage stimulus [GO:0006974]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]; nucleobase-containing small molecule interconversion [GO:0015949]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	deoxyribose-phosphate aldolase activity [GO:0004139]; lyase activity [GO:0016829]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d1ktnb__d4i7ub1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; deoxyribose-phosphate aldolase activity [GO:0004139]; lyase activity [GO:0016829]; carbohydrate catabolic process [GO:0016052]; cellular response to DNA damage stimulus [GO:0006974]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]; nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]; pyruvate metabolic process [GO:0006090]	carbohydrate catabolic process [GO:0016052]; cellular response to DNA damage stimulus [GO:0006974]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]; nucleobase-containing small molecule interconversion [GO:0015949]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]; pyruvate metabolic process [GO:0006090]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	deoxyribose-phosphate aldolase activity [GO:0004139]; lyase activity [GO:0016829]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1ktpa__d5aqdj___1			Cyanobacteria	Cyanobacteria	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	phycobilisome [GO:0030089]	phycobilisome [GO:0030089]		
d1ktrh1_d4xnxl2__1		Metazoa		Arthropoda		integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]; adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]		adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]		integral component of plasma membrane [GO:0005887]; neuronal cell body membrane [GO:0032809]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]		cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]
d1ktva3_d3df1e1__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]		translational elongation [GO:0006414]		cytoplasm [GO:0005737]		GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]	
d1ktvb4_d1zm4a5__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	translational elongation [GO:0006414]		cytoplasm [GO:0005737]		GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d1ku0b__d2v9za___1			Firmicutes	Actinobacteria	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]		response to toxic substance [GO:0009636]			metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	haloalkane dehalogenase activity [GO:0018786]
d1ku1b1_d4oiya1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; Golgi cis cisterna [GO:0000137]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; actin cytoskeleton organization [GO:0030036]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; macroautophagy [GO:0016236]; regulation of ARF protein signal transduction [GO:0032012]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; secretory granule organization [GO:0033363]	cytosol [GO:0005829]; Golgi-associated vesicle [GO:0005798]; late endosome [GO:0005770]; trans-Golgi network [GO:0005802]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; autophagosome assembly [GO:0000045]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]	actin cytoskeleton organization [GO:0030036]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; macroautophagy [GO:0016236]; regulation of ARF protein signal transduction [GO:0032012]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; secretory granule organization [GO:0033363]	autophagosome assembly [GO:0000045]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]	cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; Golgi cis cisterna [GO:0000137]	cytosol [GO:0005829]; Golgi-associated vesicle [GO:0005798]; late endosome [GO:0005770]; trans-Golgi network [GO:0005802]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]
d1ku2b2_d4g7of1__1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]; transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]	transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d1ku5a__d2cv5g___1		Metazoa	Euryarchaeota	Chordata	chromosome [GO:0005694]; cytoplasm [GO:0005737]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1ku8.1_d1j4td___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1ku8.2_d2gucb1__1	Viridiplantae		Streptophyta	Rhodophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	cell [GO:0005623]; carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]				cell [GO:0005623]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]
d1ku8.3_d1x1vb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1ku8.3_d2gtya1__1	Viridiplantae		Streptophyta	Rhodophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	cell [GO:0005623]; carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]				cell [GO:0005623]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]
d1ku8.4_d4pikb1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1kuga__d1iaga___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1kuha__d5i2zd___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1kuia__d1fjva___1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1kuj.2_d1toq.1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]
d1kuj.2_d3r51a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1kuj.4_d4piub1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1kuka__d2mlra___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1kuqa__d2uxco1__1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1kuxa__d2yndc1__1	Metazoa		Chordata	Apicomplexa	perinuclear region of cytoplasm [GO:0048471]; aralkylamine N-acetyltransferase activity [GO:0004059]; cellular response to cAMP [GO:0071320]; circadian rhythm [GO:0007623]; melatonin biosynthetic process [GO:0030187]; N-terminal protein amino acid acetylation [GO:0006474]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]	cellular response to cAMP [GO:0071320]; circadian rhythm [GO:0007623]; melatonin biosynthetic process [GO:0030187]; N-terminal protein amino acid acetylation [GO:0006474]	N-terminal protein myristoylation [GO:0006499]	perinuclear region of cytoplasm [GO:0048471]		aralkylamine N-acetyltransferase activity [GO:0004059]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d1kuya__d5f49b___1	Metazoa		Chordata		perinuclear region of cytoplasm [GO:0048471]; aralkylamine N-acetyltransferase activity [GO:0004059]; cellular response to cAMP [GO:0071320]; circadian rhythm [GO:0007623]; melatonin biosynthetic process [GO:0030187]; N-terminal protein amino acid acetylation [GO:0006474]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]	cellular response to cAMP [GO:0071320]; circadian rhythm [GO:0007623]; melatonin biosynthetic process [GO:0030187]; N-terminal protein amino acid acetylation [GO:0006474]		perinuclear region of cytoplasm [GO:0048471]		aralkylamine N-acetyltransferase activity [GO:0004059]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]
d1kv3b2_d1sgxa8__1	Metazoa		Chordata		cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]		apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]		cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	
d1kv3c3_d1f13a3__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1kv3e2_d1kv3b3__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1kv3f2_d1nuga3__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]
d1kv3f4_d1l9ma4__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]
d1kv6a__d5k38b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d1kv6b__d5lwpa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d1kv7a1_d4a2da3__1		Fungi	Proteobacteria	Basidiomycota	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1kv7a2_d3ieaa___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1kv8a__d3lhvb___1			Proteobacteria	Euryarchaeota	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1kvaa__d1jlga1__1			Proteobacteria		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1kvba__d1jl1a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1kvca__d3aa4a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1kve.1_d1kpta___1	Fungi		Ascomycota		extracellular region [GO:0005576]; toxin activity [GO:0090729]; cell death [GO:0008219]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	cell death [GO:0008219]; pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1kvja__d2gcfa___1	Metazoa		Chordata	Cyanobacteria	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]; antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper ion import [GO:0015677]	antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	copper ion import [GO:0015677]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]	ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]
d1kvka2_d2r3vc2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; peroxisome [GO:0005777]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]; mRNA binding [GO:0003729]; sequence-specific mRNA binding [GO:1990825]; cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; isoprenoid metabolic process [GO:0006720]; negative regulation of translation [GO:0017148]; regulation of cholesterol biosynthetic process [GO:0045540]; sterol metabolic process [GO:0016125]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; peroxisome [GO:0005777]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]; cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; negative regulation of inflammatory response [GO:0050728]; regulation of cholesterol biosynthetic process [GO:0045540]	cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; isoprenoid metabolic process [GO:0006720]; negative regulation of translation [GO:0017148]; regulation of cholesterol biosynthetic process [GO:0045540]; sterol metabolic process [GO:0016125]	cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; negative regulation of inflammatory response [GO:0050728]; regulation of cholesterol biosynthetic process [GO:0045540]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; peroxisome [GO:0005777]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; peroxisome [GO:0005777]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]; mRNA binding [GO:0003729]; sequence-specific mRNA binding [GO:1990825]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]
d1kvna__d4xcoa___1			Euryarchaeota	Euryarchaeota	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle, endoplasmic reticulum targeting [GO:0005786]; 7S RNA binding [GO:0008312]; SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition [GO:0006617]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition [GO:0006617]	signal recognition particle [GO:0048500]	signal recognition particle, endoplasmic reticulum targeting [GO:0005786]	7S RNA binding [GO:0008312]	7S RNA binding [GO:0008312]
d1kvoe__d1b4wa___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]; antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]	extracellular region [GO:0005576]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1kvqa__d4z3da___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]; carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; 15-hydroxyprostaglandin dehydrogenase (NADP+) activity [GO:0047021]; carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; prostaglandin-E2 9-reductase activity [GO:0050221]; cyclooxygenase pathway [GO:0019371]; drug metabolic process [GO:0017144]; epithelial cell differentiation [GO:0030855]; oxidation-reduction process [GO:0055114]; vitamin K metabolic process [GO:0042373]	carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	cyclooxygenase pathway [GO:0019371]; drug metabolic process [GO:0017144]; epithelial cell differentiation [GO:0030855]; oxidation-reduction process [GO:0055114]; vitamin K metabolic process [GO:0042373]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]	15-hydroxyprostaglandin dehydrogenase (NADP+) activity [GO:0047021]; carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; prostaglandin-E2 9-reductase activity [GO:0050221]
d1kvra__d5ifll___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]; carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d1kvta__d1c1xb1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]; carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d1kvua__d1bg6a2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]; carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	coenzyme binding [GO:0050662]; opine dehydrogenase activity [GO:0047129]	carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]	coenzyme binding [GO:0050662]; opine dehydrogenase activity [GO:0047129]
d1kw1a__d2nv2o___1			Proteobacteria	Firmicutes	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]; glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]		cytosol [GO:0005829]; glutaminase complex [GO:1903600]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]	glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d1kw2a1_d1e7ea3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]; vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1kw2a2_d5orfc2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]; vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]	extracellular space [GO:0005615]	actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]	enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d1kw2b1_d1gnja2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]; vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1kw2b1_d2xvva2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]; vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1kw2b2_d5iiua2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]; vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1kw2b3_d5id7a2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]; vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1kw5a__d2f47a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1kw9b1_d3ojkb1__1			Proteobacteria	Actinobacteria	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]				biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1kwfa__d3a3va___1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	oligosaccharide reducing-end xylanase activity [GO:0033951]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]			cellulase activity [GO:0008810]	oligosaccharide reducing-end xylanase activity [GO:0033951]
d1kwka2_d2vzva3__1			Deinococcus-Thermus	Actinobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; metal ion binding [GO:0046872]; galactose metabolic process [GO:0006012]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	galactose metabolic process [GO:0006012]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	beta-galactosidase activity [GO:0004565]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1kwka3_d4envb2__1			Deinococcus-Thermus	Proteobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; metal ion binding [GO:0046872]; galactose metabolic process [GO:0006012]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	galactose metabolic process [GO:0006012]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	beta-galactosidase complex [GO:0009341]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	beta-galactosidase activity [GO:0004565]; metal ion binding [GO:0046872]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1kwma1_d1qq9a___1	Metazoa		Chordata	Actinobacteria	extracellular space [GO:0005615]; carboxypeptidase activity [GO:0004180]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	proteolysis [GO:0006508]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	carboxypeptidase activity [GO:0004180]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1kwma1_d5lrjc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; carboxypeptidase activity [GO:0004180]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	carboxypeptidase activity [GO:0004180]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1kwua1_d3hupb___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cellular response to drug [GO:0035690]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cellular response to drug [GO:0035690]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]
d1kwub1_d1prth2__1	Metazoa		Chordata	Proteobacteria	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]		collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	toxin activity [GO:0090729]
d1kwvb1_d4m17i___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1kwwb1_d2kmb11__1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d1kwxa1_d3wwkb___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	regulation of cytokine activity [GO:0060300]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1kwxa1_d5bzca___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d1kwxc1_d1rdi1___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]
d1kwyb1_d2it5a___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]
d1kwza1_d4ak8a___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1kwzb1_d1kx1d1__1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d1kx0b1_d3c0mb1__1	Metazoa		Chordata	Proteobacteria	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]		collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; toxin activity [GO:0090729]
d1kx0c1_d2yhfi___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]; cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]
d1kx1a1_d1ypoe___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d1kx1e1_d2bpda___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1kx1f1_d1yu2a2__1	Metazoa		Chordata		collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	virus tail, fiber [GO:0098024]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	
d1kx3e__d1eqzd___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1kx4b__d5b32g___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1kx4b__d5gt0g___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1kx5c__d1zlah___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1kx5e__d5bnxb___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1kx5h__d2pyod___1	Metazoa	Metazoa	Chordata	Arthropoda	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]		chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1kxaa__d1a1r.2__1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]	ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]
d1kxca__d4os2a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]	serine-type endopeptidase activity [GO:0004252]
d1kxea__d2duca___1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1kxfa__d5g4ba___1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1kxgb__d4qq2b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	climbing fiber [GO:0044301]; collagen trimer [GO:0005581]; cytoplasm [GO:0005737]; presynapse [GO:0098793]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; maintenance of synapse structure [GO:0099558]; motor learning [GO:0061743]; neuron remodeling [GO:0016322]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	maintenance of synapse structure [GO:0099558]; motor learning [GO:0061743]; neuron remodeling [GO:0016322]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	climbing fiber [GO:0044301]; collagen trimer [GO:0005581]; cytoplasm [GO:0005737]; presynapse [GO:0098793]; synaptic cleft [GO:0043083]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	signaling receptor binding [GO:0005102]
d1kxge__d5mu8x___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d1kxha2_d1jaea2__1		Metazoa	Proteobacteria	Arthropoda	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1kxma1_d2v2ea___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1kxpa2_d5evzb2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1kxpd3_d3v03a2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1kxqa2_d2pwfa1__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d1kxqa2_d3sctb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d1kxqb1_d1d7fa3__1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1kxqb1_d1xv8a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d1kxra__d2nqia___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]; aging [GO:0007568]; brain development [GO:0007420]; cellular response to hydrogen peroxide [GO:0070301]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of vascular permeability [GO:0043117]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; response to angiotensin [GO:1990776]; response to arsenic-containing substance [GO:0046685]; self proteolysis [GO:0097264]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]; aging [GO:0007568]; brain development [GO:0007420]; cellular response to hydrogen peroxide [GO:0070301]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of vascular permeability [GO:0043117]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; response to angiotensin [GO:1990776]; response to arsenic-containing substance [GO:0046685]; self proteolysis [GO:0097264]	aging [GO:0007568]; brain development [GO:0007420]; cellular response to hydrogen peroxide [GO:0070301]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of vascular permeability [GO:0043117]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; response to angiotensin [GO:1990776]; response to arsenic-containing substance [GO:0046685]; self proteolysis [GO:0097264]	aging [GO:0007568]; brain development [GO:0007420]; cellular response to hydrogen peroxide [GO:0070301]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of vascular permeability [GO:0043117]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; response to angiotensin [GO:1990776]; response to arsenic-containing substance [GO:0046685]; self proteolysis [GO:0097264]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]
d1kxta2_d2pwhb1__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d1kxte1_d1xsid3__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1kxte2_d3ogsa1__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	beta-galactosidase activity [GO:0004565]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	beta-galactosidase activity [GO:0004565]
d1kxvb1_d3l4ta3__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	carbohydrate catabolic process [GO:0016052]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]
d1kxvd__d1lk3h2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]; aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	carbohydrate catabolic process [GO:0016052]	aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]
d1kxwa__d4tsba___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1kxxa__d1l08a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1kxya__d1l52a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ky2a__d3oiwa___1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; fungal-type vacuole membrane [GO:0000329]; late endosome [GO:0005770]; lysosome [GO:0005764]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phagocytic vesicle [GO:0045335]; vacuole-mitochondrion membrane contact site [GO:1990816]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein-containing complex binding [GO:0044877]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; macroautophagy [GO:0016236]; piecemeal microautophagy of the nucleus [GO:0034727]; protein localization to vacuole [GO:0072665]; Rab protein signal transduction [GO:0032482]; regulation of vacuole fusion, non-autophagic [GO:0032889]; retrograde transport, endosome to Golgi [GO:0042147]; vacuole inheritance [GO:0000011]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; macroautophagy [GO:0016236]; piecemeal microautophagy of the nucleus [GO:0034727]; protein localization to vacuole [GO:0072665]; Rab protein signal transduction [GO:0032482]; regulation of vacuole fusion, non-autophagic [GO:0032889]; retrograde transport, endosome to Golgi [GO:0042147]; vacuole inheritance [GO:0000011]; vesicle-mediated transport [GO:0016192]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; fungal-type vacuole membrane [GO:0000329]; late endosome [GO:0005770]; lysosome [GO:0005764]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phagocytic vesicle [GO:0045335]; vacuole-mitochondrion membrane contact site [GO:1990816]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein-containing complex binding [GO:0044877]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1ky4b1_d1keua___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; NADH binding [GO:0070404]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]		adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; NADH binding [GO:0070404]
d1ky4c1_d4ro0p1__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	potassium ion transport [GO:0006813]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1ky4d1_d2fzwb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]
d1ky5a1_d1k0ug1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]
d1ky5d1_d1xltd1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	NAD binding [GO:0051287]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]; NADPH regeneration [GO:0006740]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	NADPH regeneration [GO:0006740]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]		adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]
d1ky6a2_d1r4xa2__1	Metazoa	Metazoa	Chordata	Chordata	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	cell [GO:0005623]; COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; transport vesicle [GO:0030133]; structural molecule activity [GO:0005198]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; establishment of Golgi localization [GO:0051683]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; organelle transport along microtubule [GO:0072384]; protein secretion [GO:0009306]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; establishment of Golgi localization [GO:0051683]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; organelle transport along microtubule [GO:0072384]; protein secretion [GO:0009306]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]	cell [GO:0005623]; COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; transport vesicle [GO:0030133]	clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]	structural molecule activity [GO:0005198]
d1ky7a1_d2vj0a1__1	Metazoa	Metazoa	Chordata	Chordata	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]	clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]	clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]
d1ky7a2_d1pzda2__1	Metazoa	Metazoa	Chordata	Chordata	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; structural molecule activity [GO:0005198]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; organelle transport along microtubule [GO:0072384]; protein secretion [GO:0009306]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; organelle transport along microtubule [GO:0072384]; protein secretion [GO:0009306]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]	COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]	clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]	structural molecule activity [GO:0005198]
d1kyab1_d2llna___1	Fungi		Basidiomycota	Deinococcus-Thermus	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]				integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1kyac2_d4yseb1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1kyad1_d2bp0b1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]			copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1kyad2_d2vdza1__1	Fungi		Basidiomycota		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]						copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	
d1kyba__d1h7ga___1				Proteobacteria		cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]		CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]		cytoplasm [GO:0005737]		3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]
d1kyda1_d1gywa___1	Metazoa	Metazoa	Chordata	Chordata	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]; collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]	clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]	collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]
d1kyga__d4ri7b1__1		Viridiplantae		Streptophyta		cytoplasm [GO:0005737]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]		glutathione metabolic process [GO:0006749]		cytoplasm [GO:0005737]		glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1kyig__d3mg4i___1		Fungi	Proteobacteria	Ascomycota	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein unfolding [GO:0043335]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1kyih__d4qwil___1		Fungi	Proteobacteria	Ascomycota	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein unfolding [GO:0043335]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1kyil__d5l5us___1		Fungi	Proteobacteria	Ascomycota	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein unfolding [GO:0043335]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1kyio__d3gpwt___1		Fungi	Proteobacteria	Ascomycota	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein unfolding [GO:0043335]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1kyiq__d1ai6.1__1			Proteobacteria	Proteobacteria	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	protein unfolding [GO:0043335]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	HslUV protease complex [GO:0009376]	periplasmic space [GO:0042597]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]	metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]
d1kyir__d1g0ud___1		Fungi	Proteobacteria	Ascomycota	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein unfolding [GO:0043335]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1kynb__d2zeba___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; angiotensin maturation [GO:0002003]; antibacterial humoral response [GO:0019731]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of gram-positive bacterium [GO:0070946]; positive regulation of immune response [GO:0050778]; protein phosphorylation [GO:0006468]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	angiotensin maturation [GO:0002003]; antibacterial humoral response [GO:0019731]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of gram-positive bacterium [GO:0070946]; positive regulation of immune response [GO:0050778]; protein phosphorylation [GO:0006468]; proteolysis [GO:0006508]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	azurophil granule lumen [GO:0035578]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	heparin binding [GO:0008201]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1kyob2_d3l75n2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1kyoj__d1it9h1__1	Fungi		Ascomycota		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d1kyok__d1frgl1__1	Fungi		Ascomycota	Negarnaviricota	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	host cell surface receptor binding [GO:0046789]
d1kyoo1_d1ntkd1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1kyoo1_d2gc4d___1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1kyou__d1fl3b1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1kyva__d1kz4b___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]
d1kyvb__d4kq6i___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	mitochondrial intermembrane space [GO:0005758]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	mitochondrial intermembrane space [GO:0005758]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1kyvd__d1c2yn___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1kyve__d2jfbi___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]		cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]		6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	
d1kywa2_d5cvjc2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]; lignin biosynthetic process [GO:0009809]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]	lignin biosynthetic process [GO:0009809]				caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]
d1kywf2_d2p3qa___1	Viridiplantae		Streptophyta		caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]; lignin biosynthetic process [GO:0009809]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	lignin biosynthetic process [GO:0009809]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1kyxc__d1rvv4___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1kyyb__d4gefd___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]		cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]		6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	
d1kyyc__d1kz9e___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]
d1kyza2_d2qyob2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]; lignin biosynthetic process [GO:0009809]	isoflavone 7-O-methyltransferase activity [GO:0033800]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; aromatic compound biosynthetic process [GO:0019438]	lignin biosynthetic process [GO:0009809]	aromatic compound biosynthetic process [GO:0019438]			caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]	isoflavone 7-O-methyltransferase activity [GO:0033800]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d1kyza2_d5ec8a1__1	Viridiplantae		Streptophyta		caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]; lignin biosynthetic process [GO:0009809]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	lignin biosynthetic process [GO:0009809]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1kz1c__d1xn1b___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1kz1d__d1nqva___1	Fungi		Ascomycota	Aquificae	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1kz4c__d4gefb___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]		cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]		6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	
d1kz4e__d1kz6e___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]
d1kz6a__d1c2yo___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1kz7b__d3kkna___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1kz9b__d1c2yk___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1kza2__d2jcpa___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]	epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d1kzc1__d1uosd___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]		collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]	toxin activity [GO:0090729]
d1kzd1__d3rs1a___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; natural killer cell lectin-like receptor binding [GO:0046703]; transmembrane signaling receptor activity [GO:0004888]; membrane raft assembly [GO:0001765]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of immunological synapse formation [GO:2000522]; receptor clustering [GO:0043113]; regulation of actin filament polymerization [GO:0030833]; regulation of interleukin-2 biosynthetic process [GO:0045076]; regulation of T cell proliferation [GO:0042129]; T cell receptor signaling pathway [GO:0050852]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	membrane raft assembly [GO:0001765]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of immunological synapse formation [GO:2000522]; receptor clustering [GO:0043113]; regulation of actin filament polymerization [GO:0030833]; regulation of interleukin-2 biosynthetic process [GO:0045076]; regulation of T cell proliferation [GO:0042129]; T cell receptor signaling pathway [GO:0050852]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]	carbohydrate binding [GO:0030246]; natural killer cell lectin-like receptor binding [GO:0046703]; transmembrane signaling receptor activity [GO:0004888]
d1kzd2__d2rica1__1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1kze1__d1egib___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	cell surface [GO:0009986]; endosome membrane [GO:0010008]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cargo receptor activity [GO:0038024]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	cell surface [GO:0009986]; endosome membrane [GO:0010008]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]	cargo receptor activity [GO:0038024]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]
d1kze1__d4n37c___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1kze2__d5bzja___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]	epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d1kzga1_d2nz8b1__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; histone deacetylase binding [GO:0042826]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cell-matrix adhesion [GO:0007160]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; histone deacetylase binding [GO:0042826]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]
d1kzgb__d221pa___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1kzgd__d3cklb___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytosol [GO:0005829]; aryl sulfotransferase activity [GO:0004062]; sulfotransferase activity [GO:0008146]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; cellular biogenic amine metabolic process [GO:0006576]; epithelial cell differentiation [GO:0030855]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; phenol-containing compound metabolic process [GO:0018958]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; cellular biogenic amine metabolic process [GO:0006576]; epithelial cell differentiation [GO:0030855]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; phenol-containing compound metabolic process [GO:0018958]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	cytosol [GO:0005829]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	aryl sulfotransferase activity [GO:0004062]; sulfotransferase activity [GO:0008146]
d1kzka__d1b11a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d1kzka__d5p6ha___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1kzkb__d3pwmb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1kzma__d1h58a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]	extracellular region [GO:0005576]; vacuole [GO:0005773]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1kzob__d5ikaa1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]; actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d1kzxa__d1opba___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol metabolic process [GO:0042572]	intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	retinol metabolic process [GO:0042572]	cytosol [GO:0005829]	cytosol [GO:0005829]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]	retinal binding [GO:0016918]; retinol binding [GO:0019841]
d1l03a__d3sb8c1__1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l04a__d3ebab___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l05a__d4lt3a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l06a__d3sb5c1__1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l07a__d1jqua___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l07a__d3wvya___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l0ia__d1dv5a___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; D-alanyl carrier activity [GO:0036370]; cell wall organization [GO:0071555]; lipoteichoic acid biosynthetic process [GO:0070395]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	cell wall organization [GO:0071555]; lipoteichoic acid biosynthetic process [GO:0070395]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	D-alanyl carrier activity [GO:0036370]
d1l0ia__d1nq4a___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	antibiotic biosynthetic process [GO:0017000]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	antibiotic biosynthetic process [GO:0017000]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	
d1l0lb1_d1hr9f2__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]; aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]
d1l0na1_d1hr9f1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]; aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]
d1l0na2_d1ezvb2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	
d1l0nd1_d2gc7l___1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1l0ob__d4javb2__1			Firmicutes	Thermotogae	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]; DNA-templated transcription, initiation [GO:0006352]	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; protein autophosphorylation [GO:0046777]	DNA-templated transcription, initiation [GO:0006352]	protein autophosphorylation [GO:0046777]		integral component of plasma membrane [GO:0005887]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d1l0ob__d5j6la___1		Metazoa	Firmicutes	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]; DNA-templated transcription, initiation [GO:0006352]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA-templated transcription, initiation [GO:0006352]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1l0qd1_d1wgoa1__1		Metazoa	Euryarchaeota	Chordata	integral component of membrane [GO:0016021]	cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; perikaryon [GO:0043204]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; recycling endosome membrane [GO:0055038]; neuropeptide receptor activity [GO:0008188]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; neuropeptide signaling pathway [GO:0007218]		intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; neuropeptide signaling pathway [GO:0007218]	integral component of membrane [GO:0016021]	cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; perikaryon [GO:0043204]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; recycling endosome membrane [GO:0055038]		neuropeptide receptor activity [GO:0008188]
d1l0vb1_d1h7wa1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d1l0vb2_d5c2tb1__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d1l0vm3_d1p2ea3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	outer membrane-bounded periplasmic space [GO:0030288]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]
d1l0vn1_d2bs2e1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d1l0wb1_d2j02q1__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]		aspartyl-tRNA aminoacylation [GO:0006422]		cytoplasm [GO:0005737]		aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]	
d1l0wb1_d3a74b1__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	aspartyl-tRNA aminoacylation [GO:0006422]	lysyl-tRNA aminoacylation [GO:0006430]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d1l0xa2_d5t0yb2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d1l0xb2_d2tssb2__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	integral component of membrane [GO:0016021]	extracellular region [GO:0005576]		toxin activity [GO:0090729]
d1l0xd1_d1czwa___1	Metazoa		Chordata		integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	integral component of membrane [GO:0016021]	extracellular region [GO:0005576]		toxin activity [GO:0090729]
d1l0ya1_d1ic5h___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l0ya1_d5ibul2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d1l0ya2_d1h8na2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d1l0yb1_d1s5ee___1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	integral component of membrane [GO:0016021]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]		galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]
d1l0yb1_d2z8la1__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	integral component of membrane [GO:0016021]	extracellular region [GO:0005576]		
d1l0yc1_d2b4cc2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	integral component of membrane [GO:0016021]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1l0yc2_d4fg6d1__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]	integral component of plasma membrane [GO:0005887]; antiporter activity [GO:0015297]; voltage-gated chloride channel activity [GO:0005247]			integral component of membrane [GO:0016021]	integral component of plasma membrane [GO:0005887]		antiporter activity [GO:0015297]; voltage-gated chloride channel activity [GO:0005247]
d1l14a__d2nzba___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]	
d1l16a__d4nhta___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l17a__d166la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l19a__d4prqc___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l1ea__d4pghc2__1		Viridiplantae	Actinobacteria	Streptophyta	cytoplasm [GO:0005737]; cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]; active evasion of host immune response [GO:0042783]; lipid biosynthetic process [GO:0008610]; modulation by symbiont of host innate immune response [GO:0052167]; mycolic acid biosynthetic process [GO:0071768]; pathogenesis [GO:0009405]; S-adenosylmethionine metabolic process [GO:0046500]	acetylserotonin O-methyltransferase activity [GO:0017096]; caffeate O-methyltransferase activity [GO:0047763]; luteolin O-methyltransferase activity [GO:0030744]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; aromatic compound biosynthetic process [GO:0019438]; flavonol biosynthetic process [GO:0051555]; lignin biosynthetic process [GO:0009809]; melatonin biosynthetic process [GO:0030187]	active evasion of host immune response [GO:0042783]; lipid biosynthetic process [GO:0008610]; modulation by symbiont of host innate immune response [GO:0052167]; mycolic acid biosynthetic process [GO:0071768]; pathogenesis [GO:0009405]; S-adenosylmethionine metabolic process [GO:0046500]	aromatic compound biosynthetic process [GO:0019438]; flavonol biosynthetic process [GO:0051555]; lignin biosynthetic process [GO:0009809]; melatonin biosynthetic process [GO:0030187]	cytoplasm [GO:0005737]		cyclopropane-fatty-acyl-phospholipid synthase activity [GO:0008825]	acetylserotonin O-methyltransferase activity [GO:0017096]; caffeate O-methyltransferase activity [GO:0047763]; luteolin O-methyltransferase activity [GO:0030744]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d1l1fa2_d2egga1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1l1fb1_d5uawd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1l1fc1_d3etgc2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1l1fd2_d3mw9f2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	
d1l1fd2_d5dzsa1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1l1ff2_d3mw9e2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	
d1l1ga__d2amqb___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1l1na__d1sgqe___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1l1pa1_d3o5fa___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; 'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]; response to heat [GO:0009408]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1l1ya__d1wu6a1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	oligosaccharide reducing-end xylanase activity [GO:0033951]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]	oligosaccharide reducing-end xylanase activity [GO:0033951]
d1l1yb__d5gxxa1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1l1yd__d4zh5b___1		Metazoa	Firmicutes	Annelida	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]
d1l1yf__d2gh4a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cytoplasm [GO:0005737]; unsaturated rhamnogalacturonyl hydrolase activity [GO:0102211]; metabolic process [GO:0008152]	cellulose catabolic process [GO:0030245]	metabolic process [GO:0008152]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]	unsaturated rhamnogalacturonyl hydrolase activity [GO:0102211]
d1l20a__d1l97a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l23a__d3hu8a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l25a__d1dyda___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l27a__d4cj2a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l28a__d1pqkc___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l29a__d1jnac___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]	
d1l29a__d1ov7a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l2ab__d3wkha___1			Firmicutes	Bacteroidetes	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cellobiose epimerase activity [GO:0047736]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]	cellobiose epimerase activity [GO:0047736]
d1l2ac__d1h14a___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d1l2ae__d5gxzb1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1l2da1_d1kfvb1__1				Firmicutes		class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]		base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]				class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]
d1l2ea__d1gbja___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]; serine-type endopeptidase activity [GO:0004252]; amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]	extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1l2gb__d1op3m1__1					integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; metal ion binding [GO:0046872]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]		entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]		integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		metal ion binding [GO:0046872]	
d1l2gd__d8faba2__1					integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; metal ion binding [GO:0046872]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]		entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]		integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		metal ion binding [GO:0046872]	
d1l2wa__d1ttwa___1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; GTPase activator activity [GO:0005096]; negative regulation of phagocytosis [GO:0050765]; pathogenesis [GO:0009405]	protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	negative regulation of phagocytosis [GO:0050765]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]		GTPase activator activity [GO:0005096]	protein tyrosine phosphatase activity [GO:0004725]
d1l2wa__d4jmfb___1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; GTPase activator activity [GO:0005096]; negative regulation of phagocytosis [GO:0050765]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; GTPase activator activity [GO:0005096]; pathogenesis [GO:0009405]	negative regulation of phagocytosis [GO:0050765]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]	extracellular region [GO:0005576]	GTPase activator activity [GO:0005096]	GTPase activator activity [GO:0005096]
d1l2wc__d1jyod___1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; GTPase activator activity [GO:0005096]; negative regulation of phagocytosis [GO:0050765]; pathogenesis [GO:0009405]	extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; GTPase activator activity [GO:0005096]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	negative regulation of phagocytosis [GO:0050765]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]	extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]	GTPase activator activity [GO:0005096]	GTPase activator activity [GO:0005096]; protein tyrosine phosphatase activity [GO:0004725]
d1l2wd__d1k3eb___1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; GTPase activator activity [GO:0005096]; negative regulation of phagocytosis [GO:0050765]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; pathogenesis [GO:0009405]; regulation of protein secretion [GO:0050708]	negative regulation of phagocytosis [GO:0050765]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]; regulation of protein secretion [GO:0050708]	cell outer membrane [GO:0009279]	cytoplasm [GO:0005737]	GTPase activator activity [GO:0005096]	
d1l30a__d3b0oa1__1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	host cell cytoplasm [GO:0030430]	extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]	lysozyme activity [GO:0003796]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]
d1l32a__d1b6ia___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l33a__d3ru5a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l33a__d4i7nb1__1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l35a__d4etca___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l37a__d231la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l38a__d1gf8a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l39a__d4yf2a1__1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	acrosomal matrix [GO:0043159]; acrosomal membrane [GO:0002080]; acrosomal vesicle [GO:0001669]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; secretory granule [GO:0030141]; lysozyme activity [GO:0003796]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; sperm-egg recognition [GO:0035036]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; sperm-egg recognition [GO:0035036]	host cell cytoplasm [GO:0030430]	acrosomal matrix [GO:0043159]; acrosomal membrane [GO:0002080]; acrosomal vesicle [GO:0001669]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; secretory granule [GO:0030141]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l3fe__d3fgda___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1l3sa1_d4dtna1__1			Firmicutes		3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1l3va1_d4ktqa1__1			Firmicutes	Deinococcus-Thermus	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]
d1l3wa1_d3lndb1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Notch signaling pathway [GO:0007219]	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Notch signaling pathway [GO:0007219]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d1l3wa1_d3lnhb1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	calcium ion binding [GO:0005509]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d1l3wa2_d4zmya1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d1l3wa3_d4zmla1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d1l3wa5_d1l3wa2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]
d1l43a__d3hh3a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l43a__d5njpa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l44a__d173la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l45a__d3rt5x___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l46a__d4agaa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l49a__d1o23c___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	host cell cytoplasm [GO:0030430]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	lysozyme activity [GO:0003796]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1l4ba__d4kqga___1			Proteobacteria	Proteobacteria	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity [GO:0008939]; nucleotide binding [GO:0000166]; cobalamin biosynthetic process [GO:0009236]; nucleoside biosynthetic process [GO:0009163]	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity [GO:0008939]; nucleotide binding [GO:0000166]; cobalamin biosynthetic process [GO:0009236]; nucleoside biosynthetic process [GO:0009163]	cobalamin biosynthetic process [GO:0009236]; nucleoside biosynthetic process [GO:0009163]	cobalamin biosynthetic process [GO:0009236]; nucleoside biosynthetic process [GO:0009163]			nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity [GO:0008939]; nucleotide binding [GO:0000166]	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity [GO:0008939]; nucleotide binding [GO:0000166]
d1l4da__d2b7dh___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; other organism cell membrane [GO:0044218]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; Schaffer collateral - CA1 synapse [GO:0098685]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; kinase binding [GO:0019900]; proteasome core complex binding [GO:1904854]; protein antigen binding [GO:1990405]; protein domain specific binding [GO:0019904]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; extracellular matrix disassembly [GO:0022617]; fibrinolysis [GO:0042730]; interaction with symbiont [GO:0051702]; interaction with symbiont via secreted substance [GO:0052213]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of fibrinolysis [GO:0051918]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trophoblast giant cell differentiation [GO:0060707]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; extracellular matrix disassembly [GO:0022617]; fibrinolysis [GO:0042730]; interaction with symbiont [GO:0051702]; interaction with symbiont via secreted substance [GO:0052213]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of fibrinolysis [GO:0051918]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trophoblast giant cell differentiation [GO:0060707]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; other organism cell membrane [GO:0044218]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; Schaffer collateral - CA1 synapse [GO:0098685]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; kinase binding [GO:0019900]; proteasome core complex binding [GO:1904854]; protein antigen binding [GO:1990405]; protein domain specific binding [GO:0019904]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d1l4na__d4kqja___1			Proteobacteria	Proteobacteria	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity [GO:0008939]; nucleotide binding [GO:0000166]; cobalamin biosynthetic process [GO:0009236]; nucleoside biosynthetic process [GO:0009163]	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity [GO:0008939]; nucleotide binding [GO:0000166]; cobalamin biosynthetic process [GO:0009236]; nucleoside biosynthetic process [GO:0009163]	cobalamin biosynthetic process [GO:0009236]; nucleoside biosynthetic process [GO:0009163]	cobalamin biosynthetic process [GO:0009236]; nucleoside biosynthetic process [GO:0009163]			nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity [GO:0008939]; nucleotide binding [GO:0000166]	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity [GO:0008939]; nucleotide binding [GO:0000166]
d1l51a__d1d9wa___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l52a__d200la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l54a__d4qwpa___1				Proteobacteria	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; chitosanase activity [GO:0016977]; carbohydrate metabolic process [GO:0005975]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	carbohydrate metabolic process [GO:0005975]	host cell cytoplasm [GO:0030430]	extracellular region [GO:0005576]	lysozyme activity [GO:0003796]	chitosanase activity [GO:0016977]
d1l5aa1_d2h4ta1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; enterobactin synthetase complex [GO:0009366]; 2,3-dihydroxybenzoate-serine ligase activity [GO:0047527]; acid-ammonia (or amide) ligase activity [GO:0016880]; phosphopantetheine binding [GO:0031177]; amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; enterobactin biosynthetic process [GO:0009239]; secondary metabolite biosynthetic process [GO:0044550]; siderophore biosynthetic process [GO:0019290]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; enterobactin biosynthetic process [GO:0009239]; secondary metabolite biosynthetic process [GO:0044550]; siderophore biosynthetic process [GO:0019290]	fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; enterobactin synthetase complex [GO:0009366]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	2,3-dihydroxybenzoate-serine ligase activity [GO:0047527]; acid-ammonia (or amide) ligase activity [GO:0016880]; phosphopantetheine binding [GO:0031177]	carnitine O-palmitoyltransferase activity [GO:0004095]
d1l5ga1_d3ijea3__1	Metazoa	Metazoa	Chordata	Chordata	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; cell [GO:0005623]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin alphav-beta5 complex [GO:0034684]; integrin alphav-beta6 complex [GO:0034685]; integrin alphav-beta8 complex [GO:0034686]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; microvillus membrane [GO:0031528]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; specific granule membrane [GO:0035579]; coreceptor activity [GO:0015026]; extracellular matrix binding [GO:0050840]; extracellular matrix protein binding [GO:1990430]; fibronectin binding [GO:0001968]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; opsonin binding [GO:0001846]; protease binding [GO:0002020]; protein kinase C binding [GO:0005080]; transforming growth factor beta binding [GO:0050431]; virus receptor activity [GO:0001618]; voltage-gated calcium channel activity [GO:0005245]; angiogenesis [GO:0001525]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; endodermal cell differentiation [GO:0035987]; entry of symbiont into host cell by promotion of host phagocytosis [GO:0052066]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; negative chemotaxis [GO:0050919]; negative regulation of entry of bacterium into host cell [GO:2000536]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; neutrophil degranulation [GO:0043312]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of phagocytosis [GO:0050764]; regulation of transforming growth factor beta activation [GO:1901388]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor-beta secretion [GO:0038044]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral entry into host cell [GO:0046718]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	angiogenesis [GO:0001525]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; endodermal cell differentiation [GO:0035987]; entry of symbiont into host cell by promotion of host phagocytosis [GO:0052066]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; negative chemotaxis [GO:0050919]; negative regulation of entry of bacterium into host cell [GO:2000536]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; neutrophil degranulation [GO:0043312]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of phagocytosis [GO:0050764]; regulation of transforming growth factor beta activation [GO:1901388]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor-beta secretion [GO:0038044]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral entry into host cell [GO:0046718]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; cell [GO:0005623]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin alphav-beta5 complex [GO:0034684]; integrin alphav-beta6 complex [GO:0034685]; integrin alphav-beta8 complex [GO:0034686]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; microvillus membrane [GO:0031528]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; specific granule membrane [GO:0035579]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	coreceptor activity [GO:0015026]; extracellular matrix binding [GO:0050840]; extracellular matrix protein binding [GO:1990430]; fibronectin binding [GO:0001968]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; opsonin binding [GO:0001846]; protease binding [GO:0002020]; protein kinase C binding [GO:0005080]; transforming growth factor beta binding [GO:0050431]; virus receptor activity [GO:0001618]; voltage-gated calcium channel activity [GO:0005245]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]
d1l5pc__d1n63d2__1				Proteobacteria	hydrogenosome [GO:0042566]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]			hydrogenosome [GO:0042566]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1l5vb__d1gpba___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; maltodextrin phosphorylase activity [GO:0031220]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]; alpha-glucan catabolic process [GO:0030980]; glycogen catabolic process [GO:0005980]	skeletal muscle myofibril [GO:0098723]; glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]; glycogen metabolic process [GO:0005977]	alpha-glucan catabolic process [GO:0030980]; glycogen catabolic process [GO:0005980]	glycogen metabolic process [GO:0005977]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	skeletal muscle myofibril [GO:0098723]	glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; maltodextrin phosphorylase activity [GO:0031220]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]	glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]
d1l5vb__d1jiua___1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; maltodextrin phosphorylase activity [GO:0031220]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]; alpha-glucan catabolic process [GO:0030980]; glycogen catabolic process [GO:0005980]	DNA beta-glucosyltransferase activity [GO:0033821]; DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]	alpha-glucan catabolic process [GO:0030980]; glycogen catabolic process [GO:0005980]	DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; maltodextrin phosphorylase activity [GO:0031220]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]	DNA beta-glucosyltransferase activity [GO:0033821]
d1l5ya1_d2ayxa2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; cellular response to osmotic stress [GO:0071470]; phosphorelay signal transduction system [GO:0000160]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]; single-species biofilm formation [GO:0044010]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cellular response to osmotic stress [GO:0071470]; phosphorelay signal transduction system [GO:0000160]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]; single-species biofilm formation [GO:0044010]	cytoplasm [GO:0005737]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]
d1l5yb1_d2jbab___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1l60a__d1dyea___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l65a__d1l89a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l68a__d1cuqa___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l68a__d3lhma___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l6ma__d2w2fc___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	carboxy-lyase activity [GO:0016831]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]		enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	carboxy-lyase activity [GO:0016831]
d1l6rb1_d1rltb___1			Euryarchaeota	Proteobacteria	magnesium ion binding [GO:0000287]; phosphoglycolate phosphatase activity [GO:0008967]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	carbohydrate metabolic process [GO:0005975]			cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; phosphoglycolate phosphatase activity [GO:0008967]	magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]
d1l6rb1_d4mwoa___1		Metazoa	Euryarchaeota	Chordata	magnesium ion binding [GO:0000287]; phosphoglycolate phosphatase activity [GO:0008967]; carbohydrate metabolic process [GO:0005975]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	carbohydrate metabolic process [GO:0005975]	DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	magnesium ion binding [GO:0000287]; phosphoglycolate phosphatase activity [GO:0008967]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]
d1l6va__d1v97a2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	xanthine catabolic process [GO:0009115]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1l6wa__d1qfea___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	fructose metabolic process [GO:0006000]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]		fructose 6-phosphate aldolase activity [GO:0097023]	3-dehydroquinate dehydratase activity [GO:0003855]
d1l6wb__d4cnpa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	fructose metabolic process [GO:0006000]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]		fructose 6-phosphate aldolase activity [GO:0097023]	3-dehydroquinate dehydratase activity [GO:0003855]
d1l6wb__d4i7uc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]; pyruvate metabolic process [GO:0006090]	fructose metabolic process [GO:0006000]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]; pyruvate metabolic process [GO:0006090]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	fructose 6-phosphate aldolase activity [GO:0097023]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1l6wc__d2qapd___1			Proteobacteria		cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	fructose metabolic process [GO:0006000]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]		fructose 6-phosphate aldolase activity [GO:0097023]	fructose-bisphosphate aldolase activity [GO:0004332]
d1l6we__d1zaic___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	fructose metabolic process [GO:0006000]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]	I band [GO:0031674]; M band [GO:0031430]	fructose 6-phosphate aldolase activity [GO:0097023]	fructose-bisphosphate aldolase activity [GO:0004332]
d1l6wf__d5dbtc___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	fructose metabolic process [GO:0006000]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	fructose 6-phosphate aldolase activity [GO:0097023]	deoxyribose-phosphate aldolase activity [GO:0004139]
d1l6xa2_d1hhia1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1l70a__d3wu9a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l72a__d3wl2b___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l73a__d5fsta___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l7aa__d1u2eb___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	cytoplasm [GO:0005737]; 2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity [GO:0052823]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; 3-(3-hydroxy)phenylpropionate catabolic process [GO:0019622]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	3-(3-hydroxy)phenylpropionate catabolic process [GO:0019622]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]	2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity [GO:0052823]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]
d1l7fa__d4gdie___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1l7ha__d3beqb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1l7il1_d3vgab2__1	Metazoa	Metazoa	Chordata	Chordata		axolemma [GO:0030673]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; intermediate filament [GO:0005882]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; alpha-actinin binding [GO:0051393]; enzyme binding [GO:0019899]; G protein-coupled adenosine receptor activity [GO:0001609]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; type 5 metabotropic glutamate receptor binding [GO:0031802]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; cellular protein metabolic process [GO:0044267]; central nervous system development [GO:0007417]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of transcription, DNA-templated [GO:0006355]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; sensory perception [GO:0007600]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311]		adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; cellular protein metabolic process [GO:0044267]; central nervous system development [GO:0007417]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of transcription, DNA-templated [GO:0006355]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; sensory perception [GO:0007600]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311]		axolemma [GO:0030673]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; intermediate filament [GO:0005882]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]		alpha-actinin binding [GO:0051393]; enzyme binding [GO:0019899]; G protein-coupled adenosine receptor activity [GO:0001609]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d1l7kb1_d4ttga5__1			Firmicutes	Proteobacteria	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1l7sh3_d5w06l2__1		Metazoa		Chordata		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]		activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]		cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]
d1l7sh4_d4kklf1__1				Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1l7th1_d1bqhb___1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1l7th2_d4ma1l1__1	Metazoa		Chordata									
d1l7tl2_d1jvkb1__1	Metazoa	Metazoa	Chordata	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1l7tl2_d4kkle2__1	Metazoa		Chordata	Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1l7wb1_d4ho2a___1				Firmicutes		glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]		extracellular polysaccharide biosynthetic process [GO:0045226]				glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1l7ya__d4hk2d1__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein K69-linked ufmylation [GO:1990592]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	protein K69-linked ufmylation [GO:1990592]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]		protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1l85a__d1jttl___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l86a__d3atoa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l87a__d2d4ia___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l89a__d193la___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l8aa3_d3exgl2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1l8ha__d5k52a___1			Proteobacteria	Cyanobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]		cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]
d1l8hd__d3qd8a___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1l8he__d2fjcc___1			Proteobacteria	Spirochaetes	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1l8hf__d1oq4e___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	chloroplast [GO:0009507]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d1l8hh__d3a9qs___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1l8hi__d3uofa___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1l8hi__d5d8re___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1l8hj__d2jd6h___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d1l8ic__d2jd6o___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d1l8ic__d4dyud___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytoplasm [GO:0005737]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1l8ie__d2fjcg___1			Proteobacteria	Spirochaetes	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1l8ie__d4z3ba___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1l8ig__d1kgod___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ribonucleoside-diphosphate reductase complex [GO:0005971]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1l8ig__d1qghf___1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytoplasm [GO:0005737]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1l8ih__d3qb9e___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1l8ij__d4toel___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1l8ij__d5d8rg___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1l8ik__d3kx9t___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]
d1l8il__d1j30a___1			Proteobacteria	Crenarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]		cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d1l8ja__d1t7za2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; centrosome [GO:0005813]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; blood coagulation [GO:0007596]; negative regulation of coagulation [GO:0050819]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	blood coagulation [GO:0007596]; negative regulation of coagulation [GO:0050819]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	cell surface [GO:0009986]; centrosome [GO:0005813]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	signaling receptor activity [GO:0038023]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]
d1l8pb1_d3ozmd2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cellular amino acid catabolic process [GO:0009063]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	metal ion binding [GO:0046872]
d1l8ya1_d1j3xa___1	Metazoa	Metazoa	Chordata	Chordata	fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA binding [GO:0003723]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]; RNA polymerase I upstream control element sequence-specific DNA binding [GO:0001165]; scaffold protein binding [GO:0097110]; positive regulation of transcription by RNA polymerase I [GO:0045943]; regulation of transcription by RNA polymerase I [GO:0006356]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase I [GO:0006360]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]	cell [GO:0005623]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; enhancer sequence-specific DNA binding [GO:0001158]; four-way junction DNA binding [GO:0000400]; non-sequence-specific DNA binding, bending [GO:0044378]; protein domain specific binding [GO:0019904]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription factor binding [GO:0008134]; chemotaxis [GO:0006935]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; DNA geometric change [GO:0032392]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA topological change [GO:0006265]; inflammatory response to antigenic stimulus [GO:0002437]; innate immune response [GO:0045087]; male gonad development [GO:0008584]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of gene expression [GO:0010629]; nucleosome assembly [GO:0006334]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]; response to steroid hormone [GO:0048545]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]	positive regulation of transcription by RNA polymerase I [GO:0045943]; regulation of transcription by RNA polymerase I [GO:0006356]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase I [GO:0006360]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]	chemotaxis [GO:0006935]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; DNA geometric change [GO:0032392]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA topological change [GO:0006265]; inflammatory response to antigenic stimulus [GO:0002437]; innate immune response [GO:0045087]; male gonad development [GO:0008584]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of gene expression [GO:0010629]; nucleosome assembly [GO:0006334]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]; response to steroid hormone [GO:0048545]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]	fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA binding [GO:0003723]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]; RNA polymerase I upstream control element sequence-specific DNA binding [GO:0001165]; scaffold protein binding [GO:0097110]	DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; enhancer sequence-specific DNA binding [GO:0001158]; four-way junction DNA binding [GO:0000400]; non-sequence-specific DNA binding, bending [GO:0044378]; protein domain specific binding [GO:0019904]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription factor binding [GO:0008134]
d1l93a__d5wrba___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l99a__d3aw7a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1l99a__d3sb5a1__1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1l9bc__d1ntkd1__1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1l9ca2_d2ejra3__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	DNA repair complex [GO:1990391]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; androgen receptor binding [GO:0050681]; chromatin binding [GO:0003682]; demethylase activity [GO:0032451]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-dimethyl-K4 specific) [GO:0034648]; histone demethylase activity (H3-K4 specific) [GO:0032453]; histone demethylase activity (H3-K9 specific) [GO:0032454]; MRF binding [GO:0043426]; nuclear receptor transcription coactivator activity [GO:0030374]; oxidoreductase activity [GO:0016491]; p53 binding [GO:0002039]; RNA polymerase II transcription factor binding [GO:0001085]; telomeric DNA binding [GO:0042162]; telomeric repeat-containing RNA binding [GO:0061752]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; alternative mRNA splicing, via spliceosome [GO:0000380]; blood coagulation [GO:0007596]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; histone H3-K9 demethylation [GO:0033169]; muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron maturation [GO:0042551]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of histone ubiquitination [GO:0033184]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of cellular protein localization [GO:1903827]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fungicide [GO:0060992]	tetrahydrofolate metabolic process [GO:0046653]	alternative mRNA splicing, via spliceosome [GO:0000380]; blood coagulation [GO:0007596]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; histone H3-K9 demethylation [GO:0033169]; muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron maturation [GO:0042551]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of histone ubiquitination [GO:0033184]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of cellular protein localization [GO:1903827]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fungicide [GO:0060992]	cytoplasm [GO:0005737]	DNA repair complex [GO:1990391]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]	sarcosine oxidase activity [GO:0008115]	androgen receptor binding [GO:0050681]; chromatin binding [GO:0003682]; demethylase activity [GO:0032451]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-dimethyl-K4 specific) [GO:0034648]; histone demethylase activity (H3-K4 specific) [GO:0032453]; histone demethylase activity (H3-K9 specific) [GO:0032454]; MRF binding [GO:0043426]; nuclear receptor transcription coactivator activity [GO:0030374]; oxidoreductase activity [GO:0016491]; p53 binding [GO:0002039]; RNA polymerase II transcription factor binding [GO:0001085]; telomeric DNA binding [GO:0042162]; telomeric repeat-containing RNA binding [GO:0061752]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1l9cb2_d1daoh2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	tetrahydrofolate metabolic process [GO:0046653]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	sarcosine oxidase activity [GO:0008115]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d1l9cb2_d1pxaa2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	tetrahydrofolate metabolic process [GO:0046653]	benzoate catabolic process via hydroxylation [GO:0043640]	cytoplasm [GO:0005737]		sarcosine oxidase activity [GO:0008115]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1l9da2_d1h82b2__1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	tetrahydrofolate metabolic process [GO:0046653]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	cytoplasm [GO:0005737]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	sarcosine oxidase activity [GO:0008115]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]
d1l9eb2_d2xfnb2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	tetrahydrofolate metabolic process [GO:0046653]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	sarcosine oxidase activity [GO:0008115]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1l9fa4_d1cf3a2__1		Fungi		Ascomycota		extracellular region [GO:0005576]; flavin adenine dinucleotide binding [GO:0050660]; glucose oxidase activity [GO:0046562]				extracellular region [GO:0005576]		flavin adenine dinucleotide binding [GO:0050660]; glucose oxidase activity [GO:0046562]
d1l9fb4_d1pxba2__1				Proteobacteria		4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]		benzoate catabolic process via hydroxylation [GO:0043640]				4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1l9ma2_d4pyge4__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1l9mb4_d1sgxa6__1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]		cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]		calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]	
d1l9nb4_d1qrkb4__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1l9oa1_d1zv2a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1l9oa1_d5n0ka4__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	anchored component of plasma membrane [GO:0046658]; cell [GO:0005623]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; aging [GO:0007568]; cellular iron ion homeostasis [GO:0006879]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; liver development [GO:0001889]; lung development [GO:0030324]; plasma membrane copper ion transport [GO:0015679]; response to copper ion [GO:0046688]; response to nutrient [GO:0007584]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	aging [GO:0007568]; cellular iron ion homeostasis [GO:0006879]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; liver development [GO:0001889]; lung development [GO:0030324]; plasma membrane copper ion transport [GO:0015679]; response to copper ion [GO:0046688]; response to nutrient [GO:0007584]	periplasmic space [GO:0042597]	anchored component of plasma membrane [GO:0046658]; cell [GO:0005623]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d1l9oa2_d3t6xc2__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1l9ob1_d4knua2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1l9ob2_d2dyro1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1l9oc2_d5ndcb2__1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1l9pb1_d1cywa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cytochrome o ubiquinol oxidase complex [GO:0009319]; integral component of external side of plasma membrane [GO:0071575]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome bo3 ubiquinol oxidase activity [GO:0009486]; cytochrome o ubiquinol oxidase activity [GO:0008827]; cytochrome-c oxidase activity [GO:0004129]; electron transfer activity [GO:0009055]; oxidoreduction-driven active transmembrane transporter activity [GO:0015453]; proton transmembrane transporter activity [GO:0015078]; ubiquinone binding [GO:0048039]; aerobic electron transport chain [GO:0019646]; aerobic respiration [GO:0009060]; ATP synthesis coupled electron transport [GO:0042773]; electron transport coupled proton transport [GO:0015990]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	aerobic electron transport chain [GO:0019646]; aerobic respiration [GO:0009060]; ATP synthesis coupled electron transport [GO:0042773]; electron transport coupled proton transport [GO:0015990]	periplasmic space [GO:0042597]	cytochrome o ubiquinol oxidase complex [GO:0009319]; integral component of external side of plasma membrane [GO:0071575]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome bo3 ubiquinol oxidase activity [GO:0009486]; cytochrome-c oxidase activity [GO:0004129]; cytochrome o ubiquinol oxidase activity [GO:0008827]; electron transfer activity [GO:0009055]; oxidoreduction-driven active transmembrane transporter activity [GO:0015453]; proton transmembrane transporter activity [GO:0015078]; ubiquinone binding [GO:0048039]
d1l9pb2_d1e5zd___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1l9pb2_d5ue6g2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1l9pc1_d1ic0d___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	metal ion binding [GO:0046872]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	metal ion binding [GO:0046872]
d1l9pc1_d1j9ra2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1l9qa1_d4bxva___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1l9qa2_d1sjmb2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1l9qb2_d2pcya___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1l9qc1_d4a67a3__1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	sporulation resulting in formation of a cellular spore [GO:0030435]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1l9qc2_d4g7sb2__1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1l9ra1_d1gy2b___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1l9ra2_d4azub___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1l9rc1_d5ue6d1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1l9sa2_d1qnib1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	membrane [GO:0016020]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	membrane [GO:0016020]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d1l9sc2_d3ag1o2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1l9tc1_d2gi0b___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1l9tc2_d1ag0a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1l9va2_d2gu0b1__1					host cell cytoplasm [GO:0030430]; ATP binding [GO:0005524]; hydrolase activity, acting on acid anhydrides [GO:0016817]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; viral genome replication [GO:0019079]	host cell cytoplasm [GO:0030430]; ATP binding [GO:0005524]; hydrolase activity, acting on acid anhydrides [GO:0016817]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; viral genome replication [GO:0019079]	viral genome replication [GO:0019079]	viral genome replication [GO:0019079]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	ATP binding [GO:0005524]; hydrolase activity, acting on acid anhydrides [GO:0016817]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; hydrolase activity, acting on acid anhydrides [GO:0016817]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d1l9xa__d1gg9a1__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; vacuole [GO:0005773]; exopeptidase activity [GO:0008238]; gamma-glutamyl-peptidase activity [GO:0034722]; omega peptidase activity [GO:0008242]; neutrophil degranulation [GO:0043312]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	neutrophil degranulation [GO:0043312]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; vacuole [GO:0005773]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	exopeptidase activity [GO:0008238]; gamma-glutamyl-peptidase activity [GO:0034722]; omega peptidase activity [GO:0008242]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1l9xc__d4p35a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; vacuole [GO:0005773]; exopeptidase activity [GO:0008238]; gamma-glutamyl-peptidase activity [GO:0034722]; omega peptidase activity [GO:0008242]; neutrophil degranulation [GO:0043312]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	neutrophil degranulation [GO:0043312]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; vacuole [GO:0005773]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]	exopeptidase activity [GO:0008238]; gamma-glutamyl-peptidase activity [GO:0034722]; omega peptidase activity [GO:0008242]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]
d1l9ya__d5iqkb___1			Proteobacteria		beta-lactamase activity [GO:0008800]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					beta-lactamase activity [GO:0008800]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1l9yb__d1e5db2__1			Proteobacteria	Proteobacteria	beta-lactamase activity [GO:0008800]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; respiratory electron transport chain [GO:0022904]		respiratory electron transport chain [GO:0022904]			beta-lactamase activity [GO:0008800]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1laaa__d1l94a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1laaa__d4g4ba___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1laca__d1ghja___1			Firmicutes	Proteobacteria	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	oxoglutarate dehydrogenase complex [GO:0045252]; dihydrolipoyllysine-residue succinyltransferase activity [GO:0004149]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; tricarboxylic acid cycle [GO:0006099]		oxoglutarate dehydrogenase complex [GO:0045252]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]	dihydrolipoyllysine-residue succinyltransferase activity [GO:0004149]
d1lage__d1nfta___1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; amino acid transport [GO:0006865]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	amino acid transport [GO:0006865]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]		ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]
d1laja__d5c4wb___1					T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1lajb__d4ceyb___1					T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1lama1_d7cpaa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1lama2_d1gyti1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]		peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]
d1lama2_d5cb5a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]; negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]		negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]		aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]
d1lana1_d1gytb1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]		peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]
d1lapa1_d2pj4a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1lara2_d4wtya___1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; chondroitin sulfate proteoglycan binding [GO:0035373]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; protein-containing complex binding [GO:0044877]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]	protein tyrosine phosphatase activity [GO:0004725]	cell adhesion [GO:0007155]; cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]		extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]		cell adhesion molecule binding [GO:0050839]; chondroitin sulfate proteoglycan binding [GO:0035373]; heparin binding [GO:0008201]; protein-containing complex binding [GO:0044877]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	protein tyrosine phosphatase activity [GO:0004725]
d1laue__d1okbb___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]	base-excision repair [GO:0006284]	base-excision repair [GO:0006284]	host cell nucleus [GO:0042025]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d1lava__d1hpza1__1			Proteobacteria		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1laxa__d3jzja___1			Proteobacteria	Actinobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	
d1lb1c1_d5jhge1__1	Metazoa	Metazoa	Chordata	Chordata	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d1lb1d__d4f7wa___1	Metazoa		Chordata	Proteobacteria	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	coenzyme A biosynthetic process [GO:0015937]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d1lb1f__d2zyvx___1	Metazoa	Metazoa	Chordata	Chordata	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; aryl sulfotransferase activity [GO:0004062]; sulfotransferase activity [GO:0008146]; catecholamine metabolic process [GO:0006584]; lipid metabolic process [GO:0006629]; sulfate assimilation [GO:0000103]; sulfation [GO:0051923]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	catecholamine metabolic process [GO:0006584]; lipid metabolic process [GO:0006629]; sulfate assimilation [GO:0000103]; sulfation [GO:0051923]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]	aryl sulfotransferase activity [GO:0004062]; sulfotransferase activity [GO:0008146]
d1lb1h__d2c8va___1	Metazoa		Chordata	Proteobacteria	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	nitrogen fixation [GO:0009399]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	molybdenum-iron nitrogenase complex [GO:0016612]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1lb6a__d2an6d1__1	Metazoa	Metazoa	Chordata	Chordata	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase B binding [GO:0043422]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; membrane protein intracellular domain proteolysis [GO:0031293]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neural tube closure [GO:0001843]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; regulation of immunoglobulin secretion [GO:0051023]; response to interleukin-1 [GO:0070555]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; toll-like receptor 9 signaling pathway [GO:0034162]; toll-like receptor signaling pathway [GO:0002224]	beta-catenin destruction complex [GO:0030877]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; SCF ubiquitin ligase complex [GO:0019005]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; post-embryonic development [GO:0009791]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; in utero embryonic development [GO:0001701]; JNK cascade [GO:0007254]; membrane protein intracellular domain proteolysis [GO:0031293]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; regulation of immunoglobulin secretion [GO:0051023]; response to interleukin-1 [GO:0070555]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; toll-like receptor 9 signaling pathway [GO:0034162]; toll-like receptor signaling pathway [GO:0002224]	cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; post-embryonic development [GO:0009791]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	beta-catenin destruction complex [GO:0030877]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; SCF ubiquitin ligase complex [GO:0019005]	histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase B binding [GO:0043422]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1lb8a1_d4m4ga___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; cysteine biosynthetic process [GO:0019344]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cysteine biosynthetic process [GO:0019344]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1lbba__d3vveb1__1	Metazoa		Chordata	Deinococcus-Thermus	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	membrane [GO:0016020]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ligand-gated ion channel activity [GO:0015276]
d1lbca__d2y7rf___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1lbcb1_d3rn8a___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1lbcc__d4kpta___1	Metazoa		Chordata	Firmicutes	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	nitrogen compound transport [GO:0071705]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ligand-gated ion channel activity [GO:0015276]
d1lbgb2_d3ma0c___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	outer membrane-bounded periplasmic space [GO:0030288]; monosaccharide binding [GO:0048029]; D-xylose metabolic process [GO:0042732]; D-xylose transmembrane transport [GO:0015753]	negative regulation of transcription, DNA-templated [GO:0045892]	D-xylose metabolic process [GO:0042732]; D-xylose transmembrane transport [GO:0015753]	cytosol [GO:0005829]	outer membrane-bounded periplasmic space [GO:0030288]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]	monosaccharide binding [GO:0048029]
d1lbhb__d1usic___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	outer membrane-bounded periplasmic space [GO:0030288]; leucine binding [GO:0070728]; leucine transport [GO:0015820]	negative regulation of transcription, DNA-templated [GO:0045892]	leucine transport [GO:0015820]	cytosol [GO:0005829]	outer membrane-bounded periplasmic space [GO:0030288]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]	leucine binding [GO:0070728]
d1lbka2_d5b8ac___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]; activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]
d1lbla__d3o07c___1		Fungi	Crenarchaeota	Ascomycota	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	tryptophan biosynthetic process [GO:0000162]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]		glutaminase complex [GO:1903600]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d1lbsc__d1ku0a___1	Fungi		Basidiomycota	Firmicutes	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d1lbtb__d1tgla___1	Fungi	Fungi	Basidiomycota	Mucoromycota	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]			triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d1lbua2_d4c4ma___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; zinc D-Ala-D-Ala carboxypeptidase activity [GO:0009046]; cell wall organization [GO:0071555]	axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]; transport vesicle [GO:0030133]; calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; laminin-1 binding [GO:0043237]; patched binding [GO:0005113]; zinc ion binding [GO:0008270]; anatomical structure development [GO:0048856]; anatomical structure formation involved in morphogenesis [GO:0048646]; androgen metabolic process [GO:0008209]; angiogenesis [GO:0001525]; animal organ formation [GO:0048645]; anterior/posterior pattern specification [GO:0009952]; apoptotic signaling pathway [GO:0097190]; artery development [GO:0060840]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; blood coagulation [GO:0007596]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bud outgrowth involved in lung branching [GO:0060447]; camera-type eye development [GO:0043010]; canonical Wnt signaling pathway [GO:0060070]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell development [GO:0048468]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cell proliferation in external granule layer [GO:0021924]; cell-cell signaling [GO:0007267]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; cerebellar granule cell precursor proliferation [GO:0021930]; commissural neuron axon guidance [GO:0071679]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; determination of left/right symmetry [GO:0007368]; developmental growth [GO:0048589]; digestive tract mesoderm development [GO:0007502]; digestive tract morphogenesis [GO:0048546]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic morphogenesis [GO:0048598]; embryonic organ development [GO:0048568]; embryonic skeletal system development [GO:0048706]; endocytosis [GO:0006897]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; epithelial-mesenchymal cell signaling [GO:0060684]; epithelial-mesenchymal signaling involved in prostate gland development [GO:0060738]; establishment of cell polarity [GO:0030010]; forebrain development [GO:0030900]; forebrain regionalization [GO:0021871]; formation of anatomical boundary [GO:0048859]; fungiform papilla development [GO:0061196]; fungiform papilla formation [GO:0061198]; fungiform papilla morphogenesis [GO:0061197]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; inner ear development [GO:0048839]; intein-mediated protein splicing [GO:0016539]; intermediate filament organization [GO:0045109]; kidney development [GO:0001822]; left lung development [GO:0060459]; limb bud formation [GO:0060174]; limb development [GO:0060173]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung lobe morphogenesis [GO:0060463]; lung morphogenesis [GO:0060425]; lung-associated mesenchyme development [GO:0060484]; lymphoid progenitor cell differentiation [GO:0002320]; male genitalia development [GO:0030539]; male genitalia morphogenesis [GO:0048808]; mesenchymal cell proliferation [GO:0010463]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal smoothened signaling pathway involved in prostate gland development [GO:0060783]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephros development [GO:0001656]; midbrain development [GO:0030901]; myoblast differentiation [GO:0045445]; myotube differentiation [GO:0014902]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of gene expression [GO:0010629]; negative regulation of kidney smooth muscle cell differentiation [GO:2000357]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of neuron death [GO:1901215]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of ureter smooth muscle cell differentiation [GO:2000062]; negative regulation of Wnt signaling pathway [GO:0030178]; negative thymic T cell selection [GO:0045060]; neural crest cell migration [GO:0001755]; neural tube formation [GO:0001841]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; odontogenesis [GO:0042476]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; osteoblast development [GO:0002076]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; polarity specification of anterior/posterior axis [GO:0009949]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of gene expression [GO:0010628]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of kidney smooth muscle cell differentiation [GO:2000358]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mesenchymal cell proliferation involved in ureter development [GO:2000729]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neurotrophin production [GO:0032901]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; positive regulation of penile erection [GO:0060406]; positive regulation of photoreceptor cell differentiation [GO:0046534]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sclerotome development [GO:0061189]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ureter smooth muscle cell differentiation [GO:2000063]; positive regulation of Wnt signaling pathway [GO:0030177]; positive thymic T cell selection [GO:0045059]; primary prostatic bud elongation [GO:0060516]; prostate epithelial cord elongation [GO:0060523]; prostate gland development [GO:0030850]; protein localization to nucleus [GO:0034504]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of gene expression [GO:0010468]; regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782]; regulation of odontogenesis [GO:0042481]; regulation of prostatic bud formation [GO:0060685]; regulation of protein localization to nucleus [GO:1900180]; regulation of proteolysis [GO:0030162]; regulation of transcription, DNA-templated [GO:0006355]; respiratory tube development [GO:0030323]; response to axon injury [GO:0048678]; response to ethanol [GO:0045471]; right lung development [GO:0060458]; roof of mouth development [GO:0060021]; salivary gland cavitation [GO:0060662]; signal transduction [GO:0007165]; skin development [GO:0043588]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; somite development [GO:0061053]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord motor neuron differentiation [GO:0021522]; stem cell development [GO:0048864]; striated muscle cell differentiation [GO:0051146]; striated muscle tissue development [GO:0014706]; T cell differentiation in thymus [GO:0033077]; telencephalon regionalization [GO:0021978]; thalamus development [GO:0021794]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue development [GO:0043586]; tongue morphogenesis [GO:0043587]; trachea development [GO:0060438]; trachea morphogenesis [GO:0060439]; tracheoesophageal septum formation [GO:1905327]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; ventral spinal cord interneuron specification [GO:0021521]; zona limitans intrathalamica formation [GO:0022006]	cell wall organization [GO:0071555]	anatomical structure development [GO:0048856]; anatomical structure formation involved in morphogenesis [GO:0048646]; androgen metabolic process [GO:0008209]; angiogenesis [GO:0001525]; animal organ formation [GO:0048645]; anterior/posterior pattern specification [GO:0009952]; apoptotic signaling pathway [GO:0097190]; artery development [GO:0060840]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; blood coagulation [GO:0007596]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bud outgrowth involved in lung branching [GO:0060447]; camera-type eye development [GO:0043010]; canonical Wnt signaling pathway [GO:0060070]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell-cell signaling [GO:0007267]; cell development [GO:0048468]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cell proliferation in external granule layer [GO:0021924]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; cerebellar granule cell precursor proliferation [GO:0021930]; commissural neuron axon guidance [GO:0071679]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; determination of left/right symmetry [GO:0007368]; developmental growth [GO:0048589]; digestive tract mesoderm development [GO:0007502]; digestive tract morphogenesis [GO:0048546]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic morphogenesis [GO:0048598]; embryonic organ development [GO:0048568]; embryonic skeletal system development [GO:0048706]; endocytosis [GO:0006897]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial-mesenchymal cell signaling [GO:0060684]; epithelial-mesenchymal signaling involved in prostate gland development [GO:0060738]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of cell polarity [GO:0030010]; forebrain development [GO:0030900]; forebrain regionalization [GO:0021871]; formation of anatomical boundary [GO:0048859]; fungiform papilla development [GO:0061196]; fungiform papilla formation [GO:0061198]; fungiform papilla morphogenesis [GO:0061197]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; inner ear development [GO:0048839]; intein-mediated protein splicing [GO:0016539]; intermediate filament organization [GO:0045109]; kidney development [GO:0001822]; left lung development [GO:0060459]; limb bud formation [GO:0060174]; limb development [GO:0060173]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung lobe morphogenesis [GO:0060463]; lung morphogenesis [GO:0060425]; lymphoid progenitor cell differentiation [GO:0002320]; male genitalia development [GO:0030539]; male genitalia morphogenesis [GO:0048808]; mesenchymal cell proliferation [GO:0010463]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal smoothened signaling pathway involved in prostate gland development [GO:0060783]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephros development [GO:0001656]; midbrain development [GO:0030901]; myoblast differentiation [GO:0045445]; myotube differentiation [GO:0014902]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of gene expression [GO:0010629]; negative regulation of kidney smooth muscle cell differentiation [GO:2000357]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of neuron death [GO:1901215]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of ureter smooth muscle cell differentiation [GO:2000062]; negative regulation of Wnt signaling pathway [GO:0030178]; negative thymic T cell selection [GO:0045060]; neural crest cell migration [GO:0001755]; neural tube formation [GO:0001841]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; odontogenesis [GO:0042476]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; osteoblast development [GO:0002076]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; polarity specification of anterior/posterior axis [GO:0009949]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of gene expression [GO:0010628]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of kidney smooth muscle cell differentiation [GO:2000358]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mesenchymal cell proliferation involved in ureter development [GO:2000729]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neurotrophin production [GO:0032901]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; positive regulation of penile erection [GO:0060406]; positive regulation of photoreceptor cell differentiation [GO:0046534]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sclerotome development [GO:0061189]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ureter smooth muscle cell differentiation [GO:2000063]; positive regulation of Wnt signaling pathway [GO:0030177]; positive thymic T cell selection [GO:0045059]; primary prostatic bud elongation [GO:0060516]; prostate epithelial cord elongation [GO:0060523]; prostate gland development [GO:0030850]; protein localization to nucleus [GO:0034504]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of gene expression [GO:0010468]; regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782]; regulation of odontogenesis [GO:0042481]; regulation of prostatic bud formation [GO:0060685]; regulation of protein localization to nucleus [GO:1900180]; regulation of proteolysis [GO:0030162]; regulation of transcription, DNA-templated [GO:0006355]; respiratory tube development [GO:0030323]; response to axon injury [GO:0048678]; response to ethanol [GO:0045471]; right lung development [GO:0060458]; roof of mouth development [GO:0060021]; salivary gland cavitation [GO:0060662]; signal transduction [GO:0007165]; skin development [GO:0043588]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; somite development [GO:0061053]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord motor neuron differentiation [GO:0021522]; stem cell development [GO:0048864]; striated muscle cell differentiation [GO:0051146]; striated muscle tissue development [GO:0014706]; T cell differentiation in thymus [GO:0033077]; telencephalon regionalization [GO:0021978]; thalamus development [GO:0021794]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue development [GO:0043586]; tongue morphogenesis [GO:0043587]; trachea development [GO:0060438]; trachea morphogenesis [GO:0060439]; tracheoesophageal septum formation [GO:1905327]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; ventral spinal cord interneuron specification [GO:0021521]; zona limitans intrathalamica formation [GO:0022006]	extracellular region [GO:0005576]	axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]; transport vesicle [GO:0030133]	metal ion binding [GO:0046872]; zinc D-Ala-D-Ala carboxypeptidase activity [GO:0009046]	calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; laminin-1 binding [GO:0043237]; patched binding [GO:0005113]; zinc ion binding [GO:0008270]
d1lc5a__d2ay1a___1			Proteobacteria	Proteobacteria	pyridoxal phosphate binding [GO:0030170]; threonine-phosphate decarboxylase activity [GO:0048472]; cobalamin biosynthetic process [GO:0009236]	cytoplasm [GO:0005737]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]; aromatic amino acid family biosynthetic process [GO:0009073]	cobalamin biosynthetic process [GO:0009236]	aromatic amino acid family biosynthetic process [GO:0009073]		cytoplasm [GO:0005737]	pyridoxal phosphate binding [GO:0030170]; threonine-phosphate decarboxylase activity [GO:0048472]	L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]
d1lcfa2_d3fgsa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d1lcfa2_d4mmpa1__1	Metazoa		Chordata		cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]		antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	
d1lcja__d4eiha___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cytosol [GO:0005829]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein kinase activity [GO:0004672]; protein tyrosine kinase activity [GO:0004713]; cell adhesion [GO:0007155]; cellular protein modification process [GO:0006464]; cellular response to retinoic acid [GO:0071300]; exploration behavior [GO:0035640]; negative regulation of Rho protein signal transduction [GO:0035024]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of neuron projection development [GO:0010976]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of phospholipase C activity [GO:0010863]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell adhesion [GO:0007155]; cellular protein modification process [GO:0006464]; cellular response to retinoic acid [GO:0071300]; exploration behavior [GO:0035640]; negative regulation of Rho protein signal transduction [GO:0035024]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of neuron projection development [GO:0010976]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of phospholipase C activity [GO:0010863]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cytosol [GO:0005829]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein kinase activity [GO:0004672]; protein tyrosine kinase activity [GO:0004713]
d1lcla__d1v6nc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; carbohydrate binding [GO:0030246]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; identical protein binding [GO:0042802]; multicellular organism development [GO:0007275]; regulation of activated T cell proliferation [GO:0046006]; regulation of T cell anergy [GO:0002667]; regulation of T cell cytokine production [GO:0002724]; T cell apoptotic process [GO:0070231]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	multicellular organism development [GO:0007275]; regulation of activated T cell proliferation [GO:0046006]; regulation of T cell anergy [GO:0002667]; regulation of T cell cytokine production [GO:0002724]; T cell apoptotic process [GO:0070231]		collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]		carbohydrate binding [GO:0030246]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; identical protein binding [GO:0042802]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1lcoa2_d3lf5b___1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; perinuclear region of cytoplasm [GO:0048471]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; bicarbonate transport [GO:0015701]; cell development [GO:0048468]; detection of oxygen [GO:0003032]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; insulin secretion [GO:0030073]; oxidation-reduction process [GO:0055114]; response to antibiotic [GO:0046677]; superoxide metabolic process [GO:0006801]	lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	bicarbonate transport [GO:0015701]; cell development [GO:0048468]; detection of oxygen [GO:0003032]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; insulin secretion [GO:0030073]; oxidation-reduction process [GO:0055114]; response to antibiotic [GO:0046677]; superoxide metabolic process [GO:0006801]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; perinuclear region of cytoplasm [GO:0048471]	heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d1lcub1_d4jhda2__1	Metazoa	Metazoa	Chordata	Arthropoda	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]
d1lcub2_d4m7xa1__1	Metazoa		Chordata	Firmicutes	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	coenzyme A biosynthetic process [GO:0015937]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cytoplasm [GO:0005737]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d1lcwa__d3vgwd___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]; antibacterial humoral response [GO:0019731]		antibacterial humoral response [GO:0019731]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1lczb__d2of8a1__1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1ld8a__d1tnoi___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]; protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]; protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1ld9b__d4pj7g1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ld9e__d1lo0y1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1lddc__d1iuya___1	Fungi	Metazoa	Ascomycota	Chordata	anaphase-promoting complex [GO:0005680]; cytoplasm [GO:0005737]; ubiquitin protein ligase binding [GO:0031625]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; exit from mitosis [GO:0010458]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; protein ubiquitination [GO:0016567]	cell [GO:0005623]; centrosome [GO:0005813]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; polar microtubule [GO:0005827]; sperm flagellum [GO:0036126]; spindle pole [GO:0000922]; cyclin binding [GO:0030332]; Notch binding [GO:0005112]; POZ domain binding [GO:0031208]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cell projection organization [GO:0030030]; COPII vesicle coating [GO:0048208]; embryonic cleavage [GO:0040016]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibroblast apoptotic process [GO:0044346]; gastrulation [GO:0007369]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; liver morphogenesis [GO:0072576]; mitotic cell cycle [GO:0000278]; mitotic metaphase plate congression [GO:0007080]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear protein quality control by the ubiquitin-proteasome system [GO:0071630]; positive regulation of cytokinesis [GO:0032467]; positive regulation of mitotic cell cycle phase transition [GO:1901992]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell division [GO:0017145]; stress fiber assembly [GO:0043149]; trophectodermal cellular morphogenesis [GO:0001831]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; exit from mitosis [GO:0010458]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; protein ubiquitination [GO:0016567]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cell projection organization [GO:0030030]; COPII vesicle coating [GO:0048208]; embryonic cleavage [GO:0040016]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibroblast apoptotic process [GO:0044346]; gastrulation [GO:0007369]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; liver morphogenesis [GO:0072576]; mitotic cell cycle [GO:0000278]; mitotic metaphase plate congression [GO:0007080]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear protein quality control by the ubiquitin-proteasome system [GO:0071630]; positive regulation of cytokinesis [GO:0032467]; positive regulation of mitotic cell cycle phase transition [GO:1901992]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell division [GO:0017145]; stress fiber assembly [GO:0043149]; trophectodermal cellular morphogenesis [GO:0001831]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	anaphase-promoting complex [GO:0005680]; cytoplasm [GO:0005737]	cell [GO:0005623]; centrosome [GO:0005813]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; polar microtubule [GO:0005827]; sperm flagellum [GO:0036126]; spindle pole [GO:0000922]	ubiquitin protein ligase binding [GO:0031625]	cyclin binding [GO:0030332]; Notch binding [GO:0005112]; POZ domain binding [GO:0031208]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]
d1ldea2_d1ju9a2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]	cytosol [GO:0005829]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1ldeb2_d4zd6f___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	metal ion binding [GO:0046872]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1lded2_d4egfc___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	L-xylulose reductase (NAD+) activity [GO:0044105]; L-xylulose reductase (NADP+) activity [GO:0050038]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	L-xylulose reductase (NAD+) activity [GO:0044105]; L-xylulose reductase (NADP+) activity [GO:0050038]
d1ldga1_d4wlvb1__1		Metazoa	Apicomplexa	Chordata	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d1ldma1_d1j4aa1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]
d1ldma2_d1sova2__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d1ldna1_d4jp3a___1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]	nucleotide binding [GO:0000166]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]
d1ldnc2_d2zqzf2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]
d1ldnd1_d1up6d1__1			Firmicutes	Thermotogae	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d1ldnh1_d4l75f1__1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	glycolytic process [GO:0006096]	potassium ion transport [GO:0006813]	cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1ldnh2_d1smkf2__1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	glyoxysome [GO:0009514]	L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-malate dehydrogenase activity [GO:0030060]
d1ldoa__d1wbih___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]; antibacterial humoral response [GO:0019731]	extracellular region [GO:0005576]; biotin binding [GO:0009374]; biotin transport [GO:0015878]	antibacterial humoral response [GO:0019731]	biotin transport [GO:0015878]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1ldtt__d6esta___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1ldyb2_d2fzwb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]
d1le5a1_d2as5n1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	nuclear chromatin [GO:0000790]; androgen receptor binding [GO:0050681]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; camera-type eye development [GO:0043010]; caudate nucleus development [GO:0021757]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; innate vocalization behavior [GO:0098582]; lung alveolus development [GO:0048286]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of mesenchymal cell proliferation [GO:0002053]; post-embryonic development [GO:0009791]; putamen development [GO:0021758]; response to testosterone [GO:0033574]; righting reflex [GO:0060013]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; vocal learning [GO:0042297]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	camera-type eye development [GO:0043010]; caudate nucleus development [GO:0021757]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; innate vocalization behavior [GO:0098582]; lung alveolus development [GO:0048286]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of mesenchymal cell proliferation [GO:0002053]; post-embryonic development [GO:0009791]; putamen development [GO:0021758]; response to testosterone [GO:0033574]; righting reflex [GO:0060013]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; vocal learning [GO:0042297]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nuclear chromatin [GO:0000790]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	androgen receptor binding [GO:0050681]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]
d1le5b1_d1eo5a1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1le5b2_d1owrn2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1le5b2_d3vd1b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1le5f1_d1ttua1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; cell fate specification [GO:0001708]; dauer exit [GO:0043054]; germ-line stem cell division [GO:0042078]; nematode larval development [GO:0002119]; Notch signaling pathway [GO:0007219]; oviposition [GO:0018991]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vulval development [GO:0040026]; regulation of cell fate specification [GO:0042659]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cell fate specification [GO:0001708]; dauer exit [GO:0043054]; germ-line stem cell division [GO:0042078]; nematode larval development [GO:0002119]; Notch signaling pathway [GO:0007219]; oviposition [GO:0018991]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vulval development [GO:0040026]; regulation of cell fate specification [GO:0042659]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]
d1le5f2_d4a63k1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1le6b__d1p7oc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipase activity [GO:0004620]; arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; axon guidance [GO:0007411]; cellular response to leukemia inhibitory factor [GO:1990830]; cholesterol homeostasis [GO:0042632]; lipid catabolic process [GO:0016042]; lysophospholipid transport [GO:0051977]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of prostaglandin secretion [GO:0032308]; regulation of macrophage activation [GO:0043030]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; axon guidance [GO:0007411]; cellular response to leukemia inhibitory factor [GO:1990830]; cholesterol homeostasis [GO:0042632]; lipid catabolic process [GO:0016042]; lysophospholipid transport [GO:0051977]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of prostaglandin secretion [GO:0032308]; regulation of macrophage activation [GO:0043030]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipase activity [GO:0004620]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1le9a1_d1a3qb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	Bcl3/NF-kappaB2 complex [GO:0033257]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; aging [GO:0007568]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; rhythmic process [GO:0048511]; spleen development [GO:0048536]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; rhythmic process [GO:0048511]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	Bcl3/NF-kappaB2 complex [GO:0033257]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]
d1le9a1_d2c9pa___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	periplasmic space [GO:0042597]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	copper ion binding [GO:0005507]
d1le9b2_d1p7ho2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1le9b2_d4kvpa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1le9e1_d5fjqc___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1le9e2_d1imhd2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cytokine production [GO:0001816]; excretion [GO:0007588]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; response to osmotic stress [GO:0006970]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cytokine production [GO:0001816]; excretion [GO:0007588]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; response to osmotic stress [GO:0006970]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1le9f1_d1c7ta1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	periplasmic space [GO:0042597]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]
d1leba__d2hdca___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]; transcription, DNA-templated [GO:0006351]	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; sequence-specific DNA binding [GO:0043565]; anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; in utero embryonic development [GO:0001701]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]; transcription, DNA-templated [GO:0006351]	anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; in utero embryonic development [GO:0001701]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; sequence-specific DNA binding [GO:0043565]
d1leda__d2zhma___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]
d1legb__d3tvmd1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1leha1_d1llqa1__1		Metazoa	Firmicutes	Nematoda (roundworms)	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	mitochondrial matrix [GO:0005759]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]	cellular amino acid metabolic process [GO:0006520]			mitochondrial matrix [GO:0005759]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]
d1leha2_d4fosa1__1			Firmicutes	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1lehb2_d5gudf1__1			Firmicutes	Actinobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]			nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1leib1_d1z0ma1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; fatty acid biosynthetic process [GO:0006633]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; regulation of catalytic activity [GO:0050790]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	fatty acid biosynthetic process [GO:0006633]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; regulation of catalytic activity [GO:0050790]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]
d1leib2_d2vuka___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1lem.1_d1qu0b___1	Viridiplantae	Metazoa	Streptophyta	Chordata	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]; carbohydrate mediated signaling [GO:0009756]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	carbohydrate mediated signaling [GO:0009756]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]		basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]	signaling receptor binding [GO:0005102]
d1leoa__d3ztsf___1				Aquificae	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1les.1_d1w6nb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]; carbohydrate mediated signaling [GO:0009756]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	carbohydrate mediated signaling [GO:0009756]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d1les.2_d4wv8b___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]; carbohydrate mediated signaling [GO:0009756]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate mediated signaling [GO:0009756]				calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1lf2a__d1htgb___1			Apicomplexa		vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1lf3a__d2avsa___1			Apicomplexa		vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1lf6b1_d5gxza1__1			Firmicutes	Firmicutes	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; polysaccharide metabolic process [GO:0005976]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	polysaccharide metabolic process [GO:0005976]	polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1lf8c__d4flba___1	Metazoa	Metazoa	Chordata	Chordata	early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]; ADP-ribosylation factor binding [GO:0030306]; ubiquitin binding [GO:0043130]; cellular protein metabolic process [GO:0044267]; endocytic recycling [GO:0032456]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; negative regulation of amyloid-beta formation [GO:1902430]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein localization to cell surface [GO:0034394]; protein localization to lysosome [GO:0061462]; regulation of protein stability [GO:0031647]	nucleoplasm [GO:0005654]; RNA polymerase II, holoenzyme [GO:0016591]; RNA polymerase II complex binding [GO:0000993]; mRNA 3'-end processing [GO:0031124]; snRNA transcription by RNA polymerase II [GO:0042795]	cellular protein metabolic process [GO:0044267]; endocytic recycling [GO:0032456]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; negative regulation of amyloid-beta formation [GO:1902430]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein localization to cell surface [GO:0034394]; protein localization to lysosome [GO:0061462]; regulation of protein stability [GO:0031647]	mRNA 3'-end processing [GO:0031124]; snRNA transcription by RNA polymerase II [GO:0042795]	early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]	nucleoplasm [GO:0005654]; RNA polymerase II, holoenzyme [GO:0016591]	ADP-ribosylation factor binding [GO:0030306]; ubiquitin binding [GO:0043130]	RNA polymerase II complex binding [GO:0000993]
d1lf8d1_d3zykb1__1	Metazoa	Metazoa	Chordata	Chordata	early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]; ADP-ribosylation factor binding [GO:0030306]; ubiquitin binding [GO:0043130]; cellular protein metabolic process [GO:0044267]; endocytic recycling [GO:0032456]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; negative regulation of amyloid-beta formation [GO:1902430]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein localization to cell surface [GO:0034394]; protein localization to lysosome [GO:0061462]; regulation of protein stability [GO:0031647]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]; 1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]; axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	cellular protein metabolic process [GO:0044267]; endocytic recycling [GO:0032456]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; negative regulation of amyloid-beta formation [GO:1902430]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein localization to cell surface [GO:0034394]; protein localization to lysosome [GO:0061462]; regulation of protein stability [GO:0031647]	axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]	ADP-ribosylation factor binding [GO:0030306]; ubiquitin binding [GO:0043130]	1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]
d1lf9b2_d1jyva4__1			Firmicutes	Proteobacteria	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; polysaccharide metabolic process [GO:0005976]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide metabolic process [GO:0005976]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1lfdd__d1crra___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1lfia1_d1ovta1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]
d1lfia2_d1aiva1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]
d1lfja__d1aype___1		Metazoa		Chordata		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]; antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]		antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]		calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]
d1lfld__d2uumq___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1lfma__d1h31a1__1	Metazoa		Chordata	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1lfqb__d1ithb___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1lfva__d1ha7c___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1lg1a2_d1nwsb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; endochitinase activity [GO:0008843]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; polysaccharide catabolic process [GO:0000272]; polysaccharide digestion [GO:0044245]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; specific granule lumen [GO:0035580]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; extracellular matrix structural constituent [GO:0005201]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; neutrophil degranulation [GO:0043312]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	chitin catabolic process [GO:0006032]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; polysaccharide catabolic process [GO:0000272]; polysaccharide digestion [GO:0044245]; response to bacterium [GO:0009617]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; neutrophil degranulation [GO:0043312]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; specific granule lumen [GO:0035580]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]; endochitinase activity [GO:0008843]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; extracellular matrix structural constituent [GO:0005201]
d1lg2a2_d1hjva2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; endochitinase activity [GO:0008843]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; polysaccharide catabolic process [GO:0000272]; polysaccharide digestion [GO:0044245]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; specific granule lumen [GO:0035580]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; extracellular matrix structural constituent [GO:0005201]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; neutrophil degranulation [GO:0043312]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	chitin catabolic process [GO:0006032]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; polysaccharide catabolic process [GO:0000272]; polysaccharide digestion [GO:0044245]; response to bacterium [GO:0009617]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; neutrophil degranulation [GO:0043312]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; specific granule lumen [GO:0035580]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]; endochitinase activity [GO:0008843]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; extracellular matrix structural constituent [GO:0005201]
d1lgb.1_d1n3oa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1lgb.1_d2exha1__1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	carbohydrate metabolic process [GO:0005975]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1lgnc__d1utwe2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	
d1lgpa__d1j4oa___1	Metazoa	Fungi	Chordata	Ascomycota	nucleus [GO:0005634]; PML body [GO:0016605]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; modification-dependent protein catabolic process [GO:0019941]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; modification-dependent protein catabolic process [GO:0019941]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511]	deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	nucleus [GO:0005634]; PML body [GO:0016605]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]
d1lgqb__d1gxcg___1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; PML body [GO:0016605]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; modification-dependent protein catabolic process [GO:0019941]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625]; cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic DNA damage checkpoint [GO:0044773]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; replicative senescence [GO:0090399]; response to glycoside [GO:1903416]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]	cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; modification-dependent protein catabolic process [GO:0019941]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic DNA damage checkpoint [GO:0044773]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; replicative senescence [GO:0090399]; response to glycoside [GO:1903416]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]	nucleus [GO:0005634]; PML body [GO:0016605]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625]
d1lgua__d3a3rx___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1lgvb2_d4oclf___1	Metazoa	Fungi	Chordata	Ascomycota		proteasome complex [GO:0000502]; proteasome regulatory particle, lid subcomplex [GO:0008541]; proteasome storage granule [GO:0034515]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; ubiquitin-dependent protein catabolic process [GO:0006511]		proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; ubiquitin-dependent protein catabolic process [GO:0006511]		proteasome complex [GO:0000502]; proteasome regulatory particle, lid subcomplex [GO:0008541]; proteasome storage granule [GO:0034515]		
d1lgya__d4zv7a___1	Fungi	Fungi	Mucoromycota	Basidiomycota	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular space [GO:0005615]		metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	triglyceride lipase activity [GO:0004806]
d1lhd.1_d3snea___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1lhf.1_d1kxda___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]
d1lhia__d4mcka1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; chitin binding [GO:0008061]; endochitinase activity [GO:0008843]; amino sugar metabolic process [GO:0006040]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; polysaccharide catabolic process [GO:0000272]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	amino sugar metabolic process [GO:0006040]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; polysaccharide catabolic process [GO:0000272]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	chitin binding [GO:0008061]; endochitinase activity [GO:0008843]
d1lhka__d3cdob___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lhrb__d5byda1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]; pyridoxal 5'-phosphate salvage [GO:0009443]	cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]	pyridoxal 5'-phosphate salvage [GO:0009443]	D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d1lhta__d3wfxa1__1	Metazoa		Chordata	Verrucomicrobia	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]		response to nitrosative stress [GO:0051409]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1lhza2_d5u17g2__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1li1e1_d1t60w2__1	Metazoa	Metazoa	Chordata	Chordata	collagen type IV trimer [GO:0005587]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; aging [GO:0007568]; angiogenesis [GO:0001525]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; negative regulation of angiogenesis [GO:0016525]; response to activity [GO:0014823]; transcription, DNA-templated [GO:0006351]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	aging [GO:0007568]; angiogenesis [GO:0001525]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; negative regulation of angiogenesis [GO:0016525]; response to activity [GO:0014823]; transcription, DNA-templated [GO:0006351]		collagen-containing extracellular matrix [GO:0062023]; collagen type IV trimer [GO:0005587]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]	extracellular matrix structural constituent [GO:0005201]
d1li1f1_d1t60b1__1	Metazoa	Metazoa	Chordata	Chordata	collagen type IV trimer [GO:0005587]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; aging [GO:0007568]; angiogenesis [GO:0001525]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; negative regulation of angiogenesis [GO:0016525]; response to activity [GO:0014823]; transcription, DNA-templated [GO:0006351]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	aging [GO:0007568]; angiogenesis [GO:0001525]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; negative regulation of angiogenesis [GO:0016525]; response to activity [GO:0014823]; transcription, DNA-templated [GO:0006351]		collagen-containing extracellular matrix [GO:0062023]; collagen type IV trimer [GO:0005587]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]	extracellular matrix structural constituent [GO:0005201]
d1li2a__d1ky1a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1li2a__d4msta___1		Viridiplantae		Streptophyta	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]	host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d1li3a__d2b6ta___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1li4a1_d2ewdb3__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]; sulfur amino acid metabolic process [GO:0000096]		chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]; sulfur amino acid metabolic process [GO:0000096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]		adenosylhomocysteinase activity [GO:0004013]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	
d1li5b1_d4zt6b2__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; cysteine-tRNA ligase activity [GO:0004817]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cysteinyl-tRNA aminoacylation [GO:0006423]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	cysteinyl-tRNA aminoacylation [GO:0006423]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; cysteine-tRNA ligase activity [GO:0004817]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]
d1li7a1_d1qqta1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; cysteine-tRNA ligase activity [GO:0004817]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cysteinyl-tRNA aminoacylation [GO:0006423]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; methionyl-tRNA aminoacylation [GO:0006431]	cysteinyl-tRNA aminoacylation [GO:0006423]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; cysteine-tRNA ligase activity [GO:0004817]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1liaa__d2uumb___1			Rhodophyta	Cyanobacteria	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	phycobilisome [GO:0030089]		
d1liab__d1c7bc___1		Metazoa	Rhodophyta	Chordata	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1lial__d2bv8m___1			Rhodophyta	Rhodophyta	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]		
d1liba__d4iawb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1lifa__d1gt5a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	extracellular region [GO:0005576]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	small molecule binding [GO:0036094]
d1lifa__d4ydaa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1lila2_d4u05a___1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1lilb2_d1q8mb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]; acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]
d1liua5_d1aqfd1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]		positive regulation of sprouting angiogenesis [GO:1903672]		cytoplasm [GO:0005737]; nucleus [GO:0005634]		ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1liuc6_d1pklg3__1						ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]						ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1liya6_d3qv7b2__1						ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]						ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1liyd6_d1liwb5__1												
d1lj3b__d1qtva___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lj4b__d4kpmd___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; dormancy exit of symbiont in host [GO:0085016]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	dormancy exit of symbiont in host [GO:0085016]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	hydrolase activity [GO:0016787]
d1lj7b__d1enxb1__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	endo-1,4-beta-xylanase activity [GO:0031176]
d1lj7j__d3wuda___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	carbohydrate binding [GO:0030246]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	carbohydrate binding [GO:0030246]
d1lj9a__d1jgsa___1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; cellular response to antibiotic [GO:0071236]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to heat [GO:0009408]		cellular response to antibiotic [GO:0071236]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to heat [GO:0009408]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]
d1ljga__d1gf8a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ljgb__d149la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ljoa1_d1vu3h___1			Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]			
d1ljra1_d4pnff2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1ljrb2_d4kb3b___1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]	glutathione transferase activity [GO:0004364]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1ljtc__d3mjzk___1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	
d1ljwa__d1ufja___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1lk0b__d1u2pa___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]	extracellular region [GO:0005576]; host cell endosome [GO:0044174]; plasma membrane [GO:0005886]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein dephosphorylation [GO:0006470]	response to arsenic-containing substance [GO:0046685]	negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; host cell endosome [GO:0044174]; plasma membrane [GO:0005886]	arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d1lk2a2_d2av7a2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1lk3h1_d1s7ud1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]; aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1lk3i2_d3cplb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]; aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1lk3l2_d2mcg12__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]; aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]	antigen binding [GO:0003823]
d1lk3l2_d3mlyl1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]; aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]		aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]	
d1lk3m2_d1g9nc2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]; aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1lk9a__d3usfa___1	Viridiplantae		Streptophyta	Cyanobacteria	vacuole [GO:0005773]; alliin lyase activity [GO:0047654]	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]		chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	vacuole [GO:0005773]	cytoplasm [GO:0005737]	alliin lyase activity [GO:0047654]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1lk9b__d1j32a___1	Viridiplantae		Streptophyta	Cyanobacteria	vacuole [GO:0005773]; alliin lyase activity [GO:0047654]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]		biosynthetic process [GO:0009058]	vacuole [GO:0005773]		alliin lyase activity [GO:0047654]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1lkba__d3e91b___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1lkma1_d5jkld___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cytoplasm [GO:0005737]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1lkna__d1dgrb___1		Viridiplantae	Thermotogae	Streptophyta		protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]		protein homotrimerization [GO:0070207]		protein-containing complex [GO:0032991]		identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]
d1lksa__d1cu5a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lkyf__d4mhva___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription by RNA polymerase II [GO:0006357]; vitellogenesis [GO:0007296]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; glucocorticoid receptor binding [GO:0035259]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; cell differentiation [GO:0030154]; ectodermal cell fate commitment [GO:0001712]; mesoderm development [GO:0007498]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; primitive streak formation [GO:0090009]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]	cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription by RNA polymerase II [GO:0006357]; vitellogenesis [GO:0007296]	cell differentiation [GO:0030154]; ectodermal cell fate commitment [GO:0001712]; mesoderm development [GO:0007498]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primitive streak formation [GO:0090009]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; glucocorticoid receptor binding [GO:0035259]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d1ll6d2_d1wnob2__1	Fungi	Fungi	Ascomycota	Ascomycota	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d1llda1_d1zemb___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1llfa__d4ke9c___1	Fungi		Ascomycota	Firmicutes	triglyceride lipase activity [GO:0004806]	acylglycerol lipase activity [GO:0047372]					triglyceride lipase activity [GO:0004806]	acylglycerol lipase activity [GO:0047372]
d1lloa__d3pzma___1	Viridiplantae		Streptophyta	Thermotogae	vacuole [GO:0005773]; chitinase activity [GO:0004568]; lysozyme activity [GO:0003796]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	vacuole [GO:0005773]		chitinase activity [GO:0004568]; lysozyme activity [GO:0003796]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]
d1llrf__d1eefg___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		toxin activity [GO:0090729]
d1llrg__d1bosg___1			Proteobacteria		extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		toxin activity [GO:0090729]
d1llua2_d1n9gf2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]	mitochondrion [GO:0005739]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]
d1llua2_d4zd6d___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]			cytoplasm [GO:0005737]		alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1llud2_d4nbwc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]			cytoplasm [GO:0005737]		alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1llue2_d2yv1a1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]		nucleoside triphosphate biosynthetic process [GO:0009142]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d1lluf2_d1hldb2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1lluf2_d4kued1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]		fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]		alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]
d1lm3b__d3c63c___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1lmb3__d3g5gj___1				Proteobacteria	virion [GO:0019012]; core promoter binding [GO:0001047]; identical protein binding [GO:0042802]; latency-replication decision [GO:0098689]; maintenance of viral latency [GO:0019044]; negative regulation of transcription by competitive promoter binding [GO:0010944]; positive regulation of viral transcription [GO:0050434]	DNA binding [GO:0003677]	latency-replication decision [GO:0098689]; maintenance of viral latency [GO:0019044]; negative regulation of transcription by competitive promoter binding [GO:0010944]; positive regulation of viral transcription [GO:0050434]		virion [GO:0019012]		core promoter binding [GO:0001047]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]
d1lmca__d1qsba___1	Metazoa		Chordata		extracellular space [GO:0005615]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lmka2_d2fsec1__1		Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1lmkc1_d1itbb3__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]		cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]		interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]
d1lmkc1_d4hgkc1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]		antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1lmkc2_d1y0lb1__1												
d1lmkc2_d5f89b1__1												
d1lmke1_d1ed3d1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]		
d1lmke2_d3qxud___1												
d1lmkg1_d2eytb2__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1lmkg2_d1clzh1__1		Metazoa		Chordata		extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; immunoglobulin receptor binding [GO:0034987]				extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		immunoglobulin receptor binding [GO:0034987]
d1lmqa__d1l15a___1	Metazoa		Chordata		extracellular space [GO:0005615]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lmsa__d4ye1b___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1lmta__d4i7la1__1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lmta__d5v4ga___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1lmza__d2ofkb___1			Proteobacteria	Proteobacteria	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	base-excision repair [GO:0006284]	base-excision repair [GO:0006284]			DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]
d1ln4a1_d1jo0b___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; preribosome binding [GO:1990275]; RNA binding [GO:0003723]; ribosomal large subunit assembly [GO:0000027]; ribosomal small subunit assembly [GO:0000028]; rRNA 5'-end processing [GO:0000967]	RNA binding [GO:0003723]	ribosomal large subunit assembly [GO:0000027]; ribosomal small subunit assembly [GO:0000028]; rRNA 5'-end processing [GO:0000967]		cytosol [GO:0005829]		preribosome binding [GO:1990275]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d1lnbe__d5uuca___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1lnfe__d3b8zb___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]		defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]
d1lnia__d1q9ec___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1lnib__d1ynvx___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1lnqb4_d2bkna2__1			Euryarchaeota	Euryarchaeota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	cation transmembrane transporter activity [GO:0008324]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	cation transmembrane transporter activity [GO:0008324]; metal ion binding [GO:0046872]
d1lnqf3_d1id1a___1			Euryarchaeota	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]	potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]
d1lnqf3_d1m6wa2__1		Metazoa	Euryarchaeota	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	potassium ion transport [GO:0006813]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]
d1lnua1_d3bgfl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1lnub1_d1pkqg1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	signaling receptor binding [GO:0005102]
d1lnuc1_d5grzg2__1	Metazoa		Chordata		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	
d1lnud2_d4huud1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1lnue2_d4pj7c1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1lnug1_d4hzll2__1	Metazoa		Chordata		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1lnxc__d4f77f___1			Crenarchaeota									
d1lo0h1_d1cfna1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1lo0h1_d1n59c1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1lo0l2_d1i9ry1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]; activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]
d1lo0y2_d3mugi2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1lo2l1_d5xjfc1__1	Metazoa	Metazoa	Chordata	Chordata		extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]		extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		
d1lo2l2_d4n1ee___1	Metazoa	Metazoa	Chordata	Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1lo2x1_d1nqba1__1	Metazoa		Chordata									
d1lo2x1_d4r7df2__1	Metazoa	Metazoa	Chordata	Chordata								
d1lo2x2_d1wwwy___1	Metazoa	Metazoa	Chordata	Chordata		axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]		cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]
d1lo2y1_d3nfsl2__1	Metazoa		Chordata									
d1lo2y2_d4apqc1__1	Metazoa	Metazoa	Chordata	Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1lo3h1_d3c6la1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1lo3h1_d5jdda2__1	Metazoa	Metazoa	Chordata	Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1lo3l1_d5hysl2__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1lo3l2_d2rcjm2__1	Metazoa	Metazoa	Chordata	Chordata								
d1lo3x1_d1tjgl1__1	Metazoa		Chordata			host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1lo3x1_d1wcba1__1	Metazoa		Chordata									
d1lo3x2_d2a1wl1__1	Metazoa	Metazoa	Chordata	Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d1lo3y1_d5i9qc2__1	Metazoa		Chordata			host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1lo4h1_d2ywza___1	Metazoa	Metazoa	Chordata	Chordata								
d1lo4l1_d4hzll1__1	Metazoa		Chordata			host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1lo4l2_d5xp1d1__1	Metazoa	Metazoa	Chordata	Chordata		blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d1lo5a1_d5bk5c1__1			Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]	
d1lo5d1_d1d1ib___1			Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1lo5d2_d3r2ta2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]	
d1lo6a__d1hb0b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]; serine-type endopeptidase activity [GO:0004252]; amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]	extracellular space [GO:0005615]	serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1lo6a__d2bdim___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]; serine-type endopeptidase activity [GO:0004252]; amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1lo8a__d2o6ta2__1			Proteobacteria	Proteobacteria	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	acyl-CoA hydrolase activity [GO:0047617]					4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	acyl-CoA hydrolase activity [GO:0047617]
d1loa.4_d1wblb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]					mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]
d1lob.1_d3nwkd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					mannose binding [GO:0005537]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1lob.1_d4jc1a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d1lob.2_d1qmo.4__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]	protein storage vacuole lumen [GO:0034495]; carbohydrate binding [GO:0030246]				protein storage vacuole lumen [GO:0034495]	mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]
d1loc.1_d3ap7a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d1loc.2_d1w2ua___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	mannose binding [GO:0005537]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]			mannose binding [GO:0005537]	cellulase activity [GO:0008810]
d1loc.4_d2ymzf1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]					mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d1lod.1_d1dlla1__1	Viridiplantae		Streptophyta	Firmicutes	mannose binding [GO:0005537]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	mannose binding [GO:0005537]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1lod.3_d1dq5a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					mannose binding [GO:0005537]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1lod.4_d4ixlb1__1	Viridiplantae		Streptophyta	Firmicutes	mannose binding [GO:0005537]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			mannose binding [GO:0005537]	endo-1,4-beta-xylanase activity [GO:0031176]
d1loe.1_d4avse___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	mannose binding [GO:0005537]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1lof.2_d1h8ve___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	mannose binding [GO:0005537]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]			mannose binding [GO:0005537]	cellulase activity [GO:0008810]
d1log.1_d5cela___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	mannose binding [GO:0005537]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	mannose binding [GO:0005537]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d1log.2_d2zmnc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]					mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]
d1loha1_d1cb8a1__1			Firmicutes	Bacteroidetes	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]
d1loha3_d4duxc5__1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	cell wall [GO:0005618]; extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1loja1_d1h64o___1			Euryarchaeota	Euryarchaeota	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]			
d1lojd1_d1i8fa___1			Euryarchaeota	Crenarchaeota	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]			
d1loje1_d1h64s___1			Euryarchaeota	Euryarchaeota	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]			
d1loje1_d1vu3c___1			Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]			
d1lojf1_d1h64q___1			Euryarchaeota	Euryarchaeota	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]			
d1lojf1_d4f77k___1			Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]			
d1lojh1_d4c92f___1		Fungi	Euryarchaeota	Ascomycota	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	Lsm1-7-Pat1 complex [GO:1990726]; nucleolus [GO:0005730]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]	mRNA splicing, via spliceosome [GO:0000398]	maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]	small nucleolar ribonucleoprotein complex [GO:0005732]	Lsm1-7-Pat1 complex [GO:1990726]; nucleolus [GO:0005730]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]		RNA binding [GO:0003723]
d1lojj1_d4c92d___1		Fungi	Euryarchaeota	Ascomycota	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	Lsm1-7-Pat1 complex [GO:1990726]; nucleolus [GO:0005730]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]	mRNA splicing, via spliceosome [GO:0000398]	maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]	small nucleolar ribonucleoprotein complex [GO:0005732]	Lsm1-7-Pat1 complex [GO:1990726]; nucleolus [GO:0005730]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]		RNA binding [GO:0003723]
d1lora__d5lhea___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	tryptophan biosynthetic process [GO:0000162]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	phosphoribosylanthranilate isomerase activity [GO:0004640]
d1losb__d4fiqb___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; pyridoxal phosphate biosynthetic process [GO:0042823]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal phosphate biosynthetic process [GO:0042823]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d1lota3_d1j78a2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]; vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]
d1loya__d1rcla___1	Fungi	Fungi	Ascomycota	Ascomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]		endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1lp9a1_d1a6ta1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1lp9a1_d3i02a2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1lp9b1_d5jw5l1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1lp9f2_d3w9dd2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1lp9h1_d5f3hd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]; cell development [GO:0048468]; cellular response to dexamethasone stimulus [GO:0071549]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of kinase activity [GO:0033673]; negative regulation of muscle hypertrophy [GO:0014741]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast proliferation [GO:2000818]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; negative regulation of skeletal muscle tissue growth [GO:0048632]; ovulation cycle process [GO:0022602]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; response to electrical stimulus [GO:0051602]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to gravity [GO:0009629]; response to heat [GO:0009408]; response to muscle activity [GO:0014850]; response to testosterone [GO:0033574]; skeletal muscle atrophy [GO:0014732]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell development [GO:0048468]; cellular response to dexamethasone stimulus [GO:0071549]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of kinase activity [GO:0033673]; negative regulation of muscle hypertrophy [GO:0014741]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast proliferation [GO:2000818]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; negative regulation of skeletal muscle tissue growth [GO:0048632]; ovulation cycle process [GO:0022602]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; response to electrical stimulus [GO:0051602]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to gravity [GO:0009629]; response to heat [GO:0009408]; response to muscle activity [GO:0014850]; response to testosterone [GO:0033574]; skeletal muscle atrophy [GO:0014732]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]
d1lp9l1_d1fvea1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1lp9l1_d5d4qb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1lp9l2_d4l4td2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1lp9m2_d1ad9b2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1lpab1_d2wxua2__1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; extracellular space [GO:0005615]; lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; intestinal cholesterol absorption [GO:0030299]; lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241]; lipid metabolic process [GO:0006629]; positive regulation of triglyceride lipase activity [GO:0061365]; retinoid metabolic process [GO:0001523]	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	intestinal cholesterol absorption [GO:0030299]; lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241]; lipid metabolic process [GO:0006629]; positive regulation of triglyceride lipase activity [GO:0061365]; retinoid metabolic process [GO:0001523]	hemolysis in other organism [GO:0044179]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1lpbb1_d1qmda2__1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; extracellular space [GO:0005615]; lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; intestinal cholesterol absorption [GO:0030299]; lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241]; lipid metabolic process [GO:0006629]; positive regulation of triglyceride lipase activity [GO:0061365]; retinoid metabolic process [GO:0001523]	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	intestinal cholesterol absorption [GO:0030299]; lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241]; lipid metabolic process [GO:0006629]; positive regulation of triglyceride lipase activity [GO:0061365]; retinoid metabolic process [GO:0001523]	hemolysis in other organism [GO:0044179]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1lpbb2_d1gz7c___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular region [GO:0005576]; extracellular space [GO:0005615]; lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; intestinal cholesterol absorption [GO:0030299]; lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241]; lipid metabolic process [GO:0006629]; positive regulation of triglyceride lipase activity [GO:0061365]; retinoid metabolic process [GO:0001523]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	intestinal cholesterol absorption [GO:0030299]; lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241]; lipid metabolic process [GO:0006629]; positive regulation of triglyceride lipase activity [GO:0061365]; retinoid metabolic process [GO:0001523]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; extracellular space [GO:0005615]		lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	triglyceride lipase activity [GO:0004806]
d1lpda__d3d7wa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1lpfb2_d4gr1a2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]; glycolytic process [GO:0006096]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cell redox homeostasis [GO:0045454]; glycolytic process [GO:0006096]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]
d1lpgb__d4wmed___1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]
d1lpja__d4ykob___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; retinal binding [GO:0016918]; retinol binding [GO:0019841]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	retinal binding [GO:0016918]; retinol binding [GO:0019841]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1lpma__d3fyta___1	Fungi		Ascomycota	Firmicutes	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	acetylesterase activity [GO:0008126]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	acetylesterase activity [GO:0008126]
d1lpna__d4k2ab___1	Fungi		Ascomycota	Proteobacteria	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	haloalkane dehalogenase activity [GO:0018786]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	haloalkane dehalogenase activity [GO:0018786]
d1lpoa__d3w9ba___1	Fungi	Fungi	Ascomycota	Basidiomycota	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]			triglyceride lipase activity [GO:0004806]	triglyceride lipase activity [GO:0004806]
d1lpoa__d4ehba___1	Fungi		Ascomycota	Proteobacteria	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	hydrolase activity [GO:0016787]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	hydrolase activity [GO:0016787]
d1lppa__d2nw6a___1	Fungi		Ascomycota	Proteobacteria	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d1lpsa__d3fyug___1	Fungi		Ascomycota	Firmicutes	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	acetylesterase activity [GO:0008126]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	acetylesterase activity [GO:0008126]
d1lq2a1_d1q6ca___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d1lqba__d2jf5b___1	Metazoa	Metazoa	Chordata	Chordata	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1lqfd1_d5bugb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; ubiquitin-specific protease binding [GO:1990381]; adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381]
d1lqga__d2oyta2__1		Metazoa	Proteobacteria	Chordata	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	uracil DNA N-glycosylase activity [GO:0004844]	damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]
d1lqja1_d2zhxe___1			Proteobacteria	Actinobacteria	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d1lqka__d2p7mc___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; metal ion binding [GO:0046872]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1lqli1_d1nyea___1			Tenericutes	Proteobacteria	cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]	cytosol [GO:0005829]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; hyperosmotic response [GO:0006972]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]		hyperosmotic response [GO:0006972]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	peroxidase activity [GO:0004601]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1lqma__d4wpka1__1			Proteobacteria	Actinobacteria	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d1lqob__d1jifa___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; metal ion binding [GO:0046872]; response to antibiotic [GO:0046677]	drug binding [GO:0008144]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]; metal ion binding [GO:0046872]	drug binding [GO:0008144]
d1lqsr1_d1ebpa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; interleukin-10 binding [GO:0019969]; interleukin-10 receptor activity [GO:0004920]; signaling receptor activity [GO:0038023]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of autophagy [GO:0010507]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of synapse organization [GO:0050807]; response to lipopolysaccharide [GO:0032496]; ubiquitin-dependent endocytosis [GO:0070086]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	cytokine-mediated signaling pathway [GO:0019221]; negative regulation of autophagy [GO:0010507]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of synapse organization [GO:0050807]; response to lipopolysaccharide [GO:0032496]; ubiquitin-dependent endocytosis [GO:0070086]	brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]	cytokine receptor activity [GO:0004896]; interleukin-10 binding [GO:0019969]; interleukin-10 receptor activity [GO:0004920]; signaling receptor activity [GO:0038023]	erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]
d1lqsr1_d3lpwa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; interleukin-10 binding [GO:0019969]; interleukin-10 receptor activity [GO:0004920]; signaling receptor activity [GO:0038023]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of autophagy [GO:0010507]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of synapse organization [GO:0050807]; response to lipopolysaccharide [GO:0032496]; ubiquitin-dependent endocytosis [GO:0070086]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cytokine-mediated signaling pathway [GO:0019221]; negative regulation of autophagy [GO:0010507]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of synapse organization [GO:0050807]; response to lipopolysaccharide [GO:0032496]; ubiquitin-dependent endocytosis [GO:0070086]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cytokine receptor activity [GO:0004896]; interleukin-10 binding [GO:0019969]; interleukin-10 receptor activity [GO:0004920]; signaling receptor activity [GO:0038023]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1lqwa__d3qu1b___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; translation [GO:0006412]	formylmethionine deformylase activity [GO:0008463]; metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; cellular protein modification process [GO:0006464]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	translation [GO:0006412]	cellular protein modification process [GO:0006464]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]			metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]	formylmethionine deformylase activity [GO:0008463]; metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d1lr5b__d4luka___1	Viridiplantae		Streptophyta	Euryarchaeota	endoplasmic reticulum lumen [GO:0005788]; auxin binding [GO:0010011]; zinc ion binding [GO:0008270]; auxin-activated signaling pathway [GO:0009734]; cytokinesis by cell plate formation [GO:0000911]; positive regulation of cell division [GO:0051781]; positive regulation of cell size [GO:0045793]; positive regulation of DNA endoreduplication [GO:0032877]; unidimensional cell growth [GO:0009826]	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	auxin-activated signaling pathway [GO:0009734]; cytokinesis by cell plate formation [GO:0000911]; positive regulation of cell division [GO:0051781]; positive regulation of cell size [GO:0045793]; positive regulation of DNA endoreduplication [GO:0032877]; unidimensional cell growth [GO:0009826]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	endoplasmic reticulum lumen [GO:0005788]	cytoplasm [GO:0005737]	auxin binding [GO:0010011]; zinc ion binding [GO:0008270]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]
d1lr6a__d3lf5a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; perinuclear region of cytoplasm [GO:0048471]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; bicarbonate transport [GO:0015701]; cell development [GO:0048468]; detection of oxygen [GO:0003032]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; insulin secretion [GO:0030073]; oxidation-reduction process [GO:0055114]; response to antibiotic [GO:0046677]; superoxide metabolic process [GO:0006801]	oxidation-reduction process [GO:0055114]	bicarbonate transport [GO:0015701]; cell development [GO:0048468]; detection of oxygen [GO:0003032]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; insulin secretion [GO:0030073]; oxidation-reduction process [GO:0055114]; response to antibiotic [GO:0046677]; superoxide metabolic process [GO:0006801]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; perinuclear region of cytoplasm [GO:0048471]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d1lrha__d1v70a___1	Viridiplantae		Streptophyta	Deinococcus-Thermus	endoplasmic reticulum lumen [GO:0005788]; auxin binding [GO:0010011]; zinc ion binding [GO:0008270]; auxin-activated signaling pathway [GO:0009734]; cytokinesis by cell plate formation [GO:0000911]; positive regulation of cell division [GO:0051781]; positive regulation of cell size [GO:0045793]; positive regulation of DNA endoreduplication [GO:0032877]; unidimensional cell growth [GO:0009826]		auxin-activated signaling pathway [GO:0009734]; cytokinesis by cell plate formation [GO:0000911]; positive regulation of cell division [GO:0051781]; positive regulation of cell size [GO:0045793]; positive regulation of DNA endoreduplication [GO:0032877]; unidimensional cell growth [GO:0009826]		endoplasmic reticulum lumen [GO:0005788]		auxin binding [GO:0010011]; zinc ion binding [GO:0008270]	
d1lrhc__d2ixka___1	Viridiplantae		Streptophyta	Proteobacteria	endoplasmic reticulum lumen [GO:0005788]; auxin binding [GO:0010011]; zinc ion binding [GO:0008270]; auxin-activated signaling pathway [GO:0009734]; cytokinesis by cell plate formation [GO:0000911]; positive regulation of cell division [GO:0051781]; positive regulation of cell size [GO:0045793]; positive regulation of DNA endoreduplication [GO:0032877]; unidimensional cell growth [GO:0009826]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	auxin-activated signaling pathway [GO:0009734]; cytokinesis by cell plate formation [GO:0000911]; positive regulation of cell division [GO:0051781]; positive regulation of cell size [GO:0045793]; positive regulation of DNA endoreduplication [GO:0032877]; unidimensional cell growth [GO:0009826]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	endoplasmic reticulum lumen [GO:0005788]		auxin binding [GO:0010011]; zinc ion binding [GO:0008270]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d1lrhd__d6bgma___1	Viridiplantae	Metazoa	Streptophyta	Chordata	endoplasmic reticulum lumen [GO:0005788]; auxin binding [GO:0010011]; zinc ion binding [GO:0008270]; auxin-activated signaling pathway [GO:0009734]; cytokinesis by cell plate formation [GO:0000911]; positive regulation of cell division [GO:0051781]; positive regulation of cell size [GO:0045793]; positive regulation of DNA endoreduplication [GO:0032877]; unidimensional cell growth [GO:0009826]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; inflammatory response [GO:0006954]; L-cysteine catabolic process [GO:0019448]; lactation [GO:0007595]; oxidation-reduction process [GO:0055114]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; sulfur amino acid biosynthetic process [GO:0000097]; taurine biosynthetic process [GO:0042412]	auxin-activated signaling pathway [GO:0009734]; cytokinesis by cell plate formation [GO:0000911]; positive regulation of cell division [GO:0051781]; positive regulation of cell size [GO:0045793]; positive regulation of DNA endoreduplication [GO:0032877]; unidimensional cell growth [GO:0009826]	cysteine metabolic process [GO:0006534]; inflammatory response [GO:0006954]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; oxidation-reduction process [GO:0055114]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; sulfur amino acid biosynthetic process [GO:0000097]; taurine biosynthetic process [GO:0042412]	endoplasmic reticulum lumen [GO:0005788]	cytosol [GO:0005829]	auxin binding [GO:0010011]; zinc ion binding [GO:0008270]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d1lrja__d1he4a___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]; carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; terminal bouton [GO:0043195]; biliverdin reductase activity [GO:0004074]; riboflavin reductase (NADPH) activity [GO:0042602]; heme catabolic process [GO:0042167]	carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	heme catabolic process [GO:0042167]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; terminal bouton [GO:0043195]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]	biliverdin reductase activity [GO:0004074]; riboflavin reductase (NADPH) activity [GO:0042602]
d1lrqa__d1w8se___1			Aquificae	Crenarchaeota	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	fructose-bisphosphate aldolase activity [GO:0004332]
d1lrub__d1lqya___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	translation [GO:0006412]	cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d1lrwa__d2d0vd___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol oxidation [GO:0015946]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; calcium ion binding [GO:0005509]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]	methanol oxidation [GO:0015946]		periplasmic space [GO:0042597]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]	calcium ion binding [GO:0005509]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]
d1ls0a5_d5fyjv___1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1ls0a6_d1igyb4__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ls0a6_d4yhnl2__1												
d1ls0b4_d3gsvb1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ls0b6_d1ovza1__1		Metazoa		Chordata		extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]
d1ls5a__d5t2za___1			Apicomplexa		food vacuole [GO:0020020]; aspartic-type endopeptidase activity [GO:0004190]; hemoglobin catabolic process [GO:0042540]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		hemoglobin catabolic process [GO:0042540]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		food vacuole [GO:0020020]		aspartic-type endopeptidase activity [GO:0004190]	
d1ls6a__d3tsoa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; aryl sulfotransferase activity [GO:0004062]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasmic vesicle membrane [GO:0030659]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; phagocytic cup [GO:0001891]; recycling endosome membrane [GO:0055038]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; establishment of cell polarity [GO:0030010]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; phagocytosis [GO:0006909]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulated exocytosis [GO:0045055]; renal water homeostasis [GO:0003091]; TRAM-dependent toll-like receptor 4 signaling pathway [GO:0035669]	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]	establishment of cell polarity [GO:0030010]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; phagocytosis [GO:0006909]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulated exocytosis [GO:0045055]; renal water homeostasis [GO:0003091]; TRAM-dependent toll-like receptor 4 signaling pathway [GO:0035669]	cytosol [GO:0005829]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasmic vesicle membrane [GO:0030659]; endosome [GO:0005768]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; phagocytic cup [GO:0001891]; recycling endosome membrane [GO:0055038]	aryl sulfotransferase activity [GO:0004062]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]
d1lsaa__d1p6ya___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lsda__d2o79a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lsea__d1cu2a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lsja2_d1wdlb3__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	fatty acid beta-oxidation [GO:0006635]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d1lsja2_d4z9yc___1	Metazoa		Chordata		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]		3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]	
d1lsma__d1c6ga___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lsna__d1gf3a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1lsna__d2nzka___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1lspa__d153la___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lssa__d5t5qd___1			Euryarchaeota	Proteobacteria	plasma membrane [GO:0005886]; potassium ion transmembrane transporter activity [GO:0015079]	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; nucleotide binding [GO:0000166]			plasma membrane [GO:0005886]		potassium ion transmembrane transporter activity [GO:0015079]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; nucleotide binding [GO:0000166]
d1lssc__d1hf3b2__1		Metazoa	Euryarchaeota	Chordata	plasma membrane [GO:0005886]; potassium ion transmembrane transporter activity [GO:0015079]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	plasma membrane [GO:0005886]	cytosol [GO:0005829]	potassium ion transmembrane transporter activity [GO:0015079]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1lssd__d4ei2i1__1			Euryarchaeota	Euryarchaeota	plasma membrane [GO:0005886]; potassium ion transmembrane transporter activity [GO:0015079]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]		potassium ion transport [GO:0006813]	plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	potassium ion transmembrane transporter activity [GO:0015079]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1lsua__d3aogj2__1			Firmicutes	Deinococcus-Thermus	plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; potassium ion transport [GO:0006813]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	potassium ion transport [GO:0006813]	cellular amino acid metabolic process [GO:0006520]	plasma membrane [GO:0005886]		cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1lsza__d1lz6a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1lsza__d5jwva___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lt5d__d1tiie___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1lt6m__d1b44d___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1lt9b1_d2j2pd___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1lt9c1_d4jzca___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]
d1ltad__d1bosk___1			Proteobacteria		extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	killing of cells of other organism [GO:0031640]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ltae__d1r4qc___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; negative regulation of translation [GO:0017148]	killing of cells of other organism [GO:0031640]	negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]		toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1ltaf__d1bcpf___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ltaf__d1i4ha1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]
d1ltag__d1qohg___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1ltah__d5elba___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1ltbg__d1fnwa1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ltda2_d1t0ga___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	cytosol [GO:0005829]; nucleus [GO:0005634]; vacuole [GO:0005773]; steroid binding [GO:0005496]	lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]	cytosol [GO:0005829]; nucleus [GO:0005634]; vacuole [GO:0005773]	heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]	steroid binding [GO:0005496]
d1ltda2_d2i89b___1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]	heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1ltgh__d4fo2t___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1lthr1_d4kugb1__1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	glycolytic process [GO:0006096]	fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]
d1lthr2_d2xxeb2__1			Actinobacteria		cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	
d1ltht2_d2fnza4__1			Actinobacteria		cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	
d1ltid__d1qilb1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ltjc1_d2j2pe___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1ltjf1_d2j0hf___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1ltoa__d5dkma___1	Metazoa		Chordata	Actinobacteria	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	serine-type endopeptidase activity [GO:0004252]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase activity [GO:0004252]
d1ltrg__d4rh6b1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1lts.1_d4hhya2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	killing of cells of other organism [GO:0031640]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	toxin activity [GO:0090729]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1ltsd__d4fp5d___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ltse__d1czwj___1			Proteobacteria		extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	killing of cells of other organism [GO:0031640]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ltsh__d4zysa1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1lttd__d1prti1__1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ltte__d1ltrf___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1lttg__d4fo2i___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ltth__d1s5bf___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]	toxin activity [GO:0090729]	galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]
d1lu2b__d1igob___1	Viridiplantae		Streptophyta	Firmicutes	mannose binding [GO:0005537]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			mannose binding [GO:0005537]	endo-1,4-beta-xylanase activity [GO:0031176]
d1lu9b2_d5ijzd1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; glutamate biosynthetic process [GO:0006537]	formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	glutamate biosynthetic process [GO:0006537]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	glutamate dehydrogenase (NADP+) activity [GO:0004354]
d1lu9c1_d1hwzd1__1			Proteobacteria		cytoplasm [GO:0005737]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]		formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]		cytoplasm [GO:0005737]		methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	
d1luab1_d4qo8d1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1luac1_d1c1da1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	cytoplasm [GO:0005737]		methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d1luac1_d1qsgb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]
d1lusa4_d1xrea2__1				Firmicutes		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]				metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1lusb4_d3js4a2__1				Proteobacteria		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]						metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1luvb2_d1wb7a2__1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1luvb2_d4guno2__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1luwa1_d3ak3b1__1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1luwb1_d2nybb1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]
d1lv1a2_d5p3la___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	aspartic-type endopeptidase activity [GO:0004190]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1lv5a1_d3rmba1__1			Firmicutes		3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1lvea__d4qhnb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]	
d1lvga__d4dlra___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; photoreceptor inner segment [GO:0001917]; ATP binding [GO:0005524]; guanylate kinase activity [GO:0004385]; ATP metabolic process [GO:0046034]; dATP metabolic process [GO:0046060]; dGDP biosynthetic process [GO:0006185]; dGMP metabolic process [GO:0046054]; GDP biosynthetic process [GO:0046711]; GDP-mannose metabolic process [GO:0019673]; glycoprotein transport [GO:0034436]; GMP metabolic process [GO:0046037]; nucleotide phosphorylation [GO:0046939]; purine nucleotide metabolic process [GO:0006163]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	ATP metabolic process [GO:0046034]; dATP metabolic process [GO:0046060]; dGDP biosynthetic process [GO:0006185]; dGMP metabolic process [GO:0046054]; GDP biosynthetic process [GO:0046711]; GDP-mannose metabolic process [GO:0019673]; glycoprotein transport [GO:0034436]; GMP metabolic process [GO:0046037]; nucleotide phosphorylation [GO:0046939]; purine nucleotide metabolic process [GO:0006163]; xenobiotic metabolic process [GO:0006805]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytosol [GO:0005829]; photoreceptor inner segment [GO:0001917]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; guanylate kinase activity [GO:0004385]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1lvla3_d1grta3__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]; glycolytic process [GO:0006096]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cell redox homeostasis [GO:0045454]; glycolytic process [GO:0006096]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]
d1lvmb__d3keeb___1					helical viral capsid [GO:0019029]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]; RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	helical viral capsid [GO:0019029]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1lvna2_d1avka2__1			Proteobacteria	Actinobacteria	periplasmic space [GO:0042597]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	amine metabolic process [GO:0009308]	periplasmic space [GO:0042597]		aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d1lvoc__d2gdda___1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	proteolysis [GO:0006508]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1lvoc__d4x2vc___1					host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]
d1lvod__d1cgje___1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1lvof__d1eaia___1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular space [GO:0005615]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1lw1a__d1p8cf___1			Actinobacteria	Thermotogae	cell [GO:0005623]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; alkyl hydroperoxide reductase activity [GO:0008785]; disulfide oxidoreductase activity [GO:0015036]; hydroperoxide reductase activity [GO:0032843]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		alkyl hydroperoxide reductase activity [GO:0008785]; disulfide oxidoreductase activity [GO:0015036]; hydroperoxide reductase activity [GO:0032843]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1lw1c__d2gmye___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; alkyl hydroperoxide reductase activity [GO:0008785]; disulfide oxidoreductase activity [GO:0015036]; hydroperoxide reductase activity [GO:0032843]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		alkyl hydroperoxide reductase activity [GO:0008785]; disulfide oxidoreductase activity [GO:0015036]; hydroperoxide reductase activity [GO:0032843]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1lw3a1_d2d10a2__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]; identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d1lw9a__d2huma___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lwdb__d1dpzb___1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrion [GO:0005739]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; 2-oxoglutarate metabolic process [GO:0006103]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	2-oxoglutarate metabolic process [GO:0006103]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1lwga__d4wm6d___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1lwha2_d1j0ia3__1			Thermotogae	Firmicutes	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]; oligosaccharide catabolic process [GO:0009313]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	oligosaccharide catabolic process [GO:0009313]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1lwha2_d1v6wa2__1			Thermotogae	Actinobacteria	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]; oligosaccharide catabolic process [GO:0009313]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	oligosaccharide catabolic process [GO:0009313]	polysaccharide catabolic process [GO:0000272]	cytoplasm [GO:0005737]		4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d1lwhb2_d1kxtc2__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]; oligosaccharide catabolic process [GO:0009313]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	oligosaccharide catabolic process [GO:0009313]	carbohydrate catabolic process [GO:0016052]	cytoplasm [GO:0005737]	extracellular space [GO:0005615]	4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1lwja2_d3bsga2__1		Viridiplantae	Thermotogae	Streptophyta	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]; oligosaccharide catabolic process [GO:0009313]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	oligosaccharide catabolic process [GO:0009313]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]	extracellular space [GO:0005615]	4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1lwjb2_d3o6aa___1		Fungi	Thermotogae	Ascomycota	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]; oligosaccharide catabolic process [GO:0009313]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]; cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	oligosaccharide catabolic process [GO:0009313]	cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	cytoplasm [GO:0005737]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]	4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]	cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]
d1lwma__d1j47a1__1	Fungi	Metazoa	Ascomycota	Chordata	nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; DNA binding, bending [GO:0008301]; MutSalpha complex binding [GO:0032407]; nucleosome binding [GO:0031491]; chromatin remodeling [GO:0006338]; DNA replication-independent nucleosome organization [GO:0034724]; maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter [GO:0001195]; mismatch repair [GO:0006298]; negative regulation of DNA binding [GO:0043392]; protein-DNA complex assembly [GO:0065004]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; calmodulin binding [GO:0005516]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; transcription factor binding [GO:0008134]; cell differentiation [GO:0030154]; male sex determination [GO:0030238]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of male gonad development [GO:2000020]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; sex differentiation [GO:0007548]	chromatin remodeling [GO:0006338]; DNA replication-independent nucleosome organization [GO:0034724]; maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter [GO:0001195]; mismatch repair [GO:0006298]; negative regulation of DNA binding [GO:0043392]; protein-DNA complex assembly [GO:0065004]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]	cell differentiation [GO:0030154]; male sex determination [GO:0030238]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of male gonad development [GO:2000020]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; sex differentiation [GO:0007548]	nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding, bending [GO:0008301]; MutSalpha complex binding [GO:0032407]; nucleosome binding [GO:0031491]	calmodulin binding [GO:0005516]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; transcription factor binding [GO:0008134]
d1lwuc1_d2d39c___1	Metazoa	Metazoa	Chordata	Chordata	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]; cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	fibrinogen complex [GO:0005577]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]	carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]
d1lwui1_d2j61a___1	Metazoa	Metazoa	Chordata	Chordata	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	fibrinogen complex [GO:0005577]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1lwuk1_d2j3ud___1	Metazoa	Metazoa	Chordata	Chordata	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	fibrinogen complex [GO:0005577]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1lwxa__d3ztsk___1				Aquificae	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1lwxb__d5v6dl___1				Proteobacteria	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1lxka1_d1c82a1__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d1lxka3_d3d4za2__1		Metazoa	Firmicutes	Arthropoda	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	cell wall [GO:0005618]; extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1lxma1_d1hm2a1__1			Firmicutes	Bacteroidetes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]
d1lxma2_d2p5pb___1			Firmicutes		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; peptidase activity [GO:0008233]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive regulation of viral genome replication [GO:0045070]; RNA 5'-cap (guanine-N7)-methylation [GO:0106005]; RNA stabilization [GO:0043489]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive regulation of viral genome replication [GO:0045070]; RNA 5'-cap (guanine-N7)-methylation [GO:0106005]; RNA stabilization [GO:0043489]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	ATP binding [GO:0005524]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; peptidase activity [GO:0008233]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1lxta1_d3pmgb2__1	Metazoa	Metazoa	Chordata	Chordata	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	glucose metabolic process [GO:0006006]	glucose metabolic process [GO:0006006]	sarcoplasmic reticulum [GO:0016529]	sarcoplasmic reticulum [GO:0016529]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1lxta4_d1wjwa1__1	Metazoa	Metazoa	Chordata	Chordata	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	magnesium ion binding [GO:0000287]; phosphoacetylglucosamine mutase activity [GO:0004610]; phosphoglucomutase activity [GO:0004614]; carbohydrate metabolic process [GO:0005975]; glucose 1-phosphate metabolic process [GO:0019255]; hemopoiesis [GO:0030097]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; spermatogenesis [GO:0007283]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	glucose metabolic process [GO:0006006]	carbohydrate metabolic process [GO:0005975]; glucose 1-phosphate metabolic process [GO:0019255]; hemopoiesis [GO:0030097]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; spermatogenesis [GO:0007283]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	sarcoplasmic reticulum [GO:0016529]		magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoacetylglucosamine mutase activity [GO:0004610]; phosphoglucomutase activity [GO:0004614]
d1ly7a__d3ias7___1	Metazoa		Chordata	Deinococcus-Thermus	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]		cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]	quinone binding [GO:0048038]
d1ly8a__d5jhya1__1	Fungi	Fungi	Basidiomycota	Ascomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1ly9a__d5jhza1__1	Fungi	Fungi	Basidiomycota	Ascomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1ly9b__d1besa___1	Fungi	Fungi	Basidiomycota	Ascomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1lya.1_d1sdta___1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane raft [GO:0045121]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; aspartic-type endopeptidase activity [GO:0004190]; aspartic-type peptidase activity [GO:0070001]; peptidase activity [GO:0008233]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; collagen catabolic process [GO:0030574]; lipoprotein catabolic process [GO:0042159]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of establishment of protein localization [GO:0070201]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; collagen catabolic process [GO:0030574]; lipoprotein catabolic process [GO:0042159]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of establishment of protein localization [GO:0070201]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	collagen-containing extracellular matrix [GO:0062023]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane raft [GO:0045121]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; aspartic-type peptidase activity [GO:0070001]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1lya.2_d4rldd1__1	Metazoa	Metazoa	Chordata	Arthropoda	collagen-containing extracellular matrix [GO:0062023]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane raft [GO:0045121]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; aspartic-type endopeptidase activity [GO:0004190]; aspartic-type peptidase activity [GO:0070001]; peptidase activity [GO:0008233]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; collagen catabolic process [GO:0030574]; lipoprotein catabolic process [GO:0042159]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of establishment of protein localization [GO:0070201]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; collagen catabolic process [GO:0030574]; lipoprotein catabolic process [GO:0042159]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of establishment of protein localization [GO:0070201]		collagen-containing extracellular matrix [GO:0062023]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane raft [GO:0045121]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		aspartic-type endopeptidase activity [GO:0004190]; aspartic-type peptidase activity [GO:0070001]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]
d1lyca__d3m2ba___1	Fungi	Fungi	Basidiomycota	Ascomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1lyda__d1cj7a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1lyga__d3hh4a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lyia__d5kxsa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1lyja__d4ppoa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1lyka__d5sywb2__1	Fungi		Basidiomycota	Proteobacteria	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1lyla1_d1eqrb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]
d1lyla2_d1eiya2__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	phenylalanyl-tRNA aminoacylation [GO:0006432]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]
d1lylb1_d1g51a1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]
d1lyw.2_d1ythb___1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane raft [GO:0045121]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; aspartic-type endopeptidase activity [GO:0004190]; aspartic-type peptidase activity [GO:0070001]; peptidase activity [GO:0008233]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; collagen catabolic process [GO:0030574]; lipoprotein catabolic process [GO:0042159]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of establishment of protein localization [GO:0070201]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; collagen catabolic process [GO:0030574]; lipoprotein catabolic process [GO:0042159]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of establishment of protein localization [GO:0070201]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	collagen-containing extracellular matrix [GO:0062023]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane raft [GO:0045121]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; aspartic-type peptidase activity [GO:0070001]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1lyya__d1ioca1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1lz1a__d5jgva___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lz5a__d4eksb1__1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lz8a__d109la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lzca__d3hbda___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d1lzda__d1zyta___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lzda__d2bqba___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1lzoa__d1suxb___1			Apicomplexa		identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		glycosome [GO:0020015]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1lzoa__d4y90a___1			Apicomplexa	Deinococcus-Thermus	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]		cytosol [GO:0005829]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1lzoc__d1kv5a___1			Apicomplexa		identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]; glycosome [GO:0020015]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1lzsb__d2rbqa___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1lzva__d1heda___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1lzwa__d4yjxc___1			Proteobacteria	Proteobacteria	chaperone binding [GO:0051087]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]			chaperone binding [GO:0051087]	
d1lzya__d5m1yb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1m03a1_d3w24a___1			Actinobacteria	Firmicutes	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]			beta-N-acetylhexosaminidase activity [GO:0004563]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d1m05c1_d4lvhc1__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]
d1m05d__d5m2mj1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d1m0ba__d4gidd___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d1m0da__d1cfra___1				Proteobacteria	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	DNA restriction-modification system [GO:0009307]			deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]	metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]
d1m0dc__d3caed___1					deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]			deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]
d1m0ea__d3ubtb___1			Proteobacteria	Proteobacteria	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d1m0ea__d4oa5c___1			Proteobacteria	Proteobacteria	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	O-methyltransferase activity [GO:0008171]	DNA restriction-modification system [GO:0009307]				DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	O-methyltransferase activity [GO:0008171]
d1m0ia__d3caea___1					deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]			deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]
d1m0tb1_d1a9xg4__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; glutathione binding [GO:0043295]; glutathione synthase activity [GO:0004363]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; glutathione biosynthetic process [GO:0006750]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	glutathione biosynthetic process [GO:0006750]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; glutathione binding [GO:0043295]; glutathione synthase activity [GO:0004363]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1m0ub1_d2hqtt___1	Metazoa	Fungi	Arthropoda	Ascomycota	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; prostaglandin-D synthase activity [GO:0004667]; glutathione metabolic process [GO:0006749]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]; enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]; positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	glutathione metabolic process [GO:0006749]; response to oxidative stress [GO:0006979]	positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; prostaglandin-D synthase activity [GO:0004667]	enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]
d1m0wa1_d1dv1b2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; glutathione binding [GO:0043295]; glutathione synthase activity [GO:0004363]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; glutathione biosynthetic process [GO:0006750]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	glutathione biosynthetic process [GO:0006750]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; glutathione binding [GO:0043295]; glutathione synthase activity [GO:0004363]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1m0zb__d1xcda___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; thrombin-activated receptor activity [GO:0015057]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	collagen-containing extracellular matrix [GO:0062023]; collagen binding [GO:0005518]; collagen fibril binding [GO:0098633]; extracellular matrix binding [GO:0050840]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; glycosaminoglycan binding [GO:0005539]; protein homodimerization activity [GO:0042803]; negative regulation of angiogenesis [GO:0016525]; negative regulation of collagen fibril organization [GO:1904027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800]; positive regulation of macroautophagy [GO:0016239]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of transcription by RNA polymerase II [GO:0045944]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	negative regulation of angiogenesis [GO:0016525]; negative regulation of collagen fibril organization [GO:1904027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800]; positive regulation of macroautophagy [GO:0016239]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of transcription by RNA polymerase II [GO:0045944]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]	thrombin-activated receptor activity [GO:0015057]	collagen binding [GO:0005518]; collagen fibril binding [GO:0098633]; extracellular matrix binding [GO:0050840]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; glycosaminoglycan binding [GO:0005539]; protein homodimerization activity [GO:0042803]
d1m10b__d2omta3__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1m15a1_d3l2gg1__1	Metazoa		Arthropoda		cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]		arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	
d1m18g__d5b33c___1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; DNA-templated transcription, initiation [GO:0006352]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	DNA-templated transcription, initiation [GO:0006352]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleosome [GO:0000786]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1m19c__d5f99h___1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; DNA-templated transcription, initiation [GO:0006352]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA-templated transcription, initiation [GO:0006352]		nucleosome [GO:0000786]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1m19g__d3mgqa___1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; DNA-templated transcription, initiation [GO:0006352]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA-templated transcription, initiation [GO:0006352]		nucleosome [GO:0000786]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1m1ab__d4m6ba1__1	Metazoa	Fungi	Chordata	Ascomycota	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; DNA-templated transcription, initiation [GO:0006352]	nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleosome [GO:0000786]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromatin silencing at silent mating-type cassette [GO:0030466]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; regulation of transcription by RNA polymerase II [GO:0006357]	DNA-templated transcription, initiation [GO:0006352]	chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromatin silencing at silent mating-type cassette [GO:0030466]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleosome [GO:0000786]; nucleus [GO:0005634]	nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d1m1ad__d4wnng___1	Metazoa	Fungi	Chordata	Ascomycota	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; DNA-templated transcription, initiation [GO:0006352]	nuclear nucleosome [GO:0000788]; replication fork protection complex [GO:0031298]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin assembly or disassembly [GO:0006333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334]; postreplication repair [GO:0006301]	DNA-templated transcription, initiation [GO:0006352]	chromatin assembly or disassembly [GO:0006333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334]; postreplication repair [GO:0006301]	nucleosome [GO:0000786]; nucleus [GO:0005634]	nuclear nucleosome [GO:0000788]; replication fork protection complex [GO:0031298]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1m1af__d1p3lc___1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; DNA-templated transcription, initiation [GO:0006352]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA-templated transcription, initiation [GO:0006352]		nucleosome [GO:0000786]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1m1je1_d2j0hc___1	Metazoa	Metazoa	Chordata	Chordata	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	fibrinogen complex [GO:0005577]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor binding [GO:0005102]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1m1jf1_d2j3ob1__1	Metazoa	Metazoa	Chordata	Chordata	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	fibrinogen complex [GO:0005577]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor binding [GO:0005102]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1m1kc1_d1yjwa1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1m1kd__d1zm2e1__1			Euryarchaeota	Proteobacteria	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d1m1ky__d1ffku___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1m1ma2_d1hn9b1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1m1ma2_d2byxc2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1m1mb1_d4jaqa2__1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	polyketide synthase complex [GO:0034081]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	polyketide synthase complex [GO:0034081]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1m1na__d3mfqa___1			Proteobacteria	Firmicutes	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	nitrogen fixation [GO:0009399]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	metal ion binding [GO:0046872]
d1m1nc__d5ovwf___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; cobalamin binding [GO:0031419]; cobalamin transport [GO:0015889]	nitrogen fixation [GO:0009399]	cobalamin transport [GO:0015889]	molybdenum-iron nitrogenase complex [GO:0016612]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	cobalamin binding [GO:0031419]
d1m1ne__d5giza1__1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	
d1m1nf__d3tnya___1			Proteobacteria		molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	
d1m1oa1_d4e1lb2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1m1ob1_d5f0vb2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; acetoacetic acid catabolic process [GO:0043442]; fatty acid beta-oxidation [GO:0006635]; protein homotetramerization [GO:0051289]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	acetoacetic acid catabolic process [GO:0043442]; fatty acid beta-oxidation [GO:0006635]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]; acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d1m1oc2_d2byyc2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1m1od1_d1yslb2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d1m1ta1_d4o9ad2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1m1tc1_d4ylta1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1m1td1_d1xesd2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	pinosylvin synthase activity [GO:0050198]
d1m1td2_d4jgab2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1m1ya__d1qh1b___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1m1ye__d1mf1a___1		Metazoa	Proteobacteria	Chordata	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; membrane [GO:0016020]; actin filament binding [GO:0051015]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; 'de novo' AMP biosynthetic process [GO:0044208]; AMP biosynthetic process [GO:0006167]; aspartate metabolic process [GO:0006531]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; glutamine metabolic process [GO:0006541]; IMP metabolic process [GO:0046040]; purine nucleotide metabolic process [GO:0006163]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to muscle activity [GO:0014850]; response to starvation [GO:0042594]	nitrogen fixation [GO:0009399]	'de novo' AMP biosynthetic process [GO:0044208]; AMP biosynthetic process [GO:0006167]; aspartate metabolic process [GO:0006531]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; glutamine metabolic process [GO:0006541]; IMP metabolic process [GO:0046040]; purine nucleotide metabolic process [GO:0006163]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to muscle activity [GO:0014850]; response to starvation [GO:0042594]	molybdenum-iron nitrogenase complex [GO:0016612]	cytoplasm [GO:0005737]; membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	actin filament binding [GO:0051015]; adenylosuccinate synthase activity [GO:0004019]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]
d1m1yg__d3qusa___1			Proteobacteria	Firmicutes	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; tetrahydrofolate interconversion [GO:0035999]	nitrogen fixation [GO:0009399]	tetrahydrofolate interconversion [GO:0035999]	molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]
d1m1yi__d3mwfa___1			Proteobacteria	Firmicutes	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	
d1m1yk__d5bvgc___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1m1yl__d4filc___1			Proteobacteria	Firmicutes	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	metal ion binding [GO:0046872]	nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	metal ion binding [GO:0046872]
d1m1yo__d4lhwa___1		Metazoa	Proteobacteria	Chordata	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; cilium [GO:0005929]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; midbody [GO:0030496]; neuronal cell body [GO:0043025]; non-motile cilium [GO:0097730]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; recycling endosome membrane [GO:0055038]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; trans-Golgi network transport vesicle [GO:0030140]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin V binding [GO:0031489]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; autophagy [GO:0006914]; axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; cilium assembly [GO:0060271]; Golgi vesicle fusion to target membrane [GO:0048210]; intracellular protein transport [GO:0006886]; neurotransmitter receptor transport to postsynaptic membrane [GO:0098969]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; post-translational protein modification [GO:0043687]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; Rab protein signal transduction [GO:0032482]; regulation of autophagy [GO:0010506]; regulation of exocytosis [GO:0017157]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein transport [GO:0051223]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport in synapse [GO:0099003]	nitrogen fixation [GO:0009399]	autophagy [GO:0006914]; axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; cilium assembly [GO:0060271]; Golgi vesicle fusion to target membrane [GO:0048210]; intracellular protein transport [GO:0006886]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; neurotransmitter receptor transport to postsynaptic membrane [GO:0098969]; post-translational protein modification [GO:0043687]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; Rab protein signal transduction [GO:0032482]; regulation of autophagy [GO:0010506]; regulation of exocytosis [GO:0017157]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein transport [GO:0051223]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport in synapse [GO:0099003]	molybdenum-iron nitrogenase complex [GO:0016612]	centriole [GO:0005814]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; cilium [GO:0005929]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; midbody [GO:0030496]; neuronal cell body [GO:0043025]; non-motile cilium [GO:0097730]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; recycling endosome membrane [GO:0055038]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; trans-Golgi network transport vesicle [GO:0030140]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin V binding [GO:0031489]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]
d1m1yp__d3wyga___1		Fungi	Proteobacteria	Ascomycota	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; kinetochore [GO:0000776]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; spindle pole body [GO:0005816]; nuclear export signal receptor activity [GO:0005049]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; mRNA export from nucleus [GO:0006406]; protein export from nucleus [GO:0006611]; protein localization to kinetochore [GO:0034501]; regulation of protein export from nucleus [GO:0046825]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]	nitrogen fixation [GO:0009399]	mRNA export from nucleus [GO:0006406]; protein export from nucleus [GO:0006611]; protein localization to kinetochore [GO:0034501]; regulation of protein export from nucleus [GO:0046825]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]	molybdenum-iron nitrogenase complex [GO:0016612]	cytoplasm [GO:0005737]; kinetochore [GO:0000776]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; spindle pole body [GO:0005816]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	nuclear export signal receptor activity [GO:0005049]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]
d1m21a__d1obib___1			Proteobacteria	Proteobacteria		amidase activity [GO:0004040]						amidase activity [GO:0004040]
d1m26.3_d3r50e___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1m2aa__d4mcuc___1			Aquificae	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]; periplasmic space [GO:0042597]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]	protein disulfide oxidoreductase activity [GO:0015035]
d1m2ab__d1bq7f___1			Aquificae	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]		cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d1m2bb__d5b8ag___1		Metazoa	Aquificae	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]; activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	oxidation-reduction process [GO:0055114]	activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]	antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]
d1m2fa__d1b00a___1			Cyanobacteria	Proteobacteria	identical protein binding [GO:0042802]; circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of circadian rhythm [GO:0042753]; protein phosphorylation [GO:0006468]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of circadian rhythm [GO:0042753]; protein phosphorylation [GO:0006468]	phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	identical protein binding [GO:0042802]	bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1m2ka1_d1m2ha1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d1m2ma__d3x35a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1m2na1_d2fr8c___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	NAD binding [GO:0051287]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]; NADPH regeneration [GO:0006740]		NADPH regeneration [GO:0006740]	cytoplasm [GO:0005737]		NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]
d1m2tb1_d2d22b2__1	Viridiplantae		Streptophyta	Actinobacteria	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	endo-1,4-beta-xylanase activity [GO:0031176]
d1m2tb2_d4lo3a2__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]				carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	
d1m31a__d1m63b___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1m34a__d4k3vb___1			Proteobacteria		molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	
d1m34b__d4wzba___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1m34i__d1k7sn1__1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	outer membrane-bounded periplasmic space [GO:0030288]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	nitrogen fixation [GO:0009399]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	molybdenum-iron nitrogenase complex [GO:0016612]	outer membrane-bounded periplasmic space [GO:0030288]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	
d1m34j__d2r7ab___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	
d1m34k__d2m6ka___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; cellular response to DNA damage stimulus [GO:0006974]; ferric-enterobactin import into cell [GO:0015685]	nitrogen fixation [GO:0009399]	cellular response to DNA damage stimulus [GO:0006974]; ferric-enterobactin import into cell [GO:0015685]	molybdenum-iron nitrogenase complex [GO:0016612]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	
d1m34l__d2afhc___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1m35b2_d2gtxa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]		protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]	cytosol [GO:0005829]	aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]
d1m35b2_d3mr1c1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]		protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]		aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]
d1m35c1_d4pv4b1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	aminopeptidase activity [GO:0004177]; manganese ion binding [GO:0030145]			cytosol [GO:0005829]		aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	aminopeptidase activity [GO:0004177]; manganese ion binding [GO:0030145]
d1m35e1_d4pv4a1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	aminopeptidase activity [GO:0004177]; manganese ion binding [GO:0030145]			cytosol [GO:0005829]		aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	aminopeptidase activity [GO:0004177]; manganese ion binding [GO:0030145]
d1m38a__d4z71b1__1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1m3da1_d1m3df2__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]			basement membrane [GO:0005604]; collagen trimer [GO:0005581]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]
d1m3db1_d1t61d2__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]			basement membrane [GO:0005604]; collagen trimer [GO:0005581]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]
d1m3dc2_d1li1d1__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	collagen type IV trimer [GO:0005587]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; aging [GO:0007568]; angiogenesis [GO:0001525]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; negative regulation of angiogenesis [GO:0016525]; response to activity [GO:0014823]; transcription, DNA-templated [GO:0006351]		aging [GO:0007568]; angiogenesis [GO:0001525]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; negative regulation of angiogenesis [GO:0016525]; response to activity [GO:0014823]; transcription, DNA-templated [GO:0006351]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	collagen-containing extracellular matrix [GO:0062023]; collagen type IV trimer [GO:0005587]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]
d1m3dd2_d1t60x1__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]			basement membrane [GO:0005604]; collagen trimer [GO:0005581]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]
d1m3de1_d1t60r2__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]			basement membrane [GO:0005604]; collagen trimer [GO:0005581]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]
d1m3di2_d1m3dg1__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]			basement membrane [GO:0005604]; collagen trimer [GO:0005581]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]
d1m3ga__d5bugd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; mitogen-activated protein kinase binding [GO:0051019]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; inactivation of MAPK activity [GO:0000188]; protein dephosphorylation [GO:0006470]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; ubiquitin-specific protease binding [GO:1990381]; adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	inactivation of MAPK activity [GO:0000188]; protein dephosphorylation [GO:0006470]	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytoplasm [GO:0005737]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; mitogen-activated protein kinase binding [GO:0051019]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; protein tyrosine phosphatase activity [GO:0004725]	anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381]
d1m3ka1_d2qx1a2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d1m3kb1_d2bywd1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1m3kb2_d2buib1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1m3kd2_d2iwza1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1m3qa1_d1dizb1__1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1m3ya2_d1p30a2__1						host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]; viral capsid [GO:0019028]; structural molecule activity [GO:0005198]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]		microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]		host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]; viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d1m3yd2_d1hx6c1__1						viral capsid [GO:0019028]; virion [GO:0019012]				viral capsid [GO:0019028]; virion [GO:0019012]		
d1m3za2_d2vu2d1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1m3zb1_d1f91b2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1m3zb2_d1cmla1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	naringenin-chalcone synthase activity [GO:0016210]
d1m3zc2_d2aq7c2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1m43a__d5hvpa___1			Apicomplexa		vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1m46a__d4pe4x___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; MIH complex [GO:0120155]; myosin II complex [GO:0016460]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; myosin II heavy chain binding [GO:0032038]; myosin V binding [GO:0031489]; actomyosin contractile ring assembly [GO:0000915]; protein localization [GO:0008104]; vesicle targeting [GO:0006903]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	actomyosin contractile ring assembly [GO:0000915]; protein localization [GO:0008104]; vesicle targeting [GO:0006903]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; MIH complex [GO:0120155]; myosin II complex [GO:0016460]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; myosin II heavy chain binding [GO:0032038]; myosin V binding [GO:0031489]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1m4ga__d1s5ka1__1			Actinobacteria	Proteobacteria	plasma membrane [GO:0005886]; aminoglycoside 2'-N-acetyltransferase activity [GO:0047921]; aminoglycoside N-acetyltransferase activity [GO:0034069]; aminoglycoside antibiotic catabolic process [GO:0030649]; response to antibiotic [GO:0046677]	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]; protein homodimerization activity [GO:0042803]; acetyl-CoA metabolic process [GO:0006084]; histone acetylation [GO:0016573]; response to antibiotic [GO:0046677]	aminoglycoside antibiotic catabolic process [GO:0030649]; response to antibiotic [GO:0046677]	acetyl-CoA metabolic process [GO:0006084]; histone acetylation [GO:0016573]; response to antibiotic [GO:0046677]	plasma membrane [GO:0005886]		aminoglycoside 2'-N-acetyltransferase activity [GO:0047921]; aminoglycoside N-acetyltransferase activity [GO:0034069]	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]; protein homodimerization activity [GO:0042803]
d1m4gb__d5g1za1__1			Actinobacteria	Apicomplexa	plasma membrane [GO:0005886]; aminoglycoside 2'-N-acetyltransferase activity [GO:0047921]; aminoglycoside N-acetyltransferase activity [GO:0034069]; aminoglycoside antibiotic catabolic process [GO:0030649]; response to antibiotic [GO:0046677]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]	aminoglycoside antibiotic catabolic process [GO:0030649]; response to antibiotic [GO:0046677]	N-terminal protein myristoylation [GO:0006499]	plasma membrane [GO:0005886]		aminoglycoside 2'-N-acetyltransferase activity [GO:0047921]; aminoglycoside N-acetyltransferase activity [GO:0034069]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d1m4hb__d1vijb___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1m4ka1_d1e4kc1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; transmembrane signaling receptor activity [GO:0004888]; immune response [GO:0006955]; innate immune response [GO:0045087]; regulation of immune response [GO:0050776]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	immune response [GO:0006955]; innate immune response [GO:0045087]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	transmembrane signaling receptor activity [GO:0004888]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1m4rb__d3dgcl___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]; acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]; acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]	cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]
d1m4tb2_d4jb6b2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1m4tc2_d2wgfb2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]
d1m4va2_d3r8bg2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1m4yb__d2j6ha2__1			Thermotogae	Proteobacteria	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	proteolysis involved in cellular protein catabolic process [GO:0051603]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytosol [GO:0005829]	metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]
d1m56b1_d3qjtb2__1			Proteobacteria	Deinococcus-Thermus	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1m5ba__d3ttla___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	extracellular space [GO:0005615]; periplasmic space [GO:0042597]; spermidine binding [GO:0019809]; pathogenesis [GO:0009405]; polyamine transport [GO:0015846]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	pathogenesis [GO:0009405]; polyamine transport [GO:0015846]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	extracellular space [GO:0005615]; periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	spermidine binding [GO:0019809]
d1m5bb__d3qaxa1__1	Metazoa		Chordata	Chlamydiae	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell surface [GO:0009986]; extracellular region [GO:0005576]; amino acid transport [GO:0006865]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	amino acid transport [GO:0006865]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell surface [GO:0009986]; extracellular region [GO:0005576]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d1m5ec__d2zyna___1	Metazoa		Chordata	Firmicutes	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	plasma membrane [GO:0005886]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbohydrate transmembrane transporter activity [GO:0015144]
d1m5fa__d6bqea___1	Metazoa		Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d1m5fb__d4f29a___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1m5hd2_d2fhka2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]
d1m5hf2_d1m5ha1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]
d1m5hg2_d2fhjb1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]
d1m5kc__d2la6a1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	dendritic spine head [GO:0044327]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; estrogen receptor binding [GO:0030331]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; myosin V binding [GO:0031489]; retinoid X receptor binding [GO:0046965]; RNA binding [GO:0003723]; thyroid hormone receptor binding [GO:0046966]; transcription coactivator activity [GO:0003713]; cellular response to calcium ion [GO:0071277]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein homooligomerization [GO:0051260]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cellular response to calcium ion [GO:0071277]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein homooligomerization [GO:0051260]; regulation of RNA splicing [GO:0043484]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA splicing [GO:0008380]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	dendritic spine head [GO:0044327]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; estrogen receptor binding [GO:0030331]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; myosin V binding [GO:0031489]; retinoid X receptor binding [GO:0046965]; RNA binding [GO:0003723]; thyroid hormone receptor binding [GO:0046966]; transcription coactivator activity [GO:0003713]
d1m5oc__d2l08a1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exon-exon junction complex [GO:0035145]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA binding [GO:0003723]; structural constituent of nuclear pore [GO:0017056]; telomeric DNA binding [GO:0042162]; mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exon-exon junction complex [GO:0035145]; intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	RNA binding [GO:0003723]; structural constituent of nuclear pore [GO:0017056]; telomeric DNA binding [GO:0042162]
d1m5of__d1a9nb___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	catalytic step 2 spliceosome [GO:0071013]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small nuclear ribonucleoprotein complex [GO:0030532]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; RNA binding [GO:0003723]; U2 snRNA binding [GO:0030620]; interleukin-12-mediated signaling pathway [GO:0035722]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	interleukin-12-mediated signaling pathway [GO:0035722]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	catalytic step 2 spliceosome [GO:0071013]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small nuclear ribonucleoprotein complex [GO:0030532]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	RNA binding [GO:0003723]; U2 snRNA binding [GO:0030620]
d1m5sa1_d2fhkb2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]
d1m5sb1_d1m5ha2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]
d1m5sc1_d1m5hd1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]
d1m5sc2_d1m5hb1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]; lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	lactate oxidation [GO:0019516]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity [GO:0030270]
d1m5ta__d3ltev___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]			metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d1m5we__d3gk0e___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	cytoplasm [GO:0005737]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]	pyridoxine 5'-phosphate synthase activity [GO:0033856]
d1m5wf__d3gk0a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	cytoplasm [GO:0005737]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; pyridoxine 5'-phosphate synthase activity [GO:0033856]	pyridoxine 5'-phosphate synthase activity [GO:0033856]
d1m5xa__d1n3eg___1	Viridiplantae	Viridiplantae	Chlorophyta	Chlorophyta	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]		intron homing [GO:0006314]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1m5yc2_d2m1ia1__1			Proteobacteria	Thaumarchaeota	outer membrane-bounded periplasmic space [GO:0030288]; peptide binding [GO:0042277]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; chaperone cofactor-dependent protein refolding [GO:0051085]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; maintenance of stationary phase [GO:0060274]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	chaperone cofactor-dependent protein refolding [GO:0051085]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; maintenance of stationary phase [GO:0060274]; protein folding [GO:0006457]; protein stabilization [GO:0050821]		outer membrane-bounded periplasmic space [GO:0030288]		peptide binding [GO:0042277]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1m5za__d1whda1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; glucocorticoid receptor binding [GO:0035259]; receptor signaling complex adaptor activity [GO:0030159]; signaling receptor binding [GO:0005102]; dendrite development [GO:0016358]; nervous system development [GO:0007399]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection arborization [GO:0150012]; protein transport [GO:0015031]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; GTPase activator activity [GO:0005096]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; signal transduction [GO:0007165]	dendrite development [GO:0016358]; nervous system development [GO:0007399]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection arborization [GO:0150012]; protein transport [GO:0015031]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; signal transduction [GO:0007165]	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	glucocorticoid receptor binding [GO:0035259]; receptor signaling complex adaptor activity [GO:0030159]; signaling receptor binding [GO:0005102]	GTPase activator activity [GO:0005096]
d1m60a__d5b66v___1	Metazoa		Chordata	Cyanobacteria	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	integral component of membrane [GO:0016021]; photosystem II reaction center [GO:0009539]; thylakoid membrane [GO:0042651]; photosynthesis [GO:0015979]	apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	photosynthesis [GO:0015979]	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; photosystem II reaction center [GO:0009539]; thylakoid membrane [GO:0042651]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	
d1m61a2_d1o44a___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; adaptive immune response [GO:0002250]; B cell activation [GO:0042113]; beta selection [GO:0043366]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of T cell differentiation [GO:0045582]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; T cell activation [GO:0042110]; T cell aggregation [GO:0070489]; T cell differentiation [GO:0030217]; T cell migration [GO:0072678]; T cell receptor signaling pathway [GO:0050852]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	adaptive immune response [GO:0002250]; B cell activation [GO:0042113]; beta selection [GO:0043366]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of T cell differentiation [GO:0045582]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; T cell activation [GO:0042110]; T cell aggregation [GO:0070489]; T cell differentiation [GO:0030217]; T cell migration [GO:0072678]; T cell receptor signaling pathway [GO:0050852]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]
d1m61a2_d4dgxa2__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; adaptive immune response [GO:0002250]; B cell activation [GO:0042113]; beta selection [GO:0043366]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of T cell differentiation [GO:0045582]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; T cell activation [GO:0042110]; T cell aggregation [GO:0070489]; T cell differentiation [GO:0030217]; T cell migration [GO:0072678]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]; abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	adaptive immune response [GO:0002250]; B cell activation [GO:0042113]; beta selection [GO:0043366]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556]; negative thymic T cell selection [GO:0045060]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of T cell differentiation [GO:0045582]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; T cell activation [GO:0042110]; T cell aggregation [GO:0070489]; T cell differentiation [GO:0030217]; T cell migration [GO:0072678]; T cell receptor signaling pathway [GO:0050852]	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]	cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]
d1m66a2_d2naca1__1				Proteobacteria	glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycosome [GO:0020015]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]	cytoplasm [GO:0005737]; formate dehydrogenase (NAD+) activity [GO:0008863]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; formate catabolic process [GO:0042183]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]	formate catabolic process [GO:0042183]	glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycosome [GO:0020015]	cytoplasm [GO:0005737]	glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]	formate dehydrogenase (NAD+) activity [GO:0008863]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d1m67a2_d1f14a2__1		Metazoa		Chordata	glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycosome [GO:0020015]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycosome [GO:0020015]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d1m6bb2_d1o6sa2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; neuregulin binding [GO:0038132]; neuregulin receptor activity [GO:0038131]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activator activity [GO:0030296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; cranial nerve development [GO:0021545]; endocardial cushion development [GO:0003197]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; negative regulation of cell adhesion [GO:0007162]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of secretion [GO:0051048]; negative regulation of signal transduction [GO:0009968]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cardiac muscle tissue development [GO:0055025]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein tyrosine kinase activity [GO:0061098]; regulation of cell motility [GO:2000145]; regulation of cell population proliferation [GO:0042127]; Schwann cell differentiation [GO:0014037]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	cranial nerve development [GO:0021545]; endocardial cushion development [GO:0003197]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; negative regulation of cell adhesion [GO:0007162]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of secretion [GO:0051048]; negative regulation of signal transduction [GO:0009968]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cardiac muscle tissue development [GO:0055025]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein tyrosine kinase activity [GO:0061098]; regulation of cell motility [GO:2000145]; regulation of cell population proliferation [GO:0042127]; Schwann cell differentiation [GO:0014037]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; neuregulin binding [GO:0038132]; neuregulin receptor activity [GO:0038131]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activator activity [GO:0030296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1m6ca__d1or6b___1	Metazoa		Chordata	Firmicutes	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	membrane [GO:0016020]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; aerotaxis [GO:0009454]; signal transduction [GO:0007165]		aerotaxis [GO:0009454]; signal transduction [GO:0007165]		membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d1m6ha2_d1v3ub2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	cytoplasm [GO:0005737]; 13-prostaglandin reductase activity [GO:0036132]; 15-oxoprostaglandin 13-oxidase activity [GO:0047522]; 2-alkenal reductase [NAD(P)+] activity [GO:0032440]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]	13-prostaglandin reductase activity [GO:0036132]; 15-oxoprostaglandin 13-oxidase activity [GO:0047522]; 2-alkenal reductase [NAD(P)+] activity [GO:0032440]
d1m6hb2_d1udba___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]; carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]
d1m6ja__d1ml1e___1					triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]; glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1m6ma__d1yzia___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1m6mb__d1g0aa___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1m6ta__d2xlda___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1m6va2_d1wo8e___1			Proteobacteria	Deinococcus-Thermus	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	methylglyoxal synthase activity [GO:0008929]
d1m6va3_d5xi7f1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]; tubulin binding [GO:0015631]; microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	tubulin binding [GO:0015631]
d1m6va5_d2dlna2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1m6vc2_d2iu0b1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1m6vc4_d2r86b1__1			Proteobacteria	Euryarchaeota	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]
d1m6ve2_d1vmdb1__1			Proteobacteria	Thermotogae	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	methylglyoxal synthase activity [GO:0008929]
d1m6ve3_d2gpsa2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1m6ve4_d2w6pb1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1m6ve4_d5dmxa1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1m6ve5_d2yw2b2__1			Proteobacteria	Aquificae	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d1m6vg2_d1p4rb1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1m6wa2_d1pedc2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]
d1m6zd2_d5cieb___1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	periplasmic space [GO:0042597]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1m70b1_d2lita___1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	periplasmic space [GO:0042597]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1m70c1_d1etpb2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1m70c2_d1fcdc1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]
d1m71a1_d1i7za2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1m71a1_d2dqih___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1m73e__d4k6od___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]	metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]
d1m74a3_d1t5la1__1			Firmicutes	Firmicutes	cell envelope Sec protein transport complex [GO:0031522]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; ATPase-coupled protein transmembrane transporter activity [GO:0015462]; metal ion binding [GO:0046872]; intracellular protein transmembrane transport [GO:0065002]; protein import [GO:0017038]; protein targeting [GO:0006605]; protein transport by the Sec complex [GO:0043952]	cytoplasm [GO:0005737]; excinuclease repair complex [GO:0009380]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; excinuclease ABC activity [GO:0009381]; nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432]	intracellular protein transmembrane transport [GO:0065002]; protein import [GO:0017038]; protein targeting [GO:0006605]; protein transport by the Sec complex [GO:0043952]	nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432]	cell envelope Sec protein transport complex [GO:0031522]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]	cytoplasm [GO:0005737]; excinuclease repair complex [GO:0009380]	ATPase-coupled protein transmembrane transporter activity [GO:0015462]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; excinuclease ABC activity [GO:0009381]
d1m79a__d4m7ua1__1	Fungi		Ascomycota	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d1m79b__d1dr6a___1	Fungi	Metazoa	Ascomycota	Chordata	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d1m7aa__d3k47a___1	Fungi	Metazoa	Ascomycota	Chordata	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1m7aa__d4g3ma2__1	Fungi		Ascomycota	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	riboflavin biosynthetic process [GO:0009231]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d1m7ab__d2b3zd1__1	Fungi		Ascomycota	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	riboflavin biosynthetic process [GO:0009231]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d1m7ba__d1z08c___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell division site [GO:0032153]; cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901]; actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; Rho protein signal transduction [GO:0007266]	axon cytoplasm [GO:1904115]; cleavage furrow [GO:0032154]; cytoplasmic side of early endosome membrane [GO:0098559]; cytoplasmic side of plasma membrane [GO:0009898]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi cisterna membrane [GO:0032580]; synapse [GO:0045202]; trans-Golgi network [GO:0005802]; vesicle membrane [GO:0012506]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; anterograde axonal transport [GO:0008089]; intracellular protein transport [GO:0006886]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of receptor-mediated endocytosis [GO:0048260]; Rab protein signal transduction [GO:0032482]; regulation of axon extension [GO:0030516]; regulation of exocytosis [GO:0017157]	actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; Rho protein signal transduction [GO:0007266]	anterograde axonal transport [GO:0008089]; intracellular protein transport [GO:0006886]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of receptor-mediated endocytosis [GO:0048260]; Rab protein signal transduction [GO:0032482]; regulation of axon extension [GO:0030516]; regulation of exocytosis [GO:0017157]	cell cortex [GO:0005938]; cell division site [GO:0032153]; cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]	axon cytoplasm [GO:1904115]; cleavage furrow [GO:0032154]; cytoplasmic side of early endosome membrane [GO:0098559]; cytoplasmic side of plasma membrane [GO:0009898]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi cisterna membrane [GO:0032580]; synapse [GO:0045202]; trans-Golgi network [GO:0005802]; vesicle membrane [GO:0012506]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein kinase binding [GO:0019901]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1m7da1_d3gizl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1m7da2_d4kv5e___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; antigen binding [GO:0003823]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; aortic valve morphogenesis [GO:0003180]; ATP biosynthetic process [GO:0006754]; BMP signaling pathway [GO:0030509]; cell cycle arrest [GO:0007050]; cell development [GO:0048468]; cell migration [GO:0016477]; cell-cell junction organization [GO:0045216]; cellular response to organic cyclic compound [GO:0071407]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chondrocyte differentiation [GO:0002062]; common-partner SMAD protein phosphorylation [GO:0007182]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; embryonic liver development [GO:1990402]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial to mesenchymal transition [GO:0001837]; evasion or tolerance of host defenses by virus [GO:0019049]; extracellular matrix assembly [GO:0085029]; extrinsic apoptotic signaling pathway [GO:0097191]; heart development [GO:0007507]; heart valve morphogenesis [GO:0003179]; hematopoietic progenitor cell differentiation [GO:0002244]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymph node development [GO:0048535]; macrophage derived foam cell differentiation [GO:0010742]; MAPK cascade [GO:0000165]; membrane protein intracellular domain proteolysis [GO:0031293]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cytolysis [GO:0045918]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of skeletal muscle tissue development [GO:0048642]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; ossification involved in bone remodeling [GO:0043932]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; phosphate-containing compound metabolic process [GO:0006796]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of chemotaxis [GO:0050921]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglia differentiation [GO:0014008]; positive regulation of NAD+ ADP-ribosyltransferase activity [GO:1901666]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular permeability [GO:0043117]; protein export from nucleus [GO:0006611]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor catabolic process [GO:0032801]; regulation of apoptotic process [GO:0042981]; regulation of binding [GO:0051098]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of DNA binding [GO:0051101]; regulation of MAPK cascade [GO:0043408]; regulation of protein import into nucleus [GO:0042306]; regulation of SMAD protein signal transduction [GO:0060390]; regulation of striated muscle tissue development [GO:0016202]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; salivary gland morphogenesis [GO:0007435]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transforming growth factor beta receptor signaling pathway involved in heart development [GO:1905313]; vasculogenesis [GO:0001570]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	aortic valve morphogenesis [GO:0003180]; ATP biosynthetic process [GO:0006754]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell cycle arrest [GO:0007050]; cell development [GO:0048468]; cell migration [GO:0016477]; cellular response to organic cyclic compound [GO:0071407]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chondrocyte differentiation [GO:0002062]; common-partner SMAD protein phosphorylation [GO:0007182]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; embryonic liver development [GO:1990402]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial to mesenchymal transition [GO:0001837]; evasion or tolerance of host defenses by virus [GO:0019049]; extracellular matrix assembly [GO:0085029]; extrinsic apoptotic signaling pathway [GO:0097191]; heart development [GO:0007507]; heart valve morphogenesis [GO:0003179]; hematopoietic progenitor cell differentiation [GO:0002244]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymph node development [GO:0048535]; macrophage derived foam cell differentiation [GO:0010742]; MAPK cascade [GO:0000165]; membrane protein intracellular domain proteolysis [GO:0031293]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytolysis [GO:0045918]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of skeletal muscle tissue development [GO:0048642]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; ossification involved in bone remodeling [GO:0043932]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; phosphate-containing compound metabolic process [GO:0006796]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of chemotaxis [GO:0050921]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglia differentiation [GO:0014008]; positive regulation of NAD+ ADP-ribosyltransferase activity [GO:1901666]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular permeability [GO:0043117]; protein export from nucleus [GO:0006611]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor catabolic process [GO:0032801]; regulation of apoptotic process [GO:0042981]; regulation of binding [GO:0051098]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of DNA binding [GO:0051101]; regulation of MAPK cascade [GO:0043408]; regulation of protein import into nucleus [GO:0042306]; regulation of SMAD protein signal transduction [GO:0060390]; regulation of striated muscle tissue development [GO:0016202]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; salivary gland morphogenesis [GO:0007435]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transforming growth factor beta receptor signaling pathway involved in heart development [GO:1905313]; vasculogenesis [GO:0001570]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]
d1m7ea__d4haub___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; clathrin coat of coated pit [GO:0030132]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]; activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	apical plasma membrane [GO:0016324]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol binding [GO:0035091]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1m7eb__d1fhwb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; clathrin coat of coated pit [GO:0030132]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]; activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; establishment of epithelial cell polarity [GO:0090162]; Golgi vesicle transport [GO:0048193]; positive regulation of cell adhesion [GO:0045785]; regulation of ARF protein signal transduction [GO:0032012]	activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	establishment of epithelial cell polarity [GO:0090162]; Golgi vesicle transport [GO:0048193]; positive regulation of cell adhesion [GO:0045785]; regulation of ARF protein signal transduction [GO:0032012]	apical plasma membrane [GO:0016324]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle [GO:0001726]	AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol binding [GO:0035091]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]
d1m7ia1_d5b3jl2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; NMDA selective glutamate receptor complex [GO:0017146]; postsynaptic membrane [GO:0045211]; metal ion binding [GO:0046872]; NMDA glutamate receptor activity [GO:0004972]; protein heterotetramerization [GO:0051290]; response to zinc ion [GO:0010043]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	protein heterotetramerization [GO:0051290]; response to zinc ion [GO:0010043]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; NMDA selective glutamate receptor complex [GO:0017146]; postsynaptic membrane [GO:0045211]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]; NMDA glutamate receptor activity [GO:0004972]
d1m7ib2_d5wccb2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1m7ra2_d1kava___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]; identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1m7rb1_d4ny0d3__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]; identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]	identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]
d1m7xa1_d1izja1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]	extracellular region [GO:0005576]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1m7xb2_d1vfma2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]		1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1m80a3_d1crkb1__1		Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; phosphocreatine biosynthetic process [GO:0046314]		phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d1m83a__d2d54a2__1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; methionyl-tRNA aminoacylation [GO:0006431]	tryptophanyl-tRNA aminoacylation [GO:0006436]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]
d1m8ka1_d1s4ma2__1			Euryarchaeota	Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; NAD biosynthetic process [GO:0009435]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]; FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	NAD biosynthetic process [GO:0009435]	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]
d1m8ka1_d2quja2__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; kinase inhibitor activity [GO:0019210]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tryptophan-tRNA ligase activity [GO:0004830]; angiogenesis [GO:0001525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; regulation of angiogenesis [GO:0045765]; regulation of protein ADP-ribosylation [GO:0010835]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]	NAD biosynthetic process [GO:0009435]	angiogenesis [GO:0001525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; regulation of angiogenesis [GO:0045765]; regulation of protein ADP-ribosylation [GO:0010835]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]	ATP binding [GO:0005524]; kinase inhibitor activity [GO:0019210]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tryptophan-tRNA ligase activity [GO:0004830]
d1m8kb1_d1u7xa___1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	NAD biosynthetic process [GO:0009435]	tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]
d1m8kc1_d3lcja___1			Euryarchaeota	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	NAD biosynthetic process [GO:0009435]	coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1m8pb2_d1gtra2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]
d1m8pc3_d1svlb___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]
d1m8ua1_d3hz2d___1	Metazoa		Chordata	Euryarchaeota	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1m8ua2_d3so0g___1	Metazoa		Chordata	Firmicutes	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1m8vc__d1n9ra___1		Fungi	Euryarchaeota	Ascomycota		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]
d1m8ve__d4m78j___1		Fungi	Euryarchaeota	Ascomycota		Lsm1-7-Pat1 complex [GO:1990726]; nucleolus [GO:0005730]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]		maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]		Lsm1-7-Pat1 complex [GO:1990726]; nucleolus [GO:0005730]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]		RNA binding [GO:0003723]
d1m8vg__d1i4kt___1			Euryarchaeota	Euryarchaeota								
d1m8vh__d4f7uh___1		Metazoa	Euryarchaeota	Chordata		catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; RNA binding [GO:0003723]; U1 snRNP binding [GO:1990446]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]		import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]		catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]		RNA binding [GO:0003723]; U1 snRNP binding [GO:1990446]
d1m8vj__d1th7j2__1			Euryarchaeota	Crenarchaeota								
d1m8vk__d3jcmj___1		Fungi	Euryarchaeota	Ascomycota		catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]; generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]		generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]		catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]
d1m8vl__d3s6nf___1			Euryarchaeota									
d1m8vm__d1vu3d___1			Euryarchaeota									
d1m90d__d4pc6a2__1			Euryarchaeota	Proteobacteria	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	translation [GO:0006412]		ribosome [GO:0005840]	cytoplasm [GO:0005737]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1m90g1_d1m90g2__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1m90o__d2qbbk1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1m94a__d2zjdc___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein tag [GO:0031386]; cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; mRNA splicing, via spliceosome [GO:0000398]; post-translational protein modification [GO:0043687]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; mRNA splicing, via spliceosome [GO:0000398]; post-translational protein modification [GO:0043687]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	protein tag [GO:0031386]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d1m99a1_d4ecib2__1	Metazoa		Platyhelminthes	Proteobacteria	glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]					glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d1m99a1_d5d73a2__1	Metazoa	Metazoa	Platyhelminthes	Nematoda (roundworms)	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]					glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1m9aa2_d1gule2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1m9ba1_d3zmla2__1	Metazoa	Metazoa	Platyhelminthes	Arthropoda	glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]					glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d1m9ca__d2r99a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; U2-type catalytic step 2 spliceosome [GO:0071007]; cyclosporin A binding [GO:0016018]; mRNA binding [GO:0003729]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; mRNA splicing, via spliceosome [GO:0000398]; neutrophil degranulation [GO:0043312]; positive regulation of viral genome replication [GO:0045070]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	mRNA splicing, via spliceosome [GO:0000398]; neutrophil degranulation [GO:0043312]; positive regulation of viral genome replication [GO:0045070]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; U2-type catalytic step 2 spliceosome [GO:0071007]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	cyclosporin A binding [GO:0016018]; mRNA binding [GO:0003729]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]
d1m9dd__d2xgva___1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]		entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	
d1m9ga__d3q2pb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta								
d1m9na1_d1a9xg2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1m9na2_d5tkma___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]	'de novo' IMP biosynthetic process [GO:0006189]	cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1m9pb__d4lmxh___1	Metazoa		Chordata	Cryptophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast [GO:0009507]; phycobilisome [GO:0030089]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	chloroplast [GO:0009507]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1m9pc__d3uhda___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1m9sa1_d1v3ma1__1			Firmicutes	Firmicutes	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1m9sa1_d2omwa1__1		Metazoa	Firmicutes	Chordata	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	pathogenesis [GO:0009405]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d1m9ub__d2p3fh___1	Metazoa	Metazoa	Annelida	Chordata	kinase activity [GO:0016301]; serine-type endopeptidase activity [GO:0004252]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	kinase activity [GO:0016301]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1m9wa__d1m56h1__1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]			thylakoid membrane [GO:0042651]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1m9xg__d3h4ea1__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1m9xh__d4ph2a___1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	viral nucleocapsid [GO:0019013]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ma0a2_d1x7hb___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	antibiotic biosynthetic process [GO:0017000]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]	oxidoreductase activity [GO:0016491]
d1ma0b2_d5h5xk___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1ma1a1_d4l2bb1__1			Euryarchaeota	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ma1b1_d3ak1a1__1			Euryarchaeota	Crenarchaeota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ma1b2_d4f2nb2__1			Euryarchaeota		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ma1c1_d3lj9b1__1			Euryarchaeota	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ma1d2_d3js4b2__1			Euryarchaeota	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ma1e1_d1ap5a1__1		Metazoa	Euryarchaeota	Chordata	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ma1e2_d4yeta2__1			Euryarchaeota	Apicomplexa	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ma1f1_d1i08a1__1			Euryarchaeota	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ma1f1_d5tira1__1		Fungi	Euryarchaeota	Ascomycota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ma1f2_d4gunh2__1		Fungi	Euryarchaeota	Ascomycota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1maad__d4zwnb1__1	Metazoa	Fungi	Chordata	Ascomycota	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]; acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; acylglycerol lipase activity [GO:0047372]; serine hydrolase activity [GO:0017171]; triglyceride catabolic process [GO:0019433]; triglyceride metabolic process [GO:0006641]	acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	triglyceride catabolic process [GO:0019433]; triglyceride metabolic process [GO:0006641]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]	cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]	acylglycerol lipase activity [GO:0047372]; serine hydrolase activity [GO:0017171]
d1mabb1_d3a5cn3__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial envelope [GO:0005740]; mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP biosynthetic process [GO:0006754]; ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; cellular response to nitric oxide [GO:0071732]; oxidative phosphorylation [GO:0006119]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP biosynthetic process [GO:0006754]; ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; cellular response to nitric oxide [GO:0071732]; oxidative phosphorylation [GO:0006119]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial envelope [GO:0005740]; mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1mabb2_d2jj1a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial envelope [GO:0005740]; mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP biosynthetic process [GO:0006754]; ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; cellular response to nitric oxide [GO:0071732]; oxidative phosphorylation [GO:0006119]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP biosynthetic process [GO:0006754]; ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; cellular response to nitric oxide [GO:0071732]; oxidative phosphorylation [GO:0006119]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial envelope [GO:0005740]; mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1maca__d1qu0a___1		Metazoa	Firmicutes	Chordata	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	carbohydrate metabolic process [GO:0005975]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]		basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	licheninase activity [GO:0042972]	signaling receptor binding [GO:0005102]
d1maca__d3i4ia___1			Firmicutes		licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			licheninase activity [GO:0042972]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1maeh__d2gc7i___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]; methylamine metabolic process [GO:0030416]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	methylamine metabolic process [GO:0030416]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1maka__d4i9wd2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]; identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]; cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]	antigen binding [GO:0003823]	identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]
d1mamh1_d1ruah2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	metal ion binding [GO:0046872]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d1maml2_d1kira___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1maml2_d5fehc2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1mata__d3mata___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]	cytosol [GO:0005829]	ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]	ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]
d1mawa__d5o06b___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	tryptophanyl-tRNA aminoacylation [GO:0006436]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1mawb__d1t6xa2__1			Firmicutes	Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]; FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	tryptophanyl-tRNA aminoacylation [GO:0006436]	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]
d1mawd__d5bnzb1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	tryptophanyl-tRNA aminoacylation [GO:0006436]	glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]
d1mawf__d4qrda1__1			Firmicutes		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]		tryptophanyl-tRNA aminoacylation [GO:0006436]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	
d1maya__d3e0nb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; sodium channel regulator activity [GO:0017080]; cornification [GO:0070268]; positive regulation of sodium ion transport [GO:0010765]	digestion [GO:0007586]; proteolysis [GO:0006508]	cornification [GO:0070268]; positive regulation of sodium ion transport [GO:0010765]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; sodium channel regulator activity [GO:0017080]
d1mb2d__d2dxia2__1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	tryptophanyl-tRNA aminoacylation [GO:0006436]	glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1mb2e__d1n2hb___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]; beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	tryptophanyl-tRNA aminoacylation [GO:0006436]	beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]
d1mb4a2_d1nwcb2__1			Proteobacteria	Proteobacteria	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]			aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]
d1mb4b2_d1e5qa2__1		Fungi	Proteobacteria	Ascomycota	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	lysine biosynthetic process via aminoadipic acid [GO:0019878]			aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]
d1mb8a2_d3hopa2__1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d1mbaa__d5fvbl___1	Metazoa		Mollusca	Cyanobacteria	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1mbca__d2uune___1	Metazoa		Chordata		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1mbia__d1b33h___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1mbmd__d1kxba___1					host cell membrane [GO:0033644]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]
d1mbud__d1dd3b2__1			Proteobacteria	Thermotogae	chaperone binding [GO:0051087]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytosolic large ribosomal subunit [GO:0022625]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]	chaperone binding [GO:0051087]	structural constituent of ribosome [GO:0003735]
d1mbud__d3g19a___1			Proteobacteria	Proteobacteria	chaperone binding [GO:0051087]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]			chaperone binding [GO:0051087]	
d1mbvb__d2bcwb1__1			Proteobacteria	Proteobacteria	chaperone binding [GO:0051087]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; large ribosomal subunit [GO:0015934]; protein homodimerization activity [GO:0042803]; ribosome binding [GO:0043022]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	translation [GO:0006412]		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; large ribosomal subunit [GO:0015934]	chaperone binding [GO:0051087]	protein homodimerization activity [GO:0042803]; ribosome binding [GO:0043022]; structural constituent of ribosome [GO:0003735]
d1mbxc__d4yjmd___1			Proteobacteria	Proteobacteria	chaperone binding [GO:0051087]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]			chaperone binding [GO:0051087]	
d1mbxd__d3gq1b___1			Proteobacteria	Proteobacteria	chaperone binding [GO:0051087]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]			chaperone binding [GO:0051087]	
d1mc0a1_d3ksia___1	Metazoa		Chordata		axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber [GO:0097457]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic membrane [GO:0097060]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; GAF domain binding [GO:0036004]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cardiac septum development [GO:0003279]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; coronary vasculature development [GO:0060976]; establishment of endothelial barrier [GO:0061028]; heart development [GO:0007507]; heart valve development [GO:0003170]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cell death [GO:0060548]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; regulation of nitric oxide mediated signal transduction [GO:0010749]; ventricular septum development [GO:0003281]		adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cardiac septum development [GO:0003279]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; coronary vasculature development [GO:0060976]; establishment of endothelial barrier [GO:0061028]; heart development [GO:0007507]; heart valve development [GO:0003170]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cell death [GO:0060548]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; regulation of nitric oxide mediated signal transduction [GO:0010749]; ventricular septum development [GO:0003281]		axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber [GO:0097457]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic membrane [GO:0097060]		3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; GAF domain binding [GO:0036004]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]	
d1mc1b2_d1g4ac___1			Actinobacteria	Proteobacteria	(carboxyethyl)arginine beta-lactam-synthase activity [GO:0034027]; asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; asparagine biosynthetic process [GO:0006529]; clavulanic acid biosynthetic process [GO:0033050]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	asparagine biosynthetic process [GO:0006529]; clavulanic acid biosynthetic process [GO:0033050]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]		cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	(carboxyethyl)arginine beta-lactam-synthase activity [GO:0034027]; asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]
d1mc5a2_d1hyea1__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]	L-lactate dehydrogenase activity [GO:0004459]
d1mc7a__d4nmtb___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; Rac GTPase binding [GO:0048365]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; collateral sprouting [GO:0048668]; convergent extension involved in neural plate elongation [GO:0022007]; convergent extension involved in organogenesis [GO:0060029]; cytoplasmic microtubule organization [GO:0031122]; dendrite morphogenesis [GO:0048813]; dendritic spine morphogenesis [GO:0060997]; intracellular signal transduction [GO:0035556]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse organization [GO:0099173]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein localization to microtubule [GO:0035372]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cellular protein localization [GO:1903827]; regulation of neurotransmitter levels [GO:0001505]; regulation of protein phosphorylation [GO:0001932]; regulation of synaptic vesicle exocytosis [GO:2000300]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; social behavior [GO:0035176]; synapse organization [GO:0050808]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	axon extension [GO:0048675]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; collateral sprouting [GO:0048668]; convergent extension involved in neural plate elongation [GO:0022007]; convergent extension involved in organogenesis [GO:0060029]; cytoplasmic microtubule organization [GO:0031122]; dendrite morphogenesis [GO:0048813]; dendritic spine morphogenesis [GO:0060997]; intracellular signal transduction [GO:0035556]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse organization [GO:0099173]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein localization to microtubule [GO:0035372]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cellular protein localization [GO:1903827]; regulation of neurotransmitter levels [GO:0001505]; regulation of protein phosphorylation [GO:0001932]; regulation of synaptic vesicle exocytosis [GO:2000300]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; social behavior [GO:0035176]; synapse organization [GO:0050808]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; Rac GTPase binding [GO:0048365]	ion channel binding [GO:0044325]
d1mc8a1_d4wa8a2__1			Euryarchaeota	Euryarchaeota	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]			5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]
d1mc8b2_d2bsqb1__1			Euryarchaeota	Proteobacteria	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]; migration in host [GO:0044001]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	migration in host [GO:0044001]			5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]
d1mcba1_d4rgol1__1	Metazoa		Chordata	Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1mcba2_d3d9al1__1	Metazoa	Metazoa	Chordata	Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1mcbb1_d1gpoh1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1mcbb1_d3v7ma2__1	Metazoa	Metazoa	Chordata	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1mcbb2_d1i1ac1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]		
d1mcca1_d4ygah___1				Apicomplexa		ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; protein kinase activity [GO:0004672]						ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; protein kinase activity [GO:0004672]
d1mcca2_d1ya5b1__1		Metazoa		Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1mcda2_d2vxql1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1mcdb1_d1wipb3__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1mcea2_d5e56a___1		Metazoa		Chordata		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]		
d1mcha2_d5fyju___1	Metazoa		Chordata			host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1mchb1_d4xpal2__1	Metazoa	Metazoa	Chordata	Arthropoda		integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]; adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]		adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]		integral component of plasma membrane [GO:0005887]; neuronal cell body membrane [GO:0032809]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]		cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]
d1mchb2_d1hxmh2__1	Metazoa	Metazoa	Chordata	Chordata		integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]		adaptive immune response [GO:0002250]; immune response [GO:0006955]		integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]		transmembrane signaling receptor activity [GO:0004888]
d1mcia1_d4y5xk1__1		Metazoa		Chordata		extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]		brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]		extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]		erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]
d1mcib1_d2ny3c2__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1mcja1_d4g7vl2__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; ion channel activity [GO:0005216]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; phosphatidylinositol dephosphorylation [GO:0046856]		phosphatidylinositol dephosphorylation [GO:0046856]		integral component of membrane [GO:0016021]		ion channel activity [GO:0005216]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1mcja2_d4i77l1__1		Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]
d1mcjb1_d2q87b1__1		Metazoa		Chordata		extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; phosphatidylethanolamine binding [GO:0008429]; phosphatidylserine binding [GO:0001786]; signaling receptor activity [GO:0038023]; cell adhesion [GO:0007155]; negative regulation of activation of Janus kinase activity [GO:1902569]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of eosinophil activation [GO:1902567]; negative regulation of eosinophil migration [GO:2000417]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mast cell activation involved in immune response [GO:0033007]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034125]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of NK T cell activation [GO:0051134]; negative regulation of phagocytosis, engulfment [GO:0060101]; neutrophil degranulation [GO:0043312]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; regulation of immune response [GO:0050776]; regulation of T cell receptor signaling pathway [GO:0050856]		cell adhesion [GO:0007155]; negative regulation of activation of Janus kinase activity [GO:1902569]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of eosinophil activation [GO:1902567]; negative regulation of eosinophil migration [GO:2000417]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mast cell activation involved in immune response [GO:0033007]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034125]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of NK T cell activation [GO:0051134]; negative regulation of phagocytosis, engulfment [GO:0060101]; neutrophil degranulation [GO:0043312]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; regulation of immune response [GO:0050776]; regulation of T cell receptor signaling pathway [GO:0050856]		extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]		phosphatidylethanolamine binding [GO:0008429]; phosphatidylserine binding [GO:0001786]; signaling receptor activity [GO:0038023]
d1mcka1_d1hi6b1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1mcka1_d3mugc1__1												
d1mcla1_d1ct8b1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1mcna2_d3fjtb1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1mcna2_d5y32a2__1		Metazoa		Chordata		glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of presynaptic membrane [GO:0099056]; Schaffer collateral - CA1 synapse [GO:0098685]; cell adhesion molecule binding [GO:0050839]; protein tyrosine phosphatase activity [GO:0004725]; signaling receptor binding [GO:0005102]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]		heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of immune response [GO:0050776]; regulation of postsynaptic density assembly [GO:0099151]; synaptic membrane adhesion [GO:0099560]		glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of presynaptic membrane [GO:0099056]; Schaffer collateral - CA1 synapse [GO:0098685]		cell adhesion molecule binding [GO:0050839]; protein tyrosine phosphatase activity [GO:0004725]; signaling receptor binding [GO:0005102]
d1mcnb1_d4r4bl2__1												
d1mcnb2_d1f3dl1__1		Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d1mcoh2_d2a6dh3__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1mcoh3_d3pgfl2__1				Proteobacteria		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1mcoh4_d1dclb1__1		Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d1mcol2_d2fjfu2__1												
d1mcph1_d3bd5b___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1mcph1_d5xxyl2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1mcph2_d1fe8n1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1mcph2_d1l7sh4__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1mcpl1_d5c3ld1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	nuclear pore [GO:0005643]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	nuclear pore [GO:0005643]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1mcqa2_d1legb___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1mcqa2_d2arjh1__1		Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]		cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]		identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]
d1mcra2_d4x6de1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1mcrb2_d5tf1l2__1												
d1mcsa1_d1m4ka2__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; transmembrane signaling receptor activity [GO:0004888]; immune response [GO:0006955]; innate immune response [GO:0045087]; regulation of immune response [GO:0050776]		immune response [GO:0006955]; innate immune response [GO:0045087]; regulation of immune response [GO:0050776]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		transmembrane signaling receptor activity [GO:0004888]
d1mcta__d2pfeb___1	Metazoa		Chordata	Actinobacteria	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1mcue__d5tcaf___1		Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]		complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]		serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1mcwm1_d3gjel1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]	
d1mcwm2_d2ak4n1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1mcww1_d1kj2d___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1mcxa__d1yj0a___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytoplasmic vesicle membrane [GO:0030659]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of endosome membrane [GO:0031313]; extrinsic component of external side of plasma membrane [GO:0031232]; lateral plasma membrane [GO:0016328]; motile cilium [GO:0031514]; nucleus [GO:0005634]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; phospholipase A2 inhibitor activity [GO:0019834]; actin cytoskeleton reorganization [GO:0031532]; adaptive immune response [GO:0002250]; alpha-beta T cell differentiation [GO:0046632]; arachidonic acid secretion [GO:0050482]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; DNA duplex unwinding [GO:0032508]; endocrine pancreas development [GO:0031018]; estrous cycle [GO:0044849]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gliogenesis [GO:0042063]; granulocyte chemotaxis [GO:0071621]; hepatocyte differentiation [GO:0070365]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; insulin secretion [GO:0030073]; keratinocyte differentiation [GO:0030216]; monocyte chemotaxis [GO:0002548]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of exocytosis [GO:0045920]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; neutrophil clearance [GO:0097350]; phagocytosis [GO:0006909]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; positive regulation of vesicle fusion [GO:0031340]; positive regulation of wound healing [GO:0090303]; prolactin secretion [GO:0070459]; prostate gland development [GO:0030850]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of hormone secretion [GO:0046883]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-1 production [GO:0032652]; regulation of leukocyte migration [GO:0002685]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to interleukin-1 [GO:0070555]; response to peptide hormone [GO:0043434]; response to X-ray [GO:0010165]	calcium channel complex [GO:0034704]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; vesicle [GO:0031982]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]; calcium ion homeostasis [GO:0055074]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	actin cytoskeleton reorganization [GO:0031532]; adaptive immune response [GO:0002250]; alpha-beta T cell differentiation [GO:0046632]; arachidonic acid secretion [GO:0050482]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; DNA duplex unwinding [GO:0032508]; endocrine pancreas development [GO:0031018]; estrous cycle [GO:0044849]; gliogenesis [GO:0042063]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; granulocyte chemotaxis [GO:0071621]; hepatocyte differentiation [GO:0070365]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; insulin secretion [GO:0030073]; keratinocyte differentiation [GO:0030216]; monocyte chemotaxis [GO:0002548]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of exocytosis [GO:0045920]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; neutrophil clearance [GO:0097350]; phagocytosis [GO:0006909]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; positive regulation of vesicle fusion [GO:0031340]; positive regulation of wound healing [GO:0090303]; prolactin secretion [GO:0070459]; prostate gland development [GO:0030850]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of hormone secretion [GO:0046883]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-1 production [GO:0032652]; regulation of leukocyte migration [GO:0002685]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to interleukin-1 [GO:0070555]; response to peptide hormone [GO:0043434]; response to X-ray [GO:0010165]	calcium ion homeostasis [GO:0055074]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytoplasmic vesicle membrane [GO:0030659]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of endosome membrane [GO:0031313]; extrinsic component of external side of plasma membrane [GO:0031232]; lateral plasma membrane [GO:0016328]; motile cilium [GO:0031514]; nucleus [GO:0005634]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]	calcium channel complex [GO:0034704]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; membrane [GO:0016020]; vesicle [GO:0031982]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; phospholipase A2 inhibitor activity [GO:0019834]	calcium channel activity [GO:0005262]; calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]
d1mczb3_d3dv0h1__1			Proteobacteria	Firmicutes	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	mandelate catabolic process [GO:0019596]	glycolytic process [GO:0006096]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1mczc2_d2vk1d1__1		Fungi	Proteobacteria	Ascomycota	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	mandelate catabolic process [GO:0019596]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1mczd1_d2vk1c2__1		Fungi	Proteobacteria	Ascomycota	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	mandelate catabolic process [GO:0019596]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1mczd2_d2jiba2__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	mandelate catabolic process [GO:0019596]	oxalate catabolic process [GO:0033611]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d1mczf3_d2wvaa1__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1mczg1_d1efpc2__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	electron transfer activity [GO:0009055]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	electron transfer activity [GO:0009055]
d1mczg3_d5dgta1__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	mandelate catabolic process [GO:0019596]	mandelate catabolic process [GO:0019596]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1mczh1_d2ihvc2__1			Proteobacteria	Actinobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]
d1mczh3_d2wvhz1__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1mczh3_d5imsb3__1		Fungi	Proteobacteria	Ascomycota	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mandelate catabolic process [GO:0019596]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1mczi3_d1gpua2__1		Fungi	Proteobacteria	Ascomycota	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	mandelate catabolic process [GO:0019596]	pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1mczj2_d1tkca2__1		Fungi	Proteobacteria	Ascomycota	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	mandelate catabolic process [GO:0019596]	pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1mczj2_d1zpda2__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1mczj3_d1upbc3__1			Proteobacteria	Actinobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]
d1mczj3_d3exgp1__1		Metazoa	Proteobacteria	Chordata	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	mandelate catabolic process [GO:0019596]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1mczk1_d1icib___1			Proteobacteria	Euryarchaeota	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	mandelate catabolic process [GO:0019596]			cytoplasm [GO:0005737]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d1mczk3_d1w85g___1			Proteobacteria	Firmicutes	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	mandelate catabolic process [GO:0019596]	glycolytic process [GO:0006096]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1mczl3_d2ji9b3__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	mandelate catabolic process [GO:0019596]	oxalate catabolic process [GO:0033611]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d1mczl3_d4zp1c3__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1mczm1_d5mara1__1		Metazoa	Proteobacteria	Chordata	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	centriole [GO:0005814]; centrosome [GO:0005813]; chromatin silencing complex [GO:0005677]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glial cell projection [GO:0097386]; growth cone [GO:0030426]; juxtaparanode region of axon [GO:0044224]; lateral loop [GO:0043219]; meiotic spindle [GO:0072687]; microtubule [GO:0005874]; midbody [GO:0030496]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; myelin sheath [GO:0043209]; nuclear heterochromatin [GO:0005720]; nucleolus [GO:0005730]; nucleus [GO:0005634]; paranodal junction [GO:0033010]; paranode region of axon [GO:0033270]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; Schmidt-Lanterman incisure [GO:0043220]; spindle [GO:0005819]; chromatin binding [GO:0003682]; histone acetyltransferase binding [GO:0035035]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone deacetylase activity (H4-K16 specific) [GO:0046970]; NAD-dependent protein deacetylase activity [GO:0034979]; protein deacetylase activity [GO:0033558]; transcription factor binding [GO:0008134]; tubulin deacetylase activity [GO:0042903]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; cell division [GO:0051301]; cellular lipid catabolic process [GO:0044242]; cellular response to caloric restriction [GO:0061433]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to oxidative stress [GO:0034599]; chromatin silencing [GO:0006342]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at telomere [GO:0006348]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; innate immune response [GO:0045087]; meiotic cell cycle [GO:0051321]; myelination in peripheral nervous system [GO:0022011]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine deacetylation [GO:0034983]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of cell division [GO:0051781]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]; protein kinase B signaling [GO:0043491]; regulation of cell cycle [GO:0051726]; regulation of exit from mitosis [GO:0007096]; regulation of myelination [GO:0031641]; regulation of phosphorylation [GO:0042325]; response to redox state [GO:0051775]; substantia nigra development [GO:0021762]; tubulin deacetylation [GO:0090042]	mandelate catabolic process [GO:0019596]	autophagy [GO:0006914]; cell division [GO:0051301]; cellular lipid catabolic process [GO:0044242]; cellular response to caloric restriction [GO:0061433]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to oxidative stress [GO:0034599]; chromatin silencing [GO:0006342]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at telomere [GO:0006348]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; innate immune response [GO:0045087]; meiotic cell cycle [GO:0051321]; myelination in peripheral nervous system [GO:0022011]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; peptidyl-lysine deacetylation [GO:0034983]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of cell division [GO:0051781]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]; protein kinase B signaling [GO:0043491]; regulation of cell cycle [GO:0051726]; regulation of exit from mitosis [GO:0007096]; regulation of myelination [GO:0031641]; regulation of phosphorylation [GO:0042325]; response to redox state [GO:0051775]; substantia nigra development [GO:0021762]; tubulin deacetylation [GO:0090042]		centriole [GO:0005814]; centrosome [GO:0005813]; chromatin silencing complex [GO:0005677]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glial cell projection [GO:0097386]; growth cone [GO:0030426]; juxtaparanode region of axon [GO:0044224]; lateral loop [GO:0043219]; meiotic spindle [GO:0072687]; microtubule [GO:0005874]; midbody [GO:0030496]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; myelin sheath [GO:0043209]; nuclear heterochromatin [GO:0005720]; nucleolus [GO:0005730]; nucleus [GO:0005634]; paranodal junction [GO:0033010]; paranode region of axon [GO:0033270]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; Schmidt-Lanterman incisure [GO:0043220]; spindle [GO:0005819]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	chromatin binding [GO:0003682]; histone acetyltransferase binding [GO:0035035]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone deacetylase activity (H4-K16 specific) [GO:0046970]; NAD-dependent protein deacetylase activity [GO:0034979]; protein deacetylase activity [GO:0033558]; transcription factor binding [GO:0008134]; tubulin deacetylase activity [GO:0042903]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270]
d1mczm3_d2r5na2__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	mandelate catabolic process [GO:0019596]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d1mczn1_d2wvgb2__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1mczn2_d1ngsb2__1		Fungi	Proteobacteria	Ascomycota	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	mandelate catabolic process [GO:0019596]	pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1mczn3_d2wvab3__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1mczo2_d5fema3__1		Fungi	Proteobacteria	Ascomycota	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mandelate catabolic process [GO:0019596]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1mczo3_d1ozhb3__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; butanediol metabolic process [GO:0034077]	mandelate catabolic process [GO:0019596]	butanediol metabolic process [GO:0034077]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1mczp1_d3riya1__1		Metazoa	Proteobacteria	Chordata	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	mandelate catabolic process [GO:0019596]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1mczp2_d5tmab1__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1md0a__d5e8gb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune system process [GO:0002376]; negative regulation of cell cycle [GO:0045786]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; animal organ morphogenesis [GO:0009887]; blood circulation [GO:0008015]; cell differentiation [GO:0030154]; hemostasis [GO:0007599]; megakaryocyte development [GO:0035855]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune system process [GO:0002376]; negative regulation of cell cycle [GO:0045786]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	animal organ morphogenesis [GO:0009887]; blood circulation [GO:0008015]; cell differentiation [GO:0030154]; hemostasis [GO:0007599]; megakaryocyte development [GO:0035855]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d1md0b__d5e8gd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune system process [GO:0002376]; negative regulation of cell cycle [GO:0045786]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; animal organ morphogenesis [GO:0009887]; blood circulation [GO:0008015]; cell differentiation [GO:0030154]; hemostasis [GO:0007599]; megakaryocyte development [GO:0035855]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune system process [GO:0002376]; negative regulation of cell cycle [GO:0045786]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	animal organ morphogenesis [GO:0009887]; blood circulation [GO:0008015]; cell differentiation [GO:0030154]; hemostasis [GO:0007599]; megakaryocyte development [GO:0035855]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d1md3a1_d1yj6c1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d1md3a1_d5eche2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1md4a1_d5echc2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1md4a2_d1k3lb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1md4b2_d5agya1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d1mdaa__d2bo0a2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1mdaj__d3pxtf___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	outer membrane-bounded periplasmic space [GO:0030288]; amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]; amine metabolic process [GO:0009308]		amine metabolic process [GO:0009308]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]
d1mdca__d4ycea___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	lipid binding [GO:0008289]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1mdia__d2pukc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; chloroplast [GO:0009507]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]; chloroplast [GO:0009507]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	protein disulfide oxidoreductase activity [GO:0015035]
d1mdja__d2gzya___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1mdta2_d1r45a___1					clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]		pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]	transferase activity, transferring pentosyl groups [GO:0016763]
d1mdua__d4s10c___1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1mdud__d2fghb1__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d1me3a__d1bp4a___1		Viridiplantae		Streptophyta	cysteine-type endopeptidase activity [GO:0004197]	cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]					cysteine-type endopeptidase activity [GO:0004197]	cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]
d1me6a__d1ebzb___1			Apicomplexa		vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1me6b__d1fg8d___1			Apicomplexa		vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1mec.1_d1yc6y___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1melb__d4xphl1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]; adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	integral component of plasma membrane [GO:0005887]; neuronal cell body membrane [GO:0032809]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]
d1mema__d4bpvd___1	Metazoa	Metazoa	Chordata	Chordata	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]
d1mepb__d2rted___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1merb__d5oyya___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1mesb__d3s85d___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1meta__d2igya___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1meta__d3ufnb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1metb__d4fl8a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1meub__d2rkfb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]
d1meub__d5p2va___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1mexl1_d3c5zh1__1		Metazoa		Chordata		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d1mexl2_d4k07h___1		Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d1meza__d2dfna___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; actin filament binding [GO:0051015]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; 'de novo' AMP biosynthetic process [GO:0044208]; AMP biosynthetic process [GO:0006167]; aspartate metabolic process [GO:0006531]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; glutamine metabolic process [GO:0006541]; IMP metabolic process [GO:0046040]; purine nucleotide metabolic process [GO:0006163]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to muscle activity [GO:0014850]; response to starvation [GO:0042594]	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	'de novo' AMP biosynthetic process [GO:0044208]; AMP biosynthetic process [GO:0006167]; aspartate metabolic process [GO:0006531]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; glutamine metabolic process [GO:0006541]; IMP metabolic process [GO:0046040]; purine nucleotide metabolic process [GO:0006163]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to muscle activity [GO:0014850]; response to starvation [GO:0042594]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytosol [GO:0005829]	actin filament binding [GO:0051015]; adenylosuccinate synthase activity [GO:0004019]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]
d1mf0a__d2afif___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; actin filament binding [GO:0051015]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; 'de novo' AMP biosynthetic process [GO:0044208]; AMP biosynthetic process [GO:0006167]; aspartate metabolic process [GO:0006531]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; glutamine metabolic process [GO:0006541]; IMP metabolic process [GO:0046040]; purine nucleotide metabolic process [GO:0006163]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to muscle activity [GO:0014850]; response to starvation [GO:0042594]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	'de novo' AMP biosynthetic process [GO:0044208]; AMP biosynthetic process [GO:0006167]; aspartate metabolic process [GO:0006531]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; glutamine metabolic process [GO:0006541]; IMP metabolic process [GO:0046040]; purine nucleotide metabolic process [GO:0006163]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to muscle activity [GO:0014850]; response to starvation [GO:0042594]	nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; membrane [GO:0016020]	molybdenum-iron nitrogenase complex [GO:0016612]	actin filament binding [GO:0051015]; adenylosuccinate synthase activity [GO:0004019]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1mf0a__d3msxa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; actin filament binding [GO:0051015]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; 'de novo' AMP biosynthetic process [GO:0044208]; AMP biosynthetic process [GO:0006167]; aspartate metabolic process [GO:0006531]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; glutamine metabolic process [GO:0006541]; IMP metabolic process [GO:0046040]; purine nucleotide metabolic process [GO:0006163]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to muscle activity [GO:0014850]; response to starvation [GO:0042594]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	'de novo' AMP biosynthetic process [GO:0044208]; AMP biosynthetic process [GO:0006167]; aspartate metabolic process [GO:0006531]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; glutamine metabolic process [GO:0006541]; IMP metabolic process [GO:0046040]; purine nucleotide metabolic process [GO:0006163]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to muscle activity [GO:0014850]; response to starvation [GO:0042594]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; membrane [GO:0016020]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	actin filament binding [GO:0051015]; adenylosuccinate synthase activity [GO:0004019]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d1mf2h1_d4hjjl2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d1mf2l1_d5wkid2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1mf2l2_d3esvf1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1mf2m1_d1wbzd___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1mf2m2_d2ojzm1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	metal ion binding [GO:0046872]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d1mf2n1_d3eyvh2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1mf8b__d1wlza1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	nucleoplasm [GO:0005654]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	calcium ion binding [GO:0005509]
d1mfah1_d1qrne2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1mfbl1_d3q3ga1__1		Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]
d1mfbl2_d3d2uh1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1mfcl1_d2xnab2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1mfdh1_d5x8lo1__1		Metazoa		Chordata		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		
d1mfdl2_d5bw7c2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		IgG binding [GO:0019864]
d1mfel2_d4jo4l1__1												
d1mffb__d4grob___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; brain renin-angiotensin system [GO:0002035]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; drinking behavior [GO:0042756]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of axon regeneration [GO:0048680]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of glycolytic process [GO:0045821]; positive regulation of immune response [GO:0050778]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of cell population proliferation [GO:0042127]; spermatogenesis [GO:0007283]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	brain renin-angiotensin system [GO:0002035]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; drinking behavior [GO:0042756]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of axon regeneration [GO:0048680]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of glycolytic process [GO:0045821]; positive regulation of immune response [GO:0050778]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of cell population proliferation [GO:0042127]; spermatogenesis [GO:0007283]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d1mfha__d3feka___1		Metazoa		Chordata		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1mfia__d2aagb2__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; brain renin-angiotensin system [GO:0002035]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; drinking behavior [GO:0042756]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of axon regeneration [GO:0048680]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of glycolytic process [GO:0045821]; positive regulation of immune response [GO:0050778]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of cell population proliferation [GO:0042127]; spermatogenesis [GO:0007283]		brain renin-angiotensin system [GO:0002035]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; drinking behavior [GO:0042756]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of axon regeneration [GO:0048680]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of glycolytic process [GO:0045821]; positive regulation of immune response [GO:0050778]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of cell population proliferation [GO:0042127]; spermatogenesis [GO:0007283]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]	
d1mfic__d3mlcc___1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; brain renin-angiotensin system [GO:0002035]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; drinking behavior [GO:0042756]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of axon regeneration [GO:0048680]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of glycolytic process [GO:0045821]; positive regulation of immune response [GO:0050778]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of cell population proliferation [GO:0042127]; spermatogenesis [GO:0007283]		brain renin-angiotensin system [GO:0002035]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; drinking behavior [GO:0042756]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of axon regeneration [GO:0048680]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of glycolytic process [GO:0045821]; positive regulation of immune response [GO:0050778]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of cell population proliferation [GO:0042127]; spermatogenesis [GO:0007283]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]	
d1mfrc__d3kx9w___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]
d1mfrf__d3ak8k___1	Metazoa		Chordata		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	
d1mfrg__d2x170___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d1mfri__d2jd83___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d1mfro__d2fl0e___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1mfro__d5i4jd___1	Metazoa		Chordata	Cyanobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1mfrq__d3a68j___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1mfrt__d1pj1a___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1mfrv__d3uofb___1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1mfrw__d3a9qa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1mfrx__d4cmyw___1	Metazoa		Chordata	Chlorobi	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d1mfva2_d1tmqa2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]	carbohydrate metabolic process [GO:0005975]		extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]
d1mg0a2_d4kqxa1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytosol [GO:0005829]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]
d1mg0d2_d4okia1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; polyketide synthase complex [GO:0034081]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; oxidoreductase activity [GO:0016491]; phosphopantetheine binding [GO:0031177]; Actinobacterium-type cell wall biogenesis [GO:0071766]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; phenolic phthiocerol biosynthetic process [GO:0097041]; phthiocerol biosynthetic process [GO:0097040]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	Actinobacterium-type cell wall biogenesis [GO:0071766]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; phenolic phthiocerol biosynthetic process [GO:0097041]; phthiocerol biosynthetic process [GO:0097040]	cytosol [GO:0005829]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; polyketide synthase complex [GO:0034081]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; oxidoreductase activity [GO:0016491]; phosphopantetheine binding [GO:0031177]
d1mg1a1_d4lz5b___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1mg2a__d3l4mf___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1mg2d__d4ye1a___1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	periplasmic space [GO:0042597]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1mg2g__d2jl0c1__1			Proteobacteria		periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	
d1mg2i__d2j57i___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1mg2l__d1bl9a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1mg2p__d1l9jc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1mg3c__d2w8cb___1			Proteobacteria	Cyanobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	thylakoid membrane [GO:0042651]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1mg3g__d3fswd___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1mg3k__d1rcya___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1mg3l__d1hj4a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1mg3m__d3rlmf___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	outer membrane-bounded periplasmic space [GO:0030288]; amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]; amine metabolic process [GO:0009308]		amine metabolic process [GO:0009308]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]
d1mg5b__d1b8pa1__1	Metazoa		Arthropoda	Proteobacteria	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; acetaldehyde metabolic process [GO:0006117]; alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; behavioral response to ethanol [GO:0048149]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; oxidation-reduction process [GO:0055114]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	acetaldehyde metabolic process [GO:0006117]; alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; behavioral response to ethanol [GO:0048149]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; oxidation-reduction process [GO:0055114]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]		acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]	L-malate dehydrogenase activity [GO:0030060]
d1mgqd__d4f7ue___1		Metazoa	Euryarchaeota	Chordata	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; RNA binding [GO:0003723]; U1 snRNP binding [GO:1990446]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]	mRNA splicing, via spliceosome [GO:0000398]	import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]	small nucleolar ribonucleoprotein complex [GO:0005732]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]		RNA binding [GO:0003723]; U1 snRNP binding [GO:1990446]
d1mgqg__d1n9si___1		Fungi	Euryarchaeota	Ascomycota	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	mRNA splicing, via spliceosome [GO:0000398]	mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	small nucleolar ribonucleoprotein complex [GO:0005732]	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]
d1mgra__d4bu4a___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1mh1a__d1jaha___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; histone deacetylase binding [GO:0042826]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cell-matrix adhesion [GO:0007160]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; histone deacetylase binding [GO:0042826]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1mh3a2_d4kfqb___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic branch [GO:0044307]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; synaptic membrane [GO:0097060]; terminal bouton [GO:0043195]; amyloid-beta binding [GO:0001540]; enzyme binding [GO:0019899]; glutamate binding [GO:0016595]; glutamate receptor binding [GO:0035254]; glycine binding [GO:0016594]; ionotropic glutamate receptor activity [GO:0004970]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; phosphatase binding [GO:0019902]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; cellular response to manganese ion [GO:0071287]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning or memory [GO:0007611]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of Schwann cell migration [GO:1900149]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to calcium ion [GO:0051592]; response to fungicide [GO:0060992]; response to organic cyclic compound [GO:0014070]; rhythmic process [GO:0048511]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cellular response to manganese ion [GO:0071287]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning or memory [GO:0007611]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of Schwann cell migration [GO:1900149]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to calcium ion [GO:0051592]; response to fungicide [GO:0060992]; response to organic cyclic compound [GO:0014070]; rhythmic process [GO:0048511]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic branch [GO:0044307]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; synaptic membrane [GO:0097060]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	amyloid-beta binding [GO:0001540]; enzyme binding [GO:0019899]; glutamate binding [GO:0016595]; glutamate receptor binding [GO:0035254]; glycine binding [GO:0016594]; ionotropic glutamate receptor activity [GO:0004970]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; signaling receptor binding [GO:0005102]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d1mh3a2_d5ot8a___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	nitrogen compound transport [GO:0071705]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	ligand-gated ion channel activity [GO:0015276]
d1mh5h1_d1h3wm1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1mh5l1_d3cxhu___1	Metazoa	Fungi	Chordata	Ascomycota	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1mhca2_d2wbja1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d1mhcb__d3miqe___1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1mhcd1_d1olla2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; SWI/SNF complex [GO:0016514]; cellular defense response [GO:0006968]; natural killer cell activation [GO:0030101]; regulation of immune response [GO:0050776]; regulation of natural killer cell mediated cytotoxicity [GO:0042269]; signal transduction [GO:0007165]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cellular defense response [GO:0006968]; natural killer cell activation [GO:0030101]; regulation of immune response [GO:0050776]; regulation of natural killer cell mediated cytotoxicity [GO:0042269]; signal transduction [GO:0007165]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; SWI/SNF complex [GO:0016514]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1mhce__d1jpsh1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]
d1mhce__d4l3cl___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1mhea1_d5o4ed1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1mhea2_d2clrd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1mheb__d5adol2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1mhec1_d4hwel1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1mhec2_d2icwe2__1	Metazoa		Chordata	Tenericutes	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1mhed__d4uujb1__1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	voltage-gated potassium channel complex [GO:0008076]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1mhha1_d1y18e1__1												
d1mhha1_d5dr5l1__1												
d1mhha2_d1o7va___1		Metazoa		Chordata		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; signaling receptor activity [GO:0038023]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]		cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; signaling receptor activity [GO:0038023]
d1mhhc1_d2gk0l1__1		Metazoa		Chordata								
d1mhhc1_d3kppa2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1mhpb__d1ck4a___1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]	collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]
d1mhpb__d3ppxa1__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d1mhph1_d1kt2c1__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]	
d1mhpx__d3bzea1__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1mhyd__d1kgpd___1			Proteobacteria	Actinobacteria	methane monooxygenase activity [GO:0015049]; methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		ribonucleoside-diphosphate reductase complex [GO:0005971]	methane monooxygenase activity [GO:0015049]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1mhyd__d1vlge___1			Proteobacteria	Thermotogae	methane monooxygenase activity [GO:0015049]; methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1mhzb__d1pj0a___1			Proteobacteria	Proteobacteria	methane monooxygenase activity [GO:0015049]; methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	methane monooxygenase activity [GO:0015049]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1mi4a__d3rmtc1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; 3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]	3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]
d1mi5a2_d1b0gd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1mi5a2_d2wbje1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d1mi5b__d2ykll1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1mi5e1_d4at6f1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1mi5e2_d2eh7l1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1mi5e2_d4lsul2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d1miel1_d1nqbc2__1												
d1miel2_d4lbea2__1				Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1mifc__d5hvta___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d1mihb__d2fspa___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	kinase activity [GO:0016301]; metal ion binding [GO:0046872]
d1mika__d3o7ta___1	Metazoa	Fungi	Chordata	Basidiomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1mila__d3vrna3__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; plasma membrane [GO:0005886]; Shc-EGFR complex [GO:0070435]; ephrin receptor binding [GO:0046875]; epidermal growth factor binding [GO:0048408]; epidermal growth factor receptor binding [GO:0005154]; insulin receptor binding [GO:0005158]; insulin-like growth factor receptor binding [GO:0005159]; neurotrophin TRKA receptor binding [GO:0005168]; phospholipid binding [GO:0005543]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; receptor tyrosine kinase binding [GO:0030971]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; actin cytoskeleton reorganization [GO:0031532]; activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell-cell adhesion [GO:0098609]; cellular response to growth factor stimulus [GO:0071363]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-2-mediated signaling pathway [GO:0038110]; IRE1-mediated unfolded protein response [GO:0036498]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of transcription, DNA-templated [GO:0045893]; Ras protein signal transduction [GO:0007265]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of growth [GO:0040008]; regulation of superoxide metabolic process [GO:0090322]; viral process [GO:0016032]	membrane raft [GO:0045121]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]; cell surface receptor signaling pathway [GO:0007166]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of MAP kinase activity [GO:0043407]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	actin cytoskeleton reorganization [GO:0031532]; activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell-cell adhesion [GO:0098609]; cellular response to growth factor stimulus [GO:0071363]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-2-mediated signaling pathway [GO:0038110]; IRE1-mediated unfolded protein response [GO:0036498]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of transcription, DNA-templated [GO:0045893]; Ras protein signal transduction [GO:0007265]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of growth [GO:0040008]; regulation of superoxide metabolic process [GO:0090322]; viral process [GO:0016032]	cell surface receptor signaling pathway [GO:0007166]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of MAP kinase activity [GO:0043407]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; plasma membrane [GO:0005886]; Shc-EGFR complex [GO:0070435]	membrane raft [GO:0045121]; plasma membrane [GO:0005886]	ephrin receptor binding [GO:0046875]; epidermal growth factor binding [GO:0048408]; epidermal growth factor receptor binding [GO:0005154]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; neurotrophin TRKA receptor binding [GO:0005168]; phospholipid binding [GO:0005543]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; receptor tyrosine kinase binding [GO:0030971]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]	calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]
d1miml1_d2iqal1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	metal ion binding [GO:0046872]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d1miml2_d3k3qa___1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	negative regulation of neurotransmitter secretion [GO:0046929]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1miob__d1m34j___1			Firmicutes	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1mioc__d3zk7b___1			Firmicutes	Firmicutes	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	nitrogen fixation [GO:0009399]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	molybdenum-iron nitrogenase complex [GO:0016612]	plasma membrane [GO:0005886]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	metal ion binding [GO:0046872]
d1miod__d3eiwa1__1			Firmicutes	Firmicutes	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	
d1miqa__d1w5wa___1			Apicomplexa		integral component of membrane [GO:0016021]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	integral component of membrane [GO:0016021]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1miua5_d1fgua2__1	Metazoa	Metazoa	Chordata	Chordata	BRCA2-MAGE-D1 complex [GO:0033593]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lateral element [GO:0000800]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; gamma-tubulin binding [GO:0043015]; H3 histone acetyltransferase activity [GO:0010484]; H4 histone acetyltransferase activity [GO:0010485]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; single-stranded DNA binding [GO:0003697]; brain development [GO:0007420]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; centrosome duplication [GO:0051298]; chordate embryonic development [GO:0043009]; chromosome organization [GO:0051276]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; establishment of protein localization to telomere [GO:0070200]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; homologous chromosome orientation involved in meiotic metaphase I plate congression [GO:0031619]; inner cell mass cell proliferation [GO:0001833]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; male meiosis I [GO:0007141]; mammary gland development [GO:0030879]; mitotic cytokinesis [GO:0000281]; mitotic recombination-dependent replication fork processing [GO:1990426]; multicellular organism growth [GO:0035264]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; nucleotide-excision repair [GO:0006289]; oocyte maturation [GO:0001556]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cytokinesis [GO:0032465]; replication fork protection [GO:0048478]; response to gamma radiation [GO:0010332]; response to UV-C [GO:0010225]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; telomere maintenance via recombination [GO:0000722]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]; damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	brain development [GO:0007420]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; centrosome duplication [GO:0051298]; chordate embryonic development [GO:0043009]; chromosome organization [GO:0051276]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; establishment of protein localization to telomere [GO:0070200]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; homologous chromosome orientation involved in meiotic metaphase I plate congression [GO:0031619]; inner cell mass cell proliferation [GO:0001833]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; male meiosis I [GO:0007141]; mammary gland development [GO:0030879]; mitotic cytokinesis [GO:0000281]; mitotic recombination-dependent replication fork processing [GO:1990426]; multicellular organism growth [GO:0035264]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; nucleotide-excision repair [GO:0006289]; oocyte maturation [GO:0001556]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cytokinesis [GO:0032465]; replication fork protection [GO:0048478]; response to gamma radiation [GO:0010332]; response to UV-C [GO:0010225]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; telomere maintenance via recombination [GO:0000722]	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	BRCA2-MAGE-D1 complex [GO:0033593]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lateral element [GO:0000800]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]	gamma-tubulin binding [GO:0043015]; H3 histone acetyltransferase activity [GO:0010484]; H4 histone acetyltransferase activity [GO:0010485]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; single-stranded DNA binding [GO:0003697]	damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]
d1miua5_d2n78a___1	Metazoa		Chordata	Proteobacteria	BRCA2-MAGE-D1 complex [GO:0033593]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lateral element [GO:0000800]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; gamma-tubulin binding [GO:0043015]; H3 histone acetyltransferase activity [GO:0010484]; H4 histone acetyltransferase activity [GO:0010485]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; single-stranded DNA binding [GO:0003697]; brain development [GO:0007420]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; centrosome duplication [GO:0051298]; chordate embryonic development [GO:0043009]; chromosome organization [GO:0051276]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; establishment of protein localization to telomere [GO:0070200]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; homologous chromosome orientation involved in meiotic metaphase I plate congression [GO:0031619]; inner cell mass cell proliferation [GO:0001833]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; male meiosis I [GO:0007141]; mammary gland development [GO:0030879]; mitotic cytokinesis [GO:0000281]; mitotic recombination-dependent replication fork processing [GO:1990426]; multicellular organism growth [GO:0035264]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; nucleotide-excision repair [GO:0006289]; oocyte maturation [GO:0001556]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cytokinesis [GO:0032465]; replication fork protection [GO:0048478]; response to gamma radiation [GO:0010332]; response to UV-C [GO:0010225]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; telomere maintenance via recombination [GO:0000722]	cytosol [GO:0005829]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation initiation factor activity [GO:0003743]	brain development [GO:0007420]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; centrosome duplication [GO:0051298]; chordate embryonic development [GO:0043009]; chromosome organization [GO:0051276]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; establishment of protein localization to telomere [GO:0070200]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; homologous chromosome orientation involved in meiotic metaphase I plate congression [GO:0031619]; inner cell mass cell proliferation [GO:0001833]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; male meiosis I [GO:0007141]; mammary gland development [GO:0030879]; mitotic cytokinesis [GO:0000281]; mitotic recombination-dependent replication fork processing [GO:1990426]; multicellular organism growth [GO:0035264]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; nucleotide-excision repair [GO:0006289]; oocyte maturation [GO:0001556]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cytokinesis [GO:0032465]; replication fork protection [GO:0048478]; response to gamma radiation [GO:0010332]; response to UV-C [GO:0010225]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; telomere maintenance via recombination [GO:0000722]		BRCA2-MAGE-D1 complex [GO:0033593]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lateral element [GO:0000800]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]	cytosol [GO:0005829]	gamma-tubulin binding [GO:0043015]; H3 histone acetyltransferase activity [GO:0010484]; H4 histone acetyltransferase activity [GO:0010485]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; single-stranded DNA binding [GO:0003697]	ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation initiation factor activity [GO:0003743]
d1mixa1_d3wa0b2__1	Metazoa	Metazoa	Chordata	Chordata	actin cortical patch [GO:0030479]; cell [GO:0005623]; cell surface [GO:0009986]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; clathrin light chain binding [GO:0032051]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; structural constituent of cytoskeleton [GO:0005200]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; clathrin coat assembly [GO:0048268]; cytoskeletal anchoring at plasma membrane [GO:0007016]; endocytosis [GO:0006897]; positive regulation of receptor-mediated endocytosis [GO:0048260]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; clathrin coat assembly [GO:0048268]; cytoskeletal anchoring at plasma membrane [GO:0007016]; endocytosis [GO:0006897]; positive regulation of receptor-mediated endocytosis [GO:0048260]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin cortical patch [GO:0030479]; cell [GO:0005623]; cell surface [GO:0009986]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	actin filament binding [GO:0051015]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; clathrin light chain binding [GO:0032051]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol binding [GO:0035091]; structural constituent of cytoskeleton [GO:0005200]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d1mj2c__d1mjmb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]	cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1mj7l1_d1figl2__1												
d1mj7l2_d2hvja2__1				Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1mj7l2_d4p5ma2__1		Metazoa		Chordata		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d1mj8l1_d1iisb4__1												
d1mjja1_d1l7tl1__1		Metazoa		Chordata								
d1mjjb1_d3i02c1__1												
d1mjjh1_d3qxvd___1												
d1mjjl1_d3ebaa1__1		Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]		antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1mjjl2_d5x8lm1__1		Metazoa		Chordata		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		
d1mjma__d1mjqi___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	methionine biosynthetic process [GO:0009086]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]	cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1mjna__d3zqkc___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d1mjul1_d2dqgh1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1mjxa__d3fq3a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1mjya__d3r5vd___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; membrane [GO:0016020]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1mk2a__d5jeka___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heteromeric SMAD protein complex [GO:0071144]; nuclear chromatin [GO:0000790]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]; beta-catenin binding [GO:0008013]; bHLH transcription factor binding [GO:0043425]; chromatin DNA binding [GO:0031490]; co-SMAD binding [GO:0070410]; collagen binding [GO:0005518]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; glucocorticoid receptor binding [GO:0035259]; identical protein binding [GO:0042802]; mineralocorticoid receptor binding [GO:0031962]; phosphatase binding [GO:0019902]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; proximal promoter sequence-specific DNA binding [GO:0000987]; R-SMAD binding [GO:0070412]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transforming growth factor beta receptor binding [GO:0005160]; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [GO:0030618]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activin receptor signaling pathway [GO:0032924]; adrenal gland development [GO:0030325]; cell cycle arrest [GO:0007050]; cell-cell junction organization [GO:0045216]; cellular response to cytokine stimulus [GO:0071345]; cellular response to transforming growth factor beta stimulus [GO:0071560]; developmental growth [GO:0048589]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic foregut morphogenesis [GO:0048617]; embryonic pattern specification [GO:0009880]; endoderm development [GO:0007492]; evasion or tolerance of host defenses by virus [GO:0019049]; extrinsic apoptotic signaling pathway [GO:0097191]; heart looping [GO:0001947]; immune response [GO:0006955]; immune system development [GO:0002520]; in utero embryonic development [GO:0001701]; lens fiber cell differentiation [GO:0070306]; liver development [GO:0001889]; mesoderm formation [GO:0001707]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of cell growth [GO:0030308]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of inflammatory response [GO:0050728]; negative regulation of lung blood pressure [GO:0061767]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; nodal signaling pathway [GO:0038092]; osteoblast development [GO:0002076]; paraxial mesoderm morphogenesis [GO:0048340]; pericardium development [GO:0060039]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of bone mineralization [GO:0030501]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta3 production [GO:0032916]; primary miRNA processing [GO:0031053]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of binding [GO:0051098]; regulation of epithelial cell proliferation [GO:0050678]; regulation of immune response [GO:0050776]; regulation of striated muscle tissue development [GO:0016202]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; signal transduction involved in regulation of gene expression [GO:0023019]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somitogenesis [GO:0001756]; T cell activation [GO:0042110]; thyroid gland development [GO:0030878]; transdifferentiation [GO:0060290]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activin receptor signaling pathway [GO:0032924]; adrenal gland development [GO:0030325]; cell-cell junction organization [GO:0045216]; cell cycle arrest [GO:0007050]; cellular response to cytokine stimulus [GO:0071345]; cellular response to transforming growth factor beta stimulus [GO:0071560]; developmental growth [GO:0048589]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic foregut morphogenesis [GO:0048617]; embryonic pattern specification [GO:0009880]; endoderm development [GO:0007492]; evasion or tolerance of host defenses by virus [GO:0019049]; extrinsic apoptotic signaling pathway [GO:0097191]; heart looping [GO:0001947]; immune response [GO:0006955]; immune system development [GO:0002520]; in utero embryonic development [GO:0001701]; lens fiber cell differentiation [GO:0070306]; liver development [GO:0001889]; mesoderm formation [GO:0001707]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of cell growth [GO:0030308]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of inflammatory response [GO:0050728]; negative regulation of lung blood pressure [GO:0061767]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; nodal signaling pathway [GO:0038092]; osteoblast development [GO:0002076]; paraxial mesoderm morphogenesis [GO:0048340]; pericardium development [GO:0060039]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of bone mineralization [GO:0030501]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta3 production [GO:0032916]; primary miRNA processing [GO:0031053]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of binding [GO:0051098]; regulation of epithelial cell proliferation [GO:0050678]; regulation of immune response [GO:0050776]; regulation of striated muscle tissue development [GO:0016202]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta2 production [GO:0032909]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to hypoxia [GO:0001666]; signal transduction involved in regulation of gene expression [GO:0023019]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somitogenesis [GO:0001756]; T cell activation [GO:0042110]; thyroid gland development [GO:0030878]; transdifferentiation [GO:0060290]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heteromeric SMAD protein complex [GO:0071144]; nuclear chromatin [GO:0000790]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	beta-catenin binding [GO:0008013]; bHLH transcription factor binding [GO:0043425]; chromatin DNA binding [GO:0031490]; collagen binding [GO:0005518]; co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; glucocorticoid receptor binding [GO:0035259]; identical protein binding [GO:0042802]; mineralocorticoid receptor binding [GO:0031962]; phosphatase binding [GO:0019902]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; R-SMAD binding [GO:0070412]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [GO:0030618]; transforming growth factor beta receptor binding [GO:0005160]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]
d1mk4b1_d1yk3c___1			Firmicutes	Actinobacteria	N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acyl-CoA hydrolase activity [GO:0047617]; N-acyltransferase activity [GO:0016410]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; siderophore biosynthetic process from catechol [GO:0019540]		siderophore biosynthetic process from catechol [GO:0019540]			N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acyl-CoA hydrolase activity [GO:0047617]; N-acyltransferase activity [GO:0016410]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1mk7d1_d3wa0a2__1	Metazoa	Metazoa	Chordata	Chordata	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d1mk8a__d5ccpa___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1mk9b1_d2aeha1__1	Metazoa	Metazoa	Chordata	Chordata	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]; actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]	ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]
d1mk9b1_d4zrkc2__1	Metazoa	Metazoa	Chordata	Chordata	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d1mk9f1_d1gc7a1__1	Metazoa	Metazoa	Chordata	Chordata	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d1mk9f2_d1ni2b2__1	Metazoa	Metazoa	Chordata	Chordata	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]
d1mk9f2_d2k2ua___1	Metazoa	Fungi	Chordata	Ascomycota	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]; nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]	phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]
d1mkaa__d2glpd___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d1mkab__d3azas___1			Proteobacteria	Apicomplexa	cytosol [GO:0005829]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]	hydro-lyase activity [GO:0016836]
d1mkdd__d5b4ka___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d1mkde__d3ly2e___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d1mkde__d5tzwc___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d1mkdf__d2gz4c___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]		adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]		apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]		3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	
d1mkdh__d1ro9b___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d1mkdh__d4phwb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d1mkod__d1liak___1	Metazoa		Chordata	Rhodophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1mkpa__d5bzzb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; activation of MAPK activity [GO:0000187]; cell differentiation [GO:0030154]; inactivation of MAPK activity [GO:0000188]; MAPK cascade [GO:0000165]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of apoptotic process [GO:0043065]; protein dephosphorylation [GO:0006470]; regulation of heart growth [GO:0060420]; response to drug [GO:0042493]; response to growth factor [GO:0070848]; response to nitrosative stress [GO:0051409]; response to organic cyclic compound [GO:0014070]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; ubiquitin-specific protease binding [GO:1990381]; adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	activation of MAPK activity [GO:0000187]; cell differentiation [GO:0030154]; inactivation of MAPK activity [GO:0000188]; MAPK cascade [GO:0000165]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of apoptotic process [GO:0043065]; protein dephosphorylation [GO:0006470]; regulation of heart growth [GO:0060420]; response to drug [GO:0042493]; response to growth factor [GO:0070848]; response to nitrosative stress [GO:0051409]; response to organic cyclic compound [GO:0014070]	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381]
d1mkpa__d5ka1a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; activation of MAPK activity [GO:0000187]; cell differentiation [GO:0030154]; inactivation of MAPK activity [GO:0000188]; MAPK cascade [GO:0000165]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of apoptotic process [GO:0043065]; protein dephosphorylation [GO:0006470]; regulation of heart growth [GO:0060420]; response to drug [GO:0042493]; response to growth factor [GO:0070848]; response to nitrosative stress [GO:0051409]; response to organic cyclic compound [GO:0014070]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	activation of MAPK activity [GO:0000187]; cell differentiation [GO:0030154]; inactivation of MAPK activity [GO:0000188]; MAPK cascade [GO:0000165]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of apoptotic process [GO:0043065]; protein dephosphorylation [GO:0006470]; regulation of heart growth [GO:0060420]; response to drug [GO:0042493]; response to growth factor [GO:0070848]; response to nitrosative stress [GO:0051409]; response to organic cyclic compound [GO:0014070]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1mkwk__d2xc5a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1mkx.1_d1z7ka___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1ml1e__d4nvtb___1				Proteobacteria	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytoplasm [GO:0005737]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1ml1i__d1tcda___1					cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1ml1i__d4wjea___1					cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytosol [GO:0005829]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1ml3a2_d1drua2__1				Proteobacteria	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; cellular amino acid biosynthetic process [GO:0008652]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cellular amino acid biosynthetic process [GO:0008652]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycosome [GO:0020015]	cytosol [GO:0005829]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]
d1ml3b2_d1nqoc2__1				Firmicutes	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glycosome [GO:0020015]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1ml3b2_d1t1sb4__1				Proteobacteria	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	glycosome [GO:0020015]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]
d1ml4a1_d2fzka2__1			Euryarchaeota	Proteobacteria	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1ml7a__d2f73h2__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	vasodilation [GO:0042311]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]
d1mlba1_d1qz1a2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]
d1mlcc1_d1ce1h1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1mlcc2_d1x9qa2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1mlcd1_d4jo3l1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	structural molecule activity [GO:0005198]
d1mlce__d135la___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1mlcf__d4cgee___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	hydrolase activity [GO:0016787]
d1mldc1_d5nqbb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; chaperone binding [GO:0051087]; L-malate dehydrogenase activity [GO:0030060]; protein homodimerization activity [GO:0042803]; aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	chaperone binding [GO:0051087]; L-malate dehydrogenase activity [GO:0030060]; protein homodimerization activity [GO:0042803]	L-lactate dehydrogenase activity [GO:0004459]
d1mldd1_d1rwba___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; chaperone binding [GO:0051087]; L-malate dehydrogenase activity [GO:0030060]; protein homodimerization activity [GO:0042803]; aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; sporulation resulting in formation of a cellular spore [GO:0030435]	aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	sporulation resulting in formation of a cellular spore [GO:0030435]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		chaperone binding [GO:0051087]; L-malate dehydrogenase activity [GO:0030060]; protein homodimerization activity [GO:0042803]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]
d1mlfa__d1mbsa___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1mlga__d4i0va___1	Metazoa		Chordata		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1mlha__d4z8ka___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1mlja__d1clsb___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1mlla__d1n9fa___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1mlma__d2in4a___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1mlqa__d2qrwh___1	Metazoa		Chordata	Actinobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1mlra__d2vlza___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1mlyb__d5g0ad___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	biotin biosynthetic process [GO:0009102]		cytoplasm [GO:0005737]		adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1mlyb__d5vwob___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	biotin biosynthetic process [GO:0009102]	arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]	ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]
d1mlzb__d2fnua___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; polysaccharide biosynthetic process [GO:0000271]	biotin biosynthetic process [GO:0009102]	polysaccharide biosynthetic process [GO:0000271]	cytoplasm [GO:0005737]		adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1mm6a1_d1rkma___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	protein transport [GO:0015031]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	peptide transmembrane transporter activity [GO:1904680]
d1mm7b__d1fqfa___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d1mmba__d1d5ja___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1mmba__d3scjb___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1mmfl__d5reqa1__1			Proteobacteria	Actinobacteria	cobalamin binding [GO:0031419]; glycerol dehydratase activity [GO:0046405]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]					cobalamin binding [GO:0031419]; glycerol dehydratase activity [GO:0046405]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d1mmib2_d5tupc1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	integral component of membrane [GO:0016021]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; myosin binding [GO:0017022]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	integral component of membrane [GO:0016021]; nucleus [GO:0005634]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; myosin binding [GO:0017022]
d1mmib3_d4tr8b2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1mmjn__d2zu5a___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1mmka__d4v06b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; iron ion binding [GO:0005506]; phenylalanine 4-monooxygenase activity [GO:0004505]; catecholamine biosynthetic process [GO:0042423]; cellular amino acid biosynthetic process [GO:0008652]; L-phenylalanine catabolic process [GO:0006559]; neurotransmitter biosynthetic process [GO:0042136]; tyrosine biosynthetic process [GO:0006571]	cytosol [GO:0005829]; neuron projection [GO:0043005]; iron ion binding [GO:0005506]; tryptophan 5-monooxygenase activity [GO:0004510]; aromatic amino acid family metabolic process [GO:0009072]; cellular response to lithium ion [GO:0071285]; circadian rhythm [GO:0007623]; indolalkylamine biosynthetic process [GO:0046219]; response to activity [GO:0014823]; response to calcium ion [GO:0051592]; response to estrogen [GO:0043627]; response to glucocorticoid [GO:0051384]; response to nutrient levels [GO:0031667]; serotonin biosynthetic process [GO:0042427]	catecholamine biosynthetic process [GO:0042423]; cellular amino acid biosynthetic process [GO:0008652]; L-phenylalanine catabolic process [GO:0006559]; neurotransmitter biosynthetic process [GO:0042136]; tyrosine biosynthetic process [GO:0006571]	aromatic amino acid family metabolic process [GO:0009072]; cellular response to lithium ion [GO:0071285]; circadian rhythm [GO:0007623]; indolalkylamine biosynthetic process [GO:0046219]; response to activity [GO:0014823]; response to calcium ion [GO:0051592]; response to estrogen [GO:0043627]; response to glucocorticoid [GO:0051384]; response to nutrient levels [GO:0031667]; serotonin biosynthetic process [GO:0042427]	cytosol [GO:0005829]	cytosol [GO:0005829]; neuron projection [GO:0043005]	iron ion binding [GO:0005506]; phenylalanine 4-monooxygenase activity [GO:0004505]	iron ion binding [GO:0005506]; tryptophan 5-monooxygenase activity [GO:0004510]
d1mmob__d2bq1i1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	ribonucleoside-diphosphate reductase complex [GO:0005971]; ATP binding [GO:0005524]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ATP binding [GO:0005524]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1mmod__d2htnc___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1mmqa__d3qh1a___1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1mmra__d1slma2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1mmsa2_d3cjrb2__1			Thermotogae	Deinococcus-Thermus	cytosolic large ribosomal subunit [GO:0022625]; large ribosomal subunit [GO:0015934]; large ribosomal subunit rRNA binding [GO:0070180]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	cytoplasm [GO:0005737]; protein methyltransferase activity [GO:0008276]	ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]; large ribosomal subunit [GO:0015934]	cytoplasm [GO:0005737]	large ribosomal subunit rRNA binding [GO:0070180]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	protein methyltransferase activity [GO:0008276]
d1mmua1_d2f7ra2__1		Metazoa	Firmicutes	Arthropoda	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	galactose metabolic process [GO:0006012]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1mmya1_d3t2ob5__1			Firmicutes	Proteobacteria	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1mmyb1_d2f2hb2__1			Firmicutes	Proteobacteria	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	galactose metabolic process [GO:0006012]	carbohydrate metabolic process [GO:0005975]			aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1mmza1_d4ttgc5__1			Firmicutes	Proteobacteria	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1mn0a1_d3vdbb5__1			Firmicutes	Proteobacteria	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1mn1a__d1u2jf___1	Fungi		Basidiomycota	Proteobacteria	extracellular region [GO:0005576]; heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	cytosol [GO:0005829]	heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]
d1mn7b__d4s0mf___1				Proteobacteria	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1mn8a__d2h3ia___1					host cell late endosome membrane [GO:0044185]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral budding via host ESCRT complex [GO:0039702]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral budding via host ESCRT complex [GO:0039702]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell late endosome membrane [GO:0044185]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1mn8c__d2h3qa___1					host cell late endosome membrane [GO:0044185]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral budding via host ESCRT complex [GO:0039702]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral budding via host ESCRT complex [GO:0039702]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell late endosome membrane [GO:0044185]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1mn9a__d3g2xa___1					cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1mn9a__d3prvd___1					cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d1mn9b__d3prvb___1					cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d1mnfe2_d1oelg2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]
d1mnga2_d2bkbc2__1			Deinococcus-Thermus	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]
d1mngb1_d1bs3b1__1			Deinococcus-Thermus	Actinobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1mngb2_d1gn3b2__1			Deinococcus-Thermus	Actinobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1mnkb__d3pi1b___1	Metazoa	Metazoa	Chordata	Mollusca	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1mnla__d4mon.4__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta								
d1mnma__d3mu6a___1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; DNA replication origin binding [GO:0003688]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein dimerization activity [GO:0046983]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II proximal promoter sequence-specific DNA binding, bending [GO:0044377]; RNA polymerase II repressing transcription factor binding [GO:0001103]; sequence-specific DNA binding [GO:0043565]; arginine metabolic process [GO:0006525]; negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:1900465]; negative regulation of mating-type specific transcription from RNA polymerase II promoter [GO:0001198]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter [GO:1900466]; positive regulation of mating-type specific transcription from RNA polymerase II promoter [GO:0001197]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription involved in G2/M transition of mitotic cell cycle [GO:0090282]; regulation of mating type switching [GO:0031494]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	arginine metabolic process [GO:0006525]; negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:1900465]; negative regulation of mating-type specific transcription from RNA polymerase II promoter [GO:0001198]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter [GO:1900466]; positive regulation of mating-type specific transcription from RNA polymerase II promoter [GO:0001197]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription involved in G2/M transition of mitotic cell cycle [GO:0090282]; regulation of mating type switching [GO:0031494]	apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; DNA replication origin binding [GO:0003688]; protein dimerization activity [GO:0046983]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II proximal promoter sequence-specific DNA binding, bending [GO:0044377]; RNA polymerase II repressing transcription factor binding [GO:0001103]; sequence-specific DNA binding [GO:0043565]	activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1mnmb__d1hbxd___1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; DNA replication origin binding [GO:0003688]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein dimerization activity [GO:0046983]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II proximal promoter sequence-specific DNA binding, bending [GO:0044377]; RNA polymerase II repressing transcription factor binding [GO:0001103]; sequence-specific DNA binding [GO:0043565]; arginine metabolic process [GO:0006525]; negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:1900465]; negative regulation of mating-type specific transcription from RNA polymerase II promoter [GO:0001198]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter [GO:1900466]; positive regulation of mating-type specific transcription from RNA polymerase II promoter [GO:0001197]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription involved in G2/M transition of mitotic cell cycle [GO:0090282]; regulation of mating type switching [GO:0031494]	cell [GO:0005623]; cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone deacetylase binding [GO:0042826]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; serum response element binding [GO:0010736]; transcription factor binding [GO:0008134]; actin cytoskeleton organization [GO:0030036]; angiogenesis involved in wound healing [GO:0060055]; associative learning [GO:0008306]; bicellular tight junction assembly [GO:0070830]; branching involved in blood vessel morphogenesis [GO:0001569]; bronchus cartilage development [GO:0060532]; cardiac myofibril assembly [GO:0055003]; cardiac vascular smooth muscle cell differentiation [GO:0060947]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-matrix adhesion [GO:0007160]; cellular response to glucose stimulus [GO:0071333]; cellular senescence [GO:0090398]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; epithelial cell-cell adhesion [GO:0090136]; epithelial structure maintenance [GO:0010669]; erythrocyte development [GO:0048821]; eyelid development in camera-type eye [GO:0061029]; face development [GO:0060324]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula formation [GO:0060347]; hematopoietic stem cell differentiation [GO:0060218]; hippocampus development [GO:0021766]; long-term memory [GO:0007616]; long-term synaptic depression [GO:0060292]; lung morphogenesis [GO:0060425]; lung smooth muscle development [GO:0061145]; megakaryocyte development [GO:0035855]; mesoderm formation [GO:0001707]; morphogenesis of an epithelial sheet [GO:0002011]; mRNA transcription by RNA polymerase II [GO:0042789]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; neuron development [GO:0048666]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; positive regulation of axon extension [GO:0045773]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of transcription by glucose [GO:0046016]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003257]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of transcription via serum response element binding [GO:0010735]; positive thymic T cell selection [GO:0045059]; primitive streak formation [GO:0090009]; regulation of cell adhesion [GO:0030155]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of water loss via skin [GO:0033561]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to toxic substance [GO:0009636]; sarcomere organization [GO:0045214]; skin morphogenesis [GO:0043589]; stress fiber assembly [GO:0043149]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea cartilage development [GO:0060534]; transcription by RNA polymerase II [GO:0006366]; trophectodermal cell differentiation [GO:0001829]	arginine metabolic process [GO:0006525]; negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:1900465]; negative regulation of mating-type specific transcription from RNA polymerase II promoter [GO:0001198]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter [GO:1900466]; positive regulation of mating-type specific transcription from RNA polymerase II promoter [GO:0001197]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription involved in G2/M transition of mitotic cell cycle [GO:0090282]; regulation of mating type switching [GO:0031494]	actin cytoskeleton organization [GO:0030036]; angiogenesis involved in wound healing [GO:0060055]; associative learning [GO:0008306]; bicellular tight junction assembly [GO:0070830]; branching involved in blood vessel morphogenesis [GO:0001569]; bronchus cartilage development [GO:0060532]; cardiac myofibril assembly [GO:0055003]; cardiac vascular smooth muscle cell differentiation [GO:0060947]; cell-matrix adhesion [GO:0007160]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to glucose stimulus [GO:0071333]; cellular senescence [GO:0090398]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; epithelial cell-cell adhesion [GO:0090136]; epithelial structure maintenance [GO:0010669]; erythrocyte development [GO:0048821]; eyelid development in camera-type eye [GO:0061029]; face development [GO:0060324]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula formation [GO:0060347]; hematopoietic stem cell differentiation [GO:0060218]; hippocampus development [GO:0021766]; long-term memory [GO:0007616]; long-term synaptic depression [GO:0060292]; lung morphogenesis [GO:0060425]; lung smooth muscle development [GO:0061145]; megakaryocyte development [GO:0035855]; mesoderm formation [GO:0001707]; morphogenesis of an epithelial sheet [GO:0002011]; mRNA transcription by RNA polymerase II [GO:0042789]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; neuron development [GO:0048666]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; positive regulation of axon extension [GO:0045773]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of transcription by glucose [GO:0046016]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003257]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of transcription via serum response element binding [GO:0010735]; positive thymic T cell selection [GO:0045059]; primitive streak formation [GO:0090009]; regulation of cell adhesion [GO:0030155]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of water loss via skin [GO:0033561]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to toxic substance [GO:0009636]; sarcomere organization [GO:0045214]; skin morphogenesis [GO:0043589]; stress fiber assembly [GO:0043149]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea cartilage development [GO:0060534]; transcription by RNA polymerase II [GO:0006366]; trophectodermal cell differentiation [GO:0001829]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; DNA replication origin binding [GO:0003688]; protein dimerization activity [GO:0046983]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II proximal promoter sequence-specific DNA binding, bending [GO:0044377]; RNA polymerase II repressing transcription factor binding [GO:0001103]; sequence-specific DNA binding [GO:0043565]	chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone deacetylase binding [GO:0042826]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; serum response element binding [GO:0010736]; transcription factor binding [GO:0008134]
d1mnoa__d2zssa___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1mnpa__d1fe2a1__1	Fungi	Metazoa	Basidiomycota	Chordata	extracellular region [GO:0005576]; heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1mnsa2_d3qkfd1__1			Proteobacteria		mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]		cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]				mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]	
d1mnuh1_d5i1cl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1mnuh2_d1tvhe2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1mnul1_d3o8xb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1mnya__d1ldca2__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; response to cadmium ion [GO:0046686]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	response to cadmium ion [GO:0046686]	lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]
d1mo8a__d2agvb4__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; caveola [GO:0005901]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; intercalated disc [GO:0014704]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; sarcolemma [GO:0042383]; sodium:potassium-exchanging ATPase complex [GO:0005890]; T-tubule [GO:0030315]; ADP binding [GO:0043531]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; phosphatase activity [GO:0016791]; phosphatidylinositol 3-kinase binding [GO:0043548]; potassium ion binding [GO:0030955]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; sodium ion binding [GO:0031402]; sodium:potassium-exchanging ATPase activity [GO:0005391]; steroid hormone binding [GO:1990239]; cardiac muscle contraction [GO:0060048]; cellular potassium ion homeostasis [GO:0030007]; cellular response to mechanical stimulus [GO:0071260]; cellular response to steroid hormone stimulus [GO:0071383]; cellular sodium ion homeostasis [GO:0006883]; energy coupled proton transmembrane transport, against electrochemical gradient [GO:0015988]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; membrane hyperpolarization [GO:0060081]; membrane repolarization [GO:0086009]; negative regulation of glucocorticoid biosynthetic process [GO:0031947]; negative regulation of heart contraction [GO:0045822]; positive regulation of heart contraction [GO:0045823]; positive regulation of striated muscle contraction [GO:0045989]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; regulation of blood pressure [GO:0008217]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of sodium ion transport [GO:0002028]; regulation of the force of heart contraction [GO:0002026]; relaxation of cardiac muscle [GO:0055119]; response to drug [GO:0042493]; response to glycoside [GO:1903416]; sodium ion export across plasma membrane [GO:0036376]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	cardiac muscle contraction [GO:0060048]; cellular potassium ion homeostasis [GO:0030007]; cellular response to mechanical stimulus [GO:0071260]; cellular response to steroid hormone stimulus [GO:0071383]; cellular sodium ion homeostasis [GO:0006883]; energy coupled proton transmembrane transport, against electrochemical gradient [GO:0015988]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; membrane hyperpolarization [GO:0060081]; membrane repolarization [GO:0086009]; negative regulation of glucocorticoid biosynthetic process [GO:0031947]; negative regulation of heart contraction [GO:0045822]; positive regulation of heart contraction [GO:0045823]; positive regulation of striated muscle contraction [GO:0045989]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; regulation of blood pressure [GO:0008217]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of sodium ion transport [GO:0002028]; regulation of the force of heart contraction [GO:0002026]; relaxation of cardiac muscle [GO:0055119]; response to drug [GO:0042493]; response to glycoside [GO:1903416]; sodium ion export across plasma membrane [GO:0036376]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085]	calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	apical plasma membrane [GO:0016324]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; caveola [GO:0005901]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; intercalated disc [GO:0014704]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; sarcolemma [GO:0042383]; sodium:potassium-exchanging ATPase complex [GO:0005890]; T-tubule [GO:0030315]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]	ADP binding [GO:0043531]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; phosphatase activity [GO:0016791]; phosphatidylinositol 3-kinase binding [GO:0043548]; potassium ion binding [GO:0030955]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; sodium:potassium-exchanging ATPase activity [GO:0005391]; sodium ion binding [GO:0031402]; steroid hormone binding [GO:1990239]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]
d1moda__d5e6eb___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1moea1_d3bn9c1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1moea2_d3u6rl___1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1moeb1_d4ei5b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1moeb2_d1j1oh___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1moha__d1yhuf___1	Metazoa	Metazoa	Mollusca	Annelida	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen transport [GO:0015671]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	oxygen transport [GO:0015671]		extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1mojd__d5jkll___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1mokc3_d1q1wb3__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; 2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]; (+)-camphor catabolic process [GO:0019383]	cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]	(+)-camphor catabolic process [GO:0019383]	cell [GO:0005623]		2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]
d1mokd3_d1dxlc3__1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; 2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]	cell [GO:0005623]; glycine cleavage complex [GO:0005960]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]; glycine cleavage complex [GO:0005960]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]	dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]
d1mola__d4n6ob1__1	Viridiplantae	Metazoa	Streptophyta	Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; perinuclear region of cytoplasm [GO:0048471]; cysteine-type endopeptidase activity [GO:0004197]; peptidase activity [GO:0008233]; tau protein binding [GO:0048156]; activation of cysteine-type endopeptidase activity [GO:0097202]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; associative learning [GO:0008306]; cellular response to amyloid-beta [GO:1904646]; cellular response to calcium ion [GO:0071277]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; dendritic spine organization [GO:0097061]; memory [GO:0007613]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of gene expression [GO:0010629]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; receptor catabolic process [GO:0032801]; renal system process [GO:0003014]; response to acidic pH [GO:0010447]; self proteolysis [GO:0097264]; toll-like receptor signaling pathway [GO:0002224]; vacuolar protein processing [GO:0006624]; vitamin D metabolic process [GO:0042359]		activation of cysteine-type endopeptidase activity [GO:0097202]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; associative learning [GO:0008306]; cellular response to amyloid-beta [GO:1904646]; cellular response to calcium ion [GO:0071277]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; dendritic spine organization [GO:0097061]; memory [GO:0007613]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of gene expression [GO:0010629]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; receptor catabolic process [GO:0032801]; renal system process [GO:0003014]; response to acidic pH [GO:0010447]; self proteolysis [GO:0097264]; toll-like receptor signaling pathway [GO:0002224]; vacuolar protein processing [GO:0006624]; vitamin D metabolic process [GO:0042359]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; perinuclear region of cytoplasm [GO:0048471]		cysteine-type endopeptidase activity [GO:0004197]; peptidase activity [GO:0008233]; tau protein binding [GO:0048156]
d1mora__d1tzba___1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]; carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]		carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]
d1mora__d2o2db___1			Proteobacteria		cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	glycosome [GO:0020015]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	glycosome [GO:0020015]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	glucose-6-phosphate isomerase activity [GO:0004347]
d1mosa__d3nbue___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytosol [GO:0005829]; glucose-6-phosphate isomerase activity [GO:0004347]; identical protein binding [GO:0042802]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; cellular response to oxidative stress [GO:0034599]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cellular response to oxidative stress [GO:0034599]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytosol [GO:0005829]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	glucose-6-phosphate isomerase activity [GO:0004347]; identical protein binding [GO:0042802]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d1moxa1_d1ozna___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; axonogenesis [GO:0007409]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	axonogenesis [GO:0007409]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative regulation of axon extension [GO:0030517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]
d1moxa2_d2xwtc___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]; activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]
d1mp0a2_d1n9gd2__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]	trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]
d1mp3a__d1g2vd___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	extracellular polysaccharide biosynthetic process [GO:0045226]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]			glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1mp4a__d1hjla___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]; bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]	extracellular polysaccharide biosynthetic process [GO:0045226]	bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]		cytoplasm [GO:0005737]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]
d1mp4a__d4b42c___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	extracellular polysaccharide biosynthetic process [GO:0045226]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]			glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1mp4b__d2y6pa___1			Proteobacteria	Aquificae	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	cytosol [GO:0005829]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	extracellular polysaccharide biosynthetic process [GO:0045226]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]		cytosol [GO:0005829]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]
d1mp5a__d3oama___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	cytosol [GO:0005829]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide core region biosynthetic process [GO:0009244]		cytosol [GO:0005829]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]
d1mp5a__d4ho9a___1			Proteobacteria	Firmicutes	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	extracellular polysaccharide biosynthetic process [GO:0045226]			glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1mp5b__d4ho5b___1			Proteobacteria	Firmicutes	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	extracellular polysaccharide biosynthetic process [GO:0045226]			glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1mp9a2_d1qn3b1__1		Viridiplantae	Crenarchaeota	Streptophyta	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]		nucleus [GO:0005634]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1mp9a2_d1vtoa2__1		Viridiplantae	Crenarchaeota	Streptophyta	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]		nucleus [GO:0005634]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1mpah1_d1ymha2__1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell wall [GO:0005618]; extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]
d1mpga1_d1yqma1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]
d1mpga2_d1c9bb1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1mpha__d4zrib3__1	Metazoa	Metazoa	Chordata	Chordata	axolemma [GO:0030673]; cortical cytoskeleton [GO:0030863]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin [GO:0008091]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; structural constituent of cytoskeleton [GO:0005200]; actin filament capping [GO:0051693]; common-partner SMAD protein phosphorylation [GO:0007182]; Golgi to plasma membrane protein transport [GO:0043001]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin filament capping [GO:0051693]; common-partner SMAD protein phosphorylation [GO:0007182]; Golgi to plasma membrane protein transport [GO:0043001]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390]	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	axolemma [GO:0030673]; cortical cytoskeleton [GO:0030863]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin [GO:0008091]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; structural constituent of cytoskeleton [GO:0005200]	actin binding [GO:0003779]
d1mppa__d3o9da___1	Fungi		Mucoromycota		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]
d1mpua__d1j35b___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; MHC class I protein binding [GO:0042288]; MHC class Ib receptor activity [GO:0032394]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; MHC class Ib receptor activity [GO:0032394]; MHC class I protein binding [GO:0042288]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]
d1mpua__d4n38d___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; MHC class I protein binding [GO:0042288]; MHC class Ib receptor activity [GO:0032394]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; MHC class Ib receptor activity [GO:0032394]; MHC class I protein binding [GO:0042288]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1mpyd1_d3hpvd1__1			Proteobacteria	Proteobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; toluene catabolic process [GO:0042203]	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	toluene catabolic process [GO:0042203]	aromatic compound catabolic process [GO:0019439]			catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]
d1mq1b__d4cfqd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell leading edge [GO:0031252]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin-dependent ATPase activity [GO:0030898]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]; actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell leading edge [GO:0031252]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; actin-dependent ATPase activity [GO:0030898]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]
d1mq5a__d1bbr.2__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]
d1mq8a2_d1waaa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1mqaa1_d3ppya1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d1mqdb__d2zzxd___1	Metazoa		Chordata	Deinococcus-Thermus	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; lactate transport [GO:0015727]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	lactate transport [GO:0015727]; transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]
d1mqga__d3iltb___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1mqga__d4rnsc___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; aromatic compound catabolic process [GO:0019439]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	aromatic compound catabolic process [GO:0019439]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1mqha__d4i9da___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]
d1mqja__d2fnca1__1	Metazoa		Chordata	Thermotogae	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	proteasome core complex, alpha-subunit complex [GO:0019773]; carbohydrate transmembrane transporter activity [GO:0015144]; endopeptidase activity [GO:0004175]; ubiquitin-dependent protein catabolic process [GO:0006511]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ubiquitin-dependent protein catabolic process [GO:0006511]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	proteasome core complex, alpha-subunit complex [GO:0019773]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbohydrate transmembrane transporter activity [GO:0015144]; endopeptidase activity [GO:0004175]
d1mqkh__d2xfxb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1mqla__d5kana___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1mqma__d4ln8k___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d1mqma__d4unze___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1mqmd__d4wssb1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1mqmg__d4wsxw___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1mqng__d4wsua1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1mqoa__d2ohhd1__1			Firmicutes	Euryarchaeota	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1mqqa1_d2wc4c___1			Firmicutes	Thermotogae	extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; xylan catabolic process [GO:0045493]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1mqra2_d2v5cb1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	glucuronoxylan catabolic process [GO:2000886]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	extracellular region [GO:0005576]		alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d1mr5a1_d1wcsa1__1					exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]			exo-alpha-sialidase activity [GO:0004308]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1mr5a1_d3pvoq___1		Metazoa		Chordata	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	pathogenesis [GO:0009405]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	exo-alpha-sialidase activity [GO:0004308]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1mr7b__d4e8lb___1			Firmicutes		transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]				transferase activity, transferring acyl groups [GO:0016746]	
d1mr7b__d5depc___1			Firmicutes	Proteobacteria	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	response to antibiotic [GO:0046677]	lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups [GO:0016746]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]
d1mr8a__d1gqmf___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d1mraa1_d3es7a2__1			Proteobacteria	Firmicutes	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]				mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]
d1mrfl1_d1mcsb1__1												
d1mrfl2_d1yylr2__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1mrla__d2v0la2__1			Firmicutes	Proteobacteria	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	response to antibiotic [GO:0046677]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups [GO:0016746]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d1mrlb__d1ocxa___1			Firmicutes	Proteobacteria	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; maltose O-acetyltransferase activity [GO:0008925]; protein homotrimerization [GO:0070207]	response to antibiotic [GO:0046677]	protein homotrimerization [GO:0070207]		cytosol [GO:0005829]	transferase activity, transferring acyl groups [GO:0016746]	identical protein binding [GO:0042802]; maltose O-acetyltransferase activity [GO:0008925]
d1mrwb__d1fq5a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]; autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]
d1mrxa__d3sqfa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	viral nucleocapsid [GO:0019013]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d1mrxa__d5p3aa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1mrxb__d5p7ba___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1mrzb2_d1vlhb___1			Thermotogae	Thermotogae	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]; FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1ms0a1_d1wblc___1		Viridiplantae		Streptophyta	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	carbohydrate binding [GO:0030246]	pathogenesis [GO:0009405]				exo-alpha-sialidase activity [GO:0004308]	carbohydrate binding [GO:0030246]
d1ms0b1_d1cq9b___1		Viridiplantae		Streptophyta	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	pathogenesis [GO:0009405]				exo-alpha-sialidase activity [GO:0004308]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1ms0b2_d4mwxa___1				Negarnaviricota	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-sialidase activity [GO:0004308]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1ms4a2_d2htyh___1				Negarnaviricota	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-sialidase activity [GO:0004308]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1ms4b2_d3k39e___1				Negarnaviricota	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-sialidase activity [GO:0004308]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1ms5a1_d1b09c___1		Metazoa		Chordata	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	pathogenesis [GO:0009405]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	exo-alpha-sialidase activity [GO:0004308]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1ms5a1_d1n1ya1__1					exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]			exo-alpha-sialidase activity [GO:0004308]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1ms8a1_d2z42a1__1				Proteobacteria	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	lyase activity [GO:0016829]	pathogenesis [GO:0009405]				exo-alpha-sialidase activity [GO:0004308]	lyase activity [GO:0016829]
d1ms8b2_d4gezi___1				Negarnaviricota	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-sialidase activity [GO:0004308]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1ms9b1_d1gbga___1				Firmicutes	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]			exo-alpha-sialidase activity [GO:0004308]	licheninase activity [GO:0042972]
d1msaa__d5t20f___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; mannose binding [GO:0005537]				extracellular region [GO:0005576]		mannose binding [GO:0005537]	
d1msab__d5t20g___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; mannose binding [GO:0005537]				extracellular region [GO:0005576]		mannose binding [GO:0005537]	
d1msac__d1xd5d___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; mannose binding [GO:0005537]				extracellular region [GO:0005576]		mannose binding [GO:0005537]	
d1msba__d2zwka2__1	Metazoa		Chordata	Proteobacteria	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	
d1msda1_d1kkcb1__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1msda1_d4h3ea1__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1msda2_d4f2nl2__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1msdb2_d4gune2__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1msja__d1ucsa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]	extracellular region [GO:0005576]			extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1msnb__d5oz7a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1mspa__d1klfg1__1	Metazoa		Nematoda (roundworms)	Proteobacteria	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d1mssa__d2yc8j___1					cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]; glycosome [GO:0020015]		triose-phosphate isomerase activity [GO:0004807]	
d1mt7a__d5p1da___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1mtba__d2avob___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1mtca2_d2cvdb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1mtca2_d4mh2h___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d1mtoa__d4i4id___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; 6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; fructose 6-phosphate metabolic process [GO:0006002]	cytoplasm [GO:0005737]; 6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; fructose 6-phosphate metabolic process [GO:0006002]	fructose 6-phosphate metabolic process [GO:0006002]	fructose 6-phosphate metabolic process [GO:0006002]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]	6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d1mtva__d3sueb___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1mtwa__d5dp4b1__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1mtyb__d5jkkh___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1mtye__d5d8ys___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1mtza__d3aimc___1			Euryarchaeota	Crenarchaeota	aminopeptidase activity [GO:0004177]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]					aminopeptidase activity [GO:0004177]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]
d1mu0a__d3a2nb___1			Euryarchaeota	Proteobacteria	aminopeptidase activity [GO:0004177]	haloalkane dehalogenase activity [GO:0018786]; identical protein binding [GO:0042802]					aminopeptidase activity [GO:0004177]	haloalkane dehalogenase activity [GO:0018786]; identical protein binding [GO:0042802]
d1mu2a1_d4huea___1				Firmicutes	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1mu2a1_d4puoc2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1mu4a1_d1hdna___1			Firmicutes	Proteobacteria		cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]; enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]		phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]		cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]		enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]
d1mu4a1_d3lnwb___1			Firmicutes	Firmicutes		cytoplasm [GO:0005737]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]		phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]		cytoplasm [GO:0005737]		transferase activity [GO:0016740]
d1mu4b1_d1ggrb___1			Firmicutes	Proteobacteria		cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]; enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]		phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]		cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]		enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]
d1muca1_d1sjca1__1			Proteobacteria	Actinobacteria	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; beta-ketoadipate pathway [GO:0042952]; cellular amino acid catabolic process [GO:0009063]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	beta-ketoadipate pathway [GO:0042952]; cellular amino acid catabolic process [GO:0009063]	menaquinone biosynthetic process [GO:0009234]			chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d1muib__d5p7za___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1muja1_d1mcsb1__1	Metazoa		Chordata		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	
d1muja1_d5ddhb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1muja2_d1t5wb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1mumb__d1u5va___1			Proteobacteria	Actinobacteria	magnesium ion binding [GO:0000287]; methylisocitrate lyase activity [GO:0046421]; propionate catabolic process, 2-methylcitrate cycle [GO:0019629]	lyase activity [GO:0016829]; magnesium ion binding [GO:0000287]; oxaloacetate metabolic process [GO:0006107]	propionate catabolic process, 2-methylcitrate cycle [GO:0019629]	oxaloacetate metabolic process [GO:0006107]			magnesium ion binding [GO:0000287]; methylisocitrate lyase activity [GO:0046421]	lyase activity [GO:0016829]; magnesium ion binding [GO:0000287]
d1mupa__d2fs7a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1muqb__d1kzb1___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]		complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]
d1muta__d4kg3a___1		Fungi	Proteobacteria	Ascomycota	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; Dcp1-Dcp2 complex [GO:0098745]; nucleus [GO:0005634]; P-body [GO:0000932]; chromatin binding [GO:0003682]; hydrolase activity [GO:0016787]; m7G(5')pppN diphosphatase activity [GO:0050072]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; mRNA processing [GO:0006397]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; stress granule assembly [GO:0034063]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; mRNA processing [GO:0006397]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; stress granule assembly [GO:0034063]		cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; Dcp1-Dcp2 complex [GO:0098745]; nucleus [GO:0005634]; P-body [GO:0000932]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]	chromatin binding [GO:0003682]; hydrolase activity [GO:0016787]; m7G(5')pppN diphosphatase activity [GO:0050072]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]
d1muya__d1wefa___1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]			4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]
d1mv5a__d1ojlb___1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled xenobiotic transmembrane transporter activity [GO:0008559]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	response to antibiotic [GO:0046677]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase-coupled xenobiotic transmembrane transporter activity [GO:0008559]; ATP binding [GO:0005524]	ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d1mv8c2_d3qwfc___1		Fungi	Proteobacteria	Ascomycota	GDP-mannose 6-dehydrogenase activity [GO:0047919]; NAD binding [GO:0051287]; alginic acid biosynthetic process [GO:0042121]; cellular response to cell envelope stress [GO:0036460]; response to osmotic stress [GO:0006970]; single-species biofilm formation [GO:0044010]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	alginic acid biosynthetic process [GO:0042121]; cellular response to cell envelope stress [GO:0036460]; response to osmotic stress [GO:0006970]; single-species biofilm formation [GO:0044010]				GDP-mannose 6-dehydrogenase activity [GO:0047919]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1mvga__d1gt1a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]		response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	lipid binding [GO:0008289]	small molecule binding [GO:0036094]
d1mvoa__d4nicc___1			Firmicutes		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphate ion transport [GO:0006817]		phosphate ion transport [GO:0006817]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	
d1mvsa__d2c2ta___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1mvua__d5alcl2__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; ATPase-coupled xenobiotic transmembrane transporter activity [GO:0008559]; ceramide floppase activity [GO:0099038]; efflux transmembrane transporter activity [GO:0015562]; floppase activity [GO:0140328]; phosphatidylcholine floppase activity [GO:0090554]; phosphatidylethanolamine flippase activity [GO:0090555]; xenobiotic transmembrane transporter activity [GO:0042910]; phospholipid translocation [GO:0045332]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transport across blood-brain barrier [GO:1990962]		phospholipid translocation [GO:0045332]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transport across blood-brain barrier [GO:1990962]		apical plasma membrane [GO:0016324]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]		ATPase activity, coupled [GO:0042623]; ATPase-coupled xenobiotic transmembrane transporter activity [GO:0008559]; ATP binding [GO:0005524]; ceramide floppase activity [GO:0099038]; efflux transmembrane transporter activity [GO:0015562]; floppase activity [GO:0140328]; phosphatidylcholine floppase activity [GO:0090554]; phosphatidylethanolamine flippase activity [GO:0090555]; xenobiotic transmembrane transporter activity [GO:0042910]	
d1mvya1_d5e70d3__1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	extracellular region [GO:0005576]	cytosol [GO:0005829]	amylosucrase activity [GO:0047669]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1mvya2_d2f2hb4__1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		amylosucrase activity [GO:0047669]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1mw0a2_d2wbgd___1			Proteobacteria	Thermotogae	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		amylosucrase activity [GO:0047669]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1mw2a1_d3h53a2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	amylosucrase activity [GO:0047669]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d1mw3a2_d2rgla___1		Viridiplantae	Proteobacteria	Streptophyta	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	amylosucrase activity [GO:0047669]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d1mwaa1_d1hcfx___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	axon [GO:0030424]; axon terminus [GO:0043679]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; brain-derived neurotrophic factor binding [GO:0048403]; brain-derived neurotrophic factor-activated receptor activity [GO:0060175]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of phospholipase C activity [GO:0007202]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cellular response to amino acid stimulus [GO:0071230]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; circadian rhythm [GO:0007623]; feeding behavior [GO:0007631]; glutamate secretion [GO:0014047]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuronal action potential propagation [GO:0019227]; neurotrophin TRK receptor signaling pathway [GO:0048011]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system neuron development [GO:0048935]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; retinal rod cell development [GO:0046548]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trans-synaptic signaling by neuropeptide, modulating synaptic transmission [GO:0099551]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	activation of phospholipase C activity [GO:0007202]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cellular response to amino acid stimulus [GO:0071230]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; circadian rhythm [GO:0007623]; feeding behavior [GO:0007631]; glutamate secretion [GO:0014047]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neuronal action potential propagation [GO:0019227]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neurotrophin TRK receptor signaling pathway [GO:0048011]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system neuron development [GO:0048935]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; retinal rod cell development [GO:0046548]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trans-synaptic signaling by neuropeptide, modulating synaptic transmission [GO:0099551]; vasculogenesis [GO:0001570]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	axon [GO:0030424]; axon terminus [GO:0043679]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	ATP binding [GO:0005524]; brain-derived neurotrophic factor-activated receptor activity [GO:0060175]; brain-derived neurotrophic factor binding [GO:0048403]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1mwac1_d1h3ya2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1mwad2_d5kg9b2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1mwah1_d3of6b2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	integral component of membrane [GO:0016021]; negative regulation of thymocyte apoptotic process [GO:0070244]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	negative regulation of thymocyte apoptotic process [GO:0070244]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1mwai1_d1op5l2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1mwam__d5kveh1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1mwda__d3uh7a___1	Metazoa	Metazoa	Chordata	Mollusca	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1mwja__d5ayrc1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; pyrimidine-specific mismatch base pair DNA N-glycosylase activity [GO:0008263]; base-excision repair, AP site formation [GO:0006285]	metal ion binding [GO:0046872]	base-excision repair, AP site formation [GO:0006285]		cytoplasm [GO:0005737]		DNA binding [GO:0003677]; pyrimidine-specific mismatch base pair DNA N-glycosylase activity [GO:0008263]	metal ion binding [GO:0046872]
d1mwkb1_d1x9jb2__1			Proteobacteria	Thermotogae	identical protein binding [GO:0042802]; plasmid partitioning [GO:0030541]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	plasmid partitioning [GO:0030541]			cytoplasm [GO:0005737]	identical protein binding [GO:0042802]	ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]
d1mwma2_d3wxia1__1			Proteobacteria		identical protein binding [GO:0042802]; plasmid partitioning [GO:0030541]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	plasmid partitioning [GO:0030541]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]			identical protein binding [GO:0042802]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d1mwna__d3ucwd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1mwnb__d1xfvo1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1mwoa2_d3t2pb3__1			Euryarchaeota	Proteobacteria	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1mwsa2_d3pbta1__1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; response to antibiotic [GO:0046677]	integral component of plasma membrane [GO:0005887]; penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall organization [GO:0071555]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	response to antibiotic [GO:0046677]	cell wall organization [GO:0071555]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	integral component of membrane [GO:0016021]	integral component of plasma membrane [GO:0005887]	penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]	penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]
d1mwta1_d2geyb___1			Firmicutes	Actinobacteria	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; response to antibiotic [GO:0046677]	polyketide metabolic process [GO:0030638]	response to antibiotic [GO:0046677]	polyketide metabolic process [GO:0030638]	integral component of membrane [GO:0016021]		penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]	
d1mwta2_d3pbsa1__1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; response to antibiotic [GO:0046677]	integral component of plasma membrane [GO:0005887]; penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall organization [GO:0071555]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	response to antibiotic [GO:0046677]	cell wall organization [GO:0071555]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	integral component of membrane [GO:0016021]	integral component of plasma membrane [GO:0005887]	penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]	penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]
d1mwwa__d4wr8h___1		Metazoa	Proteobacteria	Chordata		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d1mwwb__d4wr8f___1		Metazoa	Proteobacteria	Chordata		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d1mwya__d1afia___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; cadmium ion transmembrane transporter activity [GO:0015086]; cadmium transmembrane transporter activity, phosphorylative mechanism [GO:0008551]; cobalt ion transmembrane transporter activity [GO:0015087]; lead ion transmembrane transporter activity [GO:0015094]; metal ion binding [GO:0046872]; nickel cation transmembrane transporter activity [GO:0015099]; zinc ion transmembrane transporter activity [GO:0005385]; zinc transmembrane transporter activity, phosphorylative mechanism [GO:0016463]; cobalt ion transport [GO:0006824]; detoxification of zinc ion [GO:0010312]; lead ion transport [GO:0015692]; response to cadmium ion [GO:0046686]; zinc ion transport [GO:0006829]	periplasmic space [GO:0042597]; mercury ion binding [GO:0045340]; mercury ion transmembrane transporter activity [GO:0015097]	cobalt ion transport [GO:0006824]; detoxification of zinc ion [GO:0010312]; lead ion transport [GO:0015692]; response to cadmium ion [GO:0046686]; zinc ion transport [GO:0006829]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; cadmium ion transmembrane transporter activity [GO:0015086]; cadmium transmembrane transporter activity, phosphorylative mechanism [GO:0008551]; cobalt ion transmembrane transporter activity [GO:0015087]; lead ion transmembrane transporter activity [GO:0015094]; metal ion binding [GO:0046872]; nickel cation transmembrane transporter activity [GO:0015099]; zinc ion transmembrane transporter activity [GO:0005385]; zinc transmembrane transporter activity, phosphorylative mechanism [GO:0016463]	mercury ion binding [GO:0045340]; mercury ion transmembrane transporter activity [GO:0015097]
d1mx1c__d3ls2a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]; formaldehyde catabolic process [GO:0046294]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	formaldehyde catabolic process [GO:0046294]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]		carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]
d1mx1d__d2hada___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]		carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	haloalkane dehalogenase activity [GO:0018786]
d1mx3a1_d1v8bc1__1	Metazoa		Chordata	Apicomplexa	GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; presynaptic active zone cytoplasmic component [GO:0098831]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; chromatin silencing [GO:0006342]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H4 acetylation [GO:0090241]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of histone deacetylation [GO:0031065]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; viral genome replication [GO:0019079]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]; adenosylhomocysteinase activity [GO:0004013]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353]	chromatin silencing [GO:0006342]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H4 acetylation [GO:0090241]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; viral genome replication [GO:0019079]; white fat cell differentiation [GO:0050872]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353]	GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; presynaptic active zone cytoplasmic component [GO:0098831]; transcriptional repressor complex [GO:0017053]	cytosol [GO:0005829]	chromatin binding [GO:0003682]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]	adenosylhomocysteinase activity [GO:0004013]
d1mx5c__d4b6ga1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]; formaldehyde catabolic process [GO:0046294]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	formaldehyde catabolic process [GO:0046294]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	cytosol [GO:0005829]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]
d1mx5e__d2xlbk___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	acetylesterase activity [GO:0008126]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]		carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	acetylesterase activity [GO:0008126]
d1mx6a__d3twqa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]; cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of phosphorylation [GO:0042326]; oligodendrocyte differentiation [GO:0048709]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of phosphorylation [GO:0042326]; oligodendrocyte differentiation [GO:0048709]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]
d1mx8a__d3nq9a___1	Metazoa	Metazoa	Chordata	Chordata	cell body [GO:0044297]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; lipid homeostasis [GO:0055088]; regulation of granulocyte differentiation [GO:0030852]; response to vitamin A [GO:0033189]; retinoic acid biosynthetic process [GO:0002138]; retinol metabolic process [GO:0042572]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	lipid homeostasis [GO:0055088]; regulation of granulocyte differentiation [GO:0030852]; response to vitamin A [GO:0033189]; retinoic acid biosynthetic process [GO:0002138]; retinol metabolic process [GO:0042572]; vitamin A metabolic process [GO:0006776]		cell body [GO:0044297]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]	all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinol binding [GO:0019841]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]
d1mx9b__d4a5sb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1mx9f__d2xlbf___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	acetylesterase activity [GO:0008126]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]		carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	acetylesterase activity [GO:0008126]
d1mx9g__d3sx4b2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1mx9j__d5jkfb___1	Metazoa		Chordata		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; cellular amino acid biosynthetic process [GO:0008652]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cellular amino acid biosynthetic process [GO:0008652]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1mxaa1_d1p7la2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d1mxaa2_d1o90a2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]
d1mxba2_d5ughb1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d1mxca2_d5a19a1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d1mxia__d3aiaa1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; tRNA methyltransferase activity [GO:0008175]; wobble position cytosine ribose methylation [GO:0002131]; wobble position uridine ribose methylation [GO:0002132]	cytoplasm [GO:0005737]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; tRNA methyltransferase activity [GO:0008175]; tRNA methylation [GO:0030488]	wobble position cytosine ribose methylation [GO:0002131]; wobble position uridine ribose methylation [GO:0002132]	tRNA methylation [GO:0030488]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; tRNA methyltransferase activity [GO:0008175]	S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; tRNA methyltransferase activity [GO:0008175]
d1mxsa__d1xxxc___1			Proteobacteria	Actinobacteria	2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1mxta2_d1pbca2__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	cholesterol metabolic process [GO:0008203]	benzoate catabolic process via hydroxylation [GO:0043640]	extracellular region [GO:0005576]		cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1mxua__d5cryb___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d1mxub__d4mh5a1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1mxuc__d4io4b1__1	Metazoa	Metazoa	Chordata	Rotifera (rotifers)	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	integral component of membrane [GO:0016021]; G protein-coupled receptor activity [GO:0004930]; ligand-gated ion channel activity [GO:0015276]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	integral component of membrane [GO:0016021]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	G protein-coupled receptor activity [GO:0004930]; ligand-gated ion channel activity [GO:0015276]
d1mxwa__d3gyyd___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d1mxxa__d1t0ka1__1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1mxzb__d5ftia___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1my0a__d2uvia___1	Metazoa		Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d1my2b__d1dota1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	extracellular space [GO:0005615]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	metal ion binding [GO:0046872]
d1my2c__d1n7wa___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d1my2c__d5elvb1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1my3a__d4qhqa___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d1my3b__d3tkda1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1my3c__d1jeua___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	protein transport [GO:0015031]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	peptide transmembrane transporter activity [GO:1904680]
d1my5a__d1ut9a2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose catabolic process [GO:0030245]	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cellulose catabolic process [GO:0030245]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]		actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]	cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]
d1my6a2_d1ar4b2__1			Cyanobacteria	Actinobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1my6b2_d2a03b2__1			Cyanobacteria		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]						metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	
d1my7a__d4l5fe___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]	protein dimerization activity [GO:0046983]
d1my7b__d5gzna2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1myha__d1y7zc___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1myhb__d1yhut___1	Metazoa	Metazoa	Chordata	Annelida	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1myja__d2evpa___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1myp.1_d5jhyb1__1	Metazoa	Fungi	Chordata	Ascomycota	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]; chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	extracellular region [GO:0005576]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]	extracellular region [GO:0005576]	chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1myra__d4pmya___1	Viridiplantae		Streptophyta	Proteobacteria	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	vacuole [GO:0005773]		glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]
d1mz5a2_d1v0fe1__1					exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]		virus tail, fiber [GO:0098024]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]
d1mzaa__d1c1oa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1mzcb__d1h3ca2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]; protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]; protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	hopanoid biosynthetic process [GO:0019746]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1mzhb1_d2nx3g___1			Aquificae	Aquificae	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	deoxyribose-phosphate aldolase activity [GO:0004139]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]
d1mzja2_d4xoxa1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1mzjb2_d1chwb2__1		Viridiplantae	Actinobacteria	Streptophyta	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	naringenin-chalcone synthase activity [GO:0016210]
d1mzjb2_d4wyra1__1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]	fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1mzma__d1bwob___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid transport [GO:0006869]	lipid transport [GO:0006869]			lipid binding [GO:0008289]	lipid binding [GO:0008289]
d1mzma__d1tmqb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lipid binding [GO:0008289]; lipid transport [GO:0006869]	extracellular region [GO:0005576]; alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]	lipid transport [GO:0006869]			extracellular region [GO:0005576]	lipid binding [GO:0008289]	alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]
d1mzoa__d1r1ra2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; formate C-acetyltransferase activity [GO:0008861]; glucose metabolic process [GO:0006006]; threonine catabolic process [GO:0006567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	glucose metabolic process [GO:0006006]; threonine catabolic process [GO:0006567]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	formate C-acetyltransferase activity [GO:0008861]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1mzra__d2iqda___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; 2,5-didehydrogluconate reductase activity [GO:0050580]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; L-ascorbic acid biosynthetic process [GO:0019853]; methylglyoxal catabolic process [GO:0051596]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	L-ascorbic acid biosynthetic process [GO:0019853]; methylglyoxal catabolic process [GO:0051596]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	2,5-didehydrogluconate reductase activity [GO:0050580]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d1mzsa2_d1tvza2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	isoprenoid biosynthetic process [GO:0008299]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d1mzub__d2o9ca2__1			Proteobacteria	Deinococcus-Thermus	phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; detection of visible light [GO:0009584]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d1mzva__d1bd3b___1				Apicomplexa	adenine phosphoribosyltransferase activity [GO:0003999]; nucleotide binding [GO:0000166]; nucleoside metabolic process [GO:0009116]	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]			adenine phosphoribosyltransferase activity [GO:0003999]; nucleotide binding [GO:0000166]	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]
d1mzwa__d2a2nc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U4/U6 snRNP [GO:0071001]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; ribonucleoprotein complex binding [GO:0043021]; unfolded protein binding [GO:0051082]; angiogenesis [GO:0001525]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; protein-containing complex assembly [GO:0065003]	catalytic step 2 spliceosome [GO:0071013]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; mRNA splicing, via spliceosome [GO:0000398]; protein peptidyl-prolyl isomerization [GO:0000413]	angiogenesis [GO:0001525]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein-containing complex assembly [GO:0065003]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]	mRNA splicing, via spliceosome [GO:0000398]; protein peptidyl-prolyl isomerization [GO:0000413]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U4/U6 snRNP [GO:0071001]; U4/U6 x U5 tri-snRNP complex [GO:0046540]	catalytic step 2 spliceosome [GO:0071013]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; ribonucleoprotein complex binding [GO:0043021]; unfolded protein binding [GO:0051082]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1mzya2_d1waea2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1mzza2_d1vlxa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1mzzb1_d2h3xf___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; amine dehydrogenase activity [GO:0030058]; aralkylamine dehydrogenase (azurin) activity [GO:0030059]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	amine dehydrogenase activity [GO:0030058]; aralkylamine dehydrogenase (azurin) activity [GO:0030059]
d1mzzb2_d2i7sb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1mzzb2_d3nt0a2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d1mzzc2_d2xv3a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1n00a1_d1bc0a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; fruit ripening [GO:0009835]; oxidation-reduction process [GO:0055114]; regulation of cellulose biosynthetic process [GO:2001006]; response to oxidative stress [GO:0006979]; secretion by cell [GO:0032940]	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	fruit ripening [GO:0009835]; oxidation-reduction process [GO:0055114]; regulation of cellulose biosynthetic process [GO:2001006]; response to oxidative stress [GO:0006979]; secretion by cell [GO:0032940]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	integral component of membrane [GO:0016021]	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]
d1n04a2_d1gv8a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	extracellular space [GO:0005615]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]	metal ion binding [GO:0046872]
d1n04a2_d4q30f___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1n06b__d2oyna1__1	Fungi		Ascomycota	Euryarchaeota	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; ATP binding [GO:0005524]; riboflavin kinase activity [GO:0008531]; zinc ion binding [GO:0008270]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; riboflavin kinase activity [GO:0008531]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]		ATP binding [GO:0005524]; riboflavin kinase activity [GO:0008531]; zinc ion binding [GO:0008270]	magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; riboflavin kinase activity [GO:0008531]
d1n0ha2_d2wvga1__1	Fungi		Ascomycota	Proteobacteria	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1n0ja2_d1bt8a2__1	Metazoa		Chordata	Actinobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1n0jb1_d3liob1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1n0nb1_d4gunp1__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1n0sb__d1fe3a___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; pigment binding [GO:0031409]; protein-chromophore linkage [GO:0018298]	cell periphery [GO:0071944]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; lipid binding [GO:0008289]; cell proliferation in forebrain [GO:0021846]; epithelial cell proliferation [GO:0050673]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]; triglyceride catabolic process [GO:0019433]	protein-chromophore linkage [GO:0018298]	cell proliferation in forebrain [GO:0021846]; epithelial cell proliferation [GO:0050673]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	cell-cell junction [GO:0005911]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	pigment binding [GO:0031409]	lipid binding [GO:0008289]
d1n0ta__d4eqba___1	Metazoa		Chordata	Firmicutes	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; polyamine binding [GO:0019808]; polyamine transport [GO:0015846]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	polyamine transport [GO:0015846]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	metal ion binding [GO:0046872]; polyamine binding [GO:0019808]
d1n0ta__d4khze___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1n0td__d3c36a___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d1n0ua3_d1p42b2__1	Fungi		Ascomycota	Aquificae	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d1n0vc1_d4rd4a2__1	Fungi		Ascomycota	Crenarchaeota	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1n0vc3_d5elwa2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	histidine biosynthetic process [GO:0000105]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]	chloroplast [GO:0009507]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d1n0vd1_d3d5be1__1	Fungi		Ascomycota		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]	
d1n0vd4_d2zita5__1	Fungi		Ascomycota	Proteobacteria	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d1n0vd5_d1zm2a4__1	Fungi		Ascomycota	Proteobacteria	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d1n0xm2_d2ntfa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1n0ya__d1odbe1__1		Metazoa	Ciliophora	Chordata	calcium ion binding [GO:0005509]; calcium-mediated signaling [GO:0019722]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	calcium-mediated signaling [GO:0019722]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d1n0yb__d2w73f___1		Metazoa	Ciliophora	Chordata	calcium ion binding [GO:0005509]; calcium-mediated signaling [GO:0019722]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	calcium-mediated signaling [GO:0019722]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1n10a1_d1whpa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; sexual reproduction [GO:0019953]	extracellular region [GO:0005576]	sexual reproduction [GO:0019953]		extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1n13.2_d1pya.2__1			Euryarchaeota	Firmicutes	arginine decarboxylase activity [GO:0008792]; arginine catabolic process [GO:0006527]	histidine decarboxylase activity [GO:0004398]; histidine metabolic process [GO:0006547]	arginine catabolic process [GO:0006527]	histidine metabolic process [GO:0006547]			arginine decarboxylase activity [GO:0008792]	histidine decarboxylase activity [GO:0004398]
d1n13.3_d1n13.6__1			Euryarchaeota	Euryarchaeota	arginine decarboxylase activity [GO:0008792]; arginine catabolic process [GO:0006527]	arginine decarboxylase activity [GO:0008792]; arginine catabolic process [GO:0006527]	arginine catabolic process [GO:0006527]	arginine catabolic process [GO:0006527]			arginine decarboxylase activity [GO:0008792]	arginine decarboxylase activity [GO:0008792]
d1n13.3_d1pya.1__1			Euryarchaeota	Firmicutes	arginine decarboxylase activity [GO:0008792]; arginine catabolic process [GO:0006527]	histidine decarboxylase activity [GO:0004398]; histidine metabolic process [GO:0006547]	arginine catabolic process [GO:0006527]	histidine metabolic process [GO:0006547]			arginine decarboxylase activity [GO:0008792]	histidine decarboxylase activity [GO:0004398]
d1n16a4_d3zxrd2__1				Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1n16b3_d1m15a1__1		Metazoa		Arthropoda		cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]		arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d1n18a__d3gttb___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; aging [GO:0007568]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to nutrient levels [GO:0031667]; response to organic substance [GO:0010033]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to nutrient levels [GO:0031667]; response to organic substance [GO:0010033]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1n18d__d1sxcb___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1n18f__d5k02c___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1n18h__d2jlpc___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; heparin binding [GO:0008201]; superoxide dismutase activity [GO:0004784]; cellular response to oxidative stress [GO:0034599]; removal of superoxide radicals [GO:0019430]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cellular response to oxidative stress [GO:0034599]; removal of superoxide radicals [GO:0019430]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; heparin binding [GO:0008201]; superoxide dismutase activity [GO:0004784]
d1n1db__d2b7lc___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cytoplasm [GO:0005737]; glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]	glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]
d1n1dd__d1j70a2__1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1n1dd__d2b7lb___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cytoplasm [GO:0005737]; glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]	glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]
d1n1l.2_d2snva___1					cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]
d1n1qb__d2x171___1			Firmicutes	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d1n1qb__d3isei___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1n1qc__d1ryta1__1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]	cytoplasm [GO:0005737]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]		cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1n1sa2_d1a14n___1				Negarnaviricota	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1n1ta1_d1teic___1		Viridiplantae		Streptophyta	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]				exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1n1ta2_d1usrb___1				Negarnaviricota	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]
d1n1va2_d2hu4b___1				Negarnaviricota	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1n1ya1_d2dv9d___1		Viridiplantae		Streptophyta	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]				exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1n1ya2_d4qn4a___1				Negarnaviricota	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1n20b2_d1v4ha___1	Viridiplantae		Streptophyta	Thermotogae	chloroplast [GO:0009507]; camphene synthase activity [GO:0102703]; geranyl-diphosphate cyclase activity [GO:0047926]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; terpene synthase activity [GO:0010333]; (+)-camphor biosynthetic process [GO:0046211]	transferase activity [GO:0016740]; isoprenoid biosynthetic process [GO:0008299]	(+)-camphor biosynthetic process [GO:0046211]	isoprenoid biosynthetic process [GO:0008299]	chloroplast [GO:0009507]		camphene synthase activity [GO:0102703]; geranyl-diphosphate cyclase activity [GO:0047926]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; terpene synthase activity [GO:0010333]	transferase activity [GO:0016740]
d1n21a2_d5eata2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; camphene synthase activity [GO:0102703]; geranyl-diphosphate cyclase activity [GO:0047926]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; terpene synthase activity [GO:0010333]; (+)-camphor biosynthetic process [GO:0046211]	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	(+)-camphor biosynthetic process [GO:0046211]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]	camphene synthase activity [GO:0102703]; geranyl-diphosphate cyclase activity [GO:0047926]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; terpene synthase activity [GO:0010333]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d1n23b2_d3wchf___1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; camphene synthase activity [GO:0102703]; geranyl-diphosphate cyclase activity [GO:0047926]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; terpene synthase activity [GO:0010333]; (+)-camphor biosynthetic process [GO:0046211]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	(+)-camphor biosynthetic process [GO:0046211]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	chloroplast [GO:0009507]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	camphene synthase activity [GO:0102703]; geranyl-diphosphate cyclase activity [GO:0047926]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; terpene synthase activity [GO:0010333]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d1n26a3_d3bpob1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; ciliary neurotrophic factor receptor complex [GO:0070110]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor binding [GO:0070119]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; enzyme binding [GO:0019899]; interleukin-6 binding [GO:0019981]; interleukin-6 receptor activity [GO:0004915]; protein homodimerization activity [GO:0042803]; acute-phase response [GO:0006953]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; endocrine pancreas development [GO:0031018]; extrinsic apoptotic signaling pathway [GO:0097191]; hepatic immune response [GO:0002384]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of interleukin-8 production [GO:0032717]; neutrophil mediated immunity [GO:0002446]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of glomerular mesangial cell proliferation [GO:0072126]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to cytokine [GO:0034097]	external side of plasma membrane [GO:0009897]; interleukin-13 receptor complex [GO:0005898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-2 binding [GO:0019976]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]	acute-phase response [GO:0006953]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; endocrine pancreas development [GO:0031018]; extrinsic apoptotic signaling pathway [GO:0097191]; hepatic immune response [GO:0002384]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of interleukin-8 production [GO:0032717]; neutrophil mediated immunity [GO:0002446]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of glomerular mesangial cell proliferation [GO:0072126]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to cytokine [GO:0034097]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; ciliary neurotrophic factor receptor complex [GO:0070110]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	external side of plasma membrane [GO:0009897]; interleukin-13 receptor complex [GO:0005898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	ciliary neurotrophic factor binding [GO:0070119]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; enzyme binding [GO:0019899]; interleukin-6 binding [GO:0019981]; interleukin-6 receptor activity [GO:0004915]; protein homodimerization activity [GO:0042803]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-2 binding [GO:0019976]
d1n2cb__d4utpa1__1			Proteobacteria	Firmicutes	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	nitrogen fixation [GO:0009399]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	molybdenum-iron nitrogenase complex [GO:0016612]	plasma membrane [GO:0005886]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	metal ion binding [GO:0046872]
d1n2cc__d5bvhc___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1n2da__d2jc2d___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; MIH complex [GO:0120155]; myosin II complex [GO:0016460]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; myosin II heavy chain binding [GO:0032038]; myosin V binding [GO:0031489]; actomyosin contractile ring assembly [GO:0000915]; protein localization [GO:0008104]; vesicle targeting [GO:0006903]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]; action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	actomyosin contractile ring assembly [GO:0000915]; protein localization [GO:0008104]; vesicle targeting [GO:0006903]	action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; MIH complex [GO:0120155]; myosin II complex [GO:0016460]; vesicle [GO:0031982]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; myosin II heavy chain binding [GO:0032038]; myosin V binding [GO:0031489]	calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]
d1n2ia__d1mrza2__1			Actinobacteria	Thermotogae	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]; beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]; FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]
d1n2ma__d1ibw.3__1			Euryarchaeota	Firmicutes	arginine decarboxylase activity [GO:0008792]; arginine catabolic process [GO:0006527]	histidine decarboxylase activity [GO:0004398]; histidine metabolic process [GO:0006547]	arginine catabolic process [GO:0006527]	histidine metabolic process [GO:0006547]			arginine decarboxylase activity [GO:0008792]	histidine decarboxylase activity [GO:0004398]
d1n2ra2_d5w1wa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1n2sa__d2hrba1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; dTDP-4-dehydrorhamnose reductase activity [GO:0008831]; metal ion binding [GO:0046872]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; 3-keto sterol reductase activity [GO:0000253]; carbonyl reductase (NADPH) activity [GO:0004090]; NADPH binding [GO:0070402]; cognition [GO:0050890]; phylloquinone catabolic process [GO:0042376]; xenobiotic metabolic process [GO:0006805]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	cognition [GO:0050890]; phylloquinone catabolic process [GO:0042376]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	dTDP-4-dehydrorhamnose reductase activity [GO:0008831]; metal ion binding [GO:0046872]	3-keto sterol reductase activity [GO:0000253]; carbonyl reductase (NADPH) activity [GO:0004090]; NADPH binding [GO:0070402]
d1n2tb1_d1i41k___1		Viridiplantae	Cyanobacteria	Streptophyta	lyase activity [GO:0016829]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]		transsulfuration [GO:0019346]			lyase activity [GO:0016829]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d1n2za__d1m34c___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; cobalamin binding [GO:0031419]; cobalamin transport [GO:0015889]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cobalamin transport [GO:0015889]	nitrogen fixation [GO:0009399]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	molybdenum-iron nitrogenase complex [GO:0016612]	cobalamin binding [GO:0031419]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1n2zb__d4nd8d___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; cobalamin binding [GO:0031419]; cobalamin transport [GO:0015889]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cobalamin transport [GO:0015889]	nitrogen fixation [GO:0009399]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	molybdenum-iron nitrogenase complex [GO:0016612]	cobalamin binding [GO:0031419]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1n32c1_d3ieub2__1			Deinococcus-Thermus	Proteobacteria	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; small ribosomal subunit rRNA binding [GO:0070181]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]	translation [GO:0006412]	protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]	ribosome [GO:0005840]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; small ribosomal subunit rRNA binding [GO:0070181]
d1n32q__d4ipha1__1		Metazoa	Deinococcus-Thermus	Chordata	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]; damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	translation [GO:0006412]	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	ribosome [GO:0005840]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]
d1n33i__d2qp0i1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1n34e1_d3wu5b___1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1n36s__d3df1s1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1n3aa1_d4aiae1__1	Metazoa		Chordata		mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]		acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]		mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	
d1n3ca1_d4ai5b___1	Metazoa		Chordata		mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]		acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]		mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	
d1n3nf__d3g04a2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]; activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]
d1n3ng1_d2j4wh1__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	membrane [GO:0016020]; pathogenesis [GO:0009405]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	pathogenesis [GO:0009405]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	membrane [GO:0016020]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1n3ng2_d1kpua2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1n3nh__d1ad9b1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1n3qa__d2nlra___1	Viridiplantae		Streptophyta	Actinobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]
d1n3ra__d2yzeg2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1n3rd__d5m98b2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1n3re__d3obpa2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1n3rf__d4mb8a2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1n3rh__d4puva1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1n3rj__d1a9ch___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1n3rm__d1ws2a2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1n3rn__d1n3sb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1n3se__d2obae1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]; queuosine biosynthetic process [GO:0008616]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	queuosine biosynthetic process [GO:0008616]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]
d1n3sg__d1b9lf___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]; folic acid-containing compound metabolic process [GO:0006760]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]
d1n3si__d1ws2d2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1n3si__d1wure___1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1n3tc__d3qnaf___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	queuosine biosynthetic process [GO:0008616]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d1n3td__d3gkoa1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1n3te__d4cw0a1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1n3tg__d1fbxl___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1n3tg__d1vaxh1__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	
d1n3ti__d5ll1e1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1n3tj__d2o9me___1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	
d1n3tk__d1ws3b2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1n3tl__d3pk4a1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1n3to__d3qn0a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	queuosine biosynthetic process [GO:0008616]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d1n3ua__d1v8xa___1	Metazoa		Chordata	Actinobacteria	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	heme oxidation [GO:0006788]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]		enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d1n3ua__d3hlxa1__1	Metazoa		Chordata	Proteobacteria	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	pyrroloquinoline-quinone synthase activity [GO:0033732]; pyrroloquinoline quinone biosynthetic process [GO:0018189]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	pyrroloquinoline quinone biosynthetic process [GO:0018189]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]		enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	pyrroloquinoline-quinone synthase activity [GO:0033732]
d1n3ub__d1ubba___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1n3ub__d2qcxb1__1	Metazoa		Chordata	Firmicutes	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cytosol [GO:0005829]; thiaminase activity [GO:0050334]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cytosol [GO:0005829]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	thiaminase activity [GO:0050334]
d1n3wa__d5elva1__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1n40a__d3r9ca___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]		carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1n42a__d1hakb___1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]
d1n43b__d4bj8a___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1n44a__d1m9ia1__1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; actin filament binding [GO:0051015]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; cholesterol binding [GO:0015485]; chondroitin sulfate binding [GO:0035374]; GTP binding [GO:0005525]; ligand-gated ion channel activity [GO:0015276]; lipid binding [GO:0008289]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; apoptotic signaling pathway [GO:0097190]; growth plate cartilage chondrocyte differentiation [GO:0003418]; ion transmembrane transport [GO:0034220]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; plasma membrane repair [GO:0001778]; protein homooligomerization [GO:0051260]; regulation of muscle contraction [GO:0006937]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	apoptotic signaling pathway [GO:0097190]; growth plate cartilage chondrocyte differentiation [GO:0003418]; ion transmembrane transport [GO:0034220]; mitochondrial calcium ion homeostasis [GO:0051560]; negative regulation of sequestering of calcium ion [GO:0051283]; plasma membrane repair [GO:0001778]; protein homooligomerization [GO:0051260]; regulation of muscle contraction [GO:0006937]	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; melanosome [GO:0042470]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]	actin filament binding [GO:0051015]; calcium channel activity [GO:0005262]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cholesterol binding [GO:0015485]; chondroitin sulfate binding [GO:0035374]; GTP binding [GO:0005525]; ligand-gated ion channel activity [GO:0015276]; lipid binding [GO:0008289]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]
d1n47b__d1gicb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1n47c__d1v6lc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1n48a1_d4nlga2__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d1n49a__d1pple___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1n4ha__d4e4ka___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]; activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]	androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]	activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]
d1n4pb__d1s63b___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]; protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]; protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]
d1n4pc__d2r2la___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1n4pd__d1o79b2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1n4ph__d3sqcc2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1n4pl__d1h3aa2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1n4qf__d5ikha1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	cytoplasm [GO:0005737]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d1n4qj__d1o6rb2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1n4rd__d1o6rc2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]; actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	hopanoid biosynthetic process [GO:0019746]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1n4rf__d3lz9a1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]; actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d1n4sf__d4m76a1__1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d1n4sh__d2ongb1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]		CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]		CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d1n4sj__d2xqwa1__1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d1n4va2_d1gala2__1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	extracellular region [GO:0005576]; flavin adenine dinucleotide binding [GO:0050660]; glucose oxidase activity [GO:0046562]	cholesterol metabolic process [GO:0008203]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]	flavin adenine dinucleotide binding [GO:0050660]; glucose oxidase activity [GO:0046562]
d1n4xh1_d1yedb1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1n4xh1_d4zs6d2__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]	
d1n4xl1_d4ydkl2__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]	structural molecule activity [GO:0005198]
d1n4xm1_d3qpxl2__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		antigen binding [GO:0003823]	
d1n50b2_d1gq1b2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1n51a1_d1chmb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	creatinase activity [GO:0016980]			cytosol [GO:0005829]		aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	creatinase activity [GO:0016980]
d1n54a2_d1t06a___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]		7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]		mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]	
d1n54b__d2vodb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; nuclear chromosome, telomeric region [GO:0000784]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049]; histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]	cytoplasm [GO:0005737]; nuclear chromosome, telomeric region [GO:0000784]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]	mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049]
d1n56a1_d1k1qb1__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d1n59a1_d4yjzl2__1	Metazoa		Chordata	Negarnaviricota	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	host cell surface receptor binding [GO:0046789]
d1n59a2_d4fqxb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1n59b__d2dtqb4__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1n59b__d2fx9l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	structural molecule activity [GO:0005198]
d1n59c1_d4wi5b2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1n59d__d1oauj___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1n5ag1_d5f9ol1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1n5aj2_d3qiub1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1n5bd__d1ry9b___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; pathogenesis [GO:0009405]; regulation of protein secretion [GO:0050708]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]; regulation of protein secretion [GO:0050708]	pathogenesis [GO:0009405]	cytoplasm [GO:0005737]			
d1n5bd__d3epub___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; pathogenesis [GO:0009405]; regulation of protein secretion [GO:0050708]	cytoplasm [GO:0005737]; regulation of protein secretion [GO:0050708]	pathogenesis [GO:0009405]; regulation of protein secretion [GO:0050708]	regulation of protein secretion [GO:0050708]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]		
d1n5qb__d3znj4___1			Actinobacteria	Actinobacteria	monooxygenase activity [GO:0004497]	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]		beta-ketoadipate pathway [GO:0042952]			monooxygenase activity [GO:0004497]	muconolactone delta-isomerase activity [GO:0016159]
d1n5sb__d3znj1___1			Actinobacteria	Actinobacteria	monooxygenase activity [GO:0004497]	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]		beta-ketoadipate pathway [GO:0042952]			monooxygenase activity [GO:0004497]	muconolactone delta-isomerase activity [GO:0016159]
d1n5tb__d4lbha___1			Actinobacteria	Proteobacteria	monooxygenase activity [GO:0004497]						monooxygenase activity [GO:0004497]	
d1n5wc1_d2w3rg4__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1n5wf1_d3ns1k2__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1n5wf2_d1ahzb2__1		Fungi	Proteobacteria	Ascomycota	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]		methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1n5xb4_d3ns1b2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1n5yl1_d5esvd2__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1n60a1_d4us9a2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1n60b1_d3nvyl1__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1n60c1_d3amzb4__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1n60d1_d1ffvd1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1n60d1_d2w3se2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1n60d2_d1kf6b2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1n60e1_d3rcal1__1			Proteobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	
d1n60f2_d3nvzk1__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1n60f2_d5fxpa1__1			Proteobacteria	Actinobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1n61a1_d2w3rg2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1n61a1_d3amzb2__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1n61a2_d1xlqb___1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1n61d2_d5bysb1__1			Proteobacteria	Firmicutes	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]
d1n61f1_d3nrzk2__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1n61f2_d2vaoa2__1		Fungi	Proteobacteria	Ascomycota	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]		methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1n62b2_d3rcac2__1			Proteobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	
d1n62c2_d1jrpg4__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1n62d2_d3euba1__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1n62e1_d2w3rd1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1n62f1_d1zxif1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1n63c1_d1sb3b1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]
d1n63d2_d2b76n2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1n64l1_d2pcpb2__1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d1n64l1_d5m94d___1				Firmicutes	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; metal ion transmembrane transporter activity [GO:0046873]; symporter activity [GO:0015293]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metal ion transmembrane transporter activity [GO:0046873]; symporter activity [GO:0015293]
d1n68a2_d2qt6a3__1		Fungi	Proteobacteria	Basidiomycota	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1n6ba1_d3iw0a___1	Metazoa		Chordata	Actinobacteria	endoplasmic reticulum membrane [GO:0005789]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; steroid hydroxylase activity [GO:0008395]; cholesterol catabolic process [GO:0006707]; growth of symbiont in host [GO:0044117]; pathogenesis [GO:0009405]		cholesterol catabolic process [GO:0006707]; growth of symbiont in host [GO:0044117]; pathogenesis [GO:0009405]	endoplasmic reticulum membrane [GO:0005789]		aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; steroid hydroxylase activity [GO:0008395]
d1n6eg1_d2d90a1__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]; carnitine transport [GO:0015879]; in utero embryonic development [GO:0001701]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; protein localization to plasma membrane [GO:0072659]; regulation of anion transport [GO:0044070]	proteolysis [GO:0006508]	carnitine transport [GO:0015879]; in utero embryonic development [GO:0001701]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; protein localization to plasma membrane [GO:0072659]; regulation of anion transport [GO:0044070]	cytoplasm [GO:0005737]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]	serine-type peptidase activity [GO:0008236]	PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]
d1n6ff1_d5vwca1__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; myelin sheath abaxonal region [GO:0035748]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Scrib-APC-beta-catenin complex [GO:0034750]; synapse [GO:0045202]; cadherin binding [GO:0045296]; activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; auditory receptor cell stereocilium organization [GO:0060088]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; post-anal tail morphogenesis [GO:0036342]; protein localization to adherens junction [GO:0071896]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; wound healing [GO:0042060]	proteolysis [GO:0006508]	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; auditory receptor cell stereocilium organization [GO:0060088]; cell-cell adhesion [GO:0098609]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; post-anal tail morphogenesis [GO:0036342]; protein localization to adherens junction [GO:0071896]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; wound healing [GO:0042060]	cytoplasm [GO:0005737]	basolateral plasma membrane [GO:0016323]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; myelin sheath abaxonal region [GO:0035748]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Scrib-APC-beta-catenin complex [GO:0034750]; synapse [GO:0045202]	serine-type peptidase activity [GO:0008236]	cadherin binding [GO:0045296]
d1n6jb__d3kovj___1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein phosphatase inhibitor activity [GO:0004864]; cell surface receptor signaling pathway [GO:0007166]; DNA replication-independent nucleosome assembly [GO:0006336]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	cell surface receptor signaling pathway [GO:0007166]; DNA replication-independent nucleosome assembly [GO:0006336]	apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	aggresome [GO:0016235]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	protein phosphatase inhibitor activity [GO:0004864]	activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1n6ka__d2cl0x___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; anchored component of synaptic vesicle membrane [GO:0098993]; axon [GO:0030424]; axon terminus [GO:0043679]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic side of early endosome membrane [GO:0098559]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic early endosome [GO:0098842]; ruffle [GO:0001726]; somatodendritic compartment [GO:0036477]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; amyloid-beta clearance by transcytosis [GO:0150093]; blood coagulation [GO:0007596]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of exocytosis [GO:0045921]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286]; regulation of autophagosome assembly [GO:2000785]; regulation of endosome size [GO:0051036]; regulation of filopodium assembly [GO:0051489]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465]; viral RNA genome replication [GO:0039694]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid-beta clearance by transcytosis [GO:0150093]; blood coagulation [GO:0007596]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of exocytosis [GO:0045921]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286]; regulation of autophagosome assembly [GO:2000785]; regulation of endosome size [GO:0051036]; regulation of filopodium assembly [GO:0051489]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465]; viral RNA genome replication [GO:0039694]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	actin cytoskeleton [GO:0015629]; anchored component of synaptic vesicle membrane [GO:0098993]; axon [GO:0030424]; axon terminus [GO:0043679]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic side of early endosome membrane [GO:0098559]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic early endosome [GO:0098842]; ruffle [GO:0001726]; somatodendritic compartment [GO:0036477]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1n6na__d5ciwa___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; anchored component of synaptic vesicle membrane [GO:0098993]; axon [GO:0030424]; axon terminus [GO:0043679]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic side of early endosome membrane [GO:0098559]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic early endosome [GO:0098842]; ruffle [GO:0001726]; somatodendritic compartment [GO:0036477]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; amyloid-beta clearance by transcytosis [GO:0150093]; blood coagulation [GO:0007596]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of exocytosis [GO:0045921]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286]; regulation of autophagosome assembly [GO:2000785]; regulation of endosome size [GO:0051036]; regulation of filopodium assembly [GO:0051489]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465]; viral RNA genome replication [GO:0039694]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	amyloid-beta clearance by transcytosis [GO:0150093]; blood coagulation [GO:0007596]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of exocytosis [GO:0045921]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286]; regulation of autophagosome assembly [GO:2000785]; regulation of endosome size [GO:0051036]; regulation of filopodium assembly [GO:0051489]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465]; viral RNA genome replication [GO:0039694]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	actin cytoskeleton [GO:0015629]; anchored component of synaptic vesicle membrane [GO:0098993]; axon [GO:0030424]; axon terminus [GO:0043679]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic side of early endosome membrane [GO:0098559]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic early endosome [GO:0098842]; ruffle [GO:0001726]; somatodendritic compartment [GO:0036477]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1n6qa1_d1wsfb___1				Proteobacteria	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1n6qh2_d1t7va1__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]
d1n6ql2_d4m61a2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d1n6ua1_d6b2ad___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	integral component of plasma membrane [GO:0005887]; inorganic anion transmembrane transporter activity [GO:0015103]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]	cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]	inorganic anion transmembrane transporter activity [GO:0015103]
d1n6va1_d3b83f1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]		cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]	
d1n6ya__d2v6na___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	digestion [GO:0007586]; proteolysis [GO:0006508]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1n6ya__d3e3ta___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1n70a2_d3n2jl___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1n73c1_d2j3gd___1	Metazoa	Metazoa	Chordata	Chordata	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	fibrinogen complex [GO:0005577]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1n73e1_d1fzef1__1	Metazoa	Metazoa	Chordata	Chordata	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	fibrinogen complex [GO:0005577]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d1n73e1_d2j3od___1	Metazoa	Metazoa	Chordata	Chordata	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	fibrinogen complex [GO:0005577]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1n77a2_d1d2rb___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	glutamyl-tRNA aminoacylation [GO:0006424]	tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d1n78a1_d2cfoa2__1			Deinococcus-Thermus	Cyanobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	glutamyl-tRNA aminoacylation [GO:0006424]	glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1n7ea__d3stjh2__1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; glucocorticoid receptor binding [GO:0035259]; receptor signaling complex adaptor activity [GO:0030159]; signaling receptor binding [GO:0005102]; dendrite development [GO:0016358]; nervous system development [GO:0007399]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection arborization [GO:0150012]; protein transport [GO:0015031]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	dendrite development [GO:0016358]; nervous system development [GO:0007399]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection arborization [GO:0150012]; protein transport [GO:0015031]	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]	glucocorticoid receptor binding [GO:0035259]; receptor signaling complex adaptor activity [GO:0030159]; signaling receptor binding [GO:0005102]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]
d1n7fa__d3ps4a1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; glucocorticoid receptor binding [GO:0035259]; receptor signaling complex adaptor activity [GO:0030159]; signaling receptor binding [GO:0005102]; dendrite development [GO:0016358]; nervous system development [GO:0007399]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection arborization [GO:0150012]; protein transport [GO:0015031]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein serine/threonine kinase activity [GO:0004674]; brain development [GO:0007420]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]	dendrite development [GO:0016358]; nervous system development [GO:0007399]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection arborization [GO:0150012]; protein transport [GO:0015031]	brain development [GO:0007420]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]	glucocorticoid receptor binding [GO:0035259]; receptor signaling complex adaptor activity [GO:0030159]; signaling receptor binding [GO:0005102]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein serine/threonine kinase activity [GO:0004674]
d1n7fb__d1w9qb1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; glucocorticoid receptor binding [GO:0035259]; receptor signaling complex adaptor activity [GO:0030159]; signaling receptor binding [GO:0005102]; dendrite development [GO:0016358]; nervous system development [GO:0007399]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection arborization [GO:0150012]; protein transport [GO:0015031]	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]; actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	dendrite development [GO:0016358]; nervous system development [GO:0007399]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection arborization [GO:0150012]; protein transport [GO:0015031]	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]	glucocorticoid receptor binding [GO:0035259]; receptor signaling complex adaptor activity [GO:0030159]; signaling receptor binding [GO:0005102]	cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]
d1n7ia__d2pxca___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	phenylethanolamine N-methyltransferase activity [GO:0004603]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1n7jb__d2br5a___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		phenylethanolamine N-methyltransferase activity [GO:0004603]	methyltransferase activity [GO:0008168]
d1n7ka__d2r91a___1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]; protein tetramerization [GO:0051262]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]; protein tetramerization [GO:0051262]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		deoxyribose-phosphate aldolase activity [GO:0004139]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]
d1n7mh1_d4jo1l1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1n7mh2_d1hq4c2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1n7ml2_d1i8lb2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1n7pa3_d3t0bb5__1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	cell wall [GO:0005618]; extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1n7qa1_d3ew4b1__1			Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		cell wall [GO:0005618]; extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	
d1n7qa3_d3bvta2__1		Metazoa	Firmicutes	Arthropoda	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	cell wall [GO:0005618]; extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1n7ra1_d3evlb1__1			Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		cell wall [GO:0005618]; extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	
d1n7ra3_d1jyvb4__1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	cell wall [GO:0005618]; extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1n7ta1_d5tnza2__1	Metazoa	Metazoa	Chordata	Chordata	basal plasma membrane [GO:0009925]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; hemidesmosome [GO:0030056]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ErbB-2 class receptor binding [GO:0005176]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]; basal protein localization [GO:0045175]; cell adhesion [GO:0007155]; cellular response to tumor necrosis factor [GO:0071356]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165]	CD40 receptor complex [GO:0035631]; chromatin [GO:0000785]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial intermembrane space [GO:0005758]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; serine-type endopeptidase complex [GO:1905370]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; unfolded protein binding [GO:0051082]; adult walking behavior [GO:0007628]; aging [GO:0007568]; cellular protein catabolic process [GO:0044257]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to interferon-beta [GO:0035458]; cellular response to oxidative stress [GO:0034599]; cellular response to retinoic acid [GO:0071300]; ceramide metabolic process [GO:0006672]; execution phase of apoptosis [GO:0097194]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitochondrion organization [GO:0007005]; negative regulation of cell cycle [GO:0045786]; negative regulation of mitophagy in response to mitochondrial depolarization [GO:1904924]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; neuron development [GO:0048666]; pentacyclic triterpenoid metabolic process [GO:0019742]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein autoprocessing [GO:0016540]; protein homotrimerization [GO:0070207]; proteolysis [GO:0006508]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of multicellular organism growth [GO:0040014]; response to herbicide [GO:0009635]	basal protein localization [GO:0045175]; cell adhesion [GO:0007155]; cellular response to tumor necrosis factor [GO:0071356]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165]	adult walking behavior [GO:0007628]; aging [GO:0007568]; cellular protein catabolic process [GO:0044257]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to interferon-beta [GO:0035458]; cellular response to oxidative stress [GO:0034599]; cellular response to retinoic acid [GO:0071300]; ceramide metabolic process [GO:0006672]; execution phase of apoptosis [GO:0097194]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitochondrion organization [GO:0007005]; negative regulation of cell cycle [GO:0045786]; negative regulation of mitophagy in response to mitochondrial depolarization [GO:1904924]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; neuron development [GO:0048666]; pentacyclic triterpenoid metabolic process [GO:0019742]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein autoprocessing [GO:0016540]; protein homotrimerization [GO:0070207]; proteolysis [GO:0006508]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of multicellular organism growth [GO:0040014]; response to herbicide [GO:0009635]	basal plasma membrane [GO:0009925]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; hemidesmosome [GO:0030056]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	CD40 receptor complex [GO:0035631]; chromatin [GO:0000785]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial intermembrane space [GO:0005758]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; serine-type endopeptidase complex [GO:1905370]	ErbB-2 class receptor binding [GO:0005176]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; unfolded protein binding [GO:0051082]
d1n82b__d1jaea2__1		Metazoa	Firmicutes	Arthropoda	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	xylan catabolic process [GO:0045493]	carbohydrate catabolic process [GO:0016052]			endo-1,4-beta-xylanase activity [GO:0031176]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1n84a__d1h43a___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d1n86e1_d1fzgf1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d1n86f1_d2j3gb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1n89a__d1bipa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cell wall [GO:0005618]; extracellular region [GO:0005576]; lipid binding [GO:0008289]; cell wall organization [GO:0071555]; lipid transport [GO:0006869]	extracellular region [GO:0005576]; alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]	cell wall organization [GO:0071555]; lipid transport [GO:0006869]		cell wall [GO:0005618]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	lipid binding [GO:0008289]	alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]
d1n8ee1_d4nyta___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1n8ef1_d1lt9e1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d1n8ef1_d2j2pf___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1n8jb__d1tp9b___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]	thioredoxin peroxidase activity [GO:0008379]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1n8jc__d1xxua___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; response to nitrosative stress [GO:0051409]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; response to nitrosative stress [GO:0051409]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	thioredoxin peroxidase activity [GO:0008379]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]
d1n8je__d5el8a1__1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vacuole [GO:0005773]; copper ion binding [GO:0005507]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; voltage-gated ion channel activity [GO:0005244]; cellular response to hydrogen peroxide [GO:0070301]; defense response [GO:0006952]; positive regulation of salicylic acid mediated signaling pathway [GO:0080151]; protein glutathionylation [GO:0010731]; regulation of ion transmembrane transport [GO:0034765]; regulation of symbiosis, encompassing mutualism through parasitism [GO:0043903]; response to jasmonic acid [GO:0009753]; response to ozone [GO:0010193]; response to symbiotic fungus [GO:0009610]; response to zinc ion [GO:0010043]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cellular response to hydrogen peroxide [GO:0070301]; defense response [GO:0006952]; positive regulation of salicylic acid mediated signaling pathway [GO:0080151]; protein glutathionylation [GO:0010731]; regulation of ion transmembrane transport [GO:0034765]; regulation of symbiosis, encompassing mutualism through parasitism [GO:0043903]; response to jasmonic acid [GO:0009753]; response to ozone [GO:0010193]; response to symbiotic fungus [GO:0009610]; response to zinc ion [GO:0010043]	cell [GO:0005623]; cytosol [GO:0005829]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vacuole [GO:0005773]	thioredoxin peroxidase activity [GO:0008379]	copper ion binding [GO:0005507]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; voltage-gated ion channel activity [GO:0005244]
d1n8jg__d4acsc1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	thioredoxin peroxidase activity [GO:0008379]	glutathione transferase activity [GO:0004364]
d1n8jh__d2eioc___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	thioredoxin peroxidase activity [GO:0008379]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1n8ji__d3a2vb___1			Proteobacteria	Crenarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]	thioredoxin peroxidase activity [GO:0008379]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1n8jj__d2vcvp1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	thioredoxin peroxidase activity [GO:0008379]	glutathione transferase activity [GO:0004364]
d1n8jm__d4od7b1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; periplasmic space [GO:0042597]	thioredoxin peroxidase activity [GO:0008379]	protein disulfide oxidoreductase activity [GO:0015035]
d1n8jo__d2v2ga___1		Metazoa	Proteobacteria	Annelida	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]	thioredoxin peroxidase activity [GO:0008379]	peroxiredoxin activity [GO:0051920]
d1n8jp__d1gnea2__1		Metazoa	Proteobacteria	Platyhelminthes	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cytosol [GO:0005829]		thioredoxin peroxidase activity [GO:0008379]	glutathione transferase activity [GO:0004364]
d1n8jq__d2flsa1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; dendrite [GO:0030425]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 2 iron, 2 sulfur cluster binding [GO:0051537]; arsenate reductase (glutaredoxin) activity [GO:0008794]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; metal ion binding [GO:0046872]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; aging [GO:0007568]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; cellular response to superoxide [GO:0071451]; DNA protection [GO:0042262]; glutathione metabolic process [GO:0006749]; regulation of signal transduction [GO:0009966]; regulation of transcription, DNA-templated [GO:0006355]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to redox state [GO:0051775]; response to temperature stimulus [GO:0009266]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	aging [GO:0007568]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; cellular response to superoxide [GO:0071451]; DNA protection [GO:0042262]; glutathione metabolic process [GO:0006749]; regulation of signal transduction [GO:0009966]; regulation of transcription, DNA-templated [GO:0006355]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to redox state [GO:0051775]; response to temperature stimulus [GO:0009266]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; dendrite [GO:0030425]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	thioredoxin peroxidase activity [GO:0008379]	2 iron, 2 sulfur cluster binding [GO:0051537]; arsenate reductase (glutaredoxin) activity [GO:0008794]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; metal ion binding [GO:0046872]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d1n8ka2_d4r1nd1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]
d1n8na__d4hgnb___1			Proteobacteria	Bacteroidetes	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]	outer membrane-bounded periplasmic space [GO:0030288]		acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d1n8pb__d2dglf___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; carbon-sulfur lyase activity [GO:0016846]; cystathionine gamma-lyase activity [GO:0004123]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; L-cystine L-cysteine-lyase (deaminating) [GO:0044540]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process via cystathionine [GO:0019343]; transsulfuration [GO:0019346]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process via cystathionine [GO:0019343]; transsulfuration [GO:0019346]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	carbon-sulfur lyase activity [GO:0016846]; cystathionine gamma-lyase activity [GO:0004123]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; L-cystine L-cysteine-lyase (deaminating) [GO:0044540]; pyridoxal phosphate binding [GO:0030170]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]
d1n8rd__d1dara1__1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	translation [GO:0006412]		ribosome [GO:0005840]	cytoplasm [GO:0005737]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1n8rg2_d1vqke1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1n8rh__d3ccuf1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1n8ta__d2cxta___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d1n8tb__d2xblc___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]
d1n8va__d2gvsa___1	Metazoa	Metazoa	Arthropoda	Arthropoda								
d1n8za1_d2vllb2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1n8zb2_d3mcka1__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]	
d1n97a__d3n9zb___1		Metazoa	Deinococcus-Thermus	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]		C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]
d1n97b__d2uwhd___1			Deinococcus-Thermus	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d1n97b__d3n9ya___1		Metazoa	Deinococcus-Thermus	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]		C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]
d1n9ca__d1nira1__1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1n9da__d1ik0a1__1		Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]
d1n9ec2_d2cfda3__1	Fungi		Ascomycota	Actinobacteria	copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; amine metabolic process [GO:0009308]; cellular response to inorganic substance [GO:0071241]; oxidation-reduction process [GO:0055114]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; cellular response to inorganic substance [GO:0071241]; oxidation-reduction process [GO:0055114]	amine metabolic process [GO:0009308]			copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d1n9ga2_d1hdca___1	Fungi		Ascomycota	Actinobacteria	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; C21-steroid hormone metabolic process [GO:0008207]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	C21-steroid hormone metabolic process [GO:0008207]	mitochondrion [GO:0005739]		trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]
d1n9gf2_d5i9ma___1	Fungi		Ascomycota	Proteobacteria	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]	mitochondrion [GO:0005739]		trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d1n9ha__d5x2sk___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1n9ia__d3qjba___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1n9kb__d3hycc___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]	outer membrane-bounded periplasmic space [GO:0030288]		acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1n9mb__d2mf6a1__1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1n9mb__d4bboa___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1n9mc__d4ggzb___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1n9na__d1jnua___1	Viridiplantae	Viridiplantae	Chlorophyta	Streptophyta	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; photoreceptor activity [GO:0009881]; protein serine/threonine kinase activity [GO:0004674]; protein phosphorylation [GO:0006468]; protein-chromophore linkage [GO:0018298]; response to stimulus [GO:0050896]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	protein-chromophore linkage [GO:0018298]; protein phosphorylation [GO:0006468]; response to stimulus [GO:0050896]	detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; photoreceptor activity [GO:0009881]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]
d1n9oa__d3h82b1__1	Viridiplantae	Metazoa	Chlorophyta	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; photoreceptor activity [GO:0009881]; protein serine/threonine kinase activity [GO:0004674]; protein phosphorylation [GO:0006468]; protein-chromophore linkage [GO:0018298]; response to stimulus [GO:0050896]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]	protein-chromophore linkage [GO:0018298]; protein phosphorylation [GO:0006468]; response to stimulus [GO:0050896]	angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; photoreceptor activity [GO:0009881]; protein serine/threonine kinase activity [GO:0004674]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d1n9rc__d1i81b___1	Fungi		Ascomycota	Euryarchaeota	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	mRNA splicing, via spliceosome [GO:0000398]	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	small nucleolar ribonucleoprotein complex [GO:0005732]	poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]	
d1n9rd__d1n9sc___1	Fungi	Fungi	Ascomycota	Ascomycota	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]	poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]
d1n9sb__d1m8vf___1	Fungi		Ascomycota	Euryarchaeota	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]	
d1n9sh__d1h64y___1	Fungi		Ascomycota	Euryarchaeota	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]	
d1n9sm__d1d3bj___1	Fungi	Metazoa	Ascomycota	Chordata	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]; enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]; histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]	mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	histone mRNA metabolic process [GO:0008334]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; termination of RNA polymerase II transcription [GO:0006369]	catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; cytosol [GO:0005829]; methylosome [GO:0034709]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; small nuclear ribonucleoprotein complex [GO:0030532]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]; U7 snRNP [GO:0005683]	poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]	enzyme binding [GO:0019899]; histone pre-mRNA DCP binding [GO:0071208]; RNA binding [GO:0003723]; telomerase RNA binding [GO:0070034]; U1 snRNP binding [GO:1990446]; U7 snRNA binding [GO:0071209]
d1n9xa__d4avda___1	Metazoa	Metazoa	Chordata	Nemertea (ribbon worms)	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1n9za__d1zopa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]
d1na1.1_d1rud1___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1na1a__d4y5zt___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1na5a1_d1ao3a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d1na6b1_d1wida___1		Viridiplantae	Proteobacteria	Streptophyta	DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; ethylene-activated signaling pathway [GO:0009873]; lateral root development [GO:0048527]; leaf development [GO:0048366]; negative regulation of flower development [GO:0009910]; negative regulation of transcription, DNA-templated [GO:0045892]; response to brassinosteroid [GO:0009741]	DNA restriction-modification system [GO:0009307]	ethylene-activated signaling pathway [GO:0009873]; lateral root development [GO:0048527]; leaf development [GO:0048366]; negative regulation of flower development [GO:0009910]; negative regulation of transcription, DNA-templated [GO:0045892]; response to brassinosteroid [GO:0009741]		nucleus [GO:0005634]	DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1na8a1_d1gyva___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]; collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]
d1na8b__d1e42b1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	AP-2 adaptor complex [GO:0030122]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]; clathrin binding [GO:0030276]; protein-containing complex binding [GO:0044877]; signal sequence binding [GO:0005048]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; coronary vasculature development [GO:0060976]; ephrin receptor signaling pathway [GO:0048013]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; membrane organization [GO:0061024]; negative regulation of neuron death [GO:1901215]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein localization to membrane [GO:1905477]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; regulation of defense response to virus by virus [GO:0050690]; synaptic vesicle endocytosis [GO:0048488]; ventricular septum development [GO:0003281]; vesicle-mediated transport [GO:0016192]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; coronary vasculature development [GO:0060976]; ephrin receptor signaling pathway [GO:0048013]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; membrane organization [GO:0061024]; negative regulation of neuron death [GO:1901215]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein localization to membrane [GO:1905477]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; regulation of defense response to virus by virus [GO:0050690]; synaptic vesicle endocytosis [GO:0048488]; ventricular septum development [GO:0003281]; vesicle-mediated transport [GO:0016192]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	AP-2 adaptor complex [GO:0030122]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	clathrin binding [GO:0030276]; protein-containing complex binding [GO:0044877]; signal sequence binding [GO:0005048]
d1naea__d1w9wa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group [GO:0052861]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group [GO:0052861]
d1naha__d3a9wa___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]; carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]
d1naia__d2cdhi1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]; carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1nakh1_d1kemh2__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1nakh2_d1xede1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; polymeric immunoglobulin receptor activity [GO:0001792]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc receptor signaling pathway [GO:0038093]; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [GO:0002415]; neutrophil degranulation [GO:0043312]; receptor clustering [GO:0043113]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc receptor signaling pathway [GO:0038093]; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [GO:0002415]; neutrophil degranulation [GO:0043312]; receptor clustering [GO:0043113]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	polymeric immunoglobulin receptor activity [GO:0001792]
d1nakh2_d3b3ib2__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1naki1_d1bbjh1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1naki2_d3juya1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	
d1nakl2_d6ehyb1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	
d1nakm2_d4lvhi1__1				Negarnaviricota	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	host cell surface receptor binding [GO:0046789]
d1nal3__d5kzec___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	N-acetylneuraminate lyase activity [GO:0008747]
d1nal4__d3lcwd___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d1namb__d1jpgb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1namh1_d2ig2l2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1nanh1_d5mwnd1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1nanl1_d1adqh1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1nanp__d4gmsm1__1	Metazoa		Chordata	Negarnaviricota	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d1napb__d1o7yd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; tertiary granule lumen [GO:1904724]; chemokine activity [GO:0008009]; glucose transmembrane transporter activity [GO:0005355]; growth factor activity [GO:0008083]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; defense response to bacterium [GO:0042742]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose transmembrane transport [GO:1904659]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of cell division [GO:0051781]	cell [GO:0005623]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cAMP-dependent protein kinase regulator activity [GO:0008603]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]; signaling receptor binding [GO:0005102]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood circulation [GO:0008015]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular response to heat [GO:0034605]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; endothelial cell activation [GO:0042118]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; muscle organ development [GO:0007517]; negative regulation of angiogenesis [GO:0016525]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast fusion [GO:1901740]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of endothelial tube morphogenesis [GO:1901509]; regulation of T cell chemotaxis [GO:0010819]; response to auditory stimulus [GO:0010996]; response to cold [GO:0009409]; response to gamma radiation [GO:0010332]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell chemotaxis [GO:0010818]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; defense response to bacterium [GO:0042742]; glucose transmembrane transport [GO:1904659]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of cell division [GO:0051781]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood circulation [GO:0008015]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular response to heat [GO:0034605]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; endothelial cell activation [GO:0042118]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; muscle organ development [GO:0007517]; negative regulation of angiogenesis [GO:0016525]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast fusion [GO:1901740]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of endothelial tube morphogenesis [GO:1901509]; regulation of T cell chemotaxis [GO:0010819]; response to auditory stimulus [GO:0010996]; response to cold [GO:0009409]; response to gamma radiation [GO:0010332]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell chemotaxis [GO:0010818]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	chemokine activity [GO:0008009]; glucose transmembrane transporter activity [GO:0005355]; growth factor activity [GO:0008083]	cAMP-dependent protein kinase regulator activity [GO:0008603]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]; signaling receptor binding [GO:0005102]
d1naqb__d1pila___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; metal ion binding [GO:0046872]; protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	cytosol [GO:0005829]; ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; small molecule binding [GO:0036094]; regulation of catalytic activity [GO:0050790]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of nitrogen utilization [GO:0006808]	protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	regulation of catalytic activity [GO:0050790]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of nitrogen utilization [GO:0006808]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	copper ion binding [GO:0005507]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; small molecule binding [GO:0036094]
d1nara__d1w3la___1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]
d1nasa__d2aefa1__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; protein homodimerization activity [GO:0042803]; sepiapterin reductase activity [GO:0004757]; cell morphogenesis involved in neuron differentiation [GO:0048667]; dopamine metabolic process [GO:0042417]; L-phenylalanine metabolic process [GO:0006558]; nitric oxide biosynthetic process [GO:0006809]; norepinephrine metabolic process [GO:0042415]; pteridine metabolic process [GO:0019889]; regulation of multicellular organism growth [GO:0040014]; response to organic substance [GO:0010033]; serotonin metabolic process [GO:0042428]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrobiopterin metabolic process [GO:0046146]; voluntary musculoskeletal movement [GO:0050882]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	cell morphogenesis involved in neuron differentiation [GO:0048667]; dopamine metabolic process [GO:0042417]; L-phenylalanine metabolic process [GO:0006558]; nitric oxide biosynthetic process [GO:0006809]; norepinephrine metabolic process [GO:0042415]; pteridine metabolic process [GO:0019889]; regulation of multicellular organism growth [GO:0040014]; response to organic substance [GO:0010033]; serotonin metabolic process [GO:0042428]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrobiopterin metabolic process [GO:0046146]; voluntary musculoskeletal movement [GO:0050882]	potassium ion transport [GO:0006813]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	protein homodimerization activity [GO:0042803]; sepiapterin reductase activity [GO:0004757]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1naxa__d5apkb___1	Metazoa	Metazoa	Chordata	Chordata	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; thyroid hormone binding [GO:0070324]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; female courtship behavior [GO:0008050]; hormone-mediated signaling pathway [GO:0009755]; multicellular organism development [GO:0007275]; negative regulation of eye photoreceptor cell development [GO:0042480]; negative regulation of female receptivity [GO:0007621]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of heart contraction [GO:0008016]; response to lipid [GO:0033993]; retinal cone cell apoptotic process [GO:0097474]; retinal cone cell development [GO:0046549]; sensory perception of sound [GO:0007605]; thyroid gland development [GO:0030878]; thyroid hormone mediated signaling pathway [GO:0002154]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]; type I pneumocyte differentiation [GO:0060509]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; female courtship behavior [GO:0008050]; hormone-mediated signaling pathway [GO:0009755]; multicellular organism development [GO:0007275]; negative regulation of eye photoreceptor cell development [GO:0042480]; negative regulation of female receptivity [GO:0007621]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of heart contraction [GO:0008016]; response to lipid [GO:0033993]; retinal cone cell apoptotic process [GO:0097474]; retinal cone cell development [GO:0046549]; sensory perception of sound [GO:0007605]; thyroid gland development [GO:0030878]; thyroid hormone mediated signaling pathway [GO:0002154]; transcription, DNA-templated [GO:0006351]; transcription initiation from RNA polymerase II promoter [GO:0006367]; type I pneumocyte differentiation [GO:0060509]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; thyroid hormone binding [GO:0070324]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d1nb3.2_d1gmyb___1	Metazoa	Metazoa	Chordata	Chordata	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]	cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]
d1nb3.3_d1cv8a___1	Metazoa		Chordata	Firmicutes	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]; pathogenesis [GO:0009405]	cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	pathogenesis [GO:0009405]	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]	cysteine-type peptidase activity [GO:0008234]
d1nb3.3_d4axla___1	Metazoa	Metazoa	Chordata	Chordata	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; histone binding [GO:0042393]; proteoglycan binding [GO:0043394]; serpin family protein binding [GO:0097655]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; macrophage apoptotic process [GO:0071888]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; macrophage apoptotic process [GO:0071888]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; histone binding [GO:0042393]; proteoglycan binding [GO:0043394]; serpin family protein binding [GO:0097655]
d1nb3.4_d3f75a___1	Metazoa		Chordata	Apicomplexa	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	integral component of membrane [GO:0016021]; cysteine-type peptidase activity [GO:0008234]	cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	integral component of membrane [GO:0016021]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]	cysteine-type peptidase activity [GO:0008234]
d1nb3i__d2w9pi___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	cysteine-type endopeptidase inhibitor activity [GO:0004869]	cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]		cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]	cysteine-type endopeptidase inhibitor activity [GO:0004869]
d1nb3l__d4n6nb1__1	Metazoa	Metazoa	Chordata	Chordata	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; perinuclear region of cytoplasm [GO:0048471]; cysteine-type endopeptidase activity [GO:0004197]; peptidase activity [GO:0008233]; tau protein binding [GO:0048156]; activation of cysteine-type endopeptidase activity [GO:0097202]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; associative learning [GO:0008306]; cellular response to amyloid-beta [GO:1904646]; cellular response to calcium ion [GO:0071277]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; dendritic spine organization [GO:0097061]; memory [GO:0007613]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of gene expression [GO:0010629]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; receptor catabolic process [GO:0032801]; renal system process [GO:0003014]; response to acidic pH [GO:0010447]; self proteolysis [GO:0097264]; toll-like receptor signaling pathway [GO:0002224]; vacuolar protein processing [GO:0006624]; vitamin D metabolic process [GO:0042359]	cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	activation of cysteine-type endopeptidase activity [GO:0097202]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; associative learning [GO:0008306]; cellular response to amyloid-beta [GO:1904646]; cellular response to calcium ion [GO:0071277]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; dendritic spine organization [GO:0097061]; memory [GO:0007613]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of gene expression [GO:0010629]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; receptor catabolic process [GO:0032801]; renal system process [GO:0003014]; response to acidic pH [GO:0010447]; self proteolysis [GO:0097264]; toll-like receptor signaling pathway [GO:0002224]; vacuolar protein processing [GO:0006624]; vitamin D metabolic process [GO:0042359]	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; perinuclear region of cytoplasm [GO:0048471]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]	cysteine-type endopeptidase activity [GO:0004197]; peptidase activity [GO:0008233]; tau protein binding [GO:0048156]
d1nb5.3_d4mzsa___1	Metazoa	Metazoa	Chordata	Chordata	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]
d1nb5i__d2bk7d2__1	Metazoa		Chordata		cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]		cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]	
d1nb5j__d2w9pm___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	cysteine-type endopeptidase inhibitor activity [GO:0004869]	cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]		cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]	cysteine-type endopeptidase inhibitor activity [GO:0004869]
d1nb5l__d4mon.4__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]		cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]	
d1nbca__d5lxvc___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cell wall organization [GO:0071555]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]; cell wall organization [GO:0071555]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]
d1nbcb__d5gy0a2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cell wall organization [GO:0071555]; cellulose catabolic process [GO:0030245]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]; cell wall organization [GO:0071555]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1nbfd__d5chwc2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1nbga__d2vbta___1				Euryarchaeota		magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; riboflavin kinase activity [GO:0008531]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]		FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]				magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; riboflavin kinase activity [GO:0008531]
d1nbha__d1m6ex___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]		cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]		folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]
d1nbhb__d1mhta___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	DNA restriction-modification system [GO:0009307]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]		folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d1nbhd__d3kpvb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d1nbid__d2br3e___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]		folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	methyltransferase activity [GO:0008168]
d1nbma2_d3oehv1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1nbmb1_d2jdid1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1nbmc1_d4yxwf3__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1nbmc2_d2jj1f1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1nbmd1_d2jizj3__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1nbmd2_d1w0kc2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1nbme2_d2v7qa1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1nbmf1_d5hkke3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1nbmf2_d2jj1h1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1nbqa1_d3w9ec___1	Metazoa		Chordata		bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]; cadherin binding [GO:0045296]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618]; actomyosin structure organization [GO:0031032]; bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; establishment of endothelial intestinal barrier [GO:0090557]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to bicellular tight junction [GO:1902396]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of cytoskeleton organization [GO:0051493]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]; transforming growth factor beta receptor signaling pathway [GO:0007179]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; metal ion binding [GO:0046872]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	actomyosin structure organization [GO:0031032]; bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; establishment of endothelial intestinal barrier [GO:0090557]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to bicellular tight junction [GO:1902396]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of cytoskeleton organization [GO:0051493]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]; transforming growth factor beta receptor signaling pathway [GO:0007179]	entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cadherin binding [GO:0045296]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618]	metal ion binding [GO:0046872]
d1nbqb1_d4f58m2__1	Metazoa		Chordata		bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]; cadherin binding [GO:0045296]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618]; actomyosin structure organization [GO:0031032]; bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; establishment of endothelial intestinal barrier [GO:0090557]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to bicellular tight junction [GO:1902396]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of cytoskeleton organization [GO:0051493]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]; transforming growth factor beta receptor signaling pathway [GO:0007179]		actomyosin structure organization [GO:0031032]; bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; establishment of endothelial intestinal barrier [GO:0090557]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to bicellular tight junction [GO:1902396]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of cytoskeleton organization [GO:0051493]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]; transforming growth factor beta receptor signaling pathway [GO:0007179]		bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]		cadherin binding [GO:0045296]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618]	
d1nbqb2_d1wiua___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]; cadherin binding [GO:0045296]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618]; actomyosin structure organization [GO:0031032]; bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; establishment of endothelial intestinal barrier [GO:0090557]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to bicellular tight junction [GO:1902396]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of cytoskeleton organization [GO:0051493]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]; transforming growth factor beta receptor signaling pathway [GO:0007179]	A band [GO:0031672]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; structural constituent of muscle [GO:0008307]; adult locomotory behavior [GO:0008344]; behavioral response to nicotine [GO:0035095]; muscle contraction [GO:0006936]; negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of locomotion [GO:0040017]; positive regulation of sarcomere organization [GO:0060298]; positive regulation of striated muscle contraction [GO:0045989]; sarcomere organization [GO:0045214]; striated muscle myosin thick filament assembly [GO:0071688]	actomyosin structure organization [GO:0031032]; bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; establishment of endothelial intestinal barrier [GO:0090557]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to bicellular tight junction [GO:1902396]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of cytoskeleton organization [GO:0051493]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]; transforming growth factor beta receptor signaling pathway [GO:0007179]	adult locomotory behavior [GO:0008344]; behavioral response to nicotine [GO:0035095]; muscle contraction [GO:0006936]; negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of locomotion [GO:0040017]; positive regulation of sarcomere organization [GO:0060298]; positive regulation of striated muscle contraction [GO:0045989]; sarcomere organization [GO:0045214]; striated muscle myosin thick filament assembly [GO:0071688]	bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]	A band [GO:0031672]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cadherin binding [GO:0045296]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; structural constituent of muscle [GO:0008307]
d1nbua__d1fb1b___1		Metazoa	Actinobacteria	Chordata	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]	calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]
d1nbub__d1rsia___1			Actinobacteria	Firmicutes	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]
d1nbue__d1n3rj___1			Actinobacteria	Proteobacteria	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1nbuf__d1rrya___1			Actinobacteria	Firmicutes	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]
d1nbug__d1rsda___1			Actinobacteria	Firmicutes	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]
d1nbvh2_d5wl1a2__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1nbvl1_d3dvnl2__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1nbwb__d1egmb___1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; glycerol dehydratase activity [GO:0046405]; metal ion binding [GO:0046872]	propanediol dehydratase activity [GO:0050215]					ATP binding [GO:0005524]; glycerol dehydratase activity [GO:0046405]; metal ion binding [GO:0046872]	propanediol dehydratase activity [GO:0050215]
d1nbwb__d2d0od___1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; glycerol dehydratase activity [GO:0046405]; metal ion binding [GO:0046872]						ATP binding [GO:0005524]; glycerol dehydratase activity [GO:0046405]; metal ion binding [GO:0046872]	
d1nbya1_d1cr9h2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1nbyb2_d4y4ff___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1nbza1_d1ck0h1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1nbza2_d4m61c2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1nbza2_d4x6dg1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1nbzb2_d1ynkl1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1nc1a1_d3qpbm___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]	uridine phosphorylase activity [GO:0004850]
d1nc2a2_d1zlsh1__1												
d1nc2c1_d5jdjd1__1		Metazoa		Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1nc2c2_d1b88b___1		Metazoa		Chordata								
d1nc3a1_d1k3fe___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]	cytosol [GO:0005829]	adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]
d1nc3b__d3p0fa___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]	cytosol [GO:0005829]; type III intermediate filament [GO:0045098]; identical protein binding [GO:0042802]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine metabolic process [GO:0046108]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine metabolic process [GO:0046108]	cytosol [GO:0005829]	cytosol [GO:0005829]; type III intermediate filament [GO:0045098]	adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]	identical protein binding [GO:0042802]; uridine phosphorylase activity [GO:0004850]
d1nc4a2_d2j88l1__1		Metazoa		Arthropoda		extracellular region [GO:0005576]; hyalurononglucosaminidase activity [GO:0004415]; carbohydrate metabolic process [GO:0005975]; defense response [GO:0006952]		carbohydrate metabolic process [GO:0005975]; defense response [GO:0006952]		extracellular region [GO:0005576]		hyalurononglucosaminidase activity [GO:0004415]
d1nc4b2_d3sdyl2__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d1nc4b2_d4i0cd1__1		Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]		antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1nc9a__d2qcba2__1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1ncah1_d2c7ue2__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ncah1_d3fmgl1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell endoplasmic reticulum lumen [GO:0044166]; T=13 icosahedral viral capsid [GO:0039621]; viral outer capsid [GO:0039624]; metal ion binding [GO:0046872]; receptor-mediated virion attachment to host cell [GO:0046813]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	receptor-mediated virion attachment to host cell [GO:0046813]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell endoplasmic reticulum lumen [GO:0044166]; T=13 icosahedral viral capsid [GO:0039621]; viral outer capsid [GO:0039624]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1ncah2_d3l1ol2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	
d1ncal1_d3of6b1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	integral component of membrane [GO:0016021]; negative regulation of thymocyte apoptotic process [GO:0070244]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	negative regulation of thymocyte apoptotic process [GO:0070244]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	integral component of membrane [GO:0016021]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	
d1ncal2_d1gigh2__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	
d1ncal2_d1igta1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ncbl2_d2dqul1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ncbn__d4qnpa___1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ncch2_d3umta1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	
d1nccl2_d2qr0e1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ncdh1_d4ku1a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ncdh2_d4jo2l2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ncdl2_d3dhja___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ncdn__d3tiad___1	Metazoa		Chordata	Negarnaviricota	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1nceb__d1f4ea___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytosol [GO:0005829]	cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]
d1ncna__d1bbjb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 biosynthetic process [GO:0045404]; positive regulation of lymphotoxin A biosynthetic process [GO:0043017]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 biosynthetic process [GO:0045404]; positive regulation of lymphotoxin A biosynthetic process [GO:0043017]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	coreceptor activity [GO:0015026]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ncnb__d1q72l1__1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 biosynthetic process [GO:0045404]; positive regulation of lymphotoxin A biosynthetic process [GO:0043017]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 biosynthetic process [GO:0045404]; positive regulation of lymphotoxin A biosynthetic process [GO:0043017]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		coreceptor activity [GO:0015026]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]	
d1ncnb__d4ndma2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 biosynthetic process [GO:0045404]; positive regulation of lymphotoxin A biosynthetic process [GO:0043017]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 biosynthetic process [GO:0045404]; positive regulation of lymphotoxin A biosynthetic process [GO:0043017]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		coreceptor activity [GO:0015026]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]	
d1ncoa__d1hzla___1			Actinobacteria	Actinobacteria	DNA binding [GO:0003677]; defense response to bacterium [GO:0042742]	DNA binding [GO:0003677]; defense response to bacterium [GO:0042742]	defense response to bacterium [GO:0042742]	defense response to bacterium [GO:0042742]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1ncqa__d5k0ua___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ncra__d1f8v.1__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]
d1ncta1_d1agba1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1nd0b2_d3l5yl3__1	Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d1nd0c1_d2clvh1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1nd0d2_d1qblh2__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	metal ion binding [GO:0046872]	
d1nd0e1_d5x8lo2__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	metal ion binding [GO:0046872]	
d1nd0e2_d3hntl1__1	Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d1nd0g2_d4pjef2__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1nd0h1_d1kcvl1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1nd0h2_d3dx8b___1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1nd2a__d1ny722__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	transport of virus in host, cell to cell [GO:0046740]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1nd2a__d5cfca___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1nd3a__d5w3ea___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	
d1nd6d__d3k4qa___1	Metazoa	Fungi	Chordata	Ascomycota	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]; adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	extracellular region [GO:0005576]; 3-phytase activity [GO:0016158]	adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]		azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	extracellular region [GO:0005576]	5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]	3-phytase activity [GO:0016158]
d1ndab2_d1mo9a2__1				Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; 2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]	2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]
d1ndca__d3ee3a1__1					cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1nddc__d2vrrb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d1ndfa2_d1pd5c___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	response to antibiotic [GO:0046677]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]		carnitine O-acetyltransferase activity [GO:0004092]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d1ndfb1_d3u9fl___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	response to antibiotic [GO:0046677]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]		carnitine O-acetyltransferase activity [GO:0004092]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d1ndga1_d1cbvh2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	metal ion binding [GO:0046872]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	metal ion binding [GO:0046872]
d1ndgc__d1lhla___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ndha2_d2eixb2__1	Metazoa		Chordata		endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]	integral component of membrane [GO:0016021]; 2 iron, 2 sulfur cluster binding [GO:0051537]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; flavin adenine dinucleotide binding [GO:0050660]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cholesterol biosynthetic process [GO:0006695]	pyrimidine nucleotide biosynthetic process [GO:0006221]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	integral component of membrane [GO:0016021]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	2 iron, 2 sulfur cluster binding [GO:0051537]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; flavin adenine dinucleotide binding [GO:0050660]
d1ndia2_d2h4tb3__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	carnitine O-acetyltransferase activity [GO:0004092]	carnitine O-palmitoyltransferase activity [GO:0004095]
d1ndib1_d2ii3g___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]		endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	carnitine O-acetyltransferase activity [GO:0004092]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1ndjb__d4jnjd___1			Actinobacteria		extracellular region [GO:0005576]; biotin binding [GO:0009374]				extracellular region [GO:0005576]		biotin binding [GO:0009374]	
d1ndlc__d4uofc___1	Metazoa	Metazoa	Arthropoda	Arthropoda	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nuclear microtubule [GO:0005880]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; nucleoside diphosphate kinase activity [GO:0004550]; adherens junction organization [GO:0034332]; CTP biosynthetic process [GO:0006241]; epithelial cell migration, open tracheal system [GO:0007427]; establishment or maintenance of polarity of follicular epithelium [GO:0016334]; GTP biosynthetic process [GO:0006183]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide metabolic process [GO:0009117]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of tube architecture, open tracheal system [GO:0035152]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	adherens junction organization [GO:0034332]; CTP biosynthetic process [GO:0006241]; epithelial cell migration, open tracheal system [GO:0007427]; establishment or maintenance of polarity of follicular epithelium [GO:0016334]; GTP biosynthetic process [GO:0006183]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide metabolic process [GO:0009117]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of tube architecture, open tracheal system [GO:0035152]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nuclear microtubule [GO:0005880]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; GTP binding [GO:0005525]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d1ndma1_d1igfj2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1ndmb2_d2edna1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytosol [GO:0005829]; myosin filament [GO:0032982]; actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytosol [GO:0005829]; myosin filament [GO:0032982]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]
d1ndoa2_d3gcff2__1			Proteobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				dioxygenase activity [GO:0051213]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1ndoc2_d4a83a___1		Viridiplantae	Proteobacteria	Streptophyta	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]	dioxygenase activity [GO:0051213]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d1ndod__d5cf2d___1			Proteobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	limonene-1,2-epoxide hydrolase activity [GO:0018744]	aromatic compound catabolic process [GO:0019439]				dioxygenase activity [GO:0051213]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d1ndoe1_d3gcfc1__1			Proteobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				dioxygenase activity [GO:0051213]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1ndof__d5stdc1__1		Fungi	Proteobacteria	Ascomycota	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	endosome [GO:0005768]; metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]; melanin biosynthetic process [GO:0042438]	aromatic compound catabolic process [GO:0019439]	melanin biosynthetic process [GO:0042438]		endosome [GO:0005768]	dioxygenase activity [GO:0051213]	metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]
d1ndra1_d1l9rc1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1ndra1_d3paza___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1ndra2_d5pcya___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1ndrb2_d4cspf2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1ndsa2_d2vw6a2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1ndsb1_d2iwed___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1ndsc1_d1e67b___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1ndsc2_d1ws7b___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1ndsc2_d2xwzb2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1ndva__d2q08j___1	Metazoa		Chordata	Firmicutes	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]; adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	metal ion binding [GO:0046872]	adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]		cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]		adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1ndwa__d4eraa___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]; adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]		cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]		adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1ndya__d1w1if___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]; adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1ne4a2_d4i0aa1__1	Metazoa		Chordata	Proteobacteria	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d1ne6a2_d5l0na___1	Metazoa	Metazoa	Chordata	Chordata	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]
d1ne7b__d4eu4b1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; single fertilization [GO:0007338]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; single fertilization [GO:0007338]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d1ne7d__d1fs5a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; single fertilization [GO:0007338]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; single fertilization [GO:0007338]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]	glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]
d1neea1_d2d74b1__1			Euryarchaeota	Euryarchaeota	translation initiation factor activity [GO:0003743]	translation initiation factor activity [GO:0003743]					translation initiation factor activity [GO:0003743]	translation initiation factor activity [GO:0003743]
d1neja__d2uuma___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1nejc__d2zfod___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1nekb2_d3nvwa1__1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	xanthine catabolic process [GO:0009115]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1nena1_d1kf6m1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1nena3_d1kssa3__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	outer membrane-bounded periplasmic space [GO:0030288]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]
d1nenb2_d3av8d___1			Proteobacteria	Cyanobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1nepa__d1wlhb2__1	Metazoa		Chordata		endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; lysosome [GO:0005764]; cholesterol binding [GO:0015485]; sterol binding [GO:0032934]; cholesterol efflux [GO:0033344]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; intracellular cholesterol transport [GO:0032367]; sterol transport [GO:0015918]	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]; actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]; actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	cholesterol efflux [GO:0033344]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; intracellular cholesterol transport [GO:0032367]; sterol transport [GO:0015918]	actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; lysosome [GO:0005764]	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]	cholesterol binding [GO:0015485]; sterol binding [GO:0032934]	actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]
d1nese__d2zu1a___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host gene expression [GO:0039656]; modulation by virus of host NIK/NF-kappaB signaling [GO:0061765]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive regulation by virus of host cytokine production [GO:0044832]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host gene expression [GO:0039656]; modulation by virus of host NIK/NF-kappaB signaling [GO:0061765]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive regulation by virus of host cytokine production [GO:0044832]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1neza1_d5iw1d1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1neza2_d4i5ba1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1nezg1_d5dd3l1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1nf2a__d2r8ea___1			Thermotogae	Proteobacteria	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]		magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1nf2b__d1xvia___1			Thermotogae	Proteobacteria	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; mannosyl-3-phosphoglycerate phosphatase activity [GO:0050531]; phosphatase activity [GO:0016791]; mannosylglycerate biosynthetic process [GO:0051479]		mannosylglycerate biosynthetic process [GO:0051479]	cytosol [GO:0005829]	cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]	magnesium ion binding [GO:0000287]; mannosyl-3-phosphoglycerate phosphatase activity [GO:0050531]; phosphatase activity [GO:0016791]
d1nf3a1_d4wzbg___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	nitrogen fixation [GO:0009399]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	molybdenum-iron nitrogenase complex [GO:0016612]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1nf3b1_d1rrpc___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1nf3c__d2z17a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleoplasm [GO:0005654]; regulation of cell adhesion [GO:0030155]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	regulation of cell adhesion [GO:0030155]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleoplasm [GO:0005654]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	
d1nf4a__d3a68a___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1nf4d__d1xvbc___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1nf4e__d2yjkf___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d1nf4h__d2jd7j___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d1nf4m__d1fzic___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1nf4o__d3kx9b___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]
d1nf4p__d3e1ok___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1nf5c__d1gb9a___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1nf6a__d3qd8s1__1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1nf6b__d2c41j___1			Proteobacteria	Cyanobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1nf6c__d1r03a___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; nucleus [GO:0005634]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; nucleus [GO:0005634]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1nf6f__d4toga___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1nf6m__d4tocw___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1nf6n__d2jd6i___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d1nf6o__d2iy4x___1			Proteobacteria	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1nf6p__d1fz2b___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1nfaa__d2j1wa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; FK506 binding [GO:0005528]; mitogen-activated protein kinase p38 binding [GO:0048273]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription coactivator binding [GO:0001225]; RNA polymerase II transcription factor binding [GO:0001085]; transcription factor binding [GO:0008134]; aortic valve morphogenesis [GO:0003180]; calcineurin-NFAT signaling cascade [GO:0033173]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; intracellular signal transduction [GO:0035556]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pulmonary valve morphogenesis [GO:0003184]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	aortic valve morphogenesis [GO:0003180]; calcineurin-NFAT signaling cascade [GO:0033173]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; intracellular signal transduction [GO:0035556]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pulmonary valve morphogenesis [GO:0003184]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; FK506 binding [GO:0005528]; mitogen-activated protein kinase p38 binding [GO:0048273]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription coactivator binding [GO:0001225]; RNA polymerase II transcription factor binding [GO:0001085]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1nfda1_d2g2rl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1nfdd1_d4lspl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	structural molecule activity [GO:0005198]
d1nfdd2_d1l0xa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1nfde1_d3m17b___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1nfde2_d1axsl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1nfdf1_d4dvbb2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1nfdg1_d2vxso2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cell-cell signaling [GO:0007267]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cell death [GO:0008219]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cytokine activity [GO:0005125]
d1nfdg2_d5f7md1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1nfdh2_d3ha0e2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1nfhb__d1h0xb___1			Euryarchaeota	Crenarchaeota	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; chromosome condensation [GO:0030261]		chromosome condensation [GO:0030261]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d1nfhb__d3u6ya___1			Euryarchaeota	Crenarchaeota	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]			chromosome [GO:0005694]; cytoplasm [GO:0005737]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]
d1nfia1_d1bvza1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]		actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1nfia2_d1owrm2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1nfic1_d1bfsa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1nfic2_d1owrp2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1nfqa__d5kkcd1__1		Metazoa	Actinobacteria	Chordata	plasma membrane [GO:0005886]; androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; C21-steroid hormone metabolic process [GO:0008207]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	C21-steroid hormone metabolic process [GO:0008207]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	L-lactate dehydrogenase activity [GO:0004459]
d1nfqc__d3afnc___1			Actinobacteria	Proteobacteria	plasma membrane [GO:0005886]; androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; C21-steroid hormone metabolic process [GO:0008207]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	nucleotide binding [GO:0000166]	C21-steroid hormone metabolic process [GO:0008207]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]		plasma membrane [GO:0005886]		androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	nucleotide binding [GO:0000166]
d1nfqd__d5bsee1__1		Viridiplantae	Actinobacteria	Streptophyta	plasma membrane [GO:0005886]; androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; C21-steroid hormone metabolic process [GO:0008207]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	cell wall [GO:0005618]; nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]; L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]	C21-steroid hormone metabolic process [GO:0008207]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]	plasma membrane [GO:0005886]	cell wall [GO:0005618]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1nfsb1_d5ghia___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTP diphosphatase activity [GO:0036219]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]; aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTPase activity [GO:0003924]; GTP diphosphatase activity [GO:0036219]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]
d1nfva__d4todi___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1nfvb__d3rgdg___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1nfvc__d5jkkb___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1nfvi__d2fl0f___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1nfvi__d3qd8e1__1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1nfvk__d1oqud___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1nfvl__d4m1ha1__1			Proteobacteria	Chlamydiae	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1nfvm__d4d8fa1__1			Proteobacteria	Chlamydiae	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1nfwa__d1jxp.2__1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1nfxa__d1hia.2__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	secretory granule [GO:0030141]; serine-type endopeptidase activity [GO:0004252]; regulation of systemic arterial blood pressure [GO:0003073]; zymogen activation [GO:0031638]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	regulation of systemic arterial blood pressure [GO:0003073]; zymogen activation [GO:0031638]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	secretory granule [GO:0030141]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1ng0c__d1rmu1___1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; peptidase activity [GO:0008233]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	metal ion binding [GO:0046872]; peptidase activity [GO:0008233]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ng1a2_d1khta___1			Deinococcus-Thermus	Euryarchaeota	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytoplasm [GO:0005737]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]		signal recognition particle [GO:0048500]	cytoplasm [GO:0005737]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]
d1ng4b2_d1kifd2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]; cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d1ng9a4_d1wbba4__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; mismatch repair complex [GO:0032300]; adenine/cytosine mispair binding [GO:0032136]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA-dependent ATPase activity [GO:0008094]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]; cellular response to DNA damage stimulus [GO:0006974]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	cytosol [GO:0005829]; mismatch repair complex [GO:0032300]; adenine/cytosine mispair binding [GO:0032136]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA-dependent ATPase activity [GO:0008094]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]; cellular response to DNA damage stimulus [GO:0006974]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	cellular response to DNA damage stimulus [GO:0006974]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	cellular response to DNA damage stimulus [GO:0006974]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	cytosol [GO:0005829]; mismatch repair complex [GO:0032300]	cytosol [GO:0005829]; mismatch repair complex [GO:0032300]	adenine/cytosine mispair binding [GO:0032136]; ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA-dependent ATPase activity [GO:0008094]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]	adenine/cytosine mispair binding [GO:0032136]; ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA-dependent ATPase activity [GO:0008094]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]
d1ngaa2_d3ldnb1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1ngba1_d1atra2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d1ngba1_d1tuub1__1	Metazoa		Chordata	Euryarchaeota	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]
d1ngba2_d4jaxe2__1	Metazoa	Fungi	Chordata	Ascomycota	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cell [GO:0005623]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]
d1ngca1_d1kaxa1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d1ngda2_d3cj1a1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adenosine-diphosphatase activity [GO:0043262]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	adenosine-diphosphatase activity [GO:0043262]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]
d1ngda2_d4h5wb2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1ngea1_d3d2fb2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]
d1ngga1_d3djcj1__1	Metazoa		Chordata	Proteobacteria	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	coenzyme A biosynthetic process [GO:0015937]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d1ngha1_d1ngaa2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d1ngia1_d3ldlb2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1ngkb__d1a9we___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ngkc__d1uvxa___1		Viridiplantae	Actinobacteria	Chlorophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	chloroplast [GO:0009507]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	chloroplast [GO:0009507]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ngki__d5touc___1			Actinobacteria	Cyanobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	
d1ngkj__d5x2rk___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ngkl__d2qrwh___1			Actinobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1ngma1_d3ocib2__1	Fungi	Fungi	Ascomycota	Microsporidia	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]; DNA-templated transcription, initiation [GO:0006352]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA-templated transcription, initiation [GO:0006352]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]		chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]
d1ngma2_d1qncb1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1ngmi1_d1pcza2__1	Fungi		Ascomycota	Euryarchaeota	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA-templated transcription, initiation [GO:0006352]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]		chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1ngmi2_d1pvsb2__1	Fungi		Ascomycota	Proteobacteria	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1ngmi2_d1qneb2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1ngph1_d2p7ta1__1	Metazoa		Chordata	Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1ngql1_d2h2pd1__1	Metazoa	Metazoa	Chordata	Chordata								
d1ngql2_d2mcpl1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ngra__d4rhwc___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated endocytic vesicle [GO:0045334]; coated vesicle [GO:0030135]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuronal cell body membrane [GO:0032809]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; amyloid-beta binding [GO:0001540]; calmodulin binding [GO:0005516]; coreceptor activity [GO:0015026]; death receptor activity [GO:0005035]; identical protein binding [GO:0042802]; nerve growth factor binding [GO:0048406]; neurotrophin binding [GO:0043121]; neurotrophin TRKA receptor binding [GO:0005168]; preprotein binding [GO:0070678]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; apoptotic process [GO:0006915]; cellular glucose homeostasis [GO:0001678]; cellular response to oxidative stress [GO:0034599]; circadian regulation of gene expression [GO:0032922]; glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; positive regulation of apoptotic process [GO:0043065]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of myelination [GO:0031643]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of cell death [GO:0010941]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to lipopolysaccharide [GO:0032496]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; skeletal muscle cell differentiation [GO:0035914]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	apoptotic process [GO:0006915]; cellular glucose homeostasis [GO:0001678]; cellular response to oxidative stress [GO:0034599]; circadian regulation of gene expression [GO:0032922]; glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; positive regulation of apoptotic process [GO:0043065]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of myelination [GO:0031643]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of cell death [GO:0010941]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to lipopolysaccharide [GO:0032496]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; skeletal muscle cell differentiation [GO:0035914]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated endocytic vesicle [GO:0045334]; coated vesicle [GO:0030135]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuronal cell body membrane [GO:0032809]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	amyloid-beta binding [GO:0001540]; calmodulin binding [GO:0005516]; coreceptor activity [GO:0015026]; death receptor activity [GO:0005035]; identical protein binding [GO:0042802]; nerve growth factor binding [GO:0048406]; neurotrophin binding [GO:0043121]; neurotrophin TRKA receptor binding [GO:0005168]; preprotein binding [GO:0070678]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; Rab GTPase binding [GO:0017137]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d1ngsa2_d2jibb2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	pentose-phosphate shunt [GO:0006098]	oxalate catabolic process [GO:0033611]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d1ngsa3_d2bp7f2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]	pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]
d1ngsb1_d1w88d1__1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1ngsb3_d2bfeb2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	pentose-phosphate shunt [GO:0006098]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]
d1ngsb3_d2r8pa3__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	pentose-phosphate shunt [GO:0006098]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d1ngva__d1zkma___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; nucleotidyltransferase activity [GO:0016779]; ubiquitin-like modifier activating enzyme activity [GO:0008641]; zinc ion binding [GO:0008270]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]		thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; nucleotidyltransferase activity [GO:0016779]; ubiquitin-like modifier activating enzyme activity [GO:0008641]; zinc ion binding [GO:0008270]
d1ngwa2_d1l6za2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary membrane [GO:0060170]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lateral plasma membrane [GO:0016328]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; actin binding [GO:0003779]; bile acid transmembrane transporter activity [GO:0015125]; calmodulin binding [GO:0005516]; filamin binding [GO:0031005]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; Toll-like receptor binding [GO:0035325]; virus receptor activity [GO:0001618]; bile acid and bile salt transport [GO:0015721]; blood vessel development [GO:0001568]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; common myeloid progenitor cell proliferation [GO:0035726]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; insulin catabolic process [GO:1901143]; insulin receptor internalization [GO:0038016]; negative regulation of bone resorption [GO:0045779]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of vascular permeability [GO:0043116]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of vasculogenesis [GO:2001214]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell growth [GO:0001558]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell migration [GO:0010594]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of homophilic cell adhesion [GO:1903385]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of sprouting angiogenesis [GO:1903670]; wound healing, spreading of cells [GO:0044319]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	bile acid and bile salt transport [GO:0015721]; blood vessel development [GO:0001568]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; common myeloid progenitor cell proliferation [GO:0035726]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; insulin catabolic process [GO:1901143]; insulin receptor internalization [GO:0038016]; negative regulation of bone resorption [GO:0045779]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of vascular permeability [GO:0043116]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of vasculogenesis [GO:2001214]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell growth [GO:0001558]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell migration [GO:0010594]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of homophilic cell adhesion [GO:1903385]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of sprouting angiogenesis [GO:1903670]; wound healing, spreading of cells [GO:0044319]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell surface [GO:0009986]; ciliary membrane [GO:0060170]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lateral plasma membrane [GO:0016328]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin binding [GO:0003779]; bile acid transmembrane transporter activity [GO:0015125]; calmodulin binding [GO:0005516]; filamin binding [GO:0031005]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; Toll-like receptor binding [GO:0035325]; virus receptor activity [GO:0001618]
d1ngwb1_d1y0lc2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ngwh1_d5o4ea2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ngwl1_d1cicc2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ngxb1_d4ww2b2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ngxb2_d2ak4t2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ngxh1_d1fnga1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]		
d1ngya2_d1oakl1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ngza2_d1mlcc1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ngzb1_d5i30l2__1												
d1nh0b__d1k6pb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1nh2a1_d1mp9b1__1	Fungi		Ascomycota	Crenarchaeota	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA-templated transcription, initiation [GO:0006352]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]		chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1nh2a1_d3cwtc2__1	Fungi		Ascomycota	Proteobacteria	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1nhba__d1cx7a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1nhba__d2d4ka___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1nhcb__d2nstb___1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]
d1nhcc__d1ee6a___1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; pectate lyase activity [GO:0030570]; polygalacturonase activity [GO:0004650]; pectin biosynthetic process [GO:0045489]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	pectin biosynthetic process [GO:0045489]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	calcium ion binding [GO:0005509]; pectate lyase activity [GO:0030570]; polygalacturonase activity [GO:0004650]
d1nhcd__d1idka___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; pectin lyase activity [GO:0047490]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	pectin lyase activity [GO:0047490]
d1nhce__d2o0wa___1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]
d1nhcf__d2nt6a___1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]
d1nhna__d1wz6a1__1	Metazoa	Metazoa	Chordata	Chordata	condensed chromosome [GO:0000793]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; DNA binding [GO:0003677]; adaptive immune response [GO:0002250]; apoptotic cell clearance [GO:0043277]; autophagy [GO:0006914]; chemotaxis [GO:0006935]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0017055]; neutrophil clearance [GO:0097350]; positive regulation of DNA ligation [GO:0051106]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; regulation of T cell mediated immune response to tumor cell [GO:0002840]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; DNA binding [GO:0003677]; bone development [GO:0060348]	adaptive immune response [GO:0002250]; apoptotic cell clearance [GO:0043277]; autophagy [GO:0006914]; chemotaxis [GO:0006935]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0017055]; neutrophil clearance [GO:0097350]; positive regulation of DNA ligation [GO:0051106]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; regulation of T cell mediated immune response to tumor cell [GO:0002840]	bone development [GO:0060348]	condensed chromosome [GO:0000793]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1nhoa__d1h4od___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]
d1nhsa3_d1feac3__1			Firmicutes		cell [GO:0005623]; flavin adenine dinucleotide binding [GO:0050660]; NADH peroxidase activity [GO:0016692]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	flavin adenine dinucleotide binding [GO:0050660]; NADH peroxidase activity [GO:0016692]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]
d1ni2a1_d4p7ia2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d1ni2a3_d2zpya3__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]	epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d1ni2b2_d3dxec___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid-beta clearance [GO:1900221]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi lumen [GO:0005796]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]	acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]
d1ni2b3_d2mbbb___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1ni7a1_d4eb5d___1			Proteobacteria	Euryarchaeota	sulfur carrier activity [GO:0097163]; cyclic threonylcarbamoyladenosine biosynthetic process [GO:0061504]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; iron-sulfur cluster assembly [GO:0016226]	cyclic threonylcarbamoyladenosine biosynthetic process [GO:0061504]	iron-sulfur cluster assembly [GO:0016226]			sulfur carrier activity [GO:0097163]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]
d1niaa2_d2ftaa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1niab1_d2occo1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1niab2_d1jvok___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1niab2_d1rzqb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1niba1_d4gp4b2__1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1nibb2_d1ws7d___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1nibc2_d1e65a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1nibc2_d2xx0a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1nida1_d3h4fb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1nida2_d1iuza___1		Viridiplantae	Proteobacteria	Chlorophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; defense response to virus [GO:0051607]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	defense response to virus [GO:0051607]	periplasmic space [GO:0042597]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1niea2_d2ppac1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1nifa1_d1f56c___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]
d1nija1_d1honb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; cellular response to DNA damage stimulus [GO:0006974]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; 'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	cellular response to DNA damage stimulus [GO:0006974]	'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]	adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d1nina__d4ko5a___1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1nirb1_d1aoqb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1nisa1_d1b0ka1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; metal ion binding [GO:0046872]; tricarboxylic acid cycle [GO:0006099]	citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]	4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; metal ion binding [GO:0046872]
d1nisa2_d1c96a2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]
d1niva__d3a0cd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]			extracellular region [GO:0005576]		mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]
d1nivc__d2d04a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]			extracellular region [GO:0005576]		mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]
d1nj1a3_d3nenb2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	prolyl-tRNA aminoacylation [GO:0006433]	aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d1nj5a3_d2hnib1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	prolyl-tRNA aminoacylation [GO:0006433]	cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d1nj6a2_d1h4qb3__1			Euryarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	prolyl-tRNA aminoacylation [GO:0006433]	prolyl-tRNA aminoacylation [GO:0006433]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]
d1nj6a3_d3p8tb___1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; tRNA aminoacylation for protein translation [GO:0006418]	prolyl-tRNA aminoacylation [GO:0006433]	tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]
d1nj8a1_d4ttvb2__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	prolyl-tRNA aminoacylation [GO:0006433]	threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; proline-tRNA ligase activity [GO:0004827]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]
d1nj8c1_d1koga1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	prolyl-tRNA aminoacylation [GO:0006433]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; proline-tRNA ligase activity [GO:0004827]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1nj8d1_d1hc7c1__1			Euryarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	prolyl-tRNA aminoacylation [GO:0006433]	prolyl-tRNA aminoacylation [GO:0006433]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; proline-tRNA ligase activity [GO:0004827]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; proline-tRNA ligase activity [GO:0004827]
d1nj9a2_d4zqka___1		Metazoa		Chordata		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		
d1nj9b2_d1yntb1__1				Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]		IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]
d1nj9h1_d5u6qg1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1nj9h2_d4kk8f1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1njba__d5x69a___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	thymidylate synthase activity [GO:0004799]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1njca__d4h1ib___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	thymidylate synthase activity [GO:0004799]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1njea__d1b02a___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytosol [GO:0005829]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d1njfc__d4h9ga1__1			Proteobacteria	Deinococcus-Thermus	DNA polymerase III, clamp loader complex [GO:0043846]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; nucleoside-triphosphatase activity [GO:0017111]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	DNA-dependent DNA replication [GO:0006261]; DNA replication [GO:0006260]		DNA polymerase III, clamp loader complex [GO:0043846]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; nucleoside-triphosphatase activity [GO:0017111]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1njid__d1xbpb1__1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	cytosolic large ribosomal subunit [GO:0022625]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d1njid__d4rd6a2__1			Euryarchaeota	Crenarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	translation [GO:0006412]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	ribosome [GO:0005840]	cytosol [GO:0005829]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1njil__d2vhmk1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1njin__d1vq7m1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1njio__d2uu9k1__1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1njis__d1i4ja___1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	large ribosomal subunit [GO:0015934]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	large ribosomal subunit [GO:0015934]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1nk5a1_d1q9xd1__1			Firmicutes		3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1nkga3_d3vdad5__1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1nkhb__d1mp3a___1	Metazoa		Chordata	Proteobacteria	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	extracellular polysaccharide biosynthetic process [GO:0045226]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]		alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1nkhc__d119la___1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	host cell cytoplasm [GO:0030430]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	lysozyme activity [GO:0003796]
d1nksd__d5jmta1__1			Crenarchaeota		cytoplasm [GO:0005737]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1nl0h1_d1ic7h___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1nl0l2_d1rhhd2__1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]		blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]		collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]	
d1nl3a4_d1t6nb___1		Metazoa	Actinobacteria	Chordata	cell envelope Sec protein transport complex [GO:0031522]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled protein transmembrane transporter activity [GO:0015462]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; intracellular protein transmembrane transport [GO:0065002]; protein import [GO:0017038]; protein targeting [GO:0006605]; protein transport by the Sec complex [GO:0043952]	cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; transcription export complex [GO:0000346]; ATP binding [GO:0005524]; ATP-dependent protein binding [GO:0043008]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-dependent ATPase activity [GO:0008186]; U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070]; liver development [GO:0001889]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; RNA export from nucleus [GO:0006405]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; intracellular protein transmembrane transport [GO:0065002]; protein import [GO:0017038]; protein targeting [GO:0006605]; protein transport by the Sec complex [GO:0043952]	liver development [GO:0001889]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; RNA export from nucleus [GO:0006405]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784]	cell envelope Sec protein transport complex [GO:0031522]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; transcription export complex [GO:0000346]	ATPase activity [GO:0016887]; ATPase-coupled protein transmembrane transporter activity [GO:0015462]; ATP binding [GO:0005524]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; ATP-dependent protein binding [GO:0043008]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; RNA helicase activity [GO:0003724]; U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070]
d1nl6a__d2efma___1	Metazoa		Chordata		endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]		autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]		endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]	
d1nl6b__d4bqvd___1	Metazoa	Metazoa	Chordata	Chordata	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]
d1nl7a2_d2vtzd1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1nl7c2_d1hn9b2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1nl7d2_d4o9cc2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1nlbh1_d5i16l1__1												
d1nlbh2_d1yegh1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1nlbl2_d5m2md1__1		Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]		cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d1nldh2_d3fo0l2__1												
d1nldl2_d3fctc2__1												
d1nldl2_d4imkd2__1												
d1nlia1_d1yf8a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1nlkr__d3fkbe___1			Proteobacteria		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1nlkr__d3ztsl___1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1nlma__d2zwib___1			Proteobacteria	Proteobacteria	plasma membrane [GO:0005886]; UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity [GO:0051991]; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity [GO:0050511]; carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; lipid glycosylation [GO:0030259]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	metal ion binding [GO:0046872]; transferase activity, transferring glycosyl groups [GO:0016757]	carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; lipid glycosylation [GO:0030259]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]		plasma membrane [GO:0005886]		UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity [GO:0051991]; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity [GO:0050511]	metal ion binding [GO:0046872]; transferase activity, transferring glycosyl groups [GO:0016757]
d1nlna__d4qbbb___1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; viral procapsid [GO:0046729]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; nuclear capsid assembly [GO:0039708]; viral release from host cell [GO:0019076]	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	lysis of host organelle involved in viral entry into host cell [GO:0039664]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; nuclear capsid assembly [GO:0039708]; viral release from host cell [GO:0019076]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; viral procapsid [GO:0046729]	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1nlsa__d2ouhb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]; activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]		activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]
d1nlta2_d2b26b2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; TRC complex [GO:0072380]; ATP binding [GO:0005524]; ATPase activator activity [GO:0001671]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; chaperone-mediated protein complex assembly [GO:0051131]; protein refolding [GO:0042026]; protein targeting to ER [GO:0045047]; protein targeting to mitochondrion [GO:0006626]; response to heat [GO:0009408]; tRNA import into nucleus [GO:0035719]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; nucleus [GO:0005634]; chaperone binding [GO:0051087]; DNA binding [GO:0003677]; misfolded protein binding [GO:0051787]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; chaperone cofactor-dependent protein refolding [GO:0051085]; misfolded protein transport [GO:0070843]; nuclear protein quality control by the ubiquitin-proteasome system [GO:0071630]; protein folding [GO:0006457]; translational initiation [GO:0006413]; tRNA import into nucleus [GO:0035719]	'de novo' protein folding [GO:0006458]; chaperone-mediated protein complex assembly [GO:0051131]; protein refolding [GO:0042026]; protein targeting to ER [GO:0045047]; protein targeting to mitochondrion [GO:0006626]; response to heat [GO:0009408]; tRNA import into nucleus [GO:0035719]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell cycle [GO:0007049]; chaperone cofactor-dependent protein refolding [GO:0051085]; misfolded protein transport [GO:0070843]; nuclear protein quality control by the ubiquitin-proteasome system [GO:0071630]; protein folding [GO:0006457]; translational initiation [GO:0006413]; tRNA import into nucleus [GO:0035719]	cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; TRC complex [GO:0072380]	cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; nucleus [GO:0005634]	ATPase activator activity [GO:0001671]; ATP binding [GO:0005524]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	chaperone binding [GO:0051087]; DNA binding [GO:0003677]; misfolded protein binding [GO:0051787]; unfolded protein binding [GO:0051082]
d1nlta2_d2qlda2__1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; TRC complex [GO:0072380]; ATP binding [GO:0005524]; ATPase activator activity [GO:0001671]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; chaperone-mediated protein complex assembly [GO:0051131]; protein refolding [GO:0042026]; protein targeting to ER [GO:0045047]; protein targeting to mitochondrion [GO:0006626]; response to heat [GO:0009408]; tRNA import into nucleus [GO:0035719]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; sperm head [GO:0061827]; ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; protein folding chaperone [GO:0044183]; transcription corepressor activity [GO:0003714]; unfolded protein binding [GO:0051082]; chaperone cofactor-dependent protein refolding [GO:0051085]; forebrain development [GO:0030900]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; positive regulation of ATPase activity [GO:0032781]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]	'de novo' protein folding [GO:0006458]; chaperone-mediated protein complex assembly [GO:0051131]; protein refolding [GO:0042026]; protein targeting to ER [GO:0045047]; protein targeting to mitochondrion [GO:0006626]; response to heat [GO:0009408]; tRNA import into nucleus [GO:0035719]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	chaperone cofactor-dependent protein refolding [GO:0051085]; forebrain development [GO:0030900]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; positive regulation of ATPase activity [GO:0032781]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]	cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; TRC complex [GO:0072380]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; sperm head [GO:0061827]	ATPase activator activity [GO:0001671]; ATP binding [GO:0005524]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; protein folding chaperone [GO:0044183]; transcription corepressor activity [GO:0003714]; unfolded protein binding [GO:0051082]
d1nlva2_d3fr0a2__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]
d1nlvg__d3q2ba___1	Metazoa		Chordata	Apicomplexa	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; actin monomer binding [GO:0003785]; actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin monomer binding [GO:0003785]
d1nlwb__d5i4za___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein dimerization activity [GO:0046983]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription corepressor activity [GO:0003714]; negative regulation of transcription by RNA polymerase II [GO:0000122]	cell [GO:0005623]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; activating transcription factor binding [GO:0033613]; core promoter binding [GO:0001047]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; E-box binding [GO:0070888]; protein dimerization activity [GO:0046983]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; beta-catenin-TCF complex assembly [GO:1904837]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular iron ion homeostasis [GO:0006879]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to hypoxia [GO:0071456]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; chromosome organization [GO:0051276]; cytokine-mediated signaling pathway [GO:0019221]; energy reserve metabolic process [GO:0006112]; ERK1 and ERK2 cascade [GO:0070371]; fibroblast apoptotic process [GO:0044346]; G1/S transition of mitotic cell cycle [GO:0000082]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell division [GO:0051782]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; oxygen transport [GO:0015671]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA methylation [GO:1905643]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of metanephric cap mesenchymal cell proliferation [GO:0090096]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of telomerase activity [GO:0051973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein-DNA complex disassembly [GO:0032986]; regulation of gene expression [GO:0010468]; regulation of somatic stem cell population maintenance [GO:1904672]; regulation of telomere maintenance [GO:0032204]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to gamma radiation [GO:0010332]; response to growth factor [GO:0070848]	negative regulation of transcription by RNA polymerase II [GO:0000122]	beta-catenin-TCF complex assembly [GO:1904837]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular iron ion homeostasis [GO:0006879]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to hypoxia [GO:0071456]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; chromosome organization [GO:0051276]; cytokine-mediated signaling pathway [GO:0019221]; energy reserve metabolic process [GO:0006112]; ERK1 and ERK2 cascade [GO:0070371]; fibroblast apoptotic process [GO:0044346]; G1/S transition of mitotic cell cycle [GO:0000082]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell division [GO:0051782]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; oxygen transport [GO:0015671]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA methylation [GO:1905643]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of metanephric cap mesenchymal cell proliferation [GO:0090096]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of telomerase activity [GO:0051973]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein-DNA complex disassembly [GO:0032986]; regulation of gene expression [GO:0010468]; regulation of somatic stem cell population maintenance [GO:1904672]; regulation of telomere maintenance [GO:0032204]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to gamma radiation [GO:0010332]; response to growth factor [GO:0070848]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein dimerization activity [GO:0046983]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription corepressor activity [GO:0003714]	activating transcription factor binding [GO:0033613]; core promoter binding [GO:0001047]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; E-box binding [GO:0070888]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1nlwd__d5i4zb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein dimerization activity [GO:0046983]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription corepressor activity [GO:0003714]; negative regulation of transcription by RNA polymerase II [GO:0000122]	cell [GO:0005623]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; activating transcription factor binding [GO:0033613]; core promoter binding [GO:0001047]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; E-box binding [GO:0070888]; protein dimerization activity [GO:0046983]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; beta-catenin-TCF complex assembly [GO:1904837]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular iron ion homeostasis [GO:0006879]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to hypoxia [GO:0071456]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; chromosome organization [GO:0051276]; cytokine-mediated signaling pathway [GO:0019221]; energy reserve metabolic process [GO:0006112]; ERK1 and ERK2 cascade [GO:0070371]; fibroblast apoptotic process [GO:0044346]; G1/S transition of mitotic cell cycle [GO:0000082]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell division [GO:0051782]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; oxygen transport [GO:0015671]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA methylation [GO:1905643]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of metanephric cap mesenchymal cell proliferation [GO:0090096]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of telomerase activity [GO:0051973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein-DNA complex disassembly [GO:0032986]; regulation of gene expression [GO:0010468]; regulation of somatic stem cell population maintenance [GO:1904672]; regulation of telomere maintenance [GO:0032204]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to gamma radiation [GO:0010332]; response to growth factor [GO:0070848]	negative regulation of transcription by RNA polymerase II [GO:0000122]	beta-catenin-TCF complex assembly [GO:1904837]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular iron ion homeostasis [GO:0006879]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to hypoxia [GO:0071456]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; chromosome organization [GO:0051276]; cytokine-mediated signaling pathway [GO:0019221]; energy reserve metabolic process [GO:0006112]; ERK1 and ERK2 cascade [GO:0070371]; fibroblast apoptotic process [GO:0044346]; G1/S transition of mitotic cell cycle [GO:0000082]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell division [GO:0051782]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; oxygen transport [GO:0015671]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA methylation [GO:1905643]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of metanephric cap mesenchymal cell proliferation [GO:0090096]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of telomerase activity [GO:0051973]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein-DNA complex disassembly [GO:0032986]; regulation of gene expression [GO:0010468]; regulation of somatic stem cell population maintenance [GO:1904672]; regulation of telomere maintenance [GO:0032204]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to gamma radiation [GO:0010332]; response to growth factor [GO:0070848]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein dimerization activity [GO:0046983]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription corepressor activity [GO:0003714]	activating transcription factor binding [GO:0033613]; core promoter binding [GO:0001047]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; E-box binding [GO:0070888]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1nm1a2_d1hkca2__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1nm3a1_d2rlia1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]	cell [GO:0005623]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; copper ion binding [GO:0005507]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; eye development [GO:0001654]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]	cell redox homeostasis [GO:0045454]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; eye development [GO:0001654]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; myofibril [GO:0030016]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin peroxidase activity [GO:0008379]	copper ion binding [GO:0005507]; protein disulfide oxidoreductase activity [GO:0015035]
d1nm3b1_d1erva___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin peroxidase activity [GO:0008379]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d1nm3b1_d1t3ba1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]	periplasmic space [GO:0042597]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]		cell [GO:0005623]; cytoplasm [GO:0005737]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin peroxidase activity [GO:0008379]	
d1nm5c__d4bvha___1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]	enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1nm9a1_d1cgxa3__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1nmah__d1i9rm2__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]; activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]
d1nmah__d3zhkb1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1nmal__d1ncch1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1nmal__d2bvqa1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1nmbh1_d2e7ba1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]
d1nmbn__d4gzwb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1nmcb1_d1uqsb1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1nmch1_d1nsnh2__1			Negarnaviricota	Firmicutes	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; membrane [GO:0016020]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1nmcl__d4ma1l2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	
d1nmdg__d3ffnb3__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1nmdg__d3fg6f3__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]
d1nmga__d4a75c___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]	nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]			cytoplasm [GO:0005737]; nucleoid [GO:0009295]		DNA binding [GO:0003677]	nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]
d1nmia__d1ezvd1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d1nmma__d1lyfa___1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	host cell cytoplasm [GO:0030430]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	lysozyme activity [GO:0003796]
d1nmmb__d1jnad___1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]		alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	
d1nmmc__d1l61a___1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	host cell cytoplasm [GO:0030430]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	lysozyme activity [GO:0003796]
d1nmua1_d1f9ba2__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	extracellular space [GO:0005615]; specific granule [GO:0042581]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d1nmud__d2qexf1__1			Proteobacteria	Euryarchaeota	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	translation [GO:0006412]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ribosome [GO:0005840]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1nmza__d2uz3d1__1	Metazoa		Chordata	Tenericutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627]; thymidine biosynthetic process [GO:0046105]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; thymidine kinase activity [GO:0004797]; zinc ion binding [GO:0008270]; DNA biosynthetic process [GO:0071897]	cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627]; thymidine biosynthetic process [GO:0046105]	DNA biosynthetic process [GO:0071897]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	ATP binding [GO:0005524]; thymidine kinase activity [GO:0004797]; zinc ion binding [GO:0008270]
d1nn0a__d1m1ye___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627]; thymidine biosynthetic process [GO:0046105]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627]; thymidine biosynthetic process [GO:0046105]	nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1nn1a__d1lvga___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627]; thymidine biosynthetic process [GO:0046105]	cytosol [GO:0005829]; photoreceptor inner segment [GO:0001917]; ATP binding [GO:0005524]; guanylate kinase activity [GO:0004385]; ATP metabolic process [GO:0046034]; dATP metabolic process [GO:0046060]; dGDP biosynthetic process [GO:0006185]; dGMP metabolic process [GO:0046054]; GDP biosynthetic process [GO:0046711]; GDP-mannose metabolic process [GO:0019673]; glycoprotein transport [GO:0034436]; GMP metabolic process [GO:0046037]; nucleotide phosphorylation [GO:0046939]; purine nucleotide metabolic process [GO:0006163]; xenobiotic metabolic process [GO:0006805]	cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627]; thymidine biosynthetic process [GO:0046105]	ATP metabolic process [GO:0046034]; dATP metabolic process [GO:0046060]; dGDP biosynthetic process [GO:0006185]; dGMP metabolic process [GO:0046054]; GDP biosynthetic process [GO:0046711]; GDP-mannose metabolic process [GO:0019673]; glycoprotein transport [GO:0034436]; GMP metabolic process [GO:0046037]; nucleotide phosphorylation [GO:0046939]; purine nucleotide metabolic process [GO:0006163]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytosol [GO:0005829]; photoreceptor inner segment [GO:0001917]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	ATP binding [GO:0005524]; guanylate kinase activity [GO:0004385]
d1nnaa__d4yw2a2__1			Negarnaviricota	Firmicutes	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1nnea1_d1w7ab1__1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; mismatched DNA binding [GO:0030983]; mismatch repair [GO:0006298]	cytosol [GO:0005829]; mismatch repair complex [GO:0032300]; adenine/cytosine mispair binding [GO:0032136]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA-dependent ATPase activity [GO:0008094]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]; cellular response to DNA damage stimulus [GO:0006974]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	mismatch repair [GO:0006298]	cellular response to DNA damage stimulus [GO:0006974]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]		cytosol [GO:0005829]; mismatch repair complex [GO:0032300]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; mismatched DNA binding [GO:0030983]	adenine/cytosine mispair binding [GO:0032136]; ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA-dependent ATPase activity [GO:0008094]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]
d1nnfa__d1gv8a___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	periplasmic space [GO:0042597]	extracellular space [GO:0005615]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1nnfa__d5h8sc1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]	metal ion binding [GO:0046872]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1nnga__d3az8s___1				Apicomplexa		hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]
d1nnha__d4p3ob1__1			Euryarchaeota	Proteobacteria	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	tRNA aminoacylation for protein translation [GO:0006418]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1nnob1_d2a06q1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	periplasmic space [GO:0042597]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1nnob2_d1aoma1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1nnpb__d4mmpa1__1	Metazoa		Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d1nnqa1_d1xu3b___1			Euryarchaeota	Proteobacteria	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]		cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]			iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1nnu.1_d1bmdb1__1			Apicomplexa	Deinococcus-Thermus	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	fatty acid biosynthetic process [GO:0006633]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]			enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; nucleotide binding [GO:0000166]	L-malate dehydrogenase activity [GO:0030060]
d1nnwb__d4mp0a1__1		Metazoa	Euryarchaeota	Chordata		cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]		cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]
d1no0a__d5givf___1				Deinococcus-Thermus		metal ion binding [GO:0046872]; metallocarboxypeptidase activity [GO:0004181]						metal ion binding [GO:0046872]; metallocarboxypeptidase activity [GO:0004181]
d1noba__d1zrua1__1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]		
d1nobc__d3u6xd2__1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]		
d1nobd__d2oj6f1__1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	viral outer capsid [GO:0039624]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	viral outer capsid [GO:0039624]		
d1nobe__d1noba___1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]		
d1nobf__d3qnda___1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	viral capsid [GO:0019028]		metal ion binding [GO:0046872]
d1nofa2_d4hpgc___1		Viridiplantae	Proteobacteria	Streptophyta	glucosylceramidase activity [GO:0004348]; sphingolipid metabolic process [GO:0006665]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	sphingolipid metabolic process [GO:0006665]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			glucosylceramidase activity [GO:0004348]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1noic__d2bisc___1	Metazoa		Chordata	Euryarchaeota	skeletal muscle myofibril [GO:0098723]; glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]; glycogen metabolic process [GO:0005977]	glycogen (starch) synthase activity [GO:0004373]; nucleotide binding [GO:0000166]	glycogen metabolic process [GO:0005977]		skeletal muscle myofibril [GO:0098723]		glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]	glycogen (starch) synthase activity [GO:0004373]; nucleotide binding [GO:0000166]
d1nooa__d5y5ib___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1np0.3_d1jaka1__1	Metazoa		Chordata	Actinobacteria	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	carbohydrate metabolic process [GO:0005975]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]		acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	beta-N-acetylhexosaminidase activity [GO:0004563]
d1np0.3_d3scvb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	carbohydrate metabolic process [GO:0005975]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	extracellular region [GO:0005576]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d1np0.4_d1cgva4__1	Metazoa		Chordata	Firmicutes	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	carbohydrate metabolic process [GO:0005975]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	extracellular region [GO:0005576]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1np1a__d2fs6b___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	vasodilation [GO:0042311]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	extracellular region [GO:0005576]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1np1b__d1adla___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	vasodilation [GO:0042311]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1np2a__d1jz7c5__1			Deinococcus-Thermus	Proteobacteria	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1np2b__d1yq2b5__1			Deinococcus-Thermus	Actinobacteria	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]		beta-galactosidase complex [GO:0009341]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1np2b__d4ha3a___1			Deinococcus-Thermus	Crenarchaeota	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-galactosidase activity [GO:0004565]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	beta-galactosidase activity [GO:0004565]; metal ion binding [GO:0046872]
d1np3a1_d5uaxb2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1np3a2_d4l76e1__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	potassium ion transport [GO:0006813]	cytosol [GO:0005829]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1np3b2_d1m76b2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d1np3b2_d4ro0a1__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	potassium ion transport [GO:0006813]	cytosol [GO:0005829]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1np3c1_d4xiyd2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytosol [GO:0005829]		ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]
d1np3d2_d1f0yb2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d1np4a__d2f73a1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	vasodilation [GO:0042311]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]
d1np4a__d3cbcc___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	vasodilation [GO:0042311]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1np8b__d4phjb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; proteolysis [GO:0006508]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	proteolysis [GO:0006508]	cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d1npaa__d3t7xa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1npba__d2a4wb2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; metal ion binding [GO:0046872]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]; metal ion binding [GO:0046872]	
d1npbf__d2p7lc___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; metal ion binding [GO:0046872]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1npca__d3ls7a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1npga__d1k0ya___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1npjb2_d2nrda2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1npjc1_d3t6va2__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1npjc2_d5x31a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1npla__d5d5gb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]	metal ion binding [GO:0046872]
d1npna1_d2ppaa1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1npna2_d1jxfa___1			Proteobacteria	Cyanobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	thylakoid membrane [GO:0042651]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1npnb1_d3qjtb2__1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1npnb2_d1mzzc2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1npnc1_d2fqea2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d1npnc2_d1ilud___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1npsa__d2m3ua1__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; sporulation resulting in formation of a cellular spore [GO:0030435]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	sporulation resulting in formation of a cellular spore [GO:0030435]	lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]			metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d1npua__d4ww2b1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of T cell apoptotic process [GO:0070234]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of T cell apoptotic process [GO:0070234]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1npvb__d1n49b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1npvb__d1uh9a___1		Fungi		Mucoromycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1npxa3_d2gh5a3__1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; flavin adenine dinucleotide binding [GO:0050660]; NADH peroxidase activity [GO:0016692]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; NADH peroxidase activity [GO:0016692]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]
d1npya2_d5gudc1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1npyb2_d1b26d2__1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d1npyd2_d2hk8b1__1			Proteobacteria	Aquificae	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]	cytosol [GO:0005829]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1npyd2_d2yfga1__1			Proteobacteria		cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	
d1npza__d2etlb___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; adult walking behavior [GO:0007628]; axon target recognition [GO:0007412]; axonal transport of mitochondrion [GO:0019896]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	adult walking behavior [GO:0007628]; axonal transport of mitochondrion [GO:0019896]; axon target recognition [GO:0007412]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]
d1npzb__d1e2te___1	Metazoa		Chordata	Proteobacteria	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	cytoplasm [GO:0005737]; arylamine N-acetyltransferase activity [GO:0004060]; N-hydroxyarylamine O-acetyltransferase activity [GO:0046990]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	arylamine N-acetyltransferase activity [GO:0004060]; N-hydroxyarylamine O-acetyltransferase activity [GO:0046990]
d1nq3c__d1j7hb___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; nucleus [GO:0005634]; peroxisome [GO:0005777]; deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; mRNA binding [GO:0003729]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]	cytosol [GO:0005829]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]	organonitrogen compound catabolic process [GO:1901565]	mitochondrial matrix [GO:0005759]; nucleus [GO:0005634]; peroxisome [GO:0005777]	cytosol [GO:0005829]	deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; mRNA binding [GO:0003729]	deaminase activity [GO:0019239]
d1nqap2_d1t4dc2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; cellular response to DNA damage stimulus [GO:0006974]; diaminopimelate biosynthetic process [GO:0019877]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	'de novo' L-methionine biosynthetic process [GO:0071266]; cellular response to DNA damage stimulus [GO:0006974]; diaminopimelate biosynthetic process [GO:0019877]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]
d1nqar2_d3q1lc2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]
d1nqba2_d4lvea___1		Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d1nqba2_d5j89b1__1		Metazoa		Chordata		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		
d1nqbc1_d2fbjh2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1nqjb__d2xh6b2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]; collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]	toxin activity [GO:0090729]
d1nqla1_d4aw4c1__1	Metazoa		Chordata	Firmicutes	clathrin-coated vesicle membrane [GO:0030665]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; receptor complex [GO:0043235]; calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; growth factor activity [GO:0008083]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; canonical Wnt signaling pathway [GO:0060070]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; ERK1 and ERK2 cascade [GO:0070371]; mammary gland alveolus development [GO:0060749]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of secretion [GO:0051048]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet degranulation [GO:0002576]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of gene expression [GO:0010628]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of calcium ion import [GO:0090279]; regulation of cell motility [GO:2000145]; regulation of protein localization to cell surface [GO:2000008]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; canonical Wnt signaling pathway [GO:0060070]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; ERK1 and ERK2 cascade [GO:0070371]; mammary gland alveolus development [GO:0060749]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of secretion [GO:0051048]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet degranulation [GO:0002576]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of gene expression [GO:0010628]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of calcium ion import [GO:0090279]; regulation of cell motility [GO:2000145]; regulation of protein localization to cell surface [GO:2000008]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; signal transduction [GO:0007165]	pathogenesis [GO:0009405]	clathrin-coated vesicle membrane [GO:0030665]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; receptor complex [GO:0043235]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; growth factor activity [GO:0008083]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]	heparin binding [GO:0008201]; lipid binding [GO:0008289]
d1nqmb__d4bj8e___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1nqmd__d2fhla1__1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1nqoo2_d3dbvr2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1nqoq2_d1gypb2__1			Firmicutes		cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	glycosome [GO:0020015]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1nqpd__d1ns6b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1nqtb2_d4fcca1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1nqtd2_d1bxga2__1	Metazoa		Chordata	Actinobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d1nqte1_d1nvtb1__1	Metazoa		Chordata	Euryarchaeota	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1nqte1_d4r1sb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cinnamoyl-CoA reductase activity [GO:0016621]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	cinnamoyl-CoA reductase activity [GO:0016621]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]
d1nqtg1_d3mw9a1__1	Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	
d1nqtg2_d3aogk1__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1nqti1_d1bw9a1__1	Metazoa		Chordata	Actinobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d1nqti1_d4mdha1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytosol [GO:0005829]; L-malate dehydrogenase activity [GO:0030060]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	L-malate dehydrogenase activity [GO:0030060]; NAD binding [GO:0051287]
d1nqtk2_d4fccf1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1nqtl2_d1b26e2__1	Metazoa		Chordata	Thermotogae	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d1nqub__d4gefj___1			Aquificae		cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]		cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]		6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	
d1nqvc__d1c2yc___1		Viridiplantae	Aquificae	Streptophyta	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1nqvd__d1kz6c___1		Fungi	Aquificae	Ascomycota	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]
d1nqve__d4gefe___1			Aquificae		cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]		cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]		6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	
d1nqwc__d1c2yd___1		Viridiplantae	Aquificae	Streptophyta	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1nqwe__d1rvvt___1			Aquificae	Firmicutes	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1nqxb__d4j07b___1			Aquificae	Actinobacteria	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1nr0a2_d1b9xa___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	actomyosin, actin portion [GO:0042643]; cortical actin cytoskeleton [GO:0030864]; myofibril [GO:0030016]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin filament depolymerization [GO:0030042]; locomotion [GO:0040011]; muscle thin filament assembly [GO:0071689]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of actin filament depolymerization [GO:0030836]; regulation of locomotion [GO:0040012]; sarcomere organization [GO:0045214]; skeletal muscle thin filament assembly [GO:0030240]	heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; photoreceptor disc membrane [GO:0097381]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]	actin filament depolymerization [GO:0030042]; locomotion [GO:0040011]; muscle thin filament assembly [GO:0071689]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of actin filament depolymerization [GO:0030836]; regulation of locomotion [GO:0040012]; sarcomere organization [GO:0045214]; skeletal muscle thin filament assembly [GO:0030240]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]	actomyosin, actin portion [GO:0042643]; cortical actin cytoskeleton [GO:0030864]; myofibril [GO:0030016]; sarcoplasm [GO:0016528]	heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; photoreceptor disc membrane [GO:0097381]	actin binding [GO:0003779]; actin filament binding [GO:0051015]	
d1nr1a1_d1o0sb1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	mitochondrial matrix [GO:0005759]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]
d1nr1a2_d1gz3c2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]; malate metabolic process [GO:0006108]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031]; tricarboxylic acid cycle [GO:0006099]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	malate metabolic process [GO:0006108]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]
d1nr1b1_d4rf2a___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1nr1b2_d2yfhc1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	glutamate biosynthetic process [GO:0006537]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]
d1nr1c2_d2yfgb1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	
d1nr1d1_d1udaa___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]; carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]
d1nr1d2_d2yfge1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	
d1nr1e2_d4omua1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1nr4f__d5ekib___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR4 chemokine receptor binding [GO:0031729]; chemokine activity [GO:0008009]; signaling receptor binding [GO:0005102]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; multicellular organism development [GO:0007275]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil chemotaxis [GO:0030593]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR7 chemokine receptor binding [GO:0031732]; chemokine activity [GO:0008009]; chemokine receptor binding [GO:0042379]; activation of GTPase activity [GO:0090630]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell chemotaxis [GO:0060326]; cell maturation [GO:0048469]; cell-cell signaling [GO:0007267]; cellular response to chemokine [GO:1990869]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine (C-C motif) ligand 21 signaling pathway [GO:0038116]; chemokine-mediated signaling pathway [GO:0070098]; dendritic cell chemotaxis [GO:0002407]; dendritic cell dendrite assembly [GO:0097026]; establishment of T cell polarity [GO:0001768]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; immunological synapse formation [GO:0001771]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; lymphocyte chemotaxis [GO:0048247]; mesangial cell-matrix adhesion [GO:0035759]; monocyte chemotaxis [GO:0002548]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of dendritic cell dendrite assembly [GO:2000548]; negative regulation of leukocyte tethering or rolling [GO:1903237]; neutrophil chemotaxis [GO:0030593]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell motility [GO:2000147]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of chemotaxis [GO:0050921]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of glycoprotein biosynthetic process [GO:0010560]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myeloid dendritic cell chemotaxis [GO:2000529]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of T cell migration [GO:2000406]; release of sequestered calcium ion into cytosol [GO:0051209]; response to prostaglandin E [GO:0034695]; ruffle organization [GO:0031529]; T cell costimulation [GO:0031295]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; multicellular organism development [GO:0007275]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil chemotaxis [GO:0030593]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	activation of GTPase activity [GO:0090630]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cell chemotaxis [GO:0060326]; cell maturation [GO:0048469]; cellular response to chemokine [GO:1990869]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine (C-C motif) ligand 21 signaling pathway [GO:0038116]; chemokine-mediated signaling pathway [GO:0070098]; dendritic cell chemotaxis [GO:0002407]; dendritic cell dendrite assembly [GO:0097026]; establishment of T cell polarity [GO:0001768]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; immunological synapse formation [GO:0001771]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; lymphocyte chemotaxis [GO:0048247]; mesangial cell-matrix adhesion [GO:0035759]; monocyte chemotaxis [GO:0002548]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of dendritic cell dendrite assembly [GO:2000548]; negative regulation of leukocyte tethering or rolling [GO:1903237]; neutrophil chemotaxis [GO:0030593]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell motility [GO:2000147]; positive regulation of chemotaxis [GO:0050921]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of glycoprotein biosynthetic process [GO:0010560]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myeloid dendritic cell chemotaxis [GO:2000529]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of T cell migration [GO:2000406]; release of sequestered calcium ion into cytosol [GO:0051209]; response to prostaglandin E [GO:0034695]; ruffle organization [GO:0031529]; T cell costimulation [GO:0031295]	extracellular space [GO:0005615]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	CCR4 chemokine receptor binding [GO:0031729]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; signaling receptor binding [GO:0005102]	CCR7 chemokine receptor binding [GO:0031732]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; chemokine receptor binding [GO:0042379]
d1nr7a2_d1nr1e2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]
d1nr7b2_d1hwxb3__1	Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	
d1nr7c2_d1hwxe3__1	Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	
d1nr7d2_d1bxgb2__1	Metazoa		Chordata	Actinobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d1nr7d2_d4a5oa1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytosol [GO:0005829]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]
d1nr7e1_d3ai2d___1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1nr7k1_d3etgf2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1nr7l2_d5guda1__1	Metazoa		Chordata	Actinobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1nrca__d2fhob1__1		Metazoa		Chordata		nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U12-type spliceosomal complex [GO:0005689]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; blastocyst formation [GO:0001825]; mRNA splicing, via spliceosome [GO:0000398]		blastocyst formation [GO:0001825]; mRNA splicing, via spliceosome [GO:0000398]		nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U12-type spliceosomal complex [GO:0005689]		mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1nro.1_d3u1jb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]
d1nrq.1_d3zvba1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ns1b__d3m8ai___1			Negarnaviricota	Negarnaviricota	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; modulation by symbiont of host intracellular transport [GO:0052038]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host innate immune response [GO:0052170]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; RNA binding [GO:0003723]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	modulation by symbiont of host intracellular transport [GO:0052038]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host innate immune response [GO:0052170]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]	RNA binding [GO:0003723]
d1ns1b__d5h5nb___1			Negarnaviricota	Negarnaviricota	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; modulation by symbiont of host intracellular transport [GO:0052038]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host innate immune response [GO:0052170]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; RNA binding [GO:0003723]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	modulation by symbiont of host intracellular transport [GO:0052038]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host innate immune response [GO:0052170]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]	RNA binding [GO:0003723]
d1ns2b1_d1jz8b4__1			Firmicutes	Proteobacteria	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1ns3.2_d5qcma___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d1ns4a1_d1jz6a4__1			Firmicutes	Proteobacteria	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1ns4a1_d1nszb1__1			Firmicutes	Firmicutes	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]			aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1ns4b1_d1jz2b4__1			Firmicutes	Proteobacteria	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1ns8a1_d1nsub1__1			Firmicutes	Firmicutes	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]			aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1ns8a1_d1yq2e4__1			Firmicutes	Actinobacteria	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	galactose metabolic process [GO:0006012]	carbohydrate metabolic process [GO:0005975]		beta-galactosidase complex [GO:0009341]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1ns8b1_d1nsma1__1			Firmicutes	Firmicutes	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]			aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1ns9a__d3ic0c___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1nsaa1_d1heee___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1nsaa2_d1pyta___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1nsca__d4ks2a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1nsga__d2f4ea___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; calmodulin binding [GO:0005516]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; auxin-activated signaling pathway [GO:0009734]; leaf development [GO:0048366]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	auxin-activated signaling pathway [GO:0009734]; leaf development [GO:0048366]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	calmodulin binding [GO:0005516]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1nsha__d2ggzb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of cell population proliferation [GO:0042127]	photoreceptor disc membrane [GO:0097381]; calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; signal transduction [GO:0007165]; visual perception [GO:0007601]	regulation of cell population proliferation [GO:0042127]	regulation of rhodopsin mediated signaling pathway [GO:0022400]; signal transduction [GO:0007165]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	photoreceptor disc membrane [GO:0097381]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048]
d1nsha__d4xjkf___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of cell population proliferation [GO:0042127]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	regulation of cell population proliferation [GO:0042127]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1nshb__d1tn4a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of cell population proliferation [GO:0042127]	calcium ion binding [GO:0005509]; troponin T binding [GO:0031014]	regulation of cell population proliferation [GO:0042127]		cytoplasm [GO:0005737]; nucleus [GO:0005634]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; troponin T binding [GO:0031014]
d1nsib__d5g6ma___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; arginine binding [GO:0034618]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin binding [GO:0034617]; arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; circadian rhythm [GO:0007623]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of leukocyte mediated cytotoxicity [GO:0001912]; prostaglandin secretion [GO:0032310]; protein targeting to peroxisome [GO:0006625]; regulation of cell population proliferation [GO:0042127]; regulation of cellular respiration [GO:0043457]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric-oxide synthase activity [GO:0004517]; nitric oxide biosynthetic process [GO:0006809]	arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; circadian rhythm [GO:0007623]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of leukocyte mediated cytotoxicity [GO:0001912]; prostaglandin secretion [GO:0032310]; protein targeting to peroxisome [GO:0006625]; regulation of cell population proliferation [GO:0042127]; regulation of cellular respiration [GO:0043457]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	nitric oxide biosynthetic process [GO:0006809]	cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]		arginine binding [GO:0034618]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin binding [GO:0034617]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric-oxide synthase activity [GO:0004517]
d1nskn__d3ngtm___1	Metazoa		Chordata		cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d1nskt__d4s0md___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1nsmb1_d1so0d___1		Metazoa	Firmicutes	Chordata	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	galactose metabolic process [GO:0006012]	galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1nsmb1_d3dx3a3__1		Metazoa	Firmicutes	Arthropoda	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	galactose metabolic process [GO:0006012]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1nsnh1_d2bx5k___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]				extracellular region [GO:0005576]; membrane [GO:0016020]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	
d1nsnl2_d1g7ja___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; membrane [GO:0016020]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1nsoa__d3qrob___1					viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral nucleocapsid [GO:0019013]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1nssa1_d1mn0b1__1			Firmicutes	Firmicutes	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]			aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1nssb1_d1hm3a3__1			Firmicutes	Bacteroidetes	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	galactose metabolic process [GO:0006012]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; chondroitin AC lyase activity [GO:0030341]; metal ion binding [GO:0046872]
d1nsva1_d1nsrb1__1			Firmicutes	Firmicutes	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]			aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1nsva1_d2qlya1__1		Metazoa	Firmicutes	Chordata	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	galactose metabolic process [GO:0006012]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]		apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]
d1nswa__d2v32b___1		Metazoa	Firmicutes	Annelida	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	protein disulfide oxidoreductase activity [GO:0015035]	peroxiredoxin activity [GO:0051920]
d1nswb__d1tk8b___1			Firmicutes	Proteobacteria	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1nsxa1_d1nssb1__1			Firmicutes	Firmicutes	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]			aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1nsxb1_d1mmub1__1			Firmicutes	Firmicutes	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]	galactose metabolic process [GO:0006012]			aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1nsya__d2e18a___1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]; NAD biosynthetic process [GO:0009435]; sporulation resulting in formation of a cellular spore [GO:0030435]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; double-stranded DNA binding [GO:0003690]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]; DNA topological change [GO:0006265]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; sporulation resulting in formation of a cellular spore [GO:0030435]	DNA topological change [GO:0006265]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]	ATP binding [GO:0005524]; double-stranded DNA binding [GO:0003690]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]
d1nsza1_d1xsif2__1			Firmicutes	Proteobacteria	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	galactose metabolic process [GO:0006012]	carbohydrate metabolic process [GO:0005975]			aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1nt2a__d2fyta1__1		Metazoa	Euryarchaeota	Chordata	methyltransferase activity [GO:0008168]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]; nucleic acid binding [GO:0003676]; protein-arginine N-methyltransferase activity [GO:0016274]; ribosome binding [GO:0043022]; negative regulation of protein ubiquitination [GO:0031397]; protein methylation [GO:0006479]	rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	negative regulation of protein ubiquitination [GO:0031397]; protein methylation [GO:0006479]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	methyltransferase activity [GO:0008168]; RNA binding [GO:0003723]	metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]; nucleic acid binding [GO:0003676]; protein-arginine N-methyltransferase activity [GO:0016274]; ribosome binding [GO:0043022]
d1nt4a__d5pgmd___1		Fungi	Proteobacteria	Ascomycota	outer membrane-bounded periplasmic space [GO:0030288]; 3-phytase activity [GO:0016158]; glucose-1-phosphatase activity [GO:0008877]; glucose catabolic process [GO:0006007]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glucose catabolic process [GO:0006007]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	outer membrane-bounded periplasmic space [GO:0030288]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	3-phytase activity [GO:0016158]; glucose-1-phosphatase activity [GO:0008877]	phosphoglycerate mutase activity [GO:0004619]
d1nt7a__d154la___1		Metazoa		Chordata		extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		extracellular region [GO:0005576]		lysozyme activity [GO:0003796]
d1nt7c__d201lb___1						host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]
d1nt7d__d4b2xc___1				Proteobacteria		glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]				glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1ntcb1_d3jrda___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphorelay response regulator activity [GO:0000156]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; nitrogen fixation [GO:0009399]; regulation of nitrogen utilization [GO:0006808]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasmic nucleosome [GO:0000787]; cytosol [GO:0005829]; invertasome [GO:0031421]; nucleoid [GO:0009295]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; protein homodimerization activity [GO:0042803]; sequence-specific DNA binding [GO:0043565]; sequence-specific DNA binding, bending [GO:0044374]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; bacterial transcription [GO:0001121]; chromatin organization involved in regulation of transcription [GO:0034401]; positive regulation of DNA recombination [GO:0045911]; provirus excision [GO:0032359]; regulation of transcription, DNA-templated [GO:0006355]; response to radiation [GO:0009314]	nitrogen fixation [GO:0009399]; regulation of nitrogen utilization [GO:0006808]; regulation of transcription, DNA-templated [GO:0006355]	bacterial transcription [GO:0001121]; chromatin organization involved in regulation of transcription [GO:0034401]; positive regulation of DNA recombination [GO:0045911]; provirus excision [GO:0032359]; regulation of transcription, DNA-templated [GO:0006355]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]	cytoplasmic nucleosome [GO:0000787]; cytosol [GO:0005829]; invertasome [GO:0031421]; nucleoid [GO:0009295]; protein-DNA complex [GO:0032993]	ATP binding [GO:0005524]; phosphorelay response regulator activity [GO:0000156]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; protein homodimerization activity [GO:0042803]; sequence-specific DNA binding [GO:0043565]; sequence-specific DNA binding, bending [GO:0044374]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1ntda1_d5waub2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1ntda2_d1jvol___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1ntgc1_d3nelb1__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nuclear body [GO:0016604]; ATP binding [GO:0005524]; interleukin-8 receptor binding [GO:0005153]; RNA binding [GO:0003723]; tRNA binding [GO:0000049]; tyrosine-tRNA ligase activity [GO:0004831]; apoptotic process [GO:0006915]; tRNA aminoacylation for protein translation [GO:0006418]; tyrosyl-tRNA aminoacylation [GO:0006437]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	apoptotic process [GO:0006915]; tRNA aminoacylation for protein translation [GO:0006418]; tyrosyl-tRNA aminoacylation [GO:0006437]	aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nuclear body [GO:0016604]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]	ATP binding [GO:0005524]; interleukin-8 receptor binding [GO:0005153]; RNA binding [GO:0003723]; tRNA binding [GO:0000049]; tyrosine-tRNA ligase activity [GO:0004831]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d1ntgd1_d3ersx1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nuclear body [GO:0016604]; ATP binding [GO:0005524]; interleukin-8 receptor binding [GO:0005153]; RNA binding [GO:0003723]; tRNA binding [GO:0000049]; tyrosine-tRNA ligase activity [GO:0004831]; apoptotic process [GO:0006915]; tRNA aminoacylation for protein translation [GO:0006418]; tyrosyl-tRNA aminoacylation [GO:0006437]	tRNA binding [GO:0000049]	apoptotic process [GO:0006915]; tRNA aminoacylation for protein translation [GO:0006418]; tyrosyl-tRNA aminoacylation [GO:0006437]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nuclear body [GO:0016604]		ATP binding [GO:0005524]; interleukin-8 receptor binding [GO:0005153]; RNA binding [GO:0003723]; tRNA binding [GO:0000049]; tyrosine-tRNA ligase activity [GO:0004831]	tRNA binding [GO:0000049]
d1ntia__d2wh5f___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]			endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]		fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]
d1ntkb1_d1hr7c1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1ntke1_d3foub___1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]
d1ntma1_d1sqbb1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1ntme1_d1eg9a1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	aromatic compound catabolic process [GO:0019439]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]
d1ntoe2_d5vl0d2__1		Metazoa	Crenarchaeota	Chordata	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1ntpa__d4mg3a___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ntza2_d2a06a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1ntza2_d3l72n2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1ntzb1_d3h1hn1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1ntzd1_d1gu2a___1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1nu1a1_d3h1jb2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1nu1a2_d3l75o1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1nu1b2_d3l75a2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1nu1e1_d1z02a1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d1nu2a__d1x05a1__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; postsynaptic density [GO:0014069]; phosphatidylinositol 3-kinase binding [GO:0043548]; phospholipid binding [GO:0005543]; SH2 domain binding [GO:0042169]; adult walking behavior [GO:0007628]; cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration [GO:0021813]; central nervous system development [GO:0007417]; cerebellum structural organization [GO:0021589]; cerebral cortex cell migration [GO:0021795]; cerebral cortex radially oriented cell migration [GO:0021799]; dendrite development [GO:0016358]; Golgi localization [GO:0051645]; hippocampus development [GO:0021766]; intracellular signal transduction [GO:0035556]; lateral motor column neuron migration [GO:0097477]; midgut development [GO:0007494]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein kinase activity [GO:0045860]; radial glia guided migration of Purkinje cell [GO:0021942]; response to drug [GO:0042493]; small GTPase mediated signal transduction [GO:0007264]; ventral spinal cord development [GO:0021517]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]; actin cytoskeleton reorganization [GO:0031532]; cell projection organization [GO:0030030]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G protein-coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin-activated receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904]	adult walking behavior [GO:0007628]; cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration [GO:0021813]; central nervous system development [GO:0007417]; cerebellum structural organization [GO:0021589]; cerebral cortex cell migration [GO:0021795]; cerebral cortex radially oriented cell migration [GO:0021799]; dendrite development [GO:0016358]; Golgi localization [GO:0051645]; hippocampus development [GO:0021766]; intracellular signal transduction [GO:0035556]; lateral motor column neuron migration [GO:0097477]; midgut development [GO:0007494]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein kinase activity [GO:0045860]; radial glia guided migration of Purkinje cell [GO:0021942]; response to drug [GO:0042493]; small GTPase mediated signal transduction [GO:0007264]; ventral spinal cord development [GO:0021517]	actin cytoskeleton reorganization [GO:0031532]; cell projection organization [GO:0030030]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G protein-coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin-activated receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904]	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; postsynaptic density [GO:0014069]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	phosphatidylinositol 3-kinase binding [GO:0043548]; phospholipid binding [GO:0005543]; SH2 domain binding [GO:0042169]	phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]
d1nu5a2_d3t6cb1__1			Proteobacteria	Proteobacteria	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; 2,4-dichlorophenoxyacetic acid catabolic process [GO:0046300]; cellular amino acid catabolic process [GO:0009063]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	2,4-dichlorophenoxyacetic acid catabolic process [GO:0046300]; cellular amino acid catabolic process [GO:0009063]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]
d1nu6b2_d1a88c___1	Metazoa		Chordata	Actinobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	chloride peroxidase activity [GO:0016691]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	chloride peroxidase activity [GO:0016691]
d1nu7d1_d1nu9f2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d1nu9d__d1c2ha___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1nu9d__d2q6gb___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1nuca__d3hzxa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1nudb2_d1vjjb8__1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]		cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]		calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]	
d1nuec__d5yole___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1nuee__d3ztsi___1	Metazoa		Chordata	Aquificae	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1nufa3_d1kv3d2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1nuga1_d1wzka1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]		calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1nugb1_d1jsya1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; acetylcholine receptor binding [GO:0033130]; AP-2 adaptor complex binding [GO:0035612]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein homodimerization activity [GO:0042803]; clathrin-dependent endocytosis [GO:0072583]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	clathrin-dependent endocytosis [GO:0072583]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]	acetylcholine receptor binding [GO:0033130]; AP-2 adaptor complex binding [GO:0035612]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein homodimerization activity [GO:0042803]
d1nugb2_d1fiea2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1nugb3_d1ggya3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1nugb4_d4guzd1__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	acetyltransferase activity [GO:0016407]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]		calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]	acetyltransferase activity [GO:0016407]
d1nuha__d2x3ye___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]
d1nuha__d3hjbc1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	cytosol [GO:0005829]; glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytosol [GO:0005829]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d1numa__d2k8ga1__1		Metazoa		Chordata		catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]		gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]		catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]		mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]
d1nvid__d1jsba1__1			Proteobacteria		cytosol [GO:0005829]; molybdopterin synthase activity [GO:0030366]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]		Mo-molybdopterin cofactor biosynthetic process [GO:0006777]		cytosol [GO:0005829]		molybdopterin synthase activity [GO:0030366]	
d1nvla__d2wh5c___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]			endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]		fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]
d1nvma2_d2qjip___1			Proteobacteria	Euryarchaeota	acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; aromatic compound catabolic process [GO:0019439]; phenol-containing compound catabolic process [GO:0019336]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; aromatic amino acid family biosynthetic process [GO:0009073]	aromatic compound catabolic process [GO:0019439]; phenol-containing compound catabolic process [GO:0019336]	aromatic amino acid family biosynthetic process [GO:0009073]			acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]
d1nvmb2_d1vm6b2__1			Proteobacteria	Thermotogae	acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; aromatic compound catabolic process [GO:0019439]; phenol-containing compound catabolic process [GO:0019336]	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aromatic compound catabolic process [GO:0019439]; phenol-containing compound catabolic process [GO:0019336]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytosol [GO:0005829]	acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]
d1nvmb2_d2gz3a2__1			Proteobacteria	Firmicutes	acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; aromatic compound catabolic process [GO:0019439]; phenol-containing compound catabolic process [GO:0019336]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	aromatic compound catabolic process [GO:0019439]; phenol-containing compound catabolic process [GO:0019336]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]			acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]
d1nvmc2_d1rqea2__1			Proteobacteria	Actinobacteria	acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; aromatic compound catabolic process [GO:0019439]; phenol-containing compound catabolic process [GO:0019336]	metal ion binding [GO:0046872]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]	aromatic compound catabolic process [GO:0019439]; phenol-containing compound catabolic process [GO:0019336]				acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	metal ion binding [GO:0046872]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]
d1nvmg2_d4s1ff1__1			Proteobacteria	Proteobacteria	acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; aromatic compound catabolic process [GO:0019439]; phenol-containing compound catabolic process [GO:0019336]	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	aromatic compound catabolic process [GO:0019439]; phenol-containing compound catabolic process [GO:0019336]	fructose metabolic process [GO:0006000]		cytoplasm [GO:0005737]	acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	fructose 6-phosphate aldolase activity [GO:0097023]
d1nvmh2_d4gpd42__1		Metazoa	Proteobacteria	Arthropoda	acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; aromatic compound catabolic process [GO:0019439]; phenol-containing compound catabolic process [GO:0019336]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	aromatic compound catabolic process [GO:0019439]; phenol-containing compound catabolic process [GO:0019336]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1nvpa2_d3cwad2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; male pronucleus [GO:0001940]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; transcriptional preinitiation complex [GO:0097550]; aryl hydrocarbon receptor binding [GO:0017162]; core promoter binding [GO:0001047]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; proximal promoter sequence-specific DNA binding [GO:0000987]; repressing transcription factor binding [GO:0070491]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II repressing transcription factor binding [GO:0001103]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIB-class transcription factor binding [GO:0001093]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; snRNA transcription by RNA polymerase II [GO:0042795]; spermatogenesis [GO:0007283]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; spermatogenesis [GO:0007283]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]; viral process [GO:0016032]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; male pronucleus [GO:0001940]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional preinitiation complex [GO:0097550]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	aryl hydrocarbon receptor binding [GO:0017162]; core promoter binding [GO:0001047]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; proximal promoter sequence-specific DNA binding [GO:0000987]; repressing transcription factor binding [GO:0070491]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II repressing transcription factor binding [GO:0001103]; TFIIB-class transcription factor binding [GO:0001093]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1nvta1_d1v3va2__1		Metazoa	Euryarchaeota	Chordata	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]; 13-prostaglandin reductase activity [GO:0036132]; 15-oxoprostaglandin 13-oxidase activity [GO:0047522]; 2-alkenal reductase [NAD(P)+] activity [GO:0032440]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]			cytoplasm [GO:0005737]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	13-prostaglandin reductase activity [GO:0036132]; 15-oxoprostaglandin 13-oxidase activity [GO:0047522]; 2-alkenal reductase [NAD(P)+] activity [GO:0032440]
d1nvtb1_d5ej2d___1			Euryarchaeota	Actinobacteria	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	(+)-trans-carveol dehydrogenase activity [GO:0033702]; nucleotide binding [GO:0000166]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]				NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	(+)-trans-carveol dehydrogenase activity [GO:0033702]; nucleotide binding [GO:0000166]
d1nvxr__d1d2eb3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1nw2b__d1x9mb___1			Firmicutes	Proteobacteria	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1nw2e__d2eiob___1			Firmicutes	Proteobacteria	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1nw2f__d1b8xa2__1		Metazoa	Firmicutes	Platyhelminthes	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]		protein disulfide oxidoreductase activity [GO:0015035]	glutathione transferase activity [GO:0004364]
d1nw2g__d1nswc___1			Firmicutes	Firmicutes	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]	cell [GO:0005623]	protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d1nw4b__d4txnd___1		Metazoa	Apicomplexa	Platyhelminthes	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]	nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]		cytoplasm [GO:0005737]	purine-nucleoside phosphorylase activity [GO:0004731]	uridine phosphorylase activity [GO:0004850]
d1nw4e__d5b7qa___1			Apicomplexa	Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]			purine-nucleoside phosphorylase activity [GO:0004731]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d1nwba__d2apna___1			Aquificae	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; structural molecule activity [GO:0005198]; iron-sulfur cluster assembly [GO:0016226]; protein maturation by iron-sulfur cluster transfer [GO:0097428]	cytosol [GO:0005829]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; structural molecule activity [GO:0005198]; iron-sulfur cluster assembly [GO:0016226]; protein maturation [GO:0051604]; protein maturation by [4Fe-4S] cluster transfer [GO:0106035]	iron-sulfur cluster assembly [GO:0016226]; protein maturation by iron-sulfur cluster transfer [GO:0097428]	iron-sulfur cluster assembly [GO:0016226]; protein maturation [GO:0051604]; protein maturation by [4Fe-4S] cluster transfer [GO:0106035]		cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; structural molecule activity [GO:0005198]	2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; structural molecule activity [GO:0005198]
d1nwda__d1wrla___1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	calcium-mediated signaling [GO:0019722]	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]		cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]
d1nwic__d1c0ha___1	Metazoa		Mollusca		cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1nwka2_d4h0oa2__1	Metazoa		Chordata		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]
d1nwna__d3wcwg___1	Metazoa	Metazoa	Mollusca	Annelida	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1nwoa__d5ue6i2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1nwpa__d1a4bb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1nwrc2_d2g8za2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; specific granule lumen [GO:0035580]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; extracellular matrix structural constituent [GO:0005201]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; neutrophil degranulation [GO:0043312]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; neutrophil degranulation [GO:0043312]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; extracellular matrix structural constituent [GO:0005201]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]
d1nwwa__d4xbye___1			Actinobacteria	Actinobacteria	limonene-1,2-epoxide hydrolase activity [GO:0018744]	limonene-1,2-epoxide hydrolase activity [GO:0018744]					limonene-1,2-epoxide hydrolase activity [GO:0018744]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d1nwza__d4h6ja___1		Metazoa	Proteobacteria	Chordata	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]; aryl hydrocarbon receptor binding [GO:0017162]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; nuclear receptor activity [GO:0004879]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; cell differentiation [GO:0030154]; embryonic placenta development [GO:0001892]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; xenobiotic metabolic process [GO:0006805]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cell differentiation [GO:0030154]; embryonic placenta development [GO:0001892]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	aryl hydrocarbon receptor binding [GO:0017162]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; nuclear receptor activity [GO:0004879]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]
d1nx0a__d2l0pa___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; calcium-dependent cysteine-type endopeptidase inhibitor activity [GO:0010859]; protease binding [GO:0002020]; inhibition of cysteine-type endopeptidase activity [GO:0097340]; protein catabolic process [GO:0030163]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	inhibition of cysteine-type endopeptidase activity [GO:0097340]; protein catabolic process [GO:0030163]	intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	calcium-dependent cysteine-type endopeptidase inhibitor activity [GO:0010859]; protease binding [GO:0002020]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]
d1nx0b__d4phka___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; calcium-dependent cysteine-type endopeptidase inhibitor activity [GO:0010859]; protease binding [GO:0002020]; inhibition of cysteine-type endopeptidase activity [GO:0097340]; protein catabolic process [GO:0030163]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	inhibition of cysteine-type endopeptidase activity [GO:0097340]; protein catabolic process [GO:0030163]	cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	calcium-dependent cysteine-type endopeptidase inhibitor activity [GO:0010859]; protease binding [GO:0002020]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d1nx0b__d5w1fh___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; calcium-dependent cysteine-type endopeptidase inhibitor activity [GO:0010859]; protease binding [GO:0002020]; inhibition of cysteine-type endopeptidase activity [GO:0097340]; protein catabolic process [GO:0030163]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	inhibition of cysteine-type endopeptidase activity [GO:0097340]; protein catabolic process [GO:0030163]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium-dependent cysteine-type endopeptidase inhibitor activity [GO:0010859]; protease binding [GO:0002020]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1nx1a__d1odbd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	proteolysis [GO:0006508]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d1nx1b__d1wrla___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; proteolysis [GO:0006508]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	proteolysis [GO:0006508]	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]
d1nx7a__d1icca___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	oxidation-reduction process [GO:0055114]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1nx9a2_d4dlnc1__1			Proteobacteria	Proteobacteria	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	hydrolase activity [GO:0016787]					alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	hydrolase activity [GO:0016787]
d1nxca__d1kreb___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]; N-glycan processing [GO:0006491]; protein glycosylation [GO:0006486]	extracellular region [GO:0005576]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]; protein glycosylation [GO:0006486]	N-glycan processing [GO:0006491]; protein glycosylation [GO:0006486]	protein glycosylation [GO:0006486]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; membrane [GO:0016020]	calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]	calcium ion binding [GO:0005509]; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]
d1nxd1__d5f9ta1__1	Viridiplantae		Streptophyta	Firmicutes	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1nxd2__d1fv3b1__1	Viridiplantae		Streptophyta	Firmicutes	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1nxd2__d2du0c___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1nxd3__d5ik4a2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]		animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]		basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	signaling receptor binding [GO:0005102]
d1nxea__d3l98a___1			Proteobacteria		cytosol [GO:0005829]; citrate (Si)-synthase activity [GO:0004108]; identical protein binding [GO:0042802]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]		citrate (Si)-synthase activity [GO:0004108]; identical protein binding [GO:0042802]	
d1nxfa__d3w4ud___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1nxgb__d2ifcd___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; citrate (Si)-synthase activity [GO:0004108]; identical protein binding [GO:0042802]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	citrate (Si)-synthase activity [GO:0004108]; identical protein binding [GO:0042802]	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]
d1nxma__d1vj2a___1			Firmicutes	Thermotogae	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	metal ion binding [GO:0046872]					dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	metal ion binding [GO:0046872]
d1nxmb__d4ewea___1		Metazoa	Firmicutes	Chordata	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; quercetin 2,3-dioxygenase activity [GO:0008127]; transcription coregulator activity [GO:0003712]; digestion [GO:0007586]; monocyte differentiation [GO:0030224]; transcription by RNA polymerase II [GO:0006366]		digestion [GO:0007586]; monocyte differentiation [GO:0030224]; transcription by RNA polymerase II [GO:0006366]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	metal ion binding [GO:0046872]; quercetin 2,3-dioxygenase activity [GO:0008127]; transcription coregulator activity [GO:0003712]
d1nxva__d1qo0e___1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	amide binding [GO:0033218]; kinase activity [GO:0016301]; amino acid transport [GO:0006865]; negative regulation of hydrolase activity [GO:0051346]; regulation of cellular amide catabolic process [GO:0034251]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	amino acid transport [GO:0006865]; negative regulation of hydrolase activity [GO:0051346]; regulation of cellular amide catabolic process [GO:0034251]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]	amide binding [GO:0033218]; kinase activity [GO:0016301]
d1ny6d__d1wp9a1__1			Aquificae	Euryarchaeota	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; DNA repair [GO:0006281]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	DNA repair [GO:0006281]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]
d1ny6e__d4ct5b2__1		Metazoa	Aquificae	Chordata	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]		cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]
d1ny6g__d2h1li___1		Metazoa	Aquificae	Chordata	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1ny6j__d1egab1__1			Aquificae	Proteobacteria	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; small ribosomal subunit rRNA binding [GO:0070181]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; small ribosomal subunit rRNA binding [GO:0070181]
d1ny6j__d2p65a___1			Aquificae	Apicomplexa	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	apicoplast [GO:0020011]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; protein metabolic process [GO:0019538]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	protein metabolic process [GO:0019538]		apicoplast [GO:0020011]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]
d1ny6k__d1s9ha1__1			Aquificae		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA replication [GO:0006260]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; suppression by virus of G2/M transition of host mitotic cell cycle [GO:0039592]; viral DNA genome replication [GO:0039693]; viral entry via permeabilization of inner membrane [GO:0099008]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	DNA replication [GO:0006260]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; suppression by virus of G2/M transition of host mitotic cell cycle [GO:0039592]; viral DNA genome replication [GO:0039693]; viral entry via permeabilization of inner membrane [GO:0099008]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]
d1ny6l__d1n25b___1			Aquificae		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]		host cell nucleus [GO:0042025]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]
d1ny721_d1yc6a___1					host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	transport of virus in host, cell to cell [GO:0046740]		host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1nycb1_d1smpi___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; pathogenesis [GO:0009405]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; pathogenesis [GO:0009405]; proteolysis [GO:0006508]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cysteine-type endopeptidase inhibitor activity [GO:0004869]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1nyeb__d4noza1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; hyperosmotic response [GO:0006972]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	response to oxidative stress [GO:0006979]	hyperosmotic response [GO:0006972]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	response to oxidative stress [GO:0006979]	cytosol [GO:0005829]		peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	
d1nyee1_d1lqle___1			Proteobacteria	Tenericutes	cytosol [GO:0005829]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; hyperosmotic response [GO:0006972]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]	hyperosmotic response [GO:0006972]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	peroxidase activity [GO:0004601]
d1nyqa3_d1wxob___1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	threonyl-tRNA aminoacylation [GO:0006435]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]	aminoacyl-tRNA editing activity [GO:0002161]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1nyqb4_d4dpgf2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]; activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	threonyl-tRNA aminoacylation [GO:0006435]	activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	cytoplasm [GO:0005737]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]	amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]
d1nyra1_d4ttvd2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	threonyl-tRNA aminoacylation [GO:0006435]	threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]
d1nyrb2_d5ee3b2__1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of response to salt stress [GO:1901001]; response to cadmium ion [GO:0046686]; response to salt stress [GO:0009651]	threonyl-tRNA aminoacylation [GO:0006435]	negative regulation of defense response to bacterium [GO:1900425]; negative regulation of response to salt stress [GO:1901001]; response to cadmium ion [GO:0046686]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]
d1nyta2_d1ch6f1__1			Proteobacteria		cytosol [GO:0005829]; NADP binding [GO:0050661]; nucleotide binding [GO:0000166]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]		NADP binding [GO:0050661]; nucleotide binding [GO:0000166]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	
d1nyta2_d1p74a2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; NADP binding [GO:0050661]; nucleotide binding [GO:0000166]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]	cytosol [GO:0005829]	NADP binding [GO:0050661]; nucleotide binding [GO:0000166]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1nytb2_d2hk7b1__1			Proteobacteria	Aquificae	cytosol [GO:0005829]; NADP binding [GO:0050661]; nucleotide binding [GO:0000166]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]	cytosol [GO:0005829]	NADP binding [GO:0050661]; nucleotide binding [GO:0000166]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1nytc2_d1nvtb2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; NADP binding [GO:0050661]; nucleotide binding [GO:0000166]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]		NADP binding [GO:0050661]; nucleotide binding [GO:0000166]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1nytd1_d2tmgf1__1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; NADP binding [GO:0050661]; nucleotide binding [GO:0000166]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]		NADP binding [GO:0050661]; nucleotide binding [GO:0000166]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d1nytd2_d3ngla1__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; NADP binding [GO:0050661]; nucleotide binding [GO:0000166]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]		NADP binding [GO:0050661]; nucleotide binding [GO:0000166]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]
d1nz7a__d1fpza___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cell cycle arrest [GO:0007050]; cilium assembly [GO:0060271]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell population proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cell cycle arrest [GO:0007050]; cilium assembly [GO:0060271]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell population proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1nzcb__d3elna___1		Metazoa	Firmicutes	Chordata	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]		cysteine metabolic process [GO:0006534]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]		cytosol [GO:0005829]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d1nzcc__d1oi6a___1			Firmicutes	Actinobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]					dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d1nzcc__d4aq6i___1			Firmicutes	Proteobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]		L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]		protein-DNA complex [GO:0032993]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1nzcd__d1y3ta1__1			Firmicutes	Firmicutes	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	metal ion binding [GO:0046872]; quercetin 2,3-dioxygenase activity [GO:0008127]					dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	metal ion binding [GO:0046872]; quercetin 2,3-dioxygenase activity [GO:0008127]
d1nzfa__d1m5ra___1					DNA beta-glucosyltransferase activity [GO:0033821]; DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]	DNA beta-glucosyltransferase activity [GO:0033821]; DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]	DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]	DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]			DNA beta-glucosyltransferase activity [GO:0033821]	DNA beta-glucosyltransferase activity [GO:0033821]
d1nzkb__d2kh2a___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d1nzkc__d2afgc___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1nzkc__d2p23b___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of bile acid biosynthetic process [GO:0070858]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of bile acid biosynthetic process [GO:0070858]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]
d1nzkd__d4q91a1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1nzlb__d3ov1a___1		Metazoa		Chordata	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]		aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]		cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]
d1nzq.1_d2bdin___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1nzrb__d4a2ha3__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1nzrc__d3paua2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d1nzrd__d2b08c2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1nzta4_d2iesb2__1				Aquificae		metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]		lipid A biosynthetic process [GO:0009245]				metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d1nzwb__d5vbfb___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]
d1nzwf__d4oe2d___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1nzxa__d2onpd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d1nzxa__d3ifgo1__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	
d1nzxe__d2onme___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d1nzxf__d4nmka___1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1nzxg__d4qgka1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; long-chain-alcohol oxidase activity [GO:0046577]; long-chain-aldehyde dehydrogenase activity [GO:0050061]; medium-chain-aldehyde dehydrogenase activity [GO:0052814]; protein homodimerization activity [GO:0042803]; cellular aldehyde metabolic process [GO:0006081]; central nervous system development [GO:0007417]; epidermis development [GO:0008544]; fatty acid alpha-oxidation [GO:0001561]; hexadecanal metabolic process [GO:0046458]; oxidation-reduction process [GO:0055114]; peripheral nervous system development [GO:0007422]; phytol metabolic process [GO:0033306]; sesquiterpenoid metabolic process [GO:0006714]; sphingolipid biosynthetic process [GO:0030148]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cellular aldehyde metabolic process [GO:0006081]; central nervous system development [GO:0007417]; epidermis development [GO:0008544]; fatty acid alpha-oxidation [GO:0001561]; hexadecanal metabolic process [GO:0046458]; oxidation-reduction process [GO:0055114]; peripheral nervous system development [GO:0007422]; phytol metabolic process [GO:0033306]; sesquiterpenoid metabolic process [GO:0006714]; sphingolipid biosynthetic process [GO:0030148]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; long-chain-alcohol oxidase activity [GO:0046577]; long-chain-aldehyde dehydrogenase activity [GO:0050061]; medium-chain-aldehyde dehydrogenase activity [GO:0052814]; protein homodimerization activity [GO:0042803]
d1nzza__d4i3va___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1nzzd__d2onpe___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d1nzzf__d3v9ka___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; identical protein binding [GO:0042802]; proline catabolic process to glutamate [GO:0010133]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	proline catabolic process to glutamate [GO:0010133]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; identical protein binding [GO:0042802]
d1nzzh__d3rhjd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]
d1o00a__d1ad3b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]
d1o00a__d2jg7c___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1o00b__d2onph___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d1o00b__d4npib___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1o00c__d4l2oa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]
d1o00f__d3ek1b___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; gamma-aminobutyric acid catabolic process [GO:0009450]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	gamma-aminobutyric acid catabolic process [GO:0009450]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]
d1o00h__d1bxsb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	cytosol [GO:0005829]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]
d1o01a__d5klmb___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1o01e__d3iwki___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]
d1o02c__d4qetd___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	
d1o02g__d2ej6a___1	Metazoa		Chordata	Deinococcus-Thermus	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1o04d__d4h73c___1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1o04e__d4ni4c___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	
d1o04h__d4gnzd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]
d1o05d__d4i3wb___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1o0ba2_d4mafg2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	nucleotide binding [GO:0000166]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; sulfate assimilation [GO:0000103]	glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	sulfate assimilation [GO:0000103]	cytosol [GO:0005829]		ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]	nucleotide binding [GO:0000166]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1o0ca2_d5o0aa___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	coenzyme A biosynthetic process [GO:0015937]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1o0pa__d3zzya___1	Metazoa	Metazoa	Chordata	Chordata	nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribosome [GO:0005840]; spliceosomal complex [GO:0005681]; identical protein binding [GO:0042802]; pre-mRNA branch point binding [GO:0045131]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270]; Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nuclear body organization [GO:0030575]; regulation of steroid biosynthetic process [GO:0050810]; spliceosomal complex assembly [GO:0000245]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nuclear body organization [GO:0030575]; regulation of steroid biosynthetic process [GO:0050810]; spliceosomal complex assembly [GO:0000245]	fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribosome [GO:0005840]; spliceosomal complex [GO:0005681]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; pre-mRNA branch point binding [GO:0045131]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270]	poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]
d1o0sa2_d1hrdc2__1	Metazoa		Nematoda (roundworms)	Firmicutes	mitochondrial matrix [GO:0005759]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]		cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	mitochondrial matrix [GO:0005759]		malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]	glutamate dehydrogenase (NAD+) activity [GO:0004352]
d1o0va1_d4p2cg___1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1o0va2_d3tnnb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1o0va3_d2j1kt___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1o0vb2_d3oj2c2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1o0wb1_d2nuga1__1			Thermotogae	Aquificae	cytoplasm [GO:0005737]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]; rRNA binding [GO:0019843]; mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]; mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]; rRNA binding [GO:0019843]	double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]
d1o16a__d4i0vc___1	Metazoa		Chordata		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1o17a1_d2wk5a1__1		Metazoa	Crenarchaeota	Chordata	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	tryptophan biosynthetic process [GO:0000162]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	cytosol [GO:0005829]	cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1o17b1_d2wk5d1__1		Metazoa	Crenarchaeota	Chordata	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	tryptophan biosynthetic process [GO:0000162]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	cytosol [GO:0005829]	cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1o1ha__d5xiab___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1o1ia__d5x2uf___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1o1ja2_d1b33e___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; photosynthesis [GO:0015979]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	photosynthesis [GO:0015979]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1o1kd__d2olpa___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1o1la1_d4h0me___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1o1md__d1hv4c___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1o1na2_d2d2mb___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1o1nb__d3wcth___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1o1od__d3wcub___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1o1pa2_d5v3tb___1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen transport [GO:0015671]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxygen transport [GO:0015671]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d1o1sa__d1kzpa___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1o1tb__d1gszc2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1o1va__d4oryg___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; lipid binding [GO:0008289]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; negative regulation of cell population proliferation [GO:0008285]; triglyceride catabolic process [GO:0019433]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; negative regulation of cell population proliferation [GO:0008285]; triglyceride catabolic process [GO:0019433]	cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	lipid binding [GO:0008289]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d1o1va__d4zcba___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; lipid binding [GO:0008289]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; negative regulation of cell population proliferation [GO:0008285]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; negative regulation of cell population proliferation [GO:0008285]; triglyceride catabolic process [GO:0019433]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	lipid binding [GO:0008289]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1o1wa1_d3o3ga___1				Thermotogae	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; ribonuclease H2 complex [GO:0032299]; manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; mismatch repair [GO:0006298]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA replication, removal of RNA primer [GO:0043137]; mismatch repair [GO:0006298]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; ribonuclease H2 complex [GO:0032299]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1o23a__d4nhta___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1o23c__d1ge0a___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1o2na__d3pmja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1o2oa__d3eaja___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1o2ra__d3snca___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1o2sa__d4prob___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d1o2sa__d8kme.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d1o2ya__d4cboa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1o31a__d1ylda___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	digestion [GO:0007586]; proteolysis [GO:0006508]	collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]
d1o36a__d1zlra___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d1o38a__d2pfea___1	Metazoa		Chordata	Actinobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d1o3aa__d3ensd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1o3ka__d1ep5b___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1o3la__d2uwpa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1o3p.1_d2m5ta___1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; viral capsid [GO:0019028]	serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1o3qa2_d2bgci2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; pathogenesis [GO:0009405]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	pathogenesis [GO:0009405]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1o3ta1_d2csoa1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]; actin cytoskeleton reorganization [GO:0031532]; cell projection organization [GO:0030030]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G protein-coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin-activated receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	actin cytoskeleton reorganization [GO:0031532]; cell projection organization [GO:0030030]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G protein-coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin-activated receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]
d1o3wa__d2h4ca___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; inflammatory response [GO:0006954]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	arachidonic acid secretion [GO:0050482]; inflammatory response [GO:0006954]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1o46a__d2huwb___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]
d1o47a__d4d8ka2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]
d1o4aa__d1aotf___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	actin filament [GO:0005884]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome [GO:0005768]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glial cell projection [GO:0097386]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum [GO:0097038]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; Schaffer collateral - CA1 synapse [GO:0098685]; alpha-tubulin binding [GO:0043014]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; growth factor receptor binding [GO:0070851]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; axon guidance [GO:0007411]; blood coagulation [GO:0007596]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cellular response to amyloid-beta [GO:1904646]; cellular response to glycine [GO:1905430]; cellular response to L-glutamate [GO:1905232]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cytokine-mediated signaling pathway [GO:0019221]; dendrite morphogenesis [GO:0048813]; dendritic spine maintenance [GO:0097062]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ephrin receptor signaling pathway [GO:0048013]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; feeding behavior [GO:0007631]; forebrain development [GO:0030900]; heart process [GO:0003015]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide biosynthetic process [GO:0010730]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to membrane [GO:1905477]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein phosphorylation [GO:0006468]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; response to amyloid-beta [GO:1904645]; response to ethanol [GO:0045471]; response to hydrogen peroxide [GO:0042542]; response to singlet oxygen [GO:0000304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; axon guidance [GO:0007411]; blood coagulation [GO:0007596]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cellular response to amyloid-beta [GO:1904646]; cellular response to glycine [GO:1905430]; cellular response to L-glutamate [GO:1905232]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cytokine-mediated signaling pathway [GO:0019221]; dendrite morphogenesis [GO:0048813]; dendritic spine maintenance [GO:0097062]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ephrin receptor signaling pathway [GO:0048013]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; feeding behavior [GO:0007631]; forebrain development [GO:0030900]; heart process [GO:0003015]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide biosynthetic process [GO:0010730]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to membrane [GO:1905477]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein phosphorylation [GO:0006468]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; response to amyloid-beta [GO:1904645]; response to ethanol [GO:0045471]; response to hydrogen peroxide [GO:0042542]; response to singlet oxygen [GO:0000304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	actin filament [GO:0005884]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome [GO:0005768]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glial cell projection [GO:0097386]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum [GO:0097038]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; Schaffer collateral - CA1 synapse [GO:0098685]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]	alpha-tubulin binding [GO:0043014]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; growth factor receptor binding [GO:0070851]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; T cell receptor binding [GO:0042608]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d1o4ja__d4ohda1__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]; abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]	cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]
d1o4pa__d1ka6a___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; innate immune response [GO:0045087]; lymphocyte activation [GO:0046649]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative regulation of CD40 signaling pathway [GO:2000349]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; phagocytosis [GO:0006909]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; innate immune response [GO:0045087]; lymphocyte activation [GO:0046649]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative regulation of CD40 signaling pathway [GO:2000349]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; phagocytosis [GO:0006909]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]
d1o4ub2_d2b7nc1__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1o4va__d4ay3c___1			Thermotogae	Firmicutes	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]
d1o4va__d4z7ja___1			Thermotogae	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d1o4ya__d1s0ia1__1			Bacteroidetes		extracellular region [GO:0005576]; beta-agarase activity [GO:0033916]; carbohydrate metabolic process [GO:0005975]	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]		beta-agarase activity [GO:0033916]	exo-alpha-sialidase activity [GO:0004308]
d1o4za__d1bqp.1__1		Viridiplantae	Bacteroidetes	Streptophyta	cell outer membrane [GO:0009279]; beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]; carbohydrate metabolic process [GO:0005975]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]		cell outer membrane [GO:0009279]		beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1o4zb1_d2a3ws___1		Metazoa	Bacteroidetes	Chordata	cell outer membrane [GO:0009279]; beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]; carbohydrate metabolic process [GO:0005975]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate metabolic process [GO:0005975]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	cell outer membrane [GO:0009279]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1o4zd1_d3pvnd___1		Metazoa	Bacteroidetes	Chordata	cell outer membrane [GO:0009279]; beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	carbohydrate metabolic process [GO:0005975]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cell outer membrane [GO:0009279]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1o5a.1_d5hyob___1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]
d1o5b.1_d1s6ha___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	digestion [GO:0007586]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	extracellular space [GO:0005615]	serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1o5c.1_d2zu1b___1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host gene expression [GO:0039656]; modulation by virus of host NIK/NF-kappaB signaling [GO:0061765]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive regulation by virus of host cytokine production [GO:0044832]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host gene expression [GO:0039656]; modulation by virus of host NIK/NF-kappaB signaling [GO:0061765]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive regulation by virus of host cytokine production [GO:0044832]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1o5fl__d5hrja___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]; basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; scavenger receptor activity [GO:0005044]; virus receptor activity [GO:0001618]; acute-phase response [GO:0006953]	basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	acute-phase response [GO:0006953]	apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]	calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]	scavenger receptor activity [GO:0005044]; virus receptor activity [GO:0001618]
d1o5g.1_d4y79a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1o5ib__d4xwyd___1		Metazoa	Thermotogae	Chordata	NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [GO:0016628]; antibiotic biosynthetic process [GO:0017000]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; aldo-keto reductase (NADP) activity [GO:0004033]; NADP binding [GO:0050661]; sepiapterin reductase activity [GO:0004757]; cofactor metabolic process [GO:0051186]; nitric oxide biosynthetic process [GO:0006809]; oxidation-reduction process [GO:0055114]; regulation of nitric-oxide synthase activity [GO:0050999]; tetrahydrobiopterin biosynthetic process [GO:0006729]	antibiotic biosynthetic process [GO:0017000]	cofactor metabolic process [GO:0051186]; nitric oxide biosynthetic process [GO:0006809]; oxidation-reduction process [GO:0055114]; regulation of nitric-oxide synthase activity [GO:0050999]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [GO:0016628]	aldo-keto reductase (NADP) activity [GO:0004033]; NADP binding [GO:0050661]; sepiapterin reductase activity [GO:0004757]
d1o5nb__d4i3pa___1				Proteobacteria		3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]; 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]		'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]				3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]
d1o5nb__d4j1xa2__1				Actinobacteria		dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]				dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d1o5od1_d3mbia1__1			Thermotogae	Euryarchaeota	cytosol [GO:0005829]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]
d1o5ta__d3iuea___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; kinase inhibitor activity [GO:0019210]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tryptophan-tRNA ligase activity [GO:0004830]; angiogenesis [GO:0001525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; regulation of angiogenesis [GO:0045765]; regulation of protein ADP-ribosylation [GO:0010835]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]; beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	angiogenesis [GO:0001525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; regulation of angiogenesis [GO:0045765]; regulation of protein ADP-ribosylation [GO:0010835]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]	beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]	ATP binding [GO:0005524]; kinase inhibitor activity [GO:0019210]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]
d1o5xa__d2yc7a___1			Apicomplexa		identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]				identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	
d1o5za1_d2wjpa3__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; dihydrofolate synthase activity [GO:0008841]; tetrahydrofolylpolyglutamate synthase activity [GO:0004326]; folic acid-containing compound biosynthetic process [GO:0009396]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	folic acid-containing compound biosynthetic process [GO:0009396]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; dihydrofolate synthase activity [GO:0008841]; tetrahydrofolylpolyglutamate synthase activity [GO:0004326]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]
d1o61a__d1mgva___1			Proteobacteria	Proteobacteria	transaminase activity [GO:0008483]	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]		biotin biosynthetic process [GO:0009102]		cytoplasm [GO:0005737]	transaminase activity [GO:0008483]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]
d1o64b__d4r6ka___1			Thermotogae	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; histidine biosynthetic process [GO:0000105]		histidine biosynthetic process [GO:0000105]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]	
d1o6da1_d4faka1__1			Thermotogae	Firmicutes	cytoplasm [GO:0005737]; rRNA (pseudouridine-N3-)-methyltransferase activity [GO:0070038]	cytoplasm [GO:0005737]; rRNA (pseudouridine-N3-)-methyltransferase activity [GO:0070038]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	rRNA (pseudouridine-N3-)-methyltransferase activity [GO:0070038]	rRNA (pseudouridine-N3-)-methyltransferase activity [GO:0070038]
d1o6fa1_d2qr5a1__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type peptidase activity [GO:0008236]
d1o6fa2_d4bcca2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d1o6hc2_d3e33b___1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1o6jb__d1syxe___1		Metazoa		Chordata	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]	cell redox homeostasis [GO:0045454]	cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]	cell [GO:0005623]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		
d1o6pa__d3gnia___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; enzyme binding [GO:0019899]; Hsp90 protein binding [GO:0051879]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein domain specific binding [GO:0019904]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; apoptotic DNA fragmentation [GO:0006309]; astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; intracellular transport of virus [GO:0075733]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; modulation by virus of host cellular process [GO:0019054]; neutrophil degranulation [GO:0043312]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal protein import into nucleus [GO:0006610]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; serine/threonine protein kinase complex [GO:1902554]; kinase binding [GO:0019900]; protein kinase activator activity [GO:0030295]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674]; cell cycle arrest [GO:0007050]; cellular hypotonic response [GO:0071476]; intracellular signal transduction [GO:0035556]; negative regulation of potassium ion transmembrane transport [GO:1901380]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; neutrophil degranulation [GO:0043312]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein heterooligomerization [GO:0051291]; signal transduction by protein phosphorylation [GO:0023014]	apoptotic DNA fragmentation [GO:0006309]; astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; intracellular transport of virus [GO:0075733]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; modulation by virus of host cellular process [GO:0019054]; neutrophil degranulation [GO:0043312]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal protein import into nucleus [GO:0006610]	cell cycle arrest [GO:0007050]; cellular hypotonic response [GO:0071476]; intracellular signal transduction [GO:0035556]; negative regulation of potassium ion transmembrane transport [GO:1901380]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; neutrophil degranulation [GO:0043312]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein heterooligomerization [GO:0051291]; signal transduction by protein phosphorylation [GO:0023014]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; serine/threonine protein kinase complex [GO:1902554]	enzyme binding [GO:0019899]; Hsp90 protein binding [GO:0051879]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein domain specific binding [GO:0019904]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	kinase binding [GO:0019900]; protein kinase activator activity [GO:0030295]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674]
d1o6pb__d5n3wa3__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; enzyme binding [GO:0019899]; Hsp90 protein binding [GO:0051879]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein domain specific binding [GO:0019904]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; apoptotic DNA fragmentation [GO:0006309]; astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; intracellular transport of virus [GO:0075733]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; modulation by virus of host cellular process [GO:0019054]; neutrophil degranulation [GO:0043312]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal protein import into nucleus [GO:0006610]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	apoptotic DNA fragmentation [GO:0006309]; astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; intracellular transport of virus [GO:0075733]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; modulation by virus of host cellular process [GO:0019054]; neutrophil degranulation [GO:0043312]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal protein import into nucleus [GO:0006610]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	enzyme binding [GO:0019899]; Hsp90 protein binding [GO:0051879]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein domain specific binding [GO:0019904]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1o6qa2_d3oxua1__1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	hopanoid biosynthetic process [GO:0019746]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d1o6qc2_d1o1sb___1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1o6ra2_d3e30b___1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1o6sb1_d1ncia___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; fascia adherens [GO:0005916]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic specialization membrane [GO:0099060]; integral component of presynaptic active zone membrane [GO:0099059]; intercalated disc [GO:0014704]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; T-tubule [GO:0030315]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]; gamma-catenin binding [GO:0045295]; identical protein binding [GO:0042802]; nitric-oxide synthase binding [GO:0050998]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; adherens junction organization [GO:0034332]; blood vessel morphogenesis [GO:0048514]; brain morphogenesis [GO:0048854]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cerebral cortex development [GO:0021987]; glial cell differentiation [GO:0010001]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homeostasis of number of cells [GO:0048872]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neuroepithelial cell differentiation [GO:0060563]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; protein localization to plasma membrane [GO:0072659]; radial glial cell differentiation [GO:0060019]; regulation of axonogenesis [GO:0050770]; regulation of myelination [GO:0031641]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]; regulation of postsynaptic density protein 95 clustering [GO:1902897]; regulation of protein localization [GO:0032880]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synaptic transmission, glutamatergic [GO:0051966]; striated muscle cell differentiation [GO:0051146]; synapse assembly [GO:0007416]; telencephalon development [GO:0021537]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction organization [GO:0034332]; blood vessel morphogenesis [GO:0048514]; brain morphogenesis [GO:0048854]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cerebral cortex development [GO:0021987]; glial cell differentiation [GO:0010001]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homeostasis of number of cells [GO:0048872]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neuroepithelial cell differentiation [GO:0060563]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; protein localization to plasma membrane [GO:0072659]; radial glial cell differentiation [GO:0060019]; regulation of axonogenesis [GO:0050770]; regulation of myelination [GO:0031641]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]; regulation of postsynaptic density protein 95 clustering [GO:1902897]; regulation of protein localization [GO:0032880]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synaptic transmission, glutamatergic [GO:0051966]; striated muscle cell differentiation [GO:0051146]; synapse assembly [GO:0007416]; telencephalon development [GO:0021537]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell surface [GO:0009986]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; fascia adherens [GO:0005916]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic specialization membrane [GO:0099060]; integral component of presynaptic active zone membrane [GO:0099059]; intercalated disc [GO:0014704]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; T-tubule [GO:0030315]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]; gamma-catenin binding [GO:0045295]; identical protein binding [GO:0042802]; nitric-oxide synthase binding [GO:0050998]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]
d1o6ta2_d1m6ba2__1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; entry of bacterium into host cell [GO:0035635]; pathogenesis [GO:0009405]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; neuregulin binding [GO:0038132]; neuregulin receptor activity [GO:0038131]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activator activity [GO:0030296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; cranial nerve development [GO:0021545]; endocardial cushion development [GO:0003197]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; negative regulation of cell adhesion [GO:0007162]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of secretion [GO:0051048]; negative regulation of signal transduction [GO:0009968]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cardiac muscle tissue development [GO:0055025]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein tyrosine kinase activity [GO:0061098]; regulation of cell motility [GO:2000145]; regulation of cell population proliferation [GO:0042127]; Schwann cell differentiation [GO:0014037]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	entry of bacterium into host cell [GO:0035635]; pathogenesis [GO:0009405]	cranial nerve development [GO:0021545]; endocardial cushion development [GO:0003197]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; negative regulation of cell adhesion [GO:0007162]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of secretion [GO:0051048]; negative regulation of signal transduction [GO:0009968]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cardiac muscle tissue development [GO:0055025]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein tyrosine kinase activity [GO:0061098]; regulation of cell motility [GO:2000145]; regulation of cell population proliferation [GO:0042127]; Schwann cell differentiation [GO:0014037]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell wall [GO:0005618]; extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; neuregulin binding [GO:0038132]; neuregulin receptor activity [GO:0038131]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activator activity [GO:0030296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]
d1o6va1_d1h6ua1__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; entry of bacterium into host cell [GO:0035635]; pathogenesis [GO:0009405]	integral component of membrane [GO:0016021]	entry of bacterium into host cell [GO:0035635]; pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]	integral component of membrane [GO:0016021]		
d1o6xa__d1t1ea2__1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; extracellular space [GO:0005615]; vacuole [GO:0005773]; carboxypeptidase activity [GO:0004180]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; protein catabolic process in the vacuole [GO:0007039]; proteolysis [GO:0006508]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	protein catabolic process in the vacuole [GO:0007039]; proteolysis [GO:0006508]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; vacuole [GO:0005773]		carboxypeptidase activity [GO:0004180]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1o6za1_d1t2fc1__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; identical protein binding [GO:0042802]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; pyruvate metabolic process [GO:0006090]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; pyruvate metabolic process [GO:0006090]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]	L-malate dehydrogenase activity [GO:0030060]	identical protein binding [GO:0042802]; L-lactate dehydrogenase activity [GO:0004459]
d1o6zb2_d4ojng2__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-malate dehydrogenase activity [GO:0030060]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1o6zc2_d4bgvd2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]		L-malate dehydrogenase activity [GO:0030060]	L-malate dehydrogenase activity [GO:0030060]
d1o71b__d2ks4a___1	Metazoa	Metazoa	Cnidaria	Cnidaria	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]	cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]	cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]	channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	channel activity [GO:0015267]; toxin activity [GO:0090729]
d1o71b__d3qdvb___1	Metazoa	Fungi	Cnidaria	Basidiomycota	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]	carbohydrate binding [GO:0030246]	cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]		channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]
d1o75b1_d1o75a1__1			Spirochaetes	Spirochaetes	plasma membrane [GO:0005886]; peptidase activity [GO:0008233]; modulation by symbiont of microbe-associated molecular pattern-induced host innate immune response [GO:0052157]	plasma membrane [GO:0005886]; peptidase activity [GO:0008233]; modulation by symbiont of microbe-associated molecular pattern-induced host innate immune response [GO:0052157]	modulation by symbiont of microbe-associated molecular pattern-induced host innate immune response [GO:0052157]	modulation by symbiont of microbe-associated molecular pattern-induced host innate immune response [GO:0052157]	plasma membrane [GO:0005886]	plasma membrane [GO:0005886]	peptidase activity [GO:0008233]	peptidase activity [GO:0008233]
d1o79c2_d1dced___1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	Rab-protein geranylgeranyltransferase complex [GO:0005968]; isoprenoid binding [GO:0019840]; protein heterodimerization activity [GO:0046982]; Rab geranylgeranyltransferase activity [GO:0004663]; Rab GTPase binding [GO:0017137]; zinc ion binding [GO:0008270]; protein geranylgeranylation [GO:0018344]; protein prenylation [GO:0018342]; protein-containing complex assembly [GO:0065003]	hopanoid biosynthetic process [GO:0019746]	protein-containing complex assembly [GO:0065003]; protein geranylgeranylation [GO:0018344]; protein prenylation [GO:0018342]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	Rab-protein geranylgeranyltransferase complex [GO:0005968]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	isoprenoid binding [GO:0019840]; protein heterodimerization activity [GO:0046982]; Rab geranylgeranyltransferase activity [GO:0004663]; Rab GTPase binding [GO:0017137]; zinc ion binding [GO:0008270]
d1o7fa1_d5fd6b___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cilium [GO:0005929]; cone cell pedicle [GO:0044316]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; neuronal cell body [GO:0043025]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; cAMP binding [GO:0030552]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein-containing complex binding [GO:0044877]; Ras GTPase binding [GO:0017016]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; calcium-ion regulated exocytosis [GO:0017156]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of protein secretion [GO:0050714]; positive regulation of smooth muscle cell migration [GO:0014911]; regulation of dendrite development [GO:0050773]; regulation of exocytosis [GO:0017157]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of postsynapse organization [GO:0099175]; regulation of synaptic vesicle cycle [GO:0098693]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]	calcium-ion regulated exocytosis [GO:0017156]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of protein secretion [GO:0050714]; positive regulation of smooth muscle cell migration [GO:0014911]; regulation of dendrite development [GO:0050773]; regulation of exocytosis [GO:0017157]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of postsynapse organization [GO:0099175]; regulation of synaptic vesicle cycle [GO:0098693]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]		apical plasma membrane [GO:0016324]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cilium [GO:0005929]; cone cell pedicle [GO:0044316]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; neuronal cell body [GO:0043025]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	cAMP binding [GO:0030552]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein-containing complex binding [GO:0044877]; Ras GTPase binding [GO:0017016]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]
d1o7fa2_d5c8wd___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cilium [GO:0005929]; cone cell pedicle [GO:0044316]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; neuronal cell body [GO:0043025]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; cAMP binding [GO:0030552]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein-containing complex binding [GO:0044877]; Ras GTPase binding [GO:0017016]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; calcium-ion regulated exocytosis [GO:0017156]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of protein secretion [GO:0050714]; positive regulation of smooth muscle cell migration [GO:0014911]; regulation of dendrite development [GO:0050773]; regulation of exocytosis [GO:0017157]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of postsynapse organization [GO:0099175]; regulation of synaptic vesicle cycle [GO:0098693]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; cofactor metabolic process [GO:0051186]; negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	calcium-ion regulated exocytosis [GO:0017156]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of protein secretion [GO:0050714]; positive regulation of smooth muscle cell migration [GO:0014911]; regulation of dendrite development [GO:0050773]; regulation of exocytosis [GO:0017157]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of postsynapse organization [GO:0099175]; regulation of synaptic vesicle cycle [GO:0098693]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]	cofactor metabolic process [GO:0051186]; negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cilium [GO:0005929]; cone cell pedicle [GO:0044316]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; neuronal cell body [GO:0043025]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]	cAMP binding [GO:0030552]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein-containing complex binding [GO:0044877]; Ras GTPase binding [GO:0017016]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]	ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]
d1o7fa3_d3r6sa1__1	Metazoa		Chordata	Actinobacteria	apical plasma membrane [GO:0016324]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cilium [GO:0005929]; cone cell pedicle [GO:0044316]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; neuronal cell body [GO:0043025]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; cAMP binding [GO:0030552]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein-containing complex binding [GO:0044877]; Ras GTPase binding [GO:0017016]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; calcium-ion regulated exocytosis [GO:0017156]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of protein secretion [GO:0050714]; positive regulation of smooth muscle cell migration [GO:0014911]; regulation of dendrite development [GO:0050773]; regulation of exocytosis [GO:0017157]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of postsynapse organization [GO:0099175]; regulation of synaptic vesicle cycle [GO:0098693]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]	protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	calcium-ion regulated exocytosis [GO:0017156]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of protein secretion [GO:0050714]; positive regulation of smooth muscle cell migration [GO:0014911]; regulation of dendrite development [GO:0050773]; regulation of exocytosis [GO:0017157]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of postsynapse organization [GO:0099175]; regulation of synaptic vesicle cycle [GO:0098693]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]	regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	apical plasma membrane [GO:0016324]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cilium [GO:0005929]; cone cell pedicle [GO:0044316]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; neuronal cell body [GO:0043025]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]	protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein-containing complex binding [GO:0044877]; Ras GTPase binding [GO:0017016]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1o7ga2_d2bmqa2__1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]			dioxygenase activity [GO:0051213]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1o7ha2_d3gzya2__1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			dioxygenase activity [GO:0051213]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1o7ib__d4ipca1__1		Metazoa	Crenarchaeota	Chordata	DNA binding [GO:0003677]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle checkpoint [GO:0007093]; response to ionizing radiation [GO:0010212]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]; damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle checkpoint [GO:0007093]; response to ionizing radiation [GO:0010212]	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]		DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]	DNA binding [GO:0003677]	damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]
d1o7lb2_d1fr3k___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]; molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]	
d1o7lb3_d1gunf___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]; molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]	
d1o7ld3_d1gugc___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]; molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	molybdate ion transport [GO:0015689]	cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; molybdenum ion binding [GO:0030151]	
d1o7ma1_d3l73r2__1		Metazoa	Proteobacteria	Chordata	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	aromatic compound catabolic process [GO:0019439]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	dioxygenase activity [GO:0051213]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1o7mb__d2bmrb___1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]			dioxygenase activity [GO:0051213]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1o7mb__d3wmdb1__1			Proteobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	isomerase activity [GO:0016853]	aromatic compound catabolic process [GO:0019439]				dioxygenase activity [GO:0051213]	isomerase activity [GO:0016853]
d1o7na1_d1nyka___1			Proteobacteria	Deinococcus-Thermus	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]	aromatic compound catabolic process [GO:0019439]			integral component of membrane [GO:0016021]	dioxygenase activity [GO:0051213]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]
d1o7na2_d4n3el___1		Viridiplantae	Proteobacteria	Streptophyta	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]			dioxygenase activity [GO:0051213]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d1o7nb__d1uljd___1			Proteobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			dioxygenase activity [GO:0051213]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1o7pb__d3mg1a2__1			Proteobacteria	Cyanobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	phycobilisome [GO:0030089]; chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]; light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	aromatic compound catabolic process [GO:0019439]	light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	dioxygenase activity [GO:0051213]	chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]
d1o7tb__d4glia___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	transmembrane transport [GO:0055085]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1o7tc__d2xd2b___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; transmembrane transport [GO:0055085]	plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]	transmembrane transport [GO:0055085]			plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	carbohydrate transmembrane transporter activity [GO:0015144]
d1o7te__d5l8da___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	transmembrane transport [GO:0055085]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]
d1o7th__d4z7ea___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; SOS response [GO:0009432]	transmembrane transport [GO:0055085]	SOS response [GO:0009432]		ATP-binding cassette (ABC) transporter complex [GO:0043190]	metal ion binding [GO:0046872]	transmembrane transporter activity [GO:0022857]
d1o7wb__d4r9la1__1			Proteobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	limonene-1,2-epoxide hydrolase activity [GO:0018744]	aromatic compound catabolic process [GO:0019439]				dioxygenase activity [GO:0051213]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d1o7wb__d5aeub___1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			dioxygenase activity [GO:0051213]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1o7xa__d3o8jf___1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; citrate (Si)-synthase activity [GO:0004108]; carbohydrate metabolic process [GO:0005975]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; 2-methylcitrate synthase activity [GO:0050440]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]; carbohydrate metabolic process [GO:0005975]; propionate metabolic process, methylcitrate cycle [GO:0019679]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; propionate metabolic process, methylcitrate cycle [GO:0019679]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]	citrate (Si)-synthase activity [GO:0004108]	2-methylcitrate synthase activity [GO:0050440]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]
d1o7ya__d1f9sd___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cAMP-dependent protein kinase regulator activity [GO:0008603]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]; signaling receptor binding [GO:0005102]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood circulation [GO:0008015]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular response to heat [GO:0034605]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; endothelial cell activation [GO:0042118]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; muscle organ development [GO:0007517]; negative regulation of angiogenesis [GO:0016525]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast fusion [GO:1901740]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of endothelial tube morphogenesis [GO:1901509]; regulation of T cell chemotaxis [GO:0010819]; response to auditory stimulus [GO:0010996]; response to cold [GO:0009409]; response to gamma radiation [GO:0010332]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell chemotaxis [GO:0010818]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]; chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood circulation [GO:0008015]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular response to heat [GO:0034605]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; endothelial cell activation [GO:0042118]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; muscle organ development [GO:0007517]; negative regulation of angiogenesis [GO:0016525]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast fusion [GO:1901740]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of endothelial tube morphogenesis [GO:1901509]; regulation of T cell chemotaxis [GO:0010819]; response to auditory stimulus [GO:0010996]; response to cold [GO:0009409]; response to gamma radiation [GO:0010332]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell chemotaxis [GO:0010818]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	cell [GO:0005623]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]	cAMP-dependent protein kinase regulator activity [GO:0008603]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]; signaling receptor binding [GO:0005102]	chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]
d1o81a__d3tjkb___1		Metazoa		Chordata	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]		protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d1o81b__d2myga1__1					cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]		electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d1o89a2_d1hetb2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; acryloyl-CoA reductase (NADP+) activity [GO:0043957]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acryloyl-CoA reductase (NADP+) activity [GO:0043957]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1o8ca4_d1mp0b2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; acryloyl-CoA reductase (NADP+) activity [GO:0043957]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]		ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	acryloyl-CoA reductase (NADP+) activity [GO:0043957]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]
d1o8cd4_d1mc5a2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; acryloyl-CoA reductase (NADP+) activity [GO:0043957]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]		ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	acryloyl-CoA reductase (NADP+) activity [GO:0043957]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]
d1o8ha__d1k5ca___1		Fungi	Proteobacteria	Basidiomycota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	polygalacturonase activity [GO:0004650]
d1o8ia__d1ofma___1			Proteobacteria	Bacteroidetes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	chondroitin B lyase activity [GO:0033999]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]		extracellular region [GO:0005576]		metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	chondroitin B lyase activity [GO:0033999]
d1o8ka__d2vfoa___1			Proteobacteria		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	virus tail, fiber [GO:0098024]; endo-1,3-alpha-L-rhamnosidase activity [GO:0052775]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption by virus of host envelope lipopolysaccharide during virus entry [GO:0098995]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]; virion attachment to host cell [GO:0019062]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption by virus of host envelope lipopolysaccharide during virus entry [GO:0098995]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	virus tail, fiber [GO:0098024]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	endo-1,3-alpha-L-rhamnosidase activity [GO:0052775]
d1o8nb__d1o8qf___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; auxin-activated signaling pathway [GO:0009734]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; auxin-activated signaling pathway [GO:0009734]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; response to metal ion [GO:0010038]	auxin-activated signaling pathway [GO:0009734]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; response to metal ion [GO:0010038]	auxin-activated signaling pathway [GO:0009734]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]	ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]
d1o8nb__d3mcha___1	Viridiplantae		Streptophyta	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; auxin-activated signaling pathway [GO:0009734]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; response to metal ion [GO:0010038]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	auxin-activated signaling pathway [GO:0009734]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; response to metal ion [GO:0010038]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]	
d1o8oa__d2pjka___1	Viridiplantae		Streptophyta		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; auxin-activated signaling pathway [GO:0009734]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; response to metal ion [GO:0010038]		auxin-activated signaling pathway [GO:0009734]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; response to metal ion [GO:0010038]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]	
d1o8ob__d1o8qh___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; auxin-activated signaling pathway [GO:0009734]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; auxin-activated signaling pathway [GO:0009734]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; response to metal ion [GO:0010038]	auxin-activated signaling pathway [GO:0009734]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; response to metal ion [GO:0010038]	auxin-activated signaling pathway [GO:0009734]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]	ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]
d1o8qe__d3tcrb___1	Viridiplantae		Streptophyta	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; auxin-activated signaling pathway [GO:0009734]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; response to metal ion [GO:0010038]		auxin-activated signaling pathway [GO:0009734]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; response to metal ion [GO:0010038]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]	
d1o8qh__d3iwtc___1	Viridiplantae		Streptophyta	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; auxin-activated signaling pathway [GO:0009734]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; response to metal ion [GO:0010038]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	auxin-activated signaling pathway [GO:0009734]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; response to metal ion [GO:0010038]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]	
d1o8sa__d1px3b3__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1o8ue__d1xnwb2__1			Actinobacteria	Actinobacteria	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		acetyl-CoA carboxylase complex [GO:0009317]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]
d1o8wa__d3u5re___1				Proteobacteria	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]		antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]
d1o8xa__d3a2xh___1				Crenarchaeota	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]		antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1o90b1_d1o93b2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]
d1o90b2_d4odja1__1	Metazoa		Chordata		cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]		methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]		cytosol [GO:0005829]; nuclear matrix [GO:0016363]		ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	
d1o92a2_d3rv2a2__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]
d1o92a3_d3so4a3__1	Metazoa		Chordata		cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	cytosol [GO:0005829]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d1o92b2_d2obva2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; methionine catabolic process [GO:0009087]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; S-adenosylmethionine biosynthetic process [GO:0006556]; selenium compound metabolic process [GO:0001887]; sulfur amino acid metabolic process [GO:0000096]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; S-adenosylmethionine biosynthetic process [GO:0006556]; selenium compound metabolic process [GO:0001887]; sulfur amino acid metabolic process [GO:0000096]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	cytosol [GO:0005829]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d1o92b3_d5h9uc3__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]
d1o93a3_d3so4b2__1	Metazoa		Chordata		cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	cytosol [GO:0005829]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d1o93b1_d3s82a3__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]
d1o94a2_d1lpfb2__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	cell [GO:0005623]; cytoplasm [GO:0005737]; dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]; glycolytic process [GO:0006096]		cell redox homeostasis [GO:0045454]; glycolytic process [GO:0006096]		cell [GO:0005623]; cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]
d1o95f__d4l2ib___1			Proteobacteria	Firmicutes	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]					4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]
d1o96b2_d1t9ba1__1		Fungi	Proteobacteria	Ascomycota	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1o96z2_d2wvhf2__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]					electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1o9id__d3rngb___1			Firmicutes	Proteobacteria	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]		cellular aromatic compound metabolic process [GO:0006725]			catalase activity [GO:0004096]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d1o9ja__d1of7b___1	Metazoa		Chordata		cytoplasm [GO:0005737]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; ethanol catabolic process [GO:0006068]; protein homotetramerization [GO:0051289]; retinal metabolic process [GO:0042574]		ethanol catabolic process [GO:0006068]; protein homotetramerization [GO:0051289]; retinal metabolic process [GO:0042574]		cytoplasm [GO:0005737]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]	
d1o9ja__d4ni4h___1	Metazoa		Chordata		cytoplasm [GO:0005737]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; ethanol catabolic process [GO:0006068]; protein homotetramerization [GO:0051289]; retinal metabolic process [GO:0042574]		ethanol catabolic process [GO:0006068]; protein homotetramerization [GO:0051289]; retinal metabolic process [GO:0042574]		cytoplasm [GO:0005737]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]	
d1o9jb__d1ez0b___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; ethanol catabolic process [GO:0006068]; protein homotetramerization [GO:0051289]; retinal metabolic process [GO:0042574]	aldehyde dehydrogenase (NADP+) activity [GO:0033721]	ethanol catabolic process [GO:0006068]; protein homotetramerization [GO:0051289]; retinal metabolic process [GO:0042574]		cytoplasm [GO:0005737]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]	aldehyde dehydrogenase (NADP+) activity [GO:0033721]
d1o9kh__d1e9hd2__1	Metazoa	Metazoa	Chordata	Chordata	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]; androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1o9la2_d5n01d___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	CoA-transferase activity [GO:0008410]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]		mitochondrion [GO:0005739]		3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	CoA-transferase activity [GO:0008410]
d1o9lb1_d2ahwd2__1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	acetate CoA-transferase activity [GO:0008775]; ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]	mitochondrion [GO:0005739]		3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	acetate CoA-transferase activity [GO:0008775]
d1o9lc1_d5mzwb___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	CoA-transferase activity [GO:0008410]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]		mitochondrion [GO:0005739]		3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	CoA-transferase activity [GO:0008410]
d1o9ld1_d1poic___1	Metazoa		Chordata	Firmicutes	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	cytoplasm [GO:0005737]; glutaconate CoA-transferase activity [GO:0018730]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]	mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	glutaconate CoA-transferase activity [GO:0018730]
d1o9na__d1mt5f___1		Metazoa	Proteobacteria	Chordata	amidase activity [GO:0004040]	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]	amidase activity [GO:0004040]	acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]
d1o9oa__d3ppma___1		Metazoa	Proteobacteria	Chordata	amidase activity [GO:0004040]	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]	amidase activity [GO:0004040]	acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]
d1o9ob__d1mt5k___1		Metazoa	Proteobacteria	Chordata	amidase activity [GO:0004040]	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]	amidase activity [GO:0004040]	acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]
d1o9rb__d4cmyf___1			Proteobacteria	Chlorobi	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d1o9re__d5jkmg___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1o9sa2_d5tuya___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; C2H2 zinc finger domain binding [GO:0070742]; histone methyltransferase activity (H3-K27 specific) [GO:0046976]; histone methyltransferase activity (H3-K9 specific) [GO:0046974]; histone-lysine N-methyltransferase activity [GO:0018024]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protein-lysine N-methyltransferase activity [GO:0016279]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; DNA methylation [GO:0006306]; histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; regulation of DNA replication [GO:0006275]; regulation of signal transduction by p53 class mediator [GO:1901796]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	cellular response to starvation [GO:0009267]; DNA methylation [GO:0006306]; histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; regulation of DNA replication [GO:0006275]; regulation of signal transduction by p53 class mediator [GO:1901796]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	C2H2 zinc finger domain binding [GO:0070742]; histone-lysine N-methyltransferase activity [GO:0018024]; histone methyltransferase activity (H3-K27 specific) [GO:0046976]; histone methyltransferase activity (H3-K9 specific) [GO:0046974]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protein-lysine N-methyltransferase activity [GO:0016279]; zinc ion binding [GO:0008270]
d1o9sb2_d2g46a___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	identical protein binding [GO:0042802]; methyltransferase activity [GO:0008168]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	identical protein binding [GO:0042802]; methyltransferase activity [GO:0008168]
d1o9ta2_d1fugb2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	cytosol [GO:0005829]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d1o9ta2_d5t8ta3__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]
d1o9xa3_d2bxca1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1oa2e__d1h4hb___1	Fungi		Ascomycota	Firmicutes	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]			cellulase activity [GO:0008810]	endo-1,4-beta-xylanase activity [GO:0031176]
d1oa3a__d3ojbc1__1	Fungi	Metazoa	Ascomycota	Chordata	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	polysaccharide catabolic process [GO:0000272]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	cellulase activity [GO:0008810]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d1oa3d__d1wlwa___1	Fungi	Metazoa	Ascomycota	Chordata	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]	polysaccharide catabolic process [GO:0000272]				cellulase activity [GO:0008810]	carbohydrate binding [GO:0030246]
d1oa8b__d4aqpa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; poly(G) binding [GO:0034046]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; protein self-association [GO:0043621]; anatomical structure development [GO:0048856]; brain development [GO:0007420]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; nuclear export [GO:0051168]; regulation of transcription, DNA-templated [GO:0006355]; RNA processing [GO:0006396]; social behavior [GO:0035176]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; poly(G) binding [GO:0034046]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; protein self-association [GO:0043621]; anatomical structure development [GO:0048856]; brain development [GO:0007420]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; nuclear export [GO:0051168]; regulation of transcription, DNA-templated [GO:0006355]; RNA processing [GO:0006396]; social behavior [GO:0035176]	anatomical structure development [GO:0048856]; brain development [GO:0007420]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; nuclear export [GO:0051168]; regulation of transcription, DNA-templated [GO:0006355]; RNA processing [GO:0006396]; social behavior [GO:0035176]	anatomical structure development [GO:0048856]; brain development [GO:0007420]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; nuclear export [GO:0051168]; regulation of transcription, DNA-templated [GO:0006355]; RNA processing [GO:0006396]; social behavior [GO:0035176]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; poly(G) binding [GO:0034046]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; protein self-association [GO:0043621]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; poly(G) binding [GO:0034046]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; protein self-association [GO:0043621]
d1oacb2_d1ui8b2__1			Proteobacteria	Actinobacteria	periplasmic space [GO:0042597]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	amine metabolic process [GO:0009308]	periplasmic space [GO:0042597]		aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d1oadb__d1de6b___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; L-rhamnose isomerase activity [GO:0008740]; manganese ion binding [GO:0030145]; rhamnose binding [GO:0033296]; zinc ion binding [GO:0008270]; L-lyxose metabolic process [GO:0019324]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]	D-xylose metabolic process [GO:0042732]	L-lyxose metabolic process [GO:0019324]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	identical protein binding [GO:0042802]; L-rhamnose isomerase activity [GO:0008740]; manganese ion binding [GO:0030145]; rhamnose binding [GO:0033296]; zinc ion binding [GO:0008270]
d1oafa1_d5txqa2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]		heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1oaga__d5fnba___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]	extracellular region [GO:0005576]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]
d1oaja__d3gqff___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	periplasmic space [GO:0042597]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1oakh1_d2ianq1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1oakl2_d1jl4d2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1oama2_d1l9nb1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]		cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]		calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]
d1oanb1_d1smab1__1				Deinococcus-Thermus	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]
d1oanb1_d3irca___1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1oaqh__d1otuc1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1oarl__d3tlrc1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1oasb__d5i7rb___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; O-phosphoserine sulfhydrylase activity [GO:0033847]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; O-phosphoserine sulfhydrylase activity [GO:0033847]; pyridoxal phosphate binding [GO:0030170]
d1oatc__d1qz9a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; kynureninase activity [GO:0030429]; pyridoxal phosphate binding [GO:0030170]; 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; L-kynurenine catabolic process [GO:0097053]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]	arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; L-kynurenine catabolic process [GO:0097053]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]	kynureninase activity [GO:0030429]; pyridoxal phosphate binding [GO:0030170]
d1oauh__d2edta1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]		ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]
d1oaxl__d4k3hb___1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1oaxn__d4gw1c1__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1oaxn__d5h35i1__1	Metazoa		Chordata	Crenarchaeota	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		
d1oayl__d1u8ma1__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1oayl__d3nh7m1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; dorsal aorta morphogenesis [GO:0035912]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]
d1oazj__d1rupl2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1oazl__d1vfba___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1oazl__d3eoaa2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]
d1ob1a1_d1xf4l1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ob1b1_d1rz8a1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ob1b2_d2a6jl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ob1d2_d1fvea1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ob5a3_d4ioja___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; tetrahydrofolate interconversion [GO:0035999]		tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]
d1ob5c2_d1d2ed2__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]		mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1ob5c2_d3cw2f3__1			Deinococcus-Thermus	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1ob9a__d3bama___1			Crenarchaeota	Firmicutes	crossover junction endodeoxyribonuclease activity [GO:0008821]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]	DNA restriction-modification system [GO:0009307]			crossover junction endodeoxyribonuclease activity [GO:0008821]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]
d1obaa2_d1sfsa___1				Firmicutes	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]				lysozyme activity [GO:0003796]	
d1obba1_d5uawe1__1		Metazoa	Thermotogae	Chordata	maltose alpha-glucosidase activity [GO:0032450]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]		cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	maltose alpha-glucosidase activity [GO:0032450]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1obga__d4o7ya___1	Fungi		Ascomycota	Euryarchaeota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [GO:0004639]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	ATP binding [GO:0005524]; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [GO:0004639]; 'de novo' IMP biosynthetic process [GO:0006189]; cobalamin biosynthetic process [GO:0009236]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' IMP biosynthetic process [GO:0006189]; cobalamin biosynthetic process [GO:0009236]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		ATP binding [GO:0005524]; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [GO:0004639]	ATP binding [GO:0005524]; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [GO:0004639]
d1obka__d1mt5o___1		Metazoa	Proteobacteria	Chordata	amidase activity [GO:0004040]	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]	amidase activity [GO:0004040]	acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]
d1oboa__d2faxa___1			Cyanobacteria	Firmicutes	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]		cell [GO:0005623]		electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1obob__d1i1oa___1			Cyanobacteria	Proteobacteria	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]		cell [GO:0005623]		electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1obob__d3gfrc___1			Cyanobacteria	Firmicutes	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]		cell [GO:0005623]	cytosol [GO:0005829]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d1obpa__d1crba___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cell body [GO:0044297]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; lipid homeostasis [GO:0055088]; regulation of granulocyte differentiation [GO:0030852]; response to vitamin A [GO:0033189]; retinoic acid biosynthetic process [GO:0002138]; retinol metabolic process [GO:0042572]; vitamin A metabolic process [GO:0006776]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	lipid homeostasis [GO:0055088]; regulation of granulocyte differentiation [GO:0030852]; response to vitamin A [GO:0033189]; retinoic acid biosynthetic process [GO:0002138]; retinol metabolic process [GO:0042572]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cell body [GO:0044297]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]	small molecule binding [GO:0036094]	all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinol binding [GO:0019841]
d1obqb__d2l9ca1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular space [GO:0005615]; pigment binding [GO:0031409]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; mating pheromone activity [GO:0000772]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; olfactory learning [GO:0008355]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]		aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; olfactory learning [GO:0008355]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	pigment binding [GO:0031409]	insulin-activated receptor activity [GO:0005009]; mating pheromone activity [GO:0000772]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]
d1obra__d4ik2a___1			Firmicutes	Firmicutes	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]					metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1obsa__d4z9wa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1obua__d3vg7a1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular space [GO:0005615]; pigment binding [GO:0031409]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]		cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	extracellular space [GO:0005615]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	pigment binding [GO:0031409]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]
d1obva__d5fa6b1__1		Metazoa	Cyanobacteria	Chordata	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1obwb__d2bqya___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1obxa__d1fcfa3__1	Metazoa	Viridiplantae	Chordata	Chlorophyta	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]	chloroplast thylakoid lumen [GO:0009543]; serine-type peptidase activity [GO:0008236]	cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	chloroplast thylakoid lumen [GO:0009543]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]	serine-type peptidase activity [GO:0008236]
d1obya1_d3lnxe___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; costamere [GO:0043034]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; lysosomal lumen [GO:0043202]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; protein kinase C binding [GO:0005080]; thrombospondin receptor activity [GO:0070053]; cell migration [GO:0016477]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell stereocilium organization [GO:0060122]; leukocyte migration [GO:0050900]; negative regulation of T cell proliferation [GO:0042130]; neural tube closure [GO:0001843]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of stress fiber assembly [GO:0051496]; regulation of fibroblast migration [GO:0010762]; retinoid metabolic process [GO:0001523]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	cell migration [GO:0016477]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell stereocilium organization [GO:0060122]; leukocyte migration [GO:0050900]; negative regulation of T cell proliferation [GO:0042130]; neural tube closure [GO:0001843]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of stress fiber assembly [GO:0051496]; regulation of fibroblast migration [GO:0010762]; retinoid metabolic process [GO:0001523]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]	cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	cell surface [GO:0009986]; costamere [GO:0043034]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; lysosomal lumen [GO:0043202]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; protein kinase C binding [GO:0005080]; thrombospondin receptor activity [GO:0070053]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]
d1obyb__d1wg6a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; costamere [GO:0043034]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; lysosomal lumen [GO:0043202]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; protein kinase C binding [GO:0005080]; thrombospondin receptor activity [GO:0070053]; cell migration [GO:0016477]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell stereocilium organization [GO:0060122]; leukocyte migration [GO:0050900]; negative regulation of T cell proliferation [GO:0042130]; neural tube closure [GO:0001843]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of stress fiber assembly [GO:0051496]; regulation of fibroblast migration [GO:0010762]; retinoid metabolic process [GO:0001523]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; nuclear body [GO:0016604]; protein-containing complex [GO:0032991]; phosphatidylinositol binding [GO:0035091]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; protein localization [GO:0008104]	cell migration [GO:0016477]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell stereocilium organization [GO:0060122]; leukocyte migration [GO:0050900]; negative regulation of T cell proliferation [GO:0042130]; neural tube closure [GO:0001843]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of stress fiber assembly [GO:0051496]; regulation of fibroblast migration [GO:0010762]; retinoid metabolic process [GO:0001523]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]	cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; protein localization [GO:0008104]	cell surface [GO:0009986]; costamere [GO:0043034]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; lysosomal lumen [GO:0043202]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; nuclear body [GO:0016604]; protein-containing complex [GO:0032991]	fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; protein kinase C binding [GO:0005080]; thrombospondin receptor activity [GO:0070053]	phosphatidylinositol binding [GO:0035091]
d1obzb1_d2m0za1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]	cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]
d1obzb2_d2q3gb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]	actin cytoskeleton [GO:0015629]; cell-cell adherens junction [GO:0005913]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; ruffle [GO:0001726]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; actin cytoskeleton organization [GO:0030036]; axon guidance [GO:0007411]; heart development [GO:0007507]; muscle structure development [GO:0061061]; ossification [GO:0001503]; positive regulation of osteoblast differentiation [GO:0045669]; receptor-mediated endocytosis [GO:0006898]	cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]	actin cytoskeleton organization [GO:0030036]; axon guidance [GO:0007411]; heart development [GO:0007507]; muscle structure development [GO:0061061]; ossification [GO:0001503]; positive regulation of osteoblast differentiation [GO:0045669]; receptor-mediated endocytosis [GO:0006898]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	actin cytoskeleton [GO:0015629]; cell-cell adherens junction [GO:0005913]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; ruffle [GO:0001726]; stress fiber [GO:0001725]; Z disc [GO:0030018]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]	actin binding [GO:0003779]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]
d1oc2a__d1uaya___1			Firmicutes	Deinococcus-Thermus	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]; nucleotide-sugar metabolic process [GO:0009225]	oxidoreductase activity [GO:0016491]	nucleotide-sugar metabolic process [GO:0009225]				dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]	oxidoreductase activity [GO:0016491]
d1oc2b__d5trta___1			Firmicutes	Proteobacteria	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]; nucleotide-sugar metabolic process [GO:0009225]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	nucleotide-sugar metabolic process [GO:0009225]	fatty acid biosynthetic process [GO:0006633]			dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d1oc3a1_d3h79a___1	Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cell [GO:0005623]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]	
d1oc3c__d4x43a___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1oc6a__d3voga1__1	Fungi	Fungi	Ascomycota	Basidiomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1oc9a__d3dexc___1				Actinobacteria	cell [GO:0005623]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]			
d1oc9b__d1beda___1				Proteobacteria	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; pathogenesis [GO:0009405]; protein folding [GO:0006457]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; pathogenesis [GO:0009405]; protein folding [GO:0006457]	cell [GO:0005623]	cell [GO:0005623]; periplasmic space [GO:0042597]		protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d1ocaa__d4j5ex___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]
d1ocja__d5xcya___1	Fungi	Fungi	Ascomycota	Basidiomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1ocka__d1mt5c___1		Metazoa	Proteobacteria	Chordata	amidase activity [GO:0004040]	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]	amidase activity [GO:0004040]	acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]
d1ocna__d2bvwb___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d1ocrb1_d4knue1__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	ATP synthesis coupled electron transport [GO:0042773]	nitrogen compound metabolic process [GO:0006807]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]		copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1ocro1_d2ve0a3__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]		ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]		copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	
d1ocvc__d1jb2a___1		Metazoa	Proteobacteria	Chordata	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	steroid metabolic process [GO:0008202]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]		cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	steroid delta-isomerase activity [GO:0004769]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]
d1ocwl__d3fo9h2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ocxc__d4myob1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; identical protein binding [GO:0042802]; maltose O-acetyltransferase activity [GO:0008925]; protein homotrimerization [GO:0070207]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	protein homotrimerization [GO:0070207]	response to antibiotic [GO:0046677]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; maltose O-acetyltransferase activity [GO:0008925]	transferase activity, transferring acyl groups [GO:0016746]
d1ocya__d1h6w.2__1					virion [GO:0019012]; virus tail, baseplate [GO:0098025]; virus tail, fiber [GO:0098024]; metal ion binding [GO:0046872]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	virion [GO:0019012]; virus tail, baseplate [GO:0098025]; virus tail, fiber [GO:0098024]; metal ion binding [GO:0046872]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	virion [GO:0019012]; virus tail, baseplate [GO:0098025]; virus tail, fiber [GO:0098024]	virion [GO:0019012]; virus tail, baseplate [GO:0098025]; virus tail, fiber [GO:0098024]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1oczo1_d3ugeb___1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	ATP synthesis coupled electron transport [GO:0042773]	oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1od3a__d1jz8a3__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1od5a2_d4yyoa___1	Viridiplantae	Metazoa	Streptophyta	Chordata	aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]		cysteine metabolic process [GO:0006534]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]	cytosol [GO:0005829]	nutrient reservoir activity [GO:0045735]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d1od7a__d1hxmb1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	carbohydrate binding [GO:0030246]	transmembrane signaling receptor activity [GO:0004888]
d1od8a__d1bgld5__1			Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	
d1odbc1_d2vaya___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1odia__d1y1sc___1			Deinococcus-Thermus	Proteobacteria	transferase activity, transferring pentosyl groups [GO:0016763]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]		cytoplasm [GO:0005737]	transferase activity, transferring pentosyl groups [GO:0016763]	uridine phosphorylase activity [GO:0004850]
d1odic__d5lu0e___1			Deinococcus-Thermus	Proteobacteria	transferase activity, transferring pentosyl groups [GO:0016763]; nucleoside metabolic process [GO:0009116]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	nucleoside metabolic process [GO:0009116]	purine nucleoside metabolic process [GO:0042278]			transferase activity, transferring pentosyl groups [GO:0016763]	purine-nucleoside phosphorylase activity [GO:0004731]
d1odif__d3t94a___1			Deinococcus-Thermus	Crenarchaeota	transferase activity, transferring pentosyl groups [GO:0016763]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	nucleoside metabolic process [GO:0009116]	L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	transferase activity, transferring pentosyl groups [GO:0016763]	S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]
d1odja__d3e9za___1		Metazoa	Deinococcus-Thermus	Platyhelminthes	transferase activity, transferring pentosyl groups [GO:0016763]; nucleoside metabolic process [GO:0009116]	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]			transferase activity, transferring pentosyl groups [GO:0016763]	purine-nucleoside phosphorylase activity [GO:0004731]
d1odje__d5k1za___1			Deinococcus-Thermus	Proteobacteria	transferase activity, transferring pentosyl groups [GO:0016763]; nucleoside metabolic process [GO:0009116]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	nucleoside metabolic process [GO:0009116]	L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]			transferase activity, transferring pentosyl groups [GO:0016763]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d1odkf__d1nc3b___1			Deinococcus-Thermus	Proteobacteria	transferase activity, transferring pentosyl groups [GO:0016763]; nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]; adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]	nucleoside metabolic process [GO:0009116]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]		cytosol [GO:0005829]	transferase activity, transferring pentosyl groups [GO:0016763]	adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]
d1odla__d1zosb___1			Deinococcus-Thermus	Firmicutes	transferase activity, transferring pentosyl groups [GO:0016763]; nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]	nucleoside metabolic process [GO:0009116]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]		cytosol [GO:0005829]	transferase activity, transferring pentosyl groups [GO:0016763]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d1odlb__d1k9se___1			Deinococcus-Thermus	Proteobacteria	transferase activity, transferring pentosyl groups [GO:0016763]; nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	nucleoside metabolic process [GO:0009116]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]		cytosol [GO:0005829]; membrane [GO:0016020]	transferase activity, transferring pentosyl groups [GO:0016763]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]
d1odsa__d4oyyb___1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]		cytoplasm [GO:0005737]	extracellular region [GO:0005576]	acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]	cutinase activity [GO:0050525]
d1odsb__d1uk6a___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	hydrolase activity [GO:0016787]	cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]		cytoplasm [GO:0005737]		acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]	hydrolase activity [GO:0016787]
d1odsd__d3fytd___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	acetylesterase activity [GO:0008126]	cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]		cytoplasm [GO:0005737]		acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]	acetylesterase activity [GO:0008126]
d1odsf__d5iq0a___1			Firmicutes		cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	hydrolase activity [GO:0016787]	cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]		cytoplasm [GO:0005737]		acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]	hydrolase activity [GO:0016787]
d1odsg__d5iq2d___1			Firmicutes		cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	hydrolase activity [GO:0016787]	cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]		cytoplasm [GO:0005737]		acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]	hydrolase activity [GO:0016787]
d1odtc__d2xlbk___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	acetylesterase activity [GO:0008126]	cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]		cytoplasm [GO:0005737]		acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]	acetylesterase activity [GO:0008126]
d1odtc__d5ct6a___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	lipid catabolic process [GO:0016042]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d1odth__d2qtba2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1odua1_d4floa2__1			Thermotogae	Proteobacteria	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-L-fucosidase activity [GO:0004560]	amylosucrase activity [GO:0047669]
d1odwa__d1izib___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1odya__d3jvwb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1oe0c__d2j0qa1__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1oe1a2_d3rymd___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	nitrogen compound metabolic process [GO:0006807]			periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1oe3a1_d3t6wc2__1		Fungi	Proteobacteria	Basidiomycota	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	nitrogen compound metabolic process [GO:0006807]				copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1oe3a2_d1aspb2__1		Viridiplantae	Proteobacteria	Streptophyta	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	nitrogen compound metabolic process [GO:0006807]			extracellular region [GO:0005576]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]
d1oe4a__d3euga___1	Metazoa		Chordata	Proteobacteria	nucleus [GO:0005634]; DNA binding [GO:0003677]; single-strand selective uracil DNA N-glycosylase activity [GO:0017065]; base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	DNA binding [GO:0003677]; single-strand selective uracil DNA N-glycosylase activity [GO:0017065]	uracil DNA N-glycosylase activity [GO:0004844]
d1oe5a__d4wrza1__1	Metazoa		Chordata	Actinobacteria	nucleus [GO:0005634]; DNA binding [GO:0003677]; single-strand selective uracil DNA N-glycosylase activity [GO:0017065]; base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	DNA binding [GO:0003677]; single-strand selective uracil DNA N-glycosylase activity [GO:0017065]	uracil DNA N-glycosylase activity [GO:0004844]
d1oe5b__d4lylc1__1	Metazoa		Chordata		nucleus [GO:0005634]; DNA binding [GO:0003677]; single-strand selective uracil DNA N-glycosylase activity [GO:0017065]; base-excision repair [GO:0006284]		base-excision repair [GO:0006284]		nucleus [GO:0005634]		DNA binding [GO:0003677]; single-strand selective uracil DNA N-glycosylase activity [GO:0017065]	
d1oe6b__d3cxma___1	Metazoa		Chordata		nucleus [GO:0005634]; DNA binding [GO:0003677]; single-strand selective uracil DNA N-glycosylase activity [GO:0017065]; base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]	base-excision repair [GO:0006284]	base-excision repair [GO:0006284]	nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	DNA binding [GO:0003677]; single-strand selective uracil DNA N-glycosylase activity [GO:0017065]	uracil DNA N-glycosylase activity [GO:0004844]
d1oe7a2_d1oktb2__1	Metazoa		Platyhelminthes	Apicomplexa	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]					glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1oe8a2_d2khpa1__1	Metazoa		Platyhelminthes	Proteobacteria	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]; cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d1oela2_d1pf9k2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d1oemx__d5k25a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; transmembrane transporter activity [GO:0022857]; ion transport [GO:0006811]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	ion transport [GO:0006811]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	transmembrane transporter activity [GO:0022857]
d1oena2_d2zcic1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; gluconeogenesis [GO:0006094]	gluconeogenesis [GO:0006094]	gluconeogenesis [GO:0006094]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]	GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]
d1oena2_d4gmua1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	gluconeogenesis [GO:0006094]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]
d1oeqa4_d2wl6b1__1				Proteobacteria		cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]		poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1oeqb3_d1dm3b2__1				Proteobacteria		cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]		poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1oeqb3_d1u0vb1__1		Viridiplantae		Streptophyta		naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]		chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]				naringenin-chalcone synthase activity [GO:0016210]
d1oera3_d1x9eb1__1				Firmicutes		hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]		isoprenoid biosynthetic process [GO:0008299]				hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d1oera3_d2byzb1__1				Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1oerb3_d4ubtd2__1				Actinobacteria		acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]		cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]				acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d1oerb4_d3e60a1__1				Proteobacteria		beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]				beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1oerc3_d1u0uf1__1		Viridiplantae		Streptophyta		cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]		biosynthetic process [GO:0009058]		cytoplasm [GO:0005737]		pinosylvin synthase activity [GO:0050198]
d1oerc4_d5wx5d1__1		Viridiplantae		Streptophyta		transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]		biosynthetic process [GO:0009058]				transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1oerd3_d2rjtc2__1				Firmicutes		beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]				beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d1oerd3_d5bz4d2__1				Actinobacteria		transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]						transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1oerd4_d5ld8a2__1				Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]		fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]
d1of0a2_d1kbwa2__1			Firmicutes	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	sporulation resulting in formation of a cellular spore [GO:0030435]	nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]	cell outer membrane [GO:0009279]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1of0a3_d2q9ob3__1		Fungi	Firmicutes	Ascomycota	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	sporulation resulting in formation of a cellular spore [GO:0030435]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	outer membrane-bounded periplasmic space [GO:0030288]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1of0a3_d5b1ao2__1		Metazoa	Firmicutes	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	sporulation resulting in formation of a cellular spore [GO:0030435]	ATP synthesis coupled electron transport [GO:0042773]	outer membrane-bounded periplasmic space [GO:0030288]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1of2a2_d4l3cy1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1of6a__d3si9a1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1ofda3_d1ct9d2__1			Cyanobacteria	Proteobacteria	3 iron, 4 sulfur cluster binding [GO:0051538]; glutamate synthase (ferredoxin) activity [GO:0016041]; metal ion binding [GO:0046872]; glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; aspartate-ammonia ligase activity [GO:0004071]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; asparagine biosynthetic process [GO:0006529]; cellular amino acid biosynthetic process [GO:0008652]; cellular amino acid catabolic process [GO:0009063]; glutamine metabolic process [GO:0006541]; L-asparagine biosynthetic process [GO:0070981]	glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054]	asparagine biosynthetic process [GO:0006529]; cellular amino acid biosynthetic process [GO:0008652]; cellular amino acid catabolic process [GO:0009063]; glutamine metabolic process [GO:0006541]; L-asparagine biosynthetic process [GO:0070981]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	3 iron, 4 sulfur cluster binding [GO:0051538]; glutamate synthase (ferredoxin) activity [GO:0016041]; metal ion binding [GO:0046872]	amino acid binding [GO:0016597]; asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; aspartate-ammonia ligase activity [GO:0004071]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]
d1ofea3_d1ecfa2__1			Cyanobacteria	Proteobacteria	3 iron, 4 sulfur cluster binding [GO:0051538]; glutamate synthase (ferredoxin) activity [GO:0016041]; metal ion binding [GO:0046872]; glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	3 iron, 4 sulfur cluster binding [GO:0051538]; glutamate synthase (ferredoxin) activity [GO:0016041]; metal ion binding [GO:0046872]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]
d1offa__d1t3qa2__1			Cyanobacteria	Proteobacteria	cytosol [GO:0005829]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	oxidoreductase activity [GO:0016491]			cytosol [GO:0005829]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	oxidoreductase activity [GO:0016491]
d1ofhc__d2qmua3__1			Proteobacteria	Crenarchaeota	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	protein unfolding [GO:0043335]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	HslUV protease complex [GO:0009376]	cytosol [GO:0005829]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1ofja__d3bj2d___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ofna__d2gc2a2__1			Actinobacteria	Euryarchaeota	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]
d1ofnb__d1ep0a___1			Actinobacteria	Euryarchaeota	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]			dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d1ofs.2_d2vula___1	Viridiplantae		Streptophyta		mannose binding [GO:0005537]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d1ofua1_d2vxya1__1			Proteobacteria	Firmicutes	division septum assembly [GO:0000917]; negative regulation of cell division [GO:0051782]; SOS response [GO:0009432]	cell division site [GO:0032153]; cell septum [GO:0030428]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	division septum assembly [GO:0000917]; negative regulation of cell division [GO:0051782]; SOS response [GO:0009432]	cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]		cell division site [GO:0032153]; cell septum [GO:0030428]; cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1ofux__d1e1qa3__1		Metazoa	Proteobacteria	Chordata	division septum assembly [GO:0000917]; negative regulation of cell division [GO:0051782]; SOS response [GO:0009432]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	division septum assembly [GO:0000917]; negative regulation of cell division [GO:0051782]; SOS response [GO:0009432]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1ofza__d5mxca1__1	Fungi	Fungi	Ascomycota	Ascomycota	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d1og1a__d1og3a___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of plasma membrane [GO:0046658]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; NAD glycohydrolase activity [GO:0061810]; NAD(P)+-protein-arginine ADP-ribosyltransferase activity [GO:0003956]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD catabolic process [GO:0019677]; peptidyl-arginine ADP-ribosylation [GO:0018120]; protein ADP-ribosylation [GO:0006471]	anchored component of plasma membrane [GO:0046658]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; NAD glycohydrolase activity [GO:0061810]; NAD(P)+-protein-arginine ADP-ribosyltransferase activity [GO:0003956]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD catabolic process [GO:0019677]; peptidyl-arginine ADP-ribosylation [GO:0018120]; protein ADP-ribosylation [GO:0006471]	NAD catabolic process [GO:0019677]; peptidyl-arginine ADP-ribosylation [GO:0018120]; protein ADP-ribosylation [GO:0006471]	NAD catabolic process [GO:0019677]; peptidyl-arginine ADP-ribosylation [GO:0018120]; protein ADP-ribosylation [GO:0006471]	anchored component of plasma membrane [GO:0046658]	anchored component of plasma membrane [GO:0046658]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; NAD(P)+-protein-arginine ADP-ribosyltransferase activity [GO:0003956]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD glycohydrolase activity [GO:0061810]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; NAD(P)+-protein-arginine ADP-ribosyltransferase activity [GO:0003956]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD glycohydrolase activity [GO:0061810]
d1og2b__d1bu7a___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; (S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	(S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d1og5a__d3p3lb___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; (S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]		(S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1og6a__d1frba___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; cellular detoxification of aldehyde [GO:0110095]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; retinoid metabolic process [GO:0001523]		cellular detoxification of aldehyde [GO:0110095]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; retinoid metabolic process [GO:0001523]	cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	oxidoreductase activity [GO:0016491]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d1og6c__d2a79a___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; oxidoreductase activity [GO:0016491]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]		neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	cytosol [GO:0005829]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	oxidoreductase activity [GO:0016491]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]
d1og8a3_d3ov3a1__1		Viridiplantae		Streptophyta		curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]		flavonoid biosynthetic process [GO:0009813]				curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1og8a4_d2bz4c2__1				Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1og8b4_d3h78a1__1				Proteobacteria		cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]; fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]		fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]		cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]
d1og8c4_d5c1ja1__1				Proteobacteria		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]				3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1og8d4_d5bnsa1__1				Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1og9a3_d1hnja1__1				Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1og9b3_d4ubva1__1				Actinobacteria		acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]		cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]				acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d1og9b4_d2byyb1__1				Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1og9b4_d2wgea2__1				Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]		fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]
d1og9c3_d4japd2__1				Actinobacteria		polyketide synthase complex [GO:0034081]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		polyketide synthase complex [GO:0034081]		transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1og9c4_d2bz4a2__1				Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1og9d3_d2vbac2__1				Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1ogaa1_d4hful1__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]
d1ogaa2_d3c9na2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ogad1_d1yylh1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d1ogad1_d3vwjd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ogae2_d1boga1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ogcd__d3p12d___1			Firmicutes	Firmicutes	cytosol [GO:0005829]; intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; D-ribose catabolic process [GO:0019303]	cytosol [GO:0005829]; intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; D-ribose catabolic process [GO:0019303]	D-ribose catabolic process [GO:0019303]	D-ribose catabolic process [GO:0019303]	cytosol [GO:0005829]	cytosol [GO:0005829]	intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]	intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d1ogce__d2wcvd___1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; D-ribose catabolic process [GO:0019303]	cytoplasm [GO:0005737]; fucose binding [GO:0042806]; L-fucose mutarotase activity [GO:0036373]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; L-fucose metabolic process [GO:0042354]	D-ribose catabolic process [GO:0019303]	fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; L-fucose metabolic process [GO:0042354]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]	fucose binding [GO:0042806]; L-fucose mutarotase activity [GO:0036373]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]
d1ogdc__d2wcvb___1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; D-ribose catabolic process [GO:0019303]	cytoplasm [GO:0005737]; fucose binding [GO:0042806]; L-fucose mutarotase activity [GO:0036373]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; L-fucose metabolic process [GO:0042354]	D-ribose catabolic process [GO:0019303]	fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; L-fucose metabolic process [GO:0042354]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]	fucose binding [GO:0042806]; L-fucose mutarotase activity [GO:0036373]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]
d1ogia2_d1j9zb3__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	phycobilisome [GO:0030089]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1ogja2_d5vwaa2__1		Viridiplantae	Cyanobacteria	Streptophyta	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]	chloroplast [GO:0009507]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1ogmx1_d2z8ga1__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; dextranase activity [GO:0033904]; metabolic process [GO:0008152]	extracellular region [GO:0005576]; isopullulanase activity [GO:0051675]; metabolic process [GO:0008152]	metabolic process [GO:0008152]	metabolic process [GO:0008152]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	dextranase activity [GO:0033904]	isopullulanase activity [GO:0051675]
d1ogpd1_d3o7za1__1	Viridiplantae		Streptophyta		cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]		chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]		heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]	
d1ogpe1_d3iswa___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d1ogpf1_d1qvyc___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]
d1ogra6_d1e5yb___1				Proteobacteria		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1ogsa2_d1uh4a3__1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	extracellular region [GO:0005576]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1ogsb2_d1e4mm___1	Metazoa	Viridiplantae	Chordata	Streptophyta	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	vacuole [GO:0005773]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]
d1ogta1_d2bx5m___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ogta1_d2r9hd2__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1ogta2_d1t5wd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1ogtb1_d5cbab1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]
d1ogub2_d2i53a1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cyclin K-CDK12 complex [GO:0002944]; cyclin K-CDK13 complex [GO:0002945]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cell cycle arrest [GO:0071157]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues [GO:2001165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cell cycle arrest [GO:0071157]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues [GO:2001165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin K-CDK12 complex [GO:0002944]; cyclin K-CDK13 complex [GO:0002945]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]
d1ogud2_d3blhb1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1ogxa__d1gyba___1		Fungi	Proteobacteria	Ascomycota	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	cytoplasm [GO:0005737]; nuclear envelope [GO:0005635]; nuclear pore central transport channel [GO:0044613]; Ran GTPase binding [GO:0008536]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]	steroid metabolic process [GO:0008202]	nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606]		cytoplasm [GO:0005737]; nuclear envelope [GO:0005635]; nuclear pore central transport channel [GO:0044613]	steroid delta-isomerase activity [GO:0004769]	Ran GTPase binding [GO:0008536]
d1ogyc1_d3qq8a1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	anaerobic respiration [GO:0009061]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	periplasmic space [GO:0042597]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	metal ion binding [GO:0046872]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1ogyc2_d1vldm2__1			Proteobacteria		periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]		anaerobic respiration [GO:0009061]		periplasmic space [GO:0042597]		metal ion binding [GO:0046872]	
d1ogye2_d1ti2a2__1			Proteobacteria		periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]		anaerobic respiration [GO:0009061]		periplasmic space [GO:0042597]		metal ion binding [GO:0046872]	
d1ogyi1_d4koda1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	anaerobic respiration [GO:0009061]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	periplasmic space [GO:0042597]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	metal ion binding [GO:0046872]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1ogym1_d1e60a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	anaerobic respiration [GO:0009061]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]
d1ogym1_d3i9v34__1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	anaerobic respiration [GO:0009061]		periplasmic space [GO:0042597]	plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	quinone binding [GO:0048038]
d1ogyo1_d5ftjf1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	anaerobic respiration [GO:0009061]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	periplasmic space [GO:0042597]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	metal ion binding [GO:0046872]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1oh0a__d2gbwd___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]	steroid metabolic process [GO:0008202]	cellular aromatic compound metabolic process [GO:0006725]			steroid delta-isomerase activity [GO:0004769]	dioxygenase activity [GO:0051213]
d1oh0b__d5aewp___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	steroid metabolic process [GO:0008202]	aromatic compound catabolic process [GO:0019439]			steroid delta-isomerase activity [GO:0004769]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1oh3a__d5d21c___1	Fungi		Chytridiomycota	Proteobacteria		cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]		carbohydrate binding [GO:0030246]
d1oh7a4_d1wbda4__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; mismatch repair complex [GO:0032300]; adenine/cytosine mispair binding [GO:0032136]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA-dependent ATPase activity [GO:0008094]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]; cellular response to DNA damage stimulus [GO:0006974]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	cytosol [GO:0005829]; mismatch repair complex [GO:0032300]; adenine/cytosine mispair binding [GO:0032136]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA-dependent ATPase activity [GO:0008094]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]; cellular response to DNA damage stimulus [GO:0006974]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	cellular response to DNA damage stimulus [GO:0006974]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	cellular response to DNA damage stimulus [GO:0006974]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	cytosol [GO:0005829]; mismatch repair complex [GO:0032300]	cytosol [GO:0005829]; mismatch repair complex [GO:0032300]	adenine/cytosine mispair binding [GO:0032136]; ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA-dependent ATPase activity [GO:0008094]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]	adenine/cytosine mispair binding [GO:0032136]; ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA-dependent ATPase activity [GO:0008094]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]
d1oh9a__d2jjxa___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; cellular response to DNA damage stimulus [GO:0006974]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; UMP kinase activity [GO:0033862]; 'de novo' CTP biosynthetic process [GO:0044210]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; cellular response to DNA damage stimulus [GO:0006974]	'de novo' CTP biosynthetic process [GO:0044210]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]	ATP binding [GO:0005524]; UMP kinase activity [GO:0033862]
d1ohaa__d1uvda___1			Proteobacteria		cytoplasm [GO:0005737]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; cellular response to DNA damage stimulus [GO:0006974]		arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; cellular response to DNA damage stimulus [GO:0006974]		cytoplasm [GO:0005737]		acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]	
d1ohca2_d3smea___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cilium assembly [GO:0060271]; DNA repair [GO:0006281]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; mitotic cell cycle arrest [GO:0071850]; positive regulation of cytokinesis [GO:0032467]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cilium assembly [GO:0060271]; DNA repair [GO:0006281]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; mitotic cell cycle arrest [GO:0071850]; positive regulation of cytokinesis [GO:0032467]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1ohda1_d5k24a___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cilium assembly [GO:0060271]; DNA repair [GO:0006281]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; mitotic cell cycle arrest [GO:0071850]; positive regulation of cytokinesis [GO:0032467]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; transmembrane transporter activity [GO:0022857]; ion transport [GO:0006811]	cilium assembly [GO:0060271]; DNA repair [GO:0006281]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; mitotic cell cycle arrest [GO:0071850]; positive regulation of cytokinesis [GO:0032467]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	ion transport [GO:0006811]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	transmembrane transporter activity [GO:0022857]
d1ohda2_d3f81a___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cilium assembly [GO:0060271]; DNA repair [GO:0006281]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; mitotic cell cycle arrest [GO:0071850]; positive regulation of cytokinesis [GO:0032467]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	cytosol [GO:0005829]; immunological synapse [GO:0001772]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cytoskeletal protein binding [GO:0008092]; MAP kinase phosphatase activity [GO:0033549]; phosphatase activity [GO:0016791]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; receptor tyrosine kinase binding [GO:0030971]; cellular response to epidermal growth factor stimulus [GO:0071364]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of focal adhesion assembly [GO:0051893]	cilium assembly [GO:0060271]; DNA repair [GO:0006281]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; mitotic cell cycle arrest [GO:0071850]; positive regulation of cytokinesis [GO:0032467]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	cellular response to epidermal growth factor stimulus [GO:0071364]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of focal adhesion assembly [GO:0051893]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	cytosol [GO:0005829]; immunological synapse [GO:0001772]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	cytoskeletal protein binding [GO:0008092]; MAP kinase phosphatase activity [GO:0033549]; phosphatase activity [GO:0016791]; protein kinase binding [GO:0019901]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]
d1ohha1_d2rkwa2__1	Metazoa		Chordata	Euryarchaeota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1ohha1_d3ziaa3__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1ohhb2_d3oehf1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1ohhc2_d1efre2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1ohhd1_d5hkka3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1ohja__d3nrra1__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]
d1ohka__d1m78a___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d1ohqa__d5jnyb2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ohra__d5p1ca___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1ohrb__d1xdhb___1				Apicomplexa	aspartic-type endopeptidase activity [GO:0004190]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]				vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1ohrb__d4dqha___1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ohsa1_d4cdla___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	steroid metabolic process [GO:0008202]	steroid metabolic process [GO:0008202]			steroid delta-isomerase activity [GO:0004769]	steroid delta-isomerase activity [GO:0004769]
d1ohva__d1qira___1	Metazoa		Chordata	Proteobacteria	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1ohvc__d4azjb___1	Metazoa		Chordata	Firmicutes	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	L-serine biosynthetic process [GO:0006564]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]
d1ohvd__d5gvlc___1	Metazoa		Chordata	Apicomplexa	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d1ohya__d2bwnd___1	Metazoa		Chordata	Proteobacteria	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]; protoporphyrinogen IX biosynthetic process [GO:0006782]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	protoporphyrinogen IX biosynthetic process [GO:0006782]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]
d1ohyb__d5xmsa___1	Metazoa		Chordata	Apicomplexa	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d1ohza__d3p0de___1			Firmicutes		extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cell wall organization [GO:0071555]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]; cell wall organization [GO:0071555]		extracellular region [GO:0005576]		cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	
d1oi4a1_d4l95f___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; glyoxalase III activity [GO:0019172]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; protein deglycase activity [GO:0036524]; DNA repair [GO:0006281]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to pH [GO:0009268]; response to UV [GO:0009411]	vacuole [GO:0005773]; gamma-glutamyl-peptidase activity [GO:0034722]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]	DNA repair [GO:0006281]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to pH [GO:0009268]; response to UV [GO:0009411]	folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]	cytosol [GO:0005829]	vacuole [GO:0005773]	glyoxalase III activity [GO:0019172]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; protein deglycase activity [GO:0036524]	gamma-glutamyl-peptidase activity [GO:0034722]
d1oi4b1_d1ggja1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; glyoxalase III activity [GO:0019172]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; protein deglycase activity [GO:0036524]; DNA repair [GO:0006281]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to pH [GO:0009268]; response to UV [GO:0009411]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	DNA repair [GO:0006281]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to pH [GO:0009268]; response to UV [GO:0009411]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glyoxalase III activity [GO:0019172]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; protein deglycase activity [GO:0036524]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1oi6b__d2k9za___1			Actinobacteria	Thermotogae	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]						dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	
d1oi8a2_d3d03d___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	nucleotide catabolic process [GO:0009166]		outer membrane-bounded periplasmic space [GO:0030288]		5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1oi8b2_d2zoaa___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	nucleotide catabolic process [GO:0009166]		outer membrane-bounded periplasmic space [GO:0030288]		5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1oiaa__d2la4a1__1	Metazoa	Fungi	Chordata	Ascomycota	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleus [GO:0005634]; P-body [GO:0000932]; mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of mRNA stability [GO:0043488]; stress granule assembly [GO:0034063]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of mRNA stability [GO:0043488]; stress granule assembly [GO:0034063]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleus [GO:0005634]; P-body [GO:0000932]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]
d1oibb__d2q2cc___1			Proteobacteria	Firmicutes	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	membrane [GO:0016020]	phosphate ion binding [GO:0042301]	ligand-gated ion channel activity [GO:0015276]
d1oidb1_d4wwla2__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]	outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]	nucleotide catabolic process [GO:0009166]	nucleotide catabolic process [GO:0009166]	outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]
d1oila__d2j3da1__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	lipid catabolic process [GO:0016042]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	extracellular region [GO:0005576]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	acetylcholinesterase activity [GO:0003990]
d1oilb__d3g0bc2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1oiub2_d1vina1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]; cell cycle G1/S phase transition [GO:0044843]; cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle phase transition [GO:0044772]; protein phosphorylation [GO:0006468]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of DNA replication [GO:0006275]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell cycle G1/S phase transition [GO:0044843]; cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle phase transition [GO:0044772]; protein phosphorylation [GO:0006468]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of DNA replication [GO:0006275]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]
d1oizb1_d1auaa1__1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; cytosol [GO:0005829]; late endosome [GO:0005770]; lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin E binding [GO:0008431]; embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; lipid metabolic process [GO:0006629]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; phosphatidylcholine transporter activity [GO:0008525]; phosphatidylinositol transfer activity [GO:0008526]; ascospore formation [GO:0030437]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to vacuole transport [GO:0006896]; Golgi vesicle budding [GO:0048194]; negative regulation of phosphatidylcholine biosynthetic process [GO:2001246]; negative regulation of phosphatidylglycerol biosynthetic process [GO:1901352]; phosphatidylinositol metabolic process [GO:0046488]; phospholipid transport [GO:0015914]	embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; lipid metabolic process [GO:0006629]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]	ascospore formation [GO:0030437]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to vacuole transport [GO:0006896]; Golgi vesicle budding [GO:0048194]; negative regulation of phosphatidylcholine biosynthetic process [GO:2001246]; negative regulation of phosphatidylglycerol biosynthetic process [GO:1901352]; phosphatidylinositol metabolic process [GO:0046488]; phospholipid transport [GO:0015914]	cell [GO:0005623]; cytosol [GO:0005829]; late endosome [GO:0005770]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]	lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin E binding [GO:0008431]	phosphatidylcholine transporter activity [GO:0008525]; phosphatidylinositol transfer activity [GO:0008526]
d1oj6a__d5touk___1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; perikaryon [GO:0043204]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; apoptotic process [GO:0006915]; oxygen transport [GO:0015671]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	apoptotic process [GO:0006915]; oxygen transport [GO:0015671]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; perikaryon [GO:0043204]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1oj6c__d1uc3b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; perikaryon [GO:0043204]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; apoptotic process [GO:0006915]; oxygen transport [GO:0015671]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	apoptotic process [GO:0006915]; oxygen transport [GO:0015671]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; perikaryon [GO:0043204]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1oj8a__d1kh8a___1	Metazoa	Metazoa	Chordata	Chordata	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]				extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1oj9a2_d1kifc2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d1oj9b2_d3qseb2__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	tetrahydrofolate metabolic process [GO:0046653]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	sarcosine oxidase activity [GO:0008115]
d1ojaa2_d1ddoe2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d1ojbb4_d1kifh2__1		Metazoa		Chordata		cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]		D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]		cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]		D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d1ojca2_d1an9b2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d1ojda2_d1ryid2__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]; cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]
d1ojdc2_d1el7b2__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	tetrahydrofolate metabolic process [GO:0046653]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	sarcosine oxidase activity [GO:0008115]
d1ojdc2_d1o5wa2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	integral component of membrane [GO:0016021]; mitochondrial outer membrane [GO:0005741]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; serotonin binding [GO:0051378]; catecholamine catabolic process [GO:0042424]; neurotransmitter catabolic process [GO:0042135]; phenylethylamine metabolic process [GO:0042443]; serotonin metabolic process [GO:0042428]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	catecholamine catabolic process [GO:0042424]; neurotransmitter catabolic process [GO:0042135]; phenylethylamine metabolic process [GO:0042443]; serotonin metabolic process [GO:0042428]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial outer membrane [GO:0005741]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; serotonin binding [GO:0051378]
d1ojdf2_d2gb0b2__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	tetrahydrofolate metabolic process [GO:0046653]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	sarcosine oxidase activity [GO:0008115]
d1ojdh2_d1ve9b2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d1ojja__d3pfxa___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		cellulase activity [GO:0008810]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1ojjb__d1qh7b___1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		cellulase activity [GO:0008810]	endo-1,4-beta-xylanase activity [GO:0031176]
d1ojka__d1ms4b1__1	Fungi		Ascomycota		extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	cellulose catabolic process [GO:0030245]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]		cellulase activity [GO:0008810]	exo-alpha-sialidase activity [GO:0004308]
d1ojka__d2ovwa___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		cellulase activity [GO:0008810]	cellulase activity [GO:0008810]
d1ojma1_d1rwca1__1			Firmicutes	Actinobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]
d1ojma1_d4e1ya1__1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	periplasmic space [GO:0042597]; lyase activity [GO:0016829]	carbohydrate metabolic process [GO:0005975]		cell wall [GO:0005618]; extracellular region [GO:0005576]	periplasmic space [GO:0042597]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	lyase activity [GO:0016829]
d1ojma3_d3iaqb5__1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	cell wall [GO:0005618]; extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1ojna1_d2e22a1__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	carbohydrate metabolic process [GO:0005975]	polysaccharide metabolic process [GO:0005976]	cell wall [GO:0005618]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]
d1ojna3_d3ejqa3__1		Metazoa	Firmicutes	Arthropoda	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	cell wall [GO:0005618]; extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1ojoa1_d3evla1__1			Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		cell wall [GO:0005618]; extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	
d1ojua3_d1up6g1__1				Thermotogae		6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d1ojua3_d2iypc1__1				Firmicutes		NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]		D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]				NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]
d1ojua4_d3hhpa2__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]		L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]
d1ojxc__d4u4ma___1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; 2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]; aldonic acid catabolic process [GO:0046176]	glycolytic process [GO:0006096]	aldonic acid catabolic process [GO:0046176]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]
d1ojxc__d6aldb___1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]	I band [GO:0031674]; M band [GO:0031430]	fructose-bisphosphate aldolase activity [GO:0004332]	fructose-bisphosphate aldolase activity [GO:0004332]
d1ojxd__d3pb2a1__1			Crenarchaeota	Thermotogae	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycolytic process [GO:0006096]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1ojxg__d5c5yb___1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	glycolytic process [GO:0006096]	deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	deoxyribose-phosphate aldolase activity [GO:0004139]
d1ok4a__d4e38c1__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		fructose-bisphosphate aldolase activity [GO:0004332]	4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]
d1ok4d__d2v8zc___1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; 2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]; aldonic acid catabolic process [GO:0046176]	glycolytic process [GO:0006096]	aldonic acid catabolic process [GO:0046176]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]
d1ok8a1_d5vigz___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	
d1okba__d2booa___1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d1okba__d2uuga___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d1okbb__d4ws6a1__1	Metazoa		Chordata	Actinobacteria	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d1okib2_d2nbra___1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d1okja1_d3m3za2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d1okjc2_d3gl1a1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; polysome [GO:0005844]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; calmodulin binding [GO:0005516]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; 'de novo' cotranslational protein folding [GO:0051083]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; cytoplasmic translation [GO:0002181]; protein refolding [GO:0042026]; regulation of translational fidelity [GO:0006450]; response to unfolded protein [GO:0006986]; ribosomal subunit export from nucleus [GO:0000054]; rRNA processing [GO:0006364]; translational frameshifting [GO:0006452]; translational termination [GO:0006415]; vesicle-mediated transport [GO:0016192]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	'de novo' cotranslational protein folding [GO:0051083]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; cytoplasmic translation [GO:0002181]; protein refolding [GO:0042026]; regulation of translational fidelity [GO:0006450]; response to unfolded protein [GO:0006986]; ribosomal subunit export from nucleus [GO:0000054]; rRNA processing [GO:0006364]; translational frameshifting [GO:0006452]; translational termination [GO:0006415]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; polysome [GO:0005844]	identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d1okjd1_d5gn6d2__1			Proteobacteria		cytosol [GO:0005829]; identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d1okjd2_d2a6aa2__1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	cytoplasm [GO:0005737]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]	
d1okjd2_d3goia2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]
d1okka1_d1qzwc1__1			Deinococcus-Thermus	Crenarchaeota	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]	signal recognition particle [GO:0048500]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1okqa1_d1cn1a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]		basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]		signaling receptor binding [GO:0005102]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1okqa2_d1jn2p___1	Metazoa	Viridiplantae	Chordata	Streptophyta	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]		basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]		signaling receptor binding [GO:0005102]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1okqa2_d3v64b___1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	cell surface [GO:0009986]; dendrite [GO:0030425]; integral component of membrane [GO:0016021]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; apolipoprotein binding [GO:0034185]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; receptor tyrosine kinase binding [GO:0030971]; scaffold protein binding [GO:0097110]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	cell surface [GO:0009986]; dendrite [GO:0030425]; integral component of membrane [GO:0016021]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]	signaling receptor binding [GO:0005102]	apolipoprotein binding [GO:0034185]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; receptor tyrosine kinase binding [GO:0030971]; scaffold protein binding [GO:0097110]
d1okta1_d2ntoa2__1			Apicomplexa	Proteobacteria	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]				cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1okta1_d4yh2c2__1		Metazoa	Apicomplexa	Arthropoda	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]		glutathione metabolic process [GO:0006749]		cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1oktb1_d1bx9a1__1		Viridiplantae	Apicomplexa	Streptophyta	glutathione transferase activity [GO:0004364]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	glutathione transferase activity [GO:0004364]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d1oktb1_d2hqtb___1		Fungi	Apicomplexa	Ascomycota	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]; enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]; positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]		positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]	glutathione transferase activity [GO:0004364]	enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]
d1oktb2_d2i81e___1			Apicomplexa	Apicomplexa	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]	glutathione transferase activity [GO:0004364]	peroxiredoxin activity [GO:0051920]
d1okub4_d2wxvd1__1		Metazoa		Chordata		Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]		anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]		Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]		ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1okva__d2biya___1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]
d1okwb1_d2g9xb2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1okwb2_d2i40d1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1okxb__d2ijd21__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ol1d1_d1h26b2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1ol1d2_d5efqd1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cyclin K-CDK12 complex [GO:0002944]; cyclin K-CDK13 complex [GO:0002945]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cell cycle arrest [GO:0071157]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues [GO:2001165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cell cycle arrest [GO:0071157]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues [GO:2001165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin K-CDK12 complex [GO:0002944]; cyclin K-CDK13 complex [GO:0002945]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]
d1olca__d5loma___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	protein transport [GO:0015031]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	membrane [GO:0016020]	peptide transmembrane transporter activity [GO:1904680]	ligand-gated ion channel activity [GO:0015276]
d1olla1_d1t89c2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; SWI/SNF complex [GO:0016514]; cellular defense response [GO:0006968]; natural killer cell activation [GO:0030101]; regulation of immune response [GO:0050776]; regulation of natural killer cell mediated cytotoxicity [GO:0042269]; signal transduction [GO:0007165]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cellular defense response [GO:0006968]; natural killer cell activation [GO:0030101]; regulation of immune response [GO:0050776]; regulation of natural killer cell mediated cytotoxicity [GO:0042269]; signal transduction [GO:0007165]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; SWI/SNF complex [GO:0016514]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1olma3_d4uyba2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phospholipid binding [GO:0005543]; vitamin E binding [GO:0008431]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cholesterol biosynthetic process [GO:0045540]	extracellular exosome [GO:0070062]; lipid binding [GO:0008289]	positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cholesterol biosynthetic process [GO:0045540]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]	phospholipid binding [GO:0005543]; vitamin E binding [GO:0008431]	lipid binding [GO:0008289]
d1olmc3_d3w68a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phospholipid binding [GO:0005543]; vitamin E binding [GO:0008431]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cholesterol biosynthetic process [GO:0045540]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; late endosome [GO:0005770]; lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin binding [GO:0019842]; vitamin E binding [GO:0008431]; embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; placenta development [GO:0001890]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]	positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cholesterol biosynthetic process [GO:0045540]	embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; placenta development [GO:0001890]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; late endosome [GO:0005770]	phospholipid binding [GO:0005543]; vitamin E binding [GO:0008431]	lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin binding [GO:0019842]; vitamin E binding [GO:0008431]
d1olpb2_d1rrla2__1		Viridiplantae	Firmicutes	Streptophyta	phospholipase C activity [GO:0004629]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; oxylipin biosynthetic process [GO:0031408]		oxylipin biosynthetic process [GO:0031408]		cytoplasm [GO:0005737]	phospholipase C activity [GO:0004629]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d1olpb2_d2wxta2__1			Firmicutes	Firmicutes	phospholipase C activity [GO:0004629]; zinc ion binding [GO:0008270]	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]		hemolysis in other organism [GO:0044179]		extracellular region [GO:0005576]	phospholipase C activity [GO:0004629]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1olpc1_d5fbaa___1		Fungi	Firmicutes	Ascomycota	phospholipase C activity [GO:0004629]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleic acid binding [GO:0003676]; DNA catabolic process [GO:0006308]		DNA catabolic process [GO:0006308]			phospholipase C activity [GO:0004629]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleic acid binding [GO:0003676]
d1olqa__d1q8ob___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	polysaccharide catabolic process [GO:0000272]				cellulase activity [GO:0008810]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1olra__d1h4ha___1	Fungi		Ascomycota	Firmicutes	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]			cellulase activity [GO:0008810]	endo-1,4-beta-xylanase activity [GO:0031176]
d1olsb2_d3lq2b3__1	Metazoa		Chordata	Proteobacteria	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	metal ion binding [GO:0046872]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]		3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	metal ion binding [GO:0046872]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1olxb2_d1ay0a3__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	pentose-phosphate shunt [GO:0006098]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1om0a__d5dt7d___1	Viridiplantae		Streptophyta	Firmicutes	extracellular region [GO:0005576]; enzyme inhibitor activity [GO:0004857]; carbohydrate metabolic process [GO:0005975]; defense response to fungus [GO:0050832]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]; defense response to fungus [GO:0050832]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		enzyme inhibitor activity [GO:0004857]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1om3h1_d4fp8m2__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d1om3k1_d5gs1g1__1												
d1om3l1_d1qnzh___1		Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		
d1om3m1_d2feco1__1				Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1omib1_d1j59b2__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; pathogenesis [GO:0009405]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	pathogenesis [GO:0009405]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d1on3f2_d3mt6f___1			Actinobacteria	Proteobacteria	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	fatty acid biosynthetic process [GO:0006633]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	acetyl-CoA carboxylase complex [GO:0009317]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	acetyl-CoA carboxylase activity [GO:0003989]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1on7a__d1xzvd___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1on7b__d3oo4a___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1on9b1_d1szoa___1			Actinobacteria	Actinobacteria	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]; fatty acid biosynthetic process [GO:0006633]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	fatty acid biosynthetic process [GO:0006633]		acetyl-CoA carboxylase complex [GO:0009317]		acetyl-CoA carboxylase activity [GO:0003989]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]
d1on9c1_d1xo6f2__1			Actinobacteria	Actinobacteria	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]; fatty acid biosynthetic process [GO:0006633]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	acetyl-CoA carboxylase complex [GO:0009317]	acetyl-CoA carboxylase complex [GO:0009317]	acetyl-CoA carboxylase activity [GO:0003989]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]
d1on9f2_d3t88c___1			Actinobacteria	Proteobacteria	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; bicarbonate binding [GO:0071890]; menaquinone biosynthetic process [GO:0009234]	fatty acid biosynthetic process [GO:0006633]	menaquinone biosynthetic process [GO:0009234]	acetyl-CoA carboxylase complex [GO:0009317]	cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]	1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; bicarbonate binding [GO:0071890]
d1oneb2_d2ggef2__1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d1onia__d1jd1b___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]; deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; L-threonine catabolic process to glycine [GO:0019518]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; L-threonine catabolic process to glycine [GO:0019518]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	organonitrogen compound catabolic process [GO:1901565]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	deaminase activity [GO:0019239]
d1onib__d1comd___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]; deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; L-threonine catabolic process to glycine [GO:0019518]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; L-threonine catabolic process to glycine [GO:0019518]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]	cytoplasm [GO:0005737]	deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	chorismate mutase activity [GO:0004106]
d1onkb1_d5bp5b1__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]				carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	
d1onkb2_d2d24b2__1	Viridiplantae		Streptophyta	Actinobacteria	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	endo-1,4-beta-xylanase activity [GO:0031176]
d1onpb3_d3cmco2__1			Proteobacteria	Firmicutes	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1onqb__d2agjh1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1onqd__d1ezvy___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1onya__d3blta___1	Metazoa		Chordata	Proteobacteria	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	pathogenesis [GO:0009405]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	extracellular region [GO:0005576]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	protein tyrosine phosphatase activity [GO:0004725]
d1oo0b__d4f26a___1	Metazoa	Metazoa	Arthropoda	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; exon-exon junction complex [GO:0035145]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; establishment of pole plasm mRNA localization [GO:0046595]; germarium-derived oocyte fate determination [GO:0007294]; microtubule cytoskeleton organization [GO:0000226]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of transposition, DNA-mediated [GO:0000335]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte dorsal/ventral axis specification [GO:0007310]; oocyte nucleus localization involved in oocyte dorsal/ventral axis specification [GO:0051663]; pole plasm oskar mRNA localization [GO:0045451]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of pole plasm oskar mRNA localization [GO:0007317]; RNA splicing [GO:0008380]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	establishment of pole plasm mRNA localization [GO:0046595]; germarium-derived oocyte fate determination [GO:0007294]; microtubule cytoskeleton organization [GO:0000226]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of transposition, DNA-mediated [GO:0000335]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte dorsal/ventral axis specification [GO:0007310]; oocyte nucleus localization involved in oocyte dorsal/ventral axis specification [GO:0051663]; pole plasm oskar mRNA localization [GO:0045451]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of pole plasm oskar mRNA localization [GO:0007317]; RNA splicing [GO:0008380]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; exon-exon junction complex [GO:0035145]; nucleus [GO:0005634]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	mRNA binding [GO:0003729]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]
d1oo2a__d3i9pa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; thyroid hormone binding [GO:0070324]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	extracellular region [GO:0005576]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1oo2c__d3iwuc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; thyroid hormone binding [GO:0070324]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	extracellular region [GO:0005576]	peroxisome [GO:0005777]	thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1oo3a__d1cj1d___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; insulin-like growth factor receptor binding [GO:0005159]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; growth hormone receptor signaling pathway [GO:0060396]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; growth hormone receptor signaling pathway [GO:0060396]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]
d1oo3a__d4ohlb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; insulin-like growth factor receptor binding [GO:0005159]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; growth hormone receptor signaling pathway [GO:0060396]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]; abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; growth hormone receptor signaling pathway [GO:0060396]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]	cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]
d1oo6b__d5hdja___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; 6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]; 2,4,6-trinitrotoluene catabolic process [GO:0046256]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	2,4,6-trinitrotoluene catabolic process [GO:0046256]		cytosol [GO:0005829]; membrane [GO:0016020]		6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1ooaa1_d2d0fa1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1ooab1_d2x6aa2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; regulation of ion transmembrane transport [GO:0034765]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	regulation of ion transmembrane transport [GO:0034765]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	integral component of membrane [GO:0016021]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]
d1ooab1_d3jv6a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d1ooab2_d1le5e2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1ooca__d1plua___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	pectin catabolic process [GO:0045490]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]
d1oocb__d2nt9a___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	pectin catabolic process [GO:0045490]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]
d1ooga__d2l2ca___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	odorant binding [GO:0005549]	courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]		dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]	odorant binding [GO:0005549]
d1ooga__d3b86a___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]	dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]
d1oogb__d1orgb___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	odorant binding [GO:0005549]	courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]		dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]	odorant binding [GO:0005549]
d1oohb1_d2kpha___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	odorant binding [GO:0005549]	courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]		dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]	odorant binding [GO:0005549]
d1oohb1_d4f7fa___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]	courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]	dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]
d1ook.1_d3prob___1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	serine-type endopeptidase activity [GO:0004252]
d1oopa__d1ncrc___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ooza2_d2ahwc2__1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	acetate CoA-transferase activity [GO:0008775]; ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]	mitochondrion [GO:0005739]		3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	acetate CoA-transferase activity [GO:0008775]
d1ooza2_d3oxoh2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]
d1oozb2_d1t5oa1__1	Metazoa		Chordata	Euryarchaeota	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	S-methyl-5-thioribose-1-phosphate isomerase activity [GO:0046523]; L-methionine salvage from S-adenosylmethionine [GO:0019284]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	L-methionine salvage from S-adenosylmethionine [GO:0019284]	mitochondrion [GO:0005739]		3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	S-methyl-5-thioribose-1-phosphate isomerase activity [GO:0046523]
d1op0a__d1rd3.2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]		acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d1op1a__d2ftua1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cis-Golgi network [GO:0005801]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; rough endoplasmic reticulum lumen [GO:0048237]; amyloid-beta binding [GO:0001540]; heparin binding [GO:0008201]; lipase binding [GO:0035473]; low-density lipoprotein particle receptor binding [GO:0050750]; receptor antagonist activity [GO:0048019]; signaling receptor binding [GO:0005102]; very-low-density lipoprotein particle receptor binding [GO:0070326]; amyloid-beta clearance by transcytosis [GO:0150093]; extracellular negative regulation of signal transduction [GO:1900116]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of cell death [GO:0060548]; negative regulation of protein binding [GO:0032091]; negative regulation of receptor internalization [GO:0002091]; negative regulation of very-low-density lipoprotein particle clearance [GO:0010916]; positive regulation of amyloid-beta clearance [GO:1900223]; regulation of receptor-mediated endocytosis [GO:0048259]	cell surface [GO:0009986]; cis-Golgi network [GO:0005801]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; rough endoplasmic reticulum lumen [GO:0048237]; amyloid-beta binding [GO:0001540]; heparin binding [GO:0008201]; lipase binding [GO:0035473]; low-density lipoprotein particle receptor binding [GO:0050750]; receptor antagonist activity [GO:0048019]; signaling receptor binding [GO:0005102]; very-low-density lipoprotein particle receptor binding [GO:0070326]; amyloid-beta clearance by transcytosis [GO:0150093]; extracellular negative regulation of signal transduction [GO:1900116]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of cell death [GO:0060548]; negative regulation of protein binding [GO:0032091]; negative regulation of receptor internalization [GO:0002091]; negative regulation of very-low-density lipoprotein particle clearance [GO:0010916]; positive regulation of amyloid-beta clearance [GO:1900223]; regulation of receptor-mediated endocytosis [GO:0048259]	amyloid-beta clearance by transcytosis [GO:0150093]; extracellular negative regulation of signal transduction [GO:1900116]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of cell death [GO:0060548]; negative regulation of protein binding [GO:0032091]; negative regulation of receptor internalization [GO:0002091]; negative regulation of very-low-density lipoprotein particle clearance [GO:0010916]; positive regulation of amyloid-beta clearance [GO:1900223]; regulation of receptor-mediated endocytosis [GO:0048259]	amyloid-beta clearance by transcytosis [GO:0150093]; extracellular negative regulation of signal transduction [GO:1900116]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of cell death [GO:0060548]; negative regulation of protein binding [GO:0032091]; negative regulation of receptor internalization [GO:0002091]; negative regulation of very-low-density lipoprotein particle clearance [GO:0010916]; positive regulation of amyloid-beta clearance [GO:1900223]; regulation of receptor-mediated endocytosis [GO:0048259]	cell surface [GO:0009986]; cis-Golgi network [GO:0005801]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; rough endoplasmic reticulum lumen [GO:0048237]	cell surface [GO:0009986]; cis-Golgi network [GO:0005801]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; rough endoplasmic reticulum lumen [GO:0048237]	amyloid-beta binding [GO:0001540]; heparin binding [GO:0008201]; lipase binding [GO:0035473]; low-density lipoprotein particle receptor binding [GO:0050750]; receptor antagonist activity [GO:0048019]; signaling receptor binding [GO:0005102]; very-low-density lipoprotein particle receptor binding [GO:0070326]	amyloid-beta binding [GO:0001540]; heparin binding [GO:0008201]; lipase binding [GO:0035473]; low-density lipoprotein particle receptor binding [GO:0050750]; receptor antagonist activity [GO:0048019]; signaling receptor binding [GO:0005102]; very-low-density lipoprotein particle receptor binding [GO:0070326]
d1op3k1_d5sv3a___1		Viridiplantae		Streptophyta		endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1op3k2_d5w1wn2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1op3l1_d1e4wh1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1op3l2_d1s7re___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1op5k1_d2gfbo2__1												
d1op8a__d1vcqa___1	Metazoa		Chordata		extracellular region [GO:0005576]; immunological synapse [GO:0001772]; nucleus [GO:0005634]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; immune response [GO:0006955]; negative regulation of DNA binding [GO:0043392]; negative regulation of endodeoxyribonuclease activity [GO:0032078]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to bacterium [GO:0009617]	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; immune response [GO:0006955]; negative regulation of DNA binding [GO:0043392]; negative regulation of endodeoxyribonuclease activity [GO:0032078]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to bacterium [GO:0009617]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; immunological synapse [GO:0001772]; nucleus [GO:0005634]	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1op8b__d1qtfa___1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; immunological synapse [GO:0001772]; nucleus [GO:0005634]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; immune response [GO:0006955]; negative regulation of DNA binding [GO:0043392]; negative regulation of endodeoxyribonuclease activity [GO:0032078]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to bacterium [GO:0009617]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; immune response [GO:0006955]; negative regulation of DNA binding [GO:0043392]; negative regulation of endodeoxyribonuclease activity [GO:0032078]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to bacterium [GO:0009617]		extracellular region [GO:0005576]; immunological synapse [GO:0001772]; nucleus [GO:0005634]		protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]
d1op8e__d1gdna___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular region [GO:0005576]; immunological synapse [GO:0001772]; nucleus [GO:0005634]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; immune response [GO:0006955]; negative regulation of DNA binding [GO:0043392]; negative regulation of endodeoxyribonuclease activity [GO:0032078]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to bacterium [GO:0009617]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; immune response [GO:0006955]; negative regulation of DNA binding [GO:0043392]; negative regulation of endodeoxyribonuclease activity [GO:0032078]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to bacterium [GO:0009617]		extracellular region [GO:0005576]; immunological synapse [GO:0001772]; nucleus [GO:0005634]	extracellular region [GO:0005576]	protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1opbb__d5kicb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol metabolic process [GO:0042572]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	retinol metabolic process [GO:0042572]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	retinal binding [GO:0016918]; retinol binding [GO:0019841]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1opbd__d1ngla___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol metabolic process [GO:0042572]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	retinol metabolic process [GO:0042572]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	retinal binding [GO:0016918]; retinol binding [GO:0019841]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1opca__d2feza1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; GTPase activity [GO:0003924]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	ATPase activity [GO:0016887]; DNA binding [GO:0003677]; GTPase activity [GO:0003924]
d1opeb2_d5ddka1__1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	mitochondrion [GO:0005739]		3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d1opgh1_d5ukol2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1opgl1_d4bsva2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1opla2_d1o4qa___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]
d1opma1_d1pnga2__1	Metazoa		Chordata	Bacteroidetes	cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]; central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]	central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]		cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]
d1oq4c__d1fz5c___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	fatty acid biosynthetic process [GO:0006633]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	chloroplast [GO:0009507]		acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1oq4f__d3ghqd___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	fatty acid biosynthetic process [GO:0006633]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	chloroplast [GO:0009507]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1oq5a__d4wr7b___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]
d1oq7d__d2jd72___1	Viridiplantae		Streptophyta	Euryarchaeota	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	chloroplast [GO:0009507]	cell [GO:0005623]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]	ferric iron binding [GO:0008199]
d1oqbc__d3n38a___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	fatty acid biosynthetic process [GO:0006633]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1oqbd__d1xmfd___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	fatty acid biosynthetic process [GO:0006633]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	chloroplast [GO:0009507]		acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1oqbd__d4cmyj___1	Viridiplantae		Streptophyta	Chlorobi	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	chloroplast [GO:0009507]	cell [GO:0005623]; cytoplasm [GO:0005737]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]	ferric iron binding [GO:0008199]
d1oqbe__d3pvyc1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	fatty acid biosynthetic process [GO:0006633]	phenylacetate catabolic process [GO:0010124]	chloroplast [GO:0009507]	cytosol [GO:0005829]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]	
d1oqbf__d3hx2r___1	Viridiplantae		Streptophyta		chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		chloroplast [GO:0009507]		acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]	
d1oqca__d3o55a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]; cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573]; response to lipopolysaccharide [GO:0032496]	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573]; response to lipopolysaccharide [GO:0032496]		cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]
d1oqcb__d3w4yb1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]; cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; protein import into mitochondrial intermembrane space [GO:0045041]	cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573]; response to lipopolysaccharide [GO:0032496]	cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; protein import into mitochondrial intermembrane space [GO:0045041]	cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	cell [GO:0005623]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]
d1oqcd__d3w4ya___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]; cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; protein import into mitochondrial intermembrane space [GO:0045041]	cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573]; response to lipopolysaccharide [GO:0032496]	cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; protein import into mitochondrial intermembrane space [GO:0045041]	cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	cell [GO:0005623]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]
d1oqda__d5hkja3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	blood microparticle [GO:0072562]; cell [GO:0005623]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; postsynapse [GO:0098794]; synapse [GO:0045202]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; regulation of complement activation [GO:0030449]; synapse pruning [GO:0098883]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; regulation of complement activation [GO:0030449]; synapse pruning [GO:0098883]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; postsynapse [GO:0098794]; synapse [GO:0045202]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	
d1oqde__d3b93a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor superfamily binding [GO:0032813]; adaptive immune response [GO:0002250]; cell-cell signaling [GO:0007267]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell adhesion [GO:0045785]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of T cell proliferation [GO:0042129]; signal transduction [GO:0007165]; T cell proliferation involved in immune response [GO:0002309]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	adaptive immune response [GO:0002250]; cell-cell signaling [GO:0007267]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell adhesion [GO:0045785]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of T cell proliferation [GO:0042129]; signal transduction [GO:0007165]; T cell proliferation involved in immune response [GO:0002309]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor superfamily binding [GO:0032813]
d1oqdh__d3me2a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine binding [GO:0019955]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]; tumor necrosis factor-activated receptor activity [GO:0005031]; adaptive immune response [GO:0002250]; circadian temperature homeostasis [GO:0060086]; lymph node development [GO:0048535]; mammary gland alveolus development [GO:0060749]; multicellular organism development [GO:0007275]; multinuclear osteoclast differentiation [GO:0072674]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of bone resorption [GO:0045780]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling [GO:0071848]; positive regulation of fever generation by positive regulation of prostaglandin secretion [GO:0071812]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; response to cytokine [GO:0034097]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to radiation [GO:0009314]; response to tumor necrosis factor [GO:0034612]; TNFSF11-mediated signaling pathway [GO:0071847]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	adaptive immune response [GO:0002250]; circadian temperature homeostasis [GO:0060086]; lymph node development [GO:0048535]; mammary gland alveolus development [GO:0060749]; multicellular organism development [GO:0007275]; multinuclear osteoclast differentiation [GO:0072674]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of bone resorption [GO:0045780]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling [GO:0071848]; positive regulation of fever generation by positive regulation of prostaglandin secretion [GO:0071812]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; response to cytokine [GO:0034097]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to radiation [GO:0009314]; response to tumor necrosis factor [GO:0034612]; TNFSF11-mediated signaling pathway [GO:0071847]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	cytokine binding [GO:0019955]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]; tumor necrosis factor-activated receptor activity [GO:0005031]
d1oqea__d1a8mc___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]		cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d1oqeb__d5kc6a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic membrane [GO:0045211]; synaptic cleft [GO:0043083]; protein homodimerization activity [GO:0042803]; cerebellar granule cell differentiation [GO:0021707]; chemical synaptic transmission [GO:0007268]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of excitatory postsynaptic potential [GO:0090394]; nervous system development [GO:0007399]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; protein secretion [GO:0009306]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]	adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cerebellar granule cell differentiation [GO:0021707]; chemical synaptic transmission [GO:0007268]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of excitatory postsynaptic potential [GO:0090394]; nervous system development [GO:0007399]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; protein secretion [GO:0009306]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic membrane [GO:0045211]; synaptic cleft [GO:0043083]		protein homodimerization activity [GO:0042803]
d1oqec__d2wnvc___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	blood microparticle [GO:0072562]; cell [GO:0005623]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; postsynapse [GO:0098794]; synapse [GO:0045202]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; regulation of complement activation [GO:0030449]; synapse pruning [GO:0098883]	adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; regulation of complement activation [GO:0030449]; synapse pruning [GO:0098883]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; postsynapse [GO:0098794]; synapse [GO:0045202]		
d1oqef__d5h4ca___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	extracellular space [GO:0005615]; protein secretion [GO:0009306]	adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	protein secretion [GO:0009306]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]		
d1oqeh__d4qqld___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	collagen trimer [GO:0005581]; extracellular region [GO:0005576]; identical protein binding [GO:0042802]; regulation of synapse organization [GO:0050807]	adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	regulation of synapse organization [GO:0050807]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	collagen trimer [GO:0005581]; extracellular region [GO:0005576]		identical protein binding [GO:0042802]
d1oqei__d5h49a___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic membrane [GO:0045211]; synaptic cleft [GO:0043083]; protein homodimerization activity [GO:0042803]; cerebellar granule cell differentiation [GO:0021707]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of excitatory postsynaptic potential [GO:0090394]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; protein secretion [GO:0009306]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]	adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cerebellar granule cell differentiation [GO:0021707]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of excitatory postsynaptic potential [GO:0090394]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; protein secretion [GO:0009306]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic membrane [GO:0045211]; synaptic cleft [GO:0043083]		protein homodimerization activity [GO:0042803]
d1oqha__d2xx8a___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1oqla__d3mvga___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1oqmb__d1fgxa___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1oqmb__d1k4va___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d1oqmd__d5idta___1	Metazoa		Chordata	Proteobacteria	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; extracellular polysaccharide biosynthetic process [GO:0045226]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	extracellular polysaccharide biosynthetic process [GO:0045226]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]		alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]
d1oqoa1_d1dn2b2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1oqoa2_d1efxa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1oqoa2_d3upcc___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1oqob1_d5o0wh1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	glycolytic process [GO:0006096]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	fructose-bisphosphate aldolase activity [GO:0004332]
d1oqob2_d1tjhh1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	structural molecule activity [GO:0005198]
d1oqob2_d4pjeh2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1oqpa1_d1eh2a___1	Fungi	Metazoa	Ascomycota	Chordata	endoplasmic reticulum [GO:0005783]; half bridge of spindle pole body [GO:0005825]; microtubule [GO:0005874]; cell division [GO:0051301]; karyogamy involved in conjugation with cellular fusion [GO:0000742]; spindle pole body duplication [GO:0030474]	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]; clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	cell division [GO:0051301]; karyogamy involved in conjugation with cellular fusion [GO:0000742]; spindle pole body duplication [GO:0030474]	clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	endoplasmic reticulum [GO:0005783]; half bridge of spindle pole body [GO:0005825]; microtubule [GO:0005874]	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]		cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]
d1oqrc__d5la3b1__1			Proteobacteria	Firmicutes	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]
d1oqsc__d1le6c___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipase activity [GO:0004620]; arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; axon guidance [GO:0007411]; cellular response to leukemia inhibitory factor [GO:1990830]; cholesterol homeostasis [GO:0042632]; lipid catabolic process [GO:0016042]; lysophospholipid transport [GO:0051977]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of prostaglandin secretion [GO:0032308]; regulation of macrophage activation [GO:0043030]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; axon guidance [GO:0007411]; cellular response to leukemia inhibitory factor [GO:1990830]; cholesterol homeostasis [GO:0042632]; lipid catabolic process [GO:0016042]; lysophospholipid transport [GO:0051977]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of prostaglandin secretion [GO:0032308]; regulation of macrophage activation [GO:0043030]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipase activity [GO:0004620]
d1oqsf__d4qf8a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]
d1oqud__d1mrra___1			Actinobacteria	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1oqwb__d1oqvc___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]; cell adhesion [GO:0007155]	extracellular organelle [GO:0043230]; pilus [GO:0009289]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]	pathogenesis [GO:0009405]	pilus [GO:0009289]	extracellular organelle [GO:0043230]; pilus [GO:0009289]		
d1oqxa1_d4cnil1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]
d1oqxb2_d4wy7l1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	structural molecule activity [GO:0005198]
d1oqzb__d1pnm.1__1				Proteobacteria		periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]		antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]
d1or4a__d1uiwb___1		Metazoa	Firmicutes	Chordata	membrane [GO:0016020]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; aerotaxis [GO:0009454]; signal transduction [GO:0007165]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	aerotaxis [GO:0009454]; signal transduction [GO:0007165]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1or4a__d2uumv___1			Firmicutes	Cyanobacteria	membrane [GO:0016020]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; aerotaxis [GO:0009454]; signal transduction [GO:0007165]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	aerotaxis [GO:0009454]; signal transduction [GO:0007165]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	
d1or5a__d2faea___1			Actinobacteria	Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]		fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]
d1or6a__d1urya___1		Metazoa	Firmicutes	Chordata	membrane [GO:0016020]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; aerotaxis [GO:0009454]; signal transduction [GO:0007165]	cytosol [GO:0005829]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]; fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	aerotaxis [GO:0009454]; signal transduction [GO:0007165]	fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	membrane [GO:0016020]	cytosol [GO:0005829]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d1or6a__d2zfob___1		Metazoa	Firmicutes	Annelida	membrane [GO:0016020]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; aerotaxis [GO:0009454]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	aerotaxis [GO:0009454]; signal transduction [GO:0007165]		membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1or7a2_d2a6hf3__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]; DNA-templated transcription, initiation [GO:0006352]; regulation of transcription, DNA-templated [GO:0006355]; response to osmotic stress [GO:0006970]; response to temperature stimulus [GO:0009266]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	DNA-templated transcription, initiation [GO:0006352]; regulation of transcription, DNA-templated [GO:0006355]; response to osmotic stress [GO:0006970]; response to temperature stimulus [GO:0009266]	transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d1orba1_d1cwta___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5S rRNA binding [GO:0008097]; thiosulfate sulfurtransferase activity [GO:0004792]; rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; transsulfuration [GO:0019346]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; transsulfuration [GO:0019346]	cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	5S rRNA binding [GO:0008097]; thiosulfate sulfurtransferase activity [GO:0004792]	phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]
d1orfa__d1nfya___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; immunological synapse [GO:0001772]; nucleus [GO:0005634]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; immune response [GO:0006955]; negative regulation of DNA binding [GO:0043392]; negative regulation of endodeoxyribonuclease activity [GO:0032078]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to bacterium [GO:0009617]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; immune response [GO:0006955]; negative regulation of DNA binding [GO:0043392]; negative regulation of endodeoxyribonuclease activity [GO:0032078]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to bacterium [GO:0009617]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; immunological synapse [GO:0001772]; nucleus [GO:0005634]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1oria__d3kqya___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; [cytochrome c]-arginine N-methyltransferase activity [GO:0016275]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; histone-arginine N-methyltransferase activity [GO:0008469]; identical protein binding [GO:0042802]; methyl-CpG binding [GO:0008327]; protein methyltransferase activity [GO:0008276]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; snoRNP binding [GO:0030519]; histone H4-R3 methylation [GO:0043985]; liver regeneration [GO:0097421]; negative regulation of megakaryocyte differentiation [GO:0045653]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; peptidyl-arginine omega-N-methylation [GO:0035247]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hemoglobin biosynthetic process [GO:0046985]; positive regulation of p38MAPK cascade [GO:1900745]; protein homooligomerization [GO:0051260]; protein methylation [GO:0006479]; regulation of megakaryocyte differentiation [GO:0045652]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	histone H4-R3 methylation [GO:0043985]; liver regeneration [GO:0097421]; negative regulation of megakaryocyte differentiation [GO:0045653]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; peptidyl-arginine omega-N-methylation [GO:0035247]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hemoglobin biosynthetic process [GO:0046985]; positive regulation of p38MAPK cascade [GO:1900745]; protein homooligomerization [GO:0051260]; protein methylation [GO:0006479]; regulation of megakaryocyte differentiation [GO:0045652]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytosol [GO:0005829]; membrane [GO:0016020]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	[cytochrome c]-arginine N-methyltransferase activity [GO:0016275]; histone-arginine N-methyltransferase activity [GO:0008469]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; identical protein binding [GO:0042802]; methyl-CpG binding [GO:0008327]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; protein methyltransferase activity [GO:0008276]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; snoRNP binding [GO:0030519]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d1orja1_d3k1ib___1			Aquificae	Proteobacteria	bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]	cytosol [GO:0005829]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]	bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]	bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]		cytosol [GO:0005829]		
d1orjd1_d3iqcb___1			Aquificae	Proteobacteria	bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]	cytosol [GO:0005829]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]	bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]	bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]		cytosol [GO:0005829]		
d1orka1_d4j19b___1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	Cajal body [GO:0015030]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded telomeric DNA binding [GO:0003691]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; sequence-specific DNA binding [GO:0043565]; telomeric DNA binding [GO:0042162]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of chromatin binding [GO:0035563]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of telomerase activity [GO:0051972]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of chromatin binding [GO:0035563]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of telomerase activity [GO:0051972]		Cajal body [GO:0015030]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]	DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded telomeric DNA binding [GO:0003691]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; sequence-specific DNA binding [GO:0043565]; telomeric DNA binding [GO:0042162]
d1orna1_d3cwtd1__1				Proteobacteria		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1oroa__d4ohce___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; orotate phosphoribosyltransferase activity [GO:0004588]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine nucleotide biosynthetic process [GO:0006221]; pyrimidine ribonucleoside biosynthetic process [GO:0046132]	magnesium ion binding [GO:0000287]; orotate phosphoribosyltransferase activity [GO:0004588]; 'de novo' UMP biosynthetic process [GO:0044205]; nucleoside metabolic process [GO:0009116]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine nucleotide biosynthetic process [GO:0006221]; pyrimidine ribonucleoside biosynthetic process [GO:0046132]	'de novo' UMP biosynthetic process [GO:0044205]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		magnesium ion binding [GO:0000287]; orotate phosphoribosyltransferase activity [GO:0004588]	magnesium ion binding [GO:0000287]; orotate phosphoribosyltransferase activity [GO:0004588]
d1orqa2_d4z7wc2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	nutrient reservoir activity [GO:0045735]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	nutrient reservoir activity [GO:0045735]
d1orqb2_d1u8mb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1orqb2_d3x3gl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1orsa2_d2wubl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	proteolysis [GO:0006508]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1orsa2_d3agvb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1orsb1_d2wubq1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	proteolysis [GO:0006508]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1ortb2_d1a1sa1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1ortc1_d4wtoa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1ortd2_d1js1y1__1			Proteobacteria	Bacteroidetes	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]		amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]
d1orte2_d3e2pa2__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1ortf1_d2h3ea2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1ortf1_d3r7fb2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1ortg1_d2fg7e2__1			Proteobacteria	Bacteroidetes	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]		amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]
d1ortg1_d4iv5a1__1			Proteobacteria		cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; cellular amino acid metabolic process [GO:0006520]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]		amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1ortg2_d4a8ta2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; putrescine carbamoyltransferase activity [GO:0050231]; putrescine biosynthetic process from arginine via N-carbamoylputrescine [GO:0033390]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	putrescine biosynthetic process from arginine via N-carbamoylputrescine [GO:0033390]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; putrescine carbamoyltransferase activity [GO:0050231]
d1orth1_d3r7le1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1orth2_d4nf2c1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1ortk1_d1skua1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1ortk2_d1raia2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1ortl2_d4e2fk1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1orva2_d5jycc___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]		dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	hydrolase activity [GO:0016787]
d1orvc2_d2qjra2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1orvd2_d3kwja2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1orvd2_d4zwna1__1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; acylglycerol lipase activity [GO:0047372]; serine hydrolase activity [GO:0017171]; triglyceride catabolic process [GO:0019433]; triglyceride metabolic process [GO:0006641]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	triglyceride catabolic process [GO:0019433]; triglyceride metabolic process [GO:0006641]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	acylglycerol lipase activity [GO:0047372]; serine hydrolase activity [GO:0017171]
d1orwa2_d5iq2b___1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]		dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	hydrolase activity [GO:0016787]
d1orwb1_d5t4ba1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1orwb2_d3d2cj___1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	extracellular region [GO:0005576]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d1orwc2_d1lzla___1	Metazoa		Chordata	Actinobacteria	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]		dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	hydrolase activity [GO:0016787]
d1orwd2_d1to7b2__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]		dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	
d1os2a1_d1pwqb1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d1os2b1_d3o64b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d1os2c1_d1jkya2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d1os2d1_d1pe8a___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1os7d__d3v15d___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]; sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]	dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]	sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]		cytoplasm [GO:0005737]		L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]	dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]
d1os8a__d3sgqe___1		Metazoa	Actinobacteria	Chordata	serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]				extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1os9b1_d1j37a1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; sperm individualization [GO:0007291]; spermatid nucleus differentiation [GO:0007289]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; spermatid nucleus differentiation [GO:0007289]; sperm individualization [GO:0007291]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]
d1os9f1_d3leaa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d1osca__d1ufla___1	Metazoa		Chordata	Deinococcus-Thermus	membrane [GO:0016020]; copper ion binding [GO:0005507]; enzyme binding [GO:0019899]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; response to metal ion [GO:0010038]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]	protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; response to metal ion [GO:0010038]	regulation of nitrogen utilization [GO:0006808]	membrane [GO:0016020]		copper ion binding [GO:0005507]; enzyme binding [GO:0019899]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]
d1oscb__d4r25a1__1	Metazoa		Chordata	Firmicutes	membrane [GO:0016020]; copper ion binding [GO:0005507]; enzyme binding [GO:0019899]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; response to metal ion [GO:0010038]	plasma membrane [GO:0005886]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]	protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; response to metal ion [GO:0010038]	regulation of nitrogen utilization [GO:0006808]	membrane [GO:0016020]	plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; enzyme binding [GO:0019899]	enzyme regulator activity [GO:0030234]
d1oscc__d2v5hg___1	Metazoa		Chordata	Cyanobacteria	membrane [GO:0016020]; copper ion binding [GO:0005507]; enzyme binding [GO:0019899]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; response to metal ion [GO:0010038]	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; regulation of nitrogen utilization [GO:0006808]	protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; response to metal ion [GO:0010038]	regulation of nitrogen utilization [GO:0006808]	membrane [GO:0016020]		copper ion binding [GO:0005507]; enzyme binding [GO:0019899]	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d1osea1_d4lpcd3__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	extracellular space [GO:0005615]	cytosol [GO:0005829]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1osfa__d2brca___1	Metazoa	Fungi	Chordata	Ascomycota	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]
d1osfa__d3dgea2__1	Metazoa		Chordata	Thermotogae	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; protein autophosphorylation [GO:0046777]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	protein autophosphorylation [GO:0046777]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	integral component of plasma membrane [GO:0005887]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d1osia__d5yfmb___1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; 2-oxoglutarate metabolic process [GO:0006103]; female gonad development [GO:0008585]; glutathione metabolic process [GO:0006749]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; NADPH regeneration [GO:0006740]; neutrophil degranulation [GO:0043312]; protein targeting to peroxisome [GO:0006625]; regulation of phospholipid biosynthetic process [GO:0071071]; regulation of phospholipid catabolic process [GO:0060696]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	2-oxoglutarate metabolic process [GO:0006103]; female gonad development [GO:0008585]; glutathione metabolic process [GO:0006749]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADPH regeneration [GO:0006740]; NADP metabolic process [GO:0006739]; neutrophil degranulation [GO:0043312]; protein targeting to peroxisome [GO:0006625]; regulation of phospholipid biosynthetic process [GO:0071071]; regulation of phospholipid catabolic process [GO:0060696]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]
d1osid__d3ah3c___1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	homoisocitrate dehydrogenase activity [GO:0047046]; metal ion binding [GO:0046872]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	leucine biosynthetic process [GO:0009098]	lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]		3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	homoisocitrate dehydrogenase activity [GO:0047046]; metal ion binding [GO:0046872]
d1osph2_d3o2da2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1ospl2_d3g6je1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d1osza1_d1dn2a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1oszb__d4d9rl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ot1a1_d1v3ma1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1ot1a4_d5i78b1__1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cellulase activity [GO:0008810]
d1ot2a1_d1d7fb1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1ot2a1_d4gt0b2__1			Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1ot2a2_d1v3mb2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1ot2a4_d1jyyd5__1			Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	
d1ot3c__d2wwgc___1	Metazoa		Arthropoda	Apicomplexa	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]
d1ot4a__d2c9qa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]	copper ion binding [GO:0005507]
d1ot5b1_d2je8a4__1	Fungi		Ascomycota	Bacteroidetes	fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	beta-mannosidase activity [GO:0004567]
d1ot8b__d1ihbb___1	Metazoa	Metazoa	Arthropoda	Chordata	adherens junction [GO:0005912]; cell [GO:0005623]; cell surface [GO:0009986]; CSL-Notch-Mastermind transcription factor complex [GO:1990433]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; subapical complex [GO:0035003]; zonula adherens [GO:0005915]; calcium ion binding [GO:0005509]; chromatin binding [GO:0003682]; transmembrane signaling receptor activity [GO:0004888]; actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]; cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of phosphorylation [GO:0042326]; oligodendrocyte differentiation [GO:0048709]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; neuronal stem cell population maintenance [GO:0097150]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]	cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of phosphorylation [GO:0042326]; oligodendrocyte differentiation [GO:0048709]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	adherens junction [GO:0005912]; cell [GO:0005623]; cell surface [GO:0009986]; CSL-Notch-Mastermind transcription factor complex [GO:1990433]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; subapical complex [GO:0035003]; zonula adherens [GO:0005915]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; chromatin binding [GO:0003682]; transmembrane signaling receptor activity [GO:0004888]	cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]
d1ot8c__d3b95a1__1	Metazoa	Metazoa	Arthropoda	Chordata	adherens junction [GO:0005912]; cell [GO:0005623]; cell surface [GO:0009986]; CSL-Notch-Mastermind transcription factor complex [GO:1990433]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; subapical complex [GO:0035003]; zonula adherens [GO:0005915]; calcium ion binding [GO:0005509]; chromatin binding [GO:0003682]; transmembrane signaling receptor activity [GO:0004888]; actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; neuronal stem cell population maintenance [GO:0097150]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	adherens junction [GO:0005912]; cell [GO:0005623]; cell surface [GO:0009986]; CSL-Notch-Mastermind transcription factor complex [GO:1990433]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; subapical complex [GO:0035003]; zonula adherens [GO:0005915]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	calcium ion binding [GO:0005509]; chromatin binding [GO:0003682]; transmembrane signaling receptor activity [GO:0004888]	cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1otca1_d1xpra2__1			Ciliophora	Proteobacteria	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	telomere capping [GO:0016233]	DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	cytosol [GO:0005829]; membrane [GO:0016020]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]
d1otca3_d2qall1__1			Ciliophora		nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]		telomere capping [GO:0016233]		nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]		protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	
d1otda__d4gs9b___1		Metazoa	Proteobacteria	Chordata	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]		cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d1otdb__d5svga___1		Viridiplantae	Proteobacteria	Streptophyta	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; photoreceptor activity [GO:0009881]; circadian rhythm [GO:0007623]; flower development [GO:0009908]; protein ubiquitination [GO:0016567]; protein-chromophore linkage [GO:0018298]; response to blue light [GO:0009637]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	circadian rhythm [GO:0007623]; flower development [GO:0009908]; protein-chromophore linkage [GO:0018298]; protein ubiquitination [GO:0016567]; response to blue light [GO:0009637]		cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	photoreceptor activity [GO:0009881]
d1otea__d3s7na1__1			Proteobacteria	Deinococcus-Thermus	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d1otea__d4i38a___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d1otia__d2vv6b___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]		integral component of plasma membrane [GO:0005887]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d1otjb__d2y6fa___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]; sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]; penicillin biosynthetic process [GO:0042318]	sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]	penicillin biosynthetic process [GO:0042318]	cytoplasm [GO:0005737]		L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]
d1otjc__d5fyha___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]; sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cytoplasm [GO:0005737]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1otma__d5wk4b___1			Firmicutes		cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	
d1otoa__d1otma___1			Firmicutes	Firmicutes	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d1otpa1_d1gxbc1__1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; membrane [GO:0016020]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]	tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]
d1otsd2_d1g6ra1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1otse1_d2igfl2__1	Metazoa	Metazoa	Chordata	Annelida	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]
d1otsf1_d3pwje1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ottc1_d4isva1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ottc2_d5dfwh2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	basolateral plasma membrane [GO:0016323]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tetraspanin-enriched microdomain [GO:0097197]; vesicle [GO:0031982]; cholesterol binding [GO:0015485]; integrin binding [GO:0005178]; MHC class II protein binding [GO:0042289]; MHC class II protein complex binding [GO:0023026]; transferrin receptor binding [GO:1990459]; virus receptor activity [GO:0001618]; activation of MAPK activity [GO:0000187]; CD4-positive, alpha-beta T cell costimulation [GO:0035783]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunological synapse formation [GO:0001771]; macrophage fusion [GO:0034238]; myoblast fusion involved in skeletal muscle regeneration [GO:0014905]; osteoclast fusion [GO:0072675]; positive regulation of 1-phosphatidylinositol 4-kinase activity [GO:0043128]; positive regulation of adaptive immune memory response [GO:1905676]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein catabolic process in the vacuole [GO:1904352]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of receptor clustering [GO:1903911]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization [GO:0008104]; protein localization to lysosome [GO:0061462]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of macrophage migration [GO:1905521]; regulation of protein stability [GO:0031647]; viral entry into host cell [GO:0046718]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of MAPK activity [GO:0000187]; CD4-positive, alpha-beta T cell costimulation [GO:0035783]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunological synapse formation [GO:0001771]; macrophage fusion [GO:0034238]; myoblast fusion involved in skeletal muscle regeneration [GO:0014905]; osteoclast fusion [GO:0072675]; positive regulation of 1-phosphatidylinositol 4-kinase activity [GO:0043128]; positive regulation of adaptive immune memory response [GO:1905676]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein catabolic process in the vacuole [GO:1904352]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of receptor clustering [GO:1903911]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization [GO:0008104]; protein localization to lysosome [GO:0061462]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of macrophage migration [GO:1905521]; regulation of protein stability [GO:0031647]; viral entry into host cell [GO:0046718]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tetraspanin-enriched microdomain [GO:0097197]; vesicle [GO:0031982]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cholesterol binding [GO:0015485]; integrin binding [GO:0005178]; MHC class II protein binding [GO:0042289]; MHC class II protein complex binding [GO:0023026]; transferrin receptor binding [GO:1990459]; virus receptor activity [GO:0001618]
d1ottd2_d3mcll2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ottf2_d5f71b___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell junction [GO:0030054]; cell surface [GO:0009986]; early endosome [GO:0005769]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; mediator complex [GO:0016592]; metal ion binding [GO:0046872]; adaptive immune response [GO:0002250]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage activation involved in immune response [GO:0002281]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte colony-stimulating factor production [GO:0071656]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of interleukin-3 production [GO:0032712]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 1 type immune response [GO:0002826]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of chemokine production [GO:0032722]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of macrophage activation [GO:0043032]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of tolerance induction dependent upon immune response [GO:0002652]; regulation of transcription by RNA polymerase II [GO:0006357]; toll-like receptor 3 signaling pathway [GO:0034138]; toll-like receptor 7 signaling pathway [GO:0034154]; toll-like receptor 9 signaling pathway [GO:0034162]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage activation involved in immune response [GO:0002281]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte colony-stimulating factor production [GO:0071656]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of interleukin-3 production [GO:0032712]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 1 type immune response [GO:0002826]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of chemokine production [GO:0032722]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of macrophage activation [GO:0043032]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of tolerance induction dependent upon immune response [GO:0002652]; regulation of transcription by RNA polymerase II [GO:0006357]; toll-like receptor 3 signaling pathway [GO:0034138]; toll-like receptor 7 signaling pathway [GO:0034154]; toll-like receptor 9 signaling pathway [GO:0034162]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; cell surface [GO:0009986]; early endosome [GO:0005769]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; mediator complex [GO:0016592]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d1otuc2_d1cdia2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1otud1_d1jpsl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]
d1otud1_d5hy9b2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1otue1_d5ihzb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1otue2_d1qsfe2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1otue2_d3kj4b1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; presynapse [GO:0098793]; chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; Roundabout binding [GO:0048495]; signaling receptor activity [GO:0038023]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; presynapse [GO:0098793]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; Roundabout binding [GO:0048495]; signaling receptor activity [GO:0038023]
d1otuf1_d2illa2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1otuf1_d3qxva___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1otuf2_d1lmkg2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1otvb1_d4ny7a1__1			Proteobacteria	Proteobacteria	pyrroloquinoline-quinone synthase activity [GO:0033732]; pyrroloquinoline quinone biosynthetic process [GO:0018189]	pyrroloquinoline-quinone synthase activity [GO:0033732]; pyrroloquinoline quinone biosynthetic process [GO:0018189]	pyrroloquinoline quinone biosynthetic process [GO:0018189]	pyrroloquinoline quinone biosynthetic process [GO:0018189]			pyrroloquinoline-quinone synthase activity [GO:0033732]	pyrroloquinoline-quinone synthase activity [GO:0033732]
d1otxa__d3k8ot___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]
d1otyb__d3u40d1__1			Proteobacteria		cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]; membrane [GO:0016020]		identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d1ou4c__d5lhvf___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]
d1ou5a1_d1vfgb1__1	Metazoa		Chordata	Aquificae	intracellular [GO:0005622]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 5'-3' RNA polymerase activity [GO:0034062]; ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; tRNA binding [GO:0000049]; mitochondrial tRNA 3'-end processing [GO:1990180]; tRNA 3'-end processing [GO:0042780]; tRNA 3'-terminal CCA addition [GO:0001680]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleotidyltransferase activity [GO:0016779]; tRNA binding [GO:0000049]; tRNA processing [GO:0008033]	mitochondrial tRNA 3'-end processing [GO:1990180]; tRNA 3'-end processing [GO:0042780]; tRNA 3'-terminal CCA addition [GO:0001680]	tRNA processing [GO:0008033]	intracellular [GO:0005622]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]		5'-3' RNA polymerase activity [GO:0034062]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleotidyltransferase activity [GO:0016779]; tRNA binding [GO:0000049]
d1ou5b2_d3c5fa3__1	Metazoa	Metazoa	Chordata	Chordata	intracellular [GO:0005622]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 5'-3' RNA polymerase activity [GO:0034062]; ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; tRNA binding [GO:0000049]; mitochondrial tRNA 3'-end processing [GO:1990180]; tRNA 3'-end processing [GO:0042780]; tRNA 3'-terminal CCA addition [GO:0001680]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	mitochondrial tRNA 3'-end processing [GO:1990180]; tRNA 3'-end processing [GO:0042780]; tRNA 3'-terminal CCA addition [GO:0001680]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	intracellular [GO:0005622]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5'-3' RNA polymerase activity [GO:0034062]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; tRNA binding [GO:0000049]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d1ou6a2_d2gyoa2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1ou6b2_d2ebda1__1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1ouba__d3sb6b1__1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ouca__d4i7lb1__1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ouda__d2hsoa1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1oufa__d1pqka___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ouha__d2dbta___1	Metazoa		Chordata	Actinobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]
d1ouia__d1jtna___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ouja__d4dwxb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]; polysaccharide catabolic process [GO:0000272]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]; polysaccharide catabolic process [GO:0000272]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d1ouka__d4rixd___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; spindle pole [GO:0000922]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; MAP kinase activity [GO:0004707]; MAP kinase kinase activity [GO:0004708]; mitogen-activated protein kinase p38 binding [GO:0048273]; NFAT protein binding [GO:0051525]; protein phosphatase binding [GO:0019903]; protein serine/threonine kinase activity [GO:0004674]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cartilage condensation [GO:0001502]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; cellular response to ionizing radiation [GO:0071479]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; chondrocyte differentiation [GO:0002062]; DNA damage checkpoint [GO:0000077]; fatty acid oxidation [GO:0019395]; glucose metabolic process [GO:0006006]; intracellular signal transduction [GO:0035556]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neutrophil degranulation [GO:0043312]; osteoclast differentiation [GO:0030316]; p38MAPK cascade [GO:0038066]; peptidyl-serine phosphorylation [GO:0018105]; placenta development [GO:0001890]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cyclase activity [GO:0031281]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Ras protein signal transduction [GO:0007265]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of gene expression [GO:0010468]; regulation of ossification [GO:0030278]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of synaptic membrane adhesion [GO:0099179]; regulation of transcription by RNA polymerase II [GO:0006357]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; signal transduction in response to DNA damage [GO:0042770]; skeletal muscle tissue development [GO:0007519]; stress-induced premature senescence [GO:0090400]; striated muscle cell differentiation [GO:0051146]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	3'-UTR-mediated mRNA stabilization [GO:0070935]; activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cartilage condensation [GO:0001502]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; cellular response to ionizing radiation [GO:0071479]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; chondrocyte differentiation [GO:0002062]; DNA damage checkpoint [GO:0000077]; fatty acid oxidation [GO:0019395]; glucose metabolic process [GO:0006006]; intracellular signal transduction [GO:0035556]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neutrophil degranulation [GO:0043312]; osteoclast differentiation [GO:0030316]; p38MAPK cascade [GO:0038066]; peptidyl-serine phosphorylation [GO:0018105]; placenta development [GO:0001890]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cyclase activity [GO:0031281]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Ras protein signal transduction [GO:0007265]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of gene expression [GO:0010468]; regulation of ossification [GO:0030278]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of synaptic membrane adhesion [GO:0099179]; regulation of transcription by RNA polymerase II [GO:0006357]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; signal transduction in response to DNA damage [GO:0042770]; skeletal muscle tissue development [GO:0007519]; stress-induced premature senescence [GO:0090400]; striated muscle cell differentiation [GO:0051146]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; spindle pole [GO:0000922]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	ATP binding [GO:0005524]; enzyme binding [GO:0019899]; MAP kinase activity [GO:0004707]; MAP kinase kinase activity [GO:0004708]; mitogen-activated protein kinase p38 binding [GO:0048273]; NFAT protein binding [GO:0051525]; protein phosphatase binding [GO:0019903]; protein serine/threonine kinase activity [GO:0004674]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d1ounb__d2xr8t___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]		identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1outa__d1gh0u___1	Metazoa		Chordata	Cyanobacteria	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1outa__d2ri4j___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1outb__d1a9we___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1outb__d5aqdh___1	Metazoa		Chordata	Cyanobacteria	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1ouua__d4lmxj___1	Metazoa		Chordata	Cryptophyta	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	chloroplast [GO:0009507]; phycobilisome [GO:0030089]; protein-chromophore linkage [GO:0018298]		protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	chloroplast [GO:0009507]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1ouub__d5v3va___1	Metazoa		Chordata	Firmicutes	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen transport [GO:0015671]		oxygen transport [GO:0015671]	hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d1ouuc__d5kkka___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ouzb__d5lvtc___1			Proteobacteria	Firmicutes	chromosome [GO:0005694]; cytosol [GO:0005829]; DNA binding [GO:0003677]; conjugation [GO:0000746]; DNA recombination [GO:0006310]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]	conjugation [GO:0000746]; DNA recombination [GO:0006310]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]	chromosome condensation [GO:0030261]	chromosome [GO:0005694]; cytosol [GO:0005829]		DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1ov6a__d3nm5a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	cytosol [GO:0005829]; membrane [GO:0016020]		identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d1ov7a__d2iffy___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ov8b__d2hrha3__1		Fungi	Chloroflexi	Basidiomycota	plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; oxidation-reduction process [GO:0055114]; photosynthetic electron transport chain [GO:0009767]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	oxidation-reduction process [GO:0055114]; photosynthetic electron transport chain [GO:0009767]		plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1ov8c__d2pp9c2__1			Chloroflexi	Proteobacteria	plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; oxidation-reduction process [GO:0055114]; photosynthetic electron transport chain [GO:0009767]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]; photosynthetic electron transport chain [GO:0009767]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1ov8d__d1gs6x1__1			Chloroflexi	Proteobacteria	plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; oxidation-reduction process [GO:0055114]; photosynthetic electron transport chain [GO:0009767]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]; photosynthetic electron transport chain [GO:0009767]	nitrogen compound metabolic process [GO:0006807]	plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1ov8d__d2ft8a___1			Chloroflexi	Proteobacteria	plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; oxidation-reduction process [GO:0055114]; photosynthetic electron transport chain [GO:0009767]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]; photosynthetic electron transport chain [GO:0009767]	oxidation-reduction process [GO:0055114]	plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1ovba__d4p0ia___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	nitrogen compound transport [GO:0071705]	extracellular space [GO:0005615]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]	ligand-gated ion channel activity [GO:0015276]
d1ovba__d5hbcb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	extracellular space [GO:0005615]	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]	metal ion binding [GO:0046872]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d1ovga__d2qsub___1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d1ovgb__d3phcc___1			Proteobacteria	Apicomplexa	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]; membrane [GO:0016020]		identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d1ovgc__d5epue___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]
d1ovja__d4hp0a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ovmb1_d4jucc2__1			Proteobacteria	Proteobacteria	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; auxin biosynthetic process [GO:0009851]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	auxin biosynthetic process [GO:0009851]	mandelate catabolic process [GO:0019596]			indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1ovmc3_d4k9la3__1			Proteobacteria	Proteobacteria	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; auxin biosynthetic process [GO:0009851]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	auxin biosynthetic process [GO:0009851]	mandelate catabolic process [GO:0019596]			indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1ovmd1_d1jsca1__1		Fungi	Proteobacteria	Ascomycota	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; auxin biosynthetic process [GO:0009851]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	auxin biosynthetic process [GO:0009851]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1ovmd2_d1t9aa2__1		Fungi	Proteobacteria	Ascomycota	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; auxin biosynthetic process [GO:0009851]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	auxin biosynthetic process [GO:0009851]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1ovmd3_d3exhf1__1		Metazoa	Proteobacteria	Chordata	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; auxin biosynthetic process [GO:0009851]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	auxin biosynthetic process [GO:0009851]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1ovnb2_d2c1ya2__1	Metazoa	Metazoa	Arthropoda	Arthropoda	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; protein homodimerization activity [GO:0042803]; dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; protein homodimerization activity [GO:0042803]; dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	protein homodimerization activity [GO:0042803]	protein homodimerization activity [GO:0042803]
d1ovsc__d2vnvc___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1ovsc__d5mb1a___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1ovwa__d1dyma___1	Fungi	Fungi	Ascomycota	Ascomycota	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	cellulase activity [GO:0008810]	cellulase activity [GO:0008810]
d1ovwb__d1vala___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cellulose catabolic process [GO:0030245]				cellulase activity [GO:0008810]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1ovzb1_d1e6oh2__1	Metazoa		Chordata		extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]	
d1ow0a2_d3durd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]	
d1ow0b2_d1rivh2__1	Metazoa		Chordata		extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]	
d1ow0b2_d4o5ll1__1	Metazoa		Chordata		extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]	
d1ow6a__d3gm3a___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	apical dendrite [GO:0097440]; cell [GO:0005623]; cell body [GO:0044297]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase binding [GO:0043423]; ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; NMDA glutamate receptor activity [GO:0004972]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein C-terminus binding [GO:0008022]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; ubiquitin protein ligase binding [GO:0031625]; activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-containing complex assembly [GO:0065003]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of NMDA receptor activity [GO:2000310]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of synaptic plasticity [GO:0048167]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; protein-containing complex assembly [GO:0065003]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of NMDA receptor activity [GO:2000310]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of synaptic plasticity [GO:0048167]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]	apical dendrite [GO:0097440]; cell [GO:0005623]; cell body [GO:0044297]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]	actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]	3-phosphoinositide-dependent protein kinase binding [GO:0043423]; ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; NMDA glutamate receptor activity [GO:0004972]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein tyrosine kinase activity [GO:0004713]; ubiquitin protein ligase binding [GO:0031625]
d1ow6c__d3gm1b___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	apical dendrite [GO:0097440]; cell [GO:0005623]; cell body [GO:0044297]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase binding [GO:0043423]; ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; NMDA glutamate receptor activity [GO:0004972]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein C-terminus binding [GO:0008022]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; ubiquitin protein ligase binding [GO:0031625]; activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-containing complex assembly [GO:0065003]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of NMDA receptor activity [GO:2000310]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of synaptic plasticity [GO:0048167]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; protein-containing complex assembly [GO:0065003]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of NMDA receptor activity [GO:2000310]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of synaptic plasticity [GO:0048167]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]	apical dendrite [GO:0097440]; cell [GO:0005623]; cell body [GO:0044297]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]	actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]	3-phosphoinositide-dependent protein kinase binding [GO:0043423]; ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; NMDA glutamate receptor activity [GO:0004972]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein tyrosine kinase activity [GO:0004713]; ubiquitin protein ligase binding [GO:0031625]
d1owda__d2qcya___1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1owea__d3rxqa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	digestion [GO:0007586]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1owga__d2ndpb___1			Proteobacteria	Tenericutes	chromosome [GO:0005694]; cytosol [GO:0005829]; DNA binding [GO:0003677]; conjugation [GO:0000746]; DNA recombination [GO:0006310]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]	conjugation [GO:0000746]; DNA recombination [GO:0006310]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]		chromosome [GO:0005694]; cytosol [GO:0005829]		DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1owia__d1iqja___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1owja__d5c20a1__1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1owla1_d1np7b1__1			Cyanobacteria	Cyanobacteria	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	DNA binding [GO:0003677]; DNA photolyase activity [GO:0003913]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]			deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA photolyase activity [GO:0003913]
d1owla2_d2wq6a1__1		Metazoa	Cyanobacteria	Arthropoda	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	nucleotide binding [GO:0000166]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]				deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d1owoa1_d3cvva2__1		Metazoa	Cyanobacteria	Arthropoda	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	nucleotide binding [GO:0000166]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]				deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d1owoa2_d4i6ga1__1		Metazoa	Cyanobacteria	Chordata	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; FAD binding [GO:0071949]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; phosphatase binding [GO:0019902]; photoreceptor activity [GO:0009881]; protein kinase binding [GO:0019901]; single-stranded DNA binding [GO:0003697]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; protein import into nucleus [GO:0006606]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-chromophore linkage [GO:0018298]; protein import into nucleus [GO:0006606]; regulation of circadian rhythm [GO:0042752]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; FAD binding [GO:0071949]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; phosphatase binding [GO:0019902]; photoreceptor activity [GO:0009881]; protein kinase binding [GO:0019901]; single-stranded DNA binding [GO:0003697]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1owpa2_d1dnpb2__1			Cyanobacteria	Proteobacteria	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]			deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]
d1owpa2_d2wq7a1__1		Metazoa	Cyanobacteria	Arthropoda	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	nucleotide binding [GO:0000166]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]				deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d1owrm2_d2xwrb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1owrp1_d1wcqb1__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	metabolic process [GO:0008152]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	extracellular region [GO:0005576]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1owrp2_d2mejb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1owrq2_d1le5f2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1owrq2_d2wgxa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1owza__d2dqjy___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ox0a1_d4wyrb2__1			Firmicutes	Firmicutes	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]	fatty acid biosynthetic process [GO:0006633]			cytoplasm [GO:0005737]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1ox6a2_d1gg9c1__1	Fungi		Ascomycota	Proteobacteria	intracellular [GO:0005622]; glutaminase activity [GO:0004359]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; oxo-acid-lyase activity [GO:0016833]; glutamine metabolic process [GO:0006541]; histidine biosynthetic process [GO:0000105]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	glutamine metabolic process [GO:0006541]; histidine biosynthetic process [GO:0000105]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	intracellular [GO:0005622]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutaminase activity [GO:0004359]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; oxo-acid-lyase activity [GO:0016833]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1ox9f__d2qazd___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; ribosome [GO:0005840]; ATPase binding [GO:0051117]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; positive regulation of ATPase activity [GO:0032781]; positive regulation of protein catabolic process [GO:0045732]	identical protein binding [GO:0042802]	positive regulation of ATPase activity [GO:0032781]; positive regulation of protein catabolic process [GO:0045732]		cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; ribosome [GO:0005840]		ATPase binding [GO:0051117]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]	identical protein binding [GO:0042802]
d1oxcd__d5a6yc___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1oxhd1_d1m1tb2__1			Firmicutes	Proteobacteria	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1oxkb__d1ffsc___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]; osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]	histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d1oxkb__d3w9sb___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; nucleus [GO:0005634]; histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]; osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]		osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]; nucleus [GO:0005634]		histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]	
d1oxkd__d2jk1a___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]; osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]	ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d1oxkl__d4hnra___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]; osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	phosphorelay signal transduction system [GO:0000160]	osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]	
d1oxma__d5t4ta1__1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	haloacetate dehalogenase activity [GO:0018785]			extracellular region [GO:0005576]		cutinase activity [GO:0050525]	haloacetate dehalogenase activity [GO:0018785]
d1oxmb__d3wqha2__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cutinase activity [GO:0050525]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1oxob__d4tmra___1	Metazoa		Chordata	Apicomplexa	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d1oxpa__d1gc3c___1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	cytoplasm [GO:0005737]; aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	biosynthetic process [GO:0009058]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]	aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]
d1oxpa__d1gtxd___1	Metazoa		Chordata		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]		2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]	
d1oxra__d1jlta___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; host cell postsynaptic membrane [GO:0035792]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; hemolysis in other organism [GO:0044179]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; hemolysis in other organism [GO:0044179]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell postsynaptic membrane [GO:0035792]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1oxub1_d1h9ja2__1			Crenarchaeota	Proteobacteria	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; carbohydrate transport [GO:0008643]	molybdate ion transport [GO:0015689]	carbohydrate transport [GO:0008643]	molybdate ion transport [GO:0015689]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]	
d1oxub2_d2ia5a2__1			Crenarchaeota		ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; carbohydrate transport [GO:0008643]	ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; deoxynucleotide 3'-phosphatase activity [GO:0047846]; DNA repair [GO:0006281]; viral process [GO:0016032]	carbohydrate transport [GO:0008643]	DNA repair [GO:0006281]; viral process [GO:0016032]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]	ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; deoxynucleotide 3'-phosphatase activity [GO:0047846]
d1oxuc1_d1guna___1			Crenarchaeota	Firmicutes	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; carbohydrate transport [GO:0008643]	molybdate ion transport [GO:0015689]	carbohydrate transport [GO:0008643]	molybdate ion transport [GO:0015689]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]	
d1oxuc2_d1e1rb3__1		Metazoa	Crenarchaeota	Chordata	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; carbohydrate transport [GO:0008643]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	carbohydrate transport [GO:0008643]	ATP synthesis coupled proton transport [GO:0015986]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1oxva1_d1guob___1			Crenarchaeota	Firmicutes	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; carbohydrate transport [GO:0008643]	molybdate ion transport [GO:0015689]	carbohydrate transport [GO:0008643]	molybdate ion transport [GO:0015689]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]	
d1oxvb1_d3pv0a2__1			Crenarchaeota	Proteobacteria	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; carbohydrate transport [GO:0008643]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	carbohydrate transport [GO:0008643]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1oxvb2_d2hldv2__1		Fungi	Crenarchaeota	Ascomycota	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; carbohydrate transport [GO:0008643]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	carbohydrate transport [GO:0008643]	ATP synthesis coupled proton transport [GO:0015986]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1oxvd2_d2j0ua1__1		Metazoa	Crenarchaeota	Chordata	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; carbohydrate transport [GO:0008643]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; U2-type catalytic step 1 spliceosome [GO:0071006]; ATP binding [GO:0005524]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA stem-loop binding [GO:0035613]; selenocysteine insertion sequence binding [GO:0035368]; translation regulator activity [GO:0045182]; associative learning [GO:0008306]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to selenite ion [GO:0072715]; embryonic cranial skeleton morphogenesis [GO:0048701]; exploration behavior [GO:0035640]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of selenocysteine incorporation [GO:1904570]; negative regulation of selenocysteine insertion sequence binding [GO:1904574]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; response to organic cyclic compound [GO:0014070]; RNA export from nucleus [GO:0006405]; rRNA processing [GO:0006364]	carbohydrate transport [GO:0008643]	associative learning [GO:0008306]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to selenite ion [GO:0072715]; embryonic cranial skeleton morphogenesis [GO:0048701]; exploration behavior [GO:0035640]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of selenocysteine incorporation [GO:1904570]; negative regulation of selenocysteine insertion sequence binding [GO:1904574]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; response to organic cyclic compound [GO:0014070]; RNA export from nucleus [GO:0006405]; rRNA processing [GO:0006364]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; U2-type catalytic step 1 spliceosome [GO:0071006]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]	ATP binding [GO:0005524]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA stem-loop binding [GO:0035613]; selenocysteine insertion sequence binding [GO:0035368]; translation regulator activity [GO:0045182]
d1oxxk1_d1gunb___1			Crenarchaeota	Firmicutes	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; carbohydrate transport [GO:0008643]	molybdate ion transport [GO:0015689]	carbohydrate transport [GO:0008643]	molybdate ion transport [GO:0015689]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]	
d1oy3b__d3edja1__1	Metazoa		Chordata	Bacteroidetes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; cellular response to lipopolysaccharide [GO:0071222]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; signal transduction [GO:0007165]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cellular response to lipopolysaccharide [GO:0071222]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; signal transduction [GO:0007165]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]			cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d1oy9a1_d2dhha6__1			Proteobacteria	Proteobacteria	efflux pump complex [GO:1990281]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; efflux transmembrane transporter activity [GO:0015562]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]; drug transmembrane transport [GO:0006855]; response to drug [GO:0042493]	efflux pump complex [GO:1990281]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; efflux transmembrane transporter activity [GO:0015562]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]; drug transmembrane transport [GO:0006855]; response to drug [GO:0042493]	drug transmembrane transport [GO:0006855]; response to drug [GO:0042493]	drug transmembrane transport [GO:0006855]; response to drug [GO:0042493]	efflux pump complex [GO:1990281]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	efflux pump complex [GO:1990281]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	efflux transmembrane transporter activity [GO:0015562]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]	efflux transmembrane transporter activity [GO:0015562]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]
d1oyaa__d5cpoa___1	Fungi		Ascomycota	Proteobacteria	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d1oyea1_d2dhhb6__1			Proteobacteria	Proteobacteria	efflux pump complex [GO:1990281]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; efflux transmembrane transporter activity [GO:0015562]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]; drug transmembrane transport [GO:0006855]; response to drug [GO:0042493]	efflux pump complex [GO:1990281]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; efflux transmembrane transporter activity [GO:0015562]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]; drug transmembrane transport [GO:0006855]; response to drug [GO:0042493]	drug transmembrane transport [GO:0006855]; response to drug [GO:0042493]	drug transmembrane transport [GO:0006855]; response to drug [GO:0042493]	efflux pump complex [GO:1990281]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	efflux pump complex [GO:1990281]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	efflux transmembrane transporter activity [GO:0015562]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]	efflux transmembrane transporter activity [GO:0015562]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]
d1oyga__d1uypf2__1			Firmicutes	Thermotogae	extracellular region [GO:0005576]; levansucrase activity [GO:0050053]; carbohydrate utilization [GO:0009758]	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	carbohydrate utilization [GO:0009758]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		levansucrase activity [GO:0050053]	beta-fructofuranosidase activity [GO:0004564]
d1oyjb2_d4k1fb___1	Viridiplantae		Streptophyta		cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	cell [GO:0005623]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	glutathione transferase activity [GO:0004364]	peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]
d1oyla__d2gm7b2__1	Metazoa		Chordata	Crenarchaeota	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cytosol [GO:0005829]; thiaminase activity [GO:0050334]; thiamine metabolic process [GO:0006772]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	thiamine metabolic process [GO:0006772]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cytosol [GO:0005829]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	thiaminase activity [GO:0050334]
d1oyla__d4wd4d___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1oymb__d2weyb1__1		Metazoa		Chordata		cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]		cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]		cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]		3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d1oyna__d3ituc___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d1oync__d3uuob___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d1oypb2_d3b4tf2__1			Firmicutes	Actinobacteria	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	plasma membrane [GO:0005886]; 3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]		plasma membrane [GO:0005886]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d1oypc2_d2wnrc2__1			Firmicutes	Euryarchaeota	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	RNA catabolic process [GO:0006401]		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	3'-5'-exoribonuclease activity [GO:0000175]
d1oypd2_d2c39g2__1			Firmicutes	Crenarchaeota	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	3'-5'-exoribonuclease activity [GO:0000175]
d1oype2_d3b4td2__1			Firmicutes	Actinobacteria	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	plasma membrane [GO:0005886]; 3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]		plasma membrane [GO:0005886]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d1oypf2_d3l7zg2__1			Firmicutes	Crenarchaeota	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d1oyrc1_d2ba1e1__1			Firmicutes	Euryarchaeota	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1oyrd1_d1n32i___1			Firmicutes	Deinococcus-Thermus	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	translation [GO:0006412]		ribosome [GO:0005840]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1oyrf2_d2c37e2__1			Firmicutes	Crenarchaeota	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	3'-5'-exoribonuclease activity [GO:0000175]
d1oysa2_d2c38o2__1			Firmicutes	Crenarchaeota	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	3'-5'-exoribonuclease activity [GO:0000175]
d1oyua__d1lz4a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1oyua__d5jwua___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1oyub__d1t8aa___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1oyub__d4n1ei___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1oyvb__d1y9zb___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1oyya1_d3ikva1__1			Proteobacteria	Deinococcus-Thermus	bacterial nucleoid [GO:0043590]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; replisome [GO:0030894]; single-stranded DNA-dependent ATP-dependent DNA helicase complex [GO:0017117]; 3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA-dependent ATPase activity [GO:0008094]; four-way junction helicase activity [GO:0009378]; single-stranded DNA helicase activity [GO:0017116]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432]	cytoplasm [GO:0005737]; coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]	cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432]	negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]	bacterial nucleoid [GO:0043590]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; replisome [GO:0030894]; single-stranded DNA-dependent ATP-dependent DNA helicase complex [GO:0017117]	cytoplasm [GO:0005737]	3'-5' DNA helicase activity [GO:0043138]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA helicase activity [GO:0003678]; four-way junction helicase activity [GO:0009378]; single-stranded DNA helicase activity [GO:0017116]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1oyya2_d1foed___1		Metazoa	Proteobacteria	Chordata	bacterial nucleoid [GO:0043590]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; replisome [GO:0030894]; single-stranded DNA-dependent ATP-dependent DNA helicase complex [GO:0017117]; 3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA-dependent ATPase activity [GO:0008094]; four-way junction helicase activity [GO:0009378]; single-stranded DNA helicase activity [GO:0017116]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; histone deacetylase binding [GO:0042826]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cell-matrix adhesion [GO:0007160]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	bacterial nucleoid [GO:0043590]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; replisome [GO:0030894]; single-stranded DNA-dependent ATP-dependent DNA helicase complex [GO:0017117]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]	3'-5' DNA helicase activity [GO:0043138]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA helicase activity [GO:0003678]; four-way junction helicase activity [GO:0009378]; single-stranded DNA helicase activity [GO:0017116]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; histone deacetylase binding [GO:0042826]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]
d1oz0a2_d3ocqa___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	'de novo' IMP biosynthetic process [GO:0006189]	tRNA wobble adenosine to inosine editing [GO:0002100]	cytosol [GO:0005829]		IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]
d1oz2a1_d2rjcc2__1	Metazoa	Metazoa	Chordata	Chordata	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]; chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]; chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]
d1oz7a__d1g1rd1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]		calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]	toxin activity [GO:0090729]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]
d1oz7a__d2ox9d___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; low-density lipoprotein particle binding [GO:0030169]; metal ion binding [GO:0046872]; signaling pattern recognition receptor activity [GO:0008329]; transmembrane signaling receptor activity [GO:0004888]; cellular response to exogenous dsRNA [GO:0071360]; immune response [GO:0006955]; phagocytosis, recognition [GO:0006910]; positive regulation of cell adhesion molecule production [GO:0060355]; toll-like receptor 3 signaling pathway [GO:0034138]		cellular response to exogenous dsRNA [GO:0071360]; immune response [GO:0006955]; phagocytosis, recognition [GO:0006910]; positive regulation of cell adhesion molecule production [GO:0060355]; toll-like receptor 3 signaling pathway [GO:0034138]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; integral component of membrane [GO:0016021]	toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; low-density lipoprotein particle binding [GO:0030169]; metal ion binding [GO:0046872]; signaling pattern recognition receptor activity [GO:0008329]; transmembrane signaling receptor activity [GO:0004888]
d1ozba__d5jtrb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cytoplasm [GO:0005737]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	unfolded protein binding [GO:0051082]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1ozbb__d5jtoc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	unfolded protein binding [GO:0051082]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1ozbc__d5jtnc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	unfolded protein binding [GO:0051082]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1ozbf__d5jtoa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	unfolded protein binding [GO:0051082]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1ozbh__d5jtla___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	protein folding [GO:0006457]; protein tetramerization [GO:0051262]; protein transport [GO:0015031]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	unfolded protein binding [GO:0051082]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1ozea__d1ni6a___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1ozeb__d5uc9c___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d1ozgb3_d1ovmb3__1			Proteobacteria	Proteobacteria	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; butanediol metabolic process [GO:0034077]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; auxin biosynthetic process [GO:0009851]	butanediol metabolic process [GO:0034077]	auxin biosynthetic process [GO:0009851]			acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1ozgb3_d2wvhf3__1			Proteobacteria	Proteobacteria	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; butanediol metabolic process [GO:0034077]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	butanediol metabolic process [GO:0034077]				acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1ozha3_d2wvga3__1			Proteobacteria	Proteobacteria	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; butanediol metabolic process [GO:0034077]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	butanediol metabolic process [GO:0034077]				acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1ozia__d4k76b___1	Metazoa	Metazoa	Chordata	Chordata	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; midbody [GO:0030496]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; midbody [GO:0030496]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]	ion channel binding [GO:0044325]
d1ozlb__d2qppb___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d1ozoa__d1eg4a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; microvillus membrane [GO:0031528]; nuclear body [GO:0016604]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; transition metal ion binding [GO:0046914]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; response to organic substance [GO:0010033]	basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; contractile ring [GO:0070938]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystroglycan complex [GO:0016011]; dystrophin-associated glycoprotein complex [GO:0016010]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; node of Ranvier [GO:0033268]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]; actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; calcium ion binding [GO:0005509]; dystroglycan binding [GO:0002162]; laminin-1 binding [GO:0043237]; SH2 domain binding [GO:0042169]; structural constituent of muscle [GO:0008307]; tubulin binding [GO:0015631]; vinculin binding [GO:0017166]; virus receptor activity [GO:0001618]; aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; extracellular matrix organization [GO:0030198]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of embryonic cell shape [GO:0016476]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; skeletal muscle tissue regeneration [GO:0043403]	endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; response to organic substance [GO:0010033]	aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; extracellular matrix organization [GO:0030198]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of embryonic cell shape [GO:0016476]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; skeletal muscle tissue regeneration [GO:0043403]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; microvillus membrane [GO:0031528]; nuclear body [GO:0016604]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; contractile ring [GO:0070938]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystroglycan complex [GO:0016011]; dystrophin-associated glycoprotein complex [GO:0016010]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; node of Ranvier [GO:0033268]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]	cadherin binding [GO:0045296]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; transition metal ion binding [GO:0046914]	actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; calcium ion binding [GO:0005509]; dystroglycan binding [GO:0002162]; laminin-1 binding [GO:0043237]; SH2 domain binding [GO:0042169]; structural constituent of muscle [GO:0008307]; tubulin binding [GO:0015631]; vinculin binding [GO:0017166]; virus receptor activity [GO:0001618]
d1p0ca2_d1he2a___1	Metazoa	Metazoa	Chordata	Chordata	alcohol dehydrogenase (NADP+) activity [GO:0008106]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; terminal bouton [GO:0043195]; biliverdin reductase activity [GO:0004074]; riboflavin reductase (NADPH) activity [GO:0042602]; heme catabolic process [GO:0042167]		heme catabolic process [GO:0042167]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; terminal bouton [GO:0043195]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; zinc ion binding [GO:0008270]	biliverdin reductase activity [GO:0004074]; riboflavin reductase (NADPH) activity [GO:0042602]
d1p0fa2_d1ntob2__1	Metazoa		Chordata	Crenarchaeota	alcohol dehydrogenase (NADP+) activity [GO:0008106]; zinc ion binding [GO:0008270]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]					alcohol dehydrogenase (NADP+) activity [GO:0008106]; zinc ion binding [GO:0008270]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]
d1p0fa2_d5in5d1__1	Metazoa	Metazoa	Chordata	Chordata	alcohol dehydrogenase (NADP+) activity [GO:0008106]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GDP-mannose 4,6-dehydratase activity [GO:0008446]; identical protein binding [GO:0042802]; NADP+ binding [GO:0070401]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; Notch signaling pathway [GO:0007219]		'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; Notch signaling pathway [GO:0007219]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; zinc ion binding [GO:0008270]	GDP-mannose 4,6-dehydratase activity [GO:0008446]; identical protein binding [GO:0042802]; NADP+ binding [GO:0070401]
d1p0fb2_d4bmsf___1	Metazoa		Chordata	Proteobacteria	alcohol dehydrogenase (NADP+) activity [GO:0008106]; zinc ion binding [GO:0008270]	nucleotide binding [GO:0000166]					alcohol dehydrogenase (NADP+) activity [GO:0008106]; zinc ion binding [GO:0008270]	nucleotide binding [GO:0000166]
d1p0za1_d3by8a___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; phosphorelay signal transduction system [GO:0000160]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction by protein phosphorylation [GO:0023014]		phosphorelay signal transduction system [GO:0000160]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction by protein phosphorylation [GO:0023014]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d1p0zc1_d3libe___1			Proteobacteria	Euryarchaeota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]	integral component of membrane [GO:0016021]; kinase activity [GO:0016301]; signal transduction [GO:0007165]		signal transduction [GO:0007165]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]	kinase activity [GO:0016301]
d1p0zd1_d3lidb2__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]				integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]	
d1p0zf1_d5avea1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]	integral component of membrane [GO:0016021]; signal transduction [GO:0007165]		signal transduction [GO:0007165]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]	
d1p12e__d2bdig___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]		amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1p13b__d2mk2a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; connexin binding [GO:0071253]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; osteoclast development [GO:0036035]; peptidyl-tyrosine autophosphorylation [GO:0038083]; progesterone receptor signaling pathway [GO:0050847]; regulation of cell population proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; hydrolase activity [GO:0016787]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cytokine-mediated signaling pathway [GO:0019221]; endochondral ossification [GO:0001958]; endocytosis [GO:0006897]; glucose metabolic process [GO:0006006]; immune system process [GO:0002376]; inositol phosphate metabolic process [GO:0043647]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; post-embryonic development [GO:0009791]; response to insulin [GO:0032868]; ruffle assembly [GO:0097178]	bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; osteoclast development [GO:0036035]; peptidyl-tyrosine autophosphorylation [GO:0038083]; progesterone receptor signaling pathway [GO:0050847]; regulation of cell population proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cytokine-mediated signaling pathway [GO:0019221]; endochondral ossification [GO:0001958]; endocytosis [GO:0006897]; glucose metabolic process [GO:0006006]; immune system process [GO:0002376]; inositol phosphate metabolic process [GO:0043647]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; post-embryonic development [GO:0009791]; response to insulin [GO:0032868]; ruffle assembly [GO:0097178]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; lamellipodium [GO:0030027]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; connexin binding [GO:0071253]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]	actin binding [GO:0003779]; hydrolase activity [GO:0016787]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]
d1p1bb__d3ubtb___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]	DNA restriction-modification system [GO:0009307]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d1p1ea__d4joja___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; glucocorticoid receptor binding [GO:0035259]; receptor signaling complex adaptor activity [GO:0030159]; signaling receptor binding [GO:0005102]; dendrite development [GO:0016358]; nervous system development [GO:0007399]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection arborization [GO:0150012]; protein transport [GO:0015031]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	dendrite development [GO:0016358]; nervous system development [GO:0007399]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection arborization [GO:0150012]; protein transport [GO:0015031]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	glucocorticoid receptor binding [GO:0035259]; receptor signaling complex adaptor activity [GO:0030159]; signaling receptor binding [GO:0005102]	ion channel binding [GO:0044325]
d1p1ga__d2wkfa___1	Metazoa		Chordata	Apicomplexa	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cytoplasm [GO:0005737]; host cell cytoplasm [GO:0030430]; Maurer's cleft [GO:0020036]; cytokine activity [GO:0005125]; host cell surface receptor binding [GO:0046789]; oxidoreductase activity [GO:0016491]; phenylpyruvate tautomerase activity [GO:0050178]; evasion or tolerance of host immune response [GO:0020012]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	evasion or tolerance of host immune response [GO:0020012]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; host cell cytoplasm [GO:0030430]; Maurer's cleft [GO:0020036]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	cytokine activity [GO:0005125]; host cell surface receptor binding [GO:0046789]; oxidoreductase activity [GO:0016491]; phenylpyruvate tautomerase activity [GO:0050178]
d1p1ga__d4pkza___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d1p1jb2_d2egha3__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; inositol-3-phosphate synthase activity [GO:0004512]; inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	cytoplasm [GO:0005737]		inositol-3-phosphate synthase activity [GO:0004512]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]
d1p1ka2_d2pkrm2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; inositol-3-phosphate synthase activity [GO:0004512]; inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]	inositol-3-phosphate synthase activity [GO:0004512]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1p1qa__d2thia___1	Metazoa		Chordata	Firmicutes	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	extracellular region [GO:0005576]; thiamine pyridinylase activity [GO:0050332]; thiamine catabolic process [GO:0009230]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	thiamine catabolic process [GO:0009230]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	extracellular region [GO:0005576]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	thiamine pyridinylase activity [GO:0050332]
d1p1qc__d3pprb___1	Metazoa		Chordata	Firmicutes	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; amino acid transport [GO:0006865]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	amino acid transport [GO:0006865]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	transmembrane transporter activity [GO:0022857]
d1p1ra2_d1wdlb3__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	fatty acid beta-oxidation [GO:0006635]	cytosol [GO:0005829]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d1p1rc2_d3tfqa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytosol [GO:0005829]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d1p1ub__d1poy1___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; putrescine binding [GO:0019810]; spermidine binding [GO:0019809]; putrescine transport [GO:0015847]; spermidine transport [GO:0015848]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	putrescine transport [GO:0015847]; spermidine transport [GO:0015848]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	putrescine binding [GO:0019810]; spermidine binding [GO:0019809]
d1p1ub__d1sd3a___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d1p1wa__d1jw5a___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1p22b1_d5hywb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; auxin polar transport [GO:0009926]; cuticle development [GO:0042335]; multicellular organism development [GO:0007275]; negative regulation of seed germination [GO:0010187]; positive regulation of response to water deprivation [GO:1902584]; protein ubiquitination [GO:0016567]; regulation of meristem structural organization [GO:0009934]; regulation of shoot system morphogenesis [GO:1900618]; response to light stimulus [GO:0009416]; response to water deprivation [GO:0009414]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; shoot system morphogenesis [GO:0010016]; ubiquitin-dependent protein catabolic process [GO:0006511]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	auxin polar transport [GO:0009926]; cuticle development [GO:0042335]; multicellular organism development [GO:0007275]; negative regulation of seed germination [GO:0010187]; positive regulation of response to water deprivation [GO:1902584]; protein ubiquitination [GO:0016567]; regulation of meristem structural organization [GO:0009934]; regulation of shoot system morphogenesis [GO:1900618]; response to light stimulus [GO:0009416]; response to water deprivation [GO:0009414]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; shoot system morphogenesis [GO:0010016]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]	
d1p28a1_d3d73b___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d1p28b__d3d76a___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d1p2ca1_d2xnaa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1p2ca2_d4fqll1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1p2cb1_d3rgvc2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1p2cd1_d4ydll1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	structural molecule activity [GO:0005198]
d1p2ia__d3sgqe___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1p2ia__d4na9h___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	digestion [GO:0007586]; proteolysis [GO:0006508]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d1p2ra__d1qgia___1				Firmicutes	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; chitosanase activity [GO:0016977]; carbohydrate metabolic process [GO:0005975]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	carbohydrate metabolic process [GO:0005975]	host cell cytoplasm [GO:0030430]	extracellular region [GO:0005576]	lysozyme activity [GO:0003796]	chitosanase activity [GO:0016977]
d1p2ya1_d4hgib___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d1p2za2_d1hx6a2__1					host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]; structural molecule activity [GO:0005198]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]	viral capsid [GO:0019028]; virion [GO:0019012]	microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]		host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]	viral capsid [GO:0019028]; virion [GO:0019012]	structural molecule activity [GO:0005198]	
d1p34c__d4g91b___1	Metazoa	Fungi	Chordata	Ascomycota	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	CCAAT-binding factor complex [GO:0016602]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome positioning [GO:0016584]; regulation of carbohydrate metabolic process [GO:0006109]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]		negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome positioning [GO:0016584]; regulation of carbohydrate metabolic process [GO:0006109]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	CCAAT-binding factor complex [GO:0016602]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]
d1p36a__d1l36a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1p36a__d2g4qa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1p37a__d1zmyl___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1p3ab__d1a7wa___1	Metazoa		Chordata	Euryarchaeota	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; DNA topological change [GO:0006265]; protein homooligomerization [GO:0051260]		DNA topological change [GO:0006265]; protein homooligomerization [GO:0051260]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	double-stranded DNA binding [GO:0003690]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d1p3af__d1kx4d___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1p3ah__d1p3be___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1p3bd__d1bfmb___1	Metazoa		Chordata	Euryarchaeota	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; DNA topological change [GO:0006265]; protein homooligomerization [GO:0051260]		DNA topological change [GO:0006265]; protein homooligomerization [GO:0051260]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	double-stranded DNA binding [GO:0003690]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d1p3bh__d1tafa___1	Metazoa	Metazoa	Chordata	Arthropoda	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleus [GO:0005634]; SAGA complex [GO:0000124]; transcription factor TFIID complex [GO:0005669]; protein heterodimerization activity [GO:0046982]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; histone H3 acetylation [GO:0043966]; ovarian follicle cell development [GO:0030707]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]		histone H3 acetylation [GO:0043966]; ovarian follicle cell development [GO:0030707]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleus [GO:0005634]; SAGA complex [GO:0000124]; transcription factor TFIID complex [GO:0005669]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	protein heterodimerization activity [GO:0046982]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1p3bh__d3afae___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1p3fd__d2pyof___1	Metazoa	Metazoa	Chordata	Arthropoda	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]		chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1p3fe__d1f66d___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1p3fg__d3wa9g___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1p3fh__d1tzyb___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1p3fh__d2bykb1__1	Metazoa	Metazoa	Chordata	Arthropoda	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	CHRAC [GO:0008623]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]; nucleosome mobilization [GO:0042766]		nucleosome mobilization [GO:0042766]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	CHRAC [GO:0008623]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]
d1p3ga__d5g49a1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]; transcription coregulator activity [GO:0003712]; abscisic acid-activated signaling pathway [GO:0009738]; gibberellic acid mediated signaling pathway [GO:0009740]; long-day photoperiodism, flowering [GO:0048574]; positive regulation of photomorphogenesis [GO:2000306]; regulation of seed germination [GO:0010029]		abscisic acid-activated signaling pathway [GO:0009738]; gibberellic acid mediated signaling pathway [GO:0009740]; long-day photoperiodism, flowering [GO:0048574]; positive regulation of photomorphogenesis [GO:2000306]; regulation of seed germination [GO:0010029]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]; transcription coregulator activity [GO:0003712]
d1p3gb__d3afaf___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1p3gb__d4nfta2__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nucleosome [GO:0000786]; nucleus [GO:0005634]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; nucleosomal DNA binding [GO:0031492]; protein heterodimerization activity [GO:0046982]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; cellular response to estradiol stimulus [GO:0071392]; chromatin organization [GO:0006325]; positive regulation of transcription by RNA polymerase II [GO:0045944]		cellular response to estradiol stimulus [GO:0071392]; chromatin organization [GO:0006325]; positive regulation of transcription by RNA polymerase II [GO:0045944]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; nucleosomal DNA binding [GO:0031492]; protein heterodimerization activity [GO:0046982]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d1p3ge__d1p3if___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1p3gh__d3azfg___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1p3hi__d4pj1s___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; zymogen binding [GO:0035375]; cellular response to heat [GO:0034605]; chaperone cofactor-dependent protein refolding [GO:0051085]; regulation of transcription, DNA-templated [GO:0006355]; response to antibiotic [GO:0046677]; response to heat [GO:0009408]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; chaperone cofactor-dependent protein refolding [GO:0051085]; osteoblast differentiation [GO:0001649]; protein folding [GO:0006457]; response to unfolded protein [GO:0006986]	cellular response to heat [GO:0034605]; chaperone cofactor-dependent protein refolding [GO:0051085]; regulation of transcription, DNA-templated [GO:0006355]; response to antibiotic [GO:0046677]; response to heat [GO:0009408]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; chaperone cofactor-dependent protein refolding [GO:0051085]; osteoblast differentiation [GO:0001649]; protein folding [GO:0006457]; response to unfolded protein [GO:0006986]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]
d1p3hn__d1aono___1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; zymogen binding [GO:0035375]; cellular response to heat [GO:0034605]; chaperone cofactor-dependent protein refolding [GO:0051085]; regulation of transcription, DNA-templated [GO:0006355]; response to antibiotic [GO:0046677]; response to heat [GO:0009408]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	cellular response to heat [GO:0034605]; chaperone cofactor-dependent protein refolding [GO:0051085]; regulation of transcription, DNA-templated [GO:0006355]; response to antibiotic [GO:0046677]; response to heat [GO:0009408]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d1p3ib__d5bnvb___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1p3ig__d3c1bd___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1p3ka__d4nftd2__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nucleosome [GO:0000786]; nucleus [GO:0005634]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; nucleosomal DNA binding [GO:0031492]; protein heterodimerization activity [GO:0046982]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; cellular response to estradiol stimulus [GO:0071392]; chromatin organization [GO:0006325]; positive regulation of transcription by RNA polymerase II [GO:0045944]		cellular response to estradiol stimulus [GO:0071392]; chromatin organization [GO:0006325]; positive regulation of transcription by RNA polymerase II [GO:0045944]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; nucleosomal DNA binding [GO:0031492]; protein heterodimerization activity [GO:0046982]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d1p3kf__d2fj7e1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1p3kh__d3azmc___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1p3lh__d1jfib___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714]; negative regulation of transcription by RNA polymerase II [GO:0000122]		negative regulation of transcription by RNA polymerase II [GO:0000122]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transcription coregulator activity [GO:0003712]; transcription corepressor activity [GO:0003714]
d1p3ma__d3a6nb___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of protein oligomerization [GO:0032460]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; telomere capping [GO:0016233]		double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of protein oligomerization [GO:0032460]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; telomere capping [GO:0016233]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1p3me__d4nftb2__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nucleosome [GO:0000786]; nucleus [GO:0005634]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; nucleosomal DNA binding [GO:0031492]; protein heterodimerization activity [GO:0046982]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; cellular response to estradiol stimulus [GO:0071392]; chromatin organization [GO:0006325]; positive regulation of transcription by RNA polymerase II [GO:0045944]		cellular response to estradiol stimulus [GO:0071392]; chromatin organization [GO:0006325]; positive regulation of transcription by RNA polymerase II [GO:0045944]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; nucleosomal DNA binding [GO:0031492]; protein heterodimerization activity [GO:0046982]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d1p3mf__d1p3fb___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1p3na__d4ow1x___1				Actinobacteria	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	host cell cytoplasm [GO:0030430]	extracellular region [GO:0005576]	lysozyme activity [GO:0003796]	hydrolase activity [GO:0016787]
d1p3oe__d5b31g___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1p3og__d5b33g___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1p3oh__d3c1be___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1p3pg__d2aroa___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1p3ra__d4hazb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; clathrin coat of coated pit [GO:0030132]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]; activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	apical plasma membrane [GO:0016324]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol binding [GO:0035091]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1p3va__d1ubba___1		Metazoa	Proteobacteria	Chordata	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	heme oxidation [GO:0006788]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]		caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1p41d1_d4ld5f___1				Firmicutes		DNA-binding transcription factor activity [GO:0003700]						DNA-binding transcription factor activity [GO:0003700]
d1p42b1_d2b9oi1__1			Aquificae		metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]		lipid A biosynthetic process [GO:0009245]				metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]	
d1p43a2_d1l8pa2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1p44b__d2zeab___1			Actinobacteria		cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	
d1p45a__d5pgxe___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d1p48a2_d3qkfb1__1	Fungi		Ascomycota		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	
d1p48b1_d1sjda1__1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	menaquinone biosynthetic process [GO:0009234]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d1p4ac1_d5fd5a___1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; negative regulation of purine nucleobase metabolic process [GO:0045982]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]	negative regulation of purine nucleobase metabolic process [GO:0045982]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleoside metabolic process [GO:0009116]			cytoplasm [GO:0005737]	DNA binding [GO:0003677]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]
d1p4bh__d1dbml1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1p4bh__d5c9jb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1p4ca__d4a3ub___1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; (S)-mandelate dehydrogenase activity [GO:0033720]; FMN binding [GO:0010181]; mandelate catabolic process [GO:0019596]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	mandelate catabolic process [GO:0019596]		membrane [GO:0016020]		(S)-mandelate dehydrogenase activity [GO:0033720]; FMN binding [GO:0010181]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d1p4la1_d4r90l1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1p4la2_d1t21a2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1p4lb__d4l3ce2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1p4ld__d1kg0c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1p4na2_d4cava2__1		Fungi	Firmicutes	Ascomycota	UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity [GO:0047206]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	N-terminal peptidyl-glycine N-myristoylation [GO:0018008]		cytoplasm [GO:0005737]	UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity [GO:0047206]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d1p4rb2_d1uaqa___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]
d1p4xa1_d4ld5c___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]	DNA-binding transcription factor activity [GO:0003700]	pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]		cytoplasm [GO:0005737]		DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]	DNA-binding transcription factor activity [GO:0003700]
d1p50a2_d3l2gi2__1	Metazoa		Arthropoda		cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]		arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	
d1p51b__d4qjnd___1			Cyanobacteria	Firmicutes	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]	chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]	chromosome condensation [GO:0030261]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1p51d__d1owgb___1			Cyanobacteria	Proteobacteria	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]	chromosome [GO:0005694]; cytosol [GO:0005829]; DNA binding [GO:0003677]; conjugation [GO:0000746]; DNA recombination [GO:0006310]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]	chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]	conjugation [GO:0000746]; DNA recombination [GO:0006310]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]		chromosome [GO:0005694]; cytosol [GO:0005829]	DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1p52a1_d3l2gd1__1	Metazoa		Arthropoda		cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]		arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	
d1p53b2_d4wv1d2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1p53b3_d3v4pl2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]	acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; cell migration [GO:0016477]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]
d1p5ba__d3w1rb___1			Proteobacteria		membrane [GO:0016020]; (S)-mandelate dehydrogenase activity [GO:0033720]; FMN binding [GO:0010181]; mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	mandelate catabolic process [GO:0019596]	'de novo' UMP biosynthetic process [GO:0044205]	membrane [GO:0016020]	cytoplasm [GO:0005737]	(S)-mandelate dehydrogenase activity [GO:0033720]; FMN binding [GO:0010181]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d1p5ca__d2razx___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1p5cb__d114la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1p5dx4_d1kfia4__1			Proteobacteria	Ciliophora	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]		cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1p5ed2_d2v22b1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1p5fa__d1ggea1__1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1p5gx3_d1kfib3__1			Proteobacteria	Ciliophora	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]		cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1p5gx4_d1jdyb4__1		Metazoa	Proteobacteria	Chordata	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	glucose metabolic process [GO:0006006]		sarcoplasmic reticulum [GO:0016529]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1p5ja__d1v71a1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; mitochondrion [GO:0005739]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; L-threonine catabolic process to glycine [GO:0019518]; pyruvate biosynthetic process [GO:0042866]; threonine catabolic process [GO:0006567]	ATP binding [GO:0005524]; D-serine ammonia-lyase activity [GO:0008721]; L-serine ammonia-lyase activity [GO:0003941]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; serine racemase activity [GO:0030378]; threonine racemase activity [GO:0018114]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]	gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; L-threonine catabolic process to glycine [GO:0019518]; pyruvate biosynthetic process [GO:0042866]; threonine catabolic process [GO:0006567]	D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]	ATP binding [GO:0005524]; D-serine ammonia-lyase activity [GO:0008721]; L-serine ammonia-lyase activity [GO:0003941]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; serine racemase activity [GO:0030378]; threonine racemase activity [GO:0018114]
d1p5ra__d3ubmc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; formyl-CoA transferase activity [GO:0033608]; oxalate catabolic process [GO:0033611]	formyl-CoA transferase activity [GO:0033608]; oxalate catabolic process [GO:0033611]	oxalate catabolic process [GO:0033611]	oxalate catabolic process [GO:0033611]	cytoplasm [GO:0005737]		formyl-CoA transferase activity [GO:0033608]	formyl-CoA transferase activity [GO:0033608]
d1p5sa__d3hocb1__1	Fungi	Metazoa	Ascomycota	Chordata	actomyosin contractile ring [GO:0005826]; actomyosin contractile ring, proximal layer [GO:0120104]; cytoplasm [GO:0005737]; medial cortical node [GO:0071341]; mitotic actomyosin contractile ring [GO:0110085]; mitotic spindle pole body [GO:0044732]; nuclear envelope [GO:0005635]; spindle pole body [GO:0005816]; actin filament binding [GO:0051015]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; actin filament bundle assembly [GO:0051017]; actin filament bundle convergence involved in mitotic contractile ring assembly [GO:1903478]; division septum assembly [GO:0000917]; mitotic actomyosin contractile ring assembly [GO:1903475]; mitotic actomyosin contractile ring assembly actin filament organization [GO:1903479]; mitotic actomyosin contractile ring localization [GO:1902405]; mitotic contractile ring actin filament bundle assembly [GO:1903477]; negative regulation of actin filament depolymerization [GO:0030835]; positive regulation of actin filament polymerization [GO:0030838]; protein localization to cell division site involved in mitotic actomyosin contractile ring assembly [GO:1903476]; protein localization to medial cortex [GO:0071574]; signal transduction [GO:0007165]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actin filament bundle assembly [GO:0051017]; actin filament bundle convergence involved in mitotic contractile ring assembly [GO:1903478]; division septum assembly [GO:0000917]; mitotic actomyosin contractile ring assembly [GO:1903475]; mitotic actomyosin contractile ring assembly actin filament organization [GO:1903479]; mitotic actomyosin contractile ring localization [GO:1902405]; mitotic contractile ring actin filament bundle assembly [GO:1903477]; negative regulation of actin filament depolymerization [GO:0030835]; positive regulation of actin filament polymerization [GO:0030838]; protein localization to cell division site involved in mitotic actomyosin contractile ring assembly [GO:1903476]; protein localization to medial cortex [GO:0071574]; signal transduction [GO:0007165]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actomyosin contractile ring [GO:0005826]; actomyosin contractile ring, proximal layer [GO:0120104]; cytoplasm [GO:0005737]; medial cortical node [GO:0071341]; mitotic actomyosin contractile ring [GO:0110085]; mitotic spindle pole body [GO:0044732]; nuclear envelope [GO:0005635]; spindle pole body [GO:0005816]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	actin filament binding [GO:0051015]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d1p5ub__d2jkjf1__1			Proteobacteria	Proteobacteria	capsule [GO:0042603]; extracellular region [GO:0005576]	pilus [GO:0009289]			capsule [GO:0042603]; extracellular region [GO:0005576]	pilus [GO:0009289]		
d1p5vb__d1kiuf2__1			Proteobacteria	Proteobacteria	capsule [GO:0042603]; extracellular region [GO:0005576]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	capsule [GO:0042603]; extracellular region [GO:0005576]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d1p5xa__d5fb9a___1		Fungi	Firmicutes	Ascomycota	phosphatidylcholine phospholipase C activity [GO:0034480]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleic acid binding [GO:0003676]; DNA catabolic process [GO:0006308]	hemolysis in other organism [GO:0044179]	DNA catabolic process [GO:0006308]			phosphatidylcholine phospholipase C activity [GO:0034480]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleic acid binding [GO:0003676]
d1p60a__d1jeea3__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; deoxycytidine kinase activity [GO:0004137]; deoxynucleoside kinase activity [GO:0019136]; drug binding [GO:0008144]; protein homodimerization activity [GO:0042803]; purine-containing compound salvage [GO:0043101]; pyrimidine nucleoside salvage [GO:0043097]; pyrimidine nucleotide metabolic process [GO:0006220]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	purine-containing compound salvage [GO:0043101]; pyrimidine nucleoside salvage [GO:0043097]; pyrimidine nucleotide metabolic process [GO:0006220]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; deoxycytidine kinase activity [GO:0004137]; deoxynucleoside kinase activity [GO:0019136]; drug binding [GO:0008144]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1p63b__d1jy0a1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1p64a__d3c82a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1p69a__d1uxab___1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	viral capsid [GO:0019028]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	metal ion binding [GO:0046872]
d1p69b1_d2hwzl1__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d1p6aa__d3bq4b___1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	viral capsid [GO:0019028]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d1p6aa__d3f0yg___1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	viral capsid [GO:0019028]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d1p6da__d1olpc1__1			Firmicutes	Firmicutes	phosphatidylcholine phospholipase C activity [GO:0034480]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	phospholipase C activity [GO:0004629]; zinc ion binding [GO:0008270]	hemolysis in other organism [GO:0044179]				phosphatidylcholine phospholipase C activity [GO:0034480]; zinc ion binding [GO:0008270]	phospholipase C activity [GO:0004629]; zinc ion binding [GO:0008270]
d1p6fa1_d1cu4l2__1	Metazoa		Chordata		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; SWI/SNF complex [GO:0016514]; cellular defense response [GO:0006968]; natural killer cell activation [GO:0030101]; regulation of immune response [GO:0050776]; regulation of natural killer cell mediated cytotoxicity [GO:0042269]; signal transduction [GO:0007165]		cellular defense response [GO:0006968]; natural killer cell activation [GO:0030101]; regulation of immune response [GO:0050776]; regulation of natural killer cell mediated cytotoxicity [GO:0042269]; signal transduction [GO:0007165]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; SWI/SNF complex [GO:0016514]			
d1p6fa2_d3g6al2__1	Metazoa		Chordata		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; SWI/SNF complex [GO:0016514]; cellular defense response [GO:0006968]; natural killer cell activation [GO:0030101]; regulation of immune response [GO:0050776]; regulation of natural killer cell mediated cytotoxicity [GO:0042269]; signal transduction [GO:0007165]		cellular defense response [GO:0006968]; natural killer cell activation [GO:0030101]; regulation of immune response [GO:0050776]; regulation of natural killer cell mediated cytotoxicity [GO:0042269]; signal transduction [GO:0007165]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; SWI/SNF complex [GO:0016514]			
d1p6oa__d1ysdb2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]
d1p6ob1_d1ysba1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]
d1p6ob1_d5k81f___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; innate immune response [GO:0045087]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	base conversion or substitution editing [GO:0016553]; innate immune response [GO:0045087]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]
d1p6pa__d1towa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; lipid binding [GO:0008289]; lipid transport [GO:0006869]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	lipid transport [GO:0006869]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	lipid binding [GO:0008289]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1p6pa__d3np1a___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; lipid binding [GO:0008289]; lipid transport [GO:0006869]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	lipid transport [GO:0006869]	vasodilation [GO:0042311]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	lipid binding [GO:0008289]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]
d1p6ra__d4a2ue2__1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1p6ta2_d1jk9d2__1		Fungi	Firmicutes	Ascomycota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; identical protein binding [GO:0042802]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]		age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; identical protein binding [GO:0042802]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]
d1p6ua__d4le1b___1			Proteobacteria	Firmicutes	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]		cytoplasm [GO:0005737]		DNA binding [GO:0003677]
d1p71a__d5lvta___1			Cyanobacteria	Firmicutes	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]	chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]	chromosome condensation [GO:0030261]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1p74a2_d1gtma2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d1p74b2_d3wjab1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; manganese ion binding [GO:0030145]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxaloacetate decarboxylase activity [GO:0008948]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; nucleotide biosynthetic process [GO:0009165]; pyruvate metabolic process [GO:0006090]; regulation of lipid metabolic process [GO:0019216]; regulation of NADP metabolic process [GO:1902031]; response to carbohydrate [GO:0009743]; response to hormone [GO:0009725]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; nucleotide biosynthetic process [GO:0009165]; pyruvate metabolic process [GO:0006090]; regulation of lipid metabolic process [GO:0019216]; regulation of NADP metabolic process [GO:1902031]; response to carbohydrate [GO:0009743]; response to hormone [GO:0009725]	cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	ADP binding [GO:0043531]; electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; manganese ion binding [GO:0030145]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxaloacetate decarboxylase activity [GO:0008948]
d1p78a__d4pt4b___1			Cyanobacteria	Actinobacteria	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; double-stranded DNA binding [GO:0003690]; supercoiled DNA binding [GO:0097100]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; cellular response to iron ion starvation [GO:0010106]; chromosome condensation [GO:0030261]; DNA protection [GO:0042262]; nucleoid organization [GO:0090143]; positive regulation of transcription, DNA-templated [GO:0045893]	chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]	cellular response to iron ion starvation [GO:0010106]; chromosome condensation [GO:0030261]; DNA protection [GO:0042262]; nucleoid organization [GO:0090143]; positive regulation of transcription, DNA-templated [GO:0045893]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; double-stranded DNA binding [GO:0003690]; supercoiled DNA binding [GO:0097100]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1p78b__d4dkya___1			Cyanobacteria	Actinobacteria	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; double-stranded DNA binding [GO:0003690]; supercoiled DNA binding [GO:0097100]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; cellular response to iron ion starvation [GO:0010106]; chromosome condensation [GO:0030261]; DNA protection [GO:0042262]; nucleoid organization [GO:0090143]; positive regulation of transcription, DNA-templated [GO:0045893]	chromosome condensation [GO:0030261]; heterocyst differentiation [GO:0043158]	cellular response to iron ion starvation [GO:0010106]; chromosome condensation [GO:0030261]; DNA protection [GO:0042262]; nucleoid organization [GO:0090143]; positive regulation of transcription, DNA-templated [GO:0045893]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; double-stranded DNA binding [GO:0003690]; supercoiled DNA binding [GO:0097100]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1p7hl1_d2i9tb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1p7hl1_d4utca2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	protein dimerization activity [GO:0046983]
d1p7hm2_d1vkxa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1p7hm2_d2h1lq2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1p7hn1_d1gjia1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; apoptotic DNA fragmentation [GO:0006309]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	apoptotic DNA fragmentation [GO:0006309]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d1p7hn1_d3r18a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]
d1p7ho1_d2r29a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1p7ka2_d4ypga2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]
d1p7kh1_d1ngwh2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1p7kl2_d4ouoa1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1p7lb2_d4ndnc3__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d1p7lc1_d4ndnb2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d1p7ld2_d3tdeb1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]
d1p7qa1_d1lilb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1p7zb1_d3sf8b___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]
d1p80c1_d2or3a___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]
d1p80d1_d4y1ea1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]		cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	
d1p81a1_d3p9qa2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1p81c1_d1sy7b1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	ascospore wall [GO:0005619]; cytosol [GO:0005829]; extracellular region [GO:0005576]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; conidium formation [GO:0048315]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	conidium formation [GO:0048315]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ascospore wall [GO:0005619]; cytosol [GO:0005829]; extracellular region [GO:0005576]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1p84d1_d1bccd2__1	Fungi	Metazoa	Ascomycota	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1p84k__d3c60d1__1	Fungi	Metazoa	Ascomycota	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d1p8fa__d5grhb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; ATP binding [GO:0005524]; isocitrate dehydrogenase (NAD+) activity [GO:0004449]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	ATP binding [GO:0005524]; isocitrate dehydrogenase (NAD+) activity [GO:0004449]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1p8ja1_d1ot5b1__1	Metazoa	Fungi	Chordata	Ascomycota	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]	dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]	fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1p8jb1_d3hpnf___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]
d1p8jd1_d1l7ra1__1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	cocaine catabolic process [GO:0050784]	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]	cytoplasm [GO:0005737]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]
d1p8jg2_d1siob___1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1p8jh1_d2qqia2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]; coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]	coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d1p8jh2_d1tm5e1__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1p8la2_d1ckna2__1					ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]	GTP binding [GO:0005525]; mRNA guanylyltransferase activity [GO:0004484]; 7-methylguanosine mRNA capping [GO:0006370]	DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]	7-methylguanosine mRNA capping [GO:0006370]			ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]	GTP binding [GO:0005525]; mRNA guanylyltransferase activity [GO:0004484]
d1p8ma__d2phob___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1p8na__d5wgma1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]
d1p8nc__d1woha1__1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	agmatinase activity [GO:0008783]; metal ion binding [GO:0046872]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	agmatinase activity [GO:0008783]; metal ion binding [GO:0046872]
d1p8oa__d1tblc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1p8ta__d1m10b___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; axonogenesis [GO:0007409]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	axonogenesis [GO:0007409]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative regulation of axon extension [GO:0030517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d1p8v.1_d2cjia___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1p8xc2_d1mdud___1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1p8xc2_d3fg6b2__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]
d1p8xc3_d1hqz4___1	Metazoa	Fungi	Chordata	Ascomycota	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin filament binding [GO:0051015]; actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin filament binding [GO:0051015]
d1p98a__d5cx3c___1	Metazoa	Metazoa	Chordata	Chordata	centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; damaged DNA binding [GO:0003684]; kinase binding [GO:0019900]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; single-stranded DNA binding [GO:0003697]; ubiquitin binding [GO:0043130]; ubiquitin-specific protease binding [GO:1990381]; nucleotide-excision repair [GO:0006289]; positive regulation of cell cycle [GO:0045787]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of viral genome replication [GO:0045070]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; viral process [GO:0016032]	autolysosome [GO:0044754]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; microtubule [GO:0005874]; organelle membrane [GO:0031090]; synapse [GO:0045202]; microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; phospholipid binding [GO:0005543]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]	nucleotide-excision repair [GO:0006289]; positive regulation of cell cycle [GO:0045787]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of viral genome replication [GO:0045070]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; viral process [GO:0016032]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]	centriolar satellite [GO:0034451]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]	autolysosome [GO:0044754]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; microtubule [GO:0005874]; organelle membrane [GO:0031090]; synapse [GO:0045202]	damaged DNA binding [GO:0003684]; kinase binding [GO:0019900]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; single-stranded DNA binding [GO:0003697]; ubiquitin binding [GO:0043130]; ubiquitin-specific protease binding [GO:1990381]	microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; phospholipid binding [GO:0005543]; ubiquitin protein ligase binding [GO:0031625]
d1p9ag__d1gwba___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; thrombin-activated receptor activity [GO:0015057]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; thrombin-activated receptor activity [GO:0015057]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	thrombin-activated receptor activity [GO:0015057]	thrombin-activated receptor activity [GO:0015057]
d1p9ag__d1kooc1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; thrombin-activated receptor activity [GO:0015057]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	thrombin-activated receptor activity [GO:0015057]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1p9ba__d2q21a___1		Metazoa	Apicomplexa	Chordata	cytoplasm [GO:0005737]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; 'de novo' AMP biosynthetic process [GO:0044208]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	'de novo' AMP biosynthetic process [GO:0044208]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1p9ea__d1bmib___1			Proteobacteria		hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]						hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	
d1p9eb__d5ev6a___1			Proteobacteria	Proteobacteria	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d1p9mc2_d4o00a1__1	Metazoa	Metazoa	Chordata	Chordata	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1p9ua__d1owka___1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]
d1p9uc__d1fq3a___1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; natural killer cell mediated cytotoxicity [GO:0042267]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; natural killer cell mediated cytotoxicity [GO:0042267]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1pa0a__d3cxib___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]
d1pa0a__d3vc0a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]
d1pa2a1_d1h5ia___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; defense response to nematode [GO:0002215]; flower development [GO:0009908]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	defense response to nematode [GO:0002215]; flower development [GO:0009908]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]	extracellular region [GO:0005576]; vacuole [GO:0005773]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1pa2a1_d1pggb1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; defense response to nematode [GO:0002215]; flower development [GO:0009908]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	defense response to nematode [GO:0002215]; flower development [GO:0009908]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1pa3a2_d3zvjn___1		Metazoa	Apicomplexa	Platyhelminthes	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]	glutathione transferase activity [GO:0004364]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1pa3b2_d1o8xa___1			Apicomplexa		glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]	glutathione transferase activity [GO:0004364]	
d1pa6a3_d1t9ha1__1			Ciliophora	Firmicutes	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; rRNA binding [GO:0019843]; ribosomal small subunit biogenesis [GO:0042274]	telomere capping [GO:0016233]	ribosomal small subunit biogenesis [GO:0042274]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	cytoplasm [GO:0005737]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; rRNA binding [GO:0019843]
d1paga__d4zfua___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1pagb__d1j4ga___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]	defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1pama1_d1j0jb1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1pamb1_d1goha1__1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]
d1pamb1_d2hg0a2__1			Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	protein dimerization activity [GO:0046983]
d1pamb3_d1uh2a2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1pamb4_d1jz1l5__1			Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	
d1pb6b3_d2da6a1__1		Metazoa		Chordata		intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; proximal promoter sequence-specific DNA binding [GO:0000987]; anterior/posterior pattern specification [GO:0009952]; branching morphogenesis of an epithelial tube [GO:0048754]; circadian regulation of gene expression [GO:0032922]; embryonic digestive tract morphogenesis [GO:0048557]; endocrine pancreas development [GO:0031018]; endodermal cell fate specification [GO:0001714]; epithelial cell proliferation [GO:0050673]; genitalia development [GO:0048806]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; hindbrain development [GO:0030902]; inner cell mass cell differentiation [GO:0001826]; insulin secretion [GO:0030073]; kidney development [GO:0001822]; mesonephric duct formation [GO:0072181]; negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis [GO:0061296]; negative regulation of mesenchymal cell apoptotic process involved in metanephros development [GO:1900212]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of transcription, DNA-templated [GO:0045893]; pronephric nephron tubule development [GO:0039020]; pronephros development [GO:0048793]; protein-DNA complex assembly [GO:0065004]; regulation of branch elongation involved in ureteric bud branching [GO:0072095]; regulation of pronephros size [GO:0035565]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to organic cyclic compound [GO:0014070]; ureteric bud elongation [GO:0060677]		anterior/posterior pattern specification [GO:0009952]; branching morphogenesis of an epithelial tube [GO:0048754]; circadian regulation of gene expression [GO:0032922]; embryonic digestive tract morphogenesis [GO:0048557]; endocrine pancreas development [GO:0031018]; endodermal cell fate specification [GO:0001714]; epithelial cell proliferation [GO:0050673]; genitalia development [GO:0048806]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; hindbrain development [GO:0030902]; inner cell mass cell differentiation [GO:0001826]; insulin secretion [GO:0030073]; kidney development [GO:0001822]; mesonephric duct formation [GO:0072181]; negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis [GO:0061296]; negative regulation of mesenchymal cell apoptotic process involved in metanephros development [GO:1900212]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; pronephric nephron tubule development [GO:0039020]; pronephros development [GO:0048793]; protein-DNA complex assembly [GO:0065004]; regulation of branch elongation involved in ureteric bud branching [GO:0072095]; regulation of pronephros size [GO:0035565]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to organic cyclic compound [GO:0014070]; ureteric bud elongation [GO:0060677]		intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; proximal promoter sequence-specific DNA binding [GO:0000987]
d1pb6b3_d2xpua1__1				Proteobacteria		DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]				DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d1pb6b4_d3btje2__1				Firmicutes		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]		negative regulation of transcription, DNA-templated [GO:0045892]				DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1pb6c3_d4j19a___1		Metazoa		Chordata		Cajal body [GO:0015030]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded telomeric DNA binding [GO:0003691]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; sequence-specific DNA binding [GO:0043565]; telomeric DNA binding [GO:0042162]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of chromatin binding [GO:0035563]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of telomerase activity [GO:0051972]		negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of chromatin binding [GO:0035563]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of telomerase activity [GO:0051972]		Cajal body [GO:0015030]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]		DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded telomeric DNA binding [GO:0003691]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; sequence-specific DNA binding [GO:0043565]; telomeric DNA binding [GO:0042162]
d1pbka__d3odka2__1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]		cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]
d1pbka__d5hw8a___1	Metazoa	Fungi	Chordata	Ascomycota	nucleus [GO:0005634]; FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]	cytoplasm [GO:0005737]; fungal biofilm matrix [GO:0062040]; drug binding [GO:0008144]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; cellular response to drug [GO:0035690]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]		cellular response to drug [GO:0035690]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; fungal biofilm matrix [GO:0062040]	FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]	drug binding [GO:0008144]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1pbob__d2cbra___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinol binding [GO:0019841]; protein homooligomerization [GO:0051260]; retinoic acid catabolic process [GO:0034653]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	protein homooligomerization [GO:0051260]; retinoic acid catabolic process [GO:0034653]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	small molecule binding [GO:0036094]	identical protein binding [GO:0042802]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinol binding [GO:0019841]
d1pbwa__d1wera___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]; 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; insulin binding [GO:0043559]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; insulin-like growth factor receptor binding [GO:0005159]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; axon guidance [GO:0007411]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTPase binding [GO:0051020]; phosphotyrosine residue binding [GO:0001784]; potassium channel inhibitor activity [GO:0019870]; signaling receptor binding [GO:0005102]; blood vessel morphogenesis [GO:0048514]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Ras protein signal transduction [GO:0046580]; regulation of actin filament polymerization [GO:0030833]; regulation of cell shape [GO:0008360]; regulation of RNA metabolic process [GO:0051252]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570]	axon guidance [GO:0007411]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; platelet activation [GO:0030168]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	blood vessel morphogenesis [GO:0048514]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Ras protein signal transduction [GO:0046580]; regulation of actin filament polymerization [GO:0030833]; regulation of cell shape [GO:0008360]; regulation of RNA metabolic process [GO:0051252]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570]	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle [GO:0001726]	1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; insulin binding [GO:0043559]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTPase binding [GO:0051020]; phosphotyrosine residue binding [GO:0001784]; potassium channel inhibitor activity [GO:0019870]; signaling receptor binding [GO:0005102]
d1pbwb__d1am4b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]; 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; insulin binding [GO:0043559]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; insulin-like growth factor receptor binding [GO:0005159]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; axon guidance [GO:0007411]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	axon guidance [GO:0007411]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; platelet activation [GO:0030168]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; insulin binding [GO:0043559]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]
d1pbxb__d1fn3b___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1pbxb__d3wcvb___1	Metazoa	Metazoa	Chordata	Annelida	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1pbya4_d2d0ga1__1			Proteobacteria	Firmicutes	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1pbya5_d1jmxa5__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1pc8b1_d1upsa2__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1pcaa1_d3co0p1__1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	proteolysis [GO:0006508]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular space [GO:0005615]	extracellular region [GO:0005576]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1pcic__d1yt7a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cysteine-type peptidase activity [GO:0008234]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]		autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]		endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	cysteine-type peptidase activity [GO:0008234]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d1pcjx4_d3c04a4__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]			magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]
d1pcla__d1o8fa___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	pectin catabolic process [GO:0045490]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]
d1pcla__d2nt9b___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	pectin catabolic process [GO:0045490]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]
d1pcqe2_d1q3sf2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1pcza1_d3cwaa2__1			Euryarchaeota	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1pczb2_d1volb2__1		Viridiplantae	Euryarchaeota	Streptophyta	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]		nucleus [GO:0005634]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1pd211_d1q4ja1__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; glutathione metabolic process [GO:0006749]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693]	glutathione transferase activity [GO:0004364]	glutathione metabolic process [GO:0006749]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693]		cytoplasm [GO:0005737]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d1pd212_d3hjpc1__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; glutathione metabolic process [GO:0006749]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693]	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	glutathione metabolic process [GO:0006749]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]	cell [GO:0005623]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]
d1pd221_d1aqxa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; glutathione metabolic process [GO:0006749]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1pd5a__d2ii4g___1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	response to antibiotic [GO:0046677]			cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	chloramphenicol O-acetyltransferase activity [GO:0008811]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1pd5b__d2ii3e___1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	response to antibiotic [GO:0046677]			cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	chloramphenicol O-acetyltransferase activity [GO:0008811]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1pd5d__d1claa___1			Proteobacteria	Proteobacteria	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]			chloramphenicol O-acetyltransferase activity [GO:0008811]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d1pd5f__d2h3wa1__1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	response to antibiotic [GO:0046677]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]		endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	chloramphenicol O-acetyltransferase activity [GO:0008811]	carnitine O-acetyltransferase activity [GO:0004092]
d1pd5h__d2ihwh___1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	response to antibiotic [GO:0046677]			cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	chloramphenicol O-acetyltransferase activity [GO:0008811]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1pd5i__d2fy3a2__1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleus [GO:0005634]; presynapse [GO:0098793]; choline O-acetyltransferase activity [GO:0004102]; acetylcholine biosynthetic process [GO:0008292]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; phosphatidylcholine biosynthetic process [GO:0006656]	response to antibiotic [GO:0046677]	acetylcholine biosynthetic process [GO:0008292]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; phosphatidylcholine biosynthetic process [GO:0006656]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleus [GO:0005634]; presynapse [GO:0098793]	chloramphenicol O-acetyltransferase activity [GO:0008811]	choline O-acetyltransferase activity [GO:0004102]
d1pd5k__d2ihwd___1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	response to antibiotic [GO:0046677]			cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	chloramphenicol O-acetyltransferase activity [GO:0008811]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1pd6a__d1j87a2__1	Metazoa	Metazoa	Chordata	Chordata	A band [GO:0031672]; C zone [GO:0014705]; cardiac myofibril [GO:0097512]; cytosol [GO:0005829]; sarcomere [GO:0030017]; striated muscle myosin thick filament [GO:0005863]; actin binding [GO:0003779]; ATPase activator activity [GO:0001671]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; myosin heavy chain binding [GO:0032036]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	Fc-epsilon receptor signaling pathway [GO:0038095]	A band [GO:0031672]; cardiac myofibril [GO:0097512]; cytosol [GO:0005829]; C zone [GO:0014705]; sarcomere [GO:0030017]; striated muscle myosin thick filament [GO:0005863]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	actin binding [GO:0003779]; ATPase activator activity [GO:0001671]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; myosin heavy chain binding [GO:0032036]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	IgE binding [GO:0019863]
d1pd6a__d4llaa2__1	Metazoa	Metazoa	Chordata	Chordata	A band [GO:0031672]; C zone [GO:0014705]; cardiac myofibril [GO:0097512]; cytosol [GO:0005829]; sarcomere [GO:0030017]; striated muscle myosin thick filament [GO:0005863]; actin binding [GO:0003779]; ATPase activator activity [GO:0001671]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; myosin heavy chain binding [GO:0032036]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cell adhesion molecule binding [GO:0050839]; inhibitory MHC class I receptor activity [GO:0032396]; MHC class I protein binding [GO:0042288]; MHC class Ib protein binding [GO:0023029]; MHC class Ib protein complex binding [GO:0023025]; protein homodimerization activity [GO:0042803]; protein phosphatase 1 binding [GO:0008157]; protein-containing complex binding [GO:0044877]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; cellular response to lipopolysaccharide [GO:0071222]; Fc receptor mediated inhibitory signaling pathway [GO:0002774]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; immune response-inhibiting cell surface receptor signaling pathway [GO:0002767]; learning or memory [GO:0007611]; negative regulation of antigen processing and presentation [GO:0002578]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of postsynaptic density organization [GO:1905875]; negative regulation of protein metabolic process [GO:0051248]; negative regulation of T cell proliferation [GO:0042130]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T cell tolerance induction [GO:0002666]; positive regulation of tolerance induction [GO:0002645]; regulation of dendritic cell differentiation [GO:2001198]; regulation of immune response [GO:0050776]; regulation of long-term synaptic potentiation [GO:1900271]; signal transduction [GO:0007165]	cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	adaptive immune response [GO:0002250]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to lipopolysaccharide [GO:0071222]; Fc receptor mediated inhibitory signaling pathway [GO:0002774]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; immune response-inhibiting cell surface receptor signaling pathway [GO:0002767]; learning or memory [GO:0007611]; negative regulation of antigen processing and presentation [GO:0002578]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of postsynaptic density organization [GO:1905875]; negative regulation of protein metabolic process [GO:0051248]; negative regulation of T cell proliferation [GO:0042130]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T cell tolerance induction [GO:0002666]; positive regulation of tolerance induction [GO:0002645]; regulation of dendritic cell differentiation [GO:2001198]; regulation of immune response [GO:0050776]; regulation of long-term synaptic potentiation [GO:1900271]; signal transduction [GO:0007165]	A band [GO:0031672]; cardiac myofibril [GO:0097512]; cytosol [GO:0005829]; C zone [GO:0014705]; sarcomere [GO:0030017]; striated muscle myosin thick filament [GO:0005863]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	actin binding [GO:0003779]; ATPase activator activity [GO:0001671]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; myosin heavy chain binding [GO:0032036]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	amyloid-beta binding [GO:0001540]; cell adhesion molecule binding [GO:0050839]; inhibitory MHC class I receptor activity [GO:0032396]; MHC class Ib protein binding [GO:0023029]; MHC class Ib protein complex binding [GO:0023025]; MHC class I protein binding [GO:0042288]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; protein phosphatase 1 binding [GO:0008157]
d1pdaa2_d5ov5a2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; hydroxymethylbilane synthase activity [GO:0004418]; heme biosynthetic process [GO:0006783]; peptidyl-pyrromethane cofactor linkage [GO:0018160]; protoporphyrinogen IX biosynthetic process [GO:0006782]; tetrapyrrole biosynthetic process [GO:0033014]	hydroxymethylbilane synthase activity [GO:0004418]; peptidyl-pyrromethane cofactor linkage [GO:0018160]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; peptidyl-pyrromethane cofactor linkage [GO:0018160]; protoporphyrinogen IX biosynthetic process [GO:0006782]; tetrapyrrole biosynthetic process [GO:0033014]	peptidyl-pyrromethane cofactor linkage [GO:0018160]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		hydroxymethylbilane synthase activity [GO:0004418]	hydroxymethylbilane synthase activity [GO:0004418]
d1pdua1_d1gwxb___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; core promoter binding [GO:0001047]; glucocorticoid receptor binding [GO:0035259]; nuclear receptor activity [GO:0004879]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; signaling receptor binding [GO:0005102]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]; cellular response to corticotropin-releasing hormone stimulus [GO:0071376]; cuticle development [GO:0042335]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of adult chitin-containing cuticle pigmentation [GO:0048082]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; linoleic acid binding [GO:0070539]; lipid binding [GO:0008289]; NF-kappaB binding [GO:0051059]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; axon ensheathment [GO:0008366]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular response to hypoxia [GO:0071456]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol metabolic process [GO:0008203]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; glucose metabolic process [GO:0006006]; glucose transmembrane transport [GO:1904659]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; keratinocyte migration [GO:0051546]; keratinocyte proliferation [GO:0043616]; lipid metabolic process [GO:0006629]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; phospholipid biosynthetic process [GO:0008654]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of epidermis development [GO:0045684]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of insulin secretion [GO:0032024]; positive regulation of myoblast proliferation [GO:2000288]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of skeletal muscle tissue regeneration [GO:0043415]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; proteoglycan metabolic process [GO:0006029]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle satellite cell proliferation [GO:0014842]; regulation of transcription by RNA polymerase II [GO:0006357]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to lipid [GO:0033993]; response to vitamin A [GO:0033189]; transcription initiation from RNA polymerase II promoter [GO:0006367]; vitamin A metabolic process [GO:0006776]; wound healing [GO:0042060]	cellular response to corticotropin-releasing hormone stimulus [GO:0071376]; cuticle development [GO:0042335]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of adult chitin-containing cuticle pigmentation [GO:0048082]	adipose tissue development [GO:0060612]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; axon ensheathment [GO:0008366]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular response to hypoxia [GO:0071456]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol metabolic process [GO:0008203]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; glucose metabolic process [GO:0006006]; glucose transmembrane transport [GO:1904659]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; keratinocyte migration [GO:0051546]; keratinocyte proliferation [GO:0043616]; lipid metabolic process [GO:0006629]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phospholipid biosynthetic process [GO:0008654]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of epidermis development [GO:0045684]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of insulin secretion [GO:0032024]; positive regulation of myoblast proliferation [GO:2000288]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of skeletal muscle tissue regeneration [GO:0043415]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteoglycan metabolic process [GO:0006029]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle satellite cell proliferation [GO:0014842]; regulation of transcription by RNA polymerase II [GO:0006357]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to lipid [GO:0033993]; response to vitamin A [GO:0033189]; transcription initiation from RNA polymerase II promoter [GO:0006367]; vitamin A metabolic process [GO:0006776]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]	core promoter binding [GO:0001047]; glucocorticoid receptor binding [GO:0035259]; nuclear receptor activity [GO:0004879]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; signaling receptor binding [GO:0005102]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; linoleic acid binding [GO:0070539]; lipid binding [GO:0008289]; NF-kappaB binding [GO:0051059]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]
d1pe0b__d1izya___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cytosol [GO:0005829]; glyoxalase III activity [GO:0019172]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; protein deglycase activity [GO:0036524]; thiolester hydrolase activity [GO:0016790]; zinc ion binding [GO:0008270]; DNA repair [GO:0006281]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to acidic pH [GO:0010447]; response to methylglyoxal [GO:0051595]; RNA repair [GO:0042245]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	DNA repair [GO:0006281]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to acidic pH [GO:0010447]; response to methylglyoxal [GO:0051595]; RNA repair [GO:0042245]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]	cytosol [GO:0005829]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]	glyoxalase III activity [GO:0019172]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; protein deglycase activity [GO:0036524]; thiolester hydrolase activity [GO:0016790]; zinc ion binding [GO:0008270]
d1pe5a__d5givc___1			Firmicutes	Deinococcus-Thermus	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metallocarboxypeptidase activity [GO:0004181]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metallocarboxypeptidase activity [GO:0004181]
d1pe6a__d1qmyc___1	Viridiplantae		Streptophyta		cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1pe9a__d1o8ea___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	pectin catabolic process [GO:0045490]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]
d1pe9a__d1qcxa___1		Fungi	Proteobacteria	Ascomycota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; pectin lyase activity [GO:0047490]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	pectin catabolic process [GO:0045490]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	pectin lyase activity [GO:0047490]
d1pe9b__d1rmga___1		Fungi	Proteobacteria	Ascomycota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	pectin catabolic process [GO:0045490]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	polygalacturonase activity [GO:0004650]
d1peba__d3vvda1__1			Proteobacteria	Deinococcus-Thermus	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	membrane [GO:0016020]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	ligand-gated ion channel activity [GO:0015276]
d1pedb2_d5u1pa___1			Firmicutes	Proteobacteria	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	carbonyl reductase (NADPH) activity [GO:0004090]; nucleotide binding [GO:0000166]					isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	carbonyl reductase (NADPH) activity [GO:0004090]; nucleotide binding [GO:0000166]
d1pedc2_d3gr6j1__1			Firmicutes	Firmicutes	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity [GO:0047117]; NADP binding [GO:0050661]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]		fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]			isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity [GO:0047117]; NADP binding [GO:0050661]
d1peea1_d5hz9a1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	vasodilation [GO:0042311]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]
d1peke__d1kdza___1	Fungi		Ascomycota		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]						metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	
d1peua1_d6r1rc1__1			Proteobacteria	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; ATP binding [GO:0005524]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ATP binding [GO:0005524]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1peva2_d4ukxg___1	Metazoa		Nematoda (roundworms)		actomyosin, actin portion [GO:0042643]; cortical actin cytoskeleton [GO:0030864]; myofibril [GO:0030016]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin filament depolymerization [GO:0030042]; locomotion [GO:0040011]; muscle thin filament assembly [GO:0071689]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of actin filament depolymerization [GO:0030836]; regulation of locomotion [GO:0040012]; sarcomere organization [GO:0045214]; skeletal muscle thin filament assembly [GO:0030240]		actin filament depolymerization [GO:0030042]; locomotion [GO:0040011]; muscle thin filament assembly [GO:0071689]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of actin filament depolymerization [GO:0030836]; regulation of locomotion [GO:0040012]; sarcomere organization [GO:0045214]; skeletal muscle thin filament assembly [GO:0030240]		actomyosin, actin portion [GO:0042643]; cortical actin cytoskeleton [GO:0030864]; myofibril [GO:0030016]; sarcoplasm [GO:0016528]		actin binding [GO:0003779]; actin filament binding [GO:0051015]	
d1peza4_d4re3a1__1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1pf9d2_d1q2vd2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1pf9e2_d1asxa___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1pf9n2_d1oelc3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]
d1pfga__d2pyza___1	Fungi	Fungi	Ascomycota	Ascomycota	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1pfja__d4zrkb3__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]; chromatin binding [GO:0003682]; 7-methylguanosine mRNA capping [GO:0006370]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase I promoter [GO:0006361]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription-coupled nucleotide-excision repair [GO:0006283]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	7-methylguanosine mRNA capping [GO:0006370]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	nucleoplasm [GO:0005654]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	chromatin binding [GO:0003682]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d1pfmc__d1f9qc___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]; chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]; chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]	chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]	chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]
d1pfua1_d1jzsa1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; isoleucyl-tRNA aminoacylation [GO:0006428]	methionyl-tRNA aminoacylation [GO:0006431]	isoleucyl-tRNA aminoacylation [GO:0006428]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1pfxc__d1ql9a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	blood coagulation [GO:0007596]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]
d1pg5a2_d4h31c2__1			Crenarchaeota	Proteobacteria	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]	arginine biosynthetic process [GO:0006526]		cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1pg7h1_d4pjhe1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1pg7i1_d4s1dp1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1pg7l1_d4yhml2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1pg7m1_d5eiib1__1	Metazoa	Fungi	Chordata	Ascomycota	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleus [GO:0005634]; histone binding [GO:0042393]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H2B ubiquitination [GO:0033523]; nucleosome disassembly [GO:0006337]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of gene expression [GO:0010468]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H2B ubiquitination [GO:0033523]; nucleosome disassembly [GO:0006337]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of gene expression [GO:0010468]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleus [GO:0005634]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	histone binding [GO:0042393]
d1pg7m2_d3a6cl___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1pg7w2_d3haee1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytoplasm [GO:0005737]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1pg7x1_d1bbdh1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	immune response [GO:0006955]; immunoglobulin production [GO:0002377]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d1pg7y1_d1vadb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1pg7z1_d2dtgb1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1pg8b__d1n8pa___1		Fungi	Proteobacteria	Ascomycota	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; carbon-sulfur lyase activity [GO:0016846]; cystathionine gamma-lyase activity [GO:0004123]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; L-cystine L-cysteine-lyase (deaminating) [GO:0044540]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process via cystathionine [GO:0019343]; transsulfuration [GO:0019346]	transsulfuration [GO:0019346]	cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process via cystathionine [GO:0019343]; transsulfuration [GO:0019346]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]	carbon-sulfur lyase activity [GO:0016846]; cystathionine gamma-lyase activity [GO:0004123]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; L-cystine L-cysteine-lyase (deaminating) [GO:0044540]; pyridoxal phosphate binding [GO:0030170]
d1pg8c__d3fslc___1			Proteobacteria	Proteobacteria	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aromatic-amino-acid:2-oxoglutarate aminotransferase activity [GO:0008793]; identical protein binding [GO:0042802]; L-leucine:2-oxoglutarate aminotransferase activity [GO:0050048]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; aspartate biosynthetic process [GO:0006532]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]; leucine biosynthetic process [GO:0009098]; tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate [GO:0019292]	transsulfuration [GO:0019346]	aspartate biosynthetic process [GO:0006532]; leucine biosynthetic process [GO:0009098]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]; tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate [GO:0019292]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]	aromatic-amino-acid:2-oxoglutarate aminotransferase activity [GO:0008793]; identical protein binding [GO:0042802]; L-leucine:2-oxoglutarate aminotransferase activity [GO:0050048]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1pgfb1_d5coxd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1pgga1_d1mk8a___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1pggb1_d5coxc1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1pgl22_d1pgw21__1					host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	transport of virus in host, cell to cell [GO:0046740]	transport of virus in host, cell to cell [GO:0046740]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1pgl22_d4q4w1___1					host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	transport of virus in host, cell to cell [GO:0046740]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1pgoa2_d1px0b___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]		D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]		NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]	
d1pgta2_d2vcvd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d1pgtb1_d1guhb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1pgtb2_d1hnaa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]
d1pgtb2_d3c71a___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]
d1pgva__d1fqvc2__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	cytoplasm [GO:0005737]; myofibril [GO:0030016]; striated muscle thin filament [GO:0005865]; terminal web [GO:1990357]; actin filament binding [GO:0051015]; tropomyosin binding [GO:0005523]; embryo development ending in birth or egg hatching [GO:0009792]; locomotion [GO:0040011]; muscle thin filament assembly [GO:0071689]; myofibril assembly [GO:0030239]; negative regulation of actin filament depolymerization [GO:0030835]; nematode larval development [GO:0002119]; pointed-end actin filament capping [GO:0051694]; sarcomere organization [GO:0045214]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	embryo development ending in birth or egg hatching [GO:0009792]; locomotion [GO:0040011]; muscle thin filament assembly [GO:0071689]; myofibril assembly [GO:0030239]; negative regulation of actin filament depolymerization [GO:0030835]; nematode larval development [GO:0002119]; pointed-end actin filament capping [GO:0051694]; sarcomere organization [GO:0045214]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; myofibril [GO:0030016]; striated muscle thin filament [GO:0005865]; terminal web [GO:1990357]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	actin filament binding [GO:0051015]; tropomyosin binding [GO:0005523]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]
d1pgw21_d1ruh.1__1					host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	transport of virus in host, cell to cell [GO:0046740]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1pgw22_d5fmol1__1					host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	transport of virus in host, cell to cell [GO:0046740]	transport of virus in host, cell to cell [GO:0046740]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1pgza2_d4z2xa___1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	commitment complex [GO:0000243]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; spliceosomal complex [GO:0005681]; U2-type prespliceosome [GO:0071004]; U2AF [GO:0089701]; C2H2 zinc finger domain binding [GO:0070742]; enzyme binding [GO:0019899]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA 3'-splice site binding [GO:0030628]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of RNA splicing [GO:0033120]; RNA splicing [GO:0008380]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of RNA splicing [GO:0033120]; RNA splicing [GO:0008380]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	commitment complex [GO:0000243]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; spliceosomal complex [GO:0005681]; U2AF [GO:0089701]; U2-type prespliceosome [GO:0071004]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	C2H2 zinc finger domain binding [GO:0070742]; enzyme binding [GO:0019899]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA 3'-splice site binding [GO:0030628]
d1ph0a__d1xxva1__1	Metazoa		Chordata	Proteobacteria	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	pathogenesis [GO:0009405]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	extracellular region [GO:0005576]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	protein tyrosine phosphatase activity [GO:0004725]
d1ph1a1_d1eqqd___1			Ciliophora	Proteobacteria	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	cytosol [GO:0005829]; enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]	telomere capping [GO:0016233]	DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	cytosol [GO:0005829]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]
d1ph3a2_d1ph7a1__1			Ciliophora	Ciliophora	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	telomere capping [GO:0016233]	telomere capping [GO:0016233]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1ph3a3_d1ph5a1__1			Ciliophora	Ciliophora	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	telomere capping [GO:0016233]	telomere capping [GO:0016233]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1ph3b__d1quqd___1		Metazoa	Ciliophora	Chordata	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; single-stranded DNA binding [GO:0003697]; base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	telomere capping [GO:0016233]	base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	damaged DNA binding [GO:0003684]; single-stranded DNA binding [GO:0003697]
d1ph6b__d2b8kg1__1		Fungi	Ciliophora	Ascomycota	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	telomere capping [GO:0016233]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]
d1ph7a2_d2uuaq1__1			Ciliophora	Deinococcus-Thermus	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	telomere capping [GO:0016233]	translation [GO:0006412]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	ribosome [GO:0005840]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1ph7b__d4dpgf1__1		Metazoa	Ciliophora	Chordata	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]; activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	telomere capping [GO:0016233]	activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]
d1ph8a2_d1ph5a3__1			Ciliophora	Ciliophora	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	telomere capping [GO:0016233]	telomere capping [GO:0016233]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1ph8b__d1il2a1__1			Ciliophora	Proteobacteria	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	telomere capping [GO:0016233]	aspartyl-tRNA aminoacylation [GO:0006422]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	cytosol [GO:0005829]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]
d1ph9a3_d1kxla___1		Fungi	Ciliophora	Ascomycota	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	CST complex [GO:1990879]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; single-stranded telomeric DNA binding [GO:0043047]; telomerase inhibitor activity [GO:0010521]; cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of telomerase activity [GO:0051974]; regulation of telomere maintenance via telomerase [GO:0032210]; ribonucleoprotein complex localization [GO:0071166]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]	telomere capping [GO:0016233]	cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of telomerase activity [GO:0051974]; regulation of telomere maintenance via telomerase [GO:0032210]; ribonucleoprotein complex localization [GO:0071166]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	CST complex [GO:1990879]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; single-stranded telomeric DNA binding [GO:0043047]; telomerase inhibitor activity [GO:0010521]
d1ph9a3_d2i2ul1__1			Ciliophora		nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]		telomere capping [GO:0016233]		nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]		protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	
d1phba__d5cjea___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1phea__d2xbka___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1phha2_d2bk5a2__1		Metazoa	Proteobacteria	Chordata	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1phja1_d1otca1__1			Ciliophora	Ciliophora	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	telomere capping [GO:0016233]	telomere capping [GO:0016233]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1phna__d2dfoa___1			Rhodophyta		chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]			
d1phna__d2uumm___1			Rhodophyta	Cyanobacteria	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	phycobilisome [GO:0030089]		
d1phsa1_d1caxb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	aleurone grain [GO:0033095]; vacuole [GO:0005773]; nutrient reservoir activity [GO:0045735]	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]		protein homotrimerization [GO:0070207]	aleurone grain [GO:0033095]; vacuole [GO:0005773]	protein-containing complex [GO:0032991]	nutrient reservoir activity [GO:0045735]	identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]
d1phsa1_d3njza___1	Viridiplantae		Streptophyta	Proteobacteria	aleurone grain [GO:0033095]; vacuole [GO:0005773]; nutrient reservoir activity [GO:0045735]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]			aleurone grain [GO:0033095]; vacuole [GO:0005773]		nutrient reservoir activity [GO:0045735]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1pifa1_d2cpua1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate catabolic process [GO:0016052]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1pifa2_d1jyzj5__1	Metazoa		Chordata		extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]		carbohydrate catabolic process [GO:0016052]		extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	
d1pifa2_d4gqqa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate catabolic process [GO:0016052]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1piga1_d1xh0a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate catabolic process [GO:0016052]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1pimb__d4toer___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1pina2_d2l2sa1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	metal ion binding [GO:0046872]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]		beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	metal ion binding [GO:0046872]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1piua__d3a68l___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1piub__d4dasm___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1piwa2_d4nbta___1	Fungi		Ascomycota	Tenericutes	alcohol dehydrogenase (NADP+) activity [GO:0008106]; hydroxymethylfurfural reductase (NADH) activity [GO:0033833]; hydroxymethylfurfural reductase (NADPH) activity [GO:0033845]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; zinc ion binding [GO:0008270]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; furaldehyde metabolic process [GO:0033859]	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; nucleotide binding [GO:0000166]	alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; furaldehyde metabolic process [GO:0033859]				alcohol dehydrogenase (NADP+) activity [GO:0008106]; hydroxymethylfurfural reductase (NADH) activity [GO:0033833]; hydroxymethylfurfural reductase (NADPH) activity [GO:0033845]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; zinc ion binding [GO:0008270]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; nucleotide binding [GO:0000166]
d1piwb2_d2aa3c1__1	Fungi		Ascomycota	Apicomplexa	alcohol dehydrogenase (NADP+) activity [GO:0008106]; hydroxymethylfurfural reductase (NADH) activity [GO:0033833]; hydroxymethylfurfural reductase (NADPH) activity [GO:0033845]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; zinc ion binding [GO:0008270]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; furaldehyde metabolic process [GO:0033859]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; furaldehyde metabolic process [GO:0033859]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]			alcohol dehydrogenase (NADP+) activity [GO:0008106]; hydroxymethylfurfural reductase (NADH) activity [GO:0033833]; hydroxymethylfurfural reductase (NADPH) activity [GO:0033845]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; zinc ion binding [GO:0008270]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d1pixa3_d2zl2j___1			Firmicutes	Proteobacteria	carboxy-lyase activity [GO:0016831]; decarboxylation-driven active transmembrane transporter activity [GO:0015451]; ligase activity [GO:0016874]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; sodium ion transport [GO:0006814]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; sodium ion transport [GO:0006814]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	carboxy-lyase activity [GO:0016831]; decarboxylation-driven active transmembrane transporter activity [GO:0015451]; ligase activity [GO:0016874]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d1piyb__d1jrek___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1pj1a__d4m1hb1__1			Proteobacteria	Chlamydiae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ribonucleoside-diphosphate reductase complex [GO:0005971]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1pj5a3_d1oj9b2__1		Metazoa	Actinobacteria	Chordata	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d1pj6a3_d2xasa3__1		Metazoa	Actinobacteria	Chordata	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]		blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]		DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1pj6a3_d3qsma2__1			Actinobacteria	Firmicutes	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]		tetrahydrofolate metabolic process [GO:0046653]		cytoplasm [GO:0005737]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	sarcosine oxidase activity [GO:0008115]
d1pj6a4_d3a8id1__1			Actinobacteria	Proteobacteria	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]; lipoic acid binding [GO:0031405]; glycine decarboxylation via glycine cleavage system [GO:0019464]		glycine decarboxylation via glycine cleavage system [GO:0019464]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	lipoic acid binding [GO:0031405]
d1pj7a3_d2gb0a2__1			Actinobacteria	Firmicutes	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]		tetrahydrofolate metabolic process [GO:0046653]		cytoplasm [GO:0005737]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	sarcosine oxidase activity [GO:0008115]
d1pj8a__d1ke1a___1	Fungi		Ascomycota		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]						metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	
d1pj9a1_d2bp3b___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; thrombin-activated receptor activity [GO:0015057]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	carbohydrate metabolic process [GO:0005975]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	extracellular region [GO:0005576]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	thrombin-activated receptor activity [GO:0015057]
d1pjia1_d1k3wa1__1			Firmicutes	Proteobacteria	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA N-glycosylase activity [GO:0019104]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [GO:0000703]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]			class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA N-glycosylase activity [GO:0019104]; endonuclease activity [GO:0004519]; oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [GO:0000703]; zinc ion binding [GO:0008270]
d1pjja1_d4g4na2__1			Firmicutes	Firmicutes	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]			class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]
d1pjja2_d4g4qa1__1			Firmicutes	Firmicutes	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]			class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]
d1pjmb__d1o6pb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; enzyme binding [GO:0019899]; Hsp90 protein binding [GO:0051879]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein domain specific binding [GO:0019904]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; apoptotic DNA fragmentation [GO:0006309]; astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; intracellular transport of virus [GO:0075733]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; modulation by virus of host cellular process [GO:0019054]; neutrophil degranulation [GO:0043312]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal protein import into nucleus [GO:0006610]	entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	apoptotic DNA fragmentation [GO:0006309]; astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; intracellular transport of virus [GO:0075733]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; modulation by virus of host cellular process [GO:0019054]; neutrophil degranulation [GO:0043312]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal protein import into nucleus [GO:0006610]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]	enzyme binding [GO:0019899]; Hsp90 protein binding [GO:0051879]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein domain specific binding [GO:0019904]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1pjqb1_d3r1ia___1			Proteobacteria	Actinobacteria	NAD binding [GO:0051287]; precorrin-2 dehydrogenase activity [GO:0043115]; sirohydrochlorin ferrochelatase activity [GO:0051266]; uroporphyrin-III C-methyltransferase activity [GO:0004851]; cobalamin biosynthetic process [GO:0009236]; siroheme biosynthetic process [GO:0019354]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	cobalamin biosynthetic process [GO:0009236]; siroheme biosynthetic process [GO:0019354]				NAD binding [GO:0051287]; precorrin-2 dehydrogenase activity [GO:0043115]; sirohydrochlorin ferrochelatase activity [GO:0051266]; uroporphyrin-III C-methyltransferase activity [GO:0004851]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d1pjtb1_d1ju9a2__1		Metazoa	Proteobacteria	Chordata	NAD binding [GO:0051287]; precorrin-2 dehydrogenase activity [GO:0043115]; sirohydrochlorin ferrochelatase activity [GO:0051266]; uroporphyrin-III C-methyltransferase activity [GO:0004851]; cobalamin biosynthetic process [GO:0009236]; siroheme biosynthetic process [GO:0019354]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cobalamin biosynthetic process [GO:0009236]; siroheme biosynthetic process [GO:0019354]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	NAD binding [GO:0051287]; precorrin-2 dehydrogenase activity [GO:0043115]; sirohydrochlorin ferrochelatase activity [GO:0051266]; uroporphyrin-III C-methyltransferase activity [GO:0004851]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1pjwa__d1qfha1__1					host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]; actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]; actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]
d1pjza__d4x7ua___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; thiopurine S-methyltransferase activity [GO:0008119]; response to metal ion [GO:0010038]; response to tellurium ion [GO:0046690]	magnesium ion binding [GO:0000287]; O-methyltransferase activity [GO:0008171]; antibiotic biosynthetic process [GO:0017000]; methylation [GO:0032259]	response to metal ion [GO:0010038]; response to tellurium ion [GO:0046690]	antibiotic biosynthetic process [GO:0017000]; methylation [GO:0032259]	cytoplasm [GO:0005737]		thiopurine S-methyltransferase activity [GO:0008119]	magnesium ion binding [GO:0000287]; O-methyltransferase activity [GO:0008171]
d1pk0e__d3rlzb___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1pk0f__d1irjh___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1pk3c2_d3seib1__1	Metazoa	Metazoa	Arthropoda	Chordata	nucleus [GO:0005634]; polytene chromosome [GO:0005700]; PRC1 complex [GO:0035102]; identical protein binding [GO:0042802]; PRC1 complex binding [GO:0140259]; zinc ion binding [GO:0008270]; axonogenesis [GO:0007409]; chromatin organization [GO:0006325]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; ventral cord development [GO:0007419]	cytoplasm [GO:0005737]; membrane [GO:0016020]; identical protein binding [GO:0042802]; signal transduction [GO:0007165]	axonogenesis [GO:0007409]; chromatin organization [GO:0006325]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; ventral cord development [GO:0007419]	signal transduction [GO:0007165]	nucleus [GO:0005634]; polytene chromosome [GO:0005700]; PRC1 complex [GO:0035102]	cytoplasm [GO:0005737]; membrane [GO:0016020]	identical protein binding [GO:0042802]; PRC1 complex binding [GO:0140259]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]
d1pk7b__d3lgsa___1		Viridiplantae	Proteobacteria	Streptophyta	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	purine nucleoside metabolic process [GO:0042278]	L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]		cytosol [GO:0005829]; plasma membrane [GO:0005886]	purine-nucleoside phosphorylase activity [GO:0004731]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d1pk9a__d1otyb___1			Proteobacteria	Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	purine nucleoside metabolic process [GO:0042278]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]		cytosol [GO:0005829]; membrane [GO:0016020]	purine-nucleoside phosphorylase activity [GO:0004731]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]
d1pk9b__d3nbqb___1		Metazoa	Proteobacteria	Chordata	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uridine phosphorylase activity [GO:0004850]; cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	purine nucleoside metabolic process [GO:0042278]	cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]	purine-nucleoside phosphorylase activity [GO:0004731]	uridine phosphorylase activity [GO:0004850]
d1pkdb1_d1aisb1__1	Metazoa		Chordata	Euryarchaeota	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA-templated transcription, initiation [GO:0006352]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]		ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1pkdd1_d5efqb2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cyclin K-CDK12 complex [GO:0002944]; cyclin K-CDK13 complex [GO:0002945]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cell cycle arrest [GO:0071157]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues [GO:2001165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cell cycle arrest [GO:0071157]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues [GO:2001165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin K-CDK12 complex [GO:0002944]; cyclin K-CDK13 complex [GO:0002945]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]
d1pkhb__d4a6ak___1			Euryarchaeota	Actinobacteria	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]			dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d1pkjb__d4oopa___1		Viridiplantae	Euryarchaeota	Streptophyta	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	cytosol [GO:0005829]; dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]		cytosol [GO:0005829]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1pkka__d1f7nb___1			Euryarchaeota		dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]			dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d1pkka__d2pc5a___1		Viridiplantae	Euryarchaeota	Streptophyta	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	cytosol [GO:0005829]; dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]		cytosol [GO:0005829]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1pkle1_d2vgfa1__1		Metazoa		Chordata	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]		ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1pkma3_d2g50c3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; positive regulation of sprouting angiogenesis [GO:1903672]	positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d1pkqa2_d1eeub___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	signaling receptor binding [GO:0005102]	antigen binding [GO:0003823]
d1pkqb1_d1g7hb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	signaling receptor binding [GO:0005102]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1pkqb2_d3k1kc1__1	Metazoa	Metazoa	Chordata	Cnidaria	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]	aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]		signaling receptor binding [GO:0005102]	
d1pkqe1_d3lkra2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	signaling receptor binding [GO:0005102]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1pkqf1_d1dqta___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]	signaling receptor binding [GO:0005102]	
d1pkqf1_d3cfkj2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	signaling receptor binding [GO:0005102]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1pkqj1_d2rhea___1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]		aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]		signaling receptor binding [GO:0005102]	
d1pkuc2_d1vyak___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]
d1pkud2_d1s57e___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]		chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1pkue2_d1w7wd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d1pkug2_d2hvda___1	Viridiplantae	Metazoa	Streptophyta	Chordata	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]; cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]		cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]
d1pkuh2_d3q89f___1	Viridiplantae		Streptophyta	Firmicutes	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1pkuj2_d3ztoa___1	Viridiplantae		Streptophyta	Aquificae	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1pkuk2_d3ee3b1__1	Viridiplantae		Streptophyta		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1pkva__d2qdxa1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; riboflavin synthase activity [GO:0004746]; riboflavin biosynthetic process [GO:0009231]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]; cellular response to oxidative stress [GO:0034599]; heme catabolic process [GO:0042167]	riboflavin biosynthetic process [GO:0009231]	cellular response to oxidative stress [GO:0034599]; heme catabolic process [GO:0042167]	cytosol [GO:0005829]		riboflavin synthase activity [GO:0004746]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1pkwb2_d4acsb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d1pkxb1_d2iu0b1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1pkxd1_d1ce8c2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1pkzb2_d4llrd___1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1pl0a1_d2b1gc1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1pl0b1_d1jdbe2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1pl0b1_d1oz0b1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1pl0c1_d1keeg2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1pl0d1_d1wo8b___1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]		cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	methylglyoxal synthase activity [GO:0008929]
d1pl1a2_d1ev4d2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]; aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]
d1pl1a2_d3tkqe___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d1pl3b__d4qi3b1__1	Fungi	Fungi	Basidiomycota	Ascomycota	extracellular region [GO:0005576]; cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]	cellulose binding [GO:0030248]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]
d1pl4a1_d1qnnc1__1	Metazoa		Chordata	Bacteroidetes	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1pl4b2_d4gunp2__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1pl4c1_d3h1sb1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1pl4d1_d4guna1__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1pl4d2_d2cdya2__1	Metazoa		Chordata	Deinococcus-Thermus	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1pl4d2_d4x9qc2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	removal of superoxide radicals [GO:0019430]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]
d1pl7a2_d1ht0b2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; motile cilium [GO:0031514]; (R,R)-butanediol dehydrogenase activity [GO:0000721]; carbohydrate binding [GO:0030246]; D-xylulose reductase activity [GO:0046526]; identical protein binding [GO:0042802]; L-iditol 2-dehydrogenase activity [GO:0003939]; NAD binding [GO:0051287]; ribitol 2-dehydrogenase activity [GO:0050255]; zinc ion binding [GO:0008270]; flagellated sperm motility [GO:0030317]; fructose biosynthetic process [GO:0046370]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; L-xylitol catabolic process [GO:0051160]; L-xylitol metabolic process [GO:0051164]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; sorbitol catabolic process [GO:0006062]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	flagellated sperm motility [GO:0030317]; fructose biosynthetic process [GO:0046370]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; L-xylitol catabolic process [GO:0051160]; L-xylitol metabolic process [GO:0051164]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; sorbitol catabolic process [GO:0006062]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; motile cilium [GO:0031514]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	(R,R)-butanediol dehydrogenase activity [GO:0000721]; carbohydrate binding [GO:0030246]; D-xylulose reductase activity [GO:0046526]; identical protein binding [GO:0042802]; L-iditol 2-dehydrogenase activity [GO:0003939]; NAD binding [GO:0051287]; ribitol 2-dehydrogenase activity [GO:0050255]; zinc ion binding [GO:0008270]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1pl7a2_d1zmoc___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; motile cilium [GO:0031514]; (R,R)-butanediol dehydrogenase activity [GO:0000721]; carbohydrate binding [GO:0030246]; D-xylulose reductase activity [GO:0046526]; identical protein binding [GO:0042802]; L-iditol 2-dehydrogenase activity [GO:0003939]; NAD binding [GO:0051287]; ribitol 2-dehydrogenase activity [GO:0050255]; zinc ion binding [GO:0008270]; flagellated sperm motility [GO:0030317]; fructose biosynthetic process [GO:0046370]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; L-xylitol catabolic process [GO:0051160]; L-xylitol metabolic process [GO:0051164]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; sorbitol catabolic process [GO:0006062]		flagellated sperm motility [GO:0030317]; fructose biosynthetic process [GO:0046370]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; L-xylitol catabolic process [GO:0051160]; L-xylitol metabolic process [GO:0051164]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; sorbitol catabolic process [GO:0006062]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; motile cilium [GO:0031514]		(R,R)-butanediol dehydrogenase activity [GO:0000721]; carbohydrate binding [GO:0030246]; D-xylulose reductase activity [GO:0046526]; identical protein binding [GO:0042802]; L-iditol 2-dehydrogenase activity [GO:0003939]; NAD binding [GO:0051287]; ribitol 2-dehydrogenase activity [GO:0050255]; zinc ion binding [GO:0008270]	
d1pl7d2_d3pjfb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; motile cilium [GO:0031514]; (R,R)-butanediol dehydrogenase activity [GO:0000721]; carbohydrate binding [GO:0030246]; D-xylulose reductase activity [GO:0046526]; identical protein binding [GO:0042802]; L-iditol 2-dehydrogenase activity [GO:0003939]; NAD binding [GO:0051287]; ribitol 2-dehydrogenase activity [GO:0050255]; zinc ion binding [GO:0008270]; flagellated sperm motility [GO:0030317]; fructose biosynthetic process [GO:0046370]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; L-xylitol catabolic process [GO:0051160]; L-xylitol metabolic process [GO:0051164]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; sorbitol catabolic process [GO:0006062]	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	flagellated sperm motility [GO:0030317]; fructose biosynthetic process [GO:0046370]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; L-xylitol catabolic process [GO:0051160]; L-xylitol metabolic process [GO:0051164]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; sorbitol catabolic process [GO:0006062]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; motile cilium [GO:0031514]	cytosol [GO:0005829]; membrane [GO:0016020]	(R,R)-butanediol dehydrogenase activity [GO:0000721]; carbohydrate binding [GO:0030246]; D-xylulose reductase activity [GO:0046526]; identical protein binding [GO:0042802]; L-iditol 2-dehydrogenase activity [GO:0003939]; NAD binding [GO:0051287]; ribitol 2-dehydrogenase activity [GO:0050255]; zinc ion binding [GO:0008270]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]
d1pl8a2_d1hwya1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; motile cilium [GO:0031514]; (R,R)-butanediol dehydrogenase activity [GO:0000721]; carbohydrate binding [GO:0030246]; D-xylulose reductase activity [GO:0046526]; identical protein binding [GO:0042802]; L-iditol 2-dehydrogenase activity [GO:0003939]; NAD binding [GO:0051287]; ribitol 2-dehydrogenase activity [GO:0050255]; zinc ion binding [GO:0008270]; flagellated sperm motility [GO:0030317]; fructose biosynthetic process [GO:0046370]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; L-xylitol catabolic process [GO:0051160]; L-xylitol metabolic process [GO:0051164]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; sorbitol catabolic process [GO:0006062]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	flagellated sperm motility [GO:0030317]; fructose biosynthetic process [GO:0046370]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; L-xylitol catabolic process [GO:0051160]; L-xylitol metabolic process [GO:0051164]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; sorbitol catabolic process [GO:0006062]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; motile cilium [GO:0031514]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	(R,R)-butanediol dehydrogenase activity [GO:0000721]; carbohydrate binding [GO:0030246]; D-xylulose reductase activity [GO:0046526]; identical protein binding [GO:0042802]; L-iditol 2-dehydrogenase activity [GO:0003939]; NAD binding [GO:0051287]; ribitol 2-dehydrogenase activity [GO:0050255]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1plba__d1id2a___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			chloroplast thylakoid membrane [GO:0009535]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1plba__d3t6wc1__1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]			chloroplast thylakoid membrane [GO:0009535]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1plca__d1ilua___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane [GO:0009535]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1plca__d1npja2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	chloroplast thylakoid membrane [GO:0009535]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1plgl1_d1k6ql1__1	Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d1plgl1_d3gkza1__1	Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d1plgl2_d2adga1__1	Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d1plqa2_d1b77a2__1	Fungi		Ascomycota		chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	
d1plua__d1ogox2__1		Fungi	Proteobacteria	Ascomycota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; dextranase activity [GO:0033904]; metabolic process [GO:0008152]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	metabolic process [GO:0008152]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	dextranase activity [GO:0033904]
d1pm1x__d2f73g2__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	vasodilation [GO:0042311]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]
d1pm2a__d1fz6a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1pm2a__d1jkub___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]
d1pm2b__d5tdua___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	toluene catabolic process [GO:0042203]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1pm5a2_d1k82c2__1			Firmicutes	Proteobacteria	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA N-glycosylase activity [GO:0019104]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [GO:0000703]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]			class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA N-glycosylase activity [GO:0019104]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [GO:0000703]; zinc ion binding [GO:0008270]
d1pm7b__d1lrhb___1		Viridiplantae	Actinobacteria	Streptophyta	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]	endoplasmic reticulum lumen [GO:0005788]; auxin binding [GO:0010011]; zinc ion binding [GO:0008270]; auxin-activated signaling pathway [GO:0009734]; cytokinesis by cell plate formation [GO:0000911]; positive regulation of cell division [GO:0051781]; positive regulation of cell size [GO:0045793]; positive regulation of DNA endoreduplication [GO:0032877]; unidimensional cell growth [GO:0009826]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]	auxin-activated signaling pathway [GO:0009734]; cytokinesis by cell plate formation [GO:0000911]; positive regulation of cell division [GO:0051781]; positive regulation of cell size [GO:0045793]; positive regulation of DNA endoreduplication [GO:0032877]; unidimensional cell growth [GO:0009826]		endoplasmic reticulum lumen [GO:0005788]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	auxin binding [GO:0010011]; zinc ion binding [GO:0008270]
d1pm9a1_d1xrea1__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	removal of superoxide radicals [GO:0019430]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1pm9a2_d4dvhb2__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1pm9b1_d1abma3__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	
d1pm9b1_d2gojb1__1	Metazoa		Chordata	Apicomplexa	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1pmac__d4z1lh___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1pmag__d4qvnq___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1pmah__d1k7d.1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	periplasmic space [GO:0042597]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]
d1pmah__d5cz6b___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1pmai__d5fhss___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1pmak__d4g4sg___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1pmam__d4qz1c___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1pmam__d5d0vf___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1pmar__d3unfg___1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	proteasomal protein catabolic process [GO:0010498]	antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1pmas__d4jsqx___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1pmat__d5l5hn___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1pmax__d5l64j___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1pmbb__d1mtja___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1pmbb__d2uunq___1	Metazoa		Chordata		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1pmjx__d2bq9a3__1			Firmicutes		carbohydrate binding [GO:0030246]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]; substituted mannan metabolic process [GO:0006080]		substituted mannan metabolic process [GO:0006080]				carbohydrate binding [GO:0030246]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]	
d1pmoa__d5xmpa___1			Proteobacteria	Apicomplexa	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d1pmob__d1ahxb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1pmof__d2vgsa___1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]
d1pmpc__d2f73h2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; myelin sheath [GO:0043209]; cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]; membrane organization [GO:0061024]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	membrane organization [GO:0061024]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	cytoplasm [GO:0005737]; myelin sheath [GO:0043209]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]
d1pmta2_d3csia2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1pmzb__d1uhib___1		Metazoa		Cnidaria		calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]		bioluminescence [GO:0008218]				calcium ion binding [GO:0005509]
d1pmzc__d1k9ub___1		Viridiplantae		Streptophyta		calcium ion binding [GO:0005509]						calcium ion binding [GO:0005509]
d1pn0b2_d1uc7a___1	Fungi		Basidiomycota	Proteobacteria	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]; phenol-containing compound catabolic process [GO:0019336]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	phenol-containing compound catabolic process [GO:0019336]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]		cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]	electron transfer activity [GO:0009055]; protein-disulfide reductase activity [GO:0047134]
d1pn0c2_d2vl2c___1	Fungi	Metazoa	Basidiomycota	Chordata	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]; phenol-containing compound catabolic process [GO:0019336]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	phenol-containing compound catabolic process [GO:0019336]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]
d1pn0c2_d4mjba___1	Fungi		Basidiomycota	Cyanobacteria	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]; phenol-containing compound catabolic process [GO:0019336]	cell [GO:0005623]; electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	phenol-containing compound catabolic process [GO:0019336]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]		cell [GO:0005623]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]	electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]
d1pn4a2_d2egif___1	Fungi		Ascomycota	Aquificae	peroxisome [GO:0005777]; isomerase activity [GO:0016853]; lyase activity [GO:0016829]; oxidoreductase activity [GO:0016491]; fatty acid beta-oxidation [GO:0006635]	acyl-CoA hydrolase activity [GO:0047617]	fatty acid beta-oxidation [GO:0006635]		peroxisome [GO:0005777]		isomerase activity [GO:0016853]; lyase activity [GO:0016829]; oxidoreductase activity [GO:0016491]	acyl-CoA hydrolase activity [GO:0047617]
d1pn9a1_d4ivff2__1	Metazoa	Fungi	Arthropoda	Ascomycota	cytoplasm [GO:0005737]; DDT-dehydrochlorinase activity [GO:0018833]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]		glutathione metabolic process [GO:0006749]		cytoplasm [GO:0005737]		DDT-dehydrochlorinase activity [GO:0018833]; glutathione transferase activity [GO:0004364]	
d1pnda__d4f05b2__1	Viridiplantae		Streptophyta		chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				chloroplast thylakoid membrane [GO:0009535]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	
d1pnga2_d1pgsa2__1			Bacteroidetes	Bacteroidetes	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]					oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]
d1pnra2_d4gpaa___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]; negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of synapse structure or activity [GO:0050803]; response to fungicide [GO:0060992]; synaptic transmission, glutamatergic [GO:0035249]	negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]	chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of synapse structure or activity [GO:0050803]; response to fungicide [GO:0060992]; synaptic transmission, glutamatergic [GO:0035249]	cytosol [GO:0005829]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; terminal bouton [GO:0043195]	DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]	AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1po13__d1pvc3___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1po21__d4rqpo___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1po23__d1yc6z___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1po23__d2rmu3___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1po7a1_d1v5ea1__1			Proteobacteria	Firmicutes	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d1po7a2_d3exg41__1		Metazoa	Proteobacteria	Chordata	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	mandelate catabolic process [GO:0019596]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1po7a3_d4c7xa2__1			Proteobacteria	Firmicutes	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1po8a__d3hzwb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]
d1poba__d1y75b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]
d1poid__d2nrcd1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; glutaconate CoA-transferase activity [GO:0018730]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	cytoplasm [GO:0005737]	mitochondrion [GO:0005739]	glutaconate CoA-transferase activity [GO:0018730]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]
d1pooa__d1cvma___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; 3-phytase activity [GO:0016158]	extracellular region [GO:0005576]; 3-phytase activity [GO:0016158]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	3-phytase activity [GO:0016158]	3-phytase activity [GO:0016158]
d1popa__d2avwd___1	Viridiplantae		Streptophyta	Firmicutes	cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]					cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]
d1pota__d5l9sa___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; putrescine binding [GO:0019810]; spermidine binding [GO:0019809]; putrescine transport [GO:0015847]; spermidine transport [GO:0015848]	integral component of membrane [GO:0016021]	putrescine transport [GO:0015847]; spermidine transport [GO:0015848]		outer membrane-bounded periplasmic space [GO:0030288]	integral component of membrane [GO:0016021]	putrescine binding [GO:0019810]; spermidine binding [GO:0019809]	
d1pov1__d1e57b___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1powa1_d2wvha2__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1powb2_d1poxb2__1			Firmicutes	Firmicutes	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d1poxa1_d1mczc1__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1poxa1_d2vk1a2__1		Fungi	Firmicutes	Ascomycota	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1poxa3_d1itzb1__1		Viridiplantae	Firmicutes	Streptophyta	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]		pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]
d1poxb3_d2bp7h1__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]					magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]
d1poy1__d4n4ua1__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; putrescine binding [GO:0019810]; spermidine binding [GO:0019809]; putrescine transport [GO:0015847]; spermidine transport [GO:0015848]	transmembrane transport [GO:0055085]	putrescine transport [GO:0015847]; spermidine transport [GO:0015848]	transmembrane transport [GO:0055085]	outer membrane-bounded periplasmic space [GO:0030288]		putrescine binding [GO:0019810]; spermidine binding [GO:0019809]	
d1poy4__d2yjpb___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; putrescine binding [GO:0019810]; spermidine binding [GO:0019809]; putrescine transport [GO:0015847]; spermidine transport [GO:0015848]	metal ion binding [GO:0046872]	putrescine transport [GO:0015847]; spermidine transport [GO:0015848]		outer membrane-bounded periplasmic space [GO:0030288]		putrescine binding [GO:0019810]; spermidine binding [GO:0019809]	metal ion binding [GO:0046872]
d1pp4a__d1vyhq1__1	Fungi	Metazoa	Ascomycota	Chordata	hydrolase activity [GO:0016787]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; 1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; platelet-activating factor acetyltransferase activity [GO:0047179]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; brain development [GO:0007420]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; neutrophil degranulation [GO:0043312]; positive regulation of macroautophagy [GO:0016239]; spermatogenesis [GO:0007283]		brain development [GO:0007420]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; neutrophil degranulation [GO:0043312]; positive regulation of macroautophagy [GO:0016239]; spermatogenesis [GO:0007283]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	hydrolase activity [GO:0016787]	1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; platelet-activating factor acetyltransferase activity [GO:0047179]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d1pp8u__d4a2uc2__1				Actinobacteria	metal ion binding [GO:0046872]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]		negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1pp9a2_d3l70a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1pp9b2_d3l71b1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1pp9e1_d3l72r2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1pp9e1_d4hm7a1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	aromatic compound catabolic process [GO:0019439]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]
d1pp9n1_d3bcca2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1pp9q1_d3l73d1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1pp9r1_d1z01f1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d1pphe__d1ssxa___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d1ppia2_d3gxfb2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate catabolic process [GO:0016052]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular space [GO:0005615]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1ppja1_d1hr9c1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]; aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]
d1ppja2_d2fqta___1	Metazoa		Chordata	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]; quorum sensing [GO:0009372]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	quorum sensing [GO:0009372]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]
d1ppjb2_d3l70b1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1ppjd1_d5cifb___1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1ppjr1_d2b24e1__1	Metazoa		Chordata	Actinobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cellular metabolic process [GO:0044237]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]
d1ppke__d1w5xa___1	Fungi		Ascomycota		extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ppke__d2rmpa___1	Fungi	Fungi	Ascomycota	Mucoromycota	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]			extracellular region [GO:0005576]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1pple__d2qzxb___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	extracellular region [GO:0005576]; fungal biofilm matrix [GO:0062040]; fungal-type cell wall [GO:0009277]; aspartic-type endopeptidase activity [GO:0004190]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]		fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; fungal biofilm matrix [GO:0062040]; fungal-type cell wall [GO:0009277]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1ppro1_d1ppro2__1					chloroplast [GO:0009507]; light-harvesting complex [GO:0030076]; chlorophyll binding [GO:0016168]; protein-chromophore linkage [GO:0018298]	chloroplast [GO:0009507]; light-harvesting complex [GO:0030076]; chlorophyll binding [GO:0016168]; protein-chromophore linkage [GO:0018298]	protein-chromophore linkage [GO:0018298]	protein-chromophore linkage [GO:0018298]	chloroplast [GO:0009507]; light-harvesting complex [GO:0030076]	chloroplast [GO:0009507]; light-harvesting complex [GO:0030076]	chlorophyll binding [GO:0016168]	chlorophyll binding [GO:0016168]
d1ppwa__d1tuma___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]		hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]
d1pq3b__d1r1oa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1pq3c__d2rlaa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1pq5a__d1afq.1__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]		digestion [GO:0007586]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1pq5a__d4ghta1__1	Fungi		Ascomycota		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1pq7a__d1vcwb2__1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]		cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]	serine-type endopeptidase activity [GO:0004252]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1pqea__d1e61c1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aspartate 1-decarboxylase activity [GO:0004068]; alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]		cytosol [GO:0005829]	periplasmic space [GO:0042597]	aspartate 1-decarboxylase activity [GO:0004068]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]
d1pqkb__d2dqiy___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1pqkc__d4ddca___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1pqoa__d1bb6a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	host cell cytoplasm [GO:0030430]	extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1pqpa2_d1i32b2__1			Proteobacteria		aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		glycosome [GO:0020015]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1pqud2_d1i33a2__1			Proteobacteria		aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		glycosome [GO:0020015]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1pqza2_d3o6fa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1pr3a2_d4r5hb2__1			Proteobacteria		aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]		'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]				aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	
d1pr9a__d4kuhb1__1	Metazoa		Chordata	Firmicutes	brush border [GO:0005903]; cytoplasmic microtubule [GO:0005881]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NAD+) activity [GO:0044105]; L-xylulose reductase (NADP+) activity [GO:0050038]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	fatty acid metabolic process [GO:0006631]	brush border [GO:0005903]; cytoplasmic microtubule [GO:0005881]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NAD+) activity [GO:0044105]; L-xylulose reductase (NADP+) activity [GO:0050038]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]
d1pr9b__d5x8hb___1	Metazoa		Chordata	Bacteroidetes	brush border [GO:0005903]; cytoplasmic microtubule [GO:0005881]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NAD+) activity [GO:0044105]; L-xylulose reductase (NADP+) activity [GO:0050038]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	oxidoreductase activity [GO:0016491]	D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]		brush border [GO:0005903]; cytoplasmic microtubule [GO:0005881]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NAD+) activity [GO:0044105]; L-xylulose reductase (NADP+) activity [GO:0050038]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]	oxidoreductase activity [GO:0016491]
d1prch1_d2hh1h2__1			Proteobacteria	Proteobacteria	plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	integral component of membrane [GO:0016021]; plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	integral component of membrane [GO:0016021]; plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]
d1prea1_d1ptoi2__1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]			extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	identical protein binding [GO:0042802]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1preb1_d1prti2__1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]			extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	identical protein binding [GO:0042802]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1prga__d4wqpa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]; activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d1prha1_d1gwoa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	extracellular region [GO:0005576]; vacuole [GO:0005773]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1prha1_d3n8za2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1prhb1_d1pxxa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1prob__d2aoca___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1prra1_d4fd9a___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; sporulation resulting in formation of a cellular spore [GO:0030435]	protein-containing complex [GO:0032991]; carbohydrate binding [GO:0030246]; protein kinase A binding [GO:0051018]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	sporulation resulting in formation of a cellular spore [GO:0030435]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; protein kinase A binding [GO:0051018]; structural constituent of eye lens [GO:0005212]
d1prsa1_d1ziea1__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; sporulation resulting in formation of a cellular spore [GO:0030435]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	sporulation resulting in formation of a cellular spore [GO:0030435]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d1prsa2_d3hz2b___1			Proteobacteria	Euryarchaeota	metal ion binding [GO:0046872]; sporulation resulting in formation of a cellular spore [GO:0030435]	metal ion binding [GO:0046872]	sporulation resulting in formation of a cellular spore [GO:0030435]				metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1prtb1_d1cqfd___1			Proteobacteria		extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1prtb1_d1ts2b1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1prth1_d1qb5f___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]			extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1prti2_d4n37b___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]		antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1prtj__d4ulla___1			Proteobacteria		extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1prya__d3evda___1			Euryarchaeota		methyltransferase activity [GO:0008168]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; negative regulation of RNA interference [GO:1900369]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; negative regulation of RNA interference [GO:1900369]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	methyltransferase activity [GO:0008168]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1ps0a2_d1agnb2__1	Fungi	Metazoa	Ascomycota	Chordata	alcohol dehydrogenase (NADP+) activity [GO:0008106]; hydroxymethylfurfural reductase (NADH) activity [GO:0033833]; hydroxymethylfurfural reductase (NADPH) activity [GO:0033845]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; zinc ion binding [GO:0008270]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; furaldehyde metabolic process [GO:0033859]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; furaldehyde metabolic process [GO:0033859]	ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; plasma membrane [GO:0005886]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; hydroxymethylfurfural reductase (NADH) activity [GO:0033833]; hydroxymethylfurfural reductase (NADPH) activity [GO:0033845]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; zinc ion binding [GO:0008270]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1ps0a2_d1t1sa2__1	Fungi		Ascomycota	Proteobacteria	alcohol dehydrogenase (NADP+) activity [GO:0008106]; hydroxymethylfurfural reductase (NADH) activity [GO:0033833]; hydroxymethylfurfural reductase (NADPH) activity [GO:0033845]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; zinc ion binding [GO:0008270]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; furaldehyde metabolic process [GO:0033859]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; furaldehyde metabolic process [GO:0033859]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]			alcohol dehydrogenase (NADP+) activity [GO:0008106]; hydroxymethylfurfural reductase (NADH) activity [GO:0033833]; hydroxymethylfurfural reductase (NADPH) activity [GO:0033845]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; zinc ion binding [GO:0008270]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]
d1ps3a2_d1nssa1__1	Metazoa		Arthropoda	Firmicutes	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	galactose metabolic process [GO:0006012]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1ps4a__d1p7zd1__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]		cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1ps6a__d2qfwf___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; 4-hydroxythreonine-4-phosphate dehydrogenase activity [GO:0050570]; cobalt ion binding [GO:0050897]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; zinc ion binding [GO:0008270]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]	glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	4-hydroxythreonine-4-phosphate dehydrogenase activity [GO:0050570]; cobalt ion binding [GO:0050897]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; zinc ion binding [GO:0008270]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1psaa__d4y3na___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	aspartic-type endopeptidase activity [GO:0004190]	digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		extracellular region [GO:0005576]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1psba__d1xfyt1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1psca__d1ra5a2__1			Proteobacteria	Proteobacteria	plasma membrane [GO:0005886]; aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]; catabolic process [GO:0009056]	cytosol [GO:0005829]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; isoguanine deaminase activity [GO:0035888]; zinc ion binding [GO:0008270]; cytosine catabolic process [GO:0006209]	catabolic process [GO:0009056]	cytosine catabolic process [GO:0006209]	plasma membrane [GO:0005886]	cytosol [GO:0005829]	aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; isoguanine deaminase activity [GO:0035888]; zinc ion binding [GO:0008270]
d1psda3_d3qsie___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	L-serine biosynthetic process [GO:0006564]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	cytosol [GO:0005829]	protein-DNA complex [GO:0032993]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1psdb3_d3dc2b4__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; cellular amino acid metabolic process [GO:0006520]; L-serine biosynthetic process [GO:0006564]	L-serine biosynthetic process [GO:0006564]	cellular amino acid metabolic process [GO:0006520]; L-serine biosynthetic process [GO:0006564]	cytosol [GO:0005829]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]	NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]
d1psja__d2zp5a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]
d1pskh1_d5juel1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1pskl1_d3ha0a2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1pskl2_d3ciqj___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1psth1_d3du2h2__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	integral component of membrane [GO:0016021]; plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	integral component of membrane [GO:0016021]; plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	integral component of membrane [GO:0016021]; plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]	bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]
d1psza__d1xvlb___1			Firmicutes	Cyanobacteria	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	plasma membrane [GO:0005886]		metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1pt0a1_d3hu3a1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; aspartate 1-decarboxylase activity [GO:0004068]; alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	cytosol [GO:0005829]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	aspartate 1-decarboxylase activity [GO:0004068]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1pt0b__d3hu1d1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; aspartate 1-decarboxylase activity [GO:0004068]; alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	cytosol [GO:0005829]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	aspartate 1-decarboxylase activity [GO:0004068]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1pt2a__d4udka___1			Firmicutes		extracellular region [GO:0005576]; levansucrase activity [GO:0050053]; carbohydrate utilization [GO:0009758]		carbohydrate utilization [GO:0009758]		extracellular region [GO:0005576]		levansucrase activity [GO:0050053]	
d1pt5b__d4hl6a___1			Proteobacteria	Proteobacteria	formyl-CoA transferase activity [GO:0033608]; cellular response to acidic pH [GO:0071468]; oxalate catabolic process [GO:0033611]	acetyl-CoA:oxalate CoA-transferase [GO:0036412]	cellular response to acidic pH [GO:0071468]; oxalate catabolic process [GO:0033611]				formyl-CoA transferase activity [GO:0033608]	acetyl-CoA:oxalate CoA-transferase [GO:0036412]
d1pt7a__d3ubma___1			Proteobacteria	Proteobacteria	formyl-CoA transferase activity [GO:0033608]; cellular response to acidic pH [GO:0071468]; oxalate catabolic process [GO:0033611]	formyl-CoA transferase activity [GO:0033608]; oxalate catabolic process [GO:0033611]	cellular response to acidic pH [GO:0071468]; oxalate catabolic process [GO:0033611]	oxalate catabolic process [GO:0033611]			formyl-CoA transferase activity [GO:0033608]	formyl-CoA transferase activity [GO:0033608]
d1ptga__d3ea1b___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]
d1ptjc__d1n0hb1__1		Fungi	Proteobacteria	Ascomycota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1ptob2_d4j6pc___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d1ptoc1_d1jckb1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]			extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1ptoc1_d2xscc___1			Proteobacteria		extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ptof__d3urya1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1ptoh2_d4pp8b___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; MHC class Ib receptor activity [GO:0032394]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of apoptotic process [GO:0043065]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]		adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of apoptotic process [GO:0043065]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; kinase binding [GO:0019900]; MHC class Ib receptor activity [GO:0032394]; MHC class I protein binding [GO:0042288]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]
d1ptwa__d2heka1__1	Metazoa		Chordata	Aquificae	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	dGTPase activity [GO:0008832]; dGTP catabolic process [GO:0006203]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	dGTP catabolic process [GO:0006203]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]		3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	dGTPase activity [GO:0008832]
d1ptwb__d4muwa___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d1ptzb__d1pu0a___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1pu0c__d2yqxg___1	Metazoa		Chordata		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]		chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	
d1pu0e__d2af2b___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1pu0i__d3gzoi___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1pu3a1_d5m9ca___1	Metazoa	Metazoa	Chordata	Chordata	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]
d1puca__d3qy2b___1	Fungi	Fungi	Ascomycota	Ascomycota	cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; histone binding [GO:0042393]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270]; cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; signaling [GO:0023052]	cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; histone binding [GO:0042393]; protein kinase activator activity [GO:0030295]; protein kinase binding [GO:0019901]; ubiquitin binding [GO:0043130]; cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of mitotic cell cycle [GO:0007346]; regulation of nucleosome density [GO:0060303]; regulation of transcription by RNA polymerase II [GO:0006357]	cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; signaling [GO:0023052]	cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of mitotic cell cycle [GO:0007346]; regulation of nucleosome density [GO:0060303]; regulation of transcription by RNA polymerase II [GO:0006357]	cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; histone binding [GO:0042393]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270]	cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; histone binding [GO:0042393]; protein kinase activator activity [GO:0030295]; protein kinase binding [GO:0019901]; ubiquitin binding [GO:0043130]
d1pumb1_d3ca0a1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1pumb2_d3ah4a2__1	Viridiplantae		Streptophyta		carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]
d1pumb2_d3c9za1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1puna__d3fk9b1__1			Proteobacteria	Firmicutes	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	hydrolase activity [GO:0016787]	DNA repair [GO:0006281]; DNA replication [GO:0006260]				8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]	hydrolase activity [GO:0016787]
d1puub3_d1qxma2__1	Viridiplantae		Streptophyta		carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]
d1puub3_d3ca0a2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1puub4_d4zfwb1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1pv4c2_d5vl1a1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	lysyl-tRNA aminoacylation [GO:0006430]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d1pv4e2_d1il2b1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]
d1pv9b1_d1wlra1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; proline dipeptidase activity [GO:0102009]	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]			cytoplasm [GO:0005737]	cytosol [GO:0005829]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; proline dipeptidase activity [GO:0102009]	aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]
d1pvc1__d1yc6f___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1pvha1_d6b2dd___1	Metazoa		Chordata	Proteobacteria	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	integral component of plasma membrane [GO:0005887]; inorganic anion transmembrane transporter activity [GO:0015103]	ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]		ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	integral component of plasma membrane [GO:0005887]	ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]	inorganic anion transmembrane transporter activity [GO:0015103]
d1pvma4_d3fv6a___1			Euryarchaeota	Firmicutes	metal ion binding [GO:0046872]	DNA binding [GO:0003677]; carbon catabolite repression of transcription [GO:0045013]		carbon catabolite repression of transcription [GO:0045013]			metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d1pvmb4_d5x9gb2__1			Euryarchaeota	Deinococcus-Thermus	metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; magnesium ion transmembrane transporter activity [GO:0015095]; protein homodimerization activity [GO:0042803]; magnesium ion transport [GO:0015693]		magnesium ion transport [GO:0015693]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; magnesium ion transmembrane transporter activity [GO:0015095]; protein homodimerization activity [GO:0042803]
d1pvoc2_d4dama1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]	DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]	cytosol [GO:0005829]; membrane [GO:0016020]		ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]	single-stranded DNA binding [GO:0003697]
d1pvsa1_d4ai5a1__1			Proteobacteria		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	
d1pvsa2_d1qnaa2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1pw3a__d1kcvh2__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1pw3a__d1uwgh1__1	Metazoa		Chordata									
d1pw9b1_d2bpha1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1pw9c1_d3cada___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cell adhesion [GO:0007155]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]
d1pwbc1_d4n34a___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1pweb__d3x43e___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]; gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]	cysteine synthase activity [GO:0004124]; antibiotic biosynthetic process [GO:0017000]; cysteine biosynthetic process from serine [GO:0006535]	gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]	antibiotic biosynthetic process [GO:0017000]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]		L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]	cysteine synthase activity [GO:0004124]
d1pwhd__d4kkxb___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]; gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]	tryptophan biosynthetic process [GO:0000162]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]
d1pwka__d3dvtd___1	Metazoa	Metazoa	Chordata	Arthropoda	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; glutamatergic synapse [GO:0098978]; microtubule [GO:0005874]; myosin V complex [GO:0031475]; postsynaptic density [GO:0014069]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; microtubule-based process [GO:0007017]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]	cell [GO:0005623]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]; disordered domain specific binding [GO:0097718]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein homodimerization activity [GO:0042803]; actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; oogenesis [GO:0048477]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; sperm individualization [GO:0007291]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; wing disc development [GO:0035220]	microtubule-based process [GO:0007017]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]	actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; oogenesis [GO:0048477]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; sperm individualization [GO:0007291]; wing disc development [GO:0035220]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; glutamatergic synapse [GO:0098978]; microtubule [GO:0005874]; myosin V complex [GO:0031475]; postsynaptic density [GO:0014069]	cell [GO:0005623]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]	dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]	disordered domain specific binding [GO:0097718]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein homodimerization activity [GO:0042803]
d1pwoc__d2g58a___1		Metazoa		Chordata		extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]		arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]		extracellular region [GO:0005576]		calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1pwqa2_d5i2zb___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1pwqb2_d1pwwb2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d1pwua1_d4mtwe___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1pwua2_d1gw6a3__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1pwua3_d4h03a1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	extracellular region [GO:0005576]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d1pwub1_d3g42b___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d1pwub2_d2i47d___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d1pwwa1_d1pwpa2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d1pwxa__d2x86d___1			Proteobacteria	Proteobacteria		ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]		ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]				ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]
d1pwxc__d4g81b___1			Proteobacteria									
d1pwzb__d4a5oa2__1			Proteobacteria	Proteobacteria		cytosol [GO:0005829]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]		histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]		cytosol [GO:0005829]		methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]
d1px0b__d1keta___1			Proteobacteria	Firmicutes		dTDP-glucose 4,6-dehydratase activity [GO:0008460]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]				dTDP-glucose 4,6-dehydratase activity [GO:0008460]
d1px0c__d1x0xa1__1		Metazoa	Proteobacteria	Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycerol-3-phosphate dehydrogenase (quinone) activity [GO:0004368]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophosphate shuttle [GO:0006127]; NADH oxidation [GO:0006116]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of glycolytic process [GO:0045821]		cellular response to cAMP [GO:0071320]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophosphate shuttle [GO:0006127]; NADH oxidation [GO:0006116]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of glycolytic process [GO:0045821]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]		glycerol-3-phosphate dehydrogenase (quinone) activity [GO:0004368]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]
d1px0d__d1kepb___1			Proteobacteria	Firmicutes		dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]; nucleotide-sugar metabolic process [GO:0009225]		nucleotide-sugar metabolic process [GO:0009225]				dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]
d1px2a1_d1i7la1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of synaptic vesicle membrane [GO:0098993]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of synaptic vesicle membrane [GO:0098850]; Golgi apparatus [GO:0005794]; intracellular organelle [GO:0043229]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; synaptonemal complex [GO:0000795]; terminal bouton [GO:0043195]; actin binding [GO:0003779]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; neuron development [GO:0048666]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle cycle [GO:0098693]; synapse organization [GO:0050808]; synaptic vesicle clustering [GO:0097091]	cell junction [GO:0030054]; extrinsic component of synaptic vesicle membrane [GO:0098850]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; cytoskeletal protein binding [GO:0008092]; neurotransmitter secretion [GO:0007269]; regulation of neurotransmitter secretion [GO:0046928]	neuron development [GO:0048666]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle cycle [GO:0098693]; synapse organization [GO:0050808]; synaptic vesicle clustering [GO:0097091]	neurotransmitter secretion [GO:0007269]; regulation of neurotransmitter secretion [GO:0046928]	anchored component of synaptic vesicle membrane [GO:0098993]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of synaptic vesicle membrane [GO:0098850]; Golgi apparatus [GO:0005794]; intracellular organelle [GO:0043229]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; synaptonemal complex [GO:0000795]; terminal bouton [GO:0043195]	cell junction [GO:0030054]; extrinsic component of synaptic vesicle membrane [GO:0098850]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	actin binding [GO:0003779]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]	ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; cytoskeletal protein binding [GO:0008092]
d1px3a1_d1ghol2__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d1px3a1_d3dyoc4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1px3a5_d2vzsb5__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1px3b1_d3muz14__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1px3c2_d3e1f32__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1px3c3_d1wzxc1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]
d1px3d5_d4gzja___1		Viridiplantae	Proteobacteria	Streptophyta	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]
d1px4a2_d1jz6d1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1px4a3_d1tg7a2__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; beta-galactosidase activity [GO:0004565]; galactose binding [GO:0005534]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-galactosidase activity [GO:0004565]; galactose binding [GO:0005534]
d1px4a4_d1o7d.2__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lysosome [GO:0005764]; vacuolar membrane [GO:0005774]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; learning or memory [GO:0007611]; mannose metabolic process [GO:0006013]; protein deglycosylation [GO:0006517]	lactose catabolic process [GO:0005990]	learning or memory [GO:0007611]; mannose metabolic process [GO:0006013]; protein deglycosylation [GO:0006517]	beta-galactosidase complex [GO:0009341]	lysosome [GO:0005764]; vacuolar membrane [GO:0005774]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1px4a5_d2zx9b1__1			Proteobacteria	Thermotogae	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	lactose catabolic process [GO:0005990]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	beta-galactosidase complex [GO:0009341]	lysosome [GO:0005764]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-L-fucosidase activity [GO:0004560]
d1px4b1_d3muy34__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1px4b4_d2f2hd2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1px4b4_d3vd7b5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1px4c1_d2vztb5__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1px4c4_d3t2qb5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1px4d2_d3t0ac2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1px4d4_d3t2od5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1px5a1_d4jlxa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 2'-5'-oligoadenylate synthetase activity [GO:0001730]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; purine nucleotide biosynthetic process [GO:0006164]; regulation of ribonuclease activity [GO:0060700]	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; purine nucleotide biosynthetic process [GO:0006164]; regulation of ribonuclease activity [GO:0060700]	activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]	2'-5'-oligoadenylate synthetase activity [GO:0001730]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]
d1px7a2_d4jrrb___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; periplasmic space [GO:0042597]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	protein disulfide oxidoreductase activity [GO:0015035]
d1px7b1_d1gsdc1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1px7b1_d2c3nd2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]
d1px7b2_d5b8bh___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]; activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]
d1px8a2_d2xvpb1__1		Fungi	Firmicutes	Ascomycota	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			xylan 1,4-beta-xylosidase activity [GO:0009044]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1pxca2_d3cpih3__1		Fungi	Proteobacteria	Ascomycota	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	cytoplasm [GO:0005737]; GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	benzoate catabolic process via hydroxylation [GO:0043640]	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]		cytoplasm [GO:0005737]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]
d1pxua__d1d2ba___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; basal part of cell [GO:0045178]; basement membrane [GO:0005604]; cell junction [GO:0030054]; extracellular matrix [GO:0031012]; extracellular matrix of synaptic cleft [GO:0098965]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; synapse [GO:0045202]; acetylcholine receptor regulator activity [GO:0030548]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; extracellular matrix binding [GO:0050840]; glycosaminoglycan binding [GO:0005539]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; laminin binding [GO:0043236]; laminin-1 binding [GO:0043237]; serine-type endopeptidase inhibitor activity [GO:0004867]; sialic acid binding [GO:0033691]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; negative regulation of neuron projection development [GO:0010977]; negative regulation of serine-type peptidase activity [GO:1902572]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]	basement membrane [GO:0005604]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; metalloendopeptidase inhibitor activity [GO:0008191]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; zinc ion binding [GO:0008270]; aging [GO:0007568]; cartilage development [GO:0051216]; cell activation [GO:0001775]; cellular protein metabolic process [GO:0044267]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of trophoblast cell migration [GO:1901164]; platelet degranulation [GO:0002576]; positive regulation of cell population proliferation [GO:0008284]; post-translational protein modification [GO:0043687]; regulation of integrin-mediated signaling pathway [GO:2001044]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to organic substance [GO:0010033]; response to peptide hormone [GO:0043434]	actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; negative regulation of neuron projection development [GO:0010977]; negative regulation of serine-type peptidase activity [GO:1902572]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]	aging [GO:0007568]; cartilage development [GO:0051216]; cell activation [GO:0001775]; cellular protein metabolic process [GO:0044267]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of trophoblast cell migration [GO:1901164]; platelet degranulation [GO:0002576]; positive regulation of cell population proliferation [GO:0008284]; post-translational protein modification [GO:0043687]; regulation of integrin-mediated signaling pathway [GO:2001044]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to organic substance [GO:0010033]; response to peptide hormone [GO:0043434]	axon [GO:0030424]; basal part of cell [GO:0045178]; basement membrane [GO:0005604]; cell junction [GO:0030054]; extracellular matrix [GO:0031012]; extracellular matrix of synaptic cleft [GO:0098965]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; synapse [GO:0045202]	basement membrane [GO:0005604]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]	acetylcholine receptor regulator activity [GO:0030548]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; extracellular matrix binding [GO:0050840]; glycosaminoglycan binding [GO:0005539]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; laminin-1 binding [GO:0043237]; laminin binding [GO:0043236]; serine-type endopeptidase inhibitor activity [GO:0004867]; sialic acid binding [GO:0033691]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; metalloendopeptidase inhibitor activity [GO:0008191]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; zinc ion binding [GO:0008270]
d1pxwb__d1njih___1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; ribosome biogenesis [GO:0042254]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome biogenesis [GO:0042254]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	translation [GO:0006412]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]	ribosome [GO:0005840]	ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1pxxa1_d1aefa___1	Metazoa	Fungi	Chordata	Ascomycota	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1pxxb1_d3pghc1__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1pxza__d2iq7g___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	pectin catabolic process [GO:0045490]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	polygalacturonase activity [GO:0004650]
d1py0a1_d1kbvb2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]	cell outer membrane [GO:0009279]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1py1a__d4hfgb___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II, holoenzyme [GO:0016591]; identical protein binding [GO:0042802]; RNA polymerase II complex binding [GO:0000993]; dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; mRNA 3'-end processing [GO:0031124]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle process [GO:0010564]; snRNA transcription by RNA polymerase II [GO:0042795]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; mRNA 3'-end processing [GO:0031124]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle process [GO:0010564]; snRNA transcription by RNA polymerase II [GO:0042795]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II, holoenzyme [GO:0016591]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	identical protein binding [GO:0042802]; RNA polymerase II complex binding [GO:0000993]
d1py1c__d5loza1__1	Metazoa	Fungi	Chordata	Ascomycota	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; clathrin binding [GO:0030276]; lipid binding [GO:0008289]; ubiquitin binding [GO:0043130]; actin cortical patch assembly [GO:0000147]; actin filament organization [GO:0007015]; endocytosis [GO:0006897]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	actin cortical patch assembly [GO:0000147]; actin filament organization [GO:0007015]; endocytosis [GO:0006897]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	clathrin binding [GO:0030276]; lipid binding [GO:0008289]; ubiquitin binding [GO:0043130]
d1py1d__d1h0aa___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; extrinsic component of postsynaptic membrane [GO:0098890]; extrinsic component of presynaptic membrane [GO:0098888]; nucleus [GO:0005634]; postsynapse [GO:0098794]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; terminal bouton [GO:0043195]; clathrin adaptor activity [GO:0035615]; ion channel binding [GO:0044325]; lipid binding [GO:0008289]; transcription factor binding [GO:0008134]; endocytosis [GO:0006897]; positive regulation of clathrin coat assembly [GO:1905445]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	endocytosis [GO:0006897]; positive regulation of clathrin coat assembly [GO:1905445]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; extrinsic component of postsynaptic membrane [GO:0098890]; extrinsic component of presynaptic membrane [GO:0098888]; nucleus [GO:0005634]; postsynapse [GO:0098794]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; terminal bouton [GO:0043195]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	clathrin adaptor activity [GO:0035615]; ion channel binding [GO:0044325]; lipid binding [GO:0008289]; transcription factor binding [GO:0008134]
d1py3a__d7rnta___1		Fungi	Actinobacteria	Ascomycota	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]				cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1py4a__d1acyl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1py4a__d5ebga___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; T cell mediated immunity [GO:0002456]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; T cell mediated immunity [GO:0002456]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1py4b__d4wwif1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1py4d__d4hc1b2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; integrin binding involved in cell-matrix adhesion [GO:0098640]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	integrin binding involved in cell-matrix adhesion [GO:0098640]
d1pyba__d1xprb2__1			Aquificae	Proteobacteria	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; methionyl-tRNA aminoacylation [GO:0006431]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	methionyl-tRNA aminoacylation [GO:0006431]	DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; membrane [GO:0016020]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]
d1pybd__d1gd7b___1			Aquificae	Deinococcus-Thermus	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; methionyl-tRNA aminoacylation [GO:0006431]	tRNA binding [GO:0000049]	methionyl-tRNA aminoacylation [GO:0006431]				ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]	tRNA binding [GO:0000049]
d1pyda3_d1mczp3__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1pydb3_d1mczd3__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1pydb3_d1um9b1__1	Fungi		Ascomycota	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]
d1pypa__d3i98e___1	Fungi		Ascomycota	Euryarchaeota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1pysa__d2djza1__1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	phenylalanyl-tRNA aminoacylation [GO:0006432]	cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d1pysb3_d1pxfa1__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]		phenylalanyl-tRNA aminoacylation [GO:0006432]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]	
d1pyta__d1itpa1__1	Metazoa	Fungi	Chordata	Basidiomycota	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	serine-type endopeptidase inhibitor activity [GO:0004867]	proteolysis [GO:0006508]		extracellular space [GO:0005615]		metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1pywb1_d1a6td1__1	Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	
d1pywb2_d4z7wb1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	nutrient reservoir activity [GO:0045735]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	nutrient reservoir activity [GO:0045735]
d1pywd2_d3mfga2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	
d1pz2a2_d1mxda2__1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		alpha-L-arabinofuranosidase activity [GO:0046556]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1pz3a2_d1k6aa___1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]		alpha-L-arabinofuranosidase activity [GO:0046556]	endo-1,4-beta-xylanase activity [GO:0031176]
d1pz5a2_d3l3gb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1pz5b1_d1u91b1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1pz5b2_d1ydpb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1pzaa__d2pp7b2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1pzaa__d3in0a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1pzda1_d1iu1b___1	Metazoa	Metazoa	Chordata	Chordata	COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; structural molecule activity [GO:0005198]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; organelle transport along microtubule [GO:0072384]; protein secretion [GO:0009306]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; recycling endosome [GO:0055037]; trans-Golgi network membrane [GO:0032588]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; Rab GTPase binding [GO:0017137]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; regulation of defense response to virus by virus [GO:0050690]	endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; organelle transport along microtubule [GO:0072384]; protein secretion [GO:0009306]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; regulation of defense response to virus by virus [GO:0050690]	COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; recycling endosome [GO:0055037]; trans-Golgi network membrane [GO:0032588]	structural molecule activity [GO:0005198]	GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; Rab GTPase binding [GO:0017137]
d1pzfa2_d2j5qa2__1			Apicomplexa	Euryarchaeota	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	L-malate dehydrogenase activity [GO:0030060]
d1pzfc1_d2hlpa1__1			Apicomplexa	Euryarchaeota	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	L-malate dehydrogenase activity [GO:0030060]
d1pzfc2_d1ib6c2__1			Apicomplexa	Proteobacteria	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]
d1pzga2_d4aj1d2__1		Metazoa	Apicomplexa	Chordata	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1pzha1_d5jyde___1			Apicomplexa	Proteobacteria	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]				L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1pzhb1_d1xkqc___1		Metazoa	Apicomplexa	Nematoda (roundworms)	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]				L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1pzhb2_d3fi9b2__1			Apicomplexa	Bacteroidetes	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	malate dehydrogenase activity [GO:0016615]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]			L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	malate dehydrogenase activity [GO:0016615]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d1pzhc1_d4i9ub1__1		Metazoa	Apicomplexa	Chordata	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	L-lactate dehydrogenase activity [GO:0004459]
d1pzhd2_d4wlud2__1		Metazoa	Apicomplexa	Chordata	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d1pzid__d1ha5c1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1pzjd__d2nttb1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]
d1pzjd__d2xsca___1			Proteobacteria		extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		toxin activity [GO:0090729]
d1pzkh__d1ct1e___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]		galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d1pzta__d1nqib___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1pzub1_d2dlga1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d1pzuh1_d4ffya___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1pzui1_d1j0hb1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]		chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1pzum1_d3vgga1__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	trehalose biosynthetic process [GO:0005992]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]
d1pzum2_d1nfka2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1pzxb__d1un9a4__1			Firmicutes	Proteobacteria	lipid binding [GO:0008289]	ATP binding [GO:0005524]; glycerone kinase activity [GO:0004371]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; anaerobic glycerol catabolic process [GO:0019588]		anaerobic glycerol catabolic process [GO:0019588]			lipid binding [GO:0008289]	ATP binding [GO:0005524]; glycerone kinase activity [GO:0004371]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d1pzya__d150lb___1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	host cell cytoplasm [GO:0030430]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	lysozyme activity [GO:0003796]
d1pzyc__d1g0ma___1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	host cell cytoplasm [GO:0030430]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	lysozyme activity [GO:0003796]
d1pzyc__d5kxpa___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1pzyd__d1mp5b___1	Metazoa		Chordata	Proteobacteria	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]		alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]
d1pzza__d3k1xa___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1q03a__d3ud7a___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1q0ca1_d3ojtd2__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1q0cb1_d1knfa2__1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]		aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]
d1q0db__d3g4zb___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d1q0gi__d1t6ui___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d1q0kg__d4ncqb___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d1q0la3_d1crwr2__1		Metazoa	Proteobacteria	Arthropoda	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1q0ob2_d3ojtb1__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1q0qb3_d1u8fq2__1		Metazoa	Proteobacteria	Chordata	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]	aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]
d1q0ra__d5e2ia___1		Metazoa	Actinobacteria	Chordata	aclacinomycin A methylesterase activity [GO:0102542]; aclacinomycin T methylesterase activity [GO:0102530]; carboxylic ester hydrolase activity [GO:0052689]; epsilon-rhodomycinone methylesterase activity [GO:0102543]; antibiotic biosynthetic process [GO:0017000]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	antibiotic biosynthetic process [GO:0017000]	acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	aclacinomycin A methylesterase activity [GO:0102542]; aclacinomycin T methylesterase activity [GO:0102530]; carboxylic ester hydrolase activity [GO:0052689]; epsilon-rhodomycinone methylesterase activity [GO:0102543]	acetylcholinesterase activity [GO:0003990]
d1q0xh1_d1z3gm1__1	Metazoa		Chordata	Apicomplexa	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]		calcium ion binding [GO:0005509]
d1q0xl1_d5umnf1__1	Metazoa		Chordata	Negarnaviricota	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d1q0yh1_d1g7la___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1q0yl2_d5u1rd1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1q12d2_d3b5yb1__1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]; activating transcription factor binding [GO:0033613]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]	maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	activating transcription factor binding [GO:0033613]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; ATP binding [GO:0005524]	ATPase activity [GO:0016887]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]
d1q13a__d4h8na___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity [GO:0047006]; prostaglandin-E2 9-reductase activity [GO:0050221]; prostaglandin biosynthetic process [GO:0001516]	2-dehydropantolactone reductase (A-specific) activity [GO:0047011]; aldo-keto reductase (NADP) activity [GO:0004033]; cellular ketone metabolic process [GO:0042180]	prostaglandin biosynthetic process [GO:0001516]	cellular ketone metabolic process [GO:0042180]	cytoplasm [GO:0005737]		17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity [GO:0047006]; prostaglandin-E2 9-reductase activity [GO:0050221]	2-dehydropantolactone reductase (A-specific) activity [GO:0047011]; aldo-keto reductase (NADP) activity [GO:0004033]
d1q15d2_d1xfgb___1			Proteobacteria	Proteobacteria	asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]; antibiotic biosynthetic process [GO:0017000]; asparagine biosynthetic process [GO:0006529]	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	antibiotic biosynthetic process [GO:0017000]; asparagine biosynthetic process [GO:0006529]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]		cytosol [GO:0005829]	asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]
d1q16a1_d1pt1a1__1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]	cytosol [GO:0005829]; aspartate 1-decarboxylase activity [GO:0004068]; alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]	alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]	aspartate 1-decarboxylase activity [GO:0004068]
d1q19a1_d1efpd___1			Proteobacteria	Proteobacteria	asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]; antibiotic biosynthetic process [GO:0017000]; asparagine biosynthetic process [GO:0006529]	electron transfer activity [GO:0009055]	antibiotic biosynthetic process [GO:0017000]; asparagine biosynthetic process [GO:0006529]				asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]	electron transfer activity [GO:0009055]
d1q1bc1_d1guod___1			Proteobacteria	Firmicutes	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]; activating transcription factor binding [GO:0033613]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	molybdate ion transport [GO:0015689]	maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	molybdate ion transport [GO:0015689]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]		activating transcription factor binding [GO:0033613]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; ATP binding [GO:0005524]	
d1q1ca2_d4drna1__1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein-containing complex localization [GO:0031503]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein-containing complex localization [GO:0031503]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1q1fa__d3pi1a___1	Metazoa	Metazoa	Chordata	Mollusca	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1q1gf__d1zosa___1			Apicomplexa	Firmicutes	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]	nucleoside metabolic process [GO:0009116]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]		cytosol [GO:0005829]	purine-nucleoside phosphorylase activity [GO:0004731]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d1q1jh1_d3bhba1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1q1jm1_d2r0kh1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	proteolysis [GO:0006508]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1q1jm2_d3pp3l1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	
d1q1ka1_d2f36c___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	histidine biosynthetic process [GO:0000105]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	cytosol [GO:0005829]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d1q1pa1_d4zmqb1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d1q1pa1_d4zt1a2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1q1pa2_d3k6fb1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]
d1q1sc1_d3b7sa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1q1tc__d4u5na___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]	histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]	histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]
d1q20a1_d4jvmb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; alcohol sulfotransferase activity [GO:0004027]; cholesterol binding [GO:0015485]; nucleic acid binding [GO:0003676]; steroid hormone binding [GO:1990239]; steroid sulfotransferase activity [GO:0050294]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; cholesterol metabolic process [GO:0008203]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of epidermal cell differentiation [GO:0045606]; steroid metabolic process [GO:0008202]; sulfate assimilation [GO:0000103]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; estrone sulfotransferase activity [GO:0004304]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid binding [GO:0005496]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; estrogen catabolic process [GO:0006711]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; positive regulation of fat cell differentiation [GO:0045600]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; cholesterol metabolic process [GO:0008203]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of epidermal cell differentiation [GO:0045606]; steroid metabolic process [GO:0008202]; sulfate assimilation [GO:0000103]	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; estrogen catabolic process [GO:0006711]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; positive regulation of fat cell differentiation [GO:0045600]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]	alcohol sulfotransferase activity [GO:0004027]; cholesterol binding [GO:0015485]; nucleic acid binding [GO:0003676]; steroid hormone binding [GO:1990239]; steroid sulfotransferase activity [GO:0050294]	estrone sulfotransferase activity [GO:0004304]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid binding [GO:0005496]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]
d1q21a__d5m6xb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; cadherin binding [GO:0045296]; GTPase activator activity [GO:0005096]; Rab GTPase binding [GO:0017137]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; endosomal transport [GO:0016197]; negative regulation of endocytic recycling [GO:2001136]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; small GTPase mediated signal transduction [GO:0007264]; transferrin transport [GO:0033572]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	endosomal transport [GO:0016197]; negative regulation of endocytic recycling [GO:2001136]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; small GTPase mediated signal transduction [GO:0007264]; transferrin transport [GO:0033572]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	cadherin binding [GO:0045296]; GTPase activator activity [GO:0005096]; Rab GTPase binding [GO:0017137]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]
d1q23a__d1dpca___1			Proteobacteria	Proteobacteria	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	response to antibiotic [GO:0046677]	glycolytic process [GO:0006096]		pyruvate dehydrogenase complex [GO:0045254]	chloramphenicol O-acetyltransferase activity [GO:0008811]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]
d1q23a__d2ii3a___1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	response to antibiotic [GO:0046677]			cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	chloramphenicol O-acetyltransferase activity [GO:0008811]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1q23d__d2ii4f___1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	response to antibiotic [GO:0046677]			cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	chloramphenicol O-acetyltransferase activity [GO:0008811]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1q23e__d1b5sd___1			Proteobacteria	Firmicutes	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	response to antibiotic [GO:0046677]	glycolytic process [GO:0006096]			chloramphenicol O-acetyltransferase activity [GO:0008811]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]
d1q23e__d2ihwc___1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	response to antibiotic [GO:0046677]			cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	chloramphenicol O-acetyltransferase activity [GO:0008811]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1q23g__d3l60a___1			Proteobacteria	Actinobacteria	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; oxidation-reduction process [GO:0055114]	response to antibiotic [GO:0046677]	oxidation-reduction process [GO:0055114]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	chloramphenicol O-acetyltransferase activity [GO:0008811]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]
d1q23i__d1b5sa___1			Proteobacteria	Firmicutes	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	response to antibiotic [GO:0046677]	glycolytic process [GO:0006096]			chloramphenicol O-acetyltransferase activity [GO:0008811]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]
d1q23l__d2ii5d___1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	response to antibiotic [GO:0046677]			cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	chloramphenicol O-acetyltransferase activity [GO:0008811]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1q27a__d5c7ta___1			Deinococcus-Thermus	Proteobacteria	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	ADP-ribose diphosphatase activity [GO:0047631]					hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	ADP-ribose diphosphatase activity [GO:0047631]
d1q2eb__d1qdob___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1q2la1_d1joeb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]; quorum sensing [GO:0009372]	proteolysis [GO:0006508]	quorum sensing [GO:0009372]	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]		metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]
d1q2la2_d3cxha1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	proteolysis [GO:0006508]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	
d1q2vb2_d1kpoy2__1			Euryarchaeota		ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]		protein folding [GO:0006457]				ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]	
d1q34a__d2fo3a1__1	Metazoa		Nematoda (roundworms)	Apicomplexa	HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; ubiquitin conjugating enzyme complex [GO:0031371]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]		DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]		HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; ubiquitin conjugating enzyme complex [GO:0031371]		ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]	
d1q34b__d2f0ra___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; ubiquitin conjugating enzyme complex [GO:0031371]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]; autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; ubiquitin conjugating enzyme complex [GO:0031371]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]	calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]
d1q3fa1_d4ws5a___1	Metazoa		Chordata	Actinobacteria	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d1q3kb__d3a6ld___1			Proteobacteria	Proteobacteria	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]			creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]
d1q3rc2_d1pf9i2__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d1q3sc2_d1assa___1			Euryarchaeota	Euryarchaeota	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	protein folding [GO:0006457]	protein folding [GO:0006457]			ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1q4ga1_d1aeka___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1q4jb1_d4dejc2__1			Apicomplexa	Proteobacteria	glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]					glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d1q4jb2_d3h8qa1__1		Metazoa	Apicomplexa	Chordata	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin-disulfide reductase activity [GO:0004791]; cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]		cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	glutathione transferase activity [GO:0004364]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin-disulfide reductase activity [GO:0004791]
d1q4ka1_d5lhxa___1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]; anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; spindle pole [GO:0000922]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]; centriole replication [GO:0007099]; centrosome cycle [GO:0007098]; male meiotic nuclear division [GO:0007140]; mitotic cell cycle [GO:0000278]; positive regulation of protein catabolic process [GO:0045732]; protein autophosphorylation [GO:0046777]; regulation of centriole replication [GO:0046599]; regulation of cytokinesis [GO:0032465]; regulation of protein stability [GO:0031647]; sperm axoneme assembly [GO:0007288]; syncytial blastoderm mitotic cell cycle [GO:0035186]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	centriole replication [GO:0007099]; centrosome cycle [GO:0007098]; male meiotic nuclear division [GO:0007140]; mitotic cell cycle [GO:0000278]; positive regulation of protein catabolic process [GO:0045732]; protein autophosphorylation [GO:0046777]; regulation of centriole replication [GO:0046599]; regulation of cytokinesis [GO:0032465]; regulation of protein stability [GO:0031647]; sperm axoneme assembly [GO:0007288]; syncytial blastoderm mitotic cell cycle [GO:0035186]	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]	centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; spindle pole [GO:0000922]	anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]
d1q4kc1_d5lhza___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]; anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; centrosome duplication [GO:0051298]; determination of left/right symmetry [GO:0007368]; embryonic axis specification [GO:0000578]; floor plate development [GO:0033504]; forebrain development [GO:0030900]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; mitotic spindle organization [GO:0007052]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord development [GO:0030903]; protein localization to centrosome [GO:0071539]; regulation of centriole replication [GO:0046599]; smoothened signaling pathway [GO:0007224]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	centrosome duplication [GO:0051298]; determination of left/right symmetry [GO:0007368]; embryonic axis specification [GO:0000578]; floor plate development [GO:0033504]; forebrain development [GO:0030900]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; mitotic spindle organization [GO:0007052]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord development [GO:0030903]; protein localization to centrosome [GO:0071539]; regulation of centriole replication [GO:0046599]; smoothened signaling pathway [GO:0007224]	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]	centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]	identical protein binding [GO:0042802]
d1q4nx2_d1ghon5__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular exosome [GO:0070062]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	
d1q4sb__d2h4uc___1		Metazoa	Actinobacteria	Chordata	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]; acyl-CoA hydrolase activity [GO:0047617]; acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]		acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	acyl-CoA hydrolase activity [GO:0047617]
d1q50a__d2puvb___1		Fungi		Ascomycota	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; cell wall chitin biosynthetic process [GO:0006038]; cellular response to drug [GO:0035690]; chitin biosynthetic process [GO:0006031]; fructose 6-phosphate metabolic process [GO:0006002]; fungal-type cell wall chitin biosynthetic process [GO:0034221]; glucosamine biosynthetic process [GO:0006042]; glutamine metabolic process [GO:0006541]; hyphal growth [GO:0030448]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cellular response to drug [GO:0035690]; cell wall chitin biosynthetic process [GO:0006038]; chitin biosynthetic process [GO:0006031]; fructose 6-phosphate metabolic process [GO:0006002]; fungal-type cell wall chitin biosynthetic process [GO:0034221]; glucosamine biosynthetic process [GO:0006042]; glutamine metabolic process [GO:0006541]; hyphal growth [GO:0030448]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytoplasm [GO:0005737]		glucose-6-phosphate isomerase activity [GO:0004347]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]
d1q53a1_d1tr0b___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytosol [GO:0005829]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; pollen tube adhesion [GO:0009865]		defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; pollen tube adhesion [GO:0009865]		cytosol [GO:0005829]; plasma membrane [GO:0005886]		metal ion binding [GO:0046872]	
d1q53b1_d1tr0d___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytosol [GO:0005829]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; pollen tube adhesion [GO:0009865]		defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; pollen tube adhesion [GO:0009865]		cytosol [GO:0005829]; plasma membrane [GO:0005886]		metal ion binding [GO:0046872]	
d1q54a__d1puqa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]		hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]
d1q56a1_d2r49a___1	Metazoa		Chordata	Fibrobacteres	axon [GO:0030424]; basal part of cell [GO:0045178]; basement membrane [GO:0005604]; cell junction [GO:0030054]; extracellular matrix [GO:0031012]; extracellular matrix of synaptic cleft [GO:0098965]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; synapse [GO:0045202]; acetylcholine receptor regulator activity [GO:0030548]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; extracellular matrix binding [GO:0050840]; glycosaminoglycan binding [GO:0005539]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; laminin binding [GO:0043236]; laminin-1 binding [GO:0043237]; serine-type endopeptidase inhibitor activity [GO:0004867]; sialic acid binding [GO:0033691]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; negative regulation of neuron projection development [GO:0010977]; negative regulation of serine-type peptidase activity [GO:1902572]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; negative regulation of neuron projection development [GO:0010977]; negative regulation of serine-type peptidase activity [GO:1902572]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]	carbohydrate metabolic process [GO:0005975]	axon [GO:0030424]; basal part of cell [GO:0045178]; basement membrane [GO:0005604]; cell junction [GO:0030054]; extracellular matrix [GO:0031012]; extracellular matrix of synaptic cleft [GO:0098965]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; synapse [GO:0045202]		acetylcholine receptor regulator activity [GO:0030548]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; extracellular matrix binding [GO:0050840]; glycosaminoglycan binding [GO:0005539]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; laminin-1 binding [GO:0043237]; laminin binding [GO:0043236]; serine-type endopeptidase inhibitor activity [GO:0004867]; sialic acid binding [GO:0033691]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]	licheninase activity [GO:0042972]
d1q5hc1_d5y5od___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1q5la__d3c7nb1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein refolding [GO:0042026]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d1q5mb__d3dn5a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity [GO:0047006]; prostaglandin-E2 9-reductase activity [GO:0050221]; prostaglandin biosynthetic process [GO:0001516]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	prostaglandin biosynthetic process [GO:0001516]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity [GO:0047006]; prostaglandin-E2 9-reductase activity [GO:0050221]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d1q5qh__d2f16i___1		Fungi	Actinobacteria	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1q5qj__d1ya7g___1			Actinobacteria		cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	proteasome activator complex [GO:0008537]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	
d1q5ql__d1z7qg1__1		Fungi	Actinobacteria	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1q5qn__d3shjr___1		Fungi	Actinobacteria	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1q5xc__d3c8oa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; ribonuclease inhibitor activity [GO:0008428]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of RNA catabolic process [GO:1902369]	4-hydroxy-4-methyl-2-oxoglutarate aldolase activity [GO:0047443]; metal ion binding [GO:0046872]; oxaloacetate decarboxylase activity [GO:0008948]; ribonuclease inhibitor activity [GO:0008428]; regulation of RNA metabolic process [GO:0051252]	negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of RNA catabolic process [GO:1902369]	regulation of RNA metabolic process [GO:0051252]	cytosol [GO:0005829]		endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; ribonuclease inhibitor activity [GO:0008428]	4-hydroxy-4-methyl-2-oxoglutarate aldolase activity [GO:0047443]; metal ion binding [GO:0046872]; oxaloacetate decarboxylase activity [GO:0008948]; ribonuclease inhibitor activity [GO:0008428]
d1q6ca__d2xgba___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; identical protein binding [GO:0042802]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; identical protein binding [GO:0042802]
d1q6da__d1bpl.1__1	Viridiplantae		Streptophyta	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1q6da__d3scnb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d1q6ea__d1v3ja4__1	Viridiplantae		Streptophyta	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1q6ea__d3mv023__1	Viridiplantae		Streptophyta	Proteobacteria	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1q6ga__d3mmuc___1	Viridiplantae		Streptophyta	Thermotogae	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	polysaccharide catabolic process [GO:0000272]	cellular glucan metabolic process [GO:0006073]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1q6rb__d1xbzb___1			Proteobacteria	Proteobacteria	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]			3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1q6sa1_d1q6ma1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1q6sa1_d2gwoa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dephosphorylation [GO:0016311]; meiotic cell cycle [GO:0051321]; protein dephosphorylation [GO:0006470]; spermatogenesis [GO:0007283]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	dephosphorylation [GO:0016311]; meiotic cell cycle [GO:0051321]; protein dephosphorylation [GO:0006470]; spermatogenesis [GO:0007283]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]		cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1q6tb1_d1kaka___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1q6tb1_d2nv5c___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	axon [GO:0030424]; cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	axon [GO:0030424]; cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]
d1q6xa2_d2h3ua1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]; choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]; acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]	carnitine O-acetyltransferase activity [GO:0004092]
d1q6xb1_d2fw3a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]; choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]; acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]	carnitine O-palmitoyltransferase activity [GO:0004095]
d1q6xb2_d4epha1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]; choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]; acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]	carnitine O-palmitoyltransferase activity [GO:0004095]
d1q6za1_d4j1tc___1			Proteobacteria	Deinococcus-Thermus	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]	mandelate catabolic process [GO:0019596]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]
d1q6za2_d4ju8a3__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	mandelate catabolic process [GO:0019596]	mandelate catabolic process [GO:0019596]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1q72h1_d1y0la2__1												
d1q72l1_d1ktke2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1q78a1_d1fa0b3__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; regulation of mRNA 3'-end processing [GO:0031440]; RNA polyadenylation [GO:0043631]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	mRNA polyadenylation [GO:0006378]; regulation of mRNA 3'-end processing [GO:0031440]; RNA polyadenylation [GO:0043631]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d1q78a1_d1sz1b1__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; regulation of mRNA 3'-end processing [GO:0031440]; RNA polyadenylation [GO:0043631]	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA polyadenylation [GO:0006378]; regulation of mRNA 3'-end processing [GO:0031440]; RNA polyadenylation [GO:0043631]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]
d1q79a1_d2drba1__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; regulation of mRNA 3'-end processing [GO:0031440]; RNA polyadenylation [GO:0043631]	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA polyadenylation [GO:0006378]; regulation of mRNA 3'-end processing [GO:0031440]; RNA polyadenylation [GO:0043631]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]
d1q7bc__d2iedb___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d1q7bd__d1vj0d2__1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d1q7cb__d4ei2j1__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]	potassium ion transport [GO:0006813]	cytosol [GO:0005829]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1q7gb2_d1e5qe2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; homoserine dehydrogenase activity [GO:0004412]; NADP binding [GO:0050661]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		homoserine dehydrogenase activity [GO:0004412]; NADP binding [GO:0050661]	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]
d1q7l.2_d2o53a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; aminoacylase activity [GO:0004046]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; cellular amino acid metabolic process [GO:0006520]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; nucleus [GO:0005634]; aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	cellular amino acid metabolic process [GO:0006520]; xenobiotic metabolic process [GO:0006805]	aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; nucleus [GO:0005634]	aminoacylase activity [GO:0004046]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]	aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1q7ma1_d2ycja1__1			Thermotogae	Firmicutes	cytosol [GO:0005829]; cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methionine synthase activity [GO:0008705]; pteridine-containing compound metabolic process [GO:0042558]	methyltransferase activity [GO:0008168]; pteridine-containing compound metabolic process [GO:0042558]	pteridine-containing compound metabolic process [GO:0042558]	pteridine-containing compound metabolic process [GO:0042558]	cytosol [GO:0005829]		cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methionine synthase activity [GO:0008705]	methyltransferase activity [GO:0008168]
d1q7sa__d1xtyc___1	Metazoa		Chordata	Crenarchaeota	cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; aminoacyl-tRNA hydrolase activity [GO:0004045]; apoptotic process [GO:0006915]; negative regulation of anoikis [GO:2000811]; negative regulation of gene expression [GO:0010629]; positive regulation of anoikis [GO:2000210]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	apoptotic process [GO:0006915]; negative regulation of anoikis [GO:2000811]; negative regulation of gene expression [GO:0010629]; positive regulation of anoikis [GO:2000210]	translation [GO:0006412]	cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	aminoacyl-tRNA hydrolase activity [GO:0004045]	aminoacyl-tRNA hydrolase activity [GO:0004045]
d1q7xa1_d2h3la2__1	Metazoa	Metazoa	Chordata	Chordata	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	basal plasma membrane [GO:0009925]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; hemidesmosome [GO:0030056]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ErbB-2 class receptor binding [GO:0005176]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]; basal protein localization [GO:0045175]; cell adhesion [GO:0007155]; cellular response to tumor necrosis factor [GO:0071356]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165]	cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	basal protein localization [GO:0045175]; cell adhesion [GO:0007155]; cellular response to tumor necrosis factor [GO:0071356]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	basal plasma membrane [GO:0009925]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; hemidesmosome [GO:0030056]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]	ErbB-2 class receptor binding [GO:0005176]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]
d1q7yc1_d1yi2a1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1q7yg1_d1yhqe2__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1q80a__d1cfda___1	Metazoa	Metazoa	Annelida	Chordata	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]		calcium-mediated signaling [GO:0019722]			calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]
d1q81d__d4pc1b2__1			Euryarchaeota	Proteobacteria	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; translation elongation factor activity [GO:0003746]	translation [GO:0006412]		ribosome [GO:0005840]	cytoplasm [GO:0005737]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	translation elongation factor activity [GO:0003746]
d1q81e__d2zjrc1__1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	cytosolic large ribosomal subunit [GO:0022625]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d1q81g1_d2qbig1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1q82e__d2hgjf1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1q82l__d2b9po1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1q82n__d2qa4m1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1q86c1_d2z4lc1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1q86h__d1yijf1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1q86q__d1vq9p1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1q8ka4_d3i4ob___1	Metazoa		Chordata	Actinobacteria	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 2 complex [GO:0005850]; eukaryotic translation initiation factor 2B complex [GO:0005851]; extracellular exosome [GO:0070062]; glial limiting end-foot [GO:0097451]; membrane [GO:0016020]; multi-eIF complex [GO:0043614]; nucleus [GO:0005634]; polysome [GO:0005844]; synapse [GO:0045202]; translation initiation ternary complex [GO:0044207]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743]; aging [GO:0007568]; cellular response to amino acid starvation [GO:0034198]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of translational initiation in response to stress [GO:0032057]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of neuron death [GO:1901216]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; protein autophosphorylation [GO:0046777]; response to endoplasmic reticulum stress [GO:0034976]; response to manganese-induced endoplasmic reticulum stress [GO:1990737]; stress granule assembly [GO:0034063]; translational initiation [GO:0006413]; transmembrane transport [GO:0055085]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation initiation factor activity [GO:0003743]	aging [GO:0007568]; cellular response to amino acid starvation [GO:0034198]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of translational initiation in response to stress [GO:0032057]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of neuron death [GO:1901216]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; protein autophosphorylation [GO:0046777]; response to endoplasmic reticulum stress [GO:0034976]; response to manganese-induced endoplasmic reticulum stress [GO:1990737]; stress granule assembly [GO:0034063]; translational initiation [GO:0006413]; transmembrane transport [GO:0055085]		cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 2B complex [GO:0005851]; eukaryotic translation initiation factor 2 complex [GO:0005850]; extracellular exosome [GO:0070062]; glial limiting end-foot [GO:0097451]; membrane [GO:0016020]; multi-eIF complex [GO:0043614]; nucleus [GO:0005634]; polysome [GO:0005844]; synapse [GO:0045202]; translation initiation ternary complex [GO:0044207]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	ribosome binding [GO:0043022]; RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743]	ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation initiation factor activity [GO:0003743]
d1q8la1_d2roea___1	Metazoa		Chordata	Deinococcus-Thermus	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]; antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	metal ion binding [GO:0046872]; metal ion transport [GO:0030001]	antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	metal ion transport [GO:0030001]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]	metal ion binding [GO:0046872]
d1q8mb1_d1ghfl1__1	Metazoa		Chordata		extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]; acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]		acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]	
d1q8mc1_d2gsig1__1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]; acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; membrane [GO:0016020]	scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1q8md1_d2ybra___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]; acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]	extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]	acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]	defense response [GO:0006952]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]	sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]
d1q8qa__d3d5od___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1q8qb__d2d3rc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1q8sa__d1nxd1___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1q8sa__d2yy1a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]
d1q8sb__d2zgua___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]		apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d1q8va__d2a3wt___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1q91a__d2jaua___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]
d1q91a__d5ai6a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d1q94a1_d4f57l1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1q94b1_d2nxzd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1q94d1_d1za6f1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1q94e1_d5xqyf___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1q95a1_d4h31a2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1q95c1_d3m5da1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]
d1q95c2_d4jfrb1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1q95d1_d1ortb1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1q95d2_d3m4ja1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]
d1q95f2_d8atca1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1q95g1_d1nbed1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1q97b__d2owba___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleus [GO:0005634]; ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; cellular cation homeostasis [GO:0030003]; cellular ion homeostasis [GO:0006873]; intracellular signal transduction [GO:0035556]; mRNA splice site selection [GO:0006376]; positive regulation of protein import into nucleus [GO:0042307]; protein phosphorylation [GO:0006468]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of mRNA processing [GO:0050684]; response to drug [GO:0042493]; spliceosomal complex assembly [GO:0000245]; stress granule disassembly [GO:0035617]	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]; anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	cellular cation homeostasis [GO:0030003]; cellular ion homeostasis [GO:0006873]; intracellular signal transduction [GO:0035556]; mRNA splice site selection [GO:0006376]; positive regulation of protein import into nucleus [GO:0042307]; protein phosphorylation [GO:0006468]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of mRNA processing [GO:0050684]; response to drug [GO:0042493]; spliceosomal complex assembly [GO:0000245]; stress granule disassembly [GO:0035617]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleus [GO:0005634]	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]
d1q98a__d2f8ab___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; SH3 domain binding [GO:0017124]; angiogenesis involved in wound healing [GO:0060055]; blood vessel endothelial cell migration [GO:0043534]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; endothelial cell development [GO:0001885]; fat cell differentiation [GO:0045444]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide catabolic process [GO:0042744]; interaction with symbiont [GO:0051702]; lipoxygenase pathway [GO:0019372]; myoblast proliferation [GO:0051450]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of supramolecular fiber organization [GO:1902905]; protein oxidation [GO:0018158]; purine nucleotide catabolic process [GO:0006195]; regulation of gene expression, epigenetic [GO:0040029]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of proteasomal protein catabolic process [GO:0061136]; response to gamma radiation [GO:0010332]; response to hydrogen peroxide [GO:0042542]; response to hydroperoxide [GO:0033194]; response to selenium ion [GO:0010269]; response to symbiotic bacterium [GO:0009609]; response to xenobiotic stimulus [GO:0009410]; sensory perception of sound [GO:0007605]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue regeneration [GO:0043403]; temperature homeostasis [GO:0001659]; triglyceride metabolic process [GO:0006641]; UV protection [GO:0009650]; vasodilation [GO:0042311]	cell redox homeostasis [GO:0045454]	angiogenesis involved in wound healing [GO:0060055]; blood vessel endothelial cell migration [GO:0043534]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; endothelial cell development [GO:0001885]; fat cell differentiation [GO:0045444]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide catabolic process [GO:0042744]; interaction with symbiont [GO:0051702]; lipoxygenase pathway [GO:0019372]; myoblast proliferation [GO:0051450]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of supramolecular fiber organization [GO:1902905]; protein oxidation [GO:0018158]; purine nucleotide catabolic process [GO:0006195]; regulation of gene expression, epigenetic [GO:0040029]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of proteasomal protein catabolic process [GO:0061136]; response to gamma radiation [GO:0010332]; response to hydrogen peroxide [GO:0042542]; response to hydroperoxide [GO:0033194]; response to selenium ion [GO:0010269]; response to symbiotic bacterium [GO:0009609]; response to xenobiotic stimulus [GO:0009410]; sensory perception of sound [GO:0007605]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue regeneration [GO:0043403]; temperature homeostasis [GO:0001659]; triglyceride metabolic process [GO:0006641]; UV protection [GO:0009650]; vasodilation [GO:0042311]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	thioredoxin peroxidase activity [GO:0008379]	glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; SH3 domain binding [GO:0017124]
d1q9eb__d3whoc___1	Fungi	Fungi	Ascomycota	Basidiomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]		endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1q9jb2_d1l5ac2__1			Actinobacteria	Proteobacteria	O-acyltransferase activity [GO:0008374]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; DIM/DIP cell wall layer assembly [GO:0071770]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; enterobactin synthetase complex [GO:0009366]; 2,3-dihydroxybenzoate-serine ligase activity [GO:0047527]; acid-ammonia (or amide) ligase activity [GO:0016880]; phosphopantetheine binding [GO:0031177]; amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; enterobactin biosynthetic process [GO:0009239]; secondary metabolite biosynthetic process [GO:0044550]; siderophore biosynthetic process [GO:0019290]	DIM/DIP cell wall layer assembly [GO:0071770]; lipid biosynthetic process [GO:0008610]	amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; enterobactin biosynthetic process [GO:0009239]; secondary metabolite biosynthetic process [GO:0044550]; siderophore biosynthetic process [GO:0019290]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; enterobactin synthetase complex [GO:0009366]	O-acyltransferase activity [GO:0008374]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	2,3-dihydroxybenzoate-serine ligase activity [GO:0047527]; acid-ammonia (or amide) ligase activity [GO:0016880]; phosphopantetheine binding [GO:0031177]
d1q9ka1_d5f8qc1__1				Proteobacteria								
d1q9kb1_d3stza1__1				Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1q9kb2_d5k8al1__1												
d1q9la1_d1ymmd1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1q9la2_d1g9mc1__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1q9lb2_d1cs6a3__1		Metazoa		Chordata		anchored component of membrane [GO:0031225]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; neuron cell-cell adhesion [GO:0007158]; presynaptic membrane organization [GO:0097090]		neuron cell-cell adhesion [GO:0007158]; presynaptic membrane organization [GO:0097090]		anchored component of membrane [GO:0031225]; plasma membrane [GO:0005886]		cell adhesion molecule binding [GO:0050839]
d1q9lc1_d1dzba2__1		Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; extracellular space [GO:0005615]		glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1q9lc1_d3vxtc2__1												
d1q9lc2_d5niva1__1												
d1q9ld1_d1mj7l1__1												
d1q9ld2_d4kxzm1__1		Metazoa		Chordata		axon [GO:0030424]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; platelet alpha granule lumen [GO:0031093]; amyloid-beta binding [GO:0001540]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; ascending aorta morphogenesis [GO:0035910]; atrial septum morphogenesis [GO:0060413]; atrial septum primum morphogenesis [GO:0003289]; atrioventricular valve morphogenesis [GO:0003181]; BMP signaling pathway [GO:0030509]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac muscle cell proliferation [GO:0060038]; cardiac right ventricle morphogenesis [GO:0003215]; cardioblast differentiation [GO:0010002]; cell cycle arrest [GO:0007050]; cell death [GO:0008219]; cell development [GO:0048468]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cell-cell junction organization [GO:0045216]; collagen fibril organization [GO:0030199]; cranial skeletal system development [GO:1904888]; dopamine biosynthetic process [GO:0042416]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic digestive tract development [GO:0048566]; embryonic limb morphogenesis [GO:0030326]; endocardial cushion fusion [GO:0003274]; endocardial cushion morphogenesis [GO:0003203]; epithelial to mesenchymal transition [GO:0001837]; extrinsic apoptotic signaling pathway [GO:0097191]; eye development [GO:0001654]; generation of neurons [GO:0048699]; glial cell migration [GO:0008347]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; hemopoiesis [GO:0030097]; inner ear development [GO:0048839]; kidney development [GO:0001822]; male gonad development [GO:0008584]; membranous septum morphogenesis [GO:0003149]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905006]; negative regulation of gene expression [GO:0010629]; negative regulation of immune response [GO:0050777]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of Ras protein signal transduction [GO:0046580]; neural retina development [GO:0003407]; neural tube closure [GO:0001843]; neuron development [GO:0048666]; neutrophil chemotaxis [GO:0030593]; odontogenesis [GO:0042476]; outflow tract septum morphogenesis [GO:0003148]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; pharyngeal arch artery morphogenesis [GO:0061626]; platelet degranulation [GO:0002576]; positive regulation of cardioblast differentiation [GO:0051891]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of heart contraction [GO:0045823]; positive regulation of immune response [GO:0050778]; positive regulation of integrin biosynthetic process [GO:0045726]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of ossification [GO:0045778]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of protein secretion [GO:0050714]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of timing of catagen [GO:0051795]; protein phosphorylation [GO:0006468]; pulmonary valve morphogenesis [GO:0003184]; regulation of apoptotic process [GO:0042981]; regulation of apoptotic process involved in outflow tract morphogenesis [GO:1902256]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; regulation of timing of catagen [GO:0051794]; regulation of transforming growth factor beta2 production [GO:0032909]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395]; somatic stem cell division [GO:0048103]; substantia propria of cornea development [GO:1903701]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060]		activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; ascending aorta morphogenesis [GO:0035910]; atrial septum morphogenesis [GO:0060413]; atrial septum primum morphogenesis [GO:0003289]; atrioventricular valve morphogenesis [GO:0003181]; BMP signaling pathway [GO:0030509]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac muscle cell proliferation [GO:0060038]; cardiac right ventricle morphogenesis [GO:0003215]; cardioblast differentiation [GO:0010002]; cell-cell junction organization [GO:0045216]; cell cycle arrest [GO:0007050]; cell death [GO:0008219]; cell development [GO:0048468]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; collagen fibril organization [GO:0030199]; cranial skeletal system development [GO:1904888]; dopamine biosynthetic process [GO:0042416]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic digestive tract development [GO:0048566]; embryonic limb morphogenesis [GO:0030326]; endocardial cushion fusion [GO:0003274]; endocardial cushion morphogenesis [GO:0003203]; epithelial to mesenchymal transition [GO:0001837]; extrinsic apoptotic signaling pathway [GO:0097191]; eye development [GO:0001654]; generation of neurons [GO:0048699]; glial cell migration [GO:0008347]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; hemopoiesis [GO:0030097]; inner ear development [GO:0048839]; kidney development [GO:0001822]; male gonad development [GO:0008584]; membranous septum morphogenesis [GO:0003149]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905006]; negative regulation of gene expression [GO:0010629]; negative regulation of immune response [GO:0050777]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of Ras protein signal transduction [GO:0046580]; neural retina development [GO:0003407]; neural tube closure [GO:0001843]; neuron development [GO:0048666]; neutrophil chemotaxis [GO:0030593]; odontogenesis [GO:0042476]; outflow tract septum morphogenesis [GO:0003148]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; pharyngeal arch artery morphogenesis [GO:0061626]; platelet degranulation [GO:0002576]; positive regulation of cardioblast differentiation [GO:0051891]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of heart contraction [GO:0045823]; positive regulation of immune response [GO:0050778]; positive regulation of integrin biosynthetic process [GO:0045726]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of ossification [GO:0045778]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of protein secretion [GO:0050714]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of timing of catagen [GO:0051795]; protein phosphorylation [GO:0006468]; pulmonary valve morphogenesis [GO:0003184]; regulation of apoptotic process [GO:0042981]; regulation of apoptotic process involved in outflow tract morphogenesis [GO:1902256]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; regulation of timing of catagen [GO:0051794]; regulation of transforming growth factor beta2 production [GO:0032909]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395]; somatic stem cell division [GO:0048103]; substantia propria of cornea development [GO:1903701]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060]		axon [GO:0030424]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; platelet alpha granule lumen [GO:0031093]		amyloid-beta binding [GO:0001540]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]
d1q9mb__d3qpoa___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]
d1q9mc__d5g57a___1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	axoneme [GO:0005930]; cytoplasm [GO:0005737]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; cell morphogenesis [GO:0000902]; signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cell morphogenesis [GO:0000902]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	axoneme [GO:0005930]; cytoplasm [GO:0005737]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]
d1q9oa1_d1nj9a1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1q9oa2_d3rpib2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1q9ob2_d4hfwa2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1q9od1_d5nmda2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1q9od2_d2r56m1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1q9ra4_d2bveb___1		Metazoa		Chordata		extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]		cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]		extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]
d1q9rb3_d3nidl1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1q9rb4_d2yz1b___1		Metazoa		Chordata		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]; actin filament organization [GO:0007015]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; cytoskeleton organization [GO:0007010]; granulocyte migration [GO:0097530]; hematopoietic progenitor cell differentiation [GO:0002244]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]		actin filament organization [GO:0007015]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; cytoskeleton organization [GO:0007010]; granulocyte migration [GO:0097530]; hematopoietic progenitor cell differentiation [GO:0002244]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]
d1q9rb4_d4f58m2__1												
d1q9tb4_d4grwh___1		Metazoa		Chordata		cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]; cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]		cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]		cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]		cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d1q9va3_d4z5rp2__1		Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]		adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]		collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]
d1q9va4_d3o3db1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1q9vb3_d1g9nh2__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1q9wa1_d5cfha___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1q9wa2_d1gpoh2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1q9wb2_d1mjul1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1q9wc1_d4u0qb2__1	Metazoa		Chordata	Apicomplexa	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1q9wc1_d5kvgl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1q9wc2_d2nw3a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1q9wd2_d5c0rl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; entry into host cell [GO:0030260]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; entry into host cell [GO:0030260]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1q9xa1_d1kvca___1				Proteobacteria	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]		cytoplasm [GO:0005737]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1qa0a__d5c2zb___1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d1qa7a__d5e0ja1__1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]
d1qa7b__d1uj1b___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1qa7d__d2bohb___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1qabb__d3kgua___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1qabc__d1iikb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1qabd__d3iwva___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1qabd__d5e4ab___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1qabe__d1n0sa___1	Metazoa	Metazoa	Chordata	Arthropoda	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	extracellular region [GO:0005576]; pigment binding [GO:0031409]; protein-chromophore linkage [GO:0018298]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	protein-chromophore linkage [GO:0018298]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	pigment binding [GO:0031409]
d1qabe__d5n4pa1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]; cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]; membrane organization [GO:0061024]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	membrane organization [GO:0061024]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]
d1qaca__d1blnc1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]	
d1qacb__d3mckl2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]	
d1qafb2_d2e2ua2__1			Proteobacteria	Actinobacteria	periplasmic space [GO:0042597]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	amine metabolic process [GO:0009308]	periplasmic space [GO:0042597]		aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d1qama__d5eiwc1__1			Firmicutes		23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity [GO:0052910]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]; response to antibiotic [GO:0046677]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	response to antibiotic [GO:0046677]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity [GO:0052910]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1qapa1_d1qpoc1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qapa1_d5huof2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qasa1_d3vgoa2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	cytosol [GO:0005829]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]; cell surface receptor signaling pathway [GO:0007166]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; NLS-bearing protein import into nucleus [GO:0006607]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; signal transduction [GO:0007165]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	cell surface receptor signaling pathway [GO:0007166]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; NLS-bearing protein import into nucleus [GO:0006607]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	cytosol [GO:0005829]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]	calcium ion binding [GO:0005509]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]
d1qasb1_d1la0a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	troponin complex [GO:0005861]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]
d1qaua__d4k6ya___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]; ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]	ion channel binding [GO:0044325]
d1qavb__d2h2ca1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystrophin-associated glycoprotein complex [GO:0016010]; neuromuscular junction [GO:0031594]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; calmodulin binding [GO:0005516]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; PDZ domain binding [GO:0030165]; structural molecule activity [GO:0005198]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; neuromuscular junction development [GO:0007528]; regulation of heart rate [GO:0002027]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of vasoconstriction by circulating norepinephrine [GO:0003117]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; ventricular cardiac muscle cell action potential [GO:0086005]	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell projection [GO:0042995]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; neuromuscular junction development [GO:0007528]; regulation of heart rate [GO:0002027]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of vasoconstriction by circulating norepinephrine [GO:0003117]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; ventricular cardiac muscle cell action potential [GO:0086005]	adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of cell migration [GO:0030335]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystrophin-associated glycoprotein complex [GO:0016010]; neuromuscular junction [GO:0031594]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; calmodulin binding [GO:0005516]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; PDZ domain binding [GO:0030165]; structural molecule activity [GO:0005198]	cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]
d1qb5e__d1cqfa___1			Proteobacteria		extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1qb5g__d1ltbf___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]		killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1qbaa1_d1uh4a1__1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	periplasmic space [GO:0042597]	extracellular region [GO:0005576]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1qbaa1_d5e6zb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	periplasmic space [GO:0042597]	cytosol [GO:0005829]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1qbaa3_d1zjbb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	periplasmic space [GO:0042597]		beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d1qbba2_d3l8qc1__1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	periplasmic space [GO:0042597]		beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1qbba3_d4im4b___1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; acetylxylan esterase activity [GO:0046555]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; glucomannan catabolic process [GO:2000884]; xylan catabolic process [GO:0045493]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]; glucomannan catabolic process [GO:2000884]; xylan catabolic process [GO:0045493]	periplasmic space [GO:0042597]	extracellular region [GO:0005576]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]	acetylxylan esterase activity [GO:0046555]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d1qbga__d3f6rd___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1qbgc__d1fuea___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	FMN binding [GO:0010181]; oxidation-reduction process [GO:0055114]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	FMN binding [GO:0010181]
d1qbgc__d2qx8a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1qblh2_d4nqee1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1qbll1_d2ig2l2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1qbll2_d1k6qh1__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1qbmh1_d3qhzm1__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1qbmh1_d4eigb1__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d1qbmh2_d1frgl1__1	Metazoa		Chordata	Negarnaviricota	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d1qbml1_d5dq9b1__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1qbml1_d5k9jl1__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1qbtb__d5p28a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	aspartic-type endopeptidase activity [GO:0004190]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1qbv.1_d3v7ta___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1qc5b__d2i91a2__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; integrin complex [GO:0008305]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell-matrix adhesion [GO:0007160]; cellular extravasation [GO:0045123]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; muscle contraction [GO:0006936]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; misfolded RNA binding [GO:0034336]; cell projection organization [GO:0030030]	activation of MAPK activity [GO:0000187]; cell-matrix adhesion [GO:0007160]; cellular extravasation [GO:0045123]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; muscle contraction [GO:0006936]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	cell projection organization [GO:0030030]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; integrin complex [GO:0008305]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]	metal ion binding [GO:0046872]; misfolded RNA binding [GO:0034336]
d1qc7a__d3pl4b1__1			Thermotogae		bacterial-type flagellum basal body [GO:0009425]; plasma membrane [GO:0005886]; motor activity [GO:0003774]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]		bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]		bacterial-type flagellum basal body [GO:0009425]; plasma membrane [GO:0005886]		motor activity [GO:0003774]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	
d1qcbd__d1b1zc1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1qcbd__d1bcpi1__1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1qcga__d4lroa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1qcib__d4lhqc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		endoplasmic reticulum [GO:0005783]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1qcoa2_d5d2fa___1	Metazoa		Chordata	Proteobacteria	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]; arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]				fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1qcra1_d1pp9n2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1qcrb1_d1hr9h1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]; aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]
d1qcrb1_d3l70n1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1qd0a1_d1g7ha___1	Metazoa	Metazoa	Chordata	Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1qd0a1_d2jccm2__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1qd9b__d5v4dd1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; deaminase activity [GO:0019239]; 2-oxobutyrate biosynthetic process [GO:0046360]; isoleucine biosynthetic process [GO:0009097]; response to toxic substance [GO:0009636]	metal ion binding [GO:0046872]	2-oxobutyrate biosynthetic process [GO:0046360]; isoleucine biosynthetic process [GO:0009097]; response to toxic substance [GO:0009636]		cytoplasm [GO:0005737]		deaminase activity [GO:0019239]	metal ion binding [GO:0046872]
d1qd9c__d3mqwe1__1			Firmicutes		cytoplasm [GO:0005737]; deaminase activity [GO:0019239]; 2-oxobutyrate biosynthetic process [GO:0046360]; isoleucine biosynthetic process [GO:0009097]; response to toxic substance [GO:0009636]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	2-oxobutyrate biosynthetic process [GO:0046360]; isoleucine biosynthetic process [GO:0009097]; response to toxic substance [GO:0009636]	organonitrogen compound catabolic process [GO:1901565]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	deaminase activity [GO:0019239]	deaminase activity [GO:0019239]
d1qdbb__d3torc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]; calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]; anaerobic electron transport chain [GO:0019645]; nitrate assimilation [GO:0042128]	nitrate assimilation [GO:0042128]	anaerobic electron transport chain [GO:0019645]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]	calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]
d1qdlb__d3b3aa1__1		Metazoa	Crenarchaeota	Chordata	anthranilate synthase activity [GO:0004049]; glutamine metabolic process [GO:0006541]; tryptophan biosynthetic process [GO:0000162]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	glutamine metabolic process [GO:0006541]; tryptophan biosynthetic process [GO:0000162]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]		axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]	anthranilate synthase activity [GO:0004049]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]
d1qdna1_d5ftkd1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; midbody [GO:0030496]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of receptor recycling [GO:0001921]; potassium ion transport [GO:0006813]; SNARE complex disassembly [GO:0035494]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of receptor recycling [GO:0001921]; potassium ion transport [GO:0006813]; SNARE complex disassembly [GO:0035494]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	cytosol [GO:0005829]; midbody [GO:0030496]; plasma membrane [GO:0005886]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1qdnc1_d2v3va1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; midbody [GO:0030496]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of receptor recycling [GO:0001921]; potassium ion transport [GO:0006813]; SNARE complex disassembly [GO:0035494]	periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of receptor recycling [GO:0001921]; potassium ion transport [GO:0006813]; SNARE complex disassembly [GO:0035494]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	cytosol [GO:0005829]; midbody [GO:0030496]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]
d1qdoa__d1ww5d___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]		apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d1qdob__d2phrb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1qdod__d1fatb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; toxin activity [GO:0090729]; defense response [GO:0006952]		defense response [GO:0006952]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; toxin activity [GO:0090729]
d1qdod__d1gykd___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1qdu.1_d1i3o.1__1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ripoptosome [GO:0097342]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type peptidase activity [GO:0008234]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; death-inducing signaling complex assembly [GO:0071550]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macrophage differentiation [GO:0030225]; natural killer cell activation [GO:0030101]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of proteolysis [GO:0045862]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of necroptotic process [GO:0060544]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039650]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell activation [GO:0042110]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; aspartic-type endopeptidase activity [GO:0004190]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; death receptor binding [GO:0005123]; peptidase activity [GO:0008233]; phospholipase A2 activator activity [GO:0016005]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; anterior neural tube closure [GO:0061713]; apoptotic DNA fragmentation [GO:0006309]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; axonal fasciculation [GO:0007413]; B cell homeostasis [GO:0001782]; cell fate commitment [GO:0045165]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to staurosporine [GO:0072734]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte differentiation [GO:0030218]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glial cell apoptotic process [GO:0034349]; heart development [GO:0007507]; hippo signaling [GO:0035329]; hippocampus development [GO:0021766]; intrinsic apoptotic signaling pathway in response to osmotic stress [GO:0008627]; keratinocyte differentiation [GO:0030216]; learning or memory [GO:0007611]; leukocyte apoptotic process [GO:0071887]; luteolysis [GO:0001554]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell proliferation [GO:0030889]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet formation [GO:0030220]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of neuron apoptotic process [GO:0043525]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647]; response to amino acid [GO:0043200]; response to cobalt ion [GO:0032025]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; sensory perception of sound [GO:0007605]; striated muscle cell differentiation [GO:0051146]; T cell homeostasis [GO:0043029]; wound healing [GO:0042060]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; death-inducing signaling complex assembly [GO:0071550]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macrophage differentiation [GO:0030225]; natural killer cell activation [GO:0030101]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of proteolysis [GO:0045862]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of necroptotic process [GO:0060544]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039650]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell activation [GO:0042110]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]	anterior neural tube closure [GO:0061713]; apoptotic DNA fragmentation [GO:0006309]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; axonal fasciculation [GO:0007413]; B cell homeostasis [GO:0001782]; cell fate commitment [GO:0045165]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to staurosporine [GO:0072734]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte differentiation [GO:0030218]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glial cell apoptotic process [GO:0034349]; heart development [GO:0007507]; hippocampus development [GO:0021766]; hippo signaling [GO:0035329]; intrinsic apoptotic signaling pathway in response to osmotic stress [GO:0008627]; keratinocyte differentiation [GO:0030216]; learning or memory [GO:0007611]; leukocyte apoptotic process [GO:0071887]; luteolysis [GO:0001554]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell proliferation [GO:0030889]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet formation [GO:0030220]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of neuron apoptotic process [GO:0043525]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647]; response to amino acid [GO:0043200]; response to cobalt ion [GO:0032025]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; sensory perception of sound [GO:0007605]; striated muscle cell differentiation [GO:0051146]; T cell homeostasis [GO:0043029]; wound healing [GO:0042060]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ripoptosome [GO:0097342]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type peptidase activity [GO:0008234]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]	aspartic-type endopeptidase activity [GO:0004190]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; death receptor binding [GO:0005123]; peptidase activity [GO:0008233]; phospholipase A2 activator activity [GO:0016005]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]
d1qdu.3_d1re1.1__1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ripoptosome [GO:0097342]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type peptidase activity [GO:0008234]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; death-inducing signaling complex assembly [GO:0071550]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macrophage differentiation [GO:0030225]; natural killer cell activation [GO:0030101]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of proteolysis [GO:0045862]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of necroptotic process [GO:0060544]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039650]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell activation [GO:0042110]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; aspartic-type endopeptidase activity [GO:0004190]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; death receptor binding [GO:0005123]; peptidase activity [GO:0008233]; phospholipase A2 activator activity [GO:0016005]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; anterior neural tube closure [GO:0061713]; apoptotic DNA fragmentation [GO:0006309]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; axonal fasciculation [GO:0007413]; B cell homeostasis [GO:0001782]; cell fate commitment [GO:0045165]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to staurosporine [GO:0072734]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte differentiation [GO:0030218]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glial cell apoptotic process [GO:0034349]; heart development [GO:0007507]; hippo signaling [GO:0035329]; hippocampus development [GO:0021766]; intrinsic apoptotic signaling pathway in response to osmotic stress [GO:0008627]; keratinocyte differentiation [GO:0030216]; learning or memory [GO:0007611]; leukocyte apoptotic process [GO:0071887]; luteolysis [GO:0001554]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell proliferation [GO:0030889]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet formation [GO:0030220]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of neuron apoptotic process [GO:0043525]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647]; response to amino acid [GO:0043200]; response to cobalt ion [GO:0032025]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; sensory perception of sound [GO:0007605]; striated muscle cell differentiation [GO:0051146]; T cell homeostasis [GO:0043029]; wound healing [GO:0042060]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; death-inducing signaling complex assembly [GO:0071550]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macrophage differentiation [GO:0030225]; natural killer cell activation [GO:0030101]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of proteolysis [GO:0045862]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of necroptotic process [GO:0060544]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039650]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell activation [GO:0042110]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]	anterior neural tube closure [GO:0061713]; apoptotic DNA fragmentation [GO:0006309]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; axonal fasciculation [GO:0007413]; B cell homeostasis [GO:0001782]; cell fate commitment [GO:0045165]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to staurosporine [GO:0072734]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte differentiation [GO:0030218]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glial cell apoptotic process [GO:0034349]; heart development [GO:0007507]; hippocampus development [GO:0021766]; hippo signaling [GO:0035329]; intrinsic apoptotic signaling pathway in response to osmotic stress [GO:0008627]; keratinocyte differentiation [GO:0030216]; learning or memory [GO:0007611]; leukocyte apoptotic process [GO:0071887]; luteolysis [GO:0001554]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell proliferation [GO:0030889]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet formation [GO:0030220]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of neuron apoptotic process [GO:0043525]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647]; response to amino acid [GO:0043200]; response to cobalt ion [GO:0032025]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; sensory perception of sound [GO:0007605]; striated muscle cell differentiation [GO:0051146]; T cell homeostasis [GO:0043029]; wound healing [GO:0042060]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ripoptosome [GO:0097342]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type peptidase activity [GO:0008234]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]	aspartic-type endopeptidase activity [GO:0004190]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; death receptor binding [GO:0005123]; peptidase activity [GO:0008233]; phospholipase A2 activator activity [GO:0016005]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]
d1qdvc__d1dsxd___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]
d1qdwg__d1eoda___1	Metazoa	Metazoa	Chordata	Mollusca	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	voltage-gated potassium channel complex [GO:0008076]; voltage-gated potassium channel activity [GO:0005249]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	voltage-gated potassium channel complex [GO:0008076]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]	voltage-gated potassium channel activity [GO:0005249]
d1qe6a__d1rhpc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; chemokine activity [GO:0008009]; interleukin-8 receptor binding [GO:0005153]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; calcium-mediated signaling [GO:0019722]; cell cycle arrest [GO:0007050]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; embryonic digestive tract development [GO:0048566]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of angiogenesis [GO:0045766]; positive regulation of neutrophil chemotaxis [GO:0090023]; receptor internalization [GO:0031623]; regulation of cell adhesion [GO:0030155]; regulation of entry of bacterium into host cell [GO:2000535]; regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045091]; response to endoplasmic reticulum stress [GO:0034976]; response to molecule of bacterial origin [GO:0002237]; signal transduction [GO:0007165]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]; chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; calcium-mediated signaling [GO:0019722]; cell cycle arrest [GO:0007050]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; embryonic digestive tract development [GO:0048566]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of angiogenesis [GO:0045766]; positive regulation of neutrophil chemotaxis [GO:0090023]; receptor internalization [GO:0031623]; regulation of cell adhesion [GO:0030155]; regulation of entry of bacterium into host cell [GO:2000535]; regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045091]; response to endoplasmic reticulum stress [GO:0034976]; response to molecule of bacterial origin [GO:0002237]; signal transduction [GO:0007165]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]	chemokine activity [GO:0008009]; interleukin-8 receptor binding [GO:0005153]	chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]
d1qewa2_d3wexg1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1qewb1_d5vxjf___1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	pathogenesis [GO:0009405]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1qezc__d2bqxa___1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1qezc__d3q5va___1			Crenarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1qeze__d4qlzb___1		Metazoa	Crenarchaeota	Platyhelminthes	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1qf2a__d5l8pe___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1qf3a__d1hkd.1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1qf3b__d2voka1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; cell cycle [GO:0007049]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein deubiquitination [GO:0090086]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of autophagy [GO:0010508]; positive regulation of cell cycle [GO:0045787]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein trimerization [GO:0070206]; protein ubiquitination [GO:0016567]; response to interferon-gamma [GO:0034341]		cell cycle [GO:0007049]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein deubiquitination [GO:0090086]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of autophagy [GO:0010508]; positive regulation of cell cycle [GO:0045787]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein trimerization [GO:0070206]; protein ubiquitination [GO:0016567]; response to interferon-gamma [GO:0034341]		autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1qf3c__d1wbla___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1qf4a__d1dj2b___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; 'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; plastid [GO:0009536]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; 'de novo' AMP biosynthetic process [GO:0044208]; IMP metabolic process [GO:0046040]; response to cadmium ion [GO:0046686]	'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' AMP biosynthetic process [GO:0044208]; IMP metabolic process [GO:0046040]; response to cadmium ion [GO:0046686]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; plastid [GO:0009536]	adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d1qf6a2_d5ee1a2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of response to salt stress [GO:1901001]; response to cadmium ion [GO:0046686]; response to salt stress [GO:0009651]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	negative regulation of defense response to bacterium [GO:1900425]; negative regulation of response to salt stress [GO:1901001]; response to cadmium ion [GO:0046686]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]
d1qf7a1_d2nv2x___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]; glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d1qfeb__d1w3ta___1			Proteobacteria	Crenarchaeota	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	carbohydrate metabolic process [GO:0005975]			3-dehydroquinate dehydratase activity [GO:0003855]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]
d1qfeb__d3eb2a___1			Proteobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	lyase activity [GO:0016829]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]				3-dehydroquinate dehydratase activity [GO:0003855]	lyase activity [GO:0016829]
d1qfhb1_d2w0pa___1		Metazoa		Chordata	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]; actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]; actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d1qfja2_d3ozvb3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; enzyme activator activity [GO:0008047]; riboflavin reductase (NADH) activity [GO:0052875]; riboflavin reductase (NADPH) activity [GO:0042602]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	enzyme activator activity [GO:0008047]; riboflavin reductase (NADH) activity [GO:0052875]; riboflavin reductase (NADPH) activity [GO:0042602]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1qfjb2_d4yaob3__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; enzyme activator activity [GO:0008047]; riboflavin reductase (NADH) activity [GO:0052875]; riboflavin reductase (NADPH) activity [GO:0042602]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cytosol [GO:0005829]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	enzyme activator activity [GO:0008047]; riboflavin reductase (NADH) activity [GO:0052875]; riboflavin reductase (NADPH) activity [GO:0042602]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1qfjc2_d3w2ea2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; enzyme activator activity [GO:0008047]; riboflavin reductase (NADH) activity [GO:0052875]; riboflavin reductase (NADPH) activity [GO:0042602]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cholesterol biosynthetic process [GO:0006695]	cytosol [GO:0005829]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	enzyme activator activity [GO:0008047]; riboflavin reductase (NADH) activity [GO:0052875]; riboflavin reductase (NADPH) activity [GO:0042602]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1qfla2_d5wx5f1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1qflb2_d4ubvb1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d1qfna__d5hr1b___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; electron transfer activity [GO:0009055]; nucleotide binding [GO:0000166]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	electron transfer activity [GO:0009055]; nucleotide binding [GO:0000166]; protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1qfra__d5t1na___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; transferase activity, transferring phosphorus-containing groups [GO:0016772]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; protein phosphorylation [GO:0006468]; response to organonitrogen compound [GO:0010243]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; protein phosphorylation [GO:0006468]; response to organonitrogen compound [GO:0010243]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]		transferase activity, transferring phosphorus-containing groups [GO:0016772]
d1qfsa1_d4re6c1__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type peptidase activity [GO:0008236]
d1qfsa2_d1h2ya2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d1qfta__d3pp6c___1	Metazoa	Metazoa	Arthropoda	Mollusca	extracellular region [GO:0005576]; amine binding [GO:0043176]; evasion or tolerance of host defense response [GO:0030682]	cytoplasm [GO:0005737]; membrane [GO:0016020]; lipid binding [GO:0008289]	evasion or tolerance of host defense response [GO:0030682]		extracellular region [GO:0005576]	cytoplasm [GO:0005737]; membrane [GO:0016020]	amine binding [GO:0043176]	lipid binding [GO:0008289]
d1qftb__d4zj0a___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; amine binding [GO:0043176]; evasion or tolerance of host defense response [GO:0030682]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	evasion or tolerance of host defense response [GO:0030682]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]	amine binding [GO:0043176]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1qfua__d5br3c___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1qfuh1_d1bvlb___1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d1qfuh1_d5jr1l2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d1qfvb__d4orya___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; amine binding [GO:0043176]; evasion or tolerance of host defense response [GO:0030682]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	evasion or tolerance of host defense response [GO:0030682]	cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	extracellular region [GO:0005576]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	amine binding [GO:0043176]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d1qfwi1_d3nn8b___1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1qfwm__d1zlsl2__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]			
d1qfya1_d1krha1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]; toluene catabolic process [GO:0042203]	photosynthesis [GO:0015979]	toluene catabolic process [GO:0042203]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]		ferredoxin-NADP+ reductase activity [GO:0004324]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]
d1qfyb1_d1kzla1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; nucleus [GO:0005634]; riboflavin synthase activity [GO:0004746]; riboflavin biosynthetic process [GO:0009231]	photosynthesis [GO:0015979]	riboflavin biosynthetic process [GO:0009231]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	cytosol [GO:0005829]; nucleus [GO:0005634]	ferredoxin-NADP+ reductase activity [GO:0004324]	riboflavin synthase activity [GO:0004746]
d1qfza1_d1tllb1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]; ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	photosynthesis [GO:0015979]	aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]	ferredoxin-NADP+ reductase activity [GO:0004324]	ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]
d1qfza2_d1qx4b2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; mitochondrial outer membrane [GO:0005741]; ADP binding [GO:0043531]; AMP binding [GO:0016208]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; cholesterol biosynthetic process [GO:0006695]	photosynthesis [GO:0015979]	cholesterol biosynthetic process [GO:0006695]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; mitochondrial outer membrane [GO:0005741]	ferredoxin-NADP+ reductase activity [GO:0004324]	ADP binding [GO:0043531]; AMP binding [GO:0016208]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]
d1qg0b2_d1ddgb2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	photosynthesis [GO:0015979]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]	ferredoxin-NADP+ reductase activity [GO:0004324]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]
d1qg0b2_d1qufa2__1	Viridiplantae		Streptophyta	Cyanobacteria	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d1qg3a2_d2ksxb2__1	Metazoa		Chordata		cell junction [GO:0030054]; cell leading edge [GO:0031252]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; hemidesmosome [GO:0030056]; integrin complex [GO:0008305]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; G protein-coupled receptor binding [GO:0001664]; integrin binding [GO:0005178]; amelogenesis [GO:0097186]; autophagy [GO:0006914]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell motility [GO:0048870]; cell-matrix adhesion [GO:0007160]; digestive tract development [GO:0048565]; extracellular matrix organization [GO:0030198]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; mesodermal cell differentiation [GO:0048333]; nail development [GO:0035878]; renal system development [GO:0072001]; response to wounding [GO:0009611]; skin development [GO:0043588]		amelogenesis [GO:0097186]; autophagy [GO:0006914]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell motility [GO:0048870]; digestive tract development [GO:0048565]; extracellular matrix organization [GO:0030198]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; mesodermal cell differentiation [GO:0048333]; nail development [GO:0035878]; renal system development [GO:0072001]; response to wounding [GO:0009611]; skin development [GO:0043588]		cell junction [GO:0030054]; cell leading edge [GO:0031252]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; hemidesmosome [GO:0030056]; integrin complex [GO:0008305]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		G protein-coupled receptor binding [GO:0001664]; integrin binding [GO:0005178]	
d1qg3b1_d1gh7a2__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cell leading edge [GO:0031252]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; hemidesmosome [GO:0030056]; integrin complex [GO:0008305]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; G protein-coupled receptor binding [GO:0001664]; integrin binding [GO:0005178]; amelogenesis [GO:0097186]; autophagy [GO:0006914]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell motility [GO:0048870]; cell-matrix adhesion [GO:0007160]; digestive tract development [GO:0048565]; extracellular matrix organization [GO:0030198]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; mesodermal cell differentiation [GO:0048333]; nail development [GO:0035878]; renal system development [GO:0072001]; response to wounding [GO:0009611]; skin development [GO:0043588]	granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; signaling receptor activity [GO:0038023]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-3 [GO:0036016]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-3-mediated signaling pathway [GO:0038156]; interleukin-5-mediated signaling pathway [GO:0038043]; MAPK cascade [GO:0000165]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]	amelogenesis [GO:0097186]; autophagy [GO:0006914]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell motility [GO:0048870]; digestive tract development [GO:0048565]; extracellular matrix organization [GO:0030198]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; mesodermal cell differentiation [GO:0048333]; nail development [GO:0035878]; renal system development [GO:0072001]; response to wounding [GO:0009611]; skin development [GO:0043588]	cellular protein metabolic process [GO:0044267]; cellular response to interleukin-3 [GO:0036016]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-3-mediated signaling pathway [GO:0038156]; interleukin-5-mediated signaling pathway [GO:0038043]; MAPK cascade [GO:0000165]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]	cell junction [GO:0030054]; cell leading edge [GO:0031252]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; hemidesmosome [GO:0030056]; integrin complex [GO:0008305]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	G protein-coupled receptor binding [GO:0001664]; integrin binding [GO:0005178]	cytokine receptor activity [GO:0004896]; signaling receptor activity [GO:0038023]
d1qg4a__d2ofwe___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; melanosome [GO:0042470]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RISC complex [GO:0016442]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; nuclear export signal receptor activity [GO:0005049]; pre-miRNA binding [GO:0070883]; RISC complex binding [GO:1905172]; cell division [GO:0051301]; GTP metabolic process [GO:0046039]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of protein export from nucleus [GO:0046827]; pre-miRNA export from nucleus [GO:0035281]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cell division [GO:0051301]; GTP metabolic process [GO:0046039]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of protein export from nucleus [GO:0046827]; pre-miRNA export from nucleus [GO:0035281]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; melanosome [GO:0042470]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RISC complex [GO:0016442]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; nuclear export signal receptor activity [GO:0005049]; pre-miRNA binding [GO:0070883]; RISC complex binding [GO:1905172]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1qg4a__d5bwma___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; melanosome [GO:0042470]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RISC complex [GO:0016442]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; nuclear export signal receptor activity [GO:0005049]; pre-miRNA binding [GO:0070883]; RISC complex binding [GO:1905172]; cell division [GO:0051301]; GTP metabolic process [GO:0046039]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of protein export from nucleus [GO:0046827]; pre-miRNA export from nucleus [GO:0035281]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cell division [GO:0051301]; GTP metabolic process [GO:0046039]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of protein export from nucleus [GO:0046827]; pre-miRNA export from nucleus [GO:0035281]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; melanosome [GO:0042470]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RISC complex [GO:0016442]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; nuclear export signal receptor activity [GO:0005049]; pre-miRNA binding [GO:0070883]; RISC complex binding [GO:1905172]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d1qg6a__d4iivc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; nucleotide binding [GO:0000166]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]; membrane [GO:0016020]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; nucleotide binding [GO:0000166]
d1qgaa2_d3w5uc2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	photosynthesis [GO:0015979]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	chloroplast thylakoid membrane protein complex [GO:0098807]	ferredoxin-NADP+ reductase activity [GO:0004324]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d1qgab1_d1tlla1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]; ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	photosynthesis [GO:0015979]	aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]	ferredoxin-NADP+ reductase activity [GO:0004324]	ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]
d1qgdb2_d2wvaz1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]		manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1qgdb3_d3exfb2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1qgha__d1t0ra___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1qghb__d1z6or___1		Metazoa	Firmicutes	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1qghd__d1xmgb___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1qghg__d3olja1__1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1qghh__d5c6fb1__1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d1qghi__d3bvfb1__1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d1qghj__d1mmob___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1qghk__d1z6ou___1		Metazoa	Firmicutes	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1qghl__d3uoib___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1qgia__d4oltb___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; chitosanase activity [GO:0016977]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; chitosanase activity [GO:0016977]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	chitosanase activity [GO:0016977]	chitosanase activity [GO:0016977]
d1qgja__d1ddxc1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1qgka__d1m8yb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; RNA binding [GO:0003723]; DNA metabolic process [GO:0006259]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; modulation by virus of host cellular process [GO:0019054]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; regulation of DNA recombination [GO:0000018]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	DNA metabolic process [GO:0006259]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; modulation by virus of host cellular process [GO:0019054]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; regulation of DNA recombination [GO:0000018]	adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]	histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; RNA binding [GO:0003723]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]
d1qglb__d1bzwb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1qgnd__d1pg8d___1	Viridiplantae		Streptophyta	Proteobacteria	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	transsulfuration [GO:0019346]	transsulfuration [GO:0019346]			catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d1qgng__d5wyaa___1	Viridiplantae		Streptophyta	Firmicutes	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	isomerase activity [GO:0016853]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	transsulfuration [GO:0019346]				catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	isomerase activity [GO:0016853]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1qgng__d5x2wc___1	Viridiplantae		Streptophyta	Proteobacteria	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	transsulfuration [GO:0019346]	transsulfuration [GO:0019346]			catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d1qgtc__d4bmga___1					host cell cytoplasm [GO:0030430]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; DNA binding [GO:0003677]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; pathogenesis [GO:0009405]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	host cell cytoplasm [GO:0030430]; T=4 icosahedral viral capsid [GO:0039619]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; pathogenesis [GO:0009405]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; pathogenesis [GO:0009405]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; pathogenesis [GO:0009405]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	host cell cytoplasm [GO:0030430]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]	host cell cytoplasm [GO:0030430]; T=4 icosahedral viral capsid [GO:0039619]	DNA binding [GO:0003677]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1qguc__d1m34c___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1qgya1_d1fnca1__1		Viridiplantae	Cyanobacteria	Streptophyta	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	photosynthesis [GO:0015979]	phycobilisome [GO:0030089]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]
d1qgya2_d4yaub3__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	phycobilisome [GO:0030089]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1qgza1_d1gaqc1__1		Viridiplantae	Cyanobacteria	Streptophyta	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	phycobilisome [GO:0030089]	chloroplast thylakoid membrane protein complex [GO:0098807]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d1qh0a2_d3qfsa2__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	phycobilisome [GO:0030089]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1qh1b__d5adwa___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	metal ion binding [GO:0046872]; iron ion transport [GO:0006826]	nitrogen fixation [GO:0009399]	iron ion transport [GO:0006826]	molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	metal ion binding [GO:0046872]
d1qh1d__d4oxrb___1			Proteobacteria		molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	
d1qh1d__d5cx1e___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1qh3a__d2qeda1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; hydroxyacylglutathione hydrolase activity [GO:0004416]; metal ion binding [GO:0046872]; glutathione biosynthetic process [GO:0006750]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; pyruvate metabolic process [GO:0006090]	hydroxyacylglutathione hydrolase activity [GO:0004416]; metal ion binding [GO:0046872]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	glutathione biosynthetic process [GO:0006750]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; pyruvate metabolic process [GO:0006090]	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]		hydroxyacylglutathione hydrolase activity [GO:0004416]; metal ion binding [GO:0046872]	hydroxyacylglutathione hydrolase activity [GO:0004416]; metal ion binding [GO:0046872]
d1qh3a__d3idzd___1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; hydroxyacylglutathione hydrolase activity [GO:0004416]; metal ion binding [GO:0046872]; glutathione biosynthetic process [GO:0006750]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; pyruvate metabolic process [GO:0006090]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	glutathione biosynthetic process [GO:0006750]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; pyruvate metabolic process [GO:0006090]	rRNA processing [GO:0006364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]	cytoplasm [GO:0005737]	hydroxyacylglutathione hydrolase activity [GO:0004416]; metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d1qh4a1_d3drea1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]	cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]
d1qh4a2_d3zxvc2__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d1qh4b1_d1g0wa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]	ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]	cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d1qh4b2_d1n16a4__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]		ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]		cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	
d1qh4c1_d3l2fi1__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]		ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]		cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	
d1qh4d1_d1qk1g1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]	creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d1qh4d1_d3l2ga1__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]		ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]		cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	
d1qh5b__d2ohii1__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; hydroxyacylglutathione hydrolase activity [GO:0004416]; metal ion binding [GO:0046872]; glutathione biosynthetic process [GO:0006750]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; pyruvate metabolic process [GO:0006090]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	glutathione biosynthetic process [GO:0006750]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; pyruvate metabolic process [GO:0006090]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]		hydroxyacylglutathione hydrolase activity [GO:0004416]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1qh6a__d1bkzb___1		Metazoa	Firmicutes	Chordata	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	xylan catabolic process [GO:0045493]	apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]
d1qhaa2_d4k42b2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d1qhaa4_d1hkca3__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1qhab2_d5aqla2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d1qhab3_d3o6wa2__1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cell [GO:0005623]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]
d1qhba__d1idua___1		Fungi	Rhodophyta	Ascomycota	metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	extracellular region [GO:0005576]; chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]				extracellular region [GO:0005576]	metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]
d1qhbd__d1vnsa___1		Fungi	Rhodophyta	Ascomycota	metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	extracellular region [GO:0005576]; chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]				extracellular region [GO:0005576]	metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]
d1qhfb__d1yfka___1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	phosphoglycerate mutase activity [GO:0004619]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]
d1qhoa4_d4go9a1__1			Firmicutes	Proteobacteria	glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d1qhpa1_d5jhma2__1			Firmicutes		glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1qhpa3_d4jcla2__1			Firmicutes	Firmicutes	glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1qhpa4_d4hp5a1__1			Firmicutes	Proteobacteria	glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d1qhqa__d4n2fa1__1		Metazoa	Chloroflexi	Chordata	plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; oxidation-reduction process [GO:0055114]; photosynthetic electron transport chain [GO:0009767]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; chromatin-mediated maintenance of transcription [GO:0048096]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]	oxidation-reduction process [GO:0055114]; photosynthetic electron transport chain [GO:0009767]	cellular response to leukemia inhibitory factor [GO:1990830]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin organization [GO:0006325]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]	plasma membrane [GO:0005886]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]
d1qhsa__d4nyiq1__1		Metazoa	Actinobacteria	Chordata	ATP binding [GO:0005524]; kinase activity [GO:0016301]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	response to antibiotic [GO:0046677]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; kinase activity [GO:0016301]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1qhza__d1v3lb4__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1qi1a__d1euha___1			Firmicutes	Firmicutes	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]					glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]
d1qi1a__d4o6rb1__1			Firmicutes	Proteobacteria	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]					glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1qi1d__d4zz7k___1			Firmicutes	Proteobacteria	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	methylmalonate-semialdehyde dehydrogenase (acylating) activity [GO:0004491]; nucleotide binding [GO:0000166]					glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	methylmalonate-semialdehyde dehydrogenase (acylating) activity [GO:0004491]; nucleotide binding [GO:0000166]
d1qi2a__d1obaa2__1			Firmicutes		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cellulose catabolic process [GO:0030245]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	lysozyme activity [GO:0003796]
d1qi4a2_d1tz7a1__1			Proteobacteria	Aquificae	extracellular region [GO:0005576]; glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; starch catabolic process [GO:0005983]	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	starch catabolic process [GO:0005983]		extracellular region [GO:0005576]	cytoplasm [GO:0005737]	glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]
d1qi4a2_d3t2qd3__1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; starch catabolic process [GO:0005983]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	starch catabolic process [GO:0005983]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1qi5a2_d3pzvd___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; starch catabolic process [GO:0005983]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	starch catabolic process [GO:0005983]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d1qi6c__d3sz9c___1		Metazoa	Firmicutes	Chordata	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d1qi6d__d2onnb___1		Metazoa	Firmicutes	Chordata	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d1qi6d__d4zxud___1			Firmicutes	Firmicutes	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; glycine betaine biosynthetic process from choline [GO:0019285]		glycine betaine biosynthetic process from choline [GO:0019285]			glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1qi8a__d2vyza___1	Metazoa	Metazoa	Chordata	Nemertea (ribbon worms)	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1qi8c__d3edaa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1qi9a__d1eoic___1				Proteobacteria	metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]				outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	acid phosphatase activity [GO:0003993]
d1qiaa__d4mwpe___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1qiab__d1ge5a___1	Metazoa	Fungi	Chordata	Basidiomycota	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1qiba__d3sckb___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1qicb__d4h57a___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1qicc__d1mnca___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1qiga__d3qmmb___1	Metazoa		Chordata	Firmicutes	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	lipid catabolic process [GO:0016042]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	extracellular region [GO:0005576]	acetylcholinesterase activity [GO:0003990]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d1qiia__d5tnfd___1	Metazoa		Chordata	Proteobacteria	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	hydrolase activity [GO:0016787]	acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]		acetylcholinesterase activity [GO:0003990]	hydrolase activity [GO:0016787]
d1qija__d4fmpb___1	Metazoa		Chordata	Firmicutes	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]		acetylcholinesterase activity [GO:0003990]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d1qika__d1a8sa___1	Metazoa		Chordata	Proteobacteria	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	chloride peroxidase activity [GO:0016691]	acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]		acetylcholinesterase activity [GO:0003990]	chloride peroxidase activity [GO:0016691]
d1qila1_d1bovb___1			Firmicutes		extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]		toxin activity [GO:0090729]	
d1qila2_d3uryb2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1qilb2_d4o1na2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; peptidase activity [GO:0008233]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	peptidase activity [GO:0008233]
d1qilc1_d1jqyf___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1qilc2_d2aq1d2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]	extracellular region [GO:0005576]	T cell receptor complex [GO:0042101]	toxin activity [GO:0090729]	
d1qipa__d2a4xa2__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; pyruvate metabolic process [GO:0006090]; regulation of transcription by RNA polymerase II [GO:0006357]		carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; pyruvate metabolic process [GO:0006090]; regulation of transcription by RNA polymerase II [GO:0006357]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]	
d1qiqa__d5pl3a___1	Fungi	Metazoa	Ascomycota	Chordata	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]; penicillin biosynthetic process [GO:0042318]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	penicillin biosynthetic process [GO:0042318]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]		blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d1qiub1_d2bsdc1__1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]		
d1qiub1_d3cncf___1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	viral capsid [GO:0019028]		
d1qiuc1_d4hemb1__1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]		
d1qiva__d1d1oa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]; calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]; calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]
d1qixb__d1v2st___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1qj2a3_d1c4aa2__1				Firmicutes		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]						4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]
d1qj2a3_d1qogb___1				Cyanobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1qj2c3_d4mlab1__1		Viridiplantae		Streptophyta		cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]		cytokinin metabolic process [GO:0009690]				cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]
d1qj2c4_d3bdjb4__1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1qj2g3_d1l5pa___1						hydrogenosome [GO:0042566]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]				hydrogenosome [GO:0042566]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1qj2h3_d3etrn1__1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1qj4a__d3gzja___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	polyneuridine-aldehyde esterase activity [GO:0050529]; alkaloid metabolic process [GO:0009820]		alkaloid metabolic process [GO:0009820]			aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	polyneuridine-aldehyde esterase activity [GO:0050529]
d1qj7.1_d1o3ha___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1qjda3_d1q9ia3__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]	electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]	electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]
d1qjga__d2b24d___1			Proteobacteria	Actinobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	steroid metabolic process [GO:0008202]	cellular metabolic process [GO:0044237]			steroid delta-isomerase activity [GO:0004769]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]
d1qjgc__d3mkib___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	steroid metabolic process [GO:0008202]	steroid metabolic process [GO:0008202]			steroid delta-isomerase activity [GO:0004769]	steroid delta-isomerase activity [GO:0004769]
d1qjgc__d4cpka1__1			Proteobacteria	Firmicutes	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	steroid metabolic process [GO:0008202]	response to antibiotic [GO:0046677]		integral component of membrane [GO:0016021]	steroid delta-isomerase activity [GO:0004769]	penicillin binding [GO:0008658]
d1qjge__d3mg1b2__1			Proteobacteria	Cyanobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	phycobilisome [GO:0030089]; chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]; light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	steroid metabolic process [GO:0008202]	light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	steroid delta-isomerase activity [GO:0004769]	chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]
d1qjgf__d2xr8l___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	steroid metabolic process [GO:0008202]	aromatic compound catabolic process [GO:0019439]			steroid delta-isomerase activity [GO:0004769]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1qjha__d2uuaf1__1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1qjsa2_d2jxya1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; heme binding [GO:0020037]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular iron ion homeostasis [GO:0006879]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cell [GO:0005623]; extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	heme binding [GO:0020037]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1qju3__d1v9u1___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1qjwb__d1hgyb___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]
d1qjx3__d1ruh3___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1qjy1__d1pgw11__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	transport of virus in host, cell to cell [GO:0046740]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1qjzc__d1bmv21__1					T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]		transport of virus in host, cell to cell [GO:0046740]	T=3 icosahedral viral capsid [GO:0039617]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1qk1a1_d3l2gn1__1	Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]	
d1qk1a2_d3l2gp2__1	Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]	
d1qk1g2_d1u6ra2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]	creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	extracellular space [GO:0005615]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d1qk1g2_d4lnob2__1	Metazoa		Chordata	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d1qk2a__d1qjwa___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]
d1qk3a__d5t3oa2__1			Apicomplexa	Deinococcus-Thermus	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; xanthine phosphoribosyltransferase activity [GO:0000310]; GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; xanthine phosphoribosyltransferase activity [GO:0000310]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]
d1qkba__d1hsea___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	protein transport [GO:0015031]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	peptide transmembrane transporter activity [GO:1904680]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d1qkzh1_d5i18l2__1			Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]		IgG binding [GO:0019864]	
d1ql3b__d1h1oa2__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1ql4b__d1fi7a___1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]		apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1qlaa5_d1l0va3__1				Proteobacteria		cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]		2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1qlab3_d5g5ha1__1				Proteobacteria		periplasmic space [GO:0042597]; carboxylate reductase activity [GO:0047770]; molybdenum ion binding [GO:0030151]; oxidoreductase activity, acting on the aldehyde or oxo group of donors [GO:0016903]; cellular response to DNA damage stimulus [GO:0006974]		cellular response to DNA damage stimulus [GO:0006974]		periplasmic space [GO:0042597]		carboxylate reductase activity [GO:0047770]; molybdenum ion binding [GO:0030151]; oxidoreductase activity, acting on the aldehyde or oxo group of donors [GO:0016903]
d1qlae3_d2wlba___1		Fungi		Ascomycota		integral component of mitochondrial inner membrane [GO:0031305]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on NAD(P)H [GO:0016651]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; [2Fe-2S] cluster assembly [GO:0044571]; heme a biosynthetic process [GO:0006784]; respiratory electron transport chain [GO:0022904]		[2Fe-2S] cluster assembly [GO:0044571]; heme a biosynthetic process [GO:0006784]; respiratory electron transport chain [GO:0022904]		integral component of mitochondrial inner membrane [GO:0031305]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on NAD(P)H [GO:0016651]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d1qlbd3_d2wp9e2__1			Proteobacteria	Proteobacteria	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	respirasome [GO:0070469]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d1qleb1_d1a4cb___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respiratory chain complex IV [GO:0045277]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; aerobic respiration [GO:0009060]; electron transport coupled proton transport [GO:0015990]; oxidative phosphorylation [GO:0006119]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	aerobic respiration [GO:0009060]; electron transport coupled proton transport [GO:0015990]; oxidative phosphorylation [GO:0006119]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respiratory chain complex IV [GO:0045277]	periplasmic space [GO:0042597]	cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1qleh__d5d7ke2__1			Proteobacteria		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respiratory chain complex IV [GO:0045277]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; aerobic respiration [GO:0009060]; electron transport coupled proton transport [GO:0015990]; oxidative phosphorylation [GO:0006119]		aerobic respiration [GO:0009060]; electron transport coupled proton transport [GO:0015990]; oxidative phosphorylation [GO:0006119]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respiratory chain complex IV [GO:0045277]		cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d1qlel__d1opgl2__1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respiratory chain complex IV [GO:0045277]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; aerobic respiration [GO:0009060]; electron transport coupled proton transport [GO:0015990]; oxidative phosphorylation [GO:0006119]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	aerobic respiration [GO:0009060]; electron transport coupled proton transport [GO:0015990]; oxidative phosphorylation [GO:0006119]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respiratory chain complex IV [GO:0045277]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1qlfa1_d3qnxb1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1qlha2_d1pedd2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]
d1qlkb__d2mrdb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d1qlra1_d2vq1e1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1qlra1_d4qf1l1__1	Metazoa		Chordata									
d1qlra2_d5e99l2__1	Metazoa		Chordata									
d1qlrc1_d2igfh2__1	Metazoa	Metazoa	Chordata	Annelida		iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]						iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]
d1qlrd1_d1mcfb2__1	Metazoa	Metazoa	Chordata	Chordata								
d1qlta1_d2bvha1__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]		FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]
d1qltb1_d4ml8c2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]	methanol metabolic process [GO:0015945]	cytokinin metabolic process [GO:0009690]	peroxisome [GO:0005777]		FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]
d1qlva2_d1cmla1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	biosynthetic process [GO:0009058]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]			transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	naringenin-chalcone synthase activity [GO:0016210]
d1qlva2_d2aq7b1__1	Viridiplantae		Streptophyta	Proteobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1qlvb2_d3gwea1__1	Viridiplantae		Streptophyta	Proteobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]			transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1qm0a__d3o79a___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; protein homooligomerization [GO:0051260]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	protein homooligomerization [GO:0051260]	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	metal ion binding [GO:0046872]
d1qm1a__d3haka___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d1qm4a1_d5t8sa1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]
d1qm4a2_d5t8ta2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]
d1qm4b2_d2hj2b2__1	Metazoa		Chordata		cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]		methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]		cytosol [GO:0005829]; nuclear matrix [GO:0016363]		ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	
d1qm4b3_d4le5a3__1	Metazoa		Chordata		cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]		methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]		cytosol [GO:0005829]; nuclear matrix [GO:0016363]		ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]	
d1qm5a__d5u6sa___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; maltodextrin phosphorylase activity [GO:0031220]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]; alpha-glucan catabolic process [GO:0030980]; glycogen catabolic process [GO:0005980]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; benzoic acid glucosyltransferase activity [GO:0052641]; nicotinate-O-glucosyltransferase activity [GO:0090704]; quercetin 3-O-glucosyltransferase activity [GO:0080043]; quercetin 7-O-glucosyltransferase activity [GO:0080044]; salicylic acid glucosyltransferase (ester-forming) activity [GO:0052639]; salicylic acid glucosyltransferase (glucoside-forming) activity [GO:0052640]; UDP-glucose:4-aminobenzoate acylglucosyltransferase activity [GO:0080002]; UDP-glucosyltransferase activity [GO:0035251]; UDP-glycosyltransferase activity [GO:0008194]; benzoate metabolic process [GO:0018874]; para-aminobenzoic acid metabolic process [GO:0046482]; positive regulation of seed germination [GO:0010030]; salicylic acid metabolic process [GO:0009696]	alpha-glucan catabolic process [GO:0030980]; glycogen catabolic process [GO:0005980]	benzoate metabolic process [GO:0018874]; para-aminobenzoic acid metabolic process [GO:0046482]; positive regulation of seed germination [GO:0010030]; salicylic acid metabolic process [GO:0009696]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]	glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; maltodextrin phosphorylase activity [GO:0031220]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]	benzoic acid glucosyltransferase activity [GO:0052641]; nicotinate-O-glucosyltransferase activity [GO:0090704]; quercetin 3-O-glucosyltransferase activity [GO:0080043]; quercetin 7-O-glucosyltransferase activity [GO:0080044]; salicylic acid glucosyltransferase (ester-forming) activity [GO:0052639]; salicylic acid glucosyltransferase (glucoside-forming) activity [GO:0052640]; UDP-glucose:4-aminobenzoate acylglucosyltransferase activity [GO:0080002]; UDP-glucosyltransferase activity [GO:0035251]; UDP-glycosyltransferase activity [GO:0008194]
d1qm5b__d2ii6a1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; maltodextrin phosphorylase activity [GO:0031220]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]; alpha-glucan catabolic process [GO:0030980]; glycogen catabolic process [GO:0005980]	transferase activity, transferring glycosyl groups [GO:0016757]	alpha-glucan catabolic process [GO:0030980]; glycogen catabolic process [GO:0005980]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; maltodextrin phosphorylase activity [GO:0031220]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]	transferase activity, transferring glycosyl groups [GO:0016757]
d1qm6b1_d1ak0a___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; DNA catabolic process [GO:0006308]	hemolysis in other organism [GO:0044179]	DNA catabolic process [GO:0006308]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1qm9a2_d3h2vf1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; membrane raft [GO:0045121]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; terminal web [GO:1990357]; zonula adherens [GO:0005915]; actin binding [GO:0003779]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]; adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; muscle contraction [GO:0006936]; negative regulation of cell migration [GO:0030336]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; protein localization to cell surface [GO:0034394]	fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; muscle contraction [GO:0006936]; negative regulation of cell migration [GO:0030336]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; protein localization to cell surface [GO:0034394]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; membrane raft [GO:0045121]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; terminal web [GO:1990357]; zonula adherens [GO:0005915]	poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]	actin binding [GO:0003779]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]
d1qm9a2_d5uzma___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	protein-containing complex [GO:0032991]; mRNA binding [GO:0003729]; chromosome organization [GO:0051276]; intracellular mRNA localization involved in pattern specification process [GO:0060810]; maternal specification of dorsal/ventral axis, oocyte, germ-line encoded [GO:0007311]; pole plasm oskar mRNA localization [GO:0045451]; regulation of translation [GO:0006417]; wound healing [GO:0042060]	fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	chromosome organization [GO:0051276]; intracellular mRNA localization involved in pattern specification process [GO:0060810]; maternal specification of dorsal/ventral axis, oocyte, germ-line encoded [GO:0007311]; pole plasm oskar mRNA localization [GO:0045451]; regulation of translation [GO:0006417]; wound healing [GO:0042060]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	protein-containing complex [GO:0032991]	poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]	mRNA binding [GO:0003729]
d1qmab__d1u5oa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]
d1qmab__d1uuwb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]		identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	dioxygenase activity [GO:0051213]
d1qmad__d3nhxa___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]		identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	steroid delta-isomerase activity [GO:0004769]
d1qmda1_d5fbda___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleic acid binding [GO:0003676]; DNA catabolic process [GO:0006308]	hemolysis in other organism [GO:0044179]	DNA catabolic process [GO:0006308]	extracellular region [GO:0005576]		hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleic acid binding [GO:0003676]
d1qmdb1_d1olpd1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	phospholipase C activity [GO:0004629]; zinc ion binding [GO:0008270]	hemolysis in other organism [GO:0044179]		extracellular region [GO:0005576]		hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	phospholipase C activity [GO:0004629]; zinc ion binding [GO:0008270]
d1qmga1_d2gera2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	chloroplast [GO:0009507]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1qmga2_d1m76a2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d1qmgb2_d4bhtf2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	glutamate biosynthetic process [GO:0006537]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]
d1qmo.2_d3pvom___1	Viridiplantae	Metazoa	Streptophyta	Chordata	protein storage vacuole lumen [GO:0034495]; carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	protein storage vacuole lumen [GO:0034495]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1qmo.3_d1w0pa1__1	Viridiplantae		Streptophyta	Proteobacteria	protein storage vacuole lumen [GO:0034495]; carbohydrate binding [GO:0030246]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]; ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]		ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]	protein storage vacuole lumen [GO:0034495]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]	carbohydrate binding [GO:0030246]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]
d1qmra__d4n3ep___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	cytoplasm [GO:0005737]		abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d1qmua2_d3nh8a___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; metallocarboxypeptidase activity [GO:0004181]; serine-type carboxypeptidase activity [GO:0004185]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; aminoacylase activity [GO:0004046]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	proteolysis [GO:0006508]		integral component of membrane [GO:0016021]	apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	metallocarboxypeptidase activity [GO:0004181]; serine-type carboxypeptidase activity [GO:0004185]; zinc ion binding [GO:0008270]	aminoacylase activity [GO:0004046]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1qmya__d3of8a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; histone binding [GO:0042393]; proteoglycan binding [GO:0043394]; serpin family protein binding [GO:0097655]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; macrophage apoptotic process [GO:0071888]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; macrophage apoptotic process [GO:0071888]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; histone binding [GO:0042393]; proteoglycan binding [GO:0043394]; serpin family protein binding [GO:0097655]
d1qmyb__d1qolh___1					host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1qmzb2_d4bcod2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1qn1a__d2cyma___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	anaerobic respiration [GO:0009061]	anaerobic respiration [GO:0009061]		periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1qn2b__d3l72q1__1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]				integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1qn4a1_d3d4vc2__1	Viridiplantae		Streptophyta	Proteobacteria	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1qn5b1_d3cwsa2__1	Viridiplantae		Streptophyta	Proteobacteria	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1qn5b2_d3cvsd2__1	Viridiplantae		Streptophyta	Proteobacteria	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1qn6a2_d3cw7d2__1	Viridiplantae		Streptophyta	Proteobacteria	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1qn7b1_d3ocib1__1	Viridiplantae	Fungi	Streptophyta	Microsporidia	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]; DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]		DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]
d1qn8a2_d1qn5b1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1qn8b2_d3cwac2__1	Viridiplantae		Streptophyta	Proteobacteria	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1qn9b1_d1c9bj1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1qnab1_d1ngme2__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]
d1qnbb1_d1tbpb2__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]
d1qnca2_d3oc3d2__1	Viridiplantae	Fungi	Streptophyta	Microsporidia	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]		nucleus [GO:0005634]; transcription factor complex [GO:0005667]		DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]
d1qncb1_d1mpgb2__1	Viridiplantae		Streptophyta	Proteobacteria	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1qnda__d2ksha___1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; cholesterol binding [GO:0015485]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]; oleic acid binding [GO:0070538]; phosphatidylinositol transfer activity [GO:0008526]; propanoyl-CoA C-acyltransferase activity [GO:0033814]; propionyl-CoA C2-trimethyltridecanoyltransferase activity [GO:0050632]; signaling receptor binding [GO:0005102]; alpha-linolenic acid metabolic process [GO:0036109]; bile acid biosynthetic process [GO:0006699]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid hydroperoxide transport [GO:1901373]; phospholipid transport [GO:0015914]; positive regulation of intracellular cholesterol transport [GO:0032385]; positive regulation of steroid metabolic process [GO:0045940]; progesterone biosynthetic process [GO:0006701]; protein localization to plasma membrane [GO:0072659]; protein targeting to peroxisome [GO:0006625]; steroid biosynthetic process [GO:0006694]		alpha-linolenic acid metabolic process [GO:0036109]; bile acid biosynthetic process [GO:0006699]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid hydroperoxide transport [GO:1901373]; phospholipid transport [GO:0015914]; positive regulation of intracellular cholesterol transport [GO:0032385]; positive regulation of steroid metabolic process [GO:0045940]; progesterone biosynthetic process [GO:0006701]; protein localization to plasma membrane [GO:0072659]; protein targeting to peroxisome [GO:0006625]; steroid biosynthetic process [GO:0006694]		cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]		cholesterol binding [GO:0015485]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]; oleic acid binding [GO:0070538]; phosphatidylinositol transfer activity [GO:0008526]; propanoyl-CoA C-acyltransferase activity [GO:0033814]; propionyl-CoA C2-trimethyltridecanoyltransferase activity [GO:0050632]; signaling receptor binding [GO:0005102]	
d1qnfa1_d4u8hc2__1		Metazoa	Cyanobacteria	Chordata	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; histone deacetylase binding [GO:0042826]; histone methyltransferase binding [GO:1990226]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; pre-mRNA binding [GO:0036002]; RNA polymerase binding [GO:0070063]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription coactivator activity [GO:0003713]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; circadian regulation of gene expression [GO:0032922]; circadian regulation of translation [GO:0097167]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; fatty acid metabolic process [GO:0006631]; gluconeogenesis [GO:0006094]; glycogen biosynthetic process [GO:0005978]; histone H3 deacetylation [GO:0070932]; lactate biosynthetic process [GO:0019249]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription, termination [GO:0060567]; negative regulation of fat cell proliferation [GO:0070345]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051946]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of vasoconstriction [GO:0019229]; response to ischemia [GO:0002931]; response to light stimulus [GO:0009416]; white fat cell differentiation [GO:0050872]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	circadian regulation of gene expression [GO:0032922]; circadian regulation of translation [GO:0097167]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; fatty acid metabolic process [GO:0006631]; gluconeogenesis [GO:0006094]; glycogen biosynthetic process [GO:0005978]; histone H3 deacetylation [GO:0070932]; lactate biosynthetic process [GO:0019249]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription, termination [GO:0060567]; negative regulation of fat cell proliferation [GO:0070345]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051946]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of vasoconstriction [GO:0019229]; response to ischemia [GO:0002931]; response to light stimulus [GO:0009416]; white fat cell differentiation [GO:0050872]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	histone deacetylase binding [GO:0042826]; histone methyltransferase binding [GO:1990226]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; pre-mRNA binding [GO:0036002]; RNA polymerase binding [GO:0070063]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription coactivator activity [GO:0003713]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1qnhb__d2mvza___1			Apicomplexa	Firmicutes	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	protein folding [GO:0006457]	protein folding [GO:0006457]			peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1qnia1_d2bp8a1__1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	membrane [GO:0016020]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1qnic1_d3jtba___1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	membrane [GO:0016020]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1qnid1_d1fwxc1__1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]		denitrification pathway [GO:0019333]	membrane [GO:0016020]	membrane [GO:0016020]; periplasmic space [GO:0042597]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d1qnja__d1o32a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1qnma1_d2ce4b1__1	Metazoa		Chordata	Deinococcus-Thermus	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1qnma2_d1en5b2__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1qnmb1_d4l2cc1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1qnna2_d5tira2__1		Fungi	Bacteroidetes	Ascomycota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1qnnb2_d4guna2__1		Fungi	Bacteroidetes	Ascomycota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1qnnc1_d4br6c1__1		Fungi	Bacteroidetes	Ascomycota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1qnoa__d1ogsb2__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	cellulose binding [GO:0030248]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1qnra__d4k68b___1	Fungi		Ascomycota		extracellular region [GO:0005576]; cellulose binding [GO:0030248]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cellulose binding [GO:0030248]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]	
d1qnsa__d1jz8d5__1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	cellulose binding [GO:0030248]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1qnsa__d3ayra1__1	Fungi	Fungi	Ascomycota	Chytridiomycota	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cellulose binding [GO:0030248]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1qnta1_d1t38a1__1	Metazoa	Metazoa	Chordata	Chordata	membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; metal ion binding [GO:0046872]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; methyltransferase activity [GO:0008168]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of double-strand break repair [GO:2000781]	membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; metal ion binding [GO:0046872]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; methyltransferase activity [GO:0008168]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of double-strand break repair [GO:2000781]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of double-strand break repair [GO:2000781]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of double-strand break repair [GO:2000781]	membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; metal ion binding [GO:0046872]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; methyltransferase activity [GO:0008168]	DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; metal ion binding [GO:0046872]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; methyltransferase activity [GO:0008168]
d1qnwc__d1jycb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1qnwd__d1macb___1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	licheninase activity [GO:0042972]
d1qnzl1_d3mrlb1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1qo0a__d1tlfa___1			Proteobacteria	Proteobacteria	amide binding [GO:0033218]; kinase activity [GO:0016301]; amino acid transport [GO:0006865]; negative regulation of hydrolase activity [GO:0051346]; regulation of cellular amide catabolic process [GO:0034251]	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	amino acid transport [GO:0006865]; negative regulation of hydrolase activity [GO:0051346]; regulation of cellular amide catabolic process [GO:0034251]	negative regulation of transcription, DNA-templated [GO:0045892]		cytosol [GO:0005829]	amide binding [GO:0033218]; kinase activity [GO:0016301]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]
d1qo3d__d1rdn1___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]
d1qo3d__d3altc___1	Metazoa	Metazoa	Chordata	Echinodermata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	metal ion binding [GO:0046872]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]
d1qo5g__d2nxhc___1	Metazoa		Chordata	Aquificae	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose binding [GO:0070061]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]; canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]	cytoplasm [GO:0005737]	ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose binding [GO:0070061]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]
d1qo5l__d2yr1a___1	Metazoa		Chordata	Firmicutes	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose binding [GO:0070061]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]; canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]		ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose binding [GO:0070061]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]	3-dehydroquinate dehydratase activity [GO:0003855]
d1qo5m__d1vpxd1__1	Metazoa		Chordata	Thermotogae	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose binding [GO:0070061]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]; canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]	cytoplasm [GO:0005737]	ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose binding [GO:0070061]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d1qo5m__d4wozg___1	Metazoa		Chordata	Firmicutes	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose binding [GO:0070061]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]; canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	cytoplasm [GO:0005737]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]	cytoplasm [GO:0005737]	ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose binding [GO:0070061]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]	N-acetylneuraminate lyase activity [GO:0008747]
d1qo5n__d4s1fn1__1	Metazoa		Chordata	Proteobacteria	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose binding [GO:0070061]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]; canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	fructose metabolic process [GO:0006000]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]	cytoplasm [GO:0005737]	ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose binding [GO:0070061]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]	fructose 6-phosphate aldolase activity [GO:0097023]
d1qoaa__d3vr8b1__1		Metazoa	Cyanobacteria	Nematoda (roundworms)	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d1qoab__d2w3se1__1			Cyanobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1qoba__d3bdja1__1		Metazoa	Cyanobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1qobb__d1qlbe2__1			Cyanobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]		respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d1qoda__d3lxfc___1				Proteobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1qoea__d3nvwj1__1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1qofa__d1jroe2__1			Cyanobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1qofb__d3w5ub___1		Viridiplantae	Cyanobacteria	Streptophyta	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]		electron transport chain [GO:0022900]; photosynthesis [GO:0015979]		chloroplast thylakoid membrane protein complex [GO:0098807]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d1qohb__d1eeie___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1qohc__d5eldb___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1qohh__d1fnva1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]		toxin activity [GO:0090729]
d1qohh__d1s5ch___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]		galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]
d1qohl__d1lt5f___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		toxin activity [GO:0090729]
d1qohl__d1v1ob1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1qoho__d1ltie___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		toxin activity [GO:0090729]
d1qoia__d2rmba___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U4/U6 snRNP [GO:0071001]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; ribonucleoprotein complex binding [GO:0043021]; unfolded protein binding [GO:0051082]; angiogenesis [GO:0001525]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; protein-containing complex assembly [GO:0065003]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	angiogenesis [GO:0001525]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein-containing complex assembly [GO:0065003]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U4/U6 snRNP [GO:0071001]; U4/U6 x U5 tri-snRNP complex [GO:0046540]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; ribonucleoprotein complex binding [GO:0043021]; unfolded protein binding [GO:0051082]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1qoka1_d1olza1__1	Metazoa	Metazoa	Chordata	Chordata		extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; chemorepellent activity [GO:0045499]; identical protein binding [GO:0042802]; semaphorin receptor binding [GO:0030215]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; cell adhesion [GO:0007155]; immune response [GO:0006955]; leukocyte aggregation [GO:0070486]; negative chemotaxis [GO:0050919]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; ossification involved in bone maturation [GO:0043931]; positive regulation of cell migration [GO:0030335]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of GTPase activity [GO:0043547]; positive regulation of inhibitory synapse assembly [GO:1905704]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell projection organization [GO:0031344]; regulation of cell shape [GO:0008360]; regulation of dendrite morphogenesis [GO:0048814]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220]		cell adhesion [GO:0007155]; immune response [GO:0006955]; leukocyte aggregation [GO:0070486]; negative chemotaxis [GO:0050919]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; ossification involved in bone maturation [GO:0043931]; positive regulation of cell migration [GO:0030335]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of GTPase activity [GO:0043547]; positive regulation of inhibitory synapse assembly [GO:1905704]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell projection organization [GO:0031344]; regulation of cell shape [GO:0008360]; regulation of dendrite morphogenesis [GO:0048814]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220]		extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		chemorepellent activity [GO:0045499]; identical protein binding [GO:0042802]; semaphorin receptor binding [GO:0030215]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]
d1qoka2_d4q2zb2__1	Metazoa		Chordata									
d1qoka2_d5ja9a1__1	Metazoa		Chordata	Proteobacteria								
d1qolh__d2bdla___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d1qoob__d1v6mb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1qoob__d2r1dc1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]		angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]		axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]
d1qora2_d1n8kb2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; NADPH:quinone reductase activity [GO:0003960]; zinc ion binding [GO:0008270]; cellular response to oxidative stress [GO:0034599]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cellular response to oxidative stress [GO:0034599]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	NADPH:quinone reductase activity [GO:0003960]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1qotc__d2zgla1__1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]		apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d1qotd__d1dbna___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1qoxb__d1bggc___1			Firmicutes	Firmicutes	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1qoxd__d5okbc___1			Firmicutes	Firmicutes	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	6-phospho-beta-galactosidase activity [GO:0033920]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	6-phospho-beta-galactosidase activity [GO:0033920]
d1qoxe__d5dt5a___1			Firmicutes	Firmicutes	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1qoxf__d4x0vf___1			Firmicutes	Firmicutes	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1qoxg__d2wt6a1__1			Firmicutes		beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]				beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	
d1qoxi__d2j74a___1			Firmicutes	Firmicutes	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	cellulose catabolic process [GO:0030245]	metabolic process [GO:0008152]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]
d1qoxk__d2wbga___1			Firmicutes	Thermotogae	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1qoxl__d1e71m___1		Viridiplantae	Firmicutes	Streptophyta	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]		vacuole [GO:0005773]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]
d1qoxn__d3vd9d3__1			Firmicutes	Proteobacteria	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1qoxp__d2cbvb___1			Firmicutes	Thermotogae	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1qozb__d1xzka___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; acetylxylan esterase activity [GO:0046555]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	acetylxylan esterase activity [GO:0046555]; cellulose binding [GO:0030248]	cutinase activity [GO:0050525]
d1qozb__d2iitb2__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; acetylxylan esterase activity [GO:0046555]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	acetylxylan esterase activity [GO:0046555]; cellulose binding [GO:0030248]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1qp1a__d4xmpl2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1qp1c__d1duze___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1qp1c__d1lhzb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; identical protein binding [GO:0042802]	
d1qpba3_d2c3pa2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	electron transport chain [GO:0022900]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d1qpbb3_d5hyva2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1qpfd__d3tc5a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]
d1qpka2_d1px3b5__1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; starch catabolic process [GO:0005983]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	starch catabolic process [GO:0005983]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	glucan 1,4-alpha-maltotetraohydrolase activity [GO:0033910]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1qpnb2_d3l0ga1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qpnd2_d1yira2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cytosol [GO:0005829]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]
d1qpoa1_d5hulb2__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qpob2_d3l0gd1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qpod1_d1x1ob2__1			Actinobacteria	Deinococcus-Thermus	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qpod1_d1ytka2__1			Actinobacteria	Euryarchaeota	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	metal ion binding [GO:0046872]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nucleotide binding [GO:0000166]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nucleotide binding [GO:0000166]
d1qpod2_d5huoh1__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qpqb1_d1x1oa2__1			Actinobacteria	Deinococcus-Thermus	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qpqb2_d2im5a1__1			Actinobacteria	Bacteroidetes	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]
d1qpqc2_d3l0gc1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qpqd1_d3l0gd2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qpqd2_d1x1oc1__1			Actinobacteria	Deinococcus-Thermus	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qpqf1_d2im5d2__1			Actinobacteria	Bacteroidetes	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]
d1qpra1_d2b7na2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qprb1_d5huoa2__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qprc2_d2im5c1__1			Actinobacteria	Bacteroidetes	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]
d1qprd2_d1x1oa1__1			Actinobacteria	Deinococcus-Thermus	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qprf2_d2i14c2__1			Actinobacteria	Euryarchaeota	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1qpva__d1ak6a___1	Fungi	Metazoa	Ascomycota	Chordata	actin cortical patch [GO:0030479]; actin cytoskeleton [GO:0015629]; nuclear matrix [GO:0016363]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]	cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]; actin filament severing [GO:0051014]; positive regulation of actin filament depolymerization [GO:0030836]	actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]	actin filament depolymerization [GO:0030042]; actin filament severing [GO:0051014]; positive regulation of actin filament depolymerization [GO:0030836]	actin cortical patch [GO:0030479]; actin cytoskeleton [GO:0015629]; nuclear matrix [GO:0016363]; plasma membrane [GO:0005886]	cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]	actin filament binding [GO:0051015]	actin binding [GO:0003779]
d1qpva__d2fh2c2__1	Fungi	Metazoa	Ascomycota	Chordata	actin cortical patch [GO:0030479]; actin cytoskeleton [GO:0015629]; nuclear matrix [GO:0016363]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cortical patch [GO:0030479]; actin cytoskeleton [GO:0015629]; nuclear matrix [GO:0016363]; plasma membrane [GO:0005886]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament binding [GO:0051015]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1qq2a__d2wjug1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]; heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	glutathione transferase activity [GO:0004364]
d1qq8b__d1uddd___1				Euryarchaeota		thiaminase activity [GO:0050334]; thiamine metabolic process [GO:0006772]		thiamine metabolic process [GO:0006772]				thiaminase activity [GO:0050334]
d1qq8b__d1xk0b___1		Metazoa		Chordata		caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]		angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]		caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]		enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1qqba2_d1sxgi___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]; negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]	regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]	DNA binding [GO:0003677]
d1qqda2_d1tvha2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1qqga1_d2aeha2__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; insulin receptor complex [GO:0005899]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; insulin receptor binding [GO:0005158]; insulin-like growth factor receptor binding [GO:0005159]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein kinase C binding [GO:0005080]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; cellular response to fatty acid [GO:0071398]; cellular response to insulin stimulus [GO:0032869]; glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; interleukin-7-mediated signaling pathway [GO:0038111]; MAPK cascade [GO:0000165]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of insulin secretion [GO:0046676]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase B signaling [GO:0051897]; response to insulin [GO:0032868]; response to peptide hormone [GO:0043434]; signal transduction [GO:0007165]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]; actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	cellular response to fatty acid [GO:0071398]; cellular response to insulin stimulus [GO:0032869]; glucose homeostasis [GO:0042593]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-7-mediated signaling pathway [GO:0038111]; MAPK cascade [GO:0000165]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of insulin secretion [GO:0046676]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase B signaling [GO:0051897]; response to insulin [GO:0032868]; response to peptide hormone [GO:0043434]; signal transduction [GO:0007165]	actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	caveola [GO:0005901]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; insulin receptor complex [GO:0005899]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]	insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein kinase C binding [GO:0005080]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]	ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]
d1qqja2_d5ti1b2__1	Metazoa		Chordata	Proteobacteria	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]; arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]; aromatic amino acid family metabolic process [GO:0009072]	arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	aromatic amino acid family metabolic process [GO:0009072]			fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]
d1qqjb1_d4qkuc1__1	Metazoa		Chordata	Proteobacteria	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]; arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	fumarylacetoacetase activity [GO:0004334]; aromatic amino acid family metabolic process [GO:0009072]	arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	aromatic amino acid family metabolic process [GO:0009072]			fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]	fumarylacetoacetase activity [GO:0004334]
d1qqma2_d3dawa2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d1qqna1_d2d0oa3__1	Metazoa		Chordata	Proteobacteria	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]		axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]		autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	
d1qqoa1_d1x9jh2__1	Metazoa		Chordata	Thermotogae	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]		autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]
d1qqoa2_d1bwfy1__1	Metazoa		Chordata	Proteobacteria	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytosol [GO:0005829]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d1qqp3__d1ng0b___1					host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; peptidase activity [GO:0008233]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; peptidase activity [GO:0008233]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]
d1qqrc__d1c4pb___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]; plasminogen activation [GO:0031639]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]; plasminogen activation [GO:0031639]	pathogenesis [GO:0009405]; plasminogen activation [GO:0031639]	pathogenesis [GO:0009405]; plasminogen activation [GO:0031639]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1qqva__d2l3xa___1	Metazoa	Metazoa	Chordata	Chordata	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; actin filament binding [GO:0051015]; metal ion binding [GO:0046872]; actin cytoskeleton organization [GO:0030036]; lamellipodium assembly [GO:0030032]; transcription, DNA-templated [GO:0006351]	actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	actin cytoskeleton organization [GO:0030036]; lamellipodium assembly [GO:0030032]; transcription, DNA-templated [GO:0006351]	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; metal ion binding [GO:0046872]
d1qqya__d3cdod___1	Metazoa		Chordata		lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]; cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]	lysozyme activity [GO:0003796]
d1qr1d1_d4xbgi1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1qr2b__d2q9ub2__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1qr4b1_d1tena___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; cell adhesion [GO:0007155]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; interstitial matrix [GO:0005614]; membrane [GO:0016020]; perisynaptic extracellular matrix [GO:0098966]; extracellular matrix structural constituent [GO:0005201]; syndecan binding [GO:0045545]; bud outgrowth involved in lung branching [GO:0060447]; cell adhesion [GO:0007155]; cellular protein metabolic process [GO:0044267]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin D [GO:0071305]; extracellular matrix organization [GO:0030198]; mesenchymal-epithelial cell signaling involved in prostate gland development [GO:0060739]; negative regulation of cell adhesion [GO:0007162]; neuromuscular junction development [GO:0007528]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; post-translational protein modification [GO:0043687]; prostate gland epithelium morphogenesis [GO:0060740]; response to ethanol [GO:0045471]; response to fibroblast growth factor [GO:0071774]; response to mechanical stimulus [GO:0009612]; response to wounding [GO:0009611]; wound healing [GO:0042060]	cell adhesion [GO:0007155]	bud outgrowth involved in lung branching [GO:0060447]; cell adhesion [GO:0007155]; cellular protein metabolic process [GO:0044267]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin D [GO:0071305]; extracellular matrix organization [GO:0030198]; mesenchymal-epithelial cell signaling involved in prostate gland development [GO:0060739]; negative regulation of cell adhesion [GO:0007162]; neuromuscular junction development [GO:0007528]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; post-translational protein modification [GO:0043687]; prostate gland epithelium morphogenesis [GO:0060740]; response to ethanol [GO:0045471]; response to fibroblast growth factor [GO:0071774]; response to mechanical stimulus [GO:0009612]; response to wounding [GO:0009611]; wound healing [GO:0042060]	extracellular region [GO:0005576]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; interstitial matrix [GO:0005614]; membrane [GO:0016020]; perisynaptic extracellular matrix [GO:0098966]		extracellular matrix structural constituent [GO:0005201]; syndecan binding [GO:0045545]
d1qrga__d1kk4d___1			Euryarchaeota	Firmicutes	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]			bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	transferase activity, transferring acyl groups [GO:0016746]
d1qrha__d1cl8a___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]
d1qrka3_d4pygb4__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1qrkb2_d1sgxb7__1	Metazoa		Chordata		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]		blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]		metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	
d1qrkb4_d4klba___1	Metazoa		Chordata		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cysteine-type endopeptidase activity [GO:0004197]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]		metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	cysteine-type endopeptidase activity [GO:0004197]
d1qrla__d3vnpa1__1			Euryarchaeota	Firmicutes	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]					bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1qrla__d4e8lb___1			Euryarchaeota		bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]						bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	
d1qrma__d4aa7a2__1			Euryarchaeota	Proteobacteria	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytosol [GO:0005829]	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d1qrna2_d1rjzd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1qrnb2_d2aj3c1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1qrnd1_d4gw4b2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1qrnd2_d2nz9c1__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	negative regulation of neurotransmitter secretion [GO:0046929]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1qrne2_d1mlcd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1qrqb__d2wzmb___1	Metazoa		Chordata	Actinobacteria	axon [GO:0030424]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; juxtaparanode region of axon [GO:0044224]; neuron projection [GO:0043005]; pinceau fiber [GO:1990031]; potassium channel complex [GO:0034705]; synapse [GO:0045202]; aldo-keto reductase (NADP) activity [GO:0004033]; ion channel binding [GO:0044325]; potassium channel regulator activity [GO:0015459]; voltage-gated potassium channel activity [GO:0005249]; myoblast differentiation [GO:0045445]; NADPH oxidation [GO:0070995]; oxidation-reduction process [GO:0055114]; protein heterooligomerization [GO:0051291]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008]	oxidoreductase activity [GO:0016491]	myoblast differentiation [GO:0045445]; NADPH oxidation [GO:0070995]; oxidation-reduction process [GO:0055114]; protein heterooligomerization [GO:0051291]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008]		axon [GO:0030424]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; juxtaparanode region of axon [GO:0044224]; neuron projection [GO:0043005]; pinceau fiber [GO:1990031]; potassium channel complex [GO:0034705]; synapse [GO:0045202]		aldo-keto reductase (NADP) activity [GO:0004033]; ion channel binding [GO:0044325]; potassium channel regulator activity [GO:0015459]; voltage-gated potassium channel activity [GO:0005249]	oxidoreductase activity [GO:0016491]
d1qrqb__d3ghta___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; juxtaparanode region of axon [GO:0044224]; neuron projection [GO:0043005]; pinceau fiber [GO:1990031]; potassium channel complex [GO:0034705]; synapse [GO:0045202]; aldo-keto reductase (NADP) activity [GO:0004033]; ion channel binding [GO:0044325]; potassium channel regulator activity [GO:0015459]; voltage-gated potassium channel activity [GO:0005249]; myoblast differentiation [GO:0045445]; NADPH oxidation [GO:0070995]; oxidation-reduction process [GO:0055114]; protein heterooligomerization [GO:0051291]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	myoblast differentiation [GO:0045445]; NADPH oxidation [GO:0070995]; oxidation-reduction process [GO:0055114]; protein heterooligomerization [GO:0051291]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	axon [GO:0030424]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; juxtaparanode region of axon [GO:0044224]; neuron projection [GO:0043005]; pinceau fiber [GO:1990031]; potassium channel complex [GO:0034705]; synapse [GO:0045202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	aldo-keto reductase (NADP) activity [GO:0004033]; ion channel binding [GO:0044325]; potassium channel regulator activity [GO:0015459]; voltage-gated potassium channel activity [GO:0005249]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d1qrqd__d2heja___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; juxtaparanode region of axon [GO:0044224]; neuron projection [GO:0043005]; pinceau fiber [GO:1990031]; potassium channel complex [GO:0034705]; synapse [GO:0045202]; aldo-keto reductase (NADP) activity [GO:0004033]; ion channel binding [GO:0044325]; potassium channel regulator activity [GO:0015459]; voltage-gated potassium channel activity [GO:0005249]; myoblast differentiation [GO:0045445]; NADPH oxidation [GO:0070995]; oxidation-reduction process [GO:0055114]; protein heterooligomerization [GO:0051291]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008]	cytosol [GO:0005829]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	myoblast differentiation [GO:0045445]; NADPH oxidation [GO:0070995]; oxidation-reduction process [GO:0055114]; protein heterooligomerization [GO:0051291]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008]	oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	axon [GO:0030424]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; juxtaparanode region of axon [GO:0044224]; neuron projection [GO:0043005]; pinceau fiber [GO:1990031]; potassium channel complex [GO:0034705]; synapse [GO:0045202]	cytosol [GO:0005829]	aldo-keto reductase (NADP) activity [GO:0004033]; ion channel binding [GO:0044325]; potassium channel regulator activity [GO:0015459]; voltage-gated potassium channel activity [GO:0005249]	17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]
d1qrsa2_d4hjrb___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	tyrosyl-tRNA aminoacylation [GO:0006437]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]
d1qrta2_d2q1ia1__1			Proteobacteria		cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]		glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]		cytosol [GO:0005829]		ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]	
d1qrva__d1hmfa___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]; chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 5S rRNA binding [GO:0008097]; bent DNA binding [GO:0003681]; bubble DNA binding [GO:0000405]; crossed form four-way junction DNA binding [GO:0000402]; cytokine activity [GO:0005125]; DNA binding, bending [GO:0008301]; double-stranded DNA binding [GO:0003690]; four-way junction DNA binding [GO:0000400]; glycolipid binding [GO:0051861]; heparin binding [GO:0008201]; open form four-way junction DNA binding [GO:0000401]; peptide binding [GO:0042277]; protein dimerization activity [GO:0046983]; RAGE receptor binding [GO:0050786]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription factor binding [GO:0008134]; actin cytoskeleton reorganization [GO:0031532]; activation of innate immune response [GO:0002218]; adaptive immune response [GO:0002250]; apoptotic cell clearance [GO:0043277]; autophagy [GO:0006914]; cell chemotaxis [GO:0060326]; cell morphogenesis [GO:0000902]; cellular response to interleukin-1 [GO:0071347]; chemotaxis [GO:0006935]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; DNA geometric change [GO:0032392]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; male-specific defense response to bacterium [GO:0050831]; myoblast proliferation [GO:0051450]; negative regulation of DNA replication [GO:0008156]; nervous system development [GO:0007399]; neuron projection development [GO:0031175]; neutrophil clearance [GO:0097350]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA ligation [GO:0051106]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-1 secretion [GO:0050716]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage inflammatory protein 1 alpha production [GO:0071642]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of myeloid cell apoptotic process [GO:0033034]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of inflammatory response [GO:0050727]; regulation of signaling receptor activity [GO:0010469]; regulation of T cell mediated immune response to tumor cell [GO:0002840]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to insulin [GO:0032868]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]	chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	actin cytoskeleton reorganization [GO:0031532]; activation of innate immune response [GO:0002218]; adaptive immune response [GO:0002250]; apoptotic cell clearance [GO:0043277]; autophagy [GO:0006914]; cell chemotaxis [GO:0060326]; cell morphogenesis [GO:0000902]; cellular response to interleukin-1 [GO:0071347]; chemotaxis [GO:0006935]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; DNA geometric change [GO:0032392]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; male-specific defense response to bacterium [GO:0050831]; myoblast proliferation [GO:0051450]; negative regulation of DNA replication [GO:0008156]; nervous system development [GO:0007399]; neuron projection development [GO:0031175]; neutrophil clearance [GO:0097350]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA ligation [GO:0051106]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-1 secretion [GO:0050716]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage inflammatory protein 1 alpha production [GO:0071642]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of myeloid cell apoptotic process [GO:0033034]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of inflammatory response [GO:0050727]; regulation of signaling receptor activity [GO:0010469]; regulation of T cell mediated immune response to tumor cell [GO:0002840]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to insulin [GO:0032868]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]	5S rRNA binding [GO:0008097]; bent DNA binding [GO:0003681]; bubble DNA binding [GO:0000405]; crossed form four-way junction DNA binding [GO:0000402]; cytokine activity [GO:0005125]; DNA binding, bending [GO:0008301]; double-stranded DNA binding [GO:0003690]; four-way junction DNA binding [GO:0000400]; glycolipid binding [GO:0051861]; heparin binding [GO:0008201]; open form four-way junction DNA binding [GO:0000401]; peptide binding [GO:0042277]; protein dimerization activity [GO:0046983]; RAGE receptor binding [GO:0050786]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription factor binding [GO:0008134]
d1qrvb__d2gzka1__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]; chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; calmodulin binding [GO:0005516]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; transcription factor binding [GO:0008134]; cell differentiation [GO:0030154]; male sex determination [GO:0030238]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of male gonad development [GO:2000020]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; sex differentiation [GO:0007548]	chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	cell differentiation [GO:0030154]; male sex determination [GO:0030238]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of male gonad development [GO:2000020]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; sex differentiation [GO:0007548]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]	calmodulin binding [GO:0005516]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; transcription factor binding [GO:0008134]
d1qrzc__d1brup___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; other organism cell membrane [GO:0044218]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; Schaffer collateral - CA1 synapse [GO:0098685]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; kinase binding [GO:0019900]; proteasome core complex binding [GO:1904854]; protein antigen binding [GO:1990405]; protein domain specific binding [GO:0019904]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; extracellular matrix disassembly [GO:0022617]; fibrinolysis [GO:0042730]; interaction with symbiont [GO:0051702]; interaction with symbiont via secreted substance [GO:0052213]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of fibrinolysis [GO:0051918]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trophoblast giant cell differentiation [GO:0060707]	extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; extracellular matrix disassembly [GO:0022617]; fibrinolysis [GO:0042730]; interaction with symbiont [GO:0051702]; interaction with symbiont via secreted substance [GO:0052213]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of fibrinolysis [GO:0051918]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trophoblast giant cell differentiation [GO:0060707]	proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; other organism cell membrane [GO:0044218]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; Schaffer collateral - CA1 synapse [GO:0098685]	extracellular space [GO:0005615]	apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; kinase binding [GO:0019900]; proteasome core complex binding [GO:1904854]; protein antigen binding [GO:1990405]; protein domain specific binding [GO:0019904]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	serine-type endopeptidase activity [GO:0004252]
d1qs1a2_d2paxa2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; pathogenesis [GO:0009405]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA binding [GO:0003677]; NAD binding [GO:0051287]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]; ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	pathogenesis [GO:0009405]	ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	extracellular region [GO:0005576]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]	nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]
d1qs1b2_d5a00a2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; pathogenesis [GO:0009405]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1qs1c1_d1efya2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; pathogenesis [GO:0009405]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA binding [GO:0003677]; NAD binding [GO:0051287]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]; ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	pathogenesis [GO:0009405]	ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	extracellular region [GO:0005576]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]	nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]
d1qs1c1_d2c8fg___1			Firmicutes		extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	transferase activity, transferring pentosyl groups [GO:0016763]
d1qs1d2_d2c8ga___1			Firmicutes		extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	transferase activity, transferring pentosyl groups [GO:0016763]
d1qs2a1_d4hhzc2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; pathogenesis [GO:0009405]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1qs5a__d5jgua___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1qs8b__d3ndxa___1			Apicomplexa		integral component of membrane [GO:0016021]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	integral component of membrane [GO:0016021]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1qsaa2_d5b05a___1		Metazoa	Proteobacteria	Chordata	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; peptidoglycan-based cell wall [GO:0009274]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; lyase activity [GO:0016829]; lytic endotransglycosylase activity [GO:0008932]; lytic transglycosylase activity [GO:0008933]; cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; peptidoglycan-based cell wall [GO:0009274]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; lyase activity [GO:0016829]; lytic endotransglycosylase activity [GO:0008932]; lytic transglycosylase activity [GO:0008933]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1qsea1_d1t22b___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1qsed1_d3uypa1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1qsee2_d4rzce___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1qsfa2_d5laxc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d1qsfd1_d5fhal1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1qsfe2_d3ov6a3__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1qsga__d1v9la1__1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; membrane [GO:0016020]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1qsga__d2x86m___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; membrane [GO:0016020]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]
d1qsgc__d2yz7c___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]; membrane [GO:0016020]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]
d1qsge__d3wtbf___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	oxidoreductase activity [GO:0016491]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]; membrane [GO:0016020]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	oxidoreductase activity [GO:0016491]
d1qsgh__d2nu6a1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d1qshc__d5b13l___1	Metazoa		Chordata	Rhodophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1qsja__d2onha1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular space [GO:0005615]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; cofactor binding [GO:0048037]; endopeptidase inhibitor activity [GO:0004866]; lipid binding [GO:0008289]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; fatty acid metabolic process [GO:0006631]; inflammatory response [GO:0006954]; positive regulation of developmental growth [GO:0048639]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of protein phosphorylation [GO:0001934]; regulation of triglyceride biosynthetic process [GO:0010866]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to glucocorticoid [GO:0051384]; response to magnesium ion [GO:0032026]; response to progesterone [GO:0032570]; tolerance induction [GO:0002507]	magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; fatty acid metabolic process [GO:0006631]; inflammatory response [GO:0006954]; positive regulation of developmental growth [GO:0048639]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of protein phosphorylation [GO:0001934]; regulation of triglyceride biosynthetic process [GO:0010866]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to glucocorticoid [GO:0051384]; response to magnesium ion [GO:0032026]; response to progesterone [GO:0032570]; tolerance induction [GO:0002507]		extracellular space [GO:0005615]		C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; cofactor binding [GO:0048037]; endopeptidase inhibitor activity [GO:0004866]; lipid binding [GO:0008289]	magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d1qsjd__d4fjqa1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular space [GO:0005615]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; cofactor binding [GO:0048037]; endopeptidase inhibitor activity [GO:0004866]; lipid binding [GO:0008289]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; fatty acid metabolic process [GO:0006631]; inflammatory response [GO:0006954]; positive regulation of developmental growth [GO:0048639]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of protein phosphorylation [GO:0001934]; regulation of triglyceride biosynthetic process [GO:0010866]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to glucocorticoid [GO:0051384]; response to magnesium ion [GO:0032026]; response to progesterone [GO:0032570]; tolerance induction [GO:0002507]	amorpha-4,11-diene synthase activity [GO:0034006]; magnesium ion binding [GO:0000287]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; fatty acid metabolic process [GO:0006631]; inflammatory response [GO:0006954]; positive regulation of developmental growth [GO:0048639]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of protein phosphorylation [GO:0001934]; regulation of triglyceride biosynthetic process [GO:0010866]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to glucocorticoid [GO:0051384]; response to magnesium ion [GO:0032026]; response to progesterone [GO:0032570]; tolerance induction [GO:0002507]		extracellular space [GO:0005615]		C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; cofactor binding [GO:0048037]; endopeptidase inhibitor activity [GO:0004866]; lipid binding [GO:0008289]	amorpha-4,11-diene synthase activity [GO:0034006]; magnesium ion binding [GO:0000287]
d1qsla1_d4khna1__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; 3'-5' exonuclease activity [GO:0008408]; 5'-3' exonuclease activity [GO:0008409]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	base-excision repair [GO:0006284]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		3'-5' exonuclease activity [GO:0008408]; 5'-3' exonuclease activity [GO:0008409]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1qsma__d2i00a2__1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; histone acetyltransferase activity [GO:0004402]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]; protein acetylation [GO:0006473]	N-acetyltransferase activity [GO:0008080]	protein acetylation [GO:0006473]		cytoplasm [GO:0005737]		histone acetyltransferase activity [GO:0004402]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]
d1qsma__d2j8ma___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; histone acetyltransferase activity [GO:0004402]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]; protein acetylation [GO:0006473]	N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	protein acetylation [GO:0006473]		cytoplasm [GO:0005737]		histone acetyltransferase activity [GO:0004402]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1qsmb__d5t7ed___1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; histone acetyltransferase activity [GO:0004402]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]; protein acetylation [GO:0006473]	N-acetyltransferase activity [GO:0008080]; phosphinothricin N-acetyltransferase activity [GO:0102971]; response to antibiotic [GO:0046677]; response to herbicide [GO:0009635]	protein acetylation [GO:0006473]	response to antibiotic [GO:0046677]; response to herbicide [GO:0009635]	cytoplasm [GO:0005737]		histone acetyltransferase activity [GO:0004402]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]; phosphinothricin N-acetyltransferase activity [GO:0102971]
d1qsna1_d4ag7b___1	Fungi	Metazoa	Ascomycota	Nematoda (roundworms)	CENP-A containing nucleosome [GO:0043505]; nuclear nucleosome [GO:0000788]; nucleus [GO:0005634]; replication fork protection complex [GO:0031298]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin assembly or disassembly [GO:0006333]; global genome nucleotide-excision repair [GO:0070911]; rRNA transcription [GO:0009303]; sexual sporulation resulting in formation of a cellular spore [GO:0043935]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	chromatin assembly or disassembly [GO:0006333]; global genome nucleotide-excision repair [GO:0070911]; rRNA transcription [GO:0009303]; sexual sporulation resulting in formation of a cellular spore [GO:0043935]	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	CENP-A containing nucleosome [GO:0043505]; nuclear nucleosome [GO:0000788]; nucleus [GO:0005634]; replication fork protection complex [GO:0031298]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]
d1qsoa__d2jlmc___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; histone acetyltransferase activity [GO:0004402]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]; protein acetylation [GO:0006473]	N-acetyltransferase activity [GO:0008080]	protein acetylation [GO:0006473]		cytoplasm [GO:0005737]		histone acetyltransferase activity [GO:0004402]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]
d1qspb__d4g78a1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; nucleus [GO:0005634]; histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]; osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; cytokinin-activated signaling pathway [GO:0009736]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	cytokinin-activated signaling pathway [GO:0009736]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]	histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]
d1qsqa__d4hpia___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1qsra1_d3r95a___1			Ciliophora	Proteobacteria	histone acetyltransferase activity [GO:0004402]	N-acetyltransferase activity [GO:0008080]; nucleotide binding [GO:0000166]					histone acetyltransferase activity [GO:0004402]	N-acetyltransferase activity [GO:0008080]; nucleotide binding [GO:0000166]
d1qswc__d3wpla___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1qsya1_d4ahca1__1			Deinococcus-Thermus	Euryarchaeota	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; endonuclease activity [GO:0004519]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	DNA replication [GO:0006260]			DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; endonuclease activity [GO:0004519]; nucleotide binding [GO:0000166]
d1qsza__d5n4gl2__1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]		blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]	
d1qt1a__d1bxcb___1			Actinobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1qt1b__d1de5b___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; L-rhamnose isomerase activity [GO:0008740]; manganese ion binding [GO:0030145]; rhamnose binding [GO:0033296]; zinc ion binding [GO:0008270]; L-lyxose metabolic process [GO:0019324]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]	D-xylose metabolic process [GO:0042732]	L-lyxose metabolic process [GO:0019324]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	identical protein binding [GO:0042802]; L-rhamnose isomerase activity [GO:0008740]; manganese ion binding [GO:0030145]; rhamnose binding [GO:0033296]; zinc ion binding [GO:0008270]
d1qtca__d1bvxa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1qtca__d3ht9a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1qtda__d111la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1qtha__d228la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1qthb__d1l15a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1qthb__d2meab___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1qtoa__d1ewjh___1			Actinobacteria	Proteobacteria	drug binding [GO:0008144]; response to antibiotic [GO:0046677]	drug binding [GO:0008144]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]			drug binding [GO:0008144]	drug binding [GO:0008144]
d1qtqa2_d3x1jc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; [citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	coenzyme A biosynthetic process [GO:0015937]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]	[citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1qtra__d5iq3c___1			Proteobacteria		cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]	hydrolase activity [GO:0016787]			cytoplasm [GO:0005737]		aminopeptidase activity [GO:0004177]	hydrolase activity [GO:0016787]
d1qtsa1_d1gyua1__1	Metazoa	Metazoa	Chordata	Chordata	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]; collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]	clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]	collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]
d1qtva__d212la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1qtwa__d5ximc___1			Proteobacteria	Actinobacteria	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	D-xylose metabolic process [GO:0042732]		cytoplasm [GO:0005737]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1qtyt__d1epfc1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]	cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]
d1qtyt__d1j5oh1__1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1qtyx__d3d5of1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1qtza__d1ljia___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1quea2_d1fdra2__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; FAD binding [GO:0071949]; ferredoxin-NADP+ reductase activity [GO:0004324]; oxidoreductase activity [GO:0016491]; fructose catabolic process [GO:0006001]; iron-sulfur cluster assembly [GO:0016226]; response to drug [GO:0042493]; response to superoxide [GO:0000303]	oxidation-reduction process [GO:0055114]	fructose catabolic process [GO:0006001]; iron-sulfur cluster assembly [GO:0016226]; response to drug [GO:0042493]; response to superoxide [GO:0000303]	phycobilisome [GO:0030089]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	FAD binding [GO:0071949]; ferredoxin-NADP+ reductase activity [GO:0004324]; oxidoreductase activity [GO:0016491]
d1quia__d1o7tg___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	metal ion binding [GO:0046872]; transmembrane transport [GO:0055085]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]		phosphate ion binding [GO:0042301]	metal ion binding [GO:0046872]
d1quka__d5um2a1__1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	ATPase-coupled sulfate transmembrane transporter activity [GO:0015419]; sulfur compound binding [GO:1901681]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]		phosphate ion binding [GO:0042301]	ATPase-coupled sulfate transmembrane transporter activity [GO:0015419]; sulfur compound binding [GO:1901681]
d1quma__d1xp3a1__1			Proteobacteria	Firmicutes	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; zinc ion binding [GO:0008270]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	DNA repair [GO:0006281]			deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; zinc ion binding [GO:0008270]
d1qunb1_d2jknc1__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		host cell membrane [GO:0033644]; pilus [GO:0009289]	pilus [GO:0009289]	mannose binding [GO:0005537]	
d1qunb2_d1r17a2__1			Proteobacteria	Firmicutes	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	host cell membrane [GO:0033644]; pilus [GO:0009289]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	mannose binding [GO:0005537]	metal ion binding [GO:0046872]
d1qunj1_d4z3fa1__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1qunl2_d1ut2i___1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		host cell membrane [GO:0033644]; pilus [GO:0009289]	pilus [GO:0009289]	mannose binding [GO:0005537]	
d1quqd__d1krsa___1	Metazoa		Chordata	Proteobacteria	DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; single-stranded DNA binding [GO:0003697]; base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861]	cytosol [GO:0005829]; membrane [GO:0016020]	damaged DNA binding [GO:0003684]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]
d1qv6b2_d1a71b2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]	cytosol [GO:0005829]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1qv6b2_d3ufxh1__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; tricarboxylic acid cycle [GO:0006099]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]
d1qv7a2_d2xxja1__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	L-lactate dehydrogenase activity [GO:0004459]
d1qvcb__d5xgta___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]	single-stranded DNA binding [GO:0003697]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	cytosol [GO:0005829]		enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]	single-stranded DNA binding [GO:0003697]
d1qvea1_d1t92a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; pilus [GO:0009289]; glycosphingolipid binding [GO:0043208]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	type II protein secretion system complex [GO:0015627]; protein secretion by the type II secretion system [GO:0015628]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	protein secretion by the type II secretion system [GO:0015628]	periplasmic space [GO:0042597]; pilus [GO:0009289]	type II protein secretion system complex [GO:0015627]	glycosphingolipid binding [GO:0043208]	
d1qveb1_d1x6pa2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; pilus [GO:0009289]; glycosphingolipid binding [GO:0043208]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	pilus [GO:0009289]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]	periplasmic space [GO:0042597]; pilus [GO:0009289]	pilus [GO:0009289]	glycosphingolipid binding [GO:0043208]	
d1qvfr__d1ffkp___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1qvge2_d1njig1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1qvgj__d2gyci1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1qvoa1_d1m6ob___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1qvoa2_d1a6za2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1qvob1_d3kaaa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell junction [GO:0030054]; cell surface [GO:0009986]; early endosome [GO:0005769]; extracellular region [GO:0005576]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; mediator complex [GO:0016592]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; adaptive immune response [GO:0002250]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage activation involved in immune response [GO:0002281]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte colony-stimulating factor production [GO:0071656]; negative regulation of immune response to tumor cell [GO:0002838]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of interleukin-3 production [GO:0032712]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 1 type immune response [GO:0002826]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type I interferon production [GO:0032480]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of macrophage activation [GO:0043032]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of tolerance induction dependent upon immune response [GO:0002652]; regulation of transcription by RNA polymerase II [GO:0006357]; toll-like receptor 3 signaling pathway [GO:0034138]; toll-like receptor 7 signaling pathway [GO:0034154]; toll-like receptor 9 signaling pathway [GO:0034162]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage activation involved in immune response [GO:0002281]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte colony-stimulating factor production [GO:0071656]; negative regulation of immune response to tumor cell [GO:0002838]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of interleukin-3 production [GO:0032712]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 1 type immune response [GO:0002826]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type I interferon production [GO:0032480]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of macrophage activation [GO:0043032]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of tolerance induction dependent upon immune response [GO:0002652]; regulation of transcription by RNA polymerase II [GO:0006357]; toll-like receptor 3 signaling pathway [GO:0034138]; toll-like receptor 7 signaling pathway [GO:0034154]; toll-like receptor 9 signaling pathway [GO:0034162]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell junction [GO:0030054]; cell surface [GO:0009986]; early endosome [GO:0005769]; extracellular region [GO:0005576]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; mediator complex [GO:0016592]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]
d1qvod2_d1h15a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d1qvoe1_d1n5ag1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1qvtb1_d3sfia1__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d1qvud1_d2lfba___1		Metazoa	Firmicutes	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; photoreceptor outer segment [GO:0001750]; pronucleus [GO:0045120]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; double-stranded DNA binding [GO:0003690]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; bile acid and bile salt transport [GO:0015721]; bile acid biosynthetic process [GO:0006699]; blastocyst development [GO:0001824]; bone resorption [GO:0045453]; cholesterol metabolic process [GO:0008203]; chromatin remodeling [GO:0006338]; embryonic limb morphogenesis [GO:0030326]; endocrine pancreas development [GO:0031018]; fatty acid biosynthetic process [GO:0006633]; fatty acid transport [GO:0015908]; glucose homeostasis [GO:0042593]; glucose import [GO:0046323]; heme biosynthetic process [GO:0006783]; histone acetylation [GO:0016573]; insulin secretion [GO:0030073]; liver development [GO:0001889]; negative regulation of transcription by RNA polymerase II [GO:0000122]; paraxial mesoderm formation [GO:0048341]; placenta development [GO:0001890]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of hormone secretion [GO:0046883]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; renal glucose absorption [GO:0035623]; response to glucose [GO:0009749]; response to oxidative stress [GO:0006979]; reverse cholesterol transport [GO:0043691]; SMAD protein signal transduction [GO:0060395]; transcription by RNA polymerase II [GO:0006366]	negative regulation of transcription, DNA-templated [GO:0045892]	bile acid and bile salt transport [GO:0015721]; bile acid biosynthetic process [GO:0006699]; blastocyst development [GO:0001824]; bone resorption [GO:0045453]; cholesterol metabolic process [GO:0008203]; chromatin remodeling [GO:0006338]; embryonic limb morphogenesis [GO:0030326]; endocrine pancreas development [GO:0031018]; fatty acid biosynthetic process [GO:0006633]; fatty acid transport [GO:0015908]; glucose homeostasis [GO:0042593]; glucose import [GO:0046323]; heme biosynthetic process [GO:0006783]; histone acetylation [GO:0016573]; insulin secretion [GO:0030073]; liver development [GO:0001889]; negative regulation of transcription by RNA polymerase II [GO:0000122]; paraxial mesoderm formation [GO:0048341]; placenta development [GO:0001890]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hormone secretion [GO:0046883]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; renal glucose absorption [GO:0035623]; response to glucose [GO:0009749]; response to oxidative stress [GO:0006979]; reverse cholesterol transport [GO:0043691]; SMAD protein signal transduction [GO:0060395]; transcription by RNA polymerase II [GO:0006366]		cytoplasm [GO:0005737]; nucleus [GO:0005634]; photoreceptor outer segment [GO:0001750]; pronucleus [GO:0045120]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; double-stranded DNA binding [GO:0003690]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1qvud1_d2xpva1__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d1qvxa__d1pv3a1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]; actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]; actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]	ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]	ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]
d1qvyb__d1urzf1__1	Metazoa		Chordata		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1qvyd__d1doab___1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]
d1qw5b__d5g6da___1	Metazoa		Chordata	Firmicutes	cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; actin binding [GO:0003779]; arginine binding [GO:0034618]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; cAMP-dependent protein kinase regulator activity [GO:0008603]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; nitric-oxide synthase binding [GO:0050998]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tetrahydrobiopterin binding [GO:0034617]; arginine catabolic process [GO:0006527]; cellular response to cytokine stimulus [GO:0071345]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; circadian rhythm [GO:0007623]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; prostaglandin secretion [GO:0032310]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric-oxide synthase activity [GO:0004517]; nitric oxide biosynthetic process [GO:0006809]	arginine catabolic process [GO:0006527]; cellular response to cytokine stimulus [GO:0071345]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; circadian rhythm [GO:0007623]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; prostaglandin secretion [GO:0032310]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	nitric oxide biosynthetic process [GO:0006809]	cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]		actin binding [GO:0003779]; arginine binding [GO:0034618]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; cAMP-dependent protein kinase regulator activity [GO:0008603]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; nitric-oxide synthase binding [GO:0050998]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tetrahydrobiopterin binding [GO:0034617]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric-oxide synthase activity [GO:0004517]
d1qw8a2_d3mv043__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]	beta-galactosidase complex [GO:0009341]	alpha-L-arabinofuranosidase activity [GO:0046556]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1qw9b2_d4hoxa1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		alpha-L-arabinofuranosidase activity [GO:0046556]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d1qwjb__d1vzxa___1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; N-acylneuraminate cytidylyltransferase activity [GO:0008781]; CMP-N-acetylneuraminate biosynthetic process [GO:0006055]; N-acetylneuraminate metabolic process [GO:0006054]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	CMP-N-acetylneuraminate biosynthetic process [GO:0006055]; N-acetylneuraminate metabolic process [GO:0006054]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	nucleus [GO:0005634]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	N-acylneuraminate cytidylyltransferase activity [GO:0008781]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d1qwjc__d1g3ld___1	Metazoa		Chordata	Proteobacteria	nucleus [GO:0005634]; N-acylneuraminate cytidylyltransferase activity [GO:0008781]; CMP-N-acetylneuraminate biosynthetic process [GO:0006055]; N-acetylneuraminate metabolic process [GO:0006054]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	CMP-N-acetylneuraminate biosynthetic process [GO:0006055]; N-acetylneuraminate metabolic process [GO:0006054]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	nucleus [GO:0005634]		N-acylneuraminate cytidylyltransferase activity [GO:0008781]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1qwna3_d2cc0b___1	Metazoa		Arthropoda	Actinobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]
d1qwsd1_d1gpwd___1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; histidine biosynthetic process [GO:0000105]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	histidine biosynthetic process [GO:0000105]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]
d1qwta__d5jekb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]
d1qwua2_d3muy45__1	Metazoa		Arthropoda	Proteobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	beta-galactosidase complex [GO:0009341]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1qwua3_d2f7pa3__1	Metazoa	Metazoa	Arthropoda	Arthropoda	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1qx1a1_d1k1ya1__1	Metazoa		Arthropoda	Euryarchaeota	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]
d1qx1a2_d3vdaa5__1	Metazoa		Arthropoda	Proteobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	beta-galactosidase complex [GO:0009341]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1qx1a3_d1w1b1___1	Metazoa		Arthropoda	Firmicutes	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]; sporulation resulting in formation of a cellular spore [GO:0030435]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]; sporulation resulting in formation of a cellular spore [GO:0030435]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]
d1qx2a__d1cdna___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]			apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]
d1qx2b__d3icba___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]			apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]
d1qx4a2_d2qdxa2__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; mitochondrial outer membrane [GO:0005741]; ADP binding [GO:0043531]; AMP binding [GO:0016208]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; cholesterol biosynthetic process [GO:0006695]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]; cellular response to oxidative stress [GO:0034599]; heme catabolic process [GO:0042167]	cholesterol biosynthetic process [GO:0006695]	cellular response to oxidative stress [GO:0034599]; heme catabolic process [GO:0042167]	endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; mitochondrial outer membrane [GO:0005741]		ADP binding [GO:0043531]; AMP binding [GO:0016208]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1qx5d__d1djga1__1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]
d1qx5y__d2y5ib___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	calcium ion binding [GO:0005509]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]		adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]	calcium ion binding [GO:0005509]
d1qxea__d3gqpd___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1qxeb__d1w92a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1qxec__d1jl7a___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1qxed__d1glib___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1qxha__d2z9si___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]; heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d1qxha__d3i6ah1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1qxka__d4d3qa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; JUN kinase phosphatase activity [GO:0008579]; MAP-kinase scaffold activity [GO:0005078]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase activator activity [GO:0030295]; protein kinase inhibitor activity [GO:0004860]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase activity [GO:0045860]; regulation of MAP kinase activity [GO:0043405]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase activity [GO:0045860]; regulation of MAP kinase activity [GO:0043405]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	JUN kinase phosphatase activity [GO:0008579]; MAP-kinase scaffold activity [GO:0005078]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase activator activity [GO:0030295]; protein kinase inhibitor activity [GO:0004860]; protein tyrosine phosphatase activity [GO:0004725]
d1qxma1_d2d1za2__1				Actinobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	pathogenesis [GO:0009405]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]
d1qxsa2_d1rm4b2__1		Viridiplantae		Streptophyta	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glycosome [GO:0020015]	chloroplast [GO:0009507]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1qxsc2_d4r51b2__1					glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		glycosome [GO:0020015]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	
d1qxya__d4mata1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]	ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]
d1qy0a__d5khpc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone activity [GO:0005186]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to food [GO:0071240]; cellular response to lipid [GO:0071396]; cellular response to starvation [GO:0009267]; cellular response to testosterone stimulus [GO:0071394]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]; response to stilbenoid [GO:0035634]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	aerobic respiration [GO:0009060]; cellular response to food [GO:0071240]; cellular response to lipid [GO:0071396]; cellular response to starvation [GO:0009267]; cellular response to testosterone stimulus [GO:0071394]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]; response to stilbenoid [GO:0035634]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	insulin-activated receptor activity [GO:0005009]; pheromone activity [GO:0005186]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1qy2a__d1ftpb___1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone activity [GO:0005186]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to food [GO:0071240]; cellular response to lipid [GO:0071396]; cellular response to starvation [GO:0009267]; cellular response to testosterone stimulus [GO:0071394]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]; response to stilbenoid [GO:0035634]	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	aerobic respiration [GO:0009060]; cellular response to food [GO:0071240]; cellular response to lipid [GO:0071396]; cellular response to starvation [GO:0009267]; cellular response to testosterone stimulus [GO:0071394]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]; response to stilbenoid [GO:0035634]		cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	insulin-activated receptor activity [GO:0005009]; pheromone activity [GO:0005186]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	lipid binding [GO:0008289]
d1qyab1_d3ejxa1__1		Viridiplantae	Proteobacteria	Streptophyta	isomerase activity [GO:0016853]; biosynthetic process [GO:0009058]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	biosynthetic process [GO:0009058]	lysine biosynthetic process via diaminopimelate [GO:0009089]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]	isomerase activity [GO:0016853]	diaminopimelate epimerase activity [GO:0008837]
d1qyab2_d3ejxd1__1		Viridiplantae	Proteobacteria	Streptophyta	isomerase activity [GO:0016853]; biosynthetic process [GO:0009058]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	biosynthetic process [GO:0009058]	lysine biosynthetic process via diaminopimelate [GO:0009089]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]	isomerase activity [GO:0016853]	diaminopimelate epimerase activity [GO:0008837]
d1qycb__d3rwbb___1	Viridiplantae		Streptophyta	Proteobacteria	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor [GO:0050664]; lignan biosynthetic process [GO:0009807]	pyridoxal 4-dehydrogenase activity [GO:0050235]; vitamin B6 catabolic process [GO:0042820]	lignan biosynthetic process [GO:0009807]	vitamin B6 catabolic process [GO:0042820]			oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor [GO:0050664]	pyridoxal 4-dehydrogenase activity [GO:0050235]
d1qygh2_d3dbxb___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1qygh2_d5cbaa___1		Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d1qygl2_d3ojda1__1												
d1qyyg__d3kj4d___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; thrombin-activated receptor activity [GO:0015057]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; presynapse [GO:0098793]; chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; Roundabout binding [GO:0048495]; signaling receptor activity [GO:0038023]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; presynapse [GO:0098793]	thrombin-activated receptor activity [GO:0015057]	chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; Roundabout binding [GO:0048495]; signaling receptor activity [GO:0038023]
d1qz0a__d2fh7a2__1		Metazoa	Proteobacteria	Chordata	protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]	pathogenesis [GO:0009405]	cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]		axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	protein tyrosine phosphatase activity [GO:0004725]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]
d1qz1a1_d3ry4a1__1	Metazoa	Metazoa	Chordata	Chordata	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]	aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]	IgG binding [GO:0019864]
d1qz2a2_d2ki3a___1	Metazoa		Chordata	Apicomplexa	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein-containing complex localization [GO:0031503]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein-containing complex localization [GO:0031503]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]		axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]		ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1qz2b1_d4gcoa___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein-containing complex localization [GO:0031503]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	cytoplasm [GO:0005737]; ATPase inhibitor activity [GO:0042030]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; determination of adult lifespan [GO:0008340]; negative regulation of ATPase activity [GO:0032780]; reproduction [GO:0000003]; response to heat [GO:0009408]	androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein-containing complex localization [GO:0031503]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	determination of adult lifespan [GO:0008340]; negative regulation of ATPase activity [GO:0032780]; reproduction [GO:0000003]; response to heat [GO:0009408]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	ATPase inhibitor activity [GO:0042030]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]
d1qz2c2_d3o5ja___1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein-containing complex localization [GO:0031503]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein-containing complex localization [GO:0031503]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1qz5a2_d4bqza1__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adenosine-diphosphatase activity [GO:0043262]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	adenosine-diphosphatase activity [GO:0043262]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]
d1qz5a2_d5aqja1__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d1qz6a2_d4l3qa1__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]
d1qzfb1_d4eleb1__1			Apicomplexa	Firmicutes	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1qzfc1_d1dhfa___1		Metazoa	Apicomplexa	Chordata	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1qzfe2_d1njaa___1			Apicomplexa	Firmicutes	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]		cytoplasm [GO:0005737]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d1qzhb__d1ph4a3__1	Fungi		Ascomycota	Ciliophora	cytosol [GO:0005829]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]; nuclear telomeric heterochromatin [GO:0005724]; nucleus [GO:0005634]; shelterin complex [GO:0070187]; telomere cap complex [GO:0000782]; G-rich strand telomeric DNA binding [GO:0098505]; single-stranded telomeric DNA binding [GO:0043047]; telomerase inhibitor activity [GO:0010521]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]	telomere capping [GO:0016233]	cytosol [GO:0005829]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]; nuclear telomeric heterochromatin [GO:0005724]; nucleus [GO:0005634]; shelterin complex [GO:0070187]; telomere cap complex [GO:0000782]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	G-rich strand telomeric DNA binding [GO:0098505]; single-stranded telomeric DNA binding [GO:0043047]; telomerase inhibitor activity [GO:0010521]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1qzhc__d1i95q___1	Fungi		Ascomycota	Deinococcus-Thermus	cytosol [GO:0005829]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]; nuclear telomeric heterochromatin [GO:0005724]; nucleus [GO:0005634]; shelterin complex [GO:0070187]; telomere cap complex [GO:0000782]; G-rich strand telomeric DNA binding [GO:0098505]; single-stranded telomeric DNA binding [GO:0043047]; telomerase inhibitor activity [GO:0010521]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]	translation [GO:0006412]	cytosol [GO:0005829]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]; nuclear telomeric heterochromatin [GO:0005724]; nucleus [GO:0005634]; shelterin complex [GO:0070187]; telomere cap complex [GO:0000782]	ribosome [GO:0005840]	G-rich strand telomeric DNA binding [GO:0098505]; single-stranded telomeric DNA binding [GO:0043047]; telomerase inhibitor activity [GO:0010521]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1qzna__d4tf4b2__1			Firmicutes	Actinobacteria	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]			carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d1qzrb2_d1s16a2__1	Fungi		Ascomycota	Proteobacteria	DNA replication termination region [GO:0097047]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; synaptonemal complex [GO:0000795]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; chromatin assembly or disassembly [GO:0006333]; chromatin remodeling at centromere [GO:0031055]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA topological change [GO:0006265]; mitotic DNA integrity checkpoint [GO:0044774]; reciprocal meiotic recombination [GO:0007131]; regulation of mitotic recombination [GO:0000019]; replication fork progression beyond termination site [GO:0097046]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819]	chromosome [GO:0005694]; cytosol [GO:0005829]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; chromosome organization [GO:0051276]; DNA topological change [GO:0006265]; plasmid partitioning [GO:0030541]; response to antibiotic [GO:0046677]; sister chromatid cohesion [GO:0007062]	chromatin assembly or disassembly [GO:0006333]; chromatin remodeling at centromere [GO:0031055]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA topological change [GO:0006265]; mitotic DNA integrity checkpoint [GO:0044774]; reciprocal meiotic recombination [GO:0007131]; regulation of mitotic recombination [GO:0000019]; replication fork progression beyond termination site [GO:0097046]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819]	chromosome organization [GO:0051276]; DNA topological change [GO:0006265]; plasmid partitioning [GO:0030541]; response to antibiotic [GO:0046677]; sister chromatid cohesion [GO:0007062]	DNA replication termination region [GO:0097047]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; synaptonemal complex [GO:0000795]	chromosome [GO:0005694]; cytosol [GO:0005829]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d1qzrb2_d1us7a___1	Fungi	Fungi	Ascomycota	Ascomycota	DNA replication termination region [GO:0097047]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; synaptonemal complex [GO:0000795]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; chromatin assembly or disassembly [GO:0006333]; chromatin remodeling at centromere [GO:0031055]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA topological change [GO:0006265]; mitotic DNA integrity checkpoint [GO:0044774]; reciprocal meiotic recombination [GO:0007131]; regulation of mitotic recombination [GO:0000019]; replication fork progression beyond termination site [GO:0097046]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	chromatin assembly or disassembly [GO:0006333]; chromatin remodeling at centromere [GO:0031055]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA topological change [GO:0006265]; mitotic DNA integrity checkpoint [GO:0044774]; reciprocal meiotic recombination [GO:0007131]; regulation of mitotic recombination [GO:0000019]; replication fork progression beyond termination site [GO:0097046]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	DNA replication termination region [GO:0097047]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; synaptonemal complex [GO:0000795]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]
d1qzwe3_d4iola___1			Crenarchaeota	Firmicutes	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; tetrahydrofolate interconversion [GO:0035999]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	tetrahydrofolate interconversion [GO:0035999]	signal recognition particle [GO:0048500]		7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]
d1qzwg1_d2j7pb1__1			Crenarchaeota	Deinococcus-Thermus	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]	signal recognition particle [GO:0048500]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1qzxb3_d2pt7a___1			Crenarchaeota	Proteobacteria	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	type IV secretion system complex [GO:0043684]; nucleotide binding [GO:0000166]; secretion by the type IV secretion system [GO:0044097]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	secretion by the type IV secretion system [GO:0044097]	signal recognition particle [GO:0048500]	type IV secretion system complex [GO:0043684]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	nucleotide binding [GO:0000166]
d1r03a__d4toaw___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; nucleus [GO:0005634]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; nucleus [GO:0005634]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1r081__d1b35a___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1r083__d1ddla___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1r093__d1cwpb___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1r093__d4iv3c___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1r0aa1_d1jlba1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1r0al1_d3r06a1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d1r0al2_d1qaca___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]
d1r0ba1_d3r7db1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1r0ba2_d2fg6z2__1			Proteobacteria	Bacteroidetes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]
d1r0ba2_d4amua1__1			Proteobacteria	Tenericutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1r0bb1_d1raga1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1r0bc2_d4jfra1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1r0bd2_d4jhxa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1r0bf2_d2rgwe2__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1r0ca1_d2g7mx1__1			Proteobacteria	Bacteroidetes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; cellular amino acid metabolic process [GO:0006520]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]
d1r0cg1_d4amuc1__1			Proteobacteria	Tenericutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1r0kb1_d1t1sb1__1			Proteobacteria	Proteobacteria	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; metal ion binding [GO:0046872]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]			1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; metal ion binding [GO:0046872]; NADPH binding [GO:0070402]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]
d1r0kc1_d2eghb1__1			Proteobacteria	Proteobacteria	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; metal ion binding [GO:0046872]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]			1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; metal ion binding [GO:0046872]; NADPH binding [GO:0070402]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]
d1r0lb1_d1q0qa1__1			Proteobacteria	Proteobacteria	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; metal ion binding [GO:0046872]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]			1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; metal ion binding [GO:0046872]; NADPH binding [GO:0070402]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]
d1r0ld1_d1t1rb1__1			Proteobacteria	Proteobacteria	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; metal ion binding [GO:0046872]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]			1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; metal ion binding [GO:0046872]; NADPH binding [GO:0070402]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]
d1r0mb1_d1sjad1__1			Deinococcus-Thermus	Actinobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	menaquinone biosynthetic process [GO:0009234]	menaquinone biosynthetic process [GO:0009234]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d1r0md1_d1ec8c1__1			Deinococcus-Thermus	Proteobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	menaquinone biosynthetic process [GO:0009234]	D-glucarate catabolic process [GO:0042838]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d1r0re__d1duia___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1r0ta__d3sndb___1						cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]		cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1r0va2_d1r11a1__1			Euryarchaeota	Euryarchaeota	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]			lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]
d1r0vc3_d1a79d2__1			Euryarchaeota	Euryarchaeota	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	tRNA-intron endonuclease complex [GO:0000214]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; tRNA-type intron splice site recognition and cleavage [GO:0000379]	tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	tRNA-type intron splice site recognition and cleavage [GO:0000379]		tRNA-intron endonuclease complex [GO:0000214]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]
d1r11b1_d2gjwa2__1			Euryarchaeota	Euryarchaeota	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]			lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]
d1r11b2_d2gw6b2__1		Metazoa	Euryarchaeota	Chordata	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]		nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]	nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]
d1r13a1_d5jpva___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; asialoglycoprotein receptor activity [GO:0004873]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular response to extracellular stimulus [GO:0031668]; protein N-linked glycosylation via asparagine [GO:0018279]; receptor-mediated endocytosis [GO:0006898]; viral process [GO:0016032]	cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	cellular response to extracellular stimulus [GO:0031668]; protein N-linked glycosylation via asparagine [GO:0018279]; receptor-mediated endocytosis [GO:0006898]; viral process [GO:0016032]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]	asialoglycoprotein receptor activity [GO:0004873]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d1r14a1_d3wh2a___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; pattern recognition receptor activity [GO:0038187]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway [GO:0038094]; innate immune response [GO:0045087]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cytokine secretion [GO:0050715]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell differentiation involved in immune response [GO:0002292]	cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway [GO:0038094]; innate immune response [GO:0045087]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cytokine secretion [GO:0050715]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell differentiation involved in immune response [GO:0002292]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; pattern recognition receptor activity [GO:0038187]
d1r15g__d3dzhb___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d1r15g__d5bnia___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]; positive regulation of B cell proliferation [GO:0030890]	single fertilization [GO:0007338]	positive regulation of B cell proliferation [GO:0030890]	cytoplasmic vesicle [GO:0031410]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]
d1r17b2_d4xobe1__1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	host cell membrane [GO:0033644]; pilus [GO:0009289]	metal ion binding [GO:0046872]	mannose binding [GO:0005537]
d1r1a1__d4y5zk___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1r1ca__d1x9ra___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1r1cb__d1gw0a2__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	oxidation-reduction process [GO:0055114]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1r1cc__d1niba2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1r1cd__d2ppdc1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1r1ha__d2d1nb___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; brush border [GO:0005903]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; cardiolipin binding [GO:1901612]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; oligopeptidase activity [GO:0070012]; peptide binding [GO:0042277]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; aging [GO:0007568]; amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; learning or memory [GO:0007611]; lung development [GO:0030324]; neuropeptide processing [GO:0061837]; neutrophil degranulation [GO:0043312]; peptide metabolic process [GO:0006518]; placenta development [GO:0001890]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neurogenesis [GO:0050769]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	aging [GO:0007568]; amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; learning or memory [GO:0007611]; lung development [GO:0030324]; neuropeptide processing [GO:0061837]; neutrophil degranulation [GO:0043312]; peptide metabolic process [GO:0006518]; placenta development [GO:0001890]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neurogenesis [GO:0050769]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	axon [GO:0030424]; brush border [GO:0005903]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cardiolipin binding [GO:1901612]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; oligopeptidase activity [GO:0070012]; peptide binding [GO:0042277]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1r1ja__d4fvlb1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; brush border [GO:0005903]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; cardiolipin binding [GO:1901612]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; oligopeptidase activity [GO:0070012]; peptide binding [GO:0042277]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; aging [GO:0007568]; amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; learning or memory [GO:0007611]; lung development [GO:0030324]; neuropeptide processing [GO:0061837]; neutrophil degranulation [GO:0043312]; peptide metabolic process [GO:0006518]; placenta development [GO:0001890]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neurogenesis [GO:0050769]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	aging [GO:0007568]; amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; learning or memory [GO:0007611]; lung development [GO:0030324]; neuropeptide processing [GO:0061837]; neutrophil degranulation [GO:0043312]; peptide metabolic process [GO:0006518]; placenta development [GO:0001890]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neurogenesis [GO:0050769]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	axon [GO:0030424]; brush border [GO:0005903]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cardiolipin binding [GO:1901612]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; oligopeptidase activity [GO:0070012]; peptide binding [GO:0042277]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1r1nb__d5kcja___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; NMDA selective glutamate receptor complex [GO:0017146]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; glutamate-gated calcium ion channel activity [GO:0022849]; NMDA glutamate receptor activity [GO:0004972]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity [GO:0097202]; brain development [GO:0007420]; calcium ion transmembrane import into cytosol [GO:0097553]; chemical synaptic transmission [GO:0007268]; directional locomotion [GO:0033058]; dopamine metabolic process [GO:0042417]; excitatory chemical synaptic transmission [GO:0098976]; excitatory postsynaptic potential [GO:0060079]; glutamate receptor signaling pathway [GO:0007215]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of protein catabolic process [GO:0042177]; neurogenesis [GO:0022008]; positive regulation of apoptotic process [GO:0043065]; protein localization to postsynaptic membrane [GO:1903539]; regulation of NMDA receptor activity [GO:2000310]; regulation of synaptic plasticity [GO:0048167]; response to amphetamine [GO:0001975]; response to ethanol [GO:0045471]; response to wounding [GO:0009611]; sensory perception of pain [GO:0019233]; serotonin metabolic process [GO:0042428]; sleep [GO:0030431]; startle response [GO:0001964]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	activation of cysteine-type endopeptidase activity [GO:0097202]; brain development [GO:0007420]; calcium ion transmembrane import into cytosol [GO:0097553]; chemical synaptic transmission [GO:0007268]; directional locomotion [GO:0033058]; dopamine metabolic process [GO:0042417]; excitatory chemical synaptic transmission [GO:0098976]; excitatory postsynaptic potential [GO:0060079]; glutamate receptor signaling pathway [GO:0007215]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of protein catabolic process [GO:0042177]; neurogenesis [GO:0022008]; positive regulation of apoptotic process [GO:0043065]; protein localization to postsynaptic membrane [GO:1903539]; regulation of NMDA receptor activity [GO:2000310]; regulation of synaptic plasticity [GO:0048167]; response to amphetamine [GO:0001975]; response to ethanol [GO:0045471]; response to wounding [GO:0009611]; sensory perception of pain [GO:0019233]; serotonin metabolic process [GO:0042428]; sleep [GO:0030431]; startle response [GO:0001964]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542]	periplasmic space [GO:0042597]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; NMDA selective glutamate receptor complex [GO:0017146]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]	metal ion binding [GO:0046872]	amyloid-beta binding [GO:0001540]; glutamate-gated calcium ion channel activity [GO:0022849]; glutamate receptor activity [GO:0008066]; NMDA glutamate receptor activity [GO:0004972]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; zinc ion binding [GO:0008270]
d1r1ne__d5itob___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	nitrogen compound transport [GO:0071705]	periplasmic space [GO:0042597]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]	ligand-gated ion channel activity [GO:0015276]
d1r1nh__d2o7ub___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	periplasmic space [GO:0042597]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	metal ion binding [GO:0046872]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d1r1oc__d4cevc___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]
d1r1pd__d1ad5a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]		ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]
d1r1ra2_d2r1ra2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1r1rb2_d5a0ud___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	carbon-nitrogen lyase activity [GO:0016840]; choline catabolic process [GO:0042426]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	choline catabolic process [GO:0042426]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	carbon-nitrogen lyase activity [GO:0016840]
d1r1tb__d2fbia1__1			Cyanobacteria	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]	DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]		negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]	DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]
d1r1ua__d1u2wb___1			Firmicutes	Firmicutes	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; response to cadmium ion [GO:0046686]		response to cadmium ion [GO:0046686]			DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]
d1r1ud__d2ve9c___1			Firmicutes	Proteobacteria	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to antibiotic [GO:0071236]; chromosome segregation [GO:0007059]		cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to antibiotic [GO:0071236]; chromosome segregation [GO:0007059]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; DNA binding [GO:0003677]
d1r1vb__d2h6bb1__1			Firmicutes	Firmicutes	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]		regulation of transcription, DNA-templated [GO:0006355]			DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d1r1ya__d1rpsa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1r1ya__d3wcvg___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1r1yb__d2auqa___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1r1yd__d1rqad___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1r21a__d2xt9b___1	Metazoa		Chordata		chromosome [GO:0005694]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; regulation of chromatin organization [GO:1902275]; regulation of chromosome segregation [GO:0051983]; regulation of mitotic nuclear division [GO:0007088]		cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; regulation of chromatin organization [GO:1902275]; regulation of chromosome segregation [GO:0051983]; regulation of mitotic nuclear division [GO:0007088]		chromosome [GO:0005694]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]	
d1r23b__d5e8gb___1		Metazoa	Cyanobacteria	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; animal organ morphogenesis [GO:0009887]; blood circulation [GO:0008015]; cell differentiation [GO:0030154]; hemostasis [GO:0007599]; megakaryocyte development [GO:0035855]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]		animal organ morphogenesis [GO:0009887]; blood circulation [GO:0008015]; cell differentiation [GO:0030154]; hemostasis [GO:0007599]; megakaryocyte development [GO:0035855]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]		cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d1r24a2_d1bfog2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1r24b2_d1lnuh1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d1r24c1_d5u1rb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1r24d1_d4d9lo1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1r24d2_d4ei5h1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1r27a1_d3i9vc4__1			Proteobacteria	Deinococcus-Thermus	intrinsic component of membrane [GO:0031224]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; membrane [GO:0016020]; NarGHI complex [GO:0044799]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]; nitrate metabolic process [GO:0042126]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]; nitrate metabolic process [GO:0042126]		intrinsic component of membrane [GO:0031224]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; membrane [GO:0016020]; NarGHI complex [GO:0044799]	plasma membrane [GO:0005886]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]	quinone binding [GO:0048038]
d1r27b__d1vlfv2__1			Proteobacteria		intrinsic component of membrane [GO:0031224]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; membrane [GO:0016020]; NarGHI complex [GO:0044799]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]; nitrate metabolic process [GO:0042126]		anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]; nitrate metabolic process [GO:0042126]		intrinsic component of membrane [GO:0031224]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; membrane [GO:0016020]; NarGHI complex [GO:0044799]		3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]	
d1r27c1_d3cf1c1__1		Metazoa	Proteobacteria	Chordata	intrinsic component of membrane [GO:0031224]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; membrane [GO:0016020]; NarGHI complex [GO:0044799]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]; nitrate metabolic process [GO:0042126]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]; nitrate metabolic process [GO:0042126]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	intrinsic component of membrane [GO:0031224]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; membrane [GO:0016020]; NarGHI complex [GO:0044799]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1r2ch1_d3t6eh2__1			Proteobacteria	Proteobacteria	plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1r2fa__d1fzid___1			Proteobacteria	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	ribonucleoside-diphosphate reductase complex [GO:0005971]		metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1r2fa__d1vlgg___1			Proteobacteria	Thermotogae	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1r2fb__d2jd7h___1			Proteobacteria	Euryarchaeota	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]
d1r2sc__d2vekb___1	Metazoa		Chordata		cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	triose-phosphate isomerase activity [GO:0004807]
d1r2sd__d5i3kc___1	Metazoa		Chordata		cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	triose-phosphate isomerase activity [GO:0004807]
d1r2ta__d2velb___1	Metazoa		Chordata		cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	triose-phosphate isomerase activity [GO:0004807]
d1r2ua__d2wc8d1__1	Metazoa	Metazoa	Chordata	Chordata	myofilament [GO:0036379]; calcium ion binding [GO:0005509]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]		antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	myofilament [GO:0036379]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d1r2va4_d1x6na3__1				Proteobacteria		chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]				chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d1r2za2_d3sasa1__1			Firmicutes	Firmicutes	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]			class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]
d1r30a__d1tv8b___1			Proteobacteria	Firmicutes	2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; biotin synthase activity [GO:0004076]; iron ion binding [GO:0005506]; biotin biosynthetic process [GO:0009102]	molybdopterin synthase complex [GO:0019008]; 4 iron, 4 sulfur cluster binding [GO:0051539]; GTP 3',8'-cyclase activity [GO:0061798]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; S-adenosyl-L-methionine binding [GO:1904047]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	biotin biosynthetic process [GO:0009102]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]		molybdopterin synthase complex [GO:0019008]	2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; biotin synthase activity [GO:0004076]; iron ion binding [GO:0005506]	4 iron, 4 sulfur cluster binding [GO:0051539]; GTP 3',8'-cyclase activity [GO:0061798]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; S-adenosyl-L-methionine binding [GO:1904047]
d1r33a2_d3t0db5__1	Metazoa		Arthropoda	Proteobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	beta-galactosidase complex [GO:0009341]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1r36a__d3wtsc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune system process [GO:0002376]; negative regulation of cell cycle [GO:0045786]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune system process [GO:0002376]; negative regulation of cell cycle [GO:0045786]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]
d1r37a2_d5i7fc___1			Crenarchaeota	Proteobacteria	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]			alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d1r37b2_d4aj4b1__1		Metazoa	Crenarchaeota	Chordata	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		cytoplasm [GO:0005737]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1r3hb__d1ay1h1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1r3hd__d1mclb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1r3hf__d2w9lz___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1r3hh__d3gjea1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1r3ih1_d1kfal2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1r3ih1_d2vitb1__1	Metazoa		Chordata	Negarnaviricota	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	host cell surface receptor binding [GO:0046789]
d1r3il1_d1jguh1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1r3il1_d2ifga2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]
d1r3il2_d5o4ea2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1r3ja1_d5hyib1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	voltage-gated potassium channel complex [GO:0008076]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1r3ja2_d1yylh1__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	voltage-gated potassium channel complex [GO:0008076]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	structural molecule activity [GO:0005198]
d1r3jb1_d4ozge1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	voltage-gated potassium channel complex [GO:0008076]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1r3ka1_d1f3dj1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	metal ion binding [GO:0046872]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d1r3kb1_d5a16d1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1r3kb2_d4wo4a2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1r3la1_d1bfoa2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1r3lb2_d4h8wc2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	structural molecule activity [GO:0005198]
d1r3nc2_d1vixa2__1	Fungi		Ascomycota	Proteobacteria	beta-ureidopropionase activity [GO:0003837]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [GO:0016813]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; metallopeptidase activity [GO:0008237]; tripeptide aminopeptidase activity [GO:0045148]; zinc ion binding [GO:0008270]; peptide catabolic process [GO:0043171]; peptide metabolic process [GO:0006518]		peptide catabolic process [GO:0043171]; peptide metabolic process [GO:0006518]		cytosol [GO:0005829]	beta-ureidopropionase activity [GO:0003837]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [GO:0016813]; metal ion binding [GO:0046872]	metallopeptidase activity [GO:0008237]; tripeptide aminopeptidase activity [GO:0045148]; zinc ion binding [GO:0008270]
d1r3ne2_d1vgya2__1	Fungi		Ascomycota	Proteobacteria	beta-ureidopropionase activity [GO:0003837]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [GO:0016813]; metal ion binding [GO:0046872]	acetylornithine deacetylase activity [GO:0008777]; cobalt ion binding [GO:0050897]; succinyl-diaminopimelate desuccinylase activity [GO:0009014]; zinc ion binding [GO:0008270]; arginine biosynthetic process [GO:0006526]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		arginine biosynthetic process [GO:0006526]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]			beta-ureidopropionase activity [GO:0003837]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [GO:0016813]; metal ion binding [GO:0046872]	acetylornithine deacetylase activity [GO:0008777]; cobalt ion binding [GO:0050897]; succinyl-diaminopimelate desuccinylase activity [GO:0009014]; zinc ion binding [GO:0008270]
d1r3ra__d3cyva___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uroporphyrinogen decarboxylase activity [GO:0004853]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]; uroporphyrinogen decarboxylase activity [GO:0004853]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	uroporphyrinogen decarboxylase activity [GO:0004853]	uroporphyrinogen decarboxylase activity [GO:0004853]
d1r3ua__d1xtua___1			Firmicutes	Crenarchaeota	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytoplasm [GO:0005737]		guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]
d1r3ub__d3hvua1__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1r44d__d4c4nb___1		Metazoa	Firmicutes	Chordata	dipeptidase activity [GO:0016805]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; cell wall organization [GO:0071555]; response to antibiotic [GO:0046677]	axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]; transport vesicle [GO:0030133]; calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; laminin-1 binding [GO:0043237]; patched binding [GO:0005113]; zinc ion binding [GO:0008270]; anatomical structure development [GO:0048856]; anatomical structure formation involved in morphogenesis [GO:0048646]; androgen metabolic process [GO:0008209]; angiogenesis [GO:0001525]; animal organ formation [GO:0048645]; anterior/posterior pattern specification [GO:0009952]; apoptotic signaling pathway [GO:0097190]; artery development [GO:0060840]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; blood coagulation [GO:0007596]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bud outgrowth involved in lung branching [GO:0060447]; camera-type eye development [GO:0043010]; canonical Wnt signaling pathway [GO:0060070]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell development [GO:0048468]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cell proliferation in external granule layer [GO:0021924]; cell-cell signaling [GO:0007267]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; cerebellar granule cell precursor proliferation [GO:0021930]; commissural neuron axon guidance [GO:0071679]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; determination of left/right symmetry [GO:0007368]; developmental growth [GO:0048589]; digestive tract mesoderm development [GO:0007502]; digestive tract morphogenesis [GO:0048546]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic morphogenesis [GO:0048598]; embryonic organ development [GO:0048568]; embryonic skeletal system development [GO:0048706]; endocytosis [GO:0006897]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; epithelial-mesenchymal cell signaling [GO:0060684]; epithelial-mesenchymal signaling involved in prostate gland development [GO:0060738]; establishment of cell polarity [GO:0030010]; forebrain development [GO:0030900]; forebrain regionalization [GO:0021871]; formation of anatomical boundary [GO:0048859]; fungiform papilla development [GO:0061196]; fungiform papilla formation [GO:0061198]; fungiform papilla morphogenesis [GO:0061197]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; inner ear development [GO:0048839]; intein-mediated protein splicing [GO:0016539]; intermediate filament organization [GO:0045109]; kidney development [GO:0001822]; left lung development [GO:0060459]; limb bud formation [GO:0060174]; limb development [GO:0060173]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung lobe morphogenesis [GO:0060463]; lung morphogenesis [GO:0060425]; lung-associated mesenchyme development [GO:0060484]; lymphoid progenitor cell differentiation [GO:0002320]; male genitalia development [GO:0030539]; male genitalia morphogenesis [GO:0048808]; mesenchymal cell proliferation [GO:0010463]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal smoothened signaling pathway involved in prostate gland development [GO:0060783]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephros development [GO:0001656]; midbrain development [GO:0030901]; myoblast differentiation [GO:0045445]; myotube differentiation [GO:0014902]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of gene expression [GO:0010629]; negative regulation of kidney smooth muscle cell differentiation [GO:2000357]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of neuron death [GO:1901215]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of ureter smooth muscle cell differentiation [GO:2000062]; negative regulation of Wnt signaling pathway [GO:0030178]; negative thymic T cell selection [GO:0045060]; neural crest cell migration [GO:0001755]; neural tube formation [GO:0001841]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; odontogenesis [GO:0042476]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; osteoblast development [GO:0002076]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; polarity specification of anterior/posterior axis [GO:0009949]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of gene expression [GO:0010628]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of kidney smooth muscle cell differentiation [GO:2000358]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mesenchymal cell proliferation involved in ureter development [GO:2000729]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neurotrophin production [GO:0032901]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; positive regulation of penile erection [GO:0060406]; positive regulation of photoreceptor cell differentiation [GO:0046534]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sclerotome development [GO:0061189]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ureter smooth muscle cell differentiation [GO:2000063]; positive regulation of Wnt signaling pathway [GO:0030177]; positive thymic T cell selection [GO:0045059]; primary prostatic bud elongation [GO:0060516]; prostate epithelial cord elongation [GO:0060523]; prostate gland development [GO:0030850]; protein localization to nucleus [GO:0034504]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of gene expression [GO:0010468]; regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782]; regulation of odontogenesis [GO:0042481]; regulation of prostatic bud formation [GO:0060685]; regulation of protein localization to nucleus [GO:1900180]; regulation of proteolysis [GO:0030162]; regulation of transcription, DNA-templated [GO:0006355]; respiratory tube development [GO:0030323]; response to axon injury [GO:0048678]; response to ethanol [GO:0045471]; right lung development [GO:0060458]; roof of mouth development [GO:0060021]; salivary gland cavitation [GO:0060662]; signal transduction [GO:0007165]; skin development [GO:0043588]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; somite development [GO:0061053]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord motor neuron differentiation [GO:0021522]; stem cell development [GO:0048864]; striated muscle cell differentiation [GO:0051146]; striated muscle tissue development [GO:0014706]; T cell differentiation in thymus [GO:0033077]; telencephalon regionalization [GO:0021978]; thalamus development [GO:0021794]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue development [GO:0043586]; tongue morphogenesis [GO:0043587]; trachea development [GO:0060438]; trachea morphogenesis [GO:0060439]; tracheoesophageal septum formation [GO:1905327]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; ventral spinal cord interneuron specification [GO:0021521]; zona limitans intrathalamica formation [GO:0022006]	cell wall organization [GO:0071555]; response to antibiotic [GO:0046677]	anatomical structure development [GO:0048856]; anatomical structure formation involved in morphogenesis [GO:0048646]; androgen metabolic process [GO:0008209]; angiogenesis [GO:0001525]; animal organ formation [GO:0048645]; anterior/posterior pattern specification [GO:0009952]; apoptotic signaling pathway [GO:0097190]; artery development [GO:0060840]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; blood coagulation [GO:0007596]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bud outgrowth involved in lung branching [GO:0060447]; camera-type eye development [GO:0043010]; canonical Wnt signaling pathway [GO:0060070]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell-cell signaling [GO:0007267]; cell development [GO:0048468]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cell proliferation in external granule layer [GO:0021924]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; cerebellar granule cell precursor proliferation [GO:0021930]; commissural neuron axon guidance [GO:0071679]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; determination of left/right symmetry [GO:0007368]; developmental growth [GO:0048589]; digestive tract mesoderm development [GO:0007502]; digestive tract morphogenesis [GO:0048546]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic morphogenesis [GO:0048598]; embryonic organ development [GO:0048568]; embryonic skeletal system development [GO:0048706]; endocytosis [GO:0006897]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial-mesenchymal cell signaling [GO:0060684]; epithelial-mesenchymal signaling involved in prostate gland development [GO:0060738]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of cell polarity [GO:0030010]; forebrain development [GO:0030900]; forebrain regionalization [GO:0021871]; formation of anatomical boundary [GO:0048859]; fungiform papilla development [GO:0061196]; fungiform papilla formation [GO:0061198]; fungiform papilla morphogenesis [GO:0061197]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; inner ear development [GO:0048839]; intein-mediated protein splicing [GO:0016539]; intermediate filament organization [GO:0045109]; kidney development [GO:0001822]; left lung development [GO:0060459]; limb bud formation [GO:0060174]; limb development [GO:0060173]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung lobe morphogenesis [GO:0060463]; lung morphogenesis [GO:0060425]; lymphoid progenitor cell differentiation [GO:0002320]; male genitalia development [GO:0030539]; male genitalia morphogenesis [GO:0048808]; mesenchymal cell proliferation [GO:0010463]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal smoothened signaling pathway involved in prostate gland development [GO:0060783]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephros development [GO:0001656]; midbrain development [GO:0030901]; myoblast differentiation [GO:0045445]; myotube differentiation [GO:0014902]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of gene expression [GO:0010629]; negative regulation of kidney smooth muscle cell differentiation [GO:2000357]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of neuron death [GO:1901215]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of ureter smooth muscle cell differentiation [GO:2000062]; negative regulation of Wnt signaling pathway [GO:0030178]; negative thymic T cell selection [GO:0045060]; neural crest cell migration [GO:0001755]; neural tube formation [GO:0001841]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; odontogenesis [GO:0042476]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; osteoblast development [GO:0002076]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; polarity specification of anterior/posterior axis [GO:0009949]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of gene expression [GO:0010628]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of kidney smooth muscle cell differentiation [GO:2000358]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mesenchymal cell proliferation involved in ureter development [GO:2000729]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neurotrophin production [GO:0032901]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; positive regulation of penile erection [GO:0060406]; positive regulation of photoreceptor cell differentiation [GO:0046534]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sclerotome development [GO:0061189]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ureter smooth muscle cell differentiation [GO:2000063]; positive regulation of Wnt signaling pathway [GO:0030177]; positive thymic T cell selection [GO:0045059]; primary prostatic bud elongation [GO:0060516]; prostate epithelial cord elongation [GO:0060523]; prostate gland development [GO:0030850]; protein localization to nucleus [GO:0034504]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of gene expression [GO:0010468]; regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782]; regulation of odontogenesis [GO:0042481]; regulation of prostatic bud formation [GO:0060685]; regulation of protein localization to nucleus [GO:1900180]; regulation of proteolysis [GO:0030162]; regulation of transcription, DNA-templated [GO:0006355]; respiratory tube development [GO:0030323]; response to axon injury [GO:0048678]; response to ethanol [GO:0045471]; right lung development [GO:0060458]; roof of mouth development [GO:0060021]; salivary gland cavitation [GO:0060662]; signal transduction [GO:0007165]; skin development [GO:0043588]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; somite development [GO:0061053]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord motor neuron differentiation [GO:0021522]; stem cell development [GO:0048864]; striated muscle cell differentiation [GO:0051146]; striated muscle tissue development [GO:0014706]; T cell differentiation in thymus [GO:0033077]; telencephalon regionalization [GO:0021978]; thalamus development [GO:0021794]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue development [GO:0043586]; tongue morphogenesis [GO:0043587]; trachea development [GO:0060438]; trachea morphogenesis [GO:0060439]; tracheoesophageal septum formation [GO:1905327]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; ventral spinal cord interneuron specification [GO:0021521]; zona limitans intrathalamica formation [GO:0022006]		axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]; transport vesicle [GO:0030133]	dipeptidase activity [GO:0016805]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; laminin-1 binding [GO:0043237]; patched binding [GO:0005113]; zinc ion binding [GO:0008270]
d1r44e__d3n1qa___1		Metazoa	Firmicutes	Chordata	dipeptidase activity [GO:0016805]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; cell wall organization [GO:0071555]; response to antibiotic [GO:0046677]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anterior/posterior pattern specification [GO:0009952]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; cerebral cortex development [GO:0021987]; embryonic body morphogenesis [GO:0010172]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; lens development in camera-type eye [GO:0002088]; myoblast fusion [GO:0007520]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of protein binding [GO:0043393]; skeletal muscle satellite cell differentiation [GO:0014816]; smoothened signaling pathway [GO:0007224]	cell wall organization [GO:0071555]; response to antibiotic [GO:0046677]	anterior/posterior pattern specification [GO:0009952]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; cerebral cortex development [GO:0021987]; embryonic body morphogenesis [GO:0010172]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; lens development in camera-type eye [GO:0002088]; myoblast fusion [GO:0007520]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of protein binding [GO:0043393]; skeletal muscle satellite cell differentiation [GO:0014816]; smoothened signaling pathway [GO:0007224]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	dipeptidase activity [GO:0016805]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	
d1r46a2_d5u3aa1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1r46b2_d2vzvb3__1	Metazoa		Chordata	Actinobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1r47a2_d5ofla1__1	Metazoa		Chordata	Firmicutes	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	integral component of membrane [GO:0016021]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cellulose catabolic process [GO:0030245]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	integral component of membrane [GO:0016021]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d1r47b1_d1cyga3__1	Metazoa		Chordata	Firmicutes	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1r47b2_d1iswb2__1	Metazoa		Chordata	Actinobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	polysaccharide catabolic process [GO:0000272]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	endo-1,4-beta-xylanase activity [GO:0031176]
d1r4ab__d3qvva___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; trans-Golgi network [GO:0005802]; GTPase binding [GO:0051020]; Golgi to plasma membrane protein transport [GO:0043001]; positive regulation of axon extension [GO:0045773]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; aryl sulfotransferase activity [GO:0004062]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]	Golgi to plasma membrane protein transport [GO:0043001]; positive regulation of axon extension [GO:0045773]; vesicle-mediated transport [GO:0016192]	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; trans-Golgi network [GO:0005802]	cytosol [GO:0005829]	GTPase binding [GO:0051020]	aryl sulfotransferase activity [GO:0004062]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]
d1r4ba__d5kpnb2__1		Metazoa		Chordata	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	transferase activity, transferring pentosyl groups [GO:0016763]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1r4cd__d2octa___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; tertiary granule lumen [GO:1904724]; amyloid-beta binding [GO:0001540]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; identical protein binding [GO:0042802]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; cellular protein metabolic process [GO:0044267]; defense response [GO:0006952]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of collagen catabolic process [GO:0010711]; negative regulation of elastin catabolic process [GO:0060311]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]; post-translational protein modification [GO:0043687]; regulation of tissue remodeling [GO:0034103]; supramolecular fiber organization [GO:0097435]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; protease binding [GO:0002020]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]	cellular protein metabolic process [GO:0044267]; defense response [GO:0006952]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of collagen catabolic process [GO:0010711]; negative regulation of elastin catabolic process [GO:0060311]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]; post-translational protein modification [GO:0043687]; regulation of tissue remodeling [GO:0034103]; supramolecular fiber organization [GO:0097435]	adult locomotory behavior [GO:0008344]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; tertiary granule lumen [GO:1904724]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	amyloid-beta binding [GO:0001540]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; identical protein binding [GO:0042802]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; protease binding [GO:0002020]; RNA binding [GO:0003723]
d1r4la__d3fuia2__1	Metazoa	Metazoa	Chordata	Chordata	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1r4mi__d3n30b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]; cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1r4mi__d3wa0e1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]; cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d1r4mj__d5b83d4__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]; cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1r4mk__d1wgha1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]; cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	plasma membrane [GO:0005886]	cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	plasma membrane [GO:0005886]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]	
d1r4nl__d3prpd___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	ribosome [GO:0005840]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	translation [GO:0006412]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ribosome [GO:0005840]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	structural constituent of ribosome [GO:0003735]
d1r4pc__d1dm0k___1				Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; negative regulation of translation [GO:0017148]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]		toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1r4qg__d3ea6a1__1			Proteobacteria	Firmicutes	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	negative regulation of translation [GO:0017148]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]
d1r4sa1_d1r51a2__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1r4wa__d3hjpa1__1	Metazoa		Chordata	Crenarchaeota	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]
d1r4wc__d2b7kb___1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; copper ion binding [GO:0005507]; cell redox homeostasis [GO:0045454]; cellular copper ion homeostasis [GO:0006878]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]	epithelial cell differentiation [GO:0030855]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; cellular copper ion homeostasis [GO:0006878]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	cell [GO:0005623]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]	copper ion binding [GO:0005507]
d1r4ya__d1jbsa___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]; rRNA endonuclease activity [GO:0033902]; negative regulation of translation [GO:0017148]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]; negative regulation of translation [GO:0017148]	negative regulation of translation [GO:0017148]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]; rRNA endonuclease activity [GO:0033902]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1r4za__d2ocia___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; alpha-amino-acid esterase activity [GO:0047658]; cellular amino acid metabolic process [GO:0006520]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	lipid catabolic process [GO:0016042]	cellular amino acid metabolic process [GO:0006520]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	extracellular region [GO:0005576]	mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	alpha-amino-acid esterase activity [GO:0047658]
d1r4zb__d5aica2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipid catabolic process [GO:0016042]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	extracellular region [GO:0005576]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d1r50a__d4ea6a___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]		lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	triglyceride lipase activity [GO:0004806]
d1r51a1_d1gtps___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1r51a2_d5m98f2__1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1r54a__d1d5ja___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	proteolysis [GO:0006508]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	integral component of membrane [GO:0016021]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1r55a1_d5t9qa___1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	proteolysis [GO:0006508]		integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1r56a1_d4mb8b2__1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1r56b1_d2obab1__1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]; queuosine biosynthetic process [GO:0008616]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	queuosine biosynthetic process [GO:0008616]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]
d1r56b2_d1n3sb___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1r56b2_d2yzeg1__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1r56c1_d2obaf1__1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]; queuosine biosynthetic process [GO:0008616]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	queuosine biosynthetic process [GO:0008616]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]
d1r56c2_d5m98g2__1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1r56d1_d1wure___1	Fungi		Ascomycota	Deinococcus-Thermus	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1r56e1_d1a9cg___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1r56e2_d1gtqb___1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin biosynthetic process [GO:0006729]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	tetrahydrobiopterin biosynthetic process [GO:0006729]	peroxisome [GO:0005777]	mitochondrion [GO:0005739]	urate oxidase activity [GO:0004846]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d1r56h1_d1gtpl___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1r56h1_d1xy3e2__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1r57a1_d4cafb1__1			Firmicutes	Apicomplexa		glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]		N-terminal protein myristoylation [GO:0006499]				glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d1r59o2_d4czha1__1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATP binding [GO:0005524]
d1r5aa2_d2yzhd1__1	Metazoa		Arthropoda	Aquificae	metal ion binding [GO:0046872]; transferase activity [GO:0016740]	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]	thioredoxin peroxidase activity [GO:0008379]
d1r5cb__d1o0ga___1	Metazoa		Chordata		extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]		RNA phosphodiester bond hydrolysis [GO:0090501]		extracellular region [GO:0005576]		endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	
d1r5ia1_d1zhna1__1		Metazoa	Tenericutes	Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1r5ia1_d4i3sl2__1			Tenericutes			host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1r5ie1_d4hija2__1			Tenericutes									
d1r5if1_d3vi3l1__1		Metazoa	Tenericutes	Chordata		alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integrin alpha5-beta1 complex [GO:0034674]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]; epidermal growth factor receptor binding [GO:0005154]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor receptor binding [GO:0005161]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; angiogenesis [GO:0001525]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory [GO:0007613]; negative regulation of anoikis [GO:2000811]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; wound healing, spreading of epidermal cells [GO:0035313]		angiogenesis [GO:0001525]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory [GO:0007613]; negative regulation of anoikis [GO:2000811]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; wound healing, spreading of epidermal cells [GO:0035313]		alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integrin alpha5-beta1 complex [GO:0034674]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]		epidermal growth factor receptor binding [GO:0005154]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor receptor binding [GO:0005161]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]
d1r5if1_d5i66b2__1			Tenericutes									
d1r5if2_d5bxfa1__1		Metazoa	Tenericutes	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1r5oa1_d4acba2__1	Fungi		Ascomycota	Euryarchaeota	cytosol [GO:0005829]; translation release factor complex [GO:0018444]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; guanyl-nucleotide exchange factor activity [GO:0005085]; magnesium ion binding [GO:0000287]; protein C-terminus binding [GO:0008022]; translation release factor activity [GO:0003747]; cytoplasmic translational termination [GO:0002184]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; translation [GO:0006412]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; selenocysteine incorporation [GO:0001514]	cytoplasmic translational termination [GO:0002184]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; translation [GO:0006412]	selenocysteine incorporation [GO:0001514]	cytosol [GO:0005829]; translation release factor complex [GO:0018444]	cytoplasm [GO:0005737]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; guanyl-nucleotide exchange factor activity [GO:0005085]; magnesium ion binding [GO:0000287]; protein C-terminus binding [GO:0008022]; translation release factor activity [GO:0003747]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1r5ra__d1ooix___1		Metazoa		Arthropoda		extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]		courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]		dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]
d1r5tc__d4lc5b1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; cytidine catabolic process [GO:0006216]; cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; pyrimidine-containing compound salvage [GO:0008655]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]	cytidine catabolic process [GO:0006216]; cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; pyrimidine-containing compound salvage [GO:0008655]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]
d1r5va1_d3rtqb___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1r5wa1_d3u7yl1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1r5wb1_d5m94d___1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; metal ion transmembrane transporter activity [GO:0046873]; symporter activity [GO:0015293]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		metal ion binding [GO:0046872]; metal ion transmembrane transporter activity [GO:0046873]; symporter activity [GO:0015293]
d1r5wb2_d1s8da2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1r5wc1_d1um6h1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]			
d1r5wd1_d3q1sl1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]; acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]
d1r5wd2_d3rtqa1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1r64b2_d3f7oa___1	Fungi	Fungi	Ascomycota	Ascomycota	fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]		fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1r64b2_d4hx2c___1	Fungi		Ascomycota	Actinobacteria	fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]	serine-type endopeptidase inhibitor activity [GO:0004867]	peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]		fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1r65b__d1oqua___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ribonucleoside-diphosphate reductase complex [GO:0005971]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1r6aa__d5k0lb___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d1r6bx1_d1qvra1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; ATP binding [GO:0005524]; ATP-dependent peptidase activity [GO:0004176]; ATPase activity [GO:0016887]; protein unfolding [GO:0043335]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein metabolic process [GO:0019538]; protein refolding [GO:0042026]; response to heat [GO:0009408]	protein unfolding [GO:0043335]; response to oxidative stress [GO:0006979]	protein metabolic process [GO:0019538]; protein refolding [GO:0042026]; response to heat [GO:0009408]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; ATP-dependent peptidase activity [GO:0004176]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]
d1r6ja1_d3shub1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]; actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell projection [GO:0042995]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of cell migration [GO:0030335]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]	cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]	cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]
d1r6ma2_d2c38w2__1			Proteobacteria	Crenarchaeota	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	3'-5'-exoribonuclease activity [GO:0000175]
d1r6wa1_d2ggeb1__1			Proteobacteria	Firmicutes	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	menaquinone biosynthetic process [GO:0009234]				hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d1r6xa2_d1i2db2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1r6za2_d4powa___1	Metazoa		Arthropoda	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; messenger ribonucleoprotein complex [GO:1990124]; neuronal ribonucleoprotein granule [GO:0071598]; nucleus [GO:0005634]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]; endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; siRNA binding [GO:0035197]; cellular response to virus [GO:0098586]; cellularization [GO:0007349]; defense response to virus [GO:0051607]; dosage compensation by hyperactivation of X chromosome [GO:0009047]; dsRNA transport [GO:0033227]; gene silencing by miRNA [GO:0035195]; heterochromatin organization involved in chromatin silencing [GO:0070868]; negative regulation of transposition, RNA-mediated [GO:0010526]; negative regulation of viral genome replication [GO:0045071]; pole cell formation [GO:0007279]; production of siRNA involved in RNA interference [GO:0030422]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; syncytial nuclear migration [GO:0035190]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; viral process [GO:0016032]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	cellularization [GO:0007349]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; dosage compensation by hyperactivation of X chromosome [GO:0009047]; dsRNA transport [GO:0033227]; gene silencing by miRNA [GO:0035195]; heterochromatin organization involved in chromatin silencing [GO:0070868]; negative regulation of transposition, RNA-mediated [GO:0010526]; negative regulation of viral genome replication [GO:0045071]; pole cell formation [GO:0007279]; production of siRNA involved in RNA interference [GO:0030422]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; syncytial nuclear migration [GO:0035190]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; viral process [GO:0016032]	nitrogen compound transport [GO:0071705]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; messenger ribonucleoprotein complex [GO:1990124]; neuronal ribonucleoprotein granule [GO:0071598]; nucleus [GO:0005634]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; siRNA binding [GO:0035197]	ligand-gated ion channel activity [GO:0015276]
d1r6zp2_d5ehmb___1	Metazoa	Metazoa	Arthropoda	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; messenger ribonucleoprotein complex [GO:1990124]; neuronal ribonucleoprotein granule [GO:0071598]; nucleus [GO:0005634]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]; endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; siRNA binding [GO:0035197]; cellular response to virus [GO:0098586]; cellularization [GO:0007349]; defense response to virus [GO:0051607]; dosage compensation by hyperactivation of X chromosome [GO:0009047]; dsRNA transport [GO:0033227]; gene silencing by miRNA [GO:0035195]; heterochromatin organization involved in chromatin silencing [GO:0070868]; negative regulation of transposition, RNA-mediated [GO:0010526]; negative regulation of viral genome replication [GO:0045071]; pole cell formation [GO:0007279]; production of siRNA involved in RNA interference [GO:0030422]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; syncytial nuclear migration [GO:0035190]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; viral process [GO:0016032]	cell [GO:0005623]; cell junction [GO:0030054]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic active zone [GO:0048786]; glutamate receptor activity [GO:0008066]; glutamate-gated calcium ion channel activity [GO:0022849]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; calcium ion import across plasma membrane [GO:0098703]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of neuromuscular synaptic transmission [GO:1900075]; regulation of synaptic activity [GO:0060025]; synaptic transmission, glutamatergic [GO:0035249]	cellularization [GO:0007349]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; dosage compensation by hyperactivation of X chromosome [GO:0009047]; dsRNA transport [GO:0033227]; gene silencing by miRNA [GO:0035195]; heterochromatin organization involved in chromatin silencing [GO:0070868]; negative regulation of transposition, RNA-mediated [GO:0010526]; negative regulation of viral genome replication [GO:0045071]; pole cell formation [GO:0007279]; production of siRNA involved in RNA interference [GO:0030422]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; syncytial nuclear migration [GO:0035190]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; viral process [GO:0016032]	calcium ion import across plasma membrane [GO:0098703]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of neuromuscular synaptic transmission [GO:1900075]; regulation of synaptic activity [GO:0060025]; synaptic transmission, glutamatergic [GO:0035249]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; messenger ribonucleoprotein complex [GO:1990124]; neuronal ribonucleoprotein granule [GO:0071598]; nucleus [GO:0005634]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]	cell [GO:0005623]; cell junction [GO:0030054]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic active zone [GO:0048786]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; siRNA binding [GO:0035197]	glutamate-gated calcium ion channel activity [GO:0022849]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1r6zz2_d1a99b___1	Metazoa		Arthropoda	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; messenger ribonucleoprotein complex [GO:1990124]; neuronal ribonucleoprotein granule [GO:0071598]; nucleus [GO:0005634]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]; endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; siRNA binding [GO:0035197]; cellular response to virus [GO:0098586]; cellularization [GO:0007349]; defense response to virus [GO:0051607]; dosage compensation by hyperactivation of X chromosome [GO:0009047]; dsRNA transport [GO:0033227]; gene silencing by miRNA [GO:0035195]; heterochromatin organization involved in chromatin silencing [GO:0070868]; negative regulation of transposition, RNA-mediated [GO:0010526]; negative regulation of viral genome replication [GO:0045071]; pole cell formation [GO:0007279]; production of siRNA involved in RNA interference [GO:0030422]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; syncytial nuclear migration [GO:0035190]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; viral process [GO:0016032]	outer membrane-bounded periplasmic space [GO:0030288]; putrescine binding [GO:0019810]; putrescine transport [GO:0015847]	cellularization [GO:0007349]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; dosage compensation by hyperactivation of X chromosome [GO:0009047]; dsRNA transport [GO:0033227]; gene silencing by miRNA [GO:0035195]; heterochromatin organization involved in chromatin silencing [GO:0070868]; negative regulation of transposition, RNA-mediated [GO:0010526]; negative regulation of viral genome replication [GO:0045071]; pole cell formation [GO:0007279]; production of siRNA involved in RNA interference [GO:0030422]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; syncytial nuclear migration [GO:0035190]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; viral process [GO:0016032]	putrescine transport [GO:0015847]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; messenger ribonucleoprotein complex [GO:1990124]; neuronal ribonucleoprotein granule [GO:0071598]; nucleus [GO:0005634]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]	outer membrane-bounded periplasmic space [GO:0030288]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; siRNA binding [GO:0035197]	putrescine binding [GO:0019810]
d1r6zz2_d3r39a1__1	Metazoa		Arthropoda		cytoplasm [GO:0005737]; cytosol [GO:0005829]; messenger ribonucleoprotein complex [GO:1990124]; neuronal ribonucleoprotein granule [GO:0071598]; nucleus [GO:0005634]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]; endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; siRNA binding [GO:0035197]; cellular response to virus [GO:0098586]; cellularization [GO:0007349]; defense response to virus [GO:0051607]; dosage compensation by hyperactivation of X chromosome [GO:0009047]; dsRNA transport [GO:0033227]; gene silencing by miRNA [GO:0035195]; heterochromatin organization involved in chromatin silencing [GO:0070868]; negative regulation of transposition, RNA-mediated [GO:0010526]; negative regulation of viral genome replication [GO:0045071]; pole cell formation [GO:0007279]; production of siRNA involved in RNA interference [GO:0030422]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; syncytial nuclear migration [GO:0035190]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; viral process [GO:0016032]		cellularization [GO:0007349]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; dosage compensation by hyperactivation of X chromosome [GO:0009047]; dsRNA transport [GO:0033227]; gene silencing by miRNA [GO:0035195]; heterochromatin organization involved in chromatin silencing [GO:0070868]; negative regulation of transposition, RNA-mediated [GO:0010526]; negative regulation of viral genome replication [GO:0045071]; pole cell formation [GO:0007279]; production of siRNA involved in RNA interference [GO:0030422]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; syncytial nuclear migration [GO:0035190]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; messenger ribonucleoprotein complex [GO:1990124]; neuronal ribonucleoprotein granule [GO:0071598]; nucleus [GO:0005634]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]		endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; siRNA binding [GO:0035197]	
d1r72a4_d3ikvb2__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]		negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]		cytoplasm [GO:0005737]		coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1r72d3_d3keob1__1				Firmicutes		cytoplasm [GO:0005737]; coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]		negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]		cytoplasm [GO:0005737]		coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1r72f4_d3hadb2__1		Metazoa		Chordata		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]		3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d1r7ma2_d1dfaa3__1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrion [GO:0005739]; endonuclease activity [GO:0004519]; intron homing [GO:0006314]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	intron homing [GO:0006314]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	mitochondrion [GO:0005739]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	endonuclease activity [GO:0004519]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]
d1r7ra4_d4kodi2__1	Metazoa	Metazoa	Chordata	Chordata	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1r7sc__d1xlob___1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1r85a__d1eoka___1			Firmicutes	Bacteroidetes	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]
d1r88a__d1qfsa2__1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; fibronectin binding [GO:0001968]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; zymogen binding [GO:0035375]; mycolate cell wall layer assembly [GO:0071769]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	mycolate cell wall layer assembly [GO:0071769]		extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	fibronectin binding [GO:0001968]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; zymogen binding [GO:0035375]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d1r89a1_d2o1pb1__1		Fungi	Euryarchaeota	Ascomycota	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]		mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d1r8aa1_d4lt6a2__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]		cytosol [GO:0005829]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d1r8ba1_d3c66a1__1		Fungi	Euryarchaeota	Ascomycota	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]		mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d1r8na__d2nyya4__1	Viridiplantae		Streptophyta	Firmicutes	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	serine-type endopeptidase inhibitor activity [GO:0004867]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1r8qe__d4jmoa1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; inositol 1,4,5 trisphosphate binding [GO:0070679]; lipid binding [GO:0008289]; actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; regulation of ARF protein signal transduction [GO:0032012]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; inositol 1,4,5 trisphosphate binding [GO:0070679]; lipid binding [GO:0008289]; actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; regulation of ARF protein signal transduction [GO:0032012]	actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; regulation of ARF protein signal transduction [GO:0032012]	actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; regulation of ARF protein signal transduction [GO:0032012]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; membrane [GO:0016020]; plasma membrane [GO:0005886]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; inositol 1,4,5 trisphosphate binding [GO:0070679]; lipid binding [GO:0008289]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; inositol 1,4,5 trisphosphate binding [GO:0070679]; lipid binding [GO:0008289]
d1r9db__d5a0uc___1			Firmicutes	Proteobacteria	catalytic activity [GO:0003824]	carbon-nitrogen lyase activity [GO:0016840]; choline catabolic process [GO:0042426]		choline catabolic process [GO:0042426]			catalytic activity [GO:0003824]	carbon-nitrogen lyase activity [GO:0016840]
d1r9eb__d5cnsd2__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1r9ja3_d2g28a3__1				Proteobacteria	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytosol [GO:0005829]; membrane [GO:0016020]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]
d1r9jb1_d2ez9a2__1				Firmicutes	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]					metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d1r9jb1_d2g25b1__1				Proteobacteria	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytosol [GO:0005829]; membrane [GO:0016020]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]
d1r9jb2_d2wvge1__1				Proteobacteria	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]					metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1r9nd2_d1xfdc2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]; potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]
d1r9nd2_d4inza___1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	pyrimidine-5'-nucleotide nucleosidase activity [GO:0047405]; metabolic process [GO:0008152]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	metabolic process [GO:0008152]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	pyrimidine-5'-nucleotide nucleosidase activity [GO:0047405]
d1ra2a__d3eekb1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d1ra2a__d3lg4b___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d1ra8a__d2w9sb___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d1ra9a__d3fqva___1			Proteobacteria		cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	
d1ra9a__d3s7aa___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1raaa2_d4anfc2__1			Proteobacteria	Tenericutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1raba1_d3e2pf2__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1raca1_d4e2fa2__1			Proteobacteria	Proteobacteria	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]; zinc ion binding [GO:0008270]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1rada2_d2i6ua1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1raec1_d3m4na2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]
d1rafa1_d3e2pi2__1			Proteobacteria	Euryarchaeota	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]; zinc ion binding [GO:0008270]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1rafa2_d1nbec1__1			Proteobacteria	Proteobacteria	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]; zinc ion binding [GO:0008270]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1raga1_d2w37a2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine catabolic process to ornithine [GO:0019547]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]
d1raga2_d2p2ge1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1ragc2_d4h31c1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1rahb1_d2at1b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1rahc1_d3r7le2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1rama2_d1pzud2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1ramb2_d1ljma___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; chondrocyte differentiation [GO:0002062]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; peripheral nervous system neuron development [GO:0048935]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytokine-mediated signaling pathway [GO:0001959]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of keratinocyte differentiation [GO:0045616]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of myeloid cell differentiation [GO:0045637]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of Wnt signaling pathway [GO:0030111]	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	chondrocyte differentiation [GO:0002062]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; peripheral nervous system neuron development [GO:0048935]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytokine-mediated signaling pathway [GO:0001959]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of keratinocyte differentiation [GO:0045616]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of myeloid cell differentiation [GO:0045637]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of Wnt signaling pathway [GO:0030111]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]	core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1rb0a__d3ilja___1			Proteobacteria	Proteobacteria	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]			2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]
d1rb3b__d5uipb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d1rb7a__d2z3hb___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d1rbbb__d2i5sx___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]		endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]
d1rbc.1_d2p45a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1rblb2_d2oekb1__1			Cyanobacteria	Firmicutes	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity [GO:0043715]; magnesium ion binding [GO:0000287]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]	reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]			monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity [GO:0043715]; magnesium ion binding [GO:0000287]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rblc2_d1rsca2__1			Cyanobacteria	Cyanobacteria	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]			monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rblh2_d3kdna1__1			Cyanobacteria	Euryarchaeota	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	reductive pentose-phosphate cycle [GO:0019253]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]			monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rblk__d4f0mb___1			Cyanobacteria	Rhodophyta	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rboh2_d1bxne2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]		magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rbqc__d5j63b1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	coenzyme binding [GO:0050662]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; response to antibiotic [GO:0046677]	'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	coenzyme binding [GO:0050662]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]
d1rbva__d1hysa1__1			Proteobacteria		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1rbwa__d2xoia___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1rbzb__d1cdda___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]	'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d1rc4a__d3jvxa1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1rc4a__d3ntza___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1rc5b1_d1ztda1__1			Aquificae	Euryarchaeota	cytoplasm [GO:0005737]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]; mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	ribonuclease III activity [GO:0004525]; RNA processing [GO:0006396]	mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	RNA processing [GO:0006396]	cytoplasm [GO:0005737]		double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]	ribonuclease III activity [GO:0004525]
d1rc9a1_d3mz8a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1rcda__d2x179___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]
d1rcea__d1mmoc___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1rcfa__d3o2na___1		Metazoa	Cyanobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1rcfa__d5fx2a___1			Cyanobacteria	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1rcha__d1wsfa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1rcha__d5vqua2__1			Proteobacteria		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1rcia__d4toat___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1rcka__d3hohb___1	Fungi	Fungi	Ascomycota	Ascomycota	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]				cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1rcob2_d5hanl1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]		magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rcoh1_d2d69d1__1	Viridiplantae		Streptophyta	Euryarchaeota	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]		magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rcoh2_d5hjyb1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]		magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rcol2_d4hhhd1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rcop__d1ir2l___1	Viridiplantae	Viridiplantae	Streptophyta	Chlorophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rcot__d1ir2i___1	Viridiplantae	Viridiplantae	Streptophyta	Chlorophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rcov2_d1wdde2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rcpb__d5l32a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1rcvh__d1eu4a1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1rcxb1_d1rlcl1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rcxf__d3axmv___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rcxs__d2v68o___1	Viridiplantae	Viridiplantae	Streptophyta	Chlorophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rcxt__d2v69o___1	Viridiplantae	Viridiplantae	Streptophyta	Chlorophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rcya__d1wa2x2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1rd3.2_d1lvoa___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1rd4c__d3ppva1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d1rd5a__d4fire___1	Viridiplantae		Streptophyta	Euryarchaeota	chloroplast [GO:0009507]; indole-3-glycerol-phosphate lyase activity [GO:0033984]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; pyridoxal phosphate biosynthetic process [GO:0042823]	tryptophan biosynthetic process [GO:0000162]	pyridoxal phosphate biosynthetic process [GO:0042823]	chloroplast [GO:0009507]		indole-3-glycerol-phosphate lyase activity [GO:0033984]; tryptophan synthase activity [GO:0004834]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d1rd6a1_d2jhub2__1		Metazoa	Proteobacteria	Chordata	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]
d1rd7a__d1d1gb___1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d1rd7a__d2w9sf___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d1rd7b__d4g3mc2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d1rd8a1_d4mhic1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rd9h__d1dm0i___1			Proteobacteria	Proteobacteria	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; negative regulation of translation [GO:0017148]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	negative regulation of translation [GO:0017148]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]		galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1rdaa__d1lawa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1rdca__d1wsea1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1rdda__d2qk9a1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA catabolic process [GO:0006401]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA catabolic process [GO:0006401]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1rdda__d3aa5x___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1rdfd__d2autd___1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	organic phosphonate catabolic process [GO:0019700]			outer membrane-bounded periplasmic space [GO:0030288]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]
d1rdk1__d2i83a___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; collagen binding [GO:0005518]; hyaluronic acid binding [GO:0005540]; transmembrane signaling receptor activity [GO:0004888]; cartilage development [GO:0051216]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cellular response to fibroblast growth factor stimulus [GO:0044344]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte migration [GO:0050900]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; wound healing, spreading of cells [GO:0044319]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	cartilage development [GO:0051216]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte migration [GO:0050900]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; wound healing, spreading of cells [GO:0044319]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]	collagen binding [GO:0005518]; hyaluronic acid binding [GO:0005540]; transmembrane signaling receptor activity [GO:0004888]
d1rdl1__d2q17a___1	Metazoa		Chordata	Actinobacteria	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	endoplasmic reticulum [GO:0005783]; calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]; post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	endoplasmic reticulum [GO:0005783]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]	calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]
d1rdn1__d4n35d___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1rdn2__d1ypoh___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d1rdph__d1ct1h___1			Proteobacteria	Proteobacteria	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d1rdwx2_d5br9b1__1	Metazoa		Chordata	Proteobacteria	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	
d1re4e1_d2j0gb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1re7b__d3n0ha___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1re7b__d5ecxa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1re9a__d3na1b___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	(+)-camphor catabolic process [GO:0019383]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]
d1reda1_d1ks4a___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulase activity [GO:0008810]; transferase activity [GO:0016740]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	cellulase activity [GO:0008810]; transferase activity [GO:0016740]
d1reea1_d2area___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1reea1_d2nlra___1	Fungi		Ascomycota	Actinobacteria	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]
d1refb1_d1h4hd___1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d1refb1_d2dtyb___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]
d1reoa2_d1pdha2__1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179]	benzoate catabolic process via hydroxylation [GO:0043640]	extracellular region [GO:0005576]		L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1reqb1_d2reqa1__1			Actinobacteria	Actinobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]					cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d1reqb2_d1i9cc___1			Actinobacteria	Firmicutes	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]; anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]		anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]			cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]
d1reqc1_d1mmfa___1			Actinobacteria	Proteobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; glycerol dehydratase activity [GO:0046405]					cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; glycerol dehydratase activity [GO:0046405]
d1reqc2_d1ccwa___1			Actinobacteria	Firmicutes	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]; anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]		anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]			cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]
d1rera1_d2d7oa1__1		Metazoa		Chordata	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]
d1rerb1_d5wszc___1				Firmicutes	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d1rerc1_d1i75a1__1				Firmicutes	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1reya__d1ouba___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1reza__d1l01a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1rf0c1_d2jhlf___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]; cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]
d1rf1c1_d2j60c___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1rf1e1_d1m1jb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	fibrinogen complex [GO:0005577]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor binding [GO:0005102]
d1rf1f1_d2j60a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1rf2d__d1ltsh___1			Proteobacteria	Proteobacteria	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1rf2e__d1bose___1			Proteobacteria		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1rf2e__d2xnac1__1		Metazoa	Proteobacteria	Chordata	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1rf2h__d1fnwc1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1rf6b__d4r7ua___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; 3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity [GO:0008760]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylgalactosamine biosynthetic process [GO:0019277]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylgalactosamine biosynthetic process [GO:0019277]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity [GO:0008760]
d1rf7a__d3qlza1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d1rf8a__d4ueca1__1	Fungi	Metazoa	Ascomycota	Arthropoda	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; eukaryotic translation initiation factor 4F complex [GO:0016281]; mitochondrion [GO:0005739]; P-body [GO:0000932]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743]; positive regulation of cell death [GO:0010942]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; regulation of cellular protein metabolic process [GO:0032268]; ribosomal large subunit biogenesis [GO:0042273]; stress granule assembly [GO:0034063]; translational initiation [GO:0006413]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; messenger ribonucleoprotein complex [GO:1990124]; mRNA cap binding complex [GO:0005845]; muscle cell postsynaptic specialization [GO:0097482]; neuromuscular junction [GO:0031594]; neuronal ribonucleoprotein granule [GO:0071598]; P-body [GO:0000932]; postsynapse [GO:0098794]; eukaryotic initiation factor 4G binding [GO:0031370]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA cap binding [GO:0000339]; translation initiation factor activity [GO:0003743]; translation regulator activity [GO:0045182]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; RNA metabolic process [GO:0016070]; translation [GO:0006412]; translational initiation [GO:0006413]	positive regulation of cell death [GO:0010942]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; regulation of cellular protein metabolic process [GO:0032268]; ribosomal large subunit biogenesis [GO:0042273]; stress granule assembly [GO:0034063]; translational initiation [GO:0006413]	regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; RNA metabolic process [GO:0016070]; translation [GO:0006412]; translational initiation [GO:0006413]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; eukaryotic translation initiation factor 4F complex [GO:0016281]; mitochondrion [GO:0005739]; P-body [GO:0000932]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; messenger ribonucleoprotein complex [GO:1990124]; mRNA cap binding complex [GO:0005845]; muscle cell postsynaptic specialization [GO:0097482]; neuromuscular junction [GO:0031594]; neuronal ribonucleoprotein granule [GO:0071598]; P-body [GO:0000932]; postsynapse [GO:0098794]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]; translation initiation factor activity [GO:0003743]	eukaryotic initiation factor 4G binding [GO:0031370]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA cap binding [GO:0000339]; translation initiation factor activity [GO:0003743]; translation regulator activity [GO:0045182]
d1rfdh1_d5hy9a2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1rfja__d2pasa___1	Viridiplantae	Metazoa	Streptophyta	Chordata	calcium ion binding [GO:0005509]; calcium-mediated signaling [GO:0019722]	calcium ion binding [GO:0005509]	calcium-mediated signaling [GO:0019722]				calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]
d1rfkb__d2cjoa___1			Cyanobacteria	Cyanobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1rfpa__d128la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1rfqa2_d2qu4a1__1	Metazoa		Chordata	Proteobacteria	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	identical protein binding [GO:0042802]; plasmid partitioning [GO:0030541]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	plasmid partitioning [GO:0030541]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	identical protein binding [GO:0042802]
d1rfsa__d1g8jd___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane [GO:0009535]; integral component of membrane [GO:0016021]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity [GO:0045158]; metal ion binding [GO:0046872]; plastoquinol--plastocyanin reductase activity [GO:0009496]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]			chloroplast thylakoid membrane [GO:0009535]; integral component of membrane [GO:0016021]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity [GO:0045158]; metal ion binding [GO:0046872]; plastoquinol--plastocyanin reductase activity [GO:0009496]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]
d1rfsa__d3gcfm1__1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast thylakoid membrane [GO:0009535]; integral component of membrane [GO:0016021]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity [GO:0045158]; metal ion binding [GO:0046872]; plastoquinol--plastocyanin reductase activity [GO:0009496]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]			chloroplast thylakoid membrane [GO:0009535]; integral component of membrane [GO:0016021]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity [GO:0045158]; metal ion binding [GO:0046872]; plastoquinol--plastocyanin reductase activity [GO:0009496]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1rfvb__d1rkaa___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]; pyridoxal 5'-phosphate salvage [GO:0009443]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]	pyridoxal 5'-phosphate salvage [GO:0009443]	D-ribose catabolic process [GO:0019303]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d1rfwa2_d2gpcb2__1						metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]						metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1rfwb1_d1gn4b1__1				Actinobacteria		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1rfwb1_d3esfa1__1						metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]						metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1rg0b1_d3soka___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; pilus [GO:0009289]; glycosphingolipid binding [GO:0043208]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	pilus [GO:0009289]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]	periplasmic space [GO:0042597]; pilus [GO:0009289]	pilus [GO:0009289]	glycosphingolipid binding [GO:0043208]	
d1rg1a1_d1xdpb3__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 3'-tyrosyl-DNA phosphodiesterase activity [GO:0017005]; double-stranded DNA binding [GO:0003690]; exonuclease activity [GO:0004527]; single-stranded DNA binding [GO:0003697]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012]	cytosol [GO:0005829]; periplasmic side of cell outer membrane [GO:0031241]; plasma membrane [GO:0005886]; polyphosphate kinase complex [GO:0009358]; ATP binding [GO:0005524]; diphosphotransferase activity [GO:0016778]; metal ion binding [GO:0046872]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; polyphosphate kinase activity [GO:0008976]; polyphosphate:AMP phosphotransferase activity [GO:0043751]; ATP generation from ADP [GO:0006757]; polyphosphate biosynthetic process [GO:0006799]; protein autophosphorylation [GO:0046777]	DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012]	ATP generation from ADP [GO:0006757]; polyphosphate biosynthetic process [GO:0006799]; protein autophosphorylation [GO:0046777]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; periplasmic side of cell outer membrane [GO:0031241]; plasma membrane [GO:0005886]; polyphosphate kinase complex [GO:0009358]	3'-tyrosyl-DNA phosphodiesterase activity [GO:0017005]; double-stranded DNA binding [GO:0003690]; exonuclease activity [GO:0004527]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; diphosphotransferase activity [GO:0016778]; metal ion binding [GO:0046872]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; polyphosphate:AMP phosphotransferase activity [GO:0043751]; polyphosphate kinase activity [GO:0008976]
d1rg1b1_d1xdoa3__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 3'-tyrosyl-DNA phosphodiesterase activity [GO:0017005]; double-stranded DNA binding [GO:0003690]; exonuclease activity [GO:0004527]; single-stranded DNA binding [GO:0003697]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012]	cytosol [GO:0005829]; periplasmic side of cell outer membrane [GO:0031241]; plasma membrane [GO:0005886]; polyphosphate kinase complex [GO:0009358]; ATP binding [GO:0005524]; diphosphotransferase activity [GO:0016778]; metal ion binding [GO:0046872]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; polyphosphate kinase activity [GO:0008976]; polyphosphate:AMP phosphotransferase activity [GO:0043751]; ATP generation from ADP [GO:0006757]; polyphosphate biosynthetic process [GO:0006799]; protein autophosphorylation [GO:0046777]	DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012]	ATP generation from ADP [GO:0006757]; polyphosphate biosynthetic process [GO:0006799]; protein autophosphorylation [GO:0046777]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; periplasmic side of cell outer membrane [GO:0031241]; plasma membrane [GO:0005886]; polyphosphate kinase complex [GO:0009358]	3'-tyrosyl-DNA phosphodiesterase activity [GO:0017005]; double-stranded DNA binding [GO:0003690]; exonuclease activity [GO:0004527]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; diphosphotransferase activity [GO:0016778]; metal ion binding [GO:0046872]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; polyphosphate:AMP phosphotransferase activity [GO:0043751]; polyphosphate kinase activity [GO:0008976]
d1rg8a1_d2vxti___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d1rg9a1_d4ndnb1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d1rg9a3_d3s82a2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]
d1rg9b2_d4ndna3__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d1rg9b3_d3imla2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]
d1rg9c1_d1rg9d2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d1rg9d2_d5ughd1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d1rg9d3_d2hj2a3__1			Proteobacteria		cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]		one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]		cytosol [GO:0005829]		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	
d1rgaa__d3wr2d___1	Fungi	Fungi	Ascomycota	Basidiomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]		endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1rgca__d1rn1b___1	Fungi	Fungi	Ascomycota	Ascomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1rgeb__d1b21c___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1rgfa__d1ch0b___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1rgga__d1rmsa___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1rggb__d1ttob___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1rgha__d4rnta___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1rgig1_d1jhwa2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]
d1rgig2_d3fg6h3__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]
d1rgsa1_d5kjxa___1	Metazoa	Metazoa	Chordata	Chordata	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	cAMP-dependent protein kinase complex [GO:0005952]; ciliary base [GO:0097546]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; cAMP-dependent protein kinase regulator activity [GO:0008603]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase A activity [GO:0034199]; blood coagulation [GO:0007596]; cardiac muscle cell proliferation [GO:0060038]; cellular response to glucagon stimulus [GO:0071377]; cGMP-mediated signaling [GO:0019934]; female meiotic nuclear division [GO:0007143]; intracellular signal transduction [GO:0035556]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of meiotic nuclear division [GO:0045835]; regulation of transcription by RNA polymerase II [GO:0006357]; renal water homeostasis [GO:0003091]; sarcomere organization [GO:0045214]	cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	activation of protein kinase A activity [GO:0034199]; blood coagulation [GO:0007596]; cardiac muscle cell proliferation [GO:0060038]; cellular response to glucagon stimulus [GO:0071377]; cGMP-mediated signaling [GO:0019934]; female meiotic nuclear division [GO:0007143]; intracellular signal transduction [GO:0035556]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of meiotic nuclear division [GO:0045835]; regulation of transcription by RNA polymerase II [GO:0006357]; renal water homeostasis [GO:0003091]; sarcomere organization [GO:0045214]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]	cAMP-dependent protein kinase complex [GO:0005952]; ciliary base [GO:0097546]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; cAMP-dependent protein kinase regulator activity [GO:0008603]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]
d1rh0b1_d1xdpa4__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 3'-tyrosyl-DNA phosphodiesterase activity [GO:0017005]; double-stranded DNA binding [GO:0003690]; exonuclease activity [GO:0004527]; single-stranded DNA binding [GO:0003697]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012]	cytosol [GO:0005829]; periplasmic side of cell outer membrane [GO:0031241]; plasma membrane [GO:0005886]; polyphosphate kinase complex [GO:0009358]; ATP binding [GO:0005524]; diphosphotransferase activity [GO:0016778]; metal ion binding [GO:0046872]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; polyphosphate kinase activity [GO:0008976]; polyphosphate:AMP phosphotransferase activity [GO:0043751]; ATP generation from ADP [GO:0006757]; polyphosphate biosynthetic process [GO:0006799]; protein autophosphorylation [GO:0046777]	DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012]	ATP generation from ADP [GO:0006757]; polyphosphate biosynthetic process [GO:0006799]; protein autophosphorylation [GO:0046777]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; periplasmic side of cell outer membrane [GO:0031241]; plasma membrane [GO:0005886]; polyphosphate kinase complex [GO:0009358]	3'-tyrosyl-DNA phosphodiesterase activity [GO:0017005]; double-stranded DNA binding [GO:0003690]; exonuclease activity [GO:0004527]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; diphosphotransferase activity [GO:0016778]; metal ion binding [GO:0046872]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; polyphosphate:AMP phosphotransferase activity [GO:0043751]; polyphosphate kinase activity [GO:0008976]
d1rh8a__d5lowi___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; cone cell pedicle [GO:0044316]; cytoskeleton of presynaptic active zone [GO:0048788]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; Golgi-associated vesicle [GO:0005798]; growth cone [GO:0030426]; inhibitory synapse [GO:0060077]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; parallel fiber to Purkinje cell synapse [GO:0098688]; perinuclear region of cytoplasm [GO:0048471]; presynaptic active zone [GO:0048786]; presynaptic active zone cytoplasmic component [GO:0098831]; ribbon synapse [GO:0097470]; rod spherule [GO:0044317]; synapse [GO:0045202]; terminal bouton [GO:0043195]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; profilin binding [GO:0005522]; transcription corepressor binding [GO:0001222]; cytoskeleton organization [GO:0007010]; presynaptic active zone assembly [GO:1904071]; regulation of ubiquitin protein ligase activity [GO:1904666]; synapse organization [GO:0050808]; synaptic vesicle targeting [GO:0016080]	actin cytoskeleton [GO:0015629]; anchored component of presynaptic membrane [GO:0099026]; axon [GO:0030424]; axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; intracellular organelle [GO:0043229]; lamellipodium [GO:0030027]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; SNARE complex [GO:0031201]; synaptobrevin 2-SNAP-25-syntaxin-1a complex [GO:0070044]; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex [GO:0070032]; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex [GO:0070033]; terminal bouton [GO:0043195]; voltage-gated potassium channel complex [GO:0008076]; calcium-dependent protein binding [GO:0048306]; ion channel binding [GO:0044325]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; voltage-gated potassium channel activity [GO:0005249]; axonogenesis [GO:0007409]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; endosomal transport [GO:0016197]; exocytosis [GO:0006887]; growth hormone secretion [GO:0030252]; long-term memory [GO:0007616]; neuron differentiation [GO:0030182]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin secretion [GO:0032024]; regulation of neuron projection development [GO:0010975]; regulation of synapse assembly [GO:0051963]; sleep [GO:0030431]; SNARE complex assembly [GO:0035493]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; vesicle fusion [GO:0006906]	cytoskeleton organization [GO:0007010]; presynaptic active zone assembly [GO:1904071]; regulation of ubiquitin protein ligase activity [GO:1904666]; synapse organization [GO:0050808]; synaptic vesicle targeting [GO:0016080]	axonogenesis [GO:0007409]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; endosomal transport [GO:0016197]; exocytosis [GO:0006887]; growth hormone secretion [GO:0030252]; long-term memory [GO:0007616]; neuron differentiation [GO:0030182]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin secretion [GO:0032024]; regulation of neuron projection development [GO:0010975]; regulation of synapse assembly [GO:0051963]; sleep [GO:0030431]; SNARE complex assembly [GO:0035493]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; vesicle fusion [GO:0006906]	axon [GO:0030424]; cell junction [GO:0030054]; cone cell pedicle [GO:0044316]; cytoskeleton of presynaptic active zone [GO:0048788]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; Golgi-associated vesicle [GO:0005798]; growth cone [GO:0030426]; inhibitory synapse [GO:0060077]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; parallel fiber to Purkinje cell synapse [GO:0098688]; perinuclear region of cytoplasm [GO:0048471]; presynaptic active zone [GO:0048786]; presynaptic active zone cytoplasmic component [GO:0098831]; ribbon synapse [GO:0097470]; rod spherule [GO:0044317]; synapse [GO:0045202]; terminal bouton [GO:0043195]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133]	actin cytoskeleton [GO:0015629]; anchored component of presynaptic membrane [GO:0099026]; axon [GO:0030424]; axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; intracellular organelle [GO:0043229]; lamellipodium [GO:0030027]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; SNARE complex [GO:0031201]; synaptobrevin 2-SNAP-25-syntaxin-1a complex [GO:0070044]; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex [GO:0070032]; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex [GO:0070033]; terminal bouton [GO:0043195]; voltage-gated potassium channel complex [GO:0008076]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; profilin binding [GO:0005522]; transcription corepressor binding [GO:0001222]	calcium-dependent protein binding [GO:0048306]; ion channel binding [GO:0044325]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin binding [GO:0019905]; voltage-gated potassium channel activity [GO:0005249]
d1rh9a1_d3f4va___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d1rh9a1_d5l9cb___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	extracellular region [GO:0005576]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		mannan endo-1,4-beta-mannosidase activity [GO:0016985]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1rhba__d1j80.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1rhca__d1f07c___1			Euryarchaeota	Euryarchaeota	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity [GO:0018537]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]		methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]		cytoplasm [GO:0005737]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity [GO:0018537]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1rhha2_d3he7c1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1rhhb2_d1uz6p1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1rhhc2_d1kelh1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1rhhd1_d3hkfa2__1												
d1rhi1__d2c8ic1__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1rhi1__d3zfeb___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1rhi.1_d4y5zp___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1rhi.1_d5nem3___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell junction [GO:0030054]; centrosome [GO:0005813]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alphav-beta6 complex [GO:0034685]; integrin complex [GO:0008305]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; regulation of transforming growth factor beta activation [GO:1901388]; transforming growth factor-beta secretion [GO:0038044]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; regulation of transforming growth factor beta activation [GO:1901388]; transforming growth factor-beta secretion [GO:0038044]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cell junction [GO:0030054]; centrosome [GO:0005813]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alphav-beta6 complex [GO:0034685]; integrin complex [GO:0008305]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]
d1rhi3__d1po21___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1rhla__d5hohd___1	Fungi	Fungi	Ascomycota	Ascomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1rhr.1_d1pyo.1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; aspartic-type endopeptidase activity [GO:0004190]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; death receptor binding [GO:0005123]; peptidase activity [GO:0008233]; phospholipase A2 activator activity [GO:0016005]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; anterior neural tube closure [GO:0061713]; apoptotic DNA fragmentation [GO:0006309]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; axonal fasciculation [GO:0007413]; B cell homeostasis [GO:0001782]; cell fate commitment [GO:0045165]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to staurosporine [GO:0072734]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte differentiation [GO:0030218]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glial cell apoptotic process [GO:0034349]; heart development [GO:0007507]; hippo signaling [GO:0035329]; hippocampus development [GO:0021766]; intrinsic apoptotic signaling pathway in response to osmotic stress [GO:0008627]; keratinocyte differentiation [GO:0030216]; learning or memory [GO:0007611]; leukocyte apoptotic process [GO:0071887]; luteolysis [GO:0001554]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell proliferation [GO:0030889]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet formation [GO:0030220]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of neuron apoptotic process [GO:0043525]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647]; response to amino acid [GO:0043200]; response to cobalt ion [GO:0032025]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; sensory perception of sound [GO:0007605]; striated muscle cell differentiation [GO:0051146]; T cell homeostasis [GO:0043029]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; aging [GO:0007568]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; brain development [GO:0007420]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; ectopic germ cell programmed cell death [GO:0035234]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; luteolysis [GO:0001554]; negative regulation of apoptotic process [GO:0043066]; neural retina development [GO:0003407]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of neuron apoptotic process [GO:0043525]; protein processing [GO:0016485]; regulation of apoptotic process [GO:0042981]	anterior neural tube closure [GO:0061713]; apoptotic DNA fragmentation [GO:0006309]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; axonal fasciculation [GO:0007413]; B cell homeostasis [GO:0001782]; cell fate commitment [GO:0045165]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to staurosporine [GO:0072734]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte differentiation [GO:0030218]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glial cell apoptotic process [GO:0034349]; heart development [GO:0007507]; hippocampus development [GO:0021766]; hippo signaling [GO:0035329]; intrinsic apoptotic signaling pathway in response to osmotic stress [GO:0008627]; keratinocyte differentiation [GO:0030216]; learning or memory [GO:0007611]; leukocyte apoptotic process [GO:0071887]; luteolysis [GO:0001554]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell proliferation [GO:0030889]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet formation [GO:0030220]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of neuron apoptotic process [GO:0043525]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647]; response to amino acid [GO:0043200]; response to cobalt ion [GO:0032025]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; sensory perception of sound [GO:0007605]; striated muscle cell differentiation [GO:0051146]; T cell homeostasis [GO:0043029]; wound healing [GO:0042060]	aging [GO:0007568]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; brain development [GO:0007420]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; ectopic germ cell programmed cell death [GO:0035234]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; luteolysis [GO:0001554]; negative regulation of apoptotic process [GO:0043066]; neural retina development [GO:0003407]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of neuron apoptotic process [GO:0043525]; protein processing [GO:0016485]; regulation of apoptotic process [GO:0042981]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	aspartic-type endopeptidase activity [GO:0004190]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; death receptor binding [GO:0005123]; peptidase activity [GO:0008233]; phospholipase A2 activator activity [GO:0016005]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]	cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:0097200]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]
d1ri1a__d4y30b___1	Fungi	Metazoa	Microsporidia	Chordata	nucleus [GO:0005634]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; RNA binding [GO:0003723]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; histone methyltransferase activity [GO:0042054]; histone methyltransferase activity (H2A-R3 specific) [GO:0070612]; histone methyltransferase activity (H3-R2 specific) [GO:0070611]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; histone-arginine N-methyltransferase activity [GO:0008469]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; base-excision repair [GO:0006284]; cellular senescence [GO:0090398]; histone H3-R2 methylation [GO:0034970]; histone methylation [GO:0016571]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; viral process [GO:0016032]		base-excision repair [GO:0006284]; cellular senescence [GO:0090398]; histone H3-R2 methylation [GO:0034970]; histone methylation [GO:0016571]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; viral process [GO:0016032]	nucleus [GO:0005634]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; RNA binding [GO:0003723]	chromatin binding [GO:0003682]; histone-arginine N-methyltransferase activity [GO:0008469]; histone binding [GO:0042393]; histone methyltransferase activity [GO:0042054]; histone methyltransferase activity (H2A-R3 specific) [GO:0070612]; histone methyltransferase activity (H3-R2 specific) [GO:0070611]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]
d1ri7a2_d2cfxf2__1			Euryarchaeota	Firmicutes	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]					DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]
d1ri8a1_d1lvea___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]
d1ri8b__d1l90a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1riba__d3vpmb1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1ribb__d1ji4k___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1riea__d1ezve1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	
d1rihl1_d1mwaa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1riic__d2ekba___1			Actinobacteria	Deinococcus-Thermus	plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; identical protein binding [GO:0042802]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]	catalytic activity [GO:0003824]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]		plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; identical protein binding [GO:0042802]	catalytic activity [GO:0003824]
d1riid__d2owea___1			Actinobacteria	Deinococcus-Thermus	plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; identical protein binding [GO:0042802]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]	catalytic activity [GO:0003824]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]		plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; identical protein binding [GO:0042802]	catalytic activity [GO:0003824]
d1rin.1_d1xnca___1	Viridiplantae		Streptophyta	Firmicutes	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d1rirb__d2jemb___1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]
d1rirc__d3l2yl___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1rird__d5ewsi___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d1ritc__d1bjqb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]
d1ritc__d1ul9a___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]				cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1ritd__d2bw8b___1	Viridiplantae		Streptophyta	Bacteroidetes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]
d1riuh1_d1lo2l1__1		Metazoa		Chordata								
d1riuh2_d1sbbc1__1				Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1riul1_d3ngbk2__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1riul2_d4m6ml1__1												
d1rivh1_d5a16b1__1		Metazoa		Chordata								
d1rivl2_d4k3hh___1												
d1rj7a__d4ould___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; collagen trimer [GO:0005581]; cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]; death receptor agonist activity [GO:0038177]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cytokine-mediated signaling pathway [GO:0019221]; gene expression [GO:0010467]; hair follicle placode formation [GO:0060789]; immune response [GO:0006955]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of NIK/NF-kappaB signaling [GO:1901222]; salivary gland cavitation [GO:0060662]; trachea gland development [GO:0061153]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; negative regulation of cell growth [GO:0030308]; negative regulation of translation [GO:0017148]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase II [GO:0045944]	cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cytokine-mediated signaling pathway [GO:0019221]; gene expression [GO:0010467]; hair follicle placode formation [GO:0060789]; immune response [GO:0006955]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of NIK/NF-kappaB signaling [GO:1901222]; salivary gland cavitation [GO:0060662]; trachea gland development [GO:0061153]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	negative regulation of cell growth [GO:0030308]; negative regulation of translation [GO:0017148]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase II [GO:0045944]	apical part of cell [GO:0045177]; collagen trimer [GO:0005581]; cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	death receptor agonist activity [GO:0038177]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	metal ion binding [GO:0046872]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]
d1rj7d__d5kc6c1__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; collagen trimer [GO:0005581]; cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]; death receptor agonist activity [GO:0038177]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cytokine-mediated signaling pathway [GO:0019221]; gene expression [GO:0010467]; hair follicle placode formation [GO:0060789]; immune response [GO:0006955]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of NIK/NF-kappaB signaling [GO:1901222]; salivary gland cavitation [GO:0060662]; trachea gland development [GO:0061153]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic membrane [GO:0045211]; synaptic cleft [GO:0043083]; protein homodimerization activity [GO:0042803]; cerebellar granule cell differentiation [GO:0021707]; chemical synaptic transmission [GO:0007268]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of excitatory postsynaptic potential [GO:0090394]; nervous system development [GO:0007399]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; protein secretion [GO:0009306]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]	cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cytokine-mediated signaling pathway [GO:0019221]; gene expression [GO:0010467]; hair follicle placode formation [GO:0060789]; immune response [GO:0006955]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of NIK/NF-kappaB signaling [GO:1901222]; salivary gland cavitation [GO:0060662]; trachea gland development [GO:0061153]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cerebellar granule cell differentiation [GO:0021707]; chemical synaptic transmission [GO:0007268]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of excitatory postsynaptic potential [GO:0090394]; nervous system development [GO:0007399]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; protein secretion [GO:0009306]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]	apical part of cell [GO:0045177]; collagen trimer [GO:0005581]; cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic membrane [GO:0045211]; synaptic cleft [GO:0043083]	death receptor agonist activity [GO:0038177]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	protein homodimerization activity [GO:0042803]
d1rj7f__d3qbqa___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; collagen trimer [GO:0005581]; cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]; death receptor agonist activity [GO:0038177]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cytokine-mediated signaling pathway [GO:0019221]; gene expression [GO:0010467]; hair follicle placode formation [GO:0060789]; immune response [GO:0006955]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of NIK/NF-kappaB signaling [GO:1901222]; salivary gland cavitation [GO:0060662]; trachea gland development [GO:0061153]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine binding [GO:0019955]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]; tumor necrosis factor-activated receptor activity [GO:0005031]; adaptive immune response [GO:0002250]; circadian temperature homeostasis [GO:0060086]; lymph node development [GO:0048535]; mammary gland alveolus development [GO:0060749]; multicellular organism development [GO:0007275]; multinuclear osteoclast differentiation [GO:0072674]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of bone resorption [GO:0045780]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling [GO:0071848]; positive regulation of fever generation by positive regulation of prostaglandin secretion [GO:0071812]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; response to cytokine [GO:0034097]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to radiation [GO:0009314]; response to tumor necrosis factor [GO:0034612]; TNFSF11-mediated signaling pathway [GO:0071847]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cytokine-mediated signaling pathway [GO:0019221]; gene expression [GO:0010467]; hair follicle placode formation [GO:0060789]; immune response [GO:0006955]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of NIK/NF-kappaB signaling [GO:1901222]; salivary gland cavitation [GO:0060662]; trachea gland development [GO:0061153]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	adaptive immune response [GO:0002250]; circadian temperature homeostasis [GO:0060086]; lymph node development [GO:0048535]; mammary gland alveolus development [GO:0060749]; multicellular organism development [GO:0007275]; multinuclear osteoclast differentiation [GO:0072674]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of bone resorption [GO:0045780]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling [GO:0071848]; positive regulation of fever generation by positive regulation of prostaglandin secretion [GO:0071812]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; response to cytokine [GO:0034097]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to radiation [GO:0009314]; response to tumor necrosis factor [GO:0034612]; TNFSF11-mediated signaling pathway [GO:0071847]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	apical part of cell [GO:0045177]; collagen trimer [GO:0005581]; cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	death receptor agonist activity [GO:0038177]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	cytokine binding [GO:0019955]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]; tumor necrosis factor-activated receptor activity [GO:0005031]
d1rj7i__d3k48d___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; collagen trimer [GO:0005581]; cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]; death receptor agonist activity [GO:0038177]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cytokine-mediated signaling pathway [GO:0019221]; gene expression [GO:0010467]; hair follicle placode formation [GO:0060789]; immune response [GO:0006955]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of NIK/NF-kappaB signaling [GO:1901222]; salivary gland cavitation [GO:0060662]; trachea gland development [GO:0061153]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; tumor necrosis factor receptor binding [GO:0005164]; immunoglobulin mediated immune response [GO:0016064]; immunoglobulin production in mucosal tissue [GO:0002426]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of germinal center formation [GO:0002636]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of immune response [GO:0050776]	cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cytokine-mediated signaling pathway [GO:0019221]; gene expression [GO:0010467]; hair follicle placode formation [GO:0060789]; immune response [GO:0006955]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of NIK/NF-kappaB signaling [GO:1901222]; salivary gland cavitation [GO:0060662]; trachea gland development [GO:0061153]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	immunoglobulin mediated immune response [GO:0016064]; immunoglobulin production in mucosal tissue [GO:0002426]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of germinal center formation [GO:0002636]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of immune response [GO:0050776]	apical part of cell [GO:0045177]; collagen trimer [GO:0005581]; cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]	death receptor agonist activity [GO:0038177]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	cytokine activity [GO:0005125]; tumor necrosis factor receptor binding [GO:0005164]
d1rj7j__d1kd7k___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; collagen trimer [GO:0005581]; cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]; death receptor agonist activity [GO:0038177]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cytokine-mediated signaling pathway [GO:0019221]; gene expression [GO:0010467]; hair follicle placode formation [GO:0060789]; immune response [GO:0006955]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of NIK/NF-kappaB signaling [GO:1901222]; salivary gland cavitation [GO:0060662]; trachea gland development [GO:0061153]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cytokine-mediated signaling pathway [GO:0019221]; gene expression [GO:0010467]; hair follicle placode formation [GO:0060789]; immune response [GO:0006955]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of NIK/NF-kappaB signaling [GO:1901222]; salivary gland cavitation [GO:0060662]; trachea gland development [GO:0061153]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	apical part of cell [GO:0045177]; collagen trimer [GO:0005581]; cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	death receptor agonist activity [GO:0038177]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]
d1rj8f__d4nn0c1__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; collagen trimer [GO:0005581]; cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]; death receptor agonist activity [GO:0038177]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cytokine-mediated signaling pathway [GO:0019221]; gene expression [GO:0010467]; hair follicle placode formation [GO:0060789]; immune response [GO:0006955]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of NIK/NF-kappaB signaling [GO:1901222]; salivary gland cavitation [GO:0060662]; trachea gland development [GO:0061153]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell projection [GO:0042995]; collagen trimer [GO:0005581]; extracellular space [GO:0005615]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; identical protein binding [GO:0042802]; inner ear development [GO:0048839]; protein secretion [GO:0009306]	cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cytokine-mediated signaling pathway [GO:0019221]; gene expression [GO:0010467]; hair follicle placode formation [GO:0060789]; immune response [GO:0006955]; odontogenesis of dentin-containing tooth [GO:0042475]; pigmentation [GO:0043473]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of NIK/NF-kappaB signaling [GO:1901222]; salivary gland cavitation [GO:0060662]; trachea gland development [GO:0061153]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	inner ear development [GO:0048839]; protein secretion [GO:0009306]	apical part of cell [GO:0045177]; collagen trimer [GO:0005581]; cytoskeleton [GO:0005856]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell projection [GO:0042995]; collagen trimer [GO:0005581]; extracellular space [GO:0005615]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	death receptor agonist activity [GO:0038177]; death receptor binding [GO:0005123]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	identical protein binding [GO:0042802]
d1rj9a2_d1m34p___1			Deinococcus-Thermus	Proteobacteria	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	nitrogen fixation [GO:0009399]	signal recognition particle [GO:0048500]	molybdenum-iron nitrogenase complex [GO:0016612]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1rjea1_d3kqvb1__1	Fungi	Metazoa	Ascomycota	Chordata	protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; C-terminal protein methylation [GO:0006481]; cellular protein-containing complex assembly [GO:0034622]; regulation of autophagy [GO:0010506]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cellular protein-containing complex assembly [GO:0034622]; C-terminal protein methylation [GO:0006481]; regulation of autophagy [GO:0010506]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d1rjec1_d1qaqa___1	Fungi		Ascomycota	Firmicutes	protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; C-terminal protein methylation [GO:0006481]; cellular protein-containing complex assembly [GO:0034622]; regulation of autophagy [GO:0010506]	23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity [GO:0052910]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]; response to antibiotic [GO:0046677]	cellular protein-containing complex assembly [GO:0034622]; C-terminal protein methylation [GO:0006481]; regulation of autophagy [GO:0010506]	response to antibiotic [GO:0046677]			protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]	23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity [GO:0052910]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]
d1rjjb__d1tr0x___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; cytosol [GO:0005829]; plastid [GO:0009536]; metal ion binding [GO:0046872]				chloroplast [GO:0009507]; cytosol [GO:0005829]; plastid [GO:0009536]		metal ion binding [GO:0046872]	
d1rjla2_d12e8p2__1			Spirochaetes		cell outer membrane [GO:0009279]; membrane [GO:0016020]				cell outer membrane [GO:0009279]; membrane [GO:0016020]			
d1rjra3_d3hkab___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; N-acyl-D-amino-acid deacylase activity [GO:0047420]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]; N-acyl-D-amino-acid deacylase activity [GO:0047420]	metal ion binding [GO:0046872]
d1rjwb2_d1gufa2__1		Fungi	Firmicutes	Ascomycota	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		mitochondrion [GO:0005739]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]
d1rjwb2_d2x6ti___1			Firmicutes	Proteobacteria	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; membrane [GO:0016020]; ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]		ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]		cytosol [GO:0005829]; membrane [GO:0016020]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]
d1rjwd2_d1p1rb2__1		Metazoa	Firmicutes	Chordata	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1rjwd2_d4fj2d___1		Fungi	Firmicutes	Ascomycota	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]					alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1rjyb1_d4y16c1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1rjyd1_d4l1ha___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]
d1rjza1_d3juyc2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1rjzd2_d4ozfa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1rjze1_d3tm6e1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rk0a1_d1e28a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rk1b__d4evnl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1rk1b__d5itbl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1rk2d__d1wyea___1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	D-ribose catabolic process [GO:0019303]		cytosol [GO:0005829]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]
d1rk4a1_d4ofmd2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	transferase activity [GO:0016740]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]		blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]		cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	transferase activity [GO:0016740]
d1rkea2_d1rkca1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; membrane raft [GO:0045121]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; terminal web [GO:1990357]; zonula adherens [GO:0005915]; actin binding [GO:0003779]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]; adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; muscle contraction [GO:0006936]; negative regulation of cell migration [GO:0030336]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; protein localization to cell surface [GO:0034394]	adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; membrane raft [GO:0045121]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; terminal web [GO:1990357]; zonula adherens [GO:0005915]; actin binding [GO:0003779]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]; adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; muscle contraction [GO:0006936]; negative regulation of cell migration [GO:0030336]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; protein localization to cell surface [GO:0034394]	adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; muscle contraction [GO:0006936]; negative regulation of cell migration [GO:0030336]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; protein localization to cell surface [GO:0034394]	adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; muscle contraction [GO:0006936]; negative regulation of cell migration [GO:0030336]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; protein localization to cell surface [GO:0034394]	adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; membrane raft [GO:0045121]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; terminal web [GO:1990357]; zonula adherens [GO:0005915]	adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; membrane raft [GO:0045121]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; terminal web [GO:1990357]; zonula adherens [GO:0005915]	actin binding [GO:0003779]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]	actin binding [GO:0003779]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]
d1rkja2_d5lsld___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; ribonucleoprotein complex [GO:1990904]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]	nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]; RNA binding [GO:0003723]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; ribonucleoprotein complex [GO:1990904]	nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]	RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]	RNA binding [GO:0003723]
d1rkma__d2f36b___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	protein transport [GO:0015031]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	peptide transmembrane transporter activity [GO:1904680]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d1rkqa1_d4bnda1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	cytoplasm [GO:0005737]; phosphomannomutase activity [GO:0004615]; GDP-mannose biosynthetic process [GO:0009298]		GDP-mannose biosynthetic process [GO:0009298]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	phosphomannomutase activity [GO:0004615]
d1rkrb__d4knuf2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1rkrd__d2tsbb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1rkub1_d3mn1j1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4-amino-4-deoxychorismate synthase activity [GO:0046820]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; phosphoserine phosphatase activity [GO:0004647]; phosphoserine:homoserine phosphotransferase activity [GO:0043899]; dephosphorylation [GO:0016311]; L-serine biosynthetic process [GO:0006564]; phosphorylation [GO:0016310]; tetrahydrofolate biosynthetic process [GO:0046654]; threonine biosynthetic process [GO:0009088]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	dephosphorylation [GO:0016311]; L-serine biosynthetic process [GO:0006564]; phosphorylation [GO:0016310]; tetrahydrofolate biosynthetic process [GO:0046654]; threonine biosynthetic process [GO:0009088]	lipopolysaccharide biosynthetic process [GO:0009103]	cytoplasm [GO:0005737]		4-amino-4-deoxychorismate synthase activity [GO:0046820]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; phosphoserine:homoserine phosphotransferase activity [GO:0043899]; phosphoserine phosphatase activity [GO:0004647]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1rkwe1_d5mymb1__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d1rl3a1_d1u12a___1	Metazoa		Chordata	Proteobacteria	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]		axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]
d1rl3a1_d3ukna___1	Metazoa	Metazoa	Chordata	Chordata	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	integral component of plasma membrane [GO:0005887]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]; potassium ion transmembrane transporter activity [GO:0015079]; voltage-gated potassium channel activity [GO:0005249]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]	cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]	integral component of plasma membrane [GO:0005887]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]; potassium ion transmembrane transporter activity [GO:0015079]; voltage-gated potassium channel activity [GO:0005249]
d1rl3a2_d2beoa2__1	Metazoa		Chordata	Firmicutes	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; pathogenesis [GO:0009405]	cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	pathogenesis [GO:0009405]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]		3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1rl8a__d2pwra___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1rl8b__d4njud___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1rlaa__d3th7b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1rlba__d3cn1a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1rlbd__d1ttab___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1rlbd__d2igld1__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	periplasmic space [GO:0042597]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]
d1rlbf__d1towa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1rlcs__d1upmw___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rlds__d2ybvp___1	Viridiplantae		Streptophyta	Cyanobacteria	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	
d1rlea7_d1ex0a2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]		blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]		metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1rlfa__d4nawa___1	Metazoa	Metazoa	Chordata	Chordata	Rho guanyl-nucleotide exchange factor activity [GO:0005089]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of Ral protein signal transduction [GO:0032485]; small GTPase mediated signal transduction [GO:0007264]	Atg12-Atg5-Atg16 complex [GO:0034274]; autophagosome [GO:0005776]; axoneme [GO:0005930]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; phagocytic vesicle membrane [GO:0030670]; phagophore assembly site membrane [GO:0034045]; aggrephagy [GO:0035973]; antigen processing and presentation of endogenous antigen [GO:0019883]; apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; blood vessel remodeling [GO:0001974]; C-terminal protein lipidation [GO:0006501]; cellular homeostasis [GO:0019725]; cellular response to nitrogen starvation [GO:0006995]; cellular response to nitrosative stress [GO:0071500]; heart contraction [GO:0060047]; macroautophagy [GO:0016236]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative stranded viral RNA replication [GO:0039689]; negative thymic T cell selection [GO:0045060]; otolith development [GO:0048840]; positive regulation by symbiont of host autophagy [GO:0075044]; positive regulation of mucus secretion [GO:0070257]; post-translational protein modification [GO:0043687]; protein lipidation involved in autophagosome assembly [GO:0061739]; regulation of cilium assembly [GO:1902017]; regulation of cytokine secretion involved in immune response [GO:0002739]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to drug [GO:0042493]; response to fungus [GO:0009620]; vasodilation [GO:0042311]; ventricular cardiac muscle cell development [GO:0055015]	negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of Ral protein signal transduction [GO:0032485]; small GTPase mediated signal transduction [GO:0007264]	aggrephagy [GO:0035973]; antigen processing and presentation of endogenous antigen [GO:0019883]; apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; blood vessel remodeling [GO:0001974]; cellular homeostasis [GO:0019725]; cellular response to nitrogen starvation [GO:0006995]; cellular response to nitrosative stress [GO:0071500]; C-terminal protein lipidation [GO:0006501]; heart contraction [GO:0060047]; macroautophagy [GO:0016236]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative stranded viral RNA replication [GO:0039689]; negative thymic T cell selection [GO:0045060]; otolith development [GO:0048840]; positive regulation by symbiont of host autophagy [GO:0075044]; positive regulation of mucus secretion [GO:0070257]; post-translational protein modification [GO:0043687]; protein lipidation involved in autophagosome assembly [GO:0061739]; regulation of cilium assembly [GO:1902017]; regulation of cytokine secretion involved in immune response [GO:0002739]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to drug [GO:0042493]; response to fungus [GO:0009620]; vasodilation [GO:0042311]; ventricular cardiac muscle cell development [GO:0055015]		Atg12-Atg5-Atg16 complex [GO:0034274]; autophagosome [GO:0005776]; axoneme [GO:0005930]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; phagocytic vesicle membrane [GO:0030670]; phagophore assembly site membrane [GO:0034045]	Rho guanyl-nucleotide exchange factor activity [GO:0005089]	
d1rlka__d1xtyb___1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	aminoacyl-tRNA hydrolase activity [GO:0004045]	aminoacyl-tRNA hydrolase activity [GO:0004045]
d1rlla3_d1bl2a4__1												
d1rlla4_d1evub2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]		blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]		metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1rllb1_d4pygb1__1		Metazoa		Chordata		cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]		apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]		cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1rllb2_d2r9ob___1		Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d1rlmc__d2r8yb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]		magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1rltb__d4um7a1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]		magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1rltc__d4knwc___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	cytosol [GO:0005829]; N-acylneuraminate-9-phosphatase activity [GO:0050124]; carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine biosynthetic process [GO:0006045]; N-acetylneuraminate biosynthetic process [GO:0046380]		carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine biosynthetic process [GO:0006045]; N-acetylneuraminate biosynthetic process [GO:0046380]	cytosol [GO:0005829]	cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	N-acylneuraminate-9-phosphatase activity [GO:0050124]
d1rlvb1_d1a79d1__1			Euryarchaeota	Euryarchaeota	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	tRNA-intron endonuclease complex [GO:0000214]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]; tRNA-type intron splice site recognition and cleavage [GO:0000379]	tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	tRNA-type intron splice site recognition and cleavage [GO:0000379]		tRNA-intron endonuclease complex [GO:0000214]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; tRNA-intron endonuclease activity [GO:0000213]
d1rlwa__d3kwua1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; calcium-dependent phospholipid binding [GO:0005544]; lysophospholipase activity [GO:0004622]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; cardiolipin acyl-chain remodeling [GO:0035965]; cellular response to antibiotic [GO:0071236]; glycerophospholipid catabolic process [GO:0046475]; icosanoid biosynthetic process [GO:0046456]; icosanoid metabolic process [GO:0006690]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; platelet activating factor biosynthetic process [GO:0006663]; regulation of cell population proliferation [GO:0042127]		arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; cardiolipin acyl-chain remodeling [GO:0035965]; cellular response to antibiotic [GO:0071236]; glycerophospholipid catabolic process [GO:0046475]; icosanoid biosynthetic process [GO:0046456]; icosanoid metabolic process [GO:0006690]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; platelet activating factor biosynthetic process [GO:0006663]; regulation of cell population proliferation [GO:0042127]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]		calcium-dependent phospholipase A2 activity [GO:0047498]; calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; lysophospholipase activity [GO:0004622]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]	
d1rm3a2_d2pkqo2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1rm6b1_d3nvvk2__1		Metazoa	Proteobacteria	Chordata	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1rm6c2_d4jx1d___1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1rm6e1_d3bdjb4__1		Metazoa	Proteobacteria	Chordata	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1rm6f1_d1jrpc1__1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1rm6f2_d2y5ca1__1		Metazoa	Proteobacteria	Chordata	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	mitochondrial matrix [GO:0005759]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; C21-steroid hormone biosynthetic process [GO:0006700]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]		C21-steroid hormone biosynthetic process [GO:0006700]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]		mitochondrial matrix [GO:0005759]	4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1rm7c__d3mn1i1__1				Proteobacteria		3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]				3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1rmfl2_d2eytd2__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1rmfl2_d5vxjj___1				Proteobacteria		extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]		
d1rmga__d2iq7g___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	polygalacturonase activity [GO:0004650]
d1rmha__d4j5ba___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]
d1rmhb__d2z6wa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]
d1rmqb__d2i54b___1			Proteobacteria		outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]; GDP-mannose biosynthetic process [GO:0009298]		GDP-mannose biosynthetic process [GO:0009298]	outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]	acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]
d1rmtb__d2r8yk___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]	outer membrane-bounded periplasmic space [GO:0030288]		acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1rmu3__d5nedc___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1rn1b__d1t2hb___1	Fungi		Ascomycota	Actinobacteria	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1rnfa1_d1o0ob___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]; mRNA cleavage [GO:0006379]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	mRNA cleavage [GO:0006379]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1rnqa__d1d5d.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1ro6b__d3sl3c___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d1roaa__d2w9qa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cysteine-type endopeptidase inhibitor activity [GO:0004869]	cysteine-type endopeptidase inhibitor activity [GO:0004869]			extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cysteine-type endopeptidase inhibitor activity [GO:0004869]	cysteine-type endopeptidase inhibitor activity [GO:0004869]
d1roea__d1zcsa5__1			Cyanobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	
d1rorb__d2hd1b___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1rorb__d5axpa___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d1rosa__d1bqoa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1rosb__d2tcla___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1roua__d3kaia2__1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; cytosol [GO:0005829]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; tau protein binding [GO:0048156]; chaperone-mediated protein folding [GO:0061077]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	chaperone-mediated protein folding [GO:0061077]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	axonal growth cone [GO:0044295]; cytosol [GO:0005829]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; tau protein binding [GO:0048156]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]
d1roxa__d2h1xc___1		Metazoa		Chordata		peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1rp0a1_d1djnb2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; plastid [GO:0009536]; stromule [GO:0010319]; thylakoid [GO:0009579]; iron ion binding [GO:0005506]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; transferase activity, transferring pentosyl groups [GO:0016763]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; oxazole or thiazole biosynthetic process [GO:0018131]; response to cold [GO:0009409]; thiamine biosynthetic process [GO:0009228]; thiazole biosynthetic process [GO:0052837]	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	cellular response to DNA damage stimulus [GO:0006974]; oxazole or thiazole biosynthetic process [GO:0018131]; response to cold [GO:0009409]; thiamine biosynthetic process [GO:0009228]; thiazole biosynthetic process [GO:0052837]		chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; plastid [GO:0009536]; stromule [GO:0010319]; thylakoid [GO:0009579]		iron ion binding [GO:0005506]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; transferase activity, transferring pentosyl groups [GO:0016763]; zinc ion binding [GO:0008270]	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]
d1rp0b__d1ndac1__1	Viridiplantae		Streptophyta		chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; plastid [GO:0009536]; stromule [GO:0010319]; thylakoid [GO:0009579]; iron ion binding [GO:0005506]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; transferase activity, transferring pentosyl groups [GO:0016763]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; oxazole or thiazole biosynthetic process [GO:0018131]; response to cold [GO:0009409]; thiamine biosynthetic process [GO:0009228]; thiazole biosynthetic process [GO:0052837]	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]; cell redox homeostasis [GO:0045454]	cellular response to DNA damage stimulus [GO:0006974]; oxazole or thiazole biosynthetic process [GO:0018131]; response to cold [GO:0009409]; thiamine biosynthetic process [GO:0009228]; thiazole biosynthetic process [GO:0052837]	cell redox homeostasis [GO:0045454]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; plastid [GO:0009536]; stromule [GO:0010319]; thylakoid [GO:0009579]	cell [GO:0005623]; cytoplasm [GO:0005737]	iron ion binding [GO:0005506]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; transferase activity, transferring pentosyl groups [GO:0016763]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]
d1rp3a3_d2be5f3__1			Aquificae	Deinococcus-Thermus	sigma factor antagonist complex [GO:1903865]; antisigma factor binding [GO:0045152]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; sigma factor activity [GO:0016987]; DNA-templated transcription, initiation [GO:0006352]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	DNA-templated transcription, initiation [GO:0006352]	transcription, DNA-templated [GO:0006351]	sigma factor antagonist complex [GO:1903865]		antisigma factor binding [GO:0045152]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; sigma factor activity [GO:0016987]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d1rp7b3_d3exib2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1rp8a2_d5manb1__1	Viridiplantae		Streptophyta	Actinobacteria	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	sucrose phosphorylase activity [GO:0009018]; cellular carbohydrate metabolic process [GO:0044262]	carbohydrate metabolic process [GO:0005975]	cellular carbohydrate metabolic process [GO:0044262]	extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	sucrose phosphorylase activity [GO:0009018]
d1rpla2_d7icua4__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d1rpma__d1ohea1__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; neuron projection development [GO:0031175]; positive regulation of blood vessel diameter [GO:0097755]; protein dephosphorylation [GO:0006470]; response to drug [GO:0042493]; retina layer formation [GO:0010842]; retinal ganglion cell axon guidance [GO:0031290]; signal transduction [GO:0007165]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cilium assembly [GO:0060271]; DNA repair [GO:0006281]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; mitotic cell cycle arrest [GO:0071850]; positive regulation of cytokinesis [GO:0032467]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; neuron projection development [GO:0031175]; positive regulation of blood vessel diameter [GO:0097755]; protein dephosphorylation [GO:0006470]; response to drug [GO:0042493]; retina layer formation [GO:0010842]; retinal ganglion cell axon guidance [GO:0031290]; signal transduction [GO:0007165]	cilium assembly [GO:0060271]; DNA repair [GO:0006281]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; mitotic cell cycle arrest [GO:0071850]; positive regulation of cytokinesis [GO:0032467]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1rpmb__d2zn7a___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; neuron projection development [GO:0031175]; positive regulation of blood vessel diameter [GO:0097755]; protein dephosphorylation [GO:0006470]; response to drug [GO:0042493]; retina layer formation [GO:0010842]; retinal ganglion cell axon guidance [GO:0031290]; signal transduction [GO:0007165]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; neuron projection development [GO:0031175]; positive regulation of blood vessel diameter [GO:0097755]; protein dephosphorylation [GO:0006470]; response to drug [GO:0042493]; retina layer formation [GO:0010842]; retinal ganglion cell axon guidance [GO:0031290]; signal transduction [GO:0007165]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1rpqd2_d1fcga2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]	Fc-epsilon receptor signaling pathway [GO:0038095]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	IgE binding [GO:0019863]	IgG binding [GO:0019864]
d1rpsb__d5cnea___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1rpsd__d1a3oa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1rpsd__d4f0ta___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1rpwa1_d5f1ja1__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d1rpwd1_d5fkna1__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d1rpxa__d1losa___1	Viridiplantae		Streptophyta	Euryarchaeota	chloroplast thylakoid membrane [GO:0009535]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	chloroplast thylakoid membrane [GO:0009535]		metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1rpxb__d3v1pa___1	Viridiplantae		Streptophyta	Euryarchaeota	chloroplast thylakoid membrane [GO:0009535]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	chloroplast thylakoid membrane [GO:0009535]		metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1rq7a2_d4o4jd2__1		Metazoa	Actinobacteria	Chordata	cell division site [GO:0032153]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; positive regulation of cell cycle [GO:0045787]; protein polymerization [GO:0051258]; septin ring assembly [GO:0000921]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; positive regulation of cell cycle [GO:0045787]; protein polymerization [GO:0051258]; septin ring assembly [GO:0000921]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell division site [GO:0032153]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1rq9b__d4gb2b___1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1rqab__d2uumh___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1rqab__d4esad___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1rqad__d2xyka___1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d1rqda__d1yc2a___1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; deoxyhypusine synthase activity [GO:0034038]; identical protein binding [GO:0042802]; peptidyl-lysine modification to peptidyl-hypusine [GO:0008612]; positive regulation of cell population proliferation [GO:0008284]; spermidine metabolic process [GO:0008216]; translation [GO:0006412]	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	peptidyl-lysine modification to peptidyl-hypusine [GO:0008612]; positive regulation of cell population proliferation [GO:0008284]; spermidine metabolic process [GO:0008216]; translation [GO:0006412]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	deoxyhypusine synthase activity [GO:0034038]; identical protein binding [GO:0042802]	NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d1rqga1_d4mvwb2__1			Euryarchaeota		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; methionyl-tRNA aminoacylation [GO:0006431]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]
d1rqla__d1ys9a1__1			Firmicutes	Firmicutes	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]		organic phosphonate catabolic process [GO:0019700]				magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]	
d1rqlb__d2b8ja___1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	organic phosphonate catabolic process [GO:0019700]			outer membrane-bounded periplasmic space [GO:0030288]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]	acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]
d1rqnb__d5ue7b___1		Fungi	Firmicutes	Ascomycota	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	cytosol [GO:0005829]; fungal biofilm matrix [GO:0062040]; phosphomannomutase activity [GO:0004615]; GDP-mannose biosynthetic process [GO:0009298]; mannose metabolic process [GO:0006013]; protein N-linked glycosylation [GO:0006487]; protein targeting to ER [GO:0045047]	organic phosphonate catabolic process [GO:0019700]	GDP-mannose biosynthetic process [GO:0009298]; mannose metabolic process [GO:0006013]; protein N-linked glycosylation [GO:0006487]; protein targeting to ER [GO:0045047]		cytosol [GO:0005829]; fungal biofilm matrix [GO:0062040]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]	phosphomannomutase activity [GO:0004615]
d1rqpb2_d2v7wb2__1			Actinobacteria	Actinobacteria	adenosyl-fluoride synthase activity [GO:0033846]	adenosyl-fluoride synthase activity [GO:0033846]					adenosyl-fluoride synthase activity [GO:0033846]	adenosyl-fluoride synthase activity [GO:0033846]
d1rqxc__d2jc3c___1			Proteobacteria	Proteobacteria	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; 1-aminocyclopropane-1-carboxylate metabolic process [GO:0018871]; amine catabolic process [GO:0009310]	cytoplasm [GO:0005737]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	1-aminocyclopropane-1-carboxylate metabolic process [GO:0018871]; amine catabolic process [GO:0009310]	cysteine biosynthetic process from serine [GO:0006535]		cytoplasm [GO:0005737]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]
d1rr5a__d2g64a1__1		Metazoa		Nematoda (roundworms)		mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; tetrahydrobiopterin biosynthetic process [GO:0006729]		tetrahydrobiopterin biosynthetic process [GO:0006729]		mitochondrion [GO:0005739]		6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1rrha2_d2pvsb2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; oxylipin biosynthetic process [GO:0031408]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; 1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity [GO:0102549]; acylglycerol lipase activity [GO:0047372]; calcium ion binding [GO:0005509]; galactolipase activity [GO:0047714]; lipase activity [GO:0016298]; phospholipase activity [GO:0004620]; triglyceride lipase activity [GO:0004806]; cellular defense response [GO:0006968]; galactolipid catabolic process [GO:0019376]; intestinal lipid catabolic process [GO:0044258]; lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241]; phospholipid catabolic process [GO:0009395]; response to bacterium [GO:0009617]; triglyceride metabolic process [GO:0006641]	oxylipin biosynthetic process [GO:0031408]	cellular defense response [GO:0006968]; galactolipid catabolic process [GO:0019376]; intestinal lipid catabolic process [GO:0044258]; lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241]; phospholipid catabolic process [GO:0009395]; response to bacterium [GO:0009617]; triglyceride metabolic process [GO:0006641]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]	1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity [GO:0102549]; acylglycerol lipase activity [GO:0047372]; calcium ion binding [GO:0005509]; galactolipase activity [GO:0047714]; lipase activity [GO:0016298]; phospholipase activity [GO:0004620]; triglyceride lipase activity [GO:0004806]
d1rria__d2yzea1__1			Firmicutes	Actinobacteria	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]			dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]	urate oxidase activity [GO:0004846]
d1rrta3_d1mpgb1__1				Proteobacteria		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1rs2a__d1b9lf___1			Firmicutes	Proteobacteria	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]; folic acid-containing compound metabolic process [GO:0006760]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]		cytosol [GO:0005829]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]	dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]
d1rs4a__d1j2gb1__1			Firmicutes	Firmicutes	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]; allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]			dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]
d1rscb2_d1rblb2__1			Cyanobacteria	Cyanobacteria	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]			monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rscb2_d5kozk1__1			Cyanobacteria	Proteobacteria	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]			monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rscc2_d5hjxe1__1			Cyanobacteria	Proteobacteria	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]			monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rscf2_d5koza1__1			Cyanobacteria	Proteobacteria	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]			monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rsch2_d1rbob2__1		Viridiplantae	Cyanobacteria	Streptophyta	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rsci__d4rubt___1		Viridiplantae	Cyanobacteria	Streptophyta	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		chloroplast [GO:0009507]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rscm__d1iwab___1			Cyanobacteria	Rhodophyta	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	reductive pentose-phosphate cycle [GO:0019253]			chloroplast [GO:0009507]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	
d1rsco__d1wddw___1		Viridiplantae	Cyanobacteria	Streptophyta	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1rsfa1_d1qsee1__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rsfa1_d4m7jl2__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d1rsia__d1a9ci___1			Firmicutes	Proteobacteria	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1rsna__d1hz1a___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1rsna__d1ucla___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1rsnb__d1mgwa___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1rsvb__d4xksg___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1rsya1_d5h4za___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	axon [GO:0030424]; cell junction [GO:0030054]; dense core granule [GO:0031045]; exocytic vesicle [GO:0070382]; integral component of neuronal dense core vesicle membrane [GO:0099066]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; proximal neuron projection [GO:1990769]; recycling endosome membrane [GO:0055038]; synaptic vesicle membrane [GO:0030672]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; clathrin binding [GO:0030276]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein heterodimerization activity [GO:0046982]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; vesicle-mediated transport [GO:0016192]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; vesicle-mediated transport [GO:0016192]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	axon [GO:0030424]; cell junction [GO:0030054]; dense core granule [GO:0031045]; exocytic vesicle [GO:0070382]; integral component of neuronal dense core vesicle membrane [GO:0099066]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; proximal neuron projection [GO:1990769]; recycling endosome membrane [GO:0055038]; synaptic vesicle membrane [GO:0030672]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; clathrin binding [GO:0030276]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein heterodimerization activity [GO:0046982]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]
d1rt1a1_d2vg6a2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1rt9a__d1xe3d1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	purine nucleoside metabolic process [GO:0042278]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]		drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d1rtf.1_d3m35a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; phosphoprotein binding [GO:0051219]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; blood coagulation [GO:0007596]; cellular protein modification process [GO:0006464]; fibrinolysis [GO:0042730]; negative regulation of proteolysis [GO:0045861]; plasminogen activation [GO:0031639]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; proteolysis [GO:0006508]; response to hypoxia [GO:0001666]; smooth muscle cell migration [GO:0014909]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; cellular protein modification process [GO:0006464]; fibrinolysis [GO:0042730]; negative regulation of proteolysis [GO:0045861]; plasminogen activation [GO:0031639]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; proteolysis [GO:0006508]; response to hypoxia [GO:0001666]; smooth muscle cell migration [GO:0014909]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]	digestion [GO:0007586]; proteolysis [GO:0006508]	apical part of cell [GO:0045177]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	phosphoprotein binding [GO:0051219]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1rtia1_d3nh2b___1				Proteobacteria	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]; 3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d1rtja1_d4hufb___1				Firmicutes	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1rtm21_d4gk1d___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d1rtva1_d3rykb1__1			Proteobacteria	Firmicutes	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; O antigen biosynthetic process [GO:0009243]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dTDP-rhamnose biosynthetic process [GO:0019305]; O antigen biosynthetic process [GO:0009243]			dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d1rtxa__d3dhra___1		Metazoa	Cyanobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]		cell [GO:0005623]; cytoplasm [GO:0005737]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ru0a__d3hxab___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; nucleus [GO:0005634]; 4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; identical protein binding [GO:0042802]; phenylalanine 4-monooxygenase activity [GO:0004505]; positive regulation of transcription, DNA-templated [GO:0045893]; tetrahydrobiopterin biosynthetic process [GO:0006729]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; identical protein binding [GO:0042802]; phenylalanine 4-monooxygenase activity [GO:0004505]; transcription coactivator activity [GO:0003713]; L-phenylalanine metabolic process [GO:0006558]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of protein binding [GO:0043393]; tetrahydrobiopterin biosynthetic process [GO:0006729]	positive regulation of transcription, DNA-templated [GO:0045893]; tetrahydrobiopterin biosynthetic process [GO:0006729]	L-phenylalanine metabolic process [GO:0006558]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of protein binding [GO:0043393]; tetrahydrobiopterin biosynthetic process [GO:0006729]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; identical protein binding [GO:0042802]; phenylalanine 4-monooxygenase activity [GO:0004505]	4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; identical protein binding [GO:0042802]; phenylalanine 4-monooxygenase activity [GO:0004505]; transcription coactivator activity [GO:0003713]
d1ru0b__d1usob___1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrion [GO:0005739]; nucleus [GO:0005634]; 4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; identical protein binding [GO:0042802]; phenylalanine 4-monooxygenase activity [GO:0004505]; positive regulation of transcription, DNA-templated [GO:0045893]; tetrahydrobiopterin biosynthetic process [GO:0006729]	4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; tetrahydrobiopterin biosynthetic process [GO:0006729]	positive regulation of transcription, DNA-templated [GO:0045893]; tetrahydrobiopterin biosynthetic process [GO:0006729]	tetrahydrobiopterin biosynthetic process [GO:0006729]	mitochondrion [GO:0005739]; nucleus [GO:0005634]		4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]; identical protein binding [GO:0042802]; phenylalanine 4-monooxygenase activity [GO:0004505]	4-alpha-hydroxytetrahydrobiopterin dehydratase activity [GO:0008124]
d1ru4a__d1o8da___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]
d1ru7a__d4cywe___1			Negarnaviricota	Negarnaviricota	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1ru7k__d5bnyc___1			Negarnaviricota	Negarnaviricota	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rual1_d3d9al2__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1rual1_d4idla___1	Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d1rud3__d1auya___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1rue1__d4y5z4___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1rue.1_d4y5zf___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1rue1__d5d8ac___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ruf3__d4rqpg___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1rug.1_d1c8nb___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1rug1__d1rui1___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ruh1__d4y4yz___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1rui.1_d4cewc___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1ruj.1_d4cdwa___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1rukh2_d4hbqa2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; integrin binding involved in cell-matrix adhesion [GO:0098640]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	integrin binding involved in cell-matrix adhesion [GO:0098640]
d1rukl1_d2jcca1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rukl1_d3qeud1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1rukl2_d2jccm2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rulh2_d3wfdl1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]; aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]
d1rull1_d3give1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rumh1_d4nqdg1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rumh2_d1qfuh2__1	Metazoa		Chordata	Negarnaviricota	metal ion binding [GO:0046872]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]	host cell surface receptor binding [GO:0046789]
d1rumh2_d4h8wc1__1	Metazoa		Chordata		metal ion binding [GO:0046872]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]	structural molecule activity [GO:0005198]
d1ruml1_d3dvia___1	Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d1ruml1_d3scmd1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	metal ion binding [GO:0046872]	
d1ruoa2_d1hw5b2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d1ruph2_d2a0ld1__1	Metazoa		Chordata	Crenarchaeota	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]; regulation of ion transmembrane transport [GO:0034765]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	regulation of ion transmembrane transport [GO:0034765]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	voltage-gated potassium channel complex [GO:0008076]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1ruqh1_d1h3ua1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ruql1_d4pj5h2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rurh1_d5u16b___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rurl1_d4l4vd2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ruzl__d4mhii1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1ruzl__d4w8ne___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rv0h__d5t0ba___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rv0l__d4n5zi1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rv0l__d5br0c___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rv1b__d3fdoa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; 5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]
d1rv7b__d1fg6c___1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1rvaa__d2gied___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]
d1rvea__d1bhmb___1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]
d1rvf.1_d4sbva___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; calcium ion binding [GO:0005509]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	calcium ion binding [GO:0005509]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]
d1rvf1__d5a33b1__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	transport of virus in host, cell to cell [GO:0046740]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1rvf1__d5ner3___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell junction [GO:0030054]; centrosome [GO:0005813]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alphav-beta6 complex [GO:0034685]; integrin complex [GO:0008305]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; regulation of transforming growth factor beta activation [GO:1901388]; transforming growth factor-beta secretion [GO:0038044]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; regulation of transforming growth factor beta activation [GO:1901388]; transforming growth factor-beta secretion [GO:0038044]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cell junction [GO:0030054]; centrosome [GO:0005813]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alphav-beta6 complex [GO:0034685]; integrin complex [GO:0008305]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]
d1rvf3__d4y4yw___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1rvfh__d5d7if1__1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rvfl__d1vscb2__1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell chemotaxis [GO:0060326]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]
d1rvgd__d4s1fs1__1			Deinococcus-Thermus	Proteobacteria	fructose-bisphosphate aldolase activity [GO:0004332]; zinc ion binding [GO:0008270]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	fructose 1,6-bisphosphate metabolic process [GO:0030388]; glycolytic process [GO:0006096]	fructose metabolic process [GO:0006000]		cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]; zinc ion binding [GO:0008270]	fructose 6-phosphate aldolase activity [GO:0097023]
d1rvth__d4ln8c___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d1rvtl__d4cyzc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rvv1__d1xn1a___1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1rvvb__d4j07e___1			Firmicutes	Actinobacteria	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1rvvc__d4j07d___1			Firmicutes	Actinobacteria	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1rvvk__d1nqud___1			Firmicutes	Aquificae	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1rvvm__d4kq6d___1		Fungi	Firmicutes	Ascomycota	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	mitochondrial intermembrane space [GO:0005758]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	mitochondrial intermembrane space [GO:0005758]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1rvvp__d1nqua___1			Firmicutes	Aquificae	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1rvvq__d1nqwa___1			Firmicutes	Aquificae	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1rvvs__d4gefh___1			Firmicutes		cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]		cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]		6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	
d1rvwa__d5cnba___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1rvwb__d4mqkf___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1rvxg__d2wrca1__1			Negarnaviricota	Negarnaviricota	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rvxg__d4cyza___1			Negarnaviricota	Negarnaviricota	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rvxk__d5vmjc___1			Negarnaviricota	Negarnaviricota	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rvzc__d4cyva___1			Negarnaviricota	Negarnaviricota	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rvzc__d4k65a1__1			Negarnaviricota	Negarnaviricota	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rvzi__d4n5zs1__1			Negarnaviricota	Negarnaviricota	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rvzi__d5thca___1			Negarnaviricota	Negarnaviricota	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rvzk__d4cqra___1			Negarnaviricota	Negarnaviricota	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of viral protein in host cell [GO:0019060]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of immune response [GO:0050776]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome packaging [GO:0019072]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d1rw0a__d1rv9a___1			Proteobacteria	Proteobacteria	oxidoreductase activity [GO:0016491]	copper ion binding [GO:0005507]					oxidoreductase activity [GO:0016491]	copper ion binding [GO:0005507]
d1rw4a__d4jyba___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	GTP binding [GO:0005525]; GTPase activity [GO:0003924]	nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1rw9a3_d1jyna4__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1rwbe__d3itda___1		Fungi	Firmicutes	Ascomycota	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; sporulation resulting in formation of a cellular spore [GO:0030435]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	sporulation resulting in formation of a cellular spore [GO:0030435]				glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1rwfa1_d4e1yb1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]; carbohydrate metabolic process [GO:0005975]	periplasmic space [GO:0042597]; lyase activity [GO:0016829]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	periplasmic space [GO:0042597]	carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]	lyase activity [GO:0016829]
d1rwfa3_d3vdcb5__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1rwha3_d3muz15__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1rwm.1_d1f9e.2__1	Metazoa	Metazoa	Chordata	Chordata	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; IPAF inflammasome complex [GO:0072557]; NLRP1 inflammasome complex [GO:0072558]; NLRP3 inflammasome complex [GO:0072559]; plasma membrane [GO:0005886]; protease inhibitor complex [GO:0097179]; protein-containing complex [GO:0032991]; CARD domain binding [GO:0050700]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to cytokine stimulus [GO:0071345]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ripoptosome [GO:0097342]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type peptidase activity [GO:0008234]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; death-inducing signaling complex assembly [GO:0071550]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macrophage differentiation [GO:0030225]; natural killer cell activation [GO:0030101]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of proteolysis [GO:0045862]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of necroptotic process [GO:0060544]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039650]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell activation [GO:0042110]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to cytokine stimulus [GO:0071345]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; death-inducing signaling complex assembly [GO:0071550]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macrophage differentiation [GO:0030225]; natural killer cell activation [GO:0030101]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of proteolysis [GO:0045862]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of necroptotic process [GO:0060544]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039650]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell activation [GO:0042110]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; IPAF inflammasome complex [GO:0072557]; NLRP1 inflammasome complex [GO:0072558]; NLRP3 inflammasome complex [GO:0072559]; plasma membrane [GO:0005886]; protease inhibitor complex [GO:0097179]; protein-containing complex [GO:0032991]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ripoptosome [GO:0097342]	CARD domain binding [GO:0050700]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]	cysteine-type endopeptidase activity [GO:0004197]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097199]; cysteine-type peptidase activity [GO:0008234]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]
d1rwqb2_d3stta___1	Metazoa	Viridiplantae	Chordata	Streptophyta	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d1rwyb__d2ggza___1	Metazoa	Metazoa	Chordata	Chordata	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cochlea development [GO:0090102]	photoreceptor disc membrane [GO:0097381]; calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; signal transduction [GO:0007165]; visual perception [GO:0007601]	cochlea development [GO:0090102]	regulation of rhodopsin mediated signaling pathway [GO:0022400]; signal transduction [GO:0007165]; visual perception [GO:0007601]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]	photoreceptor disc membrane [GO:0097381]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048]
d1rwza1_d6amsd2__1			Euryarchaeota	Proteobacteria	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA strand elongation involved in DNA replication [GO:0006271]		cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1rx0a1_d3swoa2__1	Metazoa		Chordata	Actinobacteria	mitochondrial matrix [GO:0005759]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; branched-chain amino acid catabolic process [GO:0009083]; lipid metabolic process [GO:0006629]; valine catabolic process [GO:0006574]	flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA hydrolase activity [GO:0044466]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	branched-chain amino acid catabolic process [GO:0009083]; lipid metabolic process [GO:0006629]; valine catabolic process [GO:0006574]		mitochondrial matrix [GO:0005759]		acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA hydrolase activity [GO:0044466]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d1rx0c1_d1eged1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; branched-chain amino acid catabolic process [GO:0009083]; lipid metabolic process [GO:0006629]; valine catabolic process [GO:0006574]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	branched-chain amino acid catabolic process [GO:0009083]; lipid metabolic process [GO:0006629]; valine catabolic process [GO:0006574]	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	mitochondrial matrix [GO:0005759]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]
d1rx2a__d4ddra___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1rx3a__d4elge1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1rx5a__d3jw5b1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1rx7a__d1ohja___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1rxcd__d3enza1__1			Proteobacteria	Apicomplexa	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	purine-nucleoside phosphorylase activity [GO:0004731]
d1rxce__d1odie___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	transferase activity, transferring pentosyl groups [GO:0016763]; nucleoside metabolic process [GO:0009116]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	transferase activity, transferring pentosyl groups [GO:0016763]
d1rxce__d3nbqa___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uridine phosphorylase activity [GO:0004850]; cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	uridine phosphorylase activity [GO:0004850]
d1rxcj__d4bmza___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]; 6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	cytosol [GO:0005829]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d1rxha__d1lcva___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1rxia__d4etmb1__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]	protein tyrosine phosphatase activity [GO:0004725]	response to arsenic-containing substance [GO:0046685]		cytoplasm [GO:0005737]		arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d1rxkb__d3szii___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1rxma1_d1dmlc1__1			Euryarchaeota		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	host cell nucleus [GO:0042025]; DNA binding [GO:0003677]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]		host cell nucleus [GO:0042025]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	DNA binding [GO:0003677]
d1rxma2_d3f1vb3__1			Euryarchaeota	Proteobacteria	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1rxta2_d4kota___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]; cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]	cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]
d1rxtd2_d4m85a1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]; cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	N-acetyltransferase activity [GO:0008080]	cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]	N-acetyltransferase activity [GO:0008080]
d1rxua__d1pk7b___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	purine nucleoside metabolic process [GO:0042278]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	purine-nucleoside phosphorylase activity [GO:0004731]
d1rxua__d2p4sc___1		Metazoa	Proteobacteria	Arthropoda	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytoplasm [GO:0005737]; purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	purine-nucleoside phosphorylase activity [GO:0004731]
d1rxuc__d2h8gb___1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cytosol [GO:0005829]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d1rxui__d1ovga___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]
d1rxul__d4wkpc1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d1rxum__d3lgsc___1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cytosol [GO:0005829]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d1rxur__d1k3fc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]
d1rxya__d5mx6a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	purine nucleoside metabolic process [GO:0042278]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	purine-nucleoside phosphorylase activity [GO:0004731]
d1rxza2_d3f1va3__1			Euryarchaeota	Proteobacteria	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1rxza2_d3tblb1__1		Metazoa	Euryarchaeota	Chordata	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d1ry0b__d5jgwa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]; 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; prostaglandin-F synthase activity [GO:0047017]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]		15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin-F synthase activity [GO:0047017]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1ry7b1_d3lrsl2__1	Metazoa		Chordata		cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]		activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]		cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]		fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	
d1ry9a__d1n5ba___1			Proteobacteria	Proteobacteria	pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; pathogenesis [GO:0009405]; regulation of protein secretion [GO:0050708]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]; regulation of protein secretion [GO:0050708]		cytoplasm [GO:0005737]		
d1ry9d__d4jmfc___1			Proteobacteria	Proteobacteria	pathogenesis [GO:0009405]	extracellular region [GO:0005576]; GTPase activator activity [GO:0005096]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]		GTPase activator activity [GO:0005096]
d1ryaa__d1nfzb1__1			Proteobacteria	Proteobacteria	GDP-glucosidase activity [GO:0047917]; GDP-mannose mannosyl hydrolase activity [GO:0008727]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; lipopolysaccharide biosynthetic process [GO:0009103]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	lipopolysaccharide biosynthetic process [GO:0009103]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]		cytoplasm [GO:0005737]	GDP-glucosidase activity [GO:0047917]; GDP-mannose mannosyl hydrolase activity [GO:0008727]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]
d1ryaa__d2gt4a___1			Proteobacteria	Proteobacteria	GDP-glucosidase activity [GO:0047917]; GDP-mannose mannosyl hydrolase activity [GO:0008727]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; lipopolysaccharide biosynthetic process [GO:0009103]	GDP-glucosidase activity [GO:0047917]; GDP-mannose mannosyl hydrolase activity [GO:0008727]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]			GDP-glucosidase activity [GO:0047917]; GDP-mannose mannosyl hydrolase activity [GO:0008727]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]	GDP-glucosidase activity [GO:0047917]; GDP-mannose mannosyl hydrolase activity [GO:0008727]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]
d1ryca__d1eqga1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1ryic2_d2h94a3__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]; cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	DNA repair complex [GO:1990391]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; androgen receptor binding [GO:0050681]; chromatin binding [GO:0003682]; demethylase activity [GO:0032451]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-dimethyl-K4 specific) [GO:0034648]; histone demethylase activity (H3-K4 specific) [GO:0032453]; histone demethylase activity (H3-K9 specific) [GO:0032454]; MRF binding [GO:0043426]; nuclear receptor transcription coactivator activity [GO:0030374]; oxidoreductase activity [GO:0016491]; p53 binding [GO:0002039]; RNA polymerase II transcription factor binding [GO:0001085]; telomeric DNA binding [GO:0042162]; telomeric repeat-containing RNA binding [GO:0061752]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; alternative mRNA splicing, via spliceosome [GO:0000380]; blood coagulation [GO:0007596]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; histone H3-K9 demethylation [GO:0033169]; muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron maturation [GO:0042551]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of histone ubiquitination [GO:0033184]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of cellular protein localization [GO:1903827]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fungicide [GO:0060992]	cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	alternative mRNA splicing, via spliceosome [GO:0000380]; blood coagulation [GO:0007596]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; histone H3-K9 demethylation [GO:0033169]; muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron maturation [GO:0042551]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of histone ubiquitination [GO:0033184]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of cellular protein localization [GO:1903827]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fungicide [GO:0060992]	cytoplasm [GO:0005737]	DNA repair complex [GO:1990391]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]	FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]	androgen receptor binding [GO:0050681]; chromatin binding [GO:0003682]; demethylase activity [GO:0032451]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-dimethyl-K4 specific) [GO:0034648]; histone demethylase activity (H3-K4 specific) [GO:0032453]; histone demethylase activity (H3-K9 specific) [GO:0032454]; MRF binding [GO:0043426]; nuclear receptor transcription coactivator activity [GO:0030374]; oxidoreductase activity [GO:0016491]; p53 binding [GO:0002039]; RNA polymerase II transcription factor binding [GO:0001085]; telomeric DNA binding [GO:0042162]; telomeric repeat-containing RNA binding [GO:0061752]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1ryoa__d1h76a2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cell [GO:0005623]; extracellular space [GO:0005615]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; cellular iron ion homeostasis [GO:0006879]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cellular iron ion homeostasis [GO:0006879]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell [GO:0005623]; extracellular space [GO:0005615]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]
d1ryp2__d1pmav___1	Fungi		Ascomycota	Euryarchaeota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1rypd__d4qwgo___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1rypf__d3nzwt___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1rypf__d4inti___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ryph__d4lqie___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1rypl__d4qv1f___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1rypl__d4qv8q___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ryps__d5l5ho___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ryyb1_d1ju3a1__1			Proteobacteria	Actinobacteria	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]		cocaine catabolic process [GO:0050784]		cytoplasm [GO:0005737]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]
d1ryyb1_d2g9fa1__1		Metazoa	Proteobacteria	Chordata	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]; glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	metal ion binding [GO:0046872]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]
d1ryyc1_d1ju4a1__1			Proteobacteria	Actinobacteria	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]		cocaine catabolic process [GO:0050784]		cytoplasm [GO:0005737]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]
d1ryyd1_d3ogva5__1		Fungi	Proteobacteria	Ascomycota	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	beta-galactosidase activity [GO:0004565]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	beta-galactosidase activity [GO:0004565]
d1ryye1_d3t2qc1__1			Proteobacteria	Proteobacteria	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1ryyh1_d1lnsa2__1			Proteobacteria	Firmicutes	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	cytoplasm [GO:0005737]; dipeptidyl-peptidase activity [GO:0008239]; serine-type peptidase activity [GO:0008236]				cytoplasm [GO:0005737]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	dipeptidyl-peptidase activity [GO:0008239]; serine-type peptidase activity [GO:0008236]
d1ryzd__d1rxcl___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	uridine phosphorylase activity [GO:0004850]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]
d1ryze__d5m2tb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	uridine phosphorylase activity [GO:0004850]	metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]
d1ryzf__d3euea___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uridine phosphorylase activity [GO:0004850]; cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	uridine phosphorylase activity [GO:0004850]	uridine phosphorylase activity [GO:0004850]
d1rz8a2_d3mrob1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rz8a2_d5esab2__1												
d1rz8b1_d1il1a2__1												
d1rz8b1_d2nxyb1__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1rz8b2_d1qvob1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rz8c1_d1s9yb1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rz8c2_d4pp2a1__1		Metazoa		Arthropoda		extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]				extracellular region [GO:0005576]		cysteine-type peptidase activity [GO:0008234]
d1rz8d1_d1mhpy___1		Metazoa		Chordata		acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]		activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]		acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]		collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]
d1rz8d1_d3u9pl1__1		Metazoa		Chordata		cell [GO:0005623]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to bacterium [GO:0009617]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]		cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to bacterium [GO:0009617]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]		cell [GO:0005623]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1rz8d2_d3tnnd1__1												
d1rzfl1_d4uuja2__1				Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1rzga2_d5d5mh2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rzgd1_d5f7kd1__1				Proteobacteria								
d1rzie1_d4lfhd2__1		Metazoa		Chordata								
d1rzif2_d3vwkd1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rzii1_d1yyll2__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1rzii2_d5anma2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1rzij2_d4m48l1__1		Metazoa		Arthropoda		integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]; adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]		adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]		integral component of plasma membrane [GO:0005887]; neuronal cell body membrane [GO:0032809]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]		cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]
d1rzik2_d4dgil1__1		Metazoa		Chordata		anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d1rzil2_d1s7xb___1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rzim1_d2i9lc1__1						integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		
d1rzim2_d2gj6d2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rzim2_d5lhnb1__1		Metazoa		Chordata		cell surface [GO:0009986]; extracellular space [GO:0005615]; membrane [GO:0016020]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; angiogenesis [GO:0001525]; fibrinolysis [GO:0042730]; neuron death [GO:0070997]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ovulation [GO:0060279]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell migration [GO:0014911]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of hepatocyte proliferation [GO:2000345]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; response to hypoxia [GO:0001666]; skeletal muscle tissue regeneration [GO:0043403]; smooth muscle cell migration [GO:0014909]; wound healing [GO:0042060]		angiogenesis [GO:0001525]; fibrinolysis [GO:0042730]; neuron death [GO:0070997]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ovulation [GO:0060279]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell migration [GO:0014911]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of hepatocyte proliferation [GO:2000345]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; response to hypoxia [GO:0001666]; skeletal muscle tissue regeneration [GO:0043403]; smooth muscle cell migration [GO:0014909]; wound healing [GO:0042060]		cell surface [GO:0009986]; extracellular space [GO:0005615]; membrane [GO:0016020]		peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]
d1rzin2_d1j05h___1		Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		
d1rzin2_d3ft2b1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rzio1_d3agvb1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1rzio2_d4kkld2__1				Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1rzip2_d2z91d1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1rzjc2_d2bckd1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rzjh2_d5u17e2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1rzjl2_d1b0wa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d1rzkc1_d4d9rd1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1rzkh1_d2xzcl1__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1rzkl2_d4hfwa1__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1rzma__d1zaja___1		Metazoa	Thermotogae	Chordata	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]		I band [GO:0031674]; M band [GO:0031430]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]	fructose-bisphosphate aldolase activity [GO:0004332]
d1rzmb__d3pb2a1__1			Thermotogae	Thermotogae	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1rzob1_d3o5wb1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1rzoc__d5u4ma___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]	endoplasmic reticulum [GO:0005783]	carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1rzpa1_d1jvoe___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1rzpa2_d1j9qa2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1rzpa2_d4knsb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1rzpb1_d1ws8d___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1rzpc1_d5d4ib1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1rzpc2_d4mfha___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1rzqa1_d2fjsa1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1rzqb1_d3np4a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1rzqb2_d2azuc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1rzqc2_d5a7ea1__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1rzte3_d4k8vc1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immune response [GO:0050776]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]; regulation of type I interferon production [GO:0032479]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immune response [GO:0050776]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]; regulation of type I interferon production [GO:0032479]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]
d1rzti1_d8icaa1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d1rzti3_d5dedf___1	Metazoa		Chordata	Firmicutes	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; GTP diphosphokinase activity [GO:0008728]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; guanosine tetraphosphate biosynthetic process [GO:0015970]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	guanosine tetraphosphate biosynthetic process [GO:0015970]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]		5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; GTP diphosphokinase activity [GO:0008728]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]
d1rzwa1_d2zv3b___1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	aminoacyl-tRNA hydrolase activity [GO:0004045]	aminoacyl-tRNA hydrolase activity [GO:0004045]
d1s05a__d1gqaa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1s05a__d4u9dc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1s07b__d3k7ya___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]	biotin biosynthetic process [GO:0009102]	biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]		adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]	L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1s0ca3_d1fjwa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1s0da2_d5fzua___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	endopeptidase inhibitor activity [GO:0004866]; peptidase activity [GO:0008233]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]		lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	endopeptidase inhibitor activity [GO:0004866]; peptidase activity [GO:0008233]
d1s0ea1_d1d0ha1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1s0ea2_d3r4sa2__1			Firmicutes		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; ganglioside binding [GO:0035594]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; membrane protein proteolysis [GO:0033619]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	membrane protein proteolysis [GO:0033619]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	ganglioside binding [GO:0035594]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1s0fa1_d1olra___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	negative regulation of neurotransmitter secretion [GO:0046929]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]		lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	cellulase activity [GO:0008810]
d1s0fa3_d1thla___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1s0ga2_d1diwa2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1s0ga2_d5fnxa___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	endopeptidase inhibitor activity [GO:0004866]; peptidase activity [GO:0008233]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]		lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	endopeptidase inhibitor activity [GO:0004866]; peptidase activity [GO:0008233]
d1s0la__d1z2vb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1s0ob1_d3ohaa2__1		Fungi	Crenarchaeota	Ascomycota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d1s0qa__d5gsod___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cysteine-type endopeptidase activity [GO:0004197]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]
d1s12b__d2g0jd2__1			Thermotogae	Firmicutes								
d1s16b1_d1ei1a1__1			Proteobacteria	Proteobacteria	chromosome [GO:0005694]; cytosol [GO:0005829]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; chromosome organization [GO:0051276]; DNA topological change [GO:0006265]; plasmid partitioning [GO:0030541]; response to antibiotic [GO:0046677]; sister chromatid cohesion [GO:0007062]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; DNA-dependent ATPase activity [GO:0008094]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	chromosome organization [GO:0051276]; DNA topological change [GO:0006265]; plasmid partitioning [GO:0030541]; response to antibiotic [GO:0046677]; sister chromatid cohesion [GO:0007062]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	chromosome [GO:0005694]; cytosol [GO:0005829]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d1s16b1_d2qbfe1__1			Proteobacteria		chromosome [GO:0005694]; cytosol [GO:0005829]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; chromosome organization [GO:0051276]; DNA topological change [GO:0006265]; plasmid partitioning [GO:0030541]; response to antibiotic [GO:0046677]; sister chromatid cohesion [GO:0007062]		chromosome organization [GO:0051276]; DNA topological change [GO:0006265]; plasmid partitioning [GO:0030541]; response to antibiotic [GO:0046677]; sister chromatid cohesion [GO:0007062]		chromosome [GO:0005694]; cytosol [GO:0005829]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]	
d1s16b2_d5lo0a___1		Metazoa	Proteobacteria	Chordata	chromosome [GO:0005694]; cytosol [GO:0005829]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; chromosome organization [GO:0051276]; DNA topological change [GO:0006265]; plasmid partitioning [GO:0030541]; response to antibiotic [GO:0046677]; sister chromatid cohesion [GO:0007062]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	chromosome organization [GO:0051276]; DNA topological change [GO:0006265]; plasmid partitioning [GO:0030541]; response to antibiotic [GO:0046677]; sister chromatid cohesion [GO:0007062]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	chromosome [GO:0005694]; cytosol [GO:0005829]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1s1aa__d1dy4a___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d1s1ab__d1qh7a___1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d1s1db__d2h2ua___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; adenosine-diphosphatase activity [GO:0043262]; calcium ion binding [GO:0005509]; guanosine-diphosphatase activity [GO:0004382]; protein homodimerization activity [GO:0042803]; uridine-diphosphatase activity [GO:0045134]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; proteoglycan biosynthetic process [GO:0030166]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; adenosine-diphosphatase activity [GO:0043262]; calcium ion binding [GO:0005509]; guanosine-diphosphatase activity [GO:0004382]; protein homodimerization activity [GO:0042803]; uridine-diphosphatase activity [GO:0045134]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; proteoglycan biosynthetic process [GO:0030166]	neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; proteoglycan biosynthetic process [GO:0030166]	neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; proteoglycan biosynthetic process [GO:0030166]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	adenosine-diphosphatase activity [GO:0043262]; calcium ion binding [GO:0005509]; guanosine-diphosphatase activity [GO:0004382]; protein homodimerization activity [GO:0042803]; uridine-diphosphatase activity [GO:0045134]	adenosine-diphosphatase activity [GO:0043262]; calcium ion binding [GO:0005509]; guanosine-diphosphatase activity [GO:0004382]; protein homodimerization activity [GO:0042803]; uridine-diphosphatase activity [GO:0045134]
d1s1ea1_d2m7ma___1	Metazoa		Chordata		cytoplasm [GO:0005737]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]; calcium ion binding [GO:0005509]; potassium channel activity [GO:0005267]; potassium channel regulator activity [GO:0015459]; voltage-gated ion channel activity [GO:0005244]; cardiac conduction [GO:0061337]; regulation of potassium ion transmembrane transport [GO:1901379]	calcium ion binding [GO:0005509]	cardiac conduction [GO:0061337]; regulation of potassium ion transmembrane transport [GO:1901379]		cytoplasm [GO:0005737]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]		calcium ion binding [GO:0005509]; potassium channel activity [GO:0005267]; potassium channel regulator activity [GO:0015459]; voltage-gated ion channel activity [GO:0005244]	calcium ion binding [GO:0005509]
d1s1pa__d2r9ra___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]; 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; prostaglandin-F synthase activity [GO:0047017]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin-F synthase activity [GO:0047017]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]
d1s1va1_d3ey1a___1				Firmicutes	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1s1ya__d3c2wh3__1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d1s26d__d1avsb___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	troponin complex [GO:0005861]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]
d1s26e__d1g4yr___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; small conductance calcium-activated potassium channel activity [GO:0016286]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of neuronal synaptic plasticity [GO:0048168]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of neuronal synaptic plasticity [GO:0048168]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calmodulin binding [GO:0005516]; small conductance calcium-activated potassium channel activity [GO:0016286]
d1s26f__d2lmua___1	Metazoa	Metazoa	Chordata	Arthropoda	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; investment cone [GO:0070865]; myosin VI complex [GO:0031476]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; myosin VI head/neck binding [GO:0070855]; actin filament-based movement [GO:0030048]; calcium-mediated signaling [GO:0019722]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	actin filament-based movement [GO:0030048]; calcium-mediated signaling [GO:0019722]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; investment cone [GO:0070865]; myosin VI complex [GO:0031476]; nucleus [GO:0005634]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]; myosin VI head/neck binding [GO:0070855]
d1s2gc__d3ropa___1		Metazoa	Firmicutes	Chordata	nucleoside deoxyribosyltransferase activity [GO:0050144]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]		apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]		basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	nucleoside deoxyribosyltransferase activity [GO:0050144]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d1s2lb__d2i66b___1		Metazoa	Firmicutes	Chordata	nucleoside deoxyribosyltransferase activity [GO:0050144]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]		apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]		basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	nucleoside deoxyribosyltransferase activity [GO:0050144]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d1s2qb2_d3cphh3__1	Metazoa	Fungi	Chordata	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]
d1s2ta__d5dqld___1	Metazoa		Mollusca	Actinobacteria	metal ion binding [GO:0046872]; phosphoenolpyruvate mutase activity [GO:0050188]; organic phosphonate biosynthetic process [GO:0032923]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]; zymogen binding [GO:0035375]; cellular response to hypoxia [GO:0071456]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; maintenance of symbiont tolerance to host environment [GO:0075141]; pathogenesis [GO:0009405]; response to acetate [GO:0010034]; response to acidic pH [GO:0010447]; response to fatty acid [GO:0070542]; response to host immune response [GO:0052572]; tricarboxylic acid cycle [GO:0006099]	organic phosphonate biosynthetic process [GO:0032923]	cellular response to hypoxia [GO:0071456]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; maintenance of symbiont tolerance to host environment [GO:0075141]; pathogenesis [GO:0009405]; response to acetate [GO:0010034]; response to acidic pH [GO:0010447]; response to fatty acid [GO:0070542]; response to host immune response [GO:0052572]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; phosphoenolpyruvate mutase activity [GO:0050188]	isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]; zymogen binding [GO:0035375]
d1s2ub__d1f61b___1	Metazoa		Mollusca	Actinobacteria	metal ion binding [GO:0046872]; phosphoenolpyruvate mutase activity [GO:0050188]; organic phosphonate biosynthetic process [GO:0032923]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]; zymogen binding [GO:0035375]; cellular response to hypoxia [GO:0071456]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; maintenance of symbiont tolerance to host environment [GO:0075141]; pathogenesis [GO:0009405]; response to acetate [GO:0010034]; response to acidic pH [GO:0010447]; response to fatty acid [GO:0070542]; response to host immune response [GO:0052572]; tricarboxylic acid cycle [GO:0006099]	organic phosphonate biosynthetic process [GO:0032923]	cellular response to hypoxia [GO:0071456]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; maintenance of symbiont tolerance to host environment [GO:0075141]; pathogenesis [GO:0009405]; response to acetate [GO:0010034]; response to acidic pH [GO:0010447]; response to fatty acid [GO:0070542]; response to host immune response [GO:0052572]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; phosphoenolpyruvate mutase activity [GO:0050188]	isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]; zymogen binding [GO:0035375]
d1s2yb2_d1el8b2__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	tetrahydrofolate metabolic process [GO:0046653]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	sarcosine oxidase activity [GO:0008115]
d1s30a1_d5ls9d___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]	cell [GO:0005623]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]
d1s32a__d5gsuh___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1s32e__d5ay8d___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1s35a1_d1hcia2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell surface [GO:0009986]; cytosol [GO:0005829]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; protein-containing complex [GO:0032991]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; ankyrin binding [GO:0030506]; structural constituent of cytoskeleton [GO:0005200]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; pseudopodium [GO:0031143]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]; actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]	actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin cytoskeleton [GO:0015629]; cell surface [GO:0009986]; cytosol [GO:0005829]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; protein-containing complex [GO:0032991]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; pseudopodium [GO:0031143]; Z disc [GO:0030018]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; ankyrin binding [GO:0030506]; structural constituent of cytoskeleton [GO:0005200]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]
d1s35a2_d1aj3a___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell surface [GO:0009986]; cytosol [GO:0005829]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; protein-containing complex [GO:0032991]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; ankyrin binding [GO:0030506]; structural constituent of cytoskeleton [GO:0005200]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; actin filament capping [GO:0051693]	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]	actin filament capping [GO:0051693]	actin cytoskeleton [GO:0015629]; cell surface [GO:0009986]; cytosol [GO:0005829]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; protein-containing complex [GO:0032991]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; ankyrin binding [GO:0030506]; structural constituent of cytoskeleton [GO:0005200]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]
d1s3bb2_d1vg9a2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; Rab-protein geranylgeranyltransferase complex [GO:0005968]; GDP-dissociation inhibitor activity [GO:0005092]; GTPase activator activity [GO:0005096]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; protein geranylgeranylation [GO:0018344]; protein targeting to membrane [GO:0006612]; protein-containing complex assembly [GO:0065003]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	protein-containing complex assembly [GO:0065003]; protein geranylgeranylation [GO:0018344]; protein targeting to membrane [GO:0006612]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; Rab-protein geranylgeranyltransferase complex [GO:0005968]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	GDP-dissociation inhibitor activity [GO:0005092]; GTPase activator activity [GO:0005096]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]
d1s3eb2_d1c0ka2__1	Metazoa	Fungi	Chordata	Basidiomycota	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	peroxisome [GO:0005777]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; D-amino acid metabolic process [GO:0046416]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-amino acid metabolic process [GO:0046416]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	peroxisome [GO:0005777]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]
d1s3kh1_d4f7cd___1		Metazoa		Chordata		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]		
d1s3la__d1ii7b___1			Euryarchaeota	Euryarchaeota	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]; double-strand break repair [GO:0006302]		double-strand break repair [GO:0006302]			hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]
d1s3ma__d3psna1__1		Metazoa	Euryarchaeota	Chordata	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer complex [GO:0030904]; retromer, cargo-selective complex [GO:0030906]; metal ion binding [GO:0046872]; endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]		endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]		cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer, cargo-selective complex [GO:0030906]; retromer complex [GO:0030904]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1s3nb__d1t70d___1			Euryarchaeota	Deinococcus-Thermus	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]; phosphoenolpyruvate phosphatase activity [GO:0050189]					hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]; phosphoenolpyruvate phosphatase activity [GO:0050189]
d1s3pa__d1br1h___1	Metazoa	Metazoa	Chordata	Chordata	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cochlea development [GO:0090102]	muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin filament [GO:0032982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin-dependent ATPase activity [GO:0030898]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; magnesium ion binding [GO:0000287]; microfilament motor activity [GO:0000146]; myosin II binding [GO:0045159]; myosin light chain binding [GO:0032027]; protein heterodimerization activity [GO:0046982]; structural constituent of muscle [GO:0008307]; cardiac muscle fiber development [GO:0048739]; elastic fiber assembly [GO:0048251]; myofibril assembly [GO:0030239]; skeletal muscle myosin thick filament assembly [GO:0030241]; smooth muscle contraction [GO:0006939]	cochlea development [GO:0090102]	cardiac muscle fiber development [GO:0048739]; elastic fiber assembly [GO:0048251]; myofibril assembly [GO:0030239]; skeletal muscle myosin thick filament assembly [GO:0030241]; smooth muscle contraction [GO:0006939]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]	muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin filament [GO:0032982]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; actin-dependent ATPase activity [GO:0030898]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; magnesium ion binding [GO:0000287]; microfilament motor activity [GO:0000146]; myosin II binding [GO:0045159]; myosin light chain binding [GO:0032027]; protein heterodimerization activity [GO:0046982]; structural constituent of muscle [GO:0008307]
d1s3sc3_d3hu2b2__1	Metazoa	Metazoa	Chordata	Chordata	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1s3se2_d4mitc___1	Metazoa		Chordata		ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; small GTPase mediated signal transduction [GO:0007264]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	small GTPase mediated signal transduction [GO:0007264]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	plasma membrane [GO:0005886]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1s3sf2_d1ny6m___1	Metazoa		Chordata	Aquificae	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d1s3sf2_d2g1ka___1	Metazoa		Chordata	Actinobacteria	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	cytosol [GO:0005829]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]
d1s3sf3_d4kodb2__1	Metazoa	Metazoa	Chordata	Chordata	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1s44a__d2rq0a1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular space [GO:0005615]; pigment binding [GO:0031409]; protein-chromophore linkage [GO:0018298]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; response to glucocorticoid [GO:0051384]	protein-chromophore linkage [GO:0018298]	negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; response to glucocorticoid [GO:0051384]	extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	pigment binding [GO:0031409]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d1s46a1_d1vfoa2__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		amylosucrase activity [GO:0047669]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1s46a2_d1uaha___1			Proteobacteria		extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		amylosucrase activity [GO:0047669]	
d1s4bp__d4h82c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; peptide binding [GO:0042277]; peptide metabolic process [GO:0006518]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	peptide metabolic process [GO:0006518]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; peptide binding [GO:0042277]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1s4cb__d5plva___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]		cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	cytosol [GO:0005829]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]		chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d1s4mb2_d3x1jb___1			Thermotogae	Proteobacteria	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]; FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; [citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]	[citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1s4sa__d1otda___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d1s4va__d3d9wc___1	Viridiplantae		Streptophyta	Actinobacteria	cytoplasmic vesicle [GO:0031410]; cysteine-type peptidase activity [GO:0008234]	acetyltransferase activity [GO:0016407]			cytoplasmic vesicle [GO:0031410]		cysteine-type peptidase activity [GO:0008234]	acetyltransferase activity [GO:0016407]
d1s4vb__d1f29b___1	Viridiplantae		Streptophyta		cytoplasmic vesicle [GO:0031410]; cysteine-type peptidase activity [GO:0008234]	cysteine-type endopeptidase activity [GO:0004197]			cytoplasmic vesicle [GO:0031410]		cysteine-type peptidase activity [GO:0008234]	cysteine-type endopeptidase activity [GO:0004197]
d1s55b__d4qqlg___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of JUN kinase activity [GO:0007257]; animal organ morphogenesis [GO:0009887]; bone development [GO:0060348]; bone resorption [GO:0045453]; calcium ion homeostasis [GO:0055074]; calcium-mediated signaling [GO:0019722]; cellular response to leukemia inhibitory factor [GO:1990830]; cytokine-mediated signaling pathway [GO:0019221]; ERK1 and ERK2 cascade [GO:0070371]; immune response [GO:0006955]; lymph node development [GO:0048535]; mammary gland alveolus development [GO:0060749]; mammary gland epithelial cell proliferation [GO:0033598]; monocyte chemotaxis [GO:0002548]; ossification [GO:0001503]; osteoclast development [GO:0036035]; osteoclast differentiation [GO:0030316]; osteoclast proliferation [GO:0002158]; paracrine signaling [GO:0038001]; positive regulation of bone resorption [GO:0045780]; positive regulation of corticotropin-releasing hormone secretion [GO:0051466]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling [GO:0071848]; positive regulation of fever generation by positive regulation of prostaglandin secretion [GO:0071812]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoclast development [GO:2001206]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin binding [GO:1904616]; regulation of osteoclast differentiation [GO:0045670]; TNFSF11-mediated signaling pathway [GO:0071847]; tooth eruption [GO:0044691]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	collagen trimer [GO:0005581]; extracellular region [GO:0005576]; identical protein binding [GO:0042802]; regulation of synapse organization [GO:0050807]	activation of JUN kinase activity [GO:0007257]; animal organ morphogenesis [GO:0009887]; bone development [GO:0060348]; bone resorption [GO:0045453]; calcium ion homeostasis [GO:0055074]; calcium-mediated signaling [GO:0019722]; cellular response to leukemia inhibitory factor [GO:1990830]; cytokine-mediated signaling pathway [GO:0019221]; ERK1 and ERK2 cascade [GO:0070371]; immune response [GO:0006955]; lymph node development [GO:0048535]; mammary gland alveolus development [GO:0060749]; mammary gland epithelial cell proliferation [GO:0033598]; monocyte chemotaxis [GO:0002548]; ossification [GO:0001503]; osteoclast development [GO:0036035]; osteoclast differentiation [GO:0030316]; osteoclast proliferation [GO:0002158]; paracrine signaling [GO:0038001]; positive regulation of bone resorption [GO:0045780]; positive regulation of corticotropin-releasing hormone secretion [GO:0051466]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling [GO:0071848]; positive regulation of fever generation by positive regulation of prostaglandin secretion [GO:0071812]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoclast development [GO:2001206]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin binding [GO:1904616]; regulation of osteoclast differentiation [GO:0045670]; TNFSF11-mediated signaling pathway [GO:0071847]; tooth eruption [GO:0044691]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	regulation of synapse organization [GO:0050807]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	collagen trimer [GO:0005581]; extracellular region [GO:0005576]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	identical protein binding [GO:0042802]
d1s56a__d1xy0c___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1s57b__d3fkbd___1	Viridiplantae		Streptophyta		chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1s57d__d1vyab___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]	nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]
d1s59d__d1f6tc___1	Viridiplantae		Streptophyta		chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1s59f__d1ucnc___1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]; cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]
d1s59f__d5yold___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1s5dd__d1fnwb1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1s5dd__d2xrso___1			Proteobacteria	Proteobacteria	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1s5dg__d4rh6c1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	pathogenesis [GO:0009405]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]	
d1s5eg__d3r2ia1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	pathogenesis [GO:0009405]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]	
d1s5ek__d1bosq___1			Proteobacteria		catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1s5en__d1pzih___1			Proteobacteria	Proteobacteria	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1s5en__d1ts3b1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	pathogenesis [GO:0009405]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1s5fd__d4o1nc1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; peptidase activity [GO:0008233]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	pathogenesis [GO:0009405]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]	peptidase activity [GO:0008233]
d1s5fe__d1eefm___1			Proteobacteria	Proteobacteria	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1s5fe__d1v1pb1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	pathogenesis [GO:0009405]	catalytic complex [GO:1902494]; extracellular space [GO:0005615]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; toxin activity [GO:0090729]	
d1s5ha2_d1ap2b___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1s5hb1_d4rdql1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]; chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1s5hb2_d1l0xc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1s5ih2_d5jqdb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1s5il1_d4m5ym2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1s5ma__d9ximb___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1s5oa1_d3u9fp___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; protein targeting to peroxisome [GO:0006625]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; protein targeting to peroxisome [GO:0006625]	response to antibiotic [GO:0046677]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		carnitine O-acetyltransferase activity [GO:0004092]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d1s5oa2_d1q23c___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; protein targeting to peroxisome [GO:0006625]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; protein targeting to peroxisome [GO:0006625]	response to antibiotic [GO:0046677]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		carnitine O-acetyltransferase activity [GO:0004092]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d1s5qb__d2f05a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; chromatin [GO:0000785]; kinetochore [GO:0000776]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; Sin3 complex [GO:0016580]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein deacetylase activity [GO:0033558]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II repressing transcription factor binding [GO:0001103]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular protein localization [GO:0034613]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; cerebral cortex neuron differentiation [GO:0021895]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of histone H3-K27 acetylation [GO:1901675]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; regulation of axon extension [GO:0030516]; regulation of hormone levels [GO:0010817]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; regulation of transcription, DNA-templated [GO:0006355]; response to methylglyoxal [GO:0051595]; response to organonitrogen compound [GO:0010243]; rhythmic process [GO:0048511]	autosome [GO:0030849]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; Sin3 complex [GO:0016580]; X chromosome [GO:0000805]; XY body [GO:0001741]; Y chromosome [GO:0000806]; chromatin binding [GO:0003682]; transcription corepressor activity [GO:0003714]; cardiac muscle tissue development [GO:0048738]; histone deacetylation [GO:0016575]; negative regulation of cell cycle [GO:0045786]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; skeletal muscle tissue development [GO:0007519]	activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular protein localization [GO:0034613]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; cerebral cortex neuron differentiation [GO:0021895]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of histone H3-K27 acetylation [GO:1901675]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; regulation of axon extension [GO:0030516]; regulation of hormone levels [GO:0010817]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to methylglyoxal [GO:0051595]; response to organonitrogen compound [GO:0010243]; rhythmic process [GO:0048511]	cardiac muscle tissue development [GO:0048738]; histone deacetylation [GO:0016575]; negative regulation of cell cycle [GO:0045786]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; skeletal muscle tissue development [GO:0007519]	cell [GO:0005623]; chromatin [GO:0000785]; kinetochore [GO:0000776]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; Sin3 complex [GO:0016580]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	autosome [GO:0030849]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; Sin3 complex [GO:0016580]; X chromosome [GO:0000805]; XY body [GO:0001741]; Y chromosome [GO:0000806]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein-containing complex binding [GO:0044877]; protein deacetylase activity [GO:0033558]; RNA binding [GO:0003723]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II repressing transcription factor binding [GO:0001103]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	chromatin binding [GO:0003682]; transcription corepressor activity [GO:0003714]
d1s5rb__d1pd7a___1	Metazoa	Metazoa	Chordata	Chordata	nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; negative regulation of lipid transport [GO:0032369]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of potassium ion transport [GO:0043268]; Wnt signaling pathway [GO:0016055]	autosome [GO:0030849]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; Sin3 complex [GO:0016580]; X chromosome [GO:0000805]; XY body [GO:0001741]; Y chromosome [GO:0000806]; chromatin binding [GO:0003682]; transcription corepressor activity [GO:0003714]; cardiac muscle tissue development [GO:0048738]; histone deacetylation [GO:0016575]; negative regulation of cell cycle [GO:0045786]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; skeletal muscle tissue development [GO:0007519]	negative regulation of lipid transport [GO:0032369]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of potassium ion transport [GO:0043268]; Wnt signaling pathway [GO:0016055]	cardiac muscle tissue development [GO:0048738]; histone deacetylation [GO:0016575]; negative regulation of cell cycle [GO:0045786]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; skeletal muscle tissue development [GO:0007519]	nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	autosome [GO:0030849]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; Sin3 complex [GO:0016580]; X chromosome [GO:0000805]; XY body [GO:0001741]; Y chromosome [GO:0000806]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]	chromatin binding [GO:0003682]; transcription corepressor activity [GO:0003714]
d1s5tb__d1rvgc___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	fructose-bisphosphate aldolase activity [GO:0004332]; zinc ion binding [GO:0008270]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; glycolytic process [GO:0006096]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	fructose 1,6-bisphosphate metabolic process [GO:0030388]; glycolytic process [GO:0006096]	cytosol [GO:0005829]		4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]	fructose-bisphosphate aldolase activity [GO:0004332]; zinc ion binding [GO:0008270]
d1s5ue1_d2fuja1__1			Proteobacteria	Proteobacteria	plasma membrane [GO:0005886]; acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]; lipid metabolic process [GO:0006629]	acyl-CoA hydrolase activity [GO:0047617]	lipid metabolic process [GO:0006629]		plasma membrane [GO:0005886]		acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]	acyl-CoA hydrolase activity [GO:0047617]
d1s5uf__d3r3ca___1			Proteobacteria	Actinobacteria	plasma membrane [GO:0005886]; acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]; lipid metabolic process [GO:0006629]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	lipid metabolic process [GO:0006629]		plasma membrane [GO:0005886]		acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]
d1s5ug__d5buwb___1			Proteobacteria	Proteobacteria	plasma membrane [GO:0005886]; acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]; lipid metabolic process [GO:0006629]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	lipid metabolic process [GO:0006629]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d1s5vb__d4wozd___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]	N-acetylneuraminate lyase activity [GO:0008747]
d1s5wb__d5kzeg___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]	cytosol [GO:0005829]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]	N-acetylneuraminate lyase activity [GO:0008747]
d1s5xa__d1ha7u___1	Metazoa		Chordata	Cyanobacteria	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1s5za__d3ztrl___1				Aquificae	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1s5za__d5v6dj___1				Proteobacteria	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1s5zc__d6ay1b___1				Proteobacteria	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1s5ze__d5u2ia1__1				Heterolobosea	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d1s5zf__d1bhne___1		Metazoa		Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; nervous system development [GO:0007399]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; nervous system development [GO:0007399]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1s63a__d3ksqa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]; protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]; protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1s64h__d3d5sb2__1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d1s64h__d3e33b___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1s64l__d1dceb___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	Rab-protein geranylgeranyltransferase complex [GO:0005968]; isoprenoid binding [GO:0019840]; protein heterodimerization activity [GO:0046982]; Rab geranylgeranyltransferase activity [GO:0004663]; Rab GTPase binding [GO:0017137]; zinc ion binding [GO:0008270]; protein geranylgeranylation [GO:0018344]; protein prenylation [GO:0018342]; protein-containing complex assembly [GO:0065003]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	protein-containing complex assembly [GO:0065003]; protein geranylgeranylation [GO:0018344]; protein prenylation [GO:0018342]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	Rab-protein geranylgeranyltransferase complex [GO:0005968]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	isoprenoid binding [GO:0019840]; protein heterodimerization activity [GO:0046982]; Rab geranylgeranyltransferase activity [GO:0004663]; Rab GTPase binding [GO:0017137]; zinc ion binding [GO:0008270]
d1s65a__d2p4jb___1		Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d1s65b__d3pcza___1		Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]						aspartic-type endopeptidase activity [GO:0004190]
d1s66u__d3sw1b___1			Proteobacteria	Proteobacteria	cyclic-guanylate-specific phosphodiesterase activity [GO:0071111]; heme binding [GO:0020037]; magnesium ion binding [GO:0000287]; oxygen sensor activity [GO:0019826]; response to oxygen levels [GO:0070482]	nucleotide binding [GO:0000166]	response to oxygen levels [GO:0070482]				cyclic-guanylate-specific phosphodiesterase activity [GO:0071111]; heme binding [GO:0020037]; magnesium ion binding [GO:0000287]; oxygen sensor activity [GO:0019826]	nucleotide binding [GO:0000166]
d1s69a__d1rtea___1			Cyanobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1s69a__d3wctf___1		Metazoa	Cyanobacteria	Annelida	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]		cell [GO:0005623]; cytoplasm [GO:0005737]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1s6aa__d2qrwg___1			Cyanobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1s6na__d1thda1__1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	protein dimerization activity [GO:0046983]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1s6tb__d4kodc3__1		Metazoa		Chordata		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1s6vb__d1m70a1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	periplasmic space [GO:0042597]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1s6vd__d1lc1a___1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1s70a__d2ahdc___1	Metazoa		Chordata	Euryarchaeota	A band [GO:0031672]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; PTW/PP1 phosphatase complex [GO:0072357]; Z disc [GO:0030018]; 14-3-3 protein binding [GO:0071889]; enzyme inhibitor activity [GO:0004857]; phosphatase regulator activity [GO:0019208]; protein kinase binding [GO:0019901]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; signal transduction [GO:0007165]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; signal transduction [GO:0007165]		A band [GO:0031672]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; PTW/PP1 phosphatase complex [GO:0072357]; Z disc [GO:0030018]		14-3-3 protein binding [GO:0071889]; enzyme inhibitor activity [GO:0004857]; phosphatase regulator activity [GO:0019208]; protein kinase binding [GO:0019901]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1s72b__d1dg1h1__1			Euryarchaeota	Proteobacteria	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	translation [GO:0006412]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	ribosome [GO:0005840]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1s72e2_d1yije1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1s72i__d2qbki1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1s72k__d1vspi1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1s72r__d2qovs1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1s78c2_d5x8lk1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]	
d1s78d2_d5u7ol1__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]	structural molecule activity [GO:0005198]
d1s78e1_d4k07a___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d1s78f1_d3to4b___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1s78f2_d2a0lc1__1	Metazoa		Chordata	Crenarchaeota	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]; regulation of ion transmembrane transport [GO:0034765]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	regulation of ion transmembrane transport [GO:0034765]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	voltage-gated potassium channel complex [GO:0008076]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1s78f2_d2ak4k1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1s7ea2_d1wh8a1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; anatomical structure morphogenesis [GO:0009653]; B cell differentiation [GO:0030183]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cilium assembly [GO:0060271]; endocrine pancreas development [GO:0031018]; endoderm development [GO:0007492]; epithelial cell development [GO:0002064]; glucose metabolic process [GO:0006006]; liver development [GO:0001889]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; positive regulation of cell migration [GO:0030335]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell-matrix adhesion [GO:0001952]; regulation of transcription by RNA polymerase II [GO:0006357]; spleen development [GO:0048536]	extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; cellular response to organic substance [GO:0071310]; cognition [GO:0050890]; Golgi vesicle transport [GO:0048193]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of synapse assembly [GO:0051965]; short-term memory [GO:0007614]	anatomical structure morphogenesis [GO:0009653]; B cell differentiation [GO:0030183]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cilium assembly [GO:0060271]; endocrine pancreas development [GO:0031018]; endoderm development [GO:0007492]; epithelial cell development [GO:0002064]; glucose metabolic process [GO:0006006]; liver development [GO:0001889]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; positive regulation of cell migration [GO:0030335]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell-matrix adhesion [GO:0001952]; regulation of transcription by RNA polymerase II [GO:0006357]; spleen development [GO:0048536]	cellular response to organic substance [GO:0071310]; cognition [GO:0050890]; Golgi vesicle transport [GO:0048193]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of synapse assembly [GO:0051965]; short-term memory [GO:0007614]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]	DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]
d1s7ga__d4jubc2__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]		NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1s7nb__d5t6ca2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; N-acetyltransferase activity [GO:0008080]; peptide-serine-N-acetyltransferase activity [GO:1990189]; ribosomal-protein-alanine N-acetyltransferase activity [GO:0008999]; N-terminal peptidyl-serine acetylation [GO:0017198]	cytoplasm [GO:0005737]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]	N-terminal peptidyl-serine acetylation [GO:0017198]	N-terminal peptidyl-glycine N-myristoylation [GO:0018008]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	N-acetyltransferase activity [GO:0008080]; peptide-serine-N-acetyltransferase activity [GO:1990189]; ribosomal-protein-alanine N-acetyltransferase activity [GO:0008999]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d1s7qb__d2yuva1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; myofibril [GO:0030016]; myosin filament [GO:0032982]; actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; myofibril [GO:0030016]; myosin filament [GO:0032982]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]
d1s7re__d5w24l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1s7ta1_d3bdbe___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	integral component of membrane [GO:0016021]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1s7td1_d1xgua1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1s7te__d1u8ka1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1s7ua1_d1ed3e___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1s7ub__d1ct8c2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1s7ub__d1oaxh___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1s7ud2_d5ksvb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of membrane [GO:0016021]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; macrophage migration inhibitory factor receptor complex [GO:0035692]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; NOS2-CD74 complex [GO:0035693]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; vacuole [GO:0005773]; amyloid-beta binding [GO:0001540]; CD4 receptor binding [GO:0042609]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; macrophage migration inhibitory factor binding [GO:0035718]; MHC class II protein binding [GO:0042289]; MHC class II protein binding, via antigen binding groove [GO:0042658]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase binding [GO:0050998]; protein folding chaperone [GO:0044183]; activation of MAPK activity [GO:0000187]; antigen processing and presentation of endogenous antigen [GO:0019883]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell population proliferation [GO:0008283]; chaperone cofactor-dependent protein refolding [GO:0051085]; defense response [GO:0006952]; immunoglobulin mediated immune response [GO:0016064]; intracellular protein transport [GO:0006886]; leukocyte migration [GO:0050900]; macrophage migration inhibitory factor signaling pathway [GO:0035691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of peptide secretion [GO:0002792]; negative regulation of T cell differentiation [GO:0045581]; negative thymic T cell selection [GO:0045060]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of kinase activity [GO:0033674]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of macrophage migration inhibitory factor signaling pathway [GO:2000448]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of viral entry into host cell [GO:0046598]; positive thymic T cell selection [GO:0045059]; prostaglandin biosynthetic process [GO:0001516]; protein heterotetramerization [GO:0051290]; protein trimerization [GO:0070206]; protein-containing complex assembly [GO:0065003]; regulation of macrophage activation [GO:0043030]; signal transduction [GO:0007165]; T cell selection [GO:0045058]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation of MAPK activity [GO:0000187]; antigen processing and presentation of endogenous antigen [GO:0019883]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell population proliferation [GO:0008283]; chaperone cofactor-dependent protein refolding [GO:0051085]; defense response [GO:0006952]; immunoglobulin mediated immune response [GO:0016064]; intracellular protein transport [GO:0006886]; leukocyte migration [GO:0050900]; macrophage migration inhibitory factor signaling pathway [GO:0035691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of peptide secretion [GO:0002792]; negative regulation of T cell differentiation [GO:0045581]; negative thymic T cell selection [GO:0045060]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of kinase activity [GO:0033674]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of macrophage migration inhibitory factor signaling pathway [GO:2000448]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of viral entry into host cell [GO:0046598]; positive thymic T cell selection [GO:0045059]; prostaglandin biosynthetic process [GO:0001516]; protein-containing complex assembly [GO:0065003]; protein heterotetramerization [GO:0051290]; protein trimerization [GO:0070206]; regulation of macrophage activation [GO:0043030]; signal transduction [GO:0007165]; T cell selection [GO:0045058]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of membrane [GO:0016021]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; macrophage migration inhibitory factor receptor complex [GO:0035692]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; NOS2-CD74 complex [GO:0035693]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; vacuole [GO:0005773]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	amyloid-beta binding [GO:0001540]; CD4 receptor binding [GO:0042609]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; macrophage migration inhibitory factor binding [GO:0035718]; MHC class II protein binding [GO:0042289]; MHC class II protein binding, via antigen binding groove [GO:0042658]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase binding [GO:0050998]; protein folding chaperone [GO:0044183]
d1s7ug2_d4z7uc1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	nutrient reservoir activity [GO:0045735]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	nutrient reservoir activity [GO:0045735]
d1s7uj1_d2wwmd1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1s7va1_d3bz4e1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1s7vb__d1n0xm1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1s7vd1_d3kpqb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1s7wa1_d3cdcb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d1s7we__d5jmrb1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1s7wg1_d1z3gm2__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]
d1s7wh__d1rhha2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1s7wj1_d4nc2b___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	host cell plasma membrane [GO:0020002]; cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	pathogenesis [GO:0009405]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]
d1s7wk__d4f9ld1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor binding [GO:0005102]; activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; cytokine secretion [GO:0050663]; interferon-gamma secretion [GO:0072643]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; cytokine secretion [GO:0050663]; interferon-gamma secretion [GO:0072643]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	signaling receptor binding [GO:0005102]
d1s7xa1_d1i7zd2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1s7xe__d1mcda1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1s7xe__d3g5xa2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1s7xg1_d4nqdh2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1s7xg2_d1im9e2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1s7xh__d4jdvb1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1s7xk__d1lila1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1s7ya__d4meva___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]; transmembrane transport [GO:0055085]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	transmembrane transport [GO:0055085]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	periplasmic space [GO:0042597]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	
d1s7ya__d4o8mb___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; transmembrane transport [GO:0055085]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	transmembrane transport [GO:0055085]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	
d1s7yb__d1y20a___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic branch [GO:0044307]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; synaptic membrane [GO:0097060]; terminal bouton [GO:0043195]; amyloid-beta binding [GO:0001540]; enzyme binding [GO:0019899]; glutamate binding [GO:0016595]; glutamate receptor binding [GO:0035254]; glycine binding [GO:0016594]; ionotropic glutamate receptor activity [GO:0004970]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; phosphatase binding [GO:0019902]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; cellular response to manganese ion [GO:0071287]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning or memory [GO:0007611]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of Schwann cell migration [GO:1900149]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to calcium ion [GO:0051592]; response to fungicide [GO:0060992]; response to organic cyclic compound [GO:0014070]; rhythmic process [GO:0048511]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	cellular response to manganese ion [GO:0071287]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning or memory [GO:0007611]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of Schwann cell migration [GO:1900149]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to calcium ion [GO:0051592]; response to fungicide [GO:0060992]; response to organic cyclic compound [GO:0014070]; rhythmic process [GO:0048511]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic branch [GO:0044307]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; synaptic membrane [GO:0097060]; terminal bouton [GO:0043195]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	amyloid-beta binding [GO:0001540]; enzyme binding [GO:0019899]; glutamate binding [GO:0016595]; glutamate receptor binding [GO:0035254]; glycine binding [GO:0016594]; ionotropic glutamate receptor activity [GO:0004970]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; signaling receptor binding [GO:0005102]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d1s82a__d1elga___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1s84a__d3th4h___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	digestion [GO:0007586]; proteolysis [GO:0006508]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d1s89b__d2b1ga1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1s89b__d2xw6b1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]		methylglyoxal synthase activity [GO:0008929]	methylglyoxal synthase activity [GO:0008929]
d1s89c__d1cs0a2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1s89d__d1egha___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	methylglyoxal synthase activity [GO:0008929]
d1s89e__d1pkxa1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	methylglyoxal synthase activity [GO:0008929]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1s89f__d1wo8a1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]		methylglyoxal synthase activity [GO:0008929]	methylglyoxal synthase activity [GO:0008929]
d1s89f__d2iu0a1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1s8aa__d1vmdb1__1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	methylglyoxal synthase activity [GO:0008929]
d1s8ab__d1wo8e___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]		methylglyoxal synthase activity [GO:0008929]	methylglyoxal synthase activity [GO:0008929]
d1s8ac__d1pkxc1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	methylglyoxal synthase activity [GO:0008929]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1s8cb__d4g7ua___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1s8cd__d1ozeb___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1s8cd__d5uc9d___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d1s8da1_d3mckl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1s8db__d4ydkl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d1s8ea__d4b2oa___1			Euryarchaeota	Firmicutes	3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]; double-strand break repair [GO:0006302]	cytoplasm [GO:0005737]; 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]	double-strand break repair [GO:0006302]			cytoplasm [GO:0005737]	3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]
d1s8ha__d1ceha___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]
d1s8ia__d2wq5a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]
d1s8ia__d3vbza___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]
d1s8na__d2flka___1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; RNA binding [GO:0003723]; phosphorelay signal transduction system [GO:0000160]; transcription antitermination [GO:0031564]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; transcription antitermination [GO:0031564]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	anion binding [GO:0043168]; RNA binding [GO:0003723]	metal ion binding [GO:0046872]
d1s95a__d2qfpd2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	extracellular region [GO:0005576]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]
d1s95b__d1xzwb2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	extracellular region [GO:0005576]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]
d1s97a1_d2uvra1__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d1s9cc1_d5egkd___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]; alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	thiolester hydrolase activity [GO:0016790]	alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]		cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]		17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]	thiolester hydrolase activity [GO:0016790]
d1s9ce1_d1pn4b2__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]; alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	peroxisome [GO:0005777]; isomerase activity [GO:0016853]; lyase activity [GO:0016829]; oxidoreductase activity [GO:0016491]; fatty acid beta-oxidation [GO:0006635]	alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	fatty acid beta-oxidation [GO:0006635]	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	peroxisome [GO:0005777]	17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]	isomerase activity [GO:0016853]; lyase activity [GO:0016829]; oxidoreductase activity [GO:0016491]
d1s9cf1_d5kl9a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]; alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	plasma membrane [GO:0005886]; acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]; lipid metabolic process [GO:0006629]	alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	lipid metabolic process [GO:0006629]	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	plasma membrane [GO:0005886]	17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]	acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]
d1s9cg1_d3doyd___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]; alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	cytoplasm [GO:0005737]	17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d1s9ha1_d1xcpc1__1				Proteobacteria	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA replication [GO:0006260]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; suppression by virus of G2/M transition of host mitotic cell cycle [GO:0039592]; viral DNA genome replication [GO:0039693]; viral entry via permeabilization of inner membrane [GO:0099008]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	DNA replication [GO:0006260]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; suppression by virus of G2/M transition of host mitotic cell cycle [GO:0039592]; viral DNA genome replication [GO:0039693]; viral entry via permeabilization of inner membrane [GO:0099008]	nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1s9kc1_d3jv5b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	Bcl3/NF-kappaB2 complex [GO:0033257]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; aging [GO:0007568]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; rhythmic process [GO:0048511]; spleen development [GO:0048536]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	aging [GO:0007568]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; rhythmic process [GO:0048511]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	Bcl3/NF-kappaB2 complex [GO:0033257]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d1s9kc2_d1gjia2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; apoptotic DNA fragmentation [GO:0006309]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	apoptotic DNA fragmentation [GO:0006309]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d1s9kc2_d5a7bb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1s9wa1_d2dm2a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; podosome [GO:0002102]; ruffle [GO:0001726]; Z disc [GO:0030018]; actin binding [GO:0003779]; cell-cell adhesion mediator activity [GO:0098632]; muscle alpha-actinin binding [GO:0051371]; actin cytoskeleton organization [GO:0030036]; axon guidance [GO:0007411]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; dendrite self-avoidance [GO:0070593]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte development [GO:0003334]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin cytoskeleton organization [GO:0030036]; axon guidance [GO:0007411]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; dendrite self-avoidance [GO:0070593]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte development [GO:0003334]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; podosome [GO:0002102]; ruffle [GO:0001726]; Z disc [GO:0030018]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; cell-cell adhesion mediator activity [GO:0098632]; muscle alpha-actinin binding [GO:0051371]
d1s9wb1_d5eblb2__1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	voltage-gated potassium channel complex [GO:0008076]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1s9xa1_d1mcoh4__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1s9xa2_d4huua1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1s9xb1_d4amkl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1s9ya1_d2fjhl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]
d1sa4b__d3cu7be__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]; protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]; protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d1sa8a__d1ifca___1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]	fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]	fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1sa8a__d2w2ba___1	Metazoa		Chordata	Firmicutes	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]	carboxy-lyase activity [GO:0016831]	fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]		apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]		fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	carboxy-lyase activity [GO:0016831]
d1saca__d1ulca___1	Metazoa	Fungi	Chordata	Basidiomycota	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]
d1saca__d3l2yj___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1sacb__d3azxa___1	Metazoa		Chordata	Thermotogae	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate metabolic process [GO:0005975]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1sacc__d1bxha___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1sacc__d3l2yl___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1sata2_d5uuaa___1			Proteobacteria	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; pathogenesis [GO:0009405]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	pathogenesis [GO:0009405]; proteolysis [GO:0006508]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1saua__d2v4jf___1			Euryarchaeota	Proteobacteria		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]		sulfur compound metabolic process [GO:0006790]				4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d1saxa__d2p7cb1__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1saxb__d1sd6a___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1sb3a2_d1hlra8__1			Proteobacteria		4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]						4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	
d1sb3c2_d1qlae3__1			Proteobacteria		4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]						4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	
d1sb3c2_d1qofb___1			Proteobacteria	Cyanobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1sb3d1_d3b9jc1__1		Metazoa	Proteobacteria	Chordata	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1sb3f2_d4jx1g___1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1sbba2_d2hvka1__1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]			extracellular region [GO:0005576]	voltage-gated potassium channel complex [GO:0008076]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1sbbc1_d1himj1__1			Firmicutes	Negarnaviricota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	host cell surface receptor binding [GO:0046789]
d1sbbc2_d3qa3c1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	extracellular region [GO:0005576]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]
d1sbbd2_d3owel2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d1sbca__d5wslc___1			Firmicutes	Deinococcus-Thermus	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1sbfa__d5glub1__1	Viridiplantae	Metazoa	Streptophyta	Nematoda (roundworms)	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d1sbga__d4y6mb___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1sbja__d1irjd___1	Metazoa	Metazoa	Chordata	Chordata	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	troponin complex [GO:0005861]	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1sbne__d5wslb___1			Firmicutes	Deinococcus-Thermus	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	serine-type endopeptidase activity [GO:0004252]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1sbqb__d4eu5a1__1			Tenericutes	Proteobacteria	cytoplasm [GO:0005737]; 5-formyltetrahydrofolate cyclo-ligase activity [GO:0030272]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]		acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	cytoplasm [GO:0005737]		5-formyltetrahydrofolate cyclo-ligase activity [GO:0030272]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d1sbsh1_d12e8h2__1												
d1sbsl2_d1iile1__1		Metazoa		Chordata		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]		angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1sbwa__d1toc.3__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]
d1sbwa__d4ylua___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]
d1sc5a3_d3dxjf1__1			Aquificae	Deinococcus-Thermus	sigma factor antagonist complex [GO:1903865]; antisigma factor binding [GO:0045152]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; sigma factor activity [GO:0016987]; DNA-templated transcription, initiation [GO:0006352]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	DNA-templated transcription, initiation [GO:0006352]	transcription, DNA-templated [GO:0006351]	sigma factor antagonist complex [GO:1903865]		antisigma factor binding [GO:0045152]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; sigma factor activity [GO:0016987]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d1scaa__d1v6ca___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1scda__d3i37x___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1scha__d3wxoa1__1	Viridiplantae		Streptophyta	Cyanobacteria	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1schb__d4p4qa___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1scra__d1rita___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1sctd__d3s48d___1		Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1scth__d1j3zd___1		Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1scub2_d1i7nb2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cell junction [GO:0030054]; extrinsic component of synaptic vesicle membrane [GO:0098850]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; cytoskeletal protein binding [GO:0008092]; neurotransmitter secretion [GO:0007269]; regulation of neurotransmitter secretion [GO:0046928]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	neurotransmitter secretion [GO:0007269]; regulation of neurotransmitter secretion [GO:0046928]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cell junction [GO:0030054]; extrinsic component of synaptic vesicle membrane [GO:0098850]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; cytoskeletal protein binding [GO:0008092]
d1scue1_d1cqja2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d1sd0a1_d3l2gq1__1	Metazoa		Arthropoda		cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]		arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	
d1sd5a__d5hm6a___1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; RNA binding [GO:0003723]; phosphorelay signal transduction system [GO:0000160]; transcription antitermination [GO:0031564]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; transcription antitermination [GO:0031564]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cell wall [GO:0005618]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; RNA binding [GO:0003723]	DNA binding [GO:0003677]
d1sd9a__d4v2lb___1		Metazoa	Proteobacteria	Arthropoda	arsenate reductase (glutaredoxin) activity [GO:0008794]; response to arsenic-containing substance [GO:0046685]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	response to arsenic-containing substance [GO:0046685]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]	arsenate reductase (glutaredoxin) activity [GO:0008794]	protein disulfide oxidoreductase activity [GO:0015035]
d1sddb4_d2vxjg___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; copper ion binding [GO:0005507]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	blood circulation [GO:0008015]; blood coagulation [GO:0007596]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]	carbohydrate binding [GO:0030246]
d1sdkc__d1do7a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1sdkd__d3bj2b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1sdlb__d4l1el___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1sdlc__d1fawa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1sdlc__d1uvya___1	Metazoa		Chordata	Ciliophora	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1sdsb__d1yj9f1__1			Euryarchaeota	Euryarchaeota	cytosolic large ribosomal subunit [GO:0022625]; small nucleolar ribonucleoprotein complex [GO:0005732]; box C/D snoRNA binding [GO:0034512]; ribonuclease P activity [GO:0004526]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; box C/D snoRNP assembly [GO:0000492]; maturation of LSU-rRNA [GO:0000470]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	box C/D snoRNP assembly [GO:0000492]; maturation of LSU-rRNA [GO:0000470]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]; small nucleolar ribonucleoprotein complex [GO:0005732]	ribosome [GO:0005840]	box C/D snoRNA binding [GO:0034512]; ribonuclease P activity [GO:0004526]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1sdtb__d5p2ea___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1sdua__d2o4kb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1sdub__d5e5jb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]
d1sdwa1_d1pgsa2__1	Metazoa		Chordata	Bacteroidetes	cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]; central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]	central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]		cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]
d1sdx.1_d1fqea___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d1sdyc__d1sose___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1sdyc__d2jlpb___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; heparin binding [GO:0008201]; superoxide dismutase activity [GO:0004784]; cellular response to oxidative stress [GO:0034599]; removal of superoxide radicals [GO:0019430]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]	age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	cellular response to oxidative stress [GO:0034599]; removal of superoxide radicals [GO:0019430]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]	copper ion binding [GO:0005507]; heparin binding [GO:0008201]; superoxide dismutase activity [GO:0004784]
d1se1a4_d2caqa2__1		Metazoa		Platyhelminthes		glutathione transferase activity [GO:0004364]						glutathione transferase activity [GO:0004364]
d1se1b3_d2k0ra1__1				Proteobacteria		cell [GO:0005623]; integral component of plasma membrane [GO:0005887]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]		cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]		cell [GO:0005623]; integral component of plasma membrane [GO:0005887]		electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1se1b4_d1j08a1__1				Euryarchaeota		cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]		electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d1se3a2_d4uduc2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d1se4a1_d5lzjc___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d1se9a__d5dprd___1	Viridiplantae	Metazoa	Streptophyta	Chordata	plasma membrane [GO:0005886]	autolysosome [GO:0044754]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; microtubule [GO:0005874]; organelle membrane [GO:0031090]; synapse [GO:0045202]; microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; phospholipid binding [GO:0005543]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]		autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]	plasma membrane [GO:0005886]	autolysosome [GO:0044754]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; microtubule [GO:0005874]; organelle membrane [GO:0031090]; synapse [GO:0045202]		microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; phospholipid binding [GO:0005543]; ubiquitin protein ligase binding [GO:0031625]
d1seba1_d2dqdl___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1seba2_d4z7ud1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	nutrient reservoir activity [GO:0045735]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	nutrient reservoir activity [GO:0045735]
d1sebe2_d3m1be1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1sefa__d4zu7f1__1			Firmicutes	Firmicutes								
d1seja2_d4e5oa___1		Metazoa	Apicomplexa	Chordata	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; mRNA binding [GO:0003729]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; regulation of translation [GO:0006417]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; regulation of translation [GO:0006417]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	cofactor binding [GO:0048037]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; mRNA binding [GO:0003729]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1sejb1_d3jw3b1__1			Apicomplexa	Firmicutes	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1seje1_d3fl8d1__1			Apicomplexa	Firmicutes	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1sena__d4txoe___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; peptide disulfide oxidoreductase activity [GO:0015037]; protein-disulfide reductase (glutathione) activity [GO:0019153]; cell redox homeostasis [GO:0045454]; negative regulation of cell death [GO:0060548]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell redox homeostasis [GO:0045454]; negative regulation of cell death [GO:0060548]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	peptide disulfide oxidoreductase activity [GO:0015037]; protein-disulfide reductase (glutathione) activity [GO:0019153]	oxidoreductase activity [GO:0016491]
d1serb2_d1yfsb2__1			Deinococcus-Thermus	Aquificae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; serine binding [GO:0070905]; serine-tRNA ligase activity [GO:0004828]; tRNA binding [GO:0000049]; selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	cytosol [GO:0005829]; alanine-tRNA ligase activity [GO:0004813]; amino acid binding [GO:0016597]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; alanyl-tRNA aminoacylation [GO:0006419]; tRNA modification [GO:0006400]	selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	alanyl-tRNA aminoacylation [GO:0006419]; tRNA modification [GO:0006400]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; serine binding [GO:0070905]; serine-tRNA ligase activity [GO:0004828]; tRNA binding [GO:0000049]	alanine-tRNA ligase activity [GO:0004813]; amino acid binding [GO:0016597]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1serb2_d5elod2__1			Deinococcus-Thermus	Apicomplexa	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; serine binding [GO:0070905]; serine-tRNA ligase activity [GO:0004828]; tRNA binding [GO:0000049]; selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	lysyl-tRNA aminoacylation [GO:0006430]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; serine binding [GO:0070905]; serine-tRNA ligase activity [GO:0004828]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; nucleic acid binding [GO:0003676]
d1sesb2_d1lylc2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; serine binding [GO:0070905]; serine-tRNA ligase activity [GO:0004828]; tRNA binding [GO:0000049]; selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; serine binding [GO:0070905]; serine-tRNA ligase activity [GO:0004828]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]
d1seta1_d1iywb1__1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; serine binding [GO:0070905]; serine-tRNA ligase activity [GO:0004828]; tRNA binding [GO:0000049]; selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; valine-tRNA ligase activity [GO:0004832]; valyl-tRNA aminoacylation [GO:0006438]	selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	valyl-tRNA aminoacylation [GO:0006438]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; serine binding [GO:0070905]; serine-tRNA ligase activity [GO:0004828]; tRNA binding [GO:0000049]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; valine-tRNA ligase activity [GO:0004832]
d1setb2_d4ttva1__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; serine binding [GO:0070905]; serine-tRNA ligase activity [GO:0004828]; tRNA binding [GO:0000049]; selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; serine binding [GO:0070905]; serine-tRNA ligase activity [GO:0004828]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]
d1seva2_d1i10f2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	glyoxysome [GO:0009514]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-malate dehydrogenase activity [GO:0030060]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1sevb1_d1p44d___1	Viridiplantae		Streptophyta	Actinobacteria	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	glyoxysome [GO:0009514]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	L-malate dehydrogenase activity [GO:0030060]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d1sf2c__d1elub___1			Proteobacteria	Cyanobacteria	cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	lyase activity [GO:0016829]	arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]		cytosol [GO:0005829]		4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]	lyase activity [GO:0016829]
d1sf2d__d1wsta1__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]	arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]		4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1sf4a__d1oufa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1sf4a__d4i7ma1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1sf7a__d2f2qa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1sfba__d1gb5a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1sffb__d5lucm___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]; cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]	arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]	cytosol [GO:0005829]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]	alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]
d1sffc__d2vi9a___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]
d1sfhb__d5x1bb2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]		ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1sfq.1_d1t32a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	azurophil granule lumen [GO:0035578]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; angiotensin maturation [GO:0002003]; antibacterial humoral response [GO:0019731]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of gram-positive bacterium [GO:0070946]; positive regulation of immune response [GO:0050778]; protein phosphorylation [GO:0006468]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	angiotensin maturation [GO:0002003]; antibacterial humoral response [GO:0019731]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of gram-positive bacterium [GO:0070946]; positive regulation of immune response [GO:0050778]; protein phosphorylation [GO:0006468]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	azurophil granule lumen [GO:0035578]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	heparin binding [GO:0008201]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1sfq.1_d1ym0a___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	kinase activity [GO:0016301]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	kinase activity [GO:0016301]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1sfsa__d4im4d___1			Firmicutes	Firmicutes		extracellular region [GO:0005576]; acetylxylan esterase activity [GO:0046555]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; glucomannan catabolic process [GO:2000884]; xylan catabolic process [GO:0045493]		cellulose catabolic process [GO:0030245]; glucomannan catabolic process [GO:2000884]; xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]		acetylxylan esterase activity [GO:0046555]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d1sfua__d4p5oa2__1		Metazoa		Chordata	double-stranded RNA adenosine deaminase activity [GO:0003726]; peptidase activity [GO:0008233]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723]; suppression by virus of host innate immune response [GO:0039503]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	suppression by virus of host innate immune response [GO:0039503]	anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	double-stranded RNA adenosine deaminase activity [GO:0003726]; peptidase activity [GO:0008233]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1sfub__d1xmka1__1		Metazoa		Chordata	double-stranded RNA adenosine deaminase activity [GO:0003726]; peptidase activity [GO:0008233]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723]; suppression by virus of host innate immune response [GO:0039503]	cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; supraspliceosomal complex [GO:0044530]; DNA binding [GO:0003677]; double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251]; adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; RNA processing [GO:0006396]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; type I interferon signaling pathway [GO:0060337]	suppression by virus of host innate immune response [GO:0039503]	adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; RNA processing [GO:0006396]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; type I interferon signaling pathway [GO:0060337]		cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; supraspliceosomal complex [GO:0044530]	double-stranded RNA adenosine deaminase activity [GO:0003726]; peptidase activity [GO:0008233]; protein serine/threonine kinase activity [GO:0004674]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251]
d1sfyb__d2ymzb1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d1sfyc__d1qnya___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1sfyd__d2dvdb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1sfyf__d3nv1a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]
d1sg0a__d2flva___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1sg0b__d2ohih2__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1sg8.2_d1a3e.1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d1sgee__d2snwb___1			Actinobacteria		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	serine-type endopeptidase activity [GO:0004252]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]
d1sgee__d3m7ta___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1sgha1_d4ny0a2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]; beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein-containing complex assembly [GO:0065003]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]	beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]	actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]
d1sgha2_d5he0a3__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]; beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]; alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]; cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein phosphorylation [GO:0006468]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein-containing complex assembly [GO:0065003]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein phosphorylation [GO:0006468]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]	beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]	alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]
d1sgha3_d1h4ra3__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]; beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein-containing complex assembly [GO:0065003]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]	actin binding [GO:0003779]
d1sgi.1_d2tgta___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1sgjb__d1dxeb___1			Deinococcus-Thermus	Proteobacteria	lyase activity [GO:0016829]; magnesium ion binding [GO:0000287]; oxaloacetate metabolic process [GO:0006107]	cytoplasm [GO:0005737]; 2-dehydro-3-deoxyglucarate aldolase activity [GO:0008672]; aldehyde-lyase activity [GO:0016832]; carbon-carbon lyase activity [GO:0016830]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]; galactarate catabolic process [GO:0046392]; glucarate catabolic process [GO:0019394]	oxaloacetate metabolic process [GO:0006107]	D-glucarate catabolic process [GO:0042838]; galactarate catabolic process [GO:0046392]; glucarate catabolic process [GO:0019394]		cytoplasm [GO:0005737]	lyase activity [GO:0016829]; magnesium ion binding [GO:0000287]	2-dehydro-3-deoxyglucarate aldolase activity [GO:0008672]; aldehyde-lyase activity [GO:0016832]; carbon-carbon lyase activity [GO:0016830]; magnesium ion binding [GO:0000287]
d1sgjc__d1m3uj___1			Deinococcus-Thermus	Proteobacteria	lyase activity [GO:0016829]; magnesium ion binding [GO:0000287]; oxaloacetate metabolic process [GO:0006107]	cytosol [GO:0005829]; membrane [GO:0016020]; 3-methyl-2-oxobutanoate hydroxymethyltransferase activity [GO:0003864]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]	oxaloacetate metabolic process [GO:0006107]	pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]		cytosol [GO:0005829]; membrane [GO:0016020]	lyase activity [GO:0016829]; magnesium ion binding [GO:0000287]	3-methyl-2-oxobutanoate hydroxymethyltransferase activity [GO:0003864]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1sgne__d4abaa___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1sgpe__d2o8la___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1sgpe__d2tioa___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1sgre__d5eqsa1__1			Actinobacteria		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; transformation of host cell by virus [GO:0019087]		transformation of host cell by virus [GO:0019087]	extracellular region [GO:0005576]		serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d1sgua__d3ggvg___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1sgwa1_d2pcja___1			Euryarchaeota	Aquificae	ATP binding [GO:0005524]; ATPase activity [GO:0016887]	plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; lipoprotein releasing activity [GO:0140306]; transmembrane transporter activity [GO:0022857]; lipoprotein transport [GO:0042953]; transmembrane transport [GO:0055085]		lipoprotein transport [GO:0042953]; transmembrane transport [GO:0055085]		plasma membrane [GO:0005886]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; lipoprotein releasing activity [GO:0140306]; transmembrane transporter activity [GO:0022857]
d1sgxa5_d2r69a1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1sgxb8_d3ly6c4__1		Metazoa		Chordata		cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]		apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]		cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1sgzc__d4coeb___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1sh5a2_d4q57b1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; protein N-terminus binding [GO:0047485]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; response to nutrient [GO:0007584]; wound healing [GO:0042060]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; response to nutrient [GO:0007584]; wound healing [GO:0042060]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; protein N-terminus binding [GO:0047485]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1sh5b1_d1sh6a2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; protein N-terminus binding [GO:0047485]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; response to nutrient [GO:0007584]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; protein N-terminus binding [GO:0047485]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; response to nutrient [GO:0007584]; wound healing [GO:0042060]	hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; response to nutrient [GO:0007584]; wound healing [GO:0042060]	hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; response to nutrient [GO:0007584]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; protein N-terminus binding [GO:0047485]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; protein N-terminus binding [GO:0047485]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]
d1sh5b2_d5a36b2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; protein N-terminus binding [GO:0047485]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; response to nutrient [GO:0007584]; wound healing [GO:0042060]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; pseudopodium [GO:0031143]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]; actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; response to nutrient [GO:0007584]; wound healing [GO:0042060]	actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; pseudopodium [GO:0031143]; Z disc [GO:0030018]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; protein N-terminus binding [GO:0047485]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]
d1sh6a2_d1wkub1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; protein N-terminus binding [GO:0047485]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; response to nutrient [GO:0007584]; wound healing [GO:0042060]	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; response to nutrient [GO:0007584]; wound healing [GO:0042060]	focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; protein N-terminus binding [GO:0047485]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]
d1sh9b__d1xl2b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1shca__d1oqna___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; plasma membrane [GO:0005886]; Shc-EGFR complex [GO:0070435]; ephrin receptor binding [GO:0046875]; epidermal growth factor binding [GO:0048408]; epidermal growth factor receptor binding [GO:0005154]; insulin receptor binding [GO:0005158]; insulin-like growth factor receptor binding [GO:0005159]; neurotrophin TRKA receptor binding [GO:0005168]; phospholipid binding [GO:0005543]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; receptor tyrosine kinase binding [GO:0030971]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; actin cytoskeleton reorganization [GO:0031532]; activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell-cell adhesion [GO:0098609]; cellular response to growth factor stimulus [GO:0071363]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-2-mediated signaling pathway [GO:0038110]; IRE1-mediated unfolded protein response [GO:0036498]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of transcription, DNA-templated [GO:0045893]; Ras protein signal transduction [GO:0007265]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of growth [GO:0040008]; regulation of superoxide metabolic process [GO:0090322]; viral process [GO:0016032]	apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; growth cone [GO:0030426]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; integral component of membrane [GO:0016021]; main axon [GO:0044304]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; terminal bouton [GO:0043195]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; growth factor receptor binding [GO:0070851]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; peptidase activator activity [GO:0016504]; PTB domain binding [GO:0051425]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron differentiation [GO:0045665]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein binding [GO:0032092]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein phosphorylation [GO:0006468]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of translation [GO:0006417]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	actin cytoskeleton reorganization [GO:0031532]; activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell-cell adhesion [GO:0098609]; cellular response to growth factor stimulus [GO:0071363]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-2-mediated signaling pathway [GO:0038110]; IRE1-mediated unfolded protein response [GO:0036498]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of transcription, DNA-templated [GO:0045893]; Ras protein signal transduction [GO:0007265]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of growth [GO:0040008]; regulation of superoxide metabolic process [GO:0090322]; viral process [GO:0016032]	activation of MAPK activity [GO:0000187]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron differentiation [GO:0045665]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein binding [GO:0032092]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein phosphorylation [GO:0006468]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of translation [GO:0006417]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; plasma membrane [GO:0005886]; Shc-EGFR complex [GO:0070435]	apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; growth cone [GO:0030426]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; integral component of membrane [GO:0016021]; main axon [GO:0044304]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; terminal bouton [GO:0043195]	ephrin receptor binding [GO:0046875]; epidermal growth factor binding [GO:0048408]; epidermal growth factor receptor binding [GO:0005154]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; neurotrophin TRKA receptor binding [GO:0005168]; phospholipid binding [GO:0005543]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; receptor tyrosine kinase binding [GO:0030971]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]	DNA binding [GO:0003677]; enzyme binding [GO:0019899]; growth factor receptor binding [GO:0070851]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; peptidase activator activity [GO:0016504]; PTB domain binding [GO:0051425]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; transition metal ion binding [GO:0046914]
d1shqa1_d1alha___1	Metazoa		Arthropoda	Proteobacteria	alkaline phosphatase activity [GO:0004035]; metal ion binding [GO:0046872]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]		dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkaline phosphatase activity [GO:0004035]; metal ion binding [GO:0046872]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1shrb__d1b33j___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; photosynthesis [GO:0015979]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	photosynthesis [GO:0015979]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1shrb__d2r4wa___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1shrc__d2hhdd___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1shrc__d5fvbk___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1shsa__d2xcmc___1		Viridiplantae	Euryarchaeota	Streptophyta	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; cellular response to auxin stimulus [GO:0071365]; defense response [GO:0006952]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; protein stabilization [GO:0050821]; regulation of defense response to fungus, incompatible interaction [GO:2000072]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cellular response to auxin stimulus [GO:0071365]; defense response [GO:0006952]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; protein stabilization [GO:0050821]; regulation of defense response to fungus, incompatible interaction [GO:2000072]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	
d1shsb__d2h50f1__1		Viridiplantae	Euryarchaeota	Streptophyta	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]
d1shsb__d5j7na___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]		identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	
d1shse__d4yl9a___1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]		identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1shsh__d3vqla___1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]		identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	
d1shux__d5hj2c___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]; reproductive process [GO:0022414]; toxin transport [GO:1901998]	axon terminus [GO:0043679]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha2-beta1 complex [GO:0034666]; integrin complex [GO:0008305]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; collagen receptor activity [GO:0038064]; heparan sulfate proteoglycan binding [GO:0043395]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; virus receptor activity [GO:0001618]; animal organ morphogenesis [GO:0009887]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell population proliferation [GO:0008283]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; collagen-activated signaling pathway [GO:0038065]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; focal adhesion assembly [GO:0048041]; hepatocyte differentiation [GO:0070365]; hypotonic response [GO:0006971]; integrin-mediated signaling pathway [GO:0007229]; mammary gland development [GO:0030879]; mesodermal cell differentiation [GO:0048333]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell projection organization [GO:0031346]; positive regulation of collagen binding [GO:0033343]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of translation [GO:0045727]; positive regulation of transmission of nerve impulse [GO:0051971]; response to amine [GO:0014075]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to L-ascorbic acid [GO:0033591]; response to muscle activity [GO:0014850]; response to parathyroid hormone [GO:0071107]; skin morphogenesis [GO:0043589]; substrate-dependent cell migration [GO:0006929]	reproductive process [GO:0022414]; toxin transport [GO:1901998]	animal organ morphogenesis [GO:0009887]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell population proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; collagen-activated signaling pathway [GO:0038065]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; focal adhesion assembly [GO:0048041]; hepatocyte differentiation [GO:0070365]; hypotonic response [GO:0006971]; integrin-mediated signaling pathway [GO:0007229]; mammary gland development [GO:0030879]; mesodermal cell differentiation [GO:0048333]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell projection organization [GO:0031346]; positive regulation of collagen binding [GO:0033343]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of translation [GO:0045727]; positive regulation of transmission of nerve impulse [GO:0051971]; response to amine [GO:0014075]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to L-ascorbic acid [GO:0033591]; response to muscle activity [GO:0014850]; response to parathyroid hormone [GO:0071107]; skin morphogenesis [GO:0043589]; substrate-dependent cell migration [GO:0006929]	cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	axon terminus [GO:0043679]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha2-beta1 complex [GO:0034666]; integrin complex [GO:0008305]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	amyloid-beta binding [GO:0001540]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; collagen receptor activity [GO:0038064]; heparan sulfate proteoglycan binding [GO:0043395]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; virus receptor activity [GO:0001618]
d1shwb__d2wo2a1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; ephrin receptor binding [GO:0046875]; virus receptor activity [GO:0001618]; anatomical structure morphogenesis [GO:0009653]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; ephrin receptor signaling pathway [GO:0048013]; lymph vessel development [GO:0001945]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of neuron projection development [GO:0010977]; nephric duct morphogenesis [GO:0072178]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of neuron death [GO:1901216]; presynapse assembly [GO:0099054]; regulation of chemotaxis [GO:0050920]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; T cell costimulation [GO:0031295]; venous blood vessel morphogenesis [GO:0048845]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]	anatomical structure morphogenesis [GO:0009653]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; ephrin receptor signaling pathway [GO:0048013]; lymph vessel development [GO:0001945]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of neuron projection development [GO:0010977]; nephric duct morphogenesis [GO:0072178]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of neuron death [GO:1901216]; presynapse assembly [GO:0099054]; regulation of chemotaxis [GO:0050920]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; T cell costimulation [GO:0031295]; venous blood vessel morphogenesis [GO:0048845]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]	focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	ephrin receptor binding [GO:0046875]; virus receptor activity [GO:0001618]
d1shza1_d2rgna1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	caveola [GO:0005901]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; alkylglycerophosphoethanolamine phosphodiesterase activity [GO:0047391]; G protein-coupled receptor binding [GO:0001664]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTP binding [GO:0005525]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; type 2A serotonin receptor binding [GO:0031826]; action potential [GO:0001508]; activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; developmental pigmentation [GO:0048066]; embryonic digit morphogenesis [GO:0042733]; forebrain neuron development [GO:0021884]; G protein-coupled receptor signaling pathway [GO:0007186]; glutamate receptor signaling pathway [GO:0007215]; heart development [GO:0007507]; maternal behavior [GO:0042711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein kinase activity [GO:0006469]; neuron remodeling [GO:0016322]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of smooth muscle cell proliferation [GO:0048661]; post-embryonic development [GO:0009791]; protein stabilization [GO:0050821]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of melanocyte differentiation [GO:0045634]; skeletal system development [GO:0001501]	adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	action potential [GO:0001508]; activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; developmental pigmentation [GO:0048066]; embryonic digit morphogenesis [GO:0042733]; forebrain neuron development [GO:0021884]; glutamate receptor signaling pathway [GO:0007215]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; maternal behavior [GO:0042711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein kinase activity [GO:0006469]; neuron remodeling [GO:0016322]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of smooth muscle cell proliferation [GO:0048661]; post-embryonic development [GO:0009791]; protein stabilization [GO:0050821]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of melanocyte differentiation [GO:0045634]; skeletal system development [GO:0001501]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	caveola [GO:0005901]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	alkylglycerophosphoethanolamine phosphodiesterase activity [GO:0047391]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; type 2A serotonin receptor binding [GO:0031826]
d1si1a__d1n04a1__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]		acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]		cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	metal ion binding [GO:0046872]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]
d1si4a__d4l1ej___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1si7a__d1k8wa5__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]; pseudouridine synthesis [GO:0001522]; tRNA pseudouridine synthesis [GO:0031119]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]; mRNA pseudouridine synthesis [GO:1990481]; pseudouridine synthesis [GO:0001522]; RNA folding [GO:0034337]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	pseudouridine synthesis [GO:0001522]; tRNA pseudouridine synthesis [GO:0031119]	mRNA pseudouridine synthesis [GO:1990481]; pseudouridine synthesis [GO:0001522]; RNA folding [GO:0034337]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]	pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]
d1si9b__d2znzc2__1	Viridiplantae		Streptophyta	Euryarchaeota		DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]						DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d1sibi__d1csei___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1sidd__d4fmih___1					host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]		host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]	viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1sija1_d2w3sc2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1sioa__d1tm4e___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1siva__d5p66a___1		Fungi		Ascomycota	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1siwa1_d3hu1b1__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1sixa1_d2y1ta___1			Actinobacteria	Firmicutes	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1siya__d2mala___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lipid binding [GO:0008289]; defense response to fungus [GO:0050832]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]; lipid transport [GO:0006869]	lipid binding [GO:0008289]; lipid transport [GO:0006869]	defense response to fungus [GO:0050832]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]; lipid transport [GO:0006869]	lipid transport [GO:0006869]			lipid binding [GO:0008289]	lipid binding [GO:0008289]
d1sj2a1_d4oq7a___1		Fungi	Actinobacteria	Ascomycota	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	response to oxidative stress [GO:0006979]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1sj2a1_d5ksfa2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1sj2b1_d1itkb1__1			Actinobacteria	Euryarchaeota	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1sj9e__d3p0ee___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytosol [GO:0005829]; type III intermediate filament [GO:0045098]; identical protein binding [GO:0042802]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine metabolic process [GO:0046108]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine metabolic process [GO:0046108]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; type III intermediate filament [GO:0045098]	uridine phosphorylase activity [GO:0004850]	identical protein binding [GO:0042802]; uridine phosphorylase activity [GO:0004850]
d1sjac1_d1jpmb1__1			Actinobacteria	Firmicutes	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	menaquinone biosynthetic process [GO:0009234]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d1sjac2_d1p48a2__1		Fungi	Actinobacteria	Ascomycota	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	menaquinone biosynthetic process [GO:0009234]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1sjbb1_d4il0d2__1			Actinobacteria	Proteobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; cellular catabolic process [GO:0044248]	menaquinone biosynthetic process [GO:0009234]	cellular amino acid catabolic process [GO:0009063]; cellular catabolic process [GO:0044248]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]
d1sjcc1_d3ritd2__1			Actinobacteria	Proteobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]	menaquinone biosynthetic process [GO:0009234]	catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d1sjcd1_d2gl5b1__1			Actinobacteria	Proteobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	metal ion binding [GO:0046872]	menaquinone biosynthetic process [GO:0009234]				hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]
d1sjcd1_d4mggf2__1			Actinobacteria	Proteobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	amino acid binding [GO:0016597]; hydro-lyase activity [GO:0016836]; isomerase activity [GO:0016853]; magnesium ion binding [GO:0000287]; alpha-amino acid metabolic process [GO:1901605]; cellular response to amino acid stimulus [GO:0071230]	menaquinone biosynthetic process [GO:0009234]	alpha-amino acid metabolic process [GO:1901605]; cellular response to amino acid stimulus [GO:0071230]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	amino acid binding [GO:0016597]; hydro-lyase activity [GO:0016836]; isomerase activity [GO:0016853]; magnesium ion binding [GO:0000287]
d1sjda1_d1ec8a1__1			Actinobacteria	Proteobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	menaquinone biosynthetic process [GO:0009234]	D-glucarate catabolic process [GO:0042838]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d1sjdb1_d4gmec2__1			Actinobacteria	Proteobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	menaquinone biosynthetic process [GO:0009234]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d1sjdb1_d5fjra2__1			Actinobacteria	Actinobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	menaquinone biosynthetic process [GO:0009234]	menaquinone biosynthetic process [GO:0009234]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d1sjdb2_d1tkkd2__1			Actinobacteria	Firmicutes	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	menaquinone biosynthetic process [GO:0009234]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d1sjdc2_d2ggee2__1			Actinobacteria	Firmicutes	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	menaquinone biosynthetic process [GO:0009234]				hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d1sjdc2_d3ttea1__1			Actinobacteria	Proteobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]	menaquinone biosynthetic process [GO:0009234]	cellular amino acid catabolic process [GO:0009063]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]
d1sjdd1_d1chra4__1			Actinobacteria		hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]		menaquinone biosynthetic process [GO:0009234]				hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	
d1sjeb2_d1s7xj2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1sjed2_d2rdha2__1	Metazoa		Chordata	Firmicutes	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	pathogenesis [GO:0009405]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	extracellular region [GO:0005576]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	
d1sjhb1_d3oazk2__1	Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	
d1sjib1_d1usbb2__1	Metazoa	Metazoa	Chordata	Chordata	sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; Z disc [GO:0030018]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	calcium ion binding [GO:0005509]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1sjib2_d2a2sa2__1	Metazoa	Metazoa	Chordata	Chordata	sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1sjma1_d1l9sa2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1sjmb1_d1gs7a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1sjmc1_d4knsd2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1sjmc2_d1ws8c___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1sjna__d2hxea___1			Actinobacteria		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]		dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]				dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	
d1sjna__d3zf6a___1			Actinobacteria		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1sjxa1_d5f9dc1__1				Proteobacteria								
d1sk2a__d2c0ea2__1		Metazoa	Proteobacteria	Arthropoda	arsenate reductase (glutaredoxin) activity [GO:0008794]; response to arsenic-containing substance [GO:0046685]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; protein homodimerization activity [GO:0042803]; dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	response to arsenic-containing substance [GO:0046685]	dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]		endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	arsenate reductase (glutaredoxin) activity [GO:0008794]	protein homodimerization activity [GO:0042803]
d1sk2a__d3l78a___1			Proteobacteria	Firmicutes	arsenate reductase (glutaredoxin) activity [GO:0008794]; response to arsenic-containing substance [GO:0046685]	cytoplasm [GO:0005737]; negative regulation of transcription, DNA-templated [GO:0045892]	response to arsenic-containing substance [GO:0046685]	negative regulation of transcription, DNA-templated [GO:0045892]		cytoplasm [GO:0005737]	arsenate reductase (glutaredoxin) activity [GO:0008794]	
d1sk7a__d1p3va___1			Proteobacteria	Proteobacteria	heme oxygenase (decyclizing) activity [GO:0004392]; heme oxidation [GO:0006788]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	heme oxidation [GO:0006788]	heme oxidation [GO:0006788]			heme oxygenase (decyclizing) activity [GO:0004392]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d1sk8a__d1t8pb___1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; 3-phytase activity [GO:0016158]; acid phosphatase activity [GO:0003993]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	3-phytase activity [GO:0016158]; acid phosphatase activity [GO:0003993]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]
d1skba__d3zhcb___1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; 3-phytase activity [GO:0016158]; acid phosphatase activity [GO:0003993]				extracellular region [GO:0005576]		3-phytase activity [GO:0016158]; acid phosphatase activity [GO:0003993]	
d1skja__d1o4da___1		Metazoa		Chordata	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]		activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]		actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]
d1skma__d1nbic___1		Metazoa	Proteobacteria	Chordata	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	DNA restriction-modification system [GO:0009307]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]		cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d1skma__d5guva3__1		Metazoa	Proteobacteria	Chordata	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	cytoplasm [GO:0005737]; heterochromatin [GO:0000792]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; chromatin binding [GO:0003682]; DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates [GO:0051718]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; methyl-CpG binding [GO:0008327]; methyltransferase activity [GO:0008168]; promoter-specific chromatin binding [GO:1990841]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular response to amino acid stimulus [GO:0071230]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chromatin organization [GO:0006325]; DNA hypermethylation [GO:0044026]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation on cytosine [GO:0032776]; DNA methylation on cytosine within a CG sequence [GO:0010424]; gene silencing [GO:0016458]; maintenance of DNA methylation [GO:0010216]; negative regulation of gene expression [GO:0010629]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular associated smooth muscle cell apoptotic process [GO:1905460]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; response to drug [GO:0042493]; S-adenosylmethionine metabolic process [GO:0046500]	DNA restriction-modification system [GO:0009307]	cellular response to amino acid stimulus [GO:0071230]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chromatin organization [GO:0006325]; DNA hypermethylation [GO:0044026]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation on cytosine [GO:0032776]; DNA methylation on cytosine within a CG sequence [GO:0010424]; gene silencing [GO:0016458]; maintenance of DNA methylation [GO:0010216]; negative regulation of gene expression [GO:0010629]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular associated smooth muscle cell apoptotic process [GO:1905460]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; response to drug [GO:0042493]; S-adenosylmethionine metabolic process [GO:0046500]		cytoplasm [GO:0005737]; heterochromatin [GO:0000792]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	chromatin binding [GO:0003682]; DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates [GO:0051718]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; methyl-CpG binding [GO:0008327]; methyltransferase activity [GO:0008168]; promoter-specific chromatin binding [GO:1990841]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1skqa2_d4pc1b3__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; translation elongation factor activity [GO:0003746]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	translation elongation factor activity [GO:0003746]
d1skqb2_d3agje6__1			Crenarchaeota		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	
d1skrb__d2eirb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1skua2_d3r7db2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1skub1_d2fzcd1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1skuc1_d2otcc2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]
d1skuc2_d9atca1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1skwb__d1n8js___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	thioredoxin peroxidase activity [GO:0008379]
d1skyb3_d4yxwb2__1		Metazoa	Firmicutes	Chordata	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1skye2_d2xokf1__1		Fungi	Firmicutes	Ascomycota	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1skye2_d5hkka1__1			Firmicutes	Firmicutes	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1sl0b__d1ydka2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1sl0c1_d2pyjb1__1			Proteobacteria		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]
d1sl1b__d4oo4b___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d1sl5a__d3g4na1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; toxin activity [GO:0090729]
d1sl5a__d3ikra2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1sl7a__d1b7ty___1	Metazoa	Metazoa	Cnidaria	Mollusca	calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	bioluminescence [GO:0008218]			myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	calcium ion binding [GO:0005509]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]
d1sl7a__d2lvja___1	Metazoa	Viridiplantae	Cnidaria	Streptophyta	calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]	calcium ion binding [GO:0005509]	bioluminescence [GO:0008218]				calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]
d1slaa__d2d7ff___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]; apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]	apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]	extracellular space [GO:0005615]		carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]
d1slab__d2du0a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]; apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	carbohydrate binding [GO:0030246]	apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]		extracellular space [GO:0005615]		carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]	carbohydrate binding [GO:0030246]
d1slba__d3aycb1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]; apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	extracellular space [GO:0005615]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d1slbc__d1uldd___1	Metazoa	Fungi	Chordata	Basidiomycota	extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]; apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]	apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]		extracellular space [GO:0005615]	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]	carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]	carbohydrate binding [GO:0030246]
d1slbd__d5hxvf___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]; apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	xylan catabolic process [GO:0045493]	extracellular space [GO:0005615]		carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]	endo-1,4-beta-xylanase activity [GO:0031176]
d1sleb__d1mepd___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1slfb__d4bbod___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1slgb__d2y32b___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1slha__d4a6aa___1			Actinobacteria	Actinobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d1slhb__d3hhqc___1		Fungi	Actinobacteria	Ascomycota	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1slhc__d5y5qa___1			Actinobacteria		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1slia1_d1a78b___1	Metazoa	Metazoa	Annelida	Chordata	extracellular space [GO:0005615]; anhydrosialidase activity [GO:0033995]; exo-alpha-sialidase activity [GO:0004308]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]	carbohydrate metabolic process [GO:0005975]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	anhydrosialidase activity [GO:0033995]; exo-alpha-sialidase activity [GO:0004308]	carbohydrate binding [GO:0030246]
d1slia2_d2htya___1	Metazoa		Annelida	Negarnaviricota	extracellular space [GO:0005615]; anhydrosialidase activity [GO:0033995]; exo-alpha-sialidase activity [GO:0004308]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	extracellular space [GO:0005615]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	anhydrosialidase activity [GO:0033995]; exo-alpha-sialidase activity [GO:0004308]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1slla1_d4yw2a1__1	Metazoa		Annelida	Firmicutes	extracellular space [GO:0005615]; anhydrosialidase activity [GO:0033995]; exo-alpha-sialidase activity [GO:0004308]; carbohydrate metabolic process [GO:0005975]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]		anhydrosialidase activity [GO:0033995]; exo-alpha-sialidase activity [GO:0004308]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1slma2_d4n66e___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1slna__d1srpa2__1	Metazoa		Chordata	Proteobacteria	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1sm3h1_d1zt4c1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; nuclear chromatin [GO:0000790]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; p53 binding [GO:0002039]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coregulator activity [GO:0003712]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of transcription by competitive promoter binding [GO:0010944]; O-glycan processing [GO:0016266]; positive regulation of histone H4 acetylation [GO:0090240]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of transcription by competitive promoter binding [GO:0010944]; O-glycan processing [GO:0016266]; positive regulation of histone H4 acetylation [GO:0090240]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; nuclear chromatin [GO:0000790]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	p53 binding [GO:0002039]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coregulator activity [GO:0003712]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1sm4a1_d3ozwb2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]		response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1sm4a1_d3w2ha1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]		cholesterol biosynthetic process [GO:0006695]	chloroplast [GO:0009507]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d1sm4b2_d2rc5c2__1	Viridiplantae		Streptophyta	Spirochaetes	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]			chloroplast [GO:0009507]		ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1sm8b1_d4b0hb___1			Actinobacteria	Firmicutes	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1sm9d__d2p5na___1	Fungi	Metazoa	Ascomycota	Chordata	oxidoreductase activity [GO:0016491]; D-xylose catabolic process [GO:0042843]	cytosol [GO:0005829]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	D-xylose catabolic process [GO:0042843]	oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]		cytosol [GO:0005829]	oxidoreductase activity [GO:0016491]	17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]
d1smaa2_d1uktb3__1			Deinococcus-Thermus	Firmicutes	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1smaa2_d3o7zb3__1			Deinococcus-Thermus		alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]	
d1smab2_d6cgta3__1			Deinococcus-Thermus	Firmicutes	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1smca__d5y5pf___1			Actinobacteria		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1smeb__d2avoa___1			Apicomplexa		vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1smfe__d3eajb___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1smga__d5hlva1__1	Metazoa	Metazoa	Chordata	Chordata	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	troponin complex [GO:0005861]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1smja__d4ejga___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d1smjd__d3p3xa___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]			cytoplasm [GO:0005737]		aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1smka1_d5pgvd1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	glyoxysome [GO:0009514]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	L-malate dehydrogenase activity [GO:0030060]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d1smka2_d4nd4b2__1	Viridiplantae		Streptophyta	Apicomplexa	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glyoxysome [GO:0009514]		L-malate dehydrogenase activity [GO:0030060]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d1smkc1_d4l76c1__1	Viridiplantae		Streptophyta	Euryarchaeota	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	potassium ion transport [GO:0006813]	glyoxysome [GO:0009514]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	L-malate dehydrogenase activity [GO:0030060]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1smkd2_d1ldng2__1	Viridiplantae		Streptophyta	Firmicutes	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	glyoxysome [GO:0009514]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1smke1_d3pgxd___1	Viridiplantae		Streptophyta	Actinobacteria	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	oxidoreductase activity [GO:0016491]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		glyoxysome [GO:0009514]		L-malate dehydrogenase activity [GO:0030060]	oxidoreductase activity [GO:0016491]
d1smkf2_d2v7pb2__1	Viridiplantae		Streptophyta	Deinococcus-Thermus	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	glyoxysome [GO:0009514]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d1smoa__d2bnra1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]; acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]	
d1smva__d1ihmb___1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	host cell cytoplasm [GO:0030430]; T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]			viral capsid [GO:0019028]	host cell cytoplasm [GO:0030430]; T=3 icosahedral viral capsid [GO:0039617]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]
d1smvc__d1hxs3___1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1sn0d__d2wqad___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; thyroid hormone binding [GO:0070324]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	extracellular region [GO:0005576]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1snda__d5krua___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1snfa__d4ooqb___1		Viridiplantae	Actinobacteria	Streptophyta	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	cytosol [GO:0005829]; dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]		cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1snfb__d5y5oa___1			Actinobacteria		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1snra1_d4q8bb2__1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	sporulation resulting in formation of a cellular spore [GO:0030435]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1snrb1_d8paza___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1snrc2_d1ehkb1__1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1snrc2_d3zdwa2__1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	sporulation resulting in formation of a cellular spore [GO:0030435]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1snza1_d3i3bd5__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]	beta-galactosidase complex [GO:0009341]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1so0b__d3i3ec5__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]	beta-galactosidase complex [GO:0009341]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1so0c1_d1ns4b1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	galactose metabolic process [GO:0006012]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]		aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1so0d__d1lf9a2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; polysaccharide metabolic process [GO:0005976]	galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	polysaccharide metabolic process [GO:0005976]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]		aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]
d1so3a__d3mwab1__1			Proteobacteria	Apicomplexa	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]			3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1so4b__d1tqxa___1			Proteobacteria	Apicomplexa	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		cytosol [GO:0005829]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d1so6b__d3o05a___1		Fungi	Proteobacteria	Ascomycota	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]		glutaminase complex [GO:1903600]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d1sofa1_d2fg4a___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1sofc__d2jd8f___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d1sofc__d3e1lh___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1soff__d4dyua___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1soga__d4nvda___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1soga__d5aboa1__1	Fungi	Fungi	Ascomycota	Basidiomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]
d1soqb__d2h6ue___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1soqb__d5fw7a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1sosc__d3km2i___1	Metazoa	Viridiplantae	Chordata	Streptophyta	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	chloroplast [GO:0009507]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	removal of superoxide radicals [GO:0019430]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chloroplast [GO:0009507]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]
d1sosg__d1srdb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	chloroplast [GO:0009507]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chloroplast [GO:0009507]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1soua1_d3hn6a1__1			Aquificae	Spirochaetes	5-formyltetrahydrofolate cyclo-ligase activity [GO:0030272]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; folic acid-containing compound biosynthetic process [GO:0009396]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]; glucosamine-6-phosphate deaminase activity [GO:0004342]; carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylneuraminate catabolic process [GO:0019262]	folic acid-containing compound biosynthetic process [GO:0009396]; tetrahydrofolate interconversion [GO:0035999]	carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylneuraminate catabolic process [GO:0019262]		cytosol [GO:0005829]	5-formyltetrahydrofolate cyclo-ligase activity [GO:0030272]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]	glucosamine-6-phosphate deaminase activity [GO:0004342]
d1sovb2_d4zvvc2__1		Metazoa	Apicomplexa	Chordata	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-lactate dehydrogenase activity [GO:0004459]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1sowa1_d1x7ga___1			Apicomplexa	Actinobacteria	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	antibiotic biosynthetic process [GO:0017000]			L-lactate dehydrogenase activity [GO:0004459]	oxidoreductase activity [GO:0016491]
d1sowb1_d1hwze1__1			Apicomplexa		L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]				L-lactate dehydrogenase activity [GO:0004459]	
d1soxb3_d3r18a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]
d1sozb2_d4nwka___1			Proteobacteria		integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1sp4.1_d1w4ta1__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; proteoglycan binding [GO:0043394]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of catalytic activity [GO:0050790]; viral entry into host cell [GO:0046718]	arylamine N-acetyltransferase activity [GO:0004060]	cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of catalytic activity [GO:0050790]; viral entry into host cell [GO:0046718]		extracellular space [GO:0005615]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; proteoglycan binding [GO:0043394]	arylamine N-acetyltransferase activity [GO:0004060]
d1sp4.1_d2auza___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; proteoglycan binding [GO:0043394]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of catalytic activity [GO:0050790]; viral entry into host cell [GO:0046718]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of catalytic activity [GO:0050790]; viral entry into host cell [GO:0046718]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	extracellular space [GO:0005615]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; proteoglycan binding [GO:0043394]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d1sp5a__d3oudb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1sp5a__d5ozya___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1sp5b__d3zpub___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1sp8b1_d1f1vb1__1				Actinobacteria		dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]						dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1spbp__d2boaa2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; histone acetylation [GO:0016573]; proteolysis [GO:0006508]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	histone acetylation [GO:0016573]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1spda__d3gtvl___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1spea__d1b8dk___1	Metazoa		Chordata	Rhodophyta	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1spea__d1y7ga___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1spgb__d2zwja___1	Metazoa	Metazoa	Chordata	Arthropoda	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1sphb__d1pcha___1			Firmicutes	Tenericutes	cytoplasm [GO:0005737]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; regulation of carbohydrate utilization [GO:0043610]	cytoplasm [GO:0005737]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; regulation of carbohydrate utilization [GO:0043610]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]		
d1spsc__d2dlya1__1		Metazoa		Chordata	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral process [GO:0016032]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-tyrosine autophosphorylation [GO:0038083]; regulation of cell population proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	viral process [GO:0016032]	cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-tyrosine autophosphorylation [GO:0038083]; regulation of cell population proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]
d1sq0b__d1xwdc1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; follicle-stimulating hormone receptor activity [GO:0004963]; G protein-coupled peptide receptor activity [GO:0008528]; activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; female gamete generation [GO:0007292]; female gonad development [GO:0008585]; follicle-stimulating hormone signaling pathway [GO:0042699]; G protein-coupled receptor signaling pathway [GO:0007186]; gonad development [GO:0008406]; hormone-mediated signaling pathway [GO:0009755]; male gonad development [GO:0008584]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of protein kinase A signaling [GO:0010738]; spermatogenesis [GO:0007283]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; female gamete generation [GO:0007292]; female gonad development [GO:0008585]; follicle-stimulating hormone signaling pathway [GO:0042699]; gonad development [GO:0008406]; G protein-coupled receptor signaling pathway [GO:0007186]; hormone-mediated signaling pathway [GO:0009755]; male gonad development [GO:0008584]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of protein kinase A signaling [GO:0010738]; spermatogenesis [GO:0007283]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]	follicle-stimulating hormone receptor activity [GO:0004963]; G protein-coupled peptide receptor activity [GO:0008528]
d1sq0b__d3rw7d___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1sq2n__d3gsra2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1sq7b__d1mssa___1	Metazoa		Chordata		cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	triose-phosphate isomerase activity [GO:0004807]
d1sqba1_d3l72b2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1sqca2_d3ksqb___1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1sqld__d1rrwa___1	Viridiplantae		Streptophyta	Firmicutes	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydroneopterin aldolase activity [GO:0004150]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]
d1sqle__d1a8rc___1	Viridiplantae		Streptophyta	Proteobacteria	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	dihydroneopterin aldolase activity [GO:0004150]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1sqli__d4d17a2__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytosol [GO:0005829]	peroxisome [GO:0005777]	dihydroneopterin aldolase activity [GO:0004150]	urate oxidase activity [GO:0004846]
d1sqlj__d1fb1a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; cofactor metabolic process [GO:0051186]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of heart rate [GO:0010460]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; neuron projection terminus [GO:0044306]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	dihydroneopterin aldolase activity [GO:0004150]	calcium ion binding [GO:0005509]; coenzyme binding [GO:0050662]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; GTP-dependent protein binding [GO:0030742]; mitogen-activated protein kinase binding [GO:0051019]; protein homodimerization activity [GO:0042803]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]
d1sqlk__d4r99d1__1	Viridiplantae		Streptophyta	Firmicutes	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]		folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]		dihydroneopterin aldolase activity [GO:0004150]	
d1sqll__d3pkga2__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytosol [GO:0005829]	peroxisome [GO:0005777]	dihydroneopterin aldolase activity [GO:0004150]	urate oxidase activity [GO:0004846]
d1sqlm__d1b9lg___1	Viridiplantae		Streptophyta	Proteobacteria	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]; folic acid-containing compound metabolic process [GO:0006760]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]	cytosol [GO:0005829]	cytosol [GO:0005829]	dihydroneopterin aldolase activity [GO:0004150]	dihydroneopterin aldolase activity [GO:0004150]; dihydroneopterin triphosphate 2'-epimerase activity [GO:0008719]
d1sqln__d1is7h___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	dihydroneopterin aldolase activity [GO:0004150]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]
d1sqlo__d1vaxg1__1	Viridiplantae		Streptophyta		cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]		folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]		dihydroneopterin aldolase activity [GO:0004150]	
d1sqlp__d3l9ga2__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytosol [GO:0005829]	peroxisome [GO:0005777]	dihydroneopterin aldolase activity [GO:0004150]	urate oxidase activity [GO:0004846]
d1sqpa1_d3l73b1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1sqpb2_d3l73a2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1sqqa1_d1hr9d1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]; aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]
d1sqqb1_d1kyoa1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1sqqb1_d3l74o1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1sqqb2_d1sqpb1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1sqqb2_d3l75a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1sqqd1_d3h1hd1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1sqta__d3gy6a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	digestion [GO:0007586]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1sqva1_d3h1ja1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1sqwa1_d1it8a3__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; preribosome, large subunit precursor [GO:0030687]; RNA binding [GO:0003723]; ribosomal large subunit biogenesis [GO:0042273]; ribosome assembly [GO:0042255]	metal ion binding [GO:0046872]; RNA binding [GO:0003723]; transferase activity, transferring pentosyl groups [GO:0016763]; tRNA modification [GO:0006400]	ribosomal large subunit biogenesis [GO:0042273]; ribosome assembly [GO:0042255]	tRNA modification [GO:0006400]	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; preribosome, large subunit precursor [GO:0030687]		RNA binding [GO:0003723]	metal ion binding [GO:0046872]; RNA binding [GO:0003723]; transferase activity, transferring pentosyl groups [GO:0016763]
d1sqwa2_d1iq8a4__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; preribosome, large subunit precursor [GO:0030687]; RNA binding [GO:0003723]; ribosomal large subunit biogenesis [GO:0042273]; ribosome assembly [GO:0042255]	metal ion binding [GO:0046872]; RNA binding [GO:0003723]; transferase activity, transferring pentosyl groups [GO:0016763]; tRNA modification [GO:0006400]	ribosomal large subunit biogenesis [GO:0042273]; ribosome assembly [GO:0042255]	tRNA modification [GO:0006400]	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; preribosome, large subunit precursor [GO:0030687]		RNA binding [GO:0003723]	metal ion binding [GO:0046872]; RNA binding [GO:0003723]; transferase activity, transferring pentosyl groups [GO:0016763]
d1sqxa1_d1hr6d1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1sqxa2_d1hr7f2__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1sqxe2_d4aayb___1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]
d1sqya1_d1ieja___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]
d1sqya2_d4iy5b1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1sr4c__d1rzob2__1		Viridiplantae	Proteobacteria	Streptophyta	pathogenesis [GO:0009405]	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	pathogenesis [GO:0009405]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]		endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1sr5.1_d1fy4a___1	Metazoa	Fungi	Chordata	Ascomycota	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	serine-type endopeptidase activity [GO:0004252]
d1sr6b__d3ko0d___1	Metazoa	Metazoa	Mollusca	Chordata	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]		epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d1sr6b__d5t0xa___1	Metazoa	Metazoa	Mollusca	Chordata	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]		calcium-mediated signaling [GO:0019722]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]		actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]
d1sraa__d2k61a___1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; nuclear matrix [GO:0016363]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; platelet alpha granule membrane [GO:0031092]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; extracellular matrix binding [GO:0050840]; bone development [GO:0060348]; cellular response to growth factor stimulus [GO:0071363]; extracellular matrix organization [GO:0030198]; heart development [GO:0007507]; inner ear development [GO:0048839]; lung development [GO:0030324]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; ossification [GO:0001503]; pigmentation [GO:0043473]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; receptor-mediated endocytosis [GO:0006898]; regulation of cell morphogenesis [GO:0022604]; regulation of synapse organization [GO:0050807]; response to cadmium ion [GO:0046686]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to gravity [GO:0009629]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; wound healing [GO:0042060]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	bone development [GO:0060348]; cellular response to growth factor stimulus [GO:0071363]; extracellular matrix organization [GO:0030198]; heart development [GO:0007507]; inner ear development [GO:0048839]; lung development [GO:0030324]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; ossification [GO:0001503]; pigmentation [GO:0043473]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; receptor-mediated endocytosis [GO:0006898]; regulation of cell morphogenesis [GO:0022604]; regulation of synapse organization [GO:0050807]; response to cadmium ion [GO:0046686]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to gravity [GO:0009629]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; wound healing [GO:0042060]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	basement membrane [GO:0005604]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; nuclear matrix [GO:0016363]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; platelet alpha granule membrane [GO:0031092]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; extracellular matrix binding [GO:0050840]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d1srib__d4z2vb___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]
d1sroa__d1eqqa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; 3'-5'-exoribonuclease activity [GO:0000175]; cyclic-di-GMP binding [GO:0035438]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; polyribonucleotide nucleotidyltransferase activity [GO:0004654]; RNA binding [GO:0003723]; mRNA catabolic process [GO:0006402]; response to heat [GO:0009408]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytosol [GO:0005829]; enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]	mRNA catabolic process [GO:0006402]; response to heat [GO:0009408]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	3'-5'-exoribonuclease activity [GO:0000175]; cyclic-di-GMP binding [GO:0035438]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; polyribonucleotide nucleotidyltransferase activity [GO:0004654]; RNA binding [GO:0003723]	enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]
d1srra__d2r25b___1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]; osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	kinase activity [GO:0016301]; metal ion binding [GO:0046872]	histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]
d1srva__d1xcki3__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]		'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	ATP binding [GO:0005524]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]
d1ssga__d2j27b___1	Metazoa		Chordata		cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	triose-phosphate isomerase activity [GO:0004807]
d1ssqa__d4n69b___1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]	cytosol [GO:0005829]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]	cytosol [GO:0005829]	cytosol [GO:0005829]	serine O-acetyltransferase activity [GO:0009001]	serine O-acetyltransferase activity [GO:0009001]
d1st0a1_d1xmmd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]; cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]; cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]	exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]
d1st4a1_d1kpea___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]; cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d1st4a1_d3blaa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]; cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]; cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]	exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]
d1st6a4_d3vf0a___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell junction [GO:0005911]; costamere [GO:0043034]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; mitochondrial inner membrane [GO:0005743]; muscle tendon junction [GO:0005927]; neuromuscular junction [GO:0031594]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; terminal web [GO:1990357]; Z disc [GO:0030018]; zonula adherens [GO:0005915]; actin filament binding [GO:0051015]; alpha-actinin binding [GO:0051393]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; muscle alpha-actinin binding [GO:0051371]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]; vinculin binding [GO:0017166]; adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; protein localization to cell surface [GO:0034394]; regulation of cell migration [GO:0030334]	adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; membrane raft [GO:0045121]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; terminal web [GO:1990357]; zonula adherens [GO:0005915]; actin binding [GO:0003779]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]; adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; muscle contraction [GO:0006936]; negative regulation of cell migration [GO:0030336]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; protein localization to cell surface [GO:0034394]	adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; protein localization to cell surface [GO:0034394]; regulation of cell migration [GO:0030334]	adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; muscle contraction [GO:0006936]; negative regulation of cell migration [GO:0030336]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; protein localization to cell surface [GO:0034394]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell junction [GO:0005911]; costamere [GO:0043034]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; mitochondrial inner membrane [GO:0005743]; muscle tendon junction [GO:0005927]; neuromuscular junction [GO:0031594]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; terminal web [GO:1990357]; Z disc [GO:0030018]; zonula adherens [GO:0005915]	adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; membrane raft [GO:0045121]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; terminal web [GO:1990357]; zonula adherens [GO:0005915]	actin filament binding [GO:0051015]; alpha-actinin binding [GO:0051393]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; muscle alpha-actinin binding [GO:0051371]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]; vinculin binding [GO:0017166]	actin binding [GO:0003779]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]
d1st9a__d4q5fd1__1		Metazoa	Firmicutes	Nematoda (roundworms)	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	brush border [GO:0005903]; cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; cellular oxidant detoxification [GO:0098869]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cellular oxidant detoxification [GO:0098869]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	brush border [GO:0005903]; cytoplasm [GO:0005737]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]
d1st9b__d3vi7b1__1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1staa__d4yija___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1stda__d5aewf___1	Fungi		Ascomycota	Proteobacteria	endosome [GO:0005768]; metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]; melanin biosynthetic process [GO:0042438]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	melanin biosynthetic process [GO:0042438]	aromatic compound catabolic process [GO:0019439]	endosome [GO:0005768]		metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1stga__d3v2ta___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1stma__d1vtzg___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]	
d1stmc__d2buka___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1stmd__d4bcua___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1stqa__d5cidc___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1strd__d3t2xb___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1su1a__d1s3nb___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; phosphoric diester hydrolase activity [GO:0008081]; protein homotetramerization [GO:0051289]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	protein homotetramerization [GO:0051289]		cytosol [GO:0005829]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; phosphoric diester hydrolase activity [GO:0008081]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1su1b__d4dsyc2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; phosphoric diester hydrolase activity [GO:0008081]; protein homotetramerization [GO:0051289]	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	protein homotetramerization [GO:0051289]		cytosol [GO:0005829]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; phosphoric diester hydrolase activity [GO:0008081]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]
d1su1c__d2nylc1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; phosphoric diester hydrolase activity [GO:0008081]; protein homotetramerization [GO:0051289]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	protein homotetramerization [GO:0051289]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	cytosol [GO:0005829]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; phosphoric diester hydrolase activity [GO:0008081]	GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]
d1su2a__d1nfza___1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; hydrolase activity [GO:0016787]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]		cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; hydrolase activity [GO:0016787]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]
d1su2b__d3q93a___1		Metazoa	Deinococcus-Thermus	Chordata	ATP binding [GO:0005524]; hydrolase activity [GO:0016787]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTP diphosphatase activity [GO:0036219]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]; aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; hydrolase activity [GO:0016787]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTPase activity [GO:0003924]; GTP diphosphatase activity [GO:0036219]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]
d1su3a2_d4fvla2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1su3a3_d3lk8a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1su3b3_d1os2b1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1su5b__d4bi5b___1	Metazoa		Chordata		cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]
d1su9a__d4xtsn___1			Firmicutes	Proteobacteria	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]	thioredoxin peroxidase activity [GO:0008379]
d1su9b__d1yf1a1__1			Firmicutes	Proteobacteria	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]	thioredoxin peroxidase activity [GO:0008379]
d1suia1_d3c3yb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]; lignin biosynthetic process [GO:0009809]	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]	lignin biosynthetic process [GO:0009809]				caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]
d1suib__d5cvvb2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]; lignin biosynthetic process [GO:0009809]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]	lignin biosynthetic process [GO:0009809]				caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]
d1suja1_d3vgfa1__1	Metazoa		Chordata	Crenarchaeota	signal transduction [GO:0007165]	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	signal transduction [GO:0007165]	trehalose biosynthetic process [GO:0005992]		cytoplasm [GO:0005737]		4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]
d1sulb__d4asub2__1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; division septum assembly [GO:0000917]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	division septum assembly [GO:0000917]	ATP synthesis coupled proton transport [GO:0015986]	cytosol [GO:0005829]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1suoa1_d3tikb1__1	Metazoa		Chordata		endoplasmic reticulum membrane [GO:0005789]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	endoplasmic reticulum membrane [GO:0005789]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d1sura__d1ee1a___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; phosphoadenylyl-sulfate reductase (thioredoxin) activity [GO:0004604]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur compound metabolic process [GO:0006790]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]; NAD biosynthetic process [GO:0009435]; sporulation resulting in formation of a cellular spore [GO:0030435]	hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur compound metabolic process [GO:0006790]	NAD biosynthetic process [GO:0009435]; sporulation resulting in formation of a cellular spore [GO:0030435]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	phosphoadenylyl-sulfate reductase (thioredoxin) activity [GO:0004604]	ATP binding [GO:0005524]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]
d1susa__d5kvaa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]; lignin biosynthetic process [GO:0009809]	metal ion binding [GO:0046872]; O-methyltransferase activity [GO:0008171]	lignin biosynthetic process [GO:0009809]				caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; O-methyltransferase activity [GO:0008171]
d1susb__d2c7qa___1	Viridiplantae		Streptophyta	Proteobacteria	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]; lignin biosynthetic process [GO:0009809]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	lignin biosynthetic process [GO:0009809]	DNA restriction-modification system [GO:0009307]			caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d1susc__d5cuqa___1	Viridiplantae		Streptophyta		caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]; lignin biosynthetic process [GO:0009809]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	lignin biosynthetic process [GO:0009809]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1susd__d1kywc2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]; lignin biosynthetic process [GO:0009809]	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]; lignin biosynthetic process [GO:0009809]	lignin biosynthetic process [GO:0009809]	lignin biosynthetic process [GO:0009809]			caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]
d1suxb__d2yc8h___1					glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		glycosome [GO:0020015]		triose-phosphate isomerase activity [GO:0004807]	
d1sv0b1_d2qara___1	Metazoa		Arthropoda		nucleus [GO:0005634]; activating transcription factor binding [GO:0033613]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; repressing transcription factor binding [GO:0070491]; sequence-specific DNA binding [GO:0043565]; cell differentiation [GO:0030154]; embryonic pattern specification [GO:0009880]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nuclear export [GO:0051168]; photoreceptor cell development [GO:0042461]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of phosphorylation [GO:0042325]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory organ development [GO:0007423]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell differentiation [GO:0030154]; embryonic pattern specification [GO:0009880]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nuclear export [GO:0051168]; photoreceptor cell development [GO:0042461]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of phosphorylation [GO:0042325]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory organ development [GO:0007423]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	nucleus [GO:0005634]	host cell cytoplasm [GO:0030430]	activating transcription factor binding [GO:0033613]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; repressing transcription factor binding [GO:0070491]; sequence-specific DNA binding [GO:0043565]	lysozyme activity [GO:0003796]
d1sv0c1_d1sv0a1__1	Metazoa	Metazoa	Arthropoda	Arthropoda	nucleus [GO:0005634]; activating transcription factor binding [GO:0033613]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; repressing transcription factor binding [GO:0070491]; sequence-specific DNA binding [GO:0043565]; cell differentiation [GO:0030154]; embryonic pattern specification [GO:0009880]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nuclear export [GO:0051168]; photoreceptor cell development [GO:0042461]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of phosphorylation [GO:0042325]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory organ development [GO:0007423]	nucleus [GO:0005634]; activating transcription factor binding [GO:0033613]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; repressing transcription factor binding [GO:0070491]; sequence-specific DNA binding [GO:0043565]; cell differentiation [GO:0030154]; embryonic pattern specification [GO:0009880]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nuclear export [GO:0051168]; photoreceptor cell development [GO:0042461]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of phosphorylation [GO:0042325]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory organ development [GO:0007423]	cell differentiation [GO:0030154]; embryonic pattern specification [GO:0009880]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nuclear export [GO:0051168]; photoreceptor cell development [GO:0042461]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of phosphorylation [GO:0042325]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory organ development [GO:0007423]	cell differentiation [GO:0030154]; embryonic pattern specification [GO:0009880]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nuclear export [GO:0051168]; photoreceptor cell development [GO:0042461]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of phosphorylation [GO:0042325]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory organ development [GO:0007423]	nucleus [GO:0005634]	nucleus [GO:0005634]	activating transcription factor binding [GO:0033613]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; repressing transcription factor binding [GO:0070491]; sequence-specific DNA binding [GO:0043565]	activating transcription factor binding [GO:0033613]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; repressing transcription factor binding [GO:0070491]; sequence-specific DNA binding [GO:0043565]
d1sv6a__d1qcob2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; 2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]; arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	cytoplasm [GO:0005737]		2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]
d1sva2__d1sieb___1					capsomere [GO:0046727]; host cell endoplasmic reticulum [GO:0044165]; host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; protein homooligomerization [GO:0051260]; viral capsid assembly [GO:0019069]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; protein homooligomerization [GO:0051260]; viral capsid assembly [GO:0019069]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]	capsomere [GO:0046727]; host cell endoplasmic reticulum [GO:0044165]; host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]	host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1svcp2_d4lo9d___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1svda2_d1rcxr2__1		Viridiplantae	Proteobacteria	Streptophyta	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1svmb__d1g9xb___1				Euryarchaeota	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; amino acid transport [GO:0006865]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	amino acid transport [GO:0006865]	host cell nucleus [GO:0042025]	plasma membrane [GO:0005886]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]
d1svmd__d3cf1b2__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	host cell nucleus [GO:0042025]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1svoa__d4ymtj___1				Firmicutes	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; nitrogen compound transport [GO:0071705]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	nitrogen compound transport [GO:0071705]	host cell nucleus [GO:0042025]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]	transmembrane transporter activity [GO:0022857]
d1svra__d2fh2b3__1		Metazoa		Chordata	actin cytoskeleton [GO:0015629]; phagocytic vesicle [GO:0045335]; actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; actin filament capping [GO:0051693]; actin filament fragmentation [GO:0030043]; actin filament severing [GO:0051014]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament fragmentation [GO:0030043]; actin filament severing [GO:0051014]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cytoskeleton [GO:0015629]; phagocytic vesicle [GO:0045335]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1svtb3_d1aona2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d1svtf3_d1we3e2__1			Proteobacteria		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	
d1svth3_d1q3sg2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1svti3_d1q3sd2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1svtt__d4pj1y___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; chaperone cofactor-dependent protein refolding [GO:0051085]; osteoblast differentiation [GO:0001649]; protein folding [GO:0006457]; response to unfolded protein [GO:0006986]	cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; chaperone cofactor-dependent protein refolding [GO:0051085]; osteoblast differentiation [GO:0001649]; protein folding [GO:0006457]; response to unfolded protein [GO:0006986]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]
d1svza1_d3kwwb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1svza2_d3wihm1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]	axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]
d1sw2a__d3ho7a1__1			Euryarchaeota	Bacteroidetes	ATP-binding cassette (ABC) transporter complex [GO:0043190]; metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]			ATP-binding cassette (ABC) transporter complex [GO:0043190]		metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1sw3b__d4o4va___1	Metazoa		Chordata		cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytosol [GO:0005829]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	triose-phosphate isomerase activity [GO:0004807]
d1sw4b__d1lfia2__1		Metazoa	Euryarchaeota	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]		antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d1sw5a__d2qs2a___1		Metazoa	Euryarchaeota	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d1sw5d__d3k6wa___1			Euryarchaeota	Euryarchaeota	ATP-binding cassette (ABC) transporter complex [GO:0043190]; metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]	outer membrane-bounded periplasmic space [GO:0030288]; tungstate binding [GO:1901359]			ATP-binding cassette (ABC) transporter complex [GO:0043190]	outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]	tungstate binding [GO:1901359]
d1sw8a__d1l2ob___1	Metazoa	Metazoa	Chordata	Mollusca	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]
d1sw8a__d4phma___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d1swcb__d4ggtb___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1swec__d4bj8f___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1swgc__d1swoa___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1swjc__d1kffb___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1swkb__d2izhd___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1swkd__d1stsd___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1swra__d3wypa___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1swrc__d2f01a___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1swtb__d4bj8p___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1swva__d1rdfb___1			Firmicutes	Firmicutes	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	organic phosphonate catabolic process [GO:0019700]	organic phosphonate catabolic process [GO:0019700]			magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]
d1swva__d3hlta1__1		Metazoa	Firmicutes	Chordata	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	extracellular exosome [GO:0070062]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; dephosphorylation [GO:0016311]	organic phosphonate catabolic process [GO:0019700]	dephosphorylation [GO:0016311]		extracellular exosome [GO:0070062]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]
d1swwa__d2r8ef___1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	organic phosphonate catabolic process [GO:0019700]	lipopolysaccharide biosynthetic process [GO:0009103]			magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1sx4p__d1jh2g___1			Proteobacteria		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	
d1sxaa__d2zkyb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1sxba__d5k02g___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1sxea1_d1lkyc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription by RNA polymerase II [GO:0006357]; vitellogenesis [GO:0007296]	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]	cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription by RNA polymerase II [GO:0006357]; vitellogenesis [GO:0007296]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d1sxgf__d4rkqa1__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1sxgp__d4yr7a___1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	periplasmic space [GO:0042597]	regulation of transcription, DNA-templated [GO:0006355]			periplasmic space [GO:0042597]	DNA binding [GO:0003677]	
d1sxjb2_d1ki9b___1	Fungi		Ascomycota	Euryarchaeota	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]		chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]
d1sxje1_d1jr3b1__1	Fungi		Ascomycota	Proteobacteria	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA-dependent DNA replication [GO:0006261]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1sxla__d1g2ea2__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; poly(U) RNA binding [GO:0008266]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; alternative mRNA splicing, via spliceosome [GO:0000380]; dosage compensation [GO:0007549]; epithelium regeneration [GO:1990399]; female sex determination [GO:0030237]; imaginal disc growth [GO:0007446]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of translation [GO:0017148]; oocyte differentiation [GO:0009994]; oogenesis [GO:0048477]; positive regulation of RNA splicing [GO:0033120]; positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; reciprocal meiotic recombination [GO:0007131]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of stem cell division [GO:2000035]; sex determination [GO:0007530]; sex determination, primary response to X:A ratio [GO:0007541]; sex differentiation [GO:0007548]; somatic sex determination [GO:0018993]	cytoplasm [GO:0005737]; dendrite [GO:0030425]; growth cone [GO:0030426]; perikaryon [GO:0043204]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	alternative mRNA splicing, via spliceosome [GO:0000380]; dosage compensation [GO:0007549]; epithelium regeneration [GO:1990399]; female sex determination [GO:0030237]; imaginal disc growth [GO:0007446]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of translation [GO:0017148]; oocyte differentiation [GO:0009994]; oogenesis [GO:0048477]; positive regulation of RNA splicing [GO:0033120]; positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; reciprocal meiotic recombination [GO:0007131]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of stem cell division [GO:2000035]; sex determination [GO:0007530]; sex determination, primary response to X:A ratio [GO:0007541]; sex differentiation [GO:0007548]; somatic sex determination [GO:0018993]	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; dendrite [GO:0030425]; growth cone [GO:0030426]; perikaryon [GO:0043204]; ribonucleoprotein complex [GO:1990904]	mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; poly(U) RNA binding [GO:0008266]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]
d1sxla__d2kxha1__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; poly(U) RNA binding [GO:0008266]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; alternative mRNA splicing, via spliceosome [GO:0000380]; dosage compensation [GO:0007549]; epithelium regeneration [GO:1990399]; female sex determination [GO:0030237]; imaginal disc growth [GO:0007446]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of translation [GO:0017148]; oocyte differentiation [GO:0009994]; oogenesis [GO:0048477]; positive regulation of RNA splicing [GO:0033120]; positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; reciprocal meiotic recombination [GO:0007131]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of stem cell division [GO:2000035]; sex determination [GO:0007530]; sex determination, primary response to X:A ratio [GO:0007541]; sex differentiation [GO:0007548]; somatic sex determination [GO:0018993]	cell junction [GO:0030054]; nucleoplasm [GO:0005654]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]	alternative mRNA splicing, via spliceosome [GO:0000380]; dosage compensation [GO:0007549]; epithelium regeneration [GO:1990399]; female sex determination [GO:0030237]; imaginal disc growth [GO:0007446]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of translation [GO:0017148]; oocyte differentiation [GO:0009994]; oogenesis [GO:0048477]; positive regulation of RNA splicing [GO:0033120]; positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; reciprocal meiotic recombination [GO:0007131]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of stem cell division [GO:2000035]; sex determination [GO:0007530]; sex determination, primary response to X:A ratio [GO:0007541]; sex differentiation [GO:0007548]; somatic sex determination [GO:0018993]	apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]	cell junction [GO:0030054]; nucleoplasm [GO:0005654]	mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; poly(U) RNA binding [GO:0008266]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d1sxsa__d5u9mb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1sxua__d5xn9b1__1	Metazoa	Metazoa	Arthropoda	Tardigrada (water bears)	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	extracellular region [GO:0005576]; lipid binding [GO:0008289]	vasodilation [GO:0042311]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	lipid binding [GO:0008289]
d1sxwa__d5kida___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	vasodilation [GO:0042311]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1sxxa__d1np1a___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	vasodilation [GO:0042311]	vasodilation [GO:0042311]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]
d1sxya__d3p6ha1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	vasodilation [GO:0042311]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1sxza__d1n19b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1sxzb__d2e47b___1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]		chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1sy0a__d4qypc___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	vasodilation [GO:0042311]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1sy3a__d5dg4c___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	vasodilation [GO:0042311]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1sy6h1_d1s5il1__1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1sy6h2_d3b9ke___1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]	coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]
d1sy6h2_d3bkjh1__1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1sy6l2_d4odxl___1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; monomeric IgA immunoglobulin complex [GO:0071748]; pentameric IgM immunoglobulin complex [GO:0071756]; plasma membrane [GO:0005886]; secretory IgA immunoglobulin complex [GO:0071751]; antigen binding [GO:0003823]; antibacterial humoral response [GO:0019731]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antibacterial humoral response [GO:0019731]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; monomeric IgA immunoglobulin complex [GO:0071748]; pentameric IgM immunoglobulin complex [GO:0071756]; plasma membrane [GO:0005886]; secretory IgA immunoglobulin complex [GO:0071751]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]	antigen binding [GO:0003823]
d1sy9a1_d1kful1__1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	calcium-mediated signaling [GO:0019722]	cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d1syea__d1snoa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1syfa__d4pmca___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1syia__d2cexb___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d1syia__d2rc9b___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; NMDA selective glutamate receptor complex [GO:0017146]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; glutamate receptor activity [GO:0008066]; glycine binding [GO:0016594]; ionotropic glutamate receptor activity [GO:0004970]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; protein phosphatase 2A binding [GO:0051721]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; calcium ion transport [GO:0006816]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; rhythmic process [GO:0048511]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	calcium ion transport [GO:0006816]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; rhythmic process [GO:0048511]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; NMDA selective glutamate receptor complex [GO:0017146]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	glutamate receptor activity [GO:0008066]; glycine binding [GO:0016594]; ionotropic glutamate receptor activity [GO:0004970]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; protein phosphatase 2A binding [GO:0051721]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1syla__d4apzx___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1synb__d5x5qd___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1syrd__d4mzca___1			Apicomplexa	Apicomplexa	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; antioxidant activity [GO:0016209]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase (glutathione) activity [GO:0019153]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]	protein disulfide oxidoreductase activity [GO:0015035]	antioxidant activity [GO:0016209]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase (glutathione) activity [GO:0019153]
d1syrg__d1ktea___1		Metazoa	Apicomplexa	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]	protein disulfide oxidoreductase activity [GO:0015035]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d1syrg__d2vcvn1__1		Metazoa	Apicomplexa	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	protein disulfide oxidoreductase activity [GO:0015035]	glutathione transferase activity [GO:0004364]
d1syri__d1gsdd2__1		Metazoa	Apicomplexa	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	protein disulfide oxidoreductase activity [GO:0015035]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1syri__d2vm1a___1		Viridiplantae	Apicomplexa	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]	protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d1syrk__d2mmna1__1			Apicomplexa	Apicomplexa	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]	protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d1syrl__d8gssa2__1		Metazoa	Apicomplexa	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	protein disulfide oxidoreductase activity [GO:0015035]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1sysa2_d1a6zc2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1sysb__d1fgnl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1sysb__d2dwdb2__1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	voltage-gated potassium channel complex [GO:0008076]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1syva2_d4pjga1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1syvb__d4ezma2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d1syxa__d1gsua2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]	glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d1sz6a__d4q9fa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1sz6b1_d3ca4a1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1sz6b2_d3cefb2__1	Viridiplantae		Streptophyta		carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]				carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	
d1sz6b2_d4zfub1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1szac1_d3d9ia1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA polymerase II complex binding [GO:0000993]; mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; termination of RNA polymerase II transcription [GO:0006369]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; termination of RNA polymerase II transcription, poly(A)-coupled [GO:0030846]	cytoplasm [GO:0005737]; mRNA cleavage factor complex [GO:0005849]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA polymerase core enzyme binding [GO:0043175]; RNA polymerase II C-terminal domain phosphoserine binding [GO:1990269]; RNA polymerase II complex binding [GO:0000993]; mRNA polyadenylation [GO:0006378]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; termination of RNA polymerase II transcription [GO:0006369]	mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; termination of RNA polymerase II transcription [GO:0006369]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; termination of RNA polymerase II transcription, poly(A)-coupled [GO:0030846]	mRNA polyadenylation [GO:0006378]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; termination of RNA polymerase II transcription [GO:0006369]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; mRNA cleavage factor complex [GO:0005849]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA binding [GO:0003729]; RNA polymerase II complex binding [GO:0000993]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA polymerase core enzyme binding [GO:0043175]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II C-terminal domain phosphoserine binding [GO:1990269]
d1szhb__d1szha1__1	Metazoa	Metazoa	Nematoda (roundworms)	Nematoda (roundworms)	extracellular region [GO:0005576]; signaling receptor binding [GO:0005102]; male sex determination [GO:0030238]	extracellular region [GO:0005576]; signaling receptor binding [GO:0005102]; male sex determination [GO:0030238]	male sex determination [GO:0030238]	male sex determination [GO:0030238]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	signaling receptor binding [GO:0005102]	signaling receptor binding [GO:0005102]
d1szjg2_d2pkro2__1	Metazoa	Viridiplantae	Arthropoda	Streptophyta	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1szkc__d2w7fa___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]
d1szkd__d4jf1b___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	cytoplasm [GO:0005737]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinyldiaminopimelate transaminase activity [GO:0009016]; arginine biosynthetic process [GO:0006526]; lysine biosynthetic process via diaminopimelate [GO:0009089]	arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	arginine biosynthetic process [GO:0006526]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinyldiaminopimelate transaminase activity [GO:0009016]
d1szna1_d1kbba1__1	Fungi	Metazoa	Ascomycota	Chordata	alpha-galactosidase activity [GO:0004557]; raffinose alpha-galactosidase activity [GO:0052692]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-galactosidase activity [GO:0004557]; raffinose alpha-galactosidase activity [GO:0052692]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1szna1_d4howa2__1	Fungi		Ascomycota	Proteobacteria	alpha-galactosidase activity [GO:0004557]; raffinose alpha-galactosidase activity [GO:0052692]; carbohydrate metabolic process [GO:0005975]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			alpha-galactosidase activity [GO:0004557]; raffinose alpha-galactosidase activity [GO:0052692]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d1szna2_d3amcb___1	Fungi		Ascomycota	Thermotogae	alpha-galactosidase activity [GO:0004557]; raffinose alpha-galactosidase activity [GO:0052692]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]		extracellular region [GO:0005576]	alpha-galactosidase activity [GO:0004557]; raffinose alpha-galactosidase activity [GO:0052692]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1szob__d1wdma4__1			Actinobacteria	Proteobacteria	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation multienzyme complex [GO:0036125]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d1szod__d1x0ua1__1			Actinobacteria	Crenarchaeota	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; propionyl-CoA carboxylase activity [GO:0004658]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		acetyl-CoA carboxylase complex [GO:0009317]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	acetyl-CoA carboxylase activity [GO:0003989]; propionyl-CoA carboxylase activity [GO:0004658]
d1szoh__d5jbxb1__1			Actinobacteria	Proteobacteria	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	3-hydroxybutyryl-CoA dehydratase activity [GO:0003859]					hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	3-hydroxybutyryl-CoA dehydratase activity [GO:0003859]
d1szoj__d3ktjd___1			Actinobacteria	Firmicutes	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]
d1szok__d1dcic___1		Metazoa	Actinobacteria	Chordata	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	mitochondrion [GO:0005739]; peroxisome [GO:0005777]; delta3,5-delta2,4-dienoyl-CoA isomerase activity [GO:0051750]; fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation [GO:0006635]		mitochondrion [GO:0005739]; peroxisome [GO:0005777]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	delta3,5-delta2,4-dienoyl-CoA isomerase activity [GO:0051750]
d1szsb__d4y0ia___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	cytosol [GO:0005829]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]	(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]
d1szsc__d2vlfb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	tyrosine metabolic process [GO:0006570]	cytosol [GO:0005829]		4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]	tyrosine phenol-lyase activity [GO:0050371]
d1szsd__d1b5pb___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	cytoplasm [GO:0005737]; aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]	aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]
d1szub__d2dgkc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]
d1szxb1_d2a03a1__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	
d1t03h2_d1nkra1__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; immune response [GO:0006955]; natural killer cell inhibitory signaling pathway [GO:0002769]; regulation of immune response [GO:0050776]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	immune response [GO:0006955]; natural killer cell inhibitory signaling pathway [GO:0002769]; regulation of immune response [GO:0050776]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	signaling receptor activity [GO:0038023]
d1t03h2_d3p4ne___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1t03l2_d1igcl1__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d1t04a1_d5dd1l1__1												
d1t04c1_d1f4yh1__1												
d1t04d2_d3ks0l2__1		Fungi		Ascomycota		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]		lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]		heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]
d1t09a__d1qztb___1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; 2-oxoglutarate metabolic process [GO:0006103]; female gonad development [GO:0008585]; glutathione metabolic process [GO:0006749]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; NADPH regeneration [GO:0006740]; neutrophil degranulation [GO:0043312]; protein targeting to peroxisome [GO:0006625]; regulation of phospholipid biosynthetic process [GO:0071071]; regulation of phospholipid catabolic process [GO:0060696]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; tricarboxylic acid cycle [GO:0006099]	plasma membrane [GO:0005886]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	2-oxoglutarate metabolic process [GO:0006103]; female gonad development [GO:0008585]; glutathione metabolic process [GO:0006749]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADPH regeneration [GO:0006740]; NADP metabolic process [GO:0006739]; neutrophil degranulation [GO:0043312]; protein targeting to peroxisome [GO:0006625]; regulation of phospholipid biosynthetic process [GO:0071071]; regulation of phospholipid catabolic process [GO:0060696]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; tricarboxylic acid cycle [GO:0006099]	acetyl-CoA biosynthetic process [GO:0006085]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]	phosphate acetyltransferase activity [GO:0008959]
d1t0ba__d1iphb1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]		cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	metal ion binding [GO:0046872]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1t0bb__d4l8yc___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	vacuole [GO:0005773]; gamma-glutamyl-peptidase activity [GO:0034722]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]		folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]		vacuole [GO:0005773]	metal ion binding [GO:0046872]	gamma-glutamyl-peptidase activity [GO:0034722]
d1t0bg__d4ofwc2__1		Viridiplantae	Firmicutes	Streptophyta	metal ion binding [GO:0046872]	cytosol [GO:0005829]; glyoxalase III activity [GO:0019172]; lactoylglutathione lyase activity [GO:0004462]				cytosol [GO:0005829]	metal ion binding [GO:0046872]	glyoxalase III activity [GO:0019172]; lactoylglutathione lyase activity [GO:0004462]
d1t0fa2_d4zi0a1__1			Proteobacteria	Negarnaviricota	cytoplasmic chromosome [GO:0000229]; DNA binding [GO:0003677]; nuclease activity [GO:0004518]; transposase activity [GO:0004803]; transposition, DNA-mediated [GO:0006313]	cytosol [GO:0005829]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; nucleoplasm [GO:0005654]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cap snatching [GO:0075526]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of virus [GO:0075733]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; suppression by virus of host RNA polymerase II activity [GO:0039523]; transcription, DNA-templated [GO:0006351]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome maturation [GO:0019070]; viral genome packaging [GO:0019072]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]; virion attachment to host cell [GO:0019062]	transposition, DNA-mediated [GO:0006313]	cap snatching [GO:0075526]; fusion of virus membrane with host plasma membrane [GO:0019064]; intracellular transport of virus [GO:0075733]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; suppression by virus of host RNA polymerase II activity [GO:0039523]; transcription, DNA-templated [GO:0006351]; uncoating of virus [GO:0019061]; viral budding from plasma membrane [GO:0046761]; viral genome maturation [GO:0019070]; viral genome packaging [GO:0019072]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]; virion attachment to host cell [GO:0019062]	cytoplasmic chromosome [GO:0000229]	cytosol [GO:0005829]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; nucleoplasm [GO:0005654]	DNA binding [GO:0003677]; nuclease activity [GO:0004518]; transposase activity [GO:0004803]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d1t0la__d4yb4d___1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; 2-oxoglutarate metabolic process [GO:0006103]; female gonad development [GO:0008585]; glutathione metabolic process [GO:0006749]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; NADPH regeneration [GO:0006740]; neutrophil degranulation [GO:0043312]; protein targeting to peroxisome [GO:0006625]; regulation of phospholipid biosynthetic process [GO:0071071]; regulation of phospholipid catabolic process [GO:0060696]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; tricarboxylic acid cycle [GO:0006099]	homoisocitrate dehydrogenase activity [GO:0047046]; metal ion binding [GO:0046872]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	2-oxoglutarate metabolic process [GO:0006103]; female gonad development [GO:0008585]; glutathione metabolic process [GO:0006749]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADPH regeneration [GO:0006740]; NADP metabolic process [GO:0006739]; neutrophil degranulation [GO:0043312]; protein targeting to peroxisome [GO:0006625]; regulation of phospholipid biosynthetic process [GO:0071071]; regulation of phospholipid catabolic process [GO:0060696]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; tricarboxylic acid cycle [GO:0006099]	lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]		cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]	homoisocitrate dehydrogenase activity [GO:0047046]; metal ion binding [GO:0046872]
d1t0lc__d1hj6a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; 2-oxoglutarate metabolic process [GO:0006103]; female gonad development [GO:0008585]; glutathione metabolic process [GO:0006749]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; NADPH regeneration [GO:0006740]; neutrophil degranulation [GO:0043312]; protein targeting to peroxisome [GO:0006625]; regulation of phospholipid biosynthetic process [GO:0071071]; regulation of phospholipid catabolic process [GO:0060696]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	2-oxoglutarate metabolic process [GO:0006103]; female gonad development [GO:0008585]; glutathione metabolic process [GO:0006749]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADPH regeneration [GO:0006740]; NADP metabolic process [GO:0006739]; neutrophil degranulation [GO:0043312]; protein targeting to peroxisome [GO:0006625]; regulation of phospholipid biosynthetic process [GO:0071071]; regulation of phospholipid catabolic process [GO:0060696]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1t0ma1_d2eysa2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1t0ma2_d1t7ya2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]
d1t0md2_d3lkpa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1t0me__d1q1jm2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1t0nb__d3u7wl2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1t0nd1_d4jrec2__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; inorganic anion exchanger activity [GO:0005452]; nitrate transmembrane transporter activity [GO:0015112]; nitrite efflux transmembrane transporter activity [GO:0015514]; nitrate assimilation [GO:0042128]; nitrate transport [GO:0015706]; nitrite transport [GO:0015707]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	nitrate assimilation [GO:0042128]; nitrate transport [GO:0015706]; nitrite transport [GO:0015707]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	inorganic anion exchanger activity [GO:0005452]; nitrate transmembrane transporter activity [GO:0015112]; nitrite efflux transmembrane transporter activity [GO:0015514]
d1t0ne__d1wcbl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1t0pa__d1m1xb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]
d1t0qb__d3e1qc___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1t0qc__d4p1bc___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]	toluene catabolic process [GO:0042203]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1t0rc__d3q3mg___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]	toluene catabolic process [GO:0042203]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1t0sc__d3q3mc___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]	toluene catabolic process [GO:0042203]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1t0tw__d1vdhe___1			Firmicutes	Deinococcus-Thermus	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1t0ty__d1vdhd___1			Firmicutes	Deinococcus-Thermus	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1t0ty__d5b0fb___1		Viridiplantae	Firmicutes	Streptophyta	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytoplasm [GO:0005737]; cyclase activity [GO:0009975]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; cannabinoid biosynthetic process [GO:1901696]; olivetolic acid biosynthetic process [GO:1901697]		cannabinoid biosynthetic process [GO:1901696]; olivetolic acid biosynthetic process [GO:1901697]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cyclase activity [GO:0009975]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]
d1t0ub__d3qpbg___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	uridine phosphorylase activity [GO:0004850]
d1t0ub__d3t94d___1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]
d1t11b2_d1p9yb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; 'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein transport [GO:0015031]; protein unfolding [GO:0043335]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; 'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]; response to heat [GO:0009408]	'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein transport [GO:0015031]; protein unfolding [GO:0043335]	'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]; response to heat [GO:0009408]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]	identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]
d1t12a__d2n2za___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lipid binding [GO:0008289]; defense response [GO:0006952]; lipid transport [GO:0006869]; response to biotic stimulus [GO:0009607]	lipid binding [GO:0008289]; defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]; lipid transport [GO:0006869]	defense response [GO:0006952]; lipid transport [GO:0006869]; response to biotic stimulus [GO:0009607]	defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]; lipid transport [GO:0006869]			lipid binding [GO:0008289]	lipid binding [GO:0008289]
d1t13c__d4kq6j___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	mitochondrial intermembrane space [GO:0005758]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]	mitochondrial intermembrane space [GO:0005758]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1t14a__d2wcha___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	odorant binding [GO:0005549]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]		dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]	odorant binding [GO:0005549]
d1t15a2_d1l7ba___1	Metazoa		Chordata	Deinococcus-Thermus	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; gamma-tubulin ring complex [GO:0008274]; lateral element [GO:0000800]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151]; androgen receptor binding [GO:0050681]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; androgen receptor signaling pathway [GO:0030521]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to indole-3-methanol [GO:0071681]; cellular response to tumor necrosis factor [GO:0071356]; centrosome cycle [GO:0007098]; chordate embryonic development [GO:0043009]; chromosome segregation [GO:0007059]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; fatty acid biosynthetic process [GO:0006633]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of centriole replication [GO:0046600]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of DNA repair [GO:0045739]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of histone H4-K20 methylation [GO:0070512]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; response to estrogen [GO:0043627]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	androgen receptor signaling pathway [GO:0030521]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to indole-3-methanol [GO:0071681]; cellular response to tumor necrosis factor [GO:0071356]; centrosome cycle [GO:0007098]; chordate embryonic development [GO:0043009]; chromosome segregation [GO:0007059]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; fatty acid biosynthetic process [GO:0006633]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of centriole replication [GO:0046600]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of DNA repair [GO:0045739]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of histone H4-K20 methylation [GO:0070512]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; response to estrogen [GO:0043627]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; gamma-tubulin ring complex [GO:0008274]; lateral element [GO:0000800]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151]		androgen receptor binding [GO:0050681]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]
d1t19a__d4eetb___1		Viridiplantae	Proteobacteria	Streptophyta	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cell [GO:0005623]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plastid [GO:0009536]; ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein serine/threonine kinase activity [GO:0004674]; chloroplast relocation [GO:0009902]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-chromophore linkage [GO:0018298]; response to blue light [GO:0009637]; stomatal movement [GO:0010118]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	chloroplast relocation [GO:0009902]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; protein phosphorylation [GO:0006468]; response to blue light [GO:0009637]; stomatal movement [GO:0010118]		cell [GO:0005623]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plastid [GO:0009536]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein serine/threonine kinase activity [GO:0004674]
d1t1ca__d1ot9a___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d1t1da__d1qdwa___1	Metazoa	Metazoa	Mollusca	Chordata	voltage-gated potassium channel complex [GO:0008076]; voltage-gated potassium channel activity [GO:0005249]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	voltage-gated potassium channel complex [GO:0008076]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	voltage-gated potassium channel activity [GO:0005249]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]
d1t1da__d3ohvc___1	Metazoa	Metazoa	Mollusca	Chordata	voltage-gated potassium channel complex [GO:0008076]; voltage-gated potassium channel activity [GO:0005249]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; import into nucleus [GO:0051170]; primary adaptive immune response involving T cells and B cells [GO:0090721]; regulation of transcription, DNA-templated [GO:0006355]	protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]	import into nucleus [GO:0051170]; primary adaptive immune response involving T cells and B cells [GO:0090721]; regulation of transcription, DNA-templated [GO:0006355]	voltage-gated potassium channel complex [GO:0008076]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	voltage-gated potassium channel activity [GO:0005249]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]
d1t1ga__d1y9za___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1t1ia__d3d43b___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1t1ja1_d1r16b___1		Metazoa	Proteobacteria	Mollusca		cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]		single fertilization [GO:0007338]		cytoplasmic vesicle [GO:0031410]		NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]
d1t1sa1_d1r0la1__1			Proteobacteria	Proteobacteria	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; metal ion binding [GO:0046872]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; metal ion binding [GO:0046872]; NADPH binding [GO:0070402]
d1t1sa4_d1ps8a2__1			Proteobacteria	Proteobacteria	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]			1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]
d1t1ua1_d4n72a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]; choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]; acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]	pyruvate dehydrogenase complex [GO:0045254]	choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]
d1t1ua2_d1q23f___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]; choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]; acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]		choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d1t1wa1_d5fcsh1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1t1xb__d3bdbf___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1t1xb__d3qdma2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1t1ya1_d3ojvc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1t1yb__d3cfkb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1t1za1_d5hyec2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1t1za2_d2zokc2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1t20b__d3sqol1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor recycling [GO:0001920]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of receptor recycling [GO:0001920]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]
d1t21a1_d6b3sd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d1t21b__d3owee___1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	pathogenesis [GO:0009405]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1t22a1_d1f6ad2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1t22a1_d2iq9l1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	metal ion binding [GO:0046872]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]
d1t22a2_d2bckd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1t22b__d1ub5b1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1t24a2_d3h3fh2__1		Metazoa	Apicomplexa	Chordata	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d1t25a1_d1a9za___1			Apicomplexa	Proteobacteria	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]; carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	L-lactate dehydrogenase activity [GO:0004459]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]
d1t29a1_d3cojg1__1	Metazoa	Metazoa	Chordata	Chordata	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; gamma-tubulin ring complex [GO:0008274]; lateral element [GO:0000800]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151]; androgen receptor binding [GO:0050681]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; androgen receptor signaling pathway [GO:0030521]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to indole-3-methanol [GO:0071681]; cellular response to tumor necrosis factor [GO:0071356]; centrosome cycle [GO:0007098]; chordate embryonic development [GO:0043009]; chromosome segregation [GO:0007059]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; fatty acid biosynthetic process [GO:0006633]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of centriole replication [GO:0046600]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of DNA repair [GO:0045739]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of histone H4-K20 methylation [GO:0070512]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; response to estrogen [GO:0043627]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; acetyl-CoA metabolic process [GO:0006084]; carnitine shuttle [GO:0006853]; cellular response to prostaglandin E stimulus [GO:0071380]; fatty acid biosynthetic process [GO:0006633]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lipid homeostasis [GO:0055088]; malonyl-CoA biosynthetic process [GO:2001295]; positive regulation of cellular metabolic process [GO:0031325]; protein homotetramerization [GO:0051289]; protein metabolic process [GO:0019538]; regulation of cholesterol biosynthetic process [GO:0045540]; tissue homeostasis [GO:0001894]	androgen receptor signaling pathway [GO:0030521]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to indole-3-methanol [GO:0071681]; cellular response to tumor necrosis factor [GO:0071356]; centrosome cycle [GO:0007098]; chordate embryonic development [GO:0043009]; chromosome segregation [GO:0007059]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; fatty acid biosynthetic process [GO:0006633]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of centriole replication [GO:0046600]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of DNA repair [GO:0045739]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of histone H4-K20 methylation [GO:0070512]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; response to estrogen [GO:0043627]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	acetyl-CoA metabolic process [GO:0006084]; carnitine shuttle [GO:0006853]; cellular response to prostaglandin E stimulus [GO:0071380]; fatty acid biosynthetic process [GO:0006633]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lipid homeostasis [GO:0055088]; malonyl-CoA biosynthetic process [GO:2001295]; positive regulation of cellular metabolic process [GO:0031325]; protein homotetramerization [GO:0051289]; protein metabolic process [GO:0019538]; regulation of cholesterol biosynthetic process [GO:0045540]; tissue homeostasis [GO:0001894]	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; gamma-tubulin ring complex [GO:0008274]; lateral element [GO:0000800]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151]	actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; fibrillar center [GO:0001650]	androgen receptor binding [GO:0050681]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1t2ea2_d2x0ra2__1			Apicomplexa	Euryarchaeota	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]
d1t2ea2_d3h3jb2__1			Apicomplexa	Firmicutes	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d1t2ha__d1brka___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1t2ja1_d1rzkc2__1	Metazoa	Metazoa	Chordata	Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1t2na__d4fkba___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d1t2na__d5t4ea2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1t2ql2_d2ombc2__1	Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d1t2ua1_d1gzhd2__1	Metazoa	Metazoa	Chordata	Chordata	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; gamma-tubulin ring complex [GO:0008274]; lateral element [GO:0000800]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151]; androgen receptor binding [GO:0050681]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; androgen receptor signaling pathway [GO:0030521]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to indole-3-methanol [GO:0071681]; cellular response to tumor necrosis factor [GO:0071356]; centrosome cycle [GO:0007098]; chordate embryonic development [GO:0043009]; chromosome segregation [GO:0007059]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; fatty acid biosynthetic process [GO:0006633]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of centriole replication [GO:0046600]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of DNA repair [GO:0045739]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of histone H4-K20 methylation [GO:0070512]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; response to estrogen [GO:0043627]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	androgen receptor signaling pathway [GO:0030521]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to indole-3-methanol [GO:0071681]; cellular response to tumor necrosis factor [GO:0071356]; centrosome cycle [GO:0007098]; chordate embryonic development [GO:0043009]; chromosome segregation [GO:0007059]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; fatty acid biosynthetic process [GO:0006633]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of centriole replication [GO:0046600]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of DNA repair [GO:0045739]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of histone H4-K20 methylation [GO:0070512]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; response to estrogen [GO:0043627]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; gamma-tubulin ring complex [GO:0008274]; lateral element [GO:0000800]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	androgen receptor binding [GO:0050681]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1t2xa1_d4yefd___1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; fatty acid biosynthetic process [GO:0006633]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; regulation of catalytic activity [GO:0050790]		fatty acid biosynthetic process [GO:0006633]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; regulation of catalytic activity [GO:0050790]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]
d1t2xa2_d1ghoo3__1	Fungi		Ascomycota		extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]				extracellular region [GO:0005576]		galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	
d1t2xa3_d2eiba3__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]
d1t31a__d1ppfe___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptide binding [GO:0042277]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; angiotensin maturation [GO:0002003]; basement membrane disassembly [GO:0034769]; cellular response to glucose stimulus [GO:0071333]; extracellular matrix disassembly [GO:0022617]; interleukin-1 beta biosynthetic process [GO:0050720]; midbrain development [GO:0030901]; positive regulation of angiogenesis [GO:0045766]; regulation of inflammatory response [GO:0050727]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	angiotensin maturation [GO:0002003]; basement membrane disassembly [GO:0034769]; cellular response to glucose stimulus [GO:0071333]; extracellular matrix disassembly [GO:0022617]; interleukin-1 beta biosynthetic process [GO:0050720]; midbrain development [GO:0030901]; positive regulation of angiogenesis [GO:0045766]; regulation of inflammatory response [GO:0050727]		cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	extracellular region [GO:0005576]	peptide binding [GO:0042277]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1t32a__d4x2vd___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; angiotensin maturation [GO:0002003]; antibacterial humoral response [GO:0019731]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of gram-positive bacterium [GO:0070946]; positive regulation of immune response [GO:0050778]; protein phosphorylation [GO:0006468]; proteolysis [GO:0006508]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	angiotensin maturation [GO:0002003]; antibacterial humoral response [GO:0019731]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cellular response to lipopolysaccharide [GO:0071222]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of gram-positive bacterium [GO:0070946]; positive regulation of immune response [GO:0050778]; protein phosphorylation [GO:0006468]; proteolysis [GO:0006508]	transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	azurophil granule lumen [GO:0035578]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]		heparin binding [GO:0008201]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]
d1t33a1_d5mysa1__1			Proteobacteria	Actinobacteria	DNA binding [GO:0003677]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1t33b1_d1rpwb1__1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]		negative regulation of transcription, DNA-templated [GO:0045892]			DNA binding [GO:0003677]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1t33b1_d5gp9a1__1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]	DNA binding [GO:0003677]					DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1t36a2_d1zcza1__1			Proteobacteria	Thermotogae	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]
d1t36a3_d2v58b1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1t36a3_d5lxsf1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1t36a4_d2i87a1__1			Proteobacteria	Firmicutes	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1t36c2_d1ik4b___1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	methylglyoxal synthase activity [GO:0008929]
d1t36c3_d1ehib1__1			Proteobacteria	Firmicutes	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1t36c4_d5c1pd1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d1t36e2_d1wo8d___1			Proteobacteria	Deinococcus-Thermus	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	methylglyoxal synthase activity [GO:0008929]
d1t36e3_d5cb4f1__1		Metazoa	Proteobacteria	Chordata	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]; tubulin binding [GO:0015631]; microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	tubulin binding [GO:0015631]
d1t36e4_d1bncb2__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1t36g2_d1wo8f___1			Proteobacteria	Deinococcus-Thermus	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	methylglyoxal synthase activity [GO:0008929]
d1t36g3_d1m6vc3__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1t36g4_d2w71c1__1			Proteobacteria	Proteobacteria	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1t38a1_d3kzyb2__1	Metazoa		Chordata		membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; metal ion binding [GO:0046872]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; methyltransferase activity [GO:0008168]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of double-strand break repair [GO:2000781]		DNA dealkylation involved in DNA repair [GO:0006307]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of double-strand break repair [GO:2000781]		membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; metal ion binding [GO:0046872]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; methyltransferase activity [GO:0008168]	
d1t39b1_d3kzya2__1	Metazoa		Chordata		membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; metal ion binding [GO:0046872]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; methyltransferase activity [GO:0008168]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of double-strand break repair [GO:2000781]		DNA dealkylation involved in DNA repair [GO:0006307]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of double-strand break repair [GO:2000781]		membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; metal ion binding [GO:0046872]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; methyltransferase activity [GO:0008168]	
d1t3ab__d1utza___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	negative regulation of neurotransmitter secretion [GO:0046929]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1t3ca__d2ovza___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	negative regulation of neurotransmitter secretion [GO:0046929]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1t3fa1_d3cfko2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1t3fa2_d5mwnn___1				Proteobacteria								
d1t3fb1_d1q9qa3__1												
d1t3fb2_d1ow0d1__1		Metazoa		Chordata		extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]
d1t3ka__d2ifda___1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; arsenate reductase (glutaredoxin) activity [GO:0008794]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]; cell cycle [GO:0007049]; cell division [GO:0051301]; protein phosphorylation [GO:0006468]; response to arsenic-containing substance [GO:0046685]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	cell cycle [GO:0007049]; cell division [GO:0051301]; protein phosphorylation [GO:0006468]; response to arsenic-containing substance [GO:0046685]	cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	chloroplast [GO:0009507]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	arsenate reductase (glutaredoxin) activity [GO:0008794]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]	phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]
d1t3la2_d1oe0d___1	Metazoa	Metazoa	Chordata	Arthropoda	L-type voltage-gated calcium channel complex [GO:1990454]; photoreceptor ribbon synapse [GO:0098684]; presynapse [GO:0098793]; actin filament binding [GO:0051015]; high voltage-gated calcium channel activity [GO:0008331]; voltage-gated calcium channel activity involved in AV node cell action potential [GO:0086056]; voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels [GO:0099635]; calcium ion import [GO:0070509]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; positive regulation of calcium ion transport [GO:0051928]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	calcium ion import [GO:0070509]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; positive regulation of calcium ion transport [GO:0051928]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; visual perception [GO:0007601]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	L-type voltage-gated calcium channel complex [GO:1990454]; photoreceptor ribbon synapse [GO:0098684]; presynapse [GO:0098793]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	actin filament binding [GO:0051015]; high voltage-gated calcium channel activity [GO:0008331]; voltage-gated calcium channel activity involved in AV node cell action potential [GO:0086056]; voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels [GO:0099635]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]
d1t3na1_d2w9aa2__1	Metazoa		Chordata	Crenarchaeota	cytoplasmic ribonucleoprotein granule [GO:0036464]; intracellular [GO:0005622]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasmic ribonucleoprotein granule [GO:0036464]; intracellular [GO:0005622]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d1t3nb1_d2va2a1__1	Metazoa		Chordata	Crenarchaeota	cytoplasmic ribonucleoprotein granule [GO:0036464]; intracellular [GO:0005622]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasmic ribonucleoprotein granule [GO:0036464]; intracellular [GO:0005622]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d1t3qc2_d1hska1__1			Proteobacteria	Firmicutes	oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; UDP-N-acetylmuramate dehydrogenase activity [GO:0008762]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]		cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]		cytoplasm [GO:0005737]	oxidoreductase activity [GO:0016491]	FAD binding [GO:0071949]; UDP-N-acetylmuramate dehydrogenase activity [GO:0008762]
d1t3qd1_d4c7ya2__1			Proteobacteria	Proteobacteria	oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1t3qd2_d1fxid___1			Proteobacteria	Cyanobacteria	oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1t3qd2_d1n63a2__1			Proteobacteria	Proteobacteria	oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1t3qf2_d2qpma1__1		Viridiplantae	Proteobacteria	Streptophyta	oxidoreductase activity [GO:0016491]	extracellular space [GO:0005615]; cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]		cytokinin metabolic process [GO:0009690]		extracellular space [GO:0005615]	oxidoreductase activity [GO:0016491]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]
d1t3ta3_d1twjc___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]
d1t3ta4_d3c9rb1__1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]
d1t3ta4_d5cm7b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]
d1t3ta5_d3u0ob1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]; selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]
d1t41a__d4l1wb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytosol [GO:0005829]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]
d1t47b2_d1t47a1__1			Actinobacteria	Actinobacteria	4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]			4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]	4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]
d1t4ba2_d1c3vb2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; cellular response to DNA damage stimulus [GO:0006974]; diaminopimelate biosynthetic process [GO:0019877]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	'de novo' L-methionine biosynthetic process [GO:0071266]; cellular response to DNA damage stimulus [GO:0006974]; diaminopimelate biosynthetic process [GO:0019877]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]
d1t4ba2_d1dssg2__1		Metazoa	Proteobacteria	Arthropoda	cytosol [GO:0005829]; aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; cellular response to DNA damage stimulus [GO:0006974]; diaminopimelate biosynthetic process [GO:0019877]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	'de novo' L-methionine biosynthetic process [GO:0071266]; cellular response to DNA damage stimulus [GO:0006974]; diaminopimelate biosynthetic process [GO:0019877]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1t4bb2_d1yl7c2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; cellular response to DNA damage stimulus [GO:0006974]; diaminopimelate biosynthetic process [GO:0019877]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	'de novo' L-methionine biosynthetic process [GO:0071266]; cellular response to DNA damage stimulus [GO:0006974]; diaminopimelate biosynthetic process [GO:0019877]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]
d1t4db2_d1u8fq2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; cellular response to DNA damage stimulus [GO:0006974]; diaminopimelate biosynthetic process [GO:0019877]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]	'de novo' L-methionine biosynthetic process [GO:0071266]; cellular response to DNA damage stimulus [GO:0006974]; diaminopimelate biosynthetic process [GO:0019877]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]
d1t4ea2_d3lbje___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; 5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]
d1t4fm__d2n14a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; 5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]
d1t4ka1_d1uweh2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1t4kb1_d1epfd2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]
d1t4kc2_d2bocb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1t4kd1_d5wjoc1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1t4kd2_d2v2wa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1t4kd2_d5e5ub2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; toxin transport [GO:1901998]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; toxin transport [GO:1901998]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]
d1t4pb__d5rlac___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1t4pc__d5g0ha___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]
d1t4qa__d2afga___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1t4ra__d5efhd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]
d1t4rb__d1p8na___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1t4rc__d4gwda___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1t4sb__d1woif1__1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	agmatinase activity [GO:0008783]; metal ion binding [GO:0046872]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	agmatinase activity [GO:0008783]; metal ion binding [GO:0046872]
d1t4tc__d3kv2b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1t4za1_d5hr1f___1			Cyanobacteria	Proteobacteria	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; circadian rhythm [GO:0007623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	circadian rhythm [GO:0007623]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1t5fc__d4rlaa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1t5ga__d3sjta___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1t5ka__d2i7oa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1t5ka__d4ysec1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1t5kb__d2azab___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1t5kd__d4n24a1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; chromatin-mediated maintenance of transcription [GO:0048096]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]		cellular response to leukemia inhibitory factor [GO:1990830]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin organization [GO:0006325]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]	periplasmic space [GO:0042597]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]
d1t5ob1_d4eudb2__1			Euryarchaeota	Proteobacteria	S-methyl-5-thioribose-1-phosphate isomerase activity [GO:0046523]; L-methionine salvage from S-adenosylmethionine [GO:0019284]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	L-methionine salvage from S-adenosylmethionine [GO:0019284]	acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]			S-methyl-5-thioribose-1-phosphate isomerase activity [GO:0046523]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d1t5wa2_d4ozgc1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1t5we2_d4d0ca2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	protein homodimerization activity [GO:0042803]
d1t5xb1_d4eurb1__1	Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	
d1t5xd2_d2rdhc2__1	Metazoa		Chordata	Firmicutes	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	pathogenesis [GO:0009405]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	extracellular region [GO:0005576]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	
d1t60d1_d1t60a2__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]			basement membrane [GO:0005604]; collagen trimer [GO:0005581]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]
d1t60g1_d1t60u2__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]			basement membrane [GO:0005604]; collagen trimer [GO:0005581]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]
d1t60l1_d1t61b2__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]			basement membrane [GO:0005604]; collagen trimer [GO:0005581]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]
d1t60o1_d1m3dh2__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]			basement membrane [GO:0005604]; collagen trimer [GO:0005581]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]
d1t60r1_d1li1a1__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	collagen type IV trimer [GO:0005587]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; aging [GO:0007568]; angiogenesis [GO:0001525]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; negative regulation of angiogenesis [GO:0016525]; response to activity [GO:0014823]; transcription, DNA-templated [GO:0006351]		aging [GO:0007568]; angiogenesis [GO:0001525]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; negative regulation of angiogenesis [GO:0016525]; response to activity [GO:0014823]; transcription, DNA-templated [GO:0006351]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	collagen-containing extracellular matrix [GO:0062023]; collagen type IV trimer [GO:0005587]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]
d1t60v1_d1m3da2__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]			basement membrane [GO:0005604]; collagen trimer [GO:0005581]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]
d1t61a1_d1li1a2__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	collagen type IV trimer [GO:0005587]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]; aging [GO:0007568]; angiogenesis [GO:0001525]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; negative regulation of angiogenesis [GO:0016525]; response to activity [GO:0014823]; transcription, DNA-templated [GO:0006351]		aging [GO:0007568]; angiogenesis [GO:0001525]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; negative regulation of angiogenesis [GO:0016525]; response to activity [GO:0014823]; transcription, DNA-templated [GO:0006351]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	collagen-containing extracellular matrix [GO:0062023]; collagen type IV trimer [GO:0005587]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]; extracellular matrix structural constituent conferring tensile strength [GO:0030020]
d1t61c1_d1t60k1__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]			basement membrane [GO:0005604]; collagen trimer [GO:0005581]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]
d1t61f1_d1t61e1__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; extracellular matrix structural constituent [GO:0005201]			basement membrane [GO:0005604]; collagen trimer [GO:0005581]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]	extracellular matrix structural constituent [GO:0005201]	extracellular matrix structural constituent [GO:0005201]
d1t64a__d3e6va___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1t64b__d2v5wb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]	histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]
d1t64b__d4rlac___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1t65a__d5k3lb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; thyroid hormone receptor coactivator activity [GO:0030375]; transcription coactivator activity [GO:0003713]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; circadian regulation of gene expression [GO:0032922]; locomotor rhythm [GO:0045475]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription, DNA-templated [GO:0006355]; response to progesterone [GO:0032570]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; circadian regulation of gene expression [GO:0032922]; locomotor rhythm [GO:0045475]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription, DNA-templated [GO:0006355]; response to progesterone [GO:0032570]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; thyroid hormone receptor coactivator activity [GO:0030375]; transcription coactivator activity [GO:0003713]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d1t66h1_d1deea1__1	Metazoa		Chordata	Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]		IgG binding [GO:0019864]
d1t66l1_d1g7pa1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1t66l2_d1s7ud1__1	Metazoa	Metazoa	Chordata	Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1t66l2_d2gfbf1__1	Metazoa		Chordata									
d1t68x2_d4oddb___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	small molecule binding [GO:0036094]	vasodilation [GO:0042311]		extracellular region [GO:0005576]		histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	small molecule binding [GO:0036094]
d1t6gc__d5ewsn___1	Viridiplantae	Metazoa	Streptophyta	Chordata	aspartic-type endopeptidase activity [GO:0004190]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	xylan catabolic process [GO:0045493]				aspartic-type endopeptidase activity [GO:0004190]; hydrolase activity, acting on glycosyl bonds [GO:0016798]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d1t6gd__d1ms1a1__1	Viridiplantae		Streptophyta		aspartic-type endopeptidase activity [GO:0004190]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; xylan catabolic process [GO:0045493]	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	xylan catabolic process [GO:0045493]	pathogenesis [GO:0009405]			aspartic-type endopeptidase activity [GO:0004190]; hydrolase activity, acting on glycosyl bonds [GO:0016798]	exo-alpha-sialidase activity [GO:0004308]
d1t6la1_d6amsd3__1				Proteobacteria	host cell nucleus [GO:0042025]; virion [GO:0019012]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA strand elongation involved in DNA replication [GO:0006271]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA strand elongation involved in DNA replication [GO:0006271]	host cell nucleus [GO:0042025]; virion [GO:0019012]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1t6mb__d2plca___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]; pathogenesis [GO:0009405]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]
d1t6qa__d3g4xc___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d1t6qb__d1q0dg___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d1t6uc__d1q0gj___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d1t6ud__d1q0ff___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d1t6ue__d1q0kk___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d1t6ug__d4ncqc___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d1t6uk__d1q0gh___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d1t6vo__d5ezlb2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1t6xa2_d1k4ka___1			Thermotogae	Proteobacteria	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]; FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; 'de novo' NAD biosynthetic process from aspartate [GO:0034628]; NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	'de novo' NAD biosynthetic process from aspartate [GO:0034628]; NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]			ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]
d1t6ya2_d1b6ta___1			Thermotogae	Proteobacteria	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]; FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1t6yb2_d4nx2a1__1			Thermotogae	Euryarchaeota	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]; FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	tyrosyl-tRNA aminoacylation [GO:0006437]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]
d1t6zb2_d2qujb___1		Metazoa	Thermotogae	Chordata	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]; FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; kinase inhibitor activity [GO:0019210]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tryptophan-tRNA ligase activity [GO:0004830]; angiogenesis [GO:0001525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; regulation of angiogenesis [GO:0045765]; regulation of protein ADP-ribosylation [GO:0010835]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	angiogenesis [GO:0001525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; regulation of angiogenesis [GO:0045765]; regulation of protein ADP-ribosylation [GO:0010835]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]	ATP binding [GO:0005524]; kinase inhibitor activity [GO:0019210]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tryptophan-tRNA ligase activity [GO:0004830]
d1t6zb2_d5ts2c1__1			Thermotogae	Proteobacteria	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]; FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; [citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]	[citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1t70g__d2qfrb2__1		Viridiplantae	Deinococcus-Thermus	Streptophyta	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]; phosphoenolpyruvate phosphatase activity [GO:0050189]	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]				extracellular region [GO:0005576]	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]; phosphoenolpyruvate phosphatase activity [GO:0050189]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]
d1t70h__d5j28b___1		Metazoa	Deinococcus-Thermus	Chordata	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]; phosphoenolpyruvate phosphatase activity [GO:0050189]	cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; protein-containing complex [GO:0032991]; PTW/PP1 phosphatase complex [GO:0072357]; lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]		cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]		cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]; phosphoenolpyruvate phosphatase activity [GO:0050189]	lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]
d1t75e__d3e24a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbon utilization [GO:0015976]	carbon utilization [GO:0015976]	cytosol [GO:0005829]		carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1t75e__d5swcb1__1			Proteobacteria	Cyanobacteria	cytosol [GO:0005829]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	cytoplasm [GO:0005737]; carbonate dehydratase activity [GO:0004089]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]; cyanate catabolic process [GO:0009440]	carbon utilization [GO:0015976]	carbon utilization [GO:0015976]; cyanate catabolic process [GO:0009440]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d1t77a2_d4p7ib3__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; membrane [GO:0016020]; plasma membrane [GO:0005886]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]		actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; membrane [GO:0016020]; plasma membrane [GO:0005886]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]		actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d1t7jb__d1g35a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1t7ka__d2aoha___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1t7ka__d2g1rb___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d1t7oa1_d1t7oa2__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	carnitine O-acetyltransferase activity [GO:0004092]	carnitine O-acetyltransferase activity [GO:0004092]
d1t7pb__d2c3tb1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]
d1t7qa1_d3maec___1	Metazoa		Chordata		endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]		carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]		endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]		carnitine O-acetyltransferase activity [GO:0004092]	
d1t7qb2_d1q23k___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	response to antibiotic [GO:0046677]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]		carnitine O-acetyltransferase activity [GO:0004092]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d1t7qb2_d1s5oa1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; protein targeting to peroxisome [GO:0006625]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; protein targeting to peroxisome [GO:0006625]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	carnitine O-acetyltransferase activity [GO:0004092]	carnitine O-acetyltransferase activity [GO:0004092]
d1t7va1_d3o2vl2__1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]		collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	
d1t7wa1_d1fski2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1t7wa1_d5v7jl1__1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1t7wa2_d4e41b1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1t7xa2_d1ao7a2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1t7ya1_d3sobl2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	caveola [GO:0005901]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]; Wnt-Frizzled-LRP5/6 complex [GO:1990851]; apolipoprotein binding [GO:0034185]; coreceptor activity involved in canonical Wnt signaling pathway [GO:1904928]; coreceptor activity involved in Wnt signaling pathway [GO:0071936]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; kinase inhibitor activity [GO:0019210]; low-density lipoprotein particle receptor activity [GO:0005041]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; toxin transmembrane transporter activity [GO:0019534]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; anterior/posterior pattern specification [GO:0009952]; axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; gastrulation with mouth forming second [GO:0001702]; midbrain development [GO:0030901]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; roof of mouth development [GO:0060021]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	anterior/posterior pattern specification [GO:0009952]; axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; gastrulation with mouth forming second [GO:0001702]; midbrain development [GO:0030901]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; roof of mouth development [GO:0060021]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	caveola [GO:0005901]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202]; Wnt-Frizzled-LRP5/6 complex [GO:1990851]; Wnt signalosome [GO:1990909]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	apolipoprotein binding [GO:0034185]; coreceptor activity involved in canonical Wnt signaling pathway [GO:1904928]; coreceptor activity involved in Wnt signaling pathway [GO:0071936]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; kinase inhibitor activity [GO:0019210]; low-density lipoprotein particle receptor activity [GO:0005041]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; toxin transmembrane transporter activity [GO:0019534]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]
d1t7ya2_d4p57c1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d1t7za1_d2v9qa2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]
d1t7za2_d5ksud1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of membrane [GO:0016021]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; macrophage migration inhibitory factor receptor complex [GO:0035692]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; NOS2-CD74 complex [GO:0035693]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; vacuole [GO:0005773]; amyloid-beta binding [GO:0001540]; CD4 receptor binding [GO:0042609]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; macrophage migration inhibitory factor binding [GO:0035718]; MHC class II protein binding [GO:0042289]; MHC class II protein binding, via antigen binding groove [GO:0042658]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase binding [GO:0050998]; protein folding chaperone [GO:0044183]; activation of MAPK activity [GO:0000187]; antigen processing and presentation of endogenous antigen [GO:0019883]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell population proliferation [GO:0008283]; chaperone cofactor-dependent protein refolding [GO:0051085]; defense response [GO:0006952]; immunoglobulin mediated immune response [GO:0016064]; intracellular protein transport [GO:0006886]; leukocyte migration [GO:0050900]; macrophage migration inhibitory factor signaling pathway [GO:0035691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of peptide secretion [GO:0002792]; negative regulation of T cell differentiation [GO:0045581]; negative thymic T cell selection [GO:0045060]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of kinase activity [GO:0033674]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of macrophage migration inhibitory factor signaling pathway [GO:2000448]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of viral entry into host cell [GO:0046598]; positive thymic T cell selection [GO:0045059]; prostaglandin biosynthetic process [GO:0001516]; protein heterotetramerization [GO:0051290]; protein trimerization [GO:0070206]; protein-containing complex assembly [GO:0065003]; regulation of macrophage activation [GO:0043030]; signal transduction [GO:0007165]; T cell selection [GO:0045058]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	activation of MAPK activity [GO:0000187]; antigen processing and presentation of endogenous antigen [GO:0019883]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell population proliferation [GO:0008283]; chaperone cofactor-dependent protein refolding [GO:0051085]; defense response [GO:0006952]; immunoglobulin mediated immune response [GO:0016064]; intracellular protein transport [GO:0006886]; leukocyte migration [GO:0050900]; macrophage migration inhibitory factor signaling pathway [GO:0035691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of peptide secretion [GO:0002792]; negative regulation of T cell differentiation [GO:0045581]; negative thymic T cell selection [GO:0045060]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of kinase activity [GO:0033674]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of macrophage migration inhibitory factor signaling pathway [GO:2000448]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of viral entry into host cell [GO:0046598]; positive thymic T cell selection [GO:0045059]; prostaglandin biosynthetic process [GO:0001516]; protein-containing complex assembly [GO:0065003]; protein heterotetramerization [GO:0051290]; protein trimerization [GO:0070206]; regulation of macrophage activation [GO:0043030]; signal transduction [GO:0007165]; T cell selection [GO:0045058]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of membrane [GO:0016021]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; macrophage migration inhibitory factor receptor complex [GO:0035692]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; NOS2-CD74 complex [GO:0035693]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; vacuole [GO:0005773]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	amyloid-beta binding [GO:0001540]; CD4 receptor binding [GO:0042609]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; macrophage migration inhibitory factor binding [GO:0035718]; MHC class II protein binding [GO:0042289]; MHC class II protein binding, via antigen binding groove [GO:0042658]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase binding [GO:0050998]; protein folding chaperone [GO:0044183]
d1t80a1_d4hc1n1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; integrin binding involved in cell-matrix adhesion [GO:0098640]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	integrin binding involved in cell-matrix adhesion [GO:0098640]
d1t80a2_d4pjgc1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1t83a2_d2fjfq1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1t83b1_d4elkb1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1t83b2_d5u72e2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1t85a__d2fdvb1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d1t86a__d1og2a___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; (S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	(S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d1t86a__d3awqa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1t89c1_d5d6cl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1t8aa__d4etda___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1t8da__d1kmb21__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d1t8ea1_d1wn7a1__1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; endonuclease activity [GO:0004519]; nucleotide binding [GO:0000166]; DNA-dependent DNA replication [GO:0006261]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	DNA-dependent DNA replication [GO:0006261]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; endonuclease activity [GO:0004519]; nucleotide binding [GO:0000166]
d1t8eb__d1fhea2__1		Metazoa	Proteobacteria	Platyhelminthes	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	glutathione transferase activity [GO:0004364]
d1t8fa__d1c62a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1t8ka__d2fvaa___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	chloroplast [GO:0009507]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	chloroplast [GO:0009507]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	phosphopantetheine binding [GO:0031177]
d1t8pa__d1v37a___1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	catalytic activity [GO:0003824]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]	catalytic activity [GO:0003824]
d1t90a__d1uxua___1			Firmicutes	Crenarchaeota	malonate-semialdehyde dehydrogenase (acetylating) activity [GO:0018478]; methylmalonate-semialdehyde dehydrogenase (acylating) activity [GO:0004491]; inositol catabolic process [GO:0019310]; thymine catabolic process [GO:0006210]; valine catabolic process [GO:0006574]; valine metabolic process [GO:0006573]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	inositol catabolic process [GO:0019310]; thymine catabolic process [GO:0006210]; valine catabolic process [GO:0006574]; valine metabolic process [GO:0006573]				malonate-semialdehyde dehydrogenase (acetylating) activity [GO:0018478]; methylmalonate-semialdehyde dehydrogenase (acylating) activity [GO:0004491]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1t90b__d1o00h___1		Metazoa	Firmicutes	Chordata	malonate-semialdehyde dehydrogenase (acetylating) activity [GO:0018478]; methylmalonate-semialdehyde dehydrogenase (acylating) activity [GO:0004491]; inositol catabolic process [GO:0019310]; thymine catabolic process [GO:0006210]; valine catabolic process [GO:0006574]; valine metabolic process [GO:0006573]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	inositol catabolic process [GO:0019310]; thymine catabolic process [GO:0006210]; valine catabolic process [GO:0006574]; valine metabolic process [GO:0006573]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	malonate-semialdehyde dehydrogenase (acetylating) activity [GO:0018478]; methylmalonate-semialdehyde dehydrogenase (acylating) activity [GO:0004491]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d1t97b__d3gxka___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1t9aa1_d4k9od2__1	Fungi		Ascomycota	Proteobacteria	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mandelate catabolic process [GO:0019596]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1t9aa2_d5tmaa3__1	Fungi		Ascomycota	Proteobacteria	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1t9ab2_d3exee___1	Fungi	Metazoa	Ascomycota	Chordata	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1t9ab3_d1mczh2__1	Fungi		Ascomycota	Proteobacteria	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mandelate catabolic process [GO:0019596]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1t9ba1_d4jufa2__1	Fungi		Ascomycota	Proteobacteria	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mandelate catabolic process [GO:0019596]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1t9ba3_d5imsa1__1	Fungi	Fungi	Ascomycota	Ascomycota	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1t9bb1_d4j16c___1	Fungi		Ascomycota	Deinococcus-Thermus	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]
d1t9bb1_d4mppa2__1	Fungi		Ascomycota	Proteobacteria	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mandelate catabolic process [GO:0019596]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1t9bb3_d2wvha1__1	Fungi		Ascomycota	Proteobacteria	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1t9ca1_d4i5ib___1	Fungi	Metazoa	Ascomycota	Chordata	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cell [GO:0005623]; chromatin silencing complex [GO:0005677]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear envelope [GO:0005635]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nuclear inner membrane [GO:0005637]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; rDNA heterochromatin [GO:0033553]; bHLH transcription factor binding [GO:0043425]; deacetylase activity [GO:0019213]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; histone binding [GO:0042393]; histone deacetylase activity [GO:0004407]; HLH domain binding [GO:0043398]; identical protein binding [GO:0042802]; keratin filament binding [GO:1990254]; metal ion binding [GO:0046872]; mitogen-activated protein kinase binding [GO:0051019]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone deacetylase activity (H3-K9 specific) [GO:0046969]; NAD-dependent protein deacetylase activity [GO:0034979]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein C-terminus binding [GO:0008022]; protein deacetylase activity [GO:0033558]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transferase activity [GO:0016740]; angiogenesis [GO:0001525]; behavioral response to starvation [GO:0042595]; cell aging [GO:0007569]; cellular glucose homeostasis [GO:0001678]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; circadian regulation of gene expression [GO:0032922]; DNA synthesis involved in DNA repair [GO:0000731]; establishment of chromatin silencing [GO:0006343]; fatty acid homeostasis [GO:0055089]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; leptin-mediated signaling pathway [GO:0033210]; macrophage cytokine production [GO:0010934]; macrophage differentiation [GO:0030225]; maintenance of chromatin silencing [GO:0006344]; methylation-dependent chromatin silencing [GO:0006346]; muscle organ development [GO:0007517]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of cell growth [GO:0030308]; negative regulation of cellular response to testosterone stimulus [GO:2000655]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of helicase activity [GO:0051097]; negative regulation of histone H3-K14 acetylation [GO:0071441]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of neuron death [GO:1901215]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; ovulation from ovarian follicle [GO:0001542]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA repair [GO:0045739]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of macroautophagy [GO:0016239]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell differentiation [GO:0051152]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of apoptotic process [GO:0042981]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of brown fat cell differentiation [GO:0090335]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of endodeoxyribonuclease activity [GO:0032071]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid storage [GO:0010883]; regulation of mitotic cell cycle [GO:0007346]; regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035358]; regulation of protein serine/threonine kinase activity [GO:0071900]; regulation of smooth muscle cell apoptotic process [GO:0034391]; response to hydrogen peroxide [GO:0042542]; response to insulin [GO:0032868]; response to leptin [GO:0044321]; response to oxidative stress [GO:0006979]; single strand break repair [GO:0000012]; spermatogenesis [GO:0007283]; stress-induced premature senescence [GO:0090400]; transforming growth factor beta receptor signaling pathway [GO:0007179]; triglyceride mobilization [GO:0006642]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; white fat cell differentiation [GO:0050872]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	angiogenesis [GO:0001525]; behavioral response to starvation [GO:0042595]; cell aging [GO:0007569]; cellular glucose homeostasis [GO:0001678]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; circadian regulation of gene expression [GO:0032922]; DNA synthesis involved in DNA repair [GO:0000731]; establishment of chromatin silencing [GO:0006343]; fatty acid homeostasis [GO:0055089]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; leptin-mediated signaling pathway [GO:0033210]; macrophage cytokine production [GO:0010934]; macrophage differentiation [GO:0030225]; maintenance of chromatin silencing [GO:0006344]; methylation-dependent chromatin silencing [GO:0006346]; muscle organ development [GO:0007517]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of cell growth [GO:0030308]; negative regulation of cellular response to testosterone stimulus [GO:2000655]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of helicase activity [GO:0051097]; negative regulation of histone H3-K14 acetylation [GO:0071441]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of neuron death [GO:1901215]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; ovulation from ovarian follicle [GO:0001542]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA repair [GO:0045739]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of macroautophagy [GO:0016239]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell differentiation [GO:0051152]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of apoptotic process [GO:0042981]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of brown fat cell differentiation [GO:0090335]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of endodeoxyribonuclease activity [GO:0032071]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid storage [GO:0010883]; regulation of mitotic cell cycle [GO:0007346]; regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035358]; regulation of protein serine/threonine kinase activity [GO:0071900]; regulation of smooth muscle cell apoptotic process [GO:0034391]; response to hydrogen peroxide [GO:0042542]; response to insulin [GO:0032868]; response to leptin [GO:0044321]; response to oxidative stress [GO:0006979]; single strand break repair [GO:0000012]; spermatogenesis [GO:0007283]; stress-induced premature senescence [GO:0090400]; transforming growth factor beta receptor signaling pathway [GO:0007179]; triglyceride mobilization [GO:0006642]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; white fat cell differentiation [GO:0050872]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	cell [GO:0005623]; chromatin silencing complex [GO:0005677]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear envelope [GO:0005635]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nuclear inner membrane [GO:0005637]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; rDNA heterochromatin [GO:0033553]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	bHLH transcription factor binding [GO:0043425]; deacetylase activity [GO:0019213]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; histone binding [GO:0042393]; histone deacetylase activity [GO:0004407]; HLH domain binding [GO:0043398]; identical protein binding [GO:0042802]; keratin filament binding [GO:1990254]; metal ion binding [GO:0046872]; mitogen-activated protein kinase binding [GO:0051019]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone deacetylase activity (H3-K9 specific) [GO:0046969]; NAD-dependent protein deacetylase activity [GO:0034979]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein C-terminus binding [GO:0008022]; protein deacetylase activity [GO:0033558]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transferase activity [GO:0016740]
d1t9cb3_d2vk1b1__1	Fungi	Fungi	Ascomycota	Ascomycota	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1t9da2_d1mczp3__1	Fungi		Ascomycota	Proteobacteria	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mandelate catabolic process [GO:0019596]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1t9da3_d3exed1__1	Fungi	Metazoa	Ascomycota	Chordata	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1t9db1_d2g1ic2__1	Fungi		Ascomycota		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	
d1t9db2_d1mcze2__1	Fungi		Ascomycota	Proteobacteria	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mandelate catabolic process [GO:0019596]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1t9db3_d1mczi3__1	Fungi		Ascomycota	Proteobacteria	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mandelate catabolic process [GO:0019596]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1t9db3_d4jubd3__1	Fungi		Ascomycota	Proteobacteria	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mandelate catabolic process [GO:0019596]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1t9dc3_d1r9ja2__1	Fungi		Ascomycota		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1t9dd1_d1yc2d___1	Fungi		Ascomycota	Euryarchaeota	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d1t9gr__d1vl2b1__1	Metazoa		Chordata	Thermotogae	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	cytoplasm [GO:0005737]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]; argininosuccinate metabolic process [GO:0000053]; urea cycle [GO:0000050]	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	arginine biosynthetic process [GO:0006526]; argininosuccinate metabolic process [GO:0000053]; urea cycle [GO:0000050]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]	argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]
d1t9na__d4ww8b___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; chloride ion homeostasis [GO:0055064]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; chloride ion homeostasis [GO:0055064]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1t9sa__d3k3hb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytosol [GO:0005829]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1t9sa__d4ajga1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d1t9sb__d5u7da___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d1ta1b__d1c3pa___1	Metazoa		Chordata	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	metal ion binding [GO:0046872]; acetoin metabolic process [GO:0045149]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	acetoin metabolic process [GO:0045149]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	metal ion binding [GO:0046872]
d1taeb__d4ucra___1			Firmicutes	Proteobacteria	DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; base-excision repair, DNA ligation [GO:0006288]; DNA replication [GO:0006260]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	base-excision repair, DNA ligation [GO:0006288]; DNA replication [GO:0006260]		cytosol [GO:0005829]	DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]
d1taed__d3pn1a___1			Firmicutes	Proteobacteria	DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; base-excision repair, DNA ligation [GO:0006288]; DNA replication [GO:0006260]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	base-excision repair, DNA ligation [GO:0006288]; DNA replication [GO:0006260]		cytosol [GO:0005829]	DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]
d1tahb__d3d2cd___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d1tahb__d4g1fb2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1tala__d1gbla___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1tata__d4pfnb___1	Metazoa		Chordata	Apicomplexa	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d1tawa__d4yoia___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1taya__d1hfzb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]
d1taya__d3fi5b___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1tb0x__d1dcba___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1tb5b__d1xx7c1__1	Metazoa		Chordata	Euryarchaeota	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	5'-deoxynucleotidase activity [GO:0002953]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]		centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]		3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	5'-deoxynucleotidase activity [GO:0002953]
d1tb6.1_d1eq9a___1	Metazoa	Metazoa	Chordata	Arthropoda	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	serine-type endopeptidase activity [GO:0004252]
d1tb7b__d2ousa1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d1tbab2_d1vtoa1__1	Metazoa	Viridiplantae	Arthropoda	Streptophyta	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PRC1 complex [GO:0035102]; transcription factor TFIID complex [GO:0005669]; ATP binding [GO:0005524]; H4 histone acetyltransferase activity [GO:0010485]; histone acetyltransferase activity [GO:0004402]; histone acetyltransferase activity (H3-K14 specific) [GO:0036408]; protein serine/threonine kinase activity [GO:0004674]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]; transcription factor binding [GO:0008134]; ubiquitin activating enzyme activity [GO:0004839]; ubiquitin conjugating enzyme activity [GO:0061631]; cell cycle [GO:0007049]; DNA-templated transcription, initiation [GO:0006352]; histone H3-K14 acetylation [GO:0044154]; histone H4 acetylation [GO:0043967]; histone monoubiquitination [GO:0010390]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein phosphorylation [GO:0006468]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription initiation from RNA polymerase II promoter [GO:0006367]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cell cycle [GO:0007049]; DNA-templated transcription, initiation [GO:0006352]; histone H3-K14 acetylation [GO:0044154]; histone H4 acetylation [GO:0043967]; histone monoubiquitination [GO:0010390]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein phosphorylation [GO:0006468]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription initiation from RNA polymerase II promoter [GO:0006367]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PRC1 complex [GO:0035102]; transcription factor TFIID complex [GO:0005669]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; H4 histone acetyltransferase activity [GO:0010485]; histone acetyltransferase activity [GO:0004402]; histone acetyltransferase activity (H3-K14 specific) [GO:0036408]; protein serine/threonine kinase activity [GO:0004674]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]; transcription factor binding [GO:0008134]; ubiquitin activating enzyme activity [GO:0004839]; ubiquitin conjugating enzyme activity [GO:0061631]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1tbbb__d3jsib1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1tbda1_d2if9a2__1					host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; hydrolase activity [GO:0016787]; DNA replication [GO:0006260]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]	host cell nucleus [GO:0042025]		ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; hydrolase activity [GO:0016787]
d1tbgd__d4ql1a___1	Metazoa	Metazoa	Chordata	Chordata	heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; photoreceptor disc membrane [GO:0097381]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; photoreceptor disc membrane [GO:0097381]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]		histone binding [GO:0042393]; methylated histone binding [GO:0035064]
d1tbhb__d1p8rb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1tbmb__d1f0jb___1		Metazoa		Chordata		centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]		cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]		centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]		3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d1tbpa2_d3cwsd2__1	Fungi		Ascomycota	Proteobacteria	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1tbpb2_d3cwua2__1	Fungi		Ascomycota	Proteobacteria	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1tbq.2_d5dp6d___1	Metazoa		Chordata		extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1tbr.1_d1a5h.1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]; blood coagulation [GO:0007596]	apical part of cell [GO:0045177]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; phosphoprotein binding [GO:0051219]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; blood coagulation [GO:0007596]; cellular protein modification process [GO:0006464]; fibrinolysis [GO:0042730]; negative regulation of proteolysis [GO:0045861]; plasminogen activation [GO:0031639]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; proteolysis [GO:0006508]; response to hypoxia [GO:0001666]; smooth muscle cell migration [GO:0014909]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]	blood coagulation [GO:0007596]	blood coagulation [GO:0007596]; cellular protein modification process [GO:0006464]; fibrinolysis [GO:0042730]; negative regulation of proteolysis [GO:0045861]; plasminogen activation [GO:0031639]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; proteolysis [GO:0006508]; response to hypoxia [GO:0001666]; smooth muscle cell migration [GO:0014909]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]	extracellular region [GO:0005576]	apical part of cell [GO:0045177]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]	serine-type endopeptidase inhibitor activity [GO:0004867]	phosphoprotein binding [GO:0051219]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d1tbz.1_d1qa7c___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1tc8a__d1fdka___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]
d1tcaa__d4gwlb___1	Fungi	Fungi	Basidiomycota	Ascomycota	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]			triglyceride lipase activity [GO:0004806]	triglyceride lipase activity [GO:0004806]
d1tcba__d3x3hf___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]
d1tcbb__d5kwia___1	Fungi		Basidiomycota	Actinobacteria	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cell wall [GO:0005618]; extracellular region [GO:0005576]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	lipid catabolic process [GO:0016042]	glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; extracellular region [GO:0005576]	triglyceride lipase activity [GO:0004806]	diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]
d1tcfa__d1cnpb___1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]; troponin T binding [GO:0031014]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; calcium ion binding [GO:0005509]; protein N-terminus binding [GO:0047485]				cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]	calcium ion binding [GO:0005509]; troponin T binding [GO:0031014]	calcium ion binding [GO:0005509]; protein N-terminus binding [GO:0047485]
d1tcma2_d3bmva2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1tcma4_d1bglf5__1			Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	
d1tcmb1_d1okeb1__1			Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1tcmb2_d3wmsa4__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1tcmb4_d1ghoi5__1			Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	
d1tcoa__d3k7wc___1	Metazoa	Metazoa	Chordata	Chordata	calcineurin complex [GO:0005955]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynapse [GO:0098794]; sarcolemma [GO:0042383]; Schaffer collateral - CA1 synapse [GO:0098685]; calcium ion binding [GO:0005509]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; branching involved in blood vessel morphogenesis [GO:0001569]; calcineurin-NFAT signaling cascade [GO:0033173]; epithelial to mesenchymal transition [GO:0001837]; heart development [GO:0007507]; lung epithelial cell differentiation [GO:0060487]; myelination in peripheral nervous system [GO:0022011]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein import into nucleus [GO:0006606]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	branching involved in blood vessel morphogenesis [GO:0001569]; calcineurin-NFAT signaling cascade [GO:0033173]; epithelial to mesenchymal transition [GO:0001837]; heart development [GO:0007507]; lung epithelial cell differentiation [GO:0060487]; myelination in peripheral nervous system [GO:0022011]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein import into nucleus [GO:0006606]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	calcineurin complex [GO:0005955]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynapse [GO:0098794]; sarcolemma [GO:0042383]; Schaffer collateral - CA1 synapse [GO:0098685]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]	calcium ion binding [GO:0005509]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]	GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]
d1tcoc__d4lava2__1	Metazoa	Metazoa	Chordata	Chordata	calcineurin complex [GO:0005955]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynapse [GO:0098794]; sarcolemma [GO:0042383]; Schaffer collateral - CA1 synapse [GO:0098685]; calcium ion binding [GO:0005509]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; branching involved in blood vessel morphogenesis [GO:0001569]; calcineurin-NFAT signaling cascade [GO:0033173]; epithelial to mesenchymal transition [GO:0001837]; heart development [GO:0007507]; lung epithelial cell differentiation [GO:0060487]; myelination in peripheral nervous system [GO:0022011]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein import into nucleus [GO:0006606]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein-containing complex localization [GO:0031503]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	branching involved in blood vessel morphogenesis [GO:0001569]; calcineurin-NFAT signaling cascade [GO:0033173]; epithelial to mesenchymal transition [GO:0001837]; heart development [GO:0007507]; lung epithelial cell differentiation [GO:0060487]; myelination in peripheral nervous system [GO:0022011]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein import into nucleus [GO:0006606]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]	androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein-containing complex localization [GO:0031503]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	calcineurin complex [GO:0005955]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynapse [GO:0098794]; sarcolemma [GO:0042383]; Schaffer collateral - CA1 synapse [GO:0098685]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	calcium ion binding [GO:0005509]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]	ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]
d1tcra1_d2dqjh___1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	T cell receptor complex [GO:0042101]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1tcra2_d1ktdb1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	adaptive immune response [GO:0002250]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]		
d1tcrb1_d3cfkn2__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1tcuc__d4f2pa___1	Metazoa		Platyhelminthes		purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]		nucleoside metabolic process [GO:0009116]				purine-nucleoside phosphorylase activity [GO:0004731]	
d1tcxa__d5p3sa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1tcxb__d1w6ic___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1td1c__d4f3ca___1	Metazoa		Platyhelminthes		purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]		nucleoside metabolic process [GO:0009116]				purine-nucleoside phosphorylase activity [GO:0004731]	
d1td2b__d1lhpb___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; pyridoxal kinase activity [GO:0008478]; pyridoxal 5'-phosphate salvage [GO:0009443]; pyridoxal metabolic process [GO:0042817]; vitamin B6 biosynthetic process [GO:0042819]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]; pyridoxal 5'-phosphate salvage [GO:0009443]	pyridoxal 5'-phosphate salvage [GO:0009443]; pyridoxal metabolic process [GO:0042817]; vitamin B6 biosynthetic process [GO:0042819]	pyridoxal 5'-phosphate salvage [GO:0009443]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; pyridoxal kinase activity [GO:0008478]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]
d1td9b1_d1dr0b___1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	acetyl-CoA biosynthetic process [GO:0006085]	leucine biosynthetic process [GO:0009098]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	phosphate acetyltransferase activity [GO:0008959]	3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1td9d1_d1dpza___1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	acetyl-CoA biosynthetic process [GO:0006085]	leucine biosynthetic process [GO:0009098]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	phosphate acetyltransferase activity [GO:0008959]	3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1tdea2_d1gthd3__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; flavin adenine dinucleotide binding [GO:0050660]; thioredoxin-disulfide reductase activity [GO:0004791]; removal of superoxide radicals [GO:0019430]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	removal of superoxide radicals [GO:0019430]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	flavin adenine dinucleotide binding [GO:0050660]; thioredoxin-disulfide reductase activity [GO:0004791]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d1tdha2_d3jr5a1__1	Metazoa		Chordata	Firmicutes	chromosome [GO:0005694]; cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA N-glycosylase activity [GO:0019104]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; protein C-terminus binding [GO:0008022]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; depyrimidination [GO:0045008]; negative regulation of nuclease activity [GO:0032074]; nucleotide-excision repair [GO:0006289]; response to oxidative stress [GO:0006979]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; depyrimidination [GO:0045008]; negative regulation of nuclease activity [GO:0032074]; nucleotide-excision repair [GO:0006289]; response to oxidative stress [GO:0006979]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA N-glycosylase activity [GO:0019104]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; protein C-terminus binding [GO:0008022]; zinc ion binding [GO:0008270]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]
d1tdia1_d2fchc___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutathione transferase activity [GO:0004364]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1tdia1_d3zvjs1__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]	glutathione transferase activity [GO:0004364]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1tdia2_d1zl9b2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; innate immune response [GO:0045087]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; innate immune response [GO:0045087]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1tdib1_d5a5ki1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	glutathione transferase activity [GO:0004364]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d1tdja1_d1ttqb___1			Proteobacteria	Proteobacteria	amino acid binding [GO:0016597]; L-threonine ammonia-lyase activity [GO:0004794]; pyridoxal phosphate binding [GO:0030170]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; threonine catabolic process [GO:0006567]; threonine metabolic process [GO:0006566]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; threonine catabolic process [GO:0006567]; threonine metabolic process [GO:0006566]	tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; L-threonine ammonia-lyase activity [GO:0004794]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]
d1tdna2_d1ju2b2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179]	flavin adenine dinucleotide binding [GO:0050660]; mandelonitrile lyase activity [GO:0046593]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]; nitrile metabolic process [GO:0050898]	apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179]	nitrile metabolic process [GO:0050898]	extracellular region [GO:0005576]		L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]	flavin adenine dinucleotide binding [GO:0050660]; mandelonitrile lyase activity [GO:0046593]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]
d1tdoa2_d2igoe2__1	Metazoa	Fungi	Chordata	Basidiomycota	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179]		extracellular region [GO:0005576]		L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]
d1tdqa2_d5m5eb2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; perisynaptic extracellular matrix [GO:0098966]; integrin binding [GO:0005178]; cell adhesion [GO:0007155]; negative regulation of cell adhesion [GO:0007162]; nervous system development [GO:0007399]; regulation of neurogenesis [GO:0050767]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; cytokine activity [GO:0005125]; glycosphingolipid binding [GO:0043208]; growth factor activity [GO:0008083]; interleukin-2 receptor binding [GO:0005134]; kappa-type opioid receptor binding [GO:0031851]; kinase activator activity [GO:0019209]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; immune response [GO:0006955]; interleukin-2-mediated signaling pathway [GO:0038110]; leukocyte activation involved in immune response [GO:0002366]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of heart contraction [GO:0045822]; negative regulation of inflammatory response [GO:0050728]; negative regulation of lymphocyte proliferation [GO:0050672]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; response to ethanol [GO:0045471]; T cell differentiation [GO:0030217]	cell adhesion [GO:0007155]; negative regulation of cell adhesion [GO:0007162]; nervous system development [GO:0007399]; regulation of neurogenesis [GO:0050767]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; immune response [GO:0006955]; interleukin-2-mediated signaling pathway [GO:0038110]; leukocyte activation involved in immune response [GO:0002366]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of heart contraction [GO:0045822]; negative regulation of inflammatory response [GO:0050728]; negative regulation of lymphocyte proliferation [GO:0050672]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; response to ethanol [GO:0045471]; T cell differentiation [GO:0030217]	extracellular matrix [GO:0031012]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; perisynaptic extracellular matrix [GO:0098966]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	integrin binding [GO:0005178]	carbohydrate binding [GO:0030246]; cytokine activity [GO:0005125]; glycosphingolipid binding [GO:0043208]; growth factor activity [GO:0008083]; interleukin-2 receptor binding [GO:0005134]; kappa-type opioid receptor binding [GO:0031851]; kinase activator activity [GO:0019209]
d1tdqb__d2yhfa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; perisynaptic extracellular matrix [GO:0098966]; integrin binding [GO:0005178]; cell adhesion [GO:0007155]; negative regulation of cell adhesion [GO:0007162]; nervous system development [GO:0007399]; regulation of neurogenesis [GO:0050767]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]; cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	cell adhesion [GO:0007155]; negative regulation of cell adhesion [GO:0007162]; nervous system development [GO:0007399]; regulation of neurogenesis [GO:0050767]	cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	extracellular matrix [GO:0031012]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; perisynaptic extracellular matrix [GO:0098966]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	integrin binding [GO:0005178]	carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]
d1tdta__d2ic7c___1				Firmicutes	cytoplasm [GO:0005737]; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	maltose O-acetyltransferase activity [GO:0008925]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]		2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]	maltose O-acetyltransferase activity [GO:0008925]
d1tdza2_d1ee8b2__1			Firmicutes	Deinococcus-Thermus	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]			class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]
d1te0a1_d1y8ta1__1			Proteobacteria	Actinobacteria	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cellular response to antibiotic [GO:0071236]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	cellular response to antibiotic [GO:0071236]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1te0b1_d4yyxa1__1		Metazoa	Proteobacteria	Chordata	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell projection [GO:0042995]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of cell migration [GO:0030335]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]
d1te1b__d3afka1__1	Fungi	Fungi	Ascomycota	Basidiomycota	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	xylan catabolic process [GO:0045493]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d1te6a2_d3qkfg1__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	
d1te6a2_d4ihcf1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d1te6b1_d5wroa2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1teeb2_d4xl2a1__1			Actinobacteria	Firmicutes	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]	chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]			cytoplasm [GO:0005737]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1teec2_d1u0ua1__1		Viridiplantae	Actinobacteria	Streptophyta	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	biosynthetic process [GO:0009058]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	pinosylvin synthase activity [GO:0050198]
d1teec2_d2x3ea2__1			Actinobacteria	Proteobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1teed2_d1u0vb1__1		Viridiplantae	Actinobacteria	Streptophyta	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]			transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	naringenin-chalcone synthase activity [GO:0016210]
d1teed2_d4b0nb2__1			Actinobacteria		transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	biosynthetic process [GO:0009058]			transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1tegb__d1azra___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane [GO:0009535]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1teha2_d1e3la2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; all-trans retinal binding [GO:0005503]; benzaldehyde dehydrogenase [NAD(P)+] activity [GO:0019115]; ethanol binding [GO:0035276]; NAD binding [GO:0051287]; NADPH:quinone reductase activity [GO:0003960]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; quinone metabolic process [GO:1901661]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; quinone metabolic process [GO:1901661]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; all-trans retinal binding [GO:0005503]; benzaldehyde dehydrogenase [NAD(P)+] activity [GO:0019115]; ethanol binding [GO:0035276]; NAD binding [GO:0051287]; NADPH:quinone reductase activity [GO:0003960]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]
d1teia__d5jlva1__1	Viridiplantae		Streptophyta	Firmicutes	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1teie__d1epwa1__1	Viridiplantae		Streptophyta	Firmicutes	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1teih__d1un1a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	apoplast [GO:0048046]; cell wall [GO:0005618]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]; cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]		cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]		apoplast [GO:0048046]; cell wall [GO:0005618]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]
d1telb2_d1rxoh2__1		Viridiplantae	Chlorobi	Streptophyta	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1tena__d4o00b1__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; interstitial matrix [GO:0005614]; membrane [GO:0016020]; perisynaptic extracellular matrix [GO:0098966]; extracellular matrix structural constituent [GO:0005201]; syndecan binding [GO:0045545]; bud outgrowth involved in lung branching [GO:0060447]; cell adhesion [GO:0007155]; cellular protein metabolic process [GO:0044267]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin D [GO:0071305]; extracellular matrix organization [GO:0030198]; mesenchymal-epithelial cell signaling involved in prostate gland development [GO:0060739]; negative regulation of cell adhesion [GO:0007162]; neuromuscular junction development [GO:0007528]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; post-translational protein modification [GO:0043687]; prostate gland epithelium morphogenesis [GO:0060740]; response to ethanol [GO:0045471]; response to fibroblast growth factor [GO:0071774]; response to mechanical stimulus [GO:0009612]; response to wounding [GO:0009611]; wound healing [GO:0042060]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	bud outgrowth involved in lung branching [GO:0060447]; cell adhesion [GO:0007155]; cellular protein metabolic process [GO:0044267]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin D [GO:0071305]; extracellular matrix organization [GO:0030198]; mesenchymal-epithelial cell signaling involved in prostate gland development [GO:0060739]; negative regulation of cell adhesion [GO:0007162]; neuromuscular junction development [GO:0007528]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; post-translational protein modification [GO:0043687]; prostate gland epithelium morphogenesis [GO:0060740]; response to ethanol [GO:0045471]; response to fibroblast growth factor [GO:0071774]; response to mechanical stimulus [GO:0009612]; response to wounding [GO:0009611]; wound healing [GO:0042060]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; interstitial matrix [GO:0005614]; membrane [GO:0016020]; perisynaptic extracellular matrix [GO:0098966]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	extracellular matrix structural constituent [GO:0005201]; syndecan binding [GO:0045545]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1tepc__d1gz9a___1		Viridiplantae		Streptophyta		carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]
d1tepd__d5ewsg___1		Metazoa		Chordata		carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]						carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d1teth1_d4wfef1__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]; identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]; cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]	killing of cells of other organism [GO:0031640]	cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]	extracellular region [GO:0005576]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]	toxin activity [GO:0090729]	identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]
d1tetl1_d1ar1d___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	toxin activity [GO:0090729]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1tetl1_d1rmfh2__1			Proteobacteria		extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]		killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]		toxin activity [GO:0090729]	
d1tewa__d123la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1tezb1_d2wb2a2__1		Metazoa	Cyanobacteria	Arthropoda	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	nucleotide binding [GO:0000166]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]				deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d1tezd2_d4i6ja1__1		Metazoa	Cyanobacteria	Chordata	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; FAD binding [GO:0071949]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; phosphatase binding [GO:0019902]; photoreceptor activity [GO:0009881]; protein kinase binding [GO:0019901]; single-stranded DNA binding [GO:0003697]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; protein import into nucleus [GO:0006606]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-chromophore linkage [GO:0018298]; protein import into nucleus [GO:0006606]; regulation of circadian rhythm [GO:0042752]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; FAD binding [GO:0071949]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; phosphatase binding [GO:0019902]; photoreceptor activity [GO:0009881]; protein kinase binding [GO:0019901]; single-stranded DNA binding [GO:0003697]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1tf0a3_d5otbb2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1tf1a1_d1stzb2__1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]	cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]
d1tf1d1_d3nhqf2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d1tf4b1_d1gaha___1		Fungi	Actinobacteria	Ascomycota	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]
d1tf5a4_d3fhta1__1		Metazoa	Firmicutes	Chordata	cell envelope Sec protein transport complex [GO:0031522]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; ATPase-coupled protein transmembrane transporter activity [GO:0015462]; metal ion binding [GO:0046872]; intracellular protein transmembrane transport [GO:0065002]; protein import [GO:0017038]; protein targeting [GO:0006605]; protein transport by the Sec complex [GO:0043952]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]	intracellular protein transmembrane transport [GO:0065002]; protein import [GO:0017038]; protein targeting [GO:0006605]; protein transport by the Sec complex [GO:0043952]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]	cell envelope Sec protein transport complex [GO:0031522]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleus [GO:0005634]	ATPase-coupled protein transmembrane transporter activity [GO:0015462]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]
d1tf7d1_d1w36f2__1			Cyanobacteria	Proteobacteria	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; exodeoxyribonuclease V complex [GO:0009338]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA translocase activity [GO:0015616]; DNA-dependent ATPase activity [GO:0008094]; endodeoxyribonuclease activity [GO:0004520]; exodeoxyribonuclease V activity [GO:0008854]; magnesium ion binding [GO:0000287]; clearance of foreign intracellular DNA [GO:0044355]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; recombinational repair [GO:0000725]; response to radiation [GO:0009314]	circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	clearance of foreign intracellular DNA [GO:0044355]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; recombinational repair [GO:0000725]; response to radiation [GO:0009314]		cytosol [GO:0005829]; exodeoxyribonuclease V complex [GO:0009338]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA helicase activity [GO:0003678]; DNA translocase activity [GO:0015616]; endodeoxyribonuclease activity [GO:0004520]; exodeoxyribonuclease V activity [GO:0008854]; magnesium ion binding [GO:0000287]
d1tf7e2_d2qe7c2__1			Cyanobacteria	Firmicutes	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	ATP synthesis coupled proton transport [GO:0015986]		plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1tfea__d1xb2b2__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; translation elongation factor activity [GO:0003746]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]		mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1tfmb1_d4lo0a2__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]				carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	
d1tfra1_d1ut8a1__1					5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; exonuclease activity [GO:0004527]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, Okazaki fragment processing [GO:0033567]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; exodeoxyribonuclease activity [GO:0004529]; metal ion binding [GO:0046872]; DNA replication, Okazaki fragment processing [GO:0033567]; viral DNA genome replication [GO:0039693]	DNA replication, Okazaki fragment processing [GO:0033567]	DNA replication, Okazaki fragment processing [GO:0033567]; viral DNA genome replication [GO:0039693]			5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; exonuclease activity [GO:0004527]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; exodeoxyribonuclease activity [GO:0004529]; metal ion binding [GO:0046872]
d1tfua__d3innc1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]; pantothenate biosynthetic process [GO:0015940]	coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	pantothenate biosynthetic process [GO:0015940]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]
d1tfwb1_d1px5b1__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 2'-5'-oligoadenylate synthetase activity [GO:0001730]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; purine nucleotide biosynthetic process [GO:0006164]; regulation of ribonuclease activity [GO:0060700]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; purine nucleotide biosynthetic process [GO:0006164]; regulation of ribonuclease activity [GO:0060700]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	2'-5'-oligoadenylate synthetase activity [GO:0001730]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]
d1tfya1_d4k8vc2__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immune response [GO:0050776]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]; regulation of type I interferon production [GO:0032479]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immune response [GO:0050776]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]; regulation of type I interferon production [GO:0032479]		cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]
d1tfyb1_d3c66b1__1		Fungi	Euryarchaeota	Ascomycota	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]		mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d1tfyd1_d4rwqa2__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 2'-5'-oligoadenylate synthetase activity [GO:0001730]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; purine nucleotide biosynthetic process [GO:0006164]; regulation of ribonuclease activity [GO:0060700]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; purine nucleotide biosynthetic process [GO:0006164]; regulation of ribonuclease activity [GO:0060700]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	2'-5'-oligoadenylate synthetase activity [GO:0001730]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]
d1tg1a__d3bjwf___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]
d1tg7a3_d3i3dc1__1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; extracellular space [GO:0005615]; beta-galactosidase activity [GO:0004565]; galactose binding [GO:0005534]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	beta-galactosidase complex [GO:0009341]	beta-galactosidase activity [GO:0004565]; galactose binding [GO:0005534]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1tg7a5_d3f55b___1	Fungi		Ascomycota		extracellular region [GO:0005576]; extracellular space [GO:0005615]; beta-galactosidase activity [GO:0004565]; galactose binding [GO:0005534]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]		lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		beta-galactosidase activity [GO:0004565]; galactose binding [GO:0005534]	
d1tg8a1_d2r29a___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; serine-type peptidase activity [GO:0008236]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; serine-type peptidase activity [GO:0008236]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1tg9a__d4z0qa___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1tgca__d3odfa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1tgca__d4q7xa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	azurophil granule lumen [GO:0035578]; extracellular space [GO:0005615]; heparin binding [GO:0008201]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	azurophil granule lumen [GO:0035578]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	heparin binding [GO:0008201]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1tgeb1_d1bfta___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; serine-type peptidase activity [GO:0008236]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; serine-type peptidase activity [GO:0008236]	actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]
d1tgeb1_d5kvde___1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; serine-type peptidase activity [GO:0008236]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1tgha1_d3cvsc2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; male pronucleus [GO:0001940]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; transcriptional preinitiation complex [GO:0097550]; aryl hydrocarbon receptor binding [GO:0017162]; core promoter binding [GO:0001047]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; proximal promoter sequence-specific DNA binding [GO:0000987]; repressing transcription factor binding [GO:0070491]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II repressing transcription factor binding [GO:0001103]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIB-class transcription factor binding [GO:0001093]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; snRNA transcription by RNA polymerase II [GO:0042795]; spermatogenesis [GO:0007283]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; spermatogenesis [GO:0007283]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]; viral process [GO:0016032]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; male pronucleus [GO:0001940]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional preinitiation complex [GO:0097550]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	aryl hydrocarbon receptor binding [GO:0017162]; core promoter binding [GO:0001047]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; proximal promoter sequence-specific DNA binding [GO:0000987]; repressing transcription factor binding [GO:0070491]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II repressing transcription factor binding [GO:0001103]; TFIIB-class transcription factor binding [GO:0001093]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1tgha2_d3d4va2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; male pronucleus [GO:0001940]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; transcriptional preinitiation complex [GO:0097550]; aryl hydrocarbon receptor binding [GO:0017162]; core promoter binding [GO:0001047]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; proximal promoter sequence-specific DNA binding [GO:0000987]; repressing transcription factor binding [GO:0070491]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II repressing transcription factor binding [GO:0001103]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIB-class transcription factor binding [GO:0001093]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; snRNA transcription by RNA polymerase II [GO:0042795]; spermatogenesis [GO:0007283]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; spermatogenesis [GO:0007283]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]; viral process [GO:0016032]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	cytoplasm [GO:0005737]; female pronucleus [GO:0001939]; male pronucleus [GO:0001940]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional preinitiation complex [GO:0097550]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	aryl hydrocarbon receptor binding [GO:0017162]; core promoter binding [GO:0001047]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; proximal promoter sequence-specific DNA binding [GO:0000987]; repressing transcription factor binding [GO:0070491]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II repressing transcription factor binding [GO:0001103]; TFIIB-class transcription factor binding [GO:0001093]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1tgma__d1fv0b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1tgta__d5jbcs___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]
d1tgta__d5q0da___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d1tgva__d4ts3e___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]
d1tgzb__d3zrca___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]	ubiquitin protein ligase binding [GO:0031625]
d1th0b__d5aeki___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein domain specific binding [GO:0019904]; SUMO-specific endopeptidase activity [GO:0070139]; SUMO-specific isopeptidase activity [GO:0070140]; dorsal/ventral axis specification [GO:0009950]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; labyrinthine layer development [GO:0060711]; mRNA transport [GO:0051028]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of DNA endoreduplication [GO:0032875]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of Wnt signaling pathway [GO:0030111]; spongiotrophoblast layer development [GO:0060712]; trophoblast giant cell differentiation [GO:0060707]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	dorsal/ventral axis specification [GO:0009950]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; labyrinthine layer development [GO:0060711]; mRNA transport [GO:0051028]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of DNA endoreduplication [GO:0032875]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of Wnt signaling pathway [GO:0030111]; spongiotrophoblast layer development [GO:0060712]; trophoblast giant cell differentiation [GO:0060707]; Wnt signaling pathway [GO:0016055]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	protein domain specific binding [GO:0019904]; SUMO-specific endopeptidase activity [GO:0070139]; SUMO-specific isopeptidase activity [GO:0070140]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d1th7a1_d1h64x___1			Crenarchaeota	Euryarchaeota								
d1th7d2_d1i4ky___1			Crenarchaeota	Euryarchaeota								
d1th7f2_d1vu3v___1			Crenarchaeota									
d1th7h2_d1h64w___1			Crenarchaeota	Euryarchaeota								
d1th7i2_d1n9rf___1		Fungi	Crenarchaeota	Ascomycota		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]
d1th7i2_d1vu3f___1			Crenarchaeota									
d1th7m2_d1i81e___1			Crenarchaeota	Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]		
d1th7n2_d1lojg1__1			Crenarchaeota	Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]		
d1thaa__d2h6ud___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1thba__d1ltwa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1thba__d2d2mc___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1thbc__d2yrsb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1thca__d3imwa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1thdc1_d2f08c___1		Metazoa		Arthropoda	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	
d1thea__d2frqa___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; melanosome [GO:0042470]; mitochondrion [GO:0005739]; sarcolemma [GO:0042383]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; kininogen binding [GO:0030984]; peptide binding [GO:0042277]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; autophagy [GO:0006914]; cellular response to mechanical stimulus [GO:0071260]; negative regulation of cell death [GO:0060548]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of catalytic activity [GO:0050790]; response to amine [GO:0014075]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to interleukin-4 [GO:0070670]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to wounding [GO:0009611]; skeletal muscle tissue development [GO:0007519]; spermatogenesis [GO:0007283]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	autophagy [GO:0006914]; cellular response to mechanical stimulus [GO:0071260]; negative regulation of cell death [GO:0060548]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of catalytic activity [GO:0050790]; response to amine [GO:0014075]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to interleukin-4 [GO:0070670]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to wounding [GO:0009611]; skeletal muscle tissue development [GO:0007519]; spermatogenesis [GO:0007283]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; melanosome [GO:0042470]; mitochondrion [GO:0005739]; sarcolemma [GO:0042383]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; kininogen binding [GO:0030984]; peptide binding [GO:0042277]; protein-containing complex binding [GO:0044877]; protein self-association [GO:0043621]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d1thja__d3v4ea___1			Euryarchaeota	Firmicutes	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	acetyltransferase activity [GO:0016407]					bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	acetyltransferase activity [GO:0016407]
d1thjc__d4kpxa2__1			Euryarchaeota	Proteobacteria	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d1thka__d1rj6a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	integral component of membrane [GO:0016021]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon dioxide transport [GO:0015670]; regulation of pH [GO:0006885]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbon dioxide transport [GO:0015670]; regulation of pH [GO:0006885]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1thla__d3flfa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1thna1_d4o04a___1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; sigma factor antagonist activity [GO:0016989]; asexual sporulation [GO:0030436]; negative regulation of sporulation resulting in formation of a cellular spore [GO:0042174]; negative regulation of transcription, DNA-templated [GO:0045892]; sporulation resulting in formation of a cellular spore [GO:0030435]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	asexual sporulation [GO:0030436]; negative regulation of sporulation resulting in formation of a cellular spore [GO:0042174]; negative regulation of transcription, DNA-templated [GO:0045892]; sporulation resulting in formation of a cellular spore [GO:0030435]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; sigma factor antagonist activity [GO:0016989]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1thnb__d1vc1a___1			Firmicutes	Thermotogae	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; sigma factor antagonist activity [GO:0016989]; asexual sporulation [GO:0030436]; negative regulation of sporulation resulting in formation of a cellular spore [GO:0042174]; negative regulation of transcription, DNA-templated [GO:0045892]; sporulation resulting in formation of a cellular spore [GO:0030435]	anti-sigma factor antagonist activity [GO:0043856]	asexual sporulation [GO:0030436]; negative regulation of sporulation resulting in formation of a cellular spore [GO:0042174]; negative regulation of transcription, DNA-templated [GO:0045892]; sporulation resulting in formation of a cellular spore [GO:0030435]				ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; sigma factor antagonist activity [GO:0016989]	anti-sigma factor antagonist activity [GO:0043856]
d1thnc1_d2xdsa___1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; sigma factor antagonist activity [GO:0016989]; asexual sporulation [GO:0030436]; negative regulation of sporulation resulting in formation of a cellular spore [GO:0042174]; negative regulation of transcription, DNA-templated [GO:0045892]; sporulation resulting in formation of a cellular spore [GO:0030435]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	asexual sporulation [GO:0030436]; negative regulation of sporulation resulting in formation of a cellular spore [GO:0042174]; negative regulation of transcription, DNA-templated [GO:0045892]; sporulation resulting in formation of a cellular spore [GO:0030435]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; sigma factor antagonist activity [GO:0016989]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1thoa__d4zl7a___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; periplasmic space [GO:0042597]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	protein disulfide oxidoreductase activity [GO:0015035]
d1ths.1_d5eqra1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; transformation of host cell by virus [GO:0019087]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	transformation of host cell by virus [GO:0019087]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d1thva__d4bcta___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasmic vesicle [GO:0031410]	extracellular region [GO:0005576]; defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]		defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]	cytoplasmic vesicle [GO:0031410]	extracellular region [GO:0005576]		
d1thwa__d5lh0a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]			cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]		
d1thxa__d2xpea___1			Cyanobacteria	Proteobacteria	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	protein disulfide oxidoreductase activity [GO:0015035]	thioredoxin peroxidase activity [GO:0008379]
d1ti2d2_d1b0vd___1				Proteobacteria		3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1ti2d2_d1kqfb1__1				Proteobacteria		formate dehydrogenase complex [GO:0009326]; membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (cytochrome-c-553) activity [GO:0047111]; formate dehydrogenase (NAD+) activity [GO:0008863]; formate dehydrogenase (quinone) activity [GO:0036397]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; selenium binding [GO:0008430]; anaerobic respiration [GO:0009061]; formate oxidation [GO:0015944]		anaerobic respiration [GO:0009061]; formate oxidation [GO:0015944]		formate dehydrogenase complex [GO:0009326]; membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (cytochrome-c-553) activity [GO:0047111]; formate dehydrogenase (NAD+) activity [GO:0008863]; formate dehydrogenase (quinone) activity [GO:0036397]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; selenium binding [GO:0008430]
d1ti2g1_d5kiya1__1		Metazoa		Chordata		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1ti2i1_d5ftjc1__1		Metazoa		Chordata		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1ti2k1_d1uhe.1__1				Proteobacteria		cytoplasm [GO:0005737]; aspartate 1-decarboxylase activity [GO:0004068]; alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]		alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]		cytoplasm [GO:0005737]		aspartate 1-decarboxylase activity [GO:0004068]
d1ti2l2_d1gt8c5__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]		beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d1ti4a1_d1e5vc1__1				Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]
d1ti4a1_d1s3sf1__1		Metazoa		Chordata		ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1ti4a2_d1g8ke2__1				Proteobacteria		3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]						3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]
d1ti4c1_d4klnb1__1		Metazoa		Chordata		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1ti4e1_d3ias34__1				Deinococcus-Thermus		plasma membrane [GO:0005886]; quinone binding [GO:0048038]				plasma membrane [GO:0005886]		quinone binding [GO:0048038]
d1ti4h1_d3rkpa3__1				Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]				cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]		metal ion binding [GO:0046872]
d1ti4h2_d1fxrb___1				Proteobacteria		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]						4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]
d1ti4i1_d5ftka1__1		Metazoa		Chordata		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1ti6e1_d3ir5a2__1				Proteobacteria		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]
d1ti6i1_d1e61c1__1				Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]
d1ti6i2_d3i9v33__1				Deinococcus-Thermus		plasma membrane [GO:0005886]; quinone binding [GO:0048038]				plasma membrane [GO:0005886]		quinone binding [GO:0048038]
d1ti6j1_d2pz4a1__1												
d1ti6j2_d5bysa2__1				Firmicutes		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]						4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]
d1ti6k1_d3hu2a1__1		Metazoa		Chordata		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1ti6l1_d3rkpa1__1				Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]				cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]		metal ion binding [GO:0046872]
d1tiba__d2ix9a___1	Fungi	Fungi	Ascomycota	Ascomycota	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]; cell wall macromolecule catabolic process [GO:0016998]; cellulose catabolic process [GO:0030245]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	lipid catabolic process [GO:0016042]	cellulose catabolic process [GO:0030245]; cell wall macromolecule catabolic process [GO:0016998]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	triglyceride lipase activity [GO:0004806]	cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]
d1tila__d3owda___1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; sigma factor antagonist activity [GO:0016989]; asexual sporulation [GO:0030436]; negative regulation of sporulation resulting in formation of a cellular spore [GO:0042174]; negative regulation of transcription, DNA-templated [GO:0045892]; sporulation resulting in formation of a cellular spore [GO:0030435]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	asexual sporulation [GO:0030436]; negative regulation of sporulation resulting in formation of a cellular spore [GO:0042174]; negative regulation of transcription, DNA-templated [GO:0045892]; sporulation resulting in formation of a cellular spore [GO:0030435]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; sigma factor antagonist activity [GO:0016989]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1tima__d1ssgb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytosol [GO:0005829]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]
d1timb__d4g1kc___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	triose-phosphate isomerase activity [GO:0004807]
d1tioa__d4q7ya___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	azurophil granule lumen [GO:0035578]; extracellular space [GO:0005615]; heparin binding [GO:0008201]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	azurophil granule lumen [GO:0035578]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	heparin binding [GO:0008201]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1tita__d4f58n1__1	Metazoa		Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	
d1tiwa2_d4jnza2__1			Proteobacteria	Proteobacteria	cytoplasmic side of plasma membrane [GO:0009898]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]; proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	cytoplasmic side of plasma membrane [GO:0009898]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]; proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	cytoplasmic side of plasma membrane [GO:0009898]	cytoplasmic side of plasma membrane [GO:0009898]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]
d1tj3a__d4navd___1			Cyanobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]; sucrose biosynthetic process [GO:0005986]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	sucrose biosynthetic process [GO:0005986]	lipopolysaccharide biosynthetic process [GO:0009103]			magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1tj4a__d3qu2c___1			Cyanobacteria	Bacteroidetes	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]; sucrose biosynthetic process [GO:0005986]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	sucrose biosynthetic process [GO:0005986]				magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]
d1tj5a__d3e8md___1			Cyanobacteria	Bacteroidetes	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]; sucrose biosynthetic process [GO:0005986]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	sucrose biosynthetic process [GO:0005986]	lipopolysaccharide biosynthetic process [GO:0009103]			magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d1tjda1_d1ev4a2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]; aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]
d1tjea1_d5ee9a2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of response to salt stress [GO:1901001]; response to cadmium ion [GO:0046686]; response to salt stress [GO:0009651]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	negative regulation of defense response to bacterium [GO:1900425]; negative regulation of response to salt stress [GO:1901001]; response to cadmium ion [GO:0046686]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]
d1tjgh1_d2pcpa1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	
d1tjgh1_d5d6ca2__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	
d1tjgh2_d3p73a2__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	protein homodimerization activity [GO:0042803]
d1tjhh2_d4ll9a2__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; HLA-A specific inhibitory MHC class I receptor activity [GO:0030107]; HLA-B specific inhibitory MHC class I receptor activity [GO:0030109]; MHC class I protein binding [GO:0042288]; MHC class I receptor activity [GO:0032393]; MHC class Ib protein binding [GO:0023029]; MHC class Ib protein complex binding [GO:0023025]; MHC class Ib receptor activity [GO:0032394]; protein homodimerization activity [GO:0042803]; protein phosphatase 1 binding [GO:0008157]; SH2 domain binding [GO:0042169]; adaptive immune response [GO:0002250]; cellular response to lipopolysaccharide [GO:0071222]; defense response to virus [GO:0051607]; dendritic cell differentiation [GO:0097028]; Fc receptor mediated inhibitory signaling pathway [GO:0002774]; immune response-inhibiting cell surface receptor signaling pathway [GO:0002767]; interferon-gamma production [GO:0032609]; interferon-gamma secretion [GO:0072643]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of cell cycle [GO:0045786]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of endocytosis [GO:0045806]; negative regulation of interferon-beta secretion [GO:0035548]; negative regulation of interferon-gamma biosynthetic process [GO:0045077]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 secretion [GO:2001180]; negative regulation of interleukin-12 secretion [GO:2001183]; negative regulation of mononuclear cell proliferation [GO:0032945]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of osteoclast development [GO:2001205]; negative regulation of serotonin secretion [GO:0014063]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytolysis [GO:0045919]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gamma-delta T cell activation involved in immune response [GO:2001193]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor internalization [GO:0031623]; regulation of immune response [GO:0050776]; response to virus [GO:0009615]; signal transduction [GO:0007165]; T cell proliferation involved in immune response [GO:0002309]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; cellular response to lipopolysaccharide [GO:0071222]; defense response to virus [GO:0051607]; dendritic cell differentiation [GO:0097028]; Fc receptor mediated inhibitory signaling pathway [GO:0002774]; immune response-inhibiting cell surface receptor signaling pathway [GO:0002767]; interferon-gamma production [GO:0032609]; interferon-gamma secretion [GO:0072643]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of cell cycle [GO:0045786]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of endocytosis [GO:0045806]; negative regulation of interferon-beta secretion [GO:0035548]; negative regulation of interferon-gamma biosynthetic process [GO:0045077]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 secretion [GO:2001180]; negative regulation of interleukin-12 secretion [GO:2001183]; negative regulation of mononuclear cell proliferation [GO:0032945]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of osteoclast development [GO:2001205]; negative regulation of serotonin secretion [GO:0014063]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytolysis [GO:0045919]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gamma-delta T cell activation involved in immune response [GO:2001193]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor internalization [GO:0031623]; regulation of immune response [GO:0050776]; response to virus [GO:0009615]; signal transduction [GO:0007165]; T cell proliferation involved in immune response [GO:0002309]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	structural molecule activity [GO:0005198]	HLA-A specific inhibitory MHC class I receptor activity [GO:0030107]; HLA-B specific inhibitory MHC class I receptor activity [GO:0030109]; MHC class Ib protein binding [GO:0023029]; MHC class Ib protein complex binding [GO:0023025]; MHC class Ib receptor activity [GO:0032394]; MHC class I protein binding [GO:0042288]; MHC class I receptor activity [GO:0032393]; protein homodimerization activity [GO:0042803]; protein phosphatase 1 binding [GO:0008157]; SH2 domain binding [GO:0042169]
d1tjhl1_d5d5md1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1tjih2_d2oi9c___1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	T cell receptor complex [GO:0042101]	structural molecule activity [GO:0005198]	
d1tjih2_d4ydjb2__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1tjil2_d1fq9c1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	structural molecule activity [GO:0005198]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]
d1tjil2_d3tm6d1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1tjma1_d2uzpa___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	calyx of Held [GO:0044305]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; presynaptic cytosol [GO:0099523]; synaptic membrane [GO:0097060]; ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; zinc ion binding [GO:0008270]; chemical synaptic transmission [GO:0007268]; chemosensory behavior [GO:0007635]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; platelet activation [GO:0030168]; positive regulation of mismatch repair [GO:0032425]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of phagocytosis [GO:0050764]; regulation of response to food [GO:0032095]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to morphine [GO:0043278]; response to pain [GO:0048265]; response to psychosocial stress [GO:1990911]; rhythmic process [GO:0048511]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	chemical synaptic transmission [GO:0007268]; chemosensory behavior [GO:0007635]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; platelet activation [GO:0030168]; positive regulation of mismatch repair [GO:0032425]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of phagocytosis [GO:0050764]; regulation of response to food [GO:0032095]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to morphine [GO:0043278]; response to pain [GO:0048265]; response to psychosocial stress [GO:1990911]; rhythmic process [GO:0048511]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	calyx of Held [GO:0044305]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; presynaptic cytosol [GO:0099523]; synaptic membrane [GO:0097060]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]	ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270]
d1tjpb__d1j0ed___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310]	tryptophan biosynthetic process [GO:0000162]	amine catabolic process [GO:0009310]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]
d1tjta2_d2wa7a2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d1tjvc__d1yfea___1	Metazoa		Chordata	Proteobacteria	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle enzyme complex [GO:0045239]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]	fumarate hydratase activity [GO:0004333]
d1tjxa1_d1bcia___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; calcium-dependent phospholipid binding [GO:0005544]; lysophospholipase activity [GO:0004622]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; cardiolipin acyl-chain remodeling [GO:0035965]; cellular response to antibiotic [GO:0071236]; glycerophospholipid catabolic process [GO:0046475]; icosanoid biosynthetic process [GO:0046456]; icosanoid metabolic process [GO:0006690]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; platelet activating factor biosynthetic process [GO:0006663]; regulation of cell population proliferation [GO:0042127]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; cardiolipin acyl-chain remodeling [GO:0035965]; cellular response to antibiotic [GO:0071236]; glycerophospholipid catabolic process [GO:0046475]; icosanoid biosynthetic process [GO:0046456]; icosanoid metabolic process [GO:0006690]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; platelet activating factor biosynthetic process [GO:0006663]; regulation of cell population proliferation [GO:0042127]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; lysophospholipase activity [GO:0004622]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]
d1tk0b__d1erwa___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d1tk6a__d1xmga___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1tk6d__d1mhzb___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	methane monooxygenase activity [GO:0015049]; methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]	methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	methane monooxygenase activity [GO:0015049]
d1tk8b__d2vcvb1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	glutathione transferase activity [GO:0004364]
d1tkaa3_d2c3ma3__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	pentose-phosphate shunt [GO:0006098]	electron transport chain [GO:0022900]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d1tkab1_d1b0pb1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	pentose-phosphate shunt [GO:0006098]	electron transport chain [GO:0022900]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d1tkab2_d1powb3__1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d1tkbb1_d1b0pb2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	pentose-phosphate shunt [GO:0006098]	electron transport chain [GO:0022900]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d1tkbb2_d3exgt1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	pentose-phosphate shunt [GO:0006098]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1tkbb3_d1um9d2__1	Fungi		Ascomycota	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]
d1tkdb__d1nw2a___1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	protein disulfide oxidoreductase activity [GO:0015035]
d1tkga2_d1nyqb3__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]
d1tkja__d1zg8a___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1tkka1_d4dhgd2__1			Firmicutes	Actinobacteria	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	metal ion binding [GO:0046872]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]				metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	metal ion binding [GO:0046872]
d1tkkb2_d3ujea1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1tkkc1_d3qtpb2__1			Firmicutes		metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	glycolytic process [GO:0006096]		phosphopyruvate hydratase complex [GO:0000015]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1tkke1_d3zlfc2__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	glycolytic process [GO:0006096]; pathogenesis [GO:0009405]		cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1tkke2_d2p8ca1__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]; peptide metabolic process [GO:0006518]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	peptide metabolic process [GO:0006518]			metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]
d1tkkg2_d2chra2__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]			metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d1tkkg2_d4a6gc1__1			Firmicutes	Actinobacteria	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	menaquinone biosynthetic process [GO:0009234]			metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d1tkkh2_d5eu9c1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1tkla__d5eo6a___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; coproporphyrinogen oxidase activity [GO:0004109]; protein homodimerization activity [GO:0042803]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	coproporphyrinogen oxidase activity [GO:0004109]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]		coproporphyrinogen oxidase activity [GO:0004109]; protein homodimerization activity [GO:0042803]	coproporphyrinogen oxidase activity [GO:0004109]
d1tkna__d4yn0b___1	Metazoa	Metazoa	Chordata	Chordata	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; growth cone [GO:0030426]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; locomotory behavior [GO:0007626]; long-term synaptic potentiation [GO:0060291]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of protein binding [GO:0043393]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid-beta clearance [GO:1900221]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; locomotory behavior [GO:0007626]; long-term synaptic potentiation [GO:0060291]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of protein binding [GO:0043393]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi lumen [GO:0005796]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; growth cone [GO:0030426]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synaptic vesicle [GO:0008021]	acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]	acetylcholine receptor binding [GO:0033130]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]
d1tkob__d1uzrc___1			Euryarchaeota	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1tkoc__d5lbhk___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1tkpb__d1afrb___1		Viridiplantae	Euryarchaeota	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]; cytoplasm [GO:0005737]	chloroplast [GO:0009507]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d1tkpb__d5jaca___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1tkpc__d1jtsa___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1tkpc__d3r2oa___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1tl0m__d5d3da1__1				Firmicutes		extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]		
d1tl4a__d1sb6a___1	Metazoa		Chordata	Cyanobacteria	cell [GO:0005623]; cytosol [GO:0005829]; ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper ion binding [GO:0005507]; copper-dependent protein binding [GO:0032767]; metallochaperone activity [GO:0016530]; cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	copper ion binding [GO:0005507]; metal ion transport [GO:0030001]	cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	metal ion transport [GO:0030001]	cell [GO:0005623]; cytosol [GO:0005829]		ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; metallochaperone activity [GO:0016530]	copper ion binding [GO:0005507]
d1tlda__d1te0a2__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1tlfc__d2o20h___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]	protein-DNA complex [GO:0032993]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]	DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1tllb3_d1ddga2__1	Metazoa		Chordata	Proteobacteria	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]; ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]	ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]
d1tllb3_d5vw7a2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]; ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]		azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]	chloroplast [GO:0009507]	ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1tloa__d2fuda___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]; aging [GO:0007568]; brain development [GO:0007420]; cellular response to hydrogen peroxide [GO:0070301]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of vascular permeability [GO:0043117]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; response to angiotensin [GO:1990776]; response to arsenic-containing substance [GO:0046685]; self proteolysis [GO:0097264]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	aging [GO:0007568]; brain development [GO:0007420]; cellular response to hydrogen peroxide [GO:0070301]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of vascular permeability [GO:0043117]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; response to angiotensin [GO:1990776]; response to arsenic-containing substance [GO:0046685]; self proteolysis [GO:0097264]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d1tlpe__d1pwvb2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]		negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d1tlta2_d1znqr2__1		Metazoa	Proteobacteria	Chordata	oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]		antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	oxidoreductase activity [GO:0016491]	aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]
d1tm2a__d1dbpa___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; periplasmic space [GO:0042597]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; monosaccharide binding [GO:0048029]; D-ribose transmembrane transport [GO:0015752]; positive chemotaxis [GO:0050918]		D-ribose transmembrane transport [GO:0015752]; positive chemotaxis [GO:0050918]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; periplasmic space [GO:0042597]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]		monosaccharide binding [GO:0048029]
d1tm4i__d3rdzd___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1tm5i__d3rdya___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	serine-type endopeptidase inhibitor activity [GO:0004867]; response to wounding [GO:0009611]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	response to wounding [GO:0009611]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1tme.1_d5w3eb___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host mRNA export from nucleus [GO:0039522]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host mRNA export from nucleus [GO:0039522]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	
d1tmha__d2btma___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1tmhb__d5cssb___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1tmla__d3a64a___1		Fungi	Actinobacteria	Basidiomycota	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1tmt.1_d1c2ea___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1tn7a__d3e37a___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]; protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]; protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]
d1tn8b__d1h37c2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1tn8b__d1tnyh___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1tnbb__d1ft2b___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1tndb1_d3c14c2__1	Metazoa	Metazoa	Chordata	Chordata	G protein-coupled receptor complex [GO:0097648]; heterotrimeric G-protein complex [GO:0005834]; photoreceptor connecting cilium [GO:0032391]; photoreceptor disc membrane [GO:0097381]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment membrane [GO:0042622]; acyl binding [GO:0000035]; G protein-coupled receptor binding [GO:0001664]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; detection of light stimulus involved in visual perception [GO:0050908]; eye photoreceptor cell development [GO:0042462]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; phototransduction [GO:0007602]; phototransduction, visible light [GO:0007603]; response to light stimulus [GO:0009416]; retina development in camera-type eye [GO:0060041]; sensory perception of umami taste [GO:0050917]	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; detection of light stimulus involved in visual perception [GO:0050908]; eye photoreceptor cell development [GO:0042462]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; phototransduction [GO:0007602]; phototransduction, visible light [GO:0007603]; response to light stimulus [GO:0009416]; retina development in camera-type eye [GO:0060041]; sensory perception of umami taste [GO:0050917]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	G protein-coupled receptor complex [GO:0097648]; heterotrimeric G-protein complex [GO:0005834]; photoreceptor connecting cilium [GO:0032391]; photoreceptor disc membrane [GO:0097381]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment membrane [GO:0042622]	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	acyl binding [GO:0000035]; GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]	adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d1tnga__d3zz3b1__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1tnia__d2qaab___1	Metazoa		Chordata	Actinobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d1tnka__d3v12a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1tnna__d2fgwh2__1	Metazoa		Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	
d1tnof__d4gaxa1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	amorpha-4,11-diene synthase activity [GO:0034006]; magnesium ion binding [GO:0000287]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]		CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]		CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	amorpha-4,11-diene synthase activity [GO:0034006]; magnesium ion binding [GO:0000287]
d1tnoh__d1h35a2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1tnpa__d4yi9a___1	Metazoa	Metazoa	Chordata	Chordata	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; calcium ion binding [GO:0005509]; phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	troponin complex [GO:0005861]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]
d1tnqa__d3ko0i___1	Metazoa	Metazoa	Chordata	Chordata	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	troponin complex [GO:0005861]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d1tnub__d1h3bc2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1tnuh__d1qsjc___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	extracellular space [GO:0005615]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; cofactor binding [GO:0048037]; endopeptidase inhibitor activity [GO:0004866]; lipid binding [GO:0008289]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; fatty acid metabolic process [GO:0006631]; inflammatory response [GO:0006954]; positive regulation of developmental growth [GO:0048639]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of protein phosphorylation [GO:0001934]; regulation of triglyceride biosynthetic process [GO:0010866]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to glucocorticoid [GO:0051384]; response to magnesium ion [GO:0032026]; response to progesterone [GO:0032570]; tolerance induction [GO:0002507]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; fatty acid metabolic process [GO:0006631]; inflammatory response [GO:0006954]; positive regulation of developmental growth [GO:0048639]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of protein phosphorylation [GO:0001934]; regulation of triglyceride biosynthetic process [GO:0010866]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to glucocorticoid [GO:0051384]; response to magnesium ion [GO:0032026]; response to progesterone [GO:0032570]; tolerance induction [GO:0002507]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	extracellular space [GO:0005615]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; cofactor binding [GO:0048037]; endopeptidase inhibitor activity [GO:0004866]; lipid binding [GO:0008289]
d1tnul__d1h3ba2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1tnya__d4ydea___1	Metazoa		Chordata		CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]		negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]		CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]		CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	
d1tnyj__d1h35c2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1tnyj__d1n95b___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d1tnzb__d1h36b2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1tnzf__d1w6ja2__1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; membrane [GO:0016020]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; cholesterol biosynthetic process [GO:0006695]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of protein stability [GO:0031647]; steroid biosynthetic process [GO:0006694]; triterpenoid biosynthetic process [GO:0016104]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	cholesterol biosynthetic process [GO:0006695]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of protein stability [GO:0031647]; steroid biosynthetic process [GO:0006694]; triterpenoid biosynthetic process [GO:0016104]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; membrane [GO:0016020]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]
d1tnzh__d1h39a2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d1to4b1_d4rvpf___1	Metazoa	Viridiplantae	Platyhelminthes	Streptophyta	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1to7a2_d1pfqb2__1		Metazoa		Chordata		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1toab__d2ov3a___1			Spirochaetes	Cyanobacteria	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; zinc ion transport [GO:0006829]	metal ion binding [GO:0046872]; metal ion transport [GO:0030001]	cell adhesion [GO:0007155]; zinc ion transport [GO:0006829]	metal ion transport [GO:0030001]	periplasmic space [GO:0042597]		metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1tom.1_d3mu4a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1tooa__d4depd1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]	interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]
d1toq.3_d2bmzb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1toua__d5hwza___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	vasodilation [GO:0042311]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	extracellular region [GO:0005576]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d1tp0a__d1ry7a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1tp3a1_d4amha1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]; cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]	cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]
d1tp8.2_d3r50a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1tp8.4_d2hyrb1__1	Viridiplantae		Streptophyta	Rhodophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	cell [GO:0005623]; carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]				cell [GO:0005623]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]
d1tp8.4_d4pikc1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1tp9a1_d3a5wb___1	Viridiplantae		Streptophyta	Crenarchaeota	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1tp9d__d2mzca1__1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d1tp9d__d3vi7d1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1tpc2__d5bmwb___1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]		methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]
d1tpdb__d2yc8a___1					cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]; glycosome [GO:0020015]		triose-phosphate isomerase activity [GO:0004807]	
d1tpea__d1w0mg___1				Crenarchaeota	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytoplasm [GO:0005737]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1tppa__d1eaxa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1tpua__d1treb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]
d1tpva__d1suxa___1	Metazoa		Chordata		cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	glycosome [GO:0020015]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	triose-phosphate isomerase activity [GO:0004807]
d1tq0.1_d1rtl.2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1tq7.1_d4dvau___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	serine-type endopeptidase activity [GO:0004252]
d1tqbb1_d1wt5d___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1tqbb1_d5fyku___1	Metazoa		Chordata		anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1tqbb2_d1bqlh1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	lysozyme activity [GO:0003796]
d1tqbb2_d1p7qa1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1tqbc1_d3l7el2__1	Metazoa		Chordata		anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]		activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]		anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	
d1tqbc2_d2j8uf1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1tqcb2_d1bd2e2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1tqcc1_d1m7da1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1tqes__d3kova___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; histone methyltransferase complex [GO:0035097]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; histone deacetylase activity [GO:0004407]; histone deacetylase activity (H4-K16 specific) [GO:0034739]; histone deacetylase binding [GO:0042826]; protein deacetylase activity [GO:0033558]; protein kinase C binding [GO:0005080]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cellular response to insulin stimulus [GO:0032869]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; histone H4-K16 deacetylation [GO:1990678]; inflammatory response [GO:0006954]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of lipoprotein lipase activity [GO:0051005]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; regulation of skeletal muscle fiber development [GO:0048742]; regulation of striated muscle cell differentiation [GO:0051153]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cellular response to insulin stimulus [GO:0032869]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; histone H4-K16 deacetylation [GO:1990678]; inflammatory response [GO:0006954]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of lipoprotein lipase activity [GO:0051005]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; regulation of skeletal muscle fiber development [GO:0048742]; regulation of striated muscle cell differentiation [GO:0051153]	apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; histone methyltransferase complex [GO:0035097]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	histone deacetylase activity [GO:0004407]; histone deacetylase activity (H4-K16 specific) [GO:0034739]; histone deacetylase binding [GO:0042826]; protein deacetylase activity [GO:0033558]; protein kinase C binding [GO:0005080]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]	activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1tqwa2_d3vd9d5__1	Metazoa		Arthropoda	Proteobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	beta-galactosidase complex [GO:0009341]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1tqwa3_d3cv5a3__1	Metazoa	Metazoa	Arthropoda	Arthropoda	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1tqya1_d2buia2__1			Actinobacteria	Proteobacteria	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1tqyf2_d1cgka1__1		Viridiplantae	Actinobacteria	Streptophyta	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]			3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	naringenin-chalcone synthase activity [GO:0016210]
d1tqyg1_d2wktb2__1			Actinobacteria	Proteobacteria	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1tr0b__d5xzql___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta		lyase activity [GO:0016829]						lyase activity [GO:0016829]
d1tr0i__d3hx9a___1	Viridiplantae		Streptophyta	Actinobacteria		cell wall [GO:0005618]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; heme catabolic process [GO:0042167]		heme catabolic process [GO:0042167]		cell wall [GO:0005618]; plasma membrane [GO:0005886]		heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d1tr0j__d3hf5a1__1	Viridiplantae		Streptophyta	Proteobacteria		isomerase activity [GO:0016853]						isomerase activity [GO:0016853]
d1tr0l__d4nl5a___1	Viridiplantae		Streptophyta	Actinobacteria		cell wall [GO:0005618]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; heme catabolic process [GO:0042167]		heme catabolic process [GO:0042167]		cell wall [GO:0005618]; plasma membrane [GO:0005886]		heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d1tr0o__d3znjt___1	Viridiplantae		Streptophyta	Actinobacteria		muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]		beta-ketoadipate pathway [GO:0042952]				muconolactone delta-isomerase activity [GO:0016159]
d1tr0p__d1rjja___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta		chloroplast [GO:0009507]; cytosol [GO:0005829]; plastid [GO:0009536]; metal ion binding [GO:0046872]				chloroplast [GO:0009507]; cytosol [GO:0005829]; plastid [GO:0009536]		metal ion binding [GO:0046872]
d1tr1b__d1jz8c5__1			Firmicutes	Proteobacteria	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1trfa__d4cfrb___1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]	actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell leading edge [GO:0031252]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin-dependent ATPase activity [GO:0030898]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]; actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]		actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]		actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell leading edge [GO:0031252]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]	calcium ion binding [GO:0005509]	actin binding [GO:0003779]; actin-dependent ATPase activity [GO:0030898]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]
d1trha__d2qkya2__1	Fungi	Metazoa	Ascomycota	Chordata	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	triglyceride lipase activity [GO:0004806]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1trha__d5gv5a___1	Fungi	Fungi	Ascomycota	Basidiomycota	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]			triglyceride lipase activity [GO:0004806]	triglyceride lipase activity [GO:0004806]
d1trka2_d1itza2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	pentose-phosphate shunt [GO:0006098]	pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]
d1trka3_d5i5ea3__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1trkb2_d2ji9b2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	pentose-phosphate shunt [GO:0006098]	oxalate catabolic process [GO:0033611]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d1trma__d1p01a___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1trmb__d1anba___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]
d1trpa__d3whob___1	Fungi	Fungi	Ascomycota	Basidiomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]		endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1trqa__d1rgcb___1	Fungi	Fungi	Ascomycota	Ascomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1trra__d1wrss___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]
d1trsa__d3a2xj___1	Metazoa		Chordata	Crenarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytoplasm [GO:0005737]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1trva__d12gsa2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1trwa__d3rpnd___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]
d1ts0a__d4llob___1		Metazoa	Proteobacteria	Chordata	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	axolemma [GO:0030673]; axon [GO:0030424]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nuclear inner membrane [GO:0005637]; parallel fiber to Purkinje cell synapse [GO:0098688]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; potassium channel complex [GO:0034705]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; voltage-gated potassium channel complex [GO:0008076]; 14-3-3 protein binding [GO:0071889]; calmodulin binding [GO:0005516]; delayed rectifier potassium channel activity [GO:0005251]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; phosphatidylinositol bisphosphate binding [GO:1902936]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; voltage-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099508]; voltage-gated potassium channel activity [GO:0005249]; cellular response to calcium ion [GO:0071277]; ion transmembrane transport [GO:0034220]; phosphatidylinositol-mediated signaling [GO:0048015]; potassium ion transmembrane transport [GO:0071805]; regulation of cell population proliferation [GO:0042127]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; regulation of synaptic vesicle exocytosis [GO:2000300]; startle response [GO:0001964]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cellular response to calcium ion [GO:0071277]; ion transmembrane transport [GO:0034220]; phosphatidylinositol-mediated signaling [GO:0048015]; potassium ion transmembrane transport [GO:0071805]; regulation of cell population proliferation [GO:0042127]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; regulation of synaptic vesicle exocytosis [GO:2000300]; startle response [GO:0001964]		axolemma [GO:0030673]; axon [GO:0030424]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nuclear inner membrane [GO:0005637]; parallel fiber to Purkinje cell synapse [GO:0098688]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; potassium channel complex [GO:0034705]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; voltage-gated potassium channel complex [GO:0008076]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	14-3-3 protein binding [GO:0071889]; calmodulin binding [GO:0005516]; delayed rectifier potassium channel activity [GO:0005251]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; phosphatidylinositol bisphosphate binding [GO:1902936]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; voltage-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099508]; voltage-gated potassium channel activity [GO:0005249]
d1ts2a1_d1fnvc1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ts2a1_d1prtc1__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ts2b2_d2aq2b2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]	extracellular region [GO:0005576]	T cell receptor complex [GO:0042101]	toxin activity [GO:0090729]	
d1ts2c2_d1v1oa2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1ts3a1_d1qohe___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1ts3c2_d1eu4a2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ts4b1_d1eefg___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ts5a1_d2aq3b1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]	extracellular region [GO:0005576]	T cell receptor complex [GO:0042101]	toxin activity [GO:0090729]	
d1ts5a2_d1ts4b2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1ts6a__d2vv6c___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]		integral component of plasma membrane [GO:0005887]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d1ts7a__d4cqha1__1			Proteobacteria	Deinococcus-Thermus	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d1ts8a__d1s66l___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cyclic-guanylate-specific phosphodiesterase activity [GO:0071111]; heme binding [GO:0020037]; magnesium ion binding [GO:0000287]; oxygen sensor activity [GO:0019826]; response to oxygen levels [GO:0070482]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	response to oxygen levels [GO:0070482]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	cyclic-guanylate-specific phosphodiesterase activity [GO:0071111]; heme binding [GO:0020037]; magnesium ion binding [GO:0000287]; oxygen sensor activity [GO:0019826]
d1tsab__d2j56b___1				Proteobacteria		periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1tsac__d3dkhb1__1		Fungi		Ascomycota		extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		extraorganismal space [GO:0043245]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1tsbc__d2gbaa___1				Proteobacteria		periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1tsbd__d1aaja___1				Proteobacteria		periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1tsqa1_d4u8wb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1tsub1_d4y3wa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1tswa__d2tsrc___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; mRNA binding [GO:0003729]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; pyrimidine nucleobase metabolic process [GO:0006206]; regulation of translation [GO:0006417]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organic cyclic compound [GO:0014070]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; pyrimidine nucleobase metabolic process [GO:0006206]; regulation of translation [GO:0006417]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organic cyclic compound [GO:0014070]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]; uracil metabolic process [GO:0019860]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	thymidylate synthase activity [GO:0004799]	cofactor binding [GO:0048037]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; mRNA binding [GO:0003729]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d1ttaa__d2b14a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1ttca__d3do4d___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1ttcb__d1ttbb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1ttea2_d4m1nb1__1	Fungi		Ascomycota	Apicomplexa	cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; proteasome binding [GO:0070628]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; vesicle organization [GO:0016050]	nucleus [GO:0005634]; ATP binding [GO:0005524]; SUMO conjugating enzyme activity [GO:0061656]; protein sumoylation [GO:0016925]	ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; vesicle organization [GO:0016050]	protein sumoylation [GO:0016925]	cytosol [GO:0005829]; nucleus [GO:0005634]	nucleus [GO:0005634]	ATP binding [GO:0005524]; proteasome binding [GO:0070628]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; SUMO conjugating enzyme activity [GO:0061656]
d1ttfa__d5dfte___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]
d1ttha2_d2airg1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1ttha3_d2fzca1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1tthc2_d2otcb2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]
d1tthc3_d4jfrc2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1ttma__d1fsna___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1ttoc__d3d5ga___1	Fungi		Ascomycota	Actinobacteria	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]		endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1ttpb__d2zsja___1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	cytoplasm [GO:0005737]; pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]; threonine biosynthetic process [GO:0009088]	tryptophan biosynthetic process [GO:0000162]	threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]
d1tttb2_d4rd6a3__1			Deinococcus-Thermus	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1tttc2_d1jnya2__1			Deinococcus-Thermus	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1ttxa__d4yi8a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; calcium ion binding [GO:0005509]; phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]		phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]
d1tu0c2_d4oh7a2__1			Proteobacteria	Proteobacteria	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]; zinc ion binding [GO:0008270]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]		aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1tu7b1_d5ecne2__1	Metazoa	Viridiplantae	Nematoda (roundworms)	Streptophyta	glutathione transferase activity [GO:0004364]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]		glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]		apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	glutathione transferase activity [GO:0004364]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1tu7b2_d5kejb1__1	Metazoa	Viridiplantae	Nematoda (roundworms)	Streptophyta	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]					glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1tu8a1_d1v40d1__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	glutathione transferase activity [GO:0004364]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1tu8b1_d1md4b1__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1tu8b2_d3zmkb1__1	Metazoa	Metazoa	Nematoda (roundworms)	Arthropoda	glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]					glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d1tu8c2_d2fugk1__1	Metazoa		Nematoda (roundworms)	Deinococcus-Thermus	glutathione transferase activity [GO:0004364]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]				plasma membrane [GO:0005886]	glutathione transferase activity [GO:0004364]	quinone binding [GO:0048038]
d1tu8d2_d2vcwd2__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	glutathione transferase activity [GO:0004364]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1tu9a1_d3gqgd___1		Metazoa	Proteobacteria	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1tuee__d2jexa___1					host cell nucleus [GO:0042025]; host cytoskeleton [GO:0044163]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]; host cytoskeleton [GO:0044163]	host cell nucleus [GO:0042025]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]
d1tuia1_d1n0vc1__1		Fungi	Deinococcus-Thermus	Ascomycota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]
d1tuia1_d1q82d___1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]	cytoplasm [GO:0005737]	ribosome [GO:0005840]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1tuia2_d4rcza3__1			Deinococcus-Thermus	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1tuia3_d1n6ra___1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	actin cytoskeleton [GO:0015629]; anchored component of synaptic vesicle membrane [GO:0098993]; axon [GO:0030424]; axon terminus [GO:0043679]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic side of early endosome membrane [GO:0098559]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic early endosome [GO:0098842]; ruffle [GO:0001726]; somatodendritic compartment [GO:0036477]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; amyloid-beta clearance by transcytosis [GO:0150093]; blood coagulation [GO:0007596]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of exocytosis [GO:0045921]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286]; regulation of autophagosome assembly [GO:2000785]; regulation of endosome size [GO:0051036]; regulation of filopodium assembly [GO:0051489]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465]; viral RNA genome replication [GO:0039694]		amyloid-beta clearance by transcytosis [GO:0150093]; blood coagulation [GO:0007596]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of exocytosis [GO:0045921]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286]; regulation of autophagosome assembly [GO:2000785]; regulation of endosome size [GO:0051036]; regulation of filopodium assembly [GO:0051489]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465]; viral RNA genome replication [GO:0039694]	cytoplasm [GO:0005737]	actin cytoskeleton [GO:0015629]; anchored component of synaptic vesicle membrane [GO:0098993]; axon [GO:0030424]; axon terminus [GO:0043679]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic side of early endosome membrane [GO:0098559]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic early endosome [GO:0098842]; ruffle [GO:0001726]; somatodendritic compartment [GO:0036477]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1tuib2_d4m2la3__1			Deinococcus-Thermus	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1tuib3_d3a6pc___1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; melanosome [GO:0042470]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RISC complex [GO:0016442]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; nuclear export signal receptor activity [GO:0005049]; pre-miRNA binding [GO:0070883]; RISC complex binding [GO:1905172]; cell division [GO:0051301]; GTP metabolic process [GO:0046039]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of protein export from nucleus [GO:0046827]; pre-miRNA export from nucleus [GO:0035281]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]		cell division [GO:0051301]; GTP metabolic process [GO:0046039]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of protein export from nucleus [GO:0046827]; pre-miRNA export from nucleus [GO:0035281]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; melanosome [GO:0042470]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RISC complex [GO:0016442]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; nuclear export signal receptor activity [GO:0005049]; pre-miRNA binding [GO:0070883]; RISC complex binding [GO:1905172]
d1tuic1_d2hvyb1__1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; rRNA processing [GO:0006364]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]		rRNA processing [GO:0006364]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1tuic1_d3jb9b2__1		Fungi	Deinococcus-Thermus	Ascomycota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; post-mRNA release spliceosomal complex [GO:0071014]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387]		mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387]	cytoplasm [GO:0005737]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; post-mRNA release spliceosomal complex [GO:0071014]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1tuka__d2mala___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cell wall [GO:0005618]; extracellular region [GO:0005576]; lipid binding [GO:0008289]; cell wall organization [GO:0071555]; lipid transport [GO:0006869]	lipid binding [GO:0008289]; lipid transport [GO:0006869]	cell wall organization [GO:0071555]; lipid transport [GO:0006869]	lipid transport [GO:0006869]	cell wall [GO:0005618]; extracellular region [GO:0005576]		lipid binding [GO:0008289]	lipid binding [GO:0008289]
d1tupa__d3wtyf___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]
d1tupc__d1le9f2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1tuxa__d2c7fe2__1	Fungi		Ascomycota	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	xylan catabolic process [GO:0045493]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]		cytoplasm [GO:0005737]	endo-1,4-beta-xylanase activity [GO:0031176]	alpha-L-arabinofuranosidase activity [GO:0046556]
d1tuza__d1cb1a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; diacylglycerol kinase activity [GO:0004143]; kinase activity [GO:0016301]; NAD+ kinase activity [GO:0003951]; phospholipid binding [GO:0005543]; diacylglycerol metabolic process [GO:0046339]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; phosphatidic acid biosynthetic process [GO:0006654]; platelet activation [GO:0030168]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]	calcium ion binding [GO:0005509]; transition metal ion binding [GO:0046914]; vitamin D binding [GO:0005499]	diacylglycerol metabolic process [GO:0046339]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; phosphatidic acid biosynthetic process [GO:0006654]; platelet activation [GO:0030168]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]		cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; diacylglycerol kinase activity [GO:0004143]; kinase activity [GO:0016301]; NAD+ kinase activity [GO:0003951]; phospholipid binding [GO:0005543]	calcium ion binding [GO:0005509]; transition metal ion binding [GO:0046914]; vitamin D binding [GO:0005499]
d1tv6a1_d1j54a___1				Proteobacteria	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; DNA replication proofreading [GO:0045004]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA replication proofreading [GO:0045004]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]
d1tv9a3_d1kanb2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleotidyltransferase activity [GO:0016779]; response to antibiotic [GO:0046677]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]		damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	nucleotidyltransferase activity [GO:0016779]
d1tvaa1_d2bcva1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d1tvaa1_d4nm1a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d1tvaa3_d3k75e2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d1tvba1_d4m7jl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1tvbb2_d4xp9l1__1	Metazoa	Metazoa	Chordata	Arthropoda	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]; adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of plasma membrane [GO:0005887]; neuronal cell body membrane [GO:0032809]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]
d1tvbe2_d3eo1a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell development [GO:0048468]; cell-cell junction organization [GO:0045216]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; in utero embryonic development [GO:0001701]; inner ear development [GO:0048839]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell development [GO:0048468]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; inner ear development [GO:0048839]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]
d1tvdb__d2j1kg___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; innate immune response [GO:0045087]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; innate immune response [GO:0045087]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	extracellular space [GO:0005615]; T cell receptor complex [GO:0042101]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1tvdb__d5ksad2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; innate immune response [GO:0045087]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; innate immune response [GO:0045087]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular space [GO:0005615]; T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1tvea2_d1e5qh2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; homoserine dehydrogenase activity [GO:0004412]; NADP binding [GO:0050661]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		homoserine dehydrogenase activity [GO:0004412]; NADP binding [GO:0050661]	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]
d1tvhd2_d2d31a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1tvhd2_d4ozgd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1tvia__d4g0dc1__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; endoribonuclease activity [GO:0004521]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; rRNA processing [GO:0006364]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	rRNA processing [GO:0006364]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endoribonuclease activity [GO:0004521]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1tvja__d2fh2c3__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament depolymerization [GO:0030042]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1tvka2_d5h5ia2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1tvnb__d5okha___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; carbohydrate metabolic process [GO:0005975]; cell adhesion [GO:0007155]	6-phospho-beta-galactosidase activity [GO:0033920]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cell adhesion [GO:0007155]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	6-phospho-beta-galactosidase activity [GO:0033920]
d1tvpa__d5dt5g___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; carbohydrate metabolic process [GO:0005975]; cell adhesion [GO:0007155]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]; cell adhesion [GO:0007155]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1tvqa__d5kidc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]		antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	lipid binding [GO:0008289]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1tvra1_d1zblb___1				Firmicutes	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1tvya__d2aesa___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1tw1a__d1fr8a___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1tw1b__d3ee5a___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1tw2a2_d3ieie___1		Metazoa	Actinobacteria	Chordata	methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]; daunorubicin biosynthetic process [GO:1901771]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; C-terminal protein methylation [GO:0006481]; cellular protein modification process [GO:0006464]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	daunorubicin biosynthetic process [GO:1901771]	cellular protein modification process [GO:0006464]; C-terminal protein methylation [GO:0006481]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]	methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]	protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d1tw3a2_d5k0nd___1		Metazoa	Actinobacteria	Chordata	methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]; daunorubicin biosynthetic process [GO:1901771]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	daunorubicin biosynthetic process [GO:1901771]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d1tw3b1_d4omzd___1			Actinobacteria	Proteobacteria	methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]; daunorubicin biosynthetic process [GO:1901771]	DNA-binding transcription factor activity [GO:0003700]	daunorubicin biosynthetic process [GO:1901771]				methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]	DNA-binding transcription factor activity [GO:0003700]
d1tw3b2_d3tkya2__1		Viridiplantae	Actinobacteria	Streptophyta	methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]; daunorubicin biosynthetic process [GO:1901771]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]	daunorubicin biosynthetic process [GO:1901771]				methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]
d1tw4b__d2a2gc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]		aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	lipid binding [GO:0008289]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]
d1tw4b__d5hz9f1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]		cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	lipid binding [GO:0008289]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]
d1tw7a__d1xs7d___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d1tw7b__d4h3ja___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d1tw8a__d1yuva___1			Proteobacteria		DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]		DNA restriction-modification system [GO:0009307]				DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]	
d1tw8c__d1sa3a___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]
d1tw9a2_d3c73b___1	Metazoa		Nematoda (roundworms)	Firmicutes	transferase activity [GO:0016740]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]		cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]		cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	transferase activity [GO:0016740]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]
d1tw9b2_d4ofmd1__1	Metazoa	Metazoa	Nematoda (roundworms)	Nematoda (roundworms)	transferase activity [GO:0016740]	transferase activity [GO:0016740]					transferase activity [GO:0016740]	transferase activity [GO:0016740]
d1tw9c2_d4xcsb___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	transferase activity [GO:0016740]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; RNA binding [GO:0003723]; thioredoxin peroxidase activity [GO:0008379]; cell population proliferation [GO:0008283]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; erythrocyte homeostasis [GO:0034101]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of stress-activated MAPK cascade [GO:0032872]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]; retina homeostasis [GO:0001895]; skeletal system development [GO:0001501]		cell population proliferation [GO:0008283]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; erythrocyte homeostasis [GO:0034101]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of stress-activated MAPK cascade [GO:0032872]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]; retina homeostasis [GO:0001895]; skeletal system development [GO:0001501]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]	transferase activity [GO:0016740]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; RNA binding [GO:0003723]; thioredoxin peroxidase activity [GO:0008379]
d1tw9d2_d1k0cd2__1	Metazoa	Fungi	Nematoda (roundworms)	Ascomycota	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasm [GO:0005737]	transferase activity [GO:0016740]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]
d1tw9d2_d4weyb___1	Metazoa		Nematoda (roundworms)	Proteobacteria	transferase activity [GO:0016740]	cell [GO:0005623]; periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]; periplasmic space [GO:0042597]	transferase activity [GO:0016740]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]
d1tw9h2_d1jlvb2__1	Metazoa	Metazoa	Nematoda (roundworms)	Arthropoda	transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]					transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]
d1twbb__d1yfnc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ribosome [GO:0005840]; positive regulation of protein catabolic process [GO:0045732]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; ribosome [GO:0005840]; ATPase binding [GO:0051117]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; positive regulation of ATPase activity [GO:0032781]; positive regulation of protein catabolic process [GO:0045732]	positive regulation of protein catabolic process [GO:0045732]	positive regulation of ATPase activity [GO:0032781]; positive regulation of protein catabolic process [GO:0045732]	cytosol [GO:0005829]; ribosome [GO:0005840]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; ribosome [GO:0005840]		ATPase binding [GO:0051117]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d1twea__d3wo2a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d1twhc2_d1zyrb2__1	Fungi		Ascomycota	Deinococcus-Thermus	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]	transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]		DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d1twjd__d1vq3c1__1			Firmicutes	Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]
d1twma__d3wo3c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d1twna__d1oyka___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1twna__d2rd3d1__1	Metazoa		Chordata	Proteobacteria	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	thiaminase activity [GO:0050334]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]		enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	thiaminase activity [GO:0050334]
d1twsa__d1q7za1__1			Firmicutes	Thermotogae	dihydropteroate synthase activity [GO:0004156]; metal ion binding [GO:0046872]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methionine synthase activity [GO:0008705]; pteridine-containing compound metabolic process [GO:0042558]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	pteridine-containing compound metabolic process [GO:0042558]		cytosol [GO:0005829]	dihydropteroate synthase activity [GO:0004156]; metal ion binding [GO:0046872]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methionine synthase activity [GO:0008705]
d1tx6b__d1cbw.2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]	extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1tx6d__d1abi.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d1tx8a__d5dj7a___1	Metazoa		Chordata	Actinobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d1tx9a1_d1al02___1					host cell cytoplasm [GO:0030430]; viral procapsid maturation [GO:0046797]	host cell cytoplasm [GO:0030430]; viral procapsid maturation [GO:0046797]	viral procapsid maturation [GO:0046797]	viral procapsid maturation [GO:0046797]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]		
d1txgb2_d2uyyc1__1		Metazoa	Euryarchaeota	Chordata	glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerophospholipid metabolic process [GO:0006650]; phospholipid biosynthetic process [GO:0008654]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerophospholipid metabolic process [GO:0006650]; phospholipid biosynthetic process [GO:0008654]	positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]	glycerol-3-phosphate dehydrogenase complex [GO:0009331]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491]
d1txla__d4arha___1			Proteobacteria		cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]; cadmium ion binding [GO:0046870]; zinc ion binding [GO:0008270]; cellular response to zinc ion starvation [GO:0034224]; response to cadmium ion [GO:0046686]		cellular response to zinc ion starvation [GO:0034224]; response to cadmium ion [GO:0046686]		cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]		cadmium ion binding [GO:0046870]; zinc ion binding [GO:0008270]	
d1txtb2_d1teea2__1			Firmicutes	Actinobacteria	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	isoprenoid biosynthetic process [GO:0008299]	chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]			hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1txtc2_d2rjta2__1			Firmicutes	Firmicutes	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]			hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d1txvl3_d1c5db1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1txvl4_d1efqa___1		Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d1txxa__d1zzyb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1ty0a2_d3owep2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]	
d1ty0a2_d5tssa2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]	toxin activity [GO:0090729]
d1ty0b1_d1fd7d___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]	toxin activity [GO:0090729]
d1ty2a1_d1b1zc1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]	toxin activity [GO:0090729]
d1ty2a2_d3r8bc2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1ty2a2_d4rh6b2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]	
d1ty2b1_d1ktkd1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	pathogenesis [GO:0009405]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ty3l3_d1l7tl1__1		Metazoa		Chordata								
d1ty7l3_d3kpmb___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ty7l4_d2z9ta___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1tyfb__d3ib9b1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	acetyl-CoA carboxylase complex [GO:0009317]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]
d1tyff__d1xnwe1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	acetyl-CoA carboxylase complex [GO:0009317]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]
d1tyfl__d3trrd___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	isomerase activity [GO:0016853]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]		ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	isomerase activity [GO:0016853]
d1tyga__d4n6fb___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; sulfurtransferase activity [GO:0016783]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; transferase activity [GO:0016740]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	sulfurtransferase activity [GO:0016783]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d1tyja1_d1c7ta2__1			Firmicutes	Proteobacteria	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		periplasmic space [GO:0042597]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]
d1tyqb1_d1ma9b2__1	Metazoa	Metazoa	Chordata	Chordata	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin filament binding [GO:0051015]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d1tyqb1_d4foia2__1	Metazoa	Metazoa	Chordata	Chordata	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	actin filament binding [GO:0051015]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1tyqd1_d3dxkd2__1	Metazoa	Metazoa	Chordata	Chordata	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	actin filament binding [GO:0051015]	actin filament binding [GO:0051015]
d1tyta2_d1lqtb1__1				Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]; cell redox homeostasis [GO:0045454]	cell wall [GO:0005618]; ferredoxin-NAD+ reductase activity [GO:0008860]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP+ binding [GO:0070401]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]	oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell wall [GO:0005618]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]	ferredoxin-NAD+ reductase activity [GO:0008860]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP+ binding [GO:0070401]
d1tyzc__d2rkbe___1		Metazoa	Proteobacteria	Chordata	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; 1-aminocyclopropane-1-carboxylate metabolic process [GO:0018871]; amine catabolic process [GO:0009310]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; pyridoxal phosphate binding [GO:0030170]; L-serine catabolic process [GO:0006565]; L-threonine catabolic process to glycine [GO:0019518]; threonine catabolic process [GO:0006567]	1-aminocyclopropane-1-carboxylate metabolic process [GO:0018871]; amine catabolic process [GO:0009310]	L-serine catabolic process [GO:0006565]; L-threonine catabolic process to glycine [GO:0019518]; threonine catabolic process [GO:0006567]		cytosol [GO:0005829]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; pyridoxal phosphate binding [GO:0030170]
d1tz7a1_d3gxfd2__1		Metazoa	Aquificae	Chordata	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1tzbb__d3hjbc1__1			Crenarchaeota	Proteobacteria	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]; carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]		cytosol [GO:0005829]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]	glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d1tzca__d3nbub___1			Crenarchaeota	Proteobacteria	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]; carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; glucose-6-phosphate isomerase activity [GO:0004347]; identical protein binding [GO:0042802]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; cellular response to oxidative stress [GO:0034599]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	cellular response to oxidative stress [GO:0034599]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]		cytosol [GO:0005829]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]	glucose-6-phosphate isomerase activity [GO:0004347]; identical protein binding [GO:0042802]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d1tzgh1_d3v6fb1__1												
d1tzgh2_d1vcaa2__1		Metazoa		Chordata		alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]		acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell chemotaxis [GO:0060326]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]		alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]		cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]
d1tzgm1_d2xt1b1__1						viral process [GO:0016032]		viral process [GO:0016032]				
d1tzgm2_d3q5yc2__1												
d1tzha1_d2wubl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	proteolysis [GO:0006508]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1tzhb2_d1mrfl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	
d1tzhh1_d3q3gj2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]
d1tzhl1_d4yhyl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	
d1tzhl2_d4q6yd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1tzxb__d1sqfa1__1			Thermotogae	Proteobacteria	cytosol [GO:0005829]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]	cytosol [GO:0005829]; RNA binding [GO:0003723]; rRNA (cytosine-C5-)-methyltransferase activity [GO:0009383]; regulation of transcription, DNA-templated [GO:0006355]; rRNA base methylation [GO:0070475]	DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]	regulation of transcription, DNA-templated [GO:0006355]; rRNA base methylation [GO:0070475]	cytosol [GO:0005829]	cytosol [GO:0005829]	RNA binding [GO:0003723]	RNA binding [GO:0003723]; rRNA (cytosine-C5-)-methyltransferase activity [GO:0009383]
d1tzyf__d3av2e___1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleosome [GO:0000786]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1u0aa__d2z79b___1			Firmicutes	Firmicutes	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]			licheninase activity [GO:0042972]	endo-1,4-beta-xylanase activity [GO:0031176]
d1u0ab__d5hxvd___1		Fungi	Firmicutes	Ascomycota	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]			licheninase activity [GO:0042972]	endo-1,4-beta-xylanase activity [GO:0031176]
d1u0da__d3fd2a2__1	Viridiplantae	Viridiplantae	Chlorophyta	Chlorophyta	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	intron homing [GO:0006314]		chloroplast [GO:0009507]	chloroplast [GO:0009507]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d1u0ea1_d2cxnb___1	Metazoa	Metazoa	Chordata	Chordata	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d1u0fa1_d1vimc1__1	Metazoa		Chordata	Euryarchaeota	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate derivative binding [GO:0097367]; isomerase activity [GO:0016853]; carbohydrate derivative metabolic process [GO:1901135]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate derivative metabolic process [GO:1901135]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate derivative binding [GO:0097367]; isomerase activity [GO:0016853]
d1u0fb1_d1vimd1__1	Metazoa		Chordata	Euryarchaeota	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate derivative binding [GO:0097367]; isomerase activity [GO:0016853]; carbohydrate derivative metabolic process [GO:1901135]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate derivative metabolic process [GO:1901135]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate derivative binding [GO:0097367]; isomerase activity [GO:0016853]
d1u0gb1_d1jlhb___1	Metazoa	Metazoa	Chordata	Chordata	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d1u0ka2_d1u1xa1__1			Proteobacteria	Proteobacteria	catalytic activity [GO:0003824]; biosynthetic process [GO:0009058]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	biosynthetic process [GO:0009058]	pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]			catalytic activity [GO:0003824]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]
d1u0ka2_d4jcib___1			Proteobacteria	Proteobacteria	catalytic activity [GO:0003824]; biosynthetic process [GO:0009058]	4-hydroxyproline epimerase activity [GO:0047580]	biosynthetic process [GO:0009058]				catalytic activity [GO:0003824]	4-hydroxyproline epimerase activity [GO:0047580]
d1u0la1_d1eova1__1		Fungi	Thermotogae	Ascomycota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; rRNA binding [GO:0019843]; ribosomal small subunit biogenesis [GO:0042274]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	ribosomal small subunit biogenesis [GO:0042274]	aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; rRNA binding [GO:0019843]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]
d1u0ma1_d1m1oc1__1			Actinobacteria	Proteobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; melanin biosynthetic process [GO:0042438]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	melanin biosynthetic process [GO:0042438]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1u0mb1_d1xpkc1__1			Actinobacteria	Firmicutes	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; melanin biosynthetic process [GO:0042438]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	melanin biosynthetic process [GO:0042438]	isoprenoid biosynthetic process [GO:0008299]			transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d1u0nb__d3aluc___1	Metazoa	Metazoa	Chordata	Echinodermata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	metal ion binding [GO:0046872]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]		collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]		chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]	metal ion binding [GO:0046872]
d1u0nb__d4m17c1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1u0nd__d4c2bb___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d1u0oa__d2riac1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; hemostasis [GO:0007599]; liver development [GO:0001889]; placenta development [GO:0001890]; platelet activation [GO:0030168]; protein homooligomerization [GO:0051260]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; hemostasis [GO:0007599]; liver development [GO:0001889]; placenta development [GO:0001890]; platelet activation [GO:0030168]; protein homooligomerization [GO:0051260]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Weibel-Palade body [GO:0033093]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1u0qa__d4whtd1__1						viral envelope [GO:0019031]				viral envelope [GO:0019031]		
d1u0qb__d2fjfo1__1												
d1u0ub1_d1fj4a2__1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	pinosylvin synthase activity [GO:0050198]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1u0uc2_d1ulqb2__1	Viridiplantae		Streptophyta	Deinococcus-Thermus	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	biosynthetic process [GO:0009058]		cytoplasm [GO:0005737]		pinosylvin synthase activity [GO:0050198]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1u0ud1_d3v4xc1__1	Viridiplantae		Streptophyta	Firmicutes	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	biosynthetic process [GO:0009058]	isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]		pinosylvin synthase activity [GO:0050198]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d1u0uf2_d4wumb1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	naringenin-chalcone synthase activity [GO:0016210]; biosynthetic process [GO:0009058]	biosynthetic process [GO:0009058]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]		pinosylvin synthase activity [GO:0050198]	naringenin-chalcone synthase activity [GO:0016210]
d1u0va2_d1wdkc1__1	Viridiplantae		Streptophyta	Proteobacteria	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation multienzyme complex [GO:0036125]	naringenin-chalcone synthase activity [GO:0016210]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d1u0wa1_d4qavb2__1	Viridiplantae		Streptophyta	Proteobacteria	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]			naringenin-chalcone synthase activity [GO:0016210]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1u0wc1_d2rjtb1__1	Viridiplantae		Streptophyta	Firmicutes	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]			naringenin-chalcone synthase activity [GO:0016210]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d1u0wc1_d5bnsb2__1	Viridiplantae		Streptophyta	Proteobacteria	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		cytosol [GO:0005829]	naringenin-chalcone synthase activity [GO:0016210]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1u0wd1_d1wdld1__1	Viridiplantae		Streptophyta	Proteobacteria	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation multienzyme complex [GO:0036125]	naringenin-chalcone synthase activity [GO:0016210]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d1u0wd2_d1hzpb1__1	Viridiplantae		Streptophyta	Actinobacteria	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		cytoplasm [GO:0005737]	naringenin-chalcone synthase activity [GO:0016210]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d1u0xa__d2gtfx2__1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	vasodilation [GO:0042311]	vasodilation [GO:0042311]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]
d1u12b__d3mzhb1__1			Proteobacteria	Actinobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]		negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1u15a__d3r6qg___1	Metazoa		Chordata	Firmicutes	catalytic activity [GO:0003824]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process via ornithine [GO:0042450]	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]; aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	arginine biosynthetic process via ornithine [GO:0042450]	aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]			catalytic activity [GO:0003824]; structural constituent of eye lens [GO:0005212]	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]
d1u16a__d1fuqa___1	Metazoa		Chordata	Proteobacteria	catalytic activity [GO:0003824]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process via ornithine [GO:0042450]	tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	arginine biosynthetic process via ornithine [GO:0042450]	fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle enzyme complex [GO:0045239]	catalytic activity [GO:0003824]; structural constituent of eye lens [GO:0005212]	fumarate hydratase activity [GO:0004333]
d1u17b__d3cmpc___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	vasodilation [GO:0042311]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1u18b__d5h8ta1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; lipid homeostasis [GO:0055088]; retinoic acid biosynthetic process [GO:0002138]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	vasodilation [GO:0042311]	lipid homeostasis [GO:0055088]; retinoic acid biosynthetic process [GO:0002138]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]
d1u1ba__d1c9va___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1u1bb__d3ljea___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]		endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]
d1u1da2_d3qpbd___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	uridine phosphorylase activity [GO:0004850]
d1u1da2_d5miwb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]
d1u1ec__d4txld___1		Metazoa	Proteobacteria	Platyhelminthes	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	uridine phosphorylase activity [GO:0004850]
d1u1ed__d4dana___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	purine nucleoside metabolic process [GO:0042278]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	purine-nucleoside phosphorylase activity [GO:0004731]
d1u1fc__d3fb1c___1		Metazoa	Proteobacteria	Platyhelminthes	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	purine-nucleoside phosphorylase activity [GO:0004731]
d1u1gd__d4ttjb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]
d1u1ka1_d2dnma1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA binding [GO:0003723]; mRNA cis splicing, via spliceosome [GO:0045292]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	mRNA cis splicing, via spliceosome [GO:0045292]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	RNA binding [GO:0003723]
d1u1ka2_d3lpyb1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; U2-type catalytic step 2 spliceosome [GO:0071007]; cyclosporin A binding [GO:0016018]; mRNA binding [GO:0003729]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; mRNA splicing, via spliceosome [GO:0000398]; neutrophil degranulation [GO:0043312]; positive regulation of viral genome replication [GO:0045070]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	mRNA splicing, via spliceosome [GO:0000398]; neutrophil degranulation [GO:0043312]; positive regulation of viral genome replication [GO:0045070]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; U2-type catalytic step 2 spliceosome [GO:0071007]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	cyclosporin A binding [GO:0016018]; mRNA binding [GO:0003729]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]
d1u1ma2_d2kxfa1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cell junction [GO:0030054]; nucleoplasm [GO:0005654]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	cell junction [GO:0030054]; nucleoplasm [GO:0005654]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d1u1oa2_d5oo6e___1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]
d1u1pa1_d2vooa2__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear chromosome, telomeric region [GO:0000784]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049]; histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	cytoplasm [GO:0005737]; nuclear chromosome, telomeric region [GO:0000784]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049]
d1u1qa2_d2x1fa1__1	Metazoa	Fungi	Chordata	Ascomycota	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; mRNA binding [GO:0003729]; mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	mRNA binding [GO:0003729]
d1u1ra1_d4ckod4__1	Metazoa		Chordata		catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]		cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]		catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]		G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	
d1u1ra2_d3b4ma___1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear inclusion body [GO:0042405]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; cellular response to lipopolysaccharide [GO:0071222]; MAPK cascade [GO:0000165]; modification by virus of host mRNA processing [GO:0046778]; mRNA 3'-end processing [GO:0031124]; mRNA splicing, via spliceosome [GO:0000398]; muscle contraction [GO:0006936]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of polynucleotide adenylyltransferase activity [GO:1904247]; RNA processing [GO:0006396]; termination of RNA polymerase II transcription [GO:0006369]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cellular response to lipopolysaccharide [GO:0071222]; MAPK cascade [GO:0000165]; modification by virus of host mRNA processing [GO:0046778]; mRNA 3'-end processing [GO:0031124]; mRNA splicing, via spliceosome [GO:0000398]; muscle contraction [GO:0006936]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of polynucleotide adenylyltransferase activity [GO:1904247]; RNA processing [GO:0006396]; termination of RNA polymerase II transcription [GO:0006369]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	cytoplasm [GO:0005737]; nuclear inclusion body [GO:0042405]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]
d1u1sa1_d4mmkh___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]	cytosol [GO:0005829]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d1u1sc__d4f77o___1			Proteobacteria		cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]		pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]		cytosol [GO:0005829]		RNA binding [GO:0003723]	
d1u1wa1_d4ijzb1__1			Proteobacteria	Proteobacteria	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	lysine biosynthetic process via diaminopimelate [GO:0009089]		cytosol [GO:0005829]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]	diaminopimelate epimerase activity [GO:0008837]
d1u1wb2_d3ekmc2__1		Viridiplantae	Proteobacteria	Streptophyta	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	lysine biosynthetic process via diaminopimelate [GO:0009089]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]	diaminopimelate epimerase activity [GO:0008837]
d1u21b__d2qpfh___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1u26b1_d3moza___1			Firmicutes	Firmicutes	protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]					protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d1u27a1_d1oqnb___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; growth cone [GO:0030426]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; inositol 1,4,5 trisphosphate binding [GO:0070679]; lipid binding [GO:0008289]; negative regulation of dendrite development [GO:2000171]; regulation of ARF protein signal transduction [GO:0032012]; regulation of cell adhesion [GO:0030155]	apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; growth cone [GO:0030426]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; integral component of membrane [GO:0016021]; main axon [GO:0044304]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; terminal bouton [GO:0043195]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; growth factor receptor binding [GO:0070851]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; peptidase activator activity [GO:0016504]; PTB domain binding [GO:0051425]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron differentiation [GO:0045665]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein binding [GO:0032092]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein phosphorylation [GO:0006468]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of translation [GO:0006417]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	negative regulation of dendrite development [GO:2000171]; regulation of ARF protein signal transduction [GO:0032012]; regulation of cell adhesion [GO:0030155]	activation of MAPK activity [GO:0000187]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron differentiation [GO:0045665]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein binding [GO:0032092]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein phosphorylation [GO:0006468]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of translation [GO:0006417]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; growth cone [GO:0030426]; plasma membrane [GO:0005886]; ruffle [GO:0001726]	apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; growth cone [GO:0030426]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; integral component of membrane [GO:0016021]; main axon [GO:0044304]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; terminal bouton [GO:0043195]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; inositol 1,4,5 trisphosphate binding [GO:0070679]; lipid binding [GO:0008289]	DNA binding [GO:0003677]; enzyme binding [GO:0019899]; growth factor receptor binding [GO:0070851]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; peptidase activator activity [GO:0016504]; PTB domain binding [GO:0051425]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; transition metal ion binding [GO:0046914]
d1u2ea__d4a16a1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; 2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity [GO:0052823]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; 3-(3-hydroxy)phenylpropionate catabolic process [GO:0019622]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]; acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	3-(3-hydroxy)phenylpropionate catabolic process [GO:0019622]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	cytoplasm [GO:0005737]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]	2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity [GO:0052823]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]	acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]
d1u2ja__d1gx2b___1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]	extracellular region [GO:0005576]; vacuole [GO:0005773]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1u2jb__d1dsea___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytosol [GO:0005829]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1u2jc__d2rc0x___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytosol [GO:0005829]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1u2jd__d2ccda2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]
d1u2jg__d1fhfc___1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]	extracellular region [GO:0005576]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1u2jh__d2pcbc___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytosol [GO:0005829]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1u2ka__d4jpua___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	response to oxidative stress [GO:0006979]	cytosol [GO:0005829]	integral component of membrane [GO:0016021]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1u2qa__d1jl3a___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; host cell endosome [GO:0044174]; plasma membrane [GO:0005886]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]; arsenate reductase (thioredoxin) activity [GO:0030612]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]	negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein dephosphorylation [GO:0006470]	response to arsenic-containing substance [GO:0046685]	extracellular region [GO:0005576]; host cell endosome [GO:0044174]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	protein tyrosine phosphatase activity [GO:0004725]	arsenate reductase (thioredoxin) activity [GO:0030612]; protein tyrosine phosphatase activity [GO:0004725]
d1u2sa__d4nava___1			Cyanobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]; sucrose biosynthetic process [GO:0005986]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	sucrose biosynthetic process [GO:0005986]	lipopolysaccharide biosynthetic process [GO:0009103]			magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1u2ta__d3ewib___1		Metazoa	Cyanobacteria	Chordata	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]; sucrose biosynthetic process [GO:0005986]	nucleus [GO:0005634]; N-acylneuraminate cytidylyltransferase activity [GO:0008781]; CMP-N-acetylneuraminate biosynthetic process [GO:0006055]; N-acetylneuraminate metabolic process [GO:0006054]	sucrose biosynthetic process [GO:0005986]	CMP-N-acetylneuraminate biosynthetic process [GO:0006055]; N-acetylneuraminate metabolic process [GO:0006054]		nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]	N-acylneuraminate cytidylyltransferase activity [GO:0008781]
d1u2vd2_d2p9id1__1	Metazoa	Metazoa	Chordata	Chordata	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	actin filament binding [GO:0051015]	actin filament binding [GO:0051015]
d1u2ya1_d3edjb3__1	Metazoa		Chordata	Bacteroidetes	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d1u32a__d4i5lf___1	Metazoa	Metazoa	Chordata	Chordata	cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; protein-containing complex [GO:0032991]; PTW/PP1 phosphatase complex [GO:0072357]; lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]	lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]	GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]
d1u35b__d1kx4e___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; nucleosome assembly [GO:0006334]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleosome assembly [GO:0006334]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1u35c1_d4wnna___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; nucleosome assembly [GO:0006334]	nuclear nucleosome [GO:0000788]; replication fork protection complex [GO:0031298]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin assembly or disassembly [GO:0006333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334]; postreplication repair [GO:0006301]	nucleosome assembly [GO:0006334]	chromatin assembly or disassembly [GO:0006333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334]; postreplication repair [GO:0006301]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]	nuclear nucleosome [GO:0000788]; replication fork protection complex [GO:0031298]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1u35f__d1p3md___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; nucleosome assembly [GO:0006334]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleosome assembly [GO:0006334]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1u37a1_d4k76a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; amyloid-beta binding [GO:0001540]; axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; intracellular protein transport [GO:0006886]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	amyloid-beta binding [GO:0001540]	ion channel binding [GO:0044325]
d1u38a1_d3stji2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; amyloid-beta binding [GO:0001540]; axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; intracellular protein transport [GO:0006886]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]	amyloid-beta binding [GO:0001540]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]
d1u3aa__d1xccc___1			Proteobacteria	Apicomplexa	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	peroxiredoxin activity [GO:0051920]
d1u3ab__d1xw6c2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d1u3ad__d2eiqa___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1u3ae__d1sjia1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; Z disc [GO:0030018]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	calcium ion binding [GO:0005509]
d1u3ba1_d1n7ta1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; amyloid-beta binding [GO:0001540]; axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	basal plasma membrane [GO:0009925]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; hemidesmosome [GO:0030056]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ErbB-2 class receptor binding [GO:0005176]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]; basal protein localization [GO:0045175]; cell adhesion [GO:0007155]; cellular response to tumor necrosis factor [GO:0071356]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165]	axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; intracellular protein transport [GO:0006886]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	basal protein localization [GO:0045175]; cell adhesion [GO:0007155]; cellular response to tumor necrosis factor [GO:0071356]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	basal plasma membrane [GO:0009925]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; hemidesmosome [GO:0030056]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	amyloid-beta binding [GO:0001540]	ErbB-2 class receptor binding [GO:0005176]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]
d1u3ba1_d4e3ba___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; amyloid-beta binding [GO:0001540]; axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]; activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; intracellular protein transport [GO:0006886]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]	beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]
d1u3ba2_d1zoka1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; amyloid-beta binding [GO:0001540]; axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; intracellular protein transport [GO:0006886]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]	amyloid-beta binding [GO:0001540]	ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]
d1u3ca1_d1dnpb1__1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleus [GO:0005634]; PML body [GO:0016605]; ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; anthocyanin-containing compound metabolic process [GO:0046283]; auxin transport [GO:0060918]; blue light signaling pathway [GO:0009785]; circadian regulation of calcium ion oscillation [GO:0010617]; circadian rhythm [GO:0007623]; defense response [GO:0006952]; detection of light stimulus [GO:0009583]; flavin adenine dinucleotide metabolic process [GO:0072387]; negative regulation of lateral root development [GO:1901332]; oxidation-reduction process [GO:0055114]; photomorphogenesis [GO:0009640]; photoprotection [GO:0010117]; phototropism [GO:0009638]; plant organ development [GO:0099402]; positive regulation of anion channel activity [GO:1901529]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of shade avoidance [GO:1902448]; positive regulation of systemic acquired resistance [GO:1901672]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of leaf morphogenesis [GO:1901371]; regulation of meristem growth [GO:0010075]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of secondary cell wall biogenesis [GO:2000652]; regulation of unidimensional cell growth [GO:0051510]; response to absence of light [GO:0009646]; response to blue light [GO:0009637]; response to far red light [GO:0010218]; response to high light intensity [GO:0009644]; response to light stimulus [GO:0009416]; response to low fluence blue light stimulus by blue low-fluence system [GO:0010244]; response to magnetism [GO:0071000]; response to red light [GO:0010114]; response to strigolactone [GO:1902347]; response to water deprivation [GO:0009414]; singlet oxygen-mediated programmed cell death [GO:0010343]; stomatal movement [GO:0010118]	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	anthocyanin-containing compound metabolic process [GO:0046283]; auxin transport [GO:0060918]; blue light signaling pathway [GO:0009785]; circadian regulation of calcium ion oscillation [GO:0010617]; circadian rhythm [GO:0007623]; defense response [GO:0006952]; detection of light stimulus [GO:0009583]; flavin adenine dinucleotide metabolic process [GO:0072387]; negative regulation of lateral root development [GO:1901332]; oxidation-reduction process [GO:0055114]; photomorphogenesis [GO:0009640]; photoprotection [GO:0010117]; phototropism [GO:0009638]; plant organ development [GO:0099402]; positive regulation of anion channel activity [GO:1901529]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of shade avoidance [GO:1902448]; positive regulation of systemic acquired resistance [GO:1901672]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of leaf morphogenesis [GO:1901371]; regulation of meristem growth [GO:0010075]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of secondary cell wall biogenesis [GO:2000652]; regulation of unidimensional cell growth [GO:0051510]; response to absence of light [GO:0009646]; response to blue light [GO:0009637]; response to far red light [GO:0010218]; response to high light intensity [GO:0009644]; response to light stimulus [GO:0009416]; response to low fluence blue light stimulus by blue low-fluence system [GO:0010244]; response to magnetism [GO:0071000]; response to red light [GO:0010114]; response to strigolactone [GO:1902347]; response to water deprivation [GO:0009414]; singlet oxygen-mediated programmed cell death [GO:0010343]; stomatal movement [GO:0010118]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleus [GO:0005634]; PML body [GO:0016605]		ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]
d1u3ga__d5n01b___1			Tenericutes	Proteobacteria	cytoplasm [GO:0005737]; 5-formyltetrahydrofolate cyclo-ligase activity [GO:0030272]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]	CoA-transferase activity [GO:0008410]			cytoplasm [GO:0005737]		5-formyltetrahydrofolate cyclo-ligase activity [GO:0030272]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]	CoA-transferase activity [GO:0008410]
d1u3ha1_d2qted___1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	integral component of membrane [GO:0016021]	adaptive immune response [GO:0002250]		T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]		
d1u3hb1_d1bbjl1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1u3hb1_d4oiim2__1	Metazoa		Chordata		T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1u3hc1_d3sknd1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1u3hc2_d3wexc1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	adaptive immune response [GO:0002250]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]		
d1u3he__d3oskb___1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	T cell receptor complex [GO:0042101]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]		
d1u3he__d3qdge1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1u3hh1_d2r1xa1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]		T cell receptor complex [GO:0042101]			
d1u3hh2_d4pjec1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1u3ma1_d4yxka___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; basement membrane [GO:0005604]; cell [GO:0005623]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; signaling receptor activity [GO:0038023]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular calcium ion homeostasis [GO:0006874]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor biosynthetic process [GO:0010870]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; protein insertion into plasma membrane [GO:0098737]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to calcium ion [GO:0051592]; response to oxidative stress [GO:0006979]	anchored component of membrane [GO:0031225]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; protein homooligomerization [GO:0051260]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular calcium ion homeostasis [GO:0006874]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor biosynthetic process [GO:0010870]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; protein insertion into plasma membrane [GO:0098737]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to calcium ion [GO:0051592]; response to oxidative stress [GO:0006979]	protein homooligomerization [GO:0051260]	anchored component of membrane [GO:0031225]; basement membrane [GO:0005604]; cell [GO:0005623]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	anchored component of membrane [GO:0031225]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; signaling receptor activity [GO:0038023]; type 5 metabotropic glutamate receptor binding [GO:0031802]	copper ion binding [GO:0005507]
d1u3na__d4rvpd___1		Viridiplantae	Firmicutes	Streptophyta	plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; removal of superoxide radicals [GO:0019430]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	removal of superoxide radicals [GO:0019430]		plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1u3pa__d4c8eb___1			Proteobacteria	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d1u3ta2_d1p0cb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; alcohol metabolic process [GO:0006066]; drug metabolic process [GO:0017144]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; zinc ion binding [GO:0008270]	alcohol metabolic process [GO:0006066]; drug metabolic process [GO:0017144]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; zinc ion binding [GO:0008270]
d1u3ua2_d1n92a2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1u3wa2_d5x8hc___1	Metazoa		Chordata	Bacteroidetes	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	oxidoreductase activity [GO:0016491]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	oxidoreductase activity [GO:0016491]
d1u3wb2_d2b83d2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]
d1u3wb2_d3lqfc___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1u40a__d5iwxf___1			Proteobacteria	Firmicutes	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d1u4aa1_d5w8ub___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; enzyme binding [GO:0019899]; negative regulation of DNA binding [GO:0043392]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	negative regulation of DNA binding [GO:0043392]; protein sumoylation [GO:0016925]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	enzyme binding [GO:0019899]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1u4fa__d1leia1__1	Metazoa	Metazoa	Chordata	Chordata	dendrite [GO:0030425]; dendritic spine [GO:0043197]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; intrinsic component of membrane [GO:0031224]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cellular response to mechanical stimulus [GO:0071260]; magnesium ion transport [GO:0015693]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of skeletal muscle contraction via regulation of action potential [GO:0014861]; relaxation of cardiac muscle [GO:0055119]; relaxation of skeletal muscle [GO:0090076]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cellular response to mechanical stimulus [GO:0071260]; magnesium ion transport [GO:0015693]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of skeletal muscle contraction via regulation of action potential [GO:0014861]; relaxation of cardiac muscle [GO:0055119]; relaxation of skeletal muscle [GO:0090076]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	dendrite [GO:0030425]; dendritic spine [GO:0043197]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; intrinsic component of membrane [GO:0031224]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; voltage-gated potassium channel complex [GO:0008076]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1u4ga__d3u9wa2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; bacterial-type flagellum-dependent swarming motility [GO:0071978]; pathogenesis [GO:0009405]; protein secretion by the type II secretion system [GO:0015628]; protein transport by the Sec complex [GO:0043952]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	bacterial-type flagellum-dependent swarming motility [GO:0071978]; pathogenesis [GO:0009405]; protein secretion by the type II secretion system [GO:0015628]; protein transport by the Sec complex [GO:0043952]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1u4na__d1jjid___1			Firmicutes	Euryarchaeota	hydrolase activity [GO:0016787]	hydrolase activity [GO:0016787]					hydrolase activity [GO:0016787]	hydrolase activity [GO:0016787]
d1u4qa3_d1hcib1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; actin filament capping [GO:0051693]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; pseudopodium [GO:0031143]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]; actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin filament capping [GO:0051693]	actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; pseudopodium [GO:0031143]; Z disc [GO:0030018]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]
d1u4qb1_d1hcib4__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; actin filament capping [GO:0051693]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; pseudopodium [GO:0031143]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]; actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin filament capping [GO:0051693]	actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; pseudopodium [GO:0031143]; Z disc [GO:0030018]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]
d1u4qb2_d3f31a___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; actin filament capping [GO:0051693]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; specific granule lumen [GO:0035580]; spectrin [GO:0008091]; tertiary granule lumen [GO:1904724]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; structural constituent of cytoskeleton [GO:0005200]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]; neutrophil degranulation [GO:0043312]	actin filament capping [GO:0051693]	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]; neutrophil degranulation [GO:0043312]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; specific granule lumen [GO:0035580]; spectrin [GO:0008091]; tertiary granule lumen [GO:1904724]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; structural constituent of cytoskeleton [GO:0005200]
d1u4sa2_d1smkc2__1		Viridiplantae	Apicomplexa	Streptophyta	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		glyoxysome [GO:0009514]	L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]
d1u55b__d1wc8a___1		Metazoa	Firmicutes	Chordata	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	cis-Golgi network membrane [GO:0033106]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; TRAPP complex [GO:0030008]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]	signal transduction [GO:0007165]	endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]	integral component of membrane [GO:0016021]	cis-Golgi network membrane [GO:0033106]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; TRAPP complex [GO:0030008]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d1u5bb2_d5vrba3__1	Metazoa		Chordata	Proteobacteria	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]		mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]		3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1u5dd__d3dxda___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; microtubule plus-end [GO:0035371]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; ruffle [GO:0001726]; T cell receptor complex [GO:0042101]; microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; adaptive immune response [GO:0002250]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of integrin activation [GO:0033625]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; T cell receptor signaling pathway [GO:0050852]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	adaptive immune response [GO:0002250]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of integrin activation [GO:0033625]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; T cell receptor signaling pathway [GO:0050852]	activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid-beta clearance [GO:1900221]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; microtubule plus-end [GO:0035371]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; ruffle [GO:0001726]; T cell receptor complex [GO:0042101]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi lumen [GO:0005796]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]	microtubule plus-end binding [GO:0051010]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]
d1u5fa1_d2y8fa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; B cell activation [GO:0042113]; negative regulation of cell population proliferation [GO:0008285]	cytoplasm [GO:0005737]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; R-SMAD binding [GO:0070412]; Ran GTPase binding [GO:0008536]; positive regulation of GTPase activity [GO:0043547]; protein export from nucleus [GO:0006611]	B cell activation [GO:0042113]; negative regulation of cell population proliferation [GO:0008285]	positive regulation of GTPase activity [GO:0043547]; protein export from nucleus [GO:0006611]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		Ran GTPase binding [GO:0008536]; R-SMAD binding [GO:0070412]
d1u5fa1_d4kaxb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; B cell activation [GO:0042113]; negative regulation of cell population proliferation [GO:0008285]	cell cortex [GO:0005938]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; recycling endosome membrane [GO:0055038]; ruffle [GO:0001726]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein N-terminus binding [GO:0047485]; thioesterase binding [GO:0031996]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to nerve growth factor stimulus [GO:1990090]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; intracellular protein transport [GO:0006886]; liver development [GO:0001889]; maintenance of postsynaptic density structure [GO:0099562]; myeloid cell apoptotic process [GO:0033028]; negative regulation of dendrite development [GO:2000171]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of receptor-mediated endocytosis [GO:0048261]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of presynapse assembly [GO:1905606]; regulation of Rac protein signal transduction [GO:0035020]; ruffle assembly [GO:0097178]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192]	B cell activation [GO:0042113]; negative regulation of cell population proliferation [GO:0008285]	cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to nerve growth factor stimulus [GO:1990090]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; intracellular protein transport [GO:0006886]; liver development [GO:0001889]; maintenance of postsynaptic density structure [GO:0099562]; myeloid cell apoptotic process [GO:0033028]; negative regulation of dendrite development [GO:2000171]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of receptor-mediated endocytosis [GO:0048261]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of presynapse assembly [GO:1905606]; regulation of Rac protein signal transduction [GO:0035020]; ruffle assembly [GO:0097178]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cell cortex [GO:0005938]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; recycling endosome membrane [GO:0055038]; ruffle [GO:0001726]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein N-terminus binding [GO:0047485]; thioesterase binding [GO:0031996]
d1u5gb__d1u5da1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; B cell activation [GO:0042113]; negative regulation of cell population proliferation [GO:0008285]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; microtubule plus-end [GO:0035371]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; ruffle [GO:0001726]; T cell receptor complex [GO:0042101]; microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; adaptive immune response [GO:0002250]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of integrin activation [GO:0033625]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; T cell receptor signaling pathway [GO:0050852]	B cell activation [GO:0042113]; negative regulation of cell population proliferation [GO:0008285]	adaptive immune response [GO:0002250]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of integrin activation [GO:0033625]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; microtubule plus-end [GO:0035371]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; ruffle [GO:0001726]; T cell receptor complex [GO:0042101]		microtubule plus-end binding [GO:0051010]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]
d1u5gd__d2uvma___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; B cell activation [GO:0042113]; negative regulation of cell population proliferation [GO:0008285]	cell-cell junction [GO:0005911]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; vesicle [GO:0031982]; 14-3-3 protein binding [GO:0071889]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein phosphatase 2A binding [GO:0051721]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; activation of protein kinase B activity [GO:0032148]; activation-induced cell death of T cells [GO:0006924]; aging [GO:0007568]; anoikis [GO:0043276]; apoptotic mitochondrial changes [GO:0008637]; carbohydrate transport [GO:0008643]; cell differentiation [GO:0030154]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell population proliferation [GO:0008283]; cell projection organization [GO:0030030]; cellular protein modification process [GO:0006464]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidised low-density lipoprotein particle stimulus [GO:0140052]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; endocrine pancreas development [GO:0031018]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization to mitochondrion [GO:0072655]; excitatory postsynaptic potential [GO:0060079]; execution phase of apoptosis [GO:0097194]; G protein-coupled receptor signaling pathway [GO:0007186]; germ cell development [GO:0007281]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen cell differentiation involved in embryonic placenta development [GO:0060709]; hyaluronan metabolic process [GO:0030212]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; interleukin-18-mediated signaling pathway [GO:0035655]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; maintenance of protein location in mitochondrion [GO:0072656]; mammary gland epithelial cell differentiation [GO:0060644]; maternal placenta development [GO:0001893]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of lymphocyte migration [GO:2000402]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase activity by protein phosphorylation [GO:0100002]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of proteolysis [GO:0045861]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; NIK/NF-kappaB signaling [GO:0038061]; nitric oxide biosynthetic process [GO:0006809]; osteoblast differentiation [GO:0001649]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peripheral nervous system myelin maintenance [GO:0032287]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphorylation [GO:0016310]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of organ growth [GO:0046622]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of mRNA stability [GO:0043488]; regulation of myelination [GO:0031641]; regulation of neuron projection development [GO:0010975]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of translation [GO:0006417]; response to fluid shear stress [GO:0034405]; response to food [GO:0032094]; response to growth hormone [GO:0060416]; response to heat [GO:0009408]; response to insulin-like growth factor stimulus [GO:1990418]; response to oxidative stress [GO:0006979]; response to UV-A [GO:0070141]; signal transduction [GO:0007165]; spinal cord development [GO:0021510]; striated muscle cell differentiation [GO:0051146]; T cell costimulation [GO:0031295]; TOR signaling [GO:0031929]; translation [GO:0006412]	B cell activation [GO:0042113]; negative regulation of cell population proliferation [GO:0008285]	activation-induced cell death of T cells [GO:0006924]; activation of protein kinase B activity [GO:0032148]; aging [GO:0007568]; anoikis [GO:0043276]; apoptotic mitochondrial changes [GO:0008637]; carbohydrate transport [GO:0008643]; cell differentiation [GO:0030154]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell population proliferation [GO:0008283]; cell projection organization [GO:0030030]; cellular protein modification process [GO:0006464]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidised low-density lipoprotein particle stimulus [GO:0140052]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; endocrine pancreas development [GO:0031018]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization to mitochondrion [GO:0072655]; excitatory postsynaptic potential [GO:0060079]; execution phase of apoptosis [GO:0097194]; germ cell development [GO:0007281]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen cell differentiation involved in embryonic placenta development [GO:0060709]; G protein-coupled receptor signaling pathway [GO:0007186]; hyaluronan metabolic process [GO:0030212]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-18-mediated signaling pathway [GO:0035655]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; maintenance of protein location in mitochondrion [GO:0072656]; mammary gland epithelial cell differentiation [GO:0060644]; maternal placenta development [GO:0001893]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of lymphocyte migration [GO:2000402]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase activity by protein phosphorylation [GO:0100002]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of proteolysis [GO:0045861]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; NIK/NF-kappaB signaling [GO:0038061]; nitric oxide biosynthetic process [GO:0006809]; osteoblast differentiation [GO:0001649]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peripheral nervous system myelin maintenance [GO:0032287]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphorylation [GO:0016310]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of organ growth [GO:0046622]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of mRNA stability [GO:0043488]; regulation of myelination [GO:0031641]; regulation of neuron projection development [GO:0010975]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of translation [GO:0006417]; response to fluid shear stress [GO:0034405]; response to food [GO:0032094]; response to growth hormone [GO:0060416]; response to heat [GO:0009408]; response to insulin-like growth factor stimulus [GO:1990418]; response to oxidative stress [GO:0006979]; response to UV-A [GO:0070141]; signal transduction [GO:0007165]; spinal cord development [GO:0021510]; striated muscle cell differentiation [GO:0051146]; T cell costimulation [GO:0031295]; TOR signaling [GO:0031929]; translation [GO:0006412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cell-cell junction [GO:0005911]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; vesicle [GO:0031982]		14-3-3 protein binding [GO:0071889]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein phosphatase 2A binding [GO:0051721]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]
d1u5ib__d1mq1b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	proteolysis [GO:0006508]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1u5ob__d4r9kc1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	limonene-1,2-epoxide hydrolase activity [GO:0018744]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]		cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]		identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d1u5pa2_d1cunc2__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; actin filament capping [GO:0051693]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; actin filament capping [GO:0051693]	actin filament capping [GO:0051693]	actin filament capping [GO:0051693]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]	cell cortex [GO:0005938]; costamere [GO:0043034]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]
d1u5ta2_d1u5ta1__1	Fungi	Fungi	Ascomycota	Ascomycota	cell [GO:0005623]; ESCRT II complex [GO:0000814]; late endosome membrane [GO:0031902]; metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266]; ubiquitin binding [GO:0043130]; ATP export [GO:1904669]; carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [GO:0000433]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	cell [GO:0005623]; ESCRT II complex [GO:0000814]; late endosome membrane [GO:0031902]; metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266]; ubiquitin binding [GO:0043130]; ATP export [GO:1904669]; carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [GO:0000433]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	ATP export [GO:1904669]; carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [GO:0000433]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	ATP export [GO:1904669]; carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [GO:0000433]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	cell [GO:0005623]; ESCRT II complex [GO:0000814]; late endosome membrane [GO:0031902]	cell [GO:0005623]; ESCRT II complex [GO:0000814]; late endosome membrane [GO:0031902]	metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266]; ubiquitin binding [GO:0043130]	metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266]; ubiquitin binding [GO:0043130]
d1u5wh__d2mjpb___1			Proteobacteria	Euryarchaeota	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleotide binding [GO:0000166]; nucleotide metabolic process [GO:0009117]; response to antibiotic [GO:0046677]; thiamine metabolic process [GO:0006772]	dITP diphosphatase activity [GO:0035870]; ITP diphosphatase activity [GO:0036220]; metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; XTP diphosphatase activity [GO:0036222]; nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleotide metabolic process [GO:0009117]; response to antibiotic [GO:0046677]; thiamine metabolic process [GO:0006772]	nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]			metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleotide binding [GO:0000166]	dITP diphosphatase activity [GO:0035870]; ITP diphosphatase activity [GO:0036220]; metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; XTP diphosphatase activity [GO:0036222]
d1u5ya__d5h4cb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; tumor necrosis factor receptor binding [GO:0005164]; immunoglobulin mediated immune response [GO:0016064]; immunoglobulin production in mucosal tissue [GO:0002426]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of germinal center formation [GO:0002636]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of immune response [GO:0050776]	extracellular space [GO:0005615]; protein secretion [GO:0009306]	immunoglobulin mediated immune response [GO:0016064]; immunoglobulin production in mucosal tissue [GO:0002426]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of germinal center formation [GO:0002636]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of immune response [GO:0050776]	protein secretion [GO:0009306]	cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]	extracellular space [GO:0005615]	cytokine activity [GO:0005125]; tumor necrosis factor receptor binding [GO:0005164]	
d1u6ah1_d2gi7b1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; tetraspanin-enriched microdomain [GO:0097197]; collagen binding [GO:0005518]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; blood coagulation [GO:0007596]; enzyme linked receptor protein signaling pathway [GO:0007167]; leukocyte migration [GO:0050900]; platelet activation [GO:0030168]		blood coagulation [GO:0007596]; enzyme linked receptor protein signaling pathway [GO:0007167]; leukocyte migration [GO:0050900]; platelet activation [GO:0030168]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; tetraspanin-enriched microdomain [GO:0097197]		collagen binding [GO:0005518]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]
d1u6ah2_d5bvje1__1	Metazoa		Chordata									
d1u6al1_d3bdbc___1	Metazoa	Metazoa	Chordata	Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]		
d1u6al1_d5h35g2__1	Metazoa		Chordata	Crenarchaeota		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]				integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		
d1u6ba__d2leca___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]
d1u6dx__d4ifnx___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]; cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]; cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]	disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]	disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]
d1u6ea1_d4ubtb1__1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d1u6eb1_d1nl7a2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1u6eb2_d1u0vb2__1		Viridiplantae	Actinobacteria	Streptophyta	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	naringenin-chalcone synthase activity [GO:0016210]
d1u6mb1_d1s7na___1			Firmicutes	Proteobacteria	N-acetyltransferase activity [GO:0008080]	cytoplasm [GO:0005737]; N-acetyltransferase activity [GO:0008080]; peptide-serine-N-acetyltransferase activity [GO:1990189]; ribosomal-protein-alanine N-acetyltransferase activity [GO:0008999]; N-terminal peptidyl-serine acetylation [GO:0017198]		N-terminal peptidyl-serine acetylation [GO:0017198]		cytoplasm [GO:0005737]	N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]; peptide-serine-N-acetyltransferase activity [GO:1990189]; ribosomal-protein-alanine N-acetyltransferase activity [GO:0008999]
d1u6mc1_d1iica2__1		Fungi	Firmicutes	Ascomycota	N-acetyltransferase activity [GO:0008080]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; replicative cell aging [GO:0001302]		N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; replicative cell aging [GO:0001302]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	N-acetyltransferase activity [GO:0008080]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d1u6rb1_d3l2gj1__1	Metazoa		Chordata		extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]		phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]		extracellular space [GO:0005615]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	
d1u6rb2_d3b6ra2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]	cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	extracellular space [GO:0005615]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]
d1u6sb1_d2wgfh2__1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]
d1u6sb2_d3g0ya2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1u6ta1_d2a2pa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471]; adipose tissue development [GO:0060612]; corticosterone secretion [GO:0035934]; hormone metabolic process [GO:0042445]; multicellular organism growth [GO:0035264]; response to selenium ion [GO:0010269]		adipose tissue development [GO:0060612]; corticosterone secretion [GO:0035934]; hormone metabolic process [GO:0042445]; multicellular organism growth [GO:0035264]; response to selenium ion [GO:0010269]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471]	SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	
d1u6zb1_d1xoma___1		Metazoa	Proteobacteria	Chordata	plasma membrane [GO:0005886]; exopolyphosphatase activity [GO:0004309]; identical protein binding [GO:0042802]; phosphorus metabolic process [GO:0006793]; polyphosphate catabolic process [GO:0006798]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	phosphorus metabolic process [GO:0006793]; polyphosphate catabolic process [GO:0006798]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	exopolyphosphatase activity [GO:0004309]; identical protein binding [GO:0042802]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d1u70a__d1rb2a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d1u71a__d3nrrb1__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]
d1u74a__d5sx0b2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1u74c1_d4coxb1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d1u74d__d4aana1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1u75c1_d4xv7a___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1u79b__d5hw8d___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast [GO:0009507]; chloroplast thylakoid lumen [GO:0009543]; plastid [GO:0009536]; thylakoid lumen [GO:0031977]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cytoplasm [GO:0005737]; fungal biofilm matrix [GO:0062040]; drug binding [GO:0008144]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; cellular response to drug [GO:0035690]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]		cellular response to drug [GO:0035690]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	chloroplast [GO:0009507]; chloroplast thylakoid lumen [GO:0009543]; plastid [GO:0009536]; thylakoid lumen [GO:0031977]	cytoplasm [GO:0005737]; fungal biofilm matrix [GO:0062040]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	drug binding [GO:0008144]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1u7oa__d3e84c___1	Metazoa		Chordata	Bacteroidetes	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; fructosamine metabolic process [GO:0030389]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	fructosamine metabolic process [GO:0030389]	lipopolysaccharide biosynthetic process [GO:0009103]			acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d1u7pc__d2r8za___1	Metazoa		Chordata	Proteobacteria	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; fructosamine metabolic process [GO:0030389]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	fructosamine metabolic process [GO:0030389]	lipopolysaccharide biosynthetic process [GO:0009103]			acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1u7ta__d2aa3d1__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrial ribonuclease P complex [GO:0030678]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity [GO:0047015]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; cholate 7-alpha-dehydrogenase activity [GO:0008709]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; RNA binding [GO:0003723]; testosterone dehydrogenase [NAD(P)] activity [GO:0030283]; tRNA binding [GO:0000049]; branched-chain amino acid catabolic process [GO:0009083]; lipid metabolic process [GO:0006629]; mitochondrial tRNA 3'-end processing [GO:1990180]; mitochondrial tRNA 5'-end processing [GO:0097745]; mitochondrial tRNA methylation [GO:0070901]; mitochondrial tRNA processing [GO:0090646]; mitochondrion organization [GO:0007005]; protein homotetramerization [GO:0051289]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	branched-chain amino acid catabolic process [GO:0009083]; lipid metabolic process [GO:0006629]; mitochondrial tRNA 3'-end processing [GO:1990180]; mitochondrial tRNA 5'-end processing [GO:0097745]; mitochondrial tRNA methylation [GO:0070901]; mitochondrial tRNA processing [GO:0090646]; mitochondrion organization [GO:0007005]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrial ribonuclease P complex [GO:0030678]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity [GO:0047015]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; cholate 7-alpha-dehydrogenase activity [GO:0008709]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; RNA binding [GO:0003723]; testosterone dehydrogenase [NAD(P)] activity [GO:0030283]; tRNA binding [GO:0000049]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d1u7xb__d2zp1a1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	tyrosyl-tRNA aminoacylation [GO:0006437]	tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]
d1u81a__d3qbta___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell leading edge [GO:0031252]; COPI-coated vesicle [GO:0030137]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; late endosome [GO:0005770]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal membrane [GO:0005778]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; trans-Golgi network [GO:0005802]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; phospholipase D activator activity [GO:1990583]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; actin filament organization [GO:0007015]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular copper ion homeostasis [GO:0006878]; cellular response to virus [GO:0098586]; dendritic spine organization [GO:0097061]; Golgi to transport vesicle transport [GO:0055108]; interleukin-12-mediated signaling pathway [GO:0035722]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; lysosomal membrane organization [GO:0097212]; mitotic cleavage furrow ingression [GO:1990386]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of endocytosis [GO:0045807]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of late endosome to lysosome transport [GO:1902824]; positive regulation of protein secretion [GO:0050714]; positive regulation of sodium ion transmembrane transport [GO:1902307]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of defense response to virus by virus [GO:0050690]; regulation of phospholipid metabolic process [GO:1903725]; regulation of receptor internalization [GO:0002090]; synaptic vesicle budding [GO:0070142]; very-low-density lipoprotein particle assembly [GO:0034379]; vesicle-mediated transport [GO:0016192]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi stack [GO:0005795]; Golgi-associated vesicle [GO:0005798]; lysosome [GO:0005764]; membrane [GO:0016020]; nucleus [GO:0005634]; phagocytic vesicle membrane [GO:0030670]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; GTPase activator activity [GO:0005096]; inositol phosphate phosphatase activity [GO:0052745]; inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; Rac GTPase binding [GO:0048365]; cilium assembly [GO:0060271]; in utero embryonic development [GO:0001701]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; lipid metabolic process [GO:0006629]; membrane organization [GO:0061024]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	actin filament organization [GO:0007015]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular copper ion homeostasis [GO:0006878]; cellular response to virus [GO:0098586]; dendritic spine organization [GO:0097061]; Golgi to transport vesicle transport [GO:0055108]; interleukin-12-mediated signaling pathway [GO:0035722]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; lysosomal membrane organization [GO:0097212]; mitotic cleavage furrow ingression [GO:1990386]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of endocytosis [GO:0045807]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of late endosome to lysosome transport [GO:1902824]; positive regulation of protein secretion [GO:0050714]; positive regulation of sodium ion transmembrane transport [GO:1902307]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of defense response to virus by virus [GO:0050690]; regulation of phospholipid metabolic process [GO:1903725]; regulation of receptor internalization [GO:0002090]; synaptic vesicle budding [GO:0070142]; very-low-density lipoprotein particle assembly [GO:0034379]; vesicle-mediated transport [GO:0016192]	cilium assembly [GO:0060271]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; lipid metabolic process [GO:0006629]; membrane organization [GO:0061024]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	cell [GO:0005623]; cell leading edge [GO:0031252]; COPI-coated vesicle [GO:0030137]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; late endosome [GO:0005770]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal membrane [GO:0005778]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; trans-Golgi network [GO:0005802]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi-associated vesicle [GO:0005798]; Golgi stack [GO:0005795]; lysosome [GO:0005764]; membrane [GO:0016020]; nucleus [GO:0005634]; phagocytic vesicle membrane [GO:0030670]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; phospholipase D activator activity [GO:1990583]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	GTPase activator activity [GO:0005096]; inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol phosphate phosphatase activity [GO:0052745]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; Rac GTPase binding [GO:0048365]
d1u87a2_d3tjkb___1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]		4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]		cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	glutathione transferase activity [GO:0004364]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d1u88a1_d2vd0a1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	glutathione transferase activity [GO:0004364]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1u88b2_d1guma2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1u88b2_d3qpme___1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]	glutathione transferase activity [GO:0004364]	peroxiredoxin activity [GO:0051920]
d1u8cb2_d1yvpb2__1	Metazoa	Metazoa	Chordata	Chordata	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; cell [GO:0005623]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin alphav-beta5 complex [GO:0034684]; integrin alphav-beta6 complex [GO:0034685]; integrin alphav-beta8 complex [GO:0034686]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; microvillus membrane [GO:0031528]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; specific granule membrane [GO:0035579]; coreceptor activity [GO:0015026]; extracellular matrix binding [GO:0050840]; extracellular matrix protein binding [GO:1990430]; fibronectin binding [GO:0001968]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; opsonin binding [GO:0001846]; protease binding [GO:0002020]; protein kinase C binding [GO:0005080]; transforming growth factor beta binding [GO:0050431]; virus receptor activity [GO:0001618]; voltage-gated calcium channel activity [GO:0005245]; angiogenesis [GO:0001525]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; endodermal cell differentiation [GO:0035987]; entry of symbiont into host cell by promotion of host phagocytosis [GO:0052066]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; negative chemotaxis [GO:0050919]; negative regulation of entry of bacterium into host cell [GO:2000536]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; neutrophil degranulation [GO:0043312]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of phagocytosis [GO:0050764]; regulation of transforming growth factor beta activation [GO:1901388]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor-beta secretion [GO:0038044]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral entry into host cell [GO:0046718]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; misfolded RNA binding [GO:0034336]; cell projection organization [GO:0030030]	angiogenesis [GO:0001525]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; endodermal cell differentiation [GO:0035987]; entry of symbiont into host cell by promotion of host phagocytosis [GO:0052066]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; negative chemotaxis [GO:0050919]; negative regulation of entry of bacterium into host cell [GO:2000536]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; neutrophil degranulation [GO:0043312]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of phagocytosis [GO:0050764]; regulation of transforming growth factor beta activation [GO:1901388]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor-beta secretion [GO:0038044]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral entry into host cell [GO:0046718]	cell projection organization [GO:0030030]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; cell [GO:0005623]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin alphav-beta5 complex [GO:0034684]; integrin alphav-beta6 complex [GO:0034685]; integrin alphav-beta8 complex [GO:0034686]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; microvillus membrane [GO:0031528]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; specific granule membrane [GO:0035579]	cytoplasm [GO:0005737]	coreceptor activity [GO:0015026]; extracellular matrix binding [GO:0050840]; extracellular matrix protein binding [GO:1990430]; fibronectin binding [GO:0001968]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; opsonin binding [GO:0001846]; protease binding [GO:0002020]; protein kinase C binding [GO:0005080]; transforming growth factor beta binding [GO:0050431]; virus receptor activity [GO:0001618]; voltage-gated calcium channel activity [GO:0005245]	metal ion binding [GO:0046872]; misfolded RNA binding [GO:0034336]
d1u8fp2_d1q0qa3__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]		aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]
d1u8fr2_d5o0va2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]		antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]		aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]	
d1u8ha2_d4om1l1__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1u8ia1_d5ksbe1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1u8ja1_d2w9dl1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1u8ja2_d3sbwa___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of T cell apoptotic process [GO:0070234]		adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of T cell apoptotic process [GO:0070234]		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		
d1u8jb1_d3q5yb2__1												
d1u8la1_d4fqql2__1		Metazoa		Chordata								
d1u8ma1_d4yhnb2__1												
d1u8ma2_d1q9lb1__1												
d1u8oa2_d2hkhl1__1		Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		antigen binding [GO:0003823]
d1u8pa1_d1i3re1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]		integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]		
d1u8qb1_d3l9rb___1		Metazoa		Chordata		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]		
d1u8rg3_d2gcxa1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]	transition metal ion binding [GO:0046914]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	transition metal ion binding [GO:0046914]
d1u8ri1_d1c0wd1__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein dimerization activity [GO:0046983]; SH3 domain binding [GO:0017124]; transition metal ion binding [GO:0046914]; protein homooligomerization [GO:0051260]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]	protein homooligomerization [GO:0051260]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein dimerization activity [GO:0046983]; SH3 domain binding [GO:0017124]; transition metal ion binding [GO:0046914]
d1u8ua__d4oapb___1			Proteobacteria	Firmicutes	outer membrane-bounded periplasmic space [GO:0030288]; acyl-CoA hydrolase activity [GO:0047617]; arylesterase activity [GO:0004064]; identical protein binding [GO:0042802]; lysophospholipase activity [GO:0004622]; myristoyl-[acyl-carrier-protein] hydrolase activity [GO:0016295]; myristoyl-CoA hydrolase activity [GO:0102991]; oleoyl-[acyl-carrier-protein] hydrolase activity [GO:0004320]; palmitoyl-[acyl-carrier-protein] hydrolase activity [GO:0016296]; palmitoyl-CoA hydrolase activity [GO:0016290]; peptidase activity [GO:0008233]; phospholipase activity [GO:0004620]; lipid metabolic process [GO:0006629]	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; xylan catabolic process [GO:0045493]	lipid metabolic process [GO:0006629]	xylan catabolic process [GO:0045493]	outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]	acyl-CoA hydrolase activity [GO:0047617]; arylesterase activity [GO:0004064]; identical protein binding [GO:0042802]; lysophospholipase activity [GO:0004622]; myristoyl-[acyl-carrier-protein] hydrolase activity [GO:0016295]; myristoyl-CoA hydrolase activity [GO:0102991]; oleoyl-[acyl-carrier-protein] hydrolase activity [GO:0004320]; palmitoyl-[acyl-carrier-protein] hydrolase activity [GO:0016296]; palmitoyl-CoA hydrolase activity [GO:0016290]; peptidase activity [GO:0008233]; phospholipase activity [GO:0004620]	acetylxylan esterase activity [GO:0046555]
d1u8va1_d3fcjb2__1		Fungi	Firmicutes	Ascomycota	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybutanoyl-CoA dehydratase activity [GO:0043721]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; vinylacetyl-CoA delta-isomerase activity [GO:0050393]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]		nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]			4-hydroxybutanoyl-CoA dehydratase activity [GO:0043721]; 4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; vinylacetyl-CoA delta-isomerase activity [GO:0050393]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d1u8vd1_d1w07b1__1		Viridiplantae	Firmicutes	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybutanoyl-CoA dehydratase activity [GO:0043721]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; vinylacetyl-CoA delta-isomerase activity [GO:0050393]	cytosol [GO:0005829]; peroxisome [GO:0005777]; plasmodesma [GO:0009506]; acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; jasmonic acid biosynthetic process [GO:0009695]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676]; response to cadmium ion [GO:0046686]; response to fungus [GO:0009620]; response to wounding [GO:0009611]		fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; jasmonic acid biosynthetic process [GO:0009695]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676]; response to cadmium ion [GO:0046686]; response to fungus [GO:0009620]; response to wounding [GO:0009611]		cytosol [GO:0005829]; peroxisome [GO:0005777]; plasmodesma [GO:0009506]	4-hydroxybutanoyl-CoA dehydratase activity [GO:0043721]; 4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; vinylacetyl-CoA delta-isomerase activity [GO:0050393]	acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]
d1u8vd1_d2c12a1__1		Fungi	Firmicutes	Ascomycota	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybutanoyl-CoA dehydratase activity [GO:0043721]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; vinylacetyl-CoA delta-isomerase activity [GO:0050393]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]		nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]			4-hydroxybutanoyl-CoA dehydratase activity [GO:0043721]; 4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; vinylacetyl-CoA delta-isomerase activity [GO:0050393]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d1u8wa__d1xiqf___1	Viridiplantae		Streptophyta	Apicomplexa	nucleus [GO:0005634]; peroxisome [GO:0005777]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; peroxisome [GO:0005777]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]
d1u8wb__d1vyaa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	nucleus [GO:0005634]; peroxisome [GO:0005777]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; peroxisome [GO:0005777]	nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]
d1u8wb__d3fbeb1__1	Viridiplantae		Streptophyta		nucleus [GO:0005634]; peroxisome [GO:0005777]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cellular response to hydrogen peroxide [GO:0070301]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; peroxisome [GO:0005777]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1u91a2_d5ukol2__1												
d1u91a2_d5xkub1__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d1u91b1_d1cd1a1__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1u92a1_d4nqed1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1u92b1_d3w39d2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1u93a1_d4qnpf2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1u93a2_d4b7ia2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1u95a1_d1sjha1__1		Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1u95b1_d1ic1a2__1		Metazoa		Chordata		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]		acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]
d1u9aa__d4onla___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; transferase complex [GO:1990234]; ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; multicellular organism development [GO:0007275]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; viral process [GO:0016032]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; viral process [GO:0016032]	DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; transferase complex [GO:1990234]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]	ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]	ubiquitin conjugating enzyme activity [GO:0061631]
d1u9ba__d2uyza1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; transferase complex [GO:1990234]; ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; multicellular organism development [GO:0007275]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; viral process [GO:0016032]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; viral process [GO:0016032]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; transferase complex [GO:1990234]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d1u9ic1_d4a82c2__1			Cyanobacteria	Firmicutes	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]	circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]	ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]
d1u9id1_d2xoke2__1		Fungi	Cyanobacteria	Ascomycota	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1u9ka__d2hkhl1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]; acute inflammatory response [GO:0002526]; cell migration [GO:0016477]; chemokine metabolic process [GO:0050755]; cytokine metabolic process [GO:0042107]; cytokine secretion involved in immune response [GO:0002374]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	acute inflammatory response [GO:0002526]; cell migration [GO:0016477]; chemokine metabolic process [GO:0050755]; cytokine metabolic process [GO:0042107]; cytokine secretion involved in immune response [GO:0002374]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	integral component of membrane [GO:0016021]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]	antigen binding [GO:0003823]
d1u9kb__d1fl6b2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]; acute inflammatory response [GO:0002526]; cell migration [GO:0016477]; chemokine metabolic process [GO:0050755]; cytokine metabolic process [GO:0042107]; cytokine secretion involved in immune response [GO:0002374]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]		acute inflammatory response [GO:0002526]; cell migration [GO:0016477]; chemokine metabolic process [GO:0050755]; cytokine metabolic process [GO:0042107]; cytokine secretion involved in immune response [GO:0002374]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]		integral component of membrane [GO:0016021]		scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]	
d1u9mc__d3ks0b___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	oxidation-reduction process [GO:0055114]	lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]
d1u9md__d1iccb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	oxidation-reduction process [GO:0055114]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1u9mf__d1hkoa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1u9oa1_d1qvtd1__1			Actinobacteria	Firmicutes	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]		DNA binding [GO:0003677]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1u9va__d4dhje___1	Metazoa	Metazoa	Chordata	Chordata	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1u9xa__d2arya1__1	Metazoa	Metazoa	Chordata	Chordata	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; mammary gland involution [GO:0060056]; neutrophil degranulation [GO:0043312]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; receptor catabolic process [GO:0032801]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of NMDA receptor activity [GO:2000310]; self proteolysis [GO:0097264]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; mammary gland involution [GO:0060056]; neutrophil degranulation [GO:0043312]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; receptor catabolic process [GO:0032801]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of NMDA receptor activity [GO:2000310]; self proteolysis [GO:0097264]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d1u9yb1_d1ecjc1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]
d1u9yc1_d1l1ra___1			Euryarchaeota		cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	transferase activity, transferring glycosyl groups [GO:0016757]; nucleoside metabolic process [GO:0009116]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]		ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]	transferase activity, transferring glycosyl groups [GO:0016757]
d1u9zc1_d3h83b1__1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1u9zd1_d5knxb___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	cytosol [GO:0005829]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; adenine salvage [GO:0006168]; GMP salvage [GO:0032263]; guanine salvage [GO:0006178]; hypoxanthine metabolic process [GO:0046100]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	adenine salvage [GO:0006168]; GMP salvage [GO:0032263]; guanine salvage [GO:0006178]; hypoxanthine metabolic process [GO:0046100]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]	cytosol [GO:0005829]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]
d1ua4a__d3umoa___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; ADP-specific glucokinase activity [GO:0043843]; glucokinase activity [GO:0004340]; magnesium ion binding [GO:0000287]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; 6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphofructokinase activity [GO:0008443]; tagatose-6-phosphate kinase activity [GO:0009024]; cellular response to DNA damage stimulus [GO:0006974]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cellular response to DNA damage stimulus [GO:0006974]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ADP-specific glucokinase activity [GO:0043843]; glucokinase activity [GO:0004340]; magnesium ion binding [GO:0000287]	6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphofructokinase activity [GO:0008443]; tagatose-6-phosphate kinase activity [GO:0009024]
d1ua5a1_d2wrtc2__1	Metazoa	Metazoa	Platyhelminthes	Platyhelminthes	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]				cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d1ua5a2_d1eoga2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1ua6h1_d3h3pl___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1uaab1_d1nktb4__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3'-5' exonuclease activity [GO:0008408]; ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; single-stranded DNA binding [GO:0003697]; bacterial-type DNA replication [GO:0044787]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; recombinational repair [GO:0000725]; response to radiation [GO:0009314]	cell envelope Sec protein transport complex [GO:0031522]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled protein transmembrane transporter activity [GO:0015462]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; intracellular protein transmembrane transport [GO:0065002]; protein import [GO:0017038]; protein targeting [GO:0006605]; protein transport by the Sec complex [GO:0043952]	bacterial-type DNA replication [GO:0044787]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; recombinational repair [GO:0000725]; response to radiation [GO:0009314]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; intracellular protein transmembrane transport [GO:0065002]; protein import [GO:0017038]; protein targeting [GO:0006605]; protein transport by the Sec complex [GO:0043952]	cytosol [GO:0005829]	cell envelope Sec protein transport complex [GO:0031522]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	3'-5' exonuclease activity [GO:0008408]; ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; single-stranded DNA binding [GO:0003697]	ATPase activity [GO:0016887]; ATPase-coupled protein transmembrane transporter activity [GO:0015462]; ATP binding [GO:0005524]
d1uacl__d3h9zd2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1uacy__d2dqjy___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1uadb__d2w83b___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cleavage furrow [GO:0032154]; cytoplasmic vesicle membrane [GO:0030659]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ATPase binding [GO:0051117]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; ubiquitin protein ligase binding [GO:0031625]; actin cytoskeleton reorganization [GO:0031532]; cell cycle [GO:0007049]; cell division [GO:0051301]; chemotaxis [GO:0006935]; exocytosis [GO:0006887]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane organization [GO:0061024]; membrane raft localization [GO:0051665]; neural tube closure [GO:0001843]; positive regulation of filopodium assembly [GO:0051491]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; recycling endosome membrane [GO:0055038]; ruffle [GO:0001726]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein N-terminus binding [GO:0047485]; thioesterase binding [GO:0031996]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to nerve growth factor stimulus [GO:1990090]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; intracellular protein transport [GO:0006886]; liver development [GO:0001889]; maintenance of postsynaptic density structure [GO:0099562]; myeloid cell apoptotic process [GO:0033028]; negative regulation of dendrite development [GO:2000171]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of receptor-mediated endocytosis [GO:0048261]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of presynapse assembly [GO:1905606]; regulation of Rac protein signal transduction [GO:0035020]; ruffle assembly [GO:0097178]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192]	actin cytoskeleton reorganization [GO:0031532]; cell cycle [GO:0007049]; cell division [GO:0051301]; chemotaxis [GO:0006935]; exocytosis [GO:0006887]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane organization [GO:0061024]; membrane raft localization [GO:0051665]; neural tube closure [GO:0001843]; positive regulation of filopodium assembly [GO:0051491]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; signal transduction [GO:0007165]	cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to nerve growth factor stimulus [GO:1990090]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; intracellular protein transport [GO:0006886]; liver development [GO:0001889]; maintenance of postsynaptic density structure [GO:0099562]; myeloid cell apoptotic process [GO:0033028]; negative regulation of dendrite development [GO:2000171]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of receptor-mediated endocytosis [GO:0048261]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of presynapse assembly [GO:1905606]; regulation of Rac protein signal transduction [GO:0035020]; ruffle assembly [GO:0097178]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192]	cell surface [GO:0009986]; cleavage furrow [GO:0032154]; cytoplasmic vesicle membrane [GO:0030659]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]	cell cortex [GO:0005938]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; recycling endosome membrane [GO:0055038]; ruffle [GO:0001726]	ATPase binding [GO:0051117]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; ubiquitin protein ligase binding [GO:0031625]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein N-terminus binding [GO:0047485]; thioesterase binding [GO:0031996]
d1uaga1_d5vvwa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]	ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]
d1uapa1_d2a73b8__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; collagen binding [GO:0005518]; heparin binding [GO:0008201]; peptidase activator activity [GO:0016504]; cellular response to leukemia inhibitory factor [GO:1990830]; multicellular organism development [GO:0007275]; proteolysis [GO:0006508]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	cellular response to leukemia inhibitory factor [GO:1990830]; multicellular organism development [GO:0007275]; proteolysis [GO:0006508]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	collagen binding [GO:0005518]; heparin binding [GO:0008201]; peptidase activator activity [GO:0016504]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d1uapa1_d2e2dc2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; collagen binding [GO:0005518]; heparin binding [GO:0008201]; peptidase activator activity [GO:0016504]; cellular response to leukemia inhibitory factor [GO:1990830]; multicellular organism development [GO:0007275]; proteolysis [GO:0006508]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular response to leukemia inhibitory factor [GO:1990830]; multicellular organism development [GO:0007275]; proteolysis [GO:0006508]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen binding [GO:0005518]; heparin binding [GO:0008201]; peptidase activator activity [GO:0016504]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1uaqa__d4ld4a___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]		cytoplasm [GO:0005737]; nucleus [GO:0005634]		5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]
d1uaqb__d1zczb2__1	Fungi		Ascomycota	Thermotogae	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; 'de novo' IMP biosynthetic process [GO:0006189]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]
d1uata__d3t6wb2__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]			periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1uaxa__d5c24a2__1			Euryarchaeota		cytoplasm [GO:0005737]; manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; RNA catabolic process [GO:0006401]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	RNA catabolic process [GO:0006401]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1uaya__d2uyya1__1		Metazoa	Deinococcus-Thermus	Chordata	oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]		positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]		cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	oxidoreductase activity [GO:0016491]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491]
d1ub5a2_d5a16b2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ub5h2_d3fo9h2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ub5l2_d4gxvl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ub6a1_d2ez0f2__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1ub6a2_d5gksd1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ub6b1_d2nxzb2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1ub6b2_d1eeye___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ub6b2_d4nqch1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ub6h1_d1a7rl___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ub6l1_d4apqb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ub6l2_d1eapb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ub7a2_d1xpmb2__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]	isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d1ub7c2_d2gfva2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1ub7d2_d1oxhd2__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d1ubga1_d2wwga___1			Actinobacteria	Apicomplexa	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA-dependent ATPase activity [GO:0008094]; single-stranded DNA binding [GO:0003697]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA-dependent ATPase activity [GO:0008094]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]
d1ubsb__d3vc3a___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]; cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	tryptophan biosynthetic process [GO:0000162]	cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]
d1ubva__d4rnqa2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d1ubwa__d5impb___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]		cytoplasm [GO:0005737]		dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]
d1ubza__d2b6wa___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ubza__d2i26l___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1uc3a__d2uumu___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1uc3d__d4ni1a___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1uc3d__d5nb3b___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1uc3i__d2uumi___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1uc3i__d4f4oe___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1uc3j__d3pt8b___1	Metazoa	Metazoa	Chordata	Mollusca	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1uc3l__d1a3od___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1uc4a__d6reqa1__1			Proteobacteria	Actinobacteria	propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]					propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d1uc5a__d3reqb1__1			Proteobacteria	Actinobacteria	propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]					propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d1uc7a__d2o87a___1			Proteobacteria	Firmicutes	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell [GO:0005623]	electron transfer activity [GO:0009055]; protein-disulfide reductase activity [GO:0047134]	protein disulfide oxidoreductase activity [GO:0015035]
d1uc8a1_d3etjb2__1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	'de novo' IMP biosynthetic process [GO:0006189]		cytosol [GO:0005829]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]
d1uc8b1_d5m7ef1__1		Metazoa	Deinococcus-Thermus	Chordata	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]		cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1ucaa__d1ucga___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]					lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]
d1ucaa__d3tbja___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]					lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]
d1ucbh1_d1qtyu___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]
d1ucbh2_d5d7ic2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ucbl1_d1rpqb2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	Fc-epsilon receptor signaling pathway [GO:0038095]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	IgE binding [GO:0019863]
d1ucbl2_d2clra1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ucca__d1j1ga1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]					lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	lyase activity [GO:0016829]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]
d1ucja__d4haad___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1uckb__d1brjc___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1ucnc__d4dz6f1__1	Metazoa		Chordata	Spirochaetes	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]; cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]	cytosol [GO:0005829]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1ucoa__d3c8qa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1ucpa__d3ezqo1__1	Metazoa	Metazoa	Chordata	Chordata	AIM2 inflammasome complex [GO:0097169]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; IkappaB kinase complex [GO:0008385]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; NLRP1 inflammasome complex [GO:0072558]; NLRP3 inflammasome complex [GO:0072559]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; BMP receptor binding [GO:0070700]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; interleukin-6 receptor binding [GO:0005138]; ion channel binding [GO:0044325]; myosin I binding [GO:0017024]; protease binding [GO:0002020]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; Pyrin domain binding [GO:0032090]; tropomyosin binding [GO:0005523]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; defense response to Gram-negative bacterium [GO:0050829]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta production [GO:0032611]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; macropinocytosis [GO:0044351]; myeloid dendritic cell activation [GO:0001773]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; neutrophil degranulation [GO:0043312]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of antigen processing and presentation of peptide antigen via MHC class II [GO:0002588]; positive regulation of apoptotic process [GO:0043065]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phagocytosis [GO:0050766]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell migration [GO:2000406]; positive regulation of tumor necrosis factor production [GO:0032760]; protein homooligomerization [GO:0051260]; regulation of autophagy [GO:0010506]; regulation of GTPase activity [GO:0043087]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]; regulation of protein stability [GO:0031647]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; defense response to Gram-negative bacterium [GO:0050829]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta production [GO:0032611]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; macropinocytosis [GO:0044351]; myeloid dendritic cell activation [GO:0001773]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; neutrophil degranulation [GO:0043312]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of antigen processing and presentation of peptide antigen via MHC class II [GO:0002588]; positive regulation of apoptotic process [GO:0043065]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phagocytosis [GO:0050766]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell migration [GO:2000406]; positive regulation of tumor necrosis factor production [GO:0032760]; protein homooligomerization [GO:0051260]; regulation of autophagy [GO:0010506]; regulation of GTPase activity [GO:0043087]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]; regulation of protein stability [GO:0031647]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	AIM2 inflammasome complex [GO:0097169]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; IkappaB kinase complex [GO:0008385]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; NLRP1 inflammasome complex [GO:0072558]; NLRP3 inflammasome complex [GO:0072559]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	BMP receptor binding [GO:0070700]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; interleukin-6 receptor binding [GO:0005138]; ion channel binding [GO:0044325]; myosin I binding [GO:0017024]; protease binding [GO:0002020]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; Pyrin domain binding [GO:0032090]; tropomyosin binding [GO:0005523]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]
d1ucy.1_d2qc2b___1	Metazoa		Chordata		extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1ud1a2_d2bnna2__1	Viridiplantae		Streptophyta	Actinobacteria	endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]		nutrient reservoir activity [GO:0045735]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d1ud1c2_d3zdsl___1	Viridiplantae		Streptophyta	Proteobacteria	endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]		L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]	protein-DNA complex [GO:0032993]	nutrient reservoir activity [GO:0045735]	DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1ud2a2_d5fcza2__1			Firmicutes	Actinobacteria	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-N-acetylhexosaminidase activity [GO:0004563]
d1ud3a1_d1ot2a3__1			Firmicutes	Firmicutes	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1ud3a2_d2gvya2__1		Fungi	Firmicutes	Ascomycota	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]		cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1ud4a2_d1hx0a2__1		Metazoa	Firmicutes	Chordata	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]		extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1ud5a2_d3pzta___1			Firmicutes	Firmicutes	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]			calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d1ud6a1_d1ehaa2__1			Firmicutes	Crenarchaeota	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]		cytoplasm [GO:0005737]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]
d1ud6a2_d3mmud___1			Firmicutes	Thermotogae	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]		extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1ud9a1_d6ap4l1__1			Crenarchaeota	Proteobacteria	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]		cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1ud9b1_d2ntih1__1			Crenarchaeota	Crenarchaeota	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]		PCNA complex [GO:0043626]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d1ud9d1_d6amsc3__1			Crenarchaeota	Proteobacteria	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA strand elongation involved in DNA replication [GO:0006271]		cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1ud9d2_d3k4xa5__1		Fungi	Crenarchaeota	Ascomycota	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]		nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d1udda__d1xjzb___1		Metazoa	Euryarchaeota	Chordata	thiaminase activity [GO:0050334]; thiamine metabolic process [GO:0006772]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	thiamine metabolic process [GO:0006772]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]		caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	thiaminase activity [GO:0050334]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1uddc__d1yafa___1			Euryarchaeota	Firmicutes	thiaminase activity [GO:0050334]; thiamine metabolic process [GO:0006772]	cytosol [GO:0005829]; thiaminase activity [GO:0050334]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	thiamine metabolic process [GO:0006772]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]		cytosol [GO:0005829]	thiaminase activity [GO:0050334]	thiaminase activity [GO:0050334]
d1uddc__d2qppa___1		Metazoa	Euryarchaeota	Chordata	thiaminase activity [GO:0050334]; thiamine metabolic process [GO:0006772]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	thiamine metabolic process [GO:0006772]	cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	thiaminase activity [GO:0050334]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d1udga__d4lylk1__1					host cell nucleus [GO:0042025]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]		base-excision repair [GO:0006284]		host cell nucleus [GO:0042025]		uracil DNA N-glycosylase activity [GO:0004844]	
d1udma1_d1m4jb___1	Metazoa	Metazoa	Chordata	Chordata	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]; defense response to fungus [GO:0050832]; regulation of actin filament polymerization [GO:0030833]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; filopodium [GO:0030175]; myofibril [GO:0030016]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; actin filament depolymerization [GO:0030042]; barbed-end actin filament capping [GO:0051016]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of neuron projection development [GO:0010976]; regulation of actin phosphorylation [GO:0043538]; regulation of lamellipodium assembly [GO:0010591]; sequestering of actin monomers [GO:0042989]	defense response to fungus [GO:0050832]; regulation of actin filament polymerization [GO:0030833]	actin filament depolymerization [GO:0030042]; barbed-end actin filament capping [GO:0051016]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of neuron projection development [GO:0010976]; regulation of actin phosphorylation [GO:0043538]; regulation of lamellipodium assembly [GO:0010591]; sequestering of actin monomers [GO:0042989]	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; filopodium [GO:0030175]; myofibril [GO:0030016]; perinuclear region of cytoplasm [GO:0048471]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]
d1udna2_d3b4te2__1			Aquificae	Actinobacteria	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	plasma membrane [GO:0005886]; 3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]		plasma membrane [GO:0005886]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d1udoa2_d3l7za2__1			Aquificae	Crenarchaeota	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d1udqa1_d1i96e1__1			Aquificae	Deinococcus-Thermus	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	translation [GO:0006412]		ribosome [GO:0005840]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1udqa2_d2po1a2__1			Aquificae	Euryarchaeota	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	RNA catabolic process [GO:0006401]		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	3'-5'-exoribonuclease activity [GO:0000175]
d1udra__d3jtea1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	catalytic activity [GO:0003824]; phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	catalytic activity [GO:0003824]
d1udrc__d1ordb1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; ornithine decarboxylase activity [GO:0004586]; cellular amino acid metabolic process [GO:0006520]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	ornithine decarboxylase activity [GO:0004586]
d1udsa2_d2br2k2__1			Aquificae	Crenarchaeota	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	3'-5'-exoribonuclease activity [GO:0000175]
d1udxa2_d1tu3e___1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; ribosome biogenesis [GO:0042254]	actin cytoskeleton [GO:0015629]; anchored component of synaptic vesicle membrane [GO:0098993]; axon [GO:0030424]; axon terminus [GO:0043679]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic side of early endosome membrane [GO:0098559]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic early endosome [GO:0098842]; ruffle [GO:0001726]; somatodendritic compartment [GO:0036477]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; amyloid-beta clearance by transcytosis [GO:0150093]; blood coagulation [GO:0007596]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of exocytosis [GO:0045921]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286]; regulation of autophagosome assembly [GO:2000785]; regulation of endosome size [GO:0051036]; regulation of filopodium assembly [GO:0051489]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465]; viral RNA genome replication [GO:0039694]	ribosome biogenesis [GO:0042254]	amyloid-beta clearance by transcytosis [GO:0150093]; blood coagulation [GO:0007596]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of exocytosis [GO:0045921]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286]; regulation of autophagosome assembly [GO:2000785]; regulation of endosome size [GO:0051036]; regulation of filopodium assembly [GO:0051489]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465]; viral RNA genome replication [GO:0039694]	cytoplasm [GO:0005737]	actin cytoskeleton [GO:0015629]; anchored component of synaptic vesicle membrane [GO:0098993]; axon [GO:0030424]; axon terminus [GO:0043679]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic side of early endosome membrane [GO:0098559]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic early endosome [GO:0098842]; ruffle [GO:0001726]; somatodendritic compartment [GO:0036477]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1ueab__d2tmpa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; integrin binding [GO:0005178]; metalloendopeptidase inhibitor activity [GO:0008191]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; zinc ion binding [GO:0008270]; aging [GO:0007568]; central nervous system development [GO:0007417]; extracellular matrix disassembly [GO:0022617]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Ras protein signal transduction [GO:0046580]; neutrophil degranulation [GO:0043312]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; regulation of Rap protein signal transduction [GO:0032487]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to organic substance [GO:0010033]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	aging [GO:0007568]; central nervous system development [GO:0007417]; extracellular matrix disassembly [GO:0022617]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Ras protein signal transduction [GO:0046580]; neutrophil degranulation [GO:0043312]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; regulation of Rap protein signal transduction [GO:0032487]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to organic substance [GO:0010033]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	integrin binding [GO:0005178]; metalloendopeptidase inhibitor activity [GO:0008191]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; zinc ion binding [GO:0008270]
d1uead__d3i70a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	axon [GO:0030424]; basal part of cell [GO:0045178]; basement membrane [GO:0005604]; cell junction [GO:0030054]; extracellular matrix [GO:0031012]; extracellular matrix of synaptic cleft [GO:0098965]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; synapse [GO:0045202]; acetylcholine receptor regulator activity [GO:0030548]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; extracellular matrix binding [GO:0050840]; glycosaminoglycan binding [GO:0005539]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; laminin binding [GO:0043236]; laminin-1 binding [GO:0043237]; serine-type endopeptidase inhibitor activity [GO:0004867]; sialic acid binding [GO:0033691]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; negative regulation of neuron projection development [GO:0010977]; negative regulation of serine-type peptidase activity [GO:1902572]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; negative regulation of neuron projection development [GO:0010977]; negative regulation of serine-type peptidase activity [GO:1902572]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	axon [GO:0030424]; basal part of cell [GO:0045178]; basement membrane [GO:0005604]; cell junction [GO:0030054]; extracellular matrix [GO:0031012]; extracellular matrix of synaptic cleft [GO:0098965]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; synapse [GO:0045202]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	acetylcholine receptor regulator activity [GO:0030548]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; extracellular matrix binding [GO:0050840]; glycosaminoglycan binding [GO:0005539]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; laminin-1 binding [GO:0043237]; laminin binding [GO:0043236]; serine-type endopeptidase inhibitor activity [GO:0004867]; sialic acid binding [GO:0033691]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]
d1uefa1_d1qqga1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; intracellular signal transduction [GO:0035556]; macrophage colony-stimulating factor signaling pathway [GO:0038145]; negative regulation of MAPK cascade [GO:0043409]; Ras protein signal transduction [GO:0007265]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	caveola [GO:0005901]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; insulin receptor complex [GO:0005899]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; insulin receptor binding [GO:0005158]; insulin-like growth factor receptor binding [GO:0005159]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein kinase C binding [GO:0005080]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; cellular response to fatty acid [GO:0071398]; cellular response to insulin stimulus [GO:0032869]; glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; interleukin-7-mediated signaling pathway [GO:0038111]; MAPK cascade [GO:0000165]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of insulin secretion [GO:0046676]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase B signaling [GO:0051897]; response to insulin [GO:0032868]; response to peptide hormone [GO:0043434]; signal transduction [GO:0007165]	intracellular signal transduction [GO:0035556]; macrophage colony-stimulating factor signaling pathway [GO:0038145]; negative regulation of MAPK cascade [GO:0043409]; Ras protein signal transduction [GO:0007265]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cellular response to fatty acid [GO:0071398]; cellular response to insulin stimulus [GO:0032869]; glucose homeostasis [GO:0042593]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-7-mediated signaling pathway [GO:0038111]; MAPK cascade [GO:0000165]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of insulin secretion [GO:0046676]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase B signaling [GO:0051897]; response to insulin [GO:0032868]; response to peptide hormone [GO:0043434]; signal transduction [GO:0007165]	cytosol [GO:0005829]; nucleus [GO:0005634]	caveola [GO:0005901]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; insulin receptor complex [GO:0005899]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein kinase C binding [GO:0005080]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]
d1uepa1_d1n6dc1__1	Metazoa		Chordata	Euryarchaeota	bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; late endosome [GO:0005770]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; synapse [GO:0045202]; beta-1 adrenergic receptor binding [GO:0031697]; phosphatase binding [GO:0019902]; receptor signaling complex adaptor activity [GO:0030159]; SMAD binding [GO:0046332]; type II activin receptor binding [GO:0070699]; cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]	proteolysis [GO:0006508]	bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; late endosome [GO:0005770]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; synapse [GO:0045202]	cytoplasm [GO:0005737]	beta-1 adrenergic receptor binding [GO:0031697]; phosphatase binding [GO:0019902]; receptor signaling complex adaptor activity [GO:0030159]; SMAD binding [GO:0046332]; type II activin receptor binding [GO:0070699]	serine-type peptidase activity [GO:0008236]
d1ueqa1_d1tp5a2__1	Metazoa	Metazoa	Chordata	Chordata	bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; late endosome [GO:0005770]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; synapse [GO:0045202]; beta-1 adrenergic receptor binding [GO:0031697]; phosphatase binding [GO:0019902]; receptor signaling complex adaptor activity [GO:0030159]; SMAD binding [GO:0046332]; type II activin receptor binding [GO:0070699]; cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; late endosome [GO:0005770]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; synapse [GO:0045202]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	beta-1 adrenergic receptor binding [GO:0031697]; phosphatase binding [GO:0019902]; receptor signaling complex adaptor activity [GO:0030159]; SMAD binding [GO:0046332]; type II activin receptor binding [GO:0070699]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]
d1uera1_d2nybc1__1			Bacteroidetes	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]
d1uerc2_d2gdsa2__1		Metazoa	Bacteroidetes	Chordata	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1uerd1_d2gdsa1__1		Metazoa	Bacteroidetes	Chordata	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1uerd1_d4x9qa1__1		Metazoa	Bacteroidetes	Nematoda (roundworms)	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]		mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]
d1uesa2_d1ap6b2__1		Metazoa	Bacteroidetes	Chordata	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1uesb1_d1idsb1__1			Bacteroidetes	Actinobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1uesb1_d3lj9a1__1			Bacteroidetes	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1uesc2_d1xreb2__1			Bacteroidetes	Firmicutes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]			metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1uesd1_d2bpib1__1			Bacteroidetes	Apicomplexa	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ueta3_d3c66b3__1		Fungi	Euryarchaeota	Ascomycota	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]		mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d1uf2h2_d1bvp12__1					host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]; RNA binding [GO:0003723]	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]; host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]; fusion of virus membrane with host plasma membrane [GO:0019064]		fusion of virus membrane with host plasma membrane [GO:0019064]	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]	RNA binding [GO:0003723]	host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]
d1uf2p2_d5vjla___1				Negarnaviricota	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]; RNA binding [GO:0003723]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	RNA binding [GO:0003723]	host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d1uf5a__d5h8lc___1		Viridiplantae	Proteobacteria	Streptophyta	N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]; nitrogen compound metabolic process [GO:0006807]	N-carbamoylputrescine amidase activity [GO:0050126]; polyamine biosynthetic process [GO:0006596]	nitrogen compound metabolic process [GO:0006807]	polyamine biosynthetic process [GO:0006596]			N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]	N-carbamoylputrescine amidase activity [GO:0050126]
d1uf7a__d5h8jd___1		Viridiplantae	Proteobacteria	Streptophyta	N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]; nitrogen compound metabolic process [GO:0006807]	N-carbamoylputrescine amidase activity [GO:0050126]; polyamine biosynthetic process [GO:0006596]	nitrogen compound metabolic process [GO:0006807]	polyamine biosynthetic process [GO:0006596]			N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]	N-carbamoylputrescine amidase activity [GO:0050126]
d1uf8a__d1emsa2__1		Metazoa	Proteobacteria	Nematoda (roundworms)	N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]; nitrogen compound metabolic process [GO:0006807]	bis(5'-adenosyl)-triphosphatase activity [GO:0047710]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; nucleotide binding [GO:0000166]; nucleobase-containing compound metabolic process [GO:0006139]	nitrogen compound metabolic process [GO:0006807]	nucleobase-containing compound metabolic process [GO:0006139]			N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]	bis(5'-adenosyl)-triphosphatase activity [GO:0047710]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; nucleotide binding [GO:0000166]
d1ufba__d1wola___1			Deinococcus-Thermus	Crenarchaeota	phosphorelay signal transduction system [GO:0000160]		phosphorelay signal transduction system [GO:0000160]					
d1ufhb__d1y9wb___1			Firmicutes	Firmicutes	N-acetyltransferase activity [GO:0008080]	cytoplasm [GO:0005737]; N-acetyltransferase activity [GO:0008080]				cytoplasm [GO:0005737]	N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]
d1ufma1_d4cr2s2__1	Metazoa	Fungi	Chordata	Ascomycota	cell junction [GO:0030054]; COP9 signalosome [GO:0008180]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; synaptic vesicle [GO:0008021]; protein deneddylation [GO:0000338]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein deneddylation [GO:0000338]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cell junction [GO:0030054]; COP9 signalosome [GO:0008180]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; synaptic vesicle [GO:0008021]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ufya__d3quwa___1		Fungi	Deinococcus-Thermus	Ascomycota	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; deaminase activity [GO:0019239]; isoleucine biosynthetic process [GO:0009097]; mitochondrial translation [GO:0032543]; organonitrogen compound catabolic process [GO:1901565]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	isoleucine biosynthetic process [GO:0009097]; mitochondrial translation [GO:0032543]; organonitrogen compound catabolic process [GO:1901565]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	chorismate mutase activity [GO:0004106]	deaminase activity [GO:0019239]
d1ug9a1_d1lf6a1__1			Actinobacteria	Firmicutes	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]; polysaccharide metabolic process [GO:0005976]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; polysaccharide metabolic process [GO:0005976]	polysaccharide metabolic process [GO:0005976]	polysaccharide metabolic process [GO:0005976]			carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]
d1ug9a1_d4tf4b1__1			Actinobacteria	Actinobacteria	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]; polysaccharide metabolic process [GO:0005976]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	polysaccharide metabolic process [GO:0005976]	cellulose catabolic process [GO:0030245]			carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d1ug9a4_d1nsra1__1			Actinobacteria	Firmicutes	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]; polysaccharide metabolic process [GO:0005976]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	polysaccharide metabolic process [GO:0005976]	galactose metabolic process [GO:0006012]			carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1ugaa__d1muaa___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1ugba__d1koqb___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	periplasmic space [GO:0042597]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1ugqb__d3qz5d___1			Actinobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; nitrile hydratase activity [GO:0018822]; transition metal ion binding [GO:0046914]; nitrile catabolic process [GO:0050899]		nitrile catabolic process [GO:0050899]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; nitrile hydratase activity [GO:0018822]; transition metal ion binding [GO:0046914]	
d1ugsb__d2zpib___1			Actinobacteria	Actinobacteria	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; nitrile hydratase activity [GO:0018822]; transition metal ion binding [GO:0046914]; nitrile catabolic process [GO:0050899]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	nitrile catabolic process [GO:0050899]	nitrogen compound metabolic process [GO:0006807]			indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; nitrile hydratase activity [GO:0018822]; transition metal ion binding [GO:0046914]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d1ugua__d3umda___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d1ugw.3_d1j4tg___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1uh0.1_d1xxqd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1uh0.2_d1tp8.2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]
d1uh0.2_d3r51b___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1uh1.2_d5tqzc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]	carbohydrate binding [GO:0030246]
d1uh2a3_d2vl4a5__1			Firmicutes	Bacteroidetes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	beta-mannosidase activity [GO:0004567]
d1uh6a1_d4v3kb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein tag [GO:0031386]; cellular protein modification process [GO:0006464]; mRNA splicing, via spliceosome [GO:0000398]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein modification process [GO:0006464]; mRNA splicing, via spliceosome [GO:0000398]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	protein tag [GO:0031386]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1uhb.1_d1j8aa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1uhb.1_d5etxd1__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; transformation of host cell by virus [GO:0019087]	digestion [GO:0007586]; proteolysis [GO:0006508]	transformation of host cell by virus [GO:0019087]	extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d1uhia2_d5lpuc___1	Metazoa	Metazoa	Cnidaria	Chordata	calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	bioluminescence [GO:0008218]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]		collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium ion binding [GO:0005509]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d1uhka2_d4phja___1	Metazoa	Metazoa	Cnidaria	Chordata	calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	bioluminescence [GO:0008218]	cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d1uhkb2_d4pe0x___1	Metazoa	Metazoa	Cnidaria	Chordata	calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	bioluminescence [GO:0008218]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]		cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium ion binding [GO:0005509]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1uhta1_d2g1la1__1	Viridiplantae	Metazoa	Streptophyta	Chordata		axon [GO:0030424]; axon cytoplasm [GO:1904115]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; neuron projection [GO:0043005]; ATP binding [GO:0005524]; ATP-dependent microtubule motor activity, plus-end-directed [GO:0008574]; ATPase activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; motor activity [GO:0003774]; RNA binding [GO:0003723]; anterograde neuronal dense core vesicle transport [GO:1990048]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; retrograde neuronal dense core vesicle transport [GO:1990049]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192]		anterograde neuronal dense core vesicle transport [GO:1990048]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; retrograde neuronal dense core vesicle transport [GO:1990049]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192]		axon [GO:0030424]; axon cytoplasm [GO:1904115]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; neuron projection [GO:0043005]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; ATP-dependent microtubule motor activity, plus-end-directed [GO:0008574]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; motor activity [GO:0003774]; RNA binding [GO:0003723]
d1uhta1_d3po8a1__1	Viridiplantae		Streptophyta	Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; mRNA binding [GO:0003729]				cell wall [GO:0005618]; cytosol [GO:0005829]		mRNA binding [GO:0003729]
d1uhva2_d2d24a1__1			Firmicutes	Actinobacteria	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			xylan 1,4-beta-xylosidase activity [GO:0009044]	endo-1,4-beta-xylanase activity [GO:0031176]
d1uhvb2_d2bs9h2__1			Firmicutes	Firmicutes	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			xylan 1,4-beta-xylosidase activity [GO:0009044]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d1uhvd2_d3edjb2__1			Firmicutes	Bacteroidetes	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			xylan 1,4-beta-xylosidase activity [GO:0009044]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d1ui0a__d2sspe___1		Metazoa	Deinococcus-Thermus	Chordata	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; uracil DNA N-glycosylase activity [GO:0004844]; DNA repair [GO:0006281]	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	DNA repair [GO:0006281]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]		mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; uracil DNA N-glycosylase activity [GO:0004844]	damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]
d1ui8a3_d1a2vb3__1		Fungi	Actinobacteria	Ascomycota	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	peroxisome [GO:0005777]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]		peroxisome [GO:0005777]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d1uiaa__d1pzya___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1uiea__d4owba___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1uijb1_d4aq2b___1	Viridiplantae		Streptophyta	Proteobacteria	aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]		L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]	protein-DNA complex [GO:0032993]	nutrient reservoir activity [GO:0045735]	DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1uije1_d3balc___1	Viridiplantae		Streptophyta	Proteobacteria	aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]	acetylacetone-cleaving enzyme activity [GO:0033752]; metal ion binding [GO:0046872]			aleurone grain [GO:0033095]; endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]		nutrient reservoir activity [GO:0045735]	acetylacetone-cleaving enzyme activity [GO:0033752]; metal ion binding [GO:0046872]
d1uina__d1f2dc1__1		Fungi	Deinococcus-Thermus	Ascomycota	pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]; threonine biosynthetic process [GO:0009088]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]; amine catabolic process [GO:0009310]	threonine biosynthetic process [GO:0009088]	amine catabolic process [GO:0009310]			pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]; pyridoxal phosphate binding [GO:0030170]
d1uiqd__d1c9db___1				Proteobacteria		cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]		tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]
d1uirb__d1iy9d___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; spermine synthase activity [GO:0016768]; thermospermine synthase activity [GO:0010487]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; spermidine biosynthetic process [GO:0008295]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	spermidine biosynthetic process [GO:0008295]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; spermine synthase activity [GO:0016768]; thermospermine synthase activity [GO:0010487]	spermidine synthase activity [GO:0004766]
d1uiua__d3fatc1__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of synapse structure or activity [GO:0050803]; response to fungicide [GO:0060992]; synaptic transmission, glutamatergic [GO:0035249]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of synapse structure or activity [GO:0050803]; response to fungicide [GO:0060992]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; terminal bouton [GO:0043195]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]	AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1uiwc__d1fhjd___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1uiwd__d1ha7g___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1uiwg__d2bmma___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1uj3a1_d3myzb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1uj3a2_d2gj6b2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1uj3b1_d4x6ea2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1uj3b2_d3lhpl___1	Metazoa		Chordata		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]		activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]		cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]	
d1ujka__d4naca1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	nucleoplasm [GO:0005654]; RNA polymerase II, holoenzyme [GO:0016591]; identical protein binding [GO:0042802]; RNA polymerase II complex binding [GO:0000993]; dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; mRNA 3'-end processing [GO:0031124]; snRNA transcription by RNA polymerase II [GO:0042795]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; mRNA 3'-end processing [GO:0031124]; snRNA transcription by RNA polymerase II [GO:0042795]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	nucleoplasm [GO:0005654]; RNA polymerase II, holoenzyme [GO:0016591]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	identical protein binding [GO:0042802]; RNA polymerase II complex binding [GO:0000993]
d1ujoa1_d2dk9a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; actin filament binding [GO:0051015]; epithelial cell differentiation [GO:0030855]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; hippocampal mossy fiber expansion [GO:1990026]; intercellular bridge [GO:0045171]; intermediate filament [GO:0005882]; midbody [GO:0030496]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; SH3 domain binding [GO:0017124]; actin filament bundle assembly [GO:0051017]; actin filament depolymerization [GO:0030042]; blood coagulation [GO:0007596]; cytoskeleton organization [GO:0007010]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of protein phosphorylation [GO:0001933]; oxidation-reduction process [GO:0055114]; regulation of regulated secretory pathway [GO:1903305]; signal transduction [GO:0007165]; sulfur oxidation [GO:0019417]	epithelial cell differentiation [GO:0030855]	actin filament bundle assembly [GO:0051017]; actin filament depolymerization [GO:0030042]; blood coagulation [GO:0007596]; cytoskeleton organization [GO:0007010]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of protein phosphorylation [GO:0001933]; oxidation-reduction process [GO:0055114]; regulation of regulated secretory pathway [GO:1903305]; signal transduction [GO:0007165]; sulfur oxidation [GO:0019417]	cytoplasm [GO:0005737]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; hippocampal mossy fiber expansion [GO:1990026]; intercellular bridge [GO:0045171]; intermediate filament [GO:0005882]; midbody [GO:0030496]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; SH3 domain binding [GO:0017124]
d1ujua1_d1wh1a1__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; myelin sheath abaxonal region [GO:0035748]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Scrib-APC-beta-catenin complex [GO:0034750]; synapse [GO:0045202]; cadherin binding [GO:0045296]; activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; auditory receptor cell stereocilium organization [GO:0060088]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; post-anal tail morphogenesis [GO:0036342]; protein localization to adherens junction [GO:0071896]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; wound healing [GO:0042060]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; neuromuscular junction [GO:0031594]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567]	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; auditory receptor cell stereocilium organization [GO:0060088]; cell-cell adhesion [GO:0098609]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; post-anal tail morphogenesis [GO:0036342]; protein localization to adherens junction [GO:0071896]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; wound healing [GO:0042060]	neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567]	basolateral plasma membrane [GO:0016323]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; myelin sheath abaxonal region [GO:0035748]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Scrib-APC-beta-catenin complex [GO:0034750]; synapse [GO:0045202]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; neuromuscular junction [GO:0031594]	cadherin binding [GO:0045296]	ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1ujva1_d4jofb___1	Metazoa	Metazoa	Chordata	Chordata	bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; late endosome [GO:0005770]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; synapse [GO:0045202]; beta-1 adrenergic receptor binding [GO:0031697]; phosphatase binding [GO:0019902]; receptor signaling complex adaptor activity [GO:0030159]; SMAD binding [GO:0046332]; type II activin receptor binding [GO:0070699]; cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; late endosome [GO:0005770]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; synapse [GO:0045202]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	beta-1 adrenergic receptor binding [GO:0031697]; phosphatase binding [GO:0019902]; receptor signaling complex adaptor activity [GO:0030159]; SMAD binding [GO:0046332]; type II activin receptor binding [GO:0070699]	ion channel binding [GO:0044325]
d1uk1b1_d4paxa1__1	Metazoa	Metazoa	Chordata	Chordata	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA binding [GO:0003677]; NAD binding [GO:0051287]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]; ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]
d1ukca__d1lgyb___1	Fungi	Fungi	Ascomycota	Mucoromycota	hydrolase activity [GO:0016787]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]		extracellular space [GO:0005615]	hydrolase activity [GO:0016787]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d1ukcb__d1cusa___1	Fungi	Fungi	Ascomycota	Ascomycota	hydrolase activity [GO:0016787]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]				extracellular region [GO:0005576]	hydrolase activity [GO:0016787]	cutinase activity [GO:0050525]
d1ukcb__d1dt5c___1	Fungi	Fungi	Ascomycota	Ascomycota	hydrolase activity [GO:0016787]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]			hydrolase activity [GO:0016787]	triglyceride lipase activity [GO:0004806]
d1ukea__d2vp4d___1		Metazoa		Arthropoda	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; magnesium ion binding [GO:0000287]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; UMP kinase activity [GO:0033862]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; CDP biosynthetic process [GO:0046705]; nucleotide salvage [GO:0043173]; pyrimidine nucleobase salvage [GO:0043100]; UDP biosynthetic process [GO:0006225]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; CDP biosynthetic process [GO:0046705]; nucleotide salvage [GO:0043173]; pyrimidine nucleobase salvage [GO:0043100]; UDP biosynthetic process [GO:0006225]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; magnesium ion binding [GO:0000287]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; UMP kinase activity [GO:0033862]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]
d1ukea__d4o2lb___1		Metazoa		Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; magnesium ion binding [GO:0000287]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; UMP kinase activity [GO:0033862]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; CDP biosynthetic process [GO:0046705]; nucleotide salvage [GO:0043173]; pyrimidine nucleobase salvage [GO:0043100]; UDP biosynthetic process [GO:0006225]	cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; spliceosomal complex [GO:0005681]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein kinase binding [GO:0019901]; negative regulation of cold-induced thermogenesis [GO:0120163]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of TOR signaling [GO:0032008]; regulation of postsynapse organization [GO:0099175]; regulation of TOR signaling [GO:0032006]; regulation of type B pancreatic cell development [GO:2000074]; small GTPase mediated signal transduction [GO:0007264]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; CDP biosynthetic process [GO:0046705]; nucleotide salvage [GO:0043173]; pyrimidine nucleobase salvage [GO:0043100]; UDP biosynthetic process [GO:0006225]	negative regulation of cold-induced thermogenesis [GO:0120163]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of TOR signaling [GO:0032008]; regulation of postsynapse organization [GO:0099175]; regulation of TOR signaling [GO:0032006]; regulation of type B pancreatic cell development [GO:2000074]; small GTPase mediated signal transduction [GO:0007264]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; spliceosomal complex [GO:0005681]	ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; magnesium ion binding [GO:0000287]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; UMP kinase activity [GO:0033862]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein kinase binding [GO:0019901]
d1ukgb__d2exkc1__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1ukmb__d1jznb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1ukob__d3scqb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d1ukoc__d1a47a4__1	Viridiplantae		Streptophyta	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1ukod__d1eo5a4__1	Viridiplantae		Streptophyta	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1ukpd__d3hmca1__1	Viridiplantae		Streptophyta	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	polysaccharide catabolic process [GO:0000272]	cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]			amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	lysozyme activity [GO:0003796]
d1ukqa1_d1l9mb1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	carbohydrate metabolic process [GO:0005975]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]
d1ukqa2_d1j10d1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1ukqa4_d8cgta4__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1ukqb3_d1hvxa1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1ukqb4_d3a6ob3__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1ukra__d2vy0a___1	Fungi		Ascomycota	Euryarchaeota	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1ukrd__d5ik8a1__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	xylan catabolic process [GO:0045493]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	extracellular region [GO:0005576]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	endo-1,4-beta-xylanase activity [GO:0031176]	signaling receptor binding [GO:0005102]
d1uksa1_d5l2vb___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1uksa2_d2fhca3__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	plasma membrane [GO:0005886]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]
d1uktb1_d2w0pa___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	carbohydrate metabolic process [GO:0005975]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d1uktb3_d2zwzb2__1			Firmicutes	Thermotogae	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	extracellular region [GO:0005576]	lysosome [GO:0005764]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-L-fucosidase activity [GO:0004560]
d1uktb4_d1nm9a2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d1uktb4_d3ahxd___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1ukwa1_d5k3hb3__1		Metazoa	Deinococcus-Thermus	Nematoda (roundworms)	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]		ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]		peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]
d1ukwb1_d1rx0b1__1		Metazoa	Deinococcus-Thermus	Chordata	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	mitochondrial matrix [GO:0005759]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; branched-chain amino acid catabolic process [GO:0009083]; lipid metabolic process [GO:0006629]; valine catabolic process [GO:0006574]		branched-chain amino acid catabolic process [GO:0009083]; lipid metabolic process [GO:0006629]; valine catabolic process [GO:0006574]		mitochondrial matrix [GO:0005759]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d1ul1a1_d6ap4d3__1	Metazoa		Chordata	Proteobacteria	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; endonuclease activity [GO:0004519]; exonuclease activity [GO:0004527]; flap endonuclease activity [GO:0048256]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; memory [GO:0007613]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of sister chromatid cohesion [GO:0045876]; telomere maintenance via semi-conservative replication [GO:0032201]; UV protection [GO:0009650]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA replication [GO:0006260]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; memory [GO:0007613]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of sister chromatid cohesion [GO:0045876]; telomere maintenance via semi-conservative replication [GO:0032201]; UV protection [GO:0009650]	DNA replication [GO:0006260]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; endonuclease activity [GO:0004519]; exonuclease activity [GO:0004527]; flap endonuclease activity [GO:0048256]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1ul1c1_d4cs5c2__1	Metazoa	Metazoa	Chordata	Arthropoda	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; endonuclease activity [GO:0004519]; exonuclease activity [GO:0004527]; flap endonuclease activity [GO:0048256]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; memory [GO:0007613]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of sister chromatid cohesion [GO:0045876]; telomere maintenance via semi-conservative replication [GO:0032201]; UV protection [GO:0009650]	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; memory [GO:0007613]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of sister chromatid cohesion [GO:0045876]; telomere maintenance via semi-conservative replication [GO:0032201]; UV protection [GO:0009650]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleus [GO:0005634]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; endonuclease activity [GO:0004519]; exonuclease activity [GO:0004527]; flap endonuclease activity [GO:0048256]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d1ul1y1_d1b43b1__1	Metazoa		Chordata	Euryarchaeota	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; endonuclease activity [GO:0004519]; exonuclease activity [GO:0004527]; flap endonuclease activity [GO:0048256]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; memory [GO:0007613]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of sister chromatid cohesion [GO:0045876]; telomere maintenance via semi-conservative replication [GO:0032201]; UV protection [GO:0009650]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; memory [GO:0007613]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of sister chromatid cohesion [GO:0045876]; telomere maintenance via semi-conservative replication [GO:0032201]; UV protection [GO:0009650]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; endonuclease activity [GO:0004519]; exonuclease activity [GO:0004527]; flap endonuclease activity [GO:0048256]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]
d1ulaa__d3fnqc___1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]		drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d1ulcb__d1qmjb___1	Fungi	Metazoa	Basidiomycota	Chordata	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]	extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]			cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]
d1ulda__d2a3wd___1	Fungi	Metazoa	Basidiomycota	Chordata	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1uldb__d4bm8a1__1	Fungi	Metazoa	Basidiomycota	Chordata	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d1uldb__d5v38a1__1	Fungi		Basidiomycota	Firmicutes	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]	negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]		carbohydrate binding [GO:0030246]	
d1ulea__d5vkib___1	Fungi		Basidiomycota		cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]		permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	carbohydrate binding [GO:0030246]	
d1ulfb__d2phtb___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]			cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]		carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1ulgb__d5eyxa___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]			cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]		carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1ulgd__d1dzqc___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]			cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]		carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1ulic1_d1uuva1__1			Actinobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d1ulie1_d1z01b1__1			Actinobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d1ulie1_d3l72e2__1		Metazoa	Actinobacteria	Chordata	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	aromatic compound catabolic process [GO:0019439]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	biphenyl 2,3-dioxygenase activity [GO:0018687]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1ulja1_d2bmqa1__1			Actinobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]			biphenyl 2,3-dioxygenase activity [GO:0018687]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1uljb__d2gbwf___1			Actinobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]	aromatic compound catabolic process [GO:0019439]	cellular aromatic compound metabolic process [GO:0006725]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d1ulje1_d1z03c1__1			Actinobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d1ulje1_d4aayf___1			Actinobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]	aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]
d1ulpa__d2b4kc1__1			Actinobacteria	Proteobacteria	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	cellulose catabolic process [GO:0030245]				cellulase activity [GO:0008810]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d1ulqa1_d1m4sc2__1			Deinococcus-Thermus	Proteobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]		poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1ulqb1_d1zowa2__1			Deinococcus-Thermus	Firmicutes	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1ulqd1_d3ov2b1__1		Viridiplantae	Deinococcus-Thermus	Streptophyta	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]		flavonoid biosynthetic process [GO:0009813]			transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1ulqf1_d1tqyb2__1			Deinococcus-Thermus	Actinobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]		antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]			transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1ulqf1_d4ewpf1__1			Deinococcus-Thermus	Actinobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1ulqg1_d1pxtb2__1		Fungi	Deinococcus-Thermus	Ascomycota	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	mitochondrial intermembrane space [GO:0005758]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acetyl-CoA C-acyltransferase activity [GO:0003988]; mRNA binding [GO:0003729]; fatty acid beta-oxidation [GO:0006635]; phenylacetate catabolic process [GO:0010124]		fatty acid beta-oxidation [GO:0006635]; phenylacetate catabolic process [GO:0010124]		mitochondrial intermembrane space [GO:0005758]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acetyl-CoA C-acyltransferase activity [GO:0003988]; mRNA binding [GO:0003729]
d1ulqg2_d1oerc3__1			Deinococcus-Thermus		transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]						transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	
d1ulqh2_d2bz3c1__1			Deinococcus-Thermus	Proteobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1ulra__d1urra___1		Metazoa	Deinococcus-Thermus	Arthropoda	acylphosphatase activity [GO:0003998]	cytoplasm [GO:0005737]; acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]; cellular metabolic process [GO:0044237]		cellular metabolic process [GO:0044237]		cytoplasm [GO:0005737]	acylphosphatase activity [GO:0003998]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]
d1ulra__d4ojhb___1			Deinococcus-Thermus	Crenarchaeota	acylphosphatase activity [GO:0003998]	acylphosphatase activity [GO:0003998]					acylphosphatase activity [GO:0003998]	acylphosphatase activity [GO:0003998]
d1ulva1_d1lf9a1__1			Actinobacteria	Firmicutes	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]; polysaccharide metabolic process [GO:0005976]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; polysaccharide metabolic process [GO:0005976]	polysaccharide metabolic process [GO:0005976]	polysaccharide metabolic process [GO:0005976]			carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]
d1ulva2_d1ji1b1__1			Actinobacteria	Firmicutes	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]; polysaccharide metabolic process [GO:0005976]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	polysaccharide metabolic process [GO:0005976]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1ulva2_d1vfma1__1			Actinobacteria	Firmicutes	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]; polysaccharide metabolic process [GO:0005976]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	polysaccharide metabolic process [GO:0005976]	carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1ulza2_d3g8cb1__1			Aquificae	Proteobacteria	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]		fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d1um0c__d1umfa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; chorismate synthase activity [GO:0004107]; FMN binding [GO:0010181]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; chorismate synthase activity [GO:0004107]; FMN binding [GO:0010181]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]	cytosol [GO:0005829]	chorismate synthase activity [GO:0004107]; FMN binding [GO:0010181]	chorismate synthase activity [GO:0004107]; FMN binding [GO:0010181]
d1um1a1_d4uu6a___1	Metazoa	Metazoa	Chordata	Chordata	microtubule [GO:0005874]; protein-containing complex [GO:0032991]; multicellular organism development [GO:0007275]; signal transduction [GO:0007165]; substrate adhesion-dependent cell spreading [GO:0034446]	apical plasma membrane [GO:0016324]; axon [GO:0030424]; bicellular tight junction [GO:0005923]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; lateral loop [GO:0043219]; myelin sheath adaxonal region [GO:0035749]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schmidt-Lanterman incisure [GO:0043220]; ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; bicellular tight junction assembly [GO:0070830]; establishment of epithelial cell polarity [GO:0090162]; morphogenesis of an epithelial sheet [GO:0002011]; myelin assembly [GO:0032288]; peripheral nervous system myelin maintenance [GO:0032287]; protein localization to myelin sheath abaxonal region [GO:0035750]; protein localization to plasma membrane [GO:0072659]	multicellular organism development [GO:0007275]; signal transduction [GO:0007165]; substrate adhesion-dependent cell spreading [GO:0034446]	bicellular tight junction assembly [GO:0070830]; establishment of epithelial cell polarity [GO:0090162]; morphogenesis of an epithelial sheet [GO:0002011]; myelin assembly [GO:0032288]; peripheral nervous system myelin maintenance [GO:0032287]; protein localization to myelin sheath abaxonal region [GO:0035750]; protein localization to plasma membrane [GO:0072659]	microtubule [GO:0005874]; protein-containing complex [GO:0032991]	apical plasma membrane [GO:0016324]; axon [GO:0030424]; bicellular tight junction [GO:0005923]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; lateral loop [GO:0043219]; myelin sheath adaxonal region [GO:0035749]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schmidt-Lanterman incisure [GO:0043220]		ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]
d1um4h1_d1uwex1__1	Metazoa		Chordata									
d1um4h2_d1ncwl2__1	Metazoa	Metazoa	Chordata	Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d1um4h2_d3fctc1__1	Metazoa		Chordata									
d1um4l1_d3g6dl2__1	Metazoa	Metazoa	Chordata	Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]
d1um5h1_d2xqyl2__1	Metazoa		Chordata			host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; fusion of virus membrane with host plasma membrane [GO:0019064]		fusion of virus membrane with host plasma membrane [GO:0019064]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		
d1um6h2_d1kfal1__1	Metazoa		Chordata									
d1um6l1_d4khtl1__1	Metazoa		Chordata			viral envelope [GO:0019031]; structural molecule activity [GO:0005198]				viral envelope [GO:0019031]		structural molecule activity [GO:0005198]
d1um6l1_d5lmja1__1	Metazoa		Chordata									
d1um9b1_d3exgn1__1		Metazoa	Deinococcus-Thermus	Chordata	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1umbb1_d1y9db3__1			Deinococcus-Thermus	Firmicutes	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]					3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d1umbc__d2g25b1__1			Deinococcus-Thermus	Proteobacteria	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytosol [GO:0005829]; membrane [GO:0016020]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]
d1umbd2_d5hhta3__1			Deinococcus-Thermus	Proteobacteria	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d1umcc__d4jubd1__1			Deinococcus-Thermus	Proteobacteria	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1umda__d5k6ta3__1		Viridiplantae	Deinococcus-Thermus	Streptophyta	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]		isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1umdb1_d1w88b1__1			Deinococcus-Thermus	Firmicutes	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]			3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1umdc__d2ihvd2__1			Deinococcus-Thermus	Actinobacteria	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]					3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]
d1umdd2_d5hgxa3__1		Fungi	Deinococcus-Thermus	Ascomycota	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]					3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1umia1_d5ofia___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; organelle membrane [GO:0031090]; SCF ubiquitin ligase complex [GO:0019005]; amyloid-beta binding [GO:0001540]; carbohydrate binding [GO:0030246]; glycoprotein catabolic process [GO:0006516]; negative regulation of cell population proliferation [GO:0008285]; protein ubiquitination [GO:0016567]; regulation of protein ubiquitination [GO:0031396]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	glycoprotein catabolic process [GO:0006516]; negative regulation of cell population proliferation [GO:0008285]; protein ubiquitination [GO:0016567]; regulation of protein ubiquitination [GO:0031396]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; organelle membrane [GO:0031090]; SCF ubiquitin ligase complex [GO:0019005]		amyloid-beta binding [GO:0001540]; carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1umja__d3aa9b___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; metal ion binding [GO:0046872]; protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	response to metal ion [GO:0010038]	protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; metal ion binding [GO:0046872]
d1umjb__d1naqb___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; metal ion binding [GO:0046872]; protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	response to metal ion [GO:0010038]	protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; metal ion binding [GO:0046872]
d1umka1_d5h5jc1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; AMP binding [GO:0016208]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; NAD binding [GO:0051287]; blood circulation [GO:0008015]; cholesterol biosynthetic process [GO:0006695]; L-ascorbic acid metabolic process [GO:0019852]; neutrophil degranulation [GO:0043312]; xenobiotic metabolic process [GO:0006805]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	blood circulation [GO:0008015]; cholesterol biosynthetic process [GO:0006695]; L-ascorbic acid metabolic process [GO:0019852]; neutrophil degranulation [GO:0043312]; xenobiotic metabolic process [GO:0006805]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	chloroplast [GO:0009507]	ADP binding [GO:0043531]; AMP binding [GO:0016208]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; NAD binding [GO:0051287]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d1umka2_d1ogia2__1	Metazoa		Chordata	Cyanobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; AMP binding [GO:0016208]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; NAD binding [GO:0051287]; blood circulation [GO:0008015]; cholesterol biosynthetic process [GO:0006695]; L-ascorbic acid metabolic process [GO:0019852]; neutrophil degranulation [GO:0043312]; xenobiotic metabolic process [GO:0006805]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	blood circulation [GO:0008015]; cholesterol biosynthetic process [GO:0006695]; L-ascorbic acid metabolic process [GO:0019852]; neutrophil degranulation [GO:0043312]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	phycobilisome [GO:0030089]	ADP binding [GO:0043531]; AMP binding [GO:0016208]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; NAD binding [GO:0051287]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d1umla__d3hk9c___1	Metazoa		Chordata	Firmicutes	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]; adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	metal ion binding [GO:0046872]	adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]		cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]		adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1umnc__d1ji4j___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1umng__d3oj5a___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d1umng__d4xkti___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1umnh__d1qghb___1			Firmicutes	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1umnk__d4to9e___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1umnl__d4toed___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1umoa__d3wctd___1	Metazoa	Metazoa	Chordata	Annelida	cytosol [GO:0005829]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]; fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1umob__d4jyqa___1	Metazoa	Metazoa	Chordata	Annelida	cytosol [GO:0005829]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]; fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]		catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d1umpa2_d1w6ka2__1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; membrane [GO:0016020]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; cholesterol biosynthetic process [GO:0006695]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of protein stability [GO:0031647]; steroid biosynthetic process [GO:0006694]; triterpenoid biosynthetic process [GO:0016104]	hopanoid biosynthetic process [GO:0019746]	cholesterol biosynthetic process [GO:0006695]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of protein stability [GO:0031647]; steroid biosynthetic process [GO:0006694]; triterpenoid biosynthetic process [GO:0016104]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; membrane [GO:0016020]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]
d1umpb2_d1jcqb___1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]; protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]; protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	hopanoid biosynthetic process [GO:0019746]	protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]
d1umra__d3p5fc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]		antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	extracellular region [GO:0005576]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1umrb__d2cl8a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]		cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	extracellular region [GO:0005576]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1umrc__d1kmb11__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]		complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	toxin activity [GO:0090729]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d1umrd__d4gjxc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d1umsa__d2wo9d___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1umsa__d4fkka2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1umvx__d1fv0a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]; regulation of blood pressure [GO:0008217]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]; regulation of blood pressure [GO:0008217]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1umwb1_d1q4oa2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]; anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]; anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]	anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]	anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]
d1umza__d1u0ad___1	Viridiplantae		Streptophyta	Firmicutes	apoplast [GO:0048046]; cell wall [GO:0005618]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]; cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]	carbohydrate metabolic process [GO:0005975]	apoplast [GO:0048046]; cell wall [GO:0005618]		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]	licheninase activity [GO:0042972]
d1umza__d2phrb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	apoplast [GO:0048046]; cell wall [GO:0005618]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]; cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]		apoplast [GO:0048046]; cell wall [GO:0005618]		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1un1b__d2zmkd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	apoplast [GO:0048046]; cell wall [GO:0005618]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]; cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]	carbohydrate binding [GO:0030246]	cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]		apoplast [GO:0048046]; cell wall [GO:0005618]		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]	carbohydrate binding [GO:0030246]
d1un8a4_d3pnkb___1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; glycerone kinase activity [GO:0004371]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; anaerobic glycerol catabolic process [GO:0019588]	cytosol [GO:0005829]; glycerone kinase activity [GO:0004371]; identical protein binding [GO:0042802]; phosphoenolpyruvate-glycerone phosphotransferase activity [GO:0047324]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol to glycerone phosphate metabolic process [GO:0061610]; ketone catabolic process [GO:0042182]; monosaccharide catabolic process [GO:0046365]	anaerobic glycerol catabolic process [GO:0019588]	cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol to glycerone phosphate metabolic process [GO:0061610]; ketone catabolic process [GO:0042182]; monosaccharide catabolic process [GO:0046365]		cytosol [GO:0005829]	ATP binding [GO:0005524]; glycerone kinase activity [GO:0004371]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	glycerone kinase activity [GO:0004371]; identical protein binding [GO:0042802]; phosphoenolpyruvate-glycerone phosphotransferase activity [GO:0047324]
d1un9b4_d3fysa1__1			Proteobacteria	Firmicutes	ATP binding [GO:0005524]; glycerone kinase activity [GO:0004371]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; anaerobic glycerol catabolic process [GO:0019588]	lipid binding [GO:0008289]	anaerobic glycerol catabolic process [GO:0019588]				ATP binding [GO:0005524]; glycerone kinase activity [GO:0004371]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	lipid binding [GO:0008289]
d1ungd__d2i53a2__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; protein kinase 5 complex [GO:0016533]; actin filament binding [GO:0051015]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; ephrin receptor binding [GO:0046875]; ionotropic glutamate receptor binding [GO:0035255]; kinase activity [GO:0016301]; protease binding [GO:0002020]; protein kinase activator activity [GO:0030295]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; brain development [GO:0007420]; cerebellum development [GO:0021549]; embryo development ending in birth or egg hatching [GO:0009792]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; layer formation in cerebral cortex [GO:0021819]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of axon extension [GO:0030517]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of receptor biosynthetic process [GO:0010870]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of macroautophagy [GO:0016241]; regulation of neuron differentiation [GO:0045664]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of synaptic vesicle cycle [GO:0098693]; rhythmic process [GO:0048511]; serine phosphorylation of STAT protein [GO:0042501]; superior olivary nucleus maturation [GO:0021722]	cyclin K-CDK12 complex [GO:0002944]; cyclin K-CDK13 complex [GO:0002945]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cell cycle arrest [GO:0071157]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues [GO:2001165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; brain development [GO:0007420]; cerebellum development [GO:0021549]; embryo development ending in birth or egg hatching [GO:0009792]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; layer formation in cerebral cortex [GO:0021819]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of axon extension [GO:0030517]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of receptor biosynthetic process [GO:0010870]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of macroautophagy [GO:0016241]; regulation of neuron differentiation [GO:0045664]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of synaptic vesicle cycle [GO:0098693]; rhythmic process [GO:0048511]; serine phosphorylation of STAT protein [GO:0042501]; superior olivary nucleus maturation [GO:0021722]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cell cycle arrest [GO:0071157]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues [GO:2001165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	axon [GO:0030424]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; protein kinase 5 complex [GO:0016533]	cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin K-CDK12 complex [GO:0002944]; cyclin K-CDK13 complex [GO:0002945]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	actin filament binding [GO:0051015]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; ephrin receptor binding [GO:0046875]; ionotropic glutamate receptor binding [GO:0035255]; kinase activity [GO:0016301]; protease binding [GO:0002020]; protein kinase activator activity [GO:0030295]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]	cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]
d1unkc__d4uhpd___1			Proteobacteria	Proteobacteria	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]			toxic substance binding [GO:0015643]	toxic substance binding [GO:0015643]
d1unna1_d1vymc1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d1unnb1_d5wceb2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1unnb2_d4l6pc2__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]
d1unnc1_d1t3na1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytoplasmic ribonucleoprotein granule [GO:0036464]; intracellular [GO:0005622]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytoplasmic ribonucleoprotein granule [GO:0036464]; intracellular [GO:0005622]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d1unqa__d5ncfb___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; vesicle [GO:0031982]; 14-3-3 protein binding [GO:0071889]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein phosphatase 2A binding [GO:0051721]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; activation of protein kinase B activity [GO:0032148]; activation-induced cell death of T cells [GO:0006924]; aging [GO:0007568]; anoikis [GO:0043276]; apoptotic mitochondrial changes [GO:0008637]; carbohydrate transport [GO:0008643]; cell differentiation [GO:0030154]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell population proliferation [GO:0008283]; cell projection organization [GO:0030030]; cellular protein modification process [GO:0006464]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidised low-density lipoprotein particle stimulus [GO:0140052]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; endocrine pancreas development [GO:0031018]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization to mitochondrion [GO:0072655]; excitatory postsynaptic potential [GO:0060079]; execution phase of apoptosis [GO:0097194]; G protein-coupled receptor signaling pathway [GO:0007186]; germ cell development [GO:0007281]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen cell differentiation involved in embryonic placenta development [GO:0060709]; hyaluronan metabolic process [GO:0030212]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; interleukin-18-mediated signaling pathway [GO:0035655]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; maintenance of protein location in mitochondrion [GO:0072656]; mammary gland epithelial cell differentiation [GO:0060644]; maternal placenta development [GO:0001893]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of lymphocyte migration [GO:2000402]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase activity by protein phosphorylation [GO:0100002]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of proteolysis [GO:0045861]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; NIK/NF-kappaB signaling [GO:0038061]; nitric oxide biosynthetic process [GO:0006809]; osteoblast differentiation [GO:0001649]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peripheral nervous system myelin maintenance [GO:0032287]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphorylation [GO:0016310]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of organ growth [GO:0046622]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of mRNA stability [GO:0043488]; regulation of myelination [GO:0031641]; regulation of neuron projection development [GO:0010975]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of translation [GO:0006417]; response to fluid shear stress [GO:0034405]; response to food [GO:0032094]; response to growth hormone [GO:0060416]; response to heat [GO:0009408]; response to insulin-like growth factor stimulus [GO:1990418]; response to oxidative stress [GO:0006979]; response to UV-A [GO:0070141]; signal transduction [GO:0007165]; spinal cord development [GO:0021510]; striated muscle cell differentiation [GO:0051146]; T cell costimulation [GO:0031295]; TOR signaling [GO:0031929]; translation [GO:0006412]	cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; synapse [GO:0045202]; actin binding [GO:0003779]; profilin binding [GO:0005522]; SH3 domain binding [GO:0017124]; WW domain binding [GO:0050699]; actin polymerization or depolymerization [GO:0008154]; actin polymerization-dependent cell motility [GO:0070358]; axon guidance [GO:0007411]	activation-induced cell death of T cells [GO:0006924]; activation of protein kinase B activity [GO:0032148]; aging [GO:0007568]; anoikis [GO:0043276]; apoptotic mitochondrial changes [GO:0008637]; carbohydrate transport [GO:0008643]; cell differentiation [GO:0030154]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell population proliferation [GO:0008283]; cell projection organization [GO:0030030]; cellular protein modification process [GO:0006464]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidised low-density lipoprotein particle stimulus [GO:0140052]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; endocrine pancreas development [GO:0031018]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization to mitochondrion [GO:0072655]; excitatory postsynaptic potential [GO:0060079]; execution phase of apoptosis [GO:0097194]; germ cell development [GO:0007281]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen cell differentiation involved in embryonic placenta development [GO:0060709]; G protein-coupled receptor signaling pathway [GO:0007186]; hyaluronan metabolic process [GO:0030212]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-18-mediated signaling pathway [GO:0035655]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; maintenance of protein location in mitochondrion [GO:0072656]; mammary gland epithelial cell differentiation [GO:0060644]; maternal placenta development [GO:0001893]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of lymphocyte migration [GO:2000402]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase activity by protein phosphorylation [GO:0100002]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of proteolysis [GO:0045861]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; NIK/NF-kappaB signaling [GO:0038061]; nitric oxide biosynthetic process [GO:0006809]; osteoblast differentiation [GO:0001649]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peripheral nervous system myelin maintenance [GO:0032287]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphorylation [GO:0016310]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of organ growth [GO:0046622]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of mRNA stability [GO:0043488]; regulation of myelination [GO:0031641]; regulation of neuron projection development [GO:0010975]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of translation [GO:0006417]; response to fluid shear stress [GO:0034405]; response to food [GO:0032094]; response to growth hormone [GO:0060416]; response to heat [GO:0009408]; response to insulin-like growth factor stimulus [GO:1990418]; response to oxidative stress [GO:0006979]; response to UV-A [GO:0070141]; signal transduction [GO:0007165]; spinal cord development [GO:0021510]; striated muscle cell differentiation [GO:0051146]; T cell costimulation [GO:0031295]; TOR signaling [GO:0031929]; translation [GO:0006412]	actin polymerization-dependent cell motility [GO:0070358]; actin polymerization or depolymerization [GO:0008154]; axon guidance [GO:0007411]	cell-cell junction [GO:0005911]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; vesicle [GO:0031982]	cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; synapse [GO:0045202]	14-3-3 protein binding [GO:0071889]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein phosphatase 2A binding [GO:0051721]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]	actin binding [GO:0003779]; profilin binding [GO:0005522]; SH3 domain binding [GO:0017124]; WW domain binding [GO:0050699]
d1uo6a__d2h5ca___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1uoha__d3twsc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription factor binding [GO:0008134]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; apoptotic process [GO:0006915]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; post-translational protein modification [GO:0043687]; proteasome regulatory particle assembly [GO:0070682]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; apoptotic process [GO:0006915]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; post-translational protein modification [GO:0043687]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; proteasome regulatory particle assembly [GO:0070682]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription factor binding [GO:0008134]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]
d1uoja__d1kgyc___1		Metazoa	Proteobacteria	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]	carbohydrate binding [GO:0030246]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1uojb__d3cqoa2__1		Metazoa	Proteobacteria	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	metal ion binding [GO:0046872]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]		carbohydrate binding [GO:0030246]	metal ion binding [GO:0046872]
d1uojd__d4xupc___1			Proteobacteria	Firmicutes	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	xylan catabolic process [GO:0045493]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]		carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d1uoka1_d1m53a1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; oligo-1,6-glucosidase activity [GO:0004574]; carbohydrate metabolic process [GO:0005975]	catalytic activity [GO:0003824]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; oligo-1,6-glucosidase activity [GO:0004574]	catalytic activity [GO:0003824]
d1uopa2_d4an0a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d1uoqa2_d1e5ta2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d1uora2_d4or0a3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d1uosc__d3bbsa___1	Metazoa		Chordata		extracellular region [GO:0005576]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		toxin activity [GO:0090729]	
d1uosd__d1f02i3__1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	toxin activity [GO:0090729]	
d1uova1_d5lowj___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	actin cytoskeleton [GO:0015629]; anchored component of presynaptic membrane [GO:0099026]; axon [GO:0030424]; axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; intracellular organelle [GO:0043229]; lamellipodium [GO:0030027]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; SNARE complex [GO:0031201]; synaptobrevin 2-SNAP-25-syntaxin-1a complex [GO:0070044]; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex [GO:0070032]; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex [GO:0070033]; terminal bouton [GO:0043195]; voltage-gated potassium channel complex [GO:0008076]; calcium-dependent protein binding [GO:0048306]; ion channel binding [GO:0044325]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; voltage-gated potassium channel activity [GO:0005249]; axonogenesis [GO:0007409]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; endosomal transport [GO:0016197]; exocytosis [GO:0006887]; growth hormone secretion [GO:0030252]; long-term memory [GO:0007616]; neuron differentiation [GO:0030182]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin secretion [GO:0032024]; regulation of neuron projection development [GO:0010975]; regulation of synapse assembly [GO:0051963]; sleep [GO:0030431]; SNARE complex assembly [GO:0035493]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; vesicle fusion [GO:0006906]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	axonogenesis [GO:0007409]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; endosomal transport [GO:0016197]; exocytosis [GO:0006887]; growth hormone secretion [GO:0030252]; long-term memory [GO:0007616]; neuron differentiation [GO:0030182]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin secretion [GO:0032024]; regulation of neuron projection development [GO:0010975]; regulation of synapse assembly [GO:0051963]; sleep [GO:0030431]; SNARE complex assembly [GO:0035493]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; vesicle fusion [GO:0006906]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	actin cytoskeleton [GO:0015629]; anchored component of presynaptic membrane [GO:0099026]; axon [GO:0030424]; axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; intracellular organelle [GO:0043229]; lamellipodium [GO:0030027]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; SNARE complex [GO:0031201]; synaptobrevin 2-SNAP-25-syntaxin-1a complex [GO:0070044]; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex [GO:0070032]; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex [GO:0070033]; terminal bouton [GO:0043195]; voltage-gated potassium channel complex [GO:0008076]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]	calcium-dependent protein binding [GO:0048306]; ion channel binding [GO:0044325]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin binding [GO:0019905]; voltage-gated potassium channel activity [GO:0005249]
d1uoxa1_d4r99c1__1				Firmicutes								
d1uoza1_d4a05a___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	cellulase activity [GO:0008810]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1up1a2_d2adba1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]
d1up1a2_d2leaa___1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]
d1up6a1_d2ldxd1__1		Metazoa	Thermotogae	Chordata	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]	cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]; L-lactate dehydrogenase activity [GO:0004459]; ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]	carbohydrate metabolic process [GO:0005975]	ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]		cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	L-lactate dehydrogenase activity [GO:0004459]
d1up6f1_d1pgjb2__1			Thermotogae		6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; glycosome [GO:0020015]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]	D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]		ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; glycosome [GO:0020015]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]
d1up7b1_d1yded___1		Metazoa	Thermotogae	Chordata	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	carbohydrate metabolic process [GO:0005975]	estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]		cytosol [GO:0005829]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]
d1up8a__d1vnha___1		Fungi	Rhodophyta	Ascomycota	metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	extracellular region [GO:0005576]; chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]				extracellular region [GO:0005576]	metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]
d1up9a__d1j0pa___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]		anaerobic respiration [GO:0009061]		periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1upba3_d5hhtb2__1			Actinobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d1upbd3_d5hhta1__1			Actinobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d1upcb1_d6eo0a1__1		Metazoa	Actinobacteria	Chordata	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl binding [GO:0000035]; heterocyclic compound binding [GO:1901363]; NAD+ binding [GO:0070403]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]; peptidyl-lysine demalonylation [GO:0036047]; peptidyl-lysine desuccinylation [GO:0036049]; protein desuccinylation [GO:0036048]; regulation of ketone biosynthetic process [GO:0010566]		peptidyl-lysine demalonylation [GO:0036047]; peptidyl-lysine desuccinylation [GO:0036049]; protein desuccinylation [GO:0036048]; regulation of ketone biosynthetic process [GO:0010566]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	acyl binding [GO:0000035]; heterocyclic compound binding [GO:1901363]; NAD+ binding [GO:0070403]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d1upcc1_d4ig9a1__1		Metazoa	Actinobacteria	Chordata	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	cell [GO:0005623]; chromatin silencing complex [GO:0005677]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear envelope [GO:0005635]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nuclear inner membrane [GO:0005637]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; rDNA heterochromatin [GO:0033553]; bHLH transcription factor binding [GO:0043425]; deacetylase activity [GO:0019213]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; histone binding [GO:0042393]; histone deacetylase activity [GO:0004407]; HLH domain binding [GO:0043398]; identical protein binding [GO:0042802]; keratin filament binding [GO:1990254]; metal ion binding [GO:0046872]; mitogen-activated protein kinase binding [GO:0051019]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone deacetylase activity (H3-K9 specific) [GO:0046969]; NAD-dependent protein deacetylase activity [GO:0034979]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein C-terminus binding [GO:0008022]; protein deacetylase activity [GO:0033558]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transferase activity [GO:0016740]; angiogenesis [GO:0001525]; behavioral response to starvation [GO:0042595]; cell aging [GO:0007569]; cellular glucose homeostasis [GO:0001678]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; circadian regulation of gene expression [GO:0032922]; DNA synthesis involved in DNA repair [GO:0000731]; establishment of chromatin silencing [GO:0006343]; fatty acid homeostasis [GO:0055089]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; leptin-mediated signaling pathway [GO:0033210]; macrophage cytokine production [GO:0010934]; macrophage differentiation [GO:0030225]; maintenance of chromatin silencing [GO:0006344]; methylation-dependent chromatin silencing [GO:0006346]; muscle organ development [GO:0007517]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of cell growth [GO:0030308]; negative regulation of cellular response to testosterone stimulus [GO:2000655]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of helicase activity [GO:0051097]; negative regulation of histone H3-K14 acetylation [GO:0071441]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of neuron death [GO:1901215]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; ovulation from ovarian follicle [GO:0001542]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA repair [GO:0045739]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of macroautophagy [GO:0016239]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell differentiation [GO:0051152]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of apoptotic process [GO:0042981]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of brown fat cell differentiation [GO:0090335]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of endodeoxyribonuclease activity [GO:0032071]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid storage [GO:0010883]; regulation of mitotic cell cycle [GO:0007346]; regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035358]; regulation of protein serine/threonine kinase activity [GO:0071900]; regulation of smooth muscle cell apoptotic process [GO:0034391]; response to hydrogen peroxide [GO:0042542]; response to insulin [GO:0032868]; response to leptin [GO:0044321]; response to oxidative stress [GO:0006979]; single strand break repair [GO:0000012]; spermatogenesis [GO:0007283]; stress-induced premature senescence [GO:0090400]; transforming growth factor beta receptor signaling pathway [GO:0007179]; triglyceride mobilization [GO:0006642]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; white fat cell differentiation [GO:0050872]		angiogenesis [GO:0001525]; behavioral response to starvation [GO:0042595]; cell aging [GO:0007569]; cellular glucose homeostasis [GO:0001678]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; circadian regulation of gene expression [GO:0032922]; DNA synthesis involved in DNA repair [GO:0000731]; establishment of chromatin silencing [GO:0006343]; fatty acid homeostasis [GO:0055089]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; leptin-mediated signaling pathway [GO:0033210]; macrophage cytokine production [GO:0010934]; macrophage differentiation [GO:0030225]; maintenance of chromatin silencing [GO:0006344]; methylation-dependent chromatin silencing [GO:0006346]; muscle organ development [GO:0007517]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of cell growth [GO:0030308]; negative regulation of cellular response to testosterone stimulus [GO:2000655]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of helicase activity [GO:0051097]; negative regulation of histone H3-K14 acetylation [GO:0071441]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of neuron death [GO:1901215]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; ovulation from ovarian follicle [GO:0001542]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA repair [GO:0045739]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of macroautophagy [GO:0016239]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell differentiation [GO:0051152]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of apoptotic process [GO:0042981]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of brown fat cell differentiation [GO:0090335]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of endodeoxyribonuclease activity [GO:0032071]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid storage [GO:0010883]; regulation of mitotic cell cycle [GO:0007346]; regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035358]; regulation of protein serine/threonine kinase activity [GO:0071900]; regulation of smooth muscle cell apoptotic process [GO:0034391]; response to hydrogen peroxide [GO:0042542]; response to insulin [GO:0032868]; response to leptin [GO:0044321]; response to oxidative stress [GO:0006979]; single strand break repair [GO:0000012]; spermatogenesis [GO:0007283]; stress-induced premature senescence [GO:0090400]; transforming growth factor beta receptor signaling pathway [GO:0007179]; triglyceride mobilization [GO:0006642]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; white fat cell differentiation [GO:0050872]		cell [GO:0005623]; chromatin silencing complex [GO:0005677]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear envelope [GO:0005635]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nuclear inner membrane [GO:0005637]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; rDNA heterochromatin [GO:0033553]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	bHLH transcription factor binding [GO:0043425]; deacetylase activity [GO:0019213]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; histone binding [GO:0042393]; histone deacetylase activity [GO:0004407]; HLH domain binding [GO:0043398]; identical protein binding [GO:0042802]; keratin filament binding [GO:1990254]; metal ion binding [GO:0046872]; mitogen-activated protein kinase binding [GO:0051019]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone deacetylase activity (H3-K9 specific) [GO:0046969]; NAD-dependent protein deacetylase activity [GO:0034979]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein C-terminus binding [GO:0008022]; protein deacetylase activity [GO:0033558]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transferase activity [GO:0016740]
d1upcc3_d5fema1__1		Fungi	Actinobacteria	Ascomycota	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1upcd3_d1y9dc3__1			Actinobacteria	Firmicutes	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d1upce1_d6eo0d1__1		Metazoa	Actinobacteria	Chordata	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl binding [GO:0000035]; heterocyclic compound binding [GO:1901363]; NAD+ binding [GO:0070403]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]; peptidyl-lysine demalonylation [GO:0036047]; peptidyl-lysine desuccinylation [GO:0036049]; protein desuccinylation [GO:0036048]; regulation of ketone biosynthetic process [GO:0010566]		peptidyl-lysine demalonylation [GO:0036047]; peptidyl-lysine desuccinylation [GO:0036049]; protein desuccinylation [GO:0036048]; regulation of ketone biosynthetic process [GO:0010566]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	acyl binding [GO:0000035]; heterocyclic compound binding [GO:1901363]; NAD+ binding [GO:0070403]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d1upce3_d2fn3a2__1			Actinobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1upcf1_d1m2ha1__1			Actinobacteria	Euryarchaeota	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]				cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d1upfb__d2e55b___1			Apicomplexa	Aquificae	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	cytosol [GO:0005829]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]		cytosol [GO:0005829]	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]
d1upmb1_d3wqpd1__1	Viridiplantae		Streptophyta	Euryarchaeota	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1upmc__d3axmz___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1upmh1_d3a13g1__1	Viridiplantae		Streptophyta	Euryarchaeota	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1upmm__d2v67p___1	Viridiplantae	Viridiplantae	Streptophyta	Chlorophyta	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1upna__d1fod1___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	icosahedral viral capsid [GO:0019030]; structural molecule activity [GO:0005198]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	icosahedral viral capsid [GO:0019030]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1upnc__d4cdub___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1uppc1_d1rcoh2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1uppg1_d1iwai2__1	Viridiplantae		Streptophyta	Rhodophyta	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		chloroplast [GO:0009507]	chloroplast [GO:0009507]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	
d1upra__d2coaa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein kinase C binding [GO:0005080]; protein serine/threonine kinase activity [GO:0004674]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell death [GO:0008219]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; endothelial tube morphogenesis [GO:0061154]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; protein kinase D signaling [GO:0089700]; protein phosphorylation [GO:0006468]; sphingolipid biosynthetic process [GO:0030148]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]	adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell death [GO:0008219]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; endothelial tube morphogenesis [GO:0061154]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; protein kinase D signaling [GO:0089700]; protein phosphorylation [GO:0006468]; sphingolipid biosynthetic process [GO:0030148]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cytoplasm [GO:0005737]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein kinase C binding [GO:0005080]; protein serine/threonine kinase activity [GO:0004674]
d1upra__d2dlwa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]	cytosol [GO:0005829]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; leukocyte migration [GO:0050900]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165]	phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; leukocyte migration [GO:0050900]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]	transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]
d1upsa1_d2a6va1__1		Fungi	Firmicutes	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]		COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1upsb1_d2dwra___1			Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; receptor-mediated virion attachment to host cell [GO:0046813]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; receptor-mediated virion attachment to host cell [GO:0046813]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]		host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	
d1upsb1_d3azya___1			Firmicutes	Thermotogae	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1uq4a__d3hiqb1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1uqsa2_d1k8da2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1uqxa__d4aocb___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1uqxa__d5a3ob___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]		single-species biofilm formation [GO:0044010]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1uqza1_d3rild2__1		Metazoa	Proteobacteria	Chordata	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	xylan catabolic process [GO:0045493]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	endo-1,4-beta-xylanase activity [GO:0031176]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1ur4b__d4c7db2__1			Firmicutes	Actinobacteria	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]			arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]	beta-N-acetylhexosaminidase activity [GO:0004563]
d1ur5a2_d4tvob2__1			Chloroflexi	Actinobacteria	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	L-malate dehydrogenase activity [GO:0030060]	L-malate dehydrogenase activity [GO:0030060]
d1ur6a__d3w31b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; UBC13-MMS2 complex [GO:0031372]; UBC13-UEV1A complex [GO:0035370]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; activation of MAPK activity [GO:0000187]; cellular protein modification process [GO:0006464]; DNA double-strand break processing [GO:0000729]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone ubiquitination [GO:0016574]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of DNA repair [GO:0045739]; positive regulation of histone modification [GO:0031058]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of DNA repair [GO:0006282]; regulation of histone ubiquitination [GO:0033182]; T cell receptor signaling pathway [GO:0050852]	cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; cellular protein modification process [GO:0006464]; DNA double-strand break processing [GO:0000729]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone ubiquitination [GO:0016574]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of DNA repair [GO:0045739]; positive regulation of histone modification [GO:0031058]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of DNA repair [GO:0006282]; regulation of histone ubiquitination [GO:0033182]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; UBC13-MMS2 complex [GO:0031372]; UBC13-UEV1A complex [GO:0035370]; ubiquitin ligase complex [GO:0000151]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]
d1ur9a3_d2b2pa2__1			Proteobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	
d1urcb1_d3my1b1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d1urcd2_d4yoza1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; transcription factor complex [GO:0005667]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription factor binding [GO:0008134]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of cellular senescence [GO:2000773]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell division [GO:0051302]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of cellular senescence [GO:2000773]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell division [GO:0051302]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	promoter-specific chromatin binding [GO:1990841]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription factor binding [GO:0008134]
d1urga__d3fgsa___1		Metazoa	Firmicutes	Chordata	plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]		actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	carbohydrate transmembrane transporter activity [GO:0015144]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d1urha1_d2oraa1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; 3-mercaptopyruvate sulfurtransferase activity [GO:0016784]; thiosulfate sulfurtransferase activity [GO:0004792]; DNA protection [GO:0042262]; response to antibiotic [GO:0046677]; response to oxidative stress [GO:0006979]; transsulfuration [GO:0019346]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5S rRNA binding [GO:0008097]; thiosulfate sulfurtransferase activity [GO:0004792]; rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; transsulfuration [GO:0019346]	DNA protection [GO:0042262]; response to antibiotic [GO:0046677]; response to oxidative stress [GO:0006979]; transsulfuration [GO:0019346]	rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; transsulfuration [GO:0019346]	cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	3-mercaptopyruvate sulfurtransferase activity [GO:0016784]; thiosulfate sulfurtransferase activity [GO:0004792]	5S rRNA binding [GO:0008097]; thiosulfate sulfurtransferase activity [GO:0004792]
d1uria__d5u7nh___1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]			periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1urib__d1ilug___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1urla__d1beyh1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	carbohydrate binding [GO:0030246]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1urma1_d5echf1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1urra__d4ojgb___1	Metazoa		Arthropoda	Crenarchaeota	cytoplasm [GO:0005737]; acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]; cellular metabolic process [GO:0044237]	acylphosphatase activity [GO:0003998]	cellular metabolic process [GO:0044237]		cytoplasm [GO:0005737]		acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	acylphosphatase activity [GO:0003998]
d1ursb__d3seua1__1			Firmicutes	Proteobacteria	plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	plasma membrane [GO:0005886]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	carbohydrate transmembrane transporter activity [GO:0015144]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1urva__d1ngkh___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]; fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cytosol [GO:0005829]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1urxa__d1qf3a___1		Viridiplantae	Bacteroidetes	Streptophyta	extracellular region [GO:0005576]; beta-agarase activity [GO:0033916]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		beta-agarase activity [GO:0033916]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1urya__d2uumg___1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]; fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytosol [GO:0005829]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	phycobilisome [GO:0030089]	catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	
d1urzd1_d1uh2a1__1				Firmicutes	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1us2a2_d2gvyb2__1		Fungi	Proteobacteria	Ascomycota	cell outer membrane [GO:0009279]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	xylan catabolic process [GO:0045493]	carbohydrate catabolic process [GO:0016052]	cell outer membrane [GO:0009279]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]	endo-1,4-beta-xylanase activity [GO:0031176]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1us5a__d4gvoa___1			Deinococcus-Thermus	Firmicutes								
d1us6b__d1rfya___1			Proteobacteria	Proteobacteria	conjugation [GO:0000746]; negative regulation of transcription, DNA-templated [GO:0045892]	conjugation [GO:0000746]; negative regulation of transcription, DNA-templated [GO:0045892]	conjugation [GO:0000746]; negative regulation of transcription, DNA-templated [GO:0045892]	conjugation [GO:0000746]; negative regulation of transcription, DNA-templated [GO:0045892]				
d1usba1_d2hqtl___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]; enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]; positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]
d1usbb1_d5ecoc2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1usfb__d5bnca___1			Deinococcus-Thermus	Actinobacteria	FMN binding [GO:0010181]	cofactor binding [GO:0048037]					FMN binding [GO:0010181]	cofactor binding [GO:0048037]
d1usia__d4rxmb___1			Proteobacteria		outer membrane-bounded periplasmic space [GO:0030288]; leucine binding [GO:0070728]; leucine transport [GO:0015820]		leucine transport [GO:0015820]		outer membrane-bounded periplasmic space [GO:0030288]		leucine binding [GO:0070728]	
d1usla__d4lfnb___1			Actinobacteria		extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]		ribose-5-phosphate isomerase activity [GO:0004751]	
d1usna__d1s0ea3__1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	negative regulation of neurotransmitter secretion [GO:0046929]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1uswa__d4s0xa___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]; cell wall macromolecule catabolic process [GO:0016998]; cellulose catabolic process [GO:0030245]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cellulose catabolic process [GO:0030245]; cell wall macromolecule catabolic process [GO:0016998]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]		cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]	triglyceride lipase activity [GO:0004806]
d1usxc__d4wa3a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1usyc__d1wqwa2__1			Thermotogae	Euryarchaeota	cytoplasm [GO:0005737]; histidine-tRNA ligase activity [GO:0004821]; histidine biosynthetic process [GO:0000105]; histidyl-tRNA aminoacylation [GO:0006427]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	histidine biosynthetic process [GO:0000105]; histidyl-tRNA aminoacylation [GO:0006427]	cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]		histidine-tRNA ligase activity [GO:0004821]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d1ut1e__d1ut2e___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]	pilus [GO:0009289]			pilus [GO:0009289]	pilus [GO:0009289]		
d1ut1e__d3rfzd2__1			Proteobacteria	Proteobacteria	pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d1ut2g__d4xocb___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]	pilus [GO:0009289]; cell adhesion [GO:0007155]		cell adhesion [GO:0007155]	pilus [GO:0009289]	pilus [GO:0009289]		
d1ut2h__d5wtab2__1			Proteobacteria	Firmicutes	pilus [GO:0009289]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	pilus [GO:0009289]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]		
d1utaa__d1x60a___1			Proteobacteria	Firmicutes	cell division site [GO:0032153]; cell septum [GO:0030428]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; peptidoglycan binding [GO:0042834]; cell division [GO:0051301]; cytokinetic process [GO:0032506]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]	cell wall [GO:0005618]; extracellular region [GO:0005576]; outer membrane-bounded periplasmic space [GO:0030288]; metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; cell wall organization [GO:0071555]; establishment of competence for transformation [GO:0030420]; peptidoglycan catabolic process [GO:0009253]; sporulation resulting in formation of a cellular spore [GO:0030435]	cell division [GO:0051301]; cytokinetic process [GO:0032506]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]	cell wall organization [GO:0071555]; establishment of competence for transformation [GO:0030420]; peptidoglycan catabolic process [GO:0009253]; sporulation resulting in formation of a cellular spore [GO:0030435]	cell division site [GO:0032153]; cell septum [GO:0030428]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; extracellular region [GO:0005576]; outer membrane-bounded periplasmic space [GO:0030288]	peptidoglycan binding [GO:0042834]	metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]
d1utdj__d3zzla___1			Firmicutes	Firmicutes	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d1utfb__d3ztes___1				Firmicutes		RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]		DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]				RNA binding [GO:0003723]
d1utfu__d3zter___1				Firmicutes		RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]		DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]				RNA binding [GO:0003723]
d1utha1_d1ce2a2__1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	extracellular space [GO:0005615]; specific granule [GO:0042581]; iron ion binding [GO:0005506]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]		antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]		extracellular space [GO:0005615]; specific granule [GO:0042581]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	iron ion binding [GO:0005506]; serine-type endopeptidase activity [GO:0004252]
d1utha1_d3ttma___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	periplasmic space [GO:0042597]; putrescine binding [GO:0019810]; polyamine transport [GO:0015846]		polyamine transport [GO:0015846]		periplasmic space [GO:0042597]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	putrescine binding [GO:0019810]
d1utja__d3e1xb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; sodium channel regulator activity [GO:0017080]; cornification [GO:0070268]; positive regulation of sodium ion transport [GO:0010765]	digestion [GO:0007586]	cornification [GO:0070268]; positive regulation of sodium ion transport [GO:0010765]	extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; sodium channel regulator activity [GO:0017080]
d1utlm__d3kqea___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1utoa__d1ad8.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d1utqa__d1nu7.2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d1utrb__d2utgb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; nuclear envelope [GO:0005635]; rough endoplasmic reticulum [GO:0005791]; secretory granule [GO:0030141]; phospholipase A2 inhibitor activity [GO:0019834]; polychlorinated biphenyl binding [GO:0097160]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-13 production [GO:0032696]; negative regulation of interleukin-4 production [GO:0032713]; negative regulation of interleukin-5 production [GO:0032714]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of inflammatory response [GO:0050727]; regulation of mRNA stability [GO:0043488]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to fibroblast growth factor [GO:0071774]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to organic substance [GO:0010033]; response to ozone [GO:0010193]; response to silicon dioxide [GO:0034021]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; phospholipase A2 inhibitor activity [GO:0019834]; steroid binding [GO:0005496]; signal transduction [GO:0007165]	negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-13 production [GO:0032696]; negative regulation of interleukin-4 production [GO:0032713]; negative regulation of interleukin-5 production [GO:0032714]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of inflammatory response [GO:0050727]; regulation of mRNA stability [GO:0043488]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to fibroblast growth factor [GO:0071774]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to organic substance [GO:0010033]; response to ozone [GO:0010193]; response to silicon dioxide [GO:0034021]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]	signal transduction [GO:0007165]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; nuclear envelope [GO:0005635]; rough endoplasmic reticulum [GO:0005791]; secretory granule [GO:0030141]	extracellular region [GO:0005576]	phospholipase A2 inhibitor activity [GO:0019834]; polychlorinated biphenyl binding [GO:0097160]	phospholipase A2 inhibitor activity [GO:0019834]; steroid binding [GO:0005496]
d1utta__d2c6fa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; bradykinin receptor binding [GO:0031711]; carboxypeptidase activity [GO:0004180]; chloride ion binding [GO:0031404]; dipeptidyl-peptidase activity [GO:0008239]; drug binding [GO:0008144]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallodipeptidase activity [GO:0070573]; metallopeptidase activity [GO:0008237]; mitogen-activated protein kinase binding [GO:0051019]; mitogen-activated protein kinase kinase binding [GO:0031434]; peptidyl-dipeptidase activity [GO:0008241]; tripeptidyl-peptidase activity [GO:0008240]; zinc ion binding [GO:0008270]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of blood pressure [GO:0045777]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; posttranscriptional regulation of gene expression [GO:0010608]; proteolysis [GO:0006508]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of blood vessel diameter [GO:0097746]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; spermatogenesis [GO:0007283]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of blood pressure [GO:0045777]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; posttranscriptional regulation of gene expression [GO:0010608]; proteolysis [GO:0006508]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of blood vessel diameter [GO:0097746]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; bradykinin receptor binding [GO:0031711]; carboxypeptidase activity [GO:0004180]; chloride ion binding [GO:0031404]; dipeptidyl-peptidase activity [GO:0008239]; drug binding [GO:0008144]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallodipeptidase activity [GO:0070573]; metallopeptidase activity [GO:0008237]; mitogen-activated protein kinase binding [GO:0051019]; mitogen-activated protein kinase kinase binding [GO:0031434]; peptidyl-dipeptidase activity [GO:0008241]; tripeptidyl-peptidase activity [GO:0008240]; zinc ion binding [GO:0008270]
d1utvj__d3ztej___1				Firmicutes		RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]		DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]				RNA binding [GO:0003723]
d1utwa1_d4udjf___1												
d1utwa2_d5ewsf___1		Metazoa		Chordata		carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]						carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d1utwb1_d2exic2__1				Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1utwd1_d3byka___1				Firmicutes		extracellular region [GO:0005576]; levansucrase activity [GO:0050053]; carbohydrate utilization [GO:0009758]		carbohydrate utilization [GO:0009758]		extracellular region [GO:0005576]		levansucrase activity [GO:0050053]
d1utwf1_d3om6d___1				Firmicutes		levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]		carbohydrate utilization [GO:0009758]				levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]
d1utwf2_d1q8vb___1		Viridiplantae		Streptophyta		carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]						carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1utxa__d3scgc1__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]			DNA binding [GO:0003677]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d1utzb__d3eima___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1uu0a__d1amsa___1			Thermotogae	Proteobacteria	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	histidine biosynthetic process [GO:0000105]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1uu0b__d5lucb___1		Metazoa	Thermotogae	Chordata	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]; cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]	histidine biosynthetic process [GO:0000105]	cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]		cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]	alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]
d1uu0c__d1aria___1			Thermotogae	Proteobacteria	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	histidine biosynthetic process [GO:0000105]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1uu2b__d1pg8b___1			Thermotogae	Proteobacteria	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	histidine biosynthetic process [GO:0000105]	transsulfuration [GO:0019346]			histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d1uuga__d1l9ga___1			Proteobacteria	Thermotogae	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; uracil DNA N-glycosylase activity [GO:0004844]; DNA repair [GO:0006281]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	DNA repair [GO:0006281]	mitochondrion [GO:0005739]; nucleus [GO:0005634]		uracil DNA N-glycosylase activity [GO:0004844]	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; uracil DNA N-glycosylase activity [GO:0004844]
d1uugc__d3wdfb___1			Proteobacteria	Firmicutes	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	cytoplasm [GO:0005737]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d1uugc__d4euga___1			Proteobacteria	Proteobacteria	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d1uulb__d4hi7a1__1		Metazoa		Arthropoda								
d1uule__d4dejd1__1				Proteobacteria		transferase activity [GO:0016740]						transferase activity [GO:0016740]
d1uulg__d4mf7a1__1				Proteobacteria		transferase activity [GO:0016740]						transferase activity [GO:0016740]
d1uulh__d2vd0d2__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1uupa1_d1qb5d___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1uupa2_d3mc0b2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d1uupc1_d1ltad___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]		killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1uupd1_d1ha5a1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1uuqa__d2x1ia___1			Proteobacteria	Deinococcus-Thermus	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]
d1uuta__d1z1db2__1					ATP binding [GO:0005524]; metal ion binding [GO:0046872]; DNA replication [GO:0006260]; viral genome replication [GO:0019079]	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]; viral genome replication [GO:0019079]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]		host cell nucleus [GO:0042025]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]
d1uuva1_d1riea___1		Metazoa	Proteobacteria	Chordata	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	aromatic compound catabolic process [GO:0019439]			integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	dioxygenase activity [GO:0051213]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d1uuva2_d2xr8i2__1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			dioxygenase activity [GO:0051213]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1uuwb__d2yfjb___1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			dioxygenase activity [GO:0051213]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1uuxa__d3mcia___1	Viridiplantae		Streptophyta	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; auxin-activated signaling pathway [GO:0009734]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; response to metal ion [GO:0010038]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	auxin-activated signaling pathway [GO:0009734]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; response to metal ion [GO:0010038]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]	
d1uuxa__d5erqa2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; auxin-activated signaling pathway [GO:0009734]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; response to metal ion [GO:0010038]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	auxin-activated signaling pathway [GO:0009734]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; response to metal ion [GO:0010038]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]	ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]
d1uv4a1_d5ayef___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	arabinan catabolic process [GO:0031222]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]		arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]	transferase activity, transferring glycosyl groups [GO:0016757]
d1uv6e__d3sh1f1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d1uv6f__d2ymdc___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d1uv6j__d4xk9b1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d1uvca__d1fk5a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid transport [GO:0006869]	lipid transport [GO:0006869]			lipid binding [GO:0008289]	lipid binding [GO:0008289]
d1uvcb__d1psya___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lipid binding [GO:0008289]; lipid transport [GO:0006869]	nutrient reservoir activity [GO:0045735]	lipid transport [GO:0006869]				lipid binding [GO:0008289]	nutrient reservoir activity [GO:0045735]
d1uvdf__d2j4kd___1				Crenarchaeota		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; UMP kinase activity [GO:0033862]; 'de novo' CTP biosynthetic process [GO:0044210]; UDP biosynthetic process [GO:0006225]		'de novo' CTP biosynthetic process [GO:0044210]; UDP biosynthetic process [GO:0006225]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; UMP kinase activity [GO:0033862]
d1uvdg__d3c20b1__1				Euryarchaeota		cytosol [GO:0005829]; aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]; homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]		homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]		cytosol [GO:0005829]		aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]
d1uvhb__d2jd6d___1			Actinobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d1uvhd__d2jd7d___1			Actinobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d1uvoa__d1aq7a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1uvpa__d3h7oa___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	serine-type endopeptidase activity [GO:0004252]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1uvqa1_d1dbmh2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; interferon-gamma-mediated signaling pathway [GO:0060333]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; interferon-gamma-mediated signaling pathway [GO:0060333]; T cell receptor signaling pathway [GO:0050852]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1uvqa1_d1op3k1__1	Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; interferon-gamma-mediated signaling pathway [GO:0060333]; T cell receptor signaling pathway [GO:0050852]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; interferon-gamma-mediated signaling pathway [GO:0060333]; T cell receptor signaling pathway [GO:0050852]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]	
d1uvt.1_d3sn8a___1	Metazoa		Chordata		extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1uvva__d4ndra___1				Proteobacteria		cytoplasm [GO:0005737]; molybdenum ion binding [GO:0030151]; nutrient reservoir activity [GO:0045735]				cytoplasm [GO:0005737]		molybdenum ion binding [GO:0030151]; nutrient reservoir activity [GO:0045735]
d1uvya__d5v3ub___1			Ciliophora	Firmicutes	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen transport [GO:0015671]		oxygen transport [GO:0015671]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d1uw4d__d1h2tc2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; exon-exon junction complex [GO:0035145]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]; animal organ regeneration [GO:0031100]; liver development [GO:0001889]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	animal organ regeneration [GO:0031100]; liver development [GO:0001889]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; exon-exon junction complex [GO:0035145]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]	RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]	mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]
d1uw6e__d5lxbh___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d1uw6k__d2xyte___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d1uw6k__d3sq9d___1	Metazoa		Mollusca		cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]				cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]		extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	
d1uw6o__d2c9ti___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d1uw6r__d3wtob1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d1uw7a1_d2j98b___1					cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1uwai__d2v67j___1	Viridiplantae	Viridiplantae	Chlorophyta	Chlorophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1uwaj__d1burs___1	Viridiplantae		Chlorophyta		chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]		magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	
d1uwaw__d3axkt___1	Viridiplantae	Viridiplantae	Chlorophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1uwca1_d1dt3a___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]; cell wall macromolecule catabolic process [GO:0016998]; cellulose catabolic process [GO:0030245]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cellulose catabolic process [GO:0030245]; cell wall macromolecule catabolic process [GO:0016998]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]		cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]	triglyceride lipase activity [GO:0004806]
d1uwel1_d1mlba1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1uwel2_d4nqta2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1uwex1_d4y4fb___1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1uwex2_d2i60l2__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1uwey2_d2g9hb1__1		Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1uwey2_d2wzpf1__1						virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		virus tail, baseplate [GO:0098025]		
d1uwgl2_d3mlym1__1												
d1uwgx1_d1igjb2__1												
d1uwgx2_d4toyl1__1												
d1uwgy1_d4uujb1__1				Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1uwia1_d1uqza1__1			Crenarchaeota	Proteobacteria	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]			beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]	endo-1,4-beta-xylanase activity [GO:0031176]
d1uwic__d1bgmk5__1			Crenarchaeota		beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]	
d1uwic__d1e4ia___1			Crenarchaeota	Firmicutes	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]			beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1uwma__d1n63a2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1uwoa__d2ix7a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]
d1uwob__d4cfra___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell leading edge [GO:0031252]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin-dependent ATPase activity [GO:0030898]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]; actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell leading edge [GO:0031252]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; actin-dependent ATPase activity [GO:0030898]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]
d1uwra__d5dt7c___1			Crenarchaeota	Firmicutes	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]			beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1uwza__d4wifb___1			Firmicutes	Actinobacteria	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; pyrimidine nucleobase salvage [GO:0043100]; uridine biosynthetic process [GO:0046109]	cytidine deamination [GO:0009972]	cytidine deamination [GO:0009972]; pyrimidine nucleobase salvage [GO:0043100]; uridine biosynthetic process [GO:0046109]	cytosol [GO:0005829]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; zinc ion binding [GO:0008270]
d1uwzb__d2z3ha___1		Fungi	Firmicutes	Ascomycota	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cytidine deamination [GO:0009972]	response to antibiotic [GO:0046677]	cytosol [GO:0005829]		cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d1uwzb__d4f3wa___1			Firmicutes	Actinobacteria	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	cytidine deamination [GO:0009972]		cytosol [GO:0005829]		cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1ux0a__d2z3ic___1		Fungi	Firmicutes	Ascomycota	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cytidine deamination [GO:0009972]	response to antibiotic [GO:0046677]	cytosol [GO:0005829]		cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d1ux1b__d1m9nb2__1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	cytidine deamination [GO:0009972]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]	cytosol [GO:0005829]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1ux1d__d5k82b___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; innate immune response [GO:0045087]	cytidine deamination [GO:0009972]	base conversion or substitution editing [GO:0016553]; innate immune response [GO:0045087]	cytosol [GO:0005829]		cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]
d1ux2b__d3t4mi1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d1ux2c__d5afjb___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d1ux2e__d5afma___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d1ux2f__d5afmd___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d1ux2h__d5afmb___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d1ux2i__d2xnvb___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d1ux7a__d3zyhb___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	xylan catabolic process [GO:0045493]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	alpha-L-arabinofuranosidase activity [GO:0046556]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1ux9a__d4yu4a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]; fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	hemoglobin complex [GO:0005833]	catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1uxaa__d3u6xb2__1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]	metal ion binding [GO:0046872]	
d1uxab__d1kkeb2__1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral outer capsid [GO:0039624]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	viral outer capsid [GO:0039624]	metal ion binding [GO:0046872]	
d1uxba__d2f0ca1__1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]	metal ion binding [GO:0046872]	
d1uxea__d2oj5d1__1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral outer capsid [GO:0039624]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	viral outer capsid [GO:0039624]	metal ion binding [GO:0046872]	
d1uxeb__d3f0yh___1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	viral capsid [GO:0019028]	metal ion binding [GO:0046872]	
d1uxec__d3bq4f___1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	viral capsid [GO:0019028]	metal ion binding [GO:0046872]	
d1uxga2_d1ie3a2__1			Chloroflexi	Proteobacteria	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	L-malate dehydrogenase activity [GO:0030060]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]
d1uxha1_d1i10b1__1		Metazoa	Chloroflexi	Chordata	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-malate dehydrogenase activity [GO:0030060]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1uxha2_d2e37c2__1			Chloroflexi	Deinococcus-Thermus	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d1uxhb2_d5es3c2__1		Metazoa	Chloroflexi	Chordata	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1uxib2_d3pqda2__1			Chloroflexi	Firmicutes	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d1uxkc2_d4a73a2__1			Chloroflexi	Deinococcus-Thermus	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d1uxmb__d3km2w___1	Metazoa	Viridiplantae	Chordata	Streptophyta	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	chloroplast [GO:0009507]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	removal of superoxide radicals [GO:0019430]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chloroplast [GO:0009507]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]
d1uxme__d3gqfb___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1uxmg__d1hl4a___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d1uxna__d3jz4b___1			Crenarchaeota	Proteobacteria	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	cytoplasm [GO:0005737]; NADP binding [GO:0050661]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; gamma-aminobutyric acid catabolic process [GO:0009450]; nitrogen compound metabolic process [GO:0006807]		gamma-aminobutyric acid catabolic process [GO:0009450]; nitrogen compound metabolic process [GO:0006807]		cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	NADP binding [GO:0050661]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]
d1uxra__d4zulb___1		Metazoa	Crenarchaeota	Chordata	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]; cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]		cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]
d1uxsa1_d4b5ea___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1uxsa2_d1rk0a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1uxta__d2id2c___1			Crenarchaeota	Firmicutes	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]					glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]
d1uxta__d5n5sc___1		Viridiplantae	Crenarchaeota	Streptophyta	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	lactaldehyde dehydrogenase activity [GO:0008911]					glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	lactaldehyde dehydrogenase activity [GO:0008911]
d1uxwa1_d3fb6b2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1uxwa1_d3t0va___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1uxwb1_d1t5wd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1uxya2_d3tx1a2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; UDP-N-acetylmuramate dehydrogenase activity [GO:0008762]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; UDP-N-acetylmuramate dehydrogenase activity [GO:0008762]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; UDP-N-acetylmuramate dehydrogenase activity [GO:0008762]	FAD binding [GO:0071949]; UDP-N-acetylmuramate dehydrogenase activity [GO:0008762]
d1uxza__d2b9vm1__1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	carbohydrate metabolic process [GO:0005975]				carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d1uy0a__d1ciya1__1			Proteobacteria	Firmicutes	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	carbohydrate metabolic process [GO:0005975]	sporulation resulting in formation of a cellular spore [GO:0030435]			carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d1uy0b__d5ofie___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]				carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1uy1a__d1uyzb___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1uy1a__d3dypa1__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1uy3a__d1uyxb___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1uy4a__d3leia___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; cholesterol binding [GO:0015485]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; hemolysis in other organism [GO:0044179]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	hemolysis in other organism [GO:0044179]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]	cholesterol binding [GO:0015485]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1uy8a__d2qf6a___1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1uyca__d2ccua___1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1uyda__d5d7ca___1	Metazoa		Chordata	Firmicutes	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d1uyea__d3r4ma___1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1uyka__d1b62a2__1	Metazoa		Chordata	Proteobacteria	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	mismatch repair complex [GO:0032300]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	mismatch repair complex [GO:0032300]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]
d1uypa1_d3pvon___1		Metazoa	Thermotogae	Chordata	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	carbohydrate metabolic process [GO:0005975]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	beta-fructofuranosidase activity [GO:0004564]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1uypb2_d5ayee___1			Thermotogae	Firmicutes	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]			beta-fructofuranosidase activity [GO:0004564]	transferase activity, transferring glycosyl groups [GO:0016757]
d1uypc2_d3c2ud1__1			Thermotogae	Firmicutes	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			beta-fructofuranosidase activity [GO:0004564]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1uype1_d2dvdc___1		Viridiplantae	Thermotogae	Streptophyta	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]				beta-fructofuranosidase activity [GO:0004564]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1uypf1_d4celb___1		Fungi	Thermotogae	Ascomycota	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	beta-fructofuranosidase activity [GO:0004564]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d1uyqa1_d1qoxj___1			Firmicutes	Firmicutes	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1uyra1_d2vx2f___1	Fungi	Metazoa	Ascomycota	Chordata	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	mitochondrion [GO:0005739]; catalytic activity [GO:0003824]; fatty acid metabolic process [GO:0006631]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	fatty acid metabolic process [GO:0006631]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	catalytic activity [GO:0003824]
d1uyub__d4h24d___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d1uywl2_d5cexc1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1uywn1_d4huwb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1uywn2_d2o5zl2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1uyxa__d3mv021__1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1uyxb__d1jz4d3__1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1uyza__d3t2ob1__1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1uyzb__d5ifta5__1		Fungi	Proteobacteria	Ascomycota	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]; carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]
d1uz2x__d1s2pa___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	extracellular space [GO:0005615]; pigment binding [GO:0031409]			extracellular region [GO:0005576]	extracellular space [GO:0005615]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	pigment binding [GO:0031409]
d1uz2x__d4nnsa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]		brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1uz4a__d1w91b2__1			Proteobacteria	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d1uz6e1_d4x4zb___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1uz6h1_d2dqfd___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1uz6l1_d5m30e1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1uz6m1_d1nbzb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1uz6v1_d2visa1__1	Metazoa		Chordata	Negarnaviricota	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	host cell surface receptor binding [GO:0046789]
d1uz6w1_d1efxe2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1uz8a1_d2rq8a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1uz8a2_d2oz4a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1uz8a2_d3quzb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1uzba__d1o00g___1		Metazoa	Deinococcus-Thermus	Chordata	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d1uzba__d3k2wc1__1			Deinococcus-Thermus	Proteobacteria	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	betaine-aldehyde dehydrogenase activity [GO:0008802]					oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	betaine-aldehyde dehydrogenase activity [GO:0008802]
d1uzhf__d1upmt___1	Viridiplantae	Viridiplantae	Chlorophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1uzhm__d2v6ai___1	Viridiplantae	Viridiplantae	Chlorophyta	Chlorophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1uzna__d1up6b1__1			Actinobacteria	Thermotogae	plasma membrane [GO:0005886]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; acetoacetyl-CoA reductase activity [GO:0018454]; NADPH binding [GO:0070402]; mycolic acid biosynthetic process [GO:0071768]; oxidation-reduction process [GO:0055114]; short-chain fatty acid metabolic process [GO:0046459]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]	mycolic acid biosynthetic process [GO:0071768]; oxidation-reduction process [GO:0055114]; short-chain fatty acid metabolic process [GO:0046459]	carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]		3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; acetoacetyl-CoA reductase activity [GO:0018454]; NADPH binding [GO:0070402]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d1uzna__d3ufxf1__1			Actinobacteria	Deinococcus-Thermus	plasma membrane [GO:0005886]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; acetoacetyl-CoA reductase activity [GO:0018454]; NADPH binding [GO:0070402]; mycolic acid biosynthetic process [GO:0071768]; oxidation-reduction process [GO:0055114]; short-chain fatty acid metabolic process [GO:0046459]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; tricarboxylic acid cycle [GO:0006099]	mycolic acid biosynthetic process [GO:0071768]; oxidation-reduction process [GO:0055114]; short-chain fatty acid metabolic process [GO:0046459]	tricarboxylic acid cycle [GO:0006099]	plasma membrane [GO:0005886]		3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; acetoacetyl-CoA reductase activity [GO:0018454]; NADPH binding [GO:0070402]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]
d1uzrb__d1mhzd___1			Actinobacteria	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	methane monooxygenase activity [GO:0015049]; methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	ribonucleoside-diphosphate reductase complex [GO:0005971]		metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	methane monooxygenase activity [GO:0015049]
d1uzvb__d2vnvd___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1uzvd__d5a6yd___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1uzya__d3l2yb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1uzyb__d1dgla___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1uzyb__d5t9xb___1	Viridiplantae		Streptophyta	Bacteroidetes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	beta-agarase activity [GO:0033916]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	beta-agarase activity [GO:0033916]
d1v00c__d2e7qd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1v00d__d2e7ta___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1v00d__d4no4e___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of viral entry into host cell [GO:0046598]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of viral entry into host cell [GO:0046598]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]
d1v02b__d1p6wa2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular space [GO:0005615]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1v05a__d1lyqb___1	Metazoa		Chordata	Proteobacteria	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]	periplasmic space [GO:0042597]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]	copper ion binding [GO:0005507]
d1v07a__d4f6ga___1	Metazoa	Metazoa	Nemertea (ribbon worms)	Nemertea (ribbon worms)	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1v07a__d4hrrf___1	Metazoa	Metazoa	Nemertea (ribbon worms)	Mollusca	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1v08a__d1tr1c___1	Viridiplantae		Streptophyta	Firmicutes	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	cellulose catabolic process [GO:0030245]	chloroplast [GO:0009507]		beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1v0ea2_d4hiza2__1					virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	metabolic process [GO:0008152]	virus tail, fiber [GO:0098024]		endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; metal ion binding [GO:0046872]
d1v0ee1_d1w21a___1				Negarnaviricota	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	virus tail, fiber [GO:0098024]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1v0ef1_d1ms3a2__1					virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	pathogenesis [GO:0009405]	virus tail, fiber [GO:0098024]		endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]	exo-alpha-sialidase activity [GO:0004308]
d1v0fa1_d4mwla___1				Negarnaviricota	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	virus tail, fiber [GO:0098024]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1v0fb1_d3nn9a___1				Negarnaviricota	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	virus tail, fiber [GO:0098024]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1v0fd2_d4hizb2__1					virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	metabolic process [GO:0008152]	virus tail, fiber [GO:0098024]		endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; metal ion binding [GO:0046872]
d1v0fe2_d2yvva1__1				Firmicutes	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	hyalurononglucosaminidase activity [GO:0004415]; capsule polysaccharide biosynthetic process [GO:0045227]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	capsule polysaccharide biosynthetic process [GO:0045227]	virus tail, fiber [GO:0098024]		endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]	hyalurononglucosaminidase activity [GO:0004415]
d1v0hx1_d4jqka___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]	integral component of membrane [GO:0016021]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1v0ka__d1vfkb5__1			Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	
d1v0ka__d3mv033__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1v0la__d1pj9a4__1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1v0za__d2aepa1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	adaptive immune response [GO:0002250]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	
d1v0zc__d5b2cb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]
d1v0zd__d4mzab___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]
d1v10a1_d1e5yc___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1v10a3_d2ppec1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1v10a3_d3sbrh2__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]		copper ion import [GO:0015677]; denitrification pathway [GO:0019333]		membrane [GO:0016020]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d1v11b2_d3dv0d2__1	Metazoa		Chordata	Firmicutes	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]		3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1v13b__d2gzjf___1			Proteobacteria	Proteobacteria	extrachromosomal circular DNA [GO:0005727]; protein-containing complex [GO:0032991]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; pathogenesis [GO:0009405]	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; pathogenesis [GO:0009405]	bacteriocin immunity [GO:0030153]	extrachromosomal circular DNA [GO:0005727]; protein-containing complex [GO:0032991]	protein-containing complex [GO:0032991]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]	protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]
d1v14b__d2ivkc___1			Proteobacteria	Proteobacteria	extrachromosomal circular DNA [GO:0005727]; protein-containing complex [GO:0032991]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; pathogenesis [GO:0009405]	endonuclease activity [GO:0004519]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; pathogenesis [GO:0009405]		extrachromosomal circular DNA [GO:0005727]; protein-containing complex [GO:0032991]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]	endonuclease activity [GO:0004519]
d1v15d__d1emvb1__1			Proteobacteria	Proteobacteria	extrachromosomal circular DNA [GO:0005727]; protein-containing complex [GO:0032991]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; pathogenesis [GO:0009405]	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; pathogenesis [GO:0009405]	bacteriocin immunity [GO:0030153]	extrachromosomal circular DNA [GO:0005727]; protein-containing complex [GO:0032991]	protein-containing complex [GO:0032991]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]	protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]
d1v16b2_d2g67a3__1	Metazoa		Chordata	Proteobacteria	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	cytosol [GO:0005829]; membrane [GO:0016020]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]
d1v1ba__d3b1rd___1			Deinococcus-Thermus	Proteobacteria	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]; phosphorylation [GO:0016310]	kinase activity [GO:0016301]; nucleotide binding [GO:0000166]; phosphotransferase activity, alcohol group as acceptor [GO:0016773]	phosphorylation [GO:0016310]				2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]	kinase activity [GO:0016301]; nucleotide binding [GO:0000166]; phosphotransferase activity, alcohol group as acceptor [GO:0016773]
d1v1bc__d3rs9a2__1			Deinococcus-Thermus	Thermotogae	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]; phosphorylation [GO:0016310]	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]; nicotinamide nucleotide metabolic process [GO:0046496]	phosphorylation [GO:0016310]	nicotinamide nucleotide metabolic process [GO:0046496]			2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]
d1v1ga__d3tuyf___1	Viridiplantae	Metazoa	Streptophyta	Mollusca	calcineurin complex [GO:0005955]; cell [GO:0005623]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; cellular potassium ion homeostasis [GO:0030007]; detection of calcium ion [GO:0005513]; hypotonic salinity response [GO:0042539]	myosin complex [GO:0016459]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	cellular potassium ion homeostasis [GO:0030007]; detection of calcium ion [GO:0005513]; hypotonic salinity response [GO:0042539]		calcineurin complex [GO:0005955]; cell [GO:0005623]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	myosin complex [GO:0016459]	calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calcium ion binding [GO:0005509]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]
d1v1jf__d4rhcd___1			Actinobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1v1ji__d4rhcc___1			Actinobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1v1jl__d5ydba___1			Actinobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d1v1mb2_d1tkba3__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	pentose-phosphate shunt [GO:0006098]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1v1oa1_d1aw7a1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		toxin activity [GO:0090729]
d1v1ob2_d4rgma2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1v1pa2_d4dxfa2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1v1sb__d2i6ab___1		Metazoa	Deinococcus-Thermus	Chordata	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]; phosphorylation [GO:0016310]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; AMP salvage [GO:0044209]; dATP biosynthetic process [GO:0006175]; purine ribonucleoside salvage [GO:0006166]; purine-containing compound salvage [GO:0043101]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	phosphorylation [GO:0016310]	AMP salvage [GO:0044209]; dATP biosynthetic process [GO:0006175]; purine-containing compound salvage [GO:0043101]; purine ribonucleoside salvage [GO:0006166]; ribonucleoside monophosphate biosynthetic process [GO:0009156]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]	adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d1v1ta1_d1w9ea2__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]; actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]; actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]	cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]	cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]
d1v1tb1_d1k32e1__1	Metazoa		Chordata	Euryarchaeota	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]; actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	proteolysis [GO:0006508]	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]	cytoplasm [GO:0005737]	cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]	serine-type peptidase activity [GO:0008236]
d1v2aa2_d2b6ma___1	Metazoa		Arthropoda	Proteobacteria	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]		cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]		cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	glutathione transferase activity [GO:0004364]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d1v2ab1_d3i69g2__1	Metazoa	Metazoa	Arthropoda	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione transferase activity [GO:0004364]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1v2ab2_d1guha2__1	Metazoa	Metazoa	Arthropoda	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione transferase activity [GO:0004364]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1v2ac1_d4e8hd2__1	Metazoa	Metazoa	Arthropoda	Arthropoda	glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]					glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d1v2fa__d5xt5a1__1			Deinococcus-Thermus	Firmicutes	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]	cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]; cysteine metabolic process [GO:0006534]	biosynthetic process [GO:0009058]	cysteine metabolic process [GO:0006534]			pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]
d1v2fb__d4mqqa___1			Deinococcus-Thermus	Actinobacteria	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	biosynthetic process [GO:0009058]	biotin biosynthetic process [GO:0009102]		cytoplasm [GO:0005737]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]
d1v2he__d4f3kb___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]		immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]		cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]		drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]	
d1v2ia__d3cl2h___1			Negarnaviricota	Negarnaviricota	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1v2ib__d2htye___1			Negarnaviricota	Negarnaviricota	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1v2ib__d3tiba___1			Negarnaviricota	Negarnaviricota	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1v2vt__d4yo9a___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1v2wt__d4cr5a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d1v2xa__d1ipaa1__1			Deinococcus-Thermus	Deinococcus-Thermus	tRNA (guanosine-2'-O-)-methyltransferase activity [GO:0009020]; tRNA binding [GO:0000049]; tRNA guanine ribose methylation [GO:0002938]	RNA binding [GO:0003723]; RNA methyltransferase activity [GO:0008173]; RNA processing [GO:0006396]	tRNA guanine ribose methylation [GO:0002938]	RNA processing [GO:0006396]			tRNA (guanosine-2'-O-)-methyltransferase activity [GO:0009020]; tRNA binding [GO:0000049]	RNA binding [GO:0003723]; RNA methyltransferase activity [GO:0008173]
d1v2ya1_d3pz8a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U12-type spliceosomal complex [GO:0005689]; mRNA splicing, via spliceosome [GO:0000398]	axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; Rac GTPase binding [GO:0048365]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; collateral sprouting [GO:0048668]; convergent extension involved in neural plate elongation [GO:0022007]; convergent extension involved in organogenesis [GO:0060029]; cytoplasmic microtubule organization [GO:0031122]; dendrite morphogenesis [GO:0048813]; dendritic spine morphogenesis [GO:0060997]; intracellular signal transduction [GO:0035556]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse organization [GO:0099173]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein localization to microtubule [GO:0035372]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cellular protein localization [GO:1903827]; regulation of neurotransmitter levels [GO:0001505]; regulation of protein phosphorylation [GO:0001932]; regulation of synaptic vesicle exocytosis [GO:2000300]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; social behavior [GO:0035176]; synapse organization [GO:0050808]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	mRNA splicing, via spliceosome [GO:0000398]	axon extension [GO:0048675]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; collateral sprouting [GO:0048668]; convergent extension involved in neural plate elongation [GO:0022007]; convergent extension involved in organogenesis [GO:0060029]; cytoplasmic microtubule organization [GO:0031122]; dendrite morphogenesis [GO:0048813]; dendritic spine morphogenesis [GO:0060997]; intracellular signal transduction [GO:0035556]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse organization [GO:0099173]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein localization to microtubule [GO:0035372]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cellular protein localization [GO:1903827]; regulation of neurotransmitter levels [GO:0001505]; regulation of protein phosphorylation [GO:0001932]; regulation of synaptic vesicle exocytosis [GO:2000300]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; social behavior [GO:0035176]; synapse organization [GO:0050808]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U12-type spliceosomal complex [GO:0005689]	axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]		beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; Rac GTPase binding [GO:0048365]
d1v31a1_d4jrgb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	nucleus [GO:0005634]; chromatin organization [GO:0006325]; DNA repair [GO:0006281]; regulation of flower development [GO:0009909]; regulation of gene expression [GO:0010468]; regulation of leaf development [GO:2000024]; response to UV-B [GO:0010224]; root development [GO:0048364]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; metal ion binding [GO:0046872]; transferase activity [GO:0016740]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein ubiquitination [GO:0016567]	chromatin organization [GO:0006325]; DNA repair [GO:0006281]; regulation of flower development [GO:0009909]; regulation of gene expression [GO:0010468]; regulation of leaf development [GO:2000024]; response to UV-B [GO:0010224]; root development [GO:0048364]	negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein ubiquitination [GO:0016567]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]		metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d1v37a__d2wu0a1__1			Deinococcus-Thermus	Proteobacteria	catalytic activity [GO:0003824]	3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]					catalytic activity [GO:0003824]	3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]
d1v3aa__d4qbwa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; prenylated protein tyrosine phosphatase activity [GO:0004727]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cellular response to leukemia inhibitory factor [GO:1990830]; endothelial cell migration [GO:0043542]; Notch signaling pathway [GO:0007219]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of vascular permeability [GO:0043117]; regulation of transcription, DNA-templated [GO:0006355]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cellular response to leukemia inhibitory factor [GO:1990830]; endothelial cell migration [GO:0043542]; Notch signaling pathway [GO:0007219]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of vascular permeability [GO:0043117]; regulation of transcription, DNA-templated [GO:0006355]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	prenylated protein tyrosine phosphatase activity [GO:0004727]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1v3ba__d2sima___1			Negarnaviricota	Proteobacteria	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]; pathogenesis [GO:0009405]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]; pathogenesis [GO:0009405]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]
d1v3ca__d4mx0a___1			Negarnaviricota	Negarnaviricota	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1v3cb__d2bera3__1			Negarnaviricota	Actinobacteria	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	metabolic process [GO:0008152]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1v3cb__d4d8sa___1			Negarnaviricota	Negarnaviricota	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1v3ha__d4b16a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	
d1v3ia__d1ob0a2__1	Viridiplantae		Streptophyta	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1v3ja3_d5brqa2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; alpha,alpha-phosphotrehalase activity [GO:0008788]; metal ion binding [GO:0046872]; trehalose catabolic process [GO:0005993]	carbohydrate metabolic process [GO:0005975]	trehalose catabolic process [GO:0005993]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha,alpha-phosphotrehalase activity [GO:0008788]; metal ion binding [GO:0046872]
d1v3kb1_d1pbya3__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1v3kb1_d2bemc___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	
d1v3kb3_d3edka3__1			Firmicutes	Bacteroidetes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d1v3kb4_d3rilb2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1v3la3_d1cxka3__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1v3la4_d3muib___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	endo-1,4-beta-xylanase activity [GO:0031176]
d1v3ma2_d1j12b1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1v3ma3_d3wmsa2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1v3ma4_d1bgmn5__1			Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	
d1v3mb1_d1j0ha1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1v3mb4_d2gjxa1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	carbohydrate metabolic process [GO:0005975]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d1v3vb2_d1bxza2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; 13-prostaglandin reductase activity [GO:0036132]; 15-oxoprostaglandin 13-oxidase activity [GO:0047522]; 2-alkenal reductase [NAD(P)+] activity [GO:0032440]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]			cytoplasm [GO:0005737]		13-prostaglandin reductase activity [GO:0036132]; 15-oxoprostaglandin 13-oxidase activity [GO:0047522]; 2-alkenal reductase [NAD(P)+] activity [GO:0032440]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]
d1v3zb__d4yhua___1		Fungi	Euryarchaeota	Ascomycota	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	
d1v40a1_d5an1b2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione transferase activity [GO:0004364]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d1v40a2_d1f3ab2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytosol [GO:0005829]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; steroid delta-isomerase activity [GO:0004769]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; steroid delta-isomerase activity [GO:0004769]
d1v40b1_d3wd6c2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d1v40d1_d5ecme2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1v40d2_d2aawa2__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione transferase activity [GO:0004364]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d1v47a2_d1t6ya2__1			Deinococcus-Thermus	Thermotogae	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; sulfate assimilation [GO:0000103]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]; FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	sulfate assimilation [GO:0000103]	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]			metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]
d1v49a__d1lxdb___1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	cytosol [GO:0005829]; nucleus [GO:0005634]; Ral guanyl-nucleotide exchange factor activity [GO:0008321]; small GTPase mediated signal transduction [GO:0007264]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	small GTPase mediated signal transduction [GO:0007264]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	cytosol [GO:0005829]; nucleus [GO:0005634]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]	Ral guanyl-nucleotide exchange factor activity [GO:0008321]
d1v4ja__d3wcdf___1		Metazoa	Thermotogae	Chordata	transferase activity [GO:0016740]; isoprenoid biosynthetic process [GO:0008299]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	isoprenoid biosynthetic process [GO:0008299]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	transferase activity [GO:0016740]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d1v4la__d3kmb11__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]		complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	toxin activity [GO:0090729]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d1v4ld__d2orja1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]		cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	extracellular region [GO:0005576]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1v4le__d2ioub2__1	Metazoa		Chordata		extracellular region [GO:0005576]; toxin activity [GO:0090729]	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]		adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	extracellular region [GO:0005576]	virus tail, fiber [GO:0098024]	toxin activity [GO:0090729]	
d1v4na1_d1nc1a1__1			Crenarchaeota	Proteobacteria	S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	cytosol [GO:0005829]; adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]	L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]		cytosol [GO:0005829]	S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]	adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]
d1v4nb1_d4rj2e___1			Crenarchaeota		S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]		L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]				S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]	
d1v4pb__d1nyqb3__1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]		threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]
d1v4pc__d2e1ba2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; alanine-tRNA ligase activity [GO:0004813]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; alanyl-tRNA aminoacylation [GO:0006419]		alanyl-tRNA aminoacylation [GO:0006419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	alanine-tRNA ligase activity [GO:0004813]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d1v4ra1_d1h9ga1__1			Actinobacteria	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; fatty-acyl-CoA binding [GO:0000062]; fatty acid oxidation [GO:0019395]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fatty acid metabolic process [GO:0019217]		fatty acid oxidation [GO:0019395]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fatty acid metabolic process [GO:0019217]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; fatty-acyl-CoA binding [GO:0000062]
d1v4sa1_d5e26c1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; aerobic respiration [GO:0009060]; coenzyme A biosynthetic process [GO:0015937]; coenzyme biosynthetic process [GO:0009108]; mitochondrion morphogenesis [GO:0070584]; pantothenate metabolic process [GO:0015939]; phosphorylation [GO:0016310]; regulation of bile acid metabolic process [GO:1904251]; regulation of fatty acid metabolic process [GO:0019217]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of triglyceride metabolic process [GO:0090207]; spermatid development [GO:0007286]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	aerobic respiration [GO:0009060]; coenzyme A biosynthetic process [GO:0015937]; coenzyme biosynthetic process [GO:0009108]; mitochondrion morphogenesis [GO:0070584]; pantothenate metabolic process [GO:0015939]; phosphorylation [GO:0016310]; regulation of bile acid metabolic process [GO:1904251]; regulation of fatty acid metabolic process [GO:0019217]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of triglyceride metabolic process [GO:0090207]; spermatid development [GO:0007286]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d1v4sa2_d4f9oa1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d1v4sa2_d4jhdd2__1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]	ATP binding [GO:0005524]
d1v4ua__d3kuob___1	Metazoa	Metazoa	Chordata	Annelida	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d1v4wa__d1j40c___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1v4xd__d1o1kd___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1v4ya3_d1rjpa3__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; N-acyl-D-amino-acid deacylase activity [GO:0047420]	metal ion binding [GO:0046872]; N-acyl-D-amino-acid deacylase activity [GO:0047420]					metal ion binding [GO:0046872]; N-acyl-D-amino-acid deacylase activity [GO:0047420]	metal ion binding [GO:0046872]; N-acyl-D-amino-acid deacylase activity [GO:0047420]
d1v54o1_d1aq8b1__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1v55h__d1oczu___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	ATP synthesis coupled electron transport [GO:0042773]	ATP synthesis coupled electron transport [GO:0042773]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1v57a1_d1wmja___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	cell [GO:0005623]; cytoplasm [GO:0005737]; enzyme inhibitor activity [GO:0004857]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of catalytic activity [GO:0043086]; plasmodesmata-mediated intercellular transport [GO:0010497]; response to cold [GO:0009409]; response to oxidative stress [GO:0006979]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of catalytic activity [GO:0043086]; plasmodesmata-mediated intercellular transport [GO:0010497]; response to cold [GO:0009409]; response to oxidative stress [GO:0006979]	periplasmic space [GO:0042597]	cell [GO:0005623]; cytoplasm [GO:0005737]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	enzyme inhibitor activity [GO:0004857]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]
d1v58a1_d3vi7a1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	periplasmic space [GO:0042597]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1v58a1_d5g1lb2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d1v58b1_d4ecjb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	transferase activity [GO:0016740]			periplasmic space [GO:0042597]		protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	transferase activity [GO:0016740]
d1v5bc__d5hn3a___1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	mitochondrion [GO:0005739]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; homoisocitrate dehydrogenase activity [GO:0047046]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]; lysine biosynthetic process [GO:0009085]	leucine biosynthetic process [GO:0009098]	leucine biosynthetic process [GO:0009098]; lysine biosynthetic process [GO:0009085]	cytoplasm [GO:0005737]	mitochondrion [GO:0005739]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	3-isopropylmalate dehydrogenase activity [GO:0003862]; homoisocitrate dehydrogenase activity [GO:0047046]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1v5be__d2af3d___1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	plasma membrane [GO:0005886]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	leucine biosynthetic process [GO:0009098]	acetyl-CoA biosynthetic process [GO:0006085]	cytoplasm [GO:0005737]	plasma membrane [GO:0005886]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	phosphate acetyltransferase activity [GO:0008959]
d1v5ca__d5gxyb1__1			Firmicutes	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1v5da__d2f6da___1		Fungi	Firmicutes	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	glucan 1,4-alpha-glucosidase activity [GO:0004339]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	glucan 1,4-alpha-glucosidase activity [GO:0004339]
d1v5da__d4l0ga___1			Firmicutes	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d1v5ea2_d1ovmb3__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; auxin biosynthetic process [GO:0009851]		auxin biosynthetic process [GO:0009851]			magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1v5ea3_d2ji9a3__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]		oxalate catabolic process [GO:0033611]			magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d1v5fa3_d2wvaf1__1				Proteobacteria		magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]						magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1v5ga3_d1ovmd2__1				Proteobacteria		indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; auxin biosynthetic process [GO:0009851]		auxin biosynthetic process [GO:0009851]				indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1v5ha__d1y4bd___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]; fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytosol [GO:0005829]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1v5ja1_d4ov6f___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; inhibitory synapse [GO:0060077]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cell-cell adhesion mediator activity [GO:0098632]; axon guidance [GO:0007411]; dendrite development [GO:0016358]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of synapse organization [GO:0050807]	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor recycling [GO:0001920]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	axon guidance [GO:0007411]; dendrite development [GO:0016358]; dendrite self-avoidance [GO:0070593]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of synapse organization [GO:0050807]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of receptor recycling [GO:0001920]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; inhibitory synapse [GO:0060077]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]	cell-cell adhesion mediator activity [GO:0098632]	apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]
d1v5ma1_d4gmxb___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stress fiber [GO:0001725]; identical protein binding [GO:0042802]; SH3/SH2 adaptor activity [GO:0005070]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; actin cytoskeleton organization [GO:0030036]; antigen receptor-mediated signaling pathway [GO:0050851]; B-1 B cell homeostasis [GO:0001922]; brown fat cell differentiation [GO:0050873]; cytokine-mediated signaling pathway [GO:0019221]; glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; negative regulation of glucose import [GO:0046325]; nervous system development [GO:0007399]; regulation of immune response [GO:0050776]; regulation of metabolic process [GO:0019222]; regulation of Ras protein signal transduction [GO:0046578]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	actin cytoskeleton organization [GO:0030036]; antigen receptor-mediated signaling pathway [GO:0050851]; B-1 B cell homeostasis [GO:0001922]; brown fat cell differentiation [GO:0050873]; cytokine-mediated signaling pathway [GO:0019221]; glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; negative regulation of glucose import [GO:0046325]; nervous system development [GO:0007399]; regulation of immune response [GO:0050776]; regulation of metabolic process [GO:0019222]; regulation of Ras protein signal transduction [GO:0046578]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	actin filament [GO:0005884]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stress fiber [GO:0001725]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	identical protein binding [GO:0042802]; SH3/SH2 adaptor activity [GO:0005070]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1v5ta1_d1uela1__1	Metazoa	Metazoa	Chordata	Chordata	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein serine/threonine phosphatase activity [GO:0004722]; protein dephosphorylation [GO:0006470]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle, base subcomplex [GO:0008540]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; RNA binding [GO:0003723]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasome assembly [GO:0043248]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	protein dephosphorylation [GO:0006470]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasome assembly [GO:0043248]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle, base subcomplex [GO:0008540]	protein serine/threonine phosphatase activity [GO:0004722]	identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; RNA binding [GO:0003723]
d1v5ta1_d2d11b3__1	Metazoa	Metazoa	Chordata	Chordata	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein serine/threonine phosphatase activity [GO:0004722]; protein dephosphorylation [GO:0006470]	apical plasma membrane [GO:0016324]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]; protein-containing complex assembly [GO:0065003]	protein dephosphorylation [GO:0006470]	protein-containing complex assembly [GO:0065003]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	apical plasma membrane [GO:0016324]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	protein serine/threonine phosphatase activity [GO:0004722]	beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]
d1v5va1_d3a8ia2__1			Euryarchaeota	Proteobacteria	aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]; glycine decarboxylation via glycine cleavage system [GO:0019464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]; lipoic acid binding [GO:0031405]; glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]	aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]	lipoic acid binding [GO:0031405]
d1v5va2_d3a8kc1__1			Euryarchaeota	Proteobacteria	aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]; glycine decarboxylation via glycine cleavage system [GO:0019464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]; lipoic acid binding [GO:0031405]; glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]	aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]	lipoic acid binding [GO:0031405]
d1v5vb2_d1xzqb1__1			Euryarchaeota	Thermotogae	aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]; glycine decarboxylation via glycine cleavage system [GO:0019464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]	glycine decarboxylation via glycine cleavage system [GO:0019464]	tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]
d1v5xa__d5tqlb___1			Deinococcus-Thermus	Thermotogae	phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	cytoplasm [GO:0005737]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; histidine biosynthetic process [GO:0000105]	tryptophan biosynthetic process [GO:0000162]	histidine biosynthetic process [GO:0000105]		cytoplasm [GO:0005737]	phosphoribosylanthranilate isomerase activity [GO:0004640]	imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]
d1v5xb__d3p5ya___1			Deinococcus-Thermus	Euryarchaeota	phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			phosphoribosylanthranilate isomerase activity [GO:0004640]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1v5zb__d1f5vb___1			Proteobacteria	Proteobacteria	oxidoreductase activity [GO:0016491]; bioluminescence [GO:0008218]	cytosol [GO:0005829]; chromate reductase activity [GO:0034567]; FMN binding [GO:0010181]; oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor [GO:0016657]	bioluminescence [GO:0008218]			cytosol [GO:0005829]	oxidoreductase activity [GO:0016491]	chromate reductase activity [GO:0034567]; FMN binding [GO:0010181]; oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor [GO:0016657]
d1v63a1_d3nm9p___1	Metazoa	Metazoa	Chordata	Arthropoda	fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]; RNA polymerase I upstream control element sequence-specific DNA binding [GO:0001165]; scaffold protein binding [GO:0097110]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin silencing at rDNA [GO:0000183]; positive regulation of transcription by RNA polymerase I [GO:0045943]; transcription by RNA polymerase I [GO:0006360]; transcription elongation from RNA polymerase I promoter [GO:0006362]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]; chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	cellular response to leukemia inhibitory factor [GO:1990830]; chromatin silencing at rDNA [GO:0000183]; positive regulation of transcription by RNA polymerase I [GO:0045943]; transcription by RNA polymerase I [GO:0006360]; transcription elongation from RNA polymerase I promoter [GO:0006362]	chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]; RNA polymerase I upstream control element sequence-specific DNA binding [GO:0001165]; scaffold protein binding [GO:0097110]	AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]
d1v6ab1_d3zv6a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity [GO:0018509]; aromatic compound catabolic process [GO:0019439]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity [GO:0018509]
d1v6ab2_d4kdea2__1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]
d1v6cb__d5faxa1__1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1v6da__d1wnqa___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	
d1v6fa1_d4cbug___1	Metazoa	Metazoa	Chordata	Chordata	actin cortical patch [GO:0030479]; actin binding [GO:0003779]; Arp2/3 complex binding [GO:0071933]; growth factor activity [GO:0008083]; actin filament debranching [GO:0071846]; learning [GO:0007612]; locomotory behavior [GO:0007626]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; actin polymerization or depolymerization [GO:0008154]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; barbed-end actin filament capping [GO:0051016]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]; vesicle-mediated transport [GO:0016192]	actin filament debranching [GO:0071846]; learning [GO:0007612]; locomotory behavior [GO:0007626]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; actin polymerization or depolymerization [GO:0008154]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; barbed-end actin filament capping [GO:0051016]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]; vesicle-mediated transport [GO:0016192]	actin cortical patch [GO:0030479]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]	actin binding [GO:0003779]; Arp2/3 complex binding [GO:0071933]; growth factor activity [GO:0008083]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1v6ib__d3azyc___1	Viridiplantae		Streptophyta	Thermotogae	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1v6id__d1vlnh___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1v6ja__d3v64b___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; dendrite [GO:0030425]; integral component of membrane [GO:0016021]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; apolipoprotein binding [GO:0034185]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; receptor tyrosine kinase binding [GO:0030971]; scaffold protein binding [GO:0097110]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055]		amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055]		cell surface [GO:0009986]; dendrite [GO:0030425]; integral component of membrane [GO:0016021]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	apolipoprotein binding [GO:0034185]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; receptor tyrosine kinase binding [GO:0030971]; scaffold protein binding [GO:0097110]
d1v6ja__d4pf5a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1v6jb__d2a6vb___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]		endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]		COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1v6jd__d3c2uc2__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1v6kb__d2e51d___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1v6kc__d1w0oa2__1	Viridiplantae		Streptophyta	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]; ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]		ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]
d1v6kd__d1h46x___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1v6lb__d2zhmd___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]
d1v6ma__d1gnha___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1v6ma__d1n3pa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1v6mc__d3l2yi___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1v6mf__d2xspa___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1v6mg__d2jd4b1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	basement membrane [GO:0005604]; cell-cell junction [GO:0005911]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; laminin complex [GO:0043256]; laminin-1 complex [GO:0005606]; laminin-3 complex [GO:0005608]; membrane [GO:0016020]; extracellular matrix structural constituent [GO:0005201]; glycosphingolipid binding [GO:0043208]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; blood vessel morphogenesis [GO:0048514]; branching involved in salivary gland morphogenesis [GO:0060445]; camera-type eye development [GO:0043010]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of epithelial cell apical/basal polarity [GO:0045198]; morphogenesis of an epithelial sheet [GO:0002011]; neuron projection development [GO:0031175]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; retina development in camera-type eye [GO:0060041]; retinal blood vessel morphogenesis [GO:0061304]; tissue development [GO:0009888]		animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; blood vessel morphogenesis [GO:0048514]; branching involved in salivary gland morphogenesis [GO:0060445]; camera-type eye development [GO:0043010]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of epithelial cell apical/basal polarity [GO:0045198]; morphogenesis of an epithelial sheet [GO:0002011]; neuron projection development [GO:0031175]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; retina development in camera-type eye [GO:0060041]; retinal blood vessel morphogenesis [GO:0061304]; tissue development [GO:0009888]		basement membrane [GO:0005604]; cell-cell junction [GO:0005911]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; laminin-1 complex [GO:0005606]; laminin-3 complex [GO:0005608]; laminin complex [GO:0043256]; membrane [GO:0016020]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular matrix structural constituent [GO:0005201]; glycosphingolipid binding [GO:0043208]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]
d1v6mh__d4ym3c___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]		cell adhesion [GO:0007155]		collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d1v6na__d1bxha___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1v6na__d1slcc___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]; apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]		apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]		extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]
d1v6nb__d1teih___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1v6nd__d1ww4b___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]		apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d1v6ne__d5kxbb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1v6nf__d1lu2a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]
d1v6nf__d3pvnk___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1v6nh__d2es3b___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]; activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]		activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]
d1v6oc__d2e7qa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1v6og__d1gnhd___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d1v6oh__d2r1dg1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]		angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]		axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]
d1v6sb__d5bt8b1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]	ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]
d1v6ua2_d2fgla___1			Actinobacteria	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]
d1v6vb2_d1qvbb___1			Actinobacteria	Crenarchaeota	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1v6wa1_d1pumb1__1		Viridiplantae	Actinobacteria	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	polysaccharide catabolic process [GO:0000272]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1v6xb2_d1xh1a2__1		Metazoa	Actinobacteria	Chordata	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	polysaccharide catabolic process [GO:0000272]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endo-1,4-beta-xylanase activity [GO:0031176]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1v6ya1_d4w87b___1			Actinobacteria		endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]
d1v72a1_d1asfa___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; threonine aldolase activity [GO:0004793]; threonine catabolic process [GO:0006567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	threonine catabolic process [GO:0006567]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	metal ion binding [GO:0046872]; threonine aldolase activity [GO:0004793]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1v77a__d3wz0e___1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ribonuclease P complex [GO:0030677]; ribonuclease P activity [GO:0004526]; tRNA 5'-leader removal [GO:0001682]	cytoplasm [GO:0005737]; ribonuclease MRP complex [GO:0000172]; ribonuclease P complex [GO:0030677]; ribonuclease P activity [GO:0004526]; rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682]; tRNA processing [GO:0008033]	tRNA 5'-leader removal [GO:0001682]	rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; ribonuclease P complex [GO:0030677]	cytoplasm [GO:0005737]; ribonuclease MRP complex [GO:0000172]; ribonuclease P complex [GO:0030677]	ribonuclease P activity [GO:0004526]	ribonuclease P activity [GO:0004526]
d1v78a__d2bb0a2__1				Firmicutes		cytoplasm [GO:0005737]; imidazolonepropionase activity [GO:0050480]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]; histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]		histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]		cytoplasm [GO:0005737]		imidazolonepropionase activity [GO:0050480]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]
d1v7cb__d4d9ed___1			Deinococcus-Thermus	Proteobacteria	pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]; threonine biosynthetic process [GO:0009088]	D-cysteine desulfhydrase activity [GO:0019148]; D-amino acid metabolic process [GO:0046416]	threonine biosynthetic process [GO:0009088]	D-amino acid metabolic process [GO:0046416]			pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]	D-cysteine desulfhydrase activity [GO:0019148]
d1v7cd__d1j0bm___1			Deinococcus-Thermus	Euryarchaeota	pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]; threonine biosynthetic process [GO:0009088]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]	threonine biosynthetic process [GO:0009088]				pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]
d1v7la__d1amja1__1		Metazoa	Euryarchaeota	Chordata	3-isopropylmalate dehydratase activity [GO:0003861]; leucine biosynthetic process [GO:0009098]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	3-isopropylmalate dehydratase activity [GO:0003861]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]
d1v7mh1_d4ht1l2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cell differentiation [GO:0030154]; endothelial cell migration [GO:0043542]; extrinsic apoptotic signaling pathway [GO:0097191]; immune response [GO:0006955]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of protein catabolic process [GO:0045732]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cell differentiation [GO:0030154]; endothelial cell migration [GO:0043542]; extrinsic apoptotic signaling pathway [GO:0097191]; immune response [GO:0006955]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of protein catabolic process [GO:0045732]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]
d1v7mh1_d4tuod1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]		cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	
d1v7mh2_d4nhud1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	
d1v7mm2_d4zs7l1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]
d1v7nh1_d1pkqg1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	signaling receptor binding [GO:0005102]
d1v7nh2_d4lhjb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	endoplasmic reticulum [GO:0005783]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d1v7ni1_d3qeqd2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1v7nj1_d1koaa1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	A band [GO:0031672]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; structural constituent of muscle [GO:0008307]; adult locomotory behavior [GO:0008344]; behavioral response to nicotine [GO:0035095]; muscle contraction [GO:0006936]; negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of locomotion [GO:0040017]; positive regulation of sarcomere organization [GO:0060298]; positive regulation of striated muscle contraction [GO:0045989]; sarcomere organization [GO:0045214]; striated muscle myosin thick filament assembly [GO:0071688]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	adult locomotory behavior [GO:0008344]; behavioral response to nicotine [GO:0035095]; muscle contraction [GO:0006936]; negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of locomotion [GO:0040017]; positive regulation of sarcomere organization [GO:0060298]; positive regulation of striated muscle contraction [GO:0045989]; sarcomere organization [GO:0045214]; striated muscle myosin thick filament assembly [GO:0071688]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	A band [GO:0031672]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; structural constituent of muscle [GO:0008307]
d1v7nj2_d1i9rk2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]; activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	activation of JUN kinase activity [GO:0007257]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; immunoglobulin secretion [GO:0048305]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; isotype switching [GO:0045190]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of apoptotic process [GO:0043066]; platelet activation [GO:0030168]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	CD40 receptor binding [GO:0005174]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; tumor necrosis factor receptor binding [GO:0005164]
d1v7nk1_d2gaza1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1v7nl2_d3tvmb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	
d1v7nm1_d4xbpf1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]		cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	
d1v7nm1_d5i8ed1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]		cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	
d1v7nn1_d4l29u2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1v7nv__d1wu3i___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; chloramphenicol O-acetyltransferase activity [GO:0008811]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; B cell activation involved in immune response [GO:0002312]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to dsRNA [GO:0071359]; cellular response to interferon-beta [GO:0035458]; cellular response to virus [GO:0098586]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; macrophage activation involved in immune response [GO:0002281]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	adaptive immune response [GO:0002250]; B cell activation involved in immune response [GO:0002312]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to dsRNA [GO:0071359]; cellular response to interferon-beta [GO:0035458]; cellular response to virus [GO:0098586]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; macrophage activation involved in immune response [GO:0002281]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	chloramphenicol O-acetyltransferase activity [GO:0008811]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]
d1v7nx__d1irla___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; cytokine activity [GO:0005125]; glycosphingolipid binding [GO:0043208]; growth factor activity [GO:0008083]; interleukin-2 receptor binding [GO:0005134]; kappa-type opioid receptor binding [GO:0031851]; kinase activator activity [GO:0019209]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; immune response [GO:0006955]; interleukin-2-mediated signaling pathway [GO:0038110]; leukocyte activation involved in immune response [GO:0002366]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of heart contraction [GO:0045822]; negative regulation of inflammatory response [GO:0050728]; negative regulation of lymphocyte proliferation [GO:0050672]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; response to ethanol [GO:0045471]; T cell differentiation [GO:0030217]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; immune response [GO:0006955]; interleukin-2-mediated signaling pathway [GO:0038110]; leukocyte activation involved in immune response [GO:0002366]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of heart contraction [GO:0045822]; negative regulation of inflammatory response [GO:0050728]; negative regulation of lymphocyte proliferation [GO:0050672]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; response to ethanol [GO:0045471]; T cell differentiation [GO:0030217]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]	carbohydrate binding [GO:0030246]; cytokine activity [GO:0005125]; glycosphingolipid binding [GO:0043208]; growth factor activity [GO:0008083]; interleukin-2 receptor binding [GO:0005134]; kappa-type opioid receptor binding [GO:0031851]; kinase activator activity [GO:0019209]
d1v7pb__d4j6ma___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d1v7pb__d4n35c___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]		antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	extracellular region [GO:0005576]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1v7qa__d2hpad___1		Metazoa	Deinococcus-Thermus	Chordata	catalytic activity [GO:0003824]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]; adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]		adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]		azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	catalytic activity [GO:0003824]	5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]
d1v7ra__d4p0ea___1			Euryarchaeota	Proteobacteria	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	cytoplasm [GO:0005737]; dTTP diphosphatase activity [GO:0036218]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; UTP diphosphatase activity [GO:0036221]; nucleotide metabolic process [GO:0009117]	nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleotide metabolic process [GO:0009117]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]	dTTP diphosphatase activity [GO:0036218]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; UTP diphosphatase activity [GO:0036221]
d1v7va2_d1lf6a2__1			Proteobacteria	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; transferase activity [GO:0016740]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; polysaccharide metabolic process [GO:0005976]	carbohydrate metabolic process [GO:0005975]	polysaccharide metabolic process [GO:0005976]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; transferase activity [GO:0016740]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]
d1v7zc__d3a6fa___1			Proteobacteria	Proteobacteria	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]			creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]
d1v80a__d4ii3d___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; ubiquitin activating enzyme activity [GO:0004839]; cellular response to DNA damage stimulus [GO:0006974]; protein modification by small protein conjugation [GO:0032446]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cellular response to DNA damage stimulus [GO:0006974]; protein modification by small protein conjugation [GO:0032446]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; ubiquitin activating enzyme activity [GO:0004839]
d1v8ba1_d3qwhd___1		Fungi	Apicomplexa	Ascomycota	cytosol [GO:0005829]; adenosylhomocysteinase activity [GO:0004013]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353]		cytosol [GO:0005829]		adenosylhomocysteinase activity [GO:0004013]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1v8fa__d4r0na___1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]; pantothenate biosynthetic process [GO:0015940]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	pantothenate biosynthetic process [GO:0015940]	coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1v8ga1_d1k8eb1__1			Deinococcus-Thermus		anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]		tryptophan biosynthetic process [GO:0000162]				anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	
d1v8ga1_d4yeka1__1			Deinococcus-Thermus	Proteobacteria	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]	tryptophan biosynthetic process [GO:0000162]	pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]		cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1v8pl__d5h4hb___1			Crenarchaeota	Euryarchaeota	exonuclease activity [GO:0004527]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]	magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]					exonuclease activity [GO:0004527]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]	magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]
d1v8xa__d1otwb1__1			Actinobacteria	Proteobacteria	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	pyrroloquinoline-quinone synthase activity [GO:0033732]; pyrroloquinoline quinone biosynthetic process [GO:0018189]	heme oxidation [GO:0006788]	pyrroloquinoline quinone biosynthetic process [GO:0018189]			heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	pyrroloquinoline-quinone synthase activity [GO:0033732]
d1v8xb__d1s8ca___1		Metazoa	Actinobacteria	Chordata	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	heme oxidation [GO:0006788]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]		caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1v8xb__d1sk7a___1			Actinobacteria	Proteobacteria	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	heme oxygenase (decyclizing) activity [GO:0004392]; heme oxidation [GO:0006788]	heme oxidation [GO:0006788]	heme oxidation [GO:0006788]			heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	heme oxygenase (decyclizing) activity [GO:0004392]
d1v8za1_d2zsjc___1			Euryarchaeota	Aquificae	tryptophan synthase activity [GO:0004834]	cytoplasm [GO:0005737]; pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]; threonine biosynthetic process [GO:0009088]		threonine biosynthetic process [GO:0009088]		cytoplasm [GO:0005737]	tryptophan synthase activity [GO:0004834]	pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]
d1v8zc__d3vsab___1			Euryarchaeota	Crenarchaeota	tryptophan synthase activity [GO:0004834]	cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]; cysteine biosynthetic process from serine [GO:0006535]		cysteine biosynthetic process from serine [GO:0006535]			tryptophan synthase activity [GO:0004834]	cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]
d1v94a__d2qfxb___1		Fungi	Crenarchaeota	Ascomycota	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; tricarboxylic acid cycle [GO:0006099]	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]		mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1v95a1_d1nj8b1__1	Metazoa		Chordata	Euryarchaeota	actin cytoskeleton [GO:0015629]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; RNA binding [GO:0003723]; glucose homeostasis [GO:0042593]; negative regulation of insulin receptor signaling pathway [GO:0046627]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; proline-tRNA ligase activity [GO:0004827]; prolyl-tRNA aminoacylation [GO:0006433]	glucose homeostasis [GO:0042593]; negative regulation of insulin receptor signaling pathway [GO:0046627]	prolyl-tRNA aminoacylation [GO:0006433]	actin cytoskeleton [GO:0015629]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	chromatin binding [GO:0003682]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; proline-tRNA ligase activity [GO:0004827]
d1v97a1_d5g5ha2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	periplasmic space [GO:0042597]; carboxylate reductase activity [GO:0047770]; molybdenum ion binding [GO:0030151]; oxidoreductase activity, acting on the aldehyde or oxo group of donors [GO:0016903]; cellular response to DNA damage stimulus [GO:0006974]	xanthine catabolic process [GO:0009115]	cellular response to DNA damage stimulus [GO:0006974]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	periplasmic space [GO:0042597]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	carboxylate reductase activity [GO:0047770]; molybdenum ion binding [GO:0030151]; oxidoreductase activity, acting on the aldehyde or oxo group of donors [GO:0016903]
d1v97a4_d3b9jb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1v97b2_d2bt6a2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	xanthine catabolic process [GO:0009115]	cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]
d1v97b4_d3eub32__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1v98a__d4e8hb1__1		Metazoa	Deinococcus-Thermus	Arthropoda	cell [GO:0005623]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	transferase activity [GO:0016740]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]		metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	transferase activity [GO:0016740]
d1v98b__d1pn0a2__1		Fungi	Deinococcus-Thermus	Basidiomycota	cell [GO:0005623]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]; phenol-containing compound catabolic process [GO:0019336]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	phenol-containing compound catabolic process [GO:0019336]	cell [GO:0005623]		metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]
d1v98b__d5abrb___1			Deinococcus-Thermus	Proteobacteria	cell [GO:0005623]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; nitrogen fixation [GO:0009399]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	nitrogen fixation [GO:0009399]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]		metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]
d1v9la2_d4bhtc1__1			Crenarchaeota	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	cellular amino acid metabolic process [GO:0006520]	glutamate biosynthetic process [GO:0006537]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]
d1v9lb2_d1nr7h2__1		Metazoa	Crenarchaeota	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1v9lc2_d1nqtb2__1		Metazoa	Crenarchaeota	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1v9lc2_d2hk7b1__1			Crenarchaeota	Aquificae	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1v9le1_d3mvqd2__1			Crenarchaeota		nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]				nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	
d1v9lf2_d3tnld1__1			Crenarchaeota	Firmicutes	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d1v9pa1_d1dgta6__1			Deinococcus-Thermus		DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]		DNA repair [GO:0006281]; DNA replication [GO:0006260]				DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]	
d1v9pa2_d2qp0l1__1			Deinococcus-Thermus		DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]		DNA repair [GO:0006281]; DNA replication [GO:0006260]				DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]	
d1v9pa3_d4ucsa___1			Deinococcus-Thermus	Proteobacteria	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; base-excision repair, DNA ligation [GO:0006288]; DNA replication [GO:0006260]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	base-excision repair, DNA ligation [GO:0006288]; DNA replication [GO:0006260]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]
d1v9pb1_d1ixrb2__1			Deinococcus-Thermus	Deinococcus-Thermus	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]			DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]
d1v9u1__d2bful1__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	transport of virus in host, cell to cell [GO:0046740]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1v9wa1_d1okda1__1	Metazoa		Chordata		cytosol [GO:0005829]; peroxidase activity [GO:0004601]; protein-disulfide reductase activity [GO:0047134]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]	cell [GO:0005623]	peroxidase activity [GO:0004601]; protein-disulfide reductase activity [GO:0047134]	
d1va4a__d4wcva1__1			Proteobacteria	Actinobacteria	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]		response to toxic substance [GO:0009636]			arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	haloalkane dehalogenase activity [GO:0018786]
d1va4b__d4oyyi___1		Fungi	Proteobacteria	Ascomycota	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]				extracellular region [GO:0005576]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	cutinase activity [GO:0050525]
d1va4c__d3hi4d___1			Proteobacteria	Proteobacteria	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]					arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]
d1va4d__d1uoqa2__1		Metazoa	Proteobacteria	Chordata	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]				cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d1va4d__d3hi4b___1			Proteobacteria	Proteobacteria	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]					arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]
d1va5a__d1qima___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	cell wall [GO:0005618]; extracellular region [GO:0005576]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]	acetylcholinesterase activity [GO:0003990]
d1va9a1_d6b2ac___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; synapse [GO:0045202]; cell-cell adhesion mediator activity [GO:0098632]; protein homodimerization activity [GO:0042803]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; brain development [GO:0007420]; cell fate determination [GO:0001709]; central nervous system development [GO:0007417]; dendrite self-avoidance [GO:0070593]; dorsal/ventral pattern formation [GO:0009953]; embryonic skeletal system morphogenesis [GO:0048704]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	integral component of plasma membrane [GO:0005887]; inorganic anion transmembrane transporter activity [GO:0015103]	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; brain development [GO:0007420]; cell fate determination [GO:0001709]; central nervous system development [GO:0007417]; dendrite self-avoidance [GO:0070593]; dorsal/ventral pattern formation [GO:0009953]; embryonic skeletal system morphogenesis [GO:0048704]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]		axon [GO:0030424]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; synapse [GO:0045202]	integral component of plasma membrane [GO:0005887]	cell-cell adhesion mediator activity [GO:0098632]; protein homodimerization activity [GO:0042803]	inorganic anion transmembrane transporter activity [GO:0015103]
d1vaca1_d1oqxa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1vaca1_d4olwl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	structural molecule activity [GO:0005198]
d1vaca2_d1seba2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1vacb__d5d6da2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	IgG binding [GO:0019864]
d1vaea1_d1n6fc1__1	Metazoa		Chordata	Euryarchaeota	perinuclear region of cytoplasm [GO:0048471]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	signal transduction [GO:0007165]	proteolysis [GO:0006508]	perinuclear region of cytoplasm [GO:0048471]	cytoplasm [GO:0005737]		serine-type peptidase activity [GO:0008236]
d1vaha1_d1izka2__1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1vaka__d5fmol1__1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]		transport of virus in host, cell to cell [GO:0046740]	viral capsid [GO:0019028]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1vama__d1dzqb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1vama__d5t52a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]				extracellular region [GO:0005576]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1vamb__d1uleb___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]				cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1vamc__d1qmo.2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	protein storage vacuole lumen [GO:0034495]; carbohydrate binding [GO:0030246]				protein storage vacuole lumen [GO:0034495]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1vaoa1_d1qlub1__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1vaoa1_d5fxpa2__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]		FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1vara2_d3lj9a2__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1varb1_d3ak1d1__1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1vaxa2_d1gtpk___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1vaxb1_d5m98e2__1		Metazoa		Chordata		peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]
d1vaxc1_d1r56b1__1		Fungi		Ascomycota		peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]
d1vaxc2_d1xy3a1__1		Fungi		Ascomycota		peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]
d1vaxf1_d3pkga1__1		Fungi		Ascomycota		peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]
d1vaxf2_d1a8rn___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1vaxh1_d1vayc2__1												
d1vaxh2_d1gtph___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1vaya1_d1n3tm___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1vaya2_d1n3ro___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1vayb1_d2icqa1__1		Fungi		Ascomycota		peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]
d1vayb1_d3qn0c___1				Proteobacteria		6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]		queuosine biosynthetic process [GO:0008616]				6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d1vayb2_d3plea2__1		Fungi		Ascomycota		peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]
d1vayc2_d1a9cm___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1vayd2_d3qn0f___1				Proteobacteria		6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]		queuosine biosynthetic process [GO:0008616]				6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d1vaye1_d1n3rn___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1vaye2_d1wplc___1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]		negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]
d1vayf1_d1fbxf___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1vayf2_d1a8rd___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1vayg1_d1rsda___1				Firmicutes		dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]		folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]
d1vayh2_d1n3ta___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]		GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1vb2a__d1na1c___1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1vb3a1_d1j0bq___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]; threonine biosynthetic process [GO:0009088]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]	threonine biosynthetic process [GO:0009088]		cytosol [GO:0005829]		pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]	1-aminocyclopropane-1-carboxylate deaminase activity [GO:0008660]
d1vb3a1_d4d9bb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]; threonine biosynthetic process [GO:0009088]	D-cysteine desulfhydrase activity [GO:0019148]; D-amino acid metabolic process [GO:0046416]	threonine biosynthetic process [GO:0009088]	D-amino acid metabolic process [GO:0046416]	cytosol [GO:0005829]		pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]	D-cysteine desulfhydrase activity [GO:0019148]
d1vb5b__d4eu4a1__1			Euryarchaeota	Proteobacteria	translation initiation factor activity [GO:0003743]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]		acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]			translation initiation factor activity [GO:0003743]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d1vb9a1_d1cxfa1__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1vb9a1_d4x42d1__1			Firmicutes		metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1vb9a3_d1xsia4__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1vb9b3_d1ukob___1		Viridiplantae	Firmicutes	Streptophyta	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d1vba1__d1opob___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1vba3__d2gsyr___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; T=13 icosahedral viral capsid [GO:0039621]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasm [GO:0030430]; T=13 icosahedral viral capsid [GO:0039621]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]
d1vbb1__d4y4yn___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1vbb3__d1k5m.1__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1vbc3__d4y4yq___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1vbd3__d1bev3___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1vbd3__d2df7b___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; viral capsid [GO:0019028]; host cell surface binding [GO:0046812]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell cytoplasm [GO:0030430]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	host cell surface binding [GO:0046812]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]
d1vbe3__d4y4ye___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1vbla__d1nhca___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; lyase activity [GO:0016829]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	lyase activity [GO:0016829]	polygalacturonase activity [GO:0004650]
d1vbma__d4zcsd___1			Proteobacteria	Apicomplexa	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]; tRNA aminoacylation [GO:0043039]; tyrosyl-tRNA aminoacylation [GO:0006437]	choline-phosphate cytidylyltransferase activity [GO:0004105]; identical protein binding [GO:0042802]; phosphatidylcholine binding [GO:0031210]	tRNA aminoacylation [GO:0043039]; tyrosyl-tRNA aminoacylation [GO:0006437]		cytosol [GO:0005829]; membrane [GO:0016020]		ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]	choline-phosphate cytidylyltransferase activity [GO:0004105]; identical protein binding [GO:0042802]; phosphatidylcholine binding [GO:0031210]
d1vbob__d1ugw.4__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]
d1vbra1_d1jyyg5__1			Thermotogae		endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	
d1vbua__d1iexa1__1		Viridiplantae	Thermotogae	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1vbub__d3viha___1		Metazoa	Thermotogae	Arthropoda	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1vbxa__d1ft8a2__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1vbya__d3rw7c1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1vbya__d4zkab___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; trans-Golgi network [GO:0005802]; mRNA binding [GO:0003729]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; mRNA processing [GO:0006397]; nervous system development [GO:0007399]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; RNA transport [GO:0050658]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	mRNA processing [GO:0006397]; nervous system development [GO:0007399]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; RNA transport [GO:0050658]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; trans-Golgi network [GO:0005802]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	mRNA binding [GO:0003729]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]
d1vbza__d2diva1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; RNA binding [GO:0003723]; selenocysteine incorporation [GO:0001514]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	selenocysteine incorporation [GO:0001514]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	RNA binding [GO:0003723]
d1vc6a__d3p5tm___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]
d1vc8a1_d3shdb___1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [GO:0016818]; metal ion binding [GO:0046872]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]					ATP binding [GO:0005524]; hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [GO:0016818]; metal ion binding [GO:0046872]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]
d1vc9b__d5c8la___1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [GO:0016818]; metal ion binding [GO:0046872]	ADP-ribose diphosphatase activity [GO:0047631]					ATP binding [GO:0005524]; hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [GO:0016818]; metal ion binding [GO:0046872]	ADP-ribose diphosphatase activity [GO:0047631]
d1vcaa1_d1u8ib1__1	Metazoa		Chordata		alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]		acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell chemotaxis [GO:0060326]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]		alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]		cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]	
d1vcab2_d1ie5a1__1	Metazoa	Metazoa	Chordata	Chordata	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synaptic membrane adhesion [GO:0099560]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell chemotaxis [GO:0060326]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synaptic membrane adhesion [GO:0099560]	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]	
d1vcab2_d4l29x1__1	Metazoa	Metazoa	Chordata	Chordata	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell chemotaxis [GO:0060326]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1vcbj__d5aekv___1	Metazoa	Metazoa	Chordata	Chordata	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	ubiquitin protein ligase binding [GO:0031625]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d1vcja__d4geza___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1vcla1_d5bp5a2__1	Metazoa		Echinodermata	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]						carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	
d1vcla2_d2e4mb1__1	Metazoa		Echinodermata		carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	
d1vclb1_d1dqoa___1	Metazoa	Metazoa	Echinodermata	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cargo receptor activity [GO:0038024]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]		cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]		cell surface [GO:0009986]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cargo receptor activity [GO:0038024]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]
d1vclb1_d3aj6a2__1	Metazoa		Echinodermata		carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1vcpa__d1tpsa___1		Metazoa		Chordata	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1vcqb__d1z8yq1__1					host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]
d1vcsa1_d1hs7a___1	Metazoa	Fungi	Chordata	Ascomycota	autophagosome [GO:0005776]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; SNARE complex [GO:0031201]; synaptic vesicle [GO:0008021]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; autophagy [GO:0006914]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi ribbon formation [GO:0090161]; Golgi to vacuole transport [GO:0006896]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein targeting to vacuole [GO:0006623]; retrograde transport, endosome to Golgi [GO:0042147]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion with Golgi apparatus [GO:0048280]; voluntary musculoskeletal movement [GO:0050882]	endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; integral component of membrane [GO:0016021]; SNARE complex [GO:0031201]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; autophagosome maturation [GO:0097352]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; piecemeal microautophagy of the nucleus [GO:0034727]; vacuole fusion, non-autophagic [GO:0042144]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]; vesicle fusion with vacuole [GO:0051469]	autophagy [GO:0006914]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi ribbon formation [GO:0090161]; Golgi to vacuole transport [GO:0006896]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein targeting to vacuole [GO:0006623]; retrograde transport, endosome to Golgi [GO:0042147]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion with Golgi apparatus [GO:0048280]; voluntary musculoskeletal movement [GO:0050882]	autophagosome maturation [GO:0097352]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; piecemeal microautophagy of the nucleus [GO:0034727]; vacuole fusion, non-autophagic [GO:0042144]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]; vesicle fusion with vacuole [GO:0051469]	autophagosome [GO:0005776]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]; perinuclear region of cytoplasm [GO:0048471]; SNARE complex [GO:0031201]; synaptic vesicle [GO:0008021]	endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; integral component of membrane [GO:0016021]; SNARE complex [GO:0031201]	SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]	SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]
d1vcva1_d5hudb___1			Crenarchaeota	Actinobacteria	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	chorismate metabolic process [GO:0046417]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]		deoxyribose-phosphate aldolase activity [GO:0004139]	
d1vd1a__d1iybb1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	nucleotide binding [GO:0000166]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]					nucleotide binding [GO:0000166]; ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]	ribonuclease T2 activity [GO:0033897]; RNA binding [GO:0003723]
d1vd2a1_d2kfka1__1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; intercellular bridge [GO:0045171]; microtubule cytoskeleton [GO:0015630]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; Schmidt-Lanterman incisure [GO:0043220]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phospholipid binding [GO:0005543]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; actin filament organization [GO:0007015]; bicellular tight junction assembly [GO:0070830]; cell migration [GO:0016477]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; cytoskeleton organization [GO:0007010]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; eye photoreceptor cell development [GO:0042462]; Golgi vesicle budding [GO:0048194]; intracellular signal transduction [GO:0035556]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of glucose import [GO:0046326]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein phosphorylation [GO:0006468]; protein targeting to membrane [GO:0006612]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to interleukin-1 [GO:0070555]; secretion [GO:0046903]; vesicle-mediated transport [GO:0016192]	Cdc24p-Far1p-Gbetagamma complex [GO:0120171]; cell division site [GO:0032153]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; division septum [GO:0000935]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]; nucleus [GO:0005634]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; cellular bud site selection [GO:0000282]; chemotropism [GO:0043577]; protein localization to cell cortex [GO:0072697]; regulation of exit from mitosis [GO:0007096]; regulation of Rho protein signal transduction [GO:0035023]; septin ring organization [GO:0031106]; small GTPase mediated signal transduction [GO:0007264]	actin filament organization [GO:0007015]; bicellular tight junction assembly [GO:0070830]; cell-cell junction organization [GO:0045216]; cell migration [GO:0016477]; cellular response to insulin stimulus [GO:0032869]; cytoskeleton organization [GO:0007010]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; eye photoreceptor cell development [GO:0042462]; Golgi vesicle budding [GO:0048194]; intracellular signal transduction [GO:0035556]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of glucose import [GO:0046326]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein phosphorylation [GO:0006468]; protein targeting to membrane [GO:0006612]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to interleukin-1 [GO:0070555]; secretion [GO:0046903]; vesicle-mediated transport [GO:0016192]	cellular bud site selection [GO:0000282]; chemotropism [GO:0043577]; protein localization to cell cortex [GO:0072697]; regulation of exit from mitosis [GO:0007096]; regulation of Rho protein signal transduction [GO:0035023]; septin ring organization [GO:0031106]; small GTPase mediated signal transduction [GO:0007264]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; intercellular bridge [GO:0045171]; microtubule cytoskeleton [GO:0015630]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; Schmidt-Lanterman incisure [GO:0043220]	Cdc24p-Far1p-Gbetagamma complex [GO:0120171]; cell division site [GO:0032153]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; division septum [GO:0000935]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]; nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phospholipid binding [GO:0005543]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]	Rho guanyl-nucleotide exchange factor activity [GO:0005089]
d1vd6a__d5ptda___1			Deinococcus-Thermus	Firmicutes	phosphoric diester hydrolase activity [GO:0008081]; lipid metabolic process [GO:0006629]	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	lipid metabolic process [GO:0006629]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	phosphoric diester hydrolase activity [GO:0008081]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]
d1vdhb__d3mm1a___1		Fungi	Deinococcus-Thermus	Basidiomycota	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1vdhc__d1t0tx___1			Deinococcus-Thermus	Firmicutes	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1vdhe__d2znze2__1			Deinococcus-Thermus	Euryarchaeota	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d1vdmg__d1ecjc1__1			Euryarchaeota	Proteobacteria	transferase activity, transferring glycosyl groups [GO:0016757]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	nucleoside metabolic process [GO:0009116]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	transferase activity, transferring glycosyl groups [GO:0016757]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]
d1vdpa__d2mecb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1vdpb__d3dmza___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1vdqa__d1qs9a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1vdra__d3srqx___1			Euryarchaeota	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d1vdta__d1c6ea___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1vdva6_d2w3sg3__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1vdvb2_d2y5cb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	mitochondrial matrix [GO:0005759]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; C21-steroid hormone biosynthetic process [GO:0006700]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	xanthine catabolic process [GO:0009115]	C21-steroid hormone biosynthetic process [GO:0006700]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	mitochondrial matrix [GO:0005759]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1vdvb3_d2w3sb1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1vdza3_d3j9ta4__1		Fungi	Euryarchaeota	Ascomycota	ATP binding [GO:0005524]; endonuclease activity [GO:0004519]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]		cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	ATP binding [GO:0005524]; endonuclease activity [GO:0004519]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]
d1ve6a1_d2xdwa1__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d1ve6b1_d1uooa1__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d1ve7a1_d1h2za1__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d1veca__d2fwra1__1	Metazoa		Chordata	Euryarchaeota	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]	cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]		cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]		ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]
d1vefa1_d1dkaa___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]		cytoplasm [GO:0005737]		pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1vefb__d3b1cc___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]		pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]
d1velb__d2xz0c___1		Viridiplantae	Actinobacteria	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	chloroplast [GO:0009507]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d1veld__d2inca___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1velf__d3a68q___1		Viridiplantae	Actinobacteria	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1vema2_d1kcka4__1			Firmicutes	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1vema2_d3ndza___1			Firmicutes	Firmicutes	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]			amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]
d1vena2_d2zx9a1__1			Firmicutes	Thermotogae	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	polysaccharide catabolic process [GO:0000272]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]		lysosome [GO:0005764]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-L-fucosidase activity [GO:0004560]
d1veoa2_d3amga___1			Firmicutes	Thermotogae	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	polysaccharide catabolic process [GO:0000272]	cellular glucan metabolic process [GO:0006073]		extracellular region [GO:0005576]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1vepa2_d3wdps1__1			Firmicutes	Euryarchaeota	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1veqb__d2fjcl___1			Actinobacteria	Spirochaetes	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1veqb__d4u3gg___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1veqc__d2zg8x___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1veqd__d5da5a1__1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]
d1veqe__d2c41b___1			Actinobacteria	Cyanobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1veqg__d2jd8x___1			Actinobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d1veqh__d4bmpa___1			Actinobacteria	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1veqi__d1xvfb___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1veqk__d2jd73___1			Actinobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d1vesb__d5niuc1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		
d1veva__d5kobc___1			Spirochaetes	Proteobacteria	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	translation [GO:0006412]			metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d1vewa2_d4l2cc2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1vewc1_d3ak1b1__1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1vewc2_d4br6d2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1vezb__d1bska___1			Spirochaetes	Proteobacteria	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]	ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]
d1vf2a2_d1z9hc1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	cytoplasm [GO:0005737]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]	glutathione transferase activity [GO:0004364]	electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]
d1vf2b2_d1pd221__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; glutathione metabolic process [GO:0006749]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693]	glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; prostaglandin metabolic process [GO:0006693]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1vf2b2_d4deja2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d1vf3b1_d1w4ve1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein disulfide oxidoreductase activity [GO:0015035]; protein-containing complex binding [GO:0044877]; cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cytoplasm [GO:0005737]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]	glutathione transferase activity [GO:0004364]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein-containing complex binding [GO:0044877]; protein disulfide oxidoreductase activity [GO:0015035]
d1vf4a1_d1z6na1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	metal ion binding [GO:0046872]	glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]	metal ion binding [GO:0046872]
d1vf4a2_d5ecle2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	glutathione transferase activity [GO:0004364]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1vfaa__d1fe8n1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1vfbb__d1rhhd2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1vfka4_d3do7b2__1		Metazoa		Chordata		centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]		centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]		chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d1vfkb6_d1e3za1__1				Firmicutes		extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1vfkb6_d3h54a2__1		Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]		carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d1vfla__d1a4ma___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]; adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; in utero embryonic development [GO:0001701]; inosine biosynthetic process [GO:0046103]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]	adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]	cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]	adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]
d1vfmb2_d1cdga3__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1vfmb3_d1jz1p5__1			Firmicutes		metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	
d1vfoa1_d3vtta___1			Firmicutes		metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1vfoa3_d4bs0b___1		Fungi	Firmicutes	Ascomycota	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	endo-1,4-beta-xylanase activity [GO:0031176]
d1vfob3_d4go9b1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d1vfpa3_d5avra4__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	integral component of membrane [GO:0016021]; ion channel regulator activity [GO:0099106]; ion transport [GO:0006811]; regulation of ion transport [GO:0043269]	calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	ion transport [GO:0006811]; regulation of ion transport [GO:0043269]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]	integral component of membrane [GO:0016021]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]	ion channel regulator activity [GO:0099106]
d1vfra__d1ooqa___1			Proteobacteria	Proteobacteria	oxidoreductase activity [GO:0016491]; bioluminescence [GO:0008218]	cytosol [GO:0005829]; membrane [GO:0016020]; 6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]; 2,4,6-trinitrotoluene catabolic process [GO:0046256]	bioluminescence [GO:0008218]	2,4,6-trinitrotoluene catabolic process [GO:0046256]		cytosol [GO:0005829]; membrane [GO:0016020]	oxidoreductase activity [GO:0016491]	6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]
d1vfua1_d1z0mc___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; fatty acid biosynthetic process [GO:0006633]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; regulation of catalytic activity [GO:0050790]	carbohydrate metabolic process [GO:0005975]	fatty acid biosynthetic process [GO:0006633]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; regulation of catalytic activity [GO:0050790]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]
d1vfua3_d1jyxa5__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1vfua3_d3vgba2__1			Firmicutes	Crenarchaeota	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]
d1vfub1_d4yeen1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]	carbohydrate metabolic process [GO:0005975]	fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]		apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]
d1vfub3_d3hg4a1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d1vg4b__d2q9zb___1		Fungi	Thermotogae	Ascomycota	transferase activity [GO:0016740]; isoprenoid biosynthetic process [GO:0008299]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	isoprenoid biosynthetic process [GO:0008299]	sesquiterpenoid biosynthetic process [GO:0016106]			transferase activity [GO:0016740]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]
d1vg6a__d4kuxb___1		Fungi	Thermotogae	Ascomycota	transferase activity [GO:0016740]; isoprenoid biosynthetic process [GO:0008299]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]	isoprenoid biosynthetic process [GO:0008299]				transferase activity [GO:0016740]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]
d1vgab__d4ymzb___1			Apicomplexa	Spirochaetes	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]		cytosol [GO:0005829]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1vgc.1_d3q76b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; phagocytic vesicle [GO:0045335]; secretory granule [GO:0030141]; specific granule lumen [GO:0035580]; transcriptional repressor complex [GO:0017053]; cytokine binding [GO:0019955]; endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; transcription corepressor activity [GO:0003714]; acute inflammatory response to antigenic stimulus [GO:0002438]; antimicrobial humoral response [GO:0019730]; biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0002812]; cellular calcium ion homeostasis [GO:0006874]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of chemotaxis [GO:0050922]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of fungus [GO:0070947]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of immune response [GO:0050778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; response to UV [GO:0009411]; response to yeast [GO:0001878]	digestion [GO:0007586]	acute inflammatory response to antigenic stimulus [GO:0002438]; antimicrobial humoral response [GO:0019730]; biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0002812]; cellular calcium ion homeostasis [GO:0006874]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of chemotaxis [GO:0050922]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of fungus [GO:0070947]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of immune response [GO:0050778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; response to UV [GO:0009411]; response to yeast [GO:0001878]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; phagocytic vesicle [GO:0045335]; secretory granule [GO:0030141]; specific granule lumen [GO:0035580]; transcriptional repressor complex [GO:0017053]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cytokine binding [GO:0019955]; endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; transcription corepressor activity [GO:0003714]
d1vgeh2_d4fqcl2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1vgel2_d5c9kf1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1vgkb__d5jorc1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1vgla__d2qkef___1			Cyanobacteria	Cyanobacteria	circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]	circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]	circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]	circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]				
d1vh0b1_d4jaka1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; rRNA (pseudouridine-N3-)-methyltransferase activity [GO:0070038]	cytoplasm [GO:0005737]; RNA binding [GO:0003723]; tRNA (cytosine-2'-O-)-methyltransferase activity [GO:0052666]; tRNA (uracil-2'-O-)-methyltransferase activity [GO:0052665]; wobble position cytosine ribose methylation [GO:0002131]; wobble position uridine ribose methylation [GO:0002132]		wobble position cytosine ribose methylation [GO:0002131]; wobble position uridine ribose methylation [GO:0002132]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	rRNA (pseudouridine-N3-)-methyltransferase activity [GO:0070038]	RNA binding [GO:0003723]; tRNA (cytosine-2'-O-)-methyltransferase activity [GO:0052666]; tRNA (uracil-2'-O-)-methyltransferase activity [GO:0052665]
d1vh7a__d5lnta___1		Viridiplantae	Thermotogae	Streptophyta	cytoplasm [GO:0005737]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]	histidine biosynthetic process [GO:0000105]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]	imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]	amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d1vh9a1_d2glpb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; thiolester hydrolase activity [GO:0016790]; enterobactin biosynthetic process [GO:0009239]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	enterobactin biosynthetic process [GO:0009239]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; thiolester hydrolase activity [GO:0016790]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d1vh9b1_d3r3db___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; thiolester hydrolase activity [GO:0016790]; enterobactin biosynthetic process [GO:0009239]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	enterobactin biosynthetic process [GO:0009239]		cytosol [GO:0005829]		1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; thiolester hydrolase activity [GO:0016790]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]
d1vhib__d1zzfa___1					host cell nucleus [GO:0042025]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of DNA replication [GO:0006275]; suppression by virus of host adaptive immune response [GO:0039504]; suppression by virus of host antigen processing and presentation [GO:0039588]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; viral latency [GO:0019042]	host cell nucleus [GO:0042025]; host cytoskeleton [GO:0044163]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	positive regulation of transcription, DNA-templated [GO:0045893]; regulation of DNA replication [GO:0006275]; suppression by virus of host adaptive immune response [GO:0039504]; suppression by virus of host antigen processing and presentation [GO:0039588]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; viral latency [GO:0019042]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]	host cell nucleus [GO:0042025]; host cytoskeleton [GO:0044163]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]
d1vhla1_d1ch8a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; dephospho-CoA kinase activity [GO:0004140]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; 'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	coenzyme A biosynthetic process [GO:0015937]	'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	ATP binding [GO:0005524]; dephospho-CoA kinase activity [GO:0004140]	adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d1vhlb1_d1d9xa2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; dephospho-CoA kinase activity [GO:0004140]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; excinuclease repair complex [GO:0009380]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; excinuclease ABC activity [GO:0009381]; nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432]	coenzyme A biosynthetic process [GO:0015937]	nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; excinuclease repair complex [GO:0009380]	ATP binding [GO:0005524]; dephospho-CoA kinase activity [GO:0004140]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; excinuclease ABC activity [GO:0009381]
d1vhma__d3nhqe2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]		L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d1vhma__d4e04a2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]	phosphorelay sensor kinase activity [GO:0000155]; detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]		L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]	phosphorelay sensor kinase activity [GO:0000155]
d1vhra__d5bzza1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; immunological synapse [GO:0001772]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cytoskeletal protein binding [GO:0008092]; MAP kinase phosphatase activity [GO:0033549]; phosphatase activity [GO:0016791]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; receptor tyrosine kinase binding [GO:0030971]; cellular response to epidermal growth factor stimulus [GO:0071364]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of focal adhesion assembly [GO:0051893]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; ubiquitin-specific protease binding [GO:1990381]; adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cellular response to epidermal growth factor stimulus [GO:0071364]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of focal adhesion assembly [GO:0051893]	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytosol [GO:0005829]; immunological synapse [GO:0001772]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	cytoskeletal protein binding [GO:0008092]; MAP kinase phosphatase activity [GO:0033549]; phosphatase activity [GO:0016791]; protein kinase binding [GO:0019901]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]	anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381]
d1vhrb__d2pq5a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; immunological synapse [GO:0001772]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cytoskeletal protein binding [GO:0008092]; MAP kinase phosphatase activity [GO:0033549]; phosphatase activity [GO:0016791]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; receptor tyrosine kinase binding [GO:0030971]; cellular response to epidermal growth factor stimulus [GO:0071364]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of focal adhesion assembly [GO:0051893]	phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dephosphorylation [GO:0016311]; meiotic cell cycle [GO:0051321]; protein dephosphorylation [GO:0006470]; spermatogenesis [GO:0007283]	cellular response to epidermal growth factor stimulus [GO:0071364]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of focal adhesion assembly [GO:0051893]	dephosphorylation [GO:0016311]; meiotic cell cycle [GO:0051321]; protein dephosphorylation [GO:0006470]; spermatogenesis [GO:0007283]	cytosol [GO:0005829]; immunological synapse [GO:0001772]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		cytoskeletal protein binding [GO:0008092]; MAP kinase phosphatase activity [GO:0033549]; phosphatase activity [GO:0016791]; protein kinase binding [GO:0019901]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]	phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1vhwe__d4x24b1__1			Proteobacteria	Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]	nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]			purine-nucleoside phosphorylase activity [GO:0004731]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d1vhzb__d2gt4b___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ADP-sugar diphosphatase activity [GO:0019144]; magnesium ion binding [GO:0000287]; nucleoside phosphate metabolic process [GO:0006753]; ribose phosphate metabolic process [GO:0019693]	GDP-glucosidase activity [GO:0047917]; GDP-mannose mannosyl hydrolase activity [GO:0008727]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; lipopolysaccharide biosynthetic process [GO:0009103]	nucleoside phosphate metabolic process [GO:0006753]; ribose phosphate metabolic process [GO:0019693]	lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]		ADP-sugar diphosphatase activity [GO:0019144]; magnesium ion binding [GO:0000287]	GDP-glucosidase activity [GO:0047917]; GDP-mannose mannosyl hydrolase activity [GO:0008727]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]
d1vi8g1_d2f3xb1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]; menaquinone biosynthetic process [GO:0009234]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; fatty acid biosynthetic process [GO:0006633]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of transcription, DNA-templated [GO:0045892]	menaquinone biosynthetic process [GO:0009234]	fatty acid biosynthetic process [GO:0006633]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]		1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1vica1_d1gq9b___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]
d1viga__d2anna1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]	intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; synapse [GO:0045202]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; chemical synaptic transmission [GO:0007268]; locomotory behavior [GO:0007626]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of cold-induced thermogenesis [GO:0120163]; regulation of RNA metabolic process [GO:0051252]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]	cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]	chemical synaptic transmission [GO:0007268]; locomotory behavior [GO:0007626]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of cold-induced thermogenesis [GO:0120163]; regulation of RNA metabolic process [GO:0051252]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]	cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	intracellular membrane-bounded organelle [GO:0043231]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; synapse [GO:0045202]	cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]	mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]
d1viha__d2cpqa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]	axon [GO:0030424]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic filopodium [GO:1902737]; dendritic spine [GO:0043197]; dendritic spine neck [GO:0044326]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; ribonucleoprotein granule [GO:0035770]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA strand annealing activity [GO:0033592]; translation regulator activity [GO:0045182]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; muscle organ development [GO:0007517]; negative regulation of translation [GO:0017148]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of filopodium assembly [GO:0051489]; regulation of mRNA stability [GO:0043488]	cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]	apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; muscle organ development [GO:0007517]; negative regulation of translation [GO:0017148]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of filopodium assembly [GO:0051489]; regulation of mRNA stability [GO:0043488]	cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	axon [GO:0030424]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic filopodium [GO:1902737]; dendritic spine [GO:0043197]; dendritic spine neck [GO:0044326]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; ribonucleoprotein granule [GO:0035770]	cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]	mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA strand annealing activity [GO:0033592]; translation regulator activity [GO:0045182]
d1vija__d2g1na___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d1vika__d2qp8b___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d1vikb__d5p5ma___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1vipa__d1fe5a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1visa1_d1e3pa4__1			Euryarchaeota	Actinobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; polyribonucleotide nucleotidyltransferase activity [GO:0004654]; RNA binding [GO:0003723]; mRNA catabolic process [GO:0006402]; RNA processing [GO:0006396]	isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]	mRNA catabolic process [GO:0006402]; RNA processing [GO:0006396]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]	magnesium ion binding [GO:0000287]; polyribonucleotide nucleotidyltransferase activity [GO:0004654]; RNA binding [GO:0003723]
d1viwa1_d1ud2a1__1	Metazoa		Arthropoda	Firmicutes	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]			alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1vj0a2_d3d5qb2__1		Metazoa	Thermotogae	Chordata	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d1vj0a2_d5vl0c2__1		Metazoa	Thermotogae	Chordata	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1vj0b2_d1lluh2__1			Thermotogae	Proteobacteria	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]				cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; nucleotide binding [GO:0000166]; zinc ion binding [GO:0008270]
d1vj0c2_d4i9ne1__1		Metazoa	Thermotogae	Chordata	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	L-lactate dehydrogenase activity [GO:0004459]
d1vj3a__d3jwfa1__1	Fungi		Ascomycota	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d1vjca__d5bt8d___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; phosphorylation [GO:0016310]; positive regulation of oxidative phosphorylation [GO:1903862]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; phosphorylation [GO:0016310]; positive regulation of oxidative phosphorylation [GO:1903862]	glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]	ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]
d1vjja5_d5jhla2__1						host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1vjjb5_d1m42a___1				Proteobacteria		periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; copper ion transport [GO:0006825]; response to copper ion [GO:0046688]		copper ion transport [GO:0006825]; response to copper ion [GO:0046688]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]
d1vjjb6_d1rlla2__1												
d1vkaa1_d5a36b1__1	Metazoa	Metazoa	Chordata	Chordata	cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; cell division [GO:0051301]; cell migration [GO:0016477]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of cell migration [GO:0030335]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; pseudopodium [GO:0031143]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]; actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	cell division [GO:0051301]; cell migration [GO:0016477]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of cell migration [GO:0030335]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; pseudopodium [GO:0031143]; Z disc [GO:0030018]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]
d1vkca__d1xo4a___1			Euryarchaeota		N-acetyltransferase activity [GO:0008080]						N-acetyltransferase activity [GO:0008080]	
d1vkcb__d2yncb1__1			Euryarchaeota	Apicomplexa	N-acetyltransferase activity [GO:0008080]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]		N-terminal protein myristoylation [GO:0006499]			N-acetyltransferase activity [GO:0008080]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d1vkia__d2z0xa___1			Proteobacteria	Deinococcus-Thermus	aminoacyl-tRNA editing activity [GO:0002161]	aminoacyl-tRNA editing activity [GO:0002161]; translation [GO:0006412]		translation [GO:0006412]			aminoacyl-tRNA editing activity [GO:0002161]	aminoacyl-tRNA editing activity [GO:0002161]
d1vkib__d2cx5a___1			Proteobacteria	Deinococcus-Thermus	aminoacyl-tRNA editing activity [GO:0002161]	aminoacyl-tRNA editing activity [GO:0002161]; translation [GO:0006412]		translation [GO:0006412]			aminoacyl-tRNA editing activity [GO:0002161]	aminoacyl-tRNA editing activity [GO:0002161]
d1vkla3_d3rsma3__1	Metazoa		Chordata	Proteobacteria	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	glucose metabolic process [GO:0006006]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	sarcoplasmic reticulum [GO:0016529]		magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]
d1vklb2_d5epcb1__1	Metazoa	Metazoa	Chordata	Chordata	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	glucose metabolic process [GO:0006006]	galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	sarcoplasmic reticulum [GO:0016529]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1vklb4_d1kfqb4__1	Metazoa		Chordata	Ciliophora	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	glucose metabolic process [GO:0006006]	galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	sarcoplasmic reticulum [GO:0016529]	cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d1vklb4_d4mrqa4__1	Metazoa		Chordata	Proteobacteria	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	glucose metabolic process [GO:0006006]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	sarcoplasmic reticulum [GO:0016529]		magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]
d1vkoa2_d3cmcr2__1				Firmicutes		cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1vkra__d5dled___1			Proteobacteria	Spirochaetes	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity [GO:0022872]; protein-phosphocysteine-mannitol phosphotransferase system transporter activity [GO:0090565]; mannitol transport [GO:0015797]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]; carbohydrate:proton symporter activity [GO:0005351]; protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity [GO:0022877]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	mannitol transport [GO:0015797]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity [GO:0022872]; protein-phosphocysteine-mannitol phosphotransferase system transporter activity [GO:0090565]	carbohydrate:proton symporter activity [GO:0005351]; protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity [GO:0022877]
d1vkxa1_d1leib1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1vkxb2_d2qxaa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]		apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	
d1vl1a__d1fqob___1			Thermotogae	Proteobacteria	6-phosphogluconolactonase activity [GO:0017057]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, oxidative branch [GO:0009051]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, oxidative branch [GO:0009051]	carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	6-phosphogluconolactonase activity [GO:0017057]	glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]
d1vl1a__d4eu4a2__1			Thermotogae	Proteobacteria	6-phosphogluconolactonase activity [GO:0017057]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, oxidative branch [GO:0009051]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, oxidative branch [GO:0009051]	acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]			6-phosphogluconolactonase activity [GO:0017057]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d1vl9a__d2h8ib___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]
d1vlba1_d2w3ra2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1vlba2_d1dgja2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1vldm1_d3iasl4__1				Deinococcus-Thermus		plasma membrane [GO:0005886]; quinone binding [GO:0048038]				plasma membrane [GO:0005886]		quinone binding [GO:0048038]
d1vldo1_d5ftja1__1		Metazoa		Chordata		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1vldo2_d1g8jc2__1				Proteobacteria		3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]						3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]
d1vldu1_d4kodl1__1		Metazoa		Chordata		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1vldw1_d1ogyg1__1				Proteobacteria		periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]		anaerobic respiration [GO:0009061]		periplasmic space [GO:0042597]		metal ion binding [GO:0046872]
d1vlen2_d6fd1a___1				Proteobacteria		3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1vles1_d3iasc4__1				Deinococcus-Thermus		plasma membrane [GO:0005886]; quinone binding [GO:0048038]				plasma membrane [GO:0005886]		quinone binding [GO:0048038]
d1vles2_d1e60a2__1				Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]
d1vleu1_d3hu2b1__1		Metazoa		Chordata		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1vlev2_d1q16b___1				Proteobacteria		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]
d1vlfm1_d1e18a1__1				Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]
d1vlfn1_d3rkpb3__1				Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]				cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]		metal ion binding [GO:0046872]
d1vlfq1_d4kode1__1		Metazoa		Chordata		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1vlft1_d3rkpb1__1				Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]				cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]		metal ion binding [GO:0046872]
d1vlfw1_d1ogyi1__1				Proteobacteria		periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]		anaerobic respiration [GO:0009061]		periplasmic space [GO:0042597]		metal ion binding [GO:0046872]
d1vlfw1_d3hu2f1__1		Metazoa		Chordata		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1vlgb__d4togc___1			Thermotogae	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1vlgc__d3pzab1__1			Thermotogae	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1vlgd__d4u3gj___1			Thermotogae	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1vlgf__d5jkme___1		Metazoa	Thermotogae	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1vlgg__d3is8t___1			Thermotogae	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1vlgh__d1nnqa1__1			Thermotogae	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1vlhf__d1k4ma___1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; 'de novo' NAD biosynthetic process from aspartate [GO:0034628]; NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]	coenzyme A biosynthetic process [GO:0015937]	'de novo' NAD biosynthetic process from aspartate [GO:0034628]; NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]
d1vlhf__d2cfob1__1			Thermotogae	Cyanobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	coenzyme A biosynthetic process [GO:0015937]	glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1vlia1_d2amea___1		Metazoa	Firmicutes	Chordata	catalytic activity [GO:0003824]; carbohydrate biosynthetic process [GO:0016051]	extracellular region [GO:0005576]	carbohydrate biosynthetic process [GO:0016051]			extracellular region [GO:0005576]	catalytic activity [GO:0003824]	
d1vlla__d5wqpb1__1			Euryarchaeota	Proteobacteria	alanine dehydrogenase activity [GO:0000286]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]; alanine metabolic process [GO:0006522]	carbonyl reductase (NADPH) activity [GO:0004090]	alanine metabolic process [GO:0006522]				alanine dehydrogenase activity [GO:0000286]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]	carbonyl reductase (NADPH) activity [GO:0004090]
d1vlnd__d5duwc___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]		cell adhesion [GO:0007155]		collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d1vlne__d2nyya3__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1vlng__d4atfa___1	Viridiplantae		Streptophyta	Bacteroidetes	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cell outer membrane [GO:0009279]; beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		cell outer membrane [GO:0009279]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]
d1vlrb1_d3bl7b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]; cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]; cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]	exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]
d1vlta__d1vlsa___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; transmembrane signaling receptor activity [GO:0004888]; chemotaxis [GO:0006935]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; transmembrane signaling receptor activity [GO:0004888]; chemotaxis [GO:0006935]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]	integral component of plasma membrane [GO:0005887]	transmembrane signaling receptor activity [GO:0004888]	transmembrane signaling receptor activity [GO:0004888]
d1vlwb1_d3eb2b1__1			Thermotogae	Proteobacteria	lyase activity [GO:0016829]	lyase activity [GO:0016829]					lyase activity [GO:0016829]	lyase activity [GO:0016829]
d1vlxa__d1fa4a___1			Proteobacteria	Cyanobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	thylakoid membrane [GO:0042651]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1vlxb__d5b7ea1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d1vlxd__d4q8ba2__1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	oxidation-reduction process [GO:0055114]	sporulation resulting in formation of a cellular spore [GO:0030435]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1vm6a2_d1ofgb2__1			Thermotogae	Proteobacteria	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	periplasmic space [GO:0042597]; glucose-fructose oxidoreductase activity [GO:0047061]; sorbitol biosynthetic process [GO:0006061]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	sorbitol biosynthetic process [GO:0006061]	cytosol [GO:0005829]	periplasmic space [GO:0042597]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]	glucose-fructose oxidoreductase activity [GO:0047061]
d1vm6c2_d1cerd2__1			Thermotogae	Deinococcus-Thermus	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1vm6c2_d1u1ia2__1			Thermotogae	Euryarchaeota	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	integral component of membrane [GO:0016021]; inositol-3-phosphate synthase activity [GO:0004512]; nucleotide binding [GO:0000166]; inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	cytosol [GO:0005829]	integral component of membrane [GO:0016021]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]	inositol-3-phosphate synthase activity [GO:0004512]; nucleotide binding [GO:0000166]
d1vm7a__d2pkfb1__1			Thermotogae	Actinobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]	plasma membrane [GO:0005886]; adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; carbohydrate kinase activity [GO:0019200]; dGTP binding [GO:0032567]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]	D-ribose catabolic process [GO:0019303]	AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]	cytosol [GO:0005829]	plasma membrane [GO:0005886]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]	adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; carbohydrate kinase activity [GO:0019200]; dGTP binding [GO:0032567]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d1vmaa2_d1p2va___1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; signal recognition particle binding [GO:0005047]; cell division [GO:0051301]; protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell division [GO:0051301]; protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; signal recognition particle binding [GO:0005047]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1vmab1_d1ftsa1__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; signal recognition particle binding [GO:0005047]; cell division [GO:0051301]; protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; signal recognition particle binding [GO:0005047]; protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cell division [GO:0051301]; protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytoplasm [GO:0005737]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; signal recognition particle binding [GO:0005047]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; signal recognition particle binding [GO:0005047]
d1vmab2_d3oe7e2__1		Fungi	Thermotogae	Ascomycota	cytoplasm [GO:0005737]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; signal recognition particle binding [GO:0005047]; cell division [GO:0051301]; protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cell division [GO:0051301]; protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	ATP synthesis coupled proton transport [GO:0015986]	cytoplasm [GO:0005737]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; signal recognition particle binding [GO:0005047]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1vmba__d2qbhf1__1			Thermotogae		cytosolic small ribosomal subunit [GO:0022627]; small ribosomal subunit rRNA binding [GO:0070181]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		cytosolic small ribosomal subunit [GO:0022627]		small ribosomal subunit rRNA binding [GO:0070181]; structural constituent of ribosome [GO:0003735]	
d1vmda1_d1cs0e2__1			Thermotogae	Proteobacteria	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1vmfa1_d1vpha1__1			Firmicutes	Crenarchaeota								
d1vmha__d1vphd1__1			Firmicutes	Crenarchaeota								
d1vmha__d2p6hb___1			Firmicutes	Crenarchaeota								
d1vnea__d1vnsa___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]
d1vnfa__d1qi9b___1	Fungi		Ascomycota		extracellular region [GO:0005576]; chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]			extracellular region [GO:0005576]		chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1vnfa__d1vnca___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]
d1vola2_d1d3ub2__1	Viridiplantae		Streptophyta	Euryarchaeota	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]		DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1volb2_d3ocia1__1	Viridiplantae	Fungi	Streptophyta	Microsporidia	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]; DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]		DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]
d1vp2b__d1v7ra___1			Thermotogae	Euryarchaeota	cytosol [GO:0005829]; metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	cytosol [GO:0005829]		metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]
d1vp6a__d4a2uh1__1			Proteobacteria	Actinobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]		negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1vpaa1_d1g1la___1			Thermotogae	Proteobacteria	cytosol [GO:0005829]; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [GO:0050518]; cytidylyltransferase activity [GO:0070567]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]		2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [GO:0050518]; cytidylyltransferase activity [GO:0070567]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1vpaa1_d1h7ga___1			Thermotogae	Proteobacteria	cytosol [GO:0005829]; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [GO:0050518]; cytidylyltransferase activity [GO:0070567]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [GO:0050518]; cytidylyltransferase activity [GO:0070567]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]
d1vphd1_d2p6ha___1			Crenarchaeota	Crenarchaeota								
d1vpia__d3osha___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; host cell postsynaptic membrane [GO:0035792]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; host cell postsynaptic membrane [GO:0035792]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]
d1vpka2_d1jqla3__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1vpka3_d1ge8a2__1			Thermotogae	Euryarchaeota	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]		3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d1vpla__d2hlda2__1		Fungi	Thermotogae	Ascomycota	ATP binding [GO:0005524]; ATPase activity [GO:0016887]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]		ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1vpnc__d4poqi___1					host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]	virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]	host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]	structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1vpnd__d4u62e___1					host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]; structural molecule activity [GO:0005198]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]	virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]	host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1vpoh2_d1c5bl1__1												
d1vpol1_d5n2fa1__1		Metazoa		Chordata		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		
d1vpxc1_d3pula___1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1vpxk1_d1ewdb___1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]	I band [GO:0031674]; M band [GO:0031430]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	fructose-bisphosphate aldolase activity [GO:0004332]
d1vpxk1_d1gjpa___1		Fungi	Thermotogae	Ascomycota	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]
d1vpxo1_d3mmtb1__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]		aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	fructose-bisphosphate aldolase activity [GO:0004332]
d1vpxs1_d4i7ud1__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]; pyruvate metabolic process [GO:0006090]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]; pyruvate metabolic process [GO:0006090]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1vq3c1_d4mgha1__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]
d1vq3d1_d3ugja1__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]
d1vq4n1_d3d5ak1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vq4p1_d1m1kq___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1vq5b1_d1ktva1__1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]	translation [GO:0006412]	translational elongation [GO:0006414]	ribosome [GO:0005840]	cytoplasm [GO:0005737]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]
d1vq5e1_d1vs6g2__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vq5f1_d2qi2a3__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; RNA surveillance [GO:0071025]	translation [GO:0006412]	nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; RNA surveillance [GO:0071025]	ribosome [GO:0005840]	cytoplasm [GO:0005737]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d1vq6k1_d1k73l___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1vq6n1_d2gyam1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vq6o1_d2i2tl1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vq7a1_d2qp1c1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vq7k1_d2vhnk1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vq8b1_d4m0la2__1			Euryarchaeota	Crenarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	translation [GO:0006412]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	ribosome [GO:0005840]	cytosol [GO:0005829]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1vq8p1_d1q82q___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1vq9b1_d1eloa1__1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	translation [GO:0006412]		ribosome [GO:0005840]	cytoplasm [GO:0005737]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1vq9f1_d3mcab2__1		Fungi	Euryarchaeota	Ascomycota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Dom34-Hbs1 complex [GO:1990533]; nucleus [GO:0005634]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; ribosome binding [GO:0043022]; translation release factor activity [GO:0003747]; cell division [GO:0051301]; cytoplasmic translational termination [GO:0002184]; endoplasmic reticulum unfolded protein response [GO:0030968]; meiotic cell cycle [GO:0051321]; negative regulation of G0 to G1 transition [GO:0070317]; nonfunctional rRNA decay [GO:0070651]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; ribosome disassembly [GO:0032790]; RNA surveillance [GO:0071025]	translation [GO:0006412]	cell division [GO:0051301]; cytoplasmic translational termination [GO:0002184]; endoplasmic reticulum unfolded protein response [GO:0030968]; meiotic cell cycle [GO:0051321]; negative regulation of G0 to G1 transition [GO:0070317]; nonfunctional rRNA decay [GO:0070651]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; ribosome disassembly [GO:0032790]; RNA surveillance [GO:0071025]	ribosome [GO:0005840]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Dom34-Hbs1 complex [GO:1990533]; nucleus [GO:0005634]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; ribosome binding [GO:0043022]; translation release factor activity [GO:0003747]
d1vqba__d2uubl1__1				Deinococcus-Thermus	single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; rolling circle single-stranded viral DNA replication [GO:0039684]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	DNA replication [GO:0006260]; rolling circle single-stranded viral DNA replication [GO:0039684]	translation [GO:0006412]		ribosome [GO:0005840]	single-stranded DNA binding [GO:0003697]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1vqia__d1yhab___1					single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; rolling circle single-stranded viral DNA replication [GO:0039684]	single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; rolling circle single-stranded viral DNA replication [GO:0039684]	DNA replication [GO:0006260]; rolling circle single-stranded viral DNA replication [GO:0039684]	DNA replication [GO:0006260]; rolling circle single-stranded viral DNA replication [GO:0039684]			single-stranded DNA binding [GO:0003697]	single-stranded DNA binding [GO:0003697]
d1vqka1_d2qaoc1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vqlb1_d3dllb1__1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	cytosolic large ribosomal subunit [GO:0022625]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d1vqmb1_d4pc2b2__1			Euryarchaeota	Proteobacteria	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; translation elongation factor activity [GO:0003746]	translation [GO:0006412]		ribosome [GO:0005840]	cytoplasm [GO:0005737]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	translation elongation factor activity [GO:0003746]
d1vqmc1_d2j01f1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vqmn1_d3df1k1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vqnj1_d2hgqm1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vqnn1_d2i2to1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vqob1_d2qbad1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vqob1_d4q7jb2__1			Euryarchaeota	Proteobacteria	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	translation [GO:0006412]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	ribosome [GO:0005840]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1vqof1_d2hvyd1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; rRNA processing [GO:0006364]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	translation [GO:0006412]	rRNA processing [GO:0006364]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	ribosome [GO:0005840]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1vqpb1_d3df4d1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vqpj1_d3dllg1__1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	cytosolic large ribosomal subunit [GO:0022625]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d1vqps1_d2qbet1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1vqqa1_d1uuvb___1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; response to antibiotic [GO:0046677]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	response to antibiotic [GO:0046677]	aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]		penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]	dioxygenase activity [GO:0051213]
d1vqwb2_d1h7xd3__1	Fungi	Metazoa	Ascomycota	Chordata	endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; monooxygenase activity [GO:0004497]; N,N-dimethylaniline monooxygenase activity [GO:0004499]; NADP binding [GO:0050661]; protein folding in endoplasmic reticulum [GO:0034975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	protein folding in endoplasmic reticulum [GO:0034975]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	flavin adenine dinucleotide binding [GO:0050660]; monooxygenase activity [GO:0004497]; N,N-dimethylaniline monooxygenase activity [GO:0004499]; NADP binding [GO:0050661]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d1vqza1_d5ibya2__1			Firmicutes	Firmicutes	ATP binding [GO:0005524]; ligase activity [GO:0016874]; protein lipoylation [GO:0009249]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; protein lipoylation [GO:0009249]	protein lipoylation [GO:0009249]	protein lipoylation [GO:0009249]			ATP binding [GO:0005524]; ligase activity [GO:0016874]	ATP binding [GO:0005524]; ligase activity [GO:0016874]
d1vr4d__d1ybba___1			Firmicutes									
d1vrcb__d3iprb___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]; enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]	integral component of membrane [GO:0016021]	enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]	metal ion binding [GO:0046872]
d1vrcc__d3lnwc___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]; enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	cytoplasm [GO:0005737]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]	cytoplasm [GO:0005737]	enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]	transferase activity [GO:0016740]
d1vrea__d4h0mk___1	Metazoa		Annelida	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1vrfa__d3arla___1	Metazoa	Metazoa	Annelida	Arthropoda	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1vrfa__d3b75c___1	Metazoa	Metazoa	Annelida	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1vrla1_d1yqla1__1		Metazoa	Firmicutes	Chordata	4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]		mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]
d1vrpb1_d3m10a1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d1vrpb2_d1f52i2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	phosphocreatine biosynthetic process [GO:0046314]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d1vrsd__d3a5wh___1			Proteobacteria	Crenarchaeota	cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]; electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]	cell [GO:0005623]; cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1vrse__d4l0ua___1			Proteobacteria	Apicomplexa	cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]; electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]	cell [GO:0005623]	electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peroxiredoxin activity [GO:0051920]
d1vrsf__d1syrc___1			Proteobacteria	Apicomplexa	cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]; electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]	cell [GO:0005623]; cytosol [GO:0005829]	electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	protein disulfide oxidoreductase activity [GO:0015035]
d1vrxb__d3f55b___1			Actinobacteria		cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]				cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	
d1vs5g1_d2v48g1__1												
d1vs5l1_d4a76c___1		Metazoa		Chordata		nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]						nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]
d1vs5q1_d1ph4a1__1				Ciliophora		nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]		telomere capping [GO:0016233]		nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]		protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1vs631_d2zjr31__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d1vs6d1_d1yjnb1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1vs6d1_d4pgoa___1				Euryarchaeota								
d1vs6p1_d2v47t1__1												
d1vs6v1_d2zjrs1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d1vs6w1_d2vhnw1__1												
d1vs7c2_d1i97c2__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1vs7f1_d1cqnb___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1vs7g1_d2f4vg1__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1vs7i1_d2c38d1__1				Crenarchaeota		cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]		rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]
d1vs8g2_d1n8rg1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1vs8i2_d3cjsc1__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; protein methyltransferase activity [GO:0008276]				cytoplasm [GO:0005737]		protein methyltransferase activity [GO:0008276]
d1vs8o1_d2uxdk1__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1vsac1_d3mqkc___1				Euryarchaeota		snoRNA binding [GO:0030515]; pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]		pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]				snoRNA binding [GO:0030515]
d1vsal1_d2qbcn1__1												
d1vsam1_d2z4mk1__1												
d1vsar1_d1kqsl___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1vsar1_d2i2tt1__1												
d1vsau1_d2zjrt1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d1vsca1_d3gsqa2__1	Metazoa	Metazoa	Chordata	Chordata	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell chemotaxis [GO:0060326]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1vsca2_d2f74d1__1	Metazoa	Metazoa	Chordata	Chordata	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell chemotaxis [GO:0060326]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1vscb1_d5mp2c1__1	Metazoa		Chordata	Proteobacteria	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; type II protein secretion system complex [GO:0015627]; identical protein binding [GO:0042802]; protein secretion by the type II secretion system [GO:0015628]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell chemotaxis [GO:0060326]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	protein secretion by the type II secretion system [GO:0015628]	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; type II protein secretion system complex [GO:0015627]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]	identical protein binding [GO:0042802]
d1vscb2_d1koaa1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	A band [GO:0031672]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; structural constituent of muscle [GO:0008307]; adult locomotory behavior [GO:0008344]; behavioral response to nicotine [GO:0035095]; muscle contraction [GO:0006936]; negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of locomotion [GO:0040017]; positive regulation of sarcomere organization [GO:0060298]; positive regulation of striated muscle contraction [GO:0045989]; sarcomere organization [GO:0045214]; striated muscle myosin thick filament assembly [GO:0071688]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell chemotaxis [GO:0060326]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	adult locomotory behavior [GO:0008344]; behavioral response to nicotine [GO:0035095]; muscle contraction [GO:0006936]; negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of locomotion [GO:0040017]; positive regulation of sarcomere organization [GO:0060298]; positive regulation of striated muscle contraction [GO:0045989]; sarcomere organization [GO:0045214]; striated muscle myosin thick filament assembly [GO:0071688]	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]	A band [GO:0031672]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; structural constituent of muscle [GO:0008307]
d1vsfa__d1fkpa1__1					virion [GO:0019012]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; retroviral integrase activity [GO:0044823]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	virion [GO:0019012]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; retroviral integrase activity [GO:0044823]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1vsla__d1hpza1__1					virion [GO:0019012]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; retroviral integrase activity [GO:0044823]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	virion [GO:0019012]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; retroviral integrase activity [GO:0044823]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1vsma__d1jlca1__1					virion [GO:0019012]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; retroviral integrase activity [GO:0044823]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	virion [GO:0019012]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; retroviral integrase activity [GO:0044823]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1vspc1_d4m53a2__1				Crenarchaeota		cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1vspf2_d1njig2__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1vspp1_d2z4lr1__1												
d1vsqc__d1nrza___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]; glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]	cytoplasm [GO:0005737]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]
d1vsy2__d1p4va___1				Bacteroidetes		periplasmic space [GO:0042597]; N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity [GO:0003948]; peptidase activity [GO:0008233]				periplasmic space [GO:0042597]		N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity [GO:0003948]; peptidase activity [GO:0008233]
d1vsyc__d4qwgs___1		Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1vsyd__d4qz4k___1		Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1vsyq__d5l62s___1		Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1vsyv1_d2f16p___1		Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1vtle1_d1tbpb1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]
d1vtle1_d3eika2__1	Viridiplantae	Fungi	Streptophyta	Microsporidia	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]; DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]		DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]
d1vtle2_d1c9br1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1vtlf1_d3cwsb2__1	Viridiplantae		Streptophyta	Proteobacteria	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1vtlf2_d1vtlf1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d1vtmp__d2tmvp___1					helical viral capsid [GO:0019029]; structural molecule activity [GO:0005198]	helical viral capsid [GO:0019029]; structural molecule activity [GO:0005198]			helical viral capsid [GO:0019029]	helical viral capsid [GO:0019029]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1vtnc__d1d5va___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein domain specific binding [GO:0019904]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; cellular glucose homeostasis [GO:0001678]; cellular response to starvation [GO:0009267]; chromatin organization [GO:0006325]; multicellular organism development [GO:0007275]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; anatomical structure morphogenesis [GO:0009653]; artery morphogenesis [GO:0048844]; blood vessel remodeling [GO:0001974]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye development [GO:0043010]; cardiac muscle cell proliferation [GO:0060038]; cell differentiation [GO:0030154]; collagen fibril organization [GO:0030199]; embryonic heart tube development [GO:0035050]; embryonic viscerocranium morphogenesis [GO:0048703]; glomerular endothelium development [GO:0072011]; glomerular mesangial cell development [GO:0072144]; glomerular visceral epithelial cell differentiation [GO:0072112]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; lymphangiogenesis [GO:0001946]; mesoderm development [GO:0007498]; metanephros development [GO:0001656]; negative regulation of apoptotic process involved in outflow tract morphogenesis [GO:1902257]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell development [GO:0014032]; Notch signaling pathway [GO:0007219]; ossification [GO:0001503]; paraxial mesodermal cell fate commitment [GO:0048343]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular wound healing [GO:0035470]; regulation of blood vessel diameter [GO:0097746]; regulation of organ growth [GO:0046620]; regulation of transcription by RNA polymerase II [GO:0006357]; response to hormone [GO:0009725]; somitogenesis [GO:0001756]; ureteric bud development [GO:0001657]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; cellular glucose homeostasis [GO:0001678]; cellular response to starvation [GO:0009267]; chromatin organization [GO:0006325]; multicellular organism development [GO:0007275]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]	anatomical structure morphogenesis [GO:0009653]; artery morphogenesis [GO:0048844]; blood vessel remodeling [GO:0001974]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye development [GO:0043010]; cardiac muscle cell proliferation [GO:0060038]; cell differentiation [GO:0030154]; collagen fibril organization [GO:0030199]; embryonic heart tube development [GO:0035050]; embryonic viscerocranium morphogenesis [GO:0048703]; glomerular endothelium development [GO:0072011]; glomerular mesangial cell development [GO:0072144]; glomerular visceral epithelial cell differentiation [GO:0072112]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; lymphangiogenesis [GO:0001946]; mesoderm development [GO:0007498]; metanephros development [GO:0001656]; negative regulation of apoptotic process involved in outflow tract morphogenesis [GO:1902257]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell development [GO:0014032]; Notch signaling pathway [GO:0007219]; ossification [GO:0001503]; paraxial mesodermal cell fate commitment [GO:0048343]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular wound healing [GO:0035470]; regulation of blood vessel diameter [GO:0097746]; regulation of organ growth [GO:0046620]; regulation of transcription by RNA polymerase II [GO:0006357]; response to hormone [GO:0009725]; somitogenesis [GO:0001756]; ureteric bud development [GO:0001657]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein domain specific binding [GO:0019904]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]
d1vtoa2_d3oc3c2__1	Viridiplantae	Fungi	Streptophyta	Microsporidia	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]		nucleus [GO:0005634]; transcription factor complex [GO:0005667]		DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]
d1vtob1_d3eikb1__1	Viridiplantae	Fungi	Streptophyta	Microsporidia	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]; DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]		DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]
d1vtz0__d4oq9a___1						viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d1vtzn__d4niam___1						viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d1vu0g__d3ra9a___1						viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d1vu0m__d3kicl___1						viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d1vu0x__d1c8fa___1						host cell nucleus [GO:0042025]; T=1 icosahedral viral capsid [GO:0039615]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; viral penetration into host nucleus [GO:0075732]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; viral penetration into host nucleus [GO:0075732]; virion attachment to host cell [GO:0019062]		host cell nucleus [GO:0042025]; T=1 icosahedral viral capsid [GO:0039615]		metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d1vu1w__d1gff2___1						host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]; DNA binding [GO:0003677]				host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]		DNA binding [GO:0003677]
d1vu1w__d3kics___1						viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d1vu1x__d3kiej___1						viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d1vu24__d1i5lk___1				Euryarchaeota								
d1vu2a__d4j6ya___1				Proteobacteria		cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]		pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]		cytosol [GO:0005829]		RNA binding [GO:0003723]
d1vu2f__d1jrig1__1				Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]		
d1vu2g__d1jria1__1				Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]		
d1vu2i__d4m78c___1		Fungi		Ascomycota		Lsm1-7-Pat1 complex [GO:1990726]; nucleolus [GO:0005730]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]		maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]		Lsm1-7-Pat1 complex [GO:1990726]; nucleolus [GO:0005730]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]		RNA binding [GO:0003723]
d1vu2k__d4f77w___1												
d1vu2q__d1jrik___1				Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]		
d1vu3k__d1i5lc___1				Euryarchaeota								
d1vu3o__d1n9sk___1		Fungi		Ascomycota		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]
d1vu3s__d1n9sf___1		Fungi		Ascomycota		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		catalytic step 2 spliceosome [GO:0071013]; small nucleolar ribonucleoprotein complex [GO:0005732]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]
d1vu3t__d1lnxb___1				Crenarchaeota								
d1vu3y__d1jrij___1				Euryarchaeota		small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]		mRNA splicing, via spliceosome [GO:0000398]		small nucleolar ribonucleoprotein complex [GO:0005732]		
d1vubc__d4hkeb1__1			Proteobacteria	Firmicutes	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity [GO:0008657]; plasmid maintenance [GO:0006276]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]	plasmid maintenance [GO:0006276]				DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity [GO:0008657]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]
d1vwad__d1swrd___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1vwbb__d4yvbb___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1vweb__d3szie___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1vwid__d3szij1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1vwjd__d1avda___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]; antibacterial humoral response [GO:0019731]		antibacterial humoral response [GO:0019731]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1vwmb__d1swua___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1vwta__d2gkma___1	Metazoa		Chordata	Actinobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1vwtc__d4mqjf1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1vxba__d4mqkh___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1vxca__d4lmxb___1	Metazoa		Chordata	Cryptophyta	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	chloroplast [GO:0009507]; phycobilisome [GO:0030089]; protein-chromophore linkage [GO:0018298]		protein-chromophore linkage [GO:0018298]		chloroplast [GO:0009507]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1vxra__d4n8da2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	acetylcholinesterase activity [GO:0003990]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1vybb__d5ewta___1	Metazoa		Chordata	Crenarchaeota	metal ion binding [GO:0046872]; RNA-directed DNA polymerase activity [GO:0003964]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197]	nuclease activity [GO:0004518]; DNA repair [GO:0006281]	DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197]	DNA repair [GO:0006281]			metal ion binding [GO:0046872]; RNA-directed DNA polymerase activity [GO:0003964]; type II site-specific deoxyribonuclease activity [GO:0009036]	nuclease activity [GO:0004518]
d1vyda__d1ql3b___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	photosynthesis [GO:0015979]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1vydb__d5cigd___1		Fungi	Proteobacteria	Ascomycota	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	photosynthesis [GO:0015979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1vyhb1_d1dexa___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; 1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; platelet-activating factor acetyltransferase activity [GO:0047179]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; brain development [GO:0007420]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; neutrophil degranulation [GO:0043312]; positive regulation of macroautophagy [GO:0016239]; spermatogenesis [GO:0007283]	hydrolase activity [GO:0016787]	brain development [GO:0007420]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; neutrophil degranulation [GO:0043312]; positive regulation of macroautophagy [GO:0016239]; spermatogenesis [GO:0007283]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]		1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; platelet-activating factor acetyltransferase activity [GO:0047179]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	hydrolase activity [GO:0016787]
d1vyhf1_d4jj4a___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; 1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; platelet-activating factor acetyltransferase activity [GO:0047179]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; brain development [GO:0007420]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; neutrophil degranulation [GO:0043312]; positive regulation of macroautophagy [GO:0016239]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; xylan catabolic process [GO:0045493]	brain development [GO:0007420]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; neutrophil degranulation [GO:0043312]; positive regulation of macroautophagy [GO:0016239]; spermatogenesis [GO:0007283]	xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; platelet-activating factor acetyltransferase activity [GO:0047179]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	acetylxylan esterase activity [GO:0046555]
d1vyhn1_d5bn1b___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; 1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; platelet-activating factor acetyltransferase activity [GO:0047179]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; brain development [GO:0007420]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; neutrophil degranulation [GO:0043312]; positive regulation of macroautophagy [GO:0016239]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; xylan catabolic process [GO:0045493]	brain development [GO:0007420]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; neutrophil degranulation [GO:0043312]; positive regulation of macroautophagy [GO:0016239]; spermatogenesis [GO:0007283]	xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; platelet-activating factor acetyltransferase activity [GO:0047179]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	acetylxylan esterase activity [GO:0046555]
d1vyja2_d2polb2__1	Metazoa		Chordata	Proteobacteria	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1vyja2_d3p83a2__1	Metazoa		Chordata	Euryarchaeota	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]		chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d1vyjc1_d1b8hb2__1	Metazoa		Chordata		centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]		chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1vyjc2_d1rwza2__1	Metazoa		Chordata	Euryarchaeota	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]		chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d1vyjc2_d5e0ta1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d1vyjk2_d2xurb2__1	Metazoa		Chordata	Proteobacteria	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1vyma2_d4n97b3__1	Metazoa		Chordata	Proteobacteria	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1vymb2_d5e0tc1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d1vymc2_d2io4b2__1	Metazoa		Chordata	Crenarchaeota	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	PCNA complex [GO:0043626]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d1vyra__d3w84a___1			Proteobacteria		FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d1vz0a1_d1r71d___1			Deinococcus-Thermus	Proteobacteria	DNA binding [GO:0003677]; chromosome segregation [GO:0007059]	protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein homodimerization activity [GO:0042803]; negative regulation of transcription, DNA-templated [GO:0045892]	chromosome segregation [GO:0007059]	negative regulation of transcription, DNA-templated [GO:0045892]		protein-containing complex [GO:0032991]	DNA binding [GO:0003677]	DNA binding [GO:0003677]; protein homodimerization activity [GO:0042803]
d1vz0c2_d3cyia1__1		Metazoa	Deinococcus-Thermus	Chordata	DNA binding [GO:0003677]; chromosome segregation [GO:0007059]	cytosol [GO:0005829]; ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]; cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	chromosome segregation [GO:0007059]	cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]	DNA binding [GO:0003677]	ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]
d1vz0d1_d1r71a___1			Deinococcus-Thermus	Proteobacteria	DNA binding [GO:0003677]; chromosome segregation [GO:0007059]	protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein homodimerization activity [GO:0042803]; negative regulation of transcription, DNA-templated [GO:0045892]	chromosome segregation [GO:0007059]	negative regulation of transcription, DNA-templated [GO:0045892]		protein-containing complex [GO:0032991]	DNA binding [GO:0003677]	DNA binding [GO:0003677]; protein homodimerization activity [GO:0042803]
d1vz2a1_d4re6b1__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type peptidase activity [GO:0008236]
d1vz2a2_d5alua2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d1vz3a1_d4re6a1__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type peptidase activity [GO:0008236]
d1vz3a2_d1cufa___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cutinase activity [GO:0050525]
d1vzca__d3ijza___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d1vzgb1_d4bffo___1			Proteobacteria	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d1vzha1_d2amua1__1			Proteobacteria	Thermotogae	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d1vzhb1_d4bffl___1			Proteobacteria	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d1vzib1_d4bfff___1			Proteobacteria	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d1vzta__d3dj4a1__1	Metazoa		Chordata	Actinobacteria	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]; adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]
d1vzub__d5nr9b___1	Metazoa	Metazoa	Chordata	Chordata	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d1w01a__d4jf8a___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	integral component of membrane [GO:0016021]; protein secretion by the type IV secretion system [GO:0030255]	steroid metabolic process [GO:0008202]	protein secretion by the type IV secretion system [GO:0030255]		integral component of membrane [GO:0016021]	steroid delta-isomerase activity [GO:0004769]	
d1w03a__d5pjfa___1	Fungi	Metazoa	Ascomycota	Chordata	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]; penicillin biosynthetic process [GO:0042318]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	penicillin biosynthetic process [GO:0042318]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]		blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d1w07b2_d1is2a1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]; peroxisome [GO:0005777]; plasmodesma [GO:0009506]; acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; jasmonic acid biosynthetic process [GO:0009695]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676]; response to cadmium ion [GO:0046686]; response to fungus [GO:0009620]; response to wounding [GO:0009611]	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; palmitoyl-CoA oxidase activity [GO:0016401]; protein homodimerization activity [GO:0042803]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693]; very long-chain fatty acid metabolic process [GO:0000038]	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; jasmonic acid biosynthetic process [GO:0009695]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676]; response to cadmium ion [GO:0046686]; response to fungus [GO:0009620]; response to wounding [GO:0009611]	fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693]; very long-chain fatty acid metabolic process [GO:0000038]	cytosol [GO:0005829]; peroxisome [GO:0005777]; plasmodesma [GO:0009506]	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; palmitoyl-CoA oxidase activity [GO:0016401]; protein homodimerization activity [GO:0042803]
d1w0ba__d1z8uc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; hemoglobin complex [GO:0005833]; hemoglobin binding [GO:0030492]; unfolded protein binding [GO:0051082]; erythrocyte differentiation [GO:0030218]; hemoglobin metabolic process [GO:0020027]; hemopoiesis [GO:0030097]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	erythrocyte differentiation [GO:0030218]; hemoglobin metabolic process [GO:0020027]; hemopoiesis [GO:0030097]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin binding [GO:0030492]; unfolded protein binding [GO:0051082]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1w0da1_d7icda___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1w0ia1_d4jrmd1__1	Viridiplantae		Streptophyta	Proteobacteria	mitochondrion [GO:0005739]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; thylakoid membrane organization [GO:0010027]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; thylakoid membrane organization [GO:0010027]	fatty acid biosynthetic process [GO:0006633]	mitochondrion [GO:0005739]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1w0ia2_d4jaqb1__1	Viridiplantae		Streptophyta	Actinobacteria	mitochondrion [GO:0005739]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; thylakoid membrane organization [GO:0010027]	polyketide synthase complex [GO:0034081]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; thylakoid membrane organization [GO:0010027]	chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	mitochondrion [GO:0005739]	polyketide synthase complex [GO:0034081]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1w0jb2_d3a5cb1__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1w0jb3_d2jlub1__1	Metazoa		Chordata		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	ATP synthesis coupled proton transport [GO:0015986]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1w0jc2_d3gqbc1__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1w0jd1_d2qe7f3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1w0jd1_d3oe7o3__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1w0je1_d2jj2a3__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1w0je2_d5hkkd1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1w0jf2_d3a5ce1__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1w0kc1_d1h8he1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1w0kd1_d3dsrb3__1	Metazoa		Chordata	Euryarchaeota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1w0ma__d4bi5i___1			Crenarchaeota		cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	triose-phosphate isomerase activity [GO:0004807]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]
d1w0md__d2vfga___1			Crenarchaeota	Apicomplexa	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]		triose-phosphate isomerase activity [GO:0004807]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]
d1w0md__d4jeqf___1			Crenarchaeota		cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1w0me__d2veia___1			Crenarchaeota		cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1w0mh__d5tima___1			Crenarchaeota		cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1w0na__d3cqob1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	metal ion binding [GO:0046872]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]		alpha-L-arabinofuranosidase activity [GO:0046556]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1w0wb2_d2w9lv___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1w11u__d1o3ea___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	digestion [GO:0007586]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1w13u__d4inka___1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular region [GO:0005576]; serine-type peptidase activity [GO:0008236]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type peptidase activity [GO:0008236]
d1w17a__d2c1ia1__1			Firmicutes	Firmicutes	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]; sporulation resulting in formation of a cellular spore [GO:0030435]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]; sporulation resulting in formation of a cellular spore [GO:0030435]	carbohydrate metabolic process [GO:0005975]; pathogenesis [GO:0009405]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]
d1w17b__d3cl8b___1			Firmicutes	Proteobacteria	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]; sporulation resulting in formation of a cellular spore [GO:0030435]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]; sporulation resulting in formation of a cellular spore [GO:0030435]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]
d1w1da1_d4rmab3__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]	3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]
d1w1ga1_d2g35a1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]
d1w1ha__d1m7ra1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]; identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]	3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]	identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1w1hc__d4zrkc3__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d1w1hd__d1oqna___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; growth cone [GO:0030426]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; integral component of membrane [GO:0016021]; main axon [GO:0044304]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; terminal bouton [GO:0043195]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; growth factor receptor binding [GO:0070851]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; peptidase activator activity [GO:0016504]; PTB domain binding [GO:0051425]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron differentiation [GO:0045665]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein binding [GO:0032092]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein phosphorylation [GO:0006468]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of translation [GO:0006417]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	activation of MAPK activity [GO:0000187]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron differentiation [GO:0045665]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein binding [GO:0032092]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein phosphorylation [GO:0006468]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of translation [GO:0006417]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; growth cone [GO:0030426]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; integral component of membrane [GO:0016021]; main axon [GO:0044304]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; terminal bouton [GO:0043195]	3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]	DNA binding [GO:0003677]; enzyme binding [GO:0019899]; growth factor receptor binding [GO:0070851]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; peptidase activator activity [GO:0016504]; PTB domain binding [GO:0051425]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; transition metal ion binding [GO:0046914]
d1w1ib2_d1yajc1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d1w1ic2_d4re6a2__1	Metazoa		Chordata	Crenarchaeota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	serine-type peptidase activity [GO:0008236]
d1w1jb1_d2bvfa2__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]		FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]
d1w1ka1_d5fxda2__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]		FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1w1lb1_d1ahua1__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	methanol metabolic process [GO:0015945]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1w1lb1_d5fxdb2__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]		FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1w1pb2_d4mava2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	carbohydrate metabolic process [GO:0005975]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]
d1w1ra2_d1ffvc2__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular space [GO:0005615]; cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytokinin metabolic process [GO:0009690]		extracellular space [GO:0005615]		cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1w1tb2_d1rd6a3__1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d1w1va2_d1nwsc2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; specific granule lumen [GO:0035580]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; extracellular matrix structural constituent [GO:0005201]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; neutrophil degranulation [GO:0043312]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	carbohydrate metabolic process [GO:0005975]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; neutrophil degranulation [GO:0043312]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; specific granule lumen [GO:0035580]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; extracellular matrix structural constituent [GO:0005201]
d1w1xa__d1usra___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]
d1w1xb__d1dima___1			Negarnaviricota	Proteobacteria	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]
d1w1xc__d4yw3a2__1			Negarnaviricota	Firmicutes	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1w1xd__d2b8hc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1w1yb2_d1nwtd2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; specific granule lumen [GO:0035580]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; extracellular matrix structural constituent [GO:0005201]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; neutrophil degranulation [GO:0043312]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	carbohydrate metabolic process [GO:0005975]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; neutrophil degranulation [GO:0043312]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; specific granule lumen [GO:0035580]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; extracellular matrix structural constituent [GO:0005201]
d1w1zb__d3si9b1__1			Chlorobi	Proteobacteria	metal ion binding [GO:0046872]; porphobilinogen synthase activity [GO:0004655]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	protoporphyrinogen IX biosynthetic process [GO:0006782]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; porphobilinogen synthase activity [GO:0004655]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1w20a__d1v3eb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d1w20b__d2fhra2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1w20b__d3beqa___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1w20d__d4i00a1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1w25a2_d1zh4b___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of transcription, DNA-templated [GO:0006355]	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]	regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1w25b2_d5tqja___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]		diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]	
d1w2ta1_d3biwh1__1		Metazoa	Thermotogae	Chordata	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	cell junction [GO:0030054]; cell projection [GO:0042995]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; vesicle [GO:0031982]; acetylcholine receptor binding [GO:0033130]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; adult behavior [GO:0030534]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; learning [GO:0007612]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuromuscular process controlling balance [GO:0050885]; neurotransmitter secretion [GO:0007269]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein heterotetramerization [GO:0051290]; regulation of grooming behavior [GO:2000821]; synapse assembly [GO:0007416]; vesicle docking involved in exocytosis [GO:0006904]	carbohydrate metabolic process [GO:0005975]	adult behavior [GO:0030534]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; learning [GO:0007612]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuromuscular process controlling balance [GO:0050885]; neurotransmitter secretion [GO:0007269]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein heterotetramerization [GO:0051290]; regulation of grooming behavior [GO:2000821]; synapse assembly [GO:0007416]; vesicle docking involved in exocytosis [GO:0006904]		cell junction [GO:0030054]; cell projection [GO:0042995]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; vesicle [GO:0031982]	beta-fructofuranosidase activity [GO:0004564]	acetylcholine receptor binding [GO:0033130]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]
d1w2ta1_d3nv2a___1		Metazoa	Thermotogae	Chordata	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	carbohydrate metabolic process [GO:0005975]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	beta-fructofuranosidase activity [GO:0004564]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]
d1w2ta2_d4udge___1			Thermotogae		beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				beta-fructofuranosidase activity [GO:0004564]	
d1w2tc2_d1uypc2__1			Thermotogae	Thermotogae	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			beta-fructofuranosidase activity [GO:0004564]	beta-fructofuranosidase activity [GO:0004564]
d1w2td1_d1cr7d___1		Viridiplantae	Thermotogae	Streptophyta	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]				beta-fructofuranosidase activity [GO:0004564]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1w2td2_d4udjb___1			Thermotogae		beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				beta-fructofuranosidase activity [GO:0004564]	
d1w2te1_d1avba___1		Viridiplantae	Thermotogae	Streptophyta	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; nutrient reservoir activity [GO:0045735]; toxin activity [GO:0090729]; defense response [GO:0006952]	carbohydrate metabolic process [GO:0005975]	defense response [GO:0006952]			beta-fructofuranosidase activity [GO:0004564]	carbohydrate binding [GO:0030246]; nutrient reservoir activity [GO:0045735]; toxin activity [GO:0090729]
d1w2te2_d2exhd2__1			Thermotogae	Firmicutes	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			beta-fructofuranosidase activity [GO:0004564]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1w2tf1_d3n3ha___1		Viridiplantae	Thermotogae	Streptophyta	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]	carbohydrate metabolic process [GO:0005975]				beta-fructofuranosidase activity [GO:0004564]	carbohydrate binding [GO:0030246]
d1w2va__d2bvta2__1			Proteobacteria	Actinobacteria	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]			cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]
d1w2va__d2qv4a2__1		Metazoa	Proteobacteria	Chordata	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	xylan catabolic process [GO:0045493]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1w2za3_d2zl8b2__1	Viridiplantae		Streptophyta	Actinobacteria	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; oxidation-reduction process [GO:0055114]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; oxidation-reduction process [GO:0055114]	amine metabolic process [GO:0009308]			aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d1w2zd2_d1spub3__1	Viridiplantae		Streptophyta	Proteobacteria	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; oxidation-reduction process [GO:0055114]	amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]		periplasmic space [GO:0042597]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d1w31a__d3uqna___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1w32a__d5h4ra___1			Proteobacteria	Firmicutes	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1w32b__d1hn1a5__1			Proteobacteria	Proteobacteria	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1w35a2_d4yafb3__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	phycobilisome [GO:0030089]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1w37a__d1j4ea___1		Metazoa	Crenarchaeota	Chordata	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]		I band [GO:0031674]; M band [GO:0031430]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]	fructose-bisphosphate aldolase activity [GO:0004332]
d1w37b__d4s2bb___1			Crenarchaeota	Proteobacteria	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; membrane [GO:0016020]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		cytosol [GO:0005829]; membrane [GO:0016020]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]
d1w37c__d2nx3j___1			Crenarchaeota	Aquificae	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	carbohydrate metabolic process [GO:0005975]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]		cytoplasm [GO:0005737]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]
d1w39c__d1asj3___1					T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1w3hb__d4pmuc___1			Proteobacteria	Proteobacteria	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d1w3ib__d2v8zb___1			Crenarchaeota	Proteobacteria	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; 2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]; aldonic acid catabolic process [GO:0046176]	carbohydrate metabolic process [GO:0005975]	aldonic acid catabolic process [GO:0046176]		cytoplasm [GO:0005737]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]
d1w3ib__d4tu1a1__1			Crenarchaeota	Apicomplexa	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	apical cytoplasm [GO:0090651]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; actin filament binding [GO:0051015]; fructose-bisphosphate aldolase activity [GO:0004332]; adhesion of symbiont to host cell [GO:0044650]; entry into host cell [GO:0030260]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; glycolytic process [GO:0006096]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of cell population proliferation [GO:0008284]; symbiotic process [GO:0044403]	carbohydrate metabolic process [GO:0005975]	adhesion of symbiont to host cell [GO:0044650]; entry into host cell [GO:0030260]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; glycolytic process [GO:0006096]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of cell population proliferation [GO:0008284]; symbiotic process [GO:0044403]		apical cytoplasm [GO:0090651]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]	actin filament binding [GO:0051015]; fructose-bisphosphate aldolase activity [GO:0004332]
d1w3ja__d2xvna___1		Fungi	Thermotogae	Ascomycota	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	anchored component of membrane [GO:0031225]; cell wall [GO:0005618]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		anchored component of membrane [GO:0031225]; cell wall [GO:0005618]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d1w3ka__d3f5ia___1			Firmicutes		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	
d1w3la__d2j25b2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	cellulose catabolic process [GO:0030245]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1w3nc__d3lchb___1			Crenarchaeota	Proteobacteria	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]		cytosol [GO:0005829]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d1w3nd__d1eunb___1			Crenarchaeota	Proteobacteria	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]	metabolic process [GO:0008152]		cytosol [GO:0005829]; membrane [GO:0016020]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]	(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]
d1w3oa1_d5jabc___1			Deinococcus-Thermus	Actinobacteria	cofactor binding [GO:0048037]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; coenzyme F420 binding [GO:0070967]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; protein homodimerization activity [GO:0042803]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]	cofactor binding [GO:0048037]	coenzyme F420 binding [GO:0070967]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; protein homodimerization activity [GO:0042803]
d1w3ra1_d3a6qa___1			Deinococcus-Thermus	Proteobacteria	cofactor binding [GO:0048037]	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	cofactor binding [GO:0048037]	cofactor binding [GO:0048037]
d1w3ra1_d5chof___1			Deinococcus-Thermus		cofactor binding [GO:0048037]	FMN binding [GO:0010181]					cofactor binding [GO:0048037]	FMN binding [GO:0010181]
d1w3ta__d1rqea2__1			Crenarchaeota	Actinobacteria	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]	carbohydrate metabolic process [GO:0005975]				2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]	metal ion binding [GO:0046872]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]
d1w3tc__d4icna___1			Crenarchaeota	Proteobacteria	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1w3ya3_d1rwca3__1			Firmicutes	Actinobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]
d1w3ya3_d3vd7b5__1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	cell wall [GO:0005618]; extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1w4pb__d1rbf.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1w4qb__d5m9tb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]
d1w4vb1_d2riib___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein disulfide oxidoreductase activity [GO:0015035]; protein-containing complex binding [GO:0044877]; cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cytosol [GO:0005829]; ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]; cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]	cytosol [GO:0005829]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein-containing complex binding [GO:0044877]; protein disulfide oxidoreductase activity [GO:0015035]	ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]
d1w4wa__d5sxxa2__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1w4ya__d2pccc___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; vacuole [GO:0005773]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d1w55a2_d1iv4b___1			Proteobacteria	Deinococcus-Thermus	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [GO:0050518]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [GO:0050518]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d1w56a__d1w1zb___1			Proteobacteria	Chlorobi	cytosol [GO:0005829]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]; heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	metal ion binding [GO:0046872]; porphobilinogen synthase activity [GO:0004655]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]		porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; porphobilinogen synthase activity [GO:0004655]
d1w59a1_d4u39a1__1			Euryarchaeota	Firmicutes	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cell division site [GO:0032153]; cell septum [GO:0030428]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	cell division site [GO:0032153]; cell septum [GO:0030428]; cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1w5eb1_d5ezyc1__1		Metazoa	Euryarchaeota	Chordata	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1w5eb2_d5iyzb2__1		Metazoa	Euryarchaeota	Chordata	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1w5ed1_d4f6ra1__1		Metazoa	Euryarchaeota	Chordata	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; structural constituent of cytoskeleton [GO:0005200]; microtubule-based process [GO:0007017]	cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	microtubule-based process [GO:0007017]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; microtubule [GO:0005874]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; structural constituent of cytoskeleton [GO:0005200]
d1w5ee2_d4lnub2__1		Metazoa	Euryarchaeota	Chordata	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; structural constituent of cytoskeleton [GO:0005200]; microtubule-based process [GO:0007017]	cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	microtubule-based process [GO:0007017]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; microtubule [GO:0005874]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; structural constituent of cytoskeleton [GO:0005200]
d1w5oa__d5f4xd___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]; heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]	I band [GO:0031674]; M band [GO:0031430]	porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]	fructose-bisphosphate aldolase activity [GO:0004332]
d1w5rb__d1gx3a___1			Actinobacteria	Actinobacteria	arylamine N-acetyltransferase activity [GO:0004060]	arylamine N-acetyltransferase activity [GO:0004060]					arylamine N-acetyltransferase activity [GO:0004060]	arylamine N-acetyltransferase activity [GO:0004060]
d1w5sb2_d3hu1f3__1		Metazoa	Crenarchaeota	Chordata	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA replication [GO:0006260]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	DNA replication [GO:0006260]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATP binding [GO:0005524]; DNA binding [GO:0003677]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1w5tc2_d1nbma3__1		Metazoa	Crenarchaeota	Chordata	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA replication [GO:0006260]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	DNA replication [GO:0006260]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; DNA binding [GO:0003677]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1w5ya__d3pepa___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1w5yb__d2b7zb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1w5yb__d5dr7a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1w60a1_d4mjqb3__1	Metazoa		Chordata	Proteobacteria	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1w60a2_d5f7ie1__1	Metazoa		Chordata		centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]		base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]		centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]		chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	
d1w60b1_d4n96a2__1	Metazoa		Chordata	Proteobacteria	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1w61a__d2gkea1__1				Proteobacteria	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; membrane [GO:0016020]; proline racemase activity [GO:0018112]; multicellular organism development [GO:0007275]	cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	multicellular organism development [GO:0007275]	lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; membrane [GO:0016020]	cytosol [GO:0005829]	proline racemase activity [GO:0018112]	diaminopimelate epimerase activity [GO:0008837]
d1w66a1_d2akwb6__1			Actinobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; lipoyl(octanoyl) transferase activity [GO:0033819]; octanoyl transferase activity (acting on glycine-cleavage complex H protein) [GO:0102555]; lipoate biosynthetic process [GO:0009107]; protein lipoylation [GO:0009249]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	lipoate biosynthetic process [GO:0009107]; protein lipoylation [GO:0009249]	phenylalanyl-tRNA aminoacylation [GO:0006432]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	lipoyl(octanoyl) transferase activity [GO:0033819]; octanoyl transferase activity (acting on glycine-cleavage complex H protein) [GO:0102555]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]
d1w69a__d3rnba___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]	cellular aromatic compound metabolic process [GO:0006725]	cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]		ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d1w6fa__d1e2te___1			Actinobacteria	Proteobacteria	arylamine N-acetyltransferase activity [GO:0004060]	cytoplasm [GO:0005737]; arylamine N-acetyltransferase activity [GO:0004060]; N-hydroxyarylamine O-acetyltransferase activity [GO:0046990]				cytoplasm [GO:0005737]	arylamine N-acetyltransferase activity [GO:0004060]	arylamine N-acetyltransferase activity [GO:0004060]; N-hydroxyarylamine O-acetyltransferase activity [GO:0046990]
d1w6fc__d1kv3d4__1		Metazoa	Actinobacteria	Chordata	arylamine N-acetyltransferase activity [GO:0004060]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]		apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]		cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	arylamine N-acetyltransferase activity [GO:0004060]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d1w6ka2_d3d5rb2__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; membrane [GO:0016020]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; cholesterol biosynthetic process [GO:0006695]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of protein stability [GO:0031647]; steroid biosynthetic process [GO:0006694]; triterpenoid biosynthetic process [GO:0016104]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	cholesterol biosynthetic process [GO:0006695]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of protein stability [GO:0031647]; steroid biosynthetic process [GO:0006694]; triterpenoid biosynthetic process [GO:0016104]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; membrane [GO:0016020]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d1w6la2_d5a7ea2__1		Fungi	Firmicutes	Basidiomycota	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1w6la3_d3ef4a___1			Firmicutes	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1w6mb__d2zhkb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]
d1w6mb__d4lbma___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d1w6ob__d1qdcd___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1w6tb1_d2psnd2__1		Metazoa	Firmicutes	Chordata	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d1w6wa2_d4k9ja___1			Firmicutes	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	sporulation resulting in formation of a cellular spore [GO:0030435]	oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1w6wa3_d3t6zb2__1		Fungi	Firmicutes	Basidiomycota	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1w6za__d114la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1w72d1_d1cfvh1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]
d1w72d2_d4l4vc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1w72e1_d1frtc2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1w72i1_d4rbpk1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1w72l1_d3qctl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1w72l2_d3ch1g2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1w72m1_d1xaua___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; negative regulation of alpha-beta T cell proliferation [GO:0046642]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of T cell proliferation [GO:0042130]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; negative regulation of alpha-beta T cell proliferation [GO:0046642]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of T cell proliferation [GO:0042130]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	signaling receptor activity [GO:0038023]
d1w72m2_d1dqlh___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1w72m2_d6blqa2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1w74a__d2b71a1__1			Actinobacteria	Apicomplexa	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]; response to iron ion [GO:0010039]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	protein folding [GO:0006457]; response to iron ion [GO:0010039]	protein folding [GO:0006457]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1w7pa1_d1w7pd1__1	Fungi	Fungi	Ascomycota	Ascomycota	cell [GO:0005623]; ESCRT II complex [GO:0000814]; late endosome membrane [GO:0031902]; metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266]; ubiquitin binding [GO:0043130]; ATP export [GO:1904669]; carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [GO:0000433]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	cell [GO:0005623]; ESCRT II complex [GO:0000814]; late endosome membrane [GO:0031902]; metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266]; ubiquitin binding [GO:0043130]; ATP export [GO:1904669]; carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [GO:0000433]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	ATP export [GO:1904669]; carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [GO:0000433]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	ATP export [GO:1904669]; carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [GO:0000433]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	cell [GO:0005623]; ESCRT II complex [GO:0000814]; late endosome membrane [GO:0031902]	cell [GO:0005623]; ESCRT II complex [GO:0000814]; late endosome membrane [GO:0031902]	metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266]; ubiquitin binding [GO:0043130]	metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266]; ubiquitin binding [GO:0043130]
d1w7wc__d1vyag___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		nucleus [GO:0005634]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]
d1w85b2_d2c3ua3__1			Firmicutes	Proteobacteria	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	glycolytic process [GO:0006096]	electron transport chain [GO:0022900]		cytoplasm [GO:0005737]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d1w85d1_d2bp7b1__1			Firmicutes	Proteobacteria	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]	glycolytic process [GO:0006096]				pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]
d1w85d2_d3exed2__1		Metazoa	Firmicutes	Chordata	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1w85f1_d1qgdb1__1			Firmicutes	Proteobacteria	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	glycolytic process [GO:0006096]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d1w85f2_d2j9fb2__1		Metazoa	Firmicutes	Chordata	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]		mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]
d1w87b2_d1ja1a3__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	phycobilisome [GO:0030089]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d1w88b1_d3e9ya1__1		Viridiplantae	Firmicutes	Streptophyta	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	glycolytic process [GO:0006096]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1w88b2_d1umdb2__1			Firmicutes	Deinococcus-Thermus	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	glycolytic process [GO:0006096]				pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]
d1w88d2_d1tkca3__1		Fungi	Firmicutes	Ascomycota	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]	pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1w88f2_d2c3ub3__1			Firmicutes	Proteobacteria	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	glycolytic process [GO:0006096]	electron transport chain [GO:0022900]		cytoplasm [GO:0005737]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d1w88h2_d1olxb2__1		Metazoa	Firmicutes	Chordata	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]		mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]
d1w88h2_d2r5na3__1			Firmicutes	Proteobacteria	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	glycolytic process [GO:0006096]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d1w89a1_d2h0ga1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein disulfide oxidoreductase activity [GO:0015035]; protein-containing complex binding [GO:0044877]; cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]		cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]	periplasmic space [GO:0042597]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein-containing complex binding [GO:0044877]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d1w89b1_d5ecpb1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein disulfide oxidoreductase activity [GO:0015035]; protein-containing complex binding [GO:0044877]; cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein-containing complex binding [GO:0044877]; protein disulfide oxidoreductase activity [GO:0015035]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d1w89c__d2z9sb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein disulfide oxidoreductase activity [GO:0015035]; protein-containing complex binding [GO:0044877]; cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]; heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein-containing complex binding [GO:0044877]; protein disulfide oxidoreductase activity [GO:0015035]	heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d1w89d1_d4k7ob___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein disulfide oxidoreductase activity [GO:0015035]; protein-containing complex binding [GO:0044877]; cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein-containing complex binding [GO:0044877]; protein disulfide oxidoreductase activity [GO:0015035]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]
d1w8ea2_d5i6ka2__1			Firmicutes	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	sporulation resulting in formation of a cellular spore [GO:0030435]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1w8ea3_d3in0d___1			Firmicutes	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	sporulation resulting in formation of a cellular spore [GO:0030435]	oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1w8fa__d2vnvb___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1w8fb__d5mb1b___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1w8fd__d5mb1c___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1w8ha__d4ut5c___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1w8la__d2nnza___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]		entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	
d1w8na2_d3puhb2__1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	metabolic process [GO:0008152]	cocaine catabolic process [GO:0050784]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]
d1w8na3_d1a4qb___1			Actinobacteria	Negarnaviricota	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	extracellular region [GO:0005576]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1w8oa1_d1urzb1__1			Actinobacteria		extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	metabolic process [GO:0008152]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1w8oa2_d1jz1j3__1			Actinobacteria		extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]		metabolic process [GO:0008152]		extracellular region [GO:0005576]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	
d1w8rb__d3fkkb___1				Proteobacteria		2-dehydro-3-deoxy-L-arabinonate dehydratase activity [GO:0047449]; protein homodimerization activity [GO:0042803]; L-arabinose catabolic process to 2-oxoglutarate [GO:0019570]		L-arabinose catabolic process to 2-oxoglutarate [GO:0019570]				2-dehydro-3-deoxy-L-arabinonate dehydratase activity [GO:0047449]; protein homodimerization activity [GO:0042803]
d1w8rc__d1qo5r___1		Metazoa		Chordata		centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose binding [GO:0070061]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]; canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]		canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]		centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]		ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose binding [GO:0070061]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]
d1w8rd__d1epxd___1						fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]				fructose-bisphosphate aldolase activity [GO:0004332]
d1w8rd__d3pg9h___1				Thermotogae		3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]				3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]
d1w8rf__d3irda___1				Firmicutes		cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]		4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1w8sb__d3pg9d___1			Crenarchaeota	Thermotogae	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	glycolytic process [GO:0006096]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]		fructose-bisphosphate aldolase activity [GO:0004332]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]
d1w8sd__d4jn6a1__1			Crenarchaeota	Actinobacteria	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]; aromatic compound catabolic process [GO:0019439]	glycolytic process [GO:0006096]	aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]		fructose-bisphosphate aldolase activity [GO:0004332]	acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; NAD binding [GO:0051287]
d1w8sh__d2wo5a1__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	fructose-bisphosphate aldolase activity [GO:0004332]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d1w8ua__d1jz1k3__1	Fungi		Chytridiomycota									
d1w8wa__d4aryd3__1	Fungi		Chytridiomycota	Firmicutes		signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]				signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d1w8za__d2bzdc3__1	Fungi		Chytridiomycota	Actinobacteria		extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]		metabolic process [GO:0008152]		extracellular region [GO:0005576]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1w8zb__d1ryya1__1	Fungi		Chytridiomycota	Proteobacteria		alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]						alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d1w90a1_d1w9fb___1	Fungi	Fungi	Chytridiomycota	Chytridiomycota								
d1w90b__d1w8zb___1	Fungi	Fungi	Chytridiomycota	Chytridiomycota								
d1w90b__d2vxjv___1	Fungi		Chytridiomycota	Proteobacteria		cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]		carbohydrate binding [GO:0030246]
d1w91a2_d3viga___1		Metazoa	Firmicutes	Arthropoda	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			xylan 1,4-beta-xylosidase activity [GO:0009044]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d1w91b2_d3t2pd3__1			Firmicutes	Proteobacteria	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	xylan 1,4-beta-xylosidase activity [GO:0009044]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1w91d2_d4pmda1__1			Firmicutes	Firmicutes	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			xylan 1,4-beta-xylosidase activity [GO:0009044]	endo-1,4-beta-xylanase activity [GO:0031176]
d1w91e2_d1f4ac5__1			Firmicutes	Proteobacteria	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	xylan 1,4-beta-xylosidase activity [GO:0009044]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1w91e2_d4ee9a___1			Firmicutes		xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	cellulase activity [GO:0008810]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			xylan 1,4-beta-xylosidase activity [GO:0009044]	cellulase activity [GO:0008810]
d1w91f2_d1j0ja3__1			Firmicutes	Firmicutes	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			xylan 1,4-beta-xylosidase activity [GO:0009044]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1w91h2_d2j62a2__1			Firmicutes	Firmicutes	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]			xylan 1,4-beta-xylosidase activity [GO:0009044]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d1w96b2_d5njhf1__1	Fungi	Metazoa	Ascomycota	Chordata	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d1w98b2_d1p5ed1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1w99a3_d1ciya1__1			Firmicutes	Firmicutes	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]			signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d1w99a3_d3t0ad1__1			Firmicutes	Proteobacteria	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	sporulation resulting in formation of a cellular spore [GO:0030435]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1w9ea1_d2uzcc___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]; actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	actin cytoskeleton [GO:0015629]; cell projection [GO:0042995]; cell-cell adherens junction [GO:0005913]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; membrane [GO:0016020]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; actinin binding [GO:0042805]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase C binding [GO:0005080]; protein N-terminus binding [GO:0047485]; actin cytoskeleton organization [GO:0030036]; cell growth involved in cardiac muscle cell development [GO:0061049]; heart development [GO:0007507]; muscle structure development [GO:0061061]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of synapse assembly [GO:0051963]	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	actin cytoskeleton organization [GO:0030036]; cell growth involved in cardiac muscle cell development [GO:0061049]; heart development [GO:0007507]; muscle structure development [GO:0061061]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of synapse assembly [GO:0051963]	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]	actin cytoskeleton [GO:0015629]; cell-cell adherens junction [GO:0005913]; cell projection [GO:0042995]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; membrane [GO:0016020]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; stress fiber [GO:0001725]; Z disc [GO:0030018]	cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]	actin binding [GO:0003779]; actinin binding [GO:0042805]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase C binding [GO:0005080]; protein N-terminus binding [GO:0047485]
d1w9eb2_d2zlej1__1	Metazoa		Chordata	Proteobacteria	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]; actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1w9oa1_d1n6ee1__1	Metazoa		Chordata	Euryarchaeota	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]; actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	proteolysis [GO:0006508]	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]	cytoplasm [GO:0005737]	cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]	serine-type peptidase activity [GO:0008236]
d1w9ob2_d2vrfb1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]; actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	cytoplasm [GO:0005737]; dystrophin-associated glycoprotein complex [GO:0016010]; focal adhesion [GO:0005925]; membrane [GO:0016020]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]		adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]	cytoplasm [GO:0005737]; dystrophin-associated glycoprotein complex [GO:0016010]; focal adhesion [GO:0005925]; membrane [GO:0016020]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658]	cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]	actin binding [GO:0003779]; calmodulin binding [GO:0005516]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1w9qa2_d2zlem1__1	Metazoa		Chordata	Proteobacteria	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]; actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1w9qb1_d2vsvb1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]; actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; signal transduction [GO:0007165]	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; neutrophil degranulation [GO:0043312]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting to membrane [GO:0006612]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930]	signal transduction [GO:0007165]	adherens junction [GO:0005912]; azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; focal adhesion [GO:0005925]; interleukin-5 receptor complex [GO:0005895]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]	cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]	cytoskeletal adaptor activity [GO:0008093]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; interleukin-5 receptor binding [GO:0005137]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; syndecan binding [GO:0045545]	
d1w9sa__d1uyyb___1			Firmicutes	Proteobacteria	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group [GO:0052861]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group [GO:0052861]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1w9sb__d1o8sa___1			Firmicutes	Firmicutes	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group [GO:0052861]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]		cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group [GO:0052861]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]
d1w9ta__d4lk6j___1			Firmicutes	Proteobacteria	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group [GO:0052861]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group [GO:0052861]	carbohydrate binding [GO:0030246]
d1w9xa1_d3h55a2__1		Metazoa	Firmicutes	Chordata	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d1wa0x1_d1e30a___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	nitrogen compound metabolic process [GO:0006807]			periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1wa0x1_d1w6la3__1			Proteobacteria	Firmicutes	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	nitrogen compound metabolic process [GO:0006807]	sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1wa1x2_d4g7rb2__1			Proteobacteria	Deinococcus-Thermus	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	nitrogen compound metabolic process [GO:0006807]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d1wa3a__d1ok4e___1			Thermotogae	Crenarchaeota	lyase activity [GO:0016829]	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	lyase activity [GO:0016829]	fructose-bisphosphate aldolase activity [GO:0004332]
d1wa3a__d3flub___1			Thermotogae	Proteobacteria	lyase activity [GO:0016829]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]	lyase activity [GO:0016829]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1wa3b__d1vpxc1__1			Thermotogae	Thermotogae	lyase activity [GO:0016829]	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]		carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]	lyase activity [GO:0016829]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d1wa8b1_d4j41d___1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; host cell surface binding [GO:0046812]; protein homodimerization activity [GO:0042803]; modulation by symbiont of host signal transduction pathway [GO:0052027]; negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein secretion by the type VII secretion system [GO:0044315]		modulation by symbiont of host signal transduction pathway [GO:0052027]; negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein secretion by the type VII secretion system [GO:0044315]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		host cell surface binding [GO:0046812]; protein homodimerization activity [GO:0042803]	
d1waaa__d4mngf2__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1waac__d1t0ma1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1waac__d1z7zi5__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]
d1waae__d3ivkb1__1	Metazoa		Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	
d1waae__d5xjfc1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	adaptive immune response [GO:0002250]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	
d1wada__d3ouqa1__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	metal ion binding [GO:0046872]	anaerobic respiration [GO:0009061]				electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1wala__d3vl7a1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	cytosol [GO:0005829]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	leucine biosynthetic process [GO:0009098]	leucine biosynthetic process [GO:0009098]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1wao32_d1t70b___1	Metazoa		Chordata	Deinococcus-Thermus	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]; phosphoenolpyruvate phosphatase activity [GO:0050189]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]; phosphoenolpyruvate phosphatase activity [GO:0050189]
d1wao42_d4dt2d2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	extracellular region [GO:0005576]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]
d1wapa__d1gtna___1			Firmicutes	Firmicutes	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d1wapd__d1c9sa___1			Firmicutes	Firmicutes	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d1wapf__d1utfs___1			Firmicutes		RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]		DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]				RNA binding [GO:0003723]	
d1wapl__d1c9sq___1			Firmicutes	Firmicutes	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d1wapt__d1c9sp___1			Firmicutes	Firmicutes	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d1wara1_d2bcda___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; riboflavin metabolic process [GO:0006771]	cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; protein-containing complex [GO:0032991]; PTW/PP1 phosphatase complex [GO:0072357]; lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]	bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; riboflavin metabolic process [GO:0006771]	cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]	cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]	lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]
d1wata__d4z9hb___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; transmembrane signaling receptor activity [GO:0004888]; chemotaxis [GO:0006935]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; positive regulation of post-translational protein modification [GO:1901875]; protein homooligomerization [GO:0051260]; regulation of chemotaxis [GO:0050920]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; positive regulation of post-translational protein modification [GO:1901875]; protein homooligomerization [GO:0051260]; regulation of chemotaxis [GO:0050920]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]	transmembrane signaling receptor activity [GO:0004888]	protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]
d1watb__d1vltb___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; transmembrane signaling receptor activity [GO:0004888]; chemotaxis [GO:0006935]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; transmembrane signaling receptor activity [GO:0004888]; chemotaxis [GO:0006935]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]	integral component of plasma membrane [GO:0005887]	transmembrane signaling receptor activity [GO:0004888]	transmembrane signaling receptor activity [GO:0004888]
d1watb__d3atpa___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; transmembrane signaling receptor activity [GO:0004888]; chemotaxis [GO:0006935]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]; protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cell motility [GO:0048870]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; protein homooligomerization [GO:0051260]; receptor clustering [GO:0043113]; regulation of bacterial-type flagellum-dependent cell motility [GO:1902021]; regulation of chemotaxis [GO:0050920]; regulation of protein histidine kinase activity [GO:0032110]; response to amino acid [GO:0043200]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	cell motility [GO:0048870]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; protein homooligomerization [GO:0051260]; receptor clustering [GO:0043113]; regulation of bacterial-type flagellum-dependent cell motility [GO:1902021]; regulation of chemotaxis [GO:0050920]; regulation of protein histidine kinase activity [GO:0032110]; response to amino acid [GO:0043200]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]	transmembrane signaling receptor activity [GO:0004888]	protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]
d1waxa__d4y2eb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; activation of MAPK activity [GO:0000187]; MAPK cascade [GO:0000165]; negative regulation of MAP kinase activity [GO:0043407]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	activation of MAPK activity [GO:0000187]; MAPK cascade [GO:0000165]; negative regulation of MAP kinase activity [GO:0043407]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1wb0a2_d1zb5a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; endochitinase activity [GO:0008843]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; polysaccharide catabolic process [GO:0000272]; polysaccharide digestion [GO:0044245]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	chitin catabolic process [GO:0006032]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; polysaccharide catabolic process [GO:0000272]; polysaccharide digestion [GO:0044245]; response to bacterium [GO:0009617]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]; endochitinase activity [GO:0008843]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]
d1wb5b2_d1va5b___1			Firmicutes	Actinobacteria	cellulosome [GO:0043263]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cell wall [GO:0005618]; extracellular region [GO:0005576]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	xylan catabolic process [GO:0045493]	glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	cellulosome [GO:0043263]	cell wall [GO:0005618]; extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]
d1wb6a2_d1tgla___1		Fungi	Firmicutes	Mucoromycota	cellulosome [GO:0043263]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	xylan catabolic process [GO:0045493]	lipid catabolic process [GO:0016042]	cellulosome [GO:0043263]		endo-1,4-beta-xylanase activity [GO:0031176]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d1wb7a2_d2rcva2__1			Crenarchaeota	Firmicutes	cytoplasm [GO:0005737]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1wb7b1_d3ak2c1__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]		manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1wb8a1_d3rn4a1__1		Fungi	Crenarchaeota	Ascomycota	cytoplasm [GO:0005737]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; age-dependent response to oxidative stress involved in chronological cell aging [GO:0001324]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; reactive oxygen species metabolic process [GO:0072593]; replicative cell aging [GO:0001302]		age-dependent response to oxidative stress involved in chronological cell aging [GO:0001324]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; reactive oxygen species metabolic process [GO:0072593]; replicative cell aging [GO:0001302]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1wb8b1_d2w7wb1__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]		manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1wbfa__d1eg1c___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d1wbha1_d3lcxc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d1wbhb__d3daqa___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	metabolic process [GO:0008152]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1wbhc__d1j4ec___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	metabolic process [GO:0008152]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]; membrane [GO:0016020]	I band [GO:0031674]; M band [GO:0031430]	(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]	fructose-bisphosphate aldolase activity [GO:0004332]
d1wbhc__d1w1za___1			Proteobacteria	Chlorobi	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	metal ion binding [GO:0046872]; porphobilinogen synthase activity [GO:0004655]; protoporphyrinogen IX biosynthetic process [GO:0006782]	metabolic process [GO:0008152]	protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]; membrane [GO:0016020]		(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]	metal ion binding [GO:0046872]; porphobilinogen synthase activity [GO:0004655]
d1wbic__d2fhlb1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]; biotin transport [GO:0015878]	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin transport [GO:0015878]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1wbig__d1strb___1	Metazoa		Chordata	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]; biotin transport [GO:0015878]	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin transport [GO:0015878]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1wbig__d4z2pa___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]; biotin transport [GO:0015878]	extracellular region [GO:0005576]; biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]	biotin transport [GO:0015878]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]
d1wbja__d3n3ma1__1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1wblb__d2zhmb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]
d1wblc__d1lgc.1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d1wbld__d1wd4a1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; arabinose metabolic process [GO:0019566]; L-arabinose metabolic process [GO:0046373]; xylan catabolic process [GO:0045493]		arabinan catabolic process [GO:0031222]; arabinose metabolic process [GO:0019566]; L-arabinose metabolic process [GO:0046373]; xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]	alpha-L-arabinofuranosidase activity [GO:0046556]
d1wbmb__d3l5fb___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d1wbxa1_d1op5h2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1wbxb__d2fx8h2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d1wbya1_d4jfzl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1wbya1_d4oz4l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1wbya2_d1ieac2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1wbza1_d1jpgb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1wbza2_d2bsud3__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d1wbza2_d3m1bg1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1wbzb__d3t77b1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	metal ion binding [GO:0046872]
d1wbzc1_d3cmol2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1wc0a1_d1ybud___1			Cyanobacteria	Actinobacteria	adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; cyclic nucleotide biosynthetic process [GO:0009190]; protein-chromophore linkage [GO:0018298]	adenylate cyclase activity [GO:0004016]; guanylate cyclase activity [GO:0004383]; manganese ion binding [GO:0030145]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; cAMP biosynthetic process [GO:0006171]; cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]	cyclic nucleotide biosynthetic process [GO:0009190]; protein-chromophore linkage [GO:0018298]	cAMP biosynthetic process [GO:0006171]; cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]			adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]	adenylate cyclase activity [GO:0004016]; guanylate cyclase activity [GO:0004383]; manganese ion binding [GO:0030145]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]
d1wc1b__d3c15a___1		Metazoa	Cyanobacteria	Chordata	adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; cyclic nucleotide biosynthetic process [GO:0009190]; protein-chromophore linkage [GO:0018298]	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	cyclic nucleotide biosynthetic process [GO:0009190]; protein-chromophore linkage [GO:0018298]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]		cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]	adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d1wc5c1_d3uvjd___1		Metazoa	Cyanobacteria	Chordata	adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; cyclic nucleotide biosynthetic process [GO:0009190]; protein-chromophore linkage [GO:0018298]	guanylate cyclase complex, soluble [GO:0008074]; presynaptic active zone [GO:0048786]; GTP binding [GO:0005525]; guanylate cyclase activity [GO:0004383]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; blood circulation [GO:0008015]; cellular response to nitric oxide [GO:0071732]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; nitric oxide mediated signal transduction [GO:0007263]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; trans-synaptic signaling by nitric oxide, modulating synaptic transmission [GO:0099555]	cyclic nucleotide biosynthetic process [GO:0009190]; protein-chromophore linkage [GO:0018298]	blood circulation [GO:0008015]; cellular response to nitric oxide [GO:0071732]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; nitric oxide mediated signal transduction [GO:0007263]; trans-synaptic signaling by nitric oxide, modulating synaptic transmission [GO:0099555]		guanylate cyclase complex, soluble [GO:0008074]; presynaptic active zone [GO:0048786]	adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]	GTP binding [GO:0005525]; guanylate cyclase activity [GO:0004383]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]
d1wc7a1_d1lo0y2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1wc7b1_d1bafh1__1												
d1wc8a__d3kxca___1	Metazoa	Metazoa	Chordata	Chordata	cis-Golgi network membrane [GO:0033106]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; TRAPP complex [GO:0030008]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]	cis-Golgi network membrane [GO:0033106]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; TRAPP complex [GO:0030008]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]	endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]	COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]	cis-Golgi network membrane [GO:0033106]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; TRAPP complex [GO:0030008]	cis-Golgi network membrane [GO:0033106]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; TRAPP complex [GO:0030008]		
d1wc9a__d3laic___1	Metazoa		Chordata	Firmicutes	cis-Golgi network membrane [GO:0033106]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; TRAPP complex [GO:0030008]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]	signal transduction [GO:0007165]	cis-Golgi network membrane [GO:0033106]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; TRAPP complex [GO:0030008]	integral component of membrane [GO:0016021]		heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1wcba1_d3naal1__1												
d1wcbb1_d1dqjb2__1		Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1wcfa1_d3fq3a___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1wcga1_d1wzlb3__1	Metazoa		Arthropoda	Firmicutes	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d1wcgb__d3apgb1__1	Metazoa		Arthropoda	Euryarchaeota	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1wcha__d1fq1a___1	Metazoa	Metazoa	Chordata	Chordata	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1wcib2_d2c42b3__1	Metazoa		Chordata	Proteobacteria	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	electron transport chain [GO:0022900]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	cytoplasm [GO:0005737]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d1wcqa2_d1p8je1__1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	metabolic process [GO:0008152]	dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	extracellular region [GO:0005576]	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d1wcqb3_d1z4wa___1			Actinobacteria	Negarnaviricota	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; viral budding from plasma membrane [GO:0046761]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	metabolic process [GO:0008152]	viral budding from plasma membrane [GO:0046761]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d1wcqc2_d2vzoa1__1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	metabolic process [GO:0008152]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1wcqc2_d3vd4c1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	metabolic process [GO:0008152]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1wcrb__d2e2ab___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity [GO:0090566]; N,N'-diacetylchitobiose import [GO:1902815]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; protein homooligomerization [GO:0051260]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	N,N'-diacetylchitobiose import [GO:1902815]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; protein homooligomerization [GO:0051260]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity [GO:0090566]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d1wcsa1_d5gm3a___1		Fungi		Ascomycota	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	cellulase activity [GO:0008810]
d1wcsa2_d4b7rb___1				Negarnaviricota	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d1wcua1_d2orxa1__1	Fungi	Metazoa	Chytridiomycota	Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome [GO:0005769]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; sorting endosome [GO:0097443]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; axon extension involved in axon guidance [GO:0048846]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sensory neuron axon guidance [GO:0097374]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]		actin cytoskeleton reorganization [GO:0031532]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sensory neuron axon guidance [GO:0097374]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]		axon [GO:0030424]; cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome [GO:0005769]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; sorting endosome [GO:0097443]		GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d1wcya2_d3i2ha1__1	Metazoa		Chordata	Actinobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cocaine catabolic process [GO:0050784]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]
d1wcyb2_d2hl6b___1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]; cell wall macromolecule catabolic process [GO:0016998]; cellulose catabolic process [GO:0030245]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellulose catabolic process [GO:0030245]; cell wall macromolecule catabolic process [GO:0016998]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]
d1wd0a__d1bnza___1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]	DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]
d1wd3a1_d2d43a1__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; arabinose metabolic process [GO:0019566]; L-arabinose metabolic process [GO:0046373]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; arabinose metabolic process [GO:0019566]; L-arabinose metabolic process [GO:0046373]; xylan catabolic process [GO:0045493]	arabinan catabolic process [GO:0031222]; arabinose metabolic process [GO:0019566]; L-arabinose metabolic process [GO:0046373]; xylan catabolic process [GO:0045493]	arabinan catabolic process [GO:0031222]; arabinose metabolic process [GO:0019566]; L-arabinose metabolic process [GO:0046373]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	alpha-L-arabinofuranosidase activity [GO:0046556]	alpha-L-arabinofuranosidase activity [GO:0046556]
d1wd3a1_d5kxda___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; arabinose metabolic process [GO:0019566]; L-arabinose metabolic process [GO:0046373]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]	arabinan catabolic process [GO:0031222]; arabinose metabolic process [GO:0019566]; L-arabinose metabolic process [GO:0046373]; xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]		alpha-L-arabinofuranosidase activity [GO:0046556]	carbohydrate binding [GO:0030246]
d1wdaa3_d1lxyb___1	Metazoa		Chordata	Tenericutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; arginine binding [GO:0034618]; arginine deiminase activity [GO:0016990]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular protein modification process [GO:0006464]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; innate immune response [GO:0045087]; nucleosome assembly [GO:0006334]; protein citrullination [GO:0018101]; stem cell population maintenance [GO:0019827]	cytoplasm [GO:0005737]; arginine deiminase activity [GO:0016990]; arginine catabolic process to ornithine [GO:0019547]	cellular protein modification process [GO:0006464]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; innate immune response [GO:0045087]; nucleosome assembly [GO:0006334]; protein citrullination [GO:0018101]; stem cell population maintenance [GO:0019827]	arginine catabolic process to ornithine [GO:0019547]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; arginine deiminase activity [GO:0016990]; calcium ion binding [GO:0005509]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]	arginine deiminase activity [GO:0016990]
d1wdcb__d3lk0b___1	Metazoa	Metazoa	Mollusca	Chordata	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]		astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1wdcc__d5csna1__1	Metazoa	Metazoa	Mollusca	Chordata	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]		astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1wdda2_d5hati1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1wdde2_d3wqph1__1	Viridiplantae		Streptophyta	Euryarchaeota	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1wdds__d5iu0i___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast membrane [GO:0031969]; chloroplast stroma [GO:0009570]; plastid [GO:0009536]; thylakoid [GO:0009579]; monooxygenase activity [GO:0004497]; protein domain specific binding [GO:0019904]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]; response to blue light [GO:0009637]; response to far red light [GO:0010218]; response to red light [GO:0010114]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]; response to blue light [GO:0009637]; response to far red light [GO:0010218]; response to red light [GO:0010114]	chloroplast [GO:0009507]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast membrane [GO:0031969]; chloroplast stroma [GO:0009570]; plastid [GO:0009536]; thylakoid [GO:0009579]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; protein domain specific binding [GO:0019904]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d1wdjb__d4mk5a1__1			Deinococcus-Thermus	Negarnaviricota		host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cap snatching [GO:0075526]; suppression by virus of host RNA polymerase II activity [GO:0039523]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]		cap snatching [GO:0075526]; suppression by virus of host RNA polymerase II activity [GO:0039523]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]		host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d1wdkb1_d4pzeg2__1			Proteobacteria	Proteobacteria	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	fatty acid beta-oxidation [GO:0006635]	fatty acid metabolic process [GO:0006631]	fatty acid beta-oxidation multienzyme complex [GO:0036125]		3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d1wdkb3_d1n1ea2__1			Proteobacteria		fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycosome [GO:0020015]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]	fatty acid beta-oxidation [GO:0006635]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycosome [GO:0020015]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]
d1wdkb4_d1ey3c___1		Metazoa	Proteobacteria	Chordata	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	fatty acid beta-oxidation [GO:0006635]	fatty acid beta-oxidation [GO:0006635]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]
d1wdkc2_d1dd8a2__1			Proteobacteria	Proteobacteria	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid beta-oxidation [GO:0006635]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	cytosol [GO:0005829]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1wdkd1_d1oeqb4__1			Proteobacteria		fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation multienzyme complex [GO:0036125]		3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	
d1wdkd1_d1ulqd2__1			Proteobacteria	Deinococcus-Thermus	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation multienzyme complex [GO:0036125]		3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1wdkd2_d1kasa1__1			Proteobacteria	Proteobacteria	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation [GO:0006635]	fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	cytosol [GO:0005829]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1wdla4_d1wz8b___1			Proteobacteria	Deinococcus-Thermus	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	catalytic activity [GO:0003824]	fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation multienzyme complex [GO:0036125]		3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	catalytic activity [GO:0003824]
d1wdlb2_d5je8b2__1			Proteobacteria	Firmicutes	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation multienzyme complex [GO:0036125]		3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1wdlb4_d1szoi___1			Proteobacteria	Actinobacteria	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation multienzyme complex [GO:0036125]		3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]
d1wdlc2_d2vu2c2__1			Proteobacteria	Proteobacteria	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid beta-oxidation [GO:0006635]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	cytoplasm [GO:0005737]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1wdld2_d2vb9c2__1			Proteobacteria	Proteobacteria	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid beta-oxidation [GO:0006635]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	cytosol [GO:0005829]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1wdma4_d1yg8c___1			Proteobacteria	Proteobacteria	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	fatty acid beta-oxidation [GO:0006635]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1wdmc2_d1ub7a2__1			Proteobacteria	Deinococcus-Thermus	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation [GO:0006635]	fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	cytoplasm [GO:0005737]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d1wdta1_d1eloa1__1			Deinococcus-Thermus	Deinococcus-Thermus	GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1wdta4_d1zm3c4__1			Deinococcus-Thermus	Proteobacteria	GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]					GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d1wdta4_d1zm4a4__1			Deinococcus-Thermus	Proteobacteria	GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]					GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d1wdwb__d2c2bf___1		Viridiplantae	Euryarchaeota	Streptophyta	tryptophan synthase activity [GO:0004834]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]; threonine biosynthetic process [GO:0009088]		threonine biosynthetic process [GO:0009088]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	tryptophan synthase activity [GO:0004834]	pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]
d1wdya__d3eu9c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; ATP binding [GO:0005524]; endoribonuclease activity [GO:0004521]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; RNA binding [GO:0003723]; defense response to virus [GO:0051607]; mRNA processing [GO:0006397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; type I interferon signaling pathway [GO:0060337]	aggresome [GO:0016235]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle membrane [GO:0030659]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; presynaptic membrane [GO:0042734]; identical protein binding [GO:0042802]; magnesium ion transmembrane transporter activity [GO:0015095]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; lipoprotein transport [GO:0042953]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345]	defense response to virus [GO:0051607]; mRNA processing [GO:0006397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; type I interferon signaling pathway [GO:0060337]	lipoprotein transport [GO:0042953]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]	aggresome [GO:0016235]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle membrane [GO:0030659]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; presynaptic membrane [GO:0042734]	ATP binding [GO:0005524]; endoribonuclease activity [GO:0004521]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; RNA binding [GO:0003723]	identical protein binding [GO:0042802]; magnesium ion transmembrane transporter activity [GO:0015095]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]
d1we0a1_d3hvxb___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]
d1we0b__d1ev9c2__1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]; aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]
d1we0d__d2v41e___1		Metazoa	Firmicutes	Annelida	cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	peroxiredoxin activity [GO:0051920]
d1we0f__d3zrda1__1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	thioredoxin peroxidase activity [GO:0008379]
d1we0g__d2gssb2__1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1we0j__d3zvja___1		Metazoa	Firmicutes	Platyhelminthes	cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1we1b__d1j77a___1			Cyanobacteria	Proteobacteria	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; photosynthesis [GO:0015979]; response to oxidative stress [GO:0006979]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; photosynthesis [GO:0015979]; response to oxidative stress [GO:0006979]	heme oxidation [GO:0006788]			heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d1we1c__d4g8ua___1		Metazoa	Cyanobacteria	Chordata	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; photosynthesis [GO:0015979]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; photosynthesis [GO:0015979]; response to oxidative stress [GO:0006979]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]		caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1we1d__d4wmha___1		Metazoa	Cyanobacteria	Chordata	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; photosynthesis [GO:0015979]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; photosynthesis [GO:0015979]; response to oxidative stress [GO:0006979]	cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d1we3b2_d1aonl2__1				Proteobacteria		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d1we3c2_d1xckg3__1				Proteobacteria		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]		'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]
d1we3e2_d1q3sb2__1				Euryarchaeota		ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]		protein folding [GO:0006457]				ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1we3k2_d1kp8b2__1				Proteobacteria		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]		'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]
d1we3m2_d1j4ze2__1												
d1we3o__d1p3hc___1				Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; zymogen binding [GO:0035375]; cellular response to heat [GO:0034605]; chaperone cofactor-dependent protein refolding [GO:0051085]; regulation of transcription, DNA-templated [GO:0006355]; response to antibiotic [GO:0046677]; response to heat [GO:0009408]		cellular response to heat [GO:0034605]; chaperone cofactor-dependent protein refolding [GO:0051085]; regulation of transcription, DNA-templated [GO:0006355]; response to antibiotic [GO:0046677]; response to heat [GO:0009408]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; zymogen binding [GO:0035375]
d1we3t__d2c7ds1__1				Proteobacteria		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d1wega__d1nkua___1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]			4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]
d1wejh2_d1ruph1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1wejl1_d2bobb2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1wejl2_d1fyte2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1wejl2_d5x2qk1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; G protein-coupled receptor activity [GO:0004930]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		G protein-coupled receptor activity [GO:0004930]
d1wela1_d2dgsa1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; RNA binding [GO:0003723]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(G) binding [GO:0034046]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; RNA stem-loop binding [GO:0035613]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; maternal placenta development [GO:0001893]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; spermatogenesis [GO:0007283]		cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; maternal placenta development [GO:0001893]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; spermatogenesis [GO:0007283]	nucleoplasm [GO:0005654]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]	RNA binding [GO:0003723]	mRNA 3'-UTR binding [GO:0003730]; poly(G) binding [GO:0034046]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; RNA stem-loop binding [GO:0035613]
d1wexa1_d3p5tq___1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; mRNA binding [GO:0003729]; mRNA processing [GO:0006397]; positive regulation of RNA splicing [GO:0033120]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	mRNA processing [GO:0006397]; positive regulation of RNA splicing [GO:0033120]	messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	mRNA binding [GO:0003729]	exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]
d1wf0a1_d5tbxb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; interchromatin granule [GO:0035061]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; DNA-binding transcription factor activity [GO:0003700]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; mRNA 3'-UTR binding [GO:0003730]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA processing [GO:0006397]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; nuclear inner membrane organization [GO:0071765]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein import into nucleus [GO:0042307]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of protein stability [GO:0031647]; response to endoplasmic reticulum stress [GO:0034976]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; translation repressor activity [GO:0030371]; mRNA stabilization [GO:0048255]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of translation [GO:0045727]; response to cold [GO:0009409]; response to UV [GO:0009411]; stress granule assembly [GO:0034063]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA processing [GO:0006397]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; nuclear inner membrane organization [GO:0071765]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein import into nucleus [GO:0042307]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of protein stability [GO:0031647]; response to endoplasmic reticulum stress [GO:0034976]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]; transcription by RNA polymerase II [GO:0006366]	mRNA stabilization [GO:0048255]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of translation [GO:0045727]; response to cold [GO:0009409]; response to UV [GO:0009411]; stress granule assembly [GO:0034063]	cytoplasmic stress granule [GO:0010494]; interchromatin granule [GO:0035061]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	DNA-binding transcription factor activity [GO:0003700]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; mRNA 3'-UTR binding [GO:0003730]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]	mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; translation repressor activity [GO:0030371]
d1wf2a1_d1s79a1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; identical protein binding [GO:0042802]; mRNA 3'-UTR binding [GO:0003730]; N6-methyladenosine-containing RNA binding [GO:1990247]; nucleosomal DNA binding [GO:0031492]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; telomerase RNA binding [GO:0070034]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; ATP-dependent chromatin remodeling [GO:0043044]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of telomere maintenance via telomerase [GO:0032211]; osteoblast differentiation [GO:0001649]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	cytoplasm [GO:0005737]; nuclear chromosome, telomeric region [GO:0000784]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049]; histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	3'-UTR-mediated mRNA stabilization [GO:0070935]; ATP-dependent chromatin remodeling [GO:0043044]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of telomere maintenance via telomerase [GO:0032211]; osteoblast differentiation [GO:0001649]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	actin cytoskeleton [GO:0015629]; catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]	cytoplasm [GO:0005737]; nuclear chromosome, telomeric region [GO:0000784]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	identical protein binding [GO:0042802]; mRNA 3'-UTR binding [GO:0003730]; N6-methyladenosine-containing RNA binding [GO:1990247]; nucleosomal DNA binding [GO:0031492]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; telomerase RNA binding [GO:0070034]	mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049]
d1wf3a1_d1rw4a___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosomal small subunit binding [GO:0043024]; small ribosomal subunit rRNA binding [GO:0070181]; ribosomal small subunit assembly [GO:0000028]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	ribosomal small subunit assembly [GO:0000028]	nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	molybdenum-iron nitrogenase complex [GO:0016612]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosomal small subunit binding [GO:0043024]; small ribosomal subunit rRNA binding [GO:0070181]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1wf4c2_d1kpop2__1												
d1wf4e2_d1kpou2__1												
d1wf4k2_d1pcqi2__1				Proteobacteria		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; response to heat [GO:0009408]; virion assembly [GO:0019068]		cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d1wf4p__d1jh2h___1												
d1wfda1_d5fvla1__1	Metazoa	Fungi	Chordata	Ascomycota	extrinsic component of membrane [GO:0019898]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; midbody [GO:0030496]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; midbody abscission [GO:0061952]; mitotic cytokinesis [GO:0000281]; negative regulation of protein binding [GO:0032091]	cell [GO:0005623]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; ESCRT IV complex [GO:1990621]; membrane [GO:0016020]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; intralumenal vesicle formation [GO:0070676]; late endosome to vacuole transport [GO:0045324]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein transport [GO:0015031]; sterol metabolic process [GO:0016125]; vacuole organization [GO:0007033]	midbody abscission [GO:0061952]; mitotic cytokinesis [GO:0000281]; negative regulation of protein binding [GO:0032091]	intralumenal vesicle formation [GO:0070676]; late endosome to vacuole transport [GO:0045324]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein transport [GO:0015031]; sterol metabolic process [GO:0016125]; vacuole organization [GO:0007033]	extrinsic component of membrane [GO:0019898]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; midbody [GO:0030496]	cell [GO:0005623]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; ESCRT IV complex [GO:1990621]; membrane [GO:0016020]; nucleus [GO:0005634]	phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1wfja1_d4ns0a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	RNA binding [GO:0003723]; defense response [GO:0006952]	cell junction [GO:0030054]; cholinergic synapse [GO:0098981]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extrinsic component of membrane [GO:0019898]; extrinsic component of synaptic vesicle membrane [GO:0098850]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphate ion binding [GO:0042301]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; selenium binding [GO:0008430]; zinc ion binding [GO:0008270]; brain development [GO:0007420]; dendritic spine organization [GO:0097061]; intracellular protein transport [GO:0006886]; regulation of NMDA receptor activity [GO:2000310]	defense response [GO:0006952]	brain development [GO:0007420]; dendritic spine organization [GO:0097061]; intracellular protein transport [GO:0006886]; regulation of NMDA receptor activity [GO:2000310]		cell junction [GO:0030054]; cholinergic synapse [GO:0098981]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extrinsic component of membrane [GO:0019898]; extrinsic component of synaptic vesicle membrane [GO:0098850]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]	RNA binding [GO:0003723]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphate ion binding [GO:0042301]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; selenium binding [GO:0008430]; zinc ion binding [GO:0008270]
d1wfma1_d5bzzb2__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; exocytic vesicle [GO:0070382]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; clathrin binding [GO:0030276]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; ubiquitin-specific protease binding [GO:1990381]; adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192]	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	axon [GO:0030424]; exocytic vesicle [GO:0070382]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; clathrin binding [GO:0030276]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]	anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381]
d1wfqa1_d3nenb1__1	Metazoa		Chordata	Euryarchaeota	CRD-mediated mRNA stability complex [GO:0070937]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; RNA binding [GO:0003723]; male gonad development [GO:0008584]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	male gonad development [GO:0008584]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]	aspartyl-tRNA aminoacylation [GO:0006422]	CRD-mediated mRNA stability complex [GO:0070937]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]	RNA binding [GO:0003723]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d1wfua1_d2arwa___1	Metazoa	Metazoa	Chordata	Chordata	chromatin [GO:0000785]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; ciliary neurotrophic factor receptor complex [GO:0070110]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor binding [GO:0070119]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; enzyme binding [GO:0019899]; interleukin-6 binding [GO:0019981]; interleukin-6 receptor activity [GO:0004915]; protein homodimerization activity [GO:0042803]; acute-phase response [GO:0006953]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; endocrine pancreas development [GO:0031018]; extrinsic apoptotic signaling pathway [GO:0097191]; hepatic immune response [GO:0002384]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of interleukin-8 production [GO:0032717]; neutrophil mediated immunity [GO:0002446]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of glomerular mesangial cell proliferation [GO:0072126]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to cytokine [GO:0034097]	negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]	acute-phase response [GO:0006953]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; endocrine pancreas development [GO:0031018]; extrinsic apoptotic signaling pathway [GO:0097191]; hepatic immune response [GO:0002384]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of interleukin-8 production [GO:0032717]; neutrophil mediated immunity [GO:0002446]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of glomerular mesangial cell proliferation [GO:0072126]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to cytokine [GO:0034097]	chromatin [GO:0000785]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; ciliary neurotrophic factor receptor complex [GO:0070110]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ciliary neurotrophic factor binding [GO:0070119]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; enzyme binding [GO:0019899]; interleukin-6 binding [GO:0019981]; interleukin-6 receptor activity [GO:0004915]; protein homodimerization activity [GO:0042803]
d1wfva1_d3dj3a___1	Metazoa	Metazoa	Chordata	Chordata	bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; late endosome [GO:0005770]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; synapse [GO:0045202]; beta-1 adrenergic receptor binding [GO:0031697]; phosphatase binding [GO:0019902]; receptor signaling complex adaptor activity [GO:0030159]; SMAD binding [GO:0046332]; type II activin receptor binding [GO:0070699]; cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]; activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]	activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; late endosome [GO:0005770]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; synapse [GO:0045202]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	beta-1 adrenergic receptor binding [GO:0031697]; phosphatase binding [GO:0019902]; receptor signaling complex adaptor activity [GO:0030159]; SMAD binding [GO:0046332]; type II activin receptor binding [GO:0070699]	beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]
d1wg3a1_d2i32b___1	Fungi	Metazoa	Ascomycota	Chordata	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleus [GO:0005634]; histone binding [GO:0042393]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H2B ubiquitination [GO:0033523]; nucleosome disassembly [GO:0006337]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of gene expression [GO:0010468]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; DNA repair [GO:0006281]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; muscle cell differentiation [GO:0042692]; negative regulation of chromatin silencing [GO:0031936]; nucleosome assembly [GO:0006334]; osteoblast differentiation [GO:0001649]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H2B ubiquitination [GO:0033523]; nucleosome disassembly [GO:0006337]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of gene expression [GO:0010468]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]	DNA repair [GO:0006281]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; muscle cell differentiation [GO:0042692]; negative regulation of chromatin silencing [GO:0031936]; nucleosome assembly [GO:0006334]; osteoblast differentiation [GO:0001649]	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleus [GO:0005634]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	histone binding [GO:0042393]	chromatin binding [GO:0003682]; histone binding [GO:0042393]
d1wg6a1_d2v90e___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; nuclear body [GO:0016604]; protein-containing complex [GO:0032991]; phosphatidylinositol binding [GO:0035091]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; protein localization [GO:0008104]	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytosol [GO:0005829]; subapical complex [GO:0035003]; guanylate cyclase inhibitor activity [GO:0030251]; ion channel inhibitor activity [GO:0008200]; protein C-terminus binding [GO:0008022]; ubiquitin-specific protease binding [GO:1990381]; ion transport [GO:0006811]; negative regulation of cGMP-mediated signaling [GO:0010754]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to toxic substance [GO:0009636]; water transport [GO:0006833]	cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; protein localization [GO:0008104]	ion transport [GO:0006811]; negative regulation of cGMP-mediated signaling [GO:0010754]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to toxic substance [GO:0009636]; water transport [GO:0006833]	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; nuclear body [GO:0016604]; protein-containing complex [GO:0032991]	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytosol [GO:0005829]; subapical complex [GO:0035003]	phosphatidylinositol binding [GO:0035091]	guanylate cyclase inhibitor activity [GO:0030251]; ion channel inhibitor activity [GO:0008200]; protein C-terminus binding [GO:0008022]; ubiquitin-specific protease binding [GO:1990381]
d1wgfa1_d1hrza___1	Metazoa	Metazoa	Chordata	Chordata	fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]; RNA polymerase I upstream control element sequence-specific DNA binding [GO:0001165]; scaffold protein binding [GO:0097110]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin silencing at rDNA [GO:0000183]; positive regulation of transcription by RNA polymerase I [GO:0045943]; transcription by RNA polymerase I [GO:0006360]; transcription elongation from RNA polymerase I promoter [GO:0006362]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; calmodulin binding [GO:0005516]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; transcription factor binding [GO:0008134]; cell differentiation [GO:0030154]; male sex determination [GO:0030238]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of male gonad development [GO:2000020]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; sex differentiation [GO:0007548]	cellular response to leukemia inhibitory factor [GO:1990830]; chromatin silencing at rDNA [GO:0000183]; positive regulation of transcription by RNA polymerase I [GO:0045943]; transcription by RNA polymerase I [GO:0006360]; transcription elongation from RNA polymerase I promoter [GO:0006362]	cell differentiation [GO:0030154]; male sex determination [GO:0030238]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of male gonad development [GO:2000020]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; sex differentiation [GO:0007548]	fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]; RNA polymerase I upstream control element sequence-specific DNA binding [GO:0001165]; scaffold protein binding [GO:0097110]	calmodulin binding [GO:0005516]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; transcription factor binding [GO:0008134]
d1wgja__d2ik0b___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1wgjb__d4z74j1__1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1wgka1_d1sf0a___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; sulfur carrier activity [GO:0097163]; protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble uridine modification [GO:0002098]	nucleotide binding [GO:0000166]	protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble uridine modification [GO:0002098]		cytosol [GO:0005829]		sulfur carrier activity [GO:0097163]	nucleotide binding [GO:0000166]
d1wgqa1_d1w1ga1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; metal ion binding [GO:0046872]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]	actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	metal ion binding [GO:0046872]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]	3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]
d1wgua1_d1gc6a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; amyloid-beta binding [GO:0001540]; histone acetyltransferase binding [GO:0035035]; transcription factor binding [GO:0008134]; actin filament-based movement [GO:0030048]; axon guidance [GO:0007411]; cell cycle arrest [GO:0007050]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; neuron migration [GO:0001764]; positive regulation of apoptotic process [GO:0043065]; protein stabilization [GO:0050821]; regulation of transcription, DNA-templated [GO:0006355]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin filament-based movement [GO:0030048]; axon guidance [GO:0007411]; cell cycle arrest [GO:0007050]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; neuron migration [GO:0001764]; positive regulation of apoptotic process [GO:0043065]; protein stabilization [GO:0050821]; regulation of transcription, DNA-templated [GO:0006355]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	amyloid-beta binding [GO:0001540]; histone acetyltransferase binding [GO:0035035]; transcription factor binding [GO:0008134]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d1wgua1_d1m7ec___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; amyloid-beta binding [GO:0001540]; histone acetyltransferase binding [GO:0035035]; transcription factor binding [GO:0008134]; actin filament-based movement [GO:0030048]; axon guidance [GO:0007411]; cell cycle arrest [GO:0007050]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; neuron migration [GO:0001764]; positive regulation of apoptotic process [GO:0043065]; protein stabilization [GO:0050821]; regulation of transcription, DNA-templated [GO:0006355]	apical plasma membrane [GO:0016324]; clathrin coat of coated pit [GO:0030132]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]; activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	actin filament-based movement [GO:0030048]; axon guidance [GO:0007411]; cell cycle arrest [GO:0007050]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; neuron migration [GO:0001764]; positive regulation of apoptotic process [GO:0043065]; protein stabilization [GO:0050821]; regulation of transcription, DNA-templated [GO:0006355]	activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	apical plasma membrane [GO:0016324]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; histone acetyltransferase binding [GO:0035035]; transcription factor binding [GO:0008134]	AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol binding [GO:0035091]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]
d1wgwa1_d1j8yf1__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]; 7S RNA binding [GO:0008312]; drug binding [GO:0008144]; endoplasmic reticulum signal peptide binding [GO:0030942]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribonucleoprotein complex binding [GO:0043021]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]	signal recognition particle [GO:0048500]	7S RNA binding [GO:0008312]; drug binding [GO:0008144]; endoplasmic reticulum signal peptide binding [GO:0030942]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribonucleoprotein complex binding [GO:0043021]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1wh0a1_d5ds2b___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; Hsp90 protein binding [GO:0051879]; Lys48-specific deubiquitinase activity [GO:1990380]; metal ion binding [GO:0046872]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin protein ligase binding [GO:0031625]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of skeletal muscle tissue development [GO:0048642]; positive regulation of cell cycle process [GO:0090068]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of cellular response to hypoxia [GO:1900037]; regulation of ERAD pathway [GO:1904292]; regulation of protein stability [GO:0031647]; response to endoplasmic reticulum stress [GO:0034976]; ubiquitin-dependent ERAD pathway [GO:0030433]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]	negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of skeletal muscle tissue development [GO:0048642]; positive regulation of cell cycle process [GO:0090068]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of cellular response to hypoxia [GO:1900037]; regulation of ERAD pathway [GO:1904292]; regulation of protein stability [GO:0031647]; response to endoplasmic reticulum stress [GO:0034976]; ubiquitin-dependent ERAD pathway [GO:0030433]	protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	Hsp90 protein binding [GO:0051879]; Lys48-specific deubiquitinase activity [GO:1990380]; metal ion binding [GO:0046872]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]
d1wh1a1_d5e22b1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasm [GO:0005737]; neuromuscular junction [GO:0031594]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]	neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567]		cell junction [GO:0030054]; cytoplasm [GO:0005737]; neuromuscular junction [GO:0031594]		ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]
d1wh3a1_d1ef5a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; RNA binding [GO:0003723]; thyroid hormone receptor binding [GO:0046966]; transferase activity [GO:0016740]; defense response to virus [GO:0051607]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of viral genome replication [GO:0045071]; regulation of ribonuclease activity [GO:0060700]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	Ral guanyl-nucleotide exchange factor activity [GO:0008321]; small GTPase mediated signal transduction [GO:0007264]	defense response to virus [GO:0051607]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of viral genome replication [GO:0045071]; regulation of ribonuclease activity [GO:0060700]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	small GTPase mediated signal transduction [GO:0007264]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; RNA binding [GO:0003723]; thyroid hormone receptor binding [GO:0046966]; transferase activity [GO:0016740]	Ral guanyl-nucleotide exchange factor activity [GO:0008321]
d1wh4a1_d2p1ha2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]; ATP binding [GO:0005524]; interleukin-1 receptor binding [GO:0005149]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of smooth muscle cell proliferation [GO:0048661]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of smooth muscle cell proliferation [GO:0048661]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; interleukin-1 receptor binding [GO:0005149]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d1whda1_d3stjl2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; GTPase activator activity [GO:0005096]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; signal transduction [GO:0007165]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; signal transduction [GO:0007165]	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]	GTPase activator activity [GO:0005096]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]
d1whla1_d2e4ha___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; microtubule [GO:0005874]; perinuclear region of cytoplasm [GO:0048471]; spindle [GO:0005819]; Lys48-specific deubiquitinase activity [GO:1990380]; Lys63-specific deubiquitinase activity [GO:0061578]; proline-rich region binding [GO:0070064]; protein kinase binding [GO:0019901]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell cycle [GO:0007049]; homeostasis of number of cells [GO:0048872]; innate immune response [GO:0045087]; necroptotic process [GO:0070266]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of JNK cascade [GO:0046329]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of type I interferon production [GO:0032480]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of cellular protein localization [GO:1903829]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536]; protein linear deubiquitination [GO:1990108]; regulation of B cell differentiation [GO:0045577]; regulation of cilium assembly [GO:1902017]; regulation of inflammatory response [GO:0050727]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of mitotic cell cycle [GO:0007346]; regulation of necroptotic process [GO:0060544]; regulation of protein binding [GO:0043393]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; ripoptosome assembly involved in necroptotic process [GO:1901026]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; intermediate filament [GO:0005882]; kinetochore [GO:0000776]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nuclear envelope [GO:0005635]; ruffle [GO:0001726]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116]; protein transport into plasma membrane raft [GO:0044861]	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell cycle [GO:0007049]; homeostasis of number of cells [GO:0048872]; innate immune response [GO:0045087]; necroptotic process [GO:0070266]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of JNK cascade [GO:0046329]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of type I interferon production [GO:0032480]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of cellular protein localization [GO:1903829]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536]; protein linear deubiquitination [GO:1990108]; regulation of B cell differentiation [GO:0045577]; regulation of cilium assembly [GO:1902017]; regulation of inflammatory response [GO:0050727]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of mitotic cell cycle [GO:0007346]; regulation of necroptotic process [GO:0060544]; regulation of protein binding [GO:0043393]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; ripoptosome assembly involved in necroptotic process [GO:1901026]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116]; protein transport into plasma membrane raft [GO:0044861]	centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; microtubule [GO:0005874]; perinuclear region of cytoplasm [GO:0048471]; spindle [GO:0005819]	centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; intermediate filament [GO:0005882]; kinetochore [GO:0000776]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nuclear envelope [GO:0005635]; ruffle [GO:0001726]	Lys48-specific deubiquitinase activity [GO:1990380]; Lys63-specific deubiquitinase activity [GO:0061578]; proline-rich region binding [GO:0070064]; protein kinase binding [GO:0019901]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270]
d1whoa__d1bmwa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]	extracellular region [GO:0005576]			extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d1whs.1_d2qoea2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	serine-type carboxypeptidase activity [GO:0004185]; proteolysis involved in cellular protein catabolic process [GO:0051603]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	proteolysis involved in cellular protein catabolic process [GO:0051603]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	serine-type carboxypeptidase activity [GO:0004185]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1whwa1_d1u1ra2__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA binding [GO:0003723]; mRNA cis splicing, via spliceosome [GO:0045292]; multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	mRNA cis splicing, via spliceosome [GO:0045292]; multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	RNA binding [GO:0003723]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]
d1wi0a1_d2nptb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; spindle [GO:0005819]; ATP binding [GO:0005524]; MAP kinase kinase activity [GO:0004708]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; activation of MAPK activity [GO:0000187]; activation of protein kinase activity [GO:0032147]; cellular response to growth factor stimulus [GO:0071363]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000342]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; spindle [GO:0005819]; ATP binding [GO:0005524]; MAP kinase kinase activity [GO:0004708]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; activation of MAPK activity [GO:0000187]; activation of protein kinase activity [GO:0032147]; cellular response to growth factor stimulus [GO:0071363]; cellular response to laminar fluid shear stress [GO:0071499]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000342]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription by RNA polymerase II [GO:0045944]; signal transduction [GO:0007165]; signal transduction by protein phosphorylation [GO:0023014]	activation of MAPK activity [GO:0000187]; activation of protein kinase activity [GO:0032147]; cellular response to growth factor stimulus [GO:0071363]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000342]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; signal transduction by protein phosphorylation [GO:0023014]	activation of MAPK activity [GO:0000187]; activation of protein kinase activity [GO:0032147]; cellular response to growth factor stimulus [GO:0071363]; cellular response to laminar fluid shear stress [GO:0071499]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000342]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription by RNA polymerase II [GO:0045944]; signal transduction [GO:0007165]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; spindle [GO:0005819]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; spindle [GO:0005819]	ATP binding [GO:0005524]; MAP kinase kinase activity [GO:0004708]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]	ATP binding [GO:0005524]; MAP kinase kinase activity [GO:0004708]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]
d1wi1a1_d5najb___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; presynapse [GO:0098793]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; dense core granule exocytosis [GO:1990504]; exocytosis [GO:0006887]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; synaptic vesicle exocytosis [GO:0016079]	cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; synapse [GO:0045202]; actin binding [GO:0003779]; profilin binding [GO:0005522]; SH3 domain binding [GO:0017124]; WW domain binding [GO:0050699]; actin polymerization or depolymerization [GO:0008154]; actin polymerization-dependent cell motility [GO:0070358]; axon guidance [GO:0007411]	dense core granule exocytosis [GO:1990504]; exocytosis [GO:0006887]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; synaptic vesicle exocytosis [GO:0016079]	actin polymerization-dependent cell motility [GO:0070358]; actin polymerization or depolymerization [GO:0008154]; axon guidance [GO:0007411]	cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; presynapse [GO:0098793]	cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; synapse [GO:0045202]	lipid binding [GO:0008289]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]	actin binding [GO:0003779]; profilin binding [GO:0005522]; SH3 domain binding [GO:0017124]; WW domain binding [GO:0050699]
d1wi4a1_d3l4fd1__1	Metazoa	Metazoa	Chordata	Chordata	phagocytic vesicle [GO:0045335]; syntaxin binding [GO:0019905]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to interferon-gamma [GO:0071346]; insulin receptor signaling pathway [GO:0008286]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of keratinocyte proliferation [GO:0010838]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; regulation of glucose transmembrane transport [GO:0010827]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	cell [GO:0005623]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; ionotropic glutamate receptor complex [GO:0008328]; neuron projection [GO:0043005]; neuron spine [GO:0044309]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; ankyrin repeat binding [GO:0071532]; GKAP/Homer scaffold activity [GO:0030160]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; protein C-terminus binding [GO:0008022]; protein-containing complex binding [GO:0044877]; receptor signaling complex adaptor activity [GO:0030159]; scaffold protein binding [GO:0097110]; SH3 domain binding [GO:0017124]; somatostatin receptor binding [GO:0031877]; adult behavior [GO:0030534]; associative learning [GO:0008306]; brain morphogenesis [GO:0048854]; cytoskeletal anchoring at plasma membrane [GO:0007016]; dendritic spine morphogenesis [GO:0060997]; determination of affect [GO:0050894]; habituation [GO:0046959]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; negative regulation of actin filament bundle assembly [GO:0032232]; neuromuscular process controlling balance [GO:0050885]; olfactory behavior [GO:0042048]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density assembly [GO:0097107]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; regulation of AMPA receptor activity [GO:2000311]; righting reflex [GO:0060013]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; synaptic growth at neuromuscular junction [GO:0051124]; vocalization behavior [GO:0071625]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to interferon-gamma [GO:0071346]; insulin receptor signaling pathway [GO:0008286]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of keratinocyte proliferation [GO:0010838]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; regulation of glucose transmembrane transport [GO:0010827]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	adult behavior [GO:0030534]; associative learning [GO:0008306]; brain morphogenesis [GO:0048854]; cytoskeletal anchoring at plasma membrane [GO:0007016]; dendritic spine morphogenesis [GO:0060997]; determination of affect [GO:0050894]; habituation [GO:0046959]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; negative regulation of actin filament bundle assembly [GO:0032232]; neuromuscular process controlling balance [GO:0050885]; olfactory behavior [GO:0042048]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density assembly [GO:0097107]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; regulation of AMPA receptor activity [GO:2000311]; righting reflex [GO:0060013]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; synaptic growth at neuromuscular junction [GO:0051124]; vocalization behavior [GO:0071625]	phagocytic vesicle [GO:0045335]	cell [GO:0005623]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; ionotropic glutamate receptor complex [GO:0008328]; neuron projection [GO:0043005]; neuron spine [GO:0044309]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]	syntaxin binding [GO:0019905]	ankyrin repeat binding [GO:0071532]; GKAP/Homer scaffold activity [GO:0030160]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; receptor signaling complex adaptor activity [GO:0030159]; scaffold protein binding [GO:0097110]; SH3 domain binding [GO:0017124]; somatostatin receptor binding [GO:0031877]
d1wi5a1_d3kx2b5__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small-subunit processome [GO:0032040]; RNA binding [GO:0003723]; transcription factor binding [GO:0008134]; mRNA processing [GO:0006397]; rRNA processing [GO:0006364]	90S preribosome [GO:0030686]; mitochondrion [GO:0005739]; post-mRNA release spliceosomal complex [GO:0071014]; ATP binding [GO:0005524]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; maturation of SSU-rRNA [GO:0030490]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; spliceosomal complex disassembly [GO:0000390]	mRNA processing [GO:0006397]; rRNA processing [GO:0006364]	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; maturation of SSU-rRNA [GO:0030490]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; spliceosomal complex disassembly [GO:0000390]	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; small-subunit processome [GO:0032040]	90S preribosome [GO:0030686]; mitochondrion [GO:0005739]; post-mRNA release spliceosomal complex [GO:0071014]	RNA binding [GO:0003723]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]
d1wi6a1_d5t9pc___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; RNA binding [GO:0003723]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleus [GO:0005634]; preribosome, large subunit precursor [GO:0030687]; rRNA binding [GO:0019843]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit biogenesis [GO:0042273]		maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit biogenesis [GO:0042273]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleus [GO:0005634]; preribosome, large subunit precursor [GO:0030687]	RNA binding [GO:0003723]	rRNA binding [GO:0019843]
d1wi8a1_d2mqma___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; polysome [GO:0005844]; RNA binding [GO:0003723]; RNA strand annealing activity [GO:0033592]; translation initiation factor activity [GO:0003743]; eukaryotic translation initiation factor 4F complex assembly [GO:0097010]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; ribonucleoprotein complex [GO:1990904]; ribonucleoprotein granule [GO:0035770]; mRNA 3'-UTR binding [GO:0003730]; mRNA CDS binding [GO:1990715]; pre-mRNA intronic binding [GO:0097157]; transcription regulatory region DNA binding [GO:0044212]; cellular response to amino acid starvation [GO:0034198]; circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to peptide [GO:1901652]	eukaryotic translation initiation factor 4F complex assembly [GO:0097010]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	cellular response to amino acid starvation [GO:0034198]; circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to peptide [GO:1901652]	cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; polysome [GO:0005844]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; ribonucleoprotein complex [GO:1990904]; ribonucleoprotein granule [GO:0035770]	RNA binding [GO:0003723]; RNA strand annealing activity [GO:0033592]; translation initiation factor activity [GO:0003743]	mRNA 3'-UTR binding [GO:0003730]; mRNA CDS binding [GO:1990715]; pre-mRNA intronic binding [GO:0097157]; transcription regulatory region DNA binding [GO:0044212]
d1wiaa1_d1he8a3__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; ubiquitin-dependent ERAD pathway [GO:0030433]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	ubiquitin-dependent ERAD pathway [GO:0030433]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]		GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1wiba1_d2vhmi2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosolic large ribosomal subunit [GO:0022625]; large ribosomal subunit [GO:0015934]; nucleolus [GO:0005730]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; large ribosomal subunit rRNA binding [GO:0070180]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		cytoplasm [GO:0005737]; cytosolic large ribosomal subunit [GO:0022625]; large ribosomal subunit [GO:0015934]; nucleolus [GO:0005730]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]		large ribosomal subunit rRNA binding [GO:0070180]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1wifa1_d1x5ra1__1	Metazoa	Metazoa	Chordata	Chordata		cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor signaling complex adaptor activity [GO:0030159]; artery smooth muscle contraction [GO:0014824]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; Notch signaling pathway [GO:0007219]; positive regulation of blood pressure [GO:0045777]; vesicle-mediated transport in synapse [GO:0099003]		artery smooth muscle contraction [GO:0014824]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; Notch signaling pathway [GO:0007219]; positive regulation of blood pressure [GO:0045777]; vesicle-mediated transport in synapse [GO:0099003]		cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]		receptor signaling complex adaptor activity [GO:0030159]
d1wifa1_d2k1za___1	Metazoa	Metazoa	Chordata	Chordata		adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; axonal growth cone [GO:0044295]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell cortex [GO:0005938]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; endomembrane system [GO:0012505]; internode region of axon [GO:0033269]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein phosphatase binding [GO:0019903]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; protein localization [GO:0008104]; protein targeting to membrane [GO:0006612]; regulation of cellular localization [GO:0060341]		bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; protein localization [GO:0008104]; protein targeting to membrane [GO:0006612]; regulation of cellular localization [GO:0060341]		adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; axonal growth cone [GO:0044295]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; endomembrane system [GO:0012505]; internode region of axon [GO:0033269]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]		identical protein binding [GO:0042802]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol binding [GO:0035091]; protein phosphatase binding [GO:0019903]
d1wika1_d2okad___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]; [2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]		[2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]		cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]		electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]	
d1wioa2_d4cadj1__1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]; CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]
d1wioa3_d3e3qe___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	adaptive immune response [GO:0002250]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	T cell receptor complex [GO:0042101]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1wioa4_d3pwve___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1wiob1_d1qlfb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1wiob2_d1f4yh2__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1wiob2_d1kipb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1wiob3_d1oqoa1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1wipa1_d3zdxl1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1wipa4_d1z7zi1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]
d1wipb2_d2rcje2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1wipb4_d1hnfa2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	anchored component of plasma membrane [GO:0046658]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; membrane raft polarization [GO:0001766]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of T cell differentiation [GO:0045580]; T cell activation [GO:0042110]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	apoptotic process [GO:0006915]; cell-cell adhesion [GO:0098609]; cell surface receptor signaling pathway [GO:0007166]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; membrane raft polarization [GO:0001766]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of T cell differentiation [GO:0045580]; T cell activation [GO:0042110]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	anchored component of plasma membrane [GO:0046658]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]
d1wipb4_d3h3bd2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]
d1wiqa1_d3kykl2__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d1wiqa4_d1g9mc2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1wiqa4_d1reib___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]
d1wiqb1_d3p9le___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1wiqb2_d3gsnl1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1wiza1_d2csfa1__1	Metazoa	Metazoa	Chordata	Chordata	histone deacetylase complex [GO:0000118]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cartilage development [GO:0051216]; cellular response to organic substance [GO:0071310]; chromatin remodeling [GO:0006338]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; embryonic pattern specification [GO:0009880]; embryonic skeletal system morphogenesis [GO:0048704]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron migration [GO:0001764]; osteoblast development [GO:0002076]; roof of mouth development [GO:0060021]	histone deacetylase complex [GO:0000118]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cartilage development [GO:0051216]; cellular response to organic substance [GO:0071310]; chromatin remodeling [GO:0006338]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; embryonic pattern specification [GO:0009880]; embryonic skeletal system morphogenesis [GO:0048704]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron migration [GO:0001764]; osteoblast development [GO:0002076]; roof of mouth development [GO:0060021]	cartilage development [GO:0051216]; cellular response to organic substance [GO:0071310]; chromatin remodeling [GO:0006338]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; embryonic pattern specification [GO:0009880]; embryonic skeletal system morphogenesis [GO:0048704]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron migration [GO:0001764]; osteoblast development [GO:0002076]; roof of mouth development [GO:0060021]	cartilage development [GO:0051216]; cellular response to organic substance [GO:0071310]; chromatin remodeling [GO:0006338]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; embryonic pattern specification [GO:0009880]; embryonic skeletal system morphogenesis [GO:0048704]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron migration [GO:0001764]; osteoblast development [GO:0002076]; roof of mouth development [GO:0060021]	histone deacetylase complex [GO:0000118]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	histone deacetylase complex [GO:0000118]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d1wj5a1_d1usta___1	Metazoa	Fungi	Chordata	Ascomycota	chromosome, telomeric region [GO:0000781]; CST complex [GO:1990879]; DNA replication factor A complex [GO:0005662]; fibrillar center [GO:0001650]; intermediate filament cytoskeleton [GO:0045111]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; telomeric DNA binding [GO:0042162]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nucleotide-excision repair [GO:0006289]; positive regulation of DNA replication [GO:0045740]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833]	chromatin [GO:0000785]; nuclear chromatin [GO:0000790]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; nucleosomal DNA binding [GO:0031492]; phosphate ion binding [GO:0042301]; supercoiled DNA binding [GO:0097100]; chromosome condensation [GO:0030261]; negative regulation of chromatin silencing [GO:0031936]; negative regulation of DNA recombination [GO:0045910]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; regulation of transcription, DNA-templated [GO:0006355]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nucleotide-excision repair [GO:0006289]; positive regulation of DNA replication [GO:0045740]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833]	chromosome condensation [GO:0030261]; negative regulation of chromatin silencing [GO:0031936]; negative regulation of DNA recombination [GO:0045910]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; regulation of transcription, DNA-templated [GO:0006355]	chromosome, telomeric region [GO:0000781]; CST complex [GO:1990879]; DNA replication factor A complex [GO:0005662]; fibrillar center [GO:0001650]; intermediate filament cytoskeleton [GO:0045111]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]	chromatin [GO:0000785]; nuclear chromatin [GO:0000790]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]	single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; telomeric DNA binding [GO:0042162]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; nucleosomal DNA binding [GO:0031492]; phosphate ion binding [GO:0042301]; supercoiled DNA binding [GO:0097100]
d1wj8b__d1ufbc___1				Deinococcus-Thermus		phosphorelay signal transduction system [GO:0000160]		phosphorelay signal transduction system [GO:0000160]				
d1wj8d__d1knyb1__1				Firmicutes		nucleotidyltransferase activity [GO:0016779]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]				nucleotidyltransferase activity [GO:0016779]
d1wjma1_d1y19b2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic spectrin-associated cytoskeleton [GO:0099189]; presynapse [GO:0098793]; spectrin [GO:0008091]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; phospholipid binding [GO:0005543]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of synapse [GO:0098918]; actin filament capping [GO:0051693]; adult behavior [GO:0030534]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; axon guidance [GO:0007411]; cerebellar Purkinje cell layer morphogenesis [GO:0021692]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]; multicellular organism growth [GO:0035264]; postsynapse organization [GO:0099173]; synapse assembly [GO:0007416]; vesicle-mediated transport [GO:0016192]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	actin filament capping [GO:0051693]; adult behavior [GO:0030534]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; axon guidance [GO:0007411]; cerebellar Purkinje cell layer morphogenesis [GO:0021692]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]; multicellular organism growth [GO:0035264]; postsynapse organization [GO:0099173]; synapse assembly [GO:0007416]; vesicle-mediated transport [GO:0016192]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic spectrin-associated cytoskeleton [GO:0099189]; presynapse [GO:0098793]; spectrin [GO:0008091]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; phospholipid binding [GO:0005543]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of synapse [GO:0098918]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]
d1wjra1_d2bivc1__1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone binding [GO:0042393]; transcription corepressor activity [GO:0003714]; negative regulation of gene expression [GO:0010629]; regulation of transcription, DNA-templated [GO:0006355]	nucleus [GO:0005634]; PcG protein complex [GO:0031519]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; anatomical structure morphogenesis [GO:0009653]	negative regulation of gene expression [GO:0010629]; regulation of transcription, DNA-templated [GO:0006355]	anatomical structure morphogenesis [GO:0009653]	aggresome [GO:0016235]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleus [GO:0005634]; PcG protein complex [GO:0031519]	histone binding [GO:0042393]; transcription corepressor activity [GO:0003714]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1wjra1_d2vytb2__1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone binding [GO:0042393]; transcription corepressor activity [GO:0003714]; negative regulation of gene expression [GO:0010629]; regulation of transcription, DNA-templated [GO:0006355]	nucleus [GO:0005634]; PcG protein complex [GO:0031519]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; anatomical structure morphogenesis [GO:0009653]	negative regulation of gene expression [GO:0010629]; regulation of transcription, DNA-templated [GO:0006355]	anatomical structure morphogenesis [GO:0009653]	aggresome [GO:0016235]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear body [GO:0016604]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleus [GO:0005634]; PcG protein complex [GO:0031519]	histone binding [GO:0042393]; transcription corepressor activity [GO:0003714]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1wk0a1_d3rzwb___1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; vesicle membrane [GO:0012506]; RNA binding [GO:0003723]; cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; vesicle membrane [GO:0012506]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	RNA binding [GO:0003723]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d1wk8b__d1jzsa2__1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; isoleucyl-tRNA aminoacylation [GO:0006428]	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; isoleucyl-tRNA aminoacylation [GO:0006428]	isoleucyl-tRNA aminoacylation [GO:0006428]	isoleucyl-tRNA aminoacylation [GO:0006428]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1wkga__d2g6wa___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	8-amino-7-oxononanoate synthase activity [GO:0008710]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	biotin biosynthetic process [GO:0009102]	cytoplasm [GO:0005737]		pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	8-amino-7-oxononanoate synthase activity [GO:0008710]; pyridoxal phosphate binding [GO:0030170]
d1wkga__d2z1za___1		Viridiplantae	Deinococcus-Thermus	Streptophyta	cytoplasm [GO:0005737]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d1wkgb__d3qboa___1			Deinococcus-Thermus		cytoplasm [GO:0005737]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]		arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]		cytoplasm [GO:0005737]		pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	
d1wkha__d4wxfc___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]
d1wkha__d5i90b___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	outer membrane-bounded periplasmic space [GO:0030288]; catalytic activity [GO:0003824]; pyoverdine biosynthetic process [GO:0002049]	arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	pyoverdine biosynthetic process [GO:0002049]	cytoplasm [GO:0005737]	outer membrane-bounded periplasmic space [GO:0030288]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	catalytic activity [GO:0003824]
d1wkjb__d5ioli1__1		Metazoa	Deinococcus-Thermus	Platyhelminthes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	nucleoside diphosphate kinase activity [GO:0004550]
d1wkka__d1vyae___1		Viridiplantae	Deinococcus-Thermus	Streptophyta	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]
d1wkob__d3n08a1__1	Viridiplantae		Streptophyta	Chlamydiae	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vacuole [GO:0005773]; vesicle [GO:0031982]; transcription coregulator activity [GO:0003712]; cell differentiation [GO:0030154]; flower development [GO:0009908]; meristem determinacy [GO:0010022]; negative regulation of cell aging [GO:0090344]; negative regulation of flower development [GO:0009910]; protein targeting to vacuole [GO:0006623]; response to sucrose [GO:0009744]; vegetative to reproductive phase transition of meristem [GO:0010228]		cell differentiation [GO:0030154]; flower development [GO:0009908]; meristem determinacy [GO:0010022]; negative regulation of cell aging [GO:0090344]; negative regulation of flower development [GO:0009910]; protein targeting to vacuole [GO:0006623]; response to sucrose [GO:0009744]; vegetative to reproductive phase transition of meristem [GO:0010228]		cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vacuole [GO:0005773]; vesicle [GO:0031982]		transcription coregulator activity [GO:0003712]	
d1wkpc__d1beha___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; phosphatidylethanolamine binding [GO:0008429]; cell differentiation [GO:0030154]; flower development [GO:0009908]; meristem determinacy [GO:0010022]; photoperiodism, flowering [GO:0048573]; positive regulation of flower development [GO:0009911]; regulation of flower development [GO:0009909]; regulation of stomatal movement [GO:0010119]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; phosphatidylethanolamine binding [GO:0008429]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; serine-type endopeptidase inhibitor activity [GO:0004867]; MAPK cascade [GO:0000165]; negative regulation of MAPK cascade [GO:0043409]	cell differentiation [GO:0030154]; flower development [GO:0009908]; meristem determinacy [GO:0010022]; photoperiodism, flowering [GO:0048573]; positive regulation of flower development [GO:0009911]; regulation of flower development [GO:0009909]; regulation of stomatal movement [GO:0010119]	MAPK cascade [GO:0000165]; negative regulation of MAPK cascade [GO:0043409]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	phosphatidylethanolamine binding [GO:0008429]	ATP binding [GO:0005524]; enzyme binding [GO:0019899]; phosphatidylethanolamine binding [GO:0008429]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; serine-type endopeptidase inhibitor activity [GO:0004867]
d1wkqa1_d2g84b1__1			Firmicutes	Proteobacteria	guanine deaminase activity [GO:0008892]; guanosine deaminase activity [GO:0047974]; zinc ion binding [GO:0008270]; guanine catabolic process [GO:0006147]; purine nucleoside catabolic process [GO:0006152]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]	guanine catabolic process [GO:0006147]; purine nucleoside catabolic process [GO:0006152]				guanine deaminase activity [GO:0008892]; guanosine deaminase activity [GO:0047974]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]
d1wkqa1_d2z3hd___1		Fungi	Firmicutes	Ascomycota	guanine deaminase activity [GO:0008892]; guanosine deaminase activity [GO:0047974]; zinc ion binding [GO:0008270]; guanine catabolic process [GO:0006147]; purine nucleoside catabolic process [GO:0006152]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	guanine catabolic process [GO:0006147]; purine nucleoside catabolic process [GO:0006152]	response to antibiotic [GO:0046677]			guanine deaminase activity [GO:0008892]; guanosine deaminase activity [GO:0047974]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d1wkua1_d1dxxa2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	cell [GO:0005623]; cell surface [GO:0009986]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]; actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein localization [GO:0034613]; cellular protein-containing complex assembly [GO:0034622]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein-containing complex assembly [GO:0034622]; cellular protein localization [GO:0034613]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]	cell [GO:0005623]; cell-substrate junction [GO:0030055]; cell surface [GO:0009986]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]	actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]
d1wkua1_d3hocb1__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d1wkua2_d1bkra___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	axolemma [GO:0030673]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; nucleolus [GO:0005730]; postsynaptic density [GO:0014069]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390]	focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390]	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]	axolemma [GO:0030673]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; nucleolus [GO:0005730]; postsynaptic density [GO:0014069]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]
d1wkua2_d3hopa2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d1wkva1_d1o58a1__1			Crenarchaeota	Thermotogae	cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]; cysteine biosynthetic process from serine [GO:0006535]	cysteine synthase activity [GO:0004124]; cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]			cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]	cysteine synthase activity [GO:0004124]
d1wkya2_d1v08a___1		Viridiplantae	Firmicutes	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]		chloroplast [GO:0009507]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]
d1wl4a2_d2bz3d1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; acetyl-CoA C-acyltransferase activity [GO:0003988]; cholesterol biosynthetic process [GO:0006695]; fatty acid beta-oxidation [GO:0006635]; lipid metabolic process [GO:0006629]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cholesterol biosynthetic process [GO:0006695]; fatty acid beta-oxidation [GO:0006635]; lipid metabolic process [GO:0006629]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]; acetyl-CoA C-acyltransferase activity [GO:0003988]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1wl7a1_d5aydf___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	arabinan catabolic process [GO:0031222]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	cytoplasm [GO:0005737]		arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]	transferase activity, transferring glycosyl groups [GO:0016757]
d1wlhb3_d1euta1__1				Actinobacteria	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]; actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]; actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	metabolic process [GO:0008152]	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]	extracellular region [GO:0005576]	actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1wlkc__d3awha___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	cofactor binding [GO:0048037]	cofactor binding [GO:0048037]
d1wlkd__d3zofa___1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	FMN binding [GO:0010181]	oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]		cofactor binding [GO:0048037]	FMN binding [GO:0010181]
d1wlla__d3u34a___1				Proteobacteria		cofactor binding [GO:0048037]						cofactor binding [GO:0048037]
d1wllb__d2aq6a___1				Actinobacteria		coenzyme F420 binding [GO:0070967]; FMN binding [GO:0010181]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; vitamin B6 metabolic process [GO:0042816]		vitamin B6 metabolic process [GO:0042816]				coenzyme F420 binding [GO:0070967]; FMN binding [GO:0010181]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]
d1wllb__d3k87b___1				Proteobacteria		FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [GO:0016646]; protein homodimerization activity [GO:0042803]; aromatic compound catabolic process [GO:0019439]; oxidation-reduction process [GO:0055114]		aromatic compound catabolic process [GO:0019439]; oxidation-reduction process [GO:0055114]				FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [GO:0016646]; protein homodimerization activity [GO:0042803]
d1wlma1_d2dfso1__1	Metazoa	Metazoa	Chordata	Chordata	microtubule [GO:0005874]; microtubule bundle [GO:0097427]; perinuclear region of cytoplasm [GO:0048471]; tubulin binding [GO:0015631]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; positive regulation of protein polymerization [GO:0032273]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; positive regulation of protein polymerization [GO:0032273]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	microtubule [GO:0005874]; microtubule bundle [GO:0097427]; perinuclear region of cytoplasm [GO:0048471]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]	tubulin binding [GO:0015631]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]
d1wlna1_d3poaa1__1	Metazoa		Chordata	Actinobacteria	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; pore complex [GO:0046930]; somatodendritic compartment [GO:0036477]; tight junction [GO:0070160]; actin filament binding [GO:0051015]; cell adhesion molecule binding [GO:0050839]; LIM domain binding [GO:0030274]; Ras GTPase binding [GO:0017016]; adherens junction maintenance [GO:0034334]; bicellular tight junction assembly [GO:0070830]; brain morphogenesis [GO:0048854]; cell-cell adhesion mediated by cadherin [GO:0044331]; cerebral cortex development [GO:0021987]; dendrite arborization [GO:0140059]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of protein localization to plasma membrane [GO:0061951]; homeostasis of number of cells [GO:0048872]; negative regulation of cell migration [GO:0030336]; neuroepithelial cell differentiation [GO:0060563]; pore complex assembly [GO:0046931]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of dendrite extension [GO:1903861]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; protein localization to cell junction [GO:1902414]; radial glial cell differentiation [GO:0060019]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165]; telencephalon development [GO:0021537]	cell wall [GO:0005618]; cytosol [GO:0005829]; mRNA binding [GO:0003729]	adherens junction maintenance [GO:0034334]; bicellular tight junction assembly [GO:0070830]; brain morphogenesis [GO:0048854]; cell-cell adhesion mediated by cadherin [GO:0044331]; cerebral cortex development [GO:0021987]; dendrite arborization [GO:0140059]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of protein localization to plasma membrane [GO:0061951]; homeostasis of number of cells [GO:0048872]; negative regulation of cell migration [GO:0030336]; neuroepithelial cell differentiation [GO:0060563]; pore complex assembly [GO:0046931]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of dendrite extension [GO:1903861]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; protein localization to cell junction [GO:1902414]; radial glial cell differentiation [GO:0060019]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165]; telencephalon development [GO:0021537]		adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; pore complex [GO:0046930]; somatodendritic compartment [GO:0036477]; tight junction [GO:0070160]	cell wall [GO:0005618]; cytosol [GO:0005829]	actin filament binding [GO:0051015]; cell adhesion molecule binding [GO:0050839]; LIM domain binding [GO:0030274]; Ras GTPase binding [GO:0017016]	mRNA binding [GO:0003729]
d1wlta1_d1rtva1__1			Crenarchaeota	Proteobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dTDP-rhamnose biosynthetic process [GO:0019305]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]			dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d1wlta1_d4j1xb2__1			Crenarchaeota	Actinobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	dTDP-rhamnose biosynthetic process [GO:0019305]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]			dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d1wltb__d1nywb___1			Crenarchaeota	Firmicutes	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-rhamnose biosynthetic process [GO:0019305]				dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d1wlva__d4qd8b___1			Deinococcus-Thermus	Proteobacteria	thiolester hydrolase activity [GO:0016790]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]				cytosol [GO:0005829]	thiolester hydrolase activity [GO:0016790]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]
d1wlvb__d4k4cb___1			Deinococcus-Thermus	Proteobacteria	thiolester hydrolase activity [GO:0016790]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; thiolester hydrolase activity [GO:0016790]; enterobactin biosynthetic process [GO:0009239]		enterobactin biosynthetic process [GO:0009239]		cytosol [GO:0005829]	thiolester hydrolase activity [GO:0016790]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; thiolester hydrolase activity [GO:0016790]
d1wlvc__d4zw0a___1			Deinococcus-Thermus	Proteobacteria	thiolester hydrolase activity [GO:0016790]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	thiolester hydrolase activity [GO:0016790]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d1wlzc__d4xjkc___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	nucleoplasm [GO:0005654]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium ion binding [GO:0005509]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1wlzd__d1djwb1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]		G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	nucleoplasm [GO:0005654]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]
d1wm1a__d1xrna___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]	aminopeptidase activity [GO:0004177]			cytoplasm [GO:0005737]		aminopeptidase activity [GO:0004177]	aminopeptidase activity [GO:0004177]
d1wm2a__d3h7sa___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1wm4a__d1jhwa1__1	Metazoa	Metazoa	Chordata	Chordata	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]; defense response to fungus [GO:0050832]; regulation of actin filament polymerization [GO:0030833]	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	defense response to fungus [GO:0050832]; regulation of actin filament polymerization [GO:0030833]	barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]
d1wm6c__d2h4ua1__1		Metazoa	Deinococcus-Thermus	Chordata	thiolester hydrolase activity [GO:0016790]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]; acyl-CoA hydrolase activity [GO:0047617]; acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]		acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]	thiolester hydrolase activity [GO:0016790]	acyl-CoA hydrolase activity [GO:0047617]
d1wm6e__d3az8u___1			Deinococcus-Thermus	Apicomplexa	thiolester hydrolase activity [GO:0016790]	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]			thiolester hydrolase activity [GO:0016790]	hydro-lyase activity [GO:0016836]
d1wm9a1_d2yzch1__1			Deinococcus-Thermus	Actinobacteria	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]			GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1wm9d__d5ll1h2__1		Metazoa	Deinococcus-Thermus	Chordata	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1wmaa1_d4uvga___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; 15-hydroxyprostaglandin dehydrogenase (NADP+) activity [GO:0047021]; carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; prostaglandin-E2 9-reductase activity [GO:0050221]; cyclooxygenase pathway [GO:0019371]; drug metabolic process [GO:0017144]; epithelial cell differentiation [GO:0030855]; oxidation-reduction process [GO:0055114]; vitamin K metabolic process [GO:0042373]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cyclooxygenase pathway [GO:0019371]; drug metabolic process [GO:0017144]; epithelial cell differentiation [GO:0030855]; oxidation-reduction process [GO:0055114]; vitamin K metabolic process [GO:0042373]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	15-hydroxyprostaglandin dehydrogenase (NADP+) activity [GO:0047021]; carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; prostaglandin-E2 9-reductase activity [GO:0050221]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d1wmbb__d1t2fb1__1		Metazoa	Proteobacteria	Chordata	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; identical protein binding [GO:0042802]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; pyruvate metabolic process [GO:0006090]		carbohydrate metabolic process [GO:0005975]; pyruvate metabolic process [GO:0006090]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	identical protein binding [GO:0042802]; L-lactate dehydrogenase activity [GO:0004459]
d1wmhb__d1c9fa___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell cortex [GO:0005938]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; GTP-dependent protein binding [GO:0030742]; protein kinase C binding [GO:0005080]; Rho GTPase binding [GO:0017048]; transcription factor binding [GO:0008134]; bicellular tight junction assembly [GO:0070830]; cell division [GO:0051301]; cell-cell junction maintenance [GO:0045217]; centrosome cycle [GO:0007098]; establishment or maintenance of cell polarity [GO:0007163]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of protein secretion [GO:0050714]; regulation of cellular localization [GO:0060341]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; deoxyribonuclease activity [GO:0004536]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclease activity [GO:0004518]; protein domain specific binding [GO:0019904]; apoptotic chromosome condensation [GO:0030263]; apoptotic DNA fragmentation [GO:0006309]; DNA catabolic process [GO:0006308]; protein homooligomerization [GO:0051260]	bicellular tight junction assembly [GO:0070830]; cell-cell junction maintenance [GO:0045217]; cell division [GO:0051301]; centrosome cycle [GO:0007098]; establishment or maintenance of cell polarity [GO:0007163]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of protein secretion [GO:0050714]; regulation of cellular localization [GO:0060341]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	apoptotic chromosome condensation [GO:0030263]; apoptotic DNA fragmentation [GO:0006309]; DNA catabolic process [GO:0006308]; protein homooligomerization [GO:0051260]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell cortex [GO:0005938]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ruffle [GO:0001726]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	GTP-dependent protein binding [GO:0030742]; protein kinase C binding [GO:0005080]; Rho GTPase binding [GO:0017048]; transcription factor binding [GO:0008134]	deoxyribonuclease activity [GO:0004536]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclease activity [GO:0004518]; protein domain specific binding [GO:0019904]
d1wmia1_d4lsyb___1			Euryarchaeota	Proteobacteria		endoribonuclease activity [GO:0004521]; mRNA catabolic process [GO:0006402]; translational termination [GO:0006415]		mRNA catabolic process [GO:0006402]; translational termination [GO:0006415]				endoribonuclease activity [GO:0004521]
d1wmrb2_d2iq7e___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; isopullulanase activity [GO:0051675]; metabolic process [GO:0008152]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	isopullulanase activity [GO:0051675]	polygalacturonase activity [GO:0004650]
d1wmub__d2uuni___1	Metazoa		Chordata		hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1wmxa__d3muz11__1			Firmicutes	Proteobacteria	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1wmxb__d4bj0a1__1			Firmicutes	Bacteroidetes	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]			cellulase activity [GO:0008810]; metal ion binding [GO:0046872]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; metal ion binding [GO:0046872]
d1wmya__d4gjxd___1	Metazoa	Metazoa	Echinodermata	Chordata	metal ion binding [GO:0046872]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d1wn0a1_d2a0ba___1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; cytokinin-activated signaling pathway [GO:0009736]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]; positive regulation of cytokinin-activated signaling pathway [GO:0080038]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; phosphorelay sensor kinase activity [GO:0000155]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction by protein phosphorylation [GO:0023014]	cytokinin-activated signaling pathway [GO:0009736]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]; positive regulation of cytokinin-activated signaling pathway [GO:0080038]	protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; phosphorelay sensor kinase activity [GO:0000155]
d1wn2a__d2zv3b___1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	aminoacyl-tRNA hydrolase activity [GO:0004045]	aminoacyl-tRNA hydrolase activity [GO:0004045]
d1wn3h__d4fq9d___1			Deinococcus-Thermus	Proteobacteria	thiolester hydrolase activity [GO:0016790]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]		unsaturated fatty acid biosynthetic process [GO:0006636]		cytoplasm [GO:0005737]	thiolester hydrolase activity [GO:0016790]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]
d1wn5b__d4lcob1__1	Fungi		Ascomycota	Proteobacteria	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]	response to antibiotic [GO:0046677]				blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]
d1wn5c__d1mq0a___1	Fungi	Metazoa	Ascomycota	Chordata	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytidine deaminase activity [GO:0004126]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; cell surface receptor signaling pathway [GO:0007166]; cytidine deamination [GO:0009972]; cytosine metabolic process [GO:0019858]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; neutrophil degranulation [GO:0043312]; protein homotetramerization [GO:0051289]; pyrimidine nucleoside salvage [GO:0043097]; pyrimidine-containing compound salvage [GO:0008655]	response to antibiotic [GO:0046677]	cell surface receptor signaling pathway [GO:0007166]; cytidine deamination [GO:0009972]; cytosine metabolic process [GO:0019858]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; neutrophil degranulation [GO:0043312]; protein homotetramerization [GO:0051289]; pyrimidine-containing compound salvage [GO:0008655]; pyrimidine nucleoside salvage [GO:0043097]		cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]
d1wn6a__d1pl0a2__1	Fungi	Metazoa	Ascomycota	Chordata	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	response to antibiotic [GO:0046677]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1wn6b__d1pkxd2__1	Fungi	Metazoa	Ascomycota	Chordata	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]	response to antibiotic [GO:0046677]	'de novo' IMP biosynthetic process [GO:0006189]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1wnbc__d4nmje___1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; 1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; putrescine catabolic process [GO:0009447]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	putrescine catabolic process [GO:0009447]		cytosol [GO:0005829]		1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d1wnda__d1o02d___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; 1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; putrescine catabolic process [GO:0009447]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	putrescine catabolic process [GO:0009447]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d1wndb__d3zqab___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; putrescine catabolic process [GO:0009447]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	putrescine catabolic process [GO:0009447]	glycine betaine biosynthetic process from choline [GO:0019285]	cytosol [GO:0005829]		1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]
d1wnha1_d2w9pf___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; heparin binding [GO:0008201]; metalloendopeptidase inhibitor activity [GO:0008191]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]	cysteine-type endopeptidase inhibitor activity [GO:0004869]	detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]		cytoplasm [GO:0005737]; extracellular space [GO:0005615]		heparin binding [GO:0008201]; metalloendopeptidase inhibitor activity [GO:0008191]	cysteine-type endopeptidase inhibitor activity [GO:0004869]
d1wnha2_d1iv7a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; heparin binding [GO:0008201]; metalloendopeptidase inhibitor activity [GO:0008191]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]		detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; inflammatory response [GO:0006954]		cytoplasm [GO:0005737]; extracellular space [GO:0005615]		heparin binding [GO:0008201]; metalloendopeptidase inhibitor activity [GO:0008191]	
d1wnlb2_d4ycwe2__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]; activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	cellular protein modification process [GO:0006464]	activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]		aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]	amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]
d1wnqb__d1a1qc___1						extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1wntb__d1yxma1__1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; cytoplasmic microtubule [GO:0005881]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NAD+) activity [GO:0044105]; L-xylulose reductase (NADP+) activity [GO:0050038]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; signaling receptor binding [GO:0005102]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid alpha-oxidation [GO:0001561]; fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114]; phytol metabolic process [GO:0033306]; protein targeting to peroxisome [GO:0006625]	D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	fatty acid alpha-oxidation [GO:0001561]; fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114]; phytol metabolic process [GO:0033306]; protein targeting to peroxisome [GO:0006625]	brush border [GO:0005903]; cytoplasmic microtubule [GO:0005881]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NAD+) activity [GO:0044105]; L-xylulose reductase (NADP+) activity [GO:0050038]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]	signaling receptor binding [GO:0005102]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]
d1wntd__d4bgva1__1	Metazoa		Chordata	Euryarchaeota	brush border [GO:0005903]; cytoplasmic microtubule [GO:0005881]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NAD+) activity [GO:0044105]; L-xylulose reductase (NADP+) activity [GO:0050038]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; glucuronate catabolic process to xylulose 5-phosphate [GO:0019640]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	brush border [GO:0005903]; cytoplasmic microtubule [GO:0005881]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; L-xylulose reductase (NAD+) activity [GO:0044105]; L-xylulose reductase (NADP+) activity [GO:0050038]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]	L-malate dehydrogenase activity [GO:0030060]
d1wnvb__d1twnb___1		Metazoa	Actinobacteria	Chordata	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	heme oxidation [GO:0006788]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]		caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1wnvc__d1vgia___1		Metazoa	Actinobacteria	Chordata	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	heme oxidation [GO:0006788]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]		caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1wnvc__d5uc8b___1		Metazoa	Actinobacteria	Chordata	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	heme oxidation [GO:0006788]	cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d1wnxa__d1irmc___1		Metazoa	Actinobacteria	Chordata	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	heme oxidation [GO:0006788]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]		caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1wnxb__d5kzla___1			Actinobacteria	Spirochaetes	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; response to oxidative stress [GO:0006979]	heme oxidation [GO:0006788]	heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; response to oxidative stress [GO:0006979]			heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d1wnya__d1ffya2__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; isoleucyl-tRNA aminoacylation [GO:0006428]	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; isoleucyl-tRNA aminoacylation [GO:0006428]	isoleucyl-tRNA aminoacylation [GO:0006428]	isoleucyl-tRNA aminoacylation [GO:0006428]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; isoleucine-tRNA ligase activity [GO:0004822]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d1wo2a1_d1wpca1__1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]; starch catabolic process [GO:0005983]	carbohydrate catabolic process [GO:0016052]	starch catabolic process [GO:0005983]	extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]
d1wo2a2_d1y65a1__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	cytoplasm [GO:0005737]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; peptidoglycan-based cell wall biogenesis [GO:0009273]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan-based cell wall biogenesis [GO:0009273]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	extracellular space [GO:0005615]	cytoplasm [GO:0005737]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]
d1wo8a1_d1c30c2__1			Deinococcus-Thermus	Proteobacteria	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]		carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d1wo8c__d1s8ae___1			Deinococcus-Thermus	Proteobacteria	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]		cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	methylglyoxal synthase activity [GO:0008929]
d1wo8f__d1eghb___1			Deinococcus-Thermus	Proteobacteria	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]		cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	methylglyoxal synthase activity [GO:0008929]
d1wobb__d3tima___1			Apicomplexa		identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]; glycosome [GO:0020015]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1woda__d4elpc___1			Proteobacteria	Deinococcus-Thermus	outer membrane-bounded periplasmic space [GO:0030288]; ATPase-coupled molybdate transmembrane transporter activity [GO:0015412]; molybdate ion binding [GO:0030973]; molybdenum ion binding [GO:0030151]; tungstate binding [GO:1901359]; molybdate ion transport [GO:0015689]; response to chromate [GO:0046687]	metal ion binding [GO:0046872]	molybdate ion transport [GO:0015689]; response to chromate [GO:0046687]		outer membrane-bounded periplasmic space [GO:0030288]		ATPase-coupled molybdate transmembrane transporter activity [GO:0015412]; molybdate ion binding [GO:0030973]; molybdenum ion binding [GO:0030151]; tungstate binding [GO:1901359]	metal ion binding [GO:0046872]
d1woga1_d4qa1b1__1		Metazoa	Deinococcus-Thermus	Chordata	agmatinase activity [GO:0008783]; metal ion binding [GO:0046872]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]		cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	agmatinase activity [GO:0008783]; metal ion binding [GO:0046872]	histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]
d1woge1_d3rlab___1		Metazoa	Deinococcus-Thermus	Chordata	agmatinase activity [GO:0008783]; metal ion binding [GO:0046872]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	agmatinase activity [GO:0008783]; metal ion binding [GO:0046872]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1wohb1_d5eeia___1		Metazoa	Deinococcus-Thermus	Chordata	agmatinase activity [GO:0008783]; metal ion binding [GO:0046872]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]			agmatinase activity [GO:0008783]; metal ion binding [GO:0046872]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]
d1wohf1_d4cbyd1__1		Metazoa	Deinococcus-Thermus	Chordata	agmatinase activity [GO:0008783]; metal ion binding [GO:0046872]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	A band [GO:0031672]; actomyosin [GO:0042641]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; neuromuscular junction [GO:0031594]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; Z disc [GO:0030018]; activating transcription factor binding [GO:0033613]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; potassium ion binding [GO:0030955]; promoter-specific chromatin binding [GO:1990841]; protein deacetylase activity [GO:0033558]; protein kinase binding [GO:0019901]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; SUMO transferase activity [GO:0019789]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to mechanical stimulus [GO:0071260]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of glycolytic process [GO:0045820]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; osteoblast development [GO:0002076]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of male mating behavior [GO:1902437]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deacetylation [GO:0006476]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein binding [GO:0043393]; regulation of skeletal muscle fiber development [GO:0048742]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to drug [GO:0042493]; response to interleukin-1 [GO:0070555]; skeletal system development [GO:0001501]	putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to mechanical stimulus [GO:0071260]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of glycolytic process [GO:0045820]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; osteoblast development [GO:0002076]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of male mating behavior [GO:1902437]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein binding [GO:0043393]; regulation of skeletal muscle fiber development [GO:0048742]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to drug [GO:0042493]; response to interleukin-1 [GO:0070555]; skeletal system development [GO:0001501]		A band [GO:0031672]; actomyosin [GO:0042641]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; neuromuscular junction [GO:0031594]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; Z disc [GO:0030018]	agmatinase activity [GO:0008783]; metal ion binding [GO:0046872]	activating transcription factor binding [GO:0033613]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; potassium ion binding [GO:0030955]; promoter-specific chromatin binding [GO:1990841]; protein deacetylase activity [GO:0033558]; protein kinase binding [GO:0019901]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; SUMO transferase activity [GO:0019789]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1woma1_d3c6xa___1		Viridiplantae	Firmicutes	Streptophyta		aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]						aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]
d1woqa1_d1x9jf2__1			Actinobacteria	Thermotogae	kinase activity [GO:0016301]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]				cytoplasm [GO:0005737]	kinase activity [GO:0016301]	ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]
d1woqb1_d3c7nb2__1		Metazoa	Actinobacteria	Chordata	kinase activity [GO:0016301]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]		axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]		autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	kinase activity [GO:0016301]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d1wora1_d1pj5a1__1			Thermotogae	Actinobacteria	cytosol [GO:0005829]; aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]; glycine decarboxylation via glycine cleavage system [GO:0019464]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	glycine decarboxylation via glycine cleavage system [GO:0019464]		cytosol [GO:0005829]		aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]
d1wora1_d3a8jc2__1			Thermotogae	Proteobacteria	cytosol [GO:0005829]; aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]; glycine decarboxylation via glycine cleavage system [GO:0019464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]; lipoic acid binding [GO:0031405]; glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]	aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]	lipoic acid binding [GO:0031405]
d1woua__d2h72b___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxidase activity [GO:0004601]; protein-disulfide reductase activity [GO:0047134]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	peroxidase activity [GO:0004601]; protein-disulfide reductase activity [GO:0047134]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1wp4b2_d3ai3e___1			Deinococcus-Thermus	Proteobacteria	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]					NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1wp4c2_d1dlja2__1			Deinococcus-Thermus	Firmicutes	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	NAD binding [GO:0051287]; UDP-glucose 6-dehydrogenase activity [GO:0003979]; polysaccharide biosynthetic process [GO:0000271]; UDP-glucuronate biosynthetic process [GO:0006065]		polysaccharide biosynthetic process [GO:0000271]; UDP-glucuronate biosynthetic process [GO:0006065]			NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	NAD binding [GO:0051287]; UDP-glucose 6-dehydrogenase activity [GO:0003979]
d1wp6a1_d1ud5a1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]; starch catabolic process [GO:0005983]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	starch catabolic process [GO:0005983]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1wp6a2_d1gqka1__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]; starch catabolic process [GO:0005983]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	starch catabolic process [GO:0005983]	glucuronoxylan catabolic process [GO:2000886]	extracellular region [GO:0005576]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]	alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]
d1wp6a2_d3lxbb1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]; starch catabolic process [GO:0005983]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	starch catabolic process [GO:0005983]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d1wp9a1_d1tf2a4__1			Euryarchaeota	Firmicutes	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; DNA repair [GO:0006281]	cell envelope Sec protein transport complex [GO:0031522]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; ATPase-coupled protein transmembrane transporter activity [GO:0015462]; metal ion binding [GO:0046872]; intracellular protein transmembrane transport [GO:0065002]; protein import [GO:0017038]; protein targeting [GO:0006605]; protein transport by the Sec complex [GO:0043952]	DNA repair [GO:0006281]	intracellular protein transmembrane transport [GO:0065002]; protein import [GO:0017038]; protein targeting [GO:0006605]; protein transport by the Sec complex [GO:0043952]		cell envelope Sec protein transport complex [GO:0031522]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]	ATPase-coupled protein transmembrane transporter activity [GO:0015462]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d1wpld__d2a0sa1__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	metal ion binding [GO:0046872]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]	metal ion binding [GO:0046872]
d1wplg__d1wuqb___1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1wplg__d3plja1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]	urate oxidase activity [GO:0004846]
d1wplh__d1n3sa___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1wpli__d1n3rc___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1wplj__d3pkga1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]	urate oxidase activity [GO:0004846]
d1wpma__d1ir6a___1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; exopolyphosphatase activity [GO:0004309]; inorganic diphosphatase activity [GO:0004427]; manganese ion binding [GO:0030145]; polyphosphate catabolic process [GO:0006798]	DNA binding [GO:0003677]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]	polyphosphate catabolic process [GO:0006798]		cytoplasm [GO:0005737]		exopolyphosphatase activity [GO:0004309]; inorganic diphosphatase activity [GO:0004427]; manganese ion binding [GO:0030145]	DNA binding [GO:0003677]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]
d1wpqa1_d5itvc1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycerol-3-phosphate dehydrogenase (quinone) activity [GO:0004368]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophosphate shuttle [GO:0006127]; NADH oxidation [GO:0006116]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of glycolytic process [GO:0045821]	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]	cellular response to cAMP [GO:0071320]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophosphate shuttle [GO:0006127]; NADH oxidation [GO:0006116]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of glycolytic process [GO:0045821]	antibiotic biosynthetic process [GO:0017000]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]		glycerol-3-phosphate dehydrogenase (quinone) activity [GO:0004368]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]	oxidoreductase activity [GO:0016491]
d1wpqb2_d2jkvd2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycerol-3-phosphate dehydrogenase (quinone) activity [GO:0004368]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophosphate shuttle [GO:0006127]; NADH oxidation [GO:0006116]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of glycolytic process [GO:0045821]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate catabolic process [GO:0046177]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	cellular response to cAMP [GO:0071320]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophosphate shuttle [GO:0006127]; NADH oxidation [GO:0006116]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of glycolytic process [GO:0045821]	D-gluconate catabolic process [GO:0046177]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	glycerol-3-phosphate dehydrogenase (quinone) activity [GO:0004368]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]
d1wq1r__d1tq6a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	endoplasmic reticulum membrane [GO:0005789]; Golgi cisterna membrane [GO:0032580]; nuclear membrane [GO:0031965]; symbiont-containing vacuole membrane [GO:0020005]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	endoplasmic reticulum membrane [GO:0005789]; Golgi cisterna membrane [GO:0032580]; nuclear membrane [GO:0031965]; symbiont-containing vacuole membrane [GO:0020005]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1wq3a__d1yunb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]; tRNA aminoacylation [GO:0043039]; tyrosyl-tRNA aminoacylation [GO:0006437]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	tRNA aminoacylation [GO:0043039]; tyrosyl-tRNA aminoacylation [GO:0006437]	NAD biosynthetic process [GO:0009435]	cytosol [GO:0005829]; membrane [GO:0016020]		ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]
d1wqfa1_d4kb4a___1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]	cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]	cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]	ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]
d1wqga__d1wiha1__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]	mitochondrion [GO:0005739]; ribosomal large subunit binding [GO:0043023]; ribosome disassembly [GO:0032790]; translation [GO:0006412]	cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]	ribosome disassembly [GO:0032790]; translation [GO:0006412]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	mitochondrion [GO:0005739]	ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]	ribosomal large subunit binding [GO:0043023]
d1wqga__d4kawx___1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]	cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]	cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]	ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]
d1wqha__d3r8ny1__1			Actinobacteria		cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]		cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]	
d1wqla2_d4psba___1		Viridiplantae	Proteobacteria	Streptophyta	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]	abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]	cellular aromatic compound metabolic process [GO:0006725]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]			dioxygenase activity [GO:0051213]	abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d1wqoa__d150ld___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1wqqa__d1c6ca___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1wqqa__d4etaa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1wqua1_d1lkla___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule cytoskeleton [GO:0015630]; ATP binding [GO:0005524]; immunoglobulin receptor binding [GO:0034987]; microtubule binding [GO:0008017]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol binding [GO:0035091]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vitamin D [GO:0071305]; centrosome cycle [GO:0007098]; chemotaxis [GO:0006935]; microtubule bundle formation [GO:0001578]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of neuron projection development [GO:0010976]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell motility [GO:2000145]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of mast cell degranulation [GO:0043304]; regulation of vesicle-mediated transport [GO:0060627]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vitamin D [GO:0071305]; centrosome cycle [GO:0007098]; chemotaxis [GO:0006935]; microtubule bundle formation [GO:0001578]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of neuron projection development [GO:0010976]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell motility [GO:2000145]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of mast cell degranulation [GO:0043304]; regulation of vesicle-mediated transport [GO:0060627]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; hemopoiesis [GO:0030097]; leukocyte migration [GO:0050900]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule cytoskeleton [GO:0015630]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; immunoglobulin receptor binding [GO:0034987]; microtubule binding [GO:0008017]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol binding [GO:0035091]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]
d1wr1a__d1lfda___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP-dependent protein binding [GO:0043008]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; ascospore formation [GO:0030437]; modification-dependent protein catabolic process [GO:0019941]; protein deubiquitination [GO:0016579]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	ascospore formation [GO:0030437]; modification-dependent protein catabolic process [GO:0019941]; protein deubiquitination [GO:0016579]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	ATP-dependent protein binding [GO:0043008]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1wr8b__d2d2va___1			Euryarchaeota	Cyanobacteria	magnesium ion binding [GO:0000287]; phosphoglycolate phosphatase activity [GO:0008967]; carbohydrate metabolic process [GO:0005975]	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]; sucrose biosynthetic process [GO:0005986]	carbohydrate metabolic process [GO:0005975]	sucrose biosynthetic process [GO:0005986]			magnesium ion binding [GO:0000287]; phosphoglycolate phosphatase activity [GO:0008967]	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]
d1wr8b__d5alxa1__1		Metazoa	Euryarchaeota	Chordata	magnesium ion binding [GO:0000287]; phosphoglycolate phosphatase activity [GO:0008967]; carbohydrate metabolic process [GO:0005975]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	carbohydrate metabolic process [GO:0005975]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	magnesium ion binding [GO:0000287]; phosphoglycolate phosphatase activity [GO:0008967]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d1wraa1_d4dila1__1			Firmicutes	Thermotogae	metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1wrab__d3sfpa___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d1wrda1_d3zyka2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]; 1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]; axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]
d1wrdb__d3vtwb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d1wrle__d1ih0a___1	Metazoa	Metazoa	Chordata	Chordata	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]
d1wrra1_d1vaxd2__1	Fungi		Ascomycota		peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	
d1wrra1_d3qn9a___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	queuosine biosynthetic process [GO:0008616]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d1wrsr__d2xdib___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]
d1wrya1_d3dexa___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]				cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]		SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	
d1ws2a1_d4r8xa1__1	Fungi		Ascomycota	Firmicutes	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	
d1ws2b1_d2yzbg2__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1ws2b2_d2nm2c___1	Fungi		Ascomycota	Firmicutes	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]
d1ws2c1_d3pk3a2__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1ws2c2_d1gtpt___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1ws3c1_d1rrwa___1	Fungi		Ascomycota	Firmicutes	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]
d1ws3c1_d1xxja2__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1ws3c2_d3pksa1__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1ws7b__d1e5yc___1	Viridiplantae		Streptophyta	Proteobacteria	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1ws7d__d4hz1a___1	Viridiplantae		Streptophyta	Proteobacteria	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1ws8a__d1j9tc1__1	Viridiplantae		Streptophyta	Proteobacteria	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1wsda__d4ryde1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	extracellular region [GO:0005576]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d1wsga1_d4i7fa2__1			Proteobacteria		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1wsjb__d1dloa1__1			Proteobacteria		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1wspa1_d5tr4d___1	Metazoa	Fungi	Chordata	Ascomycota	beta-catenin destruction complex [GO:0030877]; cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein homooligomerization [GO:0051260]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ubiquitin activating enzyme activity [GO:0004839]; cellular response to DNA damage stimulus [GO:0006974]; protein modification by small protein conjugation [GO:0032446]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein homooligomerization [GO:0051260]; Wnt signaling pathway [GO:0016055]	cellular response to DNA damage stimulus [GO:0006974]; protein modification by small protein conjugation [GO:0032446]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	beta-catenin destruction complex [GO:0030877]; cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]	ATP binding [GO:0005524]; ubiquitin activating enzyme activity [GO:0004839]
d1wspb__d5emzf___1	Metazoa	Metazoa	Chordata	Chordata	beta-catenin destruction complex [GO:0030877]; cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein homooligomerization [GO:0051260]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein homooligomerization [GO:0051260]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	beta-catenin destruction complex [GO:0030877]; cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1wssh__d1hfda___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1wt5a__d1om3m1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1wt5c__d4nqef___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1wt9a1_d3alub___1	Metazoa	Metazoa	Chordata	Echinodermata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]
d1wt9b__d2q17c___1	Metazoa		Chordata	Actinobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	endoplasmic reticulum [GO:0005783]; calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]; post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]		post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]
d1wtca__d4d9ec___1	Fungi		Ascomycota	Proteobacteria	ATP binding [GO:0005524]; D-serine ammonia-lyase activity [GO:0008721]; L-serine ammonia-lyase activity [GO:0003941]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; serine racemase activity [GO:0030378]; threonine racemase activity [GO:0018114]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]	D-cysteine desulfhydrase activity [GO:0019148]; D-amino acid metabolic process [GO:0046416]	D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]	D-amino acid metabolic process [GO:0046416]			ATP binding [GO:0005524]; D-serine ammonia-lyase activity [GO:0008721]; L-serine ammonia-lyase activity [GO:0003941]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; serine racemase activity [GO:0030378]; threonine racemase activity [GO:0018114]	D-cysteine desulfhydrase activity [GO:0019148]
d1wtla__d5m94b___1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; metal ion transmembrane transporter activity [GO:0046873]; symporter activity [GO:0015293]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]	metal ion binding [GO:0046872]; metal ion transmembrane transporter activity [GO:0046873]; symporter activity [GO:0015293]
d1wtna__d1l97b___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1wtpa__d1bbxd___1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]	DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]
d1wtqa__d1wvlb___1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]	DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]
d1wtua__d5lvtb___1				Firmicutes	DNA binding [GO:0003677]	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]		chromosome condensation [GO:0030261]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1wtub__d2ht0a___1				Proteobacteria	DNA binding [GO:0003677]	chromosome [GO:0005694]; DNA binding [GO:0003677]; DNA recombination [GO:0006310]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]		DNA recombination [GO:0006310]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]		chromosome [GO:0005694]	DNA binding [GO:0003677]	DNA binding [GO:0003677]
d1wtwa__d4cj2c1__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	DNA binding [GO:0003677]; endoribonuclease activity [GO:0004521]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1wu1a__d1o2ua___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1wuaa2_d1okjb1__1	Metazoa		Chordata	Proteobacteria	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cytosol [GO:0005829]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]
d1wufa2_d2oneb2__1		Fungi	Firmicutes	Ascomycota	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	menaquinone biosynthetic process [GO:0009234]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1wufb2_d1ebga2__1		Fungi	Firmicutes	Ascomycota	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	menaquinone biosynthetic process [GO:0009234]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1wupa__d2whga___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1wupb__d5b15a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1wuqa__d1gtpj___1			Deinococcus-Thermus	Proteobacteria	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1wuqc__d1nbuh___1			Deinococcus-Thermus	Actinobacteria	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]			GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]
d1wuqd__d1gtpd___1			Deinococcus-Thermus	Proteobacteria	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1wuqd__d5ll1d1__1		Metazoa	Deinococcus-Thermus	Chordata	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1wuqe__d4op9a1__1		Fungi	Deinococcus-Thermus	Ascomycota	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	urate oxidase activity [GO:0004846]
d1wurd__d4du6a___1			Deinococcus-Thermus	Proteobacteria	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1wurd__d4ntkc___1			Deinococcus-Thermus	Proteobacteria	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	queuosine biosynthetic process [GO:0008616]			GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d1wuva__d1loa.3__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]	mannose binding [GO:0005537]	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]				mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]	mannose binding [GO:0005537]
d1wuvd__d1qotc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]				mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1wuvd__d3wluc___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]
d1wvea2_d5fxda1__1			Proteobacteria	Actinobacteria	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]					FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d1wvec__d1n15a1__1			Proteobacteria	Proteobacteria	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]				periplasmic space [GO:0042597]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1wved__d1n50b1__1			Proteobacteria	Proteobacteria	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]				periplasmic space [GO:0042597]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d1wvfa2_d3b9jb2__1		Metazoa	Proteobacteria	Chordata	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1wvid__d1o08a___1			Firmicutes	Firmicutes		cytoplasm [GO:0005737]; beta-phosphoglucomutase activity [GO:0008801]; hydrolase activity [GO:0016787]; magnesium ion binding [GO:0000287]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		cytoplasm [GO:0005737]		beta-phosphoglucomutase activity [GO:0008801]; hydrolase activity [GO:0016787]; magnesium ion binding [GO:0000287]
d1wvma__d1y1ke2__1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1wvva__d2h9ja___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1ww4a__d3wv6b1__1	Fungi	Metazoa	Basidiomycota	Chordata	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]
d1ww4b__d4yw1a1__1	Fungi		Basidiomycota	Firmicutes	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	carbohydrate metabolic process [GO:0005975]			deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1ww4c__d1s0ca1__1	Fungi		Basidiomycota	Firmicutes	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1ww4c__d5kxcc___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	carbohydrate binding [GO:0030246]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]				deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]
d1ww5a__d1ulfa___1	Fungi	Fungi	Basidiomycota	Basidiomycota	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]
d1ww5b__d1dyka1__1	Fungi	Metazoa	Basidiomycota	Chordata	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]		basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	signaling receptor binding [GO:0005102]
d1ww6a__d2eigd___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]				deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1ww6a__d2gnta___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]				deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1ww6c__d2arxa___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]				deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1ww7a__d5f5qa___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	calcium ion binding [GO:0005509]; glucose binding [GO:0005536]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]; vasodilation [GO:0042311]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	vasodilation [GO:0042311]			deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	calcium ion binding [GO:0005509]; glucose binding [GO:0005536]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]
d1ww7b__d2arxb___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]				deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1ww7c__d2vuaa1__1	Fungi		Basidiomycota	Firmicutes	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	negative regulation of neurotransmitter secretion [GO:0046929]		cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1ww7c__d5joxb2__1	Fungi		Basidiomycota	Bacteroidetes	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	periplasmic space [GO:0042597]; alpha-L-arabinofuranosidase activity [GO:0046556]; symbiotic process benefiting host [GO:0085030]; xyloglucan catabolic process [GO:2000899]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	symbiotic process benefiting host [GO:0085030]; xyloglucan catabolic process [GO:2000899]		periplasmic space [GO:0042597]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	alpha-L-arabinofuranosidase activity [GO:0046556]
d1ww7d__d1jxnc___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]				deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1ww9a1_d1ndoa1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	dioxygenase activity [GO:0051213]
d1wway__d1oazh___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome membrane [GO:0055038]; ATP binding [GO:0005524]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; nerve growth factor binding [GO:0048406]; nerve growth factor receptor activity [GO:0010465]; neurotrophin binding [GO:0043121]; neurotrophin p75 receptor binding [GO:0005166]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of MAPKK activity [GO:0000186]; aging [GO:0007568]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; B cell differentiation [GO:0030183]; behavioral response to formalin induced pain [GO:0061368]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to nicotine [GO:0071316]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; learning or memory [GO:0007611]; mechanoreceptor differentiation [GO:0042490]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; neurotrophin TRK receptor signaling pathway [GO:0048011]; olfactory nerve development [GO:0021553]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; programmed cell death involved in cell development [GO:0010623]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to hydrostatic pressure [GO:0051599]; response to nutrient levels [GO:0031667]; response to radiation [GO:0009314]; Sertoli cell development [GO:0060009]; sympathetic nervous system development [GO:0048485]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	activation of MAPKK activity [GO:0000186]; aging [GO:0007568]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; B cell differentiation [GO:0030183]; behavioral response to formalin induced pain [GO:0061368]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to nicotine [GO:0071316]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; learning or memory [GO:0007611]; mechanoreceptor differentiation [GO:0042490]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; neurotrophin TRK receptor signaling pathway [GO:0048011]; olfactory nerve development [GO:0021553]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; programmed cell death involved in cell development [GO:0010623]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to hydrostatic pressure [GO:0051599]; response to nutrient levels [GO:0031667]; response to radiation [GO:0009314]; Sertoli cell development [GO:0060009]; sympathetic nervous system development [GO:0048485]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome membrane [GO:0055038]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; nerve growth factor binding [GO:0048406]; nerve growth factor receptor activity [GO:0010465]; neurotrophin binding [GO:0043121]; neurotrophin p75 receptor binding [GO:0005166]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1wwhc__d3ud4p___1	Metazoa	Metazoa	Chordata	Chordata	nuclear lamina [GO:0005652]; nuclear membrane [GO:0031965]; nuclear pore central transport channel [GO:0044613]; nuclear pore nuclear basket [GO:0044615]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; single-stranded DNA binding [GO:0003697]; structural constituent of nuclear pore [GO:0017056]; cellular response to leukemia inhibitory factor [GO:1990830]; mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore organization [GO:0006999]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cellular response to leukemia inhibitory factor [GO:1990830]; mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore organization [GO:0006999]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	nuclear lamina [GO:0005652]; nuclear membrane [GO:0031965]; nuclear pore central transport channel [GO:0044613]; nuclear pore nuclear basket [GO:0044615]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; single-stranded DNA binding [GO:0003697]; structural constituent of nuclear pore [GO:0017056]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]
d1wwjc__d1fohd3__1		Fungi	Cyanobacteria	Basidiomycota	identical protein binding [GO:0042802]; circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]; phenol-containing compound catabolic process [GO:0019336]	circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]	phenol-containing compound catabolic process [GO:0019336]			identical protein binding [GO:0042802]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]
d1wwjd__d1r5pb___1			Cyanobacteria	Cyanobacteria	identical protein binding [GO:0042802]; circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]	circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]	circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]	circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]			identical protein binding [GO:0042802]	
d1wwra1_d3ex8c1__1			Aquificae	Firmicutes	tRNA-specific adenosine-34 deaminase complex [GO:0052718]; tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	tRNA wobble adenosine to inosine editing [GO:0002100]	riboflavin biosynthetic process [GO:0009231]	tRNA-specific adenosine-34 deaminase complex [GO:0052718]		tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d1wwrc2_d1ux1a___1			Aquificae	Firmicutes	tRNA-specific adenosine-34 deaminase complex [GO:0052718]; tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]	tRNA wobble adenosine to inosine editing [GO:0002100]	cytidine deamination [GO:0009972]	tRNA-specific adenosine-34 deaminase complex [GO:0052718]	cytosol [GO:0005829]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]
d1wwrd__d1alna2__1			Aquificae	Proteobacteria	tRNA-specific adenosine-34 deaminase complex [GO:0052718]; tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; pyrimidine nucleoside binding [GO:0001884]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; nucleobase-containing small molecule interconversion [GO:0015949]	tRNA wobble adenosine to inosine editing [GO:0002100]	cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; nucleobase-containing small molecule interconversion [GO:0015949]	tRNA-specific adenosine-34 deaminase complex [GO:0052718]	cytosol [GO:0005829]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; pyrimidine nucleoside binding [GO:0001884]; zinc ion binding [GO:0008270]
d1wwva1_d2y9ta1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell-cell junction [GO:0005911]; plasma membrane [GO:0005886]; protein binding, bridging [GO:0030674]; Ras protein signal transduction [GO:0007265]; Rho protein signal transduction [GO:0007266]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; rough endoplasmic reticulum [GO:0005791]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; WW domain binding [GO:0050699]; apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative cell aging [GO:0001302]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]	Ras protein signal transduction [GO:0007265]; Rho protein signal transduction [GO:0007266]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative cell aging [GO:0001302]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]	cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; rough endoplasmic reticulum [GO:0005791]	protein binding, bridging [GO:0030674]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; WW domain binding [GO:0050699]
d1wwwx__d1im9d1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1wwxa1_d1d8ja___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cell differentiation [GO:0030154]; ectodermal cell fate commitment [GO:0001712]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of cell differentiation [GO:0045596]; regulation of transcription by RNA polymerase II [GO:0006357]; somatic stem cell population maintenance [GO:0035019]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIE complex [GO:0005673]; DNA binding [GO:0003677]; RNA binding [GO:0003723]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cell differentiation [GO:0030154]; ectodermal cell fate commitment [GO:0001712]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of cell differentiation [GO:0045596]; regulation of transcription by RNA polymerase II [GO:0006357]; somatic stem cell population maintenance [GO:0035019]	snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIE complex [GO:0005673]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	DNA binding [GO:0003677]; RNA binding [GO:0003723]; RNA polymerase II general transcription initiation factor activity [GO:0016251]
d1wwza1_d4r87i___1			Euryarchaeota	Proteobacteria	N-acetyltransferase activity [GO:0008080]	cytoplasm [GO:0005737]; diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]; polyamine catabolic process [GO:0006598]		polyamine catabolic process [GO:0006598]		cytoplasm [GO:0005737]	N-acetyltransferase activity [GO:0008080]	diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]
d1wx0c__d4woqg___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	N-acetylneuraminate lyase activity [GO:0008747]
d1wx0d__d1fdjc___1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; microtubule organizing center [GO:0005815]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	fructose-bisphosphate aldolase activity [GO:0004332]
d1wx0e__d5hwma1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	5-dehydro-4-deoxyglucarate dehydratase activity [GO:0047448]; D-glucarate catabolic process [GO:0042838]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	D-glucarate catabolic process [GO:0042838]	cytoplasm [GO:0005737]		aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	5-dehydro-4-deoxyglucarate dehydratase activity [GO:0047448]
d1wx0g__d1hl2c___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d1wx0i__d1l6wi___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	fructose metabolic process [GO:0006000]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	fructose 6-phosphate aldolase activity [GO:0097023]
d1wx0j__d2qjga___1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; aromatic amino acid family biosynthetic process [GO:0009073]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	aromatic amino acid family biosynthetic process [GO:0009073]	cytoplasm [GO:0005737]		aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]
d1wx2a1_d4p6sb___1			Actinobacteria	Firmicutes	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d1wx3a1_d4hd4b___1				Firmicutes		metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]						metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d1wx9a1_d3r66c2__1	Metazoa	Metazoa	Chordata	Chordata	BAT3 complex [GO:0071818]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Hsp70 protein binding [GO:0030544]; identical protein binding [GO:0042802]; misfolded protein binding [GO:0051787]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ribosome binding [GO:0043022]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]; apoptotic process [GO:0006915]; brain development [GO:0007420]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; ER-associated misfolded protein catabolic process [GO:0071712]; immune response-activating cell surface receptor signaling pathway [GO:0002429]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; maintenance of unfolded protein involved in ERAD pathway [GO:1904378]; natural killer cell activation [GO:0030101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; positive regulation of ERAD pathway [GO:1904294]; proteasomal protein catabolic process [GO:0010498]; protein localization to cytosolic proteasome complex involved in ERAD pathway [GO:1904379]; protein stabilization [GO:0050821]; regulation of cell population proliferation [GO:0042127]; regulation of embryonic development [GO:0045995]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	apoptotic process [GO:0006915]; brain development [GO:0007420]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; ER-associated misfolded protein catabolic process [GO:0071712]; immune response-activating cell surface receptor signaling pathway [GO:0002429]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; maintenance of unfolded protein involved in ERAD pathway [GO:1904378]; natural killer cell activation [GO:0030101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; positive regulation of ERAD pathway [GO:1904294]; proteasomal protein catabolic process [GO:0010498]; protein localization to cytosolic proteasome complex involved in ERAD pathway [GO:1904379]; protein stabilization [GO:0050821]; regulation of cell population proliferation [GO:0042127]; regulation of embryonic development [GO:0045995]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	BAT3 complex [GO:0071818]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	Hsp70 protein binding [GO:0030544]; identical protein binding [GO:0042802]; misfolded protein binding [GO:0051787]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ribosome binding [GO:0043022]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1wxsa1_d1j0ga1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; brain development [GO:0007420]; negative regulation of apoptotic process [GO:0043066]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; response to endoplasmic reticulum stress [GO:0034976]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; brain development [GO:0007420]; negative regulation of apoptotic process [GO:0043066]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; response to endoplasmic reticulum stress [GO:0034976]	brain development [GO:0007420]; negative regulation of apoptotic process [GO:0043066]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; response to endoplasmic reticulum stress [GO:0034976]	brain development [GO:0007420]; negative regulation of apoptotic process [GO:0043066]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; response to endoplasmic reticulum stress [GO:0034976]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]		
d1wxsa1_d5chfe1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; brain development [GO:0007420]; negative regulation of apoptotic process [GO:0043066]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; response to endoplasmic reticulum stress [GO:0034976]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	brain development [GO:0007420]; negative regulation of apoptotic process [GO:0043066]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; response to endoplasmic reticulum stress [GO:0034976]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]		integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1wxya__d2qeed1__1	Metazoa		Chordata	Firmicutes	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]; adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	metal ion binding [GO:0046872]	adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]		cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]		adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1wxza__d1fkxa___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]; adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; in utero embryonic development [GO:0001701]; inosine biosynthetic process [GO:0046103]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]	adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]	cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]	adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]
d1wy8a1_d5tl6a___1	Metazoa	Metazoa	Chordata	Chordata	nuclear heterochromatin [GO:0005720]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; histone binding [GO:0042393]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; maintenance of DNA methylation [GO:0010216]; positive regulation of cell cycle arrest [GO:0071158]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; maintenance of DNA methylation [GO:0010216]; positive regulation of cell cycle arrest [GO:0071158]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	nuclear heterochromatin [GO:0005720]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; histone binding [GO:0042393]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1wyec__d4c5mb1__1			Crenarchaeota	Firmicutes	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; phosphomethylpyrimidine kinase activity [GO:0008972]; thiamine biosynthetic process [GO:0009228]		thiamine biosynthetic process [GO:0009228]			2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; phosphomethylpyrimidine kinase activity [GO:0008972]
d1wyef__d1td2a___1			Crenarchaeota	Proteobacteria	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; pyridoxal kinase activity [GO:0008478]; pyridoxal 5'-phosphate salvage [GO:0009443]; pyridoxal metabolic process [GO:0042817]; vitamin B6 biosynthetic process [GO:0042819]		pyridoxal 5'-phosphate salvage [GO:0009443]; pyridoxal metabolic process [GO:0042817]; vitamin B6 biosynthetic process [GO:0042819]		cytosol [GO:0005829]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; pyridoxal kinase activity [GO:0008478]
d1wyia__d2ypib___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	triose-phosphate isomerase activity [GO:0004807]
d1wyib__d4iota___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	triose-phosphate isomerase activity [GO:0004807]
d1wyka__d1vcpb___1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1wykb__d1gj7.1__1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	serine-type endopeptidase activity [GO:0004252]
d1wykb__d5eqqa1__1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; transformation of host cell by virus [GO:0019087]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	transformation of host cell by virus [GO:0019087]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]		RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d1wyqa1_d4q59a2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic spectrin-associated cytoskeleton [GO:0099189]; presynapse [GO:0098793]; spectrin [GO:0008091]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; phospholipid binding [GO:0005543]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of synapse [GO:0098918]; actin filament capping [GO:0051693]; adult behavior [GO:0030534]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; axon guidance [GO:0007411]; cerebellar Purkinje cell layer morphogenesis [GO:0021692]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]; multicellular organism growth [GO:0035264]; postsynapse organization [GO:0099173]; synapse assembly [GO:0007416]; vesicle-mediated transport [GO:0016192]	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	actin filament capping [GO:0051693]; adult behavior [GO:0030534]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; axon guidance [GO:0007411]; cerebellar Purkinje cell layer morphogenesis [GO:0021692]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]; multicellular organism growth [GO:0035264]; postsynapse organization [GO:0099173]; synapse assembly [GO:0007416]; vesicle-mediated transport [GO:0016192]	hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic spectrin-associated cytoskeleton [GO:0099189]; presynapse [GO:0098793]; spectrin [GO:0008091]	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; phospholipid binding [GO:0005543]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of synapse [GO:0098918]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]
d1wyra1_d1h67a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; lamellipodium [GO:0030027]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; apoptotic process [GO:0006915]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; lamellipodium assembly [GO:0030032]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	actin binding [GO:0003779]; calmodulin binding [GO:0005516]; actomyosin structure organization [GO:0031032]	apoptotic process [GO:0006915]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; lamellipodium assembly [GO:0030032]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	actomyosin structure organization [GO:0031032]	cytosol [GO:0005829]; lamellipodium [GO:0030027]		GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]	actin binding [GO:0003779]; calmodulin binding [GO:0005516]
d1wyta1_d1c7gb___1			Deinococcus-Thermus	Proteobacteria	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	tyrosine metabolic process [GO:0006570]		cytoplasm [GO:0005737]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]	tyrosine phenol-lyase activity [GO:0050371]
d1wytd__d1i48f___1		Viridiplantae	Deinococcus-Thermus	Streptophyta	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	transsulfuration [GO:0019346]			glycine dehydrogenase (decarboxylating) activity [GO:0004375]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d1wyua__d4r5zd1__1			Deinococcus-Thermus	Actinobacteria	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	histidine biosynthetic process [GO:0000105]			glycine dehydrogenase (decarboxylating) activity [GO:0004375]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]
d1wyud__d5vwqg___1			Deinococcus-Thermus	Proteobacteria	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1wyue__d2dgke___1			Deinococcus-Thermus	Proteobacteria	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]
d1wyuf__d1wytc___1			Deinococcus-Thermus	Deinococcus-Thermus	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]			glycine dehydrogenase (decarboxylating) activity [GO:0004375]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]
d1wyug__d5w71b___1			Deinococcus-Thermus	Firmicutes	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	transaminase activity [GO:0008483]; antibiotic biosynthetic process [GO:0017000]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	antibiotic biosynthetic process [GO:0017000]			glycine dehydrogenase (decarboxylating) activity [GO:0004375]	transaminase activity [GO:0008483]
d1wyvb__d4wxbd___1			Deinococcus-Thermus	Firmicutes	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]		cytoplasm [GO:0005737]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]
d1wyve__d1amsa___1			Deinococcus-Thermus	Proteobacteria	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1wyvg__d1czea___1			Deinococcus-Thermus	Proteobacteria	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d1wyvh__d4ba5a___1			Deinococcus-Thermus	Proteobacteria	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]				glycine dehydrogenase (decarboxylating) activity [GO:0004375]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]
d1wywa__d4ws3a___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]	uracil DNA N-glycosylase activity [GO:0004844]
d1wz0a1_d1p1aa1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; XPC complex [GO:0071942]; damaged DNA binding [GO:0003684]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded DNA binding [GO:0003697]; ubiquitin binding [GO:0043130]; cellular response to interleukin-7 [GO:0098761]; embryonic organ development [GO:0048568]; global genome nucleotide-excision repair [GO:0070911]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; spermatogenesis [GO:0007283]	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	cellular response to interleukin-7 [GO:0098761]; embryonic organ development [GO:0048568]; global genome nucleotide-excision repair [GO:0070911]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; spermatogenesis [GO:0007283]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; XPC complex [GO:0071942]	RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]	damaged DNA binding [GO:0003684]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded DNA binding [GO:0003697]; ubiquitin binding [GO:0043130]
d1wz1h__d3ncma1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; commissural neuron axon guidance [GO:0071679]; homotypic cell-cell adhesion [GO:0034109]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of exocyst assembly [GO:0001928]; regulation of semaphorin-plexin signaling pathway [GO:2001260]; regulation of sensory perception of pain [GO:0051930]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	aging [GO:0007568]; axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; commissural neuron axon guidance [GO:0071679]; homotypic cell-cell adhesion [GO:0034109]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of exocyst assembly [GO:0001928]; regulation of semaphorin-plexin signaling pathway [GO:2001260]; regulation of sensory perception of pain [GO:0051930]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	antigen binding [GO:0003823]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]
d1wz1l__d3o81b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]	antigen binding [GO:0003823]	protein homodimerization activity [GO:0042803]
d1wz8d__d5g1sg___1			Deinococcus-Thermus	Proteobacteria	catalytic activity [GO:0003824]	cytoplasm [GO:0005737]; serine-type endopeptidase activity [GO:0004252]				cytoplasm [GO:0005737]	catalytic activity [GO:0003824]	serine-type endopeptidase activity [GO:0004252]
d1wzaa2_d1e72m___1		Viridiplantae	Firmicutes	Streptophyta	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		vacuole [GO:0005773]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]
d1wzea1_d2ldxa1__1		Metazoa	Deinococcus-Thermus	Chordata	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]; L-lactate dehydrogenase activity [GO:0004459]; ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]		cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d1wzea1_d3aogh2__1			Deinococcus-Thermus	Deinococcus-Thermus	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cellular amino acid metabolic process [GO:0006520]			L-malate dehydrogenase activity [GO:0030060]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1wzeb2_d3d4pa2__1			Deinococcus-Thermus	Firmicutes	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d1wzia1_d1psda1__1			Deinococcus-Thermus	Proteobacteria	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	L-serine biosynthetic process [GO:0006564]		cytosol [GO:0005829]	L-malate dehydrogenase activity [GO:0030060]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]
d1wzka2_d1g94a1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d1wzkb2_d1xsjf3__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1wzkb3_d3lx9b1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d1wzla1_d3weaa___1		Metazoa	Firmicutes	Arthropoda	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	
d1wzla1_d8cgta1__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1wzla3_d1e4nb___1		Viridiplantae	Firmicutes	Streptophyta	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]		chloroplast [GO:0009507]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]
d1wzmb1_d4yeec1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]	carbohydrate metabolic process [GO:0005975]	fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]		apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]
d1wzmb3_d1j18a2__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1wzmb3_d4gzia___1		Viridiplantae	Firmicutes	Streptophyta	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]
d1wzva1_d5tuta1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; ubiquitin ligase complex [GO:0000151]; ISG15 transferase activity [GO:0042296]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; ISG15-protein conjugation [GO:0032020]; negative regulation of type I interferon production [GO:0032480]; translesion synthesis [GO:0019985]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; ISG15-protein conjugation [GO:0032020]; negative regulation of type I interferon production [GO:0032480]; translesion synthesis [GO:0019985]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; ubiquitin ligase complex [GO:0000151]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ISG15 transferase activity [GO:0042296]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1wzxa1_d1bglc3__1			Firmicutes		cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]				cellulase activity [GO:0008810]; metal ion binding [GO:0046872]	
d1wzya__d1pf8a___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; azurophil granule lumen [GO:0035578]; caveola [GO:0005901]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; early endosome [GO:0005769]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; microtubule organizing center [GO:0005815]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; pseudopodium [GO:0031143]; ATP binding [GO:0005524]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; MAP kinase activity [GO:0004707]; MAP kinase kinase activity [GO:0004708]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; phosphatase binding [GO:0019902]; phosphotyrosine residue binding [GO:0001784]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription factor binding [GO:0008134]; activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; aging [GO:0007568]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiac neural crest cell development involved in heart development [GO:0061308]; caveolin-mediated endocytosis [GO:0072584]; cell cycle [GO:0007049]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to organic substance [GO:0071310]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; chemical synaptic transmission [GO:0007268]; chemotaxis [GO:0006935]; cytosine metabolic process [GO:0019858]; decidualization [GO:0046697]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERBB signaling pathway [GO:0038127]; ERK1 and ERK2 cascade [GO:0070371]; face development [GO:0060324]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; learning or memory [GO:0007611]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; long-term synaptic potentiation [GO:0060291]; lung morphogenesis [GO:0060425]; mammary gland epithelial cell proliferation [GO:0033598]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; neutrophil degranulation [GO:0043312]; outer ear morphogenesis [GO:0042473]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; protein phosphorylation [GO:0006468]; regulation of cellular pH [GO:0030641]; regulation of cellular response to heat [GO:1900034]; regulation of cytoskeleton organization [GO:0051493]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of gene expression [GO:0010468]; regulation of Golgi inheritance [GO:0090170]; regulation of ossification [GO:0030278]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of protein stability [GO:0031647]; regulation of stress-activated MAPK cascade [GO:0032872]; response to epidermal growth factor [GO:0070849]; response to estrogen [GO:0043627]; response to exogenous dsRNA [GO:0043330]; response to nicotine [GO:0035094]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea formation [GO:0060440]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; aging [GO:0007568]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiac neural crest cell development involved in heart development [GO:0061308]; caveolin-mediated endocytosis [GO:0072584]; cell cycle [GO:0007049]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to organic substance [GO:0071310]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; chemical synaptic transmission [GO:0007268]; chemotaxis [GO:0006935]; cytosine metabolic process [GO:0019858]; decidualization [GO:0046697]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERBB signaling pathway [GO:0038127]; ERK1 and ERK2 cascade [GO:0070371]; face development [GO:0060324]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; learning or memory [GO:0007611]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; long-term synaptic potentiation [GO:0060291]; lung morphogenesis [GO:0060425]; mammary gland epithelial cell proliferation [GO:0033598]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; neutrophil degranulation [GO:0043312]; outer ear morphogenesis [GO:0042473]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; protein phosphorylation [GO:0006468]; regulation of cellular pH [GO:0030641]; regulation of cellular response to heat [GO:1900034]; regulation of cytoskeleton organization [GO:0051493]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of gene expression [GO:0010468]; regulation of Golgi inheritance [GO:0090170]; regulation of ossification [GO:0030278]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of protein stability [GO:0031647]; regulation of stress-activated MAPK cascade [GO:0032872]; response to epidermal growth factor [GO:0070849]; response to estrogen [GO:0043627]; response to exogenous dsRNA [GO:0043330]; response to nicotine [GO:0035094]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea formation [GO:0060440]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	axon [GO:0030424]; azurophil granule lumen [GO:0035578]; caveola [GO:0005901]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; early endosome [GO:0005769]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; microtubule organizing center [GO:0005815]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; pseudopodium [GO:0031143]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; MAP kinase activity [GO:0004707]; MAP kinase kinase activity [GO:0004708]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; phosphatase binding [GO:0019902]; phosphotyrosine residue binding [GO:0001784]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d1x06a__d2vfwa___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; Gram-negative-bacterium-type cell wall biogenesis [GO:0043164]; peptidoglycan biosynthetic process [GO:0009252]; polyprenol biosynthetic process [GO:0016094]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]; Z-farnesyl diphosphate synthase activity [GO:0033850]; polyprenol biosynthetic process [GO:0016094]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; Gram-negative-bacterium-type cell wall biogenesis [GO:0043164]; peptidoglycan biosynthetic process [GO:0009252]; polyprenol biosynthetic process [GO:0016094]; regulation of cell shape [GO:0008360]	polyprenol biosynthetic process [GO:0016094]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]	di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]; Z-farnesyl diphosphate synthase activity [GO:0033850]
d1x07a__d2vg1a___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; Gram-negative-bacterium-type cell wall biogenesis [GO:0043164]; peptidoglycan biosynthetic process [GO:0009252]; polyprenol biosynthetic process [GO:0016094]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]; Z-farnesyl diphosphate synthase activity [GO:0033850]; polyprenol biosynthetic process [GO:0016094]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; Gram-negative-bacterium-type cell wall biogenesis [GO:0043164]; peptidoglycan biosynthetic process [GO:0009252]; polyprenol biosynthetic process [GO:0016094]; regulation of cell shape [GO:0008360]	polyprenol biosynthetic process [GO:0016094]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]	di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]; Z-farnesyl diphosphate synthase activity [GO:0033850]
d1x09a__d2vg1b___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; Gram-negative-bacterium-type cell wall biogenesis [GO:0043164]; peptidoglycan biosynthetic process [GO:0009252]; polyprenol biosynthetic process [GO:0016094]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]; Z-farnesyl diphosphate synthase activity [GO:0033850]; polyprenol biosynthetic process [GO:0016094]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; Gram-negative-bacterium-type cell wall biogenesis [GO:0043164]; peptidoglycan biosynthetic process [GO:0009252]; polyprenol biosynthetic process [GO:0016094]; regulation of cell shape [GO:0008360]	polyprenol biosynthetic process [GO:0016094]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]	di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]; Z-farnesyl diphosphate synthase activity [GO:0033850]
d1x0cb2_d2ntbb___1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; isopullulanase activity [GO:0051675]; metabolic process [GO:0008152]	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	metabolic process [GO:0008152]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	isopullulanase activity [GO:0051675]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]
d1x0gc__d1s98b___1			Cyanobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]; protein maturation by iron-sulfur cluster transfer [GO:0097428]	cytosol [GO:0005829]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; structural molecule activity [GO:0005198]; iron-sulfur cluster assembly [GO:0016226]; protein maturation by iron-sulfur cluster transfer [GO:0097428]	protein maturation by iron-sulfur cluster transfer [GO:0097428]	iron-sulfur cluster assembly [GO:0016226]; protein maturation by iron-sulfur cluster transfer [GO:0097428]		cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; structural molecule activity [GO:0005198]
d1x0la__d2y42d1__1			Deinococcus-Thermus	Deinococcus-Thermus	homoisocitrate dehydrogenase activity [GO:0047046]; metal ion binding [GO:0046872]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	lysine biosynthetic process via aminoadipic acid [GO:0019878]	leucine biosynthetic process [GO:0009098]		cytoplasm [GO:0005737]	homoisocitrate dehydrogenase activity [GO:0047046]; metal ion binding [GO:0046872]	3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1x0pd__d4oj3b___1			Cyanobacteria	Crenarchaeota	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	acylphosphatase activity [GO:0003998]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	acylphosphatase activity [GO:0003998]
d1x0pf__d2w4dd___1			Cyanobacteria	Euryarchaeota	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]
d1x0pg__d1w2ib___1			Cyanobacteria	Euryarchaeota	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]
d1x0pg__d2buna1__1			Cyanobacteria	Proteobacteria	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]
d1x0ub1_d4ryfg___1			Crenarchaeota	Firmicutes	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; propionyl-CoA carboxylase activity [GO:0004658]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	fatty acid biosynthetic process [GO:0006633]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	acetyl-CoA carboxylase complex [GO:0009317]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	acetyl-CoA carboxylase activity [GO:0003989]; propionyl-CoA carboxylase activity [GO:0004658]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d1x0ud1_d3tvua1__1		Fungi	Crenarchaeota	Ascomycota	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; propionyl-CoA carboxylase activity [GO:0004658]; fatty acid biosynthetic process [GO:0006633]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	fatty acid biosynthetic process [GO:0006633]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	acetyl-CoA carboxylase complex [GO:0009317]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	acetyl-CoA carboxylase activity [GO:0003989]; propionyl-CoA carboxylase activity [GO:0004658]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d1x10c__d1z8tb___1			Euryarchaeota	Euryarchaeota	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d1x10c__d4hpsd___1			Euryarchaeota	Proteobacteria	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d1x1ga1_d1v88a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; lamellipodium membrane [GO:0031258]; plasma membrane [GO:0005886]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]	cortical endoplasmic reticulum [GO:0032541]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; cholesterol binding [GO:0015485]; lipid binding [GO:0008289]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylserine binding [GO:0001786]; phosphatidylserine transfer activity [GO:0140343]; phospholipid transporter activity [GO:0005548]; sterol binding [GO:0032934]; activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid transport [GO:0015914]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204]	actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]	activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid transport [GO:0015914]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; lamellipodium membrane [GO:0031258]; plasma membrane [GO:0005886]	cortical endoplasmic reticulum [GO:0032541]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nuclear membrane [GO:0031965]	phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]	cholesterol binding [GO:0015485]; lipid binding [GO:0008289]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylserine binding [GO:0001786]; phosphatidylserine transfer activity [GO:0140343]; phospholipid transporter activity [GO:0005548]; sterol binding [GO:0032934]
d1x1ha1_d2brwb1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	polysaccharide metabolic process [GO:0005976]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d1x1ha3_d2brwb3__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	polysaccharide metabolic process [GO:0005976]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d1x1ha3_d3t09b5__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide metabolic process [GO:0005976]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1x1ia3_d1jz8a4__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide metabolic process [GO:0005976]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1x1ja3_d1jz7a4__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]; polysaccharide metabolic process [GO:0005976]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide metabolic process [GO:0005976]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; xanthan lyase activity [GO:0047492]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1x1na1_d3baka2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	amyloplast [GO:0009501]; chloroplast [GO:0009507]; 4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	amyloplast [GO:0009501]; chloroplast [GO:0009507]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1x1oa1_d3l0gd1__1			Deinococcus-Thermus	Proteobacteria	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]			nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1x1ob1_d1qpof2__1			Deinococcus-Thermus	Actinobacteria	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1x1ra1_d5uwua___1	Metazoa	Metazoa	Chordata	Chordata	plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; cellular response to leukemia inhibitory factor [GO:1990830]; Ras protein signal transduction [GO:0007265]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cellular response to leukemia inhibitory factor [GO:1990830]; Ras protein signal transduction [GO:0007265]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	plasma membrane [GO:0005886]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1x1ua__d3agoa___1		Fungi	Firmicutes	Basidiomycota	cytoplasm [GO:0005737]	endoribonuclease activity [GO:0004521]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]			cytoplasm [GO:0005737]			endoribonuclease activity [GO:0004521]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d1x1ub__d3whoa___1		Fungi	Firmicutes	Basidiomycota	cytoplasm [GO:0005737]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cytoplasm [GO:0005737]			endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1x1uc__d1ucia___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d1x1vb__d5xfhb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d1x1wb__d1jbsa___1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]; negative regulation of translation [GO:0017148]		negative regulation of translation [GO:0017148]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1x1xd1_d1b2uf___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1x1ya__d1yvsa___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1x1yc__d1bnea___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d1x27f2_d1cj1h___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; protein domain specific binding [GO:0019904]; SH3 domain binding [GO:0017124]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament reorganization [GO:0090527]; antigen receptor-mediated signaling pathway [GO:0050851]; B cell receptor signaling pathway [GO:0050853]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to endothelin [GO:1990859]; cellular response to nitric oxide [GO:0071732]; epidermal growth factor receptor signaling pathway [GO:0007173]; G protein-coupled receptor signaling pathway [GO:0007186]; insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell migration [GO:0030335]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament reorganization [GO:0090527]; antigen receptor-mediated signaling pathway [GO:0050851]; B cell receptor signaling pathway [GO:0050853]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to endothelin [GO:1990859]; cellular response to nitric oxide [GO:0071732]; epidermal growth factor receptor signaling pathway [GO:0007173]; G protein-coupled receptor signaling pathway [GO:0007186]; insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell migration [GO:0030335]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ruffle [GO:0001726]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	protein domain specific binding [GO:0019904]; SH3 domain binding [GO:0017124]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]
d1x29a__d5xmqa___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d1x29b__d1i41g___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d1x2aa__d1i43b___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d1x2ba__d1mu0a___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]	aminopeptidase activity [GO:0004177]			cytoplasm [GO:0005737]		aminopeptidase activity [GO:0004177]	aminopeptidase activity [GO:0004177]
d1x2ea__d1xrpa___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]	aminopeptidase activity [GO:0004177]			cytoplasm [GO:0005737]		aminopeptidase activity [GO:0004177]	aminopeptidase activity [GO:0004177]
d1x2ra__d4l7cb1__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cell-cell adherens junction [GO:0005913]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]; cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of gene expression [GO:0010629]; protein complex oligomerization [GO:0051259]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]; cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of gene expression [GO:0010629]; protein complex oligomerization [GO:0051259]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]	cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	actin filament [GO:0005884]; cell-cell adherens junction [GO:0005913]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]	disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]	disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]
d1x2ta__d3ncxa2__1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	
d1x2td__d4gjxe___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d1x2wa__d4j6lh___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d1x2wa__d5jq1a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; asialoglycoprotein receptor activity [GO:0004873]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular response to extracellular stimulus [GO:0031668]; protein N-linked glycosylation via asparagine [GO:0018279]; receptor-mediated endocytosis [GO:0006898]; viral process [GO:0016032]		cellular response to extracellular stimulus [GO:0031668]; protein N-linked glycosylation via asparagine [GO:0018279]; receptor-mediated endocytosis [GO:0006898]; viral process [GO:0016032]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	asialoglycoprotein receptor activity [GO:0004873]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d1x3eb__d2n8na___1			Actinobacteria	Firmicutes	single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]	cytosol [GO:0005829]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation initiation factor activity [GO:0003743]	DNA replication [GO:0006260]			cytosol [GO:0005829]	single-stranded DNA binding [GO:0003697]	ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation initiation factor activity [GO:0003743]
d1x3ma1_d1tuub2__1			Proteobacteria	Euryarchaeota	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]; L-threonine catabolic process to propionate [GO:0070689]	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	L-threonine catabolic process to propionate [GO:0070689]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]
d1x3na1_d1x9jc2__1			Proteobacteria	Thermotogae	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]; L-threonine catabolic process to propionate [GO:0070689]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	L-threonine catabolic process to propionate [GO:0070689]			cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]	ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]
d1x3na1_d2yjeb2__1		Metazoa	Proteobacteria	Chordata	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]; L-threonine catabolic process to propionate [GO:0070689]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	L-threonine catabolic process to propionate [GO:0070689]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d1x44a1_d1rjzb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; myofibril [GO:0030016]; myosin filament [GO:0032982]; actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cytosol [GO:0005829]; myofibril [GO:0030016]; myosin filament [GO:0032982]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1x45a1_d2v90f___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; amyloid-beta binding [GO:0001540]; axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytosol [GO:0005829]; subapical complex [GO:0035003]; guanylate cyclase inhibitor activity [GO:0030251]; ion channel inhibitor activity [GO:0008200]; protein C-terminus binding [GO:0008022]; ubiquitin-specific protease binding [GO:1990381]; ion transport [GO:0006811]; negative regulation of cGMP-mediated signaling [GO:0010754]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to toxic substance [GO:0009636]; water transport [GO:0006833]	axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; intracellular protein transport [GO:0006886]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	ion transport [GO:0006811]; negative regulation of cGMP-mediated signaling [GO:0010754]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to toxic substance [GO:0009636]; water transport [GO:0006833]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytosol [GO:0005829]; subapical complex [GO:0035003]	amyloid-beta binding [GO:0001540]	guanylate cyclase inhibitor activity [GO:0030251]; ion channel inhibitor activity [GO:0008200]; protein C-terminus binding [GO:0008022]; ubiquitin-specific protease binding [GO:1990381]
d1x48a1_d1stua___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; eukaryotic translation initiation factor 2alpha kinase activity [GO:0004694]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; activation of MAPKK activity [GO:0000186]; cellular response to amino acid starvation [GO:0034198]; defense response to virus [GO:0051607]; endoplasmic reticulum unfolded protein response [GO:0030968]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of translation [GO:0017148]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic process [GO:0043065]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of NLRP3 inflammasome complex assembly [GO:1900225]; response to interferon-alpha [GO:0035455]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; response to vitamin E [GO:0033197]; translation [GO:0006412]	apical cortex [GO:0045179]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basal cortex [GO:0045180]; basal plasma membrane [GO:0009925]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; germ plasm [GO:0060293]; messenger ribonucleoprotein complex [GO:1990124]; neuronal cell body [GO:0043025]; neuronal ribonucleoprotein granule [GO:0071598]; P-body [GO:0000932]; subsynaptic reticulum [GO:0071212]; double-stranded RNA binding [GO:0003725]; microtubule binding [GO:0008017]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; anterior/posterior axis specification, embryo [GO:0008595]; asymmetric neuroblast division [GO:0055059]; asymmetric protein localization involved in cell fate determination [GO:0045167]; bicoid mRNA localization [GO:0045450]; intracellular mRNA localization [GO:0008298]; long-term memory [GO:0007616]; neuroblast fate determination [GO:0007400]; oogenesis [GO:0048477]; pole plasm assembly [GO:0007315]; pole plasm oskar mRNA localization [GO:0045451]; pole plasm protein localization [GO:0007318]; pole plasm RNA localization [GO:0007316]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of oskar mRNA translation [GO:0046012]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; protein localization [GO:0008104]; protein localization to synapse [GO:0035418]; regulation of oskar mRNA translation [GO:0046011]; regulation of pole plasm oskar mRNA localization [GO:0007317]; RNA localization [GO:0006403]	activation of MAPKK activity [GO:0000186]; cellular response to amino acid starvation [GO:0034198]; defense response to virus [GO:0051607]; endoplasmic reticulum unfolded protein response [GO:0030968]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of translation [GO:0017148]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic process [GO:0043065]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of NLRP3 inflammasome complex assembly [GO:1900225]; response to interferon-alpha [GO:0035455]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; response to vitamin E [GO:0033197]; translation [GO:0006412]	anterior/posterior axis specification, embryo [GO:0008595]; asymmetric neuroblast division [GO:0055059]; asymmetric protein localization involved in cell fate determination [GO:0045167]; bicoid mRNA localization [GO:0045450]; intracellular mRNA localization [GO:0008298]; long-term memory [GO:0007616]; neuroblast fate determination [GO:0007400]; oogenesis [GO:0048477]; pole plasm assembly [GO:0007315]; pole plasm oskar mRNA localization [GO:0045451]; pole plasm protein localization [GO:0007318]; pole plasm RNA localization [GO:0007316]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of oskar mRNA translation [GO:0046012]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; protein localization [GO:0008104]; protein localization to synapse [GO:0035418]; regulation of oskar mRNA translation [GO:0046011]; regulation of pole plasm oskar mRNA localization [GO:0007317]; RNA localization [GO:0006403]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	apical cortex [GO:0045179]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basal cortex [GO:0045180]; basal plasma membrane [GO:0009925]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; germ plasm [GO:0060293]; messenger ribonucleoprotein complex [GO:1990124]; neuronal cell body [GO:0043025]; neuronal ribonucleoprotein granule [GO:0071598]; P-body [GO:0000932]; subsynaptic reticulum [GO:0071212]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; eukaryotic translation initiation factor 2alpha kinase activity [GO:0004694]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]	double-stranded RNA binding [GO:0003725]; microtubule binding [GO:0008017]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1x49a1_d1x47a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; eukaryotic translation initiation factor 2alpha kinase activity [GO:0004694]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; activation of MAPKK activity [GO:0000186]; cellular response to amino acid starvation [GO:0034198]; defense response to virus [GO:0051607]; endoplasmic reticulum unfolded protein response [GO:0030968]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of translation [GO:0017148]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic process [GO:0043065]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of NLRP3 inflammasome complex assembly [GO:1900225]; response to interferon-alpha [GO:0035455]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; response to vitamin E [GO:0033197]; translation [GO:0006412]	cytoplasm [GO:0005737]; microprocessor complex [GO:0070877]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; double-stranded RNA binding [GO:0003725]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; miRNA metabolic process [GO:0010586]; primary miRNA processing [GO:0031053]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	activation of MAPKK activity [GO:0000186]; cellular response to amino acid starvation [GO:0034198]; defense response to virus [GO:0051607]; endoplasmic reticulum unfolded protein response [GO:0030968]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of translation [GO:0017148]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic process [GO:0043065]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of NLRP3 inflammasome complex assembly [GO:1900225]; response to interferon-alpha [GO:0035455]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; response to vitamin E [GO:0033197]; translation [GO:0006412]	miRNA metabolic process [GO:0010586]; primary miRNA processing [GO:0031053]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cytoplasm [GO:0005737]; microprocessor complex [GO:0070877]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; eukaryotic translation initiation factor 2alpha kinase activity [GO:0004694]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]	double-stranded RNA binding [GO:0003725]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]
d1x4fa1_d2e5ia1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; zinc ion binding [GO:0008270]; activation of innate immune response [GO:0002218]; blastocyst formation [GO:0001825]; heart valve development [GO:0003170]; innate immune response [GO:0045087]; posttranscriptional regulation of gene expression [GO:0010608]; ventricular septum development [GO:0003281]	nucleus [GO:0005634]; mRNA binding [GO:0003729]; mRNA processing [GO:0006397]; positive regulation of RNA splicing [GO:0033120]	activation of innate immune response [GO:0002218]; blastocyst formation [GO:0001825]; heart valve development [GO:0003170]; innate immune response [GO:0045087]; posttranscriptional regulation of gene expression [GO:0010608]; ventricular septum development [GO:0003281]	mRNA processing [GO:0006397]; positive regulation of RNA splicing [GO:0033120]	cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]	nucleus [GO:0005634]	identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; zinc ion binding [GO:0008270]	mRNA binding [GO:0003729]
d1x4ha1_d2cq1a1__1	Metazoa	Metazoa	Chordata	Chordata	nucleolus [GO:0005730]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; RNA binding [GO:0003723]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	nucleolus [GO:0005730]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]	RNA binding [GO:0003723]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d1x4xa1_d5komc___1	Metazoa		Chordata	Proteobacteria	acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; vesicle membrane [GO:0012506]; RNA binding [GO:0003723]; cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286]	integral component of plasma membrane [GO:0005887]; inorganic anion transmembrane transporter activity [GO:0015103]	cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286]		acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; vesicle membrane [GO:0012506]	integral component of plasma membrane [GO:0005887]	RNA binding [GO:0003723]	inorganic anion transmembrane transporter activity [GO:0015103]
d1x5ba1_d1py1b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; ESCRT-0 complex [GO:0033565]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; macroautophagy [GO:0016236]; membrane organization [GO:0061024]; multivesicular body assembly [GO:0036258]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; protein deubiquitination [GO:0016579]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; macroautophagy [GO:0016236]; membrane organization [GO:0061024]; multivesicular body assembly [GO:0036258]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; protein deubiquitination [GO:0016579]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; ESCRT-0 complex [GO:0033565]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d1x5ca1_d3zvjl1__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; procollagen-proline 4-dioxygenase complex [GO:0016222]; enzyme binding [GO:0019899]; integrin binding [GO:0005178]; peptide disulfide oxidoreductase activity [GO:0015037]; procollagen-proline 4-dioxygenase activity [GO:0004656]; protein disulfide isomerase activity [GO:0003756]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-7 [GO:0098761]; chylomicron assembly [GO:0034378]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; protein folding [GO:0006457]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976]; very-low-density lipoprotein particle assembly [GO:0034379]	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-7 [GO:0098761]; chylomicron assembly [GO:0034378]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; protein folding [GO:0006457]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976]; very-low-density lipoprotein particle assembly [GO:0034379]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; procollagen-proline 4-dioxygenase complex [GO:0016222]	cell [GO:0005623]	enzyme binding [GO:0019899]; integrin binding [GO:0005178]; peptide disulfide oxidoreductase activity [GO:0015037]; procollagen-proline 4-dioxygenase activity [GO:0004656]; protein disulfide isomerase activity [GO:0003756]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1x5da1_d2o85a___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; plasma membrane [GO:0005886]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; IRE1-mediated unfolded protein response [GO:0036498]; post-translational protein modification [GO:0043687]; protein folding [GO:0006457]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; IRE1-mediated unfolded protein response [GO:0036498]; post-translational protein modification [GO:0043687]; protein folding [GO:0006457]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; plasma membrane [GO:0005886]	cell [GO:0005623]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide isomerase activity [GO:0003756]	protein disulfide oxidoreductase activity [GO:0015035]
d1x5la1_d4lpte1__1	Metazoa		Chordata		early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; GPI-linked ephrin receptor activity [GO:0005004]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; ephrin receptor signaling pathway [GO:0048013]; neuron projection development [GO:0031175]; neuron remodeling [GO:0016322]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; substrate-dependent cell migration [GO:0006929]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; ephrin receptor signaling pathway [GO:0048013]; neuron projection development [GO:0031175]; neuron remodeling [GO:0016322]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; substrate-dependent cell migration [GO:0006929]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; GPI-linked ephrin receptor activity [GO:0005004]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	
d1x5na1_d2i0ib1__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; microvillus [GO:0005902]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; stereocilia ankle link [GO:0002141]; stereocilia ankle link complex [GO:0002142]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426]; synapse [GO:0045202]; actin filament binding [GO:0051015]; spectrin binding [GO:0030507]; actin filament bundle assembly [GO:0051017]; brush border assembly [GO:1904970]; cellular protein-containing complex assembly [GO:0034622]; equilibrioception [GO:0050957]; G2/M transition of mitotic cell cycle [GO:0000086]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell stereocilium organization [GO:0060122]; parallel actin filament bundle assembly [GO:0030046]; photoreceptor cell maintenance [GO:0045494]; protein localization to microvillus [GO:1904106]; regulation of microvillus length [GO:0032532]; retinal cone cell development [GO:0046549]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	actin filament bundle assembly [GO:0051017]; brush border assembly [GO:1904970]; cellular protein-containing complex assembly [GO:0034622]; equilibrioception [GO:0050957]; G2/M transition of mitotic cell cycle [GO:0000086]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell stereocilium organization [GO:0060122]; parallel actin filament bundle assembly [GO:0030046]; photoreceptor cell maintenance [GO:0045494]; protein localization to microvillus [GO:1904106]; regulation of microvillus length [GO:0032532]; retinal cone cell development [GO:0046549]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; microvillus [GO:0005902]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; stereocilia ankle link [GO:0002141]; stereocilia ankle link complex [GO:0002142]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426]; synapse [GO:0045202]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]	actin filament binding [GO:0051015]; spectrin binding [GO:0030507]	ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]
d1x5oa1_d2mqpa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; ribonucleoprotein complex [GO:1990904]; ribonucleoprotein granule [GO:0035770]; mRNA 3'-UTR binding [GO:0003730]; mRNA CDS binding [GO:1990715]; pre-mRNA intronic binding [GO:0097157]; transcription regulatory region DNA binding [GO:0044212]; cellular response to amino acid starvation [GO:0034198]; circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to peptide [GO:1901652]	DNA replication [GO:0006260]; RNA processing [GO:0006396]	cellular response to amino acid starvation [GO:0034198]; circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to peptide [GO:1901652]	cytosol [GO:0005829]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; ribonucleoprotein complex [GO:1990904]; ribonucleoprotein granule [GO:0035770]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]	mRNA 3'-UTR binding [GO:0003730]; mRNA CDS binding [GO:1990715]; pre-mRNA intronic binding [GO:0097157]; transcription regulatory region DNA binding [GO:0044212]
d1x5qa1_d1te0a1__1	Metazoa		Chordata	Proteobacteria	basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; myelin sheath abaxonal region [GO:0035748]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Scrib-APC-beta-catenin complex [GO:0034750]; synapse [GO:0045202]; cadherin binding [GO:0045296]; activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; auditory receptor cell stereocilium organization [GO:0060088]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; post-anal tail morphogenesis [GO:0036342]; protein localization to adherens junction [GO:0071896]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; wound healing [GO:0042060]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; auditory receptor cell stereocilium organization [GO:0060088]; cell-cell adhesion [GO:0098609]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; post-anal tail morphogenesis [GO:0036342]; protein localization to adherens junction [GO:0071896]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; wound healing [GO:0042060]	cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	basolateral plasma membrane [GO:0016323]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; myelin sheath abaxonal region [GO:0035748]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Scrib-APC-beta-catenin complex [GO:0034750]; synapse [GO:0045202]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]	cadherin binding [GO:0045296]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1x5ra1_d2m0ta1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor signaling complex adaptor activity [GO:0030159]; artery smooth muscle contraction [GO:0014824]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; Notch signaling pathway [GO:0007219]; positive regulation of blood pressure [GO:0045777]; vesicle-mediated transport in synapse [GO:0099003]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]; beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	artery smooth muscle contraction [GO:0014824]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; Notch signaling pathway [GO:0007219]; positive regulation of blood pressure [GO:0045777]; vesicle-mediated transport in synapse [GO:0099003]	actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein-containing complex assembly [GO:0065003]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]	receptor signaling complex adaptor activity [GO:0030159]	beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]
d1x5xa1_d1iarb1__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; vesicle membrane [GO:0012506]; RNA binding [GO:0003723]; cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286]	centriolar satellite [GO:0034451]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; interleukin-4 receptor activity [GO:0004913]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; immune response [GO:0006955]; immunoglobulin mediated immune response [GO:0016064]; negative regulation of T-helper 1 cell differentiation [GO:0045626]; ovulation [GO:0030728]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; production of molecular mediator involved in inflammatory response [GO:0002532]; regulation of cell population proliferation [GO:0042127]; response to estrogen [GO:0043627]; response to odorant [GO:1990834]; signal transduction [GO:0007165]	cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286]	cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; immune response [GO:0006955]; immunoglobulin mediated immune response [GO:0016064]; negative regulation of T-helper 1 cell differentiation [GO:0045626]; ovulation [GO:0030728]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; production of molecular mediator involved in inflammatory response [GO:0002532]; regulation of cell population proliferation [GO:0042127]; response to estrogen [GO:0043627]; response to odorant [GO:1990834]; signal transduction [GO:0007165]	acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; vesicle membrane [GO:0012506]	centriolar satellite [GO:0034451]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	RNA binding [GO:0003723]	interleukin-4 receptor activity [GO:0004913]
d1x6ia1_d1puza___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein flavinylation [GO:0017013]; respiratory chain complex II assembly [GO:0034552]; succinate metabolic process [GO:0006105]		protein flavinylation [GO:0017013]; respiratory chain complex II assembly [GO:0034552]; succinate metabolic process [GO:0006105]		cytoplasm [GO:0005737]			
d1x6la1_d1cxea1__1			Proteobacteria	Firmicutes	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1x6na1_d2b6bb1__1		Metazoa	Proteobacteria	Chordata	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]
d1x6oa2_d3a74b1__1				Firmicutes	ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; translational frameshifting [GO:0006452]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; translational frameshifting [GO:0006452]	lysyl-tRNA aminoacylation [GO:0006430]		cytoplasm [GO:0005737]	ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d1x6va1_d1v47b1__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; sulfate assimilation [GO:0000103]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	sulfate assimilation [GO:0000103]	cytosol [GO:0005829]		adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1x6va2_d3iuba___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]; beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	cytosol [GO:0005829]	cytosol [GO:0005829]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]
d1x6vb1_d1i2dc1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1x6vb2_d1qjcb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	coenzyme A biosynthetic process [GO:0015937]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1x70a2_d1orwc2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d1x7ac__d3qzrb___1	Metazoa		Chordata		extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	cysteine-type endopeptidase activity [GO:0004197]	blood coagulation [GO:0007596]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]		extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]
d1x7na1_d2ixca___1			Euryarchaeota	Actinobacteria	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]	cytoplasm [GO:0005737]		glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d1x7qa1_d1r5vd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1x7qa2_d2j8ua2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1x7sb__d2h6ua___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1x7wb2_d1gpub3__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	pentose-phosphate shunt [GO:0006098]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d1x7wb2_d3exgb2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1x7yb1_d1powa3__1	Metazoa		Chordata	Firmicutes	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]		mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]		3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d1x7yb2_d3dvah2__1	Metazoa		Chordata	Firmicutes	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]		3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1x7zb2_d2g25a3__1	Metazoa		Chordata	Proteobacteria	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	cytosol [GO:0005829]; membrane [GO:0016020]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]
d1x80b1_d1zpdb2__1	Metazoa		Chordata	Proteobacteria	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]		mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]		3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1x83a1_d1hx3a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]
d1x83a1_d5anwa___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTP diphosphatase activity [GO:0036219]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]; aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTPase activity [GO:0003924]; GTP diphosphatase activity [GO:0036219]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]
d1x83b2_d1k2ea1__1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	hydrolase activity [GO:0016787]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]		cytoplasm [GO:0005737]		hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]	hydrolase activity [GO:0016787]
d1x86e1_d1lb1a1__1	Metazoa	Metazoa	Chordata	Chordata	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d1x86e1_d3odob1__1	Metazoa	Metazoa	Chordata	Chordata	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; RNA binding [GO:0003723]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]	G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; RNA binding [GO:0003723]
d1x89c__d1cbqa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d1x8ha1_d2zdfa___1			Proteobacteria		periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	
d1x8lb__d3avqa___1	Metazoa		Arthropoda	Actinobacteria	metal ion binding [GO:0046872]; sulfotransferase activity [GO:0008146]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]		coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; sulfotransferase activity [GO:0008146]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d1x8oa__d5urac1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cell periphery [GO:0071944]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; lipid binding [GO:0008289]; cell proliferation in forebrain [GO:0021846]; epithelial cell proliferation [GO:0050673]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]; triglyceride catabolic process [GO:0019433]	vasodilation [GO:0042311]	cell proliferation in forebrain [GO:0021846]; epithelial cell proliferation [GO:0050673]; negative regulation of cell population proliferation [GO:0008285]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	cell-cell junction [GO:0005911]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	lipid binding [GO:0008289]
d1x8pa__d4i3ba___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cytoplasm [GO:0005737]; lipid binding [GO:0008289]; bioluminescence [GO:0008218]	vasodilation [GO:0042311]	bioluminescence [GO:0008218]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	lipid binding [GO:0008289]
d1x8qa__d1s2pb___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	extracellular space [GO:0005615]; pigment binding [GO:0031409]	vasodilation [GO:0042311]		extracellular region [GO:0005576]	extracellular space [GO:0005615]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	pigment binding [GO:0031409]
d1x8ta__d3slhb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; 3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]	3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]
d1x8uc__d5d47a1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1x8za1_d1xg2b1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	apoplast [GO:0048046]; pollen tube tip [GO:0090404]; pectinesterase activity [GO:0030599]; pectinesterase inhibitor activity [GO:0046910]; pollen tube growth [GO:0009860]	cytoplasm [GO:0005737]; pectinesterase inhibitor activity [GO:0046910]	pollen tube growth [GO:0009860]		apoplast [GO:0048046]; pollen tube tip [GO:0090404]	cytoplasm [GO:0005737]	pectinesterase activity [GO:0030599]; pectinesterase inhibitor activity [GO:0046910]	pectinesterase inhibitor activity [GO:0046910]
d1x8zb__d2cj4a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	apoplast [GO:0048046]; pollen tube tip [GO:0090404]; pectinesterase activity [GO:0030599]; pectinesterase inhibitor activity [GO:0046910]; pollen tube growth [GO:0009860]	enzyme inhibitor activity [GO:0004857]; negative regulation of catalytic activity [GO:0043086]	pollen tube growth [GO:0009860]	negative regulation of catalytic activity [GO:0043086]	apoplast [GO:0048046]; pollen tube tip [GO:0090404]		pectinesterase activity [GO:0030599]; pectinesterase inhibitor activity [GO:0046910]	enzyme inhibitor activity [GO:0004857]
d1x91a__d2xqrl___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	apoplast [GO:0048046]; pollen tube tip [GO:0090404]; pectinesterase activity [GO:0030599]; pectinesterase inhibitor activity [GO:0046910]; pollen tube growth [GO:0009860]	apoplast [GO:0048046]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]; defense response to fungus [GO:0050832]; response to karrikin [GO:0080167]; response to wounding [GO:0009611]	pollen tube growth [GO:0009860]	carbohydrate metabolic process [GO:0005975]; defense response to fungus [GO:0050832]; response to karrikin [GO:0080167]; response to wounding [GO:0009611]	apoplast [GO:0048046]; pollen tube tip [GO:0090404]	apoplast [GO:0048046]; cell wall [GO:0005618]; plasma membrane [GO:0005886]	pectinesterase activity [GO:0030599]; pectinesterase inhibitor activity [GO:0046910]	beta-fructofuranosidase activity [GO:0004564]
d1x96a__d1s2aa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]; 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; prostaglandin-F synthase activity [GO:0047017]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin-F synthase activity [GO:0047017]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]
d1x97a__d1az2a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d1x9ab__d2d1pe___1			Thermotogae	Proteobacteria	sulfurtransferase complex [GO:1990228]; tRNA wobble position uridine thiolation [GO:0002143]	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]; sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	sulfurtransferase complex [GO:1990228]	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]		sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]
d1x9ea2_d1m1mb1__1			Firmicutes	Actinobacteria	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		cytoplasm [GO:0005737]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d1x9fa__d2hz1a___1	Metazoa		Annelida	Cyanobacteria	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	cell [GO:0005623]; cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1x9fc__d3uhka___1	Metazoa	Metazoa	Annelida	Mollusca	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1x9ff__d1hlma___1	Metazoa	Metazoa	Annelida	Echinodermata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1x9fg__d5nb3a___1	Metazoa		Annelida	Cyanobacteria	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1x9fi__d3hxna___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1x9fl__d4po5c1__1	Metazoa		Annelida	Cyanobacteria	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1x9ib__d1vimb1__1			Crenarchaeota	Euryarchaeota	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]; carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	carbohydrate derivative binding [GO:0097367]; isomerase activity [GO:0016853]; carbohydrate derivative metabolic process [GO:1901135]	carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	carbohydrate derivative metabolic process [GO:1901135]			carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]	carbohydrate derivative binding [GO:0097367]; isomerase activity [GO:0016853]
d1x9ja1_d3wxld2__1			Thermotogae		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]		carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d1x9jd1_d3h1vx1__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]		calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]
d1x9jf1_d2bupa1__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]		axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d1x9jg2_d1dgaa4__1			Thermotogae		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]				cytoplasm [GO:0005737]		ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	
d1x9jh1_d3hm8c1__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]		canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]
d1x9na2_d2pqac___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA ligase (ATP) activity [GO:0003910]; DNA ligase activity [GO:0003909]; metal ion binding [GO:0046872]; anatomical structure morphogenesis [GO:0009653]; base-excision repair [GO:0006284]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; lagging strand elongation [GO:0006273]; mismatch repair [GO:0006298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; Okazaki fragment processing involved in mitotic DNA replication [GO:1903461]; transcription-coupled nucleotide-excision repair [GO:0006283]	DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; single-stranded DNA binding [GO:0003697]; base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	anatomical structure morphogenesis [GO:0009653]; base-excision repair [GO:0006284]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; lagging strand elongation [GO:0006273]; mismatch repair [GO:0006298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; Okazaki fragment processing involved in mitotic DNA replication [GO:1903461]; transcription-coupled nucleotide-excision repair [GO:0006283]	base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA ligase (ATP) activity [GO:0003910]; DNA ligase activity [GO:0003909]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; single-stranded DNA binding [GO:0003697]
d1x9ya1_d3lxsc___1			Firmicutes		extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]; pathogenesis [GO:0009405]	cysteine-type endopeptidase activity [GO:0004197]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]		cysteine-type peptidase activity [GO:0008234]	cysteine-type endopeptidase activity [GO:0004197]
d1x9yb1_d2avwa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]; pathogenesis [GO:0009405]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]		cysteine-type peptidase activity [GO:0008234]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]
d1x9yb1_d2prea___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]; pathogenesis [GO:0009405]	cysteine-type peptidase activity [GO:0008234]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]		cysteine-type peptidase activity [GO:0008234]	cysteine-type peptidase activity [GO:0008234]
d1x9yb2_d3ksef___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]; pathogenesis [GO:0009405]	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	pathogenesis [GO:0009405]	cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	extracellular region [GO:0005576]	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	cysteine-type peptidase activity [GO:0008234]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]
d1xaca__d4zdaa___1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]		3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]
d1xana3_d1dxla3__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; glycine cleavage complex [GO:0005960]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]; glycine cleavage complex [GO:0005960]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]	dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]
d1xaqa1_d4hs5b___1				Proteobacteria		ferric iron binding [GO:0008199]; iron-sulfur cluster assembly [GO:0016226]		iron-sulfur cluster assembly [GO:0016226]				ferric iron binding [GO:0008199]
d1xara__d1uosc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; calcium-dependent protein binding [GO:0048306]; carbohydrate binding [GO:0030246]; ICAM-3 receptor activity [GO:0030369]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; signaling receptor activity [GO:0038023]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]	extracellular region [GO:0005576]	calcium-dependent protein binding [GO:0048306]; carbohydrate binding [GO:0030246]; ICAM-3 receptor activity [GO:0030369]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; signaling receptor activity [GO:0038023]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]	toxin activity [GO:0090729]
d1xara__d4pz4a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; calcium-dependent protein binding [GO:0048306]; carbohydrate binding [GO:0030246]; ICAM-3 receptor activity [GO:0030369]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; signaling receptor activity [GO:0038023]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; collagen binding [GO:0005518]; hyaluronic acid binding [GO:0005540]; transmembrane signaling receptor activity [GO:0004888]; cartilage development [GO:0051216]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cellular response to fibroblast growth factor stimulus [GO:0044344]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte migration [GO:0050900]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; wound healing, spreading of cells [GO:0044319]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	cartilage development [GO:0051216]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte migration [GO:0050900]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	calcium-dependent protein binding [GO:0048306]; carbohydrate binding [GO:0030246]; ICAM-3 receptor activity [GO:0030369]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; signaling receptor activity [GO:0038023]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]	collagen binding [GO:0005518]; hyaluronic acid binding [GO:0005540]; transmembrane signaling receptor activity [GO:0004888]
d1xata__d3ou9a___1			Proteobacteria	Euryarchaeota	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	response to antibiotic [GO:0046677]				chloramphenicol O-acetyltransferase activity [GO:0008811]	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]
d1xb3b__d1ilsd___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d1xb6b__d1zdsb2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1xb8c__d2fqfa2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d1xbpe1_d1yjne1__1			Deinococcus-Thermus	Euryarchaeota	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1xbpi1_d2qozk1__1			Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	
d1xbps1_d3df2u1__1			Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	
d1xbvb__d3ltsa___1			Proteobacteria	Euryarchaeota	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1xbxb__d2nv2w___1			Proteobacteria	Firmicutes	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]; glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]		cytosol [GO:0005829]; glutaminase complex [GO:1903600]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]	glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d1xbyb__d1tjpa___1			Proteobacteria	Proteobacteria	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]
d1xc1f__d2xxka1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]	
d1xc1i__d3seva1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1xc1i__d4lz8c___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1xc3a1_d1xupo2__1			Firmicutes	Firmicutes	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]; negative regulation of transcription, DNA-templated [GO:0045892]; polysaccharide catabolic process [GO:0000272]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	negative regulation of transcription, DNA-templated [GO:0045892]; polysaccharide catabolic process [GO:0000272]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]			ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d1xc3a1_d3bp8b2__1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]; negative regulation of transcription, DNA-templated [GO:0045892]; polysaccharide catabolic process [GO:0000272]	cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; glucose transmembrane transporter activity [GO:0005355]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; protein-phosphocysteine-glucose phosphotransferase system transporter activity [GO:0090564]; glucose transmembrane transport [GO:1904659]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	negative regulation of transcription, DNA-templated [GO:0045892]; polysaccharide catabolic process [GO:0000272]	glucose transmembrane transport [GO:1904659]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]		cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]	glucose transmembrane transporter activity [GO:0005355]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; protein-phosphocysteine-glucose phosphotransferase system transporter activity [GO:0090564]
d1xc3a2_d3fzfa2__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]; negative regulation of transcription, DNA-templated [GO:0045892]; polysaccharide catabolic process [GO:0000272]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	negative regulation of transcription, DNA-templated [GO:0045892]; polysaccharide catabolic process [GO:0000272]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d1xc6a2_d2xhna3__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; extracellular space [GO:0005615]; beta-galactosidase activity [GO:0004565]; galactose binding [GO:0005534]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	beta-galactosidase activity [GO:0004565]; galactose binding [GO:0005534]	carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]
d1xc6a3_d2wbka1__1	Fungi		Ascomycota	Bacteroidetes	extracellular region [GO:0005576]; extracellular space [GO:0005615]; beta-galactosidase activity [GO:0004565]; galactose binding [GO:0005534]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]; extracellular space [GO:0005615]		beta-galactosidase activity [GO:0004565]; galactose binding [GO:0005534]	beta-mannosidase activity [GO:0004567]
d1xcaa__d1i06a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]
d1xcbe1_d3pqjc___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]	negative regulation of transcription, DNA-templated [GO:0045892]	cytoplasm [GO:0005737]	protein-DNA complex [GO:0032993]	coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]	DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1xccd__d3tkqd___1		Metazoa	Apicomplexa	Chordata	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	peroxiredoxin activity [GO:0051920]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d1xcga1_d1x86a1__1	Metazoa	Metazoa	Chordata	Chordata	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d1xcha__d2qrwe___1	Metazoa		Chordata	Actinobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1xcka3_d1q3qd2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1xcke3_d1q3qc2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1xckf3_d3osxa1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein refolding [GO:0042026]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	protein refolding [GO:0042026]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1xcla__d3lhdc___1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]	tRNA (m1A) methyltransferase complex [GO:0031515]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]	creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	tRNA (m1A) methyltransferase complex [GO:0031515]	guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]
d1xcob1_d2af3c___1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	plasma membrane [GO:0005886]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	acetyl-CoA biosynthetic process [GO:0006085]	acetyl-CoA biosynthetic process [GO:0006085]	cytoplasm [GO:0005737]	plasma membrane [GO:0005886]	phosphate acetyltransferase activity [GO:0008959]	phosphate acetyltransferase activity [GO:0008959]
d1xcod1_d4iwhb___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	acetyl-CoA biosynthetic process [GO:0006085]	leucine biosynthetic process [GO:0009098]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	phosphate acetyltransferase activity [GO:0008959]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1xcof__d5hn5a___1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	mitochondrion [GO:0005739]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; homoisocitrate dehydrogenase activity [GO:0047046]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]; lysine biosynthetic process [GO:0009085]	acetyl-CoA biosynthetic process [GO:0006085]	leucine biosynthetic process [GO:0009098]; lysine biosynthetic process [GO:0009085]	cytoplasm [GO:0005737]	mitochondrion [GO:0005739]	phosphate acetyltransferase activity [GO:0008959]	3-isopropylmalate dehydrogenase activity [GO:0003862]; homoisocitrate dehydrogenase activity [GO:0047046]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1xcpb1_d1ny6g___1			Proteobacteria	Aquificae	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d1xcxa1_d5n7ja2__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	amylosucrase activity [GO:0047669]
d1xd0a2_d1x38a1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1xd1a2_d1piga2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate catabolic process [GO:0016052]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular space [GO:0005615]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1xd3a__d5ja7a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d1xd4a3_d1gg3b2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleosome [GO:0000786]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; DNA binding [GO:0003677]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein heterodimerization activity [GO:0046982]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; SH3 domain binding [GO:0017124]; axon guidance [GO:0007411]; B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; vitellogenesis [GO:0007296]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	axon guidance [GO:0007411]; B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; vitellogenesis [GO:0007296]	actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleosome [GO:0000786]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	DNA binding [GO:0003677]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein heterodimerization activity [GO:0046982]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; SH3 domain binding [GO:0017124]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]
d1xd5a__d5d5gc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d1xd5b__d5t20p___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta								
d1xd5c__d2d04h___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta		carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]
d1xd5d__d4tkca___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota		carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]
d1xd9a__d5de3a1__1		Viridiplantae	Proteobacteria	Chlorophyta	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	Golgi membrane [GO:0000139]; nucleus [GO:0005634]; spindle [GO:0005819]; GTP binding [GO:0005525]; cell cycle [GO:0007049]; cell division [GO:0051301]; protein transport [GO:0015031]	nitrogen fixation [GO:0009399]	cell cycle [GO:0007049]; cell division [GO:0051301]; protein transport [GO:0015031]	molybdenum-iron nitrogenase complex [GO:0016612]	Golgi membrane [GO:0000139]; nucleus [GO:0005634]; spindle [GO:0005819]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	GTP binding [GO:0005525]
d1xd9b__d1gzsc___1		Metazoa	Proteobacteria	Chordata	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	nitrogen fixation [GO:0009399]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	molybdenum-iron nitrogenase complex [GO:0016612]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]
d1xdfa1_d1z02e2__1	Viridiplantae		Streptophyta	Proteobacteria	cytosol [GO:0005829]; abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]		cytosol [GO:0005829]		abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d1xdfb__d2de5a2__1	Viridiplantae		Streptophyta	Proteobacteria	cytosol [GO:0005829]; abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]	carbazole catabolic process [GO:0046232]	cytosol [GO:0005829]		abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]
d1xdoa2_d2ozxa___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; periplasmic side of cell outer membrane [GO:0031241]; plasma membrane [GO:0005886]; polyphosphate kinase complex [GO:0009358]; ATP binding [GO:0005524]; diphosphotransferase activity [GO:0016778]; metal ion binding [GO:0046872]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; polyphosphate kinase activity [GO:0008976]; polyphosphate:AMP phosphotransferase activity [GO:0043751]; ATP generation from ADP [GO:0006757]; polyphosphate biosynthetic process [GO:0006799]; protein autophosphorylation [GO:0046777]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; calcium channel inhibitor activity [GO:0019855]; ion channel binding [GO:0044325]; protein histidine phosphatase activity [GO:0101006]; negative regulation of ATP citrate synthase activity [GO:2000984]; negative regulation of lyase activity [GO:0051350]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-histidine dephosphorylation [GO:0035971]; positive regulation of cell motility [GO:2000147]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein dephosphorylation [GO:0006470]; regulation of actin cytoskeleton reorganization [GO:2000249]	ATP generation from ADP [GO:0006757]; polyphosphate biosynthetic process [GO:0006799]; protein autophosphorylation [GO:0046777]	negative regulation of ATP citrate synthase activity [GO:2000984]; negative regulation of lyase activity [GO:0051350]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-histidine dephosphorylation [GO:0035971]; positive regulation of cell motility [GO:2000147]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein dephosphorylation [GO:0006470]; regulation of actin cytoskeleton reorganization [GO:2000249]	cytosol [GO:0005829]; periplasmic side of cell outer membrane [GO:0031241]; plasma membrane [GO:0005886]; polyphosphate kinase complex [GO:0009358]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; diphosphotransferase activity [GO:0016778]; metal ion binding [GO:0046872]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; polyphosphate:AMP phosphotransferase activity [GO:0043751]; polyphosphate kinase activity [GO:0008976]	calcium channel inhibitor activity [GO:0019855]; ion channel binding [GO:0044325]; protein histidine phosphatase activity [GO:0101006]
d1xdob3_d1rfia1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; periplasmic side of cell outer membrane [GO:0031241]; plasma membrane [GO:0005886]; polyphosphate kinase complex [GO:0009358]; ATP binding [GO:0005524]; diphosphotransferase activity [GO:0016778]; metal ion binding [GO:0046872]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; polyphosphate kinase activity [GO:0008976]; polyphosphate:AMP phosphotransferase activity [GO:0043751]; ATP generation from ADP [GO:0006757]; polyphosphate biosynthetic process [GO:0006799]; protein autophosphorylation [GO:0046777]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 3'-tyrosyl-DNA phosphodiesterase activity [GO:0017005]; double-stranded DNA binding [GO:0003690]; exonuclease activity [GO:0004527]; single-stranded DNA binding [GO:0003697]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012]	ATP generation from ADP [GO:0006757]; polyphosphate biosynthetic process [GO:0006799]; protein autophosphorylation [GO:0046777]	DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012]	cytosol [GO:0005829]; periplasmic side of cell outer membrane [GO:0031241]; plasma membrane [GO:0005886]; polyphosphate kinase complex [GO:0009358]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; diphosphotransferase activity [GO:0016778]; metal ion binding [GO:0046872]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; polyphosphate:AMP phosphotransferase activity [GO:0043751]; polyphosphate kinase activity [GO:0008976]	3'-tyrosyl-DNA phosphodiesterase activity [GO:0017005]; double-stranded DNA binding [GO:0003690]; exonuclease activity [GO:0004527]; single-stranded DNA binding [GO:0003697]
d1xdva1_d3t06a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleosome [GO:0000786]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; DNA binding [GO:0003677]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein heterodimerization activity [GO:0046982]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; SH3 domain binding [GO:0017124]; axon guidance [GO:0007411]; B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; vitellogenesis [GO:0007296]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	axon guidance [GO:0007411]; B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; vitellogenesis [GO:0007296]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleosome [GO:0000786]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	DNA binding [GO:0003677]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein heterodimerization activity [GO:0046982]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; SH3 domain binding [GO:0017124]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d1xe3e__d1y6rb___1			Firmicutes	Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	cytosol [GO:0005829]; adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]	purine nucleoside metabolic process [GO:0042278]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]		cytosol [GO:0005829]	purine-nucleoside phosphorylase activity [GO:0004731]	adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]
d1xe4a2_d4c68c1__1			Firmicutes	Apicomplexa	UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity [GO:0047206]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	N-terminal protein myristoylation [GO:0006499]			UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity [GO:0047206]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d1xe5b__d5p7qa___1		Fungi	Apicomplexa	Ascomycota	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]			vacuole [GO:0005773]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1xe6a__d5p28a___1		Fungi	Apicomplexa	Ascomycota	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]			vacuole [GO:0005773]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1xe6b__d5is4a___1		Fungi	Apicomplexa	Ascomycota	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]			vacuole [GO:0005773]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d1xeda1_d2zkhl1__1	Metazoa		Chordata		azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; polymeric immunoglobulin receptor activity [GO:0001792]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc receptor signaling pathway [GO:0038093]; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [GO:0002415]; neutrophil degranulation [GO:0043312]; receptor clustering [GO:0043113]; retina homeostasis [GO:0001895]		detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc receptor signaling pathway [GO:0038093]; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [GO:0002415]; neutrophil degranulation [GO:0043312]; receptor clustering [GO:0043113]; retina homeostasis [GO:0001895]		azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		polymeric immunoglobulin receptor activity [GO:0001792]	
d1xedf1_d4kvcl1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; polymeric immunoglobulin receptor activity [GO:0001792]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc receptor signaling pathway [GO:0038093]; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [GO:0002415]; neutrophil degranulation [GO:0043312]; receptor clustering [GO:0043113]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc receptor signaling pathway [GO:0038093]; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [GO:0002415]; neutrophil degranulation [GO:0043312]; receptor clustering [GO:0043113]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	polymeric immunoglobulin receptor activity [GO:0001792]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1xeja__d1l50a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1xeja__d2heda___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1xeqa1_d3m8ak___1			Negarnaviricota	Negarnaviricota	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; RNA binding [GO:0003723]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; RNA binding [GO:0003723]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d1xeqb__d2zkoa___1			Negarnaviricota	Negarnaviricota	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; RNA binding [GO:0003723]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	cytosol [GO:0005829]; host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; evasion or tolerance by virus of host immune response [GO:0030683]; modification by virus of host mRNA processing [GO:0046778]; modulation by virus of host cellular process [GO:0019054]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	evasion or tolerance by virus of host immune response [GO:0030683]; modification by virus of host mRNA processing [GO:0046778]; modulation by virus of host cellular process [GO:0019054]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	cytosol [GO:0005829]; host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; nucleoplasm [GO:0005654]	RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d1xesa1_d4c71b2__1	Viridiplantae		Streptophyta		cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]		biosynthetic process [GO:0009058]		cytoplasm [GO:0005737]		pinosylvin synthase activity [GO:0050198]	
d1xesb1_d2vb9a2__1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	pinosylvin synthase activity [GO:0050198]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1xesb2_d4o99c1__1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	biosynthetic process [GO:0009058]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	pinosylvin synthase activity [GO:0050198]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1xeta1_d2aq7d1__1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	pinosylvin synthase activity [GO:0050198]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1xeta2_d1ou6c2__1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	biosynthetic process [GO:0009058]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	pinosylvin synthase activity [GO:0050198]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1xeta2_d4v2pb2__1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		pinosylvin synthase activity [GO:0050198]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1xetb1_d4o99d2__1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	biosynthetic process [GO:0009058]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	pinosylvin synthase activity [GO:0050198]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1xeua1_d2wquc1__1			Firmicutes	Firmicutes		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		heparin binding [GO:0008201]; lipid binding [GO:0008289]
d1xevb__d4cnwa___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1xf2a1_d1j5oh1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1xf2l1_d3wjja2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1xf3a2_d6b0gc1__1	Metazoa		Chordata	Apicomplexa	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; plasma membrane [GO:0005886]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1xf4a2_d1zwia1__1	Metazoa		Chordata	Actinobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	voltage-gated potassium channel complex [GO:0008076]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1xf4a2_d3fctb2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1xf4l1_d4od3l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1xf4l2_d4p5mg2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d1xfba1_d5e2la___1	Metazoa		Chordata	Actinobacteria	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]; canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; manganese ion binding [GO:0030145]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; protein homooligomerization [GO:0051260]	canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; protein homooligomerization [GO:0051260]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; manganese ion binding [GO:0030145]
d1xfbd__d3lbmc___1	Metazoa		Chordata	Proteobacteria	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]; canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]	cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d1xfbd__d5u4na___1	Metazoa		Chordata	Proteobacteria	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]; canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	fructose-bisphosphate aldolase activity [GO:0004332]; zinc ion binding [GO:0008270]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	glycolytic process [GO:0006096]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]		cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]	fructose-bisphosphate aldolase activity [GO:0004332]; zinc ion binding [GO:0008270]
d1xfbf__d4guia___1	Metazoa		Chordata	Proteobacteria	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]; canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]		cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]	3-dehydroquinate dehydratase activity [GO:0003855]
d1xfbf__d4iuob1__1	Metazoa		Chordata	Proteobacteria	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]; canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]		cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]	3-dehydroquinate dehydratase activity [GO:0003855]
d1xfbh__d1qo5e___1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]; canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose binding [GO:0070061]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]; canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]	cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]	ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose binding [GO:0070061]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]
d1xfbi__d1vlwb1__1	Metazoa		Chordata	Thermotogae	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]; canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	lyase activity [GO:0016829]	canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]		cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]	lyase activity [GO:0016829]
d1xfbj__d5c54f___1	Metazoa		Chordata	Actinobacteria	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]; canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; N-acetylneuraminate lyase activity [GO:0008747]	canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]		cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; N-acetylneuraminate lyase activity [GO:0008747]
d1xfbk__d1xxxb___1	Metazoa		Chordata	Actinobacteria	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]; canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d1xfda1_d3q0ta1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]; potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1xfdb1_d2oqid1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]; potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1xfdc2_d1a88a___1	Metazoa		Chordata	Actinobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]; potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	chloride peroxidase activity [GO:0016691]	protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]		potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]	chloride peroxidase activity [GO:0016691]
d1xfdd2_d5gmab1__1	Metazoa		Chordata	Thermotogae	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]; potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]	protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]	cytoplasm [GO:0005737]	potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]	acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]
d1xffa__d3tddm___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1xfga__d1te5b___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]		carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]		cytosol [GO:0005829]		carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	
d1xfka__d1pq3a___1		Metazoa	Proteobacteria	Chordata	agmatinase activity [GO:0008783]; formimidoylglutamase activity [GO:0050415]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [GO:0016813]; manganese ion binding [GO:0030145]; histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	agmatinase activity [GO:0008783]; formimidoylglutamase activity [GO:0050415]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [GO:0016813]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d1xfla__d4mjaa___1	Viridiplantae		Streptophyta	Cyanobacteria	cell [GO:0005623]; cytosol [GO:0005829]; enzyme activator activity [GO:0008047]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; positive regulation of catalytic activity [GO:0043085]	cell [GO:0005623]; electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; positive regulation of catalytic activity [GO:0043085]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]	enzyme activator activity [GO:0008047]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]	electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]
d1xfna__d5vika1__1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	
d1xfpl__d1l00a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1xfqa__d4i3ja___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d1xfqa__d5kiza1__1		Metazoa	Proteobacteria	Chordata	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]		cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d1xfup1_d2ki4b___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1xfuq1_d1dflx___1	Metazoa	Metazoa	Chordata	Mollusca	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]
d1xfuq1_d1djxb1__1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]
d1xfus1_d1mxea___1	Metazoa	Metazoa	Chordata	Arthropoda	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell [GO:0005623]; cell cortex [GO:0005938]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; myosin V complex [GO:0031475]; myosin VI complex [GO:0031476]; nucleoplasm [GO:0005654]; rhabdomere [GO:0016028]; spindle [GO:0005819]; calcium ion binding [GO:0005509]; myosin heavy chain binding [GO:0032036]; myosin V binding [GO:0031489]; myosin VI head/neck binding [GO:0070855]; actin filament-based movement [GO:0030048]; adaptation of rhodopsin mediated signaling [GO:0016062]; calcium-mediated signaling [GO:0019722]; cellular response to ethanol [GO:0071361]; centriole replication [GO:0007099]; deactivation of rhodopsin mediated signaling [GO:0016059]; kinetochore organization [GO:0051383]; metarhodopsin inactivation [GO:0016060]; muscle cell cellular homeostasis [GO:0046716]; photoreceptor cell axon guidance [GO:0072499]; positive regulation of cation channel activity [GO:2001259]; protein phosphorylation [GO:0006468]; regulation of light-activated channel activity [GO:0016061]; rhabdomere development [GO:0042052]; rhodopsin mediated signaling pathway [GO:0016056]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	actin filament-based movement [GO:0030048]; adaptation of rhodopsin mediated signaling [GO:0016062]; calcium-mediated signaling [GO:0019722]; cellular response to ethanol [GO:0071361]; centriole replication [GO:0007099]; deactivation of rhodopsin mediated signaling [GO:0016059]; kinetochore organization [GO:0051383]; metarhodopsin inactivation [GO:0016060]; muscle cell cellular homeostasis [GO:0046716]; photoreceptor cell axon guidance [GO:0072499]; positive regulation of cation channel activity [GO:2001259]; protein phosphorylation [GO:0006468]; regulation of light-activated channel activity [GO:0016061]; rhabdomere development [GO:0042052]; rhodopsin mediated signaling pathway [GO:0016056]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cell [GO:0005623]; cell cortex [GO:0005938]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; myosin V complex [GO:0031475]; myosin VI complex [GO:0031476]; nucleoplasm [GO:0005654]; rhabdomere [GO:0016028]; spindle [GO:0005819]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]; myosin heavy chain binding [GO:0032036]; myosin V binding [GO:0031489]; myosin VI head/neck binding [GO:0070855]
d1xfut1_d3iqqa___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1xfvp1_d3ko0s___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d1xfvq1_d3ko0a___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d1xfvs1_d1n2da___1	Metazoa	Fungi	Chordata	Ascomycota	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; MIH complex [GO:0120155]; myosin II complex [GO:0016460]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; myosin II heavy chain binding [GO:0032038]; myosin V binding [GO:0031489]; actomyosin contractile ring assembly [GO:0000915]; protein localization [GO:0008104]; vesicle targeting [GO:0006903]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	actomyosin contractile ring assembly [GO:0000915]; protein localization [GO:0008104]; vesicle targeting [GO:0006903]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; MIH complex [GO:0120155]; myosin II complex [GO:0016460]; vesicle [GO:0031982]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; myosin II heavy chain binding [GO:0032038]; myosin V binding [GO:0031489]
d1xfvt1_d3ts5c___1	Metazoa	Metazoa	Chordata	Mollusca	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	myosin complex [GO:0016459]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	myosin complex [GO:0016459]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]
d1xfwo1_d3c1vd___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d1xfwo1_d4hexa___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]
d1xfws1_d1boda___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]
d1xfyr1_d2zrsd___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]
d1xfys1_d2lcpa___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	calyx of Held [GO:0044305]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dense core granule [GO:0031045]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic cytosol [GO:0099523]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; protein kinase binding [GO:0019901]; voltage-gated calcium channel activity [GO:0005245]; voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels [GO:0099626]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of exocytosis [GO:0045921]; regulation of neuron projection development [GO:0010975]; regulation of synaptic vesicle exocytosis [GO:2000300]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of exocytosis [GO:0045921]; regulation of neuron projection development [GO:0010975]; regulation of synaptic vesicle exocytosis [GO:2000300]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calyx of Held [GO:0044305]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dense core granule [GO:0031045]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic cytosol [GO:0099523]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; protein kinase binding [GO:0019901]; voltage-gated calcium channel activity [GO:0005245]; voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels [GO:0099626]
d1xfzq1_d1psbb___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1xfzr1_d4ndcb___1	Metazoa	Metazoa	Chordata	Mollusca	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	metal ion binding [GO:0046872]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]		adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	metal ion binding [GO:0046872]
d1xfzt1_d3lk0d___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d1xg3a__d4mf4b___1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; methylisocitrate lyase activity [GO:0046421]; propionate catabolic process, 2-methylcitrate cycle [GO:0019629]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	propionate catabolic process, 2-methylcitrate cycle [GO:0019629]				magnesium ion binding [GO:0000287]; methylisocitrate lyase activity [GO:0046421]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]
d1xg3b__d5e9ha___1		Fungi	Proteobacteria	Ascomycota	magnesium ion binding [GO:0000287]; methylisocitrate lyase activity [GO:0046421]; propionate catabolic process, 2-methylcitrate cycle [GO:0019629]	glyoxysome [GO:0009514]; isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	propionate catabolic process, 2-methylcitrate cycle [GO:0019629]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]		glyoxysome [GO:0009514]	magnesium ion binding [GO:0000287]; methylisocitrate lyase activity [GO:0046421]	isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]
d1xg3c__d1izca___1		Fungi	Proteobacteria	Ascomycota	magnesium ion binding [GO:0000287]; methylisocitrate lyase activity [GO:0046421]; propionate catabolic process, 2-methylcitrate cycle [GO:0019629]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	propionate catabolic process, 2-methylcitrate cycle [GO:0019629]				magnesium ion binding [GO:0000287]; methylisocitrate lyase activity [GO:0046421]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1xg5c1_d2hmwb___1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 3-keto sterol reductase activity [GO:0000253]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; nucleotide binding [GO:0000166]; estrogen biosynthetic process [GO:0006703]; steroid biosynthetic process [GO:0006694]	plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; potassium ion transport [GO:0006813]	estrogen biosynthetic process [GO:0006703]; steroid biosynthetic process [GO:0006694]	potassium ion transport [GO:0006813]	extracellular region [GO:0005576]	plasma membrane [GO:0005886]	17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 3-keto sterol reductase activity [GO:0000253]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; nucleotide binding [GO:0000166]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]
d1xg5c1_d4ixwa___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 3-keto sterol reductase activity [GO:0000253]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; nucleotide binding [GO:0000166]; estrogen biosynthetic process [GO:0006703]; steroid biosynthetic process [GO:0006694]		estrogen biosynthetic process [GO:0006703]; steroid biosynthetic process [GO:0006694]		extracellular region [GO:0005576]		17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 3-keto sterol reductase activity [GO:0000253]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; nucleotide binding [GO:0000166]	
d1xg7a1_d4aiab___1			Euryarchaeota		class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; oxidized base lesion DNA N-glycosylase activity [GO:0000702]; base-excision repair [GO:0006284]		base-excision repair [GO:0006284]				class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; oxidized base lesion DNA N-glycosylase activity [GO:0000702]	
d1xg7b__d4ai5d1__1			Euryarchaeota		class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; oxidized base lesion DNA N-glycosylase activity [GO:0000702]; base-excision repair [GO:0006284]		base-excision repair [GO:0006284]				class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; oxidized base lesion DNA N-glycosylase activity [GO:0000702]	
d1xgma1_d1yw7a1__1		Metazoa	Euryarchaeota	Chordata	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; metalloexopeptidase activity [GO:0008235]; RNA binding [GO:0003723]; N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; protein initiator methionine removal [GO:0070084]; protein processing [GO:0016485]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	protein initiator methionine removal [GO:0070084]	N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; protein initiator methionine removal [GO:0070084]; protein processing [GO:0016485]; regulation of rhodopsin mediated signaling pathway [GO:0022400]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; metalloexopeptidase activity [GO:0008235]; RNA binding [GO:0003723]
d1xgmb1_d2oaza1__1		Metazoa	Euryarchaeota	Chordata	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; metalloexopeptidase activity [GO:0008235]; RNA binding [GO:0003723]; N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; protein initiator methionine removal [GO:0070084]; protein processing [GO:0016485]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	protein initiator methionine removal [GO:0070084]	N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; protein initiator methionine removal [GO:0070084]; protein processing [GO:0016485]; regulation of rhodopsin mediated signaling pathway [GO:0022400]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; metalloexopeptidase activity [GO:0008235]; RNA binding [GO:0003723]
d1xgra1_d1nd0h2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	metal ion binding [GO:0046872]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	metal ion binding [GO:0046872]
d1xgra2_d3we6b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	metal ion binding [GO:0046872]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	metal ion binding [GO:0046872]
d1xgva__d1osic___1			Crenarchaeota	Deinococcus-Thermus	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]		cytoplasm [GO:0005737]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1xgza1_d3s5zb2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d1xgza2_d1mxda2__1	Metazoa		Chordata	Euryarchaeota	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1xh0a2_d1v03a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1xhxb1_d2dtua1__1					DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]			DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1xhxb1_d4lsna2__1					DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1xhzb1_d1t05a1__1					DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1xhzd1_d4opjc___1				Firmicutes	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]			cytoplasm [GO:0005737]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d1xi0a__d1y2xd___1	Fungi	Fungi	Basidiomycota	Basidiomycota		carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]
d1xi1a1_d4jk9b___1		Metazoa		Chordata	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	catalytic step 2 spliceosome [GO:0071013]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal tri-snRNP complex assembly [GO:0000244]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal tri-snRNP complex assembly [GO:0000244]		catalytic step 2 spliceosome [GO:0071013]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]	K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]
d1xiba__d5nh4c___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d1xica__d2nq9a___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	D-xylose metabolic process [GO:0042732]	base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]
d1xica__d2xima___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xida__d5nhcc___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d1xiea__d5xind___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xifa__d4hhla___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xiga__d2gyib___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xiga__d5nh7c___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d1xiia__d1de5d___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; L-rhamnose isomerase activity [GO:0008740]; manganese ion binding [GO:0030145]; rhamnose binding [GO:0033296]; zinc ion binding [GO:0008270]; L-lyxose metabolic process [GO:0019324]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]	D-xylose metabolic process [GO:0042732]	L-lyxose metabolic process [GO:0019324]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	identical protein binding [GO:0042802]; L-rhamnose isomerase activity [GO:0008740]; manganese ion binding [GO:0030145]; rhamnose binding [GO:0033296]; zinc ion binding [GO:0008270]
d1xija__d5ximb___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xinb__d1xyaa___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xinc__d3kbsa___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xinc__d5nh8d___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d1xiva2_d4wlea2__1		Metazoa	Apicomplexa	Chordata	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d1xiva2_d5kvva2__1			Apicomplexa	Actinobacteria	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]
d1xiwa__d1d5ba1__1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1xiwc__d1pg7y1__1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1xiwc__d4kk8c2__1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1xiwe__d1f3dk1__1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	metal ion binding [GO:0046872]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]	metal ion binding [GO:0046872]
d1xiwe__d4cl7b___1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]
d1xiwg__d1r24d1__1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1xiwg__d4jn2a1__1	Metazoa		Chordata		alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]	
d1xiwh__d1de4g1__1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1xj4b__d1ew0a___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; nitrogen fixation [GO:0009399]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]
d1xjad__d2aacb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; arabinose catabolic process [GO:0019568]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; arabinose catabolic process [GO:0019568]	arabinose catabolic process [GO:0019568]	arabinose catabolic process [GO:0019568]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1xjqa2_d1jeda2__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1xjqb1_d2z0tc___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]		3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]		cytosol [GO:0005829]		adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	
d1xjqb2_d1m83a___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	tryptophanyl-tRNA aminoacylation [GO:0006436]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d1xjqb3_d5ee5b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; enzyme activator activity [GO:0008047]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; activation of phospholipase D activity [GO:0031584]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; intracellular protein transport [GO:0006886]; protein localization to Golgi apparatus [GO:0034067]; retrograde transport, endosome to Golgi [GO:0042147]; toxin metabolic process [GO:0009404]; vesicle-mediated transport [GO:0016192]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	activation of phospholipase D activity [GO:0031584]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; intracellular protein transport [GO:0006886]; protein localization to Golgi apparatus [GO:0034067]; retrograde transport, endosome to Golgi [GO:0042147]; toxin metabolic process [GO:0009404]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	enzyme activator activity [GO:0008047]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]
d1xjsa__d2qq4b___1			Firmicutes	Deinococcus-Thermus	cell [GO:0005623]; cytoplasm [GO:0005737]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferrous iron binding [GO:0008198]; transferase activity [GO:0016740]; cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]; iron-sulfur cluster assembly [GO:0016226]	cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]	iron-sulfur cluster assembly [GO:0016226]	cell [GO:0005623]; cytoplasm [GO:0005737]		2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferrous iron binding [GO:0008198]; transferase activity [GO:0016740]	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]
d1xjwa2_d1at1c1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d1xjwc1_d2fg6e2__1			Proteobacteria	Bacteroidetes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]
d1xjwc2_d2i6uc2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d1xjza1_d1otvb1__1	Metazoa		Chordata	Proteobacteria	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	pyrroloquinoline-quinone synthase activity [GO:0033732]; pyrroloquinoline quinone biosynthetic process [GO:0018189]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	pyrroloquinoline quinone biosynthetic process [GO:0018189]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]		enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	pyrroloquinoline-quinone synthase activity [GO:0033732]
d1xjza1_d2zvua___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1xk0a1_d2rd3a1__1	Metazoa		Chordata	Proteobacteria	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	thiaminase activity [GO:0050334]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]		enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	thiaminase activity [GO:0050334]
d1xk0b__d1p3ua___1	Metazoa		Chordata	Proteobacteria	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	heme oxidation [GO:0006788]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]		enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d1xk1a1_d1yaka___1	Metazoa		Chordata	Firmicutes	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cytosol [GO:0005829]; thiaminase activity [GO:0050334]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cytosol [GO:0005829]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	thiaminase activity [GO:0050334]
d1xk1b__d2gm8a2__1	Metazoa		Chordata	Crenarchaeota	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cytosol [GO:0005829]; thiaminase activity [GO:0050334]; thiamine metabolic process [GO:0006772]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	thiamine metabolic process [GO:0006772]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cytosol [GO:0005829]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	thiaminase activity [GO:0050334]
d1xk2b__d5uc9b___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d1xk3a__d1irma___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1xk4e__d1mr8b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d1xk4h__d1gqmf___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d1xk4j__d1wrkb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]
d1xk8a__d3opkc1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; membrane [GO:0016020]; copper ion binding [GO:0005507]; enzyme binding [GO:0019899]; protein localization [GO:0008104]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; response to metal ion [GO:0010038]	protein localization [GO:0008104]; response to metal ion [GO:0010038]	response to metal ion [GO:0010038]	extracellular exosome [GO:0070062]; membrane [GO:0016020]	cytoplasm [GO:0005737]	copper ion binding [GO:0005507]; enzyme binding [GO:0019899]	copper ion binding [GO:0005507]
d1xk8c__d1p1la___1	Metazoa		Chordata	Euryarchaeota	extracellular exosome [GO:0070062]; membrane [GO:0016020]; copper ion binding [GO:0005507]; enzyme binding [GO:0019899]; protein localization [GO:0008104]; response to metal ion [GO:0010038]	response to metal ion [GO:0010038]	protein localization [GO:0008104]; response to metal ion [GO:0010038]	response to metal ion [GO:0010038]	extracellular exosome [GO:0070062]; membrane [GO:0016020]		copper ion binding [GO:0005507]; enzyme binding [GO:0019899]	
d1xk8d__d4yb7b2__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; membrane [GO:0016020]; copper ion binding [GO:0005507]; enzyme binding [GO:0019899]; protein localization [GO:0008104]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	protein localization [GO:0008104]; response to metal ion [GO:0010038]	histidine biosynthetic process [GO:0000105]	extracellular exosome [GO:0070062]; membrane [GO:0016020]	cytoplasm [GO:0005737]	copper ion binding [GO:0005507]; enzyme binding [GO:0019899]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d1xk8f__d4yb7j2__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; membrane [GO:0016020]; copper ion binding [GO:0005507]; enzyme binding [GO:0019899]; protein localization [GO:0008104]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	protein localization [GO:0008104]; response to metal ion [GO:0010038]	histidine biosynthetic process [GO:0000105]	extracellular exosome [GO:0070062]; membrane [GO:0016020]	cytoplasm [GO:0005737]	copper ion binding [GO:0005507]; enzyme binding [GO:0019899]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d1xk9a__d4pjtd2__1		Metazoa	Proteobacteria	Chordata	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]		apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]		membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1xkfb3_d1yavb3__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; modulation by symbiont of host immune response [GO:0052553]; response to host immune response [GO:0052572]; response to hypoxia [GO:0001666]		modulation by symbiont of host immune response [GO:0052553]; response to host immune response [GO:0052572]; response to hypoxia [GO:0001666]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		metal ion binding [GO:0046872]	
d1xkfb3_d3fwsb___1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; modulation by symbiont of host immune response [GO:0052553]; response to host immune response [GO:0052572]; response to hypoxia [GO:0001666]	DNA binding [GO:0003677]; carbon catabolite repression of transcription [GO:0045013]	modulation by symbiont of host immune response [GO:0052553]; response to host immune response [GO:0052572]; response to hypoxia [GO:0001666]	carbon catabolite repression of transcription [GO:0045013]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d1xkjb__d5dqpa___1			Proteobacteria	Proteobacteria	alkanal monooxygenase (FMN-linked) activity [GO:0047646]; bioluminescence [GO:0008218]	monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	bioluminescence [GO:0008218]				alkanal monooxygenase (FMN-linked) activity [GO:0047646]	monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1xkqb__d1oc4b1__1	Metazoa		Nematoda (roundworms)	Apicomplexa	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; oxidoreductase activity [GO:0016491]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]		glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]			nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; oxidoreductase activity [GO:0016491]
d1xkyb__d4imcb___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	N-acetylneuraminate lyase activity [GO:0008747]
d1xkyd__d2r94d___1			Firmicutes	Crenarchaeota	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; carbohydrate metabolic process [GO:0005975]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]
d1xl2a__d4y36a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1xl4a1_d4alea___1			Proteobacteria	Firmicutes	integral component of membrane [GO:0016021]; inward rectifier potassium channel activity [GO:0005242]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; chitin binding [GO:0008061]; copper ion binding [GO:0005507]; monooxygenase activity [GO:0004497]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	inward rectifier potassium channel activity [GO:0005242]; metal ion binding [GO:0046872]	chitin binding [GO:0008061]; copper ion binding [GO:0005507]; monooxygenase activity [GO:0004497]
d1xl4b1_d1ft0b1__1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; inward rectifier potassium channel activity [GO:0005242]; metal ion binding [GO:0046872]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]		negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	integral component of membrane [GO:0016021]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	inward rectifier potassium channel activity [GO:0005242]; metal ion binding [GO:0046872]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]
d1xlab__d3ximb___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xlab__d5nh5b___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d1xlba__d2x7va___1			Actinobacteria	Thermotogae	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]	D-xylose metabolic process [GO:0042732]	base-excision repair [GO:0006284]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]
d1xlda__d3kbja___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xlda__d5nhbc___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d1xldb__d5nh4d___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d1xlfa__d3aala___1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; zinc ion binding [GO:0008270]; DNA repair [GO:0006281]	D-xylose metabolic process [GO:0042732]	DNA repair [GO:0006281]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; zinc ion binding [GO:0008270]
d1xlgb__d2ximd___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xljb__d1bhwc___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xljb__d1quma___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	D-xylose metabolic process [GO:0042732]	base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]
d1xlka__d1xymb___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xlkb__d1bhwb___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xllb__d1xlba___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xlnb__d3w5ud___1		Viridiplantae	Proteobacteria	Streptophyta	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]		electron transport chain [GO:0022900]; photosynthesis [GO:0015979]		chloroplast thylakoid membrane protein complex [GO:0098807]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d1xloa__d1e7pb2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]		respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d1xlpc__d3hrdd1__1			Proteobacteria	Firmicutes	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	FAD binding [GO:0071949]; nicotinate dehydrogenase activity [GO:0050138]; cofactor catabolic process [GO:0051187]		cofactor catabolic process [GO:0051187]			2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	FAD binding [GO:0071949]; nicotinate dehydrogenase activity [GO:0050138]
d1xlqa__d2b76n2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d1xlqc__d2wp9j1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]		aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d1xlsc__d3ltxa___1	Metazoa		Chordata		mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]; chromatin DNA binding [GO:0031490]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; nuclear receptor activity [GO:0004879]; nuclear receptor binding [GO:0016922]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; retinoic acid binding [GO:0001972]; retinoic acid-responsive element binding [GO:0044323]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription coactivator activity [GO:0003713]; vitamin D receptor binding [GO:0042809]; zinc ion binding [GO:0008270]; anatomical structure development [GO:0048856]; bile acid and bile salt transport [GO:0015721]; camera-type eye development [GO:0043010]; cardiac muscle cell proliferation [GO:0060038]; cell differentiation [GO:0030154]; cholesterol metabolic process [GO:0008203]; embryo implantation [GO:0007566]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; modulation by virus of host morphology or physiology [GO:0019048]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ventricular cardiac muscle cell differentiation [GO:0055012]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; vitamin metabolic process [GO:0006766]		anatomical structure development [GO:0048856]; bile acid and bile salt transport [GO:0015721]; camera-type eye development [GO:0043010]; cardiac muscle cell proliferation [GO:0060038]; cell differentiation [GO:0030154]; cholesterol metabolic process [GO:0008203]; embryo implantation [GO:0007566]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; modulation by virus of host morphology or physiology [GO:0019048]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ventricular cardiac muscle cell differentiation [GO:0055012]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; vitamin metabolic process [GO:0006766]		mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]		chromatin DNA binding [GO:0031490]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; nuclear receptor activity [GO:0004879]; nuclear receptor binding [GO:0016922]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; retinoic acid binding [GO:0001972]; retinoic acid-responsive element binding [GO:0044323]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription coactivator activity [GO:0003713]; vitamin D receptor binding [GO:0042809]; zinc ion binding [GO:0008270]	
d1xlti2_d2ji7a1__1			Proteobacteria	Proteobacteria	NAD binding [GO:0051287]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]; NADPH regeneration [GO:0006740]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	NADPH regeneration [GO:0006740]	oxalate catabolic process [GO:0033611]			NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d1xm5a__d1xaxa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; metalloendopeptidase activity [GO:0004222]; nickel cation binding [GO:0016151]; zinc ion binding [GO:0008270]; endonucleolytic cleavage involved in rRNA processing [GO:0000478]; maturation of SSU-rRNA [GO:0030490]; response to heat [GO:0009408]; ribosomal small subunit biogenesis [GO:0042274]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364]; transcription antitermination [GO:0031564]; translation [GO:0006412]	cytoplasm [GO:0005737]; endoribonuclease activity [GO:0004521]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; rRNA processing [GO:0006364]	endonucleolytic cleavage involved in rRNA processing [GO:0000478]; maturation of SSU-rRNA [GO:0030490]; response to heat [GO:0009408]; ribosomal small subunit biogenesis [GO:0042274]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364]; transcription antitermination [GO:0031564]; translation [GO:0006412]	rRNA processing [GO:0006364]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; metalloendopeptidase activity [GO:0004222]; nickel cation binding [GO:0016151]; zinc ion binding [GO:0008270]	endoribonuclease activity [GO:0004521]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1xm5d__d1atla___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; metalloendopeptidase activity [GO:0004222]; nickel cation binding [GO:0016151]; zinc ion binding [GO:0008270]; endonucleolytic cleavage involved in rRNA processing [GO:0000478]; maturation of SSU-rRNA [GO:0030490]; response to heat [GO:0009408]; ribosomal small subunit biogenesis [GO:0042274]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364]; transcription antitermination [GO:0031564]; translation [GO:0006412]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; collagen catabolic process [GO:0030574]	endonucleolytic cleavage involved in rRNA processing [GO:0000478]; maturation of SSU-rRNA [GO:0030490]; response to heat [GO:0009408]; ribosomal small subunit biogenesis [GO:0042274]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364]; transcription antitermination [GO:0031564]; translation [GO:0006412]	collagen catabolic process [GO:0030574]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; metalloendopeptidase activity [GO:0004222]; nickel cation binding [GO:0016151]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]
d1xm5d__d1tvia___1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; metalloendopeptidase activity [GO:0004222]; nickel cation binding [GO:0016151]; zinc ion binding [GO:0008270]; endonucleolytic cleavage involved in rRNA processing [GO:0000478]; maturation of SSU-rRNA [GO:0030490]; response to heat [GO:0009408]; ribosomal small subunit biogenesis [GO:0042274]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364]; transcription antitermination [GO:0031564]; translation [GO:0006412]	cytoplasm [GO:0005737]; endoribonuclease activity [GO:0004521]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; rRNA processing [GO:0006364]	endonucleolytic cleavage involved in rRNA processing [GO:0000478]; maturation of SSU-rRNA [GO:0030490]; response to heat [GO:0009408]; ribosomal small subunit biogenesis [GO:0042274]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364]; transcription antitermination [GO:0031564]; translation [GO:0006412]	rRNA processing [GO:0006364]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; metalloendopeptidase activity [GO:0004222]; nickel cation binding [GO:0016151]; zinc ion binding [GO:0008270]	endoribonuclease activity [GO:0004521]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1xmcb1_d1pd5j___1	Metazoa		Chordata	Proteobacteria	intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-octanoyltransferase activity [GO:0008458]; carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; response to drug [GO:0042493]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; response to drug [GO:0042493]	response to antibiotic [GO:0046677]	intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]		carnitine O-octanoyltransferase activity [GO:0008458]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d1xmdb1_d2ii4h___1	Metazoa	Metazoa	Chordata	Chordata	intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-octanoyltransferase activity [GO:0008458]; carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; response to drug [GO:0042493]		intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	carnitine O-octanoyltransferase activity [GO:0008458]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d1xmeb1_d1mg2o___1			Deinococcus-Thermus	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; cytochrome-c oxidase activity [GO:0004129]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1xmfb__d3wnwl___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1xmfc1_d1r2fb___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1xmgc__d1rsvb___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1xmgd__d3is8f___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1xmha__d1qghh___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1xmhb__d5d8yu___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1xmhc__d4todc___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1xmhc__d5tdta___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	toluene catabolic process [GO:0042203]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1xmma1_d5km4a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]; cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d1xmmc1_d1kpcc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]; cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d1xmmd1_d5ipea___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]; cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d1xmn.1_d1ql7a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1xmn.1_d2gx4a___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1xmn.2_d1fph.1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d1xmn.4_d3aavb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1xmol__d1euja___1		Metazoa	Deinococcus-Thermus	Chordata	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; cytokine activity [GO:0005125]; GTPase binding [GO:0051020]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; chemotaxis [GO:0006935]; defense response to virus [GO:0051607]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of glucagon secretion [GO:0070094]; response to wounding [GO:0009611]; signal transduction [GO:0007165]; tRNA aminoacylation for protein translation [GO:0006418]	translation [GO:0006412]	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; chemotaxis [GO:0006935]; defense response to virus [GO:0051607]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of glucagon secretion [GO:0070094]; response to wounding [GO:0009611]; signal transduction [GO:0007165]; tRNA aminoacylation for protein translation [GO:0006418]	ribosome [GO:0005840]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	cytokine activity [GO:0005125]; GTPase binding [GO:0051020]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]
d1xmpd__d5clia___1			Firmicutes	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d1xmpg1_d2fwpb___1			Firmicutes	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d1xmph__d3rggc___1			Firmicutes	Spirochaetes	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]
d1xmqc1_d2avyc1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1xmqe2_d5jrbh___1		Metazoa	Deinococcus-Thermus	Chordata	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	translation [GO:0006412]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]	ribosome [GO:0005840]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]
d1xmqh__d1i95h___1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1xmql__d5elna1__1			Deinococcus-Thermus	Apicomplexa	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	translation [GO:0006412]	lysyl-tRNA aminoacylation [GO:0006430]	ribosome [GO:0005840]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; nucleic acid binding [GO:0003676]
d1xmqr__d2uxbr1__1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1xmqt__d2qnhu1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1xmta__d4ufwa3__1	Viridiplantae		Streptophyta	Apicomplexa	peroxisome [GO:0005777]; histone acetyltransferase activity [GO:0004402]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]		N-terminal protein myristoylation [GO:0006499]	peroxisome [GO:0005777]		histone acetyltransferase activity [GO:0004402]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d1xmwa2_d5tpll2__1	Metazoa		Chordata		alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SH3 domain binding [GO:0017124]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; lymphocyte activation [GO:0046649]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; response to nutrient [GO:0007584]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; lymphocyte activation [GO:0046649]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; response to nutrient [GO:0007584]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]		alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SH3 domain binding [GO:0017124]; transmembrane signaling receptor activity [GO:0004888]	
d1xn1c__d1rvv2___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1xn1j__d1c2yl___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]	chloroplast [GO:0009507]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d1xn2c__d4njva___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]
d1xn3d__d2cema___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]
d1xn5a__d1z01b2__1			Firmicutes	Proteobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]						2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d1xn6a__d2k5ga1__1			Firmicutes	Proteobacteria								
d1xn6a__d4n3es___1		Viridiplantae	Firmicutes	Streptophyta		abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]				abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d1xnaa__d1xpwa___1	Metazoa	Metazoa	Chordata	Chordata	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; intraciliary transport particle B [GO:0030992]; metal ion binding [GO:0046872]; cell differentiation [GO:0030154]; heart development [GO:0007507]; intraciliary transport involved in cilium assembly [GO:0035735]; kidney development [GO:0001822]; left/right axis specification [GO:0070986]; lung development [GO:0030324]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283]	base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	cell differentiation [GO:0030154]; heart development [GO:0007507]; intraciliary transport involved in cilium assembly [GO:0035735]; kidney development [GO:0001822]; left/right axis specification [GO:0070986]; lung development [GO:0030324]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; intraciliary transport particle B [GO:0030992]	3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]	metal ion binding [GO:0046872]
d1xnba__d4hk9a___1		Fungi	Firmicutes	Ascomycota	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d1xnda__d1uaia___1	Fungi		Ascomycota	Actinobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	poly(alpha-L-guluronate) lyase activity [GO:0047491]	xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	poly(alpha-L-guluronate) lyase activity [GO:0047491]
d1xnga1_d1kh3d1__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]	NAD biosynthetic process [GO:0009435]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]	argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]
d1xnjb1_d1g8fa1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d1xnjb2_d3kt8a___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	tryptophanyl-tRNA aminoacylation [GO:0006436]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d1xnka__d1gzwb___1	Fungi	Metazoa	Ascomycota	Chordata	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	xylan catabolic process [GO:0045493]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]	endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d1xnqf__d2bxjb1__1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1xnqr__d2j02r1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1xnrc1_d3df1c1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1xnrd__d2i2ud1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d1xnwc1_d3r9qa___1			Actinobacteria	Actinobacteria	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	isomerase activity [GO:0016853]	fatty acid biosynthetic process [GO:0006633]		acetyl-CoA carboxylase complex [GO:0009317]		acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]	isomerase activity [GO:0016853]
d1xnwc2_d1sg4b___1		Metazoa	Actinobacteria	Chordata	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation [GO:0006635]	acetyl-CoA carboxylase complex [GO:0009317]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]	dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d1xnya2_d3ktkn___1			Actinobacteria	Firmicutes	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	fatty acid biosynthetic process [GO:0006633]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	acetyl-CoA carboxylase complex [GO:0009317]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]
d1xo4a__d5us1i___1				Proteobacteria		aminoglycoside 2'-N-acetyltransferase activity [GO:0047921]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]				aminoglycoside 2'-N-acetyltransferase activity [GO:0047921]
d1xo6a1_d1yg8l___1			Actinobacteria	Proteobacteria	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	fatty acid biosynthetic process [GO:0006633]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	acetyl-CoA carboxylase complex [GO:0009317]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1xo6e2_d2fw2f___1		Metazoa	Actinobacteria	Chordata	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	nucleus [GO:0005634]; histone acetyltransferase activity [GO:0004402]; transcription corepressor activity [GO:0003714]; spermatogenesis [GO:0007283]	fatty acid biosynthetic process [GO:0006633]	spermatogenesis [GO:0007283]	acetyl-CoA carboxylase complex [GO:0009317]	nucleus [GO:0005634]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]	histone acetyltransferase activity [GO:0004402]; transcription corepressor activity [GO:0003714]
d1xo7d__d1h0pa___1		Metazoa		Nematoda (roundworms)	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	cytoplasm [GO:0005737]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]	protein folding [GO:0006457]	protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]		cytoplasm [GO:0005737]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]
d1xoaa__d3zvjt1__1		Metazoa	Proteobacteria	Platyhelminthes	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1xoca1_d3gbaa1__1		Metazoa	Firmicutes	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; establishment of competence for transformation [GO:0030420]; protein transport [GO:0015031]; sporulation resulting in formation of a cellular spore [GO:0030435]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	establishment of competence for transformation [GO:0030420]; protein transport [GO:0015031]; sporulation resulting in formation of a cellular spore [GO:0030435]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	peptide transmembrane transporter activity [GO:1904680]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d1xodb2_d5ukla3__1	Metazoa	Metazoa	Chordata	Chordata	membrane [GO:0016020]; phosphatase binding [GO:0019902]; protein kinase binding [GO:0019901]; blood vessel morphogenesis [GO:0048514]; inactivation of MAPK activity [GO:0000188]; lymph vessel development [GO:0001945]; negative regulation of angiogenesis [GO:0016525]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; regulation of protein deacetylation [GO:0090311]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]	cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]; alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]; cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of catecholamine secretion [GO:0033605]; receptor internalization [GO:0031623]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	blood vessel morphogenesis [GO:0048514]; inactivation of MAPK activity [GO:0000188]; lymph vessel development [GO:0001945]; negative regulation of angiogenesis [GO:0016525]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; regulation of protein deacetylation [GO:0090311]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]	cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of catecholamine secretion [GO:0033605]; receptor internalization [GO:0031623]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	membrane [GO:0016020]	cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]	phosphatase binding [GO:0019902]; protein kinase binding [GO:0019901]	alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]
d1xoqa__d2chma1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d1xova2_d3wc5a___1		Metazoa		Chordata	helicase activity [GO:0004386]; metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	peptidoglycan catabolic process [GO:0009253]	proteolysis [GO:0006508]		extracellular space [GO:0005615]	helicase activity [GO:0004386]; metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1xoza__d2weya1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d1xpja__d1k1ek___1			Proteobacteria	Proteobacteria		3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]				3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1xpkc1_d2wu9a1__1		Viridiplantae	Firmicutes	Streptophyta	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]; acetyl-CoA C-acyltransferase activity [GO:0003988]; fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]	isoprenoid biosynthetic process [GO:0008299]	fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]		endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	acetyl-CoA C-acyltransferase activity [GO:0003988]
d1xpkc2_d4ls8b1__1			Firmicutes	Firmicutes	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]		cytosol [GO:0005829]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1xpla2_d1og9a4__1			Firmicutes		hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]		isoprenoid biosynthetic process [GO:0008299]				hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	
d1xpld2_d1cmla2__1		Viridiplantae	Firmicutes	Streptophyta	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	isoprenoid biosynthetic process [GO:0008299]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]			hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	naringenin-chalcone synthase activity [GO:0016210]
d1xpmd2_d4n45b1__1			Firmicutes		hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]		isoprenoid biosynthetic process [GO:0008299]				hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	
d1xpud2_d1otca2__1			Proteobacteria	Ciliophora	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	telomere capping [GO:0016233]	cytosol [GO:0005829]; membrane [GO:0016020]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d1xpuf2_d1iz6a2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; translational frameshifting [GO:0006452]	DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; translational frameshifting [GO:0006452]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]	ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1xpuf2_d1wydb1__1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; aspartate-tRNA(Asn) ligase activity [GO:0050560]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	aspartyl-tRNA aminoacylation [GO:0006422]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]	aspartate-tRNA(Asn) ligase activity [GO:0050560]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d1xpya1_d3thub2__1			Deinococcus-Thermus	Proteobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	menaquinone biosynthetic process [GO:0009234]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d1xpya1_d3uxkc2__1			Deinococcus-Thermus	Proteobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	menaquinone biosynthetic process [GO:0009234]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d1xpyc1_d3fj4a2__1			Deinococcus-Thermus	Proteobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]	menaquinone biosynthetic process [GO:0009234]	cellular amino acid catabolic process [GO:0009063]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d1xpyc2_d1onea2__1		Fungi	Deinococcus-Thermus	Ascomycota	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	menaquinone biosynthetic process [GO:0009234]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d1xq5b__d3pt7b___1	Metazoa	Metazoa	Chordata	Mollusca	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1xq5d__d4fh6a___1	Metazoa	Metazoa	Chordata	Annelida	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d1xq7c__d5nova___1		Metazoa		Chordata	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	protein folding [GO:0006457]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d1xq9a1_d2p9zb___1			Apicomplexa	Deinococcus-Thermus	cytosol [GO:0005829]; phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]	catalytic activity [GO:0003824]	glycolytic process [GO:0006096]		cytosol [GO:0005829]		phosphoglycerate mutase activity [GO:0004619]	catalytic activity [GO:0003824]
d1xq9b__d2p77b___1			Apicomplexa	Deinococcus-Thermus	cytosol [GO:0005829]; phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]	catalytic activity [GO:0003824]	glycolytic process [GO:0006096]		cytosol [GO:0005829]		phosphoglycerate mutase activity [GO:0004619]	catalytic activity [GO:0003824]
d1xqda__d4egna___1	Fungi		Ascomycota	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1xqda__d5w0ca1__1	Fungi	Metazoa	Ascomycota	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; (S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]		cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d1xqna__d1g9aa1__1	Viridiplantae		Streptophyta	Firmicutes	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1xqpa__d1ebma1__1		Metazoa	Crenarchaeota	Chordata	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; oxidized base lesion DNA N-glycosylase activity [GO:0000702]; base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]		mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; oxidized base lesion DNA N-glycosylase activity [GO:0000702]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]
d1xqqa__d5aekb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d1xqsb1_d4pj6a4__1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; cell-cell signaling [GO:0007267]; female pregnancy [GO:0007565]; negative regulation of cold-induced thermogenesis [GO:0120163]; peptide catabolic process [GO:0043171]; protein catabolic process [GO:0030163]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]; SMAD protein signal transduction [GO:0060395]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; cell-cell signaling [GO:0007267]; female pregnancy [GO:0007565]; negative regulation of cold-induced thermogenesis [GO:0120163]; peptide catabolic process [GO:0043171]; protein catabolic process [GO:0030163]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]; SMAD protein signal transduction [GO:0060395]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]	aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270]
d1xqva__d4bcca2__1		Metazoa	Euryarchaeota	Chordata	aminopeptidase activity [GO:0004177]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]				cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	aminopeptidase activity [GO:0004177]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d1xr0b1_d2loza___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; receptor-receptor interaction [GO:0090722]; SH2 domain binding [GO:0042169]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; auditory receptor cell development [GO:0060117]; branching involved in salivary gland morphogenesis [GO:0060445]; cell maturation [GO:0048469]; cell migration [GO:0016477]; chondrocyte differentiation [GO:0002062]; chordate embryonic development [GO:0043009]; embryonic limb morphogenesis [GO:0030326]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lung-associated mesenchyme development [GO:0060484]; MAPK cascade [GO:0000165]; mesenchymal cell differentiation [GO:0048762]; midbrain development [GO:0030901]; middle ear morphogenesis [GO:0042474]; negative regulation of fibroblast growth factor production [GO:0090272]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron migration [GO:0001764]; organ induction [GO:0001759]; outer ear morphogenesis [GO:0042473]; paraxial mesoderm development [GO:0048339]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle DNA replication [GO:1903465]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of parathyroid hormone secretion [GO:2000830]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cell differentiation [GO:0045595]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; regulation of lateral mesodermal cell fate specification [GO:0048378]; regulation of phosphate transport [GO:0010966]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular zone neuroblast division [GO:0021847]; vitamin D3 metabolic process [GO:0070640]	cell [GO:0005623]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; cellular homeostasis [GO:0019725]; collagen metabolic process [GO:0032963]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; multicellular organism growth [GO:0035264]; multicellular organismal homeostasis [GO:0048871]; negative regulation of cell population proliferation [GO:0008285]; response to muscle activity [GO:0014850]	angiogenesis [GO:0001525]; auditory receptor cell development [GO:0060117]; branching involved in salivary gland morphogenesis [GO:0060445]; cell maturation [GO:0048469]; cell migration [GO:0016477]; chondrocyte differentiation [GO:0002062]; chordate embryonic development [GO:0043009]; embryonic limb morphogenesis [GO:0030326]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lung-associated mesenchyme development [GO:0060484]; MAPK cascade [GO:0000165]; mesenchymal cell differentiation [GO:0048762]; midbrain development [GO:0030901]; middle ear morphogenesis [GO:0042474]; negative regulation of fibroblast growth factor production [GO:0090272]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron migration [GO:0001764]; organ induction [GO:0001759]; outer ear morphogenesis [GO:0042473]; paraxial mesoderm development [GO:0048339]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle DNA replication [GO:1903465]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of parathyroid hormone secretion [GO:2000830]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cell differentiation [GO:0045595]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; regulation of lateral mesodermal cell fate specification [GO:0048378]; regulation of phosphate transport [GO:0010966]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular zone neuroblast division [GO:0021847]; vitamin D3 metabolic process [GO:0070640]	cellular homeostasis [GO:0019725]; collagen metabolic process [GO:0032963]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; multicellular organismal homeostasis [GO:0048871]; multicellular organism growth [GO:0035264]; negative regulation of cell population proliferation [GO:0008285]; response to muscle activity [GO:0014850]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell [GO:0005623]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; receptor-receptor interaction [GO:0090722]; SH2 domain binding [GO:0042169]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	kinase binding [GO:0019900]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]
d1xr8a1_d1y18f1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1xr8a1_d3h7be1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1xr9a1_d4ydlc2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d1xr9b__d1h8sa1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1xr9b__d3tvmg2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1xraa2_d1p7lc1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d1xrca2_d1p7lb3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d1xrjb__d1xu4a2__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; uridine kinase activity [GO:0004849]; CTP salvage [GO:0044211]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA-dependent ATPase activity [GO:0008094]; identical protein binding [GO:0042802]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]	CTP salvage [GO:0044211]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]	cytosol [GO:0005829]		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; uridine kinase activity [GO:0004849]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA-dependent ATPase activity [GO:0008094]; identical protein binding [GO:0042802]
d1xrma__d1xrla___1			Euryarchaeota	Euryarchaeota	aminopeptidase activity [GO:0004177]	aminopeptidase activity [GO:0004177]					aminopeptidase activity [GO:0004177]	aminopeptidase activity [GO:0004177]
d1xrma__d4eusb___1			Euryarchaeota	Proteobacteria	aminopeptidase activity [GO:0004177]	hydrolase activity [GO:0016787]					aminopeptidase activity [GO:0004177]	hydrolase activity [GO:0016787]
d1xrna__d3bjmb2__1		Metazoa	Euryarchaeota	Chordata	aminopeptidase activity [GO:0004177]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	aminopeptidase activity [GO:0004177]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1xroa__d1xqwa___1			Euryarchaeota	Euryarchaeota	aminopeptidase activity [GO:0004177]	aminopeptidase activity [GO:0004177]					aminopeptidase activity [GO:0004177]	aminopeptidase activity [GO:0004177]
d1xrra__d1xqxa___1			Euryarchaeota	Euryarchaeota	aminopeptidase activity [GO:0004177]	aminopeptidase activity [GO:0004177]					aminopeptidase activity [GO:0004177]	aminopeptidase activity [GO:0004177]
d1xrva2_d1gpfa3__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]	carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1xrya__d1m4la___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1xs0a1_d1uuzb1__1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; lysozyme inhibitor activity [GO:0060241]; chaperone-mediated protein folding [GO:0061077]; regulation of catalytic activity [GO:0050790]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	chaperone-mediated protein folding [GO:0061077]; regulation of catalytic activity [GO:0050790]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme inhibitor activity [GO:0060241]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1xs1b__d4a6aj___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]		dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d1xs2d1_d3desc2__1			Deinococcus-Thermus	Thermotogae	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	menaquinone biosynthetic process [GO:0009234]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d1xs5a__d2uxac___1		Metazoa	Spirochaetes	Chordata	plasma membrane [GO:0005886]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	plasma membrane [GO:0005886]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1xs6a__d2we0a1__1			Proteobacteria		cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUTP metabolic process [GO:0046080]	cytosol [GO:0005829]		dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]
d1xs6d__d4apzd___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]		dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d1xs6f__d3tq3a___1			Proteobacteria		cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	cytosol [GO:0005829]	viral nucleocapsid [GO:0019013]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d1xsaa1_d2g74b2__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity [GO:0008803]; GTP binding [GO:0005525]; apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; nucleobase-containing compound metabolic process [GO:0006139]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; nucleobase-containing compound metabolic process [GO:0006139]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	mitochondrial matrix [GO:0005759]	cytoplasm [GO:0005737]	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity [GO:0008803]; GTP binding [GO:0005525]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]
d1xseb__d3rj9b___1	Metazoa	Metazoa	Chordata	Arthropoda	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; lung development [GO:0030324]; steroid metabolic process [GO:0008202]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]; alcohol metabolic process [GO:0006066]	lung development [GO:0030324]; steroid metabolic process [GO:0008202]	alcohol metabolic process [GO:0006066]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]
d1xsfa1_d4l41b___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; dormancy exit of symbiont in host [GO:0085016]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	dormancy exit of symbiont in host [GO:0085016]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	extracellular region [GO:0005576]; plasma membrane [GO:0005886]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	hydrolase activity [GO:0016787]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1xsib2_d3ddga2__1		Metazoa	Proteobacteria	Arthropoda	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1xsib3_d4lq1b3__1			Proteobacteria	Proteobacteria	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]		cytosol [GO:0005829]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1xsie2_d3vd9b5__1			Proteobacteria	Proteobacteria	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1xsie4_d1f49a5__1			Proteobacteria		alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	
d1xsif4_d1ukoc___1		Viridiplantae	Proteobacteria	Streptophyta	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]			alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d1xsja1_d3l4va4__1		Metazoa	Proteobacteria	Chordata	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	carbohydrate metabolic process [GO:0005975]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]		apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]
d1xsjd2_d1n7na3__1			Proteobacteria	Firmicutes	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		cell wall [GO:0005618]; extracellular region [GO:0005576]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d1xsjd3_d1xcwa1__1		Metazoa	Proteobacteria	Chordata	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1xsjd4_d3dypc3__1			Proteobacteria	Proteobacteria	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1xsje2_d1f4ab4__1			Proteobacteria	Proteobacteria	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1xsjf4_d5cgta4__1			Proteobacteria	Firmicutes	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1xska4_d4cd4a___1			Proteobacteria	Proteobacteria	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; substituted mannan metabolic process [GO:0006080]	carbohydrate metabolic process [GO:0005975]	substituted mannan metabolic process [GO:0006080]			alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]
d1xskc2_d2ow6a2__1		Metazoa	Proteobacteria	Arthropoda	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1xskd2_d3t08c5__1			Proteobacteria	Proteobacteria	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1xskd3_d3edea3__1			Proteobacteria	Bacteroidetes	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d1xskd4_d3w38a2__1		Viridiplantae	Proteobacteria	Streptophyta	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]	carbohydrate metabolic process [GO:0005975]				alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]
d1xske2_d1v7xa2__1			Proteobacteria	Proteobacteria	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; transferase activity [GO:0016740]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d1xskf2_d3vd3a5__1			Proteobacteria	Proteobacteria	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1xskf4_d3aiua___1		Viridiplantae	Proteobacteria	Streptophyta	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		chloroplast [GO:0009507]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	beta-glucosidase activity [GO:0008422]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; scopolin beta-glucosidase activity [GO:0102483]
d1xsla3_d1ylqa1__1	Metazoa		Chordata	Euryarchaeota	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	nucleotidyltransferase activity [GO:0016779]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]		nucleoplasm [GO:0005654]; nucleus [GO:0005634]		5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	nucleotidyltransferase activity [GO:0016779]
d1xslm3_d1fa0b4__1	Metazoa	Fungi	Chordata	Ascomycota	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d1xsna1_d1xsli1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d1xspa1_d8icna1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d1xt8b__d1xc1a___1			Proteobacteria	Proteobacteria		periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]		ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]		periplasmic space [GO:0042597]		metal ion binding [GO:0046872]
d1xt9b__d3m3ja___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1xtab1_d2ddbd1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1xtba__d5ltza___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]
d1xtbb__d1x9ia___1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]; carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]
d1xtce__d1jr0e___1			Proteobacteria	Proteobacteria	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d1xtcg__d1jckd1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1xtfa1_d1g9da3__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1xtfb1_d3b92a___1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	negative regulation of neurotransmitter secretion [GO:0046929]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d1xtga1_d1os9e1__1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	negative regulation of neurotransmitter secretion [GO:0046929]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1xtga1_d4ks6a1__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1xtka1_d2jlya1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; transcription export complex [GO:0000346]; ATP binding [GO:0005524]; ATP-dependent protein binding [GO:0043008]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-dependent ATPase activity [GO:0008186]; U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070]; liver development [GO:0001889]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; RNA export from nucleus [GO:0006405]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	liver development [GO:0001889]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; RNA export from nucleus [GO:0006405]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; transcription export complex [GO:0000346]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; ATP-dependent protein binding [GO:0043008]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; RNA helicase activity [GO:0003724]; U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1xtmb__d4rvpf___1		Viridiplantae	Firmicutes	Streptophyta	plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; removal of superoxide radicals [GO:0019430]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	removal of superoxide radicals [GO:0019430]		plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1xttc__d1o5oa1__1			Crenarchaeota	Thermotogae	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytosol [GO:0005829]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]		cytosol [GO:0005829]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]
d1xttc__d5eswa1__1			Crenarchaeota	Proteobacteria	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	nucleoside metabolic process [GO:0009116]			GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]
d1xtua__d3hvuc1__1			Crenarchaeota	Firmicutes	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]		cytoplasm [GO:0005737]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1xtuc__d1p18b___1			Crenarchaeota		GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]		cytoplasm [GO:0005737]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1xtuc__d3naga1__1			Crenarchaeota	Euryarchaeota	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]		cytoplasm [GO:0005737]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]
d1xtug__d2ehjb1__1			Crenarchaeota	Proteobacteria	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytosol [GO:0005829]; membrane [GO:0016020]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]		cytosol [GO:0005829]; membrane [GO:0016020]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]
d1xtvc__d2hcrb1__1		Metazoa	Crenarchaeota	Chordata	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]
d1xtve__d1jlra___1			Crenarchaeota	Apicomplexa	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]			GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]
d1xtvg__d2ehja1__1			Crenarchaeota	Proteobacteria	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytosol [GO:0005829]; membrane [GO:0016020]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]		cytosol [GO:0005829]; membrane [GO:0016020]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	GTP binding [GO:0005525]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]
d1xu3c__d2iy4y___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]		cell [GO:0005623]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1xu5a__d3e1lc___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1xu5c__d1afrf___1		Viridiplantae	Proteobacteria	Streptophyta	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	fatty acid biosynthetic process [GO:0006633]		chloroplast [GO:0009507]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d1xu5d__d5d8xg___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1xu7a1_d1v6aa1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	cytoplasm [GO:0005737]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	L-lactate dehydrogenase activity [GO:0004459]
d1xu7c1_d3orfd___1	Metazoa		Chordata		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytoplasm [GO:0005737]; phagocytic vesicle [GO:0045335]; 6,7-dihydropteridine reductase activity [GO:0004155]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; L-phenylalanine catabolic process [GO:0006559]; response to oxidative stress [GO:0006979]; tetrahydrobiopterin biosynthetic process [GO:0006729]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	L-phenylalanine catabolic process [GO:0006559]; response to oxidative stress [GO:0006979]; tetrahydrobiopterin biosynthetic process [GO:0006729]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	cytoplasm [GO:0005737]; phagocytic vesicle [GO:0045335]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	6,7-dihydropteridine reductase activity [GO:0004155]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]
d1xu9a1_d1v9lc1__1	Metazoa		Chordata	Crenarchaeota	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cellular amino acid metabolic process [GO:0006520]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1xu9b1_d4l76a1__1	Metazoa		Chordata	Euryarchaeota	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	potassium ion transport [GO:0006813]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1xuaa1_d4duna1__1			Proteobacteria	Firmicutes	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	catalytic activity [GO:0003824]; biosynthetic process [GO:0009058]	pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	biosynthetic process [GO:0009058]			trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]	catalytic activity [GO:0003824]
d1xuaa2_d4juub___1			Proteobacteria	Proteobacteria	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	4-hydroxyproline epimerase activity [GO:0047580]	pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]				trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]	4-hydroxyproline epimerase activity [GO:0047580]
d1xuab2_d3g7kb1__1			Proteobacteria	Firmicutes	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	methylitaconate delta-isomerase activity [GO:0050100]; cofactor catabolic process [GO:0051187]	pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	cofactor catabolic process [GO:0051187]			trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]	methylitaconate delta-isomerase activity [GO:0050100]
d1xuba2_d1qyab1__1			Proteobacteria	Proteobacteria	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	isomerase activity [GO:0016853]; biosynthetic process [GO:0009058]	pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	biosynthetic process [GO:0009058]			trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]	isomerase activity [GO:0016853]
d1xudb__d3fu3a2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1xuka__d1qy6a___1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; pathogenesis [GO:0009405]	digestion [GO:0007586]; proteolysis [GO:0006508]	pathogenesis [GO:0009405]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d1xupo1_d1boto1__1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]		cytosol [GO:0005829]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d1xupo1_d5aqoc1__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d1xupx1_d4wq4d1__1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	tRNA threonylcarbamoyladenosine modification [GO:0002949]		cytosol [GO:0005829]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]
d1xura__d1y93a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1xurb__d3fh8a2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1xurb__d4h82b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1xuua1_d4ipia2__1			Proteobacteria	Proteobacteria	catalytic activity [GO:0003824]; carbohydrate biosynthetic process [GO:0016051]	catalytic activity [GO:0003824]; carbohydrate biosynthetic process [GO:0016051]	carbohydrate biosynthetic process [GO:0016051]	carbohydrate biosynthetic process [GO:0016051]			catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d1xv1a__d3f3yc___1		Metazoa		Chordata		cytosol [GO:0005829]; bile-salt sulfotransferase activity [GO:0047704]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; bile acid catabolic process [GO:0030573]; ethanol catabolic process [GO:0006068]; lipid catabolic process [GO:0016042]; regulation of lipid metabolic process [GO:0019216]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]		3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; bile acid catabolic process [GO:0030573]; ethanol catabolic process [GO:0006068]; lipid catabolic process [GO:0016042]; regulation of lipid metabolic process [GO:0019216]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]		cytosol [GO:0005829]		bile-salt sulfotransferase activity [GO:0047704]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]
d1xv8a2_d1e3za2__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d1xv8a2_d5fd0a2__1	Metazoa		Chordata	Actinobacteria	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	beta-N-acetylhexosaminidase activity [GO:0004563]
d1xv8b2_d2vzta3__1	Metazoa		Chordata	Actinobacteria	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1xv9b__d5apka1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d1xv9c__d2ouza___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transcriptional preinitiation complex [GO:0097550]; transcriptionally active chromatin [GO:0035327]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor activity [GO:0030284]; estrogen receptor binding [GO:0030331]; estrogen response element binding [GO:0034056]; identical protein binding [GO:0042802]; nitric-oxide synthase regulator activity [GO:0030235]; nuclear receptor activity [GO:0004879]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; steroid binding [GO:0005496]; TBP-class protein binding [GO:0017025]; TFIIB-class transcription factor binding [GO:0001093]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; androgen metabolic process [GO:0008209]; antral ovarian follicle growth [GO:0001547]; cellular response to estradiol stimulus [GO:0071392]; cellular response to estrogen stimulus [GO:0071391]; chromatin remodeling [GO:0006338]; epithelial cell development [GO:0002064]; epithelial cell proliferation involved in mammary gland duct elongation [GO:0060750]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; male gonad development [GO:0008584]; mammary gland alveolus development [GO:0060749]; mammary gland branching involved in pregnancy [GO:0060745]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; protein deubiquitination [GO:0016579]; protein localization to chromatin [GO:0071168]; regulation of apoptotic process [GO:0042981]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of inflammatory response [GO:0050727]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; signal transduction [GO:0007165]; stem cell differentiation [GO:0048863]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]; uterus development [GO:0060065]; vagina development [GO:0060068]	androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	androgen metabolic process [GO:0008209]; antral ovarian follicle growth [GO:0001547]; cellular response to estradiol stimulus [GO:0071392]; cellular response to estrogen stimulus [GO:0071391]; chromatin remodeling [GO:0006338]; epithelial cell development [GO:0002064]; epithelial cell proliferation involved in mammary gland duct elongation [GO:0060750]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; male gonad development [GO:0008584]; mammary gland alveolus development [GO:0060749]; mammary gland branching involved in pregnancy [GO:0060745]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; protein deubiquitination [GO:0016579]; protein localization to chromatin [GO:0071168]; regulation of apoptotic process [GO:0042981]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of inflammatory response [GO:0050727]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; signal transduction [GO:0007165]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; uterus development [GO:0060065]; vagina development [GO:0060068]	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transcriptionally active chromatin [GO:0035327]; transcriptional preinitiation complex [GO:0097550]	androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]	ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor activity [GO:0030284]; estrogen receptor binding [GO:0030331]; estrogen response element binding [GO:0034056]; identical protein binding [GO:0042802]; nitric-oxide synthase regulator activity [GO:0030235]; nuclear receptor activity [GO:0004879]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; steroid binding [GO:0005496]; TBP-class protein binding [GO:0017025]; TFIIB-class transcription factor binding [GO:0001093]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1xvba__d3re7o___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1xvbc__d3dhia___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	toluene catabolic process [GO:0042203]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1xvbd__d5jkle___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1xvca__d1yuzb1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]			cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1xvcc__d1umnf___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d1xvda__d1oq7c___1		Viridiplantae	Proteobacteria	Streptophyta	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	fatty acid biosynthetic process [GO:0006633]		chloroplast [GO:0009507]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d1xvda__d4tohb___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1xvdb__d3q3oa___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	toluene catabolic process [GO:0042203]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1xvdb__d5ww6b___1			Proteobacteria	Actinobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1xvdd__d4ii4c1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	phenylacetate catabolic process [GO:0010124]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	
d1xvdf__d1mhzg___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	methane monooxygenase activity [GO:0015049]; methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	methane monooxygenase activity [GO:0015049]
d1xvea__d5up7a___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1xveb__d3vpma1__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]		cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1xvfa__d3qd8o1__1			Proteobacteria	Actinobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1xvfb__d1xikb___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1xvfc__d1h0oa___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]		cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1xvgc__d2cwla1__1			Proteobacteria	Deinococcus-Thermus	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]		cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]				metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	
d1xvgd__d4p18v___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1xvja__d3fs7e___1	Metazoa	Metazoa	Chordata	Chordata	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cochlea development [GO:0090102]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]	cochlea development [GO:0090102]		cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]
d1xvlb__d5kzjb___1			Cyanobacteria	Proteobacteria	metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]			metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1xvma__d3rxva___1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1xvva__d2vjkb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; carnitine dehydratase activity [GO:0008735]; CoA-transferase activity [GO:0008410]; carnitine catabolic process [GO:0042413]	cytoplasm [GO:0005737]; formyl-CoA transferase activity [GO:0033608]; oxalate catabolic process [GO:0033611]	carnitine catabolic process [GO:0042413]	oxalate catabolic process [GO:0033611]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	carnitine dehydratase activity [GO:0008735]; CoA-transferase activity [GO:0008410]	formyl-CoA transferase activity [GO:0033608]
d1xvya__d5icta1__1		Metazoa	Proteobacteria	Arthropoda	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; ionotropic glutamate receptor complex [GO:0008328]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; cation transport [GO:0006812]; modulation of chemical synaptic transmission [GO:0050804]; synaptic transmission, glutamatergic [GO:0035249]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	cation transport [GO:0006812]; modulation of chemical synaptic transmission [GO:0050804]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; ionotropic glutamate receptor complex [GO:0008328]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]	metal ion binding [GO:0046872]	AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1xw2a1_d3qt9a___1			Proteobacteria	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	catalytic activity [GO:0003824]	xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	catalytic activity [GO:0003824]
d1xw3a1_d1vz0e2__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]; cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	DNA binding [GO:0003677]; chromosome segregation [GO:0007059]	cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	chromosome segregation [GO:0007059]	cytosol [GO:0005829]		ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]	DNA binding [GO:0003677]
d1xw5a1_d4pnfd2__1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytoplasm [GO:0005737]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione transferase activity [GO:0004364]
d1xw6c1_d2on7c2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	
d1xw6c2_d1k0ab2__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	cytoplasm [GO:0005737]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]
d1xw9a__d2xpda___1	Metazoa		Arthropoda	Proteobacteria	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; nucleus [GO:0005634]	cell [GO:0005623]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]	thioredoxin peroxidase activity [GO:0008379]
d1xw9c__d1gh2a___1	Metazoa	Metazoa	Arthropoda	Chordata	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; proteasome complex [GO:0000502]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]	disulfide oxidoreductase activity [GO:0015036]
d1xw9d__d1eema2__1	Metazoa	Metazoa	Arthropoda	Chordata	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d1xwaa1_d5a4wc1__1	Metazoa	Viridiplantae	Arthropoda	Streptophyta	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell [GO:0005623]; nucleus [GO:0005634]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d1xwab__d2yana1__1	Metazoa	Metazoa	Arthropoda	Chordata	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; [2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	[2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]	cell [GO:0005623]; nucleus [GO:0005634]	cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]	electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]
d1xwac__d5b6ma___1	Metazoa	Metazoa	Arthropoda	Chordata	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; cadherin binding [GO:0045296]; calcium-independent phospholipase A2 activity [GO:0047499]; glutathione peroxidase activity [GO:0004602]; peroxiredoxin activity [GO:0051920]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; protein homodimerization activity [GO:0042803]; ubiquitin protein ligase binding [GO:0031625]; cell redox homeostasis [GO:0045454]; cellular oxidant detoxification [GO:0098869]; cellular response to oxidative stress [GO:0034599]; glycerophospholipid catabolic process [GO:0046475]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; cellular oxidant detoxification [GO:0098869]; cellular response to oxidative stress [GO:0034599]; glycerophospholipid catabolic process [GO:0046475]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; nucleus [GO:0005634]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]	cadherin binding [GO:0045296]; calcium-independent phospholipase A2 activity [GO:0047499]; glutathione peroxidase activity [GO:0004602]; peroxiredoxin activity [GO:0051920]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; protein homodimerization activity [GO:0042803]; ubiquitin protein ligase binding [GO:0031625]
d1xwac__d5g30d___1	Metazoa	Metazoa	Arthropoda	Arthropoda	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; nucleus [GO:0005634]	cell [GO:0005623]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d1xwba__d2pu9c___1	Metazoa	Viridiplantae	Arthropoda	Streptophyta	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; chloroplast [GO:0009507]; cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; nucleus [GO:0005634]	cell [GO:0005623]; chloroplast [GO:0009507]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]	
d1xwbc__d3iast___1	Metazoa		Arthropoda	Deinococcus-Thermus	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; nucleus [GO:0005634]	plasma membrane [GO:0005886]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]	quinone binding [GO:0048038]
d1xwbd__d3csjb2__1	Metazoa	Metazoa	Arthropoda	Chordata	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d1xwdf__d3g04c___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; follicle-stimulating hormone receptor activity [GO:0004963]; G protein-coupled peptide receptor activity [GO:0008528]; activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; female gamete generation [GO:0007292]; female gonad development [GO:0008585]; follicle-stimulating hormone signaling pathway [GO:0042699]; G protein-coupled receptor signaling pathway [GO:0007186]; gonad development [GO:0008406]; hormone-mediated signaling pathway [GO:0009755]; male gonad development [GO:0008584]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of protein kinase A signaling [GO:0010738]; spermatogenesis [GO:0007283]	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]; activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; female gamete generation [GO:0007292]; female gonad development [GO:0008585]; follicle-stimulating hormone signaling pathway [GO:0042699]; gonad development [GO:0008406]; G protein-coupled receptor signaling pathway [GO:0007186]; hormone-mediated signaling pathway [GO:0009755]; male gonad development [GO:0008584]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of protein kinase A signaling [GO:0010738]; spermatogenesis [GO:0007283]	activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	follicle-stimulating hormone receptor activity [GO:0004963]; G protein-coupled peptide receptor activity [GO:0008528]	G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]
d1xwfa1_d1zmtb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]		adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	
d1xwfb1_d1j49b1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]		adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]
d1xwfb1_d2yz7a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]		adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]
d1xwfd1_d3tscb___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]		adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1xwgb1_d2c3tb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]
d1xwka2_d4maba___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	cell [GO:0005623]; cytosol [GO:0005829]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	thioredoxin peroxidase activity [GO:0008379]
d1xwkb2_d3gtuc2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]
d1xwkc1_d4ofmb2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	transferase activity [GO:0016740]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	transferase activity [GO:0016740]
d1xwya1_d1wxza___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 3'-5'-exoribonuclease activity [GO:0000175]; deoxyribonuclease activity [GO:0004536]; endodeoxyribonuclease activity, producing 5'-phosphomonoesters [GO:0016888]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; single-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008310]; DNA catabolic process, exonucleolytic [GO:0000738]; response to hydrogen peroxide [GO:0042542]; RNA phosphodiester bond hydrolysis [GO:0090501]	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]; adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	DNA catabolic process, exonucleolytic [GO:0000738]; response to hydrogen peroxide [GO:0042542]; RNA phosphodiester bond hydrolysis [GO:0090501]	adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]	3'-5'-exoribonuclease activity [GO:0000175]; deoxyribonuclease activity [GO:0004536]; endodeoxyribonuclease activity, producing 5'-phosphomonoesters [GO:0016888]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; single-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008310]	adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]
d1xx0a1_d1x1fa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]; actin cytoskeleton reorganization [GO:0031532]; cell projection organization [GO:0030030]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G protein-coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin-activated receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; macrophage colony-stimulating factor receptor binding [GO:0005157]; phospholipid binding [GO:0005543]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; SH3/SH2 adaptor activity [GO:0005070]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; cellular response to lipopolysaccharide [GO:0071222]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of macrophage colony-stimulating factor signaling pathway [GO:1902227]; negative regulation of microglial cell migration [GO:1904140]; negative regulation of phosphorylation [GO:0042326]; negative regulation of ruffle assembly [GO:1900028]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of gene expression [GO:0010628]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of phagocytosis, engulfment [GO:0060100]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin cytoskeleton reorganization [GO:0031532]; cell projection organization [GO:0030030]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G protein-coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin-activated receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904]	cellular response to lipopolysaccharide [GO:0071222]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of macrophage colony-stimulating factor signaling pathway [GO:1902227]; negative regulation of microglial cell migration [GO:1904140]; negative regulation of phosphorylation [GO:0042326]; negative regulation of ruffle assembly [GO:1900028]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of gene expression [GO:0010628]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of phagocytosis, engulfment [GO:0060100]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]	macrophage colony-stimulating factor receptor binding [GO:0005157]; phospholipid binding [GO:0005543]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; SH3/SH2 adaptor activity [GO:0005070]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]
d1xx0a1_d2d2qb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]; actin cytoskeleton reorganization [GO:0031532]; cell projection organization [GO:0030030]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G protein-coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin-activated receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin cytoskeleton reorganization [GO:0031532]; cell projection organization [GO:0030030]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G protein-coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin-activated receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d1xx5a1_d2ddad1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1xx5b1_d2ddaa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1xx5c1_d2ddbc1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1xxae__d5cj9a2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1xxba__d1f9na2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1xxba__d2zfzb___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1xxbe__d1f9nf2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1xxcc__d3bued___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1xxce__d3cagc___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1xxcf__d3cage___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1xxea2_d2ierb2__1			Aquificae	Aquificae	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	lipid A biosynthetic process [GO:0009245]	lipid A biosynthetic process [GO:0009245]			metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d1xxhg2_d1xdba___1			Proteobacteria	Proteobacteria	DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA-dependent DNA replication [GO:0006261]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	DNA-dependent DNA replication [GO:0006261]	nitrogen fixation [GO:0009399]	DNA polymerase III complex [GO:0009360]	molybdenum-iron nitrogenase complex [GO:0016612]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1xxhh1_d1sxjb1__1		Fungi	Proteobacteria	Ascomycota	DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA-dependent DNA replication [GO:0006261]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	DNA polymerase III complex [GO:0009360]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]
d1xxif1_d1sxjc1__1		Fungi	Proteobacteria	Ascomycota	DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA-dependent DNA replication [GO:0006261]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	DNA polymerase III complex [GO:0009360]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]
d1xxij2_d5ik2m2__1			Proteobacteria	Firmicutes	DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA-dependent DNA replication [GO:0006261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	DNA-dependent DNA replication [GO:0006261]	ATP synthesis coupled proton transport [GO:0015986]	DNA polymerase III complex [GO:0009360]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1xxja1_d1wplb___1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]
d1xxja1_d2yzdf2__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1xxja2_d1n3sj___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1xxjb1_d1a8rg___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1xxjd1_d4d19a2__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1xxjd2_d1sqlf___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytosol [GO:0005829]	urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]
d1xxjd2_d1xy3d1__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1xxmc__d1jtgd___1			Proteobacteria	Proteobacteria	beta-lactamase activity [GO:0008800]; beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]	beta-lactamase activity [GO:0008800]; beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]	beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]	beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]			beta-lactamase activity [GO:0008800]	beta-lactamase activity [GO:0008800]
d1xxna__d1v6nb___1		Viridiplantae	Firmicutes	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1xxpa1_d3mmjb___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	protein tyrosine phosphatase activity [GO:0004725]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]		protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d1xxqa__d1ugy.2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]
d1xxqc__d1uh1.1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]
d1xxrb__d4akda1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d1xxrd__d2gueb1__1	Viridiplantae		Streptophyta	Rhodophyta	carbohydrate binding [GO:0030246]	cell [GO:0005623]; carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]				cell [GO:0005623]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]
d1xxtc__d2vmlh___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1xxtc__d3heoa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1xxub__d1meka___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; response to nitrosative stress [GO:0051409]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; procollagen-proline 4-dioxygenase complex [GO:0016222]; enzyme binding [GO:0019899]; integrin binding [GO:0005178]; peptide disulfide oxidoreductase activity [GO:0015037]; procollagen-proline 4-dioxygenase activity [GO:0004656]; protein disulfide isomerase activity [GO:0003756]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-7 [GO:0098761]; chylomicron assembly [GO:0034378]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; protein folding [GO:0006457]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976]; very-low-density lipoprotein particle assembly [GO:0034379]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; response to nitrosative stress [GO:0051409]	cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-7 [GO:0098761]; chylomicron assembly [GO:0034378]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; protein folding [GO:0006457]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976]; very-low-density lipoprotein particle assembly [GO:0034379]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; procollagen-proline 4-dioxygenase complex [GO:0016222]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]	enzyme binding [GO:0019899]; integrin binding [GO:0005178]; peptide disulfide oxidoreductase activity [GO:0015037]; procollagen-proline 4-dioxygenase activity [GO:0004656]; protein disulfide isomerase activity [GO:0003756]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1xxuc__d4dvca1__1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; response to nitrosative stress [GO:0051409]	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; pathogenesis [GO:0009405]; protein folding [GO:0006457]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; response to nitrosative stress [GO:0051409]	cell redox homeostasis [GO:0045454]; pathogenesis [GO:0009405]; protein folding [GO:0006457]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; periplasmic space [GO:0042597]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d1xxvb1_d4az1b___1			Proteobacteria		extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	protein tyrosine phosphatase activity [GO:0004725]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]		protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d1xxwb__d3u8da___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]; antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]
d1xy0a__d4l2mb___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1xy3a2_d1gtpp___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1xy3a2_d2yzce1__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1xy3b1_d1vaxg2__1	Fungi		Ascomycota		peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	
d1xy3c1_d1n3sc___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d1xy3c2_d1sqld___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytosol [GO:0005829]	urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]
d1xy3d2_d4mb8d2__1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1xy3e1_d5ll1e2__1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d1xy3e2_d3qnac___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	queuosine biosynthetic process [GO:0008616]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d1xy3g2_d2o9ma___1	Fungi		Ascomycota		peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	
d1xy3h2_d1vayc1__1	Fungi		Ascomycota		peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	
d1xyba__d1ximd___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xybb__d3n4aa___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xyca__d1xlmb___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d1xyda__d3buwb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	B cell receptor complex [GO:0019815]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early phagosome [GO:0032009]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T cell receptor complex [GO:0042101]; ATP binding [GO:0005524]; integrin binding [GO:0005178]; interleukin-15 receptor binding [GO:0016170]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatase binding [GO:0019902]; phosphotyrosine residue binding [GO:0001784]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; Toll-like receptor binding [GO:0035325]; activation of JUN kinase activity [GO:0007257]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; B cell receptor signaling pathway [GO:0050853]; beta selection [GO:0043366]; blood vessel morphogenesis [GO:0048514]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to molecule of fungal origin [GO:0071226]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; interleukin-3-mediated signaling pathway [GO:0038156]; leukocyte activation involved in immune response [GO:0002366]; leukocyte cell-cell adhesion [GO:0007159]; leukotriene biosynthetic process [GO:0019370]; lymph vessel development [GO:0001945]; macrophage activation involved in immune response [GO:0002281]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine phosphorylation [GO:0018105]; platelet activation [GO:0030168]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of bone resorption [GO:0045780]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0045425]; positive regulation of interleukin-10 biosynthetic process [GO:0045082]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of interleukin-3 biosynthetic process [GO:0045401]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of receptor internalization [GO:0002092]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of type I interferon production [GO:0032481]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; receptor internalization [GO:0031623]; regulation of arachidonic acid secretion [GO:0090237]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neutrophil degranulation [GO:0043313]; regulation of phagocytosis [GO:0050764]; regulation of platelet activation [GO:0010543]; regulation of platelet aggregation [GO:0090330]; regulation of superoxide anion generation [GO:0032928]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; serotonin secretion by platelet [GO:0002554]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral process [GO:0016032]	astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	activation of JUN kinase activity [GO:0007257]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; B cell receptor signaling pathway [GO:0050853]; beta selection [GO:0043366]; blood vessel morphogenesis [GO:0048514]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to molecule of fungal origin [GO:0071226]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; interleukin-3-mediated signaling pathway [GO:0038156]; leukocyte activation involved in immune response [GO:0002366]; leukocyte cell-cell adhesion [GO:0007159]; leukotriene biosynthetic process [GO:0019370]; lymph vessel development [GO:0001945]; macrophage activation involved in immune response [GO:0002281]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine phosphorylation [GO:0018105]; platelet activation [GO:0030168]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of bone resorption [GO:0045780]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0045425]; positive regulation of interleukin-10 biosynthetic process [GO:0045082]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of interleukin-3 biosynthetic process [GO:0045401]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of receptor internalization [GO:0002092]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of type I interferon production [GO:0032481]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; receptor internalization [GO:0031623]; regulation of arachidonic acid secretion [GO:0090237]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neutrophil degranulation [GO:0043313]; regulation of phagocytosis [GO:0050764]; regulation of platelet activation [GO:0010543]; regulation of platelet aggregation [GO:0090330]; regulation of superoxide anion generation [GO:0032928]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; serotonin secretion by platelet [GO:0002554]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral process [GO:0016032]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	B cell receptor complex [GO:0019815]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early phagosome [GO:0032009]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T cell receptor complex [GO:0042101]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; integrin binding [GO:0005178]; interleukin-15 receptor binding [GO:0016170]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatase binding [GO:0019902]; phosphotyrosine residue binding [GO:0001784]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; Toll-like receptor binding [GO:0035325]
d1xydb__d2ovkc___1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]		astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	
d1xyea__d1k0yc___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1xyec__d3ba2a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1xyed__d4f4og___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1xyfa2_d4b3lc___1			Actinobacteria	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d1xyga2_d1ebub2__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; nucleolus [GO:0005730]; copper ion binding [GO:0005507]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]; response to cadmium ion [GO:0046686]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; homoserine dehydrogenase activity [GO:0004412]; NADP binding [GO:0050661]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	arginine biosynthetic process [GO:0006526]; response to cadmium ion [GO:0046686]	homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; nucleolus [GO:0005730]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	copper ion binding [GO:0005507]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]	homoserine dehydrogenase activity [GO:0004412]; NADP binding [GO:0050661]
d1xygb2_d1onpa3__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; nucleolus [GO:0005730]; copper ion binding [GO:0005507]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]; response to cadmium ion [GO:0046686]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	arginine biosynthetic process [GO:0006526]; response to cadmium ion [GO:0046686]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; nucleolus [GO:0005730]		copper ion binding [GO:0005507]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]
d1xymb__d5nhcb___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d1xyna__d1igob___1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d1xyoa1_d1w6qb___1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	xylan catabolic process [GO:0045493]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]	endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d1xyr11_d1ncq.1__1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1xyva__d1czha___1			Proteobacteria	Cyanobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1xyzb__d3rikd2__1		Metazoa	Firmicutes	Chordata	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan endo-1,3-beta-xylosidase activity [GO:0033905]; xylan catabolic process [GO:0045493]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	xylan catabolic process [GO:0045493]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan endo-1,3-beta-xylosidase activity [GO:0033905]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d1xz0a1_d3pwpe1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1xz0b__d5jr1l2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1xz0c1_d5sv4a___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1xz2c__d3v57a___1	Metazoa		Chordata	Rhodophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1xz2d__d1bbbc___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1xz4a__d2hbsc___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1xz5c__d1c40a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1xz7b__d4h0mu___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1xz7c__d1s5xa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1xzba__d5llsb2__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	cutinase activity [GO:0050525]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d1xzca__d1ffda___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	cutinase activity [GO:0050525]	cutinase activity [GO:0050525]
d1xzca__d3hrha___1	Fungi		Ascomycota	Actinobacteria	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	cell wall [GO:0005618]; extracellular region [GO:0005576]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]		glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	cutinase activity [GO:0050525]	diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]
d1xzda__d2qvbb___1	Fungi		Ascomycota	Actinobacteria	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; haloalkane dehalogenase activity [GO:0018786]; halogenated hydrocarbon catabolic process [GO:0042206]		halogenated hydrocarbon catabolic process [GO:0042206]	extracellular region [GO:0005576]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	cutinase activity [GO:0050525]	haloalkane dehalogenase activity [GO:0018786]
d1xzha__d3kdab1__1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	hydrolase activity [GO:0016787]			extracellular region [GO:0005576]		cutinase activity [GO:0050525]	hydrolase activity [GO:0016787]
d1xzja__d3kwfb2__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cutinase activity [GO:0050525]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1xzkb__d3esca___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	cutinase activity [GO:0050525]	cutinase activity [GO:0050525]
d1xzkb__d4dnqj___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	hydrolase activity, acting on ester bonds [GO:0016788]; secondary shoot formation [GO:0010223]; strigolactone biosynthetic process [GO:1901601]		secondary shoot formation [GO:0010223]; strigolactone biosynthetic process [GO:1901601]	extracellular region [GO:0005576]		cutinase activity [GO:0050525]	hydrolase activity, acting on ester bonds [GO:0016788]
d1xzla__d1xzha___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	cutinase activity [GO:0050525]	cutinase activity [GO:0050525]
d1xzqa3_d1wosa2__1			Thermotogae	Thermotogae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]	cytosol [GO:0005829]; aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]; glycine decarboxylation via glycine cleavage system [GO:0019464]	tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]	glycine decarboxylation via glycine cleavage system [GO:0019464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]	aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]
d1xzud__d5b13h___1	Metazoa		Chordata	Rhodophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1xzva__d1hgba___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1xzva__d4rmpa1__1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1xzwa2_d4dhlc2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]
d1xzwb3_d4kkza1__1	Viridiplantae		Streptophyta		extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]				extracellular region [GO:0005576]		acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	
d1y09c__d3a9ma___1	Metazoa	Metazoa	Chordata	Arthropoda	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y09c__d3ng6b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y0ca__d1j7sc___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y0da__d3uhna___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y0db__d1y7dd___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y0dd__d2blha___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y0ga__d5ixgb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]				periplasmic space [GO:0042597]			
d1y0gb__d3hpeb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]				periplasmic space [GO:0042597]			
d1y0gc__d1wuba___1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]				periplasmic space [GO:0042597]			
d1y0gd__d5ixgd___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]				periplasmic space [GO:0042597]			
d1y0ha__d4nl5b___1			Actinobacteria	Actinobacteria	monooxygenase activity [GO:0004497]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; heme catabolic process [GO:0042167]		heme catabolic process [GO:0042167]		cell wall [GO:0005618]; plasma membrane [GO:0005886]	monooxygenase activity [GO:0004497]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d1y0lb2_d3ch1j2__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1y0ld2_d4pp2a2__1		Metazoa		Arthropoda		extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]				extracellular region [GO:0005576]		cysteine-type peptidase activity [GO:0008234]
d1y0lf1_d1n0xl1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1y0lf1_d4jo3m1__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1y0lf2_d4xbpl1__1												
d1y0lh2_d4alal1__1						host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]		fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]		host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		protein dimerization activity [GO:0046983]
d1y0ll2_d3bd3b___1												
d1y0oa__d2pbcc1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; chloroplast thylakoid lumen [GO:0009543]; plastid [GO:0009536]; thylakoid lumen [GO:0031977]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]			chloroplast [GO:0009507]; chloroplast thylakoid lumen [GO:0009543]; plastid [GO:0009536]; thylakoid lumen [GO:0031977]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1y0od__d2pv2c___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast thylakoid lumen [GO:0009543]; plastid [GO:0009536]; thylakoid lumen [GO:0031977]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	outer membrane-bounded periplasmic space [GO:0030288]; peptide binding [GO:0042277]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; chaperone cofactor-dependent protein refolding [GO:0051085]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; maintenance of stationary phase [GO:0060274]; protein folding [GO:0006457]; protein stabilization [GO:0050821]		chaperone cofactor-dependent protein refolding [GO:0051085]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; maintenance of stationary phase [GO:0060274]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	chloroplast [GO:0009507]; chloroplast thylakoid lumen [GO:0009543]; plastid [GO:0009536]; thylakoid lumen [GO:0031977]	outer membrane-bounded periplasmic space [GO:0030288]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptide binding [GO:0042277]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]
d1y0oe__d1hxva___1	Viridiplantae		Streptophyta	Tenericutes	chloroplast [GO:0009507]; chloroplast thylakoid lumen [GO:0009543]; plastid [GO:0009536]; thylakoid lumen [GO:0031977]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cytoplasm [GO:0005737]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; 'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]		'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]	chloroplast [GO:0009507]; chloroplast thylakoid lumen [GO:0009543]; plastid [GO:0009536]; thylakoid lumen [GO:0031977]	cytoplasm [GO:0005737]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]
d1y0oe__d5owib2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast thylakoid lumen [GO:0009543]; plastid [GO:0009536]; thylakoid lumen [GO:0031977]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; 'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]; response to heat [GO:0009408]		'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]; response to heat [GO:0009408]	chloroplast [GO:0009507]; chloroplast thylakoid lumen [GO:0009543]; plastid [GO:0009536]; thylakoid lumen [GO:0031977]	cytosol [GO:0005829]; membrane [GO:0016020]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]
d1y0pa3_d1lj1b3__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]	electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]	electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]
d1y0tb__d1c7da2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y0tc__d1mwba___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1y0td__d1c7cd___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y0vh1_d2lmva___1	Metazoa	Metazoa	Chordata	Arthropoda	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	cytoplasm [GO:0005737]; investment cone [GO:0070865]; myosin VI complex [GO:0031476]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; myosin VI head/neck binding [GO:0070855]; actin filament-based movement [GO:0030048]; calcium-mediated signaling [GO:0019722]	calcium-mediated signaling [GO:0019722]	actin filament-based movement [GO:0030048]; calcium-mediated signaling [GO:0019722]		cytoplasm [GO:0005737]; investment cone [GO:0070865]; myosin VI complex [GO:0031476]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; myosin VI head/neck binding [GO:0070855]
d1y0vj1_d3c1va___1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium-mediated signaling [GO:0019722]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]		collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d1y0vm1_d2ehba___1	Metazoa	Viridiplantae	Chordata	Streptophyta	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plant-type vacuole membrane [GO:0009705]; ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; response to salt stress [GO:0009651]	calcium-mediated signaling [GO:0019722]	intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]; nucleus [GO:0005634]; plant-type vacuole membrane [GO:0009705]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d1y0vm1_d4orbb___1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	calcineurin complex [GO:0005955]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynapse [GO:0098794]; sarcolemma [GO:0042383]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; calcium ion binding [GO:0005509]; cyclosporin A binding [GO:0016018]; enzyme binding [GO:0019899]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; protein domain specific binding [GO:0019904]; branching involved in blood vessel morphogenesis [GO:0001569]; calcineurin-NFAT signaling cascade [GO:0033173]; epithelial to mesenchymal transition [GO:0001837]; heart development [GO:0007507]; lung epithelial cell differentiation [GO:0060487]; myelination in peripheral nervous system [GO:0022011]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein dephosphorylation [GO:0006470]; protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; Schwann cell development [GO:0014044]	calcium-mediated signaling [GO:0019722]	branching involved in blood vessel morphogenesis [GO:0001569]; calcineurin-NFAT signaling cascade [GO:0033173]; epithelial to mesenchymal transition [GO:0001837]; heart development [GO:0007507]; lung epithelial cell differentiation [GO:0060487]; myelination in peripheral nervous system [GO:0022011]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein dephosphorylation [GO:0006470]; protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; Schwann cell development [GO:0014044]		calcineurin complex [GO:0005955]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynapse [GO:0098794]; sarcolemma [GO:0042383]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; cyclosporin A binding [GO:0016018]; enzyme binding [GO:0019899]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; protein domain specific binding [GO:0019904]
d1y0wa__d5nb3d___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1y0wb__d5x2ta___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y17a1_d4gj0d___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d1y17b__d1ptoi2__1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d1y18a1_d2r23b1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1y18a1_d4f33c1__1												
d1y18c1_d5fyke1__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d1y18c2_d3q6fe1__1												
d1y18d1_d2uylm1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1y18d2_d4gxvm2__1												
d1y18d2_d5j75a1__1												
d1y18f2_d3g6jg2__1		Metazoa		Chordata		azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]		amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]		azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]		C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d1y18l1_d1h3vb1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1y19d1_d2d10c1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d1y19f1_d1gg3c1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]
d1y19f1_d3wa0f2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d1y19h1_d4zrib2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]	actin binding [GO:0003779]
d1y19h2_d1gc6a2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d1y19h2_d5clld___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1y19j1_d3wa0e2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d1y1aa__d3nsoa1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; filopodium tip [GO:0032433]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; calcium-dependent protein kinase inhibitor activity [GO:0008427]; ion channel binding [GO:0044325]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein membrane anchor [GO:0043495]; protein serine/threonine kinase inhibitor activity [GO:0030291]; Ras GTPase binding [GO:0017016]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to growth factor stimulus [GO:0071363]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; cytoplasmic microtubule organization [GO:0031122]; double-strand break repair [GO:0006302]; endomitotic cell cycle [GO:0007113]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; platelet formation [GO:0030220]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of male germ cell proliferation [GO:2000256]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of cell division [GO:0051302]; regulation of cell population proliferation [GO:0042127]; response to ischemia [GO:0002931]; spermatid development [GO:0007286]; thrombopoietin-mediated signaling pathway [GO:0038163]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to growth factor stimulus [GO:0071363]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; cytoplasmic microtubule organization [GO:0031122]; double-strand break repair [GO:0006302]; endomitotic cell cycle [GO:0007113]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; platelet formation [GO:0030220]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of male germ cell proliferation [GO:2000256]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of cell division [GO:0051302]; regulation of cell population proliferation [GO:0042127]; response to ischemia [GO:0002931]; spermatid development [GO:0007286]; thrombopoietin-mediated signaling pathway [GO:0038163]		apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; filopodium tip [GO:0032433]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; vesicle [GO:0031982]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	calcium-dependent protein kinase inhibitor activity [GO:0008427]; calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein membrane anchor [GO:0043495]; protein serine/threonine kinase inhibitor activity [GO:0030291]; Ras GTPase binding [GO:0017016]	calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]
d1y1lb__d1d2ab___1		Fungi	Euryarchaeota	Ascomycota		cytoplasm [GO:0005737]; nucleus [GO:0005634]; acid phosphatase activity [GO:0003993]; protein tyrosine phosphatase activity [GO:0004725]; protein dephosphorylation [GO:0006470]		protein dephosphorylation [GO:0006470]		cytoplasm [GO:0005737]; nucleus [GO:0005634]		acid phosphatase activity [GO:0003993]; protein tyrosine phosphatase activity [GO:0004725]
d1y1lb__d3idob1__1			Euryarchaeota			protein tyrosine phosphatase activity [GO:0004725]						protein tyrosine phosphatase activity [GO:0004725]
d1y1lc__d2cwda___1			Euryarchaeota	Deinococcus-Thermus		protein tyrosine phosphatase activity [GO:0004725]						protein tyrosine phosphatase activity [GO:0004725]
d1y1ld__d2wmya___1			Euryarchaeota	Proteobacteria		protein tyrosine phosphatase activity [GO:0004725]						protein tyrosine phosphatase activity [GO:0004725]
d1y1pb__d1o0sb1__1	Fungi	Metazoa	Basidiomycota	Nematoda (roundworms)	alcohol dehydrogenase (NADP+) activity [GO:0008106]; coenzyme binding [GO:0050662]	mitochondrial matrix [GO:0005759]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]				mitochondrial matrix [GO:0005759]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; coenzyme binding [GO:0050662]	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]
d1y1sc__d5mx4f___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	purine nucleoside metabolic process [GO:0042278]	cytoplasm [GO:0005737]		uridine phosphorylase activity [GO:0004850]	purine-nucleoside phosphorylase activity [GO:0004731]
d1y1se__d1jdvc___1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]		uridine phosphorylase activity [GO:0004850]	S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]
d1y1ta__d4h1tf___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	uridine phosphorylase activity [GO:0004850]	metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]
d1y22d__d1hlba___1	Metazoa	Metazoa	Chordata	Echinodermata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y23a__d1gupa1__1			Firmicutes	Proteobacteria	catalytic activity [GO:0003824]; nucleotide metabolic process [GO:0009117]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; galactose catabolic process via UDP-galactose [GO:0033499]	nucleotide metabolic process [GO:0009117]	galactose catabolic process via UDP-galactose [GO:0033499]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	catalytic activity [GO:0003824]	ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]
d1y23c__d1zwja2__1		Viridiplantae	Firmicutes	Streptophyta	catalytic activity [GO:0003824]; nucleotide metabolic process [GO:0009117]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	nucleotide metabolic process [GO:0009117]	carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]			catalytic activity [GO:0003824]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]
d1y23c__d5km0a___1		Metazoa	Firmicutes	Chordata	catalytic activity [GO:0003824]; nucleotide metabolic process [GO:0009117]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	nucleotide metabolic process [GO:0009117]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d1y23d__d2h39a2__1		Viridiplantae	Firmicutes	Streptophyta	catalytic activity [GO:0003824]; nucleotide metabolic process [GO:0009117]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	nucleotide metabolic process [GO:0009117]	carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]			catalytic activity [GO:0003824]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]
d1y23d__d5km3a___1		Metazoa	Firmicutes	Chordata	catalytic activity [GO:0003824]; nucleotide metabolic process [GO:0009117]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	nucleotide metabolic process [GO:0009117]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d1y2da__d2gz4a1__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]		adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]		apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]		3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	
d1y2ga__d1s1ja___1			Proteobacteria	Proteobacteria	cell division site [GO:0032153]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]	cell division site [GO:0032153]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]	division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]	division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]	cell division site [GO:0032153]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell division site [GO:0032153]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		
d1y2tb__d3qduc___1	Fungi	Fungi	Basidiomycota	Basidiomycota	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d1y2ua__d1kd6a___1	Fungi	Metazoa	Basidiomycota	Cnidaria	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]	carbohydrate binding [GO:0030246]	channel activity [GO:0015267]; toxin activity [GO:0090729]
d1y2ub__d1tzqa___1	Fungi	Metazoa	Basidiomycota	Cnidaria	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]	carbohydrate binding [GO:0030246]	channel activity [GO:0015267]; toxin activity [GO:0090729]
d1y2vb__d4z2qb___1	Fungi	Fungi	Basidiomycota	Basidiomycota	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d1y2wb__d1o71a___1	Fungi	Metazoa	Basidiomycota	Cnidaria	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]	carbohydrate binding [GO:0030246]	channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]
d1y2xb__d1iaza___1	Fungi	Metazoa	Basidiomycota	Cnidaria	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]	carbohydrate binding [GO:0030246]	channel activity [GO:0015267]; toxin activity [GO:0090729]
d1y2xb__d1xi0b___1	Fungi	Fungi	Basidiomycota	Basidiomycota	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d1y2za__d3wcug___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y2zd__d1r1xb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y30a1_d5chod___1			Actinobacteria		coenzyme F420 binding [GO:0070967]; FMN binding [GO:0010181]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; vitamin B6 metabolic process [GO:0042816]	FMN binding [GO:0010181]	vitamin B6 metabolic process [GO:0042816]				coenzyme F420 binding [GO:0070967]; FMN binding [GO:0010181]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]	FMN binding [GO:0010181]
d1y31a__d3bj3a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y31c__d1o1pa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y34e2_d1zvja___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1y34i1_d1mita___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	serine-type endopeptidase inhibitor activity [GO:0004867]; response to wounding [GO:0009611]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	response to wounding [GO:0009611]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1y35d__d2uunw___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1y37b__d3kwhb2__1			Proteobacteria		haloacetate dehalogenase activity [GO:0018785]						haloacetate dehalogenase activity [GO:0018785]	
d1y38b__d5tfvb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d1y3be2_d3i30x___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1y3ja1_d4a46d___1	Metazoa		Chordata	Cyanobacteria	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]; antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	copper ion binding [GO:0005507]; metal ion transport [GO:0030001]	antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	metal ion transport [GO:0030001]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]	copper ion binding [GO:0005507]
d1y3pa__d4o3ab1__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d1y41a1_d1hxrb___1		Metazoa		Chordata		cytosol [GO:0005829]; membrane [GO:0016020]; guanyl-nucleotide exchange factor activity [GO:0005085]; zinc ion binding [GO:0008270]; post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]		post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]		cytosol [GO:0005829]; membrane [GO:0016020]		guanyl-nucleotide exchange factor activity [GO:0005085]; zinc ion binding [GO:0008270]
d1y43.1_d1redb1__1	Fungi	Fungi	Ascomycota	Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]	endo-1,4-beta-xylanase activity [GO:0031176]
d1y48i1_d1lw6i___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1y4ba__d2uulx___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1y4ca1_d4pfyb1__1			Proteobacteria	Thermotogae	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; metal ion binding [GO:0046872]; peptide transmembrane transporter activity [GO:1904680]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	metal ion binding [GO:0046872]; peptide transmembrane transporter activity [GO:1904680]
d1y4ca1_d5neba1__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d1y4di__d1y3ci1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1y4fa__d2gkna___1	Metazoa		Chordata	Actinobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d1y4fd__d1gh0m___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1y4ka1_d1fgta1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]; oxylipin biosynthetic process [GO:0031408]	cytoplasm [GO:0005737]; linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]; oxylipin biosynthetic process [GO:0031408]	oxylipin biosynthetic process [GO:0031408]	oxylipin biosynthetic process [GO:0031408]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]	linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]
d1y4ob2_d5y39h___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; microtubule [GO:0005874]; dynein intermediate chain binding [GO:0045505]; identical protein binding [GO:0042802]; motor activity [GO:0003774]; microtubule-based movement [GO:0007018]; visual behavior [GO:0007632]	endosome membrane [GO:0010008]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; Ragulator complex [GO:0071986]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; guanyl-nucleotide exchange factor activity [GO:0005085]; molecular adaptor activity [GO:0060090]; activation of MAPKK activity [GO:0000186]; cell cycle arrest [GO:0007050]; cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; MAPK cascade [GO:0000165]; neutrophil degranulation [GO:0043312]; positive regulation of TOR signaling [GO:0032008]; regulation of cell growth [GO:0001558]; regulation of macroautophagy [GO:0016241]	microtubule-based movement [GO:0007018]; visual behavior [GO:0007632]	activation of MAPKK activity [GO:0000186]; cell cycle arrest [GO:0007050]; cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; MAPK cascade [GO:0000165]; neutrophil degranulation [GO:0043312]; positive regulation of TOR signaling [GO:0032008]; regulation of cell growth [GO:0001558]; regulation of macroautophagy [GO:0016241]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; microtubule [GO:0005874]	endosome membrane [GO:0010008]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; Ragulator complex [GO:0071986]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	dynein intermediate chain binding [GO:0045505]; identical protein binding [GO:0042802]; motor activity [GO:0003774]	guanyl-nucleotide exchange factor activity [GO:0005085]; molecular adaptor activity [GO:0060090]
d1y4pc__d1ecaa___1	Metazoa	Metazoa	Chordata	Arthropoda	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y4pd__d5lkva___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d1y4qb__d3l0fa___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1y4qb__d3uhib___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y4qd__d4l2ma___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y4ra__d3o2ca___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1y4rd__d3wyob___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y4td__d4pddc1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	outer membrane-bounded periplasmic space [GO:0030288]; transmembrane transport [GO:0055085]		transmembrane transport [GO:0055085]		outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]	
d1y4va__d3pt7a___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y4wa1_d5kxec___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; fructan beta-fructosidase activity [GO:0051669]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]	polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		fructan beta-fructosidase activity [GO:0051669]	carbohydrate binding [GO:0030246]
d1y4yc__d3lfga___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]		transferase activity [GO:0016740]
d1y51b__d3le1b___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]		transferase activity [GO:0016740]
d1y52y1_d3wzqb1__1	Metazoa		Chordata	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d1y59t__d4nsyb___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type peptidase activity [GO:0008236]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type peptidase activity [GO:0008236]
d1y5fa__d2mgma___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y5fd__d3ozva1__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y5ia1_d4kodf1__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d1y5ia2_d1ti2g2__1			Proteobacteria		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]	
d1y5ib__d1ti4j2__1			Proteobacteria		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]	
d1y5jb__d2zs0b___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y5ka__d1binb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; nodulation [GO:0009877]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	nodulation [GO:0009877]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y5ka__d5nb4k___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1y5kd__d1gbub___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y5kd__d5aqdd___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1y5oa1_d1plsa1__1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]; nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]; actin cytoskeleton reorganization [GO:0031532]; cell projection organization [GO:0030030]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G protein-coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin-activated receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904]	nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	actin cytoskeleton reorganization [GO:0031532]; cell projection organization [GO:0030030]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G protein-coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin-activated receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904]	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]	phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]
d1y5ra__d4fccj2__1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]	cellular amino acid metabolic process [GO:0006520]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1y5rb__d1jw7c___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]		glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]	
d1y5rb__d4wasa2__1	Metazoa	Fungi	Chordata	Ascomycota	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]	mitochondrion [GO:0005739]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]	trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]
d1y5yd__d2gq0a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; carbon-nitrogen lyase activity [GO:0016840]; carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; cellular response to DNA damage stimulus [GO:0006974]; protein folding [GO:0006457]; response to heat [GO:0009408]	carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	cellular response to DNA damage stimulus [GO:0006974]; protein folding [GO:0006457]; response to heat [GO:0009408]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	carbon-nitrogen lyase activity [GO:0016840]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]
d1y5ye__d4jg4a___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; carbon-nitrogen lyase activity [GO:0016840]; carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	ribonuclease P complex [GO:0030677]; 3'-tRNA processing endoribonuclease activity [GO:0042781]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; phosphate ion binding [GO:0042301]; ribonuclease P activity [GO:0004526]; ribonuclease P RNA binding [GO:0033204]; sulfate binding [GO:0043199]; tRNA binding [GO:0000049]; tRNA 3'-trailer cleavage, endonucleolytic [GO:0034414]; tRNA 5'-leader removal [GO:0001682]	carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	tRNA 3'-trailer cleavage, endonucleolytic [GO:0034414]; tRNA 5'-leader removal [GO:0001682]	cytoplasm [GO:0005737]	ribonuclease P complex [GO:0030677]	carbon-nitrogen lyase activity [GO:0016840]	3'-tRNA processing endoribonuclease activity [GO:0042781]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; phosphate ion binding [GO:0042301]; ribonuclease P activity [GO:0004526]; ribonuclease P RNA binding [GO:0033204]; sulfate binding [GO:0043199]; tRNA binding [GO:0000049]
d1y60a__d4u3ba1__1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; carbon-nitrogen lyase activity [GO:0016840]; carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]		carbon-nitrogen lyase activity [GO:0016840]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d1y60b__d3wu4c___1			Proteobacteria		cytoplasm [GO:0005737]; carbon-nitrogen lyase activity [GO:0016840]; carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]		carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]		cytoplasm [GO:0005737]		carbon-nitrogen lyase activity [GO:0016840]	
d1y67a2_d3ak1c2__1			Deinococcus-Thermus	Crenarchaeota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1y67b1_d4f2nc1__1			Deinococcus-Thermus		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1y67b2_d1bs3b2__1			Deinococcus-Thermus	Actinobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1y67c1_d4yipb1__1			Deinococcus-Thermus	Firmicutes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1y67d1_d1en4c1__1			Deinococcus-Thermus	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1y6ea2_d3gfka___1	Metazoa		Platyhelminthes	Firmicutes	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]; transcription, DNA-templated [GO:0006351]		transcription, DNA-templated [GO:0006351]		cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]
d1y6hb__d2os3a1__1			Spirochaetes	Firmicutes	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	translation [GO:0006412]			metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d1y6kr1_d1mfna2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]; aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; mercury ion binding [GO:0045340]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell activation [GO:0001775]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell-substrate junction assembly [GO:0007044]; cellular response to interleukin-1 [GO:0071347]; cellular response to mercury ion [GO:0071288]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; glial cell migration [GO:0008347]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; positive regulation of axon extension [GO:0045773]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell activation [GO:0001775]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell-substrate junction assembly [GO:0007044]; cellular response to interleukin-1 [GO:0071347]; cellular response to mercury ion [GO:0071288]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; glial cell migration [GO:0008347]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; positive regulation of axon extension [GO:0045773]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]	chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; mercury ion binding [GO:0045340]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]
d1y6ml__d4ypgd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; interleukin-10 binding [GO:0019969]; interleukin-10 receptor activity [GO:0004920]; signaling receptor activity [GO:0038023]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of autophagy [GO:0010507]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of synapse organization [GO:0050807]; response to lipopolysaccharide [GO:0032496]; ubiquitin-dependent endocytosis [GO:0070086]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	cytokine-mediated signaling pathway [GO:0019221]; negative regulation of autophagy [GO:0010507]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of synapse organization [GO:0050807]; response to lipopolysaccharide [GO:0032496]; ubiquitin-dependent endocytosis [GO:0070086]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine receptor activity [GO:0004896]; interleukin-10 binding [GO:0019969]; interleukin-10 receptor activity [GO:0004920]; signaling receptor activity [GO:0038023]	cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]
d1y7ab__d1kh9b___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d1y7ba1_d2exkb1__1			Firmicutes	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1y7ba2_d3byja___1			Firmicutes	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; levansucrase activity [GO:0050053]; carbohydrate utilization [GO:0009758]	carbohydrate metabolic process [GO:0005975]	carbohydrate utilization [GO:0009758]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	levansucrase activity [GO:0050053]
d1y7bb1_d3ayea1__1		Metazoa	Firmicutes	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	carbohydrate metabolic process [GO:0005975]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d1y7bc1_d1lhoa___1		Metazoa	Firmicutes	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; androgen binding [GO:0005497]; steroid binding [GO:0005496]	carbohydrate metabolic process [GO:0005975]			extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	androgen binding [GO:0005497]; steroid binding [GO:0005496]
d1y7bc2_d4udkb___1			Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	
d1y7cd__d4wjgz___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y7gd__d1xzua___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y7na1_d4nmob___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; amyloid-beta binding [GO:0001540]; axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; intracellular protein transport [GO:0006886]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	amyloid-beta binding [GO:0001540]	ion channel binding [GO:0044325]
d1y7pb2_d2wvdd2__1			Euryarchaeota	Proteobacteria		protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]		negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]		protein-DNA complex [GO:0032993]		DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1y7pc1_d3ffta___1			Euryarchaeota	Proteobacteria		cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d1y7tb2_d2zqze2__1			Deinococcus-Thermus	Firmicutes	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d1y7ya1_d2bnnb1__1			Proteobacteria	Actinobacteria	DNA binding [GO:0003677]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]			DNA binding [GO:0003677]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d1y7za__d1a3nb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y7zb__d3ciud1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y83d__d2uunj___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1y85b__d4dwta___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d1y8ha__d3wfua___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y8ia__d1cg5b___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y8id__d2g0za___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y8ka__d3a2ga___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y8kb__d5mjda___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y8rc__d2qhog___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; SUMO activating enzyme complex [GO:0031510]; ATP binding [GO:0005524]; enzyme activator activity [GO:0008047]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; small protein activating enzyme binding [GO:0044388]; SUMO activating enzyme activity [GO:0019948]; SUMO binding [GO:0032183]; transcription factor binding [GO:0008134]; transferase activity [GO:0016740]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; protein modification by small protein conjugation [GO:0032446]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	protein modification by small protein conjugation [GO:0032446]; protein sumoylation [GO:0016925]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; SUMO activating enzyme complex [GO:0031510]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; enzyme activator activity [GO:0008047]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; small protein activating enzyme binding [GO:0044388]; SUMO activating enzyme activity [GO:0019948]; SUMO binding [GO:0032183]; transcription factor binding [GO:0008134]; transferase activity [GO:0016740]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1y8wa__d2vjra___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1y8wb__d1ymaa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1y9da3_d2wvhx1__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1y9db3_d4zp1a3__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1y9dd3_d1ozhb3__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; butanediol metabolic process [GO:0034077]		butanediol metabolic process [GO:0034077]			magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1y9ga1_d1leca___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; fructan beta-fructosidase activity [GO:0051669]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		fructan beta-fructosidase activity [GO:0051669]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1y9ma1_d1q2ba___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; fructan beta-fructosidase activity [GO:0051669]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	fructan beta-fructosidase activity [GO:0051669]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d1y9ma2_d1w2tb2__1	Fungi		Ascomycota	Thermotogae	extracellular region [GO:0005576]; fructan beta-fructosidase activity [GO:0051669]; polysaccharide catabolic process [GO:0000272]	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		fructan beta-fructosidase activity [GO:0051669]	beta-fructofuranosidase activity [GO:0004564]
d1y9wa1_d1yk3a1__1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; N-acetyltransferase activity [GO:0008080]	acyl-CoA hydrolase activity [GO:0047617]; N-acyltransferase activity [GO:0016410]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; siderophore biosynthetic process from catechol [GO:0019540]		siderophore biosynthetic process from catechol [GO:0019540]	cytoplasm [GO:0005737]		N-acetyltransferase activity [GO:0008080]	acyl-CoA hydrolase activity [GO:0047617]; N-acyltransferase activity [GO:0016410]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1y9wa1_d4jlyd___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; N-acetyltransferase activity [GO:0008080]	cytoplasm [GO:0005737]; diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]; polyamine catabolic process [GO:0006598]		polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	N-acetyltransferase activity [GO:0008080]	diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]
d1y9xa__d2z7cb___1			Crenarchaeota	Euryarchaeota	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]; chromosome condensation [GO:0030261]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	chromosome condensation [GO:0030261]		chromosome [GO:0005694]; cytoplasm [GO:0005737]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]
d1ya4a1_d1cuea___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	cutinase activity [GO:0050525]
d1ya4b1_d3fyte___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	acetylesterase activity [GO:0008126]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]		carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	acetylesterase activity [GO:0008126]
d1ya5a1_d4aizd___1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	extracellular region [GO:0005576]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	extracellular region [GO:0005576]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	
d1ya5a1_d4pjcg2__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ya5a2_d5hy9a1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ya5b1_d2qqkl1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ya5b2_d4np4l1__1	Metazoa		Chordata	Firmicutes	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	host cell plasma membrane [GO:0020002]; cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	pathogenesis [GO:0009405]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	host cell plasma membrane [GO:0020002]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]
d1ya7c__d5bouh___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ya7h__d5cgfi___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1ya8a__d4dmkb1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	hydrolase activity [GO:0016787]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]		carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	hydrolase activity [GO:0016787]
d1ya8b__d3qmma___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	lipid catabolic process [GO:0016042]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d1yaac__d2bwoe___1	Fungi		Ascomycota	Proteobacteria	cytosol [GO:0005829]; peroxisome [GO:0005777]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; asparagine biosynthetic process from oxaloacetate [GO:0019266]; aspartate biosynthetic process [GO:0006532]; aspartate metabolic process [GO:0006531]; glutamate metabolic process [GO:0006536]	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]; protoporphyrinogen IX biosynthetic process [GO:0006782]	2-oxoglutarate metabolic process [GO:0006103]; asparagine biosynthetic process from oxaloacetate [GO:0019266]; aspartate biosynthetic process [GO:0006532]; aspartate metabolic process [GO:0006531]; glutamate metabolic process [GO:0006536]	protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]; peroxisome [GO:0005777]		L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]
d1yabb1_d1o9yd___1			Thermotogae	Proteobacteria	bacterial-type flagellum basal body [GO:0009425]; membrane [GO:0016020]; motor activity [GO:0003774]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]	bacterial-type flagellum basal body [GO:0009425]; cytoplasm [GO:0005737]; motor activity [GO:0003774]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; pathogenesis [GO:0009405]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; pathogenesis [GO:0009405]	bacterial-type flagellum basal body [GO:0009425]; membrane [GO:0016020]	bacterial-type flagellum basal body [GO:0009425]; cytoplasm [GO:0005737]	motor activity [GO:0003774]	motor activity [GO:0003774]
d1yaca__d3r2jd___1			Proteobacteria		cytosol [GO:0005829]; membrane [GO:0016020]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]			cytosol [GO:0005829]; membrane [GO:0016020]		hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1yafa__d1ni6d___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; thiaminase activity [GO:0050334]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cytosol [GO:0005829]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	thiaminase activity [GO:0050334]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1yafb__d4wd4c___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; thiaminase activity [GO:0050334]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cytosol [GO:0005829]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	thiaminase activity [GO:0050334]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d1yafc__d1wzda___1			Firmicutes	Actinobacteria	cytosol [GO:0005829]; thiaminase activity [GO:0050334]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	heme oxidation [GO:0006788]	cytosol [GO:0005829]		thiaminase activity [GO:0050334]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d1yaga1_d5ex5a1__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1yagg__d2hd7a1__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; filopodium [GO:0030175]; myofibril [GO:0030016]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; actin filament depolymerization [GO:0030042]; barbed-end actin filament capping [GO:0051016]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of neuron projection development [GO:0010976]; regulation of actin phosphorylation [GO:0043538]; regulation of lamellipodium assembly [GO:0010591]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament depolymerization [GO:0030042]; barbed-end actin filament capping [GO:0051016]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of neuron projection development [GO:0010976]; regulation of actin phosphorylation [GO:0043538]; regulation of lamellipodium assembly [GO:0010591]; sequestering of actin monomers [GO:0042989]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; filopodium [GO:0030175]; myofibril [GO:0030016]; perinuclear region of cytoplasm [GO:0048471]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]
d1yaha__d2g63a2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d1yahb__d3fcyb___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]		carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d1yaic__d2aqrc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]
d1yaja1_d3zv7a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	acetylcholinesterase activity [GO:0003990]
d1yajb1_d3w9ba___1	Metazoa	Fungi	Chordata	Basidiomycota	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	lipid catabolic process [GO:0016042]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]		carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	triglyceride lipase activity [GO:0004806]
d1yajf1_d3dd5d___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]; pathogenesis [GO:0009405]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	pathogenesis [GO:0009405]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	cutinase activity [GO:0050525]
d1yajg1_d4oyyj___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	cutinase activity [GO:0050525]
d1yajj1_d2vt6b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	acetylcholinesterase activity [GO:0003990]
d1yama__d3tmua___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1yana__d1tewa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1yana__d235la___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1yaqa__d1qswd___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1yarb__d3sdiv___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1yard__d3wxrf___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1yarf__d3okjw___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1yarj__d5l55y___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1yarl__d5m2bu___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1yarn__d5dkiv___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1yata__d4jfja1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; chromatin organization [GO:0006325]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of homoserine biosynthetic process [GO:1901710]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	chaperone-mediated protein folding [GO:0061077]; chromatin organization [GO:0006325]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of homoserine biosynthetic process [GO:1901710]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d1yaua__d4qv4q___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1yaua__d5l5jb___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1yaud__d4wl3b___1				Firmicutes	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	hydrolase activity [GO:0016787]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]		proteasome activator complex [GO:0008537]			hydrolase activity [GO:0016787]
d1yaug__d5l54v___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1yb5a2_d3tzqg___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mRNA 3'-UTR binding [GO:0003730]; NADPH binding [GO:0070402]; NADPH:quinone reductase activity [GO:0003960]; zinc ion binding [GO:0008270]; protein homotetramerization [GO:0051289]; visual perception [GO:0007601]; xenobiotic catabolic process [GO:0042178]		protein homotetramerization [GO:0051289]; visual perception [GO:0007601]; xenobiotic catabolic process [GO:0042178]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		mRNA 3'-UTR binding [GO:0003730]; NADPH:quinone reductase activity [GO:0003960]; NADPH binding [GO:0070402]; zinc ion binding [GO:0008270]	
d1yb5b2_d1lssb___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mRNA 3'-UTR binding [GO:0003730]; NADPH binding [GO:0070402]; NADPH:quinone reductase activity [GO:0003960]; zinc ion binding [GO:0008270]; protein homotetramerization [GO:0051289]; visual perception [GO:0007601]; xenobiotic catabolic process [GO:0042178]	plasma membrane [GO:0005886]; potassium ion transmembrane transporter activity [GO:0015079]	protein homotetramerization [GO:0051289]; visual perception [GO:0007601]; xenobiotic catabolic process [GO:0042178]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	plasma membrane [GO:0005886]	mRNA 3'-UTR binding [GO:0003730]; NADPH:quinone reductase activity [GO:0003960]; NADPH binding [GO:0070402]; zinc ion binding [GO:0008270]	potassium ion transmembrane transporter activity [GO:0015079]
d1yb6a__d5egnc___1	Viridiplantae		Streptophyta		aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	methyl indole-3-acetate esterase activity [GO:0080030]					aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	methyl indole-3-acetate esterase activity [GO:0080030]
d1ybha2_d1zpdb2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1ybia1_d3w9td2__1		Metazoa	Firmicutes	Echinodermata		carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]						carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1ybib2_d5gqdb2__1			Firmicutes	Actinobacteria		endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]				endo-1,4-beta-xylanase activity [GO:0031176]
d1ybja__d4jetd___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1yboa1_d3rl8e___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; costamere [GO:0043034]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; lysosomal lumen [GO:0043202]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; protein kinase C binding [GO:0005080]; thrombospondin receptor activity [GO:0070053]; cell migration [GO:0016477]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell stereocilium organization [GO:0060122]; leukocyte migration [GO:0050900]; negative regulation of T cell proliferation [GO:0042130]; neural tube closure [GO:0001843]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of stress fiber assembly [GO:0051496]; regulation of fibroblast migration [GO:0010762]; retinoid metabolic process [GO:0001523]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]	adherens junction [GO:0005912]; beta-catenin destruction complex [GO:0030877]; bicellular tight junction [GO:0005923]; catenin complex [GO:0016342]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; Wnt signalosome [GO:1990909]; beta-catenin binding [GO:0008013]; dynein complex binding [GO:0070840]; gamma-catenin binding [GO:0045295]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin protein ligase binding [GO:0031625]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; insulin receptor signaling pathway [GO:0008286]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of microtubule depolymerization [GO:0007026]; pattern specification process [GO:0007389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration [GO:0030335]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of pseudopodium assembly [GO:0031274]; protein deubiquitination [GO:0016579]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell differentiation [GO:0045595]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055]	cell migration [GO:0016477]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell stereocilium organization [GO:0060122]; leukocyte migration [GO:0050900]; negative regulation of T cell proliferation [GO:0042130]; neural tube closure [GO:0001843]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of stress fiber assembly [GO:0051496]; regulation of fibroblast migration [GO:0010762]; retinoid metabolic process [GO:0001523]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]	beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; insulin receptor signaling pathway [GO:0008286]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of microtubule depolymerization [GO:0007026]; pattern specification process [GO:0007389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration [GO:0030335]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of pseudopodium assembly [GO:0031274]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homooligomerization [GO:0051260]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell differentiation [GO:0045595]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055]	cell surface [GO:0009986]; costamere [GO:0043034]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; lysosomal lumen [GO:0043202]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	adherens junction [GO:0005912]; beta-catenin destruction complex [GO:0030877]; bicellular tight junction [GO:0005923]; catenin complex [GO:0016342]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; Wnt signalosome [GO:1990909]	fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; protein kinase C binding [GO:0005080]; thrombospondin receptor activity [GO:0070053]	beta-catenin binding [GO:0008013]; dynein complex binding [GO:0070840]; gamma-catenin binding [GO:0045295]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin protein ligase binding [GO:0031625]
d1ybob1_d1n6fd1__1	Metazoa		Chordata	Euryarchaeota	cell surface [GO:0009986]; costamere [GO:0043034]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; lysosomal lumen [GO:0043202]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; protein kinase C binding [GO:0005080]; thrombospondin receptor activity [GO:0070053]; cell migration [GO:0016477]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell stereocilium organization [GO:0060122]; leukocyte migration [GO:0050900]; negative regulation of T cell proliferation [GO:0042130]; neural tube closure [GO:0001843]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of stress fiber assembly [GO:0051496]; regulation of fibroblast migration [GO:0010762]; retinoid metabolic process [GO:0001523]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	cell migration [GO:0016477]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell stereocilium organization [GO:0060122]; leukocyte migration [GO:0050900]; negative regulation of T cell proliferation [GO:0042130]; neural tube closure [GO:0001843]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of stress fiber assembly [GO:0051496]; regulation of fibroblast migration [GO:0010762]; retinoid metabolic process [GO:0001523]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]	proteolysis [GO:0006508]	cell surface [GO:0009986]; costamere [GO:0043034]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; lysosomal lumen [GO:0043202]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; protein kinase C binding [GO:0005080]; thrombospondin receptor activity [GO:0070053]	serine-type peptidase activity [GO:0008236]
d1ybva__d2x86h___1	Fungi		Ascomycota	Proteobacteria	tetrahydroxynaphthalene reductase activity [GO:0047039]; melanin biosynthetic process [GO:0042438]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	melanin biosynthetic process [GO:0042438]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]			tetrahydroxynaphthalene reductase activity [GO:0047039]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]
d1ybvb__d2wyuc___1	Fungi		Ascomycota	Deinococcus-Thermus	tetrahydroxynaphthalene reductase activity [GO:0047039]; melanin biosynthetic process [GO:0042438]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	melanin biosynthetic process [GO:0042438]	fatty acid biosynthetic process [GO:0006633]			tetrahydroxynaphthalene reductase activity [GO:0047039]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d1ybza1_d5ts9c___1			Euryarchaeota	Proteobacteria	chorismate mutase activity [GO:0004106]; chorismate metabolic process [GO:0046417]	chorismate metabolic process [GO:0046417]	chorismate metabolic process [GO:0046417]	chorismate metabolic process [GO:0046417]			chorismate mutase activity [GO:0004106]	
d1yc2b__d4k9ka2__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]		NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1yc2c__d2ez8b1__1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]			cytoplasm [GO:0005737]		NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d1yc4a__d4xc0a___1	Metazoa		Chordata		axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; aggregation involved in sorocarp development [GO:0031152]; cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	aggregation involved in sorocarp development [GO:0031152]; cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d1yc61__d4rhv.1__1					host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1yc64__d1pov3___1					host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1yc6d__d1js9c___1					host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]			host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1yc6i__d4pdwa___1					host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1yc6j__d1v9u3___1					host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1yc6n__d5w3la___1					host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]				host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]		RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	
d1yc6o__d1qjx1___1					host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1yc6t__d1rui1___1					host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1yc6u__d1rug1___1					host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1yc6v__d1ev13___1					host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d1yc6x__d5osna___1					host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]			host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	viral capsid [GO:0019028]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d1ycaa__d2vmlc___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1ycfa1_d5eain___1		Metazoa	Firmicutes	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d1ycfd1_d3gfsi___1			Firmicutes	Firmicutes	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]				cytosol [GO:0005829]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d1ycga1_d1dxoa___1		Metazoa	Firmicutes	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d1ycgb1_d1e5da1__1			Firmicutes	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; respiratory electron transport chain [GO:0022904]		respiratory electron transport chain [GO:0022904]			electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1ycgb1_d2qwxb___1		Metazoa	Firmicutes	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1ycgc2_d4pvta___1			Firmicutes	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1ycha1_d2bmva___1			Firmicutes	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	FMN binding [GO:0010181]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]			electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	FMN binding [GO:0010181]
d1ycha1_d3tzbc1__1		Metazoa	Firmicutes	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1ychb1_d3nhfa___1		Metazoa	Firmicutes	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1ychc1_d1bu5b___1			Firmicutes	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1ychc1_d3f90e___1			Firmicutes	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1ycla__d1ntka2__1		Metazoa	Firmicutes	Chordata	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]; quorum sensing [GO:0009372]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	quorum sensing [GO:0009372]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1ycma2_d5d7wa1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; pathogenesis [GO:0009405]; proteolysis [GO:0006508]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	pathogenesis [GO:0009405]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1ycqa__d3dabg1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; metal ion binding [GO:0046872]; transferase activity [GO:0016740]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein ubiquitination [GO:0016567]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein ubiquitination [GO:0016567]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]
d1yd8u__d3sdld1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d1yd8v__d2rexa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116]; GTPase activating protein binding [GO:0032794]; GTPase activator activity [GO:0005096]; semaphorin receptor activity [GO:0017154]; semaphorin receptor binding [GO:0030215]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; cell migration [GO:0016477]; G protein-coupled receptor signaling pathway [GO:0007186]; inhibitory synapse assembly [GO:1904862]; intracellular signal transduction [GO:0035556]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220]; signal transduction [GO:0007165]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cell migration [GO:0016477]; G protein-coupled receptor signaling pathway [GO:0007186]; inhibitory synapse assembly [GO:1904862]; intracellular signal transduction [GO:0035556]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	GTPase activating protein binding [GO:0032794]; GTPase activator activity [GO:0005096]; semaphorin receptor activity [GO:0017154]; semaphorin receptor binding [GO:0030215]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]
d1yd9b__d1gyta1__1	Metazoa		Chordata	Proteobacteria	Barr body [GO:0001740]; chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	Barr body [GO:0001740]; chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]	aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]
d1ydea1_d1g1ad___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; NADH binding [GO:0070404]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	cytosol [GO:0005829]		estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; NADH binding [GO:0070404]
d1ydec__d1kc1a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	cytosol [GO:0005829]; dTDP-4-dehydrorhamnose reductase activity [GO:0008831]; metal ion binding [GO:0046872]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	cytosol [GO:0005829]	cytosol [GO:0005829]	estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]	dTDP-4-dehydrorhamnose reductase activity [GO:0008831]; metal ion binding [GO:0046872]
d1ydef__d1ldga1__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytosol [GO:0005829]		estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]	L-lactate dehydrogenase activity [GO:0004459]
d1ydeh__d4b8za___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]	coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]
d1ydgd1_d2ohhe2__1			Deinococcus-Thermus	Euryarchaeota	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidation-reduction process [GO:0055114]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	oxidation-reduction process [GO:0055114]				FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1ydge1_d3ox2b___1		Metazoa	Deinococcus-Thermus	Chordata	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1ydgf1_d3ox1b___1		Metazoa	Deinococcus-Thermus	Chordata	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d1ydgh1_d3f90g___1			Deinococcus-Thermus	Proteobacteria	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidation-reduction process [GO:0055114]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	oxidation-reduction process [GO:0055114]				FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d1ydka1_d2v6ka2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; maleylpyruvate isomerase activity [GO:0050077]; aromatic amino acid family metabolic process [GO:0009072]; aromatic compound catabolic process [GO:0019439]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	aromatic amino acid family metabolic process [GO:0009072]; aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	maleylpyruvate isomerase activity [GO:0050077]
d1ydkb1_d4f0ca2__1	Metazoa	Fungi	Chordata	Basidiomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	transferase activity [GO:0016740]
d1ydkb2_d5a5kc1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d1ydpa1_d5jdjp___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d1ydva__d2vfea___1			Apicomplexa	Apicomplexa	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]			identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]
d1ydvb__d4jeqd___1			Apicomplexa		identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]; glycosome [GO:0020015]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1ydzd__d2g0ra___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ydzd__d5b13b___1	Metazoa		Chordata	Rhodophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1ye0a__d1mdna___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ye0b__d1cohb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ye1b__d3bj1a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ye2a__d1y8hc___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ye2d__d1yhuv___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ye4c__d2bgsa___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	oxidoreductase activity [GO:0016491]; D-xylose catabolic process [GO:0042843]	alditol:NADP+ 1-oxidoreductase activity [GO:0004032]	D-xylose catabolic process [GO:0042843]				oxidoreductase activity [GO:0016491]	alditol:NADP+ 1-oxidoreductase activity [GO:0004032]
d1ye5a__d1v8pc1__1			Euryarchaeota	Crenarchaeota	magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]	exonuclease activity [GO:0004527]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]					magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]	exonuclease activity [GO:0004527]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]
d1yech1_d1akja1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1yech2_d3rtqc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1yecl1_d1blnb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yecl1_d5eiil2__1	Metazoa	Fungi	Chordata	Ascomycota	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleus [GO:0005634]; histone binding [GO:0042393]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H2B ubiquitination [GO:0033523]; nucleosome disassembly [GO:0006337]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of gene expression [GO:0010468]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H2B ubiquitination [GO:0033523]; nucleosome disassembly [GO:0006337]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of gene expression [GO:0010468]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleus [GO:0005634]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	histone binding [GO:0042393]
d1yecl2_d1xf2a2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1yecl2_d3fo9a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1yeda1_d1kxqe___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	carbohydrate catabolic process [GO:0016052]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1yeda2_d1t2ql1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	metal ion binding [GO:0046872]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d1yedb2_d3q5ta1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yedb2_d3stlb2__1	Metazoa		Chordata	Actinobacteria	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	voltage-gated potassium channel complex [GO:0008076]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1yedh1_d1igyb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1yedh2_d1qbll2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yedh2_d5e8eb2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d1yedl2_d4hcrn1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; integrin binding involved in cell-matrix adhesion [GO:0098640]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	integrin binding involved in cell-matrix adhesion [GO:0098640]
d1yeeh2_d2gfbe1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yeeh2_d4kklf2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1yeel2_d5sx5l1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d1yefh1_d4at6n1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yefl2_d1b2wh2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yegh2_d1rjla1__1	Metazoa		Chordata	Spirochaetes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell outer membrane [GO:0009279]; membrane [GO:0016020]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell outer membrane [GO:0009279]; membrane [GO:0016020]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yegl1_d1mjul2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yegl2_d4lcil___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yehl1_d1r3he1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1yeih1_d4xbgl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yeih2_d3cx5u___1	Metazoa	Fungi	Chordata	Ascomycota	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1yeil2_d3mnvc2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yejh2_d4k71e2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1yejl1_d4npyl2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yekh1_d4rfel1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yekh2_d5edxa___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	integral component of membrane [GO:0016021]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yekl1_d43c9c___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1yekl2_d3okoa2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1yemb1_d3n0za___1			Euryarchaeota	Proteobacteria		adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]						adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1yeob__d3uhsb___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yeob__d5aqda___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1yeod__d1x46a___1	Metazoa	Metazoa	Chordata	Arthropoda	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yepa__d1bq7a___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	thioredoxin peroxidase activity [GO:0008379]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d1yepb__d2xpdb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]	thioredoxin peroxidase activity [GO:0008379]	thioredoxin peroxidase activity [GO:0008379]
d1yepc__d2vm1d___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]	thioredoxin peroxidase activity [GO:0008379]	protein disulfide oxidoreductase activity [GO:0015035]
d1yepe__d3dwvb___1			Proteobacteria		cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	glycosome [GO:0020015]; glutathione peroxidase activity [GO:0004602]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]	glycosome [GO:0020015]	thioredoxin peroxidase activity [GO:0008379]	glutathione peroxidase activity [GO:0004602]
d1yeua__d5aqdk___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1yeud__d1o1od___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yexa1_d2lqoa1__1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]	thioredoxin peroxidase activity [GO:0008379]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d1yexc__d5jcgh1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; alkyl hydroperoxide reductase activity [GO:0008785]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	thioredoxin peroxidase activity [GO:0008379]	alkyl hydroperoxide reductase activity [GO:0008785]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d1yexd__d3zijb___1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]	thioredoxin peroxidase activity [GO:0008379]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d1yexe__d3a2va___1			Proteobacteria	Crenarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]	thioredoxin peroxidase activity [GO:0008379]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d1yf0a1_d3ljrb2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	thioredoxin peroxidase activity [GO:0008379]	glutathione transferase activity [GO:0004364]
d1yf0b__d5an1e1__1		Metazoa	Proteobacteria	Arthropoda	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cytosol [GO:0005829]		thioredoxin peroxidase activity [GO:0008379]	glutathione transferase activity [GO:0004364]
d1yf0c__d1sl1b___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	thioredoxin peroxidase activity [GO:0008379]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1yf0e__d3c7ma___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; periplasmic space [GO:0042597]	thioredoxin peroxidase activity [GO:0008379]	protein disulfide oxidoreductase activity [GO:0015035]
d1yf0e__d3tjbc___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	thioredoxin peroxidase activity [GO:0008379]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d1yf1d__d1guhb2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	thioredoxin peroxidase activity [GO:0008379]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1yf1e__d1tw9h2__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	transferase activity [GO:0016740]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cytosol [GO:0005829]		thioredoxin peroxidase activity [GO:0008379]	transferase activity [GO:0016740]
d1yf1f__d1zyna1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]	thioredoxin peroxidase activity [GO:0008379]	alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]
d1yf1j__d1grxa___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; electron transfer activity [GO:0009055]; nucleotide binding [GO:0000166]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]	thioredoxin peroxidase activity [GO:0008379]	electron transfer activity [GO:0009055]; nucleotide binding [GO:0000166]; protein disulfide oxidoreductase activity [GO:0015035]
d1yf4a__d2wpis___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]
d1yf8b1_d2d23b2__1	Viridiplantae		Streptophyta	Actinobacteria	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	endo-1,4-beta-xylanase activity [GO:0031176]
d1yf8b1_d2zqoa1__1	Viridiplantae	Metazoa	Streptophyta	Annelida	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	carbohydrate binding [GO:0030246]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]				carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]
d1yf9a1_d5d1la___1		Metazoa		Chordata	ATP binding [GO:0005524]; ligase activity [GO:0016874]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	ubiquitin-dependent protein catabolic process [GO:0006511]	cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; ubiquitin conjugating enzyme activity [GO:0061631]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]
d1yfdb__d3e1of___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1yffb__d1y7ca___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yffg__d2fama___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yfha1_d1sfea1__1	Metazoa		Chordata	Proteobacteria	membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; metal ion binding [GO:0046872]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; methyltransferase activity [GO:0008168]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of double-strand break repair [GO:2000781]	DNA-binding transcription factor activity [GO:0003700]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-cysteine methylation [GO:0018125]; positive regulation of transcription, DNA-templated [GO:0045893]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA ligation [GO:0006266]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of double-strand break repair [GO:2000781]	cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-cysteine methylation [GO:0018125]; positive regulation of transcription, DNA-templated [GO:0045893]	membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; metal ion binding [GO:0046872]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; methyltransferase activity [GO:0008168]	DNA-binding transcription factor activity [GO:0003700]; methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO:0003908]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d1yfib__d3v21e___1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	endonuclease activity [GO:0004519]	DNA restriction-modification system [GO:0009307]				DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]	endonuclease activity [GO:0004519]
d1yfkb__d3gw8b___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]		bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]
d1yfna__d2qazc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; ribosome [GO:0005840]; ATPase binding [GO:0051117]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; positive regulation of ATPase activity [GO:0032781]; positive regulation of protein catabolic process [GO:0045732]	identical protein binding [GO:0042802]	positive regulation of ATPase activity [GO:0032781]; positive regulation of protein catabolic process [GO:0045732]		cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; ribosome [GO:0005840]		ATPase binding [GO:0051117]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]	identical protein binding [GO:0042802]
d1yfsa2_d2djzb1__1			Aquificae	Euryarchaeota	cytosol [GO:0005829]; alanine-tRNA ligase activity [GO:0004813]; amino acid binding [GO:0016597]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; alanyl-tRNA aminoacylation [GO:0006419]; tRNA modification [GO:0006400]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	alanyl-tRNA aminoacylation [GO:0006419]; tRNA modification [GO:0006400]	cellular protein modification process [GO:0006464]	cytosol [GO:0005829]		alanine-tRNA ligase activity [GO:0004813]; amino acid binding [GO:0016597]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d1yfua1_d4uxap___1			Proteobacteria	Acidobacteria	3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]; 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]	metal ion binding [GO:0046872]	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]				3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]	metal ion binding [GO:0046872]
d1yfza1_d1oroa___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; orotate phosphoribosyltransferase activity [GO:0004588]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine nucleotide biosynthetic process [GO:0006221]; pyrimidine ribonucleoside biosynthetic process [GO:0046132]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine nucleotide biosynthetic process [GO:0006221]; pyrimidine ribonucleoside biosynthetic process [GO:0046132]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	magnesium ion binding [GO:0000287]; orotate phosphoribosyltransferase activity [GO:0004588]
d1yg5d__d3g4yb___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yg6b__d2zl4a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d1yg6b__d3mfmc2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	acetyl-CoA carboxylase complex [GO:0009317]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]
d1yg6c__d4i42a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; bicarbonate binding [GO:0071890]; menaquinone biosynthetic process [GO:0009234]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	menaquinone biosynthetic process [GO:0009234]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytosol [GO:0005829]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; bicarbonate binding [GO:0071890]
d1yg6d__d4qijh___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; 1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; menaquinone biosynthetic process [GO:0009234]; protein hexamerization [GO:0034214]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	menaquinone biosynthetic process [GO:0009234]; protein hexamerization [GO:0034214]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]
d1yg6k__d1o8uf___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]		ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]
d1yg6l__d3ktga1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]
d1yg8f__d4qijk___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; 1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; menaquinone biosynthetic process [GO:0009234]; protein hexamerization [GO:0034214]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	menaquinone biosynthetic process [GO:0009234]; protein hexamerization [GO:0034214]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]
d1yg8g__d1uyrb1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d1yg8m__d4ryfb___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d1yg8o__d3ktkn___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]
d1yg8p__d5ctcc1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d1yg8r__d2zl3d___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d1yg8s__d3r0ob___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	catalytic activity [GO:0003824]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]		ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	catalytic activity [GO:0003824]
d1yg8t__d1yg6h___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1yg8u__d3tz3a1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d1ygaa__d1so0a1__1	Fungi	Metazoa	Ascomycota	Chordata	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]	galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1ygda__d2zs1b___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ygea2_d1n8sa1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]; oxylipin biosynthetic process [GO:0031408]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; intestinal cholesterol absorption [GO:0030299]; lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241]; lipid metabolic process [GO:0006629]; positive regulation of triglyceride lipase activity [GO:0061365]; retinoid metabolic process [GO:0001523]	oxylipin biosynthetic process [GO:0031408]	intestinal cholesterol absorption [GO:0030299]; lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241]; lipid metabolic process [GO:0006629]; positive regulation of triglyceride lipase activity [GO:0061365]; retinoid metabolic process [GO:0001523]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]	lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d1ygfb__d3uhra___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ygfb__d5b13i___1	Metazoa		Chordata	Rhodophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1ygha__d5c88a1__1	Fungi		Ascomycota	Crenarchaeota	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; nucleus [GO:0005634]; SAGA complex [GO:0000124]; SLIK (SAGA-like) complex [GO:0046695]; H3 histone acetyltransferase activity [GO:0010484]; histone acetyltransferase activity [GO:0004402]; lysine-acetylated histone binding [GO:0070577]; transcription coactivator activity [GO:0003713]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; peptide alpha-N-acetyltransferase activity [GO:0004596]; N-terminal protein amino acid acetylation [GO:0006474]	chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]	N-terminal protein amino acid acetylation [GO:0006474]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; nucleus [GO:0005634]; SAGA complex [GO:0000124]; SLIK (SAGA-like) complex [GO:0046695]	cytoplasm [GO:0005737]	H3 histone acetyltransferase activity [GO:0010484]; histone acetyltransferase activity [GO:0004402]; lysine-acetylated histone binding [GO:0070577]; transcription coactivator activity [GO:0003713]	metal ion binding [GO:0046872]; peptide alpha-N-acetyltransferase activity [GO:0004596]
d1yghb__d1s60a1__1	Fungi		Ascomycota	Proteobacteria	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; nucleus [GO:0005634]; SAGA complex [GO:0000124]; SLIK (SAGA-like) complex [GO:0046695]; H3 histone acetyltransferase activity [GO:0010484]; histone acetyltransferase activity [GO:0004402]; lysine-acetylated histone binding [GO:0070577]; transcription coactivator activity [GO:0003713]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]; protein homodimerization activity [GO:0042803]; acetyl-CoA metabolic process [GO:0006084]; histone acetylation [GO:0016573]; response to antibiotic [GO:0046677]	chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]	acetyl-CoA metabolic process [GO:0006084]; histone acetylation [GO:0016573]; response to antibiotic [GO:0046677]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; nucleus [GO:0005634]; SAGA complex [GO:0000124]; SLIK (SAGA-like) complex [GO:0046695]		H3 histone acetyltransferase activity [GO:0010484]; histone acetyltransferase activity [GO:0004402]; lysine-acetylated histone binding [GO:0070577]; transcription coactivator activity [GO:0003713]	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]; protein homodimerization activity [GO:0042803]
d1ygka__d3rssa2__1	Metazoa		Chordata	Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]; pyridoxal 5'-phosphate salvage [GO:0009443]	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]; nicotinamide nucleotide metabolic process [GO:0046496]	pyridoxal 5'-phosphate salvage [GO:0009443]	nicotinamide nucleotide metabolic process [GO:0046496]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]
d1ygoa2_d2naqa___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; NLRP3 inflammasome complex [GO:0072559]; nucleus [GO:0005634]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; peptidoglycan binding [GO:0042834]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptidoglycan [GO:0071224]; cytokine secretion involved in immune response [GO:0002374]; defense response [GO:0006952]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta production [GO:0032611]; interleukin-1 secretion [GO:0050701]; interleukin-18 production [GO:0032621]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta secretion [GO:0050713]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein deubiquitination [GO:0016579]; signal transduction [GO:0007165]	antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptidoglycan [GO:0071224]; cytokine secretion involved in immune response [GO:0002374]; defense response [GO:0006952]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-18 production [GO:0032621]; interleukin-1 beta production [GO:0032611]; interleukin-1 secretion [GO:0050701]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta secretion [GO:0050713]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein deubiquitination [GO:0016579]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; NLRP3 inflammasome complex [GO:0072559]; nucleus [GO:0005634]	ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; peptidoglycan binding [GO:0042834]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d1yh2a1_d2edia1__1	Metazoa	Metazoa	Chordata	Chordata	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K6-linked ubiquitination [GO:0085020]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]	cytosol [GO:0005829]; ATP binding [GO:0005524]; NEDD8 conjugating enzyme activity [GO:0061654]; NEDD8 transferase activity [GO:0019788]; post-translational protein modification [GO:0043687]; protein neddylation [GO:0045116]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]	post-translational protein modification [GO:0043687]; protein neddylation [GO:0045116]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; NEDD8 conjugating enzyme activity [GO:0061654]; NEDD8 transferase activity [GO:0019788]
d1yh3b__d1ismb___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]; ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d1yh8b1_d1e3pa3__1			Aquificae	Actinobacteria	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; polyribonucleotide nucleotidyltransferase activity [GO:0004654]; RNA binding [GO:0003723]; mRNA catabolic process [GO:0006402]; RNA processing [GO:0006396]	lipid A biosynthetic process [GO:0009245]	mRNA catabolic process [GO:0006402]; RNA processing [GO:0006396]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]	magnesium ion binding [GO:0000287]; polyribonucleotide nucleotidyltransferase activity [GO:0004654]; RNA binding [GO:0003723]
d1yhba__d2gvbb___1					single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; rolling circle single-stranded viral DNA replication [GO:0039684]	single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; rolling circle single-stranded viral DNA replication [GO:0039684]	DNA replication [GO:0006260]; rolling circle single-stranded viral DNA replication [GO:0039684]	DNA replication [GO:0006260]; rolling circle single-stranded viral DNA replication [GO:0039684]			single-stranded DNA binding [GO:0003697]	single-stranded DNA binding [GO:0003697]
d1yhca2_d1n32e1__1			Aquificae	Deinococcus-Thermus	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	lipid A biosynthetic process [GO:0009245]	translation [GO:0006412]		ribosome [GO:0005840]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1yhoa__d2w9ha___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d1yhqe1_d1vq4e2__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1yhqf1_d1rlga___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; ribosome biogenesis [GO:0042254]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	translation [GO:0006412]	ribosome biogenesis [GO:0042254]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	ribosome [GO:0005840]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1yhrb__d2zs1c___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yhrd__d3s66b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yhta1_d2d24b1__1			Proteobacteria	Actinobacteria	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]			beta-N-acetylhexosaminidase activity [GO:0004563]	endo-1,4-beta-xylanase activity [GO:0031176]
d1yhue__d3ubcg___1	Metazoa		Annelida	Verrucomicrobia	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yhuh__d3a9ma___1	Metazoa	Metazoa	Annelida	Arthropoda	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yhuj__d1y0wd___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yhuq__d3wcwe___1	Metazoa	Metazoa	Annelida	Annelida	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yhuq__d4avea___1	Metazoa	Metazoa	Annelida	Nemertea (ribbon worms)	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yhur__d2uulm___1	Metazoa		Annelida		extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1yhur__d3wcwc___1	Metazoa	Metazoa	Annelida	Annelida	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yhux__d1gdia___1	Metazoa	Viridiplantae	Annelida	Streptophyta	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yhwa__d4i6ba___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; axon [GO:0030424]; cell-cell junction [GO:0005911]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; focal adhesion [GO:0005925]; intercalated disc [GO:0014704]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Z disc [GO:0030018]; ATP binding [GO:0005524]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; actin cytoskeleton reorganization [GO:0031532]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; branching morphogenesis of an epithelial tube [GO:0048754]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cerebellum development [GO:0021549]; chromatin remodeling [GO:0006338]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; exocytosis [GO:0006887]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; neuron projection morphogenesis [GO:0048812]; positive regulation of axon extension [GO:0045773]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; response to hypoxia [GO:0001666]; signal transduction by protein phosphorylation [GO:0023014]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; wound healing [GO:0042060]	centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; spindle pole [GO:0000922]; ATP binding [GO:0005524]; ATP-dependent protein binding [GO:0043008]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; G1/S transition of mitotic cell cycle [GO:0000082]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitotic cell cycle [GO:0000278]; mitotic cell cycle checkpoint [GO:0007093]; mitotic spindle organization [GO:0007052]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic process in bone marrow cell [GO:0071866]; negative regulation of cellular senescence [GO:2000773]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of autophagy [GO:0010508]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; protein phosphorylation [GO:0006468]; Rap protein signal transduction [GO:0032486]; Ras protein signal transduction [GO:0007265]; regulation of centriole replication [GO:0046599]; regulation of cytokinesis [GO:0032465]; regulation of synaptic plasticity [GO:0048167]	actin cytoskeleton reorganization [GO:0031532]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; branching morphogenesis of an epithelial tube [GO:0048754]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cerebellum development [GO:0021549]; chromatin remodeling [GO:0006338]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; exocytosis [GO:0006887]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; neuron projection morphogenesis [GO:0048812]; positive regulation of axon extension [GO:0045773]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; response to hypoxia [GO:0001666]; signal transduction by protein phosphorylation [GO:0023014]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; wound healing [GO:0042060]	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; G1/S transition of mitotic cell cycle [GO:0000082]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitotic cell cycle [GO:0000278]; mitotic cell cycle checkpoint [GO:0007093]; mitotic spindle organization [GO:0007052]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic process in bone marrow cell [GO:0071866]; negative regulation of cellular senescence [GO:2000773]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of autophagy [GO:0010508]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; protein phosphorylation [GO:0006468]; Rap protein signal transduction [GO:0032486]; Ras protein signal transduction [GO:0007265]; regulation of centriole replication [GO:0046599]; regulation of cytokinesis [GO:0032465]; regulation of synaptic plasticity [GO:0048167]	actin filament [GO:0005884]; axon [GO:0030424]; cell-cell junction [GO:0005911]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; focal adhesion [GO:0005925]; intercalated disc [GO:0014704]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Z disc [GO:0030018]	centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; spindle pole [GO:0000922]	ATP binding [GO:0005524]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; ATP-dependent protein binding [GO:0043008]; protein-containing complex binding [GO:0044877]; protein serine/threonine kinase activity [GO:0004674]
d1yhya3_d2ihub3__1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]
d1yhya3_d3oe1d3__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1yhza2_d3exfg1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1yhza3_d1t9dc2__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1yi0a2_d1w85d1__1	Viridiplantae		Streptophyta	Firmicutes	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	glycolytic process [GO:0006096]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d1yi0a3_d2c31a3__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	oxalate catabolic process [GO:0033611]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]		acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d1yi2e1_d2hguh2__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1yi5d1_d2ph9c1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d1yi8c__d4r0ng___1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	tryptophanyl-tRNA aminoacylation [GO:0006436]	coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1yi9a1_d3pmsa1__1	Metazoa		Chordata	Bacteroidetes	cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]; central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]	central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]		cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]
d1yifa2_d5aydc___1			Firmicutes	Firmicutes	plasma membrane [GO:0005886]; xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	plasma membrane [GO:0005886]		xylan 1,4-beta-xylosidase activity [GO:0009044]	transferase activity, transferring glycosyl groups [GO:0016757]
d1yifb1_d5jpga___1		Metazoa	Firmicutes	Chordata	plasma membrane [GO:0005886]; xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; lymphatic endothelial cell migration [GO:1904977]	xylan catabolic process [GO:0045493]	lymphatic endothelial cell migration [GO:1904977]	plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	xylan 1,4-beta-xylosidase activity [GO:0009044]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d1yifc1_d1yrza1__1			Firmicutes	Firmicutes	plasma membrane [GO:0005886]; xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	xylan 1,4-beta-xylosidase activity [GO:0009044]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]		xylan 1,4-beta-xylosidase activity [GO:0009044]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d1yifc2_d1utwc1__1			Firmicutes		plasma membrane [GO:0005886]; xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]		plasma membrane [GO:0005886]		xylan 1,4-beta-xylosidase activity [GO:0009044]	
d1yifd1_d1y7bd1__1			Firmicutes	Firmicutes	plasma membrane [GO:0005886]; xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]		xylan 1,4-beta-xylosidase activity [GO:0009044]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1yifd1_d5gzga___1		Metazoa	Firmicutes	Chordata	plasma membrane [GO:0005886]; xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	xylan catabolic process [GO:0045493]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	xylan 1,4-beta-xylosidase activity [GO:0009044]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d1yifd2_d2exkb2__1			Firmicutes	Firmicutes	plasma membrane [GO:0005886]; xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]		xylan 1,4-beta-xylosidase activity [GO:0009044]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d1yihb1_d1ecoa___1	Metazoa	Metazoa	Chordata	Arthropoda	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yihb1_d2uumo___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1yirb2_d1qpqe2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cytosol [GO:0005829]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1yitb1_d4rd3a2__1			Euryarchaeota	Crenarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	translation [GO:0006412]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	ribosome [GO:0005840]	cytosol [GO:0005829]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1yitf1_d1m1kh___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d1yj4b__d5diqf___1	Fungi	Metazoa	Ascomycota	Chordata	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	sesquiterpenoid biosynthetic process [GO:0016106]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d1yj6b2_d4zbdb1__1	Metazoa	Fungi	Chordata	Basidiomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	
d1yj6c1_d3gx0a2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	disulfide oxidoreductase activity [GO:0015036]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	disulfide oxidoreductase activity [GO:0015036]; peroxidase activity [GO:0004601]
d1yj9a1_d2zjqa1__1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	cytosolic large ribosomal subunit [GO:0022625]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d1yjdh1_d1mcqb2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; SH3/SH2 adaptor activity [GO:0005070]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cytokine biosynthetic process [GO:0042089]; humoral immune response [GO:0006959]; immune system process [GO:0002376]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of viral genome replication [GO:0045070]; regulation of defense response to virus by virus [GO:0050690]; regulation of regulatory T cell differentiation [GO:0045589]; regulatory T cell differentiation [GO:0045066]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cytokine biosynthetic process [GO:0042089]; humoral immune response [GO:0006959]; immune system process [GO:0002376]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of viral genome replication [GO:0045070]; regulation of defense response to virus by virus [GO:0050690]; regulation of regulatory T cell differentiation [GO:0045589]; regulatory T cell differentiation [GO:0045066]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]		coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; SH3/SH2 adaptor activity [GO:0005070]	
d1yjdl2_d1a1ob___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; SH3/SH2 adaptor activity [GO:0005070]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cytokine biosynthetic process [GO:0042089]; humoral immune response [GO:0006959]; immune system process [GO:0002376]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of viral genome replication [GO:0045070]; regulation of defense response to virus by virus [GO:0050690]; regulation of regulatory T cell differentiation [GO:0045589]; regulatory T cell differentiation [GO:0045066]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cytokine biosynthetic process [GO:0042089]; humoral immune response [GO:0006959]; immune system process [GO:0002376]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of viral genome replication [GO:0045070]; regulation of defense response to virus by virus [GO:0050690]; regulation of regulatory T cell differentiation [GO:0045589]; regulatory T cell differentiation [GO:0045066]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; SH3/SH2 adaptor activity [GO:0005070]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1yjgb__d1ggqa___1			Spirochaetes	Spirochaetes	cell outer membrane [GO:0009279]	external side of cell outer membrane [GO:0031240]; membrane [GO:0016020]			cell outer membrane [GO:0009279]	external side of cell outer membrane [GO:0031240]; membrane [GO:0016020]		
d1yjgb__d2ga0d___1			Spirochaetes	Spirochaetes	cell outer membrane [GO:0009279]	cell outer membrane [GO:0009279]			cell outer membrane [GO:0009279]	cell outer membrane [GO:0009279]		
d1yjha__d2ddsa___1	Metazoa		Arthropoda	Firmicutes	extracellular space [GO:0005615]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide transport [GO:0030185]; phosphatidylinositol dephosphorylation [GO:0046856]; vasodilation in other organism [GO:0044552]	extracellular region [GO:0005576]; sphingomyelin phosphodiesterase activity [GO:0004767]; hemolysis in other organism [GO:0044179]	nitric oxide transport [GO:0030185]; phosphatidylinositol dephosphorylation [GO:0046856]; vasodilation in other organism [GO:0044552]	hemolysis in other organism [GO:0044179]	extracellular space [GO:0005615]	extracellular region [GO:0005576]	heme binding [GO:0020037]; iron ion binding [GO:0005506]	sphingomyelin phosphodiesterase activity [GO:0004767]
d1yjia__d1ffud2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1yjja__d1n5xb2__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1yjma1_d5jejb___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; double-stranded DNA binding [GO:0003690]; nucleoside monophosphate kinase activity [GO:0050145]; polynucleotide 3'-phosphatase activity [GO:0046403]; dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide phosphorylation [GO:0046939]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide phosphorylation [GO:0046939]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; double-stranded DNA binding [GO:0003690]; nucleoside monophosphate kinase activity [GO:0050145]; polynucleotide 3'-phosphatase activity [GO:0046403]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]
d1yjta1_d2kt3a___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]; antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cell [GO:0005623]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; mercury (II) reductase activity [GO:0016152]; mercury ion binding [GO:0045340]; NADP binding [GO:0050661]; oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor [GO:0016668]; cell redox homeostasis [GO:0045454]; detoxification of mercury ion [GO:0050787]; metal ion transport [GO:0030001]	antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cell redox homeostasis [GO:0045454]; detoxification of mercury ion [GO:0050787]; metal ion transport [GO:0030001]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	cell [GO:0005623]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; mercury (II) reductase activity [GO:0016152]; mercury ion binding [GO:0045340]; NADP binding [GO:0050661]; oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor [GO:0016668]
d1yjwi1_d2qbii1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d1yjxa__d5um0d1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]		bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]
d1yjxc__d4eo9a___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]		bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]
d1yjxe__d3ntla1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]		bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]	
d1yjxf__d1c7za___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; animal organ regeneration [GO:0031100]; carbohydrate phosphorylation [GO:0046835]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; positive regulation of glucokinase activity [GO:0033133]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	animal organ regeneration [GO:0031100]; carbohydrate phosphorylation [GO:0046835]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; positive regulation of glucokinase activity [GO:0033133]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]	6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]
d1yjxf__d1riia___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; identical protein binding [GO:0042802]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; identical protein binding [GO:0042802]
d1yjxh__d1c81a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; animal organ regeneration [GO:0031100]; carbohydrate phosphorylation [GO:0046835]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; positive regulation of glucokinase activity [GO:0033133]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	animal organ regeneration [GO:0031100]; carbohydrate phosphorylation [GO:0046835]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; positive regulation of glucokinase activity [GO:0033133]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]	6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]
d1yjxk__d2p77a___1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	catalytic activity [GO:0003824]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]		bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]	catalytic activity [GO:0003824]
d1yjxl__d3bifa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	cytosol [GO:0005829]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]	6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]
d1yk3c__d4evya1__1			Actinobacteria	Proteobacteria	acyl-CoA hydrolase activity [GO:0047617]; N-acyltransferase activity [GO:0016410]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; siderophore biosynthetic process from catechol [GO:0019540]	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]; response to antibiotic [GO:0046677]	siderophore biosynthetic process from catechol [GO:0019540]	response to antibiotic [GO:0046677]			acyl-CoA hydrolase activity [GO:0047617]; N-acyltransferase activity [GO:0016410]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]
d1yk3f__d5f49c___1			Actinobacteria		acyl-CoA hydrolase activity [GO:0047617]; N-acyltransferase activity [GO:0016410]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; siderophore biosynthetic process from catechol [GO:0019540]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]	siderophore biosynthetic process from catechol [GO:0019540]				acyl-CoA hydrolase activity [GO:0047617]; N-acyltransferase activity [GO:0016410]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]
d1yk3g__d1kuxa___1		Metazoa	Actinobacteria	Chordata	acyl-CoA hydrolase activity [GO:0047617]; N-acyltransferase activity [GO:0016410]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; siderophore biosynthetic process from catechol [GO:0019540]	perinuclear region of cytoplasm [GO:0048471]; aralkylamine N-acetyltransferase activity [GO:0004059]; cellular response to cAMP [GO:0071320]; circadian rhythm [GO:0007623]; melatonin biosynthetic process [GO:0030187]; N-terminal protein amino acid acetylation [GO:0006474]	siderophore biosynthetic process from catechol [GO:0019540]	cellular response to cAMP [GO:0071320]; circadian rhythm [GO:0007623]; melatonin biosynthetic process [GO:0030187]; N-terminal protein amino acid acetylation [GO:0006474]		perinuclear region of cytoplasm [GO:0048471]	acyl-CoA hydrolase activity [GO:0047617]; N-acyltransferase activity [GO:0016410]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	aralkylamine N-acetyltransferase activity [GO:0004059]
d1yk9a__d1cs4a___1		Metazoa	Actinobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; guanylate cyclase activity [GO:0004383]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; peptide receptor activity [GO:0001653]; cAMP biosynthetic process [GO:0006171]; cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165]	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	cAMP biosynthetic process [GO:0006171]; cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; guanylate cyclase activity [GO:0004383]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; peptide receptor activity [GO:0001653]	adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d1ykbd__d1v7nz___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]; acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]
d1ykbf__d1itla___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]; acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]; activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]
d1ykcb2_d2pn8d1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d1ykfb2_d1gz3b1__1		Metazoa	Firmicutes	Chordata	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]; malate metabolic process [GO:0006108]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031]; tricarboxylic acid cycle [GO:0006099]		malate metabolic process [GO:0006108]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031]; tricarboxylic acid cycle [GO:0006099]		intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]
d1ykfc2_d1ntoh2__1			Firmicutes	Crenarchaeota	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]					isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]
d1ykfc2_d1orra1__1			Firmicutes	Proteobacteria	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	CDP-abequose epimerase activity [GO:0047732]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]			isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	CDP-abequose epimerase activity [GO:0047732]
d1ykpg__d3hhxa___1			Proteobacteria	Actinobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]; aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]
d1ykxx__d1slya2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; peptidoglycan-based cell wall [GO:0009274]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; lyase activity [GO:0016829]; lytic endotransglycosylase activity [GO:0008932]; lytic transglycosylase activity [GO:0008933]; cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; peptidoglycan-based cell wall [GO:0009274]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; lyase activity [GO:0016829]; lytic endotransglycosylase activity [GO:0008932]; lytic transglycosylase activity [GO:0008933]
d1ykyx__d4i7oa1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1yl311_d1vs8q1__1												
d1yl381_d3df431__1												
d1yl3j2_d3o2oh___1				Proteobacteria		chaperone binding [GO:0051087]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]		protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]				chaperone binding [GO:0051087]
d1yl3n1_d2i2tk1__1												
d1yl4h2_d2qale2__1												
d1yl4r1_d2vhoo1__1												
d1ylab2_d2pe6a2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; filopodium tip [GO:0032433]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-ubiquitin ligase activity [GO:0034450]; cellular response to interferon-beta [GO:0035458]; free ubiquitin chain polymerization [GO:0010994]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]; ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cellular response to interferon-beta [GO:0035458]; free ubiquitin chain polymerization [GO:0010994]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]; filopodium tip [GO:0032433]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-ubiquitin ligase activity [GO:0034450]	ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]
d1ylbb__d2vw7b2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	chloroplast thylakoid membrane [GO:0009535]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1ylha1_d4rcga1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cell [GO:0005623]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; cellular response to glucose stimulus [GO:0071333]; cellular response to iron ion starvation [GO:0010106]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to host immune response [GO:0052572]; response to lipid [GO:0033993]; response to starvation [GO:0042594]	gluconeogenesis [GO:0006094]	cellular response to glucose stimulus [GO:0071333]; cellular response to iron ion starvation [GO:0010106]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to host immune response [GO:0052572]; response to lipid [GO:0033993]; response to starvation [GO:0042594]	cytoplasm [GO:0005737]	cell [GO:0005623]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]	GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]
d1ylia__d1s5uc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acyl-CoA hydrolase activity [GO:0047617]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]; acyl-CoA metabolic process [GO:0006637]	plasma membrane [GO:0005886]; acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]; lipid metabolic process [GO:0006629]	acyl-CoA metabolic process [GO:0006637]	lipid metabolic process [GO:0006629]	cytosol [GO:0005829]	plasma membrane [GO:0005886]	acyl-CoA hydrolase activity [GO:0047617]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]	acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]
d1ylkc1_d1i6pa___1			Actinobacteria	Proteobacteria	plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]		carbon utilization [GO:0015976]	plasma membrane [GO:0005886]	cytosol [GO:0005829]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1ylqb2_d1huzb4__1		Metazoa	Euryarchaeota	Chordata	nucleotidyltransferase activity [GO:0016779]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	nucleotidyltransferase activity [GO:0016779]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d1ylva__d3tnoa___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d1ym7d1_d2dlra1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]; alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]; cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein phosphorylation [GO:0006468]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	axon terminus [GO:0043679]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to amphetamine [GO:0001975]	cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein phosphorylation [GO:0006468]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to amphetamine [GO:0001975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]	axon terminus [GO:0043679]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]	G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]
d1ymba__d2hbdb___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ymca__d2uulj___1	Metazoa		Chordata		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1ymha1_d3jwdd2__1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell wall [GO:0005618]; extracellular region [GO:0005576]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1ymhb1_d4y8dd1__1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; presynapse [GO:0098793]; vesicle [GO:0031982]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; clathrin binding [GO:0030276]; cyclin binding [GO:0030332]; protein serine/threonine kinase activity [GO:0004674]; cell cycle [GO:0007049]; chaperone cofactor-dependent protein refolding [GO:0051085]; clathrin coat disassembly [GO:0072318]; clathrin-coated pit assembly [GO:1905224]; clathrin-dependent endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; Golgi organization [GO:0007030]; Golgi to lysosome transport [GO:0090160]; membrane organization [GO:0061024]; negative regulation of neuron projection development [GO:0010977]; protein localization to Golgi apparatus [GO:0034067]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle uncoating [GO:0016191]	pathogenesis [GO:0009405]	cell cycle [GO:0007049]; chaperone cofactor-dependent protein refolding [GO:0051085]; clathrin coat disassembly [GO:0072318]; clathrin-coated pit assembly [GO:1905224]; clathrin-dependent endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; Golgi organization [GO:0007030]; Golgi to lysosome transport [GO:0090160]; membrane organization [GO:0061024]; negative regulation of neuron projection development [GO:0010977]; protein localization to Golgi apparatus [GO:0034067]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle uncoating [GO:0016191]	cell wall [GO:0005618]; extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; presynapse [GO:0098793]; vesicle [GO:0031982]	IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; clathrin binding [GO:0030276]; cyclin binding [GO:0030332]; protein serine/threonine kinase activity [GO:0004674]
d1ymhb1_d5te7l2__1			Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	pathogenesis [GO:0009405]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell wall [GO:0005618]; extracellular region [GO:0005576]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]	structural molecule activity [GO:0005198]
d1ymhb2_d3t2nm2__1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]; basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	pathogenesis [GO:0009405]	basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	cell wall [GO:0005618]; extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]	calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]
d1ymhd2_d4at6b1__1			Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]		IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]	
d1ymma1_d5x5wb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell-cell adherens junction [GO:0005913]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of viral entry into host cell [GO:0046598]; regulation of synapse assembly [GO:0051963]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of viral entry into host cell [GO:0046598]; regulation of synapse assembly [GO:0051963]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell-cell adherens junction [GO:0005913]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; synapse [GO:0045202]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cell adhesion molecule binding [GO:0050839]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]
d1ymmb2_d3c5jb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d1ymmd1_d4gw4l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ymme1_d6ehvx1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1ympa__d5d66a2__1	Metazoa		Chordata	Proteobacteria	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transmembrane signaling receptor activity [GO:0004888]; animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell differentiation in spinal cord [GO:0021515]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; endocardial cell differentiation [GO:0060956]; endocardial cushion development [GO:0003197]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epidermis development [GO:0008544]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glial cell differentiation [GO:0010001]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell death [GO:0060548]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neural tube development [GO:0021915]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; osteoblast fate commitment [GO:0002051]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral transcription [GO:0050434]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of cardioblast proliferation [GO:0003264]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of gene expression [GO:0010468]; regulation of inner ear auditory receptor cell differentiation [GO:0045607]; regulation of neurogenesis [GO:0050767]; regulation of Notch signaling pathway [GO:0008593]; regulation of somitogenesis [GO:0014807]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous blood vessel morphogenesis [GO:0048845]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	integral component of membrane [GO:0016021]	animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell differentiation in spinal cord [GO:0021515]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; endocardial cell differentiation [GO:0060956]; endocardial cushion development [GO:0003197]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epidermis development [GO:0008544]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glial cell differentiation [GO:0010001]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; in utero embryonic development [GO:0001701]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell death [GO:0060548]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; osteoblast fate commitment [GO:0002051]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral transcription [GO:0050434]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of cardioblast proliferation [GO:0003264]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of gene expression [GO:0010468]; regulation of inner ear auditory receptor cell differentiation [GO:0045607]; regulation of neurogenesis [GO:0050767]; regulation of Notch signaling pathway [GO:0008593]; regulation of somitogenesis [GO:0014807]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous blood vessel morphogenesis [GO:0048845]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle [GO:0001726]	integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transmembrane signaling receptor activity [GO:0004888]	
d1ympb__d5eida___1	Metazoa	Viridiplantae	Chordata	Streptophyta	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transmembrane signaling receptor activity [GO:0004888]; animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell differentiation in spinal cord [GO:0021515]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; endocardial cell differentiation [GO:0060956]; endocardial cushion development [GO:0003197]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epidermis development [GO:0008544]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glial cell differentiation [GO:0010001]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell death [GO:0060548]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neural tube development [GO:0021915]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; osteoblast fate commitment [GO:0002051]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral transcription [GO:0050434]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of cardioblast proliferation [GO:0003264]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of gene expression [GO:0010468]; regulation of inner ear auditory receptor cell differentiation [GO:0045607]; regulation of neurogenesis [GO:0050767]; regulation of Notch signaling pathway [GO:0008593]; regulation of somitogenesis [GO:0014807]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous blood vessel morphogenesis [GO:0048845]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	chloroplast outer membrane [GO:0009707]; cytoplasm [GO:0005737]; integral component of chloroplast outer membrane [GO:0031359]; nucleus [GO:0005634]; chloroplast targeting sequence binding [GO:0030941]; glycolipid binding [GO:0051861]; protein targeting to chloroplast [GO:0045036]	animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell differentiation in spinal cord [GO:0021515]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; endocardial cell differentiation [GO:0060956]; endocardial cushion development [GO:0003197]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epidermis development [GO:0008544]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glial cell differentiation [GO:0010001]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; in utero embryonic development [GO:0001701]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell death [GO:0060548]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; osteoblast fate commitment [GO:0002051]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral transcription [GO:0050434]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of cardioblast proliferation [GO:0003264]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of gene expression [GO:0010468]; regulation of inner ear auditory receptor cell differentiation [GO:0045607]; regulation of neurogenesis [GO:0050767]; regulation of Notch signaling pathway [GO:0008593]; regulation of somitogenesis [GO:0014807]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous blood vessel morphogenesis [GO:0048845]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	protein targeting to chloroplast [GO:0045036]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle [GO:0001726]	chloroplast outer membrane [GO:0009707]; cytoplasm [GO:0005737]; integral component of chloroplast outer membrane [GO:0031359]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transmembrane signaling receptor activity [GO:0004888]	chloroplast targeting sequence binding [GO:0030941]; glycolipid binding [GO:0051861]
d1ymub__d5wq0c___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	
d1ymva__d2zayb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	
d1ymwa__d2zpoa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]
d1yn7b2_d2yc1d___1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	defense response [GO:0006952]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]
d1ynba1_d2gz4a1__1			Euryarchaeota	Proteobacteria	5'-deoxynucleotidase activity [GO:0002953]						5'-deoxynucleotidase activity [GO:0002953]	
d1ynhd__d4e4jb___1			Proteobacteria	Tenericutes	N-succinylarginine dihydrolase activity [GO:0009015]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]	cytoplasm [GO:0005737]; arginine deiminase activity [GO:0016990]; arginine catabolic process to ornithine [GO:0019547]	arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]	arginine catabolic process to ornithine [GO:0019547]		cytoplasm [GO:0005737]	N-succinylarginine dihydrolase activity [GO:0009015]	arginine deiminase activity [GO:0016990]
d1ynkl2_d2fx8n1__1	Metazoa		Chordata			host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d1ynll1_d1z3gm2__1	Metazoa		Chordata	Apicomplexa		cell surface [GO:0009986]; integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]				cell surface [GO:0009986]; integral component of membrane [GO:0016021]		calcium ion binding [GO:0005509]
d1ynoa1_d5tmaa2__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1ynoa2_d1yi1a2__1		Viridiplantae	Proteobacteria	Streptophyta	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	mandelate catabolic process [GO:0019596]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1ynoa3_d5deib1__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	mandelate catabolic process [GO:0019596]	mandelate catabolic process [GO:0019596]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1ynra__d1dw3b___1			Aquificae	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1ynrd__d1m70d2__1			Aquificae	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1ynta2_d1mclb2__1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]		IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]	
d1yntb1_d5f93d1__1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]		IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]	
d1yntf1_d1kzqa2__1			Firmicutes	Apicomplexa	cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]	membrane [GO:0016020]; symbiont-containing vacuole [GO:0020003]	pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]	membrane [GO:0016020]; symbiont-containing vacuole [GO:0020003]	IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]	
d1yo1a__d1avna___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1yo2a__d2aw1a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1yoaa1_d2e83a___1			Deinococcus-Thermus	Proteobacteria	FMN binding [GO:0010181]	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	FMN binding [GO:0010181]	cofactor binding [GO:0048037]
d1yoba1_d3b6ia___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; nitrogen fixation [GO:0009399]	cytosol [GO:0005829]; membrane [GO:0016020]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]	nitrogen fixation [GO:0009399]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; membrane [GO:0016020]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1yobb__d1qrda___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	nitrogen fixation [GO:0009399]	aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]
d1yp1a__d4q1la___1		Metazoa		Chordata		extracellular region [GO:0005576]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; fibrinolysis [GO:0042730]		fibrinolysis [GO:0042730]		extracellular region [GO:0005576]		metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1yp2a1_d3gosb1__1	Viridiplantae		Streptophyta	Proteobacteria	amyloplast [GO:0009501]; chloroplast [GO:0009507]; ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]; glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cytoplasm [GO:0005737]; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	amyloplast [GO:0009501]; chloroplast [GO:0009507]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]
d1yp2d1_d3dhob___1	Viridiplantae		Streptophyta	Firmicutes	amyloplast [GO:0009501]; chloroplast [GO:0009507]; ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]; glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	response to antibiotic [GO:0046677]	amyloplast [GO:0009501]; chloroplast [GO:0009507]		ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]	transferase activity, transferring acyl groups [GO:0016746]
d1yp3c1_d1qrea___1	Viridiplantae		Streptophyta	Euryarchaeota	amyloplast [GO:0009501]; chloroplast [GO:0009507]; ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]; glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]		amyloplast [GO:0009501]; chloroplast [GO:0009507]		ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]
d1yp4a1_d2qkxa2__1	Viridiplantae		Streptophyta	Actinobacteria	amyloplast [GO:0009501]; chloroplast [GO:0009507]; ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]; glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]; adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	amyloplast [GO:0009501]; chloroplast [GO:0009507]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]
d1yp4b1_d5jxxe___1	Viridiplantae		Streptophyta	Proteobacteria	amyloplast [GO:0009501]; chloroplast [GO:0009507]; ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]; glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	lipid A biosynthetic process [GO:0009245]	amyloplast [GO:0009501]; chloroplast [GO:0009507]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]
d1yp4c1_d1hm8b1__1	Viridiplantae		Streptophyta	Firmicutes	amyloplast [GO:0009501]; chloroplast [GO:0009507]; ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]; glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	amyloplast [GO:0009501]; chloroplast [GO:0009507]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d1yp6a1_d5xnaa1__1	Metazoa	Metazoa	Chordata	Tardigrada (water bears)	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone activity [GO:0005186]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to food [GO:0071240]; cellular response to lipid [GO:0071396]; cellular response to starvation [GO:0009267]; cellular response to testosterone stimulus [GO:0071394]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]; response to stilbenoid [GO:0035634]	extracellular region [GO:0005576]; lipid binding [GO:0008289]	aerobic respiration [GO:0009060]; cellular response to food [GO:0071240]; cellular response to lipid [GO:0071396]; cellular response to starvation [GO:0009267]; cellular response to testosterone stimulus [GO:0071394]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]; response to stilbenoid [GO:0035634]		cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	insulin-activated receptor activity [GO:0005009]; pheromone activity [GO:0005186]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	lipid binding [GO:0008289]
d1ypci__d1tm1i___1	Viridiplantae		Streptophyta	Firmicutes	serine-type endopeptidase inhibitor activity [GO:0004867]; response to wounding [GO:0009611]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	response to wounding [GO:0009611]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]	serine-type endopeptidase inhibitor activity [GO:0004867]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1ypda3_d4k9ma3__1				Proteobacteria		benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1ypdb3_d1v5ea3__1				Firmicutes		magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]						magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d1ypib__d1mssb___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d1ypof__d3g8ka___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]	blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]		extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	carbohydrate binding [GO:0030246]
d1yppa__d1mjza___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; membrane [GO:0016020]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; membrane [GO:0016020]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]
d1yppb__d3ld3b___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d1ypub__d1hyra___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; MHC class I protein binding [GO:0042288]; MHC class Ib receptor activity [GO:0032394]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]	blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	carbohydrate binding [GO:0030246]; MHC class Ib receptor activity [GO:0032394]; MHC class I protein binding [GO:0042288]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]
d1ypub__d4c9fb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; (1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	(1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]
d1ypza2_d1kg0b2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1ypzc1_d2bmka1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ypze1_d5m30f1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ypze2_d1tzgi2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ypzf1_d4ocmf___1	Metazoa	Fungi	Chordata	Ascomycota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	proteasome complex [GO:0000502]; proteasome regulatory particle, lid subcomplex [GO:0008541]; proteasome storage granule [GO:0034515]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; ubiquitin-dependent protein catabolic process [GO:0006511]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	proteasome complex [GO:0000502]; proteasome regulatory particle, lid subcomplex [GO:0008541]; proteasome storage granule [GO:0034515]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ypzf1_d5dk3f1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ypzf2_d1t1zb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1ypzf2_d1ub5l1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ypzg1_d5n88a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; nuclear heterochromatin [GO:0005720]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; RNA binding [GO:0003723]; supercoiled DNA binding [GO:0097100]; transcription coactivator activity [GO:0003713]; establishment of integrated proviral latency [GO:0075713]; mRNA 5'-splice site recognition [GO:0000395]; nuclear transport [GO:0051169]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	establishment of integrated proviral latency [GO:0075713]; mRNA 5'-splice site recognition [GO:0000395]; nuclear transport [GO:0051169]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; nuclear heterochromatin [GO:0005720]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; RNA binding [GO:0003723]; supercoiled DNA binding [GO:0097100]; transcription coactivator activity [GO:0003713]
d1ypzg2_d1il1a1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ypzh1_d5ifhl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1ypzh2_d3p4nb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1ypzh2_d5e5mb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1yq2a1_d1jz1j1__1			Actinobacteria		beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		beta-galactosidase complex [GO:0009341]		beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	
d1yq2a2_d3t0ba4__1			Actinobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1yq2a4_d1snzb___1		Metazoa	Actinobacteria	Chordata	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	carbohydrate metabolic process [GO:0005975]	galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	beta-galactosidase complex [GO:0009341]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d1yq2a5_d3gxna1__1		Metazoa	Actinobacteria	Chordata	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	beta-galactosidase complex [GO:0009341]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d1yq2b2_d2vr4b3__1			Actinobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	beta-mannosidase activity [GO:0004567]
d1yq2b4_d3sepa5__1			Actinobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1yq2c1_d3i3da4__1			Actinobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1yq2c1_d3t2qa2__1			Actinobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1yq2c2_d3i3dd4__1			Actinobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1yq2c3_d3t2pc1__1			Actinobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1yq2c5_d1jyzm5__1			Actinobacteria		beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		beta-galactosidase complex [GO:0009341]		beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	
d1yq2d1_d1bgmp1__1			Actinobacteria		beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		beta-galactosidase complex [GO:0009341]		beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	
d1yq2d2_d4jkmb2__1			Actinobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	carbohydrate metabolic process [GO:0005975]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	beta-galactosidase complex [GO:0009341]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d1yq2d5_d1xskb4__1			Actinobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d1yq2e1_d1jyvb1__1			Actinobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1yq2e2_d3t08c2__1			Actinobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1yq2f1_d5czkb2__1			Actinobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	beta-galactosidase complex [GO:0009341]	cytosol [GO:0005829]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d1yq2f2_d4duvc4__1			Actinobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d1yq2f3_d1bgml3__1			Actinobacteria		beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		beta-galactosidase complex [GO:0009341]		beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	
d1yq2f3_d1w90a1__1		Fungi	Actinobacteria	Chytridiomycota	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		beta-galactosidase complex [GO:0009341]		beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	
d1yq2f4_d2f1aa2__1		Metazoa	Actinobacteria	Arthropoda	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d1yq3b1_d3ab5a___1	Metazoa		Chordata	Rhodophyta	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	chloroplast [GO:0009507]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]		mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	chloroplast [GO:0009507]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1yq4b1_d1qlab3__1	Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]		aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]		mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]		2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	
d1yqka1_d1muna___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]
d1yqma1_d1kg7a___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]
d1yqna1_d3q8hc___1			Proteobacteria	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d1yqqc__d1ou4c___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; guanosine phosphorylase activity [GO:0047975]; identical protein binding [GO:0042802]; inosine nucleosidase activity [GO:0047724]; purine-nucleoside phosphorylase activity [GO:0004731]; deoxyguanosine catabolic process [GO:0006161]; deoxyinosine catabolic process [GO:0006149]; guanosine catabolic process [GO:0046115]; inosine catabolic process [GO:0006148]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleobase-containing small molecule metabolic process [GO:0055086]; protein hexamerization [GO:0034214]; purine nucleoside catabolic process [GO:0006152]; xanthosine catabolic process [GO:1903228]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	deoxyguanosine catabolic process [GO:0006161]; deoxyinosine catabolic process [GO:0006149]; guanosine catabolic process [GO:0046115]; inosine catabolic process [GO:0006148]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleobase-containing small molecule metabolic process [GO:0055086]; protein hexamerization [GO:0034214]; purine nucleoside catabolic process [GO:0006152]; xanthosine catabolic process [GO:1903228]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	guanosine phosphorylase activity [GO:0047975]; identical protein binding [GO:0042802]; inosine nucleosidase activity [GO:0047724]; purine-nucleoside phosphorylase activity [GO:0004731]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]
d1yqra1_d4e9ea___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	chromatin [GO:0000785]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; endodeoxyribonuclease activity [GO:0004520]; pyrimidine-specific mismatch base pair DNA N-glycosylase activity [GO:0008263]; satellite DNA binding [GO:0003696]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; response to estradiol [GO:0032355]; response to radiation [GO:0009314]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	depyrimidination [GO:0045008]; DNA repair [GO:0006281]; response to estradiol [GO:0032355]; response to radiation [GO:0009314]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	chromatin [GO:0000785]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; endodeoxyribonuclease activity [GO:0004520]; pyrimidine-specific mismatch base pair DNA N-glycosylase activity [GO:0008263]; satellite DNA binding [GO:0003696]
d1yqvl1_d3rugd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1yqvl2_d4whtj1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	viral envelope [GO:0019031]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	viral envelope [GO:0019031]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1yqya1_d1jana___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1yqya2_d4xsgb___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	extracellular region [GO:0005576]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d1yr5a__d2lp3b___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]
d1yr8a2_d1ng1a2__1			Euryarchaeota	Deinococcus-Thermus	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]		SRP-dependent cotranslational protein targeting to membrane [GO:0006614]		signal recognition particle [GO:0048500]	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1yr8a2_d4dhea1__1			Euryarchaeota	Proteobacteria	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; division septum assembly [GO:0000917]		division septum assembly [GO:0000917]			GTP binding [GO:0005525]; hydrolase activity [GO:0016787]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]
d1yrbb2_d4q01b___1		Metazoa	Euryarchaeota	Chordata	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]; actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]		actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]	GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]
d1yrca__d2d09a1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	(+)-camphor catabolic process [GO:0019383]	oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1yrec__d2j8ra___1			Proteobacteria	Proteobacteria	N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]					N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1yrgb__d1fqvi2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; GTPase activator activity [GO:0005096]; positive regulation of protein export from nucleus [GO:0046827]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	positive regulation of protein export from nucleus [GO:0046827]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	GTPase activator activity [GO:0005096]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]
d1yrka1_d1tjma1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium-independent protein kinase C activity [GO:0004699]; enzyme activator activity [GO:0008047]; enzyme binding [GO:0019899]; insulin receptor substrate binding [GO:0043560]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; cell chemotaxis [GO:0060326]; cell cycle [GO:0007049]; cellular response to angiotensin [GO:1904385]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hydroperoxide [GO:0071447]; cellular senescence [GO:0090398]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; histone phosphorylation [GO:0016572]; immunoglobulin mediated immune response [GO:0016064]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-10 production [GO:0032613]; interleukin-12 production [GO:0032615]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inflammatory response [GO:0050728]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein binding [GO:0032091]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of glucosylceramide catabolic process [GO:2000753]; positive regulation of phospholipid scramblase activity [GO:1900163]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of sphingomyelin catabolic process [GO:2000755]; positive regulation of superoxide anion generation [GO:0032930]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of mRNA stability [GO:0043488]; regulation of signaling receptor activity [GO:0010469]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; termination of signal transduction [GO:0023021]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; B cell proliferation [GO:0042100]; cell chemotaxis [GO:0060326]; cell cycle [GO:0007049]; cellular response to angiotensin [GO:1904385]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hydroperoxide [GO:0071447]; cellular senescence [GO:0090398]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; histone phosphorylation [GO:0016572]; immunoglobulin mediated immune response [GO:0016064]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-10 production [GO:0032613]; interleukin-12 production [GO:0032615]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of inflammatory response [GO:0050728]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein binding [GO:0032091]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of glucosylceramide catabolic process [GO:2000753]; positive regulation of phospholipid scramblase activity [GO:1900163]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of sphingomyelin catabolic process [GO:2000755]; positive regulation of superoxide anion generation [GO:0032930]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of mRNA stability [GO:0043488]; regulation of signaling receptor activity [GO:0010469]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; termination of signal transduction [GO:0023021]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	azurophil granule lumen [GO:0035578]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; calcium-independent protein kinase C activity [GO:0004699]; enzyme activator activity [GO:0008047]; enzyme binding [GO:0019899]; insulin receptor substrate binding [GO:0043560]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]
d1yroa__d1cnsb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]		alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	chitinase activity [GO:0004568]
d1yrob1_d1pzyd___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d1yrob1_d5vqmb___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]		alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	
d1yrva1_d2pwqa1__1	Metazoa		Chordata	Apicomplexa	HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]	ATP binding [GO:0005524]; transferase activity [GO:0016740]	DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]		HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]		ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]	ATP binding [GO:0005524]; transferase activity [GO:0016740]
d1yrye__d1xe3c1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	purine nucleoside metabolic process [GO:0042278]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]		drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d1yrza1_d2ovua___1		Viridiplantae	Firmicutes	Streptophyta	xylan 1,4-beta-xylosidase activity [GO:0009044]; carbohydrate metabolic process [GO:0005975]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]	carbohydrate metabolic process [GO:0005975]	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]			xylan 1,4-beta-xylosidase activity [GO:0009044]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]
d1yrzb2_d5ayde___1			Firmicutes	Firmicutes	xylan 1,4-beta-xylosidase activity [GO:0009044]; carbohydrate metabolic process [GO:0005975]	transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]			xylan 1,4-beta-xylosidase activity [GO:0009044]	transferase activity, transferring glycosyl groups [GO:0016757]
d1ys2x__d3ia2b___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]		metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]
d1ys6b1_d1gxpb___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; calcium ion binding [GO:0005509]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; magnesium ion binding [GO:0000287]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; growth involved in symbiotic interaction [GO:0044110]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	growth involved in symbiotic interaction [GO:0044110]	phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	calcium ion binding [GO:0005509]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; magnesium ion binding [GO:0000287]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1ys7a2_d2nt3a___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; calcium ion binding [GO:0005509]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; magnesium ion binding [GO:0000287]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; growth involved in symbiotic interaction [GO:0044110]	phosphorelay signal transduction system [GO:0000160]	growth involved in symbiotic interaction [GO:0044110]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]		calcium ion binding [GO:0005509]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; magnesium ion binding [GO:0000287]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	
d1ysba1_d3oj6a___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d1ysbb2_d1rb7b___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]
d1ysdb2_d1ctta1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; pyrimidine nucleoside binding [GO:0001884]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; nucleobase-containing small molecule interconversion [GO:0015949]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytidine deamination [GO:0009972]; deoxycytidine catabolic process [GO:0006217]; nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; pyrimidine nucleoside binding [GO:0001884]; zinc ion binding [GO:0008270]
d1yslb1_d1u6eb2__1			Firmicutes	Actinobacteria	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		cytoplasm [GO:0005737]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d1ysxa1_d5otbc3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d1yt3a2_d1yt3a1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3'-5'-exoribonuclease activity [GO:0000175]; nucleic acid binding [GO:0003676]; nucleotide binding [GO:0000166]; ribonuclease D activity [GO:0033890]; tRNA 3'-end processing [GO:0042780]	cytoplasm [GO:0005737]; 3'-5'-exoribonuclease activity [GO:0000175]; nucleic acid binding [GO:0003676]; nucleotide binding [GO:0000166]; ribonuclease D activity [GO:0033890]; tRNA 3'-end processing [GO:0042780]	tRNA 3'-end processing [GO:0042780]	tRNA 3'-end processing [GO:0042780]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3'-5'-exoribonuclease activity [GO:0000175]; nucleic acid binding [GO:0003676]; nucleotide binding [GO:0000166]; ribonuclease D activity [GO:0033890]	3'-5'-exoribonuclease activity [GO:0000175]; nucleic acid binding [GO:0003676]; nucleotide binding [GO:0000166]; ribonuclease D activity [GO:0033890]
d1yt3a3_d2kfza1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3'-5'-exoribonuclease activity [GO:0000175]; nucleic acid binding [GO:0003676]; nucleotide binding [GO:0000166]; ribonuclease D activity [GO:0033890]; tRNA 3'-end processing [GO:0042780]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 3'-5' exonuclease activity [GO:0008408]; 5'-3' exonuclease activity [GO:0008409]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]	tRNA 3'-end processing [GO:0042780]	base-excision repair [GO:0006284]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	3'-5'-exoribonuclease activity [GO:0000175]; nucleic acid binding [GO:0003676]; nucleotide binding [GO:0000166]; ribonuclease D activity [GO:0033890]	3'-5' exonuclease activity [GO:0008408]; 5'-3' exonuclease activity [GO:0008409]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1yt9b__d4ybfa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]; proteolysis [GO:0006508]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1ytba1_d1pczb1__1	Fungi		Ascomycota	Euryarchaeota	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	DNA-templated transcription, initiation [GO:0006352]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]		chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1ytba1_d3cwub2__1	Fungi		Ascomycota	Proteobacteria	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1ytbb1_d3cw7a2__1	Fungi		Ascomycota	Proteobacteria	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d1ytda1_d5hulc2__1			Euryarchaeota	Firmicutes	metal ion binding [GO:0046872]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nucleotide binding [GO:0000166]; NAD biosynthetic process [GO:0009435]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]			metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nucleotide binding [GO:0000166]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1ytda2_d2b7na1__1			Euryarchaeota	Proteobacteria	metal ion binding [GO:0046872]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nucleotide binding [GO:0000166]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nucleotide binding [GO:0000166]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1ytea1_d3paja1__1			Euryarchaeota	Proteobacteria	metal ion binding [GO:0046872]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nucleotide binding [GO:0000166]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; quinolinate catabolic process [GO:0034213]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nucleotide binding [GO:0000166]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d1ytgb__d3apre___1		Fungi		Mucoromycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d1ytha__d2ieoa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1ytla1_d1ovmc1__1			Euryarchaeota	Proteobacteria	methanogenesis, from acetate [GO:0019385]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; auxin biosynthetic process [GO:0009851]	methanogenesis, from acetate [GO:0019385]	auxin biosynthetic process [GO:0009851]				indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1ytlc__d1roza___1		Metazoa	Euryarchaeota	Chordata	methanogenesis, from acetate [GO:0019385]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; deoxyhypusine synthase activity [GO:0034038]; identical protein binding [GO:0042802]; peptidyl-lysine modification to peptidyl-hypusine [GO:0008612]; positive regulation of cell population proliferation [GO:0008284]; spermidine metabolic process [GO:0008216]; translation [GO:0006412]	methanogenesis, from acetate [GO:0019385]	peptidyl-lysine modification to peptidyl-hypusine [GO:0008612]; positive regulation of cell population proliferation [GO:0008284]; spermidine metabolic process [GO:0008216]; translation [GO:0006412]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		deoxyhypusine synthase activity [GO:0034038]; identical protein binding [GO:0042802]
d1ytta__d4gj0a___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d1yttb__d2py2f___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	metal ion binding [GO:0046872]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]		collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]		calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]
d1ytva__d2v25b___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell surface [GO:0009986]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cell surface [GO:0009986]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	
d1ytva__d4n8ya___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	outer membrane-bounded periplasmic space [GO:0030288]; transmembrane transport [GO:0055085]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	
d1ytwa__d5kada1__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	pathogenesis [GO:0009405]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	extracellular region [GO:0005576]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1yu1a2_d2iouf2__1					virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	virus tail, fiber [GO:0098024]	virus tail, fiber [GO:0098024]		
d1yu3a2_d2ioub2__1					virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	virus tail, fiber [GO:0098024]	virus tail, fiber [GO:0098024]		
d1yu3a2_d3alsb___1		Metazoa		Echinodermata	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	metal ion binding [GO:0046872]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]		virus tail, fiber [GO:0098024]			metal ion binding [GO:0046872]
d1yu4a2_d3bx4c___1		Metazoa		Chordata	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	regulation of cytokine activity [GO:0060300]	virus tail, fiber [GO:0098024]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1yu4b2_d5b1xd1__1		Metazoa		Chordata	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; CD8-positive, alpha-beta T cell activation [GO:0036037]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; negative regulation of tumor necrosis factor production [GO:0032720]; plasmacytoid dendritic cell antigen processing and presentation [GO:0002470]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; CD8-positive, alpha-beta T cell activation [GO:0036037]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; negative regulation of tumor necrosis factor production [GO:0032720]; plasmacytoid dendritic cell antigen processing and presentation [GO:0002470]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	virus tail, fiber [GO:0098024]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]
d1yu4c2_d2iouc2__1					virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	virus tail, fiber [GO:0098024]	virus tail, fiber [GO:0098024]		
d1yu5x__d5vnta___1	Metazoa	Viridiplantae	Chordata	Streptophyta	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; cytoplasmic streaming [GO:0099636]; response to abscisic acid [GO:0009737]; root hair elongation [GO:0048767]	actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; cytoplasmic streaming [GO:0099636]; response to abscisic acid [GO:0009737]; root hair elongation [GO:0048767]	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]
d1yu6a__d1gtg1___1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]		serine-type endopeptidase inhibitor activity [GO:0004867]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1yuha2_d5n4gl1__1												
d1yuhh2_d2c1oa2__1		Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d1yuma__d5ekda___1		Metazoa	Proteobacteria	Chordata	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; mitochondrial tryptophanyl-tRNA aminoacylation [GO:0070183]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]; vasculogenesis [GO:0001570]	NAD biosynthetic process [GO:0009435]	mitochondrial tryptophanyl-tRNA aminoacylation [GO:0070183]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]; vasculogenesis [GO:0001570]		cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d1yumc__d5h7xa___1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	NAD biosynthetic process [GO:0009435]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1yumd__d1n2ja___1			Proteobacteria	Actinobacteria	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]; beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	NAD biosynthetic process [GO:0009435]	beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]		cytosol [GO:0005829]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]
d1yuph__d5d8ja1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]		brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d1yuta__d2oy6c___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]		cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	
d1yuwa2_d1bupa2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d1yuwa2_d4fwsa2__1	Metazoa		Chordata	Proteobacteria	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]; L-threonine catabolic process to propionate [GO:0070689]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	L-threonine catabolic process to propionate [GO:0070689]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]
d1yuwa3_d3bf1d1__1	Metazoa		Chordata	Thermotogae	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	coenzyme A biosynthetic process [GO:0015937]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d1yuxb1_d1xu5b___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]		cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1yuzb1_d3bvka1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d1yv1a1_d1jkva___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]			cytoplasm [GO:0005737]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]
d1yv9a1_d3zi4a___1			Firmicutes	Firmicutes	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; beta-phosphoglucomutase activity [GO:0008801]; hydrolase activity [GO:0016787]; magnesium ion binding [GO:0000287]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		cytoplasm [GO:0005737]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	beta-phosphoglucomutase activity [GO:0008801]; hydrolase activity [GO:0016787]; magnesium ion binding [GO:0000287]
d1yv9b2_d3e8mb___1			Firmicutes	Bacteroidetes	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]			hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d1yvda1_d4urxr1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; late endosome [GO:0005770]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; endocytosis [GO:0006897]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; Rab protein signal transduction [GO:0032482]; regulation of vesicle size [GO:0097494]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	endocytosis [GO:0006897]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; Rab protein signal transduction [GO:0032482]; regulation of vesicle size [GO:0097494]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	actin cytoskeleton [GO:0015629]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; late endosome [GO:0005770]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; ruffle [GO:0001726]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d1yvei2_d1f17b2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d1yvej2_d3etgb2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	chloroplast [GO:0009507]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1yvha1_d2bcba___1	Metazoa	Metazoa	Chordata	Chordata	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]		cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]
d1yvma__d3mr1b1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]
d1yvna1_d5nckb1__1	Metazoa		Chordata	Fusobacteria	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	N-acylmannosamine kinase activity [GO:0009384]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]		actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]		actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	N-acylmannosamine kinase activity [GO:0009384]
d1yvqa__d3g4ua___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1yvqb__d2mgea___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d1ywaa__d3rswb___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	vasodilation [GO:0042311]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]
d1ywaa__d3zq3d___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	small molecule binding [GO:0036094]	vasodilation [GO:0042311]		extracellular region [GO:0005576]		histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	small molecule binding [GO:0036094]
d1ywda__d4zhhb___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	vasodilation [GO:0042311]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1ywxa1_d1xn9a___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	structural constituent of ribosome [GO:0003735]	structural constituent of ribosome [GO:0003735]
d1yx9a__d2qnpb___1	Metazoa		Chordata		extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1yxca__d5dbud___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]	deoxyribose-phosphate aldolase activity [GO:0004139]
d1yxda__d4bk9c___1			Proteobacteria		cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytosol [GO:0005829]		4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]	
d1yxka__d2bpea1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d1yxka__d4pdcc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; MHC class I protein binding [GO:0042288]; MHC class Ib receptor activity [GO:0032394]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]	blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	carbohydrate binding [GO:0030246]; MHC class Ib receptor activity [GO:0032394]; MHC class I protein binding [GO:0042288]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]
d1yxkb__d2ridc1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d1yxkb__d3ccka___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cellular response to drug [GO:0035690]	blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	cellular response to drug [GO:0035690]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]
d1yxwa1_d1w6pb___1		Metazoa	Firmicutes	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	negative regulation of neurotransmitter secretion [GO:0046929]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d1yxwa2_d3qydb___1		Viridiplantae	Firmicutes	Streptophyta	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	serine-type endopeptidase inhibitor activity [GO:0004867]	negative regulation of neurotransmitter secretion [GO:0046929]		clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1yy7b1_d2obka___1			Proteobacteria	Proteobacteria								
d1yy7b2_d4topa2__1		Viridiplantae	Proteobacteria	Streptophyta		glutathione transferase activity [GO:0004364]						glutathione transferase activity [GO:0004364]
d1yy9a1_d3b2ua1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d1yy9a2_d3kj4a___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; presynapse [GO:0098793]; chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; Roundabout binding [GO:0048495]; signaling receptor activity [GO:0038023]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; presynapse [GO:0098793]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; Roundabout binding [GO:0048495]; signaling receptor activity [GO:0038023]
d1yy9c1_d2ny5l2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1yyfc1_d5fg7s___1		Fungi	Firmicutes	Ascomycota	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1yyfd1_d4qwic___1		Fungi	Firmicutes	Ascomycota	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1yyha1_d3twxb1__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transmembrane signaling receptor activity [GO:0004888]; animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral genome replication [GO:0045070]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; regulation of transcription, DNA-templated [GO:0006355]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; in utero embryonic development [GO:0001701]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transmembrane signaling receptor activity [GO:0004888]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]
d1yyll1_d1dqqd2__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1yylr2_d4hepg___1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	virus tail, baseplate [GO:0098025]	structural molecule activity [GO:0005198]	
d1yymh1_d2uwea1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1yymh2_d4y4hc1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	structural molecule activity [GO:0005198]	
d1yyml2_d4x7ed1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d1yymr1_d1jguh2__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d1yymr1_d2f5ah1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d1yyna1_d2zgsb___1		Fungi	Firmicutes	Basidiomycota	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	negative regulation of neurotransmitter secretion [GO:0046929]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d1yyna2_d4fvvb2__1			Firmicutes	Firmicutes	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]	negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]
d1yypa1_d1jqla1__1				Proteobacteria	host cell nucleus [GO:0042025]; virion [GO:0019012]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	host cell nucleus [GO:0042025]; virion [GO:0019012]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d1yyqa__d2q9zb___1	Fungi	Fungi	Ascomycota	Ascomycota	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]			metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]
d1yyqb__d2ps5b___1	Fungi	Fungi	Ascomycota	Ascomycota	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]			metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]
d1yysb__d1yyua___1	Fungi	Fungi	Ascomycota	Ascomycota	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]			metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]
d1yyta__d3wcjf___1	Fungi	Metazoa	Ascomycota	Chordata	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	sesquiterpenoid biosynthetic process [GO:0016106]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d1yyy1__d1p9ud___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1yz1b2_d2kzna1__1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; nucleus [GO:0005634]; spindle pole [GO:0000922]; calcium ion binding [GO:0005509]; RNA binding [GO:0003723]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; regulation of apoptotic process [GO:0042981]; response to virus [GO:0009615]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; regulation of apoptotic process [GO:0042981]; response to virus [GO:0009615]	protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; nucleus [GO:0005634]; spindle pole [GO:0000922]		calcium ion binding [GO:0005509]; RNA binding [GO:0003723]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]
d1yz3a__d3ieid___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; C-terminal protein methylation [GO:0006481]; cellular protein modification process [GO:0006464]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cellular protein modification process [GO:0006464]; C-terminal protein methylation [GO:0006481]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	phenylethanolamine N-methyltransferase activity [GO:0004603]	protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d1yzga1_d2h1ld___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; trans-Golgi network [GO:0005802]; GTP binding [GO:0005525]; intracellular protein transport [GO:0006886]; protein localization to Golgi membrane [GO:1903292]; vesicle-mediated transport [GO:0016192]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	intracellular protein transport [GO:0006886]; protein localization to Golgi membrane [GO:1903292]; vesicle-mediated transport [GO:0016192]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; trans-Golgi network [GO:0005802]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	GTP binding [GO:0005525]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d1yzib__d2vmlb___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1yzka__d1t6nb___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; centriolar satellite [GO:0034451]; cleavage furrow [GO:0032154]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; multivesicular body [GO:0005771]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; postsynaptic recycling endosome [GO:0098837]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; Schaffer collateral - CA1 synapse [GO:0098685]; spindle pole [GO:0000922]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133]; vesicle [GO:0031982]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; microtubule binding [GO:0008017]; myosin V binding [GO:0031489]; syntaxin binding [GO:0019905]; amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; plasma membrane to endosome transport [GO:0048227]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-translational protein modification [GO:0043687]; protein localization to plasma membrane [GO:0072659]; Rab protein signal transduction [GO:0032482]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; renal water homeostasis [GO:0003091]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003]	cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; transcription export complex [GO:0000346]; ATP binding [GO:0005524]; ATP-dependent protein binding [GO:0043008]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-dependent ATPase activity [GO:0008186]; U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070]; liver development [GO:0001889]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; RNA export from nucleus [GO:0006405]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784]	amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; plasma membrane to endosome transport [GO:0048227]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-translational protein modification [GO:0043687]; protein localization to plasma membrane [GO:0072659]; Rab protein signal transduction [GO:0032482]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; renal water homeostasis [GO:0003091]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003]	liver development [GO:0001889]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; RNA export from nucleus [GO:0006405]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784]	axon [GO:0030424]; cell [GO:0005623]; centriolar satellite [GO:0034451]; cleavage furrow [GO:0032154]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; multivesicular body [GO:0005771]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; postsynaptic recycling endosome [GO:0098837]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; Schaffer collateral - CA1 synapse [GO:0098685]; spindle pole [GO:0000922]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; transcription export complex [GO:0000346]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; microtubule binding [GO:0008017]; myosin V binding [GO:0031489]; syntaxin binding [GO:0019905]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; ATP-dependent protein binding [GO:0043008]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; RNA helicase activity [GO:0003724]; U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070]
d1yzoa__d1goga1__1		Fungi		Ascomycota		extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]				extracellular region [GO:0005576]		galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]
d1yzqa1_d4xsga___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin V binding [GO:0031489]; protein domain specific binding [GO:0019904]; antigen processing and presentation [GO:0019882]; early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; minus-end-directed organelle transport along microtubule [GO:0072385]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine methylation [GO:0018125]; protein localization to Golgi apparatus [GO:0034067]; Rab protein signal transduction [GO:0032482]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; viral process [GO:0016032]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	antigen processing and presentation [GO:0019882]; early endosome to Golgi transport [GO:0034498]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; minus-end-directed organelle transport along microtubule [GO:0072385]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine methylation [GO:0018125]; protein localization to Golgi apparatus [GO:0034067]; Rab protein signal transduction [GO:0032482]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; viral process [GO:0016032]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin V binding [GO:0031489]; protein domain specific binding [GO:0019904]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d1yzxb__d4mcua1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cell [GO:0005623]; periplasmic space [GO:0042597]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d1z01a1_d5klve2__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d1z01c2_d2yfji2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1z01d2_d2vjgb___1			Proteobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]						2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	
d1z01e2_d2de5c2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]		carbazole catabolic process [GO:0046232]			2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]
d1z01f2_d2xr8u2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d1z02e1_d1kyop1__1		Fungi	Proteobacteria	Ascomycota	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1z02f1_d2bmoa1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; cellular metabolic process [GO:0044237]		cellular metabolic process [GO:0044237]			2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1z03a1_d1kyoe1__1		Fungi	Proteobacteria	Ascomycota	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1z03a1_d4hkva1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	dioxygenase activity [GO:0051213]
d1z03a2_d4hm3a2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	dioxygenase activity [GO:0051213]
d1z03b1_d4hm4a1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	dioxygenase activity [GO:0051213]
d1z03b2_d2gbxc2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]		cellular aromatic compound metabolic process [GO:0006725]			2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	dioxygenase activity [GO:0051213]
d1z03d2_d1fm4a___1		Viridiplantae	Proteobacteria	Streptophyta	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d1z03d2_d1uuwa2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	dioxygenase activity [GO:0051213]
d1z03e2_d2de6c2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]		carbazole catabolic process [GO:0046232]			2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]
d1z03e2_d2psob___1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; mitochondrial membrane [GO:0031966]; GTPase activator activity [GO:0005096]; lipid binding [GO:0008289]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]		endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]		cytosol [GO:0005829]; lipid droplet [GO:0005811]; mitochondrial membrane [GO:0031966]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	GTPase activator activity [GO:0005096]; lipid binding [GO:0008289]
d1z03f1_d2hmma1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	dioxygenase activity [GO:0051213]
d1z03f2_d3gcfm2__1			Proteobacteria	Actinobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d1z05a3_d1deja2__1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]		actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d1z09b__d5y39g___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; membrane [GO:0016020]; microtubule [GO:0005874]; dynein intermediate chain binding [GO:0045505]; microtubule motor activity [GO:0003777]; intraciliary transport involved in cilium assembly [GO:0035735]; microtubule-based movement [GO:0007018]; visual behavior [GO:0007632]	endosome membrane [GO:0010008]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; Ragulator complex [GO:0071986]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; guanyl-nucleotide exchange factor activity [GO:0005085]; molecular adaptor activity [GO:0060090]; activation of MAPKK activity [GO:0000186]; cell cycle arrest [GO:0007050]; cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; MAPK cascade [GO:0000165]; neutrophil degranulation [GO:0043312]; positive regulation of TOR signaling [GO:0032008]; regulation of cell growth [GO:0001558]; regulation of macroautophagy [GO:0016241]	intraciliary transport involved in cilium assembly [GO:0035735]; microtubule-based movement [GO:0007018]; visual behavior [GO:0007632]	activation of MAPKK activity [GO:0000186]; cell cycle arrest [GO:0007050]; cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; MAPK cascade [GO:0000165]; neutrophil degranulation [GO:0043312]; positive regulation of TOR signaling [GO:0032008]; regulation of cell growth [GO:0001558]; regulation of macroautophagy [GO:0016241]	centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; membrane [GO:0016020]; microtubule [GO:0005874]	endosome membrane [GO:0010008]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; Ragulator complex [GO:0071986]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	dynein intermediate chain binding [GO:0045505]; microtubule motor activity [GO:0003777]	guanyl-nucleotide exchange factor activity [GO:0005085]; molecular adaptor activity [GO:0060090]
d1z0ha1_d1is3a___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	carbohydrate binding [GO:0030246]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]		lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	carbohydrate binding [GO:0030246]
d1z0ha1_d4jraa1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1z0hb2_d1xg6a1__1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	serine-type endopeptidase inhibitor activity [GO:0004867]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]		lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1z0kc__d1a5ta2__1	Metazoa		Chordata	Proteobacteria	anchored component of synaptic vesicle membrane [GO:0098993]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; insulin-responsive compartment [GO:0032593]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic recycling endosome [GO:0098837]; recycling endosome membrane [GO:0055038]; vesicle [GO:0031982]; ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ionotropic glutamate receptor binding [GO:0035255]; syntaxin binding [GO:0019905]; antigen processing and presentation [GO:0019882]; intracellular protein transport [GO:0006886]; phosphatidylinositol biosynthetic process [GO:0006661]; Rab protein signal transduction [GO:0032482]; regulation of endocytosis [GO:0030100]	DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA-dependent DNA replication [GO:0006261]	antigen processing and presentation [GO:0019882]; intracellular protein transport [GO:0006886]; phosphatidylinositol biosynthetic process [GO:0006661]; Rab protein signal transduction [GO:0032482]; regulation of endocytosis [GO:0030100]	DNA-dependent DNA replication [GO:0006261]	anchored component of synaptic vesicle membrane [GO:0098993]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; insulin-responsive compartment [GO:0032593]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic recycling endosome [GO:0098837]; recycling endosome membrane [GO:0055038]; vesicle [GO:0031982]	DNA polymerase III complex [GO:0009360]	ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ionotropic glutamate receptor binding [GO:0035255]; syntaxin binding [GO:0019905]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d1z0mc__d4yeeh1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; fatty acid biosynthetic process [GO:0006633]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; regulation of catalytic activity [GO:0050790]	apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]	fatty acid biosynthetic process [GO:0006633]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; regulation of catalytic activity [GO:0050790]	fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]	protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]	enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]
d1z10a__d1gjma___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1z10a__d2ygxb___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]		arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1z10d__d3l63a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1z11c__d2fe6a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1z11c__d4ggva___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]		arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1z11d__d1t87b___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d1z18a__d1efab2__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; isoleucine transport [GO:0015818]; leucine transport [GO:0015820]; valine transport [GO:0015829]	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	isoleucine transport [GO:0015818]; leucine transport [GO:0015820]; valine transport [GO:0015829]	negative regulation of transcription, DNA-templated [GO:0045892]	outer membrane-bounded periplasmic space [GO:0030288]	cytosol [GO:0005829]		bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]
d1z1ea1_d1dlva1__1	Viridiplantae		Streptophyta	Proteobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	biosynthetic process [GO:0009058]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d1z1fa1_d4jd3d1__1	Viridiplantae		Streptophyta	Actinobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	polyketide synthase complex [GO:0034081]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		polyketide synthase complex [GO:0034081]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1z1jb__d3aw0a___1					cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1z1wa1_d3fh7a1__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1z1wa2_d1bm6a___1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d1z22a1_d3oehw2__1	Metazoa	Fungi	Chordata	Ascomycota	autophagosome [GO:0005776]; cell junction [GO:0030054]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; autophagosome assembly [GO:0000045]; cellular defense response [GO:0006968]; cilium assembly [GO:0060271]; craniofacial suture morphogenesis [GO:0097094]; dorsal/ventral neural tube patterning [GO:0021904]; embryonic digit morphogenesis [GO:0042733]; GTP metabolic process [GO:0046039]; intracellular protein transport [GO:0006886]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of proteolysis [GO:0045861]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; Rab protein signal transduction [GO:0032482]; regulation of smoothened signaling pathway [GO:0008589]; signal transduction [GO:0007165]; spinal cord dorsal/ventral patterning [GO:0021513]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	autophagosome assembly [GO:0000045]; cellular defense response [GO:0006968]; cilium assembly [GO:0060271]; craniofacial suture morphogenesis [GO:0097094]; dorsal/ventral neural tube patterning [GO:0021904]; embryonic digit morphogenesis [GO:0042733]; GTP metabolic process [GO:0046039]; intracellular protein transport [GO:0006886]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of proteolysis [GO:0045861]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; Rab protein signal transduction [GO:0032482]; regulation of smoothened signaling pathway [GO:0008589]; signal transduction [GO:0007165]; spinal cord dorsal/ventral patterning [GO:0021513]	ATP synthesis coupled proton transport [GO:0015986]	autophagosome [GO:0005776]; cell junction [GO:0030054]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d1z2ea__d2feka___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; arsenate reductase (thioredoxin) activity [GO:0030612]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]	protein tyrosine phosphatase activity [GO:0004725]; colanic acid biosynthetic process [GO:0009242]	response to arsenic-containing substance [GO:0046685]	colanic acid biosynthetic process [GO:0009242]	cytoplasm [GO:0005737]		arsenate reductase (thioredoxin) activity [GO:0030612]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d1z2lb2_d1cg2b2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; allantoate deiminase activity [GO:0047652]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; allantoin assimilation pathway [GO:0009442]; purine nucleobase metabolic process [GO:0006144]	carboxypeptidase activity [GO:0004180]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]	allantoin assimilation pathway [GO:0009442]; purine nucleobase metabolic process [GO:0006144]		cytoplasm [GO:0005737]		allantoate deiminase activity [GO:0047652]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	carboxypeptidase activity [GO:0004180]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]
d1z2ua1_d3obua1__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	chromosome [GO:0005694]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]; autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	chromosome [GO:0005694]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]
d1z2wb__d5gtua___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer complex [GO:0030904]; retromer, cargo-selective complex [GO:0030906]; metal ion binding [GO:0046872]; endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]	cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; retromer complex [GO:0030904]; retromer, cargo-selective complex [GO:0030906]; metal ion binding [GO:0046872]; endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]	endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer, cargo-selective complex [GO:0030906]; retromer complex [GO:0030904]	cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; retromer, cargo-selective complex [GO:0030906]; retromer complex [GO:0030904]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d1z2xa__d2dxnb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer complex [GO:0030904]; retromer, cargo-selective complex [GO:0030906]; metal ion binding [GO:0046872]; endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]		cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer, cargo-selective complex [GO:0030906]; retromer complex [GO:0030904]		metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1z32x1_d1xd0a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1z3da__d4gpra1__1	Metazoa		Nematoda (roundworms)		HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; ubiquitin conjugating enzyme complex [GO:0031371]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-dependent protein catabolic process [GO:0006511]	DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	ubiquitin-dependent protein catabolic process [GO:0006511]	HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; ubiquitin conjugating enzyme complex [GO:0031371]		ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]
d1z3eb1_d1doqa___1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]; transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]		DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]
d1z3gh1_d5eiil1__1		Fungi	Apicomplexa	Ascomycota	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleus [GO:0005634]; histone binding [GO:0042393]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H2B ubiquitination [GO:0033523]; nucleosome disassembly [GO:0006337]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of gene expression [GO:0010468]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]		chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H2B ubiquitination [GO:0033523]; nucleosome disassembly [GO:0006337]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of gene expression [GO:0010468]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]	histone binding [GO:0042393]
d1z3gi1_d1nldl1__1			Apicomplexa		cell surface [GO:0009986]; integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]				cell surface [GO:0009986]; integral component of membrane [GO:0016021]		calcium ion binding [GO:0005509]	
d1z3gi1_d3mv8b1__1		Metazoa	Apicomplexa	Chordata	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	calcium ion binding [GO:0005509]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1z3gl1_d5f1kc___1		Metazoa	Apicomplexa	Chordata	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]		apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	calcium ion binding [GO:0005509]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d1z3gl2_d1cr9l2__1			Apicomplexa		cell surface [GO:0009986]; integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]				cell surface [GO:0009986]; integral component of membrane [GO:0016021]		calcium ion binding [GO:0005509]	
d1z3ix1_d1wp9f1__1	Metazoa		Chordata	Euryarchaeota	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; DNA-dependent ATPase activity [GO:0008094]; metal ion binding [GO:0046872]; double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; reciprocal meiotic recombination [GO:0007131]	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; DNA repair [GO:0006281]	double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; reciprocal meiotic recombination [GO:0007131]	DNA repair [GO:0006281]	nucleus [GO:0005634]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA translocase activity [GO:0015616]; metal ion binding [GO:0046872]	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]
d1z3ix2_d1vecb___1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; DNA-dependent ATPase activity [GO:0008094]; metal ion binding [GO:0046872]; double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; reciprocal meiotic recombination [GO:0007131]	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; reciprocal meiotic recombination [GO:0007131]	cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	nucleus [GO:0005634]	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA translocase activity [GO:0015616]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]
d1z3ja2_d1l3fe___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1z3qa__d3v7va___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta		cytoplasmic vesicle [GO:0031410]				cytoplasmic vesicle [GO:0031410]		
d1z3sa1_d1n73f1__1	Metazoa	Metazoa	Chordata	Chordata	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	fibrinogen complex [GO:0005577]	metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]	metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]
d1z3sb1_d2j1gc___1	Metazoa	Metazoa	Chordata	Chordata	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d1z3ud1_d1fzce1__1	Metazoa	Metazoa	Chordata	Chordata	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d1z3va__d4yz4b1__1	Fungi		Basidiomycota	Firmicutes	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d1z3va__d6cela___1	Fungi	Fungi	Basidiomycota	Ascomycota	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d1z4aa__d2fjcd___1			Thermotogae	Spirochaetes	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1z4aa__d3isfc___1			Thermotogae	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1z4ab__d4tofa___1			Thermotogae	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1z4ae__d2xkqb___1			Thermotogae	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d1z4af__d3qb9b___1			Thermotogae	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1z4ag__d3a9qw___1		Viridiplantae	Thermotogae	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1z4ag__d4tobv___1			Thermotogae	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1z4eb__d1m1dc___1		Fungi	Firmicutes	Ascomycota	N-acetyltransferase activity [GO:0008080]	CENP-A containing nucleosome [GO:0043505]; nuclear nucleosome [GO:0000788]; nucleus [GO:0005634]; replication fork protection complex [GO:0031298]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin assembly or disassembly [GO:0006333]; global genome nucleotide-excision repair [GO:0070911]; rRNA transcription [GO:0009303]; sexual sporulation resulting in formation of a cellular spore [GO:0043935]		chromatin assembly or disassembly [GO:0006333]; global genome nucleotide-excision repair [GO:0070911]; rRNA transcription [GO:0009303]; sexual sporulation resulting in formation of a cellular spore [GO:0043935]		CENP-A containing nucleosome [GO:0043505]; nuclear nucleosome [GO:0000788]; nucleus [GO:0005634]; replication fork protection complex [GO:0031298]	N-acetyltransferase activity [GO:0008080]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d1z4ia1_d1fezd___1	Metazoa		Chordata	Firmicutes	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	organic phosphonate catabolic process [GO:0019700]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]
d1z4ja__d5alea1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d1z4ka__d3vayb___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1z4la__d4nfla1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]
d1z4qa__d3qu4h___1	Metazoa		Chordata	Bacteroidetes	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]
d1z4ra1_d1i1dd1__1	Metazoa	Fungi	Chordata	Ascomycota	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; mitotic spindle [GO:0072686]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; STAGA complex [GO:0030914]; transcription factor TFTC complex [GO:0033276]; chromatin binding [GO:0003682]; H3 histone acetyltransferase activity [GO:0010484]; histone acetyltransferase activity [GO:0004402]; histone acetyltransferase activity (H4-K12 specific) [GO:0043997]; histone deacetylase binding [GO:0042826]; histone succinyltransferase activity [GO:0106078]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein phosphatase binding [GO:0019903]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; alpha-tubulin acetylation [GO:0071929]; cell population proliferation [GO:0008283]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; cytokine production [GO:0001816]; heart development [GO:0007507]; histone deubiquitination [GO:0016578]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; histone succinylation [GO:0106077]; in utero embryonic development [GO:0001701]; internal peptidyl-lysine acetylation [GO:0018393]; intracellular distribution of mitochondria [GO:0048312]; limb development [GO:0060173]; long-term memory [GO:0007616]; metencephalon development [GO:0022037]; midbrain development [GO:0030901]; multicellular organism growth [GO:0035264]; negative regulation of centriole replication [GO:0046600]; neural tube closure [GO:0001843]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell projection organization [GO:0031346]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; regulation of protein stability [GO:0031647]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell activation [GO:0050863]; regulation of transcription by RNA polymerase II [GO:0006357]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; somitogenesis [GO:0001756]; telencephalon development [GO:0021537]; viral process [GO:0016032]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	alpha-tubulin acetylation [GO:0071929]; cell population proliferation [GO:0008283]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; cytokine production [GO:0001816]; heart development [GO:0007507]; histone deubiquitination [GO:0016578]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; histone succinylation [GO:0106077]; internal peptidyl-lysine acetylation [GO:0018393]; intracellular distribution of mitochondria [GO:0048312]; in utero embryonic development [GO:0001701]; limb development [GO:0060173]; long-term memory [GO:0007616]; metencephalon development [GO:0022037]; midbrain development [GO:0030901]; multicellular organism growth [GO:0035264]; negative regulation of centriole replication [GO:0046600]; neural tube closure [GO:0001843]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell projection organization [GO:0031346]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; regulation of protein stability [GO:0031647]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell activation [GO:0050863]; regulation of transcription by RNA polymerase II [GO:0006357]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; somitogenesis [GO:0001756]; telencephalon development [GO:0021537]; viral process [GO:0016032]	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; mitotic spindle [GO:0072686]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; STAGA complex [GO:0030914]; transcription factor TFTC complex [GO:0033276]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; H3 histone acetyltransferase activity [GO:0010484]; histone acetyltransferase activity [GO:0004402]; histone acetyltransferase activity (H4-K12 specific) [GO:0043997]; histone deacetylase binding [GO:0042826]; histone succinyltransferase activity [GO:0106078]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein phosphatase binding [GO:0019903]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]	glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]
d1z4sa1_d2afgd___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d1z4wa__d3cl2f___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; viral budding from plasma membrane [GO:0046761]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral budding from plasma membrane [GO:0046761]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1z4xa__d1usxa___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; viral budding from plasma membrane [GO:0046761]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	viral budding from plasma membrane [GO:0046761]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]
d1z52a1_d4j6jc___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d1z52b1_d4n35a___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]		antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d1z54a1_d1s5ub___1			Deinococcus-Thermus	Proteobacteria	hydrolase activity [GO:0016787]	plasma membrane [GO:0005886]; acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]; lipid metabolic process [GO:0006629]		lipid metabolic process [GO:0006629]		plasma membrane [GO:0005886]	hydrolase activity [GO:0016787]	acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]
d1z54a1_d1vi8h1__1			Deinococcus-Thermus	Proteobacteria	hydrolase activity [GO:0016787]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]; menaquinone biosynthetic process [GO:0009234]		menaquinone biosynthetic process [GO:0009234]		cytosol [GO:0005829]	hydrolase activity [GO:0016787]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]
d1z5aa2_d1kija1__1			Crenarchaeota	Deinococcus-Thermus	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]		chromosome [GO:0005694]; cytoplasm [GO:0005737]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; metal ion binding [GO:0046872]
d1z5aa2_d3p76a1__1			Crenarchaeota	Aquificae	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	lipid A biosynthetic process [GO:0009245]			ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d1z5ab2_d2hhhe1__1			Crenarchaeota	Deinococcus-Thermus	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	translation [GO:0006412]		ribosome [GO:0005840]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1z5ab3_d4asaa___1		Fungi	Crenarchaeota	Ascomycota	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]
d1z5cb1_d3sasa2__1			Crenarchaeota	Firmicutes	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]			ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]
d1z5gd__d2autb___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]			outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]
d1z5ha1_d3ftsa1__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1z5ha2_d5niec2__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1z5hb2_d4fyta2__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]		angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1z5hb2_d5n3wa2__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1z5hb3_d4homa3__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]		angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d1z5lb__d5ksab2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1z5ld__d5lz0a1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1z5ua__d1rmta___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]			outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]
d1z5ud__d1l8lb___1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; phosphoserine phosphatase activity [GO:0004647]; protein homodimerization activity [GO:0042803]; dephosphorylation [GO:0016311]; in utero embryonic development [GO:0001701]; L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563]; response to mechanical stimulus [GO:0009612]; response to nutrient levels [GO:0031667]; response to testosterone [GO:0033574]		dephosphorylation [GO:0016311]; in utero embryonic development [GO:0001701]; L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563]; response to mechanical stimulus [GO:0009612]; response to nutrient levels [GO:0031667]; response to testosterone [GO:0033574]	outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; phosphoserine phosphatase activity [GO:0004647]; protein homodimerization activity [GO:0042803]
d1z5ye1_d1ewxa___1			Proteobacteria		cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]	disulfide oxidoreductase activity [GO:0015036]	
d1z66a__d3p54a2__1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1z66a__d5omza___1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1z69c__d1bslb___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity [GO:0018537]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	alkanal monooxygenase (FMN-linked) activity [GO:0047646]; bioluminescence [GO:0008218]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	bioluminescence [GO:0008218]	cytoplasm [GO:0005737]		coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity [GO:0018537]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	alkanal monooxygenase (FMN-linked) activity [GO:0047646]
d1z69d__d1fvpa___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity [GO:0018537]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	alkanal monooxygenase (FMN-linked) activity [GO:0047646]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]		cytoplasm [GO:0005737]		coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity [GO:0018537]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	alkanal monooxygenase (FMN-linked) activity [GO:0047646]
d1z6db__d11bgb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]		RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d1z6ea__d5gsob___1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	cysteine-type endopeptidase activity [GO:0004197]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]
d1z6fa1_d3itaa2__1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; beta-lactamase activity [GO:0008800]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall macromolecule metabolic process [GO:0044036]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan metabolic process [GO:0000270]; regulation of cell shape [GO:0008360]	integral component of plasma membrane [GO:0005887]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to drug [GO:0042493]	cell wall macromolecule metabolic process [GO:0044036]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan metabolic process [GO:0000270]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to drug [GO:0042493]	integral component of plasma membrane [GO:0005887]	integral component of plasma membrane [GO:0005887]	beta-lactamase activity [GO:0008800]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]	carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]
d1z6ga__d1s6ta___1			Apicomplexa		cytosol [GO:0005829]; guanylate kinase activity [GO:0004385]; dGDP phosphorylation [GO:0006186]		dGDP phosphorylation [GO:0006186]		cytosol [GO:0005829]		guanylate kinase activity [GO:0004385]	
d1z6jh__d4wxvb___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]
d1z6jt2_d1bqub2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]
d1z6od__d2jd69___1	Metazoa		Arthropoda	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d1z6oe__d4toal___1	Metazoa		Arthropoda	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1z6of__d4xgsc1__1	Metazoa		Arthropoda	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1z6oh__d4cybd___1	Metazoa		Arthropoda	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1z6oh__d5c6fa1__1	Metazoa		Arthropoda	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d1z6oj__d1jkvc___1	Metazoa		Arthropoda	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]
d1z6ol__d4m32a___1	Metazoa		Arthropoda	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d1z6on__d1fz4c___1	Metazoa		Arthropoda	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1z6op__d4xkuc___1	Metazoa		Arthropoda	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1z6or__d3wnwi___1	Metazoa	Metazoa	Arthropoda	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1z6ov__d5d8qh___1	Metazoa		Arthropoda	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1z6ox__d4d8gb1__1	Metazoa		Arthropoda	Chlamydiae	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d1z6xb__d3peza1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; ruffle membrane [GO:0032587]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; epidermal growth factor receptor binding [GO:0005154]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; activation of phospholipase D activity [GO:0031584]; apical protein localization [GO:0045176]; brain development [GO:0007420]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular protein transport [GO:0006886]; learning [GO:0007612]; negative regulation of apoptotic process [GO:0043066]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein ADP-ribosylation [GO:0006471]; protein localization to cilium [GO:0061512]; regulation of postsynapse organization [GO:0099175]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to axon injury [GO:0048678]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192]		activation of phospholipase D activity [GO:0031584]; apical protein localization [GO:0045176]; brain development [GO:0007420]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular protein transport [GO:0006886]; learning [GO:0007612]; negative regulation of apoptotic process [GO:0043066]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein ADP-ribosylation [GO:0006471]; protein localization to cilium [GO:0061512]; regulation of postsynapse organization [GO:0099175]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to axon injury [GO:0048678]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; ruffle membrane [GO:0032587]		ARF guanyl-nucleotide exchange factor activity [GO:0005086]; epidermal growth factor receptor binding [GO:0005154]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	
d1z7eb2_d1nqtk1__1		Metazoa	Proteobacteria	Chordata	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1z7ec1_d4qpdb2__1		Metazoa	Proteobacteria	Chordata	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	cytoplasm [GO:0005737]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydrolase activity [GO:0016787]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; embryonic viscerocranium morphogenesis [GO:0048703]; gastrulation [GO:0007369]; heart development [GO:0007507]; neural crest cell migration [GO:0001755]; neuromast deposition [GO:0048885]; one-carbon metabolic process [GO:0006730]	lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; embryonic viscerocranium morphogenesis [GO:0048703]; gastrulation [GO:0007369]; heart development [GO:0007507]; neural crest cell migration [GO:0001755]; neuromast deposition [GO:0048885]; one-carbon metabolic process [GO:0006730]		cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydrolase activity [GO:0016787]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]
d1z7ec2_d4nbua___1			Proteobacteria	Firmicutes	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]				identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1z7ee2_d4rf4a___1			Proteobacteria	Firmicutes	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]				identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1z7ef1_d1fmtb1__1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	cytosol [GO:0005829]; methionyl-tRNA formyltransferase activity [GO:0004479]; charged-tRNA amino acid modification [GO:0019988]; conversion of methionyl-tRNA to N-formyl-methionyl-tRNA [GO:0071951]	lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	charged-tRNA amino acid modification [GO:0019988]; conversion of methionyl-tRNA to N-formyl-methionyl-tRNA [GO:0071951]		cytosol [GO:0005829]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]	methionyl-tRNA formyltransferase activity [GO:0004479]
d1z7ja__d3iwue___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d1z7nb1_d3nela2__1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; histidine biosynthetic process [GO:0000105]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	histidine biosynthetic process [GO:0000105]	aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]		aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d1z7nf1_d2y84b___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; histidine biosynthetic process [GO:0000105]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	histidine biosynthetic process [GO:0000105]		cytoplasm [GO:0005737]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1z7nf1_d5otab___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; histidine biosynthetic process [GO:0000105]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	histidine biosynthetic process [GO:0000105]	nitrogen compound transport [GO:0071705]	cytoplasm [GO:0005737]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]		ligand-gated ion channel activity [GO:0015276]
d1z7qf1_d4hnpj___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1z7qn1_d4qwsp___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1z7qn1_d5l69c___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d1z7xw__d2q4gy___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular exosome [GO:0070062]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	RNA phosphodiester bond hydrolysis [GO:0090501]	RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular exosome [GO:0070062]	extracellular exosome [GO:0070062]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]
d1z7zi1_d3u6rb___1	Metazoa		Chordata		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]		acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]	
d1z7zi4_d2vola2__1	Metazoa		Chordata		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]		acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]	
d1z84b2_d5kmca___1	Viridiplantae	Metazoa	Streptophyta	Chordata	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d1z88a1_d3hycb___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]	outer membrane-bounded periplasmic space [GO:0030288]		acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1z88c__d3umga___1			Proteobacteria	Actinobacteria	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	(S)-2-haloacid dehalogenase activity [GO:0018784]			outer membrane-bounded periplasmic space [GO:0030288]		acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	(S)-2-haloacid dehalogenase activity [GO:0018784]
d1z88d__d1k1eb___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]	outer membrane-bounded periplasmic space [GO:0030288]		acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d1z8fa__d4i1oe1__1		Metazoa	Actinobacteria	Chordata	cytosol [GO:0005829]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; guanylate kinase activity [GO:0004385]; magnesium ion binding [GO:0000287]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471]; phagophore assembly site membrane [GO:0034045]; transport vesicle [GO:0030133]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; autophagosome assembly [GO:0000045]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; positive regulation of glycoprotein metabolic process [GO:1903020]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; regulation of autophagosome assembly [GO:2000785]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; virion assembly [GO:0019068]		autophagosome assembly [GO:0000045]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; positive regulation of glycoprotein metabolic process [GO:1903020]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; regulation of autophagosome assembly [GO:2000785]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; virion assembly [GO:0019068]	cytosol [GO:0005829]	cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471]; phagophore assembly site membrane [GO:0034045]; transport vesicle [GO:0030133]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; guanylate kinase activity [GO:0004385]; magnesium ion binding [GO:0000287]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d1z8ga1_d2d2da___1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]; basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1z8ga2_d5jfba1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]; basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; scavenger receptor activity [GO:0005044]; virus receptor activity [GO:0001618]; acute-phase response [GO:0006953]	basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	acute-phase response [GO:0006953]	apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]	calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]	scavenger receptor activity [GO:0005044]; virus receptor activity [GO:0001618]
d1z8oa__d3cbdb___1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; erythromycin biosynthetic process [GO:1901115]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	erythromycin biosynthetic process [GO:1901115]; oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d1z8qa__d3t3sb___1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; erythromycin biosynthetic process [GO:1901115]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	erythromycin biosynthetic process [GO:1901115]; oxidation-reduction process [GO:0055114]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d1z8ta__d2eo8c___1			Euryarchaeota	Euryarchaeota	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d1z8td__d2ebja___1			Euryarchaeota	Deinococcus-Thermus	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d1z8ub__d2uunk___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d1z8xb__d4hpsc___1			Euryarchaeota	Proteobacteria	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d1z8yq1_d1g34a___1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]		host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]	
d1z8yr1_d4uonb___1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1z8yr1_d5fcrb___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; complement activation, alternative pathway [GO:0006957]; Notch signaling pathway [GO:0007219]; response to bacterium [GO:0009617]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	complement activation, alternative pathway [GO:0006957]; Notch signaling pathway [GO:0007219]; response to bacterium [GO:0009617]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular space [GO:0005615]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]	endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]
d1z8ys1_d5gpif___1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1z8yt1_d3htc.1__1		Metazoa		Annelida	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]		host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]	serine-type endopeptidase inhibitor activity [GO:0004867]
d1z91a1_d2fnpb___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d1z93a1_d3s97a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; carbonate dehydratase activity [GO:0004089]; nickel cation binding [GO:0016151]; phosphatase activity [GO:0016791]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; response to oxidative stress [GO:0006979]	anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]	bicarbonate transport [GO:0015701]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; response to oxidative stress [GO:0006979]	cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]	cytosol [GO:0005829]	anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]	carbonate dehydratase activity [GO:0004089]; nickel cation binding [GO:0016151]; phosphatase activity [GO:0016791]; zinc ion binding [GO:0008270]	carbohydrate binding [GO:0030246]
d1z93a1_d4z1ea___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; carbonate dehydratase activity [GO:0004089]; nickel cation binding [GO:0016151]; phosphatase activity [GO:0016791]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; response to oxidative stress [GO:0006979]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; response to oxidative stress [GO:0006979]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cytosol [GO:0005829]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	carbonate dehydratase activity [GO:0004089]; nickel cation binding [GO:0016151]; phosphatase activity [GO:0016791]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1z9aa__d5jgwd___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	oxidoreductase activity [GO:0016491]; D-xylose catabolic process [GO:0042843]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	D-xylose catabolic process [GO:0042843]				oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1z9cc__d2b0lc2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; GTP binding [GO:0005525]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]	DNA-binding transcription repressor activity [GO:0001217]; GTP binding [GO:0005525]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1z9cd__d2fbha1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; regulation of transcription, DNA-templated [GO:0006355]	DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]		DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]	DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]
d1z9ha2_d1ydka2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1z9hb2_d2ahea1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	actin cytoskeleton [GO:0015629]; apical part of cell [GO:0045177]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; centrosome [GO:0005813]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; microvillus [GO:0005902]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; chloride transport [GO:0006821]; endothelial cell morphogenesis [GO:0001886]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; fertilization [GO:0009566]; keratinocyte differentiation [GO:0030216]; multicellular organism growth [GO:0035264]; negative regulation of cell migration [GO:0030336]; regulation of cytoskeleton organization [GO:0051493]; regulation of ion transmembrane transport [GO:0034765]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; vacuolar acidification [GO:0007035]	cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; chloride transport [GO:0006821]; endothelial cell morphogenesis [GO:0001886]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; fertilization [GO:0009566]; keratinocyte differentiation [GO:0030216]; multicellular organism growth [GO:0035264]; negative regulation of cell migration [GO:0030336]; regulation of cytoskeleton organization [GO:0051493]; regulation of ion transmembrane transport [GO:0034765]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; vacuolar acidification [GO:0007035]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]	actin cytoskeleton [GO:0015629]; apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; centrosome [GO:0005813]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; microvillus [GO:0005902]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]	chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]
d1z9hd2_d1oyja2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione transferase activity [GO:0004364]
d1z9pb__d2sodg___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]		activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	periplasmic space [GO:0042597]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d1za2c1_d3e2pf1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d1za3a1_d2ol3l2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1za3h1_d1d5il2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1za3l1_d5dupl1__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]	host cell surface receptor binding [GO:0046789]
d1za5b1_d2goja1__1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1za6b1_d1f97a1__1	Metazoa	Metazoa	Chordata	Chordata		bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasmic vesicle [GO:0031410]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; actomyosin structure organization [GO:0031032]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; epithelial cell differentiation [GO:0030855]; establishment of endothelial intestinal barrier [GO:0090557]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]		actomyosin structure organization [GO:0031032]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; epithelial cell differentiation [GO:0030855]; establishment of endothelial intestinal barrier [GO:0090557]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]		bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cytoplasmic vesicle [GO:0031410]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]		integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]
d1za6b3_d2g75a1__1	Metazoa		Chordata									
d1za6c1_d1n4xi1__1	Metazoa	Metazoa	Chordata	Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		antigen binding [GO:0003823]
d1za6c2_d3cvhn___1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1za6e1_d1c12a1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1za6e2_d1sy6l2__1	Metazoa	Metazoa	Chordata	Chordata		alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]
d1za6e2_d4odsl1__1	Metazoa		Chordata									
d1za6f2_d5u16b___1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1za6f3_d4yhol1__1	Metazoa		Chordata									
d1za6g2_d1hcfy___1	Metazoa	Metazoa	Chordata	Chordata		axon [GO:0030424]; axon terminus [GO:0043679]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; brain-derived neurotrophic factor binding [GO:0048403]; brain-derived neurotrophic factor-activated receptor activity [GO:0060175]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of phospholipase C activity [GO:0007202]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cellular response to amino acid stimulus [GO:0071230]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; circadian rhythm [GO:0007623]; feeding behavior [GO:0007631]; glutamate secretion [GO:0014047]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuronal action potential propagation [GO:0019227]; neurotrophin TRK receptor signaling pathway [GO:0048011]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system neuron development [GO:0048935]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; retinal rod cell development [GO:0046548]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trans-synaptic signaling by neuropeptide, modulating synaptic transmission [GO:0099551]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]		activation of phospholipase C activity [GO:0007202]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cellular response to amino acid stimulus [GO:0071230]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; circadian rhythm [GO:0007623]; feeding behavior [GO:0007631]; glutamate secretion [GO:0014047]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neuronal action potential propagation [GO:0019227]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neurotrophin TRK receptor signaling pathway [GO:0048011]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system neuron development [GO:0048935]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; retinal rod cell development [GO:0046548]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trans-synaptic signaling by neuropeptide, modulating synaptic transmission [GO:0099551]; vasculogenesis [GO:0001570]		axon [GO:0030424]; axon terminus [GO:0043679]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]		ATP binding [GO:0005524]; brain-derived neurotrophic factor-activated receptor activity [GO:0060175]; brain-derived neurotrophic factor binding [GO:0048403]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d1za6g2_d2eytb2__1	Metazoa	Metazoa	Chordata	Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d1za6h1_d3or7a1__1	Metazoa		Chordata	Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d1za6h3_d3sy0b1__1	Metazoa		Chordata									
d1za7c__d1yc6z___1					T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]			T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1zabb__d2kema___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]	base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	cytosol [GO:0005829]	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]	cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1zabc__d2z3jb___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]	response to antibiotic [GO:0046677]	cytosol [GO:0005829]		cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d1zabd__d4g3md1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]		cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d1zaca__d4gplb2__1	Metazoa	Metazoa	Chordata	Chordata	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	troponin complex [GO:0005861]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]
d1zaga1_d5xajc1__1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]		collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	
d1zaga2_d3quya1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1zagb2_d1bx2a2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d1zagc1_d4d3cl2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1zahc__d1qo5l___1	Metazoa	Metazoa	Chordata	Chordata	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose binding [GO:0070061]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]; canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	I band [GO:0031674]; M band [GO:0031430]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]	fructose-bisphosphate aldolase activity [GO:0004332]	ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose binding [GO:0070061]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]
d1zaia__d1vr6a2__1	Metazoa		Chordata	Thermotogae	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	I band [GO:0031674]; M band [GO:0031430]		fructose-bisphosphate aldolase activity [GO:0004332]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]
d1zaid__d1adoc___1	Metazoa	Metazoa	Chordata	Chordata	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	I band [GO:0031674]; M band [GO:0031430]	I band [GO:0031674]; M band [GO:0031430]	fructose-bisphosphate aldolase activity [GO:0004332]	fructose-bisphosphate aldolase activity [GO:0004332]
d1zaid__d1gzga___1	Metazoa		Chordata	Proteobacteria	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]; heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	I band [GO:0031674]; M band [GO:0031430]	cytosol [GO:0005829]	fructose-bisphosphate aldolase activity [GO:0004332]	porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]
d1zanl2_d5d5mh1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1zapa__d3ekwb___1	Fungi		Ascomycota		extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d1zara1_d4omzg___1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein serine/threonine kinase activity [GO:0004674]	DNA-binding transcription factor activity [GO:0003700]					ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein serine/threonine kinase activity [GO:0004674]	DNA-binding transcription factor activity [GO:0003700]
d1zaua__d2q2ub2__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; DNA ligase (NAD+) activity [GO:0003911]; magnesium ion binding [GO:0000287]; base-excision repair, DNA ligation [GO:0006288]; DNA ligation [GO:0006266]; DNA replication [GO:0006260]	ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]	base-excision repair, DNA ligation [GO:0006288]; DNA ligation [GO:0006266]; DNA replication [GO:0006260]	DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		DNA ligase (NAD+) activity [GO:0003911]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]
d1zbbe1_d4h9pb___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1zbqa1_d1b26c1__1	Metazoa		Chordata	Thermotogae	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]; alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]		17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d1zbqb__d2pk3a___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]; alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	GDP-4-dehydro-6-deoxy-D-mannose reductase activity [GO:0033705]; oxidation-reduction process [GO:0055114]	alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]		17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]	GDP-4-dehydro-6-deoxy-D-mannose reductase activity [GO:0033705]
d1zbqe__d2ztld___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]; alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]		cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]		17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d1zc3c__d5mi3a1__1	Metazoa		Chordata		cell surface [GO:0009986]; cleavage furrow [GO:0032154]; cytoplasmic vesicle membrane [GO:0030659]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ATPase binding [GO:0051117]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; ubiquitin protein ligase binding [GO:0031625]; actin cytoskeleton reorganization [GO:0031532]; cell cycle [GO:0007049]; cell division [GO:0051301]; chemotaxis [GO:0006935]; exocytosis [GO:0006887]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane organization [GO:0061024]; membrane raft localization [GO:0051665]; neural tube closure [GO:0001843]; positive regulation of filopodium assembly [GO:0051491]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; signal transduction [GO:0007165]		actin cytoskeleton reorganization [GO:0031532]; cell cycle [GO:0007049]; cell division [GO:0051301]; chemotaxis [GO:0006935]; exocytosis [GO:0006887]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane organization [GO:0061024]; membrane raft localization [GO:0051665]; neural tube closure [GO:0001843]; positive regulation of filopodium assembly [GO:0051491]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; signal transduction [GO:0007165]		cell surface [GO:0009986]; cleavage furrow [GO:0032154]; cytoplasmic vesicle membrane [GO:0030659]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]		ATPase binding [GO:0051117]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; ubiquitin protein ligase binding [GO:0031625]	
d1zc4b1_d1y19j2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cleavage furrow [GO:0032154]; cytoplasmic vesicle membrane [GO:0030659]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ATPase binding [GO:0051117]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; ubiquitin protein ligase binding [GO:0031625]; actin cytoskeleton reorganization [GO:0031532]; cell cycle [GO:0007049]; cell division [GO:0051301]; chemotaxis [GO:0006935]; exocytosis [GO:0006887]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane organization [GO:0061024]; membrane raft localization [GO:0051665]; neural tube closure [GO:0001843]; positive regulation of filopodium assembly [GO:0051491]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; signal transduction [GO:0007165]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	actin cytoskeleton reorganization [GO:0031532]; cell cycle [GO:0007049]; cell division [GO:0051301]; chemotaxis [GO:0006935]; exocytosis [GO:0006887]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane organization [GO:0061024]; membrane raft localization [GO:0051665]; neural tube closure [GO:0001843]; positive regulation of filopodium assembly [GO:0051491]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; signal transduction [GO:0007165]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	cell surface [GO:0009986]; cleavage furrow [GO:0032154]; cytoplasmic vesicle membrane [GO:0030659]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	ATPase binding [GO:0051117]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; ubiquitin protein ligase binding [GO:0031625]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]
d1zc8y1_d4q7jb2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1zc8y1_d5vh6a2__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1zc8y3_d1veca___1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]		cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	cytoplasm [GO:0005737]	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]
d1zcca1_d3ptda___1			Proteobacteria	Firmicutes	phosphoric diester hydrolase activity [GO:0008081]; lipid metabolic process [GO:0006629]	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	lipid metabolic process [GO:0006629]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	phosphoric diester hydrolase activity [GO:0008081]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]
d1zcce__d2p76e1__1			Proteobacteria	Firmicutes	phosphoric diester hydrolase activity [GO:0008081]; lipid metabolic process [GO:0006629]	phosphoric diester hydrolase activity [GO:0008081]; lipid metabolic process [GO:0006629]	lipid metabolic process [GO:0006629]	lipid metabolic process [GO:0006629]			phosphoric diester hydrolase activity [GO:0008081]	phosphoric diester hydrolase activity [GO:0008081]
d1zccf__d5t9ce___1			Proteobacteria	Firmicutes	phosphoric diester hydrolase activity [GO:0008081]; lipid metabolic process [GO:0006629]	glycerophosphodiester phosphodiesterase activity [GO:0008889]; metal ion binding [GO:0046872]; glycerol metabolic process [GO:0006071]; lipid metabolic process [GO:0006629]	lipid metabolic process [GO:0006629]	glycerol metabolic process [GO:0006071]; lipid metabolic process [GO:0006629]			phosphoric diester hydrolase activity [GO:0008081]	glycerophosphodiester phosphodiesterase activity [GO:0008889]; metal ion binding [GO:0046872]
d1zclb__d4jmka___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cell cycle [GO:0007049]; multicellular organism development [GO:0007275]; positive regulation of cell migration [GO:0030335]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]	cell cycle [GO:0007049]; multicellular organism development [GO:0007275]; positive regulation of cell migration [GO:0030335]	dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]	cytoplasm [GO:0005737]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1zcpb__d2fy6a1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; cell redox homeostasis [GO:0045454]; cellular protein modification process [GO:0006464]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; cellular protein modification process [GO:0006464]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]
d1zcpb__d3dyrb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1zcpc__d4mabb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	thioredoxin peroxidase activity [GO:0008379]
d1zcpd__d1pl1b2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d1zcrb__d5fw7b___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d1zcsa6_d1n61d1__1				Proteobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1zcsa7_d1n60b1__1				Proteobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d1zcsa7_d3sr6l1__1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1zcza1_d2b1ga1__1		Metazoa	Thermotogae	Chordata	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]	cytosol [GO:0005829]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d1zczb1_d1ik4a___1			Thermotogae	Proteobacteria	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' IMP biosynthetic process [GO:0006189]	methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]	cytosol [GO:0005829]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]	methylglyoxal synthase activity [GO:0008929]
d1zd3a2_d1to7b2__1	Metazoa		Chordata		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	
d1zd5a2_d5llsa2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d1zd9a1_d4edha___1	Metazoa		Chordata	Proteobacteria	axon cytoplasm [GO:1904115]; azurophil granule membrane [GO:0035577]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; midbody [GO:0030496]; plasma membrane [GO:0005886]; spindle midzone [GO:0051233]; synapse [GO:0045202]; vacuolar membrane [GO:0005774]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; anterograde axonal transport [GO:0008089]; cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; neutrophil degranulation [GO:0043312]; protein transport [GO:0015031]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	anterograde axonal transport [GO:0008089]; cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; neutrophil degranulation [GO:0043312]; protein transport [GO:0015031]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	axon cytoplasm [GO:1904115]; azurophil granule membrane [GO:0035577]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; midbody [GO:0030496]; plasma membrane [GO:0005886]; spindle midzone [GO:0051233]; synapse [GO:0045202]; vacuolar membrane [GO:0005774]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]
d1zdhc__d2quxp___1					T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	viral capsid [GO:0019028]	regulation of translation [GO:0006417]		T=3 icosahedral viral capsid [GO:0039617]	viral capsid [GO:0019028]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	
d1zdib__d1fr5c___1					T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d1zdnb__d2c4od___1	Metazoa		Chordata		anaphase-promoting complex [GO:0005680]; cell [GO:0005623]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; exit from mitosis [GO:0010458]; free ubiquitin chain polymerization [GO:0010994]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K6-linked ubiquitination [GO:0085020]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]		anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; exit from mitosis [GO:0010458]; free ubiquitin chain polymerization [GO:0010994]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]		anaphase-promoting complex [GO:0005680]; cell [GO:0005623]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]		anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]	
d1zdqa1_d3plyd___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1zdqa2_d5n0ka2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	anchored component of plasma membrane [GO:0046658]; cell [GO:0005623]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; aging [GO:0007568]; cellular iron ion homeostasis [GO:0006879]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; liver development [GO:0001889]; lung development [GO:0030324]; plasma membrane copper ion transport [GO:0015679]; response to copper ion [GO:0046688]; response to nutrient [GO:0007584]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	aging [GO:0007568]; cellular iron ion homeostasis [GO:0006879]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; liver development [GO:0001889]; lung development [GO:0030324]; plasma membrane copper ion transport [GO:0015679]; response to copper ion [GO:0046688]; response to nutrient [GO:0007584]	periplasmic space [GO:0042597]	anchored component of plasma membrane [GO:0046658]; cell [GO:0005623]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d1zdqb2_d2bz7a___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1zdqc1_d3t6vb2__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1zdqc2_d1aspa3__1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	extracellular region [GO:0005576]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]
d1zdra__d1ra1a___1			Firmicutes	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d1zdrb__d1qzfa1__1			Firmicutes	Apicomplexa	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]
d1zdsb1_d1ic0b___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	metal ion binding [GO:0046872]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	metal ion binding [GO:0046872]
d1zdsb2_d3ef4a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d1zdza__d3anxb___1				Deinococcus-Thermus		cytoplasm [GO:0005737]; agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; spermine synthase activity [GO:0016768]; thermospermine synthase activity [GO:0010487]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]		polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]		cytoplasm [GO:0005737]		agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; spermine synthase activity [GO:0016768]; thermospermine synthase activity [GO:0010487]
d1zdzb__d2e5wc___1				Euryarchaeota		cytoplasm [GO:0005737]; spermidine synthase activity [GO:0004766]; spermidine biosynthetic process [GO:0008295]		spermidine biosynthetic process [GO:0008295]		cytoplasm [GO:0005737]		spermidine synthase activity [GO:0004766]
d1ze1a2_d2ey4b2__1			Thermotogae	Euryarchaeota	mitochondrion [GO:0005739]; pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]; mRNA pseudouridine synthesis [GO:1990481]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	snoRNA binding [GO:0030515]; pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	mRNA pseudouridine synthesis [GO:1990481]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	mitochondrion [GO:0005739]		pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]	snoRNA binding [GO:0030515]
d1zema1_d5jydg___1			Proteobacteria	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]					nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d1zemc__d1adfa2__1		Metazoa	Proteobacteria	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d1zemh__d1g1ad___1			Proteobacteria	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; NADH binding [GO:0070404]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]			nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; NADH binding [GO:0070404]
d1zepa1_d1zvra2__1		Metazoa		Chordata		axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]; identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]		dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]		axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]		identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d1zeta1_d3bq1a1__1	Metazoa		Chordata	Crenarchaeota	cytoplasmic ribonucleoprotein granule [GO:0036464]; intracellular [GO:0005622]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	cytoplasmic ribonucleoprotein granule [GO:0036464]; intracellular [GO:0005622]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d1zfpe__d4ohea1__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]; abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]
d1zg3a2_d1p1bd___1	Viridiplantae	Metazoa	Streptophyta	Chordata	2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity [GO:0102670]; isoflavone 4'-O-methyltransferase activity [GO:0030746]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]		creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity [GO:0102670]; isoflavone 4'-O-methyltransferase activity [GO:0030746]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]	guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d1zg7a__d4uiba1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d1zg8b__d2odff___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]		extracellular space [GO:0005615]		metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	
d1zgaa2_d3b7pa___1	Viridiplantae		Streptophyta	Apicomplexa	2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity [GO:0102670]; isoflavone 4'-O-methyltransferase activity [GO:0030746]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]		polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]		cytosol [GO:0005829]	2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity [GO:0102670]; isoflavone 4'-O-methyltransferase activity [GO:0030746]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]	spermidine synthase activity [GO:0004766]
d1zgfa__d5ll5a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; chloride ion homeostasis [GO:0055064]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; chloride ion homeostasis [GO:0055064]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d1zgld1_d6azze1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1zgle2_d1uvqa2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; interferon-gamma-mediated signaling pathway [GO:0060333]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; interferon-gamma-mediated signaling pathway [GO:0060333]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d1zglg1_d1j88d1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	Fc-epsilon receptor signaling pathway [GO:0038095]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	IgE binding [GO:0019863]
d1zglh2_d5ujtd1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1zglj1_d1de4b___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1zglj1_d4hiha2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1zglk2_d1ieab2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1zglr1_d1d5ba1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1zglr1_d4xnul1__1	Metazoa	Metazoa	Chordata	Arthropoda	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]; adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of plasma membrane [GO:0005887]; neuronal cell body membrane [GO:0032809]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]
d1zglr2_d4kjyd___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; thrombospondin receptor activity [GO:0070053]; cell migration [GO:0016477]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; neutrophil degranulation [GO:0043312]; opsonization [GO:0008228]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of inflammatory response [GO:0050729]; positive regulation of phagocytosis [GO:0050766]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell activation [GO:0050870]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-10 production [GO:0032653]; regulation of interleukin-12 production [GO:0032655]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell migration [GO:0016477]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; neutrophil degranulation [GO:0043312]; opsonization [GO:0008228]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of inflammatory response [GO:0050729]; positive regulation of phagocytosis [GO:0050766]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell activation [GO:0050870]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-10 production [GO:0032653]; regulation of interleukin-12 production [GO:0032655]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; thrombospondin receptor activity [GO:0070053]
d1zglr2_d4rgng2__1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1zglt1_d1ub5b2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1zglv2_d1i8ma2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1zglv2_d5nuzl1__1	Metazoa		Chordata	Negarnaviricota	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi membrane [GO:0044178]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; metal ion binding [GO:0046872]; fusion of virus membrane with host endosome membrane [GO:0039654]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	fusion of virus membrane with host endosome membrane [GO:0039654]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi membrane [GO:0044178]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d1zgta2_d1zira1__1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d1zh2a1_d3ltej___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding [GO:0003677]
d1zh2a1_d6chya___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d1zh2b__d5e3jb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding [GO:0003677]
d1zh4a__d3fgzb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d1zh4a__d5iunf___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of transcription, DNA-templated [GO:0006355]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]; protein dimerization activity [GO:0046983]	regulation of transcription, DNA-templated [GO:0006355]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]; protein dimerization activity [GO:0046983]
d1zhbd1_d43c9b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1zhbe__d1uxsa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1zhbg1_d5nlua1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1zhbh__d1u8qa1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1zhbj1_d2qr0x1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1zhbk__d3hb3c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1zhfa2_d2br5b___1	Viridiplantae		Streptophyta	Actinobacteria	2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity [GO:0102670]; isoflavone 4'-O-methyltransferase activity [GO:0030746]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]		lipid biosynthetic process [GO:0008610]			2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity [GO:0102670]; isoflavone 4'-O-methyltransferase activity [GO:0030746]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]	methyltransferase activity [GO:0008168]
d1zhha__d1gudb___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]; signal transduction by protein phosphorylation [GO:0023014]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; monosaccharide binding [GO:0048029]; carbohydrate transport [GO:0008643]	signal transduction by protein phosphorylation [GO:0023014]	carbohydrate transport [GO:0008643]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	ATP binding [GO:0005524]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]	monosaccharide binding [GO:0048029]
d1zhha__d4n0qa___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]; signal transduction by protein phosphorylation [GO:0023014]	amino acid transport [GO:0006865]	signal transduction by protein phosphorylation [GO:0023014]	amino acid transport [GO:0006865]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]	
d1zhka1_d5t5nl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]; chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d1zhla2_d4aena1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1zhlb__d3d85a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1zhlb__d4odub2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1zhnb__d3upcg___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1zhpa__d1mtsa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1zi6a__d5tnid___1			Proteobacteria	Proteobacteria	carboxymethylenebutenolidase activity [GO:0008806]; aromatic compound catabolic process [GO:0019439]	hydrolase activity [GO:0016787]	aromatic compound catabolic process [GO:0019439]				carboxymethylenebutenolidase activity [GO:0008806]	hydrolase activity [GO:0016787]
d1zi7b__d1zhxa2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; lipid binding [GO:0008289]; oxysterol binding [GO:0008142]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; sterol binding [GO:0032934]; sterol transfer activity [GO:0120015]; sterol transporter activity [GO:0015248]; endocytosis [GO:0006897]; ER to Golgi ceramide transport [GO:0035621]; exocytosis [GO:0006887]; maintenance of cell polarity [GO:0030011]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of phosphatase activity [GO:0010922]; post-Golgi vesicle-mediated transport [GO:0006892]; sphingolipid metabolic process [GO:0006665]; sterol biosynthetic process [GO:0016126]; sterol transport [GO:0015918]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; lipid binding [GO:0008289]; oxysterol binding [GO:0008142]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; sterol binding [GO:0032934]; sterol transfer activity [GO:0120015]; sterol transporter activity [GO:0015248]; endocytosis [GO:0006897]; ER to Golgi ceramide transport [GO:0035621]; exocytosis [GO:0006887]; maintenance of cell polarity [GO:0030011]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of phosphatase activity [GO:0010922]; post-Golgi vesicle-mediated transport [GO:0006892]; sphingolipid metabolic process [GO:0006665]; sterol biosynthetic process [GO:0016126]; sterol transport [GO:0015918]	endocytosis [GO:0006897]; ER to Golgi ceramide transport [GO:0035621]; exocytosis [GO:0006887]; maintenance of cell polarity [GO:0030011]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of phosphatase activity [GO:0010922]; post-Golgi vesicle-mediated transport [GO:0006892]; sphingolipid metabolic process [GO:0006665]; sterol biosynthetic process [GO:0016126]; sterol transport [GO:0015918]	endocytosis [GO:0006897]; ER to Golgi ceramide transport [GO:0035621]; exocytosis [GO:0006887]; maintenance of cell polarity [GO:0030011]; piecemeal microautophagy of the nucleus [GO:0034727]; positive regulation of phosphatase activity [GO:0010922]; post-Golgi vesicle-mediated transport [GO:0006892]; sphingolipid metabolic process [GO:0006665]; sterol biosynthetic process [GO:0016126]; sterol transport [GO:0015918]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]	lipid binding [GO:0008289]; oxysterol binding [GO:0008142]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; sterol binding [GO:0032934]; sterol transfer activity [GO:0120015]; sterol transporter activity [GO:0015248]	lipid binding [GO:0008289]; oxysterol binding [GO:0008142]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; sterol binding [GO:0032934]; sterol transfer activity [GO:0120015]; sterol transporter activity [GO:0015248]
d1zi8a__d1zica___1			Proteobacteria	Proteobacteria	carboxymethylenebutenolidase activity [GO:0008806]; aromatic compound catabolic process [GO:0019439]	carboxymethylenebutenolidase activity [GO:0008806]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			carboxymethylenebutenolidase activity [GO:0008806]	carboxymethylenebutenolidase activity [GO:0008806]
d1ziaa__d3t6vb1__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]			periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d1ziea1_d3so1d___1	Metazoa		Chordata	Firmicutes	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1ziea2_d3hz2a___1	Metazoa		Chordata	Euryarchaeota	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1ziqa2_d2jdfa2__1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; lens fiber cell morphogenesis [GO:0070309]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; lens fiber cell morphogenesis [GO:0070309]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d1zira2_d3i9hc___1	Metazoa		Chordata	Firmicutes	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1zj8a2_d3mmcd2__1			Actinobacteria	Euryarchaeota	cell wall [GO:0005618]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]	sulfur compound metabolic process [GO:0006790]	cell wall [GO:0005618]; cytosol [GO:0005829]	membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d1zj8a4_d3vksa2__1		Viridiplantae	Actinobacteria	Streptophyta	cell wall [GO:0005618]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]		cell wall [GO:0005618]; cytosol [GO:0005829]		4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1zj8b2_d3geoa2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]	sulfite reductase complex (NADPH) [GO:0009337]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	cell wall [GO:0005618]; cytosol [GO:0005829]	sulfite reductase complex (NADPH) [GO:0009337]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]
d1zj8b3_d3vlza4__1		Viridiplantae	Actinobacteria	Streptophyta	cell wall [GO:0005618]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]		cell wall [GO:0005618]; cytosol [GO:0005829]		4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1zj8b4_d3vm0a2__1		Viridiplantae	Actinobacteria	Streptophyta	cell wall [GO:0005618]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]		cell wall [GO:0005618]; cytosol [GO:0005829]		4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d1zjaa1_d3w38a2__1		Viridiplantae	Proteobacteria	Streptophyta	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]	carbohydrate metabolic process [GO:0005975]				isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]
d1zjaa2_d1gvia2__1			Proteobacteria	Deinococcus-Thermus	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]
d1zjab2_d2fh8a4__1			Proteobacteria	Proteobacteria	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		plasma membrane [GO:0005886]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]
d1zjbb1_d1xcwa2__1		Metazoa	Proteobacteria	Chordata	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d1zjbb2_d4nxsa2__1		Metazoa	Proteobacteria	Chordata	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d1zjda1_d1lpgb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1zjna1_d4qzga1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1zjwa2_d4r0ne___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d1zjya1_d5l7ya1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]		estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]
d1zk0a__d3aogf2__1			Firmicutes	Deinococcus-Thermus	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]			metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d1zk2a__d1qsgd___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]		biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]; membrane [GO:0016020]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]
d1zk3g__d1j4ab1__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]					metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	D-lactate dehydrogenase activity [GO:0008720]; NAD binding [GO:0051287]
d1zkcb2_d2ck1a___1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; Golgi lumen [GO:0005796]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-ubiquitin ligase activity [GO:0034450]; leukocyte migration [GO:0050900]; protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; protein peptidyl-prolyl isomerization [GO:0000413]; protein polyubiquitination [GO:0000209]	cytoplasm [GO:0005737]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; protein folding [GO:0006457]	leukocyte migration [GO:0050900]; protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; protein peptidyl-prolyl isomerization [GO:0000413]; protein polyubiquitination [GO:0000209]	protein folding [GO:0006457]	cytoplasm [GO:0005737]; Golgi lumen [GO:0005796]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-ubiquitin ligase activity [GO:0034450]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]
d1zkfa__d1cyna___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; unfolded protein binding [GO:0051082]; bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by host of viral process [GO:0044794]; positive regulation of multicellular organism growth [GO:0040018]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by host of viral process [GO:0044794]; positive regulation of multicellular organism growth [GO:0040018]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; unfolded protein binding [GO:0051082]
d1zkfb__d4i9ya1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	annulate lamellae [GO:0005642]; cytoplasm [GO:0005737]; cytoplasmic periphery of the nuclear pore complex [GO:1990723]; cytosol [GO:0005829]; host cell [GO:0043657]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear inclusion body [GO:0042405]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear pore cytoplasmic filaments [GO:0044614]; nuclear pore nuclear basket [GO:0044615]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; centrosome localization [GO:0051642]; intracellular transport of virus [GO:0075733]; mRNA export from nucleus [GO:0006406]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of GTPase activity [GO:0043547]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of gene silencing by miRNA [GO:0060964]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110]; response to amphetamine [GO:0001975]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	centrosome localization [GO:0051642]; intracellular transport of virus [GO:0075733]; mRNA export from nucleus [GO:0006406]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of glucokinase activity [GO:0033133]; positive regulation of GTPase activity [GO:0043547]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of gene silencing by miRNA [GO:0060964]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110]; response to amphetamine [GO:0001975]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	annulate lamellae [GO:0005642]; cytoplasm [GO:0005737]; cytoplasmic periphery of the nuclear pore complex [GO:1990723]; cytosol [GO:0005829]; host cell [GO:0043657]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear inclusion body [GO:0042405]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear pore cytoplasmic filaments [GO:0044614]; nuclear pore nuclear basket [GO:0044615]; nucleus [GO:0005634]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]
d1zkha1_d3jsva___1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type prespliceosome [GO:0071004]; U2-type spliceosomal complex [GO:0005684]; RNA binding [GO:0003723]; mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type prespliceosome [GO:0071004]; U2-type spliceosomal complex [GO:0005684]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	RNA binding [GO:0003723]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d1zkna__d4msnb1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d1zknb__d5tzza1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d1zknc__d3hr1a___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]
d1zknd__d5vp0a___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d1zkra1_d1utga___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]	extracellular region [GO:0005576]; phospholipase A2 inhibitor activity [GO:0019834]; steroid binding [GO:0005496]; signal transduction [GO:0007165]		signal transduction [GO:0007165]	extracellular space [GO:0005615]	extracellular region [GO:0005576]		phospholipase A2 inhibitor activity [GO:0019834]; steroid binding [GO:0005496]
d1zkrb1_d1zkrb2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]	extracellular space [GO:0005615]			extracellular space [GO:0005615]	extracellular space [GO:0005615]		
d1zkwb__d5uuda___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d1zl0b2_d4enpb2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; carboxypeptidase activity [GO:0004180]; serine-type peptidase activity [GO:0008236]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carboxypeptidase activity [GO:0004180]; serine-type peptidase activity [GO:0008236]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1zl3a2_d2nr0b1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]; mRNA pseudouridine synthesis [GO:1990481]; pseudouridine synthesis [GO:0001522]; RNA folding [GO:0034337]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]; tRNA pseudouridine synthesis [GO:0031119]	mRNA pseudouridine synthesis [GO:1990481]; pseudouridine synthesis [GO:0001522]; RNA folding [GO:0034337]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	tRNA pseudouridine synthesis [GO:0031119]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]	pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]
d1zl7a__d4ntyc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]; regulation of blood pressure [GO:0008217]	integral component of plasma membrane [GO:0005887]; acid-sensing ion channel activity [GO:0044736]; identical protein binding [GO:0042802]; cellular response to pH [GO:0071467]; protein homotrimerization [GO:0070207]; sodium ion transmembrane transport [GO:0035725]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]; regulation of blood pressure [GO:0008217]	cellular response to pH [GO:0071467]; protein homotrimerization [GO:0070207]; sodium ion transmembrane transport [GO:0035725]	extracellular region [GO:0005576]	integral component of plasma membrane [GO:0005887]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	acid-sensing ion channel activity [GO:0044736]; identical protein binding [GO:0042802]
d1zl9a2_d1mtcb1__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; innate immune response [GO:0045087]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	glutathione metabolic process [GO:0006749]; innate immune response [GO:0045087]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]		cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	glutathione transferase activity [GO:0004364]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d1zl9b2_d4f0bb2__1	Metazoa	Fungi	Nematoda (roundworms)	Basidiomycota	glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; innate immune response [GO:0045087]	transferase activity [GO:0016740]	glutathione metabolic process [GO:0006749]; innate immune response [GO:0045087]				glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d1zlae__d3aywg___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1zlpa__d1igwc___1	Viridiplantae		Streptophyta	Proteobacteria	citramalate lyase activity [GO:0047776]; metal ion binding [GO:0046872]; oxaloacetase activity [GO:0030603]; transferase activity [GO:0016740]	cytosol [GO:0005829]; cation binding [GO:0043169]; isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]		glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]	citramalate lyase activity [GO:0047776]; metal ion binding [GO:0046872]; oxaloacetase activity [GO:0030603]; transferase activity [GO:0016740]	cation binding [GO:0043169]; isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]
d1zlra__d1uk2b___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1zlsh1_d1l0xa1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]		
d1zluk1_d2imma___1												
d1zluk2_d4pjge1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1zlum1_d2bnqe1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]		
d1zlvk2_d1u3hf___1		Metazoa		Chordata		T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]		T cell receptor complex [GO:0042101]		
d1zlvl2_d4ygad___1				Apicomplexa		ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; protein kinase activity [GO:0004672]						ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; protein kinase activity [GO:0004672]
d1zlvm1_d1beyl2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1zlwh1_d4kk6f2__1				Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d1zlwh2_d3b5hb2__1		Metazoa		Chordata		acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]		axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]		acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]		cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]
d1zlwk1_d5d93e1__1		Metazoa		Chordata		cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; FAD binding [GO:0071949]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]; extracellular matrix assembly [GO:0085029]; negative regulation of macroautophagy [GO:0016242]		cell redox homeostasis [GO:0045454]; extracellular matrix assembly [GO:0085029]; negative regulation of macroautophagy [GO:0016242]		cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]		FAD binding [GO:0071949]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide isomerase activity [GO:0003756]
d1zlwk2_d1kiqb1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1zlya__d4qpca1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydrolase activity [GO:0016787]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; embryonic viscerocranium morphogenesis [GO:0048703]; gastrulation [GO:0007369]; heart development [GO:0007507]; neural crest cell migration [GO:0001755]; neuromast deposition [GO:0048885]; one-carbon metabolic process [GO:0006730]	'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; embryonic viscerocranium morphogenesis [GO:0048703]; gastrulation [GO:0007369]; heart development [GO:0007507]; neural crest cell migration [GO:0001755]; neuromast deposition [GO:0048885]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydrolase activity [GO:0016787]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]
d1zlza1_d4gunc1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1zlza2_d4l2ca2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1zlzb2_d3lioa2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1zm2a1_d4m0ld2__1			Proteobacteria	Crenarchaeota	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1zm2d__d4xhua2__1		Metazoa	Proteobacteria	Chordata	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]		apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]		membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d1zm2e4_d3b8ha5__1			Proteobacteria	Proteobacteria	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]					NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d1zm2f__d3c4ha2__1		Metazoa	Proteobacteria	Chordata	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; catalytic activity [GO:0003824]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]		DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]		centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	catalytic activity [GO:0003824]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]
d1zm3a1_d2pmdb1__1			Proteobacteria	Crenarchaeota	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1zm3a5_d1zm2a4__1			Proteobacteria	Proteobacteria	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]					NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d1zm3c1_d1efta1__1			Proteobacteria	Deinococcus-Thermus	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1zm3c5_d1fnma4__1			Proteobacteria	Deinococcus-Thermus	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]		translational elongation [GO:0006414]		cytoplasm [GO:0005737]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]
d1zm3f__d4pjva2__1		Metazoa	Proteobacteria	Chordata	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; base-excision repair [GO:0006284]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of neuron death [GO:1901215]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; protein ADP-ribosylation [GO:0006471]; protein poly-ADP-ribosylation [GO:0070212]		base-excision repair [GO:0006284]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of neuron death [GO:1901215]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; protein ADP-ribosylation [GO:0006471]; protein poly-ADP-ribosylation [GO:0070212]		nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	DNA binding [GO:0003677]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]
d1zm4a1_d1d2eb1__1		Metazoa	Proteobacteria	Chordata	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]		mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1zm4c1_d2crva1__1		Metazoa	Proteobacteria	Chordata	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosomal small subunit binding [GO:0043024]; translation factor activity, RNA binding [GO:0008135]; translation initiation factor activity [GO:0003743]; mitochondrial translational initiation [GO:0070124]; ribosome disassembly [GO:0032790]		mitochondrial translational initiation [GO:0070124]; ribosome disassembly [GO:0032790]		mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosomal small subunit binding [GO:0043024]; translation factor activity, RNA binding [GO:0008135]; translation initiation factor activity [GO:0003743]
d1zm4c1_d4m0lc2__1			Proteobacteria	Crenarchaeota	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d1zm4e1_d3p3md2__1			Proteobacteria		NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]						NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	
d1zm7b__d4c9ba1__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; U2-type catalytic step 1 spliceosome [GO:0071006]; ATP binding [GO:0005524]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA stem-loop binding [GO:0035613]; selenocysteine insertion sequence binding [GO:0035368]; translation regulator activity [GO:0045182]; associative learning [GO:0008306]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to selenite ion [GO:0072715]; embryonic cranial skeleton morphogenesis [GO:0048701]; exploration behavior [GO:0035640]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of selenocysteine incorporation [GO:1904570]; negative regulation of selenocysteine insertion sequence binding [GO:1904574]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; response to organic cyclic compound [GO:0014070]; RNA export from nucleus [GO:0006405]; rRNA processing [GO:0006364]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	associative learning [GO:0008306]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to selenite ion [GO:0072715]; embryonic cranial skeleton morphogenesis [GO:0048701]; exploration behavior [GO:0035640]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of selenocysteine incorporation [GO:1904570]; negative regulation of selenocysteine insertion sequence binding [GO:1904574]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; response to organic cyclic compound [GO:0014070]; RNA export from nucleus [GO:0006405]; rRNA processing [GO:0006364]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; U2-type catalytic step 1 spliceosome [GO:0071006]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]	ATP binding [GO:0005524]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA stem-loop binding [GO:0035613]; selenocysteine insertion sequence binding [GO:0035368]; translation regulator activity [GO:0045182]
d1zm7d__d1vhlb1__1	Metazoa		Arthropoda	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; dephospho-CoA kinase activity [GO:0004140]; coenzyme A biosynthetic process [GO:0015937]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]	ATP binding [GO:0005524]; dephospho-CoA kinase activity [GO:0004140]
d1zm9a1_d1aipe1__1			Proteobacteria	Deinococcus-Thermus	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1zm9e1_d3bbxd1__1			Proteobacteria	Proteobacteria	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]
d1zm9e5_d2bm0a5__1			Proteobacteria	Deinococcus-Thermus	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]		translational elongation [GO:0006414]		cytoplasm [GO:0005737]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]
d1zmga__d1aiva2__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]
d1zmla__d1inca___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1zmoa__d4aj4a1__1		Metazoa	Actinobacteria	Chordata		cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1zmoc__d5ijzh2__1			Actinobacteria	Actinobacteria		cytoplasm [GO:0005737]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; glutamate biosynthetic process [GO:0006537]		glutamate biosynthetic process [GO:0006537]		cytoplasm [GO:0005737]		glutamate dehydrogenase (NADP+) activity [GO:0004354]
d1zmod__d3rj9e___1		Metazoa	Actinobacteria	Arthropoda		alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]; alcohol metabolic process [GO:0006066]		alcohol metabolic process [GO:0006066]				alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]
d1zmog__d4qsmf1__1		Metazoa	Actinobacteria	Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]		cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d1zmra__d2cunb___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; positive regulation of oxidative phosphorylation [GO:1903862]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; positive regulation of oxidative phosphorylation [GO:1903862]	glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]	ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]
d1zmta__d3a28b___1			Proteobacteria	Actinobacteria		(S,S)-butanediol dehydrogenase activity [GO:0047512]; diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]; acetoin catabolic process [GO:0045150]; acetoin metabolic process [GO:0045149]; butanediol metabolic process [GO:0034077]; protein homotetramerization [GO:0051289]		acetoin catabolic process [GO:0045150]; acetoin metabolic process [GO:0045149]; butanediol metabolic process [GO:0034077]; protein homotetramerization [GO:0051289]				(S,S)-butanediol dehydrogenase activity [GO:0047512]; diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]
d1zmya1_d4nkil2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1zmym__d4cgef___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	hydrolase activity [GO:0016787]
d1zn1a1_d1ge9a___1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]	cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]	cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ribosomal large subunit binding [GO:0043023]	ribosomal large subunit binding [GO:0043023]
d1zn1a1_d4kb2a___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]	cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]	cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]; translational termination [GO:0006415]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	ribosomal large subunit binding [GO:0043023]	ribosomal large subunit binding [GO:0043023]; translation termination factor activity [GO:0008079]
d1zn2a1_d1a04a1__1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; nitrate assimilation [GO:0042128]; phosphorelay signal transduction system [GO:0000160]; regulation of gene expression [GO:0010468]; regulation of nitrate assimilation [GO:0090352]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	nitrate assimilation [GO:0042128]; phosphorelay signal transduction system [GO:0000160]; regulation of gene expression [GO:0010468]; regulation of nitrate assimilation [GO:0090352]; regulation of transcription, DNA-templated [GO:0006355]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1zn2a2_d1ys7a2__1			Proteobacteria	Actinobacteria	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; calcium ion binding [GO:0005509]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; magnesium ion binding [GO:0000287]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; growth involved in symbiotic interaction [GO:0044110]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	growth involved in symbiotic interaction [GO:0044110]		cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; magnesium ion binding [GO:0000287]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1zn9b__d2wnsa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]; adenine binding [GO:0002055]; adenine phosphoribosyltransferase activity [GO:0003999]; AMP binding [GO:0016208]; adenine salvage [GO:0006168]; AMP salvage [GO:0044209]; cellular response to insulin stimulus [GO:0032869]; grooming behavior [GO:0007625]; lactation [GO:0007595]; neutrophil degranulation [GO:0043312]; purine ribonucleoside salvage [GO:0006166]; purine-containing compound salvage [GO:0043101]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; identical protein binding [GO:0042802]; orotate phosphoribosyltransferase activity [GO:0004588]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular response to drug [GO:0035690]; female pregnancy [GO:0007565]; lactation [GO:0007595]; pyrimidine nucleobase biosynthetic process [GO:0019856]; pyrimidine nucleoside biosynthetic process [GO:0046134]; UMP biosynthetic process [GO:0006222]	adenine salvage [GO:0006168]; AMP salvage [GO:0044209]; cellular response to insulin stimulus [GO:0032869]; grooming behavior [GO:0007625]; lactation [GO:0007595]; neutrophil degranulation [GO:0043312]; purine-containing compound salvage [GO:0043101]; purine ribonucleoside salvage [GO:0006166]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular response to drug [GO:0035690]; female pregnancy [GO:0007565]; lactation [GO:0007595]; pyrimidine nucleobase biosynthetic process [GO:0019856]; pyrimidine nucleoside biosynthetic process [GO:0046134]; UMP biosynthetic process [GO:0006222]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	adenine binding [GO:0002055]; adenine phosphoribosyltransferase activity [GO:0003999]; AMP binding [GO:0016208]	identical protein binding [GO:0042802]; orotate phosphoribosyltransferase activity [GO:0004588]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d1znda__d4np1a___1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	vasodilation [GO:0042311]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]
d1znga__d5ce4a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]
d1znka__d1bwya___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	mitochondrial matrix [GO:0005759]; lipid binding [GO:0008289]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]		cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	mitochondrial matrix [GO:0005759]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	lipid binding [GO:0008289]
d1znka__d1x8uc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d1znqo2_d1gadp2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]	cytosol [GO:0005829]; membrane [GO:0016020]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	cytosol [GO:0005829]; membrane [GO:0016020]	aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1znqq2_d2cvoa2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]	chloroplast [GO:0009507]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	chloroplast [GO:0009507]	aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]	N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]
d1znvc__d4qkoa___1			Proteobacteria	Proteobacteria	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	bacteriocin immunity [GO:0030153]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]			toxic substance binding [GO:0015643]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]
d1znwa__d1tf7f1__1			Actinobacteria	Cyanobacteria	cytosol [GO:0005829]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; guanylate kinase activity [GO:0004385]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]		circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]		adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; guanylate kinase activity [GO:0004385]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]
d1znwa__d2zzzc___1			Actinobacteria		cytosol [GO:0005829]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; guanylate kinase activity [GO:0004385]; magnesium ion binding [GO:0000287]				cytosol [GO:0005829]		adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; guanylate kinase activity [GO:0004385]; magnesium ion binding [GO:0000287]	
d1znya__d1d8ta3__1			Actinobacteria	Actinobacteria	cytosol [GO:0005829]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; guanylate kinase activity [GO:0004385]; magnesium ion binding [GO:0000287]	extracellular region [GO:0005576]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]		cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytosol [GO:0005829]	extracellular region [GO:0005576]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; guanylate kinase activity [GO:0004385]; magnesium ion binding [GO:0000287]	
d1znza__d1tuia3__1			Actinobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; guanylate kinase activity [GO:0004385]; magnesium ion binding [GO:0000287]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]			cytosol [GO:0005829]	cytoplasm [GO:0005737]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; guanylate kinase activity [GO:0004385]; magnesium ion binding [GO:0000287]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d1zo2b__d1u5oa___1		Metazoa	Apicomplexa	Chordata		cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]		mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]		cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]		identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]
d1zo4a__d1f4ta___1			Firmicutes	Crenarchaeota	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]
d1zo4b__d4egmc___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]			cytoplasm [GO:0005737]		aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1zo8b__d5bshe1__1		Viridiplantae	Proteobacteria	Streptophyta		cell wall [GO:0005618]; nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]; L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]		L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]		cell wall [GO:0005618]		nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d1zo8e__d2irwh___1		Metazoa	Proteobacteria	Chordata		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d1zo8j__d2frmd3__1			Proteobacteria									
d1zo8o__d1pqwa___1			Proteobacteria	Actinobacteria		cytosol [GO:0005829]; plasma membrane [GO:0005886]; polyketide synthase complex [GO:0034081]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; oxidoreductase activity [GO:0016491]; phosphopantetheine binding [GO:0031177]; Actinobacterium-type cell wall biogenesis [GO:0071766]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; phenolic phthiocerol biosynthetic process [GO:0097041]; phthiocerol biosynthetic process [GO:0097040]		Actinobacterium-type cell wall biogenesis [GO:0071766]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; phenolic phthiocerol biosynthetic process [GO:0097041]; phthiocerol biosynthetic process [GO:0097040]		cytosol [GO:0005829]; plasma membrane [GO:0005886]; polyketide synthase complex [GO:0034081]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; oxidoreductase activity [GO:0016491]; phosphopantetheine binding [GO:0031177]
d1zo8p__d1dird___1		Metazoa	Proteobacteria	Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; 6,7-dihydropteridine reductase activity [GO:0004155]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; cellular response to drug [GO:0035690]; L-phenylalanine catabolic process [GO:0006559]; liver development [GO:0001889]; response to aluminum ion [GO:0010044]; response to glucagon [GO:0033762]; response to lead ion [GO:0010288]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cellular response to drug [GO:0035690]; liver development [GO:0001889]; L-phenylalanine catabolic process [GO:0006559]; response to aluminum ion [GO:0010044]; response to glucagon [GO:0033762]; response to lead ion [GO:0010288]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]		6,7-dihydropteridine reductase activity [GO:0004155]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]
d1zo9a__d3lxia___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]			cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1zoaa__d4g3jc___1			Firmicutes		cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d1zoab__d5y5lb___1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]			cytoplasm [GO:0005737]		aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d1zofa1_d1uulc___1			Proteobacteria		cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]; cytoplasm [GO:0005737]		peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	
d1zofg__d1qk8a___1			Proteobacteria		cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	
d1zofh__d2xpdc1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	thioredoxin peroxidase activity [GO:0008379]
d1zofi__d1o7ua___1			Proteobacteria		cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	
d1zoia__d4dgqc1__1			Proteobacteria	Proteobacteria		chloride peroxidase activity [GO:0016691]						chloride peroxidase activity [GO:0016691]
d1zoia__d4hs9a___1			Proteobacteria	Proteobacteria		metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]						metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d1zoib__d1dqza___1			Proteobacteria	Actinobacteria		cell wall [GO:0005618]; extracellular region [GO:0005576]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]		glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; extracellular region [GO:0005576]		diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]
d1zoic__d3head___1			Proteobacteria	Proteobacteria		arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]						arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]
d1zopb__d1idn2___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]
d1zopb__d3ppwa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d1zora__d2ztwa___1			Thermotogae	Deinococcus-Thermus	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]		cytoplasm [GO:0005737]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]	3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d1zosd__d3onvb___1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]
d1zose__d3phca___1			Firmicutes	Apicomplexa	cytosol [GO:0005829]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]	nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]		adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]	purine-nucleoside phosphorylase activity [GO:0004731]
d1zowa1_d1ulqa2__1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d1zowc2_d2buid1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d1zowc2_d3kzuc2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d1zp5a__d1iaba___1	Metazoa	Metazoa	Chordata	Arthropoda	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cortical granule [GO:0060473]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; aspartic-type peptidase activity [GO:0070001]; glutamic-type peptidase activity [GO:0070002]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]; cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cortical granule [GO:0060473]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	aspartic-type peptidase activity [GO:0070001]; glutamic-type peptidase activity [GO:0070002]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]
d1zpca__d2j34a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d1zpda1_d1ypda2__1			Proteobacteria		magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]						magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	
d1zpdb1_d4juaa2__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1zpde1_d2ji8b1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]		oxalate catabolic process [GO:0033611]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d1zpde1_d2wvhv2__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d1zpde2_d4feea3__1			Proteobacteria		magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]						magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	
d1zpdf2_d1t9ca2__1		Fungi	Proteobacteria	Ascomycota	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1zpdf3_d4k9od3__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d1zpwx1_d4qr1a___1			Deinococcus-Thermus	Firmicutes	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; defense response to virus [GO:0051607]; maintenance of CRISPR repeat elements [GO:0043571]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; defense response to virus [GO:0051607]; maintenance of CRISPR repeat elements [GO:0043571]	defense response to virus [GO:0051607]; maintenance of CRISPR repeat elements [GO:0043571]	defense response to virus [GO:0051607]; maintenance of CRISPR repeat elements [GO:0043571]			endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]
d1zq0a__d1gytk1__1				Proteobacteria		cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]		peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]		cytoplasm [GO:0005737]		aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]
d1zq0a__d5cb5p___1				Proteobacteria		endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]; negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]		negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]				endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]
d1zq1d2_d2d6fd2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]; translation [GO:0006412]	cytoplasm [GO:0005737]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]
d1zq9a1_d5fula___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity [GO:0052909]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]; positive regulation of rRNA processing [GO:2000234]; rRNA methylation [GO:0031167]	methyltransferase activity [GO:0008168]; protein methylation [GO:0006479]	positive regulation of rRNA processing [GO:2000234]; rRNA methylation [GO:0031167]	protein methylation [GO:0006479]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]		18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity [GO:0052909]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]	methyltransferase activity [GO:0008168]
d1zqca1_d4i2ia1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1zqda1_d4qz9a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1zqna1_d1bpxa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d1zqna4_d1j0la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]		damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	
d1zqqa1_d4i2da1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d1zqqa4_d1tfyb2__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]		damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]
d1zqsa4_d4lt6b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d1zr0a__d2snva___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]
d1zr0a__d3gy2a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d1zr3b__d1yd9d___1	Metazoa	Metazoa	Chordata	Chordata	Barr body [GO:0001740]; condensed chromosome [GO:0000793]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; sex chromatin [GO:0001739]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; enzyme binding [GO:0019899]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]; chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of response to oxidative stress [GO:1902883]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of response to oxidative stress [GO:1902884]; regulation of gene expression, epigenetic [GO:0040029]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	Barr body [GO:0001740]; chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of response to oxidative stress [GO:1902883]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of response to oxidative stress [GO:1902884]; regulation of gene expression, epigenetic [GO:0040029]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	Barr body [GO:0001740]; condensed chromosome [GO:0000793]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; sex chromatin [GO:0001739]	Barr body [GO:0001740]; chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; enzyme binding [GO:0019899]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]	DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]
d1zr3c__d2vria___1	Metazoa		Chordata		Barr body [GO:0001740]; condensed chromosome [GO:0000793]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; sex chromatin [GO:0001739]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; enzyme binding [GO:0019899]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]; chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of response to oxidative stress [GO:1902883]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of response to oxidative stress [GO:1902884]; regulation of gene expression, epigenetic [GO:0040029]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of response to oxidative stress [GO:1902883]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of response to oxidative stress [GO:1902884]; regulation of gene expression, epigenetic [GO:0040029]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	Barr body [GO:0001740]; condensed chromosome [GO:0000793]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; sex chromatin [GO:0001739]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; enzyme binding [GO:0019899]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d1zr3d__d5cmse___1	Metazoa		Chordata	Proteobacteria	Barr body [GO:0001740]; condensed chromosome [GO:0000793]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; sex chromatin [GO:0001739]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; enzyme binding [GO:0019899]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]; chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of response to oxidative stress [GO:1902883]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of response to oxidative stress [GO:1902884]; regulation of gene expression, epigenetic [GO:0040029]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]; negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of response to oxidative stress [GO:1902883]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of response to oxidative stress [GO:1902884]; regulation of gene expression, epigenetic [GO:0040029]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	Barr body [GO:0001740]; condensed chromosome [GO:0000793]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; sex chromatin [GO:0001739]		chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; enzyme binding [GO:0019899]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]
d1zr4a2_d3pkzh___1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]; transposition [GO:0032196]	DNA integration [GO:0015074]	DNA integration [GO:0015074]; transposition [GO:0032196]			DNA binding [GO:0003677]; recombinase activity [GO:0000150]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]
d1zr4e2_d2rslc___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]	DNA integration [GO:0015074]	DNA integration [GO:0015074]			DNA binding [GO:0003677]; recombinase activity [GO:0000150]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]
d1zrcb2_d1omia1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; pathogenesis [GO:0009405]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	pathogenesis [GO:0009405]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d1zreb1_d3e5ud1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]
d1zrha__d2afhe___1	Metazoa		Chordata	Proteobacteria	Golgi lumen [GO:0005796]; [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity [GO:0008467]; sulfotransferase activity [GO:0008146]; glycosaminoglycan biosynthetic process [GO:0006024]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	glycosaminoglycan biosynthetic process [GO:0006024]	nitrogen fixation [GO:0009399]	Golgi lumen [GO:0005796]	molybdenum-iron nitrogenase complex [GO:0016612]	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity [GO:0008467]; sulfotransferase activity [GO:0008146]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d1zrka__d4mpva___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1zs0a__d4a7bb___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d1zs2a1_d9cgta3__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	amylosucrase activity [GO:0047669]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d1zs3b__d1fz1d___1				Proteobacteria		metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]		cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]				metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d1zs3e__d3a9qb___1		Viridiplantae		Streptophyta		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d1zs3f__d3e6ra___1				Bacillariophyta (diatoms)		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]
d1zs3h__d1mfrv___1		Metazoa		Chordata		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1zs3h__d3dhgd___1				Proteobacteria		oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]		toluene catabolic process [GO:0042203]				oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d1zs3i__d3uois___1				Actinobacteria		cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]		response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1zs3j__d5u1bd___1				Proteobacteria		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; efflux transmembrane transporter activity [GO:0015562]				integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		efflux transmembrane transporter activity [GO:0015562]
d1zs3l__d2yjjg___1				Actinobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		ferric iron binding [GO:0008199]
d1zs6a1_d3q8ve___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; apoptotic process [GO:0006915]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	apoptotic process [GO:0006915]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1zs6b__d5yolf___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; apoptotic process [GO:0006915]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	apoptotic process [GO:0006915]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1zs6d__d3mpdb___1	Metazoa	Fungi	Chordata	Microsporidia	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; apoptotic process [GO:0006915]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	apoptotic process [GO:0006915]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d1zs8b__d4laqh___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1zs8h__d3ikca1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1zs8j__d2r0wl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1zsda1_d4jr9l2__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; inorganic anion exchanger activity [GO:0005452]; nitrate transmembrane transporter activity [GO:0015112]; nitrite efflux transmembrane transporter activity [GO:0015514]; nitrate assimilation [GO:0042128]; nitrate transport [GO:0015706]; nitrite transport [GO:0015707]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	nitrate assimilation [GO:0042128]; nitrate transport [GO:0015706]; nitrite transport [GO:0015707]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	inorganic anion exchanger activity [GO:0005452]; nitrate transmembrane transporter activity [GO:0015112]; nitrite efflux transmembrane transporter activity [GO:0015514]
d1zsdb__d4rgmb2__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d1zsha1_d1nfid___1	Metazoa	Metazoa	Chordata	Chordata	clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; acetylcholine receptor binding [GO:0033130]; AP-2 adaptor complex binding [GO:0035612]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein homodimerization activity [GO:0042803]; clathrin-dependent endocytosis [GO:0072583]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	clathrin-dependent endocytosis [GO:0072583]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]	acetylcholine receptor binding [GO:0033130]; AP-2 adaptor complex binding [GO:0035612]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein homodimerization activity [GO:0042803]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d1zsja__d2nu0e___1	Metazoa		Chordata	Actinobacteria	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d1zspa2_d3esfd2__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1zspb2_d4gunc2__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1zsqa2_d1onya___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]; identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d1zsza1_d1ox9a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ribosome [GO:0005840]; positive regulation of protein catabolic process [GO:0045732]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; ribosome [GO:0005840]; ATPase binding [GO:0051117]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; positive regulation of ATPase activity [GO:0032781]; positive regulation of protein catabolic process [GO:0045732]	positive regulation of protein catabolic process [GO:0045732]	positive regulation of ATPase activity [GO:0032781]; positive regulation of protein catabolic process [GO:0045732]	cytosol [GO:0005829]; ribosome [GO:0005840]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; ribosome [GO:0005840]		ATPase binding [GO:0051117]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d1zszb1_d1ou8a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ribosome [GO:0005840]; positive regulation of protein catabolic process [GO:0045732]	cytosol [GO:0005829]; ribosome [GO:0005840]; positive regulation of protein catabolic process [GO:0045732]	positive regulation of protein catabolic process [GO:0045732]	positive regulation of protein catabolic process [GO:0045732]	cytosol [GO:0005829]; ribosome [GO:0005840]	cytosol [GO:0005829]; ribosome [GO:0005840]		
d1zt1b__d4xcnf1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1zt4a2_d1ld9a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1zt4b2_d4yhml1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1zt4c1_d1yjdl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; SH3/SH2 adaptor activity [GO:0005070]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cytokine biosynthetic process [GO:0042089]; humoral immune response [GO:0006959]; immune system process [GO:0002376]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of viral genome replication [GO:0045070]; regulation of defense response to virus by virus [GO:0050690]; regulation of regulatory T cell differentiation [GO:0045589]; regulatory T cell differentiation [GO:0045066]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cytokine biosynthetic process [GO:0042089]; humoral immune response [GO:0006959]; immune system process [GO:0002376]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of viral genome replication [GO:0045070]; regulation of defense response to virus by virus [GO:0050690]; regulation of regulatory T cell differentiation [GO:0045589]; regulatory T cell differentiation [GO:0045066]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; SH3/SH2 adaptor activity [GO:0005070]
d1zt4c2_d1klgb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d1zt4d2_d1a8jl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]
d1zt4d2_d3twcl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1zt7a1_d5iw1c1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1zt7c2_d2clza2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d1zt7d1_d2iamc1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1ztea1_d1n0na1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ztec2_d4f2ni2__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1zted1_d3c3sb1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1zted1_d4l2ca1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1ztga1_d1zzka2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; cadherin binding [GO:0045296]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; sequence-specific single stranded DNA binding [GO:0098847]; single-stranded DNA binding [GO:0003697]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA metabolic process [GO:0016070]; viral RNA genome replication [GO:0039694]	catalytic step 2 spliceosome [GO:0071013]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; podosome [GO:0002102]; cadherin binding [GO:0045296]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded DNA binding [GO:0003697]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045716]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902165]; regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter [GO:0072369]; regulation of low-density lipoprotein particle clearance [GO:0010988]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; signal transduction [GO:0007165]; viral process [GO:0016032]	mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA metabolic process [GO:0016070]; viral RNA genome replication [GO:0039694]	mRNA splicing, via spliceosome [GO:0000398]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045716]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902165]; regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter [GO:0072369]; regulation of low-density lipoprotein particle clearance [GO:0010988]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; signal transduction [GO:0007165]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	catalytic step 2 spliceosome [GO:0071013]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; podosome [GO:0002102]	cadherin binding [GO:0045296]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; sequence-specific single stranded DNA binding [GO:0098847]; single-stranded DNA binding [GO:0003697]	cadherin binding [GO:0045296]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded DNA binding [GO:0003697]
d1ztgb1_d2e3ua1__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; cadherin binding [GO:0045296]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; sequence-specific single stranded DNA binding [GO:0098847]; single-stranded DNA binding [GO:0003697]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA metabolic process [GO:0016070]; viral RNA genome replication [GO:0039694]	RNA binding [GO:0003723]	mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA metabolic process [GO:0016070]; viral RNA genome replication [GO:0039694]		cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]		cadherin binding [GO:0045296]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; sequence-specific single stranded DNA binding [GO:0098847]; single-stranded DNA binding [GO:0003697]	RNA binding [GO:0003723]
d1ztla__d3l3td___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; tertiary granule lumen [GO:1904724]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; antimicrobial humoral response [GO:0019730]; cobalamin metabolic process [GO:0009235]; digestion [GO:0007586]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	antimicrobial humoral response [GO:0019730]; cobalamin metabolic process [GO:0009235]; digestion [GO:0007586]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; tertiary granule lumen [GO:1904724]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d1ztxh1_d5b3jf2__1		Metazoa		Chordata	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; NMDA selective glutamate receptor complex [GO:0017146]; postsynaptic membrane [GO:0045211]; metal ion binding [GO:0046872]; NMDA glutamate receptor activity [GO:0004972]; protein heterotetramerization [GO:0051290]; response to zinc ion [GO:0010043]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	protein heterotetramerization [GO:0051290]; response to zinc ion [GO:0010043]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; NMDA selective glutamate receptor complex [GO:0017146]; postsynaptic membrane [GO:0045211]	protein dimerization activity [GO:0046983]	metal ion binding [GO:0046872]; NMDA glutamate receptor activity [GO:0004972]
d1ztxl2_d5w1wi1__1		Metazoa		Chordata	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	protein dimerization activity [GO:0046983]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1zuja1_d5v5kd___1				Euryarchaeota		cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]
d1zujc__d5d8xx___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d1zujd__d4u3ge___1				Proteobacteria		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d1zuoa1_d1i7kb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]	anaphase-promoting complex [GO:0005680]; cell [GO:0005623]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-protein transferase activity [GO:0004842]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; exit from mitosis [GO:0010458]; free ubiquitin chain polymerization [GO:0010994]; positive regulation of exit from mitosis [GO:0031536]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; ubiquitin-dependent protein catabolic process [GO:0006511]	protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; exit from mitosis [GO:0010458]; free ubiquitin chain polymerization [GO:0010994]; positive regulation of exit from mitosis [GO:0031536]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]	anaphase-promoting complex [GO:0005680]; cell [GO:0005623]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-protein transferase activity [GO:0004842]
d1zuob__d4x57a1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]	plasma membrane [GO:0005886]	protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]		cytosol [GO:0005829]	plasma membrane [GO:0005886]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]	
d1zuqa2_d1en4a2__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1zuqa2_d4f2nj2__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1zuqb1_d3ljfc1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d1zura__d1l69a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1zv2a2_d1zdsa2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d1zv5a1_d1q72l2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1zv5a1_d3oaul1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1zv5l__d1quda___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1zvfa1_d4hn0d1__1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]; 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; quinolinate metabolic process [GO:0046874]; tryptophan catabolic process [GO:0006569]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; antibiotic biosynthetic process [GO:0017000]; carbohydrate metabolic process [GO:0005975]	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; quinolinate metabolic process [GO:0046874]; tryptophan catabolic process [GO:0006569]	antibiotic biosynthetic process [GO:0017000]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d1zvfa1_d4hvoa___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]; 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; quinolinate metabolic process [GO:0046874]; tryptophan catabolic process [GO:0006569]	3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]; 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; quinolinate metabolic process [GO:0046874]; tryptophan catabolic process [GO:0006569]	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]	3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]
d1zvfb2_d4hsja___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]; 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; quinolinate metabolic process [GO:0046874]; tryptophan catabolic process [GO:0006569]	3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]; 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; quinolinate metabolic process [GO:0046874]; tryptophan catabolic process [GO:0006569]	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]	3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]
d1zvha1_d4gw1a1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d1zvka__d1gtj1___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1zvkb__d1gtg1___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d1zvmb__d3zwma___1	Metazoa	Metazoa	Chordata	Mollusca	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	cytoplasmic vesicle [GO:0031410]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]
d1zvob2_d1zlwl2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d1zvra1_d1k5de___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]; identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	dendritic spine maintenance [GO:0097062]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of endocytosis [GO:0045806]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; vacuolar membrane [GO:0005774]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	identical protein binding [GO:0042802]; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity [GO:0052629]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d1zvsa1_d3kpob1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d1zvsb__d2oqjb2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1zvsd1_d4dvbb1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d1zvse__d1ic4h___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d1zwha2_d3tuhb___1	Fungi	Metazoa	Ascomycota	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d1zwia1_d1ivlb___1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d1zwia2_d2nz9e1__1			Actinobacteria	Firmicutes	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]	voltage-gated potassium channel complex [GO:0008076]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d1zwib2_d1i1ca2__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	voltage-gated potassium channel complex [GO:0008076]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d1zwja2_d1gupd2__1	Viridiplantae		Streptophyta	Proteobacteria	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; galactose catabolic process via UDP-galactose [GO:0033499]	carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	galactose catabolic process via UDP-galactose [GO:0033499]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]	ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]
d1zwjb2_d5klyb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d1zwma1_d3so0d___1	Metazoa		Chordata	Firmicutes	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d1zwsb__d4bbeb___1	Metazoa	Metazoa	Chordata	Chordata	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]; anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	caveola [GO:0005901]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome lumen [GO:0031904]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; acetylcholine receptor binding [GO:0033130]; ATP binding [GO:0005524]; growth hormone receptor binding [GO:0005131]; heme binding [GO:0020037]; histone binding [GO:0042393]; histone kinase activity (H3-Y41 specific) [GO:0035401]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; interleukin-12 receptor binding [GO:0005143]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; type 1 angiotensin receptor binding [GO:0031702]; actin filament polymerization [GO:0030041]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activation of Janus kinase activity [GO:0042976]; activation of MAPKK activity [GO:0000186]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; axon regeneration [GO:0031103]; blood coagulation [GO:0007596]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; enzyme linked receptor protein signaling pathway [GO:0007167]; erythrocyte differentiation [GO:0030218]; extrinsic apoptotic signaling pathway [GO:0097191]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; histone H3-Y41 phosphorylation [GO:0035409]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; mammary gland epithelium development [GO:0061180]; MAPK cascade [GO:0000165]; mesoderm development [GO:0007498]; microglial cell activation [GO:0001774]; mineralocorticoid receptor signaling pathway [GO:0031959]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of DNA binding [GO:0043392]; negative regulation of heart contraction [GO:0045822]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell activation [GO:0050867]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial cell apoptotic process [GO:1904037]; positive regulation of growth factor dependent skeletal muscle satellite cell proliferation [GO:1902728]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; positive regulation of inflammatory response [GO:0050729]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; postsynapse to nucleus signaling pathway [GO:0099527]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of inflammatory response [GO:0050727]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; response to antibiotic [GO:0046677]; response to hydroperoxide [GO:0033194]; response to interleukin-12 [GO:0070671]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; tyrosine phosphorylation of STAT protein [GO:0007260]	anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	actin filament polymerization [GO:0030041]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activation of Janus kinase activity [GO:0042976]; activation of MAPKK activity [GO:0000186]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; axon regeneration [GO:0031103]; blood coagulation [GO:0007596]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; enzyme linked receptor protein signaling pathway [GO:0007167]; erythrocyte differentiation [GO:0030218]; extrinsic apoptotic signaling pathway [GO:0097191]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; histone H3-Y41 phosphorylation [GO:0035409]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; mammary gland epithelium development [GO:0061180]; MAPK cascade [GO:0000165]; mesoderm development [GO:0007498]; microglial cell activation [GO:0001774]; mineralocorticoid receptor signaling pathway [GO:0031959]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of heart contraction [GO:0045822]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell activation [GO:0050867]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial cell apoptotic process [GO:1904037]; positive regulation of growth factor dependent skeletal muscle satellite cell proliferation [GO:1902728]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; positive regulation of inflammatory response [GO:0050729]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; postsynapse to nucleus signaling pathway [GO:0099527]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of inflammatory response [GO:0050727]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; response to antibiotic [GO:0046677]; response to hydroperoxide [GO:0033194]; response to interleukin-12 [GO:0070671]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; tyrosine phosphorylation of STAT protein [GO:0007260]	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]	caveola [GO:0005901]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome lumen [GO:0031904]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]	acetylcholine receptor binding [GO:0033130]; ATP binding [GO:0005524]; growth hormone receptor binding [GO:0005131]; heme binding [GO:0020037]; histone binding [GO:0042393]; histone kinase activity (H3-Y41 specific) [GO:0035401]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; interleukin-12 receptor binding [GO:0005143]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; type 1 angiotensin receptor binding [GO:0031702]
d1zwsd__d1l8ta___1	Metazoa		Chordata	Firmicutes	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]; anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	ATP binding [GO:0005524]; kanamycin kinase activity [GO:0008910]; response to antibiotic [GO:0046677]	anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	response to antibiotic [GO:0046677]	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]		ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; kanamycin kinase activity [GO:0008910]
d1zwsf__d6aywa___1	Metazoa	Metazoa	Chordata	Chordata	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]; anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; sarcolemma [GO:0042383]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; sodium channel inhibitor activity [GO:0019871]; titin binding [GO:0031432]; cardiac muscle cell contraction [GO:0086003]; cellular response to calcium ion [GO:0071277]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of sodium ion transmembrane transport [GO:1902306]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1902514]; regulation of cardiac muscle cell action potential [GO:0098901]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cell growth [GO:0001558]; regulation of cellular localization [GO:0060341]; regulation of cellular response to heat [GO:1900034]; regulation of heart contraction [GO:0008016]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of histone deacetylase activity [GO:1901725]; regulation of membrane depolarization [GO:0003254]; regulation of relaxation of cardiac muscle [GO:1901897]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of the force of heart contraction [GO:0002026]; regulation of transcription by RNA polymerase II [GO:0006357]; relaxation of cardiac muscle [GO:0055119]	anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	cardiac muscle cell contraction [GO:0086003]; cellular response to calcium ion [GO:0071277]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of sodium ion transmembrane transport [GO:1902306]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1902514]; regulation of cardiac muscle cell action potential [GO:0098901]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cell growth [GO:0001558]; regulation of cellular localization [GO:0060341]; regulation of cellular response to heat [GO:1900034]; regulation of heart contraction [GO:0008016]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of histone deacetylase activity [GO:1901725]; regulation of membrane depolarization [GO:0003254]; regulation of relaxation of cardiac muscle [GO:1901897]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of the force of heart contraction [GO:0002026]; regulation of transcription by RNA polymerase II [GO:0006357]; relaxation of cardiac muscle [GO:0055119]	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; sarcolemma [GO:0042383]; sarcoplasmic reticulum membrane [GO:0033017]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; sodium channel inhibitor activity [GO:0019871]; titin binding [GO:0031432]
d1zwza1_d4af1a3__1	Fungi		Ascomycota	Euryarchaeota	box C/D snoRNP complex [GO:0031428]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511]; U4 snRNA binding [GO:0030621]; maturation of LSU-rRNA [GO:0000470]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of RNA binding [GO:1905216]; rRNA 2'-O-methylation [GO:0000451]; rRNA methylation [GO:0031167]	cytoplasm [GO:0005737]; translation release factor activity, codon specific [GO:0016149]	maturation of LSU-rRNA [GO:0000470]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of RNA binding [GO:1905216]; rRNA 2'-O-methylation [GO:0000451]; rRNA methylation [GO:0031167]		box C/D snoRNP complex [GO:0031428]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]	cytoplasm [GO:0005737]	RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511]; U4 snRNA binding [GO:0030621]	translation release factor activity, codon specific [GO:0016149]
d1zwzb1_d1pxwa___1	Fungi		Ascomycota	Euryarchaeota	box C/D snoRNP complex [GO:0031428]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511]; U4 snRNA binding [GO:0030621]; maturation of LSU-rRNA [GO:0000470]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of RNA binding [GO:1905216]; rRNA 2'-O-methylation [GO:0000451]; rRNA methylation [GO:0031167]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; ribosome biogenesis [GO:0042254]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	maturation of LSU-rRNA [GO:0000470]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of RNA binding [GO:1905216]; rRNA 2'-O-methylation [GO:0000451]; rRNA methylation [GO:0031167]	ribosome biogenesis [GO:0042254]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	box C/D snoRNP complex [GO:0031428]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]	RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511]; U4 snRNA binding [GO:0030621]	ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d1zx0b__d5gozc___1						extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d1zx1b__d2ohhb2__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d1zxib1_d2w3sf1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1zxic2_d3etrb1__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1zxic2_d4o95a1__1		Viridiplantae	Proteobacteria	Streptophyta	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]		cytokinin metabolic process [GO:0009690]			2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]
d1zxid1_d1jrog1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d1zxif1_d3nrzb2__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d1zxza1_d3k6lb___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; mitochondrion [GO:0005739]; plant-type cell wall [GO:0009505]; metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; co-translational protein modification [GO:0043686]; translation [GO:0006412]	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; mitochondrion [GO:0005739]; plant-type cell wall [GO:0009505]	cytosol [GO:0005829]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]	ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]
d1zy1b1_d2os3a1__1	Viridiplantae		Streptophyta	Firmicutes	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; mitochondrion [GO:0005739]; plant-type cell wall [GO:0009505]; metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; co-translational protein modification [GO:0043686]; translation [GO:0006412]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; translation [GO:0006412]	translation [GO:0006412]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; mitochondrion [GO:0005739]; plant-type cell wall [GO:0009505]		metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d1zyao2_d4r5ha2__1												
d1zyaq2_d3idsd2__1						glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		glycosome [GO:0020015]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d1zyar2_d1e5qh2__1		Fungi		Ascomycota		saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]; lysine biosynthetic process via aminoadipic acid [GO:0019878]		lysine biosynthetic process via aminoadipic acid [GO:0019878]				saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]
d1zyee1_d1a8ya1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of store-operated calcium channel activity [GO:1901341]; protein polymerization [GO:0051258]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of store-operated calcium entry [GO:2001256]; sarcomere organization [GO:0045214]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of store-operated calcium channel activity [GO:1901341]; protein polymerization [GO:0051258]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of store-operated calcium entry [GO:2001256]; sarcomere organization [GO:0045214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]	calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]
d1zyef1_d2h76a___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1zyeg1_d4xs1d___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytosol [GO:0005829]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]	thioredoxin peroxidase activity [GO:0008379]
d1zyei1_d5aisc1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d1zyka1_d2wk5b1__1		Metazoa	Crenarchaeota	Chordata	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	tryptophan biosynthetic process [GO:0000162]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	cytosol [GO:0005829]	cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1zykb1_d4lhma1__1			Crenarchaeota	Proteobacteria	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; membrane [GO:0016020]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]	tryptophan biosynthetic process [GO:0000162]	cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1zykb1_d5ep8a1__1			Crenarchaeota	Firmicutes	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	tryptophan biosynthetic process [GO:0000162]	pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	cytosol [GO:0005829]	cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1zykc1_d1uoua1__1		Metazoa	Crenarchaeota	Chordata	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	tryptophan biosynthetic process [GO:0000162]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	cytosol [GO:0005829]	cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1zykc1_d4yyyb1__1			Crenarchaeota	Proteobacteria	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]	tryptophan biosynthetic process [GO:0000162]	pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]	cytosol [GO:0005829]	cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d1zyna1_d1zyna2__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]	cell [GO:0005623]	alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]	alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]
d1zynb1_d1v98a___1			Proteobacteria	Deinococcus-Thermus	cell [GO:0005623]; alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]	cell [GO:0005623]	alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]
d1zynb2_d2eiob___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d1zynb2_d2kp1a1__1		Fungi	Proteobacteria	Ascomycota	cell [GO:0005623]; alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]	alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide isomerase activity [GO:0003756]
d1zypa2_d5enub___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]
d1zypb1_d1a8la1__1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]
d1zyqb__d4zbda1__1		Fungi	Proteobacteria	Basidiomycota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	
d1zyrf3_d4g7hp1__1			Deinococcus-Thermus	Deinococcus-Thermus	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]			DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d1zyrk2_d1ynjb2__1			Deinococcus-Thermus	Deinococcus-Thermus	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]; transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]			DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]
d1zyrp3_d1h3lb___1			Deinococcus-Thermus	Actinobacteria	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]; DNA-templated transcription, initiation [GO:0006352]; response to oxidative stress [GO:0006979]	transcription, DNA-templated [GO:0006351]	DNA-templated transcription, initiation [GO:0006352]; response to oxidative stress [GO:0006979]			DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]
d1zyta__d1g06a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d1zyua__d2pt7d___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	type IV secretion system complex [GO:0043684]; nucleotide binding [GO:0000166]; secretion by the type IV secretion system [GO:0044097]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	secretion by the type IV secretion system [GO:0044097]	cytosol [GO:0005829]	type IV secretion system complex [GO:0043684]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]	nucleotide binding [GO:0000166]
d1zz7a1_d3jxbc___1			Actinobacteria		dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	DNA binding [GO:0003677]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]				dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]	DNA binding [GO:0003677]
d1zz8b2_d2ixlc___1			Actinobacteria	Firmicutes	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]				dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d1zz9a1_d2gzub___1			Actinobacteria	Firmicutes	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	DNA binding [GO:0003677]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]				dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]	DNA binding [GO:0003677]
d1zz9b1_d2aw6a1__1			Actinobacteria	Firmicutes	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	transcriptional repressor complex [GO:0017053]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	negative regulation of transcription, DNA-templated [GO:0045892]		transcriptional repressor complex [GO:0017053]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]	DNA binding [GO:0003677]
d1zzba1_d3g5gf___1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	DNA binding [GO:0003677]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]				dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]	DNA binding [GO:0003677]
d1zzeb__d3etef2__1	Fungi	Metazoa	Basidiomycota	Chordata	alcohol dehydrogenase (NADP+) activity [GO:0008106]; coenzyme binding [GO:0050662]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; coenzyme binding [GO:0050662]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d1zzeb__d5jfoa___1	Fungi		Basidiomycota	Actinobacteria	alcohol dehydrogenase (NADP+) activity [GO:0008106]; coenzyme binding [GO:0050662]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; coenzyme binding [GO:0050662]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d1zzwa__d2b4oa___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; JUN kinase binding [GO:0008432]; MAP kinase phosphatase activity [GO:0033549]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; mitogen-activated protein kinase p38 binding [GO:0048273]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelium regeneration [GO:1905042]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; oligodendrocyte differentiation [GO:0048709]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein dephosphorylation [GO:0006470]; regulation of adaptive immune response [GO:0002819]; regulation of brown fat cell differentiation [GO:0090335]; response to lipopolysaccharide [GO:0032496]	protein tyrosine phosphatase activity [GO:0004725]	dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelium regeneration [GO:1905042]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; oligodendrocyte differentiation [GO:0048709]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein dephosphorylation [GO:0006470]; regulation of adaptive immune response [GO:0002819]; regulation of brown fat cell differentiation [GO:0090335]; response to lipopolysaccharide [GO:0032496]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		JUN kinase binding [GO:0008432]; MAP kinase phosphatase activity [GO:0033549]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; mitogen-activated protein kinase p38 binding [GO:0048273]; phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d1zzyb__d2dj2a1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; melanosome [GO:0042470]; smooth endoplasmic reticulum [GO:0005790]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]; chaperone-mediated protein folding [GO:0061077]; positive regulation of protein folding [GO:1903334]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; chaperone-mediated protein folding [GO:0061077]; positive regulation of protein folding [GO:1903334]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; melanosome [GO:0042470]; smooth endoplasmic reticulum [GO:0005790]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide isomerase activity [GO:0003756]
d208la__d1ljjb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d208la__d5jgxa___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d209la__d5gwba___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d20gsa2_d4gtub2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; long-chain fatty acid biosynthetic process [GO:0042759]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; long-chain fatty acid biosynthetic process [GO:0042759]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d20gsa2_d4hqza___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]
d216la__d1jsfa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d217la__d1g0qa___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d21gsb3_d3dvwa___1				Proteobacteria		cell [GO:0005623]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]		
d221la__d5kgra___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d224la__d1c6ja___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d224la__d1hkec___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]	
d226la__d3wu7a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d227la__d2qarf___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d22gsb1_d1glpb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]
d22gsb2_d1oe7b2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d22gsb2_d2vcvc1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d230la__d2hs7a1__1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d231la__d3aggg___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d234la__d5k2sa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d235la__d256la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d236la__d211la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d236la__d4gn3e___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d237la__d250la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d240la__d1lj4a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d240la__d3lzma___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d241la__d5ki1a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d242la__d1uica___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d243la__d4b4ja___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d244la__d4n9ra___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d245la__d1op9b___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d248la__d3dn2a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d249la__d142la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d250la__d3m18b___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d252la__d1iy4a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d254la__d1cu6a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d254la__d1ljhb___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d25c8h2_d1ymhd1__1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]
d25c8l1_d3grwl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d261la__d1gbxa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2a03a2_d1ix9b2__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2a03b1_d1en6d1__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2a06b2_d1q2la3__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	proteolysis [GO:0006508]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d2a06d1_d3l71q1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d2a06n2_d1sqvb1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d2a06n2_d3l71b2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d2a07j__d1smtb___1	Metazoa		Chordata	Cyanobacteria	nuclear chromatin [GO:0000790]; androgen receptor binding [GO:0050681]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; camera-type eye development [GO:0043010]; caudate nucleus development [GO:0021757]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; innate vocalization behavior [GO:0098582]; lung alveolus development [GO:0048286]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of mesenchymal cell proliferation [GO:0002053]; post-embryonic development [GO:0009791]; putamen development [GO:0021758]; response to testosterone [GO:0033574]; righting reflex [GO:0060013]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; vocal learning [GO:0042297]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]	camera-type eye development [GO:0043010]; caudate nucleus development [GO:0021757]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; innate vocalization behavior [GO:0098582]; lung alveolus development [GO:0048286]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of mesenchymal cell proliferation [GO:0002053]; post-embryonic development [GO:0009791]; putamen development [GO:0021758]; response to testosterone [GO:0033574]; righting reflex [GO:0060013]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; vocal learning [GO:0042297]		nuclear chromatin [GO:0000790]		androgen receptor binding [GO:0050681]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]
d2a0fb1_d5at1b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2a0lf1_d2hwzl2__1			Crenarchaeota		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]; regulation of ion transmembrane transport [GO:0034765]		regulation of ion transmembrane transport [GO:0034765]		voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2a10a1_d4rbuf___1			Cyanobacteria	Proteobacteria								
d2a10d__d3ssqd___1			Cyanobacteria	Cyanobacteria		identical protein binding [GO:0042802]						identical protein binding [GO:0042802]
d2a14a1_d1n7ja___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amine N-methyltransferase activity [GO:0030748]; S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity [GO:0102707]; thioether S-methyltransferase activity [GO:0004790]; amine metabolic process [GO:0009308]; methylation [GO:0032259]; response to toxic substance [GO:0009636]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	amine metabolic process [GO:0009308]; methylation [GO:0032259]; response to toxic substance [GO:0009636]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amine N-methyltransferase activity [GO:0030748]; S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity [GO:0102707]; thioether S-methyltransferase activity [GO:0004790]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d2a18b__d3ssqc___1			Cyanobacteria	Cyanobacteria		identical protein binding [GO:0042802]						identical protein binding [GO:0042802]
d2a1bc__d4ox8b___1			Cyanobacteria	Cyanobacteria								
d2a1be__d4ox7c___1			Cyanobacteria	Cyanobacteria								
d2a1be__d4p7ta___1			Cyanobacteria	Proteobacteria								
d2a1bf__d4qifg___1			Cyanobacteria	Proteobacteria								
d2a1bg__d3paca1__1			Cyanobacteria	Proteobacteria								
d2a1bh__d4ppdd___1			Cyanobacteria	Proteobacteria								
d2a1bi__d4p2se___1			Cyanobacteria									
d2a1bk__d2a10b___1			Cyanobacteria	Cyanobacteria								
d2a1bk__d5l38k___1			Cyanobacteria	Actinobacteria								
d2a1ea__d2qk5b___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d2a1ma__d4iq9a___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]
d2a1na__d1j51b___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	(+)-camphor catabolic process [GO:0019383]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2a1na__d2ve4b___1			Proteobacteria	Cyanobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	C-22 sterol desaturase activity [GO:0000249]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; ergosterol biosynthetic process [GO:0006696]; oxidation-reduction process [GO:0055114]; sterol metabolic process [GO:0016125]	(+)-camphor catabolic process [GO:0019383]	ergosterol biosynthetic process [GO:0006696]; oxidation-reduction process [GO:0055114]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	C-22 sterol desaturase activity [GO:0000249]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]
d2a1nb__d3g1qd___1			Proteobacteria		cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	(+)-camphor catabolic process [GO:0019383]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d2a1nb__d5xhja___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d2a1ob__d2qbma___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	(+)-camphor catabolic process [GO:0019383]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2a1ob__d4j6ca___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2a1td1_d1egcb1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	electron transfer activity [GO:0009055]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]
d2a1tr2_d1mczj1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	mandelate catabolic process [GO:0019596]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2a1wl1_d4y5xd___1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]		brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]		extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]
d2a1wl2_d2hvka2__1	Metazoa		Chordata	Actinobacteria	metal ion binding [GO:0046872]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d2a24b__d2owja___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	integral component of plasma membrane [GO:0005887]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d2a2ad__d5j87a___1	Metazoa	Metazoa	Chordata	Chordata	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]; anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein tyrosine kinase activity [GO:0004713]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; B cell affinity maturation [GO:0002344]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; cell maturation [GO:0048469]; cellular response to interleukin-7 [GO:0098761]; cellular response to molecule of fungal origin [GO:0071226]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; histamine secretion by mast cell [GO:0002553]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; mesoderm development [GO:0007498]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cytokine production [GO:0001818]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type III hypersensitivity [GO:0001805]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of B cell apoptotic process [GO:0002902]; regulation of B cell cytokine production [GO:0002721]	anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; B cell affinity maturation [GO:0002344]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; cell maturation [GO:0048469]; cellular response to interleukin-7 [GO:0098761]; cellular response to molecule of fungal origin [GO:0071226]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; histamine secretion by mast cell [GO:0002553]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; mesoderm development [GO:0007498]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cytokine production [GO:0001818]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type III hypersensitivity [GO:0001805]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of B cell apoptotic process [GO:0002902]; regulation of B cell cytokine production [GO:0002721]	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein tyrosine kinase activity [GO:0004713]
d2a2gd__d3kfha___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]
d2a2rb2_d3i6ac1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2a2ub__d2mo5a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cytosol [GO:0005829]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytosol [GO:0005829]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]
d2a31a__d1ij7c___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	
d2a32a__d1ep5a___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; suppression by virus of host gene expression [GO:0039657]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2a38a1_d2vq1e2__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2a38b2_d5e0qa___1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	nuclear pore cytoplasmic filaments [GO:0044614]; nuclear localization sequence binding [GO:0008139]; RNA binding [GO:0003723]; structural constituent of nuclear pore [GO:0017056]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; telomere tethering at nuclear periphery [GO:0034398]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; telomere tethering at nuclear periphery [GO:0034398]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	nuclear pore cytoplasmic filaments [GO:0044614]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	nuclear localization sequence binding [GO:0008139]; RNA binding [GO:0003723]; structural constituent of nuclear pore [GO:0017056]
d2a38c1_d4l4tg1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2a38c2_d5ja9b1__1	Metazoa		Chordata	Proteobacteria	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	
d2a39a__d3nwkb___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		cellulase activity [GO:0008810]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2a39b__d3b9ca___1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cytoplasm [GO:0005737]; intracellular [GO:0005622]; carbohydrate binding [GO:0030246]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	cytoplasm [GO:0005737]; intracellular [GO:0005622]	cellulase activity [GO:0008810]	carbohydrate binding [GO:0030246]
d2a3fx2_d1u18b___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	vasodilation [GO:0042311]	vasodilation [GO:0042311]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]
d2a3fx2_d3mbta___1	Metazoa		Arthropoda	Proteobacteria	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	cell outer membrane [GO:0009279]; cytoplasm [GO:0005737]; lipid binding [GO:0008289]; cellular response to DNA damage stimulus [GO:0006974]; lipid metabolic process [GO:0006629]; response to reactive oxygen species [GO:0000302]	vasodilation [GO:0042311]	cellular response to DNA damage stimulus [GO:0006974]; lipid metabolic process [GO:0006629]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]	cell outer membrane [GO:0009279]; cytoplasm [GO:0005737]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	lipid binding [GO:0008289]
d2a3ha__d1jyyc5__1			Firmicutes		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	
d2a3ia__d3wfga___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; receptor complex [GO:0043235]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; receptor complex [GO:0043235]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]	positive regulation of NIK/NF-kappaB signaling [GO:1901224]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]	positive regulation of NIK/NF-kappaB signaling [GO:1901224]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; receptor complex [GO:0043235]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; receptor complex [GO:0043235]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]
d2a3rb__d3sjya1__1	Metazoa		Chordata		cytosol [GO:0005829]; amine sulfotransferase activity [GO:0047685]; aryl sulfotransferase activity [GO:0004062]; sulfate binding [GO:0043199]; sulfotransferase activity [GO:0008146]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; calcineurin-mediated signaling [GO:0097720]; cellular response to dopamine [GO:1903351]; dopamine catabolic process [GO:0042420]; dopamine receptor signaling pathway [GO:0007212]; ERK1 and ERK2 cascade [GO:0070371]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of neuron death [GO:1901215]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]		3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; calcineurin-mediated signaling [GO:0097720]; cellular response to dopamine [GO:1903351]; dopamine catabolic process [GO:0042420]; dopamine receptor signaling pathway [GO:0007212]; ERK1 and ERK2 cascade [GO:0070371]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of neuron death [GO:1901215]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]		amine sulfotransferase activity [GO:0047685]; aryl sulfotransferase activity [GO:0004062]; sulfate binding [GO:0043199]; sulfotransferase activity [GO:0008146]	
d2a3ta1_d2p80b2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2a3ta2_d1zdqa2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2a3wa__d1valc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2a3we__d1cr7g___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2a3wf__d3pvng___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d2a3wf__d5glvb1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]
d2a3wi__d1g8wd___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	mannose binding [GO:0005537]; toxin activity [GO:0090729]; defense response [GO:0006952]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	defense response [GO:0006952]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	mannose binding [GO:0005537]; toxin activity [GO:0090729]
d2a3wj__d1sfyd___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]
d2a3wl__d4pbpb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	metal ion binding [GO:0046872]
d2a3wo__d5duxb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	cell adhesion [GO:0007155]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2a3wp__d2e53a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]
d2a3wr__d4p9xd___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2a3xb__d5nfba___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d2a3xc__d1gnhe___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d2a3xe__d1qf3c___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2a3xf__d1enra___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2a3xi__d5t54b___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2a3xj__d1oa3c___1	Metazoa	Fungi	Chordata	Ascomycota	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	polysaccharide catabolic process [GO:0000272]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	cellulase activity [GO:0008810]
d2a3ya__d5ca6a___1	Metazoa		Chordata		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	viral capsid [GO:0019028]; viral life cycle [GO:0019058]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	viral life cycle [GO:0019058]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	viral capsid [GO:0019028]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	
d2a3yc__d1n47b___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2a3yd__d5gj6d___1	Metazoa		Chordata		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	
d2a3za2_d2ch6c1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]; apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]	N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]	ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]
d2a40a2_d1huxa___1	Metazoa		Chordata	Firmicutes	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; metal ion binding [GO:0046872]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d2a40d2_d2zf5y1__1	Metazoa		Chordata	Euryarchaeota	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cytosol [GO:0005829]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d2a42a2_d2e20a1__1	Metazoa		Chordata	Proteobacteria	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]; L-threonine catabolic process to propionate [GO:0070689]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	L-threonine catabolic process to propionate [GO:0070689]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]
d2a45.1_d4inla___1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular region [GO:0005576]; serine-type peptidase activity [GO:0008236]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	serine-type peptidase activity [GO:0008236]
d2a4ca1_d2o72a2__1	Metazoa	Metazoa	Chordata	Chordata	catenin complex [GO:0016342]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; corticospinal tract morphogenesis [GO:0021957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; corticospinal tract morphogenesis [GO:0021957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2a4cb1_d3lnea2__1	Metazoa	Metazoa	Chordata	Chordata	catenin complex [GO:0016342]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; corticospinal tract morphogenesis [GO:0021957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; corticospinal tract morphogenesis [GO:0021957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d2a4cb1_d4zmpa2__1	Metazoa	Metazoa	Chordata	Chordata	catenin complex [GO:0016342]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; corticospinal tract morphogenesis [GO:0021957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; corticospinal tract morphogenesis [GO:0021957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d2a4da1_d2onua___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; UBC13-UEV1A complex [GO:0035370]; ubiquitin conjugating enzyme complex [GO:0031371]; ubiquitin ligase complex [GO:0000151]; ubiquitin conjugating enzyme activity [GO:0061631]; activation of MAPK activity [GO:0000187]; cell differentiation [GO:0030154]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription, DNA-templated [GO:0045893]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; regulation of DNA repair [GO:0006282]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; cell differentiation [GO:0030154]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription, DNA-templated [GO:0045893]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; regulation of DNA repair [GO:0006282]; regulation of transcription, DNA-templated [GO:0006355]	ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; UBC13-UEV1A complex [GO:0035370]; ubiquitin conjugating enzyme complex [GO:0031371]; ubiquitin ligase complex [GO:0000151]		ubiquitin conjugating enzyme activity [GO:0061631]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]
d2a4mb__d1jika___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	tryptophanyl-tRNA aminoacylation [GO:0006436]	tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]
d2a4na__d2z0za___1			Firmicutes	Deinococcus-Thermus	N-acetyltransferase activity [GO:0008080]	identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]					N-acetyltransferase activity [GO:0008080]	identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]
d2a4oa__d1op0a___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]
d2a4xa2_d1mh6b___1			Actinobacteria	Proteobacteria		drug binding [GO:0008144]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]				drug binding [GO:0008144]
d2a57a__d1kz9d___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]
d2a57b__d2obxc___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d2a58b__d1kyye___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin binding [GO:1902444]
d2a5aa__d5dp3a1__1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2a5bb__d1swjb___1	Metazoa		Chordata	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]; antibacterial humoral response [GO:0019731]	extracellular region [GO:0005576]; biotin binding [GO:0009374]	antibacterial humoral response [GO:0019731]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2a5da__d1g64b___1	Metazoa		Chordata	Proteobacteria	cell cortex [GO:0005938]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; recycling endosome membrane [GO:0055038]; ruffle [GO:0001726]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein N-terminus binding [GO:0047485]; thioesterase binding [GO:0031996]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to nerve growth factor stimulus [GO:1990090]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; intracellular protein transport [GO:0006886]; liver development [GO:0001889]; maintenance of postsynaptic density structure [GO:0099562]; myeloid cell apoptotic process [GO:0033028]; negative regulation of dendrite development [GO:2000171]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of receptor-mediated endocytosis [GO:0048261]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of presynapse assembly [GO:1905606]; regulation of Rac protein signal transduction [GO:0035020]; ruffle assembly [GO:0097178]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]; cobalamin biosynthetic process [GO:0009236]; porphyrin-containing compound biosynthetic process [GO:0006779]	cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to nerve growth factor stimulus [GO:1990090]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; intracellular protein transport [GO:0006886]; liver development [GO:0001889]; maintenance of postsynaptic density structure [GO:0099562]; myeloid cell apoptotic process [GO:0033028]; negative regulation of dendrite development [GO:2000171]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of receptor-mediated endocytosis [GO:0048261]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of presynapse assembly [GO:1905606]; regulation of Rac protein signal transduction [GO:0035020]; ruffle assembly [GO:0097178]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192]	cobalamin biosynthetic process [GO:0009236]; porphyrin-containing compound biosynthetic process [GO:0006779]	cell cortex [GO:0005938]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; recycling endosome membrane [GO:0055038]; ruffle [GO:0001726]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein N-terminus binding [GO:0047485]; thioesterase binding [GO:0031996]	ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]
d2a5ia__d2zecb___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2a5ma1_d1m8ua1__1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d2a5ma2_d1elpa2__1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d2a5xa2_d1x9jd2__1	Metazoa		Chordata	Thermotogae	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cytoplasm [GO:0005737]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]
d2a61a1_d5hs8a1__1			Thermotogae	Firmicutes	DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; regulation of transcription, DNA-templated [GO:0006355]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]	regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]		protein-DNA complex [GO:0032993]	DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]	DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2a6db3_d1lo4h2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2a6el2_d2ja5c2__1		Fungi	Deinococcus-Thermus	Ascomycota	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	transcription, DNA-templated [GO:0006351]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]		cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]
d2a6hk2_d3s14c2__1		Fungi	Deinococcus-Thermus	Ascomycota	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	transcription, DNA-templated [GO:0006351]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]		cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]
d2a6ib3_d4krlb___1		Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2a6jh3_d1nc4b1__1												
d2a6jl2_d1fn4d2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2a6jl2_d2rcjj1__1		Metazoa		Chordata								
d2a6kh3_d5e5rb2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	anchored component of membrane [GO:0031225]; plasma membrane [GO:0005886]; cell adhesion [GO:0007155]; nervous system development [GO:0007399]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell adhesion [GO:0007155]; nervous system development [GO:0007399]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	anchored component of membrane [GO:0031225]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2a6la1_d3daqc___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d2a6pb__d2enua___1			Actinobacteria	Deinococcus-Thermus		catalytic activity [GO:0003824]						catalytic activity [GO:0003824]
d2a6rd__d4ml0l___1			Proteobacteria	Proteobacteria	endoribonuclease activity [GO:0004521]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; mRNA catabolic process [GO:0006402]; mRNA cleavage involved in gene silencing [GO:0098795]; negative regulation of translational initiation [GO:0045947]; RNA catabolic process [GO:0006401]; single-species biofilm formation [GO:0044010]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; toxic substance binding [GO:0015643]; regulation of transcription, DNA-templated [GO:0006355]; single-species biofilm formation [GO:0044010]	mRNA catabolic process [GO:0006402]; mRNA cleavage involved in gene silencing [GO:0098795]; negative regulation of translational initiation [GO:0045947]; RNA catabolic process [GO:0006401]; single-species biofilm formation [GO:0044010]	regulation of transcription, DNA-templated [GO:0006355]; single-species biofilm formation [GO:0044010]			endoribonuclease activity [GO:0004521]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; toxic substance binding [GO:0015643]
d2a6vb__d3lcpa___1	Fungi	Metazoa	Ascomycota	Chordata	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]	endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; calcium ion binding [GO:0005509]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]	endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]	COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]	endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]
d2a6wb__d2phfb___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]		COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]		carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2a6xa1_d4gkxe___1	Fungi	Metazoa	Ascomycota	Chordata	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]	collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; sarcomere [GO:0030017]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; blood coagulation [GO:0007596]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; negative regulation of protein targeting to mitochondrion [GO:1903215]; positive regulation of organelle organization [GO:0010638]; protein folding [GO:0006457]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]	endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]	blood coagulation [GO:0007596]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; negative regulation of protein targeting to mitochondrion [GO:1903215]; positive regulation of organelle organization [GO:0010638]; protein folding [GO:0006457]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]	collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; sarcomere [GO:0030017]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d2a6xb__d1v6mb___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]		COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]		carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2a70a2_d5glta2__1	Fungi	Metazoa	Ascomycota	Nematoda (roundworms)	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; fungal-type vacuole membrane [GO:0000329]; Golgi membrane [GO:0000139]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]; carbohydrate derivative binding [GO:0097367]; mannose binding [GO:0005537]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]	carbohydrate binding [GO:0030246]	endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]		COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; fungal-type vacuole membrane [GO:0000329]; Golgi membrane [GO:0000139]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]		carbohydrate derivative binding [GO:0097367]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]
d2a71b__d1n47d___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; fungal-type vacuole membrane [GO:0000329]; Golgi membrane [GO:0000139]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]; carbohydrate derivative binding [GO:0097367]; mannose binding [GO:0005537]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]		COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; fungal-type vacuole membrane [GO:0000329]; Golgi membrane [GO:0000139]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]		carbohydrate derivative binding [GO:0097367]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2a71d__d3vzna___1	Fungi		Ascomycota	Firmicutes	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; fungal-type vacuole membrane [GO:0000329]; Golgi membrane [GO:0000139]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]; carbohydrate derivative binding [GO:0097367]; mannose binding [GO:0005537]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]	xylan catabolic process [GO:0045493]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; fungal-type vacuole membrane [GO:0000329]; Golgi membrane [GO:0000139]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]		carbohydrate derivative binding [GO:0097367]; mannose binding [GO:0005537]	endo-1,4-beta-xylanase activity [GO:0031176]
d2a72a1_d1fqje___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; plasma membrane [GO:0005886]; G-protein beta-subunit binding [GO:0031681]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; protein folding [GO:0006457]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; protein folding [GO:0006457]	adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	G-protein beta-subunit binding [GO:0031681]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d2a73a2_d3cu7a3__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d2a73a4_d2a73.1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d2a73a4_d3cu7b4__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d2a73a5_d3cu7a4__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d2a73a5_d3cu7a5__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d2a77h1_d5wkea2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2a78b__d3ce0a2__1		Metazoa		Chordata	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; catalytic activity [GO:0003824]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	extracellular region [GO:0005576]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]	transferase activity, transferring pentosyl groups [GO:0016763]	catalytic activity [GO:0003824]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]
d2a7ba__d2e9ga1__1	Metazoa	Metazoa	Chordata	Chordata	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]; collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	AP-1 adaptor complex [GO:0030121]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle [GO:0005798]; membrane [GO:0016020]; transport vesicle [GO:0030133]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]	AP-1 adaptor complex [GO:0030121]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; transport vesicle [GO:0030133]	collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]	
d2a7ge__d5cuha1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]		cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d2a7ix__d5lh3a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]			cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]		
d2a7ja__d5gpif___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2a7kc__d3r9sa___1			Proteobacteria	Actinobacteria	transferase activity [GO:0016740]; antibiotic biosynthetic process [GO:0017000]	catalytic activity [GO:0003824]	antibiotic biosynthetic process [GO:0017000]				transferase activity [GO:0016740]	catalytic activity [GO:0003824]
d2a7kf__d3mt6m___1			Proteobacteria	Proteobacteria	transferase activity [GO:0016740]; antibiotic biosynthetic process [GO:0017000]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	antibiotic biosynthetic process [GO:0017000]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	transferase activity [GO:0016740]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2a7lb2_d4v3ka___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular response to misfolded protein [GO:0071218]; DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein monoubiquitination [GO:0006513]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular response to misfolded protein [GO:0071218]; DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein monoubiquitination [GO:0006513]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; protein ubiquitination [GO:0016567]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2a7na__d4jgda___1		Metazoa	Proteobacteria	Chordata	membrane [GO:0016020]; (S)-mandelate dehydrogenase activity [GO:0033720]; FMN binding [GO:0010181]; mandelate catabolic process [GO:0019596]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]	mandelate catabolic process [GO:0019596]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]	membrane [GO:0016020]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]	(S)-mandelate dehydrogenase activity [GO:0033720]; FMN binding [GO:0010181]	dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]
d2a7sa1_d3trrb___1			Actinobacteria	Actinobacteria	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	isomerase activity [GO:0016853]	carbon fixation [GO:0015977]		acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]	isomerase activity [GO:0016853]
d2a7sc1_d4i52e___1			Actinobacteria	Cyanobacteria	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; menaquinone biosynthetic process [GO:0009234]; phylloquinone biosynthetic process [GO:0042372]	carbon fixation [GO:0015977]	menaquinone biosynthetic process [GO:0009234]; phylloquinone biosynthetic process [GO:0042372]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]	1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]
d2a7sc2_d3tvub1__1		Fungi	Actinobacteria	Ascomycota	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	carbon fixation [GO:0015977]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d2a7sc2_d4qijc___1			Actinobacteria	Actinobacteria	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; 1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; menaquinone biosynthetic process [GO:0009234]; protein hexamerization [GO:0034214]	carbon fixation [GO:0015977]	menaquinone biosynthetic process [GO:0009234]; protein hexamerization [GO:0034214]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]	1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]
d2a7sd1_d1jxza___1			Actinobacteria	Proteobacteria	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	4-chlorobenzoyl-CoA dehalogenase activity [GO:0018787]; coenzyme A metabolic process [GO:0015936]	carbon fixation [GO:0015977]	coenzyme A metabolic process [GO:0015936]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]	4-chlorobenzoyl-CoA dehalogenase activity [GO:0018787]
d2a7sd2_d1uyrb1__1		Fungi	Actinobacteria	Ascomycota	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	carbon fixation [GO:0015977]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d2a7se1_d5dtwf1__1			Actinobacteria	Actinobacteria	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	carbon fixation [GO:0015977]	fatty acid beta-oxidation [GO:0006635]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]
d2a7sf1_d1yg6n___1			Actinobacteria	Proteobacteria	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	carbon fixation [GO:0015977]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2a83a1_d5whkl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2a85a__d3hgjc___1			Proteobacteria	Deinococcus-Thermus	membrane [GO:0016020]; (S)-mandelate dehydrogenase activity [GO:0033720]; FMN binding [GO:0010181]; mandelate catabolic process [GO:0019596]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	mandelate catabolic process [GO:0019596]		membrane [GO:0016020]		(S)-mandelate dehydrogenase activity [GO:0033720]; FMN binding [GO:0010181]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d2a89b2_d2f5va2__1		Fungi	Firmicutes	Basidiomycota	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	periplasmic space [GO:0042597]; flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	tetrahydrofolate metabolic process [GO:0046653]		cytoplasm [GO:0005737]	periplasmic space [GO:0042597]	sarcosine oxidase activity [GO:0008115]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]
d2a8cd__d3lasa___1			Proteobacteria	Firmicutes	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbon utilization [GO:0015976]				carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2a8db__d4wajb___1			Proteobacteria	Proteobacteria	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbon utilization [GO:0015976]	carbon utilization [GO:0015976]			carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2a8ha__d4r7la2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2a8kb__d1tfka___1			Proteobacteria	Proteobacteria	endonuclease activity [GO:0004519]; ribonuclease activity [GO:0004540]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	extrachromosomal circular DNA [GO:0005727]; ribonuclease activity [GO:0004540]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]		extrachromosomal circular DNA [GO:0005727]	endonuclease activity [GO:0004519]; ribonuclease activity [GO:0004540]	ribonuclease activity [GO:0004540]
d2a8na1_d2b1ga2__1		Metazoa	Proteobacteria	Chordata	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	tRNA wobble adenosine to inosine editing [GO:0002100]	'de novo' IMP biosynthetic process [GO:0006189]		cytosol [GO:0005829]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d2a8nb__d2b3jb___1			Proteobacteria	Firmicutes	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	tRNA wobble adenosine to inosine editing [GO:0002100]	tRNA wobble adenosine to inosine editing [GO:0002100]			tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]
d2a8ta__d2g74a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cobalt ion binding [GO:0050897]; dITP diphosphatase activity [GO:0035870]; GTP binding [GO:0005525]; ITP binding [GO:1901641]; m7G(5')pppN diphosphatase activity [GO:0050072]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; mRNA binding [GO:0003729]; nucleotide phosphatase activity, acting on free nucleotides [GO:0098519]; protein homodimerization activity [GO:0042803]; snoRNA binding [GO:0030515]; XTP binding [GO:1901640]; adenosine to inosine editing [GO:0006382]; dITP catabolic process [GO:0035863]; IDP catabolic process [GO:0046709]; mRNA catabolic process [GO:0006402]; negative regulation of rRNA processing [GO:2000233]; positive regulation of cell cycle process [GO:0090068]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of double-strand break repair [GO:2000781]; snoRNA catabolic process [GO:0016077]; XDP catabolic process [GO:1901639]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	adenosine to inosine editing [GO:0006382]; dITP catabolic process [GO:0035863]; IDP catabolic process [GO:0046709]; mRNA catabolic process [GO:0006402]; negative regulation of rRNA processing [GO:2000233]; positive regulation of cell cycle process [GO:0090068]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of double-strand break repair [GO:2000781]; snoRNA catabolic process [GO:0016077]; XDP catabolic process [GO:1901639]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	cobalt ion binding [GO:0050897]; dITP diphosphatase activity [GO:0035870]; GTP binding [GO:0005525]; ITP binding [GO:1901641]; m7G(5')pppN diphosphatase activity [GO:0050072]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; mRNA binding [GO:0003729]; nucleotide phosphatase activity, acting on free nucleotides [GO:0098519]; protein homodimerization activity [GO:0042803]; snoRNA binding [GO:0030515]; XTP binding [GO:1901640]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]
d2a92a1_d4zvvd1__1		Metazoa	Apicomplexa	Chordata	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2a92a2_d2hjri2__1			Apicomplexa	Apicomplexa	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]			L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d2a92b1_d4q9ng___1			Apicomplexa		L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]				L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	
d2a92b2_d2hjrh2__1			Apicomplexa	Apicomplexa	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]			L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d2a92c1_d2tmge1__1			Apicomplexa	Thermotogae	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cellular amino acid metabolic process [GO:0006520]			L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d2a92d1_d5jyda___1			Apicomplexa	Proteobacteria	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]				L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2a94a2_d4uumb2__1			Apicomplexa		L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]			L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]; nucleotide binding [GO:0000166]
d2a99a1_d1ogpd1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]
d2a99a1_d4yeep1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]	enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]
d2a9ba2_d3hbqa1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]
d2a9fb1_d2eggb1__1			Firmicutes	Firmicutes	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]			malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d2a9ia__d1cy5a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]; ATP binding [GO:0005524]; interleukin-1 receptor binding [GO:0005149]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of smooth muscle cell proliferation [GO:0048661]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of smooth muscle cell proliferation [GO:0048661]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; interleukin-1 receptor binding [GO:0005149]; magnesium ion binding [GO:0000287]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d2a9oa__d4uhjb1__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; cell adhesion [GO:0007155]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell-substrate adhesion [GO:0010810]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cell adhesion [GO:0007155]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell-substrate adhesion [GO:0010810]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]	DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2aa1b1_d5vnua___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2aa1c__d2zlxa___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	hemoglobin complex [GO:0005833]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2aa1d__d1ewab___1	Metazoa	Metazoa	Chordata	Annelida	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d2aa3b1_d4wlub1__1		Metazoa	Apicomplexa	Chordata	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d2aa3c2_d1uxib2__1			Apicomplexa	Chloroflexi	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	L-malate dehydrogenase activity [GO:0030060]
d2aa4b1_d1bo5o2__1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; N-acylmannosamine kinase activity [GO:0009384]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	cellular response to DNA damage stimulus [GO:0006974]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]		cytosol [GO:0005829]	ATP binding [GO:0005524]; N-acylmannosamine kinase activity [GO:0009384]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d2aa4b2_d5mvva2__1		Metazoa	Proteobacteria	Chordata	ATP binding [GO:0005524]; N-acylmannosamine kinase activity [GO:0009384]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; actin polymerization or depolymerization [GO:0008154]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; barbed-end actin filament capping [GO:0051016]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]; vesicle-mediated transport [GO:0016192]	cellular response to DNA damage stimulus [GO:0006974]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; actin polymerization or depolymerization [GO:0008154]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; barbed-end actin filament capping [GO:0051016]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]; vesicle-mediated transport [GO:0016192]		actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]	ATP binding [GO:0005524]; N-acylmannosamine kinase activity [GO:0009384]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d2aaaa1_d2zica2__1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	cytoplasm [GO:0005737]; glucan 1,6-alpha-glucosidase activity [GO:0043896]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	glucan 1,6-alpha-glucosidase activity [GO:0043896]
d2aaaa2_d1isyb2__1	Fungi		Ascomycota	Actinobacteria	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	carbohydrate catabolic process [GO:0016052]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	endo-1,4-beta-xylanase activity [GO:0031176]
d2aabh1_d5w1ws1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2aadb__d3wr2c___1	Fungi	Fungi	Ascomycota	Basidiomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]		endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d2aaia__d4kl4a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2aaib2_d1isza1__1	Viridiplantae		Streptophyta	Actinobacteria	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	polysaccharide catabolic process [GO:0000272]	endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	endo-1,4-beta-xylanase activity [GO:0031176]
d2aaja1_d2aagb2__1			Proteobacteria	Proteobacteria								
d2aajb__d3gacb1__1			Proteobacteria	Apicomplexa								
d2aarr1_d2qexs1__1			Deinococcus-Thermus	Euryarchaeota	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2aata__d4lnla___1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	
d2aava1_d2wlka2__1	Metazoa		Chordata	Proteobacteria	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; regulation of ion transmembrane transport [GO:0034765]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	regulation of ion transmembrane transport [GO:0034765]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	integral component of membrane [GO:0016021]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]
d2aawc2_d1zyeg1__1		Metazoa	Apicomplexa	Chordata	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	glutathione transferase activity [GO:0004364]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d2aaze__d1ju6d___1	Fungi	Metazoa	Basidiomycota	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	thymidylate synthase activity [GO:0004799]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d2aazh__d1axwa___1	Fungi		Basidiomycota	Proteobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	thymidylate synthase activity [GO:0004799]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]
d2aazh__d4iqbb___1	Fungi	Metazoa	Basidiomycota	Nematoda (roundworms)	cytosol [GO:0005829]; mitochondrion [GO:0005739]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d2ab6a1_d4zb6a2__1	Metazoa	Fungi	Chordata	Basidiomycota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]		cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	
d2ab6a2_d2aytb2__1	Metazoa		Chordata	Aquificae	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]		cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	
d2abaa__d5cpla___1			Proteobacteria	Proteobacteria	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2abda__d2wh5a___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]			endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]		fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]
d2abla2_d1a1eb___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]
d2abwb2_d1ggkc1__1			Apicomplexa	Proteobacteria	cytosol [GO:0005829]; glutaminase complex [GO:1903600]; glutaminase activity [GO:0004359]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; glutamine metabolic process [GO:0006541]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; response to singlet oxygen [GO:0000304]; vitamin B6 biosynthetic process [GO:0042819]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	glutamine metabolic process [GO:0006541]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; response to singlet oxygen [GO:0000304]; vitamin B6 biosynthetic process [GO:0042819]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutaminase activity [GO:0004359]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2ac0c__d3wtva___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]
d2ac0d__d1p7hn2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d2ac2a__d1qgoa___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]; anaerobic cobalamin biosynthetic process [GO:0019251]; porphyrin-containing compound biosynthetic process [GO:0006779]	heme biosynthetic process [GO:0006783]	anaerobic cobalamin biosynthetic process [GO:0019251]; porphyrin-containing compound biosynthetic process [GO:0006779]	cytoplasm [GO:0005737]		ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]
d2ac4a__d2qd5a___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	heme biosynthetic process [GO:0006783]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cytoplasm [GO:0005737]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d2acfa1_d5cmsl___1				Proteobacteria	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]; negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]		cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]
d2acfb2_d5lccb1__1				Firmicutes	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	nucleotide binding [GO:0000166]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]		cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	nucleotide binding [GO:0000166]
d2acfc2_d3ejfa___1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of host autophagy [GO:0039520]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; zinc ion binding [GO:0008270]
d2aclh2_d1xpca___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; protein heterodimerization activity [GO:0046982]; retinoid X receptor binding [GO:0046965]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; sterol response element binding [GO:0032810]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; apoptotic cell clearance [GO:0043277]; cell differentiation [GO:0030154]; cellular lipid metabolic process [GO:0044255]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; fatty acid biosynthetic process [GO:0006633]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; multicellular organism development [GO:0007275]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of inflammatory response [GO:0050728]; negative regulation of lipid transport [GO:0032369]; negative regulation of macrophage activation [GO:0043031]; negative regulation of pancreatic juice secretion [GO:0090188]; negative regulation of pinocytosis [GO:0048550]; negative regulation of proteolysis [GO:0045861]; negative regulation of secretion of lysosomal enzymes [GO:0090341]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of lipoprotein lipase activity [GO:0051006]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of nuclear receptor transcription coactivator activity [GO:2000325]; regulation of transcription, DNA-templated [GO:0006355]; response to progesterone [GO:0032570]; sterol homeostasis [GO:0055092]; triglyceride homeostasis [GO:0070328]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transcriptional preinitiation complex [GO:0097550]; transcriptionally active chromatin [GO:0035327]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor activity [GO:0030284]; estrogen receptor binding [GO:0030331]; estrogen response element binding [GO:0034056]; identical protein binding [GO:0042802]; nitric-oxide synthase regulator activity [GO:0030235]; nuclear receptor activity [GO:0004879]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; steroid binding [GO:0005496]; TBP-class protein binding [GO:0017025]; TFIIB-class transcription factor binding [GO:0001093]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; androgen metabolic process [GO:0008209]; antral ovarian follicle growth [GO:0001547]; cellular response to estradiol stimulus [GO:0071392]; cellular response to estrogen stimulus [GO:0071391]; chromatin remodeling [GO:0006338]; epithelial cell development [GO:0002064]; epithelial cell proliferation involved in mammary gland duct elongation [GO:0060750]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; male gonad development [GO:0008584]; mammary gland alveolus development [GO:0060749]; mammary gland branching involved in pregnancy [GO:0060745]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; protein deubiquitination [GO:0016579]; protein localization to chromatin [GO:0071168]; regulation of apoptotic process [GO:0042981]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of inflammatory response [GO:0050727]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; signal transduction [GO:0007165]; stem cell differentiation [GO:0048863]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]; uterus development [GO:0060065]; vagina development [GO:0060068]	apoptotic cell clearance [GO:0043277]; cell differentiation [GO:0030154]; cellular lipid metabolic process [GO:0044255]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; fatty acid biosynthetic process [GO:0006633]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; multicellular organism development [GO:0007275]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of inflammatory response [GO:0050728]; negative regulation of lipid transport [GO:0032369]; negative regulation of macrophage activation [GO:0043031]; negative regulation of pancreatic juice secretion [GO:0090188]; negative regulation of pinocytosis [GO:0048550]; negative regulation of proteolysis [GO:0045861]; negative regulation of secretion of lysosomal enzymes [GO:0090341]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of lipoprotein lipase activity [GO:0051006]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of nuclear receptor transcription coactivator activity [GO:2000325]; regulation of transcription, DNA-templated [GO:0006355]; response to progesterone [GO:0032570]; sterol homeostasis [GO:0055092]; triglyceride homeostasis [GO:0070328]	androgen metabolic process [GO:0008209]; antral ovarian follicle growth [GO:0001547]; cellular response to estradiol stimulus [GO:0071392]; cellular response to estrogen stimulus [GO:0071391]; chromatin remodeling [GO:0006338]; epithelial cell development [GO:0002064]; epithelial cell proliferation involved in mammary gland duct elongation [GO:0060750]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; male gonad development [GO:0008584]; mammary gland alveolus development [GO:0060749]; mammary gland branching involved in pregnancy [GO:0060745]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; protein deubiquitination [GO:0016579]; protein localization to chromatin [GO:0071168]; regulation of apoptotic process [GO:0042981]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of inflammatory response [GO:0050727]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; signal transduction [GO:0007165]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; uterus development [GO:0060065]; vagina development [GO:0060068]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transcriptionally active chromatin [GO:0035327]; transcriptional preinitiation complex [GO:0097550]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; protein heterodimerization activity [GO:0046982]; retinoid X receptor binding [GO:0046965]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; sterol response element binding [GO:0032810]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor activity [GO:0030284]; estrogen receptor binding [GO:0030331]; estrogen response element binding [GO:0034056]; identical protein binding [GO:0042802]; nitric-oxide synthase regulator activity [GO:0030235]; nuclear receptor activity [GO:0004879]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; steroid binding [GO:0005496]; TBP-class protein binding [GO:0017025]; TFIIB-class transcription factor binding [GO:0001093]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2aczb2_d1b9ra___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2ad6a__d1h4ic___1			Proteobacteria	Proteobacteria	plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol oxidation [GO:0015946]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol metabolic process [GO:0015945]	methanol oxidation [GO:0015946]	methanol metabolic process [GO:0015945]	plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]
d2ad7a__d1eeea___1			Proteobacteria		plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol oxidation [GO:0015946]		methanol oxidation [GO:0015946]		plasma membrane [GO:0005886]		2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]	
d2ad8b__d4tqoi___1			Proteobacteria	Proteobacteria	plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol oxidation [GO:0015946]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; alcohol dehydrogenase (acceptor) activity [GO:0018468]; calcium ion binding [GO:0005509]; methanol oxidation [GO:0015946]; oxidation-reduction process [GO:0055114]	methanol oxidation [GO:0015946]	methanol oxidation [GO:0015946]; oxidation-reduction process [GO:0055114]	plasma membrane [GO:0005886]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]	alcohol dehydrogenase (acceptor) activity [GO:0018468]; calcium ion binding [GO:0005509]
d2ad8c__d4tqoh___1			Proteobacteria	Proteobacteria	plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol oxidation [GO:0015946]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; alcohol dehydrogenase (acceptor) activity [GO:0018468]; calcium ion binding [GO:0005509]; methanol oxidation [GO:0015946]; oxidation-reduction process [GO:0055114]	methanol oxidation [GO:0015946]	methanol oxidation [GO:0015946]; oxidation-reduction process [GO:0055114]	plasma membrane [GO:0005886]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]	alcohol dehydrogenase (acceptor) activity [GO:0018468]; calcium ion binding [GO:0005509]
d2ad9a1_d3hi9b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]	poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]	AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d2adaa__d4ergb___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; in utero embryonic development [GO:0001701]; inosine biosynthetic process [GO:0046103]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]		cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]		adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2adca1_d5oo6t___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]	poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]	mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]
d2adfa__d1ty6b6__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2adia1_d5c6wh2__1		Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d2adja1_d4q0xl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	metal ion binding [GO:0046872]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d2adja2_d4iiqc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2adma2_d2ibsa2__1			Deinococcus-Thermus	Deinococcus-Thermus	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]
d2adpa2_d1b06c2__1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2adqb1_d3h1sa1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2ae7a__d1hm9b2__1	Metazoa		Chordata	Firmicutes	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	cytoplasm [GO:0005737]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d2aeba__d1p8sb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d2aeja1_d4ijva___1		Metazoa	Euryarchaeota	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	potassium ion transport [GO:0006813]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d2aeka__d5il3a2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d2aekb__d5ik0a2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d2aela__d4kwda___1	Fungi	Fungi	Ascomycota	Ascomycota	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]	sesquiterpenoid biosynthetic process [GO:0016106]				metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]
d2aenc__d1hdka___1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; carbohydrate binding [GO:0030246]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; identical protein binding [GO:0042802]; multicellular organism development [GO:0007275]; regulation of activated T cell proliferation [GO:0046006]; regulation of T cell anergy [GO:0002667]; regulation of T cell cytokine production [GO:0002724]; T cell apoptotic process [GO:0070231]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	multicellular organism development [GO:0007275]; regulation of activated T cell proliferation [GO:0046006]; regulation of T cell anergy [GO:0002667]; regulation of T cell cytokine production [GO:0002724]; T cell apoptotic process [GO:0070231]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]		carbohydrate binding [GO:0030246]; cysteine-type endopeptidase activity involved in apoptotic process [GO:0097153]; identical protein binding [GO:0042802]
d2aend__d1gsla___1		Viridiplantae		Streptophyta	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]		host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2aene__d2exjc1__1				Firmicutes	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2aene__d5gzga___1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]		carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d2aenf__d1n47c___1		Viridiplantae		Streptophyta	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]		host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2aenh__d1qmo.1__1		Viridiplantae		Streptophyta	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	protein storage vacuole lumen [GO:0034495]; carbohydrate binding [GO:0030246]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]		host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	protein storage vacuole lumen [GO:0034495]		carbohydrate binding [GO:0030246]
d2aeqa__d4qn7a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2aeql__d5th9l2__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d2aeql__d5vl3f1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; carbohydrate binding [GO:0030246]; CD4 receptor binding [GO:0042609]; IgM binding [GO:0001791]; protein phosphatase binding [GO:0019903]; sialic acid binding [GO:0033691]; signaling receptor binding [GO:0005102]; B cell activation [GO:0042113]; cell adhesion [GO:0007155]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of immunoglobulin secretion [GO:0051025]; regulation of B cell proliferation [GO:0030888]; regulation of endocytosis [GO:0030100]; regulation of immune response [GO:0050776]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	B cell activation [GO:0042113]; cell adhesion [GO:0007155]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of immunoglobulin secretion [GO:0051025]; regulation of B cell proliferation [GO:0030888]; regulation of endocytosis [GO:0030100]; regulation of immune response [GO:0050776]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; CD4 receptor binding [GO:0042609]; IgM binding [GO:0001791]; protein phosphatase binding [GO:0019903]; sialic acid binding [GO:0033691]; signaling receptor binding [GO:0005102]
d2aerh__d1svpb___1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]
d2aesc__d3d98a1__1	Metazoa		Chordata	Actinobacteria	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]; adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	cytoplasm [GO:0005737]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]
d2aeta__d1kiyb___1	Fungi	Fungi	Ascomycota	Ascomycota	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]			metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]
d2af8a__d4pxhf1__1			Actinobacteria	Actinobacteria	antibiotic biosynthetic process [GO:0017000]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	antibiotic biosynthetic process [GO:0017000]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2afha__d1n2cd___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2afhe__d1yraa2__1			Proteobacteria	Euryarchaeota	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]	nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]
d2afid__d1mioa___1			Proteobacteria	Firmicutes	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2afii__d3zk7a___1			Proteobacteria	Firmicutes	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	nitrogen fixation [GO:0009399]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	molybdenum-iron nitrogenase complex [GO:0016612]	plasma membrane [GO:0005886]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	metal ion binding [GO:0046872]
d2afij__d4wesd___1			Proteobacteria	Firmicutes	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2afik__d4wzbb___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2afim__d5usjc1__1		Metazoa	Proteobacteria	Chordata	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]; actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	nitrogen fixation [GO:0009399]	actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	molybdenum-iron nitrogenase complex [GO:0016612]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]
d2afin__d1bifa1__1		Metazoa	Proteobacteria	Chordata	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]	nitrogen fixation [GO:0009399]	fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]	molybdenum-iron nitrogenase complex [GO:0016612]	cytosol [GO:0005829]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]
d2afio__d2nz8a___1		Metazoa	Proteobacteria	Chordata	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; histone deacetylase binding [GO:0042826]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cell-matrix adhesion [GO:0007160]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	nitrogen fixation [GO:0009399]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	molybdenum-iron nitrogenase complex [GO:0016612]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; histone deacetylase binding [GO:0042826]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]
d2afkc__d3tlkb___1				Proteobacteria		cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; cellular response to DNA damage stimulus [GO:0006974]; ferric-enterobactin import into cell [GO:0015685]		cellular response to DNA damage stimulus [GO:0006974]; ferric-enterobactin import into cell [GO:0015685]		cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]		
d2afke__d1yr7a2__1				Euryarchaeota		GTP binding [GO:0005525]; hydrolase activity [GO:0016787]						GTP binding [GO:0005525]; hydrolase activity [GO:0016787]
d2afkh__d1dafa___1				Proteobacteria		cytosol [GO:0005829]; ATP binding [GO:0005524]; dethiobiotin synthase activity [GO:0004141]; magnesium ion binding [GO:0000287]; biotin biosynthetic process [GO:0009102]		biotin biosynthetic process [GO:0009102]		cytosol [GO:0005829]		ATP binding [GO:0005524]; dethiobiotin synthase activity [GO:0004141]; magnesium ion binding [GO:0000287]
d2afnb1_d3v9ca2__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2afnb2_d4knub2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2afnc2_d4knsc1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2agdc__d3v0ob___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]
d2aggx__d2bdhd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2agix__d1cu1b1__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2agix__d2fs8b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2agjh2_d1ru9l1__1	Metazoa	Metazoa	Chordata	Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2agjl1_d1ct8a1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2agjl1_d4zfob1__1	Metazoa	Metazoa	Chordata	Chordata		endomembrane system [GO:0012505]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; lymphocyte homeostasis [GO:0002260]; multicellular organism development [GO:0007275]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		adaptive immune response [GO:0002250]; lymphocyte homeostasis [GO:0002260]; multicellular organism development [GO:0007275]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		endomembrane system [GO:0012505]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		signaling receptor activity [GO:0038023]
d2agjl2_d2fx8o1__1	Metazoa		Chordata			host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d2agsa2_d3sala___1				Negarnaviricota	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2ah2a1_d5duxc___1		Metazoa		Chordata	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]	pathogenesis [GO:0009405]	cell adhesion [GO:0007155]		collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	exo-alpha-sialidase activity [GO:0004308]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2ah7x2_d5f7ga___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	vasodilation [GO:0042311]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d2ahbb1_d4ryba2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2ahid__d1le9e2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2ahjd__d4fm4d___1			Actinobacteria	Proteobacteria	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d2ahka1_d4p6ra___1			Actinobacteria	Firmicutes	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2ahmd2_d2ahma1__1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2ahmd2_d3ub0f1__1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2ahsa__d4bpca2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; angiogenesis [GO:0001525]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; phosphate-containing compound metabolic process [GO:0006796]; protein dephosphorylation [GO:0006470]	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]	angiogenesis [GO:0001525]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; phosphate-containing compound metabolic process [GO:0006796]; protein dephosphorylation [GO:0006470]	cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]
d2ahvb2_d4eu3b1__1			Proteobacteria	Proteobacteria	acetate CoA-transferase activity [GO:0008775]; ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]	acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]			acetate CoA-transferase activity [GO:0008775]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d2ahvd2_d3oxoe2__1		Metazoa	Proteobacteria	Chordata	acetate CoA-transferase activity [GO:0008775]; ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]		mitochondrion [GO:0005739]	acetate CoA-transferase activity [GO:0008775]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]
d2ahwb2_d3cdka___1			Proteobacteria	Firmicutes	acetate CoA-transferase activity [GO:0008775]; ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]	3-oxoacid CoA-transferase activity [GO:0008260]	ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]				acetate CoA-transferase activity [GO:0008775]	3-oxoacid CoA-transferase activity [GO:0008260]
d2ahwd2_d1vb5a___1			Proteobacteria	Euryarchaeota	acetate CoA-transferase activity [GO:0008775]; ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]	translation initiation factor activity [GO:0003743]	ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]				acetate CoA-transferase activity [GO:0008775]	translation initiation factor activity [GO:0003743]
d2ai0h1_d1bbjl2__1	Metazoa	Metazoa	Chordata	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ai0h1_d3l5wa1__1	Metazoa	Metazoa	Chordata	Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]
d2ai0l1_d5m2mh1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]		cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d2ai0l2_d4gkzb1__1	Metazoa		Chordata									
d2ai0o2_d1nd0a1__1	Metazoa	Metazoa	Chordata	Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d2ai8c__d4dr9b___1			Proteobacteria	Cyanobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	translation [GO:0006412]	cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d2aibb__d1lria___1					extracellular region [GO:0005576]; steroid binding [GO:0005496]; lipid transport [GO:0006869]; modulation by symbiont of host defense-related programmed cell death [GO:0034053]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; modulation by symbiont of host defense-related programmed cell death [GO:0034053]; pathogenesis [GO:0009405]	lipid transport [GO:0006869]; modulation by symbiont of host defense-related programmed cell death [GO:0034053]; pathogenesis [GO:0009405]	modulation by symbiont of host defense-related programmed cell death [GO:0034053]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	steroid binding [GO:0005496]	
d2aidb__d5p13a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2aima__d1ggua4__1		Metazoa		Chordata	cysteine-type endopeptidase activity [GO:0004197]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]		blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	cysteine-type endopeptidase activity [GO:0004197]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d2aioa__d3ie1b___1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	rRNA processing [GO:0006364]	periplasmic space [GO:0042597]	cytoplasm [GO:0005737]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2aioa__d5hh4c___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2aipa__d1c2la___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2aiqa__d4dcda1__1	Metazoa		Chordata		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2aira1_d3e2pb2__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d2aira2_d2at2c1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d2aixa__d5ns9a1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2aj3c2_d4rfef1__1												
d2aj8a2_d5alya2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2aj8b2_d1xfdd2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]; potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]
d2aj8d1_d2g63b1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2aj9a1_d3kzuc1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d2aj9a2_d4n44b1__1			Actinobacteria		cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	
d2aj9b1_d2vu2d1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2aj9b2_d5ld8a2__1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]
d2ajba2_d3cccc2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2ajbd2_d5alqa2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2ajcb2_d5fkjd___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]; acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]
d2ajcc2_d3wk9a2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2ajdb1_d3kwjb1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2ajdb2_d3d2aa___1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	extracellular region [GO:0005576]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d2ajdc1_d3opmd1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2ajli2_d5xg0c1__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; carboxylic ester hydrolase activity [GO:0052689]; cellular response to organic substance [GO:0071310]; xenobiotic catabolic process [GO:0042178]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellular response to organic substance [GO:0071310]; xenobiotic catabolic process [GO:0042178]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	carboxylic ester hydrolase activity [GO:0052689]
d2ajqa1_d2guia___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; DNA replication proofreading [GO:0045004]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	DNA replication proofreading [GO:0045004]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]
d2ajqb__d2vl3c___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]
d2ajqf1_d3tana1__1			Proteobacteria		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	
d2ajsl1_d5n2dc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2ajta2_d3a9sa1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	L-fucose catabolic process [GO:0042355]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]
d2ajtc1_d1fuib1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytosol [GO:0005829]; arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	cytosol [GO:0005829]	cytosol [GO:0005829]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]	arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]
d2ajtc2_d3a9rc1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	L-fucose catabolic process [GO:0042355]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]
d2ajul1_d1de4e___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ajul2_d3cfkf1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ajvl1_d2p4ab___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d2ajxl1_d1kcsl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ajyl1_d4huua2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ajza1_d3cxhk___1	Metazoa	Fungi	Chordata	Ascomycota	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2ajza2_d4ynyb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2ajza2_d5if0l2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2ajzl1_d1zvya1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2ajzl1_d2iane1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ajzl2_d3juye2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2ak1l1_d4hlzj1__1	Metazoa		Chordata	Negarnaviricota	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	host cell surface receptor binding [GO:0046789]
d2ak1l2_d2esve1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ak4f1_d1cvsd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]
d2ak4f2_d5u6qc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ak4i1_d1zlvm1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2ak4j1_d2iamd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ak4j2_d3ta3c1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ak4k1_d5ijvc2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2ak4k2_d1agda2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ak4n1_d5ovwi___1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; cobalamin binding [GO:0031419]; cobalamin transport [GO:0015889]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cobalamin transport [GO:0015889]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cobalamin binding [GO:0031419]
d2ak4q2_d5iuea1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ak4r__d1jv5a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d2ak4t2_d1l7sl3__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2ak4u2_d4zg1d1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2akab1_d1g7ca3__1	Metazoa	Fungi	Chordata	Ascomycota	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendritic spine [GO:0043197]; dendritic spine head [GO:0044327]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane coat [GO:0030117]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic endocytic zone membrane [GO:0098844]; postsynaptic membrane [GO:0045211]; presynaptic endocytic zone membrane [GO:0098835]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; varicosity [GO:0043196]; D2 dopamine receptor binding [GO:0031749]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; SH3 domain binding [GO:0017124]; endosome organization [GO:0007032]; G protein-coupled receptor internalization [GO:0002031]; mitochondrial fission [GO:0000266]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of synaptic vesicle recycling [GO:1903423]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synapse structure or activity [GO:0050803]; regulation of synaptic vesicle endocytosis [GO:1900242]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; toxin transport [GO:1901998]	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	endosome organization [GO:0007032]; G protein-coupled receptor internalization [GO:0002031]; mitochondrial fission [GO:0000266]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of synaptic vesicle recycling [GO:1903423]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synapse structure or activity [GO:0050803]; regulation of synaptic vesicle endocytosis [GO:1900242]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; toxin transport [GO:1901998]	maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendritic spine [GO:0043197]; dendritic spine head [GO:0044327]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane coat [GO:0030117]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic endocytic zone membrane [GO:0098844]; postsynaptic membrane [GO:0045211]; presynaptic endocytic zone membrane [GO:0098835]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; varicosity [GO:0043196]	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]	D2 dopamine receptor binding [GO:0031749]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; SH3 domain binding [GO:0017124]	guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]
d2akja1_d2akja2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate assimilation [GO:0042128]	chloroplast [GO:0009507]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate assimilation [GO:0042128]	nitrate assimilation [GO:0042128]	nitrate assimilation [GO:0042128]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2akja1_d3vkqa3__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate assimilation [GO:0042128]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	nitrate assimilation [GO:0042128]		chloroplast [GO:0009507]		4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2akja3_d3b0hb4__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate assimilation [GO:0042128]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	nitrate assimilation [GO:0042128]		chloroplast [GO:0009507]		4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2akmb1_d1l8pa1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2akqc__d1vyga___1	Metazoa	Metazoa	Chordata	Platyhelminthes	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cytoplasm [GO:0005737]; lipid binding [GO:0008289]			extracellular region [GO:0005576]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	lipid binding [GO:0008289]
d2akqd__d3stka1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]		cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]
d2akrc2_d1kj3i2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2akza1_d1e9ia1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2akzb2_d2mnra2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d2al4a__d3r6ua___1	Metazoa		Chordata	Firmicutes	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; amino acid transport [GO:0006865]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	amino acid transport [GO:0006865]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	transmembrane transporter activity [GO:0022857]
d2al6a1_d4zrja2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]; actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]	actin binding [GO:0003779]
d2al6b2_d5nbfa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]; actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; synapse [GO:0045202]; actin binding [GO:0003779]; profilin binding [GO:0005522]; SH3 domain binding [GO:0017124]; WW domain binding [GO:0050699]; actin polymerization or depolymerization [GO:0008154]; actin polymerization-dependent cell motility [GO:0070358]; axon guidance [GO:0007411]	actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	actin polymerization-dependent cell motility [GO:0070358]; actin polymerization or depolymerization [GO:0008154]; axon guidance [GO:0007411]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]	cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; synapse [GO:0045202]	ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]	actin binding [GO:0003779]; profilin binding [GO:0005522]; SH3 domain binding [GO:0017124]; WW domain binding [GO:0050699]
d2al6b3_d2emsa3__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]; actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d2alea1_d1q7yh___1	Fungi		Ascomycota	Euryarchaeota	box C/D snoRNP complex [GO:0031428]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511]; U4 snRNA binding [GO:0030621]; maturation of LSU-rRNA [GO:0000470]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of RNA binding [GO:1905216]; rRNA 2'-O-methylation [GO:0000451]; rRNA methylation [GO:0031167]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	maturation of LSU-rRNA [GO:0000470]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of RNA binding [GO:1905216]; rRNA 2'-O-methylation [GO:0000451]; rRNA methylation [GO:0031167]	translation [GO:0006412]	box C/D snoRNP complex [GO:0031428]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; small-subunit processome [GO:0032040]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]	ribosome [GO:0005840]	RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511]; U4 snRNA binding [GO:0030621]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2algb__d1gh1a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid transport [GO:0006869]	lipid transport [GO:0006869]			lipid binding [GO:0008289]	lipid binding [GO:0008289]
d2algb__d1siya___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid binding [GO:0008289]; defense response to fungus [GO:0050832]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]; lipid transport [GO:0006869]	lipid transport [GO:0006869]	defense response to fungus [GO:0050832]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]; lipid transport [GO:0006869]			lipid binding [GO:0008289]	lipid binding [GO:0008289]
d2allx__d3d95b___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	vasodilation [GO:0042311]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	extracellular region [GO:0005576]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d2alma1_d1ek4a1__1			Firmicutes	Proteobacteria	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2amca__d6aqha2__1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	phenylalanyl-tRNA aminoacylation [GO:0006432]	lysyl-tRNA aminoacylation [GO:0006430]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d2amfa1_d5bsee2__1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]; L-proline biosynthetic process [GO:0055129]	cell wall [GO:0005618]; nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]; L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]	L-proline biosynthetic process [GO:0055129]	L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]	cell wall [GO:0005618]	nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]	nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d2amfa2_d1jaxb___1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]; L-proline biosynthetic process [GO:0055129]	8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity [GO:0102261]; coenzyme F420 binding [GO:0070967]; NADP binding [GO:0050661]; reduced coenzyme F420:NADP+ oxidoreductase activity [GO:0052808]; NADPH regeneration [GO:0006740]	L-proline biosynthetic process [GO:0055129]	NADPH regeneration [GO:0006740]	cytoplasm [GO:0005737]		nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]	8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity [GO:0102261]; coenzyme F420 binding [GO:0070967]; NADP binding [GO:0050661]; reduced coenzyme F420:NADP+ oxidoreductase activity [GO:0052808]
d2amfc2_d1iy8f___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]; L-proline biosynthetic process [GO:0055129]	oxidoreductase activity [GO:0016491]	L-proline biosynthetic process [GO:0055129]		cytoplasm [GO:0005737]		nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]	oxidoreductase activity [GO:0016491]
d2ammx__d1exsa___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	extracellular region [GO:0005576]; retinol binding [GO:0019841]	vasodilation [GO:0042311]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	retinol binding [GO:0019841]
d2ampa__d4mtba___1		Metazoa		Chordata	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2ampb__d4gawb___1		Metazoa		Chordata	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasm [GO:0005737]; membrane [GO:0016020]; serine-type endopeptidase activity [GO:0004252]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]
d2ampb__d5dp7a1__1					host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2amqa__d2qaaa___1				Actinobacteria	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]
d2amtc__d3ieqa___1			Proteobacteria	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d2amua1_d4bffj___1			Thermotogae	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]					iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d2an3a__d5p9da___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	phenylethanolamine N-methyltransferase activity [GO:0004603]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d2an4a2_d4y30a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; histone methyltransferase activity [GO:0042054]; histone methyltransferase activity (H2A-R3 specific) [GO:0070612]; histone methyltransferase activity (H3-R2 specific) [GO:0070611]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; histone-arginine N-methyltransferase activity [GO:0008469]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; base-excision repair [GO:0006284]; cellular senescence [GO:0090398]; histone H3-R2 methylation [GO:0034970]; histone methylation [GO:0016571]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; viral process [GO:0016032]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	base-excision repair [GO:0006284]; cellular senescence [GO:0090398]; histone H3-R2 methylation [GO:0034970]; histone methylation [GO:0016571]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	phenylethanolamine N-methyltransferase activity [GO:0004603]	chromatin binding [GO:0003682]; histone-arginine N-methyltransferase activity [GO:0008469]; histone binding [GO:0042393]; histone methyltransferase activity [GO:0042054]; histone methyltransferase activity (H2A-R3 specific) [GO:0070612]; histone methyltransferase activity (H3-R2 specific) [GO:0070611]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]
d2an6b1_d1ca4b1__1	Metazoa	Metazoa	Chordata	Chordata	beta-catenin destruction complex [GO:0030877]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; SCF ubiquitin ligase complex [GO:0019005]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; post-embryonic development [GO:0009791]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]; CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; post-embryonic development [GO:0009791]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein-containing complex assembly [GO:0034622]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	beta-catenin destruction complex [GO:0030877]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; SCF ubiquitin ligase complex [GO:0019005]	CD40 receptor complex [GO:0035631]; cell cortex [GO:0005938]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; IRE1-TRAF2-ASK1 complex [GO:1990604]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; ubiquitin ligase complex [GO:0000151]; vesicle membrane [GO:0012506]	disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	CD40 receptor binding [GO:0005174]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; sphingolipid binding [GO:0046625]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d2anec__d1ze1a1__1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; ATP-dependent peptidase activity [GO:0004176]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; peptidase activity [GO:0008233]; sequence-specific DNA binding [GO:0043565]; serine-type endopeptidase activity [GO:0004252]; cellular response to heat [GO:0034605]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to X-ray [GO:0010165]	mitochondrion [GO:0005739]; pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]; mRNA pseudouridine synthesis [GO:1990481]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	cellular response to heat [GO:0034605]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to X-ray [GO:0010165]	mRNA pseudouridine synthesis [GO:1990481]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrion [GO:0005739]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; ATP-dependent peptidase activity [GO:0004176]; DNA binding [GO:0003677]; peptidase activity [GO:0008233]; sequence-specific DNA binding [GO:0043565]; serine-type endopeptidase activity [GO:0004252]	pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]
d2aneg__d1g8ga1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; ATP-dependent peptidase activity [GO:0004176]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; peptidase activity [GO:0008233]; sequence-specific DNA binding [GO:0043565]; serine-type endopeptidase activity [GO:0004252]; cellular response to heat [GO:0034605]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to X-ray [GO:0010165]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	cellular response to heat [GO:0034605]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to X-ray [GO:0010165]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; ATP-dependent peptidase activity [GO:0004176]; DNA binding [GO:0003677]; peptidase activity [GO:0008233]; sequence-specific DNA binding [GO:0043565]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d2ania__d4gamb___1			Chlamydiae	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	ribonucleoside-diphosphate reductase complex [GO:0005971]		metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2ansa__d1bsqa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	extracellular region [GO:0005576]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]
d2ao2c__d5go2c___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; chorismate mutase activity [GO:0004106]; chorismate metabolic process [GO:0046417]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	chorismate metabolic process [GO:0046417]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	extracellular region [GO:0005576]		chorismate mutase activity [GO:0004106]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; chorismate mutase activity [GO:0004106]
d2aobc__d1o4ja___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]
d2aoca__d5p8la___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2aoda__d4y4ta___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2aoea__d1npab___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2aoeb__d4y4aa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2aogb__d5p6ma___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2aoja__d4y3ya___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2aojb__d1htea___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2aoxa__d1jqeb___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; histamine N-methyltransferase activity [GO:0046539]; brain development [GO:0007420]; histamine catabolic process [GO:0001695]; histidine catabolic process [GO:0006548]; hyperosmotic response [GO:0006972]; methylation [GO:0032259]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to amine [GO:0014075]; response to cocaine [GO:0042220]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to interleukin-1 [GO:0070555]; response to tumor cell [GO:0002347]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; histamine N-methyltransferase activity [GO:0046539]; brain development [GO:0007420]; histamine catabolic process [GO:0001695]; histidine catabolic process [GO:0006548]; hyperosmotic response [GO:0006972]; methylation [GO:0032259]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to amine [GO:0014075]; response to cocaine [GO:0042220]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to interleukin-1 [GO:0070555]; response to tumor cell [GO:0002347]	brain development [GO:0007420]; histamine catabolic process [GO:0001695]; histidine catabolic process [GO:0006548]; hyperosmotic response [GO:0006972]; methylation [GO:0032259]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to amine [GO:0014075]; response to cocaine [GO:0042220]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to interleukin-1 [GO:0070555]; response to tumor cell [GO:0002347]	brain development [GO:0007420]; histamine catabolic process [GO:0001695]; histidine catabolic process [GO:0006548]; hyperosmotic response [GO:0006972]; methylation [GO:0032259]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to amine [GO:0014075]; response to cocaine [GO:0042220]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to interleukin-1 [GO:0070555]; response to tumor cell [GO:0002347]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]	histamine N-methyltransferase activity [GO:0046539]	histamine N-methyltransferase activity [GO:0046539]
d2ap1a1_d1woqb2__1			Proteobacteria	Actinobacteria	ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]; zinc ion binding [GO:0008270]; N-acetylglucosamine metabolic process [GO:0006044]; peptidoglycan turnover [GO:0009254]	kinase activity [GO:0016301]	N-acetylglucosamine metabolic process [GO:0006044]; peptidoglycan turnover [GO:0009254]				ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]; zinc ion binding [GO:0008270]	kinase activity [GO:0016301]
d2ap2d__d3kyme1__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; ATPase-coupled xenobiotic transmembrane transporter activity [GO:0008559]; ceramide floppase activity [GO:0099038]; efflux transmembrane transporter activity [GO:0015562]; floppase activity [GO:0140328]; phosphatidylcholine floppase activity [GO:0090554]; phosphatidylethanolamine flippase activity [GO:0090555]; xenobiotic transmembrane transporter activity [GO:0042910]; phospholipid translocation [GO:0045332]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transport across blood-brain barrier [GO:1990962]		phospholipid translocation [GO:0045332]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transport across blood-brain barrier [GO:1990962]		apical plasma membrane [GO:0016324]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]		ATPase activity, coupled [GO:0042623]; ATPase-coupled xenobiotic transmembrane transporter activity [GO:0008559]; ATP binding [GO:0005524]; ceramide floppase activity [GO:0099038]; efflux transmembrane transporter activity [GO:0015562]; floppase activity [GO:0140328]; phosphatidylcholine floppase activity [GO:0090554]; phosphatidylethanolamine flippase activity [GO:0090555]; xenobiotic transmembrane transporter activity [GO:0042910]	
d2apsa__d1kmga___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	periplasmic space [GO:0042597]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d2apta__d5vpgc2__1	Metazoa	Metazoa	Chordata	Arthropoda	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	cysteine-type peptidase activity [GO:0008234]; metal ion binding [GO:0046872]	adaptive immune response [GO:0002250]		T cell receptor complex [GO:0042101]			cysteine-type peptidase activity [GO:0008234]; metal ion binding [GO:0046872]
d2aq0b__d1z00a1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome, telomeric region [GO:0000781]; ERCC4-ERCC1 complex [GO:0070522]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 1 complex [GO:0000110]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; damaged DNA binding [GO:0003684]; endodeoxyribonuclease activity [GO:0004520]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; single-stranded DNA binding [GO:0003697]; single-stranded DNA endodeoxyribonuclease activity [GO:0000014]; TFIID-class transcription factor complex binding [GO:0001094]; cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; global genome nucleotide-excision repair [GO:0070911]; interstrand cross-link repair [GO:0036297]; negative regulation of double-stranded telomeric DNA binding [GO:1905768]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance [GO:0032205]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of autophagy [GO:0010506]; resolution of meiotic recombination intermediates [GO:0000712]; response to UV [GO:0009411]; telomere maintenance [GO:0000723]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650]	chromosome, telomeric region [GO:0000781]; ERCC4-ERCC1 complex [GO:0070522]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 1 complex [GO:0000110]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; damaged DNA binding [GO:0003684]; endodeoxyribonuclease activity [GO:0004520]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; single-stranded DNA binding [GO:0003697]; single-stranded DNA endodeoxyribonuclease activity [GO:0000014]; TFIID-class transcription factor complex binding [GO:0001094]; cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; global genome nucleotide-excision repair [GO:0070911]; interstrand cross-link repair [GO:0036297]; negative regulation of double-stranded telomeric DNA binding [GO:1905768]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance [GO:0032205]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of autophagy [GO:0010506]; resolution of meiotic recombination intermediates [GO:0000712]; response to UV [GO:0009411]; telomere maintenance [GO:0000723]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650]	cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; global genome nucleotide-excision repair [GO:0070911]; interstrand cross-link repair [GO:0036297]; negative regulation of double-stranded telomeric DNA binding [GO:1905768]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance [GO:0032205]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; regulation of autophagy [GO:0010506]; resolution of meiotic recombination intermediates [GO:0000712]; response to UV [GO:0009411]; telomere maintenance [GO:0000723]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650]	cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; global genome nucleotide-excision repair [GO:0070911]; interstrand cross-link repair [GO:0036297]; negative regulation of double-stranded telomeric DNA binding [GO:1905768]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance [GO:0032205]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; regulation of autophagy [GO:0010506]; resolution of meiotic recombination intermediates [GO:0000712]; response to UV [GO:0009411]; telomere maintenance [GO:0000723]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650]	chromosome, telomeric region [GO:0000781]; ERCC4-ERCC1 complex [GO:0070522]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 1 complex [GO:0000110]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]	chromosome, telomeric region [GO:0000781]; ERCC4-ERCC1 complex [GO:0070522]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 1 complex [GO:0000110]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]	damaged DNA binding [GO:0003684]; endodeoxyribonuclease activity [GO:0004520]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; single-stranded DNA binding [GO:0003697]; single-stranded DNA endodeoxyribonuclease activity [GO:0000014]; TFIID-class transcription factor complex binding [GO:0001094]	damaged DNA binding [GO:0003684]; endodeoxyribonuclease activity [GO:0004520]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; single-stranded DNA binding [GO:0003697]; single-stranded DNA endodeoxyribonuclease activity [GO:0000014]; TFIID-class transcription factor complex binding [GO:0001094]
d2aq1a__d1cd1d___1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	T cell receptor complex [GO:0042101]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2aq1c__d4pjhd1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2aq1d1_d1rcvg___1	Metazoa		Chordata	Proteobacteria	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	adaptive immune response [GO:0002250]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	T cell receptor complex [GO:0042101]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]		galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d2aq1e__d5x2pk2__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; G protein-coupled receptor activity [GO:0004930]	adaptive immune response [GO:0002250]		T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		G protein-coupled receptor activity [GO:0004930]
d2aq1f2_d4dxga2__1	Metazoa		Chordata	Firmicutes	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]	pathogenesis [GO:0009405]	T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]		
d2aq1g__d4p57c2__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d2aq1h2_d2z8la2__1	Metazoa		Chordata	Firmicutes	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]	pathogenesis [GO:0009405]	T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]		
d2aq2a1_d3b2uf1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	T cell receptor complex [GO:0042101]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2aq3c__d5l88l2__1	Metazoa		Chordata		T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]		T cell receptor complex [GO:0042101]			
d2aq3d2_d5fkac2__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d2aq3e__d4ij3b1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; platelet alpha granule lumen [GO:0031093]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; FAD binding [GO:0071949]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; extracellular matrix assembly [GO:0085029]; negative regulation of macroautophagy [GO:0016242]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]	adaptive immune response [GO:0002250]	cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; extracellular matrix assembly [GO:0085029]; negative regulation of macroautophagy [GO:0016242]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]	T cell receptor complex [GO:0042101]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; platelet alpha granule lumen [GO:0031093]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		FAD binding [GO:0071949]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide isomerase activity [GO:0003756]
d2aq3f2_d1stea2__1	Metazoa		Chordata	Firmicutes	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	adaptive immune response [GO:0002250]		T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d2aq3h2_d4rgna2__1	Metazoa		Chordata	Firmicutes	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	adaptive immune response [GO:0002250]		T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d2aq6b__d3awhb___1			Actinobacteria	Proteobacteria	coenzyme F420 binding [GO:0070967]; FMN binding [GO:0010181]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; vitamin B6 metabolic process [GO:0042816]	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	vitamin B6 metabolic process [GO:0042816]	oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	coenzyme F420 binding [GO:0070967]; FMN binding [GO:0010181]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]	cofactor binding [GO:0048037]
d2aq7a1_d1ub7b2__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2aq7a2_d2byxd2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2aq7c1_d1zowd1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2aq7d1_d1m3zd2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2aq9a__d5jxxd___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; identical protein binding [GO:0042802]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	lipid A biosynthetic process [GO:0009245]	lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; identical protein binding [GO:0042802]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]
d2aqba2_d4o9cf1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2aqda__d2ccaa1__1	Fungi		Ascomycota	Actinobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]
d2aqia__d2ekqa___1			Actinobacteria	Deinococcus-Thermus	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	nucleotide binding [GO:0000166]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	nucleotide binding [GO:0000166]
d2aqma__d1s4ib___1				Firmicutes		plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]		plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d2aqna__d2yqxe___1			Proteobacteria		periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				periplasmic space [GO:0042597]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	
d2aqqb__d4mcmb___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	periplasmic space [GO:0042597]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d2aqua__d2q3ka___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2aqua__d3fv3b___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2ar5a1_d1kmda___1	Metazoa	Fungi	Chordata	Ascomycota	clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; 1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; phosphatidylinositol 3-kinase activity [GO:0035004]; phosphatidylinositol binding [GO:0035091]; clathrin coat assembly [GO:0048268]; endocytosis [GO:0006897]; epidermal growth factor receptor signaling pathway [GO:0007173]; exocytosis [GO:0006887]; insulin receptor signaling pathway [GO:0008286]; membrane organization [GO:0061024]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; vascular smooth muscle contraction [GO:0014829]	endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; integral component of membrane [GO:0016021]; phagophore assembly site [GO:0000407]; SNARE complex [GO:0031201]; phosphatidylinositol-3-phosphate binding [GO:0032266]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]; autophagosome-lysosome fusion [GO:0061909]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; intracellular protein transport [GO:0006886]; macroautophagy [GO:0016236]; piecemeal microautophagy of the nucleus [GO:0034727]; vacuole fusion, non-autophagic [GO:0042144]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]	clathrin coat assembly [GO:0048268]; endocytosis [GO:0006897]; epidermal growth factor receptor signaling pathway [GO:0007173]; exocytosis [GO:0006887]; insulin receptor signaling pathway [GO:0008286]; membrane organization [GO:0061024]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; vascular smooth muscle contraction [GO:0014829]	autophagosome-lysosome fusion [GO:0061909]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; intracellular protein transport [GO:0006886]; macroautophagy [GO:0016236]; piecemeal microautophagy of the nucleus [GO:0034727]; vacuole fusion, non-autophagic [GO:0042144]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]	clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; integral component of membrane [GO:0016021]; phagophore assembly site [GO:0000407]; SNARE complex [GO:0031201]	1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; phosphatidylinositol 3-kinase activity [GO:0035004]; phosphatidylinositol binding [GO:0035091]	phosphatidylinositol-3-phosphate binding [GO:0032266]; SNAP receptor activity [GO:0005484]; SNARE binding [GO:0000149]
d2ar6a__d1lgne___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d2ar6b__d1les.1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]; carbohydrate mediated signaling [GO:0009756]		carbohydrate mediated signaling [GO:0009756]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]
d2arbb__d1z0hb1__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d2arja1_d4n1ec___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2arja2_d4h0ga2__1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]		cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]		identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]	
d2arja2_d4jzjl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-3 receptor activity [GO:0004912]; cytokine-mediated signaling pathway [GO:0019221]; MAPK cascade [GO:0000165]	cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]	cytokine-mediated signaling pathway [GO:0019221]; MAPK cascade [GO:0000165]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-3 receptor activity [GO:0004912]
d2arjb1_d5h8da1__1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]		cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]		identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]	
d2arjh1_d3stla1__1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]	voltage-gated potassium channel complex [GO:0008076]	identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d2arjl1_d2or7a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ferritin receptor activity [GO:0070287]; iron ion transport [GO:0006826]	cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]	iron ion transport [GO:0006826]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]	ferritin receptor activity [GO:0070287]
d2arjl1_d3gb7b1__1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]	voltage-gated potassium channel complex [GO:0008076]	identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d2arjl2_d3quyd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; defense response to virus [GO:0051607]; positive regulation of calcium-mediated signaling [GO:0050850]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2arob__d4csra___1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	CCAAT-binding factor complex [GO:0016602]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; protein folding [GO:0006457]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]		protein folding [GO:0006457]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleosome [GO:0000786]; nucleus [GO:0005634]	CCAAT-binding factor complex [GO:0016602]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]
d2aroc__d4nftd1__1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nucleosome [GO:0000786]; nucleus [GO:0005634]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; nucleosomal DNA binding [GO:0031492]; protein heterodimerization activity [GO:0046982]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; cellular response to estradiol stimulus [GO:0071392]; chromatin organization [GO:0006325]; positive regulation of transcription by RNA polymerase II [GO:0045944]		cellular response to estradiol stimulus [GO:0071392]; chromatin organization [GO:0006325]; positive regulation of transcription by RNA polymerase II [GO:0045944]	nucleosome [GO:0000786]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; nucleosomal DNA binding [GO:0031492]; protein heterodimerization activity [GO:0046982]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d2aroe__d2arof___1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleosome [GO:0000786]; nucleus [GO:0005634]	nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2arwa__d4lptb1__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; ciliary neurotrophic factor receptor complex [GO:0070110]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor binding [GO:0070119]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; enzyme binding [GO:0019899]; interleukin-6 binding [GO:0019981]; interleukin-6 receptor activity [GO:0004915]; protein homodimerization activity [GO:0042803]; acute-phase response [GO:0006953]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; endocrine pancreas development [GO:0031018]; extrinsic apoptotic signaling pathway [GO:0097191]; hepatic immune response [GO:0002384]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of interleukin-8 production [GO:0032717]; neutrophil mediated immunity [GO:0002446]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of glomerular mesangial cell proliferation [GO:0072126]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to cytokine [GO:0034097]		acute-phase response [GO:0006953]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; endocrine pancreas development [GO:0031018]; extrinsic apoptotic signaling pathway [GO:0097191]; hepatic immune response [GO:0002384]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of interleukin-8 production [GO:0032717]; neutrophil mediated immunity [GO:0002446]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of glomerular mesangial cell proliferation [GO:0072126]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to cytokine [GO:0034097]		apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; ciliary neurotrophic factor receptor complex [GO:0070110]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ciliary neurotrophic factor binding [GO:0070119]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; enzyme binding [GO:0019899]; interleukin-6 binding [GO:0019981]; interleukin-6 receptor activity [GO:0004915]; protein homodimerization activity [GO:0042803]	
d2arxb__d1axya___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d2arza1_d3nfwc___1			Proteobacteria	Actinobacteria	cofactor binding [GO:0048037]	FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]					cofactor binding [GO:0048037]	FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]
d2as3a__d4bm2a___1	Fungi	Fungi	Ascomycota	Basidiomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2as5f__d4i7ha___1	Metazoa		Chordata	Firmicutes	nuclear chromatin [GO:0000790]; androgen receptor binding [GO:0050681]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; camera-type eye development [GO:0043010]; caudate nucleus development [GO:0021757]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; innate vocalization behavior [GO:0098582]; lung alveolus development [GO:0048286]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of mesenchymal cell proliferation [GO:0002053]; post-embryonic development [GO:0009791]; putamen development [GO:0021758]; response to testosterone [GO:0033574]; righting reflex [GO:0060013]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; vocal learning [GO:0042297]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]	camera-type eye development [GO:0043010]; caudate nucleus development [GO:0021757]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; innate vocalization behavior [GO:0098582]; lung alveolus development [GO:0048286]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of mesenchymal cell proliferation [GO:0002053]; post-embryonic development [GO:0009791]; putamen development [GO:0021758]; response to testosterone [GO:0033574]; righting reflex [GO:0060013]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; vocal learning [GO:0042297]		nuclear chromatin [GO:0000790]		androgen receptor binding [GO:0050681]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]
d2as5n1_d3vgda1__1	Metazoa		Chordata	Crenarchaeota	nuclear chromatin [GO:0000790]; androgen receptor binding [GO:0050681]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; camera-type eye development [GO:0043010]; caudate nucleus development [GO:0021757]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; innate vocalization behavior [GO:0098582]; lung alveolus development [GO:0048286]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of mesenchymal cell proliferation [GO:0002053]; post-embryonic development [GO:0009791]; putamen development [GO:0021758]; response to testosterone [GO:0033574]; righting reflex [GO:0060013]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; vocal learning [GO:0042297]	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	camera-type eye development [GO:0043010]; caudate nucleus development [GO:0021757]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; innate vocalization behavior [GO:0098582]; lung alveolus development [GO:0048286]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of mesenchymal cell proliferation [GO:0002053]; post-embryonic development [GO:0009791]; putamen development [GO:0021758]; response to testosterone [GO:0033574]; righting reflex [GO:0060013]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; vocal learning [GO:0042297]	trehalose biosynthetic process [GO:0005992]	nuclear chromatin [GO:0000790]	cytoplasm [GO:0005737]	androgen receptor binding [GO:0050681]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]
d2as6a__d5sx3b2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2as9a1_d2fpzb___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]		proteolysis [GO:0006508]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2asba2_d1k0rb3__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]	DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]	DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]	DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]
d2asea1_d4wzag___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	nitrogen fixation [GO:0009399]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	molybdenum-iron nitrogenase complex [GO:0016612]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2asnx2_d4edea___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	vasodilation [GO:0042311]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d2asra__d3atpb___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; positive regulation of post-translational protein modification [GO:1901875]; protein homooligomerization [GO:0051260]; regulation of chemotaxis [GO:0050920]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]; protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cell motility [GO:0048870]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; protein homooligomerization [GO:0051260]; receptor clustering [GO:0043113]; regulation of bacterial-type flagellum-dependent cell motility [GO:1902021]; regulation of chemotaxis [GO:0050920]; regulation of protein histidine kinase activity [GO:0032110]; response to amino acid [GO:0043200]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; positive regulation of post-translational protein modification [GO:1901875]; protein homooligomerization [GO:0051260]; regulation of chemotaxis [GO:0050920]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	cell motility [GO:0048870]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; protein homooligomerization [GO:0051260]; receptor clustering [GO:0043113]; regulation of bacterial-type flagellum-dependent cell motility [GO:1902021]; regulation of chemotaxis [GO:0050920]; regulation of protein histidine kinase activity [GO:0032110]; response to amino acid [GO:0043200]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]	protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]	protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]
d2assb2_d1a4ya___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]
d2astb2_d1k5di___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2asyb__d2hiqb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; oxidoreductase activity [GO:0016491]			cytosol [GO:0005829]	cytosol [GO:0005829]	oxidoreductase activity [GO:0016491]	oxidoreductase activity [GO:0016491]
d2at1a2_d1za2a2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2at1c1_d2i6ub1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d2at1d1_d1f1bd1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2at2a1_d4amua2__1			Firmicutes	Tenericutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d2at2a2_d1otha1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; phosphate ion binding [GO:0042301]; phospholipid binding [GO:0005543]; ammonia homeostasis [GO:0097272]; anion homeostasis [GO:0055081]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; liver development [GO:0001889]; midgut development [GO:0007494]; ornithine catabolic process [GO:0006593]; protein homotrimerization [GO:0070207]; response to biotin [GO:0070781]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	ammonia homeostasis [GO:0097272]; anion homeostasis [GO:0055081]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; liver development [GO:0001889]; midgut development [GO:0007494]; ornithine catabolic process [GO:0006593]; protein homotrimerization [GO:0070207]; response to biotin [GO:0070781]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; phosphate ion binding [GO:0042301]; phospholipid binding [GO:0005543]
d2at2b1_d3r7lc2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d2at2b2_d3e2pc2__1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d2at4x__d1sxya___1		Metazoa		Arthropoda		extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]		vasodilation [GO:0042311]		extracellular region [GO:0005576]		histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d2at4x__d5edca1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]		brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]		fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d2at6x__d1mdca___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	vasodilation [GO:0042311]		extracellular region [GO:0005576]	cytoplasm [GO:0005737]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	lipid binding [GO:0008289]
d2at7x__d3wbgb___1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]		cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]		cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]
d2ataa__d2ramb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]
d2atab__d1ooab2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2atad__d3wtxf___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]
d2atca1_d3m4na1__1			Proteobacteria	Proteobacteria	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]; zinc ion binding [GO:0008270]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]
d2atja__d3n8xb2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d2atjb__d1u2lb1__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]	cytosol [GO:0005829]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]
d2atjb__d1yzpa___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]	extracellular region [GO:0005576]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]
d2atka1_d4m93l1__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2atka1_d4o9hl1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	voltage-gated potassium channel complex [GO:0008076]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]
d2atkb1_d3quzc2__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	voltage-gated potassium channel complex [GO:0008076]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2atkb2_d5c3ta1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	voltage-gated potassium channel complex [GO:0008076]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2atoa__d4dhji___1	Metazoa	Metazoa	Chordata	Chordata	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2atpb1_d1zluh1__1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]	
d2atpc__d4zsoc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]	regulation of immune response [GO:0050776]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]	
d2atwc2_d2hgpf1__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]		DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]	
d2atxb__d5gvra___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi-associated vesicle membrane [GO:0030660]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; profilin binding [GO:0005522]; protein kinase binding [GO:0019901]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytosis [GO:0006897]; establishment or maintenance of cell polarity [GO:0007163]; GTP metabolic process [GO:0046039]; insulin receptor signaling pathway [GO:0008286]; negative regulation of protein localization to plasma membrane [GO:1903077]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of glucose import [GO:0046326]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to interferon-beta [GO:0035458]; defense response to virus [GO:0051607]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytosis [GO:0006897]; establishment or maintenance of cell polarity [GO:0007163]; GTP metabolic process [GO:0046039]; insulin receptor signaling pathway [GO:0008286]; negative regulation of protein localization to plasma membrane [GO:1903077]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of glucose import [GO:0046326]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to interferon-beta [GO:0035458]; defense response to virus [GO:0051607]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]	actin filament [GO:0005884]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi-associated vesicle membrane [GO:0030660]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; membrane [GO:0016020]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]	GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; profilin binding [GO:0005522]; protein kinase binding [GO:0019901]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]
d2atxb__d5uqwa___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi-associated vesicle membrane [GO:0030660]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; profilin binding [GO:0005522]; protein kinase binding [GO:0019901]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytosis [GO:0006897]; establishment or maintenance of cell polarity [GO:0007163]; GTP metabolic process [GO:0046039]; insulin receptor signaling pathway [GO:0008286]; negative regulation of protein localization to plasma membrane [GO:1903077]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of glucose import [GO:0046326]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]; actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytosis [GO:0006897]; establishment or maintenance of cell polarity [GO:0007163]; GTP metabolic process [GO:0046039]; insulin receptor signaling pathway [GO:0008286]; negative regulation of protein localization to plasma membrane [GO:1903077]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of glucose import [GO:0046326]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	actin filament [GO:0005884]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi-associated vesicle membrane [GO:0030660]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; profilin binding [GO:0005522]; protein kinase binding [GO:0019901]	GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]
d2auna2_d3l18b1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; carboxypeptidase activity [GO:0004180]; serine-type peptidase activity [GO:0008236]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]	peptidase activity [GO:0008233]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]		cytoplasm [GO:0005737]		carboxypeptidase activity [GO:0004180]; serine-type peptidase activity [GO:0008236]	peptidase activity [GO:0008233]
d2auoa__d1lfvb___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2aupa__d2vjha___1	Metazoa		Mollusca	Cyanobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2av1b2_d5cezl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d2av1d1_d5u17e1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2av1d2_d4grla1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2av3b__d4i0vb___1	Metazoa		Mollusca		cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2av4a1_d5lcza1__1		Metazoa	Apicomplexa	Chordata	U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; mRNA splicing, via spliceosome [GO:0000398]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	mRNA splicing, via spliceosome [GO:0000398]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2av7b2_d5fyle1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d2av8a__d5xhia___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2avaa__d4ihfh___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acyltransferase activity [GO:0016410]; UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity [GO:0103118]; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity [GO:0043764]; lipid A biosynthetic process [GO:0009245]; response to antibiotic [GO:0046677]	fatty acid biosynthetic process [GO:0006633]	lipid A biosynthetic process [GO:0009245]; response to antibiotic [GO:0046677]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	phosphopantetheine binding [GO:0031177]	identical protein binding [GO:0042802]; N-acyltransferase activity [GO:0016410]; UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity [GO:0103118]; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity [GO:0043764]
d2avfa1_d2iwea___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2avfa2_d2b08c2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2avfa2_d3cvdc___1			Proteobacteria	Cyanobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	thylakoid membrane [GO:0042651]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2avfb1_d1ndrb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2avfb2_d4n24a1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; chromatin-mediated maintenance of transcription [GO:0048096]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cellular response to leukemia inhibitory factor [GO:1990830]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin organization [GO:0006325]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]	periplasmic space [GO:0042597]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]
d2avfc1_d1mzya2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2avfc2_d1kgyg___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]	periplasmic space [GO:0042597]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2avfd1_d2j5wa5__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	periplasmic space [GO:0042597]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d2avfd1_d3fu8b3__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2avfe1_d1e67a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2avff1_d3v9ca3__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2avff1_d4mfhb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2avff2_d2bhfa2__1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	sporulation resulting in formation of a cellular spore [GO:0030435]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2avmb__d3el1b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2avmb__d5p0ya___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2avva__d5p2ia___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2avvd__d1sgza___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d2avvd__d3sa7b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2avve__d1hshc___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2avve__d2g94c___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d2avye2_d2hgrh2__1												
d2avyg1_d2e5lg1__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2avyi1_d1fjgi___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2avym1_d2hhhm1__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2avyt1_d1i97t___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2aw1a__d5fl4c___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2aw2a1_d3mlyl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine binding [GO:0019955]; tumor necrosis factor-activated receptor activity [GO:0005031]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of adaptive immune memory response [GO:1905675]; negative regulation of alpha-beta T cell proliferation [GO:0046642]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell migration [GO:2000406]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of adaptive immune memory response [GO:1905675]; negative regulation of alpha-beta T cell proliferation [GO:0046642]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell migration [GO:2000406]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		cytokine binding [GO:0019955]; tumor necrosis factor-activated receptor activity [GO:0005031]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	
d2aw2a1_d3qa3j1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine binding [GO:0019955]; tumor necrosis factor-activated receptor activity [GO:0005031]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of adaptive immune memory response [GO:1905675]; negative regulation of alpha-beta T cell proliferation [GO:0046642]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell migration [GO:2000406]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of adaptive immune memory response [GO:1905675]; negative regulation of alpha-beta T cell proliferation [GO:0046642]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell migration [GO:2000406]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cytokine binding [GO:0019955]; tumor necrosis factor-activated receptor activity [GO:0005031]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]
d2aw4d1_d2e1ra1__1		Fungi		Ascomycota		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]
d2aw4m1_d2qbkm1__1												
d2aw4o1_d1vq9n1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2aw4p1_d2zjqm1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2aw4s1_d1yjwr1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2aw4t1_d1ffki___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2aw4u1_d1vsps1__1												
d2aw5b1_d2hk8f1__1	Metazoa		Chordata	Aquificae	cytosol [GO:0005829]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; manganese ion binding [GO:0030145]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxaloacetate decarboxylase activity [GO:0008948]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; nucleotide biosynthetic process [GO:0009165]; pyruvate metabolic process [GO:0006090]; regulation of lipid metabolic process [GO:0019216]; regulation of NADP metabolic process [GO:1902031]; response to carbohydrate [GO:0009743]; response to hormone [GO:0009725]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; nucleotide biosynthetic process [GO:0009165]; pyruvate metabolic process [GO:0006090]; regulation of lipid metabolic process [GO:0019216]; regulation of NADP metabolic process [GO:1902031]; response to carbohydrate [GO:0009743]; response to hormone [GO:0009725]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	ADP binding [GO:0043531]; electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; manganese ion binding [GO:0030145]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxaloacetate decarboxylase activity [GO:0008948]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d2aw7c1_d1egab2__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; small ribosomal subunit rRNA binding [GO:0070181]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]		protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; small ribosomal subunit rRNA binding [GO:0070181]
d2aw7e2_d1xnqe2__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2aw7h1_d1i96h___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2aw7l1_d1l0wa1__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]		aspartyl-tRNA aminoacylation [GO:0006422]		cytoplasm [GO:0005737]		aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]
d2aw7o1_d1fjgo___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2aw9a1_d4yipc1__1			Deinococcus-Thermus	Firmicutes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2aw9b2_d3ak3a2__1			Deinococcus-Thermus	Crenarchaeota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2awbd1_d1k73d___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2awbd1_d4qfma2__1				Crenarchaeota		cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d2awbf1_d1xbpd1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2awbg2_d1vqoe2__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2awbq1_d2hgqt1__1												
d2awbr1_d1xbpp1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2awnc1_d3d31b1__1			Proteobacteria	Euryarchaeota	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]; activating transcription factor binding [GO:0033613]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; transmembrane transport [GO:0055085]	maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	activating transcription factor binding [GO:0033613]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; ATP binding [GO:0005524]	
d2awoa2_d2dftb___1			Proteobacteria	Actinobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]; activating transcription factor binding [GO:0033613]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]	cytosol [GO:0005829]	activating transcription factor binding [GO:0033613]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; ATP binding [GO:0005524]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]
d2awpa2_d6elkc2__1		Metazoa	Apicomplexa	Nematoda (roundworms)	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]		mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]
d2awpb2_d1qnmb2__1		Metazoa	Apicomplexa	Chordata	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2awpb2_d4gune2__1		Fungi	Apicomplexa	Ascomycota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2awta__d1km7a___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; synapse [GO:0045202]; beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; chemical synaptic transmission [GO:0007268]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein targeting [GO:0006605]	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; chemical synaptic transmission [GO:0007268]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein targeting [GO:0006605]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; synapse [GO:0045202]	RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]	beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d2awta__d2jy6a___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2awua__d2l4sa___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]; activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]	ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]	beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]
d2awwa__d2g2lb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]	ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]	ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]
d2awwb__d3dj3d___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]; activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]	beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]
d2awxa__d2kv8a___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	cell junction [GO:0030054]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTPase regulator activity [GO:0030695]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]	cell junction [GO:0030054]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]	ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTPase regulator activity [GO:0030695]
d2awxb__d4jojb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]	ion channel binding [GO:0044325]
d2ax5a__d1tygb___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein homodimerization activity [GO:0042803]; protein tag [GO:0031386]; sulfur carrier activity [GO:0097163]; cell budding [GO:0007114]; cellular response to oxidative stress [GO:0034599]; invasive growth in response to glucose limitation [GO:0001403]; protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble position uridine thiolation [GO:0002143]; tRNA wobble uridine modification [GO:0002098]	cytoplasm [GO:0005737]; sulfurtransferase activity [GO:0016783]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cell budding [GO:0007114]; cellular response to oxidative stress [GO:0034599]; invasive growth in response to glucose limitation [GO:0001403]; protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble position uridine thiolation [GO:0002143]; tRNA wobble uridine modification [GO:0002098]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	protein homodimerization activity [GO:0042803]; protein tag [GO:0031386]; sulfur carrier activity [GO:0097163]	sulfurtransferase activity [GO:0016783]
d2axfb__d1rmfl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2axga1_d1xfpa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2axgb__d1d6vh1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2axgb__d3v95b1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2axhb2_d5j75b1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2axja1_d1m71b1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2axja2_d1ls0b4__1												
d2axmb__d1g82d___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	basement membrane [GO:0005604]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; embryonic digestive tract development [GO:0048566]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inner ear morphogenesis [GO:0042472]; lung-associated mesenchyme development [GO:0060484]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; MAPK cascade [GO:0000165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein import into nucleus [GO:0006606]; regulation of timing of cell differentiation [GO:0048505]; signal transduction [GO:0007165]; substantia nigra development [GO:0021762]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; embryonic digestive tract development [GO:0048566]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inner ear morphogenesis [GO:0042472]; lung-associated mesenchyme development [GO:0060484]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; MAPK cascade [GO:0000165]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein import into nucleus [GO:0006606]; regulation of timing of cell differentiation [GO:0048505]; signal transduction [GO:0007165]; substantia nigra development [GO:0021762]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	basement membrane [GO:0005604]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]
d2axtv__d2ce0a___1		Viridiplantae	Cyanobacteria	Streptophyta	extrinsic component of membrane [GO:0019898]; photosystem II oxygen evolving complex [GO:0009654]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; photosystem II stabilization [GO:0042549]	chloroplast thylakoid lumen [GO:0009543]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem I [GO:0009773]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; photosystem II stabilization [GO:0042549]	photosynthetic electron transport in photosystem I [GO:0009773]	extrinsic component of membrane [GO:0019898]; photosystem II oxygen evolving complex [GO:0009654]	chloroplast thylakoid lumen [GO:0009543]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2axva1_d3s8qa___1			Firmicutes	Proteobacteria	transcriptional repressor complex [GO:0017053]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]	negative regulation of transcription, DNA-templated [GO:0045892]		transcriptional repressor complex [GO:0017053]		DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2axvb1_d3g5gm___1			Firmicutes	Proteobacteria	transcriptional repressor complex [GO:0017053]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]	negative regulation of transcription, DNA-templated [GO:0045892]		transcriptional repressor complex [GO:0017053]		DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2axvc2_d2grlb2__1			Firmicutes	Firmicutes	transcriptional repressor complex [GO:0017053]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]	transcriptional repressor complex [GO:0017053]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	transcriptional repressor complex [GO:0017053]	transcriptional repressor complex [GO:0017053]	DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2axvd1_d2iuoe1__1			Firmicutes	Proteobacteria	transcriptional repressor complex [GO:0017053]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	negative regulation of transcription, DNA-templated [GO:0045892]	cyanate catabolic process [GO:0009440]	transcriptional repressor complex [GO:0017053]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2axwb2_d2w5pa1__1			Proteobacteria	Proteobacteria		pilus [GO:0009289]				pilus [GO:0009289]		
d2ay3a__d1akaa___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]; aromatic amino acid family biosynthetic process [GO:0009073]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	aromatic amino acid family biosynthetic process [GO:0009073]	2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]	kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]
d2ay4a__d5ax8b___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]; aromatic amino acid family biosynthetic process [GO:0009073]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T-tubule [GO:0030315]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; RNA binding [GO:0003723]; 2-oxoglutarate metabolic process [GO:0006103]; 4-hydroxyproline catabolic process [GO:0019470]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glyoxylate metabolic process [GO:0046487]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]	aromatic amino acid family biosynthetic process [GO:0009073]	2-oxoglutarate metabolic process [GO:0006103]; 4-hydroxyproline catabolic process [GO:0019470]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glyoxylate metabolic process [GO:0046487]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]	cytoplasm [GO:0005737]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T-tubule [GO:0030315]	L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; RNA binding [GO:0003723]
d2ay6a__d1yaad___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]; aromatic amino acid family biosynthetic process [GO:0009073]	cytosol [GO:0005829]; peroxisome [GO:0005777]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; asparagine biosynthetic process from oxaloacetate [GO:0019266]; aspartate biosynthetic process [GO:0006532]; aspartate metabolic process [GO:0006531]; glutamate metabolic process [GO:0006536]	aromatic amino acid family biosynthetic process [GO:0009073]	2-oxoglutarate metabolic process [GO:0006103]; asparagine biosynthetic process from oxaloacetate [GO:0019266]; aspartate biosynthetic process [GO:0006532]; aspartate metabolic process [GO:0006531]; glutamate metabolic process [GO:0006536]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; peroxisome [GO:0005777]	L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]	L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]
d2ay6a__d3eiba1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]; aromatic amino acid family biosynthetic process [GO:0009073]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	aromatic amino acid family biosynthetic process [GO:0009073]	lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]	L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]	copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d2ay7a__d1arib___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]; aromatic amino acid family biosynthetic process [GO:0009073]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	aromatic amino acid family biosynthetic process [GO:0009073]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d2ayha__d4atfc1__1			Firmicutes	Bacteroidetes	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	cell outer membrane [GO:0009279]; beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		cell outer membrane [GO:0009279]	licheninase activity [GO:0042972]	beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]
d2ayha__d4ga9a___1		Metazoa	Firmicutes	Chordata	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of viral entry into host cell [GO:0046598]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	carbohydrate metabolic process [GO:0005975]	apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of viral entry into host cell [GO:0046598]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	licheninase activity [GO:0042972]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]
d2ayla1_d3ut2b2__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	extracellular region [GO:0005576]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2ayqb__d4zdab___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]		3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]
d2aytb1_d1r4wb___1		Metazoa	Aquificae	Chordata		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione metabolic process [GO:0006749]		epithelial cell differentiation [GO:0030855]; glutathione metabolic process [GO:0006749]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]
d2ayza1_d2pmcd___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; cellular response to osmotic stress [GO:0071470]; phosphorelay signal transduction system [GO:0000160]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]; single-species biofilm formation [GO:0044010]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cellular response to osmotic stress [GO:0071470]; phosphorelay signal transduction system [GO:0000160]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]; single-species biofilm formation [GO:0044010]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]	metal ion binding [GO:0046872]
d2az0a1_d2b9za1__1					RNA binding [GO:0003723]	RNA binding [GO:0003723]					RNA binding [GO:0003723]	RNA binding [GO:0003723]
d2az1a1_d4dz6b1__1			Euryarchaeota	Spirochaetes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2az3e__d1buxa___1			Euryarchaeota		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2az3h__d3ee3c1__1			Euryarchaeota		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2az4b1_d3ie1d___1			Firmicutes	Deinococcus-Thermus	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]		rRNA processing [GO:0006364]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2azca__d2qmpb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]
d2azcb__d1avf.1__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular space [GO:0005615]; aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; positive regulation of antibacterial peptide production [GO:0002803]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	digestion [GO:0007586]; positive regulation of antibacterial peptide production [GO:0002803]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular space [GO:0005615]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2azda__d1sxpa___1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; maltodextrin phosphorylase activity [GO:0031220]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]; alpha-glucan catabolic process [GO:0030980]; glycogen catabolic process [GO:0005980]	DNA beta-glucosyltransferase activity [GO:0033821]; DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]	alpha-glucan catabolic process [GO:0030980]; glycogen catabolic process [GO:0005980]	DNA modification [GO:0006304]; restriction-modification system evasion by virus [GO:0099018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; maltodextrin phosphorylase activity [GO:0031220]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]	DNA beta-glucosyltransferase activity [GO:0033821]
d2azla__d2f89f___1		Metazoa	Thermotogae	Chordata	transferase activity [GO:0016740]; isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	isoprenoid biosynthetic process [GO:0008299]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	transferase activity [GO:0016740]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2azpa1_d3ekme1__1		Viridiplantae	Proteobacteria	Streptophyta	4-hydroxyproline epimerase activity [GO:0047580]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]		lysine biosynthetic process via diaminopimelate [GO:0009089]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]	4-hydroxyproline epimerase activity [GO:0047580]	diaminopimelate epimerase activity [GO:0008837]
d2azra__d4yr8g___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	axon [GO:0030424]; basal dendrite [GO:0097441]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; JUN kinase activity [GO:0004705]; kinase activity [GO:0016301]; MAP kinase activity [GO:0004707]; protein serine/threonine kinase activity [GO:0004674]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; JUN phosphorylation [GO:0007258]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein binding [GO:0032091]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cyclase activity [GO:0031281]; positive regulation of deacetylase activity [GO:0090045]; positive regulation of gene expression [GO:0010628]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein metabolic process [GO:0051247]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of DNA replication origin binding [GO:1902595]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of gene expression [GO:0010468]; regulation of macroautophagy [GO:0016241]; regulation of protein localization [GO:0032880]; response to UV [GO:0009411]; rhythmic process [GO:0048511]; stress-activated MAPK cascade [GO:0051403]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; JUN phosphorylation [GO:0007258]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein binding [GO:0032091]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cyclase activity [GO:0031281]; positive regulation of deacetylase activity [GO:0090045]; positive regulation of gene expression [GO:0010628]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein metabolic process [GO:0051247]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of DNA replication origin binding [GO:1902595]; regulation of gene expression [GO:0010468]; regulation of macroautophagy [GO:0016241]; regulation of protein localization [GO:0032880]; response to UV [GO:0009411]; rhythmic process [GO:0048511]; stress-activated MAPK cascade [GO:0051403]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	axon [GO:0030424]; basal dendrite [GO:0097441]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; JUN kinase activity [GO:0004705]; kinase activity [GO:0016301]; MAP kinase activity [GO:0004707]; protein serine/threonine kinase activity [GO:0004674]
d2azua__d1mg2k___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2azub__d1rzqc1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2b00a__d3p2pb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]; bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]; bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]	bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]	bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]
d2b07a__d1fpzc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cell cycle arrest [GO:0007050]; cilium assembly [GO:0060271]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell population proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cell cycle arrest [GO:0007050]; cilium assembly [GO:0060271]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell population proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d2b08a2_d3t6xc3__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2b0ca1_d3i1ya1__1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphatase activity [GO:0008877]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	glucose-1-phosphatase activity [GO:0008877]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2b0ga1_d3egna___1	Metazoa	Metazoa	Arthropoda	Chordata	catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; small nuclear ribonucleoprotein complex [GO:0030532]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; pre-mRNA intronic pyrimidine-rich binding [GO:0097158]; snRNA stem-loop binding [GO:0035614]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; female germ-line sex determination [GO:0019099]; heterochromatin organization involved in chromatin silencing [GO:0070868]; mRNA splicing, via spliceosome [GO:0000398]; oogenesis [GO:0048477]; primary sex determination, soma [GO:0007539]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U12-type spliceosomal complex [GO:0005689]; pre-mRNA intronic binding [GO:0097157]; U12 snRNA binding [GO:0030626]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]	female germ-line sex determination [GO:0019099]; heterochromatin organization involved in chromatin silencing [GO:0070868]; mRNA splicing, via spliceosome [GO:0000398]; oogenesis [GO:0048477]; primary sex determination, soma [GO:0007539]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]	catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; small nuclear ribonucleoprotein complex [GO:0030532]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U12-type spliceosomal complex [GO:0005689]	identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; pre-mRNA intronic pyrimidine-rich binding [GO:0097158]; snRNA stem-loop binding [GO:0035614]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]	pre-mRNA intronic binding [GO:0097157]; U12 snRNA binding [GO:0030626]
d2b0sh1_d1zt4a1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2b0sh2_d1py4d___1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2b0ta__d2qfvc___1		Fungi	Actinobacteria	Ascomycota	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]		mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d2b0wb1_d1s89a___1				Proteobacteria		cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]		methylglyoxal biosynthetic process [GO:0019242]		cytosol [GO:0005829]		methylglyoxal synthase activity [GO:0008929]
d2b10a__d1ebea___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2b10d__d2c1va1__1	Fungi		Ascomycota		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	
d2b11a__d1itkb2__1	Fungi		Ascomycota	Euryarchaeota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2b11d__d1fcdd2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	periplasmic space [GO:0042597]; flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	periplasmic space [GO:0042597]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]
d2b12a__d3m2aa___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2b12b1_d1ceda___1	Fungi	Viridiplantae	Ascomycota	Chlorophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	chloroplast thylakoid lumen [GO:0009543]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	photosynthesis [GO:0015979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	chloroplast thylakoid lumen [GO:0009543]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2b14b__d5u49a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d2b16b__d3cn4b___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d2b16b__d3q1ea___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d2b1ah1_d1g6rm___1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	structural molecule activity [GO:0005198]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2b1ah2_d5u15l1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d2b1gb1_d1bxrc2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2b1gd1_d1c30e2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2b1gd2_d2jywa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	'de novo' IMP biosynthetic process [GO:0006189]	base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	cytosol [GO:0005829]	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2b1hh2_d5e7fc1__1												
d2b1ia1_d1s8af___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	'de novo' IMP biosynthetic process [GO:0006189]	methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]	cytosol [GO:0005829]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	methylglyoxal synthase activity [GO:0008929]
d2b1ia2_d2z3jb___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	'de novo' IMP biosynthetic process [GO:0006189]	response to antibiotic [GO:0046677]	cytosol [GO:0005829]		IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d2b1ja__d3eulb___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	DNA binding [GO:0003677]
d2b1ka__d1xwbb___1		Metazoa	Proteobacteria	Arthropoda	cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; nucleus [GO:0005634]	disulfide oxidoreductase activity [GO:0015036]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]
d2b1ka__d2v32d___1		Metazoa	Proteobacteria	Annelida	cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]	disulfide oxidoreductase activity [GO:0015036]	peroxiredoxin activity [GO:0051920]
d2b1lb__d3tkrg___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	disulfide oxidoreductase activity [GO:0015036]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d2b1qa__d4y2ya1__1		Metazoa	Cyanobacteria	Chordata	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]; sucrose biosynthetic process [GO:0005986]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	sucrose biosynthetic process [GO:0005986]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2b1xb1_d1idpb___1		Fungi	Actinobacteria	Ascomycota	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	endosome [GO:0005768]; metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]; melanin biosynthetic process [GO:0042438]	cellular metabolic process [GO:0044237]	melanin biosynthetic process [GO:0042438]		endosome [GO:0005768]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]	metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]
d2b1xb1_d4hm5b___1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]	dioxygenase activity [GO:0051213]
d2b24a1_d2yvjb___1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2b24a2_d1z01b2__1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	cellular metabolic process [GO:0044237]				2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d2b2gb__d2quxm___1					T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	viral capsid [GO:0019028]	regulation of translation [GO:0006417]		T=3 icosahedral viral capsid [GO:0039617]	viral capsid [GO:0019028]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	
d2b2la2_d1h0gb3__1				Proteobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d2b2xl1_d1i7tb2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2b2xl1_d4dzbb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2b2xl2_d1i8mh1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2b2xm1_d1bwwa___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]
d2b30b__d2i54c___1			Apicomplexa		hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]; GDP-mannose biosynthetic process [GO:0009298]		GDP-mannose biosynthetic process [GO:0009298]		cytoplasm [GO:0005737]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]
d2b33b__d1jd1f___1		Fungi	Thermotogae	Ascomycota	cytosol [GO:0005829]; deaminase activity [GO:0019239]; metal ion binding [GO:0046872]; organonitrogen compound catabolic process [GO:1901565]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	organonitrogen compound catabolic process [GO:1901565]	organonitrogen compound catabolic process [GO:1901565]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	deaminase activity [GO:0019239]; metal ion binding [GO:0046872]	deaminase activity [GO:0019239]
d2b33b__d1odeb___1			Thermotogae	Deinococcus-Thermus	cytosol [GO:0005829]; deaminase activity [GO:0019239]; metal ion binding [GO:0046872]; organonitrogen compound catabolic process [GO:1901565]	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	organonitrogen compound catabolic process [GO:1901565]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	deaminase activity [GO:0019239]; metal ion binding [GO:0046872]	chorismate mutase activity [GO:0004106]
d2b34a__d1x9ga1__1	Metazoa		Nematoda (roundworms)		cytoplasm [GO:0005737]; catalytic activity [GO:0003824]	catalytic activity [GO:0003824]			cytoplasm [GO:0005737]		catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d2b34e__d1nbac___1	Metazoa		Nematoda (roundworms)	Actinobacteria	cytoplasm [GO:0005737]; catalytic activity [GO:0003824]	N-carbamoylsarcosine amidase activity [GO:0050127]; creatinine catabolic process [GO:0006602]		creatinine catabolic process [GO:0006602]	cytoplasm [GO:0005737]		catalytic activity [GO:0003824]	N-carbamoylsarcosine amidase activity [GO:0050127]
d2b34f__d1j2ra___1	Metazoa		Nematoda (roundworms)	Proteobacteria	cytoplasm [GO:0005737]; catalytic activity [GO:0003824]	cytosol [GO:0005829]; hydrolase activity [GO:0016787]			cytoplasm [GO:0005737]	cytosol [GO:0005829]	catalytic activity [GO:0003824]	hydrolase activity [GO:0016787]
d2b3ia__d1bxaa___1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2b3ia__d5b1ja1__1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	thylakoid membrane [GO:0042651]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2b3ja1_d3v4jb___1		Metazoa	Firmicutes	Chordata	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	tRNA wobble adenosine to inosine editing [GO:0002100]	base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]		apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2b3jc__d2b3za2__1			Firmicutes	Firmicutes	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	tRNA wobble adenosine to inosine editing [GO:0002100]	riboflavin biosynthetic process [GO:0009231]			tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d2b3jd__d2fr5a___1		Metazoa	Firmicutes	Chordata	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]	tRNA wobble adenosine to inosine editing [GO:0002100]	cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]		cytosol [GO:0005829]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]
d2b3oa1_d1ayda___1	Metazoa	Metazoa	Chordata	Chordata	alpha-beta T cell receptor complex [GO:0042105]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cell adhesion molecule binding [GO:0050839]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; abortive mitotic cell cycle [GO:0033277]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein dephosphorylation [GO:0006470]; regulation of B cell differentiation [GO:0045577]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]; abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axonogenesis [GO:0007409]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; intestinal epithelial cell migration [GO:0061582]; lipid metabolic process [GO:0006629]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of hormone secretion [GO:0046888]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of signal transduction [GO:0009967]; positive regulation of tumor necrosis factor production [GO:0032760]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; triglyceride metabolic process [GO:0006641]	abortive mitotic cell cycle [GO:0033277]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein dephosphorylation [GO:0006470]; regulation of B cell differentiation [GO:0045577]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axonogenesis [GO:0007409]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; intestinal epithelial cell migration [GO:0061582]; lipid metabolic process [GO:0006629]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of hormone secretion [GO:0046888]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of signal transduction [GO:0009967]; positive regulation of tumor necrosis factor production [GO:0032760]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; triglyceride metabolic process [GO:0006641]	alpha-beta T cell receptor complex [GO:0042105]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cell adhesion molecule binding [GO:0050839]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]
d2b3sa__d2ayta1__1			Proteobacteria	Aquificae	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]		cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]		cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]		protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	
d2b3ta__d1sg9b___1			Proteobacteria	Thermotogae	nucleic acid binding [GO:0003676]; protein methyltransferase activity [GO:0008276]; protein-(glutamine-N5) methyltransferase activity [GO:0102559]; protein-glutamine N-methyltransferase activity [GO:0036009]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; peptidyl-glutamine methylation [GO:0018364]; protein methylation [GO:0006479]; regulation of gene expression [GO:0010468]; translational termination [GO:0006415]	nucleic acid binding [GO:0003676]; protein-(glutamine-N5) methyltransferase activity [GO:0102559]; protein-glutamine N-methyltransferase activity [GO:0036009]; peptidyl-glutamine methylation [GO:0018364]	peptidyl-glutamine methylation [GO:0018364]; protein methylation [GO:0006479]; regulation of gene expression [GO:0010468]; translational termination [GO:0006415]	peptidyl-glutamine methylation [GO:0018364]			nucleic acid binding [GO:0003676]; protein-(glutamine-N5) methyltransferase activity [GO:0102559]; protein-glutamine N-methyltransferase activity [GO:0036009]; protein methyltransferase activity [GO:0008276]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	nucleic acid binding [GO:0003676]; protein-(glutamine-N5) methyltransferase activity [GO:0102559]; protein-glutamine N-methyltransferase activity [GO:0036009]
d2b3ta__d3ieib___1		Metazoa	Proteobacteria	Chordata	nucleic acid binding [GO:0003676]; protein methyltransferase activity [GO:0008276]; protein-(glutamine-N5) methyltransferase activity [GO:0102559]; protein-glutamine N-methyltransferase activity [GO:0036009]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; peptidyl-glutamine methylation [GO:0018364]; protein methylation [GO:0006479]; regulation of gene expression [GO:0010468]; translational termination [GO:0006415]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; C-terminal protein methylation [GO:0006481]; cellular protein modification process [GO:0006464]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	peptidyl-glutamine methylation [GO:0018364]; protein methylation [GO:0006479]; regulation of gene expression [GO:0010468]; translational termination [GO:0006415]	cellular protein modification process [GO:0006464]; C-terminal protein methylation [GO:0006481]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]	nucleic acid binding [GO:0003676]; protein-(glutamine-N5) methyltransferase activity [GO:0102559]; protein-glutamine N-methyltransferase activity [GO:0036009]; protein methyltransferase activity [GO:0008276]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d2b3zc2_d4lcob1__1			Firmicutes	Proteobacteria	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]	riboflavin biosynthetic process [GO:0009231]				5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]
d2b3zd2_d2nx8a___1			Firmicutes	Firmicutes	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	riboflavin biosynthetic process [GO:0009231]	tRNA wobble adenosine to inosine editing [GO:0002100]			5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]
d2b45x__d1ww5c___1		Fungi	Firmicutes	Basidiomycota	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	xylan catabolic process [GO:0045493]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			endo-1,4-beta-xylanase activity [GO:0031176]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d2b49a__d3i80a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine phosphatase activity [GO:0004725]; sodium channel regulator activity [GO:0017080]; liver regeneration [GO:0097421]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of mitotic cell cycle [GO:0045930]; protein dephosphorylation [GO:0006470]; regulation of membrane depolarization during action potential [GO:0098902]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	liver regeneration [GO:0097421]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of mitotic cell cycle [GO:0045930]; protein dephosphorylation [GO:0006470]; regulation of membrane depolarization during action potential [GO:0098902]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine phosphatase activity [GO:0004725]; sodium channel regulator activity [GO:0017080]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2b4cc1_d3ln5b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2b4ka1_d2vzua1__1			Proteobacteria	Actinobacteria	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2b4kc2_d5am4a2__1		Metazoa	Proteobacteria	Chordata	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2b4kd1_d2vzta1__1			Proteobacteria	Actinobacteria	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2b4kd2_d2hrrc___1		Metazoa	Proteobacteria	Chordata	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d2b4ob__d1xxva1__1			Firmicutes	Proteobacteria	protein tyrosine phosphatase activity [GO:0004725]	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]	protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d2b4pa1_d4wu2b___1			Firmicutes	Firmicutes	protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]					protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d2b4rr2_d3pwkb2__1			Apicomplexa		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]				glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	
d2b4to2_d1gd1p2__1			Apicomplexa	Firmicutes	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2b4tp2_d1nboa2__1		Viridiplantae	Apicomplexa	Streptophyta	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2b4za__d1mg3d___1	Metazoa		Chordata	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	apoptotic process [GO:0006915]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2b51a2_d1fa0a3__1		Fungi		Ascomycota		mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]		mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]		mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d2b54a__d4fzab1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; serine/threonine protein kinase complex [GO:1902554]; kinase binding [GO:0019900]; protein kinase activator activity [GO:0030295]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674]; cell cycle arrest [GO:0007050]; cellular hypotonic response [GO:0071476]; intracellular signal transduction [GO:0035556]; negative regulation of potassium ion transmembrane transport [GO:1901380]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; neutrophil degranulation [GO:0043312]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein heterooligomerization [GO:0051291]; signal transduction by protein phosphorylation [GO:0023014]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell cycle arrest [GO:0007050]; cellular hypotonic response [GO:0071476]; intracellular signal transduction [GO:0035556]; negative regulation of potassium ion transmembrane transport [GO:1901380]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; neutrophil degranulation [GO:0043312]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein heterooligomerization [GO:0051291]; signal transduction by protein phosphorylation [GO:0023014]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; serine/threonine protein kinase complex [GO:1902554]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	kinase binding [GO:0019900]; protein kinase activator activity [GO:0030295]; protein serine/threonine kinase activator activity [GO:0043539]; protein serine/threonine kinase activity [GO:0004674]
d2b56a2_d1ueta1__1				Euryarchaeota		ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]		RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]				ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]
d2b59a1_d5gxya2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cell wall organization [GO:0071555]; cellulose catabolic process [GO:0030245]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]; cell wall organization [GO:0071555]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2b59b2_d5g5db1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cell wall organization [GO:0071555]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cell wall organization [GO:0071555]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]; cell wall organization [GO:0071555]	cellulose catabolic process [GO:0030245]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2b59b2_d5m0yb1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cell wall organization [GO:0071555]; cellulose catabolic process [GO:0030245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]; cell wall organization [GO:0071555]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2b5aa1_d2bnna1__1				Actinobacteria		dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]				dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d2b5aa1_d3vk0b___1				Proteobacteria		DNA binding [GO:0003677]						DNA binding [GO:0003677]
d2b5ad__d1zzcb1__1				Actinobacteria		dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]				dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d2b5dx2_d3ejta1__1		Metazoa		Arthropoda		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d2b5ea2_d3gssa2__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; unfolded protein binding [GO:0051082]; cell redox homeostasis [GO:0045454]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; protein alpha-1,2-demannosylation [GO:0036508]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; protein alpha-1,2-demannosylation [GO:0036508]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; unfolded protein binding [GO:0051082]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2b5ib2_d4lptd1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]; interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]		activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]		external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]		interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]	
d2b5ic2_d2edea1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]; interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	axon [GO:0030424]; cytosol [GO:0005829]; integral component of postsynaptic density membrane [GO:0099061]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; netrin receptor activity [GO:0005042]; transmembrane signaling receptor activity [GO:0004888]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dorsal/ventral axon guidance [GO:0033563]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of netrin-activated signaling pathway [GO:1902842]; negative regulation of neuron projection development [GO:0010977]; neuron migration [GO:0001764]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of neuron death [GO:1901214]; spinal cord ventral commissure morphogenesis [GO:0021965]	activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dorsal/ventral axon guidance [GO:0033563]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of netrin-activated signaling pathway [GO:1902842]; negative regulation of neuron projection development [GO:0010977]; neuron migration [GO:0001764]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of neuron death [GO:1901214]; spinal cord ventral commissure morphogenesis [GO:0021965]	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]	axon [GO:0030424]; cytosol [GO:0005829]; integral component of postsynaptic density membrane [GO:0099061]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]	netrin receptor activity [GO:0005042]; transmembrane signaling receptor activity [GO:0004888]
d2b5la4_d5he3b___1	Metazoa	Metazoa	Chordata	Chordata	Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; Cul4A-RING E3 ubiquitin ligase complex [GO:0031464]; Cul4B-RING E3 ubiquitin ligase complex [GO:0031465]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cullin family protein binding [GO:0097602]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; protein binding, bridging [GO:0030674]; protein-containing complex binding [GO:0044877]; WD40-repeat domain binding [GO:0071987]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; histone H2A monoubiquitination [GO:0035518]; interaction with symbiont [GO:0051702]; negative regulation of apoptotic process [GO:0043066]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral release from host cell [GO:1902188]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of mitotic cell cycle phase transition [GO:1901990]; rhythmic process [GO:0048511]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]; alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]; cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein phosphorylation [GO:0006468]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; histone H2A monoubiquitination [GO:0035518]; interaction with symbiont [GO:0051702]; negative regulation of apoptotic process [GO:0043066]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral release from host cell [GO:1902188]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of mitotic cell cycle phase transition [GO:1901990]; rhythmic process [GO:0048511]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein phosphorylation [GO:0006468]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	Cul4A-RING E3 ubiquitin ligase complex [GO:0031464]; Cul4B-RING E3 ubiquitin ligase complex [GO:0031465]; Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]	cullin family protein binding [GO:0097602]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; protein binding, bridging [GO:0030674]; protein-containing complex binding [GO:0044877]; WD40-repeat domain binding [GO:0071987]	alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]
d2b5oa1_d1i7pa1__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]	endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; mitochondrial outer membrane [GO:0005741]; ADP binding [GO:0043531]; AMP binding [GO:0016208]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; cholesterol biosynthetic process [GO:0006695]		cholesterol biosynthetic process [GO:0006695]	phycobilisome [GO:0030089]	endoplasmic reticulum membrane [GO:0005789]; lipid droplet [GO:0005811]; mitochondrial outer membrane [GO:0005741]	ferredoxin-NADP+ reductase activity [GO:0004324]	ADP binding [GO:0043531]; AMP binding [GO:0016208]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]
d2b5oa1_d3w5ue1__1		Viridiplantae	Cyanobacteria	Streptophyta	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]		electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	phycobilisome [GO:0030089]	chloroplast thylakoid membrane protein complex [GO:0098807]	ferredoxin-NADP+ reductase activity [GO:0004324]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d2b5ob1_d1f20a1__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]; ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]		aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	phycobilisome [GO:0030089]	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]	ferredoxin-NADP+ reductase activity [GO:0004324]	ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]
d2b5ob2_d1ep1b2__1			Cyanobacteria	Firmicutes	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]	cytoplasm [GO:0005737]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' UMP biosynthetic process [GO:0044205]	phycobilisome [GO:0030089]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]
d2b5xa1_d3pina___1		Fungi	Firmicutes	Ascomycota	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; glutathione metabolic process [GO:0006749]; glycerol ether metabolic process [GO:0006662]; protein deglutathionylation [GO:0080058]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; sulfate assimilation [GO:0000103]; vacuole fusion, non-autophagic [GO:0042144]; vacuole inheritance [GO:0000011]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; glutathione metabolic process [GO:0006749]; glycerol ether metabolic process [GO:0006662]; protein deglutathionylation [GO:0080058]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; sulfate assimilation [GO:0000103]; vacuole fusion, non-autophagic [GO:0042144]; vacuole inheritance [GO:0000011]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]
d2b60b__d1uh7a___1		Fungi		Mucoromycota	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]
d2b60b__d3sa8a___1					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]
d2b64b1_d2om7n1__1				Deinococcus-Thermus		small ribosomal subunit [GO:0015935]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		small ribosomal subunit [GO:0015935]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2b64d1_d2avyd1__1												
d2b64m1_d2z4mm1__1												
d2b66h1_d3d5bh2__1												
d2b6aa2_d5vqza2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2b6bd1_d4n32c___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d2b6fa__d5x0ka___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]; cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; cysteine biosynthetic process [GO:0019344]	cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	cysteine biosynthetic process [GO:0019344]	cytosol [GO:0005829]		ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]	ATP binding [GO:0005524]; kinase activity [GO:0016301]
d2b6mb__d3gurb1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]
d2b6na__d3d43a___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2b6za__d5i5qa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2b76b1_d4ysyf2__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d2b76b2_d2fbwo1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d2b7ca1_d6b8da2__1	Fungi		Ascomycota	Proteobacteria	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]		cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]	cytoplasm [GO:0005737]	guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2b7ca2_d4rjla3__1	Fungi		Ascomycota	Crenarchaeota	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]	cytosol [GO:0005829]	guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d2b7jb__d1m0ua2__1	Fungi	Metazoa	Ascomycota	Arthropoda	cell [GO:0005623]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; copper ion binding [GO:0005507]; cell redox homeostasis [GO:0045454]; cellular copper ion homeostasis [GO:0006878]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; prostaglandin-D synthase activity [GO:0004667]; glutathione metabolic process [GO:0006749]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; cellular copper ion homeostasis [GO:0006878]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]	glutathione metabolic process [GO:0006749]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	copper ion binding [GO:0005507]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; prostaglandin-D synthase activity [GO:0004667]
d2b7kd__d3ik9e1__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; copper ion binding [GO:0005507]; cell redox homeostasis [GO:0045454]; cellular copper ion homeostasis [GO:0006878]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular copper ion homeostasis [GO:0006878]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	copper ion binding [GO:0005507]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2b7la__d1n1da___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cytoplasm [GO:0005737]; glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]	glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]
d2b7la__d3mlba___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	cell wall organization [GO:0071555]; teichoic acid biosynthetic process [GO:0019350]	NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]		glycerol-3-phosphate cytidylyltransferase activity [GO:0047348]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]
d2b7nb1_d2im5d1__1			Proteobacteria	Bacteroidetes	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]
d2b7nb2_d1qpoc1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2b7pa1_d1qpnf2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2b7pc1_d1qpra2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2b7pc2_d1qpnd1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2b7ra3_d2bs4d3__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	tricarboxylic acid cycle [GO:0006099]	outer membrane-bounded periplasmic space [GO:0030288]	respirasome [GO:0070469]	electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d2b7sa3_d2wu2a2__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	outer membrane-bounded periplasmic space [GO:0030288]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	electron transfer activity [GO:0009055]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; succinate dehydrogenase activity [GO:0000104]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d2b7ta1_d2dmya1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251]; adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; brain development [GO:0007420]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; positive regulation of mRNA processing [GO:0050685]; positive regulation of viral genome replication [GO:0045070]; regulation of cell cycle [GO:0051726]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; manchette [GO:0002177]; nucleus [GO:0005634]; DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; microtubule binding [GO:0008017]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; mechanosensory behavior [GO:0007638]; multicellular organism development [GO:0007275]; spermatid development [GO:0007286]	adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; brain development [GO:0007420]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; positive regulation of mRNA processing [GO:0050685]; positive regulation of viral genome replication [GO:0045070]; regulation of cell cycle [GO:0051726]; RNA processing [GO:0006396]	mechanosensory behavior [GO:0007638]; multicellular organism development [GO:0007275]; spermatid development [GO:0007286]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; manchette [GO:0002177]; nucleus [GO:0005634]	double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251]	DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; microtubule binding [GO:0008017]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]
d2b7va1_d2nugb2__1	Metazoa		Chordata	Aquificae	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251]; adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; brain development [GO:0007420]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; positive regulation of mRNA processing [GO:0050685]; positive regulation of viral genome replication [GO:0045070]; regulation of cell cycle [GO:0051726]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]; mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; brain development [GO:0007420]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; positive regulation of mRNA processing [GO:0050685]; positive regulation of viral genome replication [GO:0045070]; regulation of cell cycle [GO:0051726]; RNA processing [GO:0006396]	mRNA processing [GO:0006397]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251]	double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; ribonuclease III activity [GO:0004525]
d2b83b2_d5b12e___1			Firmicutes	Actinobacteria	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]					isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d2b83d2_d3orfa___1			Firmicutes		isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; phagocytic vesicle [GO:0045335]; 6,7-dihydropteridine reductase activity [GO:0004155]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; L-phenylalanine catabolic process [GO:0006559]; response to oxidative stress [GO:0006979]; tetrahydrobiopterin biosynthetic process [GO:0006729]		L-phenylalanine catabolic process [GO:0006559]; response to oxidative stress [GO:0006979]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cytoplasm [GO:0005737]; phagocytic vesicle [GO:0045335]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	6,7-dihydropteridine reductase activity [GO:0004155]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]
d2b8hb__d2hu0h___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2b8hc__d4mc7a___1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	
d2b8hd__d4cpna___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2b8ja__d1z5ga1__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]			outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]	acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]
d2b8kc2_d2a69l2__1	Fungi		Ascomycota	Deinococcus-Thermus	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]	transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]		DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d2b8pb1_d3ngth___1					ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d2b8pb1_d4anee___1				Actinobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]
d2b8qb1_d3l7uc___1		Metazoa		Chordata	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]; cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]		cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]
d2b8qf1_d3fbff1__1					ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2b8xa__d1a7ma___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]; activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	cytosol [GO:0005829]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; leukemia inhibitory factor receptor binding [GO:0005146]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; astrocyte differentiation [GO:0048708]; blood vessel remodeling [GO:0001974]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; immune response [GO:0006955]; leukemia inhibitory factor signaling pathway [GO:0048861]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung vasculature development [GO:0060426]; maternal process involved in female pregnancy [GO:0060135]; muscle organ morphogenesis [GO:0048644]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of hormone secretion [GO:0046888]; negative regulation of meiotic nuclear division [GO:0045835]; neuron development [GO:0048666]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of corticotropin secretion [GO:0051461]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K27 acetylation [GO:1901676]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0072108]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell differentiation [GO:0045595]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025]; retina development in camera-type eye [GO:0060041]; spongiotrophoblast differentiation [GO:0060708]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]; transdifferentiation [GO:0060290]; trophoblast giant cell differentiation [GO:0060707]; tyrosine phosphorylation of STAT protein [GO:0007260]	activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	animal organ regeneration [GO:0031100]; astrocyte differentiation [GO:0048708]; blood vessel remodeling [GO:0001974]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; immune response [GO:0006955]; leukemia inhibitory factor signaling pathway [GO:0048861]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung vasculature development [GO:0060426]; maternal process involved in female pregnancy [GO:0060135]; muscle organ morphogenesis [GO:0048644]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of hormone secretion [GO:0046888]; negative regulation of meiotic nuclear division [GO:0045835]; neuron development [GO:0048666]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of corticotropin secretion [GO:0051461]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K27 acetylation [GO:1901676]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0072108]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell differentiation [GO:0045595]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025]; retina development in camera-type eye [GO:0060041]; spongiotrophoblast differentiation [GO:0060708]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]; transdifferentiation [GO:0060290]; trophoblast giant cell differentiation [GO:0060707]; tyrosine phosphorylation of STAT protein [GO:0007260]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytosol [GO:0005829]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; leukemia inhibitory factor receptor binding [GO:0005146]; signaling receptor binding [GO:0005102]
d2b8za__d1d9ca___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]; activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]; adaptive immune response [GO:0002250]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of protein ADP-ribosylation [GO:0010835]	activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	adaptive immune response [GO:0002250]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of protein ADP-ribosylation [GO:0010835]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular space [GO:0005615]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]	cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]
d2b90a__d1gnca___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]; activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]	cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]
d2b91a__d1pvhd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]; activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]	ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]
d2b97a__d4bwha1__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; spore wall [GO:0031160]	extracellular region [GO:0005576]			extracellular region [GO:0005576]; spore wall [GO:0031160]	extracellular region [GO:0005576]		
d2b9mb1_d2v48b1__1												
d2b9mh1_d1s03h___1				Proteobacteria		cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; regulation of mRNA stability [GO:0043488]; regulation of translation [GO:0006417]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]		regulation of mRNA stability [GO:0043488]; regulation of translation [GO:0006417]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]		cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2b9mq1_d1i97q___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2b9n21_d1q86w___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2b9ni1_d2z4lh1__1												
d2b9nk2_d1vs6i2__1												
d2b9ny1_d1kc8u___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2b9nz1_d2qaov1__1												
d2b9oc2_d2aw7c2__1												
d2b9ol1_d1gm5a2__1				Thermotogae		ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; nucleic acid binding [GO:0003676]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]		DNA recombination [GO:0006310]; DNA repair [GO:0006281]				ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; nucleic acid binding [GO:0003676]
d2b9oq1_d2qoyq1__1												
d2b9ua__d4hmzd1__1			Crenarchaeota	Actinobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; antibiotic biosynthetic process [GO:0017000]; carbohydrate metabolic process [GO:0005975]	dTDP-rhamnose biosynthetic process [GO:0019305]	antibiotic biosynthetic process [GO:0017000]; carbohydrate metabolic process [GO:0005975]			dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d2b9ub__d2ixca___1			Crenarchaeota	Actinobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]	dTDP-rhamnose biosynthetic process [GO:0019305]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]			dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d2b9uc__d2ixlc___1			Crenarchaeota	Firmicutes	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-rhamnose biosynthetic process [GO:0019305]				dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d2b9ud__d4uxab___1			Crenarchaeota	Acidobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]	metal ion binding [GO:0046872]	dTDP-rhamnose biosynthetic process [GO:0019305]				dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	metal ion binding [GO:0046872]
d2b9uf__d4aq6f___1			Crenarchaeota	Proteobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	dTDP-rhamnose biosynthetic process [GO:0019305]	L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]		protein-DNA complex [GO:0032993]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2b9ug__d1nzcd___1			Crenarchaeota	Firmicutes	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-rhamnose biosynthetic process [GO:0019305]				dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d2b9uh__d2pamb___1			Crenarchaeota	Firmicutes	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]	isomerase activity [GO:0016853]	dTDP-rhamnose biosynthetic process [GO:0019305]				dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	isomerase activity [GO:0016853]
d2b9uh__d4hn0c1__1			Crenarchaeota	Actinobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; antibiotic biosynthetic process [GO:0017000]; carbohydrate metabolic process [GO:0005975]	dTDP-rhamnose biosynthetic process [GO:0019305]	antibiotic biosynthetic process [GO:0017000]; carbohydrate metabolic process [GO:0005975]			dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d2b9ul__d4piya___1		Metazoa	Crenarchaeota	Chordata	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	dTDP-rhamnose biosynthetic process [GO:0019305]	cysteine metabolic process [GO:0006534]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]		cytosol [GO:0005829]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d2b9va1_d1l7ra1__1			Proteobacteria	Actinobacteria	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]		cocaine catabolic process [GO:0050784]		cytoplasm [GO:0005737]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]
d2b9vf1_d1jyyc3__1			Proteobacteria		alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]						alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	
d2b9vg1_d1jz1o3__1			Proteobacteria		alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]						alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	
d2b9vh1_d1px3a3__1			Proteobacteria	Proteobacteria	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2b9vj1_d3x29d___1			Proteobacteria	Firmicutes	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	extracellular region [GO:0005576]; toxin activity [GO:0090729]				extracellular region [GO:0005576]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	toxin activity [GO:0090729]
d2b9vk1_d1ghon3__1			Proteobacteria		alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]						alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	
d2b9vl1_d1oh3b___1		Fungi	Proteobacteria	Chytridiomycota	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]						alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	
d2b9vn1_d3jxsa___1			Proteobacteria	Bacteroidetes	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2b9vo1_d5c71b1__1		Fungi	Proteobacteria	Ascomycota	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2b9vp1_d4jkka1__1			Proteobacteria	Firmicutes	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2ba0d1_d2jebb1__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	RNA catabolic process [GO:0006401]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d2ba0h2_d1oyre2__1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	RNA catabolic process [GO:0006401]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]		3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d2ba1d2_d2pnza2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	RNA catabolic process [GO:0006401]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]
d2ba1f2_d1udna2__1			Euryarchaeota	Aquificae	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]		RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d2ba1f2_d2c38i2__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasmic exosome (RNase complex) [GO:0000177]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]
d2ba1g2_d2jeba2__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d2ba1i2_d2wnre2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	RNA catabolic process [GO:0006401]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]
d2ba4b__d1erzb___1				Proteobacteria		N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]
d2ba5a__d5h8ik___1		Viridiplantae		Streptophyta		N-carbamoylputrescine amidase activity [GO:0050126]; polyamine biosynthetic process [GO:0006596]		polyamine biosynthetic process [GO:0006596]				N-carbamoylputrescine amidase activity [GO:0050126]
d2ba5b__d5h8jc___1		Viridiplantae		Streptophyta		N-carbamoylputrescine amidase activity [GO:0050126]; polyamine biosynthetic process [GO:0006596]		polyamine biosynthetic process [GO:0006596]				N-carbamoylputrescine amidase activity [GO:0050126]
d2ba5c__d2e11a___1				Proteobacteria		2-oxoglutaramate amidase activity [GO:0106008]; omega-amidase activity [GO:0050152]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				2-oxoglutaramate amidase activity [GO:0106008]; omega-amidase activity [GO:0050152]
d2baaa__d2ou8a___1	Viridiplantae		Streptophyta		chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]	chitinase activity [GO:0004568]	lysozyme activity [GO:0003796]
d2baaa__d4tx7a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]			chitinase activity [GO:0004568]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d2bahc2_d2dw7a1__1				Proteobacteria		D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]		protein homooligomerization [GO:0051260]				D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]
d2bana2_d1i39a___1				Euryarchaeota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]; manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; RNA catabolic process [GO:0006401]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	RNA catabolic process [GO:0006401]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d2baxa__d1mc2a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]
d2bazb__d1pkkb___1			Firmicutes	Euryarchaeota	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d2bb2a1_d2jdga1__1	Metazoa	Metazoa	Chordata	Chordata	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; lens fiber cell morphogenesis [GO:0070309]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; lens fiber cell morphogenesis [GO:0070309]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d2bb2a2_d3so0b___1	Metazoa		Chordata	Firmicutes	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d2bb9b__d4cpra___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2bbba__d4djya___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d2bbbb__d1dazd___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2bbjf1_d4i0ui1__1			Thermotogae	Thermotogae	integral component of plasma membrane [GO:0005887]; cobalt ion binding [GO:0050897]; cobalt ion transmembrane transporter activity [GO:0015087]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; magnesium ion transmembrane transporter activity [GO:0015095]; cobalt ion transport [GO:0006824]; magnesium ion transmembrane transport [GO:1903830]; protein homooligomerization [GO:0051260]	integral component of plasma membrane [GO:0005887]; cobalt ion binding [GO:0050897]; cobalt ion transmembrane transporter activity [GO:0015087]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; magnesium ion transmembrane transporter activity [GO:0015095]; cobalt ion transport [GO:0006824]; magnesium ion transmembrane transport [GO:1903830]; protein homooligomerization [GO:0051260]	cobalt ion transport [GO:0006824]; magnesium ion transmembrane transport [GO:1903830]; protein homooligomerization [GO:0051260]	cobalt ion transport [GO:0006824]; magnesium ion transmembrane transport [GO:1903830]; protein homooligomerization [GO:0051260]	integral component of plasma membrane [GO:0005887]	integral component of plasma membrane [GO:0005887]	cobalt ion binding [GO:0050897]; cobalt ion transmembrane transporter activity [GO:0015087]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; magnesium ion transmembrane transporter activity [GO:0015095]	cobalt ion binding [GO:0050897]; cobalt ion transmembrane transporter activity [GO:0015087]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; magnesium ion transmembrane transporter activity [GO:0015095]
d2bbqa__d4xscd___1			Proteobacteria		cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytosol [GO:0005829]		magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d2bbvb__d1f8v.1__1					T=3 icosahedral viral capsid [GO:0039617]; aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]	T=3 icosahedral viral capsid [GO:0039617]; aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]		permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]
d2bc4a2_d5uslc1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; MHC class II protein complex binding [GO:0023026]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]	integral component of membrane [GO:0016021]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]		integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	integral component of membrane [GO:0016021]	MHC class II protein complex binding [GO:0023026]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2bc4b2_d3inun1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; MHC class II protein complex binding [GO:0023026]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]		integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]		MHC class II protein complex binding [GO:0023026]	
d2bc4c2_d3tvmf___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; MHC class II protein complex binding [GO:0023026]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	MHC class II protein complex binding [GO:0023026]	
d2bc4c2_d5j1aa2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; MHC class II protein complex binding [GO:0023026]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	MHC class II protein complex binding [GO:0023026]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2bc4d1_d1d9kg2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; MHC class II protein complex binding [GO:0023026]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]	adaptive immune response [GO:0002250]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	T cell receptor complex [GO:0042101]	MHC class II protein complex binding [GO:0023026]	
d2bc4d1_d4z7wc1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; MHC class II protein complex binding [GO:0023026]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]	nutrient reservoir activity [GO:0045735]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]		integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]		MHC class II protein complex binding [GO:0023026]	nutrient reservoir activity [GO:0045735]
d2bc4d2_d1py9a___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; MHC class II protein complex binding [GO:0023026]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; MHC class II protein complex assembly [GO:0002399]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell proliferation [GO:0042102]	cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]	MHC class II protein complex binding [GO:0023026]	signaling receptor binding [GO:0005102]
d2bc5c__d4cjga___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2bc5d__d1mqva___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2bcca1_d3l75o2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d2bcca2_d3l75b1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d2bccb1_d1sqbb2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d2bcgg3_d3zmua3__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cytoplasm [GO:0005737]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2bcka1_d3bz4a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2bcke2_d1rz7l1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2bcnc__d6coxb1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d2bcqa1_d4qzia1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2bcqa3_d9icja4__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d2bcra1_d4qzfa1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2bcwa1_d2qbci2__1			Proteobacteria		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; large ribosomal subunit [GO:0015934]; protein homodimerization activity [GO:0042803]; ribosome binding [GO:0043022]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; large ribosomal subunit [GO:0015934]		protein homodimerization activity [GO:0042803]; ribosome binding [GO:0043022]; structural constituent of ribosome [GO:0003735]	
d2bd5a__d3zvda1__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2bdaa__d4mdsa1__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2bdca__d1o2la___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2bdca__d5wq2a1__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	cysteine-type endopeptidase activity [GO:0004197]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]
d2bdgb__d3bsqa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2bdgb__d5a0ca___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; phagocytic vesicle [GO:0045335]; secretory granule [GO:0030141]; specific granule lumen [GO:0035580]; transcriptional repressor complex [GO:0017053]; cytokine binding [GO:0019955]; endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; transcription corepressor activity [GO:0003714]; acute inflammatory response to antigenic stimulus [GO:0002438]; antimicrobial humoral response [GO:0019730]; biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0002812]; cellular calcium ion homeostasis [GO:0006874]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of chemotaxis [GO:0050922]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of fungus [GO:0070947]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of immune response [GO:0050778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; response to UV [GO:0009411]; response to yeast [GO:0001878]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	acute inflammatory response to antigenic stimulus [GO:0002438]; antimicrobial humoral response [GO:0019730]; biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0002812]; cellular calcium ion homeostasis [GO:0006874]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of chemotaxis [GO:0050922]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of fungus [GO:0070947]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of immune response [GO:0050778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; response to UV [GO:0009411]; response to yeast [GO:0001878]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; phagocytic vesicle [GO:0045335]; secretory granule [GO:0030141]; specific granule lumen [GO:0035580]; transcriptional repressor complex [GO:0017053]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	cytokine binding [GO:0019955]; endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; transcription corepressor activity [GO:0003714]
d2bdha__d2qxia___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2bdha__d4cbob___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2bdhb__d1ossa___1	Metazoa		Chordata	Actinobacteria	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	serine-type endopeptidase activity [GO:0004252]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]		extracellular region [GO:0005576]; secretory granule [GO:0030141]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase activity [GO:0004252]
d2bdhc__d2by8x___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2bdil__d3mmga___1	Metazoa		Chordata		extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	helical viral capsid [GO:0019029]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]; RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	helical viral capsid [GO:0019029]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]
d2bdio__d1ghza___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2bdma2_d2ij3a___1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum membrane [GO:0005789]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]			endoplasmic reticulum membrane [GO:0005789]	cytoplasm [GO:0005737]	aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d2bdnh1_d4nhuc1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR2 chemokine receptor binding [GO:0031727]; chemokine activity [GO:0008009]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; astrocyte cell migration [GO:0043615]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular homeostasis [GO:0019725]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; helper T cell extravasation [GO:0035684]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of natural killer cell chemotaxis [GO:2000502]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of calcium ion import [GO:0090280]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of T cell activation [GO:0050870]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; viral genome replication [GO:0019079]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; astrocyte cell migration [GO:0043615]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular homeostasis [GO:0019725]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; helper T cell extravasation [GO:0035684]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of natural killer cell chemotaxis [GO:2000502]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of calcium ion import [GO:0090280]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of T cell activation [GO:0050870]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; viral genome replication [GO:0019079]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	CCR2 chemokine receptor binding [GO:0031727]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]	
d2bdzb__d3ieja1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	cysteine-type peptidase activity [GO:0008234]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d2bdzc__d5n9tb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]	chromosome [GO:0005694]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase activity [GO:0004197]; Lys48-specific deubiquitinase activity [GO:1990380]; p53 binding [GO:0002039]; protein C-terminus binding [GO:0008022]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitinyl hydrolase activity [GO:0101005]; histone H2B conserved C-terminal lysine deubiquitination [GO:0035616]; maintenance of DNA methylation [GO:0010216]; monoubiquitinated protein deubiquitination [GO:0035520]; multicellular organism development [GO:0007275]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of DNA demethylation [GO:1901537]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of protein stability [GO:0031647]; regulation of telomere capping [GO:1904353]; rhythmic process [GO:0048511]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]		histone H2B conserved C-terminal lysine deubiquitination [GO:0035616]; maintenance of DNA methylation [GO:0010216]; monoubiquitinated protein deubiquitination [GO:0035520]; multicellular organism development [GO:0007275]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of DNA demethylation [GO:1901537]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of protein stability [GO:0031647]; regulation of telomere capping [GO:1904353]; rhythmic process [GO:0048511]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	extracellular region [GO:0005576]	chromosome [GO:0005694]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]	cysteine-type peptidase activity [GO:0008234]	cysteine-type endopeptidase activity [GO:0004197]; Lys48-specific deubiquitinase activity [GO:1990380]; p53 binding [GO:0002039]; protein C-terminus binding [GO:0008022]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitinyl hydrolase activity [GO:0101005]
d2be5p3_d4oiof1__1			Deinococcus-Thermus	Deinococcus-Thermus	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]			DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d2be7b2_d2otci1__1			Proteobacteria	Proteobacteria	aspartate carbamoyltransferase complex [GO:0009347]; metal ion binding [GO:0046872]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	aspartate carbamoyltransferase complex [GO:0009347]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]
d2be7c2_d3e2pk2__1			Proteobacteria	Euryarchaeota	aspartate carbamoyltransferase complex [GO:0009347]; metal ion binding [GO:0046872]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	aspartate carbamoyltransferase complex [GO:0009347]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	metal ion binding [GO:0046872]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d2beda__d1tnze___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d2befa__d3fbfe1__1					cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2befc__d1nsko___1		Metazoa		Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]
d2bekc__d2gj9d___1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]; chromosome segregation [GO:0007059]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; chaperone-mediated protein folding [GO:0061077]; response to pH [GO:0009268]; tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]	chromosome segregation [GO:0007059]	chaperone-mediated protein folding [GO:0061077]; response to pH [GO:0009268]; tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]
d2belb__d1t26a1__1	Metazoa		Chordata	Apicomplexa	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	L-lactate dehydrogenase activity [GO:0004459]
d2beld1_d2x22b___1	Metazoa		Chordata	Actinobacteria	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d2bema__d1owrm1__1		Metazoa	Proteobacteria	Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]		B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]		chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d2bepa1_d2oxqa1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; filopodium tip [GO:0032433]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-ubiquitin ligase activity [GO:0034450]; cellular response to interferon-beta [GO:0035458]; free ubiquitin chain polymerization [GO:0010994]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein K48-linked ubiquitination [GO:0070936]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]	cytoplasm [GO:0005737]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; SMAD binding [GO:0046332]; TPR domain binding [GO:0030911]; ubiquitin-protein transferase activity [GO:0004842]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of glucocorticoid metabolic process [GO:0031943]; ubiquitin-dependent SMAD protein catabolic process [GO:0030579]	cellular response to interferon-beta [GO:0035458]; free ubiquitin chain polymerization [GO:0010994]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein K48-linked ubiquitination [GO:0070936]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of glucocorticoid metabolic process [GO:0031943]; ubiquitin-dependent SMAD protein catabolic process [GO:0030579]	cell [GO:0005623]; cytoplasm [GO:0005737]; filopodium tip [GO:0032433]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-ubiquitin ligase activity [GO:0034450]	Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; SMAD binding [GO:0046332]; TPR domain binding [GO:0030911]; ubiquitin-protein transferase activity [GO:0004842]
d2besd__d3k7sd___1			Actinobacteria		extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		ribose-5-phosphate isomerase activity [GO:0004751]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]
d2betb__d3sgwa___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		ribose-5-phosphate isomerase activity [GO:0004751]	isomerase activity [GO:0016853]
d2betc__d3m1pb___1			Actinobacteria		extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		ribose-5-phosphate isomerase activity [GO:0004751]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]
d2beub2_d3dvab2__1	Metazoa		Chordata	Firmicutes	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]		3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2bevb2_d1itza3__1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]
d2bewb2_d2qtcb3__1	Metazoa		Chordata	Proteobacteria	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	cytosol [GO:0005829]; membrane [GO:0016020]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]
d2bfbb1_d4ju8a1__1	Metazoa		Chordata	Proteobacteria	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	mandelate catabolic process [GO:0019596]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]		3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2bfbb2_d2c3ob3__1	Metazoa		Chordata	Proteobacteria	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	electron transport chain [GO:0022900]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	cytoplasm [GO:0005737]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d2bfcb2_d3dvaf2__1	Metazoa		Chordata	Firmicutes	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]		3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2bfcb2_d3exgj2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2bfeb1_d3dv0f1__1	Metazoa		Chordata	Firmicutes	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]		3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2bfga2_d5csua___1		Viridiplantae	Firmicutes	Streptophyta	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	amyloplast [GO:0009501]; chloroplast [GO:0009507]; 4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; glucose metabolic process [GO:0006006]; maltose catabolic process [GO:0000025]; starch catabolic process [GO:0005983]	xylan catabolic process [GO:0045493]	glucose metabolic process [GO:0006006]; maltose catabolic process [GO:0000025]; starch catabolic process [GO:0005983]		amyloplast [GO:0009501]; chloroplast [GO:0009507]	xylan 1,4-beta-xylosidase activity [GO:0009044]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]
d2bfgb2_d1jyvb5__1			Firmicutes	Proteobacteria	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	xylan 1,4-beta-xylosidase activity [GO:0009044]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2bfgc2_d1ghsa___1		Viridiplantae	Firmicutes	Streptophyta	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; (1->3)-beta-D-glucan catabolic process [GO:0006076]; defense response to fungus [GO:0050832]	xylan catabolic process [GO:0045493]	(1->3)-beta-D-glucan catabolic process [GO:0006076]; defense response to fungus [GO:0050832]			xylan 1,4-beta-xylosidase activity [GO:0009044]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]
d2bfgc2_d3wdpp1__1			Firmicutes	Euryarchaeota	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			xylan 1,4-beta-xylosidase activity [GO:0009044]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2bfgd2_d1v6ub2__1			Firmicutes	Actinobacteria	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			xylan 1,4-beta-xylosidase activity [GO:0009044]	endo-1,4-beta-xylanase activity [GO:0031176]
d2bfge2_d1z32x2__1		Metazoa	Firmicutes	Chordata	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]		extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	xylan 1,4-beta-xylosidase activity [GO:0009044]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d2bfgg2_d5i79a1__1		Fungi	Firmicutes	Ascomycota	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	xylan 1,4-beta-xylosidase activity [GO:0009044]	cellulase activity [GO:0008810]
d2bfgh2_d5brqd1__1			Firmicutes	Firmicutes	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]; alpha,alpha-phosphotrehalase activity [GO:0008788]; metal ion binding [GO:0046872]; trehalose catabolic process [GO:0005993]	xylan catabolic process [GO:0045493]	trehalose catabolic process [GO:0005993]		cytoplasm [GO:0005737]	xylan 1,4-beta-xylosidase activity [GO:0009044]	alpha,alpha-phosphotrehalase activity [GO:0008788]; metal ion binding [GO:0046872]
d2bfna__d1edba___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	response to toxic substance [GO:0009636]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	periplasmic space [GO:0042597]		haloalkane dehalogenase activity [GO:0018786]	haloalkane dehalogenase activity [GO:0018786]
d2bfqa__d5l9kb1__1			Euryarchaeota	Firmicutes	ADP-ribosylglutamate hydrolase activity [GO:0140293]; peptidyl-glutamate ADP-deribosylation [GO:0140291]	nucleotide binding [GO:0000166]	peptidyl-glutamate ADP-deribosylation [GO:0140291]				ADP-ribosylglutamate hydrolase activity [GO:0140293]	nucleotide binding [GO:0000166]
d2bfra__d3iida___1		Metazoa	Euryarchaeota	Chordata	ADP-ribosylglutamate hydrolase activity [GO:0140293]; peptidyl-glutamate ADP-deribosylation [GO:0140291]	Barr body [GO:0001740]; condensed chromosome [GO:0000793]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; sex chromatin [GO:0001739]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; enzyme binding [GO:0019899]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]; chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of response to oxidative stress [GO:1902883]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of response to oxidative stress [GO:1902884]; regulation of gene expression, epigenetic [GO:0040029]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	peptidyl-glutamate ADP-deribosylation [GO:0140291]	chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of response to oxidative stress [GO:1902883]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of response to oxidative stress [GO:1902884]; regulation of gene expression, epigenetic [GO:0040029]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]		Barr body [GO:0001740]; condensed chromosome [GO:0000793]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; sex chromatin [GO:0001739]	ADP-ribosylglutamate hydrolase activity [GO:0140293]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; enzyme binding [GO:0019899]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]
d2bful2_d1yc6b___1					host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	transport of virus in host, cell to cell [GO:0046740]		host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2bfus1_d1qju1___1					host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	transport of virus in host, cell to cell [GO:0046740]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2bgca2_d4z07e___1		Metazoa	Firmicutes	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	pathogenesis [GO:0009405]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]
d2bgce2_d5c8wa___1		Metazoa	Firmicutes	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; pathogenesis [GO:0009405]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; cofactor metabolic process [GO:0051186]; negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	pathogenesis [GO:0009405]	cofactor metabolic process [GO:0051186]; negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]		apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]
d2bgga2_d4g0ob___1		Viridiplantae	Euryarchaeota	Streptophyta	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; defense response, incompatible interaction [GO:0009814]; gene silencing by RNA [GO:0031047]; regulation of translation [GO:0006417]; response to virus [GO:0009615]; viral gene silencing in virus induced gene silencing [GO:0060145]		defense response, incompatible interaction [GO:0009814]; gene silencing by RNA [GO:0031047]; regulation of translation [GO:0006417]; response to virus [GO:0009615]; viral gene silencing in virus induced gene silencing [GO:0060145]		cytosol [GO:0005829]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2bgha1_d1xmda1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	vinorine synthase activity [GO:0050636]; alkaloid metabolic process [GO:0009820]	intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-octanoyltransferase activity [GO:0008458]; carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; response to drug [GO:0042493]	alkaloid metabolic process [GO:0009820]	carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; response to drug [GO:0042493]		intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	vinorine synthase activity [GO:0050636]	carnitine O-octanoyltransferase activity [GO:0008458]
d2bghb1_d1t7na1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	vinorine synthase activity [GO:0050636]; alkaloid metabolic process [GO:0009820]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	alkaloid metabolic process [GO:0009820]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]		endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	vinorine synthase activity [GO:0050636]	carnitine O-acetyltransferase activity [GO:0004092]
d2bgja1_d4c43a1__1			Proteobacteria	Cyanobacteria	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d2bgja2_d1quea2__1			Proteobacteria	Cyanobacteria	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d2bgjb2_d1qufa2__1			Proteobacteria	Cyanobacteria	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d2bgjc2_d5kswd2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]
d2bgjd1_d1ddgb1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]		cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]
d2bgjd1_d3ozwb2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]		response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2bgjd2_d1bqea2__1			Proteobacteria	Cyanobacteria	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d2bgna2_d1orva2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d2bgnb2_d2ix9a___1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]; cell wall macromolecule catabolic process [GO:0016998]; cellulose catabolic process [GO:0030245]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellulose catabolic process [GO:0030245]; cell wall macromolecule catabolic process [GO:0016998]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]
d2bgne1_d2adaa___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; in utero embryonic development [GO:0001701]; inosine biosynthetic process [GO:0046103]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]
d2bgne1_d2qeei1__1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	metal ion binding [GO:0046872]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	metal ion binding [GO:0046872]
d2bgra2_d5akla2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2bgwa1_d2mutb___1		Metazoa	Crenarchaeota	Chordata	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	chromosome, telomeric region [GO:0000781]; ERCC4-ERCC1 complex [GO:0070522]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 1 complex [GO:0000110]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]; damaged DNA binding [GO:0003684]; endodeoxyribonuclease activity [GO:0004520]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; single-stranded DNA binding [GO:0003697]; single-stranded DNA endodeoxyribonuclease activity [GO:0000014]; TFIID-class transcription factor complex binding [GO:0001094]; cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; global genome nucleotide-excision repair [GO:0070911]; interstrand cross-link repair [GO:0036297]; negative regulation of double-stranded telomeric DNA binding [GO:1905768]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance [GO:0032205]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of autophagy [GO:0010506]; resolution of meiotic recombination intermediates [GO:0000712]; response to UV [GO:0009411]; telomere maintenance [GO:0000723]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650]	DNA repair [GO:0006281]	cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; global genome nucleotide-excision repair [GO:0070911]; interstrand cross-link repair [GO:0036297]; negative regulation of double-stranded telomeric DNA binding [GO:1905768]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance [GO:0032205]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; regulation of autophagy [GO:0010506]; resolution of meiotic recombination intermediates [GO:0000712]; response to UV [GO:0009411]; telomere maintenance [GO:0000723]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650]		chromosome, telomeric region [GO:0000781]; ERCC4-ERCC1 complex [GO:0070522]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 1 complex [GO:0000110]; nucleus [GO:0005634]; transcription factor TFIID complex [GO:0005669]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; endodeoxyribonuclease activity [GO:0004520]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; single-stranded DNA binding [GO:0003697]; single-stranded DNA endodeoxyribonuclease activity [GO:0000014]; TFIID-class transcription factor complex binding [GO:0001094]
d2bh1a1_d4h5wa2__1		Metazoa	Proteobacteria	Chordata	Gram-negative-bacterium-type cell wall [GO:0009276]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type II protein secretion system complex [GO:0015627]; protein secretion [GO:0009306]; protein secretion by the type II secretion system [GO:0015628]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	protein secretion [GO:0009306]; protein secretion by the type II secretion system [GO:0015628]	ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	Gram-negative-bacterium-type cell wall [GO:0009276]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type II protein secretion system complex [GO:0015627]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d2bh1a2_d3ldqa1__1		Metazoa	Proteobacteria	Chordata	Gram-negative-bacterium-type cell wall [GO:0009276]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type II protein secretion system complex [GO:0015627]; protein secretion [GO:0009306]; protein secretion by the type II secretion system [GO:0015628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	protein secretion [GO:0009306]; protein secretion by the type II secretion system [GO:0015628]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	Gram-negative-bacterium-type cell wall [GO:0009276]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type II protein secretion system complex [GO:0015627]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d2bh1b1_d2i7na2__1		Metazoa	Proteobacteria	Chordata	Gram-negative-bacterium-type cell wall [GO:0009276]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type II protein secretion system complex [GO:0015627]; protein secretion [GO:0009306]; protein secretion by the type II secretion system [GO:0015628]	cell periphery [GO:0071944]; clathrin coat [GO:0030118]; cytosol [GO:0005829]; nucleus [GO:0005634]; recycling endosome [GO:0055037]; acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; coenzyme A biosynthetic process [GO:0015937]; coenzyme biosynthetic process [GO:0009108]	protein secretion [GO:0009306]; protein secretion by the type II secretion system [GO:0015628]	coenzyme A biosynthetic process [GO:0015937]; coenzyme biosynthetic process [GO:0009108]	Gram-negative-bacterium-type cell wall [GO:0009276]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type II protein secretion system complex [GO:0015627]	cell periphery [GO:0071944]; clathrin coat [GO:0030118]; cytosol [GO:0005829]; nucleus [GO:0005634]; recycling endosome [GO:0055037]		acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]
d2bh1b2_d1u6zb3__1			Proteobacteria	Proteobacteria	Gram-negative-bacterium-type cell wall [GO:0009276]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type II protein secretion system complex [GO:0015627]; protein secretion [GO:0009306]; protein secretion by the type II secretion system [GO:0015628]	plasma membrane [GO:0005886]; exopolyphosphatase activity [GO:0004309]; identical protein binding [GO:0042802]; phosphorus metabolic process [GO:0006793]; polyphosphate catabolic process [GO:0006798]	protein secretion [GO:0009306]; protein secretion by the type II secretion system [GO:0015628]	phosphorus metabolic process [GO:0006793]; polyphosphate catabolic process [GO:0006798]	Gram-negative-bacterium-type cell wall [GO:0009276]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type II protein secretion system complex [GO:0015627]	plasma membrane [GO:0005886]		exopolyphosphatase activity [GO:0004309]; identical protein binding [GO:0042802]
d2bh2b2_d1d2ha___1		Metazoa	Proteobacteria	Chordata	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; RNA binding [GO:0003723]; rRNA (uridine-C5-)-methyltransferase activity [GO:0070041]; rRNA base methylation [GO:0070475]	cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]; folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]	rRNA base methylation [GO:0070475]	folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052]		cytosol [GO:0005829]; methyltransferase complex [GO:0034708]; nucleus [GO:0005634]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; RNA binding [GO:0003723]; rRNA (uridine-C5-)-methyltransferase activity [GO:0070041]	folic acid binding [GO:0005542]; glycine binding [GO:0016594]; glycine N-methyltransferase activity [GO:0017174]; identical protein binding [GO:0042802]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d2bh7a2_d4fnnc___1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; outer membrane [GO:0019867]; N-acetyl-anhydromuramoyl-L-alanine amidase activity [GO:0009392]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; zinc ion binding [GO:0008270]; cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]; peptidoglycan turnover [GO:0009254]	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]; peptidoglycan turnover [GO:0009254]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cell outer membrane [GO:0009279]; outer membrane [GO:0019867]	extracellular region [GO:0005576]	N-acetyl-anhydromuramoyl-L-alanine amidase activity [GO:0009392]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; zinc ion binding [GO:0008270]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]
d2bhda2_d2gg7a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]		protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]	cytosol [GO:0005829]	aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]
d2bhnb1_d1x2ia1__1			Crenarchaeota	Euryarchaeota	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; DNA repair [GO:0006281]	DNA repair [GO:0006281]	DNA repair [GO:0006281]			DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]
d2bhnd1_d1x2ib___1			Crenarchaeota	Euryarchaeota	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; DNA repair [GO:0006281]	DNA repair [GO:0006281]	DNA repair [GO:0006281]			DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]
d2bhpa__d4qyjf___1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]					nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2bhpb__d4zwlf___1			Deinococcus-Thermus	Firmicutes	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; glycine betaine biosynthetic process from choline [GO:0019285]		glycine betaine biosynthetic process from choline [GO:0019285]			nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2bhsb__d3cepb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	cysteine biosynthetic process from serine [GO:0006535]	tryptophan biosynthetic process [GO:0000162]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]
d2bhua1_d1bvzb1__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2bhua2_d3s5yb2__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	trehalose biosynthetic process [GO:0005992]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cytoplasm [GO:0005737]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d2bi1a__d1aiaa___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	L-serine biosynthetic process [GO:0006564]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d2bi5a__d1xeya___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	L-serine biosynthetic process [GO:0006564]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]
d2biba2_d1dd6a___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2biea1_d5ft4a___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]	cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]; selenocysteine lyase activity [GO:0009000]; sulfurtransferase activity [GO:0016783]; iron-sulfur cluster assembly [GO:0016226]; sulfur amino acid metabolic process [GO:0000096]	L-serine biosynthetic process [GO:0006564]	iron-sulfur cluster assembly [GO:0016226]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]		O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]	cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]; selenocysteine lyase activity [GO:0009000]; sulfurtransferase activity [GO:0016783]
d2bifa2_d2p77b___1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]	catalytic activity [GO:0003824]	fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]		cytosol [GO:0005829]		6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]	catalytic activity [GO:0003824]
d2biga__d2hoza___1			Firmicutes	Cyanobacteria	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	L-serine biosynthetic process [GO:0006564]	chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d2bima__d5lapb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d2bimb__d2o93l2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d2bimb__d3d0ab___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d2biux__d1awvd___1	Metazoa	Metazoa	Chordata	Chordata	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d2bivc1_d2bivc2__1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; PcG protein complex [GO:0031519]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; anatomical structure morphogenesis [GO:0009653]	nucleus [GO:0005634]; PcG protein complex [GO:0031519]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; anatomical structure morphogenesis [GO:0009653]	anatomical structure morphogenesis [GO:0009653]	anatomical structure morphogenesis [GO:0009653]	nucleus [GO:0005634]; PcG protein complex [GO:0031519]	nucleus [GO:0005634]; PcG protein complex [GO:0031519]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2biwa__d5kjab___1			Cyanobacteria	Cyanobacteria	all-trans-8'-apo-beta-carotenal 15,15'-oxygenase [GO:0102162]; carotenoid dioxygenase activity [GO:0010436]; metal ion binding [GO:0046872]; carotene catabolic process [GO:0016121]	all-trans-8'-apo-beta-carotenal 15,15'-oxygenase [GO:0102162]; carotenoid dioxygenase activity [GO:0010436]; metal ion binding [GO:0046872]; carotene catabolic process [GO:0016121]	carotene catabolic process [GO:0016121]	carotene catabolic process [GO:0016121]			all-trans-8'-apo-beta-carotenal 15,15'-oxygenase [GO:0102162]; carotenoid dioxygenase activity [GO:0010436]; metal ion binding [GO:0046872]	all-trans-8'-apo-beta-carotenal 15,15'-oxygenase [GO:0102162]; carotenoid dioxygenase activity [GO:0010436]; metal ion binding [GO:0046872]
d2bj1b2_d2wvdc2__1			Euryarchaeota	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nickel cation binding [GO:0016151]; response to nickel cation [GO:0010045]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	response to nickel cation [GO:0010045]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]		protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nickel cation binding [GO:0016151]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2bj8b2_d3dhwc2__1			Euryarchaeota	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nickel cation binding [GO:0016151]; response to nickel cation [GO:0010045]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; Gram-negative-bacterium-type cell wall [GO:0009276]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATPase-coupled transmembrane transporter activity [GO:0042626]; D-methionine transmembrane transporter activity [GO:0048474]; L-methionine transmembrane transporter activity [GO:0015191]; D-methionine transport [GO:0048473]	response to nickel cation [GO:0010045]	D-methionine transport [GO:0048473]		ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; Gram-negative-bacterium-type cell wall [GO:0009276]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nickel cation binding [GO:0016151]	ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; D-methionine transmembrane transporter activity [GO:0048474]; L-methionine transmembrane transporter activity [GO:0015191]
d2bjec__d3mzib___1			Crenarchaeota	Cyanobacteria	acylphosphatase activity [GO:0003998]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]					acylphosphatase activity [GO:0003998]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]
d2bjjx1_d3a3ua___1	Metazoa		Chordata	Deinococcus-Thermus	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	carbon-carbon lyase activity [GO:0016830]; menaquinone biosynthetic process [GO:0009234]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	menaquinone biosynthetic process [GO:0009234]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	carbon-carbon lyase activity [GO:0016830]
d2bjjx2_d4io6b1__1	Metazoa	Metazoa	Chordata	Rotifera (rotifers)	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	integral component of membrane [GO:0016021]; G protein-coupled receptor activity [GO:0004930]; ligand-gated ion channel activity [GO:0015276]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]	G protein-coupled receptor activity [GO:0004930]; ligand-gated ion channel activity [GO:0015276]
d2bjoa__d1nyed1__1			Firmicutes	Proteobacteria	response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; hyperosmotic response [GO:0006972]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	response to oxidative stress [GO:0006979]	hyperosmotic response [GO:0006972]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]		peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2bjxa__d1we0h___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; procollagen-proline 4-dioxygenase complex [GO:0016222]; enzyme binding [GO:0019899]; integrin binding [GO:0005178]; peptide disulfide oxidoreductase activity [GO:0015037]; procollagen-proline 4-dioxygenase activity [GO:0004656]; protein disulfide isomerase activity [GO:0003756]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-7 [GO:0098761]; chylomicron assembly [GO:0034378]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; protein folding [GO:0006457]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976]; very-low-density lipoprotein particle assembly [GO:0034379]	cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-7 [GO:0098761]; chylomicron assembly [GO:0034378]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; protein folding [GO:0006457]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976]; very-low-density lipoprotein particle assembly [GO:0034379]	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; procollagen-proline 4-dioxygenase complex [GO:0016222]	cell [GO:0005623]; cytoplasm [GO:0005737]	enzyme binding [GO:0019899]; integrin binding [GO:0005178]; peptide disulfide oxidoreductase activity [GO:0015037]; procollagen-proline 4-dioxygenase activity [GO:0004656]; protein disulfide isomerase activity [GO:0003756]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2bjyb__d2pybb___1			Firmicutes	Spirochaetes	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d2bjyc__d3ajqa___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2bjyd__d3a9qu___1		Viridiplantae	Firmicutes	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2bjyf__d4xksd___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2bjyg__d5hjhd___1			Firmicutes	Cyanobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2bjyh__d4tobh___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2bjyh__d4toha___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2bjyi__d2v2sa___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2bjyl__d1ji4g___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2bk0a1_d3tvra1__1	Viridiplantae		Streptophyta	Actinobacteria	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]				abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	
d2bk4a2_d1iusa2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d2bk4b2_d1iuua2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d2bk6b__d2jd8l___1			Firmicutes	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d2bk6d__d1jiga___1			Firmicutes	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2bk6d__d5d8oi___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2bk7b1_d2bo9b2__1		Metazoa		Chordata		extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; histone acetylation [GO:0016573]; proteolysis [GO:0006508]		histone acetylation [GO:0016573]; proteolysis [GO:0006508]		extracellular space [GO:0005615]		metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2bk7b1_d3ksee___1		Metazoa		Chordata		cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]		cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]
d2bk7b2_d2bk7d2__1												
d2bk7d1_d2w9pj___1		Viridiplantae		Streptophyta		cysteine-type endopeptidase inhibitor activity [GO:0004869]						cysteine-type endopeptidase inhibitor activity [GO:0004869]
d2bk9a__d1y4qa___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]; oxygen transport [GO:0015671]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxygen transport [GO:0015671]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2bkba1_d6elka1__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	removal of superoxide radicals [GO:0019430]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]
d2bkba2_d1rfwa2__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	
d2bkba2_d4f2ng2__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	mitochondrion [GO:0005739]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2bkbb2_d4x9qa2__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	removal of superoxide radicals [GO:0019430]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]
d2bkbd1_d1pl4c1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2bkbd2_d3mdsb2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2bkbd2_d4br6a2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2bkca1_d1jqca___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2bkcd__d3qd8n1__1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2bkcg__d4m32c___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2bkch__d3qb9d___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2bkci__d1afrd___1		Viridiplantae	Firmicutes	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]; cytoplasm [GO:0005737]	chloroplast [GO:0009507]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d2bkci__d1uvhd___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2bkck__d5d8oe___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2bkcl__d1tk6b___1			Firmicutes	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d2bkcm__d4toem___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2bkcn__d3hx2l___1			Firmicutes		cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	
d2bkco__d1xvfc___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2bkcq__d1nfvo___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2bkcr__d3vpmb1__1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2bkcs__d3pwqg1__1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cellular iron ion homeostasis [GO:0006879]	phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytosol [GO:0005829]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	
d2bkcu__d1nfve___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2bkfa1_d2eela1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; M band [GO:0031430]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; phagophore assembly site [GO:0000407]; mitogen-activated protein kinase binding [GO:0051019]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270]; macroautophagy [GO:0016236]; negative regulation of osteoblast differentiation [GO:0045668]; protein complex oligomerization [GO:0051259]; regulation of bone mineralization [GO:0030500]; regulation of stress-activated MAPK cascade [GO:0032872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; mitochondrial envelope [GO:0005740]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein homodimerization activity [GO:0042803]; apoptotic process [GO:0006915]; cell death [GO:0008219]; lipid droplet organization [GO:0034389]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of sequestering of triglyceride [GO:0010890]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to stilbenoid [GO:0035634]; temperature homeostasis [GO:0001659]	macroautophagy [GO:0016236]; negative regulation of osteoblast differentiation [GO:0045668]; protein complex oligomerization [GO:0051259]; regulation of bone mineralization [GO:0030500]; regulation of stress-activated MAPK cascade [GO:0032872]	apoptotic process [GO:0006915]; cell death [GO:0008219]; lipid droplet organization [GO:0034389]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of sequestering of triglyceride [GO:0010890]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to stilbenoid [GO:0035634]; temperature homeostasis [GO:0001659]	autophagosome [GO:0005776]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; M band [GO:0031430]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; phagophore assembly site [GO:0000407]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; mitochondrial envelope [GO:0005740]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitogen-activated protein kinase binding [GO:0051019]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270]	protein homodimerization activity [GO:0042803]
d2bklb1_d1e5ta1__1		Metazoa	Proteobacteria	Chordata	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]				cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d2bklb2_d5t4ba2__1		Metazoa	Proteobacteria	Chordata	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2bkoa1_d4q25b___1			Euryarchaeota	Proteobacteria	cation transmembrane transporter activity [GO:0008324]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	cell [GO:0005623]; cytoplasm [GO:0005737]; protein homodimerization activity [GO:0042803]; cell chemotaxis [GO:0060326]; cellular phosphate ion homeostasis [GO:0030643]; negative regulation of chemotaxis [GO:0050922]; negative regulation of phosphate metabolic process [GO:0045936]; negative regulation of phosphate transmembrane transport [GO:2000186]; negative regulation of positive chemotaxis [GO:0050928]; phosphate ion transport [GO:0006817]	potassium ion transport [GO:0006813]	cell chemotaxis [GO:0060326]; cellular phosphate ion homeostasis [GO:0030643]; negative regulation of chemotaxis [GO:0050922]; negative regulation of phosphate metabolic process [GO:0045936]; negative regulation of phosphate transmembrane transport [GO:2000186]; negative regulation of positive chemotaxis [GO:0050928]; phosphate ion transport [GO:0006817]		cell [GO:0005623]; cytoplasm [GO:0005737]	cation transmembrane transporter activity [GO:0008324]; metal ion binding [GO:0046872]	protein homodimerization activity [GO:0042803]
d2bkua__d1sulb___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; disordered domain specific binding [GO:0097718]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]; mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore complex assembly [GO:0051292]; phosphatidylcholine biosynthetic process [GO:0006656]; protein import into nucleus [GO:0006606]; protein targeting to membrane [GO:0006612]; regulation of protein desumoylation [GO:0060188]	cytosol [GO:0005829]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; division septum assembly [GO:0000917]	mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore complex assembly [GO:0051292]; phosphatidylcholine biosynthetic process [GO:0006656]; protein import into nucleus [GO:0006606]; protein targeting to membrane [GO:0006612]; regulation of protein desumoylation [GO:0060188]	division septum assembly [GO:0000917]	cytoplasm [GO:0005737]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleus [GO:0005634]	cytosol [GO:0005829]	disordered domain specific binding [GO:0097718]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]
d2bkuc__d1xcpd1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; disordered domain specific binding [GO:0097718]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]; mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore complex assembly [GO:0051292]; phosphatidylcholine biosynthetic process [GO:0006656]; protein import into nucleus [GO:0006606]; protein targeting to membrane [GO:0006612]; regulation of protein desumoylation [GO:0060188]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore complex assembly [GO:0051292]; phosphatidylcholine biosynthetic process [GO:0006656]; protein import into nucleus [GO:0006606]; protein targeting to membrane [GO:0006612]; regulation of protein desumoylation [GO:0060188]	nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleus [GO:0005634]	molybdenum-iron nitrogenase complex [GO:0016612]	disordered domain specific binding [GO:0097718]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2bkzb2_d4cjyb1__1	Metazoa		Chordata		Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]		anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]		Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]		ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	
d2bl5a1_d3l7zc3__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; RNA binding [GO:0003723]; cell differentiation [GO:0030154]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; multicellular organism development [GO:0007275]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	cell differentiation [GO:0030154]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; multicellular organism development [GO:0007275]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	RNA binding [GO:0003723]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d2blha__d4q70a___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2blna1_d5uaia2__1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	cytosol [GO:0005829]; methionyl-tRNA formyltransferase activity [GO:0004479]; conversion of methionyl-tRNA to N-formyl-methionyl-tRNA [GO:0071951]; regulation of transmembrane transporter activity [GO:0022898]	lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA [GO:0071951]; regulation of transmembrane transporter activity [GO:0022898]		cytosol [GO:0005829]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]	methionyl-tRNA formyltransferase activity [GO:0004479]
d2blwa__d1a3b.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d2bm0a1_d3agjc5__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]		translational elongation [GO:0006414]		cytoplasm [GO:0005737]		GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]	
d2bm0a4_d1zm2c4__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	translational elongation [GO:0006414]		cytoplasm [GO:0005737]		GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d2bm1a1_d2rfkc___1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]	snoRNA binding [GO:0030515]; pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	translational elongation [GO:0006414]	pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	cytoplasm [GO:0005737]		GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]	snoRNA binding [GO:0030515]
d2bm1a4_d2zitc5__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	translational elongation [GO:0006414]		cytoplasm [GO:0005737]		GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d2bm1a5_d1n0vd5__1		Fungi	Deinococcus-Thermus	Ascomycota	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	translational elongation [GO:0006414]	maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]	GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]
d2bm1a5_d1zm3e4__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	translational elongation [GO:0006414]		cytoplasm [GO:0005737]		GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d2bm2d__d1ppge___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; phagocytic vesicle [GO:0045335]; secretory granule [GO:0030141]; specific granule lumen [GO:0035580]; transcriptional repressor complex [GO:0017053]; cytokine binding [GO:0019955]; endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; transcription corepressor activity [GO:0003714]; acute inflammatory response to antigenic stimulus [GO:0002438]; antimicrobial humoral response [GO:0019730]; biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0002812]; cellular calcium ion homeostasis [GO:0006874]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of chemotaxis [GO:0050922]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of fungus [GO:0070947]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of immune response [GO:0050778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; response to UV [GO:0009411]; response to yeast [GO:0001878]	proteolysis [GO:0006508]	acute inflammatory response to antigenic stimulus [GO:0002438]; antimicrobial humoral response [GO:0019730]; biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0002812]; cellular calcium ion homeostasis [GO:0006874]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of chemotaxis [GO:0050922]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of fungus [GO:0070947]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of immune response [GO:0050778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; response to UV [GO:0009411]; response to yeast [GO:0001878]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; phagocytic vesicle [GO:0045335]; secretory granule [GO:0030141]; specific granule lumen [GO:0035580]; transcriptional repressor complex [GO:0017053]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	cytokine binding [GO:0019955]; endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; transcription corepressor activity [GO:0003714]
d2bm2d__d5q0ga___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d2bm3a1_d2woba1__1			Firmicutes	Firmicutes	carbohydrate binding [GO:0030246]; polysaccharide catabolic process [GO:0000272]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2bm8e__d4p7gb___1		Metazoa	Actinobacteria	Chordata	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	lipid biosynthetic process [GO:0008610]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	methyltransferase activity [GO:0008168]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d2bm8f__d5x0zc___1			Actinobacteria	Proteobacteria	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	lipid biosynthetic process [GO:0008610]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]		cytosol [GO:0005829]	methyltransferase activity [GO:0008168]	spermidine synthase activity [GO:0004766]
d2bm8j__d3r0qc___1		Viridiplantae	Actinobacteria	Streptophyta	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; [myelin basic protein]-arginine N-methyltransferase activity [GO:0016277]; histone-arginine N-methyltransferase activity [GO:0008469]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; vegetative to reproductive phase transition of meristem [GO:0010228]	lipid biosynthetic process [GO:0008610]	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; vegetative to reproductive phase transition of meristem [GO:0010228]		cytosol [GO:0005829]	methyltransferase activity [GO:0008168]	[myelin basic protein]-arginine N-methyltransferase activity [GO:0016277]; histone-arginine N-methyltransferase activity [GO:0008469]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]
d2bm8l__d2br3a1__1			Actinobacteria	Actinobacteria	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	lipid biosynthetic process [GO:0008610]	lipid biosynthetic process [GO:0008610]			methyltransferase activity [GO:0008168]	methyltransferase activity [GO:0008168]
d2bm9b__d3p9ka2__1		Viridiplantae	Actinobacteria	Streptophyta	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	lipid biosynthetic process [GO:0008610]				methyltransferase activity [GO:0008168]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]
d2bm9d__d2br4d___1			Actinobacteria	Actinobacteria	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	lipid biosynthetic process [GO:0008610]	lipid biosynthetic process [GO:0008610]			methyltransferase activity [GO:0008168]	methyltransferase activity [GO:0008168]
d2bm9e__d4x7ub___1			Actinobacteria	Actinobacteria	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	magnesium ion binding [GO:0000287]; O-methyltransferase activity [GO:0008171]; antibiotic biosynthetic process [GO:0017000]; methylation [GO:0032259]	lipid biosynthetic process [GO:0008610]	antibiotic biosynthetic process [GO:0017000]; methylation [GO:0032259]			methyltransferase activity [GO:0008168]	magnesium ion binding [GO:0000287]; O-methyltransferase activity [GO:0008171]
d2bm9f__d2h11a___1		Metazoa	Actinobacteria	Chordata	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]; drug metabolic process [GO:0017144]; methylation [GO:0032259]; nucleobase-containing compound metabolic process [GO:0006139]	lipid biosynthetic process [GO:0008610]	drug metabolic process [GO:0017144]; methylation [GO:0032259]; nucleobase-containing compound metabolic process [GO:0006139]		cytosol [GO:0005829]	methyltransferase activity [GO:0008168]	S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]
d2bmha__d4aw3b___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]		aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2bmhb__d2l8ma___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2bmia__d5nggb___1			Bacteroidetes	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d2bmka2_d3utpl1__1												
d2bmkh1_d1t0na1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2bmkl1_d3cdgd1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2bmkl2_d1mfdl1__1												
d2bmoa2_d2xrxw2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; cellular metabolic process [GO:0044237]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2bmob1_d5xbpf___1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; cellular metabolic process [GO:0044237]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	cellular metabolic process [GO:0044237]	cellular metabolic process [GO:0044237]			2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]
d2bmqa1_d3l75e2__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; cellular metabolic process [GO:0044237]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	cellular metabolic process [GO:0044237]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d2bmqa2_d2xrxs2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; cellular metabolic process [GO:0044237]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2bmra2_d2yfja2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; cellular metabolic process [GO:0044237]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2bmwa2_d4y9rb3__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	phycobilisome [GO:0030089]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d2bmza__d3r50d___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d2bmza__d5tqzd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d2bn0a__d1j4tc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d2bn0b__d3r51b___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d2bnja1_d1fhla___1	Fungi	Fungi	Ascomycota	Ascomycota	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metabolic process [GO:0008152]	xylan catabolic process [GO:0045493]	metabolic process [GO:0008152]			endo-1,4-beta-xylanase activity [GO:0031176]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]
d2bnma1_d3jxbd___1			Actinobacteria		dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	DNA binding [GO:0003677]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]				dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]	DNA binding [GO:0003677]
d2bnma2_d4o9eb1__1			Actinobacteria	Firmicutes	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]				dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]	
d2bnoa1_d3g5gh___1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	DNA binding [GO:0003677]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]				dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]	DNA binding [GO:0003677]
d2bnqa1_d1u8na1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]			
d2bnqb2_d4hbcl1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]			
d2bnqe2_d1igtb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2bnrd1_d6fabl1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2bnrd2_d4ozga2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2bnre1_d1u3hf___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	adaptive immune response [GO:0002250]	cytoplasm [GO:0005737]	T cell receptor complex [GO:0042101]		
d2bnre1_d5ty6l1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]			
d2bnre2_d5f9ac1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]			
d2bnub1_d4jfzl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2bnyc__d1gavs___1					T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2bo0a1_d3qjub2__1			Proteobacteria	Deinococcus-Thermus	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	nitrogen compound metabolic process [GO:0006807]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2bo6a__d1fzwg___1			Bacteroidetes	Proteobacteria	identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]; mannosylglycerate biosynthetic process [GO:0051479]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	mannosylglycerate biosynthetic process [GO:0051479]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]			identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2bo8b__d3zlkb___1			Bacteroidetes	Proteobacteria	identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]; mannosylglycerate biosynthetic process [GO:0051479]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	mannosylglycerate biosynthetic process [GO:0051479]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]			identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2bo8d__d5ifya___1			Bacteroidetes	Proteobacteria	identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]; mannosylglycerate biosynthetic process [GO:0051479]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; extracellular polysaccharide biosynthetic process [GO:0045226]	mannosylglycerate biosynthetic process [GO:0051479]	extracellular polysaccharide biosynthetic process [GO:0045226]			identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]
d2bo8f__d1mp3b___1			Bacteroidetes	Proteobacteria	identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]; mannosylglycerate biosynthetic process [GO:0051479]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	mannosylglycerate biosynthetic process [GO:0051479]	extracellular polysaccharide biosynthetic process [GO:0045226]			identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2bo9a1_d2deaa___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; histone acetylation [GO:0016573]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	histone acetylation [GO:0016573]; proteolysis [GO:0006508]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]
d2bo9d1_d4n6v6___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; histone acetylation [GO:0016573]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; protease binding [GO:0002020]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]	histone acetylation [GO:0016573]; proteolysis [GO:0006508]	adult locomotory behavior [GO:0008344]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]	extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; protease binding [GO:0002020]; RNA binding [GO:0003723]
d2bo9d2_d2bo9d1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; histone acetylation [GO:0016573]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; histone acetylation [GO:0016573]; proteolysis [GO:0006508]	histone acetylation [GO:0016573]; proteolysis [GO:0006508]	histone acetylation [GO:0016573]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2bo9d2_d4mon.3__1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; histone acetylation [GO:0016573]; proteolysis [GO:0006508]		histone acetylation [GO:0016573]; proteolysis [GO:0006508]		extracellular space [GO:0005615]		metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	
d2boaa1_d1cpsa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; histone acetylation [GO:0016573]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	histone acetylation [GO:0016573]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2boaa2_d1ayea2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; histone acetylation [GO:0016573]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; vacuole [GO:0005773]; carboxypeptidase activity [GO:0004180]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; protein catabolic process in the vacuole [GO:0007039]; proteolysis [GO:0006508]	histone acetylation [GO:0016573]; proteolysis [GO:0006508]	protein catabolic process in the vacuole [GO:0007039]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; vacuole [GO:0005773]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	carboxypeptidase activity [GO:0004180]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2boba1_d4krmj___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2boba2_d1kn4l1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2bobb1_d4xnma1__1	Metazoa		Chordata	Negarnaviricota	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d2bocb2_d4wwie1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2booa__d2zhxi___1			Deinococcus-Thermus	Actinobacteria	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d2bosd__d2c5cd___1			Proteobacteria		extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		toxin activity [GO:0090729]
d2boya__d5umhb___1			Actinobacteria	Proteobacteria	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]; catechol-containing compound metabolic process [GO:0009712]	catechol 1,2-dioxygenase activity [GO:0018576]; ferric iron binding [GO:0008199]; catechol-containing compound catabolic process [GO:0019614]	catechol-containing compound metabolic process [GO:0009712]	catechol-containing compound catabolic process [GO:0019614]			catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]	catechol 1,2-dioxygenase activity [GO:0018576]; ferric iron binding [GO:0008199]
d2bp0a1_d3sbph2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	nitrogen compound metabolic process [GO:0006807]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]		membrane [GO:0016020]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d2bp0b2_d1kbwd1__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]		cell outer membrane [GO:0009279]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2bp2a__d1t37a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]
d2bp6a__d2jdua___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	single-species biofilm formation [GO:0044010]	single-species biofilm formation [GO:0044010]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2bp6c__d2wr9b___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2bp6d__d2xr4a1__1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	identical protein binding [GO:0042802]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]
d2bp7c__d4k9oa3__1			Proteobacteria	Proteobacteria	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2bp7e__d3dv0b1__1			Proteobacteria	Firmicutes	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]			3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2bp7e__d3exea1__1		Metazoa	Proteobacteria	Chordata	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2bp8a2_d3qpkb3__1		Fungi	Proteobacteria	Ascomycota	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	nitrogen compound metabolic process [GO:0006807]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2bp8b1_d1niaa1__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2bp8b1_d3t6wb1__1		Fungi	Proteobacteria	Basidiomycota	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	nitrogen compound metabolic process [GO:0006807]				copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2bp8b2_d2x88a3__1			Proteobacteria	Firmicutes	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	nitrogen compound metabolic process [GO:0006807]	sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2bp8b2_d3sbpe2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	nitrogen compound metabolic process [GO:0006807]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]		membrane [GO:0016020]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d2bpdb__d5k8ya1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	integral component of plasma membrane [GO:0005887]; carbohydrate binding [GO:0030246]; defense response to virus [GO:0051607]	cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	defense response to virus [GO:0051607]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d2bpeb1_d1h8ua___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; transport vesicle [GO:0030133]; carbohydrate binding [GO:0030246]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; heparin binding [GO:0008201]; defense response to bacterium [GO:0042742]; neutrophil degranulation [GO:0043312]	cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	defense response to bacterium [GO:0042742]; neutrophil degranulation [GO:0043312]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; transport vesicle [GO:0030133]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; heparin binding [GO:0008201]
d2bpia1_d1gn3b1__1			Apicomplexa	Actinobacteria	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2bpia2_d1b06f2__1			Apicomplexa	Crenarchaeota	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2bpja1_d5l6bs___1		Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2bplb4_d2df8a___1				Euryarchaeota		carbohydrate derivative binding [GO:0097367]; carbohydrate derivative metabolic process [GO:1901135]		carbohydrate derivative metabolic process [GO:1901135]				carbohydrate derivative binding [GO:0097367]
d2bplc4_d4wmjb___1		Metazoa		Arthropoda		glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]				glucose-6-phosphate isomerase activity [GO:0004347]
d2bpmb1_d4ii5d2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2bpmb2_d1d3ub1__1	Metazoa		Chordata	Euryarchaeota	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA-templated transcription, initiation [GO:0006352]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]		ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2bpmd1_d4eosb2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2bpra1_d4r5jc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein refolding [GO:0042026]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein refolding [GO:0042026]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; DNA replication [GO:0006260]; protein-containing complex assembly [GO:0065003]; protein-containing complex disassembly [GO:0032984]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; sigma factor antagonist activity [GO:0016989]; unfolded protein binding [GO:0051082]; zinc ion binding [GO:0008270]
d2bpva__d4rldb1__1		Metazoa		Arthropoda	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]
d2bpxa__d2avva___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2bpxb__d5p79a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2bpya__d5p4oa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2bpza__d4djpb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]
d2bpzb__d1lyw.1__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	collagen-containing extracellular matrix [GO:0062023]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane raft [GO:0045121]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; aspartic-type endopeptidase activity [GO:0004190]; aspartic-type peptidase activity [GO:0070001]; peptidase activity [GO:0008233]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; collagen catabolic process [GO:0030574]; lipoprotein catabolic process [GO:0042159]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of establishment of protein localization [GO:0070201]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; collagen catabolic process [GO:0030574]; lipoprotein catabolic process [GO:0042159]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of establishment of protein localization [GO:0070201]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	collagen-containing extracellular matrix [GO:0062023]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane raft [GO:0045121]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; aspartic-type peptidase activity [GO:0070001]; peptidase activity [GO:0008233]
d2bq0b__d3p1qa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; transcriptional repressor complex [GO:0017053]; vacuolar membrane [GO:0005774]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; cytoplasmic sequestering of protein [GO:0051220]; hippo signaling [GO:0035329]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of protein dephosphorylation [GO:0035308]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of catalytic activity [GO:0043085]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; protein heterooligomerization [GO:0051291]; protein targeting [GO:0006605]; regulation of mRNA stability [GO:0043488]; viral process [GO:0016032]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]; potassium ion leak channel activity [GO:0022841]; voltage-gated potassium channel activity [GO:0005249]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; stabilization of membrane potential [GO:0030322]	cytoplasmic sequestering of protein [GO:0051220]; hippo signaling [GO:0035329]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of protein dephosphorylation [GO:0035308]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of catalytic activity [GO:0043085]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; protein heterooligomerization [GO:0051291]; protein targeting [GO:0006605]; regulation of mRNA stability [GO:0043488]; viral process [GO:0016032]	potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; stabilization of membrane potential [GO:0030322]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; transcriptional repressor complex [GO:0017053]; vacuolar membrane [GO:0005774]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]	potassium ion leak channel activity [GO:0022841]; voltage-gated potassium channel activity [GO:0005249]
d2bq1i1_d4cmyh___1			Proteobacteria	Chlorobi	ribonucleoside-diphosphate reductase complex [GO:0005971]; ATP binding [GO:0005524]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytoplasm [GO:0005737]	ATP binding [GO:0005524]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]
d2bq1j1_d1qghc___1			Proteobacteria	Firmicutes	ribonucleoside-diphosphate reductase complex [GO:0005971]; ATP binding [GO:0005524]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytoplasm [GO:0005737]	ATP binding [GO:0005524]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2bq1j1_d3rn9a___1			Proteobacteria	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; ATP binding [GO:0005524]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular aromatic compound metabolic process [GO:0006725]	ribonucleoside-diphosphate reductase complex [GO:0005971]		ATP binding [GO:0005524]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d2bq3a1_d2uvwa1__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d2bq4b__d3ouea2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	metal ion binding [GO:0046872]	anaerobic respiration [GO:0009061]		periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2bq7b__d2este___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2bq8x__d4dhlb2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; riboflavin metabolic process [GO:0006771]	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; riboflavin metabolic process [GO:0006771]		cytosol [GO:0005829]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]	extracellular region [GO:0005576]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]
d2bq9b1_d1f8ba___1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2bq9b2_d2eeba1__1		Metazoa		Chordata		actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]		actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]		actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]		actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d2bq9b3_d1bglg3__1												
d2bq9b3_d4duxb1__1				Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2bq9c1_d4gezh___1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2bq9c3_d4yw7e___1				Proteobacteria		cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]		carbohydrate binding [GO:0030246]
d2bqaa__d4s0wa___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2bqca__d4w51a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2bqda__d1ndmc___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2bqea__d3gxra___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2bqea__d4hv2a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2bqga__d169lb___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2bqha__d1c65a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2bqha__d1dkka___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2bqia__d1l66a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2bqka__d4ttdb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2bqla__d1jj1a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2bqla__d222la___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2bqpb__d3b00a___1	Viridiplantae		Streptophyta	Thermotogae	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2bqva__d5e5kb___1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2bqvb__d5p1ia___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d2br2a2_d3b4tc2__1			Crenarchaeota	Actinobacteria	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	plasma membrane [GO:0005886]; 3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasmic exosome (RNase complex) [GO:0000177]	plasma membrane [GO:0005886]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d2br2b1_d2go3b2__1			Crenarchaeota	Aquificae	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	rRNA catabolic process [GO:0016075]	lipid A biosynthetic process [GO:0009245]	cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d2br2d2_d2c37k2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2br2j1_d1fwld1__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]	rRNA catabolic process [GO:0016075]	threonine biosynthetic process [GO:0009088]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]	3'-5'-exoribonuclease activity [GO:0000175]	ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]
d2br2l1_d3df1i1__1			Crenarchaeota		cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]		rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]	
d2br2l2_d2wp8b2__1		Fungi	Crenarchaeota	Ascomycota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; exosome (RNase complex) [GO:0000178]; mitochondrion [GO:0005739]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleus [GO:0005634]; 3'-5'-exoribonuclease activity [GO:0000175]; endonuclease activity [GO:0004519]; endoribonuclease activity [GO:0004521]; tRNA binding [GO:0000049]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; mRNA processing [GO:0006397]; ncRNA 3'-end processing [GO:0043628]; nonfunctional rRNA decay [GO:0070651]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; mRNA processing [GO:0006397]; ncRNA 3'-end processing [GO:0043628]; nonfunctional rRNA decay [GO:0070651]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]; exosome (RNase complex) [GO:0000178]; mitochondrion [GO:0005739]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleus [GO:0005634]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]; endonuclease activity [GO:0004519]; endoribonuclease activity [GO:0004521]; tRNA binding [GO:0000049]
d2br2m2_d3m85d2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2br2n1_d2z4mi1__1			Crenarchaeota		cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]		rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]	
d2br2n2_d3l7zd2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	rRNA catabolic process [GO:0016075]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d2br2p1_d1nhia1__1			Crenarchaeota	Proteobacteria	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	mismatch repair complex [GO:0032300]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	rRNA catabolic process [GO:0016075]	mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	cytoplasmic exosome (RNase complex) [GO:0000177]	mismatch repair complex [GO:0032300]	3'-5'-exoribonuclease activity [GO:0000175]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]
d2br2p2_d2c37a2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2br2p2_d2je6a2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	rRNA catabolic process [GO:0016075]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d2br2s2_d1oyrd2__1			Crenarchaeota	Firmicutes	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d2br2u2_d2pnzb2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2br2v1_d2i2ue1__1			Crenarchaeota		cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]		rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]	
d2br2v2_d2br2i2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2br2w2_d2po0b2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2br3a1_d1yfjc___1			Actinobacteria		methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	nucleic acid binding [GO:0003676]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA replication [GO:0006260]; restriction-modification system evasion by virus [GO:0099018]	lipid biosynthetic process [GO:0008610]	DNA replication [GO:0006260]; restriction-modification system evasion by virus [GO:0099018]			methyltransferase activity [GO:0008168]	nucleic acid binding [GO:0003676]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]
d2br3c__d4pcla___1			Actinobacteria		methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]		lipid biosynthetic process [GO:0008610]				methyltransferase activity [GO:0008168]	
d2br3d__d5wz1g___1			Actinobacteria		methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	lipid biosynthetic process [GO:0008610]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	methyltransferase activity [GO:0008168]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2br4a__d1fjxa___1			Actinobacteria	Proteobacteria	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	lipid biosynthetic process [GO:0008610]	DNA restriction-modification system [GO:0009307]			methyltransferase activity [GO:0008168]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d2br4a__d2bm8i___1			Actinobacteria	Actinobacteria	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	lipid biosynthetic process [GO:0008610]	lipid biosynthetic process [GO:0008610]			methyltransferase activity [GO:0008168]	methyltransferase activity [GO:0008168]
d2br4b__d5wz1f___1			Actinobacteria		methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	lipid biosynthetic process [GO:0008610]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	methyltransferase activity [GO:0008168]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2br5e__d3pt6a5__1		Metazoa	Actinobacteria	Chordata	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; heterochromatin [GO:0000792]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; chromatin binding [GO:0003682]; DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates [GO:0051718]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; methyl-CpG binding [GO:0008327]; methyltransferase activity [GO:0008168]; promoter-specific chromatin binding [GO:1990841]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular response to amino acid stimulus [GO:0071230]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chromatin organization [GO:0006325]; DNA hypermethylation [GO:0044026]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation on cytosine [GO:0032776]; DNA methylation on cytosine within a CG sequence [GO:0010424]; gene silencing [GO:0016458]; maintenance of DNA methylation [GO:0010216]; negative regulation of gene expression [GO:0010629]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular associated smooth muscle cell apoptotic process [GO:1905460]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; response to drug [GO:0042493]; S-adenosylmethionine metabolic process [GO:0046500]	lipid biosynthetic process [GO:0008610]	cellular response to amino acid stimulus [GO:0071230]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chromatin organization [GO:0006325]; DNA hypermethylation [GO:0044026]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation on cytosine [GO:0032776]; DNA methylation on cytosine within a CG sequence [GO:0010424]; gene silencing [GO:0016458]; maintenance of DNA methylation [GO:0010216]; negative regulation of gene expression [GO:0010629]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular associated smooth muscle cell apoptotic process [GO:1905460]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; response to drug [GO:0042493]; S-adenosylmethionine metabolic process [GO:0046500]		cytoplasm [GO:0005737]; heterochromatin [GO:0000792]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]	methyltransferase activity [GO:0008168]	chromatin binding [GO:0003682]; DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates [GO:0051718]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; methyl-CpG binding [GO:0008327]; methyltransferase activity [GO:0008168]; promoter-specific chromatin binding [GO:1990841]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2br7b__d3wtld1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2br9a__d3axyc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; central region of growth cone [GO:0090724]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; kinesin complex [GO:0005871]; melanosome [GO:0042470]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; calcium channel regulator activity [GO:0005246]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; MHC class II protein complex binding [GO:0023026]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; potassium channel regulator activity [GO:0015459]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; hippo signaling [GO:0035329]; hippocampus development [GO:0021766]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; negative regulation of calcium ion export across plasma membrane [GO:1905913]; negative regulation of calcium ion transmembrane transporter activity [GO:1901020]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of peptidyl-serine dephosphorylation [GO:1902309]; neuron migration [GO:0001764]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; protein localization to nucleus [GO:0034504]; protein targeting [GO:0006605]; regulation of cellular response to heat [GO:1900034]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of heart rate by hormone [GO:0003064]; regulation of membrane repolarization [GO:0060306]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of potassium ion transmembrane transporter activity [GO:1901016]; substantia nigra development [GO:0021762]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; phosphatidylethanolamine binding [GO:0008429]; cell differentiation [GO:0030154]; flower development [GO:0009908]; inflorescence development [GO:0010229]; regulation of flower development [GO:0009909]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; short-day photoperiodism [GO:0048572]; short-day photoperiodism, flowering [GO:0048575]	cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; hippocampus development [GO:0021766]; hippo signaling [GO:0035329]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; negative regulation of calcium ion export across plasma membrane [GO:1905913]; negative regulation of calcium ion transmembrane transporter activity [GO:1901020]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of peptidyl-serine dephosphorylation [GO:1902309]; neuron migration [GO:0001764]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; protein localization to nucleus [GO:0034504]; protein targeting [GO:0006605]; regulation of cellular response to heat [GO:1900034]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of heart rate by hormone [GO:0003064]; regulation of membrane repolarization [GO:0060306]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of potassium ion transmembrane transporter activity [GO:1901016]; substantia nigra development [GO:0021762]; viral process [GO:0016032]	cell differentiation [GO:0030154]; flower development [GO:0009908]; inflorescence development [GO:0010229]; regulation of flower development [GO:0009909]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; short-day photoperiodism [GO:0048572]; short-day photoperiodism, flowering [GO:0048575]	cell [GO:0005623]; central region of growth cone [GO:0090724]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; kinesin complex [GO:0005871]; melanosome [GO:0042470]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; calcium channel regulator activity [GO:0005246]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; MHC class II protein complex binding [GO:0023026]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; potassium channel regulator activity [GO:0015459]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	phosphatidylethanolamine binding [GO:0008429]
d2brea__d2ye9a___1	Fungi	Metazoa	Ascomycota	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d2brpa1_d3ew4a1__1			Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		cell wall [GO:0005618]; extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	
d2brpa3_d1nsxa1__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	carbohydrate metabolic process [GO:0005975]	galactose metabolic process [GO:0006012]	cell wall [GO:0005618]; extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d2brqb__d1gvia1__1	Metazoa		Chordata	Deinococcus-Thermus	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	carbohydrate metabolic process [GO:0005975]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	alpha-amylase activity [GO:0004556]; calcium ion binding [GO:0005509]
d2brrh1_d2gsgc___1			Proteobacteria		cell outer membrane [GO:0009279]; porin activity [GO:0015288]; ion transmembrane transport [GO:0034220]		ion transmembrane transport [GO:0034220]		cell outer membrane [GO:0009279]		porin activity [GO:0015288]	
d2brrx1_d3e3qs___1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; porin activity [GO:0015288]; ion transmembrane transport [GO:0034220]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	ion transmembrane transport [GO:0034220]	adaptive immune response [GO:0002250]	cell outer membrane [GO:0009279]	T cell receptor complex [GO:0042101]	porin activity [GO:0015288]	
d2brrx2_d2c1pl1__1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; porin activity [GO:0015288]; ion transmembrane transport [GO:0034220]	metal ion binding [GO:0046872]	ion transmembrane transport [GO:0034220]		cell outer membrane [GO:0009279]		porin activity [GO:0015288]	metal ion binding [GO:0046872]
d2brry1_d1s7xd1__1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; porin activity [GO:0015288]; ion transmembrane transport [GO:0034220]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	ion transmembrane transport [GO:0034220]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell outer membrane [GO:0009279]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	porin activity [GO:0015288]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2brsa__d2vrpb___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; transport vesicle [GO:0030133]; carbohydrate binding [GO:0030246]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; heparin binding [GO:0008201]; defense response to bacterium [GO:0042742]; neutrophil degranulation [GO:0043312]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	defense response to bacterium [GO:0042742]; neutrophil degranulation [GO:0043312]	regulation of cytokine activity [GO:0060300]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; transport vesicle [GO:0030133]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; heparin binding [GO:0008201]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d2brsb__d3g81b1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; transport vesicle [GO:0030133]; carbohydrate binding [GO:0030246]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; heparin binding [GO:0008201]; defense response to bacterium [GO:0042742]; neutrophil degranulation [GO:0043312]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	defense response to bacterium [GO:0042742]; neutrophil degranulation [GO:0043312]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; transport vesicle [GO:0030133]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; heparin binding [GO:0008201]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d2brsb__d3paqa2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; transport vesicle [GO:0030133]; carbohydrate binding [GO:0030246]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; heparin binding [GO:0008201]; defense response to bacterium [GO:0042742]; neutrophil degranulation [GO:0043312]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	defense response to bacterium [GO:0042742]; neutrophil degranulation [GO:0043312]	cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; transport vesicle [GO:0030133]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; heparin binding [GO:0008201]	metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]
d2brwa1_d1n7pa1__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d2bs1c__d1hdwc___1					T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]		regulation of translation [GO:0006417]		T=3 icosahedral viral capsid [GO:0039617]		identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	
d2bs2b1_d3vrbf2__1		Metazoa	Proteobacteria	Nematoda (roundworms)	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d2bs2d3_d1d4ca3__1			Proteobacteria	Proteobacteria	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	periplasmic space [GO:0042597]; fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; tricarboxylic acid cycle [GO:0006099]	respirasome [GO:0070469]	periplasmic space [GO:0042597]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]	fumarate reductase (menaquinone) [GO:0102040]; metal ion binding [GO:0046872]; succinate dehydrogenase activity [GO:0000104]
d2bs2e2_d1r7sb___1			Proteobacteria	Proteobacteria	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	tricarboxylic acid cycle [GO:0006099]		respirasome [GO:0070469]		2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2bs4b1_d2wu5j2__1			Proteobacteria	Proteobacteria	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	respirasome [GO:0070469]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d2bs4b2_d1qoca___1			Proteobacteria		respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]		respirasome [GO:0070469]		2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]	
d2bs4e2_d2w3rg1__1			Proteobacteria	Proteobacteria	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	tricarboxylic acid cycle [GO:0006099]		respirasome [GO:0070469]		2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d2bs9b2_d1e0xb___1			Firmicutes	Actinobacteria	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	xylan 1,4-beta-xylosidase activity [GO:0009044]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d2bs9c2_d3vd5c3__1			Firmicutes	Proteobacteria	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	xylan 1,4-beta-xylosidase activity [GO:0009044]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2bs9e2_d1avaa2__1		Viridiplantae	Firmicutes	Streptophyta	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]	xylan catabolic process [GO:0045493]				xylan 1,4-beta-xylosidase activity [GO:0009044]	alpha-amylase inhibitor activity [GO:0015066]; serine-type endopeptidase inhibitor activity [GO:0004867]
d2bs9f2_d2c7fb2__1			Firmicutes	Firmicutes	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	xylan catabolic process [GO:0045493]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]		cytoplasm [GO:0005737]	xylan 1,4-beta-xylosidase activity [GO:0009044]	alpha-L-arabinofuranosidase activity [GO:0046556]
d2bsaa1_d2vnha1__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d2bsaa2_d4c43a2__1			Cyanobacteria	Cyanobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	phycobilisome [GO:0030089]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d2bsda1_d1kkec2__1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	viral outer capsid [GO:0039624]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]	viral outer capsid [GO:0039624]		
d2bsdb1_d4iosh___1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]	virus tail, baseplate [GO:0098025]		
d2bsea__d2j1kl___1		Metazoa		Chordata	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	virus tail, baseplate [GO:0098025]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2bseb__d3n0ib___1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]	viral capsid [GO:0019028]		metal ion binding [GO:0046872]
d2bsec__d3f0yi___1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]	viral capsid [GO:0019028]		
d2bsed1_d1kfah1__1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		virus tail, baseplate [GO:0098025]			
d2bsef1_d5mp6l1__1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		virus tail, baseplate [GO:0098025]			
d2bsla__d4jicb___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d2bspa__d1o8ga___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	pectin catabolic process [GO:0045490]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]
d2bsqa1_d1v8pa___1			Proteobacteria	Crenarchaeota	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]; migration in host [GO:0044001]	exonuclease activity [GO:0004527]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]	migration in host [GO:0044001]				DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]	exonuclease activity [GO:0004527]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]
d2bsra1_d4xp4l2__1	Metazoa	Metazoa	Chordata	Arthropoda	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]; adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of plasma membrane [GO:0005887]; neuronal cell body membrane [GO:0032809]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]
d2bsrb2_d1nezh___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2bssa1_d2ajsl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2bssa1_d3wifb2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2bssa2_d1dlha2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d2bssb2_d2gtwd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2bsta1_d3lzfl2__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]
d2bstb2_d4jn1l1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2bsud3_d4z7vb1__1		Viridiplantae		Streptophyta		nutrient reservoir activity [GO:0045735]						nutrient reservoir activity [GO:0045735]
d2bsud4_d4rgnc1__1				Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d2bsya1_d3tsla___1					dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dUTP metabolic process [GO:0046080]	nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]		viral nucleocapsid [GO:0019013]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d2bsya2_d2d4na___1					dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dUTP metabolic process [GO:0046080]	nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]		viral nucleocapsid [GO:0019013]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d2bt0a__d3g7ba___1	Metazoa		Chordata	Firmicutes	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d2bt2a1_d1agrh___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; visual perception [GO:0007601]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; visual perception [GO:0007601]	adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; plasma membrane [GO:0005886]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d2bt2a1_d3cika1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; visual perception [GO:0007601]	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; visual perception [GO:0007601]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; plasma membrane [GO:0005886]	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]	calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]
d2bt4a__d1gtzd___1			Actinobacteria	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d2bt4b__d3n86x___1			Actinobacteria	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]		cytosol [GO:0005829]	3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d2bt4i__d4rc9a___1			Actinobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d2bt6b__d2bs3e2__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d2btma__d4jeqa___1			Firmicutes		cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2btot__d5gstb2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d2btvq2_d3j9sa2__1					virion [GO:0019012]; structural molecule activity [GO:0005198]	T=13 icosahedral viral capsid [GO:0039621]; viral envelope [GO:0019031]; viral intermediate capsid [GO:0039626]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]; fusion of virus membrane with host plasma membrane [GO:0019064]		fusion of virus membrane with host plasma membrane [GO:0019064]	virion [GO:0019012]	T=13 icosahedral viral capsid [GO:0039621]; viral envelope [GO:0019031]; viral intermediate capsid [GO:0039626]	structural molecule activity [GO:0005198]	host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d2btvt2_d1bvp22__1					virion [GO:0019012]; structural molecule activity [GO:0005198]	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]; host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]; fusion of virus membrane with host plasma membrane [GO:0019064]		fusion of virus membrane with host plasma membrane [GO:0019064]	virion [GO:0019012]	viral envelope [GO:0019031]; viral outer capsid [GO:0039624]	structural molecule activity [GO:0005198]	host cell surface receptor binding [GO:0046789]; structural molecule activity [GO:0005198]
d2btyc__d1b7bb___1			Thermotogae	Firmicutes	cytoplasm [GO:0005737]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]; arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]	ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]
d2bu8a1_d3tz2a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740]; cellular response to nutrient [GO:0031670]; cellular response to reactive oxygen species [GO:0034614]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrion [GO:0005739]; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity [GO:0047323]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	cellular response to nutrient [GO:0031670]; cellular response to reactive oxygen species [GO:0034614]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]	branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740]	[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity [GO:0047323]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]
d2buaa2_d5hkba___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]		dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	hydrolase activity [GO:0016787]
d2buab2_d1mx1e___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d2buac2_d2qoea2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2buad1_d2qoeb1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2buad2_d3o0da___1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]		dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	triglyceride lipase activity [GO:0004806]
d2buca2_d4jh0b2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2bucc2_d3g7nb___1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	triglyceride lipase activity [GO:0004806]; lipid metabolic process [GO:0006629]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	lipid metabolic process [GO:0006629]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]		dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	triglyceride lipase activity [GO:0004806]
d2bucd1_d4jh0b1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2bufg__d2x2wb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	cytoplasm [GO:0005737]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; cellular response to DNA damage stimulus [GO:0006974]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; cellular response to DNA damage stimulus [GO:0006974]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]	acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]
d2buhb1_d1oeqa3__1			Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	
d2buhd2_d3ov3a2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	flavonoid biosynthetic process [GO:0009813]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2buia1_d1z1ea2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2buia2_d1hnda1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2buib1_d4jrmc1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d2buib2_d4z8da1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2buic2_d3awka2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2buid2_d5bz4b2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2bumb__d1ykpg___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d2buna1_d2w4dc___1			Proteobacteria	Euryarchaeota	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]
d2buoa__d1d1da1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; viral budding via host ESCRT complex [GO:0039702]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]; aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral procapsid maturation [GO:0046797]	viral budding via host ESCRT complex [GO:0039702]	viral procapsid maturation [GO:0046797]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d2buoa__d3nteb2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; viral budding via host ESCRT complex [GO:0039702]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; ATP biosynthetic process [GO:0006754]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; viral budding via host ESCRT complex [GO:0039702]	viral budding via host ESCRT complex [GO:0039702]	ATP biosynthetic process [GO:0006754]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; viral budding via host ESCRT complex [GO:0039702]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; viral nucleocapsid [GO:0019013]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2bupa2_d5fpnb1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	blood microparticle [GO:0072562]; CatSper complex [GO:0036128]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; meiotic spindle [GO:0072687]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptonemal complex [GO:0000795]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; glycolipid binding [GO:0051861]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; tau protein binding [GO:0048156]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein phosphorylation [GO:0001934]; protein refolding [GO:0042026]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex disassembly [GO:0070194]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein phosphorylation [GO:0001934]; protein refolding [GO:0042026]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex disassembly [GO:0070194]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	blood microparticle [GO:0072562]; CatSper complex [GO:0036128]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; meiotic spindle [GO:0072687]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptonemal complex [GO:0000795]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; glycolipid binding [GO:0051861]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; tau protein binding [GO:0048156]; unfolded protein binding [GO:0051082]
d2burb__d3pcfb___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d2buxa1_d3pcnc___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d2bv0a__d3mv4b___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d2bv1b__d2ik8b1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; leukotriene signaling pathway [GO:0061737]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; protein folding [GO:0006457]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]; response to peptide hormone [GO:0043434]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; leukotriene signaling pathway [GO:0061737]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; protein folding [GO:0006457]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]; response to peptide hormone [GO:0043434]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	calmodulin binding [GO:0005516]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d2bv2a__d1zira1__1		Metazoa		Chordata		structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]
d2bv2b__d1prra2__1				Proteobacteria		metal ion binding [GO:0046872]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]				metal ion binding [GO:0046872]
d2bv3a1_d4rcza2__1			Deinococcus-Thermus	Crenarchaeota	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	translational elongation [GO:0006414]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d2bv3a3_d3wu3a___1			Deinococcus-Thermus		cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]		translational elongation [GO:0006414]		cytoplasm [GO:0005737]		GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]	
d2bv8k__d1hacb___1		Metazoa	Rhodophyta	Chordata	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2bvcc1_d4lnfe1__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d2bvcc2_d2glsf2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d2bvcd1_d1htqd1__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d2bvcd2_d1htoe2__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d2bvce1_d1f52k1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d2bvcf2_d1bg0a2__1		Metazoa	Actinobacteria	Arthropoda	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d2bvcf2_d3l2gc2__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	
d2bvea__d4x4yb___1	Metazoa		Chordata		extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]		cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]		extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]	
d2bveb__d1cfqa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2bvfa1_d1n62f2__1			Actinobacteria	Proteobacteria	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2bvga1_d5mxub1__1		Fungi	Actinobacteria	Ascomycota	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]		methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d2bvga2_d1dzna1__1		Fungi	Actinobacteria	Ascomycota	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]		methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d2bvgd2_d1e8ha1__1		Fungi	Actinobacteria	Ascomycota	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]		methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d2bvha2_d5fxfb1__1			Actinobacteria	Actinobacteria	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]					(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d2bvhb1_d5mxja2__1		Fungi	Actinobacteria	Ascomycota	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]		methanol metabolic process [GO:0015945]		peroxisome [GO:0005777]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d2bvhb2_d1jrpc4__1			Actinobacteria	Proteobacteria	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d2bvhd2_d1rm6b2__1			Actinobacteria	Proteobacteria	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]					(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]
d2bvig2_d1hx6b2__1						viral capsid [GO:0019028]; virion [GO:0019012]				viral capsid [GO:0019028]; virion [GO:0019012]		
d2bvik2_d1hx6c2__1						viral capsid [GO:0019028]; virion [GO:0019012]				viral capsid [GO:0019028]; virion [GO:0019012]		
d2bvio2_d1m3ya1__1												
d2bviq2_d1cjda2__1						viral capsid [GO:0019028]; virion [GO:0019012]				viral capsid [GO:0019028]; virion [GO:0019012]		
d2bvla1_d1o7oa___1		Metazoa	Firmicutes	Chordata	host cell plasma membrane [GO:0020002]; cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	host cell plasma membrane [GO:0020002]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d2bvna1_d1ttta1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2bvnb1_d2j28d1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]
d2bvnb2_d1ob5a2__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2bvoa1_d3u4eb1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d2bvob__d2d7th___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2bvpa1_d1mh5l1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2bvpb__d4evnn1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2bvqa1_d5vshb2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2bvqb__d1nbqa2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]; cadherin binding [GO:0045296]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618]; actomyosin structure organization [GO:0031032]; bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; establishment of endothelial intestinal barrier [GO:0090557]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to bicellular tight junction [GO:1902396]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of cytoskeleton organization [GO:0051493]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]; transforming growth factor beta receptor signaling pathway [GO:0007179]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actomyosin structure organization [GO:0031032]; bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; establishment of endothelial intestinal barrier [GO:0090557]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to bicellular tight junction [GO:1902396]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of cytoskeleton organization [GO:0051493]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]; transforming growth factor beta receptor signaling pathway [GO:0007179]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cadherin binding [GO:0045296]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618]
d2bvub__d2mspb___1	Metazoa	Metazoa	Nematoda (roundworms)	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]; identical protein binding [GO:0042802]			cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]		identical protein binding [GO:0042802]
d2bvwa__d1qk2b___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]
d2bvwb__d3a9aa___1	Fungi		Ascomycota		extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	
d2bvza1_d1fjgf___1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2bw1a__d2yjkh___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d2bw1d__d2ib0a1__1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	
d2bw6a__d3npsa___1		Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]		cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]		basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2bw7c1_d3r5gb___1			Cyanobacteria	Proteobacteria	adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; cyclic nucleotide biosynthetic process [GO:0009190]; protein-chromophore linkage [GO:0018298]	integral component of membrane [GO:0016021]; adenylate cyclase activity [GO:0004016]; cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556]; pathogenesis [GO:0009405]	cyclic nucleotide biosynthetic process [GO:0009190]; protein-chromophore linkage [GO:0018298]	cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556]; pathogenesis [GO:0009405]		integral component of membrane [GO:0016021]	adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]	adenylate cyclase activity [GO:0004016]
d2bwaa__d2xb6c___1		Metazoa	Bacteroidetes	Chordata	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	polysaccharide catabolic process [GO:0000272]	angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]		axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	cellulase activity [GO:0008810]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]
d2bwaa__d3vzla___1			Bacteroidetes	Firmicutes	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]			cellulase activity [GO:0008810]	endo-1,4-beta-xylanase activity [GO:0031176]
d2bwab__d1qotb___1		Viridiplantae	Bacteroidetes	Streptophyta	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	polysaccharide catabolic process [GO:0000272]				cellulase activity [GO:0008810]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2bwca__d1ukrd___1		Fungi	Bacteroidetes	Ascomycota	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	cellulase activity [GO:0008810]	endo-1,4-beta-xylanase activity [GO:0031176]
d2bwca__d1v6md___1		Viridiplantae	Bacteroidetes	Streptophyta	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	polysaccharide catabolic process [GO:0000272]				cellulase activity [GO:0008810]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2bwda2_d1kyaa1__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2bwia1_d3c75a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]; methylamine metabolic process [GO:0030416]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	methylamine metabolic process [GO:0030416]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]
d2bwjb__d2eyqb3__1	Metazoa		Chordata	Proteobacteria	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]	cytosol [GO:0005829]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]	cytosol [GO:0005829]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]
d2bwjd__d1kaoa___1	Metazoa	Metazoa	Chordata	Chordata	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]	cytosol [GO:0005829]; midbody [GO:0030496]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; actin cytoskeleton reorganization [GO:0031532]; cellular protein localization [GO:0034613]; cellular response to drug [GO:0035690]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to plasma membrane [GO:0072659]; Rap protein signal transduction [GO:0032486]; regulation of dendrite morphogenesis [GO:0048814]; regulation of JNK cascade [GO:0046328]	ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]	actin cytoskeleton reorganization [GO:0031532]; cellular protein localization [GO:0034613]; cellular response to drug [GO:0035690]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to plasma membrane [GO:0072659]; Rap protein signal transduction [GO:0032486]; regulation of dendrite morphogenesis [GO:0048814]; regulation of JNK cascade [GO:0046328]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]	cytosol [GO:0005829]; midbody [GO:0030496]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d2bwje__d1lfdb___1	Metazoa	Metazoa	Chordata	Chordata	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d2bwjf__d1ojlb___1	Metazoa		Chordata	Proteobacteria	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d2bwna1_d4wyfa___1			Proteobacteria	Actinobacteria	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	protoporphyrinogen IX biosynthetic process [GO:0006782]	biotin biosynthetic process [GO:0009102]		cytoplasm [GO:0005737]	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]
d2bwnb__d3aeoa___1			Proteobacteria		5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]; protoporphyrinogen IX biosynthetic process [GO:0006782]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	protoporphyrinogen IX biosynthetic process [GO:0006782]	transsulfuration [GO:0019346]			5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d2bwod__d4azja___1			Proteobacteria	Firmicutes	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]	protoporphyrinogen IX biosynthetic process [GO:0006782]	L-serine biosynthetic process [GO:0006564]		cytoplasm [GO:0005737]	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]
d2bwod__d4bq0c___1			Proteobacteria	Proteobacteria	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]; protoporphyrinogen IX biosynthetic process [GO:0006782]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]; beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	protoporphyrinogen IX biosynthetic process [GO:0006782]	beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]			5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]
d2bwpa__d5hdmb___1		Viridiplantae	Proteobacteria	Streptophyta	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]; protoporphyrinogen IX biosynthetic process [GO:0006782]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; plastid [GO:0009536]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	protoporphyrinogen IX biosynthetic process [GO:0006782]	chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]		apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; plastid [GO:0009536]	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d2bwpd__d1wyuh___1			Proteobacteria	Deinococcus-Thermus	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]; protoporphyrinogen IX biosynthetic process [GO:0006782]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	protoporphyrinogen IX biosynthetic process [GO:0006782]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]			5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]
d2bwua1_d1jawa1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]			cytosol [GO:0005829]	cytosol [GO:0005829]	aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]
d2bwxa2_d1wlra2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]			cytosol [GO:0005829]	cytosol [GO:0005829]	aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]
d2bx3a__d1mbmb___1					cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	host cell membrane [GO:0033644]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell membrane [GO:0033644]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2bx5a__d1flrl1__1	Metazoa	Metazoa	Chordata	Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2bx5c__d4pj7h2__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2bx5d__d1hezd1__1	Metazoa	Metazoa	Chordata	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2bx5e__d4m1di1__1	Metazoa		Chordata			host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d2bx5g__d4i3rl1__1	Metazoa		Chordata			host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d2bx5i__d4x7sl1__1	Metazoa		Chordata									
d2bx5n__d3tv3l2__1	Metazoa	Metazoa	Chordata	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2bx5o__d1i8lc___1	Metazoa	Metazoa	Chordata	Chordata		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]		
d2bx5o__d5u1rg1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2bx7a__d5k1ka___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; FMN binding [GO:0010181]; riboflavin reductase (NADPH) activity [GO:0042602]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]	cytosol [GO:0005829]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; riboflavin reductase (NADPH) activity [GO:0042602]
d2bx8a1_d4n0fd1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2bx8b1_d5ijea1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bx8b2_d3b9la3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxaa1_d3v03a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxab1_d1e7ia3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxab2_d4k71d1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2bxca3_d5orfc3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d2bxcb1_d2bxda3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxcb3_d2bxfa2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxda1_d1n5ua3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxdb1_d1lota2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2bxdb3_d1kw2a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]; vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]
d2bxea1_d5otba2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d2bxea2_d5id7b1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxeb1_d2vdba2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxfa1_d1j7eb3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]; vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	vitamin D metabolic process [GO:0042359]; vitamin transport [GO:0051180]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; calcidiol binding [GO:1902118]; vitamin D binding [GO:0005499]; vitamin transmembrane transporter activity [GO:0090482]
d2bxfa1_d3v08a3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxfa3_d1hk1a3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxfa3_d5otbd2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d2bxga2_d4l8ua1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxgb1_d5giya3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxha1_d2xvwa2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxhb1_d5hoza3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxhb2_d2bxhb3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxia2_d2bxpa2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxia2_d4luha1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d2bxia3_d1hk2a3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxka2_d1hk4a3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxla1_d5orfb3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d2bxla2_d4zbra2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxma1_d1e7ga1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxma1_d4or0b2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxna2_d4lufa2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d2bxoa1_d5dbya2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxoa3_d4bkea3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxpa1_d4l9kb3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxpa3_d3sqjb3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxqa2_d4emxa3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxqa3_d3b9ma1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2bxwb__d2eeda1__1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d2by0a2_d3l2ma2__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	trehalose biosynthetic process [GO:0005992]	carbohydrate catabolic process [GO:0016052]	cytoplasm [GO:0005737]	extracellular space [GO:0005615]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d2by3a2_d1cxia3__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2by6x__d2wv5b___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2by7x__d2o8la___1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; pathogenesis [GO:0009405]	digestion [GO:0007586]; proteolysis [GO:0006508]	pathogenesis [GO:0009405]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d2by9x__d2ouaa___1	Metazoa		Chordata	Actinobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d2byba2_d1b5qc2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]
d2bybb2_d1l9ea2__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	tetrahydrofolate metabolic process [GO:0046653]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	sarcosine oxidase activity [GO:0008115]
d2byca1_d1x0pj___1				Cyanobacteria		blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]						blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]
d2byga1_d4r2za1__1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; guanylate kinase activity [GO:0004385]; kinase binding [GO:0019900]; structural constituent of postsynaptic density [GO:0098919]; anterograde axonal protein transport [GO:0099641]; cell-cell adhesion [GO:0098609]; cellular response to potassium ion [GO:0035865]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; MAPK cascade [GO:0000165]; negative regulation of phosphatase activity [GO:0010923]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of NMDA receptor activity [GO:2000310]; retrograde axonal protein transport [GO:0099642]; sensory perception of pain [GO:0019233]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]; carnitine transport [GO:0015879]; in utero embryonic development [GO:0001701]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; protein localization to plasma membrane [GO:0072659]; regulation of anion transport [GO:0044070]	anterograde axonal protein transport [GO:0099641]; cell-cell adhesion [GO:0098609]; cellular response to potassium ion [GO:0035865]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; MAPK cascade [GO:0000165]; negative regulation of phosphatase activity [GO:0010923]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of NMDA receptor activity [GO:2000310]; retrograde axonal protein transport [GO:0099642]; sensory perception of pain [GO:0019233]	carnitine transport [GO:0015879]; in utero embryonic development [GO:0001701]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; protein localization to plasma membrane [GO:0072659]; regulation of anion transport [GO:0044070]	axon cytoplasm [GO:1904115]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]	guanylate kinase activity [GO:0004385]; kinase binding [GO:0019900]; structural constituent of postsynaptic density [GO:0098919]	PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]
d2byha__d4wuba1__1	Metazoa		Chordata	Proteobacteria	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; DNA-dependent ATPase activity [GO:0008094]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d2byja1_d5gvka___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]		ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d2bykb1_d1tafa___1	Metazoa	Metazoa	Arthropoda	Arthropoda	CHRAC [GO:0008623]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]; nucleosome mobilization [GO:0042766]	nucleus [GO:0005634]; SAGA complex [GO:0000124]; transcription factor TFIID complex [GO:0005669]; protein heterodimerization activity [GO:0046982]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; histone H3 acetylation [GO:0043966]; ovarian follicle cell development [GO:0030707]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	nucleosome mobilization [GO:0042766]	histone H3 acetylation [GO:0043966]; ovarian follicle cell development [GO:0030707]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	CHRAC [GO:0008623]	nucleus [GO:0005634]; SAGA complex [GO:0000124]; transcription factor TFIID complex [GO:0005669]	DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]	protein heterodimerization activity [GO:0046982]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2bykd__d3azle___1	Metazoa	Metazoa	Arthropoda	Chordata	CHRAC [GO:0008623]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]; nucleosome mobilization [GO:0042766]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleosome mobilization [GO:0042766]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	CHRAC [GO:0008623]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2bylb__d4lw2b1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]; selenocysteine lyase activity [GO:0009000]; sulfurtransferase activity [GO:0016783]; iron-sulfur cluster assembly [GO:0016226]; sulfur amino acid metabolic process [GO:0000096]	arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	iron-sulfur cluster assembly [GO:0016226]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]		ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]	cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]; selenocysteine lyase activity [GO:0009000]; sulfurtransferase activity [GO:0016783]
d2byre1_d2ymeb___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2byrf1_d3sq9c___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d2bywa1_d1m1ma1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d2bywa2_d1u0mb1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; melanin biosynthetic process [GO:0042438]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	melanin biosynthetic process [GO:0042438]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2bywb1_d1oxhd2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d2bywb2_d4yuca1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2bywc1_d2c9ha2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2byxb2_d1oxha1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d2byxc1_d3v4xa2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	isoprenoid biosynthetic process [GO:0008299]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d2byxd1_d4f32b2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d2byyb1_d3wd8c2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2byyb2_d2cdhe2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2byyc1_d5wx6c1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2byyc2_d2ebdb2__1			Proteobacteria	Aquificae	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2byyd1_d1m3zd1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2byyd1_d4jrmd2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d2byyd2_d2bz4d1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2byzb2_d2byza1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2byzd1_d5wx5b2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2bz2a1_d5iqqe___1	Metazoa	Metazoa	Chordata	Chordata	NELF complex [GO:0032021]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chromatin binding [GO:0003682]; RNA binding [GO:0003723]; negative regulation of mRNA polyadenylation [GO:1900364]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 14-3-3 protein binding [GO:0071889]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]; meiotic cell cycle [GO:0051321]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; snRNA catabolic process [GO:0016076]	negative regulation of mRNA polyadenylation [GO:1900364]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	meiotic cell cycle [GO:0051321]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; snRNA catabolic process [GO:0016076]	NELF complex [GO:0032021]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; RNA binding [GO:0003723]	14-3-3 protein binding [GO:0071889]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]
d2bz3d2_d2vbaa2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2bz4a2_d4jgaa1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d2bz4b2_d1m3zb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2bz5b__d2vwca___1	Metazoa	Fungi	Chordata	Ascomycota	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]
d2bzaa__d1hao.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d2bzca__d4yvna2__1	Viridiplantae		Streptophyta	Firmicutes	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]	chloroplast thylakoid membrane [GO:0009535]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2bzda1_d4gezg___1			Actinobacteria	Negarnaviricota	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2bzdb3_d1bgmm3__1			Actinobacteria		extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]		metabolic process [GO:0008152]		extracellular region [GO:0005576]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	
d2bzdb3_d3t08d1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	metabolic process [GO:0008152]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2bzdc1_d4cpmb___1			Actinobacteria	Negarnaviricota	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2bzdc1_d4hzwa1__1			Actinobacteria	Negarnaviricota	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	extracellular region [GO:0005576]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2bzrb1_d4i52i___1			Actinobacteria	Cyanobacteria	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; menaquinone biosynthetic process [GO:0009234]; phylloquinone biosynthetic process [GO:0042372]	carbon fixation [GO:0015977]	menaquinone biosynthetic process [GO:0009234]; phylloquinone biosynthetic process [GO:0042372]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]	1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]
d2bzrc1_d1yg8k___1			Actinobacteria	Proteobacteria	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	carbon fixation [GO:0015977]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2bzrd1_d3ib9b2__1			Actinobacteria	Actinobacteria	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	carbon fixation [GO:0015977]	fatty acid biosynthetic process [GO:0006633]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	acetyl-CoA carboxylase complex [GO:0009317]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]
d2bzrd1_d5ctcb1__1		Fungi	Actinobacteria	Ascomycota	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	carbon fixation [GO:0015977]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; propionyl-CoA carboxylase activity [GO:0004658]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d2bzsa__d3gfra___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d2bzua__d3qnda___1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	viral capsid [GO:0019028]		metal ion binding [GO:0046872]
d2bzza2_d3d6oa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; chemotaxis [GO:0006935]; defense response to virus [GO:0051607]; neutrophil degranulation [GO:0043312]; RNA catabolic process [GO:0006401]; RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	chemotaxis [GO:0006935]; defense response to virus [GO:0051607]; neutrophil degranulation [GO:0043312]; RNA catabolic process [GO:0006401]; RNA phosphodiester bond hydrolysis [GO:0090501]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d2c00a1_d3rv4a1__1			Proteobacteria	Proteobacteria	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2c04b2_d1okkd2__1			Deinococcus-Thermus	Deinococcus-Thermus	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]	signal recognition particle [GO:0048500]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d2c06a1_d4vuba___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; RNA binding [GO:0003723]	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity [GO:0008657]; plasmid maintenance [GO:0006276]		plasmid maintenance [GO:0006276]			DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; RNA binding [GO:0003723]	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity [GO:0008657]
d2c0aa__d4ur8b___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	5-dehydro-4-deoxyglucarate dehydratase activity [GO:0047448]; D-glucarate catabolic process [GO:0042838]	metabolic process [GO:0008152]	D-glucarate catabolic process [GO:0042838]	cytosol [GO:0005829]; membrane [GO:0016020]		(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]	5-dehydro-4-deoxyglucarate dehydratase activity [GO:0047448]
d2c0ac__d1hfbh___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	metabolic process [GO:0008152]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]
d2c0da__d1n8jk___1			Apicomplexa	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]	thioredoxin peroxidase activity [GO:0008379]	thioredoxin peroxidase activity [GO:0008379]
d2c0db__d1x9wb___1			Apicomplexa	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	thioredoxin peroxidase activity [GO:0008379]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2c0ea2_d2c0gb2__1	Metazoa	Metazoa	Arthropoda	Arthropoda	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; protein homodimerization activity [GO:0042803]; dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; protein homodimerization activity [GO:0042803]; dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	protein homodimerization activity [GO:0042803]	protein homodimerization activity [GO:0042803]
d2c0ga2_d1g7ea___1	Metazoa	Metazoa	Arthropoda	Chordata	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; protein homodimerization activity [GO:0042803]; dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; melanosome [GO:0042470]; smooth endoplasmic reticulum [GO:0005790]; transport vesicle [GO:0030133]; chaperone binding [GO:0051087]; protein homodimerization activity [GO:0042803]; activation of MAPK activity [GO:0000187]; intracellular protein transport [GO:0006886]; negative regulation of gene expression [GO:0010629]; negative regulation of protein secretion [GO:0050709]; positive regulation of gene expression [GO:0010628]; protein folding [GO:0006457]; protein secretion [GO:0009306]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; response to endoplasmic reticulum stress [GO:0034976]	dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	activation of MAPK activity [GO:0000187]; intracellular protein transport [GO:0006886]; negative regulation of gene expression [GO:0010629]; negative regulation of protein secretion [GO:0050709]; positive regulation of gene expression [GO:0010628]; protein folding [GO:0006457]; protein secretion [GO:0009306]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; response to endoplasmic reticulum stress [GO:0034976]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; melanosome [GO:0042470]; smooth endoplasmic reticulum [GO:0005790]; transport vesicle [GO:0030133]	protein homodimerization activity [GO:0042803]	chaperone binding [GO:0051087]; protein homodimerization activity [GO:0042803]
d2c0gb1_d2m66a___1	Metazoa	Metazoa	Arthropoda	Chordata	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; protein homodimerization activity [GO:0042803]; dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; melanosome [GO:0042470]; smooth endoplasmic reticulum [GO:0005790]; transport vesicle [GO:0030133]; chaperone binding [GO:0051087]; protein homodimerization activity [GO:0042803]; activation of MAPK activity [GO:0000187]; intracellular protein transport [GO:0006886]; negative regulation of gene expression [GO:0010629]; negative regulation of protein secretion [GO:0050709]; positive regulation of gene expression [GO:0010628]; protein folding [GO:0006457]; protein secretion [GO:0009306]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; response to endoplasmic reticulum stress [GO:0034976]	dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	activation of MAPK activity [GO:0000187]; intracellular protein transport [GO:0006886]; negative regulation of gene expression [GO:0010629]; negative regulation of protein secretion [GO:0050709]; positive regulation of gene expression [GO:0010628]; protein folding [GO:0006457]; protein secretion [GO:0009306]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; response to endoplasmic reticulum stress [GO:0034976]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; melanosome [GO:0042470]; smooth endoplasmic reticulum [GO:0005790]; transport vesicle [GO:0030133]	protein homodimerization activity [GO:0042803]	chaperone binding [GO:0051087]; protein homodimerization activity [GO:0042803]
d2c0ha1_d1e5ja___1	Metazoa		Mollusca	Firmicutes	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; mannan catabolic process [GO:0046355]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	mannan catabolic process [GO:0046355]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]
d2c0ka__d1clsd___1	Metazoa	Metazoa	Arthropoda	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2c0kb__d1yhun___1	Metazoa	Metazoa	Arthropoda	Annelida	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2c0ra__d1ohva___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	L-serine biosynthetic process [GO:0006564]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	cytoplasm [GO:0005737]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]	(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]
d2c12b1_d1t9gc1__1	Fungi	Metazoa	Ascomycota	Chordata	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	electron transfer activity [GO:0009055]
d2c12c1_d5jscc2__1	Fungi		Ascomycota	Proteobacteria	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]				FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d2c12f1_d1w07b2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; peroxisome [GO:0005777]; plasmodesma [GO:0009506]; acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; jasmonic acid biosynthetic process [GO:0009695]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676]; response to cadmium ion [GO:0046686]; response to fungus [GO:0009620]; response to wounding [GO:0009611]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; jasmonic acid biosynthetic process [GO:0009695]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676]; response to cadmium ion [GO:0046686]; response to fungus [GO:0009620]; response to wounding [GO:0009611]		cytosol [GO:0005829]; peroxisome [GO:0005777]; plasmodesma [GO:0009506]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]
d2c12f1_d2cx9d1__1	Fungi		Ascomycota	Deinococcus-Thermus	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]				FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d2c1fa1_d1w0oa1__1	Fungi		Chytridiomycota	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]; ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]	xylan catabolic process [GO:0045493]	ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]	endo-1,4-beta-xylanase activity [GO:0031176]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; sialic acid binding [GO:0033691]
d2c1ia1_d2f18a3__1		Metazoa	Firmicutes	Arthropoda	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; pathogenesis [GO:0009405]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]; pathogenesis [GO:0009405]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d2c1ja__d2c74a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercalated disc [GO:0014704]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; identical protein binding [GO:0042802]; insulin-like growth factor receptor binding [GO:0005159]; ion channel binding [GO:0044325]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; sodium channel regulator activity [GO:0017080]; glucocorticoid catabolic process [GO:0006713]; glucocorticoid receptor signaling pathway [GO:0042921]; intracellular protein transport [GO:0006886]; membrane depolarization during action potential [GO:0086010]; membrane organization [GO:0061024]; negative regulation of dendrite morphogenesis [GO:0050774]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of neuron differentiation [GO:0045664]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; regulation of sodium ion transport [GO:0002028]; regulation of synaptic plasticity [GO:0048167]; substantia nigra development [GO:0021762]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	glucocorticoid catabolic process [GO:0006713]; glucocorticoid receptor signaling pathway [GO:0042921]; intracellular protein transport [GO:0006886]; membrane depolarization during action potential [GO:0086010]; membrane organization [GO:0061024]; negative regulation of dendrite morphogenesis [GO:0050774]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of neuron differentiation [GO:0045664]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; regulation of sodium ion transport [GO:0002028]; regulation of synaptic plasticity [GO:0048167]; substantia nigra development [GO:0021762]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercalated disc [GO:0014704]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	actin binding [GO:0003779]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; identical protein binding [GO:0042802]; insulin-like growth factor receptor binding [GO:0005159]; ion channel binding [GO:0044325]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; sodium channel regulator activity [GO:0017080]
d2c1ma__d3btrc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; androgen binding [GO:0005497]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; nuclear receptor activity [GO:0004879]; POU domain binding [GO:0070974]; protein dimerization activity [GO:0046983]; RNA polymerase II general transcription initiation factor binding [GO:0001091]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]; activation of prostate induction by androgen receptor signaling pathway [GO:0060520]; androgen receptor signaling pathway [GO:0030521]; animal organ formation [GO:0048645]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to steroid hormone stimulus [GO:0071383]; cellular response to testosterone stimulus [GO:0071394]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; epithelial cell morphogenesis [GO:0003382]; in utero embryonic development [GO:0001701]; intracellular receptor signaling pathway [GO:0030522]; lateral sprouting involved in mammary gland duct morphogenesis [GO:0060599]; Leydig cell differentiation [GO:0033327]; male genitalia morphogenesis [GO:0048808]; male somatic sex determination [GO:0019102]; mammary gland alveolus development [GO:0060749]; morphogenesis of an epithelial fold [GO:0060571]; multicellular organism growth [GO:0035264]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of integrin biosynthetic process [GO:0045720]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of integrin biosynthetic process [GO:0045726]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription, DNA-templated [GO:0045893]; prostate gland development [GO:0030850]; prostate gland epithelium morphogenesis [GO:0060740]; prostate gland growth [GO:0060736]; protein deubiquitination [GO:0016579]; regulation of developmental growth [GO:0048638]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of systemic arterial blood pressure [GO:0003073]; seminiferous tubule development [GO:0072520]; sex differentiation [GO:0007548]; signal transduction [GO:0007165]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]	entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	activation of prostate induction by androgen receptor signaling pathway [GO:0060520]; androgen receptor signaling pathway [GO:0030521]; animal organ formation [GO:0048645]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to steroid hormone stimulus [GO:0071383]; cellular response to testosterone stimulus [GO:0071394]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; epithelial cell morphogenesis [GO:0003382]; intracellular receptor signaling pathway [GO:0030522]; in utero embryonic development [GO:0001701]; lateral sprouting involved in mammary gland duct morphogenesis [GO:0060599]; Leydig cell differentiation [GO:0033327]; male genitalia morphogenesis [GO:0048808]; male somatic sex determination [GO:0019102]; mammary gland alveolus development [GO:0060749]; morphogenesis of an epithelial fold [GO:0060571]; multicellular organism growth [GO:0035264]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of integrin biosynthetic process [GO:0045720]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of integrin biosynthetic process [GO:0045726]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; prostate gland development [GO:0030850]; prostate gland epithelium morphogenesis [GO:0060740]; prostate gland growth [GO:0060736]; protein deubiquitination [GO:0016579]; regulation of developmental growth [GO:0048638]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of systemic arterial blood pressure [GO:0003073]; seminiferous tubule development [GO:0072520]; sex differentiation [GO:0007548]; signal transduction [GO:0007165]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription, DNA-templated [GO:0006351]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]	androgen binding [GO:0005497]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; nuclear receptor activity [GO:0004879]; POU domain binding [GO:0070974]; protein dimerization activity [GO:0046983]; RNA polymerase II general transcription initiation factor binding [GO:0001091]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]
d2c1oa2_d2iepa1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	cell junction [GO:0030054]; cell projection [GO:0042995]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; cochlea development [GO:0090102]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to muscle activity [GO:0014850]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cochlea development [GO:0090102]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to muscle activity [GO:0014850]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell junction [GO:0030054]; cell projection [GO:0042995]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]	metal ion binding [GO:0046872]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2c1ol1_d1u95a2__1	Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d2c1ol2_d6bith___1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]		cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	metal ion binding [GO:0046872]	cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]
d2c1pa1_d2h32a___1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; membrane [GO:0016020]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; membrane [GO:0016020]	metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2c1pa1_d2i5yl2__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2c1pa2_d3puca1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	metal ion binding [GO:0046872]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d2c1uc2_d1umma___1												
d2c1uc2_d2n9ia___1		Metazoa		Chordata		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]		activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]		electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2c20a__d1g6ke___1			Firmicutes	Firmicutes	coenzyme binding [GO:0050662]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-glucose 4-epimerase activity [GO:0003978]; galactose metabolic process [GO:0006012]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; sporulation resulting in formation of a cellular spore [GO:0030435]	galactose metabolic process [GO:0006012]	sporulation resulting in formation of a cellular spore [GO:0030435]			coenzyme binding [GO:0050662]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-glucose 4-epimerase activity [GO:0003978]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]
d2c20a__d4gvxc___1			Firmicutes	Proteobacteria	coenzyme binding [GO:0050662]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-glucose 4-epimerase activity [GO:0003978]; galactose metabolic process [GO:0006012]	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	galactose metabolic process [GO:0006012]				coenzyme binding [GO:0050662]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-glucose 4-epimerase activity [GO:0003978]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2c20d__d1p45a___1			Firmicutes	Actinobacteria	coenzyme binding [GO:0050662]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-glucose 4-epimerase activity [GO:0003978]; galactose metabolic process [GO:0006012]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	galactose metabolic process [GO:0006012]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]	coenzyme binding [GO:0050662]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-glucose 4-epimerase activity [GO:0003978]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d2c2bc__d1k3ub___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]; threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	threonine biosynthetic process [GO:0009088]	tryptophan biosynthetic process [GO:0000162]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]
d2c2bf__d3dwga1__1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]; threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; O-phosphoserine sulfhydrylase activity [GO:0033847]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	threonine biosynthetic process [GO:0009088]	cysteine biosynthetic process from serine [GO:0006535]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; O-phosphoserine sulfhydrylase activity [GO:0033847]; pyridoxal phosphate binding [GO:0030170]
d2c2fa__d4p18d___1		Metazoa	Deinococcus-Thermus	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2c2vi__d2daxa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; UBC13-MMS2 complex [GO:0031372]; UBC13-UEV1A complex [GO:0035370]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; activation of MAPK activity [GO:0000187]; cellular protein modification process [GO:0006464]; DNA double-strand break processing [GO:0000729]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone ubiquitination [GO:0016574]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of DNA repair [GO:0045739]; positive regulation of histone modification [GO:0031058]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of DNA repair [GO:0006282]; regulation of histone ubiquitination [GO:0033182]; T cell receptor signaling pathway [GO:0050852]		activation of MAPK activity [GO:0000187]; cellular protein modification process [GO:0006464]; DNA double-strand break processing [GO:0000729]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone ubiquitination [GO:0016574]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of DNA repair [GO:0045739]; positive regulation of histone modification [GO:0031058]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of DNA repair [GO:0006282]; regulation of histone ubiquitination [GO:0033182]; T cell receptor signaling pathway [GO:0050852]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; UBC13-MMS2 complex [GO:0031372]; UBC13-UEV1A complex [GO:0035370]; ubiquitin ligase complex [GO:0000151]		ATP binding [GO:0005524]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	
d2c2vl__d1wzwa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; UBC13-MMS2 complex [GO:0031372]; UBC13-UEV1A complex [GO:0035370]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; activation of MAPK activity [GO:0000187]; cellular protein modification process [GO:0006464]; DNA double-strand break processing [GO:0000729]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone ubiquitination [GO:0016574]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of DNA repair [GO:0045739]; positive regulation of histone modification [GO:0031058]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of DNA repair [GO:0006282]; regulation of histone ubiquitination [GO:0033182]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; ubiquitin ligase complex [GO:0000151]; ISG15 transferase activity [GO:0042296]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; ISG15-protein conjugation [GO:0032020]; negative regulation of type I interferon production [GO:0032480]; translesion synthesis [GO:0019985]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; cellular protein modification process [GO:0006464]; DNA double-strand break processing [GO:0000729]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone ubiquitination [GO:0016574]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of DNA repair [GO:0045739]; positive regulation of histone modification [GO:0031058]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of DNA repair [GO:0006282]; regulation of histone ubiquitination [GO:0033182]; T cell receptor signaling pathway [GO:0050852]	cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; ISG15-protein conjugation [GO:0032020]; negative regulation of type I interferon production [GO:0032480]; translesion synthesis [GO:0019985]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; UBC13-MMS2 complex [GO:0031372]; UBC13-UEV1A complex [GO:0035370]; ubiquitin ligase complex [GO:0000151]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; ubiquitin ligase complex [GO:0000151]	ATP binding [GO:0005524]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	ISG15 transferase activity [GO:0042296]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]
d2c2ya1_d1diga2__1		Metazoa	Actinobacteria	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity [GO:0004486]; 10-formyltetrahydrofolate biosynthetic process [GO:0009257]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; folic acid metabolic process [GO:0046655]; heart development [GO:0007507]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; one-carbon metabolic process [GO:0006730]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; serine family amino acid biosynthetic process [GO:0009070]; serine family amino acid metabolic process [GO:0009069]; somite development [GO:0061053]; tetrahydrofolate interconversion [GO:0035999]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	10-formyltetrahydrofolate biosynthetic process [GO:0009257]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; folic acid metabolic process [GO:0046655]; heart development [GO:0007507]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; one-carbon metabolic process [GO:0006730]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; serine family amino acid biosynthetic process [GO:0009070]; serine family amino acid metabolic process [GO:0009069]; somite development [GO:0061053]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity [GO:0004486]
d2c31b1_d1icia1__1			Proteobacteria	Euryarchaeota	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	oxalate catabolic process [GO:0033611]			cytoplasm [GO:0005737]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d2c31b2_d2bp7a___1			Proteobacteria	Proteobacteria	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]	oxalate catabolic process [GO:0033611]				ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]
d2c31b3_d1kekb2__1			Proteobacteria	Proteobacteria	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	oxalate catabolic process [GO:0033611]	electron transport chain [GO:0022900]		cytoplasm [GO:0005737]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d2c35b2_d2ja7s2__1	Metazoa	Fungi	Chordata	Ascomycota	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; RNA polymerase II, core complex [GO:0005665]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; translation initiation factor binding [GO:0031369]; 7-methylguanosine mRNA capping [GO:0006370]; apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral transcription [GO:0050434]; regulation of gene silencing by miRNA [GO:0060964]; RNA metabolic process [GO:0016070]; snRNA transcription by RNA polymerase II [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]; transcription-coupled nucleotide-excision repair [GO:0006283]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	7-methylguanosine mRNA capping [GO:0006370]; apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral transcription [GO:0050434]; regulation of gene silencing by miRNA [GO:0060964]; RNA metabolic process [GO:0016070]; snRNA transcription by RNA polymerase II [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; transcription by RNA polymerase II [GO:0006366]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; RNA polymerase II, core complex [GO:0005665]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; translation initiation factor binding [GO:0031369]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]
d2c35c__d1yt3a1__1	Metazoa		Chordata	Proteobacteria	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; RNA polymerase II, core complex [GO:0005665]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; translation initiation factor binding [GO:0031369]; 7-methylguanosine mRNA capping [GO:0006370]; apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral transcription [GO:0050434]; regulation of gene silencing by miRNA [GO:0060964]; RNA metabolic process [GO:0016070]; snRNA transcription by RNA polymerase II [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]; transcription-coupled nucleotide-excision repair [GO:0006283]	cytoplasm [GO:0005737]; 3'-5'-exoribonuclease activity [GO:0000175]; nucleic acid binding [GO:0003676]; nucleotide binding [GO:0000166]; ribonuclease D activity [GO:0033890]; tRNA 3'-end processing [GO:0042780]	7-methylguanosine mRNA capping [GO:0006370]; apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral transcription [GO:0050434]; regulation of gene silencing by miRNA [GO:0060964]; RNA metabolic process [GO:0016070]; snRNA transcription by RNA polymerase II [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; transcription by RNA polymerase II [GO:0006366]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	tRNA 3'-end processing [GO:0042780]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; RNA polymerase II, core complex [GO:0005665]	cytoplasm [GO:0005737]	DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; translation initiation factor binding [GO:0031369]	3'-5'-exoribonuclease activity [GO:0000175]; nucleic acid binding [GO:0003676]; nucleotide binding [GO:0000166]; ribonuclease D activity [GO:0033890]
d2c35h1_d3e9ic1__1	Metazoa		Chordata	Firmicutes	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; RNA polymerase II, core complex [GO:0005665]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; translation initiation factor binding [GO:0031369]; 7-methylguanosine mRNA capping [GO:0006370]; apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral transcription [GO:0050434]; regulation of gene silencing by miRNA [GO:0060964]; RNA metabolic process [GO:0016070]; snRNA transcription by RNA polymerase II [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]; transcription-coupled nucleotide-excision repair [GO:0006283]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	7-methylguanosine mRNA capping [GO:0006370]; apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral transcription [GO:0050434]; regulation of gene silencing by miRNA [GO:0060964]; RNA metabolic process [GO:0016070]; snRNA transcription by RNA polymerase II [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; transcription by RNA polymerase II [GO:0006366]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	lysyl-tRNA aminoacylation [GO:0006430]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; RNA polymerase II, core complex [GO:0005665]	cytoplasm [GO:0005737]	DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; translation initiation factor binding [GO:0031369]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d2c37b2_d1oyrf2__1			Crenarchaeota	Firmicutes	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d2c37c2_d2c38x2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c37c2_d2wnra2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c37d1_d4qnkg2__1		Viridiplantae	Crenarchaeota	Streptophyta	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	rRNA catabolic process [GO:0016075]	histidine biosynthetic process [GO:0000105]	cytoplasmic exosome (RNase complex) [GO:0000177]	chloroplast [GO:0009507]	3'-5'-exoribonuclease activity [GO:0000175]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2c37d2_d2br2c2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c37h1_d1udoa1__1			Crenarchaeota	Aquificae	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d2c37i2_d2nn6a2__1		Metazoa	Crenarchaeota	Chordata	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; RNA binding [GO:0003723]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; regulation of mRNA stability [GO:0043488]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA processing [GO:0006364]	rRNA catabolic process [GO:0016075]	exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; regulation of mRNA stability [GO:0043488]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA processing [GO:0006364]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	3'-5'-exoribonuclease activity [GO:0000175]	RNA binding [GO:0003723]
d2c37l1_d2po2b1__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c37l2_d2ba1d2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2c37n2_d2c39s2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c37n2_d2wnrd2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c37o2_d2ba0d2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c37p1_d2f1di1__1		Viridiplantae	Crenarchaeota	Streptophyta	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	rRNA catabolic process [GO:0016075]	histidine biosynthetic process [GO:0000105]	cytoplasmic exosome (RNase complex) [GO:0000177]	chloroplast [GO:0009507]	3'-5'-exoribonuclease activity [GO:0000175]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2c37p2_d2jebb2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	rRNA catabolic process [GO:0016075]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d2c37r2_d2c38u2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c37s2_d2ba0g2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c37t2_d2po1b2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c37x1_d1y5yb___1			Crenarchaeota	Proteobacteria	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; carbon-nitrogen lyase activity [GO:0016840]; carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	rRNA catabolic process [GO:0016075]	carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]	3'-5'-exoribonuclease activity [GO:0000175]	carbon-nitrogen lyase activity [GO:0016840]
d2c38a2_d3m85i2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2c38b1_d2f1do2__1		Viridiplantae	Crenarchaeota	Streptophyta	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	rRNA catabolic process [GO:0016075]	histidine biosynthetic process [GO:0000105]	cytoplasmic exosome (RNase complex) [GO:0000177]	chloroplast [GO:0009507]	3'-5'-exoribonuclease activity [GO:0000175]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2c38b2_d3b4ta2__1			Crenarchaeota	Actinobacteria	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	plasma membrane [GO:0005886]; 3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasmic exosome (RNase complex) [GO:0000177]	plasma membrane [GO:0005886]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d2c38g2_d2nn6e2__1		Metazoa	Crenarchaeota	Chordata	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; RNA binding [GO:0003723]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; regulation of mRNA stability [GO:0043488]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA processing [GO:0006364]	rRNA catabolic process [GO:0016075]	exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; regulation of mRNA stability [GO:0043488]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA processing [GO:0006364]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	3'-5'-exoribonuclease activity [GO:0000175]	RNA binding [GO:0003723]
d2c38h2_d2br2o2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c38l1_d1z5bb2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	rRNA catabolic process [GO:0016075]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]
d2c38p2_d1oyrd2__1			Crenarchaeota	Firmicutes	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d2c38q2_d2ba1e2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2c38r2_d2br2a2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c38s2_d2c37h2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c38s2_d2wp8b2__1		Fungi	Crenarchaeota	Ascomycota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; exosome (RNase complex) [GO:0000178]; mitochondrion [GO:0005739]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleus [GO:0005634]; 3'-5'-exoribonuclease activity [GO:0000175]; endonuclease activity [GO:0004519]; endoribonuclease activity [GO:0004521]; tRNA binding [GO:0000049]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; mRNA processing [GO:0006397]; ncRNA 3'-end processing [GO:0043628]; nonfunctional rRNA decay [GO:0070651]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; mRNA processing [GO:0006397]; ncRNA 3'-end processing [GO:0043628]; nonfunctional rRNA decay [GO:0070651]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]; exosome (RNase complex) [GO:0000178]; mitochondrion [GO:0005739]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleus [GO:0005634]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]; endonuclease activity [GO:0004519]; endoribonuclease activity [GO:0004521]; tRNA binding [GO:0000049]
d2c38x1_d1udqa1__1			Crenarchaeota	Aquificae	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d2c39d1_d2qoue1__1			Crenarchaeota		cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]		rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]	
d2c39f1_d3m7ng1__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2c39f2_d2c38c2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c39j2_d2pnzb2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c39j2_d3m7nf2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2c39l2_d2po0b2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c39p1_d3l7zg1__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	rRNA catabolic process [GO:0016075]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d2c39p2_d2c37w2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c39q2_d2jeab2__1			Crenarchaeota	Crenarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	rRNA catabolic process [GO:0016075]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d2c39r1_d1hnwi___1			Crenarchaeota	Deinococcus-Thermus	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	rRNA catabolic process [GO:0016075]	translation [GO:0006412]	cytoplasmic exosome (RNase complex) [GO:0000177]	ribosome [GO:0005840]	3'-5'-exoribonuclease activity [GO:0000175]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2c39s2_d2po2a2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c39v2_d2wnrb2__1			Crenarchaeota	Euryarchaeota	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2c3da2_d1h7wb3__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; 2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d2c3mb1_d2r5nb2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	electron transport chain [GO:0022900]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d2c3mb3_d2bffb2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	electron transport chain [GO:0022900]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]
d2c3na2_d1bayb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]
d2c3nb1_d1gume2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2c3nc1_d2fd3b___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2c3nc2_d1tu7a1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	glutathione transferase activity [GO:0004364]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2c3oa1_d4fegb3__1			Proteobacteria		cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]		electron transport chain [GO:0022900]		cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	
d2c3oa3_d3exgr2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2c3ob2_d4judx1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	electron transport chain [GO:0022900]	mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2c3pa1_d1mczm2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	electron transport chain [GO:0022900]	mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2c3pa3_d3exg62__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2c3pb1_d1yi0a3__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	electron transport chain [GO:0022900]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2c3pb2_d2pdab1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	electron transport chain [GO:0022900]	electron transport chain [GO:0022900]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d2c3qa1_d1t1vb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d2c3qb1_d4aj6b___1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]	protein disulfide oxidoreductase activity [GO:0015035]
d2c3qd1_d1ml6b2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	glutathione metabolic process [GO:0006749]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2c3tc2_d3csja1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2c3td2_d1z9hb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]	electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]
d2c3ua2_d2ji8a3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	electron transport chain [GO:0022900]	oxalate catabolic process [GO:0033611]	cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d2c3ub1_d5dgda3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	electron transport chain [GO:0022900]	mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2c3ub2_d2wvha3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	electron transport chain [GO:0022900]		cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2c3ya1_d2ji8a2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	electron transport chain [GO:0022900]	oxalate catabolic process [GO:0033611]	cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d2c3ya2_d5hjea1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	electron transport chain [GO:0022900]		cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d2c41a__d4m35d___1			Cyanobacteria	Actinobacteria	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2c41d__d3uoib___1			Cyanobacteria	Actinobacteria	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2c41e__d1zs3c___1			Cyanobacteria		cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	
d2c41e__d4dr0a___1			Cyanobacteria	Firmicutes	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2c41h__d4pg0a___1			Cyanobacteria	Cyanobacteria	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]
d2c41i__d1riba___1			Cyanobacteria	Proteobacteria	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2c41i__d5u1ba___1			Cyanobacteria	Proteobacteria	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; efflux transmembrane transporter activity [GO:0015562]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	efflux transmembrane transporter activity [GO:0015562]
d2c41k__d3gvyc___1			Cyanobacteria	Proteobacteria	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2c41k__d5ww5d___1			Cyanobacteria	Actinobacteria	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2c42a2_d2ezta2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	electron transport chain [GO:0022900]		cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d2c42a3_d3dufd2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	electron transport chain [GO:0022900]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2c42b2_d1t9dd3__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	electron transport chain [GO:0022900]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytoplasm [GO:0005737]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2c44b__d1zc9a___1			Proteobacteria	Proteobacteria	cell pole [GO:0060187]; cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; L-cysteine desulfhydrase activity [GO:0080146]; potassium ion binding [GO:0030955]; pyridoxal phosphate binding [GO:0030170]; tryptophanase activity [GO:0009034]; protein homotetramerization [GO:0051289]; tryptophan catabolic process [GO:0006569]	2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	protein homotetramerization [GO:0051289]; tryptophan catabolic process [GO:0006569]		cell pole [GO:0060187]; cytosol [GO:0005829]; membrane [GO:0016020]		identical protein binding [GO:0042802]; L-cysteine desulfhydrase activity [GO:0080146]; potassium ion binding [GO:0030955]; pyridoxal phosphate binding [GO:0030170]; tryptophanase activity [GO:0009034]	2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d2c4fh1_d1a0la___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2c4ga2_d2e9na___1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; histone kinase activity (H3-T11 specific) [GO:0035402]; kinase activity [GO:0016301]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to mechanical stimulus [GO:0071260]; chromatin-mediated maintenance of transcription [GO:0048096]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intracellular signal transduction [GO:0035556]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of mitotic nuclear division [GO:0045839]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell cycle [GO:0045787]; protein phosphorylation [GO:0006468]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of mitotic centrosome separation [GO:0046602]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010767]; replicative senescence [GO:0090399]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to mechanical stimulus [GO:0071260]; chromatin-mediated maintenance of transcription [GO:0048096]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intracellular signal transduction [GO:0035556]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of mitotic nuclear division [GO:0045839]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell cycle [GO:0045787]; protein phosphorylation [GO:0006468]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of mitotic centrosome separation [GO:0046602]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010767]; replicative senescence [GO:0090399]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; histone kinase activity (H3-T11 specific) [GO:0035402]; kinase activity [GO:0016301]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d2c4ja1_d4naxb2__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	transferase activity [GO:0016740]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	transferase activity [GO:0016740]
d2c4ja2_d5b8bc___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]; activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]
d2c4jb1_d6gswa1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d2c4jb2_d3uvha1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]
d2c4jc1_d4nhzb2__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	transferase activity [GO:0016740]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	transferase activity [GO:0016740]
d2c4jc2_d2h66d___1	Metazoa		Chordata	Apicomplexa	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cell [GO:0005623]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	peroxiredoxin activity [GO:0051920]
d2c4jd1_d2vctf2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione transferase activity [GO:0004364]
d2c4jd1_d4chsa2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytoplasm [GO:0005737]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione transferase activity [GO:0004364]
d2c4la__d2htqa___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2c4na1_d1yv9a1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; carbohydrate metabolic process [GO:0005975]; UMP catabolic process [GO:0046050]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]; UMP catabolic process [GO:0046050]		cytosol [GO:0005829]		5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2c4yb__d1gav3___1					T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2c4za__d1gavm___1					T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2c4zc__d1gavw___1					T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2c59a1_d4z3dc___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]; plastid [GO:0009536]; GDP-mannose 3,5-epimerase activity [GO:0047918]; NAD binding [GO:0051287]; L-ascorbic acid biosynthetic process [GO:0019853]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; 15-hydroxyprostaglandin dehydrogenase (NADP+) activity [GO:0047021]; carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; prostaglandin-E2 9-reductase activity [GO:0050221]; cyclooxygenase pathway [GO:0019371]; drug metabolic process [GO:0017144]; epithelial cell differentiation [GO:0030855]; oxidation-reduction process [GO:0055114]; vitamin K metabolic process [GO:0042373]	L-ascorbic acid biosynthetic process [GO:0019853]	cyclooxygenase pathway [GO:0019371]; drug metabolic process [GO:0017144]; epithelial cell differentiation [GO:0030855]; oxidation-reduction process [GO:0055114]; vitamin K metabolic process [GO:0042373]	cytosol [GO:0005829]; plastid [GO:0009536]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]	GDP-mannose 3,5-epimerase activity [GO:0047918]; NAD binding [GO:0051287]	15-hydroxyprostaglandin dehydrogenase (NADP+) activity [GO:0047021]; carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; prostaglandin-E2 9-reductase activity [GO:0050221]
d2c5aa1_d1hdcd___1	Viridiplantae		Streptophyta	Actinobacteria	cytosol [GO:0005829]; plastid [GO:0009536]; GDP-mannose 3,5-epimerase activity [GO:0047918]; NAD binding [GO:0051287]; L-ascorbic acid biosynthetic process [GO:0019853]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; C21-steroid hormone metabolic process [GO:0008207]	L-ascorbic acid biosynthetic process [GO:0019853]	C21-steroid hormone metabolic process [GO:0008207]	cytosol [GO:0005829]; plastid [GO:0009536]		GDP-mannose 3,5-epimerase activity [GO:0047918]; NAD binding [GO:0051287]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]
d2c5aa1_d1hetb2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]; plastid [GO:0009536]; GDP-mannose 3,5-epimerase activity [GO:0047918]; NAD binding [GO:0051287]; L-ascorbic acid biosynthetic process [GO:0019853]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	L-ascorbic acid biosynthetic process [GO:0019853]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; plastid [GO:0009536]	cytosol [GO:0005829]	GDP-mannose 3,5-epimerase activity [GO:0047918]; NAD binding [GO:0051287]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d2c5cd__d5d3db1__1				Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d2c5ce__d1c48a___1					extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d2c5ci__d1chqe___1				Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	toxin activity [GO:0090729]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d2c5ga__d4oyyh___1	Metazoa	Fungi	Chordata	Ascomycota	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	extracellular region [GO:0005576]	acetylcholinesterase activity [GO:0003990]	cutinase activity [GO:0050525]
d2c5lb__d1yrba2__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]		GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]
d2c5nd1_d2g9xd2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2c5ob1_d5lmkd2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2c5pd3_d2c5pb4__1												
d2c5pd4_d1f5qb1__1		Metazoa		Chordata		Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]		anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]		Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]		ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2c5tb1_d4nstd2__1		Metazoa		Chordata		cyclin K-CDK12 complex [GO:0002944]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]		mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]		cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin K-CDK12 complex [GO:0002944]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]
d2c5tb2_d3bhvd1__1		Metazoa		Chordata		Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]		anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]		Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]		ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2c5td1_d4bchb2__1		Metazoa		Chordata		chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]		cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]		chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]		7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2c5td2_d4eosb1__1		Metazoa		Chordata		Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]		anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]		Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]		ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2c5vb2_d1c9ba1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2c5xc__d2j2ib___1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; manganese ion binding [GO:0030145]; protein serine/threonine kinase activity [GO:0004674]; ribosomal small subunit binding [GO:0043024]; transcription factor binding [GO:0008134]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular detoxification [GO:1990748]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan metabolic process [GO:0030212]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular detoxification [GO:1990748]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan metabolic process [GO:0030212]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; manganese ion binding [GO:0030145]; protein serine/threonine kinase activity [GO:0004674]; ribosomal small subunit binding [GO:0043024]; transcription factor binding [GO:0008134]
d2c5xd2_d1okvb1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2c61a2_d2hldw3__1		Fungi	Euryarchaeota	Ascomycota	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2c61a2_d3b2qa3__1			Euryarchaeota	Euryarchaeota	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2c64a2_d1b37b2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]
d2c64a2_d3cnja2__1	Metazoa		Chordata	Actinobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cholesterol metabolic process [GO:0008203]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]
d2c66a2_d1bkwa2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d2c66b2_d1ng3b2__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]; cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]
d2c66b2_d1tdoa2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]
d2c67b2_d1d7la2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d2c6ha__d8cppa___1			Actinobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2c6td2_d1pkdb1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2c6ua__d4n36c___1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; defense response [GO:0006952]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; signal transduction by protein phosphorylation [GO:0023014]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cell surface receptor signaling pathway [GO:0007166]; defense response [GO:0006952]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; signal transduction by protein phosphorylation [GO:0023014]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d2c70a2_d2igng2__1	Metazoa	Fungi	Chordata	Basidiomycota	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]
d2c71a1_d2iw0a1__1		Fungi	Firmicutes	Ascomycota	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; xylan catabolic process [GO:0045493]	chitin deacetylase activity [GO:0004099]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]	chitin deacetylase activity [GO:0004099]; metal ion binding [GO:0046872]
d2c72a2_d3qvpa2__1	Metazoa	Fungi	Chordata	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	extracellular region [GO:0005576]; flavin adenine dinucleotide binding [GO:0050660]; glucose oxidase activity [GO:0046562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	flavin adenine dinucleotide binding [GO:0050660]; glucose oxidase activity [GO:0046562]
d2c73a2_d3bhfa2__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	tetrahydrofolate metabolic process [GO:0046653]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	sarcosine oxidase activity [GO:0008115]
d2c73b2_d1f8ra2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]
d2c75b2_d1d5ta2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; midbody [GO:0030496]; GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]; negative regulation of axonogenesis [GO:0050771]; negative regulation of protein targeting to membrane [GO:0090315]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	negative regulation of axonogenesis [GO:0050771]; negative regulation of protein targeting to membrane [GO:0090315]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; midbody [GO:0030496]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]
d2c76a2_d1daoh2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d2c76a2_d1reoa2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]
d2c76b2_d1pbea2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d2c77a1_d3j3az2__1			Actinobacteria		extracellular region [GO:0005576]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]		cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]		extracellular region [GO:0005576]			
d2c77a3_d1crqa___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]		GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d2c78a1_d3ccrb1__1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]	cytoplasm [GO:0005737]	ribosome [GO:0005840]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2c78a3_d1o3yb1__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cell [GO:0005623]; cell junction [GO:0030054]; cell leading edge [GO:0031252]; COPI-coated vesicle [GO:0030137]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; late endosome [GO:0005770]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal membrane [GO:0005778]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; trans-Golgi network [GO:0005802]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; phospholipase D activator activity [GO:1990583]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; actin filament organization [GO:0007015]; cellular copper ion homeostasis [GO:0006878]; cellular response to virus [GO:0098586]; dendritic spine organization [GO:0097061]; Golgi to transport vesicle transport [GO:0055108]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; lysosomal membrane organization [GO:0097212]; mitotic cleavage furrow ingression [GO:1990386]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of endocytosis [GO:0045807]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of late endosome to lysosome transport [GO:1902824]; positive regulation of protein secretion [GO:0050714]; positive regulation of sodium ion transmembrane transport [GO:1902307]; postsynaptic actin cytoskeleton organization [GO:0098974]; protein transport [GO:0015031]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of phospholipid metabolic process [GO:1903725]; regulation of receptor internalization [GO:0002090]; synaptic vesicle budding [GO:0070142]; very-low-density lipoprotein particle assembly [GO:0034379]; vesicle-mediated transport [GO:0016192]		actin filament organization [GO:0007015]; cellular copper ion homeostasis [GO:0006878]; cellular response to virus [GO:0098586]; dendritic spine organization [GO:0097061]; Golgi to transport vesicle transport [GO:0055108]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; lysosomal membrane organization [GO:0097212]; mitotic cleavage furrow ingression [GO:1990386]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of endocytosis [GO:0045807]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of late endosome to lysosome transport [GO:1902824]; positive regulation of protein secretion [GO:0050714]; positive regulation of sodium ion transmembrane transport [GO:1902307]; postsynaptic actin cytoskeleton organization [GO:0098974]; protein transport [GO:0015031]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of phospholipid metabolic process [GO:1903725]; regulation of receptor internalization [GO:0002090]; synaptic vesicle budding [GO:0070142]; very-low-density lipoprotein particle assembly [GO:0034379]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]	cell [GO:0005623]; cell junction [GO:0030054]; cell leading edge [GO:0031252]; COPI-coated vesicle [GO:0030137]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; late endosome [GO:0005770]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal membrane [GO:0005778]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; trans-Golgi network [GO:0005802]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; phospholipase D activator activity [GO:1990583]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d2c79a2_d2f7pa3__1		Metazoa	Firmicutes	Arthropoda	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; xylan catabolic process [GO:0045493]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	xylan catabolic process [GO:0045493]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d2c7fa2_d1w91a2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]		alpha-L-arabinofuranosidase activity [GO:0046556]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d2c7fb2_d1bg9a2__1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		alpha-L-arabinofuranosidase activity [GO:0046556]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d2c7fc2_d3dypd3__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]	beta-galactosidase complex [GO:0009341]	alpha-L-arabinofuranosidase activity [GO:0046556]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2c7fc2_d3o6aa___1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]; cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	cytoplasm [GO:0005737]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]	alpha-L-arabinofuranosidase activity [GO:0046556]	cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]
d2c7fd2_d1jyvc5__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]	beta-galactosidase complex [GO:0009341]	alpha-L-arabinofuranosidase activity [GO:0046556]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2c7fd2_d3f4vb___1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	alpha-L-arabinofuranosidase activity [GO:0046556]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d2c7ff2_d1w2pa___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]		alpha-L-arabinofuranosidase activity [GO:0046556]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]
d2c7la__d1a01a___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2c7oa__d4mika___1		Metazoa	Proteobacteria	Chordata	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	DNA restriction-modification system [GO:0009307]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d2c7pa__d2uyca___1			Proteobacteria	Proteobacteria	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d2c7ra__d2fcab___1			Proteobacteria	Firmicutes	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	tRNA (guanine-N7-)-methyltransferase activity [GO:0008176]; RNA (guanine-N7)-methylation [GO:0036265]; tRNA methylation [GO:0030488]	DNA restriction-modification system [GO:0009307]	RNA (guanine-N7)-methylation [GO:0036265]; tRNA methylation [GO:0030488]			DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	tRNA (guanine-N7-)-methyltransferase activity [GO:0008176]
d2c7ra__d2i9ka___1			Proteobacteria	Proteobacteria	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d2c7ub2_d1bvlb___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2c7ue2_d3gmlb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2c7ya2_d1fj4c2__1	Viridiplantae		Streptophyta	Proteobacteria	endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]; acetyl-CoA C-acyltransferase activity [GO:0003988]; fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]	cytosol [GO:0005829]	acetyl-CoA C-acyltransferase activity [GO:0003988]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2c7yb2_d2vb7b1__1	Viridiplantae		Streptophyta	Proteobacteria	endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]; acetyl-CoA C-acyltransferase activity [GO:0003988]; fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]	cytosol [GO:0005829]	acetyl-CoA C-acyltransferase activity [GO:0003988]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2c7za2_d2vb9c1__1	Viridiplantae		Streptophyta	Proteobacteria	endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]; acetyl-CoA C-acyltransferase activity [GO:0003988]; fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]	cytosol [GO:0005829]	acetyl-CoA C-acyltransferase activity [GO:0003988]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2c80a1_d2imia2__1	Metazoa	Metazoa	Platyhelminthes	Arthropoda	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]		glutathione metabolic process [GO:0006749]		cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2c80a1_d3ljrb1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]		glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2c80b1_d4hz2b2__1	Metazoa		Platyhelminthes	Proteobacteria	glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]					glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d2c80b2_d1g6wa2__1	Metazoa	Fungi	Platyhelminthes	Ascomycota	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]
d2c80b2_d2o8vb___1	Metazoa		Platyhelminthes	Proteobacteria	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutathione transferase activity [GO:0004364]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2c8ad__d4h0xa1__1		Metazoa	Firmicutes	Chordata		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]		actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2c8ca__d1og4a___1		Metazoa	Firmicutes	Chordata		anchored component of plasma membrane [GO:0046658]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; NAD glycohydrolase activity [GO:0061810]; NAD(P)+-protein-arginine ADP-ribosyltransferase activity [GO:0003956]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD catabolic process [GO:0019677]; peptidyl-arginine ADP-ribosylation [GO:0018120]; protein ADP-ribosylation [GO:0006471]		NAD catabolic process [GO:0019677]; peptidyl-arginine ADP-ribosylation [GO:0018120]; protein ADP-ribosylation [GO:0006471]		anchored component of plasma membrane [GO:0046658]		hydrolase activity, acting on glycosyl bonds [GO:0016798]; NAD(P)+-protein-arginine ADP-ribosyltransferase activity [GO:0003956]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD glycohydrolase activity [GO:0061810]
d2c8cb__d4l70a2__1		Metazoa	Firmicutes	Chordata		centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; catalytic activity [GO:0003824]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]		DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]		centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]		catalytic activity [GO:0003824]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]
d2c8cc__d2j3ze1__1			Firmicutes	Firmicutes		extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]		
d2c8db__d2c8ee___1					extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	transferase activity, transferring pentosyl groups [GO:0016763]	transferase activity, transferring pentosyl groups [GO:0016763]
d2c8dc__d4h0ta1__1		Metazoa		Chordata	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	extracellular region [GO:0005576]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	transferase activity, transferring pentosyl groups [GO:0016763]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2c8fe__d5bwmb___1		Metazoa		Chordata	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	extracellular region [GO:0005576]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	transferase activity, transferring pentosyl groups [GO:0016763]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d2c8ga__d1uk1a2__1		Metazoa		Chordata	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	transferase activity, transferring pentosyl groups [GO:0016763]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2c8gc__d4rv6c2__1		Metazoa		Chordata	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	transferase activity, transferring pentosyl groups [GO:0016763]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2c8gd__d4hhzd2__1		Metazoa		Chordata	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	transferase activity, transferring pentosyl groups [GO:0016763]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2c8ha__d3c49a2__1		Metazoa		Chordata	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; catalytic activity [GO:0003824]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	extracellular region [GO:0005576]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]	transferase activity, transferring pentosyl groups [GO:0016763]	catalytic activity [GO:0003824]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]
d2c8hc__d1wokc2__1		Metazoa		Chordata	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	transferase activity, transferring pentosyl groups [GO:0016763]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2c8hd__d4undb2__1		Metazoa		Chordata	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	transferase activity, transferring pentosyl groups [GO:0016763]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2c8ia1_d1f8v.2__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]
d2c8ja__d2xvza___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]	periplasmic space [GO:0042597]; cobalt ion binding [GO:0050897]; heme binding [GO:0020037]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; sirohydrochlorin ferrochelatase activity [GO:0051266]; anaerobic cobalamin biosynthetic process [GO:0019251]; protein tetramerization [GO:0051262]	heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]	anaerobic cobalamin biosynthetic process [GO:0019251]; protein tetramerization [GO:0051262]	cytoplasm [GO:0005737]	periplasmic space [GO:0042597]	ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]	cobalt ion binding [GO:0050897]; heme binding [GO:0020037]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; sirohydrochlorin ferrochelatase activity [GO:0051266]
d2c8jb__d2hrec___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cytoplasm [GO:0005737]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d2c8ka4_d2a29a___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium ion-transporting ATPase complex [GO:0031004]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; potassium transmembrane transporter activity, phosphorylative mechanism [GO:0008556]; cation transmembrane transport [GO:0098655]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]	calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	cation transmembrane transport [GO:0098655]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium ion-transporting ATPase complex [GO:0031004]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; potassium transmembrane transporter activity, phosphorylative mechanism [GO:0008556]
d2c8ne2_d1fp8a___1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	alpha-L-arabinofuranosidase activity [GO:0046556]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]
d2c8ua1_d3vk9c2__1	Metazoa	Metazoa	Platyhelminthes	Arthropoda	glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]					glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d2c8ua2_d1auca___1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]		activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	glutathione transferase activity [GO:0004364]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d2c91b__d4xapa___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; phenanthrene-9,10-epoxide hydrolase activity [GO:0019119]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]		alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; phenanthrene-9,10-epoxide hydrolase activity [GO:0019119]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2c91c__d3wbwa___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; phenanthrene-9,10-epoxide hydrolase activity [GO:0019119]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]		alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; phenanthrene-9,10-epoxide hydrolase activity [GO:0019119]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2c9pc__d2k7qa2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	periplasmic space [GO:0042597]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	copper ion binding [GO:0005507]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d2c9ta__d1ux2g___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2c9te__d5lxba___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2c9te__d5ougb___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d2c9ua__d2e47a___1	Metazoa	Metazoa	Chordata	Arthropoda	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]		chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2ca6a__d1a4yd___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; GTPase activator activity [GO:0005096]; positive regulation of protein export from nucleus [GO:0046827]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	positive regulation of protein export from nucleus [GO:0046827]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	GTPase activator activity [GO:0005096]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]
d2ca6b__d1fqvk2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; GTPase activator activity [GO:0005096]; positive regulation of protein export from nucleus [GO:0046827]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]; cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	positive regulation of protein export from nucleus [GO:0046827]	cellular iron ion homeostasis [GO:0006879]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H2A monoubiquitination [GO:0035518]; interleukin-1-mediated signaling pathway [GO:0070498]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; NIK/NF-kappaB signaling [GO:0038061]; post-translational protein modification [GO:0043687]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle phase transition [GO:1901990]; SCF complex assembly [GO:0010265]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cell [GO:0005623]; centrosome [GO:0005813]; Cul7-RING ubiquitin ligase complex [GO:0031467]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	GTPase activator activity [GO:0005096]	beta-catenin binding [GO:0008013]; cullin family protein binding [GO:0097602]; protein domain specific binding [GO:0019904]; ubiquitin-protein transferase activity [GO:0004842]
d2ca9b2_d3dhxa1__1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; Gram-negative-bacterium-type cell wall [GO:0009276]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATPase-coupled transmembrane transporter activity [GO:0042626]; D-methionine transmembrane transporter activity [GO:0048474]; L-methionine transmembrane transporter activity [GO:0015191]; D-methionine transport [GO:0048473]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	D-methionine transport [GO:0048473]	protein-DNA complex [GO:0032993]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; Gram-negative-bacterium-type cell wall [GO:0009276]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; D-methionine transmembrane transporter activity [GO:0048474]; L-methionine transmembrane transporter activity [GO:0015191]
d2cada2_d2bj7a2__1			Proteobacteria	Euryarchaeota	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nickel cation binding [GO:0016151]; response to nickel cation [GO:0010045]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	response to nickel cation [GO:0010045]	protein-DNA complex [GO:0032993]		DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nickel cation binding [GO:0016151]
d2caia2_d1oyja2__1	Metazoa	Viridiplantae	Platyhelminthes	Streptophyta	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]		glutathione metabolic process [GO:0006749]		cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2cala__d3n2jj___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2cama__d4bj8k___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]; antibacterial humoral response [GO:0019731]	biotin binding [GO:0009374]	antibacterial humoral response [GO:0019731]		extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2cana__d4oytb___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]		ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d2canb__d3fq7a___1	Metazoa		Chordata	Cyanobacteria	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d2caqa1_d3f63a2__1	Metazoa	Metazoa	Platyhelminthes	Arthropoda	glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]					glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d2cara1_d4p0ub___1	Metazoa		Chordata		cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; dITP diphosphatase activity [GO:0035870]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; chromosome organization [GO:0051276]; deoxyribonucleoside triphosphate catabolic process [GO:0009204]; ITP catabolic process [GO:0006193]; nucleoside triphosphate catabolic process [GO:0009143]; purine nucleotide catabolic process [GO:0006195]		chromosome organization [GO:0051276]; deoxyribonucleoside triphosphate catabolic process [GO:0009204]; ITP catabolic process [GO:0006193]; nucleoside triphosphate catabolic process [GO:0009143]; purine nucleotide catabolic process [GO:0006195]		cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]		dITP diphosphatase activity [GO:0035870]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]	
d2caua1_d1j3ra___1	Viridiplantae		Streptophyta	Euryarchaeota	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	protein homotrimerization [GO:0070207]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]
d2cazb1_d2f6md___1	Fungi	Fungi	Ascomycota	Ascomycota	endosome [GO:0005768]; ESCRT I complex [GO:0000813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; nucleus [GO:0005634]; ATP export [GO:1904669]; endosome transport via multivesicular body sorting pathway [GO:0032509]; protein targeting to membrane [GO:0006612]; protein targeting to vacuole [GO:0006623]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome [GO:0005768]; ESCRT I complex [GO:0000813]; late endosome membrane [GO:0031902]; ubiquitin binding [GO:0043130]; ATP export [GO:1904669]; cellular protein modification process [GO:0006464]; late endosome to vacuole transport [GO:0045324]; negative regulation of protein polyubiquitination [GO:1902915]; protein targeting to membrane [GO:0006612]; protein targeting to vacuole [GO:0006623]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	ATP export [GO:1904669]; endosome transport via multivesicular body sorting pathway [GO:0032509]; protein targeting to membrane [GO:0006612]; protein targeting to vacuole [GO:0006623]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	ATP export [GO:1904669]; cellular protein modification process [GO:0006464]; late endosome to vacuole transport [GO:0045324]; negative regulation of protein polyubiquitination [GO:1902915]; protein targeting to membrane [GO:0006612]; protein targeting to vacuole [GO:0006623]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	endosome [GO:0005768]; ESCRT I complex [GO:0000813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; nucleus [GO:0005634]	cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endosome [GO:0005768]; ESCRT I complex [GO:0000813]; late endosome membrane [GO:0031902]		ubiquitin binding [GO:0043130]
d2cb3d__d3ng4d___1	Metazoa	Metazoa	Arthropoda	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; peptidoglycan receptor activity [GO:0016019]; zinc ion binding [GO:0008270]; antimicrobial humoral response [GO:0019730]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of natural killer cell differentiation involved in immune response [GO:0032827]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of innate immune response [GO:0045089]; positive regulation of phagocytosis [GO:0050766]	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of natural killer cell differentiation involved in immune response [GO:0032827]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of innate immune response [GO:0045089]; positive regulation of phagocytosis [GO:0050766]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; peptidoglycan receptor activity [GO:0016019]; zinc ion binding [GO:0008270]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]
d2cb8a__d1acaa___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; perinuclear endoplasmic reticulum [GO:0097038]; benzodiazepine receptor binding [GO:0030156]; lipid binding [GO:0008289]; long-chain fatty acyl-CoA binding [GO:0036042]; protein dimerization activity [GO:0046983]; acyl-CoA metabolic process [GO:0006637]; phosphatidylcholine acyl-chain remodeling [GO:0036151]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	acyl-CoA metabolic process [GO:0006637]; phosphatidylcholine acyl-chain remodeling [GO:0036151]		endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; perinuclear endoplasmic reticulum [GO:0097038]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]	benzodiazepine receptor binding [GO:0030156]; lipid binding [GO:0008289]; long-chain fatty acyl-CoA binding [GO:0036042]; protein dimerization activity [GO:0046983]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]
d2cbba__d2nn1a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]
d2cbea__d3dvda___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2cbia1_d2choa1__1			Firmicutes	Bacteroidetes	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]
d2cbia2_d1gqib1__1			Firmicutes	Proteobacteria	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	glucuronoxylan catabolic process [GO:2000886]		cell outer membrane [GO:0009279]; extracellular region [GO:0005576]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]
d2cbib2_d1jd9a2__1			Firmicutes	Proteobacteria	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d2cbjb1_d2jiwb1__1			Firmicutes	Bacteroidetes	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]
d2cbna1_d2ohig1__1			Proteobacteria	Euryarchaeota	3'-tRNA processing endoribonuclease activity [GO:0042781]; endoribonuclease activity, producing 5'-phosphomonoesters [GO:0016891]; exoribonuclease activity [GO:0004532]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; zinc ion binding [GO:0008270]; tRNA processing [GO:0008033]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	tRNA processing [GO:0008033]				3'-tRNA processing endoribonuclease activity [GO:0042781]; endoribonuclease activity, producing 5'-phosphomonoesters [GO:0016891]; exoribonuclease activity [GO:0004532]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d2cbpa__d3nsca2__1	Viridiplantae		Streptophyta	Proteobacteria	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d2cbsa__d2akqb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]
d2cbxa2_d2q6ob1__1			Actinobacteria	Actinobacteria	adenosyl-fluoride synthase activity [GO:0033846]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]					adenosyl-fluoride synthase activity [GO:0033846]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]
d2cbza1_d4p33a___1	Metazoa		Chordata	Proteobacteria	basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ABC-type transmembrane transporter activity [GO:0140359]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled glutathione S-conjugate transmembrane transporter activity [GO:0015431]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATPase-coupled vitamin B12 transmembrane transporter activity [GO:0015420]; ATPase-coupled xenobiotic transmembrane transporter activity [GO:0008559]; efflux transmembrane transporter activity [GO:0015562]; glutathione transmembrane transporter activity [GO:0034634]; xenobiotic transmembrane transporter activity [GO:0042910]; cell chemotaxis [GO:0060326]; cellular response to amyloid-beta [GO:1904646]; cobalamin metabolic process [GO:0009235]; drug transmembrane transport [GO:0006855]; export across plasma membrane [GO:0140115]; glutathione transmembrane transport [GO:0034775]; leukotriene metabolic process [GO:0006691]; leukotriene transport [GO:0071716]; phospholipid translocation [GO:0045332]; positive regulation of inflammatory response [GO:0050729]; response to drug [GO:0042493]; sphingolipid translocation [GO:0099039]; transepithelial transport [GO:0070633]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; lipopolysaccharide floppase activity [GO:0015437]; protein-containing complex binding [GO:0044877]; lipopolysaccharide transport [GO:0015920]; transmembrane transport [GO:0055085]	cell chemotaxis [GO:0060326]; cellular response to amyloid-beta [GO:1904646]; cobalamin metabolic process [GO:0009235]; drug transmembrane transport [GO:0006855]; export across plasma membrane [GO:0140115]; glutathione transmembrane transport [GO:0034775]; leukotriene metabolic process [GO:0006691]; leukotriene transport [GO:0071716]; phospholipid translocation [GO:0045332]; positive regulation of inflammatory response [GO:0050729]; response to drug [GO:0042493]; sphingolipid translocation [GO:0099039]; transepithelial transport [GO:0070633]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908]	lipopolysaccharide transport [GO:0015920]; transmembrane transport [GO:0055085]	basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	ABC-type transmembrane transporter activity [GO:0140359]; ATPase activity [GO:0016887]; ATPase-coupled glutathione S-conjugate transmembrane transporter activity [GO:0015431]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATPase-coupled vitamin B12 transmembrane transporter activity [GO:0015420]; ATPase-coupled xenobiotic transmembrane transporter activity [GO:0008559]; ATP binding [GO:0005524]; efflux transmembrane transporter activity [GO:0015562]; glutathione transmembrane transporter activity [GO:0034634]; xenobiotic transmembrane transporter activity [GO:0042910]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; lipopolysaccharide floppase activity [GO:0015437]; protein-containing complex binding [GO:0044877]
d2cc0a1_d1w1b1___1			Actinobacteria	Firmicutes	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]; sporulation resulting in formation of a cellular spore [GO:0030435]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]; sporulation resulting in formation of a cellular spore [GO:0030435]			hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]
d2cc2c1_d5b6ia2__1			Actinobacteria	Actinobacteria	adenosyl-fluoride synthase activity [GO:0033846]	adenosyl-fluoride synthase activity [GO:0033846]					adenosyl-fluoride synthase activity [GO:0033846]	adenosyl-fluoride synthase activity [GO:0033846]
d2cc3a1_d2xrxv___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type IV secretion system complex [GO:0043684]; identical protein binding [GO:0042802]; protein secretion by the type IV secretion system [GO:0030255]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	protein secretion by the type IV secretion system [GO:0030255]	aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type IV secretion system complex [GO:0043684]		identical protein binding [GO:0042802]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2cc8a__d2vxah___1			Euryarchaeota	Proteobacteria	cytosol [GO:0005829]	nucleotide binding [GO:0000166]			cytosol [GO:0005829]			nucleotide binding [GO:0000166]
d2ccab2_d1cvua1__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d2ccdb1_d3atjb1__1		Viridiplantae	Actinobacteria	Streptophyta	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; vacuole [GO:0005773]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2ccdb2_d1s6vc___1		Fungi	Actinobacteria	Ascomycota	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2cchb1_d4cfnb2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2ccib2_d3blqb2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2ccib2_d4bcgb2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2ccid1_d2wipd2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2ccma__d1k96a___1	Metazoa	Metazoa	Mollusca	Chordata	metal ion binding [GO:0046872]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; ion transmembrane transporter activity [GO:0015075]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tropomyosin binding [GO:0005523]; zinc ion binding [GO:0008270]; axonogenesis [GO:0007409]; positive regulation of fibroblast proliferation [GO:0048146]; signal transduction [GO:0007165]		axonogenesis [GO:0007409]; positive regulation of fibroblast proliferation [GO:0048146]; signal transduction [GO:0007165]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]	metal ion binding [GO:0046872]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; ion transmembrane transporter activity [GO:0015075]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tropomyosin binding [GO:0005523]; zinc ion binding [GO:0008270]
d2ccma__d1xk4l___1	Metazoa	Metazoa	Mollusca	Chordata	metal ion binding [GO:0046872]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]		cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	metal ion binding [GO:0046872]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d2ccmb__d2khna1__1	Metazoa	Metazoa	Mollusca	Chordata	metal ion binding [GO:0046872]	apical dendrite [GO:0097440]; calyx of Held [GO:0044305]; cell junction [GO:0030054]; clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endocytic vesicle [GO:0030139]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; postsynaptic actin cytoskeleton [GO:0098871]; presynaptic endocytic zone [GO:0098833]; recycling endosome [GO:0055037]; calcium ion binding [GO:0005509]; guanyl-nucleotide exchange factor activity [GO:0005085]; kinase activator activity [GO:0019209]; molecular adaptor activity [GO:0060090]; proline-rich region binding [GO:0070064]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; brain development [GO:0007420]; cellular protein localization [GO:0034613]; ephrin receptor signaling pathway [GO:0048013]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; membrane organization [GO:0061024]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of apoptotic process [GO:0043065]; positive regulation of caveolin-mediated endocytosis [GO:2001288]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of protein kinase B signaling [GO:0051897]; protein transport [GO:0015031]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle endocytosis [GO:0048488]; viral process [GO:0016032]		brain development [GO:0007420]; cellular protein localization [GO:0034613]; ephrin receptor signaling pathway [GO:0048013]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; membrane organization [GO:0061024]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of apoptotic process [GO:0043065]; positive regulation of caveolin-mediated endocytosis [GO:2001288]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of protein kinase B signaling [GO:0051897]; protein transport [GO:0015031]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle endocytosis [GO:0048488]; viral process [GO:0016032]		apical dendrite [GO:0097440]; calyx of Held [GO:0044305]; cell junction [GO:0030054]; clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endocytic vesicle [GO:0030139]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; postsynaptic actin cytoskeleton [GO:0098871]; presynaptic endocytic zone [GO:0098833]; recycling endosome [GO:0055037]	metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; guanyl-nucleotide exchange factor activity [GO:0005085]; kinase activator activity [GO:0019209]; molecular adaptor activity [GO:0060090]; proline-rich region binding [GO:0070064]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]
d2ccra1_d1kxtc2__1		Metazoa	Firmicutes	Chordata	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	metabolic process [GO:0008152]	carbohydrate catabolic process [GO:0016052]		extracellular space [GO:0005615]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d2ccra1_d2vi0a___1			Firmicutes	Firmicutes	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	metabolic process [GO:0008152]	cellulose catabolic process [GO:0030245]			arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]
d2ccrb__d1bgmm5__1			Firmicutes		arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]		metabolic process [GO:0008152]				arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]	
d2ccwa__d1kbve2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]	cell outer membrane [GO:0009279]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ccyb__d1e84a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2ccza2_d1asza1__1		Fungi	Proteobacteria	Ascomycota	pre-primosome complex [GO:1990099]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269]; plasmid maintenance [GO:0006276]; response to radiation [GO:0009314]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	DNA replication, synthesis of RNA primer [GO:0006269]; DNA replication initiation [GO:0006270]; plasmid maintenance [GO:0006276]; response to radiation [GO:0009314]	aspartyl-tRNA aminoacylation [GO:0006422]	pre-primosome complex [GO:1990099]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; RNA binding [GO:0003723]
d2cd0a__d2ntsp2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2cd0b__d4jfya1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]	
d2cd7a__d2wmyd___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]	protein tyrosine phosphatase activity [GO:0004725]	response to arsenic-containing substance [GO:0046685]		cytoplasm [GO:0005737]		arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d2cd8b__d2pg7b1__1		Metazoa	Actinobacteria	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d2cdea1_d1zhbb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2cdea2_d4pjad___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2cdee1_d1o0vb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2cdef1_d5m6ac2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2cdfb1_d5ijvc2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2cdgb1_d1j8he2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2cdgb2_d4z77e1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2cdhc2_d2h84b2__1			Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	naringenin-chalcone synthase activity [GO:0016210]; oxidoreductase activity [GO:0016491]; aggregation involved in sorocarp development [GO:0031152]; chemotaxis to cAMP [GO:0043327]; flavonoid biosynthetic process [GO:0009813]; negative regulation of gene expression [GO:0010629]; polyketide biosynthetic process [GO:0030639]; positive regulation of gene expression [GO:0010628]; regulation of cAMP-mediated signaling [GO:0043949]; resorcinol metabolic process [GO:0019505]; signal transduction [GO:0007165]; sorocarp sorus development [GO:0048837]; sorocarp spore cell differentiation [GO:0044671]; sorocarp stalk cell differentiation [GO:0031149]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	aggregation involved in sorocarp development [GO:0031152]; chemotaxis to cAMP [GO:0043327]; flavonoid biosynthetic process [GO:0009813]; negative regulation of gene expression [GO:0010629]; polyketide biosynthetic process [GO:0030639]; positive regulation of gene expression [GO:0010628]; regulation of cAMP-mediated signaling [GO:0043949]; resorcinol metabolic process [GO:0019505]; signal transduction [GO:0007165]; sorocarp sorus development [GO:0048837]; sorocarp spore cell differentiation [GO:0044671]; sorocarp stalk cell differentiation [GO:0031149]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	naringenin-chalcone synthase activity [GO:0016210]; oxidoreductase activity [GO:0016491]
d2cdhe1_d1og8c4__1			Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	
d2cdhf1_d2vb9c1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2cdhg1_d3qwff___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2cdhi1_d5lc1f1__1			Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]
d2cdhj1_d2cvqa1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	L-malate dehydrogenase activity [GO:0030060]
d2cdpa__d1dp0a3__1			Proteobacteria	Proteobacteria	beta-agarase activity [GO:0033916]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-agarase activity [GO:0033916]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2cdsa__d2b6ta___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2cdva__d2newa___1			Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]		anaerobic respiration [GO:0009061]		periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d2cdya1_d3tqjb1__1			Deinococcus-Thermus	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				cytosol [GO:0005829]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2cdyb2_d1dt0a2__1			Deinococcus-Thermus	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2cdyc2_d3ak2a2__1			Deinococcus-Thermus	Crenarchaeota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2ce1a__d1dt1a___1	Viridiplantae		Streptophyta	Deinococcus-Thermus	chloroplast thylakoid lumen [GO:0009543]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem I [GO:0009773]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	photosynthetic electron transport in photosystem I [GO:0009773]		chloroplast thylakoid lumen [GO:0009543]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2ce4a2_d3lj9b2__1			Deinococcus-Thermus	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2ce4b2_d1jr9a2__1			Deinococcus-Thermus	Firmicutes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2ce6a1_d2cgya___1	Metazoa	Metazoa	Mollusca	Mollusca	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]	cell adhesion [GO:0007155]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2ce8a2_d4ukcg___1	Metazoa		Chordata		beta-catenin-TCF complex [GO:1990907]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; identical protein binding [GO:0042802]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; animal organ morphogenesis [GO:0009887]; beta-catenin-TCF complex assembly [GO:1904837]; multicellular organism development [GO:0007275]; negative regulation of anoikis [GO:2000811]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]		animal organ morphogenesis [GO:0009887]; beta-catenin-TCF complex assembly [GO:1904837]; multicellular organism development [GO:0007275]; negative regulation of anoikis [GO:2000811]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]		beta-catenin-TCF complex [GO:1990907]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]		identical protein binding [GO:0042802]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]	
d2ce8c2_d2b5lb1__1	Metazoa	Metazoa	Chordata	Chordata	beta-catenin-TCF complex [GO:1990907]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; identical protein binding [GO:0042802]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; animal organ morphogenesis [GO:0009887]; beta-catenin-TCF complex assembly [GO:1904837]; multicellular organism development [GO:0007275]; negative regulation of anoikis [GO:2000811]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; Cul4A-RING E3 ubiquitin ligase complex [GO:0031464]; Cul4B-RING E3 ubiquitin ligase complex [GO:0031465]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cullin family protein binding [GO:0097602]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; protein binding, bridging [GO:0030674]; protein-containing complex binding [GO:0044877]; WD40-repeat domain binding [GO:0071987]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; histone H2A monoubiquitination [GO:0035518]; interaction with symbiont [GO:0051702]; negative regulation of apoptotic process [GO:0043066]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral release from host cell [GO:1902188]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of mitotic cell cycle phase transition [GO:1901990]; rhythmic process [GO:0048511]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	animal organ morphogenesis [GO:0009887]; beta-catenin-TCF complex assembly [GO:1904837]; multicellular organism development [GO:0007275]; negative regulation of anoikis [GO:2000811]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; histone H2A monoubiquitination [GO:0035518]; interaction with symbiont [GO:0051702]; negative regulation of apoptotic process [GO:0043066]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral release from host cell [GO:1902188]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of mitotic cell cycle phase transition [GO:1901990]; rhythmic process [GO:0048511]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	beta-catenin-TCF complex [GO:1990907]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	Cul4A-RING E3 ubiquitin ligase complex [GO:0031464]; Cul4B-RING E3 ubiquitin ligase complex [GO:0031465]; Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]	cullin family protein binding [GO:0097602]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; protein binding, bridging [GO:0030674]; protein-containing complex binding [GO:0044877]; WD40-repeat domain binding [GO:0071987]
d2ce8d2_d2g99a___1	Metazoa	Metazoa	Chordata	Chordata	beta-catenin-TCF complex [GO:1990907]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; identical protein binding [GO:0042802]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; animal organ morphogenesis [GO:0009887]; beta-catenin-TCF complex assembly [GO:1904837]; multicellular organism development [GO:0007275]; negative regulation of anoikis [GO:2000811]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	animal organ morphogenesis [GO:0009887]; beta-catenin-TCF complex assembly [GO:1904837]; multicellular organism development [GO:0007275]; negative regulation of anoikis [GO:2000811]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	beta-catenin-TCF complex [GO:1990907]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	identical protein binding [GO:0042802]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]
d2ce9c2_d4ujuh___1	Metazoa		Chordata		beta-catenin-TCF complex [GO:1990907]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; identical protein binding [GO:0042802]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; animal organ morphogenesis [GO:0009887]; beta-catenin-TCF complex assembly [GO:1904837]; multicellular organism development [GO:0007275]; negative regulation of anoikis [GO:2000811]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]		animal organ morphogenesis [GO:0009887]; beta-catenin-TCF complex assembly [GO:1904837]; multicellular organism development [GO:0007275]; negative regulation of anoikis [GO:2000811]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]		beta-catenin-TCF complex [GO:1990907]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]		identical protein binding [GO:0042802]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]	
d2ceia__d4toad___1	Metazoa		Chordata	Proteobacteria	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2cejb__d4z50c___1					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d2cela__d2dvfb___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2cemb__d5ozza___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d2ceqa__d3dhpa2__1		Metazoa	Crenarchaeota	Chordata	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d2cevc__d3ewfa___1		Metazoa	Firmicutes	Chordata	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]		cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]	histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]
d2cevc__d4ixua___1		Metazoa	Firmicutes	Chordata	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d2cevd__d1gq7a___1			Firmicutes	Actinobacteria	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	metal ion binding [GO:0046872]; proclavaminate amidinohydrolase activity [GO:0033972]; clavulanic acid biosynthetic process [GO:0033050]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	clavulanic acid biosynthetic process [GO:0033050]			arginase activity [GO:0004053]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; proclavaminate amidinohydrolase activity [GO:0033972]
d2ceve__d4hzec___1		Metazoa	Firmicutes	Chordata	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d2cevf__d3nipc___1			Firmicutes	Proteobacteria	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]			arginase activity [GO:0004053]; metal ion binding [GO:0046872]	agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]
d2cf2a1_d2wl4d2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2cf2a2_d1m1ob1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2cf2j1_d2wkta2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2cf2j2_d4ls6a2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d2cf2l1_d1yoca1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	
d2cf7c__d4to9a___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2cf7d__d3oj5c___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d2cf7e__d3b3hb___1			Firmicutes		cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	
d2cf7f__d1mfrb___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2cf7g__d3uoii___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2cf7h__d2jd68___1			Firmicutes	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d2cf7j__d2jd75___1			Firmicutes	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d2cf7k__d5jkke___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2cf7l__d4toao___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2cfga2_d1a2vd2__1		Fungi	Actinobacteria	Ascomycota	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	peroxisome [GO:0005777]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]		peroxisome [GO:0005777]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d2cfgb2_d1a2va2__1		Fungi	Actinobacteria	Ascomycota	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	peroxisome [GO:0005777]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]		peroxisome [GO:0005777]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d2cfha__d5jruc___1	Metazoa		Chordata	Firmicutes	cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; trans-Golgi network [GO:0005802]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; nervous system development [GO:0007399]; regulation of GTPase activity [GO:0043087]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; nervous system development [GO:0007399]; regulation of GTPase activity [GO:0043087]	signal transduction [GO:0007165]	cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; trans-Golgi network [GO:0005802]	integral component of membrane [GO:0016021]		heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2cfhb__d3nvua___1	Metazoa		Chordata	Firmicutes	cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; trans-Golgi network [GO:0005802]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; nervous system development [GO:0007399]; regulation of GTPase activity [GO:0043087]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; nervous system development [GO:0007399]; regulation of GTPase activity [GO:0043087]	signal transduction [GO:0007165]	cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; trans-Golgi network [GO:0005802]	integral component of membrane [GO:0016021]		heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2cfwa3_d2w0qa2__1			Actinobacteria	Proteobacteria	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	periplasmic space [GO:0042597]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]		periplasmic space [GO:0042597]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d2cfxb2_d3zo7a___1			Firmicutes	Actinobacteria	DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]		beta-ketoadipate pathway [GO:0042952]			DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	muconolactone delta-isomerase activity [GO:0016159]
d2cfxe2_d3znuf___1			Firmicutes	Actinobacteria	DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]		beta-ketoadipate pathway [GO:0042952]			DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	muconolactone delta-isomerase activity [GO:0016159]
d2cfxg2_d4wwsa___1			Firmicutes	Firmicutes	DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]					DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2cg0a2_d1ekmb2__1		Fungi	Actinobacteria	Ascomycota	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	peroxisome [GO:0005777]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]		peroxisome [GO:0005777]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d2cg2a2_d4ua4a___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; alkyl sulfatase activity [GO:0018741]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]; dodecyl sulfate metabolic process [GO:0018909]	metal ion binding [GO:0046872]	dodecyl sulfate metabolic process [GO:0018909]		outer membrane-bounded periplasmic space [GO:0030288]		alkyl sulfatase activity [GO:0018741]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	metal ion binding [GO:0046872]
d2cg5b__d4mrtc1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]; lysine biosynthetic process via aminoadipic acid [GO:0019878]; pantothenate metabolic process [GO:0015939]	holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]; antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]; lysine biosynthetic process via aminoadipic acid [GO:0019878]; positive regulation of single-species biofilm formation [GO:1900192]	lysine biosynthetic process via aminoadipic acid [GO:0019878]; pantothenate metabolic process [GO:0015939]	antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]; lysine biosynthetic process via aminoadipic acid [GO:0019878]; positive regulation of single-species biofilm formation [GO:1900192]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]	holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]
d2cgab__d2z3da___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2cggb__d1v3xa___1		Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d2cgia1_d1ckha___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2cgrh1_d1mrcl1__1	Metazoa		Chordata									
d2cgrh1_d4amkl2__1	Metazoa		Chordata									
d2cgrh2_d4enef1__1	Metazoa		Chordata	Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d2cgrl1_d1gm3l1__1	Metazoa		Chordata									
d2ch1a1_d2fnia___1	Metazoa		Arthropoda	Proteobacteria	peroxisome [GO:0005777]; alanine-glyoxylate transaminase activity [GO:0008453]; serine-pyruvate transaminase activity [GO:0004760]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; polysaccharide biosynthetic process [GO:0000271]	glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]	polysaccharide biosynthetic process [GO:0000271]	peroxisome [GO:0005777]		alanine-glyoxylate transaminase activity [GO:0008453]; serine-pyruvate transaminase activity [GO:0004760]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d2ch2a__d4n0wc___1	Metazoa		Arthropoda	Proteobacteria	peroxisome [GO:0005777]; alanine-glyoxylate transaminase activity [GO:0008453]; serine-pyruvate transaminase activity [GO:0004760]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]	alanine-glyoxylate transaminase activity [GO:0008453]; serine-pyruvate transaminase activity [GO:0004760]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d2ch4b1_d2qdla1__1			Thermotogae	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]; chemotaxis [GO:0006935]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]	
d2ch4y1_d1b3qa2__1			Thermotogae	Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]; chemotaxis [GO:0006935]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]; chemotaxis [GO:0006935]	chemotaxis [GO:0006935]	chemotaxis [GO:0006935]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]
d2ch4y1_d2ho9a___1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]; chemotaxis [GO:0006935]	cell [GO:0005623]; cytosol [GO:0005829]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]; protein domain specific binding [GO:0019904]; chemotaxis [GO:0006935]; establishment of localization in cell [GO:0051649]; positive regulation of post-translational protein modification [GO:1901875]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]	chemotaxis [GO:0006935]; establishment of localization in cell [GO:0051649]; positive regulation of post-translational protein modification [GO:1901875]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]	protein domain specific binding [GO:0019904]
d2ch6a1_d4mlea1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]
d2ch6d2_d1huxa___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; metal ion binding [GO:0046872]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]	N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d2ch6d2_d2gtdf1__1	Metazoa		Chordata	Thermotogae	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	coenzyme A biosynthetic process [GO:0015937]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d2chbg__d4dxfa1__1			Proteobacteria	Firmicutes	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	pathogenesis [GO:0009405]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	
d2chca1_d4xdvh___1			Actinobacteria	Actinobacteria		limonene-1,2-epoxide hydrolase activity [GO:0018744]						limonene-1,2-epoxide hydrolase activity [GO:0018744]
d2chfa__d3lteg1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]		metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d2chha__d2bp6b___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]		single-species biofilm formation [GO:0044010]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2chia__d1mrrb___1	Metazoa		Chordata	Proteobacteria	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2chia__d3mpsi1__1	Metazoa		Chordata	Euryarchaeota	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2choa2_d2exoa___1			Bacteroidetes	Actinobacteria	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]
d2chob2_d3dypa3__1			Bacteroidetes	Proteobacteria	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2chpa__d3ak8h___1			Firmicutes		cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	
d2chpa__d5l89s___1			Firmicutes	Proteobacteria	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]
d2chpc__d3uoiu___1			Firmicutes	Actinobacteria	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2chra2_d3r25h1__1			Proteobacteria	Proteobacteria	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]	cellular amino acid catabolic process [GO:0009063]			chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]	magnesium ion binding [GO:0000287]
d2chsa__d1odea___1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	chorismate mutase activity [GO:0004106]	chorismate mutase activity [GO:0004106]
d2chsd__d1nq3c___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	mitochondrial matrix [GO:0005759]; nucleus [GO:0005634]; peroxisome [GO:0005777]; deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; mRNA binding [GO:0003729]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; nucleus [GO:0005634]; peroxisome [GO:0005777]	chorismate mutase activity [GO:0004106]	deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; mRNA binding [GO:0003729]
d2chta__d5v4da1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	metal ion binding [GO:0046872]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		cytoplasm [GO:0005737]		chorismate mutase activity [GO:0004106]	metal ion binding [GO:0046872]
d2chtf__d3r0pa___1			Firmicutes		cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		cytoplasm [GO:0005737]		chorismate mutase activity [GO:0004106]	
d2chti__d1onic___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]; deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; L-threonine catabolic process to glycine [GO:0019518]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; L-threonine catabolic process to glycine [GO:0019518]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]	chorismate mutase activity [GO:0004106]	deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d2chtj__d1jd1d___1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	organonitrogen compound catabolic process [GO:1901565]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	chorismate mutase activity [GO:0004106]	deaminase activity [GO:0019239]
d2ci4a__d5n0ya3__1	Metazoa	Metazoa	Chordata	Chordata	amino acid binding [GO:0016597]; dimethylargininase activity [GO:0016403]; zinc ion binding [GO:0008270]; arginine catabolic process [GO:0006527]; arginine metabolic process [GO:0006525]; citrulline metabolic process [GO:0000052]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of vascular permeability [GO:0043116]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein nitrosylation [GO:0017014]; regulation of systemic arterial blood pressure [GO:0003073]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; arginine binding [GO:0034618]; arginine deiminase activity [GO:0016990]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular protein modification process [GO:0006464]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; innate immune response [GO:0045087]; nucleosome assembly [GO:0006334]; protein citrullination [GO:0018101]; stem cell population maintenance [GO:0019827]	arginine catabolic process [GO:0006527]; arginine metabolic process [GO:0006525]; citrulline metabolic process [GO:0000052]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of vascular permeability [GO:0043116]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein nitrosylation [GO:0017014]; regulation of systemic arterial blood pressure [GO:0003073]	cellular protein modification process [GO:0006464]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; innate immune response [GO:0045087]; nucleosome assembly [GO:0006334]; protein citrullination [GO:0018101]; stem cell population maintenance [GO:0019827]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	amino acid binding [GO:0016597]; dimethylargininase activity [GO:0016403]; zinc ion binding [GO:0008270]	arginine binding [GO:0034618]; arginine deiminase activity [GO:0016990]; calcium ion binding [GO:0005509]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]
d2ci5a__d1s9rb___1	Metazoa		Chordata	Tenericutes	amino acid binding [GO:0016597]; dimethylargininase activity [GO:0016403]; zinc ion binding [GO:0008270]; arginine catabolic process [GO:0006527]; arginine metabolic process [GO:0006525]; citrulline metabolic process [GO:0000052]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of vascular permeability [GO:0043116]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein nitrosylation [GO:0017014]; regulation of systemic arterial blood pressure [GO:0003073]	cytoplasm [GO:0005737]; arginine deiminase activity [GO:0016990]; arginine catabolic process to ornithine [GO:0019547]	arginine catabolic process [GO:0006527]; arginine metabolic process [GO:0006525]; citrulline metabolic process [GO:0000052]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of vascular permeability [GO:0043116]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein nitrosylation [GO:0017014]; regulation of systemic arterial blood pressure [GO:0003073]	arginine catabolic process to ornithine [GO:0019547]		cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; dimethylargininase activity [GO:0016403]; zinc ion binding [GO:0008270]	arginine deiminase activity [GO:0016990]
d2ciga__d3jwfb1__1			Actinobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d2ciga__d3srsx___1			Actinobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d2ciia1_d3nacl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2ciia2_d4nqda1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2cika1_d4imla2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2cita1_d1kxqc2__1		Metazoa	Firmicutes	Chordata	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	cellulose catabolic process [GO:0030245]	carbohydrate catabolic process [GO:0016052]		extracellular space [GO:0005615]	cellulase activity [GO:0008810]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d2ciza2_d2cpoa1__1	Fungi	Fungi	Ascomycota	Ascomycota	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]					chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]
d2cj1a1_d2cj2a2__1	Fungi	Fungi	Ascomycota	Ascomycota	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]					chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]
d2cj1a2_d1cpoa1__1	Fungi	Fungi	Ascomycota	Ascomycota	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]					chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]	chloride peroxidase activity [GO:0016691]; metal ion binding [GO:0046872]
d2cj3a__d3t71b1__1		Fungi	Cyanobacteria	Basidiomycota	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]			thylakoid membrane [GO:0042651]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2cj3b__d2uxfa___1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2cj3b__d2zonc1__1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	thylakoid membrane [GO:0042651]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2cjca__d2devc___1			Euryarchaeota	Deinococcus-Thermus	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]						metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	
d2cjfd__d5ydbc___1			Actinobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d2cjfe__d4kiui___1			Actinobacteria	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]		cytosol [GO:0005829]	3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d2cjfe__d5ydbb___1			Actinobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d2cjfg__d3n7ad___1			Actinobacteria	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]		cytosol [GO:0005829]	3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d2cjfi__d3n7an___1			Actinobacteria	Actinobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]		cytosol [GO:0005829]	3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d2cjlb__d4ow1x___1			Actinobacteria	Actinobacteria	chitinase activity [GO:0004568]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]		extracellular region [GO:0005576]	chitinase activity [GO:0004568]; metal ion binding [GO:0046872]	hydrolase activity [GO:0016787]
d2cjmb2_d2whbd1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2cjrb__d2ge8b___1					host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; host cell perinuclear region of cytoplasm [GO:0044220]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]			host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; host cell perinuclear region of cytoplasm [GO:0044220]; viral nucleocapsid [GO:0019013]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; viral nucleocapsid [GO:0019013]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d2cjul__d5t5nj1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]; chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2cjvl__d4s10b1__1		Metazoa		Chordata		actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]		actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]		actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]		actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d2ck0h1_d1j1xl___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2ck0h1_d3vxtc1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2ck0l2_d1h8oa2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2ck2b__d3lpwb2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d2ck3a1_d2jj2h3__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2ck3a2_d3a5cm1__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2ck3b2_d4asue1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2ck3c1_d2f43a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial envelope [GO:0005740]; mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP biosynthetic process [GO:0006754]; ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; cellular response to nitric oxide [GO:0071732]; oxidative phosphorylation [GO:0006119]	ATP synthesis coupled proton transport [GO:0015986]	ATP biosynthetic process [GO:0006754]; ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; cellular response to nitric oxide [GO:0071732]; oxidative phosphorylation [GO:0006119]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial envelope [GO:0005740]; mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2ck3d2_d3ziak1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2ck3d2_d5ik2l1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2ck3f2_d3a5ca1__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2ck9c__d3li1b___1				Euryarchaeota		orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]				orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2ck9e__d2wjzc___1				Thermotogae		cytoplasm [GO:0005737]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; histidine biosynthetic process [GO:0000105]		histidine biosynthetic process [GO:0000105]		cytoplasm [GO:0005737]		imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]
d2ckbb1_d4m7kl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2ckbb2_d4pj5e1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ckbh2_d4z78g1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ckbm__d1op5m1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2ckda1_d1jg1a___1			Actinobacteria	Euryarchaeota	methyltransferase activity [GO:0008168]	cytoplasm [GO:0005737]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]; protein repair [GO:0030091]		protein repair [GO:0030091]		cytoplasm [GO:0005737]	methyltransferase activity [GO:0008168]	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]
d2ckec__d1opja1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]; anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; delta-catenin binding [GO:0070097]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; B cell proliferation [GO:0042100]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; integrin-mediated signaling pathway [GO:0007229]; microspike assembly [GO:0030035]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of cellular senescence [GO:2000772]; regulation of extracellular matrix organization [GO:1903053]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation [GO:0042100]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; integrin-mediated signaling pathway [GO:0007229]; microspike assembly [GO:0030035]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of cellular senescence [GO:2000772]; regulation of extracellular matrix organization [GO:1903053]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; delta-catenin binding [GO:0070097]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]
d2ckfa1_d2hmma1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]	dioxygenase activity [GO:0051213]
d2ckfb__d5wipa___1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	integral component of membrane [GO:0016021]; protein secretion by the type IV secretion system [GO:0030255]	cellular metabolic process [GO:0044237]	protein secretion by the type IV secretion system [GO:0030255]		integral component of membrane [GO:0016021]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]	
d2ckfd__d1w01b___1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	cellular metabolic process [GO:0044237]	steroid metabolic process [GO:0008202]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]	steroid delta-isomerase activity [GO:0004769]
d2ckfe1_d2b1xe1__1			Proteobacteria	Actinobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	cellular metabolic process [GO:0044237]	cellular metabolic process [GO:0044237]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]
d2ckff__d1ogxb___1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	cellular metabolic process [GO:0044237]	steroid metabolic process [GO:0008202]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]	steroid delta-isomerase activity [GO:0004769]
d2ckff__d3i1xa2__1			Proteobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]		cellular metabolic process [GO:0044237]				2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]	
d2ckgb__d2g4dc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; SUMO-specific isopeptidase activity [GO:0070140]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; proteolysis [GO:0006508]; regulation of definitive erythrocyte differentiation [GO:0010724]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; proteolysis [GO:0006508]; regulation of definitive erythrocyte differentiation [GO:0010724]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	endopeptidase activity [GO:0004175]; SUMO-specific isopeptidase activity [GO:0070140]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d2ckra__d5g1mb1__1			Actinobacteria	Proteobacteria	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	cytoplasm [GO:0005737]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]
d2ckrb__d4jcla1__1			Actinobacteria	Firmicutes	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2ckrb__d4pbgb___1			Actinobacteria	Firmicutes	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	6-phospho-beta-galactosidase activity [GO:0033920]; lactose catabolic process via tagatose-6-phosphate [GO:0019512]	cellulose catabolic process [GO:0030245]	lactose catabolic process via tagatose-6-phosphate [GO:0019512]			cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	6-phospho-beta-galactosidase activity [GO:0033920]
d2cksb__d3ueqa1__1			Actinobacteria	Proteobacteria	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	amylosucrase activity [GO:0047669]
d2cl4x1_d1a2ga___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	chloroplast [GO:0009507]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2cl8b1_d4n33c___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d2claa__d1ndib2__1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	response to antibiotic [GO:0046677]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]		endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	chloramphenicol O-acetyltransferase activity [GO:0008811]	carnitine O-acetyltransferase activity [GO:0004092]
d2clpd__d4giea1__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; aldo-keto reductase (NADP) activity [GO:0004033]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; aflatoxin catabolic process [GO:0046223]; cellular aldehyde metabolic process [GO:0006081]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]; prostaglandin biosynthetic process [GO:0001516]	aflatoxin catabolic process [GO:0046223]; cellular aldehyde metabolic process [GO:0006081]; xenobiotic metabolic process [GO:0006805]	prostaglandin biosynthetic process [GO:0001516]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	aldo-keto reductase (NADP) activity [GO:0004033]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2clpg__d4jiix1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; aldo-keto reductase (NADP) activity [GO:0004033]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; aflatoxin catabolic process [GO:0046223]; cellular aldehyde metabolic process [GO:0006081]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular region [GO:0005576]; lysosome [GO:0005764]; mitochondrion [GO:0005739]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; allyl-alcohol dehydrogenase activity [GO:0047655]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; cellular detoxification of aldehyde [GO:0110095]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; retinoid metabolic process [GO:0001523]	aflatoxin catabolic process [GO:0046223]; cellular aldehyde metabolic process [GO:0006081]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of aldehyde [GO:0110095]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; retinoid metabolic process [GO:0001523]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; extracellular region [GO:0005576]; lysosome [GO:0005764]; mitochondrion [GO:0005739]	aldo-keto reductase (NADP) activity [GO:0004033]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; allyl-alcohol dehydrogenase activity [GO:0047655]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d2clpi__d3f7ja___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; aldo-keto reductase (NADP) activity [GO:0004033]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; aflatoxin catabolic process [GO:0046223]; cellular aldehyde metabolic process [GO:0006081]; xenobiotic metabolic process [GO:0006805]	methylglyoxal reductase (NADPH-dependent) activity [GO:0043892]	aflatoxin catabolic process [GO:0046223]; cellular aldehyde metabolic process [GO:0006081]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		aldo-keto reductase (NADP) activity [GO:0004033]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]	methylglyoxal reductase (NADPH-dependent) activity [GO:0043892]
d2clpk__d4r9ob___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; aldo-keto reductase (NADP) activity [GO:0004033]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; aflatoxin catabolic process [GO:0046223]; cellular aldehyde metabolic process [GO:0006081]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; oxidoreductase activity [GO:0016491]	aflatoxin catabolic process [GO:0046223]; cellular aldehyde metabolic process [GO:0006081]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]	aldo-keto reductase (NADP) activity [GO:0004033]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]	oxidoreductase activity [GO:0016491]
d2clrd1_d3fo9l1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2clre2_d1fl6h1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2clsb__d2afif___1	Metazoa		Chordata	Proteobacteria	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; negative regulation of cell adhesion [GO:0007162]; neuron remodeling [GO:0016322]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; Rho protein signal transduction [GO:0007266]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; negative regulation of cell adhesion [GO:0007162]; neuron remodeling [GO:0016322]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; Rho protein signal transduction [GO:0007266]	nitrogen fixation [GO:0009399]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]	molybdenum-iron nitrogenase complex [GO:0016612]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2clta1_d4fvlb2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d2cltb1_d1su3a2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d2cltb2_d1pwpa1__1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d2clva1_d1t7ya1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]
d2clva2_d4y4fa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2clvb__d1q0xl2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2clvp__d3juyf1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2clwb__d5ngza___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K6-linked ubiquitination [GO:0085020]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]	cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]
d2clwc__d4q5ec1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	extracellular space [GO:0005615]; host cell [GO:0043657]; kinase activity [GO:0016301]; pathogenesis [GO:0009405]; protein autophosphorylation [GO:0046777]	cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	pathogenesis [GO:0009405]; protein autophosphorylation [GO:0046777]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	extracellular space [GO:0005615]; host cell [GO:0043657]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	kinase activity [GO:0016301]
d2clwd__d2klya___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein catabolic process [GO:0044257]; cellular response to interferon-beta [GO:0035458]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; protein K48-linked ubiquitination [GO:0070936]; protein N-linked glycosylation via asparagine [GO:0018279]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cellular protein catabolic process [GO:0044257]; cellular response to interferon-beta [GO:0035458]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; protein K48-linked ubiquitination [GO:0070936]; protein N-linked glycosylation via asparagine [GO:0018279]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]
d2clza1_d5k64a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2clzb__d4gsdl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2clzh1_d3eyva1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2clzh2_d3o6fe1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2cm2a2_d1zzwb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; JUN kinase binding [GO:0008432]; MAP kinase phosphatase activity [GO:0033549]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; mitogen-activated protein kinase p38 binding [GO:0048273]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelium regeneration [GO:1905042]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; oligodendrocyte differentiation [GO:0048709]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein dephosphorylation [GO:0006470]; regulation of adaptive immune response [GO:0002819]; regulation of brown fat cell differentiation [GO:0090335]; response to lipopolysaccharide [GO:0032496]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelium regeneration [GO:1905042]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; oligodendrocyte differentiation [GO:0048709]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein dephosphorylation [GO:0006470]; regulation of adaptive immune response [GO:0002819]; regulation of brown fat cell differentiation [GO:0090335]; response to lipopolysaccharide [GO:0032496]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	JUN kinase binding [GO:0008432]; MAP kinase phosphatase activity [GO:0033549]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; mitogen-activated protein kinase p38 binding [GO:0048273]; phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; protein tyrosine phosphatase activity [GO:0004725]
d2cmeg__d2cmea1__1												
d2cmha__d3fuxb___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	cytoplasm [GO:0005737]; 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity [GO:0052908]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	spermidine synthase activity [GO:0004766]	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity [GO:0052908]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]
d2cmha__d3hvjb___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytosol [GO:0005829]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	spermidine synthase activity [GO:0004766]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d2cmhb__d2obfa___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	spermidine synthase activity [GO:0004766]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d2cmla__d4gezj___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2cmna__d3c2wb3__1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]		ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d2cmoa__d1r1nh___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	metal ion binding [GO:0046872]
d2cmya__d3m7ta___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d2cn3b2_d5fkta1__1			Firmicutes	Proteobacteria	cellulosome [GO:0043263]; xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]; cellulose catabolic process [GO:0030245]; xyloglucan catabolic process [GO:2000899]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]; xyloglucan catabolic process [GO:2000899]	carbohydrate metabolic process [GO:0005975]	cellulosome [GO:0043263]		xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2cn4a__d4jetj___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2cn6a__d5lbhd___1	Metazoa		Chordata	Proteobacteria	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2cnda1_d5kswb1__1	Viridiplantae		Streptophyta	Firmicutes	cytosol [GO:0005829]; FAD binding [GO:0071949]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; nitrate reductase (NADH) activity [GO:0009703]; nitrate assimilation [GO:0042128]; nitric oxide biosynthetic process [GO:0006809]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	nitrate assimilation [GO:0042128]; nitric oxide biosynthetic process [GO:0006809]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	FAD binding [GO:0071949]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; nitrate reductase (NADH) activity [GO:0009703]	dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]
d2cnea2_d1g1ha___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2cnea2_d3s4ea1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; JUN kinase phosphatase activity [GO:0008579]; MAP-kinase scaffold activity [GO:0005078]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase activator activity [GO:0030295]; protein kinase inhibitor activity [GO:0004860]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase activity [GO:0045860]; regulation of MAP kinase activity [GO:0043405]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase activity [GO:0045860]; regulation of MAP kinase activity [GO:0043405]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	JUN kinase phosphatase activity [GO:0008579]; MAP-kinase scaffold activity [GO:0005078]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase activator activity [GO:0030295]; protein kinase inhibitor activity [GO:0004860]; protein tyrosine phosphatase activity [GO:0004725]
d2cnpa__d2fcea___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]; calcium ion binding [GO:0005509]; protein N-terminus binding [GO:0047485]	cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; MIH complex [GO:0120155]; myosin II complex [GO:0016460]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; myosin II heavy chain binding [GO:0032038]; myosin V binding [GO:0031489]; actomyosin contractile ring assembly [GO:0000915]; protein localization [GO:0008104]; vesicle targeting [GO:0006903]		actomyosin contractile ring assembly [GO:0000915]; protein localization [GO:0008104]; vesicle targeting [GO:0006903]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nuclear envelope [GO:0005635]	cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; MIH complex [GO:0120155]; myosin II complex [GO:0016460]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; protein N-terminus binding [GO:0047485]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; myosin II heavy chain binding [GO:0032038]; myosin V binding [GO:0031489]
d2cnwb2_d2zs8a___1			Deinococcus-Thermus	Actinobacteria	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	coenzyme A biosynthetic process [GO:0015937]	signal recognition particle [GO:0048500]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d2cnwc2_d1dbsa___1			Deinococcus-Thermus	Proteobacteria	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytosol [GO:0005829]; ATP binding [GO:0005524]; dethiobiotin synthase activity [GO:0004141]; magnesium ion binding [GO:0000287]; biotin biosynthetic process [GO:0009102]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	biotin biosynthetic process [GO:0009102]	signal recognition particle [GO:0048500]	cytosol [GO:0005829]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	ATP binding [GO:0005524]; dethiobiotin synthase activity [GO:0004141]; magnesium ion binding [GO:0000287]
d2cnwc2_d3gj5c___1		Metazoa	Deinococcus-Thermus	Chordata	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	signal recognition particle [GO:0048500]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2cnwd2_d2onjb1__1			Deinococcus-Thermus	Firmicutes	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]		signal recognition particle [GO:0048500]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]
d2cnwe2_d1xrja___1		Metazoa	Deinococcus-Thermus	Chordata	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; uridine kinase activity [GO:0004849]; CTP salvage [GO:0044211]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	CTP salvage [GO:0044211]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]	signal recognition particle [GO:0048500]	cytosol [GO:0005829]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; uridine kinase activity [GO:0004849]
d2cnxa__d2o9ka___1	Metazoa	Metazoa	Chordata	Chordata	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]
d2cnxa__d2ovrb2__1	Metazoa	Metazoa	Chordata	Chordata	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; SCF ubiquitin ligase complex [GO:0019005]; cyclin binding [GO:0030332]; identical protein binding [GO:0042802]; phosphothreonine residue binding [GO:0050816]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lipid homeostasis [GO:0055088]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; post-translational protein modification [GO:0043687]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; regulation of lipid storage [GO:0010883]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lipid homeostasis [GO:0055088]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; post-translational protein modification [GO:0043687]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; regulation of lipid storage [GO:0010883]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; SCF ubiquitin ligase complex [GO:0019005]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]	cyclin binding [GO:0030332]; identical protein binding [GO:0042802]; phosphothreonine residue binding [GO:0050816]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]
d2cnya__d1ut2f___1			Proteobacteria	Proteobacteria		pilus [GO:0009289]				pilus [GO:0009289]		
d2co1a__d2ixqa1__1			Proteobacteria	Proteobacteria		pilus [GO:0009289]				pilus [GO:0009289]		
d2co4a__d2ixqb1__1			Proteobacteria	Proteobacteria		pilus [GO:0009289]				pilus [GO:0009289]		
d2coda1_d3syxa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	caveola [GO:0005901]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; phosphatase binding [GO:0019902]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; stem cell factor receptor binding [GO:0005173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inactivation of MAPK activity [GO:0000188]; MAPK cascade [GO:0000165]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of phosphatase activity [GO:0010923]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; regulation of MAPK cascade [GO:0043408]; regulation of protein deacetylation [GO:0090311]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]	regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	fibroblast growth factor receptor signaling pathway [GO:0008543]; inactivation of MAPK activity [GO:0000188]; MAPK cascade [GO:0000165]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of phosphatase activity [GO:0010923]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; regulation of MAPK cascade [GO:0043408]; regulation of protein deacetylation [GO:0090311]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]	cytosol [GO:0005829]	caveola [GO:0005901]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]	phosphatase binding [GO:0019902]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; stem cell factor receptor binding [GO:0005173]
d2coqa__d5d93b1__1	Metazoa	Metazoa	Chordata	Chordata		cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; FAD binding [GO:0071949]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]; extracellular matrix assembly [GO:0085029]; negative regulation of macroautophagy [GO:0016242]		cell redox homeostasis [GO:0045454]; extracellular matrix assembly [GO:0085029]; negative regulation of macroautophagy [GO:0016242]		cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]		FAD binding [GO:0071949]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide isomerase activity [GO:0003756]
d2coza1_d4b6ma___1	Metazoa		Chordata		cell projection [GO:0042995]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]; spindle [GO:0005819]; microtubule binding [GO:0008017]; microtubule anchoring [GO:0034453]		microtubule anchoring [GO:0034453]		cell projection [GO:0042995]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]; spindle [GO:0005819]		microtubule binding [GO:0008017]	
d2cpca1_d1jfqh2__1	Metazoa	Metazoa	Chordata	Chordata	3M complex [GO:1990393]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; M band [GO:0031430]; perinuclear region of cytoplasm [GO:0048471]; Z disc [GO:0030018]; cytoskeletal adaptor activity [GO:0008093]; cardiac myofibril assembly [GO:0055003]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of dendrite morphogenesis [GO:0050775]; post-translational protein modification [GO:0043687]; protein localization to Golgi apparatus [GO:0034067]; regulation of mitotic nuclear division [GO:0007088]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cardiac myofibril assembly [GO:0055003]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of dendrite morphogenesis [GO:0050775]; post-translational protein modification [GO:0043687]; protein localization to Golgi apparatus [GO:0034067]; regulation of mitotic nuclear division [GO:0007088]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	3M complex [GO:1990393]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; M band [GO:0031430]; perinuclear region of cytoplasm [GO:0048471]; Z disc [GO:0030018]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytoskeletal adaptor activity [GO:0008093]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2cpca1_d4ozgh1__1	Metazoa	Metazoa	Chordata	Chordata	3M complex [GO:1990393]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; M band [GO:0031430]; perinuclear region of cytoplasm [GO:0048471]; Z disc [GO:0030018]; cytoskeletal adaptor activity [GO:0008093]; cardiac myofibril assembly [GO:0055003]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of dendrite morphogenesis [GO:0050775]; post-translational protein modification [GO:0043687]; protein localization to Golgi apparatus [GO:0034067]; regulation of mitotic nuclear division [GO:0007088]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cardiac myofibril assembly [GO:0055003]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of dendrite morphogenesis [GO:0050775]; post-translational protein modification [GO:0043687]; protein localization to Golgi apparatus [GO:0034067]; regulation of mitotic nuclear division [GO:0007088]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	3M complex [GO:1990393]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; M band [GO:0031430]; perinuclear region of cytoplasm [GO:0048471]; Z disc [GO:0030018]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytoskeletal adaptor activity [GO:0008093]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2cpha1_d2dnga1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA binding [GO:0003723]; mRNA cis splicing, via spliceosome [GO:0045292]; multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]; translation initiation factor activity [GO:0003743]; developmental growth [GO:0048589]; sexual reproduction [GO:0019953]	mRNA cis splicing, via spliceosome [GO:0045292]; multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	developmental growth [GO:0048589]; sexual reproduction [GO:0019953]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]	RNA binding [GO:0003723]	translation initiation factor activity [GO:0003743]
d2cpja1_d4f25a1__1	Metazoa	Metazoa	Chordata	Chordata	fibrillar center [GO:0001650]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; RNA polymerase II transcription factor complex [GO:0090575]; chromatin binding [GO:0003682]; E-box binding [GO:0070888]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; activation of innate immune response [GO:0002218]; circadian rhythm [GO:0007623]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of circadian rhythm [GO:0042752]; RNA splicing [GO:0008380]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	activation of innate immune response [GO:0002218]; circadian rhythm [GO:0007623]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of circadian rhythm [GO:0042752]; RNA splicing [GO:0008380]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	fibrillar center [GO:0001650]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; RNA polymerase II transcription factor complex [GO:0090575]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	chromatin binding [GO:0003682]; E-box binding [GO:0070888]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]
d2cpna1_d2lbsb1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]; double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; pre-miRNA binding [GO:0070883]; pre-mRNA binding [GO:0036002]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; siRNA binding [GO:0035197]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA metabolic process [GO:0010586]; multicellular organism growth [GO:0035264]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of protein kinase activity [GO:0006469]; neural precursor cell proliferation [GO:0061351]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of translation [GO:0045727]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903798]; regulation of production of siRNA involved in RNA interference [GO:0090065]; regulation of viral transcription [GO:0046782]; single fertilization [GO:0007338]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; skeletal muscle tissue regeneration [GO:0043403]; spermatid development [GO:0007286]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; double-stranded RNA binding [GO:0003725]; ribonuclease III activity [GO:0004525]; box C/D snoRNA processing [GO:0034963]; box H/ACA snoRNA processing [GO:0034964]; chromatin organization [GO:0006325]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; pre-miRNA processing [GO:0031054]; primary miRNA processing [GO:0031053]; production of siRNA involved in RNA interference [GO:0030422]; regulation of fungal-type cell wall organization [GO:0060237]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; rRNA transcription [GO:0009303]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA metabolic process [GO:0010586]; multicellular organism growth [GO:0035264]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of protein kinase activity [GO:0006469]; neural precursor cell proliferation [GO:0061351]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of translation [GO:0045727]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903798]; regulation of production of siRNA involved in RNA interference [GO:0090065]; regulation of viral transcription [GO:0046782]; single fertilization [GO:0007338]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; skeletal muscle tissue regeneration [GO:0043403]; spermatid development [GO:0007286]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]	box C/D snoRNA processing [GO:0034963]; box H/ACA snoRNA processing [GO:0034964]; chromatin organization [GO:0006325]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; pre-miRNA processing [GO:0031054]; primary miRNA processing [GO:0031053]; production of siRNA involved in RNA interference [GO:0030422]; regulation of fungal-type cell wall organization [GO:0060237]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; rRNA transcription [GO:0009303]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; pre-miRNA binding [GO:0070883]; pre-mRNA binding [GO:0036002]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; siRNA binding [GO:0035197]	double-stranded RNA binding [GO:0003725]; ribonuclease III activity [GO:0004525]
d2cpra1_d2e1fa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; membrane [GO:0016020]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; 3'-5'-exoribonuclease activity [GO:0000175]; exoribonuclease activity [GO:0004532]; nucleotide binding [GO:0000166]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; telomerase RNA binding [GO:0070034]; CUT catabolic process [GO:0071034]; dosage compensation by inactivation of X chromosome [GO:0009048]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; histone mRNA catabolic process [GO:0071044]; maturation of 5.8S rRNA [GO:0000460]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent antisense transcript catabolic process [GO:0071040]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent snoRNA catabolic process [GO:0071036]; nuclear polyadenylation-dependent snRNA catabolic process [GO:0071037]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; regulation of telomerase RNA localization to Cajal body [GO:1904872]; rRNA processing [GO:0006364]	centrosome [GO:0005813]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; replication fork [GO:0005657]; 3'-5' DNA helicase activity [GO:0043138]; 3'-5' exonuclease activity [GO:0008408]; 3'-flap-structured DNA binding [GO:0070337]; 8-hydroxy-2'-deoxyguanosine DNA binding [GO:1905773]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; bubble DNA binding [GO:0000405]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; exonuclease activity [GO:0004527]; forked DNA-dependent helicase activity [GO:0061749]; four-way junction DNA binding [GO:0000400]; four-way junction helicase activity [GO:0009378]; G-quadruplex DNA binding [GO:0051880]; helicase activity [GO:0004386]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; MutLalpha complex binding [GO:0032405]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; telomeric D-loop binding [GO:0061821]; telomeric G-quadruplex DNA binding [GO:0061849]; Y-form DNA binding [GO:0000403]; aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of strand invasion [GO:0098530]; protein localization to nucleolus [GO:1902570]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; regulation of signal transduction by p53 class mediator [GO:1901796]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomeric D-loop disassembly [GO:0061820]	CUT catabolic process [GO:0071034]; dosage compensation by inactivation of X chromosome [GO:0009048]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; histone mRNA catabolic process [GO:0071044]; maturation of 5.8S rRNA [GO:0000460]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent antisense transcript catabolic process [GO:0071040]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent snoRNA catabolic process [GO:0071036]; nuclear polyadenylation-dependent snRNA catabolic process [GO:0071037]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; regulation of telomerase RNA localization to Cajal body [GO:1904872]; rRNA processing [GO:0006364]	aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of strand invasion [GO:0098530]; protein localization to nucleolus [GO:1902570]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; regulation of signal transduction by p53 class mediator [GO:1901796]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomeric D-loop disassembly [GO:0061820]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; membrane [GO:0016020]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	centrosome [GO:0005813]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; replication fork [GO:0005657]	3'-5'-exoribonuclease activity [GO:0000175]; exoribonuclease activity [GO:0004532]; nucleotide binding [GO:0000166]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; telomerase RNA binding [GO:0070034]	3'-5' DNA helicase activity [GO:0043138]; 3'-5' exonuclease activity [GO:0008408]; 3'-flap-structured DNA binding [GO:0070337]; 8-hydroxy-2'-deoxyguanosine DNA binding [GO:1905773]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; exonuclease activity [GO:0004527]; forked DNA-dependent helicase activity [GO:0061749]; four-way junction DNA binding [GO:0000400]; four-way junction helicase activity [GO:0009378]; G-quadruplex DNA binding [GO:0051880]; helicase activity [GO:0004386]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; MutLalpha complex binding [GO:0032405]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; telomeric D-loop binding [GO:0061821]; telomeric G-quadruplex DNA binding [GO:0061849]; Y-form DNA binding [GO:0000403]
d2cpta1_d2jq9a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; late endosome membrane [GO:0031902]; nucleus [GO:0005634]; spindle pole [GO:0000922]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cholesterol transport [GO:0030301]; endosomal transport [GO:0016197]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ESCRT III complex disassembly [GO:1904903]; late endosomal microautophagy [GO:0061738]; macroautophagy [GO:0016236]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; negative regulation of cell death [GO:0060548]; negative regulation of exosomal secretion [GO:1903542]; nucleus organization [GO:0006997]; positive regulation of centriole elongation [GO:1903724]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of viral life cycle [GO:1903902]; positive regulation of viral process [GO:0048524]; positive regulation of viral release from host cell [GO:1902188]; potassium ion transport [GO:0006813]; protein depolymerization [GO:0051261]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; regulation of viral process [GO:0050792]; response to lipid [GO:0033993]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; vacuole organization [GO:0007033]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosome [GO:0005764]; midbody [GO:0030496]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; spindle pole [GO:0000922]; vacuolar membrane [GO:0005774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; abscission [GO:0009838]; actomyosin contractile ring contraction [GO:0000916]; cell division [GO:0051301]; cytoskeleton-dependent cytokinesis [GO:0061640]; endosomal transport [GO:0016197]; endosomal vesicle fusion [GO:0034058]; ESCRT complex disassembly [GO:1904896]; ESCRT III complex disassembly [GO:1904903]; intracellular cholesterol transport [GO:0032367]; late endosomal microautophagy [GO:0061738]; macroautophagy [GO:0016236]; midbody abscission [GO:0061952]; mitotic cytokinesis checkpoint [GO:0044878]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; negative regulation of cytokinesis [GO:0032466]; nuclear envelope organization [GO:0006998]; nuclear envelope reassembly [GO:0031468]; nucleus organization [GO:0006997]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral life cycle [GO:1903902]; positive regulation of viral release from host cell [GO:1902188]; protein targeting to lysosome [GO:0006622]; regulation of protein localization [GO:0032880]; regulation of protein localization to plasma membrane [GO:1903076]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; vacuole organization [GO:0007033]; vesicle budding from membrane [GO:0006900]; vesicle uncoating [GO:0072319]; vesicle-mediated transport [GO:0016192]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]	cholesterol transport [GO:0030301]; endosomal transport [GO:0016197]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ESCRT III complex disassembly [GO:1904903]; late endosomal microautophagy [GO:0061738]; macroautophagy [GO:0016236]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; negative regulation of cell death [GO:0060548]; negative regulation of exosomal secretion [GO:1903542]; nucleus organization [GO:0006997]; positive regulation of centriole elongation [GO:1903724]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of viral life cycle [GO:1903902]; positive regulation of viral process [GO:0048524]; positive regulation of viral release from host cell [GO:1902188]; potassium ion transport [GO:0006813]; protein depolymerization [GO:0051261]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; regulation of viral process [GO:0050792]; response to lipid [GO:0033993]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; vacuole organization [GO:0007033]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]	abscission [GO:0009838]; actomyosin contractile ring contraction [GO:0000916]; cell division [GO:0051301]; cytoskeleton-dependent cytokinesis [GO:0061640]; endosomal transport [GO:0016197]; endosomal vesicle fusion [GO:0034058]; ESCRT complex disassembly [GO:1904896]; ESCRT III complex disassembly [GO:1904903]; intracellular cholesterol transport [GO:0032367]; late endosomal microautophagy [GO:0061738]; macroautophagy [GO:0016236]; midbody abscission [GO:0061952]; mitotic cytokinesis checkpoint [GO:0044878]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; negative regulation of cytokinesis [GO:0032466]; nuclear envelope organization [GO:0006998]; nuclear envelope reassembly [GO:0031468]; nucleus organization [GO:0006997]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral life cycle [GO:1903902]; positive regulation of viral release from host cell [GO:1902188]; protein targeting to lysosome [GO:0006622]; regulation of protein localization [GO:0032880]; regulation of protein localization to plasma membrane [GO:1903076]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; vacuole organization [GO:0007033]; vesicle budding from membrane [GO:0006900]; vesicle-mediated transport [GO:0016192]; vesicle uncoating [GO:0072319]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; late endosome membrane [GO:0031902]; nucleus [GO:0005634]; spindle pole [GO:0000922]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosome [GO:0005764]; midbody [GO:0030496]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; spindle pole [GO:0000922]; vacuolar membrane [GO:0005774]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]
d2cpua2_d1j01a___1	Metazoa		Chordata	Actinobacteria	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]
d2cpxa1_d2dita1__1	Metazoa	Metazoa	Chordata	Chordata	RNA binding [GO:0003723]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2 snRNP [GO:0005686]; U2-type spliceosomal complex [GO:0005684]; RNA binding [GO:0003723]; mRNA splicing, via spliceosome [GO:0000398]; regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of transcription by RNA polymerase II [GO:0006357]; viral genome replication [GO:0019079]		mRNA splicing, via spliceosome [GO:0000398]; regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of transcription by RNA polymerase II [GO:0006357]; viral genome replication [GO:0019079]		nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2 snRNP [GO:0005686]; U2-type spliceosomal complex [GO:0005684]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d2cpya1_d5oo6h___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; RNA binding [GO:0003723]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]		7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	nucleoplasm [GO:0005654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]	RNA binding [GO:0003723]	mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]
d2cq2a1_d2kxha2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; iron ion binding [GO:0005506]; tRNA (uracil) methyltransferase activity [GO:0016300]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; oxidation-reduction process [GO:0055114]; tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]	cell junction [GO:0030054]; nucleoplasm [GO:0005654]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]	cellular response to DNA damage stimulus [GO:0006974]; oxidation-reduction process [GO:0055114]; tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]	apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell junction [GO:0030054]; nucleoplasm [GO:0005654]	2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; iron ion binding [GO:0005506]; tRNA (uracil) methyltransferase activity [GO:0016300]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d2cq2a1_d3l3ca___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; iron ion binding [GO:0005506]; tRNA (uracil) methyltransferase activity [GO:0016300]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; oxidation-reduction process [GO:0055114]; tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cellular response to DNA damage stimulus [GO:0006974]; oxidation-reduction process [GO:0055114]; tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; iron ion binding [GO:0005506]; tRNA (uracil) methyltransferase activity [GO:0016300]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]
d2cq4a1_d2rnea1__1	Metazoa	Metazoa	Chordata	Chordata	membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA binding [GO:0003723]; mRNA processing [GO:0006397]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; apoptotic process [GO:0006915]; negative regulation of cytokine biosynthetic process [GO:0042036]; negative regulation of translation [GO:0017148]; positive regulation of epithelial cell apoptotic process [GO:1904037]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of mRNA splicing, via spliceosome [GO:0048024]	mRNA processing [GO:0006397]	apoptotic process [GO:0006915]; negative regulation of cytokine biosynthetic process [GO:0042036]; negative regulation of translation [GO:0017148]; positive regulation of epithelial cell apoptotic process [GO:1904037]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of mRNA splicing, via spliceosome [GO:0048024]	membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	RNA binding [GO:0003723]	mRNA 3'-UTR AU-rich region binding [GO:0035925]
d2cq9a1_d2vcxb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; dendrite [GO:0030425]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 2 iron, 2 sulfur cluster binding [GO:0051537]; arsenate reductase (glutaredoxin) activity [GO:0008794]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; metal ion binding [GO:0046872]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; aging [GO:0007568]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; cellular response to superoxide [GO:0071451]; DNA protection [GO:0042262]; glutathione metabolic process [GO:0006749]; regulation of signal transduction [GO:0009966]; regulation of transcription, DNA-templated [GO:0006355]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to redox state [GO:0051775]; response to temperature stimulus [GO:0009266]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	aging [GO:0007568]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; cellular response to superoxide [GO:0071451]; DNA protection [GO:0042262]; glutathione metabolic process [GO:0006749]; regulation of signal transduction [GO:0009966]; regulation of transcription, DNA-templated [GO:0006355]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to redox state [GO:0051775]; response to temperature stimulus [GO:0009266]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; dendrite [GO:0030425]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	2 iron, 2 sulfur cluster binding [GO:0051537]; arsenate reductase (glutaredoxin) activity [GO:0008794]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; metal ion binding [GO:0046872]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d2cqca1_d5iqqd___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; cellular response to glucose stimulus [GO:0071333]; cerebral cortex regionalization [GO:0021796]; embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; protein complex oligomerization [GO:0051259]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; RNA splicing, via transesterification reactions [GO:0000375]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 14-3-3 protein binding [GO:0071889]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]; meiotic cell cycle [GO:0051321]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; snRNA catabolic process [GO:0016076]	cellular response to glucose stimulus [GO:0071333]; cerebral cortex regionalization [GO:0021796]; embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; protein complex oligomerization [GO:0051259]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; RNA splicing, via transesterification reactions [GO:0000375]	meiotic cell cycle [GO:0051321]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; snRNA catabolic process [GO:0016076]	cell [GO:0005623]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]	14-3-3 protein binding [GO:0071889]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]
d2cqha1_d1koha2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleus [GO:0005634]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; translation regulator activity [GO:0045182]; anatomical structure morphogenesis [GO:0009653]; mRNA transport [GO:0051028]; negative regulation of translation [GO:0017148]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of mRNA stability [GO:0043488]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	anatomical structure morphogenesis [GO:0009653]; mRNA transport [GO:0051028]; negative regulation of translation [GO:0017148]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of mRNA stability [GO:0043488]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; translation regulator activity [GO:0045182]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d2cqpa1_d2ghpd2__1	Metazoa	Fungi	Chordata	Ascomycota	nucleoplasm [GO:0005654]; RNA binding [GO:0003723]	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]		spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	nucleoplasm [GO:0005654]	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]	RNA binding [GO:0003723]	RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]
d2cqva1_d2ifga2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; actin binding [GO:0003779]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; myosin light chain kinase activity [GO:0004687]; protein kinase activity [GO:0004672]; aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cardiovascular system development [GO:0072358]; cellular hypotonic response [GO:0071476]; muscle contraction [GO:0006936]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cardiovascular system development [GO:0072358]; cellular hypotonic response [GO:0071476]; muscle contraction [GO:0006936]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin cytoskeleton [GO:0015629]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]	actin binding [GO:0003779]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; myosin light chain kinase activity [GO:0004687]; protein kinase activity [GO:0004672]	cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]
d2cqva1_d4rqqa1__1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; actin binding [GO:0003779]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; myosin light chain kinase activity [GO:0004687]; protein kinase activity [GO:0004672]; aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cardiovascular system development [GO:0072358]; cellular hypotonic response [GO:0071476]; muscle contraction [GO:0006936]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]		aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cardiovascular system development [GO:0072358]; cellular hypotonic response [GO:0071476]; muscle contraction [GO:0006936]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]		actin cytoskeleton [GO:0015629]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]		actin binding [GO:0003779]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; myosin light chain kinase activity [GO:0004687]; protein kinase activity [GO:0004672]	
d2cqza__d2ovva___1		Metazoa	Euryarchaeota	Chordata	5'-deoxynucleotidase activity [GO:0002953]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]		cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]	5'-deoxynucleotidase activity [GO:0002953]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]
d2cqze__d1mkdi___1		Metazoa	Euryarchaeota	Chordata	5'-deoxynucleotidase activity [GO:0002953]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]		adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]		apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	5'-deoxynucleotidase activity [GO:0002953]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d2cr2a1_d4gjhc___1	Metazoa	Metazoa	Chordata	Chordata	Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor binding [GO:0001085]; ubiquitin protein ligase binding [GO:0031625]; glucose homeostasis [GO:0042593]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of proteolysis [GO:0030162]; ubiquitin-dependent protein catabolic process [GO:0006511]	CD40 receptor complex [GO:0035631]; centrosome [GO:0005813]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]	glucose homeostasis [GO:0042593]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of proteolysis [GO:0030162]; ubiquitin-dependent protein catabolic process [GO:0006511]	apoptotic process [GO:0006915]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]	Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	CD40 receptor complex [GO:0035631]; centrosome [GO:0005813]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	RNA polymerase II transcription factor binding [GO:0001085]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; thioesterase binding [GO:0031996]; tumor necrosis factor receptor binding [GO:0005164]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d2cr6a1_d1s7xj1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2cr7a1_d1e91a___1	Metazoa	Metazoa	Chordata	Chordata	autosome [GO:0030849]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; Sin3 complex [GO:0016580]; X chromosome [GO:0000805]; XY body [GO:0001741]; Y chromosome [GO:0000806]; chromatin binding [GO:0003682]; transcription corepressor activity [GO:0003714]; cardiac muscle tissue development [GO:0048738]; histone deacetylation [GO:0016575]; negative regulation of cell cycle [GO:0045786]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; skeletal muscle tissue development [GO:0007519]	autosome [GO:0030849]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; Sin3 complex [GO:0016580]; X chromosome [GO:0000805]; XY body [GO:0001741]; Y chromosome [GO:0000806]; chromatin binding [GO:0003682]; transcription corepressor activity [GO:0003714]; cardiac muscle tissue development [GO:0048738]; histone deacetylation [GO:0016575]; negative regulation of cell cycle [GO:0045786]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; skeletal muscle tissue development [GO:0007519]	cardiac muscle tissue development [GO:0048738]; histone deacetylation [GO:0016575]; negative regulation of cell cycle [GO:0045786]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; skeletal muscle tissue development [GO:0007519]	cardiac muscle tissue development [GO:0048738]; histone deacetylation [GO:0016575]; negative regulation of cell cycle [GO:0045786]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; skeletal muscle tissue development [GO:0007519]	autosome [GO:0030849]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; Sin3 complex [GO:0016580]; X chromosome [GO:0000805]; XY body [GO:0001741]; Y chromosome [GO:0000806]	autosome [GO:0030849]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; Sin3 complex [GO:0016580]; X chromosome [GO:0000805]; XY body [GO:0001741]; Y chromosome [GO:0000806]	chromatin binding [GO:0003682]; transcription corepressor activity [GO:0003714]	chromatin binding [GO:0003682]; transcription corepressor activity [GO:0003714]
d2crka1_d4am1a1__1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]	arginine binding [GO:0034618]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; dTDP metabolic process [GO:0046072]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]	dTDP metabolic process [GO:0046072]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	extracellular space [GO:0005615]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	arginine binding [GO:0034618]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d2crma1_d2vkxd2__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; vesicle membrane [GO:0012506]; RNA binding [GO:0003723]; cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; virus receptor activity [GO:0001618]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; commissural neuron axon guidance [GO:0071679]; interferon-gamma-mediated signaling pathway [GO:0060333]; MAPK cascade [GO:0000165]; regulation of semaphorin-plexin signaling pathway [GO:2001260]	cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286]	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; commissural neuron axon guidance [GO:0071679]; interferon-gamma-mediated signaling pathway [GO:0060333]; MAPK cascade [GO:0000165]; regulation of semaphorin-plexin signaling pathway [GO:2001260]	acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; vesicle membrane [GO:0012506]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	RNA binding [GO:0003723]	identical protein binding [GO:0042802]; virus receptor activity [GO:0001618]
d2crpa1_d1ym7b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]; alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]; cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein phosphorylation [GO:0006468]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein phosphorylation [GO:0006468]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]
d2crpa1_d2d9ja1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; G-protein beta-subunit binding [GO:0031681]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; protein folding [GO:0006457]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; protein folding [GO:0006457]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	G-protein beta-subunit binding [GO:0031681]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]
d2crya1_d4lhug1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; glomerulus morphogenesis [GO:0072102]; hemopoiesis [GO:0030097]; hippocampus development [GO:0021766]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inter-male aggressive behavior [GO:0002121]; neuron migration [GO:0001764]; neuron projection morphogenesis [GO:0048812]; principal sensory nucleus of trigeminal nerve development [GO:0021740]; synapse assembly [GO:0007416]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	glomerulus morphogenesis [GO:0072102]; hemopoiesis [GO:0030097]; hippocampus development [GO:0021766]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inter-male aggressive behavior [GO:0002121]; neuron migration [GO:0001764]; neuron projection morphogenesis [GO:0048812]; principal sensory nucleus of trigeminal nerve development [GO:0021740]; synapse assembly [GO:0007416]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	axon [GO:0030424]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2cspa1_d3b83c1__1	Metazoa		Chordata		cell junction [GO:0030054]; plasma membrane [GO:0005886]; synapse [GO:0045202]; negative regulation of phosphatase activity [GO:0010923]; neuromuscular synaptic transmission [GO:0007274]		negative regulation of phosphatase activity [GO:0010923]; neuromuscular synaptic transmission [GO:0007274]		cell junction [GO:0030054]; plasma membrane [GO:0005886]; synapse [GO:0045202]			
d2cssa1_d2dmza1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cell projection [GO:0042995]; cytoskeleton of presynaptic active zone [GO:0048788]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; presynaptic active zone cytoplasmic component [GO:0098831]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; GTPase regulator activity [GO:0030695]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; acrosomal vesicle exocytosis [GO:0060478]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; glutamate secretion [GO:0014047]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; protein-containing complex assembly [GO:0065003]; regulated exocytosis [GO:0045055]; regulation of membrane potential [GO:0042391]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to stimulus [GO:0050896]; secretion [GO:0046903]; synaptic vesicle exocytosis [GO:0016079]; visual perception [GO:0007601]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	acrosomal vesicle exocytosis [GO:0060478]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; glutamate secretion [GO:0014047]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; protein-containing complex assembly [GO:0065003]; regulated exocytosis [GO:0045055]; regulation of membrane potential [GO:0042391]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to stimulus [GO:0050896]; secretion [GO:0046903]; synaptic vesicle exocytosis [GO:0016079]; visual perception [GO:0007601]	bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	cell junction [GO:0030054]; cell projection [GO:0042995]; cytoskeleton of presynaptic active zone [GO:0048788]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; presynaptic active zone [GO:0048786]; presynaptic active zone cytoplasmic component [GO:0098831]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	GTPase regulator activity [GO:0030695]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]	
d2csxb2_d4dlpa2__1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]
d2ct6a1_d1j08g1__1	Metazoa		Chordata	Euryarchaeota	nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; SH3 domain binding [GO:0017124]	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]	nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]	cell [GO:0005623]	SH3 domain binding [GO:0017124]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d2ct8a2_d2x1lc1__1			Aquificae	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]
d2ct8b2_d1f4la1__1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2ct8b2_d4mw4b2__1			Aquificae		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]
d2ctba__d2pj7b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2ctca__d4gm5a___1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	proteolysis [GO:0006508]		extracellular space [GO:0005615]		metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2ctfa1_d3vkec1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]	cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; cadherin binding [GO:0045296]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; sequence-specific single stranded DNA binding [GO:0098847]; single-stranded DNA binding [GO:0003697]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA metabolic process [GO:0016070]; viral RNA genome replication [GO:0039694]	cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]	mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; RNA metabolic process [GO:0016070]; viral RNA genome replication [GO:0039694]	cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]	cadherin binding [GO:0045296]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; sequence-specific single stranded DNA binding [GO:0098847]; single-stranded DNA binding [GO:0003697]
d2ctha__d1newa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	anaerobic respiration [GO:0009061]	anaerobic respiration [GO:0009061]	periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2ctma1_d3aevb1__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]	RNA binding [GO:0003723]	cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]		cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d2ctna__d1odba1__1	Metazoa	Metazoa	Chordata	Chordata	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	troponin complex [GO:0005861]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d2ctsa__d1owcb___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]; carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; citrate (Si)-synthase activity [GO:0004108]; identical protein binding [GO:0042802]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]	cytosol [GO:0005829]	citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]	citrate (Si)-synthase activity [GO:0004108]; identical protein binding [GO:0042802]
d2cu2a2_d3t7mb1__1		Metazoa	Deinococcus-Thermus	Chordata	isomerase activity [GO:0016853]; nucleotidyltransferase activity [GO:0016779]; biosynthetic process [GO:0009058]	cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]; glycogenin glucosyltransferase activity [GO:0008466]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity [GO:0102751]; glycogen biosynthetic process [GO:0005978]; neutrophil degranulation [GO:0043312]	biosynthetic process [GO:0009058]	glycogen biosynthetic process [GO:0005978]; neutrophil degranulation [GO:0043312]		cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]	isomerase activity [GO:0016853]; nucleotidyltransferase activity [GO:0016779]	glycogenin glucosyltransferase activity [GO:0008466]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity [GO:0102751]
d2cu5a__d1vmfc1__1			Deinococcus-Thermus	Firmicutes								
d2cu5a__d2p6ha___1			Deinococcus-Thermus	Crenarchaeota								
d2cu5c__d1vphe1__1			Deinococcus-Thermus	Crenarchaeota								
d2cuia1_d2ed7a1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; collagen fibril binding [GO:0098633]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]	axon [GO:0030424]; cytosol [GO:0005829]; integral component of postsynaptic density membrane [GO:0099061]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; netrin receptor activity [GO:0005042]; transmembrane signaling receptor activity [GO:0004888]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dorsal/ventral axon guidance [GO:0033563]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of netrin-activated signaling pathway [GO:1902842]; negative regulation of neuron projection development [GO:0010977]; neuron migration [GO:0001764]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of neuron death [GO:1901214]; spinal cord ventral commissure morphogenesis [GO:0021965]	actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]	anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dorsal/ventral axon guidance [GO:0033563]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of netrin-activated signaling pathway [GO:1902842]; negative regulation of neuron projection development [GO:0010977]; neuron migration [GO:0001764]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of neuron death [GO:1901214]; spinal cord ventral commissure morphogenesis [GO:0021965]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	axon [GO:0030424]; cytosol [GO:0005829]; integral component of postsynaptic density membrane [GO:0099061]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	collagen fibril binding [GO:0098633]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; integrin binding [GO:0005178]	netrin receptor activity [GO:0005042]; transmembrane signaling receptor activity [GO:0004888]
d2cuja1_d3zn0a1__1	Metazoa	Metazoa	Chordata	Chordata	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; chromosome [GO:0005694]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; SAGA-type complex [GO:0070461]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; mitotic cell cycle [GO:0000278]; positive regulation of histone acetylation [GO:0035066]; regulation of histone deacetylation [GO:0031063]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; mitotic cell cycle [GO:0000278]; positive regulation of histone acetylation [GO:0035066]; regulation of histone deacetylation [GO:0031063]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; chromosome [GO:0005694]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; SAGA-type complex [GO:0070461]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2cuma1_d3s9dd1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; collagen fibril binding [GO:0098633]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	collagen fibril binding [GO:0098633]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; integrin binding [GO:0005178]	cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]
d2cuta__d3dd5a___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cutinase activity [GO:0050525]	cutinase activity [GO:0050525]
d2cuua__d4dygb___1		Viridiplantae		Streptophyta	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]; polysaccharide catabolic process [GO:0000272]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]; polysaccharide catabolic process [GO:0000272]	host cell cytoplasm [GO:0030430]	extracellular region [GO:0005576]	lysozyme activity [GO:0003796]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d2cuza2_d1maua___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	glutamyl-tRNA aminoacylation [GO:0006424]	tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d2cv0a1_d5h4vd2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	glutamyl-tRNA aminoacylation [GO:0006424]	glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2cv0b2_d5o0db___1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	glutamyl-tRNA aminoacylation [GO:0006424]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d2cv2b1_d2cfob2__1			Deinococcus-Thermus	Cyanobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	glutamyl-tRNA aminoacylation [GO:0006424]	glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2cv2b2_d1qtqa2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	glutamyl-tRNA aminoacylation [GO:0006424]	glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]
d2cv3a__d4x6ma___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d2cv5f__d1p3ka___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2cv5g__d5bnxa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2cvda1_d4iq1b2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	
d2cvdc1_d5ddlb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2cvdc2_d4iq1a1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	
d2cvdd2_d1syra___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytosol [GO:0005829]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	protein disulfide oxidoreductase activity [GO:0015035]
d2cvea2_d1u2ra4__1		Fungi	Deinococcus-Thermus	Ascomycota		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]
d2cvea2_d1vi7a2__1			Deinococcus-Thermus	Proteobacteria								
d2cvob2_d4r3nb2__1	Viridiplantae		Streptophyta	Firmicutes	chloroplast [GO:0009507]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	arginine biosynthetic process [GO:0006526]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	chloroplast [GO:0009507]		N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]
d2cvpa__d3ooje2__1	Metazoa		Chordata	Proteobacteria	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]
d2cvpb__d4u6na1__1	Metazoa		Chordata	Proteobacteria	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate derivative binding [GO:0097367]; identical protein binding [GO:0042802]; carbohydrate derivative metabolic process [GO:1901135]; DNA replication [GO:0006260]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate derivative metabolic process [GO:1901135]; DNA replication [GO:0006260]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate derivative binding [GO:0097367]; identical protein binding [GO:0042802]
d2cvqb1_d5pgue___1		Metazoa	Deinococcus-Thermus	Chordata	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	L-malate dehydrogenase activity [GO:0030060]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d2cvqb2_d3vpfd2__1			Deinococcus-Thermus		L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]				L-malate dehydrogenase activity [GO:0030060]	
d2cvqb2_d3wswb2__1			Deinococcus-Thermus	Firmicutes	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d2cw0a2_d2nvyc2__1		Fungi	Deinococcus-Thermus	Ascomycota	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	transcription, DNA-templated [GO:0006351]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]		cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]
d2cw0f3_d4g7op1__1			Deinococcus-Thermus	Deinococcus-Thermus	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]			DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d2cw0l2_d1twcc2__1		Fungi	Deinococcus-Thermus	Ascomycota	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	transcription, DNA-templated [GO:0006351]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]		cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]
d2cw2a1_d4guno1__1		Fungi	Perkinsozoa	Ascomycota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2cw2a2_d4gunc2__1		Fungi	Perkinsozoa	Ascomycota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2cw2b2_d1idsc2__1			Perkinsozoa	Actinobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2cw3a1_d4gund1__1		Fungi	Perkinsozoa	Ascomycota	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			integral component of membrane [GO:0016021]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2cwdc__d2p4ud___1		Metazoa	Deinococcus-Thermus	Chordata	protein tyrosine phosphatase activity [GO:0004725]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; sarcolemma [GO:0042383]; acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]				cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; sarcolemma [GO:0042383]	protein tyrosine phosphatase activity [GO:0004725]	acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]
d2cwdd__d1phra___1		Metazoa	Deinococcus-Thermus	Chordata	protein tyrosine phosphatase activity [GO:0004725]	cytoplasm [GO:0005737]; acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]				cytoplasm [GO:0005737]	protein tyrosine phosphatase activity [GO:0004725]	acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]
d2cwhb__d1z2ib___1			Proteobacteria	Proteobacteria	delta1-piperideine-2-carboxylate reductase activity [GO:0047125]; N-methylalanine dehydrogenase activity [GO:0050132]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]					delta1-piperideine-2-carboxylate reductase activity [GO:0047125]; N-methylalanine dehydrogenase activity [GO:0050132]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2cwia__d4iata___1	Metazoa	Metazoa	Chordata	Chordata	lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]; cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2cwib__d3c8sa___1	Metazoa		Chordata		lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]; cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]	lysozyme activity [GO:0003796]
d2cwkb__d3ztqe___1			Euryarchaeota	Aquificae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2cwlb__d3pvtc1__1			Deinococcus-Thermus	Proteobacteria		cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]		phenylacetate catabolic process [GO:0010124]		cytosol [GO:0005829]		
d2cwma__d2eigd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2cwmd__d4lbqc___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; galactose binding [GO:0005534]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of viral entry into host cell [GO:0046598]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of viral entry into host cell [GO:0046598]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; galactose binding [GO:0005534]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]
d2cwna1_d1fq0a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; carbohydrate binding [GO:0030246]; monosaccharide binding [GO:0048029]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glyceraldehyde-3-phosphate metabolic process [GO:0019682]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glyceraldehyde-3-phosphate metabolic process [GO:0019682]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	metabolic process [GO:0008152]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; membrane [GO:0016020]	carbohydrate binding [GO:0030246]; monosaccharide binding [GO:0048029]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]
d2cwsa1_d1q2ea___1		Fungi	Proteobacteria	Ascomycota	lyase activity [GO:0016829]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	lyase activity [GO:0016829]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d2cwwb1_d2ey4a1__1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; methyltransferase activity [GO:0008168]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	snoRNA binding [GO:0030515]; pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	rRNA processing [GO:0006364]	pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	cytoplasm [GO:0005737]		methyltransferase activity [GO:0008168]; RNA binding [GO:0003723]	snoRNA binding [GO:0030515]
d2cx5b__d3rijd___1			Deinococcus-Thermus	Deinococcus-Thermus	aminoacyl-tRNA editing activity [GO:0002161]; translation [GO:0006412]	aminoacyl-tRNA editing activity [GO:0002161]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]			aminoacyl-tRNA editing activity [GO:0002161]	aminoacyl-tRNA editing activity [GO:0002161]
d2cx9c1_d2ebaa2__1			Deinococcus-Thermus	Deinococcus-Thermus	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]					acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d2cx9d1_d4m9aa2__1			Deinococcus-Thermus	Proteobacteria	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]					acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d2cxba__d3h1jq1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	photosynthesis [GO:0015979]		periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d2cxbb__d5klvd1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	photosynthesis [GO:0015979]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	periplasmic space [GO:0042597]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d2cxga2_d5ghla___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]; polysaccharide metabolic process [GO:0005976]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]; polysaccharide metabolic process [GO:0005976]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]
d2cxga3_d3hg4a2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d2cxna__d2o2da___1	Metazoa		Chordata		ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	glycosome [GO:0020015]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	glycosome [GO:0020015]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	glucose-6-phosphate isomerase activity [GO:0004347]
d2cxoa__d1hm5a___1	Metazoa	Metazoa	Chordata	Chordata	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]
d2cxoa__d1x9ha___1	Metazoa		Chordata	Crenarchaeota	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]; carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]
d2cxpa__d1x92b1__1	Metazoa		Chordata	Proteobacteria	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]; lipopolysaccharide core region biosynthetic process [GO:0009244]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]; lipopolysaccharide core region biosynthetic process [GO:0009244]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]
d2cxqa__d4wmjd___1	Metazoa	Metazoa	Chordata	Arthropoda	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	glucose-6-phosphate isomerase activity [GO:0004347]
d2cxra__d1xtba___1	Metazoa	Metazoa	Chordata	Chordata	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]
d2cxta__d2yvab___1	Metazoa		Chordata	Proteobacteria	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate derivative binding [GO:0097367]; identical protein binding [GO:0042802]; carbohydrate derivative metabolic process [GO:1901135]; DNA replication [GO:0006260]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate derivative metabolic process [GO:1901135]; DNA replication [GO:0006260]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate derivative binding [GO:0097367]; identical protein binding [GO:0042802]
d2cxtb__d2decb___1	Metazoa		Chordata	Euryarchaeota	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate derivative binding [GO:0097367]; carbohydrate derivative metabolic process [GO:1901135]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate derivative metabolic process [GO:1901135]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate derivative binding [GO:0097367]
d2cxtb__d4wmjb___1	Metazoa	Metazoa	Chordata	Arthropoda	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	glucose-6-phosphate isomerase activity [GO:0004347]
d2cxua__d2o2cc___1	Metazoa		Chordata		ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	glycosome [GO:0020015]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	glycosome [GO:0020015]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	glucose-6-phosphate isomerase activity [GO:0004347]
d2cxub__d1jiqb___1	Metazoa	Metazoa	Chordata	Chordata	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d2cxva__d1qgfa___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular space [GO:0005615]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2cy3a__d3caoa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	anaerobic respiration [GO:0009061]	anaerobic respiration [GO:0009061]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2cy6d__d1v6jd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2cyba__d1g59c2__1			Euryarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	tyrosyl-tRNA aminoacylation [GO:0006437]	glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2cyga1_d1jz8b5__1	Viridiplantae		Streptophyta	Proteobacteria	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2cyka__d1ykba___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]; activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]; acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	activation of Janus kinase activity [GO:0042976]; B cell differentiation [GO:0030183]; cholesterol metabolic process [GO:0008203]; connective tissue growth factor biosynthetic process [GO:0045189]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; immune response [GO:0006955]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuroinflammatory response [GO:0150079]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular respiration [GO:1901857]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of immune response [GO:0050776]; regulation of isotype switching [GO:0045191]; regulation of phosphorylation [GO:0042325]; T cell activation [GO:0042110]; T-helper 2 cell cytokine production [GO:0035745]; type 2 immune response [GO:0042092]	acute-phase response [GO:0006953]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; response to glucocorticoid [GO:0051384]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-4 receptor binding [GO:0005136]	cytokine activity [GO:0005125]; interleukin-22 receptor binding [GO:0045518]
d2cyzb__d4zgeh___1			Actinobacteria	Proteobacteria	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d2cz0b__d3qxef___1			Actinobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	
d2cz0b__d3wvdb___1			Actinobacteria	Actinobacteria	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d2cz5b__d1dqxa___1		Fungi	Euryarchaeota	Ascomycota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]		cytosol [GO:0005829]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2cz6b__d3x28b___1			Actinobacteria	Actinobacteria	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d2cz8a1_d3oqte___1			Deinococcus-Thermus	Actinobacteria	nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2cz8h__d2vxaf___1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2cz9a1_d2pnzb1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; galactokinase activity [GO:0004335]; galactose binding [GO:0005534]; magnesium ion binding [GO:0000287]; galactose metabolic process [GO:0006012]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	galactose metabolic process [GO:0006012]	RNA catabolic process [GO:0006401]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	ATP binding [GO:0005524]; galactokinase activity [GO:0004335]; galactose binding [GO:0005534]; magnesium ion binding [GO:0000287]	3'-5'-exoribonuclease activity [GO:0000175]
d2czca1_d1dc5a2__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; membrane [GO:0016020]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2czcc2_d1cf2o2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2czcc2_d1yl7d2__1			Euryarchaeota	Actinobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]
d2czda__d4fiqe___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; pyridoxal phosphate biosynthetic process [GO:0042823]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal phosphate biosynthetic process [GO:0042823]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d2czea__d2issc___1			Euryarchaeota	Thermotogae	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d2czea__d3exsd___1			Euryarchaeota	Firmicutes	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2czeb__d1k3ua___1			Euryarchaeota	Proteobacteria	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]
d2czub__d2ftba___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; response to glucocorticoid [GO:0051384]	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; response to glucocorticoid [GO:0051384]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	cytoplasm [GO:0005737]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]	lipid binding [GO:0008289]
d2d01a__d2vv8c___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]		integral component of plasma membrane [GO:0005887]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d2d03l1_d2ny3d1__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d2d04b__d1bwup___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d2d04c__d3r0ea___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d2d04f__d1xd6a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d2d04f__d5t1xa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d2d04h__d5t1xd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d2d05a__d4ilya___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; chitosanase activity [GO:0016977]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; chitosanase activity [GO:0016977]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	chitosanase activity [GO:0016977]	chitosanase activity [GO:0016977]
d2d05a__d5kxza___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; chitosanase activity [GO:0016977]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	carbohydrate metabolic process [GO:0005975]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	chitosanase activity [GO:0016977]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2d0ea1_d2h7qa___1			Actinobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2d0kb__d3eemb1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d2d0pa1_d1nbwc1__1			Proteobacteria	Proteobacteria		ATP binding [GO:0005524]; glycerol dehydratase activity [GO:0046405]; metal ion binding [GO:0046872]						ATP binding [GO:0005524]; glycerol dehydratase activity [GO:0046405]; metal ion binding [GO:0046872]
d2d0pd__d1mmfb___1			Proteobacteria	Proteobacteria		cobalamin binding [GO:0031419]; glycerol dehydratase activity [GO:0046405]						cobalamin binding [GO:0031419]; glycerol dehydratase activity [GO:0046405]
d2d0sa__d5cibb___1		Fungi	Proteobacteria	Ascomycota	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2d0vi__d4tqoc___1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; calcium ion binding [GO:0005509]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; alcohol dehydrogenase (acceptor) activity [GO:0018468]; calcium ion binding [GO:0005509]; methanol oxidation [GO:0015946]; oxidation-reduction process [GO:0055114]		methanol oxidation [GO:0015946]; oxidation-reduction process [GO:0055114]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	calcium ion binding [GO:0005509]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]	alcohol dehydrogenase (acceptor) activity [GO:0018468]; calcium ion binding [GO:0005509]
d2d0vj__d1h4jf___1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; calcium ion binding [GO:0005509]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]; methanol metabolic process [GO:0015945]		methanol metabolic process [GO:0015945]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; oxidoreductase activity, acting on CH-OH group of donors [GO:0016614]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]
d2d0wa__d1jdla___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methanol metabolic process [GO:0015945]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]	methanol metabolic process [GO:0015945]	photosynthesis [GO:0015979]	periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2d10a1_d1mk9h1__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]
d2d10a1_d4zria2__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]
d2d11c3_d2aeha3__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]; protein-containing complex assembly [GO:0065003]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]; actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	protein-containing complex assembly [GO:0065003]	actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	apical plasma membrane [GO:0016324]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]	beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]	ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]
d2d12a__d4za3b2__1		Viridiplantae		Streptophyta		rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]				rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2d12b__d3rtjb2__1		Viridiplantae		Streptophyta		endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2d16d__d2ekma___1			Euryarchaeota	Crenarchaeota								
d2d1kb__d1dewb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]; apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]
d2d1kb__d4jg3a1__1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]; apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]	exodeoxyribonuclease III activity [GO:0008853]; DNA repair [GO:0006281]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of single-species biofilm formation [GO:1900190]	apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]	DNA repair [GO:0006281]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of single-species biofilm formation [GO:1900190]	extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]		actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]	exodeoxyribonuclease III activity [GO:0008853]
d2d1oa__d3b8za___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]
d2d1pc1_d2d1pg2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]; sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]; tRNA wobble position uridine thiolation [GO:0002143]	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]; sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]	sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]	sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]
d2d1ph__d2hy5c1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]; sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]; tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]	cytoplasm [GO:0005737]	sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]	
d2d20a1_d2pwfa1__1			Actinobacteria	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d2d20b2_d4zgrb1__1		Viridiplantae	Actinobacteria	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	polysaccharide catabolic process [GO:0000272]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			endo-1,4-beta-xylanase activity [GO:0031176]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2d21a__d4jdfa___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	outer membrane-bounded periplasmic space [GO:0030288]; putrescine binding [GO:0019810]; putrescine transport [GO:0015847]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	putrescine transport [GO:0015847]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	putrescine binding [GO:0019810]
d2d22a1_d3vd5b3__1			Actinobacteria	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	endo-1,4-beta-xylanase activity [GO:0031176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2d22a2_d5bp5b2__1			Actinobacteria	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]				endo-1,4-beta-xylanase activity [GO:0031176]	
d2d23a1_d1ghol5__1			Actinobacteria		endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]				endo-1,4-beta-xylanase activity [GO:0031176]	
d2d24a1_d2x8rf___1		Fungi	Actinobacteria	Ascomycota	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	polysaccharide catabolic process [GO:0000272]	cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]			endo-1,4-beta-xylanase activity [GO:0031176]	lysozyme activity [GO:0003796]
d2d29b1_d2rehd1__1		Fungi	Deinococcus-Thermus	Ascomycota	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]		nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]			acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d2d29b1_d4n5fb2__1			Deinococcus-Thermus	Proteobacteria	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]					acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d2d2cd1_d1sqxe2__1		Metazoa	Cyanobacteria	Chordata	cytochrome b6f complex [GO:0009512]; integral component of membrane [GO:0016021]; thylakoid membrane [GO:0042651]; electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity [GO:0045158]; cytochrome complex assembly [GO:0017004]; photosynthesis [GO:0015979]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytochrome complex assembly [GO:0017004]; photosynthesis [GO:0015979]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytochrome b6f complex [GO:0009512]; integral component of membrane [GO:0016021]; thylakoid membrane [GO:0042651]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity [GO:0045158]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d2d2ma__d1yhua___1	Metazoa	Metazoa	Annelida	Annelida	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2d2mc__d3wcta___1	Metazoa	Metazoa	Annelida	Annelida	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2d2oa3_d1bg9a2__1		Viridiplantae	Firmicutes	Streptophyta	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d2d2oa3_d4ttga3__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2d2ob1_d2oxha___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	
d2d2va__d4kx5a___1		Metazoa	Cyanobacteria	Chordata	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]; sucrose biosynthetic process [GO:0005986]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; transferase activity [GO:0016740]; adenosine metabolic process [GO:0046085]; defense response to virus [GO:0051607]; nucleotide metabolic process [GO:0009117]	sucrose biosynthetic process [GO:0005986]	adenosine metabolic process [GO:0046085]; defense response to virus [GO:0051607]; nucleotide metabolic process [GO:0009117]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]	5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; transferase activity [GO:0016740]
d2d2zb1_d4zb9d1__1	Metazoa	Fungi	Chordata	Basidiomycota	actin cytoskeleton [GO:0015629]; apical part of cell [GO:0045177]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; centrosome [GO:0005813]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; microvillus [GO:0005902]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; chloride transport [GO:0006821]; endothelial cell morphogenesis [GO:0001886]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; fertilization [GO:0009566]; keratinocyte differentiation [GO:0030216]; multicellular organism growth [GO:0035264]; negative regulation of cell migration [GO:0030336]; regulation of cytoskeleton organization [GO:0051493]; regulation of ion transmembrane transport [GO:0034765]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; vacuolar acidification [GO:0007035]		angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; chloride transport [GO:0006821]; endothelial cell morphogenesis [GO:0001886]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; fertilization [GO:0009566]; keratinocyte differentiation [GO:0030216]; multicellular organism growth [GO:0035264]; negative regulation of cell migration [GO:0030336]; regulation of cytoskeleton organization [GO:0051493]; regulation of ion transmembrane transport [GO:0034765]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; vacuolar acidification [GO:0007035]		actin cytoskeleton [GO:0015629]; apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; centrosome [GO:0005813]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; microvillus [GO:0005902]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]		chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	
d2d2zc1_d2r6kb2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical part of cell [GO:0045177]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; centrosome [GO:0005813]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; microvillus [GO:0005902]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; chloride transport [GO:0006821]; endothelial cell morphogenesis [GO:0001886]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; fertilization [GO:0009566]; keratinocyte differentiation [GO:0030216]; multicellular organism growth [GO:0035264]; negative regulation of cell migration [GO:0030336]; regulation of cytoskeleton organization [GO:0051493]; regulation of ion transmembrane transport [GO:0034765]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; vacuolar acidification [GO:0007035]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; chloride transport [GO:0006821]; endothelial cell morphogenesis [GO:0001886]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; fertilization [GO:0009566]; keratinocyte differentiation [GO:0030216]; multicellular organism growth [GO:0035264]; negative regulation of cell migration [GO:0030336]; regulation of cytoskeleton organization [GO:0051493]; regulation of ion transmembrane transport [GO:0034765]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; vacuolar acidification [GO:0007035]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	actin cytoskeleton [GO:0015629]; apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; centrosome [GO:0005813]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; microvillus [GO:0005902]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2d31d2_d1fnea2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2d3ia1_d4f18a1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; phosphate ion binding [GO:0042301]; phosphate ion transmembrane transport [GO:0035435]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	phosphate ion transmembrane transport [GO:0035435]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]	phosphate ion binding [GO:0042301]
d2d3ia1_d4ohna___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]		acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]		cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]		ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]	
d2d3kb__d3erja2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	cytoplasm [GO:0005737]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA hydrolase activity [GO:0004045]	aminoacyl-tRNA hydrolase activity [GO:0004045]
d2d3la2_d2j25a2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]; starch catabolic process [GO:0005983]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	starch catabolic process [GO:0005983]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d2d3rd__d5jp5d___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; lymphatic endothelial cell migration [GO:1904977]		lymphatic endothelial cell migration [GO:1904977]		cytoplasm [GO:0005737]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d2d3sa__d5joza2__1	Viridiplantae		Streptophyta	Bacteroidetes	carbohydrate binding [GO:0030246]	periplasmic space [GO:0042597]; alpha-L-arabinofuranosidase activity [GO:0046556]; symbiotic process benefiting host [GO:0085030]; xyloglucan catabolic process [GO:2000899]		symbiotic process benefiting host [GO:0085030]; xyloglucan catabolic process [GO:2000899]		periplasmic space [GO:0042597]	carbohydrate binding [GO:0030246]	alpha-L-arabinofuranosidase activity [GO:0046556]
d2d3sb__d2r1de1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]		angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]		axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	carbohydrate binding [GO:0030246]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]
d2d3ta3_d4xiyb1__1			Proteobacteria	Proteobacteria	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	fatty acid beta-oxidation [GO:0006635]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	fatty acid beta-oxidation multienzyme complex [GO:0036125]		3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]
d2d3tb4_d1hzde___1		Metazoa	Proteobacteria	Chordata	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	fatty acid beta-oxidation [GO:0006635]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]
d2d3tb4_d1xnyb2__1			Proteobacteria	Actinobacteria	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation [GO:0006635]	fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	acetyl-CoA carboxylase complex [GO:0009317]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]
d2d3td2_d4o99a1__1			Proteobacteria	Proteobacteria	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid beta-oxidation [GO:0006635]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	cytoplasm [GO:0005737]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2d3wa__d1m1ym___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; iron-sulfur cluster assembly [GO:0016226]; response to radiation [GO:0009314]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	iron-sulfur cluster assembly [GO:0016226]; response to radiation [GO:0009314]	nitrogen fixation [GO:0009399]	cytosol [GO:0005829]	molybdenum-iron nitrogenase complex [GO:0016612]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2d4ac2_d3czmb2__1			Crenarchaeota	Apicomplexa	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]			oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	L-lactate dehydrogenase activity [GO:0004459]
d2d4ac2_d3tl2a2__1			Crenarchaeota	Firmicutes	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	L-malate dehydrogenase activity [GO:0030060]; malic enzyme activity [GO:0004470]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]			oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	L-malate dehydrogenase activity [GO:0030060]; malic enzyme activity [GO:0004470]
d2d4eb__d3injh___1		Metazoa	Deinococcus-Thermus	Chordata	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity [GO:0018480]; nucleotide binding [GO:0000166]; 4-hydroxyphenylacetate catabolic process [GO:1901023]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	4-hydroxyphenylacetate catabolic process [GO:1901023]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity [GO:0018480]; nucleotide binding [GO:0000166]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2d4eb__d3rhqb___1		Metazoa	Deinococcus-Thermus	Chordata	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity [GO:0018480]; nucleotide binding [GO:0000166]; 4-hydroxyphenylacetate catabolic process [GO:1901023]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	4-hydroxyphenylacetate catabolic process [GO:1901023]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity [GO:0018480]; nucleotide binding [GO:0000166]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]
d2d4ed__d1o02e___1		Metazoa	Deinococcus-Thermus	Chordata	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity [GO:0018480]; nucleotide binding [GO:0000166]; 4-hydroxyphenylacetate catabolic process [GO:1901023]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	4-hydroxyphenylacetate catabolic process [GO:1901023]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity [GO:0018480]; nucleotide binding [GO:0000166]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2d4fa2_d1miel1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2d4ja__d5khza___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2d4pa1_d1pu9a___1		Fungi	Deinococcus-Thermus	Ascomycota	N-acetyltransferase activity [GO:0008080]	CENP-A containing nucleosome [GO:0043505]; nuclear nucleosome [GO:0000788]; nucleus [GO:0005634]; replication fork protection complex [GO:0031298]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin assembly or disassembly [GO:0006333]; global genome nucleotide-excision repair [GO:0070911]; rRNA transcription [GO:0009303]; sexual sporulation resulting in formation of a cellular spore [GO:0043935]		chromatin assembly or disassembly [GO:0006333]; global genome nucleotide-excision repair [GO:0070911]; rRNA transcription [GO:0009303]; sexual sporulation resulting in formation of a cellular spore [GO:0043935]		CENP-A containing nucleosome [GO:0043505]; nuclear nucleosome [GO:0000788]; nucleus [GO:0005634]; replication fork protection complex [GO:0031298]	N-acetyltransferase activity [GO:0008080]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2d4ua1_d1vltb___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]; protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cell motility [GO:0048870]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; protein homooligomerization [GO:0051260]; receptor clustering [GO:0043113]; regulation of bacterial-type flagellum-dependent cell motility [GO:1902021]; regulation of chemotaxis [GO:0050920]; regulation of protein histidine kinase activity [GO:0032110]; response to amino acid [GO:0043200]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; transmembrane signaling receptor activity [GO:0004888]; chemotaxis [GO:0006935]; signal transduction [GO:0007165]	cell motility [GO:0048870]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; protein homooligomerization [GO:0051260]; receptor clustering [GO:0043113]; regulation of bacterial-type flagellum-dependent cell motility [GO:1902021]; regulation of chemotaxis [GO:0050920]; regulation of protein histidine kinase activity [GO:0032110]; response to amino acid [GO:0043200]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]	protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]	transmembrane signaling receptor activity [GO:0004888]
d2d4vd__d6icda___1			Proteobacteria	Proteobacteria	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d2d4wa1_d3qica1__1		Metazoa		Chordata		cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]		calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]		cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]		ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]
d2d4wa2_d2w40b1__1				Apicomplexa		mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]		glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]		mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d2d4wa2_d3h45d2__1				Firmicutes		ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]		glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]				ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d2d4wb1_d3cqxb1__1		Metazoa		Chordata		axon [GO:0030424]; chaperone complex [GO:0101031]; dendrite [GO:0030425]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; tau protein binding [GO:0048156]; ubiquitin protein ligase binding [GO:0031625]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein processing [GO:0010954]; protein metabolic process [GO:0019538]; protein stabilization [GO:0050821]		negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein processing [GO:0010954]; protein metabolic process [GO:0019538]; protein stabilization [GO:0050821]		axon [GO:0030424]; chaperone complex [GO:0101031]; dendrite [GO:0030425]		adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; tau protein binding [GO:0048156]; ubiquitin protein ligase binding [GO:0031625]
d2d51b2_d1txtd2__1	Viridiplantae		Streptophyta	Firmicutes	protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	flavonoid biosynthetic process [GO:0009813]	isoprenoid biosynthetic process [GO:0008299]			protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d2d52a2_d4ewpc2__1	Viridiplantae		Streptophyta	Actinobacteria	protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]	protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2d52b2_d1teea2__1	Viridiplantae		Streptophyta	Actinobacteria	protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	flavonoid biosynthetic process [GO:0009813]	chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]			protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2d59a__d4xdya1__1			Euryarchaeota		cofactor binding [GO:0048037]; metal ion binding [GO:0046872]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]			cofactor binding [GO:0048037]; metal ion binding [GO:0046872]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]
d2d5ja__d2zbla1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; polysaccharide catabolic process [GO:0000272]	sulfoquinovose isomerase activity [GO:0061593]; 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde [GO:0061720]	polysaccharide catabolic process [GO:0000272]	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde [GO:0061720]	cytoplasm [GO:0005737]		hydrolase activity, acting on glycosyl bonds [GO:0016798]	sulfoquinovose isomerase activity [GO:0061593]
d2d5kd1_d2x177___1			Firmicutes	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d2d5na1_d4elhg1__1			Firmicutes	Firmicutes	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	riboflavin biosynthetic process [GO:0009231]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d2d5nb2_d1wwrd___1			Firmicutes	Aquificae	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	tRNA-specific adenosine-34 deaminase complex [GO:0052718]; tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	riboflavin biosynthetic process [GO:0009231]	tRNA wobble adenosine to inosine editing [GO:0002100]		tRNA-specific adenosine-34 deaminase complex [GO:0052718]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]
d2d5vb1_d2o49a2__1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; cell differentiation [GO:0030154]; glucose metabolic process [GO:0006006]; positive regulation of transcription by RNA polymerase II [GO:0045944]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear heterochromatin [GO:0005720]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; activated T cell proliferation [GO:0050798]; CD4-positive, alpha-beta T cell differentiation [GO:0043367]; CD8-positive, alpha-beta T cell differentiation [GO:0043374]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; epidermis development [GO:0008544]; histone methylation [GO:0016571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; reflex [GO:0060004]; viral process [GO:0016032]	cell differentiation [GO:0030154]; glucose metabolic process [GO:0006006]; positive regulation of transcription by RNA polymerase II [GO:0045944]	activated T cell proliferation [GO:0050798]; CD4-positive, alpha-beta T cell differentiation [GO:0043367]; CD8-positive, alpha-beta T cell differentiation [GO:0043374]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; epidermis development [GO:0008544]; histone methylation [GO:0016571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; reflex [GO:0060004]; viral process [GO:0016032]	nucleus [GO:0005634]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear heterochromatin [GO:0005720]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]	chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d2d5xb__d5aqdj___1	Metazoa		Chordata	Cyanobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2d5zc__d1qpwd___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2d5zc__d4f6ba___1	Metazoa	Metazoa	Chordata	Nemertea (ribbon worms)	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2d60d__d2vmlg___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2d61a__d3eiab1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d2d66a__d4tmrb___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d2d69e2_d3wqpf1__1			Euryarchaeota	Euryarchaeota	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]			magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2d6ba__d3sb8a1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2d6kb__d1bxhd___1	Metazoa	Viridiplantae	Chordata	Streptophyta	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; enzyme binding [GO:0019899]; galactoside binding [GO:0016936]; protein serine/threonine kinase activator activity [GO:0043539]; signaling receptor binding [GO:0005102]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 3 signaling pathway [GO:0034138]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 3 signaling pathway [GO:0034138]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; enzyme binding [GO:0019899]; galactoside binding [GO:0016936]; protein serine/threonine kinase activator activity [GO:0043539]; signaling receptor binding [GO:0005102]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2d6ma1_d3b01a___1	Metazoa		Chordata	Thermotogae	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; enzyme binding [GO:0019899]; galactoside binding [GO:0016936]; protein serine/threonine kinase activator activity [GO:0043539]; signaling receptor binding [GO:0005102]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 3 signaling pathway [GO:0034138]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 3 signaling pathway [GO:0034138]	carbohydrate metabolic process [GO:0005975]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; enzyme binding [GO:0019899]; galactoside binding [GO:0016936]; protein serine/threonine kinase activator activity [GO:0043539]; signaling receptor binding [GO:0005102]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2d6mb1_d1v6ic___1	Metazoa	Viridiplantae	Chordata	Streptophyta	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; enzyme binding [GO:0019899]; galactoside binding [GO:0016936]; protein serine/threonine kinase activator activity [GO:0043539]; signaling receptor binding [GO:0005102]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 3 signaling pathway [GO:0034138]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 3 signaling pathway [GO:0034138]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; enzyme binding [GO:0019899]; galactoside binding [GO:0016936]; protein serine/threonine kinase activator activity [GO:0043539]; signaling receptor binding [GO:0005102]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2d6na1_d3l2yc___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; enzyme binding [GO:0019899]; galactoside binding [GO:0016936]; protein serine/threonine kinase activator activity [GO:0043539]; signaling receptor binding [GO:0005102]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 3 signaling pathway [GO:0034138]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 3 signaling pathway [GO:0034138]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; enzyme binding [GO:0019899]; galactoside binding [GO:0016936]; protein serine/threonine kinase activator activity [GO:0043539]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d2d6nb1_d3boda1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; enzyme binding [GO:0019899]; galactoside binding [GO:0016936]; protein serine/threonine kinase activator activity [GO:0043539]; signaling receptor binding [GO:0005102]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 3 signaling pathway [GO:0034138]	cell junction [GO:0030054]; cell projection [GO:0042995]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; integral component of presynaptic active zone membrane [GO:0099059]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; vesicle [GO:0031982]; acetylcholine receptor binding [GO:0033130]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; type 1 fibroblast growth factor receptor binding [GO:0005105]; adult behavior [GO:0030534]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; learning [GO:0007612]; negative regulation of gene expression [GO:0010629]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; neurotransmitter secretion [GO:0007269]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein heterotetramerization [GO:0051290]; regulation of grooming behavior [GO:2000821]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of postsynaptic density assembly [GO:0099151]; regulation of postsynaptic specialization assembly [GO:0099150]; regulation of presynapse assembly [GO:1905606]; regulation of synaptic vesicle cycle [GO:0098693]; signal transduction [GO:0007165]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by endocannabinoid [GO:0099542]; vesicle docking involved in exocytosis [GO:0006904]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625]	cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 3 signaling pathway [GO:0034138]	adult behavior [GO:0030534]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; learning [GO:0007612]; negative regulation of gene expression [GO:0010629]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; neurotransmitter secretion [GO:0007269]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein heterotetramerization [GO:0051290]; regulation of grooming behavior [GO:2000821]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of postsynaptic density assembly [GO:0099151]; regulation of postsynaptic specialization assembly [GO:0099150]; regulation of presynapse assembly [GO:1905606]; regulation of synaptic vesicle cycle [GO:0098693]; signal transduction [GO:0007165]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by endocannabinoid [GO:0099542]; vesicle docking involved in exocytosis [GO:0006904]; vocalization behavior [GO:0071625]; vocal learning [GO:0042297]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]	cell junction [GO:0030054]; cell projection [GO:0042995]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; integral component of presynaptic active zone membrane [GO:0099059]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; vesicle [GO:0031982]	carbohydrate binding [GO:0030246]; enzyme binding [GO:0019899]; galactoside binding [GO:0016936]; protein serine/threonine kinase activator activity [GO:0043539]; signaling receptor binding [GO:0005102]	acetylcholine receptor binding [GO:0033130]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; type 1 fibroblast growth factor receptor binding [GO:0005105]
d2d6ox1_d5duub___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; enzyme binding [GO:0019899]; galactoside binding [GO:0016936]; protein serine/threonine kinase activator activity [GO:0043539]; signaling receptor binding [GO:0005102]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 3 signaling pathway [GO:0034138]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]	cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 3 signaling pathway [GO:0034138]	cell adhesion [GO:0007155]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; enzyme binding [GO:0019899]; galactoside binding [GO:0016936]; protein serine/threonine kinase activator activity [GO:0043539]; signaling receptor binding [GO:0005102]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2d7fa__d3w59b___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d2d7fl__d2a3wq___1	Viridiplantae	Metazoa	Streptophyta	Chordata	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d2d7ja__d2aumb2__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; glutamine metabolic process [GO:0006541]	cytoplasm [GO:0005737]; carboxypeptidase activity [GO:0004180]; serine-type peptidase activity [GO:0008236]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]	glutamine metabolic process [GO:0006541]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]	carboxypeptidase activity [GO:0004180]; serine-type peptidase activity [GO:0008236]
d2d7th__d3bz4g1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2d7tl1_d1d5il1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2d80a1_d4ffvb2__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]		cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	hydrolase activity [GO:0016787]	collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d2d87a1_d1pa7a___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; filamentous actin [GO:0031941]; microtubule organizing center [GO:0005815]; actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; actin cytoskeleton organization [GO:0030036]; muscle organ development [GO:0007517]; smooth muscle contraction [GO:0006939]	cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; cell division [GO:0051301]; cell migration [GO:0016477]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of cell migration [GO:0030335]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	actin cytoskeleton organization [GO:0030036]; muscle organ development [GO:0007517]; smooth muscle contraction [GO:0006939]	cell division [GO:0051301]; cell migration [GO:0016477]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of cell migration [GO:0030335]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; filamentous actin [GO:0031941]; microtubule organizing center [GO:0005815]	cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]	actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d2d88a1_d1dxxc2__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; Flemming body [GO:0090543]; intercellular bridge [GO:0045171]; microtubule organizing center [GO:0005815]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819]; actin binding [GO:0003779]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; Rab GTPase binding [GO:0017137]; actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; cell cycle [GO:0007049]; cell division [GO:0051301]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cell surface [GO:0009986]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]; actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein localization [GO:0034613]; cellular protein-containing complex assembly [GO:0034622]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; cell cycle [GO:0007049]; cell division [GO:0051301]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887]; oxidation-reduction process [GO:0055114]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein-containing complex assembly [GO:0034622]; cellular protein localization [GO:0034613]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; Flemming body [GO:0090543]; intercellular bridge [GO:0045171]; microtubule organizing center [GO:0005815]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819]	cell [GO:0005623]; cell-substrate junction [GO:0030055]; cell surface [GO:0009986]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]	actin binding [GO:0003779]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; Rab GTPase binding [GO:0017137]	actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]
d2d8ca1_d2qara___1	Metazoa		Chordata		endoplasmic reticulum [GO:0005783]; Golgi trans cisterna [GO:0000138]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]; integral component of plasma membrane [GO:0005887]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ceramide cholinephosphotransferase activity [GO:0047493]; ceramide phosphoethanolamine synthase activity [GO:0002950]; kinase activity [GO:0016301]; sphingomyelin synthase activity [GO:0033188]; apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; inflammatory response [GO:0006954]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of gene expression [GO:0010628]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; inflammatory response [GO:0006954]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of gene expression [GO:0010628]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	endoplasmic reticulum [GO:0005783]; Golgi trans cisterna [GO:0000138]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]; integral component of plasma membrane [GO:0005887]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	host cell cytoplasm [GO:0030430]	ceramide cholinephosphotransferase activity [GO:0047493]; ceramide phosphoethanolamine synthase activity [GO:0002950]; kinase activity [GO:0016301]; sphingomyelin synthase activity [GO:0033188]	lysozyme activity [GO:0003796]
d2d8da1_d5go2b___1			Deinococcus-Thermus	Firmicutes	aldehyde-lyase activity [GO:0016832]; transferase activity [GO:0016740]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			aldehyde-lyase activity [GO:0016832]; transferase activity [GO:0016740]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; chorismate mutase activity [GO:0004106]
d2d92a1_d2i0lb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]		ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]
d2d99a1_d2d9ba1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription by RNA polymerase II [GO:0006366]; transition between slow and fast fiber [GO:0014886]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription by RNA polymerase II [GO:0006366]; transition between slow and fast fiber [GO:0014886]	negative regulation of angiogenesis [GO:0016525]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2d9ca1_d1qkzh2__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; signal transduction [GO:0007165]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]	cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; signal transduction [GO:0007165]	pathogenesis [GO:0009405]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]		IgG binding [GO:0019864]
d2d9qa__d5d72a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]	cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]	cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]
d2d9qb3_d3ncfb2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]	hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]
d2d9ya1_d1mk9d2__1	Metazoa	Metazoa	Chordata	Chordata		alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]		activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]		alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]		cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]
d2dada1_d1okia2__1	Metazoa	Metazoa	Chordata	Chordata	carbohydrate binding [GO:0030246]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			carbohydrate binding [GO:0030246]	structural constituent of eye lens [GO:0005212]
d2daoa1_d4a5nc___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription by RNA polymerase II [GO:0006357]; vitellogenesis [GO:0007296]	DNA binding [GO:0003677]	cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription by RNA polymerase II [GO:0006357]; vitellogenesis [GO:0007296]		cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleus [GO:0005634]		DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	DNA binding [GO:0003677]
d2daza1_d4nnmb1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]; activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]		beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]
d2db5a1_d1v62a1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor signaling complex adaptor activity [GO:0030159]; artery smooth muscle contraction [GO:0014824]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; Notch signaling pathway [GO:0007219]; positive regulation of blood pressure [GO:0045777]; vesicle-mediated transport in synapse [GO:0099003]	bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	artery smooth muscle contraction [GO:0014824]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; Notch signaling pathway [GO:0007219]; positive regulation of blood pressure [GO:0045777]; vesicle-mediated transport in synapse [GO:0099003]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]		receptor signaling complex adaptor activity [GO:0030159]
d2dblh1_d4nx3a4__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2dboa__d3pd4a___1			Aquificae	Euryarchaeota	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; D-tyrosyl-tRNA(Tyr) deacylase activity [GO:0051500]; Gly-tRNA(Ala) hydrolase activity [GO:0106026]; Ser(Gly)-tRNA(Ala) hydrolase activity [GO:0043908]; tRNA binding [GO:0000049]; D-amino acid catabolic process [GO:0019478]; tRNA metabolic process [GO:0006399]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; threonyl-tRNA aminoacylation [GO:0006435]	D-amino acid catabolic process [GO:0019478]; tRNA metabolic process [GO:0006399]	threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; D-tyrosyl-tRNA(Tyr) deacylase activity [GO:0051500]; Gly-tRNA(Ala) hydrolase activity [GO:0106026]; Ser(Gly)-tRNA(Ala) hydrolase activity [GO:0043908]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2dbpa__d1ziua1__1				Proteobacteria		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d2dbta__d4ow1b___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]	hydrolase activity [GO:0016787]
d2dbtb__d1l24a___1			Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]	host cell cytoplasm [GO:0030430]	carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]	lysozyme activity [GO:0003796]
d2dbtc__d1sx7a___1			Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]	host cell cytoplasm [GO:0030430]	carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]	lysozyme activity [GO:0003796]
d2dbvp2_d1drva2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; cellular amino acid biosynthetic process [GO:0008652]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cellular amino acid biosynthetic process [GO:0008652]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]
d2dc2a__d5hdya1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	ion channel binding [GO:0044325]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]
d2dc4a__d3ghxa___1			Euryarchaeota									
d2dcna1_d1gqtb___1			Crenarchaeota	Proteobacteria	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]		D-ribose catabolic process [GO:0019303]		cytosol [GO:0005829]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d2dcnd__d2a9ya___1			Crenarchaeota	Apicomplexa	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]		AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]			2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d2dcng__d1rfta___1		Metazoa	Crenarchaeota	Chordata	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]; pyridoxal 5'-phosphate salvage [GO:0009443]		pyridoxal 5'-phosphate salvage [GO:0009443]		cytoplasm [GO:0005737]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]
d2dcnj__d5c41b1__1		Metazoa	Crenarchaeota	Chordata	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]		D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]		cytosol [GO:0005829]; nucleus [GO:0005634]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d2dcta1_d1ucxc2__1		Viridiplantae	Deinococcus-Thermus	Streptophyta		endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]; nutrient reservoir activity [GO:0045735]				endoplasmic reticulum [GO:0005783]; protein storage vacuole [GO:0000326]		nutrient reservoir activity [GO:0045735]
d2dctb__d3scfb2__1			Deinococcus-Thermus	Actinobacteria		dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]				dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d2dcya__d1dfqa1__1			Firmicutes	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	xylan catabolic process [GO:0045493]	negative regulation of neurotransmitter secretion [GO:0046929]		clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	endo-1,4-beta-xylanase activity [GO:0031176]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d2dcyb__d5ewsc___1		Metazoa	Firmicutes	Chordata	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2dcyc__d1loa.2__1		Viridiplantae	Firmicutes	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	mannose binding [GO:0005537]	xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	mannose binding [GO:0005537]
d2dcyd__d1rita___1		Viridiplantae	Firmicutes	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2dcye__d2e7td___1		Viridiplantae	Firmicutes	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]	xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]
d2dcza__d1ynaa___1		Fungi	Firmicutes	Ascomycota	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d2dcza__d2hyka___1			Firmicutes	Actinobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2dczb__d1redb1__1		Fungi	Firmicutes	Ascomycota	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d2dczb__d2y9la___1			Firmicutes		endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	
d2dd8h2_d1q94a1__1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2dd8l2_d4lhqb___1		Viridiplantae		Streptophyta	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	endoplasmic reticulum [GO:0005783]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]	carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2ddab1_d5vhga___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; protein homodimerization activity [GO:0042803]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]		positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]	extracellular region [GO:0005576]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	protein homodimerization activity [GO:0042803]
d2ddac1_d1xtaa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d2ddfb__d3funa2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2ddql2_d1c1el2__1	Metazoa		Chordata									
d2ddql2_d3ck0l1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ddrd__d3i5vc___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; sphingomyelin phosphodiesterase activity [GO:0004767]; hemolysis in other organism [GO:0044179]	extracellular region [GO:0005576]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; hemolysis in other organism [GO:0044179]	hemolysis in other organism [GO:0044179]	hemolysis in other organism [GO:0044179]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	sphingomyelin phosphodiesterase activity [GO:0004767]	phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]
d2ddya__d5cxaa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d2de6a1_d4hm1a1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	carbazole catabolic process [GO:0046232]	aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]
d2de6a2_d2hmla2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	carbazole catabolic process [GO:0046232]	aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]
d2de6a2_d2xsoe2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	carbazole catabolic process [GO:0046232]	aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2de6b1_d1sjga___1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; toluene catabolic process [GO:0042203]	carbazole catabolic process [GO:0046232]	toluene catabolic process [GO:0042203]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2de6c1_d1z02e1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	carbazole catabolic process [GO:0046232]				2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d2de6c1_d2a06r2__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	carbazole catabolic process [GO:0046232]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d2de7a2_d2xr8s2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	carbazole catabolic process [GO:0046232]	aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2de7b1_d1eg9a1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	carbazole catabolic process [GO:0046232]	aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]
d2de8a__d1a0h.2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]
d2deca__d1dqra___1		Metazoa	Euryarchaeota	Chordata	carbohydrate derivative binding [GO:0097367]; carbohydrate derivative metabolic process [GO:1901135]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	carbohydrate derivative metabolic process [GO:1901135]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]; extracellular space [GO:0005615]	carbohydrate derivative binding [GO:0097367]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]
d2degb__d2yj0f___1			Deinococcus-Thermus	Actinobacteria	nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2dehb__d2yj0a___1			Deinococcus-Thermus	Actinobacteria		extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]		nucleotide binding [GO:0000166]
d2dehe__d3oqth___1			Deinococcus-Thermus	Actinobacteria		extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]		nucleotide binding [GO:0000166]
d2deia1_d2wnra1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; galactokinase activity [GO:0004335]; galactose binding [GO:0005534]; magnesium ion binding [GO:0000287]; galactose metabolic process [GO:0006012]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	galactose metabolic process [GO:0006012]	RNA catabolic process [GO:0006401]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	ATP binding [GO:0005524]; galactokinase activity [GO:0004335]; galactose binding [GO:0005534]; magnesium ion binding [GO:0000287]	3'-5'-exoribonuclease activity [GO:0000175]
d2depb__d1r86a1__1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; endo-1,4-beta-xylanase activity [GO:0031176]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	cellulase activity [GO:0008810]; endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d2depb__d3amdb___1			Firmicutes	Thermotogae	cellulase activity [GO:0008810]; endo-1,4-beta-xylanase activity [GO:0031176]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	cellular glucan metabolic process [GO:0006073]		extracellular region [GO:0005576]	cellulase activity [GO:0008810]; endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2deqa1_d1nnha___1			Euryarchaeota	Euryarchaeota	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; tRNA aminoacylation for protein translation [GO:0006418]	cellular protein modification process [GO:0006464]	tRNA aminoacylation for protein translation [GO:0006418]			ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]
d2deva__d2yizd___1			Deinococcus-Thermus	Actinobacteria		extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]		nucleotide binding [GO:0000166]
d2dewx3_d4bofc___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; arginine binding [GO:0034618]; arginine deiminase activity [GO:0016990]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular protein modification process [GO:0006464]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; innate immune response [GO:0045087]; nucleosome assembly [GO:0006334]; protein citrullination [GO:0018101]; stem cell population maintenance [GO:0019827]	cytoplasm [GO:0005737]; arginine deiminase activity [GO:0016990]; arginine catabolic process to ornithine [GO:0019547]	cellular protein modification process [GO:0006464]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; innate immune response [GO:0045087]; nucleosome assembly [GO:0006334]; protein citrullination [GO:0018101]; stem cell population maintenance [GO:0019827]	arginine catabolic process to ornithine [GO:0019547]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; arginine deiminase activity [GO:0016990]; calcium ion binding [GO:0005509]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]	arginine deiminase activity [GO:0016990]
d2df1a__d3zwxf___1		Metazoa		Mollusca		cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]		single fertilization [GO:0007338]		cytoplasmic vesicle [GO:0031410]		NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]
d2df5b__d1augc___1			Euryarchaeota	Firmicutes	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d2df5b__d2ebjb___1			Euryarchaeota	Deinococcus-Thermus	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d2df7l__d2gsyf___1					host cell cytoplasm [GO:0030430]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; viral capsid [GO:0019028]; host cell surface binding [GO:0046812]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]	host cell cytoplasm [GO:0030430]; T=13 icosahedral viral capsid [GO:0039621]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]			host cell cytoplasm [GO:0030430]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; viral capsid [GO:0019028]	host cell cytoplasm [GO:0030430]; T=13 icosahedral viral capsid [GO:0039621]	host cell surface binding [GO:0046812]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]
d2df7t__d1vbe1___1					host cell cytoplasm [GO:0030430]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; viral capsid [GO:0019028]; host cell surface binding [GO:0046812]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell surface binding [GO:0046812]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2dfba__d3pvnq___1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	xylan catabolic process [GO:0045493]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	endo-1,4-beta-xylanase activity [GO:0031176]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d2dfda2_d3d4pb2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]	L-lactate dehydrogenase activity [GO:0004459]
d2dfdb1_d1e3la2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; all-trans retinal binding [GO:0005503]; benzaldehyde dehydrogenase [NAD(P)+] activity [GO:0019115]; ethanol binding [GO:0035276]; NAD binding [GO:0051287]; NADPH:quinone reductase activity [GO:0003960]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; quinone metabolic process [GO:1901661]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; cellular aldehyde metabolic process [GO:0006081]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; quinone metabolic process [GO:1901661]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; all-trans retinal binding [GO:0005503]; benzaldehyde dehydrogenase [NAD(P)+] activity [GO:0019115]; ethanol binding [GO:0035276]; NAD binding [GO:0051287]; NADPH:quinone reductase activity [GO:0003960]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]
d2dfdd1_d1nqtd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d2dfdd1_d3vkuf1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]	
d2dfdd2_d3zznb2__1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]	L-lactate dehydrogenase activity [GO:0004459]
d2dfoa__d4xs0b___1		Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2dfob__d5c6eb___1		Metazoa		Chordata		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2dfsc1_d1psra___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]	calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d2dfsd1_d4phnb___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; proteolysis [GO:0006508]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	proteolysis [GO:0006508]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d2dfse1_d2h61b___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d2dfsf1_d2kdua___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	calcium-mediated signaling [GO:0019722]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]		adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]
d2dfsn1_d1cfpb___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d2dfsp1_d5csfa1__1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d2dfsq1_d2m1kb___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; advanced glycation end-product receptor activity [GO:0050785]; amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; S100 protein binding [GO:0044548]; scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; astrocyte activation [GO:0048143]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; glucose mediated signaling pathway [GO:0010255]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of blood circulation [GO:1903523]; negative regulation of connective tissue replacement involved in inflammatory response wound healing [GO:1904597]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of long-term synaptic potentiation [GO:1900272]; neuron projection development [GO:0031175]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein localization to membrane [GO:0072657]; regulation of CD4-positive, alpha-beta T cell activation [GO:2000514]; regulation of DNA binding [GO:0051101]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of p38MAPK cascade [GO:1900744]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell mediated cytotoxicity [GO:0001914]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to wounding [GO:0009611]; transcytosis [GO:0045056]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	astrocyte activation [GO:0048143]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; glucose mediated signaling pathway [GO:0010255]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of blood circulation [GO:1903523]; negative regulation of connective tissue replacement involved in inflammatory response wound healing [GO:1904597]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of long-term synaptic potentiation [GO:1900272]; neuron projection development [GO:0031175]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein localization to membrane [GO:0072657]; regulation of CD4-positive, alpha-beta T cell activation [GO:2000514]; regulation of DNA binding [GO:0051101]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of p38MAPK cascade [GO:1900744]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell mediated cytotoxicity [GO:0001914]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to wounding [GO:0009611]; transcytosis [GO:0045056]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]	advanced glycation end-product receptor activity [GO:0050785]; amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; S100 protein binding [GO:0044548]; scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]
d2dfss1_d3ko0k___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrial membrane [GO:0031966]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; synaptic vesicle membrane [GO:0030672]; voltage-gated potassium channel complex [GO:0008076]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d2dftd__d3lw8d1__1		Metazoa	Actinobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cytosol [GO:0005829]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d2dfza__d2xxib1__1		Metazoa		Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2dfzb__d1mxva___1		Metazoa		Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2dg1a2_d5d9ca___1		Metazoa	Firmicutes	Arthropoda	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]			cytoplasm [GO:0005737]		hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2dg1f2_d2iawa___1		Metazoa	Firmicutes	Mollusca	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]			cytoplasm [GO:0005737]		hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]
d2dgeb__d1mg3d___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid lumen [GO:0009543]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem I [GO:0009773]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	photosynthetic electron transport in photosystem I [GO:0009773]		chloroplast thylakoid lumen [GO:0009543]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2dgmb__d2bwpe___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]; protoporphyrinogen IX biosynthetic process [GO:0006782]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	protoporphyrinogen IX biosynthetic process [GO:0006782]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]	5-aminolevulinate synthase activity [GO:0003870]; pyridoxal phosphate binding [GO:0030170]
d2dgoa1_d2cpxa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; apoptotic process [GO:0006915]; negative regulation of cytokine biosynthetic process [GO:0042036]; negative regulation of translation [GO:0017148]; positive regulation of epithelial cell apoptotic process [GO:1904037]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of mRNA splicing, via spliceosome [GO:0048024]	RNA binding [GO:0003723]	apoptotic process [GO:0006915]; negative regulation of cytokine biosynthetic process [GO:0042036]; negative regulation of translation [GO:0017148]; positive regulation of epithelial cell apoptotic process [GO:1904037]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of mRNA splicing, via spliceosome [GO:0048024]		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]		mRNA 3'-UTR AU-rich region binding [GO:0035925]	RNA binding [GO:0003723]
d2dgsa1_d4ckod4__1	Metazoa		Chordata		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(G) binding [GO:0034046]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; RNA stem-loop binding [GO:0035613]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; maternal placenta development [GO:0001893]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; spermatogenesis [GO:0007283]		cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; maternal placenta development [GO:0001893]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; spermatogenesis [GO:0007283]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]		mRNA 3'-UTR binding [GO:0003730]; poly(G) binding [GO:0034046]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; RNA stem-loop binding [GO:0035613]	
d2dgta1_d5o2va___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of gene expression [GO:0010628]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; negative regulation of cytokine biosynthetic process [GO:0042036]; negative regulation of translation [GO:0017148]; positive regulation of epithelial cell apoptotic process [GO:1904037]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of mRNA splicing, via spliceosome [GO:0048024]	circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of gene expression [GO:0010628]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]	apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; negative regulation of cytokine biosynthetic process [GO:0042036]; negative regulation of translation [GO:0017148]; positive regulation of epithelial cell apoptotic process [GO:1904037]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of mRNA splicing, via spliceosome [GO:0048024]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	mRNA 3'-UTR AU-rich region binding [GO:0035925]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d2dgua1_d2la6a1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; CRD-mediated mRNA stability complex [GO:0070937]; endoplasmic reticulum [GO:0005783]; GAIT complex [GO:0097452]; histone pre-mRNA 3'end processing complex [GO:0071204]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 5'-UTR binding [GO:0048027]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; cellular response to interferon-gamma [GO:0071346]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of translation [GO:0017148]; osteoblast differentiation [GO:0001649]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; viral process [GO:0016032]	dendritic spine head [GO:0044327]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; estrogen receptor binding [GO:0030331]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; myosin V binding [GO:0031489]; retinoid X receptor binding [GO:0046965]; RNA binding [GO:0003723]; thyroid hormone receptor binding [GO:0046966]; transcription coactivator activity [GO:0003713]; cellular response to calcium ion [GO:0071277]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein homooligomerization [GO:0051260]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]	cellular response to interferon-gamma [GO:0071346]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of translation [GO:0017148]; osteoblast differentiation [GO:0001649]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; viral process [GO:0016032]	cellular response to calcium ion [GO:0071277]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein homooligomerization [GO:0051260]; regulation of RNA splicing [GO:0043484]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA splicing [GO:0008380]	catalytic step 2 spliceosome [GO:0071013]; CRD-mediated mRNA stability complex [GO:0070937]; endoplasmic reticulum [GO:0005783]; GAIT complex [GO:0097452]; histone pre-mRNA 3'end processing complex [GO:0071204]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	dendritic spine head [GO:0044327]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]	mRNA 5'-UTR binding [GO:0048027]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; estrogen receptor binding [GO:0030331]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; myosin V binding [GO:0031489]; retinoid X receptor binding [GO:0046965]; RNA binding [GO:0003723]; thyroid hormone receptor binding [GO:0046966]; transcription coactivator activity [GO:0003713]
d2dh0a2_d1jt0a2__1				Firmicutes		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]		negative regulation of transcription, DNA-templated [GO:0045892]				DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2dh7a1_d1wi6a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; DNA binding [GO:0003677]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; defense response [GO:0006952]; fibroblast growth factor receptor signaling pathway [GO:0008543]; germ cell development [GO:0007281]; positive regulation of cell population proliferation [GO:0008284]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell division [GO:0017145]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; RNA binding [GO:0003723]	apoptotic process [GO:0006915]; defense response [GO:0006952]; fibroblast growth factor receptor signaling pathway [GO:0008543]; germ cell development [GO:0007281]; positive regulation of cell population proliferation [GO:0008284]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell division [GO:0017145]		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	DNA binding [GO:0003677]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d2dh7a1_d2do4a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; DNA binding [GO:0003677]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; defense response [GO:0006952]; fibroblast growth factor receptor signaling pathway [GO:0008543]; germ cell development [GO:0007281]; positive regulation of cell population proliferation [GO:0008284]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell division [GO:0017145]	ASAP complex [GO:0061574]; Cajal body [GO:0015030]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone binding [GO:0042393]; RNA binding [GO:0003723]; U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070]; U6atac snRNA binding [GO:0030624]; ubiquitin-specific protease binding [GO:1990381]; cell morphogenesis [GO:0000902]; hematopoietic stem cell proliferation [GO:0071425]; homeostasis of number of cells [GO:0048872]; mRNA splicing, via spliceosome [GO:0000398]; nucleosome assembly [GO:0006334]; positive regulation of histone deubiquitination [GO:1903586]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; spliceosomal tri-snRNP complex assembly [GO:0000244]	apoptotic process [GO:0006915]; defense response [GO:0006952]; fibroblast growth factor receptor signaling pathway [GO:0008543]; germ cell development [GO:0007281]; positive regulation of cell population proliferation [GO:0008284]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell division [GO:0017145]	cell morphogenesis [GO:0000902]; hematopoietic stem cell proliferation [GO:0071425]; homeostasis of number of cells [GO:0048872]; mRNA splicing, via spliceosome [GO:0000398]; nucleosome assembly [GO:0006334]; positive regulation of histone deubiquitination [GO:1903586]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; spliceosomal tri-snRNP complex assembly [GO:0000244]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	ASAP complex [GO:0061574]; Cajal body [GO:0015030]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]	histone binding [GO:0042393]; RNA binding [GO:0003723]; U4 snRNA binding [GO:0030621]; U6atac snRNA binding [GO:0030624]; U6 snRNA binding [GO:0017070]; ubiquitin-specific protease binding [GO:1990381]
d2dh9a1_d1x4ca1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; post-mRNA release spliceosomal complex [GO:0071014]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; alternative mRNA splicing, via spliceosome [GO:0000380]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA stability involved in response to oxidative stress [GO:2000815]; RNA metabolic process [GO:0016070]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA topoisomerase binding [GO:0044547]; mRNA binding [GO:0003729]; protein kinase B binding [GO:0043422]; RNA binding [GO:0003723]; RS domain binding [GO:0050733]; alternative mRNA splicing, via spliceosome [GO:0000380]; cardiac muscle contraction [GO:0060048]; in utero embryonic development [GO:0001701]; liver regeneration [GO:0097421]; mRNA 5'-splice site recognition [GO:0000395]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA transport [GO:0051028]; oligodendrocyte differentiation [GO:0048709]; positive regulation of RNA splicing [GO:0033120]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	alternative mRNA splicing, via spliceosome [GO:0000380]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA stability involved in response to oxidative stress [GO:2000815]; RNA metabolic process [GO:0016070]	alternative mRNA splicing, via spliceosome [GO:0000380]; cardiac muscle contraction [GO:0060048]; in utero embryonic development [GO:0001701]; liver regeneration [GO:0097421]; mRNA 5'-splice site recognition [GO:0000395]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA transport [GO:0051028]; oligodendrocyte differentiation [GO:0048709]; positive regulation of RNA splicing [GO:0033120]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	catalytic step 2 spliceosome [GO:0071013]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; post-mRNA release spliceosomal complex [GO:0071014]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]	DNA topoisomerase binding [GO:0044547]; mRNA binding [GO:0003729]; protein kinase B binding [GO:0043422]; RNA binding [GO:0003723]; RS domain binding [GO:0050733]
d2dhba__d3v58c___1	Metazoa		Chordata	Rhodophyta	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2dhbb__d1o1ma1__1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2dhfa__d2w9ga___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d2dhfb__d4elhc1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d2dhga1_d1u6fa1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; nucleus [GO:0005634]; RNA binding [GO:0003723]; selenocysteine incorporation [GO:0001514]	RNA binding [GO:0003723]	selenocysteine incorporation [GO:0001514]		cytoplasm [GO:0005737]; nucleus [GO:0005634]		RNA binding [GO:0003723]	RNA binding [GO:0003723]
d2dhga1_d5t9pc___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; RNA binding [GO:0003723]; selenocysteine incorporation [GO:0001514]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleus [GO:0005634]; preribosome, large subunit precursor [GO:0030687]; rRNA binding [GO:0019843]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit biogenesis [GO:0042273]	selenocysteine incorporation [GO:0001514]	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit biogenesis [GO:0042273]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleus [GO:0005634]; preribosome, large subunit precursor [GO:0030687]	RNA binding [GO:0003723]	rRNA binding [GO:0019843]
d2diaa1_d5aa7b___1	Metazoa		Chordata	Actinobacteria	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	carbohydrate metabolic process [GO:0005975]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	extracellular region [GO:0005576]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d2dica1_d2dmba1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d2diea2_d1xd1a1__1		Metazoa	Firmicutes	Chordata	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d2diea2_d5e6yb3__1			Firmicutes	Proteobacteria	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]		cytosol [GO:0005829]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2dija3_d3dc0a2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d2dija4_d1j12b2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2dija4_d3aofa___1			Firmicutes	Thermotogae	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2dika1_d2x0sa1__1			Firmicutes		ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]	glycosome [GO:0020015]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; phosphorylation [GO:0016310]; pyruvate metabolic process [GO:0006090]	pyruvate metabolic process [GO:0006090]	phosphorylation [GO:0016310]; pyruvate metabolic process [GO:0006090]		glycosome [GO:0020015]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]
d2dika1_d3eool___1			Firmicutes		ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]		pyruvate metabolic process [GO:0006090]				ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]	
d2diwa1_d1lf8a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mRNA cleavage factor complex [GO:0005849]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA polymerase core enzyme binding [GO:0043175]; RNA polymerase II C-terminal domain phosphoserine binding [GO:1990269]; RNA polymerase II complex binding [GO:0000993]; mRNA polyadenylation [GO:0006378]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; termination of RNA polymerase II transcription [GO:0006369]	early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]; ADP-ribosylation factor binding [GO:0030306]; ubiquitin binding [GO:0043130]; cellular protein metabolic process [GO:0044267]; endocytic recycling [GO:0032456]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; negative regulation of amyloid-beta formation [GO:1902430]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein localization to cell surface [GO:0034394]; protein localization to lysosome [GO:0061462]; regulation of protein stability [GO:0031647]	mRNA polyadenylation [GO:0006378]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; termination of RNA polymerase II transcription [GO:0006369]	cellular protein metabolic process [GO:0044267]; endocytic recycling [GO:0032456]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; negative regulation of amyloid-beta formation [GO:1902430]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein localization to cell surface [GO:0034394]; protein localization to lysosome [GO:0061462]; regulation of protein stability [GO:0031647]	cytoplasm [GO:0005737]; mRNA cleavage factor complex [GO:0005849]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA polymerase core enzyme binding [GO:0043175]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II C-terminal domain phosphoserine binding [GO:1990269]	ADP-ribosylation factor binding [GO:0030306]; ubiquitin binding [GO:0043130]
d2dixa1_d2lupb1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; RISC-loading complex [GO:0070578]; double-stranded RNA binding [GO:0003725]; enzyme activator activity [GO:0008047]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; pre-miRNA binding [GO:0070883]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; cellular response to oxidative stress [GO:0034599]; immune response [GO:0006955]; middle ear morphogenesis [GO:0042474]; miRNA metabolic process [GO:0010586]; negative regulation of cell population proliferation [GO:0008285]; outer ear morphogenesis [GO:0042473]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; response to virus [GO:0009615]; skeletal system morphogenesis [GO:0048705]; viral process [GO:0016032]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; double-stranded RNA binding [GO:0003725]; ribonuclease III activity [GO:0004525]; box C/D snoRNA processing [GO:0034963]; box H/ACA snoRNA processing [GO:0034964]; chromatin organization [GO:0006325]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; pre-miRNA processing [GO:0031054]; primary miRNA processing [GO:0031053]; production of siRNA involved in RNA interference [GO:0030422]; regulation of fungal-type cell wall organization [GO:0060237]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; rRNA transcription [GO:0009303]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	cellular response to oxidative stress [GO:0034599]; immune response [GO:0006955]; middle ear morphogenesis [GO:0042474]; miRNA metabolic process [GO:0010586]; negative regulation of cell population proliferation [GO:0008285]; outer ear morphogenesis [GO:0042473]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; response to virus [GO:0009615]; skeletal system morphogenesis [GO:0048705]; viral process [GO:0016032]	box C/D snoRNA processing [GO:0034963]; box H/ACA snoRNA processing [GO:0034964]; chromatin organization [GO:0006325]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; pre-miRNA processing [GO:0031054]; primary miRNA processing [GO:0031053]; production of siRNA involved in RNA interference [GO:0030422]; regulation of fungal-type cell wall organization [GO:0060237]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; rRNA transcription [GO:0009303]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; RISC-loading complex [GO:0070578]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	double-stranded RNA binding [GO:0003725]; enzyme activator activity [GO:0008047]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; pre-miRNA binding [GO:0070883]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]	double-stranded RNA binding [GO:0003725]; ribonuclease III activity [GO:0004525]
d2dj0a1_d2c0fa2__1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; integral component of membrane [GO:0016021]; cell redox homeostasis [GO:0045454]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; protein homodimerization activity [GO:0042803]; dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	cell redox homeostasis [GO:0045454]	dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	cell [GO:0005623]; integral component of membrane [GO:0016021]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]		protein homodimerization activity [GO:0042803]
d2dj4a1_d2e9ja1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d2dj5b__d2qd2a___1		Metazoa	Euryarchaeota	Chordata	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]; anaerobic cobalamin biosynthetic process [GO:0019251]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	anaerobic cobalamin biosynthetic process [GO:0019251]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d2dj6b__d4d19a2__1		Fungi	Euryarchaeota	Ascomycota	metal ion binding [GO:0046872]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	metal ion binding [GO:0046872]	urate oxidase activity [GO:0004846]
d2dj6b__d4mb8d2__1		Metazoa	Euryarchaeota	Chordata	metal ion binding [GO:0046872]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	metal ion binding [GO:0046872]	urate oxidase activity [GO:0004846]
d2djha__d1v74a___1			Proteobacteria	Proteobacteria	endonuclease activity [GO:0004519]; ribonuclease activity [GO:0004540]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	extrachromosomal circular DNA [GO:0005727]; ribonuclease activity [GO:0004540]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]		extrachromosomal circular DNA [GO:0005727]	endonuclease activity [GO:0004519]; ribonuclease activity [GO:0004540]	ribonuclease activity [GO:0004540]
d2djia1_d4k9oc2__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2djia3_d1qpbb2__1		Fungi	Firmicutes	Ascomycota	magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2djka1_d4zbab1__1	Fungi	Fungi	Ascomycota	Basidiomycota	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]		protein disulfide isomerase activity [GO:0003756]	
d2djxb__d3c61a1__1					cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; nucleotide binding [GO:0000166]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' UMP biosynthetic process [GO:0044205]	'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; nucleotide binding [GO:0000166]
d2dk2a1_d5lsld___1	Metazoa	Fungi	Chordata	Ascomycota	axon terminus [GO:0043679]; catalytic step 2 spliceosome [GO:0071013]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; growth cone [GO:0030426]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; circadian rhythm [GO:0007623]; mRNA destabilization [GO:0061157]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of catalytic activity [GO:0043086]; RNA metabolic process [GO:0016070]	nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]; RNA binding [GO:0003723]; mRNA splicing, via spliceosome [GO:0000398]	circadian rhythm [GO:0007623]; mRNA destabilization [GO:0061157]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of catalytic activity [GO:0043086]; RNA metabolic process [GO:0016070]	mRNA splicing, via spliceosome [GO:0000398]	axon terminus [GO:0043679]; catalytic step 2 spliceosome [GO:0071013]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; growth cone [GO:0030426]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]	mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d2dk3a1_d3dkma1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]; ubiquitin-protein transferase activity [GO:0004842]; aorta development [GO:0035904]; heart valve development [GO:0003170]; protein K63-linked ubiquitination [GO:0070534]; ventricular septum development [GO:0003281]	metal ion binding [GO:0046872]; ubiquitin-protein transferase activity [GO:0004842]; aorta development [GO:0035904]; heart valve development [GO:0003170]; protein K63-linked ubiquitination [GO:0070534]; ventricular septum development [GO:0003281]	aorta development [GO:0035904]; heart valve development [GO:0003170]; protein K63-linked ubiquitination [GO:0070534]; ventricular septum development [GO:0003281]	aorta development [GO:0035904]; heart valve development [GO:0003170]; protein K63-linked ubiquitination [GO:0070534]; ventricular septum development [GO:0003281]			metal ion binding [GO:0046872]; ubiquitin-protein transferase activity [GO:0004842]	metal ion binding [GO:0046872]; ubiquitin-protein transferase activity [GO:0004842]
d2dk8a1_d1fbqa1__1	Metazoa	Fungi	Chordata	Ascomycota	RNA polymerase III complex [GO:0005666]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; double-stranded DNA binding [GO:0003690]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; transcription by RNA polymerase III [GO:0006383]	nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; transcription by RNA polymerase III [GO:0006383]		RNA polymerase III complex [GO:0005666]	nucleus [GO:0005634]; protein-DNA complex [GO:0032993]	DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; double-stranded DNA binding [GO:0003690]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]
d2dk9a1_d5a4bb2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; hippocampal mossy fiber expansion [GO:1990026]; intercellular bridge [GO:0045171]; intermediate filament [GO:0005882]; midbody [GO:0030496]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; SH3 domain binding [GO:0017124]; actin filament bundle assembly [GO:0051017]; actin filament depolymerization [GO:0030042]; blood coagulation [GO:0007596]; cytoskeleton organization [GO:0007010]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of protein phosphorylation [GO:0001933]; oxidation-reduction process [GO:0055114]; regulation of regulated secretory pathway [GO:1903305]; signal transduction [GO:0007165]; sulfur oxidation [GO:0019417]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; pseudopodium [GO:0031143]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]; actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin filament bundle assembly [GO:0051017]; actin filament depolymerization [GO:0030042]; blood coagulation [GO:0007596]; cytoskeleton organization [GO:0007010]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of protein phosphorylation [GO:0001933]; oxidation-reduction process [GO:0055114]; regulation of regulated secretory pathway [GO:1903305]; signal transduction [GO:0007165]; sulfur oxidation [GO:0019417]	actin filament uncapping [GO:0051695]; cardiac muscle cell development [GO:0055013]; cell adhesion [GO:0007155]; focal adhesion assembly [GO:0048041]; MAPK cascade [GO:0000165]; microspike assembly [GO:0030035]; muscle filament sliding [GO:0030049]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein localization to cell surface [GO:2000009]; phospholipase C-activating angiotensin-activated signaling pathway [GO:0086097]; platelet degranulation [GO:0002576]; positive regulation of cation channel activity [GO:2001259]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein homotetramerization [GO:0051289]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of membrane potential [GO:0042391]; regulation of NMDA receptor activity [GO:2000310]; sarcomere organization [GO:0045214]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; hippocampal mossy fiber expansion [GO:1990026]; intercellular bridge [GO:0045171]; intermediate filament [GO:0005882]; midbody [GO:0030496]; plasma membrane [GO:0005886]	actin filament [GO:0005884]; cortical actin cytoskeleton [GO:0030864]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; platelet alpha granule lumen [GO:0031093]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; pseudopodium [GO:0031143]; Z disc [GO:0030018]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; SH3 domain binding [GO:0017124]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; FATZ binding [GO:0051373]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; LIM domain binding [GO:0030274]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; thyroid hormone receptor coactivator activity [GO:0030375]; titin binding [GO:0031432]; titin Z domain binding [GO:0070080]
d2dkgb2_d1e22a2__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	cellular protein modification process [GO:0006464]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]		cytosol [GO:0005829]; membrane [GO:0016020]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]
d2dkjb__d3vaxa___1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	catalytic activity [GO:0003824]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]		cytoplasm [GO:0005737]		glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	catalytic activity [GO:0003824]
d2dkpa1_d5cllb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; postsynaptic density [GO:0014069]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; reproductive system development [GO:0061458]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	reproductive system development [GO:0061458]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; postsynaptic density [GO:0014069]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2dkua1_d1dvfc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2dl2a1_d5mtlc2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; regulation of immune response [GO:0050776]		regulation of immune response [GO:0050776]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]			
d2dl2a2_d2x44d___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; regulation of immune response [GO:0050776]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]		
d2dlfh__d3c5zg1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d2dlfl__d3mgok1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2dlsa1_d2he2a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; actin cytoskeleton organization [GO:0030036]; establishment of cell polarity [GO:0030010]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell growth [GO:0001558]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; striated muscle contraction [GO:0006941]	axon cytoplasm [GO:1904115]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; guanylate kinase activity [GO:0004385]; kinase binding [GO:0019900]; structural constituent of postsynaptic density [GO:0098919]; anterograde axonal protein transport [GO:0099641]; cell-cell adhesion [GO:0098609]; cellular response to potassium ion [GO:0035865]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; MAPK cascade [GO:0000165]; negative regulation of phosphatase activity [GO:0010923]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of NMDA receptor activity [GO:2000310]; retrograde axonal protein transport [GO:0099642]; sensory perception of pain [GO:0019233]	actin cytoskeleton organization [GO:0030036]; establishment of cell polarity [GO:0030010]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell growth [GO:0001558]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; striated muscle contraction [GO:0006941]	anterograde axonal protein transport [GO:0099641]; cell-cell adhesion [GO:0098609]; cellular response to potassium ion [GO:0035865]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; MAPK cascade [GO:0000165]; negative regulation of phosphatase activity [GO:0010923]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of NMDA receptor activity [GO:2000310]; retrograde axonal protein transport [GO:0099642]; sensory perception of pain [GO:0019233]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	axon cytoplasm [GO:1904115]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]	G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]	guanylate kinase activity [GO:0004385]; kinase binding [GO:0019900]; structural constituent of postsynaptic density [GO:0098919]
d2dlta1_d3p0vm1__1	Metazoa		Chordata		cytoskeleton [GO:0005856]; myosin filament [GO:0032982]; actin binding [GO:0003779]; structural constituent of cytoskeleton [GO:0005200]; cell adhesion [GO:0007155]; muscle contraction [GO:0006936]		cell adhesion [GO:0007155]; muscle contraction [GO:0006936]		cytoskeleton [GO:0005856]; myosin filament [GO:0032982]		actin binding [GO:0003779]; structural constituent of cytoskeleton [GO:0005200]	
d2dlua1_d2he2b1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	axon cytoplasm [GO:1904115]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; guanylate kinase activity [GO:0004385]; kinase binding [GO:0019900]; structural constituent of postsynaptic density [GO:0098919]; anterograde axonal protein transport [GO:0099641]; cell-cell adhesion [GO:0098609]; cellular response to potassium ion [GO:0035865]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; MAPK cascade [GO:0000165]; negative regulation of phosphatase activity [GO:0010923]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of NMDA receptor activity [GO:2000310]; retrograde axonal protein transport [GO:0099642]; sensory perception of pain [GO:0019233]	bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	anterograde axonal protein transport [GO:0099641]; cell-cell adhesion [GO:0098609]; cellular response to potassium ion [GO:0035865]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; MAPK cascade [GO:0000165]; negative regulation of phosphatase activity [GO:0010923]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of NMDA receptor activity [GO:2000310]; retrograde axonal protein transport [GO:0099642]; sensory perception of pain [GO:0019233]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	axon cytoplasm [GO:1904115]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]		guanylate kinase activity [GO:0004385]; kinase binding [GO:0019900]; structural constituent of postsynaptic density [GO:0098919]
d2dlua1_d5fhta2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	CD40 receptor complex [GO:0035631]; chromatin [GO:0000785]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial intermembrane space [GO:0005758]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; serine-type endopeptidase complex [GO:1905370]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; unfolded protein binding [GO:0051082]; adult walking behavior [GO:0007628]; aging [GO:0007568]; cellular protein catabolic process [GO:0044257]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to interferon-beta [GO:0035458]; cellular response to oxidative stress [GO:0034599]; cellular response to retinoic acid [GO:0071300]; ceramide metabolic process [GO:0006672]; execution phase of apoptosis [GO:0097194]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitochondrion organization [GO:0007005]; negative regulation of cell cycle [GO:0045786]; negative regulation of mitophagy in response to mitochondrial depolarization [GO:1904924]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; neuron development [GO:0048666]; pentacyclic triterpenoid metabolic process [GO:0019742]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein autoprocessing [GO:0016540]; protein homotrimerization [GO:0070207]; proteolysis [GO:0006508]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of multicellular organism growth [GO:0040014]; response to herbicide [GO:0009635]	bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	adult walking behavior [GO:0007628]; aging [GO:0007568]; cellular protein catabolic process [GO:0044257]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to interferon-beta [GO:0035458]; cellular response to oxidative stress [GO:0034599]; cellular response to retinoic acid [GO:0071300]; ceramide metabolic process [GO:0006672]; execution phase of apoptosis [GO:0097194]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitochondrion organization [GO:0007005]; negative regulation of cell cycle [GO:0045786]; negative regulation of mitophagy in response to mitochondrial depolarization [GO:1904924]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; neuron development [GO:0048666]; pentacyclic triterpenoid metabolic process [GO:0019742]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein autoprocessing [GO:0016540]; protein homotrimerization [GO:0070207]; proteolysis [GO:0006508]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of multicellular organism growth [GO:0040014]; response to herbicide [GO:0009635]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	CD40 receptor complex [GO:0035631]; chromatin [GO:0000785]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial intermembrane space [GO:0005758]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; serine-type endopeptidase complex [GO:1905370]		identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; unfolded protein binding [GO:0051082]
d2dm0a1_d4ohla1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region DNA binding [GO:0001012]; activation of phospholipase C activity [GO:0007202]; adaptive immune response [GO:0002250]; cytokine production [GO:0001816]; peptidyl-tyrosine autophosphorylation [GO:0038083]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interferon-gamma-mediated signaling pathway [GO:0060335]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of transcription by RNA polymerase II [GO:0006357]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]; abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	activation of phospholipase C activity [GO:0007202]; adaptive immune response [GO:0002250]; cytokine production [GO:0001816]; peptidyl-tyrosine autophosphorylation [GO:0038083]; positive regulation of interferon-gamma-mediated signaling pathway [GO:0060335]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of transcription by RNA polymerase II [GO:0006357]; T cell receptor signaling pathway [GO:0050852]	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region DNA binding [GO:0001012]	cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]
d2dm4a1_d4lptd1__1	Metazoa		Chordata		cell [GO:0005623]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; multivesicular body [GO:0005771]; multivesicular body membrane [GO:0032585]; nuclear envelope lumen [GO:0005641]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; ADP-ribosylation factor binding [GO:0030306]; amyloid-beta binding [GO:0001540]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor activity [GO:0005041]; transmembrane signaling receptor activity [GO:0004888]; adaptive thermogenesis [GO:1990845]; cellular protein metabolic process [GO:0044267]; diet induced thermogenesis [GO:0002024]; insulin receptor recycling [GO:0038020]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of neurofibrillary tangle assembly [GO:1902997]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of triglyceride catabolic process [GO:0010897]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of choline O-acetyltransferase activity [GO:1902771]; positive regulation of early endosome to recycling endosome transport [GO:1902955]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of glial cell-derived neurotrophic factor secretion [GO:1900168]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to early endosome [GO:1902966]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to Golgi apparatus [GO:0034067]; protein maturation [GO:0051604]; protein retention in Golgi apparatus [GO:0045053]; protein targeting [GO:0006605]; protein targeting to lysosome [GO:0006622]; receptor-mediated endocytosis [GO:0006898]; regulation of smooth muscle cell migration [GO:0014910]		adaptive thermogenesis [GO:1990845]; cellular protein metabolic process [GO:0044267]; diet induced thermogenesis [GO:0002024]; insulin receptor recycling [GO:0038020]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of neurofibrillary tangle assembly [GO:1902997]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of triglyceride catabolic process [GO:0010897]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of choline O-acetyltransferase activity [GO:1902771]; positive regulation of early endosome to recycling endosome transport [GO:1902955]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of glial cell-derived neurotrophic factor secretion [GO:1900168]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to early endosome [GO:1902966]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to Golgi apparatus [GO:0034067]; protein maturation [GO:0051604]; protein retention in Golgi apparatus [GO:0045053]; protein targeting [GO:0006605]; protein targeting to lysosome [GO:0006622]; receptor-mediated endocytosis [GO:0006898]; regulation of smooth muscle cell migration [GO:0014910]		cell [GO:0005623]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; multivesicular body [GO:0005771]; multivesicular body membrane [GO:0032585]; nuclear envelope lumen [GO:0005641]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]		ADP-ribosylation factor binding [GO:0030306]; amyloid-beta binding [GO:0001540]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor activity [GO:0005041]; transmembrane signaling receptor activity [GO:0004888]	
d2dm5a__d5dg4d___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytosol [GO:0005829]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d2dm7a1_d2ajxl1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2dm7a1_d2uudj1__1	Metazoa		Chordata		cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]		G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]		cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]		ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	
d2dmra1_d1s3sa1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	periplasmic space [GO:0042597]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d2dmza1_d3dj3c___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]; activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]
d2dn2a__d3gysf___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2dn6a1_d1k5gk___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cytoplasm [GO:0005737]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; actin filament bundle assembly [GO:0051017]; isotype switching [GO:0045190]; negative regulation of actin filament depolymerization [GO:0030835]; negative regulation of cell-cell adhesion mediated by integrin [GO:0033633]; negative regulation of peptidyl-serine dephosphorylation [GO:1902309]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of mast cell chemotaxis [GO:0060754]; regulation of protein localization [GO:0032880]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	actin filament bundle assembly [GO:0051017]; isotype switching [GO:0045190]; negative regulation of actin filament depolymerization [GO:0030835]; negative regulation of cell-cell adhesion mediated by integrin [GO:0033633]; negative regulation of peptidyl-serine dephosphorylation [GO:1902309]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of mast cell chemotaxis [GO:0060754]; regulation of protein localization [GO:0032880]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cytoplasm [GO:0005737]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2dnea1_d2edga1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; identical protein binding [GO:0042802]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; pyruvate metabolic process [GO:0006090]; sleep [GO:0030431]; tricarboxylic acid cycle [GO:0006099]	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]; aminomethyltransferase activity [GO:0004047]; enzyme binding [GO:0019899]; glycine decarboxylation via glycine cleavage system [GO:0019464]; protein lipoylation [GO:0009249]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; pyruvate metabolic process [GO:0006090]; sleep [GO:0030431]; tricarboxylic acid cycle [GO:0006099]	glycine decarboxylation via glycine cleavage system [GO:0019464]; protein lipoylation [GO:0009249]	mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254]	glycine cleavage complex [GO:0005960]; mitochondrion [GO:0005739]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; identical protein binding [GO:0042802]	aminomethyltransferase activity [GO:0004047]; enzyme binding [GO:0019899]
d2dnka1_d5iqqd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; BRE binding [GO:0042835]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; alternative mRNA splicing, via spliceosome [GO:0000380]; embryo development ending in birth or egg hatching [GO:0009792]; germ cell development [GO:0007281]; in utero embryonic development [GO:0001701]; mRNA splice site selection [GO:0006376]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of retina development in camera-type eye [GO:1902866]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 14-3-3 protein binding [GO:0071889]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]; meiotic cell cycle [GO:0051321]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; snRNA catabolic process [GO:0016076]	alternative mRNA splicing, via spliceosome [GO:0000380]; embryo development ending in birth or egg hatching [GO:0009792]; germ cell development [GO:0007281]; in utero embryonic development [GO:0001701]; mRNA splice site selection [GO:0006376]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of retina development in camera-type eye [GO:1902866]	meiotic cell cycle [GO:0051321]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; snRNA catabolic process [GO:0016076]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	BRE binding [GO:0042835]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	14-3-3 protein binding [GO:0071889]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]
d2dnma1_d3hi9c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA binding [GO:0003723]; mRNA cis splicing, via spliceosome [GO:0045292]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	mRNA cis splicing, via spliceosome [GO:0045292]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]	RNA binding [GO:0003723]	AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d2dnoa1_d1cvjg2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; 7SK snRNA binding [GO:0097322]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; flagellated sperm motility [GO:0030317]; mRNA splice site selection [GO:0006376]; ncRNA transcription [GO:0098781]; nuclear body organization [GO:0030575]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	flagellated sperm motility [GO:0030317]; mRNA splice site selection [GO:0006376]; ncRNA transcription [GO:0098781]; nuclear body organization [GO:0030575]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	7SK snRNA binding [GO:0097322]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]
d2dnwa1_d5h9ga1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; calcium ion binding [GO:0005509]; fatty acid binding [GO:0005504]; NADH dehydrogenase (ubiquinone) activity [GO:0008137]; fatty acid biosynthetic process [GO:0006633]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; protein lipoylation [GO:0009249]	cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]; phosphopantetheine binding [GO:0031177]	fatty acid biosynthetic process [GO:0006633]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; protein lipoylation [GO:0009249]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; calcium ion binding [GO:0005509]; fatty acid binding [GO:0005504]; NADH dehydrogenase (ubiquinone) activity [GO:0008137]	acyl carrier activity [GO:0000036]; phosphopantetheine binding [GO:0031177]
d2doca1_d3qhtc___1	Metazoa	Fungi	Chordata	Ascomycota	axon [GO:0030424]; integral component of membrane [GO:0016021]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; axonal fasciculation [GO:0007413]; neuron cell-cell adhesion [GO:0007158]; sensory perception of smell [GO:0007608]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]; identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]; protein sumoylation [GO:0016925]	axonal fasciculation [GO:0007413]; neuron cell-cell adhesion [GO:0007158]; sensory perception of smell [GO:0007608]	protein sumoylation [GO:0016925]	axon [GO:0030424]; integral component of membrane [GO:0016021]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]	identical protein binding [GO:0042802]	identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]
d2doob__d4zo2a___1			Proteobacteria	Bacteroidetes	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	carboxylic ester hydrolase activity [GO:0052689]; metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	carboxylic ester hydrolase activity [GO:0052689]; metal ion binding [GO:0046872]
d2dp5a1_d4hizc2__1			Firmicutes		hyalurononglucosaminidase activity [GO:0004415]; capsule polysaccharide biosynthetic process [GO:0045227]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	capsule polysaccharide biosynthetic process [GO:0045227]	metabolic process [GO:0008152]			hyalurononglucosaminidase activity [GO:0004415]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; metal ion binding [GO:0046872]
d2dpfa__d1kj1d___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d2dpfb__d1bwua___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d2dpfc__d4h3ob___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d2dpfd__d2d04e___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d2dpla2_d1gpma3__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; pyrophosphatase activity [GO:0016462]	cytosol [GO:0005829]; ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; GMP synthase activity [GO:0003921]; identical protein binding [GO:0042802]; pyrophosphatase activity [GO:0016462]; glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]		glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]		cytosol [GO:0005829]	ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; pyrophosphatase activity [GO:0016462]	ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; GMP synthase activity [GO:0003921]; identical protein binding [GO:0042802]; pyrophosphatase activity [GO:0016462]
d2dpza__d2qogc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; envenomation resulting in induction of edema in other organism [GO:0044398]; envenomation resulting in modulation of apoptotic process in other organism [GO:0044534]; envenomation resulting in muscle damage in other organism [GO:0044521]; envenomation resulting in positive regulation of platelet aggregation in other organism [GO:0044478]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; envenomation resulting in induction of edema in other organism [GO:0044398]; envenomation resulting in modulation of apoptotic process in other organism [GO:0044534]; envenomation resulting in muscle damage in other organism [GO:0044521]; envenomation resulting in positive regulation of platelet aggregation in other organism [GO:0044478]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d2dqch1_d5vshl1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d2dqcl__d4ywgm2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	structural molecule activity [GO:0005198]
d2dqdh1_d2gj6d1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2dqdy__d155la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2dqeh1_d1rvfl___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2dqeh1_d3jwdc2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d2dqel__d3bd3a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d2dqel__d3tjel2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	CD95 death-inducing signaling complex [GO:0031265]; cell surface [GO:0009986]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to amino acid starvation [GO:0034198]; cellular response to hyperoxia [GO:0071455]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway [GO:0097191]; Fas signaling pathway [GO:0036337]; immune response [GO:0006955]; necroptotic signaling pathway [GO:0097527]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of protein phosphorylation [GO:0001934]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of stress-activated MAPK cascade [GO:0032872]; signal transduction [GO:0007165]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to amino acid starvation [GO:0034198]; cellular response to hyperoxia [GO:0071455]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway [GO:0097191]; Fas signaling pathway [GO:0036337]; immune response [GO:0006955]; necroptotic signaling pathway [GO:0097527]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of protein phosphorylation [GO:0001934]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of stress-activated MAPK cascade [GO:0032872]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	CD95 death-inducing signaling complex [GO:0031265]; cell surface [GO:0009986]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]
d2dqey__d1qt6a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2dqfb1_d4h25d2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d2dqfc__d174la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2dqfe__d5nhwl1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d2dqff__d1l42a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2dqgy__d1wvua___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]
d2dqhy__d1lspa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2dqih__d4jaml1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d2dqjh__d1ic1b2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]
d2dqka__d4omde1__1	Fungi	Metazoa	Ascomycota	Chordata	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d2dqna__d3qj8a1__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]; regulation of translational fidelity [GO:0006450]; translation [GO:0006412]	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]	regulation of translational fidelity [GO:0006450]; translation [GO:0006412]	fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]	ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]	acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]
d2dqtl2_d4kzdl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2dqul1_d2cjvj___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2dqul2_d1cd0a___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]
d2dqyb__d1xzga___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	cutinase activity [GO:0050525]
d2dqzb__d3ailc___1	Metazoa		Chordata	Crenarchaeota	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]		carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]
d2dqzc__d2i03c2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2dr0c1_d2bgnd2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2dr5a2_d1knyb2__1			Euryarchaeota	Firmicutes	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	nucleotidyltransferase activity [GO:0016779]; response to antibiotic [GO:0046677]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	response to antibiotic [GO:0046677]			ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	nucleotidyltransferase activity [GO:0016779]
d2dr7a1_d4lt6b2__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]		cytosol [GO:0005829]; membrane [GO:0016020]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d2drcb__d4m2xa___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]
d2dria__d1abfa___1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; monosaccharide binding [GO:0048029]; D-ribose transmembrane transport [GO:0015752]; positive chemotaxis [GO:0050918]	outer membrane-bounded periplasmic space [GO:0030288]; ATPase-coupled monosaccharide transmembrane transporter activity [GO:0015407]; monosaccharide binding [GO:0048029]; L-arabinose transmembrane transport [GO:0042882]	D-ribose transmembrane transport [GO:0015752]; positive chemotaxis [GO:0050918]	L-arabinose transmembrane transport [GO:0042882]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]	monosaccharide binding [GO:0048029]	ATPase-coupled monosaccharide transmembrane transporter activity [GO:0015407]; monosaccharide binding [GO:0048029]
d2droa__d2zzra___1			Firmicutes		oligosaccharide reducing-end xylanase activity [GO:0033951]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]				oligosaccharide reducing-end xylanase activity [GO:0033951]	
d2drra__d3glya___1		Fungi	Firmicutes	Ascomycota	oligosaccharide reducing-end xylanase activity [GO:0033951]; xylan catabolic process [GO:0045493]	glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			oligosaccharide reducing-end xylanase activity [GO:0033951]	glucan 1,4-alpha-glucosidase activity [GO:0004339]; starch binding [GO:2001070]
d2dryb__d2z48b2__1	Metazoa	Metazoa	Annelida	Echinodermata	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2ds0b__d2d20b2__1	Metazoa		Annelida	Actinobacteria	carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]
d2ds0b__d3ah2a1__1	Metazoa		Annelida		carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d2ds4a1_d1clca2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleoplasm [GO:0005654]; zinc ion binding [GO:0008270]; bone development [GO:0060348]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	bone development [GO:0060348]	cellulose catabolic process [GO:0030245]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleoplasm [GO:0005654]		zinc ion binding [GO:0008270]	cellulase activity [GO:0008810]
d2ds4a1_d2wqwa2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleoplasm [GO:0005654]; zinc ion binding [GO:0008270]; bone development [GO:0060348]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	bone development [GO:0060348]	pathogenesis [GO:0009405]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	zinc ion binding [GO:0008270]	heparin binding [GO:0008201]; lipid binding [GO:0008289]
d2dsaa1_d2fwea2__1			Proteobacteria	Proteobacteria	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]; electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]		cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]		cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]	glutathione transferase activity [GO:0004364]	electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2dsab1_d4hj2b1__1		Metazoa	Proteobacteria	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione transferase activity [GO:0004364]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2dsac2_d5a4ue2__1		Viridiplantae	Proteobacteria	Streptophyta	glutathione transferase activity [GO:0004364]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	glutathione transferase activity [GO:0004364]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d2dsac2_d5agya2__1		Viridiplantae	Proteobacteria	Streptophyta	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]		glutathione metabolic process [GO:0006749]		cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2dsad1_d1gsfa2__1		Metazoa	Proteobacteria	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione transferase activity [GO:0004364]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2dsna__d4x7ba1__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]					metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d2dsnb__d4w63a___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]		acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	acetylcholinesterase activity [GO:0003990]
d2dsob2_d5gx1a___1		Metazoa	Firmicutes	Arthropoda	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]			cytoplasm [GO:0005737]		hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2dsod__d5d9da___1		Metazoa	Firmicutes	Arthropoda	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]			cytoplasm [GO:0005737]		hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2dsoe2_d5gtqa___1		Metazoa	Firmicutes	Arthropoda	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]			cytoplasm [GO:0005737]		hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2dsta1_d2dstb___1			Deinococcus-Thermus	Deinococcus-Thermus								
d2dsta1_d3t4ud___1			Deinococcus-Thermus	Proteobacteria		arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]						arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]
d2dt2a2_d1eiba3__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cellular response to tumor necrosis factor [GO:0071356]; inflammatory response [GO:0006954]; interleukin-8 secretion [GO:0072606]; lung development [GO:0030324]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; response to interleukin-1 [GO:0070555]; response to interleukin-6 [GO:0070741]; response to mechanical stimulus [GO:0009612]; response to tumor necrosis factor [GO:0034612]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]		carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d2dtdb1_d1evya2__1			Euryarchaeota		nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycosome [GO:0020015]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]		carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]		glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycosome [GO:0020015]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]
d2dtga1_d1epfa1__1		Metazoa		Chordata		glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]		aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]		glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]		cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]
d2dtgb2_d1mwad1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2dtgd1_d4p2ch___1				Proteobacteria		extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]		hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]		extracellular region [GO:0005576]		
d2dtge4_d5wk4a___1												
d2dthb2_d4p3pb1__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cellular protein modification process [GO:0006464]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2dtia2_d3p8ya___1			Euryarchaeota	Euryarchaeota	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; tRNA aminoacylation for protein translation [GO:0006418]	cellular protein modification process [GO:0006464]	tRNA aminoacylation for protein translation [GO:0006418]			ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]
d2dtml1_d4ma1l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2dtml2_d5ocal1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor recycling [GO:0001920]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of receptor recycling [GO:0001920]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]
d2dtqa3_d3muge2__1												
d2dtsa2_d1osph2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2dtsb1_d5v7rl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2dtua1_d3dlga2__1					3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2dtwb__d1cjpc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2dtwb__d3m3cb1__1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	carbohydrate binding [GO:0030246]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]		apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			carbohydrate binding [GO:0030246]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d2dtxb1_d1qyca___1		Viridiplantae	Euryarchaeota	Streptophyta	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor [GO:0050664]; lignan biosynthetic process [GO:0009807]		lignan biosynthetic process [GO:0009807]			nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor [GO:0050664]
d2du0b__d1v6jc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2du0b__d3mw4a1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	GABA-ergic synapse [GO:0098982]; integral component of membrane [GO:0016021]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; calcium channel regulator activity [GO:0005246]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle exocytosis [GO:2000300]; synapse assembly [GO:0007416]		cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle exocytosis [GO:2000300]; synapse assembly [GO:0007416]		GABA-ergic synapse [GO:0098982]; integral component of membrane [GO:0016021]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]	carbohydrate binding [GO:0030246]	calcium channel regulator activity [GO:0005246]; metal ion binding [GO:0046872]
d2du0c__d3t1la___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d2du0d__d4atfb___1	Viridiplantae		Streptophyta	Bacteroidetes	carbohydrate binding [GO:0030246]	cell outer membrane [GO:0009279]; beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		cell outer membrane [GO:0009279]	carbohydrate binding [GO:0030246]	beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]
d2du1d__d3rsja1__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; membrane [GO:0016020]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; membrane [GO:0016020]	carbohydrate binding [GO:0030246]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d2du2d__d1vypx___1			Firmicutes	Proteobacteria	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d2du2d__d5cpla___1			Firmicutes	Proteobacteria	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2dv7a__d2ejja___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2dv9a__d4ym0a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]		cell adhesion [GO:0007155]		collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2dv9c__d2ymza1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2dvac__d4no4f___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of viral entry into host cell [GO:0046598]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of viral entry into host cell [GO:0046598]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]
d2dvba__d2gdfb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2dvba__d2zgpb___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]		apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d2dvbc__d4yw2b1__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d2dvdd__d4yz4a1__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d2dvea1_d2alyb6__1			Euryarchaeota	Deinococcus-Thermus	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	cellular protein modification process [GO:0006464]	phenylalanyl-tRNA aminoacylation [GO:0006432]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]
d2dvfa__d2e7td___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d2dvfc__d2a6xa1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]		endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; protein transport [GO:0015031]		COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2dvfd__d1qdca___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2dvgb__d3afkb1__1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]		apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d2dvgc__d3b9cb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; intracellular [GO:0005622]; carbohydrate binding [GO:0030246]				cytoplasm [GO:0005737]; intracellular [GO:0005622]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d2dvgd__d2nn8a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d2dvia2_d9icha4__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d2dvlb2_d2cx9a1__1			Deinococcus-Thermus	Deinococcus-Thermus	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]					acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d2dvpa__d3s86b___1			Euryarchaeota	Thermotogae	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]
d2dvta1_d4eria___1			Proteobacteria	Proteobacteria	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]					carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2dvva1_d4tu4a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; chromatin organization [GO:0006325]; negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	chromatin organization [GO:0006325]; negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; histone binding [GO:0042393]
d2dvwa__d3twua___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome regulatory particle, base subcomplex [GO:0008540]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription factor binding [GO:0008134]; apoptotic process [GO:0006915]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; proteasome regulatory particle assembly [GO:0070682]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	apoptotic process [GO:0006915]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; proteasome regulatory particle assembly [GO:0070682]; regulation of transcription by RNA polymerase II [GO:0006357]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome regulatory particle, base subcomplex [GO:0008540]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; transcription factor binding [GO:0008134]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]
d2dw6b1_d2ox4g2__1			Proteobacteria	Proteobacteria	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	metal ion binding [GO:0046872]	protein homooligomerization [GO:0051260]				D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]
d2dw6c1_d3twbb2__1			Proteobacteria	Proteobacteria	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	protein homooligomerization [GO:0051260]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]
d2dw6c2_d3ttea1__1			Proteobacteria	Proteobacteria	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]	protein homooligomerization [GO:0051260]	cellular amino acid catabolic process [GO:0009063]			D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]
d2dw6c2_d4e6mh1__1			Proteobacteria	Proteobacteria	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	metal ion binding [GO:0046872]	protein homooligomerization [GO:0051260]				D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]
d2dw6d1_d3ujfb2__1		Metazoa	Proteobacteria	Chordata	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	protein homooligomerization [GO:0051260]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2dw6d1_d4e6me2__1			Proteobacteria	Proteobacteria	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	metal ion binding [GO:0046872]	protein homooligomerization [GO:0051260]				D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]
d2dw7a2_d3pwib1__1			Proteobacteria	Proteobacteria	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	protein homooligomerization [GO:0051260]	D-glucarate catabolic process [GO:0042838]			D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d2dw7b1_d3qtpa2__1			Proteobacteria		D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	protein homooligomerization [GO:0051260]	glycolytic process [GO:0006096]		phosphopyruvate hydratase complex [GO:0000015]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2dw7b2_d3desb1__1			Proteobacteria	Thermotogae	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	protein homooligomerization [GO:0051260]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]			D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d2dw7d1_d1jpma1__1			Proteobacteria	Firmicutes	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	protein homooligomerization [GO:0051260]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]			D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d2dw7f1_d4e6ma2__1			Proteobacteria	Proteobacteria	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	metal ion binding [GO:0046872]	protein homooligomerization [GO:0051260]				D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]
d2dw7h1_d3ucdb2__1		Metazoa	Proteobacteria	Chordata	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	protein homooligomerization [GO:0051260]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2dw7i1_d1mraa1__1			Proteobacteria	Proteobacteria	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	protein homooligomerization [GO:0051260]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]			D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d2dw7i2_d4ihcc1__1			Proteobacteria	Proteobacteria	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	protein homooligomerization [GO:0051260]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d2dw7m2_d1nela2__1		Fungi	Proteobacteria	Ascomycota	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	protein homooligomerization [GO:0051260]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2dw7m2_d4e4fd1__1			Proteobacteria	Proteobacteria	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	protein homooligomerization [GO:0051260]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d2dw7o1_d3toyd2__1			Proteobacteria	Proteobacteria	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]	protein homooligomerization [GO:0051260]	cellular amino acid catabolic process [GO:0009063]			D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]
d2dw7p2_d3qkff1__1			Proteobacteria		D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]		protein homooligomerization [GO:0051260]				D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]	
d2dwda1_d3wn5f2__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	voltage-gated potassium channel complex [GO:0008076]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	IgG binding [GO:0019864]
d2dwda2_d4x7tb1__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2dwdb1_d2ddql1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2dwea1_d5f8rd1__1			Actinobacteria	Proteobacteria	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2dwea2_d5vqmc1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2dweb2_d3auvc2__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2dwqa2_d5ee1a2__1		Viridiplantae	Deinococcus-Thermus	Streptophyta	ATP binding [GO:0005524]; ATPase activity [GO:0016887]; GTP binding [GO:0005525]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of response to salt stress [GO:1901001]; response to cadmium ion [GO:0046686]; response to salt stress [GO:0009651]		negative regulation of defense response to bacterium [GO:1900425]; negative regulation of response to salt stress [GO:1901001]; response to cadmium ion [GO:0046686]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]
d2dwqb2_d1tkea1__1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; ATPase activity [GO:0016887]; GTP binding [GO:0005525]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]		negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2dwra__d2vh9b___1		Viridiplantae		Streptophyta	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; receptor-mediated virion attachment to host cell [GO:0046813]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	apoplast [GO:0048046]; cell wall [GO:0005618]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]; cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; receptor-mediated virion attachment to host cell [GO:0046813]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	apoplast [GO:0048046]; cell wall [GO:0005618]		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]
d2dwsa1_d1j9qc1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2dwsa1_d2j57c___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2dwta1_d1tefa___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2dwta1_d2dwta2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2dwta2_d2occb1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2dwxa__d1ky6a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]
d2dwxc__d4bcxa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	AP-1 adaptor complex [GO:0030121]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle [GO:0005798]; membrane [GO:0016020]; transport vesicle [GO:0030133]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	AP-1 adaptor complex [GO:0030121]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; transport vesicle [GO:0030133]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	
d2dwxd__d1iu1a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; recycling endosome [GO:0055037]; trans-Golgi network membrane [GO:0032588]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; Rab GTPase binding [GO:0017137]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; regulation of defense response to virus by virus [GO:0050690]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; regulation of defense response to virus by virus [GO:0050690]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; recycling endosome [GO:0055037]; trans-Golgi network membrane [GO:0032588]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; Rab GTPase binding [GO:0017137]
d2dwxd__d2iv8a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	AP-2 adaptor complex [GO:0030122]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]; clathrin binding [GO:0030276]; protein-containing complex binding [GO:0044877]; signal sequence binding [GO:0005048]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; coronary vasculature development [GO:0060976]; ephrin receptor signaling pathway [GO:0048013]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; membrane organization [GO:0061024]; negative regulation of neuron death [GO:1901215]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein localization to membrane [GO:1905477]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; regulation of defense response to virus by virus [GO:0050690]; synaptic vesicle endocytosis [GO:0048488]; ventricular septum development [GO:0003281]; vesicle-mediated transport [GO:0016192]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; coronary vasculature development [GO:0060976]; ephrin receptor signaling pathway [GO:0048013]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; membrane organization [GO:0061024]; negative regulation of neuron death [GO:1901215]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein localization to membrane [GO:1905477]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; regulation of defense response to virus by virus [GO:0050690]; synaptic vesicle endocytosis [GO:0048488]; ventricular septum development [GO:0003281]; vesicle-mediated transport [GO:0016192]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	AP-2 adaptor complex [GO:0030122]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	clathrin binding [GO:0030276]; protein-containing complex binding [GO:0044877]; signal sequence binding [GO:0005048]
d2dwya__d1kyfa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]
d2dwyb__d1gyua1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]; collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; microtubule cytoskeleton [GO:0015630]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; trans-Golgi network [GO:0005802]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	collagen binding [GO:0005518]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; protein C-terminus binding [GO:0008022]; Rab GTPase binding [GO:0017137]
d2dwyb__d2vj0a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]
d2dwyd__d1kyua1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; regulation of hematopoietic stem cell differentiation [GO:1902036]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	AP-2 adaptor complex [GO:0030122]; cytoplasmic vesicle [GO:0031410]; membrane coat [GO:0030117]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	clathrin adaptor activity [GO:0035615]; disordered domain specific binding [GO:0097718]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]
d2dx5b1_d1kota1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; synapse [GO:0045202]; beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; chemical synaptic transmission [GO:0007268]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein targeting [GO:0006605]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; chemical synaptic transmission [GO:0007268]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein targeting [GO:0006605]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; synapse [GO:0045202]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d2dx7a2_d5hqta1__1			Euryarchaeota	Proteobacteria	aspartate racemase activity [GO:0047689]; nitrogen compound metabolic process [GO:0006807]	aspartate racemase activity [GO:0047689]; glutamate racemase activity [GO:0008881]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			aspartate racemase activity [GO:0047689]	aspartate racemase activity [GO:0047689]; glutamate racemase activity [GO:0008881]
d2dxda__d4s0ma___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2dxea__d3pj9d1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2dxeb__d3ngti___1			Euryarchaeota		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d2dxib1_d5h4vf2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	glutamyl-tRNA aminoacylation [GO:0006424]	glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2dxib2_d3otwc___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	glutamyl-tRNA aminoacylation [GO:0006424]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d2dxla1_d2o8ab___1		Metazoa	Proteobacteria	Chordata	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; protein domain specific binding [GO:0019904]; protein phosphatase inhibitor activity [GO:0004864]; glycogen metabolic process [GO:0005977]; negative regulation of protein binding [GO:0032091]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of signal transduction [GO:0009966]		glycogen metabolic process [GO:0005977]; negative regulation of protein binding [GO:0032091]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of signal transduction [GO:0009966]		cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; growth cone [GO:0030426]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	protein domain specific binding [GO:0019904]; protein phosphatase inhibitor activity [GO:0004864]
d2dxlb__d3h66a___1		Metazoa	Proteobacteria	Chordata	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]
d2dxma__d1y7db___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2dxmc__d5v3ub___1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen transport [GO:0015671]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxygen transport [GO:0015671]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d2dxta1_d2deqa1__1			Euryarchaeota	Euryarchaeota	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	cellular protein modification process [GO:0006464]	cellular protein modification process [GO:0006464]			ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d2dxub1_d1yfrb2__1			Euryarchaeota	Aquificae	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	cytosol [GO:0005829]; alanine-tRNA ligase activity [GO:0004813]; amino acid binding [GO:0016597]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; alanyl-tRNA aminoacylation [GO:0006419]; tRNA modification [GO:0006400]	cellular protein modification process [GO:0006464]	alanyl-tRNA aminoacylation [GO:0006419]; tRNA modification [GO:0006400]		cytosol [GO:0005829]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]	alanine-tRNA ligase activity [GO:0004813]; amino acid binding [GO:0016597]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2dxwb__d2huva___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2dxxb__d2pb5b___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2dy1a3_d2br2h1__1			Deinococcus-Thermus	Crenarchaeota	GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]		rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	3'-5'-exoribonuclease activity [GO:0000175]
d2dy1a5_d2bm0a4__1			Deinococcus-Thermus	Deinococcus-Thermus	GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]		translational elongation [GO:0006414]		cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]
d2dy2a2_d5ue6b1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2dyab__d4cp5c___1			Euryarchaeota		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2dyab__d5u2ib1__1			Euryarchaeota	Heterolobosea	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d2dynb__d4zrka3__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendritic spine [GO:0043197]; dendritic spine head [GO:0044327]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane coat [GO:0030117]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic endocytic zone membrane [GO:0098844]; postsynaptic membrane [GO:0045211]; presynaptic endocytic zone membrane [GO:0098835]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; varicosity [GO:0043196]; D2 dopamine receptor binding [GO:0031749]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; endocytosis [GO:0006897]; endosome organization [GO:0007032]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled receptor internalization [GO:0002031]; mitochondrial fission [GO:0000266]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synapse structure or activity [GO:0050803]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; toxin transport [GO:1901998]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	endocytosis [GO:0006897]; endosome organization [GO:0007032]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled receptor internalization [GO:0002031]; mitochondrial fission [GO:0000266]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synapse structure or activity [GO:0050803]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; toxin transport [GO:1901998]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendritic spine [GO:0043197]; dendritic spine head [GO:0044327]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane coat [GO:0030117]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic endocytic zone membrane [GO:0098844]; postsynaptic membrane [GO:0045211]; presynaptic endocytic zone membrane [GO:0098835]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; varicosity [GO:0043196]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	D2 dopamine receptor binding [GO:0031749]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d2dypa1_d4s1ql2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2dypa2_d1i3rg2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2dypa2_d4p5ka1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d2dypb2_d3kymi1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2dypd1_d5jiib2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2dyrb1_d3uada2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	ATP synthesis coupled electron transport [GO:0042773]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d2dz9b1_d6aqga2__1			Euryarchaeota	Actinobacteria	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	cellular protein modification process [GO:0006464]	lysyl-tRNA aminoacylation [GO:0006430]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d2dzda2_d2fb9a2__1			Firmicutes	Deinococcus-Thermus	ATP binding [GO:0005524]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]		cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2dzda2_d2nu9b2__1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]		nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d2dzdb1_d3tina1__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; metal ion binding [GO:0046872]	nucleotide binding [GO:0000166]; cellular protein modification process [GO:0006464]		cellular protein modification process [GO:0006464]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]	nucleotide binding [GO:0000166]
d2dzea__d1roca1__1	Fungi	Fungi	Ascomycota	Ascomycota	mating-type region heterochromatin [GO:0031934]; nuclear nucleosome [GO:0000788]; nuclear pericentric heterochromatin [GO:0031618]; nuclear subtelomeric heterochromatin [GO:1990707]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; cellular response to DNA damage stimulus [GO:0006974]; nucleosome assembly [GO:0006334]; regulation of extent of heterochromatin assembly [GO:0031454]	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleus [GO:0005634]; histone binding [GO:0042393]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H2B ubiquitination [GO:0033523]; nucleosome disassembly [GO:0006337]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of gene expression [GO:0010468]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]	cellular response to DNA damage stimulus [GO:0006974]; nucleosome assembly [GO:0006334]; regulation of extent of heterochromatin assembly [GO:0031454]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H2B ubiquitination [GO:0033523]; nucleosome disassembly [GO:0006337]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of gene expression [GO:0010468]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]	mating-type region heterochromatin [GO:0031934]; nuclear nucleosome [GO:0000788]; nuclear pericentric heterochromatin [GO:0031618]; nuclear subtelomeric heterochromatin [GO:1990707]; nucleus [GO:0005634]	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	histone binding [GO:0042393]
d2dzoc__d4hb5a___1	Fungi		Ascomycota		cytosol [GO:0005829]; nucleus [GO:0005634]; proteasome regulatory particle binding [GO:1904855]; proteasome regulatory particle assembly [GO:0070682]		proteasome regulatory particle assembly [GO:0070682]		cytosol [GO:0005829]; nucleus [GO:0005634]		proteasome regulatory particle binding [GO:1904855]	
d2dzqa1_d2dn4a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription by RNA polymerase II [GO:0006366]; transition between slow and fast fiber [GO:0014886]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription by RNA polymerase II [GO:0006366]; transition between slow and fast fiber [GO:0014886]	negative regulation of angiogenesis [GO:0016525]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2dzra1_d2dn5a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription by RNA polymerase II [GO:0006366]; transition between slow and fast fiber [GO:0014886]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription by RNA polymerase II [GO:0006366]; transition between slow and fast fiber [GO:0014886]	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription by RNA polymerase II [GO:0006366]; transition between slow and fast fiber [GO:0014886]	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription by RNA polymerase II [GO:0006366]; transition between slow and fast fiber [GO:0014886]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]
d2dzra1_d2ed2a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription by RNA polymerase II [GO:0006366]; transition between slow and fast fiber [GO:0014886]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription by RNA polymerase II [GO:0006366]; transition between slow and fast fiber [GO:0014886]	negative regulation of angiogenesis [GO:0016525]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2e07a__d2e16b___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2e0ma__d5m9md___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	RNA phosphodiester bond hydrolysis [GO:0090501]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular exosome [GO:0070062]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]
d2e0mb__d2e0ja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular exosome [GO:0070062]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	RNA phosphodiester bond hydrolysis [GO:0090501]	RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular exosome [GO:0070062]	extracellular exosome [GO:0070062]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]
d2e0qa__d2vl3b___1		Metazoa	Crenarchaeota	Chordata	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	protein disulfide oxidoreductase activity [GO:0015035]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]
d2e11b__d2fkud___1			Proteobacteria		2-oxoglutaramate amidase activity [GO:0106008]; omega-amidase activity [GO:0050152]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				2-oxoglutaramate amidase activity [GO:0106008]; omega-amidase activity [GO:0050152]	
d2e11c__d2fkua___1			Proteobacteria		2-oxoglutaramate amidase activity [GO:0106008]; omega-amidase activity [GO:0050152]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				2-oxoglutaramate amidase activity [GO:0106008]; omega-amidase activity [GO:0050152]	
d2e18b__d1j1zc1__1			Euryarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; double-stranded DNA binding [GO:0003690]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]; DNA topological change [GO:0006265]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]	DNA topological change [GO:0006265]; NAD biosynthetic process [GO:0009435]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; double-stranded DNA binding [GO:0003690]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]	argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]
d2e1ba1_d1skqa1__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; alanine-tRNA ligase activity [GO:0004813]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; alanyl-tRNA aminoacylation [GO:0006419]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	alanyl-tRNA aminoacylation [GO:0006419]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	alanine-tRNA ligase activity [GO:0004813]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2e1db__d1hfbg___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; carbohydrate binding [GO:0030246]; monosaccharide binding [GO:0048029]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glyceraldehyde-3-phosphate metabolic process [GO:0019682]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glyceraldehyde-3-phosphate metabolic process [GO:0019682]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; monosaccharide binding [GO:0048029]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]
d2e1ra4_d1ktva4__1	Fungi		Ascomycota	Deinococcus-Thermus	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]	maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	translational elongation [GO:0006414]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]	GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]
d2e1ta1_d2bgha1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	vinorine synthase activity [GO:0050636]; alkaloid metabolic process [GO:0009820]		alkaloid metabolic process [GO:0009820]			transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	vinorine synthase activity [GO:0050636]
d2e1ta1_d2ii4b___1	Viridiplantae	Metazoa	Streptophyta	Chordata	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]				cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d2e1wa__d2bb0b2__1	Metazoa		Chordata	Firmicutes	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]; adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	cytoplasm [GO:0005737]; imidazolonepropionase activity [GO:0050480]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]; histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]	adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]	cytoplasm [GO:0005737]	adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]	imidazolonepropionase activity [GO:0050480]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]
d2e27l__d1a3rl2__1						host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2e27l__d3nh7l1__1		Metazoa		Chordata		dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]		BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; dorsal aorta morphogenesis [GO:0035912]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]		dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]
d2e2da__d2o36a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; peptide binding [GO:0042277]; peptide metabolic process [GO:0006518]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	peptide metabolic process [GO:0006518]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; peptide binding [GO:0042277]
d2e2jc2_d1smyk2__1	Fungi		Ascomycota	Deinococcus-Thermus	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]	transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]		DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d2e2ra__d5k3lc___1	Metazoa	Metazoa	Chordata	Chordata	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; AF-2 domain binding [GO:0050682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid receptor signaling pathway [GO:0048384]; transcription initiation from RNA polymerase II promoter [GO:0006367]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid receptor signaling pathway [GO:0048384]; transcription initiation from RNA polymerase II promoter [GO:0006367]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	AF-2 domain binding [GO:0050682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d2e2ta2_d1spua2__1			Actinobacteria	Proteobacteria	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	periplasmic space [GO:0042597]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]		periplasmic space [GO:0042597]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d2e36a2_d2zjqf2__1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	cytosolic large ribosomal subunit [GO:0022625]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2e3ha1_d1whka1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; intermediate filament [GO:0005882]; kinetochore [GO:0000776]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nuclear envelope [GO:0005635]; ruffle [GO:0001726]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116]; protein transport into plasma membrane raft [GO:0044861]	intracellular membrane-bounded organelle [GO:0043231]	microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116]; protein transport into plasma membrane raft [GO:0044861]		centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; intermediate filament [GO:0005882]; kinetochore [GO:0000776]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nuclear envelope [GO:0005635]; ruffle [GO:0001726]	intracellular membrane-bounded organelle [GO:0043231]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270]	
d2e3za__d1xh2a2__1	Fungi	Metazoa	Basidiomycota	Chordata	beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cellulose catabolic process [GO:0030245]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; scopolin beta-glucosidase activity [GO:0102483]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d2e3zb__d1jyxb5__1	Fungi		Basidiomycota	Proteobacteria	beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; scopolin beta-glucosidase activity [GO:0102483]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2e40a__d1e43a2__1	Fungi		Basidiomycota	Firmicutes	beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; scopolin beta-glucosidase activity [GO:0102483]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d2e40b__d1j0zc2__1	Fungi		Basidiomycota	Firmicutes	beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]			beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; scopolin beta-glucosidase activity [GO:0102483]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2e4ja1_d1fema___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; response to glucocorticoid [GO:0051384]	extracellular space [GO:0005615]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; response to glucocorticoid [GO:0051384]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	extracellular space [GO:0005615]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]	retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]
d2e4mb1_d4qd2d1__1		Metazoa		Chordata	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	pathogenesis [GO:0009405]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]		alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d2e4pa__d1ww9a1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	aromatic compound catabolic process [GO:0019439]				2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2e4pa__d3l70e2__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	aromatic compound catabolic process [GO:0019439]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d2e4pb__d4aayd___1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]	aromatic compound catabolic process [GO:0019439]				2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]
d2e51a__d3l2ys___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d2e53d__d2cy6a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2e53d__d4r9da___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d2e5fa__d1u0eb1__1		Metazoa	Euryarchaeota	Chordata	carbohydrate derivative binding [GO:0097367]; carbohydrate derivative metabolic process [GO:1901135]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate derivative metabolic process [GO:1901135]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]		ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	carbohydrate derivative binding [GO:0097367]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d2e5fb__d1tzba___1			Euryarchaeota	Crenarchaeota	carbohydrate derivative binding [GO:0097367]; carbohydrate derivative metabolic process [GO:1901135]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]; carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	carbohydrate derivative metabolic process [GO:1901135]	carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]			carbohydrate derivative binding [GO:0097367]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]
d2e5lc2_d1vs5c2__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d2e5lq1_d4h02e1__1			Deinococcus-Thermus	Apicomplexa	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytosol [GO:0005829]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; tRNA binding [GO:0000049]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; lysyl-tRNA aminoacylation [GO:0006430]	translation [GO:0006412]	diadenosine tetraphosphate biosynthetic process [GO:0015966]; lysyl-tRNA aminoacylation [GO:0006430]	ribosome [GO:0005840]	cytosol [GO:0005829]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; tRNA binding [GO:0000049]
d2e5lt1_d1n34t___1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2e5wc__d4gf5s___1			Euryarchaeota	Actinobacteria	cytoplasm [GO:0005737]; spermidine synthase activity [GO:0004766]; spermidine biosynthetic process [GO:0008295]	O-methyltransferase activity [GO:0008171]	spermidine biosynthetic process [GO:0008295]		cytoplasm [GO:0005737]		spermidine synthase activity [GO:0004766]	O-methyltransferase activity [GO:0008171]
d2e64b2_d1adyd2__1			Euryarchaeota	Deinococcus-Thermus	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	cellular protein modification process [GO:0006464]	histidyl-tRNA aminoacylation [GO:0006427]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]
d2e66b__d4e98a___1			Euryarchaeota	Apicomplexa	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; response to metal ion [GO:0010038]	response to metal ion [GO:0010038]	response to metal ion [GO:0010038]	response to metal ion [GO:0010038]	cytoplasm [GO:0005737]		metal ion binding [GO:0046872]	
d2e66c__d3x3ub___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; metal ion binding [GO:0046872]; protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	response to metal ion [GO:0010038]	protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; metal ion binding [GO:0046872]
d2e6db__d3gr7a___1				Firmicutes	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; NADP binding [GO:0050661]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]; response to toxic substance [GO:0009636]	'de novo' UMP biosynthetic process [GO:0044205]	response to toxic substance [GO:0009636]	cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; NADP binding [GO:0050661]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]
d2e6fa__d4yila___1		Fungi		Ascomycota	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]
d2e6fa__d5k1ma___1				Proteobacteria	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; FMN binding [GO:0010181]; riboflavin reductase (NADPH) activity [GO:0042602]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]	cytosol [GO:0005829]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; riboflavin reductase (NADPH) activity [GO:0042602]
d2e6ux__d1wdla3__1			Euryarchaeota	Proteobacteria	cofactor binding [GO:0048037]; metal ion binding [GO:0046872]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation multienzyme complex [GO:0036125]	cofactor binding [GO:0048037]; metal ion binding [GO:0046872]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d2e77d__d5ebue___1			Firmicutes	Firmicutes	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2e7da__d3qznb___1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme binding [GO:0020037]	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]			cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	cell wall [GO:0005618]; extracellular region [GO:0005576]	heme binding [GO:0020037]	metal ion binding [GO:0046872]
d2e7ea__d3i8rc___1	Metazoa		Chordata	Actinobacteria	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	heme oxidation [GO:0006788]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]		enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d2e7ga1_d1josa___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; rRNA processing [GO:0006364]	cytosol [GO:0005829]; ribosomal small subunit binding [GO:0043024]; maturation of SSU-rRNA [GO:0030490]; ribosome biogenesis [GO:0042254]	rRNA processing [GO:0006364]	maturation of SSU-rRNA [GO:0030490]; ribosome biogenesis [GO:0042254]	mitochondrion [GO:0005739]	cytosol [GO:0005829]		ribosomal small subunit binding [GO:0043024]
d2e7ga1_d2kzfa1__1	Metazoa		Chordata	Thermotogae	mitochondrion [GO:0005739]; rRNA processing [GO:0006364]	cytosol [GO:0005829]; ribosomal small subunit binding [GO:0043024]; maturation of SSU-rRNA [GO:0030490]; ribosome biogenesis [GO:0042254]	rRNA processing [GO:0006364]	maturation of SSU-rRNA [GO:0030490]; ribosome biogenesis [GO:0042254]	mitochondrion [GO:0005739]	cytosol [GO:0005829]		ribosomal small subunit binding [GO:0043024]
d2e7ha1_d2erjc1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ephrin receptor activity [GO:0005003]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; ephrin receptor signaling pathway [GO:0048013]; heart morphogenesis [GO:0003007]; protein autophosphorylation [GO:0046777]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]; interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; ephrin receptor signaling pathway [GO:0048013]; heart morphogenesis [GO:0003007]; protein autophosphorylation [GO:0046777]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; ephrin receptor activity [GO:0005003]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]
d2e7ha1_d2ocfd___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ephrin receptor activity [GO:0005003]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; ephrin receptor signaling pathway [GO:0048013]; heart morphogenesis [GO:0003007]; protein autophosphorylation [GO:0046777]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; ephrin receptor signaling pathway [GO:0048013]; heart morphogenesis [GO:0003007]; protein autophosphorylation [GO:0046777]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	ATP binding [GO:0005524]; ephrin receptor activity [GO:0005003]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]
d2e7la__d1bx2a1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d2e7lc__d2cjuh___1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2e7lc__d2hvja2__1	Metazoa		Chordata	Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d2e7pd__d1f2ed2__1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione transferase activity [GO:0004364]
d2e7pd__d4ofmb1__1	Viridiplantae	Metazoa	Streptophyta	Nematoda (roundworms)	cell [GO:0005623]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	transferase activity [GO:0016740]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	transferase activity [GO:0016740]
d2e7qd__d3akra___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]
d2e7ua__d3zzka___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	protoporphyrinogen IX biosynthetic process [GO:0006782]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d2e7wa2_d1n5qa___1			Crenarchaeota	Actinobacteria	DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	monooxygenase activity [GO:0004497]					DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	monooxygenase activity [GO:0004497]
d2e7wa2_d2znyh2__1			Crenarchaeota	Euryarchaeota	DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]					DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d2e86a1_d2xx1f1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2e86a1_d3heid1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	periplasmic space [GO:0042597]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]
d2e88a1_d5aqla2__1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d2e88a2_d4wq5d2__1	Metazoa		Chordata	Proteobacteria	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	cytosol [GO:0005829]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]
d2e89c2_d1wy5a2__1			Aquificae	Aquificae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; tRNA modification [GO:0006400]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; tRNA modification [GO:0006400]	tRNA modification [GO:0006400]	tRNA modification [GO:0006400]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]
d2e8ba__d2xwlb1__1			Aquificae	Actinobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; molybdenum cofactor guanylyltransferase activity [GO:0061603]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [GO:0050518]; nucleotide binding [GO:0000166]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	cytoplasm [GO:0005737]		GTP binding [GO:0005525]; metal ion binding [GO:0046872]; molybdenum cofactor guanylyltransferase activity [GO:0061603]	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [GO:0050518]; nucleotide binding [GO:0000166]
d2e8hb__d2e15b___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2e8ja__d3l9ka___1	Metazoa	Metazoa	Chordata	Arthropoda	centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; membrane [GO:0016020]; microtubule [GO:0005874]; dynein intermediate chain binding [GO:0045505]; microtubule motor activity [GO:0003777]; intraciliary transport involved in cilium assembly [GO:0035735]; microtubule-based movement [GO:0007018]; visual behavior [GO:0007632]	axonemal dynein complex [GO:0005858]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; microtubule [GO:0005874]; dynein intermediate chain binding [GO:0045505]; motor activity [GO:0003774]; dendrite morphogenesis [GO:0048813]; microtubule-based movement [GO:0007018]; mushroom body development [GO:0016319]	intraciliary transport involved in cilium assembly [GO:0035735]; microtubule-based movement [GO:0007018]; visual behavior [GO:0007632]	dendrite morphogenesis [GO:0048813]; microtubule-based movement [GO:0007018]; mushroom body development [GO:0016319]	centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; membrane [GO:0016020]; microtubule [GO:0005874]	axonemal dynein complex [GO:0005858]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; microtubule [GO:0005874]	dynein intermediate chain binding [GO:0045505]; microtubule motor activity [GO:0003777]	dynein intermediate chain binding [GO:0045505]; motor activity [GO:0003774]
d2e8qa__d2elea___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2e8sa__d2ek4a___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2e99a__d5hc6a___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; Gram-negative-bacterium-type cell wall biogenesis [GO:0043164]; peptidoglycan biosynthetic process [GO:0009252]; polyprenol biosynthetic process [GO:0016094]; regulation of cell shape [GO:0008360]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; Gram-negative-bacterium-type cell wall biogenesis [GO:0043164]; peptidoglycan biosynthetic process [GO:0009252]; polyprenol biosynthetic process [GO:0016094]; regulation of cell shape [GO:0008360]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		di-trans,poly-cis-decaprenylcistransferase activity [GO:0008834]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; polyprenyltransferase activity [GO:0002094]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]
d2e9fa__d1hy1d___1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; argininosuccinate lyase activity [GO:0004056]; arginine biosynthetic process via ornithine [GO:0042450]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	arginine biosynthetic process via ornithine [GO:0042450]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	cytoplasm [GO:0005737]		argininosuccinate lyase activity [GO:0004056]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]
d2e9fb__d1fuoa___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; argininosuccinate lyase activity [GO:0004056]; arginine biosynthetic process via ornithine [GO:0042450]	tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	arginine biosynthetic process via ornithine [GO:0042450]	fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	tricarboxylic acid cycle enzyme complex [GO:0045239]	argininosuccinate lyase activity [GO:0004056]	fumarate hydratase activity [GO:0004333]
d2e9fc__d5d6ba___1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; argininosuccinate lyase activity [GO:0004056]; arginine biosynthetic process via ornithine [GO:0042450]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; histone binding [GO:0042393]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; fumarate metabolic process [GO:0006106]; homeostasis of number of cells within a tissue [GO:0048873]; malate metabolic process [GO:0006108]; negative regulation of histone H3-K36 methylation [GO:0000415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of arginine metabolic process [GO:0000821]; tricarboxylic acid cycle [GO:0006099]; urea cycle [GO:0000050]	arginine biosynthetic process via ornithine [GO:0042450]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; fumarate metabolic process [GO:0006106]; homeostasis of number of cells within a tissue [GO:0048873]; malate metabolic process [GO:0006108]; negative regulation of histone H3-K36 methylation [GO:0000415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of arginine metabolic process [GO:0000821]; tricarboxylic acid cycle [GO:0006099]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; tricarboxylic acid cycle enzyme complex [GO:0045239]	argininosuccinate lyase activity [GO:0004056]	fumarate hydratase activity [GO:0004333]; histone binding [GO:0042393]
d2e9ja1_d1u3za___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2e9qa2_d4tlfd___1	Viridiplantae		Streptophyta	Proteobacteria	metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]	ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]			metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]	ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d2e9xb1_d2q9qd1__1	Metazoa	Metazoa	Chordata	Chordata	GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; replication fork protection complex [GO:0031298]; DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]	GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; replication fork protection complex [GO:0031298]; DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]	DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]	DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]	GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; replication fork protection complex [GO:0031298]	GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; replication fork protection complex [GO:0031298]		
d2ea3a__d2vj1b___1			Actinobacteria		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]		7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	extracellular region [GO:0005576]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2eakc__d2phra___1	Metazoa	Viridiplantae	Chordata	Streptophyta	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2ealb__d2phxa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2eava__d3rdra___1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; membrane [GO:0016020]; protein-containing complex [GO:0032991]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; peptidoglycan receptor activity [GO:0016019]; protein heterodimerization activity [GO:0046982]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of natural killer cell differentiation involved in immune response [GO:0032827]; peptidoglycan catabolic process [GO:0009253]; positive regulation of cytolysis in other organism [GO:0051714]	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; cell wall organization [GO:0071555]; establishment of competence for transformation [GO:0030420]; peptidoglycan catabolic process [GO:0009253]; peptidoglycan turnover [GO:0009254]; sporulation resulting in formation of a cellular spore [GO:0030435]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of natural killer cell differentiation involved in immune response [GO:0032827]; peptidoglycan catabolic process [GO:0009253]; positive regulation of cytolysis in other organism [GO:0051714]	cell wall organization [GO:0071555]; establishment of competence for transformation [GO:0030420]; peptidoglycan catabolic process [GO:0009253]; peptidoglycan turnover [GO:0009254]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular space [GO:0005615]; membrane [GO:0016020]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; peptidoglycan receptor activity [GO:0016019]; protein heterodimerization activity [GO:0046982]; zinc ion binding [GO:0008270]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]
d2eb6b__d2wqta___1			Proteobacteria	Proteobacteria	2-hydroxyhexa-2,4-dienoate hydratase activity [GO:0034856]; 2-oxo-hept-3-ene-1,7-dioate hydratase activity [GO:0018817]; 2-oxopent-4-enoate hydratase activity [GO:0008684]; 4-oxalocrotonate decarboxylase activity [GO:0047437]; metal ion binding [GO:0046872]; aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]; 2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]		cytoplasm [GO:0005737]	2-hydroxyhexa-2,4-dienoate hydratase activity [GO:0034856]; 2-oxo-hept-3-ene-1,7-dioate hydratase activity [GO:0018817]; 2-oxopent-4-enoate hydratase activity [GO:0008684]; 4-oxalocrotonate decarboxylase activity [GO:0047437]; metal ion binding [GO:0046872]	2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]
d2ebac2_d3mpjf2__1			Deinococcus-Thermus	Proteobacteria	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d2ebae2_d1udya1__1		Metazoa	Deinococcus-Thermus	Chordata	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]		fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]
d2ebag2_d5k3hb3__1		Metazoa	Deinococcus-Thermus	Nematoda (roundworms)	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]		ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]		peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]
d2ebai2_d2d29a1__1			Deinococcus-Thermus	Deinococcus-Thermus	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]					acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d2ebma1_d4gpra1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; polysome [GO:0005844]; androgen receptor signaling pathway [GO:0030521]; cell aging [GO:0007569]; cellular response to oxidative stress [GO:0034599]; cellular response to testosterone stimulus [GO:0071394]; cytoplasmic translation [GO:0002181]; positive regulation of androgen receptor activity [GO:2000825]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-dependent protein catabolic process [GO:0006511]	androgen receptor signaling pathway [GO:0030521]; cell aging [GO:0007569]; cellular response to oxidative stress [GO:0034599]; cellular response to testosterone stimulus [GO:0071394]; cytoplasmic translation [GO:0002181]; positive regulation of androgen receptor activity [GO:2000825]	ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; polysome [GO:0005844]			ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]
d2ebyb__d2iu7h1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]		cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2ebyb__d4i6ra___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]	DNA binding [GO:0003677]					DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2ebza1_d1iapa___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTPase regulator activity [GO:0030695]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; RNA binding [GO:0003723]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	cell junction [GO:0030054]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTPase regulator activity [GO:0030695]	G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; RNA binding [GO:0003723]
d2ec9h__d2byax___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2ecda1_d1cj1k___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cytosol [GO:0005829]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein kinase activity [GO:0004672]; protein tyrosine kinase activity [GO:0004713]; cell adhesion [GO:0007155]; cellular protein modification process [GO:0006464]; cellular response to retinoic acid [GO:0071300]; exploration behavior [GO:0035640]; negative regulation of Rho protein signal transduction [GO:0035024]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of neuron projection development [GO:0010976]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of phospholipase C activity [GO:0010863]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cell adhesion [GO:0007155]; cellular protein modification process [GO:0006464]; cellular response to retinoic acid [GO:0071300]; exploration behavior [GO:0035640]; negative regulation of Rho protein signal transduction [GO:0035024]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of neuron projection development [GO:0010976]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of phospholipase C activity [GO:0010863]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cytosol [GO:0005829]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein kinase activity [GO:0004672]; protein tyrosine kinase activity [GO:0004713]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]
d2ecra__d4l82b1__1			Deinococcus-Thermus	Proteobacteria	flavin reductase (NADH) activity [GO:0036382]; FMN binding [GO:0010181]; aromatic compound catabolic process [GO:0019439]	FMN binding [GO:0010181]	aromatic compound catabolic process [GO:0019439]				flavin reductase (NADH) activity [GO:0036382]; FMN binding [GO:0010181]	FMN binding [GO:0010181]
d2ecrb__d3u34b___1			Deinococcus-Thermus	Proteobacteria	flavin reductase (NADH) activity [GO:0036382]; FMN binding [GO:0010181]; aromatic compound catabolic process [GO:0019439]	cofactor binding [GO:0048037]	aromatic compound catabolic process [GO:0019439]				flavin reductase (NADH) activity [GO:0036382]; FMN binding [GO:0010181]	cofactor binding [GO:0048037]
d2ed3b__d2e8rb___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2ed4a__d2d36a1__1			Deinococcus-Thermus	Crenarchaeota	flavin reductase (NADH) activity [GO:0036382]; FMN binding [GO:0010181]; aromatic compound catabolic process [GO:0019439]	FMN binding [GO:0010181]; phenol 2-monooxygenase activity [GO:0018662]	aromatic compound catabolic process [GO:0019439]				flavin reductase (NADH) activity [GO:0036382]; FMN binding [GO:0010181]	FMN binding [GO:0010181]; phenol 2-monooxygenase activity [GO:0018662]
d2ed4a__d5jabc___1			Deinococcus-Thermus	Actinobacteria	flavin reductase (NADH) activity [GO:0036382]; FMN binding [GO:0010181]; aromatic compound catabolic process [GO:0019439]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; coenzyme F420 binding [GO:0070967]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; protein homodimerization activity [GO:0042803]; oxidation-reduction process [GO:0055114]	aromatic compound catabolic process [GO:0019439]	oxidation-reduction process [GO:0055114]		cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]	flavin reductase (NADH) activity [GO:0036382]; FMN binding [GO:0010181]	coenzyme F420 binding [GO:0070967]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; protein homodimerization activity [GO:0042803]
d2ed4b__d3k87a___1			Deinococcus-Thermus	Proteobacteria	flavin reductase (NADH) activity [GO:0036382]; FMN binding [GO:0010181]; aromatic compound catabolic process [GO:0019439]	FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [GO:0016646]; protein homodimerization activity [GO:0042803]; aromatic compound catabolic process [GO:0019439]; oxidation-reduction process [GO:0055114]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]; oxidation-reduction process [GO:0055114]			flavin reductase (NADH) activity [GO:0036382]; FMN binding [GO:0010181]	FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [GO:0016646]; protein homodimerization activity [GO:0042803]
d2edaa__d1ea5a___1		Metazoa	Proteobacteria	Chordata	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	haloalkane dehalogenase activity [GO:0018786]	acetylcholinesterase activity [GO:0003990]
d2edia1_d5ojja___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; NEDD8 conjugating enzyme activity [GO:0061654]; NEDD8 transferase activity [GO:0019788]; post-translational protein modification [GO:0043687]; protein neddylation [GO:0045116]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K6-linked ubiquitination [GO:0085020]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]	post-translational protein modification [GO:0043687]; protein neddylation [GO:0045116]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]	cytosol [GO:0005829]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; NEDD8 conjugating enzyme activity [GO:0061654]; NEDD8 transferase activity [GO:0019788]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]
d2edka1_d1txvl3__1	Metazoa		Chordata		cytosol [GO:0005829]; myosin filament [GO:0032982]; actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]		cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]		cytosol [GO:0005829]; myosin filament [GO:0032982]		actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]	
d2edma1_d2ed6e___1					integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]		
d2edpa1_d1qlca___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; stress fiber [GO:0001725]; actin filament binding [GO:0051015]; myosin II binding [GO:0045159]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; brain development [GO:0007420]; cognition [GO:0050890]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; brain development [GO:0007420]; cognition [GO:0050890]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	actin filament [GO:0005884]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; stress fiber [GO:0001725]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	actin filament binding [GO:0051015]; myosin II binding [GO:0045159]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]
d2edqa1_d3ch1d2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2edra1_d4jr9l1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; inorganic anion exchanger activity [GO:0005452]; nitrate transmembrane transporter activity [GO:0015112]; nitrite efflux transmembrane transporter activity [GO:0015514]; nitrate assimilation [GO:0042128]; nitrate transport [GO:0015706]; nitrite transport [GO:0015707]	G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	nitrate assimilation [GO:0042128]; nitrate transport [GO:0015706]; nitrite transport [GO:0015707]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	inorganic anion exchanger activity [GO:0005452]; nitrate transmembrane transporter activity [GO:0015112]; nitrite efflux transmembrane transporter activity [GO:0015514]
d2edva1_d4nnma___1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; establishment of protein localization to membrane [GO:0090150]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]; activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	establishment of protein localization to membrane [GO:0090150]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]		beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]
d2edza1_d1k32b1__1	Metazoa		Chordata	Euryarchaeota	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]; carnitine transport [GO:0015879]; in utero embryonic development [GO:0001701]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; protein localization to plasma membrane [GO:0072659]; regulation of anion transport [GO:0044070]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	carnitine transport [GO:0015879]; in utero embryonic development [GO:0001701]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; protein localization to plasma membrane [GO:0072659]; regulation of anion transport [GO:0044070]	proteolysis [GO:0006508]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]	serine-type peptidase activity [GO:0008236]
d2ee2a1_d5dftj___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	carbohydrate binding [GO:0030246]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]
d2ee5a1_d1grnb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; SH2 domain binding [GO:0042169]; cell adhesion [GO:0007155]; mammary gland development [GO:0030879]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cell adhesion [GO:0007155]; mammary gland development [GO:0030879]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; SH2 domain binding [GO:0042169]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]
d2ee6a1_d2d7pa1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]
d2ee6a1_d4gt0a2__1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2ee9a1_d2yowa___1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]		actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]		actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]		actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	
d2eeaa1_d1im3p___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2eega1_d1vj6a1__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendritic spine [GO:0043197]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; filamentous actin [GO:0031941]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic membrane [GO:0045211]; recycling endosome lumen [GO:0034777]; recycling endosome membrane [GO:0055038]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; excitatory chemical synaptic transmission [GO:0098976]; heart development [GO:0007507]; muscle structure development [GO:0061061]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; midbody [GO:0030496]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; excitatory chemical synaptic transmission [GO:0098976]; heart development [GO:0007507]; muscle structure development [GO:0061061]	negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendritic spine [GO:0043197]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; filamentous actin [GO:0031941]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic membrane [GO:0045211]; recycling endosome lumen [GO:0034777]; recycling endosome membrane [GO:0055038]; stress fiber [GO:0001725]; Z disc [GO:0030018]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; midbody [GO:0030496]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]
d2eeha1_d1t2ma1__1	Metazoa	Metazoa	Chordata	Chordata	cilium [GO:0005929]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stereocilia ankle link [GO:0002141]; stereocilia ankle link complex [GO:0002142]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426]; USH2 complex [GO:1990696]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; auditory receptor cell development [GO:0060117]; auditory receptor cell stereocilium organization [GO:0060088]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; establishment of protein localization [GO:0045184]; sensory perception of sound [GO:0007605]	cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; pore complex [GO:0046930]; tight junction [GO:0070160]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; protein C-terminus binding [GO:0008022]; Ras GTPase binding [GO:0017016]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of protein localization to plasma membrane [GO:0061951]; negative regulation of cell migration [GO:0030336]; pore complex assembly [GO:0046931]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165]	auditory receptor cell development [GO:0060117]; auditory receptor cell stereocilium organization [GO:0060088]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; establishment of protein localization [GO:0045184]; sensory perception of sound [GO:0007605]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of protein localization to plasma membrane [GO:0061951]; negative regulation of cell migration [GO:0030336]; pore complex assembly [GO:0046931]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165]	cilium [GO:0005929]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stereocilia ankle link [GO:0002141]; stereocilia ankle link complex [GO:0002142]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426]; USH2 complex [GO:1990696]	cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; pore complex [GO:0046930]; tight junction [GO:0070160]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; protein C-terminus binding [GO:0008022]; Ras GTPase binding [GO:0017016]
d2eeia1_d5heta1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]; carnitine transport [GO:0015879]; cell population proliferation [GO:0008283]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of anion transport [GO:0044070]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	carnitine transport [GO:0015879]; cell population proliferation [GO:0008283]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of anion transport [GO:0044070]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]
d2ef0a1_d3r7le1__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d2ef1a1_d3f6ya___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d2ef9a__d3lbmd___1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d2efeb__d4d6ha1__1	Viridiplantae		Streptophyta		cytoplasm [GO:0005737]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; intracellular organelle [GO:0043229]; multivesicular body membrane [GO:0032585]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; intracellular protein transport [GO:0006886]; late endosome to vacuole transport [GO:0045324]; Rab protein signal transduction [GO:0032482]; vacuole organization [GO:0007033]		intracellular protein transport [GO:0006886]; late endosome to vacuole transport [GO:0045324]; Rab protein signal transduction [GO:0032482]; vacuole organization [GO:0007033]		cytoplasm [GO:0005737]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; intracellular organelle [GO:0043229]; multivesicular body membrane [GO:0032585]; plasma membrane [GO:0005886]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]	
d2efed__d2h17a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; intracellular organelle [GO:0043229]; multivesicular body membrane [GO:0032585]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; intracellular protein transport [GO:0006886]; late endosome to vacuole transport [GO:0045324]; Rab protein signal transduction [GO:0032482]; vacuole organization [GO:0007033]	cytoplasm [GO:0005737]; trans-Golgi network [GO:0005802]; GTP binding [GO:0005525]; intracellular protein transport [GO:0006886]; protein localization to Golgi membrane [GO:1903292]; vesicle-mediated transport [GO:0016192]	intracellular protein transport [GO:0006886]; late endosome to vacuole transport [GO:0045324]; Rab protein signal transduction [GO:0032482]; vacuole organization [GO:0007033]	intracellular protein transport [GO:0006886]; protein localization to Golgi membrane [GO:1903292]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; intracellular organelle [GO:0043229]; multivesicular body membrane [GO:0032585]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; trans-Golgi network [GO:0005802]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GTP binding [GO:0005525]
d2efga4_d1zm2c5__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]			cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d2efga4_d3b78e5__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]			cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d2efpa2_d1tr0x___1		Viridiplantae	Crenarchaeota	Streptophyta	DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]						DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	
d2efta1_d3v4nb2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	isoprenoid biosynthetic process [GO:0008299]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d2efta2_d1d6fa2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	naringenin-chalcone synthase activity [GO:0016210]
d2eftb1_d1xetb1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	pinosylvin synthase activity [GO:0050198]
d2eftb1_d1xpma2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	isoprenoid biosynthetic process [GO:0008299]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d2efwf__d4omzh___1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; DNA replication termination [GO:0006274]	DNA-binding transcription factor activity [GO:0003700]	DNA replication termination [GO:0006274]				DNA binding [GO:0003677]	DNA-binding transcription factor activity [GO:0003700]
d2eg0b__d2tdta___1						cytoplasm [GO:0005737]; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]		2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]
d2egbb__d2dsha___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2egdb__d1f4oa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; membrane fusion [GO:0061025]; neutrophil degranulation [GO:0043312]	cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	membrane fusion [GO:0061025]; neutrophil degranulation [GO:0043312]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d2egie__d4cl6b___1			Aquificae	Proteobacteria	acyl-CoA hydrolase activity [GO:0047617]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]		unsaturated fatty acid biosynthetic process [GO:0006636]		cytoplasm [GO:0005737]	acyl-CoA hydrolase activity [GO:0047617]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]
d2egie__d5byue___1			Aquificae	Proteobacteria	acyl-CoA hydrolase activity [GO:0047617]						acyl-CoA hydrolase activity [GO:0047617]	
d2egja__d1pn4c2__1		Fungi	Aquificae	Ascomycota	acyl-CoA hydrolase activity [GO:0047617]	peroxisome [GO:0005777]; isomerase activity [GO:0016853]; lyase activity [GO:0016829]; oxidoreductase activity [GO:0016491]; fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation [GO:0006635]		peroxisome [GO:0005777]	acyl-CoA hydrolase activity [GO:0047617]	isomerase activity [GO:0016853]; lyase activity [GO:0016829]; oxidoreductase activity [GO:0016491]
d2egjb__d2xemb___1			Aquificae	Actinobacteria	acyl-CoA hydrolase activity [GO:0047617]						acyl-CoA hydrolase activity [GO:0047617]	
d2egjb__d4fq9b___1			Aquificae	Proteobacteria	acyl-CoA hydrolase activity [GO:0047617]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]		unsaturated fatty acid biosynthetic process [GO:0006636]		cytoplasm [GO:0005737]	acyl-CoA hydrolase activity [GO:0047617]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]
d2egra__d1vi8f1__1			Aquificae	Proteobacteria	acyl-CoA hydrolase activity [GO:0047617]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]; menaquinone biosynthetic process [GO:0009234]		menaquinone biosynthetic process [GO:0009234]		cytosol [GO:0005829]	acyl-CoA hydrolase activity [GO:0047617]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]
d2egrb__d3r3fa___1			Aquificae	Actinobacteria	acyl-CoA hydrolase activity [GO:0047617]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]					acyl-CoA hydrolase activity [GO:0047617]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]
d2eh0a1_d3mdba___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; axon cytoplasm [GO:1904115]; cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; synaptic vesicle [GO:0008021]; ATP binding [GO:0005524]; ATP-dependent microtubule motor activity, plus-end-directed [GO:0008574]; ATPase activity [GO:0016887]; kinase binding [GO:0019900]; kinesin binding [GO:0019894]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; scaffold protein binding [GO:0097110]; anterograde axonal transport [GO:0008089]; anterograde neuronal dense core vesicle transport [GO:1990048]; apoptotic process [GO:0006915]; cellular response to nerve growth factor stimulus [GO:1990090]; cytoskeleton-dependent intracellular transport [GO:0030705]; lysosome localization [GO:0032418]; microtubule-based movement [GO:0007018]; mitochondrion transport along microtubule [GO:0047497]; neuromuscular synaptic transmission [GO:0007274]; neuron-neuron synaptic transmission [GO:0007270]; positive regulation of gene expression [GO:0010628]; protein localization to cell periphery [GO:1990778]; response to rotenone [GO:1904647]; retrograde neuronal dense core vesicle transport [GO:1990049]; vesicle-mediated transport [GO:0016192]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; microvillus [GO:0005902]; paranode region of axon [GO:0033270]; 14-3-3 protein binding [GO:0071889]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; protein kinase binding [GO:0019901]; microtubule-based movement [GO:0007018]; protein targeting [GO:0006605]; regulation of axonogenesis [GO:0050770]; signal transduction [GO:0007165]; T cell activation [GO:0042110]	anterograde axonal transport [GO:0008089]; anterograde neuronal dense core vesicle transport [GO:1990048]; apoptotic process [GO:0006915]; cellular response to nerve growth factor stimulus [GO:1990090]; cytoskeleton-dependent intracellular transport [GO:0030705]; lysosome localization [GO:0032418]; microtubule-based movement [GO:0007018]; mitochondrion transport along microtubule [GO:0047497]; neuromuscular synaptic transmission [GO:0007274]; neuron-neuron synaptic transmission [GO:0007270]; positive regulation of gene expression [GO:0010628]; protein localization to cell periphery [GO:1990778]; response to rotenone [GO:1904647]; retrograde neuronal dense core vesicle transport [GO:1990049]; vesicle-mediated transport [GO:0016192]	microtubule-based movement [GO:0007018]; protein targeting [GO:0006605]; regulation of axonogenesis [GO:0050770]; signal transduction [GO:0007165]; T cell activation [GO:0042110]	axon [GO:0030424]; axon cytoplasm [GO:1904115]; cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; synaptic vesicle [GO:0008021]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; microvillus [GO:0005902]; paranode region of axon [GO:0033270]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; ATP-dependent microtubule motor activity, plus-end-directed [GO:0008574]; kinase binding [GO:0019900]; kinesin binding [GO:0019894]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; scaffold protein binding [GO:0097110]	14-3-3 protein binding [GO:0071889]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; protein kinase binding [GO:0019901]
d2eh2b__d2dv3b___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2eh4a__d2deka___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2eh4a__d2pcmb___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2eh5b__d2ek2a___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2eh6b__d2bylc___1		Metazoa	Aquificae	Chordata	cytoplasm [GO:0005737]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	arginine biosynthetic process [GO:0006526]	arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]	ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]
d2ehga__d4we1a2__1			Crenarchaeota		cytoplasm [GO:0005737]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2ehib3_d1upsb2__1				Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2ehka__d1b78a___1				Euryarchaeota		dITP diphosphatase activity [GO:0035870]; ITP diphosphatase activity [GO:0036220]; metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; XTP diphosphatase activity [GO:0036222]; nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]		nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]				dITP diphosphatase activity [GO:0035870]; ITP diphosphatase activity [GO:0036220]; metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; XTP diphosphatase activity [GO:0036222]
d2ehla__d2dv7b___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2ehma3_d4z8sb2__1		Viridiplantae		Streptophyta		rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]				rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2ehma4_d2d24a2__1				Actinobacteria		endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]				endo-1,4-beta-xylanase activity [GO:0031176]
d2ehma4_d2f2fc1__1				Proteobacteria		negative regulation by symbiont of host cell cycle [GO:0044072]; pathogenesis [GO:0009405]		negative regulation by symbiont of host cell cycle [GO:0044072]; pathogenesis [GO:0009405]				
d2ehmb4_d4lo3b1__1				Firmicutes								
d2ehnb3_d1vclb2__1		Metazoa		Echinodermata		carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]						carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2ehqb__d1wndd___1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	cytosol [GO:0005829]; 1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; putrescine catabolic process [GO:0009447]		putrescine catabolic process [GO:0009447]		cytosol [GO:0005829]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]
d2ehra1_d3dj3a___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]; activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]
d2ehsa__d2dnwa1__1		Metazoa	Aquificae	Chordata	cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; phosphopantetheine binding [GO:0031177]; lipid A biosynthetic process [GO:0009245]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; calcium ion binding [GO:0005509]; fatty acid binding [GO:0005504]; NADH dehydrogenase (ubiquinone) activity [GO:0008137]; fatty acid biosynthetic process [GO:0006633]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; protein lipoylation [GO:0009249]	lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; protein lipoylation [GO:0009249]	cytosol [GO:0005829]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; phosphopantetheine binding [GO:0031177]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; calcium ion binding [GO:0005509]; fatty acid binding [GO:0005504]; NADH dehydrogenase (ubiquinone) activity [GO:0008137]
d2ehub__d4kwfh___1		Metazoa	Deinococcus-Thermus	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2ei0a1_d1f1xb2__1			Proteobacteria	Actinobacteria	1,2-dihydroxynaphthalene dioxygenase activity [GO:0018554]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; naphthalene catabolic process [GO:1901170]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	naphthalene catabolic process [GO:1901170]				1,2-dihydroxynaphthalene dioxygenase activity [GO:0018554]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d2ei2a1_d2ig9c2__1			Proteobacteria	Actinobacteria	1,2-dihydroxynaphthalene dioxygenase activity [GO:0018554]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; naphthalene catabolic process [GO:1901170]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	naphthalene catabolic process [GO:1901170]				1,2-dihydroxynaphthalene dioxygenase activity [GO:0018554]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d2ei3a2_d5trxa1__1			Proteobacteria	Actinobacteria	1,2-dihydroxynaphthalene dioxygenase activity [GO:0018554]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; naphthalene catabolic process [GO:1901170]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	naphthalene catabolic process [GO:1901170]				1,2-dihydroxynaphthalene dioxygenase activity [GO:0018554]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d2ei7a__d1xmn.3__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d2ei8a__d5dp3a1__1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2ei9a__d2isib___1	Metazoa	Metazoa	Arthropoda	Chordata	RNA-directed DNA polymerase activity [GO:0003964]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]		aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]		cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	RNA-directed DNA polymerase activity [GO:0003964]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]
d2eiab1_d3g1ia___1					viral nucleocapsid [GO:0019013]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral budding via host ESCRT complex [GO:0039702]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]; aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral procapsid maturation [GO:0046797]	viral budding via host ESCRT complex [GO:0039702]	viral procapsid maturation [GO:0046797]	viral nucleocapsid [GO:0019013]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]	nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d2eica1_d3uypb___1	Fungi		Ascomycota		extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2eida1_d2eeca1__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]		actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d2eida1_d3jv4d___1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	extracellular region [GO:0005576]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d2eiea1_d1wcqc1__1	Fungi		Ascomycota	Actinobacteria	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]		metabolic process [GO:0008152]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d2eiea2_d1f49a3__1	Fungi		Ascomycota		extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]				extracellular region [GO:0005576]		galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	
d2eifa1_d1iz6b1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; translational frameshifting [GO:0006452]	cytoplasm [GO:0005737]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; translational frameshifting [GO:0006452]	positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; translational frameshifting [GO:0006452]	positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; translational frameshifting [GO:0006452]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d2eiga__d3vzma___1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d2eilo1_d1jera___1	Metazoa	Viridiplantae	Chordata	Streptophyta	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]		copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2eimo1_d5i6na2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2einb1_d2bp0a2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	ATP synthesis coupled electron transport [GO:0042773]	nitrogen compound metabolic process [GO:0006807]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]		copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2eino1_d4p5sa___1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2eipb__d4z74b1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d2eiqa__d4aj6a___1		Metazoa	Proteobacteria	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	protein disulfide oxidoreductase activity [GO:0015035]
d2eira__d1q98b___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	thioredoxin peroxidase activity [GO:0008379]
d2eirc__d2imib1__1		Metazoa	Proteobacteria	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	glutathione transferase activity [GO:0004364]
d2eita__d4i25c___1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]					nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2eitb__d3n83f___1		Metazoa	Deinococcus-Thermus	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2eiwa__d5j6ba1__1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]					nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2eixa1_d3vo2a1__1		Viridiplantae		Streptophyta	integral component of membrane [GO:0016021]; 2 iron, 2 sulfur cluster binding [GO:0051537]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; flavin adenine dinucleotide binding [GO:0050660]; pyrimidine nucleotide biosynthetic process [GO:0006221]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	pyrimidine nucleotide biosynthetic process [GO:0006221]		integral component of membrane [GO:0016021]	chloroplast [GO:0009507]	2 iron, 2 sulfur cluster binding [GO:0051537]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; flavin adenine dinucleotide binding [GO:0050660]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d2eixa2_d4yawb3__1		Metazoa		Chordata	integral component of membrane [GO:0016021]; 2 iron, 2 sulfur cluster binding [GO:0051537]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; flavin adenine dinucleotide binding [GO:0050660]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	pyrimidine nucleotide biosynthetic process [GO:0006221]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	integral component of membrane [GO:0016021]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; flavin adenine dinucleotide binding [GO:0050660]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d2eixa2_d5ue9b2__1				Firmicutes	integral component of membrane [GO:0016021]; 2 iron, 2 sulfur cluster binding [GO:0051537]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; flavin adenine dinucleotide binding [GO:0050660]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; flavin adenine dinucleotide binding [GO:0050660]	dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]
d2eixb2_d2bgia2__1				Proteobacteria	integral component of membrane [GO:0016021]; 2 iron, 2 sulfur cluster binding [GO:0051537]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; flavin adenine dinucleotide binding [GO:0050660]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	pyrimidine nucleotide biosynthetic process [GO:0006221]		integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; flavin adenine dinucleotide binding [GO:0050660]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d2eiza__d1axth2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2eizb1_d3lrho___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	autophagosome [GO:0005776]; axon [GO:0030424]; cell [GO:0005623]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; late endosome [GO:0005770]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; protein-containing complex [GO:0032991]; beta-tubulin binding [GO:0048487]; dynactin binding [GO:0034452]; dynein intermediate chain binding [GO:0045505]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; p53 binding [GO:0002039]; profilin binding [GO:0005522]; apoptotic process [GO:0006915]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of aggrephagy [GO:1905337]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of lipophagy [GO:1904504]; protein destabilization [GO:0031648]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of phosphoprotein phosphatase activity [GO:0043666]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle transport along microtubule [GO:0047496]; vocal learning [GO:0042297]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	apoptotic process [GO:0006915]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of aggrephagy [GO:1905337]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of lipophagy [GO:1904504]; protein destabilization [GO:0031648]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of phosphoprotein phosphatase activity [GO:0043666]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle transport along microtubule [GO:0047496]; vocal learning [GO:0042297]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	autophagosome [GO:0005776]; axon [GO:0030424]; cell [GO:0005623]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; late endosome [GO:0005770]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; protein-containing complex [GO:0032991]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-tubulin binding [GO:0048487]; dynactin binding [GO:0034452]; dynein intermediate chain binding [GO:0045505]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; p53 binding [GO:0002039]; profilin binding [GO:0005522]
d2eizc__d189la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2ej6b__d4it9a___1			Deinococcus-Thermus	Cyanobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]					nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2ejea1_d1q60a1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; mitogen-activated protein kinase binding [GO:0051019]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; transcription by RNA polymerase II [GO:0006366]; transition between slow and fast fiber [GO:0014886]	negative regulation of angiogenesis [GO:0016525]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	negative regulation of angiogenesis [GO:0016525]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; transcription by RNA polymerase II [GO:0006366]; transition between slow and fast fiber [GO:0014886]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; mitogen-activated protein kinase binding [GO:0051019]
d2ejfb2_d1pysb5__1			Euryarchaeota	Deinococcus-Thermus		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]		phenylalanyl-tRNA aminoacylation [GO:0006432]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]
d2ejga1_d4hwoa1__1			Euryarchaeota	Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]		negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2ejra3_d2c75b2__1	Metazoa	Metazoa	Chordata	Chordata	DNA repair complex [GO:1990391]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; androgen receptor binding [GO:0050681]; chromatin binding [GO:0003682]; demethylase activity [GO:0032451]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-dimethyl-K4 specific) [GO:0034648]; histone demethylase activity (H3-K4 specific) [GO:0032453]; histone demethylase activity (H3-K9 specific) [GO:0032454]; MRF binding [GO:0043426]; nuclear receptor transcription coactivator activity [GO:0030374]; oxidoreductase activity [GO:0016491]; p53 binding [GO:0002039]; RNA polymerase II transcription factor binding [GO:0001085]; telomeric DNA binding [GO:0042162]; telomeric repeat-containing RNA binding [GO:0061752]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; alternative mRNA splicing, via spliceosome [GO:0000380]; blood coagulation [GO:0007596]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; histone H3-K9 demethylation [GO:0033169]; muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron maturation [GO:0042551]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of histone ubiquitination [GO:0033184]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of cellular protein localization [GO:1903827]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fungicide [GO:0060992]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	alternative mRNA splicing, via spliceosome [GO:0000380]; blood coagulation [GO:0007596]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; histone H3-K9 demethylation [GO:0033169]; muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron maturation [GO:0042551]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of histone ubiquitination [GO:0033184]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of cellular protein localization [GO:1903827]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fungicide [GO:0060992]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	DNA repair complex [GO:1990391]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	androgen receptor binding [GO:0050681]; chromatin binding [GO:0003682]; demethylase activity [GO:0032451]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-dimethyl-K4 specific) [GO:0034648]; histone demethylase activity (H3-K4 specific) [GO:0032453]; histone demethylase activity (H3-K9 specific) [GO:0032454]; MRF binding [GO:0043426]; nuclear receptor transcription coactivator activity [GO:0030374]; oxidoreductase activity [GO:0016491]; p53 binding [GO:0002039]; RNA polymerase II transcription factor binding [GO:0001085]; telomeric DNA binding [GO:0042162]; telomeric repeat-containing RNA binding [GO:0061752]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d2ek2b__d2dxwa___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2ek3a__d2huqb___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2ek6a1_d2j0qg1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; RNA binding [GO:0003723]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]		mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]	nucleoplasm [GO:0005654]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]	RNA binding [GO:0003723]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d2ekaa__d2eh2a___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2ekbb__d1h2fa___1			Deinococcus-Thermus	Firmicutes	catalytic activity [GO:0003824]						catalytic activity [GO:0003824]	
d2ekea__d3p9ga___1	Fungi	Metazoa	Ascomycota	Chordata	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]; identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]; autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	protein sumoylation [GO:0016925]	autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]	calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]
d2ekea__d3ptfb1__1	Fungi	Metazoa	Ascomycota	Chordata	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]; identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	protein sumoylation [GO:0016925]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2ekeb__d5knlc1__1	Fungi	Fungi	Ascomycota	Ascomycota	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]; identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]; protein sumoylation [GO:0016925]	nucleus [GO:0005634]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; negative regulation of chromatin silencing at silent mating-type cassette [GO:0061186]; negative regulation of chromatin silencing at telomere [GO:0031939]; protein modification by small protein conjugation or removal [GO:0070647]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511]	protein sumoylation [GO:0016925]	negative regulation of chromatin silencing at silent mating-type cassette [GO:0061186]; negative regulation of chromatin silencing at telomere [GO:0031939]; protein modification by small protein conjugation or removal [GO:0070647]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]	nucleus [GO:0005634]	identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]
d2ekmb__d1rlha1__1			Crenarchaeota	Euryarchaeota								
d2ekpa__d1v8bb1__1			Deinococcus-Thermus	Apicomplexa	nucleotide binding [GO:0000166]	cytosol [GO:0005829]; adenosylhomocysteinase activity [GO:0004013]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353]		one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353]		cytosol [GO:0005829]	nucleotide binding [GO:0000166]	adenosylhomocysteinase activity [GO:0004013]
d2eksb1_d3bkyh2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ekza__d2wnib1__1			Deinococcus-Thermus	Proteobacteria	catalytic activity [GO:0003824]	3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]					catalytic activity [GO:0003824]	3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]
d2ekzb__d1bq4a___1		Fungi	Deinococcus-Thermus	Ascomycota	catalytic activity [GO:0003824]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]	phosphoglycerate mutase activity [GO:0004619]
d2el0b__d2enib___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2el3b__d1wnga___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2elca1_d3gbrb1__1			Deinococcus-Thermus	Crenarchaeota	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	tryptophan biosynthetic process [GO:0000162]	tryptophan biosynthetic process [GO:0000162]		cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]
d2elcb2_d2wk5a2__1		Metazoa	Deinococcus-Thermus	Chordata	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	tryptophan biosynthetic process [GO:0000162]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]		cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d2elcc1_d1zxyb1__1			Deinococcus-Thermus	Crenarchaeota	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	tryptophan biosynthetic process [GO:0000162]	tryptophan biosynthetic process [GO:0000162]		cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]
d2elcd1_d1zxyc1__1			Deinococcus-Thermus	Crenarchaeota	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	tryptophan biosynthetic process [GO:0000162]	tryptophan biosynthetic process [GO:0000162]		cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]
d2elcd1_d4yyya1__1			Deinococcus-Thermus	Proteobacteria	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]	tryptophan biosynthetic process [GO:0000162]	pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]		cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d2elcd2_d1azyb2__1			Deinococcus-Thermus	Proteobacteria	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; membrane [GO:0016020]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]	tryptophan biosynthetic process [GO:0000162]	cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]		cytosol [GO:0005829]; membrane [GO:0016020]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d2emsa1_d1mk7b1__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]
d2emsa1_d4zrka2__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d2emsa2_d1p3rc___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	apical plasma membrane [GO:0016324]; clathrin coat of coated pit [GO:0030132]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]; activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	apical plasma membrane [GO:0016324]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol binding [GO:0035091]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]
d2emta3_d1euvb___1	Metazoa	Fungi	Chordata	Ascomycota	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]; identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]; protein sumoylation [GO:0016925]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	protein sumoylation [GO:0016925]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]
d2emtb1_d2he7a2__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	axolemma [GO:0030673]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; juxtaparanode region of axon [GO:0044224]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; actin binding [GO:0003779]; structural constituent of cytoskeleton [GO:0005200]; actomyosin structure organization [GO:0031032]; apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; cytoskeletal anchoring at plasma membrane [GO:0007016]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actomyosin structure organization [GO:0031032]; apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; cytoskeletal anchoring at plasma membrane [GO:0007016]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	axolemma [GO:0030673]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; juxtaparanode region of axon [GO:0044224]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; structural constituent of cytoskeleton [GO:0005200]
d2emtb2_d1rrpb___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2emtb3_d1gg3c3__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]
d2emub__d2e17b___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2en5b__d2pcma___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2enba__d3tp6a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2enja1_d1djxb2__1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; centriolar satellite [GO:0034451]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; axon guidance [GO:0007411]; cell chemotaxis [GO:0060326]; Fc-epsilon receptor signaling pathway [GO:0038095]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of T cell apoptotic process [GO:0070233]; peptidyl-serine phosphorylation [GO:0018105]; platelet activation [GO:0030168]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of T-helper 2 cell activation [GO:2000570]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of cell growth [GO:0001558]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of platelet aggregation [GO:0090330]; regulation of transcription, DNA-templated [GO:0006355]; T cell receptor signaling pathway [GO:0050852]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	axon guidance [GO:0007411]; cell chemotaxis [GO:0060326]; Fc-epsilon receptor signaling pathway [GO:0038095]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of T cell apoptotic process [GO:0070233]; peptidyl-serine phosphorylation [GO:0018105]; platelet activation [GO:0030168]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of T-helper 2 cell activation [GO:2000570]; regulation of cell growth [GO:0001558]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of platelet aggregation [GO:0090330]; regulation of transcription, DNA-templated [GO:0006355]; T cell receptor signaling pathway [GO:0050852]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	aggresome [GO:0016235]; centriolar satellite [GO:0034451]; cytosol [GO:0005829]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]
d2enoa1_d1wf7a1__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; integral component of mitochondrial outer membrane [GO:0031307]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic density membrane [GO:0098839]; protein C-terminus binding [GO:0008022]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sprouting angiogenesis [GO:1903671]; protein targeting [GO:0006605]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of endocytosis [GO:0030100]; regulation of Notch signaling pathway [GO:0008593]; Rho protein signal transduction [GO:0007266]	actin cytoskeleton [GO:0015629]; cell projection [GO:0042995]; cell-cell adherens junction [GO:0005913]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; membrane [GO:0016020]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; actinin binding [GO:0042805]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase C binding [GO:0005080]; protein N-terminus binding [GO:0047485]; actin cytoskeleton organization [GO:0030036]; cell growth involved in cardiac muscle cell development [GO:0061049]; heart development [GO:0007507]; muscle structure development [GO:0061061]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of synapse assembly [GO:0051963]	cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sprouting angiogenesis [GO:1903671]; protein targeting [GO:0006605]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of endocytosis [GO:0030100]; regulation of Notch signaling pathway [GO:0008593]; Rho protein signal transduction [GO:0007266]	actin cytoskeleton organization [GO:0030036]; cell growth involved in cardiac muscle cell development [GO:0061049]; heart development [GO:0007507]; muscle structure development [GO:0061061]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of synapse assembly [GO:0051963]	basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; integral component of mitochondrial outer membrane [GO:0031307]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic density membrane [GO:0098839]	actin cytoskeleton [GO:0015629]; cell-cell adherens junction [GO:0005913]; cell projection [GO:0042995]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; membrane [GO:0016020]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; stress fiber [GO:0001725]; Z disc [GO:0030018]	protein C-terminus binding [GO:0008022]	actin binding [GO:0003779]; actinin binding [GO:0042805]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase C binding [GO:0005080]; protein N-terminus binding [GO:0047485]
d2enpa1_d2b3rb1__1	Metazoa	Metazoa	Chordata	Chordata	exocytic vesicle [GO:0070382]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; clathrin binding [GO:0030276]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; positive regulation of dendrite extension [GO:1903861]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192]	clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; 1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091]; autophagosome organization [GO:1905037]; cellular response to starvation [GO:0009267]; endocytosis [GO:0006897]; exocytosis [GO:0006887]; macroautophagy [GO:0016236]; negative regulation of zinc ion transmembrane transport [GO:0071583]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphorylation [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]	calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; positive regulation of dendrite extension [GO:1903861]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192]	autophagosome organization [GO:1905037]; cellular response to starvation [GO:0009267]; endocytosis [GO:0006897]; exocytosis [GO:0006887]; macroautophagy [GO:0016236]; negative regulation of zinc ion transmembrane transport [GO:0071583]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]	exocytic vesicle [GO:0070382]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]	clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; clathrin binding [GO:0030276]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]	1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091]
d2enra__d1gzca___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d2enra__d2a70b2__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; fungal-type vacuole membrane [GO:0000329]; Golgi membrane [GO:0000139]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]; carbohydrate derivative binding [GO:0097367]; mannose binding [GO:0005537]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]		endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]		COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; fungal-type vacuole membrane [GO:0000329]; Golgi membrane [GO:0000139]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate derivative binding [GO:0097367]; mannose binding [GO:0005537]
d2enua__d1bq4b___1		Fungi	Deinococcus-Thermus	Ascomycota	catalytic activity [GO:0003824]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]	phosphoglycerate mutase activity [GO:0004619]
d2enwa__d2p75b___1			Deinococcus-Thermus	Deinococcus-Thermus	catalytic activity [GO:0003824]	catalytic activity [GO:0003824]					catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d2enwb__d2p9ya___1			Deinococcus-Thermus	Deinococcus-Thermus	catalytic activity [GO:0003824]	catalytic activity [GO:0003824]					catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d2enya1_d4k3el1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]		G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]		cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]		ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	
d2eo8b__d1x10d___1			Euryarchaeota	Euryarchaeota	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d2eo8d__d1ioia___1			Euryarchaeota	Euryarchaeota	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d2eo9a1_d1ggcl1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2epfb1_d1rc9a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d2epfd1_d2ddbc1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d2epib__d1s7hd___1			Euryarchaeota	Firmicutes		thiamine binding [GO:0030975]						thiamine binding [GO:0030975]
d2eqba2_d2wjga___1	Fungi		Ascomycota	Euryarchaeota	cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytosol [GO:0005829]; mating projection tip [GO:0043332]; transport vesicle [GO:0030133]; guanyl-nucleotide exchange factor activity [GO:0005085]; identical protein binding [GO:0042802]; phosphatidylinositol-4-phosphate binding [GO:0070273]; autophagy [GO:0006914]; exocytosis [GO:0006887]; protein transport [GO:0015031]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ferrous iron transmembrane transporter activity [GO:0015093]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; iron ion homeostasis [GO:0055072]	autophagy [GO:0006914]; exocytosis [GO:0006887]; protein transport [GO:0015031]	iron ion homeostasis [GO:0055072]	cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytosol [GO:0005829]; mating projection tip [GO:0043332]; transport vesicle [GO:0030133]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	guanyl-nucleotide exchange factor activity [GO:0005085]; identical protein binding [GO:0042802]; phosphatidylinositol-4-phosphate binding [GO:0070273]	ferrous iron transmembrane transporter activity [GO:0015093]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]
d2er0e__d1sp5b___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2erba__d1p28b___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d2erfa__d5ik8a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]; activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]	signaling receptor binding [GO:0005102]
d2erjb1_d1uema1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]; interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	axolemma [GO:0030673]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; cellular response to hormone stimulus [GO:0032870]; central nervous system development [GO:0007417]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; negative regulation of synapse assembly [GO:0051964]; olfactory bulb interneuron development [GO:0021891]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; pulmonary valve morphogenesis [GO:0003184]; retinal ganglion cell axon guidance [GO:0031290]; spinal cord development [GO:0021510]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; cellular response to hormone stimulus [GO:0032870]; central nervous system development [GO:0007417]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; negative regulation of synapse assembly [GO:0051964]; olfactory bulb interneuron development [GO:0021891]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; pulmonary valve morphogenesis [GO:0003184]; retinal ganglion cell axon guidance [GO:0031290]; spinal cord development [GO:0021510]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]	axolemma [GO:0030673]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]	axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]
d2erjg1_d5ecje___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]; interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714]; epithelial cell differentiation [GO:0030855]; intestinal epithelial cell differentiation [GO:0060575]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of neuron projection development [GO:0010976]	activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	epithelial cell differentiation [GO:0030855]; intestinal epithelial cell differentiation [GO:0060575]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of neuron projection development [GO:0010976]	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]	nucleus [GO:0005634]	interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]	DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714]
d2erjg2_d3b83b1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]; interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]		activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]		external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]		interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]	
d2es0a1_d2ihda___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; neuronal cell body membrane [GO:0032809]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; synapse [GO:0045202]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of dopamine receptor signaling pathway [GO:0060159]	G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of dopamine receptor signaling pathway [GO:0060159]	cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; neuronal cell body membrane [GO:0032809]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; synapse [GO:0045202]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]
d2es3a__d3d4kb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]; activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]		calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2esdb__d5ac1d___1		Metazoa	Firmicutes	Chordata	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	cytosol [GO:0005829]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]
d2esdc__d5x5ta___1			Firmicutes	Proteobacteria	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	2,5-dioxovalerate dehydrogenase (NADP+) activity [GO:0047533]; NAD+ binding [GO:0070403]; NADP+ binding [GO:0070401]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; L-arabinose catabolic process to 2-oxoglutarate [GO:0019570]; protein tetramerization [GO:0051262]		L-arabinose catabolic process to 2-oxoglutarate [GO:0019570]; protein tetramerization [GO:0051262]			glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	2,5-dioxovalerate dehydrogenase (NADP+) activity [GO:0047533]; NAD+ binding [GO:0070403]; NADP+ binding [GO:0070401]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]
d2esgc1_d2vufa3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2esla1_d2ka0a___1	Metazoa		Chordata	Thermotogae	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]		protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]		cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]	
d2esla1_d2rmbe___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d2esoa1_d5dfla1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2espa1_d1fzya___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; proteasome binding [GO:0070628]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; vesicle organization [GO:0016050]	cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; vesicle organization [GO:0016050]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; proteasome binding [GO:0070628]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]
d2esva2_d1q94a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2esvb2_d3or7a1__1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	voltage-gated potassium channel complex [GO:0008076]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d2et2a__d1s0ba2__1	Viridiplantae		Streptophyta	Firmicutes	serine-type endopeptidase inhibitor activity [GO:0004867]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	serine-type endopeptidase inhibitor activity [GO:0004867]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d2et7a1_d2cava1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	apoplast [GO:0048046]; cell wall [GO:0005618]; superoxide dismutase complex [GO:1902693]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; nutrient reservoir activity [GO:0045735]; oxalate oxidase activity [GO:0050162]; superoxide dismutase activity [GO:0004784]; cell wall organization [GO:0071555]; oxidation-reduction process [GO:0055114]; protein homooligomerization [GO:0051260]; removal of superoxide radicals [GO:0019430]	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]	cell wall organization [GO:0071555]; oxidation-reduction process [GO:0055114]; protein homooligomerization [GO:0051260]; removal of superoxide radicals [GO:0019430]	protein homotrimerization [GO:0070207]	apoplast [GO:0048046]; cell wall [GO:0005618]; superoxide dismutase complex [GO:1902693]	protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; nutrient reservoir activity [GO:0045735]; oxalate oxidase activity [GO:0050162]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]
d2etna2_d2euld2__1			Deinococcus-Thermus	Deinococcus-Thermus	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; regulation of DNA-templated transcription, elongation [GO:0032784]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA polymerase binding [GO:0070063]; regulation of DNA-templated transcription, elongation [GO:0032784]	regulation of DNA-templated transcription, elongation [GO:0032784]	regulation of DNA-templated transcription, elongation [GO:0032784]			DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA polymerase binding [GO:0070063]
d2etnb2_d2eula2__1			Deinococcus-Thermus	Deinococcus-Thermus	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; regulation of DNA-templated transcription, elongation [GO:0032784]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA polymerase binding [GO:0070063]; regulation of DNA-templated transcription, elongation [GO:0032784]	regulation of DNA-templated transcription, elongation [GO:0032784]	regulation of DNA-templated transcription, elongation [GO:0032784]			DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA polymerase binding [GO:0070063]
d2etnc1_d2p4vd1__1			Deinococcus-Thermus	Proteobacteria	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; regulation of DNA-templated transcription, elongation [GO:0032784]	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; DNA-templated transcription, elongation [GO:0006354]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of mRNA cleavage [GO:0031439]; regulation of DNA-templated transcription, elongation [GO:0032784]	regulation of DNA-templated transcription, elongation [GO:0032784]	DNA-templated transcription, elongation [GO:0006354]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of mRNA cleavage [GO:0031439]; regulation of DNA-templated transcription, elongation [GO:0032784]			DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]
d2etta1_d1xtea___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic vesicle membrane [GO:0030659]; phosphatidylinositol binding [GO:0035091]; protein transport [GO:0015031]	cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; recycling endosome [GO:0055037]; ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091]; potassium channel regulator activity [GO:0015459]; protein serine/threonine kinase activity [GO:0004674]; intracellular signal transduction [GO:0035556]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; peptidyl-serine phosphorylation [GO:0018105]	protein transport [GO:0015031]	intracellular signal transduction [GO:0035556]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; peptidyl-serine phosphorylation [GO:0018105]	cytoplasmic vesicle membrane [GO:0030659]	cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; recycling endosome [GO:0055037]	phosphatidylinositol binding [GO:0035091]	ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091]; potassium channel regulator activity [GO:0015459]; protein serine/threonine kinase activity [GO:0004674]
d2etza1_d1zfpe___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; cytosol [GO:0005829]; plasma membrane raft [GO:0044853]; TCR signalosome [GO:0036398]; cytokine secretion [GO:0050663]; intracellular signal transduction [GO:0035556]; mast cell activation [GO:0045576]; positive regulation of protein kinase activity [GO:0045860]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cytokine secretion [GO:0050663]; intracellular signal transduction [GO:0035556]; mast cell activation [GO:0045576]; positive regulation of protein kinase activity [GO:0045860]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cell-cell junction [GO:0005911]; cytosol [GO:0005829]; plasma membrane raft [GO:0044853]; TCR signalosome [GO:0036398]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]		ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]
d2eu0a1_d4dgxa1__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; cytosol [GO:0005829]; plasma membrane raft [GO:0044853]; TCR signalosome [GO:0036398]; cytokine secretion [GO:0050663]; intracellular signal transduction [GO:0035556]; mast cell activation [GO:0045576]; positive regulation of protein kinase activity [GO:0045860]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]; abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	cytokine secretion [GO:0050663]; intracellular signal transduction [GO:0035556]; mast cell activation [GO:0045576]; positive regulation of protein kinase activity [GO:0045860]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	cell-cell junction [GO:0005911]; cytosol [GO:0005829]; plasma membrane raft [GO:0044853]; TCR signalosome [GO:0036398]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]
d2eu7x__d4qypb___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	vasodilation [GO:0042311]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d2euhb__d4k57a___1			Firmicutes	Deinococcus-Thermus	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]					glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2euhd__d3szab___1		Metazoa	Firmicutes	Chordata	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]
d2eula1_d2p4vf1__1			Deinococcus-Thermus	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA polymerase binding [GO:0070063]; regulation of DNA-templated transcription, elongation [GO:0032784]	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; DNA-templated transcription, elongation [GO:0006354]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of mRNA cleavage [GO:0031439]; regulation of DNA-templated transcription, elongation [GO:0032784]	regulation of DNA-templated transcription, elongation [GO:0032784]	DNA-templated transcription, elongation [GO:0006354]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of mRNA cleavage [GO:0031439]; regulation of DNA-templated transcription, elongation [GO:0032784]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA polymerase binding [GO:0070063]	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]
d2euoa__d3m27a___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2eupa2_d3zcha___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	chloroplast [GO:0009507]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2euqa2_d4czpa___1	Fungi		Ascomycota		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	
d2euta__d3vlib2__1	Fungi		Ascomycota	Euryarchaeota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2ev8a__d1wfga1__1	Metazoa	Metazoa	Chordata	Chordata	centriolar satellite [GO:0034451]; cortical cytoskeleton [GO:0030863]; intracellular [GO:0005622]; membrane [GO:0016020]; plasma membrane [GO:0005886]; stereocilium [GO:0032420]; guanylate kinase activity [GO:0004385]; regulation of neutrophil chemotaxis [GO:0090022]; signal transduction [GO:0007165]	cell junction [GO:0030054]; cell projection [GO:0042995]; cytoskeleton of presynaptic active zone [GO:0048788]; extracellular exosome [GO:0070062]; presynaptic active zone [GO:0048786]; presynaptic active zone cytoplasmic component [GO:0098831]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; Rab GTPase binding [GO:0017137]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic vesicle exocytosis [GO:2000300]; spontaneous neurotransmitter secretion [GO:0061669]	regulation of neutrophil chemotaxis [GO:0090022]; signal transduction [GO:0007165]	calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic vesicle exocytosis [GO:2000300]; spontaneous neurotransmitter secretion [GO:0061669]	centriolar satellite [GO:0034451]; cortical cytoskeleton [GO:0030863]; intracellular [GO:0005622]; membrane [GO:0016020]; plasma membrane [GO:0005886]; stereocilium [GO:0032420]	cell junction [GO:0030054]; cell projection [GO:0042995]; cytoskeleton of presynaptic active zone [GO:0048788]; extracellular exosome [GO:0070062]; presynaptic active zone [GO:0048786]; presynaptic active zone cytoplasmic component [GO:0098831]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]	guanylate kinase activity [GO:0004385]	ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; Rab GTPase binding [GO:0017137]
d2ev8a__d2v90d___1	Metazoa	Metazoa	Chordata	Chordata	centriolar satellite [GO:0034451]; cortical cytoskeleton [GO:0030863]; intracellular [GO:0005622]; membrane [GO:0016020]; plasma membrane [GO:0005886]; stereocilium [GO:0032420]; guanylate kinase activity [GO:0004385]; regulation of neutrophil chemotaxis [GO:0090022]; signal transduction [GO:0007165]	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytosol [GO:0005829]; subapical complex [GO:0035003]; guanylate cyclase inhibitor activity [GO:0030251]; ion channel inhibitor activity [GO:0008200]; protein C-terminus binding [GO:0008022]; ubiquitin-specific protease binding [GO:1990381]; ion transport [GO:0006811]; negative regulation of cGMP-mediated signaling [GO:0010754]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to toxic substance [GO:0009636]; water transport [GO:0006833]	regulation of neutrophil chemotaxis [GO:0090022]; signal transduction [GO:0007165]	ion transport [GO:0006811]; negative regulation of cGMP-mediated signaling [GO:0010754]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to toxic substance [GO:0009636]; water transport [GO:0006833]	centriolar satellite [GO:0034451]; cortical cytoskeleton [GO:0030863]; intracellular [GO:0005622]; membrane [GO:0016020]; plasma membrane [GO:0005886]; stereocilium [GO:0032420]	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytosol [GO:0005829]; subapical complex [GO:0035003]	guanylate kinase activity [GO:0004385]	guanylate cyclase inhibitor activity [GO:0030251]; ion channel inhibitor activity [GO:0008200]; protein C-terminus binding [GO:0008022]; ubiquitin-specific protease binding [GO:1990381]
d2evca__d2bwwa2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	protein initiator methionine removal [GO:0070084]		cytosol [GO:0005829]	cytosol [GO:0005829]	ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]	aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]
d2evna1_d3wr7a___1	Viridiplantae		Streptophyta	Proteobacteria	peroxisome [GO:0005777]; histone acetyltransferase activity [GO:0004402]	N-acetyltransferase activity [GO:0008080]			peroxisome [GO:0005777]		histone acetyltransferase activity [GO:0004402]	N-acetyltransferase activity [GO:0008080]
d2evob__d4fo8a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]
d2evpa__d1yhul___1	Metazoa	Metazoa	Chordata	Annelida	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2evxa2_d4xfha___1	Viridiplantae	Metazoa	Streptophyta	Chordata	metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]		cysteine metabolic process [GO:0006534]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d2ew9a1_d1cc7a___1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; protein maturation by copper ion transfer [GO:0015680]; response to copper ion [GO:0046688]; sequestering of calcium ion [GO:0051208]	cell [GO:0005623]; cytosol [GO:0005829]; copper chaperone activity [GO:0016531]; cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; protein maturation by copper ion transfer [GO:0015680]; response to copper ion [GO:0046688]; sequestering of calcium ion [GO:0051208]	cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]	cell [GO:0005623]; cytosol [GO:0005829]	ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]	copper chaperone activity [GO:0016531]
d2ewba2_d3uelb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	chromatin [GO:0000785]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; poly(ADP-ribose) glycohydrolase activity [GO:0004649]; ATP generation from poly-ADP-D-ribose [GO:1990966]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-sugar metabolic process [GO:0009225]; positive regulation of DNA repair [GO:0045739]; regulation of DNA repair [GO:0006282]		ATP generation from poly-ADP-D-ribose [GO:1990966]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-sugar metabolic process [GO:0009225]; positive regulation of DNA repair [GO:0045739]; regulation of DNA repair [GO:0006282]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	chromatin [GO:0000785]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]	aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	chromatin binding [GO:0003682]; poly(ADP-ribose) glycohydrolase activity [GO:0004649]
d2ewdb4_d3wswc2__1				Firmicutes		cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d2ewga__d3wchd___1		Metazoa		Chordata	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d2ewmb1_d1u3ua2__1		Metazoa	Proteobacteria	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; anaerobic ethylbenzene catabolic process [GO:0010130]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	anaerobic ethylbenzene catabolic process [GO:0010130]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d2ewnb3_d2dz9b1__1			Proteobacteria	Euryarchaeota	transcriptional repressor complex [GO:0017053]; ATP binding [GO:0005524]; bacterial-type RNA polymerase regulatory region sequence-specific DNA binding [GO:0000984]; biotin binding [GO:0009374]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; DNA binding [GO:0003677]; protein homodimerization activity [GO:0042803]; biotin biosynthetic process [GO:0009102]; biotin metabolic process [GO:0006768]; protein biotinylation [GO:0009305]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	biotin biosynthetic process [GO:0009102]; biotin metabolic process [GO:0006768]; protein biotinylation [GO:0009305]; regulation of transcription, DNA-templated [GO:0006355]	cellular protein modification process [GO:0006464]	transcriptional repressor complex [GO:0017053]		ATP binding [GO:0005524]; bacterial-type RNA polymerase regulatory region sequence-specific DNA binding [GO:0000984]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; biotin binding [GO:0009374]; DNA binding [GO:0003677]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d2ewua__d1i77a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	anaerobic respiration [GO:0009061]		periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2ex0a1_d6gpba___1		Metazoa	Proteobacteria	Chordata	transferase activity, transferring glycosyl groups [GO:0016757]	skeletal muscle myofibril [GO:0098723]; glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]; glycogen metabolic process [GO:0005977]		glycogen metabolic process [GO:0005977]		skeletal muscle myofibril [GO:0098723]	transferase activity, transferring glycosyl groups [GO:0016757]	glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]
d2ex3e1_d4huea___1				Firmicutes	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]			cytoplasm [GO:0005737]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d2ex3g1_d2dtuc1__1					DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]			DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2exga2_d2zlec1__1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; pore complex [GO:0046930]; tight junction [GO:0070160]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; protein C-terminus binding [GO:0008022]; Ras GTPase binding [GO:0017016]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of protein localization to plasma membrane [GO:0061951]; negative regulation of cell migration [GO:0030336]; pore complex assembly [GO:0046931]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of protein localization to plasma membrane [GO:0061951]; negative regulation of cell migration [GO:0030336]; pore complex assembly [GO:0046931]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; pore complex [GO:0046930]; tight junction [GO:0070160]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; protein C-terminus binding [GO:0008022]; Ras GTPase binding [GO:0017016]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2exhb1_d3vznb___1			Firmicutes	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d2exhb2_d4udid___1			Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	
d2exhc1_d1refa1__1		Fungi	Firmicutes	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d2exia2_d4udgd___1			Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	
d2exib2_d3om4d___1			Firmicutes	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]	carbohydrate metabolic process [GO:0005975]	carbohydrate utilization [GO:0009758]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]
d2exic1_d1uzzd___1		Viridiplantae	Firmicutes	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2exid2_d4udkf___1			Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	
d2exjb2_d1w2tf2__1			Firmicutes	Thermotogae	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	beta-fructofuranosidase activity [GO:0004564]
d2exjd2_d1utwe1__1			Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	
d2exka1_d1ioab___1		Viridiplantae	Firmicutes	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; nutrient reservoir activity [GO:0045735]; toxin activity [GO:0090729]; defense response [GO:0006952]	carbohydrate metabolic process [GO:0005975]	defense response [GO:0006952]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; nutrient reservoir activity [GO:0045735]; toxin activity [GO:0090729]
d2exka2_d4udja___1			Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	
d2exkb2_d1y9ma2__1		Fungi	Firmicutes	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; fructan beta-fructosidase activity [GO:0051669]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	fructan beta-fructosidase activity [GO:0051669]
d2exkc2_d4udib___1			Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	
d2exkd2_d1yifc2__1			Firmicutes	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]; xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]		plasma membrane [GO:0005886]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d2exma__d5mqve___1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; tau-protein kinase activity [GO:0050321]; ciliary basal body-plasma membrane docking [GO:0097711]; circadian regulation of gene expression [GO:0032922]; COPII vesicle coating [GO:0048208]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi organization [GO:0007030]; microtubule nucleation [GO:0007020]; non-motile cilium assembly [GO:1905515]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation [GO:1905426]; protein localization to centrosome [GO:0071539]; protein localization to cilium [GO:0061512]; protein localization to Golgi apparatus [GO:0034067]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	ciliary basal body-plasma membrane docking [GO:0097711]; circadian regulation of gene expression [GO:0032922]; COPII vesicle coating [GO:0048208]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi organization [GO:0007030]; microtubule nucleation [GO:0007020]; non-motile cilium assembly [GO:1905515]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation [GO:1905426]; protein localization to centrosome [GO:0071539]; protein localization to cilium [GO:0061512]; protein localization to Golgi apparatus [GO:0034067]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; spindle [GO:0005819]; spindle microtubule [GO:0005876]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; tau-protein kinase activity [GO:0050321]
d2exoa__d1jz6b5__1			Actinobacteria	Proteobacteria	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2exvc__d3zowa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2exwd1_d5hd8f2__1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d2exyd2_d5vf2a1__1			Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	
d2exyf2_d5f3hb1__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]; cell development [GO:0048468]; cellular response to dexamethasone stimulus [GO:0071549]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of kinase activity [GO:0033673]; negative regulation of muscle hypertrophy [GO:0014741]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast proliferation [GO:2000818]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; negative regulation of skeletal muscle tissue growth [GO:0048632]; ovulation cycle process [GO:0022602]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; response to electrical stimulus [GO:0051602]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to gravity [GO:0009629]; response to heat [GO:0009408]; response to muscle activity [GO:0014850]; response to testosterone [GO:0033574]; skeletal muscle atrophy [GO:0014732]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cell development [GO:0048468]; cellular response to dexamethasone stimulus [GO:0071549]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of kinase activity [GO:0033673]; negative regulation of muscle hypertrophy [GO:0014741]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast proliferation [GO:2000818]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; negative regulation of skeletal muscle tissue growth [GO:0048632]; ovulation cycle process [GO:0022602]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; response to electrical stimulus [GO:0051602]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to gravity [GO:0009629]; response to heat [GO:0009408]; response to muscle activity [GO:0014850]; response to testosterone [GO:0033574]; skeletal muscle atrophy [GO:0014732]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]
d2ey2a__d2f0da___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2eyfa__d1nsns___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2eyia2_d1dxxd2__1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; pseudopodium [GO:0031143]; ruffle [GO:0001726]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; double-stranded RNA binding [GO:0003725]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; structural constituent of postsynapse [GO:0099186]; vinculin binding [GO:0017166]; actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; focal adhesion assembly [GO:0048041]; negative regulation of cellular component movement [GO:0051271]; platelet degranulation [GO:0002576]; platelet formation [GO:0030220]; platelet morphogenesis [GO:0036344]; regulation of apoptotic process [GO:0042981]	cell [GO:0005623]; cell surface [GO:0009986]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]; actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein localization [GO:0034613]; cellular protein-containing complex assembly [GO:0034622]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; focal adhesion assembly [GO:0048041]; negative regulation of cellular component movement [GO:0051271]; platelet degranulation [GO:0002576]; platelet formation [GO:0030220]; platelet morphogenesis [GO:0036344]; regulation of apoptotic process [GO:0042981]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein-containing complex assembly [GO:0034622]; cellular protein localization [GO:0034613]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	brush border [GO:0005903]; cell-cell junction [GO:0005911]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; pseudopodium [GO:0031143]; ruffle [GO:0001726]; stress fiber [GO:0001725]; Z disc [GO:0030018]	cell [GO:0005623]; cell-substrate junction [GO:0030055]; cell surface [GO:0009986]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; double-stranded RNA binding [GO:0003725]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; structural constituent of postsynapse [GO:0099186]; vinculin binding [GO:0017166]	actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]
d2eyla__d3lx0a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2eyma__d1ey7a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2eyna2_d3hora2__1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; pseudopodium [GO:0031143]; ruffle [GO:0001726]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; double-stranded RNA binding [GO:0003725]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; structural constituent of postsynapse [GO:0099186]; vinculin binding [GO:0017166]; actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; focal adhesion assembly [GO:0048041]; negative regulation of cellular component movement [GO:0051271]; platelet degranulation [GO:0002576]; platelet formation [GO:0030220]; platelet morphogenesis [GO:0036344]; regulation of apoptotic process [GO:0042981]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; focal adhesion assembly [GO:0048041]; negative regulation of cellular component movement [GO:0051271]; platelet degranulation [GO:0002576]; platelet formation [GO:0030220]; platelet morphogenesis [GO:0036344]; regulation of apoptotic process [GO:0042981]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	brush border [GO:0005903]; cell-cell junction [GO:0005911]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; pseudopodium [GO:0031143]; ruffle [GO:0001726]; stress fiber [GO:0001725]; Z disc [GO:0030018]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; double-stranded RNA binding [GO:0003725]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; structural constituent of postsynapse [GO:0099186]; vinculin binding [GO:0017166]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d2eyqa5_d2eyqa4__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	cytosol [GO:0005829]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]
d2eyqb2_d2fzla1__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]		cytosol [GO:0005829]		ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]
d2eyqb3_d1s2ma1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytoplasmic stress granule [GO:0010494]; P-body [GO:0000932]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of translation [GO:0017148]; negative regulation of translational elongation [GO:0045900]; regulation of cytoplasmic mRNA processing body assembly [GO:0010603]; stress granule assembly [GO:0034063]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of translation [GO:0017148]; negative regulation of translational elongation [GO:0045900]; regulation of cytoplasmic mRNA processing body assembly [GO:0010603]; stress granule assembly [GO:0034063]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytoplasmic stress granule [GO:0010494]; P-body [GO:0000932]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]
d2eyrb2_d3w2dl2__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d2eysb1_d2r23a1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2eyta1_d2iqal2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	metal ion binding [GO:0046872]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]			metal ion binding [GO:0046872]
d2eytc1_d1nl0l1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]
d2eytd2_d3ijha1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]			
d2eyva2_d3eaza___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; cytoskeletal protein binding [GO:0008092]; ephrin receptor binding [GO:0046875]; insulin-like growth factor receptor binding [GO:0005159]; phosphotyrosine residue binding [GO:0001784]; protein phosphorylated amino acid binding [GO:0045309]; protein self-association [GO:0043621]; protein tyrosine kinase binding [GO:1990782]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; activation of GTPase activity [GO:0090630]; activation of MAPKK activity [GO:0000186]; cell chemotaxis [GO:0060326]; cellular response to endothelin [GO:1990859]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to nitric oxide [GO:0071732]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cerebellar neuron development [GO:0098749]; cerebral cortex development [GO:0021987]; cytokine-mediated signaling pathway [GO:0019221]; dendrite development [GO:0016358]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; helper T cell diapedesis [GO:0035685]; hippocampus development [GO:0021766]; lipid metabolic process [GO:0006629]; negative regulation of cell motility [GO:2000146]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of wound healing [GO:0061045]; neuron migration [GO:0001764]; positive regulation of cell growth [GO:0030307]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; reelin-mediated signaling pathway [GO:0038026]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of GTPase activity [GO:0043087]; regulation of protein binding [GO:0043393]; regulation of Rac protein signal transduction [GO:0035020]; regulation of signal transduction [GO:0009966]; regulation of T cell migration [GO:2000404]; regulation of transcription by RNA polymerase II [GO:0006357]; response to cholecystokinin [GO:0061847]; response to hepatocyte growth factor [GO:0035728]; response to hydrogen peroxide [GO:0042542]; response to yeast [GO:0001878]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	activation of GTPase activity [GO:0090630]; activation of MAPKK activity [GO:0000186]; cell chemotaxis [GO:0060326]; cellular response to endothelin [GO:1990859]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to nitric oxide [GO:0071732]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cerebellar neuron development [GO:0098749]; cerebral cortex development [GO:0021987]; cytokine-mediated signaling pathway [GO:0019221]; dendrite development [GO:0016358]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; helper T cell diapedesis [GO:0035685]; hippocampus development [GO:0021766]; lipid metabolic process [GO:0006629]; negative regulation of cell motility [GO:2000146]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of wound healing [GO:0061045]; neuron migration [GO:0001764]; positive regulation of cell growth [GO:0030307]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; reelin-mediated signaling pathway [GO:0038026]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of GTPase activity [GO:0043087]; regulation of protein binding [GO:0043393]; regulation of Rac protein signal transduction [GO:0035020]; regulation of signal transduction [GO:0009966]; regulation of T cell migration [GO:2000404]; regulation of transcription by RNA polymerase II [GO:0006357]; response to cholecystokinin [GO:0061847]; response to hepatocyte growth factor [GO:0035728]; response to hydrogen peroxide [GO:0042542]; response to yeast [GO:0001878]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoskeletal protein binding [GO:0008092]; ephrin receptor binding [GO:0046875]; insulin-like growth factor receptor binding [GO:0005159]; phosphotyrosine residue binding [GO:0001784]; protein phosphorylated amino acid binding [GO:0045309]; protein self-association [GO:0043621]; protein tyrosine kinase binding [GO:1990782]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]
d2ez0d1_d1lo0x1__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ez0d2_d4bjlb2__1			Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	
d2ez0d2_d5k9qi1__1			Proteobacteria	Negarnaviricota	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	host cell surface receptor binding [GO:0046789]
d2ez0f1_d3q6fa2__1			Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	
d2ez0f2_d3ilpb___1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ez4a3_d1zpde3__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2ez4b1_d5d7qb___1		Metazoa	Firmicutes	Chordata	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	centriole [GO:0005814]; centrosome [GO:0005813]; chromatin silencing complex [GO:0005677]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glial cell projection [GO:0097386]; growth cone [GO:0030426]; juxtaparanode region of axon [GO:0044224]; lateral loop [GO:0043219]; meiotic spindle [GO:0072687]; microtubule [GO:0005874]; midbody [GO:0030496]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; myelin sheath [GO:0043209]; nuclear heterochromatin [GO:0005720]; nucleolus [GO:0005730]; nucleus [GO:0005634]; paranodal junction [GO:0033010]; paranode region of axon [GO:0033270]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; Schmidt-Lanterman incisure [GO:0043220]; spindle [GO:0005819]; chromatin binding [GO:0003682]; histone acetyltransferase binding [GO:0035035]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone deacetylase activity (H4-K16 specific) [GO:0046970]; NAD-dependent protein deacetylase activity [GO:0034979]; protein deacetylase activity [GO:0033558]; transcription factor binding [GO:0008134]; tubulin deacetylase activity [GO:0042903]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; cell division [GO:0051301]; cellular lipid catabolic process [GO:0044242]; cellular response to caloric restriction [GO:0061433]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to oxidative stress [GO:0034599]; chromatin silencing [GO:0006342]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at telomere [GO:0006348]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; innate immune response [GO:0045087]; meiotic cell cycle [GO:0051321]; myelination in peripheral nervous system [GO:0022011]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine deacetylation [GO:0034983]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of cell division [GO:0051781]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]; protein kinase B signaling [GO:0043491]; regulation of cell cycle [GO:0051726]; regulation of exit from mitosis [GO:0007096]; regulation of myelination [GO:0031641]; regulation of phosphorylation [GO:0042325]; response to redox state [GO:0051775]; substantia nigra development [GO:0021762]; tubulin deacetylation [GO:0090042]		autophagy [GO:0006914]; cell division [GO:0051301]; cellular lipid catabolic process [GO:0044242]; cellular response to caloric restriction [GO:0061433]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to oxidative stress [GO:0034599]; chromatin silencing [GO:0006342]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at telomere [GO:0006348]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; innate immune response [GO:0045087]; meiotic cell cycle [GO:0051321]; myelination in peripheral nervous system [GO:0022011]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; peptidyl-lysine deacetylation [GO:0034983]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of cell division [GO:0051781]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]; protein kinase B signaling [GO:0043491]; regulation of cell cycle [GO:0051726]; regulation of exit from mitosis [GO:0007096]; regulation of myelination [GO:0031641]; regulation of phosphorylation [GO:0042325]; response to redox state [GO:0051775]; substantia nigra development [GO:0021762]; tubulin deacetylation [GO:0090042]		centriole [GO:0005814]; centrosome [GO:0005813]; chromatin silencing complex [GO:0005677]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glial cell projection [GO:0097386]; growth cone [GO:0030426]; juxtaparanode region of axon [GO:0044224]; lateral loop [GO:0043219]; meiotic spindle [GO:0072687]; microtubule [GO:0005874]; midbody [GO:0030496]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; myelin sheath [GO:0043209]; nuclear heterochromatin [GO:0005720]; nucleolus [GO:0005730]; nucleus [GO:0005634]; paranodal junction [GO:0033010]; paranode region of axon [GO:0033270]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; Schmidt-Lanterman incisure [GO:0043220]; spindle [GO:0005819]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	chromatin binding [GO:0003682]; histone acetyltransferase binding [GO:0035035]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone deacetylase activity (H4-K16 specific) [GO:0046970]; NAD-dependent protein deacetylase activity [GO:0034979]; protein deacetylase activity [GO:0033558]; transcription factor binding [GO:0008134]; tubulin deacetylase activity [GO:0042903]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270]
d2ez8a2_d1jsca2__1		Fungi	Firmicutes	Ascomycota	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2ez8a3_d1gpub1__1		Fungi	Firmicutes	Ascomycota	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]		pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d2ez8a3_d2ez8a2__1			Firmicutes	Firmicutes	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d2ez8b2_d1qgda2__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d2ez8b3_d4jufb1__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2ezta1_d2wvav2__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2ezta2_d4mppa3__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2eztb2_d1upbb3__1			Firmicutes	Actinobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]
d2eztb2_d2w93c1__1		Fungi	Firmicutes	Ascomycota	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2eztb3_d1w85h1__1			Firmicutes	Firmicutes	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]			magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2eztb3_d5tmab1__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2ezua1_d1bfda1__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2ezua1_d1djlb___1		Metazoa	Firmicutes	Chordata	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; NAD binding [GO:0051287]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD(P)+ transhydrogenase activity [GO:0008746]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular oxidant detoxification [GO:0098869]; NADPH regeneration [GO:0006740]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein phosphorylation [GO:0001933]; oxidation-reduction process [GO:0055114]; oxygen homeostasis [GO:0032364]; positive regulation of hydrogen peroxide catabolic process [GO:1903285]; positive regulation of mitochondrial membrane potential [GO:0010918]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593]; response to vitamin [GO:0033273]; tricarboxylic acid cycle [GO:0006099]		cell redox homeostasis [GO:0045454]; cellular oxidant detoxification [GO:0098869]; NADPH regeneration [GO:0006740]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein phosphorylation [GO:0001933]; oxidation-reduction process [GO:0055114]; oxygen homeostasis [GO:0032364]; positive regulation of hydrogen peroxide catabolic process [GO:1903285]; positive regulation of mitochondrial membrane potential [GO:0010918]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593]; response to vitamin [GO:0033273]; tricarboxylic acid cycle [GO:0006099]		cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD(P)+ transhydrogenase activity [GO:0008746]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2ezua2_d5hgxa2__1		Fungi	Firmicutes	Ascomycota	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]					magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d2ezub2_d2c3mb2__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]		electron transport chain [GO:0022900]		cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d2f08a__d4al8c___1	Metazoa		Arthropoda		extracellular region [GO:0005576]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2f0cb1_d2j1ke___1		Metazoa		Chordata	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	virus tail, baseplate [GO:0098025]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2f0cc1_d4k6wa___1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]	viral capsid [GO:0019028]		metal ion binding [GO:0046872]
d2f0ha__d1stya___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2f0ja__d4id6a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2f0qa__d4laaa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2f0ya__d1jcra___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]; protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]; protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d2f16a__d4qwjz___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2f16c__d3s8rb___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	periplasmic space [GO:0042597]; glutaryl-7-aminocephalosporanic-acid acylase activity [GO:0033968]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	periplasmic space [GO:0042597]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	glutaryl-7-aminocephalosporanic-acid acylase activity [GO:0033968]
d2f16c__d4qv3u___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2f16l__d3l5qh___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	
d2f16m__d5l69t___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2f16w__d5bouv___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2f16x__d5lexm___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2f19h1_d3upch___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2f19h2_d4zdhb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2f19l1_d4nbxb___1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	transferase activity, transferring glycosyl groups [GO:0016757]; pathogenesis [GO:0009405]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	transferase activity, transferring glycosyl groups [GO:0016757]
d2f19l2_d4fp8l1__1	Metazoa		Chordata	Negarnaviricota	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	host cell surface receptor binding [GO:0046789]
d2f1da1_d1i95e1__1	Viridiplantae		Streptophyta	Deinococcus-Thermus	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	histidine biosynthetic process [GO:0000105]	translation [GO:0006412]	chloroplast [GO:0009507]	ribosome [GO:0005840]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2f1db1_d4mu3a1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2f1dc1_d4qnkh2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2f1de1_d1i97i___1	Viridiplantae		Streptophyta	Deinococcus-Thermus	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	histidine biosynthetic process [GO:0000105]	translation [GO:0006412]	chloroplast [GO:0009507]	ribosome [GO:0005840]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2f1df1_d2z4ke1__1	Viridiplantae		Streptophyta		chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]		histidine biosynthetic process [GO:0000105]		chloroplast [GO:0009507]		imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]	
d2f1dg1_d4qnkg2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2f1dh1_d1rhyb2__1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]		imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]
d2f1dn1_d2f1dj2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2f1do1_d1yh8a2__1	Viridiplantae		Streptophyta	Aquificae	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	histidine biosynthetic process [GO:0000105]	lipid A biosynthetic process [GO:0009245]	chloroplast [GO:0009507]		imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d2f1do1_d4qnja2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2f1dp2_d4qnke2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	histidine biosynthetic process [GO:0000105]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2f1fb1_d3qsij___1			Proteobacteria	Proteobacteria	acetolactate synthase complex [GO:0005948]; cytosol [GO:0005829]; acetolactate synthase activity [GO:0003984]; acetolactate synthase regulator activity [GO:1990610]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	acetolactate synthase complex [GO:0005948]; cytosol [GO:0005829]	protein-DNA complex [GO:0032993]	acetolactate synthase activity [GO:0003984]; acetolactate synthase regulator activity [GO:1990610]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2f1na1_d3g3ca___1			Proteobacteria	Euryarchaeota	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; toxin activity [GO:0090729]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]		DNA repair [GO:0006281]	extracellular region [GO:0005576]		endonuclease activity [GO:0004519]; toxin activity [GO:0090729]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d2f1oc__d2fvxa___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2f1od__d1ykga1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]
d2f1oe__d3qfrb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d2f1og__d2w5ua___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	FMN binding [GO:0010181]; oxidation-reduction process [GO:0055114]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	FMN binding [GO:0010181]
d2f1oh__d3nhua___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d2f21a2_d4c02b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	calcium channel complex [GO:0034704]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018]; calcium channel inhibitor activity [GO:0019855]; cyclic nucleotide binding [GO:0030551]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; signaling receptor binding [GO:0005102]; 'de novo' protein folding [GO:0006458]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; chaperone-mediated protein folding [GO:0061077]; insulin secretion [GO:0030073]; ion transmembrane transport [GO:0034220]; negative regulation of heart rate [GO:0010459]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of release of sequestered calcium ion into cytosol [GO:0051280]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neuronal action potential propagation [GO:0019227]; positive regulation of axon regeneration [GO:0048680]; positive regulation of sequestering of calcium ion [GO:0051284]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; release of sequestered calcium ion into cytosol [GO:0051209]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to redox state [GO:0051775]; response to vitamin E [GO:0033197]; smooth muscle contraction [GO:0006939]; T cell proliferation [GO:0042098]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	'de novo' protein folding [GO:0006458]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; chaperone-mediated protein folding [GO:0061077]; insulin secretion [GO:0030073]; ion transmembrane transport [GO:0034220]; negative regulation of heart rate [GO:0010459]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of release of sequestered calcium ion into cytosol [GO:0051280]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neuronal action potential propagation [GO:0019227]; positive regulation of axon regeneration [GO:0048680]; positive regulation of sequestering of calcium ion [GO:0051284]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; release of sequestered calcium ion into cytosol [GO:0051209]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to redox state [GO:0051775]; response to vitamin E [GO:0033197]; smooth muscle contraction [GO:0006939]; T cell proliferation [GO:0042098]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	calcium channel complex [GO:0034704]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	calcium channel inhibitor activity [GO:0019855]; cyclic nucleotide binding [GO:0030551]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; signaling receptor binding [GO:0005102]
d2f23b1_d2p4vc1__1			Deinococcus-Thermus	Proteobacteria	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; regulation of DNA-templated transcription, elongation [GO:0032784]	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; DNA-templated transcription, elongation [GO:0006354]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of mRNA cleavage [GO:0031439]; regulation of DNA-templated transcription, elongation [GO:0032784]	regulation of DNA-templated transcription, elongation [GO:0032784]	DNA-templated transcription, elongation [GO:0006354]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of mRNA cleavage [GO:0031439]; regulation of DNA-templated transcription, elongation [GO:0032784]			DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]
d2f2ab2_d1crkb2__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]; regulation of translational fidelity [GO:0006450]; translation [GO:0006412]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; phosphocreatine biosynthetic process [GO:0046314]	regulation of translational fidelity [GO:0006450]; translation [GO:0006412]	phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d2f2fa1_d3ca1a1__1		Viridiplantae	Proteobacteria	Streptophyta	negative regulation by symbiont of host cell cycle [GO:0044072]; pathogenesis [GO:0009405]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	negative regulation by symbiont of host cell cycle [GO:0044072]; pathogenesis [GO:0009405]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]				carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2f2fb1_d3i41a___1			Proteobacteria	Firmicutes	negative regulation by symbiont of host cell cycle [GO:0044072]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081]	negative regulation by symbiont of host cell cycle [GO:0044072]; pathogenesis [GO:0009405]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081]
d2f2fd__d4qd2i2__1		Metazoa	Proteobacteria	Chordata	negative regulation by symbiont of host cell cycle [GO:0044072]; pathogenesis [GO:0009405]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	negative regulation by symbiont of host cell cycle [GO:0044072]; pathogenesis [GO:0009405]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]		actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]		alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d2f2fe__d3ga6a___1			Proteobacteria	Euryarchaeota	negative regulation by symbiont of host cell cycle [GO:0044072]; pathogenesis [GO:0009405]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	negative regulation by symbiont of host cell cycle [GO:0044072]; pathogenesis [GO:0009405]	DNA repair [GO:0006281]				DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d2f2ha4_d3emza___1			Proteobacteria	Firmicutes	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]		cytoplasm [GO:0005737]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	endo-1,4-beta-xylanase activity [GO:0031176]
d2f2hb3_d1wzlb2__1			Proteobacteria	Firmicutes	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2f2hd1_d3lppa4__1		Metazoa	Proteobacteria	Chordata	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]
d2f2hf2_d3dyma5__1			Proteobacteria	Proteobacteria	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2f2ka__d2c91c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; phenanthrene-9,10-epoxide hydrolase activity [GO:0019119]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; phenanthrene-9,10-epoxide hydrolase activity [GO:0019119]
d2f2lx1_d4oppa___1	Metazoa	Metazoa	Arthropoda	Chordata	apicolateral plasma membrane [GO:0016327]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; lipopolysaccharide receptor activity [GO:0001875]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; peptidoglycan receptor activity [GO:0016019]; zinc ion binding [GO:0008270]; antibacterial humoral response [GO:0019731]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of natural killer cell differentiation involved in immune response [GO:0032827]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; regulation of humoral immune response [GO:0002920]; regulation of melanization defense response [GO:0035007]; regulation of synaptic plasticity [GO:0048167]; response to bacterium [GO:0009617]	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	antibacterial humoral response [GO:0019731]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of natural killer cell differentiation involved in immune response [GO:0032827]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; regulation of humoral immune response [GO:0002920]; regulation of melanization defense response [GO:0035007]; regulation of synaptic plasticity [GO:0048167]; response to bacterium [GO:0009617]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	apicolateral plasma membrane [GO:0016327]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; presynapse [GO:0098793]	extracellular region [GO:0005576]	lipopolysaccharide receptor activity [GO:0001875]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; peptidoglycan receptor activity [GO:0016019]; zinc ion binding [GO:0008270]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]
d2f30a__d1l57a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2f32a__d1jj0a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2f32a__d232la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2f36a__d5h8sc1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2f36b__d4yb5b1__1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	histidine biosynthetic process [GO:0000105]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d2f36d__d2v93a___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d2f3ma2_d4gssb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2f3mb1_d3uapa2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	glutathione transferase activity [GO:0004364]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d2f3mb2_d1guhd2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2f3mb2_d1ti1a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d2f3mc1_d3vwxd2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	glutathione transferase activity [GO:0004364]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d2f3mc2_d1o85a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	cell [GO:0005623]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	
d2f3me1_d1oe8b1__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	glutathione transferase activity [GO:0004364]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d2f3me2_d5g5ab1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; 2,4,6-trinitrotoluene catabolic process [GO:0046256]; glutathione metabolic process [GO:0006749]; toxin catabolic process [GO:0009407]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	2,4,6-trinitrotoluene catabolic process [GO:0046256]; glutathione metabolic process [GO:0006749]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d2f3td__d4klnf3__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; guanylate kinase activity [GO:0004385]; identical protein binding [GO:0042802]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	cytosol [GO:0005829]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATP binding [GO:0005524]; guanylate kinase activity [GO:0004385]; identical protein binding [GO:0042802]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d2f3ya__d1m31b___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d2f43b2_d2jj1l1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial envelope [GO:0005740]; mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP biosynthetic process [GO:0006754]; ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; cellular response to nitric oxide [GO:0071732]; oxidative phosphorylation [GO:0006119]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP biosynthetic process [GO:0006754]; ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; cellular response to nitric oxide [GO:0071732]; oxidative phosphorylation [GO:0006119]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial envelope [GO:0005740]; mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2f43b2_d5hkka1__1	Metazoa		Chordata	Firmicutes	mitochondrial envelope [GO:0005740]; mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP biosynthetic process [GO:0006754]; ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; cellular response to nitric oxide [GO:0071732]; oxidative phosphorylation [GO:0006119]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP biosynthetic process [GO:0006754]; ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; cellular response to nitric oxide [GO:0071732]; oxidative phosphorylation [GO:0006119]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial envelope [GO:0005740]; mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2f44c__d2eana1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell junction [GO:0030054]; ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; neuron projection [GO:0043005]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; actin binding [GO:0003779]; GKAP/Homer scaffold activity [GO:0030160]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; protein C-terminus binding [GO:0008022]; protein self-association [GO:0043621]; receptor signaling complex adaptor activity [GO:0030159]; scaffold protein binding [GO:0097110]; SH3 domain binding [GO:0017124]; structural constituent of postsynaptic density [GO:0098919]; zinc ion binding [GO:0008270]; AMPA glutamate receptor clustering [GO:0097113]; brain morphogenesis [GO:0048854]; dendritic spine morphogenesis [GO:0060997]; guanylate kinase-associated protein clustering [GO:0097117]; learning [GO:0007612]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; maintenance of postsynaptic density structure [GO:0099562]; MAPK cascade [GO:0000165]; memory [GO:0007613]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of cell volume [GO:0045794]; neuromuscular process controlling balance [GO:0050885]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of glutamate receptor signaling pathway [GO:1900451]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of synapse structural plasticity [GO:0051835]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density assembly [GO:0097107]; protein complex oligomerization [GO:0051259]; regulation of AMPA receptor activity [GO:2000311]; regulation of behavioral fear response [GO:2000822]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of grooming behavior [GO:2000821]; regulation of long-term synaptic depression [GO:1900452]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of synapse organization [GO:0050807]; social behavior [GO:0035176]; striatal medium spiny neuron differentiation [GO:0021773]; synapse assembly [GO:0007416]; synaptic growth at neuromuscular junction [GO:0051124]; vocalization behavior [GO:0071625]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; identical protein binding [GO:0042802]; postsynapse organization [GO:0099173]; regulation of signal transduction [GO:0009966]	AMPA glutamate receptor clustering [GO:0097113]; brain morphogenesis [GO:0048854]; dendritic spine morphogenesis [GO:0060997]; guanylate kinase-associated protein clustering [GO:0097117]; learning [GO:0007612]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; maintenance of postsynaptic density structure [GO:0099562]; MAPK cascade [GO:0000165]; memory [GO:0007613]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of cell volume [GO:0045794]; neuromuscular process controlling balance [GO:0050885]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of glutamate receptor signaling pathway [GO:1900451]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of synapse structural plasticity [GO:0051835]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density assembly [GO:0097107]; protein complex oligomerization [GO:0051259]; regulation of AMPA receptor activity [GO:2000311]; regulation of behavioral fear response [GO:2000822]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of grooming behavior [GO:2000821]; regulation of long-term synaptic depression [GO:1900452]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of synapse organization [GO:0050807]; social behavior [GO:0035176]; striatal medium spiny neuron differentiation [GO:0021773]; synapse assembly [GO:0007416]; synaptic growth at neuromuscular junction [GO:0051124]; vocalization behavior [GO:0071625]	postsynapse organization [GO:0099173]; regulation of signal transduction [GO:0009966]	cell [GO:0005623]; cell junction [GO:0030054]; ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; neuron projection [GO:0043005]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	actin binding [GO:0003779]; GKAP/Homer scaffold activity [GO:0030160]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; protein C-terminus binding [GO:0008022]; protein self-association [GO:0043621]; receptor signaling complex adaptor activity [GO:0030159]; scaffold protein binding [GO:0097110]; SH3 domain binding [GO:0017124]; structural constituent of postsynaptic density [GO:0098919]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]
d2f4aa__d1c6ka___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2f4ea__d3prab___1	Viridiplantae		Streptophyta	Euryarchaeota	endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; calmodulin binding [GO:0005516]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; auxin-activated signaling pathway [GO:0009734]; leaf development [GO:0048366]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	auxin-activated signaling pathway [GO:0009734]; leaf development [GO:0048366]		endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]		calmodulin binding [GO:0005516]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2f4ga__d1ky1a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2f4oa2_d1x9ya1__1	Metazoa		Chordata	Firmicutes	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]; glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]; pathogenesis [GO:0009405]	glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	pathogenesis [GO:0009405]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]	cysteine-type peptidase activity [GO:0008234]
d2f4vp1_d2gy9p1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d2f4vq1_d1qzhe___1		Fungi	Deinococcus-Thermus	Ascomycota	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytosol [GO:0005829]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]; nuclear telomeric heterochromatin [GO:0005724]; nucleus [GO:0005634]; shelterin complex [GO:0070187]; telomere cap complex [GO:0000782]; G-rich strand telomeric DNA binding [GO:0098505]; single-stranded telomeric DNA binding [GO:0043047]; telomerase inhibitor activity [GO:0010521]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]	translation [GO:0006412]	negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]	ribosome [GO:0005840]	cytosol [GO:0005829]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]; nuclear telomeric heterochromatin [GO:0005724]; nucleus [GO:0005634]; shelterin complex [GO:0070187]; telomere cap complex [GO:0000782]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	G-rich strand telomeric DNA binding [GO:0098505]; single-stranded telomeric DNA binding [GO:0043047]; telomerase inhibitor activity [GO:0010521]
d2f4yc__d2c4ba1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d2f51b1_d4j56g1__1				Apicomplexa	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]	protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d2f53d1_d5i1el1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]			
d2f54a1_d5ihzd2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]			
d2f54b2_d1cica2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2f54e2_d4aeim1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	defense response [GO:0006952]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]		sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]
d2f54f1_d1t03h1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2f54g2_d1ndmb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2f54g2_d2ak4j2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2f54l1_d4nqde1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2f54l2_d3qcul2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2f58h2_d1rz8a1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2f58l2_d3hb3d___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2f5al2_d4qnpf1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2f5bl1_d2lvca1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	3M complex [GO:1990393]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; M band [GO:0031430]; perinuclear region of cytoplasm [GO:0048471]; Z disc [GO:0030018]; cytoskeletal adaptor activity [GO:0008093]; cardiac myofibril assembly [GO:0055003]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of dendrite morphogenesis [GO:0050775]; post-translational protein modification [GO:0043687]; protein localization to Golgi apparatus [GO:0034067]; regulation of mitotic nuclear division [GO:0007088]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cardiac myofibril assembly [GO:0055003]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of dendrite morphogenesis [GO:0050775]; post-translational protein modification [GO:0043687]; protein localization to Golgi apparatus [GO:0034067]; regulation of mitotic nuclear division [GO:0007088]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	3M complex [GO:1990393]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; M band [GO:0031430]; perinuclear region of cytoplasm [GO:0048471]; Z disc [GO:0030018]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	cytoskeletal adaptor activity [GO:0008093]
d2f5ma__d1uclb___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d2f5ya1_d4joea___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; inactivation of MAPK activity [GO:0000188]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	G protein-coupled receptor signaling pathway [GO:0007186]; inactivation of MAPK activity [GO:0000188]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	ion channel binding [GO:0044325]
d2f5yb2_d4oepb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; inactivation of MAPK activity [GO:0000188]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell projection [GO:0042995]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	G protein-coupled receptor signaling pathway [GO:0007186]; inactivation of MAPK activity [GO:0000188]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of cell migration [GO:0030335]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]
d2f61a2_d4cgta4__1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	extracellular region [GO:0005576]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2f61b2_d1gora___1	Metazoa	Fungi	Chordata	Ascomycota	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	xylan catabolic process [GO:0045493]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	endo-1,4-beta-xylanase activity [GO:0031176]
d2f6ca2_d1h86b2__1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	periplasmic space [GO:0042597]; flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]		polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	periplasmic space [GO:0042597]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]
d2f6fa1_d4hrfd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; p53 binding [GO:0002039]; phosphoprotein phosphatase activity [GO:0004721]; phosphoserine phosphatase activity [GO:0004647]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; RNA polymerase II activating transcription factor binding [GO:0001102]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell adhesion [GO:0045785]; positive regulation of peptidyl-serine dephosphorylation [GO:1902310]; protein dephosphorylation [GO:0006470]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell adhesion [GO:0045785]; positive regulation of peptidyl-serine dephosphorylation [GO:1902310]; protein dephosphorylation [GO:0006470]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	p53 binding [GO:0002039]; phosphoprotein phosphatase activity [GO:0004721]; phosphoserine phosphatase activity [GO:0004647]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]; RNA polymerase II activating transcription factor binding [GO:0001102]
d2f6la1_d4oj7f___1			Actinobacteria		extracellular region [GO:0005576]; chorismate mutase activity [GO:0004106]; chorismate metabolic process [GO:0046417]		chorismate metabolic process [GO:0046417]		extracellular region [GO:0005576]		chorismate mutase activity [GO:0004106]	
d2f6ua1_d2bsla___1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; phosphoglycerol geranylgeranyltransferase activity [GO:0047294]; polyprenyltransferase activity [GO:0002094]; glycerophospholipid biosynthetic process [GO:0046474]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	glycerophospholipid biosynthetic process [GO:0046474]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; phosphoglycerol geranylgeranyltransferase activity [GO:0047294]; polyprenyltransferase activity [GO:0002094]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d2f6va__d3qkqa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2f73d2_d1ywba___1	Metazoa	Metazoa	Chordata	Arthropoda	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	vasodilation [GO:0042311]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d2f73g2_d2fs7b___1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d2f74b2_d3fo2a1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2f74e__d5kanl1__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]
d2f7da1_d3ovxb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; negative regulation of cartilage development [GO:0061037]; proteolysis involved in cellular protein catabolic process [GO:0051603]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; negative regulation of cartilage development [GO:0061037]; proteolysis involved in cellular protein catabolic process [GO:0051603]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	extracellular space [GO:0005615]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d2f7fa1_d2b7pa2__1			Firmicutes	Proteobacteria	nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]		cytoplasm [GO:0005737]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2f7fa2_d2i14b2__1			Firmicutes	Euryarchaeota	nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]			nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2f7mf__d3kb9a___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	epi-isozizaene synthase activity [GO:0052680]; metal ion binding [GO:0046872]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]		dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	epi-isozizaene synthase activity [GO:0052680]; metal ion binding [GO:0046872]
d2f7oa2_d3t09a5__1	Metazoa		Arthropoda	Proteobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	beta-galactosidase complex [GO:0009341]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2f7pa2_d3vd9c5__1	Metazoa		Arthropoda	Proteobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	beta-galactosidase complex [GO:0009341]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2f7ra1_d1k1yb1__1	Metazoa		Arthropoda	Euryarchaeota	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]
d2f80b__d5p7ca___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2f81b__d5p7ha___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2f86d__d4l7kk___1	Metazoa		Nematoda (roundworms)	Proteobacteria	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	steroid metabolic process [GO:0008202]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]		ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	steroid delta-isomerase activity [GO:0004769]
d2f86d__d4nhff___1	Metazoa		Nematoda (roundworms)	Proteobacteria	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; protein secretion by the type IV secretion system [GO:0030255]	MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	protein secretion by the type IV secretion system [GO:0030255]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2f86f__d1aska___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]
d2f86h__d1nwwa___1	Metazoa		Nematoda (roundworms)	Actinobacteria	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	limonene-1,2-epoxide hydrolase activity [GO:0018744]	MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]		axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]		ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d2f86h__d2gbxb___1	Metazoa		Nematoda (roundworms)	Proteobacteria	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]	MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	cellular aromatic compound metabolic process [GO:0006725]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]		ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]
d2f86j__d2gbwd___1	Metazoa		Nematoda (roundworms)	Proteobacteria	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]	MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	cellular aromatic compound metabolic process [GO:0006725]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]		ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]
d2f86l__d3i1vb2__1	Metazoa		Nematoda (roundworms)		axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]		MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]		axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]		ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	
d2f8aa1_d3zl5b___1	Metazoa	Metazoa	Chordata	Platyhelminthes	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; SH3 domain binding [GO:0017124]; angiogenesis involved in wound healing [GO:0060055]; blood vessel endothelial cell migration [GO:0043534]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; endothelial cell development [GO:0001885]; fat cell differentiation [GO:0045444]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide catabolic process [GO:0042744]; interaction with symbiont [GO:0051702]; lipoxygenase pathway [GO:0019372]; myoblast proliferation [GO:0051450]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of supramolecular fiber organization [GO:1902905]; protein oxidation [GO:0018158]; purine nucleotide catabolic process [GO:0006195]; regulation of gene expression, epigenetic [GO:0040029]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of proteasomal protein catabolic process [GO:0061136]; response to gamma radiation [GO:0010332]; response to hydrogen peroxide [GO:0042542]; response to hydroperoxide [GO:0033194]; response to selenium ion [GO:0010269]; response to symbiotic bacterium [GO:0009609]; response to xenobiotic stimulus [GO:0009410]; sensory perception of sound [GO:0007605]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue regeneration [GO:0043403]; temperature homeostasis [GO:0001659]; triglyceride metabolic process [GO:0006641]; UV protection [GO:0009650]; vasodilation [GO:0042311]	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	angiogenesis involved in wound healing [GO:0060055]; blood vessel endothelial cell migration [GO:0043534]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; endothelial cell development [GO:0001885]; fat cell differentiation [GO:0045444]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide catabolic process [GO:0042744]; interaction with symbiont [GO:0051702]; lipoxygenase pathway [GO:0019372]; myoblast proliferation [GO:0051450]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of supramolecular fiber organization [GO:1902905]; protein oxidation [GO:0018158]; purine nucleotide catabolic process [GO:0006195]; regulation of gene expression, epigenetic [GO:0040029]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of proteasomal protein catabolic process [GO:0061136]; response to gamma radiation [GO:0010332]; response to hydrogen peroxide [GO:0042542]; response to hydroperoxide [GO:0033194]; response to selenium ion [GO:0010269]; response to symbiotic bacterium [GO:0009609]; response to xenobiotic stimulus [GO:0009410]; sensory perception of sound [GO:0007605]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue regeneration [GO:0043403]; temperature homeostasis [GO:0001659]; triglyceride metabolic process [GO:0006641]; UV protection [GO:0009650]; vasodilation [GO:0042311]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; SH3 domain binding [GO:0017124]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2f8fa2_d3m9kb___1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]		activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	glutathione transferase activity [GO:0004364]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d2f8fb1_d2hqtj2__1	Metazoa	Fungi	Platyhelminthes	Ascomycota	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]; enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]; positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]		positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]	glutathione transferase activity [GO:0004364]	enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]
d2f8fb2_d1uulj___1	Metazoa		Platyhelminthes		glutathione transferase activity [GO:0004364]						glutathione transferase activity [GO:0004364]	
d2f8jc__d3pd6a___1		Metazoa	Thermotogae	Chordata	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	cell surface [GO:0009986]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; T-tubule [GO:0030315]; amino acid binding [GO:0016597]; carboxylic acid binding [GO:0031406]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; dicarboxylic acid metabolic process [GO:0043648]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]	histidine biosynthetic process [GO:0000105]	2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; dicarboxylic acid metabolic process [GO:0043648]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]		cell surface [GO:0009986]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; T-tubule [GO:0030315]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]	amino acid binding [GO:0016597]; carboxylic acid binding [GO:0031406]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]
d2f8jd__d2cstb___1		Metazoa	Thermotogae	Chordata	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	cytosol [GO:0005829]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]	histidine biosynthetic process [GO:0000105]	2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]		cytosol [GO:0005829]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]	L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; pyridoxal phosphate binding [GO:0030170]
d2f8nd__d3aywa___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2f8ne__d5b1mf___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; nucleosome assembly [GO:0006334]		nucleosome assembly [GO:0006334]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2f8nf__d1m1aa___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; DNA-templated transcription, initiation [GO:0006352]		DNA-templated transcription, initiation [GO:0006352]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2f8oa__d1r24b1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2f8oa__d1w0wb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2f8ob__d2hwzl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2f8qb__d1j18a2__1			Firmicutes	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2f8sa3_d3vnaa___1		Viridiplantae	Aquificae	Streptophyta	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; adaxial/abaxial pattern specification [GO:0009955]; adventitious root development [GO:0048830]; auxin metabolic process [GO:0009850]; cell differentiation [GO:0030154]; defense response to virus [GO:0051607]; gene silencing by miRNA [GO:0035195]; innate immune response [GO:0045087]; leaf morphogenesis [GO:0009965]; leaf proximal/distal pattern formation [GO:0010589]; leaf vascular tissue pattern formation [GO:0010305]; posttranscriptional gene silencing [GO:0016441]; regulation of translation [GO:0006417]; response to auxin [GO:0009733]; response to far red light [GO:0010218]; viral gene silencing in virus induced gene silencing [GO:0060145]; viral process [GO:0016032]; virus induced gene silencing [GO:0009616]		adaxial/abaxial pattern specification [GO:0009955]; adventitious root development [GO:0048830]; auxin metabolic process [GO:0009850]; cell differentiation [GO:0030154]; defense response to virus [GO:0051607]; gene silencing by miRNA [GO:0035195]; innate immune response [GO:0045087]; leaf morphogenesis [GO:0009965]; leaf proximal/distal pattern formation [GO:0010589]; leaf vascular tissue pattern formation [GO:0010305]; posttranscriptional gene silencing [GO:0016441]; regulation of translation [GO:0006417]; response to auxin [GO:0009733]; response to far red light [GO:0010218]; viral gene silencing in virus induced gene silencing [GO:0060145]; viral process [GO:0016032]; virus induced gene silencing [GO:0009616]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]
d2f8tb3_d3vnba___1		Viridiplantae	Aquificae	Streptophyta	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; adaxial/abaxial pattern specification [GO:0009955]; adventitious root development [GO:0048830]; auxin metabolic process [GO:0009850]; cell differentiation [GO:0030154]; defense response to virus [GO:0051607]; gene silencing by miRNA [GO:0035195]; innate immune response [GO:0045087]; leaf morphogenesis [GO:0009965]; leaf proximal/distal pattern formation [GO:0010589]; leaf vascular tissue pattern formation [GO:0010305]; posttranscriptional gene silencing [GO:0016441]; regulation of translation [GO:0006417]; response to auxin [GO:0009733]; response to far red light [GO:0010218]; viral gene silencing in virus induced gene silencing [GO:0060145]; viral process [GO:0016032]; virus induced gene silencing [GO:0009616]		adaxial/abaxial pattern specification [GO:0009955]; adventitious root development [GO:0048830]; auxin metabolic process [GO:0009850]; cell differentiation [GO:0030154]; defense response to virus [GO:0051607]; gene silencing by miRNA [GO:0035195]; innate immune response [GO:0045087]; leaf morphogenesis [GO:0009965]; leaf proximal/distal pattern formation [GO:0010589]; leaf vascular tissue pattern formation [GO:0010305]; posttranscriptional gene silencing [GO:0016441]; regulation of translation [GO:0006417]; response to auxin [GO:0009733]; response to far red light [GO:0010218]; viral gene silencing in virus induced gene silencing [GO:0060145]; viral process [GO:0016032]; virus induced gene silencing [GO:0009616]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]
d2f8va2_d3ox8e1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2f8vb1_d1kenh1__1	Metazoa		Chordata	Negarnaviricota	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	host cell surface receptor binding [GO:0046789]
d2f8vb2_d2edqa1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]
d2f8vc2_d1tzgi2__1	Metazoa		Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	
d2f8vd1_d3c5zb1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d2f8ya__d3twrb___1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transmembrane signaling receptor activity [GO:0004888]; animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral genome replication [GO:0045070]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; regulation of transcription, DNA-templated [GO:0006355]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; in utero embryonic development [GO:0001701]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transmembrane signaling receptor activity [GO:0004888]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]
d2f8ya__d4a63b1__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transmembrane signaling receptor activity [GO:0004888]; animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral genome replication [GO:0045070]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; regulation of transcription, DNA-templated [GO:0006355]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; in utero embryonic development [GO:0001701]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transmembrane signaling receptor activity [GO:0004888]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2f8yb__d1g3nb___1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transmembrane signaling receptor activity [GO:0004888]; animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral genome replication [GO:0045070]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; regulation of transcription, DNA-templated [GO:0006355]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]; astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; in utero embryonic development [GO:0001701]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transmembrane signaling receptor activity [GO:0004888]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]
d2f8yb__d3twsa___1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transmembrane signaling receptor activity [GO:0004888]; animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral genome replication [GO:0045070]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; regulation of transcription, DNA-templated [GO:0006355]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; in utero embryonic development [GO:0001701]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transmembrane signaling receptor activity [GO:0004888]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]
d2f8zf__d4dxjc___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]		dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]
d2f90a__d2pa0b___1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	catalytic activity [GO:0003824]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]	catalytic activity [GO:0003824]
d2f90b__d3gw8a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]
d2f98b2_d5tuwf2__1			Actinobacteria	Cyanobacteria	intramolecular lyase activity [GO:0016872]; antibiotic biosynthetic process [GO:0017000]; daunorubicin biosynthetic process [GO:1901771]; doxorubicin metabolic process [GO:0044598]	phycobilisome [GO:0030089]; chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]; light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	antibiotic biosynthetic process [GO:0017000]; daunorubicin biosynthetic process [GO:1901771]; doxorubicin metabolic process [GO:0044598]	light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	intramolecular lyase activity [GO:0016872]	chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]
d2f98c2_d3gzxb___1			Actinobacteria	Proteobacteria	intramolecular lyase activity [GO:0016872]; antibiotic biosynthetic process [GO:0017000]; daunorubicin biosynthetic process [GO:1901771]; doxorubicin metabolic process [GO:0044598]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	antibiotic biosynthetic process [GO:0017000]; daunorubicin biosynthetic process [GO:1901771]; doxorubicin metabolic process [GO:0044598]	aromatic compound catabolic process [GO:0019439]			intramolecular lyase activity [GO:0016872]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2f9bh__d2gtba___1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2f9bt1_d4lpyb1__1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]		animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]		collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]		calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	
d2f9jb__d2mksa1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U12-type spliceosomal complex [GO:0005689]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; blastocyst formation [GO:0001825]; mRNA splicing, via spliceosome [GO:0000398]	catalytic step 2 spliceosome [GO:0071013]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; supraspliceosomal complex [GO:0044530]; chromatin binding [GO:0003682]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded RNA binding [GO:0003727]; cellular response to interleukin-1 [GO:0071347]; membrane protein ectodomain proteolysis [GO:0006509]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; osteoblast differentiation [GO:0001649]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; transcription by RNA polymerase II [GO:0006366]	blastocyst formation [GO:0001825]; mRNA splicing, via spliceosome [GO:0000398]	cellular response to interleukin-1 [GO:0071347]; membrane protein ectodomain proteolysis [GO:0006509]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; osteoblast differentiation [GO:0001649]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; transcription by RNA polymerase II [GO:0006366]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U12-type spliceosomal complex [GO:0005689]	catalytic step 2 spliceosome [GO:0071013]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; supraspliceosomal complex [GO:0044530]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	chromatin binding [GO:0003682]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded RNA binding [GO:0003727]
d2f9kf__d3wclb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d2f9nc__d1dvah___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d2f9ob__d2h5da___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase activity [GO:0004252]
d2f9oc__d1trma___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]
d2f9od__d3zz4b1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2fa4a__d1aqwc2__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; glutathione metabolic process [GO:0006749]; glycerol ether metabolic process [GO:0006662]; protein deglutathionylation [GO:0080058]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; sulfate assimilation [GO:0000103]; vacuole fusion, non-autophagic [GO:0042144]; vacuole inheritance [GO:0000011]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; glutathione metabolic process [GO:0006749]; glycerol ether metabolic process [GO:0006662]; protein deglutathionylation [GO:0080058]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; sulfate assimilation [GO:0000103]; vacuole fusion, non-autophagic [GO:0042144]; vacuole inheritance [GO:0000011]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2faca__d4zjbg1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d2fada__d3gzma___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	
d2faeb__d4bpha1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; D-alanyl carrier activity [GO:0036370]; cell wall organization [GO:0071555]; lipoteichoic acid biosynthetic process [GO:0070395]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	cell wall organization [GO:0071555]; lipoteichoic acid biosynthetic process [GO:0070395]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	D-alanyl carrier activity [GO:0036370]
d2fafb1_d1j3bb2__1	Metazoa		Chordata	Deinococcus-Thermus	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	gluconeogenesis [GO:0006094]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]
d2faha1_d3dtba1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]
d2fahc1_d2qeya1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]
d2fahc2_d1ii2a1__1	Metazoa		Chordata		cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	glycosome [GO:0020015]; ATP binding [GO:0005524]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	gluconeogenesis [GO:0006094]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glycosome [GO:0020015]	GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]	ATP binding [GO:0005524]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]
d2fahd1_d2olra2__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	cytosol [GO:0005829]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	gluconeogenesis [GO:0006094]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]
d2fak1__d4r00h___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fak2__d3hyeg___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2faka__d4qvpk___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fakb__d5l60j___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fakd__d4r00q___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fake__d4qv8w___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fakk__d5l5wu___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fakm__d5l5uf___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fako__d4qv9q___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fakp__d5l64q___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2faks__d4qvnn___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2faks__d5gs7a___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	choloylglycine hydrolase activity [GO:0045302]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	choloylglycine hydrolase activity [GO:0045302]
d2fakt__d4qwsq___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fakv__d1ofim___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein unfolding [GO:0043335]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	HslUV protease complex [GO:0009376]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]
d2fakx__d2gaw.2__1	Fungi		Ascomycota	Bacteroidetes	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	periplasmic space [GO:0042597]; N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity [GO:0003948]; peptidase activity [GO:0008233]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	periplasmic space [GO:0042597]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity [GO:0003948]; peptidase activity [GO:0008233]
d2fapa__d4diph___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	endoplasmic reticulum lumen [GO:0005788]; calcium ion binding [GO:0005509]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; IRE1-mediated unfolded protein response [GO:0036498]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	IRE1-mediated unfolded protein response [GO:0036498]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	endoplasmic reticulum lumen [GO:0005788]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	calcium ion binding [GO:0005509]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2fath1_d5jdjm___1		Metazoa		Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d2fatl1_d4lvea___1		Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d2fb2a__d2fb3a___1			Firmicutes	Firmicutes	molybdopterin synthase complex [GO:0019008]; 4 iron, 4 sulfur cluster binding [GO:0051539]; GTP 3',8'-cyclase activity [GO:0061798]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; S-adenosyl-L-methionine binding [GO:1904047]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdopterin synthase complex [GO:0019008]; 4 iron, 4 sulfur cluster binding [GO:0051539]; GTP 3',8'-cyclase activity [GO:0061798]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; S-adenosyl-L-methionine binding [GO:1904047]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdopterin synthase complex [GO:0019008]	molybdopterin synthase complex [GO:0019008]	4 iron, 4 sulfur cluster binding [GO:0051539]; GTP 3',8'-cyclase activity [GO:0061798]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; S-adenosyl-L-methionine binding [GO:1904047]	4 iron, 4 sulfur cluster binding [GO:0051539]; GTP 3',8'-cyclase activity [GO:0061798]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; S-adenosyl-L-methionine binding [GO:1904047]
d2fb2b__d1r30b___1			Firmicutes	Proteobacteria	molybdopterin synthase complex [GO:0019008]; 4 iron, 4 sulfur cluster binding [GO:0051539]; GTP 3',8'-cyclase activity [GO:0061798]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; S-adenosyl-L-methionine binding [GO:1904047]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; biotin synthase activity [GO:0004076]; iron ion binding [GO:0005506]; biotin biosynthetic process [GO:0009102]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	biotin biosynthetic process [GO:0009102]	molybdopterin synthase complex [GO:0019008]		4 iron, 4 sulfur cluster binding [GO:0051539]; GTP 3',8'-cyclase activity [GO:0061798]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; S-adenosyl-L-methionine binding [GO:1904047]	2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; biotin synthase activity [GO:0004076]; iron ion binding [GO:0005506]
d2fb2b__d2fb3b___1			Firmicutes	Firmicutes	molybdopterin synthase complex [GO:0019008]; 4 iron, 4 sulfur cluster binding [GO:0051539]; GTP 3',8'-cyclase activity [GO:0061798]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; S-adenosyl-L-methionine binding [GO:1904047]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdopterin synthase complex [GO:0019008]; 4 iron, 4 sulfur cluster binding [GO:0051539]; GTP 3',8'-cyclase activity [GO:0061798]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; S-adenosyl-L-methionine binding [GO:1904047]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdopterin synthase complex [GO:0019008]	molybdopterin synthase complex [GO:0019008]	4 iron, 4 sulfur cluster binding [GO:0051539]; GTP 3',8'-cyclase activity [GO:0061798]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; S-adenosyl-L-methionine binding [GO:1904047]	4 iron, 4 sulfur cluster binding [GO:0051539]; GTP 3',8'-cyclase activity [GO:0061798]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; S-adenosyl-L-methionine binding [GO:1904047]
d2fb4h2_d5t4zb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2fb4l2_d1u8ob1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2fb9a1_d1cs0e3__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2fbha1_d1j0rb___1			Proteobacteria	Firmicutes	DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; DNA replication termination [GO:0006274]	regulation of transcription, DNA-templated [GO:0006355]	DNA replication termination [GO:0006274]			DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]	DNA binding [GO:0003677]
d2fbjl1_d4x6bb2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2fbmb__d1szol___1	Metazoa		Chordata	Actinobacteria	nucleus [GO:0005634]; histone acetyltransferase activity [GO:0004402]; methylated histone binding [GO:0035064]; transcription corepressor activity [GO:0003714]; spermatogenesis [GO:0007283]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	spermatogenesis [GO:0007283]		nucleus [GO:0005634]		histone acetyltransferase activity [GO:0004402]; methylated histone binding [GO:0035064]; transcription corepressor activity [GO:0003714]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]
d2fbmc__d3ktkg___1	Metazoa		Chordata	Firmicutes	nucleus [GO:0005634]; histone acetyltransferase activity [GO:0004402]; methylated histone binding [GO:0035064]; transcription corepressor activity [GO:0003714]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	spermatogenesis [GO:0007283]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	histone acetyltransferase activity [GO:0004402]; methylated histone binding [GO:0035064]; transcription corepressor activity [GO:0003714]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]
d2fbra__d3nesa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d2fbwb1_d1jrog2__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]		mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]		2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d2fbwb1_d1r7sa___1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]		mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]		2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2fbwo1_d1rfkb___1	Metazoa		Chordata	Cyanobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]		mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]		2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2fbwo2_d1gthd1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d2fc3a1_d1vq8f1__1			Crenarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; ribosome biogenesis [GO:0042254]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome biogenesis [GO:0042254]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	translation [GO:0006412]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]	ribosome [GO:0005840]	ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2fcaa1_d5k09a1__1		Metazoa	Firmicutes	Chordata	tRNA (guanine-N7-)-methyltransferase activity [GO:0008176]; RNA (guanine-N7)-methylation [GO:0036265]; tRNA methylation [GO:0030488]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	RNA (guanine-N7)-methylation [GO:0036265]; tRNA methylation [GO:0030488]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	tRNA (guanine-N7-)-methyltransferase activity [GO:0008176]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d2fcba1_d2iepa1__1	Metazoa	Metazoa	Chordata	Chordata	cell body [GO:0044297]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; IgG binding [GO:0019864]; low-affinity IgG receptor activity [GO:0019772]; protein-containing complex binding [GO:0044877]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to amyloid-beta [GO:1904646]; cellular response to molecule of bacterial origin [GO:0071219]; cerebellum development [GO:0021549]; defense response [GO:0006952]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; follicular B cell differentiation [GO:0002316]; follicular dendritic cell activation [GO:0002266]; immune complex clearance by monocytes and macrophages [GO:0002436]; immune response [GO:0006955]; immunoglobulin mediated immune response [GO:0016064]; inflammatory response [GO:0006954]; mature B cell differentiation involved in immune response [GO:0002313]; negative regulation of acute inflammatory response to antigenic stimulus [GO:0002865]; negative regulation of antibody-dependent cellular cytotoxicity [GO:0001814]; negative regulation of B cell activation [GO:0050869]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of immune response [GO:0050777]; negative regulation of immunoglobulin production [GO:0002638]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of macrophage activation [GO:0043031]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of phagocytosis [GO:0050765]; negative regulation of type I hypersensitivity [GO:0001811]; phagocytosis, engulfment [GO:0006911]; positive regulation of humoral immune response [GO:0002922]; positive regulation of JNK cascade [GO:0046330]; positive regulation of neuron death [GO:1901216]; positive regulation of phagocytosis [GO:0050766]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; receptor-mediated endocytosis [GO:0006898]; regulation of adaptive immune response [GO:0002819]; regulation of B cell antigen processing and presentation [GO:0002622]; regulation of dendritic spine maintenance [GO:1902950]; regulation of immune complex clearance by monocytes and macrophages [GO:0090264]; regulation of immune response [GO:0050776]; regulation of innate immune response [GO:0045088]; regulation of signaling receptor activity [GO:0010469]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; viral process [GO:0016032]	cell junction [GO:0030054]; cell projection [GO:0042995]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; cochlea development [GO:0090102]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to muscle activity [GO:0014850]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to amyloid-beta [GO:1904646]; cellular response to molecule of bacterial origin [GO:0071219]; cerebellum development [GO:0021549]; defense response [GO:0006952]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; follicular B cell differentiation [GO:0002316]; follicular dendritic cell activation [GO:0002266]; immune complex clearance by monocytes and macrophages [GO:0002436]; immune response [GO:0006955]; immunoglobulin mediated immune response [GO:0016064]; inflammatory response [GO:0006954]; mature B cell differentiation involved in immune response [GO:0002313]; negative regulation of acute inflammatory response to antigenic stimulus [GO:0002865]; negative regulation of antibody-dependent cellular cytotoxicity [GO:0001814]; negative regulation of B cell activation [GO:0050869]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of immune response [GO:0050777]; negative regulation of immunoglobulin production [GO:0002638]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of macrophage activation [GO:0043031]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of phagocytosis [GO:0050765]; negative regulation of type I hypersensitivity [GO:0001811]; phagocytosis, engulfment [GO:0006911]; positive regulation of humoral immune response [GO:0002922]; positive regulation of JNK cascade [GO:0046330]; positive regulation of neuron death [GO:1901216]; positive regulation of phagocytosis [GO:0050766]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; receptor-mediated endocytosis [GO:0006898]; regulation of adaptive immune response [GO:0002819]; regulation of B cell antigen processing and presentation [GO:0002622]; regulation of dendritic spine maintenance [GO:1902950]; regulation of immune complex clearance by monocytes and macrophages [GO:0090264]; regulation of immune response [GO:0050776]; regulation of innate immune response [GO:0045088]; regulation of signaling receptor activity [GO:0010469]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; viral process [GO:0016032]	cochlea development [GO:0090102]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to muscle activity [GO:0014850]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell body [GO:0044297]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; cell projection [GO:0042995]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]	amyloid-beta binding [GO:0001540]; IgG binding [GO:0019864]; low-affinity IgG receptor activity [GO:0019772]; protein-containing complex binding [GO:0044877]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2fccb__d1vasa___1					class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; deoxyribodipyrimidine endonucleosidase activity [GO:0033959]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; pyrimidine dimer DNA N-glycosylase activity [GO:0000704]; DNA repair [GO:0006281]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; deoxyribodipyrimidine endonucleosidase activity [GO:0033959]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; pyrimidine dimer DNA N-glycosylase activity [GO:0000704]; DNA repair [GO:0006281]	DNA repair [GO:0006281]	DNA repair [GO:0006281]			class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; deoxyribodipyrimidine endonucleosidase activity [GO:0033959]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; pyrimidine dimer DNA N-glycosylase activity [GO:0000704]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; deoxyribodipyrimidine endonucleosidase activity [GO:0033959]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; pyrimidine dimer DNA N-glycosylase activity [GO:0000704]
d2fche__d4q5rf1__1		Metazoa	Proteobacteria	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	glutathione transferase activity [GO:0004364]
d2fchf__d1xoba___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2fchf__d2wfcd1__1		Metazoa	Proteobacteria	Annelida	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2fcia1_d1a81e1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; COP9 signalosome [GO:0008180]; lamellipodium [GO:0030027]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; phosphatidylinositol phospholipase C activity [GO:0004435]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; in utero embryonic development [GO:0001701]; inositol trisphosphate biosynthetic process [GO:0032959]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipid catabolic process [GO:0009395]; positive regulation of epithelial cell migration [GO:0010634]; release of sequestered calcium ion into cytosol [GO:0051209]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; inositol trisphosphate biosynthetic process [GO:0032959]; in utero embryonic development [GO:0001701]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipid catabolic process [GO:0009395]; positive regulation of epithelial cell migration [GO:0010634]; release of sequestered calcium ion into cytosol [GO:0051209]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell [GO:0005623]; COP9 signalosome [GO:0008180]; lamellipodium [GO:0030027]; ruffle [GO:0001726]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	calcium ion binding [GO:0005509]; phosphatidylinositol phospholipase C activity [GO:0004435]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]
d2fcra__d4zvnb___1		Metazoa	Rhodophyta	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d2fcua__d5pkna___1		Metazoa	Proteobacteria	Chordata		blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]		cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]		blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]		chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d2fd3a__d5eckf1__1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2fd5a1_d5myma1__1			Proteobacteria	Actinobacteria	DNA binding [GO:0003677]; positive regulation of melanin biosynthetic process [GO:0048023]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	positive regulation of melanin biosynthetic process [GO:0048023]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2fd6h1_d2ombb2__1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]		blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		serine-type endopeptidase activity [GO:0004252]	
d2fd6l1_d1lp9f2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	serine-type endopeptidase activity [GO:0004252]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2fd6l2_d5nbwa1__1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]		blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		serine-type endopeptidase activity [GO:0004252]	
d2fdbm1_d2aqzb1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2fdbm1_d3wo2a___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d2fdbr1_d4pljc1__1	Metazoa		Chordata		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	host cell cytoplasm [GO:0030430]; host cell surface [GO:0044228]; viral capsid [GO:0019028]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	host cell cytoplasm [GO:0030430]; host cell surface [GO:0044228]; viral capsid [GO:0019028]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2fdia__d5phka___1		Metazoa	Proteobacteria	Chordata	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]		blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d2fdka__d3o1pa___1			Proteobacteria	Proteobacteria	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]			1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]
d2fdub__d1og2b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; (S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	(S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d2fduc__d3wrje___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2fdud__d1rf9a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2fdud__d4g7gd___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d2fdwa__d4ipsa___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]
d2fdwb1_d3ofuc___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]		arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2fdxa__d1xyya___1			Firmicutes	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2fdyc__d1geja___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]		arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2fe1a1_d1v96b___1			Crenarchaeota	Euryarchaeota	magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]	magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]					magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]	magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]
d2fe8b2_d1nqca___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d2fe8c2_d1mira___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; melanosome [GO:0042470]; mitochondrion [GO:0005739]; sarcolemma [GO:0042383]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; kininogen binding [GO:0030984]; peptide binding [GO:0042277]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; autophagy [GO:0006914]; cellular response to mechanical stimulus [GO:0071260]; negative regulation of cell death [GO:0060548]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of catalytic activity [GO:0050790]; response to amine [GO:0014075]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to interleukin-4 [GO:0070670]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to wounding [GO:0009611]; skeletal muscle tissue development [GO:0007519]; spermatogenesis [GO:0007283]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	autophagy [GO:0006914]; cellular response to mechanical stimulus [GO:0071260]; negative regulation of cell death [GO:0060548]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of catalytic activity [GO:0050790]; response to amine [GO:0014075]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to interleukin-4 [GO:0070670]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to wounding [GO:0009611]; skeletal muscle tissue development [GO:0007519]; spermatogenesis [GO:0007283]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; melanosome [GO:0042470]; mitochondrion [GO:0005739]; sarcolemma [GO:0042383]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; kininogen binding [GO:0030984]; peptide binding [GO:0042277]; protein-containing complex binding [GO:0044877]; protein self-association [GO:0043621]
d2fecl2_d3cfkj1__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2fedd1_d4jfhe1__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2fedf1_d3cfke2__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2fedf2_d1v7no1__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]
d2feel1_d2jk5b1__1			Proteobacteria	Actinobacteria	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	voltage-gated potassium channel complex [GO:0008076]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d2feeo1_d1t5wb1__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d2fega1_d4q5qa1__1		Metazoa		Arthropoda		cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]				cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]
d2fera__d3g1qa___1			Proteobacteria		cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	(+)-camphor catabolic process [GO:0019383]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d2feua__d3i3kb___1			Proteobacteria		cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	
d2fewa__d1hyns___1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity [GO:0022872]; protein-phosphocysteine-mannitol phosphotransferase system transporter activity [GO:0090565]; mannitol transport [GO:0015797]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; Z disc [GO:0030018]; anion transmembrane transporter activity [GO:0008509]; anion:anion antiporter activity [GO:0015301]; ankyrin binding [GO:0030506]; bicarbonate transmembrane transporter activity [GO:0015106]; chloride transmembrane transporter activity [GO:0015108]; hemoglobin binding [GO:0030492]; inorganic anion exchanger activity [GO:0005452]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; anion transport [GO:0006820]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular ion homeostasis [GO:0006873]; chloride transport [GO:0006821]; erythrocyte development [GO:0048821]; glycolytic process [GO:0006096]; negative regulation of urine volume [GO:0035811]; pH elevation [GO:0045852]; plasma membrane phospholipid scrambling [GO:0017121]; protein localization to plasma membrane [GO:0072659]; regulation of intracellular pH [GO:0051453]	mannitol transport [GO:0015797]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	anion transport [GO:0006820]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular ion homeostasis [GO:0006873]; chloride transport [GO:0006821]; erythrocyte development [GO:0048821]; glycolytic process [GO:0006096]; negative regulation of urine volume [GO:0035811]; pH elevation [GO:0045852]; plasma membrane phospholipid scrambling [GO:0017121]; protein localization to plasma membrane [GO:0072659]; regulation of intracellular pH [GO:0051453]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; Z disc [GO:0030018]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity [GO:0022872]; protein-phosphocysteine-mannitol phosphotransferase system transporter activity [GO:0090565]	anion:anion antiporter activity [GO:0015301]; anion transmembrane transporter activity [GO:0008509]; ankyrin binding [GO:0030506]; bicarbonate transmembrane transporter activity [GO:0015106]; chloride transmembrane transporter activity [GO:0015108]; hemoglobin binding [GO:0030492]; inorganic anion exchanger activity [GO:0005452]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]
d2ff3a__d3fg6h1__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]
d2ff3b2_d1dgkn4__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d2ff4a3_d1yjma1__1	Fungi	Metazoa	Ascomycota	Chordata	chromatin [GO:0000785]; nucleus [GO:0005634]; double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; histone binding [GO:0042393]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; G1 DNA damage checkpoint [GO:0044783]; intra-S DNA damage checkpoint [GO:0031573]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of DNA replication [GO:0008156]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]	mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; double-stranded DNA binding [GO:0003690]; nucleoside monophosphate kinase activity [GO:0050145]; polynucleotide 3'-phosphatase activity [GO:0046403]; dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide phosphorylation [GO:0046939]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]	DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; G1 DNA damage checkpoint [GO:0044783]; intra-S DNA damage checkpoint [GO:0031573]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of DNA replication [GO:0008156]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]	dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide phosphorylation [GO:0046939]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]	chromatin [GO:0000785]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; histone binding [GO:0042393]	ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; double-stranded DNA binding [GO:0003690]; nucleoside monophosphate kinase activity [GO:0050145]; polynucleotide 3'-phosphatase activity [GO:0046403]
d2ff7a2_d1oxva2__1			Proteobacteria	Crenarchaeota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type I protein secretion system complex [GO:0030256]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; peptidase activity [GO:0008233]; toxin transmembrane transporter activity [GO:0019534]; protein secretion by the type I secretion system [GO:0030253]; secretion by cell [GO:0032940]; toxin transport [GO:1901998]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; carbohydrate transport [GO:0008643]	protein secretion by the type I secretion system [GO:0030253]; secretion by cell [GO:0032940]; toxin transport [GO:1901998]	carbohydrate transport [GO:0008643]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type I protein secretion system complex [GO:0030256]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]	ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; peptidase activity [GO:0008233]; toxin transmembrane transporter activity [GO:0019534]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]
d2ffha3_d5l3sa2__1			Deinococcus-Thermus	Crenarchaeota	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]	signal recognition particle [GO:0048500]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d2ffhc3_d1q12c2__1			Deinococcus-Thermus	Proteobacteria	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]; activating transcription factor binding [GO:0033613]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	signal recognition particle [GO:0048500]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	activating transcription factor binding [GO:0033613]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; ATP binding [GO:0005524]
d2ffxj__d4toex___1	Metazoa		Chordata	Proteobacteria	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2fg6d2_d1js1z1__1			Bacteroidetes	Bacteroidetes	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	arginine biosynthetic process [GO:0006526]	arginine biosynthetic process [GO:0006526]			amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]
d2fg6d2_d4eknb1__1			Bacteroidetes	Euryarchaeota	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d2fg6x2_d2w37a1__1			Bacteroidetes	Firmicutes	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]	arginine biosynthetic process [GO:0006526]	arginine catabolic process to ornithine [GO:0019547]		cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]
d2fg6z1_d4fyyc2__1			Bacteroidetes	Proteobacteria	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2fg6z2_d3e2pb1__1			Bacteroidetes	Euryarchaeota	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d2fg7z2_d4jqob2__1			Bacteroidetes	Proteobacteria	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	arginine biosynthetic process [GO:0006526]	arginine biosynthetic process [GO:0006526]		cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d2fg8c__d2xkqc___1	Metazoa		Chordata	Firmicutes	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d2fg8d__d3oljd1__1	Metazoa	Metazoa	Chordata	Chordata	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2fg8g__d2xz0a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	fatty acid biosynthetic process [GO:0006633]	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]	chloroplast [GO:0009507]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d2fg8h__d4gamq___1	Metazoa		Chordata	Proteobacteria	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2fgha2_d1rgig1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2fgha4_d1wnja1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; site of polarized growth [GO:0030427]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]; defense response to fungus [GO:0050832]; neutrophil degranulation [GO:0043312]; regulation of actin filament polymerization [GO:0030833]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	defense response to fungus [GO:0050832]; neutrophil degranulation [GO:0043312]; regulation of actin filament polymerization [GO:0030833]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; site of polarized growth [GO:0030427]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]
d2fghb6_d1rgig3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2fglb__d1b3ya___1		Fungi	Firmicutes	Ascomycota	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d2fglb__d2zwzb1__1			Firmicutes	Thermotogae	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	xylan catabolic process [GO:0045493]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]		lysosome [GO:0005764]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]	alpha-L-fucosidase activity [GO:0004560]
d2fgua__d5pepa___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2fgvb__d3ndxa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2fgwl1_d3juyc1__1												
d2fgwl2_d3cdff___1		Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d2fgwl2_d3czfb1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2fgza3_d1tr1a___1			Proteobacteria	Firmicutes	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d2fgza3_d1wzla3__1			Proteobacteria	Firmicutes	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2fh1a2_d1esvs___1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2fh1a2_d3fg6e2__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]
d2fh1b2_d4cbxg___1	Metazoa		Chordata	Apicomplexa	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; ATP binding [GO:0005524]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]		actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	ATP binding [GO:0005524]
d2fh1c3_d1nm1g___1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d2fh2b2_d2xfab___1	Metazoa		Chordata	Apicomplexa	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cytoskeleton [GO:0015629]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament depolymerization [GO:0030042]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cytoskeleton [GO:0015629]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]
d2fh2c3_d1d0na3__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d2fh3a1_d1d0nb1__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d2fh3a2_d3ffkd3__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2fh3b2_d1j72a2__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]
d2fh3c3_d2kvka1__1	Metazoa		Chordata		actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cytoskeleton [GO:0015629]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament depolymerization [GO:0030042]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cytoskeleton [GO:0015629]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]
d2fh4a2_d2fh1b3__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d2fh4b2_d3q2ba___1	Metazoa		Chordata	Apicomplexa	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; actin monomer binding [GO:0003785]; actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin monomer binding [GO:0003785]
d2fh4c2_d1h1vg3__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2fh6a2_d1ukta1__1			Proteobacteria	Firmicutes	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2fh6a3_d2d1zb1__1			Proteobacteria	Actinobacteria	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	endo-1,4-beta-xylanase activity [GO:0031176]
d2fh6a3_d4flra1__1			Proteobacteria	Proteobacteria	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	amylosucrase activity [GO:0047669]
d2fh7a1_d4qapa___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2fh8a1_d3jv5a___1		Metazoa	Proteobacteria	Chordata	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	Bcl3/NF-kappaB2 complex [GO:0033257]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; aging [GO:0007568]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; rhythmic process [GO:0048511]; spleen development [GO:0048536]	carbohydrate metabolic process [GO:0005975]	aging [GO:0007568]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; rhythmic process [GO:0048511]; spleen development [GO:0048536]	plasma membrane [GO:0005886]	Bcl3/NF-kappaB2 complex [GO:0033257]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d2fh8a3_d3blka1__1		Metazoa	Proteobacteria	Chordata	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d2fhba1_d1pzul1__1		Metazoa	Proteobacteria	Chordata	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	carbohydrate metabolic process [GO:0005975]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d2fhba4_d1ea9d2__1			Proteobacteria	Firmicutes	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	cyclomaltodextrinase activity [GO:0047798]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	cyclomaltodextrinase activity [GO:0047798]
d2fhba4_d1xsjb3__1			Proteobacteria	Proteobacteria	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d2fhca1_d1wzkb1__1			Proteobacteria	Firmicutes	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2fhca2_d1cxka1__1			Proteobacteria	Firmicutes	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	plasma membrane [GO:0005886]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2fhca2_d2o93l1__1		Metazoa	Proteobacteria	Chordata	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	carbohydrate metabolic process [GO:0005975]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d2fhca4_d3h54b2__1		Metazoa	Proteobacteria	Chordata	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d2fhea2_d4hj2a1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione transferase activity [GO:0004364]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2fheb2_d1f3ba2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; steroid delta-isomerase activity [GO:0004769]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]		glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]	glutathione transferase activity [GO:0004364]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; steroid delta-isomerase activity [GO:0004769]
d2fhfa2_d4pyge1__1		Metazoa	Proteobacteria	Chordata	plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	carbohydrate metabolic process [GO:0005975]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	plasma membrane [GO:0005886]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d2fhhj__d5le5f___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fhhl__d3gpwn___1		Fungi	Actinobacteria	Ascomycota	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fhhr__d5dkib___1		Fungi	Actinobacteria	Ascomycota	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fhny__d3szia___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2fhsa__d3vpff1__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]		fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	
d2fhta1_d1zxta1__1					extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; chemokine activity [GO:0008009]; CXCR chemokine receptor binding [GO:0045236]; immune response [GO:0006955]	extracellular region [GO:0005576]; chemokine activity [GO:0008009]; immune response [GO:0006955]	immune response [GO:0006955]	immune response [GO:0006955]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	chemokine activity [GO:0008009]; CXCR chemokine receptor binding [GO:0045236]	chemokine activity [GO:0008009]
d2fi1a1_d2r8yl___1			Firmicutes	Proteobacteria	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]			hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d2fiaa1_d5dwmd___1			Firmicutes	Proteobacteria	N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]					N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]
d2fiab__d3k9ub___1			Firmicutes	Euryarchaeota	N-acetyltransferase activity [GO:0008080]	diamine N-acetyltransferase activity [GO:0004145]; negative regulation of sporulation [GO:0043939]		negative regulation of sporulation [GO:0043939]			N-acetyltransferase activity [GO:0008080]	diamine N-acetyltransferase activity [GO:0004145]
d2fifc__d1nddb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2fife__d5aekd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d2fika1_d1iqwl2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2fikb__d1jnlh1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2finb__d5d65b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR1 chemokine receptor binding [GO:0031726]; CCR5 chemokine receptor binding [GO:0031730]; chemokine activity [GO:0008009]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; establishment or maintenance of cell polarity [GO:0007163]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; neutrophil chemotaxis [GO:0030593]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of natural killer cell chemotaxis [GO:2000503]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; signal transduction [GO:0007165]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium-dependent protein kinase C activity [GO:0004698]; CCR chemokine receptor binding [GO:0048020]; CCR1 chemokine receptor binding [GO:0031726]; CCR5 chemokine receptor binding [GO:0031730]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; phospholipase activator activity [GO:0016004]; protein kinase activity [GO:0004672]; astrocyte cell migration [GO:0043615]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell activation [GO:0001775]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; eosinophil degranulation [GO:0043308]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; granulocyte chemotaxis [GO:0071621]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of bone mineralization [GO:0030502]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast differentiation [GO:0045671]; neutrophil chemotaxis [GO:0030593]; osteoblast differentiation [GO:0001649]; positive regulation of calcium ion import [GO:0090280]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; protein kinase B signaling [GO:0043491]; regulation of behavior [GO:0050795]; regulation of cell shape [GO:0008360]; regulation of sensory perception of pain [GO:0051930]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to cholesterol [GO:0070723]; response to toxic substance [GO:0009636]; signaling [GO:0023052]; T cell chemotaxis [GO:0010818]	cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; establishment or maintenance of cell polarity [GO:0007163]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; neutrophil chemotaxis [GO:0030593]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of natural killer cell chemotaxis [GO:2000503]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; signal transduction [GO:0007165]	astrocyte cell migration [GO:0043615]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell activation [GO:0001775]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; eosinophil degranulation [GO:0043308]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; granulocyte chemotaxis [GO:0071621]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of bone mineralization [GO:0030502]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast differentiation [GO:0045671]; neutrophil chemotaxis [GO:0030593]; osteoblast differentiation [GO:0001649]; positive regulation of calcium ion import [GO:0090280]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; protein kinase B signaling [GO:0043491]; regulation of behavior [GO:0050795]; regulation of cell shape [GO:0008360]; regulation of sensory perception of pain [GO:0051930]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to cholesterol [GO:0070723]; response to toxic substance [GO:0009636]; signaling [GO:0023052]; T cell chemotaxis [GO:0010818]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	CCR1 chemokine receptor binding [GO:0031726]; CCR5 chemokine receptor binding [GO:0031730]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]	calcium-dependent protein kinase C activity [GO:0004698]; CCR1 chemokine receptor binding [GO:0031726]; CCR5 chemokine receptor binding [GO:0031730]; CCR chemokine receptor binding [GO:0048020]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; phospholipase activator activity [GO:0016004]; protein kinase activity [GO:0004672]
d2fivb__d4y5pa___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]				aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2fj1a2_d5gp9b2__1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	DNA binding [GO:0003677]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]				DNA binding [GO:0003677]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d2fj2a1_d5cmde___1		Metazoa		Chordata	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; chemokine activity [GO:0008009]; CXCR chemokine receptor binding [GO:0045236]; immune response [GO:0006955]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR1 chemokine receptor binding [GO:0031726]; CCR4 chemokine receptor binding [GO:0031729]; CCR5 chemokine receptor binding [GO:0031730]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; chemokine receptor antagonist activity [GO:0046817]; chemokine receptor binding [GO:0042379]; identical protein binding [GO:0042802]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase activator activity [GO:0016004]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein self-association [GO:0043621]; receptor signaling protein tyrosine kinase activator activity [GO:0030298]; activation of phospholipase D activity [GO:0031584]; calcium ion transport [GO:0006816]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell chemotaxis [GO:0002407]; eosinophil chemotaxis [GO:0048245]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of viral genome replication [GO:0045071]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cellular biosynthetic process [GO:0031328]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of innate immune response [GO:0045089]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphorylation [GO:0042327]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell apoptotic process [GO:0070234]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of T cell migration [GO:2000406]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of translational initiation [GO:0045948]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of viral genome replication [GO:0045070]; protein kinase B signaling [GO:0043491]; regulation of chronic inflammatory response [GO:0002676]; regulation of insulin secretion [GO:0050796]; regulation of neuron death [GO:1901214]; regulation of T cell activation [GO:0050863]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]	immune response [GO:0006955]	activation of phospholipase D activity [GO:0031584]; calcium ion transport [GO:0006816]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell chemotaxis [GO:0002407]; eosinophil chemotaxis [GO:0048245]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of viral genome replication [GO:0045071]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular biosynthetic process [GO:0031328]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of innate immune response [GO:0045089]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphorylation [GO:0042327]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell apoptotic process [GO:0070234]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of T cell migration [GO:2000406]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of translational initiation [GO:0045948]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of viral genome replication [GO:0045070]; protein kinase B signaling [GO:0043491]; regulation of chronic inflammatory response [GO:0002676]; regulation of insulin secretion [GO:0050796]; regulation of neuron death [GO:1901214]; regulation of T cell activation [GO:0050863]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	chemokine activity [GO:0008009]; CXCR chemokine receptor binding [GO:0045236]	CCR1 chemokine receptor binding [GO:0031726]; CCR4 chemokine receptor binding [GO:0031729]; CCR5 chemokine receptor binding [GO:0031730]; CCR chemokine receptor binding [GO:0048020]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; chemokine receptor antagonist activity [GO:0046817]; chemokine receptor binding [GO:0042379]; identical protein binding [GO:0042802]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase activator activity [GO:0016004]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein self-association [GO:0043621]; receptor signaling protein tyrosine kinase activator activity [GO:0030298]
d2fj7a1_d1s32b___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2fj7d1_d4csrb___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	CCAAT-binding factor complex [GO:0016602]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; protein folding [GO:0006457]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]		protein folding [GO:0006457]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	CCAAT-binding factor complex [GO:0016602]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]
d2fj7h1_d3azib___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2fjcd__d4cybi___1			Spirochaetes	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2fjce__d4toao___1			Spirochaetes	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2fjcf__d3isef___1			Spirochaetes	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2fjcf__d3wnwb___1		Metazoa	Spirochaetes	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cellular iron ion homeostasis [GO:0006879]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2fjch__d3is7c___1			Spirochaetes	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2fjcj__d2xjoj___1			Spirochaetes	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d2fjcl__d5ls9d___1			Spirochaetes	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]
d2fjcm__d3ghqh___1			Spirochaetes	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2fjfa2_d5x2ml2__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; G protein-coupled receptor activity [GO:0004930]				integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		G protein-coupled receptor activity [GO:0004930]
d2fjfb1_d4z7va2__1		Viridiplantae		Streptophyta		nutrient reservoir activity [GO:0045735]						nutrient reservoir activity [GO:0045735]
d2fjfe1_d4hjga2__1				Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]		IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]
d2fjff1_d2gsig2__1				Firmicutes		extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]				extracellular region [GO:0005576]; membrane [GO:0016020]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2fjfh1_d5k9qy1__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d2fjfj1_d4wi9a2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2fjfl2_d5nixd1__1												
d2fjfm1_d1aifl2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2fjfn1_d2uudh1__1												
d2fjfo1_d5ugyn2__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d2fjfo2_d1moeb2__1		Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		
d2fjfp1_d4oz4l2__1												
d2fjfr1_d5nhwl2__1												
d2fjft1_d2ig2h2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2fjfw1_d1lo2h1__1		Metazoa		Chordata								
d2fjfx1_d2z35b___1		Metazoa		Chordata								
d2fjga1_d1igyd3__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2fjga1_d3qhzl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	
d2fjga2_d1wiua___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	A band [GO:0031672]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; structural constituent of muscle [GO:0008307]; adult locomotory behavior [GO:0008344]; behavioral response to nicotine [GO:0035095]; muscle contraction [GO:0006936]; negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of locomotion [GO:0040017]; positive regulation of sarcomere organization [GO:0060298]; positive regulation of striated muscle contraction [GO:0045989]; sarcomere organization [GO:0045214]; striated muscle myosin thick filament assembly [GO:0071688]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	adult locomotory behavior [GO:0008344]; behavioral response to nicotine [GO:0035095]; muscle contraction [GO:0006936]; negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of locomotion [GO:0040017]; positive regulation of sarcomere organization [GO:0060298]; positive regulation of striated muscle contraction [GO:0045989]; sarcomere organization [GO:0045214]; striated muscle myosin thick filament assembly [GO:0071688]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	A band [GO:0031672]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; structural constituent of muscle [GO:0008307]
d2fjgl1_d2r2ea2__1	Metazoa		Chordata		cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	
d2fjhl2_d1wwax___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome membrane [GO:0055038]; ATP binding [GO:0005524]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; nerve growth factor binding [GO:0048406]; nerve growth factor receptor activity [GO:0010465]; neurotrophin binding [GO:0043121]; neurotrophin p75 receptor binding [GO:0005166]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of MAPKK activity [GO:0000186]; aging [GO:0007568]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; B cell differentiation [GO:0030183]; behavioral response to formalin induced pain [GO:0061368]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to nicotine [GO:0071316]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; learning or memory [GO:0007611]; mechanoreceptor differentiation [GO:0042490]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; neurotrophin TRK receptor signaling pathway [GO:0048011]; olfactory nerve development [GO:0021553]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; programmed cell death involved in cell development [GO:0010623]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to hydrostatic pressure [GO:0051599]; response to nutrient levels [GO:0031667]; response to radiation [GO:0009314]; Sertoli cell development [GO:0060009]; sympathetic nervous system development [GO:0048485]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	activation of MAPKK activity [GO:0000186]; aging [GO:0007568]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; B cell differentiation [GO:0030183]; behavioral response to formalin induced pain [GO:0061368]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to nicotine [GO:0071316]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; learning or memory [GO:0007611]; mechanoreceptor differentiation [GO:0042490]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; neurotrophin TRK receptor signaling pathway [GO:0048011]; olfactory nerve development [GO:0021553]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; programmed cell death involved in cell development [GO:0010623]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to hydrostatic pressure [GO:0051599]; response to nutrient levels [GO:0031667]; response to radiation [GO:0009314]; Sertoli cell development [GO:0060009]; sympathetic nervous system development [GO:0048485]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome membrane [GO:0055038]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	ATP binding [GO:0005524]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; nerve growth factor binding [GO:0048406]; nerve growth factor receptor activity [GO:0010465]; neurotrophin binding [GO:0043121]; neurotrophin p75 receptor binding [GO:0005166]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2fjja__d2x1ba___1		Fungi		Ascomycota		mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; mRNA binding [GO:0003729]; mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]		mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]		mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]		mRNA binding [GO:0003729]
d2fjsc2_d3t71b1__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2fk0c2_d4kola___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2fk0c2_d4wsuc1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2fk0e2_d4wsxs___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2fk0g2_d5bqzc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2fk0o2_d5t6sk___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d2fk0q2_d5vtxa1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d2fk8a__d5k09j___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; plasma membrane [GO:0005886]; methyltransferase activity [GO:0008168]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; mycolic acid biosynthetic process [GO:0071768]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	mycolic acid biosynthetic process [GO:0071768]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	methyltransferase activity [GO:0008168]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d2fkpc2_d2oqyg2__1			Deinococcus-Thermus	Firmicutes	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	menaquinone biosynthetic process [GO:0009234]				hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]
d2fkpd2_d3pwib2__1			Deinococcus-Thermus	Proteobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	menaquinone biosynthetic process [GO:0009234]	D-glucarate catabolic process [GO:0042838]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d2fkuc__d5h8ij___1		Viridiplantae		Streptophyta		N-carbamoylputrescine amidase activity [GO:0050126]; polyamine biosynthetic process [GO:0006596]		polyamine biosynthetic process [GO:0006596]				N-carbamoylputrescine amidase activity [GO:0050126]
d2fkvb__d5h8il___1		Viridiplantae		Streptophyta		N-carbamoylputrescine amidase activity [GO:0050126]; polyamine biosynthetic process [GO:0006596]		polyamine biosynthetic process [GO:0006596]				N-carbamoylputrescine amidase activity [GO:0050126]
d2fkzb__d4n83c___1			Proteobacteria	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2fkze__d2cf7d___1			Proteobacteria	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d2fkzf__d1fz7d___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2fkzg__d5l89v___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]
d2fl0a__d2bk6e___1			Proteobacteria	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2fl0c__d5l89b___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]
d2fl0d__d1xvbb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2fl0e__d3rnfb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d2fl0g__d1l8hc___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2fl0h__d3a9qf___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2fl5e1_d4tsbl2__1	Metazoa	Metazoa	Chordata	Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2fl5e2_d5fm5p1__1	Metazoa	Metazoa	Chordata	Chordata		3M complex [GO:1990393]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; M band [GO:0031430]; perinuclear region of cytoplasm [GO:0048471]; Z disc [GO:0030018]; cytoskeletal adaptor activity [GO:0008093]; cardiac myofibril assembly [GO:0055003]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of dendrite morphogenesis [GO:0050775]; post-translational protein modification [GO:0043687]; protein localization to Golgi apparatus [GO:0034067]; regulation of mitotic nuclear division [GO:0007088]		cardiac myofibril assembly [GO:0055003]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of dendrite morphogenesis [GO:0050775]; post-translational protein modification [GO:0043687]; protein localization to Golgi apparatus [GO:0034067]; regulation of mitotic nuclear division [GO:0007088]		3M complex [GO:1990393]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; M band [GO:0031430]; perinuclear region of cytoplasm [GO:0048471]; Z disc [GO:0030018]		cytoskeletal adaptor activity [GO:0008093]
d2fl5l1_d2ajvl2__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2flea__d3cidb___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d2flhb__d2hmka2__1	Viridiplantae		Streptophyta	Proteobacteria	abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]	aromatic compound catabolic process [GO:0019439]			abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	dioxygenase activity [GO:0051213]
d2flhd__d5aeww2__1	Viridiplantae		Streptophyta	Proteobacteria	abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]	aromatic compound catabolic process [GO:0019439]			abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2flia1_d1tqxb___1			Firmicutes	Apicomplexa	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d2flie__d1q6la___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]			metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2flig__d2wjzc___1			Firmicutes	Thermotogae	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; histidine biosynthetic process [GO:0000105]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	histidine biosynthetic process [GO:0000105]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]	imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]
d2flii__d3li0b___1			Firmicutes	Euryarchaeota	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2flik__d3g1vb___1			Firmicutes	Euryarchaeota	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2flja__d5u6gd___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]		epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	lipid binding [GO:0008289]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d2flka__d5wq0f___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]		metal ion binding [GO:0046872]	
d2flrt1_d2aewb2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	cell surface [GO:0009986]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth hormone receptor complex [GO:0070195]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; growth hormone receptor activity [GO:0004903]; identical protein binding [GO:0042802]; peptide hormone binding [GO:0017046]; proline-rich region binding [GO:0070064]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; activation of Janus kinase activity [GO:0042976]; activation of MAPK activity [GO:0000187]; cellular response to hormone stimulus [GO:0032870]; endocytosis [GO:0006897]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; hormone metabolic process [GO:0042445]; insulin-like growth factor receptor signaling pathway [GO:0048009]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; receptor internalization [GO:0031623]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of multicellular organism growth [GO:0040014]; response to cycloheximide [GO:0046898]; response to estradiol [GO:0032355]; taurine metabolic process [GO:0019530]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	activation of Janus kinase activity [GO:0042976]; activation of MAPK activity [GO:0000187]; cellular response to hormone stimulus [GO:0032870]; endocytosis [GO:0006897]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; hormone metabolic process [GO:0042445]; insulin-like growth factor receptor signaling pathway [GO:0048009]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; receptor internalization [GO:0031623]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of multicellular organism growth [GO:0040014]; response to cycloheximide [GO:0046898]; response to estradiol [GO:0032355]; taurine metabolic process [GO:0019530]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	cell surface [GO:0009986]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth hormone receptor complex [GO:0070195]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; growth hormone receptor activity [GO:0004903]; identical protein binding [GO:0042802]; peptide hormone binding [GO:0017046]; proline-rich region binding [GO:0070064]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]
d2fm0c__d3gwta___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d2fm3a4_d3d5td2__1				Proteobacteria		L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]				L-malate dehydrogenase activity [GO:0030060]
d2fm4a__d5jvld2__1		Viridiplantae	Firmicutes	Streptophyta	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]	chloroplast [GO:0009507]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; photosynthesis [GO:0015979]; pyruvate metabolic process [GO:0006090]	pyruvate metabolic process [GO:0006090]	photosynthesis [GO:0015979]; pyruvate metabolic process [GO:0006090]		chloroplast [GO:0009507]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]
d2fm5c__d2ousb1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d2fmba__d1hxbb___1					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2fmfa__d3ltec___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]		metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d2fmha__d3nhzc___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; growth of symbiont in host [GO:0044117]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	growth of symbiont in host [GO:0044117]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]	metal ion binding [GO:0046872]	DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2fmia__d1zh2b___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of transcription, DNA-templated [GO:0006355]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	metal ion binding [GO:0046872]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2fmka__d4e7pa1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]		metal ion binding [GO:0046872]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d2fmpa3_d3v7ja3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d2fmta1_d4qpda2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; methionyl-tRNA formyltransferase activity [GO:0004479]; charged-tRNA amino acid modification [GO:0019988]; conversion of methionyl-tRNA to N-formyl-methionyl-tRNA [GO:0071951]	cytoplasm [GO:0005737]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydrolase activity [GO:0016787]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; embryonic viscerocranium morphogenesis [GO:0048703]; gastrulation [GO:0007369]; heart development [GO:0007507]; neural crest cell migration [GO:0001755]; neuromast deposition [GO:0048885]; one-carbon metabolic process [GO:0006730]	charged-tRNA amino acid modification [GO:0019988]; conversion of methionyl-tRNA to N-formyl-methionyl-tRNA [GO:0071951]	10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; embryonic viscerocranium morphogenesis [GO:0048703]; gastrulation [GO:0007369]; heart development [GO:0007507]; neural crest cell migration [GO:0001755]; neuromast deposition [GO:0048885]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	methionyl-tRNA formyltransferase activity [GO:0004479]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydrolase activity [GO:0016787]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]
d2fmya1_d4r8hb1__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d2fmyc1_d3ogjb___1		Metazoa	Firmicutes	Chordata	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	regulation of transcription, DNA-templated [GO:0006355]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]
d2fmyc2_d3wtvc___1		Metazoa	Firmicutes	Chordata	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; regulation of transcription, DNA-templated [GO:0006355]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	regulation of transcription, DNA-templated [GO:0006355]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]		core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]
d2fmyd1_d2wc2a1__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d2fn3a1_d1m2ja1__1			Proteobacteria	Euryarchaeota	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	mandelate catabolic process [GO:0019596]			cytoplasm [GO:0005737]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d2fn3a3_d1umca___1			Proteobacteria	Deinococcus-Thermus	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]
d2fn5a1_d4jokb___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell junction [GO:0030054]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; dendritic spine neck [GO:0044326]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; growth cone lamellipodium [GO:1990761]; lamellipodium [GO:0030027]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; postsynaptic actin cytoskeleton [GO:0098871]; postsynaptic density [GO:0014069]; synapse [GO:0045202]; actin filament binding [GO:0051015]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase 1 binding [GO:0008157]; protein-containing complex binding [GO:0044877]; actin filament organization [GO:0007015]; aging [GO:0007568]; calcium-mediated signaling [GO:0019722]; cellular response to toxic substance [GO:0097237]; excitatory postsynaptic potential [GO:0060079]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of spontaneous neurotransmitter secretion [GO:1904049]; negative regulation of stress fiber assembly [GO:0051497]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein kinase activity [GO:0045860]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of actin filament polymerization [GO:0030833]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of filopodium assembly [GO:0051489]; regulation of synapse assembly [GO:0051963]; regulation of synapse structural plasticity [GO:0051823]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	actin filament organization [GO:0007015]; aging [GO:0007568]; calcium-mediated signaling [GO:0019722]; cellular response to toxic substance [GO:0097237]; excitatory postsynaptic potential [GO:0060079]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of spontaneous neurotransmitter secretion [GO:1904049]; negative regulation of stress fiber assembly [GO:0051497]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein kinase activity [GO:0045860]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of actin filament polymerization [GO:0030833]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of filopodium assembly [GO:0051489]; regulation of synapse assembly [GO:0051963]; regulation of synapse structural plasticity [GO:0051823]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	actin cytoskeleton [GO:0015629]; cell junction [GO:0030054]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; dendritic spine neck [GO:0044326]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; growth cone lamellipodium [GO:1990761]; lamellipodium [GO:0030027]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; postsynaptic actin cytoskeleton [GO:0098871]; postsynaptic density [GO:0014069]; synapse [GO:0045202]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	actin filament binding [GO:0051015]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase 1 binding [GO:0008157]	ion channel binding [GO:0044325]
d2fn7b2_d3pqdg2__1			Apicomplexa	Firmicutes	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	L-lactate dehydrogenase activity [GO:0004459]
d2fn9b__d2puba2__1			Thermotogae	Proteobacteria		cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]; negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]		negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]		cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]
d2fnba__d1tfha2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]	cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]
d2fnca1_d4la9a___1			Thermotogae	Firmicutes	proteasome core complex, alpha-subunit complex [GO:0019773]; carbohydrate transmembrane transporter activity [GO:0015144]; endopeptidase activity [GO:0004175]; ubiquitin-dependent protein catabolic process [GO:0006511]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	ubiquitin-dependent protein catabolic process [GO:0006511]	nitrogen compound transport [GO:0071705]	proteasome core complex, alpha-subunit complex [GO:0019773]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	carbohydrate transmembrane transporter activity [GO:0015144]; endopeptidase activity [GO:0004175]	ligand-gated ion channel activity [GO:0015276]
d2fnea1_d4f8kb1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; protein C-terminus binding [GO:0008022]; cell adhesion [GO:0007155]; viral process [GO:0016032]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]; carnitine transport [GO:0015879]; in utero embryonic development [GO:0001701]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; protein localization to plasma membrane [GO:0072659]; regulation of anion transport [GO:0044070]	cell adhesion [GO:0007155]; viral process [GO:0016032]	carnitine transport [GO:0015879]; in utero embryonic development [GO:0001701]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; protein localization to plasma membrane [GO:0072659]; regulation of anion transport [GO:0044070]	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]	protein C-terminus binding [GO:0008022]	PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]
d2fneb2_d2dm8a1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; protein C-terminus binding [GO:0008022]; cell adhesion [GO:0007155]; viral process [GO:0016032]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	cell adhesion [GO:0007155]; viral process [GO:0016032]	bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	apical plasma membrane [GO:0016324]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; centriolar satellite [GO:0034451]; centrosome [GO:0005813]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	protein C-terminus binding [GO:0008022]	
d2fnec2_d1obzb2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; protein C-terminus binding [GO:0008022]; cell adhesion [GO:0007155]; viral process [GO:0016032]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]	cell adhesion [GO:0007155]; viral process [GO:0016032]	cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	protein C-terminus binding [GO:0008022]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]
d2fnia__d1wkhb___1			Proteobacteria	Deinococcus-Thermus	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; polysaccharide biosynthetic process [GO:0000271]	cytoplasm [GO:0005737]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	polysaccharide biosynthetic process [GO:0000271]	arginine metabolic process [GO:0006525]; lysine biosynthetic process via aminoadipic acid [GO:0019878]		cytoplasm [GO:0005737]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d2fnsa__d5p3ga___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2fnsb__d1psna___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular exosome [GO:0070062]; multivesicular body lumen [GO:0097486]; aspartic-type endopeptidase activity [GO:0004190]; cellular protein metabolic process [GO:0044267]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cellular protein metabolic process [GO:0044267]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular exosome [GO:0070062]; multivesicular body lumen [GO:0097486]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2fnta__d5p7qa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2fnub__d1e5fa___1			Proteobacteria		pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; polysaccharide biosynthetic process [GO:0000271]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	polysaccharide biosynthetic process [GO:0000271]	transsulfuration [GO:0019346]			pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d2fnub__d1sffb___1			Proteobacteria	Proteobacteria	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; polysaccharide biosynthetic process [GO:0000271]	cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	polysaccharide biosynthetic process [GO:0000271]	arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]		cytosol [GO:0005829]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]
d2fnwb__d4a2fa2__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2fnxa__d1qlla___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]
d2fny1__d1yaue___1						proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]		proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]		proteasome activator complex [GO:0008537]		
d2fny2__d3pvab___1				Firmicutes		penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]				penicillin amidase activity [GO:0008953]
d2fnya__d4qwfs___1		Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fnye__d1e3a.1__1				Proteobacteria		periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]		antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]
d2fnye__d4qz7z___1		Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fnyy__d4no1t___1		Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2fnza3_d4wleb1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d2fnzb4_d2v6mc2__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]
d2fo1a1_d3v8ob1__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; cell fate specification [GO:0001708]; dauer exit [GO:0043054]; germ-line stem cell division [GO:0042078]; nematode larval development [GO:0002119]; Notch signaling pathway [GO:0007219]; oviposition [GO:0018991]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vulval development [GO:0040026]; regulation of cell fate specification [GO:0042659]	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	cell fate specification [GO:0001708]; dauer exit [GO:0043054]; germ-line stem cell division [GO:0042078]; nematode larval development [GO:0002119]; Notch signaling pathway [GO:0007219]; oviposition [GO:0018991]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vulval development [GO:0040026]; regulation of cell fate specification [GO:0042659]	cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]
d2fo4a1_d1k5nb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2fo4b__d5xqyc___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2fo9a__d1sb1.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d2foca__d4yoja___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	extracellular space [GO:0005615]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2foda__d3ufab___1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d2foda__d4u32a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; tertiary granule lumen [GO:1904724]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; antimicrobial humoral response [GO:0019730]; cobalamin metabolic process [GO:0009235]; digestion [GO:0007586]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	antimicrobial humoral response [GO:0019730]; cobalamin metabolic process [GO:0009235]; digestion [GO:0007586]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2foea__d2ynbb___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2foha__d1uk4a___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2foha__d1zmja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d2fona3_d5k3if3__1	Viridiplantae	Metazoa	Streptophyta	Nematoda (roundworms)	peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676]	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]	fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676]	ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]	peroxisome [GO:0005777]	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]
d2fonb2_d2zafb1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	peroxisome [GO:0005777]		acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d2fowa__d2vhni1__1			Firmicutes		ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]	
d2foyb__d5dvxb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2fp1a__d5go2a___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; chorismate mutase activity [GO:0004106]; chorismate metabolic process [GO:0046417]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	chorismate metabolic process [GO:0046417]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	extracellular region [GO:0005576]		chorismate mutase activity [GO:0004106]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; chorismate mutase activity [GO:0004106]
d2fp4b2_d1c30c5__1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2fppa1_d1cqid1__1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d2fppb1_d3ufxd2__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; tricarboxylic acid cycle [GO:0006099]	succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]		ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]
d2fpsb__d3l8ea___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; histidinol-phosphatase activity [GO:0004401]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	cytosol [GO:0005829]; D,D-heptose 1,7-bisphosphate phosphatase activity [GO:0034200]; magnesium ion binding [GO:0000287]; zinc ion binding [GO:0008270]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	histidine biosynthetic process [GO:0000105]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	histidinol-phosphatase activity [GO:0004401]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]	D,D-heptose 1,7-bisphosphate phosphatase activity [GO:0034200]; magnesium ion binding [GO:0000287]; zinc ion binding [GO:0008270]
d2fpva__d3c3nd___1	Metazoa		Chordata		cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]	'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d2fq6a__d3fz6b___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; methionine biosynthetic process [GO:0009086]; transsulfuration [GO:0019346]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	methionine biosynthetic process [GO:0009086]; transsulfuration [GO:0019346]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]
d2fq9a__d2g8ea2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]; aging [GO:0007568]; brain development [GO:0007420]; cellular response to hydrogen peroxide [GO:0070301]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of vascular permeability [GO:0043117]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; response to angiotensin [GO:1990776]; response to arsenic-containing substance [GO:0046685]; self proteolysis [GO:0097264]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	aging [GO:0007568]; brain development [GO:0007420]; cellular response to hydrogen peroxide [GO:0070301]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of vascular permeability [GO:0043117]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; response to angiotensin [GO:1990776]; response to arsenic-containing substance [GO:0046685]; self proteolysis [GO:0097264]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]
d2fqda1_d2jfcf1__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2fqea1_d1bawb___1			Proteobacteria	Cyanobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	thylakoid membrane [GO:0042651]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2fqga1_d1j9sa2__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2fr1a2_d1q7ca___1			Actinobacteria	Proteobacteria	erythronolide synthase activity [GO:0047879]; phosphopantetheine binding [GO:0031177]; macrolide biosynthetic process [GO:0033068]	cytosol [GO:0005829]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]	macrolide biosynthetic process [GO:0033068]	biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]		cytosol [GO:0005829]	erythronolide synthase activity [GO:0047879]; phosphopantetheine binding [GO:0031177]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d2fr1a2_d2hmta___1			Actinobacteria	Firmicutes	erythronolide synthase activity [GO:0047879]; phosphopantetheine binding [GO:0031177]; macrolide biosynthetic process [GO:0033068]	plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; potassium ion transport [GO:0006813]	macrolide biosynthetic process [GO:0033068]	potassium ion transport [GO:0006813]		plasma membrane [GO:0005886]	erythronolide synthase activity [GO:0047879]; phosphopantetheine binding [GO:0031177]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]
d2fr3a__d3peca___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d2fr5c__d4g3mc1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]		cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d2fr5d__d5cqia1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]	cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]	cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2fr6a__d2mzza___1	Metazoa		Chordata		cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]		cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]		cytosol [GO:0005829]		cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	
d2fr6d__d4lcpb1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]	cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]		cytosol [GO:0005829]		cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]
d2fraa__d1u9xa___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d2frkx__d1v4xa___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2frma4_d3om9d2__1				Apicomplexa		L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]				L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d2frmc3_d2jhfa2__1		Metazoa		Chordata		cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d2frmc4_d4m49d2__1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]		cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2frqb__d1ewpa___1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	cysteine-type endopeptidase activity [GO:0004197]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	cysteine-type endopeptidase activity [GO:0004197]
d2fs7b__d3dszb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d2fs8a__d5eqqa1__1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; transformation of host cell by virus [GO:0019087]	proteolysis [GO:0006508]	transformation of host cell by virus [GO:0019087]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]		serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d2fs8c__d1o38a___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2fs8c__d4sgae___1	Metazoa		Chordata	Actinobacteria	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	proteolysis [GO:0006508]		collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase activity [GO:0004252]
d2fs9a__d4tpya___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2fs9c__d4yoga___1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2fsea1_d2dtgb1__1	Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	
d2fseb1_d3rkdl2__1	Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell Golgi apparatus [GO:0044177]; host cell surface [GO:0044228]; T=1 icosahedral viral capsid [GO:0039615]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell Golgi apparatus [GO:0044177]; host cell surface [GO:0044228]; T=1 icosahedral viral capsid [GO:0039615]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2fseb2_d5d7ic1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2fsed1_d5bmfl2__1	Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	
d2fsed2_d5v4mg1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d2ft7a__d3np3a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2ft9a1_d1ew3a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	extracellular region [GO:0005576]; small molecule binding [GO:0036094]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]	lipid binding [GO:0008289]	small molecule binding [GO:0036094]
d2ft9a1_d3fa9b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	lipid binding [GO:0008289]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d2ftab__d4knua1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ftba__d5dg4b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]		epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	lipid binding [GO:0008289]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d2ftqa__d1bsfb___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytosol [GO:0005829]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytosol [GO:0005829]	cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d2ftsa1_d2fu3b1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]
d2ftsa3_d1o8qb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; auxin-activated signaling pathway [GO:0009734]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; response to metal ion [GO:0010038]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	auxin-activated signaling pathway [GO:0009734]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; response to metal ion [GO:0010038]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]	ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]
d2fu3a1_d2nqsa1__1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d2fu3a3_d2nqmb3__1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d2fu3b3_d4lhbb___1	Metazoa		Chordata	Euryarchaeota	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	ATP binding [GO:0005524]; molybdopterin adenylyltransferase activity [GO:0061598]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]	ATP binding [GO:0005524]; molybdopterin adenylyltransferase activity [GO:0061598]
d2fu6a__d1l9yb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	beta-lactamase activity [GO:0008800]; metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; metal ion binding [GO:0046872]
d2fu7b__d5ew0b___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2fuaa__d1e4bp___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]; pentose catabolic process [GO:0019323]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]	aldehyde-lyase activity [GO:0016832]; L-fuculose-phosphate aldolase activity [GO:0008738]; zinc ion binding [GO:0008270]
d2fuba1_d1n3rl___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d2fuba2_d1gtpc___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d2fug91_d1vldv2__1			Deinococcus-Thermus		plasma membrane [GO:0005886]; quinone binding [GO:0048038]				plasma membrane [GO:0005886]		quinone binding [GO:0048038]	
d2fugb1_d1nw2d___1			Deinococcus-Thermus	Firmicutes	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	plasma membrane [GO:0005886]	cell [GO:0005623]	quinone binding [GO:0048038]	protein disulfide oxidoreductase activity [GO:0015035]
d2fugh1_d1ekga___1		Metazoa	Deinococcus-Thermus	Chordata	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]		adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	quinone binding [GO:0048038]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]
d2fv0b__d5m7ia___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; polysaccharide catabolic process [GO:0000272]	catalytic activity [GO:0003824]	polysaccharide catabolic process [GO:0000272]		cytoplasm [GO:0005737]		hydrolase activity, acting on glycosyl bonds [GO:0016798]	catalytic activity [GO:0003824]
d2fv1a__d1kfgb1__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	cytoplasm [GO:0005737]		hydrolase activity, acting on glycosyl bonds [GO:0016798]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d2fv1b__d1l2af___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	hydrolase activity, acting on glycosyl bonds [GO:0016798]	cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity (reducing end) [GO:0102252]; metal ion binding [GO:0046872]
d2fv5b__d1d7xa___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d2fvea__d2kooa___1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast [GO:0009507]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]	fatty acid biosynthetic process [GO:0006633]		chloroplast [GO:0009507]	cytoplasm [GO:0005737]	phosphopantetheine binding [GO:0031177]	acyl carrier activity [GO:0000036]
d2fvhc__d4furb___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d2fvlc__d4famb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; bile acid transmembrane transporter activity [GO:0015125]; chlordecone reductase activity [GO:0047743]; electron transfer activity [GO:0009055]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; retinal dehydrogenase activity [GO:0001758]; steroid dehydrogenase activity [GO:0016229]; androgen metabolic process [GO:0008209]; bile acid and bile salt transport [GO:0015721]; bile acid biosynthetic process [GO:0006699]; cellular response to jasmonic acid stimulus [GO:0071395]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]; 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; prostaglandin-F synthase activity [GO:0047017]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]	androgen metabolic process [GO:0008209]; bile acid and bile salt transport [GO:0015721]; bile acid biosynthetic process [GO:0006699]; cellular response to jasmonic acid stimulus [GO:0071395]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]	cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; bile acid transmembrane transporter activity [GO:0015125]; chlordecone reductase activity [GO:0047743]; electron transfer activity [GO:0009055]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; retinal dehydrogenase activity [GO:0001758]; steroid dehydrogenase activity [GO:0016229]	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin-F synthase activity [GO:0047017]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]
d2fvna1_d4xoba1__1			Proteobacteria	Proteobacteria		host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d2fw1a__d4grdc___1			Proteobacteria	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]
d2fw1b__d4grda___1			Proteobacteria	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]
d2fw2c__d1xnwa1__1	Metazoa		Chordata	Actinobacteria	nucleus [GO:0005634]; histone acetyltransferase activity [GO:0004402]; transcription corepressor activity [GO:0003714]; spermatogenesis [GO:0007283]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	spermatogenesis [GO:0007283]	fatty acid biosynthetic process [GO:0006633]	nucleus [GO:0005634]	acetyl-CoA carboxylase complex [GO:0009317]	histone acetyltransferase activity [GO:0004402]; transcription corepressor activity [GO:0003714]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]
d2fw2e__d2zl0m___1	Metazoa		Chordata	Proteobacteria	nucleus [GO:0005634]; histone acetyltransferase activity [GO:0004402]; transcription corepressor activity [GO:0003714]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	spermatogenesis [GO:0007283]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	histone acetyltransferase activity [GO:0004402]; transcription corepressor activity [GO:0003714]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d2fw4a__d5jn9c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	anchored component of external side of plasma membrane [GO:0031362]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell surface [GO:0009986]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	bicarbonate transport [GO:0015701]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	anchored component of external side of plasma membrane [GO:0031362]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell surface [GO:0009986]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2fw6b__d3rg8g___1			Proteobacteria	Spirochaetes	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]
d2fw9a__d4b4ke___1			Proteobacteria	Firmicutes	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]
d2fw9b__d5c5da___1			Proteobacteria	Spirochaetes	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]
d2fwab__d2fw8a___1			Proteobacteria	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d2fwba__d3rg8c___1			Proteobacteria	Spirochaetes	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]
d2fwea2_d5hr1a___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]; electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2fwib__d4ay3d___1			Proteobacteria	Firmicutes	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]
d2fwja__d3lp6a___1			Proteobacteria	Actinobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d2fwlb__d2hx8b___1			Deinococcus-Thermus	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2fwob__d1sjeb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d2fwpb__d4b4ka___1			Proteobacteria	Firmicutes	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]
d2fwra2_d4mitb___1			Euryarchaeota		ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]	plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; small GTPase mediated signal transduction [GO:0007264]		small GTPase mediated signal transduction [GO:0007264]		plasma membrane [GO:0005886]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d2fwrc2_d4d72a1__1			Euryarchaeota	Firmicutes	ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]	blood-group-substance endo-1,4-beta-galactosidase activity [GO:0033929]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]	blood-group-substance endo-1,4-beta-galactosidase activity [GO:0033929]
d2fwwc__d1xuga___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2fwya__d1z5aa3__1	Metazoa		Chordata	Crenarchaeota	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]
d2fx2a__d1akua___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2fx2a__d2z9db___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; azobenzene reductase activity [GO:0050446]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor [GO:0016652]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; response to oxidative stress [GO:0006979]		response to oxidative stress [GO:0006979]		cytosol [GO:0005829]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	azobenzene reductase activity [GO:0050446]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor [GO:0016652]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]
d2fx7h1_d1jgdb1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2fx7l1_d4zfol1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	endomembrane system [GO:0012505]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; lymphocyte homeostasis [GO:0002260]; multicellular organism development [GO:0007275]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; lymphocyte homeostasis [GO:0002260]; multicellular organism development [GO:0007275]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	endomembrane system [GO:0012505]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	structural molecule activity [GO:0005198]	signaling receptor activity [GO:0038023]
d2fx7l1_d5f97g1__1				Proteobacteria	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d2fx8h1_d5hvhb1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; blood coagulation [GO:0007596]; cellular response to glucose stimulus [GO:0071333]; fibrinolysis [GO:0042730]; liver regeneration [GO:0097421]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of plasminogen activation [GO:0010757]; positive regulation of extracellular matrix constituent secretion [GO:0003331]; proteolysis [GO:0006508]; regulation of complement activation [GO:0030449]; response to drug [GO:0042493]; response to heat [GO:0009408]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; cellular response to glucose stimulus [GO:0071333]; fibrinolysis [GO:0042730]; liver regeneration [GO:0097421]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of plasminogen activation [GO:0010757]; positive regulation of extracellular matrix constituent secretion [GO:0003331]; proteolysis [GO:0006508]; regulation of complement activation [GO:0030449]; response to drug [GO:0042493]; response to heat [GO:0009408]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	structural molecule activity [GO:0005198]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2fx8j2_d3sdac1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	structural molecule activity [GO:0005198]	
d2fx8k2_d5xajb1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d2fx8l1_d2oqje2__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d2fx8l2_d4huvd2__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2fx8l2_d5mhrl1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d2fx8m2_d4hwbl1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; interleukin-13 receptor complex [GO:0005898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-2 binding [GO:0019976]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; interleukin-13 receptor complex [GO:0005898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	structural molecule activity [GO:0005198]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-2 binding [GO:0019976]
d2fx8n1_d1mhph1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	structural molecule activity [GO:0005198]	collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]
d2fx8o2_d3fb5b1__1				Actinobacteria	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	voltage-gated potassium channel complex [GO:0008076]	structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d2fx9h1_d1j5oh2__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	structural molecule activity [GO:0005198]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2fx9h1_d3qeua1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	structural molecule activity [GO:0005198]	
d2fx9h2_d4pjbg1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2fx9l1_d1jnlh1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2fx9l2_d3qxua___1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d2fx9m1_d1jnnl1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2fx9m1_d4s1df1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d2fx9m2_d2iptl1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	metal ion binding [GO:0046872]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]
d2fxda__d1kjha___1					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2fxeb__d4m8xb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]
d2fxia__d1xwwa___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; extracellular exosome [GO:0070062]; acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]	response to arsenic-containing substance [GO:0046685]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; extracellular exosome [GO:0070062]	arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]	acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]
d2fxla2_d1is7e___1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]
d2fxra__d3su6a1__1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2fxrb__d1rtl.1__1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2fxrc__d4wh8a1__1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2fxrd__d3t29a___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2fxsa2_d4wuca1__1	Fungi		Ascomycota	Proteobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; DNA-dependent ATPase activity [GO:0008094]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d2fxta1_d1nwwb___1	Fungi		Ascomycota	Actinobacteria	extrinsic component of mitochondrial inner membrane [GO:0031314]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; PAM complex, Tim23 associated import motor [GO:0001405]; TIM23 mitochondrial import inner membrane translocase complex [GO:0005744]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; protein binding, bridging [GO:0030674]; protein import into mitochondrial matrix [GO:0030150]	limonene-1,2-epoxide hydrolase activity [GO:0018744]	protein import into mitochondrial matrix [GO:0030150]		extrinsic component of mitochondrial inner membrane [GO:0031314]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; PAM complex, Tim23 associated import motor [GO:0001405]; TIM23 mitochondrial import inner membrane translocase complex [GO:0005744]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; protein binding, bridging [GO:0030674]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d2fxua2_d3bf3b2__1	Metazoa		Chordata	Thermotogae	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	coenzyme A biosynthetic process [GO:0015937]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cytoplasm [GO:0005737]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d2fy2a2_d1l5ac2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleus [GO:0005634]; presynapse [GO:0098793]; choline O-acetyltransferase activity [GO:0004102]; acetylcholine biosynthetic process [GO:0008292]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; phosphatidylcholine biosynthetic process [GO:0006656]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; enterobactin synthetase complex [GO:0009366]; 2,3-dihydroxybenzoate-serine ligase activity [GO:0047527]; acid-ammonia (or amide) ligase activity [GO:0016880]; phosphopantetheine binding [GO:0031177]; amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; enterobactin biosynthetic process [GO:0009239]; secondary metabolite biosynthetic process [GO:0044550]; siderophore biosynthetic process [GO:0019290]	acetylcholine biosynthetic process [GO:0008292]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; phosphatidylcholine biosynthetic process [GO:0006656]	amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; enterobactin biosynthetic process [GO:0009239]; secondary metabolite biosynthetic process [GO:0044550]; siderophore biosynthetic process [GO:0019290]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleus [GO:0005634]; presynapse [GO:0098793]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; enterobactin synthetase complex [GO:0009366]	choline O-acetyltransferase activity [GO:0004102]	2,3-dihydroxybenzoate-serine ligase activity [GO:0047527]; acid-ammonia (or amide) ligase activity [GO:0016880]; phosphopantetheine binding [GO:0031177]
d2fy5a2_d1pd5d___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleus [GO:0005634]; presynapse [GO:0098793]; choline O-acetyltransferase activity [GO:0004102]; acetylcholine biosynthetic process [GO:0008292]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; phosphatidylcholine biosynthetic process [GO:0006656]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	acetylcholine biosynthetic process [GO:0008292]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; phosphatidylcholine biosynthetic process [GO:0006656]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleus [GO:0005634]; presynapse [GO:0098793]		choline O-acetyltransferase activity [GO:0004102]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d2fy6a1_d4fh8a1__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cell [GO:0005623]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; cell redox homeostasis [GO:0045454]; cellular protein modification process [GO:0006464]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular protein modification process [GO:0006464]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]	peroxiredoxin activity [GO:0051920]
d2fy8a1_d2hmsd___1			Euryarchaeota	Firmicutes	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	plasma membrane [GO:0005886]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]
d2fy8a1_d5vl0d2__1		Metazoa	Euryarchaeota	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	potassium ion transport [GO:0006813]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d2fy8e1_d4ei2m1__1			Euryarchaeota	Euryarchaeota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2fy8f1_d1h0ka2__1		Fungi	Euryarchaeota	Ascomycota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	potassium ion transport [GO:0006813]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	mitochondrion [GO:0005739]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]
d2fy8f1_d4ro0h1__1			Euryarchaeota	Euryarchaeota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2fyca__d2cjla___1	Metazoa		Chordata	Actinobacteria	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	chitinase activity [GO:0004568]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]		alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	chitinase activity [GO:0004568]; metal ion binding [GO:0046872]
d2fyca__d2mefa___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2fycc__d2f47a___1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	host cell cytoplasm [GO:0030430]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	lysozyme activity [GO:0003796]
d2fydc__d216lb___1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	host cell cytoplasm [GO:0030430]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	lysozyme activity [GO:0003796]
d2fyea__d5w8tc2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2fyib2_d3tcff___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; positive regulation of sulfur utilization [GO:0045883]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	positive regulation of sulfur utilization [GO:0045883]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]
d2fyic2_d4nwda___1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; positive regulation of sulfur utilization [GO:0045883]	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]	positive regulation of sulfur utilization [GO:0045883]	chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]		axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2fyic2_d6eqzd1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; positive regulation of sulfur utilization [GO:0045883]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	positive regulation of sulfur utilization [GO:0045883]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d2fyid2_d1jnfa2__1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; positive regulation of sulfur utilization [GO:0045883]	cell [GO:0005623]; extracellular space [GO:0005615]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; cellular iron ion homeostasis [GO:0006879]	positive regulation of sulfur utilization [GO:0045883]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; extracellular space [GO:0005615]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]
d2fymc2_d3zvia1__1			Proteobacteria	Firmicutes	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]; glutamate catabolic process via L-citramalate [GO:0019553]	glycolytic process [GO:0006096]	glutamate catabolic process via L-citramalate [GO:0019553]	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]
d2fymd2_d4izga1__1			Proteobacteria	Proteobacteria	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	metal ion binding [GO:0046872]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; amino-acid betaine catabolic process [GO:0006579]	glycolytic process [GO:0006096]	amino-acid betaine catabolic process [GO:0006579]	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	metal ion binding [GO:0046872]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d2fymf1_d3b97b2__1		Metazoa	Proteobacteria	Chordata	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d2fymf2_d4gghc1__1			Proteobacteria	Proteobacteria	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	glycolytic process [GO:0006096]	cellular amino acid catabolic process [GO:0009063]	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]
d2fyua1_d3h1ha1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d2fyva3_d3czna3__1	Metazoa	Metazoa	Arthropoda	Arthropoda	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d2fyxb2_d2viha1__1			Deinococcus-Thermus	Proteobacteria	DNA binding [GO:0003677]; transposase activity [GO:0004803]; transposition, DNA-mediated [GO:0006313]	DNA binding [GO:0003677]; transposase activity [GO:0004803]; transposition, DNA-mediated [GO:0006313]	transposition, DNA-mediated [GO:0006313]	transposition, DNA-mediated [GO:0006313]			DNA binding [GO:0003677]; transposase activity [GO:0004803]	DNA binding [GO:0003677]; transposase activity [GO:0004803]
d2fyya2_d1fg2g2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2fyya2_d4z7wd1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	nutrient reservoir activity [GO:0045735]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	nutrient reservoir activity [GO:0045735]
d2fyyb__d5vphc1__1	Metazoa	Metazoa	Chordata	Arthropoda	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cysteine-type peptidase activity [GO:0008234]
d2fz1c__d1auya___1					T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]			T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d2fz1c__d2rs3.1__1					T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2fz2a__d1w39c___1					T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]			T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d2fz2a__d4ceya___1					T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2fz2b__d1ddla___1					T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]			T=3 icosahedral viral capsid [GO:0039617]	viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d2fz2c__d1b35.1__1					T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]; structural molecule activity [GO:0005198]			T=3 icosahedral viral capsid [GO:0039617]	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d2fz3a1_d4fqil1__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d2fz5a1_d2qx8b___1		Metazoa	Firmicutes	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d2fz6b__d2b97a___1	Fungi	Fungi	Ascomycota	Ascomycota	cell wall [GO:0005618]; extracellular region [GO:0005576]	extracellular region [GO:0005576]; spore wall [GO:0031160]			cell wall [GO:0005618]; extracellular region [GO:0005576]	extracellular region [GO:0005576]; spore wall [GO:0031160]		
d2fzcc1_d1rahc2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2fzcc2_d2fg7d2__1			Proteobacteria	Bacteroidetes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]
d2fzcc2_d3r7fc2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d2fzea2_d2xxjd1__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]	L-lactate dehydrogenase activity [GO:0004459]
d2fzfa1_d2bkck___1			Euryarchaeota	Firmicutes	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2fzgc1_d4e2fi2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2fzia__d1dhjb___1	Fungi		Ascomycota	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d2fzja__d3frax___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d2fzja__d4m2xg___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]
d2fzka1_d4kh1a1__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	
d2fzkb1_d1radb1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2fzkc1_d1raaa2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2fzkc2_d3l05a1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]
d2fzra1_d2rvja1__1		Metazoa		Chordata		nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA processing [GO:0006397]; regulation of inner ear auditory receptor cell fate specification [GO:0042669]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]		fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA processing [GO:0006397]; regulation of inner ear auditory receptor cell fate specification [GO:0042669]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]		nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		mRNA binding [GO:0003729]
d2fzvb2_d4qodb___1		Metazoa	Proteobacteria	Chordata	azobenzene reductase activity [GO:0050446]; FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	azobenzene reductase activity [GO:0050446]; FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d2g00a__d4wmec___1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]
d2g0ed1_d5j1ua1__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d2g0fa__d3hy2b___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]; cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]	cytosol [GO:0005829]	disulfide oxidoreductase activity [GO:0015036]	ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]
d2g0fa__d4polc1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	disulfide oxidoreductase activity [GO:0015036]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d2g0ka__d2cbqa___1			Actinobacteria	Actinobacteria	DNA binding [GO:0003677]; defense response to bacterium [GO:0042742]	DNA binding [GO:0003677]; defense response to bacterium [GO:0042742]	defense response to bacterium [GO:0042742]	defense response to bacterium [GO:0042742]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2g0na1_d3b13b___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; calcium-dependent protein binding [GO:0048306]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cerebral cortex GABAergic interneuron development [GO:0021894]; establishment or maintenance of cell polarity [GO:0007163]; homeostasis of number of cells within a tissue [GO:0048873]; intracellular signal transduction [GO:0035556]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of neuron maturation [GO:0014041]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; synaptic transmission, GABAergic [GO:0051932]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; histone deacetylase binding [GO:0042826]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cell-matrix adhesion [GO:0007160]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cerebral cortex GABAergic interneuron development [GO:0021894]; establishment or maintenance of cell polarity [GO:0007163]; homeostasis of number of cells within a tissue [GO:0048873]; intracellular signal transduction [GO:0035556]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of neuron maturation [GO:0014041]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; synaptic transmission, GABAergic [GO:0051932]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cell cortex [GO:0005938]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]	calcium-dependent protein binding [GO:0048306]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein kinase binding [GO:0019901]	ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; histone deacetylase binding [GO:0042826]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]
d2g0va__d3lhbg___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2g0ya__d3n90a1__1		Viridiplantae	Cyanobacteria	Streptophyta	thylakoid lumen [GO:0031977]	chloroplast [GO:0009507]; chloroplast thylakoid [GO:0009534]; chloroplast thylakoid lumen [GO:0009543]; chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; thylakoid [GO:0009579]; thylakoid lumen [GO:0031977]			thylakoid lumen [GO:0031977]	chloroplast [GO:0009507]; chloroplast thylakoid [GO:0009534]; chloroplast thylakoid lumen [GO:0009543]; chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; thylakoid [GO:0009579]; thylakoid lumen [GO:0031977]		
d2g14a__d1mwca___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2g19a__d5pl6a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; 2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; enzyme binding [GO:0019899]; ferrous iron binding [GO:0008198]; L-ascorbic acid binding [GO:0031418]; peptidyl-proline 4-dioxygenase activity [GO:0031545]; peptidyl-proline dioxygenase activity [GO:0031543]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; oxygen homeostasis [GO:0032364]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of angiogenesis [GO:0045765]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; response to nitric oxide [GO:0071731]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; oxygen homeostasis [GO:0032364]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of angiogenesis [GO:0045765]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; response to nitric oxide [GO:0071731]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; enzyme binding [GO:0019899]; ferrous iron binding [GO:0008198]; L-ascorbic acid binding [GO:0031418]; peptidyl-proline 4-dioxygenase activity [GO:0031545]; peptidyl-proline dioxygenase activity [GO:0031543]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d2g1ia3_d3fsjx1__1				Proteobacteria		benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2g1ic2_d3glsf___1		Metazoa		Chordata		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d2g1id2_d6eqsc1__1		Metazoa		Chordata		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-glutaryllysine deglutarylase activity [GO:0061697]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; zinc ion binding [GO:0008270]; mitochondrion organization [GO:0007005]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine demalonylation [GO:0036047]; peptidyl-lysine desuccinylation [GO:0036049]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]; protein deglutarylation [GO:0061698]; protein demalonylation [GO:0036046]; protein desuccinylation [GO:0036048]; regulation of ketone biosynthetic process [GO:0010566]; response to nutrient levels [GO:0031667]		mitochondrion organization [GO:0007005]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine demalonylation [GO:0036047]; peptidyl-lysine desuccinylation [GO:0036049]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]; protein deglutarylation [GO:0061698]; protein demalonylation [GO:0036046]; protein desuccinylation [GO:0036048]; regulation of ketone biosynthetic process [GO:0010566]; response to nutrient levels [GO:0031667]		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-glutaryllysine deglutarylase activity [GO:0061697]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; zinc ion binding [GO:0008270]
d2g1nb__d4cpsb___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2g1oa__d3jvya___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2g1ob__d2ceja___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]
d2g1rb__d5p3ia___1	Metazoa	Fungi	Chordata	Ascomycota	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]
d2g1sa__d2i0aa___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]
d2g1sb__d2z4oa___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2g1ua__d4aj4c1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2g1yb__d5ivqa___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]
d2g1yb__d5p2na___1	Metazoa	Fungi	Chordata	Ascomycota	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]
d2g20a__d2f3ka___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2g20b__d5ivqb___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]
d2g20b__d5p7ia___1	Metazoa	Fungi	Chordata	Ascomycota	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]
d2g22b__d5p1xa___1	Metazoa	Fungi	Chordata	Ascomycota	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]
d2g25a3_d1trkb3__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]	pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d2g25b2_d1trkb1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]	pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d2g28a3_d1b0pb3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	glycolytic process [GO:0006096]	electron transport chain [GO:0022900]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d2g28b3_d2c3yb3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	glycolytic process [GO:0006096]	electron transport chain [GO:0022900]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d2g2la__d1d5ga___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]
d2g2la__d4nmpb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]	ion channel binding [GO:0044325]
d2g2na__d5cr1b___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	periplasmic space [GO:0042597]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d2g2nd__d3iwuf___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	periplasmic space [GO:0042597]	peroxisome [GO:0005777]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d2g2nd__d4tlua___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	periplasmic space [GO:0042597]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d2g2pc__d2h6ug___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	periplasmic space [GO:0042597]	peroxisome [GO:0005777]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d2g2ra2_d5drxb2__1	Metazoa		Chordata		extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]		extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]			
d2g2rl1_d5ldnl1__1	Metazoa		Chordata		extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]	host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]; viral capsid [GO:0019028]; structural molecule activity [GO:0005198]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]	adaptive immune response [GO:0002250]	microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]	host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]; viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d2g30a1_d1na8a1__1	Metazoa	Metazoa	Chordata	Chordata	AP-2 adaptor complex [GO:0030122]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]; clathrin binding [GO:0030276]; protein-containing complex binding [GO:0044877]; signal sequence binding [GO:0005048]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; coronary vasculature development [GO:0060976]; ephrin receptor signaling pathway [GO:0048013]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; membrane organization [GO:0061024]; negative regulation of neuron death [GO:1901215]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein localization to membrane [GO:1905477]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; regulation of defense response to virus by virus [GO:0050690]; synaptic vesicle endocytosis [GO:0048488]; ventricular septum development [GO:0003281]; vesicle-mediated transport [GO:0016192]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; coronary vasculature development [GO:0060976]; ephrin receptor signaling pathway [GO:0048013]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; membrane organization [GO:0061024]; negative regulation of neuron death [GO:1901215]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein localization to membrane [GO:1905477]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; regulation of defense response to virus by virus [GO:0050690]; synaptic vesicle endocytosis [GO:0048488]; ventricular septum development [GO:0003281]; vesicle-mediated transport [GO:0016192]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	AP-2 adaptor complex [GO:0030122]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	clathrin binding [GO:0030276]; protein-containing complex binding [GO:0044877]; signal sequence binding [GO:0005048]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]
d2g38a1_d4kxrb___1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]	cell surface [GO:0009986]; extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	cell wall [GO:0005618]; extracellular region [GO:0005576]	cell surface [GO:0009986]; extracellular region [GO:0005576]		
d2g38b1_d4w4la___1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]	cell surface [GO:0009986]; extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	cell wall [GO:0005618]; extracellular region [GO:0005576]	cell surface [GO:0009986]; extracellular region [GO:0005576]		
d2g3ha__d1b86c___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]; oxygen transport [GO:0015671]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxygen transport [GO:0015671]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2g3ja__d1e6xm___1		Viridiplantae	Actinobacteria	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		vacuole [GO:0005773]	endo-1,4-beta-xylanase activity [GO:0031176]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]
d2g3pa1_d4eo1a___1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; pathogenesis [GO:0009405]; viral entry into host cell via pilus basal pore [GO:0039668]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell via pilus retraction [GO:0039667]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; pathogenesis [GO:0009405]; viral entry into host cell via pilus basal pore [GO:0039668]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell via pilus retraction [GO:0039667]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]		
d2g3qb__d2c7nd1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP-dependent protein binding [GO:0043008]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; ascospore formation [GO:0030437]; modification-dependent protein catabolic process [GO:0019941]; protein deubiquitination [GO:0016579]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	ascospore formation [GO:0030437]; modification-dependent protein catabolic process [GO:0019941]; protein deubiquitination [GO:0016579]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP-dependent protein binding [GO:0043008]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2g45b__d5ms5b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d2g46a__d1n3ja___1					identical protein binding [GO:0042802]; methyltransferase activity [GO:0008168]	identical protein binding [GO:0042802]; methyltransferase activity [GO:0008168]					identical protein binding [GO:0042802]; methyltransferase activity [GO:0008168]	identical protein binding [GO:0042802]; methyltransferase activity [GO:0008168]
d2g4ca1_d1adyb1__1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	histidyl-tRNA aminoacylation [GO:0006427]	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]
d2g4ca1_d4p3nc2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	threonyl-tRNA aminoacylation [GO:0006435]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]
d2g4cb1_d4eo4c2__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; mitochondrial threonyl-tRNA aminoacylation [GO:0070159]; threonyl-tRNA aminoacylation [GO:0006435]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	mitochondrial threonyl-tRNA aminoacylation [GO:0070159]; threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]
d2g4da1_d5aekw___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d2g4db__d5dpwi___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; nucleolus [GO:0005730]; metal ion binding [GO:0046872]; autophagy [GO:0006914]; intracellular signal transduction [GO:0035556]; lysosome localization [GO:0032418]; positive regulation of bone resorption [GO:0045780]; positive regulation of ruffle assembly [GO:1900029]; protein transport [GO:0015031]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	autophagy [GO:0006914]; intracellular signal transduction [GO:0035556]; lysosome localization [GO:0032418]; positive regulation of bone resorption [GO:0045780]; positive regulation of ruffle assembly [GO:1900029]; protein transport [GO:0015031]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; nucleolus [GO:0005730]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]	metal ion binding [GO:0046872]
d2g4fb__d1f49d5__1			Actinobacteria		endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]				endo-1,4-beta-xylanase activity [GO:0031176]	
d2g4ia__d1wuvj___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]		negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]
d2g4ja__d5nh6b___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d2g4na__d5njsa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2g4nb__d5b5ja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2g4nd__d1ir9a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2g4ne__d1cv5a___1	Metazoa		Chordata		extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]	lysozyme activity [GO:0003796]
d2g4ne__d4h9ea___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2g4nf__d1b2ka___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2g4oc2_d5grlb___1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; ATP binding [GO:0005524]; isocitrate dehydrogenase (NAD+) activity [GO:0004449]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	carbohydrate metabolic process [GO:0005975]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	ATP binding [GO:0005524]; isocitrate dehydrogenase (NAD+) activity [GO:0004449]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d2g4za__d5i0la___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d2g51a__d1azza___1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	outer membrane-bounded periplasmic space [GO:0030288]; serine-type endopeptidase inhibitor activity [GO:0004867]			extracellular region [GO:0005576]	outer membrane-bounded periplasmic space [GO:0030288]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase inhibitor activity [GO:0004867]
d2g5fa1_d1i1qa___1			Actinobacteria	Proteobacteria	plasma membrane [GO:0005886]; chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]; isochorismate synthase activity [GO:0008909]; magnesium ion binding [GO:0000287]; oxo-acid-lyase activity [GO:0016833]; cellular response to iron ion starvation [GO:0010106]; response to host immune response [GO:0052572]; salicylic acid biosynthetic process [GO:0009697]; siderophore biosynthetic process from catechol [GO:0019540]	anthranilate phosphoribosyltransferase activity [GO:0004048]; anthranilate synthase activity [GO:0004049]; magnesium ion binding [GO:0000287]; glutamine metabolic process [GO:0006541]; phenazine biosynthetic process [GO:0002047]; tryptophan biosynthetic process [GO:0000162]	cellular response to iron ion starvation [GO:0010106]; response to host immune response [GO:0052572]; salicylic acid biosynthetic process [GO:0009697]; siderophore biosynthetic process from catechol [GO:0019540]	glutamine metabolic process [GO:0006541]; phenazine biosynthetic process [GO:0002047]; tryptophan biosynthetic process [GO:0000162]	plasma membrane [GO:0005886]		chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]; isochorismate synthase activity [GO:0008909]; magnesium ion binding [GO:0000287]; oxo-acid-lyase activity [GO:0016833]	anthranilate phosphoribosyltransferase activity [GO:0004048]; anthranilate synthase activity [GO:0004049]; magnesium ion binding [GO:0000287]
d2g5ha__d1mt5e___1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]; regulation of translational fidelity [GO:0006450]; translation [GO:0006412]	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]	regulation of translational fidelity [GO:0006450]; translation [GO:0006412]	fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]	ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]	acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]
d2g5la__d4ggra___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2g5tb2_d5a71a___1	Metazoa	Fungi	Chordata	Basidiomycota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	triglyceride lipase activity [GO:0004806]
d2g5xa__d3hiqb1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	RNA glycosylase activity [GO:0030597]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			RNA glycosylase activity [GO:0030597]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2g60h3_d4jkwa1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor binding [GO:0005102]; activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; cytokine secretion [GO:0050663]; interferon-gamma secretion [GO:0072643]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; cytokine secretion [GO:0050663]; interferon-gamma secretion [GO:0072643]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		signaling receptor binding [GO:0005102]
d2g60l1_d3jwdo2__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d2g60l2_d1a9db1__1												
d2g60l2_d4pjfh1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2g63b2_d4re5b2__1	Metazoa		Chordata	Crenarchaeota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	serine-type peptidase activity [GO:0008236]
d2g69a__d1d4jb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2g6zb__d1q1ma___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; activation of MAPK activity [GO:0000187]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; MAPK cascade [GO:0000165]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	activation of MAPK activity [GO:0000187]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; MAPK cascade [GO:0000165]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2g6zc1_d5bzxb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; activation of MAPK activity [GO:0000187]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; MAPK cascade [GO:0000165]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; ubiquitin-specific protease binding [GO:1990381]; adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	activation of MAPK activity [GO:0000187]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; MAPK cascade [GO:0000165]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381]
d2g74a__d1pvfa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]
d2g75a2_d1kpvb___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2g75b1_d2ywya___1		Metazoa		Chordata								
d2g7ba__d1d2ua___1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	vasodilation [GO:0042311]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d2g7mc1_d3r7lb2__1			Bacteroidetes	Firmicutes	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cellular amino acid metabolic process [GO:0006520]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d2g7md2_d4amuc2__1			Bacteroidetes	Tenericutes	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	cellular amino acid metabolic process [GO:0006520]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]		cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d2g7me1_d1otha2__1		Metazoa	Bacteroidetes	Chordata	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; phosphate ion binding [GO:0042301]; phospholipid binding [GO:0005543]; ammonia homeostasis [GO:0097272]; anion homeostasis [GO:0055081]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; liver development [GO:0001889]; midgut development [GO:0007494]; ornithine catabolic process [GO:0006593]; protein homotrimerization [GO:0070207]; response to biotin [GO:0070781]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cellular amino acid metabolic process [GO:0006520]	ammonia homeostasis [GO:0097272]; anion homeostasis [GO:0055081]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]; liver development [GO:0001889]; midgut development [GO:0007494]; ornithine catabolic process [GO:0006593]; protein homotrimerization [GO:0070207]; response to biotin [GO:0070781]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; phosphate ion binding [GO:0042301]; phospholipid binding [GO:0005543]
d2g7mx1_d3r7fc1__1			Bacteroidetes	Firmicutes	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cellular amino acid metabolic process [GO:0006520]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d2g7ya__d3ltwa___1	Metazoa		Chordata	Actinobacteria	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	acetyltransferase activity [GO:0016407]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	acetyltransferase activity [GO:0016407]
d2g82a2_d4gpd12__1		Metazoa	Deinococcus-Thermus	Arthropoda	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2g82c2_d1gyqa2__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	glycosome [GO:0020015]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2g82q2_d1nqaq2__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2g82r2_d1u1ib2__1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	integral component of membrane [GO:0016021]; inositol-3-phosphate synthase activity [GO:0004512]; nucleotide binding [GO:0000166]; inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	inositol-3-phosphate synthase activity [GO:0004512]; nucleotide binding [GO:0000166]
d2g84a1_d2z3hc___1		Fungi	Proteobacteria	Ascomycota	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]			hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d2g89a__d1ajma___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	thymidylate synthase activity [GO:0004799]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]
d2g8ma__d1bkpa___1				Firmicutes		cytosol [GO:0005829]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]		dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]		cytosol [GO:0005829]		thymidylate synthase activity [GO:0004799]
d2g8na__d5k09t___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	phenylethanolamine N-methyltransferase activity [GO:0004603]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d2g8rb__d3ljda___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]		endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]
d2g8xb__d5by6c___1		Metazoa	Proteobacteria	Nematoda (roundworms)	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]	cytosol [GO:0005829]		magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d2g94d__d2aqub___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2g98a1_d2v2ua1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; camera-type eye development [GO:0043010]; eye development [GO:0001654]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]	camera-type eye development [GO:0043010]; eye development [GO:0001654]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d2g9ha1_d1q0xh1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	
d2g9yb__d1hqaa___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]
d2ga0a__d1f1mc___1			Spirochaetes	Spirochaetes	cell outer membrane [GO:0009279]	cell outer membrane [GO:0009279]; metal ion binding [GO:0046872]			cell outer membrane [GO:0009279]	cell outer membrane [GO:0009279]		metal ion binding [GO:0046872]
d2ga0c__d1f1mb___1			Spirochaetes	Spirochaetes	cell outer membrane [GO:0009279]	cell outer membrane [GO:0009279]; metal ion binding [GO:0046872]			cell outer membrane [GO:0009279]	cell outer membrane [GO:0009279]		metal ion binding [GO:0046872]
d2ga0f__d1ggqd___1			Spirochaetes	Spirochaetes	cell outer membrane [GO:0009279]	external side of cell outer membrane [GO:0031240]; membrane [GO:0016020]			cell outer membrane [GO:0009279]	external side of cell outer membrane [GO:0031240]; membrane [GO:0016020]		
d2ga0g__d1ggqb___1			Spirochaetes	Spirochaetes	cell outer membrane [GO:0009279]	external side of cell outer membrane [GO:0031240]; membrane [GO:0016020]			cell outer membrane [GO:0009279]	external side of cell outer membrane [GO:0031240]; membrane [GO:0016020]		
d2ga5a1_d3t3tb___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron chaperone activity [GO:0034986]; cellular iron ion homeostasis [GO:0006879]; glutathione metabolic process [GO:0006749]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; mitochondrion organization [GO:0007005]; response to iron(II) ion [GO:0010040]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	cellular iron ion homeostasis [GO:0006879]; glutathione metabolic process [GO:0006749]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; mitochondrion organization [GO:0007005]; response to iron(II) ion [GO:0010040]; response to oxidative stress [GO:0006979]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	cell [GO:0005623]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron chaperone activity [GO:0034986]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]
d2gabb__d2h1xa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d2gasa__d4uvda___1	Viridiplantae		Streptophyta	Actinobacteria	2'-hydroxyisoflavone reductase activity [GO:0047526]; defense response [GO:0006952]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	defense response [GO:0006952]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]	2'-hydroxyisoflavone reductase activity [GO:0047526]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d2gaua1_d3e6ba2__1			Bacteroidetes	Firmicutes	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2gazb__d5v7je1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d2gb2a__d3t71c3__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]			periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2gb8b__d1iqcd2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	periplasmic space [GO:0042597]; cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2gbaa__d2jl0a2__1			Proteobacteria		periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	
d2gbcb2_d1x2ea___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	aminopeptidase activity [GO:0004177]
d2gbja__d2mi8a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2gbld1_d2gble1__1			Cyanobacteria	Cyanobacteria	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]
d2gbmc__d5ferf___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosolic small ribosomal subunit [GO:0022627]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]; translation [GO:0006412]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]; translation [GO:0006412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosolic small ribosomal subunit [GO:0022627]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d2gbta__d2wn0a___1	Metazoa		Chordata		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]		chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	
d2gbvf__d1n19a___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d2gbvf__d1xtlb___1	Metazoa		Chordata	Firmicutes	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; removal of superoxide radicals [GO:0019430]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	removal of superoxide radicals [GO:0019430]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	plasma membrane [GO:0005886]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d2gbvi__d4b3ee___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d2gbwa1_d2a06e2__1		Metazoa	Proteobacteria	Chordata	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cellular aromatic compound metabolic process [GO:0006725]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	dioxygenase activity [GO:0051213]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d2gbwb__d4xbyh___1			Proteobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]	limonene-1,2-epoxide hydrolase activity [GO:0018744]	cellular aromatic compound metabolic process [GO:0006725]				dioxygenase activity [GO:0051213]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d2gbwc1_d2fyue2__1		Metazoa	Proteobacteria	Chordata	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cellular aromatic compound metabolic process [GO:0006725]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	dioxygenase activity [GO:0051213]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d2gbxa1_d1ndoa1__1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	cellular aromatic compound metabolic process [GO:0006725]	aromatic compound catabolic process [GO:0019439]			dioxygenase activity [GO:0051213]	dioxygenase activity [GO:0051213]
d2gbxc2_d5aewu2__1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	cellular aromatic compound metabolic process [GO:0006725]	aromatic compound catabolic process [GO:0019439]			dioxygenase activity [GO:0051213]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2gbxd__d2cc3b___1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type IV secretion system complex [GO:0043684]; identical protein binding [GO:0042802]; protein secretion by the type IV secretion system [GO:0030255]	cellular aromatic compound metabolic process [GO:0006725]	protein secretion by the type IV secretion system [GO:0030255]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type IV secretion system complex [GO:0043684]	dioxygenase activity [GO:0051213]	identical protein binding [GO:0042802]
d2gbxe1_d2hmoa1__1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	cellular aromatic compound metabolic process [GO:0006725]	aromatic compound catabolic process [GO:0019439]			dioxygenase activity [GO:0051213]	dioxygenase activity [GO:0051213]
d2gbxf__d1o7nb___1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	cellular aromatic compound metabolic process [GO:0006725]	aromatic compound catabolic process [GO:0019439]			dioxygenase activity [GO:0051213]	dioxygenase activity [GO:0051213]
d2gc0a2_d2paeb___1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	isomerase activity [GO:0016853]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]	isomerase activity [GO:0016853]
d2gc4a__d1mg3a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2gc4c__d1cyxa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cytochrome o ubiquinol oxidase complex [GO:0009319]; integral component of external side of plasma membrane [GO:0071575]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome bo3 ubiquinol oxidase activity [GO:0009486]; cytochrome o ubiquinol oxidase activity [GO:0008827]; cytochrome-c oxidase activity [GO:0004129]; electron transfer activity [GO:0009055]; oxidoreduction-driven active transmembrane transporter activity [GO:0015453]; proton transmembrane transporter activity [GO:0015078]; ubiquinone binding [GO:0048039]; aerobic electron transport chain [GO:0019646]; aerobic respiration [GO:0009060]; ATP synthesis coupled electron transport [GO:0042773]; electron transport coupled proton transport [GO:0015990]		aerobic electron transport chain [GO:0019646]; aerobic respiration [GO:0009060]; ATP synthesis coupled electron transport [GO:0042773]; electron transport coupled proton transport [GO:0015990]	periplasmic space [GO:0042597]	cytochrome o ubiquinol oxidase complex [GO:0009319]; integral component of external side of plasma membrane [GO:0071575]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; cytochrome bo3 ubiquinol oxidase activity [GO:0009486]; cytochrome-c oxidase activity [GO:0004129]; cytochrome o ubiquinol oxidase activity [GO:0008827]; electron transfer activity [GO:0009055]; oxidoreduction-driven active transmembrane transporter activity [GO:0015453]; proton transmembrane transporter activity [GO:0015078]; ubiquinone binding [GO:0048039]
d2gc4g__d3t6zc2__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]			periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2gc4k__d2iweg___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2gc4k__d2vw7b1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2gc4l__d3cyto___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]	mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2gc4m__d1jjub___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2gc7c__d1asoa3__1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]			periplasmic space [GO:0042597]	extracellular region [GO:0005576]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]
d2gc7d__d3zoxd___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2gc7h__d1h31c1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2gc7k__d3nsya1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d2gc7p__d1m70b2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2gcqa__d1fp6b___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; 'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	molybdenum-iron nitrogenase complex [GO:0016612]	adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2gcqa__d5wdrb___1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; 'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	membrane [GO:0016020]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; signal transduction [GO:0007165]	'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	membrane [GO:0016020]	adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d2gcya1_d4c4kt___1		Metazoa		Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d2gcya1_d4kkcd2__1				Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d2gcya2_d3nn8f___1												
d2gd1o2_d3pwka2__1			Firmicutes		cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	
d2gd4b1_d5q0ea___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d2gd4h1_d1s6fa___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2gddb__d4q7za___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	azurophil granule lumen [GO:0035578]; extracellular space [GO:0005615]; heparin binding [GO:0008201]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular space [GO:0005615]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	heparin binding [GO:0008201]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2gddb__d4yt7h___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	proteolysis [GO:0006508]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d2gdfb__d2a3xc___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d2gdfd__d3b9cc___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; intracellular [GO:0005622]; carbohydrate binding [GO:0030246]				cytoplasm [GO:0005737]; intracellular [GO:0005622]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d2gdma__d2g11a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2gdma__d5fvbd___1	Viridiplantae		Streptophyta	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2gdqa1_d2muca1__1			Firmicutes	Proteobacteria	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; beta-ketoadipate pathway [GO:0042952]; cellular amino acid catabolic process [GO:0009063]		beta-ketoadipate pathway [GO:0042952]; cellular amino acid catabolic process [GO:0009063]			isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d2gdqa2_d3ucda1__1		Metazoa	Firmicutes	Chordata	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2gdqb1_d5fjpd2__1			Firmicutes	Actinobacteria	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]		menaquinone biosynthetic process [GO:0009234]			isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d2gdra1_d1yexb___1			Proteobacteria	Proteobacteria	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]		cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cytosol [GO:0005829]	glutathione transferase activity [GO:0004364]	thioredoxin peroxidase activity [GO:0008379]
d2gdrb1_d1q4ja2__1			Proteobacteria	Apicomplexa	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]					glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2gdre1_d1syxc___1		Metazoa	Proteobacteria	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]		cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]		cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	glutathione transferase activity [GO:0004364]	
d2gdrf1_d2f51a1__1			Proteobacteria		glutathione transferase activity [GO:0004364]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]	glutathione transferase activity [GO:0004364]	protein disulfide oxidoreductase activity [GO:0015035]
d2gdrf2_d4zbad2__1		Fungi	Proteobacteria	Basidiomycota	glutathione transferase activity [GO:0004364]						glutathione transferase activity [GO:0004364]	
d2gdsa1_d3js4d1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2gdsa2_d4gunk2__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2gdsb2_d4l2db2__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2gdsc1_d4l2db1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2gdsd1_d1ap6b1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2gdsd2_d6elka2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	removal of superoxide radicals [GO:0019430]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]
d2gdva2_d4howa1__1			Actinobacteria	Proteobacteria	sucrose phosphorylase activity [GO:0009018]; cellular carbohydrate metabolic process [GO:0044262]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cellular carbohydrate metabolic process [GO:0044262]	carbohydrate metabolic process [GO:0005975]			sucrose phosphorylase activity [GO:0009018]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d2gdwa2_d1l0ha___1			Firmicutes	Proteobacteria	hydrolase activity, acting on ester bonds [GO:0016788]; ligase activity [GO:0016874]; phosphopantetheine binding [GO:0031177]; antibiotic biosynthetic process [GO:0017000]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	antibiotic biosynthetic process [GO:0017000]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	hydrolase activity, acting on ester bonds [GO:0016788]; ligase activity [GO:0016874]; phosphopantetheine binding [GO:0031177]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]
d2gdza1_d4wlfd1__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; 15-hydroxyprostaglandin dehydrogenase (NAD+) activity [GO:0016404]; catalytic activity [GO:0003824]; NAD binding [GO:0051287]; NAD+ binding [GO:0070403]; prostaglandin E receptor activity [GO:0004957]; protein homodimerization activity [GO:0042803]; ductus arteriosus closure [GO:0097070]; female pregnancy [GO:0007565]; kidney development [GO:0001822]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; negative regulation of cell cycle [GO:0045786]; ovulation [GO:0030728]; parturition [GO:0007567]; positive regulation of apoptotic process [GO:0043065]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; prostaglandin metabolic process [GO:0006693]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; thrombin-activated receptor signaling pathway [GO:0070493]; transforming growth factor beta receptor signaling pathway [GO:0007179]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	ductus arteriosus closure [GO:0097070]; female pregnancy [GO:0007565]; kidney development [GO:0001822]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; negative regulation of cell cycle [GO:0045786]; ovulation [GO:0030728]; parturition [GO:0007567]; positive regulation of apoptotic process [GO:0043065]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; prostaglandin metabolic process [GO:0006693]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; thrombin-activated receptor signaling pathway [GO:0070493]; transforming growth factor beta receptor signaling pathway [GO:0007179]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	basolateral plasma membrane [GO:0016323]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	15-hydroxyprostaglandin dehydrogenase (NAD+) activity [GO:0016404]; catalytic activity [GO:0003824]; NAD+ binding [GO:0070403]; NAD binding [GO:0051287]; prostaglandin E receptor activity [GO:0004957]; protein homodimerization activity [GO:0042803]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d2ge5b__d5desa1__1			Proteobacteria	Negarnaviricota	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cap snatching [GO:0075526]; suppression by virus of host RNA polymerase II activity [GO:0039523]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	DNA restriction-modification system [GO:0009307]	cap snatching [GO:0075526]; suppression by virus of host RNA polymerase II activity [GO:0039523]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]		host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2gecb__d2geca1__1					host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]			host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; viral nucleocapsid [GO:0019013]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; viral nucleocapsid [GO:0019013]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d2gela1_d3u8xc2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2gela2_d3fe1a1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	blood microparticle [GO:0072562]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; neutrophil degranulation [GO:0043312]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; neutrophil degranulation [GO:0043312]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d2gelg2_d3sk3b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]		acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]
d2gelg2_d4h0vb2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2gepa1_d3mmad1__1			Proteobacteria	Euryarchaeota	sulfite reductase complex (NADPH) [GO:0009337]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	sulfur compound metabolic process [GO:0006790]	sulfite reductase complex (NADPH) [GO:0009337]	membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d2gepa2_d1zj9a2__1			Proteobacteria	Actinobacteria	sulfite reductase complex (NADPH) [GO:0009337]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	cell wall [GO:0005618]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]	sulfite reductase complex (NADPH) [GO:0009337]	cell wall [GO:0005618]; cytosol [GO:0005829]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]
d2gepa2_d3mm8b1__1			Proteobacteria	Euryarchaeota	sulfite reductase complex (NADPH) [GO:0009337]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	sulfur compound metabolic process [GO:0006790]	sulfite reductase complex (NADPH) [GO:0009337]	membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d2gerd1_d3ausa1__1	Metazoa		Chordata	Firmicutes	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; identical protein binding [GO:0042802]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; identical protein binding [GO:0042802]
d2gerd1_d5o30b___1	Metazoa		Chordata	Actinobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]		cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]	
d2gewa2_d2xfna2__1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cholesterol metabolic process [GO:0008203]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	extracellular region [GO:0005576]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d2geyb__d1sjwa___1			Actinobacteria	Actinobacteria	polyketide metabolic process [GO:0030638]	polyketide metabolic process [GO:0030638]	polyketide metabolic process [GO:0030638]	polyketide metabolic process [GO:0030638]				
d2geyd__d2f98d___1			Actinobacteria	Actinobacteria	polyketide metabolic process [GO:0030638]	intramolecular lyase activity [GO:0016872]; antibiotic biosynthetic process [GO:0017000]; daunorubicin biosynthetic process [GO:1901771]; doxorubicin metabolic process [GO:0044598]	polyketide metabolic process [GO:0030638]	antibiotic biosynthetic process [GO:0017000]; daunorubicin biosynthetic process [GO:1901771]; doxorubicin metabolic process [GO:0044598]				intramolecular lyase activity [GO:0016872]
d2gf0a1_d4v0lb1__1	Metazoa	Viridiplantae	Chordata	Chlorophyta	plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; signal transduction [GO:0007165]	axoneme [GO:0005930]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; cilium assembly [GO:0060271]; intracellular protein transport [GO:0006886]; protein localization to cilium [GO:0061512]; vesicle-mediated transport [GO:0016192]	signal transduction [GO:0007165]	cilium assembly [GO:0060271]; intracellular protein transport [GO:0006886]; protein localization to cilium [GO:0061512]; vesicle-mediated transport [GO:0016192]	plasma membrane [GO:0005886]	axoneme [GO:0005930]; cytoplasm [GO:0005737]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GTP binding [GO:0005525]
d2gf2a1_d2aefb1__1	Metazoa		Chordata	Euryarchaeota	mitochondrial matrix [GO:0005759]; 3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574]	potassium ion transport [GO:0006813]	mitochondrial matrix [GO:0005759]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2gf2c1_d3hada2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; 3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	mitochondrial matrix [GO:0005759]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d2gf2d1_d3etde2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; 3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	mitochondrial matrix [GO:0005759]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d2gf3b2_d1daof2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	tetrahydrofolate metabolic process [GO:0046653]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	sarcosine oxidase activity [GO:0008115]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d2gfba1_d1ddhb___1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2gfba2_d5vsil2__1												
d2gfbc1_d2w9lp___1		Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2gfbc2_d3haeq1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]		
d2gfbd1_d5b4ml1__1												
d2gfbd2_d3sgjc2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		IgG binding [GO:0019864]
d2gfbe2_d1jhtb2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2gfbf1_d4ocyl1__1		Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d2gfbf2_d1zs8j___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2gfbf2_d5cjba1__1		Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; collagen receptor activity [GO:0038064]; neutrophil degranulation [GO:0043312]; osteoclast differentiation [GO:0030316]; regulation of immune response [GO:0050776]		neutrophil degranulation [GO:0043312]; osteoclast differentiation [GO:0030316]; regulation of immune response [GO:0050776]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		collagen receptor activity [GO:0038064]
d2gfbh2_d5wjoa1__1												
d2gfbi2_d4xhjc1__1						host cell Golgi apparatus [GO:0044177]; host cell plasma membrane [GO:0020002]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; fusion of virus membrane with host plasma membrane [GO:0019064]		fusion of virus membrane with host plasma membrane [GO:0019064]		host cell Golgi apparatus [GO:0044177]; host cell plasma membrane [GO:0020002]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		
d2gfbj1_d2pyfb1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2gfbj2_d3ietc1__1		Metazoa		Chordata		apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; integral component of membrane [GO:0016021]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge of lamellipodium [GO:0061851]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; tetraspanin-enriched microdomain [GO:0097197]; chaperone binding [GO:0051087]; chemokine binding [GO:0019956]; signaling receptor binding [GO:0005102]; actin-mediated cell contraction [GO:0070252]; amino acid transmembrane transport [GO:0003333]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; folic acid transport [GO:0015884]; invadopodium organization [GO:1905863]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lymph node development [GO:0048535]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell fate commitment [GO:0060838]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular component movement [GO:0051272]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of platelet activation [GO:0010572]; positive regulation of platelet aggregation [GO:1901731]; prostaglandin metabolic process [GO:0006693]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of myofibroblast contraction [GO:1904328]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; tube morphogenesis [GO:0035239]; visceral serous pericardium development [GO:0061032]; water transport [GO:0006833]; wound healing, spreading of cells [GO:0044319]		actin-mediated cell contraction [GO:0070252]; amino acid transmembrane transport [GO:0003333]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; folic acid transport [GO:0015884]; invadopodium organization [GO:1905863]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell fate commitment [GO:0060838]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular component movement [GO:0051272]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of platelet activation [GO:0010572]; positive regulation of platelet aggregation [GO:1901731]; prostaglandin metabolic process [GO:0006693]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of myofibroblast contraction [GO:1904328]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; tube morphogenesis [GO:0035239]; visceral serous pericardium development [GO:0061032]; water transport [GO:0006833]; wound healing, spreading of cells [GO:0044319]		apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; integral component of membrane [GO:0016021]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge of lamellipodium [GO:0061851]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; tetraspanin-enriched microdomain [GO:0097197]		chaperone binding [GO:0051087]; chemokine binding [GO:0019956]; signaling receptor binding [GO:0005102]
d2gfbk1_d4l3cz___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2gfbk2_d3eyqc1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2gfbl1_d2d31e1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2gfbm2_d4am0b2__1						extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2gfbo1_d1zvoa2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2gfbp1_d1u8pb1__1												
d2gfbp1_d4rfel2__1												
d2gfbp2_d1pz5a1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2gfna1_d1sgma1__1			Actinobacteria	Firmicutes	DNA binding [GO:0003677]	DNA binding [GO:0003677]					DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2gfnb1_d1jtya1__1			Actinobacteria	Firmicutes	DNA binding [GO:0003677]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]		negative regulation of transcription, DNA-templated [GO:0045892]			DNA binding [GO:0003677]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2gfta__d1vrxa___1			Firmicutes	Actinobacteria	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	metabolic process [GO:0008152]	cellulose catabolic process [GO:0030245]			arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]
d2gfta__d4gxpb___1			Firmicutes	Thermotogae	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	metabolic process [GO:0008152]	cellulose catabolic process [GO:0030245]			arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d2gfxa1_d2d3tc2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation [GO:0006635]	cytosol [GO:0005829]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d2gg1a1_d1tgea1__1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; serine-type peptidase activity [GO:0008236]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; serine-type peptidase activity [GO:0008236]
d2ggea1_d4m6ua2__1			Firmicutes	Proteobacteria	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]		cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]			isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d2ggea2_d3tu2b1__1			Firmicutes		isomerase activity [GO:0016853]; metal ion binding [GO:0046872]						isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	
d2ggee1_d3uxld2__1			Firmicutes	Proteobacteria	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]		cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]			isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d2ggef2_d2p88a1__1			Firmicutes	Firmicutes	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]; peptide metabolic process [GO:0006518]		peptide metabolic process [GO:0006518]			isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]
d2ggka1_d2fkuc___1			Proteobacteria		N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]	
d2ggka1_d5h8le___1		Viridiplantae	Proteobacteria	Streptophyta	N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]; nitrogen compound metabolic process [GO:0006807]	N-carbamoylputrescine amidase activity [GO:0050126]; polyamine biosynthetic process [GO:0006596]	nitrogen compound metabolic process [GO:0006807]	polyamine biosynthetic process [GO:0006596]			N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]	N-carbamoylputrescine amidase activity [GO:0050126]
d2ggla1_d5h8ld___1		Viridiplantae	Proteobacteria	Streptophyta	N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]; nitrogen compound metabolic process [GO:0006807]	N-carbamoylputrescine amidase activity [GO:0050126]; polyamine biosynthetic process [GO:0006596]	nitrogen compound metabolic process [GO:0006807]	polyamine biosynthetic process [GO:0006596]			N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]	N-carbamoylputrescine amidase activity [GO:0050126]
d2gglc__d5h8jm___1		Viridiplantae	Proteobacteria	Streptophyta	N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]; nitrogen compound metabolic process [GO:0006807]	N-carbamoylputrescine amidase activity [GO:0050126]; polyamine biosynthetic process [GO:0006596]	nitrogen compound metabolic process [GO:0006807]	polyamine biosynthetic process [GO:0006596]			N-carbamoyl-D-amino acid hydrolase activity [GO:0047417]	N-carbamoylputrescine amidase activity [GO:0050126]
d2ggnx__d5sx3b1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]		heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2ggtb__d5jlyc___1	Metazoa	Metazoa	Chordata	Platyhelminthes	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; copper ion binding [GO:0005507]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]	cell [GO:0005623]	copper ion binding [GO:0005507]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2ggub1_d1bcph2__1	Metazoa		Chordata	Proteobacteria	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]		clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	toxin activity [GO:0090729]
d2gguc1_d1x2tb___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]		clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]
d2ggxa1_d3kmb11__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d2ggxc1_d1umrc___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]		clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	toxin activity [GO:0090729]
d2ggxc1_d4wcoc___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; regulation of immune response [GO:0050776]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cell surface receptor signaling pathway [GO:0007166]; regulation of immune response [GO:0050776]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]
d2gh5a2_d1vdca2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	chloroplast envelope [GO:0009941]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; thioredoxin-disulfide reductase activity [GO:0004791]; positive regulation of cell division [GO:0051781]; removal of superoxide radicals [GO:0019430]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	positive regulation of cell division [GO:0051781]; removal of superoxide radicals [GO:0019430]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	chloroplast envelope [GO:0009941]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]	thioredoxin-disulfide reductase activity [GO:0004791]
d2gh9a__d1xc1c___1			Deinococcus-Thermus	Proteobacteria	carbohydrate transmembrane transporter activity [GO:0015144]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]		ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]		periplasmic space [GO:0042597]	carbohydrate transmembrane transporter activity [GO:0015144]	metal ion binding [GO:0046872]
d2ghcx1_d4coxc1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	chloroplast [GO:0009507]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d2ghdx1_d2oyup1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d2ghhx2_d2ccab1__1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]
d2ghkx2_d2ccaa2__1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]
d2ghoa2_d1iw7a2__1			Deinococcus-Thermus	Deinococcus-Thermus	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]			DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d2ghob2_d2ja8c2__1		Fungi	Deinococcus-Thermus	Ascomycota	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	transcription, DNA-templated [GO:0006351]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]		cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]
d2ghpa2_d3bs9a___1	Fungi	Metazoa	Ascomycota	Chordata	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; negative regulation of cytokine biosynthetic process [GO:0042036]; negative regulation of translation [GO:0017148]; positive regulation of epithelial cell apoptotic process [GO:1904037]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of mRNA splicing, via spliceosome [GO:0048024]	spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; negative regulation of cytokine biosynthetic process [GO:0042036]; negative regulation of translation [GO:0017148]; positive regulation of epithelial cell apoptotic process [GO:1904037]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of mRNA splicing, via spliceosome [GO:0048024]	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904]	RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]	mRNA 3'-UTR AU-rich region binding [GO:0035925]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d2ghpb2_d1kooc2__1	Fungi	Metazoa	Ascomycota	Chordata	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d2ghpc2_d1opia___1	Fungi	Metazoa	Ascomycota	Chordata	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribosome [GO:0005840]; spliceosomal complex [GO:0005681]; identical protein binding [GO:0042802]; pre-mRNA branch point binding [GO:0045131]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270]; Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nuclear body organization [GO:0030575]; regulation of steroid biosynthetic process [GO:0050810]; spliceosomal complex assembly [GO:0000245]	spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nuclear body organization [GO:0030575]; regulation of steroid biosynthetic process [GO:0050810]; spliceosomal complex assembly [GO:0000245]	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]	nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribosome [GO:0005840]; spliceosomal complex [GO:0005681]	RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]	identical protein binding [GO:0042802]; pre-mRNA branch point binding [GO:0045131]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270]
d2ghpe2_d4ed5a1__1	Fungi	Metazoa	Ascomycota	Chordata	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]	RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]	AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d2ghpf2_d4cq1f2__1	Fungi	Metazoa	Ascomycota	Chordata	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]	RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d2ghpg2_d3b4md___1	Fungi	Metazoa	Ascomycota	Chordata	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	cytoplasm [GO:0005737]; nuclear inclusion body [GO:0042405]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; cellular response to lipopolysaccharide [GO:0071222]; MAPK cascade [GO:0000165]; modification by virus of host mRNA processing [GO:0046778]; mRNA 3'-end processing [GO:0031124]; mRNA splicing, via spliceosome [GO:0000398]; muscle contraction [GO:0006936]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of polynucleotide adenylyltransferase activity [GO:1904247]; RNA processing [GO:0006396]; termination of RNA polymerase II transcription [GO:0006369]	spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	cellular response to lipopolysaccharide [GO:0071222]; MAPK cascade [GO:0000165]; modification by virus of host mRNA processing [GO:0046778]; mRNA 3'-end processing [GO:0031124]; mRNA splicing, via spliceosome [GO:0000398]; muscle contraction [GO:0006936]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of polynucleotide adenylyltransferase activity [GO:1904247]; RNA processing [GO:0006396]; termination of RNA polymerase II transcription [GO:0006369]	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]	cytoplasm [GO:0005737]; nuclear inclusion body [GO:0042405]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]	RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]
d2ghqa__d1qh9a___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]	(S)-2-haloacid dehalogenase activity [GO:0018784]	negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]		extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]	(S)-2-haloacid dehalogenase activity [GO:0018784]
d2ghta__d5alta1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2ghtb__d1u7pb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; fructosamine metabolic process [GO:0030389]	negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]	fructosamine metabolic process [GO:0030389]	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]
d2ghwb1_d6b3sg1__1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2ghwb2_d3p0yl1__1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2ghwd2_d1ktrh1__1					host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]		endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]		host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]	
d2ghwd2_d3fonb1__1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ghza__d2jfcd1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ghzb__d2j57a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2gi0a__d2bw5a2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2gi7a1_d4uaob2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; tetraspanin-enriched microdomain [GO:0097197]; collagen binding [GO:0005518]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; blood coagulation [GO:0007596]; enzyme linked receptor protein signaling pathway [GO:0007167]; leukocyte migration [GO:0050900]; platelet activation [GO:0030168]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood coagulation [GO:0007596]; enzyme linked receptor protein signaling pathway [GO:0007167]; leukocyte migration [GO:0050900]; platelet activation [GO:0030168]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; tetraspanin-enriched microdomain [GO:0097197]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	collagen binding [GO:0005518]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2gi7a1_d5kvfl1__1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; tetraspanin-enriched microdomain [GO:0097197]; collagen binding [GO:0005518]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; blood coagulation [GO:0007596]; enzyme linked receptor protein signaling pathway [GO:0007167]; leukocyte migration [GO:0050900]; platelet activation [GO:0030168]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; enzyme linked receptor protein signaling pathway [GO:0007167]; leukocyte migration [GO:0050900]; platelet activation [GO:0030168]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; tetraspanin-enriched microdomain [GO:0097197]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	collagen binding [GO:0005518]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2gi7b1_d3oj2d2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; tetraspanin-enriched microdomain [GO:0097197]; collagen binding [GO:0005518]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; blood coagulation [GO:0007596]; enzyme linked receptor protein signaling pathway [GO:0007167]; leukocyte migration [GO:0050900]; platelet activation [GO:0030168]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	blood coagulation [GO:0007596]; enzyme linked receptor protein signaling pathway [GO:0007167]; leukocyte migration [GO:0050900]; platelet activation [GO:0030168]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; tetraspanin-enriched microdomain [GO:0097197]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	collagen binding [GO:0005518]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2giad__d3n1ja___1		Viridiplantae		Streptophyta	kinetoplast [GO:0020023]; mitochondrion [GO:0005739]; DNA binding [GO:0003677]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; regulation of transcription, DNA-templated [GO:0006355]; RNA modification [GO:0009451]	mitochondrion [GO:0005739]; DNA binding [GO:0003677]; single-stranded DNA binding [GO:0003697]; defense response [GO:0006952]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]; RNA modification [GO:0009451]	defense response [GO:0006952]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]	kinetoplast [GO:0020023]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	DNA binding [GO:0003677]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; single-stranded DNA binding [GO:0003697]
d2giea__d1rvab___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; type II site-specific deoxyribonuclease activity [GO:0009036]
d2gild__d4d0lb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin V binding [GO:0031489]; protein domain specific binding [GO:0019904]; antigen processing and presentation [GO:0019882]; early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; minus-end-directed organelle transport along microtubule [GO:0072385]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine methylation [GO:0018125]; protein localization to Golgi apparatus [GO:0034067]; Rab protein signal transduction [GO:0032482]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; viral process [GO:0016032]	axon [GO:0030424]; cell [GO:0005623]; centriolar satellite [GO:0034451]; cleavage furrow [GO:0032154]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; multivesicular body [GO:0005771]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; postsynaptic recycling endosome [GO:0098837]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; Schaffer collateral - CA1 synapse [GO:0098685]; spindle pole [GO:0000922]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133]; vesicle [GO:0031982]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; microtubule binding [GO:0008017]; myosin V binding [GO:0031489]; syntaxin binding [GO:0019905]; amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; plasma membrane to endosome transport [GO:0048227]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-translational protein modification [GO:0043687]; protein localization to plasma membrane [GO:0072659]; Rab protein signal transduction [GO:0032482]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; renal water homeostasis [GO:0003091]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003]	antigen processing and presentation [GO:0019882]; early endosome to Golgi transport [GO:0034498]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; minus-end-directed organelle transport along microtubule [GO:0072385]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine methylation [GO:0018125]; protein localization to Golgi apparatus [GO:0034067]; Rab protein signal transduction [GO:0032482]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; viral process [GO:0016032]	amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; plasma membrane to endosome transport [GO:0048227]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-translational protein modification [GO:0043687]; protein localization to plasma membrane [GO:0072659]; Rab protein signal transduction [GO:0032482]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; renal water homeostasis [GO:0003091]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]	axon [GO:0030424]; cell [GO:0005623]; centriolar satellite [GO:0034451]; cleavage furrow [GO:0032154]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; multivesicular body [GO:0005771]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; postsynaptic recycling endosome [GO:0098837]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; Schaffer collateral - CA1 synapse [GO:0098685]; spindle pole [GO:0000922]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133]; vesicle [GO:0031982]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin V binding [GO:0031489]; protein domain specific binding [GO:0019904]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; microtubule binding [GO:0008017]; myosin V binding [GO:0031489]; syntaxin binding [GO:0019905]
d2gima__d4g72b2__1			Cyanobacteria	Deinococcus-Thermus	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]			thylakoid membrane [GO:0042651]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2gimc__d2fqga2__1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	thylakoid membrane [GO:0042651]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d2ginb__d4h6bf___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; stromule [GO:0010319]; allene-oxide cyclase activity [GO:0046423]; jasmonic acid biosynthetic process [GO:0009695]; response to cold [GO:0009409]	allene-oxide cyclase activity [GO:0046423]; jasmonic acid biosynthetic process [GO:0009695]	jasmonic acid biosynthetic process [GO:0009695]; response to cold [GO:0009409]	jasmonic acid biosynthetic process [GO:0009695]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; stromule [GO:0010319]		allene-oxide cyclase activity [GO:0046423]	allene-oxide cyclase activity [GO:0046423]
d2gita1_d4nx3a3__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2gita2_d4y2da1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2gitd2_d3w39d1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2gitd2_d5ksab1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2gite2_d2qqkl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2giwa__d3zowh___1	Metazoa		Chordata	Proteobacteria	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]		cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2gixd1_d1ds6b___1	Metazoa	Metazoa	Chordata	Chordata	dendrite [GO:0030425]; dendritic spine [GO:0043197]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; intrinsic component of membrane [GO:0031224]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cellular response to mechanical stimulus [GO:0071260]; magnesium ion transport [GO:0015693]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of skeletal muscle contraction via regulation of action potential [GO:0014861]; relaxation of cardiac muscle [GO:0055119]; relaxation of skeletal muscle [GO:0090076]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; cellular response to redox state [GO:0071461]; multicellular organism development [GO:0007275]; negative regulation of cell adhesion [GO:0007162]; negative regulation of trophoblast cell migration [GO:1901164]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cellular response to mechanical stimulus [GO:0071260]; magnesium ion transport [GO:0015693]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of skeletal muscle contraction via regulation of action potential [GO:0014861]; relaxation of cardiac muscle [GO:0055119]; relaxation of skeletal muscle [GO:0090076]	cellular response to redox state [GO:0071461]; multicellular organism development [GO:0007275]; negative regulation of cell adhesion [GO:0007162]; negative regulation of trophoblast cell migration [GO:1901164]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	dendrite [GO:0030425]; dendritic spine [GO:0043197]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; intrinsic component of membrane [GO:0031224]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; voltage-gated potassium channel complex [GO:0008076]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]
d2giza1_d2epfd1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d2gizb1_d2epfc1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d2gj3a__d5svub___1		Viridiplantae	Proteobacteria	Streptophyta	ATP binding [GO:0005524]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; photoreceptor activity [GO:0009881]; circadian rhythm [GO:0007623]; flower development [GO:0009908]; protein ubiquitination [GO:0016567]; protein-chromophore linkage [GO:0018298]; response to blue light [GO:0009637]	nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	circadian rhythm [GO:0007623]; flower development [GO:0009908]; protein-chromophore linkage [GO:0018298]; protein ubiquitination [GO:0016567]; response to blue light [GO:0009637]		cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	ATP binding [GO:0005524]; protein histidine kinase activity [GO:0004673]	photoreceptor activity [GO:0009881]
d2gj5a__d2rcqa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]		epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d2gj6a1_d3dvga2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2gj6e2_d5jxec1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2gj7a1_d3sdxg1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2gj7a2_d4uv4l1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2gj9a__d6bc1b1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; chaperone-mediated protein folding [GO:0061077]; response to pH [GO:0009268]; tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; histone deacetylase binding [GO:0042826]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cell-matrix adhesion [GO:0007160]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	chaperone-mediated protein folding [GO:0061077]; response to pH [GO:0009268]; tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]	ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; histone deacetylase binding [GO:0042826]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]
d2gjdd__d3p9ha1__1	Fungi	Metazoa	Ascomycota	Chordata	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; ATP binding [GO:0005524]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; cell division [GO:0051301]; mitotic spindle elongation [GO:0000022]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]; autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	cell division [GO:0051301]; mitotic spindle elongation [GO:0000022]; protein sumoylation [GO:0016925]	autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]	calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]
d2gjja2_d1dlhe1__1		Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d2gjja2_d4nx3a4__1												
d2gjjb1_d1r3ka1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2gjpa1_d1r47b1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]; starch catabolic process [GO:0005983]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	starch catabolic process [GO:0005983]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d2gjra1_d1wpca1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]; starch catabolic process [GO:0005983]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]; starch catabolic process [GO:0005983]	starch catabolic process [GO:0005983]	starch catabolic process [GO:0005983]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]	calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]
d2gjra2_d2gk1.a__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]; starch catabolic process [GO:0005983]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	starch catabolic process [GO:0005983]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d2gjta1_d2b4pb___1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; axon [GO:0030424]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; Wnt-protein binding [GO:0017147]; axon guidance [GO:0007411]; cell morphogenesis [GO:0000902]; glomerular visceral epithelial cell differentiation [GO:0072112]; glomerulus development [GO:0032835]; lamellipodium assembly [GO:0030032]; monocyte chemotaxis [GO:0002548]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of glomerular filtration [GO:0003105]; negative regulation of neuron projection development [GO:0010977]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of glomerular filtration [GO:0003093]; regulation of synapse organization [GO:0050807]; slit diaphragm assembly [GO:0036060]	protein tyrosine phosphatase activity [GO:0004725]	axon guidance [GO:0007411]; cell morphogenesis [GO:0000902]; glomerular visceral epithelial cell differentiation [GO:0072112]; glomerulus development [GO:0032835]; lamellipodium assembly [GO:0030032]; monocyte chemotaxis [GO:0002548]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of glomerular filtration [GO:0003105]; negative regulation of neuron projection development [GO:0010977]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of glomerular filtration [GO:0003093]; regulation of synapse organization [GO:0050807]; slit diaphragm assembly [GO:0036060]		apical plasma membrane [GO:0016324]; axon [GO:0030424]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]		cadherin binding [GO:0045296]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; Wnt-protein binding [GO:0017147]	protein tyrosine phosphatase activity [GO:0004725]
d2gjua__d2a22b2__1			Euryarchaeota	Apicomplexa		cytosol [GO:0005829]; retromer complex [GO:0030904]; retrograde transport, endosome to Golgi [GO:0042147]		retrograde transport, endosome to Golgi [GO:0042147]		cytosol [GO:0005829]; retromer complex [GO:0030904]		
d2gjub__d1nnwa___1			Euryarchaeota	Euryarchaeota								
d2gjuc__d1nnwb___1			Euryarchaeota	Euryarchaeota								
d2gjuc__d1s8eb___1			Euryarchaeota	Euryarchaeota		3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]; double-strand break repair [GO:0006302]		double-strand break repair [GO:0006302]				3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]
d2gjud__d4wwla1__1			Euryarchaeota	Proteobacteria		outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]		nucleotide catabolic process [GO:0009166]		outer membrane-bounded periplasmic space [GO:0030288]		5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]
d2gjxd1_d4im4f___1	Metazoa		Chordata	Firmicutes	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]; acetylxylan esterase activity [GO:0046555]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; glucomannan catabolic process [GO:2000884]; xylan catabolic process [GO:0045493]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	cellulose catabolic process [GO:0030245]; glucomannan catabolic process [GO:2000884]; xylan catabolic process [GO:0045493]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	extracellular region [GO:0005576]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	acetylxylan esterase activity [GO:0046555]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d2gjxh1_d1hp4a1__1	Metazoa		Chordata	Actinobacteria	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	carbohydrate metabolic process [GO:0005975]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]		acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	beta-N-acetylhexosaminidase activity [GO:0004563]
d2gjya1_d1k5dh___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]		androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	adherens junction [GO:0005912]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	actin binding [GO:0003779]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2gjza2_d4kmlb1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]	metal ion binding [GO:0046872]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d2gk0a1_d1g7mb___1	Metazoa	Metazoa	Chordata	Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2gk1.1_d1mqpa2__1	Metazoa		Chordata	Firmicutes	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	glucuronoxylan catabolic process [GO:2000886]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	extracellular region [GO:0005576]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]
d2gk1.1_d1qbaa4__1	Metazoa		Chordata	Proteobacteria	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	periplasmic space [GO:0042597]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]
d2gk1.4_d1gqia2__1	Metazoa		Chordata	Proteobacteria	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	glucuronoxylan catabolic process [GO:2000886]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]
d2gk1.5_d2xpka1__1	Metazoa		Chordata	Firmicutes	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]		acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d2gk1.6_d2cbjb3__1	Metazoa		Chordata	Firmicutes	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]		acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d2gk1.a_d2gjxa1__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d2gk1i1_d1jgia2__1	Metazoa		Chordata	Proteobacteria	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	carbohydrate metabolic process [GO:0005975]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	extracellular region [GO:0005576]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	amylosucrase activity [GO:0047669]
d2gk1k1_d3t0ba3__1	Metazoa		Chordata	Proteobacteria	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	lactose catabolic process [GO:0005990]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	beta-galactosidase complex [GO:0009341]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2gkda__d4c94a1__1		Viridiplantae	Actinobacteria	Streptophyta		abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]		abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]				abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2gkea2_d3ejxd2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]	diaminopimelate epimerase activity [GO:0008837]	diaminopimelate epimerase activity [GO:0008837]
d2gkia2_d5f7el2__1	Metazoa		Chordata									
d2gkib1_d3pxja1__1	Metazoa	Metazoa	Chordata	Arthropoda		axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]		axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]		axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]		heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d2gkja1_d3g7ka1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	methylitaconate delta-isomerase activity [GO:0050100]; cofactor catabolic process [GO:0051187]	lysine biosynthetic process via diaminopimelate [GO:0009089]	cofactor catabolic process [GO:0051187]	cytosol [GO:0005829]		diaminopimelate epimerase activity [GO:0008837]	methylitaconate delta-isomerase activity [GO:0050100]
d2gkja2_d1t6ka1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	lysine biosynthetic process via diaminopimelate [GO:0009089]	pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	cytosol [GO:0005829]		diaminopimelate epimerase activity [GO:0008837]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]
d2gkla__d4gyqc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2gkmb__d6bmeb___1		Viridiplantae	Actinobacteria	Chlorophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; oxygen binding [GO:0019825]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; oxygen binding [GO:0019825]; thioredoxin peroxidase activity [GO:0008379]
d2gknb__d1s61b___1			Actinobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d2gkve__d1qrwa___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	serine-type endopeptidase inhibitor activity [GO:0004867]	serine-type endopeptidase activity [GO:0004252]
d2gl3b__d1s56b___1			Actinobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d2gl5a2_d2ggec2__1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d2gl5b1_d3b97b2__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]		cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d2gl5b2_d2al1a2__1		Fungi	Proteobacteria	Ascomycota	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2glka__d5nh8b___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d2gllf__d5byuh___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	
d2glmd__d4fq9h___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	unsaturated fatty acid biosynthetic process [GO:0006636]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]
d2glme__d3r3ba___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]
d2glna__d3dhtb___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin beta binding [GO:0031722]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; glutathione metabolic process [GO:0006749]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; protein heterooligomerization [GO:0051291]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cellular oxidant detoxification [GO:0098869]; glutathione metabolic process [GO:0006749]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; protein heterooligomerization [GO:0051291]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin beta binding [GO:0031722]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2glnb__d5fvbb___1			Actinobacteria	Cyanobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	
d2glpf__d4b0ce___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	unsaturated fatty acid biosynthetic process [GO:0006636]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]
d2glra2_d1mdka___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d2glrb1_d1a0fa1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; response to hydrogen peroxide [GO:0042542]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	cytoplasm [GO:0005737]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d2glrb2_d2imkb1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	cytoplasm [GO:0005737]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d2glsa1_d3qajl1__1			Proteobacteria		cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	
d2glsa2_d1htoe2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d2glsa2_d4lnfh2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d2glsb1_d2whid1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d2glsb2_d4lnfd2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d2glsc2_d1f52h2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d2glsc2_d4lnfe2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d2glsd2_d1qh4d2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]
d2glse1_d4lnkc1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d2glsf1_d1fpyl1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d2glsi1_d1fpyf1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d2glsi1_d4lnik1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d2glsj1_d4lnkb1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d2glsj2_d1htos2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d2glsk1_d3ng0a1__1			Proteobacteria	Cyanobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d2glsk2_d3l2fg2__1			Proteobacteria		cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	
d2glsl1_d4lnih1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]; membrane [GO:0016020]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d2glsl2_d3l2gd2__1			Proteobacteria		cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]	
d2glta1_d2c00b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; glutathione synthase activity [GO:0004363]; magnesium ion binding [GO:0000287]; glutathione biosynthetic process [GO:0006750]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	glutathione biosynthetic process [GO:0006750]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; glutathione synthase activity [GO:0004363]; magnesium ion binding [GO:0000287]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2glve__d4iena___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	thiolester hydrolase activity [GO:0016790]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	thiolester hydrolase activity [GO:0016790]
d2glvf__d1wlvg___1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	thiolester hydrolase activity [GO:0016790]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	thiolester hydrolase activity [GO:0016790]
d2glvi__d3azbf___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	hydro-lyase activity [GO:0016836]
d2gm8d2_d1irmc___1		Metazoa	Crenarchaeota	Chordata	cytosol [GO:0005829]; thiaminase activity [GO:0050334]; thiamine metabolic process [GO:0006772]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	thiamine metabolic process [GO:0006772]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	cytosol [GO:0005829]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	thiaminase activity [GO:0050334]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d2gmfa1_d3ncfa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]	hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]
d2gmja2_d1f8ra2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of mitochondrial inner membrane [GO:0031305]; membrane [GO:0016020]; mitochondrion [GO:0005739]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; electron-transferring-flavoprotein dehydrogenase activity [GO:0004174]; flavin adenine dinucleotide binding [GO:0050660]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, oxidizing metal ions with flavin as acceptor [GO:0043783]; ubiquinone binding [GO:0048039]; electron transport chain [GO:0022900]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	electron transport chain [GO:0022900]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	integral component of mitochondrial inner membrane [GO:0031305]; membrane [GO:0016020]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; electron-transferring-flavoprotein dehydrogenase activity [GO:0004174]; flavin adenine dinucleotide binding [GO:0050660]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, oxidizing metal ions with flavin as acceptor [GO:0043783]; ubiquinone binding [GO:0048039]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]
d2gmjb2_d1naaa2__1	Metazoa	Fungi	Chordata	Basidiomycota	integral component of mitochondrial inner membrane [GO:0031305]; membrane [GO:0016020]; mitochondrion [GO:0005739]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; electron-transferring-flavoprotein dehydrogenase activity [GO:0004174]; flavin adenine dinucleotide binding [GO:0050660]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, oxidizing metal ions with flavin as acceptor [GO:0043783]; ubiquinone binding [GO:0048039]; electron transport chain [GO:0022900]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	electron transport chain [GO:0022900]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]	cellulose catabolic process [GO:0030245]	integral component of mitochondrial inner membrane [GO:0031305]; membrane [GO:0016020]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; electron-transferring-flavoprotein dehydrogenase activity [GO:0004174]; flavin adenine dinucleotide binding [GO:0050660]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, oxidizing metal ions with flavin as acceptor [GO:0043783]; ubiquinone binding [GO:0048039]	cellobiose dehydrogenase (acceptor) activity [GO:0047735]; flavin adenine dinucleotide binding [GO:0050660]; metal ion binding [GO:0046872]
d2gmna1_d2yz3b___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; metal ion binding [GO:0046872]
d2gmrh2_d1rvjh1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	integral component of membrane [GO:0016021]; plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	integral component of membrane [GO:0016021]; plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	integral component of membrane [GO:0016021]; plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]	bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]
d2gmta__d2j92a1__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2gmwb__d4hgna___1			Proteobacteria	Bacteroidetes	cytosol [GO:0005829]; D,D-heptose 1,7-bisphosphate phosphatase activity [GO:0034200]; magnesium ion binding [GO:0000287]; zinc ion binding [GO:0008270]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]		D,D-heptose 1,7-bisphosphate phosphatase activity [GO:0034200]; magnesium ion binding [GO:0000287]; zinc ion binding [GO:0008270]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d2gnda__d1h4gb___1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d2gndb__d3aktb___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d2gnta__d5o6na___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2gnvb__d2qrwc___1	Viridiplantae		Streptophyta	Actinobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d2go3a1_d3lpsa2__1			Aquificae	Proteobacteria	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	chromosome [GO:0005694]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; chromosome segregation [GO:0007059]; DNA topological change [GO:0006265]	lipid A biosynthetic process [GO:0009245]	chromosome segregation [GO:0007059]; DNA topological change [GO:0006265]		chromosome [GO:0005694]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]
d2go3a2_d3cwva2__1			Aquificae	Proteobacteria	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; DNA topological change [GO:0006265]	lipid A biosynthetic process [GO:0009245]	DNA topological change [GO:0006265]			metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]
d2goja2_d4f2nb2__1			Apicomplexa		cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2gojb1_d4yetb1__1			Apicomplexa	Apicomplexa	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2gojb2_d1wb8a2__1			Apicomplexa	Crenarchaeota	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2gova1_d3r8jb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; heme metabolic process [GO:0042168]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; negative regulation of mitochondrial membrane potential [GO:0010917]; neutrophil degranulation [GO:0043312]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940]	heme metabolic process [GO:0042168]	negative regulation of mitochondrial membrane potential [GO:0010917]; neutrophil degranulation [GO:0043312]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	heme binding [GO:0020037]	heme binding [GO:0020037]
d2goxa1_d1h3ac2__1	Metazoa		Chordata	Firmicutes	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	hopanoid biosynthetic process [GO:0019746]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d2gp3a__d5pnga___1	Metazoa	Metazoa	Chordata	Chordata	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d2gp3b__d3i3qb___1	Metazoa		Chordata	Proteobacteria	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]
d2gp3b__d5pnla___1	Metazoa	Metazoa	Chordata	Chordata	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d2gp5a__d5pmca___1	Metazoa	Metazoa	Chordata	Chordata	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d2gp6b2_d1u0mb2__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to hypoxia [GO:0001666]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; melanin biosynthetic process [GO:0042438]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to hypoxia [GO:0001666]	melanin biosynthetic process [GO:0042438]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2gp6b2_d2wkta2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to hypoxia [GO:0001666]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to hypoxia [GO:0001666]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2gpcb2_d2rcvd2__1				Firmicutes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2gpha__d5ut3a___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; caveola [GO:0005901]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; early endosome [GO:0005769]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; microtubule organizing center [GO:0005815]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; pseudopodium [GO:0031143]; ATP binding [GO:0005524]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; MAP kinase activity [GO:0004707]; MAP kinase kinase activity [GO:0004708]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; phosphatase binding [GO:0019902]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription factor binding [GO:0008134]; aging [GO:0007568]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiac neural crest cell development involved in heart development [GO:0061308]; caveolin-mediated endocytosis [GO:0072584]; cell cycle [GO:0007049]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to organic substance [GO:0071310]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cytosine metabolic process [GO:0019858]; decidualization [GO:0046697]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERBB signaling pathway [GO:0038127]; ERK1 and ERK2 cascade [GO:0070371]; face development [GO:0060324]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; long-term synaptic potentiation [GO:0060291]; lung morphogenesis [GO:0060425]; mammary gland epithelial cell proliferation [GO:0033598]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; outer ear morphogenesis [GO:0042473]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; protein phosphorylation [GO:0006468]; regulation of cellular pH [GO:0030641]; regulation of cytoskeleton organization [GO:0051493]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of gene expression [GO:0010468]; regulation of Golgi inheritance [GO:0090170]; regulation of ossification [GO:0030278]; regulation of protein stability [GO:0031647]; regulation of stress-activated MAPK cascade [GO:0032872]; response to epidermal growth factor [GO:0070849]; response to estrogen [GO:0043627]; response to exogenous dsRNA [GO:0043330]; response to nicotine [GO:0035094]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea formation [GO:0060440]	caveola [GO:0005901]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome lumen [GO:0031904]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; acetylcholine receptor binding [GO:0033130]; ATP binding [GO:0005524]; growth hormone receptor binding [GO:0005131]; heme binding [GO:0020037]; histone binding [GO:0042393]; histone kinase activity (H3-Y41 specific) [GO:0035401]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; interleukin-12 receptor binding [GO:0005143]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; type 1 angiotensin receptor binding [GO:0031702]; actin filament polymerization [GO:0030041]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activation of Janus kinase activity [GO:0042976]; activation of MAPKK activity [GO:0000186]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; axon regeneration [GO:0031103]; blood coagulation [GO:0007596]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; enzyme linked receptor protein signaling pathway [GO:0007167]; erythrocyte differentiation [GO:0030218]; extrinsic apoptotic signaling pathway [GO:0097191]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; histone H3-Y41 phosphorylation [GO:0035409]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; mammary gland epithelium development [GO:0061180]; MAPK cascade [GO:0000165]; mesoderm development [GO:0007498]; microglial cell activation [GO:0001774]; mineralocorticoid receptor signaling pathway [GO:0031959]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of DNA binding [GO:0043392]; negative regulation of heart contraction [GO:0045822]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell activation [GO:0050867]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial cell apoptotic process [GO:1904037]; positive regulation of growth factor dependent skeletal muscle satellite cell proliferation [GO:1902728]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; positive regulation of inflammatory response [GO:0050729]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; postsynapse to nucleus signaling pathway [GO:0099527]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of inflammatory response [GO:0050727]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; response to antibiotic [GO:0046677]; response to hydroperoxide [GO:0033194]; response to interleukin-12 [GO:0070671]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; tyrosine phosphorylation of STAT protein [GO:0007260]	aging [GO:0007568]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiac neural crest cell development involved in heart development [GO:0061308]; caveolin-mediated endocytosis [GO:0072584]; cell cycle [GO:0007049]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to organic substance [GO:0071310]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cytosine metabolic process [GO:0019858]; decidualization [GO:0046697]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERBB signaling pathway [GO:0038127]; ERK1 and ERK2 cascade [GO:0070371]; face development [GO:0060324]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; long-term synaptic potentiation [GO:0060291]; lung morphogenesis [GO:0060425]; mammary gland epithelial cell proliferation [GO:0033598]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; outer ear morphogenesis [GO:0042473]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; protein phosphorylation [GO:0006468]; regulation of cellular pH [GO:0030641]; regulation of cytoskeleton organization [GO:0051493]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of gene expression [GO:0010468]; regulation of Golgi inheritance [GO:0090170]; regulation of ossification [GO:0030278]; regulation of protein stability [GO:0031647]; regulation of stress-activated MAPK cascade [GO:0032872]; response to epidermal growth factor [GO:0070849]; response to estrogen [GO:0043627]; response to exogenous dsRNA [GO:0043330]; response to nicotine [GO:0035094]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea formation [GO:0060440]	actin filament polymerization [GO:0030041]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activation of Janus kinase activity [GO:0042976]; activation of MAPKK activity [GO:0000186]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; axon regeneration [GO:0031103]; blood coagulation [GO:0007596]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; enzyme linked receptor protein signaling pathway [GO:0007167]; erythrocyte differentiation [GO:0030218]; extrinsic apoptotic signaling pathway [GO:0097191]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; histone H3-Y41 phosphorylation [GO:0035409]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; mammary gland epithelium development [GO:0061180]; MAPK cascade [GO:0000165]; mesoderm development [GO:0007498]; microglial cell activation [GO:0001774]; mineralocorticoid receptor signaling pathway [GO:0031959]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of heart contraction [GO:0045822]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell activation [GO:0050867]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial cell apoptotic process [GO:1904037]; positive regulation of growth factor dependent skeletal muscle satellite cell proliferation [GO:1902728]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; positive regulation of inflammatory response [GO:0050729]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; postsynapse to nucleus signaling pathway [GO:0099527]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of inflammatory response [GO:0050727]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; response to antibiotic [GO:0046677]; response to hydroperoxide [GO:0033194]; response to interleukin-12 [GO:0070671]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; tyrosine phosphorylation of STAT protein [GO:0007260]	axon [GO:0030424]; caveola [GO:0005901]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; early endosome [GO:0005769]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; microtubule organizing center [GO:0005815]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; pseudopodium [GO:0031143]	caveola [GO:0005901]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome lumen [GO:0031904]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	ATP binding [GO:0005524]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; MAP kinase activity [GO:0004707]; MAP kinase kinase activity [GO:0004708]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; phosphatase binding [GO:0019902]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription factor binding [GO:0008134]	acetylcholine receptor binding [GO:0033130]; ATP binding [GO:0005524]; growth hormone receptor binding [GO:0005131]; heme binding [GO:0020037]; histone binding [GO:0042393]; histone kinase activity (H3-Y41 specific) [GO:0035401]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; interleukin-12 receptor binding [GO:0005143]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; type 1 angiotensin receptor binding [GO:0031702]
d2gpl1__d1jd2r___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2gpli__d5l68e___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2gplj__d4ltcf___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2gpln__d3c91w1__1	Fungi		Ascomycota	Euryarchaeota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2gpls__d4r17w___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2gplv__d5l5in___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2gplw__d3okjf___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2gppb__d5ixka___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; fibrillar center [GO:0001650]; histone deacetylase complex [GO:0000118]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; androgen receptor binding [GO:0050681]; estrogen receptor binding [GO:0030331]; glucocorticoid receptor binding [GO:0035259]; histone deacetylase binding [GO:0042826]; nuclear hormone receptor binding [GO:0035257]; retinoid X receptor binding [GO:0046965]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; androgen receptor signaling pathway [GO:0030521]; cellular response to estradiol stimulus [GO:0071392]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; lipid storage [GO:0019915]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ovarian follicle rupture [GO:0001543]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	androgen receptor signaling pathway [GO:0030521]; cellular response to estradiol stimulus [GO:0071392]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; lipid storage [GO:0019915]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ovarian follicle rupture [GO:0001543]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; fibrillar center [GO:0001650]; histone deacetylase complex [GO:0000118]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	androgen receptor binding [GO:0050681]; estrogen receptor binding [GO:0030331]; glucocorticoid receptor binding [GO:0035259]; histone deacetylase binding [GO:0042826]; nuclear hormone receptor binding [GO:0035257]; retinoid X receptor binding [GO:0046965]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d2gpra__d1ggra___1			Tenericutes	Proteobacteria	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]; enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]	kinase activity [GO:0016301]; metal ion binding [GO:0046872]	enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]
d2gpsa1_d2vpqa3__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2gpsb1_d2ys7a3__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d2gpvb__d6bn6a___1	Metazoa	Metazoa	Chordata	Chordata	histone deacetylase complex [GO:0000118]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; glucocorticoid receptor binding [GO:0035259]; histone deacetylase binding [GO:0042826]; Notch binding [GO:0005112]; nuclear hormone receptor binding [GO:0035257]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]; estrous cycle [GO:0044849]; lactation [GO:0007595]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072365]; regulation of lipid metabolic process [GO:0019216]; response to estradiol [GO:0032355]; response to organonitrogen compound [GO:0010243]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	estrous cycle [GO:0044849]; lactation [GO:0007595]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072365]; regulation of lipid metabolic process [GO:0019216]; response to estradiol [GO:0032355]; response to organonitrogen compound [GO:0010243]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	histone deacetylase complex [GO:0000118]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; glucocorticoid receptor binding [GO:0035259]; histone deacetylase binding [GO:0042826]; Notch binding [GO:0005112]; nuclear hormone receptor binding [GO:0035257]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d2gpvd__d1ot7b___1	Metazoa	Metazoa	Chordata	Chordata	histone deacetylase complex [GO:0000118]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; glucocorticoid receptor binding [GO:0035259]; histone deacetylase binding [GO:0042826]; Notch binding [GO:0005112]; nuclear hormone receptor binding [GO:0035257]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]; estrous cycle [GO:0044849]; lactation [GO:0007595]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072365]; regulation of lipid metabolic process [GO:0019216]; response to estradiol [GO:0032355]; response to organonitrogen compound [GO:0010243]	nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]; bile acid binding [GO:0032052]; bile acid receptor activity [GO:0038181]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; bile acid metabolic process [GO:0008206]; bile acid signaling pathway [GO:0038183]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; digestive tract development [GO:0048565]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; multicellular organism development [GO:0007275]; negative regulation of inflammatory response [GO:0050728]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of carbohydrate metabolic process [GO:0006109]; response to glucose [GO:0009749]; response to lipopolysaccharide [GO:0032496]	estrous cycle [GO:0044849]; lactation [GO:0007595]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072365]; regulation of lipid metabolic process [GO:0019216]; response to estradiol [GO:0032355]; response to organonitrogen compound [GO:0010243]	bile acid metabolic process [GO:0008206]; bile acid signaling pathway [GO:0038183]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; digestive tract development [GO:0048565]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; multicellular organism development [GO:0007275]; negative regulation of inflammatory response [GO:0050728]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of carbohydrate metabolic process [GO:0006109]; response to glucose [GO:0009749]; response to lipopolysaccharide [GO:0032496]	histone deacetylase complex [GO:0000118]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]	nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]	chromatin binding [GO:0003682]; glucocorticoid receptor binding [GO:0035259]; histone deacetylase binding [GO:0042826]; Notch binding [GO:0005112]; nuclear hormone receptor binding [GO:0035257]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]	bile acid binding [GO:0032052]; bile acid receptor activity [GO:0038181]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]
d2gpwa2_d1jdbk3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2gpwb1_d4rzqa3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2gpwc2_d5m8gf1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d2gpwd2_d1m6va3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2gpwd2_d2ys6a1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d2gqaa__d1jueb___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d2gqda1_d5wx7d1__1		Viridiplantae	Firmicutes	Streptophyta	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]	biosynthetic process [GO:0009058]			beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2gqdb1_d1u0wd2__1		Viridiplantae	Firmicutes	Streptophyta	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]			beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	naringenin-chalcone synthase activity [GO:0016210]
d2gqha1_d3okda1__1	Metazoa		Chordata		cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]		G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]		cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]		ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	
d2gqka1_d2fchb___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; copper ion binding [GO:0005507]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	copper ion binding [GO:0005507]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2gqma1_d5ey6b1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; copper ion binding [GO:0005507]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cytoplasm [GO:0005737]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]	cytoplasm [GO:0005737]	copper ion binding [GO:0005507]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2gqna__d2dgkf___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; methionine biosynthetic process [GO:0009086]; transsulfuration [GO:0019346]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	methionine biosynthetic process [GO:0009086]; transsulfuration [GO:0019346]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]
d2gqnb__d1c7od___1			Proteobacteria	Spirochaetes	cytoplasm [GO:0005737]; cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; methionine biosynthetic process [GO:0009086]; transsulfuration [GO:0019346]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	methionine biosynthetic process [GO:0009086]; transsulfuration [GO:0019346]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]		cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d2gqwa3_d3q6jb3__1			Proteobacteria	Proteobacteria	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; 2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]		cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]		cell [GO:0005623]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]	2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]
d2gqxb__d1jfca___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2gr0a3_d1jeha3__1		Fungi	Proteobacteria	Ascomycota	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; glycine cleavage complex [GO:0005960]; mitochondrial nucleoid [GO:0042645]; mitochondrial oxoglutarate dehydrogenase complex [GO:0009353]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glycine dehydrogenase (decarboxylating) activity [GO:0004375]; oxoglutarate dehydrogenase (succinyl-transferring) activity [GO:0004591]; pyruvate dehydrogenase activity [GO:0004738]; 2-oxoglutarate metabolic process [GO:0006103]; cell redox homeostasis [GO:0045454]; glycine catabolic process [GO:0006546]; hydrogen peroxide metabolic process [GO:0042743]; isoleucine catabolic process [GO:0006550]; L-serine biosynthetic process [GO:0006564]; leucine catabolic process [GO:0006552]; pyruvate metabolic process [GO:0006090]; valine catabolic process [GO:0006574]		2-oxoglutarate metabolic process [GO:0006103]; cell redox homeostasis [GO:0045454]; glycine catabolic process [GO:0006546]; hydrogen peroxide metabolic process [GO:0042743]; isoleucine catabolic process [GO:0006550]; leucine catabolic process [GO:0006552]; L-serine biosynthetic process [GO:0006564]; pyruvate metabolic process [GO:0006090]; valine catabolic process [GO:0006574]		cell [GO:0005623]; glycine cleavage complex [GO:0005960]; mitochondrial nucleoid [GO:0042645]; mitochondrial oxoglutarate dehydrogenase complex [GO:0009353]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]	dihydrolipoyl dehydrogenase activity [GO:0004148]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glycine dehydrogenase (decarboxylating) activity [GO:0004375]; oxoglutarate dehydrogenase (succinyl-transferring) activity [GO:0004591]; pyruvate dehydrogenase activity [GO:0004738]
d2gr1a2_d2jk6a2__1			Proteobacteria		flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]
d2gr2a3_d2c3cb3__1			Proteobacteria	Proteobacteria	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; 2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]; cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]		cell redox homeostasis [GO:0045454]; propylene catabolic process [GO:0042208]		cell [GO:0005623]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]	2-oxopropyl-CoM reductase (carboxylating) activity [GO:0050628]; flavin adenine dinucleotide binding [GO:0050660]
d2gr9d1_d1bsva___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	cytoplasm [GO:0005737]; GDP-L-fucose synthase activity [GO:0050577]; isomerase activity [GO:0016853]; NADP+ binding [GO:0070401]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; colanic acid biosynthetic process [GO:0009242]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; colanic acid biosynthetic process [GO:0009242]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]	GDP-L-fucose synthase activity [GO:0050577]; isomerase activity [GO:0016853]; NADP+ binding [GO:0070401]
d2grae1_d3vpfd1__1	Metazoa		Chordata		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]		cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]	
d2grha__d1cioa1__1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2grhb__d5urcb___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2grlb1_d1rper___1			Firmicutes		transcriptional repressor complex [GO:0017053]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]	negative regulation of transcription, DNA-templated [GO:0045892]		transcriptional repressor complex [GO:0017053]		DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2grmb1_d2ivqa1__1				Proteobacteria		cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]		cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2grza__d1yhui___1	Metazoa	Metazoa	Mollusca	Annelida	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2grza__d4rolb___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2gsgb1_d1uz8a1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2gsgb1_d5tztb2__1		Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; thrombospondin receptor activity [GO:0070053]; cell migration [GO:0016477]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; neutrophil degranulation [GO:0043312]; opsonization [GO:0008228]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of inflammatory response [GO:0050729]; positive regulation of phagocytosis [GO:0050766]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell activation [GO:0050870]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-10 production [GO:0032653]; regulation of interleukin-12 production [GO:0032655]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]; response to bacterium [GO:0009617]		cell migration [GO:0016477]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; neutrophil degranulation [GO:0043312]; opsonization [GO:0008228]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of inflammatory response [GO:0050729]; positive regulation of phagocytosis [GO:0050766]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell activation [GO:0050870]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-10 production [GO:0032653]; regulation of interleukin-12 production [GO:0032655]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]; response to bacterium [GO:0009617]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; thrombospondin receptor activity [GO:0070053]
d2gsgd1_d5nmli1__1												
d2gsia2_d3cxhv___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	extracellular region [GO:0005576]; membrane [GO:0016020]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	
d2gsie1_d1fngd1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	extracellular region [GO:0005576]; membrane [GO:0016020]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	
d2gsih1_d1kb9k___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	extracellular region [GO:0005576]; membrane [GO:0016020]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	
d2gsih1_d5uy3l1__1			Firmicutes		extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]				extracellular region [GO:0005576]; membrane [GO:0016020]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	
d2gsmb1_d2iwkb2__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]		denitrification pathway [GO:0019333]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	membrane [GO:0016020]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d2gsmd1_d1ilua___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2gspa__d3wr2b___1	Fungi	Fungi	Ascomycota	Basidiomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]		endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d2gsqa1_d4dejh2__1	Metazoa		Mollusca	Proteobacteria	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]			cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d2gsra2_d1egra___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; electron transfer activity [GO:0009055]; nucleotide binding [GO:0000166]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cell [GO:0005623]	glutathione transferase activity [GO:0004364]	electron transfer activity [GO:0009055]; nucleotide binding [GO:0000166]; protein disulfide oxidoreductase activity [GO:0015035]
d2gsrb1_d4deje2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	transferase activity [GO:0016740]	glutathione metabolic process [GO:0006749]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d2gssb1_d1gula1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2gsta1_d1vf3b2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	glutathione transferase activity [GO:0004364]
d2gstb1_d1xw6c1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d2gstb2_d4evma___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cell [GO:0005623]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	oxidoreductase activity [GO:0016491]
d2gsyf__d2bbva___1					host cell cytoplasm [GO:0030430]; T=13 icosahedral viral capsid [GO:0039621]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]	T=3 icosahedral viral capsid [GO:0039617]; aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]			host cell cytoplasm [GO:0030430]; T=13 icosahedral viral capsid [GO:0039621]	T=3 icosahedral viral capsid [GO:0039617]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]
d2gt9a2_d1efxa2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2gt9b2_d5e5ud2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; toxin transport [GO:1901998]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; toxin transport [GO:1901998]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]
d2gt9d1_d1uz8h1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2gt9d2_d5wl1a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2gt9e2_d3qxtb___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2gtda1_d1yxqb2__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	coenzyme A biosynthetic process [GO:0015937]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2gtdb1_d1tuub2__1			Thermotogae	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	coenzyme A biosynthetic process [GO:0015937]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]
d2gtdb1_d3bf3f2__1			Thermotogae	Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d2gtdc2_d3fzma2__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	coenzyme A biosynthetic process [GO:0015937]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d2gtde1_d1dgkn1__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	coenzyme A biosynthetic process [GO:0015937]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d2gtdf2_d3bf3c1__1			Thermotogae	Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d2gtdf2_d3ldpa1__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	coenzyme A biosynthetic process [GO:0015937]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	cytoplasm [GO:0005737]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d2gteb__d2wcma___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	odorant binding [GO:0005549]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]		dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]	odorant binding [GO:0005549]
d2gtfx2_d2l67a___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	vasodilation [GO:0042311]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]
d2gtha1_d1p1bc___1		Metazoa		Chordata	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]	transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]	guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d2gtlc1_d3wcwc___1	Metazoa	Metazoa	Annelida	Annelida	metal ion binding [GO:0046872]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	metal ion binding [GO:0046872]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2gtlg1_d1liaa___1	Metazoa		Annelida	Rhodophyta	metal ion binding [GO:0046872]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	metal ion binding [GO:0046872]	
d2gtlj1_d3s1ic___1	Metazoa		Annelida	Verrucomicrobia	metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2gtll1_d3gdja___1	Metazoa	Metazoa	Annelida	Chordata	metal ion binding [GO:0046872]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2gtlm1_d2gtlo1__1	Metazoa	Metazoa	Annelida	Annelida	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2gtpd__d2i59a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; leukotriene signaling pathway [GO:0061737]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]	axon terminus [GO:0043679]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to amphetamine [GO:0001975]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; leukotriene signaling pathway [GO:0061737]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]	G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to amphetamine [GO:0001975]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]	axon terminus [GO:0043679]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	calmodulin binding [GO:0005516]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]
d2gtra__d3h0ub___1	Metazoa		Chordata	Actinobacteria	chromosome [GO:0005694]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; crotonyl-CoA hydratase activity [GO:0120092]; methylated histone binding [GO:0035064]; protein binding, bridging [GO:0030674]; transcription corepressor activity [GO:0003714]; negative regulation of peptidyl-lysine crotonylation [GO:0120094]; random inactivation of X chromosome [GO:0060816]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]	catalytic activity [GO:0003824]	negative regulation of peptidyl-lysine crotonylation [GO:0120094]; random inactivation of X chromosome [GO:0060816]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]		chromosome [GO:0005694]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleus [GO:0005634]		chromatin binding [GO:0003682]; crotonyl-CoA hydratase activity [GO:0120092]; methylated histone binding [GO:0035064]; protein binding, bridging [GO:0030674]; transcription corepressor activity [GO:0003714]	catalytic activity [GO:0003824]
d2gtua1_d5j5nb2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytoplasm [GO:0005737]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione transferase activity [GO:0004364]
d2gtua2_d2a2sa2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2gtub2_d3ik9c1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2gtwa1_d5w1wo1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2gtwa2_d5u2va1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2gtwb2_d1p4ih___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2gtwd1_d5x8ln1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2gtza1_d3ha0a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2gtze2_d4grwi___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]; cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d2guia__d1c0ma2__1			Proteobacteria		cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; DNA replication proofreading [GO:0045004]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; reverse transcription [GO:0001171]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA replication proofreading [GO:0045004]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; reverse transcription [GO:0001171]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]	viral nucleocapsid [GO:0019013]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d2guod1_d1s78e2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]
d2gv1a__d4oj3b___1			Proteobacteria	Crenarchaeota	acylphosphatase activity [GO:0003998]; response to heat [GO:0009408]	acylphosphatase activity [GO:0003998]	response to heat [GO:0009408]				acylphosphatase activity [GO:0003998]	acylphosphatase activity [GO:0003998]
d2gv7a__d3ruob1__1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2gvcb2_d1grga2__1	Fungi	Metazoa	Ascomycota	Chordata	endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; monooxygenase activity [GO:0004497]; N,N-dimethylaniline monooxygenase activity [GO:0004499]; NADP binding [GO:0050661]; protein folding in endoplasmic reticulum [GO:0034975]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	protein folding in endoplasmic reticulum [GO:0034975]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; monooxygenase activity [GO:0004497]; N,N-dimethylaniline monooxygenase activity [GO:0004499]; NADP binding [GO:0050661]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]
d2gvpa1_d2h70b___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; copper ion binding [GO:0005507]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	copper ion binding [GO:0005507]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2gvqc1_d2wk6b1__1		Metazoa	Crenarchaeota	Chordata	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	tryptophan biosynthetic process [GO:0000162]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	cytosol [GO:0005829]	cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d2gvqd1_d4xr5a1__1			Crenarchaeota	Proteobacteria	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]	tryptophan biosynthetic process [GO:0000162]	pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]	cytosol [GO:0005829]	cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d2gvxa__d3srga___1	Metazoa		Mollusca		calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]						calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	
d2gvya1_d1xh2a1__1	Fungi	Metazoa	Ascomycota	Chordata	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate catabolic process [GO:0016052]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d2gwfc2_d3olha2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; perinuclear region of cytoplasm [GO:0048471]; erythropoietin receptor binding [GO:0005128]; interleukin-3 receptor binding [GO:0005135]; protein domain specific binding [GO:0019904]; Ral GTPase binding [GO:0017160]; receptor tyrosine kinase binding [GO:0030971]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitophagy [GO:1901525]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; proteasomal protein catabolic process [GO:0010498]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of establishment of cell polarity [GO:2000114]; regulation of lymphocyte differentiation [GO:0045619]; regulation of MAPK cascade [GO:0043408]; regulation of myeloid cell differentiation [GO:0045637]; regulation of protein kinase B signaling [GO:0051896]; regulation of reactive oxygen species metabolic process [GO:2000377]	cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; synapse [GO:0045202]; 3-mercaptopyruvate sulfurtransferase activity [GO:0016784]; identical protein binding [GO:0042802]; thiosulfate sulfurtransferase activity [GO:0004792]; cyanate catabolic process [GO:0009440]; hydrogen sulfide biosynthetic process [GO:0070814]; kidney development [GO:0001822]; liver development [GO:0001889]; response to toxic substance [GO:0009636]; spinal cord development [GO:0021510]; sulfur amino acid catabolic process [GO:0000098]; transsulfuration [GO:0019346]	autophagy [GO:0006914]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitophagy [GO:1901525]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; proteasomal protein catabolic process [GO:0010498]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of establishment of cell polarity [GO:2000114]; regulation of lymphocyte differentiation [GO:0045619]; regulation of MAPK cascade [GO:0043408]; regulation of myeloid cell differentiation [GO:0045637]; regulation of protein kinase B signaling [GO:0051896]; regulation of reactive oxygen species metabolic process [GO:2000377]	cyanate catabolic process [GO:0009440]; hydrogen sulfide biosynthetic process [GO:0070814]; kidney development [GO:0001822]; liver development [GO:0001889]; response to toxic substance [GO:0009636]; spinal cord development [GO:0021510]; sulfur amino acid catabolic process [GO:0000098]; transsulfuration [GO:0019346]	cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; perinuclear region of cytoplasm [GO:0048471]	cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; synapse [GO:0045202]	erythropoietin receptor binding [GO:0005128]; interleukin-3 receptor binding [GO:0005135]; protein domain specific binding [GO:0019904]; Ral GTPase binding [GO:0017160]; receptor tyrosine kinase binding [GO:0030971]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	3-mercaptopyruvate sulfurtransferase activity [GO:0016784]; identical protein binding [GO:0042802]; thiosulfate sulfurtransferase activity [GO:0004792]
d2gwfe2_d1urhb1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; perinuclear region of cytoplasm [GO:0048471]; erythropoietin receptor binding [GO:0005128]; interleukin-3 receptor binding [GO:0005135]; protein domain specific binding [GO:0019904]; Ral GTPase binding [GO:0017160]; receptor tyrosine kinase binding [GO:0030971]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitophagy [GO:1901525]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; proteasomal protein catabolic process [GO:0010498]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of establishment of cell polarity [GO:2000114]; regulation of lymphocyte differentiation [GO:0045619]; regulation of MAPK cascade [GO:0043408]; regulation of myeloid cell differentiation [GO:0045637]; regulation of protein kinase B signaling [GO:0051896]; regulation of reactive oxygen species metabolic process [GO:2000377]	cytosol [GO:0005829]; 3-mercaptopyruvate sulfurtransferase activity [GO:0016784]; thiosulfate sulfurtransferase activity [GO:0004792]; DNA protection [GO:0042262]; response to antibiotic [GO:0046677]; response to oxidative stress [GO:0006979]; transsulfuration [GO:0019346]	autophagy [GO:0006914]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitophagy [GO:1901525]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; proteasomal protein catabolic process [GO:0010498]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of establishment of cell polarity [GO:2000114]; regulation of lymphocyte differentiation [GO:0045619]; regulation of MAPK cascade [GO:0043408]; regulation of myeloid cell differentiation [GO:0045637]; regulation of protein kinase B signaling [GO:0051896]; regulation of reactive oxygen species metabolic process [GO:2000377]	DNA protection [GO:0042262]; response to antibiotic [GO:0046677]; response to oxidative stress [GO:0006979]; transsulfuration [GO:0019346]	cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; perinuclear region of cytoplasm [GO:0048471]	cytosol [GO:0005829]	erythropoietin receptor binding [GO:0005128]; interleukin-3 receptor binding [GO:0005135]; protein domain specific binding [GO:0019904]; Ral GTPase binding [GO:0017160]; receptor tyrosine kinase binding [GO:0030971]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	3-mercaptopyruvate sulfurtransferase activity [GO:0016784]; thiosulfate sulfurtransferase activity [GO:0004792]
d2gwkb2_d1qhaa3__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d2gwoa__d1zzwb___1	Metazoa	Metazoa	Chordata	Chordata	phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dephosphorylation [GO:0016311]; meiotic cell cycle [GO:0051321]; protein dephosphorylation [GO:0006470]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; JUN kinase binding [GO:0008432]; MAP kinase phosphatase activity [GO:0033549]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; mitogen-activated protein kinase p38 binding [GO:0048273]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelium regeneration [GO:1905042]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; oligodendrocyte differentiation [GO:0048709]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein dephosphorylation [GO:0006470]; regulation of adaptive immune response [GO:0002819]; regulation of brown fat cell differentiation [GO:0090335]; response to lipopolysaccharide [GO:0032496]	dephosphorylation [GO:0016311]; meiotic cell cycle [GO:0051321]; protein dephosphorylation [GO:0006470]; spermatogenesis [GO:0007283]	dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelium regeneration [GO:1905042]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; oligodendrocyte differentiation [GO:0048709]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein dephosphorylation [GO:0006470]; regulation of adaptive immune response [GO:0002819]; regulation of brown fat cell differentiation [GO:0090335]; response to lipopolysaccharide [GO:0032496]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	JUN kinase binding [GO:0008432]; MAP kinase phosphatase activity [GO:0033549]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; mitogen-activated protein kinase p38 binding [GO:0048273]; phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; protein tyrosine phosphatase activity [GO:0004725]
d2gwod__d2f6wa___1	Metazoa	Metazoa	Chordata	Chordata	phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dephosphorylation [GO:0016311]; meiotic cell cycle [GO:0051321]; protein dephosphorylation [GO:0006470]; spermatogenesis [GO:0007283]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	dephosphorylation [GO:0016311]; meiotic cell cycle [GO:0051321]; protein dephosphorylation [GO:0006470]; spermatogenesis [GO:0007283]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]		cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2gwsa1_d1zqja1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d2gwsa1_d4iqwa1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2gwsa3_d1sz1a2__1	Metazoa		Chordata	Euryarchaeota	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]		5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]
d2gwse1_d4i2ga1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2gwsi1_d3rjha1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d2gwsi3_d2o1pa2__1	Metazoa	Fungi	Chordata	Ascomycota	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d2gwsm3_d4klia3__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d2gx4a__d1lvod___1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2gxqa__d2h1li___1		Metazoa	Deinococcus-Thermus	Chordata	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]		autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d2gxqa__d4kyih___1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	hydrolase activity [GO:0016787]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]			ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	hydrolase activity [GO:0016787]
d2gxsa__d2j59c2__1		Metazoa	Deinococcus-Thermus	Chordata	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; GTPase activator activity [GO:0005096]; establishment of Golgi localization [GO:0051683]; Golgi organization [GO:0007030]; maintenance of Golgi location [GO:0051684]; organelle transport along microtubule [GO:0072384]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]		establishment of Golgi localization [GO:0051683]; Golgi organization [GO:0007030]; maintenance of Golgi location [GO:0051684]; organelle transport along microtubule [GO:0072384]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]		actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	GTPase activator activity [GO:0005096]
d2gy9d1_d1i95d___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2gy9i1_d2npfb3__1		Fungi		Ascomycota		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]
d2gyah1_d1vqkj1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2gyan1_d2j28p1__1				Proteobacteria		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]		5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]
d2gybt1_d2f4vt1__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2gyka1_d2no8a___1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	protein-containing complex [GO:0032991]		protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	toxic substance binding [GO:0015643]
d2gykb__d2vnda___1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	extracellular region [GO:0005576]; deoxyribonuclease activity [GO:0004536]; endonuclease activity [GO:0004519]; DNA catabolic process [GO:0006308]	bacteriocin immunity [GO:0030153]	DNA catabolic process [GO:0006308]	protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	deoxyribonuclease activity [GO:0004536]; endonuclease activity [GO:0004519]
d2gyoa1_d1xpka2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	isoprenoid biosynthetic process [GO:0008299]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d2gyqb__d3a9qh___1		Viridiplantae	Proteobacteria	Streptophyta	metal ion binding [GO:0046872]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2gysa1_d4n68a1__1	Metazoa	Metazoa	Chordata	Chordata	granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; signaling receptor activity [GO:0038023]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-3 [GO:0036016]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-3-mediated signaling pathway [GO:0038156]; interleukin-5-mediated signaling pathway [GO:0038043]; MAPK cascade [GO:0000165]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]	anchored component of presynaptic membrane [GO:0099026]; extracellular region [GO:0005576]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]; cell adhesion [GO:0007155]; presynapse assembly [GO:0099054]; sensory perception of sound [GO:0007605]	cellular protein metabolic process [GO:0044267]; cellular response to interleukin-3 [GO:0036016]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-3-mediated signaling pathway [GO:0038156]; interleukin-5-mediated signaling pathway [GO:0038043]; MAPK cascade [GO:0000165]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]	cell adhesion [GO:0007155]; presynapse assembly [GO:0099054]; sensory perception of sound [GO:0007605]	granulocyte macrophage colony-stimulating factor receptor complex [GO:0030526]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	anchored component of presynaptic membrane [GO:0099026]; extracellular region [GO:0005576]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]	cytokine receptor activity [GO:0004896]; signaling receptor activity [GO:0038023]	
d2gyya2_d4dbvr2__1			Firmicutes	Firmicutes	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2gyyb2_d1ml3d2__1			Firmicutes		aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		glycosome [GO:0020015]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2gz1a2_d2egha3__1			Firmicutes	Proteobacteria	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]			aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]
d2gz3c2_d4dbvq2__1			Firmicutes	Firmicutes	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2gz7a__d2bdik___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2gz9a__d1o0d.1__1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d2gz9a__d5c5na___1					cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2gzba1_d3n7ma2__1	Viridiplantae		Streptophyta	Firmicutes	extracellular region [GO:0005576]; cysteine-type endopeptidase inhibitor activity [GO:0004869]	extracellular region [GO:0005576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]		negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cysteine-type endopeptidase inhibitor activity [GO:0004869]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]
d2gzeb__d1v15c___1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	extrachromosomal circular DNA [GO:0005727]; protein-containing complex [GO:0032991]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; pathogenesis [GO:0009405]	bacteriocin immunity [GO:0030153]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; pathogenesis [GO:0009405]	protein-containing complex [GO:0032991]	extrachromosomal circular DNA [GO:0005727]; protein-containing complex [GO:0032991]	protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]
d2gzeb__d4qkoh___1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	bacteriocin immunity [GO:0030153]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	protein-containing complex [GO:0032991]		protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]
d2gzfa__d4uhpf1__1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	protein-containing complex [GO:0032991]		protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	toxic substance binding [GO:0015643]
d2gzib__d2ivkb___1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	endonuclease activity [GO:0004519]	bacteriocin immunity [GO:0030153]		protein-containing complex [GO:0032991]		protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	endonuclease activity [GO:0004519]
d2gzje__d1unka___1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	protein-containing complex [GO:0032991]		protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	toxic substance binding [GO:0015643]
d2gzoa1_d2muia___1			Proteobacteria	Proteobacteria								
d2gztc__d4ok9a___1				Firmicutes		mRNA binding [GO:0003729]; histidine metabolic process [GO:0006547]; positive regulation of gene expression [GO:0010628]		histidine metabolic process [GO:0006547]; positive regulation of gene expression [GO:0010628]				mRNA binding [GO:0003729]
d2gzwa1_d3wu1b___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2gzwa2_d4byya1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2gzwd1_d3e5xb2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]
d2gzya__d1xcca___1			Firmicutes	Apicomplexa	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peroxiredoxin activity [GO:0051920]
d2h01a1_d2fug21__1			Apicomplexa	Deinococcus-Thermus	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]	plasma membrane [GO:0005886]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	quinone binding [GO:0048038]
d2h06b1_d1bzya___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; adenine salvage [GO:0006168]; central nervous system neuron development [GO:0021954]; cerebral cortex neuron differentiation [GO:0021895]; dendrite morphogenesis [GO:0048813]; dopamine metabolic process [GO:0042417]; GMP catabolic process [GO:0046038]; GMP salvage [GO:0032263]; grooming behavior [GO:0007625]; guanine salvage [GO:0006178]; hypoxanthine metabolic process [GO:0046100]; hypoxanthine salvage [GO:0043103]; IMP metabolic process [GO:0046040]; IMP salvage [GO:0032264]; locomotory behavior [GO:0007626]; lymphocyte proliferation [GO:0046651]; positive regulation of dopamine metabolic process [GO:0045964]; protein homotetramerization [GO:0051289]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside salvage [GO:0006166]; purine-containing compound salvage [GO:0043101]; response to amphetamine [GO:0001975]; striatum development [GO:0021756]; T cell mediated cytotoxicity [GO:0001913]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	adenine salvage [GO:0006168]; central nervous system neuron development [GO:0021954]; cerebral cortex neuron differentiation [GO:0021895]; dendrite morphogenesis [GO:0048813]; dopamine metabolic process [GO:0042417]; GMP catabolic process [GO:0046038]; GMP salvage [GO:0032263]; grooming behavior [GO:0007625]; guanine salvage [GO:0006178]; hypoxanthine metabolic process [GO:0046100]; hypoxanthine salvage [GO:0043103]; IMP metabolic process [GO:0046040]; IMP salvage [GO:0032264]; locomotory behavior [GO:0007626]; lymphocyte proliferation [GO:0046651]; positive regulation of dopamine metabolic process [GO:0045964]; protein homotetramerization [GO:0051289]; purine-containing compound salvage [GO:0043101]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside salvage [GO:0006166]; response to amphetamine [GO:0001975]; striatum development [GO:0021756]; T cell mediated cytotoxicity [GO:0001913]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]
d2h07a1_d1qcca___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	adenine phosphoribosyltransferase activity [GO:0003999]; nucleotide binding [GO:0000166]; nucleoside metabolic process [GO:0009116]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]	adenine phosphoribosyltransferase activity [GO:0003999]; nucleotide binding [GO:0000166]
d2h07a1_d3mbid2__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]
d2h07b1_d3ggja___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; adenine salvage [GO:0006168]; central nervous system neuron development [GO:0021954]; cerebral cortex neuron differentiation [GO:0021895]; dendrite morphogenesis [GO:0048813]; dopamine metabolic process [GO:0042417]; GMP catabolic process [GO:0046038]; GMP salvage [GO:0032263]; grooming behavior [GO:0007625]; guanine salvage [GO:0006178]; hypoxanthine metabolic process [GO:0046100]; hypoxanthine salvage [GO:0043103]; IMP metabolic process [GO:0046040]; IMP salvage [GO:0032264]; locomotory behavior [GO:0007626]; lymphocyte proliferation [GO:0046651]; positive regulation of dopamine metabolic process [GO:0045964]; protein homotetramerization [GO:0051289]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside salvage [GO:0006166]; purine-containing compound salvage [GO:0043101]; response to amphetamine [GO:0001975]; striatum development [GO:0021756]; T cell mediated cytotoxicity [GO:0001913]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	adenine salvage [GO:0006168]; central nervous system neuron development [GO:0021954]; cerebral cortex neuron differentiation [GO:0021895]; dendrite morphogenesis [GO:0048813]; dopamine metabolic process [GO:0042417]; GMP catabolic process [GO:0046038]; GMP salvage [GO:0032263]; grooming behavior [GO:0007625]; guanine salvage [GO:0006178]; hypoxanthine metabolic process [GO:0046100]; hypoxanthine salvage [GO:0043103]; IMP metabolic process [GO:0046040]; IMP salvage [GO:0032264]; locomotory behavior [GO:0007626]; lymphocyte proliferation [GO:0046651]; positive regulation of dopamine metabolic process [GO:0045964]; protein homotetramerization [GO:0051289]; purine-containing compound salvage [GO:0043101]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside salvage [GO:0006166]; response to amphetamine [GO:0001975]; striatum development [GO:0021756]; T cell mediated cytotoxicity [GO:0001913]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]
d2h08a1_d3efhb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]
d2h0gb1_d4ilfa2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	cell [GO:0005623]; periplasmic space [GO:0042597]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]	periplasmic space [GO:0042597]	cell [GO:0005623]; periplasmic space [GO:0042597]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	
d2h0ha1_d3p7xd___1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]	periplasmic space [GO:0042597]	cell [GO:0005623]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	thioredoxin peroxidase activity [GO:0008379]
d2h0ib1_d1eejb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]	periplasmic space [GO:0042597]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d2h0ma__d1bc1a___1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]
d2h0pa__d1rq5a2__1				Firmicutes	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d2h12c__d6cscb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; citrate (Si)-synthase activity [GO:0004108]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]; carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	citrate (Si)-synthase activity [GO:0004108]	citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]
d2h12e__d2r26b___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; citrate (Si)-synthase activity [GO:0004108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	citrate (Si)-synthase activity [GO:0004108]	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]
d2h19a__d1kyga___1			Firmicutes		cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]		cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]		cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]	
d2h1ab__d2x64a1__1			Firmicutes	Proteobacteria	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	transferase activity [GO:0016740]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]		cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]	transferase activity [GO:0016740]
d2h1ba__d1ep7a___1		Viridiplantae	Firmicutes	Chlorophyta	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell [GO:0005623]; cytoplasm [GO:0005737]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]	protein disulfide oxidoreductase activity [GO:0015035]
d2h1da__d3kijc___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	endoplasmic reticulum lumen [GO:0005788]; integral component of membrane [GO:0016021]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	endoplasmic reticulum lumen [GO:0005788]; integral component of membrane [GO:0016021]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]	glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]
d2h1db__d4is0a1__1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d2h1le__d2awnb2__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]; activating transcription factor binding [GO:0033613]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	activating transcription factor binding [GO:0033613]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; ATP binding [GO:0005524]
d2h1lh__d1iqpb2__1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]
d2h1ll__d1iqpf2__1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]
d2h1ln2_d2o93o2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d2h1ls2_d1e50g___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; chondrocyte differentiation [GO:0002062]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; peripheral nervous system neuron development [GO:0048935]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytokine-mediated signaling pathway [GO:0001959]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of keratinocyte differentiation [GO:0045616]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of myeloid cell differentiation [GO:0045637]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of Wnt signaling pathway [GO:0030111]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	chondrocyte differentiation [GO:0002062]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; peripheral nervous system neuron development [GO:0048935]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytokine-mediated signaling pathway [GO:0001959]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of keratinocyte differentiation [GO:0045616]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of myeloid cell differentiation [GO:0045637]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of Wnt signaling pathway [GO:0030111]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2h1lw2_d1co1a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; chondrocyte differentiation [GO:0002062]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; peripheral nervous system neuron development [GO:0048935]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytokine-mediated signaling pathway [GO:0001959]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of keratinocyte differentiation [GO:0045616]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of myeloid cell differentiation [GO:0045637]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of Wnt signaling pathway [GO:0030111]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	chondrocyte differentiation [GO:0002062]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; peripheral nervous system neuron development [GO:0048935]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytokine-mediated signaling pathway [GO:0001959]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of keratinocyte differentiation [GO:0045616]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of myeloid cell differentiation [GO:0045637]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of Wnt signaling pathway [GO:0030111]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2h1lx2_d3wtxa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]
d2h1oa1_d1ut5a2__1			Proteobacteria		DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]; migration in host [GO:0044001]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; exodeoxyribonuclease activity [GO:0004529]; metal ion binding [GO:0046872]; DNA replication, Okazaki fragment processing [GO:0033567]; viral DNA genome replication [GO:0039693]	migration in host [GO:0044001]	DNA replication, Okazaki fragment processing [GO:0033567]; viral DNA genome replication [GO:0039693]			DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; exodeoxyribonuclease activity [GO:0004529]; metal ion binding [GO:0046872]
d2h1pl2_d3mxvl1__1												
d2h1ua__d1o33a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2h1ua__d2cgga___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]		elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	
d2h1va__d3m4za___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]	heme biosynthetic process [GO:0006783]	heme biosynthetic process [GO:0006783]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]	ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]
d2h1xa__d3iwva___1	Metazoa	Metazoa	Chordata	Chordata	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d2h1xd__d2g2nb___1	Metazoa		Chordata	Proteobacteria	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]	peroxisome [GO:0005777]	periplasmic space [GO:0042597]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]
d2h25a__d1mxva___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2h26b__d1ogad2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2h26b__d4bswb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2h2jb2_d3kmaa___1	Viridiplantae		Streptophyta		chloroplast [GO:0009507]; [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity [GO:0030785]	identical protein binding [GO:0042802]; methyltransferase activity [GO:0008168]			chloroplast [GO:0009507]		[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity [GO:0030785]	identical protein binding [GO:0042802]; methyltransferase activity [GO:0008168]
d2h2pf1_d2jell2__1	Metazoa		Chordata	Proteobacteria		cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]; enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]		phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]		cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]		enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]
d2h2pf2_d1fpth2__1	Metazoa	Metazoa	Chordata	Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2h2pf2_d3darb___1	Metazoa	Metazoa	Chordata	Chordata		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]		angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2h2ra__d1ixxa___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]
d2h2rb__d1b08a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d2h2rb__d4qkhb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; regulation of immune response [GO:0050776]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	cell surface receptor signaling pathway [GO:0007166]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]
d2h2sf1_d5d7ke2__1	Metazoa		Chordata									
d2h32a__d5l21b___1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; membrane [GO:0016020]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	negative regulation of neurotransmitter secretion [GO:0046929]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; membrane [GO:0016020]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d2h33a1_d1fqjb___1		Metazoa		Chordata		cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]		adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]		cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d2h33a1_d2a72b1__1		Metazoa		Chordata		cytosol [GO:0005829]; plasma membrane [GO:0005886]; G-protein beta-subunit binding [GO:0031681]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; protein folding [GO:0006457]		G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; protein folding [GO:0006457]		cytosol [GO:0005829]; plasma membrane [GO:0005886]		G-protein beta-subunit binding [GO:0031681]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]
d2h35b__d4sdha___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2h35d__d1ch4c___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2h3gx1_d1qhab4__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	coenzyme A biosynthetic process [GO:0015937]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d2h3gx1_d4czmb1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	coenzyme A biosynthetic process [GO:0015937]	cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]
d2h3hb__d1uskd___1			Thermotogae	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]; leucine binding [GO:0070728]; leucine transport [GO:0015820]		leucine transport [GO:0015820]	outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]		leucine binding [GO:0070728]
d2h3lb__d1wjla1__1	Metazoa	Metazoa	Chordata	Chordata	basal plasma membrane [GO:0009925]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; hemidesmosome [GO:0030056]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ErbB-2 class receptor binding [GO:0005176]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]; basal protein localization [GO:0045175]; cell adhesion [GO:0007155]; cellular response to tumor necrosis factor [GO:0071356]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165]	cell-cell adherens junction [GO:0005913]; cytoskeleton [GO:0005856]; filamentous actin [GO:0031941]; perinuclear region of cytoplasm [GO:0048471]; pseudopodium [GO:0031143]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cytoskeletal protein binding [GO:0008092]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase C binding [GO:0005080]; actin cytoskeleton organization [GO:0030036]; heart development [GO:0007507]; muscle structure development [GO:0061061]; sarcomere organization [GO:0045214]	basal protein localization [GO:0045175]; cell adhesion [GO:0007155]; cellular response to tumor necrosis factor [GO:0071356]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165]	actin cytoskeleton organization [GO:0030036]; heart development [GO:0007507]; muscle structure development [GO:0061061]; sarcomere organization [GO:0045214]	basal plasma membrane [GO:0009925]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; glutamatergic synapse [GO:0098978]; hemidesmosome [GO:0030056]; nuclear membrane [GO:0031965]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	cell-cell adherens junction [GO:0005913]; cytoskeleton [GO:0005856]; filamentous actin [GO:0031941]; perinuclear region of cytoplasm [GO:0048471]; pseudopodium [GO:0031143]; stress fiber [GO:0001725]; Z disc [GO:0030018]	ErbB-2 class receptor binding [GO:0005176]; signaling receptor binding [GO:0005102]; structural constituent of cytoskeleton [GO:0005200]	actin binding [GO:0003779]; cytoskeletal protein binding [GO:0008092]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase C binding [GO:0005080]
d2h3pa1_d1b5sa___1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	glycolytic process [GO:0006096]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]		carnitine O-acetyltransferase activity [GO:0004092]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]
d2h3pa2_d1pd5g___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	response to antibiotic [GO:0046677]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]		carnitine O-acetyltransferase activity [GO:0004092]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d2h3pb2_d2h3ub1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	carnitine O-acetyltransferase activity [GO:0004092]	carnitine O-acetyltransferase activity [GO:0004092]
d2h3ua2_d2h4ta3__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	carnitine O-acetyltransferase activity [GO:0004092]	carnitine O-palmitoyltransferase activity [GO:0004095]
d2h3ub2_d1t7qa1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	carnitine O-acetyltransferase activity [GO:0004092]	carnitine O-acetyltransferase activity [GO:0004092]
d2h3ub2_d2ii4d___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]		endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	carnitine O-acetyltransferase activity [GO:0004092]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d2h3wa2_d3u9ff___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	response to antibiotic [GO:0046677]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]		carnitine O-acetyltransferase activity [GO:0004092]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d2h3wb2_d1q23b___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	response to antibiotic [GO:0046677]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]		carnitine O-acetyltransferase activity [GO:0004092]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d2h3xc__d1sfdb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; amine dehydrogenase activity [GO:0030058]; aralkylamine dehydrogenase (azurin) activity [GO:0030059]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	amine dehydrogenase activity [GO:0030058]; aralkylamine dehydrogenase (azurin) activity [GO:0030059]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2h3xf__d1tsac___1			Proteobacteria		periplasmic space [GO:0042597]; amine dehydrogenase activity [GO:0030058]; aralkylamine dehydrogenase (azurin) activity [GO:0030059]				periplasmic space [GO:0042597]		amine dehydrogenase activity [GO:0030058]; aralkylamine dehydrogenase (azurin) activity [GO:0030059]	
d2h3za__d1a6sa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]; aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral procapsid maturation [GO:0046797]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral procapsid maturation [GO:0046797]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d2h42a__d3sl8d___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d2h44a__d3n3za___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytosol [GO:0005829]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2h4cd__d1s8ga___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; inflammatory response [GO:0006954]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; inflammatory response [GO:0006954]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]
d2h4cg__d1bpqa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; inflammatory response [GO:0006954]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	arachidonic acid secretion [GO:0050482]; inflammatory response [GO:0006954]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; fatty acid biosynthetic process [GO:0006633]; innate immune response in mucosa [GO:0002227]; lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of fibroblast proliferation [GO:0048146]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]
d2h4ka__d1p15a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	integral component of synaptic membrane [GO:0099699]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]; protein tyrosine phosphatase activity [GO:0004725]; protein-containing complex binding [GO:0044877]; insulin receptor signaling pathway [GO:0008286]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of oligodendrocyte differentiation [GO:0048714]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	insulin receptor signaling pathway [GO:0008286]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of oligodendrocyte differentiation [GO:0048714]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	integral component of synaptic membrane [GO:0099699]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	protein-containing complex binding [GO:0044877]; protein tyrosine phosphatase activity [GO:0004725]
d2h4ta3_d2fw3a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	carnitine O-palmitoyltransferase activity [GO:0004095]	carnitine O-palmitoyltransferase activity [GO:0004095]
d2h4ua1_d1s5ue1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]; acyl-CoA hydrolase activity [GO:0047617]; acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]	plasma membrane [GO:0005886]; acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]; lipid metabolic process [GO:0006629]	acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]	lipid metabolic process [GO:0006629]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]	plasma membrane [GO:0005886]	acyl-CoA hydrolase activity [GO:0047617]	acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]
d2h4uc__d5eo2e___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]; acyl-CoA hydrolase activity [GO:0047617]; acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]		acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]		acyl-CoA hydrolase activity [GO:0047617]	
d2h4xa__d1yjxg___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]
d2h4za__d1v37b___1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	catalytic activity [GO:0003824]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]	catalytic activity [GO:0003824]
d2h4za__d5vveb1__1	Metazoa		Chordata	Heterolobosea	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]	phosphoglycerate mutase activity [GO:0004619]
d2h50f1_d4ylcb1__1	Viridiplantae		Streptophyta	Crenarchaeota	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]		protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2h50i1_d1shsf___1	Viridiplantae		Streptophyta	Euryarchaeota	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]
d2h50n1_d3w1zd___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to misfolded protein [GO:0071218]; cellular response to unfolded protein [GO:0034620]; chaperone-mediated protein folding [GO:0061077]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cellular response to heat [GO:0034605]; cellular response to misfolded protein [GO:0071218]; cellular response to unfolded protein [GO:0034620]; chaperone-mediated protein folding [GO:0061077]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]
d2h50o1_d1shse___1	Viridiplantae		Streptophyta	Euryarchaeota	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]
d2h50o1_d1wgva1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; unfolded protein binding [GO:0051082]; cilium assembly [GO:0060271]; developmental process [GO:0032502]; protein folding [GO:0006457]; protein localization to pericentriolar material [GO:1905793]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cilium assembly [GO:0060271]; developmental process [GO:0032502]; protein folding [GO:0006457]; protein localization to pericentriolar material [GO:1905793]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]	protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	unfolded protein binding [GO:0051082]
d2h50q1_d3aaba___1	Viridiplantae		Streptophyta	Crenarchaeota	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]		protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	
d2h50s1_d3aaca___1	Viridiplantae		Streptophyta	Crenarchaeota	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]		protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	
d2h52a__d2ekza___1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	catalytic activity [GO:0003824]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]	catalytic activity [GO:0003824]
d2h52b__d4pgmd___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]	phosphoglycerate mutase activity [GO:0004619]
d2h53a1_d4yl9c___1	Viridiplantae		Streptophyta	Crenarchaeota	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]		protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2h53b1_d3aabb___1	Viridiplantae		Streptophyta	Crenarchaeota	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]		protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	
d2h53c1_d4elda___1	Viridiplantae		Streptophyta	Euryarchaeota	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]
d2h53n1_d4ylba1__1	Viridiplantae		Streptophyta	Crenarchaeota	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]		protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2h53o1_d4ylcg1__1	Viridiplantae		Streptophyta	Crenarchaeota	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]		protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2h53q1_d3vqlb___1	Viridiplantae		Streptophyta	Crenarchaeota	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]		protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	
d2h53u1_d1ejfb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	chaperone complex [GO:0101031]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; telomerase holoenzyme complex [GO:0005697]; chaperone binding [GO:0051087]; DNA polymerase binding [GO:0070182]; Hsp90 protein binding [GO:0051879]; prostaglandin-E synthase activity [GO:0050220]; telomerase activity [GO:0003720]; unfolded protein binding [GO:0051082]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; cyclooxygenase pathway [GO:0019371]; positive regulation of phosphorylation [GO:0042327]; positive regulation of telomerase activity [GO:0051973]; prostaglandin biosynthetic process [GO:0001516]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]; xenobiotic metabolic process [GO:0006805]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; cyclooxygenase pathway [GO:0019371]; positive regulation of phosphorylation [GO:0042327]; positive regulation of telomerase activity [GO:0051973]; prostaglandin biosynthetic process [GO:0001516]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	chaperone complex [GO:0101031]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; telomerase holoenzyme complex [GO:0005697]	protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]	chaperone binding [GO:0051087]; DNA polymerase binding [GO:0070182]; Hsp90 protein binding [GO:0051879]; prostaglandin-E synthase activity [GO:0050220]; telomerase activity [GO:0003720]; unfolded protein binding [GO:0051082]
d2h59a__d2h2ia___1	Metazoa		Chordata	Thermotogae	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d2h59b__d4judx2__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	mandelate catabolic process [GO:0019596]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2h5lc1_d1psdb1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	L-serine biosynthetic process [GO:0006564]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	cytosol [GO:0005829]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]
d2h5lc1_d3hfga___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d2h5ua1_d5b7ea2__1	Fungi		Basidiomycota	Proteobacteria	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; oxidoreductase activity [GO:0016491]; lignin catabolic process [GO:0046274]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	lignin catabolic process [GO:0046274]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	extracellular region [GO:0005576]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; oxidoreductase activity [GO:0016491]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d2h5ya__d3h06e___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; molybdate ion binding [GO:0030973]; tungstate binding [GO:1901359]; molybdate ion transport [GO:0015689]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	molybdate ion transport [GO:0015689]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]; molybdate ion binding [GO:0030973]; tungstate binding [GO:1901359]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2h5yb__d4thia___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; molybdate ion binding [GO:0030973]; tungstate binding [GO:1901359]; molybdate ion transport [GO:0015689]	extracellular region [GO:0005576]; thiamine pyridinylase activity [GO:0050332]; thiamine catabolic process [GO:0009230]	molybdate ion transport [GO:0015689]	thiamine catabolic process [GO:0009230]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; molybdate ion binding [GO:0030973]; tungstate binding [GO:1901359]	thiamine pyridinylase activity [GO:0050332]
d2h5yc__d3rn8c___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; molybdate ion binding [GO:0030973]; tungstate binding [GO:1901359]; molybdate ion transport [GO:0015689]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	molybdate ion transport [GO:0015689]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]	metal ion binding [GO:0046872]; molybdate ion binding [GO:0030973]; tungstate binding [GO:1901359]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2h5zb__d2cjla___1	Metazoa		Arthropoda	Actinobacteria	lysozyme activity [GO:0003796]; metabolic process [GO:0008152]	chitinase activity [GO:0004568]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]			lysozyme activity [GO:0003796]	chitinase activity [GO:0004568]; metal ion binding [GO:0046872]
d2h60a__d3i3jb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; membrane [GO:0016020]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SWI/SNF complex [GO:0016514]; androgen receptor binding [GO:0050681]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA polymerase binding [GO:0070182]; DNA-dependent ATPase activity [GO:0008094]; helicase activity [GO:0004386]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]; Tat protein binding [GO:0030957]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; ATP-dependent chromatin remodeling [GO:0043044]; beta-catenin-TCF complex assembly [GO:1904837]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of cell growth [GO:0030308]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; neural retina development [GO:0003407]; nucleosome disassembly [GO:0006337]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of glucose mediated signaling pathway [GO:1902661]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription by RNA polymerase II [GO:0006357]	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]; acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	ATP-dependent chromatin remodeling [GO:0043044]; beta-catenin-TCF complex assembly [GO:1904837]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of cell growth [GO:0030308]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; neural retina development [GO:0003407]; nucleosome disassembly [GO:0006337]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of glucose mediated signaling pathway [GO:1902661]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription by RNA polymerase II [GO:0006357]	animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	extracellular space [GO:0005615]; membrane [GO:0016020]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SWI/SNF complex [GO:0016514]	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]	androgen receptor binding [GO:0050681]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA polymerase binding [GO:0070182]; helicase activity [GO:0004386]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]; Tat protein binding [GO:0030957]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]	acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]
d2h61a__d1b47a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]
d2h61c__d1mwna___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d2h61d__d1bt6b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of plasma membrane [GO:0019897]; calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; membrane raft assembly [GO:0001765]; positive regulation of binding [GO:0051099]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; response to drug [GO:0042493]; vesicle budding from membrane [GO:0006900]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	membrane raft assembly [GO:0001765]; positive regulation of binding [GO:0051099]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; response to drug [GO:0042493]; vesicle budding from membrane [GO:0006900]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of plasma membrane [GO:0019897]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]
d2h61g__d3rlza___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d2h61h__d1wrlc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]
d2h66a__d3a2xe___1			Apicomplexa	Crenarchaeota	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	peroxiredoxin activity [GO:0051920]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2h66c1_d1ep7b___1		Viridiplantae	Apicomplexa	Chlorophyta	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	peroxiredoxin activity [GO:0051920]	protein disulfide oxidoreductase activity [GO:0015035]
d2h66e__d2p5qa___1		Viridiplantae	Apicomplexa	Streptophyta	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	glutathione peroxidase activity [GO:0004602]; metal ion binding [GO:0046872]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	response to oxidative stress [GO:0006979]	cell [GO:0005623]		peroxiredoxin activity [GO:0051920]	glutathione peroxidase activity [GO:0004602]; metal ion binding [GO:0046872]
d2h66f__d2v41b___1		Metazoa	Apicomplexa	Annelida	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	peroxiredoxin activity [GO:0051920]	peroxiredoxin activity [GO:0051920]
d2h66g__d3e3eb___1		Metazoa	Apicomplexa	Chordata	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	peroxiredoxin activity [GO:0051920]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d2h66g__d4nhzd1__1			Apicomplexa	Proteobacteria	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	transferase activity [GO:0016740]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]		peroxiredoxin activity [GO:0051920]	transferase activity [GO:0016740]
d2h66h__d2jzra___1			Apicomplexa	Proteobacteria	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; cell redox homeostasis [GO:0045454]; cellular protein modification process [GO:0006464]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular protein modification process [GO:0006464]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cell [GO:0005623]	cell [GO:0005623]	peroxiredoxin activity [GO:0051920]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]
d2h66i1_d1k0bc2__1		Fungi	Apicomplexa	Ascomycota	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell redox homeostasis [GO:0045454]	cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]	cell [GO:0005623]	cytoplasm [GO:0005737]	peroxiredoxin activity [GO:0051920]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]
d2h68b__d1yfqa1__1	Metazoa	Fungi	Chordata	Ascomycota	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	bub1-bub3 complex [GO:1990298]; condensed nuclear chromosome kinetochore [GO:0000778]; kinetochore [GO:0000776]; mitotic checkpoint complex [GO:0033597]; ubiquitin binding [GO:0043130]; mitotic DNA integrity checkpoint [GO:0044774]; mitotic spindle assembly checkpoint [GO:0007094]; positive regulation of protein autoubiquitination [GO:1902499]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	mitotic DNA integrity checkpoint [GO:0044774]; mitotic spindle assembly checkpoint [GO:0007094]; positive regulation of protein autoubiquitination [GO:1902499]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	bub1-bub3 complex [GO:1990298]; condensed nuclear chromosome kinetochore [GO:0000778]; kinetochore [GO:0000776]; mitotic checkpoint complex [GO:0033597]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]	ubiquitin binding [GO:0043130]
d2h6ba1_d3jsoa1__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]; transcription, DNA-templated [GO:0006351]	regulation of transcription, DNA-templated [GO:0006355]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]	DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2h6ca1_d2gzwa1__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d2h6ca2_d3roua1__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d2h6jh1_d4qzxe___1		Fungi	Actinobacteria	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2h6jj1_d4qwkm___1		Fungi	Actinobacteria	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2h6pa1_d2yeza2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	protein homodimerization activity [GO:0042803]
d2h6pb__d4qt5a1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2h6pb__d5xf1d2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	lysozyme activity [GO:0003796]
d2h6sa__d5ahcb___1	Fungi		Ascomycota		extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; aspartic-type endopeptidase activity [GO:0004190]; adhesion of symbiont to host [GO:0044406]; fungal-type cell wall organization [GO:0031505]; induction by symbiont of defense-related host calcium ion flux [GO:0052391]; nitrogen compound metabolic process [GO:0006807]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; protein metabolic process [GO:0019538]; proteolysis [GO:0006508]; signal peptide processing [GO:0006465]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	adhesion of symbiont to host [GO:0044406]; fungal-type cell wall organization [GO:0031505]; induction by symbiont of defense-related host calcium ion flux [GO:0052391]; nitrogen compound metabolic process [GO:0006807]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; protein metabolic process [GO:0019538]; proteolysis [GO:0006508]; signal peptide processing [GO:0006465]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2h6uc__d3iwud___1	Metazoa	Metazoa	Chordata	Chordata	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d2h6xa__d1tofa___1		Viridiplantae	Proteobacteria	Chlorophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	protein disulfide oxidoreductase activity [GO:0015035]
d2h6xa__d2yzhc1__1			Proteobacteria	Aquificae	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	thioredoxin peroxidase activity [GO:0008379]
d2h6xb__d5jcge1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; alkyl hydroperoxide reductase activity [GO:0008785]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	alkyl hydroperoxide reductase activity [GO:0008785]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d2h6za__d4f82a1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2h6zb__d5k2ib1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2h70a__d1zyna2__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	alkyl hydroperoxide reductase activity [GO:0008785]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; NAD binding [GO:0051287]; protein disulfide oxidoreductase activity [GO:0015035]
d2h70a__d4hu7a___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2h71a__d1zofh___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2h72b__d1nw2c___1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	protein disulfide oxidoreductase activity [GO:0015035]
d2h73a__d1sjia2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; Z disc [GO:0030018]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	calcium ion binding [GO:0005509]
d2h75a__d1zcpd___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2h75a__d4k2da___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; periplasmic space [GO:0042597]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	protein disulfide oxidoreductase activity [GO:0015035]
d2h75b__d1bq7d___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d2h7ca__d1cuba___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	cutinase activity [GO:0050525]
d2h7cc__d1k8qb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	lipid catabolic process [GO:0016042]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	triglyceride lipase activity [GO:0004806]
d2h7cf__d1qe8a___1	Metazoa		Chordata		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]		carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	
d2h7ia__d5k4qa1__1						coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]						coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]
d2h7la__d4qsmh1__1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]		cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2h7la__d5b4ua___1				Proteobacteria		3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]						3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]
d2h80a1_d2dkya1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; lipid droplet [GO:0005811]; mitochondrial membrane [GO:0031966]; GTPase activator activity [GO:0005096]; lipid binding [GO:0008289]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	caveola [GO:0005901]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; GTPase activator activity [GO:0005096]; lipid binding [GO:0008289]; SH2 domain binding [GO:0042169]; actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; mitochondrial membrane [GO:0031966]	caveola [GO:0005901]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]	GTPase activator activity [GO:0005096]; lipid binding [GO:0008289]	GTPase activator activity [GO:0005096]; lipid binding [GO:0008289]; SH2 domain binding [GO:0042169]
d2h84a2_d2vb9c2__1				Proteobacteria	naringenin-chalcone synthase activity [GO:0016210]; oxidoreductase activity [GO:0016491]; aggregation involved in sorocarp development [GO:0031152]; chemotaxis to cAMP [GO:0043327]; flavonoid biosynthetic process [GO:0009813]; negative regulation of gene expression [GO:0010629]; polyketide biosynthetic process [GO:0030639]; positive regulation of gene expression [GO:0010628]; regulation of cAMP-mediated signaling [GO:0043949]; resorcinol metabolic process [GO:0019505]; signal transduction [GO:0007165]; sorocarp sorus development [GO:0048837]; sorocarp spore cell differentiation [GO:0044671]; sorocarp stalk cell differentiation [GO:0031149]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	aggregation involved in sorocarp development [GO:0031152]; chemotaxis to cAMP [GO:0043327]; flavonoid biosynthetic process [GO:0009813]; negative regulation of gene expression [GO:0010629]; polyketide biosynthetic process [GO:0030639]; positive regulation of gene expression [GO:0010628]; regulation of cAMP-mediated signaling [GO:0043949]; resorcinol metabolic process [GO:0019505]; signal transduction [GO:0007165]; sorocarp sorus development [GO:0048837]; sorocarp spore cell differentiation [GO:0044671]; sorocarp stalk cell differentiation [GO:0031149]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	naringenin-chalcone synthase activity [GO:0016210]; oxidoreductase activity [GO:0016491]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2h84a2_d2wkvb2__1				Proteobacteria	naringenin-chalcone synthase activity [GO:0016210]; oxidoreductase activity [GO:0016491]; aggregation involved in sorocarp development [GO:0031152]; chemotaxis to cAMP [GO:0043327]; flavonoid biosynthetic process [GO:0009813]; negative regulation of gene expression [GO:0010629]; polyketide biosynthetic process [GO:0030639]; positive regulation of gene expression [GO:0010628]; regulation of cAMP-mediated signaling [GO:0043949]; resorcinol metabolic process [GO:0019505]; signal transduction [GO:0007165]; sorocarp sorus development [GO:0048837]; sorocarp spore cell differentiation [GO:0044671]; sorocarp stalk cell differentiation [GO:0031149]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	aggregation involved in sorocarp development [GO:0031152]; chemotaxis to cAMP [GO:0043327]; flavonoid biosynthetic process [GO:0009813]; negative regulation of gene expression [GO:0010629]; polyketide biosynthetic process [GO:0030639]; positive regulation of gene expression [GO:0010628]; regulation of cAMP-mediated signaling [GO:0043949]; resorcinol metabolic process [GO:0019505]; signal transduction [GO:0007165]; sorocarp sorus development [GO:0048837]; sorocarp spore cell differentiation [GO:0044671]; sorocarp stalk cell differentiation [GO:0031149]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	naringenin-chalcone synthase activity [GO:0016210]; oxidoreductase activity [GO:0016491]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2h85a2_d2rhbc2__1					cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2h88b1_d5h57a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; etioplast stroma [GO:0009578]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; electron transport chain [GO:0022900]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; etioplast stroma [GO:0009578]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2h88b2_d4ytnf2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d2h89b2_d1gt8d1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d2h89b2_d3aefb2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d2h8da__d2uulu___1	Metazoa		Chordata		hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2h8db__d5v3ua___1	Metazoa		Chordata	Firmicutes	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen transport [GO:0015671]		oxygen transport [GO:0015671]	hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d2h8dc__d4h0mg___1	Metazoa		Chordata	Cyanobacteria	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2h8fd__d4wjgk___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2h8ga__d1rxug___1	Viridiplantae		Streptophyta	Proteobacteria	cytosol [GO:0005829]; plasma membrane [GO:0005886]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]
d2h8za__d3w2ja___1			Proteobacteria		FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d2h92a__d3hu2e3__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; pyrimidine nucleotide metabolic process [GO:0006220]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	pyrimidine nucleotide metabolic process [GO:0006220]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	cytoplasm [GO:0005737]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d2h9dc__d5ts9a___1			Proteobacteria	Proteobacteria	carbon-oxygen lyase activity [GO:0016835]; chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]; chorismate metabolic process [GO:0046417]; pyochelin biosynthetic process [GO:0042864]; salicylic acid biosynthetic process [GO:0009697]	chorismate metabolic process [GO:0046417]	chorismate metabolic process [GO:0046417]; pyochelin biosynthetic process [GO:0042864]; salicylic acid biosynthetic process [GO:0009697]	chorismate metabolic process [GO:0046417]			carbon-oxygen lyase activity [GO:0016835]; chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]	
d2h9eh__d2zgca___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; membrane [GO:0016020]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cytolysis [GO:0019835]; innate immune response [GO:0045087]; T cell mediated cytotoxicity [GO:0001913]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytolysis [GO:0019835]; innate immune response [GO:0045087]; T cell mediated cytotoxicity [GO:0001913]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; membrane [GO:0016020]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2h9ga2_d5feha1__1	Metazoa		Chordata		cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]		cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]	
d2h9gb1_d3ilqd___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2h9gh1_d3o6fe2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]	
d2h9gl2_d3qfda2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2h9ha__d1tmb.1__1		Metazoa		Annelida	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	serine-type endopeptidase inhibitor activity [GO:0004867]
d2h9nc__d1peva1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	actomyosin, actin portion [GO:0042643]; cortical actin cytoskeleton [GO:0030864]; myofibril [GO:0030016]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin filament depolymerization [GO:0030042]; locomotion [GO:0040011]; muscle thin filament assembly [GO:0071689]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of actin filament depolymerization [GO:0030836]; regulation of locomotion [GO:0040012]; sarcomere organization [GO:0045214]; skeletal muscle thin filament assembly [GO:0030240]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	actin filament depolymerization [GO:0030042]; locomotion [GO:0040011]; muscle thin filament assembly [GO:0071689]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of actin filament depolymerization [GO:0030836]; regulation of locomotion [GO:0040012]; sarcomere organization [GO:0045214]; skeletal muscle thin filament assembly [GO:0030240]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	actomyosin, actin portion [GO:0042643]; cortical actin cytoskeleton [GO:0030864]; myofibril [GO:0030016]; sarcoplasm [GO:0016528]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]	actin binding [GO:0003779]; actin filament binding [GO:0051015]
d2hada__d5uxzb1__1			Proteobacteria	Actinobacteria	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	response to toxic substance [GO:0009636]			haloalkane dehalogenase activity [GO:0018786]	haloalkane dehalogenase activity [GO:0018786]
d2haea2_d1nr7f2__1		Metazoa	Thermotogae	Chordata	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d2haea2_d3aogl1__1			Thermotogae	Deinococcus-Thermus	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]			malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d2haeb2_d1l1fe2__1		Metazoa	Thermotogae	Chordata	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]
d2haec2_d1nqtc2__1		Metazoa	Thermotogae	Chordata	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d2haec2_d4bhte1__1			Thermotogae	Proteobacteria	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]		glutamate biosynthetic process [GO:0006537]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]
d2haed2_d1nqtj2__1		Metazoa	Thermotogae	Chordata	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d2haha__d2r5qa___1					aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2hava1_d2abha___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	phosphate ion binding [GO:0042301]
d2havb1_d3t9xd___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2hb4a__d1g2kb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2hbca__d3b75f___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2hbda__d1kr7a___1	Metazoa	Metazoa	Chordata	Nemertea (ribbon worms)	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2hbfa__d1dlwa___1	Metazoa		Chordata	Ciliophora	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2hbga__d2vmlk___1	Metazoa		Annelida	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2hbia__d3p5qb___1		Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2hbib__d2qrwf___1				Actinobacteria		cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d2hbja1_d2dgza1__1	Fungi	Metazoa	Ascomycota	Chordata	nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleus [GO:0005634]; 3'-5'-exoribonuclease activity [GO:0000175]; nucleotide binding [GO:0000166]; single-stranded RNA binding [GO:0003727]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; histone mRNA catabolic process [GO:0071044]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent antisense transcript catabolic process [GO:0071040]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent snoRNA catabolic process [GO:0071036]; nuclear polyadenylation-dependent snRNA catabolic process [GO:0071037]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	centrosome [GO:0005813]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; replication fork [GO:0005657]; 3'-5' DNA helicase activity [GO:0043138]; 3'-5' exonuclease activity [GO:0008408]; 3'-flap-structured DNA binding [GO:0070337]; 8-hydroxy-2'-deoxyguanosine DNA binding [GO:1905773]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; bubble DNA binding [GO:0000405]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; exonuclease activity [GO:0004527]; forked DNA-dependent helicase activity [GO:0061749]; four-way junction DNA binding [GO:0000400]; four-way junction helicase activity [GO:0009378]; G-quadruplex DNA binding [GO:0051880]; helicase activity [GO:0004386]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; MutLalpha complex binding [GO:0032405]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; telomeric D-loop binding [GO:0061821]; telomeric G-quadruplex DNA binding [GO:0061849]; Y-form DNA binding [GO:0000403]; aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of strand invasion [GO:0098530]; protein localization to nucleolus [GO:1902570]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; regulation of signal transduction by p53 class mediator [GO:1901796]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomeric D-loop disassembly [GO:0061820]	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; histone mRNA catabolic process [GO:0071044]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent antisense transcript catabolic process [GO:0071040]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent snoRNA catabolic process [GO:0071036]; nuclear polyadenylation-dependent snRNA catabolic process [GO:0071037]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of strand invasion [GO:0098530]; protein localization to nucleolus [GO:1902570]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; regulation of signal transduction by p53 class mediator [GO:1901796]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomeric D-loop disassembly [GO:0061820]	nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleus [GO:0005634]	centrosome [GO:0005813]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; replication fork [GO:0005657]	3'-5'-exoribonuclease activity [GO:0000175]; nucleotide binding [GO:0000166]; single-stranded RNA binding [GO:0003727]	3'-5' DNA helicase activity [GO:0043138]; 3'-5' exonuclease activity [GO:0008408]; 3'-flap-structured DNA binding [GO:0070337]; 8-hydroxy-2'-deoxyguanosine DNA binding [GO:1905773]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; exonuclease activity [GO:0004527]; forked DNA-dependent helicase activity [GO:0061749]; four-way junction DNA binding [GO:0000400]; four-way junction helicase activity [GO:0009378]; G-quadruplex DNA binding [GO:0051880]; helicase activity [GO:0004386]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; MutLalpha complex binding [GO:0032405]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; telomeric D-loop binding [GO:0061821]; telomeric G-quadruplex DNA binding [GO:0061849]; Y-form DNA binding [GO:0000403]
d2hbma1_d2c35e___1	Fungi	Metazoa	Ascomycota	Chordata	nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleus [GO:0005634]; 3'-5'-exoribonuclease activity [GO:0000175]; nucleotide binding [GO:0000166]; single-stranded RNA binding [GO:0003727]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; histone mRNA catabolic process [GO:0071044]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent antisense transcript catabolic process [GO:0071040]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent snoRNA catabolic process [GO:0071036]; nuclear polyadenylation-dependent snRNA catabolic process [GO:0071037]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; RNA polymerase II, core complex [GO:0005665]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; translation initiation factor binding [GO:0031369]; 7-methylguanosine mRNA capping [GO:0006370]; apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral transcription [GO:0050434]; regulation of gene silencing by miRNA [GO:0060964]; RNA metabolic process [GO:0016070]; snRNA transcription by RNA polymerase II [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]; transcription-coupled nucleotide-excision repair [GO:0006283]	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; histone mRNA catabolic process [GO:0071044]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent antisense transcript catabolic process [GO:0071040]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent snoRNA catabolic process [GO:0071036]; nuclear polyadenylation-dependent snRNA catabolic process [GO:0071037]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	7-methylguanosine mRNA capping [GO:0006370]; apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral transcription [GO:0050434]; regulation of gene silencing by miRNA [GO:0060964]; RNA metabolic process [GO:0016070]; snRNA transcription by RNA polymerase II [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; transcription by RNA polymerase II [GO:0006366]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; RNA polymerase II, core complex [GO:0005665]	3'-5'-exoribonuclease activity [GO:0000175]; nucleotide binding [GO:0000166]; single-stranded RNA binding [GO:0003727]	DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; translation initiation factor binding [GO:0031369]
d2hbsd__d1j40b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2hbsg__d1i7ya___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2hbva1_d4lefe___1			Proteobacteria	Proteobacteria	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; zinc ion binding [GO:0008270]; catabolic process [GO:0009056]		catabolic process [GO:0009056]			carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; zinc ion binding [GO:0008270]
d2hbvb__d2i9ub2__1			Proteobacteria	Firmicutes	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	guanine deaminase activity [GO:0008892]; zinc ion binding [GO:0008270]; guanine catabolic process [GO:0006147]		guanine catabolic process [GO:0006147]			carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	guanine deaminase activity [GO:0008892]; zinc ion binding [GO:0008270]
d2hc0a__d1c70a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2hc0a__d5p6sa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2hc6a__d1exja2__1				Firmicutes		DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]		regulation of transcription, DNA-templated [GO:0006355]				DNA binding [GO:0003677]
d2hcbc2_d5awfd___1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; identical protein binding [GO:0042802]; DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; regulation of DNA replication [GO:0006275]	iron-sulfur cluster assembly [GO:0016226]; response to oxidative stress [GO:0006979]	DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; regulation of DNA replication [GO:0006275]	iron-sulfur cluster assembly [GO:0016226]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; identical protein binding [GO:0042802]	
d2hcka2_d5mo4a2__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]
d2hcma1_d3sr9a2__1	Metazoa	Metazoa	Chordata	Chordata	phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dephosphorylation [GO:0016311]	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; spinal cord development [GO:0021510]; synapse organization [GO:0050808]; synaptic membrane adhesion [GO:0099560]	dephosphorylation [GO:0016311]	cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; spinal cord development [GO:0021510]; synapse organization [GO:0050808]; synaptic membrane adhesion [GO:0099560]		axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]
d2hcoa__d1yied___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2hcra1_d1zn8b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]; adenine binding [GO:0002055]; adenine phosphoribosyltransferase activity [GO:0003999]; AMP binding [GO:0016208]; adenine salvage [GO:0006168]; AMP salvage [GO:0044209]; cellular response to insulin stimulus [GO:0032869]; grooming behavior [GO:0007625]; lactation [GO:0007595]; neutrophil degranulation [GO:0043312]; purine ribonucleoside salvage [GO:0006166]; purine-containing compound salvage [GO:0043101]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	adenine salvage [GO:0006168]; AMP salvage [GO:0044209]; cellular response to insulin stimulus [GO:0032869]; grooming behavior [GO:0007625]; lactation [GO:0007595]; neutrophil degranulation [GO:0043312]; purine-containing compound salvage [GO:0043101]; purine ribonucleoside salvage [GO:0006166]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]	adenine binding [GO:0002055]; adenine phosphoribosyltransferase activity [GO:0003999]; AMP binding [GO:0016208]
d2hczx2_d1whoa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; cell wall organization [GO:0071555]; sexual reproduction [GO:0019953]	extracellular region [GO:0005576]	cell wall organization [GO:0071555]; sexual reproduction [GO:0019953]		cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]		
d2hd1b__d4c1ib___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d2hd6a__d4wupa___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]
d2hd6a__d5fl5a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2hd7a1_d2fghb3__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; filopodium [GO:0030175]; myofibril [GO:0030016]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; actin filament depolymerization [GO:0030042]; barbed-end actin filament capping [GO:0051016]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of neuron projection development [GO:0010976]; regulation of actin phosphorylation [GO:0043538]; regulation of lamellipodium assembly [GO:0010591]; sequestering of actin monomers [GO:0042989]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament depolymerization [GO:0030042]; barbed-end actin filament capping [GO:0051016]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of neuron projection development [GO:0010976]; regulation of actin phosphorylation [GO:0043538]; regulation of lamellipodium assembly [GO:0010591]; sequestering of actin monomers [GO:0042989]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; filopodium [GO:0030175]; myofibril [GO:0030016]; perinuclear region of cytoplasm [GO:0048471]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d2hdba1_d3ho2a2__1			Firmicutes	Proteobacteria	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]		cytosol [GO:0005829]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d2hdbb1_d1h4fb1__1			Firmicutes	Proteobacteria	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2he0b1_d4hb5b1__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transmembrane signaling receptor activity [GO:0004888]; animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral genome replication [GO:0045070]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; regulation of transcription, DNA-templated [GO:0006355]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]		animal organ regeneration [GO:0031100]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell cycle arrest [GO:0007050]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium assembly [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary sinus valve morphogenesis [GO:0003182]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; homeostasis of number of cells within a tissue [GO:0048873]; humoral immune response [GO:0006959]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; in utero embryonic development [GO:0001701]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell proliferation involved in heart valve morphogenesis [GO:0003252]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of extracellular matrix constituent secretion [GO:0003332]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of growth rate [GO:0045967]; negative regulation of inner ear auditory receptor cell differentiation [GO:0045608]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; outflow tract morphogenesis [GO:0003151]; pericardium morphogenesis [GO:0003344]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of apoptotic process involved in morphogenesis [GO:1902339]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; MAML1-RBP-Jkappa- ICN1 complex [GO:0002193]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; Notch binding [GO:0005112]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transmembrane signaling receptor activity [GO:0004888]	
d2he3a1_d4l0ui1__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; electron transfer activity [GO:0009055]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	electron transfer activity [GO:0009055]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]	peroxiredoxin activity [GO:0051920]
d2he3a1_d5g30c___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; electron transfer activity [GO:0009055]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	electron transfer activity [GO:0009055]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]	protein disulfide oxidoreductase activity [GO:0015035]
d2he4a1_d2l4ta___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]; protein-containing complex assembly [GO:0065003]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]; activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	protein-containing complex assembly [GO:0065003]	activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	apical plasma membrane [GO:0016324]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]	beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]	beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]
d2he5a__d3d3fb___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	methylglyoxal reductase (NADPH-dependent) activity [GO:0043892]	oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]		cytosol [GO:0005829]		17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]	methylglyoxal reductase (NADPH-dependent) activity [GO:0043892]
d2he5b__d1j96b1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]	cytosol [GO:0005829]	17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]
d2he7a2_d4zria2__1	Metazoa	Metazoa	Chordata	Chordata	axolemma [GO:0030673]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; juxtaparanode region of axon [GO:0044224]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; actin binding [GO:0003779]; structural constituent of cytoskeleton [GO:0005200]; actomyosin structure organization [GO:0031032]; apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; cytoskeletal anchoring at plasma membrane [GO:0007016]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actomyosin structure organization [GO:0031032]; apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; cytoskeletal anchoring at plasma membrane [GO:0007016]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360]	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	axolemma [GO:0030673]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; juxtaparanode region of axon [GO:0044224]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	actin binding [GO:0003779]; structural constituent of cytoskeleton [GO:0005200]	actin binding [GO:0003779]
d2he8b__d1z9ac___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	oxidoreductase activity [GO:0016491]; D-xylose catabolic process [GO:0042843]	oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	D-xylose catabolic process [GO:0042843]	cytosol [GO:0005829]		17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]	oxidoreductase activity [GO:0016491]
d2heaa__d2zija___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2heba__d2ybja___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2heca__d4owca___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2hejb__d2ipga___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]	cytosol [GO:0005829]	17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]	17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]
d2hera__d5cg5a___1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]		cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]		dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2heta__d1a4pb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; calcium ion binding [GO:0005509]; phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of plasma membrane [GO:0019897]; calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; membrane raft assembly [GO:0001765]; positive regulation of binding [GO:0051099]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; response to drug [GO:0042493]; vesicle budding from membrane [GO:0006900]	phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	membrane raft assembly [GO:0001765]; positive regulation of binding [GO:0051099]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; response to drug [GO:0042493]; vesicle budding from membrane [GO:0006900]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of plasma membrane [GO:0019897]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]
d2hetb__d1y1aa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; calcium ion binding [GO:0005509]; phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; filopodium tip [GO:0032433]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; calcium-dependent protein kinase inhibitor activity [GO:0008427]; ion channel binding [GO:0044325]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein membrane anchor [GO:0043495]; protein serine/threonine kinase inhibitor activity [GO:0030291]; Ras GTPase binding [GO:0017016]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to growth factor stimulus [GO:0071363]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; cytoplasmic microtubule organization [GO:0031122]; double-strand break repair [GO:0006302]; endomitotic cell cycle [GO:0007113]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; platelet formation [GO:0030220]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of male germ cell proliferation [GO:2000256]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of cell division [GO:0051302]; regulation of cell population proliferation [GO:0042127]; response to ischemia [GO:0002931]; spermatid development [GO:0007286]; thrombopoietin-mediated signaling pathway [GO:0038163]	phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to growth factor stimulus [GO:0071363]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; cytoplasmic microtubule organization [GO:0031122]; double-strand break repair [GO:0006302]; endomitotic cell cycle [GO:0007113]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; platelet formation [GO:0030220]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of male germ cell proliferation [GO:2000256]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of cell division [GO:0051302]; regulation of cell population proliferation [GO:0042127]; response to ischemia [GO:0002931]; spermatid development [GO:0007286]; thrombopoietin-mediated signaling pathway [GO:0038163]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; filopodium tip [GO:0032433]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]	calcium-dependent protein kinase inhibitor activity [GO:0008427]; calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein membrane anchor [GO:0043495]; protein serine/threonine kinase inhibitor activity [GO:0030291]; Ras GTPase binding [GO:0017016]
d2heyf__d1pk6c___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; tumor necrosis factor-activated receptor activity [GO:0005031]; virus receptor activity [GO:0001618]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of immunoglobulin secretion [GO:0051024]; T cell proliferation [GO:0042098]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	blood microparticle [GO:0072562]; cell [GO:0005623]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; postsynapse [GO:0098794]; synapse [GO:0045202]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; regulation of complement activation [GO:0030449]; synapse pruning [GO:0098883]	immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of immunoglobulin secretion [GO:0051024]; T cell proliferation [GO:0042098]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; regulation of complement activation [GO:0030449]; synapse pruning [GO:0098883]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; postsynapse [GO:0098794]; synapse [GO:0045202]	tumor necrosis factor-activated receptor activity [GO:0005031]; virus receptor activity [GO:0001618]	
d2heyg__d5h48a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; tumor necrosis factor-activated receptor activity [GO:0005031]; virus receptor activity [GO:0001618]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of immunoglobulin secretion [GO:0051024]; T cell proliferation [GO:0042098]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic membrane [GO:0045211]; synaptic cleft [GO:0043083]; protein homodimerization activity [GO:0042803]; cerebellar granule cell differentiation [GO:0021707]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of excitatory postsynaptic potential [GO:0090394]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; protein secretion [GO:0009306]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]	immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of immunoglobulin secretion [GO:0051024]; T cell proliferation [GO:0042098]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cerebellar granule cell differentiation [GO:0021707]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of excitatory postsynaptic potential [GO:0090394]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; protein secretion [GO:0009306]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic membrane [GO:0045211]; synaptic cleft [GO:0043083]	tumor necrosis factor-activated receptor activity [GO:0005031]; virus receptor activity [GO:0001618]	protein homodimerization activity [GO:0042803]
d2hf4a2_d3l4ia1__1	Metazoa		Arthropoda	Apicomplexa	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	ATP binding [GO:0005524]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]		actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]		ATP binding [GO:0005524]	ATP binding [GO:0005524]
d2hf4a2_d4k42c2__1	Metazoa	Metazoa	Arthropoda	Chordata	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2hf7a__d2g80b___1		Fungi	Proteobacteria	Ascomycota	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity [GO:0043715]; 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity [GO:0043716]; acireductone synthase activity [GO:0043874]; magnesium ion binding [GO:0000287]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]		L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]	outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity [GO:0043715]; 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity [GO:0043716]; acireductone synthase activity [GO:0043874]; magnesium ion binding [GO:0000287]
d2hf7b__d1rdfa___1			Proteobacteria	Firmicutes	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]		organic phosphonate catabolic process [GO:0019700]	outer membrane-bounded periplasmic space [GO:0030288]		acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]
d2hfda1_d3sbcb1__1		Fungi	Proteobacteria	Ascomycota	signal sequence binding [GO:0005048]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]; identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]; cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]		cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]	signal sequence binding [GO:0005048]	identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]
d2hffl1_d3rvuc1__1												
d2hffl1_d4weud___1		Metazoa		Chordata								
d2hfgh1_d1py4c___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2hfgl1_d1rihh1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2hfgl2_d4x6ch1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; B cell costimulation [GO:0031296]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of T cell proliferation [GO:0042102]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2hfha__d2lf7a1__1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; sequence-specific DNA binding [GO:0043565]; anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; in utero embryonic development [GO:0001701]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; vitellogenesis [GO:0007296]	anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; in utero embryonic development [GO:0001701]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]	cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; vitellogenesis [GO:0007296]	nucleus [GO:0005634]	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d2hfna__d1x0pi___1			Cyanobacteria	Cyanobacteria	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]
d2hfnb__d2w4da___1			Cyanobacteria	Euryarchaeota	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]
d2hfnb__d4ojgb___1			Cyanobacteria	Crenarchaeota	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]
d2hfnc__d2bjda___1			Cyanobacteria	Crenarchaeota	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]
d2hfne__d4yhva___1		Fungi	Cyanobacteria	Ascomycota	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]		spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	
d2hfnf__d2kb2a1__1			Cyanobacteria	Proteobacteria	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2hfng__d2bjeg___1			Cyanobacteria	Crenarchaeota	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]
d2hfob__d1x0pj___1			Cyanobacteria	Cyanobacteria	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]
d2hfoe__d2bycb2__1			Cyanobacteria		blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]						blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	
d2hfoe__d4ojhb___1			Cyanobacteria	Crenarchaeota	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]
d2hfof__d2iyga___1			Cyanobacteria	Proteobacteria	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]
d2hfog__d2acya___1		Metazoa	Cyanobacteria	Chordata	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]
d2hfoi__d2w4df___1			Cyanobacteria	Euryarchaeota	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]
d2hgik1_d1i97h___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2hgim1_d2aw7j1__1												
d2hgiv1_d1vs5s1__1												
d2hgiw1_d1yl4w1__1												
d2hgjd2_d2qoxc2__1												
d2hgje1_d2plfa1__1				Crenarchaeota		cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d2hgje1_d3ccqb1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2hgjr1_d1n34k___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2hgjt1_d2b66u1__1												
d2hgju1_d2qp1r1__1												
d2hgma__d3mxhp___1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; TBP-class protein binding [GO:0017025]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-12-mediated signaling pathway [GO:0035722]; mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-12-mediated signaling pathway [GO:0035722]; mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; TBP-class protein binding [GO:0017025]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]
d2hgpi1_d2avyf1__1												
d2hgpn1_d2qamo1__1												
d2hgpw1_d2qbft1__1												
d2hgqe1_d4iw3k2__1				Proteobacteria		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2hgqr1_d1vs6o1__1												
d2hgqx1_d1vq8t1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2hgrh2_d1h2id___1		Metazoa		Chordata		nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]		cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]		nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]		DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]
d2hgrm1_d2vhpj1__1												
d2hgu71_d2awb31__1												
d2hgud1_d1ffka1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2hgue1_d2j01e1__1												
d2hgue1_d2qmua1__1				Crenarchaeota		cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d2hgut1_d2qamq1__1												
d2hgux1_d2qovu1__1												
d2hgza1_d1woya2__1			Euryarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; methionyl-tRNA aminoacylation [GO:0006431]	tyrosyl-tRNA aminoacylation [GO:0006437]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]
d2hh0h1_d4pjhf1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homooligomerization [GO:0051260]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	protein homooligomerization [GO:0051260]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	anchored component of membrane [GO:0031225]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	copper ion binding [GO:0005507]; identical protein binding [GO:0042802]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2hh0h2_d4gxvl2__1	Metazoa		Chordata		anchored component of membrane [GO:0031225]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homooligomerization [GO:0051260]		protein homooligomerization [GO:0051260]		anchored component of membrane [GO:0031225]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; identical protein binding [GO:0042802]	
d2hh5b__d2aima___1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	cysteine-type endopeptidase activity [GO:0004197]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	cysteine-type endopeptidase activity [GO:0004197]
d2hhaa2_d4dyha___1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	triglyceride lipase activity [GO:0004806]
d2hhab2_d1xzka___1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	cutinase activity [GO:0050525]
d2hhea__d1mwdb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2hhea__d5nb4l___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2hhhg1_d2i2ug1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d2hhhi1_d1s16a1__1			Deinococcus-Thermus	Proteobacteria	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	chromosome [GO:0005694]; cytosol [GO:0005829]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; chromosome organization [GO:0051276]; DNA topological change [GO:0006265]; plasmid partitioning [GO:0030541]; response to antibiotic [GO:0046677]; sister chromatid cohesion [GO:0007062]	translation [GO:0006412]	chromosome organization [GO:0051276]; DNA topological change [GO:0006265]; plasmid partitioning [GO:0030541]; response to antibiotic [GO:0046677]; sister chromatid cohesion [GO:0007062]	ribosome [GO:0005840]	chromosome [GO:0005694]; cytosol [GO:0005829]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d2hhla__d3nrje1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein phosphorylation [GO:0001933]; regulation of transcription by RNA polymerase II [GO:0006357]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein phosphorylation [GO:0001933]; regulation of transcription by RNA polymerase II [GO:0006357]	lipopolysaccharide biosynthetic process [GO:0009103]	extracellular exosome [GO:0070062]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d2hhlc1_d3qu5b1__1	Metazoa		Chordata	Bacteroidetes	extracellular exosome [GO:0070062]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein phosphorylation [GO:0001933]; regulation of transcription by RNA polymerase II [GO:0006357]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein phosphorylation [GO:0001933]; regulation of transcription by RNA polymerase II [GO:0006357]		extracellular exosome [GO:0070062]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]
d2hhna__d1m6da___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; cysteine-type endopeptidase activity [GO:0004197]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	cysteine-type endopeptidase activity [GO:0004197]
d2hhpa1_d2zh8a1__1	Fungi		Ascomycota	Euryarchaeota	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]
d2hhpa2_d2pfna3__1	Fungi	Metazoa	Ascomycota	Chordata	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d2hhua1_d4dtoa1__1			Firmicutes		3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2hhwd1_d2jgua1__1			Firmicutes	Euryarchaeota	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; endonuclease activity [GO:0004519]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	DNA replication [GO:0006260]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; endonuclease activity [GO:0004519]; nucleotide binding [GO:0000166]
d2hi2a__d3g20a___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]; cell adhesion [GO:0007155]	type II protein secretion system complex [GO:0015627]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein secretion by the type II secretion system [GO:0015628]	cell adhesion [GO:0007155]	protein secretion by the type II secretion system [GO:0015628]	pilus [GO:0009289]	type II protein secretion system complex [GO:0015627]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2hiaa__d1riib___1			Deinococcus-Thermus	Actinobacteria	catalytic activity [GO:0003824]	plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; identical protein binding [GO:0042802]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]		plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	catalytic activity [GO:0003824]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; identical protein binding [GO:0042802]
d2hioa__d3mgpc___1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleosome [GO:0000786]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2hiod__d3aznd___1	Metazoa	Metazoa	Chordata	Chordata	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleosome [GO:0000786]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2hj2a2_d3tdea1__1				Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]		one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]
d2hj2b2_d4le5a1__1												
d2hj2b3_d5t8sb1__1				Proteobacteria		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]		one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]
d2hjdd__d1us6a___1			Proteobacteria	Proteobacteria	negative regulation of transcription, DNA-templated [GO:0045892]	conjugation [GO:0000746]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	conjugation [GO:0000746]; negative regulation of transcription, DNA-templated [GO:0045892]				
d2hjfa2_d2uzih___1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	voltage-gated potassium channel complex [GO:0008076]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d2hjfb1_d3cfkm1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	voltage-gated potassium channel complex [GO:0008076]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2hjfb1_d4ei5f___1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	voltage-gated potassium channel complex [GO:0008076]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2hjka1_d4ra0d2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; platelet alpha granule lumen [GO:0031093]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; phosphatidylserine binding [GO:0001786]; protein binding, bridging [GO:0030674]; protein tyrosine kinase activator activity [GO:0030296]; receptor ligand activity [GO:0048018]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; voltage-gated calcium channel activity [GO:0005245]; activation of protein kinase B activity [GO:0032148]; animal organ regeneration [GO:0031100]; apoptotic cell clearance [GO:0043277]; B cell chemotaxis [GO:0035754]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular protein metabolic process [GO:0044267]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to interferon-alpha [GO:0035457]; cellular response to starvation [GO:0009267]; cellular response to vitamin K [GO:0071307]; dendritic cell differentiation [GO:0097028]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; enzyme linked receptor protein signaling pathway [GO:0007167]; extracellular matrix assembly [GO:0085029]; fusion of virus membrane with host plasma membrane [GO:0019064]; hematopoietic stem cell migration to bone marrow [GO:0097241]; leukocyte migration [GO:0050900]; macrophage cytokine production [GO:0010934]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 secretion [GO:0050711]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of oligodendrocyte apoptotic process [GO:1900142]; negative regulation of renal albumin absorption [GO:2000533]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; neuron migration [GO:0001764]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerular filtration [GO:0003104]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of TOR signaling [GO:0032008]; post-translational protein modification [GO:0043687]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of growth [GO:0040008]; signal transduction [GO:0007165]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of protein kinase B activity [GO:0032148]; animal organ regeneration [GO:0031100]; apoptotic cell clearance [GO:0043277]; B cell chemotaxis [GO:0035754]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular protein metabolic process [GO:0044267]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to interferon-alpha [GO:0035457]; cellular response to starvation [GO:0009267]; cellular response to vitamin K [GO:0071307]; dendritic cell differentiation [GO:0097028]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; enzyme linked receptor protein signaling pathway [GO:0007167]; extracellular matrix assembly [GO:0085029]; fusion of virus membrane with host plasma membrane [GO:0019064]; hematopoietic stem cell migration to bone marrow [GO:0097241]; leukocyte migration [GO:0050900]; macrophage cytokine production [GO:0010934]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 secretion [GO:0050711]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of oligodendrocyte apoptotic process [GO:1900142]; negative regulation of renal albumin absorption [GO:2000533]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; neuron migration [GO:0001764]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerular filtration [GO:0003104]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of TOR signaling [GO:0032008]; post-translational protein modification [GO:0043687]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of growth [GO:0040008]; signal transduction [GO:0007165]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; platelet alpha granule lumen [GO:0031093]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; phosphatidylserine binding [GO:0001786]; protein binding, bridging [GO:0030674]; protein tyrosine kinase activator activity [GO:0030296]; receptor ligand activity [GO:0048018]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; voltage-gated calcium channel activity [GO:0005245]
d2hjkb__d2oldb2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2hjlb__d5jopd1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2hjra1_d1n9gc2__1		Fungi	Apicomplexa	Ascomycota	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		mitochondrion [GO:0005739]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]
d2hjra2_d2v65a2__1		Metazoa	Apicomplexa	Chordata	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		cytoplasm [GO:0005737]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	L-lactate dehydrogenase activity [GO:0004459]
d2hjrc1_d4kugb1__1			Apicomplexa	Firmicutes	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	fatty acid metabolic process [GO:0006631]			oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]
d2hjrd1_d5i7ea___1			Apicomplexa	Proteobacteria	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	fatty acid biosynthetic process [GO:0006633]			oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d2hjrf1_d1kewb___1			Apicomplexa	Proteobacteria	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; NADH binding [GO:0070404]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]			oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; NADH binding [GO:0070404]
d2hjrf1_d5ej2c___1			Apicomplexa	Actinobacteria	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	(+)-trans-carveol dehydrogenase activity [GO:0033702]; nucleotide binding [GO:0000166]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]				oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	(+)-trans-carveol dehydrogenase activity [GO:0033702]; nucleotide binding [GO:0000166]
d2hjrg1_d2x86e___1			Apicomplexa	Proteobacteria	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]			oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]
d2hjrj1_d5jfoc___1			Apicomplexa	Actinobacteria	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d2hjrj2_d1pzhc2__1			Apicomplexa	Apicomplexa	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]			oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d2hjrl1_d1jayb___1			Apicomplexa	Euryarchaeota	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity [GO:0102261]; coenzyme F420 binding [GO:0070967]; NADP binding [GO:0050661]; reduced coenzyme F420:NADP+ oxidoreductase activity [GO:0052808]; NADPH regeneration [GO:0006740]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	NADPH regeneration [GO:0006740]			oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity [GO:0102261]; coenzyme F420 binding [GO:0070967]; NADP binding [GO:0050661]; reduced coenzyme F420:NADP+ oxidoreductase activity [GO:0052808]
d2hjrl2_d2v6ma2__1			Apicomplexa	Deinococcus-Thermus	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	L-lactate dehydrogenase activity [GO:0004459]
d2hk7a1_d1p77a2__1			Aquificae	Proteobacteria	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]	cytosol [GO:0005829]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d2hk7a1_d5dzsb1__1			Aquificae	Firmicutes	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d2hk8a1_d3aogf1__1			Aquificae	Deinococcus-Thermus	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d2hk8a2_d4dwva2__1		Metazoa	Aquificae	Chordata	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]	cytosol [GO:0005829]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d2hk8d1_d3ngxa1__1			Aquificae	Euryarchaeota	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]
d2hk8d2_d1p1rb2__1		Metazoa	Aquificae	Chordata	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]	cytosol [GO:0005829]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d2hk8e1_d3eteb1__1		Metazoa	Aquificae	Chordata	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytosol [GO:0005829]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d2hk8e2_d1ib6b1__1			Aquificae	Proteobacteria	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]
d2hk8h2_d1bw9b1__1			Aquificae	Actinobacteria	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d2hk8h2_d1jaxa___1			Aquificae	Euryarchaeota	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity [GO:0102261]; coenzyme F420 binding [GO:0070967]; NADP binding [GO:0050661]; reduced coenzyme F420:NADP+ oxidoreductase activity [GO:0052808]; NADPH regeneration [GO:0006740]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	NADPH regeneration [GO:0006740]	cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity [GO:0102261]; coenzyme F420 binding [GO:0070967]; NADP binding [GO:0050661]; reduced coenzyme F420:NADP+ oxidoreductase activity [GO:0052808]
d2hk9a1_d3k92e1__1			Aquificae	Firmicutes	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	glutamate dehydrogenase (NAD+) activity [GO:0004352]
d2hkac__d3a6oa1__1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; lysosome [GO:0005764]; cholesterol binding [GO:0015485]; sterol binding [GO:0032934]; cholesterol efflux [GO:0033344]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; intracellular cholesterol transport [GO:0032367]; sterol transport [GO:0015918]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	cholesterol efflux [GO:0033344]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; intracellular cholesterol transport [GO:0032367]; sterol transport [GO:0015918]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; lysosome [GO:0005764]		cholesterol binding [GO:0015485]; sterol binding [GO:0032934]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2hkhl2_d3o2wl1__1	Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		antigen binding [GO:0003823]	
d2hkia2_d1p9la2__1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	chloroplast [GO:0009507]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]
d2hkja3_d1b62a2__1			Crenarchaeota	Proteobacteria	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	mismatch repair complex [GO:0032300]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]		mismatch repair complex [GO:0032300]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]
d2hl0a__d4rrfe___1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; threonyl-tRNA aminoacylation [GO:0006435]	mitochondrion [GO:0005739]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; threonyl-tRNA aminoacylation [GO:0006435]	threonyl-tRNA aminoacylation [GO:0006435]	threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]	mitochondrion [GO:0005739]	ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2hl2a__d4rrja___1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; threonyl-tRNA aminoacylation [GO:0006435]	threonyl-tRNA aminoacylation [GO:0006435]	threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2hl5d__d3e2ub___1	Metazoa	Metazoa	Chordata	Chordata	cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; cell division [GO:0051301]; cell migration [GO:0016477]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of cell migration [GO:0030335]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; intermediate filament [GO:0005882]; kinetochore [GO:0000776]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nuclear envelope [GO:0005635]; ruffle [GO:0001726]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116]; protein transport into plasma membrane raft [GO:0044861]	cell division [GO:0051301]; cell migration [GO:0016477]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of cell migration [GO:0030335]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116]; protein transport into plasma membrane raft [GO:0044861]	cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]	centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; intermediate filament [GO:0005882]; kinetochore [GO:0000776]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nuclear envelope [GO:0005635]; ruffle [GO:0001726]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270]
d2hl6b__d4glba___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]; cell wall macromolecule catabolic process [GO:0016998]; cellulose catabolic process [GO:0030245]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cellulose catabolic process [GO:0030245]; cell wall macromolecule catabolic process [GO:0016998]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]		cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]	triglyceride lipase activity [GO:0004806]
d2hlaa1_d2eyra1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2hlaa2_d1s7ra2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2hlaa2_d4nqea1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2hlca__d1ejna___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	collagen catabolic process [GO:0030574]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular region [GO:0005576]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d2hlca__d1sgta___1	Metazoa		Arthropoda	Actinobacteria	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]	serine-type endopeptidase activity [GO:0004252]	collagen catabolic process [GO:0030574]		extracellular region [GO:0005576]		serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d2hlcb__d3sjod___1	Metazoa		Arthropoda		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	collagen catabolic process [GO:0030574]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2hlda1_d3vr6f1__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]		hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldb1_d5kncf1__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]		hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldc2_d2ck3f3__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldd1_d4yxwa1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldf2_d1w0je3__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldf3_d3gqbd3__1	Fungi		Ascomycota	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]		hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldj1_d2qe7f1__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldj1_d3oe7n1__1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldl1_d3a5cl1__1	Fungi		Ascomycota	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]		hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldl2_d3uiea___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	chloroplast [GO:0009507]; plastid [GO:0009536]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; phosphorylation [GO:0016310]; sulfate assimilation [GO:0000103]	ATP synthesis coupled proton transport [GO:0015986]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; phosphorylation [GO:0016310]; sulfate assimilation [GO:0000103]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	chloroplast [GO:0009507]; plastid [GO:0009536]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]
d2hldm3_d3a5cf3__1	Fungi		Ascomycota	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]		hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldn2_d2jj1c2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldo1_d5hkkb1__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldo3_d1h8ed1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldo3_d5ik2d3__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hlds2_d3oehm2__1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hldw1_d2jdia2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2hlff2_d5w1wt1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2hlpa2_d3pqdc2__1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d2hlsb1_d5a5kc1__1		Viridiplantae	Crenarchaeota	Streptophyta		apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]		camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d2hlta__d1x0pe___1			Firmicutes	Cyanobacteria	acylphosphatase activity [GO:0003998]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]					acylphosphatase activity [GO:0003998]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]
d2hlta__d2hfne___1			Firmicutes	Cyanobacteria	acylphosphatase activity [GO:0003998]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]					acylphosphatase activity [GO:0003998]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]
d2hlua__d1x0pb___1			Firmicutes	Cyanobacteria	acylphosphatase activity [GO:0003998]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]					acylphosphatase activity [GO:0003998]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]
d2hm2q__d1a1wa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; IkappaB kinase complex [GO:0008385]; nucleus [GO:0005634]; cysteine-type endopeptidase activity [GO:0004197]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; positive regulation of interleukin-1 beta secretion [GO:0050718]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; positive regulation of interleukin-1 beta secretion [GO:0050718]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	cytosol [GO:0005829]; IkappaB kinase complex [GO:0008385]; nucleus [GO:0005634]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	cysteine-type endopeptidase activity [GO:0004197]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]
d2hm7a__d3fvrb___1			Firmicutes	Firmicutes	hydrolase activity [GO:0016787]	acetylesterase activity [GO:0008126]					hydrolase activity [GO:0016787]	acetylesterase activity [GO:0008126]
d2hm9a__d1rx3a___1			Firmicutes	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d2hm9a__d3jwma1__1			Firmicutes	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d2hmfd2_d2bj1a2__1			Euryarchaeota	Euryarchaeota	cytosol [GO:0005829]; aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]; homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nickel cation binding [GO:0016151]; response to nickel cation [GO:0010045]	homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	response to nickel cation [GO:0010045]	cytosol [GO:0005829]		aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nickel cation binding [GO:0016151]
d2hmge__d5t6se___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d2hmic1_d3mckl1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d2hmic2_d1dqqc1__1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2hmic2_d1rzie2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d2hmja1_d1z02a1__1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	aromatic compound catabolic process [GO:0019439]				dioxygenase activity [GO:0051213]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d2hmja2_d4n3eo___1		Viridiplantae	Proteobacteria	Streptophyta	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]			dioxygenase activity [GO:0051213]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2hmka2_d5xbpd2__1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]			dioxygenase activity [GO:0051213]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]
d2hmkb__d2b1xd___1			Proteobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]			dioxygenase activity [GO:0051213]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]
d2hmla1_d1z01e1__1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	aromatic compound catabolic process [GO:0019439]				dioxygenase activity [GO:0051213]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d2hmla1_d3l70e2__1		Metazoa	Proteobacteria	Chordata	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	aromatic compound catabolic process [GO:0019439]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	dioxygenase activity [GO:0051213]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d2hmla2_d4gy9a1__1		Viridiplantae	Proteobacteria	Streptophyta	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; cytokinin-activated signaling pathway [GO:0009736]; defense response [GO:0006952]; nodulation [GO:0009877]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; cytokinin-activated signaling pathway [GO:0009736]; defense response [GO:0006952]; nodulation [GO:0009877]; response to biotic stimulus [GO:0009607]			dioxygenase activity [GO:0051213]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2hmma2_d1btva___1		Viridiplantae	Proteobacteria	Streptophyta	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]	dioxygenase activity [GO:0051213]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2hmmb__d2xr8n___1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			dioxygenase activity [GO:0051213]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2hmna1_d1uljc1__1			Proteobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			dioxygenase activity [GO:0051213]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2hmna2_d4ma6a___1		Viridiplantae	Proteobacteria	Streptophyta	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]			dioxygenase activity [GO:0051213]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2hmob__d2ckfb___1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]			dioxygenase activity [GO:0051213]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]
d2hmsb__d4l75a1__1			Firmicutes	Euryarchaeota	plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; potassium ion transport [GO:0006813]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2hmua__d5h5xg___1			Firmicutes	Actinobacteria	plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; potassium ion transport [GO:0006813]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	potassium ion transport [GO:0006813]		plasma membrane [GO:0005886]		cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2hmub__d4pzeb1__1			Firmicutes	Proteobacteria	plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; potassium ion transport [GO:0006813]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	potassium ion transport [GO:0006813]	fatty acid metabolic process [GO:0006631]	plasma membrane [GO:0005886]		cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d2hmva__d1bvrd___1			Firmicutes	Actinobacteria	plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; potassium ion transport [GO:0006813]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	potassium ion transport [GO:0006813]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	plasma membrane [GO:0005886]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d2hmxa__d1jvra___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	viral nucleocapsid [GO:0019013]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2hmzb__d1i4yd___1	Metazoa	Metazoa	Annelida	Annelida	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]					iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]
d2hn7a2_d4lcwa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2hn7b__d5wk2l2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2hnba__d3tzba1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; FMN binding [GO:0010181]; oxidation-reduction process [GO:0055114]; regulation of cell division [GO:0051302]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]; regulation of cell division [GO:0051302]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d2hnib1_d2e1hb1__1			Euryarchaeota	Euryarchaeota	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	cellular protein modification process [GO:0006464]	cellular protein modification process [GO:0006464]			ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d2hnkc1_d3hceb1__1		Metazoa	Spirochaetes	Chordata	O-methyltransferase activity [GO:0008171]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]		catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	O-methyltransferase activity [GO:0008171]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d2hnla2_d1byeb1__1	Metazoa	Viridiplantae	Nematoda (roundworms)	Streptophyta	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]		glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]		cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	glutathione transferase activity [GO:0004364]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2hnpa__d2qdpa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; protein tyrosine phosphatase activity [GO:0004725]; cellular response to cytokine stimulus [GO:0071345]; protein dephosphorylation [GO:0006470]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cellular response to cytokine stimulus [GO:0071345]; protein dephosphorylation [GO:0006470]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	protein tyrosine phosphatase activity [GO:0004725]
d2hnqa__d3ps5a3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	alpha-beta T cell receptor complex [GO:0042105]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cell adhesion molecule binding [GO:0050839]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; abortive mitotic cell cycle [GO:0033277]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein dephosphorylation [GO:0006470]; regulation of B cell differentiation [GO:0045577]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	abortive mitotic cell cycle [GO:0033277]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein dephosphorylation [GO:0006470]; regulation of B cell differentiation [GO:0045577]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	alpha-beta T cell receptor complex [GO:0042105]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	cell adhesion molecule binding [GO:0050839]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d2hnt.1_d1toc.2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]
d2hnua__d1npoa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; secretory granule [GO:0030141]; neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	extracellular space [GO:0005615]; secretory granule [GO:0030141]; neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; V1A vasopressin receptor binding [GO:0031894]; vasoconstriction [GO:0042310]	positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	vasoconstriction [GO:0042310]	extracellular space [GO:0005615]; secretory granule [GO:0030141]	extracellular space [GO:0005615]; secretory granule [GO:0030141]	neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]	neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; V1A vasopressin receptor binding [GO:0031894]
d2hnub__d2hnvb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; secretory granule [GO:0030141]; neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	extracellular space [GO:0005615]; secretory granule [GO:0030141]; neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	extracellular space [GO:0005615]; secretory granule [GO:0030141]	extracellular space [GO:0005615]; secretory granule [GO:0030141]	neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]	neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]
d2hnvc__d2hnwc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; secretory granule [GO:0030141]; neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	extracellular space [GO:0005615]; secretory granule [GO:0030141]; neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	extracellular space [GO:0005615]; secretory granule [GO:0030141]	extracellular space [GO:0005615]; secretory granule [GO:0030141]	neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]	neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]
d2hnwb__d2bn2a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; secretory granule [GO:0030141]; neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	extracellular space [GO:0005615]; secretory granule [GO:0030141]; neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; V1A vasopressin receptor binding [GO:0031894]; vasoconstriction [GO:0042310]	positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	vasoconstriction [GO:0042310]	extracellular space [GO:0005615]; secretory granule [GO:0030141]	extracellular space [GO:0005615]; secretory granule [GO:0030141]	neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]	neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; V1A vasopressin receptor binding [GO:0031894]
d2hnwe__d1jk6a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; secretory granule [GO:0030141]; neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	extracellular space [GO:0005615]; secretory granule [GO:0030141]; neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; V1A vasopressin receptor binding [GO:0031894]; vasoconstriction [GO:0042310]	positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	vasoconstriction [GO:0042310]	extracellular space [GO:0005615]; secretory granule [GO:0030141]	extracellular space [GO:0005615]; secretory granule [GO:0030141]	neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]	neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; V1A vasopressin receptor binding [GO:0031894]
d2hoba__d1fiz.1__1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	acrosomal matrix [GO:0043159]; protein-containing complex [GO:0032991]; amidase activity [GO:0004040]; drug binding [GO:0008144]; fucose binding [GO:0042806]; mannose binding [GO:0005537]; serine-type endopeptidase activity [GO:0004252]; acrosome reaction [GO:0007340]; activation of adenylate cyclase activity [GO:0007190]; single fertilization [GO:0007338]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	acrosome reaction [GO:0007340]; activation of adenylate cyclase activity [GO:0007190]; single fertilization [GO:0007338]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	acrosomal matrix [GO:0043159]; protein-containing complex [GO:0032991]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	amidase activity [GO:0004040]; drug binding [GO:0008144]; fucose binding [GO:0042806]; mannose binding [GO:0005537]; serine-type endopeptidase activity [GO:0004252]
d2hoha__d1i3ia___1	Fungi	Fungi	Ascomycota	Ascomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d2hohd__d2f4ya___1	Fungi		Ascomycota	Firmicutes	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d2hora__d4adcc___1	Viridiplantae		Streptophyta	Proteobacteria	vacuole [GO:0005773]; alliin lyase activity [GO:0047654]	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]		arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]	vacuole [GO:0005773]		alliin lyase activity [GO:0047654]	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]
d2hoxc__d2zc0c___1	Viridiplantae		Streptophyta	Euryarchaeota	vacuole [GO:0005773]; alliin lyase activity [GO:0047654]	alanine-glyoxylate transaminase activity [GO:0008453]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]		biosynthetic process [GO:0009058]	vacuole [GO:0005773]		alliin lyase activity [GO:0047654]	alanine-glyoxylate transaminase activity [GO:0008453]; pyridoxal phosphate binding [GO:0030170]
d2hoxd__d3tatf___1	Viridiplantae		Streptophyta	Proteobacteria	vacuole [GO:0005773]; alliin lyase activity [GO:0047654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aromatic-amino-acid:2-oxoglutarate aminotransferase activity [GO:0008793]; identical protein binding [GO:0042802]; L-leucine:2-oxoglutarate aminotransferase activity [GO:0050048]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; aspartate biosynthetic process [GO:0006532]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]; leucine biosynthetic process [GO:0009098]; tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate [GO:0019292]		aspartate biosynthetic process [GO:0006532]; leucine biosynthetic process [GO:0009098]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]; tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate [GO:0019292]	vacuole [GO:0005773]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	alliin lyase activity [GO:0047654]	aromatic-amino-acid:2-oxoglutarate aminotransferase activity [GO:0008793]; identical protein binding [GO:0042802]; L-leucine:2-oxoglutarate aminotransferase activity [GO:0050048]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d2hp1a__d3aowa___1			Cyanobacteria	Euryarchaeota	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]		glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d2hp2a__d1pmma___1			Cyanobacteria	Proteobacteria	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]
d2hp4b__d2ak4e1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]; antigen processing and presentation [GO:0019882]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; immune response [GO:0006955]; regulation of immune response [GO:0050776]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; immune response [GO:0006955]; regulation of immune response [GO:0050776]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2hp4b__d4pjgd___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]; antigen processing and presentation [GO:0019882]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; immune response [GO:0006955]; regulation of immune response [GO:0050776]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; immune response [GO:0006955]; regulation of immune response [GO:0050776]; T cell activation [GO:0042110]; T cell mediated immunity [GO:0002456]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; MHC class I protein complex binding [GO:0023024]; protein kinase binding [GO:0019901]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2hpaa__d1t8pa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]; adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]
d2hpdb__d4bjkc1__1			Firmicutes		cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d2hpfa__d4q5ma1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2hq5b1_d2g7sa1__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]	negative regulation of transcription, DNA-templated [GO:0045892]				DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d2hq6a1_d4r3fa___1	Metazoa	Fungi	Chordata	Ascomycota	catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654]; U2-type precatalytic spliceosome [GO:0071005]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	protein folding [GO:0006457]	catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654]; U2-type precatalytic spliceosome [GO:0071005]		peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2hqha__d2cp5a1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; cell cortex [GO:0005938]; cell cortex region [GO:0099738]; centriolar subdistal appendage [GO:0120103]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dynein complex [GO:0030286]; intercellular bridge [GO:0045171]; kinetochore [GO:0000776]; membrane [GO:0016020]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; spindle [GO:0005819]; spindle pole [GO:0000922]; microtubule binding [GO:0008017]; motor activity [GO:0003774]; protein kinase binding [GO:0019901]; tau protein binding [GO:0048156]; tubulin binding [GO:0015631]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell division [GO:0051301]; centriole-centriole cohesion [GO:0010457]; ciliary basal body-plasma membrane docking [GO:0097711]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; establishment of mitotic spindle orientation [GO:0000132]; G2/M transition of mitotic cell cycle [GO:0000086]; IRE1-mediated unfolded protein response [GO:0036498]; maintenance of synapse structure [GO:0099558]; microtubule anchoring at centrosome [GO:0034454]; mitotic cell cycle [GO:0000278]; motor behavior [GO:0061744]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuromuscular process [GO:0050905]; neuron cellular homeostasis [GO:0070050]; neuron projection maintenance [GO:1990535]; non-motile cilium assembly [GO:1905515]; nuclear envelope disassembly [GO:0051081]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuromuscular junction development [GO:1904398]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic spindle organization [GO:0060236]; retrograde transport, endosome to Golgi [GO:0042147]; transport along microtubule [GO:0010970]; ventral spinal cord development [GO:0021517]	centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; intermediate filament [GO:0005882]; kinetochore [GO:0000776]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nuclear envelope [GO:0005635]; ruffle [GO:0001726]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116]; protein transport into plasma membrane raft [GO:0044861]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell division [GO:0051301]; centriole-centriole cohesion [GO:0010457]; ciliary basal body-plasma membrane docking [GO:0097711]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; establishment of mitotic spindle orientation [GO:0000132]; G2/M transition of mitotic cell cycle [GO:0000086]; IRE1-mediated unfolded protein response [GO:0036498]; maintenance of synapse structure [GO:0099558]; microtubule anchoring at centrosome [GO:0034454]; mitotic cell cycle [GO:0000278]; motor behavior [GO:0061744]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuromuscular process [GO:0050905]; neuron cellular homeostasis [GO:0070050]; neuron projection maintenance [GO:1990535]; non-motile cilium assembly [GO:1905515]; nuclear envelope disassembly [GO:0051081]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuromuscular junction development [GO:1904398]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic spindle organization [GO:0060236]; retrograde transport, endosome to Golgi [GO:0042147]; transport along microtubule [GO:0010970]; ventral spinal cord development [GO:0021517]	microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116]; protein transport into plasma membrane raft [GO:0044861]	axon [GO:0030424]; cell [GO:0005623]; cell cortex [GO:0005938]; cell cortex region [GO:0099738]; centriolar subdistal appendage [GO:0120103]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dynein complex [GO:0030286]; intercellular bridge [GO:0045171]; kinetochore [GO:0000776]; membrane [GO:0016020]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; spindle [GO:0005819]; spindle pole [GO:0000922]	centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; intermediate filament [GO:0005882]; kinetochore [GO:0000776]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nuclear envelope [GO:0005635]; ruffle [GO:0001726]	microtubule binding [GO:0008017]; motor activity [GO:0003774]; protein kinase binding [GO:0019901]; tau protein binding [GO:0048156]; tubulin binding [GO:0015631]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270]
d2hqoa__d2pmca___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]	metal ion binding [GO:0046872]
d2hqob__d1zita___1			Proteobacteria	Aquificae	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]			DNA binding [GO:0003677]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d2hqob__d2b1jb___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		cytosol [GO:0005829]	DNA binding [GO:0003677]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d2hqra2_d2zxjb___1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2hqrb2_d2k4ja1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2hqsd1_d2ivza1__1			Proteobacteria	Proteobacteria	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]; cell cycle [GO:0007049]; cell division [GO:0051301]	extrachromosomal circular DNA [GO:0005727]; protein-containing complex [GO:0032991]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; pathogenesis [GO:0009405]	cell cycle [GO:0007049]; cell division [GO:0051301]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; pathogenesis [GO:0009405]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]	extrachromosomal circular DNA [GO:0005727]; protein-containing complex [GO:0032991]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]
d2hqsf1_d2w8bb2__1			Proteobacteria	Proteobacteria	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]; cell cycle [GO:0007049]; cell division [GO:0051301]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]; cell cycle [GO:0007049]; cell division [GO:0051301]	cell cycle [GO:0007049]; cell division [GO:0051301]	cell cycle [GO:0007049]; cell division [GO:0051301]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]		
d2hqsg2_d2w8bc___1			Proteobacteria	Proteobacteria	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]; cell cycle [GO:0007049]; cell division [GO:0051301]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]; cell cycle [GO:0007049]; cell division [GO:0051301]	cell cycle [GO:0007049]; cell division [GO:0051301]	cell cycle [GO:0007049]; cell division [GO:0051301]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]		
d2hqtd__d4zbab2__1	Fungi	Fungi	Ascomycota	Basidiomycota	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]; enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]; positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]		positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]		enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]	
d2hqtl__d2hqtr___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]; enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]; positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]; enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]; positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]	enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]	enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]
d2hqtp__d4nhzi2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]; enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]; positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	transferase activity [GO:0016740]	positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]		enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]	transferase activity [GO:0016740]
d2hqub__d3i93a1__1	Metazoa		Chordata	Actinobacteria	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2hqub__d4oopc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]	dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2hqyb1_d2jlmf1__1			Bacteroidetes	Proteobacteria		N-acetyltransferase activity [GO:0008080]						N-acetyltransferase activity [GO:0008080]
d2hqyb2_d2gdba___1			Bacteroidetes									
d2hr1a__d5xvka___1		Metazoa	Proteobacteria	Chordata	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nicotinamide N-methyltransferase activity [GO:0008112]; animal organ regeneration [GO:0031100]; methylation [GO:0032259]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]	DNA restriction-modification system [GO:0009307]	animal organ regeneration [GO:0031100]; methylation [GO:0032259]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	nicotinamide N-methyltransferase activity [GO:0008112]
d2hr7a1_d2wqwb1__1	Metazoa		Chordata	Firmicutes	axon [GO:0030424]; caveola [GO:0005901]; dendrite membrane [GO:0032590]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; insulin receptor complex [GO:0005899]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; cargo receptor activity [GO:0038024]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; insulin receptor substrate binding [GO:0043560]; insulin-activated receptor activity [GO:0005009]; insulin-like growth factor I binding [GO:0031994]; insulin-like growth factor II binding [GO:0031995]; insulin-like growth factor receptor binding [GO:0005159]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; PTB domain binding [GO:0051425]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of MAPK activity [GO:0000187]; activation of protein kinase activity [GO:0032147]; activation of protein kinase B activity [GO:0032148]; adrenal gland development [GO:0030325]; amyloid-beta clearance [GO:0097242]; anatomical structure development [GO:0048856]; carbohydrate metabolic process [GO:0005975]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; dendritic spine maintenance [GO:0097062]; epidermis development [GO:0008544]; exocrine pancreas development [GO:0031017]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose homeostasis [GO:0042593]; heart morphogenesis [GO:0003007]; insulin receptor signaling pathway [GO:0008286]; learning [GO:0007612]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; memory [GO:0007613]; neuron projection maintenance [GO:1990535]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of developmental growth [GO:0048639]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of meiotic cell cycle [GO:0051446]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of respiratory burst [GO:0060267]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein heterotetramerization [GO:0051290]; protein phosphorylation [GO:0006468]; receptor-mediated endocytosis [GO:0006898]; regulation of embryonic development [GO:0045995]; regulation of female gonad development [GO:2000194]; regulation of transcription, DNA-templated [GO:0006355]; transformation of host cell by virus [GO:0019087]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	activation of MAPK activity [GO:0000187]; activation of protein kinase activity [GO:0032147]; activation of protein kinase B activity [GO:0032148]; adrenal gland development [GO:0030325]; amyloid-beta clearance [GO:0097242]; anatomical structure development [GO:0048856]; carbohydrate metabolic process [GO:0005975]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; dendritic spine maintenance [GO:0097062]; epidermis development [GO:0008544]; exocrine pancreas development [GO:0031017]; glucose homeostasis [GO:0042593]; G protein-coupled receptor signaling pathway [GO:0007186]; heart morphogenesis [GO:0003007]; insulin receptor signaling pathway [GO:0008286]; learning [GO:0007612]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; memory [GO:0007613]; neuron projection maintenance [GO:1990535]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of developmental growth [GO:0048639]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of meiotic cell cycle [GO:0051446]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of respiratory burst [GO:0060267]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein heterotetramerization [GO:0051290]; protein phosphorylation [GO:0006468]; receptor-mediated endocytosis [GO:0006898]; regulation of embryonic development [GO:0045995]; regulation of female gonad development [GO:2000194]; regulation of transcription, DNA-templated [GO:0006355]; transformation of host cell by virus [GO:0019087]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	pathogenesis [GO:0009405]	axon [GO:0030424]; caveola [GO:0005901]; dendrite membrane [GO:0032590]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; insulin receptor complex [GO:0005899]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; cargo receptor activity [GO:0038024]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; insulin-activated receptor activity [GO:0005009]; insulin binding [GO:0043559]; insulin-like growth factor I binding [GO:0031994]; insulin-like growth factor II binding [GO:0031995]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor substrate binding [GO:0043560]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein tyrosine kinase activity [GO:0004713]; PTB domain binding [GO:0051425]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	heparin binding [GO:0008201]; lipid binding [GO:0008289]
d2hr7a3_d1nqla2__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; caveola [GO:0005901]; dendrite membrane [GO:0032590]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; insulin receptor complex [GO:0005899]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; cargo receptor activity [GO:0038024]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; insulin receptor substrate binding [GO:0043560]; insulin-activated receptor activity [GO:0005009]; insulin-like growth factor I binding [GO:0031994]; insulin-like growth factor II binding [GO:0031995]; insulin-like growth factor receptor binding [GO:0005159]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; PTB domain binding [GO:0051425]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of MAPK activity [GO:0000187]; activation of protein kinase activity [GO:0032147]; activation of protein kinase B activity [GO:0032148]; adrenal gland development [GO:0030325]; amyloid-beta clearance [GO:0097242]; anatomical structure development [GO:0048856]; carbohydrate metabolic process [GO:0005975]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; dendritic spine maintenance [GO:0097062]; epidermis development [GO:0008544]; exocrine pancreas development [GO:0031017]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose homeostasis [GO:0042593]; heart morphogenesis [GO:0003007]; insulin receptor signaling pathway [GO:0008286]; learning [GO:0007612]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; memory [GO:0007613]; neuron projection maintenance [GO:1990535]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of developmental growth [GO:0048639]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of meiotic cell cycle [GO:0051446]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of respiratory burst [GO:0060267]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein heterotetramerization [GO:0051290]; protein phosphorylation [GO:0006468]; receptor-mediated endocytosis [GO:0006898]; regulation of embryonic development [GO:0045995]; regulation of female gonad development [GO:2000194]; regulation of transcription, DNA-templated [GO:0006355]; transformation of host cell by virus [GO:0019087]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	clathrin-coated vesicle membrane [GO:0030665]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; receptor complex [GO:0043235]; calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; growth factor activity [GO:0008083]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; canonical Wnt signaling pathway [GO:0060070]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; ERK1 and ERK2 cascade [GO:0070371]; mammary gland alveolus development [GO:0060749]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of secretion [GO:0051048]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet degranulation [GO:0002576]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of gene expression [GO:0010628]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of calcium ion import [GO:0090279]; regulation of cell motility [GO:2000145]; regulation of protein localization to cell surface [GO:2000008]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase activity [GO:0032147]; activation of protein kinase B activity [GO:0032148]; adrenal gland development [GO:0030325]; amyloid-beta clearance [GO:0097242]; anatomical structure development [GO:0048856]; carbohydrate metabolic process [GO:0005975]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; dendritic spine maintenance [GO:0097062]; epidermis development [GO:0008544]; exocrine pancreas development [GO:0031017]; glucose homeostasis [GO:0042593]; G protein-coupled receptor signaling pathway [GO:0007186]; heart morphogenesis [GO:0003007]; insulin receptor signaling pathway [GO:0008286]; learning [GO:0007612]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; memory [GO:0007613]; neuron projection maintenance [GO:1990535]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of developmental growth [GO:0048639]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of meiotic cell cycle [GO:0051446]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of respiratory burst [GO:0060267]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein heterotetramerization [GO:0051290]; protein phosphorylation [GO:0006468]; receptor-mediated endocytosis [GO:0006898]; regulation of embryonic development [GO:0045995]; regulation of female gonad development [GO:2000194]; regulation of transcription, DNA-templated [GO:0006355]; transformation of host cell by virus [GO:0019087]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; canonical Wnt signaling pathway [GO:0060070]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; ERK1 and ERK2 cascade [GO:0070371]; mammary gland alveolus development [GO:0060749]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of secretion [GO:0051048]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet degranulation [GO:0002576]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of gene expression [GO:0010628]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; regulation of calcium ion import [GO:0090279]; regulation of cell motility [GO:2000145]; regulation of protein localization to cell surface [GO:2000008]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; signal transduction [GO:0007165]	axon [GO:0030424]; caveola [GO:0005901]; dendrite membrane [GO:0032590]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; insulin receptor complex [GO:0005899]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	clathrin-coated vesicle membrane [GO:0030665]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; receptor complex [GO:0043235]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; cargo receptor activity [GO:0038024]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; insulin-activated receptor activity [GO:0005009]; insulin binding [GO:0043559]; insulin-like growth factor I binding [GO:0031994]; insulin-like growth factor II binding [GO:0031995]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor substrate binding [GO:0043560]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein tyrosine kinase activity [GO:0004713]; PTB domain binding [GO:0051425]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; growth factor activity [GO:0008083]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]
d2hr8b__d2e17a___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2hrcb__d2xwqc1__1	Metazoa		Chordata	Euryarchaeota	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]; anaerobic cobalamin biosynthetic process [GO:0019251]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	anaerobic cobalamin biosynthetic process [GO:0019251]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]
d2hrcb__d3hcpb___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d2hrde__d1odjb___1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	transferase activity, transferring pentosyl groups [GO:0016763]; nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]		uridine phosphorylase activity [GO:0004850]	transferase activity, transferring pentosyl groups [GO:0016763]
d2hrde__d4txjc___1		Metazoa	Proteobacteria	Platyhelminthes	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	uridine phosphorylase activity [GO:0004850]	uridine phosphorylase activity [GO:0004850]
d2hreb__d2dj5a2__1	Metazoa		Chordata	Euryarchaeota	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]; anaerobic cobalamin biosynthetic process [GO:0019251]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	anaerobic cobalamin biosynthetic process [GO:0019251]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]
d2hrfa1_d1pn9a2__1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; copper ion binding [GO:0005507]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cytoplasm [GO:0005737]; DDT-dehydrochlorinase activity [GO:0018833]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]	cytoplasm [GO:0005737]	copper ion binding [GO:0005507]	DDT-dehydrochlorinase activity [GO:0018833]; glutathione transferase activity [GO:0004364]
d2hrfa1_d2vcvo1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; copper ion binding [GO:0005507]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	copper ion binding [GO:0005507]	glutathione transferase activity [GO:0004364]
d2hrga2_d1xb3a___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2hrga3_d1sjmb2__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2hrha1_d1as6c1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2hrha2_d3t71a2__1	Fungi	Fungi	Basidiomycota	Basidiomycota	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]					copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2hrha3_d4n28a1__1	Fungi	Metazoa	Basidiomycota	Chordata	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; chromatin-mediated maintenance of transcription [GO:0048096]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]		cellular response to leukemia inhibitory factor [GO:1990830]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin organization [GO:0006325]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]
d2hrkb__d2glrb1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]; enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]; positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]
d2hrna1_d4ofnb1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; copper ion binding [GO:0005507]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	transferase activity [GO:0016740]	cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]		cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]		copper ion binding [GO:0005507]	transferase activity [GO:0016740]
d2hrph2_d2xtjd___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor recycling [GO:0001920]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of receptor recycling [GO:0001920]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]
d2hrpl2_d1fl3h1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2hrpm2_d3mlxm1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d2hrpn2_d1kn2l1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2hrqb__d3g0dd2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2hrqc__d2va9b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	acetylcholinesterase activity [GO:0003990]
d2hrqe__d3rk4a1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	response to toxic substance [GO:0009636]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]		carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]	haloalkane dehalogenase activity [GO:0018786]
d2hrua2_d5avmc2__1			Thermotogae	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]
d2hrva__d2bdba___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular space [GO:0005615]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2hrvb__d1qq4a___1				Proteobacteria	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	serine-type endopeptidase activity [GO:0004252]
d2hs0a1_d1clid1__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytosol [GO:0005829]; ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]
d2hs0a1_d3u0oa1__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]; selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]
d2hs1b__d5p3ea___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2hs2b__d1ppme___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2hs3a1_d5avmb2__1			Thermotogae	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]
d2hs4a3_d3u0ob2__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]; selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]
d2hs9a1_d129la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2hs9a1_d1lmpa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2hsda__d1qmgc2__1		Viridiplantae	Actinobacteria	Streptophyta	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; C21-steroid hormone metabolic process [GO:0008207]	chloroplast [GO:0009507]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	C21-steroid hormone metabolic process [GO:0008207]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		chloroplast [GO:0009507]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]
d2hsec2_d1orti2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d2hsya__d2wfca1__1	Fungi	Metazoa	Ascomycota	Annelida	cell [GO:0005623]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; glutathione metabolic process [GO:0006749]; glycerol ether metabolic process [GO:0006662]; protein deglutathionylation [GO:0080058]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; sulfate assimilation [GO:0000103]; vacuole fusion, non-autophagic [GO:0042144]; vacuole inheritance [GO:0000011]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; glutathione metabolic process [GO:0006749]; glycerol ether metabolic process [GO:0006662]; protein deglutathionylation [GO:0080058]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; sulfate assimilation [GO:0000103]; vacuole fusion, non-autophagic [GO:0042144]; vacuole inheritance [GO:0000011]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	cell [GO:0005623]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2ht2d1_d1ruql1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ht2d2_d4beld1__1	Metazoa	Metazoa	Chordata	Chordata		dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]		aspartic-type endopeptidase activity [GO:0004190]
d2ht2d2_d4k71b2__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ht2f1_d1iilh1__1	Metazoa	Metazoa	Chordata	Chordata		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]		angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2ht2f2_d2osll2__1	Metazoa	Metazoa	Chordata	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ht3d1_d4fzel2__1	Metazoa		Chordata									
d2ht3f2_d1d6ea1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d2ht4d1_d1cg9a1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ht4f1_d1a7ol___1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ht4f1_d5uy3b1__1	Metazoa		Chordata									
d2ht9b__d4gqcc1__1	Metazoa		Chordata	Crenarchaeota	cell [GO:0005623]; dendrite [GO:0030425]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 2 iron, 2 sulfur cluster binding [GO:0051537]; arsenate reductase (glutaredoxin) activity [GO:0008794]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; metal ion binding [GO:0046872]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; aging [GO:0007568]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; cellular response to superoxide [GO:0071451]; DNA protection [GO:0042262]; glutathione metabolic process [GO:0006749]; regulation of signal transduction [GO:0009966]; regulation of transcription, DNA-templated [GO:0006355]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to redox state [GO:0051775]; response to temperature stimulus [GO:0009266]	cell [GO:0005623]; peroxidase activity [GO:0004601]; cell redox homeostasis [GO:0045454]	aging [GO:0007568]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; cellular response to superoxide [GO:0071451]; DNA protection [GO:0042262]; glutathione metabolic process [GO:0006749]; regulation of signal transduction [GO:0009966]; regulation of transcription, DNA-templated [GO:0006355]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to redox state [GO:0051775]; response to temperature stimulus [GO:0009266]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; dendrite [GO:0030425]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]	2 iron, 2 sulfur cluster binding [GO:0051537]; arsenate reductase (glutaredoxin) activity [GO:0008794]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; metal ion binding [GO:0046872]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	peroxidase activity [GO:0004601]
d2htha__d5chwh1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2htkd1_d4irjc1__1	Metazoa	Metazoa	Chordata	Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2htkd2_d2aw2x2__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine binding [GO:0019955]; tumor necrosis factor-activated receptor activity [GO:0005031]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of adaptive immune memory response [GO:1905675]; negative regulation of alpha-beta T cell proliferation [GO:0046642]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell migration [GO:2000406]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of adaptive immune memory response [GO:1905675]; negative regulation of alpha-beta T cell proliferation [GO:0046642]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell migration [GO:2000406]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		cytokine binding [GO:0019955]; tumor necrosis factor-activated receptor activity [GO:0005031]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2htkf1_d1ap2b___1	Metazoa		Chordata									
d2htkf2_d2a6jb2__1	Metazoa		Chordata									
d2htlf2_d5k9qv1__1	Metazoa		Chordata	Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d2htnb__d3a68d___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2htnf__d2fhaa___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2htva__d1nmcn___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2htvb__d4gzwd___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2htyb__d1mwea___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2htyc__d1ncdn___1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2htyf__d1w8na3__1			Negarnaviricota	Actinobacteria	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d2hu0a__d2qwha___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2hu0b__d2fhra2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d2hu0c__d3k3ak___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2hu0c__d5f9ta2__1			Negarnaviricota	Firmicutes	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d2hu0d__d4gdid___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2hu0d__d5humd___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2hu0g__d3k39l___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2hu1a__d5xpfa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2hu4a__d3k39k___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2hu4f__d1v3db___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d2hu4h__d5huka1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2hu5b1_d3muna1__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]		serine-type peptidase activity [GO:0008236]	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d2hu6a__d3kmeb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d2hu7a2_d1xroa___1			Crenarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	aminopeptidase activity [GO:0004177]			cytoplasm [GO:0005737]		serine-type peptidase activity [GO:0008236]	aminopeptidase activity [GO:0004177]
d2hu7b2_d1fssa___1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]		acetylcholine catabolic process in synaptic cleft [GO:0001507]	cytoplasm [GO:0005737]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	serine-type peptidase activity [GO:0008236]	acetylcholinesterase activity [GO:0003990]
d2hu8a2_d3v1ma___1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]		serine-type peptidase activity [GO:0008236]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]
d2huba__d2oe7x___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2huca__d1qm6b1__1			Firmicutes	Firmicutes	phosphatidylcholine phospholipase C activity [GO:0034480]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	hemolysis in other organism [GO:0044179]	hemolysis in other organism [GO:0044179]		extracellular region [GO:0005576]	phosphatidylcholine phospholipase C activity [GO:0034480]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d2hula__d1flqa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2huma__d1jisa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2hunb__d4c7kd___1		Metazoa	Euryarchaeota	Chordata	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]; nucleotide-sugar metabolic process [GO:0009225]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	nucleotide-sugar metabolic process [GO:0009225]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d2huoa1_d5b4lb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; inclusion body [GO:0016234]; aldo-keto reductase (NADP) activity [GO:0004033]; ferric iron binding [GO:0008199]; inositol oxygenase activity [GO:0050113]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H [GO:0016651]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [GO:0016701]; inositol catabolic process [GO:0019310]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	inositol catabolic process [GO:0019310]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytoplasm [GO:0005737]; inclusion body [GO:0016234]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	aldo-keto reductase (NADP) activity [GO:0004033]; ferric iron binding [GO:0008199]; inositol oxygenase activity [GO:0050113]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H [GO:0016651]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [GO:0016701]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d2huqa__d2dv5a___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2hura__d3bbce___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]
d2hura__d4s0mg___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2hurb__d3ztpa___1			Proteobacteria	Aquificae	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2hure__d5u2ie1__1			Proteobacteria	Heterolobosea	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d2hurf__d4uofb___1		Metazoa	Proteobacteria	Arthropoda	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d2huxb__d2e8ra___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2huza__d5us1k1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; late endosome [GO:0005770]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; identical protein binding [GO:0042802]; monosaccharide binding [GO:0048029]; cellular response to leukemia inhibitory factor [GO:1990830]; glucosamine metabolic process [GO:0006041]; liver development [GO:0001889]; N-acetylglucosamine metabolic process [GO:0006044]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	aminoglycoside 2'-N-acetyltransferase activity [GO:0047921]; response to antibiotic [GO:0046677]	cellular response to leukemia inhibitory factor [GO:1990830]; glucosamine metabolic process [GO:0006041]; liver development [GO:0001889]; N-acetylglucosamine metabolic process [GO:0006044]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	response to antibiotic [GO:0046677]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; late endosome [GO:0005770]		glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; identical protein binding [GO:0042802]; monosaccharide binding [GO:0048029]	aminoglycoside 2'-N-acetyltransferase activity [GO:0047921]
d2huzb__d4jwpa1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; late endosome [GO:0005770]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; identical protein binding [GO:0042802]; monosaccharide binding [GO:0048029]; cellular response to leukemia inhibitory factor [GO:1990830]; glucosamine metabolic process [GO:0006041]; liver development [GO:0001889]; N-acetylglucosamine metabolic process [GO:0006044]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]	cellular response to leukemia inhibitory factor [GO:1990830]; glucosamine metabolic process [GO:0006041]; liver development [GO:0001889]; N-acetylglucosamine metabolic process [GO:0006044]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; late endosome [GO:0005770]		glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; identical protein binding [GO:0042802]; monosaccharide binding [GO:0048029]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]
d2hv0a__d1yk3d___1				Actinobacteria		acyl-CoA hydrolase activity [GO:0047617]; N-acyltransferase activity [GO:0016410]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; siderophore biosynthetic process from catechol [GO:0019540]		siderophore biosynthetic process from catechol [GO:0019540]				acyl-CoA hydrolase activity [GO:0047617]; N-acyltransferase activity [GO:0016410]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2hv1a__d3nhqe1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]; aryl hydrocarbon receptor binding [GO:0017162]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; nuclear receptor activity [GO:0004879]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; cell differentiation [GO:0030154]; embryonic placenta development [GO:0001892]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; xenobiotic metabolic process [GO:0006805]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cell differentiation [GO:0030154]; embryonic placenta development [GO:0001892]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; xenobiotic metabolic process [GO:0006805]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]		aryl hydrocarbon receptor binding [GO:0017162]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; nuclear receptor activity [GO:0004879]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d2hv4a__d2c1df___1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2hveb__d3ztqd___1	Metazoa		Chordata	Aquificae	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]; cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2hvec__d1mn7b___1	Metazoa		Chordata		cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]; cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2hvec__d3ztse___1	Metazoa		Chordata	Aquificae	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]; cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2hvja1_d1pqzb___1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	voltage-gated potassium channel complex [GO:0008076]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2hvja1_d1s5ih1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	voltage-gated potassium channel complex [GO:0008076]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2hvjb1_d4fq2l1__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2hvjb2_d2w0lb1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2hvka2_d3v7ma2__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	voltage-gated potassium channel complex [GO:0008076]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2hvma__d3m7sa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	vacuole [GO:0005773]; chitinase activity [GO:0004568]; lysozyme activity [GO:0003796]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	alpha-amylase inhibitor activity [GO:0015066]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	vacuole [GO:0005773]		chitinase activity [GO:0004568]; lysozyme activity [GO:0003796]	alpha-amylase inhibitor activity [GO:0015066]
d2hvna__d3uzxa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytosol [GO:0005829]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]
d2hvoa__d3b3ea___1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]		C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	
d2hvxa__d3zzca___1	Metazoa		Chordata		cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptide binding [GO:0042277]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; angiotensin maturation [GO:0002003]; basement membrane disassembly [GO:0034769]; cellular response to glucose stimulus [GO:0071333]; extracellular matrix disassembly [GO:0022617]; interleukin-1 beta biosynthetic process [GO:0050720]; midbrain development [GO:0030901]; positive regulation of angiogenesis [GO:0045766]; regulation of inflammatory response [GO:0050727]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	angiotensin maturation [GO:0002003]; basement membrane disassembly [GO:0034769]; cellular response to glucose stimulus [GO:0071333]; extracellular matrix disassembly [GO:0022617]; interleukin-1 beta biosynthetic process [GO:0050720]; midbrain development [GO:0030901]; positive regulation of angiogenesis [GO:0045766]; regulation of inflammatory response [GO:0050727]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	peptide binding [GO:0042277]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2hw5a__d1szoc___1	Metazoa		Chordata	Actinobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	fatty acid beta-oxidation [GO:0006635]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]
d2hw5b__d3h81a___1	Metazoa		Chordata	Actinobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	cell wall [GO:0005618]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	fatty acid beta-oxidation [GO:0006635]	fatty acid beta-oxidation [GO:0006635]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell wall [GO:0005618]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]
d2hw5c__d1on9d1__1	Metazoa		Chordata	Actinobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]; fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation [GO:0006635]	fatty acid biosynthetic process [GO:0006633]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	acetyl-CoA carboxylase complex [GO:0009317]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]	acetyl-CoA carboxylase activity [GO:0003989]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]
d2hwb1__d2rs3.1__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2hwb1__d5fmos___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	transport of virus in host, cell to cell [GO:0046740]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2hwb3__d4rqpk___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2hwc1__d1vrh.1__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2hwc1__d4sbvc___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; calcium ion binding [GO:0005509]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	calcium ion binding [GO:0005509]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]
d2hwc3__d4cewb___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2hwf1__d1c8m3___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2hwf1__d1ddlc___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d2hx7a__d1pf3a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d2hx7b__d1kcwa5__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	oxidation-reduction process [GO:0055114]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d2hxaa__d2bw4a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2hxda__d4apzg___1			Euryarchaeota	Firmicutes	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2hxgc1_d4r1qd2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytoplasm [GO:0005737]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d2hy5a1_d1rhxa___1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	sulfurtransferase complex [GO:1990228]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]	sulfurtransferase complex [GO:1990228]		
d2hy5b1_d2hybf___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]		
d2hybb__d2hybj___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]		
d2hybc__d2hybh___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]		
d2hybd__d2hybr___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]		
d2hybf__d2d1pc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]; sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]		sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]
d2hybg__d2d1pi___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]; sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]		sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]
d2hybh__d2hybp___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]		
d2hybj__d2pd2a___1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]		tRNA wobble position uridine thiolation [GO:0002143]		cytoplasm [GO:0005737]			
d2hybl__d1rhxa___1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	sulfurtransferase complex [GO:1990228]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]	sulfurtransferase complex [GO:1990228]		
d2hybl__d2d1pd2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]; sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]		sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]
d2hybn__d1x9aa___1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	sulfurtransferase complex [GO:1990228]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]	sulfurtransferase complex [GO:1990228]		
d2hybp__d2hybi___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]; tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	tRNA wobble position uridine thiolation [GO:0002143]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]		
d2hydb1_d3b5yc1__1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]	ATPase activity [GO:0016887]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]
d2hyqa1_d3miua___1		Viridiplantae	Rhodophyta	Streptophyta	cell [GO:0005623]; carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]			cell [GO:0005623]		carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2hyqb1_d5xfhb___1		Viridiplantae	Rhodophyta	Streptophyta	cell [GO:0005623]; carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]	carbohydrate binding [GO:0030246]			cell [GO:0005623]		carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]	carbohydrate binding [GO:0030246]
d2hyra1_d4akdd1__1		Viridiplantae	Rhodophyta	Streptophyta	cell [GO:0005623]; carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]	carbohydrate binding [GO:0030246]			cell [GO:0005623]		carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]	carbohydrate binding [GO:0030246]
d2hyrb1_d4pifb1__1		Viridiplantae	Rhodophyta	Streptophyta	cell [GO:0005623]; carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]	carbohydrate binding [GO:0030246]			cell [GO:0005623]		carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]	carbohydrate binding [GO:0030246]
d2hyua__d1w45b___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell cortex [GO:0005938]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; macropinosome [GO:0044354]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; myelin sheath adaxonal region [GO:0035749]; nucleus [GO:0005634]; PCSK9-AnxA2 complex [GO:1990667]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; sarcolemma [GO:0042383]; Schmidt-Lanterman incisure [GO:0043220]; vesicle [GO:0031982]; bone sialoprotein binding [GO:0044730]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; molecular function regulator [GO:0098772]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipase A2 inhibitor activity [GO:0019834]; protease binding [GO:0002020]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; virion binding [GO:0046790]; voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [GO:0099511]; angiogenesis [GO:0001525]; biomineral tissue development [GO:0031214]; body fluid secretion [GO:0007589]; catabolism by host of symbiont protein [GO:0052362]; collagen fibril organization [GO:0030199]; endocardial cell differentiation [GO:0060956]; fibrinolysis [GO:0042730]; growth plate cartilage development [GO:0003417]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane raft assembly [GO:0001765]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of development of symbiont involved in interaction with host [GO:0044147]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; neutrophil degranulation [GO:0043312]; osteoclast development [GO:0036035]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of low-density lipoprotein particle receptor binding [GO:1905597]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor recycling [GO:0001921]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of vacuole organization [GO:0044090]; positive regulation of vesicle fusion [GO:0031340]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; regulation of plasminogen activation [GO:0010755]; response to thyroid hormone [GO:0097066]; vesicle budding from membrane [GO:0006900]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; blood coagulation [GO:0007596]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of serine-type endopeptidase activity [GO:1900004]	angiogenesis [GO:0001525]; biomineral tissue development [GO:0031214]; body fluid secretion [GO:0007589]; catabolism by host of symbiont protein [GO:0052362]; collagen fibril organization [GO:0030199]; endocardial cell differentiation [GO:0060956]; fibrinolysis [GO:0042730]; growth plate cartilage development [GO:0003417]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane raft assembly [GO:0001765]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of development of symbiont involved in interaction with host [GO:0044147]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; neutrophil degranulation [GO:0043312]; osteoclast development [GO:0036035]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of low-density lipoprotein particle receptor binding [GO:1905597]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of receptor recycling [GO:0001921]; positive regulation of vacuole organization [GO:0044090]; positive regulation of vesicle fusion [GO:0031340]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; regulation of plasminogen activation [GO:0010755]; response to thyroid hormone [GO:0097066]; vesicle budding from membrane [GO:0006900]	blood coagulation [GO:0007596]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of serine-type endopeptidase activity [GO:1900004]	azurophil granule lumen [GO:0035578]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; macropinosome [GO:0044354]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; myelin sheath adaxonal region [GO:0035749]; nucleus [GO:0005634]; PCSK9-AnxA2 complex [GO:1990667]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; sarcolemma [GO:0042383]; Schmidt-Lanterman incisure [GO:0043220]; vesicle [GO:0031982]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]	bone sialoprotein binding [GO:0044730]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium channel activity [GO:0005262]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; molecular function regulator [GO:0098772]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipase A2 inhibitor activity [GO:0019834]; protease binding [GO:0002020]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; virion binding [GO:0046790]; voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [GO:0099511]	actin filament binding [GO:0051015]; calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]
d2hywa__d1w45a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell cortex [GO:0005938]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; macropinosome [GO:0044354]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; myelin sheath adaxonal region [GO:0035749]; nucleus [GO:0005634]; PCSK9-AnxA2 complex [GO:1990667]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; sarcolemma [GO:0042383]; Schmidt-Lanterman incisure [GO:0043220]; vesicle [GO:0031982]; bone sialoprotein binding [GO:0044730]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; molecular function regulator [GO:0098772]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipase A2 inhibitor activity [GO:0019834]; protease binding [GO:0002020]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; virion binding [GO:0046790]; voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [GO:0099511]; angiogenesis [GO:0001525]; biomineral tissue development [GO:0031214]; body fluid secretion [GO:0007589]; catabolism by host of symbiont protein [GO:0052362]; collagen fibril organization [GO:0030199]; endocardial cell differentiation [GO:0060956]; fibrinolysis [GO:0042730]; growth plate cartilage development [GO:0003417]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane raft assembly [GO:0001765]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of development of symbiont involved in interaction with host [GO:0044147]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; neutrophil degranulation [GO:0043312]; osteoclast development [GO:0036035]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of low-density lipoprotein particle receptor binding [GO:1905597]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor recycling [GO:0001921]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of vacuole organization [GO:0044090]; positive regulation of vesicle fusion [GO:0031340]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; regulation of plasminogen activation [GO:0010755]; response to thyroid hormone [GO:0097066]; vesicle budding from membrane [GO:0006900]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; blood coagulation [GO:0007596]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of serine-type endopeptidase activity [GO:1900004]	angiogenesis [GO:0001525]; biomineral tissue development [GO:0031214]; body fluid secretion [GO:0007589]; catabolism by host of symbiont protein [GO:0052362]; collagen fibril organization [GO:0030199]; endocardial cell differentiation [GO:0060956]; fibrinolysis [GO:0042730]; growth plate cartilage development [GO:0003417]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane raft assembly [GO:0001765]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of development of symbiont involved in interaction with host [GO:0044147]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; neutrophil degranulation [GO:0043312]; osteoclast development [GO:0036035]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of low-density lipoprotein particle receptor binding [GO:1905597]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of receptor recycling [GO:0001921]; positive regulation of vacuole organization [GO:0044090]; positive regulation of vesicle fusion [GO:0031340]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; regulation of plasminogen activation [GO:0010755]; response to thyroid hormone [GO:0097066]; vesicle budding from membrane [GO:0006900]	blood coagulation [GO:0007596]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of serine-type endopeptidase activity [GO:1900004]	azurophil granule lumen [GO:0035578]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; macropinosome [GO:0044354]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; myelin sheath adaxonal region [GO:0035749]; nucleus [GO:0005634]; PCSK9-AnxA2 complex [GO:1990667]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; sarcolemma [GO:0042383]; Schmidt-Lanterman incisure [GO:0043220]; vesicle [GO:0031982]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]	bone sialoprotein binding [GO:0044730]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium channel activity [GO:0005262]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; molecular function regulator [GO:0098772]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipase A2 inhibitor activity [GO:0019834]; protease binding [GO:0002020]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; virion binding [GO:0046790]; voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [GO:0099511]	actin filament binding [GO:0051015]; calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]
d2hz2a__d2qrwl___1			Cyanobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d2hz3a__d1yh9a___1		Metazoa	Cyanobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2hz9a1_d1afcf___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2hzca1_d5szwa1__1	Metazoa	Metazoa	Chordata	Chordata	commitment complex [GO:0000243]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type prespliceosome [GO:0071004]; U2AF [GO:0089701]; C2H2 zinc finger domain binding [GO:0070742]; enzyme binding [GO:0019899]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA 3'-splice site binding [GO:0030628]; RNA binding [GO:0003723]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of RNA splicing [GO:0033120]; RNA export from nucleus [GO:0006405]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of RNA splicing [GO:0033120]; RNA export from nucleus [GO:0006405]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	commitment complex [GO:0000243]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2AF [GO:0089701]; U2-type prespliceosome [GO:0071004]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]	C2H2 zinc finger domain binding [GO:0070742]; enzyme binding [GO:0019899]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA 3'-splice site binding [GO:0030628]; RNA binding [GO:0003723]	AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d2hzfb1_d4cw9b1__1					virion [GO:0019012]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	virion [GO:0019012]	cell [GO:0005623]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d2hzfb1_d4fh8d1__1		Metazoa		Nematoda (roundworms)	virion [GO:0019012]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	virion [GO:0019012]	cell [GO:0005623]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	peroxiredoxin activity [GO:0051920]
d2hzga2_d4e6md2__1			Proteobacteria	Proteobacteria		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d2hzgb1_d2al1b2__1		Fungi	Proteobacteria	Ascomycota		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2hzgb1_d4h2hh1__1			Proteobacteria	Proteobacteria		magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; amino-acid betaine catabolic process [GO:0006579]		amino-acid betaine catabolic process [GO:0006579]				magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d2hzya1_d4qkub1__1	Metazoa		Chordata	Proteobacteria	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]; arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	fumarylacetoacetase activity [GO:0004334]; aromatic amino acid family metabolic process [GO:0009072]	arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	aromatic amino acid family metabolic process [GO:0009072]			fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]	fumarylacetoacetase activity [GO:0004334]
d2hzya2_d4qkud2__1	Metazoa		Chordata	Proteobacteria	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]; arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	fumarylacetoacetase activity [GO:0004334]; aromatic amino acid family metabolic process [GO:0009072]	arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	aromatic amino acid family metabolic process [GO:0009072]			fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]	fumarylacetoacetase activity [GO:0004334]
d2hzyb2_d2wqto___1	Metazoa		Chordata	Proteobacteria	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]; arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	cytoplasm [GO:0005737]; 2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]		cytoplasm [GO:0005737]	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]	2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]
d2hzza__d4ya4w___1		Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2i00a1_d4av7e2__1			Firmicutes	Proteobacteria	N-acetyltransferase activity [GO:0008080]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]					N-acetyltransferase activity [GO:0008080]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]
d2i00b2_d3wr7d___1			Firmicutes	Proteobacteria	N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]					N-acetyltransferase activity [GO:0008080]	N-acetyltransferase activity [GO:0008080]
d2i00c1_d2nsfa2__1			Firmicutes	Actinobacteria	N-acetyltransferase activity [GO:0008080]	metal ion binding [GO:0046872]					N-acetyltransferase activity [GO:0008080]	metal ion binding [GO:0046872]
d2i00e1_d4av7a2__1			Firmicutes	Proteobacteria	N-acetyltransferase activity [GO:0008080]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]					N-acetyltransferase activity [GO:0008080]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]
d2i00e2_d1zo0a1__1		Metazoa	Firmicutes	Chordata	N-acetyltransferase activity [GO:0008080]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; ornithine decarboxylase inhibitor activity [GO:0008073]; protein heterodimerization activity [GO:0046982]; polyamine biosynthetic process [GO:0006596]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of protein catabolic process [GO:0045732]		polyamine biosynthetic process [GO:0006596]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of protein catabolic process [GO:0045732]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	N-acetyltransferase activity [GO:0008080]	enzyme binding [GO:0019899]; ornithine decarboxylase inhibitor activity [GO:0008073]; protein heterodimerization activity [GO:0046982]
d2i03b1_d1orwc1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d2i03b2_d4dnob___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	hydrolase activity [GO:0016787]
d2i03d2_d5ak3a2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2i08a__d3jvtb___1	Metazoa	Metazoa	Chordata	Mollusca	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]
d2i0aa__d1ebwa___1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2i0bb1_d3o28a___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2i0bc__d5nihb___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2i0ca__d3dp6b___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2i0ca__d3ir1f___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]		behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]		axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]		extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	
d2i0da__d3d1xa___1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2i0ia1_d1v62a1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor signaling complex adaptor activity [GO:0030159]; artery smooth muscle contraction [GO:0014824]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; Notch signaling pathway [GO:0007219]; positive regulation of blood pressure [GO:0045777]; vesicle-mediated transport in synapse [GO:0099003]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	artery smooth muscle contraction [GO:0014824]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; Notch signaling pathway [GO:0007219]; positive regulation of blood pressure [GO:0045777]; vesicle-mediated transport in synapse [GO:0099003]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]	cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]	ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]	receptor signaling complex adaptor activity [GO:0030159]
d2i0ka2_d3eub31__1		Metazoa	Actinobacteria	Chordata	FAD binding [GO:0071949]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [GO:0016899]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	FAD binding [GO:0071949]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [GO:0016899]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d2i0qa1_d1v1qa1__1			Ciliophora	Proteobacteria	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	pre-primosome complex [GO:1990099]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269]; plasmid maintenance [GO:0006276]; response to radiation [GO:0009314]	telomere capping [GO:0016233]	DNA replication, synthesis of RNA primer [GO:0006269]; DNA replication initiation [GO:0006270]; plasmid maintenance [GO:0006276]; response to radiation [GO:0009314]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	pre-primosome complex [GO:1990099]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]	identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]
d2i0ua__d1u4ja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d2i0xa1_d1zpwx1__1			Euryarchaeota	Deinococcus-Thermus	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; defense response to virus [GO:0051607]; maintenance of CRISPR repeat elements [GO:0043571]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; defense response to virus [GO:0051607]; maintenance of CRISPR repeat elements [GO:0043571]	defense response to virus [GO:0051607]; maintenance of CRISPR repeat elements [GO:0043571]	defense response to virus [GO:0051607]; maintenance of CRISPR repeat elements [GO:0043571]			endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]
d2i0xa1_d4qr0b___1			Euryarchaeota	Firmicutes	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; defense response to virus [GO:0051607]; maintenance of CRISPR repeat elements [GO:0043571]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; defense response to virus [GO:0051607]; maintenance of CRISPR repeat elements [GO:0043571]	defense response to virus [GO:0051607]; maintenance of CRISPR repeat elements [GO:0043571]	defense response to virus [GO:0051607]; maintenance of CRISPR repeat elements [GO:0043571]			endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]
d2i14b2_d5huoc1__1			Euryarchaeota	Firmicutes	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]			metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2i14d2_d1qpnb2__1			Euryarchaeota	Actinobacteria	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2i14e1_d1qpnd1__1			Euryarchaeota	Actinobacteria	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2i14e2_d1qpqe2__1			Euryarchaeota	Actinobacteria	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2i1ba__d1jt3b1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2i1na1_d1qava___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density, intracellular component [GO:0099092]; ionotropic glutamate receptor binding [GO:0035255]; kinase binding [GO:0019900]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein phosphatase binding [GO:0019903]; structural constituent of postsynaptic density [GO:0098919]; ubiquitin protein ligase binding [GO:0031625]; cell-cell adhesion [GO:0098609]; establishment of planar polarity [GO:0001736]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; MAPK cascade [GO:0000165]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of protein tyrosine kinase activity [GO:0061098]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of NMDA receptor activity [GO:2000310]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystrophin-associated glycoprotein complex [GO:0016010]; neuromuscular junction [GO:0031594]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; calmodulin binding [GO:0005516]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; PDZ domain binding [GO:0030165]; structural molecule activity [GO:0005198]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; neuromuscular junction development [GO:0007528]; regulation of heart rate [GO:0002027]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of vasoconstriction by circulating norepinephrine [GO:0003117]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; ventricular cardiac muscle cell action potential [GO:0086005]	cell-cell adhesion [GO:0098609]; establishment of planar polarity [GO:0001736]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; MAPK cascade [GO:0000165]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of protein tyrosine kinase activity [GO:0061098]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of NMDA receptor activity [GO:2000310]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]	negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; neuromuscular junction development [GO:0007528]; regulation of heart rate [GO:0002027]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of vasoconstriction by circulating norepinephrine [GO:0003117]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; ventricular cardiac muscle cell action potential [GO:0086005]	AMPA glutamate receptor complex [GO:0032281]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density, intracellular component [GO:0099092]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystrophin-associated glycoprotein complex [GO:0016010]; neuromuscular junction [GO:0031594]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]	ionotropic glutamate receptor binding [GO:0035255]; kinase binding [GO:0019900]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein phosphatase binding [GO:0019903]; structural constituent of postsynaptic density [GO:0098919]; ubiquitin protein ligase binding [GO:0031625]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; calmodulin binding [GO:0005516]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; PDZ domain binding [GO:0030165]; structural molecule activity [GO:0005198]
d2i1nb1_d4mpaa1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density, intracellular component [GO:0099092]; ionotropic glutamate receptor binding [GO:0035255]; kinase binding [GO:0019900]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein phosphatase binding [GO:0019903]; structural constituent of postsynaptic density [GO:0098919]; ubiquitin protein ligase binding [GO:0031625]; cell-cell adhesion [GO:0098609]; establishment of planar polarity [GO:0001736]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; MAPK cascade [GO:0000165]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of protein tyrosine kinase activity [GO:0061098]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of NMDA receptor activity [GO:2000310]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]; beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	cell-cell adhesion [GO:0098609]; establishment of planar polarity [GO:0001736]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; MAPK cascade [GO:0000165]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of protein tyrosine kinase activity [GO:0061098]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of NMDA receptor activity [GO:2000310]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]	actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein-containing complex assembly [GO:0065003]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	AMPA glutamate receptor complex [GO:0032281]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density, intracellular component [GO:0099092]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]	ionotropic glutamate receptor binding [GO:0035255]; kinase binding [GO:0019900]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein phosphatase binding [GO:0019903]; structural constituent of postsynaptic density [GO:0098919]; ubiquitin protein ligase binding [GO:0031625]	beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]
d2i1oa1_d1qpqb2__1			Euryarchaeota	Actinobacteria	metal ion binding [GO:0046872]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nucleotide binding [GO:0000166]; NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nucleotide binding [GO:0000166]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2i1oa2_d5hula2__1			Euryarchaeota	Firmicutes	metal ion binding [GO:0046872]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nucleotide binding [GO:0000166]; NAD biosynthetic process [GO:0009435]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]			metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nucleotide binding [GO:0000166]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2i24n1_d1zvsb___1	Metazoa	Metazoa	Chordata	Chordata	B cell receptor complex [GO:0019815]; B cell receptor signaling pathway [GO:0050853]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor complex [GO:0019815]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2i25n1_d4j4pb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2i25o1_d4gmtm2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d2i26l__d253la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2i26n1_d4xrcl1__1	Metazoa		Chordata	Negarnaviricota	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d2i26o2_d3gmnb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2i26p2_d2ak4d1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2i26p2_d5ibtl2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d2i2pb1_d1xnrb___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2i2pc1_d2zkqc1__1												
d2i2pe1_d2f1dl2__1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]		histidine biosynthetic process [GO:0000105]		chloroplast [GO:0009507]		imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2i2ph1_d2b64h1__1												
d2i2pj1_d2uxcj1__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2i2pk1_d1yi2n1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2i2po1_d2hgpr1__1												
d2i2pq1_d4h02c1__1				Apicomplexa		cytosol [GO:0005829]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; tRNA binding [GO:0000049]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; lysyl-tRNA aminoacylation [GO:0006430]		diadenosine tetraphosphate biosynthetic process [GO:0015966]; lysyl-tRNA aminoacylation [GO:0006430]		cytosol [GO:0005829]		ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; tRNA binding [GO:0000049]
d2i2ps1_d1qkfa___1				Deinococcus-Thermus		small ribosomal subunit [GO:0015935]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		small ribosomal subunit [GO:0015935]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2i2qa__d2l72a___1	Fungi		Ascomycota	Apicomplexa	actin cortical patch [GO:0030479]; actomyosin contractile ring [GO:0005826]; cell division site [GO:0032153]; cell tip [GO:0051286]; medial cortex [GO:0031097]; nuclear matrix [GO:0016363]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; actin filament debranching [GO:0071846]; actin filament depolymerization [GO:0030042]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; mitotic actomyosin contractile ring assembly [GO:1903475]; negative regulation of actin filament binding [GO:1904530]	actin cytoskeleton [GO:0015629]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]	actin filament debranching [GO:0071846]; actin filament depolymerization [GO:0030042]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; mitotic actomyosin contractile ring assembly [GO:1903475]; negative regulation of actin filament binding [GO:1904530]	actin filament depolymerization [GO:0030042]	actin cortical patch [GO:0030479]; actomyosin contractile ring [GO:0005826]; cell division site [GO:0032153]; cell tip [GO:0051286]; medial cortex [GO:0031097]; nuclear matrix [GO:0016363]	actin cytoskeleton [GO:0015629]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]	actin binding [GO:0003779]
d2i2td1_d2zjrb1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2i2tg1_d1q82g1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2i2ts1_d2zjpp1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2i2tt1_d1k8an___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2i2ui1_d2vhpe1__1												
d2i2ui1_d3wu3e___1												
d2i2uq1_d1lyla1__1				Proteobacteria		cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]		lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]		cytosol [GO:0005829]; membrane [GO:0016020]		ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]
d2i2vf1_d2zjrd1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2i2vg2_d1xbpe2__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2i2vp1_d2zjpm1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2i2vw1_d1v8qd___1				Deinococcus-Thermus		ribosome [GO:0005840]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		structural constituent of ribosome [GO:0003735]
d2i2wa__d2cxsb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]; lipopolysaccharide core region biosynthetic process [GO:0009244]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]; lipopolysaccharide core region biosynthetic process [GO:0009244]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d2i2wc__d1jxaa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]; lipopolysaccharide core region biosynthetic process [GO:0009244]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]
d2i2za2_d5iixa3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2i30a2_d3uiva2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2i32a1_d2z3fe1__1	Metazoa	Fungi	Chordata	Ascomycota	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; DNA repair [GO:0006281]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; muscle cell differentiation [GO:0042692]; negative regulation of chromatin silencing [GO:0031936]; nucleosome assembly [GO:0006334]; osteoblast differentiation [GO:0001649]	nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; histone binding [GO:0042393]; chromatin assembly [GO:0031497]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]	DNA repair [GO:0006281]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; muscle cell differentiation [GO:0042692]; negative regulation of chromatin silencing [GO:0031936]; nucleosome assembly [GO:0006334]; osteoblast differentiation [GO:0001649]	chromatin assembly [GO:0031497]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; histone binding [GO:0042393]	histone binding [GO:0042393]
d2i3va__d4nf0d___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; C4-dicarboxylate transport [GO:0015740]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	C4-dicarboxylate transport [GO:0015740]; transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d2i3vd__d3bftb___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2i3wa__d1hsja2__1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d2i3wb__d3fvgb___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2i3ya__d1eogb2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; selenium binding [GO:0008430]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; lipid metabolic process [GO:0006629]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; lipid metabolic process [GO:0006629]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; selenium binding [GO:0008430]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2i42a__d1q1ma___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	pathogenesis [GO:0009405]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	extracellular region [GO:0005576]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2i42a__d3mmja___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	protein tyrosine phosphatase activity [GO:0004725]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]		protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d2i47b__d1lnae___1	Metazoa		Chordata	Firmicutes	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]		actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d2i47c__d2wo8a___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d2i47c__d3l0tb___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d2i47d__d1zxcb___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d2i48a__d4h0wa1__1		Metazoa	Cyanobacteria	Chordata	plasma membrane [GO:0005886]; ion transport [GO:0006811]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	ion transport [GO:0006811]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d2i4db__d2er7e___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2i4qa1_d3uhlc___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2i4qa1_d5p0ya___1	Metazoa	Fungi	Chordata	Ascomycota	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]
d2i4qb1_d3ufnb___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2i4ua__d5p1oa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2i4wa__d5v8vb___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d2i4zb__d5k3la___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]; activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d2i54a__d2b1qa___1				Cyanobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]; GDP-mannose biosynthetic process [GO:0009298]	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]; sucrose biosynthetic process [GO:0005986]	GDP-mannose biosynthetic process [GO:0009298]	sucrose biosynthetic process [GO:0005986]	cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]	magnesium ion binding [GO:0000287]; sucrose-phosphate phosphatase activity [GO:0050307]
d2i54a__d2r8yh___1				Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]; GDP-mannose biosynthetic process [GO:0009298]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	GDP-mannose biosynthetic process [GO:0009298]	lipopolysaccharide biosynthetic process [GO:0009103]	cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d2i55a__d1wzcb2__1				Euryarchaeota	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]; GDP-mannose biosynthetic process [GO:0009298]	cytoplasm [GO:0005737]; mannosyl-3-phosphoglycerate phosphatase activity [GO:0050531]; metal ion binding [GO:0046872]; mannosylglycerate biosynthetic process [GO:0051479]	GDP-mannose biosynthetic process [GO:0009298]	mannosylglycerate biosynthetic process [GO:0051479]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]	mannosyl-3-phosphoglycerate phosphatase activity [GO:0050531]; metal ion binding [GO:0046872]
d2i55c__d1ek2b1__1		Metazoa		Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]; GDP-mannose biosynthetic process [GO:0009298]	cytosol [GO:0005829]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]	GDP-mannose biosynthetic process [GO:0009298]	cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; peroxisome [GO:0005777]	metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2i5yh1_d5mo9l2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	axon [GO:0030424]; axon terminus [GO:0043679]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; brain-derived neurotrophic factor binding [GO:0048403]; brain-derived neurotrophic factor-activated receptor activity [GO:0060175]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of phospholipase C activity [GO:0007202]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cellular response to amino acid stimulus [GO:0071230]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; circadian rhythm [GO:0007623]; feeding behavior [GO:0007631]; glutamate secretion [GO:0014047]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuronal action potential propagation [GO:0019227]; neurotrophin TRK receptor signaling pathway [GO:0048011]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system neuron development [GO:0048935]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; retinal rod cell development [GO:0046548]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trans-synaptic signaling by neuropeptide, modulating synaptic transmission [GO:0099551]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	activation of phospholipase C activity [GO:0007202]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cellular response to amino acid stimulus [GO:0071230]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; circadian rhythm [GO:0007623]; feeding behavior [GO:0007631]; glutamate secretion [GO:0014047]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neuronal action potential propagation [GO:0019227]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neurotrophin TRK receptor signaling pathway [GO:0048011]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system neuron development [GO:0048935]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; retinal rod cell development [GO:0046548]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trans-synaptic signaling by neuropeptide, modulating synaptic transmission [GO:0099551]; vasculogenesis [GO:0001570]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	axon [GO:0030424]; axon terminus [GO:0043679]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; brain-derived neurotrophic factor-activated receptor activity [GO:0060175]; brain-derived neurotrophic factor binding [GO:0048403]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2i5yl1_d2cdfa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2i5yq2_d2hlff2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2i5yr1_d3mlvm2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	structural molecule activity [GO:0005198]
d2i5zo__d5b3mo___1			Spirochaetes		cell outer membrane [GO:0009279]; membrane [GO:0016020]; modulation by symbiont of microbe-associated molecular pattern-induced host innate immune response [GO:0052157]		modulation by symbiont of microbe-associated molecular pattern-induced host innate immune response [GO:0052157]		cell outer membrane [GO:0009279]; membrane [GO:0016020]			
d2i60h1_d5mhrg2__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d2i60l1_d4d0ba1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]	structural molecule activity [GO:0005198]	protein homodimerization activity [GO:0042803]
d2i60q2_d4cada1__1				Euryarchaeota	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]; CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	structural molecule activity [GO:0005198]	cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]
d2i60r1_d2dtsb2__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2i60r1_d3levl1__1				Deinococcus-Thermus	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]; transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]
d2i62d__d1n7ja___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nicotinamide N-methyltransferase activity [GO:0008112]; animal organ regeneration [GO:0031100]; methylation [GO:0032259]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	animal organ regeneration [GO:0031100]; methylation [GO:0032259]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	nicotinamide N-methyltransferase activity [GO:0008112]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d2i62d__d4uoeb___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nicotinamide N-methyltransferase activity [GO:0008112]; animal organ regeneration [GO:0031100]; methylation [GO:0032259]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	animal organ regeneration [GO:0031100]; methylation [GO:0032259]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	nicotinamide N-methyltransferase activity [GO:0008112]	spermidine synthase activity [GO:0004766]
d2i65b__d1r12b___1	Metazoa	Metazoa	Chordata	Mollusca	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	cytoplasmic vesicle [GO:0031410]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]
d2i6ab__d4c5kd1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; AMP salvage [GO:0044209]; dATP biosynthetic process [GO:0006175]; purine ribonucleoside salvage [GO:0006166]; purine-containing compound salvage [GO:0043101]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	ATP binding [GO:0005524]; phosphomethylpyrimidine kinase activity [GO:0008972]; thiamine biosynthetic process [GO:0009228]	AMP salvage [GO:0044209]; dATP biosynthetic process [GO:0006175]; purine-containing compound salvage [GO:0043101]; purine ribonucleoside salvage [GO:0006166]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	thiamine biosynthetic process [GO:0009228]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; phosphomethylpyrimidine kinase activity [GO:0008972]
d2i6fc__d2msla___1			Proteobacteria	Proteobacteria	phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]				
d2i6ub1_d3m4ja1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]
d2i6uc1_d2fzga2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2i74b__d5ofxa___1	Metazoa		Chordata	Proteobacteria	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]; glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2i78a2_d1cuza___1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	cutinase activity [GO:0050525]
d2i78b2_d3pi6c1__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	hydrolase activity [GO:0016787]
d2i78c2_d3fvra___1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	acetylesterase activity [GO:0008126]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	acetylesterase activity [GO:0008126]
d2i78d2_d5alka2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2i79a__d1pu9a___1		Fungi	Firmicutes	Ascomycota	N-acetyltransferase activity [GO:0008080]	CENP-A containing nucleosome [GO:0043505]; nuclear nucleosome [GO:0000788]; nucleus [GO:0005634]; replication fork protection complex [GO:0031298]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin assembly or disassembly [GO:0006333]; global genome nucleotide-excision repair [GO:0070911]; rRNA transcription [GO:0009303]; sexual sporulation resulting in formation of a cellular spore [GO:0043935]		chromatin assembly or disassembly [GO:0006333]; global genome nucleotide-excision repair [GO:0070911]; rRNA transcription [GO:0009303]; sexual sporulation resulting in formation of a cellular spore [GO:0043935]		CENP-A containing nucleosome [GO:0043505]; nuclear nucleosome [GO:0000788]; nucleus [GO:0005634]; replication fork protection complex [GO:0031298]	N-acetyltransferase activity [GO:0008080]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2i79a__d4bbhb1__1			Firmicutes	Apicomplexa	N-acetyltransferase activity [GO:0008080]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]		N-terminal protein myristoylation [GO:0006499]			N-acetyltransferase activity [GO:0008080]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d2i79e__d1s3zb___1			Firmicutes	Proteobacteria	N-acetyltransferase activity [GO:0008080]	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]; protein homodimerization activity [GO:0042803]; acetyl-CoA metabolic process [GO:0006084]; histone acetylation [GO:0016573]; response to antibiotic [GO:0046677]		acetyl-CoA metabolic process [GO:0006084]; histone acetylation [GO:0016573]; response to antibiotic [GO:0046677]			N-acetyltransferase activity [GO:0008080]	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]; protein homodimerization activity [GO:0042803]
d2i7cb__d2bm8i___1			Apicomplexa	Actinobacteria	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]		spermidine synthase activity [GO:0004766]	methyltransferase activity [GO:0008168]
d2i7fa__d2ibze1__1		Fungi	Proteobacteria	Ascomycota	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	
d2i7fb__d3foub___1			Proteobacteria	Deinococcus-Thermus	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]				integral component of membrane [GO:0016021]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]
d2i7ka1_d5fe0a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone binding [GO:0042393]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell cycle [GO:0007049]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; Wnt signaling pathway [GO:0016055]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cell cycle [GO:0007049]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; Wnt signaling pathway [GO:0016055]	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]	histone binding [GO:0042393]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]
d2i7oa__d2j5wa5__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	oxidation-reduction process [GO:0055114]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d2i7pa1_d2zhca1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nucleus [GO:0005634]; acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]; coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	identical protein binding [GO:0042802]; plasmid partitioning [GO:0030541]	coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	plasmid partitioning [GO:0030541]	cytosol [GO:0005829]; nucleus [GO:0005634]		acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]	identical protein binding [GO:0042802]
d2i7pa1_d3smpb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]; coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	cell periphery [GO:0071944]; clathrin coat [GO:0030118]; cytosol [GO:0005829]; nucleus [GO:0005634]; recycling endosome [GO:0055037]; acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; coenzyme A biosynthetic process [GO:0015937]; coenzyme biosynthetic process [GO:0009108]	coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	coenzyme A biosynthetic process [GO:0015937]; coenzyme biosynthetic process [GO:0009108]	cytosol [GO:0005829]; nucleus [GO:0005634]	cell periphery [GO:0071944]; clathrin coat [GO:0030118]; cytosol [GO:0005829]; nucleus [GO:0005634]; recycling endosome [GO:0055037]	acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]	acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]
d2i7pb1_d3o4wa1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; nucleus [GO:0005634]; acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]; coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cytosol [GO:0005829]; nucleus [GO:0005634]	cell [GO:0005623]	acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]
d2i7pc1_d4fpba2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]; coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cytosol [GO:0005829]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d2i7sc__d4n2ca1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; chromatin-mediated maintenance of transcription [GO:0048096]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]	oxidation-reduction process [GO:0055114]	cellular response to leukemia inhibitory factor [GO:1990830]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin organization [GO:0006325]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]
d2i7sd__d1npjb2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2i80b1_d1ehia1__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2i81b__d1guhd2__1		Metazoa	Apicomplexa	Chordata	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	peroxiredoxin activity [GO:0051920]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2i81b__d5d9xa1__1		Viridiplantae	Apicomplexa	Streptophyta	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; ascorbate glutathione cycle [GO:0033355]; cellular oxidant detoxification [GO:0098869]; protein glutathionylation [GO:0010731]	cell redox homeostasis [GO:0045454]	ascorbate glutathione cycle [GO:0033355]; cellular oxidant detoxification [GO:0098869]; protein glutathionylation [GO:0010731]	cell [GO:0005623]	cytosol [GO:0005829]	peroxiredoxin activity [GO:0051920]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]
d2i81e__d2caib2__1		Metazoa	Apicomplexa	Platyhelminthes	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]		peroxiredoxin activity [GO:0051920]	glutathione transferase activity [GO:0004364]
d2i83a__d4mrea1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; collagen binding [GO:0005518]; hyaluronic acid binding [GO:0005540]; transmembrane signaling receptor activity [GO:0004888]; cartilage development [GO:0051216]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cellular response to fibroblast growth factor stimulus [GO:0044344]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte migration [GO:0050900]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; wound healing, spreading of cells [GO:0044319]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	cartilage development [GO:0051216]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte migration [GO:0050900]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; wound healing, spreading of cells [GO:0044319]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	collagen binding [GO:0005518]; hyaluronic acid binding [GO:0005540]; transmembrane signaling receptor activity [GO:0004888]	epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d2i89a__d1m20a___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2i89c__d1wdba___1	Metazoa		Chordata		integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]				integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]		electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d2i8ca1_d1kjjb2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d2i8cb1_d5oskf1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d2i8ua__d3shdf___1			Proteobacteria	Proteobacteria	GDP-mannose mannosyl hydrolase activity [GO:0008727]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]					GDP-mannose mannosyl hydrolase activity [GO:0008727]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]
d2i94a__d2zn9a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; calcium ion binding [GO:0005509]; phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]
d2i96a__d4b8na___1	Metazoa		Chordata		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; cytochrome-c oxidase activity [GO:0004129]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; L-ascorbic acid metabolic process [GO:0019852]; response to cadmium ion [GO:0046686]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	L-ascorbic acid metabolic process [GO:0019852]; response to cadmium ion [GO:0046686]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]		cytochrome-c oxidase activity [GO:0004129]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2i9ea__d3pwab___1	Metazoa		Arthropoda	Apicomplexa	triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]			triose-phosphate isomerase activity [GO:0004807]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]
d2i9eb1_d1sw3b___1	Metazoa	Metazoa	Arthropoda	Chordata	triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]		cytosol [GO:0005829]	triose-phosphate isomerase activity [GO:0004807]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]
d2i9eb1_d5csrd1__1	Metazoa		Arthropoda	Euryarchaeota	triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2i9ga1_d4iqta1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2i9lc1_d3sobl2__1		Metazoa		Chordata	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	caveola [GO:0005901]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]; Wnt-Frizzled-LRP5/6 complex [GO:1990851]; apolipoprotein binding [GO:0034185]; coreceptor activity involved in canonical Wnt signaling pathway [GO:1904928]; coreceptor activity involved in Wnt signaling pathway [GO:0071936]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; kinase inhibitor activity [GO:0019210]; low-density lipoprotein particle receptor activity [GO:0005041]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; toxin transmembrane transporter activity [GO:0019534]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; anterior/posterior pattern specification [GO:0009952]; axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; gastrulation with mouth forming second [GO:0001702]; midbrain development [GO:0030901]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; roof of mouth development [GO:0060021]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	anterior/posterior pattern specification [GO:0009952]; axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; gastrulation with mouth forming second [GO:0001702]; midbrain development [GO:0030901]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; roof of mouth development [GO:0060021]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	caveola [GO:0005901]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202]; Wnt-Frizzled-LRP5/6 complex [GO:1990851]; Wnt signalosome [GO:1990909]		apolipoprotein binding [GO:0034185]; coreceptor activity involved in canonical Wnt signaling pathway [GO:1904928]; coreceptor activity involved in Wnt signaling pathway [GO:0071936]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; kinase inhibitor activity [GO:0019210]; low-density lipoprotein particle receptor activity [GO:0005041]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; toxin transmembrane transporter activity [GO:0019534]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]
d2i9lc2_d3kpse1__1		Metazoa		Chordata	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2i9lc2_d4z7ug2__1		Viridiplantae		Streptophyta	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	nutrient reservoir activity [GO:0045735]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]			nutrient reservoir activity [GO:0045735]
d2i9le1_d1nd0a2__1		Metazoa		Chordata	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	metal ion binding [GO:0046872]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]			metal ion binding [GO:0046872]
d2i9le1_d3nidf1__1		Metazoa		Chordata	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2i9le2_d1vpol2__1					integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]			
d2i9le2_d2gjjb2__1					integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]			
d2i9lg2_d1um6h2__1		Metazoa		Chordata	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]			
d2i9ta1_d1fsta___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]
d2i9ta1_d1nfkb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2ia5h2_d2hjva___1				Firmicutes	ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; deoxynucleotide 3'-phosphatase activity [GO:0047846]; DNA repair [GO:0006281]; viral process [GO:0016032]	cytosol [GO:0005829]; 3'-5' RNA helicase activity [GO:0034458]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; RNA strand annealing activity [GO:0033592]; ribosomal large subunit assembly [GO:0000027]	DNA repair [GO:0006281]; viral process [GO:0016032]	ribosomal large subunit assembly [GO:0000027]		cytosol [GO:0005829]	ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; deoxynucleotide 3'-phosphatase activity [GO:0047846]	3'-5' RNA helicase activity [GO:0034458]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; RNA strand annealing activity [GO:0033592]
d2ia5k2_d4bfta___1				Actinobacteria	ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; deoxynucleotide 3'-phosphatase activity [GO:0047846]; DNA repair [GO:0006281]; viral process [GO:0016032]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	DNA repair [GO:0006281]; viral process [GO:0016032]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; deoxynucleotide 3'-phosphatase activity [GO:0047846]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d2ia6a2_d2r8ja1__1		Fungi	Crenarchaeota	Ascomycota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d2iaac__d1bqka___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; amine dehydrogenase activity [GO:0030058]; aralkylamine dehydrogenase (azurin) activity [GO:0030059]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	amine dehydrogenase activity [GO:0030058]; aralkylamine dehydrogenase (azurin) activity [GO:0030059]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2iaac__d2xwza2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; amine dehydrogenase activity [GO:0030058]; aralkylamine dehydrogenase (azurin) activity [GO:0030059]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		amine dehydrogenase activity [GO:0030058]; aralkylamine dehydrogenase (azurin) activity [GO:0030059]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2iada2_d1s7xa2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2iadb1_d4ezma1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d2iaja2_d3o3fa___1				Thermotogae	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]; ribonuclease H2 complex [GO:0032299]; manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; mismatch repair [GO:0006298]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA replication, removal of RNA primer [GO:0043137]; mismatch repair [GO:0006298]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; ribonuclease H2 complex [GO:0032299]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d2iala1_d3mrhb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2iala1_d3sknf1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2ialb1_d1t1za1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ialb1_d5jhll1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2ialb2_d1ls0b5__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2iald1_d3upra2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2iama1_d3levh1__1	Metazoa		Chordata	Deinococcus-Thermus	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]; transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytoplasm [GO:0005737]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]
d2iana1_d5d96b2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]; FAD binding [GO:0071949]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]; extracellular matrix assembly [GO:0085029]; negative regulation of macroautophagy [GO:0016242]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell redox homeostasis [GO:0045454]; extracellular matrix assembly [GO:0085029]; negative regulation of macroautophagy [GO:0016242]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; intercellular bridge [GO:0045171]; intracellular membrane-bounded organelle [GO:0043231]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	FAD binding [GO:0071949]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide isomerase activity [GO:0003756]
d2iane1_d5cipb2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2iane2_d1hxmg2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	transmembrane signaling receptor activity [GO:0004888]
d2ianf1_d1blnb2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2ianf1_d5vzxl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2ianj1_d1fvcc___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2ianj2_d5wkie1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2iank2_d1e27a2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2iano1_d2mpah2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2iano1_d5jore1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2iano2_d1mhpl2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]
d2iano2_d3auvf2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2ianq1_d1pg7z2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ians2_d3tvmg1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2iapa__d2dsob2__1	Metazoa		Mollusca	Firmicutes	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]				cytoplasm [GO:0005737]	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2iapa__d5gx2a___1	Metazoa	Metazoa	Mollusca	Arthropoda	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	metal ion binding [GO:0046872]					calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	metal ion binding [GO:0046872]
d2iasa__d2iara___1	Metazoa	Metazoa	Mollusca	Mollusca	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]					calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]
d2iata__d2dsof2__1	Metazoa		Mollusca	Firmicutes	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]				cytoplasm [GO:0005737]	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2ib1a__d2n97b___1	Metazoa	Metazoa	Chordata	Chordata	cell body membrane [GO:0044298]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection membrane [GO:0032589]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; death receptor activity [GO:0005035]; nerve growth factor binding [GO:0048406]; neurotrophin p75 receptor binding [GO:0005166]; apoptotic process [GO:0006915]; brain development [GO:0007420]; in utero embryonic development [GO:0001701]; positive regulation of cell death [GO:0010942]; Rho protein signal transduction [GO:0007266]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endosome [GO:0005768]; extracellular region [GO:0005576]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; calmodulin binding [GO:0005516]; coreceptor activity [GO:0015026]; death receptor activity [GO:0005035]; nerve growth factor binding [GO:0048406]; neurotrophin binding [GO:0043121]; Rab GTPase binding [GO:0017137]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular glucose homeostasis [GO:0001678]; cellular response to amyloid-beta [GO:1904646]; circadian regulation of gene expression [GO:0032922]; glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of protein localization to nucleus [GO:1900182]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; Rho protein signal transduction [GO:0007266]	apoptotic process [GO:0006915]; brain development [GO:0007420]; in utero embryonic development [GO:0001701]; positive regulation of cell death [GO:0010942]; Rho protein signal transduction [GO:0007266]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular glucose homeostasis [GO:0001678]; cellular response to amyloid-beta [GO:1904646]; circadian regulation of gene expression [GO:0032922]; glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of protein localization to nucleus [GO:1900182]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; Rho protein signal transduction [GO:0007266]	cell body membrane [GO:0044298]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection membrane [GO:0032589]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endosome [GO:0005768]; extracellular region [GO:0005576]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; death receptor activity [GO:0005035]; nerve growth factor binding [GO:0048406]; neurotrophin p75 receptor binding [GO:0005166]	amyloid-beta binding [GO:0001540]; calmodulin binding [GO:0005516]; coreceptor activity [GO:0015026]; death receptor activity [GO:0005035]; nerve growth factor binding [GO:0048406]; neurotrophin binding [GO:0043121]; Rab GTPase binding [GO:0017137]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]
d2ibaa1_d1a8ra___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d2ibgb1_d2dbja1__1	Metazoa	Metazoa	Arthropoda	Chordata	cell surface [GO:0009986]; cytoneme [GO:0035230]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; hedgehog family protein binding [GO:0097108]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; patched binding [GO:0005113]; protein homodimerization activity [GO:0042803]; compound eye development [GO:0048749]; cuticle pattern formation [GO:0035017]; maintenance of protein location in extracellular region [GO:0071694]; segment specification [GO:0007379]; smoothened signaling pathway [GO:0007224]; wing disc pattern formation [GO:0035222]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; rhabdomere [GO:0016028]; ATP binding [GO:0005524]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; apoptotic cell clearance [GO:0043277]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; leukocyte migration [GO:0050900]; natural killer cell differentiation [GO:0001779]; negative regulation of cytokine production [GO:0001818]; negative regulation of leukocyte apoptotic process [GO:2000107]; negative regulation of lymphocyte activation [GO:0051250]; nervous system development [GO:0007399]; neutrophil clearance [GO:0097350]; phagocytosis [GO:0006909]; platelet activation [GO:0030168]; positive regulation of phagocytosis [GO:0050766]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; retina development in camera-type eye [GO:0060041]; secretion by cell [GO:0032940]; spermatogenesis [GO:0007283]; substrate adhesion-dependent cell spreading [GO:0034446]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vagina development [GO:0060068]	compound eye development [GO:0048749]; cuticle pattern formation [GO:0035017]; maintenance of protein location in extracellular region [GO:0071694]; segment specification [GO:0007379]; smoothened signaling pathway [GO:0007224]; wing disc pattern formation [GO:0035222]	apoptotic cell clearance [GO:0043277]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; leukocyte migration [GO:0050900]; natural killer cell differentiation [GO:0001779]; negative regulation of cytokine production [GO:0001818]; negative regulation of leukocyte apoptotic process [GO:2000107]; negative regulation of lymphocyte activation [GO:0051250]; nervous system development [GO:0007399]; neutrophil clearance [GO:0097350]; phagocytosis [GO:0006909]; platelet activation [GO:0030168]; positive regulation of phagocytosis [GO:0050766]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; retina development in camera-type eye [GO:0060041]; secretion by cell [GO:0032940]; spermatogenesis [GO:0007283]; substrate adhesion-dependent cell spreading [GO:0034446]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vagina development [GO:0060068]	cell surface [GO:0009986]; cytoneme [GO:0035230]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; rhabdomere [GO:0016028]	coreceptor activity [GO:0015026]; hedgehog family protein binding [GO:0097108]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; patched binding [GO:0005113]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2ibja__d3nerb___1	Metazoa	Metazoa	Arthropoda	Chordata	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2ibka1_d2r8jb1__1		Fungi	Crenarchaeota	Ascomycota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d2ibsd1_d5k0gb___1		Metazoa	Deinococcus-Thermus	Chordata	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	DNA restriction-modification system [GO:0009307]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d2ibta2_d1yf2a2__1			Deinococcus-Thermus	Euryarchaeota	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	DNA binding [GO:0003677]
d2ibtd1_d2bm8l___1			Deinococcus-Thermus	Actinobacteria	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	DNA restriction-modification system [GO:0009307]	lipid biosynthetic process [GO:0008610]			DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	methyltransferase activity [GO:0008168]
d2ibtd2_d1yf2a1__1			Deinococcus-Thermus	Euryarchaeota	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	DNA binding [GO:0003677]
d2ibxa1_d1uf2f2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]; RNA binding [GO:0003723]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]	host cell surface receptor binding [GO:0046789]	RNA binding [GO:0003723]
d2ibxc__d5thfc1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2ibza1_d1sqxb1__1	Fungi	Metazoa	Ascomycota	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d2ibzb1_d1hr6b2__1	Fungi	Fungi	Ascomycota	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d2ibzb2_d3l74n1__1	Fungi	Metazoa	Ascomycota	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d2ibzd1_d2pccd___1	Fungi	Fungi	Ascomycota	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2ibzx__d4l4jb2__1	Fungi	Metazoa	Ascomycota	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ibzy__d1zvya1__1	Fungi	Metazoa	Ascomycota	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2ic1a1_d5ezwa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; inflammatory response [GO:0006954]; L-cysteine catabolic process [GO:0019448]; lactation [GO:0007595]; oxidation-reduction process [GO:0055114]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; sulfur amino acid biosynthetic process [GO:0000097]; taurine biosynthetic process [GO:0042412]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	cysteine metabolic process [GO:0006534]; inflammatory response [GO:0006954]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; oxidation-reduction process [GO:0055114]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; sulfur amino acid biosynthetic process [GO:0000097]; taurine biosynthetic process [GO:0042412]	cysteine metabolic process [GO:0006534]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d2ic3a2_d4lsla2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2ic7a__d1krva___1			Firmicutes	Proteobacteria	maltose O-acetyltransferase activity [GO:0008925]	cytoplasm [GO:0005737]; galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]; lactose biosynthetic process [GO:0005989]		lactose biosynthetic process [GO:0005989]		cytoplasm [GO:0005737]	maltose O-acetyltransferase activity [GO:0008925]	galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]
d2ic7a__d1yp4d1__1		Viridiplantae	Firmicutes	Streptophyta	maltose O-acetyltransferase activity [GO:0008925]	amyloplast [GO:0009501]; chloroplast [GO:0009507]; ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]; glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]		glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]		amyloplast [GO:0009501]; chloroplast [GO:0009507]	maltose O-acetyltransferase activity [GO:0008925]	ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]
d2ic7b__d1xata___1			Firmicutes	Proteobacteria	maltose O-acetyltransferase activity [GO:0008925]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]			maltose O-acetyltransferase activity [GO:0008925]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d2ic7c__d1ocxb___1			Firmicutes	Proteobacteria	maltose O-acetyltransferase activity [GO:0008925]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; maltose O-acetyltransferase activity [GO:0008925]; protein homotrimerization [GO:0070207]		protein homotrimerization [GO:0070207]		cytosol [GO:0005829]	maltose O-acetyltransferase activity [GO:0008925]	identical protein binding [GO:0042802]; maltose O-acetyltransferase activity [GO:0008925]
d2icqa1_d1wplf___1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]
d2icqa2_d1nbud___1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]
d2icwa1_d2fl5l2__1		Metazoa	Tenericutes	Chordata								
d2icwa1_d3pwjb1__1		Metazoa	Tenericutes	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2icwb2_d4l3co1__1		Metazoa	Tenericutes	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2icwd1_d2qr0k2__1		Metazoa	Tenericutes	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2icwj1_d3eo1j1__1		Metazoa	Tenericutes	Chordata		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell development [GO:0048468]; cell-cell junction organization [GO:0045216]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; in utero embryonic development [GO:0001701]; inner ear development [GO:0048839]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]		activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell development [GO:0048468]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; inner ear development [GO:0048839]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]		cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]
d2icwj1_d5bk3l2__1			Tenericutes									
d2icya1_d3tiod___1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; pollen tube [GO:0090406]; UTP:glucose-1-phosphate uridylyltransferase activity [GO:0003983]; callose deposition in cell wall [GO:0052543]; cellular response to phosphate starvation [GO:0016036]; glycogen metabolic process [GO:0005977]; pollen development [GO:0009555]; sucrose metabolic process [GO:0005985]; UDP-glucose metabolic process [GO:0006011]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; protein homotrimerization [GO:0070207]	callose deposition in cell wall [GO:0052543]; cellular response to phosphate starvation [GO:0016036]; glycogen metabolic process [GO:0005977]; pollen development [GO:0009555]; sucrose metabolic process [GO:0005985]; UDP-glucose metabolic process [GO:0006011]	protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; pollen tube [GO:0090406]	cytosol [GO:0005829]	UTP:glucose-1-phosphate uridylyltransferase activity [GO:0003983]	identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d2icyb1_d1yp3a1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; pollen tube [GO:0090406]; UTP:glucose-1-phosphate uridylyltransferase activity [GO:0003983]; callose deposition in cell wall [GO:0052543]; cellular response to phosphate starvation [GO:0016036]; glycogen metabolic process [GO:0005977]; pollen development [GO:0009555]; sucrose metabolic process [GO:0005985]; UDP-glucose metabolic process [GO:0006011]	amyloplast [GO:0009501]; chloroplast [GO:0009507]; ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]; glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	callose deposition in cell wall [GO:0052543]; cellular response to phosphate starvation [GO:0016036]; glycogen metabolic process [GO:0005977]; pollen development [GO:0009555]; sucrose metabolic process [GO:0005985]; UDP-glucose metabolic process [GO:0006011]	glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; pollen tube [GO:0090406]	amyloplast [GO:0009501]; chloroplast [GO:0009507]	UTP:glucose-1-phosphate uridylyltransferase activity [GO:0003983]	ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]
d2id2a__d4l2og___1		Metazoa	Firmicutes	Chordata	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]
d2id2c__d2o2qd___1		Metazoa	Firmicutes	Chordata	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]
d2id2d__d5l2ob___1		Metazoa	Firmicutes	Chordata	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; androgen binding [GO:0005497]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; GTPase activator activity [GO:0005096]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; cellular aldehyde metabolic process [GO:0006081]; ethanol oxidation [GO:0006069]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; negative regulation of cold-induced thermogenesis [GO:0120163]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cellular aldehyde metabolic process [GO:0006081]; ethanol oxidation [GO:0006069]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; negative regulation of cold-induced thermogenesis [GO:0120163]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; androgen binding [GO:0005497]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; GTPase activator activity [GO:0005096]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]
d2id4a1_d4lk6b___1	Fungi		Ascomycota	Proteobacteria	fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	carbohydrate binding [GO:0030246]
d2idfa__d1tefa___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2idfb__d4a2ga2__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2idoc__d3bdpa1__1				Firmicutes	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA replication [GO:0006260]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA replication [GO:0006260]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]			DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d2idsa__d3fu8a3__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2idwa__d5lwsa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2ie3a__d1m8wa___1	Metazoa	Metazoa	Chordata	Chordata	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]	GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]
d2ie4a__d5ni6a3__1	Metazoa	Metazoa	Chordata	Chordata	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2ie4c1_d5xchb___1	Metazoa		Chordata		chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	cytosol [GO:0005829]; endosome [GO:0005768]; retromer complex [GO:0030904]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]	cytosol [GO:0005829]; endosome [GO:0005768]; retromer complex [GO:0030904]	GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]	
d2ie7a__d1hvda___1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; positive regulation of apoptotic process [GO:0043065]; protein homooligomerization [GO:0051260]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	axon terminus [GO:0043679]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; intercalated disc [GO:0014704]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; Z disc [GO:0030018]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; receptor tyrosine kinase binding [GO:0030971]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]
d2ieaa3_d1qgda3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	glycolytic process [GO:0006096]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d2ieda__d3g49a___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; lung development [GO:0030324]; steroid metabolic process [GO:0008202]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	lung development [GO:0030324]; steroid metabolic process [GO:0008202]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]
d2ieja__d1tnoa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]; protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]; protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	protein farnesylation [GO:0018343]; protein prenylation [GO:0018342]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; microtubule associated complex [GO:0005875]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	protein farnesyltransferase activity [GO:0004660]; zinc ion binding [GO:0008270]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d2iena__d5p3ca___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2ieob__d1mtbb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2iepa2_d1uz8l1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cell projection [GO:0042995]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; cochlea development [GO:0090102]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to muscle activity [GO:0014850]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cochlea development [GO:0090102]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to muscle activity [GO:0014850]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell junction [GO:0030054]; cell projection [GO:0042995]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2iepb1_d1ffnb1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cell projection [GO:0042995]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; cochlea development [GO:0090102]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to muscle activity [GO:0014850]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cochlea development [GO:0090102]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to muscle activity [GO:0014850]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell junction [GO:0030054]; cell projection [GO:0042995]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2iepb1_d4zsoa1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cell projection [GO:0042995]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; cochlea development [GO:0090102]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to muscle activity [GO:0014850]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; regulation of immune response [GO:0050776]	cochlea development [GO:0090102]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein autophosphorylation [GO:0046777]; receptor clustering [GO:0043113]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to muscle activity [GO:0014850]; retina development in camera-type eye [GO:0060041]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	regulation of immune response [GO:0050776]	cell junction [GO:0030054]; cell projection [GO:0042995]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; neuromuscular junction [GO:0031594]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	
d2ierb2_d3wu5d___1			Aquificae		metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]		lipid A biosynthetic process [GO:0009245]				metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]	
d2iesa1_d1nhja1__1			Aquificae	Proteobacteria	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	mismatch repair complex [GO:0032300]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]; mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]	lipid A biosynthetic process [GO:0009245]	mismatch repair [GO:0006298]; regulation of DNA recombination [GO:0000018]		mismatch repair complex [GO:0032300]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; mismatched DNA binding [GO:0030983]
d2if4a2_d2fbnb___1	Viridiplantae		Streptophyta	Apicomplexa	endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; calmodulin binding [GO:0005516]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; auxin-activated signaling pathway [GO:0009734]; leaf development [GO:0048366]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein dimerization activity [GO:0046983]; chaperone-mediated protein folding [GO:0061077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	auxin-activated signaling pathway [GO:0009734]; leaf development [GO:0048366]	chaperone-mediated protein folding [GO:0061077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	calmodulin binding [GO:0005516]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein dimerization activity [GO:0046983]
d2if9a2_d1rz9b___1					ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; hydrolase activity [GO:0016787]; DNA replication [GO:0006260]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; DNA replication [GO:0006260]; viral genome replication [GO:0019079]	DNA replication [GO:0006260]	DNA replication [GO:0006260]; viral genome replication [GO:0019079]			ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; hydrolase activity [GO:0016787]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d2if9b2_d1f08b___1					ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; hydrolase activity [GO:0016787]; DNA replication [GO:0006260]	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA replication [GO:0006260]	DNA replication [GO:0006260]	DNA replication [GO:0006260]		host cell nucleus [GO:0042025]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; hydrolase activity [GO:0016787]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]
d2ifcc__d3o8ja___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; 2-methylcitrate synthase activity [GO:0050440]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]; carbohydrate metabolic process [GO:0005975]; propionate metabolic process, methylcitrate cycle [GO:0019679]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; propionate metabolic process, methylcitrate cycle [GO:0019679]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]	2-methylcitrate synthase activity [GO:0050440]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]
d2iffh2_d2d31e1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ifga1_d1e0ob1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2ifgb2_d3c6se1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ifgb3_d1ozna___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; axonogenesis [GO:0007409]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	axonogenesis [GO:0007409]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative regulation of axon extension [GO:0030517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]	cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]	chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]
d2ifqb__d4mh3e___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d2ifva__d1whba1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; extrinsic component of endosome membrane [GO:0031313]; extrinsic component of plasma membrane [GO:0019897]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; cadherin binding [GO:0045296]; cysteine-type endopeptidase activity [GO:0004197]; SH3 domain binding [GO:0017124]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to nerve growth factor stimulus [GO:1990090]; endosome organization [GO:0007032]; mitotic cytokinesis [GO:0000281]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; Ras protein signal transduction [GO:0007265]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	cellular response to dexamethasone stimulus [GO:0071549]; cellular response to nerve growth factor stimulus [GO:1990090]; endosome organization [GO:0007032]; mitotic cytokinesis [GO:0000281]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; Ras protein signal transduction [GO:0007265]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; extrinsic component of endosome membrane [GO:0031313]; extrinsic component of plasma membrane [GO:0019897]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]	phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; cysteine-type endopeptidase activity [GO:0004197]; SH3 domain binding [GO:0017124]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]
d2ig2h2_d4l29u2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ig3b__d2zs1c___1		Metazoa	Proteobacteria	Annelida	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2ig9a2_d1kw6b1__1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]		aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]
d2ig9b1_d1kw8b2__1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]		aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]
d2ig9b1_d2zyqa1__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity [GO:0047071]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; aromatic compound catabolic process [GO:0019439]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; response to cholesterol [GO:0070723]		aromatic compound catabolic process [GO:0019439]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; response to cholesterol [GO:0070723]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity [GO:0047071]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]
d2ig9c2_d2ig9a1__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d2ig9d1_d5trxc2__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d2igad2_d2zyqb1__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity [GO:0047071]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; aromatic compound catabolic process [GO:0019439]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; response to cholesterol [GO:0070723]		aromatic compound catabolic process [GO:0019439]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; response to cholesterol [GO:0070723]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity [GO:0047071]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]
d2igca__d1gfka___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2igfl1_d2ckbd2__1	Metazoa	Metazoa	Annelida	Chordata	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2ignf2_d5mrlb2__1	Fungi	Metazoa	Basidiomycota	Chordata	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d2igoa2_d1ijha2__1	Fungi		Basidiomycota	Actinobacteria	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]		cholesterol metabolic process [GO:0008203]		extracellular region [GO:0005576]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]
d2igoc2_d1s3ea2__1	Fungi	Metazoa	Basidiomycota	Chordata	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d2igof2_d3qvpa2__1	Fungi	Fungi	Basidiomycota	Ascomycota	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	extracellular region [GO:0005576]; flavin adenine dinucleotide binding [GO:0050660]; glucose oxidase activity [GO:0046562]				extracellular region [GO:0005576]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	flavin adenine dinucleotide binding [GO:0050660]; glucose oxidase activity [GO:0046562]
d2igog2_d2byba2__1	Fungi	Metazoa	Basidiomycota	Chordata	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d2ih1a2_d6azzb1__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2ih1b1_d1bvlc1__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2ih1b2_d1ktrl___1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2ih2a1_d4blva___1			Deinococcus-Thermus	Proteobacteria	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	cytosol [GO:0005829]; 23S rRNA (adenine(2030)-N(6))-methyltransferase activity [GO:0036307]; RNA binding [GO:0003723]; rRNA (adenine-N6-)-methyltransferase activity [GO:0008988]; carbon utilization [GO:0015976]; rRNA base methylation [GO:0070475]	DNA restriction-modification system [GO:0009307]	carbon utilization [GO:0015976]; rRNA base methylation [GO:0070475]		cytosol [GO:0005829]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	23S rRNA (adenine(2030)-N(6))-methyltransferase activity [GO:0036307]; RNA binding [GO:0003723]; rRNA (adenine-N6-)-methyltransferase activity [GO:0008988]
d2ih3a2_d3auvd2__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2ih4a1_d5p9ra___1		Metazoa	Deinococcus-Thermus	Chordata	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	DNA restriction-modification system [GO:0009307]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d2ih8a3_d3sbrb2__1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	extraorganismal space [GO:0043245]	membrane [GO:0016020]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d2ih8b2_d1azrb___1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	oxidation-reduction process [GO:0055114]	extraorganismal space [GO:0043245]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2ih9a1_d1bxaa___1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		extraorganismal space [GO:0043245]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2ih9a2_d4kntb1__1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	nitrogen compound metabolic process [GO:0006807]	extraorganismal space [GO:0043245]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ih9b1_d2dysb1__1	Fungi	Metazoa	Ascomycota	Chordata	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	ATP synthesis coupled electron transport [GO:0042773]	extraorganismal space [GO:0043245]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2ih9b2_d4knue2__1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	nitrogen compound metabolic process [GO:0006807]	extraorganismal space [GO:0043245]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ih9b3_d2jfcc1__1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	nitrogen compound metabolic process [GO:0006807]	extraorganismal space [GO:0043245]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ihda__d2jm5a1__1	Metazoa	Metazoa	Chordata	Chordata	dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; neuronal cell body membrane [GO:0032809]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; synapse [GO:0045202]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of dopamine receptor signaling pathway [GO:0060159]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of dopamine receptor signaling pathway [GO:0060159]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; neuronal cell body membrane [GO:0032809]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; synapse [GO:0045202]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]
d2ihma1_d4qzca1__1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; B cell differentiation [GO:0030183]; base-excision repair [GO:0006284]; DNA recombination [GO:0006310]; double-strand break repair via nonhomologous end joining [GO:0006303]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	base-excision repair [GO:0006284]; B cell differentiation [GO:0030183]; DNA recombination [GO:0006310]; double-strand break repair via nonhomologous end joining [GO:0006303]; somatic hypermutation of immunoglobulin genes [GO:0016446]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2ihua3_d6bd9b1__1		Fungi	Actinobacteria	Ascomycota	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2ihub1_d1pyda3__1		Fungi	Actinobacteria	Ascomycota	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2ihuc3_d4k9nc3__1			Actinobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2ihud1_d2c42b1__1			Actinobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]		electron transport chain [GO:0022900]		cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d2ihud2_d5d7nf___1		Metazoa	Actinobacteria	Chordata	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d2ihva3_d5hyva1__1		Fungi	Actinobacteria	Ascomycota	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]					magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d2ihvb1_d1hzzc___1			Actinobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	NAD binding [GO:0051287]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]; NADPH regeneration [GO:0006740]		NADPH regeneration [GO:0006740]			magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]
d2ihvc1_d1mczo2__1			Actinobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2ihvd1_d5d7na___1		Metazoa	Actinobacteria	Chordata	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d2ihvd2_d2djia2__1			Actinobacteria	Firmicutes	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d2ihvd3_d1zpdf3__1			Actinobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2ihvd3_d2c31a2__1			Actinobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]		oxalate catabolic process [GO:0033611]			magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d2ihwc__d4n72b___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	pyruvate dehydrogenase complex [GO:0045254]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]
d2ihwd__d3maec___1	Metazoa		Chordata		cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]				cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]		acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	
d2ihwe__d4epha1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]		fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	carnitine O-palmitoyltransferase activity [GO:0004095]
d2ii3b__d3u9fr___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]		acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d2ii3h__d2h3ub1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]		carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	carnitine O-acetyltransferase activity [GO:0004092]
d2ii3h__d2h4tb3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]		fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	carnitine O-palmitoyltransferase activity [GO:0004095]
d2ii4c__d1t7oa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]		carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	carnitine O-acetyltransferase activity [GO:0004092]
d2ii4e__d3u9fi___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]		acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d2ii4h__d4ep9a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]		fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	carnitine O-palmitoyltransferase activity [GO:0004095]
d2ii5b__d1nm8a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; protein targeting to peroxisome [GO:0006625]		carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; protein targeting to peroxisome [GO:0006625]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	carnitine O-acetyltransferase activity [GO:0004092]
d2ii5c__d1xmdb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-octanoyltransferase activity [GO:0008458]; carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; response to drug [GO:0042493]		carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	carnitine O-octanoyltransferase activity [GO:0008458]
d2ii5e__d3u9fo___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]		acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d2ii5g__d3u9fh___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]		acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	chloramphenicol O-acetyltransferase activity [GO:0008811]
d2iida2_d1o5wd2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	integral component of membrane [GO:0016021]; mitochondrial outer membrane [GO:0005741]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; serotonin binding [GO:0051378]; catecholamine catabolic process [GO:0042424]; neurotransmitter catabolic process [GO:0042135]; phenylethylamine metabolic process [GO:0042443]; serotonin metabolic process [GO:0042428]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	catecholamine catabolic process [GO:0042424]; neurotransmitter catabolic process [GO:0042135]; phenylethylamine metabolic process [GO:0042443]; serotonin metabolic process [GO:0042428]	extracellular region [GO:0005576]	integral component of membrane [GO:0016021]; mitochondrial outer membrane [GO:0005741]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]	flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; serotonin binding [GO:0051378]
d2iikb2_d2rjtb2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; specific granule lumen [GO:0035580]; acetate CoA-transferase activity [GO:0008775]; acetyl-CoA C-acyltransferase activity [GO:0003988]; palmitoyl-CoA oxidase activity [GO:0016401]; alpha-linolenic acid metabolic process [GO:0036109]; bile acid metabolic process [GO:0008206]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; neutrophil degranulation [GO:0043312]; phenylacetate catabolic process [GO:0010124]; protein targeting to peroxisome [GO:0006625]; very long-chain fatty acid metabolic process [GO:0000038]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	alpha-linolenic acid metabolic process [GO:0036109]; bile acid metabolic process [GO:0008206]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; neutrophil degranulation [GO:0043312]; phenylacetate catabolic process [GO:0010124]; protein targeting to peroxisome [GO:0006625]; very long-chain fatty acid metabolic process [GO:0000038]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; specific granule lumen [GO:0035580]		acetate CoA-transferase activity [GO:0008775]; acetyl-CoA C-acyltransferase activity [GO:0003988]; palmitoyl-CoA oxidase activity [GO:0016401]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d2iita2_d3dyia___1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	carboxylic ester hydrolase activity [GO:0052689]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	carboxylic ester hydrolase activity [GO:0052689]
d2iiva2_d1jjib___1	Metazoa		Chordata	Euryarchaeota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	hydrolase activity [GO:0016787]
d2ij0c1_d4p9hl2__1			Firmicutes		extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	pathogenesis [GO:0009405]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	toxin activity [GO:0090729]	structural molecule activity [GO:0005198]
d2ij5a__d4uylb1__1		Fungi	Actinobacteria	Ascomycota	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; cellular response to drug [GO:0035690]; ergosterol biosynthetic process [GO:0006696]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	oxidation-reduction process [GO:0055114]	cellular response to drug [GO:0035690]; ergosterol biosynthetic process [GO:0006696]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]	drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d2ij5c__d3c6gb2__1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; vitamin D3 25-hydroxylase activity [GO:0030343]; calcitriol biosynthetic process from calciol [GO:0036378]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; response to cesium ion [GO:0010164]; response to ionizing radiation [GO:0010212]; vitamin D metabolic process [GO:0042359]; vitamin metabolic process [GO:0006766]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	calcitriol biosynthetic process from calciol [GO:0036378]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; response to cesium ion [GO:0010164]; response to ionizing radiation [GO:0010212]; vitamin D metabolic process [GO:0042359]; vitamin metabolic process [GO:0006766]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; vitamin D3 25-hydroxylase activity [GO:0030343]
d2ij5c__d3n9yb___1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	oxidation-reduction process [GO:0055114]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]
d2ijd21_d1qa7d___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2ijxa2_d3p83b2__1			Crenarchaeota	Euryarchaeota	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	PCNA complex [GO:0043626]		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d2ijxb2_d1unna3__1			Crenarchaeota	Proteobacteria	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	PCNA complex [GO:0043626]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d2ijxc2_d4n94a2__1			Crenarchaeota	Proteobacteria	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	PCNA complex [GO:0043626]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d2ijxd1_d3pweb2__1			Crenarchaeota	Proteobacteria	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	PCNA complex [GO:0043626]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d2ijxd2_d1vyje2__1		Metazoa	Crenarchaeota	Chordata	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	PCNA complex [GO:0043626]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d2ik2b__d4z74g1__1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d2ik6b__d1wcfa1__1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d2ik6b__d5ucqa___1	Fungi		Ascomycota	Euryarchaeota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d2ik8b1_d1agrh___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; protein folding [GO:0006457]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]; response to peptide hormone [GO:0043434]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; protein folding [GO:0006457]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]; response to peptide hormone [GO:0043434]	adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d2ikga__d2ipjb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytosol [GO:0005829]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]
d2ikua__d2psua___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]
d2ikub__d3ggvc___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2il2a__d3u7sa___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2il2b__d2f8gb___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2il3a1_d2z9sc___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]; heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]	glutathione transferase activity [GO:0004364]	heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d2il8b__d1f9sc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; chemokine activity [GO:0008009]; interleukin-8 receptor binding [GO:0005153]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; calcium-mediated signaling [GO:0019722]; cell cycle arrest [GO:0007050]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; embryonic digestive tract development [GO:0048566]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of angiogenesis [GO:0045766]; positive regulation of neutrophil chemotaxis [GO:0090023]; receptor internalization [GO:0031623]; regulation of cell adhesion [GO:0030155]; regulation of entry of bacterium into host cell [GO:2000535]; regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045091]; response to endoplasmic reticulum stress [GO:0034976]; response to molecule of bacterial origin [GO:0002237]; signal transduction [GO:0007165]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]; chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; calcium-mediated signaling [GO:0019722]; cell cycle arrest [GO:0007050]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; embryonic digestive tract development [GO:0048566]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of angiogenesis [GO:0045766]; positive regulation of neutrophil chemotaxis [GO:0090023]; receptor internalization [GO:0031623]; regulation of cell adhesion [GO:0030155]; regulation of entry of bacterium into host cell [GO:2000535]; regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045091]; response to endoplasmic reticulum stress [GO:0034976]; response to molecule of bacterial origin [GO:0002237]; signal transduction [GO:0007165]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to lipopolysaccharide [GO:0071222]; chemokine-mediated signaling pathway [GO:0070098]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of MHC class II biosynthetic process [GO:0045347]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell population proliferation [GO:0042127]; regulation of megakaryocyte differentiation [GO:0045652]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; host cell cytoplasm [GO:0030430]; platelet alpha granule lumen [GO:0031093]; symbiont-containing vacuole membrane [GO:0020005]	chemokine activity [GO:0008009]; interleukin-8 receptor binding [GO:0005153]	chemokine activity [GO:0008009]; CXCR3 chemokine receptor binding [GO:0048248]; heparin binding [GO:0008201]
d2ilia__d3m2za___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2ilka__d2psmb2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]; aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; interleukin-15 receptor activity [GO:0042010]; protein kinase binding [GO:0019901]; interleukin-15-mediated signaling pathway [GO:0035723]; negative regulation of neuron projection development [GO:0010977]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of phagocytosis [GO:0050766]; receptor signaling pathway via JAK-STAT [GO:0007259]	aging [GO:0007568]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; endothelial cell apoptotic process [GO:0072577]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte chemotaxis [GO:0030595]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of chronic inflammatory response to antigenic stimulus [GO:0002875]; negative regulation of cytokine activity [GO:0060302]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-alpha biosynthetic process [GO:0045355]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myeloid dendritic cell activation [GO:0030886]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of sensory perception of pain [GO:1904057]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of macrophage activation [GO:0043032]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; receptor biosynthetic process [GO:0032800]; regulation of gene expression [GO:0010468]; regulation of isotype switching [GO:0045191]; regulation of response to wounding [GO:1903034]; regulation of synapse organization [GO:0050807]; response to activity [GO:0014823]; response to carbon monoxide [GO:0034465]; response to glucocorticoid [GO:0051384]; response to inactivity [GO:0014854]; response to insulin [GO:0032868]; response to molecule of bacterial origin [GO:0002237]; type 2 immune response [GO:0042092]	interleukin-15-mediated signaling pathway [GO:0035723]; negative regulation of neuron projection development [GO:0010977]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of phagocytosis [GO:0050766]; receptor signaling pathway via JAK-STAT [GO:0007259]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-10 receptor binding [GO:0005141]; protein dimerization activity [GO:0046983]	interleukin-15 receptor activity [GO:0042010]; protein kinase binding [GO:0019901]
d2illa1_d2fjgl2__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]
d2ilnb__d1df9b___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	
d2ilnb__d1tawa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2ilxa2_d2i3ea1__1	Metazoa	Metazoa	Chordata	Chordata	cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; melanosome [GO:0042470]; microvillus [GO:0005902]; mitochondrial inner membrane [GO:0005743]; mitochondrial outer membrane [GO:0005741]; myelin sheath [GO:0043209]; myelin sheath abaxonal region [GO:0035748]; myelin sheath adaxonal region [GO:0035749]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; cyclic nucleotide binding [GO:0030551]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; aging [GO:0007568]; axonogenesis [GO:0007409]; cyclic nucleotide catabolic process [GO:0009214]; forebrain development [GO:0030900]; microtubule cytoskeleton organization [GO:0000226]; oligodendrocyte differentiation [GO:0048709]; regulation of mitochondrial membrane permeability [GO:0046902]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]	membrane [GO:0016020]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; cyclic nucleotide catabolic process [GO:0009214]	adult locomotory behavior [GO:0008344]; aging [GO:0007568]; axonogenesis [GO:0007409]; cyclic nucleotide catabolic process [GO:0009214]; forebrain development [GO:0030900]; microtubule cytoskeleton organization [GO:0000226]; oligodendrocyte differentiation [GO:0048709]; regulation of mitochondrial membrane permeability [GO:0046902]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]	cyclic nucleotide catabolic process [GO:0009214]	cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; melanosome [GO:0042470]; microvillus [GO:0005902]; mitochondrial inner membrane [GO:0005743]; mitochondrial outer membrane [GO:0005741]; myelin sheath [GO:0043209]; myelin sheath abaxonal region [GO:0035748]; myelin sheath adaxonal region [GO:0035749]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]	membrane [GO:0016020]	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; cyclic nucleotide binding [GO:0030551]; RNA binding [GO:0003723]	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]
d2im5a2_d3l0gc2__1			Bacteroidetes	Proteobacteria	nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]			nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2im5c2_d1qpqe1__1			Bacteroidetes	Actinobacteria	nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d2imib1_d4deje1__1	Metazoa		Arthropoda	Proteobacteria	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	transferase activity [GO:0016740]	glutathione metabolic process [GO:0006749]		cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d2imma__d1s78d1__1		Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]
d2imna__d4z78d2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2incc__d3ri7c___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]	toluene catabolic process [GO:0042203]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d2indb__d1xvcd___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular aromatic compound metabolic process [GO:0006725]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2indb__d5c6fd1__1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d2infc__d3gvva___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; uroporphyrinogen decarboxylase activity [GO:0004853]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uroporphyrinogen decarboxylase activity [GO:0004853]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	uroporphyrinogen decarboxylase activity [GO:0004853]	uroporphyrinogen decarboxylase activity [GO:0004853]
d2infd__d2q6za___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; uroporphyrinogen decarboxylase activity [GO:0004853]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uroporphyrinogen decarboxylase activity [GO:0004853]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	uroporphyrinogen decarboxylase activity [GO:0004853]	uroporphyrinogen decarboxylase activity [GO:0004853]
d2io1c__d1avpa___1	Metazoa		Chordata		cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein domain specific binding [GO:0019904]; SUMO-specific endopeptidase activity [GO:0070139]; SUMO-specific isopeptidase activity [GO:0070140]; dorsal/ventral axis specification [GO:0009950]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; labyrinthine layer development [GO:0060711]; mRNA transport [GO:0051028]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of DNA endoreduplication [GO:0032875]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of Wnt signaling pathway [GO:0030111]; spongiotrophoblast layer development [GO:0060712]; trophoblast giant cell differentiation [GO:0060707]; Wnt signaling pathway [GO:0016055]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; viral procapsid [GO:0046729]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; nuclear capsid assembly [GO:0039708]; viral release from host cell [GO:0019076]	dorsal/ventral axis specification [GO:0009950]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; labyrinthine layer development [GO:0060711]; mRNA transport [GO:0051028]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of DNA endoreduplication [GO:0032875]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of Wnt signaling pathway [GO:0030111]; spongiotrophoblast layer development [GO:0060712]; trophoblast giant cell differentiation [GO:0060707]; Wnt signaling pathway [GO:0016055]	lysis of host organelle involved in viral entry into host cell [GO:0039664]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; nuclear capsid assembly [GO:0039708]; viral release from host cell [GO:0019076]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; viral procapsid [GO:0046729]	protein domain specific binding [GO:0019904]; SUMO-specific endopeptidase activity [GO:0070139]; SUMO-specific isopeptidase activity [GO:0070140]	
d2io1f__d3kydd___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein domain specific binding [GO:0019904]; SUMO-specific endopeptidase activity [GO:0070139]; SUMO-specific isopeptidase activity [GO:0070140]; dorsal/ventral axis specification [GO:0009950]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; labyrinthine layer development [GO:0060711]; mRNA transport [GO:0051028]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of DNA endoreduplication [GO:0032875]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of Wnt signaling pathway [GO:0030111]; spongiotrophoblast layer development [GO:0060712]; trophoblast giant cell differentiation [GO:0060707]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; SUMO activating enzyme complex [GO:0031510]; ATP binding [GO:0005524]; enzyme activator activity [GO:0008047]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; small protein activating enzyme binding [GO:0044388]; SUMO activating enzyme activity [GO:0019948]; SUMO binding [GO:0032183]; transcription factor binding [GO:0008134]; transferase activity [GO:0016740]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; protein modification by small protein conjugation [GO:0032446]; protein sumoylation [GO:0016925]	dorsal/ventral axis specification [GO:0009950]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; labyrinthine layer development [GO:0060711]; mRNA transport [GO:0051028]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of DNA endoreduplication [GO:0032875]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of Wnt signaling pathway [GO:0030111]; spongiotrophoblast layer development [GO:0060712]; trophoblast giant cell differentiation [GO:0060707]; Wnt signaling pathway [GO:0016055]	protein modification by small protein conjugation [GO:0032446]; protein sumoylation [GO:0016925]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; SUMO activating enzyme complex [GO:0031510]	protein domain specific binding [GO:0019904]; SUMO-specific endopeptidase activity [GO:0070139]; SUMO-specific isopeptidase activity [GO:0070140]	ATP binding [GO:0005524]; enzyme activator activity [GO:0008047]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; small protein activating enzyme binding [GO:0044388]; SUMO activating enzyme activity [GO:0019948]; SUMO binding [GO:0032183]; transcription factor binding [GO:0008134]; transferase activity [GO:0016740]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]
d2io1f__d5m93c1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein domain specific binding [GO:0019904]; SUMO-specific endopeptidase activity [GO:0070139]; SUMO-specific isopeptidase activity [GO:0070140]; dorsal/ventral axis specification [GO:0009950]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; labyrinthine layer development [GO:0060711]; mRNA transport [GO:0051028]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of DNA endoreduplication [GO:0032875]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of Wnt signaling pathway [GO:0030111]; spongiotrophoblast layer development [GO:0060712]; trophoblast giant cell differentiation [GO:0060707]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	dorsal/ventral axis specification [GO:0009950]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; labyrinthine layer development [GO:0060711]; mRNA transport [GO:0051028]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of DNA endoreduplication [GO:0032875]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of Wnt signaling pathway [GO:0030111]; spongiotrophoblast layer development [GO:0060712]; trophoblast giant cell differentiation [GO:0060707]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	protein domain specific binding [GO:0019904]; SUMO-specific endopeptidase activity [GO:0070139]; SUMO-specific isopeptidase activity [GO:0070140]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2io2b__d5dpwg___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; nucleolus [GO:0005730]; metal ion binding [GO:0046872]; autophagy [GO:0006914]; intracellular signal transduction [GO:0035556]; lysosome localization [GO:0032418]; positive regulation of bone resorption [GO:0045780]; positive regulation of ruffle assembly [GO:1900029]; protein transport [GO:0015031]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	autophagy [GO:0006914]; intracellular signal transduction [GO:0035556]; lysosome localization [GO:0032418]; positive regulation of bone resorption [GO:0045780]; positive regulation of ruffle assembly [GO:1900029]; protein transport [GO:0015031]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; nucleolus [GO:0005730]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]	metal ion binding [GO:0046872]
d2io2c1_d1kpsd___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]; ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]
d2io3a1_d2bkra___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein domain specific binding [GO:0019904]; SUMO-specific endopeptidase activity [GO:0070139]; SUMO-specific isopeptidase activity [GO:0070140]; dorsal/ventral axis specification [GO:0009950]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; labyrinthine layer development [GO:0060711]; mRNA transport [GO:0051028]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of DNA endoreduplication [GO:0032875]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of Wnt signaling pathway [GO:0030111]; spongiotrophoblast layer development [GO:0060712]; trophoblast giant cell differentiation [GO:0060707]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	dorsal/ventral axis specification [GO:0009950]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; labyrinthine layer development [GO:0060711]; mRNA transport [GO:0051028]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of DNA endoreduplication [GO:0032875]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of Wnt signaling pathway [GO:0030111]; spongiotrophoblast layer development [GO:0060712]; trophoblast giant cell differentiation [GO:0060707]; Wnt signaling pathway [GO:0016055]	anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protein domain specific binding [GO:0019904]; SUMO-specific endopeptidase activity [GO:0070139]; SUMO-specific isopeptidase activity [GO:0070140]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2io4b1_d1dmlc1__1			Crenarchaeota		PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	host cell nucleus [GO:0042025]; DNA binding [GO:0003677]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]	PCNA complex [GO:0043626]	host cell nucleus [GO:0042025]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	DNA binding [GO:0003677]
d2io4b2_d5a6db1__1			Crenarchaeota	Euryarchaeota	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	PCNA complex [GO:0043626]		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d2io5c__d2pyoh___1	Metazoa	Metazoa	Chordata	Arthropoda	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]		chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2ioba1_d3etja2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutathionylspermidine amidase activity [GO:0008884]; glutathionylspermidine synthase activity [GO:0008885]; metal ion binding [GO:0046872]; glutathione metabolic process [GO:0006749]; spermidine metabolic process [GO:0008216]	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	glutathione metabolic process [GO:0006749]; spermidine metabolic process [GO:0008216]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; glutathionylspermidine amidase activity [GO:0008884]; glutathionylspermidine synthase activity [GO:0008885]; metal ion binding [GO:0046872]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]
d2ioba2_d1zcma1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutathionylspermidine amidase activity [GO:0008884]; glutathionylspermidine synthase activity [GO:0008885]; metal ion binding [GO:0046872]; glutathione metabolic process [GO:0006749]; spermidine metabolic process [GO:0008216]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; mammary gland involution [GO:0060056]; neutrophil degranulation [GO:0043312]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; receptor catabolic process [GO:0032801]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of NMDA receptor activity [GO:2000310]; self proteolysis [GO:0097264]	glutathione metabolic process [GO:0006749]; spermidine metabolic process [GO:0008216]	cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; mammary gland involution [GO:0060056]; neutrophil degranulation [GO:0043312]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; receptor catabolic process [GO:0032801]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of NMDA receptor activity [GO:2000310]; self proteolysis [GO:0097264]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glutathionylspermidine amidase activity [GO:0008884]; glutathionylspermidine synthase activity [GO:0008885]; metal ion binding [GO:0046872]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d2iobb1_d2w6qa1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutathionylspermidine amidase activity [GO:0008884]; glutathionylspermidine synthase activity [GO:0008885]; metal ion binding [GO:0046872]; glutathione metabolic process [GO:0006749]; spermidine metabolic process [GO:0008216]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	glutathione metabolic process [GO:0006749]; spermidine metabolic process [GO:0008216]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; glutathionylspermidine amidase activity [GO:0008884]; glutathionylspermidine synthase activity [GO:0008885]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2iofa__d1z5gc___1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	organic phosphonate catabolic process [GO:0019700]			outer membrane-bounded periplasmic space [GO:0030288]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]
d2ioga__d1a28b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transcriptional preinitiation complex [GO:0097550]; transcriptionally active chromatin [GO:0035327]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor activity [GO:0030284]; estrogen receptor binding [GO:0030331]; estrogen response element binding [GO:0034056]; identical protein binding [GO:0042802]; nitric-oxide synthase regulator activity [GO:0030235]; nuclear receptor activity [GO:0004879]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; steroid binding [GO:0005496]; TBP-class protein binding [GO:0017025]; TFIIB-class transcription factor binding [GO:0001093]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; androgen metabolic process [GO:0008209]; antral ovarian follicle growth [GO:0001547]; cellular response to estradiol stimulus [GO:0071392]; cellular response to estrogen stimulus [GO:0071391]; chromatin remodeling [GO:0006338]; epithelial cell development [GO:0002064]; epithelial cell proliferation involved in mammary gland duct elongation [GO:0060750]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; male gonad development [GO:0008584]; mammary gland alveolus development [GO:0060749]; mammary gland branching involved in pregnancy [GO:0060745]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; protein deubiquitination [GO:0016579]; protein localization to chromatin [GO:0071168]; regulation of apoptotic process [GO:0042981]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of inflammatory response [GO:0050727]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; signal transduction [GO:0007165]; stem cell differentiation [GO:0048863]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]; uterus development [GO:0060065]; vagina development [GO:0060068]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; ATPase binding [GO:0051117]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclear receptor activity [GO:0004879]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]; cell-cell signaling [GO:0007267]; epithelial cell maturation [GO:0002070]; lung alveolus development [GO:0048286]; negative regulation of gene expression [GO:0010629]; ovulation from ovarian follicle [GO:0001542]; paracrine signaling [GO:0038001]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; regulation of epithelial cell proliferation [GO:0050678]; signal transduction [GO:0007165]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription initiation from RNA polymerase II promoter [GO:0006367]	androgen metabolic process [GO:0008209]; antral ovarian follicle growth [GO:0001547]; cellular response to estradiol stimulus [GO:0071392]; cellular response to estrogen stimulus [GO:0071391]; chromatin remodeling [GO:0006338]; epithelial cell development [GO:0002064]; epithelial cell proliferation involved in mammary gland duct elongation [GO:0060750]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; male gonad development [GO:0008584]; mammary gland alveolus development [GO:0060749]; mammary gland branching involved in pregnancy [GO:0060745]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; protein deubiquitination [GO:0016579]; protein localization to chromatin [GO:0071168]; regulation of apoptotic process [GO:0042981]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of inflammatory response [GO:0050727]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; signal transduction [GO:0007165]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; uterus development [GO:0060065]; vagina development [GO:0060068]	cell-cell signaling [GO:0007267]; epithelial cell maturation [GO:0002070]; lung alveolus development [GO:0048286]; negative regulation of gene expression [GO:0010629]; ovulation from ovarian follicle [GO:0001542]; paracrine signaling [GO:0038001]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; regulation of epithelial cell proliferation [GO:0050678]; signal transduction [GO:0007165]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transcriptionally active chromatin [GO:0035327]; transcriptional preinitiation complex [GO:0097550]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]	ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor activity [GO:0030284]; estrogen receptor binding [GO:0030331]; estrogen response element binding [GO:0034056]; identical protein binding [GO:0042802]; nitric-oxide synthase regulator activity [GO:0030235]; nuclear receptor activity [GO:0004879]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; steroid binding [GO:0005496]; TBP-class protein binding [GO:0017025]; TFIIB-class transcription factor binding [GO:0001093]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	ATPase binding [GO:0051117]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclear receptor activity [GO:0004879]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]
d2iohb__d3e8ma___1			Firmicutes	Bacteroidetes	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	organic phosphonate catabolic process [GO:0019700]	lipopolysaccharide biosynthetic process [GO:0009103]			magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d2iohd__d1rqlb___1			Firmicutes	Firmicutes	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	organic phosphonate catabolic process [GO:0019700]	organic phosphonate catabolic process [GO:0019700]			magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]
d2iooa__d1imhd2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; central nervous system development [GO:0007417]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; chromosome organization [GO:0051276]; circadian behavior [GO:0048512]; circadian rhythm [GO:0007623]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; heart development [GO:0007507]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of mitophagy [GO:1901525]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron apoptotic process [GO:0043523]; regulation of thymocyte apoptotic process [GO:0070243]; regulation of tissue remodeling [GO:0034103]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to caffeine [GO:0031000]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to oxidative stress [GO:0006979]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cytokine production [GO:0001816]; excretion [GO:0007588]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; response to osmotic stress [GO:0006970]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]	apoptotic process [GO:0006915]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; central nervous system development [GO:0007417]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; chromosome organization [GO:0051276]; circadian behavior [GO:0048512]; circadian rhythm [GO:0007623]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; heart development [GO:0007507]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of mitophagy [GO:1901525]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron apoptotic process [GO:0043523]; regulation of thymocyte apoptotic process [GO:0070243]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to caffeine [GO:0031000]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to oxidative stress [GO:0006979]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cytokine production [GO:0001816]; excretion [GO:0007588]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; response to osmotic stress [GO:0006970]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]	cell [GO:0005623]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d2ioua2_d4mrfa1__1		Metazoa		Chordata	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	virus tail, fiber [GO:0098024]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d2ioue2_d1bcj11__1		Metazoa		Chordata	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	virus tail, fiber [GO:0098024]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]		calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d2ip4b3_d5veva3__1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d2ipaa__d1fova___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; deoxyribonucleotide biosynthetic process [GO:0009263]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; deoxyribonucleotide biosynthetic process [GO:0009263]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]
d2ipab__d1d1qb___1		Fungi	Firmicutes	Ascomycota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; acid phosphatase activity [GO:0003993]; protein tyrosine phosphatase activity [GO:0004725]; protein dephosphorylation [GO:0006470]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	protein dephosphorylation [GO:0006470]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	acid phosphatase activity [GO:0003993]; protein tyrosine phosphatase activity [GO:0004725]
d2ipgb__d4ijca___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; D-arabinose 1-dehydrogenase [NAD(P)+] activity [GO:0045290]; oxidoreductase activity [GO:0016491]; cellular carbohydrate metabolic process [GO:0044262]	oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	cellular carbohydrate metabolic process [GO:0044262]	cytosol [GO:0005829]	cytosol [GO:0005829]	17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; D-arabinose 1-dehydrogenase [NAD(P)+] activity [GO:0045290]; oxidoreductase activity [GO:0016491]
d2ipjb__d3wbxb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]		cytosol [GO:0005829]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2ipna__d4rk0a___1			Proteobacteria	Firmicutes	outer membrane-bounded periplasmic space [GO:0030288]; metal ion binding [GO:0046872]; chemotaxis [GO:0006935]; galactose transmembrane transport [GO:0015757]; methylgalactoside transport [GO:0015765]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	chemotaxis [GO:0006935]; galactose transmembrane transport [GO:0015757]; methylgalactoside transport [GO:0015765]	regulation of transcription, DNA-templated [GO:0006355]	outer membrane-bounded periplasmic space [GO:0030288]		metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d2ipoa2_d6at1c2__1			Proteobacteria	Proteobacteria	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]; zinc ion binding [GO:0008270]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2ipoc2_d4oh7a1__1			Proteobacteria	Proteobacteria	aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]; zinc ion binding [GO:0008270]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]		aspartate carbamoyltransferase complex [GO:0009347]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d2ipra__d1ksxj___1					host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA replication [GO:0006260]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]	host cell nucleus [GO:0042025]	host cell nucleus [GO:0042025]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]
d2iptl2_d2jixd2__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d2iptl2_d5vkhb1__1	Metazoa		Chordata	Actinobacteria	metal ion binding [GO:0046872]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d2ipya2_d1nisa1__1		Metazoa		Chordata		cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]		citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; mitochondrion [GO:0005739]		3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]
d2ipyb2_d1b0ka1__1		Metazoa		Chordata		cytosol [GO:0005829]; mitochondrion [GO:0005739]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; metal ion binding [GO:0046872]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; mitochondrion [GO:0005739]		4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; metal ion binding [GO:0046872]
d2iq7c__d1o88a___1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]
d2iq7f__d1nhcc___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	polygalacturonase activity [GO:0004650]
d2iq7f__d1qjva___1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	polygalacturonase activity [GO:0004650]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]
d2iq9l2_d1igch2__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	metal ion binding [GO:0046872]	
d2iqaa1_d5cbed___1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	antigen binding [GO:0003823]
d2iqal2_d3l5xl2__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]	cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]
d2irfg__d3qu3b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cell population proliferation [GO:0008283]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer sequence-specific DNA binding [GO:0001158]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; immunoglobulin mediated immune response [GO:0016064]; interferon-alpha production [GO:0032607]; interferon-beta production [GO:0032608]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of adaptive immune response [GO:0002819]; regulation of gene expression [GO:0010468]; regulation of innate immune response [GO:0045088]; regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034124]; regulation of MyD88-independent toll-like receptor signaling pathway [GO:0034127]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]	cell population proliferation [GO:0008283]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]	defense response to virus [GO:0051607]; immune system process [GO:0002376]; immunoglobulin mediated immune response [GO:0016064]; interferon-alpha production [GO:0032607]; interferon-beta production [GO:0032608]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; regulation of adaptive immune response [GO:0002819]; regulation of gene expression [GO:0010468]; regulation of innate immune response [GO:0045088]; regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034124]; regulation of MyD88-independent toll-like receptor signaling pathway [GO:0034127]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]	cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer sequence-specific DNA binding [GO:0001158]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d2irwe__d4ajoc1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	cytoplasm [GO:0005737]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2is8b__d1o8oc___1		Viridiplantae	Deinococcus-Thermus	Streptophyta	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; auxin-activated signaling pathway [GO:0009734]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; response to metal ion [GO:0010038]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	auxin-activated signaling pathway [GO:0009734]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; response to metal ion [GO:0010038]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]
d2iscb1_d5c80a___1				Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]		cytoplasm [GO:0005737]	purine-nucleoside phosphorylase activity [GO:0004731]	metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]
d2isea1_d5taia___1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	negative regulation of neurotransmitter secretion [GO:0046929]		cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d2iszb2_d1bi2a2__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein dimerization activity [GO:0046983]; SH3 domain binding [GO:0017124]; transition metal ion binding [GO:0046914]; protein homooligomerization [GO:0051260]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]	protein homooligomerization [GO:0051260]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein dimerization activity [GO:0046983]; SH3 domain binding [GO:0017124]; transition metal ion binding [GO:0046914]
d2it0a1_d1f5td1__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein dimerization activity [GO:0046983]; SH3 domain binding [GO:0017124]; transition metal ion binding [GO:0046914]; protein homooligomerization [GO:0051260]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; siderophore biosynthetic process from catechol [GO:0019540]	protein homooligomerization [GO:0051260]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	cadmium ion binding [GO:0046870]; cobalt ion binding [GO:0050897]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nickel cation binding [GO:0016151]; protein dimerization activity [GO:0046983]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; protein dimerization activity [GO:0046983]; SH3 domain binding [GO:0017124]; transition metal ion binding [GO:0046914]
d2it4b__d4uovf___1	Metazoa		Chordata	Aquificae	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2it6a__d2yhfd___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]; cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]	carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]
d2itda2_d3q3gj2__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	voltage-gated potassium channel complex [GO:0008076]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]
d2itha__d1pd8a___1		Metazoa	Euryarchaeota	Chordata	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d2iu2a__d2rdbb___1	Metazoa		Chordata	Proteobacteria	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular aromatic compound metabolic process [GO:0006725]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d2iu7a2_d2ivgd2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2iu7b1_d3f51b1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; positive regulation of transcription, DNA-templated [GO:0045893]	cyanate catabolic process [GO:0009440]	positive regulation of transcription, DNA-templated [GO:0045893]	cytoplasm [GO:0005737]	protein-DNA complex [GO:0032993]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	DNA-binding transcription activator activity [GO:0001216]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2iu7j1_d1zz9c1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	cyanate catabolic process [GO:0009440]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d2iuha1_d2dx0a___1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; cell-cell junction [GO:0005911]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; mast cell granule [GO:0042629]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; cytokine binding [GO:0019955]; metal ion binding [GO:0046872]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; stem cell factor receptor activity [GO:0005020]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; actin cytoskeleton reorganization [GO:0031532]; activation of MAPK activity [GO:0000187]; B cell differentiation [GO:0030183]; cell chemotaxis [GO:0060326]; cellular response to thyroid hormone stimulus [GO:0097067]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell cytokine production [GO:0002371]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; digestive tract development [GO:0048565]; ectopic germ cell programmed cell death [GO:0035234]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation [GO:0050673]; erythrocyte differentiation [GO:0030218]; erythropoietin-mediated signaling pathway [GO:0038162]; Fc receptor signaling pathway [GO:0038093]; germ cell migration [GO:0008354]; glycosphingolipid metabolic process [GO:0006687]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell migration [GO:0035701]; hemopoiesis [GO:0030097]; immature B cell differentiation [GO:0002327]; inflammatory response [GO:0006954]; Kit signaling pathway [GO:0038109]; lamellipodium assembly [GO:0030032]; lymphoid progenitor cell differentiation [GO:0002320]; male gonad development [GO:0008584]; MAPK cascade [GO:0000165]; mast cell chemotaxis [GO:0002551]; mast cell cytokine production [GO:0032762]; mast cell degranulation [GO:0043303]; mast cell differentiation [GO:0060374]; mast cell proliferation [GO:0070662]; megakaryocyte development [GO:0035855]; melanocyte adhesion [GO:0097326]; melanocyte differentiation [GO:0030318]; melanocyte migration [GO:0097324]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of programmed cell death [GO:0043069]; ovarian follicle development [GO:0001541]; peptidyl-tyrosine phosphorylation [GO:0018108]; pigmentation [GO:0043473]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of colon smooth muscle contraction [GO:1904343]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of pyloric antrum smooth muscle contraction [GO:0120072]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of small intestine smooth muscle contraction [GO:1904349]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell differentiation [GO:1905065]; protein autophosphorylation [GO:0046777]; regulation of bile acid metabolic process [GO:1904251]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of transcription by RNA polymerase II [GO:0006357]; response to cadmium ion [GO:0046686]; signal transduction [GO:0007165]; somatic stem cell division [GO:0048103]; somatic stem cell population maintenance [GO:0035019]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]; T cell differentiation [GO:0030217]; tongue development [GO:0043586]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; visual learning [GO:0008542]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase C activity [GO:0004629]; phosphotyrosine residue binding [GO:0001784]; activation of store-operated calcium channel activity [GO:0032237]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; follicular B cell differentiation [GO:0002316]; inositol trisphosphate biosynthetic process [GO:0032959]; negative regulation of programmed cell death [GO:0043069]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipid catabolic process [GO:0009395]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of receptor internalization [GO:0002092]; positive regulation of type I interferon production [GO:0032481]; regulation of gene expression [GO:0010468]; release of sequestered calcium ion into cytosol [GO:0051209]; response to ATP [GO:0033198]; response to lipopolysaccharide [GO:0032496]; response to magnesium ion [GO:0032026]; T cell receptor signaling pathway [GO:0050852]	actin cytoskeleton reorganization [GO:0031532]; activation of MAPK activity [GO:0000187]; B cell differentiation [GO:0030183]; cell chemotaxis [GO:0060326]; cellular response to thyroid hormone stimulus [GO:0097067]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell cytokine production [GO:0002371]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; digestive tract development [GO:0048565]; ectopic germ cell programmed cell death [GO:0035234]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation [GO:0050673]; erythrocyte differentiation [GO:0030218]; erythropoietin-mediated signaling pathway [GO:0038162]; Fc receptor signaling pathway [GO:0038093]; germ cell migration [GO:0008354]; glycosphingolipid metabolic process [GO:0006687]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell migration [GO:0035701]; hemopoiesis [GO:0030097]; immature B cell differentiation [GO:0002327]; inflammatory response [GO:0006954]; Kit signaling pathway [GO:0038109]; lamellipodium assembly [GO:0030032]; lymphoid progenitor cell differentiation [GO:0002320]; male gonad development [GO:0008584]; MAPK cascade [GO:0000165]; mast cell chemotaxis [GO:0002551]; mast cell cytokine production [GO:0032762]; mast cell degranulation [GO:0043303]; mast cell differentiation [GO:0060374]; mast cell proliferation [GO:0070662]; megakaryocyte development [GO:0035855]; melanocyte adhesion [GO:0097326]; melanocyte differentiation [GO:0030318]; melanocyte migration [GO:0097324]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of programmed cell death [GO:0043069]; ovarian follicle development [GO:0001541]; peptidyl-tyrosine phosphorylation [GO:0018108]; pigmentation [GO:0043473]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of colon smooth muscle contraction [GO:1904343]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of pyloric antrum smooth muscle contraction [GO:0120072]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of small intestine smooth muscle contraction [GO:1904349]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell differentiation [GO:1905065]; protein autophosphorylation [GO:0046777]; regulation of bile acid metabolic process [GO:1904251]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of transcription by RNA polymerase II [GO:0006357]; response to cadmium ion [GO:0046686]; signal transduction [GO:0007165]; somatic stem cell division [GO:0048103]; somatic stem cell population maintenance [GO:0035019]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]; T cell differentiation [GO:0030217]; tongue development [GO:0043586]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; visual learning [GO:0008542]	activation of store-operated calcium channel activity [GO:0032237]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; follicular B cell differentiation [GO:0002316]; inositol trisphosphate biosynthetic process [GO:0032959]; negative regulation of programmed cell death [GO:0043069]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipid catabolic process [GO:0009395]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of receptor internalization [GO:0002092]; positive regulation of type I interferon production [GO:0032481]; regulation of gene expression [GO:0010468]; release of sequestered calcium ion into cytosol [GO:0051209]; response to ATP [GO:0033198]; response to lipopolysaccharide [GO:0032496]; response to magnesium ion [GO:0032026]; T cell receptor signaling pathway [GO:0050852]	acrosomal vesicle [GO:0001669]; cell-cell junction [GO:0005911]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; mast cell granule [GO:0042629]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; cytokine binding [GO:0019955]; metal ion binding [GO:0046872]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; stem cell factor receptor activity [GO:0005020]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase C activity [GO:0004629]; phosphotyrosine residue binding [GO:0001784]
d2iuia1_d4je4a1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]; 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; insulin binding [GO:0043559]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; insulin-like growth factor receptor binding [GO:0005159]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; axon guidance [GO:0007411]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]; abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	axon guidance [GO:0007411]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; platelet activation [GO:0030168]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; insulin binding [GO:0043559]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]	cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]
d2iuib1_d5tnwb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]; 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; insulin binding [GO:0043559]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; insulin-like growth factor receptor binding [GO:0005159]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; axon guidance [GO:0007411]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cell [GO:0005623]; COP9 signalosome [GO:0008180]; lamellipodium [GO:0030027]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; phosphatidylinositol phospholipase C activity [GO:0004435]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; in utero embryonic development [GO:0001701]; inositol trisphosphate biosynthetic process [GO:0032959]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipid catabolic process [GO:0009395]; positive regulation of epithelial cell migration [GO:0010634]; release of sequestered calcium ion into cytosol [GO:0051209]	axon guidance [GO:0007411]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; platelet activation [GO:0030168]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; inositol trisphosphate biosynthetic process [GO:0032959]; in utero embryonic development [GO:0001701]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipid catabolic process [GO:0009395]; positive regulation of epithelial cell migration [GO:0010634]; release of sequestered calcium ion into cytosol [GO:0051209]	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; plasma membrane [GO:0005886]	cell [GO:0005623]; COP9 signalosome [GO:0008180]; lamellipodium [GO:0030027]; ruffle [GO:0001726]	1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; insulin binding [GO:0043559]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]	calcium ion binding [GO:0005509]; phosphatidylinositol phospholipase C activity [GO:0004435]
d2iuja2_d1rrha1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; oxylipin biosynthetic process [GO:0031408]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; oxylipin biosynthetic process [GO:0031408]	oxylipin biosynthetic process [GO:0031408]	oxylipin biosynthetic process [GO:0031408]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]	metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d2iukb2_d2p0mb1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; oxylipin biosynthetic process [GO:0031408]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]; arachidonate 12-lipoxygenase activity [GO:0004052]; arachidonate 15-lipoxygenase activity [GO:0050473]; iron ion binding [GO:0005506]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; apoptotic cell clearance [GO:0043277]; arachidonic acid metabolic process [GO:0019369]; bone mineralization [GO:0030282]; cellular response to calcium ion [GO:0071277]; cellular response to interleukin-13 [GO:0035963]; hepoxilin biosynthetic process [GO:0051122]; linoleic acid metabolic process [GO:0043651]; lipoxin A4 biosynthetic process [GO:2001303]; lipoxygenase pathway [GO:0019372]; negative regulation of adaptive immune response [GO:0002820]; ossification [GO:0001503]; phosphatidylethanolamine biosynthetic process [GO:0006646]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of engulfment of apoptotic cell [GO:1901074]; regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035358]; response to endoplasmic reticulum stress [GO:0034976]; wound healing [GO:0042060]	oxylipin biosynthetic process [GO:0031408]	apoptotic cell clearance [GO:0043277]; arachidonic acid metabolic process [GO:0019369]; bone mineralization [GO:0030282]; cellular response to calcium ion [GO:0071277]; cellular response to interleukin-13 [GO:0035963]; hepoxilin biosynthetic process [GO:0051122]; linoleic acid metabolic process [GO:0043651]; lipoxin A4 biosynthetic process [GO:2001303]; lipoxygenase pathway [GO:0019372]; negative regulation of adaptive immune response [GO:0002820]; ossification [GO:0001503]; phosphatidylethanolamine biosynthetic process [GO:0006646]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of engulfment of apoptotic cell [GO:1901074]; regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035358]; response to endoplasmic reticulum stress [GO:0034976]; wound healing [GO:0042060]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]	arachidonate 12-lipoxygenase activity [GO:0004052]; arachidonate 15-lipoxygenase activity [GO:0050473]; iron ion binding [GO:0005506]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]
d2iuob1_d5woqc___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	DNA binding [GO:0003677]	cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2iuog1_d1neqa___1			Proteobacteria		cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	host cell cytoplasm [GO:0030430]; transcriptional repressor complex [GO:0017053]; DNA binding [GO:0003677]	cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]	host cell cytoplasm [GO:0030430]; transcriptional repressor complex [GO:0017053]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2iuog2_d2ivga2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2iuog2_d4y42j2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate metabolic process [GO:0009439]	cyanate catabolic process [GO:0009440]	cyanate metabolic process [GO:0009439]	cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2iuoh2_d4y42c2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate metabolic process [GO:0009439]	cyanate catabolic process [GO:0009440]	cyanate metabolic process [GO:0009439]	cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2iuoj1_d4i6ud___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	DNA binding [GO:0003677]	cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2iuoj2_d2iu7g2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2iv1a1_d3g5gd___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	DNA binding [GO:0003677]	cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2iv1c2_d4y42h2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate metabolic process [GO:0009439]	cyanate catabolic process [GO:0009440]	cyanate metabolic process [GO:0009439]	cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2iv1h1_d1nera___1			Proteobacteria		cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	host cell cytoplasm [GO:0030430]; transcriptional repressor complex [GO:0017053]; DNA binding [GO:0003677]	cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]	host cell cytoplasm [GO:0030430]; transcriptional repressor complex [GO:0017053]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2iv1i1_d4i6uf___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	DNA binding [GO:0003677]	cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2iv9b1_d1iu1a___1	Metazoa	Metazoa	Chordata	Chordata	AP-2 adaptor complex [GO:0030122]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]; clathrin binding [GO:0030276]; protein-containing complex binding [GO:0044877]; signal sequence binding [GO:0005048]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; coronary vasculature development [GO:0060976]; ephrin receptor signaling pathway [GO:0048013]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; membrane organization [GO:0061024]; negative regulation of neuron death [GO:1901215]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein localization to membrane [GO:1905477]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; regulation of defense response to virus by virus [GO:0050690]; synaptic vesicle endocytosis [GO:0048488]; ventricular septum development [GO:0003281]; vesicle-mediated transport [GO:0016192]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; recycling endosome [GO:0055037]; trans-Golgi network membrane [GO:0032588]; GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; Rab GTPase binding [GO:0017137]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; regulation of defense response to virus by virus [GO:0050690]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; coronary vasculature development [GO:0060976]; ephrin receptor signaling pathway [GO:0048013]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; membrane organization [GO:0061024]; negative regulation of neuron death [GO:1901215]; positive regulation of endocytosis [GO:0045807]; positive regulation of protein localization to membrane [GO:1905477]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; regulation of defense response to virus by virus [GO:0050690]; synaptic vesicle endocytosis [GO:0048488]; ventricular septum development [GO:0003281]; vesicle-mediated transport [GO:0016192]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; regulation of defense response to virus by virus [GO:0050690]	AP-2 adaptor complex [GO:0030122]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endolysosome membrane [GO:0036020]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; presynapse [GO:0098793]	AP-1 adaptor complex [GO:0030121]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; recycling endosome [GO:0055037]; trans-Golgi network membrane [GO:0032588]	clathrin binding [GO:0030276]; protein-containing complex binding [GO:0044877]; signal sequence binding [GO:0005048]	GTP-dependent protein binding [GO:0030742]; kinesin binding [GO:0019894]; Rab GTPase binding [GO:0017137]
d2ivba2_d6b6ma2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate metabolic process [GO:0009439]	cyanate catabolic process [GO:0009440]	cyanate metabolic process [GO:0009439]	cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2ivbf1_d2grla1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	transcriptional repressor complex [GO:0017053]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]	cyanate catabolic process [GO:0009440]	negative regulation of transcription, DNA-templated [GO:0045892]	cytoplasm [GO:0005737]	transcriptional repressor complex [GO:0017053]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2ivbh1_d2bnmb1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	cyanate catabolic process [GO:0009440]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d2ivbh2_d2iv1d2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2ivdb2_d2xfpa2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; oxygen-dependent protoporphyrinogen oxidase activity [GO:0004729]; protoporphyrinogen IX biosynthetic process [GO:0006782]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	protoporphyrinogen IX biosynthetic process [GO:0006782]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; membrane [GO:0016020]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	oxygen-dependent protoporphyrinogen oxidase activity [GO:0004729]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d2ivdb2_d3b6da2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; oxygen-dependent protoporphyrinogen oxidase activity [GO:0004729]; protoporphyrinogen IX biosynthetic process [GO:0006782]	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	protoporphyrinogen IX biosynthetic process [GO:0006782]	cholesterol metabolic process [GO:0008203]	cytoplasm [GO:0005737]; membrane [GO:0016020]	extracellular region [GO:0005576]	oxygen-dependent protoporphyrinogen oxidase activity [GO:0004729]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]
d2ivea2_d1f8sb2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; oxygen-dependent protoporphyrinogen oxidase activity [GO:0004729]; protoporphyrinogen IX biosynthetic process [GO:0006782]	extracellular region [GO:0005576]; L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	protoporphyrinogen IX biosynthetic process [GO:0006782]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytoplasm [GO:0005737]; membrane [GO:0016020]	extracellular region [GO:0005576]	oxygen-dependent protoporphyrinogen oxidase activity [GO:0004729]	L-amino-acid oxidase activity [GO:0001716]; toxin activity [GO:0090729]
d2iveb2_d1ijha2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; membrane [GO:0016020]; oxygen-dependent protoporphyrinogen oxidase activity [GO:0004729]; protoporphyrinogen IX biosynthetic process [GO:0006782]	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	protoporphyrinogen IX biosynthetic process [GO:0006782]	cholesterol metabolic process [GO:0008203]	cytoplasm [GO:0005737]; membrane [GO:0016020]	extracellular region [GO:0005576]	oxygen-dependent protoporphyrinogen oxidase activity [GO:0004729]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]
d2iveb2_d2uxxa3__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; oxygen-dependent protoporphyrinogen oxidase activity [GO:0004729]; protoporphyrinogen IX biosynthetic process [GO:0006782]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	protoporphyrinogen IX biosynthetic process [GO:0006782]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cytoplasm [GO:0005737]; membrane [GO:0016020]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	oxygen-dependent protoporphyrinogen oxidase activity [GO:0004729]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2ivga2_d4y42a2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate metabolic process [GO:0009439]	cyanate catabolic process [GO:0009440]	cyanate metabolic process [GO:0009439]	cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2ivgb2_d2ivqc2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2ivgd1_d4fbib___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	DNA binding [GO:0003677]	cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2ivgd2_d4y42b2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate metabolic process [GO:0009439]	cyanate catabolic process [GO:0009440]	cyanate metabolic process [GO:0009439]	cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2ivgg2_d2iu7c2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2ivgi1_d1adra___1			Proteobacteria		cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	DNA binding [GO:0003677]	cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2ivgi2_d4y42e2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate metabolic process [GO:0009439]	cyanate catabolic process [GO:0009440]	cyanate metabolic process [GO:0009439]	cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2ivgj2_d2iv1e2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cyanate catabolic process [GO:0009440]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2ivka__d2vnda___1			Proteobacteria	Proteobacteria	endonuclease activity [GO:0004519]	extracellular region [GO:0005576]; deoxyribonuclease activity [GO:0004536]; endonuclease activity [GO:0004519]; DNA catabolic process [GO:0006308]		DNA catabolic process [GO:0006308]		extracellular region [GO:0005576]	endonuclease activity [GO:0004519]	deoxyribonuclease activity [GO:0004536]; endonuclease activity [GO:0004519]
d2ivkc__d2g7ea___1			Proteobacteria	Proteobacteria	endonuclease activity [GO:0004519]	endonuclease activity [GO:0004519]					endonuclease activity [GO:0004519]	endonuclease activity [GO:0004519]
d2ivqb1_d3clcc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	DNA binding [GO:0003677]	cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2ivqg2_d4y42f2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate metabolic process [GO:0009439]	cyanate catabolic process [GO:0009440]	cyanate metabolic process [GO:0009439]	cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d2ivqj1_d4i6ta___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]	DNA binding [GO:0003677]	cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]		cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2ivxa1_d1ogud1__1	Metazoa	Metazoa	Chordata	Chordata	cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; 7SK snRNA binding [GO:0097322]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]; RNA polymerase binding [GO:0070063]; transcription coactivator binding [GO:0001223]; cell cycle [GO:0007049]; cell division [GO:0051301]; early viral transcription [GO:0019085]; late viral transcription [GO:0019086]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of muscle cell differentiation [GO:0051147]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle tissue development [GO:0007519]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell cycle [GO:0007049]; cell division [GO:0051301]; early viral transcription [GO:0019085]; late viral transcription [GO:0019086]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of muscle cell differentiation [GO:0051147]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle tissue development [GO:0007519]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	7SK snRNA binding [GO:0097322]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]; RNA polymerase binding [GO:0070063]; transcription coactivator binding [GO:0001223]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2ivxa2_d2iw8d1__1	Metazoa	Metazoa	Chordata	Chordata	cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; 7SK snRNA binding [GO:0097322]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]; RNA polymerase binding [GO:0070063]; transcription coactivator binding [GO:0001223]; cell cycle [GO:0007049]; cell division [GO:0051301]; early viral transcription [GO:0019085]; late viral transcription [GO:0019086]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of muscle cell differentiation [GO:0051147]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle tissue development [GO:0007519]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell cycle [GO:0007049]; cell division [GO:0051301]; early viral transcription [GO:0019085]; late viral transcription [GO:0019086]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of muscle cell differentiation [GO:0051147]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle tissue development [GO:0007519]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	7SK snRNA binding [GO:0097322]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901]; RNA polymerase binding [GO:0070063]; transcription coactivator binding [GO:0001223]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2iw5a3_d3bhkb2__1	Metazoa		Chordata	Firmicutes	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	tetrahydrofolate metabolic process [GO:0046653]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	sarcosine oxidase activity [GO:0008115]
d2iw6d1_d3bhtd1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2iw8b2_d4un0a2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cyclin K-CDK12 complex [GO:0002944]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin K-CDK12 complex [GO:0002944]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]
d2iwfa2_d2fjsa1__1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	membrane [GO:0016020]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2iwfb2_d4enza2__1		Metazoa	Proteobacteria	Chordata	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	denitrification pathway [GO:0019333]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	membrane [GO:0016020]; periplasmic space [GO:0042597]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d2iwfb2_d4jknb___1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]	oxidation-reduction process [GO:0055114]	membrane [GO:0016020]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2iwga2_d1mi5d1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2iwgd1_d1c12b1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2iwgd1_d3o6fa2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2iwgd2_d4rqqa2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2iwkb2_d2j5wa1__1		Metazoa	Proteobacteria	Chordata	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	denitrification pathway [GO:0019333]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	membrane [GO:0016020]; periplasmic space [GO:0042597]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d2iwma__d3pvab___1			Firmicutes	Firmicutes	penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]	penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]			penicillin amidase activity [GO:0008953]	penicillin amidase activity [GO:0008953]
d2iwpb1_d1k32f1__1	Metazoa		Chordata	Euryarchaeota	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; protein C-terminus binding [GO:0008022]; cell adhesion [GO:0007155]; viral process [GO:0016032]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	cell adhesion [GO:0007155]; viral process [GO:0016032]	proteolysis [GO:0006508]	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	cytoplasm [GO:0005737]	protein C-terminus binding [GO:0008022]	serine-type peptidase activity [GO:0008236]
d2iwtb__d5fnwa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	endopeptidase inhibitor activity [GO:0004866]; peptidase activity [GO:0008233]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]		protein disulfide oxidoreductase activity [GO:0015035]	endopeptidase inhibitor activity [GO:0004866]; peptidase activity [GO:0008233]
d2iwxa__d1byqa___1	Fungi	Metazoa	Ascomycota	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d2iwya1_d1ulqc1__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]		cytosol [GO:0005829]; mitochondrion [GO:0005739]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2iwyb1_d2hdbb2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	isoprenoid biosynthetic process [GO:0008299]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d2iwyb2_d2vb8a1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2iwzb1_d1dlvb1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2ix0a3_d1qvcc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3'-5' exonuclease activity [GO:0008408]; exoribonuclease II activity [GO:0008859]; RNA binding [GO:0003723]; mRNA catabolic process [GO:0006402]	cytosol [GO:0005829]; enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]	mRNA catabolic process [GO:0006402]	DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]	cytosol [GO:0005829]	cytosol [GO:0005829]	3'-5' exonuclease activity [GO:0008408]; exoribonuclease II activity [GO:0008859]; RNA binding [GO:0003723]	enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]
d2ix1a2_d5n8aa1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; 3'-5' exonuclease activity [GO:0008408]; exoribonuclease II activity [GO:0008859]; RNA binding [GO:0003723]; mRNA catabolic process [GO:0006402]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]; damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	mRNA catabolic process [GO:0006402]	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	cytosol [GO:0005829]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]	3'-5' exonuclease activity [GO:0008408]; exoribonuclease II activity [GO:0008859]; RNA binding [GO:0003723]	damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]
d2ix2b1_d3v60b1__1		Fungi	Crenarchaeota	Ascomycota	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	PCNA complex [GO:0043626]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]
d2ix2b2_d4n9aa3__1			Crenarchaeota	Proteobacteria	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	PCNA complex [GO:0043626]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d2ix2b2_d4tr8b2__1			Crenarchaeota	Proteobacteria	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA strand elongation involved in DNA replication [GO:0006271]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	DNA strand elongation involved in DNA replication [GO:0006271]	PCNA complex [GO:0043626]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d2ix4b2_d2wggd1__1	Viridiplantae		Streptophyta	Actinobacteria	mitochondrion [GO:0005739]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; thylakoid membrane organization [GO:0010027]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]; thylakoid membrane organization [GO:0010027]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	mitochondrion [GO:0005739]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]
d2ixcb__d1pmia___1		Fungi	Actinobacteria	Ascomycota	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]	cytosol [GO:0005829]; mannose-6-phosphate isomerase activity [GO:0004476]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; cell wall mannoprotein biosynthetic process [GO:0000032]; fungal-type cell wall organization [GO:0031505]; GDP-mannose biosynthetic process [GO:0009298]; protein glycosylation [GO:0006486]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]	carbohydrate metabolic process [GO:0005975]; cell wall mannoprotein biosynthetic process [GO:0000032]; fungal-type cell wall organization [GO:0031505]; GDP-mannose biosynthetic process [GO:0009298]; protein glycosylation [GO:0006486]		cytosol [GO:0005829]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	mannose-6-phosphate isomerase activity [GO:0004476]; zinc ion binding [GO:0008270]
d2ixcc__d5v00a___1			Actinobacteria	Proteobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]				dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	
d2ixhb2_d2ixcd___1			Proteobacteria	Actinobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]			dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d2ixhb2_d4xeta___1		Metazoa	Proteobacteria	Chordata	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cysteine metabolic process [GO:0006534]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]		cytosol [GO:0005829]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d2ixib__d2paka1__1			Proteobacteria	Firmicutes	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	isomerase activity [GO:0016853]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]				dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	isomerase activity [GO:0016853]
d2ixka__d2pa7a1__1			Proteobacteria	Firmicutes	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	isomerase activity [GO:0016853]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]				dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	isomerase activity [GO:0016853]
d2ixkb__d1dzra___1			Proteobacteria	Proteobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]			dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d2ixkb__d4uxah___1			Proteobacteria	Acidobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]	metal ion binding [GO:0046872]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; lipopolysaccharide core region biosynthetic process [GO:0009244]				dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	metal ion binding [GO:0046872]
d2ixlb__d1dztb___1			Firmicutes	Proteobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]			dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d2ixld__d4uxam___1			Firmicutes	Acidobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	metal ion binding [GO:0046872]					dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	metal ion binding [GO:0046872]
d2ixta__d1ot5b2__1		Fungi	Firmicutes	Ascomycota	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]		peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]		fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2ixva2_d1hjsa___1		Fungi		Ascomycota	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]; cell wall macromolecule catabolic process [GO:0016998]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]			lysozyme activity [GO:0003796]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]
d2ixva2_d2ixua2__1					lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]			lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2iy4c__d1z6oo___1		Metazoa	Firmicutes	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2iy4e__d2x17i___1			Firmicutes	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d2iy4h__d5lbhf___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2iy4k__d3r2sa___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2iy4l__d2jd80___1			Firmicutes	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d2iy4o__d3rgdw___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2iy4r__d1afre___1		Viridiplantae	Firmicutes	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]; cytoplasm [GO:0005737]	chloroplast [GO:0009507]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d2iy4s__d5xhna___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2iy4t__d4cvra___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2iy4u__d2v15l___1			Firmicutes	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d2iy4v__d4m1fa___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2iy4x__d3oj5v___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d2iy6a__d3jz4d___1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	cytoplasm [GO:0005737]; NADP binding [GO:0050661]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; gamma-aminobutyric acid catabolic process [GO:0009450]; nitrogen compound metabolic process [GO:0006807]		gamma-aminobutyric acid catabolic process [GO:0009450]; nitrogen compound metabolic process [GO:0006807]		cytoplasm [GO:0005737]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	NADP binding [GO:0050661]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]
d2iy6b__d2w8na___1		Metazoa	Deinococcus-Thermus	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein homodimerization activity [GO:0042803]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; acetate metabolic process [GO:0006083]; central nervous system development [GO:0007417]; galactosylceramide metabolic process [GO:0006681]; gamma-aminobutyric acid catabolic process [GO:0009450]; glucose metabolic process [GO:0006006]; glutamate metabolic process [GO:0006536]; glutamine metabolic process [GO:0006541]; glutathione metabolic process [GO:0006749]; glycerophospholipid metabolic process [GO:0006650]; neurotransmitter catabolic process [GO:0042135]; post-embryonic development [GO:0009791]; protein homotetramerization [GO:0051289]; respiratory electron transport chain [GO:0022904]; short-chain fatty acid metabolic process [GO:0046459]; succinate metabolic process [GO:0006105]		acetate metabolic process [GO:0006083]; central nervous system development [GO:0007417]; galactosylceramide metabolic process [GO:0006681]; gamma-aminobutyric acid catabolic process [GO:0009450]; glucose metabolic process [GO:0006006]; glutamate metabolic process [GO:0006536]; glutamine metabolic process [GO:0006541]; glutathione metabolic process [GO:0006749]; glycerophospholipid metabolic process [GO:0006650]; neurotransmitter catabolic process [GO:0042135]; post-embryonic development [GO:0009791]; protein homotetramerization [GO:0051289]; respiratory electron transport chain [GO:0022904]; short-chain fatty acid metabolic process [GO:0046459]; succinate metabolic process [GO:0006105]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	protein homodimerization activity [GO:0042803]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]
d2iybb__d1v61a1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; negative regulation of cell population proliferation [GO:0008285]	cell-cell junction [GO:0005911]; lamellipodium [GO:0030027]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; regulation of Rho protein signal transduction [GO:0035023]	negative regulation of cell population proliferation [GO:0008285]	intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; regulation of Rho protein signal transduction [GO:0035023]	cell junction [GO:0030054]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cell-cell junction [GO:0005911]; lamellipodium [GO:0030027]	cadherin binding [GO:0045296]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	Rho guanyl-nucleotide exchange factor activity [GO:0005089]
d2iybc__d1p3rb___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; negative regulation of cell population proliferation [GO:0008285]	apical plasma membrane [GO:0016324]; clathrin coat of coated pit [GO:0030132]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]; activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	negative regulation of cell population proliferation [GO:0008285]	activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	cell junction [GO:0030054]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	apical plasma membrane [GO:0016324]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol binding [GO:0035091]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]
d2iygb__d3toqa___1		Metazoa	Proteobacteria	Chordata	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	acylphosphatase activity [GO:0003998]; phosphate-containing compound metabolic process [GO:0006796]		phosphate-containing compound metabolic process [GO:0006796]			blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	acylphosphatase activity [GO:0003998]
d2iyoa2_d4xdza2__1			Firmicutes	Crenarchaeota	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]			NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]
d2iypa2_d1f14a1__1		Metazoa	Firmicutes	Chordata	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d2iysa__d1iqpe2__1			Actinobacteria	Euryarchaeota	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	cytosol [GO:0005829]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]
d2iz1a2_d4pzdb2__1			Firmicutes	Proteobacteria	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	fatty acid metabolic process [GO:0006631]			NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d2izaa__d3x00a1__1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2izaa__d4bj8b___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2izdd__d2c1sb___1			Actinobacteria		extracellular region [GO:0005576]; biotin binding [GO:0009374]				extracellular region [GO:0005576]		biotin binding [GO:0009374]	
d2izfb__d1kl5b___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2izfd__d1n9mc___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2izhb__d1y53y1__1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2iznb__d1frsc___1					T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	regulation of translation [GO:0006417]	T=3 icosahedral viral capsid [GO:0039617]	T=3 icosahedral viral capsid [GO:0039617]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2izob2_d3ifvc2__1			Crenarchaeota	Euryarchaeota	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; flap endonuclease activity [GO:0048256]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]			5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; flap endonuclease activity [GO:0048256]; magnesium ion binding [GO:0000287]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d2izpb__d4d3ed___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d2izva2_d1fyrc___1	Metazoa	Metazoa	Chordata	Chordata	phosphatidylinositol 3-kinase complex [GO:0005942]; 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; intracellular signal transduction [GO:0035556]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; regulation of growth [GO:0040008]	basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; hepatocyte growth factor-activated receptor activity [GO:0005008]; identical protein binding [GO:0042802]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; semaphorin receptor activity [GO:0017154]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; branching morphogenesis of an epithelial tube [GO:0048754]; cell surface receptor signaling pathway [GO:0007166]; endothelial cell morphogenesis [GO:0001886]; entry of bacterium into host cell [GO:0035635]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of autophagy [GO:0010507]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	intracellular signal transduction [GO:0035556]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; regulation of growth [GO:0040008]	branching morphogenesis of an epithelial tube [GO:0048754]; cell surface receptor signaling pathway [GO:0007166]; endothelial cell morphogenesis [GO:0001886]; entry of bacterium into host cell [GO:0035635]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of autophagy [GO:0010507]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	phosphatidylinositol 3-kinase complex [GO:0005942]	basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]	ATP binding [GO:0005524]; hepatocyte growth factor-activated receptor activity [GO:0005008]; identical protein binding [GO:0042802]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; semaphorin receptor activity [GO:0017154]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2izwb__d2fz1b___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	T=3 icosahedral viral capsid [GO:0039617]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d2izwc__d2hwc.1__1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2izza1_d3bxxa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]; anthocyanin-containing compound biosynthetic process [GO:0009718]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	anthocyanin-containing compound biosynthetic process [GO:0009718]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]
d2izza2_d1np3b1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	cytosol [GO:0005829]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]
d2izzb1_d2nu9f1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d2izzd1_d1r66a___1	Metazoa		Chordata	Actinobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]; nucleotide-sugar metabolic process [GO:0009225]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	nucleotide-sugar metabolic process [GO:0009225]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]	dTDP-glucose 4,6-dehydratase activity [GO:0008460]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2j00e1_d3d5ci1__1												
d2j00h1_d1seib___1				Firmicutes		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2j00p1_d3df1p1__1												
d2j00s1_d2qbhs1__1												
d2j01n1_d2qbgj1__1												
d2j01s1_d1xmqk___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2j02e1_d1vs7e1__1												
d2j03d1_d2qoxc1__1												
d2j03h2_d2aw4g1__1												
d2j03n1_d1n8rk___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2j03o1_d2qaok1__1												
d2j03p1_d2rdol1__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		ribosomal large subunit binding [GO:0043023]
d2j07a1_d1np7a1__1			Deinococcus-Thermus	Cyanobacteria	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	DNA binding [GO:0003677]; DNA photolyase activity [GO:0003913]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]			deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA photolyase activity [GO:0003913]
d2j07a1_d2wq6a2__1		Metazoa	Deinococcus-Thermus	Arthropoda	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	nucleotide binding [GO:0000166]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]				deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2j08a1_d3cvya2__1		Metazoa	Deinococcus-Thermus	Arthropoda	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	nucleotide binding [GO:0000166]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]				deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2j08a2_d3cvva1__1		Metazoa	Deinococcus-Thermus	Arthropoda	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	nucleotide binding [GO:0000166]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]				deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2j09a1_d4u8ha2__1		Metazoa	Deinococcus-Thermus	Chordata	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; histone deacetylase binding [GO:0042826]; histone methyltransferase binding [GO:1990226]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; pre-mRNA binding [GO:0036002]; RNA polymerase binding [GO:0070063]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription coactivator activity [GO:0003713]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; circadian regulation of gene expression [GO:0032922]; circadian regulation of translation [GO:0097167]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; fatty acid metabolic process [GO:0006631]; gluconeogenesis [GO:0006094]; glycogen biosynthetic process [GO:0005978]; histone H3 deacetylation [GO:0070932]; lactate biosynthetic process [GO:0019249]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription, termination [GO:0060567]; negative regulation of fat cell proliferation [GO:0070345]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051946]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of vasoconstriction [GO:0019229]; response to ischemia [GO:0002931]; response to light stimulus [GO:0009416]; white fat cell differentiation [GO:0050872]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	circadian regulation of gene expression [GO:0032922]; circadian regulation of translation [GO:0097167]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; fatty acid metabolic process [GO:0006631]; gluconeogenesis [GO:0006094]; glycogen biosynthetic process [GO:0005978]; histone H3 deacetylation [GO:0070932]; lactate biosynthetic process [GO:0019249]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription, termination [GO:0060567]; negative regulation of fat cell proliferation [GO:0070345]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of glutamate uptake involved in transmission of nerve impulse [GO:0051946]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of vasoconstriction [GO:0019229]; response to ischemia [GO:0002931]; response to light stimulus [GO:0009416]; white fat cell differentiation [GO:0050872]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	histone deacetylase binding [GO:0042826]; histone methyltransferase binding [GO:1990226]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; pre-mRNA binding [GO:0036002]; RNA polymerase binding [GO:0070063]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription coactivator activity [GO:0003713]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2j09a2_d4mlpd1__1		Metazoa	Deinococcus-Thermus	Chordata	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; FAD binding [GO:0071949]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; phosphatase binding [GO:0019902]; photoreceptor activity [GO:0009881]; protein kinase binding [GO:0019901]; single-stranded DNA binding [GO:0003697]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; protein import into nucleus [GO:0006606]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-chromophore linkage [GO:0018298]; protein import into nucleus [GO:0006606]; regulation of circadian rhythm [GO:0042752]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; FAD binding [GO:0071949]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; phosphatase binding [GO:0019902]; photoreceptor activity [GO:0009881]; protein kinase binding [GO:0019901]; single-stranded DNA binding [GO:0003697]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2j0gd__d1fzge1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j0ge__d1fzdc___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein-containing complex assembly [GO:0065003]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein polymerization [GO:0051258]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j0ha__d1rf0e1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j0hd__d1fzcf1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j0he__d2fiba___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j0ob__d2ym9c___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d2j0qa2_d5e4fb1__1	Metazoa		Chordata		catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]	actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2j0sd__d2dnka1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; BRE binding [GO:0042835]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; alternative mRNA splicing, via spliceosome [GO:0000380]; embryo development ending in birth or egg hatching [GO:0009792]; germ cell development [GO:0007281]; in utero embryonic development [GO:0001701]; mRNA splice site selection [GO:0006376]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of retina development in camera-type eye [GO:1902866]	mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]	alternative mRNA splicing, via spliceosome [GO:0000380]; embryo development ending in birth or egg hatching [GO:0009792]; germ cell development [GO:0007281]; in utero embryonic development [GO:0001701]; mRNA splice site selection [GO:0006376]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of retina development in camera-type eye [GO:1902866]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	BRE binding [GO:0042835]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d2j0te__d1xwea1__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; metalloendopeptidase inhibitor activity [GO:0008191]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; zinc ion binding [GO:0008270]; aging [GO:0007568]; cartilage development [GO:0051216]; cell activation [GO:0001775]; cellular protein metabolic process [GO:0044267]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of trophoblast cell migration [GO:1901164]; platelet degranulation [GO:0002576]; positive regulation of cell population proliferation [GO:0008284]; post-translational protein modification [GO:0043687]; regulation of integrin-mediated signaling pathway [GO:2001044]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to organic substance [GO:0010033]; response to peptide hormone [GO:0043434]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	aging [GO:0007568]; cartilage development [GO:0051216]; cell activation [GO:0001775]; cellular protein metabolic process [GO:0044267]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of trophoblast cell migration [GO:1901164]; platelet degranulation [GO:0002576]; positive regulation of cell population proliferation [GO:0008284]; post-translational protein modification [GO:0043687]; regulation of integrin-mediated signaling pathway [GO:2001044]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to organic substance [GO:0010033]; response to peptide hormone [GO:0043434]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	basement membrane [GO:0005604]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; metalloendopeptidase inhibitor activity [GO:0008191]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; zinc ion binding [GO:0008270]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d2j0tf__d3cu7af__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; metalloendopeptidase inhibitor activity [GO:0008191]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; zinc ion binding [GO:0008270]; aging [GO:0007568]; cartilage development [GO:0051216]; cell activation [GO:0001775]; cellular protein metabolic process [GO:0044267]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of trophoblast cell migration [GO:1901164]; platelet degranulation [GO:0002576]; positive regulation of cell population proliferation [GO:0008284]; post-translational protein modification [GO:0043687]; regulation of integrin-mediated signaling pathway [GO:2001044]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to organic substance [GO:0010033]; response to peptide hormone [GO:0043434]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	aging [GO:0007568]; cartilage development [GO:0051216]; cell activation [GO:0001775]; cellular protein metabolic process [GO:0044267]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of trophoblast cell migration [GO:1901164]; platelet degranulation [GO:0002576]; positive regulation of cell population proliferation [GO:0008284]; post-translational protein modification [GO:0043687]; regulation of integrin-mediated signaling pathway [GO:2001044]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to organic substance [GO:0010033]; response to peptide hormone [GO:0043434]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	basement membrane [GO:0005604]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; metalloendopeptidase inhibitor activity [GO:0008191]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; zinc ion binding [GO:0008270]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d2j0ua1_d2bekd___1	Metazoa		Chordata	Deinococcus-Thermus	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; U2-type catalytic step 1 spliceosome [GO:0071006]; ATP binding [GO:0005524]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA stem-loop binding [GO:0035613]; selenocysteine insertion sequence binding [GO:0035368]; translation regulator activity [GO:0045182]; associative learning [GO:0008306]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to selenite ion [GO:0072715]; embryonic cranial skeleton morphogenesis [GO:0048701]; exploration behavior [GO:0035640]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of selenocysteine incorporation [GO:1904570]; negative regulation of selenocysteine insertion sequence binding [GO:1904574]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; response to organic cyclic compound [GO:0014070]; RNA export from nucleus [GO:0006405]; rRNA processing [GO:0006364]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]; chromosome segregation [GO:0007059]	associative learning [GO:0008306]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to selenite ion [GO:0072715]; embryonic cranial skeleton morphogenesis [GO:0048701]; exploration behavior [GO:0035640]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of selenocysteine incorporation [GO:1904570]; negative regulation of selenocysteine insertion sequence binding [GO:1904574]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; response to organic cyclic compound [GO:0014070]; RNA export from nucleus [GO:0006405]; rRNA processing [GO:0006364]	chromosome segregation [GO:0007059]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; U2-type catalytic step 1 spliceosome [GO:0071006]		ATP binding [GO:0005524]; mRNA binding [GO:0003729]; poly(A) binding [GO:0008143]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA stem-loop binding [GO:0035613]; selenocysteine insertion sequence binding [GO:0035368]; translation regulator activity [GO:0045182]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]
d2j0xa1_d2btya1__1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]; homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]	acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]
d2j0yb__d1re4b1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j0yc__d1lwuh1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	fibrinogen complex [GO:0005577]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]
d2j0yf__d1lt9f1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j16b__d3a5ka___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; MAP kinase tyrosine phosphatase activity [GO:0033550]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion [GO:0000754]; cell wall integrity MAPK cascade [GO:0000196]; inactivation of MAPK activity [GO:0000188]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]; regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0010969]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion [GO:0000754]; cell wall integrity MAPK cascade [GO:0000196]; inactivation of MAPK activity [GO:0000188]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]; regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0010969]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; MAP kinase tyrosine phosphatase activity [GO:0033550]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2j1gb__d1n8ec1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j1gc__d1lt9e1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j1gd__d1fzdg___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein-containing complex assembly [GO:0065003]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein polymerization [GO:0051258]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j1gf__d1fzdh___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein-containing complex assembly [GO:0065003]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein polymerization [GO:0051258]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular vesicle [GO:1903561]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; synapse [GO:0045202]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j1ka__d5szfl1__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2j1kd__d2oj5b2__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	viral outer capsid [GO:0039624]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	viral outer capsid [GO:0039624]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2j1kg__d4f2mb2__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2j1ki__d3da0c2__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	virus tail, baseplate [GO:0098025]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2j1km__d3u6xm2__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	virus tail, baseplate [GO:0098025]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2j1kn__d4k6wa___1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	viral capsid [GO:0019028]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	metal ion binding [GO:0046872]
d2j1kq__d3bq4g___1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	viral capsid [GO:0019028]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2j1kr__d4hepa2__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	virus tail, baseplate [GO:0098025]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2j1ks__d1h7zc___1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2j1kt__d1a6vj___1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2j1kv__d1oazj___1	Metazoa		Chordata	Proteobacteria	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2j1kv__d1wbxb___1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2j1kx__d5b8cj___1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2j1ky__d4uimb1__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2j1kz__d1r3ka2__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2j1kz__d4x7fd1__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2j1ra__d1ryyc1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	carbohydrate metabolic process [GO:0005975]				metal ion binding [GO:0046872]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d2j1rb__d3k77a___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	carbohydrate metabolic process [GO:0005975]	base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]		ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	metal ion binding [GO:0046872]	3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]
d2j1sa__d1p8jg1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	carbohydrate metabolic process [GO:0005975]	dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]	metal ion binding [GO:0046872]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d2j1sb__d3t0bc1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2j1ua__d1jz3d3__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2j1ub__d1jyxa3__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2j1ub__d3heie___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	carbohydrate metabolic process [GO:0005975]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]		cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	metal ion binding [GO:0046872]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]
d2j1vb__d4arya3__1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	carbohydrate metabolic process [GO:0005975]	sporulation resulting in formation of a cellular spore [GO:0030435]			metal ion binding [GO:0046872]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d2j1wb__d3wtya___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]
d2j22a__d3iaqd1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2j23a1_d1o73a___1	Fungi		Basidiomycota		cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]	cell [GO:0005623]	protein disulfide oxidoreductase activity [GO:0015035]	
d2j25b2_d1qoxb___1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	cellulose catabolic process [GO:0030245]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d2j28f1_d3d7aa___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]		5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]	
d2j28t1_d1k8at___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	translation [GO:0006412]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]	ribosome [GO:0005840]	5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2j28t1_d1s72m___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	translation [GO:0006412]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]	ribosome [GO:0005840]	5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2j28v1_d5bnza2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]	cytosol [GO:0005829]	5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]	ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]
d2j2fc__d1oqbb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d2j2fd__d3kx9p___1	Viridiplantae		Streptophyta	Euryarchaeota	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	chloroplast [GO:0009507]	cell [GO:0005623]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]
d2j2jd__d2oj5e1__1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	viral outer capsid [GO:0039624]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	viral outer capsid [GO:0039624]		
d2j2pa__d1re4c1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j2pc__d1n73b1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	fibrinogen complex [GO:0005577]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]
d2j2pe__d4jzca___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]
d2j2za2_d1klfa2__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	outer membrane-bounded periplasmic space [GO:0030288]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d2j3fb__d1fida___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j3fc__d1rf1e1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j3fe__d3fiba___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j3ff__d1fzgf1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j3ga__d1m1jb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	fibrinogen complex [GO:0005577]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor binding [GO:0005102]
d2j3ge__d1m1jc1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	fibrinogen complex [GO:0005577]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor binding [GO:0005102]
d2j3gf__d1re3e1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j3gf__d2j3fd___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d2j3oc__d1fzgc1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j3oe__d1re3c1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j3pa__d1p63a___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2j3sa1_d1svba1__1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2j3sa3_d1vfob1__1	Metazoa		Chordata	Firmicutes	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	carbohydrate metabolic process [GO:0005975]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2j3sa3_d2gixa1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	dendrite [GO:0030425]; dendritic spine [GO:0043197]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; intrinsic component of membrane [GO:0031224]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cellular response to mechanical stimulus [GO:0071260]; magnesium ion transport [GO:0015693]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of skeletal muscle contraction via regulation of action potential [GO:0014861]; relaxation of cardiac muscle [GO:0055119]; relaxation of skeletal muscle [GO:0090076]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cellular response to mechanical stimulus [GO:0071260]; magnesium ion transport [GO:0015693]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of skeletal muscle contraction via regulation of action potential [GO:0014861]; relaxation of cardiac muscle [GO:0055119]; relaxation of skeletal muscle [GO:0090076]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	dendrite [GO:0030425]; dendritic spine [GO:0043197]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; intrinsic component of membrane [GO:0031224]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; voltage-gated potassium channel complex [GO:0008076]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]
d2j3sb1_d2c9pb___1	Metazoa		Chordata	Proteobacteria	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	periplasmic space [GO:0042597]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	copper ion binding [GO:0005507]
d2j3sb3_d2bq9b2__1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]		actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]		actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	
d2j3ua__d1fzgb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j3ua__d4r9ta___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d2j3uf__d1re3f1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j3wa__d4neel___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; TRAPP complex [GO:0030008]; ion channel binding [GO:0044325]; transcription factor binding [GO:0008134]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; regulation of transcription, DNA-templated [GO:0006355]; skeletal system development [GO:0001501]	AP-2 adaptor complex [GO:0030122]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]; clathrin adaptor activity [GO:0035615]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]	endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; regulation of transcription, DNA-templated [GO:0006355]; skeletal system development [GO:0001501]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; TRAPP complex [GO:0030008]	AP-2 adaptor complex [GO:0030122]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]	ion channel binding [GO:0044325]; transcription factor binding [GO:0008134]	clathrin adaptor activity [GO:0035615]; phosphatidylinositol binding [GO:0035091]; protein-containing complex binding [GO:0044877]
d2j3wf__d5jrxa___1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; TRAPP complex [GO:0030008]; ion channel binding [GO:0044325]; transcription factor binding [GO:0008134]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; regulation of transcription, DNA-templated [GO:0006355]; skeletal system development [GO:0001501]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; regulation of transcription, DNA-templated [GO:0006355]; skeletal system development [GO:0001501]	signal transduction [GO:0007165]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; TRAPP complex [GO:0030008]	integral component of membrane [GO:0016021]	ion channel binding [GO:0044325]; transcription factor binding [GO:0008134]	heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2j3zb2_d1wokd2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]		DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2j3zb2_d4h0xa2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	pathogenesis [GO:0009405]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	extracellular region [GO:0005576]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2j3zd2_d4r6ea2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]		DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2j3ze1_d5wu0a1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		nucleotide binding [GO:0000166]
d2j3zf1_d1ojqa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		nucleotide binding [GO:0000166]; transferase activity, transferring pentosyl groups [GO:0016763]
d2j3zf1_d4pjtc2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]		DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2j43b2_d1uksb2__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; pullulanase activity [GO:0051060]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2j46b2_d2yhsa2__1			Deinococcus-Thermus	Proteobacteria	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; signal recognition particle binding [GO:0005047]; protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; signal recognition particle binding [GO:0005047]
d2j47a2_d1bgmj5__1			Bacteroidetes		[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]		carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]				[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]	
d2j4ee__d2e5xa___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; dITP diphosphatase activity [GO:0035870]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; chromosome organization [GO:0051276]; deoxyribonucleoside triphosphate catabolic process [GO:0009204]; ITP catabolic process [GO:0006193]; nucleoside triphosphate catabolic process [GO:0009143]; purine nucleotide catabolic process [GO:0006195]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	chromosome organization [GO:0051276]; deoxyribonucleoside triphosphate catabolic process [GO:0009204]; ITP catabolic process [GO:0006193]; nucleoside triphosphate catabolic process [GO:0009143]; purine nucleotide catabolic process [GO:0006195]	nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]		dITP diphosphatase activity [GO:0035870]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]
d2j4ef__d1u5wf2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; dITP diphosphatase activity [GO:0035870]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; chromosome organization [GO:0051276]; deoxyribonucleoside triphosphate catabolic process [GO:0009204]; ITP catabolic process [GO:0006193]; nucleoside triphosphate catabolic process [GO:0009143]; purine nucleotide catabolic process [GO:0006195]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleotide binding [GO:0000166]; nucleotide metabolic process [GO:0009117]; response to antibiotic [GO:0046677]; thiamine metabolic process [GO:0006772]	chromosome organization [GO:0051276]; deoxyribonucleoside triphosphate catabolic process [GO:0009204]; ITP catabolic process [GO:0006193]; nucleoside triphosphate catabolic process [GO:0009143]; purine nucleotide catabolic process [GO:0006195]	nucleotide metabolic process [GO:0009117]; response to antibiotic [GO:0046677]; thiamine metabolic process [GO:0006772]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]		dITP diphosphatase activity [GO:0035870]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleotide binding [GO:0000166]
d2j4ga1_d2xpka3__1			Bacteroidetes	Firmicutes	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d2j4rb2_d3ldob1__1		Metazoa	Aquificae	Chordata	metal ion binding [GO:0046872]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]		ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	metal ion binding [GO:0046872]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d2j4wh1_d43c9h___1		Metazoa	Apicomplexa	Chordata	membrane [GO:0016020]; pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	pathogenesis [GO:0009405]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	membrane [GO:0016020]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2j4wh2_d4hafa2__1		Metazoa	Apicomplexa	Chordata	membrane [GO:0016020]; pathogenesis [GO:0009405]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	pathogenesis [GO:0009405]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	membrane [GO:0016020]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2j55a__d1uria___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2j56a__d3n2jh___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2j56b__d3fu7b3__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2j57a__d2yxwb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d2j57b__d4n26a1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; chromatin-mediated maintenance of transcription [GO:0048096]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]		cellular response to leukemia inhibitory factor [GO:1990830]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin organization [GO:0006325]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]	periplasmic space [GO:0042597]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]
d2j57c__d2i7sb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2j57g__d1mg2e___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2j57j__d1mg2m___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2j59c2_d4d0na___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; GTPase activator activity [GO:0005096]; establishment of Golgi localization [GO:0051683]; Golgi organization [GO:0007030]; maintenance of Golgi location [GO:0051684]; organelle transport along microtubule [GO:0072384]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	actin filament [GO:0005884]; cell cortex [GO:0005938]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; cAMP-dependent protein kinase activity [GO:0004691]; MAP-kinase scaffold activity [GO:0005078]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; protein kinase A binding [GO:0051018]; Rho GTPase binding [GO:0017048]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of glucocorticoid mediated signaling pathway [GO:1900169]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056]	establishment of Golgi localization [GO:0051683]; Golgi organization [GO:0007030]; maintenance of Golgi location [GO:0051684]; organelle transport along microtubule [GO:0072384]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of glucocorticoid mediated signaling pathway [GO:1900169]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]	actin filament [GO:0005884]; cell cortex [GO:0005938]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	GTPase activator activity [GO:0005096]	cAMP-dependent protein kinase activity [GO:0004691]; MAP-kinase scaffold activity [GO:0005078]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; protein kinase A binding [GO:0051018]; Rho GTPase binding [GO:0017048]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]
d2j59f2_d4d6ca1__1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; GTPase activator activity [GO:0005096]; establishment of Golgi localization [GO:0051683]; Golgi organization [GO:0007030]; maintenance of Golgi location [GO:0051684]; organelle transport along microtubule [GO:0072384]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]		establishment of Golgi localization [GO:0051683]; Golgi organization [GO:0007030]; maintenance of Golgi location [GO:0051684]; organelle transport along microtubule [GO:0072384]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]		actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]		GTPase activator activity [GO:0005096]	
d2j5ga__d1yg8b___1			Cyanobacteria	Proteobacteria	catalytic activity [GO:0003824]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	catalytic activity [GO:0003824]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2j5gb__d2qq3k___1			Cyanobacteria	Firmicutes	catalytic activity [GO:0003824]	catalytic activity [GO:0003824]					catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d2j5gc__d2zl4j___1			Cyanobacteria	Proteobacteria	catalytic activity [GO:0003824]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	catalytic activity [GO:0003824]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d2j5gd__d3qkac1__1			Cyanobacteria	Actinobacteria	catalytic activity [GO:0003824]	catalytic activity [GO:0003824]					catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d2j5ge__d2zl2g___1			Cyanobacteria	Proteobacteria	catalytic activity [GO:0003824]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	catalytic activity [GO:0003824]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d2j5ge__d4izca___1			Cyanobacteria	Proteobacteria	catalytic activity [GO:0003824]	hydro-lyase activity [GO:0016836]; protein hexamerization [GO:0034214]		protein hexamerization [GO:0034214]			catalytic activity [GO:0003824]	hydro-lyase activity [GO:0016836]
d2j5gl__d1dubc___1		Metazoa	Cyanobacteria	Chordata	catalytic activity [GO:0003824]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation [GO:0006635]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]
d2j5ic__d5e0sc___1			Proteobacteria	Actinobacteria	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; plasma membrane [GO:0005886]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; plasma membrane [GO:0005886]	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d2j5ig__d5e0sf___1			Proteobacteria	Actinobacteria	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; plasma membrane [GO:0005886]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; plasma membrane [GO:0005886]	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d2j5ih__d2zl4c___1			Proteobacteria	Proteobacteria	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d2j5ij__d3q0je___1			Proteobacteria	Actinobacteria	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	cell wall [GO:0005618]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation [GO:0006635]		cell wall [GO:0005618]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]
d2j5il__d2j5gl___1			Proteobacteria	Cyanobacteria	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	catalytic activity [GO:0003824]					trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	catalytic activity [GO:0003824]
d2j5ka2_d3tl2a2__1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	L-malate dehydrogenase activity [GO:0030060]; malic enzyme activity [GO:0004470]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]		L-malate dehydrogenase activity [GO:0030060]	L-malate dehydrogenase activity [GO:0030060]; malic enzyme activity [GO:0004470]
d2j5kc1_d4kuhg1__1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]		L-malate dehydrogenase activity [GO:0030060]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]
d2j5kc2_d1pzgb2__1			Euryarchaeota	Apicomplexa	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]		L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d2j5kc2_d3u95b2__1			Euryarchaeota	Thermotogae	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		L-malate dehydrogenase activity [GO:0030060]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d2j5kd2_d3wswa2__1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d2j5lb1_d1a7ql___1		Metazoa	Apicomplexa	Chordata	membrane [GO:0016020]; pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	pathogenesis [GO:0009405]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	membrane [GO:0016020]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2j5lb2_d3o3ae1__1		Metazoa	Apicomplexa	Chordata	membrane [GO:0016020]; pathogenesis [GO:0009405]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	pathogenesis [GO:0009405]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	membrane [GO:0016020]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2j5lb2_d4f3fa1__1		Metazoa	Apicomplexa	Chordata	membrane [GO:0016020]; pathogenesis [GO:0009405]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; pancreas development [GO:0031016]; post-translational protein modification [GO:0043687]	pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; pancreas development [GO:0031016]; post-translational protein modification [GO:0043687]	membrane [GO:0016020]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]		
d2j5lc1_d1um4l2__1		Metazoa	Apicomplexa	Chordata	membrane [GO:0016020]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		membrane [GO:0016020]			
d2j5lc2_d2vxum2__1			Apicomplexa		membrane [GO:0016020]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		membrane [GO:0016020]			
d2j5lc2_d4pozc1__1			Apicomplexa		membrane [GO:0016020]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		membrane [GO:0016020]			
d2j5qa1_d1zo8c___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]		L-malate dehydrogenase activity [GO:0030060]	
d2j5qc1_d3qwic___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]		L-malate dehydrogenase activity [GO:0030060]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2j5rc1_d3vpha1__1			Euryarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d2j5rd2_d4ajjc2__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2j5wa1_d1npjb1__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2j5wa2_d5f7aa1__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2j5wa4_d1as7a1__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2j5wa6_d4pcya___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	chloroplast thylakoid membrane [GO:0009535]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2j5za__d2j1gb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d2j5zb__d1fzbc1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j60c__d2jhkf___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]; cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]
d2j61b__d1fzac1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j62b2_d1dp0a5__1			Firmicutes	Proteobacteria	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2j62b2_d2chob2__1			Firmicutes	Bacteroidetes	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]
d2j62b3_d2gk1.2__1		Metazoa	Firmicutes	Chordata	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]		acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d2j64a__d1rf0b1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j64b__d2j1gf___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d2j64c__d1n86c1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2j64c__d2j3ub___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; recognition of apoptotic cell [GO:0043654]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	antigen binding [GO:0003823]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d2j65b2_d4qnja1__1		Viridiplantae	Aquificae	Streptophyta	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	lipid A biosynthetic process [GO:0009245]	histidine biosynthetic process [GO:0000105]		chloroplast [GO:0009507]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2j6ea2_d5wk3v2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR4 chemokine receptor binding [GO:0031729]; chemokine activity [GO:0008009]; signaling receptor binding [GO:0005102]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; multicellular organism development [GO:0007275]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil chemotaxis [GO:0030593]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; multicellular organism development [GO:0007275]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil chemotaxis [GO:0030593]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	CCR4 chemokine receptor binding [GO:0031729]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; signaling receptor binding [GO:0005102]
d2j6eh1_d5o2ub___1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; viral budding via host ESCRT complex [GO:0039702]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	viral budding via host ESCRT complex [GO:0039702]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2j6ei1_d1q1jl2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d2j6el1_d2vc2l2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2j6em1_d5y11b2__1	Metazoa		Chordata	Negarnaviricota	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; virion [GO:0019012]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]; virion [GO:0019012]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2j6em2_d4ba8a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor complex [GO:0019815]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; immunoglobulin receptor binding [GO:0034987]; transmembrane signaling receptor activity [GO:0004888]; activation of MAPK activity [GO:0000187]; antigen processing and presentation [GO:0019882]; B cell affinity maturation [GO:0002344]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; early endosome to late endosome transport [GO:0045022]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell morphogenesis [GO:0022604]; regulation of immunoglobulin production [GO:0002637]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	activation of MAPK activity [GO:0000187]; antigen processing and presentation [GO:0019882]; B cell affinity maturation [GO:0002344]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; early endosome to late endosome transport [GO:0045022]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell morphogenesis [GO:0022604]; regulation of immunoglobulin production [GO:0002637]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	B cell receptor complex [GO:0019815]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]; immunoglobulin receptor binding [GO:0034987]; transmembrane signaling receptor activity [GO:0004888]
d2j6hb1_d2o2ca___1			Proteobacteria		cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	glycosome [GO:0020015]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	glycosome [GO:0020015]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	glucose-6-phosphate isomerase activity [GO:0004347]
d2j6hb2_d3c92j1__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	proteasomal protein catabolic process [GO:0010498]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2j6la__d2eiia___1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]; cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2j6lb__d4nmjd___1	Metazoa		Chordata	Crenarchaeota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]; cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2j6ld__d4kwga___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]; cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2j6le__d2j5na___1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]; cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2j6lh__d1nzzg___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]; cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2j6lh__d5vbfa___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]; cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]	cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]	succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]
d2j6wa__d5aoja___1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d2j6xe__d3krua___1			Firmicutes	Firmicutes	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d2j6xg__d4jd4a___1			Firmicutes		FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d2j74a__d2pb1a___1		Fungi	Firmicutes	Ascomycota	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]; cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	metabolic process [GO:0008152]	cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]		cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]	cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]
d2j74b__d3vd4b3__1			Firmicutes	Proteobacteria	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	metabolic process [GO:0008152]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2j7ag__d1m1qa___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; denitrification pathway [GO:0019333]; oxidation-reduction process [GO:0055114]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	denitrification pathway [GO:0019333]; oxidation-reduction process [GO:0055114]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2j7pa1_d5l3va1__1			Deinococcus-Thermus	Crenarchaeota	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]	signal recognition particle [GO:0048500]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d2j7pe2_d1h8ec3__1		Metazoa	Deinococcus-Thermus	Chordata	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	ATP synthesis coupled proton transport [GO:0015986]	signal recognition particle [GO:0048500]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2j7qd__d2cr5a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	endoplasmic reticulum [GO:0005783]; integral component of endoplasmic reticulum membrane [GO:0030176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; ubiquitin-dependent ERAD pathway [GO:0030433]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	ubiquitin-dependent ERAD pathway [GO:0030433]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	endoplasmic reticulum [GO:0005783]; integral component of endoplasmic reticulum membrane [GO:0030176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	
d2j7zb__d4xdxa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; chemokine activity [GO:0008009]; chemokine receptor binding [GO:0042379]; CXCR chemokine receptor binding [GO:0045236]; growth factor activity [GO:0008083]; integrin binding [GO:0005178]; signaling receptor binding [GO:0005102]; adult locomotory behavior [GO:0008344]; animal organ regeneration [GO:0031100]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; axon guidance [GO:0007411]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cellular calcium ion homeostasis [GO:0006874]; cellular response to chemokine [GO:1990869]; chemokine (C-X-C motif) ligand 12 signaling pathway [GO:0038146]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; defense response [GO:0006952]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; integrin activation [GO:0033622]; killing of cells of other organism [GO:0031640]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of leukocyte tethering or rolling [GO:1903237]; neuron migration [GO:0001764]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell migration [GO:2000406]; regulation of actin polymerization or depolymerization [GO:0008064]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to peptide hormone [GO:0043434]; response to radiation [GO:0009314]; response to ultrasound [GO:1990478]; response to virus [GO:0009615]; signal transduction [GO:0007165]; T cell chemotaxis [GO:0010818]; telencephalon cell migration [GO:0022029]; viral process [GO:0016032]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; chemokine activity [GO:0008009]; interleukin-8 receptor binding [GO:0005153]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; calcium-mediated signaling [GO:0019722]; cell cycle arrest [GO:0007050]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; embryonic digestive tract development [GO:0048566]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of angiogenesis [GO:0045766]; positive regulation of neutrophil chemotaxis [GO:0090023]; receptor internalization [GO:0031623]; regulation of cell adhesion [GO:0030155]; regulation of entry of bacterium into host cell [GO:2000535]; regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045091]; response to endoplasmic reticulum stress [GO:0034976]; response to molecule of bacterial origin [GO:0002237]; signal transduction [GO:0007165]	adult locomotory behavior [GO:0008344]; animal organ regeneration [GO:0031100]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; axon guidance [GO:0007411]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cellular calcium ion homeostasis [GO:0006874]; cellular response to chemokine [GO:1990869]; chemokine (C-X-C motif) ligand 12 signaling pathway [GO:0038146]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; defense response [GO:0006952]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; integrin activation [GO:0033622]; killing of cells of other organism [GO:0031640]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of leukocyte tethering or rolling [GO:1903237]; neuron migration [GO:0001764]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell migration [GO:2000406]; regulation of actin polymerization or depolymerization [GO:0008064]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to peptide hormone [GO:0043434]; response to radiation [GO:0009314]; response to ultrasound [GO:1990478]; response to virus [GO:0009615]; signal transduction [GO:0007165]; T cell chemotaxis [GO:0010818]; telencephalon cell migration [GO:0022029]; viral process [GO:0016032]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; calcium-mediated signaling [GO:0019722]; cell cycle arrest [GO:0007050]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; embryonic digestive tract development [GO:0048566]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; killing of cells of other organism [GO:0031640]; leukocyte chemotaxis [GO:0030595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of angiogenesis [GO:0045766]; positive regulation of neutrophil chemotaxis [GO:0090023]; receptor internalization [GO:0031623]; regulation of cell adhesion [GO:0030155]; regulation of entry of bacterium into host cell [GO:2000535]; regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045091]; response to endoplasmic reticulum stress [GO:0034976]; response to molecule of bacterial origin [GO:0002237]; signal transduction [GO:0007165]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	chemokine activity [GO:0008009]; chemokine receptor binding [GO:0042379]; CXCR chemokine receptor binding [GO:0045236]; growth factor activity [GO:0008083]; integrin binding [GO:0005178]; signaling receptor binding [GO:0005102]	chemokine activity [GO:0008009]; interleukin-8 receptor binding [GO:0005153]
d2j88a__d1h2ja___1	Metazoa		Arthropoda	Firmicutes	extracellular region [GO:0005576]; hyalurononglucosaminidase activity [GO:0004415]; carbohydrate metabolic process [GO:0005975]; defense response [GO:0006952]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]; defense response [GO:0006952]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	hyalurononglucosaminidase activity [GO:0004415]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]
d2j8eb__d3cfya1__1				Proteobacteria		ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]		phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]				ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d2j8fa1_d1hcxa___1				Firmicutes	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; cell wall organization [GO:0071555]; establishment of competence for transformation [GO:0030420]; peptidoglycan catabolic process [GO:0009253]; sporulation resulting in formation of a cellular spore [GO:0030435]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall organization [GO:0071555]; establishment of competence for transformation [GO:0030420]; peptidoglycan catabolic process [GO:0009253]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]	lysozyme activity [GO:0003796]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]
d2j8fa2_d1jfxa___1				Actinobacteria	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		extracellular region [GO:0005576]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2j8fa2_d1jyva5__1				Proteobacteria	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	lysozyme activity [GO:0003796]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2j8ha1_d1lo4h1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	
d2j8ha2_d1orqb1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2j8ma__d4jlya___1			Proteobacteria	Proteobacteria	N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	cytoplasm [GO:0005737]; diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]; polyamine catabolic process [GO:0006598]		polyamine catabolic process [GO:0006598]		cytoplasm [GO:0005737]	N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]
d2j8mb__d4evyb___1			Proteobacteria	Proteobacteria	N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]			N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]
d2j8na__d1rxtb2__1		Metazoa	Proteobacteria	Chordata	N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]; cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]		cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]
d2j8nb__d4ufvb1__1			Proteobacteria	Apicomplexa	N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]		N-terminal protein myristoylation [GO:0006499]			N-acetyltransferase activity [GO:0008080]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d2j8ob2_d1afvm1__1	Metazoa		Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2j8ua2_d5d5mc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2j8uf2_d2o5yl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2j8uh1_d3cfda1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2j8ui2_d8fabc1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2j8um2_d3oj2d2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2j8wa__d2xlea___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2j8xa1_d4wrxa1__1				Actinobacteria		mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]		base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]		mitochondrion [GO:0005739]; nucleus [GO:0005634]		uracil DNA N-glycosylase activity [GO:0004844]
d2j94a__d3sjog___1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2j9aa1_d1gytg2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]		peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]
d2j9aa2_d1gyth1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]		peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]
d2j9ec1_d1qy7a___1			Euryarchaeota	Cyanobacteria	enzyme regulator activity [GO:0030234]; nucleotide binding [GO:0000166]; regulation of nitrogen utilization [GO:0006808]	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; regulation of nitrogen utilization [GO:0006808]	regulation of nitrogen utilization [GO:0006808]	regulation of nitrogen utilization [GO:0006808]			enzyme regulator activity [GO:0030234]; nucleotide binding [GO:0000166]	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d2j9fb1_d2ez9a3__1	Metazoa		Chordata	Firmicutes	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]		mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]		3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d2j9fd1_d1t9cb2__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2j9fd2_d1tkab3__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	pentose-phosphate shunt [GO:0006098]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d2j9ga2_d1jdbh3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2j9ga2_d2ys7a1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d2j9gb2_d1ez1a2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d2j9ha1_d4llrb___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2j9hb2_d2fheb1__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d2j9na__d1c5z.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d2ja5g1_d1g6pa___1	Fungi		Ascomycota	Thermotogae	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]		cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]
d2ja9a2_d1x4ma1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasmic exosome (RNase complex) [GO:0000177]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; ncRNA 3'-end processing [GO:0043628]; nonfunctional rRNA decay [GO:0070651]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; synapse [GO:0045202]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; developmental cell growth [GO:0048588]; hematopoietic stem cell proliferation [GO:0071425]; positive regulation of gene expression [GO:0010628]; positive regulation of Schwann cell migration [GO:1900149]; regulation of transcription by RNA polymerase II [GO:0006357]; somatic stem cell division [GO:0048103]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; ncRNA 3'-end processing [GO:0043628]; nonfunctional rRNA decay [GO:0070651]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	developmental cell growth [GO:0048588]; hematopoietic stem cell proliferation [GO:0071425]; positive regulation of gene expression [GO:0010628]; positive regulation of Schwann cell migration [GO:1900149]; regulation of transcription by RNA polymerase II [GO:0006357]; somatic stem cell division [GO:0048103]	cytoplasmic exosome (RNase complex) [GO:0000177]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; synapse [GO:0045202]	manganese ion binding [GO:0030145]; RNA binding [GO:0003723]	RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]
d2jalb__d1w9dm___1		Viridiplantae	Thermotogae	Streptophyta	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]		vacuole [GO:0005773]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]
d2japa__d1hwyf1__1		Metazoa	Actinobacteria	Chordata	nucleotide binding [GO:0000166]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d2jawa__d2r8xf___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	lipopolysaccharide biosynthetic process [GO:0009103]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d2jazc__d3gkld___1			Proteobacteria	Proteobacteria	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	extrachromosomal circular DNA [GO:0005727]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	bacteriocin immunity [GO:0030153]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]		extrachromosomal circular DNA [GO:0005727]	toxic substance binding [GO:0015643]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d2jb0a__d2gzia___1			Proteobacteria	Proteobacteria	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]		protein-containing complex [GO:0032991]	toxic substance binding [GO:0015643]	protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]
d2jb5h1_d1bbdl1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	immune response [GO:0006955]; immunoglobulin production [GO:0002377]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d2jb5l2_d5u2vf2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2jb6a1_d4lgrb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	endoplasmic reticulum [GO:0005783]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2jb6b2_d1u8ka2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2jb7a__d2ekmc___1			Crenarchaeota	Crenarchaeota	nucleotide binding [GO:0000166]						nucleotide binding [GO:0000166]	
d2jb9a__d1oxkf___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]; osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]
d2jb9a__d3ltem___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding [GO:0003677]
d2jb9b__d2vuib___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]	bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d2jc2b__d2le9c___1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]; action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d2jc2d__d3df0b___1	Metazoa	Metazoa	Chordata	Chordata	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]; action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; proteolysis [GO:0006508]	action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	proteolysis [GO:0006508]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]
d2jc3c__d3hmka___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; D-serine ammonia-lyase activity [GO:0008721]; glycine binding [GO:0016594]; L-serine ammonia-lyase activity [GO:0003941]; magnesium ion binding [GO:0000287]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; serine racemase activity [GO:0030378]; threonine racemase activity [GO:0018114]; aging [GO:0007568]; brain development [GO:0007420]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; response to organic cyclic compound [GO:0014070]	cysteine biosynthetic process from serine [GO:0006535]	aging [GO:0007568]; brain development [GO:0007420]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; D-serine ammonia-lyase activity [GO:0008721]; glycine binding [GO:0016594]; L-serine ammonia-lyase activity [GO:0003941]; magnesium ion binding [GO:0000287]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; serine racemase activity [GO:0030378]; threonine racemase activity [GO:0018114]
d2jc3g__d5iw8b___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; O-phosphoserine sulfhydrylase activity [GO:0033847]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; O-phosphoserine sulfhydrylase activity [GO:0033847]; pyridoxal phosphate binding [GO:0030170]
d2jc5a__d1de9a___1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; endonuclease activity [GO:0004519]; exodeoxyribonuclease III activity [GO:0008853]; metal ion binding [GO:0046872]; phosphodiesterase I activity [GO:0004528]; base-excision repair [GO:0006284]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	base-excision repair [GO:0006284]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]		cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; endonuclease activity [GO:0004519]; exodeoxyribonuclease III activity [GO:0008853]; metal ion binding [GO:0046872]; phosphodiesterase I activity [GO:0004528]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]
d2jcch1_d1l6za1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary membrane [GO:0060170]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lateral plasma membrane [GO:0016328]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; actin binding [GO:0003779]; bile acid transmembrane transporter activity [GO:0015125]; calmodulin binding [GO:0005516]; filamin binding [GO:0031005]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; Toll-like receptor binding [GO:0035325]; virus receptor activity [GO:0001618]; bile acid and bile salt transport [GO:0015721]; blood vessel development [GO:0001568]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; common myeloid progenitor cell proliferation [GO:0035726]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; insulin catabolic process [GO:1901143]; insulin receptor internalization [GO:0038016]; negative regulation of bone resorption [GO:0045779]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of vascular permeability [GO:0043116]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of vasculogenesis [GO:2001214]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell growth [GO:0001558]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell migration [GO:0010594]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of homophilic cell adhesion [GO:1903385]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of sprouting angiogenesis [GO:1903670]; wound healing, spreading of cells [GO:0044319]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	bile acid and bile salt transport [GO:0015721]; blood vessel development [GO:0001568]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; common myeloid progenitor cell proliferation [GO:0035726]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; insulin catabolic process [GO:1901143]; insulin receptor internalization [GO:0038016]; negative regulation of bone resorption [GO:0045779]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of vascular permeability [GO:0043116]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of vasculogenesis [GO:2001214]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell growth [GO:0001558]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell migration [GO:0010594]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of homophilic cell adhesion [GO:1903385]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of sprouting angiogenesis [GO:1903670]; wound healing, spreading of cells [GO:0044319]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell surface [GO:0009986]; ciliary membrane [GO:0060170]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lateral plasma membrane [GO:0016328]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; bile acid transmembrane transporter activity [GO:0015125]; calmodulin binding [GO:0005516]; filamin binding [GO:0031005]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; Toll-like receptor binding [GO:0035325]; virus receptor activity [GO:0001618]
d2jccm1_d2p1yg2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2jcfa__d3zlld___1				Proteobacteria		glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]				glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2jcja__d1mp5d___1	Metazoa		Chordata	Proteobacteria	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]		metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]
d2jcqa__d2iouc2__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	virus tail, fiber [GO:0098024]	epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]	
d2jcwa__d1jk9d1__1	Fungi	Fungi	Ascomycota	Ascomycota	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]
d2jd62__d3e1jk___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2jd62__d3qd8v1__1			Euryarchaeota	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2jd63__d2alxa___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2jd64__d3bvie1__1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d2jd65__d1iesb___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2jd66__d4evca___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2jd67__d5l8br1__1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]
d2jd68__d3qd8p1__1			Euryarchaeota	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2jd6b__d1f33e___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2jd6b__d4todr___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd6j__d1xved___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2jd6k__d3a68t___1		Viridiplantae	Euryarchaeota	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2jd6k__d4tobq___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd6l__d2pybb___1			Euryarchaeota	Spirochaetes	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]
d2jd6n__d5l8bq1__1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]
d2jd6q__d2htnh___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2jd6q__d5u1bf___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; efflux transmembrane transporter activity [GO:0015562]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]	efflux transmembrane transporter activity [GO:0015562]
d2jd6r__d5jkla___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2jd6s__d2vxia___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2jd6u__d4tocm___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd6w__d3hx2o___1			Euryarchaeota		cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]	
d2jd6x__d1ji4j___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2jd6y__d5lbhf___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2jd71__d1veqa___1			Euryarchaeota	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2jd74__d4p18t___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd78__d3re7h___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd79__d4p1cd___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	toluene catabolic process [GO:0042203]	cell [GO:0005623]		ferric iron binding [GO:0008199]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d2jd7a__d3isew___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd7b__d5c6fk1__1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d2jd7e__d1l8ib___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2jd7f__d3is8q___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd7g__d3re7n___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd7h__d5jkmf___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2jd7m__d1nf4j___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd7n__d4d8fd1__1			Euryarchaeota	Chlamydiae	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2jd7p__d3hx5h___1			Euryarchaeota		cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]	
d2jd7p__d5jkmg___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2jd7q__d3e1lj___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2jd7r__d2vxib___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2jd7t__d1oqbc___1		Viridiplantae	Euryarchaeota	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]	chloroplast [GO:0009507]	ferric iron binding [GO:0008199]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d2jd7u__d4toaf___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd7v__d2fg8b___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2jd7x__d4m1ic1__1			Euryarchaeota	Chlamydiae	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2jd7z__d1rcga___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]
d2jd81__d1mfru___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd82__d1rsva___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2jd82__d3oj5p___1			Euryarchaeota	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]
d2jd87__d1fzid___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2jd87__d5l8gh1__1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]
d2jd88__d4xktb___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2jd89__d5d8rk___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd8a__d4pg1a___1			Euryarchaeota	Cyanobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]	aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]
d2jd8c__d1dpse___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2jd8h__d3is8e___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd8j__d3hx2t___1			Euryarchaeota		cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]	
d2jd8k__d5l8bu1__1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]
d2jd8l__d4tohb___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd8n__d4m32a___1			Euryarchaeota	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2jd8n__d4tobw___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd8o__d1nf4i___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd8p__d4dast___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jd8p__d5jkkf___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2jd8s__d4xkte___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2jd8t__d1tkod___1			Euryarchaeota	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d2jd8u__d1ji4g___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2jd8w__d3hx5q___1			Euryarchaeota		cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]	
d2jd8y__d4p18r___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2jdic1_d5knde3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jdic2_d2qe7b1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jdic3_d5hkkd2__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jdid1_d4yxwc3__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jdka__d2vnva___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2jdlb__d1wuca___1	Viridiplantae		Streptophyta		rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]				rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	
d2jdma__d3dcqa___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	single-species biofilm formation [GO:0044010]	single-species biofilm formation [GO:0044010]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2jdmc__d3zdvd___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	single-species biofilm formation [GO:0044010]	single-species biofilm formation [GO:0044010]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2jdnc__d2vucc___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	single-species biofilm formation [GO:0044010]	single-species biofilm formation [GO:0044010]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2jdnd__d5mb1d___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2jdpb__d4aocc___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2jdqa__d2c1tb___1		Fungi	Negarnaviricota	Ascomycota	host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; virion [GO:0019012]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; 7-methylguanosine mRNA capping [GO:0006370]; cap snatching [GO:0075526]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host RNA polymerase II activity [GO:0039523]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; disordered domain specific binding [GO:0097718]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; NLS-bearing protein import into nucleus [GO:0006607]; proteasome localization [GO:0031144]; protein targeting to membrane [GO:0006612]	7-methylguanosine mRNA capping [GO:0006370]; cap snatching [GO:0075526]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host RNA polymerase II activity [GO:0039523]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	NLS-bearing protein import into nucleus [GO:0006607]; proteasome localization [GO:0031144]; protein targeting to membrane [GO:0006612]	host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; virion [GO:0019012]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]	disordered domain specific binding [GO:0097718]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]
d2jdub__d2jdpb___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	single-species biofilm formation [GO:0044010]	single-species biofilm formation [GO:0044010]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2jduc__d4ce8a___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	single-species biofilm formation [GO:0044010]	single-species biofilm formation [GO:0044010]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2jdya__d5a6ya___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2je6i1_d6aqga1__1			Crenarchaeota	Actinobacteria	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	lysyl-tRNA aminoacylation [GO:0006430]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasm [GO:0005737]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d2je8a5_d1f49e5__1			Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]	
d2je8a5_d3scra___1		Viridiplantae	Bacteroidetes	Streptophyta	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	beta-mannosidase activity [GO:0004567]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d2je8b3_d1jywc2__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2je8b3_d2vzoa4__1			Bacteroidetes	Actinobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]	beta-mannosidase activity [GO:0004567]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2je8b4_d5ihra5__1		Fungi	Bacteroidetes	Ascomycota	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]; beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]; carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]	beta-mannosidase activity [GO:0004567]	beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]
d2je8b5_d2depa___1			Bacteroidetes	Firmicutes	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	cellulase activity [GO:0008810]; endo-1,4-beta-xylanase activity [GO:0031176]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]			beta-mannosidase activity [GO:0004567]	cellulase activity [GO:0008810]; endo-1,4-beta-xylanase activity [GO:0031176]
d2je9d1_d1lob.4__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]					carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]
d2je9d1_d5dg2a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]					carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2jeab1_d2j65b1__1			Crenarchaeota	Aquificae	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]		poly(A) binding [GO:0008143]; RNA binding [GO:0003723]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d2jebb2_d2br2q2__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasmic exosome (RNase complex) [GO:0000177]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]	3'-5'-exoribonuclease activity [GO:0000175]
d2jeca1_d2w08e___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d2jecc1_d1ww6d___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]		apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d2jeia1_d2xgpa2__1		Fungi	Crenarchaeota	Ascomycota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d2jelh2_d2qr0e2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]; enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2jell2_d1tzha2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]; enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]
d2jema__d1oa2c___1		Fungi	Firmicutes	Ascomycota	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]	cellulase activity [GO:0008810]
d2jema__d5gm5f___1		Fungi	Firmicutes	Ascomycota	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	cellulase activity [GO:0008810]	cellulase activity [GO:0008810]
d2jena__d1qosa___1		Viridiplantae	Firmicutes	Streptophyta	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	polysaccharide catabolic process [GO:0000272]				cellulase activity [GO:0008810]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2jeua__d1tuej___1					host cell nucleus [GO:0042025]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]; host cytoskeleton [GO:0044163]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]	host cell nucleus [GO:0042025]; host cytoskeleton [GO:0044163]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]
d2jeva2_d4ufxa1__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; intracellular [GO:0005622]; diamine N-acetyltransferase activity [GO:0004145]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]; spermidine binding [GO:0019809]; angiogenesis [GO:0001525]; polyamine biosynthetic process [GO:0006596]; putrescine catabolic process [GO:0009447]; regulation of cell population proliferation [GO:0042127]; spermidine acetylation [GO:0032918]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]	angiogenesis [GO:0001525]; polyamine biosynthetic process [GO:0006596]; putrescine catabolic process [GO:0009447]; regulation of cell population proliferation [GO:0042127]; spermidine acetylation [GO:0032918]	N-terminal protein myristoylation [GO:0006499]	cytosol [GO:0005829]; intracellular [GO:0005622]		diamine N-acetyltransferase activity [GO:0004145]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]; spermidine binding [GO:0019809]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d2jexa__d2jeua___1					host cell nucleus [GO:0042025]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]	host cell nucleus [GO:0042025]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]
d2jf2a__d1j2za___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; identical protein binding [GO:0042802]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	lipid A biosynthetic process [GO:0009245]	lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; identical protein binding [GO:0042802]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]
d2jf2a__d2ic7b___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; identical protein binding [GO:0042802]; lipid A biosynthetic process [GO:0009245]	maltose O-acetyltransferase activity [GO:0008925]	lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; identical protein binding [GO:0042802]	maltose O-acetyltransferase activity [GO:0008925]
d2jf3a__d4husa___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; identical protein binding [GO:0042802]; lipid A biosynthetic process [GO:0009245]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	lipid A biosynthetic process [GO:0009245]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; identical protein binding [GO:0042802]	transferase activity, transferring acyl groups [GO:0016746]
d2jf6b__d1fhda___1	Viridiplantae		Streptophyta	Actinobacteria	strictosidine beta-glucosidase activity [GO:0050422]; alkaloid biosynthetic process [GO:0009821]; carbohydrate metabolic process [GO:0005975]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	alkaloid biosynthetic process [GO:0009821]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]			strictosidine beta-glucosidase activity [GO:0050422]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]
d2jfbd__d1xn1i___1				Proteobacteria		cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]		pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]		cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]		6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d2jfbk__d1xn1g___1				Proteobacteria		cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]		pathogenesis [GO:0009405]; riboflavin biosynthetic process [GO:0009231]		cytoplasm [GO:0005737]; riboflavin synthase complex [GO:0009349]		6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d2jfbl__d4j07a___1				Actinobacteria		riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]		riboflavin synthase complex [GO:0009349]		6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d2jfbn__d1hqka___1				Aquificae		cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]		cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]		6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d2jfcd2_d5u7nb___1			Proteobacteria	Deinococcus-Thermus	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	nitrogen compound metabolic process [GO:0006807]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2jfce1_d2tsac___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2jfce2_d1l9ob2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2jfcf1_d1mg3k___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	nitrogen compound metabolic process [GO:0006807]			periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2jfcf2_d3fyid2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	nitrogen compound metabolic process [GO:0006807]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2jfga1_d4hv4a1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]	ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]
d2jfta__d4ra2a1__1		Metazoa	Actinobacteria	Chordata	metal ion binding [GO:0046872]; protein serine/threonine phosphatase activity [GO:0004722]	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; calmodulin-dependent protein phosphatase activity [GO:0033192]; magnesium ion binding [GO:0000287]; magnesium-dependent protein serine/threonine phosphatase activity [GO:0004724]; manganese ion binding [GO:0030145]; protein serine/threonine phosphatase activity [GO:0004722]; R-SMAD binding [GO:0070412]; cell cycle arrest [GO:0007050]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dephosphorylation [GO:0016311]; N-terminal protein myristoylation [GO:0006499]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of transcription, DNA-templated [GO:0045893]; protein dephosphorylation [GO:0006470]		cell cycle arrest [GO:0007050]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dephosphorylation [GO:0016311]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; N-terminal protein myristoylation [GO:0006499]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of transcription, DNA-templated [GO:0045893]; protein dephosphorylation [GO:0006470]		cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; protein serine/threonine phosphatase activity [GO:0004722]	calmodulin-dependent protein phosphatase activity [GO:0033192]; magnesium-dependent protein serine/threonine phosphatase activity [GO:0004724]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; protein serine/threonine phosphatase activity [GO:0004722]; R-SMAD binding [GO:0070412]
d2jg3a1_d1sg9a___1			Deinococcus-Thermus	Thermotogae	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	nucleic acid binding [GO:0003676]; protein-(glutamine-N5) methyltransferase activity [GO:0102559]; protein-glutamine N-methyltransferase activity [GO:0036009]; peptidyl-glutamine methylation [GO:0018364]	DNA restriction-modification system [GO:0009307]	peptidyl-glutamine methylation [GO:0018364]			DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	nucleic acid binding [GO:0003676]; protein-(glutamine-N5) methyltransferase activity [GO:0102559]; protein-glutamine N-methyltransferase activity [GO:0036009]
d2jg3d2_d1yf2b2__1			Deinococcus-Thermus	Euryarchaeota	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	DNA binding [GO:0003677]
d2jg6a__d4ai5c___1			Firmicutes		DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]		base-excision repair [GO:0006284]				DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]	
d2jg7d__d4k57b___1	Metazoa		Chordata	Deinococcus-Thermus	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]					nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2jg7g__d1wndc___1	Metazoa		Chordata	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	cytosol [GO:0005829]; 1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; putrescine catabolic process [GO:0009447]		putrescine catabolic process [GO:0009447]		cytosol [GO:0005829]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]
d2jg7g__d4zxue1__1	Metazoa		Chordata	Firmicutes	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; glycine betaine biosynthetic process from choline [GO:0019285]		glycine betaine biosynthetic process from choline [GO:0019285]			nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2jg9a1_d2jg9e1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; postsynapse [GO:0098794]; synapse [GO:0045202]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; regulation of complement activation [GO:0030449]; synapse pruning [GO:0098883]	blood microparticle [GO:0072562]; cell [GO:0005623]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; postsynapse [GO:0098794]; synapse [GO:0045202]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; regulation of complement activation [GO:0030449]; synapse pruning [GO:0098883]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; regulation of complement activation [GO:0030449]; synapse pruning [GO:0098883]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; regulation of complement activation [GO:0030449]; synapse pruning [GO:0098883]	blood microparticle [GO:0072562]; cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; postsynapse [GO:0098794]; synapse [GO:0045202]	blood microparticle [GO:0072562]; cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; postsynapse [GO:0098794]; synapse [GO:0045202]		
d2jgaa__d4gibb___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; 5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; tRNA 2'-phosphotransferase activity [GO:0000215]; defense response to virus [GO:0051607]; nucleotide metabolic process [GO:0009117]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]	beta-phosphoglucomutase activity [GO:0008801]; hydrolase activity [GO:0016787]; magnesium ion binding [GO:0000287]; carbohydrate metabolic process [GO:0005975]	defense response to virus [GO:0051607]; nucleotide metabolic process [GO:0009117]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]		5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; tRNA 2'-phosphotransferase activity [GO:0000215]	beta-phosphoglucomutase activity [GO:0008801]; hydrolase activity [GO:0016787]; magnesium ion binding [GO:0000287]
d2jh2a1_d4uypa1__1			Firmicutes	Firmicutes	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	polysaccharide catabolic process [GO:0000272]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2jh2b__d2vo8a1__1			Firmicutes	Firmicutes	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate binding [GO:0030246]; exo-alpha-sialidase activity [GO:0004308]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; exo-alpha-sialidase activity [GO:0004308]; metal ion binding [GO:0046872]
d2jh2b__d5lxva___1			Firmicutes	Firmicutes	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate binding [GO:0030246]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	polysaccharide catabolic process [GO:0000272]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d2jhfa2_d1hsob2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; alcohol metabolic process [GO:0006066]; drug metabolic process [GO:0017144]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	alcohol metabolic process [GO:0006066]; drug metabolic process [GO:0017144]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d2jhif__d1lwub1__1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]; cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	fibrinogen complex [GO:0005577]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; platelet activation [GO:0030168]; protein polymerization [GO:0051258]	cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	platelet activation [GO:0030168]; protein polymerization [GO:0051258]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	fibrinogen complex [GO:0005577]	carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]	metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]
d2jhif__d2j3gb___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]; cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; recognition of apoptotic cell [GO:0043654]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	blood microparticle [GO:0072562]; collagen trimer [GO:0005581]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]	antigen binding [GO:0003823]; calcium-dependent protein binding [GO:0048306]; mannan binding [GO:2001065]; metal ion binding [GO:0046872]; proteoglycan binding [GO:0043394]
d2jhkf__d1rf1b1__1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]; cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2jhmf__d1fzae1__1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]; cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2jhsa__d1fsta___1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]
d2jhtb__d4utcb2__1	Metazoa		Chordata		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	protein dimerization activity [GO:0046983]
d2jhtd__d1ctna1__1	Metazoa		Chordata	Proteobacteria	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]		GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d2jhua2_d1wrfa___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	extracellular region [GO:0005576]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	extracellular region [GO:0005576]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	
d2jhva2_d5l2va___1	Metazoa		Chordata	Firmicutes	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	carbohydrate metabolic process [GO:0005975]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	extracellular region [GO:0005576]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2jhvb2_d2jkxa1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	extracellular region [GO:0005576]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]
d2jhvd2_d2jhwa___1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]
d2jhve2_d2d0ha1__1	Metazoa		Chordata	Firmicutes	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	carbohydrate metabolic process [GO:0005975]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	extracellular region [GO:0005576]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2jhvf2_d1l9na1__1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]
d2jhvf2_d2bxwb___1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]
d2jhwa__d1ug9a2__1	Metazoa		Chordata	Actinobacteria	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]; polysaccharide metabolic process [GO:0005976]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	polysaccharide metabolic process [GO:0005976]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]		GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; metal ion binding [GO:0046872]
d2jhxa__d1kmta1__1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]
d2jhxb__d1nudb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]; cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cell envelope organization [GO:0043163]; cellular protein modification process [GO:0006464]; hair follicle morphogenesis [GO:0031069]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein tetramerization [GO:0051262]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	calcium ion binding [GO:0005509]; catalytic activity [GO:0003824]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; transferase activity, transferring acyl groups [GO:0016746]
d2jhya__d2benb___1	Metazoa		Chordata	Proteobacteria	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]		negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]		GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	
d2ji1a1_d4c4bb___1			Proteobacteria	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d2ji1b1_d4c4uh___1			Proteobacteria	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d2ji1c1_d4bgla___1			Proteobacteria	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d2ji1d1_d4bffh___1			Proteobacteria	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d2ji1d1_d4bfjb___1			Proteobacteria	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d2ji2c1_d2hvbd___1			Proteobacteria	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d2ji3a1_d4bglb___1			Proteobacteria	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d2ji3a1_d4c4ud___1			Proteobacteria	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d2ji3d1_d4bffe___1			Proteobacteria	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	removal of superoxide radicals [GO:0019430]				iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d2ji6a1_d1mczo1__1			Proteobacteria	Proteobacteria	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	oxalate catabolic process [GO:0033611]	mandelate catabolic process [GO:0019596]			ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2ji6a1_d1pnqa1__1			Proteobacteria	Proteobacteria	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]	oxalate catabolic process [GO:0033611]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]
d2ji6a2_d1x7xb1__1		Metazoa	Proteobacteria	Chordata	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	oxalate catabolic process [GO:0033611]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]		mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]
d2ji6b2_d5hgxa2__1		Fungi	Proteobacteria	Ascomycota	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	oxalate catabolic process [GO:0033611]				ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d2ji7b1_d4fega2__1			Proteobacteria		ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]		oxalate catabolic process [GO:0033611]				ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	
d2ji7b3_d2ez9b2__1			Proteobacteria	Firmicutes	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	oxalate catabolic process [GO:0033611]				ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d2ji8b2_d1tkaa2__1		Fungi	Proteobacteria	Ascomycota	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	oxalate catabolic process [GO:0033611]	pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d2ji8b3_d1w85b1__1			Proteobacteria	Firmicutes	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	oxalate catabolic process [GO:0033611]	glycolytic process [GO:0006096]			ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2ji9a2_d3ea4a3__1		Viridiplantae	Proteobacteria	Streptophyta	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	oxalate catabolic process [GO:0033611]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2jibb3_d1ozga3__1			Proteobacteria	Proteobacteria	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; butanediol metabolic process [GO:0034077]	oxalate catabolic process [GO:0033611]	butanediol metabolic process [GO:0034077]			ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2jibb3_d4gm4a3__1			Proteobacteria	Proteobacteria	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	oxalate catabolic process [GO:0033611]	mandelate catabolic process [GO:0019596]			ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2jidb2_d5tnra___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	hydrolase activity [GO:0016787]
d2jifc2_d2reha1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid metabolic process [GO:0006631]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid metabolic process [GO:0006631]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d2jifd2_d1egdb1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid metabolic process [GO:0006631]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid metabolic process [GO:0006631]	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]
d2jima1_d1vleo1__1			Proteobacteria		periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]		Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]	
d2jioa1_d4kodk1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	periplasmic space [GO:0042597]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d2jipa1_d5ftkf1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	periplasmic space [GO:0042597]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d2jipa2_d1ti2e2__1			Proteobacteria		periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]		Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]	
d2jira1_d1vlfu1__1			Proteobacteria		periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]		Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]	
d2jira2_d1r27c2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	intrinsic component of membrane [GO:0031224]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; membrane [GO:0016020]; NarGHI complex [GO:0044799]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]; nitrate metabolic process [GO:0042126]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]; nitrate metabolic process [GO:0042126]	periplasmic space [GO:0042597]	intrinsic component of membrane [GO:0031224]; intrinsic component of the cytoplasmic side of the plasma membrane [GO:0031235]; membrane [GO:0016020]; NarGHI complex [GO:0044799]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]
d2jiwa1_d2wb5b3__1			Bacteroidetes	Firmicutes	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d2jiwa3_d1hp5a2__1			Bacteroidetes	Actinobacteria	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]	beta-N-acetylhexosaminidase activity [GO:0004563]
d2jiwb2_d3gxdb2__1		Metazoa	Bacteroidetes	Chordata	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d2jiwb3_d2j62a3__1			Bacteroidetes	Firmicutes	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d2jixd1_d3c5zc1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d2jixf1_d5cp7c1__1	Metazoa		Chordata									
d2jiza2_d2hldk2__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jiza2_d2zzzb___1	Metazoa		Chordata		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]		ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	
d2jizb1_d1kmha2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jizc1_d5kncd1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jizd3_d5cdfe3__1	Metazoa		Chordata	Proteobacteria	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jize2_d1n6la___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	actin cytoskeleton [GO:0015629]; anchored component of synaptic vesicle membrane [GO:0098993]; axon [GO:0030424]; axon terminus [GO:0043679]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic side of early endosome membrane [GO:0098559]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic early endosome [GO:0098842]; ruffle [GO:0001726]; somatodendritic compartment [GO:0036477]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; amyloid-beta clearance by transcytosis [GO:0150093]; blood coagulation [GO:0007596]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of exocytosis [GO:0045921]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286]; regulation of autophagosome assembly [GO:2000785]; regulation of endosome size [GO:0051036]; regulation of filopodium assembly [GO:0051489]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465]; viral RNA genome replication [GO:0039694]	ATP synthesis coupled proton transport [GO:0015986]	amyloid-beta clearance by transcytosis [GO:0150093]; blood coagulation [GO:0007596]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of exocytosis [GO:0045921]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286]; regulation of autophagosome assembly [GO:2000785]; regulation of endosome size [GO:0051036]; regulation of filopodium assembly [GO:0051489]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465]; viral RNA genome replication [GO:0039694]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	actin cytoskeleton [GO:0015629]; anchored component of synaptic vesicle membrane [GO:0098993]; axon [GO:0030424]; axon terminus [GO:0043679]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic side of early endosome membrane [GO:0098559]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic early endosome [GO:0098842]; ruffle [GO:0001726]; somatodendritic compartment [GO:0036477]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d2jize2_d2jj2i2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jize3_d3vr6f3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jizf1_d5ik2e1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jizh2_d4jvla___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; estrone sulfotransferase activity [GO:0004304]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid binding [GO:0005496]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; estrogen catabolic process [GO:0006711]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; positive regulation of fat cell differentiation [GO:0045600]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]	ATP synthesis coupled proton transport [GO:0015986]	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; estrogen catabolic process [GO:0006711]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; positive regulation of fat cell differentiation [GO:0045600]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	estrone sulfotransferase activity [GO:0004304]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid binding [GO:0005496]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]
d2jizj1_d3oeed1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jizj3_d3ssab3__1	Metazoa		Chordata	Euryarchaeota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jizk3_d2jj1a3__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jizm2_d1e79c3__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj1c2_d1knqa___1	Metazoa		Chordata	Proteobacteria	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; gluconokinase activity [GO:0046316]; D-gluconate catabolic process [GO:0046177]	ATP synthesis coupled proton transport [GO:0015986]	D-gluconate catabolic process [GO:0046177]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; gluconokinase activity [GO:0046316]
d2jj1c3_d2f43a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial envelope [GO:0005740]; mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP biosynthetic process [GO:0006754]; ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; cellular response to nitric oxide [GO:0071732]; oxidative phosphorylation [GO:0006119]	ATP synthesis coupled proton transport [GO:0015986]	ATP biosynthetic process [GO:0006754]; ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; cellular response to nitric oxide [GO:0071732]; oxidative phosphorylation [GO:0006119]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial envelope [GO:0005740]; mitochondrial inner membrane [GO:0005743]; mitochondrial proton-transporting ATP synthase complex [GO:0005753]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj1c3_d3ziae3__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj1d1_d2jizh1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj1e3_d3gqbb3__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj1i2_d1uaaa1__1	Metazoa		Chordata	Proteobacteria	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cytosol [GO:0005829]; 3'-5' exonuclease activity [GO:0008408]; ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; single-stranded DNA binding [GO:0003697]; bacterial-type DNA replication [GO:0044787]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; recombinational repair [GO:0000725]; response to radiation [GO:0009314]	ATP synthesis coupled proton transport [GO:0015986]	bacterial-type DNA replication [GO:0044787]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; recombinational repair [GO:0000725]; response to radiation [GO:0009314]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	cytosol [GO:0005829]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	3'-5' exonuclease activity [GO:0008408]; ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; single-stranded DNA binding [GO:0003697]
d2jj1j1_d1w0ke2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj1j3_d2jj2d3__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj1l3_d5hkkb3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj1m1_d2jj1i1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj1m3_d1efra1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj1m3_d5hkkf3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj2a1_d2hlds1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj2a2_d2c95b1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]	ATP synthesis coupled proton transport [GO:0015986]	ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d2jj2c3_d1w0ka1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj2c3_d5hkkm3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj2d2_d1tf7c1__1	Metazoa		Chordata	Cyanobacteria	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	ATP synthesis coupled proton transport [GO:0015986]	circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]
d2jj2h1_d1w0kf2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj2i1_d1skyb2__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj2j1_d3ziap1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj2j2_d2xokf2__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj2j3_d3a5ce3__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj2l1_d1skyb2__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj2l3_d5kndd3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2jj6a__d1z78a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; intracellular [GO:0005622]; carbohydrate binding [GO:0030246]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]; activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]		activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]	cytoplasm [GO:0005737]; intracellular [GO:0005622]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]	carbohydrate binding [GO:0030246]	calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]
d2jj6a__d2aend___1	Metazoa		Chordata		cytoplasm [GO:0005737]; intracellular [GO:0005622]; carbohydrate binding [GO:0030246]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]		permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; intracellular [GO:0005622]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	carbohydrate binding [GO:0030246]	
d2jjvb__d2gsgc___1	Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d2jjvb__d4x7cd1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d2jk5b2_d3lzfl1__1			Actinobacteria	Negarnaviricota	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	voltage-gated potassium channel complex [GO:0008076]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	host cell surface receptor binding [GO:0046789]
d2jkha__d3s0na___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptide binding [GO:0042277]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; angiotensin maturation [GO:0002003]; basement membrane disassembly [GO:0034769]; cellular response to glucose stimulus [GO:0071333]; extracellular matrix disassembly [GO:0022617]; interleukin-1 beta biosynthetic process [GO:0050720]; midbrain development [GO:0030901]; positive regulation of angiogenesis [GO:0045766]; regulation of inflammatory response [GO:0050727]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	angiotensin maturation [GO:0002003]; basement membrane disassembly [GO:0034769]; cellular response to glucose stimulus [GO:0071333]; extracellular matrix disassembly [GO:0022617]; interleukin-1 beta biosynthetic process [GO:0050720]; midbrain development [GO:0030901]; positive regulation of angiogenesis [GO:0045766]; regulation of inflammatory response [GO:0050727]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	peptide binding [GO:0042277]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2jkja1_d1ut2h___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]	pilus [GO:0009289]			pilus [GO:0009289]	pilus [GO:0009289]		
d2jkja1_d4xo8b___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d2jkjd1_d4xoba2__1			Proteobacteria	Proteobacteria	pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d2jklb1_d4z3gb1__1			Proteobacteria	Proteobacteria	pilus [GO:0009289]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]		cell adhesion [GO:0007155]	pilus [GO:0009289]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2jknb1_d4av5d___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d2jknd1_d1ut2d___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]	pilus [GO:0009289]			pilus [GO:0009289]	pilus [GO:0009289]		
d2jknd1_d4z3jb___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]		cell adhesion [GO:0007155]	pilus [GO:0009289]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2jknf1_d1r17a1__1			Proteobacteria	Firmicutes	pilus [GO:0009289]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	pilus [GO:0009289]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]		metal ion binding [GO:0046872]
d2jkri__d1ioua___1	Metazoa	Fungi	Chordata	Ascomycota	AP-2 adaptor complex [GO:0030122]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; terminal bouton [GO:0043195]; disordered domain specific binding [GO:0097718]; lipid binding [GO:0008289]; low-density lipoprotein particle receptor binding [GO:0050750]; signal sequence binding [GO:0005048]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; protein-containing complex assembly [GO:0065003]; synaptic vesicle endocytosis [GO:0048488]	cytosol [GO:0005829]; endosome [GO:0005768]; fungal-type vacuole [GO:0000324]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; SNARE complex [GO:0031201]; palmitoyltransferase activity [GO:0016409]; SNAP receptor activity [GO:0005484]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; vacuole fusion, non-autophagic [GO:0042144]; vesicle fusion [GO:0006906]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; protein-containing complex assembly [GO:0065003]; synaptic vesicle endocytosis [GO:0048488]	endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; vacuole fusion, non-autophagic [GO:0042144]; vesicle fusion [GO:0006906]	AP-2 adaptor complex [GO:0030122]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; terminal bouton [GO:0043195]	cytosol [GO:0005829]; endosome [GO:0005768]; fungal-type vacuole [GO:0000324]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; SNARE complex [GO:0031201]	disordered domain specific binding [GO:0097718]; lipid binding [GO:0008289]; low-density lipoprotein particle receptor binding [GO:0050750]; signal sequence binding [GO:0005048]	palmitoyltransferase activity [GO:0016409]; SNAP receptor activity [GO:0005484]
d2jkvb2_d4fgwa2__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate catabolic process [GO:0046177]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	cell [GO:0005623]; cytosol [GO:0005829]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; intracellular accumulation of glycerol [GO:0006973]; NADH oxidation [GO:0006116]; protein import into peroxisome matrix [GO:0016558]	D-gluconate catabolic process [GO:0046177]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; intracellular accumulation of glycerol [GO:0006973]; NADH oxidation [GO:0006116]; protein import into peroxisome matrix [GO:0016558]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]	glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]
d2jkve1_d5nqqb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate catabolic process [GO:0046177]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	D-gluconate catabolic process [GO:0046177]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]	L-lactate dehydrogenase activity [GO:0004459]
d2jkwb__d1shwa___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]		angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]	periplasmic space [GO:0042597]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2jkxa1_d1vfka4__1	Fungi		Ascomycota		extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]				extracellular region [GO:0005576]		galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	
d2jkxa2_d1w8oa2__1	Fungi		Ascomycota	Actinobacteria	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]		metabolic process [GO:0008152]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d2jl0a1_d4akqa2__1				Firmicutes		outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2jl3a2_d1adwa___1				Proteobacteria		periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2jl4a2_d14gsb1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; maleylpyruvate isomerase activity [GO:0050077]; aromatic amino acid family metabolic process [GO:0009072]; aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	aromatic amino acid family metabolic process [GO:0009072]; aromatic compound catabolic process [GO:0019439]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	maleylpyruvate isomerase activity [GO:0050077]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2jl4a2_d2on5h2__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cytoplasm [GO:0005737]; maleylpyruvate isomerase activity [GO:0050077]; aromatic amino acid family metabolic process [GO:0009072]; aromatic compound catabolic process [GO:0019439]	transferase activity [GO:0016740]	aromatic amino acid family metabolic process [GO:0009072]; aromatic compound catabolic process [GO:0019439]		cytoplasm [GO:0005737]		maleylpyruvate isomerase activity [GO:0050077]	transferase activity [GO:0016740]
d2jlja__d3c03a___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; pathogenesis [GO:0009405]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]; protein secretion [GO:0009306]	pathogenesis [GO:0009405]; protein secretion [GO:0009306]	protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]		dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]
d2jlja__d3t7ya___1			Proteobacteria	Chlamydiae	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; pathogenesis [GO:0009405]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein secretion [GO:0009306]	pathogenesis [GO:0009405]; protein secretion [GO:0009306]	protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		
d2jlmd__d5g22a2__1			Proteobacteria	Apicomplexa	N-acetyltransferase activity [GO:0008080]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]		N-terminal protein myristoylation [GO:0006499]			N-acetyltransferase activity [GO:0008080]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d2jlsa1_d4urzr1__1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d2jlvb1_d5e4fa2__1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2jlya1_d3kqud2__1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2jmua1_d3n0ya___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; thiamin-triphosphatase activity [GO:0050333]; dephosphorylation [GO:0016311]; thiamine diphosphate metabolic process [GO:0042357]; thiamine metabolic process [GO:0006772]	adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	dephosphorylation [GO:0016311]; thiamine diphosphate metabolic process [GO:0042357]; thiamine metabolic process [GO:0006772]		cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; thiamin-triphosphatase activity [GO:0050333]	adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2jn3a__d1bbpa___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	extracellular region [GO:0005576]; pigment binding [GO:0031409]; protein-chromophore linkage [GO:0018298]		protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	lipid binding [GO:0008289]	pigment binding [GO:0031409]
d2jnaa1_d2noca1__1			Proteobacteria	Proteobacteria								
d2jnba1_d1w42a1__1	Metazoa		Chordata	Euryarchaeota	box C/D snoRNP complex [GO:0031428]; dense fibrillar component [GO:0001651]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; small-subunit processome [GO:0032040]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4atac snRNP [GO:0005690]; ATPase binding [GO:0051117]; box C/D snoRNA binding [GO:0034512]; RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511]; U4 snRNA binding [GO:0030621]; U4atac snRNA binding [GO:0030622]; box C/D snoRNP assembly [GO:0000492]; maturation of LSU-rRNA [GO:0000470]; mRNA splicing, via spliceosome [GO:0000398]; rRNA processing [GO:0006364]; single fertilization [GO:0007338]	cytosolic large ribosomal subunit [GO:0022625]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	box C/D snoRNP assembly [GO:0000492]; maturation of LSU-rRNA [GO:0000470]; mRNA splicing, via spliceosome [GO:0000398]; rRNA processing [GO:0006364]; single fertilization [GO:0007338]	translation [GO:0006412]	box C/D snoRNP complex [GO:0031428]; dense fibrillar component [GO:0001651]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; small-subunit processome [GO:0032040]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4atac snRNP [GO:0005690]	cytosolic large ribosomal subunit [GO:0022625]	ATPase binding [GO:0051117]; box C/D snoRNA binding [GO:0034512]; RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511]; U4atac snRNA binding [GO:0030622]; U4 snRNA binding [GO:0030621]	RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]
d2jnfa__d1scmb___1	Metazoa	Metazoa	Arthropoda	Mollusca	calcium ion binding [GO:0005509]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]				myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	calcium ion binding [GO:0005509]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]
d2jnfa__d2ehba___1	Metazoa	Viridiplantae	Arthropoda	Streptophyta	calcium ion binding [GO:0005509]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plant-type vacuole membrane [GO:0009705]; ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; response to salt stress [GO:0009651]		intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]; nucleus [GO:0005634]; plant-type vacuole membrane [GO:0009705]	calcium ion binding [GO:0005509]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d2jnpa__d3lika1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d2joqa1_d1rwua___1			Proteobacteria	Proteobacteria		cytosol [GO:0005829]				cytosol [GO:0005829]		
d2joqa1_d2h9za1__1			Proteobacteria	Proteobacteria								
d2joza1_d2at7x___1			Firmicutes									
d2joza1_d5ur9g1__1		Metazoa	Firmicutes	Chordata		azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]; epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]		epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]		azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]		fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]
d2jpra__d4ph2b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	viral nucleocapsid [GO:0019013]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2jptb__d3n22a___1	Metazoa		Chordata		nucleus [GO:0005634]; sarcoplasmic reticulum [GO:0016529]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; regulation of heart contraction [GO:0008016]		positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; regulation of heart contraction [GO:0008016]		nucleus [GO:0005634]; sarcoplasmic reticulum [GO:0016529]		ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]	
d2jq4a1_d2kora___1			Proteobacteria	Actinobacteria		cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]				cytoplasm [GO:0005737]		acyl carrier activity [GO:0000036]
d2jqha__d5fvka___1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; late endosome membrane [GO:0031902]; nucleus [GO:0005634]; spindle pole [GO:0000922]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cholesterol transport [GO:0030301]; endosomal transport [GO:0016197]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ESCRT III complex disassembly [GO:1904903]; late endosomal microautophagy [GO:0061738]; macroautophagy [GO:0016236]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; negative regulation of cell death [GO:0060548]; negative regulation of exosomal secretion [GO:1903542]; nucleus organization [GO:0006997]; positive regulation of centriole elongation [GO:1903724]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of viral life cycle [GO:1903902]; positive regulation of viral process [GO:0048524]; positive regulation of viral release from host cell [GO:1902188]; potassium ion transport [GO:0006813]; protein depolymerization [GO:0051261]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; regulation of viral process [GO:0050792]; response to lipid [GO:0033993]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; vacuole organization [GO:0007033]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]	cell [GO:0005623]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; ESCRT IV complex [GO:1990621]; membrane [GO:0016020]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; intralumenal vesicle formation [GO:0070676]; late endosome to vacuole transport [GO:0045324]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein transport [GO:0015031]; sterol metabolic process [GO:0016125]; vacuole organization [GO:0007033]	cholesterol transport [GO:0030301]; endosomal transport [GO:0016197]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ESCRT III complex disassembly [GO:1904903]; late endosomal microautophagy [GO:0061738]; macroautophagy [GO:0016236]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; negative regulation of cell death [GO:0060548]; negative regulation of exosomal secretion [GO:1903542]; nucleus organization [GO:0006997]; positive regulation of centriole elongation [GO:1903724]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of viral life cycle [GO:1903902]; positive regulation of viral process [GO:0048524]; positive regulation of viral release from host cell [GO:1902188]; potassium ion transport [GO:0006813]; protein depolymerization [GO:0051261]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; regulation of viral process [GO:0050792]; response to lipid [GO:0033993]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; vacuole organization [GO:0007033]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]	intralumenal vesicle formation [GO:0070676]; late endosome to vacuole transport [GO:0045324]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein transport [GO:0015031]; sterol metabolic process [GO:0016125]; vacuole organization [GO:0007033]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; late endosome membrane [GO:0031902]; nucleus [GO:0005634]; spindle pole [GO:0000922]	cell [GO:0005623]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; ESCRT IV complex [GO:1990621]; membrane [GO:0016020]; nucleus [GO:0005634]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2jqia__d1k2na___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]
d2jrha1_d2kfja1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; activation of protein kinase activity [GO:0032147]; blood vessel development [GO:0001568]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; negative regulation of cellular senescence [GO:2000773]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of p38MAPK cascade [GO:1900745]; protein autophosphorylation [GO:0046777]; signal transduction by protein phosphorylation [GO:0023014]	Cdc24p-Far1p-Gbetagamma complex [GO:0120171]; cell division site [GO:0032153]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; division septum [GO:0000935]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]; nucleus [GO:0005634]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; cellular bud site selection [GO:0000282]; chemotropism [GO:0043577]; protein localization to cell cortex [GO:0072697]; regulation of exit from mitosis [GO:0007096]; regulation of Rho protein signal transduction [GO:0035023]; septin ring organization [GO:0031106]; small GTPase mediated signal transduction [GO:0007264]	activation of protein kinase activity [GO:0032147]; blood vessel development [GO:0001568]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; negative regulation of cellular senescence [GO:2000773]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of p38MAPK cascade [GO:1900745]; protein autophosphorylation [GO:0046777]; signal transduction by protein phosphorylation [GO:0023014]	cellular bud site selection [GO:0000282]; chemotropism [GO:0043577]; protein localization to cell cortex [GO:0072697]; regulation of exit from mitosis [GO:0007096]; regulation of Rho protein signal transduction [GO:0035023]; septin ring organization [GO:0031106]; small GTPase mediated signal transduction [GO:0007264]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	Cdc24p-Far1p-Gbetagamma complex [GO:0120171]; cell division site [GO:0032153]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; division septum [GO:0000935]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]; nucleus [GO:0005634]	ATP binding [GO:0005524]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	Rho guanyl-nucleotide exchange factor activity [GO:0005089]
d2jrlb__d1ys6b2__1			Aquificae	Actinobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; calcium ion binding [GO:0005509]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; magnesium ion binding [GO:0000287]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; growth involved in symbiotic interaction [GO:0044110]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	growth involved in symbiotic interaction [GO:0044110]		cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	calcium ion binding [GO:0005509]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; magnesium ion binding [GO:0000287]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2jsca__d3r6sf2__1			Actinobacteria	Actinobacteria	cadmium ion binding [GO:0046870]; cadmium ion sensor activity [GO:0097063]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; lead ion binding [GO:0032791]; regulation of gene expression [GO:0010468]; response to cadmium ion [GO:0046686]; response to lead ion [GO:0010288]	protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	regulation of gene expression [GO:0010468]; response to cadmium ion [GO:0046686]; response to lead ion [GO:0010288]	regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]		protein-DNA complex [GO:0032993]	cadmium ion binding [GO:0046870]; cadmium ion sensor activity [GO:0097063]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; lead ion binding [GO:0032791]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2jssa2_d2nqbc___1	Fungi	Metazoa	Ascomycota	Arthropoda	nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleosome [GO:0000786]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromatin silencing at silent mating-type cassette [GO:0030466]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; regulation of transcription by RNA polymerase II [GO:0006357]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromatin silencing at silent mating-type cassette [GO:0030466]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; regulation of transcription by RNA polymerase II [GO:0006357]	chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleosome [GO:0000786]; nucleus [GO:0005634]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]	chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2jsya__d5enub___1			Firmicutes	Proteobacteria	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	thioredoxin peroxidase activity [GO:0008379]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]
d2jsza__d1guld2__1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]	thioredoxin peroxidase activity [GO:0008379]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2jt3a__d2e30a___1	Metazoa	Metazoa	Chordata	Chordata	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cation-transporting ATPase complex [GO:0090533]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; T-tubule [GO:0030315]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; molecular adaptor activity [GO:0060090]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; potassium:proton antiporter activity [GO:0015386]; protein binding, bridging [GO:0030674]; protein phosphatase 2B binding [GO:0030346]; sodium:proton antiporter activity [GO:0015385]; sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential [GO:0086040]; solute:proton antiporter activity [GO:0015299]; cardiac muscle cell contraction [GO:0086003]; cardiac muscle cell differentiation [GO:0055007]; cell migration [GO:0016477]; cellular response to acidic pH [GO:0071468]; cellular response to antibiotic [GO:0071236]; cellular response to cold [GO:0070417]; cellular response to electrical stimulus [GO:0071257]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular sodium ion homeostasis [GO:0006883]; hyaluronan catabolic process [GO:0030214]; ion transport [GO:0006811]; maintenance of cell polarity [GO:0030011]; negative regulation of apoptotic process [GO:0043066]; neuron death [GO:0070997]; positive regulation of action potential [GO:0045760]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of calcium:sodium antiporter activity [GO:1903281]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell growth [GO:0030307]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of the force of heart contraction [GO:0098735]; positive regulation of transcription by RNA polymerase II [GO:0045944]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; proton transmembrane transport [GO:1902600]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of focal adhesion assembly [GO:0051893]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; regulation of sensory perception of pain [GO:0051930]; regulation of stress fiber assembly [GO:0051492]; regulation of the force of heart contraction by cardiac conduction [GO:0086092]; response to acidic pH [GO:0010447]; response to muscle stretch [GO:0035994]; sodium ion export across plasma membrane [GO:0036376]; sodium ion import across plasma membrane [GO:0098719]	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cardiac muscle cell contraction [GO:0086003]; cardiac muscle cell differentiation [GO:0055007]; cell migration [GO:0016477]; cellular response to acidic pH [GO:0071468]; cellular response to antibiotic [GO:0071236]; cellular response to cold [GO:0070417]; cellular response to electrical stimulus [GO:0071257]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular sodium ion homeostasis [GO:0006883]; hyaluronan catabolic process [GO:0030214]; ion transport [GO:0006811]; maintenance of cell polarity [GO:0030011]; negative regulation of apoptotic process [GO:0043066]; neuron death [GO:0070997]; positive regulation of action potential [GO:0045760]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of calcium:sodium antiporter activity [GO:1903281]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell growth [GO:0030307]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of the force of heart contraction [GO:0098735]; positive regulation of transcription by RNA polymerase II [GO:0045944]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; proton transmembrane transport [GO:1902600]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of focal adhesion assembly [GO:0051893]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; regulation of sensory perception of pain [GO:0051930]; regulation of stress fiber assembly [GO:0051492]; regulation of the force of heart contraction by cardiac conduction [GO:0086092]; response to acidic pH [GO:0010447]; response to muscle stretch [GO:0035994]; sodium ion export across plasma membrane [GO:0036376]; sodium ion import across plasma membrane [GO:0098719]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cation-transporting ATPase complex [GO:0090533]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; T-tubule [GO:0030315]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]	calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; molecular adaptor activity [GO:0060090]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; potassium:proton antiporter activity [GO:0015386]; protein binding, bridging [GO:0030674]; protein phosphatase 2B binding [GO:0030346]; sodium:proton antiporter activity [GO:0015385]; sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential [GO:0086040]; solute:proton antiporter activity [GO:0015299]
d2jt4b__d3ehvc___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP-dependent protein binding [GO:0043008]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; ascospore formation [GO:0030437]; modification-dependent protein catabolic process [GO:0019941]; protein deubiquitination [GO:0016579]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	ascospore formation [GO:0030437]; modification-dependent protein catabolic process [GO:0019941]; protein deubiquitination [GO:0016579]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ATP-dependent protein binding [GO:0043008]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2jt6a__d3dpfa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d2jtta__d1irjg___1	Metazoa	Metazoa	Chordata	Chordata	beta-catenin destruction complex [GO:0030877]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; aging [GO:0007568]; cardiac muscle cell differentiation [GO:0055007]; cellular response to calcium ion [GO:0071277]; cellular response to leukemia inhibitory factor [GO:1990830]; heart development [GO:0007507]; negative regulation of cell death [GO:0060548]; positive regulation of DNA replication [GO:0045740]; response to growth hormone [GO:0060416]	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	aging [GO:0007568]; cardiac muscle cell differentiation [GO:0055007]; cellular response to calcium ion [GO:0071277]; cellular response to leukemia inhibitory factor [GO:1990830]; heart development [GO:0007507]; negative regulation of cell death [GO:0060548]; positive regulation of DNA replication [GO:0045740]; response to growth hormone [GO:0060416]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	beta-catenin destruction complex [GO:0030877]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]	antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d2jtta__d3ewva___1	Metazoa	Metazoa	Chordata	Chordata	beta-catenin destruction complex [GO:0030877]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; aging [GO:0007568]; cardiac muscle cell differentiation [GO:0055007]; cellular response to calcium ion [GO:0071277]; cellular response to leukemia inhibitory factor [GO:1990830]; heart development [GO:0007507]; negative regulation of cell death [GO:0060548]; positive regulation of DNA replication [GO:0045740]; response to growth hormone [GO:0060416]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	aging [GO:0007568]; cardiac muscle cell differentiation [GO:0055007]; cellular response to calcium ion [GO:0071277]; cellular response to leukemia inhibitory factor [GO:1990830]; heart development [GO:0007507]; negative regulation of cell death [GO:0060548]; positive regulation of DNA replication [GO:0045740]; response to growth hormone [GO:0060416]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	beta-catenin destruction complex [GO:0030877]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d2jttb__d1ncya___1	Metazoa	Metazoa	Chordata	Chordata	beta-catenin destruction complex [GO:0030877]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; aging [GO:0007568]; cardiac muscle cell differentiation [GO:0055007]; cellular response to calcium ion [GO:0071277]; cellular response to leukemia inhibitory factor [GO:1990830]; heart development [GO:0007507]; negative regulation of cell death [GO:0060548]; positive regulation of DNA replication [GO:0045740]; response to growth hormone [GO:0060416]	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	aging [GO:0007568]; cardiac muscle cell differentiation [GO:0055007]; cellular response to calcium ion [GO:0071277]; cellular response to leukemia inhibitory factor [GO:1990830]; heart development [GO:0007507]; negative regulation of cell death [GO:0060548]; positive regulation of DNA replication [GO:0045740]; response to growth hormone [GO:0060416]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	beta-catenin destruction complex [GO:0030877]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear envelope lumen [GO:0005641]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	troponin complex [GO:0005861]	protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]
d2ju3a__d4alba___1	Metazoa		Chordata	Firmicutes	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; lysophospholipid:sodium symporter activity [GO:0051978]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]	carboxy-lyase activity [GO:0016831]; aromatic compound catabolic process [GO:0019439]; response to toxic substance [GO:0009636]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]	aromatic compound catabolic process [GO:0019439]; response to toxic substance [GO:0009636]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]		antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; lysophospholipid:sodium symporter activity [GO:0051978]; phospholipid binding [GO:0005543]	carboxy-lyase activity [GO:0016831]
d2ju3a__d5u6gb___1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; lysophospholipid:sodium symporter activity [GO:0051978]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; lysophospholipid:sodium symporter activity [GO:0051978]; phospholipid binding [GO:0005543]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d2jula__d5b8ib___1	Metazoa	Fungi	Chordata	Ascomycota	axon [GO:0030424]; axon terminus [GO:0043679]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; voltage-gated potassium channel complex [GO:0008076]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; core promoter sequence-specific DNA binding [GO:0001046]; DNA binding [GO:0003677]; ion channel binding [GO:0044325]; magnesium ion binding [GO:0000287]; potassium channel activity [GO:0005267]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; sequence-specific DNA binding [GO:0043565]; voltage-gated ion channel activity [GO:0005244]; apoptotic process [GO:0006915]; behavioral response to pain [GO:0048266]; intracellular protein transport [GO:0006886]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; potassium ion transport [GO:0006813]; protein localization to plasma membrane [GO:0072659]; regulation of neuron apoptotic process [GO:0043523]; regulation of potassium ion transmembrane transport [GO:1901379]; response to pain [GO:0048265]; sensory perception of pain [GO:0019233]	phosphoprotein phosphatase activity [GO:0004721]	apoptotic process [GO:0006915]; behavioral response to pain [GO:0048266]; intracellular protein transport [GO:0006886]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; potassium ion transport [GO:0006813]; protein localization to plasma membrane [GO:0072659]; regulation of neuron apoptotic process [GO:0043523]; regulation of potassium ion transmembrane transport [GO:1901379]; response to pain [GO:0048265]; sensory perception of pain [GO:0019233]		axon [GO:0030424]; axon terminus [GO:0043679]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; voltage-gated potassium channel complex [GO:0008076]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; core promoter sequence-specific DNA binding [GO:0001046]; DNA binding [GO:0003677]; ion channel binding [GO:0044325]; magnesium ion binding [GO:0000287]; potassium channel activity [GO:0005267]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; sequence-specific DNA binding [GO:0043565]; voltage-gated ion channel activity [GO:0005244]	phosphoprotein phosphatase activity [GO:0004721]
d2jv9a1_d1sh5a2__1	Metazoa	Metazoa	Chordata	Chordata	contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; I band [GO:0031674]; M band [GO:0031430]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; calmodulin binding [GO:0005516]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin phosphatase regulator activity [GO:0017020]; protein phosphatase 1 binding [GO:0008157]; protein phosphatase inhibitor activity [GO:0004864]; protein self-association [GO:0043621]; tropomyosin binding [GO:0005523]; actin cytoskeleton organization [GO:0030036]; muscle organ morphogenesis [GO:0048644]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to drug [GO:0042493]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; protein N-terminus binding [GO:0047485]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; response to nutrient [GO:0007584]; wound healing [GO:0042060]	actin cytoskeleton organization [GO:0030036]; muscle organ morphogenesis [GO:0048644]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to drug [GO:0042493]	hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; response to nutrient [GO:0007584]; wound healing [GO:0042060]	contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; I band [GO:0031674]; M band [GO:0031430]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; brush border [GO:0005903]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	calmodulin binding [GO:0005516]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin phosphatase regulator activity [GO:0017020]; protein phosphatase 1 binding [GO:0008157]; protein phosphatase inhibitor activity [GO:0004864]; protein self-association [GO:0043621]; tropomyosin binding [GO:0005523]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; protein N-terminus binding [GO:0047485]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]
d2jv9a1_d2d86a1__1	Metazoa	Metazoa	Chordata	Chordata	contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; I band [GO:0031674]; M band [GO:0031430]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; calmodulin binding [GO:0005516]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin phosphatase regulator activity [GO:0017020]; protein phosphatase 1 binding [GO:0008157]; protein phosphatase inhibitor activity [GO:0004864]; protein self-association [GO:0043621]; tropomyosin binding [GO:0005523]; actin cytoskeleton organization [GO:0030036]; muscle organ morphogenesis [GO:0048644]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to drug [GO:0042493]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; epidermal growth factor receptor binding [GO:0005154]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; Rac guanyl-nucleotide exchange factor activity [GO:0030676]; SH3/SH2 adaptor activity [GO:0005070]; angiogenesis [GO:0001525]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; lamellipodium assembly [GO:0030032]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell adhesion [GO:0045785]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; response to drug [GO:0042493]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vesicle fusion [GO:0006906]	actin cytoskeleton organization [GO:0030036]; muscle organ morphogenesis [GO:0048644]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to drug [GO:0042493]	angiogenesis [GO:0001525]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; lamellipodium assembly [GO:0030032]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell adhesion [GO:0045785]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; response to drug [GO:0042493]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vesicle fusion [GO:0006906]	contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; I band [GO:0031674]; M band [GO:0031430]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	calmodulin binding [GO:0005516]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin phosphatase regulator activity [GO:0017020]; protein phosphatase 1 binding [GO:0008157]; protein phosphatase inhibitor activity [GO:0004864]; protein self-association [GO:0043621]; tropomyosin binding [GO:0005523]	epidermal growth factor receptor binding [GO:0005154]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; Rac guanyl-nucleotide exchange factor activity [GO:0030676]; SH3/SH2 adaptor activity [GO:0005070]
d2jvba__d5antc___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; Dcp1-Dcp2 complex [GO:0098745]; nucleus [GO:0005634]; P-body [GO:0000932]; chromatin binding [GO:0003682]; hydrolase activity [GO:0016787]; m7G(5')pppN diphosphatase activity [GO:0050072]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; mRNA processing [GO:0006397]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; stress granule assembly [GO:0034063]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTP diphosphatase activity [GO:0036219]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]; aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; mRNA processing [GO:0006397]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; stress granule assembly [GO:0034063]	aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; Dcp1-Dcp2 complex [GO:0098745]; nucleus [GO:0005634]; P-body [GO:0000932]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	chromatin binding [GO:0003682]; hydrolase activity [GO:0016787]; m7G(5')pppN diphosphatase activity [GO:0050072]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTPase activity [GO:0003924]; GTP diphosphatase activity [GO:0036219]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]
d2jvia1_d3lter___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]		kinase activity [GO:0016301]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d2jvja1_d3cz5b___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]		kinase activity [GO:0016301]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d2jvka1_d1ab5a___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	kinase activity [GO:0016301]; metal ion binding [GO:0046872]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d2jw2a2_d2gyta1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; lipid droplet [GO:0005811]; mitochondrial membrane [GO:0031966]; GTPase activator activity [GO:0005096]; lipid binding [GO:0008289]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	caveola [GO:0005901]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; GTPase activator activity [GO:0005096]; lipid binding [GO:0008289]; SH2 domain binding [GO:0042169]; actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	actin cytoskeleton organization [GO:0030036]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; heart morphogenesis [GO:0003007]; hindbrain morphogenesis [GO:0021575]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; neural tube closure [GO:0001843]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; mitochondrial membrane [GO:0031966]	caveola [GO:0005901]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]	GTPase activator activity [GO:0005096]; lipid binding [GO:0008289]	GTPase activator activity [GO:0005096]; lipid binding [GO:0008289]; SH2 domain binding [GO:0042169]
d2jw8a__d2ca1a1__1					host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; host cell perinuclear region of cytoplasm [GO:0044220]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; viral nucleocapsid [GO:0019013]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]			host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; host cell perinuclear region of cytoplasm [GO:0044220]; viral nucleocapsid [GO:0019013]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; viral nucleocapsid [GO:0019013]	RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d2jw8b__d2cjrd___1					host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; host cell perinuclear region of cytoplasm [GO:0044220]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; host cell perinuclear region of cytoplasm [GO:0044220]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]			host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; host cell perinuclear region of cytoplasm [GO:0044220]; viral nucleocapsid [GO:0019013]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell Golgi apparatus [GO:0044177]; host cell perinuclear region of cytoplasm [GO:0044220]; viral nucleocapsid [GO:0019013]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d2jxoa1_d2h2ba1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]; beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell projection [GO:0042995]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein-containing complex assembly [GO:0065003]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of cell migration [GO:0030335]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]	beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]	cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]
d2jxxa__d2o6ve___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; cytokine production [GO:0001816]; positive regulation of transcription by RNA polymerase II [GO:0045944]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytokine production [GO:0001816]; positive regulation of transcription by RNA polymerase II [GO:0045944]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]		protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2jyla__d1eoqa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]; aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral procapsid maturation [GO:0046797]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral procapsid maturation [GO:0046797]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d2jz3c__d1qdvb___1	Metazoa	Metazoa	Chordata	Chordata	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	ubiquitin protein ligase binding [GO:0031625]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]
d2jzla__d2l2fa___1	Fungi	Fungi	Ascomycota	Ascomycota	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d2jzna__d3lfhf___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]; glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]	integral component of membrane [GO:0016021]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]	transferase activity [GO:0016740]
d2jznb__d3lfhb1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]; glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]	integral component of membrane [GO:0016021]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]	transferase activity [GO:0016740]
d2jzoa__d3ipra___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]; glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]	integral component of membrane [GO:0016021]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]	metal ion binding [GO:0046872]
d2jzob__d2jzna___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]; glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]; glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]
d2jzob__d3ipre___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]; glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]	integral component of membrane [GO:0016021]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]	metal ion binding [GO:0046872]
d2jzra__d4fh8c___1		Metazoa	Proteobacteria	Nematoda (roundworms)	cell [GO:0005623]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; cell redox homeostasis [GO:0045454]; cellular protein modification process [GO:0006464]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular protein modification process [GO:0006464]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]	peroxiredoxin activity [GO:0051920]
d2k00a1_d1gg3a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; ruffle [GO:0001726]; carbohydrate binding [GO:0030246]; hyaluronic acid binding [GO:0005540]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]		actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; ruffle [GO:0001726]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	carbohydrate binding [GO:0030246]; hyaluronic acid binding [GO:0005540]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]
d2k07a1_d2ebka1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; UFM1 conjugating enzyme activity [GO:0061657]; UFM1 transferase activity [GO:0071568]; brain development [GO:0007420]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; response to endoplasmic reticulum stress [GO:0034976]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902073]; positive regulation of protein sumoylation [GO:0033235]	brain development [GO:0007420]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; response to endoplasmic reticulum stress [GO:0034976]	negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902073]; positive regulation of protein sumoylation [GO:0033235]	extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	UFM1 conjugating enzyme activity [GO:0061657]; UFM1 transferase activity [GO:0071568]	
d2k0ea__d4ndbb___1	Metazoa	Metazoa	Chordata	Mollusca	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	metal ion binding [GO:0046872]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]		adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	metal ion binding [GO:0046872]
d2k0ga1_d4a2ub1__1			Proteobacteria	Actinobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]		negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2k20a__d4n6xa1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; axonal growth cone [GO:0044295]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell cortex [GO:0005938]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; endomembrane system [GO:0012505]; internode region of axon [GO:0033269]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein phosphatase binding [GO:0019903]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; protein localization [GO:0008104]; protein targeting to membrane [GO:0006612]; regulation of cellular localization [GO:0060341]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]; beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; protein localization [GO:0008104]; protein targeting to membrane [GO:0006612]; regulation of cellular localization [GO:0060341]	actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein-containing complex assembly [GO:0065003]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; axonal growth cone [GO:0044295]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; endomembrane system [GO:0012505]; internode region of axon [GO:0033269]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]	identical protein binding [GO:0042802]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol binding [GO:0035091]; protein phosphatase binding [GO:0019903]	beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]
d2k23a__d4orub___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to bacterium [GO:0009617]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to nutrient levels [GO:0031667]; response to oxidative stress [GO:0006979]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to bacterium [GO:0009617]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to nutrient levels [GO:0031667]; response to oxidative stress [GO:0006979]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	cell [GO:0005623]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d2k2fa__d1pvba___1	Metazoa	Metazoa	Chordata	Chordata	A band [GO:0031672]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; I band [GO:0031674]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]; calcium ion binding [GO:0005509]	negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]		A band [GO:0031672]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; I band [GO:0031674]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]	calcium ion binding [GO:0005509]
d2k3sa1_d4q59a1__1	Metazoa	Metazoa	Chordata	Chordata	contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; I band [GO:0031674]; M band [GO:0031430]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; calmodulin binding [GO:0005516]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin phosphatase regulator activity [GO:0017020]; protein phosphatase 1 binding [GO:0008157]; protein phosphatase inhibitor activity [GO:0004864]; protein self-association [GO:0043621]; tropomyosin binding [GO:0005523]; actin cytoskeleton organization [GO:0030036]; muscle organ morphogenesis [GO:0048644]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to drug [GO:0042493]	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	actin cytoskeleton organization [GO:0030036]; muscle organ morphogenesis [GO:0048644]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to drug [GO:0042493]	hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; I band [GO:0031674]; M band [GO:0031430]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	calmodulin binding [GO:0005516]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin phosphatase regulator activity [GO:0017020]; protein phosphatase 1 binding [GO:0008157]; protein phosphatase inhibitor activity [GO:0004864]; protein self-association [GO:0043621]; tropomyosin binding [GO:0005523]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]
d2k3sb1_d2k8mc___1	Metazoa	Metazoa	Chordata	Chordata	contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; I band [GO:0031674]; M band [GO:0031430]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; calmodulin binding [GO:0005516]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin phosphatase regulator activity [GO:0017020]; protein phosphatase 1 binding [GO:0008157]; protein phosphatase inhibitor activity [GO:0004864]; protein self-association [GO:0043621]; tropomyosin binding [GO:0005523]; actin cytoskeleton organization [GO:0030036]; muscle organ morphogenesis [GO:0048644]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	actin cytoskeleton organization [GO:0030036]; muscle organ morphogenesis [GO:0048644]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to drug [GO:0042493]	cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; I band [GO:0031674]; M band [GO:0031430]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	calmodulin binding [GO:0005516]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin phosphatase regulator activity [GO:0017020]; protein phosphatase 1 binding [GO:0008157]; protein phosphatase inhibitor activity [GO:0004864]; protein self-association [GO:0043621]; tropomyosin binding [GO:0005523]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d2k43a__d1cvsa___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]
d2k45a__d5bzzc2__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; clathrin-coated vesicle membrane [GO:0030665]; clathrin-sculpted acetylcholine transport vesicle membrane [GO:0060201]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; clathrin-sculpted glutamate transport vesicle membrane [GO:0060203]; clathrin-sculpted monoamine transport vesicle membrane [GO:0070083]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; 1-phosphatidylinositol binding [GO:0005545]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; glutamate secretion [GO:0014047]; membrane organization [GO:0061024]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of exocytosis [GO:0017157]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; ubiquitin-specific protease binding [GO:1990381]; adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; glutamate secretion [GO:0014047]; membrane organization [GO:0061024]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of exocytosis [GO:0017157]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; clathrin-coated vesicle membrane [GO:0030665]; clathrin-sculpted acetylcholine transport vesicle membrane [GO:0060201]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; clathrin-sculpted glutamate transport vesicle membrane [GO:0060203]; clathrin-sculpted monoamine transport vesicle membrane [GO:0070083]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	1-phosphatidylinositol binding [GO:0005545]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]	anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381]
d2k4ab__d1tooa___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d2k4ab__d3k1xb___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2k4ia__d1hiwb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2k4ia__d1uhua1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d2k4ja1_d1gxpb___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]	bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2k5ga1_d4mapb___1		Viridiplantae	Proteobacteria	Streptophyta		abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]				abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2k5xa__d2gyke___1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	protein-containing complex [GO:0032991]	protein-containing complex [GO:0032991]	protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]
d2k5xb1_d4uhpe___1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	protein-containing complex [GO:0032991]		protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	toxic substance binding [GO:0015643]
d2k62a__d3elza1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	bile acid binding [GO:0032052]; lipid binding [GO:0008289]			cytoplasm [GO:0005737]		lipid binding [GO:0008289]	bile acid binding [GO:0032052]; lipid binding [GO:0008289]
d2k7ja1_d4ojha___1	Metazoa		Chordata	Crenarchaeota	acylphosphatase activity [GO:0003998]; phosphate-containing compound metabolic process [GO:0006796]	acylphosphatase activity [GO:0003998]	phosphate-containing compound metabolic process [GO:0006796]				acylphosphatase activity [GO:0003998]	acylphosphatase activity [GO:0003998]
d2k7ka1_d2bjdb___1	Metazoa		Chordata	Crenarchaeota	acylphosphatase activity [GO:0003998]; phosphate-containing compound metabolic process [GO:0006796]	acylphosphatase activity [GO:0003998]	phosphate-containing compound metabolic process [GO:0006796]				acylphosphatase activity [GO:0003998]	acylphosphatase activity [GO:0003998]
d2k7oa__d1alva___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; proteolysis [GO:0006508]	astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	proteolysis [GO:0006508]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d2k7ob__d2l51b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; response to calcium ion [GO:0051592]	astrocyte differentiation [GO:0048708]; cellular response to hypoxia [GO:0071456]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	response to calcium ion [GO:0051592]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d2k8ba__d4p5ok___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2k8ba__d5j2ra___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; activation of MAPKK activity [GO:0000186]; animal organ morphogenesis [GO:0009887]; cellular response to calcium ion [GO:0071277]; establishment of protein localization to membrane [GO:0090150]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein phosphorylation [GO:0006468]; trehalose metabolism in response to stress [GO:0070413]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPKK activity [GO:0000186]; animal organ morphogenesis [GO:0009887]; cellular response to calcium ion [GO:0071277]; establishment of protein localization to membrane [GO:0090150]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein phosphorylation [GO:0006468]; trehalose metabolism in response to stress [GO:0070413]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d2k8mb__d4j9zr___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; small conductance calcium-activated potassium channel activity [GO:0016286]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of neuronal synaptic plasticity [GO:0048168]	cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of neuronal synaptic plasticity [GO:0048168]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calmodulin binding [GO:0005516]; small conductance calcium-activated potassium channel activity [GO:0016286]
d2k8mc__d2ggzb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	photoreceptor disc membrane [GO:0097381]; calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; signal transduction [GO:0007165]; visual perception [GO:0007601]	cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	regulation of rhodopsin mediated signaling pathway [GO:0022400]; signal transduction [GO:0007165]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	photoreceptor disc membrane [GO:0097381]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048]
d2k8md1_d5ccjd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]
d2k9fa__d2eird___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; integral component of plasma membrane [GO:0005887]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; integral component of plasma membrane [GO:0005887]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2kaxa__d1xk4k___1	Metazoa	Metazoa	Chordata	Chordata	neuronal cell body [GO:0043025]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	neuronal cell body [GO:0043025]; nucleus [GO:0005634]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d2kaxb__d2lp2a___1	Metazoa	Metazoa	Chordata	Chordata	neuronal cell body [GO:0043025]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]		intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	neuronal cell body [GO:0043025]; nucleus [GO:0005634]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]
d2kaya__d1a75a___1	Metazoa	Metazoa	Chordata	Chordata	neuronal cell body [GO:0043025]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]			neuronal cell body [GO:0043025]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]
d2kaya__d2l51a___1	Metazoa	Metazoa	Chordata	Chordata	neuronal cell body [GO:0043025]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; response to calcium ion [GO:0051592]		response to calcium ion [GO:0051592]	neuronal cell body [GO:0043025]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d2kb0a__d2wwhb___1	Metazoa		Chordata	Apicomplexa	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]
d2kb0a__d3rs0a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d2kbea__d4asuf2__1	Fungi	Metazoa	Ascomycota	Chordata	cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nuclear membrane [GO:0031965]; nuclear pore cytoplasmic filaments [GO:0044614]; nucleus [GO:0005634]; polysome [GO:0005844]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-dependent ATPase activity [GO:0008186]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; translational termination [GO:0006415]; tRNA export from nucleus [GO:0006409]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; translational termination [GO:0006415]; tRNA export from nucleus [GO:0006409]	ATP synthesis coupled proton transport [GO:0015986]	cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nuclear membrane [GO:0031965]; nuclear pore cytoplasmic filaments [GO:0044614]; nucleus [GO:0005634]; polysome [GO:0005844]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; RNA helicase activity [GO:0003724]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2kbga__d3qwqb___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; integral component of membrane [GO:0016021]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; axonal fasciculation [GO:0007413]; neuron cell-cell adhesion [GO:0007158]; sensory perception of smell [GO:0007608]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	axonal fasciculation [GO:0007413]; neuron cell-cell adhesion [GO:0007158]; sensory perception of smell [GO:0007608]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	axon [GO:0030424]; integral component of membrane [GO:0016021]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	identical protein binding [GO:0042802]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2kbma__d1dmoa___1	Metazoa	Metazoa	Chordata	Chordata	actin cortical patch [GO:0030479]; brush border [GO:0005903]; F-actin capping protein complex [GO:0008290]; membrane [GO:0016020]; actin filament binding [GO:0051015]; actin cytoskeleton organization [GO:0030036]; barbed-end actin filament capping [GO:0051016]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	actin cytoskeleton organization [GO:0030036]; barbed-end actin filament capping [GO:0051016]	calcium-mediated signaling [GO:0019722]	actin cortical patch [GO:0030479]; brush border [GO:0005903]; F-actin capping protein complex [GO:0008290]; membrane [GO:0016020]		actin filament binding [GO:0051015]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]
d2kbmb__d3c1va___1	Metazoa	Metazoa	Chordata	Chordata	actin cortical patch [GO:0030479]; brush border [GO:0005903]; F-actin capping protein complex [GO:0008290]; membrane [GO:0016020]; actin filament binding [GO:0051015]; actin cytoskeleton organization [GO:0030036]; barbed-end actin filament capping [GO:0051016]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	actin cytoskeleton organization [GO:0030036]; barbed-end actin filament capping [GO:0051016]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	actin cortical patch [GO:0030479]; brush border [GO:0005903]; F-actin capping protein complex [GO:0008290]; membrane [GO:0016020]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	actin filament binding [GO:0051015]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d2kboa1_d1ysda1__1	Metazoa	Fungi	Chordata	Ascomycota	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]
d2kbsa__d2zleg1__1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; microvillus [GO:0005902]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; stereocilia ankle link [GO:0002141]; stereocilia ankle link complex [GO:0002142]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426]; synapse [GO:0045202]; actin filament binding [GO:0051015]; spectrin binding [GO:0030507]; actin filament bundle assembly [GO:0051017]; brush border assembly [GO:1904970]; cellular protein-containing complex assembly [GO:0034622]; equilibrioception [GO:0050957]; G2/M transition of mitotic cell cycle [GO:0000086]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell stereocilium organization [GO:0060122]; parallel actin filament bundle assembly [GO:0030046]; photoreceptor cell maintenance [GO:0045494]; protein localization to microvillus [GO:1904106]; regulation of microvillus length [GO:0032532]; retinal cone cell development [GO:0046549]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	actin filament bundle assembly [GO:0051017]; brush border assembly [GO:1904970]; cellular protein-containing complex assembly [GO:0034622]; equilibrioception [GO:0050957]; G2/M transition of mitotic cell cycle [GO:0000086]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell stereocilium organization [GO:0060122]; parallel actin filament bundle assembly [GO:0030046]; photoreceptor cell maintenance [GO:0045494]; protein localization to microvillus [GO:1904106]; regulation of microvillus length [GO:0032532]; retinal cone cell development [GO:0046549]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; microvillus [GO:0005902]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; stereocilia ankle link [GO:0002141]; stereocilia ankle link complex [GO:0002142]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426]; synapse [GO:0045202]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; spectrin binding [GO:0030507]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2kbxa__d5d66b2__1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; cell-cell junction [GO:0005911]; costamere [GO:0043034]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; stress fiber [GO:0001725]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; integrin binding [GO:0005178]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; SH3 domain binding [GO:0017124]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell junction assembly [GO:0034329]; cell population proliferation [GO:0008283]; cell-matrix adhesion [GO:0007160]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; fibroblast migration [GO:0010761]; integrin-mediated signaling pathway [GO:0007229]; myelin assembly [GO:0032288]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; outflow tract morphogenesis [GO:0003151]; peptidyl-serine phosphorylation [GO:0018105]; platelet aggregation [GO:0070527]; positive regulation of axon extension [GO:0045773]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of signal transduction [GO:0009967]; positive regulation of transcription, DNA-templated [GO:0045893]; protein heterooligomerization [GO:0051291]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; substrate adhesion-dependent cell spreading [GO:0034446]; supramolecular fiber organization [GO:0097435]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	integral component of membrane [GO:0016021]	branching involved in ureteric bud morphogenesis [GO:0001658]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell population proliferation [GO:0008283]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; fibroblast migration [GO:0010761]; integrin-mediated signaling pathway [GO:0007229]; myelin assembly [GO:0032288]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; outflow tract morphogenesis [GO:0003151]; peptidyl-serine phosphorylation [GO:0018105]; platelet aggregation [GO:0070527]; positive regulation of axon extension [GO:0045773]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of signal transduction [GO:0009967]; positive regulation of transcription, DNA-templated [GO:0045893]; protein heterooligomerization [GO:0051291]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; substrate adhesion-dependent cell spreading [GO:0034446]; supramolecular fiber organization [GO:0097435]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		cell-cell junction [GO:0005911]; cell junction [GO:0030054]; costamere [GO:0043034]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; stress fiber [GO:0001725]; terminal bouton [GO:0043195]	integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; integrin binding [GO:0005178]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; SH3 domain binding [GO:0017124]	
d2kcja1_d1m7ec___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; ceramide 1-phosphate binding [GO:1902387]; ceramide 1-phosphate transfer activity [GO:1902388]; lipid binding [GO:0008289]; phosphatidylinositol-4-phosphate binding [GO:0070273]; ceramide transport [GO:0035627]; ER to Golgi ceramide transport [GO:0035621]; intermembrane lipid transfer [GO:0120009]; phosphatidylinositol biosynthetic process [GO:0006661]	apical plasma membrane [GO:0016324]; clathrin coat of coated pit [GO:0030132]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]; activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	ceramide transport [GO:0035627]; ER to Golgi ceramide transport [GO:0035621]; intermembrane lipid transfer [GO:0120009]; phosphatidylinositol biosynthetic process [GO:0006661]	activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; hematopoietic stem cell proliferation [GO:0071425]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of aldosterone biosynthetic process [GO:0032349]; positive regulation of aldosterone secretion [GO:2000860]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of Rho-dependent protein serine/threonine kinase activity [GO:2000298]; response to steroid hormone [GO:0048545]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]	apical plasma membrane [GO:0016324]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; clathrin-coated vesicle membrane [GO:0030665]; clathrin coat of coated pit [GO:0030132]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	ceramide 1-phosphate binding [GO:1902387]; ceramide 1-phosphate transfer activity [GO:1902388]; lipid binding [GO:0008289]; phosphatidylinositol-4-phosphate binding [GO:0070273]	AP-2 adaptor complex binding [GO:0035612]; cargo receptor activity [GO:0038024]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; integrin binding [GO:0005178]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol binding [GO:0035091]; protein C-terminus binding [GO:0008022]; SMAD binding [GO:0046332]
d2kd5a1_d1tmwa___1		Metazoa		Chordata		cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; site of polarized growth [GO:0030427]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]; defense response to fungus [GO:0050832]; neutrophil degranulation [GO:0043312]; regulation of actin filament polymerization [GO:0030833]		defense response to fungus [GO:0050832]; neutrophil degranulation [GO:0043312]; regulation of actin filament polymerization [GO:0030833]		cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; site of polarized growth [GO:0030427]		actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]
d2kd5a1_d2xfaa___1				Apicomplexa		actin cytoskeleton [GO:0015629]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]		actin filament depolymerization [GO:0030042]		actin cytoskeleton [GO:0015629]		actin binding [GO:0003779]
d2kdfc__d2klca___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	aggresome [GO:0016235]; autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; polyubiquitin modification-dependent protein binding [GO:0031593]; aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; cellular response to hypoxia [GO:0071456]; macroautophagy [GO:0016236]; negative regulation of store-operated calcium channel activity [GO:1901340]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of protein ubiquitination [GO:0031398]; regulation of macroautophagy [GO:0016241]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; regulation of protein ubiquitination [GO:0031396]; response to endoplasmic reticulum stress [GO:0034976]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; cellular response to hypoxia [GO:0071456]; macroautophagy [GO:0016236]; negative regulation of store-operated calcium channel activity [GO:1901340]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of protein ubiquitination [GO:0031398]; regulation of macroautophagy [GO:0016241]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; regulation of protein ubiquitination [GO:0031396]; response to endoplasmic reticulum stress [GO:0034976]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	aggresome [GO:0016235]; autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; polyubiquitin modification-dependent protein binding [GO:0031593]
d2ke5a__d1iqpb2__1	Metazoa		Chordata	Euryarchaeota	extracellular exosome [GO:0070062]; midbody [GO:0030496]; plasma membrane [GO:0005886]; ATPase binding [GO:0051117]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to starvation [GO:0009267]; negative regulation of protein binding [GO:0032091]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; Ras protein signal transduction [GO:0007265]; regulation of exocyst assembly [GO:0001928]; regulation of exocyst localization [GO:0060178]; signal transduction [GO:0007165]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to starvation [GO:0009267]; negative regulation of protein binding [GO:0032091]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; Ras protein signal transduction [GO:0007265]; regulation of exocyst assembly [GO:0001928]; regulation of exocyst localization [GO:0060178]; signal transduction [GO:0007165]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	extracellular exosome [GO:0070062]; midbody [GO:0030496]; plasma membrane [GO:0005886]		ATPase binding [GO:0051117]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]
d2kepa__d3njeb___1			Proteobacteria	Proteobacteria	type II protein secretion system complex [GO:0015627]; protein secretion by the type II secretion system [GO:0015628]	type II protein secretion system complex [GO:0015627]; protein secretion by the type II secretion system [GO:0015628]	protein secretion by the type II secretion system [GO:0015628]	protein secretion by the type II secretion system [GO:0015628]	type II protein secretion system complex [GO:0015627]	type II protein secretion system complex [GO:0015627]		
d2kewa1_d4hm3a2__1			Firmicutes	Proteobacteria		dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]				dioxygenase activity [GO:0051213]
d2kf6a__d3hohc___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d2kfja1_d1f2rc___1	Fungi	Metazoa	Ascomycota	Chordata	Cdc24p-Far1p-Gbetagamma complex [GO:0120171]; cell division site [GO:0032153]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; division septum [GO:0000935]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]; nucleus [GO:0005634]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; cellular bud site selection [GO:0000282]; chemotropism [GO:0043577]; protein localization to cell cortex [GO:0072697]; regulation of exit from mitosis [GO:0007096]; regulation of Rho protein signal transduction [GO:0035023]; septin ring organization [GO:0031106]; small GTPase mediated signal transduction [GO:0007264]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; deoxyribonuclease activity [GO:0004536]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclease activity [GO:0004518]; protein domain specific binding [GO:0019904]; apoptotic chromosome condensation [GO:0030263]; apoptotic DNA fragmentation [GO:0006309]; DNA catabolic process [GO:0006308]; protein homooligomerization [GO:0051260]	cellular bud site selection [GO:0000282]; chemotropism [GO:0043577]; protein localization to cell cortex [GO:0072697]; regulation of exit from mitosis [GO:0007096]; regulation of Rho protein signal transduction [GO:0035023]; septin ring organization [GO:0031106]; small GTPase mediated signal transduction [GO:0007264]	apoptotic chromosome condensation [GO:0030263]; apoptotic DNA fragmentation [GO:0006309]; DNA catabolic process [GO:0006308]; protein homooligomerization [GO:0051260]	Cdc24p-Far1p-Gbetagamma complex [GO:0120171]; cell division site [GO:0032153]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; division septum [GO:0000935]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]; nucleus [GO:0005634]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	Rho guanyl-nucleotide exchange factor activity [GO:0005089]	deoxyribonuclease activity [GO:0004536]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclease activity [GO:0004518]; protein domain specific binding [GO:0019904]
d2kfkb1_d1d4ba1__1	Fungi	Metazoa	Ascomycota	Chordata	Cdc24p-Far1p-Gbetagamma complex [GO:0120171]; cell division site [GO:0032153]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; division septum [GO:0000935]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]; nucleus [GO:0005634]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; cellular bud site selection [GO:0000282]; chemotropism [GO:0043577]; protein localization to cell cortex [GO:0072697]; regulation of exit from mitosis [GO:0007096]; regulation of Rho protein signal transduction [GO:0035023]; septin ring organization [GO:0031106]; small GTPase mediated signal transduction [GO:0007264]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; perinuclear region of cytoplasm [GO:0048471]; identical protein binding [GO:0042802]; activation of cysteine-type endopeptidase activity [GO:0097202]; apoptotic process [GO:0006915]; execution phase of apoptosis [GO:0097194]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; positive regulation of cell death [GO:0010942]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]	cellular bud site selection [GO:0000282]; chemotropism [GO:0043577]; protein localization to cell cortex [GO:0072697]; regulation of exit from mitosis [GO:0007096]; regulation of Rho protein signal transduction [GO:0035023]; septin ring organization [GO:0031106]; small GTPase mediated signal transduction [GO:0007264]	activation of cysteine-type endopeptidase activity [GO:0097202]; apoptotic process [GO:0006915]; execution phase of apoptosis [GO:0097194]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; positive regulation of cell death [GO:0010942]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]	Cdc24p-Far1p-Gbetagamma complex [GO:0120171]; cell division site [GO:0032153]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; division septum [GO:0000935]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]; nucleus [GO:0005634]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; perinuclear region of cytoplasm [GO:0048471]	Rho guanyl-nucleotide exchange factor activity [GO:0005089]	identical protein binding [GO:0042802]
d2kfoa1_d1y15a___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of catalytic activity [GO:0043086]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization [GO:0032880]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to oxidative stress [GO:0006979]	anchored component of membrane [GO:0031225]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of catalytic activity [GO:0043086]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization [GO:0032880]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to oxidative stress [GO:0006979]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of catalytic activity [GO:0043086]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization [GO:0032880]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to oxidative stress [GO:0006979]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of catalytic activity [GO:0043086]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization [GO:0032880]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to oxidative stress [GO:0006979]	anchored component of membrane [GO:0031225]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	anchored component of membrane [GO:0031225]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d2kfxt__d5g58a___1	Metazoa	Metazoa	Chordata	Chordata	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendrite membrane [GO:0032590]; dendritic spine head [GO:0044327]; extrinsic component of membrane [GO:0019898]; glutamatergic synapse [GO:0098978]; neuronal cell body membrane [GO:0032809]; perikaryon [GO:0043204]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; activation of phospholipase D activity [GO:0031584]; brain development [GO:0007420]; calcium-mediated signaling [GO:0019722]; cellular response to calcium ion [GO:0071277]; cellular response to electrical stimulus [GO:0071257]; cellular response to monosodium glutamate [GO:1904009]; inner ear development [GO:0048839]; negative regulation of guanylate cyclase activity [GO:0031283]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to Aroclor 1254 [GO:1904010]; response to ketamine [GO:1901986]; response to L-glutamate [GO:1902065]; retina development in camera-type eye [GO:0060041]	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	activation of phospholipase D activity [GO:0031584]; brain development [GO:0007420]; calcium-mediated signaling [GO:0019722]; cellular response to calcium ion [GO:0071277]; cellular response to electrical stimulus [GO:0071257]; cellular response to monosodium glutamate [GO:1904009]; inner ear development [GO:0048839]; negative regulation of guanylate cyclase activity [GO:0031283]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to Aroclor 1254 [GO:1904010]; response to ketamine [GO:1901986]; response to L-glutamate [GO:1902065]; retina development in camera-type eye [GO:0060041]	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendrite membrane [GO:0032590]; dendritic spine head [GO:0044327]; extrinsic component of membrane [GO:0019898]; glutamatergic synapse [GO:0098978]; neuronal cell body membrane [GO:0032809]; perikaryon [GO:0043204]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]
d2kg2a1_d3gslb1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]; activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]
d2khsa__d5cr3a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2ki6c__d2l0pb___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]
d2ki6e__d2hwaa1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2kjca__d1r22b___1			Firmicutes	Cyanobacteria	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]					DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]
d2kjra1_d5chwj1__1	Metazoa	Metazoa	Arthropoda	Chordata	cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; cytoplasmic microtubule organization [GO:0031122]; establishment of apical/basal cell polarity [GO:0035089]; oocyte axis specification [GO:0007309]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cytoplasmic microtubule organization [GO:0031122]; establishment of apical/basal cell polarity [GO:0035089]; oocyte axis specification [GO:0007309]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]		integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2kkqa1_d4gftb___1	Metazoa		Chordata	Apicomplexa	actin cytoskeleton [GO:0015629]; axon [GO:0030424]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; axon guidance receptor activity [GO:0008046]; structural constituent of muscle [GO:0008307]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; muscle contraction [GO:0006936]; synapse organization [GO:0050808]	inner membrane pellicle complex [GO:0070258]; calcium ion binding [GO:0005509]	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; muscle contraction [GO:0006936]; synapse organization [GO:0050808]		actin cytoskeleton [GO:0015629]; axon [GO:0030424]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]	inner membrane pellicle complex [GO:0070258]	actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; axon guidance receptor activity [GO:0008046]; structural constituent of muscle [GO:0008307]	calcium ion binding [GO:0005509]
d2klfa__d3fv2b___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2klsa1_d3e9ua1__1		Metazoa		Arthropoda		integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]; calcium:sodium antiporter activity [GO:0005432]; neuromuscular process controlling posture [GO:0050884]; phototransduction [GO:0007602]; response to endoplasmic reticulum stress [GO:0034976]		neuromuscular process controlling posture [GO:0050884]; phototransduction [GO:0007602]; response to endoplasmic reticulum stress [GO:0034976]		integral component of membrane [GO:0016021]		calcium:sodium antiporter activity [GO:0005432]; calcium ion binding [GO:0005509]
d2km2a__d3nwka___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2km8b__d1x5ta1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U2-type precatalytic spliceosome [GO:0071005]; RNA binding [GO:0003723]; splicing factor binding [GO:1990935]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]	mRNA polyadenylation [GO:0006378]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U2-type precatalytic spliceosome [GO:0071005]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	RNA binding [GO:0003723]; splicing factor binding [GO:1990935]
d2km8c1_d2up1a1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	mRNA polyadenylation [GO:0006378]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]
d2km8c1_d4ckoe4__1	Fungi		Ascomycota		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]		mRNA polyadenylation [GO:0006378]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]		mRNA binding [GO:0003729]; RNA binding [GO:0003723]	
d2km8c2_d2mqoa___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; ribonucleoprotein complex [GO:1990904]; ribonucleoprotein granule [GO:0035770]; mRNA 3'-UTR binding [GO:0003730]; mRNA CDS binding [GO:1990715]; pre-mRNA intronic binding [GO:0097157]; transcription regulatory region DNA binding [GO:0044212]; cellular response to amino acid starvation [GO:0034198]; circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to peptide [GO:1901652]	mRNA polyadenylation [GO:0006378]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	cellular response to amino acid starvation [GO:0034198]; circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to peptide [GO:1901652]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; ribonucleoprotein complex [GO:1990904]; ribonucleoprotein granule [GO:0035770]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	mRNA 3'-UTR binding [GO:0003730]; mRNA CDS binding [GO:1990715]; pre-mRNA intronic binding [GO:0097157]; transcription regulatory region DNA binding [GO:0044212]
d2kmta__d4mzma1__1			Proteobacteria	Firmicutes	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity [GO:0008657]; plasmid maintenance [GO:0006276]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; RNA binding [GO:0003723]	plasmid maintenance [GO:0006276]				DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity [GO:0008657]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; RNA binding [GO:0003723]
d2kmya__d2bpna___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]		anaerobic respiration [GO:0009061]		periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2kn2a1_d2zrsc___1	Viridiplantae	Metazoa	Streptophyta	Chordata	calcium ion binding [GO:0005509]; calcium-mediated signaling [GO:0019722]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	calcium-mediated signaling [GO:0019722]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]		COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]
d2kn5a__d5jzeb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2knba__d2io0b2__1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular vesicle [GO:0097708]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; ubiquitin ligase complex [GO:0000151]; cullin family protein binding [GO:0097602]; F-box domain binding [GO:1990444]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; adult locomotory behavior [GO:0008344]; aggresome assembly [GO:0070842]; autophagy of mitochondrion [GO:0000422]; brain development [GO:0007420]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to L-glutamate [GO:1905232]; cellular response to L-glutamine [GO:1904845]; cellular response to manganese ion [GO:0071287]; cellular response to toxic substance [GO:0097237]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676]; negative regulation of JNK cascade [GO:0046329]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron cellular homeostasis [GO:0070050]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of DNA binding [GO:0043388]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of mitophagy [GO:1901526]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K6-linked ubiquitination [GO:0085020]; protein K63-linked ubiquitination [GO:0070534]; protein localization to mitochondrion [GO:0070585]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of gene expression [GO:0010468]; regulation of mitochondrion organization [GO:0010821]; response to corticosterone [GO:0051412]; response to curcumin [GO:1904643]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to muscle activity [GO:0014850]; response to oxidative stress [GO:0006979]; response to unfolded protein [GO:0006986]; ubiquitin-dependent protein catabolic process [GO:0006511]; zinc ion homeostasis [GO:0055069]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein domain specific binding [GO:0019904]; SUMO-specific endopeptidase activity [GO:0070139]; SUMO-specific isopeptidase activity [GO:0070140]; dorsal/ventral axis specification [GO:0009950]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; labyrinthine layer development [GO:0060711]; mRNA transport [GO:0051028]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of DNA endoreduplication [GO:0032875]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of Wnt signaling pathway [GO:0030111]; spongiotrophoblast layer development [GO:0060712]; trophoblast giant cell differentiation [GO:0060707]; Wnt signaling pathway [GO:0016055]	adult locomotory behavior [GO:0008344]; aggresome assembly [GO:0070842]; autophagy of mitochondrion [GO:0000422]; brain development [GO:0007420]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to L-glutamate [GO:1905232]; cellular response to L-glutamine [GO:1904845]; cellular response to manganese ion [GO:0071287]; cellular response to toxic substance [GO:0097237]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676]; negative regulation of JNK cascade [GO:0046329]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron cellular homeostasis [GO:0070050]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of DNA binding [GO:0043388]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of mitophagy [GO:1901526]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein localization to mitochondrion [GO:0070585]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of gene expression [GO:0010468]; regulation of mitochondrion organization [GO:0010821]; response to corticosterone [GO:0051412]; response to curcumin [GO:1904643]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to muscle activity [GO:0014850]; response to oxidative stress [GO:0006979]; response to unfolded protein [GO:0006986]; ubiquitin-dependent protein catabolic process [GO:0006511]; zinc ion homeostasis [GO:0055069]	dorsal/ventral axis specification [GO:0009950]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; labyrinthine layer development [GO:0060711]; mRNA transport [GO:0051028]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of DNA endoreduplication [GO:0032875]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of Wnt signaling pathway [GO:0030111]; spongiotrophoblast layer development [GO:0060712]; trophoblast giant cell differentiation [GO:0060707]; Wnt signaling pathway [GO:0016055]	aggresome [GO:0016235]; axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular vesicle [GO:0097708]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; ubiquitin ligase complex [GO:0000151]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	cullin family protein binding [GO:0097602]; F-box domain binding [GO:1990444]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]	protein domain specific binding [GO:0019904]; SUMO-specific endopeptidase activity [GO:0070139]; SUMO-specific isopeptidase activity [GO:0070140]
d2knba__d5aekh___1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular vesicle [GO:0097708]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; ubiquitin ligase complex [GO:0000151]; cullin family protein binding [GO:0097602]; F-box domain binding [GO:1990444]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; adult locomotory behavior [GO:0008344]; aggresome assembly [GO:0070842]; autophagy of mitochondrion [GO:0000422]; brain development [GO:0007420]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to L-glutamate [GO:1905232]; cellular response to L-glutamine [GO:1904845]; cellular response to manganese ion [GO:0071287]; cellular response to toxic substance [GO:0097237]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676]; negative regulation of JNK cascade [GO:0046329]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron cellular homeostasis [GO:0070050]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of DNA binding [GO:0043388]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of mitophagy [GO:1901526]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K6-linked ubiquitination [GO:0085020]; protein K63-linked ubiquitination [GO:0070534]; protein localization to mitochondrion [GO:0070585]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of gene expression [GO:0010468]; regulation of mitochondrion organization [GO:0010821]; response to corticosterone [GO:0051412]; response to curcumin [GO:1904643]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to muscle activity [GO:0014850]; response to oxidative stress [GO:0006979]; response to unfolded protein [GO:0006986]; ubiquitin-dependent protein catabolic process [GO:0006511]; zinc ion homeostasis [GO:0055069]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	adult locomotory behavior [GO:0008344]; aggresome assembly [GO:0070842]; autophagy of mitochondrion [GO:0000422]; brain development [GO:0007420]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to L-glutamate [GO:1905232]; cellular response to L-glutamine [GO:1904845]; cellular response to manganese ion [GO:0071287]; cellular response to toxic substance [GO:0097237]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676]; negative regulation of JNK cascade [GO:0046329]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron cellular homeostasis [GO:0070050]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of DNA binding [GO:0043388]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of mitophagy [GO:1901526]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein localization to mitochondrion [GO:0070585]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of gene expression [GO:0010468]; regulation of mitochondrion organization [GO:0010821]; response to corticosterone [GO:0051412]; response to curcumin [GO:1904643]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to muscle activity [GO:0014850]; response to oxidative stress [GO:0006979]; response to unfolded protein [GO:0006986]; ubiquitin-dependent protein catabolic process [GO:0006511]; zinc ion homeostasis [GO:0055069]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	aggresome [GO:0016235]; axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular vesicle [GO:0097708]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; ubiquitin ligase complex [GO:0000151]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	cullin family protein binding [GO:0097602]; F-box domain binding [GO:1990444]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d2knea__d4fqoa___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; caveola [GO:0005901]; cell [GO:0005623]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic active zone membrane [GO:0099059]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sperm flagellum [GO:0036126]; sperm principal piece [GO:0097228]; T-tubule [GO:0030315]; Z disc [GO:0030018]; ATP binding [GO:0005524]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase inhibitor activity [GO:0036487]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; protein phosphatase 2B binding [GO:0030346]; scaffold protein binding [GO:0097110]; calcium ion export [GO:1901660]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to acetylcholine [GO:1905145]; cellular response to epinephrine stimulus [GO:0071872]; flagellated sperm motility [GO:0030317]; hippocampus development [GO:0021766]; ion transmembrane transport [GO:0034220]; negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0140199]; negative regulation of arginine catabolic process [GO:1900082]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of citrulline biosynthetic process [GO:1903249]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of nitric-oxide synthase activity [GO:0051001]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of the force of heart contraction [GO:0098736]; neural retina development [GO:0003407]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of cardiac conduction [GO:1903779]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of transcription by RNA polymerase II [GO:0006357]; response to hydrostatic pressure [GO:0051599]; spermatogenesis [GO:0007283]; urinary bladder smooth muscle contraction [GO:0014832]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium ion export [GO:1901660]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to acetylcholine [GO:1905145]; cellular response to epinephrine stimulus [GO:0071872]; flagellated sperm motility [GO:0030317]; hippocampus development [GO:0021766]; ion transmembrane transport [GO:0034220]; negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0140199]; negative regulation of arginine catabolic process [GO:1900082]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of citrulline biosynthetic process [GO:1903249]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of nitric-oxide synthase activity [GO:0051001]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of the force of heart contraction [GO:0098736]; neural retina development [GO:0003407]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of cardiac conduction [GO:1903779]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of transcription by RNA polymerase II [GO:0006357]; response to hydrostatic pressure [GO:0051599]; spermatogenesis [GO:0007283]; urinary bladder smooth muscle contraction [GO:0014832]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	basolateral plasma membrane [GO:0016323]; caveola [GO:0005901]; cell [GO:0005623]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic active zone membrane [GO:0099059]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sperm flagellum [GO:0036126]; sperm principal piece [GO:0097228]; T-tubule [GO:0030315]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	ATP binding [GO:0005524]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase inhibitor activity [GO:0036487]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; protein phosphatase 2B binding [GO:0030346]; scaffold protein binding [GO:0097110]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d2ko3a__d1wgga1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; proteasome complex [GO:0000502]; synapse [GO:0045202]; endopeptidase inhibitor activity [GO:0004866]; proteasome binding [GO:0070628]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; chemical synaptic transmission [GO:0007268]; innate immune response [GO:0045087]; negative regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903070]; protein deubiquitination [GO:0016579]; regulation of chemotaxis [GO:0050920]; regulation of proteasomal protein catabolic process [GO:0061136]; ubiquitin-dependent protein catabolic process [GO:0006511]	anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	chemical synaptic transmission [GO:0007268]; innate immune response [GO:0045087]; negative regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903070]; protein deubiquitination [GO:0016579]; regulation of chemotaxis [GO:0050920]; regulation of proteasomal protein catabolic process [GO:0061136]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; proteasome complex [GO:0000502]; synapse [GO:0045202]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	endopeptidase inhibitor activity [GO:0004866]; proteasome binding [GO:0070628]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]
d2ko3a__d2d5gd1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	beta-catenin destruction complex [GO:0030877]; cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein homooligomerization [GO:0051260]; Wnt signaling pathway [GO:0016055]	anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein homooligomerization [GO:0051260]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	beta-catenin destruction complex [GO:0030877]; cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]
d2ko7a1_d2dg3a___1		Metazoa	Proteobacteria	Chordata	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]		'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]		cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]
d2koda__d3p05e2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2koka1_d4l0ub___1			Proteobacteria	Apicomplexa		cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]		peroxiredoxin activity [GO:0051920]
d2kopa__d1acpa___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]		fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	acyl carrier activity [GO:0000036]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]
d2kosa__d3ejea2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]		fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	acyl carrier activity [GO:0000036]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]
d2kotb__d1jc2a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	troponin complex [GO:0005861]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]
d2kp1a1_d1yzxa___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	protein disulfide isomerase activity [GO:0003756]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]
d2kp2a1_d4nhzc1__1	Fungi		Ascomycota	Proteobacteria	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]	transferase activity [GO:0016740]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]		protein disulfide isomerase activity [GO:0003756]	transferase activity [GO:0016740]
d2kp5a__d2a5ma2__1		Metazoa	Proteobacteria	Chordata		structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]
d2kpha__d4pt1b___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d2kpka1_d2vwra1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alpha-actinin binding [GO:0051393]; ATP binding [GO:0005524]; molecular adaptor activity [GO:0060090]; protein C-terminus binding [GO:0008022]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; positive regulation of cell-cell adhesion [GO:0022409]; protein-containing complex assembly [GO:0065003]; signal transduction [GO:0007165]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]	cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; positive regulation of cell-cell adhesion [GO:0022409]; protein-containing complex assembly [GO:0065003]; signal transduction [GO:0007165]		adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		alpha-actinin binding [GO:0051393]; ATP binding [GO:0005524]; molecular adaptor activity [GO:0060090]; protein C-terminus binding [GO:0008022]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]
d2kq7a1_d2zjdc___1	Fungi	Metazoa	Ascomycota	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; Cvt vesicle membrane [GO:0033110]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; fungal-type vacuole membrane [GO:0000329]; phagophore assembly site [GO:0000407]; vacuole-isolation membrane contact site [GO:0120095]; phosphatidylethanolamine binding [GO:0008429]; protein tag [GO:0031386]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular protein-containing complex localization [GO:0034629]; cellular response to nitrogen starvation [GO:0006995]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; membrane fusion [GO:0061025]; piecemeal microautophagy of the nucleus [GO:0034727]; protein localization to phagophore assembly site [GO:0034497]; protein targeting to vacuole involved in autophagy [GO:0071211]; regulation of macroautophagy [GO:0016241]; reticulophagy [GO:0061709]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular protein-containing complex localization [GO:0034629]; cellular response to nitrogen starvation [GO:0006995]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; membrane fusion [GO:0061025]; piecemeal microautophagy of the nucleus [GO:0034727]; protein localization to phagophore assembly site [GO:0034497]; protein targeting to vacuole involved in autophagy [GO:0071211]; regulation of macroautophagy [GO:0016241]; reticulophagy [GO:0061709]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; Cvt vesicle membrane [GO:0033110]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; fungal-type vacuole membrane [GO:0000329]; phagophore assembly site [GO:0000407]; vacuole-isolation membrane contact site [GO:0120095]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	phosphatidylethanolamine binding [GO:0008429]; protein tag [GO:0031386]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d2kqka__d5xt5d___1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]	cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]; cysteine metabolic process [GO:0006534]	cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]	cysteine metabolic process [GO:0006534]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]	cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]
d2kqua1_d1wsba___1			Cyanobacteria	Proteobacteria	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]		cell [GO:0005623]		electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2kqua1_d3uxhb___1		Metazoa	Cyanobacteria	Chordata	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d2krra2_d2dnha1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytoplasmic ribonucleoprotein granule [GO:0036464]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; DNA topoisomerase binding [GO:0044547]; identical protein binding [GO:0042802]; mRNA 5'-UTR binding [GO:0048027]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]; angiogenesis [GO:0001525]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to leukemia inhibitory factor [GO:1990830]; negative regulation of translation [GO:0017148]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	angiogenesis [GO:0001525]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to leukemia inhibitory factor [GO:1990830]; negative regulation of translation [GO:0017148]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]	mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	cell cortex [GO:0005938]; cytoplasmic ribonucleoprotein granule [GO:0036464]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	DNA topoisomerase binding [GO:0044547]; identical protein binding [GO:0042802]; mRNA 5'-UTR binding [GO:0048027]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]	mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]
d2ksca__d1f5of___1		Metazoa	Cyanobacteria	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2kspa1_d2y5id___1	Metazoa	Metazoa	Chordata	Chordata	ciliary pocket membrane [GO:0020018]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet dense tubular network membrane [GO:0031095]; recycling endosome membrane [GO:0055038]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; Rab GTPase binding [GO:0017137]; blood coagulation [GO:0007596]; cellular response to nerve growth factor stimulus [GO:1990090]; cholesterol homeostasis [GO:0042632]; cilium assembly [GO:0060271]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; neuron projection development [GO:0031175]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of myoblast fusion [GO:1901741]; protein homooligomerization [GO:0051260]; protein localization to cilium [GO:0061512]	calcium ion binding [GO:0005509]	blood coagulation [GO:0007596]; cellular response to nerve growth factor stimulus [GO:1990090]; cholesterol homeostasis [GO:0042632]; cilium assembly [GO:0060271]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; neuron projection development [GO:0031175]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of myoblast fusion [GO:1901741]; protein homooligomerization [GO:0051260]; protein localization to cilium [GO:0061512]		ciliary pocket membrane [GO:0020018]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]; platelet dense tubular network membrane [GO:0031095]; recycling endosome membrane [GO:0055038]		ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; Rab GTPase binding [GO:0017137]	calcium ion binding [GO:0005509]
d2ksxb1_d1cn4a1__1		Metazoa		Chordata		extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]		brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]		extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]		erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]
d2kt3a__d1tl5a___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; mercury (II) reductase activity [GO:0016152]; mercury ion binding [GO:0045340]; NADP binding [GO:0050661]; oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor [GO:0016668]; cell redox homeostasis [GO:0045454]; detoxification of mercury ion [GO:0050787]; metal ion transport [GO:0030001]	cell [GO:0005623]; cytosol [GO:0005829]; ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper ion binding [GO:0005507]; copper-dependent protein binding [GO:0032767]; metallochaperone activity [GO:0016530]; cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; detoxification of mercury ion [GO:0050787]; metal ion transport [GO:0030001]	cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; mercury (II) reductase activity [GO:0016152]; mercury ion binding [GO:0045340]; NADP binding [GO:0050661]; oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor [GO:0016668]	ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; metallochaperone activity [GO:0016530]
d2kt4b1_d1eioa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; arachidonic acid binding [GO:0050544]; enterobactin binding [GO:1903981]; oleic acid binding [GO:0070538]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]	cytoplasm [GO:0005737]; membrane [GO:0016020]; lipid binding [GO:0008289]; lipid transport [GO:0006869]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]	lipid transport [GO:0006869]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; membrane [GO:0016020]	arachidonic acid binding [GO:0050544]; enterobactin binding [GO:1903981]; oleic acid binding [GO:0070538]	lipid binding [GO:0008289]
d2kt4b1_d1z24a1__1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular region [GO:0005576]; arachidonic acid binding [GO:0050544]; enterobactin binding [GO:1903981]; oleic acid binding [GO:0070538]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]	extracellular region [GO:0005576]; pigment binding [GO:0031409]; protein-chromophore linkage [GO:0018298]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]	protein-chromophore linkage [GO:0018298]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	arachidonic acid binding [GO:0050544]; enterobactin binding [GO:1903981]; oleic acid binding [GO:0070538]	pigment binding [GO:0031409]
d2ktbb1_d3uvwa1__1	Metazoa	Metazoa	Chordata	Chordata	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]
d2ktbb1_d5enga___1	Metazoa	Metazoa	Chordata	Chordata	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2ktqa1_d2py5a1__1			Deinococcus-Thermus		DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]			DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]
d2ku1a1_d3gpjd___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2ku1g1_d3mi02___1			Euryarchaeota	Actinobacteria	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	threonine-type endopeptidase activity [GO:0004298]
d2ku2b1_d4qv9j___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2ku2e1_d3jsea___1			Euryarchaeota		cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	proteasome activator complex [GO:0008537]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	
d2ku2f1_d4r3oi___1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2ku4a1_d1i17a___1	Metazoa	Metazoa	Chordata	Chordata	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; protein homooligomerization [GO:0051260]	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; copper ion binding [GO:0005507]; acrosome reaction [GO:0007340]; cellular copper ion homeostasis [GO:0006878]; protein homooligomerization [GO:0051260]; single fertilization [GO:0007338]	protein homooligomerization [GO:0051260]	acrosome reaction [GO:0007340]; cellular copper ion homeostasis [GO:0006878]; protein homooligomerization [GO:0051260]; single fertilization [GO:0007338]	plasma membrane [GO:0005886]	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]	metal ion binding [GO:0046872]	copper ion binding [GO:0005507]
d2kuca1_d2hi7a1__1			Bacteroidetes	Proteobacteria	cell [GO:0005623]; isomerase activity [GO:0016853]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	isomerase activity [GO:0016853]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d2kuga__d4ndda___1	Metazoa	Metazoa	Chordata	Mollusca	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	metal ion binding [GO:0046872]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]		adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	metal ion binding [GO:0046872]
d2kv3a1_d3p5fd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; heparin binding [GO:0008201]; mannan binding [GO:2001065]; transmembrane signaling receptor activity [GO:0004888]; response to bacterium [GO:0009617]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	response to bacterium [GO:0009617]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	heparin binding [GO:0008201]; mannan binding [GO:2001065]; transmembrane signaling receptor activity [GO:0004888]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d2kvka1_d2fh4c2__1		Metazoa		Chordata	actin cytoskeleton [GO:0015629]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament depolymerization [GO:0030042]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cytoskeleton [GO:0015629]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d2kwca__d2n3ub___1	Fungi	Metazoa	Ascomycota	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; Cvt vesicle membrane [GO:0033110]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; fungal-type vacuole membrane [GO:0000329]; phagophore assembly site [GO:0000407]; vacuole-isolation membrane contact site [GO:0120095]; phosphatidylethanolamine binding [GO:0008429]; protein tag [GO:0031386]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular protein-containing complex localization [GO:0034629]; cellular response to nitrogen starvation [GO:0006995]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; membrane fusion [GO:0061025]; piecemeal microautophagy of the nucleus [GO:0034727]; protein localization to phagophore assembly site [GO:0034497]; protein targeting to vacuole involved in autophagy [GO:0071211]; regulation of macroautophagy [GO:0016241]; reticulophagy [GO:0061709]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular protein-containing complex localization [GO:0034629]; cellular response to nitrogen starvation [GO:0006995]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; membrane fusion [GO:0061025]; piecemeal microautophagy of the nucleus [GO:0034727]; protein localization to phagophore assembly site [GO:0034497]; protein targeting to vacuole involved in autophagy [GO:0071211]; regulation of macroautophagy [GO:0016241]; reticulophagy [GO:0061709]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; Cvt vesicle membrane [GO:0033110]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; fungal-type vacuole membrane [GO:0000329]; phagophore assembly site [GO:0000407]; vacuole-isolation membrane contact site [GO:0120095]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]	phosphatidylethanolamine binding [GO:0008429]; protein tag [GO:0031386]	protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d2kwub__d4eewb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic ribonucleoprotein granule [GO:0036464]; nuclear speck [GO:0016607]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; cellular response to UV-C [GO:0071494]; DNA replication [GO:0006260]; translesion synthesis [GO:0019985]	BAT3 complex [GO:0071818]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Hsp70 protein binding [GO:0030544]; identical protein binding [GO:0042802]; misfolded protein binding [GO:0051787]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ribosome binding [GO:0043022]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]; apoptotic process [GO:0006915]; brain development [GO:0007420]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; ER-associated misfolded protein catabolic process [GO:0071712]; immune response-activating cell surface receptor signaling pathway [GO:0002429]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; maintenance of unfolded protein involved in ERAD pathway [GO:1904378]; natural killer cell activation [GO:0030101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; positive regulation of ERAD pathway [GO:1904294]; proteasomal protein catabolic process [GO:0010498]; protein localization to cytosolic proteasome complex involved in ERAD pathway [GO:1904379]; protein stabilization [GO:0050821]; regulation of cell population proliferation [GO:0042127]; regulation of embryonic development [GO:0045995]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cellular response to UV-C [GO:0071494]; DNA replication [GO:0006260]; translesion synthesis [GO:0019985]	apoptotic process [GO:0006915]; brain development [GO:0007420]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; ER-associated misfolded protein catabolic process [GO:0071712]; immune response-activating cell surface receptor signaling pathway [GO:0002429]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; maintenance of unfolded protein involved in ERAD pathway [GO:1904378]; natural killer cell activation [GO:0030101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; positive regulation of ERAD pathway [GO:1904294]; proteasomal protein catabolic process [GO:0010498]; protein localization to cytosolic proteasome complex involved in ERAD pathway [GO:1904379]; protein stabilization [GO:0050821]; regulation of cell population proliferation [GO:0042127]; regulation of embryonic development [GO:0045995]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasmic ribonucleoprotein granule [GO:0036464]; nuclear speck [GO:0016607]	BAT3 complex [GO:0071818]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	Hsp70 protein binding [GO:0030544]; identical protein binding [GO:0042802]; misfolded protein binding [GO:0051787]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ribosome binding [GO:0043022]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d2kx6a__d2i9va___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d2kxfa2_d4ckoc4__1	Metazoa		Chordata		cell junction [GO:0030054]; nucleoplasm [GO:0005654]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]		apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]		cell junction [GO:0030054]; nucleoplasm [GO:0005654]		cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	
d2kxha1_d2ywka1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; nucleoplasm [GO:0005654]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]	nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; poly(U) RNA binding [GO:0008266]; protein homodimerization activity [GO:0042803]; single-stranded RNA binding [GO:0003727]; cell differentiation [GO:0030154]; cellular response to oxidative stress [GO:0034599]; mRNA processing [GO:0006397]; multicellular organism development [GO:0007275]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]	cell differentiation [GO:0030154]; cellular response to oxidative stress [GO:0034599]; mRNA processing [GO:0006397]; multicellular organism development [GO:0007275]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	cell junction [GO:0030054]; nucleoplasm [GO:0005654]	nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	poly(U) RNA binding [GO:0008266]; protein homodimerization activity [GO:0042803]; single-stranded RNA binding [GO:0003727]
d2kxha2_d2diva1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; nucleoplasm [GO:0005654]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; RNA binding [GO:0003723]; selenocysteine incorporation [GO:0001514]	apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]	selenocysteine incorporation [GO:0001514]	cell junction [GO:0030054]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d2kxnb__d1u1oa1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; cellular response to glucose stimulus [GO:0071333]; cerebral cortex regionalization [GO:0021796]; embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; protein complex oligomerization [GO:0051259]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; RNA splicing, via transesterification reactions [GO:0000375]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cellular response to glucose stimulus [GO:0071333]; cerebral cortex regionalization [GO:0021796]; embryonic brain development [GO:1990403]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; protein complex oligomerization [GO:0051259]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; RNA splicing, via transesterification reactions [GO:0000375]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cell [GO:0005623]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]
d2kz1a__d2z3qc2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; interleukin-15 receptor activity [GO:0042010]; protein kinase binding [GO:0019901]; interleukin-15-mediated signaling pathway [GO:0035723]; positive regulation of phagocytosis [GO:0050766]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	interleukin-15-mediated signaling pathway [GO:0035723]; positive regulation of phagocytosis [GO:0050766]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]	cytokine receptor activity [GO:0004896]; interleukin-15 receptor activity [GO:0042010]; protein kinase binding [GO:0019901]
d2kz1b1_d1wfua1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	chromatin [GO:0000785]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	chromatin [GO:0000785]; ciliary basal body [GO:0036064]; ciliary base [GO:0097546]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]	
d2kz1b2_d5ecjf___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714]; epithelial cell differentiation [GO:0030855]; intestinal epithelial cell differentiation [GO:0060575]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of neuron projection development [GO:0010976]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	epithelial cell differentiation [GO:0030855]; intestinal epithelial cell differentiation [GO:0060575]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of neuron projection development [GO:0010976]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	nucleus [GO:0005634]	cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]	DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714]
d2kzma1_d3nh1d___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 3'-5' exonuclease activity [GO:0008408]; 5'-3' exonuclease activity [GO:0008409]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]; 3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	base-excision repair [GO:0006284]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]	3'-5' exonuclease activity [GO:0008408]; 5'-3' exonuclease activity [GO:0008409]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]	3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d2l00b__d5gvib___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP-dependent protein binding [GO:0043008]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; ascospore formation [GO:0030437]; modification-dependent protein catabolic process [GO:0019941]; protein deubiquitination [GO:0016579]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]; translation [GO:0006412]	ascospore formation [GO:0030437]; modification-dependent protein catabolic process [GO:0019941]; protein deubiquitination [GO:0016579]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]; translation [GO:0006412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP-dependent protein binding [GO:0043008]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d2l0pb__d3psra___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]	calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d2l0qa1_d2fq2a___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]	fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		acyl carrier activity [GO:0000036]	
d2l0ua__d3jtdc___1		Metazoa		Mollusca		myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]				myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]		actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]
d2l0vb__d2ki4b___1		Metazoa		Chordata		cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]		activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]		cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]		fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2l15a__d3pgzb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA binding [GO:0003677]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; transcription antitermination factor activity, RNA binding [GO:0001072]; negative regulation of DNA-templated transcription, termination [GO:0060567]; response to cold [GO:0009409]; transcription, DNA-templated [GO:0006351]	single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]	negative regulation of DNA-templated transcription, termination [GO:0060567]; response to cold [GO:0009409]; transcription, DNA-templated [GO:0006351]	DNA replication [GO:0006260]	cytosol [GO:0005829]		DNA binding [GO:0003677]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; transcription antitermination factor activity, RNA binding [GO:0001072]	single-stranded DNA binding [GO:0003697]
d2l1ma__d3ue6f___1	Metazoa		Chordata		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; inward rectifier potassium channel complex [GO:1902937]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]; C3HC4-type RING finger domain binding [GO:0055131]; delayed rectifier potassium channel activity [GO:0005251]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]; voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1902282]; cardiac conduction [GO:0061337]; cardiac muscle contraction [GO:0060048]; cellular response to drug [GO:0035690]; membrane depolarization during action potential [GO:0086010]; membrane repolarization [GO:0086009]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; membrane repolarization during ventricular cardiac muscle cell action potential [GO:0098915]; negative regulation of potassium ion export across plasma membrane [GO:1903765]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion export across plasma membrane [GO:0097623]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of heart rate by hormone [GO:0003064]; regulation of membrane potential [GO:0042391]; regulation of membrane repolarization [GO:0060306]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; ventricular cardiac muscle cell action potential [GO:0086005]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	cardiac conduction [GO:0061337]; cardiac muscle contraction [GO:0060048]; cellular response to drug [GO:0035690]; membrane depolarization during action potential [GO:0086010]; membrane repolarization [GO:0086009]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; membrane repolarization during ventricular cardiac muscle cell action potential [GO:0098915]; negative regulation of potassium ion export across plasma membrane [GO:1903765]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion export across plasma membrane [GO:0097623]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of heart rate by hormone [GO:0003064]; regulation of membrane potential [GO:0042391]; regulation of membrane repolarization [GO:0060306]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; ventricular cardiac muscle cell action potential [GO:0086005]		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; inward rectifier potassium channel complex [GO:1902937]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]		C3HC4-type RING finger domain binding [GO:0055131]; delayed rectifier potassium channel activity [GO:0005251]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]; voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1902282]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d2l2aa1_d2l21a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin coat [GO:0030118]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; trans-Golgi network transport vesicle [GO:0030140]; transport vesicle [GO:0030133]; enzyme binding [GO:0019899]; G-protein alpha-subunit binding [GO:0001965]; identical protein binding [GO:0042802]; insulin-like growth factor binding [GO:0005520]; insulin-like growth factor II binding [GO:0031995]; insulin-like growth factor-activated receptor activity [GO:0005010]; mannose binding [GO:0005537]; phosphoprotein binding [GO:0051219]; retinoic acid binding [GO:0001972]; signaling receptor activity [GO:0038023]; animal organ regeneration [GO:0031100]; G protein-coupled receptor signaling pathway [GO:0007186]; liver development [GO:0001889]; lysosomal transport [GO:0007041]; membrane organization [GO:0061024]; neutrophil degranulation [GO:0043312]; positive regulation by host of viral process [GO:0044794]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; receptor-mediated endocytosis [GO:0006898]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]	integral component of membrane [GO:0016021]; insulin-like growth factor binding [GO:0005520]; mannose binding [GO:0005537]; signaling receptor activity [GO:0038023]; lysosomal transport [GO:0007041]	animal organ regeneration [GO:0031100]; G protein-coupled receptor signaling pathway [GO:0007186]; liver development [GO:0001889]; lysosomal transport [GO:0007041]; membrane organization [GO:0061024]; neutrophil degranulation [GO:0043312]; positive regulation by host of viral process [GO:0044794]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; receptor-mediated endocytosis [GO:0006898]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]	lysosomal transport [GO:0007041]	cell surface [GO:0009986]; clathrin coat [GO:0030118]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; trans-Golgi network transport vesicle [GO:0030140]; transport vesicle [GO:0030133]	integral component of membrane [GO:0016021]	enzyme binding [GO:0019899]; G-protein alpha-subunit binding [GO:0001965]; identical protein binding [GO:0042802]; insulin-like growth factor-activated receptor activity [GO:0005010]; insulin-like growth factor binding [GO:0005520]; insulin-like growth factor II binding [GO:0031995]; mannose binding [GO:0005537]; phosphoprotein binding [GO:0051219]; retinoic acid binding [GO:0001972]; signaling receptor activity [GO:0038023]	insulin-like growth factor binding [GO:0005520]; mannose binding [GO:0005537]; signaling receptor activity [GO:0038023]
d2l2ba__d1y2xc___1	Metazoa	Fungi	Cnidaria	Basidiomycota	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]	carbohydrate binding [GO:0030246]	cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]		channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]
d2l2ia1_d1u5gc___1	Metazoa	Metazoa	Chordata	Chordata	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter sequence-specific DNA binding [GO:0000987]; transcription regulatory region DNA binding [GO:0044212]; cellular response to peptide [GO:1901653]; erythrocyte differentiation [GO:0030218]; maternal process involved in female pregnancy [GO:0060135]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; B cell activation [GO:0042113]; negative regulation of cell population proliferation [GO:0008285]	cellular response to peptide [GO:1901653]; erythrocyte differentiation [GO:0030218]; maternal process involved in female pregnancy [GO:0060135]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]	B cell activation [GO:0042113]; negative regulation of cell population proliferation [GO:0008285]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter sequence-specific DNA binding [GO:0000987]; transcription regulatory region DNA binding [GO:0044212]	
d2l3ca__d1t4lb1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251]; adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; brain development [GO:0007420]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; positive regulation of mRNA processing [GO:0050685]; positive regulation of viral genome replication [GO:0045070]; regulation of cell cycle [GO:0051726]; RNA processing [GO:0006396]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; double-stranded RNA binding [GO:0003725]; ribonuclease III activity [GO:0004525]; box C/D snoRNA processing [GO:0034963]; box H/ACA snoRNA processing [GO:0034964]; chromatin organization [GO:0006325]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; pre-miRNA processing [GO:0031054]; primary miRNA processing [GO:0031053]; production of siRNA involved in RNA interference [GO:0030422]; regulation of fungal-type cell wall organization [GO:0060237]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; rRNA transcription [GO:0009303]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; brain development [GO:0007420]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; positive regulation of mRNA processing [GO:0050685]; positive regulation of viral genome replication [GO:0045070]; regulation of cell cycle [GO:0051726]; RNA processing [GO:0006396]	box C/D snoRNA processing [GO:0034963]; box H/ACA snoRNA processing [GO:0034964]; chromatin organization [GO:0006325]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; pre-miRNA processing [GO:0031054]; primary miRNA processing [GO:0031053]; production of siRNA involved in RNA interference [GO:0030422]; regulation of fungal-type cell wall organization [GO:0060237]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; rRNA transcription [GO:0009303]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251]	double-stranded RNA binding [GO:0003725]; ribonuclease III activity [GO:0004525]
d2l3ga1_d4q57b1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein kinase binding [GO:0019901]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; G protein-coupled receptor signaling pathway [GO:0007186]; Golgi organization [GO:0007030]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell cortex [GO:0005938]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	guanyl-nucleotide exchange factor activity [GO:0005085]; protein kinase binding [GO:0019901]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d2l3ma1_d2ropa2__1		Metazoa	Firmicutes	Chordata	copper ion binding [GO:0005507]; copper ion transport [GO:0006825]	cell [GO:0005623]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; protein maturation by copper ion transfer [GO:0015680]; response to copper ion [GO:0046688]; sequestering of calcium ion [GO:0051208]	copper ion transport [GO:0006825]	cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; protein maturation by copper ion transfer [GO:0015680]; response to copper ion [GO:0046688]; sequestering of calcium ion [GO:0051208]		cell [GO:0005623]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]	copper ion binding [GO:0005507]	ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]
d2l4ba1_d2kosa___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]	cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acyl carrier activity [GO:0000036]	acyl carrier activity [GO:0000036]
d2l4ba1_d4h2wc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]			cytoplasm [GO:0005737]		acyl carrier activity [GO:0000036]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]
d2l4qa__d3tkqc___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; S-nitrosoglutathione reductase activity [GO:0080007]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; S-nitrosoglutathione reductase activity [GO:0080007]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d2l4ra__d5svvb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; inward rectifier potassium channel complex [GO:1902937]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]; C3HC4-type RING finger domain binding [GO:0055131]; delayed rectifier potassium channel activity [GO:0005251]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]; voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1902282]; cardiac conduction [GO:0061337]; cardiac muscle contraction [GO:0060048]; cellular response to drug [GO:0035690]; membrane depolarization during action potential [GO:0086010]; membrane repolarization [GO:0086009]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; membrane repolarization during ventricular cardiac muscle cell action potential [GO:0098915]; negative regulation of potassium ion export across plasma membrane [GO:1903765]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion export across plasma membrane [GO:0097623]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of heart rate by hormone [GO:0003064]; regulation of membrane potential [GO:0042391]; regulation of membrane repolarization [GO:0060306]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; ventricular cardiac muscle cell action potential [GO:0086005]	cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; photoreceptor activity [GO:0009881]; circadian rhythm [GO:0007623]; flower development [GO:0009908]; protein ubiquitination [GO:0016567]; protein-chromophore linkage [GO:0018298]; response to blue light [GO:0009637]	cardiac conduction [GO:0061337]; cardiac muscle contraction [GO:0060048]; cellular response to drug [GO:0035690]; membrane depolarization during action potential [GO:0086010]; membrane repolarization [GO:0086009]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; membrane repolarization during ventricular cardiac muscle cell action potential [GO:0098915]; negative regulation of potassium ion export across plasma membrane [GO:1903765]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion export across plasma membrane [GO:0097623]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of heart rate by hormone [GO:0003064]; regulation of membrane potential [GO:0042391]; regulation of membrane repolarization [GO:0060306]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; ventricular cardiac muscle cell action potential [GO:0086005]	circadian rhythm [GO:0007623]; flower development [GO:0009908]; protein-chromophore linkage [GO:0018298]; protein ubiquitination [GO:0016567]; response to blue light [GO:0009637]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; inward rectifier potassium channel complex [GO:1902937]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]	cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	C3HC4-type RING finger domain binding [GO:0055131]; delayed rectifier potassium channel activity [GO:0005251]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]; voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1902282]	photoreceptor activity [GO:0009881]
d2l4xa__d1su0b___1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]; iron-sulfur cluster assembly [GO:0016226]	cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]	iron-sulfur cluster assembly [GO:0016226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]
d2l51a__d4orab___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; response to calcium ion [GO:0051592]	calcineurin complex [GO:0005955]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcolemma [GO:0042383]; calcium ion binding [GO:0005509]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; cyclosporin A binding [GO:0016018]; phosphatase binding [GO:0019902]; protein domain specific binding [GO:0019904]; calcineurin-NFAT signaling cascade [GO:0033173]; Fc-epsilon receptor signaling pathway [GO:0038095]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	response to calcium ion [GO:0051592]	calcineurin-NFAT signaling cascade [GO:0033173]; Fc-epsilon receptor signaling pathway [GO:0038095]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	calcineurin complex [GO:0005955]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcolemma [GO:0042383]	calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]	calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; cyclosporin A binding [GO:0016018]; phosphatase binding [GO:0019902]; protein domain specific binding [GO:0019904]
d2l54a__d1qgpa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; supraspliceosomal complex [GO:0044530]; DNA binding [GO:0003677]; double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251]; adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; RNA processing [GO:0006396]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; type I interferon signaling pathway [GO:0060337]	cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; supraspliceosomal complex [GO:0044530]; DNA binding [GO:0003677]; double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251]; adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; RNA processing [GO:0006396]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; type I interferon signaling pathway [GO:0060337]	adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; RNA processing [GO:0006396]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; type I interferon signaling pathway [GO:0060337]	adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; RNA processing [GO:0006396]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; type I interferon signaling pathway [GO:0060337]	cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; supraspliceosomal complex [GO:0044530]	cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; supraspliceosomal complex [GO:0044530]	DNA binding [GO:0003677]; double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251]	DNA binding [GO:0003677]; double-stranded RNA adenosine deaminase activity [GO:0003726]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; tRNA-specific adenosine deaminase activity [GO:0008251]
d2l59a__d2pbjd2__1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; S-nitrosoglutathione reductase activity [GO:0080007]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]	disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; S-nitrosoglutathione reductase activity [GO:0080007]	electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]
d2l5la1_d3ztlg___1		Metazoa	Bacteroidetes	Platyhelminthes	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	protein disulfide oxidoreductase activity [GO:0015035]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2l5ta__d1k8ma1__1		Metazoa	Euryarchaeota	Chordata	identical protein binding [GO:0042802]; transferase activity, transferring acyl groups [GO:0016746]	cytoplasm [GO:0005737]; mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]; branched-chain amino acid catabolic process [GO:0009083]		branched-chain amino acid catabolic process [GO:0009083]		cytoplasm [GO:0005737]; mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; transferase activity, transferring acyl groups [GO:0016746]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d2l5xa__d3baqb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2l5xd__d4qc4b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2l6ea1_d3g26a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]; aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral procapsid maturation [GO:0046797]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral procapsid maturation [GO:0046797]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d2l74a__d3kyga2__1			Proteobacteria	Proteobacteria	cyclic-di-GMP binding [GO:0035438]; second-messenger-mediated signaling [GO:0019932]	bacterial-type flagellum basal body [GO:0009425]; cofactor binding [GO:0048037]; cyclic-di-GMP binding [GO:0035438]	second-messenger-mediated signaling [GO:0019932]			bacterial-type flagellum basal body [GO:0009425]	cyclic-di-GMP binding [GO:0035438]	cofactor binding [GO:0048037]; cyclic-di-GMP binding [GO:0035438]
d2l7ra__d2faza1__1	Metazoa	Metazoa	Chordata	Chordata	RNA binding [GO:0003723]	euchromatin [GO:0000791]; heterochromatin [GO:0000792]; nuclear chromatin [GO:0000790]; nuclear heterochromatin [GO:0005720]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; replication fork [GO:0005657]; hemi-methylated DNA-binding [GO:0044729]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methyl-CpG binding [GO:0008327]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; proximal promoter sequence-specific DNA binding [GO:0000987]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; cell cycle [GO:0007049]; DNA repair [GO:0006281]; histone monoubiquitination [GO:0010390]; histone ubiquitination [GO:0016574]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of epithelial cell proliferation [GO:0050678]; ubiquitin-dependent protein catabolic process [GO:0006511]		cell cycle [GO:0007049]; DNA repair [GO:0006281]; histone monoubiquitination [GO:0010390]; histone ubiquitination [GO:0016574]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of epithelial cell proliferation [GO:0050678]; ubiquitin-dependent protein catabolic process [GO:0006511]		euchromatin [GO:0000791]; heterochromatin [GO:0000792]; nuclear chromatin [GO:0000790]; nuclear heterochromatin [GO:0005720]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; replication fork [GO:0005657]	RNA binding [GO:0003723]	hemi-methylated DNA-binding [GO:0044729]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; methyl-CpG binding [GO:0008327]; nucleosomal histone binding [GO:0031493]; proximal promoter sequence-specific DNA binding [GO:0000987]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d2l84a1_d5lvqa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]
d2l85a1_d5lpkg___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]; acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]
d2l8aa1_d2xbda___1			Firmicutes	Actinobacteria	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]
d2l8ja1_d5dpwi___1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cell body [GO:0044297]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendrite membrane [GO:0032590]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; intracellular [GO:0005622]; microtubule [GO:0005874]; beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; Tat protein binding [GO:0030957]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]	endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; nucleolus [GO:0005730]; metal ion binding [GO:0046872]; autophagy [GO:0006914]; intracellular signal transduction [GO:0035556]; lysosome localization [GO:0032418]; positive regulation of bone resorption [GO:0045780]; positive regulation of ruffle assembly [GO:1900029]; protein transport [GO:0015031]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]	autophagy [GO:0006914]; intracellular signal transduction [GO:0035556]; lysosome localization [GO:0032418]; positive regulation of bone resorption [GO:0045780]; positive regulation of ruffle assembly [GO:1900029]; protein transport [GO:0015031]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cell body [GO:0044297]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendrite membrane [GO:0032590]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; intracellular [GO:0005622]; microtubule [GO:0005874]	endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; nucleolus [GO:0005730]	beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; Tat protein binding [GO:0030957]; ubiquitin protein ligase binding [GO:0031625]	metal ion binding [GO:0046872]
d2l8ma__d4bf4b___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2l9hb__d1dona___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR1 chemokine receptor binding [GO:0031726]; CCR4 chemokine receptor binding [GO:0031729]; CCR5 chemokine receptor binding [GO:0031730]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; chemokine receptor antagonist activity [GO:0046817]; chemokine receptor binding [GO:0042379]; identical protein binding [GO:0042802]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase activator activity [GO:0016004]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein self-association [GO:0043621]; receptor signaling protein tyrosine kinase activator activity [GO:0030298]; activation of phospholipase D activity [GO:0031584]; calcium ion transport [GO:0006816]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell chemotaxis [GO:0002407]; eosinophil chemotaxis [GO:0048245]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of viral genome replication [GO:0045071]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cellular biosynthetic process [GO:0031328]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of innate immune response [GO:0045089]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphorylation [GO:0042327]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell apoptotic process [GO:0070234]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of T cell migration [GO:2000406]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of translational initiation [GO:0045948]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of viral genome replication [GO:0045070]; protein kinase B signaling [GO:0043491]; regulation of chronic inflammatory response [GO:0002676]; regulation of insulin secretion [GO:0050796]; regulation of neuron death [GO:1901214]; regulation of T cell activation [GO:0050863]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR2 chemokine receptor binding [GO:0031727]; chemokine activity [GO:0008009]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; astrocyte cell migration [GO:0043615]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular homeostasis [GO:0019725]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; helper T cell extravasation [GO:0035684]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of natural killer cell chemotaxis [GO:2000502]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of calcium ion import [GO:0090280]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of T cell activation [GO:0050870]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; viral genome replication [GO:0019079]	activation of phospholipase D activity [GO:0031584]; calcium ion transport [GO:0006816]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell chemotaxis [GO:0002407]; eosinophil chemotaxis [GO:0048245]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of viral genome replication [GO:0045071]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular biosynthetic process [GO:0031328]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of innate immune response [GO:0045089]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphorylation [GO:0042327]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell apoptotic process [GO:0070234]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of T cell migration [GO:2000406]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of translational initiation [GO:0045948]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of viral genome replication [GO:0045070]; protein kinase B signaling [GO:0043491]; regulation of chronic inflammatory response [GO:0002676]; regulation of insulin secretion [GO:0050796]; regulation of neuron death [GO:1901214]; regulation of T cell activation [GO:0050863]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; astrocyte cell migration [GO:0043615]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular homeostasis [GO:0019725]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; helper T cell extravasation [GO:0035684]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of natural killer cell chemotaxis [GO:2000502]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of calcium ion import [GO:0090280]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of T cell activation [GO:0050870]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; viral genome replication [GO:0019079]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	CCR1 chemokine receptor binding [GO:0031726]; CCR4 chemokine receptor binding [GO:0031729]; CCR5 chemokine receptor binding [GO:0031730]; CCR chemokine receptor binding [GO:0048020]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; chemokine receptor antagonist activity [GO:0046817]; chemokine receptor binding [GO:0042379]; identical protein binding [GO:0042802]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase activator activity [GO:0016004]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein self-association [GO:0043621]; receptor signaling protein tyrosine kinase activator activity [GO:0030298]	CCR2 chemokine receptor binding [GO:0031727]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]
d2l9la1_d1f4ad3__1	Metazoa		Chordata	Proteobacteria	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integrin binding [GO:0005178]; phosphatidylethanolamine binding [GO:0008429]; phosphatidylserine binding [GO:0001786]; angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; single fertilization [GO:0007338]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	angiogenesis [GO:0001525]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; single fertilization [GO:0007338]	lactose catabolic process [GO:0005990]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]	beta-galactosidase complex [GO:0009341]	integrin binding [GO:0005178]; phosphatidylethanolamine binding [GO:0008429]; phosphatidylserine binding [GO:0001786]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2lal.1_d5duua___1	Viridiplantae	Metazoa	Streptophyta	Chordata	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]; carbohydrate mediated signaling [GO:0009756]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]	carbohydrate mediated signaling [GO:0009756]	cell adhesion [GO:0007155]		collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2laoa__d4xwsa___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; amino acid transport [GO:0006865]	protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of secondary metabolite biosynthetic process [GO:1900377]; positive regulation of cell motility [GO:2000147]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of superoxide dismutase activity [GO:1901671]; regulation of response to reactive oxygen species [GO:1901031]; regulation of transcription, DNA-templated [GO:0006355]	amino acid transport [GO:0006865]	negative regulation of secondary metabolite biosynthetic process [GO:1900377]; positive regulation of cell motility [GO:2000147]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of superoxide dismutase activity [GO:1901671]; regulation of response to reactive oxygen species [GO:1901031]; regulation of transcription, DNA-templated [GO:0006355]	outer membrane-bounded periplasmic space [GO:0030288]	protein-DNA complex [GO:0032993]		DNA-binding transcription activator activity [GO:0001216]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2lb5a1_d3s7pa2__1			Cyanobacteria	Deinococcus-Thermus	phosphorelay sensor kinase activity [GO:0000155]; detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			phosphorelay sensor kinase activity [GO:0000155]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d2lb5a1_d3zq5a3__1			Cyanobacteria	Cyanobacteria	phosphorelay sensor kinase activity [GO:0000155]; detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; red or far-red light photoreceptor activity [GO:0009883]; detection of visible light [GO:0009584]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; red, far-red light phototransduction [GO:0009585]; regulation of transcription, DNA-templated [GO:0006355]; response to red or far red light [GO:0009639]	detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; red, far-red light phototransduction [GO:0009585]; regulation of transcription, DNA-templated [GO:0006355]; response to red or far red light [GO:0009639]			phosphorelay sensor kinase activity [GO:0000155]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; red or far-red light photoreceptor activity [GO:0009883]
d2lbha__d2hnue___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; secretory granule [GO:0030141]; neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	extracellular space [GO:0005615]; secretory granule [GO:0030141]; neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	positive regulation of cold-induced thermogenesis [GO:0120162]; response to estrogen [GO:0043627]; response to external biotic stimulus [GO:0043207]; response to food [GO:0032094]; response to mechanical stimulus [GO:0009612]	extracellular space [GO:0005615]; secretory granule [GO:0030141]	extracellular space [GO:0005615]; secretory granule [GO:0030141]	neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]	neurohypophyseal hormone activity [GO:0005185]; neuropeptide hormone activity [GO:0005184]; oxytocin receptor binding [GO:0031855]
d2lc5a__d5dbra___1		Metazoa		Chordata	calcium ion binding [GO:0005509]; calcium-mediated signaling [GO:0019722]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	calcium-mediated signaling [GO:0019722]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d2lc6a1_d2uzce___1	Metazoa	Metazoa	Arthropoda	Chordata	apical cortex [GO:0045179]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; muscle cell postsynaptic specialization [GO:0097482]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; subapical complex [GO:0035003]; terminal bouton [GO:0043195]; protein kinase C binding [GO:0005080]; Rho GTPase binding [GO:0017048]; apical protein localization [GO:0045176]; asymmetric neuroblast division [GO:0055059]; border follicle cell migration [GO:0007298]; branching involved in open tracheal system development [GO:0060446]; centrosome cycle [GO:0007098]; establishment of neuroblast polarity [GO:0045200]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; establishment or maintenance of neuroblast polarity [GO:0045196]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of lamellipodium assembly [GO:0010592]; regulation of cellular localization [GO:0060341]; synapse assembly [GO:0007416]; terminal branching, open tracheal system [GO:0007430]; zonula adherens assembly [GO:0045186]	actin cytoskeleton [GO:0015629]; cell projection [GO:0042995]; cell-cell adherens junction [GO:0005913]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; membrane [GO:0016020]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; actinin binding [GO:0042805]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase C binding [GO:0005080]; protein N-terminus binding [GO:0047485]; actin cytoskeleton organization [GO:0030036]; cell growth involved in cardiac muscle cell development [GO:0061049]; heart development [GO:0007507]; muscle structure development [GO:0061061]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of synapse assembly [GO:0051963]	apical protein localization [GO:0045176]; asymmetric neuroblast division [GO:0055059]; border follicle cell migration [GO:0007298]; branching involved in open tracheal system development [GO:0060446]; centrosome cycle [GO:0007098]; establishment of neuroblast polarity [GO:0045200]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; establishment or maintenance of neuroblast polarity [GO:0045196]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of lamellipodium assembly [GO:0010592]; regulation of cellular localization [GO:0060341]; synapse assembly [GO:0007416]; terminal branching, open tracheal system [GO:0007430]; zonula adherens assembly [GO:0045186]	actin cytoskeleton organization [GO:0030036]; cell growth involved in cardiac muscle cell development [GO:0061049]; heart development [GO:0007507]; muscle structure development [GO:0061061]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of synapse assembly [GO:0051963]	apical cortex [GO:0045179]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; muscle cell postsynaptic specialization [GO:0097482]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; subapical complex [GO:0035003]; terminal bouton [GO:0043195]	actin cytoskeleton [GO:0015629]; cell-cell adherens junction [GO:0005913]; cell projection [GO:0042995]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; membrane [GO:0016020]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; stress fiber [GO:0001725]; Z disc [GO:0030018]	protein kinase C binding [GO:0005080]; Rho GTPase binding [GO:0017048]	actin binding [GO:0003779]; actinin binding [GO:0042805]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase C binding [GO:0005080]; protein N-terminus binding [GO:0047485]
d2lcba__d1j8xc___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]		lysozyme activity [GO:0003796]	
d2lcpa__d2r2ia___1	Metazoa	Metazoa	Chordata	Chordata	calyx of Held [GO:0044305]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dense core granule [GO:0031045]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic cytosol [GO:0099523]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; protein kinase binding [GO:0019901]; voltage-gated calcium channel activity [GO:0005245]; voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels [GO:0099626]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of exocytosis [GO:0045921]; regulation of neuron projection development [GO:0010975]; regulation of synaptic vesicle exocytosis [GO:2000300]	photoreceptor outer segment [GO:0001750]; calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048]; guanylate cyclase regulator activity [GO:0030249]; cellular response to calcium ion [GO:0071277]; phototransduction [GO:0007602]; positive regulation of guanylate cyclase activity [GO:0031284]; visual perception [GO:0007601]	phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of exocytosis [GO:0045921]; regulation of neuron projection development [GO:0010975]; regulation of synaptic vesicle exocytosis [GO:2000300]	cellular response to calcium ion [GO:0071277]; phototransduction [GO:0007602]; positive regulation of guanylate cyclase activity [GO:0031284]; visual perception [GO:0007601]	calyx of Held [GO:0044305]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dense core granule [GO:0031045]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic cytosol [GO:0099523]	photoreceptor outer segment [GO:0001750]	calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; protein kinase binding [GO:0019901]; voltage-gated calcium channel activity [GO:0005245]; voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels [GO:0099626]	calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048]; guanylate cyclase regulator activity [GO:0030249]
d2ldia__d2kt2a___1			Cyanobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; cadmium ion transmembrane transporter activity [GO:0015086]; metal ion binding [GO:0046872]; zinc ion transmembrane transporter activity [GO:0005385]; zinc transmembrane transporter activity, phosphorylative mechanism [GO:0016463]	cell [GO:0005623]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; mercury (II) reductase activity [GO:0016152]; mercury ion binding [GO:0045340]; NADP binding [GO:0050661]; oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor [GO:0016668]; cell redox homeostasis [GO:0045454]; detoxification of mercury ion [GO:0050787]; metal ion transport [GO:0030001]		cell redox homeostasis [GO:0045454]; detoxification of mercury ion [GO:0050787]; metal ion transport [GO:0030001]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell [GO:0005623]	ATP binding [GO:0005524]; cadmium ion transmembrane transporter activity [GO:0015086]; metal ion binding [GO:0046872]; zinc ion transmembrane transporter activity [GO:0005385]; zinc transmembrane transporter activity, phosphorylative mechanism [GO:0016463]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; mercury (II) reductase activity [GO:0016152]; mercury ion binding [GO:0045340]; NADP binding [GO:0050661]; oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor [GO:0016668]
d2ldka1_d2hmoa2__1			Actinobacteria	Proteobacteria		dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]				dioxygenase activity [GO:0051213]
d2ldua1_d1fbqb1__1	Metazoa	Fungi	Chordata	Ascomycota	centrosome [GO:0005813]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; heterochromatin [GO:0000792]; kinetochore [GO:0000776]; mitotic spindle pole [GO:0097431]; nuclear chromatin [GO:0000790]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; PML body [GO:0016605]; pronucleus [GO:0045120]; ribonucleoprotein complex [GO:1990904]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; heat shock protein binding [GO:0031072]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific single stranded DNA binding [GO:0098847]; STAT family protein binding [GO:0097677]; translation elongation factor binding [GO:0061770]; cellular protein-containing complex assembly [GO:0034622]; cellular response to angiotensin [GO:1904385]; cellular response to cadmium ion [GO:0071276]; cellular response to copper ion [GO:0071280]; cellular response to diamide [GO:0072738]; cellular response to estradiol stimulus [GO:0071392]; cellular response to gamma radiation [GO:0071480]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to L-glutamine [GO:1904845]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nitroglycerin [GO:1904843]; cellular response to potassium ion [GO:0035865]; cellular response to sodium arsenite [GO:1903936]; cellular response to unfolded protein [GO:0034620]; defense response [GO:0006952]; DNA repair [GO:0006281]; embryonic placenta development [GO:0001892]; embryonic process involved in female pregnancy [GO:0060136]; female meiotic nuclear division [GO:0007143]; MAPK cascade [GO:0000165]; mRNA processing [GO:0006397]; mRNA transcription [GO:0009299]; mRNA transport [GO:0051028]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of double-strand break repair via nonhomologous end joining [GO:2001033]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of neuron death [GO:1901215]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inclusion body assembly [GO:0090261]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mRNA polyadenylation [GO:1900365]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to heat stress [GO:0061408]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; regulation of cellular response to heat [GO:1900034]; regulation of protein heterodimerization activity [GO:0043497]; response to activity [GO:0014823]; response to hypobaric hypoxia [GO:1990910]; response to psychosocial stress [GO:1990911]; response to testosterone [GO:0033574]; spermatogenesis [GO:0007283]	nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	cellular protein-containing complex assembly [GO:0034622]; cellular response to angiotensin [GO:1904385]; cellular response to cadmium ion [GO:0071276]; cellular response to copper ion [GO:0071280]; cellular response to diamide [GO:0072738]; cellular response to estradiol stimulus [GO:0071392]; cellular response to gamma radiation [GO:0071480]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to L-glutamine [GO:1904845]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nitroglycerin [GO:1904843]; cellular response to potassium ion [GO:0035865]; cellular response to sodium arsenite [GO:1903936]; cellular response to unfolded protein [GO:0034620]; defense response [GO:0006952]; DNA repair [GO:0006281]; embryonic placenta development [GO:0001892]; embryonic process involved in female pregnancy [GO:0060136]; female meiotic nuclear division [GO:0007143]; MAPK cascade [GO:0000165]; mRNA processing [GO:0006397]; mRNA transcription [GO:0009299]; mRNA transport [GO:0051028]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of double-strand break repair via nonhomologous end joining [GO:2001033]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of neuron death [GO:1901215]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inclusion body assembly [GO:0090261]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mRNA polyadenylation [GO:1900365]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to heat stress [GO:0061408]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; regulation of cellular response to heat [GO:1900034]; regulation of protein heterodimerization activity [GO:0043497]; response to activity [GO:0014823]; response to hypobaric hypoxia [GO:1990910]; response to psychosocial stress [GO:1990911]; response to testosterone [GO:0033574]; spermatogenesis [GO:0007283]		centrosome [GO:0005813]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; heterochromatin [GO:0000792]; kinetochore [GO:0000776]; mitotic spindle pole [GO:0097431]; nuclear chromatin [GO:0000790]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; PML body [GO:0016605]; pronucleus [GO:0045120]; ribonucleoprotein complex [GO:1990904]	nucleus [GO:0005634]; protein-DNA complex [GO:0032993]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; heat shock protein binding [GO:0031072]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; sequence-specific single stranded DNA binding [GO:0098847]; STAT family protein binding [GO:0097677]; translation elongation factor binding [GO:0061770]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]
d2ldxb1_d1omob___1	Metazoa		Chordata	Euryarchaeota	cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]; L-lactate dehydrogenase activity [GO:0004459]; ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]	alanine dehydrogenase activity [GO:0000286]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]; alanine metabolic process [GO:0006522]	ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]	alanine metabolic process [GO:0006522]	cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]		L-lactate dehydrogenase activity [GO:0004459]	alanine dehydrogenase activity [GO:0000286]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]
d2ldxb2_d2hjrc2__1	Metazoa		Chordata	Apicomplexa	cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]; L-lactate dehydrogenase activity [GO:0004459]; ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]		L-lactate dehydrogenase activity [GO:0004459]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d2ldxb2_d3vkvc2__1	Metazoa		Chordata		cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]; L-lactate dehydrogenase activity [GO:0004459]; ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]		ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]		cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]		L-lactate dehydrogenase activity [GO:0004459]	
d2ldxc1_d4l4sh1__1	Metazoa	Metazoa	Chordata	Chordata	cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]; L-lactate dehydrogenase activity [GO:0004459]; ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-lactate dehydrogenase activity [GO:0004459]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2le4a1_d1cg7a___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; miRNA binding [GO:0035198]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; adenohypophysis development [GO:0021984]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell fate specification [GO:0001714]; eye development [GO:0001654]; forebrain development [GO:0030900]; glial cell fate commitment [GO:0021781]; inner ear development [GO:0048839]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuronal stem cell population maintenance [GO:0097150]; osteoblast differentiation [GO:0001649]; pituitary gland development [GO:0021983]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; response to growth factor [GO:0070848]; response to wounding [GO:0009611]; somatic stem cell population maintenance [GO:0035019]; tissue regeneration [GO:0042246]	nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; DNA binding, bending [GO:0008301]; MutSalpha complex binding [GO:0032407]; nucleosome binding [GO:0031491]; chromatin remodeling [GO:0006338]; DNA replication-independent nucleosome organization [GO:0034724]; maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter [GO:0001195]; mismatch repair [GO:0006298]; negative regulation of DNA binding [GO:0043392]; protein-DNA complex assembly [GO:0065004]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]	adenohypophysis development [GO:0021984]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell fate specification [GO:0001714]; eye development [GO:0001654]; forebrain development [GO:0030900]; glial cell fate commitment [GO:0021781]; inner ear development [GO:0048839]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuronal stem cell population maintenance [GO:0097150]; osteoblast differentiation [GO:0001649]; pituitary gland development [GO:0021983]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell differentiation [GO:0045597]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; response to growth factor [GO:0070848]; response to wounding [GO:0009611]; somatic stem cell population maintenance [GO:0035019]; tissue regeneration [GO:0042246]	chromatin remodeling [GO:0006338]; DNA replication-independent nucleosome organization [GO:0034724]; maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter [GO:0001195]; mismatch repair [GO:0006298]; negative regulation of DNA binding [GO:0043392]; protein-DNA complex assembly [GO:0065004]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; miRNA binding [GO:0035198]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding, bending [GO:0008301]; MutSalpha complex binding [GO:0032407]; nucleosome binding [GO:0031491]
d2le4a1_d2e6oa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; miRNA binding [GO:0035198]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; adenohypophysis development [GO:0021984]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell fate specification [GO:0001714]; eye development [GO:0001654]; forebrain development [GO:0030900]; glial cell fate commitment [GO:0021781]; inner ear development [GO:0048839]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuronal stem cell population maintenance [GO:0097150]; osteoblast differentiation [GO:0001649]; pituitary gland development [GO:0021983]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; response to growth factor [GO:0070848]; response to wounding [GO:0009611]; somatic stem cell population maintenance [GO:0035019]; tissue regeneration [GO:0042246]	nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA binding [GO:0003723]; cell cycle arrest [GO:0007050]; Wnt signaling pathway [GO:0016055]	adenohypophysis development [GO:0021984]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell fate specification [GO:0001714]; eye development [GO:0001654]; forebrain development [GO:0030900]; glial cell fate commitment [GO:0021781]; inner ear development [GO:0048839]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuronal stem cell population maintenance [GO:0097150]; osteoblast differentiation [GO:0001649]; pituitary gland development [GO:0021983]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell differentiation [GO:0045597]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; response to growth factor [GO:0070848]; response to wounding [GO:0009611]; somatic stem cell population maintenance [GO:0035019]; tissue regeneration [GO:0042246]	cell cycle arrest [GO:0007050]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; miRNA binding [GO:0035198]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA binding [GO:0003723]
d2le9b__d3nslc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]	cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]
d2lena1_d1xd3c___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; adult walking behavior [GO:0007628]; axon target recognition [GO:0007412]; axonal transport of mitochondrion [GO:0019896]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	adult walking behavior [GO:0007628]; axonal transport of mitochondrion [GO:0019896]; axon target recognition [GO:0007412]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2lhma__d4xena___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2lhma__d5d5aa2__1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2liga__d2d4ub___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; transmembrane signaling receptor activity [GO:0004888]; chemotaxis [GO:0006935]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]; protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cell motility [GO:0048870]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; protein homooligomerization [GO:0051260]; receptor clustering [GO:0043113]; regulation of bacterial-type flagellum-dependent cell motility [GO:1902021]; regulation of chemotaxis [GO:0050920]; regulation of protein histidine kinase activity [GO:0032110]; response to amino acid [GO:0043200]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	cell motility [GO:0048870]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; protein homooligomerization [GO:0051260]; receptor clustering [GO:0043113]; regulation of bacterial-type flagellum-dependent cell motility [GO:1902021]; regulation of chemotaxis [GO:0050920]; regulation of protein histidine kinase activity [GO:0032110]; response to amino acid [GO:0043200]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]	transmembrane signaling receptor activity [GO:0004888]	protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]
d2ligb__d4z9jb___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; transmembrane signaling receptor activity [GO:0004888]; chemotaxis [GO:0006935]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; positive regulation of post-translational protein modification [GO:1901875]; protein homooligomerization [GO:0051260]; regulation of chemotaxis [GO:0050920]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; positive regulation of post-translational protein modification [GO:1901875]; protein homooligomerization [GO:0051260]; regulation of chemotaxis [GO:0050920]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]	transmembrane signaling receptor activity [GO:0004888]	protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]
d2lipa__d2dqza___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	lipid catabolic process [GO:0016042]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	extracellular region [GO:0005576]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d2lira__d3zoxb___1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2liva__d3hs3b1__1			Proteobacteria	Firmicutes	outer membrane-bounded periplasmic space [GO:0030288]; isoleucine transport [GO:0015818]; leucine transport [GO:0015820]; valine transport [GO:0015829]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	isoleucine transport [GO:0015818]; leucine transport [GO:0015820]; valine transport [GO:0015829]	regulation of transcription, DNA-templated [GO:0006355]	outer membrane-bounded periplasmic space [GO:0030288]			DNA binding [GO:0003677]
d2lj8a__d1jhwa3__1		Metazoa		Chordata	actin cytoskeleton [GO:0015629]; ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nuclear lumen [GO:0031981]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]; cell division [GO:0051301]; centriole replication [GO:0007099]; intracellular transport [GO:0046907]	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	actin filament depolymerization [GO:0030042]; cell division [GO:0051301]; centriole replication [GO:0007099]; intracellular transport [GO:0046907]	barbed-end actin filament capping [GO:0051016]; protein-containing complex assembly [GO:0065003]	actin cytoskeleton [GO:0015629]; ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nuclear lumen [GO:0031981]	centriole [GO:0005814]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; F-actin capping protein complex [GO:0008290]; Flemming body [GO:0090543]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; mitotic spindle [GO:0072686]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	actin binding [GO:0003779]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]
d2ljoa__d1fk5a___1		Viridiplantae		Streptophyta		lipid binding [GO:0008289]; lipid transport [GO:0006869]		lipid transport [GO:0006869]				lipid binding [GO:0008289]
d2ljrb1_d4i97a2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	transferase activity [GO:0016740]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d2lkka__d1yp7a___1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone activity [GO:0005186]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to food [GO:0071240]; cellular response to lipid [GO:0071396]; cellular response to starvation [GO:0009267]; cellular response to testosterone stimulus [GO:0071394]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]; response to stilbenoid [GO:0035634]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	aerobic respiration [GO:0009060]; cellular response to food [GO:0071240]; cellular response to lipid [GO:0071396]; cellular response to starvation [GO:0009267]; cellular response to testosterone stimulus [GO:0071394]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]; response to stilbenoid [GO:0035634]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]	insulin-activated receptor activity [GO:0005009]; pheromone activity [GO:0005186]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]
d2lkpb__d1hstb___1		Metazoa	Actinobacteria	Chordata	DNA-binding transcription factor activity [GO:0003700]	nucleosome [GO:0000786]; nucleus [GO:0005634]; double-stranded DNA binding [GO:0003690]; nucleosomal DNA binding [GO:0031492]; chromatin organization [GO:0006325]; chromosome condensation [GO:0030261]; negative regulation of chromatin silencing [GO:0031936]; negative regulation of DNA recombination [GO:0045910]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; regulation of transcription, DNA-templated [GO:0006355]		chromatin organization [GO:0006325]; chromosome condensation [GO:0030261]; negative regulation of chromatin silencing [GO:0031936]; negative regulation of DNA recombination [GO:0045910]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; regulation of transcription, DNA-templated [GO:0006355]		nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA-binding transcription factor activity [GO:0003700]	double-stranded DNA binding [GO:0003690]; nucleosomal DNA binding [GO:0031492]
d2lkva__d2f3va___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2llna__d3x2qo2__1		Metazoa	Deinococcus-Thermus	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]		ATP synthesis coupled electron transport [GO:0042773]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2lm3a1_d5nbpb___1	Metazoa		Chordata	Bacteroidetes	cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]; identical protein binding [GO:0042802]; signaling pattern recognition receptor activity [GO:0008329]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipopolysaccharide-mediated signaling pathway [GO:0031664]; regulation of protein localization [GO:0032880]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipopolysaccharide-mediated signaling pathway [GO:0031664]; regulation of protein localization [GO:0032880]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]		identical protein binding [GO:0042802]; signaling pattern recognition receptor activity [GO:0008329]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2lmda1_d1akhb___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; LBD domain binding [GO:0050693]; nuclear receptor binding [GO:0016922]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription regulatory region DNA binding [GO:0044212]; acinar cell differentiation [GO:0090425]; aorta smooth muscle tissue morphogenesis [GO:0060414]; atrial cardiac muscle tissue morphogenesis [GO:0055009]; brain development [GO:0007420]; branching involved in pancreas morphogenesis [GO:0061114]; cell fate determination [GO:0001709]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; dentate gyrus development [GO:0021542]; dorsal spinal cord development [GO:0021516]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; endocardium formation [GO:0060214]; hepatocyte cell migration [GO:0002194]; hepatocyte differentiation [GO:0070365]; hepatocyte proliferation [GO:0072574]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; lens fiber cell morphogenesis [GO:0070309]; liver development [GO:0001889]; lung development [GO:0030324]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell differentiation [GO:0060836]; negative regulation of bile acid biosynthetic process [GO:0070858]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; olfactory placode formation [GO:0030910]; optic placode formation involved in camera-type eye formation [GO:0046619]; otic placode formation [GO:0043049]; pancreas development [GO:0031016]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell cycle checkpoint [GO:1901978]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of forebrain neuron differentiation [GO:2000979]; positive regulation of heart growth [GO:0060421]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of sarcomere organization [GO:0060298]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of gene expression [GO:0010468]; regulation of transcription involved in lymphatic endothelial cell fate commitment [GO:0060849]; response to nutrient levels [GO:0031667]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle thin filament assembly [GO:0030240]; venous blood vessel morphogenesis [GO:0048845]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular cardiac myofibril assembly [GO:0055005]; ventricular septum morphogenesis [GO:0060412]	nucleus [GO:0005634]; sequence-specific DNA binding [GO:0043565]; regulation of transcription, DNA-templated [GO:0006355]	acinar cell differentiation [GO:0090425]; aorta smooth muscle tissue morphogenesis [GO:0060414]; atrial cardiac muscle tissue morphogenesis [GO:0055009]; brain development [GO:0007420]; branching involved in pancreas morphogenesis [GO:0061114]; cell fate determination [GO:0001709]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; dentate gyrus development [GO:0021542]; dorsal spinal cord development [GO:0021516]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; endocardium formation [GO:0060214]; hepatocyte cell migration [GO:0002194]; hepatocyte differentiation [GO:0070365]; hepatocyte proliferation [GO:0072574]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; lens fiber cell morphogenesis [GO:0070309]; liver development [GO:0001889]; lung development [GO:0030324]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell differentiation [GO:0060836]; negative regulation of bile acid biosynthetic process [GO:0070858]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; olfactory placode formation [GO:0030910]; optic placode formation involved in camera-type eye formation [GO:0046619]; otic placode formation [GO:0043049]; pancreas development [GO:0031016]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell cycle checkpoint [GO:1901978]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of forebrain neuron differentiation [GO:2000979]; positive regulation of heart growth [GO:0060421]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of sarcomere organization [GO:0060298]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; regulation of gene expression [GO:0010468]; regulation of transcription involved in lymphatic endothelial cell fate commitment [GO:0060849]; response to nutrient levels [GO:0031667]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle thin filament assembly [GO:0030240]; venous blood vessel morphogenesis [GO:0048845]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular cardiac myofibril assembly [GO:0055005]; ventricular septum morphogenesis [GO:0060412]	regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	nucleus [GO:0005634]	DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; LBD domain binding [GO:0050693]; nuclear receptor binding [GO:0016922]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription regulatory region DNA binding [GO:0044212]	sequence-specific DNA binding [GO:0043565]
d2lmia1_d4a8xa1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; ribonucleoprotein granule [GO:0035770]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; anterior/posterior pattern specification [GO:0009952]; morphogenesis of embryonic epithelium [GO:0016331]; mRNA polyadenylation [GO:0006378]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; tRNA processing [GO:0008033]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]; nucleic acid binding [GO:0003676]; apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transposition, DNA-mediated [GO:0000335]; regulation of autophagy [GO:0010506]; RNA splicing [GO:0008380]	anterior/posterior pattern specification [GO:0009952]; morphogenesis of embryonic epithelium [GO:0016331]; mRNA polyadenylation [GO:0006378]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; tRNA processing [GO:0008033]	apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transposition, DNA-mediated [GO:0000335]; regulation of autophagy [GO:0010506]; RNA splicing [GO:0008380]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; ribonucleoprotein granule [GO:0035770]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	nucleic acid binding [GO:0003676]
d2lmua__d2le9c___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; investment cone [GO:0070865]; myosin VI complex [GO:0031476]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; myosin VI head/neck binding [GO:0070855]; actin filament-based movement [GO:0030048]; calcium-mediated signaling [GO:0019722]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	actin filament-based movement [GO:0030048]; calcium-mediated signaling [GO:0019722]	cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	cytoplasm [GO:0005737]; investment cone [GO:0070865]; myosin VI complex [GO:0031476]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; myosin VI head/neck binding [GO:0070855]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d2lmva__d2zrsg___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; investment cone [GO:0070865]; myosin VI complex [GO:0031476]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; myosin VI head/neck binding [GO:0070855]; actin filament-based movement [GO:0030048]; calcium-mediated signaling [GO:0019722]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	actin filament-based movement [GO:0030048]; calcium-mediated signaling [GO:0019722]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	cytoplasm [GO:0005737]; investment cone [GO:0070865]; myosin VI complex [GO:0031476]; nucleus [GO:0005634]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; myosin VI head/neck binding [GO:0070855]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]
d2lnsb1_d1axdb2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; dystroglycan binding [GO:0002162]; epidermal growth factor receptor binding [GO:0005154]; protein homodimerization activity [GO:0042803]; digestive tract morphogenesis [GO:0048546]; lung goblet cell differentiation [GO:0060480]; mucus secretion [GO:0070254]; negative regulation of cell death [GO:0060548]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of developmental growth [GO:0048639]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of gene expression [GO:0010628]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; positive regulation of protein localization to plasma membrane [GO:1903078]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	digestive tract morphogenesis [GO:0048546]; lung goblet cell differentiation [GO:0060480]; mucus secretion [GO:0070254]; negative regulation of cell death [GO:0060548]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of developmental growth [GO:0048639]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of gene expression [GO:0010628]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; positive regulation of protein localization to plasma membrane [GO:1903078]	glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	dystroglycan binding [GO:0002162]; epidermal growth factor receptor binding [GO:0005154]; protein homodimerization activity [GO:0042803]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2lp2b__d1wlzb2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]	intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]		extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	nucleoplasm [GO:0005654]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]	calcium ion binding [GO:0005509]
d2lp2b__d4xjkj___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d2lp3a__d3fs7b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]	intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]		extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]	calcium ion binding [GO:0005509]
d2lp3b__d2h61e___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d2lp4y__d3ltee1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	DNA binding [GO:0003677]
d2lq9a__d2lqba1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper ion binding [GO:0005507]; copper-dependent protein binding [GO:0032767]; metallochaperone activity [GO:0016530]; cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; protein maturation by copper ion transfer [GO:0015680]; response to copper ion [GO:0046688]; sequestering of calcium ion [GO:0051208]	cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; protein maturation by copper ion transfer [GO:0015680]; response to copper ion [GO:0046688]; sequestering of calcium ion [GO:0051208]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]	ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; metallochaperone activity [GO:0016530]	ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]
d2lqia__d5u4ka___1	Metazoa	Metazoa	Chordata	Chordata	condensed chromosome outer kinetochore [GO:0000940]; cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor complex [GO:0005667]; acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; cAMP response element binding protein binding [GO:0008140]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; SMAD binding [GO:0046332]; TFIIB-class transcription factor binding [GO:0001093]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of interferon-beta biosynthetic process [GO:0045358]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular defense response [GO:0006968]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; Fc-epsilon receptor signaling pathway [GO:0038095]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; liver development [GO:0001889]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; negative regulation of interferon-beta biosynthetic process [GO:0045358]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular defense response [GO:0006968]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; Fc-epsilon receptor signaling pathway [GO:0038095]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; liver development [GO:0001889]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of type I interferon production [GO:0032481]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	condensed chromosome outer kinetochore [GO:0000940]; cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; cAMP response element binding protein binding [GO:0008140]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; SMAD binding [GO:0046332]; TFIIB-class transcription factor binding [GO:0001093]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]
d2lqqa1_d2mbsa1__1			Actinobacteria	Proteobacteria	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]; periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d2lrba__d1d0na3__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]		actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]		cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]		actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d2lrla__d3l8re___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity [GO:0090566]; N,N'-diacetylchitobiose import [GO:1902815]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; protein homooligomerization [GO:0051260]	metal ion binding [GO:0046872]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	N,N'-diacetylchitobiose import [GO:1902815]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; protein homooligomerization [GO:0051260]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytosol [GO:0005829]		protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity [GO:0090566]	metal ion binding [GO:0046872]
d2lrna1_d11gsa2__1		Metazoa	Bacteroidetes	Chordata	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2ls8a1_d1tlga___1	Metazoa	Metazoa	Chordata	Chordata	ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; immunoglobulin receptor binding [GO:0034987]; metal ion binding [GO:0046872]; adaptive immune response [GO:0002250]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway [GO:0038094]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of myeloid dendritic cell activation [GO:0030887]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell differentiation involved in immune response [GO:0002292]	carbohydrate binding [GO:0030246]	adaptive immune response [GO:0002250]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway [GO:0038094]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of myeloid dendritic cell activation [GO:0030887]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell differentiation involved in immune response [GO:0002292]		ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		carbohydrate binding [GO:0030246]; immunoglobulin receptor binding [GO:0034987]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d2ltka1_d1q98a___1				Proteobacteria	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	thioredoxin peroxidase activity [GO:0008379]
d2luca__d1nubb1__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; neutrophil degranulation [GO:0043312]; signal transduction [GO:0007165]	basement membrane [GO:0005604]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; nuclear matrix [GO:0016363]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; platelet alpha granule membrane [GO:0031092]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; extracellular matrix binding [GO:0050840]; bone development [GO:0060348]; cellular response to growth factor stimulus [GO:0071363]; extracellular matrix organization [GO:0030198]; heart development [GO:0007507]; inner ear development [GO:0048839]; lung development [GO:0030324]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; ossification [GO:0001503]; pigmentation [GO:0043473]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; receptor-mediated endocytosis [GO:0006898]; regulation of cell morphogenesis [GO:0022604]; regulation of synapse organization [GO:0050807]; response to cadmium ion [GO:0046686]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to gravity [GO:0009629]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; wound healing [GO:0042060]	negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; neutrophil degranulation [GO:0043312]; signal transduction [GO:0007165]	bone development [GO:0060348]; cellular response to growth factor stimulus [GO:0071363]; extracellular matrix organization [GO:0030198]; heart development [GO:0007507]; inner ear development [GO:0048839]; lung development [GO:0030324]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; ossification [GO:0001503]; pigmentation [GO:0043473]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; receptor-mediated endocytosis [GO:0006898]; regulation of cell morphogenesis [GO:0022604]; regulation of synapse organization [GO:0050807]; response to cadmium ion [GO:0046686]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to gravity [GO:0009629]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; wound healing [GO:0042060]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	basement membrane [GO:0005604]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; nuclear matrix [GO:0016363]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; platelet alpha granule membrane [GO:0031092]	cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; extracellular matrix binding [GO:0050840]
d2luoa1_d1bvha___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; host cell endosome [GO:0044174]; plasma membrane [GO:0005886]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]; acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]	negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein dephosphorylation [GO:0006470]		extracellular region [GO:0005576]; host cell endosome [GO:0044174]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	protein tyrosine phosphatase activity [GO:0004725]	acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]
d2luxb__d4xjka___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d2lvia__d1h4ba___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]					calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]
d2lvka__d2ktga___1	Viridiplantae		Streptophyta		calcium ion binding [GO:0005509]						calcium ion binding [GO:0005509]	
d2lw8a1_d1kgya___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; axon [GO:0030424]; axon terminus [GO:0043679]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; mitochondrial outer membrane [GO:0005741]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; DH domain binding [GO:0097161]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; PH domain binding [GO:0042731]; protein kinase activity [GO:0004672]; protein tyrosine kinase binding [GO:1990782]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to amyloid-beta [GO:1904646]; cochlea development [GO:0090102]; corticospinal tract morphogenesis [GO:0021957]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; negative regulation of axon regeneration [GO:0048681]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron projection development [GO:0010977]; negative regulation of proteolysis involved in cellular protein catabolic process [GO:1903051]; nephric duct morphogenesis [GO:0072178]; neuron projection fasciculation [GO:0106030]; neuron projection guidance [GO:0097485]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of astrocyte differentiation [GO:0048710]; regulation of axonogenesis [GO:0050770]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of modification of synaptic structure [GO:1905244]; synapse pruning [GO:0098883]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to amyloid-beta [GO:1904646]; cochlea development [GO:0090102]; corticospinal tract morphogenesis [GO:0021957]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; negative regulation of axon regeneration [GO:0048681]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron projection development [GO:0010977]; negative regulation of proteolysis involved in cellular protein catabolic process [GO:1903051]; nephric duct morphogenesis [GO:0072178]; neuron projection fasciculation [GO:0106030]; neuron projection guidance [GO:0097485]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of astrocyte differentiation [GO:0048710]; regulation of axonogenesis [GO:0050770]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of modification of synaptic structure [GO:1905244]; synapse pruning [GO:0098883]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]	adherens junction [GO:0005912]; axon [GO:0030424]; axonal growth cone [GO:0044295]; axon terminus [GO:0043679]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; mitochondrial outer membrane [GO:0005741]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; DH domain binding [GO:0097161]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; PH domain binding [GO:0042731]; protein kinase activity [GO:0004672]; protein tyrosine kinase binding [GO:1990782]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2lwpa__d4bbnf___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; phosphoprotein binding [GO:0051219]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; negative regulation of motor neuron apoptotic process [GO:2000672]; negative regulation of protein phosphorylation [GO:0001933]; neuron differentiation [GO:0030182]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to mitochondrion [GO:0070585]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	apoptotic process [GO:0006915]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; negative regulation of motor neuron apoptotic process [GO:2000672]; negative regulation of protein phosphorylation [GO:0001933]; neuron differentiation [GO:0030182]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to mitochondrion [GO:0070585]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; phosphoprotein binding [GO:0051219]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2lxca1_d4kslx2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]; cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2lxia__d2ghpc2__1	Metazoa	Fungi	Chordata	Ascomycota	nuclear speck [GO:0016607]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA processing [GO:0006397]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA processing [GO:0006397]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	nuclear speck [GO:0016607]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ribonucleoprotein complex [GO:1990904]; U6 snRNP [GO:0005688]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]	RNA binding [GO:0003723]; snRNA binding [GO:0017069]; U6 snRNA binding [GO:0017070]
d2lxxa__d1d0nb1__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; striated muscle thin filament [GO:0005865]; actin filament binding [GO:0051015]; actin filament depolymerization [GO:0030042]; actin filament severing [GO:0051014]; embryo development ending in birth or egg hatching [GO:0009792]; locomotion [GO:0040011]; positive regulation of actin filament polymerization [GO:0030838]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament depolymerization [GO:0030042]; actin filament severing [GO:0051014]; embryo development ending in birth or egg hatching [GO:0009792]; locomotion [GO:0040011]; positive regulation of actin filament polymerization [GO:0030838]; skeletal muscle thin filament assembly [GO:0030240]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; striated muscle thin filament [GO:0005865]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin filament binding [GO:0051015]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d2lxxa__d2fgha3__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; striated muscle thin filament [GO:0005865]; actin filament binding [GO:0051015]; actin filament depolymerization [GO:0030042]; actin filament severing [GO:0051014]; embryo development ending in birth or egg hatching [GO:0009792]; locomotion [GO:0040011]; positive regulation of actin filament polymerization [GO:0030838]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament depolymerization [GO:0030042]; actin filament severing [GO:0051014]; embryo development ending in birth or egg hatching [GO:0009792]; locomotion [GO:0040011]; positive regulation of actin filament polymerization [GO:0030838]; skeletal muscle thin filament assembly [GO:0030240]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; striated muscle thin filament [GO:0005865]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin filament binding [GO:0051015]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d2lyma__d3c81a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2lyva2_d4cq1a2__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d2lyza__d259la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2lzma__d1xgqc___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2lzma__d4i7lb1__1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2lzta__d4kl7d___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; dormancy exit of symbiont in host [GO:0085016]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	dormancy exit of symbiont in host [GO:0085016]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	hydrolase activity [GO:0016787]
d2m08a1_d1m5ya2__1			Thaumarchaeota	Proteobacteria	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	outer membrane-bounded periplasmic space [GO:0030288]; peptide binding [GO:0042277]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; chaperone cofactor-dependent protein refolding [GO:0051085]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; maintenance of stationary phase [GO:0060274]; protein folding [GO:0006457]; protein stabilization [GO:0050821]		chaperone cofactor-dependent protein refolding [GO:0051085]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; maintenance of stationary phase [GO:0060274]; protein folding [GO:0006457]; protein stabilization [GO:0050821]		outer membrane-bounded periplasmic space [GO:0030288]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptide binding [GO:0042277]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]
d2m0ka__d1kfxs___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d2m0ta1_d4jojb___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]; beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein-containing complex assembly [GO:0065003]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]	ion channel binding [GO:0044325]
d2m0ua1_d1obza2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]; beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]	actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein-containing complex assembly [GO:0065003]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]
d2m10a1_d3nfka___1	Metazoa	Metazoa	Chordata	Chordata	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; cytoskeletal protein binding [GO:0008092]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; cellular response to cytokine stimulus [GO:0071345]; protein dephosphorylation [GO:0006470]	cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	cellular response to cytokine stimulus [GO:0071345]; protein dephosphorylation [GO:0006470]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]	cytoskeletal protein binding [GO:0008092]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]
d2m17a__d3vuxc___1	Metazoa	Metazoa	Chordata	Chordata	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein serine/threonine phosphatase activity [GO:0004722]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	protein dephosphorylation [GO:0006470]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	protein serine/threonine phosphatase activity [GO:0004722]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2m1kd__d2l4ha___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; advanced glycation end-product receptor activity [GO:0050785]; amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; S100 protein binding [GO:0044548]; scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; astrocyte activation [GO:0048143]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; glucose mediated signaling pathway [GO:0010255]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of blood circulation [GO:1903523]; negative regulation of connective tissue replacement involved in inflammatory response wound healing [GO:1904597]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of long-term synaptic potentiation [GO:1900272]; neuron projection development [GO:0031175]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein localization to membrane [GO:0072657]; regulation of CD4-positive, alpha-beta T cell activation [GO:2000514]; regulation of DNA binding [GO:0051101]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of p38MAPK cascade [GO:1900744]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell mediated cytotoxicity [GO:0001914]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to wounding [GO:0009611]; transcytosis [GO:0045056]	apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; filopodium tip [GO:0032433]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; calcium-dependent protein kinase inhibitor activity [GO:0008427]; ion channel binding [GO:0044325]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein membrane anchor [GO:0043495]; protein serine/threonine kinase inhibitor activity [GO:0030291]; Ras GTPase binding [GO:0017016]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to growth factor stimulus [GO:0071363]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; cytoplasmic microtubule organization [GO:0031122]; double-strand break repair [GO:0006302]; endomitotic cell cycle [GO:0007113]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; platelet formation [GO:0030220]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of male germ cell proliferation [GO:2000256]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of cell division [GO:0051302]; regulation of cell population proliferation [GO:0042127]; response to ischemia [GO:0002931]; spermatid development [GO:0007286]; thrombopoietin-mediated signaling pathway [GO:0038163]	astrocyte activation [GO:0048143]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; glucose mediated signaling pathway [GO:0010255]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of blood circulation [GO:1903523]; negative regulation of connective tissue replacement involved in inflammatory response wound healing [GO:1904597]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of long-term synaptic potentiation [GO:1900272]; neuron projection development [GO:0031175]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein localization to membrane [GO:0072657]; regulation of CD4-positive, alpha-beta T cell activation [GO:2000514]; regulation of DNA binding [GO:0051101]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of p38MAPK cascade [GO:1900744]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell mediated cytotoxicity [GO:0001914]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to wounding [GO:0009611]; transcytosis [GO:0045056]	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to growth factor stimulus [GO:0071363]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; cytoplasmic microtubule organization [GO:0031122]; double-strand break repair [GO:0006302]; endomitotic cell cycle [GO:0007113]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; platelet formation [GO:0030220]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of male germ cell proliferation [GO:2000256]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of cell division [GO:0051302]; regulation of cell population proliferation [GO:0042127]; response to ischemia [GO:0002931]; spermatid development [GO:0007286]; thrombopoietin-mediated signaling pathway [GO:0038163]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; filopodium tip [GO:0032433]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; vesicle [GO:0031982]	advanced glycation end-product receptor activity [GO:0050785]; amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; S100 protein binding [GO:0044548]; scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]	calcium-dependent protein kinase inhibitor activity [GO:0008427]; calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein membrane anchor [GO:0043495]; protein serine/threonine kinase inhibitor activity [GO:0030291]; Ras GTPase binding [GO:0017016]
d2m2da1_d1cbvl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	metal ion binding [GO:0046872]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]			metal ion binding [GO:0046872]
d2m2da1_d3b2ud2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2m30a__d5u79a1__1			Firmicutes	Proteobacteria	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	alkylmercury lyase activity [GO:0018836]; organomercury catabolic process [GO:0046413]; response to mercury ion [GO:0046689]		organomercury catabolic process [GO:0046413]; response to mercury ion [GO:0046689]			DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	alkylmercury lyase activity [GO:0018836]
d2m30b__d1r1va___1			Firmicutes	Firmicutes	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]					DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2m33a__d1sv7a___1	Metazoa		Chordata		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]		enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d2m3ca1_d3snza___1	Metazoa		Chordata	Firmicutes	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d2m3ca2_d1blbb1__1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			structural constituent of eye lens [GO:0005212]	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]
d2m3ca2_d3so1a___1	Metazoa		Chordata	Firmicutes	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	metal ion binding [GO:0046872]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	metal ion binding [GO:0046872]
d2m3da1_d2lyva1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; rRNA binding [GO:0019843]; snoRNA binding [GO:0030515]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; osteoblast differentiation [GO:0001649]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; response to exogenous dsRNA [GO:0043330]; rRNA processing [GO:0006364]; transcription by RNA polymerase II [GO:0006366]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; osteoblast differentiation [GO:0001649]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; response to exogenous dsRNA [GO:0043330]; rRNA processing [GO:0006364]; transcription by RNA polymerase II [GO:0006366]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; rRNA binding [GO:0019843]; snoRNA binding [GO:0030515]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]
d2m3da1_d2ytca1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; rRNA binding [GO:0019843]; snoRNA binding [GO:0030515]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; osteoblast differentiation [GO:0001649]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; response to exogenous dsRNA [GO:0043330]; rRNA processing [GO:0006364]; transcription by RNA polymerase II [GO:0006366]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]; calcium-dependent protein binding [GO:0048306]; metal ion binding [GO:0046872]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; U6 snRNA binding [GO:0017070]; cellular response to drug [GO:0035690]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of RNA splicing [GO:0033120]	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; osteoblast differentiation [GO:0001649]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; response to exogenous dsRNA [GO:0043330]; rRNA processing [GO:0006364]; transcription by RNA polymerase II [GO:0006366]	cellular response to drug [GO:0035690]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of RNA splicing [GO:0033120]	cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; rRNA binding [GO:0019843]; snoRNA binding [GO:0030515]	calcium-dependent protein binding [GO:0048306]; metal ion binding [GO:0046872]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; U6 snRNA binding [GO:0017070]
d2m3ma1_d2ogpa___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]; cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; axonal growth cone [GO:0044295]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell cortex [GO:0005938]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; endomembrane system [GO:0012505]; internode region of axon [GO:0033269]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein phosphatase binding [GO:0019903]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; protein localization [GO:0008104]; protein targeting to membrane [GO:0006612]; regulation of cellular localization [GO:0060341]	actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; protein localization [GO:0008104]; protein targeting to membrane [GO:0006612]; regulation of cellular localization [GO:0060341]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; axonal growth cone [GO:0044295]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; endomembrane system [GO:0012505]; internode region of axon [GO:0033269]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]	cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]	identical protein binding [GO:0042802]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol binding [GO:0035091]; protein phosphatase binding [GO:0019903]
d2m3ta1_d1a5da1__1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d2m3ta2_d1a5db1__1	Metazoa	Metazoa	Chordata	Chordata	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d2m3ua1_d2kp5a___1	Metazoa		Chordata	Proteobacteria	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]				structural constituent of eye lens [GO:0005212]	
d2m56b__d4kx6b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane fumarate reductase complex [GO:0045284]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; fumarate metabolic process [GO:0006106]	(+)-camphor catabolic process [GO:0019383]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; fumarate metabolic process [GO:0006106]	cytoplasm [GO:0005737]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane fumarate reductase complex [GO:0045284]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d2m5ca__d4pvoa___1			Firmicutes	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d2m65a__d2z3ia___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular response to xenobiotic stimulus [GO:0071466]; clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine [GO:0044356]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cellular response to xenobiotic stimulus [GO:0071466]; clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine [GO:0044356]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]		cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d2m66a__d1ovnb1__1	Metazoa	Metazoa	Chordata	Arthropoda	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; melanosome [GO:0042470]; smooth endoplasmic reticulum [GO:0005790]; transport vesicle [GO:0030133]; chaperone binding [GO:0051087]; protein homodimerization activity [GO:0042803]; activation of MAPK activity [GO:0000187]; intracellular protein transport [GO:0006886]; negative regulation of gene expression [GO:0010629]; negative regulation of protein secretion [GO:0050709]; positive regulation of gene expression [GO:0010628]; protein folding [GO:0006457]; protein secretion [GO:0009306]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; response to endoplasmic reticulum stress [GO:0034976]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; protein homodimerization activity [GO:0042803]; dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	activation of MAPK activity [GO:0000187]; intracellular protein transport [GO:0006886]; negative regulation of gene expression [GO:0010629]; negative regulation of protein secretion [GO:0050709]; positive regulation of gene expression [GO:0010628]; protein folding [GO:0006457]; protein secretion [GO:0009306]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; response to endoplasmic reticulum stress [GO:0034976]	dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; melanosome [GO:0042470]; smooth endoplasmic reticulum [GO:0005790]; transport vesicle [GO:0030133]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	chaperone binding [GO:0051087]; protein homodimerization activity [GO:0042803]	protein homodimerization activity [GO:0042803]
d2m6la__d1qh8a___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; cellular response to DNA damage stimulus [GO:0006974]; ferric-enterobactin import into cell [GO:0015685]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cellular response to DNA damage stimulus [GO:0006974]; ferric-enterobactin import into cell [GO:0015685]	nitrogen fixation [GO:0009399]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2m6sa__d4dika2__1			Proteobacteria	Thermotogae	FMN binding [GO:0010181]; oxidation-reduction process [GO:0055114]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	oxidation-reduction process [GO:0055114]				FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d2m6ya1_d3ucsd___1	Metazoa		Chordata	Proteobacteria	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ATP binding [GO:0005524]; ATPase activator activity [GO:0001671]; C3HC4-type RING finger domain binding [GO:0055131]; chaperone binding [GO:0051087]; G protein-coupled receptor binding [GO:0001664]; Hsp70 protein binding [GO:0030544]; low-density lipoprotein particle receptor binding [GO:0050750]; metal ion binding [GO:0046872]; Tat protein binding [GO:0030957]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; androgen receptor signaling pathway [GO:0030521]; DNA damage response, detection of DNA damage [GO:0042769]; flagellated sperm motility [GO:0030317]; negative regulation of apoptotic process [GO:0043066]; negative regulation of establishment of protein localization to mitochondrion [GO:1903748]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatogenesis [GO:0007283]; toxin transport [GO:1901998]	cytoplasm [GO:0005737]; nucleoid [GO:0009295]; bent DNA binding [GO:0003681]; unfolded protein binding [GO:0051082]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein refolding [GO:0042026]	androgen receptor signaling pathway [GO:0030521]; DNA damage response, detection of DNA damage [GO:0042769]; flagellated sperm motility [GO:0030317]; negative regulation of apoptotic process [GO:0043066]; negative regulation of establishment of protein localization to mitochondrion [GO:1903748]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatogenesis [GO:0007283]; toxin transport [GO:1901998]	chaperone cofactor-dependent protein refolding [GO:0051085]; protein refolding [GO:0042026]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cytoplasm [GO:0005737]; nucleoid [GO:0009295]	ATPase activator activity [GO:0001671]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; chaperone binding [GO:0051087]; G protein-coupled receptor binding [GO:0001664]; Hsp70 protein binding [GO:0030544]; low-density lipoprotein particle receptor binding [GO:0050750]; metal ion binding [GO:0046872]; Tat protein binding [GO:0030957]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	bent DNA binding [GO:0003681]; unfolded protein binding [GO:0051082]
d2m6zc__d3mn0a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2m7ka__d3fs7d___1		Metazoa		Chordata	calcium ion binding [GO:0005509]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]				cytoplasm [GO:0005737]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]
d2m7ua1_d3c2wd1__1			Cyanobacteria	Proteobacteria	integral component of membrane [GO:0016021]; protein-chromophore linkage [GO:0018298]; signal transduction [GO:0007165]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	protein-chromophore linkage [GO:0018298]; signal transduction [GO:0007165]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	integral component of membrane [GO:0016021]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d2m8pa2_d3dphb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2m8wa1_d2k1ha___1			Firmicutes	Firmicutes								
d2ma9b__d3dowa1__1	Metazoa	Metazoa	Chordata	Chordata	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; synapse [GO:0045202]; beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; chemical synaptic transmission [GO:0007268]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein targeting [GO:0006605]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; chemical synaptic transmission [GO:0007268]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein targeting [GO:0006605]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; synapse [GO:0045202]	ubiquitin protein ligase binding [GO:0031625]	beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d2ma9c__d5bxbg1__1	Metazoa	Metazoa	Chordata	Chordata	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; identical protein binding [GO:0042802]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; protein homooligomerization [GO:0051260]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein homooligomerization [GO:0051260]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]
d2madh__d2gc4e___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]; methylamine metabolic process [GO:0030416]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	methylamine metabolic process [GO:0030416]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2maza__d3fwce___1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]; chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]; histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]		histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]
d2mb0b__d5ddog___1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; supraspliceosomal complex [GO:0044530]; chromatin binding [GO:0003682]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded RNA binding [GO:0003727]; cellular response to interleukin-1 [GO:0071347]; membrane protein ectodomain proteolysis [GO:0006509]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; osteoblast differentiation [GO:0001649]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; transcription by RNA polymerase II [GO:0006366]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cellular response to interleukin-1 [GO:0071347]; membrane protein ectodomain proteolysis [GO:0006509]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; osteoblast differentiation [GO:0001649]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; transcription by RNA polymerase II [GO:0006366]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	catalytic step 2 spliceosome [GO:0071013]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; supraspliceosomal complex [GO:0044530]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	chromatin binding [GO:0003682]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded RNA binding [GO:0003727]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]
d2mbqa__d4aswc___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]; cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]
d2mbqb__d5hpsb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d2mbsa1_d1bq7a___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; periplasmic space [GO:0042597]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d2mcg11_d3b5hd1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]	antigen binding [GO:0003823]	cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]
d2mcg12_d3l5xl1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	antigen binding [GO:0003823]	cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]
d2mcg21_d5hysf2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2mcg22_d1bvld___1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]	
d2mcph1_d5eiqa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; collagen receptor activity [GO:0038064]; neutrophil degranulation [GO:0043312]; osteoclast differentiation [GO:0030316]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	neutrophil degranulation [GO:0043312]; osteoclast differentiation [GO:0030316]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	collagen receptor activity [GO:0038064]
d2mcpl1_d1f8th1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2mcpl2_d4jn2l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2md5a1_d1awca___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; vitellogenesis [GO:0007296]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription regulatory region DNA binding [GO:0044212]; blastocyst formation [GO:0001825]; cell differentiation [GO:0030154]; cellular response to dopamine [GO:1903351]; in utero embryonic development [GO:0001701]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; vitellogenesis [GO:0007296]	blastocyst formation [GO:0001825]; cell differentiation [GO:0030154]; cellular response to dopamine [GO:1903351]; in utero embryonic development [GO:0001701]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleus [GO:0005634]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription regulatory region DNA binding [GO:0044212]
d2md9a1_d3ejdg2__1			Firmicutes	Proteobacteria	hydrolase activity, acting on ester bonds [GO:0016788]; ligase activity [GO:0016874]; phosphopantetheine binding [GO:0031177]; antibiotic biosynthetic process [GO:0017000]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	antibiotic biosynthetic process [GO:0017000]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	hydrolase activity, acting on ester bonds [GO:0016788]; ligase activity [GO:0016874]; phosphopantetheine binding [GO:0031177]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]
d2meda__d1ucoa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2mega__d4s0wb___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2mega__d5k2na___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2mejb__d3d0ac___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d2mev.1_d1ar73___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2mev.1_d2df7l___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; viral capsid [GO:0019028]; host cell surface binding [GO:0046812]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]	induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell cytoplasm [GO:0030430]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	host cell surface binding [GO:0046812]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]
d2mgba__d3uhua___1	Metazoa	Metazoa	Chordata	Mollusca	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2mgca__d1y09a___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2mgda__d1o1lb___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2mgea__d2uule___1	Metazoa		Chordata		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2mgga__d4n7pa___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2mgha__d2nsra___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2mgka__d1fn3d___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2mgua__d3gk1a___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d2mgzb1_d2kfya___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	nuclear speck [GO:0016607]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; pre-mRNA intronic binding [GO:0097157]; single-stranded RNA binding [GO:0003727]; alternative mRNA splicing, via spliceosome [GO:0000380]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of locomotion [GO:0040012]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; TBP-class protein binding [GO:0017025]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-12-mediated signaling pathway [GO:0035722]; mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	alternative mRNA splicing, via spliceosome [GO:0000380]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of locomotion [GO:0040012]	fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-12-mediated signaling pathway [GO:0035722]; mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	nuclear speck [GO:0016607]; ribonucleoprotein complex [GO:1990904]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; pre-mRNA intronic binding [GO:0097157]; single-stranded RNA binding [GO:0003727]	RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; TBP-class protein binding [GO:0017025]
d2mhaa1_d1rmfh1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2mhaa1_d1w72b1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2mhab__d1q9kb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2mhac1_d1bvke1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2mhbb__d5nb3l___1	Metazoa		Chordata	Cyanobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2mhja1_d2qdfa2__1			Proteobacteria	Proteobacteria	type V protein secretion system complex [GO:0098046]; protein transmembrane transporter activity [GO:0008320]; protein secretion by the type V secretion system [GO:0046819]	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	protein secretion by the type V secretion system [GO:0046819]	cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	type V protein secretion system complex [GO:0098046]	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	protein transmembrane transporter activity [GO:0008320]	
d2mhna1_d2fc9a1__1	Metazoa	Metazoa	Chordata	Chordata	centriolar satellite [GO:0034451]; microtubule cytoskeleton [GO:0015630]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; RNA binding [GO:0003723]; mRNA processing [GO:0006397]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]	cell cortex [GO:0005938]; cytoplasmic ribonucleoprotein granule [GO:0036464]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; DNA topoisomerase binding [GO:0044547]; identical protein binding [GO:0042802]; mRNA 5'-UTR binding [GO:0048027]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]; angiogenesis [GO:0001525]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to leukemia inhibitory factor [GO:1990830]; negative regulation of translation [GO:0017148]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]	mRNA processing [GO:0006397]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]	angiogenesis [GO:0001525]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to leukemia inhibitory factor [GO:1990830]; negative regulation of translation [GO:0017148]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]	centriolar satellite [GO:0034451]; microtubule cytoskeleton [GO:0015630]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	cell cortex [GO:0005938]; cytoplasmic ribonucleoprotein granule [GO:0036464]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	RNA binding [GO:0003723]	DNA topoisomerase binding [GO:0044547]; identical protein binding [GO:0042802]; mRNA 5'-UTR binding [GO:0048027]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]
d2minb__d1qh1c___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2mipc__d5isja___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2mj3a__d2w3rc1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d2mjba__d2bwet___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; nucleus [GO:0005634]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein binding, bridging [GO:0030674]; protein localization to vacuole [GO:0072665]; spindle pole body duplication [GO:0030474]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	protein localization to vacuole [GO:0072665]; spindle pole body duplication [GO:0030474]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]	cytosol [GO:0005829]; nucleus [GO:0005634]	protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]	polyubiquitin modification-dependent protein binding [GO:0031593]; protein binding, bridging [GO:0030674]
d2mjda__d5c2tf1__1	Fungi	Metazoa	Ascomycota	Nematoda (roundworms)	mitochondrial matrix [GO:0005759]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; heme a biosynthetic process [GO:0006784]; iron-sulfur cluster assembly [GO:0016226]; ubiquinone biosynthetic process [GO:0006744]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	heme a biosynthetic process [GO:0006784]; iron-sulfur cluster assembly [GO:0016226]; ubiquinone biosynthetic process [GO:0006744]	tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d2mjea__d1zxid2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial matrix [GO:0005759]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; heme a biosynthetic process [GO:0006784]; iron-sulfur cluster assembly [GO:0016226]; ubiquinone biosynthetic process [GO:0006744]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	heme a biosynthetic process [GO:0006784]; iron-sulfur cluster assembly [GO:0016226]; ubiquinone biosynthetic process [GO:0006744]		mitochondrial matrix [GO:0005759]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2mjha__d1viga___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P granule [GO:0043186]; mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; negative regulation of gene expression [GO:0010629]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; negative regulation of translation [GO:0017148]; oocyte fate determination [GO:0030716]; oogenesis [GO:0048477]; positive regulation of female gonad development [GO:2000196]; positive regulation of oocyte development [GO:0060282]; regulation of gene expression [GO:0010468]; regulation of germ cell proliferation [GO:1905936]	cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]	meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; negative regulation of gene expression [GO:0010629]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; negative regulation of translation [GO:0017148]; oocyte fate determination [GO:0030716]; oogenesis [GO:0048477]; positive regulation of female gonad development [GO:2000196]; positive regulation of oocyte development [GO:0060282]; regulation of gene expression [GO:0010468]; regulation of germ cell proliferation [GO:1905936]	cholesterol metabolic process [GO:0008203]; high-density lipoprotein particle clearance [GO:0034384]; lipid transport [GO:0006869]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P granule [GO:0043186]	cytosol [GO:0005829]; high-density lipoprotein particle [GO:0034364]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	mRNA 3'-UTR binding [GO:0003730]; mRNA 5'-UTR binding [GO:0048027]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]	cadherin binding [GO:0045296]; lipid binding [GO:0008289]; RNA binding [GO:0003723]
d2mjia__d4xmda___1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; negative regulation of coagulation [GO:0050819]; nitric oxide homeostasis [GO:0033484]; platelet aggregation [GO:0070527]; positive regulation of blood vessel diameter [GO:0097755]; response to histamine [GO:0034776]; vasodilation [GO:0042311]	intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	negative regulation of coagulation [GO:0050819]; nitric oxide homeostasis [GO:0033484]; platelet aggregation [GO:0070527]; positive regulation of blood vessel diameter [GO:0097755]; response to histamine [GO:0034776]; vasodilation [GO:0042311]	cytosol [GO:0005829]	extracellular region [GO:0005576]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d2mjua1_d4ckoa3__1	Metazoa		Chordata		growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]		cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]		growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]		mRNA binding [GO:0003729]; RNA binding [GO:0003723]	
d2mjua2_d5uzga___1	Metazoa	Metazoa	Chordata	Arthropoda	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	protein-containing complex [GO:0032991]; mRNA binding [GO:0003729]; chromosome organization [GO:0051276]; intracellular mRNA localization involved in pattern specification process [GO:0060810]; maternal specification of dorsal/ventral axis, oocyte, germ-line encoded [GO:0007311]; pole plasm oskar mRNA localization [GO:0045451]; regulation of translation [GO:0006417]; wound healing [GO:0042060]	cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	chromosome organization [GO:0051276]; intracellular mRNA localization involved in pattern specification process [GO:0060810]; maternal specification of dorsal/ventral axis, oocyte, germ-line encoded [GO:0007311]; pole plasm oskar mRNA localization [GO:0045451]; regulation of translation [GO:0006417]; wound healing [GO:0042060]	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]	protein-containing complex [GO:0032991]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	mRNA binding [GO:0003729]
d2mkra__d2rvbb___1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]; nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 2 complex [GO:0000111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of DNA damage [GO:0090734]; XPC complex [GO:0071942]; bubble DNA binding [GO:0000405]; damaged DNA binding [GO:0003684]; heteroduplex DNA loop binding [GO:0000404]; protein-containing complex binding [GO:0044877]; single-stranded DNA binding [GO:0003697]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; intra-S DNA damage checkpoint [GO:0031573]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to UV-B [GO:0010224]; UV-damage excision repair [GO:0070914]; UV-damage excision repair, DNA incision [GO:1990731]	nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; intra-S DNA damage checkpoint [GO:0031573]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to UV-B [GO:0010224]; UV-damage excision repair [GO:0070914]; UV-damage excision repair, DNA incision [GO:1990731]	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 2 complex [GO:0000111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of DNA damage [GO:0090734]; XPC complex [GO:0071942]	phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]	bubble DNA binding [GO:0000405]; damaged DNA binding [GO:0003684]; heteroduplex DNA loop binding [GO:0000404]; protein-containing complex binding [GO:0044877]; single-stranded DNA binding [GO:0003697]
d2mkra__d5c5ba2__1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]; nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; intracellular vesicle [GO:0097708]; macropinosome [GO:0044354]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; vesicle membrane [GO:0012506]; beta-tubulin binding [GO:0048487]; identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; protein kinase B binding [GO:0043422]; protein-containing complex binding [GO:0044877]; adiponectin-activated signaling pathway [GO:0033211]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; insulin receptor signaling pathway [GO:0008286]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of glucose import [GO:0046326]; positive regulation of macropinocytosis [GO:1905303]; positive regulation of melanin biosynthetic process [GO:0048023]; protein import into nucleus [GO:0006606]; regulation of fibroblast migration [GO:0010762]; regulation of glucose import [GO:0046324]; regulation of innate immune response [GO:0045088]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of toll-like receptor 4 signaling pathway [GO:0034143]; signal transduction [GO:0007165]; signaling [GO:0023052]; transforming growth factor beta receptor signaling pathway [GO:0007179]	nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	adiponectin-activated signaling pathway [GO:0033211]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; insulin receptor signaling pathway [GO:0008286]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of glucose import [GO:0046326]; positive regulation of macropinocytosis [GO:1905303]; positive regulation of melanin biosynthetic process [GO:0048023]; protein import into nucleus [GO:0006606]; regulation of fibroblast migration [GO:0010762]; regulation of glucose import [GO:0046324]; regulation of innate immune response [GO:0045088]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of toll-like receptor 4 signaling pathway [GO:0034143]; signaling [GO:0023052]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; intracellular vesicle [GO:0097708]; macropinosome [GO:0044354]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; vesicle membrane [GO:0012506]	phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]	beta-tubulin binding [GO:0048487]; identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; protein kinase B binding [GO:0043422]
d2mksa1_d5lxya___1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; supraspliceosomal complex [GO:0044530]; chromatin binding [GO:0003682]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded RNA binding [GO:0003727]; cellular response to interleukin-1 [GO:0071347]; membrane protein ectodomain proteolysis [GO:0006509]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; osteoblast differentiation [GO:0001649]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; transcription by RNA polymerase II [GO:0006366]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 14-3-3 protein binding [GO:0071889]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]; meiotic cell cycle [GO:0051321]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; snRNA catabolic process [GO:0016076]	cellular response to interleukin-1 [GO:0071347]; membrane protein ectodomain proteolysis [GO:0006509]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; osteoblast differentiation [GO:0001649]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; transcription by RNA polymerase II [GO:0006366]	meiotic cell cycle [GO:0051321]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; snRNA catabolic process [GO:0016076]	catalytic step 2 spliceosome [GO:0071013]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; supraspliceosomal complex [GO:0044530]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; identical protein binding [GO:0042802]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded RNA binding [GO:0003727]	14-3-3 protein binding [GO:0071889]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]
d2mkwa1_d2wzpk1__1	Metazoa		Chordata			virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		virus tail, baseplate [GO:0098025]		
d2mlfc__d3tuyc___1	Metazoa	Metazoa	Chordata	Mollusca	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	myosin complex [GO:0016459]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]		cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]	myosin complex [GO:0016459]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]
d2mllb2_d3ca6a1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2mlma1_d1ng5a___1				Firmicutes								
d2mlxa2_d4lava1__1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein-containing complex localization [GO:0031503]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein-containing complex localization [GO:0031503]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]
d2mlya2_d1t11a3__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; 'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein transport [GO:0015031]; protein unfolding [GO:0043335]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein transport [GO:0015031]; protein unfolding [GO:0043335]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cytoplasm [GO:0005737]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]
d2mlya3_d5owja3__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; 'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]; response to heat [GO:0009408]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]; response to heat [GO:0009408]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cytosol [GO:0005829]; membrane [GO:0016020]	alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]
d2mlza2_d4drna1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; 'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	'de novo' cotranslational protein folding [GO:0051083]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone-mediated protein folding [GO:0061077]; protein transport [GO:0015031]; protein unfolding [GO:0043335]; response to heat [GO:0009408]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2mmca__d4obea___1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]; actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]
d2mmna1_d1g0tb1__1			Apicomplexa	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d2mmxa1_d1zvob1__1	Metazoa	Metazoa	Chordata	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2mmxa1_d2a38b1__1	Metazoa	Metazoa	Chordata	Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d2mmya1_d3p6yc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; mRNA stabilization [GO:0048255]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA splicing [GO:0008380]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	mRNA stabilization [GO:0048255]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA splicing [GO:0008380]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]	exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]
d2mnga1_d3h3ub1__1	Metazoa		Chordata	Actinobacteria	HCN channel complex [GO:0098855]; intrinsic component of plasma membrane [GO:0031226]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated potassium channel activity involved in SA node cell action potential depolarization [GO:0086041]; voltage-gated sodium channel activity [GO:0005248]; blood circulation [GO:0008015]; cation transport [GO:0006812]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; membrane depolarization during SA node cell action potential [GO:0086046]; muscle contraction [GO:0006936]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane depolarization [GO:0003254]; regulation of membrane potential [GO:0042391]; SA node cell action potential [GO:0086015]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	blood circulation [GO:0008015]; cation transport [GO:0006812]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; membrane depolarization during SA node cell action potential [GO:0086046]; muscle contraction [GO:0006936]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane depolarization [GO:0003254]; regulation of membrane potential [GO:0042391]; SA node cell action potential [GO:0086015]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	HCN channel complex [GO:0098855]; intrinsic component of plasma membrane [GO:0031226]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated potassium channel activity involved in SA node cell action potential depolarization [GO:0086041]; voltage-gated sodium channel activity [GO:0005248]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2mnra1_d4gypa2__1			Proteobacteria	Proteobacteria	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	D-glucarate catabolic process [GO:0042838]			mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d2mnra2_d2qjnd1__1			Proteobacteria	Proteobacteria	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d2moka__d3esyd___1			Proteobacteria	Cyanobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]		cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2mpah1_d1rjya1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2mpal1_d5tw5a2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2mpua__d1x5sa1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	RNA binding [GO:0003723]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; translation repressor activity [GO:0030371]; mRNA stabilization [GO:0048255]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of translation [GO:0045727]; response to cold [GO:0009409]; response to UV [GO:0009411]; stress granule assembly [GO:0034063]		mRNA stabilization [GO:0048255]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of translation [GO:0045727]; response to cold [GO:0009409]; response to UV [GO:0009411]; stress granule assembly [GO:0034063]		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	RNA binding [GO:0003723]	mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; translation repressor activity [GO:0030371]
d2mq3a1_d2nx5b___1	Metazoa	Metazoa	Chordata	Chordata	A band [GO:0031672]; C zone [GO:0014705]; cardiac myofibril [GO:0097512]; cytosol [GO:0005829]; sarcomere [GO:0030017]; striated muscle myosin thick filament [GO:0005863]; actin binding [GO:0003779]; ATPase activator activity [GO:0001671]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; myosin heavy chain binding [GO:0032036]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	A band [GO:0031672]; cardiac myofibril [GO:0097512]; cytosol [GO:0005829]; C zone [GO:0014705]; sarcomere [GO:0030017]; striated muscle myosin thick filament [GO:0005863]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	actin binding [GO:0003779]; ATPase activator activity [GO:0001671]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; myosin heavy chain binding [GO:0032036]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2mqia__d2h8ha2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome [GO:0005768]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glial cell projection [GO:0097386]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum [GO:0097038]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; Schaffer collateral - CA1 synapse [GO:0098685]; alpha-tubulin binding [GO:0043014]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; growth factor receptor binding [GO:0070851]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; axon guidance [GO:0007411]; blood coagulation [GO:0007596]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cellular response to amyloid-beta [GO:1904646]; cellular response to glycine [GO:1905430]; cellular response to L-glutamate [GO:1905232]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cytokine-mediated signaling pathway [GO:0019221]; dendrite morphogenesis [GO:0048813]; dendritic spine maintenance [GO:0097062]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ephrin receptor signaling pathway [GO:0048013]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; feeding behavior [GO:0007631]; forebrain development [GO:0030900]; heart process [GO:0003015]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide biosynthetic process [GO:0010730]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to membrane [GO:1905477]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein phosphorylation [GO:0006468]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; response to amyloid-beta [GO:1904645]; response to ethanol [GO:0045471]; response to hydrogen peroxide [GO:0042542]; response to singlet oxygen [GO:0000304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; axon guidance [GO:0007411]; blood coagulation [GO:0007596]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cellular response to amyloid-beta [GO:1904646]; cellular response to glycine [GO:1905430]; cellular response to L-glutamate [GO:1905232]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cytokine-mediated signaling pathway [GO:0019221]; dendrite morphogenesis [GO:0048813]; dendritic spine maintenance [GO:0097062]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ephrin receptor signaling pathway [GO:0048013]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; feeding behavior [GO:0007631]; forebrain development [GO:0030900]; heart process [GO:0003015]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide biosynthetic process [GO:0010730]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to membrane [GO:1905477]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein phosphorylation [GO:0006468]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; response to amyloid-beta [GO:1904645]; response to ethanol [GO:0045471]; response to hydrogen peroxide [GO:0042542]; response to singlet oxygen [GO:0000304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	actin filament [GO:0005884]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome [GO:0005768]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glial cell projection [GO:0097386]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum [GO:0097038]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; Schaffer collateral - CA1 synapse [GO:0098685]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	alpha-tubulin binding [GO:0043014]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; growth factor receptor binding [GO:0070851]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; T cell receptor binding [GO:0042608]; type 5 metabotropic glutamate receptor binding [GO:0031802]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]
d2mr3a1_d4cr2r1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytosol [GO:0005829]; nucleus [GO:0005634]; proteasome regulatory particle, lid subcomplex [GO:0008541]; proteasome storage granule [GO:0034515]; structural molecule activity [GO:0005198]; proteasome assembly [GO:0043248]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome assembly [GO:0043248]; ubiquitin-dependent protein catabolic process [GO:0006511]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]; nucleus [GO:0005634]; proteasome regulatory particle, lid subcomplex [GO:0008541]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	structural molecule activity [GO:0005198]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2mr7a1_d2avaa___1		Viridiplantae	Actinobacteria	Streptophyta	hydrolase activity, acting on ester bonds [GO:0016788]; phosphopantetheine binding [GO:0031177]; biosynthetic process [GO:0009058]	chloroplast [GO:0009507]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]		chloroplast [GO:0009507]	hydrolase activity, acting on ester bonds [GO:0016788]; phosphopantetheine binding [GO:0031177]	phosphopantetheine binding [GO:0031177]
d2mrda__d1fi5a___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	troponin complex [GO:0005861]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]
d2msja__d4ny6a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]	extracellular region [GO:0005576]			extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d2mspc__d1kiuo1__1	Metazoa		Nematoda (roundworms)	Proteobacteria	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]; identical protein binding [GO:0042802]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]	host cell membrane [GO:0033644]; pilus [GO:0009289]	identical protein binding [GO:0042802]	mannose binding [GO:0005537]
d2mssa__d1u1ra1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; identical protein binding [GO:0042802]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; response to hormone [GO:0009725]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	response to hormone [GO:0009725]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	identical protein binding [GO:0042802]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]
d2mtaa__d2b08c1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2mtac__d3hq8a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2mtac__d5dfsb___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]		apoptotic process [GO:0006915]	periplasmic space [GO:0042597]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2mtba__d1dxqd___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]
d2mtba__d4yaub1__1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]		carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d2mtpa__d1ciua1__1	Metazoa		Chordata	Firmicutes	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	carbohydrate metabolic process [GO:0005975]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	extracellular region [GO:0005576]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2mv0a__d3hpib___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d2mv2a__d3ffkd1__1	Metazoa	Metazoa	Arthropoda	Chordata	actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; actin binding [GO:0003779]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; actomyosin contractile ring assembly [GO:0000915]; axonogenesis [GO:0007409]; border follicle cell migration [GO:0007298]; cell morphogenesis [GO:0000902]; centrosome separation [GO:0051299]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; epithelial structure maintenance [GO:0010669]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; female gonad development [GO:0008585]; imaginal disc-derived leg segmentation [GO:0036011]; lamellipodium assembly [GO:0030032]; meiotic cytokinesis [GO:0033206]; mitotic cytokinesis [GO:0000281]; mushroom body development [GO:0016319]; positive regulation of protein secretion [GO:0050714]; regulation of lamellipodium assembly [GO:0010591]; rhabdomere development [GO:0042052]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; actomyosin contractile ring assembly [GO:0000915]; axonogenesis [GO:0007409]; border follicle cell migration [GO:0007298]; cell morphogenesis [GO:0000902]; centrosome separation [GO:0051299]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; epithelial structure maintenance [GO:0010669]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; female gonad development [GO:0008585]; imaginal disc-derived leg segmentation [GO:0036011]; lamellipodium assembly [GO:0030032]; meiotic cytokinesis [GO:0033206]; mitotic cytokinesis [GO:0000281]; mushroom body development [GO:0016319]; positive regulation of protein secretion [GO:0050714]; regulation of lamellipodium assembly [GO:0010591]; rhabdomere development [GO:0042052]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin binding [GO:0003779]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2my8a1_d2oj3a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of heart contraction [GO:0008016]; RNA processing [GO:0006396]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of heart contraction [GO:0008016]; RNA processing [GO:0006396]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]
d2myaa__d2uuld___1	Metazoa		Chordata		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2myna__d1z2da___1			Cyanobacteria	Firmicutes	arsenate reductase (glutaredoxin) activity [GO:0008794]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]	cytoplasm [GO:0005737]; arsenate reductase (thioredoxin) activity [GO:0030612]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]	response to arsenic-containing substance [GO:0046685]	response to arsenic-containing substance [GO:0046685]		cytoplasm [GO:0005737]	arsenate reductase (glutaredoxin) activity [GO:0008794]; protein tyrosine phosphatase activity [GO:0004725]	arsenate reductase (thioredoxin) activity [GO:0030612]; protein tyrosine phosphatase activity [GO:0004725]
d2myta__d1rxea___1			Cyanobacteria	Firmicutes	arsenate reductase (glutaredoxin) activity [GO:0008794]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]	cytoplasm [GO:0005737]; arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]	response to arsenic-containing substance [GO:0046685]	response to arsenic-containing substance [GO:0046685]		cytoplasm [GO:0005737]	arsenate reductase (glutaredoxin) activity [GO:0008794]; protein tyrosine phosphatase activity [GO:0004725]	arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]
d2mzea2_d3fuma2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2mzia2_d1mmra___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]	aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]	aging [GO:0007568]; cellular response to mechanical stimulus [GO:0071260]; collagen catabolic process [GO:0030574]; estrous cycle [GO:0044849]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; maternal process involved in female pregnancy [GO:0060135]; proteolysis [GO:0006508]; response to nutrient levels [GO:0031667]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	heparin binding [GO:0008201]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d2n18a__d5sxqb2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2n18b1_d2oz1a1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2n18c__d3o5ca1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2n23a1_d5urna1__1	Metazoa	Fungi	Chordata	Ascomycota	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter sequence-specific DNA binding [GO:0000987]; transcription regulatory region DNA binding [GO:0044212]; cellular response to peptide [GO:1901653]; erythrocyte differentiation [GO:0030218]; maternal process involved in female pregnancy [GO:0060135]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]; nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	cellular response to peptide [GO:1901653]; erythrocyte differentiation [GO:0030218]; maternal process involved in female pregnancy [GO:0060135]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter sequence-specific DNA binding [GO:0000987]; transcription regulatory region DNA binding [GO:0044212]	phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]
d2n2na__d3zylb2__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule membrane [GO:0035577]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; clathrin binding [GO:0030276]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; neutrophil degranulation [GO:0043312]; protein transport [GO:0015031]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]; 1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]; axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	endocytosis [GO:0006897]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; neutrophil degranulation [GO:0043312]; protein transport [GO:0015031]	axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	azurophil granule membrane [GO:0035577]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]	clathrin binding [GO:0030276]	1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]
d2n3uc__d2lj5a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]	protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]	protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d2n40a__d2ioud2__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; hyaluronic acid binding [GO:0005540]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; inflammatory response [GO:0006954]; negative regulation of inflammatory response [GO:0050728]; neutrophil degranulation [GO:0043312]; ovulation [GO:0030728]; positive regulation of cell migration [GO:0030335]; signal transduction [GO:0007165]	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; inflammatory response [GO:0006954]; negative regulation of inflammatory response [GO:0050728]; neutrophil degranulation [GO:0043312]; ovulation [GO:0030728]; positive regulation of cell migration [GO:0030335]; signal transduction [GO:0007165]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	virus tail, fiber [GO:0098024]	hyaluronic acid binding [GO:0005540]	
d2n45a__d1ftmb___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2n5za1_d4l41a___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	extracellular region [GO:0005576]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	hydrolase activity [GO:0016787]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d2n79c__d1kwoc___1	Metazoa	Metazoa	Chordata	Mollusca	cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]; cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; muscle filament sliding [GO:0030049]; regulation of ATPase activity [GO:0043462]; regulation of muscle contraction [GO:0006937]; regulation of muscle filament sliding speed [GO:0032972]; response to metal ion [GO:0010038]; skeletal muscle contraction [GO:0003009]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]		cardiac Troponin complex [GO:1990584]; cytosol [GO:0005829]; troponin complex [GO:0005861]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; troponin I binding [GO:0031013]; troponin T binding [GO:0031014]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]
d2n7aa1_d3pxjd2__1	Metazoa	Metazoa	Chordata	Arthropoda	integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]; cell adhesion [GO:0007155]; signal transduction [GO:0007165]	axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]	cell adhesion [GO:0007155]; signal transduction [GO:0007165]	axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]	integral component of membrane [GO:0016021]	axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]	heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d2n7ba1_d1axsa1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]; cell adhesion [GO:0007155]; signal transduction [GO:0007165]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell adhesion [GO:0007155]; signal transduction [GO:0007165]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2n7ya1_d1jk9b2__1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; protein maturation by copper ion transfer [GO:0015680]; response to copper ion [GO:0046688]; sequestering of calcium ion [GO:0051208]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; protein maturation by copper ion transfer [GO:0015680]; response to copper ion [GO:0046688]; sequestering of calcium ion [GO:0051208]	age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	cell [GO:0005623]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]
d2n80a__d1ygoa2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d2n80b__d2bq9c2__1	Metazoa		Chordata		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]		negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]		GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]	
d2n9ga__d5pg9a1__1		Metazoa		Chordata	nucleus [GO:0005634]; histone binding [GO:0042393]; chromatin remodeling [GO:0006338]; histone modification [GO:0016570]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	chromatin remodeling [GO:0006338]; histone modification [GO:0016570]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleus [GO:0005634]	nucleus [GO:0005634]	histone binding [GO:0042393]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d2n9ua1_d3nhzb___1			Proteobacteria	Actinobacteria	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; growth of symbiont in host [GO:0044117]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]	phosphorelay signal transduction system [GO:0000160]	growth of symbiont in host [GO:0044117]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]		cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]		DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2na0a__d1nx2a___1	Metazoa	Metazoa	Chordata	Chordata	membrane [GO:0016020]; photoreceptor outer segment [GO:0001750]; calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048]; guanylate cyclase regulator activity [GO:0030249]; cellular response to calcium ion [GO:0071277]; phototransduction [GO:0007602]; positive regulation of guanylate cyclase activity [GO:0031284]; regulation of guanylate cyclase activity [GO:0031282]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; proteolysis [GO:0006508]	cellular response to calcium ion [GO:0071277]; phototransduction [GO:0007602]; positive regulation of guanylate cyclase activity [GO:0031284]; regulation of guanylate cyclase activity [GO:0031282]; visual perception [GO:0007601]	proteolysis [GO:0006508]	membrane [GO:0016020]; photoreceptor outer segment [GO:0001750]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048]; guanylate cyclase regulator activity [GO:0030249]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d2nada1_d2p9cb1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; formate dehydrogenase (NAD+) activity [GO:0008863]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; formate catabolic process [GO:0042183]	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	formate catabolic process [GO:0042183]	L-serine biosynthetic process [GO:0006564]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	formate dehydrogenase (NAD+) activity [GO:0008863]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]
d2nafa__d4p7bc___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	cytoplasm [GO:0005737]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA hydrolase activity [GO:0004045]	aminoacyl-tRNA hydrolase activity [GO:0004045]
d2napa2_d3iasl3__1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	plasma membrane [GO:0005886]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]	quinone binding [GO:0048038]
d2nbua__d3wwqj___1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleotide-excision repair factor 2 complex [GO:0000111]; proteasome complex [GO:0000502]; damaged DNA binding [GO:0003684]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deglycosylation [GO:0006517]; ubiquitin-dependent ERAD pathway [GO:0030433]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deglycosylation [GO:0006517]; ubiquitin-dependent ERAD pathway [GO:0030433]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleotide-excision repair factor 2 complex [GO:0000111]; proteasome complex [GO:0000502]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2nbwb__d5go0a___1	Fungi		Ascomycota		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleotide-excision repair factor 2 complex [GO:0000111]; proteasome complex [GO:0000502]; damaged DNA binding [GO:0003684]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deglycosylation [GO:0006517]; ubiquitin-dependent ERAD pathway [GO:0030433]	cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deglycosylation [GO:0006517]; ubiquitin-dependent ERAD pathway [GO:0030433]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleotide-excision repair factor 2 complex [GO:0000111]; proteasome complex [GO:0000502]	cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2nckl__d4di6e1__1			Proteobacteria	Spirochaetes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2ncna1_d2rsua___1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; microtubule [GO:0005874]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; microtubule [GO:0005874]; organelle membrane [GO:0031090]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]	protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d2ndpa__d1hueb___1			Tenericutes	Firmicutes	DNA binding [GO:0003677]	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]		chromosome condensation [GO:0030261]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2ndpa__d4qjnd___1			Tenericutes	Firmicutes	DNA binding [GO:0003677]	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]		chromosome condensation [GO:0030261]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2ng1a2_d2afig___1			Deinococcus-Thermus	Proteobacteria	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	nitrogen fixation [GO:0009399]	signal recognition particle [GO:0048500]	molybdenum-iron nitrogenase complex [GO:0016612]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2ng1a2_d4a82b2__1			Deinococcus-Thermus	Firmicutes	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]		signal recognition particle [GO:0048500]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]
d2ngra__d3ihwa1__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cell periphery [GO:0071944]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]; GTP binding [GO:0005525]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; polyubiquitin modification-dependent protein binding [GO:0031593]; cellular response to reactive oxygen species [GO:0034614]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; signal transduction [GO:0007165]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cellular response to reactive oxygen species [GO:0034614]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; signal transduction [GO:0007165]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	cell periphery [GO:0071944]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; polyubiquitin modification-dependent protein binding [GO:0031593]
d2nipb__d3hu2b3__1		Metazoa	Proteobacteria	Chordata	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	nitrogen fixation [GO:0009399]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	molybdenum-iron nitrogenase complex [GO:0016612]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d2nipb__d4jycc___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	GTP binding [GO:0005525]; GTPase activity [GO:0003924]	nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d2nlja2_d1za6b3__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2nlja2_d5m63l1__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2nljb1_d5ihul1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2nljb2_d1uwgl2__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2nljb2_d3bt2h1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; invadopodium membrane [GO:0071438]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; urokinase plasminogen activator receptor activity [GO:0030377]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]		blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]	voltage-gated potassium channel complex [GO:0008076]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; invadopodium membrane [GO:0071438]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; urokinase plasminogen activator receptor activity [GO:0030377]
d2nlna__d1b8la___1	Metazoa	Metazoa	Chordata	Chordata	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; supramolecular fiber [GO:0099512]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cochlea development [GO:0090102]; positive regulation of axon extension involved in regeneration [GO:0048691]; positive regulation of optical nerve axon regeneration [GO:1905593]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]; response to wounding [GO:0009611]	calcium ion binding [GO:0005509]	cochlea development [GO:0090102]; positive regulation of axon extension involved in regeneration [GO:0048691]; positive regulation of optical nerve axon regeneration [GO:1905593]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]; response to wounding [GO:0009611]		cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; supramolecular fiber [GO:0099512]; vesicle [GO:0031982]		calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]
d2nm1a1_d2du1b___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	carbohydrate binding [GO:0030246]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]		lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	carbohydrate binding [GO:0030246]
d2nm2a__d2yzec1__1			Firmicutes	Actinobacteria	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]			dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]	urate oxidase activity [GO:0004846]
d2nm2b__d1sqll___1		Viridiplantae	Firmicutes	Streptophyta	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]	dihydroneopterin aldolase activity [GO:0004150]
d2nm2d__d1sqlf___1		Viridiplantae	Firmicutes	Streptophyta	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]	dihydroneopterin aldolase activity [GO:0004150]
d2nm3a__d1sqlo___1		Viridiplantae	Firmicutes	Streptophyta	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]	dihydroneopterin aldolase activity [GO:0004150]
d2nmba__d2rozb1__1	Metazoa	Metazoa	Arthropoda	Chordata	basal part of cell [GO:0045178]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; Notch binding [GO:0005112]; asymmetric neuroblast division [GO:0055059]; cell fate commitment [GO:0045165]; cellular protein localization [GO:0034613]; central nervous system development [GO:0007417]; centrosome localization [GO:0051642]; embryonic heart tube development [GO:0035050]; enteroendocrine cell differentiation [GO:0035883]; glial cell migration [GO:0008347]; heart development [GO:0007507]; Malpighian tubule tip cell differentiation [GO:0061382]; muscle cell fate specification [GO:0042694]; negative regulation of gene expression [GO:0010629]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of receptor recycling [GO:0001920]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; pericardial nephrocyte differentiation [GO:0061320]; positive regulation of endocytosis [GO:0045807]; protein localization [GO:0008104]; regulation of asymmetric cell division [GO:0009786]; regulation of nervous system development [GO:0051960]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; rhythmic behavior [GO:0007622]; sensory organ precursor cell division [GO:0045035]; sensory organ precursor cell fate determination [GO:0016360]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; amyloid-beta binding [GO:0001540]; histone acetyltransferase binding [GO:0035035]; transcription factor binding [GO:0008134]; actin filament-based movement [GO:0030048]; axon guidance [GO:0007411]; cell cycle arrest [GO:0007050]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; neuron migration [GO:0001764]; positive regulation of apoptotic process [GO:0043065]; protein stabilization [GO:0050821]; regulation of transcription, DNA-templated [GO:0006355]	asymmetric neuroblast division [GO:0055059]; cell fate commitment [GO:0045165]; cellular protein localization [GO:0034613]; central nervous system development [GO:0007417]; centrosome localization [GO:0051642]; embryonic heart tube development [GO:0035050]; enteroendocrine cell differentiation [GO:0035883]; glial cell migration [GO:0008347]; heart development [GO:0007507]; Malpighian tubule tip cell differentiation [GO:0061382]; muscle cell fate specification [GO:0042694]; negative regulation of gene expression [GO:0010629]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of receptor recycling [GO:0001920]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; pericardial nephrocyte differentiation [GO:0061320]; positive regulation of endocytosis [GO:0045807]; protein localization [GO:0008104]; regulation of asymmetric cell division [GO:0009786]; regulation of nervous system development [GO:0051960]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; rhythmic behavior [GO:0007622]; sensory organ precursor cell division [GO:0045035]; sensory organ precursor cell fate determination [GO:0016360]	actin filament-based movement [GO:0030048]; axon guidance [GO:0007411]; cell cycle arrest [GO:0007050]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; neuron migration [GO:0001764]; positive regulation of apoptotic process [GO:0043065]; protein stabilization [GO:0050821]; regulation of transcription, DNA-templated [GO:0006355]	basal part of cell [GO:0045178]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; Notch binding [GO:0005112]	amyloid-beta binding [GO:0001540]; histone acetyltransferase binding [GO:0035035]; transcription factor binding [GO:0008134]
d2nmna__d4gkxf___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; sarcomere [GO:0030017]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; blood coagulation [GO:0007596]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; negative regulation of protein targeting to mitochondrion [GO:1903215]; positive regulation of organelle organization [GO:0010638]; protein folding [GO:0006457]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	blood coagulation [GO:0007596]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; negative regulation of protein targeting to mitochondrion [GO:1903215]; positive regulation of organelle organization [GO:0010638]; protein folding [GO:0006457]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; sarcomere [GO:0030017]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d2nmsa1_d4jn2a1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ceramide binding [GO:0097001]; interleukin-4 receptor binding [GO:0005136]; phosphatidylserine binding [GO:0001786]; interleukin-13-mediated signaling pathway [GO:0035772]; negative regulation of apoptotic cell clearance [GO:2000426]; negative regulation of mast cell activation [GO:0033004]; negative regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034125]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; regulation of immune response [GO:0050776]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]		interleukin-13-mediated signaling pathway [GO:0035772]; negative regulation of apoptotic cell clearance [GO:2000426]; negative regulation of mast cell activation [GO:0033004]; negative regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034125]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; regulation of immune response [GO:0050776]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		ceramide binding [GO:0097001]; interleukin-4 receptor binding [GO:0005136]; phosphatidylserine binding [GO:0001786]	
d2nmyb__d3fv3h___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2nn6c2_d2br2f2__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; RNA binding [GO:0003723]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; regulation of mRNA stability [GO:0043488]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA processing [GO:0006364]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; regulation of mRNA stability [GO:0043488]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA processing [GO:0006364]	rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytoplasmic exosome (RNase complex) [GO:0000177]	RNA binding [GO:0003723]	3'-5'-exoribonuclease activity [GO:0000175]
d2nn6g1_d3e9ib1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; RNA binding [GO:0003723]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; regulation of mRNA stability [GO:0043488]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA processing [GO:0006364]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; regulation of mRNA stability [GO:0043488]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA processing [GO:0006364]	lysyl-tRNA aminoacylation [GO:0006430]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	RNA binding [GO:0003723]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d2nn7a__d5dska___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2nn7b__d4uovc___1	Metazoa		Chordata	Aquificae	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2nnhb__d3weca___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]		arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2nnhb__d5b2va___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d2nnja__d5frba1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; cellular response to drug [GO:0035690]; ergosterol biosynthetic process [GO:0006696]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cellular response to drug [GO:0035690]; ergosterol biosynthetic process [GO:0006696]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]	drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d2nnpa__d3gi6a___1					aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2nnpa__d5p5na___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]
d2nnpb__d5p4ba___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]
d2nnua2_d1tueg___1	Metazoa		Chordata		chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	host cell nucleus [GO:0042025]; host cytoskeleton [GO:0044163]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]; viral DNA genome replication [GO:0039693]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	host cell nucleus [GO:0042025]; host cytoskeleton [GO:0044163]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nucleotide binding [GO:0000166]
d2nnxd__d1hl5a___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d2nnya__d3wtwc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]
d2nnya__d4i09a2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d2no0a__d3oe7v2__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; deoxycytidine kinase activity [GO:0004137]; deoxynucleoside kinase activity [GO:0019136]; drug binding [GO:0008144]; protein homodimerization activity [GO:0042803]; purine-containing compound salvage [GO:0043101]; pyrimidine nucleoside salvage [GO:0043097]; pyrimidine nucleotide metabolic process [GO:0006220]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	purine-containing compound salvage [GO:0043101]; pyrimidine nucleoside salvage [GO:0043097]; pyrimidine nucleotide metabolic process [GO:0006220]	ATP synthesis coupled proton transport [GO:0015986]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; deoxycytidine kinase activity [GO:0004137]; deoxynucleoside kinase activity [GO:0019136]; drug binding [GO:0008144]; protein homodimerization activity [GO:0042803]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2no4a1_d5ai5a1__1		Metazoa	Proteobacteria	Chordata	(S)-2-haloacid dehalogenase activity [GO:0018784]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	(S)-2-haloacid dehalogenase activity [GO:0018784]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2no8a__d4qkoc___1			Proteobacteria	Proteobacteria	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	bacteriocin immunity [GO:0030153]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]			toxic substance binding [GO:0015643]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]
d2noea1_d1kqja___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]
d2noea1_d3cwab1__1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d2nofa1_d2ofkb___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]
d2noha1_d1fn7a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]
d2noha1_d1p7ma___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]
d2noia2_d3d4vd1__1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d2noia2_d4ai5c___1	Metazoa		Chordata		mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]		acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]		mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	
d2nola1_d4ai5e1__1	Metazoa		Chordata		mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]		acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]		mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	
d2noxn__d3e08c___1			Proteobacteria	Proteobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; tryptophan 2,3-dioxygenase activity [GO:0004833]; NAD biosynthetic process [GO:0009435]; protein homooligomerization [GO:0051260]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process to kynurenine [GO:0019441]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; tryptophan 2,3-dioxygenase activity [GO:0004833]; protein homotetramerization [GO:0051289]; tryptophan catabolic process to acetyl-CoA [GO:0019442]; tryptophan catabolic process to kynurenine [GO:0019441]	NAD biosynthetic process [GO:0009435]; protein homooligomerization [GO:0051260]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process to kynurenine [GO:0019441]	protein homotetramerization [GO:0051289]; tryptophan catabolic process to acetyl-CoA [GO:0019442]; tryptophan catabolic process to kynurenine [GO:0019441]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; tryptophan 2,3-dioxygenase activity [GO:0004833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; tryptophan 2,3-dioxygenase activity [GO:0004833]
d2np1b__d3wvma___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	vasodilation [GO:0042311]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]
d2np2b__d1huub___1			Spirochaetes	Firmicutes	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]	DNA binding [GO:0003677]; chromosome condensation [GO:0030261]	chromosome condensation [GO:0030261]	chromosome condensation [GO:0030261]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2np6a1_d5gp1c___1			Deinococcus-Thermus		DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA restriction-modification system [GO:0009307]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2np6a2_d1yf2b1__1			Deinococcus-Thermus	Euryarchaeota	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]	DNA binding [GO:0003677]
d2npaa__d5c4sa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d2npfb1_d2bv3a1__1	Fungi		Ascomycota	Deinococcus-Thermus	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]	maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	translational elongation [GO:0006414]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]	GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]
d2npfb4_d1ktva4__1	Fungi		Ascomycota	Deinococcus-Thermus	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity, coupled [GO:0061745]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translational elongation [GO:0006414]	maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	translational elongation [GO:0006414]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]	GDP binding [GO:0019003]; GTPase activity, coupled [GO:0061745]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]
d2nppc1_d3lh7a___1	Metazoa		Chordata		chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]		apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]		chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]		GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]	
d2nppf1_d3d03a___1	Metazoa		Chordata	Proteobacteria	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]		chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]		GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2nptd__d1f2ri___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; spindle [GO:0005819]; ATP binding [GO:0005524]; MAP kinase kinase activity [GO:0004708]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; activation of MAPK activity [GO:0000187]; activation of protein kinase activity [GO:0032147]; cellular response to growth factor stimulus [GO:0071363]; cellular response to laminar fluid shear stress [GO:0071499]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000342]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription by RNA polymerase II [GO:0045944]; signal transduction [GO:0007165]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; deoxyribonuclease activity [GO:0004536]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclease activity [GO:0004518]; protein domain specific binding [GO:0019904]; apoptotic chromosome condensation [GO:0030263]; apoptotic DNA fragmentation [GO:0006309]; DNA catabolic process [GO:0006308]; protein homooligomerization [GO:0051260]	activation of MAPK activity [GO:0000187]; activation of protein kinase activity [GO:0032147]; cellular response to growth factor stimulus [GO:0071363]; cellular response to laminar fluid shear stress [GO:0071499]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000342]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription by RNA polymerase II [GO:0045944]; signal transduction [GO:0007165]; signal transduction by protein phosphorylation [GO:0023014]	apoptotic chromosome condensation [GO:0030263]; apoptotic DNA fragmentation [GO:0006309]; DNA catabolic process [GO:0006308]; protein homooligomerization [GO:0051260]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; spindle [GO:0005819]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; MAP kinase kinase activity [GO:0004708]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]	deoxyribonuclease activity [GO:0004536]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclease activity [GO:0004518]; protein domain specific binding [GO:0019904]
d2nq2c__d2zs8a___1			Proteobacteria	Actinobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]		coenzyme A biosynthetic process [GO:0015937]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d2nq9a__d2nqjb___1			Proteobacteria	Proteobacteria	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]			deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]
d2nqbd__d1m18b___1	Metazoa	Metazoa	Arthropoda	Chordata	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; DNA-templated transcription, initiation [GO:0006352]	chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	DNA-templated transcription, initiation [GO:0006352]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]	nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2nqbe__d3azeh___1	Metazoa	Metazoa	Arthropoda	Chordata	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2nqbf__d3aznf___1	Metazoa	Metazoa	Arthropoda	Chordata	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2nqca__d2eeda1__1	Metazoa	Metazoa	Chordata	Chordata	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d2nqda__d2h7wa1__1					cell surface [GO:0009986]; ciliary pocket [GO:0020016]; cytoplasmic vesicle [GO:0031410]; cysteine-type endopeptidase inhibitor activity [GO:0004869]	cell surface [GO:0009986]; ciliary pocket [GO:0020016]; cytoplasmic vesicle [GO:0031410]; cysteine-type endopeptidase inhibitor activity [GO:0004869]			cell surface [GO:0009986]; ciliary pocket [GO:0020016]; cytoplasmic vesicle [GO:0031410]	cell surface [GO:0009986]; ciliary pocket [GO:0020016]; cytoplasmic vesicle [GO:0031410]	cysteine-type endopeptidase inhibitor activity [GO:0004869]	cysteine-type endopeptidase inhibitor activity [GO:0004869]
d2nqja__d3qzaa___1			Proteobacteria	Actinobacteria	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	D-xylose metabolic process [GO:0042732]		cytoplasm [GO:0005737]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d2nqjb__d4hhmh___1			Proteobacteria	Actinobacteria	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	D-xylose metabolic process [GO:0042732]		cytoplasm [GO:0005737]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d2nqkb3_d1o8ob___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; auxin-activated signaling pathway [GO:0009734]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; response to metal ion [GO:0010038]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	auxin-activated signaling pathway [GO:0009734]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	ATP binding [GO:0005524]; molybdenum ion binding [GO:0030151]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]
d2nqmb2_d1g8la2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d2nqnb2_d2nrpb2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d2nqnb3_d2nqua3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d2nqo.1_d5lf4o___1		Metazoa	Proteobacteria	Chordata	glutathione hydrolase activity [GO:0036374]; glutathione catabolic process [GO:0006751]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of interleukin-8 production [GO:0032757]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	glutathione catabolic process [GO:0006751]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of interleukin-8 production [GO:0032757]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	glutathione hydrolase activity [GO:0036374]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2nqpb1_d2ab4a2__1			Proteobacteria	Thermotogae	pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]; tRNA pseudouridine synthesis [GO:0031119]	mitochondrion [GO:0005739]; pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]; mRNA pseudouridine synthesis [GO:1990481]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]	tRNA pseudouridine synthesis [GO:0031119]	mRNA pseudouridine synthesis [GO:1990481]; tRNA modification [GO:0006400]; tRNA pseudouridine synthesis [GO:0031119]		mitochondrion [GO:0005739]	pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]	pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; tRNA pseudouridine synthase activity [GO:0106029]
d2nqpd1_d1v9fa___1			Proteobacteria	Proteobacteria	pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]; tRNA pseudouridine synthesis [GO:0031119]	cytosol [GO:0005829]; pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; rRNA pseudouridine synthase activity [GO:0120159]; enzyme-directed rRNA pseudouridine synthesis [GO:0000455]; ribosomal large subunit assembly [GO:0000027]	tRNA pseudouridine synthesis [GO:0031119]	enzyme-directed rRNA pseudouridine synthesis [GO:0000455]; ribosomal large subunit assembly [GO:0000027]		cytosol [GO:0005829]	pseudouridine synthase activity [GO:0009982]; tRNA binding [GO:0000049]; tRNA pseudouridine synthase activity [GO:0106029]	pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; rRNA pseudouridine synthase activity [GO:0120159]
d2nqqa1_d1wu2b1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	molybdopterin cofactor biosynthetic process [GO:0032324]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdopterin cofactor biosynthetic process [GO:0032324]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	
d2nqsb2_d5erua1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]
d2nqub2_d5ersa1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]
d2nqub3_d4twgc___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]		molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	
d2nqva3_d2qq1f___1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	
d2nqvb3_d4twgd___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]		molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	
d2nr6c2_d4xbpd2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2nrac2_d5u7bb1__1			Proteobacteria	Proteobacteria	DNA-directed DNA polymerase activity [GO:0003887]; DNA replication initiation [GO:0006270]	alkylmercury lyase activity [GO:0018836]; organomercury catabolic process [GO:0046413]; response to mercury ion [GO:0046689]	DNA replication initiation [GO:0006270]	organomercury catabolic process [GO:0046413]; response to mercury ion [GO:0046689]			DNA-directed DNA polymerase activity [GO:0003887]	alkylmercury lyase activity [GO:0018836]
d2nrbd2_d1ooyb1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]
d2nrca2_d4eu6a1__1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	mitochondrion [GO:0005739]		3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d2nrda1_d1jzja___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2nrob2_d2nqna2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d2nrob3_d2nrsb3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d2nrpa2_d2nqqc2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d2nrpb1_d1g8ra1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d2nrsa1_d2nrob1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d2nrsa2_d5erqa1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]
d2nrsb3_d2qq1d___1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]	
d2ns1b1_d2zomb___1		Viridiplantae	Proteobacteria	Streptophyta	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; ammonium transmembrane transporter activity [GO:0008519]; identical protein binding [GO:0042802]; uniporter activity [GO:0015292]; ammonium transport [GO:0015696]; carbon dioxide transport [GO:0015670]; nitrogen utilization [GO:0019740]	chloroplast [GO:0009507]; copper ion binding [GO:0005507]; protein homotrimerization [GO:0070207]; response to metal ion [GO:0010038]	ammonium transport [GO:0015696]; carbon dioxide transport [GO:0015670]; nitrogen utilization [GO:0019740]	protein homotrimerization [GO:0070207]; response to metal ion [GO:0010038]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	chloroplast [GO:0009507]	ammonium transmembrane transporter activity [GO:0008519]; identical protein binding [GO:0042802]; uniporter activity [GO:0015292]	copper ion binding [GO:0005507]
d2ns7d1_d3btla1__1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2nsga1_d2nsfa1__1			Actinobacteria	Actinobacteria	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2nsla__d4ay4d___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; identical protein binding [GO:0042802]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]		5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; identical protein binding [GO:0042802]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]
d2nssa__d1jf4a___1	Metazoa	Metazoa	Chordata	Annelida	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2nsxa2_d1u2ya2__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d2nsza1_d4fyra4__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; BMP signaling pathway [GO:0030509]; cell aging [GO:0007569]; cellular response to lipopolysaccharide [GO:0071222]; epithelial to mesenchymal transition involved in cardiac fibroblast development [GO:0060940]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of inflammatory response [GO:0050729]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; regulation of protein metabolic process [GO:0051246]	cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	apoptotic process [GO:0006915]; BMP signaling pathway [GO:0030509]; cell aging [GO:0007569]; cellular response to lipopolysaccharide [GO:0071222]; epithelial to mesenchymal transition involved in cardiac fibroblast development [GO:0060940]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of inflammatory response [GO:0050729]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; regulation of protein metabolic process [GO:0051246]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	RNA binding [GO:0003723]	aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d2nt0a2_d3igua1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d2nt0b2_d3e1f23__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	beta-galactosidase complex [GO:0009341]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2nt0c2_d1jz0d5__1	Metazoa		Chordata		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	
d2nt1b2_d1deda4__1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	extracellular region [GO:0005576]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2nt1c2_d1ukqa4__1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	extracellular region [GO:0005576]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2nt1d2_d1ur0b___1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	metabolic process [GO:0008152]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]
d2nt2b__d5bzzd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular space [GO:0005615]; actin binding [GO:0003779]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; actin cytoskeleton organization [GO:0030036]; cell morphogenesis [GO:0000902]; protein dephosphorylation [GO:0006470]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; ubiquitin-specific protease binding [GO:1990381]; adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	actin cytoskeleton organization [GO:0030036]; cell morphogenesis [GO:0000902]; protein dephosphorylation [GO:0006470]	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	actin binding [GO:0003779]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381]
d2nt2c__d1fpzd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular space [GO:0005615]; actin binding [GO:0003779]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; actin cytoskeleton organization [GO:0030036]; cell morphogenesis [GO:0000902]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cell cycle arrest [GO:0007050]; cilium assembly [GO:0060271]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell population proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	actin cytoskeleton organization [GO:0030036]; cell morphogenesis [GO:0000902]; protein dephosphorylation [GO:0006470]	cell cycle arrest [GO:0007050]; cilium assembly [GO:0060271]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell population proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]	actin binding [GO:0003779]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d2nt6b__d2qx3a___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; lyase activity [GO:0016829]; polysaccharide catabolic process [GO:0000272]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]	lyase activity [GO:0016829]
d2nt7a__d5k24a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; transmembrane transporter activity [GO:0022857]; ion transport [GO:0006811]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	ion transport [GO:0006811]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	transmembrane transporter activity [GO:0022857]
d2ntaa__d2cmaa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2ntaa__d3d1oa___1	Metazoa		Chordata	Firmicutes	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	protein tyrosine phosphatase activity [GO:0004725]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]		cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]		cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	protein tyrosine phosphatase activity [GO:0004725]
d2ntca__d1ksya___1					host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA replication [GO:0006260]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]	host cell nucleus [GO:0042025]	host cell nucleus [GO:0042025]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]
d2ntdc__d3hbwa___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; filopodium [GO:0030175]; growth cone [GO:0030426]; intercalated disc [GO:0014704]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; beta-tubulin binding [GO:0048487]; growth factor activity [GO:0008083]; ion channel binding [GO:0044325]; microtubule binding [GO:0008017]; protein kinase activator activity [GO:0030295]; sodium channel regulator activity [GO:0017080]; cell-cell signaling [GO:0007267]; cerebral cortex cell migration [GO:0021795]; establishment of neuroblast polarity [GO:0045200]; hippocampus development [GO:0021766]; learning [GO:0007612]; MAPK cascade [GO:0000165]; memory [GO:0007613]; microtubule polymerization [GO:0046785]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; protein localization to plasma membrane [GO:0072659]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; signal transduction [GO:0007165]; sodium ion transport [GO:0006814]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell-cell signaling [GO:0007267]; cerebral cortex cell migration [GO:0021795]; establishment of neuroblast polarity [GO:0045200]; hippocampus development [GO:0021766]; learning [GO:0007612]; MAPK cascade [GO:0000165]; memory [GO:0007613]; microtubule polymerization [GO:0046785]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; protein localization to plasma membrane [GO:0072659]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; signal transduction [GO:0007165]; sodium ion transport [GO:0006814]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; filopodium [GO:0030175]; growth cone [GO:0030426]; intercalated disc [GO:0014704]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	beta-tubulin binding [GO:0048487]; growth factor activity [GO:0008083]; ion channel binding [GO:0044325]; microtubule binding [GO:0008017]; protein kinase activator activity [GO:0030295]; sodium channel regulator activity [GO:0017080]
d2ntdc__d3wo2c___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d2ntfa1_d5vxjf___1	Metazoa		Chordata	Proteobacteria		extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]		
d2ntfa2_d3cfjh2__1	Metazoa	Metazoa	Chordata	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ntib1_d2polb1__1			Crenarchaeota	Proteobacteria	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	PCNA complex [GO:0043626]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d2ntic1_d1b77c1__1			Crenarchaeota		PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	PCNA complex [GO:0043626]		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	
d2ntic2_d1u76e1__1		Metazoa	Crenarchaeota	Chordata	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	PCNA complex [GO:0043626]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d2ntic2_d2ijxa2__1			Crenarchaeota	Crenarchaeota	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	PCNA complex [GO:0043626]	PCNA complex [GO:0043626]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d2ntif2_d3gpna2__1		Fungi	Crenarchaeota	Ascomycota	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	PCNA complex [GO:0043626]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]
d2ntih2_d3qsbb1__1			Crenarchaeota	Proteobacteria	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	PCNA complex [GO:0043626]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d2ntjb__d1nfqb___1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	plasma membrane [GO:0005886]; androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; C21-steroid hormone metabolic process [GO:0008207]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	C21-steroid hormone metabolic process [GO:0008207]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	plasma membrane [GO:0005886]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d2ntoa1_d19gsa2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2ntoa2_d5ecmf2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]		glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	glutathione transferase activity [GO:0004364]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2ntpa__d2nspa___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]
d2ntqa__d2iq7d___1		Fungi	Proteobacteria	Ascomycota	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]	polygalacturonase activity [GO:0004650]
d2ntqa__d2nspb___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]
d2ntqb__d1wmra2__1		Fungi	Proteobacteria	Ascomycota	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; isopullulanase activity [GO:0051675]; metabolic process [GO:0008152]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	metabolic process [GO:0008152]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]	isopullulanase activity [GO:0051675]
d2ntqb__d2nstb___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]
d2ntsa2_d4o1ne2__1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; peptidase activity [GO:0008233]; pathogenesis [GO:0009405]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	peptidase activity [GO:0008233]
d2ntta1_d1ptok___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	metal ion binding [GO:0046872]	toxin activity [GO:0090729]
d2ntvb__d5bshh1__1		Viridiplantae	Actinobacteria	Streptophyta	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid biosynthetic process [GO:0006633]	cell wall [GO:0005618]; nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]; L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]	fatty acid biosynthetic process [GO:0006633]	L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]		cell wall [GO:0005618]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]	nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d2nu3e__d3zv8a1__1			Actinobacteria		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2nu4e__d1o3ha___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2nu5b__d1vboa___1		Viridiplantae	Rhodophyta	Streptophyta	cell [GO:0005623]; carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]	carbohydrate binding [GO:0030246]			cell [GO:0005623]		carbohydrate binding [GO:0030246]; glucose binding [GO:0005536]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; N-acetylgalactosamine binding [GO:0046871]	carbohydrate binding [GO:0030246]
d2nu6b2_d1bxrc6__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2nu6d1_d3qwia___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]		cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2nu7d2_d3ufxf2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]		cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]
d2nu8a1_d1ht0a2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d2nu8d1_d4fccg2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]		cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d2nu8d2_d2nu9i1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d2nu8e2_d2yw2a2__1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]		cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d2nu9a1_d3etdb2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d2nu9e2_d1kc7a3__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	pyruvate metabolic process [GO:0006090]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]		cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]
d2nuba4_d4jk8b___1		Metazoa	Aquificae	Chordata	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	catalytic step 2 spliceosome [GO:0071013]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal tri-snRNP complex assembly [GO:0000244]		cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal tri-snRNP complex assembly [GO:0000244]		catalytic step 2 spliceosome [GO:0071013]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]
d2nuuk__d3gsdd___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; ammonium transmembrane transporter activity [GO:0008519]; identical protein binding [GO:0042802]; uniporter activity [GO:0015292]; ammonium transport [GO:0015696]; carbon dioxide transport [GO:0015670]; nitrogen utilization [GO:0019740]	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; response to metal ion [GO:0010038]	ammonium transport [GO:0015696]; carbon dioxide transport [GO:0015670]; nitrogen utilization [GO:0019740]	response to metal ion [GO:0010038]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ammonium transmembrane transporter activity [GO:0008519]; identical protein binding [GO:0042802]; uniporter activity [GO:0015292]	copper ion binding [GO:0005507]
d2nuxb__d1i2pb___1			Crenarchaeota	Proteobacteria	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; membrane [GO:0016020]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		cytosol [GO:0005829]; membrane [GO:0016020]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]
d2nuyb__d3i7sa___1			Crenarchaeota	Proteobacteria	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytosol [GO:0005829]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]
d2nv2d__d3zr4d___1			Firmicutes	Thermotogae	cytosol [GO:0005829]; glutaminase complex [GO:1903600]; glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	cytoplasm [GO:0005737]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; histidine biosynthetic process [GO:0000105]	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	histidine biosynthetic process [GO:0000105]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]	cytoplasm [GO:0005737]	glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]
d2nv2f__d4l8fa___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; glutaminase complex [GO:1903600]; glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	vacuole [GO:0005773]; gamma-glutamyl-peptidase activity [GO:0034722]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]	vacuole [GO:0005773]	glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	gamma-glutamyl-peptidase activity [GO:0034722]
d2nv2j__d1k9vf___1			Firmicutes	Thermotogae	cytosol [GO:0005829]; glutaminase complex [GO:1903600]; glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	cytoplasm [GO:0005737]; glutaminase activity [GO:0004359]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; glutamine metabolic process [GO:0006541]; histidine biosynthetic process [GO:0000105]	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	glutamine metabolic process [GO:0006541]; histidine biosynthetic process [GO:0000105]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]	cytoplasm [GO:0005737]	glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	glutaminase activity [GO:0004359]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]
d2nv2p__d1ce8d2__1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; glutaminase complex [GO:1903600]; glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2nv2u__d2zbtb___1			Firmicutes	Deinococcus-Thermus	cytosol [GO:0005829]; glutaminase complex [GO:1903600]; glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; pyridoxal phosphate biosynthetic process [GO:0042823]	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	pyridoxal phosphate biosynthetic process [GO:0042823]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]		glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d2nv3a__d2h3za___1					virion [GO:0019012]; structural molecule activity [GO:0005198]; viral process [GO:0016032]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral process [GO:0016032]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	virion [GO:0019012]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	structural molecule activity [GO:0005198]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2nv5a__d1f5da___1	Metazoa		Chordata		axon [GO:0030424]; cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]		negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]		axon [GO:0030424]; cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]		chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]	
d2nv5a__d1wrma1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; leading edge of lamellipodium [GO:0061851]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cellular response to epidermal growth factor stimulus [GO:0071364]; negative regulation of cell migration [GO:0030336]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903996]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of JNK cascade [GO:0046330]; regulation of cell population proliferation [GO:0042127]; transforming growth factor beta receptor signaling pathway [GO:0007179]	negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]	cellular response to epidermal growth factor stimulus [GO:0071364]; negative regulation of cell migration [GO:0030336]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903996]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of JNK cascade [GO:0046330]; regulation of cell population proliferation [GO:0042127]; transforming growth factor beta receptor signaling pathway [GO:0007179]	axon [GO:0030424]; cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; leading edge of lamellipodium [GO:0061851]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]	non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]
d2nv5b__d5bugc1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; ubiquitin-specific protease binding [GO:1990381]; adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	axon [GO:0030424]; cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]	anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381]
d2nv5c__d4yr8b___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]	axon [GO:0030424]; basal dendrite [GO:0097441]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; JUN kinase activity [GO:0004705]; kinase activity [GO:0016301]; MAP kinase activity [GO:0004707]; protein serine/threonine kinase activity [GO:0004674]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; JUN phosphorylation [GO:0007258]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein binding [GO:0032091]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cyclase activity [GO:0031281]; positive regulation of deacetylase activity [GO:0090045]; positive regulation of gene expression [GO:0010628]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein metabolic process [GO:0051247]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of DNA replication origin binding [GO:1902595]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of gene expression [GO:0010468]; regulation of macroautophagy [GO:0016241]; regulation of protein localization [GO:0032880]; response to UV [GO:0009411]; rhythmic process [GO:0048511]; stress-activated MAPK cascade [GO:0051403]	negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]	cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; JUN phosphorylation [GO:0007258]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein binding [GO:0032091]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cyclase activity [GO:0031281]; positive regulation of deacetylase activity [GO:0090045]; positive regulation of gene expression [GO:0010628]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein metabolic process [GO:0051247]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of DNA replication origin binding [GO:1902595]; regulation of gene expression [GO:0010468]; regulation of macroautophagy [GO:0016241]; regulation of protein localization [GO:0032880]; response to UV [GO:0009411]; rhythmic process [GO:0048511]; stress-activated MAPK cascade [GO:0051403]	axon [GO:0030424]; cell junction [GO:0030054]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]	axon [GO:0030424]; basal dendrite [GO:0097441]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]	ATP binding [GO:0005524]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; JUN kinase activity [GO:0004705]; kinase activity [GO:0016301]; MAP kinase activity [GO:0004707]; protein serine/threonine kinase activity [GO:0004674]
d2nv6a__d3tn7b___1			Actinobacteria	Euryarchaeota	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	oxidoreductase activity [GO:0016491]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	oxidoreductase activity [GO:0016491]
d2nvbc2_d1qsgf___1			Firmicutes	Proteobacteria	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]		biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]; membrane [GO:0016020]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]
d2nvbd2_d1btob2__1		Metazoa	Firmicutes	Chordata	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d2nvoa1_d3ppva1__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]		blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	metal ion binding [GO:0046872]; RNA binding [GO:0003723]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d2nvuc1_d5mnje___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2nw2b2_d1a4ja1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2nw3a1_d4a6yl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2nw3b__d4y4kd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2nw6a__d3d2ci___1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d2nwdx1_d1cvka___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2nwdx1_d1lmaa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2nwia1_d2p19a1__1			Euryarchaeota	Actinobacteria		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]						DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2nwic2_d2ahca___1			Euryarchaeota	Proteobacteria		cytosol [GO:0005829]; chorismate lyase activity [GO:0008813]; pyruvate biosynthetic process [GO:0042866]; ubiquinone biosynthetic process [GO:0006744]		pyruvate biosynthetic process [GO:0042866]; ubiquinone biosynthetic process [GO:0006744]		cytosol [GO:0005829]		chorismate lyase activity [GO:0008813]
d2nwid2_d2fa1b2__1			Euryarchaeota	Proteobacteria		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; organic phosphonate transport [GO:0015716]		organic phosphonate transport [GO:0015716]				DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2nwif__d2ahcd___1			Euryarchaeota	Proteobacteria		cytosol [GO:0005829]; chorismate lyase activity [GO:0008813]; pyruvate biosynthetic process [GO:0042866]; ubiquinone biosynthetic process [GO:0006744]		pyruvate biosynthetic process [GO:0042866]; ubiquinone biosynthetic process [GO:0006744]		cytosol [GO:0005829]		chorismate lyase activity [GO:0008813]
d2nwsb__d5tlhd___1		Metazoa	Aquificae	Chordata	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]	I band [GO:0031674]; M band [GO:0031430]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	fructose-bisphosphate aldolase activity [GO:0004332]
d2nx0a__d1yeqa___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2nx1b__d1fwta___1			Aquificae	Aquificae	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]
d2nx1b__d1vpxb1__1			Aquificae	Thermotogae	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d2nx3d__d1wx0j___1			Aquificae	Deinococcus-Thermus	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d2nx3e__d1vr6a2__1			Aquificae	Thermotogae	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]		3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]
d2nx5a2_d3pl6b1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2nx5g__d1i8ml1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2nx5k1_d1ri8a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2nx5q1_d4kv5l1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; antigen binding [GO:0003823]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; aortic valve morphogenesis [GO:0003180]; ATP biosynthetic process [GO:0006754]; BMP signaling pathway [GO:0030509]; cell cycle arrest [GO:0007050]; cell development [GO:0048468]; cell migration [GO:0016477]; cell-cell junction organization [GO:0045216]; cellular response to organic cyclic compound [GO:0071407]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chondrocyte differentiation [GO:0002062]; common-partner SMAD protein phosphorylation [GO:0007182]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; embryonic liver development [GO:1990402]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial to mesenchymal transition [GO:0001837]; evasion or tolerance of host defenses by virus [GO:0019049]; extracellular matrix assembly [GO:0085029]; extrinsic apoptotic signaling pathway [GO:0097191]; heart development [GO:0007507]; heart valve morphogenesis [GO:0003179]; hematopoietic progenitor cell differentiation [GO:0002244]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymph node development [GO:0048535]; macrophage derived foam cell differentiation [GO:0010742]; MAPK cascade [GO:0000165]; membrane protein intracellular domain proteolysis [GO:0031293]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cytolysis [GO:0045918]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of skeletal muscle tissue development [GO:0048642]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; ossification involved in bone remodeling [GO:0043932]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; phosphate-containing compound metabolic process [GO:0006796]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of chemotaxis [GO:0050921]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglia differentiation [GO:0014008]; positive regulation of NAD+ ADP-ribosyltransferase activity [GO:1901666]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular permeability [GO:0043117]; protein export from nucleus [GO:0006611]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor catabolic process [GO:0032801]; regulation of apoptotic process [GO:0042981]; regulation of binding [GO:0051098]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of DNA binding [GO:0051101]; regulation of MAPK cascade [GO:0043408]; regulation of protein import into nucleus [GO:0042306]; regulation of SMAD protein signal transduction [GO:0060390]; regulation of striated muscle tissue development [GO:0016202]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; salivary gland morphogenesis [GO:0007435]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transforming growth factor beta receptor signaling pathway involved in heart development [GO:1905313]; vasculogenesis [GO:0001570]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	aortic valve morphogenesis [GO:0003180]; ATP biosynthetic process [GO:0006754]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell cycle arrest [GO:0007050]; cell development [GO:0048468]; cell migration [GO:0016477]; cellular response to organic cyclic compound [GO:0071407]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chondrocyte differentiation [GO:0002062]; common-partner SMAD protein phosphorylation [GO:0007182]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; embryonic liver development [GO:1990402]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial to mesenchymal transition [GO:0001837]; evasion or tolerance of host defenses by virus [GO:0019049]; extracellular matrix assembly [GO:0085029]; extrinsic apoptotic signaling pathway [GO:0097191]; heart development [GO:0007507]; heart valve morphogenesis [GO:0003179]; hematopoietic progenitor cell differentiation [GO:0002244]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymph node development [GO:0048535]; macrophage derived foam cell differentiation [GO:0010742]; MAPK cascade [GO:0000165]; membrane protein intracellular domain proteolysis [GO:0031293]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytolysis [GO:0045918]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of skeletal muscle tissue development [GO:0048642]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; ossification involved in bone remodeling [GO:0043932]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; phosphate-containing compound metabolic process [GO:0006796]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of chemotaxis [GO:0050921]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglia differentiation [GO:0014008]; positive regulation of NAD+ ADP-ribosyltransferase activity [GO:1901666]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular permeability [GO:0043117]; protein export from nucleus [GO:0006611]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor catabolic process [GO:0032801]; regulation of apoptotic process [GO:0042981]; regulation of binding [GO:0051098]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of DNA binding [GO:0051101]; regulation of MAPK cascade [GO:0043408]; regulation of protein import into nucleus [GO:0042306]; regulation of SMAD protein signal transduction [GO:0060390]; regulation of striated muscle tissue development [GO:0016202]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; salivary gland morphogenesis [GO:0007435]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transforming growth factor beta receptor signaling pathway involved in heart development [GO:1905313]; vasculogenesis [GO:0001570]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]
d2nx5q2_d1i3re2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2nx5r__d2g75c1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2nxbb1_d3p1cb___1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2nxdb__d5p4ia___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2nxga__d1wa3e___1			Aquificae	Thermotogae	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	lyase activity [GO:0016829]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]		cytoplasm [GO:0005737]		3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	lyase activity [GO:0016829]
d2nxhb__d1w3na___1			Aquificae	Crenarchaeota	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]
d2nxhf__d5hwjb___1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	5-dehydro-4-deoxyglucarate dehydratase activity [GO:0047448]; D-glucarate catabolic process [GO:0042838]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	D-glucarate catabolic process [GO:0042838]	cytoplasm [GO:0005737]		3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	5-dehydro-4-deoxyglucarate dehydratase activity [GO:0047448]
d2nxhi__d4rz4c1__1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	fructose metabolic process [GO:0006000]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	fructose 6-phosphate aldolase activity [GO:0097023]
d2nxhl__d4xbsb___1			Aquificae	Firmicutes	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	deoxyribose-phosphate aldolase activity [GO:0004139]
d2nxlb__d4dqeb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2nxma__d5p1ua___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2nxmb__d5ozfa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2nxxc__d5x8xg___1	Metazoa	Metazoa	Arthropoda	Chordata	nucleus [GO:0005634]; ecdysone binding [GO:0035100]; nuclear receptor activity [GO:0004879]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]; ecdysone receptor-mediated signaling pathway [GO:0035076]	histone deacetylase complex [GO:0000118]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; glucocorticoid receptor binding [GO:0035259]; histone deacetylase binding [GO:0042826]; Notch binding [GO:0005112]; nuclear hormone receptor binding [GO:0035257]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]; estrous cycle [GO:0044849]; lactation [GO:0007595]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072365]; regulation of lipid metabolic process [GO:0019216]; response to estradiol [GO:0032355]; response to organonitrogen compound [GO:0010243]	ecdysone receptor-mediated signaling pathway [GO:0035076]	estrous cycle [GO:0044849]; lactation [GO:0007595]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072365]; regulation of lipid metabolic process [GO:0019216]; response to estradiol [GO:0032355]; response to organonitrogen compound [GO:0010243]	nucleus [GO:0005634]	histone deacetylase complex [GO:0000118]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]	ecdysone binding [GO:0035100]; nuclear receptor activity [GO:0004879]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; glucocorticoid receptor binding [GO:0035259]; histone deacetylase binding [GO:0042826]; Notch binding [GO:0005112]; nuclear hormone receptor binding [GO:0035257]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]
d2nxxd__d4apua___1	Metazoa	Metazoa	Arthropoda	Chordata	nucleus [GO:0005634]; ecdysone binding [GO:0035100]; nuclear receptor activity [GO:0004879]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]; ecdysone receptor-mediated signaling pathway [GO:0035076]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; ATPase binding [GO:0051117]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclear receptor activity [GO:0004879]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]; cell-cell signaling [GO:0007267]; epithelial cell maturation [GO:0002070]; lung alveolus development [GO:0048286]; negative regulation of gene expression [GO:0010629]; ovulation from ovarian follicle [GO:0001542]; paracrine signaling [GO:0038001]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; regulation of epithelial cell proliferation [GO:0050678]; signal transduction [GO:0007165]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription initiation from RNA polymerase II promoter [GO:0006367]	ecdysone receptor-mediated signaling pathway [GO:0035076]	cell-cell signaling [GO:0007267]; epithelial cell maturation [GO:0002070]; lung alveolus development [GO:0048286]; negative regulation of gene expression [GO:0010629]; ovulation from ovarian follicle [GO:0001542]; paracrine signaling [GO:0038001]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; regulation of epithelial cell proliferation [GO:0050678]; signal transduction [GO:0007165]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription initiation from RNA polymerase II promoter [GO:0006367]	nucleus [GO:0005634]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]	ecdysone binding [GO:0035100]; nuclear receptor activity [GO:0004879]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]	ATPase binding [GO:0051117]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclear receptor activity [GO:0004879]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]
d2nxyb2_d2cdef2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2nxyc2_d4ynyb2__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d2nxzc1_d4fnlm1__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d2nxzc2_d3cfjl1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ny0b1_d3v0ac___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	extracellular region [GO:0005576]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d2ny0b2_d4hbqa1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; integrin binding involved in cell-matrix adhesion [GO:0098640]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	integrin binding involved in cell-matrix adhesion [GO:0098640]
d2ny0c1_d3eyoa2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ny0c2_d1hhid1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ny0d1_d2ig2h1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ny1c2_d2qr0h1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ny2b1_d5i1il2__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d2ny3b1_d5f7kc1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d2ny4b2_d3bdyl2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ny4c2_d2vc2l1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ny4d1_d5nmla1__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d2ny5c1_d4w4na1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ny5c2_d1mq8a1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]
d2ny5h1_d4p48a1__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d2ny5l1_d3t3mf2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2ny5l2_d1mlba2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ny6b1_d4at6k1__1	Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d2ny6b2_d1ic1b1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]
d2ny6c1_d5x8lb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d2ny6d1_d4irjd2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ny6d1_d5dmjg___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	CD40 receptor complex [GO:0035631]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; varicosity [GO:0043196]; antigen binding [GO:0003823]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]; B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; cellular calcium ion homeostasis [GO:0006874]; cellular response to erythropoietin [GO:0036018]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; inflammatory response [GO:0006954]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein kinase B signaling [GO:0043491]; protein-containing complex assembly [GO:0065003]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; response to cobalamin [GO:0033590]; response to interferon-gamma [GO:0034341]; response to peptide [GO:1901652]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell proliferation [GO:0042100]; CD40 signaling pathway [GO:0023035]; cellular calcium ion homeostasis [GO:0006874]; cellular response to erythropoietin [GO:0036018]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; inflammatory response [GO:0006954]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein-containing complex assembly [GO:0065003]; protein kinase B signaling [GO:0043491]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; response to cobalamin [GO:0033590]; response to interferon-gamma [GO:0034341]; response to peptide [GO:1901652]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	CD40 receptor complex [GO:0035631]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; varicosity [GO:0043196]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase binding [GO:0031625]
d2ny7h2_d1z7zi5__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	structural molecule activity [GO:0005198]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]
d2ny7l2_d1e0ob1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	structural molecule activity [GO:0005198]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2nyba1_d2rcva1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2nybb1_d4f2ni1__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	mitochondrion [GO:0005739]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2nybb2_d1wb8a2__1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2nybc1_d3js4a1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2nybc2_d1xuqa2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	removal of superoxide radicals [GO:0019430]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2nybd2_d2gpca2__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2nytb1_d1mq0a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cytidine to uridine editing [GO:0016554]; DNA demethylation [GO:0080111]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]	cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytidine deaminase activity [GO:0004126]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; cell surface receptor signaling pathway [GO:0007166]; cytidine deamination [GO:0009972]; cytosine metabolic process [GO:0019858]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; neutrophil degranulation [GO:0043312]; protein homotetramerization [GO:0051289]; pyrimidine nucleoside salvage [GO:0043097]; pyrimidine-containing compound salvage [GO:0008655]	cytidine to uridine editing [GO:0016554]; DNA demethylation [GO:0080111]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]	cell surface receptor signaling pathway [GO:0007166]; cytidine deamination [GO:0009972]; cytosine metabolic process [GO:0019858]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; neutrophil degranulation [GO:0043312]; protein homotetramerization [GO:0051289]; pyrimidine-containing compound salvage [GO:0008655]; pyrimidine nucleoside salvage [GO:0043097]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	cytidine deaminase activity [GO:0004126]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	cytidine deaminase activity [GO:0004126]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]
d2nyyc1_d1s7uk___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	negative regulation of neurotransmitter secretion [GO:0046929]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2nyyd2_d2c1ol2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	metal ion binding [GO:0046872]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]		metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d2nz1y__d5corc___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR2 chemokine receptor binding [GO:0031727]; chemokine activity [GO:0008009]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; astrocyte cell migration [GO:0043615]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular homeostasis [GO:0019725]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; helper T cell extravasation [GO:0035684]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of natural killer cell chemotaxis [GO:2000502]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of calcium ion import [GO:0090280]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of T cell activation [GO:0050870]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; viral genome replication [GO:0019079]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium-dependent protein kinase C activity [GO:0004698]; CCR chemokine receptor binding [GO:0048020]; CCR1 chemokine receptor binding [GO:0031726]; CCR5 chemokine receptor binding [GO:0031730]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; phospholipase activator activity [GO:0016004]; protein kinase activity [GO:0004672]; astrocyte cell migration [GO:0043615]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell activation [GO:0001775]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; eosinophil degranulation [GO:0043308]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; granulocyte chemotaxis [GO:0071621]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of bone mineralization [GO:0030502]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast differentiation [GO:0045671]; neutrophil chemotaxis [GO:0030593]; osteoblast differentiation [GO:0001649]; positive regulation of calcium ion import [GO:0090280]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; protein kinase B signaling [GO:0043491]; regulation of behavior [GO:0050795]; regulation of cell shape [GO:0008360]; regulation of sensory perception of pain [GO:0051930]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to cholesterol [GO:0070723]; response to toxic substance [GO:0009636]; signaling [GO:0023052]; T cell chemotaxis [GO:0010818]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; astrocyte cell migration [GO:0043615]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular homeostasis [GO:0019725]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; helper T cell extravasation [GO:0035684]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of natural killer cell chemotaxis [GO:2000502]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of calcium ion import [GO:0090280]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of T cell activation [GO:0050870]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; viral genome replication [GO:0019079]	astrocyte cell migration [GO:0043615]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell activation [GO:0001775]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; eosinophil degranulation [GO:0043308]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; granulocyte chemotaxis [GO:0071621]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of bone mineralization [GO:0030502]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast differentiation [GO:0045671]; neutrophil chemotaxis [GO:0030593]; osteoblast differentiation [GO:0001649]; positive regulation of calcium ion import [GO:0090280]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; protein kinase B signaling [GO:0043491]; regulation of behavior [GO:0050795]; regulation of cell shape [GO:0008360]; regulation of sensory perception of pain [GO:0051930]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to cholesterol [GO:0070723]; response to toxic substance [GO:0009636]; signaling [GO:0023052]; T cell chemotaxis [GO:0010818]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	CCR2 chemokine receptor binding [GO:0031727]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]	calcium-dependent protein kinase C activity [GO:0004698]; CCR1 chemokine receptor binding [GO:0031726]; CCR5 chemokine receptor binding [GO:0031730]; CCR chemokine receptor binding [GO:0048020]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; phospholipase activator activity [GO:0016004]; protein kinase activity [GO:0004672]
d2nz4c__d1nu4b___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]
d2nz5a1_d4g7gb___1			Actinobacteria		heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d2nz5b1_d3czhb1__1		Metazoa	Actinobacteria	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; vitamin D3 25-hydroxylase activity [GO:0030343]; calcitriol biosynthetic process from calciol [GO:0036378]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; response to cesium ion [GO:0010164]; response to ionizing radiation [GO:0010212]; vitamin D metabolic process [GO:0042359]; vitamin metabolic process [GO:0006766]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	calcitriol biosynthetic process from calciol [GO:0036378]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; response to cesium ion [GO:0010164]; response to ionizing radiation [GO:0010212]; vitamin D metabolic process [GO:0042359]; vitamin metabolic process [GO:0006766]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; vitamin D3 25-hydroxylase activity [GO:0030343]
d2nz5b1_d4ejhe___1		Metazoa	Actinobacteria	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d2nz9c2_d3mugg1__1			Firmicutes		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]		metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	
d2nz9d1_d3mffd2__1			Firmicutes		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]		metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	
d2nz9e1_d1u0qb___1			Firmicutes		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]		metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	
d2nz9f2_d1oayj___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	negative regulation of neurotransmitter secretion [GO:0046929]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	
d2nzaa1_d4bf4g___1			Actinobacteria	Actinobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]			heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2nzha__d2qbhl1__1			Firmicutes		cytoplasm [GO:0005737]; tRNA binding [GO:0000049]; protein transport [GO:0015031]		protein transport [GO:0015031]		cytoplasm [GO:0005737]		tRNA binding [GO:0000049]	
d2nzna__d2bqfa___1		Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]		antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2nzob1_d3pgzb1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; tRNA binding [GO:0000049]; protein transport [GO:0015031]	single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]	protein transport [GO:0015031]	DNA replication [GO:0006260]	cytoplasm [GO:0005737]		tRNA binding [GO:0000049]	single-stranded DNA binding [GO:0003697]
d2nzod1_d3nenb1__1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; tRNA binding [GO:0000049]; protein transport [GO:0015031]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	protein transport [GO:0015031]	aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]	tRNA binding [GO:0000049]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d2o06a__d2jg3d1__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; spermidine synthase activity [GO:0004766]; cellular response to leukemia inhibitory factor [GO:1990830]; polyamine biosynthetic process [GO:0006596]; polyamine metabolic process [GO:0006595]; spermidine biosynthetic process [GO:0008295]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	cellular response to leukemia inhibitory factor [GO:1990830]; polyamine biosynthetic process [GO:0006596]; polyamine metabolic process [GO:0006595]; spermidine biosynthetic process [GO:0008295]	DNA restriction-modification system [GO:0009307]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; spermidine synthase activity [GO:0004766]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]
d2o0va__d2ntba___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	pectin catabolic process [GO:0045490]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]
d2o17a__d2vfpa___1			Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	virus tail, fiber [GO:0098024]; endo-1,3-alpha-L-rhamnosidase activity [GO:0052775]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption by virus of host envelope lipopolysaccharide during virus entry [GO:0098995]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]; virion attachment to host cell [GO:0019062]	pectin catabolic process [GO:0045490]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption by virus of host envelope lipopolysaccharide during virus entry [GO:0098995]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	virus tail, fiber [GO:0098024]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	endo-1,3-alpha-L-rhamnosidase activity [GO:0052775]
d2o1da__d1ogmx2__1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; dextranase activity [GO:0033904]; metabolic process [GO:0008152]	pectin catabolic process [GO:0045490]	metabolic process [GO:0008152]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	dextranase activity [GO:0033904]
d2o1oa__d1hm4b___1			Apicomplexa	Actinobacteria	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	metal ion binding [GO:0046872]; pentalenene synthase activity [GO:0050467]; antibiotic biosynthetic process [GO:0017000]	farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	antibiotic biosynthetic process [GO:0017000]			dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]	metal ion binding [GO:0046872]; pentalenene synthase activity [GO:0050467]
d2o1pa1_d2zh1a1__1	Fungi		Ascomycota	Euryarchaeota	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]
d2o20b__d1efaa2__1			Firmicutes	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]
d2o20c__d3ma0b___1			Firmicutes	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]	outer membrane-bounded periplasmic space [GO:0030288]; monosaccharide binding [GO:0048029]; D-xylose metabolic process [GO:0042732]; D-xylose transmembrane transport [GO:0015753]	negative regulation of transcription, DNA-templated [GO:0045892]	D-xylose metabolic process [GO:0042732]; D-xylose transmembrane transport [GO:0015753]	protein-DNA complex [GO:0032993]	outer membrane-bounded periplasmic space [GO:0030288]	DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	monosaccharide binding [GO:0048029]
d2o20c__d5gtaa___1			Firmicutes	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; periplasmic space [GO:0042597]	negative regulation of transcription, DNA-templated [GO:0045892]		protein-DNA complex [GO:0032993]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; periplasmic space [GO:0042597]	DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	
d2o20e__d3ga5a___1			Firmicutes	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]	outer membrane-bounded periplasmic space [GO:0030288]; metal ion binding [GO:0046872]; carbohydrate transport [GO:0008643]; chemotaxis [GO:0006935]	negative regulation of transcription, DNA-templated [GO:0045892]	carbohydrate transport [GO:0008643]; chemotaxis [GO:0006935]	protein-DNA complex [GO:0032993]	outer membrane-bounded periplasmic space [GO:0030288]	DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	metal ion binding [GO:0046872]
d2o25a2_d2gjdc___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]; ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; ATP binding [GO:0005524]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; cell division [GO:0051301]; mitotic spindle elongation [GO:0000022]; protein sumoylation [GO:0016925]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cell division [GO:0051301]; mitotic spindle elongation [GO:0000022]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]	ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]
d2o25a2_d4yc1b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]; ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]; autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]	calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]
d2o25b2_d5ojwb___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]; ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin conjugating enzyme complex [GO:0031371]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; free ubiquitin chain polymerization [GO:0010994]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	free ubiquitin chain polymerization [GO:0010994]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin conjugating enzyme complex [GO:0031371]	ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]
d2o26a1_d3ncca___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; stem cell factor receptor binding [GO:0005173]; cell adhesion [GO:0007155]; ectopic germ cell programmed cell death [GO:0035234]; embryonic hemopoiesis [GO:0035162]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; germ cell development [GO:0007281]; male gonad development [GO:0008584]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mast cell apoptotic process [GO:0033026]; neural crest cell migration [GO:0001755]; ovarian follicle development [GO:0001541]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell proliferation [GO:0070668]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of myeloid leukocyte differentiation [GO:0002763]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of Ras protein signal transduction [GO:0046579]	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	cell adhesion [GO:0007155]; ectopic germ cell programmed cell death [GO:0035234]; embryonic hemopoiesis [GO:0035162]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; germ cell development [GO:0007281]; male gonad development [GO:0008584]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mast cell apoptotic process [GO:0033026]; neural crest cell migration [GO:0001755]; ovarian follicle development [GO:0001541]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell proliferation [GO:0070668]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of myeloid leukocyte differentiation [GO:0002763]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of Ras protein signal transduction [GO:0046579]	cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; stem cell factor receptor binding [GO:0005173]	hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]
d2o2dc__d1kojb___1		Metazoa		Chordata	glycosome [GO:0020015]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	glycosome [GO:0020015]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	glucose-6-phosphate isomerase activity [GO:0004347]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]
d2o2ha__d1mj5a1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; plasma membrane [GO:0005886]; haloalkane dehalogenase activity [GO:0018786]; halogenated hydrocarbon catabolic process [GO:0042206]	periplasmic space [GO:0042597]; haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	halogenated hydrocarbon catabolic process [GO:0042206]	response to toxic substance [GO:0009636]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	haloalkane dehalogenase activity [GO:0018786]	haloalkane dehalogenase activity [GO:0018786]
d2o2ia__d1mx9d___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; plasma membrane [GO:0005886]; haloalkane dehalogenase activity [GO:0018786]; halogenated hydrocarbon catabolic process [GO:0042206]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	halogenated hydrocarbon catabolic process [GO:0042206]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	haloalkane dehalogenase activity [GO:0018786]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d2o2le__d5elcc___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	toxin activity [GO:0090729]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d2o2lf__d2c5cg___1			Proteobacteria		extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]		hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d2o2pb__d5klkc___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2o2qb__d4i3tf___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2o2ra__d1co3a___1	Metazoa		Chordata		cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	
d2o2ra__d3ek1h___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; gamma-aminobutyric acid catabolic process [GO:0009450]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	gamma-aminobutyric acid catabolic process [GO:0009450]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]
d2o2rb__d3fg0a1__1	Metazoa		Chordata		cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	
d2o2rc__d4kwfc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2o39b__d3u6xg2__1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]		
d2o3ca__d1si6x___1	Metazoa	Metazoa	Chordata	Arthropoda	endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; phosphodiesterase I activity [GO:0004528]; RNA binding [GO:0003723]; base-excision repair [GO:0006284]; DNA demethylation [GO:0080111]; heart contraction [GO:0060047]; heart looping [GO:0001947]; negative regulation of apoptotic process [GO:0043066]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]	extracellular space [GO:0005615]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide transport [GO:0030185]; phosphatidylinositol dephosphorylation [GO:0046856]; vasodilation in other organism [GO:0044552]	base-excision repair [GO:0006284]; DNA demethylation [GO:0080111]; heart contraction [GO:0060047]; heart looping [GO:0001947]; negative regulation of apoptotic process [GO:0043066]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]	nitric oxide transport [GO:0030185]; phosphatidylinositol dephosphorylation [GO:0046856]; vasodilation in other organism [GO:0044552]	endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]	extracellular space [GO:0005615]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; phosphodiesterase I activity [GO:0004528]; RNA binding [GO:0003723]	heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2o3cb1_d2o3cc___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; phosphodiesterase I activity [GO:0004528]; RNA binding [GO:0003723]; base-excision repair [GO:0006284]; DNA demethylation [GO:0080111]; heart contraction [GO:0060047]; heart looping [GO:0001947]; negative regulation of apoptotic process [GO:0043066]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]	endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; phosphodiesterase I activity [GO:0004528]; RNA binding [GO:0003723]; base-excision repair [GO:0006284]; DNA demethylation [GO:0080111]; heart contraction [GO:0060047]; heart looping [GO:0001947]; negative regulation of apoptotic process [GO:0043066]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]	base-excision repair [GO:0006284]; DNA demethylation [GO:0080111]; heart contraction [GO:0060047]; heart looping [GO:0001947]; negative regulation of apoptotic process [GO:0043066]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]	base-excision repair [GO:0006284]; DNA demethylation [GO:0080111]; heart contraction [GO:0060047]; heart looping [GO:0001947]; negative regulation of apoptotic process [GO:0043066]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]	endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]	endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; phosphodiesterase I activity [GO:0004528]; RNA binding [GO:0003723]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; phosphodiesterase I activity [GO:0004528]; RNA binding [GO:0003723]
d2o3cb1_d3w2xa___1	Metazoa		Chordata	Euryarchaeota	endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; phosphodiesterase I activity [GO:0004528]; RNA binding [GO:0003723]; base-excision repair [GO:0006284]; DNA demethylation [GO:0080111]; heart contraction [GO:0060047]; heart looping [GO:0001947]; negative regulation of apoptotic process [GO:0043066]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]; DNA demethylation [GO:0080111]; heart contraction [GO:0060047]; heart looping [GO:0001947]; negative regulation of apoptotic process [GO:0043066]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]	DNA repair [GO:0006281]	endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]		class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; phosphodiesterase I activity [GO:0004528]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d2o3cc__d3g1ka___1	Metazoa		Chordata	Euryarchaeota	endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; phosphodiesterase I activity [GO:0004528]; RNA binding [GO:0003723]; base-excision repair [GO:0006284]; DNA demethylation [GO:0080111]; heart contraction [GO:0060047]; heart looping [GO:0001947]; negative regulation of apoptotic process [GO:0043066]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]; DNA demethylation [GO:0080111]; heart contraction [GO:0060047]; heart looping [GO:0001947]; negative regulation of apoptotic process [GO:0043066]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]	DNA repair [GO:0006281]	endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]		class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; phosphodiesterase I activity [GO:0004528]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d2o3da1_d2dgta1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA topoisomerase binding [GO:0044547]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA 3'-end processing [GO:0031124]; mRNA 5'-splice site recognition [GO:0000395]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of gene expression [GO:0010628]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]	alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA 3'-end processing [GO:0031124]; mRNA 5'-splice site recognition [GO:0000395]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]	circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of gene expression [GO:0010628]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA topoisomerase binding [GO:0044547]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2o3ka__d4g3ma1__1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d2o3ka__d5k81c___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; innate immune response [GO:0045087]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	base conversion or substitution editing [GO:0016553]; innate immune response [GO:0045087]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]
d2o3kb__d2d5nc2__1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]; cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	cytidine metabolic process [GO:0046087]; cytosine metabolic process [GO:0019858]; pyrimidine-containing compound salvage [GO:0008655]; UMP salvage [GO:0044206]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; zinc ion binding [GO:0008270]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d2o3qa__d4meja___1	Metazoa		Chordata	Firmicutes	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	transferase activity [GO:0016740]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]		basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]		identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	transferase activity [GO:0016740]
d2o3za2_d2vqfi1__1			Aquificae	Deinococcus-Thermus	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	lipid A biosynthetic process [GO:0009245]	translation [GO:0006412]		ribosome [GO:0005840]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2o3zb1_d1fwlc1__1			Aquificae	Euryarchaeota	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]	lipid A biosynthetic process [GO:0009245]	threonine biosynthetic process [GO:0009088]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]	ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]
d2o3zb2_d2c37r1__1			Aquificae	Crenarchaeota	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	lipid A biosynthetic process [GO:0009245]	rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]	3'-5'-exoribonuclease activity [GO:0000175]
d2o3zb2_d2go4a1__1			Aquificae	Aquificae	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	lipid A biosynthetic process [GO:0009245]	lipid A biosynthetic process [GO:0009245]			metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d2o4ha__d2nyqa___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nucleus [GO:0005634]; aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]		cytosol [GO:0005829]; nucleus [GO:0005634]	extracellular region [GO:0005576]	aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]
d2o4la__d5p83a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2o53a__d4tnub___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	cytosol [GO:0005829]; nucleus [GO:0005634]; aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	cytosol [GO:0005829]; nucleus [GO:0005634]	cytosol [GO:0005829]; nucleus [GO:0005634]	aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2o53b__d2jewa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	proteolysis [GO:0006508]	cytosol [GO:0005829]; nucleus [GO:0005634]	extracellular space [GO:0005615]	aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2o56a2_d1mucb1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; beta-ketoadipate pathway [GO:0042952]; cellular amino acid catabolic process [GO:0009063]		beta-ketoadipate pathway [GO:0042952]; cellular amino acid catabolic process [GO:0009063]			metal ion binding [GO:0046872]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d2o56b2_d4gypa2__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]		D-glucarate catabolic process [GO:0042838]			metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d2o5bx__d3dbje___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2o5ib2_d1twfc2__1		Fungi	Deinococcus-Thermus	Ascomycota	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	transcription, DNA-templated [GO:0006351]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]		cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]
d2o5ox__d3aq7b___1	Metazoa		Chordata	Ciliophora	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2o5qx__d5nb4a___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2o5tx__d2qmbd___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2o5ub__d5byud___1			Proteobacteria	Proteobacteria	acyl-CoA hydrolase activity [GO:0047617]						acyl-CoA hydrolase activity [GO:0047617]	
d2o5uc__d3az9s___1			Proteobacteria	Apicomplexa	acyl-CoA hydrolase activity [GO:0047617]	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]			acyl-CoA hydrolase activity [GO:0047617]	hydro-lyase activity [GO:0016836]
d2o5xl1_d1a1ma1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2o5xl2_d4hv8b1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2o5zl2_d4h0hb1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2o60a__d1avsa___1	Metazoa	Metazoa	Chordata	Chordata	protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin binding [GO:0017022]; protein C-terminus binding [GO:0008022]; calcium-mediated signaling [GO:0019722]	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	calcium-mediated signaling [GO:0019722]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	protein-containing complex [GO:0032991]	troponin complex [GO:0005861]	calcium ion binding [GO:0005509]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin binding [GO:0017022]; protein C-terminus binding [GO:0008022]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]
d2o60a__d5dkra___1	Metazoa	Metazoa	Chordata	Chordata	protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin binding [GO:0017022]; protein C-terminus binding [GO:0008022]; calcium-mediated signaling [GO:0019722]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium-mediated signaling [GO:0019722]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium ion binding [GO:0005509]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin binding [GO:0017022]; protein C-terminus binding [GO:0008022]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d2o61b1_d1ooaa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2o61b2_d1ooaa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2o6ba1_d1pn4a1__1		Fungi	Proteobacteria	Ascomycota	acyl-CoA hydrolase activity [GO:0047617]	peroxisome [GO:0005777]; isomerase activity [GO:0016853]; lyase activity [GO:0016829]; oxidoreductase activity [GO:0016491]; fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation [GO:0006635]		peroxisome [GO:0005777]	acyl-CoA hydrolase activity [GO:0047617]	isomerase activity [GO:0016853]; lyase activity [GO:0016829]; oxidoreductase activity [GO:0016491]
d2o6bb1_d1j1ya___1			Proteobacteria	Deinococcus-Thermus	acyl-CoA hydrolase activity [GO:0047617]	thiolester hydrolase activity [GO:0016790]					acyl-CoA hydrolase activity [GO:0047617]	thiolester hydrolase activity [GO:0016790]
d2o6da__d3lzra___1			Spirochaetes	Proteobacteria	plasma membrane [GO:0005886]	metal ion binding [GO:0046872]			plasma membrane [GO:0005886]			metal ion binding [GO:0046872]
d2o6db__d3lzpb___1			Spirochaetes	Proteobacteria	plasma membrane [GO:0005886]	metal ion binding [GO:0046872]			plasma membrane [GO:0005886]			metal ion binding [GO:0046872]
d2o6eb__d5i0yb1__1			Spirochaetes	Proteobacteria	plasma membrane [GO:0005886]				plasma membrane [GO:0005886]			
d2o6pb2_d3vuad___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; peptidoglycan-based cell wall [GO:0009274]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; heme transport [GO:0015886]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme binding [GO:0020037]	heme transport [GO:0015886]		extracellular region [GO:0005576]; peptidoglycan-based cell wall [GO:0009274]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]	heme binding [GO:0020037]
d2o6ra__d2omya2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]		adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	integral component of membrane [GO:0016021]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]		ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2o6ra__d3e6ja___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d2o6ta2_d5szza___1			Proteobacteria	Proteobacteria	acyl-CoA hydrolase activity [GO:0047617]	thiolester hydrolase activity [GO:0016790]					acyl-CoA hydrolase activity [GO:0047617]	thiolester hydrolase activity [GO:0016790]
d2o6te__d4k4bf___1			Proteobacteria	Proteobacteria	acyl-CoA hydrolase activity [GO:0047617]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]; menaquinone biosynthetic process [GO:0009234]		menaquinone biosynthetic process [GO:0009234]		cytosol [GO:0005829]	acyl-CoA hydrolase activity [GO:0047617]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]
d2o6tg__d3cf8b___1			Proteobacteria	Proteobacteria	acyl-CoA hydrolase activity [GO:0047617]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	acyl-CoA hydrolase activity [GO:0047617]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d2o72a1_d4zt1b1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2o72a2_d3qrba2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d2o7ka__d3zvjr1__1		Metazoa	Firmicutes	Platyhelminthes	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	protein disulfide oxidoreductase activity [GO:0015035]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2o7oa1_d2vpra1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d2o7ub__d1l5ta___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d2o7uc__d1qjma1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	extracellular space [GO:0005615]; specific granule [GO:0042581]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d2o7ud__d4yahx1__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	anchored component of plasma membrane [GO:0046658]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; D-methionine transport [GO:0048473]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	D-methionine transport [GO:0048473]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	anchored component of plasma membrane [GO:0046658]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	
d2o7ue__d2ghaa___1	Metazoa		Chordata	Thermotogae	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	proteasome core complex, alpha-subunit complex [GO:0019773]; carbohydrate transmembrane transporter activity [GO:0015144]; endopeptidase activity [GO:0004175]; ubiquitin-dependent protein catabolic process [GO:0006511]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	ubiquitin-dependent protein catabolic process [GO:0006511]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	proteasome core complex, alpha-subunit complex [GO:0019773]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	carbohydrate transmembrane transporter activity [GO:0015144]; endopeptidase activity [GO:0004175]
d2o7uf__d1n76a2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d2o7ug__d1biya1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	extracellular space [GO:0005615]; specific granule [GO:0042581]; iron ion binding [GO:0005506]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	extracellular space [GO:0005615]; specific granule [GO:0042581]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	iron ion binding [GO:0005506]; serine-type endopeptidase activity [GO:0004252]
d2o7ui__d1dsna___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d2o84x__d1a8fa___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d2o89a__d4xhma___1			Firmicutes	Euryarchaeota	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]	cell [GO:0005623]	protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d2o8aa__d4zvza___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; protein domain specific binding [GO:0019904]; protein phosphatase inhibitor activity [GO:0004864]; glycogen metabolic process [GO:0005977]; negative regulation of protein binding [GO:0032091]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of signal transduction [GO:0009966]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	glycogen metabolic process [GO:0005977]; negative regulation of protein binding [GO:0032091]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of signal transduction [GO:0009966]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; growth cone [GO:0030426]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	protein domain specific binding [GO:0019904]; protein phosphatase inhibitor activity [GO:0004864]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]
d2o8ga__d1su1a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; protein domain specific binding [GO:0019904]; protein phosphatase inhibitor activity [GO:0004864]; glycogen metabolic process [GO:0005977]; negative regulation of protein binding [GO:0032091]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of signal transduction [GO:0009966]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; phosphoric diester hydrolase activity [GO:0008081]; protein homotetramerization [GO:0051289]	glycogen metabolic process [GO:0005977]; negative regulation of protein binding [GO:0032091]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of signal transduction [GO:0009966]	protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; growth cone [GO:0030426]	cytosol [GO:0005829]	protein domain specific binding [GO:0019904]; protein phosphatase inhibitor activity [GO:0004864]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; phosphoric diester hydrolase activity [GO:0008081]
d2o8ha__d4qgeb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; metal ion binding [GO:0046872]
d2o8jb__d4jlga2__1	Metazoa	Metazoa	Chordata	Chordata	nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; C2H2 zinc finger domain binding [GO:0070742]; histone methyltransferase activity (H3-K27 specific) [GO:0046976]; histone methyltransferase activity (H3-K9 specific) [GO:0046974]; histone-lysine N-methyltransferase activity [GO:0018024]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protein-lysine N-methyltransferase activity [GO:0016279]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; DNA methylation [GO:0006306]; histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; regulation of DNA replication [GO:0006275]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; histone-lysine N-methyltransferase activity [GO:0018024]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; heterochromatin organization [GO:0070828]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of histone H3-K9 methylation [GO:0051570]; response to ethanol [GO:0045471]	cellular response to starvation [GO:0009267]; DNA methylation [GO:0006306]; histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; regulation of DNA replication [GO:0006275]; regulation of signal transduction by p53 class mediator [GO:1901796]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; heterochromatin organization [GO:0070828]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of histone H3-K9 methylation [GO:0051570]; response to ethanol [GO:0045471]	nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	C2H2 zinc finger domain binding [GO:0070742]; histone-lysine N-methyltransferase activity [GO:0018024]; histone methyltransferase activity (H3-K27 specific) [GO:0046976]; histone methyltransferase activity (H3-K9 specific) [GO:0046974]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protein-lysine N-methyltransferase activity [GO:0016279]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; histone-lysine N-methyltransferase activity [GO:0018024]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]
d2o8vb__d1m7ta1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d2o93l2_d1bvoa___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d2o93m2_d1le9a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2o9ca1_d3vv4b1__1			Deinococcus-Thermus	Cyanobacteria	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	integral component of membrane [GO:0016021]; protein-chromophore linkage [GO:0018298]; signal transduction [GO:0007165]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	protein-chromophore linkage [GO:0018298]; signal transduction [GO:0007165]		integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	
d2o9ca2_d3nhqh1__1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d2o9ka__d1gg2b___1	Metazoa	Metazoa	Chordata	Chordata	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]	G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]
d2o9ma__d3qn9b___1				Proteobacteria		6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]		queuosine biosynthetic process [GO:0008616]				6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d2o9mg__d2yzbd1__1				Actinobacteria		urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]				urate oxidase activity [GO:0004846]
d2o9mg__d5m98h2__1		Metazoa		Chordata		peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]
d2o9qa__d5gj4h___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2o9ta__d1ciua4__1			Firmicutes	Firmicutes	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2oa7a2_d3p90a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]
d2oa7b2_d2gsqa2__1	Metazoa	Metazoa	Chordata	Mollusca	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	cytoplasm [GO:0005737]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d2oaca2_d4ofnb1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	transferase activity [GO:0016740]
d2oacb2_d2okab___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	
d2oada1_d2c3qb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]
d2oada2_d22gsa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2oada2_d4yh2d1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	cytoplasm [GO:0005737]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d2oaea1_d2g5ta1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2oaga2_d3gzje___1	Metazoa	Viridiplantae	Chordata	Streptophyta	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	polyneuridine-aldehyde esterase activity [GO:0050529]; alkaloid metabolic process [GO:0009820]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	alkaloid metabolic process [GO:0009820]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	polyneuridine-aldehyde esterase activity [GO:0050529]
d2oagd2_d2baga___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	acetylcholinesterase activity [GO:0003990]
d2oatc__d7aatb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]	kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]
d2obaa1_d1fbxd___1			Proteobacteria	Proteobacteria	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]; queuosine biosynthetic process [GO:0008616]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	queuosine biosynthetic process [GO:0008616]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d2obad1_d3qn0d___1			Proteobacteria	Proteobacteria	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]; queuosine biosynthetic process [GO:0008616]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	queuosine biosynthetic process [GO:0008616]	queuosine biosynthetic process [GO:0008616]			6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d2obaf1_d5ll1a1__1		Metazoa	Proteobacteria	Chordata	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]; queuosine biosynthetic process [GO:0008616]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	queuosine biosynthetic process [GO:0008616]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]	urate oxidase activity [GO:0004846]
d2obeb1_d2bvin2__1					host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]; structural molecule activity [GO:0005198]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]		microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]		host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]		structural molecule activity [GO:0005198]	
d2obeb1_d5tiqb2__1					host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]; structural molecule activity [GO:0005198]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]		host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]	viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d2obha__d2khna1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 2 complex [GO:0000111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of DNA damage [GO:0090734]; XPC complex [GO:0071942]; bubble DNA binding [GO:0000405]; damaged DNA binding [GO:0003684]; heteroduplex DNA loop binding [GO:0000404]; protein-containing complex binding [GO:0044877]; single-stranded DNA binding [GO:0003697]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; intra-S DNA damage checkpoint [GO:0031573]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to UV-B [GO:0010224]; UV-damage excision repair [GO:0070914]; UV-damage excision repair, DNA incision [GO:1990731]	apical dendrite [GO:0097440]; calyx of Held [GO:0044305]; cell junction [GO:0030054]; clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endocytic vesicle [GO:0030139]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; postsynaptic actin cytoskeleton [GO:0098871]; presynaptic endocytic zone [GO:0098833]; recycling endosome [GO:0055037]; calcium ion binding [GO:0005509]; guanyl-nucleotide exchange factor activity [GO:0005085]; kinase activator activity [GO:0019209]; molecular adaptor activity [GO:0060090]; proline-rich region binding [GO:0070064]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; brain development [GO:0007420]; cellular protein localization [GO:0034613]; ephrin receptor signaling pathway [GO:0048013]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; membrane organization [GO:0061024]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of apoptotic process [GO:0043065]; positive regulation of caveolin-mediated endocytosis [GO:2001288]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of protein kinase B signaling [GO:0051897]; protein transport [GO:0015031]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle endocytosis [GO:0048488]; viral process [GO:0016032]	DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; intra-S DNA damage checkpoint [GO:0031573]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to UV-B [GO:0010224]; UV-damage excision repair [GO:0070914]; UV-damage excision repair, DNA incision [GO:1990731]	brain development [GO:0007420]; cellular protein localization [GO:0034613]; ephrin receptor signaling pathway [GO:0048013]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; membrane organization [GO:0061024]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of apoptotic process [GO:0043065]; positive regulation of caveolin-mediated endocytosis [GO:2001288]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of protein kinase B signaling [GO:0051897]; protein transport [GO:0015031]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle endocytosis [GO:0048488]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 2 complex [GO:0000111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of DNA damage [GO:0090734]; XPC complex [GO:0071942]	apical dendrite [GO:0097440]; calyx of Held [GO:0044305]; cell junction [GO:0030054]; clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endocytic vesicle [GO:0030139]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; postsynaptic actin cytoskeleton [GO:0098871]; presynaptic endocytic zone [GO:0098833]; recycling endosome [GO:0055037]	bubble DNA binding [GO:0000405]; damaged DNA binding [GO:0003684]; heteroduplex DNA loop binding [GO:0000404]; protein-containing complex binding [GO:0044877]; single-stranded DNA binding [GO:0003697]	calcium ion binding [GO:0005509]; guanyl-nucleotide exchange factor activity [GO:0005085]; kinase activator activity [GO:0019209]; molecular adaptor activity [GO:0060090]; proline-rich region binding [GO:0070064]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]
d2obhb__d4ggfs___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 2 complex [GO:0000111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of DNA damage [GO:0090734]; XPC complex [GO:0071942]; bubble DNA binding [GO:0000405]; damaged DNA binding [GO:0003684]; heteroduplex DNA loop binding [GO:0000404]; protein-containing complex binding [GO:0044877]; single-stranded DNA binding [GO:0003697]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; intra-S DNA damage checkpoint [GO:0031573]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to UV-B [GO:0010224]; UV-damage excision repair [GO:0070914]; UV-damage excision repair, DNA incision [GO:1990731]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; intra-S DNA damage checkpoint [GO:0031573]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to UV-B [GO:0010224]; UV-damage excision repair [GO:0070914]; UV-damage excision repair, DNA incision [GO:1990731]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 2 complex [GO:0000111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of DNA damage [GO:0090734]; XPC complex [GO:0071942]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	bubble DNA binding [GO:0000405]; damaged DNA binding [GO:0003684]; heteroduplex DNA loop binding [GO:0000404]; protein-containing complex binding [GO:0044877]; single-stranded DNA binding [GO:0003697]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d2obkc__d1zofb___1			Proteobacteria	Proteobacteria		cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]; cytoplasm [GO:0005737]		peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2obke__d1ykaa___1			Proteobacteria	Proteobacteria		cell [GO:0005623]; cytosol [GO:0005829]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]; cytosol [GO:0005829]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]
d2obkh__d2okaa___1			Proteobacteria	Proteobacteria								
d2obkh__d4rqra1__1		Metazoa	Proteobacteria	Chordata		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; glutathione oxidoreductase activity [GO:0097573]; protein N-terminus binding [GO:0047485]; cell redox homeostasis [GO:0045454]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of membrane potential [GO:0045838]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein deglutathionylation [GO:0080058]		cell redox homeostasis [GO:0045454]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of membrane potential [GO:0045838]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein deglutathionylation [GO:0080058]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]		electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; glutathione oxidoreductase activity [GO:0097573]; protein N-terminus binding [GO:0047485]
d2obva1_d1rg9a2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; methionine catabolic process [GO:0009087]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; S-adenosylmethionine biosynthetic process [GO:0006556]; selenium compound metabolic process [GO:0001887]; sulfur amino acid metabolic process [GO:0000096]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	methionine catabolic process [GO:0009087]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; S-adenosylmethionine biosynthetic process [GO:0006556]; selenium compound metabolic process [GO:0001887]; sulfur amino acid metabolic process [GO:0000096]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d2obva3_d5a1ia3__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; methionine catabolic process [GO:0009087]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; S-adenosylmethionine biosynthetic process [GO:0006556]; selenium compound metabolic process [GO:0001887]; sulfur amino acid metabolic process [GO:0000096]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; S-adenosylmethionine biosynthetic process [GO:0006556]; selenium compound metabolic process [GO:0001887]; sulfur amino acid metabolic process [GO:0000096]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d2obxe__d1rvvf___1			Proteobacteria	Firmicutes	riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin synthase complex [GO:0009349]	cytosol [GO:0005829]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d2obxh__d1ejba___1		Fungi	Proteobacteria	Ascomycota	riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]; 6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin synthase complex [GO:0009349]	cytoplasm [GO:0005737]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; riboflavin synthase complex [GO:0009349]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]	6,7-dimethyl-8-ribityllumazine synthase activity [GO:0000906]
d2ocga__d4wy5b___1	Metazoa	Fungi	Chordata	Mucoromycota	mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; alpha-amino-acid esterase activity [GO:0047658]; cellular amino acid metabolic process [GO:0006520]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	methyl indole-3-acetate esterase activity [GO:0080030]	cellular amino acid metabolic process [GO:0006520]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		alpha-amino-acid esterase activity [GO:0047658]	methyl indole-3-acetate esterase activity [GO:0080030]
d2ocjb__d2j1wb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d2ocjc__d3wtsa1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]
d2od8a1_d3fdsd2__1	Fungi		Ascomycota	Crenarchaeota	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	PCNA complex [GO:0043626]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d2odeb__d1fqkd___1	Metazoa	Metazoa	Chordata	Chordata	dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; neuronal cell body membrane [GO:0032809]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; synapse [GO:0045202]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of dopamine receptor signaling pathway [GO:0060159]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of dopamine receptor signaling pathway [GO:0060159]	adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; neuronal cell body membrane [GO:0032809]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; synapse [GO:0045202]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d2odeb__d2i59a1__1	Metazoa	Metazoa	Chordata	Chordata	dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; neuronal cell body membrane [GO:0032809]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; synapse [GO:0045202]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of dopamine receptor signaling pathway [GO:0060159]	axon terminus [GO:0043679]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to amphetamine [GO:0001975]	G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of dopamine receptor signaling pathway [GO:0060159]	G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to amphetamine [GO:0001975]	dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; neuronal cell body membrane [GO:0032809]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; synapse [GO:0045202]	axon terminus [GO:0043679]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]
d2odfa1_d2v77b___1		Metazoa	Proteobacteria	Chordata		extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]		extracellular space [GO:0005615]		metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2odfc__d2pj1b___1		Metazoa	Proteobacteria	Chordata		extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]		extracellular space [GO:0005615]		metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2odfe__d1q7l.1__1		Metazoa	Proteobacteria	Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; aminoacylase activity [GO:0004046]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; cellular amino acid metabolic process [GO:0006520]; xenobiotic metabolic process [GO:0006805]		cellular amino acid metabolic process [GO:0006520]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		aminoacylase activity [GO:0004046]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]
d2odfh__d2pjaa___1		Metazoa	Proteobacteria	Chordata		extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]		extracellular space [GO:0005615]		metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2odpa1_d1zopa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; positive regulation of apoptotic cell clearance [GO:2000427]; regulation of complement activation [GO:0030449]; response to nutrient [GO:0007584]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; positive regulation of apoptotic cell clearance [GO:2000427]; regulation of complement activation [GO:0030449]; response to nutrient [GO:0007584]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]
d2odqa1_d3q3gi___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; complement activation, classical pathway [GO:0006958]; response to nutrient [GO:0007584]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	complement activation, classical pathway [GO:0006958]; response to nutrient [GO:0007584]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	extracellular region [GO:0005576]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	serine-type endopeptidase activity [GO:0004252]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]
d2oe1a__d4pgtb2__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; mitochondrion [GO:0005739]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2oela1_d1rcov2__1		Viridiplantae	Firmicutes	Streptophyta	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity [GO:0043715]; magnesium ion binding [GO:0000287]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity [GO:0043715]; magnesium ion binding [GO:0000287]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2oema1_d1gehd2__1			Firmicutes	Euryarchaeota	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity [GO:0043715]; magnesium ion binding [GO:0000287]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	carbon fixation [GO:0015977]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]			2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity [GO:0043715]; magnesium ion binding [GO:0000287]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2oemb1_d1upme1__1		Viridiplantae	Firmicutes	Streptophyta	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity [GO:0043715]; magnesium ion binding [GO:0000287]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	carbon fixation [GO:0015977]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		chloroplast [GO:0009507]	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity [GO:0043715]; magnesium ion binding [GO:0000287]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2of8b1_d1hqqb___1	Metazoa		Chordata	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2ofcb__d1o72b___1		Metazoa		Cnidaria		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]		channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]
d2ofdb__d1gwyb___1		Metazoa		Cnidaria		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]		channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]
d2ofea__d1iazb___1		Metazoa		Cnidaria		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]		channel activity [GO:0015267]; toxin activity [GO:0090729]
d2ofea__d3qdta___1		Fungi		Basidiomycota		carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]
d2ofmx__d2ju8a___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; lysophospholipid:sodium symporter activity [GO:0051978]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]	vasodilation [GO:0042311]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]	extracellular region [GO:0005576]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; lysophospholipid:sodium symporter activity [GO:0051978]; phospholipid binding [GO:0005543]
d2ofna1_d4laxa2__1		Metazoa	Apicomplexa	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein dimerization activity [GO:0046983]; chaperone-mediated protein folding [GO:0061077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein-containing complex localization [GO:0031503]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	chaperone-mediated protein folding [GO:0061077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein-containing complex localization [GO:0031503]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein dimerization activity [GO:0046983]	ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]
d2ofrx__d2np1a___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	vasodilation [GO:0042311]	vasodilation [GO:0042311]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]
d2ofwd__d4ymvj___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; nitrogen compound transport [GO:0071705]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	nitrogen compound transport [GO:0071705]	cytosol [GO:0005829]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	transmembrane transporter activity [GO:0022857]
d2ofxa1_d1dg1g3__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytosol [GO:0005829]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2og1a__d3v1kb___1			Proteobacteria	Proteobacteria	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; aromatic compound catabolic process [GO:0019439]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]
d2og1b__d4wy8d1__1		Fungi	Proteobacteria	Mucoromycota	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; aromatic compound catabolic process [GO:0019439]	methyl indole-3-acetate esterase activity [GO:0080030]	aromatic compound catabolic process [GO:0019439]				2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]	methyl indole-3-acetate esterase activity [GO:0080030]
d2ogpa__d3stjg2__1	Metazoa		Chordata	Proteobacteria	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; axonal growth cone [GO:0044295]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell cortex [GO:0005938]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; endomembrane system [GO:0012505]; internode region of axon [GO:0033269]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein phosphatase binding [GO:0019903]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; protein localization [GO:0008104]; protein targeting to membrane [GO:0006612]; regulation of cellular localization [GO:0060341]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; protein localization [GO:0008104]; protein targeting to membrane [GO:0006612]; regulation of cellular localization [GO:0060341]	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; axonal growth cone [GO:0044295]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; endomembrane system [GO:0012505]; internode region of axon [GO:0033269]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]	identical protein binding [GO:0042802]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol binding [GO:0035091]; protein phosphatase binding [GO:0019903]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]
d2ogza2_d3i2fa1__1	Metazoa		Chordata	Actinobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cocaine catabolic process [GO:0050784]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]
d2oh9a__d1cohc___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2ohaa__d3kmfc___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2ohba__d4hrrf___1	Metazoa	Metazoa	Chordata	Mollusca	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2ohdf__d3jqmc___1			Crenarchaeota	Deinococcus-Thermus	cyclic pyranopterin monophosphate synthase activity [GO:0061799]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cyclic pyranopterin monophosphate synthase activity [GO:0061799]; GTP binding [GO:0005525]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]			cyclic pyranopterin monophosphate synthase activity [GO:0061799]	cyclic pyranopterin monophosphate synthase activity [GO:0061799]; GTP binding [GO:0005525]
d2ohha2_d4cf6a___1		Metazoa	Euryarchaeota	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d2ohhb1_d1x8ia___1			Euryarchaeota	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2ohhb2_d4yaua1__1		Metazoa	Euryarchaeota	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]		carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d2ohhe2_d3f6sd___1			Euryarchaeota	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2ohia2_d4zvmb___1		Metazoa	Euryarchaeota	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d2ohib1_d2zdwa___1			Euryarchaeota		electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]						electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	
d2ohib1_d5a5zc1__1			Euryarchaeota	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2ohib2_d1ycfc1__1			Euryarchaeota	Firmicutes	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d2ohie1_d2fk6a1__1			Euryarchaeota	Firmicutes	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	3'-tRNA processing endoribonuclease activity [GO:0042781]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	3'-tRNA processing endoribonuclease activity [GO:0042781]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d2ohih1_d3idza___1			Euryarchaeota	Deinococcus-Thermus	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]		rRNA processing [GO:0006364]		cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2ohii1_d2yhee1__1			Euryarchaeota	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]
d2ohii2_d1ftga___1			Euryarchaeota	Cyanobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]		cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]		cell [GO:0005623]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2ohii2_d3fjoa1__1		Metazoa	Euryarchaeota	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d2ohja2_d1x77b___1			Euryarchaeota	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; protein homodimerization activity [GO:0042803]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cytosol [GO:0005829]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; protein homodimerization activity [GO:0042803]
d2ohjb1_d2bmia___1			Euryarchaeota	Bacteroidetes	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2ohjb1_d4exsa1__1			Euryarchaeota	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2ohje2_d1ycgc1__1			Euryarchaeota	Firmicutes	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d2oi4x__d5deya___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; manganese ion binding [GO:0030145]; protein serine/threonine kinase activity [GO:0004674]; ribosomal small subunit binding [GO:0043024]; transcription factor binding [GO:0008134]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular detoxification [GO:1990748]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan metabolic process [GO:0030212]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561]	actin filament [GO:0005884]; axon [GO:0030424]; cell-cell junction [GO:0005911]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; focal adhesion [GO:0005925]; intercalated disc [GO:0014704]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Z disc [GO:0030018]; ATP binding [GO:0005524]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; actin cytoskeleton reorganization [GO:0031532]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; branching morphogenesis of an epithelial tube [GO:0048754]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cerebellum development [GO:0021549]; chromatin remodeling [GO:0006338]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; exocytosis [GO:0006887]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; neuron projection morphogenesis [GO:0048812]; positive regulation of axon extension [GO:0045773]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; response to hypoxia [GO:0001666]; signal transduction by protein phosphorylation [GO:0023014]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; wound healing [GO:0042060]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular detoxification [GO:1990748]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan metabolic process [GO:0030212]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561]	actin cytoskeleton reorganization [GO:0031532]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; branching morphogenesis of an epithelial tube [GO:0048754]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cerebellum development [GO:0021549]; chromatin remodeling [GO:0006338]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; exocytosis [GO:0006887]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; neuron projection morphogenesis [GO:0048812]; positive regulation of axon extension [GO:0045773]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; response to hypoxia [GO:0001666]; signal transduction by protein phosphorylation [GO:0023014]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	actin filament [GO:0005884]; axon [GO:0030424]; cell-cell junction [GO:0005911]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; focal adhesion [GO:0005925]; intercalated disc [GO:0014704]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Z disc [GO:0030018]	ATP binding [GO:0005524]; manganese ion binding [GO:0030145]; protein serine/threonine kinase activity [GO:0004674]; ribosomal small subunit binding [GO:0043024]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]
d2oi5b1_d1kk6a___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	response to antibiotic [GO:0046677]	cytosol [GO:0005829]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	transferase activity, transferring acyl groups [GO:0016746]
d2oi6b1_d4mfgd1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	metal ion binding [GO:0046872]; transferase activity, transferring acyl groups [GO:0016746]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytosol [GO:0005829]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	metal ion binding [GO:0046872]; transferase activity, transferring acyl groups [GO:0016746]
d2oi7b1_d1yp3b1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	amyloplast [GO:0009501]; chloroplast [GO:0009507]; ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]; glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cytosol [GO:0005829]	amyloplast [GO:0009501]; chloroplast [GO:0009507]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]
d2oi7b1_d5depb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]
d2oi7b2_d1gx0a___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	cytosol [GO:0005829]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d2oi9c__d3hfmh1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	T cell receptor complex [GO:0042101]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2oifd__d1eyxk___1	Viridiplantae		Streptophyta	Rhodophyta	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	
d2oife__d2hbsb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2oifg__d3wcvc___1	Viridiplantae	Metazoa	Streptophyta	Annelida	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2oiha__d1nrca___1	Metazoa		Chordata		nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]		mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]		nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]		identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	
d2oila__d1vytb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic vesicle [GO:0031410]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; pseudopodium [GO:0031143]; pseudopodium membrane [GO:0031260]; recycling endosome [GO:0055037]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin V binding [GO:0031489]; epithelial cell morphogenesis [GO:0003382]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; pseudopodium organization [GO:0031268]; Rab protein signal transduction [GO:0032482]; regulation of vesicle-mediated transport [GO:0060627]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cytoplasm [GO:0005737]; L-type voltage-gated calcium channel complex [GO:1990454]; synapse [GO:0045202]; voltage-gated calcium channel complex [GO:0005891]; calcium channel regulator activity [GO:0005246]; high voltage-gated calcium channel activity [GO:0008331]; protein kinase binding [GO:0019901]; voltage-gated calcium channel activity [GO:0005245]; calcium ion transmembrane transport [GO:0070588]; calcium ion transmembrane transport via high voltage-gated calcium channel [GO:0061577]; calcium ion transport [GO:0006816]; calcium ion transport into cytosol [GO:0060402]; cellular response to oxygen-glucose deprivation [GO:0090650]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; negative regulation of detection of mechanical stimulus involved in sensory perception of touch [GO:1905788]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; neuromuscular junction development [GO:0007528]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of high voltage-gated calcium channel activity [GO:1901843]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; protein localization to plasma membrane [GO:0072659]; regulation of membrane hyperpolarization [GO:1902630]; regulation of membrane repolarization during action potential [GO:0098903]; regulation of voltage-gated calcium channel activity [GO:1901385]; T cell receptor signaling pathway [GO:0050852]	epithelial cell morphogenesis [GO:0003382]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell migration [GO:0010634]; pseudopodium organization [GO:0031268]; Rab protein signal transduction [GO:0032482]; regulation of vesicle-mediated transport [GO:0060627]	calcium ion transmembrane transport [GO:0070588]; calcium ion transmembrane transport via high voltage-gated calcium channel [GO:0061577]; calcium ion transport [GO:0006816]; calcium ion transport into cytosol [GO:0060402]; cellular response to oxygen-glucose deprivation [GO:0090650]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; negative regulation of detection of mechanical stimulus involved in sensory perception of touch [GO:1905788]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; neuromuscular junction development [GO:0007528]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of high voltage-gated calcium channel activity [GO:1901843]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; protein localization to plasma membrane [GO:0072659]; regulation of membrane hyperpolarization [GO:1902630]; regulation of membrane repolarization during action potential [GO:0098903]; regulation of voltage-gated calcium channel activity [GO:1901385]; T cell receptor signaling pathway [GO:0050852]	cytoplasmic vesicle [GO:0031410]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; pseudopodium [GO:0031143]; pseudopodium membrane [GO:0031260]; recycling endosome [GO:0055037]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cytoplasm [GO:0005737]; L-type voltage-gated calcium channel complex [GO:1990454]; synapse [GO:0045202]; voltage-gated calcium channel complex [GO:0005891]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin V binding [GO:0031489]	calcium channel regulator activity [GO:0005246]; high voltage-gated calcium channel activity [GO:0008331]; protein kinase binding [GO:0019901]; voltage-gated calcium channel activity [GO:0005245]
d2oipa1_d4qlgb___1												
d2oipe1_d3nrra1__1				Apicomplexa		dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]
d2oj1a__d4n2da1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; chromatin-mediated maintenance of transcription [GO:0048096]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]	oxidation-reduction process [GO:0055114]	cellular response to leukemia inhibitory factor [GO:1990830]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin organization [GO:0006325]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]
d2oj1b__d3omib2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2oj6c2_d1uxac___1					viral outer capsid [GO:0039624]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral outer capsid [GO:0039624]	viral capsid [GO:0019028]		metal ion binding [GO:0046872]
d2oj6d1_d3f0yg___1					viral outer capsid [GO:0039624]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral outer capsid [GO:0039624]	viral capsid [GO:0019028]		
d2oj6e1_d4k6te___1					viral outer capsid [GO:0039624]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral outer capsid [GO:0039624]	viral capsid [GO:0019028]		metal ion binding [GO:0046872]
d2ojda1_d3vooa___1				Proteobacteria		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]						heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2ojeb1_d3kdma1__1			Tenericutes									
d2ojeb2_d1xh3a2__1		Metazoa	Tenericutes	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ojef1_d1f2xl___1			Tenericutes									
d2ojef2_d4f7ea1__1		Metazoa	Tenericutes	Chordata		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]		
d2ojta__d2n44a___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d2ojta__d4ykpa___1	Metazoa	Metazoa	Chordata	Ctenophora (ctenophores)	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ionotropic glutamate receptor activity [GO:0004970]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]		cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	ionotropic glutamate receptor activity [GO:0004970]
d2ojua2_d4s1jb___1	Metazoa		Chordata		catalytic step 2 spliceosome [GO:0071013]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	protein folding [GO:0006457]	catalytic step 2 spliceosome [GO:0071013]		peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2ojzh1_d5dxwa___1	Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d2ojzl1_d1kn4l1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ojzl1_d4k3em2__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d2ojzm1_d1yehl1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ojzm2_d3zhdb1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ok0h1_d3qh3d2__1	Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d2okaa__d2pn8h1__1		Metazoa	Proteobacteria	Chordata		cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]		4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]		cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]		protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d2okac__d2c0gb2__1		Metazoa	Proteobacteria	Arthropoda		endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; protein homodimerization activity [GO:0042803]; dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]		dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]		endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]		protein homodimerization activity [GO:0042803]
d2okad__d2a4ha1__1		Metazoa	Proteobacteria	Arthropoda		cell [GO:0005623]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]		disulfide oxidoreductase activity [GO:0015036]
d2okba__d4apzh___1				Firmicutes	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2okbb__d2xcda___1				Firmicutes	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2okbc__d2xy3c___1				Firmicutes	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2okdc__d3ehwx___1		Metazoa		Chordata	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]		extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d2okea__d1mq7a___1				Actinobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2okeb__d4apz6___1				Firmicutes	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2ol0b__d4apzj___1				Firmicutes	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2ol1a__d5vjyd1__1				Heterolobosea	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2ol3a1_d2wzpd1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	virus tail, baseplate [GO:0098025]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2ol3b__d4q97b1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2ol3h1_d3r4dc2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary membrane [GO:0060170]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lateral plasma membrane [GO:0016328]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; actin binding [GO:0003779]; bile acid transmembrane transporter activity [GO:0015125]; calmodulin binding [GO:0005516]; filamin binding [GO:0031005]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; Toll-like receptor binding [GO:0035325]; virus receptor activity [GO:0001618]; bile acid and bile salt transport [GO:0015721]; blood vessel development [GO:0001568]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; common myeloid progenitor cell proliferation [GO:0035726]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; insulin catabolic process [GO:1901143]; insulin receptor internalization [GO:0038016]; negative regulation of bone resorption [GO:0045779]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of vascular permeability [GO:0043116]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of vasculogenesis [GO:2001214]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell growth [GO:0001558]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell migration [GO:0010594]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of homophilic cell adhesion [GO:1903385]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of sprouting angiogenesis [GO:1903670]; wound healing, spreading of cells [GO:0044319]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	bile acid and bile salt transport [GO:0015721]; blood vessel development [GO:0001568]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; common myeloid progenitor cell proliferation [GO:0035726]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; insulin catabolic process [GO:1901143]; insulin receptor internalization [GO:0038016]; negative regulation of bone resorption [GO:0045779]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of vascular permeability [GO:0043116]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of vasculogenesis [GO:2001214]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell growth [GO:0001558]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell migration [GO:0010594]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of homophilic cell adhesion [GO:1903385]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of sprouting angiogenesis [GO:1903670]; wound healing, spreading of cells [GO:0044319]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell surface [GO:0009986]; ciliary membrane [GO:0060170]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lateral plasma membrane [GO:0016328]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	actin binding [GO:0003779]; bile acid transmembrane transporter activity [GO:0015125]; calmodulin binding [GO:0005516]; filamin binding [GO:0031005]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; Toll-like receptor binding [GO:0035325]; virus receptor activity [GO:0001618]
d2ol3h2_d1n5aa2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2olda1_d2vh5l___1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]		GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d2olda1_d3u30b1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]		protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2olda2_d1h3ub2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2olda2_d3qh3a1__1												
d2olea2_d1dqzb___1	Metazoa		Chordata	Actinobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell wall [GO:0005618]; extracellular region [GO:0005576]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; extracellular region [GO:0005576]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]
d2oleb2_d2ajdd2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d2olkb1_d3b5yc1__1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]				integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATP binding [GO:0005524]	ATPase activity [GO:0016887]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]
d2olqa2_d4r43a1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cell [GO:0005623]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; cellular response to glucose stimulus [GO:0071333]; cellular response to iron ion starvation [GO:0010106]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to host immune response [GO:0052572]; response to lipid [GO:0033993]; response to starvation [GO:0042594]	gluconeogenesis [GO:0006094]	cellular response to glucose stimulus [GO:0071333]; cellular response to iron ion starvation [GO:0010106]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to host immune response [GO:0052572]; response to lipid [GO:0033993]; response to starvation [GO:0042594]	cytosol [GO:0005829]	cell [GO:0005623]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]	GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]
d2om5a2_d3upcj___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of postsynaptic membrane [GO:0099025]; axon [GO:0030424]; cell surface [GO:0009986]; juxtaparanode region of axon [GO:0044224]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; node of Ranvier [GO:0033268]; plasma membrane [GO:0005886]; synapse [GO:0045202]; carbohydrate binding [GO:0030246]; cell-cell adhesion mediator activity [GO:0098632]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]; adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cerebral cortex GABAergic interneuron migration [GO:0021853]; clustering of voltage-gated potassium channels [GO:0045163]; dendrite self-avoidance [GO:0070593]; establishment of protein localization to juxtaparanode region of axon [GO:0071206]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; learning [GO:0007612]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; positive regulation of protein processing [GO:0010954]; presynaptic membrane organization [GO:0097090]; protein localization to juxtaparanode region of axon [GO:0071205]; receptor internalization [GO:0031623]; regulation of astrocyte differentiation [GO:0048710]; regulation of axon diameter [GO:0031133]; regulation of neuronal synaptic plasticity [GO:0048168]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adult walking behavior [GO:0007628]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cerebral cortex GABAergic interneuron migration [GO:0021853]; clustering of voltage-gated potassium channels [GO:0045163]; dendrite self-avoidance [GO:0070593]; establishment of protein localization to juxtaparanode region of axon [GO:0071206]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; learning [GO:0007612]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; positive regulation of protein processing [GO:0010954]; presynaptic membrane organization [GO:0097090]; protein localization to juxtaparanode region of axon [GO:0071205]; receptor internalization [GO:0031623]; regulation of astrocyte differentiation [GO:0048710]; regulation of axon diameter [GO:0031133]; regulation of neuronal synaptic plasticity [GO:0048168]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	anchored component of postsynaptic membrane [GO:0099025]; axon [GO:0030424]; cell surface [GO:0009986]; juxtaparanode region of axon [GO:0044224]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; node of Ranvier [GO:0033268]; plasma membrane [GO:0005886]; synapse [GO:0045202]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; cell-cell adhesion mediator activity [GO:0098632]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2om5a4_d4qhua1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of postsynaptic membrane [GO:0099025]; axon [GO:0030424]; cell surface [GO:0009986]; juxtaparanode region of axon [GO:0044224]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; node of Ranvier [GO:0033268]; plasma membrane [GO:0005886]; synapse [GO:0045202]; carbohydrate binding [GO:0030246]; cell-cell adhesion mediator activity [GO:0098632]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]; adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cerebral cortex GABAergic interneuron migration [GO:0021853]; clustering of voltage-gated potassium channels [GO:0045163]; dendrite self-avoidance [GO:0070593]; establishment of protein localization to juxtaparanode region of axon [GO:0071206]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; learning [GO:0007612]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; positive regulation of protein processing [GO:0010954]; presynaptic membrane organization [GO:0097090]; protein localization to juxtaparanode region of axon [GO:0071205]; receptor internalization [GO:0031623]; regulation of astrocyte differentiation [GO:0048710]; regulation of axon diameter [GO:0031133]; regulation of neuronal synaptic plasticity [GO:0048168]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cell-cell signaling [GO:0007267]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	adult walking behavior [GO:0007628]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cerebral cortex GABAergic interneuron migration [GO:0021853]; clustering of voltage-gated potassium channels [GO:0045163]; dendrite self-avoidance [GO:0070593]; establishment of protein localization to juxtaparanode region of axon [GO:0071206]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; learning [GO:0007612]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; positive regulation of protein processing [GO:0010954]; presynaptic membrane organization [GO:0097090]; protein localization to juxtaparanode region of axon [GO:0071205]; receptor internalization [GO:0031623]; regulation of astrocyte differentiation [GO:0048710]; regulation of axon diameter [GO:0031133]; regulation of neuronal synaptic plasticity [GO:0048168]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cell death [GO:0008219]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	anchored component of postsynaptic membrane [GO:0099025]; axon [GO:0030424]; cell surface [GO:0009986]; juxtaparanode region of axon [GO:0044224]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; node of Ranvier [GO:0033268]; plasma membrane [GO:0005886]; synapse [GO:0045202]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; cell-cell adhesion mediator activity [GO:0098632]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]	cytokine activity [GO:0005125]
d2omba1_d1lk2b___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2ombb1_d3tnnd2__1												
d2ombc1_d2dm3a1__1		Metazoa		Chordata		actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; podosome [GO:0002102]; ruffle [GO:0001726]; Z disc [GO:0030018]; actin binding [GO:0003779]; cell-cell adhesion mediator activity [GO:0098632]; muscle alpha-actinin binding [GO:0051371]; actin cytoskeleton organization [GO:0030036]; axon guidance [GO:0007411]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; dendrite self-avoidance [GO:0070593]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte development [GO:0003334]		actin cytoskeleton organization [GO:0030036]; axon guidance [GO:0007411]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; dendrite self-avoidance [GO:0070593]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte development [GO:0003334]		actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; podosome [GO:0002102]; ruffle [GO:0001726]; Z disc [GO:0030018]		actin binding [GO:0003779]; cell-cell adhesion mediator activity [GO:0098632]; muscle alpha-actinin binding [GO:0051371]
d2ombc1_d4r7dl2__1		Metazoa		Chordata								
d2ombd1_d3wiil1__1												
d2omdb__d4ap8b___1		Metazoa	Aquificae	Chordata	cytosol [GO:0005829]; molybdopterin synthase activity [GO:0030366]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytosol [GO:0005829]; molybdopterin synthase complex [GO:0019008]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; molybdopterin synthase activity [GO:0030366]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor biosynthetic process [GO:0032324]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytosol [GO:0005829]	cytosol [GO:0005829]; molybdopterin synthase complex [GO:0019008]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	molybdopterin synthase activity [GO:0030366]	molybdopterin synthase activity [GO:0030366]
d2omna1_d4cl7a___1		Metazoa		Chordata		actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]		blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]
d2omna1_d4pjxg1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2omnb1_d4lcwh2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2omnb2_d3sdxa2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2omub2_d5i8da2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	apical part of cell [GO:0045177]; catenin complex [GO:0016342]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; centrosome [GO:0005813]; cochlear hair cell ribbon synapse [GO:0098683]; integral component of membrane [GO:0016021]; kinocilium [GO:0060091]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426]; synapse [GO:0045202]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; adherens junction organization [GO:0034332]; auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; post-embryonic animal organ morphogenesis [GO:0048563]; regulation of cytosolic calcium ion concentration [GO:0051480]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction organization [GO:0034332]; auditory receptor cell stereocilium organization [GO:0060088]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium ion transport [GO:0006816]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; post-embryonic animal organ morphogenesis [GO:0048563]; regulation of cytosolic calcium ion concentration [GO:0051480]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	apical part of cell [GO:0045177]; catenin complex [GO:0016342]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; centrosome [GO:0005813]; cochlear hair cell ribbon synapse [GO:0098683]; integral component of membrane [GO:0016021]; kinocilium [GO:0060091]; photoreceptor inner segment [GO:0001917]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426]; synapse [GO:0045202]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d2omva2_d2wque1__1	Metazoa		Chordata	Firmicutes	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	pathogenesis [GO:0009405]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	heparin binding [GO:0008201]; lipid binding [GO:0008289]
d2omva2_d4krma1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2omwa2_d2v70b___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; GTPase inhibitor activity [GO:0005095]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; laminin-1 binding [GO:0043237]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; Roundabout binding [GO:0048495]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; cellular response to hormone stimulus [GO:0032870]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; induction of negative chemotaxis [GO:0050929]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; pulmonary valve morphogenesis [GO:0003184]; response to cortisol [GO:0051414]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; cellular response to hormone stimulus [GO:0032870]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; induction of negative chemotaxis [GO:0050929]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; pulmonary valve morphogenesis [GO:0003184]; response to cortisol [GO:0051414]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	calcium ion binding [GO:0005509]; GTPase inhibitor activity [GO:0005095]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; laminin-1 binding [GO:0043237]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; Roundabout binding [GO:0048495]
d2omwa2_d2wqwb1__1	Metazoa		Chordata	Firmicutes	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	pathogenesis [GO:0009405]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	heparin binding [GO:0008201]; lipid binding [GO:0008289]
d2omxb2_d1ff5a1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d2omyb2_d3lnea1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d2omyb2_d5jymc1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d2omza2_d1xeca___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	collagen-containing extracellular matrix [GO:0062023]; collagen binding [GO:0005518]; collagen fibril binding [GO:0098633]; extracellular matrix binding [GO:0050840]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; glycosaminoglycan binding [GO:0005539]; protein homodimerization activity [GO:0042803]; negative regulation of angiogenesis [GO:0016525]; negative regulation of collagen fibril organization [GO:1904027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800]; positive regulation of macroautophagy [GO:0016239]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of transcription by RNA polymerase II [GO:0045944]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	negative regulation of angiogenesis [GO:0016525]; negative regulation of collagen fibril organization [GO:1904027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800]; positive regulation of macroautophagy [GO:0016239]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of transcription by RNA polymerase II [GO:0045944]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	collagen-containing extracellular matrix [GO:0062023]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	collagen binding [GO:0005518]; collagen fibril binding [GO:0098633]; extracellular matrix binding [GO:0050840]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; glycosaminoglycan binding [GO:0005539]; protein homodimerization activity [GO:0042803]
d2omzb2_d2qvfb2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d2on5a2_d1ev4d1__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	transferase activity [GO:0016740]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]; aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]	transferase activity [GO:0016740]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]
d2on5b1_d1g6wc2__1	Metazoa	Fungi	Nematoda (roundworms)	Ascomycota	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasm [GO:0005737]	transferase activity [GO:0016740]	glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]
d2on5b1_d2h66a___1	Metazoa		Nematoda (roundworms)	Apicomplexa	transferase activity [GO:0016740]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]	transferase activity [GO:0016740]	peroxiredoxin activity [GO:0051920]
d2on5c1_d4xtsa___1	Metazoa		Nematoda (roundworms)	Proteobacteria	transferase activity [GO:0016740]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]		cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cytosol [GO:0005829]	transferase activity [GO:0016740]	thioredoxin peroxidase activity [GO:0008379]
d2on5c2_d2ws2a2__1	Metazoa	Metazoa	Nematoda (roundworms)	Nematoda (roundworms)	transferase activity [GO:0016740]	transferase activity [GO:0016740]					transferase activity [GO:0016740]	transferase activity [GO:0016740]
d2on5c2_d4k0ga2__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	transferase activity [GO:0016740]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]		chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]		blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	transferase activity [GO:0016740]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]
d2on5d1_d1jlve2__1	Metazoa	Metazoa	Nematoda (roundworms)	Arthropoda	transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]					transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]
d2on5d2_d2wrte2__1	Metazoa	Metazoa	Nematoda (roundworms)	Platyhelminthes	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]				cytoplasm [GO:0005737]	transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]
d2on5e2_d5a5kv2__1	Metazoa	Viridiplantae	Nematoda (roundworms)	Streptophyta	transferase activity [GO:0016740]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	transferase activity [GO:0016740]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d2on5g1_d1xwca___1	Metazoa	Metazoa	Nematoda (roundworms)	Arthropoda	transferase activity [GO:0016740]	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]		cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; nucleus [GO:0005634]	transferase activity [GO:0016740]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]
d2on5h2_d5gstb1__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	transferase activity [GO:0016740]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]		glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]		cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	transferase activity [GO:0016740]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d2on7b2_d1xwkb1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d2on7b2_d5f05c2__1		Viridiplantae		Streptophyta		cytoplasm [GO:0005737]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]		glutathione metabolic process [GO:0006749]		cytoplasm [GO:0005737]		glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2on7d2_d2wrtc2__1		Metazoa		Platyhelminthes		cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]				cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]
d2onca2_d4dmkb1__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	hydrolase activity [GO:0016787]
d2oncd2_d4x00a___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	hydrolase activity [GO:0016787]
d2onea1_d2ps2a2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	metal ion binding [GO:0046872]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	metal ion binding [GO:0046872]
d2onga1_d1tnbh___1	Viridiplantae	Metazoa	Streptophyta	Chordata	magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]		negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]		CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d2ongb2_d3n1vf___1	Viridiplantae	Metazoa	Streptophyta	Chordata	magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]		cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2onha2_d5impd___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]					magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]
d2onhb1_d1tnuf___1	Viridiplantae	Metazoa	Streptophyta	Chordata	magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]		negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]		CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d2onke1_d3h06g___1		Metazoa	Euryarchaeota	Chordata	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; tungstate binding [GO:1901359]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	plasma membrane [GO:0005886]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]; tungstate binding [GO:1901359]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2onke1_d4pfba___1			Euryarchaeota	Fusobacteria	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; tungstate binding [GO:1901359]	metal ion binding [GO:0046872]; transmembrane transport [GO:0055085]		transmembrane transport [GO:0055085]	plasma membrane [GO:0005886]		metal ion binding [GO:0046872]; tungstate binding [GO:1901359]	metal ion binding [GO:0046872]
d2onkf__d1f2u.2__1			Euryarchaeota	Euryarchaeota	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; tungstate binding [GO:1901359]	ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; double-strand break repair [GO:0006302]		double-strand break repair [GO:0006302]	plasma membrane [GO:0005886]		metal ion binding [GO:0046872]; tungstate binding [GO:1901359]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d2onkg__d2bwjc___1		Metazoa	Euryarchaeota	Chordata	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; tungstate binding [GO:1901359]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]		ADP biosynthetic process [GO:0006172]; ATP metabolic process [GO:0046034]; dADP biosynthetic process [GO:0006173]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]	plasma membrane [GO:0005886]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]	metal ion binding [GO:0046872]; tungstate binding [GO:1901359]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d2onkg__d3d31a2__1			Euryarchaeota	Euryarchaeota	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; tungstate binding [GO:1901359]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; transmembrane transport [GO:0055085]		transmembrane transport [GO:0055085]	plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; tungstate binding [GO:1901359]	
d2onkj2_d2xxub___1		Metazoa	Euryarchaeota	Chordata	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; tungstate binding [GO:1901359]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]		behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	plasma membrane [GO:0005886]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]; tungstate binding [GO:1901359]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d2onma__d1nzze___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2onmb__d1nzxh___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2onmc__d2onpc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2onmh__d3inja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2onmh__d4zwlh___1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; glycine betaine biosynthetic process from choline [GO:0019285]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glycine betaine biosynthetic process from choline [GO:0019285]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2onnc__d1o05g___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2onng__d5n5sd___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	lactaldehyde dehydrogenase activity [GO:0008911]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	lactaldehyde dehydrogenase activity [GO:0008911]
d2onnh__d5kf0b___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2onob__d3ifhq1__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	
d2onoh__d3k2wg1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	betaine-aldehyde dehydrogenase activity [GO:0008802]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	betaine-aldehyde dehydrogenase activity [GO:0008802]
d2onoh__d4l1oa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]
d2onpa__d4h73d___1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2onpg__d4h73f___1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2onra2_d4ohna___1			Euryarchaeota	Firmicutes	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; tungstate binding [GO:1901359]				plasma membrane [GO:0005886]		metal ion binding [GO:0046872]; tungstate binding [GO:1901359]	
d2onya__d5jmqa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	methyltransferase activity [GO:0008168]; protein methylation [GO:0006479]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	protein methylation [GO:0006479]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		phenylethanolamine N-methyltransferase activity [GO:0004603]	methyltransferase activity [GO:0008168]
d2onza__d3lhdb___1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	tRNA (m1A) methyltransferase complex [GO:0031515]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	tRNA (m1A) methyltransferase complex [GO:0031515]	phenylethanolamine N-methyltransferase activity [GO:0004603]	tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]
d2oohc__d3gadb___1	Metazoa		Chordata	Apicomplexa	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	
d2oola1_d3c2wg1__1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d2oolb1_d4ijga2__1			Proteobacteria	Deinococcus-Thermus	identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d2oovb2_d1n9ed2__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; amine metabolic process [GO:0009308]; cellular response to inorganic substance [GO:0071241]; oxidation-reduction process [GO:0055114]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; cellular response to inorganic substance [GO:0071241]; oxidation-reduction process [GO:0055114]	peroxisome [GO:0005777]		aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]
d2oowb__d3mjzh___1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	
d2op2a__d1z6sb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d2op3a__d4jkjb___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; adult walking behavior [GO:0007628]; axon target recognition [GO:0007412]; axonal transport of mitochondrion [GO:0019896]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	adult walking behavior [GO:0007628]; axonal transport of mitochondrion [GO:0019896]; axon target recognition [GO:0007412]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]
d2op4l1_d1hyxl3__1	Metazoa		Chordata									
d2op4l2_d5jdeb2__1	Metazoa	Metazoa	Chordata	Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d2opba__d3kpvb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	phenylethanolamine N-methyltransferase activity [GO:0004603]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d2opba__d4o29a1__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytoplasm [GO:0005737]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]; protein repair [GO:0030091]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	protein repair [GO:0030091]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	phenylethanolamine N-methyltransferase activity [GO:0004603]	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]
d2opfa1_d4g4oa2__1			Proteobacteria	Firmicutes	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA N-glycosylase activity [GO:0019104]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [GO:0000703]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]			class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA N-glycosylase activity [GO:0019104]; endonuclease activity [GO:0004519]; oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [GO:0000703]; zinc ion binding [GO:0008270]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]
d2opga1_d2wl7a1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; protein C-terminus binding [GO:0008022]; cell adhesion [GO:0007155]; viral process [GO:0016032]	anchored component of postsynaptic density membrane [GO:0099031]; axon cytoplasm [GO:1904115]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; kinase binding [GO:0019900]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; structural constituent of postsynaptic density [GO:0098919]; anterograde axonal protein transport [GO:0099641]; cell-cell adhesion [GO:0098609]; cellular response to potassium ion [GO:0035865]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of phosphatase activity [GO:0010923]; neuronal ion channel clustering [GO:0045161]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; retrograde axonal protein transport [GO:0099642]; sensory perception of pain [GO:0019233]	cell adhesion [GO:0007155]; viral process [GO:0016032]	anterograde axonal protein transport [GO:0099641]; cell-cell adhesion [GO:0098609]; cellular response to potassium ion [GO:0035865]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of phosphatase activity [GO:0010923]; neuronal ion channel clustering [GO:0045161]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; retrograde axonal protein transport [GO:0099642]; sensory perception of pain [GO:0019233]	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	anchored component of postsynaptic density membrane [GO:0099031]; axon cytoplasm [GO:1904115]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]	protein C-terminus binding [GO:0008022]	kinase binding [GO:0019900]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; structural constituent of postsynaptic density [GO:0098919]
d2opsa3_d4iljb1__1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]; generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]
d2oq7a__d2y86a___1	Metazoa		Chordata		histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]		chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]		histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	
d2oqea3_d1d6za2__1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	periplasmic space [GO:0042597]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	peroxisome [GO:0005777]	periplasmic space [GO:0042597]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d2oqeb2_d1dyub2__1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	periplasmic space [GO:0042597]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	peroxisome [GO:0005777]	periplasmic space [GO:0042597]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d2oqia2_d5syma___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; carboxylic ester hydrolase activity [GO:0052689]; lipase activity [GO:0016298]; lysophospholipase activity [GO:0004622]; palmitoyl-(protein) hydrolase activity [GO:0008474]; fatty acid metabolic process [GO:0006631]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; protein depalmitoylation [GO:0002084]; regulation of nitric-oxide synthase activity [GO:0050999]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	fatty acid metabolic process [GO:0006631]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; protein depalmitoylation [GO:0002084]; regulation of nitric-oxide synthase activity [GO:0050999]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	carboxylic ester hydrolase activity [GO:0052689]; lipase activity [GO:0016298]; lysophospholipase activity [GO:0004622]; palmitoyl-(protein) hydrolase activity [GO:0008474]
d2oqib2_d2ajdc2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d2oqic2_d5tnna___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	hydrolase activity [GO:0016787]
d2oqjb1_d1mcqb1__1												
d2oqjb1_d1rzih2__1												
d2oqjh1_d4z7ua2__1		Viridiplantae		Streptophyta		nutrient reservoir activity [GO:0045735]						nutrient reservoir activity [GO:0045735]
d2oqjh2_d1ck0l1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2oqra1_d1ab5b___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; pathogenesis [GO:0009405]; regulation of phosphate metabolic process [GO:0019220]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	pathogenesis [GO:0009405]; regulation of phosphate metabolic process [GO:0019220]; regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d2oqua__d3gy5a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2oqvb2_d1uk9a___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	hydrolase activity [GO:0016787]
d2oqya2_d3ozme2__1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]		cellular amino acid catabolic process [GO:0009063]			lyase activity [GO:0016829]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2oqyb2_d2xsxa2__1		Metazoa	Firmicutes	Chordata	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; response to drug [GO:0042493]; skeletal muscle tissue regeneration [GO:0043403]		aging [GO:0007568]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; response to drug [GO:0042493]; skeletal muscle tissue regeneration [GO:0043403]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d2oqyc1_d3thuc1__1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]		carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			lyase activity [GO:0016829]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d2oqyc1_d5eu9a1__1		Metazoa	Firmicutes	Chordata	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2oqye1_d2akza2__1		Metazoa	Firmicutes	Chordata	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2oqyg1_d4zcwb1__1		Metazoa	Firmicutes	Chordata	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2oqyh1_d2pu0a2__1			Firmicutes		lyase activity [GO:0016829]; metal ion binding [GO:0046872]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2or1r__d1zuga___1					DNA binding [GO:0003677]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]		regulation of transcription, DNA-templated [GO:0006355]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2or2b__d4ptda___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]
d2or7b1_d1uach1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ferritin receptor activity [GO:0070287]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	iron ion transport [GO:0006826]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	ferritin receptor activity [GO:0070287]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2or8a1_d2fx8j1__1	Metazoa		Chordata		cell surface [GO:0009986]; integral component of membrane [GO:0016021]; phosphatidylserine binding [GO:0001786]; positive regulation of mast cell activation [GO:0033005]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	positive regulation of mast cell activation [GO:0033005]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	phosphatidylserine binding [GO:0001786]	structural molecule activity [GO:0005198]
d2or9i1_d4aizc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	extracellular region [GO:0005576]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	extracellular region [GO:0005576]		
d2oraa1_d2uzqe2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5S rRNA binding [GO:0008097]; thiosulfate sulfurtransferase activity [GO:0004792]; rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; transsulfuration [GO:0019346]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; transsulfuration [GO:0019346]	cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	5S rRNA binding [GO:0008097]; thiosulfate sulfurtransferase activity [GO:0004792]	phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]
d2orbl2_d1k4da1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2orbl2_d2ianl1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2orbm2_d2j4wl1__1	Metazoa		Chordata	Apicomplexa	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	membrane [GO:0016020]; pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	pathogenesis [GO:0009405]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	membrane [GO:0016020]		
d2orjb1_d3pbfa2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]
d2orkb1_d1ypua___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d2orxa1_d2qqia1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome [GO:0005769]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; sorting endosome [GO:0097443]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; axon extension involved in axon guidance [GO:0048846]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sensory neuron axon guidance [GO:0097374]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]; coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sensory neuron axon guidance [GO:0097374]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	axon [GO:0030424]; cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome [GO:0005769]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; sorting endosome [GO:0097443]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]	GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]	coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d2orxa2_d5jgia1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome [GO:0005769]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; sorting endosome [GO:0097443]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; axon extension involved in axon guidance [GO:0048846]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sensory neuron axon guidance [GO:0097374]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]; coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sensory neuron axon guidance [GO:0097374]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	axon [GO:0030424]; cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome [GO:0005769]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; sorting endosome [GO:0097443]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]	GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]	coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d2os9a1_d4ak8d___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d2os9a1_d5f2qd___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; negative regulation of cell growth [GO:0030308]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	negative regulation of cell growth [GO:0030308]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2os9c1_d1yu4c2__1	Metazoa		Chordata		clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	virus tail, fiber [GO:0098024]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	
d2osaa__d1ow3a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; ephrin receptor binding [GO:0046875]; GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; SH3/SH2 adaptor activity [GO:0005070]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; motor neuron axon guidance [GO:0008045]; regulation of axonogenesis [GO:0050770]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; cadherin binding [GO:0045296]; GTPase activator activity [GO:0005096]; Rab GTPase binding [GO:0017137]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; endosomal transport [GO:0016197]; negative regulation of endocytic recycling [GO:2001136]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; small GTPase mediated signal transduction [GO:0007264]; transferrin transport [GO:0033572]	ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; motor neuron axon guidance [GO:0008045]; regulation of axonogenesis [GO:0050770]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]	endosomal transport [GO:0016197]; negative regulation of endocytic recycling [GO:2001136]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; small GTPase mediated signal transduction [GO:0007264]; transferrin transport [GO:0033572]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]	ephrin receptor binding [GO:0046875]; GTPase activator activity [GO:0005096]; metal ion binding [GO:0046872]; SH3/SH2 adaptor activity [GO:0005070]	cadherin binding [GO:0045296]; GTPase activator activity [GO:0005096]; Rab GTPase binding [GO:0017137]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]
d2osfa__d4hu1a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; myelin sheath [GO:0043209]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; myelin sheath [GO:0043209]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2oslb1_d5xf1d2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	host cell cytoplasm [GO:0030430]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	lysozyme activity [GO:0003796]
d2oslb2_d1i3rb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2oslb2_d1mjjl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2osll1_d4r7db2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2ospa1_d4uu9h___1		Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]		activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]		chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d2ospa1_d5xajl1__1												
d2ospa2_d3cvhm1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2ospa2_d4rdqn1__1		Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]; chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]		detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]		basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]		chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2ospc1_d3c60a1__1		Metazoa		Chordata		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d2otca1_d1raia1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2otcb1_d3m5ca2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]
d2otcb1_d4e2fk2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2otcc1_d1ekxa2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2otcc2_d4amud2__1			Proteobacteria	Tenericutes	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d2otce2_d7at1a2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2otch2_d2otch1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]
d2otjb1_d3d5de1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d2otjf1_d1w40a1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	cytosolic large ribosomal subunit [GO:0022625]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]
d2otle1_d2qamg2__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d2otlk1_d3df4k1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d2ou7a__d5ipja___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]; anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; manganese ion binding [GO:0030145]; protein serine/threonine kinase activity [GO:0004674]; ribosomal small subunit binding [GO:0043024]; transcription factor binding [GO:0008134]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular detoxification [GO:1990748]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan metabolic process [GO:0030212]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular detoxification [GO:1990748]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan metabolic process [GO:0030212]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561]	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; manganese ion binding [GO:0030145]; protein serine/threonine kinase activity [GO:0004674]; ribosomal small subunit binding [GO:0043024]; transcription factor binding [GO:0008134]
d2ouab__d1dit.1__1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]		acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d2ouba__d2osha___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d2ouha__d1okqa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]; activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]	signaling receptor binding [GO:0005102]
d2oulb__d2c34a1__1					cell surface [GO:0009986]; ciliary pocket [GO:0020016]; cytoplasmic vesicle [GO:0031410]; cysteine-type endopeptidase inhibitor activity [GO:0004869]				cell surface [GO:0009986]; ciliary pocket [GO:0020016]; cytoplasmic vesicle [GO:0031410]		cysteine-type endopeptidase inhibitor activity [GO:0004869]	
d2ouna1_d3hqwa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]
d2ouna1_d3ly2g___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d2ounb1_d5u7id___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d2oupa1_d5xkma___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d2ouua1_d3sl4b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d2ouva1_d1tbmb___1	Metazoa		Chordata		cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]		cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]		cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]		3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	
d2ouvb1_d3tgea___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytosol [GO:0005829]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]
d2ov2c1_d5cj2b___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; calcium-dependent protein binding [GO:0048306]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cerebral cortex GABAergic interneuron development [GO:0021894]; establishment or maintenance of cell polarity [GO:0007163]; homeostasis of number of cells within a tissue [GO:0048873]; intracellular signal transduction [GO:0035556]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of neuron maturation [GO:0014041]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; synaptic transmission, GABAergic [GO:0051932]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cerebral cortex GABAergic interneuron development [GO:0021894]; establishment or maintenance of cell polarity [GO:0007163]; homeostasis of number of cells within a tissue [GO:0048873]; intracellular signal transduction [GO:0035556]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of neuron maturation [GO:0014041]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; synaptic transmission, GABAergic [GO:0051932]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cell cortex [GO:0005938]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	calcium-dependent protein binding [GO:0048306]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein kinase binding [GO:0019901]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2ov2d1_d3qb6b___1	Metazoa		Chordata		cell cortex [GO:0005938]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; calcium-dependent protein binding [GO:0048306]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cerebral cortex GABAergic interneuron development [GO:0021894]; establishment or maintenance of cell polarity [GO:0007163]; homeostasis of number of cells within a tissue [GO:0048873]; intracellular signal transduction [GO:0035556]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of neuron maturation [GO:0014041]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; synaptic transmission, GABAergic [GO:0051932]		actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cerebral cortex GABAergic interneuron development [GO:0021894]; establishment or maintenance of cell polarity [GO:0007163]; homeostasis of number of cells within a tissue [GO:0048873]; intracellular signal transduction [GO:0035556]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of neuron maturation [GO:0014041]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; synaptic transmission, GABAergic [GO:0051932]		cell cortex [GO:0005938]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]		calcium-dependent protein binding [GO:0048306]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein kinase binding [GO:0019901]	
d2ov2g1_d3sbda1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; calcium-dependent protein binding [GO:0048306]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cerebral cortex GABAergic interneuron development [GO:0021894]; establishment or maintenance of cell polarity [GO:0007163]; homeostasis of number of cells within a tissue [GO:0048873]; intracellular signal transduction [GO:0035556]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of neuron maturation [GO:0014041]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; synaptic transmission, GABAergic [GO:0051932]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; histone deacetylase binding [GO:0042826]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cell-matrix adhesion [GO:0007160]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cerebral cortex GABAergic interneuron development [GO:0021894]; establishment or maintenance of cell polarity [GO:0007163]; homeostasis of number of cells within a tissue [GO:0048873]; intracellular signal transduction [GO:0035556]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of neuron maturation [GO:0014041]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; synaptic transmission, GABAergic [GO:0051932]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cell cortex [GO:0005938]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filamentous actin [GO:0031941]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]	calcium-dependent protein binding [GO:0048306]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein kinase binding [GO:0019901]	ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; histone deacetylase binding [GO:0042826]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]
d2ov3a__d1g21b___1			Cyanobacteria	Proteobacteria	metal ion binding [GO:0046872]; metal ion transport [GO:0030001]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	metal ion transport [GO:0030001]	nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]	metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2ovkb__d2m49b___1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]		astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d2ovpb2_d3eg6a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; SCF ubiquitin ligase complex [GO:0019005]; cyclin binding [GO:0030332]; identical protein binding [GO:0042802]; phosphothreonine residue binding [GO:0050816]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lipid homeostasis [GO:0055088]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; post-translational protein modification [GO:0043687]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; regulation of lipid storage [GO:0010883]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lipid homeostasis [GO:0055088]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; post-translational protein modification [GO:0043687]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; regulation of lipid storage [GO:0010883]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; SCF ubiquitin ligase complex [GO:0019005]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	cyclin binding [GO:0030332]; identical protein binding [GO:0042802]; phosphothreonine residue binding [GO:0050816]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]
d2ovqb2_d2h6na___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; SCF ubiquitin ligase complex [GO:0019005]; cyclin binding [GO:0030332]; identical protein binding [GO:0042802]; phosphothreonine residue binding [GO:0050816]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lipid homeostasis [GO:0055088]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; post-translational protein modification [GO:0043687]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; regulation of lipid storage [GO:0010883]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lipid homeostasis [GO:0055088]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; post-translational protein modification [GO:0043687]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; regulation of lipid storage [GO:0010883]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; SCF ubiquitin ligase complex [GO:0019005]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	cyclin binding [GO:0030332]; identical protein binding [GO:0042802]; phosphothreonine residue binding [GO:0050816]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]
d2ovwb__d3l2yj___1	Fungi	Metazoa	Ascomycota	Chordata	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cellulose catabolic process [GO:0030245]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	cellulase activity [GO:0008810]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d2ovwc__d4ipma1__1	Fungi	Metazoa	Ascomycota	Arthropoda	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]			cellulase activity [GO:0008810]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; metal ion binding [GO:0046872]
d2ovwd__d1vlna___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cellulose catabolic process [GO:0030245]				cellulase activity [GO:0008810]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2ovxa__d1kuga___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]		collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]
d2ovxb__d4jp4b___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d2ovzb__d5js3e___1	Metazoa		Chordata	Firmicutes	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]		collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d2ow0a__d2ayka___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d2ow0a__d4tlna___1	Metazoa		Chordata	Firmicutes	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]		collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d2ow1b__d4xbhb___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	axon [GO:0030424]; brush border [GO:0005903]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; integral component of membrane [GO:0016021]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; metalloendopeptidase activity [GO:0004222]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270]; amyloid-beta metabolic process [GO:0050435]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; peptide metabolic process [GO:0006518]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	amyloid-beta metabolic process [GO:0050435]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; peptide metabolic process [GO:0006518]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	axon [GO:0030424]; brush border [GO:0005903]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; integral component of membrane [GO:0016021]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270]
d2ow2a__d5wvub___1	Metazoa		Chordata	Deinococcus-Thermus	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]		collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2ow7a3_d1k1xa3__1	Metazoa		Arthropoda	Euryarchaeota	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]
d2ow8j1_d1i96e1__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2ow8j1_d2ba0g1__1				Euryarchaeota		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]		RNA catabolic process [GO:0006401]		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]		3'-5'-exoribonuclease activity [GO:0000175]
d2ow9a__d4pksa2__1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d2ow9b__d3l0tb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d2owdb__d1rpta___1		Metazoa	Deinococcus-Thermus	Chordata	catalytic activity [GO:0003824]	apical part of cell [GO:0045177]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; lysosomal membrane [GO:0005765]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; choline binding [GO:0033265]; protein homodimerization activity [GO:0042803]; dephosphorylation [GO:0016311]		dephosphorylation [GO:0016311]		apical part of cell [GO:0045177]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; lysosomal membrane [GO:0005765]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]	catalytic activity [GO:0003824]	5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; choline binding [GO:0033265]; protein homodimerization activity [GO:0042803]
d2owdb__d2p79a___1			Deinococcus-Thermus	Deinococcus-Thermus	catalytic activity [GO:0003824]	catalytic activity [GO:0003824]					catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d2owea__d1nd6b___1		Metazoa	Deinococcus-Thermus	Chordata	catalytic activity [GO:0003824]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]; adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]		adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]		azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	catalytic activity [GO:0003824]	5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]
d2owga__d2pcga___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2owha__d4eq1a1__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]; aryl hydrocarbon receptor binding [GO:0017162]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; nuclear receptor activity [GO:0004879]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; cell differentiation [GO:0030154]; embryonic placenta development [GO:0001892]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; xenobiotic metabolic process [GO:0006805]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	cell differentiation [GO:0030154]; embryonic placenta development [GO:0001892]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; xenobiotic metabolic process [GO:0006805]	integral component of plasma membrane [GO:0005887]	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	aryl hydrocarbon receptor binding [GO:0017162]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; nuclear receptor activity [GO:0004879]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]
d2owia1_d1fqkb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to forskolin [GO:1904322]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of protein localization to cell cortex [GO:1904778]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of mitotic spindle organization [GO:0060236]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cell cortex region [GO:0099738]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]	GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d2ox4a1_d3q4df1__1			Proteobacteria	Bacteroidetes	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]		peptide metabolic process [GO:0006518]			metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d2ox4b2_d5boeb2__1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]		glycolytic process [GO:0006096]; pathogenesis [GO:0009405]		cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2ox4c1_d2akzb2__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2ox4d1_d2rdxb1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2ox4d2_d4e6mh2__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2ox4e2_d1jdfd1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]		D-glucarate catabolic process [GO:0042838]			metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d2ox4f2_d1ec8d1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]		D-glucarate catabolic process [GO:0042838]			metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d2ox8b__d1sl4a___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; endocytic vesicle membrane [GO:0030666]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; galactose binding [GO:0005534]; low-density lipoprotein particle binding [GO:0030169]; metal ion binding [GO:0046872]; scavenger receptor activity [GO:0005044]; signaling pattern recognition receptor activity [GO:0008329]; carbohydrate mediated signaling [GO:0009756]; cellular response to exogenous dsRNA [GO:0071360]; defense response [GO:0006952]; innate immune response [GO:0045087]; phagocytosis, recognition [GO:0006910]; positive regulation of cell adhesion molecule production [GO:0060355]; protein homooligomerization [GO:0051260]; receptor-mediated endocytosis [GO:0006898]; regulation of immune response [GO:0050776]; toll-like receptor 3 signaling pathway [GO:0034138]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	carbohydrate mediated signaling [GO:0009756]; cellular response to exogenous dsRNA [GO:0071360]; defense response [GO:0006952]; innate immune response [GO:0045087]; phagocytosis, recognition [GO:0006910]; positive regulation of cell adhesion molecule production [GO:0060355]; protein homooligomerization [GO:0051260]; receptor-mediated endocytosis [GO:0006898]; regulation of immune response [GO:0050776]; toll-like receptor 3 signaling pathway [GO:0034138]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	collagen trimer [GO:0005581]; endocytic vesicle membrane [GO:0030666]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	galactose binding [GO:0005534]; low-density lipoprotein particle binding [GO:0030169]; metal ion binding [GO:0046872]; scavenger receptor activity [GO:0005044]; signaling pattern recognition receptor activity [GO:0008329]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]
d2ox9a__d1wmza___1	Metazoa	Metazoa	Chordata	Echinodermata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; low-density lipoprotein particle binding [GO:0030169]; metal ion binding [GO:0046872]; signaling pattern recognition receptor activity [GO:0008329]; transmembrane signaling receptor activity [GO:0004888]; cellular response to exogenous dsRNA [GO:0071360]; immune response [GO:0006955]; phagocytosis, recognition [GO:0006910]; positive regulation of cell adhesion molecule production [GO:0060355]; toll-like receptor 3 signaling pathway [GO:0034138]	metal ion binding [GO:0046872]	cellular response to exogenous dsRNA [GO:0071360]; immune response [GO:0006955]; phagocytosis, recognition [GO:0006910]; positive regulation of cell adhesion molecule production [GO:0060355]; toll-like receptor 3 signaling pathway [GO:0034138]		collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; integral component of membrane [GO:0016021]		carbohydrate binding [GO:0030246]; low-density lipoprotein particle binding [GO:0030169]; metal ion binding [GO:0046872]; signaling pattern recognition receptor activity [GO:0008329]; transmembrane signaling receptor activity [GO:0004888]	metal ion binding [GO:0046872]
d2oxcb__d2hjvb___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Gemini of coiled bodies [GO:0097504]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription repressor complex [GO:0090571]; SMN complex [GO:0032797]; SMN-Sm protein complex [GO:0034719]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; histone deacetylase binding [GO:0042826]; protein binding, bridging [GO:0030674]; protein domain specific binding [GO:0019904]; repressing transcription factor binding [GO:0070491]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; import into nucleus [GO:0051170]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oogenesis [GO:0048477]; positive regulation of apoptotic process [GO:0043065]; regulation of steroid biosynthetic process [GO:0050810]; RNA processing [GO:0006396]; spliceosomal snRNP assembly [GO:0000387]; spliceosomal tri-snRNP complex assembly [GO:0000244]	cytosol [GO:0005829]; 3'-5' RNA helicase activity [GO:0034458]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; RNA strand annealing activity [GO:0033592]; ribosomal large subunit assembly [GO:0000027]	import into nucleus [GO:0051170]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oogenesis [GO:0048477]; positive regulation of apoptotic process [GO:0043065]; regulation of steroid biosynthetic process [GO:0050810]; RNA processing [GO:0006396]; spliceosomal snRNP assembly [GO:0000387]; spliceosomal tri-snRNP complex assembly [GO:0000244]	ribosomal large subunit assembly [GO:0000027]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Gemini of coiled bodies [GO:0097504]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription repressor complex [GO:0090571]; SMN complex [GO:0032797]; SMN-Sm protein complex [GO:0034719]	cytosol [GO:0005829]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; histone deacetylase binding [GO:0042826]; protein binding, bridging [GO:0030674]; protein domain specific binding [GO:0019904]; repressing transcription factor binding [GO:0070491]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]	3'-5' RNA helicase activity [GO:0034458]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; RNA strand annealing activity [GO:0033592]
d2oxga__d1jmxa3__1			Proteobacteria	Proteobacteria		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]						electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2oxgz__d2p5pa___1			Proteobacteria			cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; peptidase activity [GO:0008233]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive regulation of viral genome replication [GO:0045070]; RNA 5'-cap (guanine-N7)-methylation [GO:0106005]; RNA stabilization [GO:0043489]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive regulation of viral genome replication [GO:0045070]; RNA 5'-cap (guanine-N7)-methylation [GO:0106005]; RNA stabilization [GO:0043489]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; peptidase activity [GO:0008233]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2oxqb1_d5hptc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; SMAD binding [GO:0046332]; TPR domain binding [GO:0030911]; ubiquitin-protein transferase activity [GO:0004842]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of glucocorticoid metabolic process [GO:0031943]; ubiquitin-dependent SMAD protein catabolic process [GO:0030579]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of glucocorticoid metabolic process [GO:0031943]; ubiquitin-dependent SMAD protein catabolic process [GO:0030579]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]	Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; SMAD binding [GO:0046332]; TPR domain binding [GO:0030911]; ubiquitin-protein transferase activity [GO:0004842]	protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d2oxra2_d5a4jc___1			Euryarchaeota	Firmicutes	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; tetrahydrofolate interconversion [GO:0035999]		tetrahydrofolate interconversion [GO:0035999]			GTP binding [GO:0005525]; hydrolase activity [GO:0016787]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]
d2oxta__d1uirb___1				Deinococcus-Thermus	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; spermine synthase activity [GO:0016768]; thermospermine synthase activity [GO:0010487]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]	agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; spermine synthase activity [GO:0016768]; thermospermine synthase activity [GO:0010487]
d2oxtd__d1orha___1		Metazoa		Chordata	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; membrane [GO:0016020]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; [cytochrome c]-arginine N-methyltransferase activity [GO:0016275]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; histone-arginine N-methyltransferase activity [GO:0008469]; identical protein binding [GO:0042802]; methyl-CpG binding [GO:0008327]; protein methyltransferase activity [GO:0008276]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; snoRNP binding [GO:0030519]; histone H4-R3 methylation [GO:0043985]; liver regeneration [GO:0097421]; negative regulation of megakaryocyte differentiation [GO:0045653]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; peptidyl-arginine omega-N-methylation [GO:0035247]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hemoglobin biosynthetic process [GO:0046985]; positive regulation of p38MAPK cascade [GO:1900745]; protein homooligomerization [GO:0051260]; protein methylation [GO:0006479]; regulation of megakaryocyte differentiation [GO:0045652]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	histone H4-R3 methylation [GO:0043985]; liver regeneration [GO:0097421]; negative regulation of megakaryocyte differentiation [GO:0045653]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; peptidyl-arginine omega-N-methylation [GO:0035247]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hemoglobin biosynthetic process [GO:0046985]; positive regulation of p38MAPK cascade [GO:1900745]; protein homooligomerization [GO:0051260]; protein methylation [GO:0006479]; regulation of megakaryocyte differentiation [GO:0045652]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytosol [GO:0005829]; membrane [GO:0016020]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]	[cytochrome c]-arginine N-methyltransferase activity [GO:0016275]; histone-arginine N-methyltransferase activity [GO:0008469]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; identical protein binding [GO:0042802]; methyl-CpG binding [GO:0008327]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; protein methyltransferase activity [GO:0008276]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; snoRNP binding [GO:0030519]
d2oxua__d2x8ya___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; sperm individualization [GO:0007291]; spermatid nucleus differentiation [GO:0007289]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; spermatid nucleus differentiation [GO:0007289]; sperm individualization [GO:0007291]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]
d2oxva__d1eria___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]
d2oxwa__d1akla2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]; negative regulation of complement activation, classical pathway [GO:0045959]; negative regulation of complement activation, lectin pathway [GO:0001869]; pathogenesis [GO:0009405]; positive regulation of sodium ion transport [GO:0010765]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	negative regulation of complement activation, classical pathway [GO:0045959]; negative regulation of complement activation, lectin pathway [GO:0001869]; pathogenesis [GO:0009405]; positive regulation of sodium ion transport [GO:0010765]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]
d2oxyb__d3juha___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; protein kinase CK2 complex [GO:0005956]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; regulation of cell cycle [GO:0051726]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]; ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; regulation of cell cycle [GO:0051726]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; nucleus [GO:0005634]; protein kinase CK2 complex [GO:0005956]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]
d2oxza__d1j36a1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; sperm individualization [GO:0007291]; spermatid nucleus differentiation [GO:0007289]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; spermatid nucleus differentiation [GO:0007289]; sperm individualization [GO:0007291]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]
d2oy0b__d3kqpa___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d2oy2a__d3keka___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d2oy2f__d4naqa2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d2oy3a__d5hrja___1	Metazoa	Metazoa	Chordata	Chordata	collagen type XI trimer [GO:0005592]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; G protein-coupled receptor binding [GO:0001664]; scavenger receptor activity [GO:0005044]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; amyloid-beta clearance [GO:0097242]; apoptotic cell clearance [GO:0043277]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; receptor-mediated endocytosis [GO:0006898]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; scavenger receptor activity [GO:0005044]; virus receptor activity [GO:0001618]; acute-phase response [GO:0006953]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; amyloid-beta clearance [GO:0097242]; apoptotic cell clearance [GO:0043277]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; receptor-mediated endocytosis [GO:0006898]	acute-phase response [GO:0006953]	collagen type XI trimer [GO:0005592]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; G protein-coupled receptor binding [GO:0001664]; scavenger receptor activity [GO:0005044]	scavenger receptor activity [GO:0005044]; virus receptor activity [GO:0001618]
d2oy4f__d2mlra___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d2oy6b__d1fw4a___1		Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]; calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]; calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]		calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]		calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]
d2oyaa1_d1o5el___1	Metazoa	Metazoa	Chordata	Chordata	collagen type XI trimer [GO:0005592]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; G protein-coupled receptor binding [GO:0001664]; scavenger receptor activity [GO:0005044]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; amyloid-beta clearance [GO:0097242]; apoptotic cell clearance [GO:0043277]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; receptor-mediated endocytosis [GO:0006898]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]; basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; amyloid-beta clearance [GO:0097242]; apoptotic cell clearance [GO:0043277]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; receptor-mediated endocytosis [GO:0006898]	basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	collagen type XI trimer [GO:0005592]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; G protein-coupled receptor binding [GO:0001664]; scavenger receptor activity [GO:0005044]	calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]
d2oyab1_d1p57a___1	Metazoa	Metazoa	Chordata	Chordata	collagen type XI trimer [GO:0005592]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; G protein-coupled receptor binding [GO:0001664]; scavenger receptor activity [GO:0005044]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; amyloid-beta clearance [GO:0097242]; apoptotic cell clearance [GO:0043277]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; receptor-mediated endocytosis [GO:0006898]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]; basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; amyloid-beta clearance [GO:0097242]; apoptotic cell clearance [GO:0043277]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; receptor-mediated endocytosis [GO:0006898]	basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	collagen type XI trimer [GO:0005592]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; G protein-coupled receptor binding [GO:0001664]; scavenger receptor activity [GO:0005044]	calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]
d2oyic1_d1z3sb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	angiogenesis [GO:0001525]; animal organ regeneration [GO:0031100]; cellular response to growth factor stimulus [GO:0071363]; germ cell development [GO:0007281]; glomerulus vasculature development [GO:0072012]; leukocyte migration [GO:0050900]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of positive chemotaxis [GO:0050928]; positive regulation of angiogenesis [GO:0045766]; response to activity [GO:0014823]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to radiation [GO:0009314]; signal transduction [GO:0007165]; Tie signaling pathway [GO:0048014]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	cell projection [GO:0042995]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]
d2oypa1_d1mpal1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2oyup1_d1mhl.1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]; chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; hydrogen peroxide catabolic process [GO:0042744]; hypochlorous acid biosynthetic process [GO:0002149]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in defense response [GO:0002679]; response to food [GO:0032094]; response to gold nanoparticle [GO:1990268]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phagocytic vesicle lumen [GO:0097013]; secretory granule [GO:0030141]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	chromatin binding [GO:0003682]; heme binding [GO:0020037]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2oz0a2_d1axxa___1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; response to cadmium ion [GO:0046686]	lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	response to cadmium ion [GO:0046686]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2oz1f__d1nu1d1__1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d2oz2a__d1g0da4__1		Metazoa		Chordata	cysteine-type endopeptidase activity [GO:0004197]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; peptide cross-linking [GO:0018149]		peptide cross-linking [GO:0018149]			cysteine-type endopeptidase activity [GO:0004197]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d2oz2c__d1ms6a___1		Metazoa		Chordata	cysteine-type endopeptidase activity [GO:0004197]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	cysteine-type endopeptidase activity [GO:0004197]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d2oz4a2_d35c8h2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ozba1_d1vq9f1__1	Metazoa		Chordata	Euryarchaeota	Cajal body [GO:0015030]; MLL1 complex [GO:0071339]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type precatalytic spliceosome [GO:0071005]; U2-type spliceosomal complex [GO:0005684]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4atac snRNP [GO:0005690]; ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; snRNP binding [GO:0070990]; U4 snRNA binding [GO:0030621]; U4atac snRNA binding [GO:0030622]; mRNA splicing, via spliceosome [GO:0000398]; ribonucleoprotein complex localization [GO:0071166]; spliceosomal tri-snRNP complex assembly [GO:0000244]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	mRNA splicing, via spliceosome [GO:0000398]; ribonucleoprotein complex localization [GO:0071166]; spliceosomal tri-snRNP complex assembly [GO:0000244]	translation [GO:0006412]	Cajal body [GO:0015030]; MLL1 complex [GO:0071339]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type precatalytic spliceosome [GO:0071005]; U2-type spliceosomal complex [GO:0005684]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4atac snRNP [GO:0005690]; U4 snRNP [GO:0005687]	ribosome [GO:0005840]	ribonucleoprotein complex binding [GO:0043021]; RNA binding [GO:0003723]; snRNP binding [GO:0070990]; U4atac snRNA binding [GO:0030622]; U4 snRNA binding [GO:0030621]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2ozfa1_d2v1wb___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]; beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendritic spine [GO:0043197]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; filamentous actin [GO:0031941]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic membrane [GO:0045211]; recycling endosome lumen [GO:0034777]; recycling endosome membrane [GO:0055038]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; excitatory chemical synaptic transmission [GO:0098976]; heart development [GO:0007507]; muscle structure development [GO:0061061]	actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein-containing complex assembly [GO:0065003]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; excitatory chemical synaptic transmission [GO:0098976]; heart development [GO:0007507]; muscle structure development [GO:0061061]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendritic spine [GO:0043197]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; filamentous actin [GO:0031941]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic membrane [GO:0045211]; recycling endosome lumen [GO:0034777]; recycling endosome membrane [GO:0055038]; stress fiber [GO:0001725]; Z disc [GO:0030018]	beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]	actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d2ozlb1_d1x7zb1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]
d2ozlc2_d1x7wb1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]
d2ozna1_d4uypc1__1			Firmicutes	Firmicutes	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	polysaccharide catabolic process [GO:0000272]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2ozqa__d3np1a___1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	vasodilation [GO:0042311]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]
d2ozra__d4pkva2__1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d2ozrb__d4pkwa2__1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d2ozrg__d1ka2a___1	Metazoa		Chordata	Euryarchaeota	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cobalt ion binding [GO:0050897]; metallocarboxypeptidase activity [GO:0004181]; proteolysis [GO:0006508]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	proteolysis [GO:0006508]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	cobalt ion binding [GO:0050897]; metallocarboxypeptidase activity [GO:0004181]
d2ozwa__d1xdpb2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; calcium channel inhibitor activity [GO:0019855]; ion channel binding [GO:0044325]; protein histidine phosphatase activity [GO:0101006]; negative regulation of ATP citrate synthase activity [GO:2000984]; negative regulation of lyase activity [GO:0051350]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-histidine dephosphorylation [GO:0035971]; positive regulation of cell motility [GO:2000147]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein dephosphorylation [GO:0006470]; regulation of actin cytoskeleton reorganization [GO:2000249]	cytosol [GO:0005829]; periplasmic side of cell outer membrane [GO:0031241]; plasma membrane [GO:0005886]; polyphosphate kinase complex [GO:0009358]; ATP binding [GO:0005524]; diphosphotransferase activity [GO:0016778]; metal ion binding [GO:0046872]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; polyphosphate kinase activity [GO:0008976]; polyphosphate:AMP phosphotransferase activity [GO:0043751]; ATP generation from ADP [GO:0006757]; polyphosphate biosynthetic process [GO:0006799]; protein autophosphorylation [GO:0046777]	negative regulation of ATP citrate synthase activity [GO:2000984]; negative regulation of lyase activity [GO:0051350]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-histidine dephosphorylation [GO:0035971]; positive regulation of cell motility [GO:2000147]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein dephosphorylation [GO:0006470]; regulation of actin cytoskeleton reorganization [GO:2000249]	ATP generation from ADP [GO:0006757]; polyphosphate biosynthetic process [GO:0006799]; protein autophosphorylation [GO:0046777]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; periplasmic side of cell outer membrane [GO:0031241]; plasma membrane [GO:0005886]; polyphosphate kinase complex [GO:0009358]	calcium channel inhibitor activity [GO:0019855]; ion channel binding [GO:0044325]; protein histidine phosphatase activity [GO:0101006]	ATP binding [GO:0005524]; diphosphotransferase activity [GO:0016778]; metal ion binding [GO:0046872]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; polyphosphate:AMP phosphotransferase activity [GO:0043751]; polyphosphate kinase activity [GO:0008976]
d2p02a2_d5t8sb2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]
d2p02a3_d5a1ia2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d2p0ja__d1bhma___1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; type II site-specific deoxyribonuclease activity [GO:0009036]
d2p19c__d1tt8a___1			Actinobacteria	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cytosol [GO:0005829]; chorismate lyase activity [GO:0008813]; pyruvate biosynthetic process [GO:0042866]; ubiquinone biosynthetic process [GO:0006744]		pyruvate biosynthetic process [GO:0042866]; ubiquinone biosynthetic process [GO:0006744]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	chorismate lyase activity [GO:0008813]
d2p1da__d4dm3a___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d2p1yc2_d3ta3c1__1	Metazoa	Metazoa	Chordata	Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2p1yc2_d4l3ca2__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2p1ye2_d3nh7l2__1	Metazoa	Metazoa	Chordata	Chordata		dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]		BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; dorsal aorta morphogenesis [GO:0035912]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]		dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]
d2p24a1_d1gm3l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]		adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]	
d2p24a2_d5ksbb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]	
d2p2ga1_d2otcd1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]
d2p2gb1_d3l06a1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]
d2p2gb1_d4kgza2__1			Actinobacteria		cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]		arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]		cytoplasm [GO:0005737]		amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	
d2p2gc1_d4at1c1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2p2gc1_d4jqoc1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d2p2gd1_d1rahc2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2p2lc__d1lb1f___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; histone deacetylase binding [GO:0042826]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cell-matrix adhesion [GO:0007160]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; histone deacetylase binding [GO:0042826]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d2p2oa__d3bssa___1			Firmicutes	Proteobacteria	maltose O-acetyltransferase activity [GO:0008925]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; protein N-linked glycosylation via asparagine [GO:0018279]		protein N-linked glycosylation via asparagine [GO:0018279]			maltose O-acetyltransferase activity [GO:0008925]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2p2ob__d3gvdb1__1			Firmicutes	Proteobacteria	maltose O-acetyltransferase activity [GO:0008925]	cytoplasm [GO:0005737]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]		cysteine biosynthetic process from serine [GO:0006535]		cytoplasm [GO:0005737]	maltose O-acetyltransferase activity [GO:0008925]	serine O-acetyltransferase activity [GO:0009001]
d2p2oc__d2v0ka2__1			Firmicutes	Proteobacteria	maltose O-acetyltransferase activity [GO:0008925]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]	maltose O-acetyltransferase activity [GO:0008925]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d2p2oe__d4hzca___1			Firmicutes	Proteobacteria	maltose O-acetyltransferase activity [GO:0008925]	cytoplasm [GO:0005737]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]		cysteine biosynthetic process from serine [GO:0006535]		cytoplasm [GO:0005737]	maltose O-acetyltransferase activity [GO:0008925]	serine O-acetyltransferase activity [GO:0009001]
d2p2xa__d1wngb___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2p2ya__d4pgmb___1		Fungi	Deinococcus-Thermus	Ascomycota	catalytic activity [GO:0003824]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]	phosphoglycerate mutase activity [GO:0004619]
d2p2zb__d1ebba___1			Deinococcus-Thermus	Firmicutes	catalytic activity [GO:0003824]						catalytic activity [GO:0003824]	
d2p31a__d5a5km1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; catalase activity [GO:0004096]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cellular response to oxidative stress [GO:0034599]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	catalase activity [GO:0004096]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d2p39a__d3ltqa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; growth factor activity [GO:0008083]; type 1 fibroblast growth factor receptor binding [GO:0005105]; cell differentiation [GO:0030154]; cellular phosphate ion homeostasis [GO:0030643]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-6 [GO:0071354]; cellular response to leptin stimulus [GO:0044320]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to vitamin D [GO:0071305]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of bone mineralization [GO:0030502]; negative regulation of hormone secretion [GO:0046888]; negative regulation of osteoblast differentiation [GO:0045668]; phosphate ion homeostasis [GO:0055062]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vitamin D 24-hydroxylase activity [GO:0010980]; post-translational protein modification [GO:0043687]; regulation of phosphate transport [GO:0010966]; response to magnesium ion [GO:0032026]; response to sodium phosphate [GO:1904383]; vitamin D catabolic process [GO:0042369]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell differentiation [GO:0030154]; cellular phosphate ion homeostasis [GO:0030643]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-6 [GO:0071354]; cellular response to leptin stimulus [GO:0044320]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to vitamin D [GO:0071305]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of bone mineralization [GO:0030502]; negative regulation of hormone secretion [GO:0046888]; negative regulation of osteoblast differentiation [GO:0045668]; phosphate ion homeostasis [GO:0055062]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vitamin D 24-hydroxylase activity [GO:0010980]; post-translational protein modification [GO:0043687]; regulation of phosphate transport [GO:0010966]; response to magnesium ion [GO:0032026]; response to sodium phosphate [GO:1904383]; vitamin D catabolic process [GO:0042369]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	growth factor activity [GO:0008083]; type 1 fibroblast growth factor receptor binding [GO:0005105]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d2p3ba__d1zlfb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2p3ba__d4y5ga___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2p3da__d2p4ja___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d2p3db__d4ll3b___1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2p3la__d1rjeb1__1		Fungi		Ascomycota	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; C-terminal protein methylation [GO:0006481]; cellular protein-containing complex assembly [GO:0034622]; regulation of autophagy [GO:0010506]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cellular protein-containing complex assembly [GO:0034622]; C-terminal protein methylation [GO:0006481]; regulation of autophagy [GO:0010506]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]
d2p3ra4_d5f0xa2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]		ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d2p3rb3_d3h3oo1__1				Firmicutes		ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]		glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]				ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d2p3rb3_d3tu5a2__1		Metazoa		Chordata		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]		actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2p3rb4_d4f9oa2__1		Metazoa		Chordata		cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]		canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]		cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d2p3rd3_d3ue5a2__1		Metazoa		Chordata		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]		actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2p40a__d3pt9a3__1		Metazoa		Chordata	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; heterochromatin [GO:0000792]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; chromatin binding [GO:0003682]; DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates [GO:0051718]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; methyl-CpG binding [GO:0008327]; methyltransferase activity [GO:0008168]; promoter-specific chromatin binding [GO:1990841]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular response to amino acid stimulus [GO:0071230]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chromatin organization [GO:0006325]; DNA hypermethylation [GO:0044026]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation on cytosine [GO:0032776]; DNA methylation on cytosine within a CG sequence [GO:0010424]; gene silencing [GO:0016458]; maintenance of DNA methylation [GO:0010216]; negative regulation of gene expression [GO:0010629]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular associated smooth muscle cell apoptotic process [GO:1905460]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; response to drug [GO:0042493]; S-adenosylmethionine metabolic process [GO:0046500]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cellular response to amino acid stimulus [GO:0071230]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chromatin organization [GO:0006325]; DNA hypermethylation [GO:0044026]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation on cytosine [GO:0032776]; DNA methylation on cytosine within a CG sequence [GO:0010424]; gene silencing [GO:0016458]; maintenance of DNA methylation [GO:0010216]; negative regulation of gene expression [GO:0010629]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular associated smooth muscle cell apoptotic process [GO:1905460]; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905931]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; response to drug [GO:0042493]; S-adenosylmethionine metabolic process [GO:0046500]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; heterochromatin [GO:0000792]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	chromatin binding [GO:0003682]; DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates [GO:0051718]; DNA binding [GO:0003677]; DNA-methyltransferase activity [GO:0009008]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; methyl-CpG binding [GO:0008327]; methyltransferase activity [GO:0008168]; promoter-specific chromatin binding [GO:1990841]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2p48a__d5ar6a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d2p4ad__d4u3xa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2p4ka1_d1ap6a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2p4kb1_d1luvb1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2p4kb1_d4gung1__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2p4kb2_d2awpa2__1	Metazoa		Chordata	Apicomplexa	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2p4kc1_d2nybd1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]
d2p4kd1_d3js4b1__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2p4qa1_d3ckya1__1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; cellular response to oxidative stress [GO:0034599]; D-gluconate catabolic process [GO:0046177]; pentose-phosphate shunt, oxidative branch [GO:0009051]	2-hydroxymethylglutarate dehydrogenase activity [GO:0043718]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; cofactor catabolic process [GO:0051187]	cellular response to oxidative stress [GO:0034599]; D-gluconate catabolic process [GO:0046177]; pentose-phosphate shunt, oxidative branch [GO:0009051]	cofactor catabolic process [GO:0051187]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]	2-hydroxymethylglutarate dehydrogenase activity [GO:0043718]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2p4sa__d3qpbh___1	Metazoa		Arthropoda	Firmicutes	cytoplasm [GO:0005737]; purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	purine-nucleoside phosphorylase activity [GO:0004731]	uridine phosphorylase activity [GO:0004850]
d2p4ub__d2wmye___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; sarcolemma [GO:0042383]; acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]			cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; sarcolemma [GO:0042383]		acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d2p4ud__d1z2ea___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; sarcolemma [GO:0042383]; acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]	cytoplasm [GO:0005737]; arsenate reductase (thioredoxin) activity [GO:0030612]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]		response to arsenic-containing substance [GO:0046685]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; sarcolemma [GO:0042383]	cytoplasm [GO:0005737]	acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]	arsenate reductase (thioredoxin) activity [GO:0030612]; protein tyrosine phosphatase activity [GO:0004725]
d2p4va1_d1grja1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; DNA-templated transcription, elongation [GO:0006354]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of mRNA cleavage [GO:0031439]; regulation of DNA-templated transcription, elongation [GO:0032784]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; DNA-templated transcription, elongation [GO:0006354]; regulation of DNA-templated transcription, elongation [GO:0032784]	DNA-templated transcription, elongation [GO:0006354]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of mRNA cleavage [GO:0031439]; regulation of DNA-templated transcription, elongation [GO:0032784]	DNA-templated transcription, elongation [GO:0006354]; regulation of DNA-templated transcription, elongation [GO:0032784]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]	bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]
d2p4vb1_d2f23a1__1			Proteobacteria	Deinococcus-Thermus	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; DNA-templated transcription, elongation [GO:0006354]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of mRNA cleavage [GO:0031439]; regulation of DNA-templated transcription, elongation [GO:0032784]	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; regulation of DNA-templated transcription, elongation [GO:0032784]	DNA-templated transcription, elongation [GO:0006354]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of mRNA cleavage [GO:0031439]; regulation of DNA-templated transcription, elongation [GO:0032784]	regulation of DNA-templated transcription, elongation [GO:0032784]			DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]
d2p4ve1_d2euld1__1			Proteobacteria	Deinococcus-Thermus	DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]; DNA-templated transcription, elongation [GO:0006354]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of mRNA cleavage [GO:0031439]; regulation of DNA-templated transcription, elongation [GO:0032784]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA polymerase binding [GO:0070063]; regulation of DNA-templated transcription, elongation [GO:0032784]	DNA-templated transcription, elongation [GO:0006354]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of mRNA cleavage [GO:0031439]; regulation of DNA-templated transcription, elongation [GO:0032784]	regulation of DNA-templated transcription, elongation [GO:0032784]			DNA binding [GO:0003677]; RNA polymerase binding [GO:0070063]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA polymerase binding [GO:0070063]
d2p5bb__d5pm7a___1	Metazoa	Metazoa	Chordata	Chordata	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d2p5ea1_d3ma9l1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]			
d2p5ea2_d1aqdg2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]
d2p5eb2_d1a7ol___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2p5lc1_d1b4ab1__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2p5nb__d1afsb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid dehydrogenase activity [GO:0016229]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; hippocampus development [GO:0021766]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; hippocampus development [GO:0021766]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]	cytosol [GO:0005829]	17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid dehydrogenase activity [GO:0016229]
d2p5pa__d1urzb1__1					cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; peptidase activity [GO:0008233]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive regulation of viral genome replication [GO:0045070]; RNA 5'-cap (guanine-N7)-methylation [GO:0106005]; RNA stabilization [GO:0043489]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive regulation of viral genome replication [GO:0045070]; RNA 5'-cap (guanine-N7)-methylation [GO:0106005]; RNA stabilization [GO:0043489]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; peptidase activity [GO:0008233]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2p5pc__d2f08d___1		Metazoa		Arthropoda	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; peptidase activity [GO:0008233]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive regulation of viral genome replication [GO:0045070]; RNA 5'-cap (guanine-N7)-methylation [GO:0106005]; RNA stabilization [GO:0043489]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive regulation of viral genome replication [GO:0045070]; RNA 5'-cap (guanine-N7)-methylation [GO:0106005]; RNA stabilization [GO:0043489]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; peptidase activity [GO:0008233]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	
d2p5qb__d3m9jb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	glutathione peroxidase activity [GO:0004602]; metal ion binding [GO:0046872]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	response to oxidative stress [GO:0006979]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	glutathione peroxidase activity [GO:0004602]; metal ion binding [GO:0046872]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d2p5qd__d2c3qc1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	glutathione peroxidase activity [GO:0004602]; metal ion binding [GO:0046872]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	response to oxidative stress [GO:0006979]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione peroxidase activity [GO:0004602]; metal ion binding [GO:0046872]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]
d2p5ra__d1k3la2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	glutathione peroxidase activity [GO:0004602]; metal ion binding [GO:0046872]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	response to oxidative stress [GO:0006979]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione peroxidase activity [GO:0004602]; metal ion binding [GO:0046872]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2p5ud__d4z3ka___1		Metazoa	Deinococcus-Thermus	Chordata	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; aldo-keto reductase (NADP) activity [GO:0004033]; NADP binding [GO:0050661]; sepiapterin reductase activity [GO:0004757]; cofactor metabolic process [GO:0051186]; nitric oxide biosynthetic process [GO:0006809]; oxidation-reduction process [GO:0055114]; regulation of nitric-oxide synthase activity [GO:0050999]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cofactor metabolic process [GO:0051186]; nitric oxide biosynthetic process [GO:0006809]; oxidation-reduction process [GO:0055114]; regulation of nitric-oxide synthase activity [GO:0050999]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	aldo-keto reductase (NADP) activity [GO:0004033]; NADP binding [GO:0050661]; sepiapterin reductase activity [GO:0004757]
d2p5wa2_d1ffna2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2p5wb2_d1hyrc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; MHC class I protein binding [GO:0042288]; MHC class Ib receptor activity [GO:0032394]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; MHC class Ib receptor activity [GO:0032394]; MHC class I protein binding [GO:0042288]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]
d2p5wb2_d3wfhb1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2p5xa__d2dvoa___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; O-methyltransferase activity [GO:0008171]; nucleotide metabolic process [GO:0009117]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleotide metabolic process [GO:0009117]	nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	cytosol [GO:0005829]		NADH pyrophosphatase activity [GO:0035529]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; O-methyltransferase activity [GO:0008171]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]
d2p5ya__d3vdrb___1			Deinococcus-Thermus	Proteobacteria	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]					catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]
d2p6ba__d1t70a___1	Metazoa		Chordata	Deinococcus-Thermus	calcineurin complex [GO:0005955]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcolemma [GO:0042383]; Schaffer collateral - CA1 synapse [GO:0098685]; slit diaphragm [GO:0036057]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein phosphatase activity [GO:0033192]; cyclosporin A binding [GO:0016018]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; aging [GO:0007568]; brain development [GO:0007420]; calcineurin-mediated signaling [GO:0097720]; calcineurin-NFAT signaling cascade [GO:0033173]; calcium ion transport [GO:0006816]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; dephosphorylation [GO:0016311]; excitatory postsynaptic potential [GO:0060079]; Fc-epsilon receptor signaling pathway [GO:0038095]; G1/S transition of mitotic cell cycle [GO:0000082]; multicellular organismal response to stress [GO:0033555]; negative regulation of chromatin binding [GO:0035562]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of insulin secretion [GO:0046676]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of cardiac muscle hypertrophy in response to stress [GO:1903244]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of connective tissue replacement [GO:1905205]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endocytosis [GO:0045807]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein dephosphorylation [GO:0006470]; protein import into nucleus [GO:0006606]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue regeneration [GO:0043403]; T cell activation [GO:0042110]; transition between fast and slow fiber [GO:0014883]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]; phosphoenolpyruvate phosphatase activity [GO:0050189]	aging [GO:0007568]; brain development [GO:0007420]; calcineurin-mediated signaling [GO:0097720]; calcineurin-NFAT signaling cascade [GO:0033173]; calcium ion transport [GO:0006816]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; dephosphorylation [GO:0016311]; excitatory postsynaptic potential [GO:0060079]; Fc-epsilon receptor signaling pathway [GO:0038095]; G1/S transition of mitotic cell cycle [GO:0000082]; multicellular organismal response to stress [GO:0033555]; negative regulation of chromatin binding [GO:0035562]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of insulin secretion [GO:0046676]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of cardiac muscle hypertrophy in response to stress [GO:1903244]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of connective tissue replacement [GO:1905205]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endocytosis [GO:0045807]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein dephosphorylation [GO:0006470]; protein import into nucleus [GO:0006606]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue regeneration [GO:0043403]; T cell activation [GO:0042110]; transition between fast and slow fiber [GO:0014883]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcineurin complex [GO:0005955]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcolemma [GO:0042383]; Schaffer collateral - CA1 synapse [GO:0098685]; slit diaphragm [GO:0036057]; Z disc [GO:0030018]		calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein phosphatase activity [GO:0033192]; cyclosporin A binding [GO:0016018]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]; phosphoenolpyruvate phosphatase activity [GO:0050189]
d2p6bd1_d2pvba___1	Metazoa	Metazoa	Chordata	Chordata	calcineurin complex [GO:0005955]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcolemma [GO:0042383]; Schaffer collateral - CA1 synapse [GO:0098685]; slit diaphragm [GO:0036057]; Z disc [GO:0030018]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein phosphatase activity [GO:0033192]; cyclosporin A binding [GO:0016018]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; aging [GO:0007568]; brain development [GO:0007420]; calcineurin-mediated signaling [GO:0097720]; calcineurin-NFAT signaling cascade [GO:0033173]; calcium ion transport [GO:0006816]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; dephosphorylation [GO:0016311]; excitatory postsynaptic potential [GO:0060079]; Fc-epsilon receptor signaling pathway [GO:0038095]; G1/S transition of mitotic cell cycle [GO:0000082]; multicellular organismal response to stress [GO:0033555]; negative regulation of chromatin binding [GO:0035562]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of insulin secretion [GO:0046676]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of cardiac muscle hypertrophy in response to stress [GO:1903244]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of connective tissue replacement [GO:1905205]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endocytosis [GO:0045807]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein dephosphorylation [GO:0006470]; protein import into nucleus [GO:0006606]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue regeneration [GO:0043403]; T cell activation [GO:0042110]; transition between fast and slow fiber [GO:0014883]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]; calcium ion binding [GO:0005509]	aging [GO:0007568]; brain development [GO:0007420]; calcineurin-mediated signaling [GO:0097720]; calcineurin-NFAT signaling cascade [GO:0033173]; calcium ion transport [GO:0006816]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; dephosphorylation [GO:0016311]; excitatory postsynaptic potential [GO:0060079]; Fc-epsilon receptor signaling pathway [GO:0038095]; G1/S transition of mitotic cell cycle [GO:0000082]; multicellular organismal response to stress [GO:0033555]; negative regulation of chromatin binding [GO:0035562]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of insulin secretion [GO:0046676]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of cardiac muscle hypertrophy in response to stress [GO:1903244]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of connective tissue replacement [GO:1905205]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endocytosis [GO:0045807]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein dephosphorylation [GO:0006470]; protein import into nucleus [GO:0006606]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue regeneration [GO:0043403]; T cell activation [GO:0042110]; transition between fast and slow fiber [GO:0014883]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcineurin complex [GO:0005955]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcolemma [GO:0042383]; Schaffer collateral - CA1 synapse [GO:0098685]; slit diaphragm [GO:0036057]; Z disc [GO:0030018]	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]	calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein phosphatase activity [GO:0033192]; cyclosporin A binding [GO:0016018]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]	calcium ion binding [GO:0005509]
d2p6da__d2ejkb___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2p6hb__d2cu5b___1			Crenarchaeota	Deinococcus-Thermus								
d2p6ma__d1c7zb___1		Metazoa	Deinococcus-Thermus	Chordata	catalytic activity [GO:0003824]	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; animal organ regeneration [GO:0031100]; carbohydrate phosphorylation [GO:0046835]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; positive regulation of glucokinase activity [GO:0033133]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]		animal organ regeneration [GO:0031100]; carbohydrate phosphorylation [GO:0046835]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; positive regulation of glucokinase activity [GO:0033133]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]		6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]	catalytic activity [GO:0003824]	6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]
d2p6ma__d1t8pb___1		Metazoa	Deinococcus-Thermus	Chordata	catalytic activity [GO:0003824]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	catalytic activity [GO:0003824]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]
d2p6mb__d4odib___1			Deinococcus-Thermus	Apicomplexa	catalytic activity [GO:0003824]	phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]			catalytic activity [GO:0003824]	phosphoglycerate mutase activity [GO:0004619]
d2p6oa__d2pa0a___1			Deinococcus-Thermus	Deinococcus-Thermus	catalytic activity [GO:0003824]	catalytic activity [GO:0003824]					catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d2p6ob__d4ij5b___1			Deinococcus-Thermus	Aquificae	catalytic activity [GO:0003824]	phosphoserine phosphatase activity [GO:0004647]; L-serine biosynthetic process [GO:0006564]		L-serine biosynthetic process [GO:0006564]			catalytic activity [GO:0003824]	phosphoserine phosphatase activity [GO:0004647]
d2p6pa1_d3otia1__1			Actinobacteria	Actinobacteria	transferase activity [GO:0016740]	glucosyltransferase activity [GO:0046527]					transferase activity [GO:0016740]	glucosyltransferase activity [GO:0046527]
d2p6ra1_d1oyya1__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA repair [GO:0006281]	bacterial nucleoid [GO:0043590]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; replisome [GO:0030894]; single-stranded DNA-dependent ATP-dependent DNA helicase complex [GO:0017117]; 3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA-dependent ATPase activity [GO:0008094]; four-way junction helicase activity [GO:0009378]; single-stranded DNA helicase activity [GO:0017116]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432]	DNA repair [GO:0006281]	cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432]		bacterial nucleoid [GO:0043590]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; replisome [GO:0030894]; single-stranded DNA-dependent ATP-dependent DNA helicase complex [GO:0017117]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]	3'-5' DNA helicase activity [GO:0043138]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA helicase activity [GO:0003678]; four-way junction helicase activity [GO:0009378]; single-stranded DNA helicase activity [GO:0017116]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2p6ra2_d3kx2b4__1		Fungi	Euryarchaeota	Ascomycota	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA repair [GO:0006281]	90S preribosome [GO:0030686]; mitochondrion [GO:0005739]; post-mRNA release spliceosomal complex [GO:0071014]; ATP binding [GO:0005524]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; maturation of SSU-rRNA [GO:0030490]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; spliceosomal complex disassembly [GO:0000390]	DNA repair [GO:0006281]	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; maturation of SSU-rRNA [GO:0030490]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; spliceosomal complex disassembly [GO:0000390]		90S preribosome [GO:0030686]; mitochondrion [GO:0005739]; post-mRNA release spliceosomal complex [GO:0071014]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]	ATP binding [GO:0005524]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]
d2p6xb__d2veva___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; kinase binding [GO:0019900]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase binding [GO:0031625]; autophagy [GO:0006914]; cellular response to muramyl dipeptide [GO:0071225]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; phosphoanandamide dephosphorylation [GO:0035644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of toll-like receptor 3 signaling pathway [GO:0034141]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of type I interferon production [GO:0032481]; protein dephosphorylation [GO:0006470]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of innate immune response [GO:0045088]; regulation of natural killer cell proliferation [GO:0032817]; regulation of NIK/NF-kappaB signaling [GO:1901222]; response to lipopolysaccharide [GO:0032496]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	autophagy [GO:0006914]; cellular response to muramyl dipeptide [GO:0071225]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; phosphoanandamide dephosphorylation [GO:0035644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of toll-like receptor 3 signaling pathway [GO:0034141]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of type I interferon production [GO:0032481]; protein dephosphorylation [GO:0006470]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of innate immune response [GO:0045088]; regulation of natural killer cell proliferation [GO:0032817]; regulation of NIK/NF-kappaB signaling [GO:1901222]; response to lipopolysaccharide [GO:0032496]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	kinase binding [GO:0019900]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase binding [GO:0031625]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2p6xb__d3s3fa1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; kinase binding [GO:0019900]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase binding [GO:0031625]; autophagy [GO:0006914]; cellular response to muramyl dipeptide [GO:0071225]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; phosphoanandamide dephosphorylation [GO:0035644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of toll-like receptor 3 signaling pathway [GO:0034141]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of type I interferon production [GO:0032481]; protein dephosphorylation [GO:0006470]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of innate immune response [GO:0045088]; regulation of natural killer cell proliferation [GO:0032817]; regulation of NIK/NF-kappaB signaling [GO:1901222]; response to lipopolysaccharide [GO:0032496]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]	apical part of cell [GO:0045177]; axon [GO:0030424]; integral component of membrane [GO:0016021]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axon guidance [GO:0007411]; branching involved in open tracheal system development [GO:0060446]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470]	autophagy [GO:0006914]; cellular response to muramyl dipeptide [GO:0071225]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; phosphoanandamide dephosphorylation [GO:0035644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of toll-like receptor 3 signaling pathway [GO:0034141]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of type I interferon production [GO:0032481]; protein dephosphorylation [GO:0006470]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of innate immune response [GO:0045088]; regulation of natural killer cell proliferation [GO:0032817]; regulation of NIK/NF-kappaB signaling [GO:1901222]; response to lipopolysaccharide [GO:0032496]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]	axon guidance [GO:0007411]; branching involved in open tracheal system development [GO:0060446]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	apical part of cell [GO:0045177]; axon [GO:0030424]; integral component of membrane [GO:0016021]	kinase binding [GO:0019900]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase binding [GO:0031625]	protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d2p71a__d3q8ia___1	Metazoa	Metazoa	Arthropoda	Arthropoda	pheromone binding [GO:0005550]; response to pheromone [GO:0019236]	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]	response to pheromone [GO:0019236]	olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]	pheromone binding [GO:0005550]	dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]
d2p76h1_d6ptda___1			Firmicutes	Firmicutes	phosphoric diester hydrolase activity [GO:0008081]; lipid metabolic process [GO:0006629]	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	lipid metabolic process [GO:0006629]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	phosphoric diester hydrolase activity [GO:0008081]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]
d2p78b__d2bifb2__1		Metazoa	Deinococcus-Thermus	Chordata	catalytic activity [GO:0003824]	cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]		fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]		cytosol [GO:0005829]	catalytic activity [GO:0003824]	6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]
d2p78b__d3nfyb___1		Metazoa	Deinococcus-Thermus	Chordata	catalytic activity [GO:0003824]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	catalytic activity [GO:0003824]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]
d2p7le__d2p7pa___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2p7me__d2c21d___1			Firmicutes		cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; response to antibiotic [GO:0046677]	lactoylglutathione lyase activity [GO:0004462]; metal ion binding [GO:0046872]	response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]		metal ion binding [GO:0046872]	lactoylglutathione lyase activity [GO:0004462]; metal ion binding [GO:0046872]
d2p7pc__d4opna___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; regulation of transcription by RNA polymerase II [GO:0006357]	response to antibiotic [GO:0046677]	carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]
d2p7qa__d5cj3b___1				Actinobacteria		drug binding [GO:0008144]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]				drug binding [GO:0008144]
d2p7sa__d11bga___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]		RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d2p7ta1_d3u46l2__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2p7tb2_d5jhll1__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	voltage-gated potassium channel complex [GO:0008076]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2p80a1_d5ue6f2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2p80b1_d3h4fa1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2p80c2_d3od3a3__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d2p80d__d2bw5a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2p85a__d2ij5d___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]
d2p85d__d2uwhe___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d2p85f__d1f4ua___1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]
d2p88c2_d2dw7d1__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]; peptide metabolic process [GO:0006518]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	peptide metabolic process [GO:0006518]	protein homooligomerization [GO:0051260]			magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]
d2p88d2_d1ecqd1__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]; peptide metabolic process [GO:0006518]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	peptide metabolic process [GO:0006518]	D-glucarate catabolic process [GO:0042838]			magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d2p88e1_d1p48b2__1		Fungi	Firmicutes	Ascomycota	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]; peptide metabolic process [GO:0006518]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	peptide metabolic process [GO:0006518]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2p88e1_d3p93g1__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]; peptide metabolic process [GO:0006518]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	peptide metabolic process [GO:0006518]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d2p88f2_d3uxkd2__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]; peptide metabolic process [GO:0006518]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	peptide metabolic process [GO:0006518]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d2p88h1_d1ec9a2__1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]; peptide metabolic process [GO:0006518]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	peptide metabolic process [GO:0006518]	D-glucarate catabolic process [GO:0042838]			magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d2p8ba2_d1p48a1__1		Fungi	Firmicutes	Ascomycota	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]; peptide metabolic process [GO:0006518]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	peptide metabolic process [GO:0006518]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2p8pb1_d1dbjl1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2p8va__d1mixa2__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; G protein-coupled glutamate receptor binding [GO:0035256]; identical protein binding [GO:0042802]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of interleukin-2 production [GO:0032703]; protein targeting [GO:0006605]; regulation of store-operated calcium entry [GO:2001256]	actin cortical patch [GO:0030479]; cell [GO:0005623]; cell surface [GO:0009986]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; clathrin light chain binding [GO:0032051]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; structural constituent of cytoskeleton [GO:0005200]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; clathrin coat assembly [GO:0048268]; cytoskeletal anchoring at plasma membrane [GO:0007016]; endocytosis [GO:0006897]; positive regulation of receptor-mediated endocytosis [GO:0048260]	G protein-coupled glutamate receptor signaling pathway [GO:0007216]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of interleukin-2 production [GO:0032703]; protein targeting [GO:0006605]; regulation of store-operated calcium entry [GO:2001256]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; clathrin coat assembly [GO:0048268]; cytoskeletal anchoring at plasma membrane [GO:0007016]; endocytosis [GO:0006897]; positive regulation of receptor-mediated endocytosis [GO:0048260]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]	actin cortical patch [GO:0030479]; cell [GO:0005623]; cell surface [GO:0009986]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	G protein-coupled glutamate receptor binding [GO:0035256]; identical protein binding [GO:0042802]	actin filament binding [GO:0051015]; clathrin adaptor activity [GO:0035615]; clathrin binding [GO:0030276]; clathrin light chain binding [GO:0032051]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol binding [GO:0035091]; structural constituent of cytoskeleton [GO:0005200]
d2p93a__d2f91a1__1	Metazoa	Metazoa	Chordata	Arthropoda	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2p99a__d3tb5b___1			Proteobacteria		cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]		protein initiator methionine removal [GO:0070084]		cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]	
d2p9ca1_d5ldha1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	L-serine biosynthetic process [GO:0006564]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]	L-lactate dehydrogenase activity [GO:0004459]
d2p9cb3_d1psda3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	L-serine biosynthetic process [GO:0006564]	L-serine biosynthetic process [GO:0006564]	cytosol [GO:0005829]	cytosol [GO:0005829]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]
d2p9cb3_d3c1nd3__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	cytosol [GO:0005829]; aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]; homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	L-serine biosynthetic process [GO:0006564]	homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	cytosol [GO:0005829]	cytosol [GO:0005829]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]	aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]
d2p9fa__d4ij5a___1			Deinococcus-Thermus	Aquificae	catalytic activity [GO:0003824]	phosphoserine phosphatase activity [GO:0004647]; L-serine biosynthetic process [GO:0006564]		L-serine biosynthetic process [GO:0006564]			catalytic activity [GO:0003824]	phosphoserine phosphatase activity [GO:0004647]
d2p9fa__d4pgmc___1		Fungi	Deinococcus-Thermus	Ascomycota	catalytic activity [GO:0003824]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]	phosphoglycerate mutase activity [GO:0004619]
d2p9gb1_d2naca1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	cytoplasm [GO:0005737]; formate dehydrogenase (NAD+) activity [GO:0008863]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; formate catabolic process [GO:0042183]	L-serine biosynthetic process [GO:0006564]	formate catabolic process [GO:0042183]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]	formate dehydrogenase (NAD+) activity [GO:0008863]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d2p9hb__d1sxga___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]	regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]		bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]
d2p9ld1_d2p9pf___1	Metazoa	Metazoa	Chordata	Chordata	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	actin filament binding [GO:0051015]	actin filament binding [GO:0051015]
d2p9ra__d2a73b1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]; calcium-dependent protein binding [GO:0048306]; endopeptidase inhibitor activity [GO:0004866]; enzyme binding [GO:0019899]; growth factor binding [GO:0019838]; interleukin-1 binding [GO:0019966]; interleukin-8 binding [GO:0019959]; protease binding [GO:0002020]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor binding [GO:0005102]; tumor necrosis factor binding [GO:0043120]; blood coagulation, intrinsic pathway [GO:0007597]; extracellular matrix disassembly [GO:0022617]; negative regulation of complement activation, lectin pathway [GO:0001869]; platelet degranulation [GO:0002576]; regulation of small GTPase mediated signal transduction [GO:0051056]; stem cell differentiation [GO:0048863]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	blood coagulation, intrinsic pathway [GO:0007597]; extracellular matrix disassembly [GO:0022617]; negative regulation of complement activation, lectin pathway [GO:0001869]; platelet degranulation [GO:0002576]; regulation of small GTPase mediated signal transduction [GO:0051056]; stem cell differentiation [GO:0048863]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	calcium-dependent protein binding [GO:0048306]; endopeptidase inhibitor activity [GO:0004866]; enzyme binding [GO:0019899]; growth factor binding [GO:0019838]; interleukin-1 binding [GO:0019966]; interleukin-8 binding [GO:0019959]; protease binding [GO:0002020]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor binding [GO:0005102]; tumor necrosis factor binding [GO:0043120]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d2p9sb__d3idha1__1	Metazoa	Metazoa	Chordata	Chordata	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	actin filament binding [GO:0051015]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]
d2p9ta__d5bt8c1__1	Metazoa		Chordata	Proteobacteria	cilium [GO:0005929]; cytosol [GO:0005829]; sperm fibrous sheath [GO:0035686]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; flagellated sperm motility [GO:0030317]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; phosphorylation [GO:0016310]; positive regulation of oxidative phosphorylation [GO:1903862]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; glycolytic process [GO:0006096]	flagellated sperm motility [GO:0030317]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; phosphorylation [GO:0016310]; positive regulation of oxidative phosphorylation [GO:1903862]	glycolytic process [GO:0006096]	cilium [GO:0005929]; cytosol [GO:0005829]; sperm fibrous sheath [GO:0035686]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]	ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]
d2p9ud1_d2p9kf___1	Metazoa	Metazoa	Chordata	Chordata	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	actin filament binding [GO:0051015]	actin filament binding [GO:0051015]
d2p9yb__d2owda___1			Deinococcus-Thermus	Deinococcus-Thermus	catalytic activity [GO:0003824]	catalytic activity [GO:0003824]					catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d2p9za__d3kkka___1			Deinococcus-Thermus	Apicomplexa	catalytic activity [GO:0003824]	cytosol [GO:0005829]; phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytosol [GO:0005829]	catalytic activity [GO:0003824]	phosphoglycerate mutase activity [GO:0004619]
d2pa0b__d1skba___1		Fungi	Deinococcus-Thermus	Ascomycota	catalytic activity [GO:0003824]	extracellular region [GO:0005576]; 3-phytase activity [GO:0016158]; acid phosphatase activity [GO:0003993]				extracellular region [GO:0005576]	catalytic activity [GO:0003824]	3-phytase activity [GO:0016158]; acid phosphatase activity [GO:0003993]
d2pa1a1_d5e11a1__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell adherens junction [GO:0005913]; filamentous actin [GO:0031941]; nucleus [GO:0005634]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; actin cytoskeleton organization [GO:0030036]; heart development [GO:0007507]; muscle structure development [GO:0061061]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]	actin cytoskeleton organization [GO:0030036]; heart development [GO:0007507]; muscle structure development [GO:0061061]		cell-cell adherens junction [GO:0005913]; filamentous actin [GO:0031941]; nucleus [GO:0005634]; stress fiber [GO:0001725]; Z disc [GO:0030018]		actin binding [GO:0003779]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]
d2pa3a1_d4okna1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	L-serine biosynthetic process [GO:0006564]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2paba__d3cn3a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d2paea1_d4ubha___1		Metazoa	Firmicutes	Chordata	isomerase activity [GO:0016853]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]		cysteine metabolic process [GO:0006534]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]		cytosol [GO:0005829]	isomerase activity [GO:0016853]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d2paeb__d2b9uk___1			Firmicutes	Crenarchaeota	isomerase activity [GO:0016853]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]		dTDP-rhamnose biosynthetic process [GO:0019305]			isomerase activity [GO:0016853]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d2pakb__d2pama1__1			Firmicutes	Firmicutes	isomerase activity [GO:0016853]	isomerase activity [GO:0016853]					isomerase activity [GO:0016853]	isomerase activity [GO:0016853]
d2pala__d2znda___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]; calcium ion binding [GO:0005509]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]
d2pawa1_d3gjwa1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA binding [GO:0003677]; NAD binding [GO:0051287]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]; ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2pawa2_d4r6ed2__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA binding [GO:0003677]; NAD binding [GO:0051287]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]; ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2pbcb1_d4dz2b1__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	metal ion binding [GO:0046872]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]			endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]		FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	metal ion binding [GO:0046872]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2pbcc1_d5hwca1__1	Metazoa	Fungi	Chordata	Ascomycota	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]		chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2pbga__d3pzua___1			Firmicutes	Firmicutes	6-phospho-beta-galactosidase activity [GO:0033920]; lactose catabolic process via tagatose-6-phosphate [GO:0019512]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	lactose catabolic process via tagatose-6-phosphate [GO:0019512]	cellulose catabolic process [GO:0030245]			6-phospho-beta-galactosidase activity [GO:0033920]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d2pbha__d5tl7b2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2pbjb2_d4pgtb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2pbjc2_d2vm1a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]	cell [GO:0005623]	electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]	protein disulfide oxidoreductase activity [GO:0015035]
d2pbjd2_d1f2ea2__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]		cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]		electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione transferase activity [GO:0004364]
d2pboa__d1v0na___1	Fungi		Ascomycota	Actinobacteria	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]; cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	xylan catabolic process [GO:0045493]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d2pbpa__d1tyfk___1			Firmicutes	Proteobacteria	catalytic activity [GO:0003824]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	catalytic activity [GO:0003824]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2pbqc__d5erua2__1		Metazoa	Aquificae	Chordata	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]		cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]
d2pbra__d1efca3__1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2pbrb__d2zsaa___1			Aquificae	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d2pbwa1_d2g29a___1	Metazoa		Chordata	Cyanobacteria	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	plasma membrane [GO:0005886]; ion transport [GO:0006811]; nitrate assimilation [GO:0042128]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	ion transport [GO:0006811]; nitrate assimilation [GO:0042128]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	plasma membrane [GO:0005886]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	
d2pc5a__d5h4ja___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]; dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d2pc8a__d4w8la___1	Fungi		Ascomycota	Firmicutes	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]; cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	xylan catabolic process [GO:0045493]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]		cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d2pcbb__d1gjqa1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	periplasmic space [GO:0042597]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d2pcca__d5sw6b2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2pccb__d1m6za2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	periplasmic space [GO:0042597]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2pccd__d1cnoh___1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	periplasmic space [GO:0042597]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2pceb1_d1sjdb2__1			Proteobacteria	Actinobacteria	metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]		menaquinone biosynthetic process [GO:0009234]			metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d2pcec2_d5bofa2__1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]		glycolytic process [GO:0006096]; pathogenesis [GO:0009405]		cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2pced2_d5eu9h2__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2pcee2_d3qn3c2__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2pcee2_d3twad2__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]		carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			metal ion binding [GO:0046872]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]
d2pcef1_d1pdya2__1		Metazoa	Proteobacteria	Arthropoda	metal ion binding [GO:0046872]	phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		phosphopyruvate hydratase complex [GO:0000015]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2pceg1_d4za0b1__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2pceg2_d1nela1__1		Fungi	Proteobacteria	Ascomycota	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2pceh1_d1sjbd2__1			Proteobacteria	Actinobacteria	metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]		menaquinone biosynthetic process [GO:0009234]			metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d2pckb__d2eh5a___1			Euryarchaeota	Euryarchaeota	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	diphthine synthase activity [GO:0004164]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]			diphthine synthase activity [GO:0004164]	diphthine synthase activity [GO:0004164]
d2pcpa1_d5obfl2__1												
d2pcpb1_d2clzb___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2pcpc2_d4u0qb1__1				Apicomplexa								
d2pcsa1_d3tvqa___1			Firmicutes	Actinobacteria		O-methyltransferase activity [GO:0008171]; antibiotic biosynthetic process [GO:0017000]		antibiotic biosynthetic process [GO:0017000]				O-methyltransferase activity [GO:0008171]
d2pcua1_d5jc6a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; histone acetylation [GO:0016573]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	histone acetylation [GO:0016573]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2pcxa1_d2j6wb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2pcxa1_d3kmdb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d2pd2b__d2d1pb1__1			Crenarchaeota	Proteobacteria		cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]; sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]; tRNA wobble position uridine thiolation [GO:0002143]		tRNA wobble position uridine thiolation [GO:0002143]		cytosol [GO:0005829]; sulfurtransferase complex [GO:1990228]		sulfur carrier activity [GO:0097163]; sulfurtransferase activity [GO:0016783]
d2pd3a__d1pjqa1__1			Proteobacteria	Proteobacteria	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	NAD binding [GO:0051287]; precorrin-2 dehydrogenase activity [GO:0043115]; sirohydrochlorin ferrochelatase activity [GO:0051266]; uroporphyrin-III C-methyltransferase activity [GO:0004851]; cobalamin biosynthetic process [GO:0009236]; siroheme biosynthetic process [GO:0019354]	fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	cobalamin biosynthetic process [GO:0009236]; siroheme biosynthetic process [GO:0019354]			enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]	NAD binding [GO:0051287]; precorrin-2 dehydrogenase activity [GO:0043115]; sirohydrochlorin ferrochelatase activity [GO:0051266]; uroporphyrin-III C-methyltransferase activity [GO:0004851]
d2pd3b__d1lnqg3__1			Proteobacteria	Euryarchaeota	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	potassium ion transport [GO:0006813]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2pd4b__d2czzx___1			Proteobacteria		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]		fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]				enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]	
d2pd4c__d3pk0a1__1			Proteobacteria	Actinobacteria	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	metal ion binding [GO:0046872]	fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]				enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]	metal ion binding [GO:0046872]
d2pd4d__d1agna2__1		Metazoa	Proteobacteria	Chordata	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; oxidation-reduction process [GO:0055114]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; plasma membrane [GO:0005886]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; aldehyde oxidase activity [GO:0004031]; ethanol binding [GO:0035276]; omega-hydroxydecanoate dehydrogenase activity [GO:0050153]; receptor antagonist activity [GO:0048019]; retinol binding [GO:0019841]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d2pd9a__d1zsxa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	axon terminus [GO:0043679]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; pinceau fiber [GO:1990031]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; voltage-gated potassium channel complex [GO:0008076]; aldo-keto reductase (NADP) activity [GO:0004033]; potassium channel regulator activity [GO:0015459]; voltage-gated potassium channel activity [GO:0005249]; hematopoietic progenitor cell differentiation [GO:0002244]; NADPH oxidation [GO:0070995]; neuromuscular process [GO:0050905]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	hematopoietic progenitor cell differentiation [GO:0002244]; NADPH oxidation [GO:0070995]; neuromuscular process [GO:0050905]; neutrophil degranulation [GO:0043312]; oxidation-reduction process [GO:0055114]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	axon terminus [GO:0043679]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; pinceau fiber [GO:1990031]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; voltage-gated potassium channel complex [GO:0008076]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	aldo-keto reductase (NADP) activity [GO:0004033]; potassium channel regulator activity [GO:0015459]; voltage-gated potassium channel activity [GO:0005249]
d2pdaa3_d1umdb2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	electron transport chain [GO:0022900]		cytoplasm [GO:0005737]		4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]
d2pdab3_d5nd6b3__1		Viridiplantae	Proteobacteria	Chlorophyta	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	cytosol [GO:0005829]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	electron transport chain [GO:0022900]	pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	transketolase activity [GO:0004802]
d2pdja__d3d3fa___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	methylglyoxal reductase (NADPH-dependent) activity [GO:0043892]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	methylglyoxal reductase (NADPH-dependent) activity [GO:0043892]
d2pdpa__d3wbwb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2pdqa__d2hvoa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d2pdwa__d3cavb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytosol [GO:0005829]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]
d2pdxa__d3h7ua___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	chloroplast [GO:0009507]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; steroid dehydrogenase activity [GO:0016229]; oxidation-reduction process [GO:0055114]; response to cold [GO:0009409]; response to salt stress [GO:0009651]; response to toxic substance [GO:0009636]; response to water deprivation [GO:0009414]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	oxidation-reduction process [GO:0055114]; response to cold [GO:0009409]; response to salt stress [GO:0009651]; response to toxic substance [GO:0009636]; response to water deprivation [GO:0009414]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	chloroplast [GO:0009507]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; steroid dehydrogenase activity [GO:0016229]
d2pdya__d4ijcb___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; D-arabinose 1-dehydrogenase [NAD(P)+] activity [GO:0045290]; oxidoreductase activity [GO:0016491]; cellular carbohydrate metabolic process [GO:0044262]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cellular carbohydrate metabolic process [GO:0044262]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytosol [GO:0005829]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; D-arabinose 1-dehydrogenase [NAD(P)+] activity [GO:0045290]; oxidoreductase activity [GO:0016491]
d2pe5b2_d3tb6b___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	negative regulation of transcription, DNA-templated [GO:0045892]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2peca__d2iq7b___1		Fungi	Proteobacteria	Ascomycota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]; polygalacturonase activity [GO:0004650]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]	polygalacturonase activity [GO:0004650]
d2pejb1_d2pena___1			Cyanobacteria	Cyanobacteria	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2pejd1_d2py8d___1			Cyanobacteria	Cyanobacteria	metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d2pejf1_d2pemb1__1			Cyanobacteria	Cyanobacteria	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2pejf1_d5bs2a___1		Viridiplantae	Cyanobacteria	Chlorophyta	metal ion binding [GO:0046872]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2peka1_d2peqb___1			Cyanobacteria	Cyanobacteria	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2pelc__d2zmkb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d2peld__d4gkxe___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; sarcomere [GO:0030017]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; blood coagulation [GO:0007596]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; negative regulation of protein targeting to mitochondrion [GO:1903215]; positive regulation of organelle organization [GO:0010638]; protein folding [GO:0006457]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]		blood coagulation [GO:0007596]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; negative regulation of protein targeting to mitochondrion [GO:1903215]; positive regulation of organelle organization [GO:0010638]; protein folding [GO:0006457]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]		collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; sarcomere [GO:0030017]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d2peme1_d3q20a___1			Cyanobacteria	Cyanobacteria	metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d2penc__d3hybb1__1			Cyanobacteria	Cyanobacteria	metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d2peqb__d4gr6a___1		Viridiplantae	Cyanobacteria	Streptophyta	metal ion binding [GO:0046872]	chloroplast stroma [GO:0009570]; protein folding chaperone [GO:0044183]; chaperone-mediated protein folding [GO:0061077]		chaperone-mediated protein folding [GO:0061077]		chloroplast stroma [GO:0009570]	metal ion binding [GO:0046872]	protein folding chaperone [GO:0044183]
d2pesa1_d3f2ma2__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d2pesa2_d1a8rj___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d2peva__d2c91i___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; phenanthrene-9,10-epoxide hydrolase activity [GO:0019119]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; phenanthrene-9,10-epoxide hydrolase activity [GO:0019119]
d2pf4a__d6enca3__1	Metazoa	Metazoa	Chordata	Chordata	chromosome, centromeric region [GO:0000775]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; lateral plasma membrane [GO:0016328]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; synapse [GO:0045202]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; protein phosphatase regulator activity [GO:0019888]; protein serine/threonine phosphatase activity [GO:0004722]; chromosome segregation [GO:0007059]; female meiotic nuclear division [GO:0007143]; meiotic sister chromatid cohesion, centromeric [GO:0051754]; meiotic spindle elongation [GO:0051232]; mitotic sister chromatid separation [GO:0051306]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein-containing complex assembly [GO:0065003]; regulation of meiotic cell cycle process involved in oocyte maturation [GO:1903538]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	chromosome segregation [GO:0007059]; female meiotic nuclear division [GO:0007143]; meiotic sister chromatid cohesion, centromeric [GO:0051754]; meiotic spindle elongation [GO:0051232]; mitotic sister chromatid separation [GO:0051306]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein-containing complex assembly [GO:0065003]; regulation of meiotic cell cycle process involved in oocyte maturation [GO:1903538]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	chromosome, centromeric region [GO:0000775]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; lateral plasma membrane [GO:0016328]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; synapse [GO:0045202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; protein phosphatase regulator activity [GO:0019888]; protein serine/threonine phosphatase activity [GO:0004722]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2pfea__d4ghta1__1			Actinobacteria		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2pfkb__d1mtob___1			Proteobacteria	Firmicutes	6-phosphofructokinase complex [GO:0005945]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; 6-phosphofructokinase activity [GO:0003872]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; fructose-6-phosphate binding [GO:0070095]; GDP binding [GO:0019003]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; monosaccharide binding [GO:0048029]; ribonucleotide binding [GO:0032553]; canonical glycolysis [GO:0061621]; cellular carbohydrate catabolic process [GO:0044275]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose 6-phosphate metabolic process [GO:0006002]; glucose catabolic process [GO:0006007]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]; 6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; fructose 6-phosphate metabolic process [GO:0006002]	canonical glycolysis [GO:0061621]; cellular carbohydrate catabolic process [GO:0044275]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose 6-phosphate metabolic process [GO:0006002]; glucose catabolic process [GO:0006007]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]	fructose 6-phosphate metabolic process [GO:0006002]	6-phosphofructokinase complex [GO:0005945]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	6-phosphofructokinase activity [GO:0003872]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; fructose-6-phosphate binding [GO:0070095]; GDP binding [GO:0019003]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; monosaccharide binding [GO:0048029]; ribonucleotide binding [GO:0032553]	6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d2pflb__d5r1ra2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; formate C-acetyltransferase activity [GO:0008861]; glucose metabolic process [GO:0006006]; threonine catabolic process [GO:0006567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	glucose metabolic process [GO:0006006]; threonine catabolic process [GO:0006567]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	formate C-acetyltransferase activity [GO:0008861]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2pfmb__d3r6vg___1			Firmicutes	Firmicutes	(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity [GO:0070626]; N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity [GO:0004018]; 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]; aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]	aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]			(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity [GO:0070626]; N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity [GO:0004018]	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]
d2pfoa1_d1bnpa___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d2pg0a2_d1egea1__1		Metazoa	Firmicutes	Chordata	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]		carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]		axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]
d2pg5b1_d1phca___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2pg5c__d3t3sf___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d2pg6a__d1geda___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]		arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2pg6b1_d3cbdb___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d2pg7c__d5it1a___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]		arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2pg7d__d2zwua___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2pg9a1_d1y60c___1				Proteobacteria		cytoplasm [GO:0005737]; carbon-nitrogen lyase activity [GO:0016840]; carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]		carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]		cytoplasm [GO:0005737]		carbon-nitrogen lyase activity [GO:0016840]
d2pgha__d2r1hc___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2pgta1_d5ecpe2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2pgtb1_d5lola2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; glutathione binding [GO:0043295]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; positive regulation of salicylic acid mediated signaling pathway [GO:0080151]; protein glutathionylation [GO:0010731]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	positive regulation of salicylic acid mediated signaling pathway [GO:0080151]; protein glutathionylation [GO:0010731]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione binding [GO:0043295]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]
d2pgtb2_d1gsya2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]
d2pgtb2_d2hzfa1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	virion [GO:0019012]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	virion [GO:0019012]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d2ph9c1_d4afha___1	Metazoa	Metazoa	Mollusca	Annelida	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]
d2phaa__d4qa1d1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]
d2phba__d3f9fb___1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2phdd__d3bu7a1__1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	gentisate 1,2-dioxygenase activity [GO:0047922]; metal ion binding [GO:0046872]; cellular aromatic compound metabolic process [GO:0006725]		cellular aromatic compound metabolic process [GO:0006725]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	gentisate 1,2-dioxygenase activity [GO:0047922]; metal ion binding [GO:0046872]
d2phfa__d1faya___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2phfb__d2dvda___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2phga1_d1vola1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d2phha2_d1doba2__1			Proteobacteria	Proteobacteria	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	benzoate catabolic process via hydroxylation [GO:0043640]	benzoate catabolic process via hydroxylation [GO:0043640]			4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d2phib__d1tjka___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]; bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d2phlc1_d1dgr.4__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	aleurone grain [GO:0033095]; vacuole [GO:0005773]; nutrient reservoir activity [GO:0045735]	protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]; protein homotrimerization [GO:0070207]		protein homotrimerization [GO:0070207]	aleurone grain [GO:0033095]; vacuole [GO:0005773]	protein-containing complex [GO:0032991]	nutrient reservoir activity [GO:0045735]	identical protein binding [GO:0042802]; nutrient reservoir activity [GO:0045735]
d2phta__d5duud___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]		cell adhesion [GO:0007155]		collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2phtb__d1avbb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; nutrient reservoir activity [GO:0045735]; toxin activity [GO:0090729]; defense response [GO:0006952]		defense response [GO:0006952]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; nutrient reservoir activity [GO:0045735]; toxin activity [GO:0090729]
d2phub__d2e51a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d2phwb__d2fnja1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	elongin complex [GO:0070449]; VCB complex [GO:0030891]; protein-containing complex binding [GO:0044877]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]		positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]		elongin complex [GO:0070449]; VCB complex [GO:0030891]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	protein-containing complex binding [GO:0044877]
d2pi0b__d2irfj___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cell population proliferation [GO:0008283]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cell population proliferation [GO:0008283]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d2pi0c__d2irfh___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cell population proliferation [GO:0008283]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cell population proliferation [GO:0008283]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d2pi2h__d5e7na1__1	Metazoa	Metazoa	Chordata	Chordata	DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; single-stranded DNA binding [GO:0003697]; base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]; damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]	damaged DNA binding [GO:0003684]; single-stranded DNA binding [GO:0003697]	damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]
d2piaa1_d1i8da1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; riboflavin synthase activity [GO:0004746]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]		cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	riboflavin synthase activity [GO:0004746]
d2piea2_d3gqsb___1	Metazoa		Chordata	Chlamydiae	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; ubiquitin ligase complex [GO:0000151]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone exchange [GO:0043486]; histone H2A K63-linked ubiquitination [GO:0070535]; histone H2A ubiquitination [GO:0033522]; histone H2B ubiquitination [GO:0033523]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; ubiquitin-dependent protein catabolic process [GO:0006511]	integral component of membrane [GO:0016021]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone exchange [GO:0043486]; histone H2A K63-linked ubiquitination [GO:0070535]; histone H2A ubiquitination [GO:0033522]; histone H2B ubiquitination [GO:0033523]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; ubiquitin-dependent protein catabolic process [GO:0006511]		chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; ubiquitin ligase complex [GO:0000151]	integral component of membrane [GO:0016021]	chromatin binding [GO:0003682]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	
d2piia__d1v6hb___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; small molecule binding [GO:0036094]; regulation of catalytic activity [GO:0050790]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of nitrogen utilization [GO:0006808]	cytoplasm [GO:0005737]; response to metal ion [GO:0010038]	regulation of catalytic activity [GO:0050790]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of nitrogen utilization [GO:0006808]	response to metal ion [GO:0010038]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; small molecule binding [GO:0036094]	
d2piya__d2o4hb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	cytosol [GO:0005829]; nucleus [GO:0005634]; aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	proteolysis [GO:0006508]	aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	extracellular space [GO:0005615]	cytosol [GO:0005829]; nucleus [GO:0005634]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2pj0a__d1gytb2__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	proteolysis [GO:0006508]	peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	extracellular space [GO:0005615]	cytoplasm [GO:0005737]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]
d2pj1a__d1ellp___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2pj1c__d2anpa1__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	proteolysis [GO:0006508]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]
d2pj2c__d3lmsa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; blood coagulation [GO:0007596]; cellular response to glucose stimulus [GO:0071333]; fibrinolysis [GO:0042730]; liver regeneration [GO:0097421]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of plasminogen activation [GO:0010757]; positive regulation of extracellular matrix constituent secretion [GO:0003331]; proteolysis [GO:0006508]; regulation of complement activation [GO:0030449]; response to drug [GO:0042493]; response to heat [GO:0009408]	proteolysis [GO:0006508]	blood coagulation [GO:0007596]; cellular response to glucose stimulus [GO:0071333]; fibrinolysis [GO:0042730]; liver regeneration [GO:0097421]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of plasminogen activation [GO:0010757]; positive regulation of extracellular matrix constituent secretion [GO:0003331]; proteolysis [GO:0006508]; regulation of complement activation [GO:0030449]; response to drug [GO:0042493]; response to heat [GO:0009408]	extracellular space [GO:0005615]	cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2pj4b__d2odfd___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]		extracellular space [GO:0005615]		metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	
d2pjab__d1gytd2__1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	proteolysis [GO:0006508]	peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	extracellular space [GO:0005615]	cytoplasm [GO:0005737]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]
d2pjbb__d1h8la2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	integral component of membrane [GO:0016021]; metallocarboxypeptidase activity [GO:0004181]; serine-type carboxypeptidase activity [GO:0004185]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	integral component of membrane [GO:0016021]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; serine-type carboxypeptidase activity [GO:0004185]; zinc ion binding [GO:0008270]
d2pjhb1_d1ti6c1__1	Metazoa		Chordata		ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	
d2pjkc__d1jljc___1		Metazoa		Chordata		cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin cofactor binding [GO:0043546]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; response to metal ion [GO:0010038]		establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; response to metal ion [GO:0010038]		cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin cofactor binding [GO:0043546]; molybdopterin molybdotransferase activity [GO:0061599]; nitrate reductase activity [GO:0008940]
d2pk0a1_d3fxma1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; protein serine/threonine phosphatase activity [GO:0004722]	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; calmodulin-dependent protein phosphatase activity [GO:0033192]; magnesium ion binding [GO:0000287]; magnesium-dependent protein serine/threonine phosphatase activity [GO:0004724]; manganese ion binding [GO:0030145]; protein serine/threonine phosphatase activity [GO:0004722]; R-SMAD binding [GO:0070412]; cell cycle arrest [GO:0007050]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dephosphorylation [GO:0016311]; N-terminal protein myristoylation [GO:0006499]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of transcription, DNA-templated [GO:0045893]; protein dephosphorylation [GO:0006470]		cell cycle arrest [GO:0007050]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dephosphorylation [GO:0016311]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; N-terminal protein myristoylation [GO:0006499]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of transcription, DNA-templated [GO:0045893]; protein dephosphorylation [GO:0006470]		cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; protein serine/threonine phosphatase activity [GO:0004722]	calmodulin-dependent protein phosphatase activity [GO:0033192]; magnesium-dependent protein serine/threonine phosphatase activity [GO:0004724]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; protein serine/threonine phosphatase activity [GO:0004722]; R-SMAD binding [GO:0070412]
d2pk0b1_d4rafa1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; protein serine/threonine phosphatase activity [GO:0004722]	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; calmodulin-dependent protein phosphatase activity [GO:0033192]; magnesium ion binding [GO:0000287]; magnesium-dependent protein serine/threonine phosphatase activity [GO:0004724]; manganese ion binding [GO:0030145]; protein serine/threonine phosphatase activity [GO:0004722]; R-SMAD binding [GO:0070412]; cell cycle arrest [GO:0007050]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dephosphorylation [GO:0016311]; N-terminal protein myristoylation [GO:0006499]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of transcription, DNA-templated [GO:0045893]; protein dephosphorylation [GO:0006470]		cell cycle arrest [GO:0007050]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dephosphorylation [GO:0016311]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; N-terminal protein myristoylation [GO:0006499]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of transcription, DNA-templated [GO:0045893]; protein dephosphorylation [GO:0006470]		cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; protein serine/threonine phosphatase activity [GO:0004722]	calmodulin-dependent protein phosphatase activity [GO:0033192]; magnesium-dependent protein serine/threonine phosphatase activity [GO:0004724]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; protein serine/threonine phosphatase activity [GO:0004722]; R-SMAD binding [GO:0070412]
d2pk2d1_d5nevd1__1	Metazoa	Metazoa	Chordata	Chordata	cyclin/CDK positive transcription elongation factor complex [GO:0008024]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 7SK snRNA binding [GO:0097322]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; DNA binding [GO:0003677]; protein kinase binding [GO:0019901]; RNA polymerase binding [GO:0070063]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of mRNA polyadenylation [GO:1900364]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of mRNA polyadenylation [GO:1900364]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cyclin/CDK positive transcription elongation factor complex [GO:0008024]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	7SK snRNA binding [GO:0097322]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; DNA binding [GO:0003677]; protein kinase binding [GO:0019901]; RNA polymerase binding [GO:0070063]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2pk6a__d2qzwa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; aspartic-type endopeptidase activity [GO:0004190]; adhesion of symbiont to host [GO:0044406]; fungal-type cell wall organization [GO:0031505]; induction by symbiont of defense-related host calcium ion flux [GO:0052391]; induction by symbiont of host defense response [GO:0044416]; induction by symbiont of host immune response [GO:0052559]; nitrogen compound metabolic process [GO:0006807]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; protein metabolic process [GO:0019538]; proteolysis [GO:0006508]; signal peptide processing [GO:0006465]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	adhesion of symbiont to host [GO:0044406]; fungal-type cell wall organization [GO:0031505]; induction by symbiont of defense-related host calcium ion flux [GO:0052391]; induction by symbiont of host defense response [GO:0044416]; induction by symbiont of host immune response [GO:0052559]; nitrogen compound metabolic process [GO:0006807]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; protein metabolic process [GO:0019538]; proteolysis [GO:0006508]; signal peptide processing [GO:0006465]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2pk6b__d5dq2a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2pka.1_d3osye1__1	Metazoa		Chordata		secretory granule [GO:0030141]; serine-type endopeptidase activity [GO:0004252]; regulation of systemic arterial blood pressure [GO:0003073]; zymogen activation [GO:0031638]	cysteine-type endopeptidase activity [GO:0004197]	regulation of systemic arterial blood pressure [GO:0003073]; zymogen activation [GO:0031638]		secretory granule [GO:0030141]		serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]
d2pkfb1_d5eyna___1			Actinobacteria	Proteobacteria	plasma membrane [GO:0005886]; adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; carbohydrate kinase activity [GO:0019200]; dGTP binding [GO:0032567]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]	fructokinase activity [GO:0008865]; nucleotide binding [GO:0000166]	AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]		plasma membrane [GO:0005886]		adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; carbohydrate kinase activity [GO:0019200]; dGTP binding [GO:0032567]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	fructokinase activity [GO:0008865]; nucleotide binding [GO:0000166]
d2pkqt2_d4dbvo2__1	Viridiplantae		Streptophyta	Firmicutes	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2pkrl2_d1i32a2__1	Viridiplantae		Streptophyta		chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	chloroplast [GO:0009507]	glycosome [GO:0020015]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2pkrl2_d1yl7g2__1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	chloroplast [GO:0009507]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [GO:0016726]
d2pkyx__d5tnfb___1			Proteobacteria	Proteobacteria	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	hydrolase activity [GO:0016787]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]				haloalkane dehalogenase activity [GO:0018786]	hydrolase activity [GO:0016787]
d2pl5a1_d4dnqb___1		Viridiplantae	Spirochaetes	Streptophyta	cytoplasm [GO:0005737]; homoserine O-acetyltransferase activity [GO:0004414]; homoserine metabolic process [GO:0009092]; methionine biosynthetic process [GO:0009086]	hydrolase activity, acting on ester bonds [GO:0016788]; secondary shoot formation [GO:0010223]; strigolactone biosynthetic process [GO:1901601]	homoserine metabolic process [GO:0009092]; methionine biosynthetic process [GO:0009086]	secondary shoot formation [GO:0010223]; strigolactone biosynthetic process [GO:1901601]	cytoplasm [GO:0005737]		homoserine O-acetyltransferase activity [GO:0004414]	hydrolase activity, acting on ester bonds [GO:0016788]
d2pl6b__d2gvmc___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; spore wall [GO:0031160]	cell wall [GO:0005618]; extracellular region [GO:0005576]			extracellular region [GO:0005576]; spore wall [GO:0031160]	cell wall [GO:0005618]; extracellular region [GO:0005576]		
d2pl9a__d1fqwa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	metal ion binding [GO:0046872]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d2pl9a__d1zita___1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]		metal ion binding [GO:0046872]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d2pl9b__d1oxkh___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]; osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	metal ion binding [GO:0046872]	histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]
d2pl9b__d4qpjc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; peptidyl-aspartic acid modification [GO:0018197]; phosphorelay signal transduction system [GO:0000160]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	peptidyl-aspartic acid modification [GO:0018197]; phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]
d2plfa2_d3wxmc3__1			Crenarchaeota	Crenarchaeota	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2plv3__d1pgl11__1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	transport of virus in host, cell to cell [GO:0046740]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2plv3__d2hwc.1__1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2plxa1_d3vb3b___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2pmca__d1w25a1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]
d2pmcc__d3cz5c___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]		metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d2pmcd__d2hqra1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]		metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d2pmpa__d3p10a___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; carotenoid biosynthetic process [GO:0016117]; chlorophyll biosynthetic process [GO:0015995]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	carotenoid biosynthetic process [GO:0016117]; chlorophyll biosynthetic process [GO:0015995]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]		2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d2pmra1_d2oo2a1__1			Euryarchaeota	Euryarchaeota								
d2pmtb1_d5f06a2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]		glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2pmtb2_d3gurd1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]		cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	glutathione transferase activity [GO:0004364]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]
d2pmtc1_d2r6ka1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione transferase activity [GO:0004364]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2pmtd2_d1kbnb2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2pmua__d2ff4a1__1		Fungi	Actinobacteria	Ascomycota	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	chromatin [GO:0000785]; nucleus [GO:0005634]; double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; histone binding [GO:0042393]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; G1 DNA damage checkpoint [GO:0044783]; intra-S DNA damage checkpoint [GO:0031573]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of DNA replication [GO:0008156]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; G1 DNA damage checkpoint [GO:0044783]; intra-S DNA damage checkpoint [GO:0031573]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of DNA replication [GO:0008156]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]		chromatin [GO:0000785]; nucleus [GO:0005634]	DNA binding [GO:0003677]	double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; histone binding [GO:0042393]
d2pmub__d1opca___1			Actinobacteria	Proteobacteria	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]	DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2pn8b1_d3p7xb___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	thioredoxin peroxidase activity [GO:0008379]
d2pn8c1_d5ecmb1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2pn8d1_d3u5rf___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]
d2pn8g1_d4ri6b1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cytoplasm [GO:0005737]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2pn8h1_d4in0b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; cell cycle [GO:0007049]; mRNA splicing, via spliceosome [GO:0000398]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell cycle [GO:0007049]; mRNA splicing, via spliceosome [GO:0000398]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	
d2pn8j1_d5a5kj1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d2pnfa__d4qo7b1__1		Metazoa	Aquificae	Chordata	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2pnfb__d4i9uc1__1		Metazoa	Aquificae	Chordata	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	L-lactate dehydrogenase activity [GO:0004459]
d2pnre1_d3tz5a1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; glucose metabolic process [GO:0006006]; hypoxia-inducible factor-1alpha signaling pathway [GO:0097411]; peptidyl-serine phosphorylation [GO:0018105]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of glucose metabolic process [GO:0010906]; regulation of reactive oxygen species metabolic process [GO:2000377]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrion [GO:0005739]; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity [GO:0047323]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; glucose metabolic process [GO:0006006]; hypoxia-inducible factor-1alpha signaling pathway [GO:0097411]; peptidyl-serine phosphorylation [GO:0018105]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of glucose metabolic process [GO:0010906]; regulation of reactive oxygen species metabolic process [GO:2000377]	branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740]	[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity [GO:0047323]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]
d2pnzb1_d3jb9b5__1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; post-mRNA release spliceosomal complex [GO:0071014]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387]	RNA catabolic process [GO:0006401]	mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; post-mRNA release spliceosomal complex [GO:0071014]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]	3'-5'-exoribonuclease activity [GO:0000175]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d2po0a1_d2avye1__1			Euryarchaeota		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]		RNA catabolic process [GO:0006401]		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]		3'-5'-exoribonuclease activity [GO:0000175]	
d2po0a2_d2br2e2__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2po0a2_d2c39d2__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2po1a2_d2wnrd2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	RNA catabolic process [GO:0006401]	RNA catabolic process [GO:0006401]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2po1b1_d4u3ba2__1			Euryarchaeota	Aquificae	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	RNA catabolic process [GO:0006401]	lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]		3'-5'-exoribonuclease activity [GO:0000175]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d2po2a2_d2br2i2__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2po2b2_d2c38j2__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2po6a1_d2i9la1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2po6a1_d4rnrb2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2po6b1_d1kj2e___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2po6e2_d2vaaa2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2po6f1_d2ny6c2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d2po7a__d3w1wa___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d2po7b__d1n0ia___1	Metazoa		Chordata	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	heme biosynthetic process [GO:0006783]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]
d2pooa__d1qlga___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; 3-phytase activity [GO:0016158]	extracellular region [GO:0005576]; 3-phytase activity [GO:0016158]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	3-phytase activity [GO:0016158]	3-phytase activity [GO:0016158]
d2pova__d4xz5c___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2pp7a1_d3heij1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	periplasmic space [GO:0042597]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]
d2pp7b1_d3ryma___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2pp7c1_d2w8cb___1			Proteobacteria	Cyanobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	thylakoid membrane [GO:0042651]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2pp8a2_d1jxga___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2pp8b1_d3v9ca1__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2pp8c1_d1bq5a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2pp9a1_d3pxla2__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2pp9b2_d3cvda___1			Proteobacteria	Cyanobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	thylakoid membrane [GO:0042651]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2pp9c1_d3ppsb2__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2ppaa1_d2zxwo2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2ppaa2_d1etjc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2ppac1_d1nwpa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2ppbo__d2a68o___1			Deinococcus-Thermus	Deinococcus-Thermus	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]			DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d2ppcb1_d5i6la1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ppcb2_d4knse2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ppcc1_d4ko6c___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2ppda1_d1mzza1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ppda2_d1n70a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ppdc2_d3wg7o2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2ppea1_d2pp7a2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ppea1_d5u7ne___1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2ppeb2_d4knta1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ppfa1_d2pp8b2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ppfa1_d5iy5o2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2ppfb1_d3h4fa1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ppfc1_d2xx1c1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ppha1_d2kfkb1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; activation of protein kinase activity [GO:0032147]; blood vessel development [GO:0001568]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; negative regulation of cellular senescence [GO:2000773]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of p38MAPK cascade [GO:1900745]; protein autophosphorylation [GO:0046777]; signal transduction by protein phosphorylation [GO:0023014]	Cdc24p-Far1p-Gbetagamma complex [GO:0120171]; cell division site [GO:0032153]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; division septum [GO:0000935]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]; nucleus [GO:0005634]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; cellular bud site selection [GO:0000282]; chemotropism [GO:0043577]; protein localization to cell cortex [GO:0072697]; regulation of exit from mitosis [GO:0007096]; regulation of Rho protein signal transduction [GO:0035023]; septin ring organization [GO:0031106]; small GTPase mediated signal transduction [GO:0007264]	activation of protein kinase activity [GO:0032147]; blood vessel development [GO:0001568]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; negative regulation of cellular senescence [GO:2000773]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of p38MAPK cascade [GO:1900745]; protein autophosphorylation [GO:0046777]; signal transduction by protein phosphorylation [GO:0023014]	cellular bud site selection [GO:0000282]; chemotropism [GO:0043577]; protein localization to cell cortex [GO:0072697]; regulation of exit from mitosis [GO:0007096]; regulation of Rho protein signal transduction [GO:0035023]; septin ring organization [GO:0031106]; small GTPase mediated signal transduction [GO:0007264]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	Cdc24p-Far1p-Gbetagamma complex [GO:0120171]; cell division site [GO:0032153]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; division septum [GO:0000935]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]; nucleus [GO:0005634]	ATP binding [GO:0005524]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	Rho guanyl-nucleotide exchange factor activity [GO:0005089]
d2pq3a__d4m2oa___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; calcium ion binding [GO:0005509]; phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]	calcium ion binding [GO:0005509]
d2pq3a__d4upga___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]; action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	action potential [GO:0001508]; calcium ion transport [GO:0006816]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart development [GO:0007507]; intracellular sequestering of iron ion [GO:0006880]; muscle organ development [GO:0007517]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of heart rate [GO:0010459]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart contraction [GO:0008016]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of relaxation of muscle [GO:1901077]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of striated muscle contraction [GO:0006942]; signal transduction [GO:0007165]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine neck [GO:0044326]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; Z disc [GO:0030018]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]	calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; repressing transcription factor binding [GO:0070491]; signaling receptor binding [GO:0005102]
d2pqab__d1ph4a2__1	Metazoa		Chordata	Ciliophora	DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; single-stranded DNA binding [GO:0003697]; base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	telomere capping [GO:0016233]	DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	damaged DNA binding [GO:0003684]; single-stranded DNA binding [GO:0003697]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d2pqma1_d2jc3a___1				Proteobacteria	cysteine synthase activity [GO:0004124]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]		cytoplasm [GO:0005737]	cysteine synthase activity [GO:0004124]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]
d2pqna__d1zb1b___1	Fungi	Fungi	Ascomycota	Ascomycota	integral component of mitochondrial outer membrane [GO:0031307]; integral component of peroxisomal membrane [GO:0005779]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; apoptotic process [GO:0006915]; autophagy of mitochondrion [GO:0000422]; chronological cell aging [GO:0001300]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; peroxisome fission [GO:0016559]; peroxisome organization [GO:0007031]; positive regulation of mitochondrial fission [GO:0090141]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; deubiquitinase activator activity [GO:0035800]; ATP export [GO:1904669]; intralumenal vesicle formation [GO:0070676]; mitochondria-associated ubiquitin-dependent protein catabolic process [GO:0072671]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; protein deubiquitination [GO:0016579]; protein localization to endosome [GO:0036010]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; response to nutrient [GO:0007584]; ubiquitin-dependent protein catabolic process [GO:0006511]; vacuolar transport [GO:0007034]	apoptotic process [GO:0006915]; autophagy of mitochondrion [GO:0000422]; chronological cell aging [GO:0001300]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; peroxisome fission [GO:0016559]; peroxisome organization [GO:0007031]; positive regulation of mitochondrial fission [GO:0090141]	ATP export [GO:1904669]; intralumenal vesicle formation [GO:0070676]; mitochondria-associated ubiquitin-dependent protein catabolic process [GO:0072671]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; protein deubiquitination [GO:0016579]; protein localization to endosome [GO:0036010]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; response to nutrient [GO:0007584]; ubiquitin-dependent protein catabolic process [GO:0006511]; vacuolar transport [GO:0007034]	integral component of mitochondrial outer membrane [GO:0031307]; integral component of peroxisomal membrane [GO:0005779]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]		deubiquitinase activator activity [GO:0035800]
d2pqsb1_d3cqob2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; membrane [GO:0016020]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338]	metal ion binding [GO:0046872]	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338]		extracellular region [GO:0005576]; membrane [GO:0016020]			metal ion binding [GO:0046872]
d2pr4l1_d1lnud1__1		Metazoa		Chordata		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d2pr4l2_d4m1dm2__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d2pr5a__d4bbva___1			Firmicutes	Proteobacteria	photoreceptor activity [GO:0009881]; protein-chromophore linkage [GO:0018298]; response to stimulus [GO:0050896]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	protein-chromophore linkage [GO:0018298]; response to stimulus [GO:0050896]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			photoreceptor activity [GO:0009881]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d2pr6b__d1s4sa___1			Firmicutes	Proteobacteria	photoreceptor activity [GO:0009881]; protein-chromophore linkage [GO:0018298]; response to stimulus [GO:0050896]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	protein-chromophore linkage [GO:0018298]; response to stimulus [GO:0050896]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			photoreceptor activity [GO:0009881]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d2preb__d3bwka___1	Viridiplantae		Streptophyta	Apicomplexa	cysteine-type peptidase activity [GO:0008234]	integral component of membrane [GO:0016021]; cysteine-type peptidase activity [GO:0008234]				integral component of membrane [GO:0016021]	cysteine-type peptidase activity [GO:0008234]	cysteine-type peptidase activity [GO:0008234]
d2preb__d5w8uc2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cysteine-type peptidase activity [GO:0008234]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cysteine-type peptidase activity [GO:0008234]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2prfa__d3davb___1		Fungi		Ascomycota	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; actin monomer binding [GO:0003785]; actin cytoskeleton organization [GO:0030036]	actin cortical patch [GO:0030479]; cell [GO:0005623]; cell cortex [GO:0005938]; cell cortex of cell tip [GO:0051285]; mating projection tip [GO:0043332]; medial cortex [GO:0031097]; actin monomer binding [GO:0003785]; guanyl-nucleotide exchange factor activity [GO:0005085]; actin cortical patch organization [GO:0044396]; actin filament polymerization [GO:0030041]; cytogamy [GO:0000755]; mitotic actomyosin contractile ring assembly [GO:1903475]; negative regulation of actin filament binding [GO:1904530]; negative regulation of actin filament polymerization [GO:0030837]; regulation of barbed-end actin filament capping [GO:2000812]; sequestering of actin monomers [GO:0042989]	actin cytoskeleton organization [GO:0030036]	actin cortical patch organization [GO:0044396]; actin filament polymerization [GO:0030041]; cytogamy [GO:0000755]; mitotic actomyosin contractile ring assembly [GO:1903475]; negative regulation of actin filament binding [GO:1904530]; negative regulation of actin filament polymerization [GO:0030837]; regulation of barbed-end actin filament capping [GO:2000812]; sequestering of actin monomers [GO:0042989]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]	actin cortical patch [GO:0030479]; cell [GO:0005623]; cell cortex [GO:0005938]; cell cortex of cell tip [GO:0051285]; mating projection tip [GO:0043332]; medial cortex [GO:0031097]	actin monomer binding [GO:0003785]	actin monomer binding [GO:0003785]; guanyl-nucleotide exchange factor activity [GO:0005085]
d2prga__d3m7ra___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]; activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	cell [GO:0005623]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]; calcitriol binding [GO:1902098]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; lithocholic acid binding [GO:1902121]; lithocholic acid receptor activity [GO:0038186]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; vitamin D binding [GO:0005499]; zinc ion binding [GO:0008270]; animal organ morphogenesis [GO:0009887]; bile acid signaling pathway [GO:0038183]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cell morphogenesis [GO:0000902]; cellular calcium ion homeostasis [GO:0006874]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; decidualization [GO:0046697]; intestinal absorption [GO:0050892]; lactation [GO:0007595]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; mammary gland branching involved in pregnancy [GO:0060745]; multicellular organism development [GO:0007275]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process involved in mammary gland involution [GO:0060058]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vitamin D 24-hydroxylase activity [GO:0010980]; regulation of calcidiol 1-monooxygenase activity [GO:0060558]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; transcription initiation from RNA polymerase II promoter [GO:0006367]; vitamin D metabolic process [GO:0042359]; vitamin D receptor signaling pathway [GO:0070561]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	animal organ morphogenesis [GO:0009887]; bile acid signaling pathway [GO:0038183]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cell morphogenesis [GO:0000902]; cellular calcium ion homeostasis [GO:0006874]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; decidualization [GO:0046697]; intestinal absorption [GO:0050892]; lactation [GO:0007595]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; mammary gland branching involved in pregnancy [GO:0060745]; multicellular organism development [GO:0007275]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process involved in mammary gland involution [GO:0060058]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vitamin D 24-hydroxylase activity [GO:0010980]; regulation of calcidiol 1-monooxygenase activity [GO:0060558]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; transcription initiation from RNA polymerase II promoter [GO:0006367]; vitamin D metabolic process [GO:0042359]; vitamin D receptor signaling pathway [GO:0070561]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]	cell [GO:0005623]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]	activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	calcitriol binding [GO:1902098]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; lithocholic acid binding [GO:1902121]; lithocholic acid receptor activity [GO:0038186]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; vitamin D binding [GO:0005499]; zinc ion binding [GO:0008270]
d2prla__d2j6xa___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]		cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]		dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2prla__d3w7na___1	Metazoa		Chordata		cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]	'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d2prma__d3n19b___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]		cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]		dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d2prqa__d3hlpb___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]			extracellular region [GO:0005576]	extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2ps1a__d1ecga1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; orotate phosphoribosyltransferase activity [GO:0004588]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine nucleotide biosynthetic process [GO:0006221]; pyrimidine ribonucleoside biosynthetic process [GO:0046132]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine nucleotide biosynthetic process [GO:0006221]; pyrimidine ribonucleoside biosynthetic process [GO:0046132]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	orotate phosphoribosyltransferase activity [GO:0004588]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]
d2ps2a2_d2qddb2__1	Fungi		Ascomycota	Proteobacteria	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2ps2c2_d2pu0a1__1	Fungi		Ascomycota		metal ion binding [GO:0046872]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2ps5b__d4kq5a___1	Fungi	Metazoa	Ascomycota	Chordata	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	sesquiterpenoid biosynthetic process [GO:0016106]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2ps7b__d1yyra___1	Fungi	Fungi	Ascomycota	Ascomycota	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]			metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]
d2ps8b__d1jfga___1	Fungi	Fungi	Ascomycota	Ascomycota	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]	sesquiterpenoid biosynthetic process [GO:0016106]			metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]
d2ps8b__d2onhb2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	sesquiterpenoid biosynthetic process [GO:0016106]				metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]	magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d2psea__d1ys1x___1	Metazoa		Cnidaria	Proteobacteria	carboxy-lyase activity [GO:0016831]; Renilla-luciferin 2-monooxygenase activity [GO:0050248]; bioluminescence [GO:0008218]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	bioluminescence [GO:0008218]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	carboxy-lyase activity [GO:0016831]; Renilla-luciferin 2-monooxygenase activity [GO:0050248]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d2psfb__d2oqid2__1	Metazoa	Metazoa	Cnidaria	Chordata	carboxy-lyase activity [GO:0016831]; Renilla-luciferin 2-monooxygenase activity [GO:0050248]; bioluminescence [GO:0008218]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	bioluminescence [GO:0008218]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	carboxy-lyase activity [GO:0016831]; Renilla-luciferin 2-monooxygenase activity [GO:0050248]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2psmb2_d1ik0a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; interleukin-15 receptor activity [GO:0042010]; protein kinase binding [GO:0019901]; interleukin-15-mediated signaling pathway [GO:0035723]; negative regulation of neuron projection development [GO:0010977]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of phagocytosis [GO:0050766]; receptor signaling pathway via JAK-STAT [GO:0007259]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	interleukin-15-mediated signaling pathway [GO:0035723]; negative regulation of neuron projection development [GO:0010977]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of phagocytosis [GO:0050766]; receptor signaling pathway via JAK-STAT [GO:0007259]	cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	interleukin-15 receptor activity [GO:0042010]; protein kinase binding [GO:0019901]	cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]
d2psna1_d1sjdd2__1	Metazoa		Chordata	Actinobacteria	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	menaquinone biosynthetic process [GO:0009234]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d2psnc2_d3pwia2__1	Metazoa		Chordata	Proteobacteria	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	D-glucarate catabolic process [GO:0042838]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d2psnd1_d3ujsa1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2psra__d2wcfb1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d2psxa__d1svpa___1	Metazoa		Chordata		cytosol [GO:0005829]; epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; cornification [GO:0070268]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	amelogenesis [GO:0097186]; cornification [GO:0070268]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]
d2psya__d3d65e___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; cornification [GO:0070268]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	amelogenesis [GO:0097186]; cornification [GO:0070268]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]	digestion [GO:0007586]; proteolysis [GO:0006508]	cytosol [GO:0005829]; epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2psza__d2gwoc___1		Metazoa	Firmicutes	Chordata	protein tyrosine phosphatase activity [GO:0004725]	phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dephosphorylation [GO:0016311]; meiotic cell cycle [GO:0051321]; protein dephosphorylation [GO:0006470]; spermatogenesis [GO:0007283]		dephosphorylation [GO:0016311]; meiotic cell cycle [GO:0051321]; protein dephosphorylation [GO:0006470]; spermatogenesis [GO:0007283]			protein tyrosine phosphatase activity [GO:0004725]	phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d2pt1a__d1a54a___1			Cyanobacteria	Proteobacteria	plasma membrane [GO:0005886]; thylakoid membrane [GO:0042651]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	plasma membrane [GO:0005886]; thylakoid membrane [GO:0042651]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]	phosphate ion binding [GO:0042301]
d2pt2a__d3axfb___1			Cyanobacteria	Proteobacteria	plasma membrane [GO:0005886]; thylakoid membrane [GO:0042651]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	outer membrane-bounded periplasmic space [GO:0030288]; ATPase-coupled molybdate transmembrane transporter activity [GO:0015412]; molybdate ion binding [GO:0030973]; molybdenum ion binding [GO:0030151]; tungstate binding [GO:1901359]; molybdate ion transport [GO:0015689]; response to chromate [GO:0046687]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	molybdate ion transport [GO:0015689]; response to chromate [GO:0046687]	plasma membrane [GO:0005886]; thylakoid membrane [GO:0042651]	outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]	ATPase-coupled molybdate transmembrane transporter activity [GO:0015412]; molybdate ion binding [GO:0030973]; molybdenum ion binding [GO:0030151]; tungstate binding [GO:1901359]
d2pt2a__d5mm3b___1			Cyanobacteria	Proteobacteria	plasma membrane [GO:0005886]; thylakoid membrane [GO:0042651]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	plasma membrane [GO:0005886]; thylakoid membrane [GO:0042651]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d2pt6b__d1zdzb___1			Apicomplexa		cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]		polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]		cytosol [GO:0005829]		spermidine synthase activity [GO:0004766]	
d2pt9a__d3c3yb___1		Viridiplantae	Apicomplexa	Streptophyta	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]		cytosol [GO:0005829]		spermidine synthase activity [GO:0004766]	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]
d2pt9b__d5n5db1__1			Apicomplexa	Actinobacteria	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	O-methyltransferase activity [GO:0008171]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]		cytosol [GO:0005829]		spermidine synthase activity [GO:0004766]	O-methyltransferase activity [GO:0008171]
d2ptda__d1ptda___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]
d2ptqb1_d1hy1a___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity [GO:0070626]; N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity [GO:0004018]; 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	cytosol [GO:0005829]		(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity [GO:0070626]; N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity [GO:0004018]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]
d2ptxa2_d3dfyi1__1				Thermotogae	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	glycolytic process [GO:0006096]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d2ptza1_d5j04b2__1				Cyanobacteria	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2pu0a2_d1kczb2__1				Firmicutes	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]; glutamate catabolic process via L-citramalate [GO:0019553]	glycolytic process [GO:0006096]	glutamate catabolic process via L-citramalate [GO:0019553]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]
d2pu1a1_d5eu9h2__1		Metazoa		Chordata	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2pu1a2_d3dg7b1__1				Actinobacteria	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	glycolytic process [GO:0006096]		ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d2pu6a__d6esja___1		Metazoa		Chordata		blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]		choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]		blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]		acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]
d2pu7a__d5ct4a___1			Proteobacteria	Firmicutes	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; aromatic compound catabolic process [GO:0019439]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	aromatic compound catabolic process [GO:0019439]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d2puea2_d2fn9a___1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]; negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]		negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]		cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]	
d2puha__d1uk8a___1			Proteobacteria	Proteobacteria	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; aromatic compound catabolic process [GO:0019439]	hydrolase activity [GO:0016787]	aromatic compound catabolic process [GO:0019439]				2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]	hydrolase activity [GO:0016787]
d2puob__d2pvgb___1			Cyanobacteria	Cyanobacteria	oxidoreductase activity [GO:0016491]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]	oxidoreductase activity [GO:0016491]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]			oxidoreductase activity [GO:0016491]	oxidoreductase activity [GO:0016491]
d2putb__d1hoxb___1	Fungi	Metazoa	Ascomycota	Chordata	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; cell wall chitin biosynthetic process [GO:0006038]; cellular response to drug [GO:0035690]; chitin biosynthetic process [GO:0006031]; fructose 6-phosphate metabolic process [GO:0006002]; fungal-type cell wall chitin biosynthetic process [GO:0034221]; glucosamine biosynthetic process [GO:0006042]; glutamine metabolic process [GO:0006541]; hyphal growth [GO:0030448]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cellular response to drug [GO:0035690]; cell wall chitin biosynthetic process [GO:0006038]; chitin biosynthetic process [GO:0006031]; fructose 6-phosphate metabolic process [GO:0006002]; fungal-type cell wall chitin biosynthetic process [GO:0034221]; glucosamine biosynthetic process [GO:0006042]; glutamine metabolic process [GO:0006541]; hyphal growth [GO:0030448]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]; extracellular space [GO:0005615]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]
d2pv1a__d3kada2__1		Metazoa	Firmicutes	Chordata	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]		cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	transferase activity [GO:0016740]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]
d2pvaa__d2z71c___1			Firmicutes	Firmicutes	penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]	penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]			penicillin amidase activity [GO:0008953]	penicillin amidase activity [GO:0008953]
d2pvad__d2iwmc___1			Firmicutes	Firmicutes	penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]	penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]			penicillin amidase activity [GO:0008953]	penicillin amidase activity [GO:0008953]
d2pvba__d1rjva___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]; calcium ion binding [GO:0005509]	axon [GO:0030424]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cochlea development [GO:0090102]		cochlea development [GO:0090102]	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]	axon [GO:0030424]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d2pvdb__d2pukf___1		Viridiplantae	Cyanobacteria	Streptophyta	oxidoreductase activity [GO:0016491]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]	cell [GO:0005623]; chloroplast [GO:0009507]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]; chloroplast [GO:0009507]	oxidoreductase activity [GO:0016491]	protein disulfide oxidoreductase activity [GO:0015035]
d2pvgc__d3p4pn1__1			Cyanobacteria	Proteobacteria	oxidoreductase activity [GO:0016491]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d2pvqa1_d2v32c___1		Metazoa	Proteobacteria	Annelida	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]	cell [GO:0005623]	glutathione transferase activity [GO:0004364]	peroxiredoxin activity [GO:0051920]
d2pvqa1_d5a5ka1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	glutathione transferase activity [GO:0004364]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d2pvqa2_d5a5ku2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	glutathione transferase activity [GO:0004364]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d2pvua__d1jvxa___1			Firmicutes	Proteobacteria	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	membrane [GO:0016020]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ligand-gated ion channel activity [GO:0015276]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d2pvua__d5teub1__1			Firmicutes	Proteobacteria	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]			membrane [GO:0016020]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	ligand-gated ion channel activity [GO:0015276]	metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]
d2pw0b1_d2q9ha2__1			Proteobacteria	Proteobacteria	intramolecular oxidoreductase activity, transposing C=C bonds [GO:0016863]; propionate catabolic process, 2-methylcitrate cycle [GO:0019629]	cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	propionate catabolic process, 2-methylcitrate cycle [GO:0019629]	lysine biosynthetic process via diaminopimelate [GO:0009089]		cytosol [GO:0005829]	intramolecular oxidoreductase activity, transposing C=C bonds [GO:0016863]	diaminopimelate epimerase activity [GO:0008837]
d2pw2b1_d5o02c1__1												
d2pw3a__d3jswa1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2pwaa__d1ga6a___1	Fungi		Ascomycota	Proteobacteria	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]				periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2pwaa__d4rydd1__1	Fungi	Metazoa	Ascomycota	Chordata	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d2pwba__d1gcia___1	Fungi		Ascomycota	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2pwba__d1gtl1___1	Fungi		Ascomycota	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2pwcb__d5kaoa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2pwdb1_d3sepb3__1			Proteobacteria	Proteobacteria	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2pwdb2_d1pifa1__1		Metazoa	Proteobacteria	Chordata	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]		extracellular space [GO:0005615]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d2pweb1_d1bgab___1			Proteobacteria	Firmicutes	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]			isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d2pweb2_d3h55b2__1		Metazoa	Proteobacteria	Chordata	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d2pwga1_d1dedb4__1			Proteobacteria	Firmicutes	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2pwga1_d4jcla1__1			Proteobacteria	Firmicutes	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2pwhb1_d2wc4d___1			Proteobacteria	Thermotogae	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]			isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d2pwmd__d1afva___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2pwra__d5p7pa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2pwrb__d5oz2a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2pwsa__d1rgbl1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; host cell postsynaptic membrane [GO:0035792]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; hemolysis in other organism [GO:0044179]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; hemolysis in other organism [GO:0044179]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell postsynaptic membrane [GO:0035792]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d2pwya__d2ckdb___1			Deinococcus-Thermus	Actinobacteria	tRNA (m1A) methyltransferase complex [GO:0031515]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]; tRNA methylation [GO:0030488]	methyltransferase activity [GO:0008168]	tRNA methylation [GO:0030488]		tRNA (m1A) methyltransferase complex [GO:0031515]		tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]	methyltransferase activity [GO:0008168]
d2pwyb__d2pwpa___1			Deinococcus-Thermus	Apicomplexa	tRNA (m1A) methyltransferase complex [GO:0031515]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]; tRNA methylation [GO:0030488]	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	tRNA methylation [GO:0030488]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	tRNA (m1A) methyltransferase complex [GO:0031515]	cytosol [GO:0005829]	tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]	spermidine synthase activity [GO:0004766]
d2pwyb__d3ha3a___1			Deinococcus-Thermus	Actinobacteria	tRNA (m1A) methyltransferase complex [GO:0031515]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]; tRNA methylation [GO:0030488]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; methyltransferase activity [GO:0008168]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; mycolic acid biosynthetic process [GO:0071768]	tRNA methylation [GO:0030488]	mycolic acid biosynthetic process [GO:0071768]	tRNA (m1A) methyltransferase complex [GO:0031515]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]	methyltransferase activity [GO:0008168]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d2pwza1_d1p44b___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d2pwza2_d1t2fc2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; identical protein binding [GO:0042802]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; pyruvate metabolic process [GO:0006090]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; pyruvate metabolic process [GO:0006090]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	identical protein binding [GO:0042802]; L-lactate dehydrogenase activity [GO:0004459]
d2pwze2_d2v6mb2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	L-lactate dehydrogenase activity [GO:0004459]
d2pwzg1_d2cfcc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	2-(R)-hydroxypropyl-CoM dehydrogenase activity [GO:0050574]; propylene catabolic process [GO:0042208]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	propylene catabolic process [GO:0042208]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]		L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	2-(R)-hydroxypropyl-CoM dehydrogenase activity [GO:0050574]
d2pwzg2_d3om9a2__1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]		L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d2px5a__d3elya___1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]
d2px5b__d5fhrb___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d2pxha1_d1n75a2__1			Euryarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	tyrosyl-tRNA aminoacylation [GO:0006437]	glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2pxyb__d2f54b2__1	Metazoa	Metazoa	Chordata	Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]		
d2pxyb__d5x08l1__1	Metazoa		Chordata			host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; entry into host cell [GO:0030260]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; entry into host cell [GO:0030260]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d2pxyd1_d3d2ud1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2pxyd1_d3kpse2__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2pxyd2_d2bsta2__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2pxzx2_d4gmwa1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]; gluconeogenesis [GO:0006094]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	gluconeogenesis [GO:0006094]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphoenolpyruvate carboxykinase (ATP) activity [GO:0004612]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]
d2py0a1_d1rg0b1__1			Proteobacteria	Proteobacteria	pilus [GO:0009289]; cell adhesion [GO:0007155]	periplasmic space [GO:0042597]; pilus [GO:0009289]; glycosphingolipid binding [GO:0043208]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	pilus [GO:0009289]	periplasmic space [GO:0042597]; pilus [GO:0009289]		glycosphingolipid binding [GO:0043208]
d2py0a1_d1t92b1__1			Proteobacteria	Proteobacteria	pilus [GO:0009289]; cell adhesion [GO:0007155]	type II protein secretion system complex [GO:0015627]; protein secretion by the type II secretion system [GO:0015628]	cell adhesion [GO:0007155]	protein secretion by the type II secretion system [GO:0015628]	pilus [GO:0009289]	type II protein secretion system complex [GO:0015627]		
d2py2f__d2orja1__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]		cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]		clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d2py8a1_d3q20b___1			Cyanobacteria	Cyanobacteria								
d2pyba__d1mfrm___1		Metazoa	Spirochaetes	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2pyeb2_d3efdl1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]			
d2pyeb2_d4o5ll2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]			
d2pyfa1_d3lkpb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2pyfb1_d4p5kd2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d2pyla1_d5hbma2__1					DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2pyna__d2p4jd___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d2pyoa__d5fuga___1	Metazoa	Metazoa	Arthropoda	Chordata	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; lipopolysaccharide binding [GO:0001530]; protein heterodimerization activity [GO:0046982]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; nucleosome assembly [GO:0006334]; protein ubiquitination [GO:0016567]	chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; nucleosome assembly [GO:0006334]; protein ubiquitination [GO:0016567]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; lipopolysaccharide binding [GO:0001530]; protein heterodimerization activity [GO:0046982]
d2pyoc__d5gt0d___1	Metazoa	Metazoa	Arthropoda	Chordata	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2pyoe__d1kx4h___1	Metazoa	Metazoa	Arthropoda	Chordata	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]		chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2pypa__d2pr5b___1			Proteobacteria	Firmicutes	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	photoreceptor activity [GO:0009881]; protein-chromophore linkage [GO:0018298]; response to stimulus [GO:0050896]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	protein-chromophore linkage [GO:0018298]; response to stimulus [GO:0050896]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	photoreceptor activity [GO:0009881]
d2pz0b__d1o1za1__1			Firmicutes	Thermotogae	metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081]; lipid metabolic process [GO:0006629]	phosphoric diester hydrolase activity [GO:0008081]; lipid metabolic process [GO:0006629]	lipid metabolic process [GO:0006629]	lipid metabolic process [GO:0006629]			metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081]	phosphoric diester hydrolase activity [GO:0008081]
d2pz4a2_d1d2ob1__1				Firmicutes		extracellular region [GO:0005576]; peptidoglycan-based cell wall [GO:0009274]; collagen binding [GO:0005518]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		extracellular region [GO:0005576]; peptidoglycan-based cell wall [GO:0009274]		collagen binding [GO:0005518]
d2pzaa1_d1j20c1__1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]; asexual sporulation [GO:0030436]; NAD biosynthetic process [GO:0009435]; NADH metabolic process [GO:0006734]	cytoplasm [GO:0005737]; argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]	asexual sporulation [GO:0030436]; NAD biosynthetic process [GO:0009435]; NADH metabolic process [GO:0006734]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutaminase activity [GO:0004359]; metal ion binding [GO:0046872]; NAD+ synthase (glutamine-hydrolyzing) activity [GO:0003952]; NAD+ synthase activity [GO:0008795]	argininosuccinate synthase activity [GO:0004055]; ATP binding [GO:0005524]
d2pzfb__d1q1eb2__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell surface [GO:0009986]; chloride channel complex [GO:0034707]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; Golgi-associated vesicle membrane [GO:0030660]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; bicarbonate transmembrane transporter activity [GO:0015106]; chaperone binding [GO:0051087]; chloride channel activity [GO:0005254]; chloride channel inhibitor activity [GO:0019869]; chloride channel regulator activity [GO:0017081]; chloride transmembrane transporter activity [GO:0015108]; enzyme binding [GO:0019899]; intracellularly ATP-gated chloride channel activity [GO:0005260]; isomerase activity [GO:0016853]; PDZ domain binding [GO:0030165]; Sec61 translocon complex binding [GO:0106138]; bicarbonate transport [GO:0015701]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; chloride transmembrane transport [GO:1902476]; cholesterol biosynthetic process [GO:0006695]; cholesterol transport [GO:0030301]; intracellular pH elevation [GO:0051454]; membrane hyperpolarization [GO:0060081]; membrane organization [GO:0061024]; multicellular organismal water homeostasis [GO:0050891]; positive regulation of cyclic nucleotide-gated ion channel activity [GO:1902161]; positive regulation of exocytosis [GO:0045921]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of voltage-gated chloride channel activity [GO:1902943]; protein deubiquitination [GO:0016579]; response to endoplasmic reticulum stress [GO:0034976]; sperm capacitation [GO:0048240]; transepithelial water transport [GO:0035377]; transmembrane transport [GO:0055085]; vesicle docking involved in exocytosis [GO:0006904]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]; activating transcription factor binding [GO:0033613]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	bicarbonate transport [GO:0015701]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; chloride transmembrane transport [GO:1902476]; cholesterol biosynthetic process [GO:0006695]; cholesterol transport [GO:0030301]; intracellular pH elevation [GO:0051454]; membrane hyperpolarization [GO:0060081]; membrane organization [GO:0061024]; multicellular organismal water homeostasis [GO:0050891]; positive regulation of cyclic nucleotide-gated ion channel activity [GO:1902161]; positive regulation of exocytosis [GO:0045921]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of voltage-gated chloride channel activity [GO:1902943]; protein deubiquitination [GO:0016579]; response to endoplasmic reticulum stress [GO:0034976]; sperm capacitation [GO:0048240]; transepithelial water transport [GO:0035377]; transmembrane transport [GO:0055085]; vesicle docking involved in exocytosis [GO:0006904]	maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell surface [GO:0009986]; chloride channel complex [GO:0034707]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; Golgi-associated vesicle membrane [GO:0030660]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; maltose transport complex [GO:1990060]; membrane [GO:0016020]	ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; bicarbonate transmembrane transporter activity [GO:0015106]; chaperone binding [GO:0051087]; chloride channel activity [GO:0005254]; chloride channel inhibitor activity [GO:0019869]; chloride channel regulator activity [GO:0017081]; chloride transmembrane transporter activity [GO:0015108]; enzyme binding [GO:0019899]; intracellularly ATP-gated chloride channel activity [GO:0005260]; isomerase activity [GO:0016853]; PDZ domain binding [GO:0030165]; Sec61 translocon complex binding [GO:0106138]	activating transcription factor binding [GO:0033613]; ATPase activity [GO:0016887]; ATPase-coupled maltose transmembrane transporter activity [GO:0015423]; ATP binding [GO:0005524]
d2pzhc1_d3az9x___1			Proteobacteria	Apicomplexa	acyl-CoA hydrolase activity [GO:0047617]; lipid metabolic process [GO:0006629]	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	lipid metabolic process [GO:0006629]	fatty acid biosynthetic process [GO:0006633]			acyl-CoA hydrolase activity [GO:0047617]	hydro-lyase activity [GO:0016836]
d2pzhd1_d2glmb___1			Proteobacteria	Proteobacteria	acyl-CoA hydrolase activity [GO:0047617]; lipid metabolic process [GO:0006629]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	lipid metabolic process [GO:0006629]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	acyl-CoA hydrolase activity [GO:0047617]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d2pzhd1_d2xemd1__1			Proteobacteria	Actinobacteria	acyl-CoA hydrolase activity [GO:0047617]; lipid metabolic process [GO:0006629]		lipid metabolic process [GO:0006629]				acyl-CoA hydrolase activity [GO:0047617]	
d2pzla1_d4ixwa___1			Proteobacteria	Proteobacteria	coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]; transferase activity [GO:0016740]; glutamine metabolic process [GO:0006541]		glutamine metabolic process [GO:0006541]				coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]; transferase activity [GO:0016740]	
d2pzma1_d4rzic___1			Proteobacteria	Cyanobacteria	coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]; transferase activity [GO:0016740]; glutamine metabolic process [GO:0006541]	acetoacetyl-CoA reductase activity [GO:0018454]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	glutamine metabolic process [GO:0006541]	fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]; poly-hydroxybutyrate biosynthetic process [GO:0042619]			coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]; transferase activity [GO:0016740]	acetoacetyl-CoA reductase activity [GO:0018454]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d2q08b__d1j5sa1__1			Firmicutes	Thermotogae	metal ion binding [GO:0046872]	glucuronate isomerase activity [GO:0008880]; glucuronate catabolic process [GO:0006064]		glucuronate catabolic process [GO:0006064]			metal ion binding [GO:0046872]	glucuronate isomerase activity [GO:0008880]
d2q08g__d4igmf___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminocarboxymuconate-semialdehyde decarboxylase activity [GO:0001760]; hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]; negative regulation of quinolinate biosynthetic process [GO:1904985]; picolinic acid biosynthetic process [GO:1905004]; regulation of 'de novo' NAD biosynthetic process from tryptophan [GO:1905012]; tryptophan catabolic process [GO:0006569]		negative regulation of quinolinate biosynthetic process [GO:1904985]; picolinic acid biosynthetic process [GO:1905004]; regulation of 'de novo' NAD biosynthetic process from tryptophan [GO:1905012]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	metal ion binding [GO:0046872]	aminocarboxymuconate-semialdehyde decarboxylase activity [GO:0001760]; hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]
d2q08i__d4epka___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2q08k__d4qtga___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2q0aa__d3rdia1__1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; molecular adaptor activity [GO:0060090]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; molecular adaptor activity [GO:0060090]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d2q0ha__d4cr2m2__1		Fungi	Firmicutes	Ascomycota	ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATP binding [GO:0005524]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2q0mx__d182la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2q0mx__d1nmma___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d2q0ra2_d3wxja1__1	Metazoa		Chordata		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d2q11b__d1hsia___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2q15a__d3em4v___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2q17b__d1wmyb___1		Metazoa	Actinobacteria	Echinodermata	endoplasmic reticulum [GO:0005783]; calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]; post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]	metal ion binding [GO:0046872]	post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]		endoplasmic reticulum [GO:0005783]		calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]	metal ion binding [GO:0046872]
d2q17c__d3vlga___1		Metazoa	Actinobacteria	Chordata	endoplasmic reticulum [GO:0005783]; calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]; post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]	blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	endoplasmic reticulum [GO:0005783]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d2q17e__d1fifa1__1		Metazoa	Actinobacteria	Chordata	endoplasmic reticulum [GO:0005783]; calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]; post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	endoplasmic reticulum [GO:0005783]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d2q17e__d4wcoa___1		Metazoa	Actinobacteria	Chordata	endoplasmic reticulum [GO:0005783]; calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]; post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; regulation of immune response [GO:0050776]	post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]	cell surface receptor signaling pathway [GO:0007166]; regulation of immune response [GO:0050776]	endoplasmic reticulum [GO:0005783]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]	carbohydrate binding [GO:0030246]; transmembrane signaling receptor activity [GO:0004888]
d2q1ea__d1a0ql1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2q1eb__d3bqua2__1	Metazoa	Metazoa	Chordata	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2q1eb__d3zhdb1__1	Metazoa	Metazoa	Chordata	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2q1ec__d1a4jb1__1	Metazoa	Metazoa	Chordata	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2q1ec__d1ow0c2__1	Metazoa	Metazoa	Chordata	Chordata		extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]		extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]
d2q1ma1_d4rsuh___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor superfamily binding [GO:0032813]; adaptive immune response [GO:0002250]; cell-cell signaling [GO:0007267]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell adhesion [GO:0045785]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of T cell proliferation [GO:0042129]; signal transduction [GO:0007165]; T cell proliferation involved in immune response [GO:0002309]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine binding [GO:0019955]; tumor necrosis factor-activated receptor activity [GO:0005031]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of adaptive immune memory response [GO:1905675]; negative regulation of alpha-beta T cell proliferation [GO:0046642]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell migration [GO:2000406]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	adaptive immune response [GO:0002250]; cell-cell signaling [GO:0007267]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell adhesion [GO:0045785]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of T cell proliferation [GO:0042129]; signal transduction [GO:0007165]; T cell proliferation involved in immune response [GO:0002309]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of adaptive immune memory response [GO:1905675]; negative regulation of alpha-beta T cell proliferation [GO:0046642]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell migration [GO:2000406]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor superfamily binding [GO:0032813]	cytokine binding [GO:0019955]; tumor necrosis factor-activated receptor activity [GO:0005031]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2q1na2_d3bexa1__1	Metazoa		Chordata	Thermotogae	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	coenzyme A biosynthetic process [GO:0015937]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cytoplasm [GO:0005737]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d2q1wa__d1gege___1			Proteobacteria	Proteobacteria	coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]; transferase activity [GO:0016740]; glutamine metabolic process [GO:0006541]	diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; acetoin catabolic process [GO:0045150]	glutamine metabolic process [GO:0006541]	acetoin catabolic process [GO:0045150]			coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]; transferase activity [GO:0016740]	diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]
d2q20a__d1om3m2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; identical protein binding [GO:0042802]	
d2q2cb__d1p1ua___1		Metazoa	Firmicutes	Chordata	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	membrane [GO:0016020]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ligand-gated ion channel activity [GO:0015276]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2q2cc__d1tt1b___1		Metazoa	Firmicutes	Chordata	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]		behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	membrane [GO:0016020]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	ligand-gated ion channel activity [GO:0015276]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d2q2cd__d3cr9a2__1		Metazoa	Firmicutes	Chordata	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]		antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	membrane [GO:0016020]	extracellular space [GO:0005615]; specific granule [GO:0042581]	ligand-gated ion channel activity [GO:0015276]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d2q2ha__d4h02d1__1			Proteobacteria	Apicomplexa	tRNA binding [GO:0000049]	cytosol [GO:0005829]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; tRNA binding [GO:0000049]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; lysyl-tRNA aminoacylation [GO:0006430]		diadenosine tetraphosphate biosynthetic process [GO:0015966]; lysyl-tRNA aminoacylation [GO:0006430]		cytosol [GO:0005829]	tRNA binding [GO:0000049]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; tRNA binding [GO:0000049]
d2q2lb__d2aqsb___1	Viridiplantae		Streptophyta	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]		periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]
d2q2qd__d2fm3b3__1			Proteobacteria		3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]						3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	
d2q2ua2_d1taec___1				Firmicutes	ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]	DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]	DNA repair [GO:0006281]; DNA replication [GO:0006260]			ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]	DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]
d2q2ub1_d1v9pb2__1				Deinococcus-Thermus	ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]	DNA repair [GO:0006281]; DNA replication [GO:0006260]			ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]
d2q31a2_d2qwma1__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d2q32a__d1n45a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d2q39b__d4uu2b___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	carboxy-lyase activity [GO:0016831]			extracellular region [GO:0005576]		identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	carboxy-lyase activity [GO:0016831]
d2q3aa__d1fvcb___1												
d2q3aa__d4l29g2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2q3gb1_d3shub1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell-cell adherens junction [GO:0005913]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; ruffle [GO:0001726]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; actin cytoskeleton organization [GO:0030036]; axon guidance [GO:0007411]; heart development [GO:0007507]; muscle structure development [GO:0061061]; ossification [GO:0001503]; positive regulation of osteoblast differentiation [GO:0045669]; receptor-mediated endocytosis [GO:0006898]	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell projection [GO:0042995]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	actin cytoskeleton organization [GO:0030036]; axon guidance [GO:0007411]; heart development [GO:0007507]; muscle structure development [GO:0061061]; ossification [GO:0001503]; positive regulation of osteoblast differentiation [GO:0045669]; receptor-mediated endocytosis [GO:0006898]	adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of cell migration [GO:0030335]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	actin cytoskeleton [GO:0015629]; cell-cell adherens junction [GO:0005913]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; ruffle [GO:0001726]; stress fiber [GO:0001725]; Z disc [GO:0030018]	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]	actin binding [GO:0003779]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]	cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]
d2q3za1_d2bq9a2__1	Metazoa		Chordata		cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]		apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]		cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	
d2q3za2_d3ly6b4__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d2q49b2_d1ywgq2__1	Viridiplantae		Streptophyta	Apicomplexa	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; nucleolus [GO:0005730]; copper ion binding [GO:0005507]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]; response to cadmium ion [GO:0046686]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	arginine biosynthetic process [GO:0006526]; response to cadmium ion [GO:0046686]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; nucleolus [GO:0005730]		copper ion binding [GO:0005507]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2q49c2_d2b4rp2__1	Viridiplantae		Streptophyta	Apicomplexa	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; nucleolus [GO:0005730]; copper ion binding [GO:0005507]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]; response to cadmium ion [GO:0046686]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	arginine biosynthetic process [GO:0006526]; response to cadmium ion [GO:0046686]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; nucleolus [GO:0005730]		copper ion binding [GO:0005507]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2q49c2_d3qvsa2__1	Viridiplantae		Streptophyta	Euryarchaeota	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; nucleolus [GO:0005730]; copper ion binding [GO:0005507]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]; response to cadmium ion [GO:0046686]	integral component of membrane [GO:0016021]; inositol-3-phosphate synthase activity [GO:0004512]; nucleotide binding [GO:0000166]; inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	arginine biosynthetic process [GO:0006526]; response to cadmium ion [GO:0046686]	inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; nucleolus [GO:0005730]	integral component of membrane [GO:0016021]	copper ion binding [GO:0005507]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]	inositol-3-phosphate synthase activity [GO:0004512]; nucleotide binding [GO:0000166]
d2q4gw__d1k5df___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	RNA phosphodiester bond hydrolysis [GO:0090501]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	extracellular exosome [GO:0070062]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2q4ja1_d1khre___1	Viridiplantae		Streptophyta	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; pollen tube [GO:0090406]; UTP:glucose-1-phosphate uridylyltransferase activity [GO:0003983]; callose deposition in cell wall [GO:0052543]; cellular response to phosphate starvation [GO:0016036]; glycogen metabolic process [GO:0005977]; pollen development [GO:0009555]; sucrose metabolic process [GO:0005985]; UDP-glucose metabolic process [GO:0006011]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	callose deposition in cell wall [GO:0052543]; cellular response to phosphate starvation [GO:0016036]; glycogen metabolic process [GO:0005977]; pollen development [GO:0009555]; sucrose metabolic process [GO:0005985]; UDP-glucose metabolic process [GO:0006011]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; pollen tube [GO:0090406]		UTP:glucose-1-phosphate uridylyltransferase activity [GO:0003983]	transferase activity, transferring acyl groups [GO:0016746]
d2q4lb2_d3bl9a1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]; cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]	exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]
d2q54a__d3d1ya___1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2q58a__d1v4ka___1			Apicomplexa	Thermotogae	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	transferase activity [GO:0016740]; isoprenoid biosynthetic process [GO:0008299]	farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	isoprenoid biosynthetic process [GO:0008299]			dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]	transferase activity [GO:0016740]
d2q5bb__d1a65a2__1		Fungi	Cyanobacteria	Basidiomycota	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]			thylakoid membrane [GO:0042651]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2q5bc__d2ih9b3__1		Fungi	Cyanobacteria	Ascomycota	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	thylakoid membrane [GO:0042651]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2q5ea__d1cqzb1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]	cytosol [GO:0005829]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]	IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]	cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]	nucleoplasm [GO:0005654]	cytosol [GO:0005829]; peroxisome [GO:0005777]	metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2q5we1_d4ap8c___1		Metazoa	Firmicutes	Chordata	nucleotide binding [GO:0000166]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytosol [GO:0005829]; molybdopterin synthase complex [GO:0019008]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; molybdopterin synthase activity [GO:0030366]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor biosynthetic process [GO:0032324]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]		cytosol [GO:0005829]; molybdopterin synthase complex [GO:0019008]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	nucleotide binding [GO:0000166]	molybdopterin synthase activity [GO:0030366]
d2q5zb__d2oiga1__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	cytosol [GO:0005829]; dCTP diphosphatase activity [GO:0047840]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; pyrimidine deoxyribonucleotide binding [GO:0032556]; pyrophosphatase activity [GO:0016462]; dCTP catabolic process [GO:0006253]; DNA protection [GO:0042262]; nucleoside triphosphate catabolic process [GO:0009143]		dCTP catabolic process [GO:0006253]; DNA protection [GO:0042262]; nucleoside triphosphate catabolic process [GO:0009143]		cytosol [GO:0005829]	metal ion binding [GO:0046872]	dCTP diphosphatase activity [GO:0047840]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; pyrimidine deoxyribonucleotide binding [GO:0032556]; pyrophosphatase activity [GO:0016462]
d2q62b__d3f90h___1			Proteobacteria	Proteobacteria	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]				FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2q62e__d1kboa___1		Metazoa	Proteobacteria	Chordata	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d2q62g__d2v5ub___1			Proteobacteria	Cyanobacteria	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]		cell [GO:0005623]	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2q62h__d1czoa___1			Proteobacteria	Cyanobacteria	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]				FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2q62h__d2fzva1__1			Proteobacteria	Proteobacteria	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]	azobenzene reductase activity [GO:0050446]; FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]			FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]	azobenzene reductase activity [GO:0050446]; FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]
d2q63a__d1psoe___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular exosome [GO:0070062]; multivesicular body lumen [GO:0097486]; aspartic-type endopeptidase activity [GO:0004190]; cellular protein metabolic process [GO:0044267]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cellular protein metabolic process [GO:0044267]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular exosome [GO:0070062]; multivesicular body lumen [GO:0097486]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2q63a__d2cenb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2q63b__d1a8ka___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2q63b__d5v8va___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d2q6dc__d2uwla___1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	induction by virus of host autophagy [GO:0039520]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d2q6ea__d4qtgb___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2q6ga__d2gkve___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]		cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	serine-type endopeptidase inhibitor activity [GO:0004867]
d2q6gb__d2wv4a___1					cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2q6na1_d2pg5d___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	endoplasmic reticulum membrane [GO:0005789]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d2q6nc1_d4zf8a___1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum membrane [GO:0005789]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]			endoplasmic reticulum membrane [GO:0005789]	cytoplasm [GO:0005737]	aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d2q6nd1_d2pg5a___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	endoplasmic reticulum membrane [GO:0005789]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d2q6ne1_d4ejgf1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	endoplasmic reticulum membrane [GO:0005789]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d2q6ng1_d2zqja___1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum membrane [GO:0005789]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]			endoplasmic reticulum membrane [GO:0005789]		aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2q6oa2_d2cbxc1__1			Actinobacteria	Actinobacteria	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]	adenosyl-fluoride synthase activity [GO:0033846]					transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]	adenosyl-fluoride synthase activity [GO:0033846]
d2q6ob2_d2cbxb1__1			Actinobacteria	Actinobacteria	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]	adenosyl-fluoride synthase activity [GO:0033846]					transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]	adenosyl-fluoride synthase activity [GO:0033846]
d2q71a__d3gw0a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uroporphyrinogen decarboxylase activity [GO:0004853]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uroporphyrinogen decarboxylase activity [GO:0004853]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	uroporphyrinogen decarboxylase activity [GO:0004853]	uroporphyrinogen decarboxylase activity [GO:0004853]
d2q73c__d3c90x___1			Proteobacteria	Actinobacteria	metal ion binding [GO:0046872]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosyl-ATP diphosphatase activity [GO:0004636]; histidine biosynthetic process [GO:0000105]; response to host iron concentration [GO:0075139]		histidine biosynthetic process [GO:0000105]; response to host iron concentration [GO:0075139]		cell wall [GO:0005618]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosyl-ATP diphosphatase activity [GO:0004636]
d2q76c2_d3vxtd2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2q7yc2_d3m1bc1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2q7yd__d3ma9l2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2q81a1_d1qdwe___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; core promoter binding [GO:0001047]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; ectoderm development [GO:0007398]; gastrulation with mouth forming second [GO:0001702]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of transcription by RNA polymerase II [GO:0045944]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	ectoderm development [GO:0007398]; gastrulation with mouth forming second [GO:0001702]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of transcription by RNA polymerase II [GO:0045944]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	core promoter binding [GO:0001047]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]
d2q81a1_d5gita___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; core promoter binding [GO:0001047]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; ectoderm development [GO:0007398]; gastrulation with mouth forming second [GO:0001702]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of transcription by RNA polymerase II [GO:0045944]	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]; cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	ectoderm development [GO:0007398]; gastrulation with mouth forming second [GO:0001702]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of transcription by RNA polymerase II [GO:0045944]	cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]	core promoter binding [GO:0001047]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]	disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]
d2q85a1_d1ahub2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; UDP-N-acetylmuramate dehydrogenase activity [GO:0008762]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	methanol metabolic process [GO:0015945]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	peroxisome [GO:0005777]	FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; UDP-N-acetylmuramate dehydrogenase activity [GO:0008762]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d2q86b1_d5te7l1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d2q86c1_d2dtgc2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d2q86d1_d3sknd2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d2q86d1_d5d7ke1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d2q86d2_d1kcul1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2q86d2_d4d9lo2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d2q87c1_d1i1ad1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; phosphatidylethanolamine binding [GO:0008429]; phosphatidylserine binding [GO:0001786]; signaling receptor activity [GO:0038023]; cell adhesion [GO:0007155]; negative regulation of activation of Janus kinase activity [GO:1902569]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of eosinophil activation [GO:1902567]; negative regulation of eosinophil migration [GO:2000417]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mast cell activation involved in immune response [GO:0033007]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034125]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of NK T cell activation [GO:0051134]; negative regulation of phagocytosis, engulfment [GO:0060101]; neutrophil degranulation [GO:0043312]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; regulation of immune response [GO:0050776]; regulation of T cell receptor signaling pathway [GO:0050856]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell adhesion [GO:0007155]; negative regulation of activation of Janus kinase activity [GO:1902569]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of eosinophil activation [GO:1902567]; negative regulation of eosinophil migration [GO:2000417]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mast cell activation involved in immune response [GO:0033007]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034125]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of NK T cell activation [GO:0051134]; negative regulation of phagocytosis, engulfment [GO:0060101]; neutrophil degranulation [GO:0043312]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; regulation of immune response [GO:0050776]; regulation of T cell receptor signaling pathway [GO:0050856]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	phosphatidylethanolamine binding [GO:0008429]; phosphatidylserine binding [GO:0001786]; signaling receptor activity [GO:0038023]	
d2q89a1_d1y3qa___1			Proteobacteria	Proteobacteria	ectoine binding [GO:0033294]; ectoine transport [GO:0051470]	metal ion binding [GO:0046872]	ectoine transport [GO:0051470]				ectoine binding [GO:0033294]	metal ion binding [GO:0046872]
d2q8al2_d3cdfd___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d2q8ib__d1onlb___1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; identical protein binding [GO:0042802]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; pyruvate metabolic process [GO:0006090]; sleep [GO:0030431]; tricarboxylic acid cycle [GO:0006099]	glycine cleavage complex [GO:0005960]; glycine decarboxylation via glycine cleavage system [GO:0019464]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; pyruvate metabolic process [GO:0006090]; sleep [GO:0030431]; tricarboxylic acid cycle [GO:0006099]	glycine decarboxylation via glycine cleavage system [GO:0019464]	mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254]	glycine cleavage complex [GO:0005960]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; identical protein binding [GO:0042802]	
d2q8ta__d1zxtb1__1	Metazoa		Chordata		cell [GO:0005623]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	extracellular region [GO:0005576]; chemokine activity [GO:0008009]; immune response [GO:0006955]	cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	immune response [GO:0006955]	cell [GO:0005623]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]	chemokine activity [GO:0008009]
d2q8tc__d1zxtd1__1	Metazoa		Chordata		cell [GO:0005623]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	extracellular region [GO:0005576]; chemokine activity [GO:0008009]; immune response [GO:0006955]	cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	immune response [GO:0006955]	cell [GO:0005623]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]	chemokine activity [GO:0008009]
d2q8wa__d3hisb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2q8xa__d1us3a2__1			Firmicutes	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cell outer membrane [GO:0009279]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]		cell outer membrane [GO:0009279]	endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d2q8xb__d1ud4a2__1			Firmicutes	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2q8xb__d1v6xa2__1			Firmicutes	Actinobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d2q8za2_d3wk3a___1			Apicomplexa	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2q92a__d4fo8d___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]
d2q95a__d1m35e2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	protein initiator methionine removal [GO:0070084]		cytosol [GO:0005829]	cytosol [GO:0005829]	ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]	aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]
d2q96a__d3mr1a1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]
d2q9eb__d130la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2q9eb__d1i1za___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2q9ha1_d3ekmf2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]	diaminopimelate epimerase activity [GO:0008837]	diaminopimelate epimerase activity [GO:0008837]
d2q9ha1_d5ha4a1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	diaminopimelate epimerase activity [GO:0008837]	diaminopimelate epimerase activity [GO:0008837]
d2q9oa2_d3ag4b2__1	Fungi	Metazoa	Ascomycota	Chordata	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	ATP synthesis coupled electron transport [GO:0042773]	extraorganismal space [GO:0043245]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2q9ob2_d2xwzf2__1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	nitrogen compound metabolic process [GO:0006807]	extraorganismal space [GO:0043245]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2q9qa1_d2q9qc___1	Metazoa	Metazoa	Chordata	Chordata	GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; replication fork protection complex [GO:0031298]; DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]	GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; replication fork protection complex [GO:0031298]; DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]	DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]	DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]	GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; replication fork protection complex [GO:0031298]	GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; replication fork protection complex [GO:0031298]		
d2q9qh1_d2q9qg___1	Metazoa	Metazoa	Chordata	Chordata	GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; replication fork protection complex [GO:0031298]; DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]	GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; replication fork protection complex [GO:0031298]; DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]	DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]	DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]	GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; replication fork protection complex [GO:0031298]	GINS complex [GO:0000811]; nucleoplasm [GO:0005654]; replication fork protection complex [GO:0031298]		
d2q9sa__d1obqa___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	extracellular space [GO:0005615]; pigment binding [GO:0031409]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	extracellular space [GO:0005615]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	pigment binding [GO:0031409]
d2q9sa__d1opab___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol metabolic process [GO:0042572]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	retinal binding [GO:0016918]; retinol binding [GO:0019841]
d2q9ta1_d3zkla___1			Proteobacteria		ATP-binding cassette (ABC) transporter complex [GO:0043190]; phosphate ion binding [GO:0042301]; phosphate ion transmembrane transport [GO:0035435]		phosphate ion transmembrane transport [GO:0035435]		ATP-binding cassette (ABC) transporter complex [GO:0043190]		phosphate ion binding [GO:0042301]	
d2q9ua2_d3nhrb___1		Metazoa		Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d2q9ub1_d2az4a1__1				Firmicutes	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2q9va1_d1pdra___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alpha-actinin binding [GO:0051393]; ATP binding [GO:0005524]; molecular adaptor activity [GO:0060090]; protein C-terminus binding [GO:0008022]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; positive regulation of cell-cell adhesion [GO:0022409]; protein-containing complex assembly [GO:0065003]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]; cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; positive regulation of cell-cell adhesion [GO:0022409]; protein-containing complex assembly [GO:0065003]; signal transduction [GO:0007165]	actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]	alpha-actinin binding [GO:0051393]; ATP binding [GO:0005524]; molecular adaptor activity [GO:0060090]; protein C-terminus binding [GO:0008022]	cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]
d2qa0a__d3kiel___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d2qa4s1_d1xbpr1__1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	cytosolic large ribosomal subunit [GO:0022625]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2qa9e__d1danh___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]		animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d2qaaa__d1ssxa___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d2qadb1_d3ta3d1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2qadd2_d3d6ga2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2qadd2_d5kvdl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2qadf1_d2z93d1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2qadf2_d5f97e1__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2qadh2_d5ceya2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2qafa2_d3nqaa___1			Apicomplexa	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2qaka__d5p4aa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2qalf1_d1j5ef___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qamc1_d1q82c1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qamf1_d2ogkb___1				Euryarchaeota								
d2qamk1_d1qvfj___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qaml1_d2zjpi1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2qanb1_d2j00b1__1												
d2qani1_d1xxea2__1				Aquificae		metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]		lipid A biosynthetic process [GO:0009245]				metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d2qanj1_d1i97j___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qanq1_d3hfzb2__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]		phenylalanyl-tRNA aminoacylation [GO:0006432]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]
d2qaod1_d2hgqe1__1												
d2qaog1_d2qoxg2__1												
d2qaoo1_d4af1a2__1				Euryarchaeota		cytoplasm [GO:0005737]; translation release factor activity, codon specific [GO:0016149]				cytoplasm [GO:0005737]		translation release factor activity, codon specific [GO:0016149]
d2qaos1_d1vqnr1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qaot1_d2rdot1__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		ribosomal large subunit binding [GO:0043023]
d2qapa__d1fq0b___1				Proteobacteria	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	glycolytic process [GO:0006096]	metabolic process [GO:0008152]		cytosol [GO:0005829]; membrane [GO:0016020]	fructose-bisphosphate aldolase activity [GO:0004332]	(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]
d2qapb__d2qjia___1				Euryarchaeota	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; aromatic amino acid family biosynthetic process [GO:0009073]	glycolytic process [GO:0006096]	aromatic amino acid family biosynthetic process [GO:0009073]			fructose-bisphosphate aldolase activity [GO:0004332]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]
d2qapd__d3r8rr___1				Firmicutes	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d2qare__d1pk3b___1		Metazoa		Arthropoda	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	nucleus [GO:0005634]; polytene chromosome [GO:0005700]; PRC1 complex [GO:0035102]; identical protein binding [GO:0042802]; PRC1 complex binding [GO:0140259]; zinc ion binding [GO:0008270]; axonogenesis [GO:0007409]; chromatin organization [GO:0006325]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; ventral cord development [GO:0007419]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	axonogenesis [GO:0007409]; chromatin organization [GO:0006325]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; ventral cord development [GO:0007419]	host cell cytoplasm [GO:0030430]	nucleus [GO:0005634]; polytene chromosome [GO:0005700]; PRC1 complex [GO:0035102]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; PRC1 complex binding [GO:0140259]; zinc ion binding [GO:0008270]
d2qarf__d4c3wa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2qaza__d1ox9d___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; ribosome [GO:0005840]; ATPase binding [GO:0051117]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; positive regulation of ATPase activity [GO:0032781]; positive regulation of protein catabolic process [GO:0045732]		positive regulation of ATPase activity [GO:0032781]; positive regulation of protein catabolic process [GO:0045732]		cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; ribosome [GO:0005840]	identical protein binding [GO:0042802]	ATPase binding [GO:0051117]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d2qb1a__d1x66a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription by RNA polymerase II [GO:0006357]; vitellogenesis [GO:0007296]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; animal organ morphogenesis [GO:0009887]; blood circulation [GO:0008015]; cell differentiation [GO:0030154]; hemostasis [GO:0007599]; megakaryocyte development [GO:0035855]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]	cell differentiation [GO:0030154]; hematopoietic stem cell proliferation [GO:0071425]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription by RNA polymerase II [GO:0006357]; vitellogenesis [GO:0007296]	animal organ morphogenesis [GO:0009887]; blood circulation [GO:0008015]; cell differentiation [GO:0030154]; hemostasis [GO:0007599]; megakaryocyte development [GO:0035855]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein domain specific binding [GO:0019904]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d2qb9i1_d3lnua2__1				Proteobacteria		chromosome [GO:0005694]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; chromosome segregation [GO:0007059]; DNA topological change [GO:0006265]		chromosome segregation [GO:0007059]; DNA topological change [GO:0006265]		chromosome [GO:0005694]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]
d2qb9s1_d2b9os1__1												
d2qbac1_d1yl3d1__1												
d2qbad1_d2npfb1__1		Fungi		Ascomycota		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]
d2qbai1_d2hgul1__1												
d2qbao1_d2b64k1__1												
d2qbbc2_d2uxcc2__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qbbd1_d2vqed1__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qbbl1_d1ntgb1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nuclear body [GO:0016604]; ATP binding [GO:0005524]; interleukin-8 receptor binding [GO:0005153]; RNA binding [GO:0003723]; tRNA binding [GO:0000049]; tyrosine-tRNA ligase activity [GO:0004831]; apoptotic process [GO:0006915]; tRNA aminoacylation for protein translation [GO:0006418]; tyrosyl-tRNA aminoacylation [GO:0006437]		apoptotic process [GO:0006915]; tRNA aminoacylation for protein translation [GO:0006418]; tyrosyl-tRNA aminoacylation [GO:0006437]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nuclear body [GO:0016604]		ATP binding [GO:0005524]; interleukin-8 receptor binding [GO:0005153]; RNA binding [GO:0003723]; tRNA binding [GO:0000049]; tyrosine-tRNA ligase activity [GO:0004831]
d2qbcd1_d1ttta1__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2qbcj1_d1vq9j1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qbck1_d1vqmk1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qbdb1_d1vi6a___1				Euryarchaeota		small ribosomal subunit [GO:0015935]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		small ribosomal subunit [GO:0015935]		structural constituent of ribosome [GO:0003735]
d2qbdi1_d4mu0a1__1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]		histidine biosynthetic process [GO:0000105]		chloroplast [GO:0009507]		imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2qbdk1_d1k8ao___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qbeq1_d2zjpn1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2qbez1_d2j28z1__1				Proteobacteria		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]		5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]
d2qbfe1_d2qb9i1__1												
d2qbfe2_d1h2im___1		Metazoa		Chordata		nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]		cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via single-strand annealing [GO:0045002]; mitotic recombination [GO:0006312]; protein homooligomerization [GO:0051260]; regulation of nucleotide-excision repair [GO:2000819]		nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]		DNA binding [GO:0003677]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]
d2qbfi1_d2po2a1__1				Euryarchaeota		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]		RNA catabolic process [GO:0006401]		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]		3'-5'-exoribonuclease activity [GO:0000175]
d2qbg61_d1zn0a1__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		ribosomal large subunit binding [GO:0043023]
d2qbgd1_d1ob2a1__1				Proteobacteria		cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		cytosol [GO:0005829]; plasma membrane [GO:0005886]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2qbgd1_d2qexb1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qbgm1_d2gyak1__1												
d2qbgn1_d1vs8n1__1												
d2qbhk1_d1kqsm___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qbhm1_d1xnqm___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qbid1_d1r5oa1__1		Fungi		Ascomycota		cytosol [GO:0005829]; translation release factor complex [GO:0018444]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; guanyl-nucleotide exchange factor activity [GO:0005085]; magnesium ion binding [GO:0000287]; protein C-terminus binding [GO:0008022]; translation release factor activity [GO:0003747]; cytoplasmic translational termination [GO:0002184]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; translation [GO:0006412]		cytoplasmic translational termination [GO:0002184]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; translation [GO:0006412]		cytosol [GO:0005829]; translation release factor complex [GO:0018444]		GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; guanyl-nucleotide exchange factor activity [GO:0005085]; magnesium ion binding [GO:0000287]; protein C-terminus binding [GO:0008022]; translation release factor activity [GO:0003747]
d2qbis1_d1k73s___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qbiz1_d2rdoz1__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		ribosomal large subunit binding [GO:0043023]
d2qbjb1_d1fjgb___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qbjd1_d1xmqd___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qbje1_d1pkpa1__1				Firmicutes		small ribosomal subunit [GO:0015935]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; response to antibiotic [GO:0046677]; translation [GO:0006412]		response to antibiotic [GO:0046677]; translation [GO:0006412]		small ribosomal subunit [GO:0015935]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qbje1_d2f1dd1__1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]		histidine biosynthetic process [GO:0000105]		chloroplast [GO:0009507]		imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2qbji1_d1y60e___1				Proteobacteria		cytoplasm [GO:0005737]; carbon-nitrogen lyase activity [GO:0016840]; carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]		carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]		cytoplasm [GO:0005737]		carbon-nitrogen lyase activity [GO:0016840]
d2qbjj1_d1i94j___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qbjq1_d1i95q___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qbkg2_d2zjre2__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2qbkt1_d1njin___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qbkz1_d2awbz1__1												
d2qboa__d4rsna1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d2qboa__d5l90a1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2qbpa__d1zcla___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cell cycle [GO:0007049]; multicellular organism development [GO:0007275]; positive regulation of cell migration [GO:0030335]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cell cycle [GO:0007049]; multicellular organism development [GO:0007275]; positive regulation of cell migration [GO:0030335]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasm [GO:0005737]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d2qbra__d5kaca___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2qbsa__d4yr8d___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	axon [GO:0030424]; basal dendrite [GO:0097441]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; JUN kinase activity [GO:0004705]; kinase activity [GO:0016301]; MAP kinase activity [GO:0004707]; protein serine/threonine kinase activity [GO:0004674]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; JUN phosphorylation [GO:0007258]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein binding [GO:0032091]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cyclase activity [GO:0031281]; positive regulation of deacetylase activity [GO:0090045]; positive regulation of gene expression [GO:0010628]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein metabolic process [GO:0051247]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of DNA replication origin binding [GO:1902595]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of gene expression [GO:0010468]; regulation of macroautophagy [GO:0016241]; regulation of protein localization [GO:0032880]; response to UV [GO:0009411]; rhythmic process [GO:0048511]; stress-activated MAPK cascade [GO:0051403]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; JUN phosphorylation [GO:0007258]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein binding [GO:0032091]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cyclase activity [GO:0031281]; positive regulation of deacetylase activity [GO:0090045]; positive regulation of gene expression [GO:0010628]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein metabolic process [GO:0051247]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of DNA replication origin binding [GO:1902595]; regulation of gene expression [GO:0010468]; regulation of macroautophagy [GO:0016241]; regulation of protein localization [GO:0032880]; response to UV [GO:0009411]; rhythmic process [GO:0048511]; stress-activated MAPK cascade [GO:0051403]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	axon [GO:0030424]; basal dendrite [GO:0097441]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; JUN kinase activity [GO:0004705]; kinase activity [GO:0016301]; MAP kinase activity [GO:0004707]; protein serine/threonine kinase activity [GO:0004674]
d2qc2a1_d1p9ud___1					cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2qcxa1_d3hoka___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; thiaminase activity [GO:0050334]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	cytosol [GO:0005829]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	thiaminase activity [GO:0050334]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d2qd1c__d1ld3a___1	Metazoa		Chordata	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	heme biosynthetic process [GO:0006783]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]
d2qd3a__d1c1ha___1	Metazoa		Chordata	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	heme biosynthetic process [GO:0006783]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]
d2qd3b__d2q2oa___1	Metazoa		Chordata	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	heme biosynthetic process [GO:0006783]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]
d2qd5b__d2xwqa1__1	Metazoa		Chordata	Euryarchaeota	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]; anaerobic cobalamin biosynthetic process [GO:0019251]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	anaerobic cobalamin biosynthetic process [GO:0019251]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]
d2qd5b__d4klca___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d2qd6a__d2ikoa___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d2qd7a__d5p0ua___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2qd7b__d2p4jc___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d2qd7b__d5tysb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2qdda2_d3mucb1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; beta-ketoadipate pathway [GO:0042952]; cellular amino acid catabolic process [GO:0009063]		beta-ketoadipate pathway [GO:0042952]; cellular amino acid catabolic process [GO:0009063]			metal ion binding [GO:0046872]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d2qdfa1_d4xgab2__1			Proteobacteria	Proteobacteria	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]		
d2qdfa2_d4xgab1__1			Proteobacteria	Proteobacteria	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]		
d2qdfa4_d2qcza2__1			Proteobacteria	Proteobacteria	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	cell adhesion [GO:0007155]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; protein insertion into membrane [GO:0051205]	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	Bam protein complex [GO:1990063]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]		
d2qdgb__d1j2wb___1				Deinococcus-Thermus	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	glycolytic process [GO:0006096]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]		cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	deoxyribose-phosphate aldolase activity [GO:0004139]
d2qdgb__d5dbth___1				Firmicutes	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	glycolytic process [GO:0006096]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]		cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	deoxyribose-phosphate aldolase activity [GO:0004139]
d2qdgd__d5f1ua___1				Proteobacteria	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycolytic process [GO:0006096]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d2qdhd__d1adob___1		Metazoa		Chordata	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]		I band [GO:0031674]; M band [GO:0031430]	fructose-bisphosphate aldolase activity [GO:0004332]	fructose-bisphosphate aldolase activity [GO:0004332]
d2qdia__d4f7fd___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]	courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]	dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]
d2qdib__d4pt1a___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	odorant binding [GO:0005549]	courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]		dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]	odorant binding [GO:0005549]
d2qdlb__d2ch4w1__1			Firmicutes	Thermotogae	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]; chemotaxis [GO:0006935]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]
d2qdlb__d2ho9a___1			Firmicutes	Proteobacteria	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]; protein domain specific binding [GO:0019904]; chemotaxis [GO:0006935]; establishment of localization in cell [GO:0051649]; positive regulation of post-translational protein modification [GO:1901875]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	chemotaxis [GO:0006935]; establishment of localization in cell [GO:0051649]; positive regulation of post-translational protein modification [GO:1901875]; signal transduction [GO:0007165]		cell [GO:0005623]; cytosol [GO:0005829]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]		protein domain specific binding [GO:0019904]
d2qdta__d4av7e1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]
d2qdyb__d3qz5b___1			Actinobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	
d2qe0b__d4ni4b___1			Firmicutes		glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]						glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	
d2qe0c__d3rhja___1		Metazoa	Firmicutes	Chordata	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]
d2qe7a3_d3a5ck4__1			Firmicutes	Deinococcus-Thermus	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2qe7d1_d3oeev1__1		Fungi	Firmicutes	Ascomycota	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2qe7f1_d2v7qc1__1		Metazoa	Firmicutes	Chordata	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2qeeg1_d4infa___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2qeej1_d3giqb2__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; N-acyl-D-glutamate deacylase activity [GO:0047421]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; N-acyl-D-glutamate deacylase activity [GO:0047421]
d2qejb1_d5grwb2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; monomeric IgA immunoglobulin complex [GO:0071748]; secretory dimeric IgA immunoglobulin complex [GO:0071752]; secretory IgA immunoglobulin complex [GO:0071751]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of respiratory burst [GO:0060267]; protein-chromophore linkage [GO:0018298]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		antibacterial humoral response [GO:0019731]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of respiratory burst [GO:0060267]; protein-chromophore linkage [GO:0018298]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; monomeric IgA immunoglobulin complex [GO:0071748]; secretory dimeric IgA immunoglobulin complex [GO:0071752]; secretory IgA immunoglobulin complex [GO:0071751]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2qejb2_d4hcra1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; monomeric IgA immunoglobulin complex [GO:0071748]; secretory dimeric IgA immunoglobulin complex [GO:0071752]; secretory IgA immunoglobulin complex [GO:0071751]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of respiratory burst [GO:0060267]; protein-chromophore linkage [GO:0018298]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; integrin binding involved in cell-matrix adhesion [GO:0098640]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	antibacterial humoral response [GO:0019731]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of respiratory burst [GO:0060267]; protein-chromophore linkage [GO:0018298]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; monomeric IgA immunoglobulin complex [GO:0071748]; secretory dimeric IgA immunoglobulin complex [GO:0071752]; secretory IgA immunoglobulin complex [GO:0071751]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	integrin binding involved in cell-matrix adhesion [GO:0098640]
d2qexb1_d3sjza2__1			Euryarchaeota	Crenarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	translation [GO:0006412]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	ribosome [GO:0005840]	cytosol [GO:0005829]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d2qexk1_d1n8rl___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qexr1_d1vsaq1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d2qf2b1_d4rija1__1	Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]		aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]	
d2qfde__d2rmja___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; cellular response to exogenous dsRNA [GO:0071360]; cytoplasmic pattern recognition receptor signaling pathway in response to virus [GO:0039528]; defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; negative regulation of type I interferon production [GO:0032480]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interferon-beta secretion [GO:0035549]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor secretion [GO:1904469]; protein deubiquitination [GO:0016579]; regulation of cell migration [GO:0030334]; regulation of type III interferon production [GO:0034344]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529]; viral process [GO:0016032]	actin cytoskeleton [GO:0015629]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; cellular response to exogenous dsRNA [GO:0071360]; cytoplasmic pattern recognition receptor signaling pathway in response to virus [GO:0039528]; defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; negative regulation of type I interferon production [GO:0032480]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interferon-beta secretion [GO:0035549]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor secretion [GO:1904469]; protein deubiquitination [GO:0016579]; regulation of cell migration [GO:0030334]; regulation of type III interferon production [GO:0034344]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529]; viral process [GO:0016032]	cellular response to exogenous dsRNA [GO:0071360]; cytoplasmic pattern recognition receptor signaling pathway in response to virus [GO:0039528]; defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; negative regulation of type I interferon production [GO:0032480]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interferon-beta secretion [GO:0035549]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor secretion [GO:1904469]; protein deubiquitination [GO:0016579]; regulation of cell migration [GO:0030334]; regulation of type III interferon production [GO:0034344]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529]; viral process [GO:0016032]	cellular response to exogenous dsRNA [GO:0071360]; cytoplasmic pattern recognition receptor signaling pathway in response to virus [GO:0039528]; defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; negative regulation of type I interferon production [GO:0032480]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interferon-beta secretion [GO:0035549]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor secretion [GO:1904469]; protein deubiquitination [GO:0016579]; regulation of cell migration [GO:0030334]; regulation of type III interferon production [GO:0034344]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529]; viral process [GO:0016032]	actin cytoskeleton [GO:0015629]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	actin cytoskeleton [GO:0015629]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	ATP binding [GO:0005524]; double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; identical protein binding [GO:0042802]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d2qfib1_d3h90a2__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadmium ion transmembrane transporter activity [GO:0015086]; cation transmembrane transporter activity [GO:0008324]; ferrous iron transmembrane transporter activity [GO:0015093]; identical protein binding [GO:0042802]; zinc efflux active transmembrane transporter activity [GO:0015341]; cadmium ion transport [GO:0015691]; cellular cadmium ion homeostasis [GO:0006876]; cellular iron ion homeostasis [GO:0006879]; cellular zinc ion homeostasis [GO:0006882]; iron ion transport [GO:0006826]; zinc ion transport [GO:0006829]	cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadmium ion transmembrane transporter activity [GO:0015086]; cation transmembrane transporter activity [GO:0008324]; ferrous iron transmembrane transporter activity [GO:0015093]; identical protein binding [GO:0042802]; zinc efflux active transmembrane transporter activity [GO:0015341]; cadmium ion transport [GO:0015691]; cellular cadmium ion homeostasis [GO:0006876]; cellular iron ion homeostasis [GO:0006879]; cellular zinc ion homeostasis [GO:0006882]; iron ion transport [GO:0006826]; zinc ion transport [GO:0006829]	cadmium ion transport [GO:0015691]; cellular cadmium ion homeostasis [GO:0006876]; cellular iron ion homeostasis [GO:0006879]; cellular zinc ion homeostasis [GO:0006882]; iron ion transport [GO:0006826]; zinc ion transport [GO:0006829]	cadmium ion transport [GO:0015691]; cellular cadmium ion homeostasis [GO:0006876]; cellular iron ion homeostasis [GO:0006879]; cellular zinc ion homeostasis [GO:0006882]; iron ion transport [GO:0006826]; zinc ion transport [GO:0006829]	cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cadmium ion transmembrane transporter activity [GO:0015086]; cation transmembrane transporter activity [GO:0008324]; ferrous iron transmembrane transporter activity [GO:0015093]; identical protein binding [GO:0042802]; zinc efflux active transmembrane transporter activity [GO:0015341]	cadmium ion transmembrane transporter activity [GO:0015086]; cation transmembrane transporter activity [GO:0008324]; ferrous iron transmembrane transporter activity [GO:0015093]; identical protein binding [GO:0042802]; zinc efflux active transmembrane transporter activity [GO:0015341]
d2qfka__d1j7yb___1	Metazoa	Metazoa	Annelida	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2qfka__d2uult___1	Metazoa		Annelida		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	
d2qfnb__d4h0mq___1	Metazoa		Annelida	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	
d2qfpa2_d3e7ba1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	extracellular region [GO:0005576]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]
d2qfrb2_d5uq6a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	extracellular region [GO:0005576]; lysosome [GO:0005764]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]		bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; lysosome [GO:0005764]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]
d2qfvb__d3ty4b___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; homoisocitrate dehydrogenase activity [GO:0047046]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; lysine biosynthetic process [GO:0009085]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	lysine biosynthetic process [GO:0009085]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	homoisocitrate dehydrogenase activity [GO:0047046]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d2qfwb__d1pb1a___1	Fungi		Ascomycota	Proteobacteria	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d2qfwc__d5hn6a___1	Fungi		Ascomycota	Euryarchaeota	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	mitochondrion [GO:0005739]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; homoisocitrate dehydrogenase activity [GO:0047046]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]; lysine biosynthetic process [GO:0009085]	glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]; lysine biosynthetic process [GO:0009085]	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	3-isopropylmalate dehydrogenase activity [GO:0003862]; homoisocitrate dehydrogenase activity [GO:0047046]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d2qfyf__d1td9f___1	Fungi		Ascomycota	Firmicutes	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	glutamate biosynthetic process [GO:0006537]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	acetyl-CoA biosynthetic process [GO:0006085]	mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	phosphate acetyltransferase activity [GO:0008959]
d2qg9c1_d4nf2b1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d2qg9d1_d3at1b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2qgba__d2igla1__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	periplasmic space [GO:0042597]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]
d2qgca__d1gkoa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d2qgcb__d1soqa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d2qgea__d2g2nc___1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	periplasmic space [GO:0042597]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]
d2qgfa1_d1raic1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2qgfb1_d3mpud1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2qgfc1_d3r7lf2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d2qgfc2_d2g7my2__1			Proteobacteria	Bacteroidetes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; cellular amino acid metabolic process [GO:0006520]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]
d2qgxb__d3hctb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; filopodium [GO:0030175]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; embryo implantation [GO:0007566]; fertilization [GO:0009566]; mating behavior [GO:0007617]; prolactin secretion [GO:0070459]; reproductive system development [GO:0061458]; suckling behavior [GO:0001967]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; UBC13-MMS2 complex [GO:0031372]; UBC13-UEV1A complex [GO:0035370]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; activation of MAPK activity [GO:0000187]; cellular protein modification process [GO:0006464]; DNA double-strand break processing [GO:0000729]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone ubiquitination [GO:0016574]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of DNA repair [GO:0045739]; positive regulation of histone modification [GO:0031058]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of DNA repair [GO:0006282]; regulation of histone ubiquitination [GO:0033182]; T cell receptor signaling pathway [GO:0050852]	embryo implantation [GO:0007566]; fertilization [GO:0009566]; mating behavior [GO:0007617]; prolactin secretion [GO:0070459]; reproductive system development [GO:0061458]; suckling behavior [GO:0001967]	activation of MAPK activity [GO:0000187]; cellular protein modification process [GO:0006464]; DNA double-strand break processing [GO:0000729]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone ubiquitination [GO:0016574]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of DNA repair [GO:0045739]; positive regulation of histone modification [GO:0031058]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of DNA repair [GO:0006282]; regulation of histone ubiquitination [GO:0033182]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; filopodium [GO:0030175]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; UBC13-MMS2 complex [GO:0031372]; UBC13-UEV1A complex [GO:0035370]; ubiquitin ligase complex [GO:0000151]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]	ATP binding [GO:0005524]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]
d2qgxc__d1y6la1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; filopodium [GO:0030175]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; embryo implantation [GO:0007566]; fertilization [GO:0009566]; mating behavior [GO:0007617]; prolactin secretion [GO:0070459]; reproductive system development [GO:0061458]; suckling behavior [GO:0001967]	ATP binding [GO:0005524]; ISG15 transferase activity [GO:0042296]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]; cellular response to DNA damage stimulus [GO:0006974]; ISG15-protein conjugation [GO:0032020]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]	embryo implantation [GO:0007566]; fertilization [GO:0009566]; mating behavior [GO:0007617]; prolactin secretion [GO:0070459]; reproductive system development [GO:0061458]; suckling behavior [GO:0001967]	cellular response to DNA damage stimulus [GO:0006974]; ISG15-protein conjugation [GO:0032020]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]	cytosol [GO:0005829]; filopodium [GO:0030175]; nucleus [GO:0005634]		ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]	ATP binding [GO:0005524]; ISG15 transferase activity [GO:0042296]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]
d2qh0a1_d1kw8b2__1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]		aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]			lyase activity [GO:0016829]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]
d2qh1a1_d3tdhc1__1		Fungi	Euryarchaeota	Ascomycota	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein kinase binding [GO:0019901]; cellular response to glucose starvation [GO:0042149]; invasive growth in response to glucose limitation [GO:0001403]; positive regulation of pseudohyphal growth [GO:2000222]; protein phosphorylation [GO:0006468]; regulation of protein complex assembly [GO:0043254]; regulation of protein kinase activity [GO:0045859]; replicative cell aging [GO:0001302]; signal transduction [GO:0007165]		cellular response to glucose starvation [GO:0042149]; invasive growth in response to glucose limitation [GO:0001403]; positive regulation of pseudohyphal growth [GO:2000222]; protein phosphorylation [GO:0006468]; regulation of protein complex assembly [GO:0043254]; regulation of protein kinase activity [GO:0045859]; replicative cell aging [GO:0001302]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	protein kinase binding [GO:0019901]
d2qhca__d2uxza___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2qhca__d4y37a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2qhea__d1a2aa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d2qhga__d1q6va___1		Metazoa		Chordata		extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]		arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]		extracellular region [GO:0005576]		calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]
d2qhge__d4p2pa___1		Metazoa		Chordata		cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]; bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]		activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]		cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]		bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]
d2qhgg__d4dcfb___1		Metazoa		Chordata		extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]		arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]		extracellular region [GO:0005576]		calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]
d2qhla__d1nbza1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2qhla__d4nqch1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2qhlb__d3hnsl2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d2qhoc__d2kjra1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; cytoplasmic microtubule organization [GO:0031122]; establishment of apical/basal cell polarity [GO:0035089]; oocyte axis specification [GO:0007309]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytoplasmic microtubule organization [GO:0031122]; establishment of apical/basal cell polarity [GO:0035089]; oocyte axis specification [GO:0007309]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	
d2qhoe__d4p7ib1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d2qhyb__d5p7ya___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2qi1a__d5p8na___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2qi1b__d5p0ta___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2qi3b__d1s65b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d2qi3b__d2rmpa___1		Fungi		Mucoromycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2qi4b__d5lwra___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2qi5a__d5ozpa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2qi5b__d5p03a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2qi6a__d1hhpa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2qi7b__d3plla___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2qidb__d2bdip___1		Metazoa		Chordata		extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]		amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]		extracellular region [GO:0005576]; secretory granule [GO:0030141]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2qifa__d2g9oa___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; copper ion transport [GO:0006825]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]; antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	copper ion transport [GO:0006825]	antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cytoplasm [GO:0005737]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	copper ion binding [GO:0005507]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]
d2qila1_d1qnue___1			Firmicutes		extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d2qilb2_d4o1nb2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; peptidase activity [GO:0008233]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	peptidase activity [GO:0008233]
d2qima__d2xrxq2__1	Viridiplantae		Streptophyta	Proteobacteria	cytosol [GO:0005829]; abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]	aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]		abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2qina__d3iekc___1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	rRNA processing [GO:0006364]	periplasmic space [GO:0042597]	cytoplasm [GO:0005737]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2qinc__d4rbsb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2qind__d3spua1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2qind__d4uama___1			Proteobacteria		periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	
d2qioc__d1r72a4__1			Firmicutes		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]				enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]	
d2qj7a__d1t1aa___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d2qj7a__d5a8bb___1			Proteobacteria	Bacillariophyta (diatoms)	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nucleotide binding [GO:0000166]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]				identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	nucleotide binding [GO:0000166]
d2qjda__d3c5sc2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2qjfb1_d5o95a1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]; methyltransferase activity [GO:0008168]; rRNA processing [GO:0006364]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	rRNA processing [GO:0006364]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	methyltransferase activity [GO:0008168]
d2qjia__d1jcjb1__1			Euryarchaeota	Proteobacteria	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; aromatic amino acid family biosynthetic process [GO:0009073]	cytosol [GO:0005829]; membrane [GO:0016020]; deoxyribose-phosphate aldolase activity [GO:0004139]; lyase activity [GO:0016829]; carbohydrate catabolic process [GO:0016052]; cellular response to DNA damage stimulus [GO:0006974]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]; nucleobase-containing small molecule interconversion [GO:0015949]	aromatic amino acid family biosynthetic process [GO:0009073]	carbohydrate catabolic process [GO:0016052]; cellular response to DNA damage stimulus [GO:0006974]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]; nucleobase-containing small molecule interconversion [GO:0015949]		cytosol [GO:0005829]; membrane [GO:0016020]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	deoxyribose-phosphate aldolase activity [GO:0004139]; lyase activity [GO:0016829]
d2qjib__d3puea___1			Euryarchaeota	Proteobacteria	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; aromatic amino acid family biosynthetic process [GO:0009073]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aromatic amino acid family biosynthetic process [GO:0009073]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d2qjif__d3mmtc1__1			Euryarchaeota	Proteobacteria	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; aromatic amino acid family biosynthetic process [GO:0009073]	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	aromatic amino acid family biosynthetic process [GO:0009073]	glycolytic process [GO:0006096]			fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	fructose-bisphosphate aldolase activity [GO:0004332]
d2qjio__d1dhpb___1			Euryarchaeota	Proteobacteria	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; aromatic amino acid family biosynthetic process [GO:0009073]	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aromatic amino acid family biosynthetic process [GO:0009073]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytosol [GO:0005829]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]
d2qjip__d4u4mb___1			Euryarchaeota	Proteobacteria	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; aromatic amino acid family biosynthetic process [GO:0009073]	cytoplasm [GO:0005737]; 2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]; aldonic acid catabolic process [GO:0046176]	aromatic amino acid family biosynthetic process [GO:0009073]	aldonic acid catabolic process [GO:0046176]		cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]
d2qjir__d4oe7a___1			Euryarchaeota	Proteobacteria	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; aromatic amino acid family biosynthetic process [GO:0009073]	cytoplasm [GO:0005737]; 2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]; aldonic acid catabolic process [GO:0046176]	aromatic amino acid family biosynthetic process [GO:0009073]	aldonic acid catabolic process [GO:0046176]		cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]
d2qjjb1_d4ihcg1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d2qjjb2_d3shhb2__1			Proteobacteria		magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]		carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]				magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	
d2qjna1_d2ptya2__1			Proteobacteria		magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	glycolytic process [GO:0006096]		ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2qjnb1_d2p88a1__1			Proteobacteria	Firmicutes	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]; peptide metabolic process [GO:0006518]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	peptide metabolic process [GO:0006518]			magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]
d2qjrb2_d1yaji1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d2qjsd__d2yntc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d2qk4a1_d4mv7a1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2qk4a3_d1kjjb1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d2qk4b1_d5c1pd1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2qkaa1_d3dc5a1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	removal of superoxide radicals [GO:0019430]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]
d2qkaa2_d1za5a2__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]
d2qkca2_d1zlzb2__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2qkcc2_d4jyya2__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2qklb__d5kq4e1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Dcp1-Dcp2 complex [GO:0098745]; mRNA cap binding complex [GO:0005845]; nucleus [GO:0005634]; P-body [GO:0000932]; m7G(5')pppN diphosphatase activator activity [GO:1990521]; RNA binding [GO:0003723]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; mRNA processing [GO:0006397]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3' [GO:0034428]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Dcp1-Dcp2 complex [GO:0098745]; mRNA cap binding complex [GO:0005845]; nucleus [GO:0005634]; P-body [GO:0000932]; m7G(5')pppN diphosphatase activator activity [GO:1990521]; RNA binding [GO:0003723]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; mRNA processing [GO:0006397]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3' [GO:0034428]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; mRNA processing [GO:0006397]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3' [GO:0034428]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; mRNA processing [GO:0006397]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3' [GO:0034428]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Dcp1-Dcp2 complex [GO:0098745]; mRNA cap binding complex [GO:0005845]; nucleus [GO:0005634]; P-body [GO:0000932]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Dcp1-Dcp2 complex [GO:0098745]; mRNA cap binding complex [GO:0005845]; nucleus [GO:0005634]; P-body [GO:0000932]	m7G(5')pppN diphosphatase activator activity [GO:1990521]; RNA binding [GO:0003723]	m7G(5')pppN diphosphatase activator activity [GO:1990521]; RNA binding [GO:0003723]
d2qkyd2_d2qxug___1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d2qlaa__d1nbba___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2qlpc__d1q5ha___1		Metazoa	Actinobacteria	Chordata	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]		extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d2qlpc__d4apzt___1			Actinobacteria	Firmicutes	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2qlsb1_d5ksjb___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2qlya2_d3gxdd2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d2qm9a2_d4xmca___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; negative regulation of coagulation [GO:0050819]; nitric oxide homeostasis [GO:0033484]; platelet aggregation [GO:0070527]; positive regulation of blood vessel diameter [GO:0097755]; response to histamine [GO:0034776]; vasodilation [GO:0042311]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	negative regulation of coagulation [GO:0050819]; nitric oxide homeostasis [GO:0033484]; platelet aggregation [GO:0070527]; positive regulation of blood vessel diameter [GO:0097755]; response to histamine [GO:0034776]; vasodilation [GO:0042311]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	extracellular region [GO:0005576]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d2qmba__d1o1pa2__1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2qmbb__d1moaa___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2qmbc__d1a0ub___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2qmda__d4k4pb___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2qmea1_d5cj2e___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; axon [GO:0030424]; cell-cell junction [GO:0005911]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; focal adhesion [GO:0005925]; intercalated disc [GO:0014704]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Z disc [GO:0030018]; ATP binding [GO:0005524]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; actin cytoskeleton reorganization [GO:0031532]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; branching morphogenesis of an epithelial tube [GO:0048754]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cerebellum development [GO:0021549]; chromatin remodeling [GO:0006338]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; exocytosis [GO:0006887]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; neuron projection morphogenesis [GO:0048812]; positive regulation of axon extension [GO:0045773]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; response to hypoxia [GO:0001666]; signal transduction by protein phosphorylation [GO:0023014]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; wound healing [GO:0042060]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	actin cytoskeleton reorganization [GO:0031532]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; branching morphogenesis of an epithelial tube [GO:0048754]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cerebellum development [GO:0021549]; chromatin remodeling [GO:0006338]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; exocytosis [GO:0006887]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; neuron projection morphogenesis [GO:0048812]; positive regulation of axon extension [GO:0045773]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; response to hypoxia [GO:0001666]; signal transduction by protein phosphorylation [GO:0023014]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; wound healing [GO:0042060]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	actin filament [GO:0005884]; axon [GO:0030424]; cell-cell junction [GO:0005911]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; focal adhesion [GO:0005925]; intercalated disc [GO:0014704]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Z disc [GO:0030018]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	ATP binding [GO:0005524]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2qmfa__d2aoha___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2qmhb__d5v9ga2__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphorelay sensor kinase activity [GO:0000155]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; carbohydrate metabolic process [GO:0005975]; regulation of carbohydrate metabolic process [GO:0006109]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	carbohydrate metabolic process [GO:0005975]; regulation of carbohydrate metabolic process [GO:0006109]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphorelay sensor kinase activity [GO:0000155]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]
d2qmja2_d1uhvc2__1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	xylan catabolic process [GO:0045493]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]		amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d2qmsa__d1cj1k___1	Metazoa	Metazoa	Chordata	Chordata	cell projection [GO:0042995]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; axon guidance [GO:0007411]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; leukocyte migration [GO:0050900]; negative regulation of translation [GO:0017148]; positive regulation of cell migration [GO:0030335]; stress granule assembly [GO:0034063]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	axon guidance [GO:0007411]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; leukocyte migration [GO:0050900]; negative regulation of translation [GO:0017148]; positive regulation of cell migration [GO:0030335]; stress granule assembly [GO:0034063]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cell projection [GO:0042995]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]
d2qmsb__d1bfia___1	Metazoa	Metazoa	Chordata	Chordata	cell projection [GO:0042995]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; axon guidance [GO:0007411]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; leukocyte migration [GO:0050900]; negative regulation of translation [GO:0017148]; positive regulation of cell migration [GO:0030335]; stress granule assembly [GO:0034063]	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]; 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; insulin-like growth factor receptor binding [GO:0005159]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]; B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; growth hormone receptor signaling pathway [GO:0060396]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]	axon guidance [GO:0007411]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; leukocyte migration [GO:0050900]; negative regulation of translation [GO:0017148]; positive regulation of cell migration [GO:0030335]; stress granule assembly [GO:0034063]	B cell differentiation [GO:0030183]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to UV [GO:0034644]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; growth hormone receptor signaling pathway [GO:0060396]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of osteoclast differentiation [GO:0045671]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import [GO:0046326]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of stress fiber assembly [GO:0051492]; response to endoplasmic reticulum stress [GO:0034976]	cell projection [GO:0042995]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]	cell [GO:0005623]; cell-cell junction [GO:0005911]; cis-Golgi network [GO:0005801]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum membrane [GO:1990578]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IA [GO:0005943]	identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]	1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatidylinositol 3-kinase binding [GO:0043548]; phosphatidylinositol 3-kinase regulator activity [GO:0035014]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; transcription factor binding [GO:0008134]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068]
d2qmua3_d4acbc4__1			Crenarchaeota	Euryarchaeota	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; selenocysteine incorporation [GO:0001514]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	selenocysteine incorporation [GO:0001514]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2qmya__d2mt9a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2qmza__d2ohie2__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d2qn0a1_d1qiad___1		Metazoa		Chordata	extracellular region [GO:0005576]; ganglioside binding [GO:0035594]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; membrane protein proteolysis [GO:0033619]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	membrane protein proteolysis [GO:0033619]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of neurotransmitter secretion [GO:0046929]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	ganglioside binding [GO:0035594]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d2qn6a1_d4j0qb2__1			Crenarchaeota	Proteobacteria	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2qnhi1_d1s03g___1				Proteobacteria		cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; regulation of mRNA stability [GO:0043488]; regulation of translation [GO:0006417]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]		regulation of mRNA stability [GO:0043488]; regulation of translation [GO:0006417]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]		cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qnhj1_d1fwka1__1				Euryarchaeota		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]		threonine biosynthetic process [GO:0009088]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]
d2qnna__d1bv7a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2qnnb__d1sgzb___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d2qnpa__d3kdda___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2qnqb__d2r3ta___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2qnxa2_d2qo1b1__1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d2qnya2_d2cdhd2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2qnyb2_d5bz4c2__1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2qnza2_d2cdhb1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2qnza2_d4wumd1__1		Viridiplantae	Actinobacteria	Streptophyta	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	naringenin-chalcone synthase activity [GO:0016210]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	naringenin-chalcone synthase activity [GO:0016210]
d2qnzb2_d4efia2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2qo0a2_d3v4nc2__1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d2qo1a1_d1hnda2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2qo1a2_d2gp6a1__1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to hypoxia [GO:0001666]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to hypoxia [GO:0001666]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2qo6a__d4zhcc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; bile acid binding [GO:0032052]; lipid binding [GO:0008289]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]		antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	bile acid binding [GO:0032052]; lipid binding [GO:0008289]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d2qoeb2_d5ih7a___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	acetylcholinesterase activity [GO:0003990]
d2qogb__d1ppaa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; envenomation resulting in induction of edema in other organism [GO:0044398]; envenomation resulting in modulation of apoptotic process in other organism [GO:0044534]; envenomation resulting in muscle damage in other organism [GO:0044521]; envenomation resulting in positive regulation of platelet aggregation in other organism [GO:0044478]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; envenomation resulting in induction of edema in other organism [GO:0044398]; envenomation resulting in modulation of apoptotic process in other organism [GO:0044534]; envenomation resulting in muscle damage in other organism [GO:0044521]; envenomation resulting in positive regulation of platelet aggregation in other organism [GO:0044478]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]
d2qoui1_d1n0vc3__1		Fungi		Ascomycota		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]		cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]
d2qouk1_d1dt9a1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; translation release factor complex [GO:0018444]; ribosome binding [GO:0043022]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; translation release factor activity [GO:0003747]; translation release factor activity, codon specific [GO:0016149]; translation termination factor activity [GO:0008079]; cytoplasmic translational termination [GO:0002184]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein methylation [GO:0006479]; regulation of translational termination [GO:0006449]		cytoplasmic translational termination [GO:0002184]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein methylation [GO:0006479]; regulation of translational termination [GO:0006449]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; translation release factor complex [GO:0018444]		ribosome binding [GO:0043022]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; translation release factor activity [GO:0003747]; translation release factor activity, codon specific [GO:0016149]; translation termination factor activity [GO:0008079]
d2qous1_d1hnzs___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qovd1_d1dg1g1__1				Proteobacteria		cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		cytosol [GO:0005829]; plasma membrane [GO:0005886]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2qove1_d1vq6c1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qovg2_d1kqse1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qovj1_d3bbxj1__1				Proteobacteria		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]		5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]
d2qowl1_d1qvca___1				Proteobacteria		cytosol [GO:0005829]; enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]		DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]		cytosol [GO:0005829]		enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]
d2qoxd1_d2rdod1__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		ribosomal large subunit binding [GO:0043023]
d2qoxe1_d2aw4e1__1												
d2qoxf1_d2ogkd___1				Euryarchaeota								
d2qoxh1_d2b9pi1__1												
d2qoyc1_d2hgrf1__1												
d2qoyc2_d1yl4f2__1												
d2qoyf1_d2ow8g1__1												
d2qoyi1_d2f1dg1__1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]		histidine biosynthetic process [GO:0000105]		chloroplast [GO:0009507]		imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2qozc1_d1vq8a1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qozi2_d3cjtb2__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; protein methyltransferase activity [GO:0008276]				cytoplasm [GO:0005737]		protein methyltransferase activity [GO:0008276]
d2qozo1_d2vqek1__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qp0c1_d1xmoc1__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qp0e1_d2hgrh1__1												
d2qp0e2_d2hgih2__1												
d2qp0f1_d2e5lf1__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2qp0i1_d1nzta4__1												
d2qp1d1_d1exma1__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2qp1q1_d2zjrn1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2qp1s1_d3ccqr1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2qp8a__d4cpwa___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2qpdb1_d1cyxa___1			Deinococcus-Thermus	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	cytochrome o ubiquinol oxidase complex [GO:0009319]; integral component of external side of plasma membrane [GO:0071575]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome bo3 ubiquinol oxidase activity [GO:0009486]; cytochrome o ubiquinol oxidase activity [GO:0008827]; cytochrome-c oxidase activity [GO:0004129]; electron transfer activity [GO:0009055]; oxidoreduction-driven active transmembrane transporter activity [GO:0015453]; proton transmembrane transporter activity [GO:0015078]; ubiquinone binding [GO:0048039]; aerobic electron transport chain [GO:0019646]; aerobic respiration [GO:0009060]; ATP synthesis coupled electron transport [GO:0042773]; electron transport coupled proton transport [GO:0015990]		aerobic electron transport chain [GO:0019646]; aerobic respiration [GO:0009060]; ATP synthesis coupled electron transport [GO:0042773]; electron transport coupled proton transport [GO:0015990]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	cytochrome o ubiquinol oxidase complex [GO:0009319]; integral component of external side of plasma membrane [GO:0071575]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; cytochrome bo3 ubiquinol oxidase activity [GO:0009486]; cytochrome-c oxidase activity [GO:0004129]; cytochrome o ubiquinol oxidase activity [GO:0008827]; electron transfer activity [GO:0009055]; oxidoreduction-driven active transmembrane transporter activity [GO:0015453]; proton transmembrane transporter activity [GO:0015078]; ubiquinone binding [GO:0048039]
d2qpdb1_d1paza___1			Deinococcus-Thermus	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2qpeb1_d3t71b3__1		Fungi	Deinococcus-Thermus	Basidiomycota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]		copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2qpfd__d4tlsb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; hormone binding [GO:0042562]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d2qpma1_d5fxea1__1	Viridiplantae		Streptophyta	Actinobacteria	extracellular space [GO:0005615]; cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	cytokinin metabolic process [GO:0009690]		extracellular space [GO:0005615]		cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d2qpub2_d4duxc3__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular space [GO:0005615]	beta-galactosidase complex [GO:0009341]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2qpuc2_d1dwam___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]	vacuole [GO:0005773]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]
d2qpya__d1xlsg___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; rough endoplasmic reticulum [GO:0005791]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA polymerase binding [GO:0070182]; estrogen receptor binding [GO:0030331]; glucocorticoid receptor binding [GO:0035259]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; PDZ domain binding [GO:0030165]; progesterone receptor binding [GO:0033142]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; protein-containing complex binding [GO:0044877]; retinoic acid receptor binding [GO:0042974]; retinoid X receptor binding [GO:0046965]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; signaling receptor binding [GO:0005102]; thyroid hormone receptor binding [GO:0046966]; thyroid hormone receptor coactivator activity [GO:0030375]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; locomotor rhythm [GO:0045475]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of female receptivity [GO:0045925]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; response to progesterone [GO:0032570]	mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]; chromatin DNA binding [GO:0031490]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; nuclear receptor activity [GO:0004879]; nuclear receptor binding [GO:0016922]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; retinoic acid binding [GO:0001972]; retinoic acid-responsive element binding [GO:0044323]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription coactivator activity [GO:0003713]; vitamin D receptor binding [GO:0042809]; zinc ion binding [GO:0008270]; anatomical structure development [GO:0048856]; bile acid and bile salt transport [GO:0015721]; camera-type eye development [GO:0043010]; cardiac muscle cell proliferation [GO:0060038]; cell differentiation [GO:0030154]; cholesterol metabolic process [GO:0008203]; embryo implantation [GO:0007566]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; modulation by virus of host morphology or physiology [GO:0019048]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ventricular cardiac muscle cell differentiation [GO:0055012]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; vitamin metabolic process [GO:0006766]	cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; locomotor rhythm [GO:0045475]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of female receptivity [GO:0045925]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; response to progesterone [GO:0032570]	anatomical structure development [GO:0048856]; bile acid and bile salt transport [GO:0015721]; camera-type eye development [GO:0043010]; cardiac muscle cell proliferation [GO:0060038]; cell differentiation [GO:0030154]; cholesterol metabolic process [GO:0008203]; embryo implantation [GO:0007566]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; modulation by virus of host morphology or physiology [GO:0019048]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ventricular cardiac muscle cell differentiation [GO:0055012]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; vitamin metabolic process [GO:0006766]	cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; rough endoplasmic reticulum [GO:0005791]	mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]	aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA polymerase binding [GO:0070182]; estrogen receptor binding [GO:0030331]; glucocorticoid receptor binding [GO:0035259]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; PDZ domain binding [GO:0030165]; progesterone receptor binding [GO:0033142]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; retinoic acid receptor binding [GO:0042974]; retinoid X receptor binding [GO:0046965]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; signaling receptor binding [GO:0005102]; thyroid hormone receptor binding [GO:0046966]; thyroid hormone receptor coactivator activity [GO:0030375]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]	chromatin DNA binding [GO:0031490]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; nuclear receptor activity [GO:0004879]; nuclear receptor binding [GO:0016922]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; retinoic acid binding [GO:0001972]; retinoic acid-responsive element binding [GO:0044323]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription coactivator activity [GO:0003713]; vitamin D receptor binding [GO:0042809]; zinc ion binding [GO:0008270]
d2qpza__d1z01d1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	aromatic compound catabolic process [GO:0019439]				2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d2qq1a__d2nrpb3__1			Aquificae	Proteobacteria	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d2qq1b__d3mchc___1			Aquificae	Deinococcus-Thermus	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]				
d2qq1c__d5erta2__1		Metazoa	Aquificae	Chordata	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization membrane [GO:0099634]; postsynaptic specialization, intracellular component [GO:0099091]; synapse [GO:0045202]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]; establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein homooligomerization [GO:0051260]; protein targeting [GO:0006605]; synapse assembly [GO:0007416]		cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glycinergic synapse [GO:0098690]; inhibitory synapse [GO:0060077]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; postsynaptic specialization [GO:0099572]; postsynaptic specialization, intracellular component [GO:0099091]; postsynaptic specialization membrane [GO:0099634]; synapse [GO:0045202]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; protein binding, bridging [GO:0030674]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; tubulin binding [GO:0015631]
d2qq3a__d4q1jb___1			Firmicutes	Firmicutes	catalytic activity [GO:0003824]	cytoplasm [GO:0005737]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; antibiotic biosynthetic process [GO:0017000]; fatty acid beta-oxidation [GO:0006635]		antibiotic biosynthetic process [GO:0017000]; fatty acid beta-oxidation [GO:0006635]		cytoplasm [GO:0005737]	catalytic activity [GO:0003824]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]
d2qq3c__d1uytb1__1		Fungi	Firmicutes	Ascomycota	catalytic activity [GO:0003824]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]		acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]		acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d2qq3d__d2zl2d___1			Firmicutes	Proteobacteria	catalytic activity [GO:0003824]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	catalytic activity [GO:0003824]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d2qq4f__d2l4xa___1			Deinococcus-Thermus	Proteobacteria	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]; iron-sulfur cluster assembly [GO:0016226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]	iron-sulfur cluster assembly [GO:0016226]	cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]	2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]
d2qq4g__d1wfza1__1		Metazoa	Deinococcus-Thermus	Chordata	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]; iron-sulfur cluster assembly [GO:0016226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferrous iron binding [GO:0008198]; molecular adaptor activity [GO:0060090]; cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]; negative regulation of iron ion import across plasma membrane [GO:1904439]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]	iron-sulfur cluster assembly [GO:0016226]	cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]; negative regulation of iron ion import across plasma membrane [GO:1904439]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]	2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferrous iron binding [GO:0008198]; molecular adaptor activity [GO:0060090]
d2qq4i__d3a7aa2__1			Deinococcus-Thermus	Proteobacteria	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]; iron-sulfur cluster assembly [GO:0016226]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; lipoate-protein ligase activity [GO:0016979]; lipoyltransferase activity [GO:0017118]; protein lipoylation [GO:0009249]	iron-sulfur cluster assembly [GO:0016226]	protein lipoylation [GO:0009249]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]	ATP binding [GO:0005524]; lipoate-protein ligase activity [GO:0016979]; lipoyltransferase activity [GO:0017118]
d2qq4j__d1r9pa1__1			Deinococcus-Thermus	Proteobacteria	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]; iron-sulfur cluster assembly [GO:0016226]	cell [GO:0005623]; cytoplasm [GO:0005737]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferrous iron binding [GO:0008198]; cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]	iron-sulfur cluster assembly [GO:0016226]	cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]		cell [GO:0005623]; cytoplasm [GO:0005737]	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]	2 iron, 2 sulfur cluster binding [GO:0051537]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferrous iron binding [GO:0008198]
d2qqdc__d1n2md___1			Euryarchaeota	Euryarchaeota	arginine decarboxylase activity [GO:0008792]; arginine catabolic process [GO:0006527]	arginine decarboxylase activity [GO:0008792]; arginine catabolic process [GO:0006527]	arginine catabolic process [GO:0006527]	arginine catabolic process [GO:0006527]			arginine decarboxylase activity [GO:0008792]	arginine decarboxylase activity [GO:0008792]
d2qqia2_d2qqma1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]; coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]; coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]	coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]	coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d2qqkl1_d1cdua2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d2qqkl2_d1dqmh1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2qqll1_d2j1kp___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2qqll2_d1knob2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2qqma1_d2pqsc1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]; coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	extracellular region [GO:0005576]; membrane [GO:0016020]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]	extracellular region [GO:0005576]; membrane [GO:0016020]	coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]	
d2qqna__d3ogra4__1	Metazoa	Fungi	Chordata	Ascomycota	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	beta-galactosidase activity [GO:0004565]; carbohydrate metabolic process [GO:0005975]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	carbohydrate metabolic process [GO:0005975]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-galactosidase activity [GO:0004565]
d2qqnl2_d1yeil1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2qqoa2_d3mv011__1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; integral component of postsynaptic membrane [GO:0099055]; membrane [GO:0016020]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; semaphorin receptor activity [GO:0017154]; signaling receptor activity [GO:0038023]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; angiogenesis [GO:0001525]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to leukemia inhibitory factor [GO:1990830]; dorsal root ganglion morphogenesis [GO:1904835]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; negative chemotaxis [GO:0050919]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of postsynapse organization [GO:0099175]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; trigeminal ganglion development [GO:0061551]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]; viral process [GO:0016032]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	angiogenesis [GO:0001525]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to leukemia inhibitory factor [GO:1990830]; dorsal root ganglion morphogenesis [GO:1904835]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; negative chemotaxis [GO:0050919]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of postsynapse organization [GO:0099175]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; trigeminal ganglion development [GO:0061551]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]; viral process [GO:0016032]	lactose catabolic process [GO:0005990]	axon [GO:0030424]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; integral component of postsynaptic membrane [GO:0099055]; membrane [GO:0016020]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116]	beta-galactosidase complex [GO:0009341]	cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; semaphorin receptor activity [GO:0017154]; signaling receptor activity [GO:0038023]; vascular endothelial growth factor-activated receptor activity [GO:0005021]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2qqqb__d3ijyc2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d2qqqd__d3ra7l1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d2qr0a2_d1i7td1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2qr0a2_d5b71a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d2qr0e2_d3b2vh1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2qr0f1_d3vfgl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2qr0g1_d1brec___1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2qr0k2_d3ogog___1	Metazoa	Metazoa	Chordata	Cnidaria	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2qr0l1_d2exwf2__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d2qr0m1_d1ck0l1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2qr0q2_d2esve2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2qr0r1_d1ay1h1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2qr0s1_d1x7qa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2qr0s1_d2ckba1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2qr0t1_d1a6vh___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2qr0w1_d1b0wb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d2qr0w2_d1n0xm2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2qr1g1_d3fhmc1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; protein kinase activator activity [GO:0030295]; carbohydrate metabolic process [GO:0005975]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]	nucleotide binding [GO:0000166]	carbohydrate metabolic process [GO:0005975]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]		AMP binding [GO:0016208]; ATP binding [GO:0005524]; protein kinase activator activity [GO:0030295]	nucleotide binding [GO:0000166]
d2qr5a2_d4dnoc1__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	hydrolase activity [GO:0016787]			cytoplasm [GO:0005737]		serine-type peptidase activity [GO:0008236]	hydrolase activity [GO:0016787]
d2qr5b1_d4an1a1__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d2qr8a__d2jiub___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; magnesium ion binding [GO:0000287]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; ribosomal protein S6 kinase activity [GO:0004711]; cell cycle [GO:0007049]; intracellular signal transduction [GO:0035556]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; response to lipopolysaccharide [GO:0032496]; toll-like receptor signaling pathway [GO:0002224]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell cycle [GO:0007049]; intracellular signal transduction [GO:0035556]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; response to lipopolysaccharide [GO:0032496]; toll-like receptor signaling pathway [GO:0002224]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	ATP binding [GO:0005524]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; magnesium ion binding [GO:0000287]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; ribosomal protein S6 kinase activity [GO:0004711]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2qrce1_d3lqna___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; protein kinase activator activity [GO:0030295]; carbohydrate metabolic process [GO:0005975]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]		carbohydrate metabolic process [GO:0005975]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]		AMP binding [GO:0016208]; ATP binding [GO:0005524]; protein kinase activator activity [GO:0030295]	
d2qrcg1_d3kpca___1	Fungi		Ascomycota	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; protein kinase activator activity [GO:0030295]; carbohydrate metabolic process [GO:0005975]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]		carbohydrate metabolic process [GO:0005975]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]		AMP binding [GO:0016208]; ATP binding [GO:0005524]; protein kinase activator activity [GO:0030295]	
d2qrwa__d1ngkf___1			Actinobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d2qrwe__d4maxb___1			Actinobacteria	Cyanobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2qrwj__d3uh7b___1		Metazoa	Actinobacteria	Mollusca	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2qrwk__d1jy7q___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2qrza__d3p3me1__1	Metazoa		Chordata		apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]		actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]		apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]		apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	
d2qrza__d5cb8a___1	Metazoa		Chordata	Cyanobacteria	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]		apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d2qs1b__d2xwka1__1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	
d2qs2b__d1y3na1__1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	metal ion binding [GO:0046872]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]		cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]		drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	metal ion binding [GO:0046872]
d2qs3b__d1al3a___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; cysteine biosynthetic process [GO:0019344]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	cysteine biosynthetic process [GO:0019344]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2qs4c__d4pp0a___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	nitrogen compound transport [GO:0071705]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	ligand-gated ion channel activity [GO:0015276]
d2qscl1_d4k3ha___1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2qscl2_d2ipka1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d2qspa__d3pi2b___1	Metazoa	Metazoa	Chordata	Mollusca	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2qssa__d2hz2a___1	Metazoa		Chordata	Cyanobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	cell [GO:0005623]; cytoplasm [GO:0005737]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d2qssd__d1hdbb___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2qsua__d1u1gd___1	Viridiplantae		Streptophyta	Proteobacteria	cytosol [GO:0005829]; plasma membrane [GO:0005886]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]
d2qsua__d3qpbe___1	Viridiplantae		Streptophyta	Firmicutes	cytosol [GO:0005829]; plasma membrane [GO:0005886]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]	uridine phosphorylase activity [GO:0004850]
d2qt6a1_d1tsbd___1	Fungi		Basidiomycota		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]						copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	
d2qt6a2_d3ft0a___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2qt6a3_d4a68a2__1	Fungi		Basidiomycota	Firmicutes	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2qt6b1_d3fu9b3__1	Fungi	Fungi	Basidiomycota	Ascomycota	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2qt6b2_d4haka1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d2qtaa3_d1w85h2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	cytosol [GO:0005829]; membrane [GO:0016020]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2qtab3_d5nd6a3__1		Viridiplantae	Proteobacteria	Chlorophyta	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]	pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]	transketolase activity [GO:0004802]
d2qtca3_d1qgdb3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	glycolytic process [GO:0006096]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d2qteb__d5vcoa2__1	Metazoa	Metazoa	Chordata	Arthropoda	integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]			integral component of membrane [GO:0016021]	extracellular region [GO:0005576]		cysteine-type peptidase activity [GO:0008234]
d2qtna__d3nbka1__1				Actinobacteria		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]		coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d2qtra__d1g8ga2__1		Fungi	Firmicutes	Ascomycota	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	NAD biosynthetic process [GO:0009435]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d2qtta__d3enzb1__1	Viridiplantae		Streptophyta	Apicomplexa	cytosol [GO:0005829]; plasma membrane [GO:0005886]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]; plasma membrane [GO:0005886]		adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]	purine-nucleoside phosphorylase activity [GO:0004731]
d2qu7b__d1lbga2__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]		cytosol [GO:0005829]	DNA binding [GO:0003677]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]
d2quda1_d4zora___1					viral capsid [GO:0019028]	T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]		regulation of translation [GO:0006417]	viral capsid [GO:0019028]	T=3 icosahedral viral capsid [GO:0039617]		identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2qutd__d5hwnc1__1	Metazoa		Chordata	Proteobacteria	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	5-dehydro-4-deoxyglucarate dehydratase activity [GO:0047448]; D-glucarate catabolic process [GO:0042838]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	D-glucarate catabolic process [GO:0042838]	I band [GO:0031674]; M band [GO:0031430]		fructose-bisphosphate aldolase activity [GO:0004332]	5-dehydro-4-deoxyglucarate dehydratase activity [GO:0047448]
d2quvd__d1w8rj___1	Metazoa		Chordata		I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]		glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]		I band [GO:0031674]; M band [GO:0031430]		fructose-bisphosphate aldolase activity [GO:0004332]	
d2quxd__d2b2gc___1					viral capsid [GO:0019028]	T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]		regulation of translation [GO:0006417]	viral capsid [GO:0019028]	T=3 icosahedral viral capsid [GO:0039617]		identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2quyb__d2fnyg___1			Firmicutes		penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]				penicillin amidase activity [GO:0008953]	
d2quyb__d3mg4d___1		Fungi	Firmicutes	Ascomycota	penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	penicillin amidase activity [GO:0008953]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2qvba__d3hysa1__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; plasma membrane [GO:0005886]; haloalkane dehalogenase activity [GO:0018786]; halogenated hydrocarbon catabolic process [GO:0042206]	peroxidase activity [GO:0004601]	halogenated hydrocarbon catabolic process [GO:0042206]		cell wall [GO:0005618]; plasma membrane [GO:0005886]		haloalkane dehalogenase activity [GO:0018786]	peroxidase activity [GO:0004601]
d2qvfb1_d2omwb1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d2qvia1_d1zvnb1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; fascia adherens [GO:0005916]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic specialization membrane [GO:0099060]; integral component of presynaptic active zone membrane [GO:0099059]; intercalated disc [GO:0014704]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; T-tubule [GO:0030315]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]; gamma-catenin binding [GO:0045295]; identical protein binding [GO:0042802]; nitric-oxide synthase binding [GO:0050998]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; adherens junction organization [GO:0034332]; blood vessel morphogenesis [GO:0048514]; brain morphogenesis [GO:0048854]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cerebral cortex development [GO:0021987]; glial cell differentiation [GO:0010001]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homeostasis of number of cells [GO:0048872]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neuroepithelial cell differentiation [GO:0060563]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; protein localization to plasma membrane [GO:0072659]; radial glial cell differentiation [GO:0060019]; regulation of axonogenesis [GO:0050770]; regulation of myelination [GO:0031641]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]; regulation of postsynaptic density protein 95 clustering [GO:1902897]; regulation of protein localization [GO:0032880]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synaptic transmission, glutamatergic [GO:0051966]; striated muscle cell differentiation [GO:0051146]; synapse assembly [GO:0007416]; telencephalon development [GO:0021537]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	adherens junction organization [GO:0034332]; blood vessel morphogenesis [GO:0048514]; brain morphogenesis [GO:0048854]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cerebral cortex development [GO:0021987]; glial cell differentiation [GO:0010001]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homeostasis of number of cells [GO:0048872]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neuroepithelial cell differentiation [GO:0060563]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; protein localization to plasma membrane [GO:0072659]; radial glial cell differentiation [GO:0060019]; regulation of axonogenesis [GO:0050770]; regulation of myelination [GO:0031641]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]; regulation of postsynaptic density protein 95 clustering [GO:1902897]; regulation of protein localization [GO:0032880]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synaptic transmission, glutamatergic [GO:0051966]; striated muscle cell differentiation [GO:0051146]; synapse assembly [GO:0007416]; telencephalon development [GO:0021537]	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell surface [GO:0009986]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; fascia adherens [GO:0005916]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic specialization membrane [GO:0099060]; integral component of presynaptic active zone membrane [GO:0099059]; intercalated disc [GO:0014704]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; T-tubule [GO:0030315]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]; gamma-catenin binding [GO:0045295]; identical protein binding [GO:0042802]; nitric-oxide synthase binding [GO:0050998]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]	calcium ion binding [GO:0005509]
d2qvia2_d5n4ha1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; fascia adherens [GO:0005916]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic specialization membrane [GO:0099060]; integral component of presynaptic active zone membrane [GO:0099059]; intercalated disc [GO:0014704]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; T-tubule [GO:0030315]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]; gamma-catenin binding [GO:0045295]; identical protein binding [GO:0042802]; nitric-oxide synthase binding [GO:0050998]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; adherens junction organization [GO:0034332]; blood vessel morphogenesis [GO:0048514]; brain morphogenesis [GO:0048854]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cerebral cortex development [GO:0021987]; glial cell differentiation [GO:0010001]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homeostasis of number of cells [GO:0048872]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neuroepithelial cell differentiation [GO:0060563]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; protein localization to plasma membrane [GO:0072659]; radial glial cell differentiation [GO:0060019]; regulation of axonogenesis [GO:0050770]; regulation of myelination [GO:0031641]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]; regulation of postsynaptic density protein 95 clustering [GO:1902897]; regulation of protein localization [GO:0032880]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synaptic transmission, glutamatergic [GO:0051966]; striated muscle cell differentiation [GO:0051146]; synapse assembly [GO:0007416]; telencephalon development [GO:0021537]	basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; contractile ring [GO:0070938]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystroglycan complex [GO:0016011]; dystrophin-associated glycoprotein complex [GO:0016010]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; membrane [GO:0016020]; membrane raft [GO:0045121]; node of Ranvier [GO:0033268]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]; synapse [GO:0045202]; actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; calcium ion binding [GO:0005509]; dystroglycan binding [GO:0002162]; laminin binding [GO:0043236]; laminin-1 binding [GO:0043237]; SH2 domain binding [GO:0042169]; structural constituent of muscle [GO:0008307]; tubulin binding [GO:0015631]; vinculin binding [GO:0017166]; aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; Schwann cell development [GO:0014044]; skeletal muscle tissue regeneration [GO:0043403]	adherens junction organization [GO:0034332]; blood vessel morphogenesis [GO:0048514]; brain morphogenesis [GO:0048854]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell migration [GO:0016477]; cell morphogenesis [GO:0000902]; cerebral cortex development [GO:0021987]; glial cell differentiation [GO:0010001]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homeostasis of number of cells [GO:0048872]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neuroepithelial cell differentiation [GO:0060563]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; protein localization to plasma membrane [GO:0072659]; radial glial cell differentiation [GO:0060019]; regulation of axonogenesis [GO:0050770]; regulation of myelination [GO:0031641]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]; regulation of postsynaptic density protein 95 clustering [GO:1902897]; regulation of protein localization [GO:0032880]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synaptic transmission, glutamatergic [GO:0051966]; striated muscle cell differentiation [GO:0051146]; synapse assembly [GO:0007416]; telencephalon development [GO:0021537]	aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; Schwann cell development [GO:0014044]; skeletal muscle tissue regeneration [GO:0043403]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell surface [GO:0009986]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; fascia adherens [GO:0005916]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic specialization membrane [GO:0099060]; integral component of presynaptic active zone membrane [GO:0099059]; intercalated disc [GO:0014704]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; T-tubule [GO:0030315]	basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; contractile ring [GO:0070938]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystroglycan complex [GO:0016011]; dystrophin-associated glycoprotein complex [GO:0016010]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; membrane [GO:0016020]; membrane raft [GO:0045121]; node of Ranvier [GO:0033268]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]; synapse [GO:0045202]	alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]; gamma-catenin binding [GO:0045295]; identical protein binding [GO:0042802]; nitric-oxide synthase binding [GO:0050998]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]	actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; calcium ion binding [GO:0005509]; dystroglycan binding [GO:0002162]; laminin-1 binding [GO:0043237]; laminin binding [GO:0043236]; SH2 domain binding [GO:0042169]; structural constituent of muscle [GO:0008307]; tubulin binding [GO:0015631]; vinculin binding [GO:0017166]
d2qvqa__d2h1lx2__1		Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]		autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]		ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d2qvqa__d2o61b2__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]
d2qw7h__d4n8xk___1			Cyanobacteria	Cyanobacteria								
d2qw7i__d4n8fb___1			Cyanobacteria	Cyanobacteria								
d2qw8a__d1b16a___1	Viridiplantae	Metazoa	Streptophyta	Arthropoda	oxidoreductase activity [GO:0016491]; phenylpropanoid biosynthetic process [GO:0009699]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]; alcohol metabolic process [GO:0006066]	phenylpropanoid biosynthetic process [GO:0009699]	alcohol metabolic process [GO:0006066]			oxidoreductase activity [GO:0016491]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]
d2qw9a1_d5aqlc2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d2qw9a2_d3h3nx2__1	Metazoa		Chordata	Firmicutes	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d2qw9b1_d3d2fd2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]
d2qwaa__d1n1va2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d2qwaa__d4mjva___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2qwea__d5huma___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2qwla1_d2i7pd1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; nucleus [GO:0005634]; acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]; coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytosol [GO:0005829]; nucleus [GO:0005634]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]
d2qwla2_d2p3rg4__1	Metazoa		Chordata		autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]		axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]		autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	
d2qwla2_d5aqka1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d2qwlb2_d3sk3a1__1	Metazoa		Chordata	Proteobacteria	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]
d2qwma2_d3ldoa2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d2qwmb1_d3fe1b1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	blood microparticle [GO:0072562]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; neutrophil degranulation [GO:0043312]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; neutrophil degranulation [GO:0043312]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	blood microparticle [GO:0072562]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d2qwmb2_d5e26b2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; aerobic respiration [GO:0009060]; coenzyme A biosynthetic process [GO:0015937]; coenzyme biosynthetic process [GO:0009108]; mitochondrion morphogenesis [GO:0070584]; pantothenate metabolic process [GO:0015939]; phosphorylation [GO:0016310]; regulation of bile acid metabolic process [GO:1904251]; regulation of fatty acid metabolic process [GO:0019217]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of triglyceride metabolic process [GO:0090207]; spermatid development [GO:0007286]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	aerobic respiration [GO:0009060]; coenzyme A biosynthetic process [GO:0015937]; coenzyme biosynthetic process [GO:0009108]; mitochondrion morphogenesis [GO:0070584]; pantothenate metabolic process [GO:0015939]; phosphorylation [GO:0016310]; regulation of bile acid metabolic process [GO:1904251]; regulation of fatty acid metabolic process [GO:0019217]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of triglyceride metabolic process [GO:0090207]; spermatid development [GO:0007286]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d2qwna1_d5br9d1__1	Metazoa		Chordata	Proteobacteria	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	
d2qwna2_d1k8kb1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	actin filament binding [GO:0051015]
d2qwoa1_d1ngga1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d2qwoa2_d3w0la2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; fructose-6-phosphate binding [GO:0070095]; carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]; negative regulation of glucokinase activity [GO:0033132]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]; negative regulation of glucokinase activity [GO:0033132]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	fructose-6-phosphate binding [GO:0070095]
d2qwpa1_d2qwqa2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d2qwqa1_d1yxqa2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2qwqb__d1n4ca1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; vesicle [GO:0031982]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; protein domain specific binding [GO:0019904]; protein tyrosine phosphatase activity [GO:0004725]; SH3 domain binding [GO:0017124]; clathrin coat disassembly [GO:0072318]; clathrin-dependent endocytosis [GO:0072583]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle uncoating [GO:0016191]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	clathrin coat disassembly [GO:0072318]; clathrin-dependent endocytosis [GO:0072583]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle uncoating [GO:0016191]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; vesicle [GO:0031982]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; protein domain specific binding [GO:0019904]; protein tyrosine phosphatase activity [GO:0004725]; SH3 domain binding [GO:0017124]
d2qwsa__d5svud___1		Viridiplantae	Proteobacteria	Streptophyta	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; photoreceptor activity [GO:0009881]; circadian rhythm [GO:0007623]; flower development [GO:0009908]; protein ubiquitination [GO:0016567]; protein-chromophore linkage [GO:0018298]; response to blue light [GO:0009637]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	circadian rhythm [GO:0007623]; flower development [GO:0009908]; protein-chromophore linkage [GO:0018298]; protein ubiquitination [GO:0016567]; response to blue light [GO:0009637]		cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	photoreceptor activity [GO:0009881]
d2qwxa__d2moka___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2qx1a1_d2hdbb1__1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d2qx1a2_d1teda2__1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2qx1b1_d1u0wd1__1		Viridiplantae	Actinobacteria	Streptophyta	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	naringenin-chalcone synthase activity [GO:0016210]
d2qx1b2_d4ls5a1__1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d2qx4a__d3gfse___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d2qx6b__d3f6ra___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2qx7b__d3toxe___1	Viridiplantae		Streptophyta	Proteobacteria	oxidoreductase activity [GO:0016491]; phenylpropanoid biosynthetic process [GO:0009699]	nucleotide binding [GO:0000166]	phenylpropanoid biosynthetic process [GO:0009699]				oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]
d2qx8a__d1czua___1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2qx9a__d1ydgb1__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidation-reduction process [GO:0055114]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]
d2qx9b__d4y9ra1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d2qxac__d1hjcd___1		Metazoa		Chordata		basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]		behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]		basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2qxbb__d4a63e1__1		Metazoa		Chordata		cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]		activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]		cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2qxcd__d3wtuf___1		Metazoa		Chordata		core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]		cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]		core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]
d2qxga__d3tnta___1	Metazoa		Chordata		epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2qxha__d1ct4e___1	Metazoa	Metazoa	Chordata	Chordata	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]		epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	extracellular region [GO:0005576]	peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase inhibitor activity [GO:0004867]
d2qxha__d2bdhc___1	Metazoa	Metazoa	Chordata	Chordata	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2qxtb__d1dwpb1__1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]		lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]
d2qxtb__d1ji3a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	metal ion binding [GO:0046872]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]		lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]
d2qxua__d2lipa___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d2qxud__d3d2bb___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d2qxuh__d5t4ha2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2qxxa__d3loja1__1			Actinobacteria	Actinobacteria	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]			dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2qxzb__d1qjvb___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; lyase activity [GO:0016829]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	polysaccharide catabolic process [GO:0000272]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	lyase activity [GO:0016829]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]
d2qy9a1_d2j45a1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; signal recognition particle binding [GO:0005047]; protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]	signal recognition particle [GO:0048500]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; signal recognition particle binding [GO:0005047]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d2qyia__d2rdlb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d2qyid__d1af9a2__1	Metazoa		Chordata	Firmicutes	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	digestion [GO:0007586]; proteolysis [GO:0006508]	negative regulation of neurotransmitter secretion [GO:0046929]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d2qyka1_d3dy8b2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of protein kinase A signaling [GO:0010738]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of protein kinase A signaling [GO:0010738]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2qyka1_d4mseb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of protein kinase A signaling [GO:0010738]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of protein kinase A signaling [GO:0010738]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d2qykb1_d3o0ja___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of protein kinase A signaling [GO:0010738]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of protein kinase A signaling [GO:0010738]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d2qynb__d3dy8a2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2qynb__d3snia1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d2qyoa1_d4q48b3__1	Viridiplantae		Streptophyta	Deinococcus-Thermus	isoflavone 7-O-methyltransferase activity [GO:0033800]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; aromatic compound biosynthetic process [GO:0019438]	bacterial nucleoid [GO:0043590]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; replisome [GO:0030894]; 3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; four-way junction helicase activity [GO:0009378]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432]	aromatic compound biosynthetic process [GO:0019438]	DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432]		bacterial nucleoid [GO:0043590]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; replisome [GO:0030894]	isoflavone 7-O-methyltransferase activity [GO:0033800]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	3'-5' DNA helicase activity [GO:0043138]; ATP binding [GO:0005524]; four-way junction helicase activity [GO:0009378]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2qyoa2_d1tw2a2__1	Viridiplantae		Streptophyta	Actinobacteria	isoflavone 7-O-methyltransferase activity [GO:0033800]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; aromatic compound biosynthetic process [GO:0019438]	methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]; daunorubicin biosynthetic process [GO:1901771]	aromatic compound biosynthetic process [GO:0019438]	daunorubicin biosynthetic process [GO:1901771]			isoflavone 7-O-methyltransferase activity [GO:0033800]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]
d2qyoa2_d3p9ca2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	isoflavone 7-O-methyltransferase activity [GO:0033800]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; aromatic compound biosynthetic process [GO:0019438]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	aromatic compound biosynthetic process [GO:0019438]				isoflavone 7-O-methyltransferase activity [GO:0033800]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]
d2qysa__d1a71b2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	oxidoreductase activity [GO:0016491]; phenylpropanoid biosynthetic process [GO:0009699]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	phenylpropanoid biosynthetic process [GO:0009699]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	oxidoreductase activity [GO:0016491]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d2qzpa1_d1e8ma1__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d2qzpb2_d5fv4f___1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]	cytoplasm [GO:0005737]	endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	serine-type peptidase activity [GO:0008236]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d2qzwb__d3ogpa___1	Fungi		Ascomycota		extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; aspartic-type endopeptidase activity [GO:0004190]; adhesion of symbiont to host [GO:0044406]; fungal-type cell wall organization [GO:0031505]; induction by symbiont of defense-related host calcium ion flux [GO:0052391]; induction by symbiont of host defense response [GO:0044416]; induction by symbiont of host immune response [GO:0052559]; nitrogen compound metabolic process [GO:0006807]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; protein metabolic process [GO:0019538]; proteolysis [GO:0006508]; signal peptide processing [GO:0006465]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	adhesion of symbiont to host [GO:0044406]; fungal-type cell wall organization [GO:0031505]; induction by symbiont of defense-related host calcium ion flux [GO:0052391]; induction by symbiont of host defense response [GO:0044416]; induction by symbiont of host immune response [GO:0052559]; nitrogen compound metabolic process [GO:0006807]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; protein metabolic process [GO:0019538]; proteolysis [GO:0006508]; signal peptide processing [GO:0006465]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d2qzxa__d3kdcb___1	Fungi		Ascomycota		extracellular region [GO:0005576]; fungal biofilm matrix [GO:0062040]; fungal-type cell wall [GO:0009277]; aspartic-type endopeptidase activity [GO:0004190]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; fungal biofilm matrix [GO:0062040]; fungal-type cell wall [GO:0009277]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2qzyb1_d2rk8b1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]
d2r04.1_d1vba3___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2r041__d4wm7c___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2r043__d1h8ta___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2r061__d5bnoc___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2r063__d2rs51___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2r063__d4y4yg___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d2r07.1_d4y5zc___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d2r0da1_d4jxha1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; establishment of epithelial cell polarity [GO:0090162]; Golgi vesicle transport [GO:0048193]; positive regulation of cell adhesion [GO:0045785]; regulation of ARF protein signal transduction [GO:0032012]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; inositol 1,4,5 trisphosphate binding [GO:0070679]; lipid binding [GO:0008289]; actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; regulation of ARF protein signal transduction [GO:0032012]	establishment of epithelial cell polarity [GO:0090162]; Golgi vesicle transport [GO:0048193]; positive regulation of cell adhesion [GO:0045785]; regulation of ARF protein signal transduction [GO:0032012]	actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; regulation of ARF protein signal transduction [GO:0032012]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle [GO:0001726]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; inositol 1,4,5 trisphosphate binding [GO:0070679]; lipid binding [GO:0008289]
d2r0da2_d1tqza1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; establishment of epithelial cell polarity [GO:0090162]; Golgi vesicle transport [GO:0048193]; positive regulation of cell adhesion [GO:0045785]; regulation of ARF protein signal transduction [GO:0032012]	clathrin vesicle coat [GO:0030125]; clathrin-coated pit [GO:0005905]; plasma membrane [GO:0005886]; endocytosis [GO:0006897]; protein transport [GO:0015031]	establishment of epithelial cell polarity [GO:0090162]; Golgi vesicle transport [GO:0048193]; positive regulation of cell adhesion [GO:0045785]; regulation of ARF protein signal transduction [GO:0032012]	endocytosis [GO:0006897]; protein transport [GO:0015031]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ruffle [GO:0001726]	clathrin-coated pit [GO:0005905]; clathrin vesicle coat [GO:0030125]; plasma membrane [GO:0005886]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; guanyl-nucleotide exchange factor activity [GO:0005085]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]	
d2r0fb__d2d3rb___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]			cell wall [GO:0005618]; extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2r0hc__d2dvda___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]			cell wall [GO:0005618]; extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2r0kh1_d1hxmc2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	proteolysis [GO:0006508]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	transmembrane signaling receptor activity [GO:0004888]
d2r0lh2_d4wfhf1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]; identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]; cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]	proteolysis [GO:0006508]	cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]
d2r0ma1_d2fonc3__1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA dehydrogenase activity [GO:0004361]; glutaryl-CoA hydrolase activity [GO:0044466]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lysine catabolic process [GO:0006554]; tryptophan metabolic process [GO:0006568]	peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676]	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lysine catabolic process [GO:0006554]; tryptophan metabolic process [GO:0006568]	fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	peroxisome [GO:0005777]	fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA dehydrogenase activity [GO:0004361]; glutaryl-CoA hydrolase activity [GO:0044466]	acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]
d2r0na1_d1t9ga1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA dehydrogenase activity [GO:0004361]; glutaryl-CoA hydrolase activity [GO:0044466]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lysine catabolic process [GO:0006554]; tryptophan metabolic process [GO:0006568]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lysine catabolic process [GO:0006554]; tryptophan metabolic process [GO:0006568]	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA dehydrogenase activity [GO:0004361]; glutaryl-CoA hydrolase activity [GO:0044466]	electron transfer activity [GO:0009055]
d2r0ob2_d1bhda___1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; neuron projection [GO:0043005]; nuclear body [GO:0016604]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; pseudopodium [GO:0031143]; ribonucleoprotein complex [GO:1990904]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor transcription coactivator activity [GO:0030374]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; retinoic acid receptor binding [GO:0042974]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; actin filament bundle assembly [GO:0051017]; bicellular tight junction assembly [GO:0070830]; negative regulation of cellular component movement [GO:0051271]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; platelet degranulation [GO:0002576]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular component movement [GO:0051272]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pinocytosis [GO:0048549]; positive regulation of sodium:proton antiporter activity [GO:0032417]; protein localization to bicellular tight junction [GO:1902396]; protein transport [GO:0015031]; regulation of apoptotic process [GO:0042981]; regulation of nucleic acid-templated transcription [GO:1903506]; response to hypoxia [GO:0001666]; retinoic acid receptor signaling pathway [GO:0048384]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vesicle transport along actin filament [GO:0030050]	cell junction [GO:0030054]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystrophin-associated glycoprotein complex [GO:0016010]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; growth cone [GO:0030426]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; protein kinase binding [GO:0019901]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]; muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; response to denervation involved in regulation of muscle adaptation [GO:0014894]	actin filament bundle assembly [GO:0051017]; bicellular tight junction assembly [GO:0070830]; negative regulation of cellular component movement [GO:0051271]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; platelet degranulation [GO:0002576]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular component movement [GO:0051272]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pinocytosis [GO:0048549]; positive regulation of sodium:proton antiporter activity [GO:0032417]; protein localization to bicellular tight junction [GO:1902396]; protein transport [GO:0015031]; regulation of apoptotic process [GO:0042981]; regulation of nucleic acid-templated transcription [GO:1903506]; response to hypoxia [GO:0001666]; retinoic acid receptor signaling pathway [GO:0048384]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vesicle transport along actin filament [GO:0030050]	muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of sodium ion transmembrane transporter activity [GO:2000649]; response to denervation involved in regulation of muscle adaptation [GO:0014894]	brush border [GO:0005903]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; neuron projection [GO:0043005]; nuclear body [GO:0016604]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; pseudopodium [GO:0031143]; ribonucleoprotein complex [GO:1990904]; stress fiber [GO:0001725]; Z disc [GO:0030018]	cell junction [GO:0030054]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystrophin-associated glycoprotein complex [GO:0016010]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; growth cone [GO:0030426]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; chromatin DNA binding [GO:0031490]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor transcription coactivator activity [GO:0030374]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; retinoic acid receptor binding [GO:0042974]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; protein kinase binding [GO:0019901]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]
d2r0ra__d3bqqd___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule membrane [GO:0035577]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; beta-galactosidase activity [GO:0004565]; enzyme activator activity [GO:0008047]; G protein-coupled receptor binding [GO:0001664]; ganglioside GM1 binding [GO:1905573]; ganglioside GM2 binding [GO:1905574]; ganglioside GM3 binding [GO:1905575]; ganglioside GP1c binding [GO:1905577]; ganglioside GT1b binding [GO:1905576]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; cochlea development [GO:0090102]; corneocyte development [GO:0003335]; cornified envelope assembly [GO:1903575]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; G protein-coupled receptor signaling pathway [GO:0007186]; galactosylceramide catabolic process [GO:0006683]; ganglioside GM1 transport to membrane [GO:1905572]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; micturition [GO:0060073]; myelination [GO:0042552]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]; sensory perception of sound [GO:0007605]; walking behavior [GO:0090659]	azurophil granule membrane [GO:0035577]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; beta-galactosidase activity [GO:0004565]; enzyme activator activity [GO:0008047]; G protein-coupled receptor binding [GO:0001664]; ganglioside GM1 binding [GO:1905573]; ganglioside GM2 binding [GO:1905574]; ganglioside GM3 binding [GO:1905575]; ganglioside GP1c binding [GO:1905577]; ganglioside GT1b binding [GO:1905576]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; cochlea development [GO:0090102]; corneocyte development [GO:0003335]; cornified envelope assembly [GO:1903575]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; G protein-coupled receptor signaling pathway [GO:0007186]; galactosylceramide catabolic process [GO:0006683]; ganglioside GM1 transport to membrane [GO:1905572]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; micturition [GO:0060073]; myelination [GO:0042552]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]; sensory perception of sound [GO:0007605]; walking behavior [GO:0090659]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; cochlea development [GO:0090102]; corneocyte development [GO:0003335]; cornified envelope assembly [GO:1903575]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; galactosylceramide catabolic process [GO:0006683]; ganglioside GM1 transport to membrane [GO:1905572]; glycosphingolipid metabolic process [GO:0006687]; G protein-coupled receptor signaling pathway [GO:0007186]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; micturition [GO:0060073]; myelination [GO:0042552]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]; sensory perception of sound [GO:0007605]; walking behavior [GO:0090659]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; cochlea development [GO:0090102]; corneocyte development [GO:0003335]; cornified envelope assembly [GO:1903575]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; galactosylceramide catabolic process [GO:0006683]; ganglioside GM1 transport to membrane [GO:1905572]; glycosphingolipid metabolic process [GO:0006687]; G protein-coupled receptor signaling pathway [GO:0007186]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; micturition [GO:0060073]; myelination [GO:0042552]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]; sensory perception of sound [GO:0007605]; walking behavior [GO:0090659]	azurophil granule membrane [GO:0035577]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886]	azurophil granule membrane [GO:0035577]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886]	beta-galactosidase activity [GO:0004565]; enzyme activator activity [GO:0008047]; ganglioside GM1 binding [GO:1905573]; ganglioside GM2 binding [GO:1905574]; ganglioside GM3 binding [GO:1905575]; ganglioside GP1c binding [GO:1905577]; ganglioside GT1b binding [GO:1905576]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	beta-galactosidase activity [GO:0004565]; enzyme activator activity [GO:0008047]; ganglioside GM1 binding [GO:1905573]; ganglioside GM2 binding [GO:1905574]; ganglioside GM3 binding [GO:1905575]; ganglioside GP1c binding [GO:1905577]; ganglioside GT1b binding [GO:1905576]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d2r0wl2_d5cp3a1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2r0zl2_d3stla1__1	Metazoa		Chordata	Actinobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	voltage-gated potassium channel complex [GO:0008076]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d2r1da1_d2gntb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]		axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2r1db1_d4ym3a___1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]	angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	cell adhesion [GO:0007155]	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2r1df1_d1loc.3__1	Metazoa	Viridiplantae	Chordata	Streptophyta	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	mannose binding [GO:0005537]	angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]		axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]	mannose binding [GO:0005537]
d2r1dh1_d3akqa___1	Metazoa	Fungi	Chordata	Ascomycota	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	xylan catabolic process [GO:0045493]	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]	endo-1,4-beta-xylanase activity [GO:0031176]
d2r1gg1_d2vhoe1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	
d2r1hc__d4h0mo___1	Metazoa		Chordata	Cyanobacteria	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2r1ra2_d5a0uh___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	carbon-nitrogen lyase activity [GO:0016840]; choline catabolic process [GO:0042426]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	choline catabolic process [GO:0042426]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	carbon-nitrogen lyase activity [GO:0016840]
d2r1rc2_d5a0ua___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	carbon-nitrogen lyase activity [GO:0016840]; choline catabolic process [GO:0042426]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	choline catabolic process [GO:0042426]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	carbon-nitrogen lyase activity [GO:0016840]
d2r1ua__d4e08b___1	Metazoa	Metazoa	Chordata	Arthropoda	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; protein deglycase activity [GO:0036524]; adult locomotory behavior [GO:0008344]; cellular response to reactive oxygen species [GO:0034614]; guanine deglycation, glyoxal removal [GO:0106046]; larval locomotory behavior [GO:0008345]; negative regulation of developmental growth [GO:0048640]; phosphatidylinositol 3-kinase signaling [GO:0014065]; protein deglycation, glyoxal removal [GO:0036529]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of mitochondrial ATP synthesis coupled electron transport [GO:1905446]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of synaptic plasticity [GO:0048167]; response to oxidative stress [GO:0006979]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	adult locomotory behavior [GO:0008344]; cellular response to reactive oxygen species [GO:0034614]; guanine deglycation, glyoxal removal [GO:0106046]; larval locomotory behavior [GO:0008345]; negative regulation of developmental growth [GO:0048640]; phosphatidylinositol 3-kinase signaling [GO:0014065]; protein deglycation, glyoxal removal [GO:0036529]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of mitochondrial ATP synthesis coupled electron transport [GO:1905446]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of synaptic plasticity [GO:0048167]; response to oxidative stress [GO:0006979]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]	oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; protein deglycase activity [GO:0036524]
d2r1xa2_d1s5ih1__1	Metazoa	Metazoa	Chordata	Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2r1xa2_d4y4fb___1	Metazoa	Metazoa	Chordata	Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d2r1xb1_d3pwla2__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2r1ya1_d4wwka1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2r1yb1_d1e6oh1__1	Metazoa		Chordata									
d2r1yb1_d3oxrb1__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2r24a__d1xjbb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; G protein-coupled receptor signaling pathway [GO:0007186]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein kinase B signaling [GO:0051897]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytosol [GO:0005829]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]
d2r25a__d1tqga1__1	Fungi		Ascomycota	Thermotogae	cytoplasm [GO:0005737]; nucleus [GO:0005634]; histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]; osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]; chemotaxis [GO:0006935]	osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	chemotaxis [GO:0006935]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]
d2r26d__d1csha___1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]; carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]	citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]
d2r28a__d1rtp3___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cochlea development [GO:0090102]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cochlea development [GO:0090102]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d2r29l2_d2akrb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2r2ba1_d4uv4l2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2r2bb1_d1iebc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2r2eb1_d4n1ca___1		Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2r2fa__d3ta8a___1			Proteobacteria	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2r2fb__d3ised___1			Proteobacteria	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2r2ha1_d3cfjh1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular space [GO:0005615]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2r2ha2_d4n0fk2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2r2ha2_d5ty6l2__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]		metal ion binding [GO:0046872]	
d2r2hb1_d1h15a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	immune response [GO:0006955]; immunoglobulin production [GO:0002377]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	extracellular space [GO:0005615]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	metal ion binding [GO:0046872]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d2r2na__d3l8ab___1	Metazoa		Chordata	Firmicutes	mitochondrial matrix [GO:0005759]; 2-aminoadipate transaminase activity [GO:0047536]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; 2-oxoglutarate metabolic process [GO:0006103]; alpha-amino acid metabolic process [GO:1901605]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine catabolic process [GO:0006554]; tryptophan catabolic process [GO:0006569]	cystathionine beta-lyase activity [GO:0004121]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]	2-oxoglutarate metabolic process [GO:0006103]; alpha-amino acid metabolic process [GO:1901605]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine catabolic process [GO:0006554]; tryptophan catabolic process [GO:0006569]	biosynthetic process [GO:0009058]	mitochondrial matrix [GO:0005759]		2-aminoadipate transaminase activity [GO:0047536]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	cystathionine beta-lyase activity [GO:0004121]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d2r2nb__d4zdoa___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; 2-aminoadipate transaminase activity [GO:0047536]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; 2-oxoglutarate metabolic process [GO:0006103]; alpha-amino acid metabolic process [GO:1901605]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine catabolic process [GO:0006554]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; transferase activity, transferring selenium-containing groups [GO:0016785]; tRNA binding [GO:0000049]; selenocysteine incorporation [GO:0001514]; selenocysteine metabolic process [GO:0016259]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]	2-oxoglutarate metabolic process [GO:0006103]; alpha-amino acid metabolic process [GO:1901605]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine catabolic process [GO:0006554]; tryptophan catabolic process [GO:0006569]	selenocysteine incorporation [GO:0001514]; selenocysteine metabolic process [GO:0016259]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]	mitochondrial matrix [GO:0005759]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	2-aminoadipate transaminase activity [GO:0047536]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	transferase activity, transferring selenium-containing groups [GO:0016785]; tRNA binding [GO:0000049]
d2r2nb__d5gvpb___1	Metazoa		Chordata	Apicomplexa	mitochondrial matrix [GO:0005759]; 2-aminoadipate transaminase activity [GO:0047536]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; 2-oxoglutarate metabolic process [GO:0006103]; alpha-amino acid metabolic process [GO:1901605]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine catabolic process [GO:0006554]; tryptophan catabolic process [GO:0006569]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	2-oxoglutarate metabolic process [GO:0006103]; alpha-amino acid metabolic process [GO:1901605]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine catabolic process [GO:0006554]; tryptophan catabolic process [GO:0006569]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	mitochondrial matrix [GO:0005759]		2-aminoadipate transaminase activity [GO:0047536]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d2r2nc__d1i48i___1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial matrix [GO:0005759]; 2-aminoadipate transaminase activity [GO:0047536]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; 2-oxoglutarate metabolic process [GO:0006103]; alpha-amino acid metabolic process [GO:1901605]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine catabolic process [GO:0006554]; tryptophan catabolic process [GO:0006569]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	2-oxoglutarate metabolic process [GO:0006103]; alpha-amino acid metabolic process [GO:1901605]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine catabolic process [GO:0006554]; tryptophan catabolic process [GO:0006569]	transsulfuration [GO:0019346]	mitochondrial matrix [GO:0005759]		2-aminoadipate transaminase activity [GO:0047536]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d2r2qa1_d2c7nj1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cell body [GO:0044297]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendrite membrane [GO:0032590]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; intracellular [GO:0005622]; microtubule [GO:0005874]; beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; Tat protein binding [GO:0030957]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cell body [GO:0044297]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendrite membrane [GO:0032590]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; intracellular [GO:0005622]; microtubule [GO:0005874]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; Tat protein binding [GO:0030957]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2r2qb1_d2gbkd___1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cell body [GO:0044297]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendrite membrane [GO:0032590]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; intracellular [GO:0005622]; microtubule [GO:0005874]; beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; Tat protein binding [GO:0030957]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cell body [GO:0044297]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendrite membrane [GO:0032590]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; intracellular [GO:0005622]; microtubule [GO:0005874]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; Tat protein binding [GO:0030957]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2r2wu__d3sudc___1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2r3da__d1pafb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2r3tb__d2g22a___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d2r3vb2_d1h73a2__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; peroxisome [GO:0005777]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]; cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; negative regulation of inflammatory response [GO:0050728]; regulation of cholesterol biosynthetic process [GO:0045540]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]	cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; negative regulation of inflammatory response [GO:0050728]; regulation of cholesterol biosynthetic process [GO:0045540]	threonine biosynthetic process [GO:0009088]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; peroxisome [GO:0005777]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]	ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]
d2r3vb2_d1kkha2__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; peroxisome [GO:0005777]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]; cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; negative regulation of inflammatory response [GO:0050728]; regulation of cholesterol biosynthetic process [GO:0045540]	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]	cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; negative regulation of inflammatory response [GO:0050728]; regulation of cholesterol biosynthetic process [GO:0045540]	isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; peroxisome [GO:0005777]	cytosol [GO:0005829]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; mevalonate kinase activity [GO:0004496]
d2r3wa__d4y4ua___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2r3wb__d3lzya___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2r3xa1_d5an1e2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d2r3xb1_d2gdrc2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d2r3xb2_d5dvbc1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to oxidative stress [GO:0006979]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]
d2r43a__d1k6tb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2r43a__d5p3za___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2r43b__d3fx5a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2r4aa__d1ojia___1		Fungi		Ascomycota		extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		cellulase activity [GO:0008810]
d2r4hc1_d4nnlb___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alpha-actinin binding [GO:0051393]; ATP binding [GO:0005524]; molecular adaptor activity [GO:0060090]; protein C-terminus binding [GO:0008022]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; positive regulation of cell-cell adhesion [GO:0022409]; protein-containing complex assembly [GO:0065003]; signal transduction [GO:0007165]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]; activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; positive regulation of cell-cell adhesion [GO:0022409]; protein-containing complex assembly [GO:0065003]; signal transduction [GO:0007165]	activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]	alpha-actinin binding [GO:0051393]; ATP binding [GO:0005524]; molecular adaptor activity [GO:0060090]; protein C-terminus binding [GO:0008022]	beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]
d2r4xa__d3uhqa___1	Metazoa	Metazoa	Mollusca	Mollusca	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2r4xa__d5b13j___1	Metazoa		Mollusca	Rhodophyta	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2r4ya__d1xz5b___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2r56l2_d1of2b1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2r56l2_d1rupl1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2r57a1_d2rjcb2__1	Metazoa	Metazoa	Arthropoda	Chordata	nucleus [GO:0005634]; polytene chromosome [GO:0005700]; PRC1 complex [GO:0035102]; identical protein binding [GO:0042802]; PRC1 complex binding [GO:0140259]; zinc ion binding [GO:0008270]; axonogenesis [GO:0007409]; chromatin organization [GO:0006325]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; ventral cord development [GO:0007419]	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]; chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	axonogenesis [GO:0007409]; chromatin organization [GO:0006325]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; ventral cord development [GO:0007419]	chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	nucleus [GO:0005634]; polytene chromosome [GO:0005700]; PRC1 complex [GO:0035102]	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; PRC1 complex binding [GO:0140259]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]
d2r58a1_d2rhxa1__1	Metazoa	Metazoa	Arthropoda	Chordata	nucleus [GO:0005634]; polytene chromosome [GO:0005700]; PRC1 complex [GO:0035102]; identical protein binding [GO:0042802]; PRC1 complex binding [GO:0140259]; zinc ion binding [GO:0008270]; axonogenesis [GO:0007409]; chromatin organization [GO:0006325]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; ventral cord development [GO:0007419]	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]; chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	axonogenesis [GO:0007409]; chromatin organization [GO:0006325]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; ventral cord development [GO:0007419]	chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	nucleus [GO:0005634]; polytene chromosome [GO:0005700]; PRC1 complex [GO:0035102]	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; PRC1 complex binding [GO:0140259]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]
d2r5ea__d9aata___1	Metazoa	Metazoa	Arthropoda	Chordata	kynurenine aminotransferase activity [GO:0036137]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	biosynthetic process [GO:0009058]	2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	kynurenine aminotransferase activity [GO:0036137]; pyridoxal phosphate binding [GO:0030170]	kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]
d2r5eb__d2eh6a___1	Metazoa		Arthropoda	Aquificae	kynurenine aminotransferase activity [GO:0036137]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process [GO:0006526]	biosynthetic process [GO:0009058]	arginine biosynthetic process [GO:0006526]		cytoplasm [GO:0005737]	kynurenine aminotransferase activity [GO:0036137]; pyridoxal phosphate binding [GO:0030170]	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]
d2r5pb__d1tsua1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2r5pb__d2qmfb___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d2r5pc__d1ivpa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2r5pd__d3b7vb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2r5qb__d1od1a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2r5qd__d5p5ta___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2r61a2_d1d6ec2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	extracellular region [GO:0005576]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d2r61a2_d4rh6c2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d2r69a1_d4l5fe___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	protein dimerization activity [GO:0046983]
d2r69l1_d4gsdl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2r6ka2_d7gssa2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2r6kb2_d1xw6b2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d2r7aa__d5adwc___1			Proteobacteria	Proteobacteria		metal ion binding [GO:0046872]; iron ion transport [GO:0006826]		iron ion transport [GO:0006826]				metal ion binding [GO:0046872]
d2r7aa__d5gj3a1__1			Proteobacteria	Chloroflexi								
d2r7ac__d2afil___1			Proteobacteria	Proteobacteria		molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2r7ad__d3lhsa1__1			Proteobacteria	Firmicutes		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d2r7ad__d4tkub___1			Proteobacteria	Proteobacteria		molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2r7ma1_d1c3oe3__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]		carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2r7na1_d4c5ba1__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]		cytosol [GO:0005829]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2r80a__d2qrwg___1	Metazoa		Chordata	Actinobacteria	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	hemoglobin complex [GO:0005833]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d2r80b__d3wcuc___1	Metazoa	Metazoa	Chordata	Annelida	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2r82a1_d1vbga1__1		Viridiplantae	Firmicutes	Streptophyta	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]	chloroplast [GO:0009507]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; photosynthesis [GO:0015979]; pyruvate metabolic process [GO:0006090]	pyruvate metabolic process [GO:0006090]	photosynthesis [GO:0015979]; pyruvate metabolic process [GO:0006090]		chloroplast [GO:0009507]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]
d2r82a3_d2dika3__1			Firmicutes	Firmicutes	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]	pyruvate metabolic process [GO:0006090]	pyruvate metabolic process [GO:0006090]			ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]
d2r83a1_d2uzpb___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; clathrin-coated vesicle membrane [GO:0030665]; clathrin-sculpted acetylcholine transport vesicle membrane [GO:0060201]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; clathrin-sculpted glutamate transport vesicle membrane [GO:0060203]; clathrin-sculpted monoamine transport vesicle membrane [GO:0070083]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; 1-phosphatidylinositol binding [GO:0005545]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; glutamate secretion [GO:0014047]; membrane organization [GO:0061024]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of exocytosis [GO:0017157]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	calyx of Held [GO:0044305]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; presynaptic cytosol [GO:0099523]; synaptic membrane [GO:0097060]; ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; zinc ion binding [GO:0008270]; chemical synaptic transmission [GO:0007268]; chemosensory behavior [GO:0007635]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; platelet activation [GO:0030168]; positive regulation of mismatch repair [GO:0032425]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of phagocytosis [GO:0050764]; regulation of response to food [GO:0032095]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to morphine [GO:0043278]; response to pain [GO:0048265]; response to psychosocial stress [GO:1990911]; rhythmic process [GO:0048511]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; glutamate secretion [GO:0014047]; membrane organization [GO:0061024]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of exocytosis [GO:0017157]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	chemical synaptic transmission [GO:0007268]; chemosensory behavior [GO:0007635]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; platelet activation [GO:0030168]; positive regulation of mismatch repair [GO:0032425]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of phagocytosis [GO:0050764]; regulation of response to food [GO:0032095]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to morphine [GO:0043278]; response to pain [GO:0048265]; response to psychosocial stress [GO:1990911]; rhythmic process [GO:0048511]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; clathrin-coated vesicle membrane [GO:0030665]; clathrin-sculpted acetylcholine transport vesicle membrane [GO:0060201]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; clathrin-sculpted glutamate transport vesicle membrane [GO:0060203]; clathrin-sculpted monoamine transport vesicle membrane [GO:0070083]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]	calyx of Held [GO:0044305]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; presynaptic cytosol [GO:0099523]; synaptic membrane [GO:0097060]	1-phosphatidylinositol binding [GO:0005545]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]	ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270]
d2r83b2_d1djyb2__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; clathrin-coated vesicle membrane [GO:0030665]; clathrin-sculpted acetylcholine transport vesicle membrane [GO:0060201]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; clathrin-sculpted glutamate transport vesicle membrane [GO:0060203]; clathrin-sculpted monoamine transport vesicle membrane [GO:0070083]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; 1-phosphatidylinositol binding [GO:0005545]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; glutamate secretion [GO:0014047]; membrane organization [GO:0061024]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of exocytosis [GO:0017157]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; glutamate secretion [GO:0014047]; membrane organization [GO:0061024]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of exocytosis [GO:0017157]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; clathrin-coated vesicle membrane [GO:0030665]; clathrin-sculpted acetylcholine transport vesicle membrane [GO:0060201]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; clathrin-sculpted glutamate transport vesicle membrane [GO:0060203]; clathrin-sculpted monoamine transport vesicle membrane [GO:0070083]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	1-phosphatidylinositol binding [GO:0005545]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]
d2r84a1_d4zqic1__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]		cytosol [GO:0005829]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2r85a1_d3jzia1__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2r85b1_d2i80a1__1			Euryarchaeota	Firmicutes	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2r85b1_d2r7la1__1			Euryarchaeota	Euryarchaeota	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]
d2r87b1_d2w6oa1__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2r87d1_d1c3oa4__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]		carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2r87e1_d5m7gf1__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	'de novo' IMP biosynthetic process [GO:0006189]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]		cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d2r87f1_d5xaff1__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	'de novo' IMP biosynthetic process [GO:0006189]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]		cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d2r87f2_d2r82a3__1			Euryarchaeota	Firmicutes	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]	'de novo' IMP biosynthetic process [GO:0006189]	pyruvate metabolic process [GO:0006090]			ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]
d2r8fa2_d2gu0a1__1					host cell cytoplasm [GO:0030430]; ATP binding [GO:0005524]; hydrolase activity, acting on acid anhydrides [GO:0016817]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; viral genome replication [GO:0019079]	host cell cytoplasm [GO:0030430]; ATP binding [GO:0005524]; hydrolase activity, acting on acid anhydrides [GO:0016817]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; viral genome replication [GO:0019079]	viral genome replication [GO:0019079]	viral genome replication [GO:0019079]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	ATP binding [GO:0005524]; hydrolase activity, acting on acid anhydrides [GO:0016817]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; hydrolase activity, acting on acid anhydrides [GO:0016817]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2r8ka1_d2w9bb2__1	Fungi		Ascomycota	Crenarchaeota	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d2r8kb1_d2r8ha1__1	Fungi		Ascomycota	Crenarchaeota	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d2r8oa1_d4jubd3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	mandelate catabolic process [GO:0019596]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]		manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2r8ob1_d1tkcb1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d2r8ob2_d1tkcb1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d2r8pa2_d5deib3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	mandelate catabolic process [GO:0019596]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]		manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2r8pa3_d3exgn2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2r8pb2_d3exfd1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2r8pb3_d2uzab3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	electron transport chain [GO:0022900]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d2r8qa__d1xorb___1		Metazoa		Chordata	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]		apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d2r8ua__d2e9ka1__1	Metazoa	Metazoa	Chordata	Chordata	cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; cell division [GO:0051301]; cell migration [GO:0016477]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of cell migration [GO:0030335]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	filamentous actin [GO:0031941]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; actin binding [GO:0003779]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; NADPH:sulfur oxidoreductase activity [GO:0043914]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; heart development [GO:0007507]; heart looping [GO:0001947]; oxidation-reduction process [GO:0055114]; positive regulation of transcription via serum response element binding [GO:0010735]; sulfur oxidation [GO:0019417]	cell division [GO:0051301]; cell migration [GO:0016477]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of cell migration [GO:0030335]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; heart development [GO:0007507]; heart looping [GO:0001947]; oxidation-reduction process [GO:0055114]; positive regulation of transcription via serum response element binding [GO:0010735]; sulfur oxidation [GO:0019417]	cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]	filamentous actin [GO:0031941]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]	actin binding [GO:0003779]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; NADPH:sulfur oxidoreductase activity [GO:0043914]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d2r8xa__d1z4la___1		Metazoa	Proteobacteria	Chordata	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	lipopolysaccharide biosynthetic process [GO:0009103]	DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]
d2r8xh__d5alma1__1		Metazoa	Proteobacteria	Chordata	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipopolysaccharide biosynthetic process [GO:0009103]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2r8xi__d1k1ed___1			Proteobacteria	Proteobacteria	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]			3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d2r8xi__d3qu4b___1			Proteobacteria	Bacteroidetes	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	lipopolysaccharide biosynthetic process [GO:0009103]				3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]
d2r8xj__d1k1ea___1			Proteobacteria	Proteobacteria	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]			3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d2r8xl__d5ai4a1__1		Metazoa	Proteobacteria	Chordata	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipopolysaccharide biosynthetic process [GO:0009103]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2r8xm__d1xpjd___1			Proteobacteria	Proteobacteria	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]				3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	
d2r8xp__d3wkca1__1		Metazoa	Proteobacteria	Chordata	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipopolysaccharide biosynthetic process [GO:0009103]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2r8ya__d5alka1__1		Metazoa	Proteobacteria	Chordata	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipopolysaccharide biosynthetic process [GO:0009103]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2r8yc__d4hgoc___1			Proteobacteria	Bacteroidetes	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]			3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d2r8yg__d5ue7a___1		Fungi	Proteobacteria	Ascomycota	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]; fungal biofilm matrix [GO:0062040]; phosphomannomutase activity [GO:0004615]; GDP-mannose biosynthetic process [GO:0009298]; mannose metabolic process [GO:0006013]; protein N-linked glycosylation [GO:0006487]; protein targeting to ER [GO:0045047]	lipopolysaccharide biosynthetic process [GO:0009103]	GDP-mannose biosynthetic process [GO:0009298]; mannose metabolic process [GO:0006013]; protein N-linked glycosylation [GO:0006487]; protein targeting to ER [GO:0045047]		cytosol [GO:0005829]; fungal biofilm matrix [GO:0062040]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	phosphomannomutase activity [GO:0004615]
d2r8yj__d2jara___1		Metazoa	Proteobacteria	Chordata	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; phosphatase activity [GO:0016791]; pyrimidine nucleotide binding [GO:0019103]; deoxyribonucleotide catabolic process [GO:0009264]; dephosphorylation [GO:0016311]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]	lipopolysaccharide biosynthetic process [GO:0009103]	deoxyribonucleotide catabolic process [GO:0009264]; dephosphorylation [GO:0016311]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; phosphatase activity [GO:0016791]; pyrimidine nucleotide binding [GO:0019103]
d2r8yk__d4um7d1__1			Proteobacteria	Proteobacteria	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]			3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d2r8yo__d2g1aa___1			Proteobacteria	Proteobacteria	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	lipopolysaccharide biosynthetic process [GO:0009103]			outer membrane-bounded periplasmic space [GO:0030288]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]
d2r8zb__d1nf2b___1			Proteobacteria	Thermotogae	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]	lipopolysaccharide biosynthetic process [GO:0009103]			cytosol [GO:0005829]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]
d2r8zb__d3umgg___1			Proteobacteria	Actinobacteria	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	(S)-2-haloacid dehalogenase activity [GO:0018784]	lipopolysaccharide biosynthetic process [GO:0009103]				3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	(S)-2-haloacid dehalogenase activity [GO:0018784]
d2r8zc__d4hgqa___1			Proteobacteria	Bacteroidetes	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]			3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d2r8zk__d3wk6a1__1		Metazoa	Proteobacteria	Chordata	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipopolysaccharide biosynthetic process [GO:0009103]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2r8zl__d1k1ej___1			Proteobacteria	Proteobacteria	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]			3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d2r8zo__d2wf6a___1			Proteobacteria	Firmicutes	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cytoplasm [GO:0005737]; beta-phosphoglucomutase activity [GO:0008801]; hydrolase activity [GO:0016787]; magnesium ion binding [GO:0000287]; carbohydrate metabolic process [GO:0005975]	lipopolysaccharide biosynthetic process [GO:0009103]	carbohydrate metabolic process [GO:0005975]		cytoplasm [GO:0005737]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	beta-phosphoglucomutase activity [GO:0008801]; hydrolase activity [GO:0016787]; magnesium ion binding [GO:0000287]
d2r8zp__d3qu5b1__1			Proteobacteria	Bacteroidetes	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	lipopolysaccharide biosynthetic process [GO:0009103]				3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]
d2r91a__d3g0sa1__1			Crenarchaeota	Proteobacteria	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d2r94a__d5dbuc___1			Crenarchaeota	Firmicutes	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]		cytoplasm [GO:0005737]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]	deoxyribose-phosphate aldolase activity [GO:0004139]
d2r94b__d1eweb___1		Metazoa	Crenarchaeota	Chordata	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; carbohydrate metabolic process [GO:0005975]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]		I band [GO:0031674]; M band [GO:0031430]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]	fructose-bisphosphate aldolase activity [GO:0004332]
d2r94d__d5dbuh___1			Crenarchaeota	Firmicutes	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]		cytoplasm [GO:0005737]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]	deoxyribose-phosphate aldolase activity [GO:0004139]
d2r96c__d4qofb___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d2r9ba__d3o9ib___1			Apicomplexa		vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2r9bb__d3em4u___1			Apicomplexa		vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2r9eb__d1cssa___1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]; carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]	citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]
d2r9ed__d1vgma___1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [GO:0046912]
d2r9fa__d2pada___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]; aging [GO:0007568]; brain development [GO:0007420]; cellular response to hydrogen peroxide [GO:0070301]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of vascular permeability [GO:0043117]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; response to angiotensin [GO:1990776]; response to arsenic-containing substance [GO:0046685]; self proteolysis [GO:0097264]	cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]	aging [GO:0007568]; brain development [GO:0007420]; cellular response to hydrogen peroxide [GO:0070301]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of vascular permeability [GO:0043117]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; response to angiotensin [GO:1990776]; response to arsenic-containing substance [GO:0046685]; self proteolysis [GO:0097264]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]	cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]
d2r9hf1_d1kgcd1__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2r9hf2_d3npsc1__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2r9ka__d3v14a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2r9kb1_d1pc8b1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2r9kb2_d4lo3b2__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]				carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	
d2r9ua1_d1fo1b___1	Metazoa	Metazoa	Chordata	Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]		mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d2r9ud1_d1ft8a1__1	Metazoa	Metazoa	Chordata	Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]		mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d2ra3b__d3ruoa1__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2ra6b__d3u0dc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; small molecule binding [GO:0036094]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]		antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	small molecule binding [GO:0036094]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d2raca__d2jfcb2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2rala1_d1p5vb___1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	capsule [GO:0042603]; extracellular region [GO:0005576]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	capsule [GO:0042603]; extracellular region [GO:0005576]	metal ion binding [GO:0046872]	
d2rama2_d1kzya___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d2ramb1_d1ayra2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]; G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]	G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]
d2raoa__d2uuml___1	Metazoa		Chordata	Cyanobacteria	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2raoc__d1cpwa___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2rapa__d1hh4a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; midbody [GO:0030496]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; actin cytoskeleton reorganization [GO:0031532]; cellular protein localization [GO:0034613]; cellular response to drug [GO:0035690]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to plasma membrane [GO:0072659]; Rap protein signal transduction [GO:0032486]; regulation of dendrite morphogenesis [GO:0048814]; regulation of JNK cascade [GO:0046328]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	actin cytoskeleton reorganization [GO:0031532]; cellular protein localization [GO:0034613]; cellular response to drug [GO:0035690]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to plasma membrane [GO:0072659]; Rap protein signal transduction [GO:0032486]; regulation of dendrite morphogenesis [GO:0048814]; regulation of JNK cascade [GO:0046328]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	cytosol [GO:0005829]; midbody [GO:0030496]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]
d2razx__d5fcpa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2rb1x__d4bapa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2rb3a1_d1of9a___1	Metazoa		Chordata		azurophil granule membrane [GO:0035577]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; beta-galactosidase activity [GO:0004565]; enzyme activator activity [GO:0008047]; G protein-coupled receptor binding [GO:0001664]; ganglioside GM1 binding [GO:1905573]; ganglioside GM2 binding [GO:1905574]; ganglioside GM3 binding [GO:1905575]; ganglioside GP1c binding [GO:1905577]; ganglioside GT1b binding [GO:1905576]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; cochlea development [GO:0090102]; corneocyte development [GO:0003335]; cornified envelope assembly [GO:1903575]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; G protein-coupled receptor signaling pathway [GO:0007186]; galactosylceramide catabolic process [GO:0006683]; ganglioside GM1 transport to membrane [GO:1905572]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; micturition [GO:0060073]; myelination [GO:0042552]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]; sensory perception of sound [GO:0007605]; walking behavior [GO:0090659]	defense response to bacterium [GO:0042742]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; cochlea development [GO:0090102]; corneocyte development [GO:0003335]; cornified envelope assembly [GO:1903575]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; galactosylceramide catabolic process [GO:0006683]; ganglioside GM1 transport to membrane [GO:1905572]; glycosphingolipid metabolic process [GO:0006687]; G protein-coupled receptor signaling pathway [GO:0007186]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; micturition [GO:0060073]; myelination [GO:0042552]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]; sensory perception of sound [GO:0007605]; walking behavior [GO:0090659]	defense response to bacterium [GO:0042742]	azurophil granule membrane [GO:0035577]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886]		beta-galactosidase activity [GO:0004565]; enzyme activator activity [GO:0008047]; ganglioside GM1 binding [GO:1905573]; ganglioside GM2 binding [GO:1905574]; ganglioside GM3 binding [GO:1905575]; ganglioside GP1c binding [GO:1905577]; ganglioside GT1b binding [GO:1905576]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	
d2rbeb__d1jw7a___1	Metazoa		Chordata		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	
d2rbla__d3b83g1__1	Metazoa		Chordata		basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; interstitial matrix [GO:0005614]; membrane [GO:0016020]; perisynaptic extracellular matrix [GO:0098966]; extracellular matrix structural constituent [GO:0005201]; syndecan binding [GO:0045545]; bud outgrowth involved in lung branching [GO:0060447]; cell adhesion [GO:0007155]; cellular protein metabolic process [GO:0044267]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin D [GO:0071305]; extracellular matrix organization [GO:0030198]; mesenchymal-epithelial cell signaling involved in prostate gland development [GO:0060739]; negative regulation of cell adhesion [GO:0007162]; neuromuscular junction development [GO:0007528]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; post-translational protein modification [GO:0043687]; prostate gland epithelium morphogenesis [GO:0060740]; response to ethanol [GO:0045471]; response to fibroblast growth factor [GO:0071774]; response to mechanical stimulus [GO:0009612]; response to wounding [GO:0009611]; wound healing [GO:0042060]		bud outgrowth involved in lung branching [GO:0060447]; cell adhesion [GO:0007155]; cellular protein metabolic process [GO:0044267]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin D [GO:0071305]; extracellular matrix organization [GO:0030198]; mesenchymal-epithelial cell signaling involved in prostate gland development [GO:0060739]; negative regulation of cell adhesion [GO:0007162]; neuromuscular junction development [GO:0007528]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; post-translational protein modification [GO:0043687]; prostate gland epithelium morphogenesis [GO:0060740]; response to ethanol [GO:0045471]; response to fibroblast growth factor [GO:0071774]; response to mechanical stimulus [GO:0009612]; response to wounding [GO:0009611]; wound healing [GO:0042060]		basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; interstitial matrix [GO:0005614]; membrane [GO:0016020]; perisynaptic extracellular matrix [GO:0098966]		extracellular matrix structural constituent [GO:0005201]; syndecan binding [GO:0045545]	
d2rboa__d2d4ib___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2rbqa__d1qs9a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2rbra__d1l64a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2rbsa__d1j1oy___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2rbtx__d4nvca___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2rbtx__d5ksga1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2rbux__d1atjc___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]; vacuole [GO:0005773]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2rbvx__d1mkqa___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2rbwx__d1mn1a___1	Fungi	Fungi	Ascomycota	Basidiomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]
d2rbwx__d5kqka2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2rbxx__d5sx1b1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2rbzx__d2as1a___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2rc2x__d5sxra2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2rc5a2_d3zc3a2__1			Spirochaetes	Cyanobacteria	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d2rc5b2_d1sm4a2__1		Viridiplantae	Spirochaetes	Streptophyta	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]				chloroplast [GO:0009507]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d2rc5d2_d1bx0a2__1		Viridiplantae	Spirochaetes	Streptophyta	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]		chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	ferredoxin-NADP+ reductase activity [GO:0004324]
d2rc6a2_d1qgab2__1		Viridiplantae	Spirochaetes	Streptophyta	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]		chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	ferredoxin-NADP+ reductase activity [GO:0004324]
d2rc6b2_d1qfzb2__1		Viridiplantae	Spirochaetes	Streptophyta	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]		chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	ferredoxin-NADP+ reductase activity [GO:0004324]
d2rc6c2_d5ue9d2__1			Spirochaetes	Firmicutes	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]
d2rc6d2_d1tvca2__1			Spirochaetes	Proteobacteria	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; one-carbon metabolic process [GO:0006730]		one-carbon metabolic process [GO:0006730]			metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2rcfe__d4n8xm___1			Proteobacteria	Cyanobacteria								
d2rcja1_d4khtl2__1	Metazoa		Chordata			viral envelope [GO:0019031]; structural molecule activity [GO:0005198]				viral envelope [GO:0019031]		structural molecule activity [GO:0005198]
d2rcja2_d4wwkd___1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2rcjb2_d2a9mi___1	Metazoa		Chordata									
d2rcje1_d3okea2__1	Metazoa		Chordata									
d2rcje2_d4l3cb___1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2rcjm2_d4y2dd1__1	Metazoa	Metazoa	Chordata	Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d2rcjn1_d2feco2__1	Metazoa		Chordata	Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d2rcjq2_d3fcta1__1	Metazoa		Chordata									
d2rcjq2_d5m76a2__1	Metazoa		Chordata									
d2rcsh2_d2oz4a3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2rcsl2_d5anma1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2rcta1_d1x71a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d2rcta1_d3wbgd___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]
d2rcua1_d1scza___1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	cytosol [GO:0005829]; oxoglutarate dehydrogenase complex [GO:0045252]; dihydrolipoyllysine-residue succinyltransferase activity [GO:0004149]; lipoic acid binding [GO:0031405]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; tricarboxylic acid cycle [GO:0006099]	fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; oxoglutarate dehydrogenase complex [GO:0045252]	carnitine O-palmitoyltransferase activity [GO:0004095]	dihydrolipoyllysine-residue succinyltransferase activity [GO:0004149]; lipoic acid binding [GO:0031405]
d2rcub1_d1l5ac1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; enterobactin synthetase complex [GO:0009366]; 2,3-dihydroxybenzoate-serine ligase activity [GO:0047527]; acid-ammonia (or amide) ligase activity [GO:0016880]; phosphopantetheine binding [GO:0031177]; amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; enterobactin biosynthetic process [GO:0009239]; secondary metabolite biosynthetic process [GO:0044550]; siderophore biosynthetic process [GO:0019290]	fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]	amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; enterobactin biosynthetic process [GO:0009239]; secondary metabolite biosynthetic process [GO:0044550]; siderophore biosynthetic process [GO:0019290]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; enterobactin synthetase complex [GO:0009366]	carnitine O-palmitoyltransferase activity [GO:0004095]	2,3-dihydroxybenzoate-serine ligase activity [GO:0047527]; acid-ammonia (or amide) ligase activity [GO:0016880]; phosphopantetheine binding [GO:0031177]
d2rcub1_d3maeb___1	Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; carnitine O-palmitoyltransferase activity [GO:0004095]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]		fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid transport [GO:0015909]; positive regulation of cold-induced thermogenesis [GO:0120162]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		carnitine O-palmitoyltransferase activity [GO:0004095]	
d2rcva1_d2bpib1__1			Firmicutes	Apicomplexa	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2rcva2_d4br6b2__1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2rcvb2_d4br6c2__1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2rcve2_d4gunp2__1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2rcvf2_d1my6a2__1			Firmicutes	Cyanobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2rcvg1_d4l2db1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2rcvg2_d2qkca2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2rcwa1_d4rv6b1__1	Metazoa	Metazoa	Chordata	Chordata	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2rd2a2_d3dv2b___1			Proteobacteria		cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]		glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]		cytosol [GO:0005829]		ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]	
d2rd6a2_d1gzfb___1	Metazoa		Chordata		membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	extracellular region [GO:0005576]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	transferase activity, transferring pentosyl groups [GO:0016763]
d2rdbb__d1fz4a___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular aromatic compound metabolic process [GO:0006725]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2rdeb2_d5y4rd___1			Proteobacteria	Proteobacteria	cofactor binding [GO:0048037]; cyclic-di-GMP binding [GO:0035438]	cyclic-di-GMP binding [GO:0035438]; second-messenger-mediated signaling [GO:0019932]		second-messenger-mediated signaling [GO:0019932]			cofactor binding [GO:0048037]; cyclic-di-GMP binding [GO:0035438]	cyclic-di-GMP binding [GO:0035438]
d2rdhc1_d2ntsa1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	pathogenesis [GO:0009405]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2rdhd2_d4o1na2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; peptidase activity [GO:0008233]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		peptidase activity [GO:0008233]
d2rdia1_d2xgpb2__1		Fungi	Crenarchaeota	Ascomycota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d2rdka1_d5k79b___1			Cyanobacteria	Cyanobacteria	carbohydrate binding [GO:0030246]; regulation of defense response to virus [GO:0050688]		regulation of defense response to virus [GO:0050688]				carbohydrate binding [GO:0030246]	
d2rdoe1_d1yj9c1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]	translation [GO:0006412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ribosome [GO:0005840]	ribosomal large subunit binding [GO:0043023]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2rdoi2_d3cjtj2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]	cytoplasm [GO:0005737]; protein methyltransferase activity [GO:0008276]	cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ribosomal large subunit binding [GO:0043023]	protein methyltransferase activity [GO:0008276]
d2rdom1_d2qbim1__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		ribosomal large subunit binding [GO:0043023]	
d2rdov1_d4jyza2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]	glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	ribosomal large subunit binding [GO:0043023]	ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]
d2rdua__d2du2b___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; (S)-2-hydroxy-acid oxidase activity [GO:0003973]; FMN binding [GO:0010181]; glycolate oxidase activity [GO:0008891]; L-lactate dehydrogenase activity [GO:0004459]; long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity [GO:0052853]; medium-chain-(S)-2-hydroxy-acid oxidase activity [GO:0052854]; very-long-chain-(S)-2-hydroxy-acid oxidase activity [GO:0052852]; cellular nitrogen compound metabolic process [GO:0034641]; fatty acid alpha-oxidation [GO:0001561]; glycolate catabolic process [GO:0046296]; lactate oxidation [GO:0019516]; protein targeting to peroxisome [GO:0006625]; response to oxidative stress [GO:0006979]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	cellular nitrogen compound metabolic process [GO:0034641]; fatty acid alpha-oxidation [GO:0001561]; glycolate catabolic process [GO:0046296]; lactate oxidation [GO:0019516]; protein targeting to peroxisome [GO:0006625]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		(S)-2-hydroxy-acid oxidase activity [GO:0003973]; FMN binding [GO:0010181]; glycolate oxidase activity [GO:0008891]; L-lactate dehydrogenase activity [GO:0004459]; long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity [GO:0052853]; medium-chain-(S)-2-hydroxy-acid oxidase activity [GO:0052854]; very-long-chain-(S)-2-hydroxy-acid oxidase activity [GO:0052852]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2rdxb2_d2oneb1__1		Fungi	Proteobacteria	Ascomycota	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2rdxc1_d1mdra2__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]		cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]			metal ion binding [GO:0046872]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d2rdxd2_d5td9a2__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2rdxh2_d1p43a1__1		Fungi	Proteobacteria	Ascomycota	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2rdxh2_d3tjic2__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]		cellular amino acid catabolic process [GO:0009063]			metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]
d2re9b__d1kxgc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cytokine metabolic process [GO:0042107]; immune response [GO:0006955]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cytokine metabolic process [GO:0042107]; immune response [GO:0006955]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]
d2re9c__d5m2mi___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cytokine metabolic process [GO:0042107]; immune response [GO:0006955]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cytokine metabolic process [GO:0042107]; immune response [GO:0006955]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d2reha1_d1rx0a1__1	Fungi	Metazoa	Ascomycota	Chordata	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	mitochondrial matrix [GO:0005759]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; branched-chain amino acid catabolic process [GO:0009083]; lipid metabolic process [GO:0006629]; valine catabolic process [GO:0006574]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	branched-chain amino acid catabolic process [GO:0009083]; lipid metabolic process [GO:0006629]; valine catabolic process [GO:0006574]		mitochondrial matrix [GO:0005759]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d2rehb1_d1ivha1__1	Fungi	Metazoa	Ascomycota	Chordata	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; isovaleryl-CoA dehydrogenase activity [GO:0008470]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552]		mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	flavin adenine dinucleotide binding [GO:0050660]; isovaleryl-CoA dehydrogenase activity [GO:0008470]
d2remb__d1tw9g2__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cell [GO:0005623]; periplasmic space [GO:0042597]; cell redox homeostasis [GO:0045454]	transferase activity [GO:0016740]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]; periplasmic space [GO:0042597]			transferase activity [GO:0016740]
d2remc__d1m99a2__1		Metazoa	Proteobacteria	Platyhelminthes	cell [GO:0005623]; periplasmic space [GO:0042597]; cell redox homeostasis [GO:0045454]	glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]; periplasmic space [GO:0042597]			glutathione transferase activity [GO:0004364]
d2reqa1_d1dioa___1			Actinobacteria	Proteobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	propanediol dehydratase activity [GO:0050215]					cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	propanediol dehydratase activity [GO:0050215]
d2reqa2_d6reqd2__1			Actinobacteria	Actinobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]					cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d2reqd1_d1reqc1__1			Actinobacteria	Actinobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]					cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d2rera1_d3c0vb___1		Viridiplantae	Actinobacteria	Streptophyta	O-methyltransferase activity [GO:0008171]; antibiotic biosynthetic process [GO:0017000]	abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]	antibiotic biosynthetic process [GO:0017000]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]			O-methyltransferase activity [GO:0008171]	abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2rexc__d3r66c1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116]; GTPase activating protein binding [GO:0032794]; GTPase activator activity [GO:0005096]; semaphorin receptor activity [GO:0017154]; semaphorin receptor binding [GO:0030215]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; cell migration [GO:0016477]; G protein-coupled receptor signaling pathway [GO:0007186]; inhibitory synapse assembly [GO:1904862]; intracellular signal transduction [GO:0035556]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cell migration [GO:0016477]; G protein-coupled receptor signaling pathway [GO:0007186]; inhibitory synapse assembly [GO:1904862]; intracellular signal transduction [GO:0035556]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220]; signal transduction [GO:0007165]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	GTPase activating protein binding [GO:0032794]; GTPase activator activity [GO:0005096]; semaphorin receptor activity [GO:0017154]; semaphorin receptor binding [GO:0030215]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2reza2_d2yfia2__1			Actinobacteria	Proteobacteria	O-methyltransferase activity [GO:0008171]; antibiotic biosynthetic process [GO:0017000]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	antibiotic biosynthetic process [GO:0017000]	aromatic compound catabolic process [GO:0019439]			O-methyltransferase activity [GO:0008171]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2rf7d__d4n4ne___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]; anaerobic electron transport chain [GO:0019645]; nitrate assimilation [GO:0042128]		anaerobic electron transport chain [GO:0019645]; nitrate assimilation [GO:0042128]		outer membrane-bounded periplasmic space [GO:0030288]		calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]	
d2rf8b__d5l6bl___1		Fungi	Firmicutes	Ascomycota	choloylglycine hydrolase activity [GO:0045302]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	choloylglycine hydrolase activity [GO:0045302]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2rfgd__d3undd1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]
d2rfha__d2pjab___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d2rfua__d4qy0a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2rfwa__d1v6of___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellulose catabolic process [GO:0030245]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2rfwb__d3d4ka___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cellulose catabolic process [GO:0030245]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2rfwc__d5ocra___1	Fungi		Ascomycota	Bacteroidetes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	kappa-carrageenase activity [GO:0033918]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	kappa-carrageenase activity [GO:0033918]
d2rfya__d1wuva___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]	cellulose catabolic process [GO:0030245]	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]
d2rfyb__d1slbb___1	Fungi	Metazoa	Ascomycota	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]; apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	cellulose catabolic process [GO:0030245]	apoptotic process [GO:0006915]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]		extracellular space [GO:0005615]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]
d2rfyc__d1b09b___1	Fungi	Metazoa	Ascomycota	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cellulose catabolic process [GO:0030245]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d2rfzb__d4v20a___1	Fungi	Fungi	Ascomycota	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d2rfzc__d2ovwc___1	Fungi	Fungi	Ascomycota	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulase activity [GO:0008810]
d2rg0a__d1ul9b___1	Fungi	Fungi	Ascomycota	Basidiomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]	cellulose catabolic process [GO:0030245]			cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]
d2rg0b__d2a3xa___1	Fungi	Metazoa	Ascomycota	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	cellulose catabolic process [GO:0030245]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d2rg0b__d5glva1__1	Fungi	Metazoa	Ascomycota	Nematoda (roundworms)	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]	cellulose catabolic process [GO:0030245]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]
d2rg0d__d5ewso___1	Fungi	Metazoa	Ascomycota	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	cellulose catabolic process [GO:0030245]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2rg7b__d4wesd___1			Proteobacteria	Firmicutes		molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2rg7d__d5lwqa1__1			Proteobacteria	Proteobacteria		metal ion binding [GO:0046872]; iron ion transport [GO:0006826]		iron ion transport [GO:0006826]				metal ion binding [GO:0046872]
d2rg9a__d3menb1__1	Viridiplantae		Streptophyta	Proteobacteria	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	acetylputrescine deacetylase activity [GO:0047609]; metal ion binding [GO:0046872]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]				carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	acetylputrescine deacetylase activity [GO:0047609]; metal ion binding [GO:0046872]
d2rgaa__d1lb1d___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d2rglb__d2f2hd4__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d2rgmb__d1d7fb4__1	Viridiplantae		Streptophyta	Firmicutes	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2rgnc1_d3kqub2__1	Metazoa		Chordata		caveola [GO:0005901]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; alkylglycerophosphoethanolamine phosphodiesterase activity [GO:0047391]; G protein-coupled receptor binding [GO:0001664]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTP binding [GO:0005525]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; type 2A serotonin receptor binding [GO:0031826]; action potential [GO:0001508]; activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; developmental pigmentation [GO:0048066]; embryonic digit morphogenesis [GO:0042733]; forebrain neuron development [GO:0021884]; G protein-coupled receptor signaling pathway [GO:0007186]; glutamate receptor signaling pathway [GO:0007215]; heart development [GO:0007507]; maternal behavior [GO:0042711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein kinase activity [GO:0006469]; neuron remodeling [GO:0016322]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of smooth muscle cell proliferation [GO:0048661]; post-embryonic development [GO:0009791]; protein stabilization [GO:0050821]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of melanocyte differentiation [GO:0045634]; skeletal system development [GO:0001501]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	action potential [GO:0001508]; activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; developmental pigmentation [GO:0048066]; embryonic digit morphogenesis [GO:0042733]; forebrain neuron development [GO:0021884]; glutamate receptor signaling pathway [GO:0007215]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; maternal behavior [GO:0042711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of protein kinase activity [GO:0006469]; neuron remodeling [GO:0016322]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of smooth muscle cell proliferation [GO:0048661]; post-embryonic development [GO:0009791]; protein stabilization [GO:0050821]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of melanocyte differentiation [GO:0045634]; skeletal system development [GO:0001501]	actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	caveola [GO:0005901]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	alkylglycerophosphoethanolamine phosphodiesterase activity [GO:0047391]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; type 2A serotonin receptor binding [GO:0031826]	actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2rgsa2_d3miqg___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2rgwc2_d2ef0a1__1			Euryarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d2rgwc2_d2qgfa2__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2rgwd2_d1raea1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2rgwf2_d3d7sa2__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d2rgza__d1wnva___1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	heme oxidation [GO:0006788]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]		heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d2rgzb__d3i8ra___1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	heme oxidation [GO:0006788]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]		heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d2rhbc1_d2gtha1__1					cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]
d2rhra__d3r3jd2__1			Actinobacteria	Apicomplexa	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]	apicoplast [GO:0020011]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]; cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	antibiotic biosynthetic process [GO:0017000]	cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]		apicoplast [GO:0020011]; cytosol [GO:0005829]	oxidoreductase activity [GO:0016491]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]
d2rhsc1_d1adjc2__1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	phenylalanyl-tRNA aminoacylation [GO:0006432]	histidyl-tRNA aminoacylation [GO:0006427]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]
d2rhwa__d2d0da___1			Proteobacteria	Proteobacteria	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; aromatic compound catabolic process [GO:0019439]	hydrolase activity [GO:0016787]	aromatic compound catabolic process [GO:0019439]				2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]	hydrolase activity [GO:0016787]
d2ri4b__d1gh0i___1	Metazoa		Chordata	Cyanobacteria	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2ri4d__d1y7zd___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2riaa1_d4m17j___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d2riba1_d5bzsa___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d2rica1_d3wwki___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	regulation of cytokine activity [GO:0060300]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d2ricb1_d1kwzc1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d2rida1_d3bdwa___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; carbohydrate binding [GO:0030246]; MHC class I protein complex binding [GO:0023024]; MHC class Ib protein binding, via antigen binding groove [GO:0023030]; protein antigen binding [GO:1990405]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; natural killer cell mediated immunity [GO:0002228]; regulation of immune response [GO:0050776]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; natural killer cell mediated immunity [GO:0002228]; regulation of immune response [GO:0050776]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; MHC class Ib protein binding, via antigen binding groove [GO:0023030]; MHC class I protein complex binding [GO:0023024]; protein antigen binding [GO:1990405]; transmembrane signaling receptor activity [GO:0004888]
d2riea1_d1kwwb1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d2rieb1_d1kwva1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d2riha__d2uv7a1__1		Metazoa	Crenarchaeota	Chordata	nucleotide binding [GO:0000166]	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; ADP binding [GO:0043531]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; cAMP-dependent protein kinase activity [GO:0004691]; cAMP-dependent protein kinase regulator activity [GO:0008603]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; cell cycle arrest [GO:0007050]; fatty acid biosynthetic process [GO:0006633]; import into nucleus [GO:0051170]; macroautophagy [GO:0016236]; positive regulation of gene expression [GO:0010628]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]; regulation of glycolytic process [GO:0006110]; regulation of macroautophagy [GO:0016241]; regulation of signal transduction by p53 class mediator [GO:1901796]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]		cell cycle arrest [GO:0007050]; fatty acid biosynthetic process [GO:0006633]; import into nucleus [GO:0051170]; macroautophagy [GO:0016236]; positive regulation of gene expression [GO:0010628]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]; regulation of glycolytic process [GO:0006110]; regulation of macroautophagy [GO:0016241]; regulation of signal transduction by p53 class mediator [GO:1901796]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]		cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]	nucleotide binding [GO:0000166]	ADP binding [GO:0043531]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; cAMP-dependent protein kinase activity [GO:0004691]; cAMP-dependent protein kinase regulator activity [GO:0008603]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]
d2rika2_d1oaxj___1	Metazoa	Metazoa	Chordata	Chordata	telethonin binding [GO:0031433]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	telethonin binding [GO:0031433]	
d2riza1_d1iima___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]		antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]
d2rj2a1_d1umia1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; organelle membrane [GO:0031090]; SCF ubiquitin ligase complex [GO:0019005]; amyloid-beta binding [GO:0001540]; carbohydrate binding [GO:0030246]; glycoprotein catabolic process [GO:0006516]; negative regulation of cell population proliferation [GO:0008285]; protein ubiquitination [GO:0016567]; regulation of protein ubiquitination [GO:0031396]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; organelle membrane [GO:0031090]; SCF ubiquitin ligase complex [GO:0019005]; amyloid-beta binding [GO:0001540]; carbohydrate binding [GO:0030246]; glycoprotein catabolic process [GO:0006516]; negative regulation of cell population proliferation [GO:0008285]; protein ubiquitination [GO:0016567]; regulation of protein ubiquitination [GO:0031396]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	glycoprotein catabolic process [GO:0006516]; negative regulation of cell population proliferation [GO:0008285]; protein ubiquitination [GO:0016567]; regulation of protein ubiquitination [GO:0031396]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	glycoprotein catabolic process [GO:0006516]; negative regulation of cell population proliferation [GO:0008285]; protein ubiquitination [GO:0016567]; regulation of protein ubiquitination [GO:0031396]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; organelle membrane [GO:0031090]; SCF ubiquitin ligase complex [GO:0019005]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; organelle membrane [GO:0031090]; SCF ubiquitin ligase complex [GO:0019005]	amyloid-beta binding [GO:0001540]; carbohydrate binding [GO:0030246]	amyloid-beta binding [GO:0001540]; carbohydrate binding [GO:0030246]
d2rj2a1_d3hnym___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; organelle membrane [GO:0031090]; SCF ubiquitin ligase complex [GO:0019005]; amyloid-beta binding [GO:0001540]; carbohydrate binding [GO:0030246]; glycoprotein catabolic process [GO:0006516]; negative regulation of cell population proliferation [GO:0008285]; protein ubiquitination [GO:0016567]; regulation of protein ubiquitination [GO:0031396]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	glycoprotein catabolic process [GO:0006516]; negative regulation of cell population proliferation [GO:0008285]; protein ubiquitination [GO:0016567]; regulation of protein ubiquitination [GO:0031396]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; organelle membrane [GO:0031090]; SCF ubiquitin ligase complex [GO:0019005]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	amyloid-beta binding [GO:0001540]; carbohydrate binding [GO:0030246]	copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]
d2rjcb1_d2r58a2__1	Metazoa	Metazoa	Chordata	Arthropoda	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]; chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	nucleus [GO:0005634]; polytene chromosome [GO:0005700]; PRC1 complex [GO:0035102]; identical protein binding [GO:0042802]; PRC1 complex binding [GO:0140259]; zinc ion binding [GO:0008270]; axonogenesis [GO:0007409]; chromatin organization [GO:0006325]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; ventral cord development [GO:0007419]	chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	axonogenesis [GO:0007409]; chromatin organization [GO:0006325]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; ventral cord development [GO:0007419]	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	nucleus [GO:0005634]; polytene chromosome [GO:0005700]; PRC1 complex [GO:0035102]	chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; PRC1 complex binding [GO:0140259]; zinc ion binding [GO:0008270]
d2rjma1_d5wlge1__1	Metazoa	Metazoa	Chordata	Chordata	telethonin binding [GO:0031433]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	telethonin binding [GO:0031433]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2rjma2_d2bvea___1	Metazoa	Metazoa	Chordata	Chordata	telethonin binding [GO:0031433]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]		cell adhesion [GO:0007155]; endocytosis [GO:0006897]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell apoptotic process [GO:0070234]		extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	telethonin binding [GO:0031433]	carbohydrate binding [GO:0030246]
d2rjma3_d2cjuh___1	Metazoa	Metazoa	Chordata	Chordata	telethonin binding [GO:0031433]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	telethonin binding [GO:0031433]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2rjta1_d1wdkc1__1			Firmicutes	Proteobacteria	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation multienzyme complex [GO:0036125]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d2rjta2_d2vb8b2__1			Firmicutes	Proteobacteria	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2rjtb1_d1h4fa2__1			Firmicutes	Proteobacteria	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2rjtd1_d1ulqh1__1			Firmicutes	Deinococcus-Thermus	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	fatty acid biosynthetic process [GO:0006633]				beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2rjtd2_d2efta1__1			Firmicutes	Proteobacteria	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		cytosol [GO:0005829]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2rjva__d1yu8x___1	Metazoa	Metazoa	Chordata	Chordata	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]
d2rjxa__d2k6ms1__1	Metazoa	Metazoa	Chordata	Chordata	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	actin cytoskeleton [GO:0015629]; cleavage furrow [GO:0032154]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; invadopodium [GO:0071437]; microtubule minus-end [GO:0036449]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; podosome [GO:0002102]; actin filament binding [GO:0051015]; cytoskeleton organization [GO:0007010]; positive regulation of cytokinesis [GO:0032467]; skeletal muscle tissue development [GO:0007519]	actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	cytoskeleton organization [GO:0007010]; positive regulation of cytokinesis [GO:0032467]; skeletal muscle tissue development [GO:0007519]	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]	actin cytoskeleton [GO:0015629]; cleavage furrow [GO:0032154]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; invadopodium [GO:0071437]; microtubule minus-end [GO:0036449]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; podosome [GO:0002102]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]
d2rk3a__d3czaa___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]
d2rk7a1_d2zcib1__1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; gluconeogenesis [GO:0006094]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	gluconeogenesis [GO:0006094]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]	GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]
d2rkaa1_d4wpta1__1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; gluconeogenesis [GO:0006094]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	gluconeogenesis [GO:0006094]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]	GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]
d2rkbd__d3vc3d___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; pyridoxal phosphate binding [GO:0030170]; L-serine catabolic process [GO:0006565]; L-threonine catabolic process to glycine [GO:0019518]; threonine catabolic process [GO:0006567]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]; cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	L-serine catabolic process [GO:0006565]; L-threonine catabolic process to glycine [GO:0019518]; threonine catabolic process [GO:0006567]	cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; pyridoxal phosphate binding [GO:0030170]	cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]
d2rkfb__d3cicb___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d2rkia3_d5cy4f___1				Proteobacteria	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; 3'-5'-exoribonuclease activity [GO:0000175]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2rksa__d3shla___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2rkwb3_d2jj1h3__1		Metazoa	Euryarchaeota	Chordata	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2rl9b__d2l29a1__1	Metazoa	Metazoa	Chordata	Chordata	endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]; protein domain specific binding [GO:0019904]; retromer complex binding [GO:1905394]; lysosomal transport [GO:0007041]; protein targeting to lysosome [GO:0006622]; secretion of lysosomal enzymes [GO:0033299]	cell surface [GO:0009986]; clathrin coat [GO:0030118]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; trans-Golgi network transport vesicle [GO:0030140]; transport vesicle [GO:0030133]; enzyme binding [GO:0019899]; G-protein alpha-subunit binding [GO:0001965]; identical protein binding [GO:0042802]; insulin-like growth factor binding [GO:0005520]; insulin-like growth factor II binding [GO:0031995]; insulin-like growth factor-activated receptor activity [GO:0005010]; mannose binding [GO:0005537]; phosphoprotein binding [GO:0051219]; retinoic acid binding [GO:0001972]; signaling receptor activity [GO:0038023]; animal organ regeneration [GO:0031100]; G protein-coupled receptor signaling pathway [GO:0007186]; liver development [GO:0001889]; lysosomal transport [GO:0007041]; membrane organization [GO:0061024]; neutrophil degranulation [GO:0043312]; positive regulation by host of viral process [GO:0044794]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; receptor-mediated endocytosis [GO:0006898]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]	lysosomal transport [GO:0007041]; protein targeting to lysosome [GO:0006622]; secretion of lysosomal enzymes [GO:0033299]	animal organ regeneration [GO:0031100]; G protein-coupled receptor signaling pathway [GO:0007186]; liver development [GO:0001889]; lysosomal transport [GO:0007041]; membrane organization [GO:0061024]; neutrophil degranulation [GO:0043312]; positive regulation by host of viral process [GO:0044794]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; receptor-mediated endocytosis [GO:0006898]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]	endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]	cell surface [GO:0009986]; clathrin coat [GO:0030118]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; trans-Golgi network transport vesicle [GO:0030140]; transport vesicle [GO:0030133]	protein domain specific binding [GO:0019904]; retromer complex binding [GO:1905394]	enzyme binding [GO:0019899]; G-protein alpha-subunit binding [GO:0001965]; identical protein binding [GO:0042802]; insulin-like growth factor-activated receptor activity [GO:0005010]; insulin-like growth factor binding [GO:0005520]; insulin-like growth factor II binding [GO:0031995]; mannose binding [GO:0005537]; phosphoprotein binding [GO:0051219]; retinoic acid binding [GO:0001972]; signaling receptor activity [GO:0038023]
d2rlab__d2v5wb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]
d2rlac__d4qa0b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]
d2rlac__d5rlaa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d2rlia1_d4n11a___1	Metazoa		Chordata	Apicomplexa	cell [GO:0005623]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; copper ion binding [GO:0005507]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; eye development [GO:0001654]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; antioxidant activity [GO:0016209]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase (glutathione) activity [GO:0019153]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; eye development [GO:0001654]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; myofibril [GO:0030016]	cell [GO:0005623]	copper ion binding [GO:0005507]; protein disulfide oxidoreductase activity [GO:0015035]	antioxidant activity [GO:0016209]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase (glutathione) activity [GO:0019153]
d2rlzb1_d2lrld___1			Firmicutes	Proteobacteria		cytosol [GO:0005829]; protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity [GO:0090566]; N,N'-diacetylchitobiose import [GO:1902815]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; protein homooligomerization [GO:0051260]		N,N'-diacetylchitobiose import [GO:1902815]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; protein homooligomerization [GO:0051260]		cytosol [GO:0005829]		protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity [GO:0090566]
d2rlzb1_d3le3b___1			Firmicutes	Firmicutes		cytoplasm [GO:0005737]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]		phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]		cytoplasm [GO:0005737]		transferase activity [GO:0016740]
d2rm23__d4y5zo___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d2rm5a1_d2vm1b___1		Viridiplantae		Streptophyta	glycosome [GO:0020015]; glutathione peroxidase activity [GO:0004602]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	glycosome [GO:0020015]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]	protein disulfide oxidoreductase activity [GO:0015035]
d2rmam__d2phcb1__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]		entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	
d2rmao__d4j5cx___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]
d2rmbs__d4o8ha___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]
d2rmcg__d2he9a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]	plasma membrane [GO:0005886]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]	protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]	protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]	cytoplasm [GO:0005737]	plasma membrane [GO:0005886]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]
d2rmkb2_d1cxzb___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; histone deacetylase binding [GO:0042826]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]; actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cell-matrix adhesion [GO:0007160]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure morphogenesis [GO:0009653]; blood coagulation [GO:0007596]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cellular response to mechanical stimulus [GO:0071260]; engulfment of apoptotic cell [GO:0043652]; ephrin receptor signaling pathway [GO:0048013]; establishment or maintenance of cell polarity [GO:0007163]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; motor neuron axon guidance [GO:0008045]; negative regulation of interleukin-23 production [GO:0032707]; negative regulation of receptor-mediated endocytosis [GO:0048261]; neuron migration [GO:0001764]; neutrophil degranulation [GO:0043312]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of defense response to virus by virus [GO:0050690]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of lamellipodium assembly [GO:0010591]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; recycling endosome membrane [GO:0055038]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	ATPase binding [GO:0051117]; enzyme binding [GO:0019899]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; histone deacetylase binding [GO:0042826]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; Rho GDP-dissociation inhibitor binding [GO:0051022]; thioesterase binding [GO:0031996]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d2rnrb__d2jp2a1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]; chromatin binding [GO:0003682]; 7-methylguanosine mRNA capping [GO:0006370]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase I promoter [GO:0006361]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription-coupled nucleotide-excision repair [GO:0006283]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; transport vesicle membrane [GO:0030658]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; stem cell factor receptor binding [GO:0005173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inactivation of MAPK activity [GO:0000188]; multicellular organism development [GO:0007275]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; regulation of protein deacetylation [GO:0090311]	7-methylguanosine mRNA capping [GO:0006370]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]	fibroblast growth factor receptor signaling pathway [GO:0008543]; inactivation of MAPK activity [GO:0000188]; multicellular organism development [GO:0007275]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; regulation of protein deacetylation [GO:0090311]	nucleoplasm [GO:0005654]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; transport vesicle membrane [GO:0030658]	chromatin binding [GO:0003682]	protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; stem cell factor receptor binding [GO:0005173]
d2rnta__d1rgfb___1	Fungi		Ascomycota	Actinobacteria	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d2rnwa2_d2ydwc___1	Metazoa	Metazoa	Chordata	Chordata	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]
d2ro8a__d1b8ca___1	Viridiplantae	Metazoa	Streptophyta	Chordata	calcium ion binding [GO:0005509]; calcium-mediated signaling [GO:0019722]	calcium ion binding [GO:0005509]	calcium-mediated signaling [GO:0019722]				calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]
d2roaa__d1wlzd___1	Viridiplantae	Metazoa	Streptophyta	Chordata	calcium ion binding [GO:0005509]; calcium-mediated signaling [GO:0019722]	nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]	calcium-mediated signaling [GO:0019722]			nucleoplasm [GO:0005654]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]
d2roba__d1cmfa___1	Viridiplantae	Metazoa	Streptophyta	Chordata	calcium ion binding [GO:0005509]; calcium-mediated signaling [GO:0019722]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]; calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]; calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	calcium-mediated signaling [GO:0019722]	calcium-mediated signaling [GO:0019722]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; spindle pole [GO:0000922]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; protein domain specific binding [GO:0019904]
d2roka1_d2dgqa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; 3'-5'-exoribonuclease activity [GO:0000175]; cation binding [GO:0043169]; metal ion binding [GO:0046872]; poly(A)-specific ribonuclease activity [GO:0004535]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; box H/ACA snoRNA 3'-end processing [GO:0000495]; miRNA catabolic process [GO:0010587]; ncRNA deadenylation [GO:0110008]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of telomerase RNA localization to Cajal body [GO:1904872]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; telomerase RNA stabilization [GO:0090669]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	box H/ACA snoRNA 3'-end processing [GO:0000495]; miRNA catabolic process [GO:0010587]; ncRNA deadenylation [GO:0110008]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of telomerase RNA localization to Cajal body [GO:1904872]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; telomerase RNA stabilization [GO:0090669]	mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	3'-5'-exoribonuclease activity [GO:0000175]; cation binding [GO:0043169]; metal ion binding [GO:0046872]; poly(A)-specific ribonuclease activity [GO:0004535]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d2rr11__d1tme1___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host mRNA export from nucleus [GO:0039522]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host mRNA export from nucleus [GO:0039522]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2rr11__d1yc6s___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2rr13__d1ev13___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2rr13__d4y5z6___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d2rr8a1_d1aa2a___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; midbody [GO:0030496]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; ruffle [GO:0001726]; secretory granule membrane [GO:0030667]; slit diaphragm [GO:0036057]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; GTPase inhibitor activity [GO:0005095]; mitogen-activated protein kinase binding [GO:0051019]; molecular adaptor activity [GO:0060090]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine kinase activator activity [GO:0043539]; protein-containing complex binding [GO:0044877]; Rac GTPase binding [GO:0048365]; S100 protein binding [GO:0044548]; small GTPase binding [GO:0031267]; cell migration [GO:0016477]; cellular response to calcium ion [GO:0071277]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glomerular visceral epithelial cell development [GO:0072015]; negative regulation of dephosphorylation [GO:0035305]; neuron projection extension [GO:1990138]; neutrophil degranulation [GO:0043312]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cellular protein localization [GO:1903829]; positive regulation of dendrite development [GO:1900006]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; regulation of cytokine production [GO:0001817]; regulation of mitotic cell cycle [GO:0007346]; response to angiotensin [GO:1990776]; signal transduction [GO:0007165]; viral process [GO:0016032]	axolemma [GO:0030673]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; nucleolus [GO:0005730]; postsynaptic density [GO:0014069]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390]	cell migration [GO:0016477]; cellular response to calcium ion [GO:0071277]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glomerular visceral epithelial cell development [GO:0072015]; negative regulation of dephosphorylation [GO:0035305]; neuron projection extension [GO:1990138]; neutrophil degranulation [GO:0043312]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cellular protein localization [GO:1903829]; positive regulation of dendrite development [GO:1900006]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; regulation of cytokine production [GO:0001817]; regulation of mitotic cell cycle [GO:0007346]; response to angiotensin [GO:1990776]; signal transduction [GO:0007165]; viral process [GO:0016032]	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390]	actin filament [GO:0005884]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; midbody [GO:0030496]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; ruffle [GO:0001726]; secretory granule membrane [GO:0030667]; slit diaphragm [GO:0036057]	axolemma [GO:0030673]; cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; M band [GO:0031430]; nucleolus [GO:0005730]; postsynaptic density [GO:0014069]; spectrin [GO:0008091]; spectrin-associated cytoskeleton [GO:0014731]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; GTPase inhibitor activity [GO:0005095]; mitogen-activated protein kinase binding [GO:0051019]; molecular adaptor activity [GO:0060090]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine kinase activator activity [GO:0043539]; Rac GTPase binding [GO:0048365]; S100 protein binding [GO:0044548]; small GTPase binding [GO:0031267]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; GTPase binding [GO:0051020]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]
d2rr9b__d2bweu___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; nucleus [GO:0005634]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein binding, bridging [GO:0030674]; protein localization to vacuole [GO:0072665]; spindle pole body duplication [GO:0030474]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	protein localization to vacuole [GO:0072665]; spindle pole body duplication [GO:0030474]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytosol [GO:0005829]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	polyubiquitin modification-dependent protein binding [GO:0031593]; protein binding, bridging [GO:0030674]
d2rs11__d1yc6h___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2rs13__d1ncqa___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2rs13__d5fmol2__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]; DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; transport of virus in host, cell to cell [GO:0046740]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	transport of virus in host, cell to cell [GO:0046740]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell nucleus [GO:0042025]; host cell plasmodesma [GO:0044219]; T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; GTP binding [GO:0005525]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2rs5.1_d3cjib___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=3 icosahedral viral capsid [GO:0039617]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; Lys48-specific deubiquitinase activity [GO:1990380]; Lys63-specific deubiquitinase activity [GO:0061578]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host RIG-I signaling pathway [GO:0039538]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host TRAF activity [GO:0039547]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host RIG-I signaling pathway [GO:0039538]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host TRAF activity [GO:0039547]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=3 icosahedral viral capsid [GO:0039617]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; Lys48-specific deubiquitinase activity [GO:1990380]; Lys63-specific deubiquitinase activity [GO:0061578]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]
d2rs51__d4y5ze___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d2rs8a1_d1oo0b___1	Metazoa	Metazoa	Chordata	Arthropoda	fibrillar center [GO:0001650]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; RNA polymerase II transcription factor complex [GO:0090575]; chromatin binding [GO:0003682]; E-box binding [GO:0070888]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; activation of innate immune response [GO:0002218]; circadian rhythm [GO:0007623]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of circadian rhythm [GO:0042752]; RNA splicing [GO:0008380]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; exon-exon junction complex [GO:0035145]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; establishment of pole plasm mRNA localization [GO:0046595]; germarium-derived oocyte fate determination [GO:0007294]; microtubule cytoskeleton organization [GO:0000226]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of transposition, DNA-mediated [GO:0000335]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte dorsal/ventral axis specification [GO:0007310]; oocyte nucleus localization involved in oocyte dorsal/ventral axis specification [GO:0051663]; pole plasm oskar mRNA localization [GO:0045451]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of pole plasm oskar mRNA localization [GO:0007317]; RNA splicing [GO:0008380]	activation of innate immune response [GO:0002218]; circadian rhythm [GO:0007623]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of circadian rhythm [GO:0042752]; RNA splicing [GO:0008380]	establishment of pole plasm mRNA localization [GO:0046595]; germarium-derived oocyte fate determination [GO:0007294]; microtubule cytoskeleton organization [GO:0000226]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of transposition, DNA-mediated [GO:0000335]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte dorsal/ventral axis specification [GO:0007310]; oocyte nucleus localization involved in oocyte dorsal/ventral axis specification [GO:0051663]; pole plasm oskar mRNA localization [GO:0045451]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of pole plasm oskar mRNA localization [GO:0007317]; RNA splicing [GO:0008380]	fibrillar center [GO:0001650]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; RNA polymerase II transcription factor complex [GO:0090575]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; exon-exon junction complex [GO:0035145]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; E-box binding [GO:0070888]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	mRNA binding [GO:0003729]
d2rs8a1_d2dgpa1__1	Metazoa	Metazoa	Chordata	Chordata	fibrillar center [GO:0001650]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; RNA polymerase II transcription factor complex [GO:0090575]; chromatin binding [GO:0003682]; E-box binding [GO:0070888]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; activation of innate immune response [GO:0002218]; circadian rhythm [GO:0007623]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of circadian rhythm [GO:0042752]; RNA splicing [GO:0008380]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; BRE binding [GO:0042835]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; alternative mRNA splicing, via spliceosome [GO:0000380]; embryo development ending in birth or egg hatching [GO:0009792]; germ cell development [GO:0007281]; in utero embryonic development [GO:0001701]; mRNA splice site selection [GO:0006376]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of retina development in camera-type eye [GO:1902866]	activation of innate immune response [GO:0002218]; circadian rhythm [GO:0007623]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of circadian rhythm [GO:0042752]; RNA splicing [GO:0008380]	alternative mRNA splicing, via spliceosome [GO:0000380]; embryo development ending in birth or egg hatching [GO:0009792]; germ cell development [GO:0007281]; in utero embryonic development [GO:0001701]; mRNA splice site selection [GO:0006376]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of retina development in camera-type eye [GO:1902866]	fibrillar center [GO:0001650]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; RNA polymerase II transcription factor complex [GO:0090575]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	chromatin binding [GO:0003682]; E-box binding [GO:0070888]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	BRE binding [GO:0042835]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d2rslc__d3pkzc___1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]; transposition [GO:0032196]	DNA integration [GO:0015074]	DNA integration [GO:0015074]; transposition [GO:0032196]			DNA binding [GO:0003677]; recombinase activity [GO:0000150]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]
d2rtcb__d4z27a___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]
d2rteb__d5f2ba1__1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2rtfb__d3t2xc___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2rtua1_d1nhma___1	Metazoa	Metazoa	Chordata	Chordata	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; cell [GO:0005623]; cell surface [GO:0009986]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; transcriptional repressor complex [GO:0017053]; bubble DNA binding [GO:0000405]; C-X-C chemokine binding [GO:0019958]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA polymerase binding [GO:0070182]; double-stranded DNA binding [GO:0003690]; four-way junction DNA binding [GO:0000400]; integrin binding [GO:0005178]; lipopolysaccharide binding [GO:0001530]; lyase activity [GO:0016829]; phosphatidylserine binding [GO:0001786]; RAGE receptor binding [GO:0050786]; repressing transcription factor binding [GO:0070491]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of innate immune response [GO:0002218]; apoptotic cell clearance [GO:0043277]; apoptotic DNA fragmentation [GO:0006309]; autophagy [GO:0006914]; cell chemotaxis [GO:0060326]; cellular response to lipopolysaccharide [GO:0071222]; chromatin silencing [GO:0006342]; dendritic cell chemotaxis [GO:0002407]; developmental process [GO:0032502]; DNA geometric change [GO:0032392]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA topological change [GO:0006265]; inflammatory response [GO:0006954]; inflammatory response to antigenic stimulus [GO:0002437]; innate immune response [GO:0045087]; myeloid dendritic cell activation [GO:0001773]; negative regulation of apoptotic cell clearance [GO:2000426]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0017055]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron projection development [GO:0031175]; neutrophil clearance [GO:0097350]; neutrophil degranulation [GO:0043312]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA ligation [GO:0051106]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-1 secretion [GO:0050716]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mismatch repair [GO:0032425]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; regulation of restriction endodeoxyribonuclease activity [GO:0032072]; regulation of signaling receptor activity [GO:0010469]; regulation of T cell mediated immune response to tumor cell [GO:0002840]; regulation of tolerance induction [GO:0002643]; regulation of transcription by RNA polymerase II [GO:0006357]; T-helper 1 cell activation [GO:0035711]; T-helper 1 cell differentiation [GO:0045063]; toll-like receptor signaling pathway [GO:0002224]; tumor necrosis factor secretion [GO:1990774]; V(D)J recombination [GO:0033151]	condensed chromosome [GO:0000793]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; DNA binding [GO:0003677]; adaptive immune response [GO:0002250]; apoptotic cell clearance [GO:0043277]; autophagy [GO:0006914]; chemotaxis [GO:0006935]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0017055]; neutrophil clearance [GO:0097350]; positive regulation of DNA ligation [GO:0051106]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; regulation of T cell mediated immune response to tumor cell [GO:0002840]	activation of innate immune response [GO:0002218]; apoptotic cell clearance [GO:0043277]; apoptotic DNA fragmentation [GO:0006309]; autophagy [GO:0006914]; cell chemotaxis [GO:0060326]; cellular response to lipopolysaccharide [GO:0071222]; chromatin silencing [GO:0006342]; dendritic cell chemotaxis [GO:0002407]; developmental process [GO:0032502]; DNA geometric change [GO:0032392]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA topological change [GO:0006265]; inflammatory response [GO:0006954]; inflammatory response to antigenic stimulus [GO:0002437]; innate immune response [GO:0045087]; myeloid dendritic cell activation [GO:0001773]; negative regulation of apoptotic cell clearance [GO:2000426]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0017055]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron projection development [GO:0031175]; neutrophil clearance [GO:0097350]; neutrophil degranulation [GO:0043312]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA ligation [GO:0051106]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-1 secretion [GO:0050716]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mismatch repair [GO:0032425]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; regulation of restriction endodeoxyribonuclease activity [GO:0032072]; regulation of signaling receptor activity [GO:0010469]; regulation of T cell mediated immune response to tumor cell [GO:0002840]; regulation of tolerance induction [GO:0002643]; regulation of transcription by RNA polymerase II [GO:0006357]; T-helper 1 cell activation [GO:0035711]; T-helper 1 cell differentiation [GO:0045063]; toll-like receptor signaling pathway [GO:0002224]; tumor necrosis factor secretion [GO:1990774]; V(D)J recombination [GO:0033151]	adaptive immune response [GO:0002250]; apoptotic cell clearance [GO:0043277]; autophagy [GO:0006914]; chemotaxis [GO:0006935]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0017055]; neutrophil clearance [GO:0097350]; positive regulation of DNA ligation [GO:0051106]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; regulation of T cell mediated immune response to tumor cell [GO:0002840]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; cell [GO:0005623]; cell surface [GO:0009986]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; transcriptional repressor complex [GO:0017053]	condensed chromosome [GO:0000793]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	bubble DNA binding [GO:0000405]; chemoattractant activity [GO:0042056]; C-X-C chemokine binding [GO:0019958]; cytokine activity [GO:0005125]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA polymerase binding [GO:0070182]; double-stranded DNA binding [GO:0003690]; four-way junction DNA binding [GO:0000400]; integrin binding [GO:0005178]; lipopolysaccharide binding [GO:0001530]; lyase activity [GO:0016829]; phosphatidylserine binding [GO:0001786]; RAGE receptor binding [GO:0050786]; repressing transcription factor binding [GO:0070491]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	DNA binding [GO:0003677]
d2rtua1_d4a3na___1	Metazoa	Metazoa	Chordata	Chordata	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; cell [GO:0005623]; cell surface [GO:0009986]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; transcriptional repressor complex [GO:0017053]; bubble DNA binding [GO:0000405]; C-X-C chemokine binding [GO:0019958]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA polymerase binding [GO:0070182]; double-stranded DNA binding [GO:0003690]; four-way junction DNA binding [GO:0000400]; integrin binding [GO:0005178]; lipopolysaccharide binding [GO:0001530]; lyase activity [GO:0016829]; phosphatidylserine binding [GO:0001786]; RAGE receptor binding [GO:0050786]; repressing transcription factor binding [GO:0070491]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of innate immune response [GO:0002218]; apoptotic cell clearance [GO:0043277]; apoptotic DNA fragmentation [GO:0006309]; autophagy [GO:0006914]; cell chemotaxis [GO:0060326]; cellular response to lipopolysaccharide [GO:0071222]; chromatin silencing [GO:0006342]; dendritic cell chemotaxis [GO:0002407]; developmental process [GO:0032502]; DNA geometric change [GO:0032392]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA topological change [GO:0006265]; inflammatory response [GO:0006954]; inflammatory response to antigenic stimulus [GO:0002437]; innate immune response [GO:0045087]; myeloid dendritic cell activation [GO:0001773]; negative regulation of apoptotic cell clearance [GO:2000426]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0017055]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron projection development [GO:0031175]; neutrophil clearance [GO:0097350]; neutrophil degranulation [GO:0043312]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA ligation [GO:0051106]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-1 secretion [GO:0050716]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mismatch repair [GO:0032425]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; regulation of restriction endodeoxyribonuclease activity [GO:0032072]; regulation of signaling receptor activity [GO:0010469]; regulation of T cell mediated immune response to tumor cell [GO:0002840]; regulation of tolerance induction [GO:0002643]; regulation of transcription by RNA polymerase II [GO:0006357]; T-helper 1 cell activation [GO:0035711]; T-helper 1 cell differentiation [GO:0045063]; toll-like receptor signaling pathway [GO:0002224]; tumor necrosis factor secretion [GO:1990774]; V(D)J recombination [GO:0033151]	nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; beta-catenin binding [GO:0008013]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; angiogenesis [GO:0001525]; cardiac cell fate determination [GO:0060913]; cardiogenic plate morphogenesis [GO:0003142]; cell differentiation [GO:0030154]; cell migration involved in gastrulation [GO:0042074]; cellular response to leukemia inhibitory factor [GO:1990830]; common bile duct development [GO:0061009]; embryonic foregut morphogenesis [GO:0048617]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; endocardial cell differentiation [GO:0060956]; endocardium formation [GO:0060214]; endoderm formation [GO:0001706]; endodermal cell fate determination [GO:0007493]; endodermal digestive tract morphogenesis [GO:0061031]; gall bladder development [GO:0061010]; heart formation [GO:0060914]; heart looping [GO:0001947]; inner cell mass cellular morphogenesis [GO:0001828]; metanephros development [GO:0001656]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; outflow tract morphogenesis [GO:0003151]; positive regulation of cell differentiation [GO:0045597]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; regulation of cardiac cell fate specification [GO:2000043]; regulation of embryonic development [GO:0045995]; regulation of stem cell division [GO:2000035]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification [GO:0060807]; regulation of transcription, DNA-templated [GO:0006355]; rostrocaudal neural tube patterning [GO:0021903]; signal transduction involved in regulation of gene expression [GO:0023019]; spermatogenesis [GO:0007283]; stem cell fate specification [GO:0048866]; ureter development [GO:0072189]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055]	activation of innate immune response [GO:0002218]; apoptotic cell clearance [GO:0043277]; apoptotic DNA fragmentation [GO:0006309]; autophagy [GO:0006914]; cell chemotaxis [GO:0060326]; cellular response to lipopolysaccharide [GO:0071222]; chromatin silencing [GO:0006342]; dendritic cell chemotaxis [GO:0002407]; developmental process [GO:0032502]; DNA geometric change [GO:0032392]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA topological change [GO:0006265]; inflammatory response [GO:0006954]; inflammatory response to antigenic stimulus [GO:0002437]; innate immune response [GO:0045087]; myeloid dendritic cell activation [GO:0001773]; negative regulation of apoptotic cell clearance [GO:2000426]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0017055]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron projection development [GO:0031175]; neutrophil clearance [GO:0097350]; neutrophil degranulation [GO:0043312]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA ligation [GO:0051106]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-1 secretion [GO:0050716]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mismatch repair [GO:0032425]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; regulation of restriction endodeoxyribonuclease activity [GO:0032072]; regulation of signaling receptor activity [GO:0010469]; regulation of T cell mediated immune response to tumor cell [GO:0002840]; regulation of tolerance induction [GO:0002643]; regulation of transcription by RNA polymerase II [GO:0006357]; T-helper 1 cell activation [GO:0035711]; T-helper 1 cell differentiation [GO:0045063]; toll-like receptor signaling pathway [GO:0002224]; tumor necrosis factor secretion [GO:1990774]; V(D)J recombination [GO:0033151]	angiogenesis [GO:0001525]; cardiac cell fate determination [GO:0060913]; cardiogenic plate morphogenesis [GO:0003142]; cell differentiation [GO:0030154]; cell migration involved in gastrulation [GO:0042074]; cellular response to leukemia inhibitory factor [GO:1990830]; common bile duct development [GO:0061009]; embryonic foregut morphogenesis [GO:0048617]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; endocardial cell differentiation [GO:0060956]; endocardium formation [GO:0060214]; endodermal cell fate determination [GO:0007493]; endodermal digestive tract morphogenesis [GO:0061031]; endoderm formation [GO:0001706]; gall bladder development [GO:0061010]; heart formation [GO:0060914]; heart looping [GO:0001947]; inner cell mass cellular morphogenesis [GO:0001828]; metanephros development [GO:0001656]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; outflow tract morphogenesis [GO:0003151]; positive regulation of cell differentiation [GO:0045597]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; regulation of cardiac cell fate specification [GO:2000043]; regulation of embryonic development [GO:0045995]; regulation of stem cell division [GO:2000035]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification [GO:0060807]; rostrocaudal neural tube patterning [GO:0021903]; signal transduction involved in regulation of gene expression [GO:0023019]; spermatogenesis [GO:0007283]; stem cell fate specification [GO:0048866]; ureter development [GO:0072189]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; cell [GO:0005623]; cell surface [GO:0009986]; condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome [GO:0005768]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; transcriptional repressor complex [GO:0017053]	nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	bubble DNA binding [GO:0000405]; chemoattractant activity [GO:0042056]; C-X-C chemokine binding [GO:0019958]; cytokine activity [GO:0005125]; damaged DNA binding [GO:0003684]; DNA binding, bending [GO:0008301]; DNA polymerase binding [GO:0070182]; double-stranded DNA binding [GO:0003690]; four-way junction DNA binding [GO:0000400]; integrin binding [GO:0005178]; lipopolysaccharide binding [GO:0001530]; lyase activity [GO:0016829]; phosphatidylserine binding [GO:0001786]; RAGE receptor binding [GO:0050786]; repressing transcription factor binding [GO:0070491]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; supercoiled DNA binding [GO:0097100]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	beta-catenin binding [GO:0008013]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2rukb__d5njja___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]; chromatin binding [GO:0003682]; 7-methylguanosine mRNA capping [GO:0006370]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase I promoter [GO:0006361]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription-coupled nucleotide-excision repair [GO:0006283]	apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; extrinsic component of plasma membrane [GO:0019897]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; adherens junction organization [GO:0034332]; axonogenesis [GO:0007409]; lateral ventricle development [GO:0021670]; negative regulation of protein localization to plasma membrane [GO:1903077]; neuroblast division in subventricular zone [GO:0021849]; positive regulation of cell migration [GO:0030335]; positive regulation of neurogenesis [GO:0050769]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]	7-methylguanosine mRNA capping [GO:0006370]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; termination of RNA polymerase I transcription [GO:0006363]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]	adherens junction organization [GO:0034332]; axonogenesis [GO:0007409]; lateral ventricle development [GO:0021670]; negative regulation of protein localization to plasma membrane [GO:1903077]; neuroblast division in subventricular zone [GO:0021849]; positive regulation of cell migration [GO:0030335]; positive regulation of neurogenesis [GO:0050769]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]	nucleoplasm [GO:0005654]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]	apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; extrinsic component of plasma membrane [GO:0019897]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	chromatin binding [GO:0003682]	alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]
d2ruqa1_d2lpva___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]		beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2rvja1_d2lcwa___1	Metazoa	Metazoa	Chordata	Chordata	nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA processing [GO:0006397]; regulation of inner ear auditory receptor cell fate specification [GO:0042669]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	dendritic spine head [GO:0044327]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; estrogen receptor binding [GO:0030331]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; myosin V binding [GO:0031489]; retinoid X receptor binding [GO:0046965]; RNA binding [GO:0003723]; thyroid hormone receptor binding [GO:0046966]; transcription coactivator activity [GO:0003713]; cellular response to calcium ion [GO:0071277]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein homooligomerization [GO:0051260]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]	fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA processing [GO:0006397]; regulation of inner ear auditory receptor cell fate specification [GO:0042669]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	cellular response to calcium ion [GO:0071277]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein homooligomerization [GO:0051260]; regulation of RNA splicing [GO:0043484]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA splicing [GO:0008380]	nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	dendritic spine head [GO:0044327]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]	mRNA binding [GO:0003729]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; estrogen receptor binding [GO:0030331]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; myosin V binding [GO:0031489]; retinoid X receptor binding [GO:0046965]; RNA binding [GO:0003723]; thyroid hormone receptor binding [GO:0046966]; transcription coactivator activity [GO:0003713]
d2sarb__d1lowa___1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			extracellular region [GO:0005576]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d2sasa__d2luxb___1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]		intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]		extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	calcium ion binding [GO:0005509]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]
d2scpa__d2isda1__1	Metazoa	Metazoa	Annelida	Chordata	calcium ion binding [GO:0005509]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]		G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]
d2sebb2_d4huwc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2sfaa__d6b6ra___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2sgee__d1ct0e___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	serine-type endopeptidase inhibitor activity [GO:0004867]	serine-type endopeptidase inhibitor activity [GO:0004867]
d2sgfe__d1p05a___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d2sgqe__d3pyha___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2shpb2_d2ciaa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]; abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; postsynaptic density [GO:0014069]; vesicle membrane [GO:0012506]; cytoskeletal adaptor activity [GO:0008093]; phosphotyrosine residue binding [GO:0001784]; protein-containing complex binding [GO:0044877]; receptor signaling complex adaptor activity [GO:0030159]; scaffold protein binding [GO:0097110]; SH3/SH2 adaptor activity [GO:0005070]; actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; postsynaptic density [GO:0014069]; vesicle membrane [GO:0012506]	cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]	cytoskeletal adaptor activity [GO:0008093]; phosphotyrosine residue binding [GO:0001784]; protein-containing complex binding [GO:0044877]; receptor signaling complex adaptor activity [GO:0030159]; scaffold protein binding [GO:0097110]; SH3/SH2 adaptor activity [GO:0005070]
d2slia2_d3gvkb1__1	Metazoa		Annelida		extracellular space [GO:0005615]; anhydrosialidase activity [GO:0033995]; exo-alpha-sialidase activity [GO:0004308]; carbohydrate metabolic process [GO:0005975]	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	virus tail, fiber [GO:0098024]	anhydrosialidase activity [GO:0033995]; exo-alpha-sialidase activity [GO:0004308]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]
d2slia2_d4cpze___1	Metazoa		Annelida	Negarnaviricota	extracellular space [GO:0005615]; anhydrosialidase activity [GO:0033995]; exo-alpha-sialidase activity [GO:0004308]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	anhydrosialidase activity [GO:0033995]; exo-alpha-sialidase activity [GO:0004308]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d2snwa__d3urea___1				Proteobacteria	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]		host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]	serine-type endopeptidase activity [GO:0004252]
d2spla__d4gxea___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2spna__d2vjrb___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2spoa__d5nb4d___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2sqcb2_d1tnyb___1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d2st1a__d1af4a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2stae__d3sj9a___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	digestion [GO:0007586]	transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	extracellular space [GO:0005615]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]
d2tbsa__d1bmaa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2tbva__d1a6ca2__1					T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]			T=3 icosahedral viral capsid [GO:0039617]	viral capsid [GO:0019028]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d2tbvb__d5cfca___1					T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2tdma__d4iqqc___1		Metazoa	Firmicutes	Nematoda (roundworms)	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]	cytoplasm [GO:0005737]		thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d2tece__d1zvka___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2tepb__d2ifwb___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	aspartic-type endopeptidase activity [GO:0004190]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	aspartic-type endopeptidase activity [GO:0004190]
d2tgaa__d4dgja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	brush border [GO:0005903]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; scavenger receptor activity [GO:0005044]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	brush border [GO:0005903]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	scavenger receptor activity [GO:0005044]; serine-type endopeptidase activity [GO:0004252]
d2tgpz__d2vvca___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d2thf.1_d1qcpa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2thia__d1a8fa___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; thiamine pyridinylase activity [GO:0050332]; thiamine catabolic process [GO:0009230]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	thiamine catabolic process [GO:0009230]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	thiamine pyridinylase activity [GO:0050332]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d2thib__d5i84b___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; thiamine pyridinylase activity [GO:0050332]; thiamine catabolic process [GO:0009230]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; phosphate ion binding [GO:0042301]; phosphate ion transmembrane transport [GO:0035435]	thiamine catabolic process [GO:0009230]	phosphate ion transmembrane transport [GO:0035435]	extracellular region [GO:0005576]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	thiamine pyridinylase activity [GO:0050332]	phosphate ion binding [GO:0042301]
d2tira__d3m9ja___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d2tira__d4yqvc1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d2tldi__d4hx2d___1	Metazoa		Chordata	Actinobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	serine-type endopeptidase inhibitor activity [GO:0004867]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase inhibitor activity [GO:0004867]
d2tlxa__d3dpea___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]		collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d2tlxa__d3msna___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d2tmdb1_d3atzc___1			Proteobacteria		4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]					4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d2tmgb2_d2yfhf1__1			Thermotogae	Proteobacteria	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	cellular amino acid metabolic process [GO:0006520]	glutamate biosynthetic process [GO:0006537]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]
d2tmgc2_d3k92c1__1			Thermotogae	Firmicutes	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]			glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	glutamate dehydrogenase (NAD+) activity [GO:0004352]
d2tmgd2_d3tnlc1__1			Thermotogae	Firmicutes	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d2tmge2_d5ijzi1__1			Thermotogae	Actinobacteria	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; glutamate biosynthetic process [GO:0006537]	cellular amino acid metabolic process [GO:0006520]	glutamate biosynthetic process [GO:0006537]		cytoplasm [GO:0005737]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	glutamate dehydrogenase (NADP+) activity [GO:0004354]
d2tmgf2_d4fccl1__1			Thermotogae	Proteobacteria	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]			glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d2tn4a__d1ncza___1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]; troponin T binding [GO:0031014]	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]		regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]		troponin complex [GO:0005861]	calcium ion binding [GO:0005509]; troponin T binding [GO:0031014]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]
d2tn4a__d2l5xb___1	Metazoa	Metazoa	Chordata	Chordata	calcium ion binding [GO:0005509]; troponin T binding [GO:0031014]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]		cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; troponin T binding [GO:0031014]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d2tprb2_d2yvja2__1				Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]; cell redox homeostasis [GO:0045454]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; aromatic compound catabolic process [GO:0019439]	cell redox homeostasis [GO:0045454]	aromatic compound catabolic process [GO:0019439]	cell [GO:0005623]; cytoplasm [GO:0005737]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2tprb2_d3cpih1__1		Fungi		Ascomycota	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]; cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	cell redox homeostasis [GO:0045454]	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]	GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]
d2tpta1_d1zyka1__1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; membrane [GO:0016020]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]	tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]
d2trcb__d2ovrb2__1	Metazoa	Metazoa	Chordata	Chordata	heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; photoreceptor disc membrane [GO:0097381]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; SCF ubiquitin ligase complex [GO:0019005]; cyclin binding [GO:0030332]; identical protein binding [GO:0042802]; phosphothreonine residue binding [GO:0050816]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lipid homeostasis [GO:0055088]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; post-translational protein modification [GO:0043687]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; regulation of lipid storage [GO:0010883]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lipid homeostasis [GO:0055088]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; post-translational protein modification [GO:0043687]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; regulation of lipid storage [GO:0010883]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; ubiquitin recycling [GO:0010992]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; photoreceptor disc membrane [GO:0097381]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; SCF ubiquitin ligase complex [GO:0019005]		cyclin binding [GO:0030332]; identical protein binding [GO:0042802]; phosphothreonine residue binding [GO:0050816]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activator activity [GO:0097027]
d2trha__d5cnhb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d2trsb__d1pwhb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	cytoplasm [GO:0005737]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]; gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]	tryptophan biosynthetic process [GO:0000162]	gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]
d2trta1_d4xk4a1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	protein-DNA complex [GO:0032993]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]		protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2tsaa__d2ih8b1__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	oxidation-reduction process [GO:0055114]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2tsaa__d4p5sa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2tsab__d3rymd___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2tsad__d2fqda2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d2tsba__d3fpya___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2tsbb__d3omnb2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2tsbc__d2xwzf2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2tsbd__d2fnwa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2tssa2_d1d5mc2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	extracellular region [GO:0005576]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	toxin activity [GO:0090729]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d2tssb1_d2bosc___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d2tssc1_d1bcpl___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d2tund__d1osgc___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]
d2tysb__d2bhtc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	cytoplasm [GO:0005737]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	tryptophan biosynthetic process [GO:0000162]	cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]
d2u2fa__d4ckoh4__1	Metazoa		Chordata		commitment complex [GO:0000243]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type prespliceosome [GO:0071004]; U2AF [GO:0089701]; C2H2 zinc finger domain binding [GO:0070742]; enzyme binding [GO:0019899]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA 3'-splice site binding [GO:0030628]; RNA binding [GO:0003723]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of RNA splicing [GO:0033120]; RNA export from nucleus [GO:0006405]		mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of RNA splicing [GO:0033120]; RNA export from nucleus [GO:0006405]		commitment complex [GO:0000243]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2AF [GO:0089701]; U2-type prespliceosome [GO:0071004]		C2H2 zinc finger domain binding [GO:0070742]; enzyme binding [GO:0019899]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA 3'-splice site binding [GO:0030628]; RNA binding [GO:0003723]	
d2ulla__d3w94a___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	membrane [GO:0016020]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]	membrane [GO:0016020]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d2up1a1_d2disa1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; cytidine to uridine editing [GO:0016554]; hematopoietic progenitor cell differentiation [GO:0002244]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cytidine to uridine editing [GO:0016554]; hematopoietic progenitor cell differentiation [GO:0002244]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	nucleus [GO:0005634]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d2uu8a__d1uypb1__1	Viridiplantae		Streptophyta	Thermotogae	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			mannose binding [GO:0005537]; metal ion binding [GO:0046872]	beta-fructofuranosidase activity [GO:0004564]
d2uu9e2_d2z4me2__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d2uu9l1_d2qoyl1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d2uuae1_d1h74c1__1			Deinococcus-Thermus	Euryarchaeota	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]	translation [GO:0006412]	threonine biosynthetic process [GO:0009088]	ribosome [GO:0005840]	cytoplasm [GO:0005737]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]
d2uuae1_d3jb9b5__1		Fungi	Deinococcus-Thermus	Ascomycota	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; post-mRNA release spliceosomal complex [GO:0071014]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387]	translation [GO:0006412]	mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387]	ribosome [GO:0005840]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; post-mRNA release spliceosomal complex [GO:0071014]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d2uuae2_d2i2pe2__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d2uubh1_d1vs7h1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d2uubj1_d2qbbj1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d2uuce1_d2f1dm2__1		Viridiplantae	Deinococcus-Thermus	Streptophyta	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	translation [GO:0006412]	histidine biosynthetic process [GO:0000105]	ribosome [GO:0005840]	chloroplast [GO:0009507]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2uucq1_d1ewia___1		Metazoa	Deinococcus-Thermus	Chordata	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]; damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	translation [GO:0006412]	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	ribosome [GO:0005840]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]
d2uudk__d3bd5a___1												
d2uudl__d3b2ud1__1		Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2uued1_d5if1d2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2uugb__d1muga___1			Proteobacteria	Proteobacteria	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; pyrimidine-specific mismatch base pair DNA N-glycosylase activity [GO:0008263]; base-excision repair, AP site formation [GO:0006285]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair, AP site formation [GO:0006285]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	uracil DNA N-glycosylase activity [GO:0004844]	DNA binding [GO:0003677]; pyrimidine-specific mismatch base pair DNA N-glycosylase activity [GO:0008263]
d2uulc__d2vmlh___1				Cyanobacteria		phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]		
d2uulc__d3w4uf___1		Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uuld__d2uunq___1												
d2uulg__d5kkka___1		Metazoa		Chordata		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uull__d1o1lb___1		Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uull__d2vmle___1				Cyanobacteria		phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]		
d2uulr__d5aqdl___1				Cyanobacteria		phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]		
d2uulv__d2uump___1				Cyanobacteria		phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]		
d2uumc__d5x2sb___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uumd__d1mnob___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uumd__d5nb3d___1			Cyanobacteria	Cyanobacteria	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	phycobilisome [GO:0030089]	phycobilisome [GO:0030089]		
d2uume__d5ufjb___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uumf__d2aa1b1__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uumh__d1ha7k___1			Cyanobacteria	Cyanobacteria	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	phycobilisome [GO:0030089]	phycobilisome [GO:0030089]		
d2uums__d2uuna___1			Cyanobacteria		phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]			
d2uumt__d3eu1b___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uumx__d1m6ma___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uunb__d3d17a___1		Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uunc__d4tyxa___1		Metazoa		Chordata		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uung__d2c7lb___1				Cyanobacteria		phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]		
d2uunn__d3a5ba___1		Metazoa		Arthropoda		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uuno__d1nz3a___1		Metazoa		Chordata		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uuno__d2bv8k___1				Rhodophyta		chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]		
d2uunr__d5fvbl___1				Cyanobacteria		phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]		
d2uuns__d1ns9b___1		Metazoa		Chordata		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uunv__d1v4wd___1		Metazoa		Chordata		hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2uunx__d2vmla___1				Cyanobacteria		phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]		
d2uupa2_d1gqqa2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]	ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]
d2uupa2_d4hv4b3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]	ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]
d2uusa__d3o3qd___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2uuya__d1vcpc___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2uv3a1_d2cdfa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2uv3b1_d1c5cl2__1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]		cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]		cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]	
d2uv3b1_d5jymd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d2uvdc__d2x86i___1			Firmicutes	Proteobacteria	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; fatty acid biosynthetic process [GO:0006633]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	fatty acid biosynthetic process [GO:0006633]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]			3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]
d2uvdd__d1psdb1__1			Firmicutes	Proteobacteria	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	fatty acid biosynthetic process [GO:0006633]	L-serine biosynthetic process [GO:0006564]		cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]
d2uvde__d2hk9c2__1			Firmicutes	Aquificae	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	fatty acid biosynthetic process [GO:0006633]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d2uvde__d2zeac___1			Firmicutes		3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]				3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]	
d2uvdf__d3bhia___1		Metazoa	Firmicutes	Chordata	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; 15-hydroxyprostaglandin dehydrogenase (NADP+) activity [GO:0047021]; carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; prostaglandin-E2 9-reductase activity [GO:0050221]; cyclooxygenase pathway [GO:0019371]; drug metabolic process [GO:0017144]; epithelial cell differentiation [GO:0030855]; oxidation-reduction process [GO:0055114]; vitamin K metabolic process [GO:0042373]	fatty acid biosynthetic process [GO:0006633]	cyclooxygenase pathway [GO:0019371]; drug metabolic process [GO:0017144]; epithelial cell differentiation [GO:0030855]; oxidation-reduction process [GO:0055114]; vitamin K metabolic process [GO:0042373]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]	15-hydroxyprostaglandin dehydrogenase (NADP+) activity [GO:0047021]; carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; prostaglandin-E2 9-reductase activity [GO:0050221]
d2uvdg__d4n5nb___1			Firmicutes	Proteobacteria	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetoacetyl-CoA reductase activity [GO:0018454]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]	acetoacetyl-CoA reductase activity [GO:0018454]
d2uvdh__d3rkub1__1		Fungi	Firmicutes	Ascomycota	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity [GO:0016491]; serine 3-dehydrogenase activity [GO:0031132]	fatty acid biosynthetic process [GO:0006633]			cytoplasm [GO:0005737]; nucleus [GO:0005634]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]	carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity [GO:0016491]; serine 3-dehydrogenase activity [GO:0031132]
d2uvha__d3delb1__1				Chlamydiae		cell surface [GO:0009986]; extracellular region [GO:0005576]; amino acid transport [GO:0006865]		amino acid transport [GO:0006865]		cell surface [GO:0009986]; extracellular region [GO:0005576]		
d2uvha__d4u2rd___1		Metazoa		Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2uvja__d4lonb___1				Proteobacteria		cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; cysteine biosynthetic process [GO:0019344]		cysteine biosynthetic process [GO:0019344]		cytoplasm [GO:0005737]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2uvva1_d2c2ra1__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d2uw1a__d1fz5d___1				Proteobacteria		metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]		cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]				metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2uw1b__d1pj0b___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2uw1b__d5v5ka___1				Euryarchaeota		cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]
d2uwea2_d1agea2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2uweb2_d1t04d2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2uwee1_d4tyua___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2uwee2_d1y18a2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2uwef2_d1iray1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]
d2uweh1_d1y0la1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2uweh1_d2agjl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2uwei2_d1igyb3__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2uwei2_d5wkid1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2uwem1_d1kiqb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2uwem1_d3gsrb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2uwfa1_d1kxta2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	xylan catabolic process [GO:0045493]	carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	endo-1,4-beta-xylanase activity [GO:0031176]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d2uwhf__d3kx5b___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d2uwhf__d3ofuc___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]			cytoplasm [GO:0005737]		aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2uwpa__d3sjia___1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]
d2ux0a1_d3mg2b2__1	Metazoa		Chordata	Cyanobacteria	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; interferon-gamma-mediated signaling pathway [GO:0060333]; nervous system development [GO:0007399]; regulation of calcium ion transport [GO:0051924]; regulation of cellular response to heat [GO:1900034]; regulation of skeletal muscle adaptation [GO:0014733]	phycobilisome [GO:0030089]; chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]; light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; interferon-gamma-mediated signaling pathway [GO:0060333]; nervous system development [GO:0007399]; regulation of calcium ion transport [GO:0051924]; regulation of cellular response to heat [GO:1900034]; regulation of skeletal muscle adaptation [GO:0014733]	light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum membrane [GO:0033017]	phycobilisome [GO:0030089]	ATP binding [GO:0005524]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]
d2ux0b__d3t8ua___1	Metazoa		Chordata	Proteobacteria	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; interferon-gamma-mediated signaling pathway [GO:0060333]; nervous system development [GO:0007399]; regulation of calcium ion transport [GO:0051924]; regulation of cellular response to heat [GO:1900034]; regulation of skeletal muscle adaptation [GO:0014733]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; interferon-gamma-mediated signaling pathway [GO:0060333]; nervous system development [GO:0007399]; regulation of calcium ion transport [GO:0051924]; regulation of cellular response to heat [GO:1900034]; regulation of skeletal muscle adaptation [GO:0014733]	steroid metabolic process [GO:0008202]	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum membrane [GO:0033017]		ATP binding [GO:0005524]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	steroid delta-isomerase activity [GO:0004769]
d2ux0d__d3nv0b___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; interferon-gamma-mediated signaling pathway [GO:0060333]; nervous system development [GO:0007399]; regulation of calcium ion transport [GO:0051924]; regulation of cellular response to heat [GO:1900034]; regulation of skeletal muscle adaptation [GO:0014733]	nucleus [GO:0005634]; RNA binding [GO:0003723]; poly(A)+ mRNA export from nucleus [GO:0016973]	cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; interferon-gamma-mediated signaling pathway [GO:0060333]; nervous system development [GO:0007399]; regulation of calcium ion transport [GO:0051924]; regulation of cellular response to heat [GO:1900034]; regulation of skeletal muscle adaptation [GO:0014733]	poly(A)+ mRNA export from nucleus [GO:0016973]	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum membrane [GO:0033017]	nucleus [GO:0005634]	ATP binding [GO:0005524]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	RNA binding [GO:0003723]
d2ux0e__d5tuwd2__1	Metazoa		Chordata	Cyanobacteria	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; interferon-gamma-mediated signaling pathway [GO:0060333]; nervous system development [GO:0007399]; regulation of calcium ion transport [GO:0051924]; regulation of cellular response to heat [GO:1900034]; regulation of skeletal muscle adaptation [GO:0014733]	phycobilisome [GO:0030089]; chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]; light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	cell differentiation [GO:0030154]; insulin secretion [GO:0030073]; interferon-gamma-mediated signaling pathway [GO:0060333]; nervous system development [GO:0007399]; regulation of calcium ion transport [GO:0051924]; regulation of cellular response to heat [GO:1900034]; regulation of skeletal muscle adaptation [GO:0014733]	light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; sarcoplasmic reticulum membrane [GO:0033017]	phycobilisome [GO:0030089]	ATP binding [GO:0005524]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]
d2ux1a__d4xkub___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2ux1a__d5v5kg___1			Firmicutes	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]
d2ux1g__d1veqg___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2ux1i__d2fkzd___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2ux7a__d3ppsd3__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]			periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2ux9a1_d2v18i___1			Deinococcus-Thermus	Deinococcus-Thermus	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2ux9b__d2ciea___1			Deinococcus-Thermus	Euryarchaeota	nucleotide binding [GO:0000166]	cytosol [GO:0005829]				cytosol [GO:0005829]	nucleotide binding [GO:0000166]	
d2ux9c__d3oqta___1			Deinococcus-Thermus	Actinobacteria	nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2uxaa__d1a54a___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	phosphate ion binding [GO:0042301]
d2uxac__d2qs4c___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d2uxbq1_d1qzhb___1		Fungi	Deinococcus-Thermus	Ascomycota	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytosol [GO:0005829]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]; nuclear telomeric heterochromatin [GO:0005724]; nucleus [GO:0005634]; shelterin complex [GO:0070187]; telomere cap complex [GO:0000782]; G-rich strand telomeric DNA binding [GO:0098505]; single-stranded telomeric DNA binding [GO:0043047]; telomerase inhibitor activity [GO:0010521]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]	translation [GO:0006412]	negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]	ribosome [GO:0005840]	cytosol [GO:0005829]; nuclear chromosome, telomeric region [GO:0000784]; nuclear telomere cap complex [GO:0000783]; nuclear telomeric heterochromatin [GO:0005724]; nucleus [GO:0005634]; shelterin complex [GO:0070187]; telomere cap complex [GO:0000782]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	G-rich strand telomeric DNA binding [GO:0098505]; single-stranded telomeric DNA binding [GO:0043047]; telomerase inhibitor activity [GO:0010521]
d2uxci1_d2f1dp1__1		Viridiplantae	Deinococcus-Thermus	Streptophyta	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	translation [GO:0006412]	histidine biosynthetic process [GO:0000105]	ribosome [GO:0005840]	chloroplast [GO:0009507]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2uxcq1_d1xpre2__1			Deinococcus-Thermus	Proteobacteria	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	translation [GO:0006412]	DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	ribosome [GO:0005840]	cytosol [GO:0005829]; membrane [GO:0016020]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]
d2uxdi1_d2f1dl1__1		Viridiplantae	Deinococcus-Thermus	Streptophyta	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]	translation [GO:0006412]	histidine biosynthetic process [GO:0000105]	ribosome [GO:0005840]	chloroplast [GO:0009507]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d2uxdq1_d1c0aa1__1			Deinococcus-Thermus	Proteobacteria	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	translation [GO:0006412]	aspartyl-tRNA aminoacylation [GO:0006422]	ribosome [GO:0005840]	cytosol [GO:0005829]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]
d2uxfa__d5d4hb2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2uxga__d1niac2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2uxsb1_d3ej0a___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d2uxxa1_d2aqea1__1	Metazoa	Metazoa	Chordata	Chordata	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; chromosome [GO:0005694]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; SAGA-type complex [GO:0070461]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; mitotic cell cycle [GO:0000278]; positive regulation of histone acetylation [GO:0035066]; regulation of histone deacetylation [GO:0031063]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; mitotic cell cycle [GO:0000278]; positive regulation of histone acetylation [GO:0035066]; regulation of histone deacetylation [GO:0031063]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; chromosome [GO:0005694]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; SAGA-type complex [GO:0070461]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]
d2uy0b__d1uh8a___1		Fungi		Mucoromycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2uy6c__d1n67a1__1			Proteobacteria	Firmicutes	outer membrane-bounded periplasmic space [GO:0030288]; cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	outer membrane-bounded periplasmic space [GO:0030288]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]		
d2uy7a1_d2msph___1		Metazoa	Proteobacteria	Nematoda (roundworms)	outer membrane-bounded periplasmic space [GO:0030288]; cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]; identical protein binding [GO:0042802]	cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]		outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]		identical protein binding [GO:0042802]
d2uy7e1_d2mspb___1		Metazoa	Proteobacteria	Nematoda (roundworms)	outer membrane-bounded periplasmic space [GO:0030288]; cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]; identical protein binding [GO:0042802]	cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]		outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]		identical protein binding [GO:0042802]
d2uy8a__d4xfba___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]; oxalate decarboxylase activity [GO:0046564]; oxalate metabolic process [GO:0033609]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	oxalate metabolic process [GO:0033609]	cysteine metabolic process [GO:0006534]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]; oxalate decarboxylase activity [GO:0046564]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d2uy9a__d4xeza___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]; oxalate decarboxylase activity [GO:0046564]; oxalate metabolic process [GO:0033609]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	oxalate metabolic process [GO:0033609]	cysteine metabolic process [GO:0006534]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]; oxalate decarboxylase activity [GO:0046564]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d2uyaa__d2eteb___1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]; oxalate decarboxylase activity [GO:0046564]; oxalate metabolic process [GO:0033609]	apoplast [GO:0048046]; cell wall [GO:0005618]; superoxide dismutase complex [GO:1902693]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; nutrient reservoir activity [GO:0045735]; oxalate oxidase activity [GO:0050162]; superoxide dismutase activity [GO:0004784]; cell wall organization [GO:0071555]; oxidation-reduction process [GO:0055114]; protein homooligomerization [GO:0051260]; removal of superoxide radicals [GO:0019430]	oxalate metabolic process [GO:0033609]	cell wall organization [GO:0071555]; oxidation-reduction process [GO:0055114]; protein homooligomerization [GO:0051260]; removal of superoxide radicals [GO:0019430]	cytoplasm [GO:0005737]	apoplast [GO:0048046]; cell wall [GO:0005618]; superoxide dismutase complex [GO:1902693]	metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]; oxalate decarboxylase activity [GO:0046564]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; nutrient reservoir activity [GO:0045735]; oxalate oxidase activity [GO:0050162]; superoxide dismutase activity [GO:0004784]
d2uyea1_d3h7ma___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]				integral component of membrane [GO:0016021]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]
d2uyfa1_d1iz1p2__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]					DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2uyla1_d1mccb2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2uylm1_d12e8m2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2uylv2_d1jnhd2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	plasma membrane [GO:0005886]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2uylv2_d5ezll1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2uylx1_d1iaih1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2uylx2_d3cfii1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; type II protein secretion system complex [GO:0015627]; protein secretion by the type II secretion system [GO:0015628]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	protein secretion by the type II secretion system [GO:0015628]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; type II protein secretion system complex [GO:0015627]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2uyvd__d1gt7a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]
d2uyyb2_d3pdua2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]		cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]		chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491]	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]
d2uyzb__d3b08d1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2uz4a__d1jqea___1		Metazoa	Proteobacteria	Chordata	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; histamine N-methyltransferase activity [GO:0046539]; brain development [GO:0007420]; histamine catabolic process [GO:0001695]; histidine catabolic process [GO:0006548]; hyperosmotic response [GO:0006972]; methylation [GO:0032259]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to amine [GO:0014075]; response to cocaine [GO:0042220]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to interleukin-1 [GO:0070555]; response to tumor cell [GO:0002347]	DNA restriction-modification system [GO:0009307]	brain development [GO:0007420]; histamine catabolic process [GO:0001695]; histidine catabolic process [GO:0006548]; hyperosmotic response [GO:0006972]; methylation [GO:0032259]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to amine [GO:0014075]; response to cocaine [GO:0042220]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to interleukin-1 [GO:0070555]; response to tumor cell [GO:0002347]		centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	histamine N-methyltransferase activity [GO:0046539]
d2uz4a__d2z6aa___1			Proteobacteria	Proteobacteria	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d2uz5a__d1fkda___1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; pathogenesis [GO:0009405]; protein folding [GO:0006457]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	pathogenesis [GO:0009405]; protein folding [GO:0006457]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell outer membrane [GO:0009279]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]
d2uzaa3_d3exff2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2uzca__d2awwa___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell projection [GO:0042995]; cell-cell adherens junction [GO:0005913]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; membrane [GO:0016020]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; actinin binding [GO:0042805]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase C binding [GO:0005080]; protein N-terminus binding [GO:0047485]; actin cytoskeleton organization [GO:0030036]; cell growth involved in cardiac muscle cell development [GO:0061049]; heart development [GO:0007507]; muscle structure development [GO:0061061]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of synapse assembly [GO:0051963]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	actin cytoskeleton organization [GO:0030036]; cell growth involved in cardiac muscle cell development [GO:0061049]; heart development [GO:0007507]; muscle structure development [GO:0061061]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of synapse assembly [GO:0051963]	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; positive regulation of potassium ion transport [GO:0043268]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of protein localization [GO:0032880]	actin cytoskeleton [GO:0015629]; cell-cell adherens junction [GO:0005913]; cell projection [GO:0042995]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; membrane [GO:0016020]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; stress fiber [GO:0001725]; Z disc [GO:0030018]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; microvillus [GO:0005902]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; paranode region of axon [GO:0033270]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; T-tubule [GO:0030315]	actin binding [GO:0003779]; actinin binding [GO:0042805]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; protein kinase C binding [GO:0005080]; protein N-terminus binding [GO:0047485]	ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]
d2uzdb1_d1qmzd2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2uzeb1_d2cchb2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2uzed1_d4bchb1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2uzlb2_d1ad6a___1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]; androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d2uzpb__d1cjyb1__1	Metazoa	Metazoa	Chordata	Chordata	calyx of Held [GO:0044305]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; presynaptic cytosol [GO:0099523]; synaptic membrane [GO:0097060]; ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; zinc ion binding [GO:0008270]; chemical synaptic transmission [GO:0007268]; chemosensory behavior [GO:0007635]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; platelet activation [GO:0030168]; positive regulation of mismatch repair [GO:0032425]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of phagocytosis [GO:0050764]; regulation of response to food [GO:0032095]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to morphine [GO:0043278]; response to pain [GO:0048265]; response to psychosocial stress [GO:1990911]; rhythmic process [GO:0048511]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; calcium-dependent phospholipid binding [GO:0005544]; lysophospholipase activity [GO:0004622]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; cardiolipin acyl-chain remodeling [GO:0035965]; cellular response to antibiotic [GO:0071236]; glycerophospholipid catabolic process [GO:0046475]; icosanoid biosynthetic process [GO:0046456]; icosanoid metabolic process [GO:0006690]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; platelet activating factor biosynthetic process [GO:0006663]; regulation of cell population proliferation [GO:0042127]	chemical synaptic transmission [GO:0007268]; chemosensory behavior [GO:0007635]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; platelet activation [GO:0030168]; positive regulation of mismatch repair [GO:0032425]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of phagocytosis [GO:0050764]; regulation of response to food [GO:0032095]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to morphine [GO:0043278]; response to pain [GO:0048265]; response to psychosocial stress [GO:1990911]; rhythmic process [GO:0048511]	arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; cardiolipin acyl-chain remodeling [GO:0035965]; cellular response to antibiotic [GO:0071236]; glycerophospholipid catabolic process [GO:0046475]; icosanoid biosynthetic process [GO:0046456]; icosanoid metabolic process [GO:0006690]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; platelet activating factor biosynthetic process [GO:0006663]; regulation of cell population proliferation [GO:0042127]	calyx of Held [GO:0044305]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; presynaptic cytosol [GO:0099523]; synaptic membrane [GO:0097060]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; lipid droplet [GO:0005811]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]	ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; lysophospholipase activity [GO:0004622]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]
d2uzpc__d5lo8a___1	Metazoa	Metazoa	Chordata	Chordata	calyx of Held [GO:0044305]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; presynaptic cytosol [GO:0099523]; synaptic membrane [GO:0097060]; ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; zinc ion binding [GO:0008270]; chemical synaptic transmission [GO:0007268]; chemosensory behavior [GO:0007635]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; platelet activation [GO:0030168]; positive regulation of mismatch repair [GO:0032425]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of phagocytosis [GO:0050764]; regulation of response to food [GO:0032095]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to morphine [GO:0043278]; response to pain [GO:0048265]; response to psychosocial stress [GO:1990911]; rhythmic process [GO:0048511]	cell junction [GO:0030054]; cholinergic synapse [GO:0098981]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extrinsic component of membrane [GO:0019898]; extrinsic component of synaptic vesicle membrane [GO:0098850]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphate ion binding [GO:0042301]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; selenium binding [GO:0008430]; zinc ion binding [GO:0008270]; brain development [GO:0007420]; dendritic spine organization [GO:0097061]; intracellular protein transport [GO:0006886]; regulation of NMDA receptor activity [GO:2000310]	chemical synaptic transmission [GO:0007268]; chemosensory behavior [GO:0007635]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; platelet activation [GO:0030168]; positive regulation of mismatch repair [GO:0032425]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of phagocytosis [GO:0050764]; regulation of response to food [GO:0032095]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to morphine [GO:0043278]; response to pain [GO:0048265]; response to psychosocial stress [GO:1990911]; rhythmic process [GO:0048511]	brain development [GO:0007420]; dendritic spine organization [GO:0097061]; intracellular protein transport [GO:0006886]; regulation of NMDA receptor activity [GO:2000310]	calyx of Held [GO:0044305]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; presynaptic cytosol [GO:0099523]; synaptic membrane [GO:0097060]	cell junction [GO:0030054]; cholinergic synapse [GO:0098981]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extrinsic component of membrane [GO:0019898]; extrinsic component of synaptic vesicle membrane [GO:0098850]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]	ATP binding [GO:0005524]; calcium-dependent protein kinase C activity [GO:0004698]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; zinc ion binding [GO:0008270]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphate ion binding [GO:0042301]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; selenium binding [GO:0008430]; zinc ion binding [GO:0008270]
d2uzqc2_d1c25a___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]; phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chaperone binding [GO:0051087]; phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; cellular response to UV [GO:0034644]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of mitotic cell cycle [GO:0045931]; protein deubiquitination [GO:0016579]; regulation of cell cycle [GO:0051726]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to radiation [GO:0009314]	cell division [GO:0051301]; female meiosis I [GO:0007144]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; oocyte maturation [GO:0001556]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	cell division [GO:0051301]; cell population proliferation [GO:0008283]; cellular response to UV [GO:0034644]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of G2/MI transition of meiotic cell cycle [GO:0110032]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitotic cell cycle [GO:0045931]; protein deubiquitination [GO:0016579]; regulation of cell cycle [GO:0051726]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to radiation [GO:0009314]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle pole [GO:0000922]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]	chaperone binding [GO:0051087]; phosphoprotein phosphatase activity [GO:0004721]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]
d2uzsa__d2cayb1__1	Metazoa	Fungi	Chordata	Ascomycota	cell-cell junction [GO:0005911]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; vesicle [GO:0031982]; 14-3-3 protein binding [GO:0071889]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein phosphatase 2A binding [GO:0051721]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; activation of protein kinase B activity [GO:0032148]; activation-induced cell death of T cells [GO:0006924]; aging [GO:0007568]; anoikis [GO:0043276]; apoptotic mitochondrial changes [GO:0008637]; carbohydrate transport [GO:0008643]; cell differentiation [GO:0030154]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell population proliferation [GO:0008283]; cell projection organization [GO:0030030]; cellular protein modification process [GO:0006464]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidised low-density lipoprotein particle stimulus [GO:0140052]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; endocrine pancreas development [GO:0031018]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization to mitochondrion [GO:0072655]; excitatory postsynaptic potential [GO:0060079]; execution phase of apoptosis [GO:0097194]; G protein-coupled receptor signaling pathway [GO:0007186]; germ cell development [GO:0007281]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen cell differentiation involved in embryonic placenta development [GO:0060709]; hyaluronan metabolic process [GO:0030212]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; interleukin-18-mediated signaling pathway [GO:0035655]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; maintenance of protein location in mitochondrion [GO:0072656]; mammary gland epithelial cell differentiation [GO:0060644]; maternal placenta development [GO:0001893]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of lymphocyte migration [GO:2000402]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase activity by protein phosphorylation [GO:0100002]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of proteolysis [GO:0045861]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; NIK/NF-kappaB signaling [GO:0038061]; nitric oxide biosynthetic process [GO:0006809]; osteoblast differentiation [GO:0001649]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peripheral nervous system myelin maintenance [GO:0032287]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphorylation [GO:0016310]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of organ growth [GO:0046622]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of mRNA stability [GO:0043488]; regulation of myelination [GO:0031641]; regulation of neuron projection development [GO:0010975]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of translation [GO:0006417]; response to fluid shear stress [GO:0034405]; response to food [GO:0032094]; response to growth hormone [GO:0060416]; response to heat [GO:0009408]; response to insulin-like growth factor stimulus [GO:1990418]; response to oxidative stress [GO:0006979]; response to UV-A [GO:0070141]; signal transduction [GO:0007165]; spinal cord development [GO:0021510]; striated muscle cell differentiation [GO:0051146]; T cell costimulation [GO:0031295]; TOR signaling [GO:0031929]; translation [GO:0006412]	cell [GO:0005623]; ESCRT II complex [GO:0000814]; late endosome membrane [GO:0031902]; metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266]; ubiquitin binding [GO:0043130]; ATP export [GO:1904669]; carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [GO:0000433]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	activation-induced cell death of T cells [GO:0006924]; activation of protein kinase B activity [GO:0032148]; aging [GO:0007568]; anoikis [GO:0043276]; apoptotic mitochondrial changes [GO:0008637]; carbohydrate transport [GO:0008643]; cell differentiation [GO:0030154]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell population proliferation [GO:0008283]; cell projection organization [GO:0030030]; cellular protein modification process [GO:0006464]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidised low-density lipoprotein particle stimulus [GO:0140052]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; endocrine pancreas development [GO:0031018]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization to mitochondrion [GO:0072655]; excitatory postsynaptic potential [GO:0060079]; execution phase of apoptosis [GO:0097194]; germ cell development [GO:0007281]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen cell differentiation involved in embryonic placenta development [GO:0060709]; G protein-coupled receptor signaling pathway [GO:0007186]; hyaluronan metabolic process [GO:0030212]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-18-mediated signaling pathway [GO:0035655]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; maintenance of protein location in mitochondrion [GO:0072656]; mammary gland epithelial cell differentiation [GO:0060644]; maternal placenta development [GO:0001893]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of lymphocyte migration [GO:2000402]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase activity by protein phosphorylation [GO:0100002]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of proteolysis [GO:0045861]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; NIK/NF-kappaB signaling [GO:0038061]; nitric oxide biosynthetic process [GO:0006809]; osteoblast differentiation [GO:0001649]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peripheral nervous system myelin maintenance [GO:0032287]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphorylation [GO:0016310]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of organ growth [GO:0046622]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of mRNA stability [GO:0043488]; regulation of myelination [GO:0031641]; regulation of neuron projection development [GO:0010975]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of translation [GO:0006417]; response to fluid shear stress [GO:0034405]; response to food [GO:0032094]; response to growth hormone [GO:0060416]; response to heat [GO:0009408]; response to insulin-like growth factor stimulus [GO:1990418]; response to oxidative stress [GO:0006979]; response to UV-A [GO:0070141]; signal transduction [GO:0007165]; spinal cord development [GO:0021510]; striated muscle cell differentiation [GO:0051146]; T cell costimulation [GO:0031295]; TOR signaling [GO:0031929]; translation [GO:0006412]	ATP export [GO:1904669]; carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [GO:0000433]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; macroautophagy [GO:0016236]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	cell-cell junction [GO:0005911]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; vesicle [GO:0031982]	cell [GO:0005623]; ESCRT II complex [GO:0000814]; late endosome membrane [GO:0031902]	14-3-3 protein binding [GO:0071889]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein phosphatase 2A binding [GO:0051721]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]	metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266]; ubiquitin binding [GO:0043130]
d2uzwe__d2oxxa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; nucleus [GO:0005634]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]	cytosol [GO:0005829]; nucleus [GO:0005634]; protein kinase CK2 complex [GO:0005956]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; regulation of cell cycle [GO:0051726]	negative regulation of cAMP-dependent protein kinase activity [GO:2000480]	peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; regulation of cell cycle [GO:0051726]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; nucleus [GO:0005634]; protein kinase CK2 complex [GO:0005956]	cAMP-dependent protein kinase inhibitor activity [GO:0004862]	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]
d2uzxa1_d1d0ba___1	Metazoa		Chordata	Firmicutes	basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; hepatocyte growth factor-activated receptor activity [GO:0005008]; identical protein binding [GO:0042802]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; semaphorin receptor activity [GO:0017154]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; branching morphogenesis of an epithelial tube [GO:0048754]; cell surface receptor signaling pathway [GO:0007166]; endothelial cell morphogenesis [GO:0001886]; entry of bacterium into host cell [GO:0035635]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of autophagy [GO:0010507]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	branching morphogenesis of an epithelial tube [GO:0048754]; cell surface receptor signaling pathway [GO:0007166]; endothelial cell morphogenesis [GO:0001886]; entry of bacterium into host cell [GO:0035635]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of autophagy [GO:0010507]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	pathogenesis [GO:0009405]	basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; hepatocyte growth factor-activated receptor activity [GO:0005008]; identical protein binding [GO:0042802]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; semaphorin receptor activity [GO:0017154]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d2uzxc1_d1jl5a___1	Metazoa		Chordata	Proteobacteria	basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; hepatocyte growth factor-activated receptor activity [GO:0005008]; identical protein binding [GO:0042802]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; semaphorin receptor activity [GO:0017154]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; branching morphogenesis of an epithelial tube [GO:0048754]; cell surface receptor signaling pathway [GO:0007166]; endothelial cell morphogenesis [GO:0001886]; entry of bacterium into host cell [GO:0035635]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of autophagy [GO:0010507]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]	branching morphogenesis of an epithelial tube [GO:0048754]; cell surface receptor signaling pathway [GO:0007166]; endothelial cell morphogenesis [GO:0001886]; entry of bacterium into host cell [GO:0035635]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of autophagy [GO:0010507]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]	ATP binding [GO:0005524]; hepatocyte growth factor-activated receptor activity [GO:0005008]; identical protein binding [GO:0042802]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; semaphorin receptor activity [GO:0017154]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	metal ion binding [GO:0046872]
d2v00a__d5kr1b___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d2v0ha2_d3gvdh1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	serine O-acetyltransferase activity [GO:0009001]
d2v0ia1_d3st8a1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]; adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]
d2v0ia2_d1yp3b1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	amyloplast [GO:0009501]; chloroplast [GO:0009507]; ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]; glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	glycogen biosynthetic process [GO:0005978]; starch biosynthetic process [GO:0019252]	cytoplasm [GO:0005737]	amyloplast [GO:0009501]; chloroplast [GO:0009507]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	ATP binding [GO:0005524]; glucose-1-phosphate adenylyltransferase activity [GO:0008878]
d2v0ja1_d2bvma___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	host cell plasma membrane [GO:0020002]; cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	pathogenesis [GO:0009405]	cytoplasm [GO:0005737]	host cell plasma membrane [GO:0020002]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]
d2v0ja2_d1krrb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]; lactose biosynthetic process [GO:0005989]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	lactose biosynthetic process [GO:0005989]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]
d2v0ka1_d4ee3c___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cytoplasm [GO:0005737]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d2v0nb1_d1ceya___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d2v0nb1_d3w9sa___1			Proteobacteria		cytoplasm [GO:0005737]; diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]		cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]		cytoplasm [GO:0005737]		diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]	
d2v0nb2_d4h60a1__1			Proteobacteria		cytoplasm [GO:0005737]; diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]		cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]		cytoplasm [GO:0005737]		diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]	
d2v0ra__d2imqx___1	Metazoa	Metazoa	Chordata	Arthropoda	metal ion binding [GO:0046872]; RNA-directed DNA polymerase activity [GO:0003964]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197]	extracellular space [GO:0005615]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide transport [GO:0030185]; phosphatidylinositol dephosphorylation [GO:0046856]; vasodilation in other organism [GO:0044552]	DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197]	nitric oxide transport [GO:0030185]; phosphatidylinositol dephosphorylation [GO:0046856]; vasodilation in other organism [GO:0044552]		extracellular space [GO:0005615]	metal ion binding [GO:0046872]; RNA-directed DNA polymerase activity [GO:0003964]; type II site-specific deoxyribonuclease activity [GO:0009036]	heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2v0rb__d3g0aa1__1	Metazoa		Chordata	Euryarchaeota	metal ion binding [GO:0046872]; RNA-directed DNA polymerase activity [GO:0003964]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197]	DNA repair [GO:0006281]			metal ion binding [GO:0046872]; RNA-directed DNA polymerase activity [GO:0003964]; type II site-specific deoxyribonuclease activity [GO:0009036]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d2v15c__d2yjkk___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d2v15d__d3ge4b___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2v15g__d3oj5x___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d2v15j__d3ghqi___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2v15k__d5hjhb___1			Firmicutes	Cyanobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2v18f__d2cc6a___1			Deinococcus-Thermus	Euryarchaeota	nucleotide binding [GO:0000166]	cytosol [GO:0005829]				cytosol [GO:0005829]	nucleotide binding [GO:0000166]	
d2v18g__d2vxag___1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2v18i__d3oqtp___1			Deinococcus-Thermus	Actinobacteria	nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2v19a1_d3oqtl___1			Deinococcus-Thermus	Actinobacteria	nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2v19e__d2yj0e___1			Deinococcus-Thermus	Actinobacteria	nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2v19g__d3oqtn___1			Deinococcus-Thermus	Actinobacteria	nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2v19h__d2vxad___1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2v19j__d2vxaj___1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2v1fa__d1j41f___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2v1ha__d1hgad___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2v1oa__d3ed0a___1	Metazoa		Chordata	Proteobacteria	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; fatty-acyl-CoA binding [GO:0000062]; identical protein binding [GO:0042802]; long-chain fatty acyl-CoA binding [GO:0036042]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290]; protein homodimerization activity [GO:0042803]; acyl-CoA metabolic process [GO:0006637]; coenzyme A biosynthetic process [GO:0015937]; fatty acid catabolic process [GO:0009062]; long-chain fatty-acyl-CoA catabolic process [GO:0036116]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; palmitic acid biosynthetic process [GO:1900535]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	acyl-CoA metabolic process [GO:0006637]; coenzyme A biosynthetic process [GO:0015937]; fatty acid catabolic process [GO:0009062]; long-chain fatty-acyl-CoA catabolic process [GO:0036116]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; palmitic acid biosynthetic process [GO:1900535]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; fatty-acyl-CoA binding [GO:0000062]; identical protein binding [GO:0042802]; long-chain fatty acyl-CoA binding [GO:0036042]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290]; protein homodimerization activity [GO:0042803]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d2v1oc__d3ed0b___1	Metazoa		Chordata	Proteobacteria	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; fatty-acyl-CoA binding [GO:0000062]; identical protein binding [GO:0042802]; long-chain fatty acyl-CoA binding [GO:0036042]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290]; protein homodimerization activity [GO:0042803]; acyl-CoA metabolic process [GO:0006637]; coenzyme A biosynthetic process [GO:0015937]; fatty acid catabolic process [GO:0009062]; long-chain fatty-acyl-CoA catabolic process [GO:0036116]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; palmitic acid biosynthetic process [GO:1900535]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	acyl-CoA metabolic process [GO:0006637]; coenzyme A biosynthetic process [GO:0015937]; fatty acid catabolic process [GO:0009062]; long-chain fatty-acyl-CoA catabolic process [GO:0036116]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; palmitic acid biosynthetic process [GO:1900535]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; fatty-acyl-CoA binding [GO:0000062]; identical protein binding [GO:0042802]; long-chain fatty acyl-CoA binding [GO:0036042]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290]; protein homodimerization activity [GO:0042803]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d2v21e__d2vxaa___1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2v21f__d3oqti___1			Deinococcus-Thermus	Actinobacteria	nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2v23a__d5ksfb1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2v29a__d2v9gc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]
d2v29b__d2uyvc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]
d2v2ca__d4unlb___1		Metazoa		Chordata	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	triose-phosphate isomerase activity [GO:0004807]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]
d2v2ha__d1w0mb___1				Crenarchaeota	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytoplasm [GO:0005737]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2v2la__d2jd7u___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]
d2v2la__d5d8rc___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2v2na__d3qd8x1__1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2v2na__d5xhia___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2v2oa__d4ii4c1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cytosol [GO:0005829]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	
d2v2tb1_d4pygb1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d2v2ua2_d2jdga1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; camera-type eye development [GO:0043010]; eye development [GO:0001654]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; lens fiber cell morphogenesis [GO:0070309]; visual perception [GO:0007601]	camera-type eye development [GO:0043010]; eye development [GO:0001654]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]	lens development in camera-type eye [GO:0002088]; lens fiber cell morphogenesis [GO:0070309]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	structural constituent of eye lens [GO:0005212]	structural constituent of eye lens [GO:0005212]
d2v2wb2_d1h8sb2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2v2wd1_d3m1be2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2v2wd2_d1sebb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d2v2xa1_d2r2ha1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]
d2v2xb2_d1yuhl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2v2xe2_d1bqhe___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2v2xe2_d2igfh1__1	Metazoa	Metazoa	Chordata	Annelida	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]
d2v32a__d3i69d1__1	Metazoa	Metazoa	Annelida	Chordata	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	peroxiredoxin activity [GO:0051920]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2v33a__d2bzda2__1				Actinobacteria	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	metabolic process [GO:0008152]	host cell endosome [GO:0044174]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d2v37a__d4zmvb1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d2v3db2_d3f55d___1	Metazoa		Chordata		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	
d2v3db2_d4flra1__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	extracellular region [GO:0005576]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	amylosucrase activity [GO:0047669]
d2v3eb2_d2d20a1__1	Metazoa		Chordata	Actinobacteria	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	polysaccharide catabolic process [GO:0000272]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	endo-1,4-beta-xylanase activity [GO:0031176]
d2v3fa2_d1uh3a3__1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	extracellular region [GO:0005576]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2v3fb2_d4nrsa1__1	Metazoa	Fungi	Chordata	Mucoromycota	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	beta-mannosidase activity [GO:0004567]; metabolic process [GO:0008152]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	metabolic process [GO:0008152]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	beta-mannosidase activity [GO:0004567]
d2v3wb3_d1ybha3__1		Viridiplantae	Proteobacteria	Streptophyta	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	mandelate catabolic process [GO:0019596]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2v3wc1_d2wvae2__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2v3wc3_d2g25b2__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	mandelate catabolic process [GO:0019596]	glycolytic process [GO:0006096]		cytosol [GO:0005829]; membrane [GO:0016020]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]
d2v3wd3_d1t9ba2__1		Fungi	Proteobacteria	Ascomycota	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mandelate catabolic process [GO:0019596]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2v41a__d4ofmb1__1	Metazoa	Metazoa	Annelida	Nematoda (roundworms)	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	transferase activity [GO:0016740]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]		peroxiredoxin activity [GO:0051920]	transferase activity [GO:0016740]
d2v41d__d3tkrh___1	Metazoa	Metazoa	Annelida	Chordata	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	peroxiredoxin activity [GO:0051920]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d2v41e__d4hj2a1__1	Metazoa	Metazoa	Annelida	Chordata	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	peroxiredoxin activity [GO:0051920]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2v41f__d1oe7a2__1	Metazoa	Metazoa	Annelida	Platyhelminthes	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]		peroxiredoxin activity [GO:0051920]	glutathione transferase activity [GO:0004364]
d2v41f__d3hvsa___1	Metazoa		Annelida	Proteobacteria	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	peroxiredoxin activity [GO:0051920]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]
d2v44a1_d2fjfe1__1												
d2v45a1_d3hu2c1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	periplasmic space [GO:0042597]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d2v46f1_d1vs5f1__1												
d2v46t1_d2qoyt1__1												
d2v47e1_d3u6ka2__1				Actinobacteria		extracellular region [GO:0005576]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]		cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]		extracellular region [GO:0005576]		
d2v47n1_d3df2j1__1												
d2v47u1_d2zjqn1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2v47y1_d1vqnt1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2v48k1_d2vhpk1__1												
d2v48r1_d1i94r___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2v48t1_d2ow8u1__1												
d2v49e1_d3cw2b2__1				Crenarchaeota		cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d2v49t1_d2zjrm1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2v4ja2_d4g39a3__1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	sulfite reductase complex (NADPH) [GO:0009337]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	sulfur compound metabolic process [GO:0006790]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]		sulfite reductase complex (NADPH) [GO:0009337]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]
d2v4jd1_d3mm8d3__1			Proteobacteria	Euryarchaeota	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	sulfur compound metabolic process [GO:0006790]	sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d2v4jd2_d3mmbe1__1			Proteobacteria	Euryarchaeota	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	sulfur compound metabolic process [GO:0006790]	sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d2v4jd2_d3vkra1__1		Viridiplantae	Proteobacteria	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfur compound metabolic process [GO:0006790]				4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2v4je2_d7gepa1__1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	sulfite reductase complex (NADPH) [GO:0009337]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	sulfur compound metabolic process [GO:0006790]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]		sulfite reductase complex (NADPH) [GO:0009337]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]
d2v4ma__d2decb___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; circadian regulation of gene expression [GO:0032922]; energy reserve metabolic process [GO:0006112]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; IRE1-mediated unfolded protein response [GO:0036498]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	carbohydrate derivative binding [GO:0097367]; carbohydrate derivative metabolic process [GO:1901135]	circadian regulation of gene expression [GO:0032922]; energy reserve metabolic process [GO:0006112]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; IRE1-mediated unfolded protein response [GO:0036498]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	carbohydrate derivative metabolic process [GO:1901135]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	carbohydrate derivative binding [GO:0097367]
d2v4mc__d2cxua___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; circadian regulation of gene expression [GO:0032922]; energy reserve metabolic process [GO:0006112]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; IRE1-mediated unfolded protein response [GO:0036498]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	circadian regulation of gene expression [GO:0032922]; energy reserve metabolic process [GO:0006112]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; IRE1-mediated unfolded protein response [GO:0036498]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d2v4md__d2j6ha1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; circadian regulation of gene expression [GO:0032922]; energy reserve metabolic process [GO:0006112]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; IRE1-mediated unfolded protein response [GO:0036498]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	circadian regulation of gene expression [GO:0032922]; energy reserve metabolic process [GO:0006112]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; IRE1-mediated unfolded protein response [GO:0036498]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]
d2v4oc1_d4xj7c1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3'-nucleotidase activity [GO:0008254]; 5'-nucleotidase activity [GO:0008253]; exopolyphosphatase activity [GO:0004309]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UMP catabolic process [GO:0046050]	cytoplasm [GO:0005737]; 3'-nucleotidase activity [GO:0008254]; 5'-nucleotidase activity [GO:0008253]; exopolyphosphatase activity [GO:0004309]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UMP catabolic process [GO:0046050]	UMP catabolic process [GO:0046050]	UMP catabolic process [GO:0046050]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3'-nucleotidase activity [GO:0008254]; 5'-nucleotidase activity [GO:0008253]; exopolyphosphatase activity [GO:0004309]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3'-nucleotidase activity [GO:0008254]; 5'-nucleotidase activity [GO:0008253]; exopolyphosphatase activity [GO:0004309]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2v4sa2_d1jihb1__1		Fungi		Ascomycota		mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]		chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]		mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]		damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d2v4va__d1jyyd3__1			Firmicutes		carbohydrate binding [GO:0030246]; galactosylceramidase activity [GO:0004336]; galactosylceramide catabolic process [GO:0006683]; polysaccharide catabolic process [GO:0000272]		galactosylceramide catabolic process [GO:0006683]; polysaccharide catabolic process [GO:0000272]				carbohydrate binding [GO:0030246]; galactosylceramidase activity [GO:0004336]	
d2v54a__d5jhhf___1		Metazoa		Chordata	ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]		apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d2v58a2_d2r87b2__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]
d2v5aa1_d1bxra3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2v5aa3_d2c00a3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2v5ca1_d4c7fa1__1			Firmicutes	Actinobacteria	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	beta-N-acetylhexosaminidase activity [GO:0004563]
d2v5hb__d1uvdk___1			Cyanobacteria		enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; regulation of nitrogen utilization [GO:0006808]		regulation of nitrogen utilization [GO:0006808]				enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	
d2v5hd__d2we4c___1			Cyanobacteria	Firmicutes	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; regulation of nitrogen utilization [GO:0006808]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]; arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	regulation of nitrogen utilization [GO:0006808]	arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]		cytoplasm [GO:0005737]	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]
d2v5hf__d3ek5d___1			Cyanobacteria	Proteobacteria	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; regulation of nitrogen utilization [GO:0006808]	cytosol [GO:0005829]; ATP binding [GO:0005524]; UMP kinase activity [GO:0033862]; 'de novo' CTP biosynthetic process [GO:0044210]; UDP biosynthetic process [GO:0006225]	regulation of nitrogen utilization [GO:0006808]	'de novo' CTP biosynthetic process [GO:0044210]; UDP biosynthetic process [GO:0006225]		cytosol [GO:0005829]	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; UMP kinase activity [GO:0033862]
d2v5hh__d3opka___1			Cyanobacteria	Proteobacteria	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; regulation of nitrogen utilization [GO:0006808]	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; response to metal ion [GO:0010038]	regulation of nitrogen utilization [GO:0006808]	response to metal ion [GO:0010038]		cytoplasm [GO:0005737]	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	copper ion binding [GO:0005507]
d2v5hj__d3ah6c___1			Cyanobacteria	Proteobacteria	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; regulation of nitrogen utilization [GO:0006808]	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; metal ion binding [GO:0046872]; protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	regulation of nitrogen utilization [GO:0006808]	protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]		cytoplasm [GO:0005737]	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	copper ion binding [GO:0005507]; metal ion binding [GO:0046872]
d2v5ua__d1akra___1			Cyanobacteria	Proteobacteria	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]		cell [GO:0005623]		electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2v5ua__d1h66d___1		Metazoa	Cyanobacteria	Chordata	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d2v60a2_d1pbfa2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d2v61a2_d1h83c2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]
d2v61a2_d3gyja2__1	Metazoa		Chordata	Actinobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cholesterol metabolic process [GO:0008203]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]
d2v61b2_d2phha2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d2v63j__d4hhhs___1	Viridiplantae	Viridiplantae	Chlorophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2v63n__d1upmp___1	Viridiplantae	Viridiplantae	Chlorophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2v65a2_d4okna2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-lactate dehydrogenase activity [GO:0004459]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2v67l__d3axmx___1	Viridiplantae	Viridiplantae	Chlorophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2v69j__d1rxoc___1	Viridiplantae	Viridiplantae	Chlorophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2v69m__d4rubu___1	Viridiplantae	Viridiplantae	Chlorophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2v6ma2_d4l4sh2__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-lactate dehydrogenase activity [GO:0004459]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2v6mb2_d4bgvb2__1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]
d2v70d__d2xwtc___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; GTPase inhibitor activity [GO:0005095]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; laminin-1 binding [GO:0043237]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; Roundabout binding [GO:0048495]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; cellular response to hormone stimulus [GO:0032870]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; induction of negative chemotaxis [GO:0050929]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; pulmonary valve morphogenesis [GO:0003184]; response to cortisol [GO:0051414]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]; activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; cellular response to hormone stimulus [GO:0032870]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; induction of negative chemotaxis [GO:0050929]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; pulmonary valve morphogenesis [GO:0003184]; response to cortisol [GO:0051414]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	calcium ion binding [GO:0005509]; GTPase inhibitor activity [GO:0005095]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; laminin-1 binding [GO:0043237]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; Roundabout binding [GO:0048495]	G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]
d2v76d__d2iybd___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; macrophage colony-stimulating factor signaling pathway [GO:0038145]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell junction [GO:0030054]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; negative regulation of cell population proliferation [GO:0008285]	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; macrophage colony-stimulating factor signaling pathway [GO:0038145]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	negative regulation of cell population proliferation [GO:0008285]	cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cell junction [GO:0030054]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		cadherin binding [GO:0045296]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2v78b__d1lhpb___1		Metazoa	Crenarchaeota	Chordata	2-dehydro-3-deoxygalactonokinase activity [GO:0008671]; 2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]; pyridoxal 5'-phosphate salvage [GO:0009443]	phosphorylation [GO:0016310]	pyridoxal 5'-phosphate salvage [GO:0009443]		cytoplasm [GO:0005737]	2-dehydro-3-deoxygalactonokinase activity [GO:0008671]; 2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]
d2v78b__d5byda1__1		Metazoa	Crenarchaeota	Chordata	2-dehydro-3-deoxygalactonokinase activity [GO:0008671]; 2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]; phosphorylation [GO:0016310]	cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]	phosphorylation [GO:0016310]	D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]		cytosol [GO:0005829]; nucleus [GO:0005634]	2-dehydro-3-deoxygalactonokinase activity [GO:0008671]; 2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d2v78c__d5ey7b___1			Crenarchaeota	Proteobacteria	2-dehydro-3-deoxygalactonokinase activity [GO:0008671]; 2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]; phosphorylation [GO:0016310]	fructokinase activity [GO:0008865]; nucleotide binding [GO:0000166]	phosphorylation [GO:0016310]				2-dehydro-3-deoxygalactonokinase activity [GO:0008671]; 2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]	fructokinase activity [GO:0008865]; nucleotide binding [GO:0000166]
d2v7ha1_d5c9ka1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2v7hb3_d5kvll1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2v7hl1_d5kani2__1	Metazoa		Chordata	Negarnaviricota	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	host cell surface receptor binding [GO:0046789]
d2v7na1_d4whtd2__1						viral envelope [GO:0019031]				viral envelope [GO:0019031]		
d2v7na2_d1mcpl1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2v7nc1_d5d7jh1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2v7ne1_d1py9a___1		Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]		signaling receptor binding [GO:0005102]
d2v7ne1_d4unva___1		Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d2v7pa1_d1up7g1__1			Deinococcus-Thermus	Thermotogae	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d2v7pb2_d4ajod2__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2v7pd2_d3wswd2__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d2v7pd2_d4ajia2__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2v7qd1_d5hkkf1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2v7qe1_d2jj1c1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2v7qe2_d1ny6b___1	Metazoa		Chordata	Aquificae	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	ATP synthesis coupled proton transport [GO:0015986]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d2v7qf3_d1fx0b1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2v7ta2_d2c2wb2__1			Actinobacteria	Actinobacteria	adenosyl-fluoride synthase activity [GO:0033846]	adenosyl-fluoride synthase activity [GO:0033846]					adenosyl-fluoride synthase activity [GO:0033846]	adenosyl-fluoride synthase activity [GO:0033846]
d2v7ua1_d2q6oa2__1			Actinobacteria	Actinobacteria	adenosyl-fluoride synthase activity [GO:0033846]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]					adenosyl-fluoride synthase activity [GO:0033846]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]
d2v7ub2_d2c4tb2__1			Actinobacteria	Actinobacteria	adenosyl-fluoride synthase activity [GO:0033846]	adenosyl-fluoride synthase activity [GO:0033846]					adenosyl-fluoride synthase activity [GO:0033846]	adenosyl-fluoride synthase activity [GO:0033846]
d2v7va2_d2q6ia1__1			Actinobacteria	Actinobacteria	adenosyl-fluoride synthase activity [GO:0033846]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]					adenosyl-fluoride synthase activity [GO:0033846]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]
d2v7vb2_d2q6oa1__1			Actinobacteria	Actinobacteria	adenosyl-fluoride synthase activity [GO:0033846]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]					adenosyl-fluoride synthase activity [GO:0033846]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]
d2v7wa2_d2q6la1__1			Actinobacteria	Actinobacteria	adenosyl-fluoride synthase activity [GO:0033846]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]					adenosyl-fluoride synthase activity [GO:0033846]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]
d2v7xc2_d2c4ua2__1			Actinobacteria	Actinobacteria	adenosyl-fluoride synthase activity [GO:0033846]	adenosyl-fluoride synthase activity [GO:0033846]					adenosyl-fluoride synthase activity [GO:0033846]	adenosyl-fluoride synthase activity [GO:0033846]
d2v7xc2_d2q6ka1__1			Actinobacteria	Actinobacteria	adenosyl-fluoride synthase activity [GO:0033846]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]					adenosyl-fluoride synthase activity [GO:0033846]	transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]
d2v84a__d3e3kc___1			Spirochaetes	Proteobacteria	periplasmic space [GO:0042597]; polyamine binding [GO:0019808]; polyamine transport [GO:0015846]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	polyamine transport [GO:0015846]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	polyamine binding [GO:0019808]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]
d2v8ba__d4ne7a___1	Fungi		Ascomycota	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2v8ca__d3dava___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; postsynapse [GO:0098794]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; terminal bouton [GO:0043195]; actin binding [GO:0003779]; actin monomer binding [GO:0003785]; ATPase activity [GO:0016887]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; actin cytoskeleton organization [GO:0030036]; modification of postsynaptic actin cytoskeleton [GO:0098885]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ruffle assembly [GO:1900028]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of ATPase activity [GO:0032781]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of stress fiber assembly [GO:0051496]; protein stabilization [GO:0050821]; regulation of actin filament polymerization [GO:0030833]; regulation of synaptic vesicle exocytosis [GO:2000300]	actin cortical patch [GO:0030479]; cell [GO:0005623]; cell cortex [GO:0005938]; cell cortex of cell tip [GO:0051285]; mating projection tip [GO:0043332]; medial cortex [GO:0031097]; actin monomer binding [GO:0003785]; guanyl-nucleotide exchange factor activity [GO:0005085]; actin cortical patch organization [GO:0044396]; actin filament polymerization [GO:0030041]; cytogamy [GO:0000755]; mitotic actomyosin contractile ring assembly [GO:1903475]; negative regulation of actin filament binding [GO:1904530]; negative regulation of actin filament polymerization [GO:0030837]; regulation of barbed-end actin filament capping [GO:2000812]; sequestering of actin monomers [GO:0042989]	actin cytoskeleton organization [GO:0030036]; modification of postsynaptic actin cytoskeleton [GO:0098885]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ruffle assembly [GO:1900028]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of ATPase activity [GO:0032781]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of stress fiber assembly [GO:0051496]; protein stabilization [GO:0050821]; regulation of actin filament polymerization [GO:0030833]; regulation of synaptic vesicle exocytosis [GO:2000300]	actin cortical patch organization [GO:0044396]; actin filament polymerization [GO:0030041]; cytogamy [GO:0000755]; mitotic actomyosin contractile ring assembly [GO:1903475]; negative regulation of actin filament binding [GO:1904530]; negative regulation of actin filament polymerization [GO:0030837]; regulation of barbed-end actin filament capping [GO:2000812]; sequestering of actin monomers [GO:0042989]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; postsynapse [GO:0098794]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; terminal bouton [GO:0043195]	actin cortical patch [GO:0030479]; cell [GO:0005623]; cell cortex [GO:0005938]; cell cortex of cell tip [GO:0051285]; mating projection tip [GO:0043332]; medial cortex [GO:0031097]	actin binding [GO:0003779]; actin monomer binding [GO:0003785]; ATPase activity [GO:0016887]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]	actin monomer binding [GO:0003785]; guanyl-nucleotide exchange factor activity [GO:0005085]
d2v8ua__d1o9id___1			Deinococcus-Thermus	Firmicutes	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]					catalase activity [GO:0004096]; metal ion binding [GO:0046872]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]
d2v8ub__d3bvle1__1			Deinococcus-Thermus	Proteobacteria	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d2v8za__d2wo5c___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]; aldonic acid catabolic process [GO:0046176]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	aldonic acid catabolic process [GO:0046176]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d2v90a__d2vrfc1__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytosol [GO:0005829]; subapical complex [GO:0035003]; guanylate cyclase inhibitor activity [GO:0030251]; ion channel inhibitor activity [GO:0008200]; protein C-terminus binding [GO:0008022]; ubiquitin-specific protease binding [GO:1990381]; ion transport [GO:0006811]; negative regulation of cGMP-mediated signaling [GO:0010754]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to toxic substance [GO:0009636]; water transport [GO:0006833]	cytoplasm [GO:0005737]; dystrophin-associated glycoprotein complex [GO:0016010]; focal adhesion [GO:0005925]; membrane [GO:0016020]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	ion transport [GO:0006811]; negative regulation of cGMP-mediated signaling [GO:0010754]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to toxic substance [GO:0009636]; water transport [GO:0006833]		apical part of cell [GO:0045177]; brush border [GO:0005903]; cytosol [GO:0005829]; subapical complex [GO:0035003]	cytoplasm [GO:0005737]; dystrophin-associated glycoprotein complex [GO:0016010]; focal adhesion [GO:0005925]; membrane [GO:0016020]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658]	guanylate cyclase inhibitor activity [GO:0030251]; ion channel inhibitor activity [GO:0008200]; protein C-terminus binding [GO:0008022]; ubiquitin-specific protease binding [GO:1990381]	actin binding [GO:0003779]; calmodulin binding [GO:0005516]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d2v90b__d1be9a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytosol [GO:0005829]; subapical complex [GO:0035003]; guanylate cyclase inhibitor activity [GO:0030251]; ion channel inhibitor activity [GO:0008200]; protein C-terminus binding [GO:0008022]; ubiquitin-specific protease binding [GO:1990381]; ion transport [GO:0006811]; negative regulation of cGMP-mediated signaling [GO:0010754]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to toxic substance [GO:0009636]; water transport [GO:0006833]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	ion transport [GO:0006811]; negative regulation of cGMP-mediated signaling [GO:0010754]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to toxic substance [GO:0009636]; water transport [GO:0006833]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	apical part of cell [GO:0045177]; brush border [GO:0005903]; cytosol [GO:0005829]; subapical complex [GO:0035003]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	guanylate cyclase inhibitor activity [GO:0030251]; ion channel inhibitor activity [GO:0008200]; protein C-terminus binding [GO:0008022]; ubiquitin-specific protease binding [GO:1990381]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]
d2v9nc__d1gt7i___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	cytosol [GO:0005829]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]
d2v9oe__d4c24a1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]; pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]	L-fuculose-phosphate aldolase activity [GO:0008738]; metal ion binding [GO:0046872]	pentose catabolic process [GO:0019323]; rhamnose catabolic process [GO:0019301]		cytosol [GO:0005829]		aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; rhamnulose-1-phosphate aldolase activity [GO:0008994]	L-fuculose-phosphate aldolase activity [GO:0008738]; metal ion binding [GO:0046872]
d2v9ra2_d1jpsl2__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	activation of blood coagulation via clotting cascade [GO:0002543]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of plasma proteins involved in acute inflammatory response [GO:0002541]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; cytokine-mediated signaling pathway [GO:0019221]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]	axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]	cytokine receptor activity [GO:0004896]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]
d2v9tb__d2wqub1__1	Metazoa		Chordata	Firmicutes	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	pathogenesis [GO:0009405]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]	heparin binding [GO:0008201]; lipid binding [GO:0008289]
d2v9xa__d3hhqe___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2v9xh__d4aooa___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]		dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2v9xi__d3c2tb___1			Proteobacteria		cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]		dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2v9xk__d3hhqm___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2v9xk__d4a6ag___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]		dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d2va4a1_d5czvl2__1		Metazoa		Chordata		actin cytoskeleton [GO:0015629]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; signaling receptor activity [GO:0038023]; artery morphogenesis [GO:0048844]; forebrain development [GO:0030900]; glomerular capillary formation [GO:0072104]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron fate commitment [GO:0048663]; Notch signaling pathway [GO:0007219]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription of Notch receptor target [GO:0007221]; transcription initiation from RNA polymerase II promoter [GO:0006367]		artery morphogenesis [GO:0048844]; forebrain development [GO:0030900]; glomerular capillary formation [GO:0072104]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron fate commitment [GO:0048663]; Notch signaling pathway [GO:0007219]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription of Notch receptor target [GO:0007221]; transcription initiation from RNA polymerase II promoter [GO:0006367]		actin cytoskeleton [GO:0015629]; cell surface [GO:0009986]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; signaling receptor activity [GO:0038023]
d2vaaa1_d1zwib1__1	Metazoa		Chordata	Actinobacteria	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	voltage-gated potassium channel complex [GO:0008076]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d2vaab__d3c6sc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2vaab__d4od1l2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2vaba1_d1h0db1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]
d2vabb__d2q7yb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2vabb__d4pjaf1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2vaob2_d3nrzb1__1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	methanol metabolic process [GO:0015945]	xanthine catabolic process [GO:0009115]	peroxisome [GO:0005777]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d2vaua__d1gp5a___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]; penicillin biosynthetic process [GO:0042318]	dioxygenase activity [GO:0051213]; L-ascorbic acid binding [GO:0031418]; leucocyanidin oxygenase activity [GO:0050589]; metal ion binding [GO:0046872]; anthocyanin-containing compound biosynthetic process [GO:0009718]; proanthocyanidin biosynthetic process [GO:0010023]; response to jasmonic acid [GO:0009753]; response to wounding [GO:0009611]; vacuole organization [GO:0007033]	penicillin biosynthetic process [GO:0042318]	anthocyanin-containing compound biosynthetic process [GO:0009718]; proanthocyanidin biosynthetic process [GO:0010023]; response to jasmonic acid [GO:0009753]; response to wounding [GO:0009611]; vacuole organization [GO:0007033]			dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]	dioxygenase activity [GO:0051213]; L-ascorbic acid binding [GO:0031418]; leucocyanidin oxygenase activity [GO:0050589]; metal ion binding [GO:0046872]
d2vb7a1_d5wc4a1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biphenyl synthase activity [GO:0033815]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	biphenyl synthase activity [GO:0033815]
d2vb7a2_d4o99b1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2vb7b2_d2gyob2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2vb7c2_d1h4fb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2vb8a2_d2qo0b2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d2vb8a2_d2wktc1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2vb8b2_d4dfed2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2vb8d1_d1ox0a1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d2vb8d1_d5wx5a2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2vb8d2_d1m4ta2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2vb9a1_d1i8bb2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	naringenin-chalcone synthase activity [GO:0016210]
d2vb9b1_d1tqye2__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2vb9b1_d4n44a2__1			Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	
d2vb9b2_d4ewgb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	transferase activity [GO:0016740]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity [GO:0016740]
d2vb9d1_d2wkvd1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2vb9d2_d2bywc2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2vbab1_d1og9c4__1			Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	
d2vbab1_d4ewga1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	transferase activity [GO:0016740]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity [GO:0016740]
d2vbab2_d1m1tc2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2vbab2_d3a5qa1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]; protein-chromophore linkage [GO:0018298]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	flavonoid biosynthetic process [GO:0009813]; protein-chromophore linkage [GO:0018298]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2vbad1_d1fj8b2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2vbad1_d3kzub1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d2vbda__d5ph2a___1	Fungi	Metazoa	Ascomycota	Chordata	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]; penicillin biosynthetic process [GO:0042318]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	penicillin biosynthetic process [GO:0042318]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]		blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d2vbja__d2o7ma___1	Viridiplantae	Viridiplantae	Chlorophyta	Chlorophyta	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]	intron homing [GO:0006314]	intron homing [GO:0006314]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2vbnb__d1t9ia___1	Viridiplantae	Viridiplantae	Chlorophyta	Chlorophyta	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]	intron homing [GO:0006314]	intron homing [GO:0006314]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2vbob__d1ef0a3__1	Viridiplantae	Fungi	Chlorophyta	Ascomycota	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	intron homing [GO:0006314]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	chloroplast [GO:0009507]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]
d2vbqa2_d4cawa1__1		Fungi	Proteobacteria	Ascomycota	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]; protein homodimerization activity [GO:0042803]; acetyl-CoA metabolic process [GO:0006084]; histone acetylation [GO:0016573]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]	acetyl-CoA metabolic process [GO:0006084]; histone acetylation [GO:0016573]; response to antibiotic [GO:0046677]	N-terminal peptidyl-glycine N-myristoylation [GO:0018008]		cytoplasm [GO:0005737]	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]; protein homodimerization activity [GO:0042803]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d2vbqb__d5dwmb___1			Proteobacteria	Proteobacteria	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]; protein homodimerization activity [GO:0042803]; acetyl-CoA metabolic process [GO:0006084]; histone acetylation [GO:0016573]; response to antibiotic [GO:0046677]	N-acetyltransferase activity [GO:0008080]	acetyl-CoA metabolic process [GO:0006084]; histone acetylation [GO:0016573]; response to antibiotic [GO:0046677]				aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]; protein homodimerization activity [GO:0042803]	N-acetyltransferase activity [GO:0008080]
d2vc2a__d3vi3a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integrin alpha5-beta1 complex [GO:0034674]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]; epidermal growth factor receptor binding [GO:0005154]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor receptor binding [GO:0005161]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; angiogenesis [GO:0001525]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory [GO:0007613]; negative regulation of anoikis [GO:2000811]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	angiogenesis [GO:0001525]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory [GO:0007613]; negative regulation of anoikis [GO:2000811]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; wound healing, spreading of epidermal cells [GO:0035313]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integrin alpha5-beta1 complex [GO:0034674]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	epidermal growth factor receptor binding [GO:0005154]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor receptor binding [GO:0005161]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]
d2vc4a__d4zfya___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2vcfx2_d5ejta___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	chloroplast [GO:0009507]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2vcqa2_d2eirb___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2vcqb2_d5dbqb___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cell [GO:0005623]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	protein disulfide oxidoreductase activity [GO:0015035]
d2vcrb1_d1xbsa___1		Metazoa		Chordata		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; cell cycle [GO:0007049]; mRNA splicing, via spliceosome [GO:0000398]		cell cycle [GO:0007049]; mRNA splicing, via spliceosome [GO:0000398]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		
d2vcrc2_d1xw6d1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d2vcrd2_d4deji2__1				Proteobacteria		transferase activity [GO:0016740]						transferase activity [GO:0016740]
d2vcre1_d1gsqa2__1		Metazoa		Mollusca		cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]				cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]
d2vcrf1_d4yqua1__1		Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]		cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d2vcrf2_d3zmlb2__1		Metazoa		Arthropoda		transferase activity [GO:0016740]						transferase activity [GO:0016740]
d2vcsa__d4m11d2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	chloroplast [GO:0009507]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d2vcta1_d5dvbd1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to oxidative stress [GO:0006979]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutathione transferase activity [GO:0004364]	peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]
d2vctc1_d1we0c___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2vctd2_d5an1a2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2vcte2_d2vd1d1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	glutathione transferase activity [GO:0004364]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d2vcte2_d2wdua2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2vctg1_d1okta2__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2vcth2_d5ecie2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	glutathione transferase activity [GO:0004364]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2vcva2_d2x64e2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d2vcvb2_d4ri6a2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2vcvc2_d1lbka1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2vcvd1_d5j3ra___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cis-Golgi network [GO:0005801]; endoplasmic reticulum membrane [GO:0005789]; fungal-type vacuole [GO:0000324]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; iron ion binding [GO:0005506]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cis-Golgi network [GO:0005801]; endoplasmic reticulum membrane [GO:0005789]; fungal-type vacuole [GO:0000324]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; integral component of membrane [GO:0016021]	glutathione transferase activity [GO:0004364]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; iron ion binding [GO:0005506]; protein disulfide oxidoreductase activity [GO:0015035]
d2vcvd2_d1px6b1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2vcve1_d1xw6a2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	glutathione transferase activity [GO:0004364]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d2vcve2_d4nhzh2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d2vcvi1_d1jfua___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	glutathione transferase activity [GO:0004364]	oxidoreductase activity [GO:0016491]
d2vcvk2_d4ecba1__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2vcvl1_d2p31a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; catalase activity [GO:0004096]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cellular response to oxidative stress [GO:0034599]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]	glutathione transferase activity [GO:0004364]	catalase activity [GO:0004096]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]
d2vcvn2_d4zbda2__1	Metazoa	Fungi	Chordata	Basidiomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione transferase activity [GO:0004364]	
d2vcvo1_d1ezka1__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]	glutathione transferase activity [GO:0004364]	
d2vcwb2_d3a2wb___1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytoplasm [GO:0005737]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2vcwc2_d3ktlb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2vcxa2_d1uc7b___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	electron transfer activity [GO:0009055]; protein-disulfide reductase activity [GO:0047134]
d2vcxb1_d1tdia2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d2vcxb1_d4ofta2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	transferase activity [GO:0016740]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	transferase activity [GO:0016740]
d2vcxb2_d1gulh2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2vcza2_d3i43b___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]
d2vczc2_d4polb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d2vczd1_d3uara2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione transferase activity [GO:0004364]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d2vczd2_d1agsa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d2vd0b2_d3hjoa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2vd0c1_d1zgnb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2vd0c1_d5hfka2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	disulfide oxidoreductase activity [GO:0015036]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	disulfide oxidoreductase activity [GO:0015036]; peroxidase activity [GO:0004601]
d2vd0c2_d5jwrd___1	Metazoa		Chordata	Cyanobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	
d2vd1b2_d1fg4a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cell [GO:0005623]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	
d2vd1c2_d1vf2a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d2vd1c2_d5jcgf1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; alkyl hydroperoxide reductase activity [GO:0008785]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	alkyl hydroperoxide reductase activity [GO:0008785]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d2vd3a1_d1a7lc___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	histidine biosynthetic process [GO:0000105]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cytoplasm [GO:0005737]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d2vd4a2_d1kk5a___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	transferase activity, transferring acyl groups [GO:0016746]
d2vdba2_d4n0fg2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2vdcb3_d1mc1b2__1			Proteobacteria	Actinobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; glutamate synthase (NADPH) activity [GO:0004355]; metal ion binding [GO:0046872]; L-glutamate biosynthetic process [GO:0097054]	(carboxyethyl)arginine beta-lactam-synthase activity [GO:0034027]; asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; asparagine biosynthetic process [GO:0006529]; clavulanic acid biosynthetic process [GO:0033050]	L-glutamate biosynthetic process [GO:0097054]	asparagine biosynthetic process [GO:0006529]; clavulanic acid biosynthetic process [GO:0033050]			4 iron, 4 sulfur cluster binding [GO:0051539]; glutamate synthase (NADPH) activity [GO:0004355]; metal ion binding [GO:0046872]	(carboxyethyl)arginine beta-lactam-synthase activity [GO:0034027]; asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d2vdcf3_d5l5ot___1		Fungi	Proteobacteria	Ascomycota	4 iron, 4 sulfur cluster binding [GO:0051539]; glutamate synthase (NADPH) activity [GO:0004355]; metal ion binding [GO:0046872]; L-glutamate biosynthetic process [GO:0097054]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	L-glutamate biosynthetic process [GO:0097054]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	4 iron, 4 sulfur cluster binding [GO:0051539]; glutamate synthase (NADPH) activity [GO:0004355]; metal ion binding [GO:0046872]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2vdip__d1rcoi___1	Viridiplantae	Viridiplantae	Chlorophyta	Streptophyta	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2vdkl1_d5a16f1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	
d2vdkl2_d5kd4b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2vdml2_d1mfch1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2vdna__d3vi3c1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integrin alpha5-beta1 complex [GO:0034674]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]; epidermal growth factor receptor binding [GO:0005154]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor receptor binding [GO:0005161]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; angiogenesis [GO:0001525]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory [GO:0007613]; negative regulation of anoikis [GO:2000811]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; wound healing, spreading of epidermal cells [GO:0035313]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	angiogenesis [GO:0001525]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory [GO:0007613]; negative regulation of anoikis [GO:2000811]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; wound healing, spreading of epidermal cells [GO:0035313]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integrin alpha5-beta1 complex [GO:0034674]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	epidermal growth factor receptor binding [GO:0005154]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor receptor binding [GO:0005161]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]
d2vdsa1_d2yxwa1__1				Proteobacteria		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d2vdsa2_d3jt2b___1				Proteobacteria		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2vdza2_d1l9qa2__1				Proteobacteria		periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2vdza2_d5ehfa2__1		Fungi		Basidiomycota		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]						copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2vdza3_d4yvua3__1				Firmicutes		outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2ve0a1_d2p80b2__1				Proteobacteria		periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2ve0a2_d4yseb1__1				Proteobacteria		periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2ve1a__d5fjka___1	Fungi	Metazoa	Ascomycota	Chordata	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]; penicillin biosynthetic process [GO:0042318]	histone methyltransferase complex [GO:0035097]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; androgen receptor binding [GO:0050681]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; zinc ion binding [GO:0008270]; blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827]	penicillin biosynthetic process [GO:0042318]	blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827]		histone methyltransferase complex [GO:0035097]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]	androgen receptor binding [GO:0050681]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; zinc ion binding [GO:0008270]
d2ve6a1_d4idla___1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2ve6a2_d1u3hd2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2ve6b__d4dk3b1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	mitochondrion [GO:0005739]; alpha-catenin binding [GO:0045294]; nucleic acid binding [GO:0003676]; mitochondrial RNA modification [GO:1900864]; RNA nucleotide deletion [GO:0070706]; RNA nucleotide insertion [GO:0070705]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	mitochondrial RNA modification [GO:1900864]; RNA nucleotide deletion [GO:0070706]; RNA nucleotide insertion [GO:0070705]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	alpha-catenin binding [GO:0045294]; nucleic acid binding [GO:0003676]
d2ve6g1_d4x6bb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ve6g2_d1fned2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2vehb1_d5fsla___1		Metazoa		Chordata		acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTP diphosphatase activity [GO:0036219]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]; aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTPase activity [GO:0003924]; GTP diphosphatase activity [GO:0036219]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]
d2veic__d1hg3g___1				Euryarchaeota	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytoplasm [GO:0005737]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2vemb__d1tpvb___1		Metazoa		Chordata	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytosol [GO:0005829]	triose-phosphate isomerase activity [GO:0004807]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]
d2vexa__d5cjkb___1	Metazoa		Chordata		cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]		actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]		cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]		cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	
d2veza__d5ug4b___1	Fungi		Ascomycota	Proteobacteria	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]; polyamine catabolic process [GO:0006598]	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	polyamine catabolic process [GO:0006598]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]	cytoplasm [GO:0005737]	glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]	diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]
d2vf0a__d1tsla___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d2vf0b__d1f28b___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytosol [GO:0005829]		magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d2vf2a__d3hacb2__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; plasma membrane [GO:0005886]; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]; aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2vf4x__d2cxsa___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytosol [GO:0005829]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d2vfdb__d4y8fa1__1			Apicomplexa	Firmicutes	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2vffa__d1tmhb___1			Apicomplexa	Proteobacteria	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]
d2vffb__d1r2rb___1		Metazoa	Apicomplexa	Chordata	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]		cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]
d2vfgb__d5csrc1__1			Apicomplexa	Euryarchaeota	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2vfha__d1dkwa___1			Apicomplexa		identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]; glycosome [GO:0020015]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2vfhb__d1vgac___1			Apicomplexa	Apicomplexa	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]			identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]
d2vfna__d1o8ma___1				Proteobacteria	virus tail, fiber [GO:0098024]; endo-1,3-alpha-L-rhamnosidase activity [GO:0052775]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption by virus of host envelope lipopolysaccharide during virus entry [GO:0098995]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption by virus of host envelope lipopolysaccharide during virus entry [GO:0098995]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]; virion attachment to host cell [GO:0019062]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	virus tail, fiber [GO:0098024]	extracellular region [GO:0005576]	endo-1,3-alpha-L-rhamnosidase activity [GO:0052775]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]
d2vfqa__d1o8ea___1				Proteobacteria	virus tail, fiber [GO:0098024]; endo-1,3-alpha-L-rhamnosidase activity [GO:0052775]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption by virus of host envelope lipopolysaccharide during virus entry [GO:0098995]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]; pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption by virus of host envelope lipopolysaccharide during virus entry [GO:0098995]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]; virion attachment to host cell [GO:0019062]	pathogenesis [GO:0009405]; pectin catabolic process [GO:0045490]	virus tail, fiber [GO:0098024]	extracellular region [GO:0005576]	endo-1,3-alpha-L-rhamnosidase activity [GO:0052775]	metal ion binding [GO:0046872]; pectate lyase activity [GO:0030570]
d2vfsa1_d3nrzk1__1		Metazoa	Actinobacteria	Chordata	membrane [GO:0016020]; D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]	membrane [GO:0016020]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d2vfva1_d1ffvf2__1			Actinobacteria	Proteobacteria	membrane [GO:0016020]; D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]			membrane [GO:0016020]		D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2vfva2_d5mxua2__1		Fungi	Actinobacteria	Ascomycota	membrane [GO:0016020]; D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]		methanol metabolic process [GO:0015945]	membrane [GO:0016020]	peroxisome [GO:0005777]	D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d2vfza__d2y7ad___1	Metazoa	Metazoa	Chordata	Chordata	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]	antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]
d2vfzb__d1iina___1	Metazoa		Chordata	Proteobacteria	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]		metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]
d2vgfd3_d2vggb3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d2vgga3_d1f3xf3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d2vggd3_d1a49e3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]	ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]	positive regulation of sprouting angiogenesis [GO:1903672]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d2vglb__d4uqia___1	Metazoa	Metazoa	Chordata	Chordata	AP-2 adaptor complex [GO:0030122]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; terminal bouton [GO:0043195]; disordered domain specific binding [GO:0097718]; lipid binding [GO:0008289]; low-density lipoprotein particle receptor binding [GO:0050750]; signal sequence binding [GO:0005048]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; protein-containing complex assembly [GO:0065003]; synaptic vesicle endocytosis [GO:0048488]	AP-2 adaptor complex [GO:0030122]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; terminal bouton [GO:0043195]; disordered domain specific binding [GO:0097718]; lipid binding [GO:0008289]; low-density lipoprotein particle receptor binding [GO:0050750]; signal sequence binding [GO:0005048]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; protein-containing complex assembly [GO:0065003]; synaptic vesicle endocytosis [GO:0048488]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; protein-containing complex assembly [GO:0065003]; synaptic vesicle endocytosis [GO:0048488]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; protein-containing complex assembly [GO:0065003]; synaptic vesicle endocytosis [GO:0048488]	AP-2 adaptor complex [GO:0030122]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; terminal bouton [GO:0043195]	AP-2 adaptor complex [GO:0030122]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; terminal bouton [GO:0043195]	disordered domain specific binding [GO:0097718]; lipid binding [GO:0008289]; low-density lipoprotein particle receptor binding [GO:0050750]; signal sequence binding [GO:0005048]	disordered domain specific binding [GO:0097718]; lipid binding [GO:0008289]; low-density lipoprotein particle receptor binding [GO:0050750]; signal sequence binding [GO:0005048]
d2vglm1_d1h8ma___1	Metazoa	Fungi	Chordata	Ascomycota	AP-2 adaptor complex [GO:0030122]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; terminal bouton [GO:0043195]; disordered domain specific binding [GO:0097718]; lipid binding [GO:0008289]; low-density lipoprotein particle receptor binding [GO:0050750]; signal sequence binding [GO:0005048]; clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; protein-containing complex assembly [GO:0065003]; synaptic vesicle endocytosis [GO:0048488]	cytosol [GO:0005829]; endosome [GO:0005768]; fungal-type vacuole [GO:0000324]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; SNARE complex [GO:0031201]; palmitoyltransferase activity [GO:0016409]; SNAP receptor activity [GO:0005484]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; vacuole fusion, non-autophagic [GO:0042144]; vesicle fusion [GO:0006906]	clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; protein-containing complex assembly [GO:0065003]; synaptic vesicle endocytosis [GO:0048488]	endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; vacuole fusion, non-autophagic [GO:0042144]; vesicle fusion [GO:0006906]	AP-2 adaptor complex [GO:0030122]; glutamatergic synapse [GO:0098978]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; terminal bouton [GO:0043195]	cytosol [GO:0005829]; endosome [GO:0005768]; fungal-type vacuole [GO:0000324]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; SNARE complex [GO:0031201]	disordered domain specific binding [GO:0097718]; lipid binding [GO:0008289]; low-density lipoprotein particle receptor binding [GO:0050750]; signal sequence binding [GO:0005048]	palmitoyltransferase activity [GO:0016409]; SNAP receptor activity [GO:0005484]
d2vgwa__d2ez2a___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	tyrosine metabolic process [GO:0006570]	cytoplasm [GO:0005737]		glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	tyrosine phenol-lyase activity [GO:0050371]
d2vgwa__d2gsaa___1			Firmicutes	Cyanobacteria	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d2vh0a__d3plba___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2vh5h__d5ujtg2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	
d2vh5l__d5vk6a1__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	voltage-gated potassium channel complex [GO:0008076]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d2vh7a__d2iyib___1	Metazoa		Chordata	Proteobacteria	acylphosphatase activity [GO:0003998]; phosphate-containing compound metabolic process [GO:0006796]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]	phosphate-containing compound metabolic process [GO:0006796]				acylphosphatase activity [GO:0003998]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]
d2vh7a__d2w4dd___1	Metazoa		Chordata	Euryarchaeota	acylphosphatase activity [GO:0003998]; phosphate-containing compound metabolic process [GO:0006796]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	phosphate-containing compound metabolic process [GO:0006796]				acylphosphatase activity [GO:0003998]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]
d2vh9a__d1ms1b1__1	Viridiplantae		Streptophyta		apoplast [GO:0048046]; cell wall [GO:0005618]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]; cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]	pathogenesis [GO:0009405]	apoplast [GO:0048046]; cell wall [GO:0005618]		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]	exo-alpha-sialidase activity [GO:0004308]
d2vh9a__d1ww5c___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	apoplast [GO:0048046]; cell wall [GO:0005618]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]; cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; xyloglucan metabolic process [GO:0010411]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	apoplast [GO:0048046]; cell wall [GO:0005618]		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xyloglucan:xyloglucosyl transferase activity [GO:0016762]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d2vhda2_d4aala1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]		cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2vhdb1_d3vrda2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]			periplasmic space [GO:0042597]		cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]
d2vhdb2_d1hj5a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d2vhla2_d2p50a2__1			Firmicutes	Proteobacteria	iron ion binding [GO:0005506]; N-acetylgalactosamine-6-phosphate deacetylase activity [GO:0047419]; N-acetylglucosamine-6-phosphate deacetylase activity [GO:0008448]; protein homodimerization activity [GO:0042803]; carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]	N-acetylgalactosamine-6-phosphate deacetylase activity [GO:0047419]; N-acetylglucosamine-6-phosphate deacetylase activity [GO:0008448]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; protein homotetramerization [GO:0051289]			iron ion binding [GO:0005506]; N-acetylgalactosamine-6-phosphate deacetylase activity [GO:0047419]; N-acetylglucosamine-6-phosphate deacetylase activity [GO:0008448]; protein homodimerization activity [GO:0042803]	N-acetylgalactosamine-6-phosphate deacetylase activity [GO:0047419]; N-acetylglucosamine-6-phosphate deacetylase activity [GO:0008448]; zinc ion binding [GO:0008270]
d2vhla2_d2q6ec___1			Firmicutes	Firmicutes	iron ion binding [GO:0005506]; N-acetylgalactosamine-6-phosphate deacetylase activity [GO:0047419]; N-acetylglucosamine-6-phosphate deacetylase activity [GO:0008448]; protein homodimerization activity [GO:0042803]; carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]	metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]				iron ion binding [GO:0005506]; N-acetylgalactosamine-6-phosphate deacetylase activity [GO:0047419]; N-acetylglucosamine-6-phosphate deacetylase activity [GO:0008448]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]
d2vhmf1_d2zjpd1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2vhmo1_d1q7yo___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2vhmv1_d1xbpt1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d2vhmv1_d5bnzb2__1				Proteobacteria		cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]		glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]		cytosol [GO:0005829]		ATP binding [GO:0005524]; glutamine-tRNA ligase activity [GO:0004819]
d2vhnh1_d2hgjk1__1												
d2vhns1_d3cc4r1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2vhnz1_d2qamz1__1												
d2vhoe1_d3m85h1__1				Euryarchaeota		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]		RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]		RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2vhol1_d1a63a2__1				Proteobacteria		cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]		DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; membrane [GO:0016020]		ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]
d2vhol1_d1efwb1__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]		aspartyl-tRNA aminoacylation [GO:0006422]		cytoplasm [GO:0005737]		aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]
d2vhpc2_d2b9mc2__1												
d2vhpi1_d1hnwi___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2vi4a__d4diya___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]			cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]		
d2viaa__d4a6ta___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]		cytoplasm [GO:0005737]		glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]
d2viba__d2vmyb___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]
d2viga2_d2ddha2__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]; butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; palmitoyl-CoA oxidase activity [GO:0016401]; protein homodimerization activity [GO:0042803]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693]; very long-chain fatty acid metabolic process [GO:0000038]	butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693]; very long-chain fatty acid metabolic process [GO:0000038]	centrosome [GO:0005813]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; palmitoyl-CoA oxidase activity [GO:0016401]; protein homodimerization activity [GO:0042803]
d2vigc2_d2wbib2__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]; butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; peroxisome [GO:0005777]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; long-chain-acyl-CoA dehydrogenase activity [GO:0004466]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; very-long-chain-acyl-CoA dehydrogenase activity [GO:0017099]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	centrosome [GO:0005813]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; peroxisome [GO:0005777]	acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; long-chain-acyl-CoA dehydrogenase activity [GO:0004466]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; very-long-chain-acyl-CoA dehydrogenase activity [GO:0017099]
d2vige2_d2rehc1__1	Metazoa	Fungi	Chordata	Ascomycota	centrosome [GO:0005813]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]; butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	centrosome [GO:0005813]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d2vige2_d3mkhb2__1	Metazoa	Fungi	Chordata	Ascomycota	centrosome [GO:0005813]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]; butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	flavin adenine dinucleotide binding [GO:0050660]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]		centrosome [GO:0005813]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]	flavin adenine dinucleotide binding [GO:0050660]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d2vigf2_d2dvlb2__1	Metazoa		Chordata	Deinococcus-Thermus	centrosome [GO:0005813]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]; butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]		centrosome [GO:0005813]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d2vigh2_d1ivha1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]; butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; isovaleryl-CoA dehydrogenase activity [GO:0008470]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552]	butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552]	centrosome [GO:0005813]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]	acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]	flavin adenine dinucleotide binding [GO:0050660]; isovaleryl-CoA dehydrogenase activity [GO:0008470]
d2vika__d3ffkd2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d2vika__d3fg6b1__1	Metazoa	Metazoa	Chordata	Chordata	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]
d2vioa__d4nwla1__1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2viqa__d2bdil___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2viqa__d2g81e___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	digestion [GO:0007586]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2virb1_d1ed3b___1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	host cell surface receptor binding [GO:0046789]	
d2virb2_d2yd2a1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	host cell surface receptor binding [GO:0046789]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]
d2visa2_d2hlfd1__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d2visb1_d3fo2l2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d2vitb2_d1nunb2__1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	host cell surface receptor binding [GO:0046789]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2vitc__d5e2zc1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2vj1a__d1ca0.1__1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	digestion [GO:0007586]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2vj1b__d3zz4a1__1					cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2vj8a3_d2ejqa1__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	metal ion binding [GO:0046872]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]		aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d2vjbb__d1r9na2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	acetylcholinesterase activity [GO:0003990]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2vjga__d1tw0b2__1		Viridiplantae		Streptophyta		abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]				abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2vjga__d2yfjk2__1				Proteobacteria		biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]
d2vjgc__d4a88a___1		Viridiplantae		Streptophyta		cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]		abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2vjhc__d1v9qa___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2vjma__d4ed9a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; formyl-CoA transferase activity [GO:0033608]; oxalate catabolic process [GO:0033611]	CoA-transferase activity [GO:0008410]	oxalate catabolic process [GO:0033611]		cytoplasm [GO:0005737]		formyl-CoA transferase activity [GO:0033608]	CoA-transferase activity [GO:0008410]
d2vjnb__d1vgqb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; formyl-CoA transferase activity [GO:0033608]; oxalate catabolic process [GO:0033611]	cytoplasm [GO:0005737]; formyl-CoA transferase activity [GO:0033608]; oxalate catabolic process [GO:0033611]	oxalate catabolic process [GO:0033611]	oxalate catabolic process [GO:0033611]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	formyl-CoA transferase activity [GO:0033608]	formyl-CoA transferase activity [GO:0033608]
d2vjta__d5e29b___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2vjua1_d2vhgb1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; transposase activity [GO:0004803]; transposition, DNA-mediated [GO:0006313]	DNA binding [GO:0003677]; transposase activity [GO:0004803]; transposition, DNA-mediated [GO:0006313]	transposition, DNA-mediated [GO:0006313]	transposition, DNA-mediated [GO:0006313]			DNA binding [GO:0003677]; transposase activity [GO:0004803]	DNA binding [GO:0003677]; transposase activity [GO:0004803]
d2vjxa4_d1l7qa1__1			Bacteroidetes	Actinobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	cocaine catabolic process [GO:0050784]		cytoplasm [GO:0005737]	beta-mannosidase activity [GO:0004567]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]
d2vjxa4_d4omdf2__1		Metazoa	Bacteroidetes	Chordata	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	beta-mannosidase activity [GO:0004567]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d2vjxb5_d1vfub3__1			Bacteroidetes	Firmicutes	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]			beta-mannosidase activity [GO:0004567]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2vjyb2_d2vk8b2__1	Fungi	Fungi	Ascomycota	Ascomycota	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2vjyb3_d4c7xa2__1	Fungi		Ascomycota	Firmicutes	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]				magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d2vjyc1_d1ovmc2__1	Fungi		Ascomycota	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; auxin biosynthetic process [GO:0009851]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	auxin biosynthetic process [GO:0009851]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2vjyc1_d4jubb3__1	Fungi		Ascomycota	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2vjyd3_d2pdaa2__1	Fungi		Ascomycota	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	electron transport chain [GO:0022900]		cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d2vk1a1_d4jufd3__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2vk1a3_d2ozld1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d2vk1b2_d1upba1__1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]
d2vk1b3_d2g25a2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytosol [GO:0005829]; membrane [GO:0016020]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]
d2vk1d2_d1xltf2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	NAD binding [GO:0051287]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]; NADPH regeneration [GO:0006740]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	NADPH regeneration [GO:0006740]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]
d2vk1d2_d2vk8c2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2vk4a2_d3glse___1	Fungi	Metazoa	Ascomycota	Chordata	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d2vk4a2_d6eo0b1__1	Fungi	Metazoa	Ascomycota	Chordata	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl binding [GO:0000035]; heterocyclic compound binding [GO:1901363]; NAD+ binding [GO:0070403]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]; peptidyl-lysine demalonylation [GO:0036047]; peptidyl-lysine desuccinylation [GO:0036049]; protein desuccinylation [GO:0036048]; regulation of ketone biosynthetic process [GO:0010566]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	peptidyl-lysine demalonylation [GO:0036047]; peptidyl-lysine desuccinylation [GO:0036049]; protein desuccinylation [GO:0036048]; regulation of ketone biosynthetic process [GO:0010566]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acyl binding [GO:0000035]; heterocyclic compound binding [GO:1901363]; NAD+ binding [GO:0070403]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d2vk4a3_d3fznc1__1	Fungi		Ascomycota	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2vk4c2_d2ezub1__1	Fungi		Ascomycota	Firmicutes	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]				magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d2vk4c3_d2uzab2__1	Fungi		Ascomycota	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	electron transport chain [GO:0022900]		cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d2vk4d3_d2wvha1__1	Fungi		Ascomycota	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; ethanol metabolic process [GO:0006067]; L-phenylalanine catabolic process [GO:0006559]; tryptophan catabolic process [GO:0006569]				magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2vk8a2_d1jsca1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2vk8b1_d1bfda3__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2vk8b2_d1pnqb1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]
d2vk8b3_d5dx6b3__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; butanediol metabolic process [GO:0034077]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	butanediol metabolic process [GO:0034077]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2vk8c2_d4jucb2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2vk8c3_d1pvdb3__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2vk8d2_d3clsd2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]
d2vk9a1_d2vfza___1		Metazoa	Firmicutes	Chordata	transferase activity, transferring glycosyl groups [GO:0016757]; pathogenesis [GO:0009405]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]		Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	transferase activity, transferring glycosyl groups [GO:0016757]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d2vkaa__d2e3ba___1	Fungi	Fungi	Basidiomycota	Basidiomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2vkda1_d5uqma___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]		host cell plasma membrane [GO:0020002]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]	cysteine-type peptidase activity [GO:0008234]; glucosyltransferase activity [GO:0046527]; toxin activity [GO:0090729]
d2vkdb__d2xw3a___1			Firmicutes		metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]				metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]	
d2vkma__d2avob___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2vkmb__d1fejc___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2vkmc__d5p1na___1	Metazoa	Fungi	Chordata	Ascomycota	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]
d2vkqa__d5alfa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; 5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; tRNA 2'-phosphotransferase activity [GO:0000215]; defense response to virus [GO:0051607]; nucleotide metabolic process [GO:0009117]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	defense response to virus [GO:0051607]; nucleotide metabolic process [GO:0009117]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; nucleotide binding [GO:0000166]; tRNA 2'-phosphotransferase activity [GO:0000215]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d2vkrd__d2fug91__1			Crenarchaeota	Deinococcus-Thermus	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; zinc ion binding [GO:0008270]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]				plasma membrane [GO:0005886]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; zinc ion binding [GO:0008270]	quinone binding [GO:0048038]
d2vkwa2_d5j7cd1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; virus receptor activity [GO:0001618]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; commissural neuron axon guidance [GO:0071679]; interferon-gamma-mediated signaling pathway [GO:0060333]; MAPK cascade [GO:0000165]; regulation of semaphorin-plexin signaling pathway [GO:2001260]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; commissural neuron axon guidance [GO:0071679]; interferon-gamma-mediated signaling pathway [GO:0060333]; MAPK cascade [GO:0000165]; regulation of semaphorin-plexin signaling pathway [GO:2001260]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; virus receptor activity [GO:0001618]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2vkwb2_d1lqss2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; virus receptor activity [GO:0001618]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; commissural neuron axon guidance [GO:0071679]; interferon-gamma-mediated signaling pathway [GO:0060333]; MAPK cascade [GO:0000165]; regulation of semaphorin-plexin signaling pathway [GO:2001260]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; interleukin-10 binding [GO:0019969]; interleukin-10 receptor activity [GO:0004920]; signaling receptor activity [GO:0038023]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of autophagy [GO:0010507]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of synapse organization [GO:0050807]; response to lipopolysaccharide [GO:0032496]; ubiquitin-dependent endocytosis [GO:0070086]	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; commissural neuron axon guidance [GO:0071679]; interferon-gamma-mediated signaling pathway [GO:0060333]; MAPK cascade [GO:0000165]; regulation of semaphorin-plexin signaling pathway [GO:2001260]	cytokine-mediated signaling pathway [GO:0019221]; negative regulation of autophagy [GO:0010507]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of synapse organization [GO:0050807]; response to lipopolysaccharide [GO:0032496]; ubiquitin-dependent endocytosis [GO:0070086]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; virus receptor activity [GO:0001618]	cytokine receptor activity [GO:0004896]; interleukin-10 binding [GO:0019969]; interleukin-10 receptor activity [GO:0004920]; signaling receptor activity [GO:0038023]
d2vkxb2_d2flbt1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; virus receptor activity [GO:0001618]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; commissural neuron axon guidance [GO:0071679]; interferon-gamma-mediated signaling pathway [GO:0060333]; MAPK cascade [GO:0000165]; regulation of semaphorin-plexin signaling pathway [GO:2001260]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; commissural neuron axon guidance [GO:0071679]; interferon-gamma-mediated signaling pathway [GO:0060333]; MAPK cascade [GO:0000165]; regulation of semaphorin-plexin signaling pathway [GO:2001260]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	identical protein binding [GO:0042802]; virus receptor activity [GO:0001618]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d2vkxc2_d5dftb___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; virus receptor activity [GO:0001618]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; commissural neuron axon guidance [GO:0071679]; interferon-gamma-mediated signaling pathway [GO:0060333]; MAPK cascade [GO:0000165]; regulation of semaphorin-plexin signaling pathway [GO:2001260]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; commissural neuron axon guidance [GO:0071679]; interferon-gamma-mediated signaling pathway [GO:0060333]; MAPK cascade [GO:0000165]; regulation of semaphorin-plexin signaling pathway [GO:2001260]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	identical protein binding [GO:0042802]; virus receptor activity [GO:0001618]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]
d2vl2c__d2obkf___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]	
d2vl4a1_d1jz1l1__1			Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]	
d2vl4a3_d3t2pd4__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vl4b3_d1hn1a1__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vl4b5_d1ji2b3__1			Bacteroidetes	Firmicutes	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]			beta-mannosidase activity [GO:0004567]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2vl5a1_d1pywb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d2vl5a1_d4lcwe2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2vl5b1_d1ibgl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2vl5b2_d1t83c2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2vl5d1_d1s9vd1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; interferon-gamma-mediated signaling pathway [GO:0060333]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; interferon-gamma-mediated signaling pathway [GO:0060333]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d2vl6a__d1bvsa3__1			Crenarchaeota	Actinobacteria	MCM complex [GO:0042555]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA replication origin binding [GO:0003688]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; DNA replication initiation [GO:0006270]	Holliday junction helicase complex [GO:0009379]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	DNA replication initiation [GO:0006270]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	MCM complex [GO:0042555]; nucleus [GO:0005634]	Holliday junction helicase complex [GO:0009379]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA replication origin binding [GO:0003688]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]
d2vl9b__d4nhzf1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	transferase activity [GO:0016740]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]	transferase activity [GO:0016740]
d2vlea__d5ac1a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	cytosol [GO:0005829]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]
d2vlec__d3rhjc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]
d2vled__d4v37c___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	chloroplast [GO:0009507]; betaine-aldehyde dehydrogenase activity [GO:0008802]; cellular aldehyde metabolic process [GO:0006081]; glycine betaine biosynthetic process from choline [GO:0019285]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cellular aldehyde metabolic process [GO:0006081]; glycine betaine biosynthetic process from choline [GO:0019285]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	chloroplast [GO:0009507]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	betaine-aldehyde dehydrogenase activity [GO:0008802]
d2vlee__d4nmjd___1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2vleg__d4go2d___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]
d2vleh__d5ekcf___1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2vlje2_d5vkkl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2vlkb2_d1otsd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2vlke2_d4pjff2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2vlke2_d5mvzb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d2vlla1_d4dk3a1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	mitochondrion [GO:0005739]; alpha-catenin binding [GO:0045294]; nucleic acid binding [GO:0003676]; mitochondrial RNA modification [GO:1900864]; RNA nucleotide deletion [GO:0070706]; RNA nucleotide insertion [GO:0070705]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	mitochondrial RNA modification [GO:1900864]; RNA nucleotide deletion [GO:0070706]; RNA nucleotide insertion [GO:0070705]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	alpha-catenin binding [GO:0045294]; nucleic acid binding [GO:0003676]
d2vllb2_d1mhph2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]
d2vlld1_d4x6cf2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2vlle2_d5hysl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2vlmd1_d3ay4a2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	IgG binding [GO:0019864]
d2vlme1_d2iffl2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2vlna__d2jbgc___1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	extrachromosomal circular DNA [GO:0005727]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	bacteriocin immunity [GO:0030153]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	protein-containing complex [GO:0032991]	extrachromosomal circular DNA [GO:0005727]	protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d2vloa2_d2wpta___1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	extrachromosomal circular DNA [GO:0005727]; protein-containing complex [GO:0032991]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; pathogenesis [GO:0009405]	bacteriocin immunity [GO:0030153]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; pathogenesis [GO:0009405]	protein-containing complex [GO:0032991]	extrachromosomal circular DNA [GO:0005727]; protein-containing complex [GO:0032991]	protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]
d2vlpa__d3gjnd___1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	extrachromosomal circular DNA [GO:0005727]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	bacteriocin immunity [GO:0030153]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	protein-containing complex [GO:0032991]	extrachromosomal circular DNA [GO:0005727]	protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d2vlqb__d4uhpg___1			Proteobacteria	Proteobacteria	protein-containing complex [GO:0032991]; protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	protein-containing complex [GO:0032991]		protein domain specific binding [GO:0019904]; toxic substance binding [GO:0015643]	toxic substance binding [GO:0015643]
d2vlrb2_d2hffa1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2vlre2_d4kphm1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2vlrf1_d2fath2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2vlrf2_d1n5ag2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2vlrj1_d3fo9a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2vlrj2_d5mera2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2vlsa__d2qfoa___1		Metazoa		Chordata		axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]		axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d2vlta__d4k7na___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	protein disulfide oxidoreductase activity [GO:0015035]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]
d2vltb__d4i2ta1__1	Viridiplantae	Viridiplantae	Streptophyta	Chlorophyta	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	protein disulfide oxidoreductase activity [GO:0015035]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d2vlua__d2ntoa1__1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]	cytoplasm [GO:0005737]	protein disulfide oxidoreductase activity [GO:0015035]	glutathione transferase activity [GO:0004364]
d2vlva__d1gsea2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	protein disulfide oxidoreductase activity [GO:0015035]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2vlxa__d3bj3b___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2vlxa__d4h0mw___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2vm1d__d1de2a___1	Viridiplantae		Streptophyta		cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cell [GO:0005623]		protein disulfide oxidoreductase activity [GO:0015035]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d2vm3a1_d1as7a1__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2vm3a2_d1aozb3__1		Viridiplantae	Proteobacteria	Streptophyta	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	nitrogen compound metabolic process [GO:0006807]			extracellular region [GO:0005576]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]
d2vm3a2_d2fjsb2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2vm4a1_d5i6ma1__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2vmfa3_d1jyzl2__1			Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]	
d2vmfa3_d3dyob2__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vmfa5_d1btca___1		Viridiplantae	Bacteroidetes	Streptophyta	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	polysaccharide catabolic process [GO:0000272]			beta-mannosidase activity [GO:0004567]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d2vmfb4_d1jyyb3__1			Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]	
d2vmfb5_d1jg9a2__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	beta-mannosidase activity [GO:0004567]	amylosucrase activity [GO:0047669]
d2vmfb5_d3rikc2__1		Metazoa	Bacteroidetes	Chordata	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	beta-mannosidase activity [GO:0004567]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d2vmga1_d3mv141__1			Firmicutes	Proteobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vmha__d2vngb___1			Firmicutes	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2vmja2_d2ppac2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2vmla__d1xy0d___1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2vmlc__d2uult___1			Cyanobacteria		phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]			
d2vmqa__d4r5za1__1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	histidine biosynthetic process [GO:0000105]	cytoplasm [GO:0005737]		glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]
d2vmra__d3tata___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aromatic-amino-acid:2-oxoglutarate aminotransferase activity [GO:0008793]; identical protein binding [GO:0042802]; L-leucine:2-oxoglutarate aminotransferase activity [GO:0050048]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; aspartate biosynthetic process [GO:0006532]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]; leucine biosynthetic process [GO:0009098]; tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate [GO:0019292]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	aspartate biosynthetic process [GO:0006532]; leucine biosynthetic process [GO:0009098]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]; tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate [GO:0019292]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	aromatic-amino-acid:2-oxoglutarate aminotransferase activity [GO:0008793]; identical protein binding [GO:0042802]; L-leucine:2-oxoglutarate aminotransferase activity [GO:0050048]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d2vmta__d4wyeb___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	biotin biosynthetic process [GO:0009102]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]
d2vmva__d3ei9a1__1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d2vmxa__d1qj5b___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	biotin biosynthetic process [GO:0009102]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]
d2vmya__d2hoxa___1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	vacuole [GO:0005773]; alliin lyase activity [GO:0047654]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]		cytoplasm [GO:0005737]	vacuole [GO:0005773]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	alliin lyase activity [GO:0047654]
d2vn0a__d4uhld1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]; cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]
d2vn3a1_d1aozb1__1		Viridiplantae	Proteobacteria	Streptophyta	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	nitrogen compound metabolic process [GO:0006807]			extracellular region [GO:0005576]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]
d2vn3a1_d5x1fb2__1		Metazoa	Proteobacteria	Chordata	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	nitrogen compound metabolic process [GO:0006807]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2vn3a2_d2y69b2__1		Metazoa	Proteobacteria	Chordata	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	nitrogen compound metabolic process [GO:0006807]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2vn5a__d5gy1a2__1			Firmicutes	Firmicutes	cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			cellulose binding [GO:0030248]; metal ion binding [GO:0046872]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2vn6a__d4dh2c1__1			Firmicutes	Firmicutes	cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			cellulose binding [GO:0030248]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d2vnga1_d4duxb1__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vnha2_d3qfsa2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d2vnha2_d3w2fa2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]		cholesterol biosynthetic process [GO:0006695]	cytoplasm [GO:0005737]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d2vnia2_d1gr1a2__1			Proteobacteria	Cyanobacteria	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d2vnja2_d1krha2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]; toluene catabolic process [GO:0042203]		toluene catabolic process [GO:0042203]	cytoplasm [GO:0005737]		ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]
d2vnja2_d5vw5a2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]			cytoplasm [GO:0005737]	chloroplast [GO:0009507]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d2vnka2_d1qfyb2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]	cytoplasm [GO:0005737]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	ferredoxin-NADP+ reductase activity [GO:0004324]
d2vnka2_d4yaua3__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]		carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d2vnkb1_d1quea1__1			Proteobacteria	Cyanobacteria	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d2vnkb2_d3fpkb2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]			cytoplasm [GO:0005737]	cytosol [GO:0005829]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d2vnkc2_d5gv8a2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]		cholesterol biosynthetic process [GO:0006695]	cytoplasm [GO:0005737]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d2vnpb2_d5ghna___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTP diphosphatase activity [GO:0036219]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]; aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTPase activity [GO:0003924]; GTP diphosphatase activity [GO:0036219]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]
d2vnqb2_d3q93b___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTP diphosphatase activity [GO:0036219]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]; aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTPase activity [GO:0003924]; GTP diphosphatase activity [GO:0036219]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]
d2vo2x__d1cpda___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	chloroplast [GO:0009507]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2vo4b1_d4v2nb___1	Viridiplantae	Metazoa	Streptophyta	Arthropoda	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]	glutathione transferase activity [GO:0004364]	protein disulfide oxidoreductase activity [GO:0015035]
d2vo4b2_d2j9ha2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2vo5a1_d1jz4c2__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vo5a3_d2vota2__1			Bacteroidetes	Bacteroidetes	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]			beta-mannosidase activity [GO:0004567]	beta-mannosidase activity [GO:0004567]
d2vo5a4_d3jxsb___1			Bacteroidetes	Bacteroidetes	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	xylan catabolic process [GO:0045493]			beta-mannosidase activity [GO:0004567]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2vo5a4_d4arxc3__1			Bacteroidetes	Firmicutes	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	sporulation resulting in formation of a cellular spore [GO:0030435]			beta-mannosidase activity [GO:0004567]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d2vo5a5_d1vfka5__1			Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]	
d2vo5b1_d1jz0d2__1			Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]	
d2vo5b4_d1jywa3__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vo8a1_d1xbda___1			Firmicutes	Actinobacteria	carbohydrate binding [GO:0030246]; exo-alpha-sialidase activity [GO:0004308]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]			carbohydrate binding [GO:0030246]; exo-alpha-sialidase activity [GO:0004308]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; polysaccharide binding [GO:0030247]
d2vodb2_d2km8c2__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nuclear chromosome, telomeric region [GO:0000784]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049]; histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	mRNA polyadenylation [GO:0006378]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	cytoplasm [GO:0005737]; nuclear chromosome, telomeric region [GO:0000784]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d2vokb1_d5jdba___1	Metazoa		Chordata		autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; cell cycle [GO:0007049]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein deubiquitination [GO:0090086]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of autophagy [GO:0010508]; positive regulation of cell cycle [GO:0045787]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein trimerization [GO:0070206]; protein ubiquitination [GO:0016567]; response to interferon-gamma [GO:0034341]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	cell cycle [GO:0007049]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein deubiquitination [GO:0090086]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of autophagy [GO:0010508]; positive regulation of cell cycle [GO:0045787]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein trimerization [GO:0070206]; protein ubiquitination [GO:0016567]; response to interferon-gamma [GO:0034341]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	
d2vola1_d2j8oa1__1		Metazoa		Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d2volb1_d2dvbb___1		Viridiplantae		Streptophyta		carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]						carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2voma__d2yc8l___1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]		methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	
d2vomc__d1ssdb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]
d2vomc__d4obta1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	apoplast [GO:0048046]; cell wall [GO:0005618]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuolar membrane [GO:0005774]; vacuole [GO:0005773]; copper ion binding [GO:0005507]; triose-phosphate isomerase activity [GO:0004807]; cellular carbohydrate metabolic process [GO:0044262]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; response to cadmium ion [GO:0046686]; response to zinc ion [GO:0010043]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cellular carbohydrate metabolic process [GO:0044262]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; response to cadmium ion [GO:0046686]; response to zinc ion [GO:0010043]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	apoplast [GO:0048046]; cell wall [GO:0005618]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuolar membrane [GO:0005774]; vacuole [GO:0005773]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	copper ion binding [GO:0005507]; triose-phosphate isomerase activity [GO:0004807]
d2vona2_d2lxua1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear chromosome, telomeric region [GO:0000784]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049]; histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; nuclear chromosome, telomeric region [GO:0000784]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049]	poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]
d2vooa2_d2mqoa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear chromosome, telomeric region [GO:0000784]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049]; histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; ribonucleoprotein complex [GO:1990904]; ribonucleoprotein granule [GO:0035770]; mRNA 3'-UTR binding [GO:0003730]; mRNA CDS binding [GO:1990715]; pre-mRNA intronic binding [GO:0097157]; transcription regulatory region DNA binding [GO:0044212]; cellular response to amino acid starvation [GO:0034198]; circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to peptide [GO:1901652]	histone mRNA metabolic process [GO:0008334]; IRES-dependent viral translational initiation [GO:0075522]; nuclear histone mRNA catabolic process [GO:0071045]; protein localization to cytoplasmic stress granule [GO:1903608]; tRNA 3'-end processing [GO:0042780]; tRNA 5'-leader removal [GO:0001682]; tRNA export from nucleus [GO:0006409]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	cellular response to amino acid starvation [GO:0034198]; circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to peptide [GO:1901652]	cytoplasm [GO:0005737]; nuclear chromosome, telomeric region [GO:0000784]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; ribonucleoprotein complex [GO:1990904]; ribonucleoprotein granule [GO:0035770]	mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; sequence-specific mRNA binding [GO:1990825]; tRNA binding [GO:0000049]	mRNA 3'-UTR binding [GO:0003730]; mRNA CDS binding [GO:1990715]; pre-mRNA intronic binding [GO:0097157]; transcription regulatory region DNA binding [GO:0044212]
d2vota1_d1jyva1__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vota5_d3t0ac3__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2votb1_d3iapb2__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2votb1_d4duwb4__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2votb3_d3czjd4__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2votb5_d5g1ma1__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	cytoplasm [GO:0005737]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]	beta-mannosidase activity [GO:0004567]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]
d2voub2_d2ignd2__1		Fungi	Actinobacteria	Basidiomycota	2,6-dihydroxypyridine 3-monooxygenase activity [GO:0018663]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; protein homodimerization activity [GO:0042803]; nicotine catabolic process [GO:0019608]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	nicotine catabolic process [GO:0019608]				2,6-dihydroxypyridine 3-monooxygenase activity [GO:0018663]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; protein homodimerization activity [GO:0042803]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]
d2vp0a__d4p32b___1	Metazoa		Arthropoda	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; lipopolysaccharide floppase activity [GO:0015437]; protein-containing complex binding [GO:0044877]; lipopolysaccharide transport [GO:0015920]; transmembrane transport [GO:0055085]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	lipopolysaccharide transport [GO:0015920]; transmembrane transport [GO:0055085]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; lipopolysaccharide floppase activity [GO:0015437]; protein-containing complex binding [GO:0044877]
d2vp1a__d3rtfb___1		Metazoa	Cyanobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; thylakoid membrane [GO:0042651]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; thylakoid membrane [GO:0042651]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2vp1b__d5lhua1__1			Cyanobacteria	Actinobacteria	outer membrane-bounded periplasmic space [GO:0030288]; thylakoid membrane [GO:0042651]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	histidine biosynthetic process [GO:0000105]	outer membrane-bounded periplasmic space [GO:0030288]; thylakoid membrane [GO:0042651]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	AMP binding [GO:0016208]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d2vp2b__d2ff7a2__1	Metazoa		Arthropoda	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type I protein secretion system complex [GO:0030256]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; peptidase activity [GO:0008233]; toxin transmembrane transporter activity [GO:0019534]; protein secretion by the type I secretion system [GO:0030253]; secretion by cell [GO:0032940]; toxin transport [GO:1901998]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	protein secretion by the type I secretion system [GO:0030253]; secretion by cell [GO:0032940]; toxin transport [GO:1901998]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type I protein secretion system complex [GO:0030256]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]	ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; peptidase activity [GO:0008233]; toxin transmembrane transporter activity [GO:0019534]
d2vp4a__d2zs9a___1	Metazoa		Arthropoda	Actinobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d2vp9a__d3qvvb___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	cytosol [GO:0005829]; aryl sulfotransferase activity [GO:0004062]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]	aryl sulfotransferase activity [GO:0004062]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]
d2vpnb__d3mbpa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	transmembrane transport [GO:0055085]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d2vpqa1_d3vpda1__1			Firmicutes	Deinococcus-Thermus	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]			acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]
d2vpqa3_d2ys6a3__1			Firmicutes	Firmicutes	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]			acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d2vpqb2_d5c1pc2__1			Firmicutes	Proteobacteria	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]		cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2vpqb3_d2v58b3__1			Firmicutes	Proteobacteria	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2vq0b1_d1r08.1__1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2vq1a1_d4q9ca___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2vq1a2_d4lsrl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	structural molecule activity [GO:0005198]
d2vqda1_d5j2uf1__1		Metazoa	Proteobacteria	Chordata	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]		cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d2vqda3_d2v59a3__1			Proteobacteria	Proteobacteria	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2vqda3_d4mv6a3__1			Proteobacteria	Proteobacteria	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]			acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2vqef1_d1cqma___1			Deinococcus-Thermus	Deinococcus-Thermus	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2vqeq1_d2vw9a___1			Deinococcus-Thermus	Proteobacteria	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	single-stranded DNA binding [GO:0003697]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]	translation [GO:0006412]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]	ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	single-stranded DNA binding [GO:0003697]
d2vqfb1_d1vs5b1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d2vqfh1_d2gy9h1__1			Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	
d2vqfq1_d1ltlc___1			Deinococcus-Thermus	Euryarchaeota	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	MCM complex [GO:0042555]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; metal ion binding [GO:0046872]; DNA replication initiation [GO:0006270]	translation [GO:0006412]	DNA replication initiation [GO:0006270]	ribosome [GO:0005840]	MCM complex [GO:0042555]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; metal ion binding [GO:0046872]
d2vqta2_d2vzsa1__1			Bacteroidetes	Actinobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]	beta-mannosidase activity [GO:0004567]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2vqta5_d4puda___1			Bacteroidetes	Firmicutes	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	beta-mannosidase activity [GO:0004567]	endo-1,4-beta-xylanase activity [GO:0031176]
d2vqtb1_d3t2pa2__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vqtb2_d3dyoc2__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vqtb5_d2pwfb1__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]			beta-mannosidase activity [GO:0004567]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d2vqua3_d3t2od2__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vqua5_d1jz2b5__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vqub4_d3ziwe2__1			Bacteroidetes	Firmicutes	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]			extracellular region [GO:0005576]	beta-mannosidase activity [GO:0004567]	toxin activity [GO:0090729]
d2vqub5_d1ukta4__1			Bacteroidetes	Firmicutes	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	beta-mannosidase activity [GO:0004567]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2vr0d__d4fasb___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; denitrification pathway [GO:0019333]; oxidation-reduction process [GO:0055114]		denitrification pathway [GO:0019333]; oxidation-reduction process [GO:0055114]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d2vr1a2_d5dmxc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2vr4a1_d3t0ab2__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vr4b1_d3hn3d2__1		Metazoa	Bacteroidetes	Chordata	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	beta-mannosidase activity [GO:0004567]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]
d2vr6f__d4b3ec___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d2vr7a__d1f1aa___1	Metazoa	Fungi	Chordata	Ascomycota	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]
d2vrea1_d5ducc1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; delta3,5-delta2,4-dienoyl-CoA isomerase activity [GO:0051750]; fatty acid beta-oxidation [GO:0006635]; protein targeting to peroxisome [GO:0006625]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	fatty acid beta-oxidation [GO:0006635]; protein targeting to peroxisome [GO:0006625]	fatty acid beta-oxidation [GO:0006635]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	delta3,5-delta2,4-dienoyl-CoA isomerase activity [GO:0051750]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]
d2vrfa1_d2r4hc1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; dystrophin-associated glycoprotein complex [GO:0016010]; focal adhesion [GO:0005925]; membrane [GO:0016020]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alpha-actinin binding [GO:0051393]; ATP binding [GO:0005524]; molecular adaptor activity [GO:0060090]; protein C-terminus binding [GO:0008022]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; positive regulation of cell-cell adhesion [GO:0022409]; protein-containing complex assembly [GO:0065003]; signal transduction [GO:0007165]		cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; positive regulation of cell-cell adhesion [GO:0022409]; protein-containing complex assembly [GO:0065003]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; dystrophin-associated glycoprotein complex [GO:0016010]; focal adhesion [GO:0005925]; membrane [GO:0016020]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	actin binding [GO:0003779]; calmodulin binding [GO:0005516]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	alpha-actinin binding [GO:0051393]; ATP binding [GO:0005524]; molecular adaptor activity [GO:0060090]; protein C-terminus binding [GO:0008022]
d2vrlb2_d3qsea2__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	tetrahydrofolate metabolic process [GO:0046653]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	sarcosine oxidase activity [GO:0008115]
d2vrma2_d2voua2__1	Metazoa		Chordata	Actinobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	2,6-dihydroxypyridine 3-monooxygenase activity [GO:0018663]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; protein homodimerization activity [GO:0042803]; nicotine catabolic process [GO:0019608]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	nicotine catabolic process [GO:0019608]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	2,6-dihydroxypyridine 3-monooxygenase activity [GO:0018663]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; protein homodimerization activity [GO:0042803]
d2vrmb2_d1daog2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d2vrpa__d3bc7a___1	Metazoa		Chordata		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]		regulation of cytokine activity [GO:0060300]		extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d2vrrb__d5azha___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; defense response to Gram-positive bacterium [GO:0050830]; macroautophagy [GO:0016236]; positive regulation of autophagosome maturation [GO:1901098]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; defense response to Gram-positive bacterium [GO:0050830]; macroautophagy [GO:0016236]; positive regulation of autophagosome maturation [GO:1901098]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d2vs4a__d1h7ha___1	Metazoa		Chordata	Proteobacteria	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	cytoplasm [GO:0005737]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]
d2vs4b__d1tw5a___1	Metazoa	Metazoa	Chordata	Chordata	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d2vs5b__d1g8oa___1	Metazoa	Metazoa	Chordata	Chordata	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d2vs6b__d3le7a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]; regulation of defense response to virus [GO:0050688]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2vspa__d2x7za___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]; carnitine transport [GO:0015879]; cell population proliferation [GO:0008283]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of anion transport [GO:0044070]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]; cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	carnitine transport [GO:0015879]; cell population proliferation [GO:0008283]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of anion transport [GO:0044070]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]	actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]	PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]	cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]
d2vspc__d2enoa1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]; carnitine transport [GO:0015879]; cell population proliferation [GO:0008283]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of anion transport [GO:0044070]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]	basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; integral component of mitochondrial outer membrane [GO:0031307]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic density membrane [GO:0098839]; protein C-terminus binding [GO:0008022]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sprouting angiogenesis [GO:1903671]; protein targeting [GO:0006605]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of endocytosis [GO:0030100]; regulation of Notch signaling pathway [GO:0008593]; Rho protein signal transduction [GO:0007266]	carnitine transport [GO:0015879]; cell population proliferation [GO:0008283]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of anion transport [GO:0044070]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]	cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sprouting angiogenesis [GO:1903671]; protein targeting [GO:0006605]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of endocytosis [GO:0030100]; regulation of Notch signaling pathway [GO:0008593]; Rho protein signal transduction [GO:0007266]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; integral component of mitochondrial outer membrane [GO:0031307]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic density membrane [GO:0098839]	PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]	protein C-terminus binding [GO:0008022]
d2vspc__d3rl8b___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]; carnitine transport [GO:0015879]; cell population proliferation [GO:0008283]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of anion transport [GO:0044070]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]	adherens junction [GO:0005912]; beta-catenin destruction complex [GO:0030877]; bicellular tight junction [GO:0005923]; catenin complex [GO:0016342]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; Wnt signalosome [GO:1990909]; beta-catenin binding [GO:0008013]; dynein complex binding [GO:0070840]; gamma-catenin binding [GO:0045295]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin protein ligase binding [GO:0031625]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; insulin receptor signaling pathway [GO:0008286]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of microtubule depolymerization [GO:0007026]; pattern specification process [GO:0007389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration [GO:0030335]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of pseudopodium assembly [GO:0031274]; protein deubiquitination [GO:0016579]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell differentiation [GO:0045595]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055]	carnitine transport [GO:0015879]; cell population proliferation [GO:0008283]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of anion transport [GO:0044070]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]	beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; insulin receptor signaling pathway [GO:0008286]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of microtubule depolymerization [GO:0007026]; pattern specification process [GO:0007389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration [GO:0030335]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of pseudopodium assembly [GO:0031274]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homooligomerization [GO:0051260]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell differentiation [GO:0045595]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]	adherens junction [GO:0005912]; beta-catenin destruction complex [GO:0030877]; bicellular tight junction [GO:0005923]; catenin complex [GO:0016342]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; Wnt signalosome [GO:1990909]	PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]	beta-catenin binding [GO:0008013]; dynein complex binding [GO:0070840]; gamma-catenin binding [GO:0045295]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin protein ligase binding [GO:0031625]
d2vssb__d3tv5c1__1		Fungi	Proteobacteria	Ascomycota	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]		acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]		acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d2vssd__d3ktki___1			Proteobacteria	Firmicutes	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]
d2vssf__d2j5sb___1			Proteobacteria	Cyanobacteria	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	catalytic activity [GO:0003824]					trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	catalytic activity [GO:0003824]
d2vt7b__d5tnlc___1	Metazoa		Chordata	Proteobacteria	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	hydrolase activity [GO:0016787]	acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]		acetylcholinesterase activity [GO:0003990]	hydrolase activity [GO:0016787]
d2vtul1_d1h8ja___1					T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; regulation of translation [GO:0006417]		regulation of translation [GO:0006417]		T=3 icosahedral viral capsid [GO:0039617]		identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	
d2vtza1_d2vu0a2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2vtzb1_d2wl5d2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2vtzc2_d1fj8d2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2vtzd1_d4yufa2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2vu0b2_d1u0uc1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	pinosylvin synthase activity [GO:0050198]
d2vu1a2_d5cbqa2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2vu1b2_d1m3kd1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2vu1b2_d2wuab2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	acetyl-CoA C-acyltransferase activity [GO:0003988]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acyltransferase activity [GO:0003988]
d2vu1c2_d1ulqf2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2vu1c2_d4qava1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d2vu2a2_d1m1tc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2vu2c2_d4c70a2__1			Proteobacteria		cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]		poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	
d2vu5a__d4dz6d1__1			Firmicutes	Spirochaetes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2vu9a1_d5w11a___1		Fungi	Firmicutes	Ascomycota	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	negative regulation of neurotransmitter secretion [GO:0046929]	cellulose catabolic process [GO:0030245]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2vubf__d4mzph1__1			Proteobacteria	Firmicutes	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity [GO:0008657]; plasmid maintenance [GO:0006276]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; RNA binding [GO:0003723]	plasmid maintenance [GO:0006276]				DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity [GO:0008657]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; RNA binding [GO:0003723]
d2vudb__d4aoca___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2vudd__d2bv4b___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2vueb1_d4f5sb2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2vufb2_d4z69a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2vukb__d1vkxa2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2vuoa1_d1d3la2__1	Metazoa	Metazoa	Chordata	Chordata	immunoglobulin receptor binding [GO:0034987]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]		acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]		cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	immunoglobulin receptor binding [GO:0034987]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]
d2vuoa1_d2or7a1__1	Metazoa	Metazoa	Chordata	Chordata	immunoglobulin receptor binding [GO:0034987]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ferritin receptor activity [GO:0070287]; iron ion transport [GO:0006826]		iron ion transport [GO:0006826]		cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	immunoglobulin receptor binding [GO:0034987]	ferritin receptor activity [GO:0070287]
d2vuob1_d1qful1__1	Metazoa		Chordata	Negarnaviricota	immunoglobulin receptor binding [GO:0034987]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	immunoglobulin receptor binding [GO:0034987]	host cell surface receptor binding [GO:0046789]
d2vuob2_d1h8sa2__1	Metazoa		Chordata		immunoglobulin receptor binding [GO:0034987]						immunoglobulin receptor binding [GO:0034987]	
d2vuob2_d3ob0l1__1	Metazoa		Chordata		immunoglobulin receptor binding [GO:0034987]						immunoglobulin receptor binding [GO:0034987]	
d2vv6d__d2z6da___1		Viridiplantae	Proteobacteria	Streptophyta	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	cell [GO:0005623]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plastid [GO:0009536]; ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein serine/threonine kinase activity [GO:0004674]; chloroplast relocation [GO:0009902]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-chromophore linkage [GO:0018298]; response to blue light [GO:0009637]; stomatal movement [GO:0010118]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	chloroplast relocation [GO:0009902]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; protein phosphorylation [GO:0006468]; response to blue light [GO:0009637]; stomatal movement [GO:0010118]	integral component of plasma membrane [GO:0005887]	cell [GO:0005623]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plastid [GO:0009536]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein serine/threonine kinase activity [GO:0004674]
d2vv7a__d4wn5b___1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein dimerization activity [GO:0046983]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]	integral component of plasma membrane [GO:0005887]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein dimerization activity [GO:0046983]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]
d2vv8a__d1ot9a___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]		ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d2vv8d__d3ue6a___1			Proteobacteria		integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]		integral component of plasma membrane [GO:0005887]		ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d2vvax__d4xixh___1	Metazoa	Viridiplantae	Chordata	Chlorophyta	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d2vvob__d4lfkc___1			Actinobacteria		extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]		ribose-5-phosphate isomerase activity [GO:0004751]	
d2vvpa__d4lflc___1			Actinobacteria		extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]		ribose-5-phosphate isomerase activity [GO:0004751]	
d2vvpc__d4lfmc___1			Actinobacteria		extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]		ribose-5-phosphate isomerase activity [GO:0004751]	
d2vvpd__d3k7pa___1			Actinobacteria		extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		ribose-5-phosphate isomerase activity [GO:0004751]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]
d2vvqc__d2vvrd___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]; D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]	extracellular region [GO:0005576]		ribose-5-phosphate isomerase activity [GO:0004751]	allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]
d2vvra__d4lfnd___1			Proteobacteria		allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]; D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]		D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]				allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]	
d2vvrb__d2vvpb___1			Proteobacteria	Actinobacteria	allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]; D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]	allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]	ribose-5-phosphate isomerase activity [GO:0004751]
d2vvrb__d4lflc___1			Proteobacteria		allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]; D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]		D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]				allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]	
d2vvrc__d2bese___1			Proteobacteria	Actinobacteria	allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]; D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]	allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]	ribose-5-phosphate isomerase activity [GO:0004751]
d2vvrd__d3k7sc___1			Proteobacteria		allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]; D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]			allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]
d2vvsa2_d3vd5a3__1			Bacteroidetes	Proteobacteria	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vvva__d2agex___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2vw4a1_d2e86c1__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2vw4a2_d2ppeb2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2vw4a2_d4a2ea1__1		Fungi	Proteobacteria	Basidiomycota	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	nitrogen compound metabolic process [GO:0006807]				copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2vw4b1_d2eikb1__1		Metazoa	Proteobacteria	Chordata	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	nitrogen compound metabolic process [GO:0006807]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2vw4b2_d2xwzc1__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2vw4b2_d4ysca2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2vw5b__d3q5lc1__1	Fungi		Ascomycota		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]
d2vw5d__d4l8za___1	Fungi	Metazoa	Ascomycota	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d2vw6a2_d1aaja___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	nitrogen compound metabolic process [GO:0006807]			periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2vw7b2_d1j9tb1__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2vw8a1_d3dh8a1__1			Proteobacteria	Proteobacteria	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; secondary metabolite biosynthetic process [GO:0044550]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; secondary metabolite biosynthetic process [GO:0044550]	secondary metabolite biosynthetic process [GO:0044550]	secondary metabolite biosynthetic process [GO:0044550]			hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2vw9b__d2z0sa1__1			Proteobacteria	Crenarchaeota	single-stranded DNA binding [GO:0003697]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA catabolic process [GO:0006401]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]	RNA catabolic process [GO:0006401]		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	single-stranded DNA binding [GO:0003697]	poly(A) binding [GO:0008143]
d2vwla__d3keea___1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2vwsb__d3fa3l___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; 2-keto-3-deoxy-L-rhamnonate aldolase activity [GO:0106099]; aldehyde-lyase activity [GO:0016832]; magnesium ion binding [GO:0000287]; nickel cation binding [GO:0016151]; cellular aromatic compound metabolic process [GO:0006725]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	cellular aromatic compound metabolic process [GO:0006725]		cytoplasm [GO:0005737]		2-keto-3-deoxy-L-rhamnonate aldolase activity [GO:0106099]; aldehyde-lyase activity [GO:0016832]; magnesium ion binding [GO:0000287]; nickel cation binding [GO:0016151]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2vwsc__d3fa3i___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; 2-keto-3-deoxy-L-rhamnonate aldolase activity [GO:0106099]; aldehyde-lyase activity [GO:0016832]; magnesium ion binding [GO:0000287]; nickel cation binding [GO:0016151]; cellular aromatic compound metabolic process [GO:0006725]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	cellular aromatic compound metabolic process [GO:0006725]		cytoplasm [GO:0005737]		2-keto-3-deoxy-L-rhamnonate aldolase activity [GO:0106099]; aldehyde-lyase activity [GO:0016832]; magnesium ion binding [GO:0000287]; nickel cation binding [GO:0016151]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d2vx2c__d2zqrf___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; catalytic activity [GO:0003824]; fatty acid metabolic process [GO:0006631]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	fatty acid metabolic process [GO:0006631]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]	enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]
d2vx4a__d3lxab1__1		Metazoa		Chordata		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d2vx5a__d1j0hb3__1				Firmicutes		metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2vx7a__d1fa2a___1		Viridiplantae		Streptophyta		amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]				amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d2vxab__d2vyxe___1			Proteobacteria	Deinococcus-Thermus	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2vxac__d2v18c___1			Proteobacteria	Deinococcus-Thermus	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2vxac__d3oqte___1			Proteobacteria	Actinobacteria	nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2vxad__d3oqti___1			Proteobacteria	Actinobacteria	nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2vxak__d2cz8f___1			Proteobacteria	Deinococcus-Thermus	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2vxic__d3a9qk___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2vxif__d5l8bj1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]
d2vxii__d2yjjh___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d2vxik__d3n1xb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d2vxjh__d1p8ja1__1		Metazoa	Proteobacteria	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	dibasic protein processing [GO:0090472]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular region [GO:0005576]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; trans-Golgi network transport vesicle membrane [GO:0012510]	carbohydrate binding [GO:0030246]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d2vxju__d3k77g___1		Metazoa	Proteobacteria	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]	3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]
d2vxka__d2dpta___1	Fungi		Ascomycota	Proteobacteria	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; leucyltransferase activity [GO:0008914]; transferase activity, transferring amino-acyl groups [GO:0016755]; protein catabolic process [GO:0030163]	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	protein catabolic process [GO:0030163]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]	cytoplasm [GO:0005737]	glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]	leucyltransferase activity [GO:0008914]; transferase activity, transferring amino-acyl groups [GO:0016755]
d2vxla__d4asyd___1	Metazoa		Chordata	Proteobacteria	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]		metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2vxqa__d1n10b1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]; sexual reproduction [GO:0019953]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	sexual reproduction [GO:0019953]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2vxql2_d1pkqb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	signaling receptor binding [GO:0005102]
d2vxsl1_d4kk9f2__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cell-cell signaling [GO:0007267]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cell death [GO:0008219]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d2vxsl2_d4x6ba1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cell-cell signaling [GO:0007267]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cell death [GO:0008219]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytokine activity [GO:0005125]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2vxsm2_d2fjfn1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cell-cell signaling [GO:0007267]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]		apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cell death [GO:0008219]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]	
d2vxsn1_d2f54d1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cell-cell signaling [GO:0007267]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cell death [GO:0008219]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]	cytokine activity [GO:0005125]	
d2vxso1_d3qdgd1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cell-cell signaling [GO:0007267]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cell death [GO:0008219]; cellular response to interleukin-1 [GO:0071347]; cytokine-mediated signaling pathway [GO:0019221]; defense response to fungus [GO:0050832]; fibroblast activation [GO:0072537]; granulocyte migration [GO:0097530]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-17-mediated signaling pathway [GO:0097400]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytokine activity [GO:0005125]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2vxtl2_d5f93c1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]		activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]		cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]	
d2vxul1_d1n7ml1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2vxul2_d4k3gb___1												
d2vxvl1_d3sknb2__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d2vxvl2_d1oaun___1		Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		
d2vxxa__d3oj5l___1			Cyanobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]
d2vxxd__d1uzra___1			Cyanobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2vxxd__d3qd8g1__1			Cyanobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2vy0b__d3ap6c___1		Metazoa	Euryarchaeota	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	carbohydrate metabolic process [GO:0005975]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d2vyab__d1grka___1	Metazoa		Chordata		endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]		acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]	
d2vyoa__d4m1ba___1	Fungi		Microsporidia	Firmicutes	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]
d2vypa2_d3wxjd2__1	Metazoa		Chordata		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d2vyrh__d2ny0b1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d2vyri__d1qlel___1	Metazoa		Chordata	Proteobacteria	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respiratory chain complex IV [GO:0045277]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; aerobic respiration [GO:0009060]; electron transport coupled proton transport [GO:0015990]; oxidative phosphorylation [GO:0006119]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	aerobic respiration [GO:0009060]; electron transport coupled proton transport [GO:0015990]; oxidative phosphorylation [GO:0006119]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respiratory chain complex IV [GO:0045277]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]	cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2vyri__d2cmrl2__1	Metazoa		Chordata		nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]		atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]		nucleoplasm [GO:0005654]; nucleus [GO:0005634]		enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]	
d2vyrj__d1dn0a1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]		atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]		nucleoplasm [GO:0005654]; nucleus [GO:0005634]		enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]	
d2vyrj__d2y9rt___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d2vyrl__d1tzia2__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]
d2vywa__d5nb4g___1				Cyanobacteria		phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]		
d2vyxa__d2vxae___1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2vyxf__d2v19g___1			Deinococcus-Thermus	Deinococcus-Thermus	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2vyxj__d2v19f___1			Deinococcus-Thermus	Deinococcus-Thermus	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2vyxk__d2vxal___1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2vyxl__d3oqtb___1			Deinococcus-Thermus	Actinobacteria	nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2vyya__d2xkga___1	Metazoa	Metazoa	Nemertea (ribbon worms)	Nemertea (ribbon worms)	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2vz2a2_d1ddoa2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d2vz3a3_d5c92a1__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]				extracellular region [GO:0005576]		galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	
d2vzla2_d1ddia2__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	oxidation-reduction process [GO:0055114]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	phycobilisome [GO:0030089]	cytosol [GO:0005829]; sulfite reductase complex (NADPH) [GO:0009337]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NADP+ binding [GO:0070401]; oxidoreductase activity [GO:0016491]; riboflavin reductase (NADPH) activity [GO:0042602]; sulfite reductase (NADPH) activity [GO:0004783]
d2vzla2_d3vo2b2__1		Viridiplantae	Cyanobacteria	Streptophyta	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]	chloroplast [GO:0009507]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d2vzma__d4l49a___1			Actinobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2vzoa1_d4ttgd1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vzob1_d1dp0b3__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vzob2_d2vzua4__1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2vzob4_d1f49b1__1			Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	
d2vzsa1_d3vd3a2__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vzsa3_d3dymd4__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vzsa4_d1jz0e3__1			Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	
d2vzsa4_d2vl4a4__1			Actinobacteria	Bacteroidetes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-mannosidase activity [GO:0004567]
d2vzsb1_d1dp0c1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vzsb1_d4duwa4__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vzsb3_d2vqtb3__1			Actinobacteria	Bacteroidetes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-mannosidase activity [GO:0004567]
d2vzsb5_d4flsa1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	amylosucrase activity [GO:0047669]
d2vzta2_d1hn1c2__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vzta4_d3vdcc4__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vzta5_d3vd3b4__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vztb1_d2b4kb1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d2vztb2_d2vl4b3__1			Actinobacteria	Bacteroidetes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-mannosidase activity [GO:0004567]
d2vztb3_d2diea1__1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2vztb4_d1jz3a1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vztb4_d3t0dc4__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vzua1_d3le0a___1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; cholesterol binding [GO:0015485]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; hemolysis in other organism [GO:0044179]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	hemolysis in other organism [GO:0044179]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cholesterol binding [GO:0015485]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d2vzub1_d3t2oa1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vzub1_d4yw7j___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]
d2vzub4_d3vdcd2__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vzva4_d2je8b1__1			Actinobacteria	Bacteroidetes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-mannosidase activity [GO:0004567]
d2vzva4_d3sepd4__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vzva5_d1f49f2__1			Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	
d2vzvb2_d3t2qc2__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2vzvb3_d5bwfa1__1		Fungi	Actinobacteria	Ascomycota	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2w01b__d1wc4a1__1			Cyanobacteria	Cyanobacteria	integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; phosphorus-oxygen lyase activity [GO:0016849]; cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556]	adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; cyclic nucleotide biosynthetic process [GO:0009190]; protein-chromophore linkage [GO:0018298]	cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556]	cyclic nucleotide biosynthetic process [GO:0009190]; protein-chromophore linkage [GO:0018298]	integral component of membrane [GO:0016021]		identical protein binding [GO:0042802]; phosphorus-oxygen lyase activity [GO:0016849]	adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]
d2w01c__d1u0ha___1		Metazoa	Cyanobacteria	Chordata	integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; phosphorus-oxygen lyase activity [GO:0016849]; cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556]	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	integral component of membrane [GO:0016021]	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; phosphorus-oxygen lyase activity [GO:0016849]	adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d2w07a1_d2mspa___1		Metazoa	Proteobacteria	Nematoda (roundworms)	outer membrane-bounded periplasmic space [GO:0030288]; cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]; identical protein binding [GO:0042802]	cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]		outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]		identical protein binding [GO:0042802]
d2w08a__d2zmka___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]
d2w0db1_d1gkdb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d2w0dc1_d1bqqm___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; intermediate filament cytoskeleton [GO:0045111]; macropinosome [GO:0044354]; melanosome [GO:0042470]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; metalloaminopeptidase activity [GO:0070006]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; astrocyte cell migration [GO:0043615]; branching morphogenesis of an epithelial tube [GO:0048754]; cell motility [GO:0048870]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; endodermal cell differentiation [GO:0035987]; endothelial cell proliferation [GO:0001935]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; head development [GO:0060322]; lung development [GO:0030324]; male gonad development [GO:0008584]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle development [GO:0001541]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of macrophage migration [GO:1905523]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein processing [GO:0010954]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein localization to plasma membrane [GO:1903076]; response to estrogen [GO:0043627]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to odorant [GO:1990834]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; skeletal system development [GO:0001501]; tissue remodeling [GO:0048771]; zymogen activation [GO:0031638]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	angiogenesis [GO:0001525]; astrocyte cell migration [GO:0043615]; branching morphogenesis of an epithelial tube [GO:0048754]; cell motility [GO:0048870]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; endodermal cell differentiation [GO:0035987]; endothelial cell proliferation [GO:0001935]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; head development [GO:0060322]; lung development [GO:0030324]; male gonad development [GO:0008584]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle development [GO:0001541]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of macrophage migration [GO:1905523]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein processing [GO:0010954]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein localization to plasma membrane [GO:1903076]; response to estrogen [GO:0043627]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to odorant [GO:1990834]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; skeletal system development [GO:0001501]; tissue remodeling [GO:0048771]; zymogen activation [GO:0031638]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; intermediate filament cytoskeleton [GO:0045111]; macropinosome [GO:0044354]; melanosome [GO:0042470]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; metalloaminopeptidase activity [GO:0070006]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d2w0dd1_d1go8p2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d2w0fb2_d2htlf1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d2w0ld1_d2p1ye2__1	Metazoa	Metazoa	Chordata	Chordata								
d2w0pb__d1x6la1__1	Metazoa		Chordata	Proteobacteria	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d2w0ra__d3bzsa___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]; protein secretion [GO:0009306]	protein secretion [GO:0009306]	protein secretion [GO:0009306]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]		dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]
d2w0va1_d1j8wd___1			Proteobacteria		cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	
d2w0wa1_d2aecb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cytoplasm [GO:0005737]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d2w0wa2_d2oi7a1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d2w0wa2_d3tiof___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; protein homotrimerization [GO:0070207]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d2w12a__d1dthb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; chemotaxis [GO:0006935]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; collagen catabolic process [GO:0030574]	chemotaxis [GO:0006935]	collagen catabolic process [GO:0030574]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]
d2w13a__d1smpa2__1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; chemotaxis [GO:0006935]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; pathogenesis [GO:0009405]; proteolysis [GO:0006508]	chemotaxis [GO:0006935]	pathogenesis [GO:0009405]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d2w1la__d221la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2w1ma__d2rbpa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2w1ya__d5xpea___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2w23a__d1bj9a___1	Fungi	Fungi	Basidiomycota	Ascomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2w2ba__d3nadb___1			Firmicutes	Firmicutes	carboxy-lyase activity [GO:0016831]	carboxy-lyase activity [GO:0016831]					carboxy-lyase activity [GO:0016831]	carboxy-lyase activity [GO:0016831]
d2w2bb__d2w2fb___1			Firmicutes	Firmicutes	carboxy-lyase activity [GO:0016831]	carboxy-lyase activity [GO:0016831]					carboxy-lyase activity [GO:0016831]	carboxy-lyase activity [GO:0016831]
d2w2fc__d2wsjb___1			Firmicutes	Firmicutes	carboxy-lyase activity [GO:0016831]	carboxy-lyase activity [GO:0016831]					carboxy-lyase activity [GO:0016831]	carboxy-lyase activity [GO:0016831]
d2w2fd__d5fenb___1		Metazoa	Firmicutes	Chordata	carboxy-lyase activity [GO:0016831]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]		epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]		cytosol [GO:0005829]	carboxy-lyase activity [GO:0016831]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d2w37b1_d3m5da1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine catabolic process to ornithine [GO:0019547]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]
d2w37c2_d1ortc1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	arginine catabolic process to ornithine [GO:0019547]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d2w3aa__d1re7a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d2w3aa__d3zpca2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d2w3ab__d4ky8d1__1	Metazoa		Chordata		cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	
d2w3mb__d4osgc___1	Metazoa		Chordata		cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	
d2w3re4_d1n62c1__1			Proteobacteria	Proteobacteria	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2w3rf1_d3nrzl1__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d2w3rg3_d5fxpb1__1			Proteobacteria	Actinobacteria	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]					molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d2w3rg4_d3nvzk2__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d2w3rh1_d3nvvl1__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d2w3sa4_d1t3qc1__1			Proteobacteria	Proteobacteria	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	oxidoreductase activity [GO:0016491]					molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	oxidoreductase activity [GO:0016491]
d2w3sb1_d1qj2h3__1			Proteobacteria		molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]						molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	
d2w3sc3_d1w1oa2__1		Viridiplantae	Proteobacteria	Streptophyta	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	extracellular space [GO:0005615]; cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]		cytokinin metabolic process [GO:0009690]		extracellular space [GO:0005615]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]
d2w3se1_d5oefa1__1			Proteobacteria	Firmicutes	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]					molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]
d2w3se4_d3ax9b3__1		Metazoa	Proteobacteria	Chordata	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d2w3wa__d1dr2a___1		Metazoa	Actinobacteria	Chordata	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d2w3wa__d4elbc1__1			Actinobacteria	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d2w40a2_d4m63d2__1		Metazoa	Apicomplexa	Arthropoda	mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	mitochondrion [GO:0005739]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATP binding [GO:0005524]
d2w40b2_d2qwlb1__1		Metazoa	Apicomplexa	Chordata	mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	mitochondrion [GO:0005739]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d2w40c2_d4f9oa1__1		Metazoa	Apicomplexa	Chordata	mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d2w41a1_d1nmda2__1		Metazoa	Apicomplexa	Chordata	mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	mitochondrion [GO:0005739]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d2w41b1_d1glfy2__1			Apicomplexa	Proteobacteria	mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	mitochondrion [GO:0005739]	cytosol [GO:0005829]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d2w43b__d3e81d___1			Crenarchaeota	Bacteroidetes	(S)-2-haloacid dehalogenase activity [GO:0018784]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]			(S)-2-haloacid dehalogenase activity [GO:0018784]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d2w4ca__d3mzid___1	Metazoa		Chordata	Cyanobacteria	acylphosphatase activity [GO:0003998]; phosphate-containing compound metabolic process [GO:0006796]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	phosphate-containing compound metabolic process [GO:0006796]				acylphosphatase activity [GO:0003998]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]
d2w4db__d1w2ib___1			Euryarchaeota	Euryarchaeota	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]					acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]
d2w4db__d2hfod___1			Euryarchaeota	Cyanobacteria	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]					acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]
d2w4dc__d3tnva___1			Euryarchaeota	Euryarchaeota	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]					acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]
d2w4de__d2acya___1		Metazoa	Euryarchaeota	Chordata	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	acylphosphatase activity [GO:0003998]					acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	acylphosphatase activity [GO:0003998]
d2w4de__d2hfni___1			Euryarchaeota	Cyanobacteria	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]					acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]
d2w4fa__d2kawa___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; myelin sheath abaxonal region [GO:0035748]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Scrib-APC-beta-catenin complex [GO:0034750]; synapse [GO:0045202]; cadherin binding [GO:0045296]; activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; auditory receptor cell stereocilium organization [GO:0060088]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; post-anal tail morphogenesis [GO:0036342]; protein localization to adherens junction [GO:0071896]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; wound healing [GO:0042060]	axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; Rac GTPase binding [GO:0048365]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; collateral sprouting [GO:0048668]; convergent extension involved in neural plate elongation [GO:0022007]; convergent extension involved in organogenesis [GO:0060029]; cytoplasmic microtubule organization [GO:0031122]; dendrite morphogenesis [GO:0048813]; dendritic spine morphogenesis [GO:0060997]; intracellular signal transduction [GO:0035556]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse organization [GO:0099173]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein localization to microtubule [GO:0035372]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cellular protein localization [GO:1903827]; regulation of neurotransmitter levels [GO:0001505]; regulation of protein phosphorylation [GO:0001932]; regulation of synaptic vesicle exocytosis [GO:2000300]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; social behavior [GO:0035176]; synapse organization [GO:0050808]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; auditory receptor cell stereocilium organization [GO:0060088]; cell-cell adhesion [GO:0098609]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; post-anal tail morphogenesis [GO:0036342]; protein localization to adherens junction [GO:0071896]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; wound healing [GO:0042060]	axon extension [GO:0048675]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; collateral sprouting [GO:0048668]; convergent extension involved in neural plate elongation [GO:0022007]; convergent extension involved in organogenesis [GO:0060029]; cytoplasmic microtubule organization [GO:0031122]; dendrite morphogenesis [GO:0048813]; dendritic spine morphogenesis [GO:0060997]; intracellular signal transduction [GO:0035556]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse organization [GO:0099173]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein localization to microtubule [GO:0035372]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cellular protein localization [GO:1903827]; regulation of neurotransmitter levels [GO:0001505]; regulation of protein phosphorylation [GO:0001932]; regulation of synaptic vesicle exocytosis [GO:2000300]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; social behavior [GO:0035176]; synapse organization [GO:0050808]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	basolateral plasma membrane [GO:0016323]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; extracellular exosome [GO:0070062]; extrinsic component of postsynaptic density membrane [GO:0099147]; glutamatergic synapse [GO:0098978]; lamellipodium [GO:0030027]; myelin sheath abaxonal region [GO:0035748]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Scrib-APC-beta-catenin complex [GO:0034750]; synapse [GO:0045202]	axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]	cadherin binding [GO:0045296]	beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; Rac GTPase binding [GO:0048365]
d2w4le__d5k81d___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dCMP deaminase activity [GO:0004132]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; dTMP biosynthetic process [GO:0006231]; dUMP biosynthetic process [GO:0006226]; nucleobase-containing small molecule interconversion [GO:0015949]; pyrimidine nucleotide metabolic process [GO:0006220]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; innate immune response [GO:0045087]	dTMP biosynthetic process [GO:0006231]; dUMP biosynthetic process [GO:0006226]; nucleobase-containing small molecule interconversion [GO:0015949]; pyrimidine nucleotide metabolic process [GO:0006220]	base conversion or substitution editing [GO:0016553]; innate immune response [GO:0045087]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		dCMP deaminase activity [GO:0004132]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]
d2w4ma1_d1k1ef___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; N-acylneuraminate-9-phosphatase activity [GO:0050124]; carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine biosynthetic process [GO:0006045]; N-acetylneuraminate biosynthetic process [GO:0046380]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine biosynthetic process [GO:0006045]; N-acetylneuraminate biosynthetic process [GO:0046380]	lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]		N-acylneuraminate-9-phosphatase activity [GO:0050124]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d2w4pa__d2hfnd___1	Metazoa		Chordata	Cyanobacteria	acylphosphatase activity [GO:0003998]; phosphate-containing compound metabolic process [GO:0006796]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	phosphate-containing compound metabolic process [GO:0006796]				acylphosphatase activity [GO:0003998]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]
d2w4xa3_d2x0yb3__1			Bacteroidetes	Firmicutes	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d2w5ka__d3ln8a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]		endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]
d2w60b1_d2gk0a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2w60b2_d3owei___1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2w60b2_d3vwkb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2w6ma2_d1cs0a5__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2w6mb3_d4mv3a3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2w6na1_d5ca0f1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]; tubulin binding [GO:0015631]; microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	tubulin binding [GO:0015631]
d2w6na2_d1ce8g5__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2w6nb1_d1pk8a1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	anchored component of synaptic vesicle membrane [GO:0098993]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of synaptic vesicle membrane [GO:0098850]; Golgi apparatus [GO:0005794]; intracellular organelle [GO:0043229]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; synaptonemal complex [GO:0000795]; terminal bouton [GO:0043195]; actin binding [GO:0003779]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; neuron development [GO:0048666]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle cycle [GO:0098693]; synapse organization [GO:0050808]; synaptic vesicle clustering [GO:0097091]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	neuron development [GO:0048666]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle cycle [GO:0098693]; synapse organization [GO:0050808]; synaptic vesicle clustering [GO:0097091]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	anchored component of synaptic vesicle membrane [GO:0098993]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of synaptic vesicle membrane [GO:0098850]; Golgi apparatus [GO:0005794]; intracellular organelle [GO:0043229]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; synaptonemal complex [GO:0000795]; terminal bouton [GO:0043195]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	actin binding [GO:0003779]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]
d2w6nb3_d1kjqb1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d2w6oc1_d5d8dd1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2w6qa3_d2ip4a3__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d2w6qb3_d2qk4b3__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d2w6vc__d1jzkc___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2w6vc__d1yhun___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2w70a1_d2yrwa1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d2w70a2_d2nu7e2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d2w70b1_d2r87a1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]; 'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; ligase activity, forming carbon-nitrogen bonds [GO:0016879]; magnesium ion binding [GO:0000287]
d2w71a1_d5d8de1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2w72a__d2c7ja___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2w72c__d1yhuu___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2w73b__d3fs7a___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]
d2w73e__d2mjwd___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; advanced glycation end-product receptor activity [GO:0050785]; amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; S100 protein binding [GO:0044548]; scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; astrocyte activation [GO:0048143]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; glucose mediated signaling pathway [GO:0010255]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of blood circulation [GO:1903523]; negative regulation of connective tissue replacement involved in inflammatory response wound healing [GO:1904597]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of long-term synaptic potentiation [GO:1900272]; neuron projection development [GO:0031175]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein localization to membrane [GO:0072657]; regulation of CD4-positive, alpha-beta T cell activation [GO:2000514]; regulation of DNA binding [GO:0051101]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of p38MAPK cascade [GO:1900744]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell mediated cytotoxicity [GO:0001914]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to wounding [GO:0009611]; transcytosis [GO:0045056]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	astrocyte activation [GO:0048143]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; glucose mediated signaling pathway [GO:0010255]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of blood circulation [GO:1903523]; negative regulation of connective tissue replacement involved in inflammatory response wound healing [GO:1904597]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of long-term synaptic potentiation [GO:1900272]; neuron projection development [GO:0031175]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein localization to membrane [GO:0072657]; regulation of CD4-positive, alpha-beta T cell activation [GO:2000514]; regulation of DNA binding [GO:0051101]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of p38MAPK cascade [GO:1900744]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell mediated cytotoxicity [GO:0001914]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to wounding [GO:0009611]; transcytosis [GO:0045056]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	advanced glycation end-product receptor activity [GO:0050785]; amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; S100 protein binding [GO:0044548]; scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]
d2w7ja__d3fz7d___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]
d2w7ub__d2g81e___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]		digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2w7ud__d2bdie___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]		amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2w88b__d1ndrc1__1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2w88c__d4enza4__1		Metazoa	Cyanobacteria	Chordata	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]		cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	thylakoid membrane [GO:0042651]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d2w8bf2_d2hqsa1__1			Proteobacteria	Proteobacteria	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]; cell cycle [GO:0007049]; cell division [GO:0051301]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]; cell cycle [GO:0007049]; cell division [GO:0051301]	cell cycle [GO:0007049]; cell division [GO:0051301]	cell cycle [GO:0007049]; cell division [GO:0051301]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]		
d2w8bh1_d4b5ca___1			Proteobacteria	Proteobacteria	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]; cell cycle [GO:0007049]; cell division [GO:0051301]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell cycle [GO:0007049]; cell division [GO:0051301]	cell cycle [GO:0007049]; cell division [GO:0051301]	cell cycle [GO:0007049]; cell division [GO:0051301]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]		
d2w8ca__d3erxb___1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2w8ca__d3t6va1__1		Fungi	Cyanobacteria	Basidiomycota	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]			thylakoid membrane [GO:0042651]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2w8fa__d3sq6g___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d2w8fb__d3sq6a___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d2w8fg__d4zk1e1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2w8fj__d3wthe1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2w8gc__d1uw6p___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2w8gd__d5tsfa1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2w8na__d3iwkh___1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein homodimerization activity [GO:0042803]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; acetate metabolic process [GO:0006083]; central nervous system development [GO:0007417]; galactosylceramide metabolic process [GO:0006681]; gamma-aminobutyric acid catabolic process [GO:0009450]; glucose metabolic process [GO:0006006]; glutamate metabolic process [GO:0006536]; glutamine metabolic process [GO:0006541]; glutathione metabolic process [GO:0006749]; glycerophospholipid metabolic process [GO:0006650]; neurotransmitter catabolic process [GO:0042135]; post-embryonic development [GO:0009791]; protein homotetramerization [GO:0051289]; respiratory electron transport chain [GO:0022904]; short-chain fatty acid metabolic process [GO:0046459]; succinate metabolic process [GO:0006105]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	acetate metabolic process [GO:0006083]; central nervous system development [GO:0007417]; galactosylceramide metabolic process [GO:0006681]; gamma-aminobutyric acid catabolic process [GO:0009450]; glucose metabolic process [GO:0006006]; glutamate metabolic process [GO:0006536]; glutamine metabolic process [GO:0006541]; glutathione metabolic process [GO:0006749]; glycerophospholipid metabolic process [GO:0006650]; neurotransmitter catabolic process [GO:0042135]; post-embryonic development [GO:0009791]; protein homotetramerization [GO:0051289]; respiratory electron transport chain [GO:0022904]; short-chain fatty acid metabolic process [GO:0046459]; succinate metabolic process [GO:0006105]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		protein homodimerization activity [GO:0042803]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]
d2w8pa__d1o05f___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein homodimerization activity [GO:0042803]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; acetate metabolic process [GO:0006083]; central nervous system development [GO:0007417]; galactosylceramide metabolic process [GO:0006681]; gamma-aminobutyric acid catabolic process [GO:0009450]; glucose metabolic process [GO:0006006]; glutamate metabolic process [GO:0006536]; glutamine metabolic process [GO:0006541]; glutathione metabolic process [GO:0006749]; glycerophospholipid metabolic process [GO:0006650]; neurotransmitter catabolic process [GO:0042135]; post-embryonic development [GO:0009791]; protein homotetramerization [GO:0051289]; respiratory electron transport chain [GO:0022904]; short-chain fatty acid metabolic process [GO:0046459]; succinate metabolic process [GO:0006105]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	acetate metabolic process [GO:0006083]; central nervous system development [GO:0007417]; galactosylceramide metabolic process [GO:0006681]; gamma-aminobutyric acid catabolic process [GO:0009450]; glucose metabolic process [GO:0006006]; glutamate metabolic process [GO:0006536]; glutamine metabolic process [GO:0006541]; glutathione metabolic process [GO:0006749]; glycerophospholipid metabolic process [GO:0006650]; neurotransmitter catabolic process [GO:0042135]; post-embryonic development [GO:0009791]; protein homotetramerization [GO:0051289]; respiratory electron transport chain [GO:0022904]; short-chain fatty acid metabolic process [GO:0046459]; succinate metabolic process [GO:0006105]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	protein homodimerization activity [GO:0042803]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2w8qa__d4h80b___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein homodimerization activity [GO:0042803]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; acetate metabolic process [GO:0006083]; central nervous system development [GO:0007417]; galactosylceramide metabolic process [GO:0006681]; gamma-aminobutyric acid catabolic process [GO:0009450]; glucose metabolic process [GO:0006006]; glutamate metabolic process [GO:0006536]; glutamine metabolic process [GO:0006541]; glutathione metabolic process [GO:0006749]; glycerophospholipid metabolic process [GO:0006650]; neurotransmitter catabolic process [GO:0042135]; post-embryonic development [GO:0009791]; protein homotetramerization [GO:0051289]; respiratory electron transport chain [GO:0022904]; short-chain fatty acid metabolic process [GO:0046459]; succinate metabolic process [GO:0006105]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	acetate metabolic process [GO:0006083]; central nervous system development [GO:0007417]; galactosylceramide metabolic process [GO:0006681]; gamma-aminobutyric acid catabolic process [GO:0009450]; glucose metabolic process [GO:0006006]; glutamate metabolic process [GO:0006536]; glutamine metabolic process [GO:0006541]; glutathione metabolic process [GO:0006749]; glycerophospholipid metabolic process [GO:0006650]; neurotransmitter catabolic process [GO:0042135]; post-embryonic development [GO:0009791]; protein homotetramerization [GO:0051289]; respiratory electron transport chain [GO:0022904]; short-chain fatty acid metabolic process [GO:0046459]; succinate metabolic process [GO:0006105]	aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	protein homodimerization activity [GO:0042803]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]	3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]
d2w8za2_d1f0yb1__1		Metazoa	Firmicutes	Chordata	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d2w8za2_d2grac2__1		Metazoa	Firmicutes	Chordata	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d2w8zb1_d2yfhe2__1			Firmicutes	Proteobacteria	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	glutamate biosynthetic process [GO:0006537]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]
d2w8zb2_d1pgpa1__1		Metazoa	Firmicutes	Chordata	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]	D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]
d2w90a1_d5k4vc1__1						coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]						coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]
d2w90a2_d4pzed2__1				Proteobacteria		3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]		fatty acid metabolic process [GO:0006631]				3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d2w90b2_d2uyyc2__1		Metazoa		Chordata		cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]		positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]		cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]		chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491]
d2w93a1_d1mczb2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2w93b2_d5deic2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2w93c2_d1n0ha1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2w93d3_d1mcze2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2w93d3_d2g1ib3__1	Fungi		Ascomycota		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	
d2w9dl2_d1ndgb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2w9ea__d2fj3a___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d2w9el1_d3pxjd2__1	Metazoa	Metazoa	Chordata	Arthropoda	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d2w9ha__d4x5gb1__1			Firmicutes	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d2w9lb__d1h8na1__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2w9lc__d1zruc1__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	virus tail, baseplate [GO:0098025]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2w9lg__d1lo2y1__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2w9lh__d4xqbc___1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	viral capsid [GO:0019028]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	metal ion binding [GO:0046872]
d2w9li__d3u6xh2__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	virus tail, baseplate [GO:0098025]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2w9lj__d1yejh1__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2w9lt__d5vkhb2__1	Metazoa		Chordata	Actinobacteria	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	voltage-gated potassium channel complex [GO:0008076]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d2w9pd__d3pxma___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cysteine-type endopeptidase inhibitor activity [GO:0004869]						cysteine-type endopeptidase inhibitor activity [GO:0004869]	
d2w9ph__d3l0ra1__1	Viridiplantae	Metazoa	Streptophyta	Arthropoda	cysteine-type endopeptidase inhibitor activity [GO:0004869]	cysteine-type endopeptidase inhibitor activity [GO:0004869]					cysteine-type endopeptidase inhibitor activity [GO:0004869]	cysteine-type endopeptidase inhibitor activity [GO:0004869]
d2w9pk__d1mnla___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cysteine-type endopeptidase inhibitor activity [GO:0004869]						cysteine-type endopeptidase inhibitor activity [GO:0004869]	
d2w9pl__d1a90a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cysteine-type endopeptidase inhibitor activity [GO:0004869]	extracellular space [GO:0005615]; cysteine-type endopeptidase inhibitor activity [GO:0004869]				extracellular space [GO:0005615]	cysteine-type endopeptidase inhibitor activity [GO:0004869]	cysteine-type endopeptidase inhibitor activity [GO:0004869]
d2w9ra__d4ykaa___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	
d2w9sc__d2c2sa___1		Metazoa	Firmicutes	Chordata	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d2w9sd__d1rx9a___1			Firmicutes	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d2w9sd__d3e0ba1__1			Firmicutes	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d2w9se__d2jyba___1			Firmicutes	Euryarchaeota	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d2wa1b__d2xbma___1					host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2wa2b__d1ri5a___1		Fungi		Microsporidia	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	nucleus [GO:0005634]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; RNA binding [GO:0003723]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]	mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; RNA binding [GO:0003723]
d2wa6a1_d1wjoa1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; bone development [GO:0060348]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; bone development [GO:0060348]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d2wa7a1_d2d87a1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; filamentous actin [GO:0031941]; microtubule organizing center [GO:0005815]; actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; actin cytoskeleton organization [GO:0030036]; muscle organ development [GO:0007517]; smooth muscle contraction [GO:0006939]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	actin cytoskeleton organization [GO:0030036]; muscle organ development [GO:0007517]; smooth muscle contraction [GO:0006939]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; filamentous actin [GO:0031941]; microtubule organizing center [GO:0005815]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]	actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]
d2waha2_d5m00h2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2wb5a2_d1fh9a___1			Firmicutes	Actinobacteria	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]
d2wb9a1_d4x43b___1	Metazoa		Platyhelminthes	Proteobacteria	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutathione transferase activity [GO:0004364]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2wb9a2_d1vf3b2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2wbgb__d4y7ea1__1			Thermotogae	Actinobacteria	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]
d2wbia2_d1jqib1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; peroxisome [GO:0005777]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; long-chain-acyl-CoA dehydrogenase activity [GO:0004466]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; very-long-chain-acyl-CoA dehydrogenase activity [GO:0017099]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; protein homotetramerization [GO:0051289]; response to glucocorticoid [GO:0051384]; response to starvation [GO:0042594]	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; protein homotetramerization [GO:0051289]; response to glucocorticoid [GO:0051384]; response to starvation [GO:0042594]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; peroxisome [GO:0005777]	mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; long-chain-acyl-CoA dehydrogenase activity [GO:0004466]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; very-long-chain-acyl-CoA dehydrogenase activity [GO:0017099]	acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]
d2wbia2_d4irne2__1	Metazoa		Chordata	Cyanobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; peroxisome [GO:0005777]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; long-chain-acyl-CoA dehydrogenase activity [GO:0004466]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; very-long-chain-acyl-CoA dehydrogenase activity [GO:0017099]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]		mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; peroxisome [GO:0005777]		acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; long-chain-acyl-CoA dehydrogenase activity [GO:0004466]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; very-long-chain-acyl-CoA dehydrogenase activity [GO:0017099]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d2wbja1_d4z7ua1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	nutrient reservoir activity [GO:0045735]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	nutrient reservoir activity [GO:0045735]
d2wbja2_d3euub___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2wbjc2_d4a6ya1__1	Metazoa		Chordata		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	
d2wbje2_d1t0mb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d2wbjg1_d1u8la2__1	Metazoa		Chordata		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	
d2wbjg1_d4rgnl1__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	extracellular region [GO:0005576]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d2wbka2_d1jz2a1__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2wbka3_d2gsja___1			Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]	
d2wbka4_d1jyyg1__1			Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]	
d2wbkb2_d1bglh1__1			Bacteroidetes		beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]		carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]				beta-mannosidase activity [GO:0004567]	
d2wbkb4_d1jz7a2__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2wbkb4_d3t08b2__1			Bacteroidetes	Proteobacteria	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-mannosidase activity [GO:0004567]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2wbma1_d1t95a2__1			Euryarchaeota	Euryarchaeota	mature ribosome assembly [GO:0042256]	mature ribosome assembly [GO:0042256]	mature ribosome assembly [GO:0042256]	mature ribosome assembly [GO:0042256]				
d2wbmb3_d1zm4a5__1			Euryarchaeota	Proteobacteria	mature ribosome assembly [GO:0042256]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	mature ribosome assembly [GO:0042256]					NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d2wbvd__d3bq4a___1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	viral capsid [GO:0019028]		
d2wbve__d1h7za___1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]		
d2wbvf__d3u6xj2__1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]		
d2wbwa__d2bsdb1__1	Metazoa		Chordata		acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	virus tail, baseplate [GO:0098025]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	
d2wc1a__d1qrdb___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	nitrogen fixation [GO:0009399]	aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]
d2wc3b__d1wzka3__1			Thermotogae	Firmicutes	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2wc4a__d1uwra___1			Thermotogae	Crenarchaeota	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]
d2wc4b__d1dwfm___1		Viridiplantae	Thermotogae	Streptophyta	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]		vacuole [GO:0005773]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]
d2wc5a__d3b88b___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]	odorant binding [GO:0005549]	dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]
d2wcfa1_d2o5ga___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; myosin light chain kinase activity [GO:0004687]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	cytosol [GO:0005829]; membrane [GO:0016020]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; myosin light chain kinase activity [GO:0004687]
d2wcfb1_d3vrqa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	membrane raft [GO:0045121]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]; cell surface receptor signaling pathway [GO:0007166]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of MAP kinase activity [GO:0043407]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	cell surface receptor signaling pathway [GO:0007166]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of MAP kinase activity [GO:0043407]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	membrane raft [GO:0045121]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; epidermal growth factor receptor binding [GO:0005154]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]
d2wcfc1_d2mjwd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; advanced glycation end-product receptor activity [GO:0050785]; amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; S100 protein binding [GO:0044548]; scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; astrocyte activation [GO:0048143]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; glucose mediated signaling pathway [GO:0010255]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of blood circulation [GO:1903523]; negative regulation of connective tissue replacement involved in inflammatory response wound healing [GO:1904597]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of long-term synaptic potentiation [GO:1900272]; neuron projection development [GO:0031175]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein localization to membrane [GO:0072657]; regulation of CD4-positive, alpha-beta T cell activation [GO:2000514]; regulation of DNA binding [GO:0051101]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of p38MAPK cascade [GO:1900744]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell mediated cytotoxicity [GO:0001914]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to wounding [GO:0009611]; transcytosis [GO:0045056]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	astrocyte activation [GO:0048143]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; glucose mediated signaling pathway [GO:0010255]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of blood circulation [GO:1903523]; negative regulation of connective tissue replacement involved in inflammatory response wound healing [GO:1904597]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of long-term synaptic potentiation [GO:1900272]; neuron projection development [GO:0031175]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein localization to membrane [GO:0072657]; regulation of CD4-positive, alpha-beta T cell activation [GO:2000514]; regulation of DNA binding [GO:0051101]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of p38MAPK cascade [GO:1900744]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell mediated cytotoxicity [GO:0001914]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to wounding [GO:0009611]; transcytosis [GO:0045056]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	advanced glycation end-product receptor activity [GO:0050785]; amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; S100 protein binding [GO:0044548]; scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]
d2wcia__d4xrad___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	thioredoxin peroxidase activity [GO:0008379]
d2wcja__d3bfba___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	odorant binding [GO:0005549]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]				odorant binding [GO:0005549]	odorant binding [GO:0005549]
d2wcja__d4fqtb___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	odorant binding [GO:0005549]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]				odorant binding [GO:0005549]	odorant binding [GO:0005549]
d2wcvd__d4a34j___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; fucose binding [GO:0042806]; L-fucose mutarotase activity [GO:0036373]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; L-fucose metabolic process [GO:0042354]	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]; monosaccharide metabolic process [GO:0005996]	fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; L-fucose metabolic process [GO:0042354]	monosaccharide metabolic process [GO:0005996]	cytoplasm [GO:0005737]		fucose binding [GO:0042806]; L-fucose mutarotase activity [GO:0036373]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]
d2wcwa__d2wcza___1			Euryarchaeota	Euryarchaeota	crossover junction endodeoxyribonuclease activity [GO:0008821]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]	crossover junction endodeoxyribonuclease activity [GO:0008821]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]			crossover junction endodeoxyribonuclease activity [GO:0008821]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]	crossover junction endodeoxyribonuclease activity [GO:0008821]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]
d2wcza__d3v21h___1			Euryarchaeota	Firmicutes	crossover junction endodeoxyribonuclease activity [GO:0008821]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]	endonuclease activity [GO:0004519]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]				crossover junction endodeoxyribonuclease activity [GO:0008821]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]	endonuclease activity [GO:0004519]
d2wd4a__d1ccba___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	chloroplast [GO:0009507]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2wd4a__d1eqhb1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d2wdqj1_d3nvyj1__1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	xanthine catabolic process [GO:0009115]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d2wdub1_d2ljrb2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]		glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2wdzd__d1ky5b1__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]
d2we0a2_d3p48a___1		Fungi		Ascomycota	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUTP metabolic process [GO:0046080]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]	dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2we1a1_d2v9xg___1				Proteobacteria	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]		cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d2we3a2_d1f7qb___1					dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dUTP metabolic process [GO:0046080]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]			dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d2we3a2_d3hhqs___1		Fungi		Ascomycota	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUTP metabolic process [GO:0046080]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]	dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2we5a__d1b7bd___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]; arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]; arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]	ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]
d2weba__d3uhlb___1	Fungi		Ascomycota		extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2weld__d5i8na___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; chemokine production [GO:0032602]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; modification of morphology or physiology of other organism [GO:0035821]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of cytoskeleton organization [GO:0051493]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cell [GO:0005623]; cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	antioxidant activity [GO:0016209]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d2wfcb1_d3tjfb___1	Metazoa	Metazoa	Annelida	Chordata	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d2wfcb1_d4naxa1__1	Metazoa		Annelida	Proteobacteria	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	transferase activity [GO:0016740]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]		peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	transferase activity [GO:0016740]
d2wfha__d3g3ae___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; GTPase inhibitor activity [GO:0005095]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; laminin-1 binding [GO:0043237]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; Roundabout binding [GO:0048495]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; cellular response to hormone stimulus [GO:0032870]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; induction of negative chemotaxis [GO:0050929]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; pulmonary valve morphogenesis [GO:0003184]; response to cortisol [GO:0051414]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; cellular response to hormone stimulus [GO:0032870]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; induction of negative chemotaxis [GO:0050929]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of monocyte chemotaxis [GO:0090027]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; pulmonary valve morphogenesis [GO:0003184]; response to cortisol [GO:0051414]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; GTPase inhibitor activity [GO:0005095]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; laminin-1 binding [GO:0043237]; protein homodimerization activity [GO:0042803]; proteoglycan binding [GO:0043394]; Roundabout binding [GO:0048495]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2wfma__d3dyva___1	Viridiplantae		Streptophyta	Firmicutes	polyneuridine-aldehyde esterase activity [GO:0050529]; alkaloid metabolic process [GO:0009820]	carboxylic ester hydrolase activity [GO:0052689]	alkaloid metabolic process [GO:0009820]				polyneuridine-aldehyde esterase activity [GO:0050529]	carboxylic ester hydrolase activity [GO:0052689]
d2wfmd__d1scia___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	polyneuridine-aldehyde esterase activity [GO:0050529]; alkaloid metabolic process [GO:0009820]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	alkaloid metabolic process [GO:0009820]				polyneuridine-aldehyde esterase activity [GO:0050529]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]
d2wfza__d1wb6b2__1	Metazoa		Chordata	Firmicutes	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	cellulosome [GO:0043263]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	xylan catabolic process [GO:0045493]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	cellulosome [GO:0043263]	acetylcholinesterase activity [GO:0003990]	endo-1,4-beta-xylanase activity [GO:0031176]
d2wgda2_d2rjta1__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d2wgea1_d1tqyh1__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2wgfa2_d2ahba2__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d2wgfc1_d2byxa1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2wgfd2_d2vbac2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2wgfe1_d1u6sa2__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d2wgfe2_d1hnda2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2wgfe2_d1oeqa4__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]		fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	
d2wgff1_d5f38d2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; acetoacetic acid catabolic process [GO:0043442]; fatty acid beta-oxidation [GO:0006635]; protein homotetramerization [GO:0051289]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	acetoacetic acid catabolic process [GO:0043442]; fatty acid beta-oxidation [GO:0006635]; protein homotetramerization [GO:0051289]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	acetyl-CoA C-acetyltransferase activity [GO:0003985]; acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d2wgff2_d2gyoa1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2wgfh1_d2aq7d2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2wgfh2_d1zowd1__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2wgga1_d2eftb2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2wgga1_d4jard2__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	polyketide synthase complex [GO:0034081]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	polyketide synthase complex [GO:0034081]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2wgga2_d1kasa1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d2wggb2_d1oeqa3__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]		fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	
d2wgge2_d1ulqf2__1			Actinobacteria	Deinococcus-Thermus	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2wggf2_d2iwya1__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2wggg2_d2qo1b1__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d2wggh1_d1afwb2__1		Fungi	Actinobacteria	Ascomycota	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	mitochondrial intermembrane space [GO:0005758]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acetyl-CoA C-acyltransferase activity [GO:0003988]; mRNA binding [GO:0003729]; fatty acid beta-oxidation [GO:0006635]; phenylacetate catabolic process [GO:0010124]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	fatty acid beta-oxidation [GO:0006635]; phenylacetate catabolic process [GO:0010124]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	mitochondrial intermembrane space [GO:0005758]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	acetyl-CoA C-acyltransferase activity [GO:0003988]; mRNA binding [GO:0003729]
d2wggh2_d1m1tc2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2wgqa2_d3amoa2__1			Proteobacteria	Actinobacteria	periplasmic space [GO:0042597]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	amine metabolic process [GO:0009308]	periplasmic space [GO:0042597]		aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d2wgqa3_d2e2va3__1			Proteobacteria	Actinobacteria	periplasmic space [GO:0042597]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; L-phenylalanine catabolic process [GO:0006559]; oxidation-reduction process [GO:0055114]; phenylethylamine catabolic process [GO:0019607]	amine metabolic process [GO:0009308]	periplasmic space [GO:0042597]		aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d2wgta__d2wbvd___1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	viral capsid [GO:0019028]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	metal ion binding [GO:0046872]	
d2wgtb__d2j1kd___1		Metazoa		Chordata	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	viral capsid [GO:0019028]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2wgub__d2j2jb___1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	viral capsid [GO:0019028]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	metal ion binding [GO:0046872]	
d2wh5a__d5h3ga1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	cytosol [GO:0005829]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]				cytosol [GO:0005829]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]
d2wh5b__d2fj9a___1	Metazoa	Metazoa	Chordata	Chordata	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; perinuclear endoplasmic reticulum [GO:0097038]; benzodiazepine receptor binding [GO:0030156]; lipid binding [GO:0008289]; long-chain fatty acyl-CoA binding [GO:0036042]; protein dimerization activity [GO:0046983]; acyl-CoA metabolic process [GO:0006637]; phosphatidylcholine acyl-chain remodeling [GO:0036151]		acyl-CoA metabolic process [GO:0006637]; phosphatidylcholine acyl-chain remodeling [GO:0036151]		endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; perinuclear endoplasmic reticulum [GO:0097038]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	benzodiazepine receptor binding [GO:0030156]; lipid binding [GO:0008289]; long-chain fatty acyl-CoA binding [GO:0036042]; protein dimerization activity [GO:0046983]
d2wh5d__d1st7a___1	Metazoa	Fungi	Chordata	Ascomycota	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; lipid binding [GO:0008289]; long-chain fatty acyl-CoA binding [GO:0036042]; chronological cell aging [GO:0001300]; very long-chain fatty acid biosynthetic process [GO:0042761]		chronological cell aging [GO:0001300]; very long-chain fatty acid biosynthetic process [GO:0042761]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	lipid binding [GO:0008289]; long-chain fatty acyl-CoA binding [GO:0036042]
d2wh5e__d3flva1__1	Metazoa	Metazoa	Chordata	Chordata	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]; autophagy of peroxisome [GO:0030242]; fatty acid catabolic process [GO:0009062]		autophagy of peroxisome [GO:0030242]; fatty acid catabolic process [GO:0009062]		integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]
d2whbd2_d2phga1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2whha1_d5p1aa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	aspartic-type endopeptidase activity [GO:0004190]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2whia1_d1htqv1__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d2whia2_d1htqi2__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d2whia2_d4lnfl2__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d2whib1_d3qajf1__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	
d2whic2_d4lnik2__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d2whie2_d1htqg2__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d2whif1_d1fpyh1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d2whja1_d4w7wa1__1			Firmicutes	Proteobacteria	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			mannan endo-1,4-beta-mannosidase activity [GO:0016985]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2whwa__d5ibha___1			Actinobacteria	Actinobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]
d2whya1_d5vq4d___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2whza__d1pwpa2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]		negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d2wi0a__d3hoab___1			Firmicutes	Deinococcus-Thermus	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metallocarboxypeptidase activity [GO:0004181]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metallocarboxypeptidase activity [GO:0004181]
d2wi6a__d1zxma1__1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; viral integration complex [GO:0019035]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; DNA-dependent ATPase activity [GO:0008094]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; magnesium ion binding [GO:0000287]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]; apoptotic chromosome condensation [GO:0030263]; cellular response to DNA damage stimulus [GO:0006974]; chromosome segregation [GO:0007059]; DNA ligation [GO:0006266]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; female meiotic nuclear division [GO:0007143]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic DNA integrity checkpoint [GO:0044774]; negative regulation of DNA duplex unwinding [GO:1905463]; positive regulation of apoptotic process [GO:0043065]; positive regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; resolution of meiotic recombination intermediates [GO:0000712]; rhythmic process [GO:0048511]; sister chromatid segregation [GO:0000819]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	apoptotic chromosome condensation [GO:0030263]; cellular response to DNA damage stimulus [GO:0006974]; chromosome segregation [GO:0007059]; DNA ligation [GO:0006266]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; female meiotic nuclear division [GO:0007143]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic DNA integrity checkpoint [GO:0044774]; negative regulation of DNA duplex unwinding [GO:1905463]; positive regulation of apoptotic process [GO:0043065]; positive regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; resolution of meiotic recombination intermediates [GO:0000712]; rhythmic process [GO:0048511]; sister chromatid segregation [GO:0000819]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; viral integration complex [GO:0019035]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; DNA-dependent ATPase activity [GO:0008094]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; magnesium ion binding [GO:0000287]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]
d2wida__d3dcna1__1	Metazoa	Fungi	Chordata	Ascomycota	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]; pathogenesis [GO:0009405]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	pathogenesis [GO:0009405]	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	extracellular region [GO:0005576]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]	cutinase activity [GO:0050525]
d2wida__d5a7fa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d2wifa__d1sfrb___1	Metazoa		Chordata	Actinobacteria	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; growth of symbiont in host cell [GO:0044119]; growth of symbiont in host vacuole [GO:0044121]; mycolate cell wall layer assembly [GO:0071769]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	growth of symbiont in host cell [GO:0044119]; growth of symbiont in host vacuole [GO:0044121]; mycolate cell wall layer assembly [GO:0071769]	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]	diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]
d2wihb1_d3ddpb2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2wihd1_d1vola1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d2wija__d3puia1__1	Metazoa		Chordata	Actinobacteria	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	cocaine catabolic process [GO:0050784]	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	cytoplasm [GO:0005737]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]
d2wj2a__d3qj9b___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]	fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]	fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]	acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]	acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]
d2wjua1_d5a4ub1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	glutathione transferase activity [GO:0004364]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d2wjuc1_d2pgta2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2wjuc1_d3sbci___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]; identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]; cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]	glutathione transferase activity [GO:0004364]	identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]
d2wjuc2_d4zbbb2__1	Metazoa	Fungi	Chordata	Basidiomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione transferase activity [GO:0004364]	
d2wjud1_d4gwra___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; plasma membrane [GO:0005886]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; IRE1-mediated unfolded protein response [GO:0036498]; post-translational protein modification [GO:0043687]; protein folding [GO:0006457]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular protein metabolic process [GO:0044267]; IRE1-mediated unfolded protein response [GO:0036498]; post-translational protein modification [GO:0043687]; protein folding [GO:0006457]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; plasma membrane [GO:0005886]	glutathione transferase activity [GO:0004364]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide isomerase activity [GO:0003756]
d2wjud2_d1aqva1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2wjue2_d4ivfb2__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione transferase activity [GO:0004364]	
d2wjuf1_d4hu7b___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutathione transferase activity [GO:0004364]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2wjuf2_d4ofma2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d2wk5c1_d2elcc1__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]		growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]
d2wk5d3_d1otpa3__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	cytosol [GO:0005829]; membrane [GO:0016020]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	cellular response to DNA damage stimulus [GO:0006974]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; thymidine metabolic process [GO:0046104]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]	growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d2wk6a3_d1brwb3__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	cytosol [GO:0005829]		growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]	metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d2wk6a3_d5ep8b3__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleoside salvage [GO:0043097]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969]	pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	cytosol [GO:0005829]	cytosol [GO:0005829]	growth factor activity [GO:0008083]; phosphorylase activity [GO:0004645]; protein homodimerization activity [GO:0042803]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]	metal ion binding [GO:0046872]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d2wkkd__d3w59c___1	Fungi	Metazoa	Basidiomycota	Chordata	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	cell wall [GO:0005618]; endomembrane system [GO:0012505]; extracellular region [GO:0005576]; membrane [GO:0016020]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d2wkma__d4bbea___1	Metazoa	Metazoa	Chordata	Chordata	basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; hepatocyte growth factor-activated receptor activity [GO:0005008]; identical protein binding [GO:0042802]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; semaphorin receptor activity [GO:0017154]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; branching morphogenesis of an epithelial tube [GO:0048754]; cell surface receptor signaling pathway [GO:0007166]; endothelial cell morphogenesis [GO:0001886]; entry of bacterium into host cell [GO:0035635]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of autophagy [GO:0010507]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	caveola [GO:0005901]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome lumen [GO:0031904]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; acetylcholine receptor binding [GO:0033130]; ATP binding [GO:0005524]; growth hormone receptor binding [GO:0005131]; heme binding [GO:0020037]; histone binding [GO:0042393]; histone kinase activity (H3-Y41 specific) [GO:0035401]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; interleukin-12 receptor binding [GO:0005143]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; type 1 angiotensin receptor binding [GO:0031702]; actin filament polymerization [GO:0030041]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activation of Janus kinase activity [GO:0042976]; activation of MAPKK activity [GO:0000186]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; axon regeneration [GO:0031103]; blood coagulation [GO:0007596]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; enzyme linked receptor protein signaling pathway [GO:0007167]; erythrocyte differentiation [GO:0030218]; extrinsic apoptotic signaling pathway [GO:0097191]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; histone H3-Y41 phosphorylation [GO:0035409]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; mammary gland epithelium development [GO:0061180]; MAPK cascade [GO:0000165]; mesoderm development [GO:0007498]; microglial cell activation [GO:0001774]; mineralocorticoid receptor signaling pathway [GO:0031959]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of DNA binding [GO:0043392]; negative regulation of heart contraction [GO:0045822]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell activation [GO:0050867]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial cell apoptotic process [GO:1904037]; positive regulation of growth factor dependent skeletal muscle satellite cell proliferation [GO:1902728]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; positive regulation of inflammatory response [GO:0050729]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; postsynapse to nucleus signaling pathway [GO:0099527]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of inflammatory response [GO:0050727]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; response to antibiotic [GO:0046677]; response to hydroperoxide [GO:0033194]; response to interleukin-12 [GO:0070671]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; tyrosine phosphorylation of STAT protein [GO:0007260]	branching morphogenesis of an epithelial tube [GO:0048754]; cell surface receptor signaling pathway [GO:0007166]; endothelial cell morphogenesis [GO:0001886]; entry of bacterium into host cell [GO:0035635]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of autophagy [GO:0010507]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin filament polymerization [GO:0030041]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activation of Janus kinase activity [GO:0042976]; activation of MAPKK activity [GO:0000186]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; axon regeneration [GO:0031103]; blood coagulation [GO:0007596]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; enzyme linked receptor protein signaling pathway [GO:0007167]; erythrocyte differentiation [GO:0030218]; extrinsic apoptotic signaling pathway [GO:0097191]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; histone H3-Y41 phosphorylation [GO:0035409]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; mammary gland epithelium development [GO:0061180]; MAPK cascade [GO:0000165]; mesoderm development [GO:0007498]; microglial cell activation [GO:0001774]; mineralocorticoid receptor signaling pathway [GO:0031959]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of heart contraction [GO:0045822]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell activation [GO:0050867]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial cell apoptotic process [GO:1904037]; positive regulation of growth factor dependent skeletal muscle satellite cell proliferation [GO:1902728]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; positive regulation of inflammatory response [GO:0050729]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; postsynapse to nucleus signaling pathway [GO:0099527]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of inflammatory response [GO:0050727]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; response to antibiotic [GO:0046677]; response to hydroperoxide [GO:0033194]; response to interleukin-12 [GO:0070671]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; tyrosine phosphorylation of STAT protein [GO:0007260]	basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	caveola [GO:0005901]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome lumen [GO:0031904]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	ATP binding [GO:0005524]; hepatocyte growth factor-activated receptor activity [GO:0005008]; identical protein binding [GO:0042802]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; semaphorin receptor activity [GO:0017154]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	acetylcholine receptor binding [GO:0033130]; ATP binding [GO:0005524]; growth hormone receptor binding [GO:0005131]; heme binding [GO:0020037]; histone binding [GO:0042393]; histone kinase activity (H3-Y41 specific) [GO:0035401]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; interleukin-12 receptor binding [GO:0005143]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; type 1 angiotensin receptor binding [GO:0031702]
d2wksa__d5yhme___1			Proteobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d2wkse__d1gqod___1			Proteobacteria	Firmicutes	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d2wksf__d1uqra___1			Proteobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d2wktc2_d5bnma2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2wktc2_d5byvg2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2wktd2_d5bnsb2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2wkua1_d2vtzd2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2wkua2_d2byzc2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2wkua2_d2wl6c1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2wkuc2_d1m3kb1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2wkuc2_d2c9ha2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2wkud1_d1m1od2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2wkud2_d2vb8d2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2wkva1_d3a5sb2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]; protein-chromophore linkage [GO:0018298]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	flavonoid biosynthetic process [GO:0009813]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2wkvb1_d1fj8b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2wkvc2_d4ubud2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d2wkvd2_d1x9ea2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d2wkwa__d5uy1b1__1			Proteobacteria	Actinobacteria		haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]		response to toxic substance [GO:0009636]				haloalkane dehalogenase activity [GO:0018786]
d2wkwb__d1mx9a___1		Metazoa	Proteobacteria	Chordata		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]		carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d2wkyb__d1fcka1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d2wkza__d5p3qa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2wkzb__d4ckub___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2wl0a__d5p44a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2wl0b__d4rvja___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2wl1a__d3lgra1__1	Metazoa	Fungi	Chordata	Ascomycota	autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; actin binding [GO:0003779]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; inflammatory response [GO:0006954]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; positive regulation of autophagy [GO:0010508]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; response to interferon-gamma [GO:0034341]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	inflammatory response [GO:0006954]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; positive regulation of autophagy [GO:0010508]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; response to interferon-gamma [GO:0034341]	xylan catabolic process [GO:0045493]	autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	extracellular region [GO:0005576]	actin binding [GO:0003779]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	endo-1,4-beta-xylanase activity [GO:0031176]
d2wl4c1_d5lp7c2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; acetyl-CoA C-acyltransferase activity [GO:0003988]; fatty acid beta-oxidation [GO:0006635]; sporulation resulting in formation of a cellular spore [GO:0030435]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid beta-oxidation [GO:0006635]; sporulation resulting in formation of a cellular spore [GO:0030435]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	acetyl-CoA C-acetyltransferase activity [GO:0003985]; acetyl-CoA C-acyltransferase activity [GO:0003988]
d2wl5c1_d1og8b3__1			Proteobacteria		cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]		poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	
d2wl5d1_d3v4xb2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d2wl5d2_d4v2pa2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2wl6a1_d2cdhd2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetyl-CoA C-acetyltransferase activity [GO:0003985]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2wl9a2_d3ojtc1__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]				dioxygenase activity [GO:0051213]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d2wl9d1_d2ei2a1__1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	1,2-dihydroxynaphthalene dioxygenase activity [GO:0018554]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; naphthalene catabolic process [GO:1901170]	aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	naphthalene catabolic process [GO:1901170]			dioxygenase activity [GO:0051213]; ferrous iron binding [GO:0008198]	1,2-dihydroxynaphthalene dioxygenase activity [GO:0018554]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d2wlja2_d1urze1__1			Proteobacteria		integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; regulation of ion transmembrane transport [GO:0034765]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	regulation of ion transmembrane transport [GO:0034765]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2wlka2_d2wlia2__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; regulation of ion transmembrane transport [GO:0034765]	integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; regulation of ion transmembrane transport [GO:0034765]	regulation of ion transmembrane transport [GO:0034765]	regulation of ion transmembrane transport [GO:0034765]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]	identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]
d2wlkb2_d1nm4a___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; regulation of ion transmembrane transport [GO:0034765]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	regulation of ion transmembrane transport [GO:0034765]	copper ion transport [GO:0006825]; response to copper ion [GO:0046688]	integral component of membrane [GO:0016021]	periplasmic space [GO:0042597]	identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]	copper ion binding [GO:0005507]
d2wm1a__d2qeec2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminocarboxymuconate-semialdehyde decarboxylase activity [GO:0001760]; hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]; negative regulation of quinolinate biosynthetic process [GO:1904985]; picolinic acid biosynthetic process [GO:1905004]; regulation of 'de novo' NAD biosynthetic process from tryptophan [GO:1905012]; tryptophan catabolic process [GO:0006569]	metal ion binding [GO:0046872]	negative regulation of quinolinate biosynthetic process [GO:1904985]; picolinic acid biosynthetic process [GO:1905004]; regulation of 'de novo' NAD biosynthetic process from tryptophan [GO:1905012]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		aminocarboxymuconate-semialdehyde decarboxylase activity [GO:0001760]; hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d2wm4a__d4l4ca___1			Actinobacteria	Proteobacteria	cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; cholesterol 26-hydroxylase activity [GO:0031073]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; NADPH binding [GO:0070402]; fatty acid omega-oxidation [GO:0010430]; methyl-branched fatty acid metabolic process [GO:0097089]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	fatty acid omega-oxidation [GO:0010430]; methyl-branched fatty acid metabolic process [GO:0097089]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; cholesterol 26-hydroxylase activity [GO:0031073]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; NADPH binding [GO:0070402]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2wm8a1_d4hgqb___1	Metazoa		Chordata	Bacteroidetes	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]			acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d2wmeb__d1o04a___1		Metazoa	Proteobacteria	Chordata	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glycine betaine biosynthetic process from choline [GO:0019285]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2wmed__d4h80d___1		Metazoa	Proteobacteria	Chordata	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	glycine betaine biosynthetic process from choline [GO:0019285]	aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]
d2wmef__d4kwgg___1		Metazoa	Proteobacteria	Chordata	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glycine betaine biosynthetic process from choline [GO:0019285]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d2wmia2_d2wmfa2__1				Firmicutes		metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				metal ion binding [GO:0046872]
d2wmyb__d2p4uc___1		Metazoa	Proteobacteria	Chordata	protein tyrosine phosphatase activity [GO:0004725]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; sarcolemma [GO:0042383]; acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]				cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; sarcolemma [GO:0042383]	protein tyrosine phosphatase activity [GO:0004725]	acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]
d2wmyc__d1c0ea___1		Metazoa	Proteobacteria	Chordata	protein tyrosine phosphatase activity [GO:0004725]	cytoplasm [GO:0005737]; acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]				cytoplasm [GO:0005737]	protein tyrosine phosphatase activity [GO:0004725]	acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]
d2wmyd__d1u2qa___1			Proteobacteria	Actinobacteria	protein tyrosine phosphatase activity [GO:0004725]	extracellular region [GO:0005576]; host cell endosome [GO:0044174]; plasma membrane [GO:0005886]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein dephosphorylation [GO:0006470]		negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein dephosphorylation [GO:0006470]		extracellular region [GO:0005576]; host cell endosome [GO:0044174]; plasma membrane [GO:0005886]	protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d2wmye__d4etma1__1			Proteobacteria	Firmicutes	protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]					protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d2wmyf__d3n8ia___1		Metazoa	Proteobacteria	Chordata	protein tyrosine phosphatase activity [GO:0004725]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; extracellular exosome [GO:0070062]; acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]				cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; extracellular exosome [GO:0070062]	protein tyrosine phosphatase activity [GO:0004725]	acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]
d2wmyg__d1z12a___1		Metazoa	Proteobacteria	Chordata	protein tyrosine phosphatase activity [GO:0004725]	cytoplasm [GO:0005737]; acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]				cytoplasm [GO:0005737]	protein tyrosine phosphatase activity [GO:0004725]	acid phosphatase activity [GO:0003993]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein tyrosine phosphatase activity [GO:0004725]
d2wn0b__d3hw7a___1		Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]		activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]		chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d2wn4a2_d2c8db___1			Firmicutes		extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]	transferase activity, transferring pentosyl groups [GO:0016763]
d2wn6a2_d1r45a___1			Firmicutes		extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]	transferase activity, transferring pentosyl groups [GO:0016763]
d2wn9a1_d2ymeh___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2wncd1_d4zk1h1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2wnce1_d2xytg___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2wnda__d1lvcd___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d2wnha1_d2enwa___1			Proteobacteria	Deinococcus-Thermus	3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]					3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]
d2wnja1_d3u8le___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2wnla1_d5ouid___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d2wnle1_d1uw6l___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2wnpf__d1re4f1__1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]; cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular region [GO:0005576]; extrinsic component of external side of plasma membrane [GO:0031232]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	carbohydrate binding [GO:0030246]; G protein-coupled receptor binding [GO:0001664]; metal ion binding [GO:0046872]; sialic acid binding [GO:0033691]; signaling pattern recognition receptor activity [GO:0008329]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]
d2wnqa1_d4xz9b___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d2wnqc1_d1yxdb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]
d2wnrc1_d1efga3__1			Euryarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	RNA catabolic process [GO:0006401]		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasm [GO:0005737]	3'-5'-exoribonuclease activity [GO:0000175]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2wnrc2_d2br2q2__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]	rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]	3'-5'-exoribonuclease activity [GO:0000175]
d2wnrf2_d4ba2b2__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	RNA catabolic process [GO:0006401]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d2wnsb1_d1qk3b1__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; identical protein binding [GO:0042802]; orotate phosphoribosyltransferase activity [GO:0004588]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular response to drug [GO:0035690]; female pregnancy [GO:0007565]; lactation [GO:0007595]; pyrimidine nucleobase biosynthetic process [GO:0019856]; pyrimidine nucleoside biosynthetic process [GO:0046134]; UMP biosynthetic process [GO:0006222]	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; xanthine phosphoribosyltransferase activity [GO:0000310]; GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular response to drug [GO:0035690]; female pregnancy [GO:0007565]; lactation [GO:0007595]; pyrimidine nucleobase biosynthetic process [GO:0019856]; pyrimidine nucleoside biosynthetic process [GO:0046134]; UMP biosynthetic process [GO:0006222]	GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; orotate phosphoribosyltransferase activity [GO:0004588]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; xanthine phosphoribosyltransferase activity [GO:0000310]
d2wnxa1_d5gxxb2__1			Firmicutes	Firmicutes	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2wo2a1_d2wyfe___1	Metazoa		Chordata	Proteobacteria	focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; ephrin receptor binding [GO:0046875]; virus receptor activity [GO:0001618]; anatomical structure morphogenesis [GO:0009653]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; ephrin receptor signaling pathway [GO:0048013]; lymph vessel development [GO:0001945]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of neuron projection development [GO:0010977]; nephric duct morphogenesis [GO:0072178]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of neuron death [GO:1901216]; presynapse assembly [GO:0099054]; regulation of chemotaxis [GO:0050920]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; T cell costimulation [GO:0031295]; venous blood vessel morphogenesis [GO:0048845]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	anatomical structure morphogenesis [GO:0009653]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; ephrin receptor signaling pathway [GO:0048013]; lymph vessel development [GO:0001945]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of neuron projection development [GO:0010977]; nephric duct morphogenesis [GO:0072178]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of neuron death [GO:1901216]; presynapse assembly [GO:0099054]; regulation of chemotaxis [GO:0050920]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; T cell costimulation [GO:0031295]; venous blood vessel morphogenesis [GO:0048845]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	ephrin receptor binding [GO:0046875]; virus receptor activity [GO:0001618]	carbohydrate binding [GO:0030246]
d2wo3a1_d4omca2__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; axon [GO:0030424]; axon terminus [GO:0043679]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; mitochondrial outer membrane [GO:0005741]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; DH domain binding [GO:0097161]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; PH domain binding [GO:0042731]; protein kinase activity [GO:0004672]; protein tyrosine kinase binding [GO:1990782]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to amyloid-beta [GO:1904646]; cochlea development [GO:0090102]; corticospinal tract morphogenesis [GO:0021957]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; negative regulation of axon regeneration [GO:0048681]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron projection development [GO:0010977]; negative regulation of proteolysis involved in cellular protein catabolic process [GO:1903051]; nephric duct morphogenesis [GO:0072178]; neuron projection fasciculation [GO:0106030]; neuron projection guidance [GO:0097485]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of astrocyte differentiation [GO:0048710]; regulation of axonogenesis [GO:0050770]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of modification of synaptic structure [GO:1905244]; synapse pruning [GO:0098883]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to amyloid-beta [GO:1904646]; cochlea development [GO:0090102]; corticospinal tract morphogenesis [GO:0021957]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; negative regulation of axon regeneration [GO:0048681]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron projection development [GO:0010977]; negative regulation of proteolysis involved in cellular protein catabolic process [GO:1903051]; nephric duct morphogenesis [GO:0072178]; neuron projection fasciculation [GO:0106030]; neuron projection guidance [GO:0097485]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of astrocyte differentiation [GO:0048710]; regulation of axonogenesis [GO:0050770]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of modification of synaptic structure [GO:1905244]; synapse pruning [GO:0098883]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	adherens junction [GO:0005912]; axon [GO:0030424]; axonal growth cone [GO:0044295]; axon terminus [GO:0043679]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; mitochondrial outer membrane [GO:0005741]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; DH domain binding [GO:0097161]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; PH domain binding [GO:0042731]; protein kinase activity [GO:0004672]; protein tyrosine kinase binding [GO:1990782]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d2wo3b__d1aoza3__1	Metazoa	Viridiplantae	Chordata	Streptophyta	adherens junction [GO:0005912]; axon [GO:0030424]; axon terminus [GO:0043679]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; mitochondrial outer membrane [GO:0005741]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; DH domain binding [GO:0097161]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; PH domain binding [GO:0042731]; protein kinase activity [GO:0004672]; protein tyrosine kinase binding [GO:1990782]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to amyloid-beta [GO:1904646]; cochlea development [GO:0090102]; corticospinal tract morphogenesis [GO:0021957]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; negative regulation of axon regeneration [GO:0048681]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron projection development [GO:0010977]; negative regulation of proteolysis involved in cellular protein catabolic process [GO:1903051]; nephric duct morphogenesis [GO:0072178]; neuron projection fasciculation [GO:0106030]; neuron projection guidance [GO:0097485]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of astrocyte differentiation [GO:0048710]; regulation of axonogenesis [GO:0050770]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of modification of synaptic structure [GO:1905244]; synapse pruning [GO:0098883]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to amyloid-beta [GO:1904646]; cochlea development [GO:0090102]; corticospinal tract morphogenesis [GO:0021957]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; negative regulation of axon regeneration [GO:0048681]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron projection development [GO:0010977]; negative regulation of proteolysis involved in cellular protein catabolic process [GO:1903051]; nephric duct morphogenesis [GO:0072178]; neuron projection fasciculation [GO:0106030]; neuron projection guidance [GO:0097485]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of astrocyte differentiation [GO:0048710]; regulation of axonogenesis [GO:0050770]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of modification of synaptic structure [GO:1905244]; synapse pruning [GO:0098883]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adherens junction [GO:0005912]; axon [GO:0030424]; axonal growth cone [GO:0044295]; axon terminus [GO:0043679]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; mitochondrial outer membrane [GO:0005741]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]	extracellular region [GO:0005576]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; DH domain binding [GO:0097161]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; PH domain binding [GO:0042731]; protein kinase activity [GO:0004672]; protein tyrosine kinase binding [GO:1990782]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]
d2wo5a1_d2qjie___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; aromatic amino acid family biosynthetic process [GO:0009073]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	aromatic amino acid family biosynthetic process [GO:0009073]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]
d2wo9b__d4ilwf___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; proteolysis [GO:0006508]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d2wo9d__d5ldsd2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d2woaa__d1lnce___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d2woab__d1buvm___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; intermediate filament cytoskeleton [GO:0045111]; macropinosome [GO:0044354]; melanosome [GO:0042470]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; metalloaminopeptidase activity [GO:0070006]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; astrocyte cell migration [GO:0043615]; branching morphogenesis of an epithelial tube [GO:0048754]; cell motility [GO:0048870]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; endodermal cell differentiation [GO:0035987]; endothelial cell proliferation [GO:0001935]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; head development [GO:0060322]; lung development [GO:0030324]; male gonad development [GO:0008584]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle development [GO:0001541]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of macrophage migration [GO:1905523]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein processing [GO:0010954]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein localization to plasma membrane [GO:1903076]; response to estrogen [GO:0043627]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to odorant [GO:1990834]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; skeletal system development [GO:0001501]; tissue remodeling [GO:0048771]; zymogen activation [GO:0031638]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	angiogenesis [GO:0001525]; astrocyte cell migration [GO:0043615]; branching morphogenesis of an epithelial tube [GO:0048754]; cell motility [GO:0048870]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; endodermal cell differentiation [GO:0035987]; endothelial cell proliferation [GO:0001935]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; head development [GO:0060322]; lung development [GO:0030324]; male gonad development [GO:0008584]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle development [GO:0001541]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of macrophage migration [GO:1905523]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein processing [GO:0010954]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein localization to plasma membrane [GO:1903076]; response to estrogen [GO:0043627]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to odorant [GO:1990834]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; skeletal system development [GO:0001501]; tissue remodeling [GO:0048771]; zymogen activation [GO:0031638]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; intermediate filament cytoskeleton [GO:0045111]; macropinosome [GO:0044354]; melanosome [GO:0042470]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; metalloaminopeptidase activity [GO:0070006]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d2woac__d2ozrf___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d2woba1_d3zu8a1__1			Firmicutes	Firmicutes	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]			cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d2woeb__d1t5ja1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; ADP-ribosyl-[dinitrogen reductase] hydrolase activity [GO:0047407]; metal ion binding [GO:0046872]; nitrogen fixation [GO:0009399]; protein de-ADP-ribosylation [GO:0051725]	hydrolase activity [GO:0016787]	nitrogen fixation [GO:0009399]; protein de-ADP-ribosylation [GO:0051725]		cytoplasm [GO:0005737]		ADP-ribosyl-[dinitrogen reductase] hydrolase activity [GO:0047407]; metal ion binding [GO:0046872]	hydrolase activity [GO:0016787]
d2woqa__d1w5oa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]; heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]; heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]	cytosol [GO:0005829]	porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]	porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]
d2wora__d2q91a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d2wosa__d4pe0x___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d2wota1_d2c5oa___1	Metazoa	Metazoa	Chordata	Chordata	activin receptor complex [GO:0048179]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell surface [GO:0009986]; endosome [GO:0005768]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; activin binding [GO:0048185]; activin receptor activity, type I [GO:0016361]; ATP binding [GO:0005524]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity, type I [GO:0005025]; transforming growth factor beta-activated receptor activity [GO:0005024]; type II transforming growth factor beta receptor binding [GO:0005114]; activation of MAPKK activity [GO:0000186]; activin receptor signaling pathway [GO:0032924]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; epicardium morphogenesis [GO:1905223]; epithelial to mesenchymal transition [GO:0001837]; extracellular structure organization [GO:0043062]; germ cell migration [GO:0008354]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; protein deubiquitination [GO:0016579]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; regulation of transcription, DNA-templated [GO:0006355]; response to cholesterol [GO:0070723]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	activation of MAPKK activity [GO:0000186]; activin receptor signaling pathway [GO:0032924]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; epicardium morphogenesis [GO:1905223]; epithelial to mesenchymal transition [GO:0001837]; extracellular structure organization [GO:0043062]; germ cell migration [GO:0008354]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; protein deubiquitination [GO:0016579]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; regulation of transcription, DNA-templated [GO:0006355]; response to cholesterol [GO:0070723]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	activin receptor complex [GO:0048179]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell surface [GO:0009986]; endosome [GO:0005768]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	activin binding [GO:0048185]; activin receptor activity, type I [GO:0016361]; ATP binding [GO:0005524]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta-activated receptor activity [GO:0005024]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity, type I [GO:0005025]; type II transforming growth factor beta receptor binding [GO:0005114]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2woxc__d4i3uc___1			Proteobacteria	Proteobacteria	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	glycine betaine biosynthetic process from choline [GO:0019285]				aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d2woxd__d2euhc___1			Proteobacteria	Firmicutes	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	glycine betaine biosynthetic process from choline [GO:0019285]				aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]
d2woxd__d3rhqa___1		Metazoa	Proteobacteria	Chordata	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine betaine biosynthetic process from choline [GO:0019285]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]
d2wp3t__d3bqua1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2wp9b2_d1gt8c1__1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d2wp9b2_d3cirb1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d2wp9e3_d2b76m1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d2wp9f1_d1pfda___1		Viridiplantae	Proteobacteria	Streptophyta	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	chloroplast [GO:0009507]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	chloroplast [GO:0009507]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2wp9i2_d1e7pg3__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d2wpjs__d2qxia___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]	peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2wpua1_d2cama___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]; antibacterial humoral response [GO:0019731]		antibacterial humoral response [GO:0019731]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2wq6a1_d4mlpd1__1	Metazoa	Metazoa	Arthropoda	Chordata	nucleotide binding [GO:0000166]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; FAD binding [GO:0071949]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; phosphatase binding [GO:0019902]; photoreceptor activity [GO:0009881]; protein kinase binding [GO:0019901]; single-stranded DNA binding [GO:0003697]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; protein import into nucleus [GO:0006606]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]		circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-chromophore linkage [GO:0018298]; protein import into nucleus [GO:0006606]; regulation of circadian rhythm [GO:0042752]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleotide binding [GO:0000166]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; FAD binding [GO:0071949]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; phosphatase binding [GO:0019902]; photoreceptor activity [GO:0009881]; protein kinase binding [GO:0019901]; single-stranded DNA binding [GO:0003697]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2wq7a2_d1iqua1__1	Metazoa		Arthropoda	Deinococcus-Thermus	nucleotide binding [GO:0000166]	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]		DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]			nucleotide binding [GO:0000166]	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]
d2wq8a1_d4iuga4__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	extracellular space [GO:0005615]; beta-galactosidase activity [GO:0004565]; galactose binding [GO:0005534]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]		lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	beta-galactosidase activity [GO:0004565]; galactose binding [GO:0005534]
d2wq8a2_d5c86a1__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]				extracellular region [GO:0005576]		galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	
d2wqae__d1kzxa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cytosol [GO:0005829]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]
d2wqaf__d5xm5b___1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]; cadmium ion binding [GO:0046870]; zinc ion binding [GO:0008270]; cellular response to zinc ion starvation [GO:0034224]; response to cadmium ion [GO:0046686]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular response to zinc ion starvation [GO:0034224]; response to cadmium ion [GO:0046686]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	cadmium ion binding [GO:0046870]; zinc ion binding [GO:0008270]
d2wqka__d4xgba1__1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; 3'-nucleotidase activity [GO:0008254]; 5'-nucleotidase activity [GO:0008253]; exopolyphosphatase activity [GO:0004309]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UMP catabolic process [GO:0046050]	cytoplasm [GO:0005737]; 3'-nucleotidase activity [GO:0008254]; 5'-nucleotidase activity [GO:0008253]; exopolyphosphatase activity [GO:0004309]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UMP catabolic process [GO:0046050]	UMP catabolic process [GO:0046050]	UMP catabolic process [GO:0046050]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3'-nucleotidase activity [GO:0008254]; 5'-nucleotidase activity [GO:0008253]; exopolyphosphatase activity [GO:0004309]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3'-nucleotidase activity [GO:0008254]; 5'-nucleotidase activity [GO:0008253]; exopolyphosphatase activity [GO:0004309]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2wqlb__d1fskg___1	Viridiplantae	Metazoa	Streptophyta	Chordata	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2wqlb__d4n3ez___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]			abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2wqlc__d3ijtb1__1	Viridiplantae		Streptophyta	Firmicutes	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]				abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	
d2wqlc__d4bk6b___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2wqld__d2flhc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]			abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2wqra3_d3u6rl___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2wqrb3_d3stlb2__1	Metazoa		Chordata	Actinobacteria	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	voltage-gated potassium channel complex [GO:0008076]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d2wqtf__d5d2ka___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]		cytoplasm [GO:0005737]		2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d2wqto__d5d2kb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]		cytoplasm [GO:0005737]		2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d2wqtq__d2eb6c___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	2-hydroxyhexa-2,4-dienoate hydratase activity [GO:0034856]; 2-oxo-hept-3-ene-1,7-dioate hydratase activity [GO:0018817]; 2-oxopent-4-enoate hydratase activity [GO:0008684]; 4-oxalocrotonate decarboxylase activity [GO:0047437]; metal ion binding [GO:0046872]; aromatic compound catabolic process [GO:0019439]	3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]		2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]	2-hydroxyhexa-2,4-dienoate hydratase activity [GO:0034856]; 2-oxo-hept-3-ene-1,7-dioate hydratase activity [GO:0018817]; 2-oxopent-4-enoate hydratase activity [GO:0008684]; 4-oxalocrotonate decarboxylase activity [GO:0047437]; metal ion binding [GO:0046872]
d2wqts__d1qqja2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; 2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]; arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]	arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	cytoplasm [GO:0005737]		2-oxopent-4-enoate hydratase activity [GO:0008684]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]	fumarylacetoacetase activity [GO:0004334]; metal ion binding [GO:0046872]
d2wqua1_d2omya2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	pathogenesis [GO:0009405]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	heparin binding [GO:0008201]; lipid binding [GO:0008289]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2wqua1_d2r9uc1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		heparin binding [GO:0008201]; lipid binding [GO:0008289]	
d2wque1_d2ifga3__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	pathogenesis [GO:0009405]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]	heparin binding [GO:0008201]; lipid binding [GO:0008289]	cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]
d2wque2_d2a9db2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	pathogenesis [GO:0009405]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	heparin binding [GO:0008201]; lipid binding [GO:0008289]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]
d2wquf1_d1m0zb___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; thrombin-activated receptor activity [GO:0015057]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	pathogenesis [GO:0009405]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	heparin binding [GO:0008201]; lipid binding [GO:0008289]	thrombin-activated receptor activity [GO:0015057]
d2wqwa1_d2hr7b3__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	axon [GO:0030424]; caveola [GO:0005901]; dendrite membrane [GO:0032590]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; insulin receptor complex [GO:0005899]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; cargo receptor activity [GO:0038024]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; insulin binding [GO:0043559]; insulin receptor substrate binding [GO:0043560]; insulin-activated receptor activity [GO:0005009]; insulin-like growth factor I binding [GO:0031994]; insulin-like growth factor II binding [GO:0031995]; insulin-like growth factor receptor binding [GO:0005159]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; PTB domain binding [GO:0051425]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of MAPK activity [GO:0000187]; activation of protein kinase activity [GO:0032147]; activation of protein kinase B activity [GO:0032148]; adrenal gland development [GO:0030325]; amyloid-beta clearance [GO:0097242]; anatomical structure development [GO:0048856]; carbohydrate metabolic process [GO:0005975]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; dendritic spine maintenance [GO:0097062]; epidermis development [GO:0008544]; exocrine pancreas development [GO:0031017]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose homeostasis [GO:0042593]; heart morphogenesis [GO:0003007]; insulin receptor signaling pathway [GO:0008286]; learning [GO:0007612]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; memory [GO:0007613]; neuron projection maintenance [GO:1990535]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of developmental growth [GO:0048639]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of meiotic cell cycle [GO:0051446]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of respiratory burst [GO:0060267]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein heterotetramerization [GO:0051290]; protein phosphorylation [GO:0006468]; receptor-mediated endocytosis [GO:0006898]; regulation of embryonic development [GO:0045995]; regulation of female gonad development [GO:2000194]; regulation of transcription, DNA-templated [GO:0006355]; transformation of host cell by virus [GO:0019087]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	pathogenesis [GO:0009405]	activation of MAPK activity [GO:0000187]; activation of protein kinase activity [GO:0032147]; activation of protein kinase B activity [GO:0032148]; adrenal gland development [GO:0030325]; amyloid-beta clearance [GO:0097242]; anatomical structure development [GO:0048856]; carbohydrate metabolic process [GO:0005975]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; dendritic spine maintenance [GO:0097062]; epidermis development [GO:0008544]; exocrine pancreas development [GO:0031017]; glucose homeostasis [GO:0042593]; G protein-coupled receptor signaling pathway [GO:0007186]; heart morphogenesis [GO:0003007]; insulin receptor signaling pathway [GO:0008286]; learning [GO:0007612]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; memory [GO:0007613]; neuron projection maintenance [GO:1990535]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of developmental growth [GO:0048639]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of meiotic cell cycle [GO:0051446]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of respiratory burst [GO:0060267]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein heterotetramerization [GO:0051290]; protein phosphorylation [GO:0006468]; receptor-mediated endocytosis [GO:0006898]; regulation of embryonic development [GO:0045995]; regulation of female gonad development [GO:2000194]; regulation of transcription, DNA-templated [GO:0006355]; transformation of host cell by virus [GO:0019087]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	axon [GO:0030424]; caveola [GO:0005901]; dendrite membrane [GO:0032590]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; insulin receptor complex [GO:0005899]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	heparin binding [GO:0008201]; lipid binding [GO:0008289]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; cargo receptor activity [GO:0038024]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; insulin-activated receptor activity [GO:0005009]; insulin binding [GO:0043559]; insulin-like growth factor I binding [GO:0031994]; insulin-like growth factor II binding [GO:0031995]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor substrate binding [GO:0043560]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein tyrosine kinase activity [GO:0004713]; PTB domain binding [GO:0051425]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d2wqxa1_d1moxb1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	pathogenesis [GO:0009405]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	heparin binding [GO:0008201]; lipid binding [GO:0008289]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2wqxb2_d5kvfe___1			Firmicutes		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	pathogenesis [GO:0009405]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	heparin binding [GO:0008201]; lipid binding [GO:0008289]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2wqyb2_d1gt8a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d2wqyb2_d1kf6b1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d2wqyo1_d3b2fb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; electron transport chain [GO:0022900]; response to light stimulus [GO:0009416]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; response to light stimulus [GO:0009416]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2wr0a1_d4dj7a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; sialate O-acetylesterase activity [GO:0001681]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]; sialate O-acetylesterase activity [GO:0001681]	host cell surface receptor binding [GO:0046789]
d2wr0b1_d4zcje1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; sialate O-acetylesterase activity [GO:0001681]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]; sialate O-acetylesterase activity [GO:0001681]	host cell surface receptor binding [GO:0046789]
d2wr6a__d3jsqa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; protein heterodimerization activity [GO:0046982]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]; cardiac muscle tissue development [GO:0048738]; embryonic organ morphogenesis [GO:0048562]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; female genitalia morphogenesis [GO:0048807]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; lung development [GO:0030324]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; urinary bladder development [GO:0060157]; uterus development [GO:0060065]; vagina development [GO:0060068]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	cardiac muscle tissue development [GO:0048738]; embryonic organ morphogenesis [GO:0048562]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; female genitalia morphogenesis [GO:0048807]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; lung development [GO:0030324]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; urinary bladder development [GO:0060157]; uterus development [GO:0060065]; vagina development [GO:0060068]; visual perception [GO:0007601]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protein heterodimerization activity [GO:0046982]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d2wr9d__d2xr4a1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]					metal ion binding [GO:0046872]	identical protein binding [GO:0042802]
d2wrba1_d4lkja___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrba1_d5a3ie1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d2wrbb1_d4wsuc1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrbc1_d5bqye___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrcc1_d5hu8a1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrdb1_d4uo5a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wreb1_d4uo7c___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrec1_d2wrca1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrfa1_d4kdqc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrfb1_d3al4e___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrfd1_d4cqve1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrfd1_d4wsxg___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrfe1_d4cyva___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrfg1_d4jtvc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrfi1_d4cr0a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrgh__d4yyaa___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrhh__d4wsve1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2wrta2_d3zmkd2__1	Metazoa	Metazoa	Platyhelminthes	Arthropoda	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]			cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d2wrta2_d5gzzd2__1	Metazoa	Metazoa	Platyhelminthes	Platyhelminthes	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]			cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2wrtb1_d1ljra2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]		glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d2wrtb2_d4zbbb2__1	Metazoa	Fungi	Platyhelminthes	Basidiomycota	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]				cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]	
d2wrtd2_d2cvdb1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	glutathione transferase activity [GO:0004364]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d2wrte1_d4grfa1__1	Metazoa		Platyhelminthes	Bacteroidetes	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]	cell [GO:0005623]	glutathione transferase activity [GO:0004364]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]
d2wrtf1_d5e4wa1__1	Metazoa	Viridiplantae	Platyhelminthes	Streptophyta	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	chloroplast [GO:0009507]; chloroplast thylakoid [GO:0009534]; chloroplast thylakoid membrane [GO:0009535]; integral component of membrane [GO:0016021]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; membrane insertase activity [GO:0032977]; protein domain specific binding [GO:0019904]; protein heterotrimerization [GO:0070208]; protein import into chloroplast thylakoid membrane [GO:0045038]; protein insertion into membrane [GO:0051205]; protein localization to chloroplast [GO:0072598]; regulation of cell aging [GO:0090342]; thylakoid membrane organization [GO:0010027]		protein heterotrimerization [GO:0070208]; protein import into chloroplast thylakoid membrane [GO:0045038]; protein insertion into membrane [GO:0051205]; protein localization to chloroplast [GO:0072598]; regulation of cell aging [GO:0090342]; thylakoid membrane organization [GO:0010027]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]; chloroplast thylakoid [GO:0009534]; chloroplast thylakoid membrane [GO:0009535]; integral component of membrane [GO:0016021]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	glutathione transferase activity [GO:0004364]	identical protein binding [GO:0042802]; membrane insertase activity [GO:0032977]; protein domain specific binding [GO:0019904]
d2wrtg1_d1y25a1__1	Metazoa		Platyhelminthes	Actinobacteria	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; disulfide oxidoreductase activity [GO:0015036]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; oxidation-reduction process [GO:0055114]; pathogenesis [GO:0009405]; response to nitrosative stress [GO:0051409]; response to oxidative stress [GO:0006979]		cell redox homeostasis [GO:0045454]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; oxidation-reduction process [GO:0055114]; pathogenesis [GO:0009405]; response to nitrosative stress [GO:0051409]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	cell [GO:0005623]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]	glutathione transferase activity [GO:0004364]	disulfide oxidoreductase activity [GO:0015036]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]
d2wrth1_d3dgqb1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2wrti1_d2yanb1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; [2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]		[2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]	cytoplasm [GO:0005737]	cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]	glutathione transferase activity [GO:0004364]	electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]
d2wrti2_d1aqwa1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2wrtj1_d1md3b2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d2wrtl2_d3o3ta2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]		chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]
d2ws2a1_d1jzda1__1	Metazoa		Nematoda (roundworms)	Proteobacteria	transferase activity [GO:0016740]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	transferase activity [GO:0016740]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d2ws2a1_d3vwxb1__1	Metazoa	Metazoa	Nematoda (roundworms)	Arthropoda	transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]					transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]
d2ws2b1_d2fa4a___1	Metazoa	Fungi	Nematoda (roundworms)	Ascomycota	transferase activity [GO:0016740]	cell [GO:0005623]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; glutathione metabolic process [GO:0006749]; glycerol ether metabolic process [GO:0006662]; protein deglutathionylation [GO:0080058]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; sulfate assimilation [GO:0000103]; vacuole fusion, non-autophagic [GO:0042144]; vacuole inheritance [GO:0000011]		cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; glutathione metabolic process [GO:0006749]; glycerol ether metabolic process [GO:0006662]; protein deglutathionylation [GO:0080058]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; sulfate assimilation [GO:0000103]; vacuole fusion, non-autophagic [GO:0042144]; vacuole inheritance [GO:0000011]		cell [GO:0005623]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	transferase activity [GO:0016740]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]
d2ws2b2_d2vcvj2__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	transferase activity [GO:0016740]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]
d2wsjb__d5h9aa1__1		Metazoa	Firmicutes	Chordata	carboxy-lyase activity [GO:0016831]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; lipid homeostasis [GO:0055088]; retinoic acid biosynthetic process [GO:0002138]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]		lipid homeostasis [GO:0055088]; retinoic acid biosynthetic process [GO:0002138]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]		cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]	carboxy-lyase activity [GO:0016831]	all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]
d2wspa2_d1g1ya2__1			Thermotogae	Firmicutes	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	lysosome [GO:0005764]		alpha-L-fucosidase activity [GO:0004560]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2wsqa__d4y90c___1				Deinococcus-Thermus	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytosol [GO:0005829]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2wsqd__d3ta6a___1				Actinobacteria	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2wsra__d1ci1b___1					cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2wt3a1_d2vzub3__1				Actinobacteria		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2wt3a3_d3abzb4__1		Fungi		Ascomycota		beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]				beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d2wt9a__d3r77b___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; nicotinamidase activity [GO:0008936]	isochorismatase activity [GO:0008908]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]		pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]			metal ion binding [GO:0046872]; nicotinamidase activity [GO:0008936]	isochorismatase activity [GO:0008908]
d2wtfa2_d2asja1__1	Fungi		Ascomycota	Crenarchaeota	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d2wtfb2_d2imwp1__1	Fungi		Ascomycota	Crenarchaeota	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d2wtga__d3ubcd___1	Metazoa		Nematoda (roundworms)	Verrucomicrobia	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2wthb__d1m6mb___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2wu0b1_d3nfyb___1		Metazoa	Proteobacteria	Chordata	3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]
d2wu0c1_d2p6oa___1			Proteobacteria	Deinococcus-Thermus	3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]					3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]
d2wu0c1_d4odib___1			Proteobacteria	Apicomplexa	3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]	phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]			3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]	phosphoglycerate mutase activity [GO:0004619]
d2wu0d1_d3nfya___1		Metazoa	Proteobacteria	Chordata	3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	3-phytase activity [GO:0016158]; metal ion binding [GO:0046872]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]
d2wu2b1_d3ah7a1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d2wu2f2_d2fbwo2__1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d2wu2i2_d1knpa3__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; flavin adenine dinucleotide binding [GO:0050660]; L-aspartate oxidase activity [GO:0008734]; L-aspartate:fumarate oxidoreductase activity [GO:0044318]; 'de novo' NAD biosynthetic process from aspartate [GO:0034628]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	'de novo' NAD biosynthetic process from aspartate [GO:0034628]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	cytosol [GO:0005829]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	flavin adenine dinucleotide binding [GO:0050660]; L-aspartate:fumarate oxidoreductase activity [GO:0044318]; L-aspartate oxidase activity [GO:0008734]
d2wu2j2_d4ysxf2__1		Metazoa	Proteobacteria	Nematoda (roundworms)	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d2wu5i2_d2bs3d3__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d2wu8a__d5lu6b___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; plasma membrane [GO:0005886]; glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]
d2wu9a2_d1u0wc2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]; acetyl-CoA C-acyltransferase activity [GO:0003988]; fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]		acetyl-CoA C-acyltransferase activity [GO:0003988]	naringenin-chalcone synthase activity [GO:0016210]
d2wu9a2_d4yufa2__1	Viridiplantae		Streptophyta	Proteobacteria	endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]; acetyl-CoA C-acyltransferase activity [GO:0003988]; fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]	fatty acid biosynthetic process [GO:0006633]	endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]		acetyl-CoA C-acyltransferase activity [GO:0003988]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2wu9b2_d4o9cb1__1	Viridiplantae		Streptophyta	Proteobacteria	endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]; acetyl-CoA C-acyltransferase activity [GO:0003988]; fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]	cytoplasm [GO:0005737]	acetyl-CoA C-acyltransferase activity [GO:0003988]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d2wuaa1_d5bnmb1__1	Viridiplantae		Streptophyta	Proteobacteria	acetyl-CoA C-acyltransferase activity [GO:0003988]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		cytosol [GO:0005829]	acetyl-CoA C-acyltransferase activity [GO:0003988]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d2wuaa2_d1u6ea2__1	Viridiplantae		Streptophyta	Actinobacteria	acetyl-CoA C-acyltransferase activity [GO:0003988]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		cytoplasm [GO:0005737]	acetyl-CoA C-acyltransferase activity [GO:0003988]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d2wuaa2_d2wgfa2__1	Viridiplantae		Streptophyta	Actinobacteria	acetyl-CoA C-acyltransferase activity [GO:0003988]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]		fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	acetyl-CoA C-acyltransferase activity [GO:0003988]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]
d2wuab2_d3ov3d1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	acetyl-CoA C-acyltransferase activity [GO:0003988]	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]		flavonoid biosynthetic process [GO:0009813]			acetyl-CoA C-acyltransferase activity [GO:0003988]	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d2wubq2_d1nd0d1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	metal ion binding [GO:0046872]	proteolysis [GO:0006508]		cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]		serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	metal ion binding [GO:0046872]
d2wucl2_d2jb6h2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	proteolysis [GO:0006508]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2wucl2_d3eyvl1__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]		proteolysis [GO:0006508]		cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]		serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	
d2wueb__d3m3da___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; plasma membrane [GO:0005886]; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]; aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]	acetylcholinesterase activity [GO:0003990]
d2wufa__d1jmko___1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; plasma membrane [GO:0005886]; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]; aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; hydrolase activity, acting on ester bonds [GO:0016788]; ligase activity [GO:0016874]; phosphopantetheine binding [GO:0031177]; amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; antibiotic biosynthetic process [GO:0017000]; secondary metabolite biosynthetic process [GO:0044550]; sporulation resulting in formation of a cellular spore [GO:0030435]	aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]	amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; antibiotic biosynthetic process [GO:0017000]; secondary metabolite biosynthetic process [GO:0044550]; sporulation resulting in formation of a cellular spore [GO:0030435]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]	hydrolase activity, acting on ester bonds [GO:0016788]; ligase activity [GO:0016874]; phosphopantetheine binding [GO:0031177]
d2wuga__d1bcr.1__1		Viridiplantae	Actinobacteria	Streptophyta	cell wall [GO:0005618]; plasma membrane [GO:0005886]; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]; aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]	serine-type carboxypeptidase activity [GO:0004185]; proteolysis involved in cellular protein catabolic process [GO:0051603]	aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]	proteolysis involved in cellular protein catabolic process [GO:0051603]	cell wall [GO:0005618]; plasma membrane [GO:0005886]		2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]	serine-type carboxypeptidase activity [GO:0004185]
d2wugb__d5lkra___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; plasma membrane [GO:0005886]; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]; aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]
d2wusa1_d5br9a1__1			Thermotogae	Proteobacteria	integral component of membrane [GO:0016021]; DNA binding [GO:0003677]	tRNA threonylcarbamoyladenosine modification [GO:0002949]		tRNA threonylcarbamoyladenosine modification [GO:0002949]	integral component of membrane [GO:0016021]		DNA binding [GO:0003677]	
d2wusb2_d4h5nb1__1		Metazoa	Thermotogae	Chordata	integral component of membrane [GO:0016021]; DNA binding [GO:0003677]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]		ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	integral component of membrane [GO:0016021]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	DNA binding [GO:0003677]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d2wuta1_d1kt4a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]; cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]; membrane organization [GO:0061024]	extracellular space [GO:0005615]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	membrane organization [GO:0061024]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]	extracellular space [GO:0005615]	cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]	retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]
d2wv5a__d1zsla___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d2wvaa2_d1po7a1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2wvaa3_d2ihva2__1			Proteobacteria	Actinobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]
d2wvaa3_d4feea1__1			Proteobacteria		magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]						magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	
d2wvae2_d1yc2e___1			Proteobacteria	Euryarchaeota	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]				cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d2wvae3_d6bd9b3__1		Fungi	Proteobacteria	Ascomycota	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2wvav1_d4gp9a3__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2wvav3_d1zpdf2__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2wvax3_d2v3wd3__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2wvay1_d4qela1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2wvaz3_d2ihvc1__1			Proteobacteria	Actinobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]
d2wvba2_d2pa3a3__1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	L-serine biosynthetic process [GO:0006564]	protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]
d2wvbb2_d3od2b2__1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; protein homotetramerization [GO:0051289]; response to nickel cation [GO:0010045]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	negative regulation of DNA-templated transcription, initiation [GO:2000143]; protein homotetramerization [GO:0051289]; response to nickel cation [GO:0010045]	protein-DNA complex [GO:0032993]	protein-DNA complex [GO:0032993]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2wveb2_d3c1mc3__1			Proteobacteria	Euryarchaeota	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	cytosol [GO:0005829]; aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]; homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]
d2wvfa2_d2f1fb2__1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	acetolactate synthase complex [GO:0005948]; cytosol [GO:0005829]; acetolactate synthase activity [GO:0003984]; acetolactate synthase regulator activity [GO:1990610]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	protein-DNA complex [GO:0032993]	acetolactate synthase complex [GO:0005948]; cytosol [GO:0005829]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	acetolactate synthase activity [GO:0003984]; acetolactate synthase regulator activity [GO:1990610]
d2wvfb2_d2p9ec3__1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	L-serine biosynthetic process [GO:0006564]	protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]
d2wvga1_d2vk1b3__1		Fungi	Proteobacteria	Ascomycota	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2wvga2_d2ihua1__1			Proteobacteria	Actinobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]
d2wvga2_d5oj7a1__1		Metazoa	Proteobacteria	Chordata	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	mitochondrial matrix [GO:0005759]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; zinc ion binding [GO:0008270]; protein ADP-ribosylation [GO:0006471]		protein ADP-ribosylation [GO:0006471]		mitochondrial matrix [GO:0005759]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; zinc ion binding [GO:0008270]
d2wvgb3_d4mq5a1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2wvge3_d2c3yb2__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]		electron transport chain [GO:0022900]		cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d2wvgf2_d5d6rb2__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; butanediol metabolic process [GO:0034077]		butanediol metabolic process [GO:0034077]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2wvhb1_d2bp7b1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]					magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]
d2wvhb3_d3f6ex3__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2wvhe1_d2ji7a2__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]		oxalate catabolic process [GO:0033611]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d2wvhe2_d2w93c2__1		Fungi	Proteobacteria	Ascomycota	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2wvhe2_d3fzna2__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2wvhv1_d4jufd1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d2wvhv3_d1ngsa1__1		Fungi	Proteobacteria	Ascomycota	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]		pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d2wvhx2_d1m2ka1__1			Proteobacteria	Euryarchaeota	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]				cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	NAD+ binding [GO:0070403]; NAD-dependent protein deacetylase activity [GO:0034979]; protein-malonyllysine demalonylase activity [GO:0036054]; protein-succinyllysine desuccinylase activity [GO:0036055]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d2wvhx2_d2w93d2__1		Fungi	Proteobacteria	Ascomycota	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d2wvhy1_d2ihua2__1			Proteobacteria	Actinobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]
d2wvhy1_d2r5na1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d2wvhz2_d1efpa2__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	electron transfer activity [GO:0009055]					magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	electron transfer activity [GO:0009055]
d2ww4b1_d2go4b2__1			Proteobacteria	Aquificae	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity [GO:0050515]; ATP binding [GO:0005524]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	lipid A biosynthetic process [GO:0009245]			4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity [GO:0050515]; ATP binding [GO:0005524]	metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d2wwea1_d1h6ha___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886]; 1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol phosphate kinase activity [GO:0016307]; chemotaxis [GO:0006935]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; viral RNA genome replication [GO:0039694]	cell [GO:0005623]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; membrane [GO:0016020]; NADPH oxidase complex [GO:0043020]; phagolysosome [GO:0032010]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3-phosphate binding [GO:0032266]; protein dimerization activity [GO:0046983]; superoxide-generating NADPH oxidase activator activity [GO:0016176]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; immune response [GO:0006955]; oxidation-reduction process [GO:0055114]; phagocytosis [GO:0006909]; respiratory burst [GO:0045730]; superoxide metabolic process [GO:0006801]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	chemotaxis [GO:0006935]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; viral RNA genome replication [GO:0039694]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; immune response [GO:0006955]; oxidation-reduction process [GO:0055114]; phagocytosis [GO:0006909]; respiratory burst [GO:0045730]; superoxide metabolic process [GO:0006801]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; membrane [GO:0016020]; NADPH oxidase complex [GO:0043020]; phagolysosome [GO:0032010]	1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol phosphate kinase activity [GO:0016307]	phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol binding [GO:0035091]; protein dimerization activity [GO:0046983]; superoxide-generating NADPH oxidase activator activity [GO:0016176]
d2wwfa1_d4as7a___1		Metazoa	Apicomplexa	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	cytosol [GO:0005829]; kinesin complex [GO:0005871]; membrane [GO:0016020]; microtubule [GO:0005874]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; ATP binding [GO:0005524]; ATP-dependent microtubule motor activity, plus-end-directed [GO:0008574]; ATPase activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; protein kinase binding [GO:0019901]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; regulation of mitotic centrosome separation [GO:0046602]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; spindle organization [GO:0007051]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; regulation of mitotic centrosome separation [GO:0046602]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; spindle organization [GO:0007051]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytosol [GO:0005829]; kinesin complex [GO:0005871]; membrane [GO:0016020]; microtubule [GO:0005874]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; ATP-dependent microtubule motor activity, plus-end-directed [GO:0008574]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; protein kinase binding [GO:0019901]
d2wwga__d4uj5b___1		Metazoa	Apicomplexa	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; identical protein binding [GO:0042802]; Rab guanyl-nucleotide exchange factor activity [GO:0017112]; ciliary basal body-plasma membrane docking [GO:0097711]; cilium assembly [GO:0060271]; Golgi to plasma membrane transport [GO:0006893]; protein localization to organelle [GO:0033365]; protein targeting to membrane [GO:0006612]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	ciliary basal body-plasma membrane docking [GO:0097711]; cilium assembly [GO:0060271]; Golgi to plasma membrane transport [GO:0006893]; protein localization to organelle [GO:0033365]; protein targeting to membrane [GO:0006612]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; nucleus [GO:0005634]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	identical protein binding [GO:0042802]; Rab guanyl-nucleotide exchange factor activity [GO:0017112]
d2wwhc__d1xxhd2__1			Apicomplexa	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA-dependent DNA replication [GO:0006261]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	DNA-dependent DNA replication [GO:0006261]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	DNA polymerase III complex [GO:0009360]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d2wwia__d3gj3a___1		Metazoa	Apicomplexa	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2wwjb__d3v17a___1	Metazoa		Chordata	Proteobacteria	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]		histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]
d2wwza__d2fnjb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	elongin complex [GO:0070449]; VCB complex [GO:0030891]; protein-containing complex binding [GO:0044877]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	elongin complex [GO:0070449]; VCB complex [GO:0030891]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	protein-containing complex binding [GO:0044877]
d2wwza__d2lxaa1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]; cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]
d2wxua2_d3o8yb1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nuclear envelope [GO:0005635]; nuclear envelope lumen [GO:0005641]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]; arachidonate 5-lipoxygenase activity [GO:0004051]; iron ion binding [GO:0005506]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-18-mediated signaling pathway [GO:0035655]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]	hemolysis in other organism [GO:0044179]	cytokine-mediated signaling pathway [GO:0019221]; interleukin-18-mediated signaling pathway [GO:0035655]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nuclear envelope [GO:0005635]; nuclear envelope lumen [GO:0005641]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]	hydrolase activity [GO:0016787]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	arachidonate 5-lipoxygenase activity [GO:0004051]; iron ion binding [GO:0005506]
d2wxvd2_d2wevb1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2wyka1_d5on0b___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	outer membrane-bounded periplasmic space [GO:0030288]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]
d2wyka1_d5ubhb___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	histidine biosynthetic process [GO:0000105]	outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d2wypa1_d3tyhe___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]		metal ion binding [GO:0046872]
d2wyuc__d1ntoc2__1			Deinococcus-Thermus	Crenarchaeota	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]	fatty acid biosynthetic process [GO:0006633]				enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]
d2wyva__d4l76b1__1			Deinococcus-Thermus	Euryarchaeota	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	fatty acid biosynthetic process [GO:0006633]	potassium ion transport [GO:0006813]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2wywc__d3ikvb2__1			Deinococcus-Thermus	Deinococcus-Thermus	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]	fatty acid biosynthetic process [GO:0006633]	negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]		cytoplasm [GO:0005737]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]	coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2wywd__d3hdhc2__1		Metazoa	Deinococcus-Thermus	Chordata	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; positive regulation of cold-induced thermogenesis [GO:0120162]	fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation [GO:0006635]; positive regulation of cold-induced thermogenesis [GO:0120162]		mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d2wz6f__d2jlpa___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; heparin binding [GO:0008201]; superoxide dismutase activity [GO:0004784]; cellular response to oxidative stress [GO:0034599]; removal of superoxide radicals [GO:0019430]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cellular response to oxidative stress [GO:0034599]; removal of superoxide radicals [GO:0019430]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; heparin binding [GO:0008201]; superoxide dismutase activity [GO:0004784]
d2wz9a__d3a2vh___1	Metazoa		Chordata	Crenarchaeota	cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; [2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	[2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]	cell [GO:0005623]; cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2wzla__d1vyia___1			Negarnaviricota	Negarnaviricota	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; virion [GO:0019012]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral transcription [GO:0019083]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; virion [GO:0019012]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral entry into host cell [GO:0046718]; viral transcription [GO:0019083]	suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral transcription [GO:0019083]	microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral entry into host cell [GO:0046718]; viral transcription [GO:0019083]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; virion [GO:0019012]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; virion [GO:0019012]	RNA-directed 5'-3' RNA polymerase activity [GO:0003968]	RNA-directed 5'-3' RNA polymerase activity [GO:0003968]
d2wzpe1_d1mrfl2__1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		virus tail, baseplate [GO:0098025]			
d2wzpf1_d1yylq1__1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d2wzr3__d1pov3___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2wzr3__d4y5zr___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d2wzya1_d2xz6f___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2wzyc1_d3u8lb___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2wzyc1_d4bfqe___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2wzye1_d2xnvh___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2wzyf1_d3wtje1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2wzyh1_d1uv6b___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2wzyj1_d3sq9e___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d2x00a1_d3t4mc1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2x00a1_d4zrue___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2x00d__d2ymej___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2x00d__d4zjti1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2x05a1_d1jyvb3__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2x05a3_d1dhka2__1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d2x05a3_d2g3ia___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	endo-1,4-beta-xylanase activity [GO:0031176]
d2x05a4_d3dyma2__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2x05a5_d1f4ac1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2x05a5_d3t0ad4__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2x05b2_d3dyoa4__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2x05b3_d2vmfa5__1			Actinobacteria	Bacteroidetes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-mannosidase activity [GO:0004567]
d2x05b4_d3iapc4__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2x07a__d1ddxa1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d2x08a__d3wnua1__1	Fungi		Ascomycota	Cyanobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2x09a2_d3t2qb4__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2x09a4_d3k4da2__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	extracellular region [GO:0005576]	cytosol [GO:0005829]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d2x09a5_d3t0aa4__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2x09b1_d2y6ha1__1			Actinobacteria	Bacteroidetes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2x09b3_d1x39a1__1		Viridiplantae	Actinobacteria	Streptophyta	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2x09b3_d3vd9c3__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2x09b4_d2vzob5__1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2x09b5_d1f4hb2__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2x09b5_d4jkla2__1			Actinobacteria	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2x0aa__d233la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2x0ia2_d4ajld2__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2x0na2_d2b4tq2__1				Apicomplexa	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glycosome [GO:0020015]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2x0nr2_d1ebfb2__1		Fungi		Ascomycota	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; homoserine dehydrogenase activity [GO:0004412]; NADP binding [GO:0050661]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	glycosome [GO:0020015]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	homoserine dehydrogenase activity [GO:0004412]; NADP binding [GO:0050661]
d2x0ra2_d1sevb2__1		Viridiplantae	Euryarchaeota	Streptophyta	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	glyoxysome [GO:0009514]	L-malate dehydrogenase activity [GO:0030060]	L-malate dehydrogenase activity [GO:0030060]
d2x0yb2_d2vt0a2__1		Metazoa	Firmicutes	Chordata	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d2x173__d5l8bg___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]
d2x174__d3ak8d___1			Euryarchaeota		cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]	
d2x176__d2iy4u___1			Euryarchaeota	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2x178__d5d8ok___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2x17g__d1t0rb___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]		ferric iron binding [GO:0008199]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d2x17h__d3np2x___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2x17j__d2v15f___1			Euryarchaeota	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d2x17l__d1mfrs___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2x17n__d2htnf___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2x17n__d3oj5i___1			Euryarchaeota	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]
d2x17o__d1xvcb___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2x17o__d3a9qb___1		Viridiplantae	Euryarchaeota	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2x17q__d2iy4d___1			Euryarchaeota	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2x17r__d3ka4a___1		Metazoa	Euryarchaeota	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2x17z__d1oqba___1		Viridiplantae	Euryarchaeota	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]	chloroplast [GO:0009507]	ferric iron binding [GO:0008199]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d2x18c__d2yvca2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]; ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; intracellular signal transduction [GO:0035556]; mitochondrial genome maintenance [GO:0000002]; negative regulation of cellular senescence [GO:2000773]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	intracellular signal transduction [GO:0035556]; mitochondrial genome maintenance [GO:0000002]; negative regulation of cellular senescence [GO:2000773]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d2x18f__d2zpya2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]; ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; intracellular signal transduction [GO:0035556]; mitochondrial genome maintenance [GO:0000002]; negative regulation of cellular senescence [GO:2000773]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	intracellular signal transduction [GO:0035556]; mitochondrial genome maintenance [GO:0000002]; negative regulation of cellular senescence [GO:2000773]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d2x19a__d5cj2h___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nucleus organization [GO:0006997]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein import into nucleus [GO:0006606]; regulation of chromatin silencing at telomere [GO:0031938]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nucleus organization [GO:0006997]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein import into nucleus [GO:0006606]; regulation of chromatin silencing at telomere [GO:0031938]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2x1aa__d4iufa___1	Fungi	Metazoa	Ascomycota	Chordata	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; mRNA binding [GO:0003729]; mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	cytoplasmic stress granule [GO:0010494]; interchromatin granule [GO:0035061]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; DNA-binding transcription factor activity [GO:0003700]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; mRNA 3'-UTR binding [GO:0003730]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA processing [GO:0006397]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; nuclear inner membrane organization [GO:0071765]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein import into nucleus [GO:0042307]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of protein stability [GO:0031647]; response to endoplasmic reticulum stress [GO:0034976]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]; transcription by RNA polymerase II [GO:0006366]	mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA processing [GO:0006397]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; nuclear inner membrane organization [GO:0071765]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein import into nucleus [GO:0042307]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of protein stability [GO:0031647]; response to endoplasmic reticulum stress [GO:0034976]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]; transcription by RNA polymerase II [GO:0006366]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]	cytoplasmic stress granule [GO:0010494]; interchromatin granule [GO:0035061]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	mRNA binding [GO:0003729]	DNA-binding transcription factor activity [GO:0003700]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; mRNA 3'-UTR binding [GO:0003730]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]
d2x1aa__d5tbxa___1	Fungi	Metazoa	Ascomycota	Chordata	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; mRNA binding [GO:0003729]; mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; translation repressor activity [GO:0030371]; mRNA stabilization [GO:0048255]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of translation [GO:0045727]; response to cold [GO:0009409]; response to UV [GO:0009411]; stress granule assembly [GO:0034063]	mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; response to DNA damage checkpoint signaling [GO:0072423]	mRNA stabilization [GO:0048255]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of translation [GO:0045727]; response to cold [GO:0009409]; response to UV [GO:0009411]; stress granule assembly [GO:0034063]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	mRNA binding [GO:0003729]	mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; translation repressor activity [GO:0030371]
d2x1la1_d3hzrb___1			Actinobacteria		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	methionyl-tRNA aminoacylation [GO:0006431]	tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d2x1la1_d3kt8d___1		Fungi	Actinobacteria	Ascomycota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	methionyl-tRNA aminoacylation [GO:0006431]	tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d2x1lb1_d1p7pa1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d2x1ma2_d4eg1a2__1			Actinobacteria		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]	ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]
d2x1ob1_d2g75a1__1												
d2x1ub__d4bi7a___1					cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytoplasm [GO:0005737]	triose-phosphate isomerase activity [GO:0004807]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]
d2x23b__d1pwxc___1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	
d2x23e__d1f14b2__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d2x23g__d1hwzb1__1			Actinobacteria		cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	
d2x2ba__d2l0qa1__1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]	lipid A biosynthetic process [GO:0009245]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]	acyl carrier activity [GO:0000036]
d2x2wb__d3zzfb___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; cellular response to DNA damage stimulus [GO:0006974]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]; cellular response to DNA damage stimulus [GO:0006974]	arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]	acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]
d2x2ya1_d3muy23__1			Actinobacteria	Proteobacteria	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2x2yb1_d1lwja2__1			Actinobacteria	Thermotogae	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]; oligosaccharide catabolic process [GO:0009313]	cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	oligosaccharide catabolic process [GO:0009313]		cytoplasm [GO:0005737]	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]	4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]
d2x3eb1_d1hzpa1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d2x3ya1_d3hjbb1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	cytosol [GO:0005829]; glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]	glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d2x3yb__d1kojb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]
d2x3yf__d1g98b___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]
d2x41a1_d1uksb4__1			Thermotogae	Firmicutes	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2x41a3_d3ac0d4__1		Fungi	Thermotogae	Ascomycota	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d2x44d__d3cxhv___1	Metazoa	Fungi	Chordata	Ascomycota	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]		
d2x4nb1_d4rdqn1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]; chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2x4ob1_d5gzod2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2x4pb1_d3hmxl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]; cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d2x4pe1_d5wccl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2x4ub1_d3o4le2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2x5dd__d4y0hc___1		Metazoa	Proteobacteria	Chordata	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	biosynthetic process [GO:0009058]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]		4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]
d2x5ia__d1piv3___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2x5ic__d1c8nc___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d2x64b2_d5ecnf2__1		Viridiplantae	Proteobacteria	Streptophyta	transferase activity [GO:0016740]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]		glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]		apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	transferase activity [GO:0016740]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2x64c2_d5f06b2__1		Viridiplantae	Proteobacteria	Streptophyta	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]		glutathione metabolic process [GO:0006749]		cytoplasm [GO:0005737]	transferase activity [GO:0016740]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d2x64d1_d1f6mg___1			Proteobacteria	Proteobacteria	transferase activity [GO:0016740]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	transferase activity [GO:0016740]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d2x64d1_d4nhzh1__1			Proteobacteria	Proteobacteria	transferase activity [GO:0016740]	transferase activity [GO:0016740]					transferase activity [GO:0016740]	transferase activity [GO:0016740]
d2x64e1_d2lsta1__1			Proteobacteria	Deinococcus-Thermus	transferase activity [GO:0016740]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]	transferase activity [GO:0016740]	
d2x64f1_d1uulf___1			Proteobacteria		transferase activity [GO:0016740]						transferase activity [GO:0016740]	
d2x6gh__d2q8tc___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium-dependent protein kinase C activity [GO:0004698]; CCR chemokine receptor binding [GO:0048020]; CCR1 chemokine receptor binding [GO:0031726]; CCR5 chemokine receptor binding [GO:0031730]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; phospholipase activator activity [GO:0016004]; protein kinase activity [GO:0004672]; astrocyte cell migration [GO:0043615]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell activation [GO:0001775]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; eosinophil degranulation [GO:0043308]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; granulocyte chemotaxis [GO:0071621]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of bone mineralization [GO:0030502]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast differentiation [GO:0045671]; neutrophil chemotaxis [GO:0030593]; osteoblast differentiation [GO:0001649]; positive regulation of calcium ion import [GO:0090280]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; protein kinase B signaling [GO:0043491]; regulation of behavior [GO:0050795]; regulation of cell shape [GO:0008360]; regulation of sensory perception of pain [GO:0051930]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to cholesterol [GO:0070723]; response to toxic substance [GO:0009636]; signaling [GO:0023052]; T cell chemotaxis [GO:0010818]	cell [GO:0005623]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	astrocyte cell migration [GO:0043615]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell activation [GO:0001775]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; eosinophil degranulation [GO:0043308]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; granulocyte chemotaxis [GO:0071621]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of bone mineralization [GO:0030502]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast differentiation [GO:0045671]; neutrophil chemotaxis [GO:0030593]; osteoblast differentiation [GO:0001649]; positive regulation of calcium ion import [GO:0090280]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; protein kinase B signaling [GO:0043491]; regulation of behavior [GO:0050795]; regulation of cell shape [GO:0008360]; regulation of sensory perception of pain [GO:0051930]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to cholesterol [GO:0070723]; response to toxic substance [GO:0009636]; signaling [GO:0023052]; T cell chemotaxis [GO:0010818]	cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell [GO:0005623]; extracellular space [GO:0005615]	calcium-dependent protein kinase C activity [GO:0004698]; CCR1 chemokine receptor binding [GO:0031726]; CCR5 chemokine receptor binding [GO:0031730]; CCR chemokine receptor binding [GO:0048020]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; phospholipase activator activity [GO:0016004]; protein kinase activity [GO:0004672]	CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]
d2x6ma__d2rfxb___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; axon [GO:0030424]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; inclusion body [GO:0016234]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; ribosome [GO:0005840]; rough endoplasmic reticulum [GO:0005791]; supramolecular fiber [GO:0099512]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; actin binding [GO:0003779]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cuprous ion binding [GO:1903136]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; dynein complex binding [GO:0070840]; ferrous iron binding [GO:0008198]; histone binding [GO:0042393]; Hsp70 protein binding [GO:0030544]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; oxidoreductase activity [GO:0016491]; phospholipase binding [GO:0043274]; phospholipid binding [GO:0005543]; phosphoprotein binding [GO:0051219]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; SNARE binding [GO:0000149]; tau protein binding [GO:0048156]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; adult locomotory behavior [GO:0008344]; aging [GO:0007568]; behavioral response to cocaine [GO:0048148]; cellular protein metabolic process [GO:0044267]; cellular response to copper ion [GO:0071280]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to oxidative stress [GO:0034599]; dopamine biosynthetic process [GO:0042416]; dopamine uptake involved in synaptic transmission [GO:0051583]; excitatory postsynaptic potential [GO:0060079]; fatty acid metabolic process [GO:0006631]; long-term synaptic potentiation [GO:0060291]; microglial cell activation [GO:0001774]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrial membrane organization [GO:0007006]; negative regulation of apoptotic process [GO:0043066]; negative regulation of chaperone-mediated autophagy [GO:1904715]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of dopamine uptake involved in synaptic transmission [GO:0051585]; negative regulation of exocytosis [GO:0045920]; negative regulation of histone acetylation [GO:0035067]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902957]; negative regulation of monooxygenase activity [GO:0032769]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of norepinephrine uptake [GO:0051622]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of serotonin uptake [GO:0051612]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transporter activity [GO:0032410]; neutral lipid metabolic process [GO:0006638]; oxidation-reduction process [GO:0055114]; phospholipid metabolic process [GO:0006644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endocytosis [GO:0045807]; positive regulation of exocytosis [GO:0045921]; positive regulation of glutathione peroxidase activity [GO:1903284]; positive regulation of hydrogen peroxide catabolic process [GO:1903285]; positive regulation of inflammatory response [GO:0050729]; positive regulation of inositol phosphate biosynthetic process [GO:0060732]; positive regulation of neuron death [GO:1901216]; positive regulation of neurotransmitter secretion [GO:0001956]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of receptor recycling [GO:0001921]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; protein destabilization [GO:0031648]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of acyl-CoA biosynthetic process [GO:0050812]; regulation of dopamine secretion [GO:0014059]; regulation of glutamate secretion [GO:0014048]; regulation of locomotion [GO:0040012]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of macrophage activation [GO:0043030]; regulation of norepinephrine uptake [GO:0051621]; regulation of phospholipase activity [GO:0010517]; regulation of presynapse assembly [GO:1905606]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; regulation of synaptic vesicle recycling [GO:1903421]; regulation of transmembrane transporter activity [GO:0022898]; response to desipramine [GO:1904307]; response to interferon-gamma [GO:0034341]; response to interleukin-1 [GO:0070555]; response to iron(II) ion [GO:0010040]; response to lipopolysaccharide [GO:0032496]; response to magnesium ion [GO:0032026]; SNARE complex assembly [GO:0035493]; supramolecular fiber organization [GO:0097435]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; adult locomotory behavior [GO:0008344]; aging [GO:0007568]; behavioral response to cocaine [GO:0048148]; cellular protein metabolic process [GO:0044267]; cellular response to copper ion [GO:0071280]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to oxidative stress [GO:0034599]; dopamine biosynthetic process [GO:0042416]; dopamine uptake involved in synaptic transmission [GO:0051583]; excitatory postsynaptic potential [GO:0060079]; fatty acid metabolic process [GO:0006631]; long-term synaptic potentiation [GO:0060291]; microglial cell activation [GO:0001774]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrial membrane organization [GO:0007006]; negative regulation of apoptotic process [GO:0043066]; negative regulation of chaperone-mediated autophagy [GO:1904715]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of dopamine uptake involved in synaptic transmission [GO:0051585]; negative regulation of exocytosis [GO:0045920]; negative regulation of histone acetylation [GO:0035067]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902957]; negative regulation of monooxygenase activity [GO:0032769]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of norepinephrine uptake [GO:0051622]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of serotonin uptake [GO:0051612]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transporter activity [GO:0032410]; neutral lipid metabolic process [GO:0006638]; oxidation-reduction process [GO:0055114]; phospholipid metabolic process [GO:0006644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endocytosis [GO:0045807]; positive regulation of exocytosis [GO:0045921]; positive regulation of glutathione peroxidase activity [GO:1903284]; positive regulation of hydrogen peroxide catabolic process [GO:1903285]; positive regulation of inflammatory response [GO:0050729]; positive regulation of inositol phosphate biosynthetic process [GO:0060732]; positive regulation of neuron death [GO:1901216]; positive regulation of neurotransmitter secretion [GO:0001956]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of receptor recycling [GO:0001921]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; protein destabilization [GO:0031648]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of acyl-CoA biosynthetic process [GO:0050812]; regulation of dopamine secretion [GO:0014059]; regulation of glutamate secretion [GO:0014048]; regulation of locomotion [GO:0040012]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of macrophage activation [GO:0043030]; regulation of norepinephrine uptake [GO:0051621]; regulation of phospholipase activity [GO:0010517]; regulation of presynapse assembly [GO:1905606]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; regulation of synaptic vesicle recycling [GO:1903421]; regulation of transmembrane transporter activity [GO:0022898]; response to desipramine [GO:1904307]; response to interferon-gamma [GO:0034341]; response to interleukin-1 [GO:0070555]; response to iron(II) ion [GO:0010040]; response to lipopolysaccharide [GO:0032496]; response to magnesium ion [GO:0032026]; SNARE complex assembly [GO:0035493]; supramolecular fiber organization [GO:0097435]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin cytoskeleton [GO:0015629]; axon [GO:0030424]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; inclusion body [GO:0016234]; lysosome [GO:0005764]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; ribosome [GO:0005840]; rough endoplasmic reticulum [GO:0005791]; supramolecular fiber [GO:0099512]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	actin binding [GO:0003779]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cuprous ion binding [GO:1903136]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; dynein complex binding [GO:0070840]; ferrous iron binding [GO:0008198]; histone binding [GO:0042393]; Hsp70 protein binding [GO:0030544]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; oxidoreductase activity [GO:0016491]; phospholipase binding [GO:0043274]; phospholipid binding [GO:0005543]; phosphoprotein binding [GO:0051219]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; SNARE binding [GO:0000149]; tau protein binding [GO:0048156]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2x6td__d1dfhb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; membrane [GO:0016020]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]
d2x6te__d3gy0a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]		cytosol [GO:0005829]; membrane [GO:0016020]		ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2x6tf__d2i9pa1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	mitochondrial matrix [GO:0005759]; 3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574]	cytosol [GO:0005829]; membrane [GO:0016020]	mitochondrial matrix [GO:0005759]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d2x6tg__d1zk3b___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]		cytosol [GO:0005829]; membrane [GO:0016020]		ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2x6th__d5cp8a___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; membrane [GO:0016020]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d2x6tj__d5i7vc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; membrane [GO:0016020]		ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP+ binding [GO:0070401]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d2x70e1_d1h0da2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]
d2x70e1_d4fg6f1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of plasma membrane [GO:0005887]; antiporter activity [GO:0015297]; voltage-gated chloride channel activity [GO:0005247]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of plasma membrane [GO:0005887]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antiporter activity [GO:0015297]; voltage-gated chloride channel activity [GO:0005247]
d2x7ka__d2mzua___1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 2 spliceosome [GO:0071007]; cyclosporin A binding [GO:0016018]; disordered domain specific binding [GO:0097718]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 2 spliceosome [GO:0071007]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cyclosporin A binding [GO:0016018]; disordered domain specific binding [GO:0097718]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d2x7wa__d1bxbb___1			Thermotogae	Deinococcus-Thermus	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	base-excision repair [GO:0006284]	D-xylose metabolic process [GO:0042732]		cytoplasm [GO:0005737]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d2x7wa__d5nh6b___1		Fungi	Thermotogae	Chytridiomycota	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	base-excision repair [GO:0006284]	xylose catabolic process to ethanol [GO:0044577]			deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d2x80b__d2q6ne1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	endoplasmic reticulum membrane [GO:0005789]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			cytoplasm [GO:0005737]	endoplasmic reticulum membrane [GO:0005789]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2x82d__d3h4eh1__1						host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2x86a__d1o89a2__1			Proteobacteria	Proteobacteria	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytoplasm [GO:0005737]; acryloyl-CoA reductase (NADP+) activity [GO:0043957]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]			cytoplasm [GO:0005737]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]	acryloyl-CoA reductase (NADP+) activity [GO:0043957]
d2x86c__d2cdhl1__1			Proteobacteria	Proteobacteria	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d2x86c__d3aoeb2__1			Proteobacteria	Deinococcus-Thermus	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cellular amino acid metabolic process [GO:0006520]			ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d2x86f__d5t2uc1__1			Proteobacteria	Actinobacteria	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	nucleotide binding [GO:0000166]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]				ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]	nucleotide binding [GO:0000166]
d2x86k__d1gega___1			Proteobacteria	Proteobacteria	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; acetoin catabolic process [GO:0045150]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	acetoin catabolic process [GO:0045150]			ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]	diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]
d2x86r__d3wswa1__1			Proteobacteria	Firmicutes	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; glycolytic process [GO:0006096]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d2x86s__d1wzib1__1			Proteobacteria	Deinococcus-Thermus	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]			ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]	L-malate dehydrogenase activity [GO:0030060]
d2x86t__d1mp0b2__1		Metazoa	Proteobacteria	Chordata	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]
d2x87a2_d1tsaa___1			Firmicutes		outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	
d2x87a3_d4akoa2__1			Firmicutes	Firmicutes	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]	outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2x88a2_d2tsab___1			Firmicutes	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	sporulation resulting in formation of a cellular spore [GO:0030435]	oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2x89a1_d3cd4a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d2x89b1_d2icwd1__1	Metazoa		Chordata	Tenericutes	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2x89c1_d12e8m1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2x89d1_d3c6le1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2x89d1_d3cfkp2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2x89f1_d1jnhc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	plasma membrane [GO:0005886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2x8rb__d1px8b2__1	Fungi		Ascomycota	Firmicutes	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	xylan catabolic process [GO:0045493]			lysozyme activity [GO:0003796]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d2x8rc__d1f49b5__1	Fungi		Ascomycota		lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]		cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]				lysozyme activity [GO:0003796]	
d2x8rc__d3scta___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	lysozyme activity [GO:0003796]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d2x8rd__d1w2pa___1	Fungi		Ascomycota	Proteobacteria	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	xylan catabolic process [GO:0045493]			lysozyme activity [GO:0003796]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]
d2x8re__d2cyga1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; carbohydrate metabolic process [GO:0005975]	cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	carbohydrate metabolic process [GO:0005975]			lysozyme activity [GO:0003796]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]
d2x8wa__d1wo8d___1			Deinococcus-Thermus	Deinococcus-Thermus	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]	methylglyoxal biosynthetic process [GO:0019242]			methylglyoxal synthase activity [GO:0008929]	methylglyoxal synthase activity [GO:0008929]
d2x90a__d3elmb___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; sperm individualization [GO:0007291]; spermatid nucleus differentiation [GO:0007289]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; spermatid nucleus differentiation [GO:0007289]; sperm individualization [GO:0007291]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d2x92a__d3scja___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; sperm individualization [GO:0007291]; spermatid nucleus differentiation [GO:0007289]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; spermatid nucleus differentiation [GO:0007289]; sperm individualization [GO:0007291]	angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d2x94a__d2o3ea___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; sperm individualization [GO:0007291]; spermatid nucleus differentiation [GO:0007289]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; oligopeptidase activity [GO:0070012]; peptide metabolic process [GO:0006518]; proteolysis [GO:0006508]	metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; spermatid nucleus differentiation [GO:0007289]; sperm individualization [GO:0007291]	peptide metabolic process [GO:0006518]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; oligopeptidase activity [GO:0070012]
d2x94a__d5un3a___1	Metazoa		Arthropoda	Firmicutes	extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; sperm individualization [GO:0007291]; spermatid nucleus differentiation [GO:0007289]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; spermatid nucleus differentiation [GO:0007289]; sperm individualization [GO:0007291]		extracellular space [GO:0005615]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d2x9aa__d1tola1__1			Proteobacteria		integral component of membrane [GO:0016021]; toxin transmembrane transporter activity [GO:0019534]; bacteriocin transport [GO:0043213]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; pathogenesis [GO:0009405]; viral entry into host cell via pilus retraction [GO:0039667]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	bacteriocin transport [GO:0043213]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; pathogenesis [GO:0009405]; viral entry into host cell via pilus retraction [GO:0039667]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	integral component of membrane [GO:0016021]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]	toxin transmembrane transporter activity [GO:0019534]	
d2x9da1_d3fk7a1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d2xa3a__d1jtpa___1		Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; extracellular space [GO:0005615]		glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2xa8l1_d43cad___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2xafa3_d1bf3a2__1	Metazoa		Chordata	Proteobacteria	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	benzoate catabolic process via hydroxylation [GO:0043640]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]		DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d2xaha3_d1daoc2__1	Metazoa	Metazoa	Chordata	Chordata	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d2xaja3_d1n4wa2__1	Metazoa		Chordata	Actinobacteria	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cholesterol metabolic process [GO:0008203]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	extracellular region [GO:0005576]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]
d2xaqa3_d3cphg3__1	Metazoa	Fungi	Chordata	Ascomycota	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cytoplasm [GO:0005737]; GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]
d2xb5a1_d3br3a1__1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2xb6d__d1lod.3__1	Metazoa	Viridiplantae	Chordata	Streptophyta	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	mannose binding [GO:0005537]	angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]		axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]	mannose binding [GO:0005537]
d2xb6d__d5ik5a2__1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]	signaling receptor binding [GO:0005102]
d2xb8a__d5yl5g___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d2xbla__d1jiqa___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d2xblb__d1vivb1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	carbohydrate derivative binding [GO:0097367]; hexulose-6-phosphate isomerase activity [GO:0043800]; carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]; formaldehyde assimilation via ribulose monophosphate cycle [GO:0019647]; response to toxic substance [GO:0009636]	capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]; formaldehyde assimilation via ribulose monophosphate cycle [GO:0019647]; response to toxic substance [GO:0009636]	cytoplasm [GO:0005737]		carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]	carbohydrate derivative binding [GO:0097367]; hexulose-6-phosphate isomerase activity [GO:0043800]
d2xbmc__d1r6aa___1					host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2xbqb__d2vcwb2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cell [GO:0005623]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d2xbsa__d1l53a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2xbta__d1c7sa2__1			Firmicutes	Proteobacteria	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		periplasmic space [GO:0042597]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]
d2xbva__d1lvoe___1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2xc5a__d3zzda___1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2xcdc__d3gf0a___1			Firmicutes	Euryarchaeota	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d2xcdd__d1xs6a___1			Firmicutes	Proteobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]		cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d2xcde__d1duda1__1			Firmicutes	Proteobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2xcea__d2v9xf___1			Firmicutes	Proteobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]		cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d2xceb__d3c3ib___1			Firmicutes		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2xcec__d2we1a1__1			Firmicutes		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP metabolic process [GO:0046080]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]
d2xcec__d3tpna___1			Firmicutes		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]		viral nucleocapsid [GO:0019013]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d2xcga2_d1n4ua2__1	Metazoa		Chordata	Actinobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cholesterol metabolic process [GO:0008203]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]
d2xcgb2_d1kife2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d2xcma1_d3ow6a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; cellular response to auxin stimulus [GO:0071365]; defense response [GO:0006952]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; protein stabilization [GO:0050821]; regulation of defense response to fungus, incompatible interaction [GO:2000072]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cellular response to auxin stimulus [GO:0071365]; defense response [GO:0006952]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; protein stabilization [GO:0050821]; regulation of defense response to fungus, incompatible interaction [GO:2000072]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d2xcmb1_d1i59b___1	Viridiplantae		Streptophyta	Thermotogae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; cellular response to auxin stimulus [GO:0071365]; defense response [GO:0006952]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; protein stabilization [GO:0050821]; regulation of defense response to fungus, incompatible interaction [GO:2000072]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]; chemotaxis [GO:0006935]	cellular response to auxin stimulus [GO:0071365]; defense response [GO:0006952]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; protein stabilization [GO:0050821]; regulation of defense response to fungus, incompatible interaction [GO:2000072]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]	chemotaxis [GO:0006935]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; protein domain specific binding [GO:0019904]
d2xd2a__d5mm3a___1			Firmicutes	Proteobacteria	plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	plasma membrane [GO:0005886]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	carbohydrate transmembrane transporter activity [GO:0015144]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d2xd9a__d4rc9e___1			Proteobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d2xdka__d5d7da___1	Metazoa		Chordata	Firmicutes	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d2xdra__d2qe0a___1			Proteobacteria	Firmicutes	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	glycine betaine biosynthetic process from choline [GO:0019285]				aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]
d2xdrb__d1bpwa___1		Metazoa	Proteobacteria	Chordata	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	cytosol [GO:0005829]; 4-trimethylammoniobutyraldehyde dehydrogenase activity [GO:0047105]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; carnitine biosynthetic process [GO:0045329]	glycine betaine biosynthetic process from choline [GO:0019285]	carnitine biosynthetic process [GO:0045329]		cytosol [GO:0005829]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	4-trimethylammoniobutyraldehyde dehydrogenase activity [GO:0047105]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]
d2xe0a__d1g9za___1		Viridiplantae		Chlorophyta		chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]		intron homing [GO:0006314]		chloroplast [GO:0009507]		endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2xewh__d2dzia1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	BAT3 complex [GO:0071818]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chaperone binding [GO:0051087]; ubiquitin-like protein transferase activity [GO:0019787]; cellular protein modification process [GO:0006464]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein modification process [GO:0006464]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	BAT3 complex [GO:0071818]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	chaperone binding [GO:0051087]; ubiquitin-like protein transferase activity [GO:0019787]
d2xewk__d2al6b3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]; actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]
d2xffa__d2g4fb___1	Viridiplantae		Streptophyta	Actinobacteria	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; identical protein binding [GO:0042802]; polysaccharide catabolic process [GO:0000272]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; identical protein binding [GO:0042802]	endo-1,4-beta-xylanase activity [GO:0031176]
d2xflb__d4b0cb___1			Actinobacteria	Proteobacteria		cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]		unsaturated fatty acid biosynthetic process [GO:0006636]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]
d2xflc__d3azag___1			Actinobacteria	Apicomplexa		hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]
d2xfld__d4gwhg3__1			Actinobacteria									
d2xfle__d2ownb2__1			Actinobacteria	Firmicutes		myristoyl-[acyl-carrier-protein] hydrolase activity [GO:0016295]; oleoyl-[acyl-carrier-protein] hydrolase activity [GO:0004320]; palmitoyl-[acyl-carrier-protein] hydrolase activity [GO:0016296]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]				myristoyl-[acyl-carrier-protein] hydrolase activity [GO:0016295]; oleoyl-[acyl-carrier-protein] hydrolase activity [GO:0004320]; palmitoyl-[acyl-carrier-protein] hydrolase activity [GO:0016296]
d2xflf__d3f5oc___1		Metazoa	Actinobacteria	Chordata		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]; acyl-CoA hydrolase activity [GO:0047617]; acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]		acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]		acyl-CoA hydrolase activity [GO:0047617]
d2xfpa2_d1daof2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d2xfpb2_d4uvaa3__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d2xfqa2_d1cj2a2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d2xfub2_d1ykja2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	benzoate catabolic process via hydroxylation [GO:0043640]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d2xg4a1_d1grwc___1		Metazoa	Proteobacteria	Nematoda (roundworms)	outer membrane-bounded periplasmic space [GO:0030288]; cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]	cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]		outer membrane-bounded periplasmic space [GO:0030288]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; pseudopodium [GO:0031143]		
d2xg4b__d2m5ga___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	pilus [GO:0009289]; identical protein binding [GO:0042802]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	outer membrane-bounded periplasmic space [GO:0030288]	pilus [GO:0009289]		identical protein binding [GO:0042802]
d2xg4b__d4xoda1__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	outer membrane-bounded periplasmic space [GO:0030288]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d2xgba__d3t2qb3__1	Viridiplantae		Streptophyta	Proteobacteria	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; identical protein binding [GO:0042802]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; identical protein binding [GO:0042802]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2xgpb2_d2va2a1__1	Fungi		Ascomycota	Crenarchaeota	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d2xgqb2_d1s0oa1__1	Fungi		Ascomycota	Crenarchaeota	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d2xgzb2_d4m6ua2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d2xh0b2_d1sjca1__1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	menaquinone biosynthetic process [GO:0009234]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d2xh0c2_d5fjtc2__1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	menaquinone biosynthetic process [GO:0009234]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d2xh2c2_d1r0md1__1	Fungi		Ascomycota	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	menaquinone biosynthetic process [GO:0009234]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d2xh4a1_d3dfha1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cellular amino acid catabolic process [GO:0009063]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]
d2xh4a1_d3ujfa1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2xh4c1_d3ujsb1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d2xh4c2_d3vcna2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d2xh6a2_d2y64a1__1			Firmicutes	Bacteroidetes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		toxin activity [GO:0090729]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2xh7b1_d3uxlb1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d2xhfb__d3f6da1__1	Metazoa	Metazoa	Annelida	Arthropoda	peroxiredoxin activity [GO:0051920]	transferase activity [GO:0016740]					peroxiredoxin activity [GO:0051920]	transferase activity [GO:0016740]
d2xhfb__d4kb3j___1	Metazoa		Annelida		peroxiredoxin activity [GO:0051920]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]	peroxiredoxin activity [GO:0051920]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d2xhia1_d1qnbb1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d2xhia1_d1vtob2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d2xhia2_d3cvtc1__1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d2xhnb1_d3l4ua1__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]
d2xhnb3_d3t2qa1__1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2xi6a__d4c50a1__1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]
d2xifa__d5l05a2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]		heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2xigc__d1u2wc___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]; negative regulation of siderophore biosynthetic process [GO:1900705]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of secondary metabolite biosynthetic process [GO:1900376]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; response to cadmium ion [GO:0046686]	negative regulation of siderophore biosynthetic process [GO:1900705]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of secondary metabolite biosynthetic process [GO:1900376]	response to cadmium ion [GO:0046686]	cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]
d2ximb__d5nh9b___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d2ximc__d1a0dc___1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d2ximd__d4xkme___1			Actinobacteria	Bacteroidetes	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d2xina__d2nqha___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	D-xylose metabolic process [GO:0042732]	base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]
d2xiub__d1zz8a1__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]			DNA binding [GO:0003677]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d2xj0a__d2whbc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; manganese ion binding [GO:0030145]; protein serine/threonine kinase activity [GO:0004674]; ribosomal small subunit binding [GO:0043024]; transcription factor binding [GO:0008134]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular detoxification [GO:1990748]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan metabolic process [GO:0030212]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular detoxification [GO:1990748]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan metabolic process [GO:0030212]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; manganese ion binding [GO:0030145]; protein serine/threonine kinase activity [GO:0004674]; ribosomal small subunit binding [GO:0043024]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d2xj6a__d6coxa1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	chloroplast [GO:0009507]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d2xj8a1_d4nvnb___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2xjka__d1srda___1	Metazoa	Viridiplantae	Chordata	Streptophyta	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	chloroplast [GO:0009507]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chloroplast [GO:0009507]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2xjma__d1f30g___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2xjma__d1fz4a___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2xjmc__d3oj5b___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d2xjmd__d3e1mi___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2xjme__d1o9ra___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2xjmi__d2jd6m___1			Firmicutes	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d2xjmk__d1fz2d___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2xjml__d2vxxa___1			Firmicutes	Cyanobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2xjna__d4m1hd1__1			Firmicutes	Chlamydiae	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2xjnb__d2y3qe___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2xjnc__d2fjcb___1			Firmicutes	Spirochaetes	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2xjnd__d4zjka___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2xjne__d3h7ga___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2xjnh__d2z6me___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2xjnh__d4gaml___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2xjnj__d2z90b___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2xjnk__d1eumf___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cellular iron ion homeostasis [GO:0006879]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2xjnk__d2x17k___1			Firmicutes	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d2xjnl__d4bmua___1			Firmicutes	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2xjnl__d5d8xc___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2xjob__d3n1yb___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d2xjob__d4mn9a___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2xjoc__d5u1bh___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; efflux transmembrane transporter activity [GO:0015562]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	efflux transmembrane transporter activity [GO:0015562]
d2xjod__d4cyba___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2xjof__d3qd8u1__1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2xjoj__d2bkcp___1			Firmicutes	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2xjol__d2yjjd___1			Firmicutes	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d2xjwa__d112la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2xjwa__d2ihla___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2xk5b__d5hpld1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]	protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d2xkha__d4twva___1	Metazoa	Metazoa	Nemertea (ribbon worms)	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2xkia__d4f6ba___1	Metazoa	Metazoa	Nemertea (ribbon worms)	Nemertea (ribbon worms)	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2xkna2_d5dqjb1__1												
d2xkqb__d5ls9b___1			Firmicutes	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]
d2xkqc__d3pw1b1__1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cellular iron ion homeostasis [GO:0006879]	phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytosol [GO:0005829]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	
d2xkqf__d5c6fc1__1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d2xkqf__d5k53b___1			Firmicutes	Cyanobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]
d2xkqk__d1fz5b___1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2xkqk__d5c6fd1__1			Firmicutes	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d2xkra__d3zbya1__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; cholesterol 26-hydroxylase activity [GO:0031073]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; cholesterol catabolic process [GO:0006707]	cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]	cholesterol catabolic process [GO:0006707]	cell wall [GO:0005618]		cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; cholesterol 26-hydroxylase activity [GO:0031073]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2xkra__d5edta___1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; cholesterol 26-hydroxylase activity [GO:0031073]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]		cell wall [GO:0005618]	cytoplasm [GO:0005737]	cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; cholesterol 26-hydroxylase activity [GO:0031073]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2xkua1_d1nldh1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2xl6a__d5jp7a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2xlbb__d1hkha___1			Firmicutes	Actinobacteria	acetylesterase activity [GO:0008126]	peroxidase activity [GO:0004601]					acetylesterase activity [GO:0008126]	peroxidase activity [GO:0004601]
d2xlbc__d1ya4c1__1		Metazoa	Firmicutes	Chordata	acetylesterase activity [GO:0008126]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	acetylesterase activity [GO:0008126]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d2xlbc__d3fvtm___1			Firmicutes	Firmicutes	acetylesterase activity [GO:0008126]	acetylesterase activity [GO:0008126]					acetylesterase activity [GO:0008126]	acetylesterase activity [GO:0008126]
d2xlbd__d3head___1			Firmicutes	Proteobacteria	acetylesterase activity [GO:0008126]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]					acetylesterase activity [GO:0008126]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]
d2xlbe__d1tccb___1		Fungi	Firmicutes	Basidiomycota	acetylesterase activity [GO:0008126]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]			acetylesterase activity [GO:0008126]	triglyceride lipase activity [GO:0004806]
d2xlbh__d3wwpm1__1		Viridiplantae	Firmicutes	Streptophyta	acetylesterase activity [GO:0008126]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]					acetylesterase activity [GO:0008126]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]
d2xlbi__d3fvrm___1			Firmicutes	Firmicutes	acetylesterase activity [GO:0008126]	acetylesterase activity [GO:0008126]					acetylesterase activity [GO:0008126]	acetylesterase activity [GO:0008126]
d2xlbj__d3kdaa1__1			Firmicutes	Proteobacteria	acetylesterase activity [GO:0008126]	hydrolase activity [GO:0016787]					acetylesterase activity [GO:0008126]	hydrolase activity [GO:0016787]
d2xlwa__d3c62a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2xm4a__d2j8wb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2xmba__d1h2ya2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]		blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d2xmca__d1xfdb2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]; potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]	potassium channel regulator activity [GO:0015459]; serine-type peptidase activity [GO:0008236]
d2xmda__d2qt9b2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d2xmga__d1o6fa2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]		blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d2xmkb__d5f0wd___1		Metazoa	Cyanobacteria	Chordata	copper ion binding [GO:0005507]; metal ion transport [GO:0030001]	cell [GO:0005623]; cytosol [GO:0005829]; ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper ion binding [GO:0005507]; copper-dependent protein binding [GO:0032767]; metallochaperone activity [GO:0016530]; cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	metal ion transport [GO:0030001]	cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytosol [GO:0005829]	copper ion binding [GO:0005507]	ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; metallochaperone activity [GO:0016530]
d2xmta__d2ew9a2__1		Metazoa	Cyanobacteria	Chordata	copper ion binding [GO:0005507]; metal ion transport [GO:0030001]	cell [GO:0005623]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; protein maturation by copper ion transfer [GO:0015680]; response to copper ion [GO:0046688]; sequestering of calcium ion [GO:0051208]	metal ion transport [GO:0030001]	cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; protein maturation by copper ion transfer [GO:0015680]; response to copper ion [GO:0046688]; sequestering of calcium ion [GO:0051208]		cell [GO:0005623]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; membrane [GO:0016020]; mitochondrion [GO:0005739]; perinuclear region of cytoplasm [GO:0048471]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]	copper ion binding [GO:0005507]	ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]
d2xmvd__d1s6oa1__1		Metazoa	Cyanobacteria	Chordata	copper ion binding [GO:0005507]; metal ion transport [GO:0030001]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]; antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	metal ion transport [GO:0030001]	antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]		apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	copper ion binding [GO:0005507]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]
d2xnaa1_d2fl5l1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2xnab1_d1fnea1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2xnca1_d1ogja1__1	Viridiplantae		Streptophyta	Cyanobacteria	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d2xnca2_d1gjra2__1	Viridiplantae		Streptophyta	Cyanobacteria	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d2xncb2_d3qfta2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	photosynthesis [GO:0015979]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d2xnja1_d1gjra1__1			Proteobacteria	Cyanobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; FAD binding [GO:0071949]; ferredoxin-NADP+ reductase activity [GO:0004324]; oxidoreductase activity [GO:0016491]; fructose catabolic process [GO:0006001]; iron-sulfur cluster assembly [GO:0016226]; response to drug [GO:0042493]; response to superoxide [GO:0000303]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	fructose catabolic process [GO:0006001]; iron-sulfur cluster assembly [GO:0016226]; response to drug [GO:0042493]; response to superoxide [GO:0000303]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	phycobilisome [GO:0030089]	FAD binding [GO:0071949]; ferredoxin-NADP+ reductase activity [GO:0004324]; oxidoreductase activity [GO:0016491]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d2xnub__d2ymdc___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2xnub__d5ouhe___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d2xnuc__d2byrb1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2xnuc__d3sq9a___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d2xnud__d3wtlc1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2xnue__d3sq9d___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d2xnvc__d5afnc___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2xnve__d3wthc1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2xnvh__d1ux2d___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2xoke1_d5hkkm1__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2xokf3_d5ik2m3__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2xp3a2_d1bl4a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]
d2xp3a2_d4jysa___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]		beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2xp4a2_d5htgb___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cytoplasm [GO:0005737]; fungal biofilm matrix [GO:0062040]; drug binding [GO:0008144]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; cellular response to drug [GO:0035690]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cellular response to drug [GO:0035690]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	cytoplasm [GO:0005737]; fungal biofilm matrix [GO:0062040]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	drug binding [GO:0008144]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2xp6a2_d4w9pa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2xp7a2_d4drqa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2xpaa2_d4dipa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	endoplasmic reticulum lumen [GO:0005788]; calcium ion binding [GO:0005509]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; IRE1-mediated unfolded protein response [GO:0036498]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	IRE1-mediated unfolded protein response [GO:0036498]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	endoplasmic reticulum lumen [GO:0005788]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	calcium ion binding [GO:0005509]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2xpba2_d1a7xa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]
d2xpca3_d4hv4a3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]	ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]
d2xpdc1_d4gtuc2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; long-chain fatty acid biosynthetic process [GO:0042759]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; long-chain fatty acid biosynthetic process [GO:0042759]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	thioredoxin peroxidase activity [GO:0008379]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d2xpdd__d4fh8h1__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	thioredoxin peroxidase activity [GO:0008379]	peroxiredoxin activity [GO:0051920]
d2xpde__d4mabc___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]	thioredoxin peroxidase activity [GO:0008379]	thioredoxin peroxidase activity [GO:0008379]
d2xpeb__d3tkrd___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	thioredoxin peroxidase activity [GO:0008379]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d2xpgb1_d3vxtb1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2xphb__d2bzpa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; SUMO-specific isopeptidase activity [GO:0070140]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; proteolysis [GO:0006508]; regulation of definitive erythrocyte differentiation [GO:0010724]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; proteolysis [GO:0006508]; regulation of definitive erythrocyte differentiation [GO:0010724]		cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		endopeptidase activity [GO:0004175]; SUMO-specific isopeptidase activity [GO:0070140]	
d2xpka2_d3l4ua2__1		Metazoa	Firmicutes	Chordata	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]		apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]
d2xpka3_d2jiwb1__1			Firmicutes	Bacteroidetes	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]			[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]
d2xpwa2_d3btie2__1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2xqga__d3og9b___1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	hydrolase activity [GO:0016787]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]		blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]		acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]	hydrolase activity [GO:0016787]
d2xqka__d4htaa1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	cytosol [GO:0005829]; nucleus [GO:0005634]; hydrolase activity [GO:0016787]; de-etiolation [GO:0009704]; photomorphogenesis [GO:0009640]; response to karrikin [GO:0080167]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	de-etiolation [GO:0009704]; photomorphogenesis [GO:0009640]; response to karrikin [GO:0080167]	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	cytosol [GO:0005829]; nucleus [GO:0005634]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]	hydrolase activity [GO:0016787]
d2xqnm1_d4hhvb___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; Golgi apparatus [GO:0005794]; male germ cell nucleus [GO:0001673]; motile cilium [GO:0031514]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; structural constituent of cytoskeleton [GO:0005200]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ceramide 1-phosphate binding [GO:1902387]; ceramide 1-phosphate transfer activity [GO:1902388]; ceramide binding [GO:0097001]; ceramide transfer activity [GO:0120017]; kinase activity [GO:0016301]; lipid binding [GO:0008289]; phosphatidylinositol-4-phosphate binding [GO:0070273]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; ceramide metabolic process [GO:0006672]; ceramide transport [GO:0035627]; endoplasmic reticulum organization [GO:0007029]; ER to Golgi ceramide transport [GO:0035621]; heart morphogenesis [GO:0003007]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; intermembrane lipid transfer [GO:0120009]; intermembrane sphingolipid transfer [GO:0120012]; lipid homeostasis [GO:0055088]; mitochondrion morphogenesis [GO:0070584]; muscle contraction [GO:0006936]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; sphingolipid biosynthetic process [GO:0030148]		cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; ceramide metabolic process [GO:0006672]; ceramide transport [GO:0035627]; endoplasmic reticulum organization [GO:0007029]; ER to Golgi ceramide transport [GO:0035621]; heart morphogenesis [GO:0003007]; immune response [GO:0006955]; intermembrane lipid transfer [GO:0120009]; intermembrane sphingolipid transfer [GO:0120012]; in utero embryonic development [GO:0001701]; lipid homeostasis [GO:0055088]; mitochondrion morphogenesis [GO:0070584]; muscle contraction [GO:0006936]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; sphingolipid biosynthetic process [GO:0030148]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; Golgi apparatus [GO:0005794]; male germ cell nucleus [GO:0001673]; motile cilium [GO:0031514]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	structural constituent of cytoskeleton [GO:0005200]	ceramide 1-phosphate binding [GO:1902387]; ceramide 1-phosphate transfer activity [GO:1902388]; ceramide binding [GO:0097001]; ceramide transfer activity [GO:0120017]; kinase activity [GO:0016301]; lipid binding [GO:0008289]; phosphatidylinositol-4-phosphate binding [GO:0070273]
d2xqwb1_d1ft1b___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d2xqyk2_d4y5ve___1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; fusion of virus membrane with host plasma membrane [GO:0019064]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	fusion of virus membrane with host plasma membrane [GO:0019064]	brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]		erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]
d2xqyl1_d2xtjb___1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; fusion of virus membrane with host plasma membrane [GO:0019064]	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor recycling [GO:0001920]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	fusion of virus membrane with host plasma membrane [GO:0019064]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of receptor recycling [GO:0001920]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]		apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]
d2xqyl2_d3aveb2__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; fusion of virus membrane with host plasma membrane [GO:0019064]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	fusion of virus membrane with host plasma membrane [GO:0019064]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2xr4b1_d1ovsd___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]		single-species biofilm formation [GO:0044010]			identical protein binding [GO:0042802]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2xr4b1_d4aoca___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]	metal ion binding [GO:0046872]					identical protein binding [GO:0042802]	metal ion binding [GO:0046872]
d2xr6a__d2yhfe___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]; cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]	carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]
d2xr8a2_d4c9ia1__1		Viridiplantae	Proteobacteria	Streptophyta	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid binding [GO:0010427]; flavonoid binding [GO:0097243]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]			biphenyl 2,3-dioxygenase activity [GO:0018687]	abscisic acid binding [GO:0010427]; flavonoid binding [GO:0097243]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2xr8d__d6stdc1__1		Fungi	Proteobacteria	Ascomycota	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	endosome [GO:0005768]; metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]; melanin biosynthetic process [GO:0042438]	aromatic compound catabolic process [GO:0019439]	melanin biosynthetic process [GO:0042438]		endosome [GO:0005768]	biphenyl 2,3-dioxygenase activity [GO:0018687]	metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]
d2xr8e2_d4hkva2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d2xr8g2_d4a8va___1		Viridiplantae	Proteobacteria	Streptophyta	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]	biphenyl 2,3-dioxygenase activity [GO:0018687]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2xr8k2_d2l65a1__1			Proteobacteria	Actinobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]	
d2xr8k2_d4n3ez___1		Viridiplantae	Proteobacteria	Streptophyta	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]			biphenyl 2,3-dioxygenase activity [GO:0018687]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2xr8m2_d2ktea1__1			Proteobacteria	Firmicutes	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]	
d2xr8o2_d2yflk2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2xr8q2_d4a85a___1		Viridiplantae	Proteobacteria	Streptophyta	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]	biphenyl 2,3-dioxygenase activity [GO:0018687]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2xr8r__d1ulid___1			Proteobacteria	Actinobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2xr8s2_d2xsos2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2xr8u2_d3c0va___1		Viridiplantae	Proteobacteria	Streptophyta	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]			biphenyl 2,3-dioxygenase activity [GO:0018687]	abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2xr8x__d2geyc2__1			Proteobacteria	Actinobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	polyketide metabolic process [GO:0030638]	aromatic compound catabolic process [GO:0019439]	polyketide metabolic process [GO:0030638]			biphenyl 2,3-dioxygenase activity [GO:0018687]	
d2xrea__d3kvfa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; SUMO-specific isopeptidase activity [GO:0070140]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; proteolysis [GO:0006508]; regulation of definitive erythrocyte differentiation [GO:0010724]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; adult walking behavior [GO:0007628]; axon target recognition [GO:0007412]; axonal transport of mitochondrion [GO:0019896]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; proteolysis [GO:0006508]; regulation of definitive erythrocyte differentiation [GO:0010724]	adult walking behavior [GO:0007628]; axonal transport of mitochondrion [GO:0019896]; axon target recognition [GO:0007412]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]	cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]	endopeptidase activity [GO:0004175]; SUMO-specific isopeptidase activity [GO:0070140]	alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]
d2xrma__d1yu6a___1		Metazoa	Firmicutes	Chordata	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]				extracellular region [GO:0005576]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase inhibitor activity [GO:0004867]
d2xrqf__d2aq3b1__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]	extracellular region [GO:0005576]	T cell receptor complex [GO:0042101]	toxin activity [GO:0090729]	
d2xrsd__d2rdga1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	
d2xrsf__d1ts5a1__1			Proteobacteria	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d2xrsf__d2nzgm___1			Proteobacteria		extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]		killing of cells of other organism [GO:0031640]		extracellular region [GO:0005576]		toxin activity [GO:0090729]	
d2xrsl__d1bosb___1			Proteobacteria		extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	killing of cells of other organism [GO:0031640]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d2xrxa2_d1txcb2__1		Viridiplantae	Proteobacteria	Streptophyta	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]			biphenyl 2,3-dioxygenase activity [GO:0018687]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2xrxb__d2geya1__1			Proteobacteria	Actinobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	polyketide metabolic process [GO:0030638]	aromatic compound catabolic process [GO:0019439]	polyketide metabolic process [GO:0030638]			biphenyl 2,3-dioxygenase activity [GO:0018687]	
d2xrxc2_d4c94a1__1		Viridiplantae	Proteobacteria	Streptophyta	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]			biphenyl 2,3-dioxygenase activity [GO:0018687]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2xrxh__d1a2kb___1		Metazoa	Proteobacteria	Chordata	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	aromatic compound catabolic process [GO:0019439]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]		cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	biphenyl 2,3-dioxygenase activity [GO:0018687]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]
d2xrxi2_d1o7ma2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d2xrxi2_d3gzya2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2xrxk2_d2b24e2__1			Proteobacteria	Actinobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]			biphenyl 2,3-dioxygenase activity [GO:0018687]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]
d2xrxn__d2b24d___1			Proteobacteria	Actinobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	aromatic compound catabolic process [GO:0019439]	cellular metabolic process [GO:0044237]			biphenyl 2,3-dioxygenase activity [GO:0018687]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]
d2xrxu2_d4hm2a2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d2xrxw2_d4ma6a___1		Viridiplantae	Proteobacteria	Streptophyta	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]			biphenyl 2,3-dioxygenase activity [GO:0018687]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2xscd__d2ntsa1__1		Metazoa		Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	toxin activity [GO:0090729]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2xsfa__d4ckoa3__1	Metazoa		Chordata		cytoplasm [GO:0005737]; nucleus [GO:0005634]; polysome [GO:0005844]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; mRNA 3'-UTR binding [GO:0003730]; translation activator activity [GO:0008494]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; female meiosis II [GO:0007147]; germ cell development [GO:0007281]; multicellular organism development [GO:0007275]; oocyte maturation [GO:0001556]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of translational initiation [GO:0045948]; spermatogenesis [GO:0007283]		3'-UTR-mediated mRNA stabilization [GO:0070935]; female meiosis II [GO:0007147]; germ cell development [GO:0007281]; multicellular organism development [GO:0007275]; oocyte maturation [GO:0001556]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of translational initiation [GO:0045948]; spermatogenesis [GO:0007283]		cytoplasm [GO:0005737]; nucleus [GO:0005634]; polysome [GO:0005844]; protein-containing complex [GO:0032991]		identical protein binding [GO:0042802]; mRNA 3'-UTR binding [GO:0003730]; translation activator activity [GO:0008494]	
d2xshc2_d1txca2__1		Viridiplantae	Proteobacteria	Streptophyta	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]			biphenyl 2,3-dioxygenase activity [GO:0018687]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2xshd__d1ohsd___1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	aromatic compound catabolic process [GO:0019439]	steroid metabolic process [GO:0008202]			biphenyl 2,3-dioxygenase activity [GO:0018687]	steroid delta-isomerase activity [GO:0004769]
d2xshe2_d2de6b2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]	aromatic compound catabolic process [GO:0019439]	carbazole catabolic process [GO:0046232]			biphenyl 2,3-dioxygenase activity [GO:0018687]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]
d2xshf__d4nhfa___1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; protein secretion by the type IV secretion system [GO:0030255]	aromatic compound catabolic process [GO:0019439]	protein secretion by the type IV secretion system [GO:0030255]		integral component of membrane [GO:0016021]	biphenyl 2,3-dioxygenase activity [GO:0018687]	metal ion binding [GO:0046872]
d2xshi2_d4hm7a2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d2xshl__d5wiid___1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; protein secretion by the type IV secretion system [GO:0030255]	aromatic compound catabolic process [GO:0019439]	protein secretion by the type IV secretion system [GO:0030255]		integral component of membrane [GO:0016021]	biphenyl 2,3-dioxygenase activity [GO:0018687]	
d2xsia2_d2xw1b3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2xsia3_d4l9qa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2xsjf__d1saua___1			Proteobacteria	Euryarchaeota	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]						4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	
d2xsoa2_d1llta___1		Viridiplantae	Proteobacteria	Streptophyta	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]	biphenyl 2,3-dioxygenase activity [GO:0018687]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2xsoc2_d1e09a___1		Viridiplantae	Proteobacteria	Streptophyta	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]			biphenyl 2,3-dioxygenase activity [GO:0018687]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2xsod__d1mwxa4__1			Proteobacteria		biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]	
d2xsof__d4hjlb___1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d2xsof__d5ig4g___1		Metazoa	Proteobacteria	Cnidaria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]	aromatic compound catabolic process [GO:0019439]			cytoplasm [GO:0005737]; neuron projection [GO:0043005]	biphenyl 2,3-dioxygenase activity [GO:0018687]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]
d2xsog2_d4gy9a1__1		Viridiplantae	Proteobacteria	Streptophyta	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; cytokinin-activated signaling pathway [GO:0009736]; defense response [GO:0006952]; nodulation [GO:0009877]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; cytokinin-activated signaling pathway [GO:0009736]; defense response [GO:0006952]; nodulation [GO:0009877]; response to biotic stimulus [GO:0009607]			biphenyl 2,3-dioxygenase activity [GO:0018687]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2xsog2_d4hm5a2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d2xsoh__d4lsoa___1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; pathogenesis [GO:0009405]; protein secretion by the type IV secretion system [GO:0030255]	aromatic compound catabolic process [GO:0019439]	pathogenesis [GO:0009405]; protein secretion by the type IV secretion system [GO:0030255]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	biphenyl 2,3-dioxygenase activity [GO:0018687]	
d2xsok2_d1o7ga2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d2xsol__d1eg9b___1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d2xsom2_d2yfla2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2xsoo2_d1kcma___1		Metazoa	Proteobacteria	Chordata	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; myelin sheath [GO:0043209]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]; phosphatidylcholine binding [GO:0031210]; phosphatidylcholine transporter activity [GO:0008525]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol transfer activity [GO:0008526]; phospholipid binding [GO:0005543]; stearic acid binding [GO:0070540]; axonogenesis [GO:0007409]; phospholipid transport [GO:0015914]	aromatic compound catabolic process [GO:0019439]	axonogenesis [GO:0007409]; phospholipid transport [GO:0015914]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of membrane [GO:0016021]; myelin sheath [GO:0043209]	biphenyl 2,3-dioxygenase activity [GO:0018687]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]; phosphatidylcholine binding [GO:0031210]; phosphatidylcholine transporter activity [GO:0008525]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol transfer activity [GO:0008526]; phospholipid binding [GO:0005543]; stearic acid binding [GO:0070540]
d2xsox__d1mwsa1__1			Proteobacteria	Firmicutes	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; response to antibiotic [GO:0046677]	aromatic compound catabolic process [GO:0019439]	response to antibiotic [GO:0046677]		integral component of membrane [GO:0016021]	biphenyl 2,3-dioxygenase activity [GO:0018687]	penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]
d2xt0a__d3fvth___1			Proteobacteria	Firmicutes	catalytic activity [GO:0003824]	acetylesterase activity [GO:0008126]					catalytic activity [GO:0003824]	acetylesterase activity [GO:0008126]
d2xtha__d3d3db___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lyase activity [GO:0016829]; lysozyme activity [GO:0003796]; lytic transglycosylase activity [GO:0008933]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lyase activity [GO:0016829]; lysozyme activity [GO:0003796]; lytic transglycosylase activity [GO:0008933]
d2xtjb__d1zlwh1__1	Metazoa		Chordata		cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor recycling [GO:0001920]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]		apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of receptor recycling [GO:0001920]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]		cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]		apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]	
d2xtjc__d5b6fe1__1	Metazoa		Chordata		cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor recycling [GO:0001920]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]		apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of receptor recycling [GO:0001920]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]		cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]		apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]	
d2xtka1_d1cxfa4__1	Fungi		Ascomycota	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2xtka1_d4lx4b___1	Fungi		Ascomycota	Proteobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2xu3a__d1ayua___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; histone binding [GO:0042393]; proteoglycan binding [GO:0043394]; serpin family protein binding [GO:0097655]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; macrophage apoptotic process [GO:0071888]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; macrophage apoptotic process [GO:0071888]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; histone binding [GO:0042393]; proteoglycan binding [GO:0043394]; serpin family protein binding [GO:0097655]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d2xuca1_d3f5la___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	anchored component of membrane [GO:0031225]; cell wall [GO:0005618]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	anchored component of membrane [GO:0031225]; cell wall [GO:0005618]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d2xura1_d1iz5b1__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]		3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d2xura2_d2ntih1__1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	PCNA complex [GO:0043626]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d2xurb2_d2ix2c1__1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	PCNA complex [GO:0043626]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d2xurb3_d2xurb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d2xv0a__d1mdab___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2xv1a1_d3k1ab___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	nitrogen fixation [GO:0009399]	cytoplasm [GO:0005737]; outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2xv3b__d4knta2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2xvmb__d5c1ib___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; response to antibiotic [GO:0046677]; response to tellurium ion [GO:0046690]; response to toxic substance [GO:0009636]	tRNA (m1A) methyltransferase complex [GO:0031515]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]; tRNA methylation [GO:0030488]	response to antibiotic [GO:0046677]; response to tellurium ion [GO:0046690]; response to toxic substance [GO:0009636]	tRNA methylation [GO:0030488]	cytosol [GO:0005829]	tRNA (m1A) methyltransferase complex [GO:0031515]	S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]
d2xvnb__d5juva1__1	Fungi	Fungi	Ascomycota	Ascomycota	anchored component of membrane [GO:0031225]; cell wall [GO:0005618]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]; carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	anchored component of membrane [GO:0031225]; cell wall [GO:0005618]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]
d2xvpa1_d1dwgm___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		vacuole [GO:0005773]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]
d2xvva2_d2xsia3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2xvwa3_d1bm0b1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2xvya__d4f4da___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; cobalt ion binding [GO:0050897]; heme binding [GO:0020037]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; sirohydrochlorin ferrochelatase activity [GO:0051266]; anaerobic cobalamin biosynthetic process [GO:0019251]; protein tetramerization [GO:0051262]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	anaerobic cobalamin biosynthetic process [GO:0019251]; protein tetramerization [GO:0051262]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	periplasmic space [GO:0042597]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cobalt ion binding [GO:0050897]; heme binding [GO:0020037]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; sirohydrochlorin ferrochelatase activity [GO:0051266]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d2xw1b2_d4g03a3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2xw1b2_d5iiha1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2xw2b__d3spta1__1				Actinobacteria		cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]; adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]
d2xw4b__d1g1lf___1				Proteobacteria		glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]				glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2xw6a1_d1c3og2__1			Deinococcus-Thermus	Proteobacteria	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]		carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2xw6b1_d1oz0a1__1		Metazoa	Deinococcus-Thermus	Chordata	methylglyoxal synthase activity [GO:0008929]; methylglyoxal biosynthetic process [GO:0019242]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	methylglyoxal biosynthetic process [GO:0019242]	'de novo' IMP biosynthetic process [GO:0006189]		cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d2xwaa__d4ausa1__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]		complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]		serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	
d2xwaa__d5gch.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; neutrophil degranulation [GO:0043312]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; proteolysis [GO:0006508]	digestion [GO:0007586]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; platelet alpha granule lumen [GO:0031093]; secretory granule lumen [GO:0034774]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2xwla1_d1fgxb___1		Metazoa	Actinobacteria	Chordata	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [GO:0050518]; nucleotide binding [GO:0000166]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [GO:0050518]; nucleotide binding [GO:0000166]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d2xwma1_d4eema___1		Metazoa	Actinobacteria	Chordata	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [GO:0050518]; nucleotide binding [GO:0000166]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [GO:0050518]; nucleotide binding [GO:0000166]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d2xwpa__d3aqia___1		Metazoa	Proteobacteria	Chordata	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]; anaerobic cobalamin biosynthetic process [GO:0019251]; porphyrin-containing compound biosynthetic process [GO:0006779]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	anaerobic cobalamin biosynthetic process [GO:0019251]; porphyrin-containing compound biosynthetic process [GO:0006779]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d2xwqd__d3hcpa___1		Metazoa	Euryarchaeota	Chordata	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]; anaerobic cobalamin biosynthetic process [GO:0019251]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	anaerobic cobalamin biosynthetic process [GO:0019251]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d2xwsa1_d4klcb___1		Metazoa	Euryarchaeota	Chordata	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]; anaerobic cobalamin biosynthetic process [GO:0019251]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	anaerobic cobalamin biosynthetic process [GO:0019251]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d2xwtb1_d1dbml2__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]; activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2xwtb2_d3dvnh1__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]; activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2xwua__d1jbba___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]; ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin conjugating enzyme complex [GO:0031371]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; free ubiquitin chain polymerization [GO:0010994]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	free ubiquitin chain polymerization [GO:0010994]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin conjugating enzyme complex [GO:0031371]	ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]
d2xwva1_d2q2aa___1			Proteobacteria	Firmicutes	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]		outer membrane-bounded periplasmic space [GO:0030288]	membrane [GO:0016020]		ligand-gated ion channel activity [GO:0015276]
d2xwzc1_d2ve0a1__1			Proteobacteria		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	
d2xwzc2_d3t6za3__1		Fungi	Proteobacteria	Basidiomycota	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	nitrogen compound metabolic process [GO:0006807]				copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2xwzd1_d3fu7b1__1		Fungi	Proteobacteria	Ascomycota	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	nitrogen compound metabolic process [GO:0006807]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2xwzd2_d1pnca___1		Viridiplantae	Proteobacteria	Streptophyta	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	nitrogen compound metabolic process [GO:0006807]			chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2xwze2_d1ziba___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	nitrogen compound metabolic process [GO:0006807]			periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2xwze2_d2x87a2__1			Proteobacteria	Firmicutes	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	nitrogen compound metabolic process [GO:0006807]	sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2xwzf1_d1pf3a2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	nitrogen compound metabolic process [GO:0006807]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d2xx0a2_d1j9sb2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2xx0a2_d2jxma___1			Proteobacteria	Cyanobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	integral component of thylakoid membrane [GO:0031361]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	nitrogen compound metabolic process [GO:0006807]	photosynthesis [GO:0015979]		integral component of thylakoid membrane [GO:0031361]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2xx0b1_d2pp9b2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2xx0b2_d2qt6b3__1		Fungi	Proteobacteria	Basidiomycota	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	nitrogen compound metabolic process [GO:0006807]				copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d2xx1b1_d1fwxa1__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]		membrane [GO:0016020]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d2xx1b2_d1ag0b___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2xx1c2_d9pcya___1		Viridiplantae	Proteobacteria	Streptophyta	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	nitrogen compound metabolic process [GO:0006807]			chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2xx1d1_d1a4aa___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	nitrogen compound metabolic process [GO:0006807]			periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2xx1d2_d3in0a___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2xx1e2_d1as7c2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2xx2d__d5d7db___1	Fungi		Ascomycota	Firmicutes	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d2xx7a1_d2voza___1	Metazoa		Chordata	Cyanobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; thylakoid membrane [GO:0042651]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]; thylakoid membrane [GO:0042651]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	metal ion binding [GO:0046872]
d2xx7b1_d3h03g___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2xx9a1_d4l17e___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2xxea1_d2hsdb___1				Actinobacteria		androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; C21-steroid hormone metabolic process [GO:0008207]		C21-steroid hormone metabolic process [GO:0008207]				androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]
d2xxea2_d1y7tb2__1				Deinococcus-Thermus		L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]				L-malate dehydrogenase activity [GO:0030060]
d2xxeb2_d3gvic2__1				Proteobacteria		L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]				L-malate dehydrogenase activity [GO:0030060]
d2xxec2_d4i9nd2__1		Metazoa		Chordata		cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]
d2xxfa2_d1rkrd___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	nitrogen compound metabolic process [GO:0006807]			periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2xxfb1_d1ilsa___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2xxga2_d1uvwa6__1			Proteobacteria		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	
d2xxga2_d2yxva2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	nitrogen compound metabolic process [GO:0006807]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d2xxgc2_d1ilul___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2xxhc__d1s9tb___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d2xxhc__d3e13x___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	metal ion binding [GO:0046872]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	metal ion binding [GO:0046872]
d2xxjb2_d3pqdh2__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d2xxjc2_d1ltht2__1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d2xxjc2_d3nepx2__1			Deinococcus-Thermus	Bacteroidetes	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]
d2xxka1_d3wafb___1			Proteobacteria	Deinococcus-Thermus	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	metal ion binding [GO:0046872]	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]		outer membrane-bounded periplasmic space [GO:0030288]			metal ion binding [GO:0046872]
d2xxra__d5on0b___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]
d2xxrb__d2qs4d___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d2xxta__d3m3ka___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2xxtb__d3rnnc___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2xxua__d1b2ha___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	protein transport [GO:0015031]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	peptide transmembrane transporter activity [GO:1904680]
d2xxua__d4rpob___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; aromatic compound catabolic process [GO:0019439]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	aromatic compound catabolic process [GO:0019439]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]		extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2xxva__d5on9a___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]
d2xxvb__d4gxsb___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2xxwa__d1tfaa___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]
d2xxwb__d4jkmd1__1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d2xxxc__d1ovta2__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]; ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]; acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	acute-phase response [GO:0006953]; antimicrobial humoral response [GO:0019730]; extracellular sequestering of iron ion [GO:0006881]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	cell [GO:0005623]; extracellular space [GO:0005615]; organomineral extracellular matrix [GO:1990377]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	ferric iron binding [GO:0008199]; iron ion binding [GO:0005506]
d2xxya__d1quja___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	phosphate ion binding [GO:0042301]
d2xy2a1_d4n1cb___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; integral component of membrane [GO:0016021]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; axonal fasciculation [GO:0007413]; neuron cell-cell adhesion [GO:0007158]; sensory perception of smell [GO:0007608]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	axonal fasciculation [GO:0007413]; neuron cell-cell adhesion [GO:0007158]; sensory perception of smell [GO:0007608]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	axon [GO:0030424]; integral component of membrane [GO:0016021]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2xy3d__d4apzt___1			Firmicutes	Firmicutes	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d2xyba2_d1e30b___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2xyba3_d5n8ga2__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2xyeb__d1k6pa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2xyfb__d5p4xa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2xykb__d1hgaa___1		Metazoa	Proteobacteria	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2xyla__d1e73m___1		Viridiplantae	Actinobacteria	Streptophyta	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]		vacuole [GO:0005773]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]
d2xysc__d4xhee1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2xysd__d4qacf1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2xysd__d5lxbc___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2xyse__d5ougc___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d2xytb__d2ph9b1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2xytd__d1uw6i___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2xyth__d5afna___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2xz6b__d3sq9g___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d2xz6c__d1i9bc1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2xz6h__d1uw6c___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2xzcl2_d1jvka1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2xzwc1_d3ncqb___1			Cyanobacteria	Euryarchaeota	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; regulation of nitrogen utilization [GO:0006808]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]	regulation of nitrogen utilization [GO:0006808]	regulation of nitrogen utilization [GO:0006808]			enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]
d2xzwh__d1naqa___1			Cyanobacteria	Proteobacteria	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; regulation of nitrogen utilization [GO:0006808]	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; metal ion binding [GO:0046872]; protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	regulation of nitrogen utilization [GO:0006808]	protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]		cytoplasm [GO:0005737]	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	copper ion binding [GO:0005507]; metal ion binding [GO:0046872]
d2y0ja__d5u7ka1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d2y0jb__d5tzab1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d2y1aa1_d5ue6f1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2y24a2_d3baka2__1		Metazoa	Proteobacteria	Chordata	glucosylceramidase activity [GO:0004348]; sphingolipid metabolic process [GO:0006665]; xylan catabolic process [GO:0045493]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	sphingolipid metabolic process [GO:0006665]; xylan catabolic process [GO:0045493]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	glucosylceramidase activity [GO:0004348]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d2y2ba__d4fnnd___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]
d2y2bc__d3hmab___1			Proteobacteria		cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]		cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]		cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]	
d2y2da__d4oppb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]
d2y2eb__d3o4kb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]
d2y32a__d2zsca___1		Fungi	Proteobacteria	Basidiomycota	biotin binding [GO:0009374]	biotin binding [GO:0009374]					biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2y3fa__d1swta___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d2y3nc1_d5g5da___1			Firmicutes	Firmicutes	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cell wall organization [GO:0071555]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]; cell wall organization [GO:0071555]		extracellular region [GO:0005576]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2y3qc__d5e1ua___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2y3qd__d3ka6a___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2y3qf__d4cybl___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2y3qg__d1fz2c___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d2y3qj__d1l8hh___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2y3qk__d1f33l___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2y40b1_d1td9a___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	cytoplasm [GO:0005737]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	leucine biosynthetic process [GO:0009098]	acetyl-CoA biosynthetic process [GO:0006085]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	phosphate acetyltransferase activity [GO:0008959]
d2y42a1_d4zdad___1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]		3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]
d2y46b__d1pq2a___1		Metazoa	Actinobacteria	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]
d2y4ka__d4b5bb___1			Bacteroidetes	Proteobacteria		glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]				glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2y4la__d1gwwa___1		Metazoa	Bacteroidetes	Chordata		Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]		carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]		Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]		metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d2y4mb__d2bo8g___1			Bacteroidetes	Bacteroidetes		identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]; mannosylglycerate biosynthetic process [GO:0051479]		mannosylglycerate biosynthetic process [GO:0051479]				identical protein binding [GO:0042802]; mannosylglycerate synthase activity [GO:0102921]; metal ion binding [GO:0046872]; transferase activity, transferring hexosyl groups [GO:0016758]
d2y4wa__d5ojja___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; replication fork [GO:0005657]; XY body [GO:0001741]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular response to DNA damage stimulus [GO:0006974]; chiasma assembly [GO:0051026]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; histone H2A ubiquitination [GO:0033522]; histone lysine demethylation [GO:0070076]; in utero embryonic development [GO:0001701]; maintenance of chromatin silencing [GO:0006344]; meiotic telomere clustering [GO:0045141]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of histone phosphorylation [GO:0033128]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of reciprocal meiotic recombination [GO:0010845]; postreplication repair [GO:0006301]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; response to drug [GO:0042493]; response to UV [GO:0009411]; sperm axoneme assembly [GO:0007288]; spermatogenesis [GO:0007283]; synaptonemal complex organization [GO:0070193]; ubiquitin-dependent protein catabolic process [GO:0006511]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K6-linked ubiquitination [GO:0085020]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]	cellular response to DNA damage stimulus [GO:0006974]; chiasma assembly [GO:0051026]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; histone H2A ubiquitination [GO:0033522]; histone lysine demethylation [GO:0070076]; in utero embryonic development [GO:0001701]; maintenance of chromatin silencing [GO:0006344]; meiotic telomere clustering [GO:0045141]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of histone phosphorylation [GO:0033128]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of reciprocal meiotic recombination [GO:0010845]; postreplication repair [GO:0006301]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; response to drug [GO:0042493]; response to UV [GO:0009411]; spermatogenesis [GO:0007283]; sperm axoneme assembly [GO:0007288]; synaptonemal complex organization [GO:0070193]; ubiquitin-dependent protein catabolic process [GO:0006511]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]	cell [GO:0005623]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; replication fork [GO:0005657]; XY body [GO:0001741]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]
d2y4za1_d2pwmh___1					host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral budding via host ESCRT complex [GO:0039702]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral budding via host ESCRT complex [GO:0039702]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2y5aa1_d3vlia2__1	Fungi		Ascomycota	Euryarchaeota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2y5bb1_d4hcpb1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]		protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	
d2y5bf2_d2d07b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]
d2y5ca1_d2w3sc1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; C21-steroid hormone biosynthetic process [GO:0006700]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	C21-steroid hormone biosynthetic process [GO:0006700]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]		mitochondrial matrix [GO:0005759]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d2y5ha__d3zz3a1__1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2y5ic__d1n2db___1	Metazoa	Fungi	Chordata	Ascomycota	calcium ion binding [GO:0005509]	cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; MIH complex [GO:0120155]; myosin II complex [GO:0016460]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; myosin II heavy chain binding [GO:0032038]; myosin V binding [GO:0031489]; actomyosin contractile ring assembly [GO:0000915]; protein localization [GO:0008104]; vesicle targeting [GO:0006903]		actomyosin contractile ring assembly [GO:0000915]; protein localization [GO:0008104]; vesicle targeting [GO:0006903]		cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; MIH complex [GO:0120155]; myosin II complex [GO:0016460]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; myosin II heavy chain binding [GO:0032038]; myosin V binding [GO:0031489]
d2y5na__d2feub___1			Actinobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2y5za__d4ktka___1			Actinobacteria		heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]				heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	
d2y5zc__d2h7ra___1			Actinobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2y61a__d4o4wa___1					glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	glycosome [GO:0020015]	cytosol [GO:0005829]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2y62a__d3py2a___1				Apicomplexa	glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycosome [GO:0020015]		triose-phosphate isomerase activity [GO:0004807]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]
d2y63a__d4bi5l___1					glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycosome [GO:0020015]	cytoplasm [GO:0005737]	triose-phosphate isomerase activity [GO:0004807]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]
d2y69o2_d1nica1__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2y6aa__d1mnpa___1	Viridiplantae	Fungi	Streptophyta	Basidiomycota	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]	extracellular region [GO:0005576]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; manganese peroxidase activity [GO:0016689]; metal ion binding [GO:0046872]
d2y6ba__d5syxa2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]		heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2y6ka__d1jz4c3__1			Bacteroidetes	Proteobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2y6ka__d3jxsb___1			Bacteroidetes	Bacteroidetes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2y6pb__d2vs5b___1		Metazoa	Aquificae	Chordata	cytosol [GO:0005829]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide biosynthetic process [GO:0009103]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	cytosol [GO:0005829]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d2y6za1_d4nvta___1				Proteobacteria	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytoplasm [GO:0005737]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2y70b__d1lzod___1				Apicomplexa	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]		triose-phosphate isomerase activity [GO:0004807]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]
d2y70d__d2veib___1					cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2y70d__d4y9aa___1				Actinobacteria	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	cytosol [GO:0005829]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d2y7ia__d1p1wa___1		Metazoa	Proteobacteria	Chordata	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]; metal ion binding [GO:0046872]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	membrane [GO:0016020]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ligand-gated ion channel activity [GO:0015276]; metal ion binding [GO:0046872]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2y7ib__d1lbcb1__1		Metazoa	Proteobacteria	Chordata	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]; metal ion binding [GO:0046872]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	membrane [GO:0016020]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ligand-gated ion channel activity [GO:0015276]; metal ion binding [GO:0046872]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2y7ka__d2zzvb___1			Proteobacteria	Deinococcus-Thermus	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; lactate transport [GO:0015727]; transmembrane transport [GO:0055085]		lactate transport [GO:0015727]; transmembrane transport [GO:0055085]		periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]
d2y7kd__d1nnka___1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2y7kd__d1sd3b___1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]		behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]		axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d2y7pa1_d4yb6d1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]		histidine biosynthetic process [GO:0000105]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d2y7rb__d2al4f___1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2y7rb__d4o8mb___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	outer membrane-bounded periplasmic space [GO:0030288]; transmembrane transport [GO:0055085]		transmembrane transport [GO:0055085]		outer membrane-bounded periplasmic space [GO:0030288]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	
d2y7rf__d4r6ha___1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	plasma membrane [GO:0005886]; polysaccharide transport [GO:0015774]		polysaccharide transport [GO:0015774]		plasma membrane [GO:0005886]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	
d2y7rg__d1tt1b___1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]		behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]		axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d2y7rg__d3lsfb___1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2y7xa__d1c4u.1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d2y7ye__d1uw6b___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2y80a__d2k1qa1__1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2y81a__d1v2rt___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2y84a__d1blfa1__1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]		antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]		cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d2y84c__d3k6ua___1			Proteobacteria	Euryarchaeota	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	outer membrane-bounded periplasmic space [GO:0030288]; tungstate binding [GO:1901359]				outer membrane-bounded periplasmic space [GO:0030288]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	tungstate binding [GO:1901359]
d2y84d__d2dfzd___1			Proteobacteria		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]						DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	
d2y84e__d3mama___1			Proteobacteria	Euryarchaeota	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]				ATP-binding cassette (ABC) transporter complex [GO:0043190]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]
d2y84g__d5vijb___1		Metazoa	Proteobacteria	Chordata	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cell [GO:0005623]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; neuron projection [GO:0043005]; NMDA selective glutamate receptor complex [GO:0017146]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; ATPase binding [GO:0051117]; cell adhesion molecule binding [GO:0050839]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; glutamate receptor binding [GO:0035254]; glutamate-gated calcium ion channel activity [GO:0022849]; ionotropic glutamate receptor activity [GO:0004970]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; zinc ion binding [GO:0008270]; action potential [GO:0001508]; calcium ion transmembrane import into cytosol [GO:0097553]; cellular response to amino acid stimulus [GO:0071230]; cellular response to dsRNA [GO:0071359]; cellular response to growth factor stimulus [GO:0071363]; cellular response to lipid [GO:0071396]; cellular response to magnesium ion [GO:0071286]; cellular response to manganese ion [GO:0071287]; cellular response to zinc ion [GO:0071294]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; dendritic spine organization [GO:0097061]; excitatory postsynaptic potential [GO:0060079]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of cell death [GO:0010942]; positive regulation of excitatory postsynaptic potential [GO:2000463]; protein tetramerization [GO:0051262]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; response to amine [GO:0014075]; response to ammonium ion [GO:0060359]; response to calcium ion [GO:0051592]; response to carbohydrate [GO:0009743]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to fungicide [GO:0060992]; response to light stimulus [GO:0009416]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to organic cyclic compound [GO:0014070]; response to other organism [GO:0051707]; rhythmic process [GO:0048511]; spinal cord development [GO:0021510]; synaptic transmission, glutamatergic [GO:0035249]		action potential [GO:0001508]; calcium ion transmembrane import into cytosol [GO:0097553]; cellular response to amino acid stimulus [GO:0071230]; cellular response to dsRNA [GO:0071359]; cellular response to growth factor stimulus [GO:0071363]; cellular response to lipid [GO:0071396]; cellular response to magnesium ion [GO:0071286]; cellular response to manganese ion [GO:0071287]; cellular response to zinc ion [GO:0071294]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; dendritic spine organization [GO:0097061]; excitatory postsynaptic potential [GO:0060079]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of cell death [GO:0010942]; positive regulation of excitatory postsynaptic potential [GO:2000463]; protein tetramerization [GO:0051262]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; response to amine [GO:0014075]; response to ammonium ion [GO:0060359]; response to calcium ion [GO:0051592]; response to carbohydrate [GO:0009743]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to fungicide [GO:0060992]; response to light stimulus [GO:0009416]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to organic cyclic compound [GO:0014070]; response to other organism [GO:0051707]; rhythmic process [GO:0048511]; spinal cord development [GO:0021510]; synaptic transmission, glutamatergic [GO:0035249]		cell [GO:0005623]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; neuron projection [GO:0043005]; NMDA selective glutamate receptor complex [GO:0017146]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	ATPase binding [GO:0051117]; cell adhesion molecule binding [GO:0050839]; glutamate binding [GO:0016595]; glutamate-gated calcium ion channel activity [GO:0022849]; glutamate receptor activity [GO:0008066]; glutamate receptor binding [GO:0035254]; ionotropic glutamate receptor activity [GO:0004970]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; zinc ion binding [GO:0008270]
d2y88a__d2w79a___1			Actinobacteria	Thermotogae	cytoplasm [GO:0005737]; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]; phosphoribosylanthranilate isomerase activity [GO:0004640]; histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]	cytoplasm [GO:0005737]; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]; histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]	histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]	histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]; phosphoribosylanthranilate isomerase activity [GO:0004640]	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]
d2y8eb__d1nipa___1	Metazoa		Arthropoda	Proteobacteria	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; synapse [GO:0045202]; vesicle [GO:0031982]; actin binding [GO:0003779]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; axon guidance [GO:0007411]; compound eye morphogenesis [GO:0001745]; defense response to fungus [GO:0050832]; exocytosis [GO:0006887]; germarium-derived egg chamber formation [GO:0007293]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; oocyte microtubule cytoskeleton polarization [GO:0008103]; phototransduction [GO:0007602]; pole plasm oskar mRNA localization [GO:0045451]; R7 cell development [GO:0045467]; Rab protein signal transduction [GO:0032482]; regulation of postsynaptic membrane potential [GO:0060078]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	axon guidance [GO:0007411]; compound eye morphogenesis [GO:0001745]; defense response to fungus [GO:0050832]; exocytosis [GO:0006887]; germarium-derived egg chamber formation [GO:0007293]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; oocyte microtubule cytoskeleton polarization [GO:0008103]; phototransduction [GO:0007602]; pole plasm oskar mRNA localization [GO:0045451]; R7 cell development [GO:0045467]; Rab protein signal transduction [GO:0032482]; regulation of postsynaptic membrane potential [GO:0060078]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192]	nitrogen fixation [GO:0009399]	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; synapse [GO:0045202]; vesicle [GO:0031982]	molybdenum-iron nitrogenase complex [GO:0016612]	actin binding [GO:0003779]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d2y8ub__d3s6oc___1	Fungi		Ascomycota	Proteobacteria	chitin deacetylase activity [GO:0004099]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			chitin deacetylase activity [GO:0004099]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]
d2y96a__d1r6ha1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; protein homodimerization activity [GO:0042803]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; prenylated protein tyrosine phosphatase activity [GO:0004727]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cellular response to leukemia inhibitory factor [GO:1990830]; endothelial cell migration [GO:0043542]; Notch signaling pathway [GO:0007219]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of vascular permeability [GO:0043117]; regulation of transcription, DNA-templated [GO:0006355]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]	protein dephosphorylation [GO:0006470]	cellular response to leukemia inhibitory factor [GO:1990830]; endothelial cell migration [GO:0043542]; Notch signaling pathway [GO:0007219]; positive regulation of establishment of protein localization [GO:1904951]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of vascular permeability [GO:0043117]; regulation of transcription, DNA-templated [GO:0006355]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	protein homodimerization activity [GO:0042803]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	prenylated protein tyrosine phosphatase activity [GO:0004727]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d2y96a__d4ri5b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; protein homodimerization activity [GO:0042803]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine phosphatase activity [GO:0004725]; sodium channel regulator activity [GO:0017080]; liver regeneration [GO:0097421]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of mitotic cell cycle [GO:0045930]; protein dephosphorylation [GO:0006470]; regulation of membrane depolarization during action potential [GO:0098902]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	protein dephosphorylation [GO:0006470]	liver regeneration [GO:0097421]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of mitotic cell cycle [GO:0045930]; protein dephosphorylation [GO:0006470]; regulation of membrane depolarization during action potential [GO:0098902]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886]	protein homodimerization activity [GO:0042803]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine phosphatase activity [GO:0004725]; sodium channel regulator activity [GO:0017080]
d2y9na__d2zgma1__1	Fungi	Fungi	Ascomycota	Basidiomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	cellulose catabolic process [GO:0030245]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	extracellular region [GO:0005576]		cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d2ya9a__d3wika___1	Metazoa	Metazoa	Chordata	Chordata	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]; anoikis [GO:0043276]; intracellular signal transduction [GO:0035556]; neutrophil migration [GO:1990266]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein phosphorylation [GO:0006468]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]; ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	anoikis [GO:0043276]; intracellular signal transduction [GO:0035556]; neutrophil migration [GO:1990266]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein phosphorylation [GO:0006468]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]
d2yasa__d3r3zd___1	Viridiplantae		Streptophyta	Proteobacteria	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	haloacetate dehalogenase activity [GO:0018785]					aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	haloacetate dehalogenase activity [GO:0018785]
d2yb6a__d2eska2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; replication fork [GO:0005657]; XY body [GO:0001741]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular response to DNA damage stimulus [GO:0006974]; chiasma assembly [GO:0051026]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; histone H2A ubiquitination [GO:0033522]; histone lysine demethylation [GO:0070076]; in utero embryonic development [GO:0001701]; maintenance of chromatin silencing [GO:0006344]; meiotic telomere clustering [GO:0045141]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of histone phosphorylation [GO:0033128]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of reciprocal meiotic recombination [GO:0010845]; postreplication repair [GO:0006301]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; response to drug [GO:0042493]; response to UV [GO:0009411]; sperm axoneme assembly [GO:0007288]; spermatogenesis [GO:0007283]; synaptonemal complex organization [GO:0070193]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cellular response to DNA damage stimulus [GO:0006974]; chiasma assembly [GO:0051026]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; histone H2A ubiquitination [GO:0033522]; histone lysine demethylation [GO:0070076]; in utero embryonic development [GO:0001701]; maintenance of chromatin silencing [GO:0006344]; meiotic telomere clustering [GO:0045141]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of histone phosphorylation [GO:0033128]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of reciprocal meiotic recombination [GO:0010845]; postreplication repair [GO:0006301]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; response to drug [GO:0042493]; response to UV [GO:0009411]; spermatogenesis [GO:0007283]; sperm axoneme assembly [GO:0007288]; synaptonemal complex organization [GO:0070193]; ubiquitin-dependent protein catabolic process [GO:0006511]	cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell [GO:0005623]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; HULC complex [GO:0033503]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; replication fork [GO:0005657]; XY body [GO:0001741]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]
d2yb9a__d3keka___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; brush border [GO:0005903]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; cardiolipin binding [GO:1901612]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; oligopeptidase activity [GO:0070012]; peptide binding [GO:0042277]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; aging [GO:0007568]; amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; learning or memory [GO:0007611]; lung development [GO:0030324]; neuropeptide processing [GO:0061837]; neutrophil degranulation [GO:0043312]; peptide metabolic process [GO:0006518]; placenta development [GO:0001890]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neurogenesis [GO:0050769]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	aging [GO:0007568]; amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; learning or memory [GO:0007611]; lung development [GO:0030324]; neuropeptide processing [GO:0061837]; neutrophil degranulation [GO:0043312]; peptide metabolic process [GO:0006518]; placenta development [GO:0001890]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neurogenesis [GO:0050769]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	axon [GO:0030424]; brush border [GO:0005903]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cardiolipin binding [GO:1901612]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; oligopeptidase activity [GO:0070012]; peptide binding [GO:0042277]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d2ybea__d5bt8e___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; membrane raft [GO:0045121]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; protein-disulfide reductase activity [GO:0047134]; canonical glycolysis [GO:0061621]; cellular response to hypoxia [GO:0071456]; epithelial cell differentiation [GO:0030855]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of angiogenesis [GO:0016525]; phosphorylation [GO:0016310]; plasminogen activation [GO:0031639]; positive regulation of oxidative phosphorylation [GO:1903862]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; cellular response to hypoxia [GO:0071456]; epithelial cell differentiation [GO:0030855]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of angiogenesis [GO:0016525]; phosphorylation [GO:0016310]; plasminogen activation [GO:0031639]; positive regulation of oxidative phosphorylation [GO:1903862]	glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; membrane raft [GO:0045121]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; protein-disulfide reductase activity [GO:0047134]	ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]
d2ybkb__d4c8re2__1	Metazoa	Metazoa	Chordata	Chordata	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]; carnitine biosynthetic process [GO:0045329]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	carnitine biosynthetic process [GO:0045329]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]
d2ybrb1_d3mlvm1__1	Metazoa		Arthropoda		extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	defense response [GO:0006952]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]	structural molecule activity [GO:0005198]
d2ybrb1_d5meoa2__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	defense response [GO:0006952]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ybrg__d1zgla1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	defense response [GO:0006952]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ybrg__d5o04d1__1	Metazoa		Arthropoda		extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]		defense response [GO:0006952]		extracellular region [GO:0005576]		sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]	
d2ybvf__d1rblj___1			Cyanobacteria	Cyanobacteria		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]		reductive pentose-phosphate cycle [GO:0019253]				monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2ybvh__d1ausu___1		Viridiplantae	Cyanobacteria	Streptophyta		chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2ybvl__d1uzht___1		Viridiplantae	Cyanobacteria	Chlorophyta		chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]		magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d2yc1e__d1pkqf2__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	defense response [GO:0006952]	aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]	sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]
d2yc8a__d4bi6a___1						cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]
d2yc8i__d5tima___1						cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]; glycosome [GO:0020015]		triose-phosphate isomerase activity [GO:0004807]
d2yc8r__d1woaa___1				Apicomplexa		identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]				identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]
d2ycea1_d4ur8c___1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	5-dehydro-4-deoxyglucarate dehydratase activity [GO:0047448]; D-glucarate catabolic process [GO:0042838]	glycolytic process [GO:0006096]	D-glucarate catabolic process [GO:0042838]	cytoplasm [GO:0005737]		fructose-bisphosphate aldolase activity [GO:0004332]	5-dehydro-4-deoxyglucarate dehydratase activity [GO:0047448]
d2yced__d1f6pd___1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	fructose-bisphosphate aldolase activity [GO:0004332]	N-acetylneuraminate lyase activity [GO:0008747]
d2ycee__d3e96a___1			Crenarchaeota	Firmicutes	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		fructose-bisphosphate aldolase activity [GO:0004332]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d2yceg__d1j2wc___1			Crenarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	glycolytic process [GO:0006096]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	deoxyribose-phosphate aldolase activity [GO:0004139]
d2ycei__d2wnqd1__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	fructose-bisphosphate aldolase activity [GO:0004332]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d2ycga__d1ccpa___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2ycga__d5sx0a2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2ycix1_d4djfa___1			Firmicutes	Firmicutes	methyltransferase activity [GO:0008168]; pteridine-containing compound metabolic process [GO:0042558]	calcium ion binding [GO:0005509]; cobalamin binding [GO:0031419]; methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase activity [GO:0102036]; methyltransferase activity [GO:0008168]; carbon fixation [GO:0015977]; pteridine-containing compound metabolic process [GO:0042558]	pteridine-containing compound metabolic process [GO:0042558]	carbon fixation [GO:0015977]; pteridine-containing compound metabolic process [GO:0042558]			methyltransferase activity [GO:0008168]	calcium ion binding [GO:0005509]; cobalamin binding [GO:0031419]; methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase activity [GO:0102036]; methyltransferase activity [GO:0008168]
d2ycnb__d1c4ka2__1			Proteobacteria	Firmicutes	tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	cytoplasm [GO:0005737]; ornithine decarboxylase activity [GO:0004586]; cellular amino acid metabolic process [GO:0006520]	tyrosine metabolic process [GO:0006570]	cellular amino acid metabolic process [GO:0006520]		cytoplasm [GO:0005737]	tyrosine phenol-lyase activity [GO:0050371]	ornithine decarboxylase activity [GO:0004586]
d2ycpb__d2oata___1		Metazoa	Proteobacteria	Chordata	tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]	tyrosine metabolic process [GO:0006570]	arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; cellular amino acid biosynthetic process [GO:0008652]; L-proline biosynthetic process [GO:0055129]; protein hexamerization [GO:0034214]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	tyrosine phenol-lyase activity [GO:0050371]	ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]
d2ycpc__d5xmra___1			Proteobacteria	Apicomplexa	tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	tyrosine metabolic process [GO:0006570]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]			tyrosine phenol-lyase activity [GO:0050371]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d2ycpd__d1c7gc___1			Proteobacteria	Proteobacteria	tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	cytoplasm [GO:0005737]; tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	tyrosine metabolic process [GO:0006570]	tyrosine metabolic process [GO:0006570]		cytoplasm [GO:0005737]	tyrosine phenol-lyase activity [GO:0050371]	tyrosine phenol-lyase activity [GO:0050371]
d2ycta__d1g7xa___1			Proteobacteria	Proteobacteria	tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	tyrosine metabolic process [GO:0006570]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	tyrosine phenol-lyase activity [GO:0050371]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d2yd2a2_d1n64h2__1	Metazoa		Chordata		axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2yd3a2_d5lx9h1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]	integral component of membrane [GO:0016021]; intrinsic component of plasma membrane [GO:0031226]; plasma membrane [GO:0005886]; adipokinetic hormone receptor activity [GO:0097003]; adiponectin binding [GO:0055100]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; signaling receptor activity [GO:0038023]; adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; female pregnancy [GO:0007565]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; negative regulation of cell growth [GO:0030308]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of glucose import [GO:0046326]; regulation of fatty acid biosynthetic process [GO:0042304]; response to nutrient [GO:0007584]; vascular wound healing [GO:0061042]	cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]	adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; female pregnancy [GO:0007565]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; negative regulation of cell growth [GO:0030308]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of glucose import [GO:0046326]; regulation of fatty acid biosynthetic process [GO:0042304]; response to nutrient [GO:0007584]; vascular wound healing [GO:0061042]	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	integral component of membrane [GO:0016021]; intrinsic component of plasma membrane [GO:0031226]; plasma membrane [GO:0005886]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]	adipokinetic hormone receptor activity [GO:0097003]; adiponectin binding [GO:0055100]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; signaling receptor activity [GO:0038023]
d2yd4a1_d4pjeg1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein homodimerization activity [GO:0042803]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	axon [GO:0030424]; cell junction [GO:0030054]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein homodimerization activity [GO:0042803]; protein tyrosine phosphatase activity [GO:0004725]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2yd4a2_d1mcsb2__1	Metazoa		Chordata		axon [GO:0030424]; cell junction [GO:0030054]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein homodimerization activity [GO:0042803]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560]		negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; synaptic membrane adhesion [GO:0099560]		axon [GO:0030424]; cell junction [GO:0030054]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]		heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; protein homodimerization activity [GO:0042803]; protein tyrosine phosphatase activity [GO:0004725]	
d2yd5a1_d1fvdd2__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; chondroitin sulfate proteoglycan binding [GO:0035373]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; protein-containing complex binding [GO:0044877]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]		cell adhesion [GO:0007155]; cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]		extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]		cell adhesion molecule binding [GO:0050839]; chondroitin sulfate proteoglycan binding [GO:0035373]; heparin binding [GO:0008201]; protein-containing complex binding [GO:0044877]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	
d2yd7a1_d4pb0l2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; protein tyrosine phosphatase activity [GO:0004725]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]		heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]		extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		cell adhesion molecule binding [GO:0050839]; protein tyrosine phosphatase activity [GO:0004725]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	
d2yd8a2_d2gfbi1__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; chondroitin sulfate proteoglycan binding [GO:0035373]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; protein-containing complex binding [GO:0044877]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]		cell adhesion [GO:0007155]; cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]		extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]		cell adhesion molecule binding [GO:0050839]; chondroitin sulfate proteoglycan binding [GO:0035373]; heparin binding [GO:0008201]; protein-containing complex binding [GO:0044877]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	
d2ydaa__d2qjic___1			Crenarchaeota	Euryarchaeota	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; aromatic amino acid family biosynthetic process [GO:0009073]	carbohydrate metabolic process [GO:0005975]	aromatic amino acid family biosynthetic process [GO:0009073]			2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]
d2ydfa3_d4la0a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2ydfa3_d5ijea2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2ydfb2_d1ao6a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2ydfb2_d3v08a2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d2ydfb3_d5orfc3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d2ydnc2_d5a1ta2__1						L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]				L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]; nucleotide binding [GO:0000166]
d2ydwa__d1e6ia___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; nucleus [GO:0005634]; SAGA complex [GO:0000124]; SLIK (SAGA-like) complex [GO:0046695]; H3 histone acetyltransferase activity [GO:0010484]; histone acetyltransferase activity [GO:0004402]; lysine-acetylated histone binding [GO:0070577]; transcription coactivator activity [GO:0003713]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; nucleus [GO:0005634]; SAGA complex [GO:0000124]; SLIK (SAGA-like) complex [GO:0046695]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	H3 histone acetyltransferase activity [GO:0010484]; histone acetyltransferase activity [GO:0004402]; lysine-acetylated histone binding [GO:0070577]; transcription coactivator activity [GO:0003713]
d2ydwb__d5ueua1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]
d2ydxe1_d3lz6a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; methionine adenosyltransferase complex [GO:0048269]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; methionine adenosyltransferase regulator activity [GO:0048270]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; lung development [GO:0030324]; steroid metabolic process [GO:0008202]	methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	lung development [GO:0030324]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; methionine adenosyltransferase complex [GO:0048269]; nucleus [GO:0005634]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	enzyme binding [GO:0019899]; methionine adenosyltransferase regulator activity [GO:0048270]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]
d2ye7a__d3c11a___1	Metazoa	Fungi	Chordata	Ascomycota	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]
d2yeea__d4xira___1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d2yegb__d2ygaa___1	Metazoa	Fungi	Chordata	Ascomycota	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]
d2yeia__d4jasa2__1	Metazoa		Chordata	Thermotogae	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; protein autophosphorylation [GO:0046777]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	protein autophosphorylation [GO:0046777]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	integral component of plasma membrane [GO:0005887]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d2yekc__d4ir6a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	nucleus [GO:0005634]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d2yema__d5n16c1__1	Metazoa	Fungi	Chordata	Ascomycota	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	nucleus [GO:0005634]; lysine-acetylated histone binding [GO:0070577]; DNA repair [GO:0006281]; sporulation resulting in formation of a cellular spore [GO:0030435]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	DNA repair [GO:0006281]; sporulation resulting in formation of a cellular spore [GO:0030435]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleus [GO:0005634]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]	lysine-acetylated histone binding [GO:0070577]
d2yemb__d4qnsa1__1	Metazoa		Chordata	Apicomplexa	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	nucleus [GO:0005634]; H3 histone acetyltransferase activity [GO:0010484]; histone H3 acetylation [GO:0043966]; regulation of transcription, DNA-templated [GO:0006355]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	histone H3 acetylation [GO:0043966]; regulation of transcription, DNA-templated [GO:0006355]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleus [GO:0005634]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]	H3 histone acetyltransferase activity [GO:0010484]
d2yf1a2_d3qdja2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2yf1b__d3c5sa2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2yf1b__d5f7he1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]		
d2yfgb1_d3r3jc1__1				Apicomplexa		apicoplast [GO:0020011]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]; cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]		cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]		apicoplast [GO:0020011]; cytosol [GO:0005829]		glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]
d2yfhb1_d1euza2__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	glutamate biosynthetic process [GO:0006537]	cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d2yfic2_d1fskj___1		Metazoa	Proteobacteria	Chordata	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	aromatic compound catabolic process [GO:0019439]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	biphenyl 2,3-dioxygenase activity [GO:0018687]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2yfid__d3zfzb1__1			Proteobacteria	Firmicutes	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	aromatic compound catabolic process [GO:0019439]	response to antibiotic [GO:0046677]		integral component of membrane [GO:0016021]	biphenyl 2,3-dioxygenase activity [GO:0018687]	penicillin binding [GO:0008658]
d2yfid__d4hm7b___1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d2yfig2_d1fskd___1		Metazoa	Proteobacteria	Chordata	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	aromatic compound catabolic process [GO:0019439]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	biphenyl 2,3-dioxygenase activity [GO:0018687]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2yfih__d5cf2b___1			Proteobacteria	Actinobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	limonene-1,2-epoxide hydrolase activity [GO:0018744]	aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d2yfii2_d2ldka1__1			Proteobacteria	Actinobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]	
d2yfij__d1ndob___1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d2yfik2_d1o7wa2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d2yfil__d1hkxn___1		Metazoa	Proteobacteria	Chordata	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]; ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron migration [GO:2001222]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]	aromatic compound catabolic process [GO:0019439]	angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neuron migration [GO:2001222]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]		axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]	biphenyl 2,3-dioxygenase activity [GO:0018687]	ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]
d2yfjc2_d4hm1a2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	dioxygenase activity [GO:0051213]
d2yfjd__d4rzmb2__1			Proteobacteria	Actinobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	isomerase activity [GO:0016853]; antibiotic biosynthetic process [GO:0017000]	aromatic compound catabolic process [GO:0019439]	antibiotic biosynthetic process [GO:0017000]			biphenyl 2,3-dioxygenase activity [GO:0018687]	isomerase activity [GO:0016853]
d2yfje2_d2resa1__1			Proteobacteria	Actinobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	O-methyltransferase activity [GO:0008171]; antibiotic biosynthetic process [GO:0017000]	aromatic compound catabolic process [GO:0019439]	antibiotic biosynthetic process [GO:0017000]			biphenyl 2,3-dioxygenase activity [GO:0018687]	O-methyltransferase activity [GO:0008171]
d2yfjf__d1uljb___1			Proteobacteria	Actinobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d2yfjh__d3unld___1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	aromatic compound catabolic process [GO:0019439]	steroid metabolic process [GO:0008202]			biphenyl 2,3-dioxygenase activity [GO:0018687]	steroid delta-isomerase activity [GO:0004769]
d2yfjj__d1hkxl___1		Metazoa	Proteobacteria	Chordata	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]; ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron migration [GO:2001222]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]	aromatic compound catabolic process [GO:0019439]	angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neuron migration [GO:2001222]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]		axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]	biphenyl 2,3-dioxygenase activity [GO:0018687]	ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]
d2yfjl__d1jb4a___1		Metazoa	Proteobacteria	Chordata	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	aromatic compound catabolic process [GO:0019439]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]		cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	biphenyl 2,3-dioxygenase activity [GO:0018687]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]
d2yfla2_d1ww9a2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2yflb__d1ar0b___1		Metazoa	Proteobacteria	Chordata	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	aromatic compound catabolic process [GO:0019439]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]		cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	biphenyl 2,3-dioxygenase activity [GO:0018687]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]
d2yflc2_d1z01a2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d2yfle2_d4a81a___1		Viridiplantae	Proteobacteria	Streptophyta	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]	biphenyl 2,3-dioxygenase activity [GO:0018687]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d2yflg2_d3gcfh2__1			Proteobacteria	Actinobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d2yfll__d4cjna1__1			Proteobacteria	Firmicutes	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; response to antibiotic [GO:0046677]	aromatic compound catabolic process [GO:0019439]	response to antibiotic [GO:0046677]			biphenyl 2,3-dioxygenase activity [GO:0018687]	penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]
d2yfqb1_d1nqti2__1		Metazoa	Firmicutes	Chordata	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]; glutamate catabolic process via 2-hydroxyglutarate [GO:0019552]; oxidation-reduction process [GO:0055114]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase (NAD+) activity [GO:0004352]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d2yfwd__d1p34h___1	Fungi	Metazoa	Ascomycota	Chordata	2-micrometer circle DNA [GO:0005729]; CENP-A containing nucleosome [GO:0043505]; condensed chromosome kinetochore [GO:0000777]; condensed nuclear chromosome, centromeric region [GO:0000780]; centromeric DNA binding [GO:0019237]; protein heterodimerization activity [GO:0046982]; 2-micrometer plasmid partitioning [GO:0030543]; kinetochore assembly [GO:0051382]; mitotic sister chromatid segregation [GO:0000070]; protein localization to CENP-A containing chromatin [GO:0061644]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	2-micrometer plasmid partitioning [GO:0030543]; kinetochore assembly [GO:0051382]; mitotic sister chromatid segregation [GO:0000070]; protein localization to CENP-A containing chromatin [GO:0061644]		2-micrometer circle DNA [GO:0005729]; CENP-A containing nucleosome [GO:0043505]; condensed chromosome kinetochore [GO:0000777]; condensed nuclear chromosome, centromeric region [GO:0000780]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	centromeric DNA binding [GO:0019237]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2yfwf__d1p3ih___1	Fungi	Metazoa	Ascomycota	Chordata	2-micrometer circle DNA [GO:0005729]; CENP-A containing nucleosome [GO:0043505]; condensed chromosome kinetochore [GO:0000777]; condensed nuclear chromosome, centromeric region [GO:0000780]; centromeric DNA binding [GO:0019237]; protein heterodimerization activity [GO:0046982]; 2-micrometer plasmid partitioning [GO:0030543]; kinetochore assembly [GO:0051382]; mitotic sister chromatid segregation [GO:0000070]; protein localization to CENP-A containing chromatin [GO:0061644]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	2-micrometer plasmid partitioning [GO:0030543]; kinetochore assembly [GO:0051382]; mitotic sister chromatid segregation [GO:0000070]; protein localization to CENP-A containing chromatin [GO:0061644]		2-micrometer circle DNA [GO:0005729]; CENP-A containing nucleosome [GO:0043505]; condensed chromosome kinetochore [GO:0000777]; condensed nuclear chromosome, centromeric region [GO:0000780]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	centromeric DNA binding [GO:0019237]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d2yg1a__d3nv3a___1	Fungi	Metazoa	Basidiomycota	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	cellulose catabolic process [GO:0030245]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]
d2ygfa__d4wuda1__1	Fungi		Ascomycota	Proteobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; DNA-dependent ATPase activity [GO:0008094]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d2ygxa__d5veuc___1		Metazoa	Actinobacteria	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; aromatase activity [GO:0070330]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxygen binding [GO:0019825]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]; testosterone 6-beta-hydroxylase activity [GO:0050649]; alkaloid catabolic process [GO:0009822]; drug catabolic process [GO:0042737]; estrogen metabolic process [GO:0008210]; lipid hydroxylation [GO:0002933]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	alkaloid catabolic process [GO:0009822]; drug catabolic process [GO:0042737]; estrogen metabolic process [GO:0008210]; lipid hydroxylation [GO:0002933]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxygen binding [GO:0019825]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]; testosterone 6-beta-hydroxylase activity [GO:0050649]
d2ygyb__d4woqh___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	N-acetylneuraminate lyase activity [GO:0008747]
d2ygyb__d5c2xb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	deoxyribose-phosphate aldolase activity [GO:0004139]
d2yhea1_d5fqca___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	metal ion binding [GO:0046872]
d2yhea2_d1pz4a1__1		Metazoa	Proteobacteria	Arthropoda	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]						metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	
d2yheb1_d4rl0b___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2yheb2_d2cg2a1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	outer membrane-bounded periplasmic space [GO:0030288]; alkyl sulfatase activity [GO:0018741]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]; dodecyl sulfate metabolic process [GO:0018909]		dodecyl sulfate metabolic process [GO:0018909]		outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	alkyl sulfatase activity [GO:0018741]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]
d2yhec1_d5k4na___1			Proteobacteria		metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]						metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	
d2yhee1_d2bmib___1			Proteobacteria	Bacteroidetes	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2yhfc__d5bzpa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]; cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]	epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d2yhff__d1uexa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]; cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d2yhka__d3fqaa___1			Proteobacteria	Cyanobacteria	tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	tyrosine metabolic process [GO:0006570]	chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]		cytoplasm [GO:0005737]	tyrosine phenol-lyase activity [GO:0050371]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d2yhob1_d1ayzb___1	Metazoa	Fungi	Chordata	Ascomycota	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cytoskeletal protein binding [GO:0008092]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cholesterol homeostasis [GO:0042632]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]; ubiquitin-dependent protein catabolic process [GO:0006511]	chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; HULC complex [GO:0033503]; MUB1-RAD6-UBR2 ubiquitin ligase complex [GO:1990304]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; Rad6-Rad18 complex [GO:0097505]; UBR1-RAD6 ubiquitin ligase complex [GO:1990303]; ATP binding [GO:0005524]; proteasome binding [GO:0070628]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]; chromatin silencing at telomere [GO:0006348]; cytoplasm protein quality control by the ubiquitin-proteasome system [GO:0071629]; DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA-templated transcription, termination [GO:0006353]; double-strand break repair via homologous recombination [GO:0000724]; error-free postreplication DNA repair [GO:0042275]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; histone monoubiquitination [GO:0010390]; meiotic DNA double-strand break formation [GO:0042138]; mitotic G1 DNA damage checkpoint [GO:0031571]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; regulation of dipeptide transport [GO:0090089]; sporulation resulting in formation of a cellular spore [GO:0030435]; stress-induced homeostatically regulated protein degradation pathway [GO:0120174]; telomere maintenance via recombination [GO:0000722]; transcription by RNA polymerase II [GO:0006366]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	cholesterol homeostasis [GO:0042632]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]; ubiquitin-dependent protein catabolic process [GO:0006511]	chromatin silencing at telomere [GO:0006348]; cytoplasm protein quality control by the ubiquitin-proteasome system [GO:0071629]; DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA-templated transcription, termination [GO:0006353]; double-strand break repair via homologous recombination [GO:0000724]; error-free postreplication DNA repair [GO:0042275]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; histone monoubiquitination [GO:0010390]; meiotic DNA double-strand break formation [GO:0042138]; mitotic G1 DNA damage checkpoint [GO:0031571]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; regulation of dipeptide transport [GO:0090089]; sporulation resulting in formation of a cellular spore [GO:0030435]; stress-induced homeostatically regulated protein degradation pathway [GO:0120174]; telomere maintenance via recombination [GO:0000722]; transcription by RNA polymerase II [GO:0006366]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; HULC complex [GO:0033503]; MUB1-RAD6-UBR2 ubiquitin ligase complex [GO:1990304]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; Rad6-Rad18 complex [GO:0097505]; UBR1-RAD6 ubiquitin ligase complex [GO:1990303]	cytoskeletal protein binding [GO:0008092]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; proteasome binding [GO:0070628]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]
d2yhsa1_d1jpnb1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; signal recognition particle binding [GO:0005047]; protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]	signal recognition particle [GO:0048500]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; signal recognition particle binding [GO:0005047]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d2yiza__d2v19l___1			Actinobacteria	Deinococcus-Thermus	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]			extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2yizb__d2devf___1			Actinobacteria	Deinococcus-Thermus	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	
d2yizb__d2vxai___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]			extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2yizd__d2vxak___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]			extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2yj0b__d2v19d___1			Actinobacteria	Deinococcus-Thermus	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]			extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2yj0c__d2dehc___1			Actinobacteria	Deinococcus-Thermus	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	
d2yj0d__d2ux9f___1			Actinobacteria	Deinococcus-Thermus	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]			extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d2yjec2_d3ay9a1__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]
d2yjha1_d2r6ka2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	thioredoxin peroxidase activity [GO:0008379]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d2yjja__d2fzfa1__1			Actinobacteria	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2yjjb__d5da5g1__1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]
d2yjjc__d4dyua___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2yjjf__d4to9b___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2yjjg__d3uofa___1			Actinobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2yjka__d2cf7f___1			Actinobacteria	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d2yjkc__d1l8if___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2yjke__d4cmyx___1			Actinobacteria	Chlorobi	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]
d2yjki__d3hx2h___1			Actinobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		ferric iron binding [GO:0008199]	
d2yjkj__d2jd60___1			Actinobacteria	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]
d2yjkj__d5d8yk___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2yjkk__d2jd8u___1			Actinobacteria	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]
d2yjpa__d1vfea___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]		antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d2yjpc__d1ez9a___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d2yjwa1_d3cwva1__1	Metazoa		Chordata	Proteobacteria	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; DNA topological change [GO:0006265]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA topological change [GO:0006265]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]
d2yjxa1_d5ctwb___1	Metazoa		Chordata	Firmicutes	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d2yjyb__d3fula3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2yjyb__d3q0pa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]
d2yl3a__d3m79h___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2ylbc__d1vu3q___1			Proteobacteria		cytosol [GO:0005829]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]		pathogenesis [GO:0009405]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]		cytosol [GO:0005829]		identical protein binding [GO:0042802]; RNA binding [GO:0003723]	
d2ylbd__d4mmkg___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d2ylda__d3m4ba___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2ylda__d5js5a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2ylkc__d4b96a1__1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	integral component of membrane [GO:0016021]; cellulose binding [GO:0030248]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		integral component of membrane [GO:0016021]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]	cellulose binding [GO:0030248]
d2ylqa__d4ozte___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; androgen binding [GO:0005497]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; nuclear receptor activity [GO:0004879]; POU domain binding [GO:0070974]; protein dimerization activity [GO:0046983]; RNA polymerase II general transcription initiation factor binding [GO:0001091]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]; activation of prostate induction by androgen receptor signaling pathway [GO:0060520]; androgen receptor signaling pathway [GO:0030521]; animal organ formation [GO:0048645]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to steroid hormone stimulus [GO:0071383]; cellular response to testosterone stimulus [GO:0071394]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; epithelial cell morphogenesis [GO:0003382]; in utero embryonic development [GO:0001701]; intracellular receptor signaling pathway [GO:0030522]; lateral sprouting involved in mammary gland duct morphogenesis [GO:0060599]; Leydig cell differentiation [GO:0033327]; male genitalia morphogenesis [GO:0048808]; male somatic sex determination [GO:0019102]; mammary gland alveolus development [GO:0060749]; morphogenesis of an epithelial fold [GO:0060571]; multicellular organism growth [GO:0035264]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of integrin biosynthetic process [GO:0045720]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of integrin biosynthetic process [GO:0045726]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription, DNA-templated [GO:0045893]; prostate gland development [GO:0030850]; prostate gland epithelium morphogenesis [GO:0060740]; prostate gland growth [GO:0060736]; protein deubiquitination [GO:0016579]; regulation of developmental growth [GO:0048638]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of systemic arterial blood pressure [GO:0003073]; seminiferous tubule development [GO:0072520]; sex differentiation [GO:0007548]; signal transduction [GO:0007165]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]	nucleus [GO:0005634]; ecdysone binding [GO:0035100]; nuclear receptor activity [GO:0004879]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]; ecdysone receptor-mediated signaling pathway [GO:0035076]	activation of prostate induction by androgen receptor signaling pathway [GO:0060520]; androgen receptor signaling pathway [GO:0030521]; animal organ formation [GO:0048645]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to steroid hormone stimulus [GO:0071383]; cellular response to testosterone stimulus [GO:0071394]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; epithelial cell morphogenesis [GO:0003382]; intracellular receptor signaling pathway [GO:0030522]; in utero embryonic development [GO:0001701]; lateral sprouting involved in mammary gland duct morphogenesis [GO:0060599]; Leydig cell differentiation [GO:0033327]; male genitalia morphogenesis [GO:0048808]; male somatic sex determination [GO:0019102]; mammary gland alveolus development [GO:0060749]; morphogenesis of an epithelial fold [GO:0060571]; multicellular organism growth [GO:0035264]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of integrin biosynthetic process [GO:0045720]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of integrin biosynthetic process [GO:0045726]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; prostate gland development [GO:0030850]; prostate gland epithelium morphogenesis [GO:0060740]; prostate gland growth [GO:0060736]; protein deubiquitination [GO:0016579]; regulation of developmental growth [GO:0048638]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of systemic arterial blood pressure [GO:0003073]; seminiferous tubule development [GO:0072520]; sex differentiation [GO:0007548]; signal transduction [GO:0007165]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription, DNA-templated [GO:0006351]; transcription initiation from RNA polymerase II promoter [GO:0006367]	ecdysone receptor-mediated signaling pathway [GO:0035076]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	nucleus [GO:0005634]	androgen binding [GO:0005497]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; nuclear receptor activity [GO:0004879]; POU domain binding [GO:0070974]; protein dimerization activity [GO:0046983]; RNA polymerase II general transcription initiation factor binding [GO:0001091]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]	ecdysone binding [GO:0035100]; nuclear receptor activity [GO:0004879]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]
d2ylra2_d1trba2__1			Actinobacteria	Proteobacteria	phenylacetone monooxygenase activity [GO:0033776]	cytosol [GO:0005829]; flavin adenine dinucleotide binding [GO:0050660]; thioredoxin-disulfide reductase activity [GO:0004791]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]		cytosol [GO:0005829]	phenylacetone monooxygenase activity [GO:0033776]	flavin adenine dinucleotide binding [GO:0050660]; thioredoxin-disulfide reductase activity [GO:0004791]
d2ylsa2_d1nhsa2__1			Actinobacteria	Firmicutes	phenylacetone monooxygenase activity [GO:0033776]	cell [GO:0005623]; flavin adenine dinucleotide binding [GO:0050660]; NADH peroxidase activity [GO:0016692]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]	phenylacetone monooxygenase activity [GO:0033776]	flavin adenine dinucleotide binding [GO:0050660]; NADH peroxidase activity [GO:0016692]
d2ym0b1_d4d3ed___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d2ymdd__d2wnle1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2ymde__d3sq9h___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d2ymdh__d3wtic1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2ymea__d2zjvb1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2ymeb__d5ouga___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d2ymee__d2zjua1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2ymef__d2xz6g___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2ymei__d1uv6c___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2ymua1_d4ggaa___1		Metazoa	Cyanobacteria	Chordata	integral component of membrane [GO:0016021]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; spindle pole [GO:0000922]; anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; protein C-terminus binding [GO:0008022]; ubiquitin-protein transferase activator activity [GO:0097027]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly [GO:0090307]; mitotic spindle assembly checkpoint [GO:0007094]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020]; regulation of mitotic cell cycle phase transition [GO:1901990]; ubiquitin-dependent protein catabolic process [GO:0006511]		anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly [GO:0090307]; mitotic spindle assembly checkpoint [GO:0007094]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020]; regulation of mitotic cell cycle phase transition [GO:1901990]; ubiquitin-dependent protein catabolic process [GO:0006511]	integral component of membrane [GO:0016021]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; spindle pole [GO:0000922]		anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; protein C-terminus binding [GO:0008022]; ubiquitin-protein transferase activator activity [GO:0097027]
d2ymub1_d3mxxa1__1		Metazoa	Cyanobacteria	Chordata	integral component of membrane [GO:0016021]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]		histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	integral component of membrane [GO:0016021]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]		histone binding [GO:0042393]; methylated histone binding [GO:0035064]
d2ymub2_d5he0b___1		Metazoa	Cyanobacteria	Chordata	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]; alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]; cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein phosphorylation [GO:0006468]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]		cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein phosphorylation [GO:0006468]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]		alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]
d2ymxl1_d1svzb1__1		Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		antigen binding [GO:0003823]
d2ymxl1_d2jb6l1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ymxl2_d5w5lb1__1		Metazoa		Chordata		extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]		extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		
d2ymzc1_d1q8oa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2ymzc1_d3ogga1__1	Metazoa		Chordata		carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	extracellular region [GO:0005576]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d2ymzd1_d2dtyc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]
d2ymzf1_d3b9ca___1	Metazoa	Metazoa	Chordata	Chordata	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	cytoplasm [GO:0005737]; intracellular [GO:0005622]; carbohydrate binding [GO:0030246]				cytoplasm [GO:0005737]; intracellular [GO:0005622]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]
d2ynab__d2z9ga___1					host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2ynba__d1w0zu___1		Metazoa		Chordata	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]
d2yndb1_d4kova___1			Apicomplexa	Proteobacteria	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]	N-terminal protein myristoylation [GO:0006499]				glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]
d2ynea1_d1iyla1__1		Fungi	Apicomplexa	Ascomycota	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]	cytoplasm [GO:0005737]; drug binding [GO:0008144]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; pathogenesis [GO:0009405]	N-terminal protein myristoylation [GO:0006499]	N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; pathogenesis [GO:0009405]		cytoplasm [GO:0005737]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]	drug binding [GO:0008144]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d2ynmb__d3rboa___1			Cyanobacteria		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on iron-sulfur proteins as donors [GO:0016730]; oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor [GO:0016636]; light-independent chlorophyll biosynthetic process [GO:0036068]; photosynthesis, dark reaction [GO:0019685]		light-independent chlorophyll biosynthetic process [GO:0036068]; photosynthesis, dark reaction [GO:0019685]				4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on iron-sulfur proteins as donors [GO:0016730]; oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor [GO:0016636]	
d2ynta1_d3wxca___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]			metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2ynvb__d2ohje1__1			Proteobacteria	Euryarchaeota	metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d2yoaa1_d1djwb2__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]
d2yoab__d2ki6f___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of vesicle fusion [GO:0031340]; protein heterooligomerization [GO:0051291]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to calcium ion [GO:0051592]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular organelle [GO:0043229]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipid binding [GO:0005543]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d2yooa__d2ij3a___1			Actinobacteria	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; cholesterol catabolic process [GO:0006707]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cholesterol catabolic process [GO:0006707]			cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d2yooc__d3nv6a___1			Actinobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; cholesterol catabolic process [GO:0006707]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cholesterol catabolic process [GO:0006707]				heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2yood__d5dqna___1			Actinobacteria	Actinobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; cholesterol catabolic process [GO:0006707]	cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; cholesterol catabolic process [GO:0006707]	cholesterol catabolic process [GO:0006707]	cholesterol catabolic process [GO:0006707]			heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2yoxa__d3cnkb___1		Metazoa		Chordata		actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]		actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]		actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d2yoxb__d1ogpa1__1		Viridiplantae		Streptophyta		cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]		chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]		heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]
d2yoxb__d4lq1d1__1				Proteobacteria		cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]		carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]		cytosol [GO:0005829]		1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2yoyb__d1cxea1__1				Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2yp3a1_d4wsxi___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2yp4a1_d5br3a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2yp7a1_d5bqyc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2yp8a1_d4edba___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2yp8a1_d5t0ea___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2ypga__d4qy1m___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2ypgc__d4lkja___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d2ypra__d1puef___1	Metazoa	Metazoa	Chordata	Chordata	nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]; cell differentiation [GO:0030154]; neuron fate specification [GO:0048665]; neuron maturation [GO:0042551]; positive regulation of gene expression [GO:0010628]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; NFAT protein binding [GO:0051525]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; anatomical structure regression [GO:0060033]; apoptotic process involved in blood vessel morphogenesis [GO:1902262]; cell differentiation [GO:0030154]; cellular response to ethanol [GO:0071361]; erythrocyte differentiation [GO:0030218]; granulocyte differentiation [GO:0030851]; histone H3 acetylation [GO:0043966]; hypermethylation of CpG island [GO:0044027]; interleukin-6-mediated signaling pathway [GO:0070102]; lymphocyte differentiation [GO:0030098]; lymphoid progenitor cell differentiation [GO:0002320]; macrophage differentiation [GO:0030225]; myeloid dendritic cell differentiation [GO:0043011]; myeloid leukocyte differentiation [GO:0002573]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H4 acetylation [GO:0090241]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of erythrocyte differentiation [GO:0045646]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; somatic stem cell population maintenance [GO:0035019]; vasculature development [GO:0001944]	cell differentiation [GO:0030154]; neuron fate specification [GO:0048665]; neuron maturation [GO:0042551]; positive regulation of gene expression [GO:0010628]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]	anatomical structure regression [GO:0060033]; apoptotic process involved in blood vessel morphogenesis [GO:1902262]; cell differentiation [GO:0030154]; cellular response to ethanol [GO:0071361]; erythrocyte differentiation [GO:0030218]; granulocyte differentiation [GO:0030851]; histone H3 acetylation [GO:0043966]; hypermethylation of CpG island [GO:0044027]; interleukin-6-mediated signaling pathway [GO:0070102]; lymphocyte differentiation [GO:0030098]; lymphoid progenitor cell differentiation [GO:0002320]; macrophage differentiation [GO:0030225]; myeloid dendritic cell differentiation [GO:0043011]; myeloid leukocyte differentiation [GO:0002573]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H4 acetylation [GO:0090241]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of erythrocyte differentiation [GO:0045646]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; somatic stem cell population maintenance [GO:0035019]; vasculature development [GO:0001944]	nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleus [GO:0005634]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; NFAT protein binding [GO:0051525]; RNA binding [GO:0003723]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d2yprb__d1mdmb___1	Metazoa	Metazoa	Chordata	Chordata	nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]; cell differentiation [GO:0030154]; neuron fate specification [GO:0048665]; neuron maturation [GO:0042551]; positive regulation of gene expression [GO:0010628]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]	cytosol [GO:0005829]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; adult behavior [GO:0030534]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cerebral cortex development [GO:0021987]; embryonic cranial skeleton morphogenesis [GO:0048701]; humoral immune response [GO:0006959]; lateral ventricle development [GO:0021670]; multicellular organism development [GO:0007275]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of B cell receptor signaling pathway [GO:0050855]; skeletal muscle cell differentiation [GO:0035914]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366]	cell differentiation [GO:0030154]; neuron fate specification [GO:0048665]; neuron maturation [GO:0042551]; positive regulation of gene expression [GO:0010628]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]	adult behavior [GO:0030534]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cerebral cortex development [GO:0021987]; embryonic cranial skeleton morphogenesis [GO:0048701]; humoral immune response [GO:0006959]; lateral ventricle development [GO:0021670]; multicellular organism development [GO:0007275]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of B cell receptor signaling pathway [GO:0050855]; skeletal muscle cell differentiation [GO:0035914]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366]	nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleus [GO:0005634]	cytosol [GO:0005829]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d2ypvl1_d3a6bh___1		Metazoa	Proteobacteria	Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2ypvl1_d3wjla2__1		Metazoa	Proteobacteria	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2ypvl2_d2vxtl1__1		Metazoa	Proteobacteria	Chordata		cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]		activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]		cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d2ypvl2_d3bkyh2__1		Metazoa	Proteobacteria	Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2yqda1_d5pcfa1__1	Metazoa	Metazoa	Chordata	Chordata	kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RSC-type complex [GO:0016586]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; ATP-dependent chromatin remodeling [GO:0043044]; blastocyst formation [GO:0001825]; blood vessel remodeling [GO:0001974]; cardiac vascular smooth muscle cell development [GO:0060948]; epicardium-derived cardiac endothelial cell differentiation [GO:0003349]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; placenta development [GO:0001890]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription elongation from RNA polymerase II promoter [GO:0006368]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	ATP-dependent chromatin remodeling [GO:0043044]; blastocyst formation [GO:0001825]; blood vessel remodeling [GO:0001974]; cardiac vascular smooth muscle cell development [GO:0060948]; epicardium-derived cardiac endothelial cell differentiation [GO:0003349]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; placenta development [GO:0001890]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription elongation from RNA polymerase II promoter [GO:0006368]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RSC-type complex [GO:0016586]	nucleus [GO:0005634]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d2yqga1_d1edha1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; cornified envelope [GO:0001533]; desmosome [GO:0030057]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; intercalated disc [GO:0014704]; intracellular membrane-bounded organelle [GO:0043231]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication [GO:0086083]; bundle of His cell-Purkinje myocyte adhesion involved in cell communication [GO:0086073]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; desmosome organization [GO:0002934]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; maternal process involved in female pregnancy [GO:0060135]; Purkinje myocyte development [GO:0003165]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; response to progesterone [GO:0032570]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	bundle of His cell-Purkinje myocyte adhesion involved in cell communication [GO:0086073]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; desmosome organization [GO:0002934]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; maternal process involved in female pregnancy [GO:0060135]; Purkinje myocyte development [GO:0003165]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; response to progesterone [GO:0032570]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell surface [GO:0009986]; cornified envelope [GO:0001533]; desmosome [GO:0030057]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; intercalated disc [GO:0014704]; intracellular membrane-bounded organelle [GO:0043231]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication [GO:0086083]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d2yqwa__d3gzpa___1		Metazoa		Chordata		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]		chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d2yqwc__d2sodb___1		Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]		activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]		chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d2yqxb__d4rvpa___1		Viridiplantae		Streptophyta		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]						metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d2yr3a1_d4dvbl1__1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; actin binding [GO:0003779]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; myosin light chain kinase activity [GO:0004687]; protein kinase activity [GO:0004672]; aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cardiovascular system development [GO:0072358]; cellular hypotonic response [GO:0071476]; muscle contraction [GO:0006936]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]		aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cardiovascular system development [GO:0072358]; cellular hypotonic response [GO:0071476]; muscle contraction [GO:0006936]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]		actin cytoskeleton [GO:0015629]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]		actin binding [GO:0003779]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; myosin light chain kinase activity [GO:0004687]; protein kinase activity [GO:0004672]	
d2yrba1_d2b3rb1__1	Metazoa	Metazoa	Chordata	Chordata	axonemal microtubule [GO:0005879]; axoneme [GO:0005930]; bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary rootlet [GO:0035253]; ciliary transition zone [GO:0035869]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; photoreceptor connecting cilium [GO:0032391]; plasma membrane [GO:0005886]; thromboxane A2 receptor binding [GO:0031870]; camera-type eye development [GO:0043010]; cerebellum development [GO:0021549]; ciliary basal body-plasma membrane docking [GO:0097711]; cochlea development [GO:0090102]; corpus callosum development [GO:0022038]; determination of left/right symmetry [GO:0007368]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; establishment of planar polarity [GO:0001736]; establishment or maintenance of cell polarity [GO:0007163]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lateral ventricle development [GO:0021670]; liver development [GO:0001889]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neural tube patterning [GO:0021532]; non-motile cilium assembly [GO:1905515]; nose development [GO:0043584]; olfactory bulb development [GO:0021772]; pericardium development [GO:0060039]; regulation of smoothened signaling pathway [GO:0008589]	clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; 1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091]; autophagosome organization [GO:1905037]; cellular response to starvation [GO:0009267]; endocytosis [GO:0006897]; exocytosis [GO:0006887]; macroautophagy [GO:0016236]; negative regulation of zinc ion transmembrane transport [GO:0071583]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphorylation [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]	camera-type eye development [GO:0043010]; cerebellum development [GO:0021549]; ciliary basal body-plasma membrane docking [GO:0097711]; cochlea development [GO:0090102]; corpus callosum development [GO:0022038]; determination of left/right symmetry [GO:0007368]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; establishment of planar polarity [GO:0001736]; establishment or maintenance of cell polarity [GO:0007163]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lateral ventricle development [GO:0021670]; liver development [GO:0001889]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; neural tube patterning [GO:0021532]; non-motile cilium assembly [GO:1905515]; nose development [GO:0043584]; olfactory bulb development [GO:0021772]; pericardium development [GO:0060039]; regulation of smoothened signaling pathway [GO:0008589]	autophagosome organization [GO:1905037]; cellular response to starvation [GO:0009267]; endocytosis [GO:0006897]; exocytosis [GO:0006887]; macroautophagy [GO:0016236]; negative regulation of zinc ion transmembrane transport [GO:0071583]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]	axonemal microtubule [GO:0005879]; axoneme [GO:0005930]; bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary rootlet [GO:0035253]; ciliary transition zone [GO:0035869]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; photoreceptor connecting cilium [GO:0032391]; plasma membrane [GO:0005886]	clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	thromboxane A2 receptor binding [GO:0031870]	1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091]
d2yroa1_d2ymzb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]		carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2yrsd__d3ciub1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2yrsd__d5nb3k___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2yrsi__d2gl3b___1	Metazoa		Chordata	Actinobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d2yrsm__d5c6ya___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2yrwa3_d2gpwc1__1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2yrxa3_d2w71c3__1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2yrxa3_d3lp8a3__1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d2ys1a1_d1xd4b3__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell [GO:0005623]; centrosome [GO:0005813]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; dendritic spine head [GO:0044327]; endocytic vesicle membrane [GO:0030666]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; microtubule [GO:0005874]; midbody [GO:0030496]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic cup [GO:0001891]; phagocytic vesicle membrane [GO:0030670]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic endocytic zone membrane [GO:0098844]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; trans-Golgi network [GO:0005802]; D2 dopamine receptor binding [GO:0031749]; enzyme binding [GO:0019899]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; SH3 domain binding [GO:0017124]; WW domain binding [GO:0050699]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; cellular response to carbon monoxide [GO:0071245]; cellular response to dopamine [GO:1903351]; cellular response to nitric oxide [GO:0071732]; cellular response to X-ray [GO:0071481]; coronary vasculature development [GO:0060976]; endocytosis [GO:0006897]; G protein-coupled receptor internalization [GO:0002031]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi to plasma membrane transport [GO:0006893]; macropinocytosis [GO:0044351]; membrane organization [GO:0061024]; mitochondrial fission [GO:0000266]; negative regulation of membrane tubulation [GO:1903526]; negative regulation of non-motile cilium assembly [GO:1902856]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of apoptotic process [GO:0043065]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phagocytosis [GO:0050766]; positive regulation of sodium:potassium-exchanging ATPase activity [GO:1903408]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of axon extension [GO:0030516]; regulation of Golgi organization [GO:1903358]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of Rac protein signal transduction [GO:0035020]; regulation of synapse structure or activity [GO:0050803]; regulation of transcription, DNA-templated [GO:0006355]; response to cocaine [GO:0042220]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle transport [GO:0048489]; transferrin transport [GO:0033572]; ventricular septum development [GO:0003281]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleosome [GO:0000786]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; DNA binding [GO:0003677]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein heterodimerization activity [GO:0046982]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; SH3 domain binding [GO:0017124]; axon guidance [GO:0007411]; B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; vitellogenesis [GO:0007296]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; aorta development [GO:0035904]; cellular response to carbon monoxide [GO:0071245]; cellular response to dopamine [GO:1903351]; cellular response to nitric oxide [GO:0071732]; cellular response to X-ray [GO:0071481]; coronary vasculature development [GO:0060976]; endocytosis [GO:0006897]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi to plasma membrane transport [GO:0006893]; G protein-coupled receptor internalization [GO:0002031]; macropinocytosis [GO:0044351]; membrane organization [GO:0061024]; mitochondrial fission [GO:0000266]; negative regulation of membrane tubulation [GO:1903526]; negative regulation of non-motile cilium assembly [GO:1902856]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of apoptotic process [GO:0043065]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phagocytosis [GO:0050766]; positive regulation of sodium:potassium-exchanging ATPase activity [GO:1903408]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of axon extension [GO:0030516]; regulation of Golgi organization [GO:1903358]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of Rac protein signal transduction [GO:0035020]; regulation of synapse structure or activity [GO:0050803]; regulation of transcription, DNA-templated [GO:0006355]; response to cocaine [GO:0042220]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle transport [GO:0048489]; transferrin transport [GO:0033572]; ventricular septum development [GO:0003281]	axon guidance [GO:0007411]; B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; vitellogenesis [GO:0007296]	axon [GO:0030424]; cell [GO:0005623]; centrosome [GO:0005813]; clathrin-coated endocytic vesicle [GO:0045334]; clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; dendritic spine head [GO:0044327]; endocytic vesicle membrane [GO:0030666]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; microtubule [GO:0005874]; midbody [GO:0030496]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic cup [GO:0001891]; phagocytic vesicle membrane [GO:0030670]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic endocytic zone membrane [GO:0098844]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; trans-Golgi network [GO:0005802]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleosome [GO:0000786]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	D2 dopamine receptor binding [GO:0031749]; enzyme binding [GO:0019899]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; microtubule binding [GO:0008017]; nitric-oxide synthase binding [GO:0050998]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; SH3 domain binding [GO:0017124]; WW domain binding [GO:0050699]	DNA binding [GO:0003677]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein heterodimerization activity [GO:0046982]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; SH3 domain binding [GO:0017124]
d2ys6a3_d1ulza1__1			Firmicutes	Aquificae	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]				ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]
d2ys7a1_d2yznb1__1			Firmicutes	Deinococcus-Thermus	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2yssc__d1lsya___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2yswc__d3s0ca___1			Aquificae	Euryarchaeota	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]	3-dehydroquinate dehydratase activity [GO:0003855]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d2ysxa1_d3eaca___1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; SH3 domain binding [GO:0017124]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; immunoglobulin mediated immune response [GO:0016064]; inositol phosphate metabolic process [GO:0043647]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of bone resorption [GO:0045779]; negative regulation of immune response [GO:0050777]; negative regulation of interleukin-6 biosynthetic process [GO:0045409]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of neutrophil differentiation [GO:0045659]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of signal transduction [GO:0009968]; phosphate-containing compound metabolic process [GO:0006796]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of erythrocyte differentiation [GO:0045648]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; immunoglobulin mediated immune response [GO:0016064]; inositol phosphate metabolic process [GO:0043647]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of bone resorption [GO:0045779]; negative regulation of immune response [GO:0050777]; negative regulation of interleukin-6 biosynthetic process [GO:0045409]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of neutrophil differentiation [GO:0045659]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of signal transduction [GO:0009968]; phosphate-containing compound metabolic process [GO:0006796]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of erythrocyte differentiation [GO:0045648]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; SH3 domain binding [GO:0017124]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]
d2yt7a1_d2edva1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; chemical synaptic transmission [GO:0007268]; in utero embryonic development [GO:0001701]; negative regulation of catalytic activity [GO:0043086]; protein transport [GO:0015031]; regulation of gene expression [GO:0010468]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; establishment of protein localization to membrane [GO:0090150]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	chemical synaptic transmission [GO:0007268]; in utero embryonic development [GO:0001701]; negative regulation of catalytic activity [GO:0043086]; protein transport [GO:0015031]; regulation of gene expression [GO:0010468]	establishment of protein localization to membrane [GO:0090150]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]	cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	amyloid-beta binding [GO:0001540]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]	
d2ytca1_d2cpfa1__1	Metazoa	Metazoa	Chordata	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]; calcium-dependent protein binding [GO:0048306]; metal ion binding [GO:0046872]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; U6 snRNA binding [GO:0017070]; cellular response to drug [GO:0035690]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of RNA splicing [GO:0033120]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA binding [GO:0003723]; mRNA cis splicing, via spliceosome [GO:0045292]; multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	cellular response to drug [GO:0035690]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of RNA splicing [GO:0033120]	mRNA cis splicing, via spliceosome [GO:0045292]; multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Prp19 complex [GO:0000974]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	calcium-dependent protein binding [GO:0048306]; metal ion binding [GO:0046872]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; U6 snRNA binding [GO:0017070]	RNA binding [GO:0003723]
d2yvca1_d4rmaa2__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]
d2yvcb2_d2aeha2__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]; actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]
d2yvcc2_d2d9xa1__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; lipid binding [GO:0008289]; sterol binding [GO:0032934]; fat cell differentiation [GO:0045444]; lipid transport [GO:0006869]; positive regulation of sequestering of triglyceride [GO:0010890]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	fat cell differentiation [GO:0045444]; lipid transport [GO:0006869]; positive regulation of sequestering of triglyceride [GO:0010890]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	lipid binding [GO:0008289]; sterol binding [GO:0032934]
d2yvcc3_d2lz6a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d2yvda__d3ielc___1				Deinococcus-Thermus		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]		rRNA processing [GO:0006364]		cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2yveb1_d1t56a1__1			Actinobacteria	Actinobacteria	DNA binding [GO:0003677]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2yveb1_d5eyra1__1			Actinobacteria	Actinobacteria	DNA binding [GO:0003677]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]	DNA binding [GO:0003677]
d2yvjb__d1fqta___1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2yvlc__d4bnoa___1			Aquificae		tRNA (m1A) methyltransferase complex [GO:0031515]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]; tRNA methylation [GO:0030488]		tRNA methylation [GO:0030488]		tRNA (m1A) methyltransferase complex [GO:0031515]		tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]	
d2yvlc__d5k09l___1		Metazoa	Aquificae	Chordata	tRNA (m1A) methyltransferase complex [GO:0031515]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]; tRNA methylation [GO:0030488]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	tRNA methylation [GO:0030488]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	tRNA (m1A) methyltransferase complex [GO:0031515]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d2yvua__d2j45b2__1			Crenarchaeota	Deinococcus-Thermus	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]		signal recognition particle [GO:0048500]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d2yvya2_d2uv4a1__1		Metazoa	Deinococcus-Thermus	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; magnesium ion transmembrane transporter activity [GO:0015095]; protein homodimerization activity [GO:0042803]; magnesium ion transport [GO:0015693]	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; ADP binding [GO:0043531]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; cAMP-dependent protein kinase activity [GO:0004691]; cAMP-dependent protein kinase regulator activity [GO:0008603]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; cell cycle arrest [GO:0007050]; fatty acid biosynthetic process [GO:0006633]; import into nucleus [GO:0051170]; macroautophagy [GO:0016236]; positive regulation of gene expression [GO:0010628]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]; regulation of glycolytic process [GO:0006110]; regulation of macroautophagy [GO:0016241]; regulation of signal transduction by p53 class mediator [GO:1901796]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]	magnesium ion transport [GO:0015693]	cell cycle arrest [GO:0007050]; fatty acid biosynthetic process [GO:0006633]; import into nucleus [GO:0051170]; macroautophagy [GO:0016236]; positive regulation of gene expression [GO:0010628]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]; regulation of glycolytic process [GO:0006110]; regulation of macroautophagy [GO:0016241]; regulation of signal transduction by p53 class mediator [GO:1901796]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; magnesium ion transmembrane transporter activity [GO:0015095]; protein homodimerization activity [GO:0042803]	ADP binding [GO:0043531]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; cAMP-dependent protein kinase activity [GO:0004691]; cAMP-dependent protein kinase regulator activity [GO:0008603]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]
d2yw2a1_d3g8db1__1			Aquificae	Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2yw2a2_d5bphc2__1			Aquificae	Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]		cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2yw2b1_d1ce8a3__1			Aquificae	Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]		carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2yw2b3_d5mlka3__1			Aquificae	Actinobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionyl-CoA carboxylase activity [GO:0004658]; carbon fixation [GO:0015977]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	carbon fixation [GO:0015977]		acetyl-CoA carboxylase complex [GO:0009317]; cell wall [GO:0005618]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionyl-CoA carboxylase activity [GO:0004658]
d2yw6a__d5u1ba___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; efflux transmembrane transporter activity [GO:0015562]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	efflux transmembrane transporter activity [GO:0015562]
d2yw7a1_d3uoio___1			Actinobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2yw7b1_d4xkud___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d2yw7g1_d3ge4h___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2yw7g1_d4todb___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2yw7h1_d4zttb1__1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cellular iron ion homeostasis [GO:0006879]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2yw7i1_d4d8gd1__1			Actinobacteria	Chlamydiae	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	ribonucleoside-diphosphate reductase complex [GO:0005971]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2ywja__d1iphd1__1			Euryarchaeota	Proteobacteria	cytosol [GO:0005829]; glutaminase complex [GO:1903600]; glutaminase activity [GO:0004359]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutaminase activity [GO:0004359]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2ywka1_d5ddpc___1	Metazoa	Metazoa	Chordata	Chordata	nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; poly(U) RNA binding [GO:0008266]; protein homodimerization activity [GO:0042803]; single-stranded RNA binding [GO:0003727]; cell differentiation [GO:0030154]; cellular response to oxidative stress [GO:0034599]; mRNA processing [GO:0006397]; multicellular organism development [GO:0007275]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cell differentiation [GO:0030154]; cellular response to oxidative stress [GO:0034599]; mRNA processing [GO:0006397]; multicellular organism development [GO:0007275]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	poly(U) RNA binding [GO:0008266]; protein homodimerization activity [GO:0042803]; single-stranded RNA binding [GO:0003727]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]
d2ywvb__d1w2ca___1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [GO:0004639]; 'de novo' IMP biosynthetic process [GO:0006189]; cobalamin biosynthetic process [GO:0009236]	cytosol [GO:0005829]; dendritic spine [GO:0043197]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; inositol-1,4,5-trisphosphate 3-kinase activity [GO:0008440]; Rac GTPase binding [GO:0048365]; actin cytoskeleton organization [GO:0030036]; dendritic spine maintenance [GO:0097062]; inositol metabolic process [GO:0006020]; inositol phosphate biosynthetic process [GO:0032958]; inositol phosphate metabolic process [GO:0043647]; positive regulation of dendritic spine morphogenesis [GO:0061003]; regulation of synaptic plasticity [GO:0048167]; signal transduction [GO:0007165]	'de novo' IMP biosynthetic process [GO:0006189]; cobalamin biosynthetic process [GO:0009236]	actin cytoskeleton organization [GO:0030036]; dendritic spine maintenance [GO:0097062]; inositol metabolic process [GO:0006020]; inositol phosphate biosynthetic process [GO:0032958]; inositol phosphate metabolic process [GO:0043647]; positive regulation of dendritic spine morphogenesis [GO:0061003]; regulation of synaptic plasticity [GO:0048167]; signal transduction [GO:0007165]		cytosol [GO:0005829]; dendritic spine [GO:0043197]	ATP binding [GO:0005524]; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [GO:0004639]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; inositol-1,4,5-trisphosphate 3-kinase activity [GO:0008440]; Rac GTPase binding [GO:0048365]
d2ywxa__d4b4kb___1			Euryarchaeota	Firmicutes	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]
d2ywya__d1s7ua1__1	Metazoa	Metazoa	Chordata	Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2ywza__d2jcci2__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2yx9a2_d1ksib2__1		Viridiplantae	Actinobacteria	Streptophyta	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; oxidation-reduction process [GO:0055114]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; oxidation-reduction process [GO:0055114]			aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; diamine oxidase activity [GO:0052597]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d2yxea__d4gf5d___1			Euryarchaeota	Actinobacteria	cytoplasm [GO:0005737]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]; protein repair [GO:0030091]	O-methyltransferase activity [GO:0008171]	protein repair [GO:0030091]		cytoplasm [GO:0005737]		protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]	O-methyltransferase activity [GO:0008171]
d2yxeb__d2xvma1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]; protein repair [GO:0030091]	cytosol [GO:0005829]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; response to antibiotic [GO:0046677]; response to tellurium ion [GO:0046690]; response to toxic substance [GO:0009636]	protein repair [GO:0030091]	response to antibiotic [GO:0046677]; response to tellurium ion [GO:0046690]; response to toxic substance [GO:0009636]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]	S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d2yxma1_d2gsie2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; myofibril [GO:0030016]; myosin filament [GO:0032982]; actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]		cytosol [GO:0005829]; myofibril [GO:0030016]; myosin filament [GO:0032982]	extracellular region [GO:0005576]; membrane [GO:0016020]	actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d2yxva1_d1iluh___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2yxvb1_d4ko9d___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2yxvb2_d1ikop___1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	adherens junction [GO:0005912]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; ephrin receptor binding [GO:0046875]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; ephrin receptor signaling pathway [GO:0048013]; lymph vessel development [GO:0001945]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of neuron projection development [GO:0010977]; nephric duct morphogenesis [GO:0072178]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of neuron death [GO:1901216]; presynapse assembly [GO:0099054]; regulation of chemotaxis [GO:0050920]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; T cell costimulation [GO:0031295]; venous blood vessel morphogenesis [GO:0048845]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; ephrin receptor signaling pathway [GO:0048013]; lymph vessel development [GO:0001945]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of neuron projection development [GO:0010977]; nephric duct morphogenesis [GO:0072178]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of neuron death [GO:1901216]; presynapse assembly [GO:0099054]; regulation of chemotaxis [GO:0050920]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; T cell costimulation [GO:0031295]; venous blood vessel morphogenesis [GO:0048845]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	adherens junction [GO:0005912]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	ephrin receptor binding [GO:0046875]; signaling receptor binding [GO:0005102]
d2yxwa2_d1kbwb2__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cell outer membrane [GO:0009279]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2yxwb1_d2fjsa2__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2yy2b__d2qyla___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d2yy9b1_d2vpka1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; double-stranded telomeric DNA binding [GO:0003691]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]; positive regulation of transcription, DNA-templated [GO:0045893]; telomere maintenance via telomere lengthening [GO:0010833]	nucleoplasm [GO:0005654]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; zinc ion binding [GO:0008270]; cellular response to leukemia inhibitory factor [GO:1990830]; transcription, DNA-templated [GO:0006351]	positive regulation of transcription, DNA-templated [GO:0045893]; telomere maintenance via telomere lengthening [GO:0010833]	cellular response to leukemia inhibitory factor [GO:1990830]; transcription, DNA-templated [GO:0006351]	chromosome, telomeric region [GO:0000781]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	nucleoplasm [GO:0005654]	double-stranded telomeric DNA binding [GO:0003691]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; zinc ion binding [GO:0008270]
d2yyaa1_d1ce8e3__1			Aquificae	Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]		carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2yyba__d3wsic___1			Deinococcus-Thermus									
d2yyeb2_d5d9ub2__1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]; selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]
d2yyna__d4a9ma___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]; chromatin binding [GO:0003682]; estrogen response element binding [GO:0034056]; lysine-acetylated histone binding [GO:0070577]; nuclear receptor binding [GO:0016922]; p53 binding [GO:0002039]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription by RNA polymerase II [GO:0006366]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	cytosol [GO:0005829]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	chromatin binding [GO:0003682]; estrogen response element binding [GO:0034056]; lysine-acetylated histone binding [GO:0070577]; nuclear receptor binding [GO:0016922]; p53 binding [GO:0002039]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]
d2yyna__d5ktwb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]; chromatin binding [GO:0003682]; estrogen response element binding [GO:0034056]; lysine-acetylated histone binding [GO:0070577]; nuclear receptor binding [GO:0016922]; p53 binding [GO:0002039]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription by RNA polymerase II [GO:0006366]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytosol [GO:0005829]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; estrogen response element binding [GO:0034056]; lysine-acetylated histone binding [GO:0070577]; nuclear receptor binding [GO:0016922]; p53 binding [GO:0002039]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2yynb__d4o73a1__1	Metazoa		Chordata		cytosol [GO:0005829]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]; chromatin binding [GO:0003682]; estrogen response element binding [GO:0034056]; lysine-acetylated histone binding [GO:0070577]; nuclear receptor binding [GO:0016922]; p53 binding [GO:0002039]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription by RNA polymerase II [GO:0006366]		calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription by RNA polymerase II [GO:0006366]		cytosol [GO:0005829]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]		chromatin binding [GO:0003682]; estrogen response element binding [GO:0034056]; lysine-acetylated histone binding [GO:0070577]; nuclear receptor binding [GO:0016922]; p53 binding [GO:0002039]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	
d2yz7b__d4qsmc1__1		Metazoa	Proteobacteria	Chordata	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2yz7e__d1g0oa___1		Fungi	Proteobacteria	Ascomycota	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	tetrahydroxynaphthalene reductase activity [GO:0047039]; melanin biosynthetic process [GO:0042438]		melanin biosynthetic process [GO:0042438]			3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	tetrahydroxynaphthalene reductase activity [GO:0047039]
d2yz7h__d4uula1__1			Proteobacteria		3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]			3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]; nucleotide binding [GO:0000166]
d2yzbc1_d1r4ua2__1		Fungi	Actinobacteria	Ascomycota	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d2yzbc2_d4mb8a1__1		Metazoa	Actinobacteria	Chordata	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d2yzbf1_d2o9mf___1			Actinobacteria		urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]				urate oxidase activity [GO:0004846]	
d2yzbf2_d1fbxc___1			Actinobacteria	Proteobacteria	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d2yzbg1_d1xy3f2__1		Fungi	Actinobacteria	Ascomycota	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d2yzbg1_d2o9md___1			Actinobacteria		urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]				urate oxidase activity [GO:0004846]	
d2yzbh1_d2yzca2__1			Actinobacteria	Actinobacteria	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]			urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d2yzbh2_d2yzed1__1			Actinobacteria	Actinobacteria	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]			urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d2yzbh2_d5ll1g1__1		Metazoa	Actinobacteria	Chordata	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d2yzca2_d3qn0d___1			Actinobacteria	Proteobacteria	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	queuosine biosynthetic process [GO:0008616]			urate oxidase activity [GO:0004846]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d2yzcb1_d4r8xb1__1			Actinobacteria	Firmicutes	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]				urate oxidase activity [GO:0004846]	
d2yzcb2_d1j2gb2__1			Actinobacteria	Firmicutes	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]; allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]			urate oxidase activity [GO:0004846]	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]
d2yzcb2_d1n3rk___1			Actinobacteria	Proteobacteria	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d2yzcc1_d1dhna___1			Actinobacteria	Firmicutes	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]			urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]
d2yzcc1_d3pkfa1__1		Fungi	Actinobacteria	Ascomycota	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d2yzcc2_d2icqa2__1		Fungi	Actinobacteria	Ascomycota	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d2yzcd2_d1wpla___1		Metazoa	Actinobacteria	Chordata	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]
d2yzcf1_d1sqlb___1		Viridiplantae	Actinobacteria	Streptophyta	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]
d2yzch2_d1wm9b___1			Actinobacteria	Deinococcus-Thermus	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d2yzda1_d4r8xc1__1			Actinobacteria	Firmicutes	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]				urate oxidase activity [GO:0004846]	
d2yzdb1_d1fbxo___1			Actinobacteria	Proteobacteria	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d2yzdb2_d1n3ri___1			Actinobacteria	Proteobacteria	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d2yzdc1_d2dtte___1			Actinobacteria	Euryarchaeota	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	metal ion binding [GO:0046872]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]				urate oxidase activity [GO:0004846]	metal ion binding [GO:0046872]
d2yzdc2_d3lbga1__1		Fungi	Actinobacteria	Ascomycota	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d2yzdd2_d1u68a___1			Actinobacteria	Firmicutes	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]			urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]
d2yzeb1_d3r2ea1__1			Actinobacteria	Proteobacteria	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]			urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]
d2yzee1_d5ll1c2__1		Metazoa	Actinobacteria	Chordata	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d2yzee2_d2dhna___1			Actinobacteria	Firmicutes	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]			urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]
d2yzeg1_d2obad1__1			Actinobacteria	Proteobacteria	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]; queuosine biosynthetic process [GO:0008616]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	queuosine biosynthetic process [GO:0008616]			urate oxidase activity [GO:0004846]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; metal ion binding [GO:0046872]
d2yzeg2_d1uoxa2__1			Actinobacteria		urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]				urate oxidase activity [GO:0004846]	
d2yzha1_d3e3ea___1		Metazoa	Aquificae	Chordata	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	thioredoxin peroxidase activity [GO:0008379]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d2yzhb1_d2b5ya___1			Aquificae	Firmicutes	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	thioredoxin peroxidase activity [GO:0008379]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]
d2yzhd1_d3q19b1__1		Metazoa	Aquificae	Chordata	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	thioredoxin peroxidase activity [GO:0008379]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d2yzma1_d5d8dc1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2yzmb1_d5mf4f1__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d2yzna1_d1c3oa3__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2yzna1_d5bpfd1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2yznb1_d1keeg4__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d2yzrb__d3o06a___1		Fungi	Euryarchaeota	Ascomycota	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]		glutaminase complex [GO:1903600]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d2z02b__d4o7va___1			Euryarchaeota	Euryarchaeota	cytosol [GO:0005829]; ATP binding [GO:0005524]; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [GO:0004639]; 'de novo' IMP biosynthetic process [GO:0006189]; cobalamin biosynthetic process [GO:0009236]	ATP binding [GO:0005524]; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [GO:0004639]; 'de novo' IMP biosynthetic process [GO:0006189]; cobalamin biosynthetic process [GO:0009236]	'de novo' IMP biosynthetic process [GO:0006189]; cobalamin biosynthetic process [GO:0009236]	'de novo' IMP biosynthetic process [GO:0006189]; cobalamin biosynthetic process [GO:0009236]	cytosol [GO:0005829]		ATP binding [GO:0005524]; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [GO:0004639]	ATP binding [GO:0005524]; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [GO:0004639]
d2z06a__d3egga___1		Metazoa	Deinococcus-Thermus	Chordata	metal ion binding [GO:0046872]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	metal ion binding [GO:0046872]	cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]
d2z06b__d3k7vc___1		Metazoa	Deinococcus-Thermus	Chordata	metal ion binding [GO:0046872]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]		apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]		chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]	metal ion binding [GO:0046872]	GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]
d2z06d__d1utea___1		Metazoa	Deinococcus-Thermus	Chordata	metal ion binding [GO:0046872]	extracellular region [GO:0005576]; lysosome [GO:0005764]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]		bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]		extracellular region [GO:0005576]; lysosome [GO:0005764]	metal ion binding [GO:0046872]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]
d2z0ab__d3m8al1__1			Negarnaviricota	Negarnaviricota	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; RNA binding [GO:0003723]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; RNA binding [GO:0003723]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d2z0ad__d3rt3c___1		Metazoa	Negarnaviricota	Chordata	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; RNA binding [GO:0003723]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	RNA binding [GO:0003723]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2z0sa2_d2nn6g3__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA catabolic process [GO:0006401]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; RNA binding [GO:0003723]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; regulation of mRNA stability [GO:0043488]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA processing [GO:0006364]	RNA catabolic process [GO:0006401]	exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; regulation of mRNA stability [GO:0043488]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA processing [GO:0006364]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; exosome (RNase complex) [GO:0000178]; nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	poly(A) binding [GO:0008143]	RNA binding [GO:0003723]
d2z0ta__d1r6xa1__1		Fungi	Euryarchaeota	Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]		cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d2z12a__d1p2la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2z17a__d4nmvb___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleoplasm [GO:0005654]; regulation of cell adhesion [GO:0030155]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	regulation of cell adhesion [GO:0030155]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; nucleoplasm [GO:0005654]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]		ion channel binding [GO:0044325]
d2z18a__d4i0cb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2z1aa2_d3dsdb___1			Deinococcus-Thermus	Euryarchaeota	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; nucleotide catabolic process [GO:0009166]	3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]; double-strand break repair [GO:0006302]	nucleotide catabolic process [GO:0009166]	double-strand break repair [GO:0006302]			hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]
d2z1aa2_d4wwla1__1			Deinococcus-Thermus	Proteobacteria	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; nucleotide catabolic process [GO:0009166]	outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]	nucleotide catabolic process [GO:0009166]	nucleotide catabolic process [GO:0009166]		outer membrane-bounded periplasmic space [GO:0030288]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]
d2z1ia__d4fw1b1__1			Proteobacteria		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; reverse transcription [GO:0001171]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; reverse transcription [GO:0001171]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	cytoplasm [GO:0005737]	viral nucleocapsid [GO:0019013]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d2z1ib__d1c1aa2__1			Proteobacteria		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; reverse transcription [GO:0001171]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; reverse transcription [GO:0001171]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	cytoplasm [GO:0005737]	viral nucleocapsid [GO:0019013]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d2z1zb__d4xewb___1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	biotin biosynthetic process [GO:0009102]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]
d2z23a__d1b3ea___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transport [GO:0055085]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	transmembrane transport [GO:0055085]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d2z2ea__d4et9a___1	Metazoa	Metazoa	Chordata	Chordata	lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]; cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; metabolic process [GO:0008152]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]; metal ion binding [GO:0046872]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2z2fa__d1p56a___1	Metazoa		Chordata		lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; digestion [GO:0007586]; metabolic process [GO:0008152]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; digestion [GO:0007586]; metabolic process [GO:0008152]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2z2fa__d2lzha___1	Metazoa	Metazoa	Chordata	Chordata	lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; digestion [GO:0007586]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytolysis [GO:0019835]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; digestion [GO:0007586]; metabolic process [GO:0008152]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2z2jb__d4jc4a___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	cytoplasm [GO:0005737]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	aminoacyl-tRNA hydrolase activity [GO:0004045]	aminoacyl-tRNA hydrolase activity [GO:0004045]
d2z31a__d1jnhg1__1	Metazoa	Metazoa	Chordata	Chordata		plasma membrane [GO:0005886]				plasma membrane [GO:0005886]		
d2z31b__d5iuei2__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2z31c1_d2dqfd___1	Metazoa	Metazoa	Chordata	Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2z31d1_d4pb0l1__1	Metazoa	Metazoa	Chordata	Chordata								
d2z33a__d2ff4a1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	chromatin [GO:0000785]; nucleus [GO:0005634]; double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; histone binding [GO:0042393]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; G1 DNA damage checkpoint [GO:0044783]; intra-S DNA damage checkpoint [GO:0031573]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of DNA replication [GO:0008156]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]	phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; G1 DNA damage checkpoint [GO:0044783]; intra-S DNA damage checkpoint [GO:0031573]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of DNA replication [GO:0008156]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	chromatin [GO:0000785]; nucleus [GO:0005634]	bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; histone binding [GO:0042393]
d2z33a__d2z9ma___1			Proteobacteria		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]		phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	
d2z35a__d6b3sl1__1	Metazoa	Metazoa	Chordata	Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2z35b__d3l9rf___1	Metazoa	Metazoa	Chordata	Chordata		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]		
d2z37a__d2q9ea___1	Viridiplantae		Streptophyta		chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]		host cell cytoplasm [GO:0030430]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	lysozyme activity [GO:0003796]
d2z38a1_d2blya___1	Viridiplantae	Metazoa	Streptophyta	Chordata	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2z3aa__d3nzxr___1		Fungi	Firmicutes	Ascomycota	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2z3aa__d5m2bq___1		Fungi	Firmicutes	Ascomycota	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2z3af__d3dy3r___1		Fungi	Firmicutes	Ascomycota	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2z3ai__d5cz6g___1		Fungi	Firmicutes	Ascomycota	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2z3aj__d1e94d___1			Firmicutes	Proteobacteria	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	proteolysis involved in cellular protein catabolic process [GO:0051603]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]
d2z3aj__d2bjfa___1			Firmicutes	Firmicutes	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	choloylglycine hydrolase activity [GO:0045302]	proteolysis involved in cellular protein catabolic process [GO:0051603]		HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]		metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]	choloylglycine hydrolase activity [GO:0045302]
d2z3al__d4y8mw___1		Fungi	Firmicutes	Ascomycota	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2z3ba__d5lf4f___1		Metazoa	Firmicutes	Chordata	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	proteolysis involved in cellular protein catabolic process [GO:0051603]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2z3bl__d5laje___1		Fungi	Firmicutes	Ascomycota	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2z3fc1_d5bnxd___1	Fungi	Metazoa	Ascomycota	Chordata	nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; histone binding [GO:0042393]; chromatin assembly [GO:0031497]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromatin assembly [GO:0031497]; chromatin organization [GO:0006325]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	histone binding [GO:0042393]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2z3ga__d1thza2__1	Fungi	Metazoa	Ascomycota	Chordata	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	response to antibiotic [GO:0046677]	'de novo' IMP biosynthetic process [GO:0006189]		cytosol [GO:0005829]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d2z3gb__d3vm8a___1	Fungi	Metazoa	Ascomycota	Chordata	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; viral process [GO:0016032]	response to antibiotic [GO:0046677]	cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; viral process [GO:0016032]		cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d2z3gd__d2b0wb2__1	Fungi		Ascomycota		blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]				blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]	
d2z3id__d2iu0b2__1	Fungi	Metazoa	Ascomycota	Chordata	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]; 'de novo' IMP biosynthetic process [GO:0006189]	response to antibiotic [GO:0046677]	'de novo' IMP biosynthetic process [GO:0006189]		cytosol [GO:0005829]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]	IMP cyclohydrolase activity [GO:0003937]; phosphoribosylaminoimidazolecarboxamide formyltransferase activity [GO:0004643]; protein homodimerization activity [GO:0042803]
d2z3kb__d4r87b___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; leucyltransferase activity [GO:0008914]; transferase activity, transferring amino-acyl groups [GO:0016755]; protein catabolic process [GO:0030163]	cytoplasm [GO:0005737]; diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]; polyamine catabolic process [GO:0006598]	protein catabolic process [GO:0030163]	polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	leucyltransferase activity [GO:0008914]; transferase activity, transferring amino-acyl groups [GO:0016755]	diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]
d2z3pb__d4ygoa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; leucyltransferase activity [GO:0008914]; transferase activity, transferring amino-acyl groups [GO:0016755]; protein catabolic process [GO:0030163]	cytoplasm [GO:0005737]; diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]; polyamine catabolic process [GO:0006598]	protein catabolic process [GO:0030163]	polyamine catabolic process [GO:0006598]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	leucyltransferase activity [GO:0008914]; transferase activity, transferring amino-acyl groups [GO:0016755]	diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]
d2z3qc2_d1v7ny___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; interleukin-15 receptor activity [GO:0042010]; protein kinase binding [GO:0019901]; interleukin-15-mediated signaling pathway [GO:0035723]; positive regulation of phagocytosis [GO:0050766]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	interleukin-15-mediated signaling pathway [GO:0035723]; positive regulation of phagocytosis [GO:0050766]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine receptor activity [GO:0004896]; interleukin-15 receptor activity [GO:0042010]; protein kinase binding [GO:0019901]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]
d2z3re2_d2riga___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; interleukin-15 receptor activity [GO:0042010]; protein kinase binding [GO:0019901]; interleukin-15-mediated signaling pathway [GO:0035723]; positive regulation of phagocytosis [GO:0050766]	extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]; defense response to virus [GO:0051607]; immune response [GO:0006955]; positive regulation of autophagy [GO:0010508]; regulation of growth [GO:0040008]	interleukin-15-mediated signaling pathway [GO:0035723]; positive regulation of phagocytosis [GO:0050766]	defense response to virus [GO:0051607]; immune response [GO:0006955]; positive regulation of autophagy [GO:0010508]; regulation of growth [GO:0040008]	cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	cytokine receptor activity [GO:0004896]; interleukin-15 receptor activity [GO:0042010]; protein kinase binding [GO:0019901]	cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]
d2z3ua__d2fdva___1		Metazoa	Actinobacteria	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d2z3va__d5ol2b___1			Deinococcus-Thermus	Firmicutes	ATP binding [GO:0005524]	acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]					ATP binding [GO:0005524]	acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]
d2z42a1_d3vkmb1__1		Metazoa	Proteobacteria	Chordata	lyase activity [GO:0016829]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	lyase activity [GO:0016829]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d2z46e__d2pekc___1			Cyanobacteria	Cyanobacteria	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d2z48b2_d4qd2h1__1	Metazoa	Metazoa	Echinodermata	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]		adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]		actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d2z49a1_d2zqnb___1	Metazoa	Metazoa	Echinodermata	Annelida	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d2z49b1_d3ah2b2__1	Metazoa		Echinodermata		carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d2z49b1_d3rtjb1__1	Metazoa	Viridiplantae	Echinodermata	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		endoplasmic reticulum [GO:0005783]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2z4ki1_d2deia1__1				Euryarchaeota		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; galactokinase activity [GO:0004335]; galactose binding [GO:0005534]; magnesium ion binding [GO:0000287]; galactose metabolic process [GO:0006012]		galactose metabolic process [GO:0006012]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; galactokinase activity [GO:0004335]; galactose binding [GO:0005534]; magnesium ion binding [GO:0000287]
d2z4kq1_d1ph8a1__1				Ciliophora		nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]		telomere capping [GO:0016233]		nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]		protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d2z4ld1_d4j0qd2__1				Proteobacteria		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2z4lk1_d1kqsj___1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2z4lo1_d2avyk1__1												
d2z4mc2_d2uuac2__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2z4mi1_d1xnqi___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2z4mp1_d2uucp1__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d2z4mq1_d4a76a___1		Metazoa		Chordata		nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]						nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]
d2z4n61_d1ek8a___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		ribosomal large subunit binding [GO:0043023]
d2z4n61_d4gd1y1__1												
d2z4nd1_d4pc3a2__1				Proteobacteria		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2z4nl1_d1vq7o1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2z4qa2_d4l4ve2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2z54a__d5p1ra___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2z54b__d2o4sb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2z5da1_d4yc1a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]; autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]	calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]
d2z5pa__d3is7u___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2z5qa__d2jd8e___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]
d2z68b__d3hoka___1		Metazoa	Actinobacteria	Chordata	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]	heme oxidation [GO:0006788]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; cytokine-mediated signaling pathway [GO:0019221]; endothelial cell proliferation [GO:0001935]; erythrocyte homeostasis [GO:0034101]; excretion [GO:0007588]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246]		caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular space [GO:0005615]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]
d2z6ca__d2hv1a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vacuole [GO:0005773]; ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; mRNA binding [GO:0003729]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; chloroplast accumulation movement [GO:0009904]; chloroplast avoidance movement [GO:0009903]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-chromophore linkage [GO:0018298]; regulation of proton transport [GO:0010155]; regulation of stomatal movement [GO:0010119]; response to blue light [GO:0009637]	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]; aryl hydrocarbon receptor binding [GO:0017162]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; nuclear receptor activity [GO:0004879]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; cell differentiation [GO:0030154]; embryonic placenta development [GO:0001892]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; xenobiotic metabolic process [GO:0006805]	chloroplast accumulation movement [GO:0009904]; chloroplast avoidance movement [GO:0009903]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; protein phosphorylation [GO:0006468]; regulation of proton transport [GO:0010155]; regulation of stomatal movement [GO:0010119]; response to blue light [GO:0009637]	cell differentiation [GO:0030154]; embryonic placenta development [GO:0001892]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vacuole [GO:0005773]	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase II transcription factor complex [GO:0090575]	ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; mRNA binding [GO:0003729]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	aryl hydrocarbon receptor binding [GO:0017162]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; nuclear receptor activity [GO:0004879]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]
d2z6kd__d1ah9a___1	Metazoa		Chordata	Proteobacteria	DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; single-stranded DNA binding [GO:0003697]; base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	cytosol [GO:0005829]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation initiation factor activity [GO:0003743]	base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell population proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]		DNA replication factor A complex [GO:0005662]; nucleoplasm [GO:0005654]; site of double-strand break [GO:0035861]	cytosol [GO:0005829]	damaged DNA binding [GO:0003684]; single-stranded DNA binding [GO:0003697]	ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation initiation factor activity [GO:0003743]
d2z6ma__d1f30i___1	Metazoa		Chordata	Proteobacteria	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2z6ma__d2ib0b___1	Metazoa		Chordata	Actinobacteria	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	
d2z6mb__d5u1bb___1	Metazoa		Chordata	Proteobacteria	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; efflux transmembrane transporter activity [GO:0015562]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	efflux transmembrane transporter activity [GO:0015562]
d2z6mh__d5gu0x___1	Metazoa	Metazoa	Chordata	Chordata	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d2z6oa__d2c4oc___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; UFM1 conjugating enzyme activity [GO:0061657]; UFM1 transferase activity [GO:0071568]; brain development [GO:0007420]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; response to endoplasmic reticulum stress [GO:0034976]		brain development [GO:0007420]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; response to endoplasmic reticulum stress [GO:0034976]		extracellular exosome [GO:0070062]		UFM1 conjugating enzyme activity [GO:0061657]; UFM1 transferase activity [GO:0071568]	
d2z6sa__d2bv8a___1	Metazoa		Chordata	Rhodophyta	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2z6sa__d2pghb___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2z6ua__d1fjxa___1			Proteobacteria	Proteobacteria	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]	DNA restriction-modification system [GO:0009307]			DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d2z6wb__d2hq6a1__1	Metazoa	Metazoa	Chordata	Chordata	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654]; U2-type precatalytic spliceosome [GO:0071005]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]	catalytic step 2 spliceosome [GO:0071013]; nucleoplasm [GO:0005654]; U2-type precatalytic spliceosome [GO:0071005]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2z79a__d1qotd___1		Viridiplantae	Firmicutes	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d2z7aa__d2f86j___1		Metazoa	Actinobacteria	Nematoda (roundworms)	isomerase activity [GO:0016853]; protein homodimerization activity [GO:0042803]; sterol binding [GO:0032934]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]		MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]		axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	isomerase activity [GO:0016853]; protein homodimerization activity [GO:0042803]; sterol binding [GO:0032934]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d2z7ca__d4z9ea___1			Euryarchaeota	Euryarchaeota	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]			chromosome [GO:0005694]; cytoplasm [GO:0005737]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]
d2z7ga__d4e3tb___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]; adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	plasma membrane [GO:0005886]; aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]; catabolic process [GO:0009056]	adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	catabolic process [GO:0009056]	cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]	plasma membrane [GO:0005886]	adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]	aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]
d2z7ub__d1n18b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d2z7yb__d4a7gf___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d2z85a__d2bkma___1	Metazoa		Mollusca	Firmicutes	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]			cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d2z8vd1_d2r2eb2__1			Apicomplexa		apical complex [GO:0020007]; membrane [GO:0016020]; microneme [GO:0020009]; host cell surface binding [GO:0046812]; entry into host cell [GO:0030260]; pathogenesis [GO:0009405]		entry into host cell [GO:0030260]; pathogenesis [GO:0009405]		apical complex [GO:0020007]; membrane [GO:0016020]; microneme [GO:0020009]		host cell surface binding [GO:0046812]	
d2z8wc1_d4ma7l1__1	Metazoa	Metazoa	Chordata	Chordata		anchored component of membrane [GO:0031225]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of catalytic activity [GO:0043086]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization [GO:0032880]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to oxidative stress [GO:0006979]		activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of catalytic activity [GO:0043086]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of cell death [GO:0010942]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization [GO:0032880]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to oxidative stress [GO:0006979]		anchored component of membrane [GO:0031225]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d2z8wd1_d3b2vh1__1	Metazoa	Metazoa	Chordata	Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d2z90a__d4evba___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2z90a__d4n83e___1			Actinobacteria	Firmicutes	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d2z91b1_d1rzkh2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d2z91b2_d4r7db1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2z92b2_d4ktdl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2z93d1_d2iant2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2z95c__d2nsdb___1			Aquificae	Actinobacteria	cytoplasm [GO:0005737]; GDP-mannose 4,6-dehydratase activity [GO:0008446]; NADP+ binding [GO:0070401]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	GDP-mannose 4,6-dehydratase activity [GO:0008446]; NADP+ binding [GO:0070401]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d2z9hb2_d5l37d___1			Proteobacteria	Actinobacteria	cellular response to DNA damage stimulus [GO:0006974]; ethanolamine catabolic process [GO:0046336]		cellular response to DNA damage stimulus [GO:0006974]; ethanolamine catabolic process [GO:0046336]					
d2z9hd2_d4n8fa___1			Proteobacteria	Cyanobacteria	cellular response to DNA damage stimulus [GO:0006974]; ethanolamine catabolic process [GO:0046336]		cellular response to DNA damage stimulus [GO:0006974]; ethanolamine catabolic process [GO:0046336]					
d2z9ja__d2zprb___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]		cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]		3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d2z9ja__d5bpea___1					cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	cysteine-type endopeptidase activity [GO:0004197]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]		cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]		3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	cysteine-type endopeptidase activity [GO:0004197]
d2z9ka__d2y81a___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d2z9kb__d4crda___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d2z9se__d1j08f2__1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]; heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]	cell [GO:0005623]	heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d2z9sg__d2r5ga1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]; heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; intracellular [GO:0005622]; nucleus [GO:0005634]; chloride channel activity [GO:0005254]; glutathione peroxidase activity [GO:0004602]; voltage-gated ion channel activity [GO:0005244]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of binding [GO:0051099]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of binding [GO:0051099]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; signal transduction [GO:0007165]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]	chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; intracellular [GO:0005622]; nucleus [GO:0005634]	heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	chloride channel activity [GO:0005254]; glutathione peroxidase activity [GO:0004602]; voltage-gated ion channel activity [GO:0005244]
d2z9sh__d4oo4b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]; heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d2z9sj__d2pukc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]; heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; chloroplast [GO:0009507]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]	cell [GO:0005623]; chloroplast [GO:0009507]	heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	protein disulfide oxidoreductase activity [GO:0015035]
d2za4a__d1t2ia___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]		endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d2za4a__d3wr2f___1		Fungi	Firmicutes	Basidiomycota	cytoplasm [GO:0005737]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cytoplasm [GO:0005737]			endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d2za5a__d2amdb1__1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2za5b__d1gdqa___1	Metazoa	Fungi	Chordata	Ascomycota	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	proteolysis [GO:0006508]		collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase activity [GO:0004252]
d2za5b__d2fmja___1	Metazoa		Chordata	Actinobacteria	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	serine-type endopeptidase activity [GO:0004252]	proteolysis [GO:0006508]		collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]		serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase activity [GO:0004252]
d2za5c__d1p9ub___1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2za6a__d3uoid___1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2za7a__d2iy4k___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d2za8a__d5d8si___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d2zaba__d2dtyd___1		Viridiplantae	Proteobacteria	Streptophyta	lyase activity [GO:0016829]	carbohydrate binding [GO:0030246]					lyase activity [GO:0016829]	carbohydrate binding [GO:0030246]
d2zaca__d3galb___1		Metazoa	Proteobacteria	Chordata	lyase activity [GO:0016829]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	lyase activity [GO:0016829]	carbohydrate binding [GO:0030246]
d2zafb1_d1siqa1__1	Fungi	Metazoa	Ascomycota	Chordata	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA dehydrogenase activity [GO:0004361]; glutaryl-CoA hydrolase activity [GO:0044466]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lysine catabolic process [GO:0006554]; tryptophan metabolic process [GO:0006568]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lysine catabolic process [GO:0006554]; tryptophan metabolic process [GO:0006568]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA dehydrogenase activity [GO:0004361]; glutaryl-CoA hydrolase activity [GO:0044466]
d2zafc1_d3fcja2__1	Fungi	Fungi	Ascomycota	Ascomycota	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]			FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d2zata__d1r72c4__1	Metazoa		Chordata		mitochondrion [GO:0005739]; peroxisome [GO:0005777]; 3-keto sterol reductase activity [GO:0000253]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; retinal dehydrogenase activity [GO:0001758]; oxidation-reduction process [GO:0055114]; retinal metabolic process [GO:0042574]		oxidation-reduction process [GO:0055114]; retinal metabolic process [GO:0042574]		mitochondrion [GO:0005739]; peroxisome [GO:0005777]		3-keto sterol reductase activity [GO:0000253]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; retinal dehydrogenase activity [GO:0001758]	
d2zatc__d3rbxb1__1	Metazoa		Chordata	Euryarchaeota	mitochondrion [GO:0005739]; peroxisome [GO:0005777]; 3-keto sterol reductase activity [GO:0000253]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; retinal dehydrogenase activity [GO:0001758]; oxidation-reduction process [GO:0055114]; retinal metabolic process [GO:0042574]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	oxidation-reduction process [GO:0055114]; retinal metabolic process [GO:0042574]	potassium ion transport [GO:0006813]	mitochondrion [GO:0005739]; peroxisome [GO:0005777]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	3-keto sterol reductase activity [GO:0000253]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; retinal dehydrogenase activity [GO:0001758]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2zatd__d4ro0b1__1	Metazoa		Chordata	Euryarchaeota	mitochondrion [GO:0005739]; peroxisome [GO:0005777]; 3-keto sterol reductase activity [GO:0000253]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; retinal dehydrogenase activity [GO:0001758]; oxidation-reduction process [GO:0055114]; retinal metabolic process [GO:0042574]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	oxidation-reduction process [GO:0055114]; retinal metabolic process [GO:0042574]	potassium ion transport [GO:0006813]	mitochondrion [GO:0005739]; peroxisome [GO:0005777]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	3-keto sterol reductase activity [GO:0000253]; carbonyl reductase (NADPH) activity [GO:0004090]; identical protein binding [GO:0042802]; retinal dehydrogenase activity [GO:0001758]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d2zaua2_d5cm7b2__1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]; selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]
d2zaub2_d5cc8b2__1			Aquificae		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]; selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]		selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]	
d2zawa__d2y46a___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2zbha__d3fvib___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]; bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	extracellular region [GO:0005576]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]
d2zblb1_d1ayxa___1		Fungi	Proteobacteria	Ascomycota	sulfoquinovose isomerase activity [GO:0061593]; 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde [GO:0061720]	glucan 1,4-alpha-glucosidase activity [GO:0004339]; polysaccharide catabolic process [GO:0000272]	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde [GO:0061720]	polysaccharide catabolic process [GO:0000272]			sulfoquinovose isomerase activity [GO:0061593]	glucan 1,4-alpha-glucosidase activity [GO:0004339]
d2zblc1_d1fboa___1			Proteobacteria	Firmicutes	sulfoquinovose isomerase activity [GO:0061593]; 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde [GO:0061720]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde [GO:0061720]	cellulose catabolic process [GO:0030245]			sulfoquinovose isomerase activity [GO:0061593]	cellulase activity [GO:0008810]
d2zblf1_d1ksca1__1		Metazoa	Proteobacteria	Arthropoda	sulfoquinovose isomerase activity [GO:0061593]; 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde [GO:0061720]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde [GO:0061720]	cellulose catabolic process [GO:0030245]			sulfoquinovose isomerase activity [GO:0061593]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]
d2zboe__d2dgea___1		Viridiplantae		Streptophyta	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	chloroplast thylakoid lumen [GO:0009543]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem I [GO:0009773]		photosynthetic electron transport in photosystem I [GO:0009773]		chloroplast thylakoid lumen [GO:0009543]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d2zbta__d4jdyc___1			Deinococcus-Thermus	Actinobacteria	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; pyridoxal phosphate biosynthetic process [GO:0042823]	plasma membrane [GO:0005886]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]	pyridoxal phosphate biosynthetic process [GO:0042823]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]		plasma membrane [GO:0005886]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d2zc8b2_d4h83b2__1			Deinococcus-Thermus	Actinobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	metal ion binding [GO:0046872]	menaquinone biosynthetic process [GO:0009234]				hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]
d2zcca__d3m62b___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleotide-excision repair factor 2 complex [GO:0000111]; proteasome complex [GO:0000502]; damaged DNA binding [GO:0003684]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deglycosylation [GO:0006517]; ubiquitin-dependent ERAD pathway [GO:0030433]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deglycosylation [GO:0006517]; ubiquitin-dependent ERAD pathway [GO:0030433]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleotide-excision repair factor 2 complex [GO:0000111]; proteasome complex [GO:0000502]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	damaged DNA binding [GO:0003684]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]
d2zccc__d5w8td___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2zchl2_d5gznl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d2zchp__d2p95a___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d2zcwa2_d4n9id1__1			Deinococcus-Thermus	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; protein homodimerization activity [GO:0042803]; positive regulation of transcription, DNA-templated [GO:0045893]; response to oxidative stress [GO:0006979]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	positive regulation of transcription, DNA-templated [GO:0045893]; response to oxidative stress [GO:0006979]				DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; protein homodimerization activity [GO:0042803]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d2zcyc__d5d0ta___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2zcyd__d5lexw___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2zcye__d3bdmb___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2zcyi__d1ajp.1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	periplasmic space [GO:0042597]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]
d2zcyk__d1ofea3__1	Fungi		Ascomycota	Cyanobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	3 iron, 4 sulfur cluster binding [GO:0051538]; glutamate synthase (ferredoxin) activity [GO:0016041]; metal ion binding [GO:0046872]; glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	3 iron, 4 sulfur cluster binding [GO:0051538]; glutamate synthase (ferredoxin) activity [GO:0016041]; metal ion binding [GO:0046872]
d2zcyn__d5l5dy___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2zcyr__d4qz6h___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2zcyu__d4qvlq___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2zcyw__d4r02a___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2zcyx__d3tddv___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d2zdda__d3pg4a1__1				Proteobacteria		periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2zddd__d5le1a___1				Proteobacteria		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d2zdeb__d3iofa___1				Proteobacteria		periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2zdfb__d4dilb1__1				Thermotogae		electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]						electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d2zdfc__d3ieka___1				Deinococcus-Thermus		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]		rRNA processing [GO:0006364]		cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2zdfc__d4tz9a1__1				Proteobacteria		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d2zdfd__d2zdwa___1												
d2zdfd__d3knsc___1				Firmicutes		periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2zdga1_d2v59b1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2zdgb1_d3rv3b1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d2zdgc1_d3v4zb1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d2zdgd1_d1uc9b1__1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]
d2zdhc1_d4o2af1__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d2zdqb1_d1m0wb1__1		Fungi	Deinococcus-Thermus	Ascomycota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; glutathione binding [GO:0043295]; glutathione synthase activity [GO:0004363]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; glutathione biosynthetic process [GO:0006750]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	glutathione biosynthetic process [GO:0006750]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutathione binding [GO:0043295]; glutathione synthase activity [GO:0004363]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]
d2zdra1_d4ipja2__1			Proteobacteria	Proteobacteria	catalytic activity [GO:0003824]; carbohydrate biosynthetic process [GO:0016051]	catalytic activity [GO:0003824]; carbohydrate biosynthetic process [GO:0016051]	carbohydrate biosynthetic process [GO:0016051]	carbohydrate biosynthetic process [GO:0016051]			catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d2zdwb__d4eyla1__1				Proteobacteria		periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d2zdwd__d1e5da2__1				Proteobacteria		electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; respiratory electron transport chain [GO:0022904]		respiratory electron transport chain [GO:0022904]				electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d2zdwd__d3ie0d___1				Deinococcus-Thermus		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]		rRNA processing [GO:0006364]		cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d2ze0a2_d1g5aa1__1			Firmicutes	Proteobacteria	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	amylosucrase activity [GO:0047669]
d2zebc__d5fx6a___1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2zecb__d1fiz.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	acrosomal matrix [GO:0043159]; protein-containing complex [GO:0032991]; amidase activity [GO:0004040]; drug binding [GO:0008144]; fucose binding [GO:0042806]; mannose binding [GO:0005537]; serine-type endopeptidase activity [GO:0004252]; acrosome reaction [GO:0007340]; activation of adenylate cyclase activity [GO:0007190]; single fertilization [GO:0007338]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	acrosome reaction [GO:0007340]; activation of adenylate cyclase activity [GO:0007190]; single fertilization [GO:0007338]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	acrosomal matrix [GO:0043159]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	amidase activity [GO:0004040]; drug binding [GO:0008144]; fucose binding [GO:0042806]; mannose binding [GO:0005537]; serine-type endopeptidase activity [GO:0004252]
d2zeqa2_d5ms2b___1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular vesicle [GO:0097708]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; mitochondrion-derived vesicle [GO:0099073]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; ubiquitin ligase complex [GO:0000151]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; chaperone binding [GO:0051087]; cullin family protein binding [GO:0097602]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; F-box domain binding [GO:1990444]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; Hsp70 protein binding [GO:0030544]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; tubulin binding [GO:0015631]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-specific protease binding [GO:1990381]; adult locomotory behavior [GO:0008344]; aggresome assembly [GO:0070842]; autophagy of mitochondrion [GO:0000422]; cellular protein catabolic process [GO:0044257]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to L-glutamate [GO:1905232]; cellular response to toxic substance [GO:0097237]; dopamine metabolic process [GO:0042417]; dopamine uptake involved in synaptic transmission [GO:0051583]; free ubiquitin chain polymerization [GO:0010994]; learning [GO:0007612]; locomotory behavior [GO:0007626]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; mitochondrion to lysosome transport [GO:0099074]; mitophagy [GO:0000423]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell death [GO:0060548]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903382]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of exosomal secretion [GO:1903542]; negative regulation of gene expression [GO:0010629]; negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676]; negative regulation of intralumenal vesicle formation [GO:1905366]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of JNK cascade [GO:0046329]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of primary amine oxidase activity [GO:1902283]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of spontaneous neurotransmitter secretion [GO:1904049]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron cellular homeostasis [GO:0070050]; norepinephrine metabolic process [GO:0042415]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of dendrite extension [GO:1903861]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of mitophagy [GO:1901526]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of neurotransmitter uptake [GO:0051582]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein localization to membrane [GO:1905477]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K6-linked ubiquitination [GO:0085020]; protein K63-linked ubiquitination [GO:0070534]; protein localization to mitochondrion [GO:0070585]; protein metabolic process [GO:0019538]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of dopamine metabolic process [GO:0042053]; regulation of gene expression [GO:0010468]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein stability [GO:0031647]; regulation of protein ubiquitination [GO:0031396]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; startle response [GO:0001964]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; ubiquitin-dependent protein catabolic process [GO:0006511]; zinc ion homeostasis [GO:0055069]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	adult locomotory behavior [GO:0008344]; aggresome assembly [GO:0070842]; autophagy of mitochondrion [GO:0000422]; cellular protein catabolic process [GO:0044257]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to L-glutamate [GO:1905232]; cellular response to toxic substance [GO:0097237]; dopamine metabolic process [GO:0042417]; dopamine uptake involved in synaptic transmission [GO:0051583]; free ubiquitin chain polymerization [GO:0010994]; learning [GO:0007612]; locomotory behavior [GO:0007626]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; mitochondrion to lysosome transport [GO:0099074]; mitophagy [GO:0000423]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell death [GO:0060548]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903382]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of exosomal secretion [GO:1903542]; negative regulation of gene expression [GO:0010629]; negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676]; negative regulation of intralumenal vesicle formation [GO:1905366]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of JNK cascade [GO:0046329]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of primary amine oxidase activity [GO:1902283]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of spontaneous neurotransmitter secretion [GO:1904049]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron cellular homeostasis [GO:0070050]; norepinephrine metabolic process [GO:0042415]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of dendrite extension [GO:1903861]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of mitophagy [GO:1901526]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of neurotransmitter uptake [GO:0051582]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein localization to membrane [GO:1905477]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein localization to mitochondrion [GO:0070585]; protein metabolic process [GO:0019538]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of dopamine metabolic process [GO:0042053]; regulation of gene expression [GO:0010468]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein stability [GO:0031647]; regulation of protein ubiquitination [GO:0031396]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; startle response [GO:0001964]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; ubiquitin-dependent protein catabolic process [GO:0006511]; zinc ion homeostasis [GO:0055069]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	aggresome [GO:0016235]; axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular vesicle [GO:0097708]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; mitochondrion-derived vesicle [GO:0099073]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; ubiquitin ligase complex [GO:0000151]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; chaperone binding [GO:0051087]; cullin family protein binding [GO:0097602]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; F-box domain binding [GO:1990444]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; Hsp70 protein binding [GO:0030544]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; phospholipase binding [GO:0043274]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; tubulin binding [GO:0015631]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-specific protease binding [GO:1990381]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d2zf5y2_d5aqpa2__1		Metazoa	Euryarchaeota	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d2zfba__d1yhrc___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2zfba__d2zs0d___1	Metazoa	Metazoa	Chordata	Annelida	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2zfbb__d1y4vd___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2zfda__d5f6ta___1	Viridiplantae	Metazoa	Streptophyta	Mollusca	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; ATP binding [GO:0005524]; kinase binding [GO:0019900]; protein serine/threonine kinase activity [GO:0004674]; response to abscisic acid [GO:0009737]; response to cold [GO:0009409]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to water deprivation [GO:0009414]; signal transduction [GO:0007165]	metal ion binding [GO:0046872]	response to abscisic acid [GO:0009737]; response to cold [GO:0009409]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to water deprivation [GO:0009414]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasmodesma [GO:0009506]; vacuole [GO:0005773]		ATP binding [GO:0005524]; kinase binding [GO:0019900]; protein serine/threonine kinase activity [GO:0004674]	metal ion binding [GO:0046872]
d2zfhd__d3gsdb___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; membrane [GO:0016020]; copper ion binding [GO:0005507]; enzyme binding [GO:0019899]; protein localization [GO:0008104]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; response to metal ion [GO:0010038]	protein localization [GO:0008104]; response to metal ion [GO:0010038]	response to metal ion [GO:0010038]	extracellular exosome [GO:0070062]; membrane [GO:0016020]	cytoplasm [GO:0005737]	copper ion binding [GO:0005507]; enzyme binding [GO:0019899]	copper ion binding [GO:0005507]
d2zfta__d3sv8a___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2zfzd__d1xxca___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]
d2zfzf__d1xxbb___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]
d2zgaa__d5ahab___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2zgha__d2vvua___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; membrane [GO:0016020]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cytolysis [GO:0019835]; innate immune response [GO:0045087]; T cell mediated cytotoxicity [GO:0001913]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytolysis [GO:0019835]; innate immune response [GO:0045087]; T cell mediated cytotoxicity [GO:0001913]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; membrane [GO:0016020]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d2zgja__d1a1qa___1	Metazoa		Chordata		extracellular region [GO:0005576]; membrane [GO:0016020]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cytolysis [GO:0019835]; innate immune response [GO:0045087]; T cell mediated cytotoxicity [GO:0001913]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytolysis [GO:0019835]; innate immune response [GO:0045087]; T cell mediated cytotoxicity [GO:0001913]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2zgka__d4r9ba___1	Fungi	Metazoa	Basidiomycota	Chordata	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d2zgla1_d5duvc___1	Fungi	Metazoa	Basidiomycota	Chordata	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	cell adhesion [GO:0007155]		collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2zgmb1_d1i1ea1__1	Fungi		Basidiomycota	Firmicutes	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d2zgmb1_d1w2tf1__1	Fungi		Basidiomycota	Thermotogae	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	carbohydrate metabolic process [GO:0005975]			deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	beta-fructofuranosidase activity [GO:0004564]
d2zgna__d3pvog___1	Fungi	Metazoa	Basidiomycota	Chordata	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d2zgob1_d2exkd1__1	Fungi		Basidiomycota	Firmicutes	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	carbohydrate metabolic process [GO:0005975]			deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d2zgpa__d2r1dd1__1	Fungi	Metazoa	Basidiomycota	Chordata	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]		axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]
d2zgsa__d2np0a1__1	Fungi		Basidiomycota	Firmicutes	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d2zgyb2_d4ydud2__1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; plasmid partitioning [GO:0030541]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	plasmid partitioning [GO:0030541]	tRNA threonylcarbamoyladenosine modification [GO:0002949]		cytosol [GO:0005829]	identical protein binding [GO:0042802]	identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]
d2zgza1_d3ldpb2__1		Metazoa	Proteobacteria	Chordata	identical protein binding [GO:0042802]; plasmid partitioning [GO:0030541]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	plasmid partitioning [GO:0030541]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	identical protein binding [GO:0042802]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d2zgza2_d4fpbb2__1		Metazoa	Proteobacteria	Chordata	identical protein binding [GO:0042802]; plasmid partitioning [GO:0030541]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	plasmid partitioning [GO:0030541]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]		cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d2zgzb2_d5fpea2__1		Metazoa	Proteobacteria	Chordata	identical protein binding [GO:0042802]; plasmid partitioning [GO:0030541]	blood microparticle [GO:0072562]; CatSper complex [GO:0036128]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; meiotic spindle [GO:0072687]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptonemal complex [GO:0000795]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; glycolipid binding [GO:0051861]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; tau protein binding [GO:0048156]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein phosphorylation [GO:0001934]; protein refolding [GO:0042026]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex disassembly [GO:0070194]; vesicle-mediated transport [GO:0016192]	plasmid partitioning [GO:0030541]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein phosphorylation [GO:0001934]; protein refolding [GO:0042026]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex disassembly [GO:0070194]; vesicle-mediated transport [GO:0016192]		blood microparticle [GO:0072562]; CatSper complex [GO:0036128]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; meiotic spindle [GO:0072687]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptonemal complex [GO:0000795]	identical protein binding [GO:0042802]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; glycolipid binding [GO:0051861]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; tau protein binding [GO:0048156]; unfolded protein binding [GO:0051082]
d2zh4a1_d2q66a1__1		Fungi	Euryarchaeota	Ascomycota	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]		mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d2zh5a1_d4xq7a2__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; RNA binding [GO:0003723]; thyroid hormone receptor binding [GO:0046966]; transferase activity [GO:0016740]; defense response to virus [GO:0051607]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of viral genome replication [GO:0045071]; regulation of ribonuclease activity [GO:0060700]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	defense response to virus [GO:0051607]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of viral genome replication [GO:0045071]; regulation of ribonuclease activity [GO:0060700]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; double-stranded RNA binding [GO:0003725]; RNA binding [GO:0003723]; thyroid hormone receptor binding [GO:0046966]; transferase activity [GO:0016740]
d2zh6a2_d2fmsa3__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d2zh7a1_d4k8vd2__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immune response [GO:0050776]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]; regulation of type I interferon production [GO:0032479]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immune response [GO:0050776]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]; regulation of type I interferon production [GO:0032479]		cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]
d2zh7a2_d3uxna3__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d2zh8a2_d9icoa4__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d2zh9a1_d4k8va2__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immune response [GO:0050776]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]; regulation of type I interferon production [GO:0032479]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immune response [GO:0050776]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]; regulation of type I interferon production [GO:0032479]		cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]
d2zh9a2_d3k75e2__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d2zhaa1_d4jlza2__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]		cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]
d2zhaa2_d4k4hi3__1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]		nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d2zhba2_d5oolu___1		Metazoa	Euryarchaeota	Chordata	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412]		mitochondrial inner membrane [GO:0005743]; mitochondrial large ribosomal subunit [GO:0005762]; mitochondrial small ribosomal subunit [GO:0005763]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]	RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]
d2zhda__d1mzda___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]	digestion [GO:0007586]; proteolysis [GO:0006508]	negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2zhda__d3i78a___1	Metazoa		Chordata	Actinobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]		endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d2zhia__d1hvea___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; epithelial cell differentiation [GO:0030855]; exocytosis [GO:0006887]; Notch signaling pathway [GO:0007219]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; exocytosis [GO:0006887]; Notch signaling pathway [GO:0007219]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]
d2zhja__d1haka___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; epithelial cell differentiation [GO:0030855]; exocytosis [GO:0006887]; Notch signaling pathway [GO:0007219]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium-dependent phospholipid binding [GO:0005544]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]; blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; exocytosis [GO:0006887]; Notch signaling pathway [GO:0007219]	blood coagulation [GO:0007596]; cellular response to gonadotropin-releasing hormone [GO:0097211]; cellular response to lead ion [GO:0071284]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood coagulation [GO:0030195]; negative regulation of prolactin secretion [GO:1902721]; negative regulation of sequestering of calcium ion [GO:0051283]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; regulation of flagellated sperm motility [GO:1901317]; response to calcium ion [GO:0051592]; response to organic substance [GO:0010033]; response to thyroid hormone [GO:0097066]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endothelial microparticle [GO:0072563]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; intracellular [GO:0005622]; membrane [GO:0016020]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; heparin binding [GO:0008201]; peptide hormone binding [GO:0017046]; phospholipase inhibitor activity [GO:0004859]; phospholipid binding [GO:0005543]; receptor tyrosine kinase binding [GO:0030971]
d2zhla__d4zzva___1	Metazoa	Fungi	Chordata	Ascomycota	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	cellulose catabolic process [GO:0030245]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2zhlc__d4ym0c___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]; cell adhesion [GO:0007155]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	cell adhesion [GO:0007155]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d2zhld__d1juid___1	Metazoa	Viridiplantae	Chordata	Streptophyta	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d2zhld__d3c2uc2__1	Metazoa		Chordata	Firmicutes	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	carbohydrate metabolic process [GO:0005975]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d2zhmc__d1uypd1__1	Metazoa		Chordata	Thermotogae	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	carbohydrate metabolic process [GO:0005975]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	beta-fructofuranosidase activity [GO:0004564]
d2zhna__d2iwgb1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2zhna__d4hl0a2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	carbohydrate binding [GO:0030246]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]
d2zhpa__d1nkib___1			Actinobacteria	Proteobacteria	drug binding [GO:0008144]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; metal ion binding [GO:0046872]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]	drug binding [GO:0008144]	glutathione transferase activity [GO:0004364]; metal ion binding [GO:0046872]
d2zhxk__d5aysa1__1			Actinobacteria	Firmicutes	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	metal ion binding [GO:0046872]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]		mitochondrion [GO:0005739]; nucleus [GO:0005634]		uracil DNA N-glycosylase activity [GO:0004844]	metal ion binding [GO:0046872]
d2zhxm__d1lqga___1			Actinobacteria	Proteobacteria	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d2zhya__d2g2da___1			Proteobacteria	Actinobacteria	ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]; cobalamin biosynthetic process [GO:0009236]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]; cobalamin biosynthetic process [GO:0009236]; porphyrin-containing compound biosynthetic process [GO:0006779]	cobalamin biosynthetic process [GO:0009236]	cobalamin biosynthetic process [GO:0009236]; porphyrin-containing compound biosynthetic process [GO:0006779]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]	ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]
d2zi8a1_d3ojjd2__1			Actinobacteria	Actinobacteria	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity [GO:0047071]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; aromatic compound catabolic process [GO:0019439]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; response to cholesterol [GO:0070723]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; response to cholesterol [GO:0070723]				3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity [GO:0047071]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d2zi8b1_d3ecjd1__1			Actinobacteria	Actinobacteria	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity [GO:0047071]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; aromatic compound catabolic process [GO:0019439]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; response to cholesterol [GO:0070723]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; response to cholesterol [GO:0070723]				3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity [GO:0047071]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d2zica1_d2e3za___1		Fungi	Firmicutes	Basidiomycota	cytoplasm [GO:0005737]; glucan 1,6-alpha-glucosidase activity [GO:0043896]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	cytoplasm [GO:0005737]		glucan 1,6-alpha-glucosidase activity [GO:0043896]	beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; scopolin beta-glucosidase activity [GO:0102483]
d2zica1_d2v38a___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glucan 1,6-alpha-glucosidase activity [GO:0043896]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	glucan 1,6-alpha-glucosidase activity [GO:0043896]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]
d2zija__d2b72a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2zika__d4i7na1__1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2zila__d1li3a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2zila__d3rt5x___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2zirb__d1tnul___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d2zisb__d1umpc2__1	Metazoa		Chordata	Firmicutes	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d2zitc2_d1wdta1__1			Proteobacteria	Deinococcus-Thermus	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]					NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d2zitd2_d4r6ec2__1		Metazoa	Proteobacteria	Chordata	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]		apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]		membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d2zj3a__d1n8ta___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; circadian regulation of gene expression [GO:0032922]; energy reserve metabolic process [GO:0006112]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; IRE1-mediated unfolded protein response [GO:0036498]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	circadian regulation of gene expression [GO:0032922]; energy reserve metabolic process [GO:0006112]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; IRE1-mediated unfolded protein response [GO:0036498]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]
d2zjoa1_d1bmfc3__1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	ATP synthesis coupled proton transport [GO:0015986]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2zjoa2_d5cllc___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d2zjpb1_d1kqsb___1			Deinococcus-Thermus	Euryarchaeota	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2zjpe2_d2qbkg1__1			Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	
d2zjpk1_d1gd8d___1			Deinococcus-Thermus	Deinococcus-Thermus	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	ribosome [GO:0005840]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	structural constituent of ribosome [GO:0003735]
d2zjpo1_d3d5dv1__1			Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	
d2zjpq1_d1vqns1__1			Deinococcus-Thermus	Euryarchaeota	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d2zjqg1_d2qozj1__1			Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	
d2zjqk1_d2j28n1__1			Deinococcus-Thermus	Proteobacteria	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	translation [GO:0006412]	negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]
d2zjsh1_d3u79b___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d2zjub1_d4frrf1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2zjuc1_d4qabd1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2zjuc1_d5afkd___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2zjud1_d2w8gb___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2zjue1_d5afna___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2zjvc1_d3t4ma1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2zjvd1_d3sioj1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d2zjve1_d3u8ja___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d2zkhh1_d1epfc1__1		Metazoa		Chordata		glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]		aging [GO:0007568]; animal organ regeneration [GO:0031100]; axonal fasciculation [GO:0007413]; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules [GO:0016338]; cell adhesion [GO:0007155]; cellular response to inorganic substance [GO:0071241]; cellular response to molecule of bacterial origin [GO:0071219]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]		glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]		cytoskeletal protein binding [GO:0008092]; fibroblast growth factor receptor binding [GO:0005104]; heparin binding [GO:0008201]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]
d2zkhl2_d1tqcc1__1		Metazoa		Chordata		anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]		activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of potassium ion transmembrane transport [GO:1901379]; response to oxidative stress [GO:0006979]		anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d2zkib__d3nhya___1		Metazoa	Crenarchaeota	Chordata	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d2zkid__d1h66b___1		Metazoa	Crenarchaeota	Chordata	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d2zkie__d3f6se___1			Crenarchaeota	Proteobacteria	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]					FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d2zkif__d2bzsb___1		Metazoa	Crenarchaeota	Chordata	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d2zkih__d2f1ob___1		Metazoa	Crenarchaeota	Chordata	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d2zksa__d1gja.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; membrane [GO:0016020]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cytolysis [GO:0019835]; innate immune response [GO:0045087]; T cell mediated cytotoxicity [GO:0001913]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytolysis [GO:0019835]; innate immune response [GO:0045087]; T cell mediated cytotoxicity [GO:0001913]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular region [GO:0005576]; membrane [GO:0016020]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	serine-type endopeptidase activity [GO:0004252]
d2zkxc__d2z7ya___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d2zkye__d5u9md2__1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d2zl0a__d3moya___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	enoyl-CoA hydratase activity [GO:0004300]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]		ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	enoyl-CoA hydratase activity [GO:0004300]
d2zl0a__d4ryff___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d2zl0b__d3trrc___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	isomerase activity [GO:0016853]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]		ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	isomerase activity [GO:0016853]
d2zl0g__d2j5ii___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]		ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]
d2zl0k__d1xo6b2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	acetyl-CoA carboxylase complex [GO:0009317]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]
d2zl0k__d1yg6i___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2zl2i__d5g1sk___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytoplasm [GO:0005737]; serine-type endopeptidase activity [GO:0004252]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cytoplasm [GO:0005737]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d2zl2k__d1tyfg___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2zl2l__d3q0gc___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cell wall [GO:0005618]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	fatty acid beta-oxidation [GO:0006635]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cell wall [GO:0005618]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]
d2zl2m__d5e0sl___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; plasma membrane [GO:0005886]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; plasma membrane [GO:0005886]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d2zl2n__d3ktke___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]
d2zl3e__d1wdmb4__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	fatty acid beta-oxidation [GO:0006635]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d2zl3f__d4qijf___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; 1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; menaquinone biosynthetic process [GO:0009234]; protein hexamerization [GO:0034214]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	menaquinone biosynthetic process [GO:0009234]; protein hexamerization [GO:0034214]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]
d2zl3j__d2fw2b___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	nucleus [GO:0005634]; histone acetyltransferase activity [GO:0004402]; transcription corepressor activity [GO:0003714]; spermatogenesis [GO:0007283]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	nucleus [GO:0005634]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	histone acetyltransferase activity [GO:0004402]; transcription corepressor activity [GO:0003714]
d2zl3k__d5e0sb___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; plasma membrane [GO:0005886]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; plasma membrane [GO:0005886]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d2zl3l__d1wdka4__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	fatty acid beta-oxidation [GO:0006635]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d2zl4b__d2vssf___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]		ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]
d2zl4f__d5dtwd1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	fatty acid beta-oxidation [GO:0006635]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]
d2zl4g__d1tyfe___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2zl4i__d2j5ig___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]		ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	trans-feruloyl-CoA hydratase activity [GO:0050548]; vanillin synthase activity [GO:0050547]
d2zl4j__d1yg6n___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2zleb1_d2fnec2__1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; protein C-terminus binding [GO:0008022]; cell adhesion [GO:0007155]; viral process [GO:0016032]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	cell adhesion [GO:0007155]; viral process [GO:0016032]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	protein C-terminus binding [GO:0008022]
d2zleh1_d3stjb2__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]
d2zlek1_d2koha1__1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; axonal growth cone [GO:0044295]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; endomembrane system [GO:0012505]; internode region of axon [GO:0033269]; lateral loop [GO:0043219]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]; Schmidt-Lanterman incisure [GO:0043220]; spindle [GO:0005819]; identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein phosphatase binding [GO:0019903]; apical constriction [GO:0003383]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell-cell adhesion [GO:0098609]; centrosome localization [GO:0051642]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; positive regulation of receptor internalization [GO:0002092]; protein localization [GO:0008104]; protein targeting to membrane [GO:0006612]; regulation of actin filament-based process [GO:0032970]; regulation of cellular localization [GO:0060341]; wound healing, spreading of cells [GO:0044319]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	apical constriction [GO:0003383]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell division [GO:0051301]; centrosome localization [GO:0051642]; establishment of cell polarity [GO:0030010]; establishment of centrosome localization [GO:0051660]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; microtubule cytoskeleton organization [GO:0000226]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; positive regulation of receptor internalization [GO:0002092]; protein localization [GO:0008104]; protein targeting to membrane [GO:0006612]; regulation of actin filament-based process [GO:0032970]; regulation of cellular localization [GO:0060341]; wound healing, spreading of cells [GO:0044319]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical plasma membrane [GO:0016324]; axonal growth cone [GO:0044295]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; endomembrane system [GO:0012505]; internode region of axon [GO:0033269]; lateral loop [GO:0043219]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]; Schmidt-Lanterman incisure [GO:0043220]; spindle [GO:0005819]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	identical protein binding [GO:0042802]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol binding [GO:0035091]; protein phosphatase binding [GO:0019903]
d2zlta__d5nb3c___1	Metazoa		Chordata	Cyanobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2zlub__d1ew6b___1	Metazoa	Metazoa	Chordata	Annelida	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d2zlva__d4f6ia___1	Metazoa	Metazoa	Chordata	Nemertea (ribbon worms)	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2zlwc__d2h35a___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2zlxb__d1a6ma___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2zlza__d4nahd___1				Firmicutes		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]		coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d2zmkb__d4xq4a___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]
d2zmla__d4ixla1__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]
d2zmlb__d4c4da___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d2zmld__d4uw3b___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d2zmna__d3pvnn___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d2zmnc__d2zhlb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]
d2zmnd__d5e88a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d2zmya1_d2p3xa___1		Viridiplantae	Actinobacteria	Streptophyta	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	chloroplast thylakoid lumen [GO:0009543]; catechol oxidase activity [GO:0004097]; metal ion binding [GO:0046872]; pigment biosynthetic process [GO:0046148]		pigment biosynthetic process [GO:0046148]		chloroplast thylakoid lumen [GO:0009543]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	catechol oxidase activity [GO:0004097]; metal ion binding [GO:0046872]
d2znta__d2voza___1	Metazoa		Chordata	Cyanobacteria	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; thylakoid membrane [GO:0042651]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]	outer membrane-bounded periplasmic space [GO:0030288]; thylakoid membrane [GO:0042651]	glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	metal ion binding [GO:0046872]
d2znta__d5on8b___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]
d2znwa1_d3tm6h1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2znwa2_d1duzb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2znwb1_d5ljyh1__1	Metazoa		Chordata	Negarnaviricota	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi membrane [GO:0044178]; host cell surface [GO:0044228]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; signal transduction [GO:0007165]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host TRAF activity [GO:0039547]; virion attachment to host cell [GO:0019062]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; signal transduction [GO:0007165]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host TRAF activity [GO:0039547]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi membrane [GO:0044178]; host cell surface [GO:0044228]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d2znwb2_d3d6ga2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2znxz__d3a3rx___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2znyb2_d2cg4b2__1			Euryarchaeota	Proteobacteria	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	amino acid binding [GO:0016597]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; response to amino acid [GO:0043200]		negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; response to amino acid [GO:0043200]			DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	amino acid binding [GO:0016597]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]
d2znyc2_d5y02k___1		Viridiplantae	Euryarchaeota	Streptophyta	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	lyase activity [GO:0016829]					DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	lyase activity [GO:0016829]
d2znye2_d1x8dc___1			Euryarchaeota	Proteobacteria	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	cytoplasm [GO:0005737]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; rhamnose catabolic process [GO:0019301]		rhamnose catabolic process [GO:0019301]		cytoplasm [GO:0005737]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]
d2znyh2_d3qmqd1__1			Euryarchaeota	Proteobacteria	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	cytosol [GO:0005829]; (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity [GO:0002952]; intramolecular oxidoreductase activity, interconverting aldoses and ketoses [GO:0016861]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]				cytosol [GO:0005829]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity [GO:0002952]; intramolecular oxidoreductase activity, interconverting aldoses and ketoses [GO:0016861]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]
d2znzb2_d4fpim___1			Euryarchaeota	Actinobacteria	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]		beta-ketoadipate pathway [GO:0042952]			DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	muconolactone delta-isomerase activity [GO:0016159]
d2znzh2_d3vedb___1			Euryarchaeota	Actinobacteria	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]					DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d2zo9c__d4moya___1		Metazoa	Proteobacteria	Chordata	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]
d2zoaa__d2dxnb___1			Proteobacteria	Proteobacteria	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]					3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d2zoab__d5b8ia___1		Fungi	Proteobacteria	Ascomycota	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	phosphoprotein phosphatase activity [GO:0004721]					3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	phosphoprotein phosphatase activity [GO:0004721]
d2zoca__d2hyva___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phospholipase inhibitor activity [GO:0004859]; epithelial cell differentiation [GO:0030855]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]	azurophil granule lumen [GO:0035578]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell cortex [GO:0005938]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; macropinosome [GO:0044354]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; myelin sheath adaxonal region [GO:0035749]; nucleus [GO:0005634]; PCSK9-AnxA2 complex [GO:1990667]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; sarcolemma [GO:0042383]; Schmidt-Lanterman incisure [GO:0043220]; vesicle [GO:0031982]; bone sialoprotein binding [GO:0044730]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium channel activity [GO:0005262]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; molecular function regulator [GO:0098772]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipase A2 inhibitor activity [GO:0019834]; protease binding [GO:0002020]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; virion binding [GO:0046790]; voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [GO:0099511]; angiogenesis [GO:0001525]; biomineral tissue development [GO:0031214]; body fluid secretion [GO:0007589]; catabolism by host of symbiont protein [GO:0052362]; collagen fibril organization [GO:0030199]; endocardial cell differentiation [GO:0060956]; fibrinolysis [GO:0042730]; growth plate cartilage development [GO:0003417]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane raft assembly [GO:0001765]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of development of symbiont involved in interaction with host [GO:0044147]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; neutrophil degranulation [GO:0043312]; osteoclast development [GO:0036035]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of low-density lipoprotein particle receptor binding [GO:1905597]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor recycling [GO:0001921]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of vacuole organization [GO:0044090]; positive regulation of vesicle fusion [GO:0031340]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; regulation of plasminogen activation [GO:0010755]; response to thyroid hormone [GO:0097066]; vesicle budding from membrane [GO:0006900]	epithelial cell differentiation [GO:0030855]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; biomineral tissue development [GO:0031214]; body fluid secretion [GO:0007589]; catabolism by host of symbiont protein [GO:0052362]; collagen fibril organization [GO:0030199]; endocardial cell differentiation [GO:0060956]; fibrinolysis [GO:0042730]; growth plate cartilage development [GO:0003417]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane raft assembly [GO:0001765]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of development of symbiont involved in interaction with host [GO:0044147]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; neutrophil degranulation [GO:0043312]; osteoclast development [GO:0036035]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of low-density lipoprotein particle clearance [GO:1905581]; positive regulation of low-density lipoprotein particle receptor binding [GO:1905597]; positive regulation of low-density lipoprotein receptor activity [GO:1905599]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905602]; positive regulation of receptor recycling [GO:0001921]; positive regulation of vacuole organization [GO:0044090]; positive regulation of vesicle fusion [GO:0031340]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; regulation of plasminogen activation [GO:0010755]; response to thyroid hormone [GO:0097066]; vesicle budding from membrane [GO:0006900]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	azurophil granule lumen [GO:0035578]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell cortex [GO:0005938]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; macropinosome [GO:0044354]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; myelin sheath adaxonal region [GO:0035749]; nucleus [GO:0005634]; PCSK9-AnxA2 complex [GO:1990667]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; sarcolemma [GO:0042383]; Schmidt-Lanterman incisure [GO:0043220]; vesicle [GO:0031982]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phospholipase inhibitor activity [GO:0004859]	bone sialoprotein binding [GO:0044730]; cadherin binding involved in cell-cell adhesion [GO:0098641]; calcium channel activity [GO:0005262]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; molecular function regulator [GO:0098772]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; phospholipase A2 inhibitor activity [GO:0019834]; protease binding [GO:0002020]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; virion binding [GO:0046790]; voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels [GO:0099511]
d2zocb__d1w45b___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phospholipase inhibitor activity [GO:0004859]; epithelial cell differentiation [GO:0030855]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; blood coagulation [GO:0007596]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of serine-type endopeptidase activity [GO:1900004]	epithelial cell differentiation [GO:0030855]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]	blood coagulation [GO:0007596]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; negative regulation of phospholipase A2 activity [GO:1900138]; negative regulation of serine-type endopeptidase activity [GO:1900004]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; late endosome membrane [GO:0031902]; plasma membrane [GO:0005886]	calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phospholipase inhibitor activity [GO:0004859]	actin filament binding [GO:0051015]; calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]
d2zoda2_d3u0oa2__1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]; selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]; selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]
d2zoha__d4eesa___1		Viridiplantae	Proteobacteria	Streptophyta	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cell [GO:0005623]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plastid [GO:0009536]; ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein serine/threonine kinase activity [GO:0004674]; chloroplast relocation [GO:0009902]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-chromophore linkage [GO:0018298]; response to blue light [GO:0009637]; stomatal movement [GO:0010118]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	chloroplast relocation [GO:0009902]; circadian rhythm [GO:0007623]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; protein phosphorylation [GO:0006468]; response to blue light [GO:0009637]; stomatal movement [GO:0010118]		cell [GO:0005623]; cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plastid [GO:0009536]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; blue light photoreceptor activity [GO:0009882]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein serine/threonine kinase activity [GO:0004674]
d2zoia__d1xj3a___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]		integral component of plasma membrane [GO:0005887]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d2zokc2_d4ah2a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d2zokf__d2pw1b1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2zokh__d1g84a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2zolb__d2qhle___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2zold__d1cfsa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d2zold__d1ed3a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2zona2_d1ilsd___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2zonb1_d1niba1__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2zonb1_d4hz1d___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d2zonb2_d3pcya___1		Viridiplantae	Proteobacteria	Streptophyta	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	nitrogen compound metabolic process [GO:0006807]			chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d2zonc1_d1wa1x2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d2zowb__d2gbua___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d2zoyb2_d2o7oa2__1			Actinobacteria	Proteobacteria	DNA binding [GO:0003677]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]			DNA binding [GO:0003677]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d2zpca1_d2w7qa___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; chaperone-mediated protein transport across periplasmic space [GO:0072323]; lipoprotein localization to outer membrane [GO:0044874]; lipoprotein transport [GO:0042953]	outer membrane-bounded periplasmic space [GO:0030288]; chaperone-mediated protein transport across periplasmic space [GO:0072323]; lipoprotein localization to outer membrane [GO:0044874]; lipoprotein transport [GO:0042953]	chaperone-mediated protein transport across periplasmic space [GO:0072323]; lipoprotein localization to outer membrane [GO:0044874]; lipoprotein transport [GO:0042953]	chaperone-mediated protein transport across periplasmic space [GO:0072323]; lipoprotein localization to outer membrane [GO:0044874]; lipoprotein transport [GO:0042953]	outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]		
d2zpda1_d3mh8a___1			Proteobacteria	Actinobacteria	outer membrane-bounded periplasmic space [GO:0030288]; chaperone-mediated protein transport across periplasmic space [GO:0072323]; lipoprotein localization to outer membrane [GO:0044874]; lipoprotein transport [GO:0042953]	bacterial extracellular vesicle [GO:0097691]; cell surface [GO:0009986]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; glycolipid binding [GO:0051861]; phosphatidylinositol binding [GO:0035091]; lipid transport [GO:0006869]; pathogenesis [GO:0009405]; response to antibiotic [GO:0046677]	chaperone-mediated protein transport across periplasmic space [GO:0072323]; lipoprotein localization to outer membrane [GO:0044874]; lipoprotein transport [GO:0042953]	lipid transport [GO:0006869]; pathogenesis [GO:0009405]; response to antibiotic [GO:0046677]	outer membrane-bounded periplasmic space [GO:0030288]	bacterial extracellular vesicle [GO:0097691]; cell surface [GO:0009986]; cell wall [GO:0005618]; plasma membrane [GO:0005886]		glycolipid binding [GO:0051861]; phosphatidylinositol binding [GO:0035091]
d2zpeb__d3qz5f___1			Actinobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	
d2zpgb__d4fm4f___1			Actinobacteria	Proteobacteria	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d2zphb__d4zgej___1			Actinobacteria	Proteobacteria	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d2zpib__d4zgjp___1			Actinobacteria	Proteobacteria	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d2zpna__d3m3jc___1	Fungi	Metazoa	Ascomycota	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; Cvt vesicle membrane [GO:0033110]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; fungal-type vacuole membrane [GO:0000329]; phagophore assembly site [GO:0000407]; vacuole-isolation membrane contact site [GO:0120095]; phosphatidylethanolamine binding [GO:0008429]; protein tag [GO:0031386]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular protein-containing complex localization [GO:0034629]; cellular response to nitrogen starvation [GO:0006995]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; membrane fusion [GO:0061025]; piecemeal microautophagy of the nucleus [GO:0034727]; protein localization to phagophore assembly site [GO:0034497]; protein targeting to vacuole involved in autophagy [GO:0071211]; regulation of macroautophagy [GO:0016241]; reticulophagy [GO:0061709]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular protein-containing complex localization [GO:0034629]; cellular response to nitrogen starvation [GO:0006995]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; membrane fusion [GO:0061025]; piecemeal microautophagy of the nucleus [GO:0034727]; protein localization to phagophore assembly site [GO:0034497]; protein targeting to vacuole involved in autophagy [GO:0071211]; regulation of macroautophagy [GO:0016241]; reticulophagy [GO:0061709]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; Cvt vesicle membrane [GO:0033110]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; fungal-type vacuole membrane [GO:0000329]; phagophore assembly site [GO:0000407]; vacuole-isolation membrane contact site [GO:0120095]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	phosphatidylethanolamine binding [GO:0008429]; protein tag [GO:0031386]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2zpnb__d3sdlc2__1	Fungi	Metazoa	Ascomycota	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; Cvt vesicle membrane [GO:0033110]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; fungal-type vacuole membrane [GO:0000329]; phagophore assembly site [GO:0000407]; vacuole-isolation membrane contact site [GO:0120095]; phosphatidylethanolamine binding [GO:0008429]; protein tag [GO:0031386]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular protein-containing complex localization [GO:0034629]; cellular response to nitrogen starvation [GO:0006995]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; membrane fusion [GO:0061025]; piecemeal microautophagy of the nucleus [GO:0034727]; protein localization to phagophore assembly site [GO:0034497]; protein targeting to vacuole involved in autophagy [GO:0071211]; regulation of macroautophagy [GO:0016241]; reticulophagy [GO:0061709]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular protein-containing complex localization [GO:0034629]; cellular response to nitrogen starvation [GO:0006995]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; membrane fusion [GO:0061025]; piecemeal microautophagy of the nucleus [GO:0034727]; protein localization to phagophore assembly site [GO:0034497]; protein targeting to vacuole involved in autophagy [GO:0071211]; regulation of macroautophagy [GO:0016241]; reticulophagy [GO:0061709]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; Cvt vesicle membrane [GO:0033110]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; fungal-type vacuole membrane [GO:0000329]; phagophore assembly site [GO:0000407]; vacuole-isolation membrane contact site [GO:0120095]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	phosphatidylethanolamine binding [GO:0008429]; protein tag [GO:0031386]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2zpqa__d1p10a___1	Metazoa		Chordata	Proteobacteria	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]				extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d2zq1a__d1ns3.1__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d2zq1a__d2f9nd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2zq4a__d1iy4a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2zqja__d4c9pa___1			Firmicutes	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]				integral component of membrane [GO:0016021]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2zqjb__d1jfba___1		Fungi	Firmicutes	Ascomycota	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2zqjb__d4ejgc___1		Metazoa	Firmicutes	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d2zqkb2_d1kzb1___1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]
d2zqkb2_d1ypoa___1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d2zqna__d4zfwb2__1	Metazoa	Viridiplantae	Annelida	Streptophyta	carbohydrate binding [GO:0030246]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2zqnb__d2d23a2__1	Metazoa		Annelida	Actinobacteria	carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]	endo-1,4-beta-xylanase activity [GO:0031176]
d2zqoa1_d4zfyb2__1	Metazoa	Viridiplantae	Annelida	Streptophyta	carbohydrate binding [GO:0030246]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2zqob__d1ybia2__1	Metazoa		Annelida	Firmicutes	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d2zqqa__d3mt6j___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d2zqqe__d3iavb1__1	Metazoa		Chordata	Actinobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	fatty acid biosynthetic process [GO:0006633]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	acetyl-CoA carboxylase complex [GO:0009317]	enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]
d2zqra__d3ktga1__1	Metazoa		Chordata	Firmicutes	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]
d2zqre__d4fzwa___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	enoyl-CoA hydratase activity [GO:0004300]; identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]; phenylacetate catabolic process [GO:0010124]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	fatty acid beta-oxidation [GO:0006635]; phenylacetate catabolic process [GO:0010124]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]	enoyl-CoA hydratase activity [GO:0004300]; identical protein binding [GO:0042802]; isomerase activity [GO:0016853]
d2zqua2_d1fkib___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]
d2zqxa__d4ejhf___1		Metazoa	Firmicutes	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d2zqxc__d1ehfa___1		Fungi	Firmicutes	Ascomycota	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2zqxc__d2p85e___1		Metazoa	Firmicutes	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d2zqya2_d3vphb2__1			Firmicutes	Deinococcus-Thermus	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d2zqyb1_d5lc1e1__1			Firmicutes		cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]
d2zqyb1_d5nqqb1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d2zqyc2_d1smke2__1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	glyoxysome [GO:0009514]	L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]
d2zqyd2_d3gvia2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]
d2zqze1_d4wkgb3__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	glycolytic process [GO:0006096]	lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; protein hexamerization [GO:0034214]; response to antibiotic [GO:0046677]; UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process [GO:2001315]; UDP-D-xylose biosynthetic process [GO:0033320]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity [GO:0099619]; UDP-glucuronate decarboxylase activity [GO:0048040]; UDP-glucuronic acid dehydrogenase activity [GO:0099618]
d2zqze1_d5nqqa1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d2zqzf1_d1mldb1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; chaperone binding [GO:0051087]; L-malate dehydrogenase activity [GO:0030060]; protein homodimerization activity [GO:0042803]; aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	L-lactate dehydrogenase activity [GO:0004459]	chaperone binding [GO:0051087]; L-malate dehydrogenase activity [GO:0030060]; protein homodimerization activity [GO:0042803]
d2zqzf1_d5es3a1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d2zqzf2_d3pqfa2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d2zr1b1_d2mllb2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process in other organism [GO:0044533]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process in other organism [GO:0044533]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d2zr1d1_d1xyfb1__1	Viridiplantae		Streptophyta	Actinobacteria	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process in other organism [GO:0044533]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	defense response [GO:0006952]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process in other organism [GO:0044533]	polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	endo-1,4-beta-xylanase activity [GO:0031176]
d2zr1d1_d5gqdb2__1	Viridiplantae		Streptophyta	Actinobacteria	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process in other organism [GO:0044533]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	defense response [GO:0006952]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process in other organism [GO:0044533]	polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	endo-1,4-beta-xylanase activity [GO:0031176]
d2zr4a2_d2pbca1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d2zr5a2_d2fapa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]
d2zrda2_d4ppna2__1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA-dependent ATPase activity [GO:0008094]; single-stranded DNA binding [GO:0003697]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	cytosol [GO:0005829]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; damaged DNA binding [GO:0003684]; DNA-dependent ATPase activity [GO:0008094]; endodeoxyribonuclease activity [GO:0004520]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; recombinase activity [GO:0000150]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; recombinational repair [GO:0000725]; response to antibiotic [GO:0046677]; SOS response [GO:0009432]; strand invasion [GO:0042148]; UV protection [GO:0009650]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	cellular response to DNA damage stimulus [GO:0006974]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; recombinational repair [GO:0000725]; response to antibiotic [GO:0046677]; SOS response [GO:0009432]; strand invasion [GO:0042148]; UV protection [GO:0009650]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA-dependent ATPase activity [GO:0008094]; single-stranded DNA binding [GO:0003697]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA-dependent ATPase activity [GO:0008094]; endodeoxyribonuclease activity [GO:0004520]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; recombinase activity [GO:0000150]; single-stranded DNA binding [GO:0003697]
d2zrsa__d3ucya___1	Metazoa	Metazoa	Chordata	Chordata	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d2zrse__d2l5xc___1	Metazoa	Metazoa	Chordata	Chordata	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	cytokine secretion [GO:0050663]; interleukin-1 alpha secretion [GO:0050703]; mast cell degranulation [GO:0043303]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cell shape [GO:0008360]; response to copper ion [GO:0046688]; response to electrical stimulus [GO:0051602]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; fibroblast growth factor binding [GO:0017134]; lipid binding [GO:0008289]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d2zrsg__d1ozob___1	Metazoa	Metazoa	Chordata	Chordata	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; microvillus membrane [GO:0031528]; nuclear body [GO:0016604]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; transition metal ion binding [GO:0046914]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; response to organic substance [GO:0010033]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; response to organic substance [GO:0010033]	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; microvillus membrane [GO:0031528]; nuclear body [GO:0016604]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]	cadherin binding [GO:0045296]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; transition metal ion binding [GO:0046914]
d2zrsh__d1s5gz___1	Metazoa	Metazoa	Chordata	Mollusca	COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein monoubiquitination [GO:1902527]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]		COPII vesicle coat [GO:0030127]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum exit site [GO:0070971]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; molecular adaptor activity [GO:0060090]; protein binding, bridging [GO:0030674]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]
d2zs0a__d3pi2a___1	Metazoa	Metazoa	Annelida	Mollusca	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2zs0b__d1x3ka___1	Metazoa	Metazoa	Annelida	Arthropoda	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2zs0c__d1bvda___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2zs7a__d1h8hd3__1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	coenzyme A biosynthetic process [GO:0015937]	ATP synthesis coupled proton transport [GO:0015986]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d2zsda__d1yraa2__1			Actinobacteria	Euryarchaeota	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]
d2zsea__d3m0ef___1			Actinobacteria	Aquificae	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	coenzyme A biosynthetic process [GO:0015937]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d2zsjb__d1pwee___1		Metazoa	Aquificae	Chordata	cytoplasm [GO:0005737]; pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]; threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]; gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]	threonine biosynthetic process [GO:0009088]	gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]	L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]
d2zskb1_d2dx7b2__1			Euryarchaeota	Euryarchaeota	amino-acid racemase activity [GO:0047661]; nitrogen compound metabolic process [GO:0006807]	aspartate racemase activity [GO:0047689]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			amino-acid racemase activity [GO:0047661]	aspartate racemase activity [GO:0047689]
d2zskb1_d5hraa2__1			Euryarchaeota	Proteobacteria	amino-acid racemase activity [GO:0047661]; nitrogen compound metabolic process [GO:0006807]	aspartate racemase activity [GO:0047689]; glutamate racemase activity [GO:0008881]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			amino-acid racemase activity [GO:0047661]	aspartate racemase activity [GO:0047689]; glutamate racemase activity [GO:0008881]
d2zskb2_d5hrcb2__1			Euryarchaeota	Proteobacteria	amino-acid racemase activity [GO:0047661]; nitrogen compound metabolic process [GO:0006807]	aspartate racemase activity [GO:0047689]; glutamate racemase activity [GO:0008881]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			amino-acid racemase activity [GO:0047661]	aspartate racemase activity [GO:0047689]; glutamate racemase activity [GO:0008881]
d2zsna__d2vyya___1	Metazoa	Metazoa	Chordata	Nemertea (ribbon worms)	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2zsoa__d3wctb___1	Metazoa	Metazoa	Chordata	Annelida	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2zsub__d2cmhc___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; spermidine synthase activity [GO:0004766]; spermidine biosynthetic process [GO:0008295]	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	spermidine biosynthetic process [GO:0008295]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	spermidine synthase activity [GO:0004766]	spermidine synthase activity [GO:0004766]
d2zsue__d2o05a1__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; spermidine synthase activity [GO:0004766]; spermidine biosynthetic process [GO:0008295]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; spermidine synthase activity [GO:0004766]; cellular response to leukemia inhibitory factor [GO:1990830]; polyamine biosynthetic process [GO:0006596]; polyamine metabolic process [GO:0006595]; spermidine biosynthetic process [GO:0008295]	spermidine biosynthetic process [GO:0008295]	cellular response to leukemia inhibitory factor [GO:1990830]; polyamine biosynthetic process [GO:0006596]; polyamine metabolic process [GO:0006595]; spermidine biosynthetic process [GO:0008295]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	spermidine synthase activity [GO:0004766]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; spermidine synthase activity [GO:0004766]
d2zsvb__d4h0ia2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d2zsvd__d4lhua2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d2zswb__d1q8mc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]; acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	acute inflammatory response [GO:0002526]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	scaffold protein binding [GO:0097110]; signaling receptor activity [GO:0038023]
d2zswd__d2p8pb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d2zsya__d3nmmb___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d2zt4a__d3v58a___1	Metazoa		Chordata	Rhodophyta	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d2ztia__d1u5wb2__1			Euryarchaeota	Proteobacteria	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleotide binding [GO:0000166]; nucleotide metabolic process [GO:0009117]; response to antibiotic [GO:0046677]; thiamine metabolic process [GO:0006772]	nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleotide metabolic process [GO:0009117]; response to antibiotic [GO:0046677]; thiamine metabolic process [GO:0006772]			metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleotide binding [GO:0000166]
d2ztia__d2mjpa___1			Euryarchaeota	Euryarchaeota	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	dITP diphosphatase activity [GO:0035870]; ITP diphosphatase activity [GO:0036220]; metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; XTP diphosphatase activity [GO:0036222]; nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]			metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]	dITP diphosphatase activity [GO:0035870]; ITP diphosphatase activity [GO:0036220]; metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; XTP diphosphatase activity [GO:0036222]
d2ztla__d3byza___1		Metazoa	Proteobacteria	Chordata	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d2ztlb__d1nr7c1__1		Metazoa	Proteobacteria	Chordata	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d2ztma__d2bd0a1__1			Proteobacteria	Chlorobi	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]				cytoplasm [GO:0005737]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d2ztva__d4nbra1__1			Proteobacteria	Proteobacteria	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	oxidoreductase activity [GO:0016491]					3-hydroxybutyrate dehydrogenase activity [GO:0003858]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	oxidoreductase activity [GO:0016491]
d2ztza__d1l1na___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host gene expression [GO:0039656]; modulation by virus of host NIK/NF-kappaB signaling [GO:0061765]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive regulation by virus of host cytokine production [GO:0044832]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host gene expression [GO:0039656]; modulation by virus of host NIK/NF-kappaB signaling [GO:0061765]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive regulation by virus of host cytokine production [GO:0044832]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d2ztza__d3a8da___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host gene expression [GO:0039656]; modulation by virus of host NIK/NF-kappaB signaling [GO:0061765]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive regulation by virus of host cytokine production [GO:0044832]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host gene expression [GO:0039656]; modulation by virus of host NIK/NF-kappaB signaling [GO:0061765]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive regulation by virus of host cytokine production [GO:0044832]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d2zu2b__d1lvoe___1					host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d2zuac__d3fcwb1__1			Euryarchaeota		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2zuad__d1nhkl___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d2zuha__d3czha1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; vitamin D3 25-hydroxylase activity [GO:0030343]; calcitriol biosynthetic process from calciol [GO:0036378]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; response to cesium ion [GO:0010164]; response to ionizing radiation [GO:0010212]; vitamin D metabolic process [GO:0042359]; vitamin metabolic process [GO:0006766]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	calcitriol biosynthetic process from calciol [GO:0036378]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; response to cesium ion [GO:0010164]; response to ionizing radiation [GO:0010212]; vitamin D metabolic process [GO:0042359]; vitamin metabolic process [GO:0006766]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; vitamin D3 25-hydroxylase activity [GO:0030343]
d2zuja__d2whwb___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d2zv3d__d1xtya___1			Euryarchaeota	Crenarchaeota	cytosol [GO:0005829]; mitochondrion [GO:0005739]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	aminoacyl-tRNA hydrolase activity [GO:0004045]	aminoacyl-tRNA hydrolase activity [GO:0004045]
d2zvna1_d1wgda1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; Lewy body core [GO:1990037]; membrane [GO:0016020]; ion channel binding [GO:0044325]; protein binding, bridging involved in substrate recognition for ubiquitination [GO:1990756]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; endoplasmic reticulum unfolded protein response [GO:0030968]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903069]; regulation of protein ubiquitination [GO:0031396]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	endoplasmic reticulum calcium ion homeostasis [GO:0032469]; endoplasmic reticulum unfolded protein response [GO:0030968]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903069]; regulation of protein ubiquitination [GO:0031396]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; Lewy body core [GO:1990037]; membrane [GO:0016020]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	ion channel binding [GO:0044325]; protein binding, bridging involved in substrate recognition for ubiquitination [GO:1990756]
d2zvna2_d2d10a3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d2zvnc1_d1r4nj___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	anatomical structure morphogenesis [GO:0009653]; cellular iron ion homeostasis [GO:0006879]; cellular protein modification process [GO:0006464]; modification-dependent protein catabolic process [GO:0019941]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein localization [GO:0008104]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of proteolysis [GO:0030162]; regulation of transcription by RNA polymerase II [GO:0006357]; response to organic cyclic compound [GO:0014070]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d2zvne2_d3qq8b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d2zvqx__d2iyta___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; aryl sulfotransferase activity [GO:0004062]; sulfotransferase activity [GO:0008146]; catecholamine metabolic process [GO:0006584]; lipid metabolic process [GO:0006629]; sulfate assimilation [GO:0000103]; sulfation [GO:0051923]	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	catecholamine metabolic process [GO:0006584]; lipid metabolic process [GO:0006629]; sulfate assimilation [GO:0000103]; sulfation [GO:0051923]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	aryl sulfotransferase activity [GO:0004062]; sulfotransferase activity [GO:0008146]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]
d2zwba__d1di3a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d2zwba__d3ht9a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d2zwga1_d4hd6a___1			Actinobacteria	Firmicutes	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d2zwka1_d1cwva4__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell surface [GO:0009986]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]		
d2zwkc2_d3bbsa___1			Proteobacteria		cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]			
d2zwma__d1xhea1__1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d2zwta__d1dz6a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	(+)-camphor catabolic process [GO:0019383]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d2zwya2_d6taaa1__1		Fungi	Thermotogae	Ascomycota	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate catabolic process [GO:0016052]	lysosome [GO:0005764]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]	alpha-L-fucosidase activity [GO:0004560]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d2zwza2_d3vx0a2__1		Fungi	Thermotogae	Ascomycota	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate catabolic process [GO:0016052]	lysosome [GO:0005764]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]	alpha-L-fucosidase activity [GO:0004560]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d2zx5b2_d3lxca2__1		Metazoa	Thermotogae	Chordata	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	lysosome [GO:0005764]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	alpha-L-fucosidase activity [GO:0004560]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d2zx6a1_d3e1f13__1			Thermotogae	Proteobacteria	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	lactose catabolic process [GO:0005990]	lysosome [GO:0005764]	beta-galactosidase complex [GO:0009341]	alpha-L-fucosidase activity [GO:0004560]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2zx6a2_d1peza3__1			Thermotogae	Firmicutes	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-L-fucosidase activity [GO:0004560]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2zx6a2_d1xh0a1__1		Metazoa	Thermotogae	Chordata	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	lysosome [GO:0005764]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-L-fucosidase activity [GO:0004560]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d2zx6b1_d3gxmc2__1		Metazoa	Thermotogae	Chordata	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	lysosome [GO:0005764]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	alpha-L-fucosidase activity [GO:0004560]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d2zx6b2_d1j0ia2__1			Thermotogae	Firmicutes	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	lysosome [GO:0005764]		alpha-L-fucosidase activity [GO:0004560]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d2zx6b2_d3o7zd3__1			Thermotogae		lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]		fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]		lysosome [GO:0005764]		alpha-L-fucosidase activity [GO:0004560]	
d2zx7a1_d2vr4b5__1			Thermotogae	Bacteroidetes	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lysosome [GO:0005764]		alpha-L-fucosidase activity [GO:0004560]	beta-mannosidase activity [GO:0004567]
d2zx7a2_d1bvnp1__1		Metazoa	Thermotogae	Chordata	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate catabolic process [GO:0016052]	lysosome [GO:0005764]	extracellular space [GO:0005615]	alpha-L-fucosidase activity [GO:0004560]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d2zx8a2_d1v3lb3__1			Thermotogae	Firmicutes	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-L-fucosidase activity [GO:0004560]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2zx8b1_d1px3c5__1			Thermotogae	Proteobacteria	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	lactose catabolic process [GO:0005990]	lysosome [GO:0005764]	beta-galactosidase complex [GO:0009341]	alpha-L-fucosidase activity [GO:0004560]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2zxab2_d1i75a3__1			Thermotogae	Firmicutes	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-L-fucosidase activity [GO:0004560]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d2zxba1_d3t08a3__1			Thermotogae	Proteobacteria	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	lactose catabolic process [GO:0005990]	lysosome [GO:0005764]	beta-galactosidase complex [GO:0009341]	alpha-L-fucosidase activity [GO:0004560]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d2zxbb2_d1e3za1__1			Thermotogae	Firmicutes	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-L-fucosidase activity [GO:0004560]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d2zxda2_d1m53a1__1			Thermotogae	Proteobacteria	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	catalytic activity [GO:0003824]; carbohydrate metabolic process [GO:0005975]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	lysosome [GO:0005764]		alpha-L-fucosidase activity [GO:0004560]	catalytic activity [GO:0003824]
d2zxdb2_d2pwfd2__1			Thermotogae	Proteobacteria	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	lysosome [GO:0005764]		alpha-L-fucosidase activity [GO:0004560]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d2zxdb2_d4nxsb2__1		Metazoa	Thermotogae	Chordata	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	lysosome [GO:0005764]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	alpha-L-fucosidase activity [GO:0004560]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d2zxwb2_d1qnid1__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	membrane [GO:0016020]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	membrane [GO:0016020]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d2zxwo2_d4fa7b2__1	Metazoa		Chordata	Deinococcus-Thermus	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d2zxya__d5tisv___1			Aquificae	Cyanobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	integral component of membrane [GO:0016021]; photosystem II [GO:0009523]; thylakoid membrane [GO:0042651]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]		integral component of membrane [GO:0016021]; photosystem II [GO:0009523]; thylakoid membrane [GO:0042651]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	
d2zyaa1_d1i2ba1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; identical protein binding [GO:0042802]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; protein homodimerization activity [GO:0042803]; D-gluconate catabolic process [GO:0046177]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	chloroplast [GO:0009507]; plasma membrane [GO:0005886]; coenzyme binding [GO:0050662]; sulfotransferase activity [GO:0008146]; UDPsulfoquinovose synthase activity [GO:0046507]; zinc ion binding [GO:0008270]; cellular response to phosphate starvation [GO:0016036]; glycolipid biosynthetic process [GO:0009247]	D-gluconate catabolic process [GO:0046177]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	cellular response to phosphate starvation [GO:0016036]; glycolipid biosynthetic process [GO:0009247]	cytosol [GO:0005829]	chloroplast [GO:0009507]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; protein homodimerization activity [GO:0042803]	coenzyme binding [GO:0050662]; sulfotransferase activity [GO:0008146]; UDPsulfoquinovose synthase activity [GO:0046507]; zinc ion binding [GO:0008270]
d2zyab2_d2b0ja1__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; identical protein binding [GO:0042802]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; protein homodimerization activity [GO:0042803]; D-gluconate catabolic process [GO:0046177]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	N5,N10-methenyltetrahydromethanopterin hydrogenase activity [GO:0047068]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	D-gluconate catabolic process [GO:0046177]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; protein homodimerization activity [GO:0042803]	N5,N10-methenyltetrahydromethanopterin hydrogenase activity [GO:0047068]
d2zydb1_d2gasb___1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; identical protein binding [GO:0042802]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; protein homodimerization activity [GO:0042803]; D-gluconate catabolic process [GO:0046177]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	2'-hydroxyisoflavone reductase activity [GO:0047526]; defense response [GO:0006952]	D-gluconate catabolic process [GO:0046177]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	defense response [GO:0006952]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; protein homodimerization activity [GO:0042803]	2'-hydroxyisoflavone reductase activity [GO:0047526]
d2zyeb__d5p3na___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d2zyka__d4pfta1__1			Firmicutes	Thermotogae	plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; metal ion binding [GO:0046872]; peptide transmembrane transporter activity [GO:1904680]			plasma membrane [GO:0005886]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]	metal ion binding [GO:0046872]; peptide transmembrane transporter activity [GO:1904680]
d2zykb__d2y7ia___1			Firmicutes	Proteobacteria	plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]; metal ion binding [GO:0046872]			plasma membrane [GO:0005886]	membrane [GO:0016020]	carbohydrate transmembrane transporter activity [GO:0015144]	ligand-gated ion channel activity [GO:0015276]; metal ion binding [GO:0046872]
d2zykb__d3ua8a___1		Metazoa	Firmicutes	Chordata	plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	plasma membrane [GO:0005886]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]	carbohydrate transmembrane transporter activity [GO:0015144]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2zykd__d1sdx.1__1		Metazoa	Firmicutes	Chordata	plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]		antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]	carbohydrate transmembrane transporter activity [GO:0015144]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d2zyoa__d3r7xa___1		Metazoa	Firmicutes	Chordata	plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	plasma membrane [GO:0005886]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]	carbohydrate transmembrane transporter activity [GO:0015144]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d2zyqb2_d5trxb1__1			Actinobacteria	Actinobacteria	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity [GO:0047071]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; aromatic compound catabolic process [GO:0019439]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; response to cholesterol [GO:0070723]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; response to cholesterol [GO:0070723]				3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity [GO:0047071]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d2zywx__d1xv1b___1	Metazoa		Chordata		cytoplasm [GO:0005737]; aryl sulfotransferase activity [GO:0004062]; sulfotransferase activity [GO:0008146]; catecholamine metabolic process [GO:0006584]; lipid metabolic process [GO:0006629]; sulfate assimilation [GO:0000103]; sulfation [GO:0051923]		catecholamine metabolic process [GO:0006584]; lipid metabolic process [GO:0006629]; sulfate assimilation [GO:0000103]; sulfation [GO:0051923]		cytoplasm [GO:0005737]		aryl sulfotransferase activity [GO:0004062]; sulfotransferase activity [GO:0008146]	
d2zz1b__d3sj3b___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2zz1b__d5k2zd___1		Viridiplantae	Euryarchaeota	Streptophyta	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]; amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]		cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d2zz2a__d3nyza___1			Euryarchaeota	Crenarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	tryptophan biosynthetic process [GO:0000162]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]
d2zz2b__d3gdta___1		Fungi	Euryarchaeota	Ascomycota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]		cytosol [GO:0005829]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2zz3a__d3g1aa___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2zz3b__d1jcmp___1			Euryarchaeota	Proteobacteria	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	tryptophan biosynthetic process [GO:0000162]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]
d2zz3b__d3bpwa1__1			Euryarchaeota	Apicomplexa	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2zz4a__d1dqwa___1		Fungi	Euryarchaeota	Ascomycota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]		cytosol [GO:0005829]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2zz4b__d2czfa___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2zz5b__d3n3ma1__1			Euryarchaeota	Apicomplexa	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d2zzaa__d1dr3a___1		Metazoa	Proteobacteria	Chordata	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d2zzab__d1dhja___1			Proteobacteria	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d2zzwa__d1xc1a___1			Deinococcus-Thermus	Proteobacteria	periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; lactate transport [GO:0015727]; transmembrane transport [GO:0055085]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	lactate transport [GO:0015727]; transmembrane transport [GO:0055085]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]	periplasmic space [GO:0042597]	calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d2zzxa__d3zkla___1			Deinococcus-Thermus		periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; lactate transport [GO:0015727]; transmembrane transport [GO:0055085]		lactate transport [GO:0015727]; transmembrane transport [GO:0055085]		periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]		calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	
d2zzxb__d4o4ba1__1			Deinococcus-Thermus		periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; lactate transport [GO:0015727]; transmembrane transport [GO:0055085]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; inositol phosphate biosynthetic process [GO:0032958]	lactate transport [GO:0015727]; transmembrane transport [GO:0055085]	inositol phosphate biosynthetic process [GO:0032958]	periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]		calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; kinase activity [GO:0016301]
d2zzxb__d5cmka___1		Metazoa	Deinococcus-Thermus	Chordata	periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; lactate transport [GO:0015727]; transmembrane transport [GO:0055085]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	lactate transport [GO:0015727]; transmembrane transport [GO:0055085]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d2zzza__d3raps___1		Metazoa		Chordata		cytosol [GO:0005829]; midbody [GO:0030496]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; actin cytoskeleton reorganization [GO:0031532]; cellular protein localization [GO:0034613]; cellular response to drug [GO:0035690]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to plasma membrane [GO:0072659]; Rap protein signal transduction [GO:0032486]; regulation of dendrite morphogenesis [GO:0048814]; regulation of JNK cascade [GO:0046328]		actin cytoskeleton reorganization [GO:0031532]; cellular protein localization [GO:0034613]; cellular response to drug [GO:0035690]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to plasma membrane [GO:0072659]; Rap protein signal transduction [GO:0032486]; regulation of dendrite morphogenesis [GO:0048814]; regulation of JNK cascade [GO:0046328]		cytosol [GO:0005829]; midbody [GO:0030496]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]		GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d31bia__d1tp0a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d32c2b2_d1eapa2__1												
d35c8h1_d1bz7a2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d35c8h2_d1leka1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d35c8l2_d1eeqb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]
d3a04a__d2ag6a1__1			Crenarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	tryptophanyl-tRNA aminoacylation [GO:0006436]	tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]
d3a05a__d1s4mb2__1			Crenarchaeota	Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]; FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	tryptophanyl-tRNA aminoacylation [GO:0006436]	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]
d3a05a__d5o0db___1			Crenarchaeota	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	tryptophanyl-tRNA aminoacylation [GO:0006436]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d3a0cb__d1dlpa1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d3a0cc__d2d04d___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d3a0da__d5t20l___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d3a0ea__d3dzwa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d3a0ea__d5t20c___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d3a0gb__d3fs4d___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3a0hv__d1m70a2__1			Cyanobacteria	Proteobacteria	integral component of membrane [GO:0016021]; photosystem II reaction center [GO:0009539]; thylakoid membrane [GO:0042651]; photosynthesis [GO:0015979]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	photosynthesis [GO:0015979]		integral component of membrane [GO:0016021]; photosystem II reaction center [GO:0009539]; thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3a0hv__d2gc4d___1			Cyanobacteria	Proteobacteria	integral component of membrane [GO:0016021]; photosystem II reaction center [GO:0009539]; thylakoid membrane [GO:0042651]; photosynthesis [GO:0015979]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	photosynthesis [GO:0015979]		integral component of membrane [GO:0016021]; photosystem II reaction center [GO:0009539]; thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3a0ix1_d2gwja2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3a0ua__d2ayza1__1			Thermotogae	Proteobacteria	metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; cellular response to osmotic stress [GO:0071470]; phosphorelay signal transduction system [GO:0000160]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]; single-species biofilm formation [GO:0044010]	phosphorelay signal transduction system [GO:0000160]	cellular response to osmotic stress [GO:0071470]; phosphorelay signal transduction system [GO:0000160]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]; single-species biofilm formation [GO:0044010]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]
d3a12c1_d1rcxl2__1		Viridiplantae	Euryarchaeota	Streptophyta	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3a12d1_d2d69a2__1			Euryarchaeota	Euryarchaeota	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]			magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3a12d1_d3zxwc1__1			Euryarchaeota	Cyanobacteria	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]		AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]				magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	
d3a12g1_d1aa1e2__1		Viridiplantae	Euryarchaeota	Streptophyta	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3a12i1_d5hata1__1			Euryarchaeota	Proteobacteria	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	reductive pentose-phosphate cycle [GO:0019253]			magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3a12j1_d1bxna2__1			Euryarchaeota	Proteobacteria	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	reductive pentose-phosphate cycle [GO:0019253]			magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3a13b1_d5hjxa1__1			Euryarchaeota	Proteobacteria	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	reductive pentose-phosphate cycle [GO:0019253]			magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3a13f1_d1ir1b2__1		Viridiplantae	Euryarchaeota	Streptophyta	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3a1na__d4oknh1__1		Metazoa	Euryarchaeota	Chordata	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d3a1nb__d4wasb2__1		Fungi	Euryarchaeota	Ascomycota	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		mitochondrion [GO:0005739]	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]
d3a1qa__d1t0ya___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	BRCA1-A complex [GO:0070531]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone binding [GO:0042393]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; retinoid X receptor binding [GO:0046965]; double-strand break repair [GO:0006302]; histone H2A K63-linked deubiquitination [GO:0070537]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA repair [GO:0045739]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	cytoplasm [GO:0005737]; microtubule [GO:0005874]	double-strand break repair [GO:0006302]; histone H2A K63-linked deubiquitination [GO:0070537]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA repair [GO:0045739]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]		BRCA1-A complex [GO:0070531]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; microtubule [GO:0005874]	histone binding [GO:0042393]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; retinoid X receptor binding [GO:0046965]	
d3a20b__d1t9ma___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	FMN binding [GO:0010181]; pyridoxamine-phosphate oxidase activity [GO:0004733]; phenazine biosynthetic process [GO:0002047]; pyridoxine biosynthetic process [GO:0008615]	oxidation-reduction process [GO:0055114]	phenazine biosynthetic process [GO:0002047]; pyridoxine biosynthetic process [GO:0008615]	cytoplasm [GO:0005737]		cofactor binding [GO:0048037]	FMN binding [GO:0010181]; pyridoxamine-phosphate oxidase activity [GO:0004733]
d3a20b__d4l82c___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	FMN binding [GO:0010181]	oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]		cofactor binding [GO:0048037]	FMN binding [GO:0010181]
d3a28f__d5bsfh1__1		Viridiplantae	Actinobacteria	Streptophyta	(S,S)-butanediol dehydrogenase activity [GO:0047512]; diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]; acetoin catabolic process [GO:0045150]; acetoin metabolic process [GO:0045149]; butanediol metabolic process [GO:0034077]; protein homotetramerization [GO:0051289]	cell wall [GO:0005618]; nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]; L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]	acetoin catabolic process [GO:0045150]; acetoin metabolic process [GO:0045149]; butanediol metabolic process [GO:0034077]; protein homotetramerization [GO:0051289]	L-proline biosynthetic process [GO:0055129]; response to heat [GO:0009408]; response to salt stress [GO:0009651]		cell wall [GO:0005618]	(S,S)-butanediol dehydrogenase activity [GO:0047512]; diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]	nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d3a28g__d3ufxa1__1			Actinobacteria	Deinococcus-Thermus	(S,S)-butanediol dehydrogenase activity [GO:0047512]; diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]; acetoin catabolic process [GO:0045150]; acetoin metabolic process [GO:0045149]; butanediol metabolic process [GO:0034077]; protein homotetramerization [GO:0051289]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; tricarboxylic acid cycle [GO:0006099]	acetoin catabolic process [GO:0045150]; acetoin metabolic process [GO:0045149]; butanediol metabolic process [GO:0034077]; protein homotetramerization [GO:0051289]	tricarboxylic acid cycle [GO:0006099]			(S,S)-butanediol dehydrogenase activity [GO:0047512]; diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]
d3a28h__d2i9pb1__1		Metazoa	Actinobacteria	Chordata	(S,S)-butanediol dehydrogenase activity [GO:0047512]; diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]; acetoin catabolic process [GO:0045150]; acetoin metabolic process [GO:0045149]; butanediol metabolic process [GO:0034077]; protein homotetramerization [GO:0051289]	mitochondrial matrix [GO:0005759]; 3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574]	acetoin catabolic process [GO:0045150]; acetoin metabolic process [GO:0045149]; butanediol metabolic process [GO:0034077]; protein homotetramerization [GO:0051289]	branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574]		mitochondrial matrix [GO:0005759]	(S,S)-butanediol dehydrogenase activity [GO:0047512]; diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3a2la__d2edca___1			Proteobacteria	Proteobacteria	haloalkane dehalogenase activity [GO:0018786]; identical protein binding [GO:0042802]	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]		1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]			haloalkane dehalogenase activity [GO:0018786]; identical protein binding [GO:0042802]	haloalkane dehalogenase activity [GO:0018786]
d3a2ma__d3haca2__1		Metazoa	Proteobacteria	Chordata	haloalkane dehalogenase activity [GO:0018786]; identical protein binding [GO:0042802]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	haloalkane dehalogenase activity [GO:0018786]; identical protein binding [GO:0042802]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3a2mb__d5a62a___1			Proteobacteria	Thaumarchaeota	haloalkane dehalogenase activity [GO:0018786]; identical protein binding [GO:0042802]	hydrolase activity [GO:0016787]					haloalkane dehalogenase activity [GO:0018786]; identical protein binding [GO:0042802]	hydrolase activity [GO:0016787]
d3a2ob__d1ente___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3a2ob__d3spkb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]
d3a2va__d5a4ua1__1		Viridiplantae	Crenarchaeota	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell [GO:0005623]; cytoplasm [GO:0005737]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d3a2vc__d1w4vd1__1		Metazoa	Crenarchaeota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein disulfide oxidoreductase activity [GO:0015035]; protein-containing complex binding [GO:0044877]; cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein-containing complex binding [GO:0044877]; protein disulfide oxidoreductase activity [GO:0015035]
d3a2vd__d1yf1i___1			Crenarchaeota	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	thioredoxin peroxidase activity [GO:0008379]
d3a2vd__d1zcpa___1			Crenarchaeota	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d3a2vf__d5a4uc1__1		Viridiplantae	Crenarchaeota	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell [GO:0005623]; cytoplasm [GO:0005737]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d3a2vg__d1xxuc___1			Crenarchaeota	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; response to nitrosative stress [GO:0051409]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; response to nitrosative stress [GO:0051409]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]
d3a2vg__d2vcrc1__1			Crenarchaeota		cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]		cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]		cell [GO:0005623]; cytoplasm [GO:0005737]		antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	
d3a2wc__d2oe0a___1		Fungi	Crenarchaeota	Ascomycota	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; mitochondrion [GO:0005739]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; mitochondrion [GO:0005739]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]
d3a2wf__d4kw6c___1		Metazoa	Crenarchaeota	Nematoda (roundworms)	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	peroxiredoxin activity [GO:0051920]
d3a2wg__d4chsa1__1		Viridiplantae	Crenarchaeota	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	glutathione transferase activity [GO:0004364]
d3a2wh__d5b8bd___1		Metazoa	Crenarchaeota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]; activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]
d3a2xa__d2fwga2__1			Crenarchaeota	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]; electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; cellular response to temperature stimulus [GO:0071502]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	electron transfer activity [GO:0009055]; oxidoreductase activity [GO:0016491]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d3a2xb__d3hjpd1__1			Crenarchaeota	Crenarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]
d3a2xc__d12gsb2__1		Metazoa	Crenarchaeota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3a2xd__d1nw2g___1			Crenarchaeota	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	protein disulfide oxidoreductase activity [GO:0015035]
d3a2xf__d2vcrd1__1			Crenarchaeota		cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]		cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]		cell [GO:0005623]; cytoplasm [GO:0005737]		antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	
d3a2xg__d2gzza___1			Crenarchaeota	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d3a2xh__d1guma2__1		Metazoa	Crenarchaeota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytosol [GO:0005829]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3a2xi__d1k3lb2__1		Metazoa	Crenarchaeota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3a2xi__d2h1ba___1			Crenarchaeota	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]
d3a3ja2_d3mzfa2__1			Proteobacteria	Proteobacteria	plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	integral component of plasma membrane [GO:0005887]; beta-lactamase activity [GO:0008800]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall macromolecule metabolic process [GO:0044036]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan metabolic process [GO:0000270]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell wall macromolecule metabolic process [GO:0044036]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan metabolic process [GO:0000270]; regulation of cell shape [GO:0008360]	plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]	endopeptidase activity [GO:0004175]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]	beta-lactamase activity [GO:0008800]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]
d3a3ka__d4n0qd___1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; guanylate cyclase activity [GO:0004383]; natriuretic peptide receptor activity [GO:0016941]; peptide hormone binding [GO:0017046]; peptide receptor activity [GO:0001653]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165]	amino acid transport [GO:0006865]	cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP-mediated signaling [GO:0010753]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165]	amino acid transport [GO:0006865]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; GTP binding [GO:0005525]; guanylate cyclase activity [GO:0004383]; natriuretic peptide receptor activity [GO:0016941]; peptide hormone binding [GO:0017046]; peptide receptor activity [GO:0001653]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]	
d3a3qa__d3iwrb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; polysaccharide catabolic process [GO:0000272]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; polysaccharide catabolic process [GO:0000272]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d3a3te1_d3hjma1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3a3ya2_d4uu0a2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; ion channel regulator activity [GO:0099106]; ion transport [GO:0006811]; regulation of ion transport [GO:0043269]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	ion transport [GO:0006811]; regulation of ion transport [GO:0043269]	calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]	ion channel regulator activity [GO:0099106]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]
d3a4fa__d3dgdb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3a4fa__d3iwub___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d3a4ib2_d1gpmc3__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; pyrophosphatase activity [GO:0016462]	cytosol [GO:0005829]; ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; GMP synthase activity [GO:0003921]; identical protein binding [GO:0042802]; pyrophosphatase activity [GO:0016462]; glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]		glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]		cytosol [GO:0005829]	ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; pyrophosphatase activity [GO:0016462]	ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; GMP synthase activity [GO:0003921]; identical protein binding [GO:0042802]; pyrophosphatase activity [GO:0016462]
d3a4ra1_d4bksd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; cytokine production [GO:0001816]; positive regulation of transcription by RNA polymerase II [GO:0045944]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytokine production [GO:0001816]; positive regulation of transcription by RNA polymerase II [GO:0045944]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]		ubiquitin protein ligase binding [GO:0031625]
d3a4ra1_d5chvd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; cytokine production [GO:0001816]; positive regulation of transcription by RNA polymerase II [GO:0045944]	cytosol [GO:0005829]; nucleus [GO:0005634]; cysteine-type endopeptidase activity [GO:0004197]; ISG15-specific protease activity [GO:0019785]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; protein deubiquitination [GO:0016579]; regulation of inflammatory response [GO:0050727]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytokine production [GO:0001816]; positive regulation of transcription by RNA polymerase II [GO:0045944]	protein deubiquitination [GO:0016579]; regulation of inflammatory response [GO:0050727]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; nucleus [GO:0005634]		cysteine-type endopeptidase activity [GO:0004197]; ISG15-specific protease activity [GO:0019785]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]
d3a4va__d5hs6a1__1		Metazoa	Euryarchaeota	Chordata	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]		estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]		cytosol [GO:0005829]	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]
d3a4vb__d1geef___1			Euryarchaeota	Firmicutes	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]			catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]
d3a4ya__d3ie1a___1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	rRNA processing [GO:0006364]	rRNA processing [GO:0006364]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3a4yb__d1ddka___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	rRNA processing [GO:0006364]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d3a4yb__d3ie0b___1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	rRNA processing [GO:0006364]	rRNA processing [GO:0006364]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3a4yc__d1ycfb2__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	rRNA processing [GO:0006364]		cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d3a4yd__d2ynwb___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	metal ion binding [GO:0046872]	rRNA processing [GO:0006364]		cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	metal ion binding [GO:0046872]
d3a4zc__d1f4ub___1			Actinobacteria	Crenarchaeota	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]
d3a50e__d5b2xa___1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d3a51b__d4dnzb___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]			cytoplasm [GO:0005737]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3a58b__d2gila___1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; exocyst [GO:0000145]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; prospore membrane [GO:0005628]; GTP-Rho binding [GO:0017049]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; endoplasmic reticulum inheritance [GO:0048309]; exocyst assembly [GO:0001927]; exocyst localization [GO:0051601]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031]; vesicle tethering involved in exocytosis [GO:0090522]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin V binding [GO:0031489]; protein domain specific binding [GO:0019904]; antigen processing and presentation [GO:0019882]; early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; minus-end-directed organelle transport along microtubule [GO:0072385]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine methylation [GO:0018125]; protein localization to Golgi apparatus [GO:0034067]; Rab protein signal transduction [GO:0032482]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; viral process [GO:0016032]	endoplasmic reticulum inheritance [GO:0048309]; exocyst assembly [GO:0001927]; exocyst localization [GO:0051601]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031]; vesicle tethering involved in exocytosis [GO:0090522]	antigen processing and presentation [GO:0019882]; early endosome to Golgi transport [GO:0034498]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; minus-end-directed organelle transport along microtubule [GO:0072385]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine methylation [GO:0018125]; protein localization to Golgi apparatus [GO:0034067]; Rab protein signal transduction [GO:0032482]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; viral process [GO:0016032]	cell [GO:0005623]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; exocyst [GO:0000145]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; prospore membrane [GO:0005628]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]	GTP-Rho binding [GO:0017049]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin V binding [GO:0031489]; protein domain specific binding [GO:0019904]
d3a5ca3_d3ikja2__1			Deinococcus-Thermus	Euryarchaeota	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP binding [GO:0005524]; endonuclease activity [GO:0004519]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]			ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; endonuclease activity [GO:0004519]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3a5cb1_d3gqba1__1			Deinococcus-Thermus	Deinococcus-Thermus	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]			ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3a5cb4_d2jizc3__1		Metazoa	Deinococcus-Thermus	Chordata	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3a5cc1_d3ziad1__1		Fungi	Deinococcus-Thermus	Ascomycota	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3a5cc3_d3j9te3__1		Fungi	Deinococcus-Thermus	Ascomycota	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]		cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]
d3a5cd1_d3zian1__1		Fungi	Deinococcus-Thermus	Ascomycota	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3a5cd3_d3ikja3__1			Deinococcus-Thermus	Euryarchaeota	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP binding [GO:0005524]; endonuclease activity [GO:0004519]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]			ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; endonuclease activity [GO:0004519]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3a5ce1_d3j9tf1__1		Fungi	Deinococcus-Thermus	Ascomycota	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]		cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]
d3a5cf3_d3j9tb3__1		Fungi	Deinococcus-Thermus	Ascomycota	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]		cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]
d3a5ci1_d2hldx1__1		Fungi	Deinococcus-Thermus	Ascomycota	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3a5ck1_d3gqbc1__1			Deinococcus-Thermus	Deinococcus-Thermus	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]			ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3a5cl3_d3a5cj4__1			Deinococcus-Thermus	Deinococcus-Thermus	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]			ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3a5cn1_d2jj2e1__1		Metazoa	Deinococcus-Thermus	Chordata	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3a5lc2_d5aqoc2__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3a5ls__d1m4jb___1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; filopodium [GO:0030175]; myofibril [GO:0030016]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; actin filament depolymerization [GO:0030042]; barbed-end actin filament capping [GO:0051016]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of neuron projection development [GO:0010976]; regulation of actin phosphorylation [GO:0043538]; regulation of lamellipodium assembly [GO:0010591]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament depolymerization [GO:0030042]; barbed-end actin filament capping [GO:0051016]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of neuron projection development [GO:0010976]; regulation of actin phosphorylation [GO:0043538]; regulation of lamellipodium assembly [GO:0010591]; sequestering of actin monomers [GO:0042989]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; filopodium [GO:0030175]; myofibril [GO:0030016]; perinuclear region of cytoplasm [GO:0048471]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]
d3a5ls__d2fh2b2__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d3a5ms__d2fh4b3__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d3a5ns__d2fgha5__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d3a5os__d1d0na5__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d3a5os__d1vfqa2__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; site of polarized growth [GO:0030427]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]; defense response to fungus [GO:0050832]; neutrophil degranulation [GO:0043312]; regulation of actin filament polymerization [GO:0030833]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	defense response to fungus [GO:0050832]; neutrophil degranulation [GO:0043312]; regulation of actin filament polymerization [GO:0030833]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; site of polarized growth [GO:0030427]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]
d3a5qb1_d1xpkd2__1	Viridiplantae		Streptophyta	Firmicutes	protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]; protein-chromophore linkage [GO:0018298]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	flavonoid biosynthetic process [GO:0009813]; protein-chromophore linkage [GO:0018298]	isoprenoid biosynthetic process [GO:0008299]			protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d3a5qb2_d4nhdd2__1	Viridiplantae		Streptophyta	Proteobacteria	protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	flavonoid biosynthetic process [GO:0009813]; protein-chromophore linkage [GO:0018298]	fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]	protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d3a5rb2_d2vu0a2__1	Viridiplantae		Streptophyta	Proteobacteria	protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	flavonoid biosynthetic process [GO:0009813]; protein-chromophore linkage [GO:0018298]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3a5wb__d1vf3b1__1		Metazoa	Crenarchaeota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	glutathione transferase activity [GO:0004364]
d3a5wd__d3a2vc___1			Crenarchaeota	Crenarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d3a5wh__d3tkqa___1		Metazoa	Crenarchaeota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d3a5wi__d1oc8b___1			Crenarchaeota		cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	
d3a5zb1_d3hksb1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; acid-ammonia (or amide) ligase activity [GO:0016880]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; protein-lysine lysyltransferase activity [GO:0052868]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; protein-lysine lysylation [GO:0071915]; protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine [GO:0072581]	cytosol [GO:0005829]; nucleus [GO:0005634]; ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; defense response to bacterium [GO:0042742]; host programmed cell death induced by symbiont [GO:0034050]; positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; programmed cell death [GO:0012501]; response to bacterium [GO:0009617]; response to cadmium ion [GO:0046686]; response to wounding [GO:0009611]; translational frameshifting [GO:0006452]; translational initiation [GO:0006413]	lysyl-tRNA aminoacylation [GO:0006430]; protein-lysine lysylation [GO:0071915]; protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine [GO:0072581]	defense response to bacterium [GO:0042742]; host programmed cell death induced by symbiont [GO:0034050]; positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; programmed cell death [GO:0012501]; response to bacterium [GO:0009617]; response to cadmium ion [GO:0046686]; response to wounding [GO:0009611]; translational frameshifting [GO:0006452]; translational initiation [GO:0006413]	cytosol [GO:0005829]	cytosol [GO:0005829]; nucleus [GO:0005634]	acid-ammonia (or amide) ligase activity [GO:0016880]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; protein-lysine lysyltransferase activity [GO:0052868]; tRNA binding [GO:0000049]	ribosome binding [GO:0043022]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d3a67h__d1u2ha___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	nucleus [GO:0005634]; ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; cardiovascular system development [GO:0072358]; muscle cell differentiation [GO:0042692]; muscle organ development [GO:0007517]; negative regulation of cell population proliferation [GO:0008285]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cardiovascular system development [GO:0072358]; muscle cell differentiation [GO:0042692]; muscle organ development [GO:0007517]; negative regulation of cell population proliferation [GO:0008285]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	nucleus [GO:0005634]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d3a67l__d4hzlb2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3a68c__d1f33l___1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3a68f__d3uoix___1	Viridiplantae		Streptophyta	Actinobacteria	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3a68f__d4tw3a___1	Viridiplantae		Streptophyta	Cyanobacteria	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]
d3a68h__d2vxie___1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3a68o__d2xjoe___1	Viridiplantae		Streptophyta	Firmicutes	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d3a68t__d3hx2q1__1	Viridiplantae		Streptophyta		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	
d3a68w__d1nfvh___1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3a68x__d1oq4a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	chloroplast [GO:0009507]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d3a6bl__d1j05b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d3a6bl__d4m6ol2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d3a6by__d2z37c___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d3a6ch__d1lo3l2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d3a6cy__d3c7za___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3a6ec__d3a6db___1			Proteobacteria	Proteobacteria	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]			creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]
d3a6ga__d1j2ta___1			Proteobacteria	Proteobacteria	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]			creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]
d3a6la__d1q3ka___1			Proteobacteria	Proteobacteria	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]			creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]
d3a6lc__d3a6ff___1			Proteobacteria	Proteobacteria	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]			creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]
d3a6le__d3a6fe___1			Proteobacteria	Proteobacteria	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]; creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]	creatine biosynthetic process [GO:0006601]; creatinine catabolic process [GO:0006602]			creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]	creatininase activity [GO:0047789]; manganese ion binding [GO:0030145]; zinc ion binding [GO:0008270]
d3a6nf__d3av1e___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of protein oligomerization [GO:0032460]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; telomere capping [GO:0016233]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of protein oligomerization [GO:0032460]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; telomere capping [GO:0016233]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3a6nh__d3b6gc1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of protein oligomerization [GO:0032460]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; telomere capping [GO:0016233]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of protein oligomerization [GO:0032460]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; telomere capping [GO:0016233]		extracellular exosome [GO:0070062]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3a6ob3_d4puea___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]	endo-1,4-beta-xylanase activity [GO:0031176]
d3a6qa__d5choh___1			Proteobacteria		cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	FMN binding [GO:0010181]	oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]		cofactor binding [GO:0048037]	FMN binding [GO:0010181]
d3a6qb__d1wlia___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	cofactor binding [GO:0048037]	cofactor binding [GO:0048037]
d3a6qb__d4ybna___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]		cofactor binding [GO:0048037]	cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d3a6rc__d3cb0b___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	4-hydroxyphenylacetate 3-monooxygenase activity [GO:0052881]; FMN binding [GO:0010181]	oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]		cofactor binding [GO:0048037]	4-hydroxyphenylacetate 3-monooxygenase activity [GO:0052881]; FMN binding [GO:0010181]
d3a6ua__d5ghpb___1		Metazoa	Proteobacteria	Chordata	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTP diphosphatase activity [GO:0036219]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]; aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTPase activity [GO:0003924]; GTP diphosphatase activity [GO:0036219]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]
d3a73b1_d5orfa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d3a74a1_d1b8ab1__1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	lysyl-tRNA aminoacylation [GO:0006430]	aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d3a74c1_d1eqrc1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]; aspartyl-tRNA aminoacylation [GO:0006422]	lysyl-tRNA aminoacylation [GO:0006430]	aspartyl-tRNA aminoacylation [GO:0006422]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; nucleic acid binding [GO:0003676]
d3a74d1_d1krsa___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	lysyl-tRNA aminoacylation [GO:0006430]	lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]
d3a74d1_d2ja5g1__1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	lysyl-tRNA aminoacylation [GO:0006430]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]
d3a7ad__d3ifta1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; lipoate-protein ligase activity [GO:0016979]; lipoyltransferase activity [GO:0017118]; protein lipoylation [GO:0009249]	glycine cleavage complex [GO:0005960]; glycine decarboxylation via glycine cleavage system [GO:0019464]	protein lipoylation [GO:0009249]	glycine decarboxylation via glycine cleavage system [GO:0019464]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	glycine cleavage complex [GO:0005960]	ATP binding [GO:0005524]; lipoate-protein ligase activity [GO:0016979]; lipoyltransferase activity [GO:0017118]	
d3a7da__d5p93a___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d3a7xa__d6cha.2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3a7ya__d1bmm.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d3a84a__d4proa___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d3a86a__d2aiqa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]
d3a89a__d3zz7a1__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3a8ib1_d1pj5a4__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]; lipoic acid binding [GO:0031405]; glycine decarboxylation via glycine cleavage system [GO:0019464]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	glycine decarboxylation via glycine cleavage system [GO:0019464]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]		lipoic acid binding [GO:0031405]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]
d3a8ib2_d1wopa1__1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]; lipoic acid binding [GO:0031405]; glycine decarboxylation via glycine cleavage system [GO:0019464]	cytosol [GO:0005829]; aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]; glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]	cytosol [GO:0005829]	lipoic acid binding [GO:0031405]	aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]
d3a8ic2_d1wosa1__1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]; lipoic acid binding [GO:0031405]; glycine decarboxylation via glycine cleavage system [GO:0019464]	cytosol [GO:0005829]; aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]; glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]	cytosol [GO:0005829]	lipoic acid binding [GO:0031405]	aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]
d3a8ja2_d1pj7a1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]; lipoic acid binding [GO:0031405]; glycine decarboxylation via glycine cleavage system [GO:0019464]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	glycine decarboxylation via glycine cleavage system [GO:0019464]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]		lipoic acid binding [GO:0031405]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]
d3a8jb2_d1pj6a1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]; lipoic acid binding [GO:0031405]; glycine decarboxylation via glycine cleavage system [GO:0019464]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	glycine decarboxylation via glycine cleavage system [GO:0019464]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]		lipoic acid binding [GO:0031405]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]
d3a8jd2_d1v5vb1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]; lipoic acid binding [GO:0031405]; glycine decarboxylation via glycine cleavage system [GO:0019464]	aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]; glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]		lipoic acid binding [GO:0031405]	aminomethyltransferase activity [GO:0004047]; transaminase activity [GO:0008483]
d3a8kc2_d1pj5a1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]; lipoic acid binding [GO:0031405]; glycine decarboxylation via glycine cleavage system [GO:0019464]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]	glycine decarboxylation via glycine cleavage system [GO:0019464]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]		lipoic acid binding [GO:0031405]	dimethylglycine oxidase activity [GO:0047866]; nucleotide binding [GO:0000166]
d3a8kd1_d3a8jc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]; lipoic acid binding [GO:0031405]; glycine decarboxylation via glycine cleavage system [GO:0019464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]; lipoic acid binding [GO:0031405]; glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	glycine decarboxylation via glycine cleavage system [GO:0019464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycine cleavage complex [GO:0005960]	lipoic acid binding [GO:0031405]	lipoic acid binding [GO:0031405]
d3a8ob__d4ob2b___1			Actinobacteria	Actinobacteria	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; nitrile hydratase activity [GO:0018822]; transition metal ion binding [GO:0046914]; nitrile catabolic process [GO:0050899]	nitrogen compound metabolic process [GO:0006807]	nitrile catabolic process [GO:0050899]			indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; nitrile hydratase activity [GO:0018822]; transition metal ion binding [GO:0046914]
d3a92a__d4i7sb1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3a93a__d3htga___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3a9ja__d5xada___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d3a9ka__d3b08j1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d3a9kb__d5aekj___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d3a9qc__d3pw1c1__1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cytosol [GO:0005829]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	
d3a9qg__d3rgdj___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3a9qi__d1b71a1__1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3a9qi__d5l89b___1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	metal ion binding [GO:0046872]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	metal ion binding [GO:0046872]
d3a9qm__d4xktc___1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3a9qn__d5d8xd___1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3a9qo__d1f30l___1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3a9qo__d4cmyn___1	Viridiplantae		Streptophyta	Chlorobi	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]
d3a9qp__d1tk6b___1	Viridiplantae		Streptophyta	Euryarchaeota	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d3a9qv__d4to9w___1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3a9qx__d4dasq___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3a9rb1_d1fuif2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytosol [GO:0005829]; arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	L-fucose catabolic process [GO:0042355]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]
d3a9rb2_d2ajtb1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytosol [GO:0005829]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	L-fucose catabolic process [GO:0042355]	arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d3a9sa2_d2ajta1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytosol [GO:0005829]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	L-fucose catabolic process [GO:0042355]	arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d3a9sc2_d1fuif1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytosol [GO:0005829]; arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	L-fucose catabolic process [GO:0042355]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]
d3a9sc2_d4c21b2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	L-fucose catabolic process [GO:0042355]	L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]
d3a9ta2_d4r1of2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	L-fucose catabolic process [GO:0042355]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d3a9tc1_d2hxgb2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytosol [GO:0005829]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	L-fucose catabolic process [GO:0042355]	arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d3a9wb__d1up7a1__1			Euryarchaeota	Thermotogae	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3aa2a__d4ig0a2__1			Proteobacteria		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3aa9b__d3ta1f1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; metal ion binding [GO:0046872]; protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]	protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	regulation of nitrogen utilization [GO:0006808]	cytoplasm [GO:0005737]		copper ion binding [GO:0005507]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]
d3aabb__d3w1zd___1		Fungi	Crenarchaeota	Ascomycota		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to misfolded protein [GO:0071218]; cellular response to unfolded protein [GO:0034620]; chaperone-mediated protein folding [GO:0061077]		cellular response to heat [GO:0034605]; cellular response to misfolded protein [GO:0071218]; cellular response to unfolded protein [GO:0034620]; chaperone-mediated protein folding [GO:0061077]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]
d3aacb__d4ylca1__1			Crenarchaeota	Crenarchaeota		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]						identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3aama__d5nhad___1		Fungi	Deinococcus-Thermus	Chytridiomycota	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; zinc ion binding [GO:0008270]; DNA repair [GO:0006281]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	DNA repair [GO:0006281]	xylose catabolic process to ethanol [GO:0044577]			DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d3aaua__d2ei8a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d3aava__d1thp.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d3aavb__d3zz9a1__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3aazl2_d4kfzc___1		Metazoa		Chordata		nucleoplasm [GO:0005654]; transcription factor complex [GO:0005667]; bHLH transcription factor binding [GO:0043425]; cofactor binding [GO:0048037]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; E-box binding [GO:0070888]; metal ion binding [GO:0046872]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cellular response to thyroid hormone stimulus [GO:0097067]; mRNA transcription by RNA polymerase II [GO:0042789]; multicellular organism development [GO:0007275]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hematopoietic stem cell differentiation [GO:1902036]		cellular response to thyroid hormone stimulus [GO:0097067]; mRNA transcription by RNA polymerase II [GO:0042789]; multicellular organism development [GO:0007275]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hematopoietic stem cell differentiation [GO:1902036]		nucleoplasm [GO:0005654]; transcription factor complex [GO:0005667]		bHLH transcription factor binding [GO:0043425]; cofactor binding [GO:0048037]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; E-box binding [GO:0070888]; metal ion binding [GO:0046872]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d3ab0b__d3levl2__1	Metazoa		Chordata	Deinococcus-Thermus	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]; transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytoplasm [GO:0005737]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]
d3ab0c__d4l3ck2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ab0f__d2dqfa___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3ab5b__d1n60d2__1			Rhodophyta	Proteobacteria	chloroplast [GO:0009507]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]			chloroplast [GO:0009507]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3abaa1_d3a50d___1			Actinobacteria	Actinobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3abaa1_d5ibga___1			Actinobacteria	Actinobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]
d3ablo2_d2xx0a1__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	ATP synthesis coupled electron transport [GO:0042773]	nitrogen compound metabolic process [GO:0006807]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]		copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3abmo2_d2ftac___1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	ATP synthesis coupled electron transport [GO:0042773]	oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3abmo2_d4gp5b2__1	Metazoa		Chordata	Deinococcus-Thermus	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d3abza3_d4ai1a1__1	Fungi	Fungi	Ascomycota	Ascomycota	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	anchored component of membrane [GO:0031225]; cell periphery [GO:0071944]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; mannose binding [GO:0005537]; cell-substrate adhesion [GO:0031589]; coflocculation [GO:0036281]; flocculation [GO:0000128]; flocculation via cell wall protein-carbohydrate interaction [GO:0000501]	cellulose catabolic process [GO:0030245]	cell-substrate adhesion [GO:0031589]; coflocculation [GO:0036281]; flocculation [GO:0000128]; flocculation via cell wall protein-carbohydrate interaction [GO:0000501]		anchored component of membrane [GO:0031225]; cell periphery [GO:0071944]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	mannose binding [GO:0005537]
d3ac0a1_d2x42a1__1	Fungi		Ascomycota	Thermotogae	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3ac0c1_d2wc4a___1	Fungi		Ascomycota	Thermotogae	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3acga__d3zyfd___1			Firmicutes	Proteobacteria	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	cellulose catabolic process [GO:0030245]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d3acha__d5j1xb___1		Metazoa	Firmicutes	Chordata	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]; coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	cellulose catabolic process [GO:0030245]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]	coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d3acla__d4xffa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; quercetin 2,3-dioxygenase activity [GO:0008127]; transcription coregulator activity [GO:0003712]; digestion [GO:0007586]; monocyte differentiation [GO:0030224]; transcription by RNA polymerase II [GO:0006366]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	digestion [GO:0007586]; monocyte differentiation [GO:0030224]; transcription by RNA polymerase II [GO:0006366]	cysteine metabolic process [GO:0006534]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]	metal ion binding [GO:0046872]; quercetin 2,3-dioxygenase activity [GO:0008127]; transcription coregulator activity [GO:0003712]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d3ae1b1_d4kx6n1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane fumarate reductase complex [GO:0045284]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; fumarate metabolic process [GO:0006106]	mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; fumarate metabolic process [GO:0006106]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane fumarate reductase complex [GO:0045284]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d3ae1b1_d4xdca1__1	Metazoa		Chordata	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]	mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]		mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]
d3ae1b2_d1gted1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d3ae4b1_d4zhob1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	chloroplast [GO:0009507]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; photosynthetic acclimation [GO:0009643]; photosynthetic electron transport chain [GO:0009767]	mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	photosynthetic acclimation [GO:0009643]; photosynthetic electron transport chain [GO:0009767]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	chloroplast [GO:0009507]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3aebb1_d2mjea___1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; heme a biosynthetic process [GO:0006784]; iron-sulfur cluster assembly [GO:0016226]; ubiquinone biosynthetic process [GO:0006744]	mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	heme a biosynthetic process [GO:0006784]; iron-sulfur cluster assembly [GO:0016226]; ubiquinone biosynthetic process [GO:0006744]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	mitochondrial matrix [GO:0005759]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d3aefb2_d4ysxb2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d3aejb__d1o62a___1				Proteobacteria	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	transaminase activity [GO:0008483]	transsulfuration [GO:0019346]				methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]	transaminase activity [GO:0008483]
d3aeoc__d3e2zb___1		Metazoa		Chordata	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; kynurenine-glyoxylate transaminase activity [GO:0047315]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]; kynurenine metabolic process [GO:0070189]	transsulfuration [GO:0019346]	2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]; kynurenine metabolic process [GO:0070189]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]	cysteine-S-conjugate beta-lyase activity [GO:0047804]; kynurenine-glyoxylate transaminase activity [GO:0047315]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]
d3aepb__d1elqb___1				Cyanobacteria	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	lyase activity [GO:0016829]	transsulfuration [GO:0019346]				methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]	lyase activity [GO:0016829]
d3aexb__d5d85a___1			Deinococcus-Thermus	Firmicutes	pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]; threonine biosynthetic process [GO:0009088]	transferase activity [GO:0016740]; cysteine biosynthetic process from serine [GO:0006535]	threonine biosynthetic process [GO:0009088]	cysteine biosynthetic process from serine [GO:0006535]			pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]	transferase activity [GO:0016740]
d3aeza__d2jdif3__1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	coenzyme A biosynthetic process [GO:0015937]	ATP synthesis coupled proton transport [GO:0015986]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3af1a__d4dcna___1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; trans-Golgi network membrane [GO:0032588]; cadherin binding [GO:0045296]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phospholipid binding [GO:0005543]; protein domain specific binding [GO:0019904]; Rac GTPase binding [GO:0048365]; actin cytoskeleton organization [GO:0030036]; autophagy [GO:0006914]; intracellular protein transport [GO:0006886]; lamellipodium assembly [GO:0030032]; ruffle organization [GO:0031529]; small GTPase mediated signal transduction [GO:0007264]	coenzyme A biosynthetic process [GO:0015937]	actin cytoskeleton organization [GO:0030036]; autophagy [GO:0006914]; intracellular protein transport [GO:0006886]; lamellipodium assembly [GO:0030032]; ruffle organization [GO:0031529]; small GTPase mediated signal transduction [GO:0007264]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; trans-Golgi network membrane [GO:0032588]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]	cadherin binding [GO:0045296]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phospholipid binding [GO:0005543]; protein domain specific binding [GO:0019904]; Rac GTPase binding [GO:0048365]
d3af9x__d2jd7l___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]
d3afaa__d1kx5b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3afac__d3mgrc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3afad__d2nqbg___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromatin organization [GO:0006325]; larval somatic muscle development [GO:0007526]; nucleosome assembly [GO:0006334]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	chromosome [GO:0005694]; nuclear chromatin [GO:0000790]; nuclear nucleosome [GO:0000788]; nucleosome [GO:0000786]; nucleus [GO:0005634]; polytene chromosome [GO:0005700]; polytene chromosome band [GO:0005704]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3afha1_d2dxia2__1			Thermotogae	Deinococcus-Thermus	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	glutamyl-tRNA aminoacylation [GO:0006424]	glutamyl-tRNA aminoacylation [GO:0006424]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d3afha2_d1n78b1__1			Thermotogae	Deinococcus-Thermus	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	glutamyl-tRNA aminoacylation [GO:0006424]	glutamyl-tRNA aminoacylation [GO:0006424]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d3afkb1_d1ww5a___1	Fungi	Fungi	Basidiomycota	Basidiomycota	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d3afnd__d3vzrb___1			Proteobacteria	Proteobacteria	nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; acetoacetyl-CoA reductase activity [GO:0018454]; poly-hydroxybutyrate biosynthetic process [GO:0042619]		poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	nucleotide binding [GO:0000166]	acetoacetyl-CoA reductase activity [GO:0018454]
d3ag2b2_d3qjqb2__1	Metazoa		Chordata	Deinococcus-Thermus	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d3ag2o2_d1asoa1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	extracellular region [GO:0005576]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]
d3ag3b2_d4dp1x___1	Metazoa	Viridiplantae	Chordata	Streptophyta	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3ag4o2_d3fu9b2__1	Metazoa	Fungi	Chordata	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	ATP synthesis coupled electron transport [GO:0042773]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3agha__d1c62a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3agha__d1hfya___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; lactose biosynthetic process [GO:0005989]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	lactose biosynthetic process [GO:0005989]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]
d3agja4_d5l3sg2__1				Crenarchaeota		signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]		SRP-dependent cotranslational protein targeting to membrane [GO:0006614]		signal recognition particle [GO:0048500]		7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d3agja5_d1aipa1__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3agjc4_d1ko5a___1				Proteobacteria		ATP binding [GO:0005524]; gluconokinase activity [GO:0046316]; D-gluconate catabolic process [GO:0046177]		D-gluconate catabolic process [GO:0046177]				ATP binding [GO:0005524]; gluconokinase activity [GO:0046316]
d3agjc5_d4lbwa2__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3agjg5_d2rdod1__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribosomal large subunit binding [GO:0043023]; cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasmic translational termination [GO:0002184]; translation [GO:0006412]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		ribosomal large subunit binding [GO:0043023]
d3agna__d1trpa___1	Fungi	Fungi	Basidiomycota	Ascomycota	endoribonuclease activity [GO:0004521]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]				cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d3agva2_d5o0wg1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	glycolytic process [GO:0006096]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	fructose-bisphosphate aldolase activity [GO:0004332]
d3agvb2_d3ebaa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3agxa1_d2b26b2__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; sperm head [GO:0061827]; ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; protein folding chaperone [GO:0044183]; transcription corepressor activity [GO:0003714]; unfolded protein binding [GO:0051082]; chaperone cofactor-dependent protein refolding [GO:0051085]; forebrain development [GO:0030900]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; positive regulation of ATPase activity [GO:0032781]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]	cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; nucleus [GO:0005634]; chaperone binding [GO:0051087]; DNA binding [GO:0003677]; misfolded protein binding [GO:0051787]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; chaperone cofactor-dependent protein refolding [GO:0051085]; misfolded protein transport [GO:0070843]; nuclear protein quality control by the ubiquitin-proteasome system [GO:0071630]; protein folding [GO:0006457]; translational initiation [GO:0006413]; tRNA import into nucleus [GO:0035719]	chaperone cofactor-dependent protein refolding [GO:0051085]; forebrain development [GO:0030900]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; positive regulation of ATPase activity [GO:0032781]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]	cell cycle [GO:0007049]; chaperone cofactor-dependent protein refolding [GO:0051085]; misfolded protein transport [GO:0070843]; nuclear protein quality control by the ubiquitin-proteasome system [GO:0071630]; protein folding [GO:0006457]; translational initiation [GO:0006413]; tRNA import into nucleus [GO:0035719]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; sperm head [GO:0061827]	cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; nucleus [GO:0005634]	ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; protein folding chaperone [GO:0044183]; transcription corepressor activity [GO:0003714]; unfolded protein binding [GO:0051082]	chaperone binding [GO:0051087]; DNA binding [GO:0003677]; misfolded protein binding [GO:0051787]; unfolded protein binding [GO:0051082]
d3agxa2_d2b26a2__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; sperm head [GO:0061827]; ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; protein folding chaperone [GO:0044183]; transcription corepressor activity [GO:0003714]; unfolded protein binding [GO:0051082]; chaperone cofactor-dependent protein refolding [GO:0051085]; forebrain development [GO:0030900]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; positive regulation of ATPase activity [GO:0032781]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]	cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; nucleus [GO:0005634]; chaperone binding [GO:0051087]; DNA binding [GO:0003677]; misfolded protein binding [GO:0051787]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; chaperone cofactor-dependent protein refolding [GO:0051085]; misfolded protein transport [GO:0070843]; nuclear protein quality control by the ubiquitin-proteasome system [GO:0071630]; protein folding [GO:0006457]; translational initiation [GO:0006413]; tRNA import into nucleus [GO:0035719]	chaperone cofactor-dependent protein refolding [GO:0051085]; forebrain development [GO:0030900]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; positive regulation of ATPase activity [GO:0032781]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]	cell cycle [GO:0007049]; chaperone cofactor-dependent protein refolding [GO:0051085]; misfolded protein transport [GO:0070843]; nuclear protein quality control by the ubiquitin-proteasome system [GO:0071630]; protein folding [GO:0006457]; translational initiation [GO:0006413]; tRNA import into nucleus [GO:0035719]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; sperm head [GO:0061827]	cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; nucleus [GO:0005634]	ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; protein folding chaperone [GO:0044183]; transcription corepressor activity [GO:0003714]; unfolded protein binding [GO:0051082]	chaperone binding [GO:0051087]; DNA binding [GO:0003677]; misfolded protein binding [GO:0051787]; unfolded protein binding [GO:0051082]
d3ah1b1_d3ca4a2__1		Viridiplantae		Streptophyta	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	pathogenesis [GO:0009405]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3ah1b2_d4lo1a2__1				Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]	
d3ah3d__d2y41a1__1			Deinococcus-Thermus	Deinococcus-Thermus	homoisocitrate dehydrogenase activity [GO:0047046]; metal ion binding [GO:0046872]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	lysine biosynthetic process via aminoadipic acid [GO:0019878]	leucine biosynthetic process [GO:0009098]		cytoplasm [GO:0005737]	homoisocitrate dehydrogenase activity [GO:0047046]; metal ion binding [GO:0046872]	3-isopropylmalate dehydrogenase activity [GO:0003862]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d3ah4a1_d1ybib1__1				Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]	
d3ah4a2_d4zlbb2__1		Viridiplantae		Streptophyta	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	pathogenesis [GO:0009405]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3ah8b__d4ia9a___1	Metazoa	Metazoa	Chordata	Chordata	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]
d3ahta__d1ukoa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d3ahtb__d1pz3b2__1	Viridiplantae		Streptophyta	Firmicutes	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	carbohydrate metabolic process [GO:0005975]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	alpha-L-arabinofuranosidase activity [GO:0046556]
d3ahua__d4juvf___1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; RNA binding [GO:0003723]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]; bent DNA binding [GO:0003681]; RNA binding [GO:0003723]; negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]	cytosol [GO:0005829]	RNA binding [GO:0003723]	bent DNA binding [GO:0003681]; RNA binding [GO:0003723]
d3ahva__d3iapa3__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3ahwa__d1brjb___1	Fungi		Basidiomycota	Firmicutes	endoribonuclease activity [GO:0004521]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]				extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d3ahxb__d2zxab1__1			Firmicutes	Thermotogae	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	cellulose catabolic process [GO:0030245]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]		lysosome [GO:0005764]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	alpha-L-fucosidase activity [GO:0004560]
d3ahxc__d1xcwa2__1		Metazoa	Firmicutes	Chordata	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cellulose catabolic process [GO:0030245]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3ahya__d3vd4a3__1	Fungi		Ascomycota	Proteobacteria	beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-glucosidase activity [GO:0008422]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3ahyb1_d3bmva4__1	Fungi		Ascomycota	Firmicutes	beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	beta-glucosidase activity [GO:0008422]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3ai2a__d1rwbb___1			Proteobacteria	Firmicutes	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]			nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]
d3ai2b__d1zmoe___1			Proteobacteria	Actinobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]						nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	
d3ai2f__d4nbua___1			Proteobacteria	Firmicutes	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]					nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3aida__d4auca___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3aidb__d3liza1__1		Metazoa		Arthropoda	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]
d3aiga__d2yigb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]		bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d3aika__d4dtcb2__1		Metazoa	Crenarchaeota	Chordata	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3aikb__d1aqla___1		Metazoa	Crenarchaeota	Chordata	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; presynapse [GO:0098793]; synapse [GO:0045202]; acetylesterase activity [GO:0008126]; neurexin family protein binding [GO:0042043]; signaling receptor activity [GO:0038023]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]; modulation of chemical synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; synaptic vesicle endocytosis [GO:0048488]		lipid catabolic process [GO:0016042]; modulation of chemical synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; synaptic vesicle endocytosis [GO:0048488]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; presynapse [GO:0098793]; synapse [GO:0045202]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	acetylesterase activity [GO:0008126]; neurexin family protein binding [GO:0042043]; signaling receptor activity [GO:0038023]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d3aikc__d1yasa___1		Viridiplantae	Crenarchaeota	Streptophyta	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]					identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]
d3aikd__d1xzla___1		Fungi	Crenarchaeota	Ascomycota	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]				extracellular region [GO:0005576]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	cutinase activity [GO:0050525]
d3aila__d1qoza___1		Fungi	Crenarchaeota	Ascomycota	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	extracellular region [GO:0005576]; acetylxylan esterase activity [GO:0046555]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]		cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	acetylxylan esterase activity [GO:0046555]; cellulose binding [GO:0030248]
d3ailb__d1keza___1			Crenarchaeota	Actinobacteria	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	erythronolide synthase activity [GO:0047879]; hydrolase activity, acting on ester bonds [GO:0016788]; phosphopantetheine binding [GO:0031177]; macrolide biosynthetic process [GO:0033068]		macrolide biosynthetic process [GO:0033068]			identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	erythronolide synthase activity [GO:0047879]; hydrolase activity, acting on ester bonds [GO:0016788]; phosphopantetheine binding [GO:0031177]
d3ailb__d3a2la___1			Crenarchaeota	Proteobacteria	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	haloalkane dehalogenase activity [GO:0018786]; identical protein binding [GO:0042802]					identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	haloalkane dehalogenase activity [GO:0018786]; identical protein binding [GO:0042802]
d3aimc__d4dnfd1__1			Crenarchaeota	Proteobacteria	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	hydrolase activity [GO:0016787]					identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	hydrolase activity [GO:0016787]
d3aina__d1tahd___1			Crenarchaeota	Proteobacteria	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d3aioc__d5xg0a1__1			Crenarchaeota	Proteobacteria	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	extracellular region [GO:0005576]; carboxylic ester hydrolase activity [GO:0052689]; cellular response to organic substance [GO:0071310]; xenobiotic catabolic process [GO:0042178]		cellular response to organic substance [GO:0071310]; xenobiotic catabolic process [GO:0042178]		extracellular region [GO:0005576]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	carboxylic ester hydrolase activity [GO:0052689]
d3aiod__d2bucd2__1		Metazoa	Crenarchaeota	Chordata	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3aira__d1qoxe___1	Viridiplantae		Streptophyta	Firmicutes	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	chloroplast [GO:0009507]		beta-glucosidase activity [GO:0008422]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; scopolin beta-glucosidase activity [GO:0102483]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3aisa__d1bglc5__1	Viridiplantae		Streptophyta		chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		chloroplast [GO:0009507]		beta-glucosidase activity [GO:0008422]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; scopolin beta-glucosidase activity [GO:0102483]	
d3aiwa__d5u3aa1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	chloroplast [GO:0009507]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	beta-glucosidase activity [GO:0008422]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; scopolin beta-glucosidase activity [GO:0102483]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3aixa1_d6ap4h2__1			Crenarchaeota	Proteobacteria	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]		cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d3aizc1_d5f7ie2__1			Crenarchaeota		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]		DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]				DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	
d3aizd1_d1vyje1__1		Metazoa	Crenarchaeota	Chordata	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]		centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d3aizd2_d1czdc1__1			Crenarchaeota		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]			DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	
d3aj5a1_d5bqua1__1				Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]	
d3aj5a2_d4qd2h2__1		Metazoa		Chordata	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	pathogenesis [GO:0009405]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	carbohydrate binding [GO:0030246]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d3aj6a1_d1abrb2__1		Viridiplantae		Streptophyta	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]	galactose binding [GO:0005534]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]; positive regulation of endocytosis [GO:0045807]	pathogenesis [GO:0009405]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]; positive regulation of endocytosis [GO:0045807]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]	galactose binding [GO:0005534]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3aj6a2_d4ouja1__1				Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]	
d3aj6b1_d1onkb2__1		Viridiplantae		Streptophyta	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	pathogenesis [GO:0009405]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3ajpa__d2v15i___1	Metazoa		Chordata	Firmicutes	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d3ajqa__d3pwqb1__1	Metazoa		Chordata	Proteobacteria	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	phenylacetate catabolic process [GO:0010124]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	
d3ajrb__d2wyvd___1			Euryarchaeota	Deinococcus-Thermus	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]			catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d3ak1d1_d1xuqa1__1			Crenarchaeota	Firmicutes	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]			identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ak1d2_d2cdyb2__1			Crenarchaeota	Deinococcus-Thermus	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ak2a2_d4f2na2__1			Crenarchaeota		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ak2c2_d1ztea2__1		Metazoa	Crenarchaeota	Chordata	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ak2c2_d3lioa2__1			Crenarchaeota	Proteobacteria	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ak2d1_d1mmma1__1			Crenarchaeota	Proteobacteria	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ak2d2_d1ar5b2__1			Crenarchaeota	Actinobacteria	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ak3b2_d2bpia2__1			Crenarchaeota	Apicomplexa	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytosol [GO:0005829]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ak3c1_d4f2ne1__1			Crenarchaeota		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ak3c2_d1n0ja2__1		Metazoa	Crenarchaeota	Chordata	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ak3d1_d1gn6b1__1			Crenarchaeota	Actinobacteria	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ak3d2_d2qkaa2__1		Metazoa	Crenarchaeota	Chordata	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ak4d__d1f0ya2__1		Metazoa	Proteobacteria	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d3ak8c__d2xjod___1				Firmicutes		cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d3ak8f__d3a9qr___1		Viridiplantae		Streptophyta		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3ak8g__d1oqbb___1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		chloroplast [GO:0009507]		acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d3ak8j__d1jtsm___1				Proteobacteria		cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]		cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]		cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3ak8j__d4bmta___1				Firmicutes		integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]		metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3ak9b__d1z6ot___1		Metazoa		Arthropoda		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3ak9d__d2vxxc___1				Cyanobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3ak9d__d3e1ph___1				Proteobacteria		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3ak9h__d4toaq___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3ak9i__d4v0jb___1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		chloroplast [GO:0009507]		acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d3akmb__d2k62a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	cytoplasm [GO:0005737]; lipid binding [GO:0008289]	intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]	lipid binding [GO:0008289]
d3akmb__d4zhgc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d3akmd__d3ph6a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]		cytosol [GO:0005829]	extracellular region [GO:0005576]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]
d3akra__d1oa2b___1	Fungi	Fungi	Ascomycota	Ascomycota	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			endo-1,4-beta-xylanase activity [GO:0031176]	cellulase activity [GO:0008810]
d3akta__d1rira___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3al4c__d2wrgj___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3al4g__d2wrcc1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3al4k__d5vtre1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d3alsa__d3ncwd2__1	Metazoa		Echinodermata	Proteobacteria	metal ion binding [GO:0046872]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]	
d3alsc__d4g96d___1	Metazoa	Metazoa	Echinodermata	Chordata	metal ion binding [GO:0046872]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d3alsd__d1wmzd___1	Metazoa	Metazoa	Echinodermata	Echinodermata	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3altb__d1rjha___1	Metazoa	Metazoa	Echinodermata	Chordata	metal ion binding [GO:0046872]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; granular component [GO:0001652]; platelet dense granule lumen [GO:0031089]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; heparin binding [GO:0008201]; kringle domain binding [GO:0036143]; bone mineralization [GO:0030282]; cellular response to organic substance [GO:0071310]; cellular response to transforming growth factor beta stimulus [GO:0071560]; ossification [GO:0001503]; platelet degranulation [GO:0002576]; positive regulation of plasminogen activation [GO:0010756]		bone mineralization [GO:0030282]; cellular response to organic substance [GO:0071310]; cellular response to transforming growth factor beta stimulus [GO:0071560]; ossification [GO:0001503]; platelet degranulation [GO:0002576]; positive regulation of plasminogen activation [GO:0010756]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; granular component [GO:0001652]; platelet dense granule lumen [GO:0031089]	metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; heparin binding [GO:0008201]; kringle domain binding [GO:0036143]
d3alyb__d1lkua1__1			Crenarchaeota		cytoplasm [GO:0005737]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]				cytoplasm [GO:0005737]		DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	
d3alyb__d4e89a___1			Crenarchaeota		cytoplasm [GO:0005737]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; virion assembly [GO:0019068]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]	host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d3am2a1_d4qx3a3__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]		toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d3am9a4_d1n62c1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3am9b5_d1n61e1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3amca__d3dypb3__1			Thermotogae	Proteobacteria	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellular glucan metabolic process [GO:0006073]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3amda__d1h09a2__1			Thermotogae		extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cellular glucan metabolic process [GO:0006073]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	lysozyme activity [GO:0003796]
d3amda__d4zenb___1			Thermotogae	Firmicutes	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	6-phospho-beta-galactosidase activity [GO:0033920]; carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	6-phospho-beta-galactosidase activity [GO:0033920]
d3amdc__d1yq2f5__1			Thermotogae	Actinobacteria	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3amfb__d2d37a1__1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	FMN binding [GO:0010181]; phenol 2-monooxygenase activity [GO:0018662]	oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]		cofactor binding [GO:0048037]	FMN binding [GO:0010181]; phenol 2-monooxygenase activity [GO:0018662]
d3amfb__d4hmta___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	FMN binding [GO:0010181]; pyridoxamine-phosphate oxidase activity [GO:0004733]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]; pyridoxine biosynthetic process [GO:0008615]	oxidation-reduction process [GO:0055114]	pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]; pyridoxine biosynthetic process [GO:0008615]	cytoplasm [GO:0005737]		cofactor binding [GO:0048037]	FMN binding [GO:0010181]; pyridoxamine-phosphate oxidase activity [GO:0004733]
d3amoa1_d2oqec2__1		Fungi	Actinobacteria	Ascomycota	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	peroxisome [GO:0005777]; aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]; amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]	amine metabolic process [GO:0009308]		peroxisome [GO:0005777]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]	aliphatic-amine oxidase activity [GO:0052595]; aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594]; copper ion binding [GO:0005507]; phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596]; primary amine oxidase activity [GO:0008131]; quinone binding [GO:0048038]; tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593]
d3amza1_d2wp9b1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	xanthine catabolic process [GO:0009115]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d3amza2_d5g5ga2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	periplasmic space [GO:0042597]; carboxylate reductase activity [GO:0047770]; molybdenum ion binding [GO:0030151]; oxidoreductase activity, acting on the aldehyde or oxo group of donors [GO:0016903]; cellular response to DNA damage stimulus [GO:0006974]	xanthine catabolic process [GO:0009115]	cellular response to DNA damage stimulus [GO:0006974]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	periplasmic space [GO:0042597]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	carboxylate reductase activity [GO:0047770]; molybdenum ion binding [GO:0030151]; oxidoreductase activity, acting on the aldehyde or oxo group of donors [GO:0016903]
d3amza4_d1ffuf1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3amza4_d3etrb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d3amzb2_d2w3re2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3an0a__d4deba___1		Metazoa		Chordata		axon hillock [GO:0043203]; centriole [GO:0005814]; centrosome [GO:0005813]; chromosome passenger complex [GO:0032133]; cilium [GO:0005929]; condensed nuclear chromosome, centromeric region [GO:0000780]; cytosol [GO:0005829]; germinal vesicle [GO:0042585]; meiotic spindle [GO:0072687]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle pole [GO:0097431]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle midzone [GO:0051233]; spindle pole centrosome [GO:0031616]; ATP binding [GO:0005524]; histone serine kinase activity [GO:0035174]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; ubiquitin protein ligase binding [GO:0031625]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; anterior/posterior axis specification [GO:0009948]; cell division [GO:0051301]; centrosome localization [GO:0051642]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; G2/M transition of mitotic cell cycle [GO:0000086]; liver regeneration [GO:0097421]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neuron projection extension [GO:1990138]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autophosphorylation [GO:0046777]; protein localization to centrosome [GO:0071539]; protein phosphorylation [GO:0006468]; regulation of centrosome cycle [GO:0046605]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to wounding [GO:0009611]; spindle assembly involved in female meiosis I [GO:0007057]; spindle organization [GO:0007051]; ubiquitin-dependent protein catabolic process [GO:0006511]		anaphase-promoting complex-dependent catabolic process [GO:0031145]; anterior/posterior axis specification [GO:0009948]; cell division [GO:0051301]; centrosome localization [GO:0051642]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; G2/M transition of mitotic cell cycle [GO:0000086]; liver regeneration [GO:0097421]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neuron projection extension [GO:1990138]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autophosphorylation [GO:0046777]; protein localization to centrosome [GO:0071539]; protein phosphorylation [GO:0006468]; regulation of centrosome cycle [GO:0046605]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to wounding [GO:0009611]; spindle assembly involved in female meiosis I [GO:0007057]; spindle organization [GO:0007051]; ubiquitin-dependent protein catabolic process [GO:0006511]		axon hillock [GO:0043203]; centriole [GO:0005814]; centrosome [GO:0005813]; chromosome passenger complex [GO:0032133]; cilium [GO:0005929]; condensed nuclear chromosome, centromeric region [GO:0000780]; cytosol [GO:0005829]; germinal vesicle [GO:0042585]; meiotic spindle [GO:0072687]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle pole [GO:0097431]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle midzone [GO:0051233]; spindle pole centrosome [GO:0031616]		ATP binding [GO:0005524]; histone serine kinase activity [GO:0035174]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625]
d3anxa__d3ieih___1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; spermine synthase activity [GO:0016768]; thermospermine synthase activity [GO:0010487]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; C-terminal protein methylation [GO:0006481]; cellular protein modification process [GO:0006464]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	cellular protein modification process [GO:0006464]; C-terminal protein methylation [GO:0006481]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; spermine synthase activity [GO:0016768]; thermospermine synthase activity [GO:0010487]	protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d3anxb__d2br4c___1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; spermine synthase activity [GO:0016768]; thermospermine synthase activity [GO:0010487]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]		agmatine aminopropyltransferase activity [GO:0043919]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; spermine synthase activity [GO:0016768]; thermospermine synthase activity [GO:0010487]	methyltransferase activity [GO:0008168]
d3aoea1_d1nqtd2__1		Metazoa	Deinococcus-Thermus	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d3aoea1_d2yfga1__1			Deinococcus-Thermus		nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]				nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	
d3aoea2_d1l1fe1__1		Metazoa	Deinococcus-Thermus	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]
d3aoeb1_d1c1db2__1			Deinococcus-Thermus	Actinobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	cellular amino acid metabolic process [GO:0006520]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]			nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d3aofb__d3i3db3__1			Thermotogae	Proteobacteria	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellular glucan metabolic process [GO:0006073]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3aofb__d4ptva___1			Thermotogae	Firmicutes	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	cellular glucan metabolic process [GO:0006073]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3aoga1_d1nr7j2__1		Metazoa	Deinococcus-Thermus	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d3aogb1_d3etga1__1		Metazoa	Deinococcus-Thermus	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d3aogd1_d3etdc1__1		Metazoa	Deinococcus-Thermus	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d3aogd1_d4xgic1__1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]			nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d3aogd2_d3h6kb1__1		Metazoa	Deinococcus-Thermus	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cellular amino acid metabolic process [GO:0006520]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d3aogh1_d1c1xb2__1			Deinococcus-Thermus	Actinobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	cellular amino acid metabolic process [GO:0006520]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]			nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d3aogi1_d2yfhb1__1			Deinococcus-Thermus	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	cellular amino acid metabolic process [GO:0006520]	glutamate biosynthetic process [GO:0006537]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]
d3aogi2_d1i3ma___1		Metazoa	Deinococcus-Thermus	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]	cellular amino acid metabolic process [GO:0006520]	galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]		cytosol [GO:0005829]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; UDP-glucose 4-epimerase activity [GO:0003978]; UDP-N-acetylglucosamine 4-epimerase activity [GO:0003974]
d3aogj1_d3mw9c2__1			Deinococcus-Thermus		nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]				nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	
d3aopa2_d2v4jb2__1			Proteobacteria	Proteobacteria	sulfite reductase complex (NADPH) [GO:0009337]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	sulfur compound metabolic process [GO:0006790]	sulfite reductase complex (NADPH) [GO:0009337]		4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d3aova__d2vmna___1			Euryarchaeota	Firmicutes	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	biosynthetic process [GO:0009058]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]		cytoplasm [GO:0005737]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]
d3aova__d3aepc___1			Euryarchaeota		catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	biosynthetic process [GO:0009058]	transsulfuration [GO:0019346]			catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d3aovc__d3aepb___1			Euryarchaeota		catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	biosynthetic process [GO:0009058]	transsulfuration [GO:0019346]			catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d3aowc__d1ay8a___1			Euryarchaeota	Proteobacteria	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]; aromatic amino acid family biosynthetic process [GO:0009073]	biosynthetic process [GO:0009058]	aromatic amino acid family biosynthetic process [GO:0009073]		cytoplasm [GO:0005737]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; pyridoxal phosphate binding [GO:0030170]
d3ap4a__d1kdka___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; androgen binding [GO:0005497]; steroid binding [GO:0005496]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	androgen binding [GO:0005497]; steroid binding [GO:0005496]
d3ap4b__d5ik5a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	signaling receptor binding [GO:0005102]
d3ap4c__d2du1a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	carbohydrate binding [GO:0030246]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]		carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	carbohydrate binding [GO:0030246]
d3ap4c__d5jozb2__1	Metazoa		Chordata	Bacteroidetes	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	periplasmic space [GO:0042597]; alpha-L-arabinofuranosidase activity [GO:0046556]; symbiotic process benefiting host [GO:0085030]; xyloglucan catabolic process [GO:2000899]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	symbiotic process benefiting host [GO:0085030]; xyloglucan catabolic process [GO:2000899]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	periplasmic space [GO:0042597]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	alpha-L-arabinofuranosidase activity [GO:0046556]
d3ap5a__d3pvng___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d3ap6b__d2e7tc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	carbohydrate binding [GO:0030246]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]		carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	carbohydrate binding [GO:0030246]
d3ap6d__d3w58a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d3ap7a__d5jowa2__1	Metazoa		Chordata	Bacteroidetes	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	periplasmic space [GO:0042597]; alpha-L-arabinofuranosidase activity [GO:0046556]; symbiotic process benefiting host [GO:0085030]; xyloglucan catabolic process [GO:2000899]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	symbiotic process benefiting host [GO:0085030]; xyloglucan catabolic process [GO:2000899]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	periplasmic space [GO:0042597]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	alpha-L-arabinofuranosidase activity [GO:0046556]
d3apbb__d1h1ab___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]		carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	endo-1,4-beta-xylanase activity [GO:0031176]
d3apbb__d3vv1b___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	cytoplasm [GO:0005737]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	cytoplasm [GO:0005737]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d3apga1_d2pbga___1			Euryarchaeota	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	6-phospho-beta-galactosidase activity [GO:0033920]; lactose catabolic process via tagatose-6-phosphate [GO:0019512]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process via tagatose-6-phosphate [GO:0019512]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	6-phospho-beta-galactosidase activity [GO:0033920]
d3apga1_d3dymb3__1			Euryarchaeota	Proteobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3appa__d1sbgb___1	Fungi		Ascomycota		extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3appa__d5p13a___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]			extracellular region [GO:0005576]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d3apyc__d3e2sa2__1			Deinococcus-Thermus	Proteobacteria	cytosol [GO:0005829]; methylenetetrahydrofolate reductase (NAD(P)H) activity [GO:0004489]; nucleotide binding [GO:0000166]; methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]	cytoplasmic side of plasma membrane [GO:0009898]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]; proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]	proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	cytosol [GO:0005829]	cytoplasmic side of plasma membrane [GO:0009898]	methylenetetrahydrofolate reductase (NAD(P)H) activity [GO:0004489]; nucleotide binding [GO:0000166]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]
d3apyg__d2fzna2__1			Deinococcus-Thermus	Proteobacteria	cytosol [GO:0005829]; methylenetetrahydrofolate reductase (NAD(P)H) activity [GO:0004489]; nucleotide binding [GO:0000166]; methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]	cytoplasmic side of plasma membrane [GO:0009898]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]; proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]	proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	cytosol [GO:0005829]	cytoplasmic side of plasma membrane [GO:0009898]	methylenetetrahydrofolate reductase (NAD(P)H) activity [GO:0004489]; nucleotide binding [GO:0000166]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]
d3aq6b__d1hbrc___1		Metazoa	Ciliophora	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell [GO:0005623]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cell [GO:0005623]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3aq7a__d2wy4a___1			Ciliophora	Proteobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]		response to nitrosative stress [GO:0051409]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3aq8b__d3ugya___1		Metazoa	Ciliophora	Mollusca	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3aq9a__d2wtha___1		Metazoa	Ciliophora	Nematoda (roundworms)	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3aq9b__d3bcqc___1		Metazoa	Ciliophora	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3aq9b__d3wcue___1		Metazoa	Ciliophora	Annelida	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3aqib__d2po5b___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d3ar3a4_d5avsa4__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	integral component of membrane [GO:0016021]; ion channel regulator activity [GO:0099106]; ion transport [GO:0006811]; regulation of ion transport [GO:0043269]	calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	ion transport [GO:0006811]; regulation of ion transport [GO:0043269]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]	integral component of membrane [GO:0016021]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]	ion channel regulator activity [GO:0099106]
d3ar4a4_d2zxea1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	integral component of membrane [GO:0016021]; ion channel regulator activity [GO:0099106]; ion transport [GO:0006811]; regulation of ion transport [GO:0043269]	calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	ion transport [GO:0006811]; regulation of ion transport [GO:0043269]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]	integral component of membrane [GO:0016021]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]	ion channel regulator activity [GO:0099106]
d3ar7a4_d3b8ea1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	sodium:potassium-exchanging ATPase complex [GO:0005890]; ion channel regulator activity [GO:0099106]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; potassium ion import across plasma membrane [GO:1990573]; regulation of ion transport [GO:0043269]; sodium ion export across plasma membrane [GO:0036376]; transmembrane transport [GO:0055085]	calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; potassium ion import across plasma membrane [GO:1990573]; regulation of ion transport [GO:0043269]; sodium ion export across plasma membrane [GO:0036376]; transmembrane transport [GO:0055085]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]	sodium:potassium-exchanging ATPase complex [GO:0005890]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]	ion channel regulator activity [GO:0099106]
d3araa__d2qlpd___1	Metazoa		Chordata	Actinobacteria	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d3arbb__d5ldnl1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]; viral capsid [GO:0019028]; structural molecule activity [GO:0005198]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; T=25 icosahedral viral capsid [GO:0039623]; viral capsid [GO:0019028]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d3arbc1_d5k9jl2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3arbc1_d5m76a1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ardc1_d1rhhb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3ardd2_d2exwf1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3area2_d3wjja1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3arfa2_d1c1eh2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3arfa2_d3pxha1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	endosome [GO:0005768]; excitatory synapse [GO:0060076]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; chondroitin sulfate proteoglycan binding [GO:0035373]; heparin binding [GO:0008201]; insulin receptor binding [GO:0005158]; phosphate ion binding [GO:0042301]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; protein-containing complex binding [GO:0044877]; receptor tyrosine kinase binding [GO:0030971]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; cell migration [GO:0016477]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell projection organization [GO:0031345]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of neurotrophin TRK receptor signaling pathway [GO:0051387]; negative regulation of receptor binding [GO:1900121]; nervous system development [GO:0007399]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of apoptotic process [GO:0043065]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of neuron apoptotic process [GO:0043525]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; regulation of neuron projection development [GO:0010975]; regulation of postsynapse organization [GO:0099175]; regulation of synapse structure or activity [GO:0050803]; synaptic membrane adhesion [GO:0099560]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell migration [GO:0016477]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell projection organization [GO:0031345]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of neurotrophin TRK receptor signaling pathway [GO:0051387]; negative regulation of receptor binding [GO:1900121]; nervous system development [GO:0007399]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of apoptotic process [GO:0043065]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of neuron apoptotic process [GO:0043525]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; regulation of neuron projection development [GO:0010975]; regulation of postsynapse organization [GO:0099175]; regulation of synapse structure or activity [GO:0050803]; synaptic membrane adhesion [GO:0099560]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	endosome [GO:0005768]; excitatory synapse [GO:0060076]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cell adhesion molecule binding [GO:0050839]; chondroitin sulfate proteoglycan binding [GO:0035373]; heparin binding [GO:0008201]; insulin receptor binding [GO:0005158]; phosphate ion binding [GO:0042301]; phosphoprotein phosphatase activity [GO:0004721]; protein-containing complex binding [GO:0044877]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d3argb__d5w3me___1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3argd2_d5m6ab2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3arla__d3pt7a___1	Metazoa	Metazoa	Arthropoda	Mollusca	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3arna__d2j4hb___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d3arnb__d1xs6c___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d3arnb__d4xjce___1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d3arnc__d1f7pb___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d3asno2_d1t5kb___1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3asob2_d2y1aa2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3asoo2_d4gp4b2__1	Metazoa		Chordata	Deinococcus-Thermus	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d3asva__d5epob___1				Firmicutes		nucleotide binding [GO:0000166]						nucleotide binding [GO:0000166]
d3asvd__d1z6zc2__1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; aldo-keto reductase (NADP) activity [GO:0004033]; NADP binding [GO:0050661]; sepiapterin reductase activity [GO:0004757]; cofactor metabolic process [GO:0051186]; nitric oxide biosynthetic process [GO:0006809]; oxidation-reduction process [GO:0055114]; regulation of nitric-oxide synthase activity [GO:0050999]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cofactor metabolic process [GO:0051186]; nitric oxide biosynthetic process [GO:0006809]; oxidation-reduction process [GO:0055114]; regulation of nitric-oxide synthase activity [GO:0050999]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		aldo-keto reductase (NADP) activity [GO:0004033]; NADP binding [GO:0050661]; sepiapterin reductase activity [GO:0004757]
d3at1c1_d4fyxa2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d3at1c2_d1q95f1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d3at5a__d1lflq___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3at6a__d3vm9b___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3atga__d1cpna___1			Actinobacteria	Firmicutes	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]	licheninase activity [GO:0042972]
d3atga__d5ca6b___1			Actinobacteria		glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	viral capsid [GO:0019028]; viral life cycle [GO:0019058]	carbohydrate metabolic process [GO:0005975]	viral life cycle [GO:0019058]		viral capsid [GO:0019028]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]	
d3atha__d3fz7c___1			Euryarchaeota	Proteobacteria	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	biosynthetic process [GO:0009058]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]
d3athc__d5dj9b___1			Euryarchaeota	Apicomplexa	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]; L-proline biosynthetic process [GO:0055129]	biosynthetic process [GO:0009058]	L-proline biosynthetic process [GO:0055129]			catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]
d3atma__d1c5y.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d3atna__d2b73a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3atpa__d4z9ja___1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]; protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cell motility [GO:0048870]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; protein homooligomerization [GO:0051260]; receptor clustering [GO:0043113]; regulation of bacterial-type flagellum-dependent cell motility [GO:1902021]; regulation of chemotaxis [GO:0050920]; regulation of protein histidine kinase activity [GO:0032110]; response to amino acid [GO:0043200]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; positive regulation of post-translational protein modification [GO:1901875]; protein homooligomerization [GO:0051260]; regulation of chemotaxis [GO:0050920]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	cell motility [GO:0048870]; cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; protein homooligomerization [GO:0051260]; receptor clustering [GO:0043113]; regulation of bacterial-type flagellum-dependent cell motility [GO:1902021]; regulation of chemotaxis [GO:0050920]; regulation of protein histidine kinase activity [GO:0032110]; response to amino acid [GO:0043200]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	cellular response to amino acid stimulus [GO:0071230]; chemotaxis [GO:0006935]; detection of chemical stimulus [GO:0009593]; positive regulation of post-translational protein modification [GO:1901875]; protein homooligomerization [GO:0051260]; regulation of chemotaxis [GO:0050920]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; methyl accepting chemotaxis protein complex [GO:0098561]	protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]	protein histidine kinase binding [GO:0043424]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]
d3atua1_d5fpna1__1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	blood microparticle [GO:0072562]; CatSper complex [GO:0036128]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; meiotic spindle [GO:0072687]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptonemal complex [GO:0000795]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; glycolipid binding [GO:0051861]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; tau protein binding [GO:0048156]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein phosphorylation [GO:0001934]; protein refolding [GO:0042026]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex disassembly [GO:0070194]; vesicle-mediated transport [GO:0016192]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein phosphorylation [GO:0001934]; protein refolding [GO:0042026]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex disassembly [GO:0070194]; vesicle-mediated transport [GO:0016192]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	blood microparticle [GO:0072562]; CatSper complex [GO:0036128]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; meiotic spindle [GO:0072687]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptonemal complex [GO:0000795]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; glycolipid binding [GO:0051861]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; tau protein binding [GO:0048156]; unfolded protein binding [GO:0051082]
d3atua2_d3o1wa1__1	Metazoa	Fungi	Chordata	Ascomycota	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	cell [GO:0005623]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]
d3atwa__d4d9ra___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3atwb__d3zvfa1__1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3atyb__d4qaib___1		Fungi		Ascomycota	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3atyb__d4rk8a___1		Metazoa		Chordata	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]		cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]
d3atzd__d4ge8a___1		Fungi		Ascomycota	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]					FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]
d3auja__d1e1cb1__1			Proteobacteria	Actinobacteria	propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]					propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d3aujb__d2d0pb___1			Proteobacteria	Proteobacteria	propanediol dehydratase activity [GO:0050215]						propanediol dehydratase activity [GO:0050215]	
d3aujl__d1i9cd___1			Proteobacteria	Firmicutes	propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]; anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]		anaerobic glutamate catabolic process [GO:0019670]; glutamate catabolic process via L-citramalate [GO:0019553]			propanediol dehydratase activity [GO:0050215]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate mutase activity [GO:0050097]
d3aula__d5aekh___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d3auub1_d3oifa___1			Firmicutes	Firmicutes	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; identical protein binding [GO:0042802]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; cellular response to cold [GO:0070417]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]		cellular response to cold [GO:0070417]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]			glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; identical protein binding [GO:0042802]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]
d3auva2_d6b9jl2__1						integral component of membrane [GO:0016021]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]				integral component of membrane [GO:0016021]		carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3auvb2_d4yhol1__1												
d3auvc1_d1gpoi1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3auvc1_d4kaql1__1												
d3auvd1_d4f9lc1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor binding [GO:0005102]; activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; cytokine secretion [GO:0050663]; interferon-gamma secretion [GO:0072643]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; cytokine secretion [GO:0050663]; interferon-gamma secretion [GO:0072643]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		signaling receptor binding [GO:0005102]
d3auve1_d3mrrb1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3auve1_d5lgja1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3av1a__d5gt3h___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3av7a__d1lc7a___1			Euryarchaeota	Proteobacteria	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	pyridoxal phosphate binding [GO:0030170]; threonine-phosphate decarboxylase activity [GO:0048472]; cobalamin biosynthetic process [GO:0009236]	biosynthetic process [GO:0009058]	cobalamin biosynthetic process [GO:0009236]			catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]	pyridoxal phosphate binding [GO:0030170]; threonine-phosphate decarboxylase activity [GO:0048472]
d3av8a__d1e9ma___1			Cyanobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3av8a__d3vrbb1__1		Metazoa	Cyanobacteria	Nematoda (roundworms)	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d3av8b__d1frrb___1		Viridiplantae	Cyanobacteria	Streptophyta	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	chloroplast [GO:0009507]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]				chloroplast [GO:0009507]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3av8c__d2wu5f1__1			Cyanobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]		aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d3avea1_d3pwne1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3aveb1_d5m7qa1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3aveb2_d1bvkd___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3avza__d4fu7a___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]
d3aw0a__d1f5la___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]
d3aw7a__d1lz1a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3awdc__d3om9b1__1			Proteobacteria	Apicomplexa	oxidoreductase activity [GO:0016491]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]			oxidoreductase activity [GO:0016491]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d3awdd__d1guza1__1			Proteobacteria	Chlorobi	oxidoreductase activity [GO:0016491]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]			oxidoreductase activity [GO:0016491]	L-malate dehydrogenase activity [GO:0030060]
d3awja2_d5bnsa2__1	Viridiplantae		Streptophyta	Proteobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		cytosol [GO:0005829]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d3awqa__d4uhlh1__1		Metazoa	Proteobacteria	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]; cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]
d3awwa1_d1hcyf2__1		Metazoa	Actinobacteria	Arthropoda	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; oxygen carrier activity [GO:0005344]				extracellular space [GO:0005615]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; oxygen carrier activity [GO:0005344]
d3awya1_d3nm8a___1			Actinobacteria	Firmicutes	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d3ax0a1_d5i3ba___1			Actinobacteria	Firmicutes	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d3ax7a1_d3p1mf1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	xanthine catabolic process [GO:0009115]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]
d3ax7a3_d1n5xb4__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d3ax7a5_d1diib2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]
d3ax7a6_d1rm6a1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]
d3ax7b1_d1puta___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3ax7b2_d3hrdh2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	FAD binding [GO:0071949]; nicotinate dehydrogenase activity [GO:0050138]; cofactor catabolic process [GO:0051187]	xanthine catabolic process [GO:0009115]	cofactor catabolic process [GO:0051187]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	FAD binding [GO:0071949]; nicotinate dehydrogenase activity [GO:0050138]
d3ax9a1_d1n60a2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3ax9a1_d3huia1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3ax9a3_d2w3ra4__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3ax9a6_d1t3qe1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	oxidoreductase activity [GO:0016491]
d3axca2_d4gocb1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]; cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]	polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]
d3axda__d1jxnb___1		Viridiplantae	Fibrobacteres	Streptophyta	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]				licheninase activity [GO:0042972]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3axlb1_d4hjjl3__1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]		activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]		cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d3axlb2_d5u4mb___1		Viridiplantae		Streptophyta		endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3axlh1_d4ma1f2__1												
d3axlh2_d2cdga1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3axmt__d1uzhi___1	Viridiplantae	Viridiplantae	Streptophyta	Chlorophyta	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]; magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	chloroplast [GO:0009507]	chloroplast [GO:0009507]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3axyi__d1ib1c___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; phosphatidylethanolamine binding [GO:0008429]; cell differentiation [GO:0030154]; flower development [GO:0009908]; inflorescence development [GO:0010229]; regulation of flower development [GO:0009909]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; short-day photoperiodism [GO:0048572]; short-day photoperiodism, flowering [GO:0048575]	perinuclear region of cytoplasm [GO:0048471]; aralkylamine N-acetyltransferase activity [GO:0004059]; cellular response to cAMP [GO:0071320]; circadian rhythm [GO:0007623]; melatonin biosynthetic process [GO:0030187]; N-terminal protein amino acid acetylation [GO:0006474]	cell differentiation [GO:0030154]; flower development [GO:0009908]; inflorescence development [GO:0010229]; regulation of flower development [GO:0009909]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; short-day photoperiodism [GO:0048572]; short-day photoperiodism, flowering [GO:0048575]	cellular response to cAMP [GO:0071320]; circadian rhythm [GO:0007623]; melatonin biosynthetic process [GO:0030187]; N-terminal protein amino acid acetylation [GO:0006474]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	perinuclear region of cytoplasm [GO:0048471]	phosphatidylethanolamine binding [GO:0008429]	aralkylamine N-acetyltransferase activity [GO:0004059]
d3ay2a__d3abmb2__1		Metazoa	Proteobacteria	Chordata	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]		ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d3ay4a1_d5do2l1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	IgG binding [GO:0019864]	
d3ay4b2_d1ohqb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	IgG binding [GO:0019864]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ay6a1_d1jkja1__1			Firmicutes	Proteobacteria	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; identical protein binding [GO:0042802]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]		nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; identical protein binding [GO:0042802]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d3ay6b1_d2zyab1__1			Firmicutes	Proteobacteria	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; identical protein binding [GO:0042802]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; protein homodimerization activity [GO:0042803]; D-gluconate catabolic process [GO:0046177]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]		D-gluconate catabolic process [GO:0046177]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]		cytosol [GO:0005829]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; identical protein binding [GO:0042802]	identical protein binding [GO:0042802]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; protein homodimerization activity [GO:0042803]
d3ay7a1_d1v9lb1__1			Firmicutes	Crenarchaeota	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]			glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d3ay8a1_d1zyec1__1	Metazoa	Metazoa	Arthropoda	Chordata	transferase activity [GO:0016740]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	transferase activity [GO:0016740]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d3ay9a2_d1nbwc3__1	Metazoa		Chordata	Proteobacteria	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	ATP binding [GO:0005524]; glycerol dehydratase activity [GO:0046405]; metal ion binding [GO:0046872]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]		aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]	ATP binding [GO:0005524]; glycerol dehydratase activity [GO:0046405]; metal ion binding [GO:0046872]
d3ay9a2_d4rwta2__1	Metazoa	Metazoa	Chordata	Arthropoda	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]	ATP binding [GO:0005524]
d3ayca1_d1v6jc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]		carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3aywc__d1p3id___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3az4a__d2bqja___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3az6a__d4ml7c___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3az8a__d5hwfa___1			Apicomplexa	Firmicutes	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	thiolester hydrolase activity [GO:0016790]	fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]	thiolester hydrolase activity [GO:0016790]
d3az8k__d2glmc___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3az8k__d4qd9c___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]	fatty acid biosynthetic process [GO:0006633]			cytosol [GO:0005829]	hydro-lyase activity [GO:0016836]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]
d3az8m__d5eo2c1__1			Apicomplexa	Firmicutes	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]	
d3az8n__d3d04b___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3az8n__d4qd9d___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]	fatty acid biosynthetic process [GO:0006633]			cytosol [GO:0005829]	hydro-lyase activity [GO:0016836]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]
d3az8r__d3r3fb___1			Apicomplexa	Actinobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]
d3az8v__d2gllc___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3az8x__d2glvg___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3az8x__d4fq9j___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]	fatty acid biosynthetic process [GO:0006633]	unsaturated fatty acid biosynthetic process [GO:0006636]		cytoplasm [GO:0005737]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]
d3az9g__d5hz4c___1			Apicomplexa	Firmicutes	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	thiolester hydrolase activity [GO:0016790]	fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]	thiolester hydrolase activity [GO:0016790]
d3az9h__d3dp2c___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3az9i__d4zrfa___1			Apicomplexa	Firmicutes	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	acyl-CoA hydrolase activity [GO:0047617]	fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]	acyl-CoA hydrolase activity [GO:0047617]
d3az9j__d4k4bg___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]; menaquinone biosynthetic process [GO:0009234]	fatty acid biosynthetic process [GO:0006633]	menaquinone biosynthetic process [GO:0009234]		cytosol [GO:0005829]	hydro-lyase activity [GO:0016836]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]
d3az9m__d2fuja1__1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	acyl-CoA hydrolase activity [GO:0047617]	fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]	acyl-CoA hydrolase activity [GO:0047617]
d3az9m__d3dozb___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3az9r__d1c8ua1__1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; acyl-CoA hydrolase activity [GO:0047617]; identical protein binding [GO:0042802]; acyl-CoA metabolic process [GO:0006637]; fatty acid catabolic process [GO:0009062]	fatty acid biosynthetic process [GO:0006633]	acyl-CoA metabolic process [GO:0006637]; fatty acid catabolic process [GO:0009062]		cytosol [GO:0005829]	hydro-lyase activity [GO:0016836]	acyl-CoA hydrolase activity [GO:0047617]; identical protein binding [GO:0042802]
d3az9r__d3doyd___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3az9t__d1vi8b1__1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]; menaquinone biosynthetic process [GO:0009234]	fatty acid biosynthetic process [GO:0006633]	menaquinone biosynthetic process [GO:0009234]		cytosol [GO:0005829]	hydro-lyase activity [GO:0016836]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]
d3azac__d5buxb___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3azad__d1z54d___1			Apicomplexa	Deinococcus-Thermus	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	hydrolase activity [GO:0016787]	fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]	hydrolase activity [GO:0016787]
d3azad__d3doze___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3azaj__d3cf8f___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3azal__d1wn3d___1			Apicomplexa	Deinococcus-Thermus	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	thiolester hydrolase activity [GO:0016790]	fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]	thiolester hydrolase activity [GO:0016790]
d3azao__d4i83d___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3azar__d5byub___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]	
d3azau__d1mkbb___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]
d3azba__d2gllb___1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	hydro-lyase activity [GO:0016836]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3azbc__d2egic___1			Apicomplexa	Aquificae	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	acyl-CoA hydrolase activity [GO:0047617]	fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]	acyl-CoA hydrolase activity [GO:0047617]
d3azbf__d2qq2k___1		Metazoa	Apicomplexa	Chordata	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290]; protein homodimerization activity [GO:0042803]; acyl-CoA metabolic process [GO:0006637]; coenzyme A biosynthetic process [GO:0015937]; long-chain fatty-acyl-CoA catabolic process [GO:0036116]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; palmitic acid biosynthetic process [GO:1900535]	fatty acid biosynthetic process [GO:0006633]	acyl-CoA metabolic process [GO:0006637]; coenzyme A biosynthetic process [GO:0015937]; long-chain fatty-acyl-CoA catabolic process [GO:0036116]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; palmitic acid biosynthetic process [GO:1900535]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	hydro-lyase activity [GO:0016836]	acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290]; protein homodimerization activity [GO:0042803]
d3azbl__d1vi8c1__1			Apicomplexa	Proteobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]; menaquinone biosynthetic process [GO:0009234]	fatty acid biosynthetic process [GO:0006633]	menaquinone biosynthetic process [GO:0009234]		cytosol [GO:0005829]	hydro-lyase activity [GO:0016836]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]
d3azbs__d1q4ub___1			Apicomplexa	Actinobacteria	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]
d3azbu__d1wm6g___1			Apicomplexa	Deinococcus-Thermus	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	thiolester hydrolase activity [GO:0016790]	fatty acid biosynthetic process [GO:0006633]				hydro-lyase activity [GO:0016836]	thiolester hydrolase activity [GO:0016790]
d3azca1_d2de7c1__1			Cyanobacteria	Proteobacteria	integral component of membrane [GO:0016021]; thylakoid membrane [GO:0042651]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity [GO:0045158]; metal ion binding [GO:0046872]; plastoquinol--plastocyanin reductase activity [GO:0009496]; ubiquinol-cytochrome-c reductase activity [GO:0008121]; photosynthesis [GO:0015979]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]	photosynthesis [GO:0015979]	carbazole catabolic process [GO:0046232]	integral component of membrane [GO:0016021]; thylakoid membrane [GO:0042651]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity [GO:0045158]; metal ion binding [GO:0046872]; plastoquinol--plastocyanin reductase activity [GO:0009496]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]
d3azeb__d2bymb___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	CHRAC [GO:0008623]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]; nucleosome mobilization [GO:0042766]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleosome mobilization [GO:0042766]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	CHRAC [GO:0008623]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]
d3azga__d5b2jc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3azge__d1p3ob___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3azgf__d4jjnc___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	CENP-A containing nucleosome [GO:0043505]; nuclear nucleosome [GO:0000788]; nucleus [GO:0005634]; replication fork protection complex [GO:0031298]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin assembly or disassembly [GO:0006333]; global genome nucleotide-excision repair [GO:0070911]; rRNA transcription [GO:0009303]; sexual sporulation resulting in formation of a cellular spore [GO:0043935]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromatin assembly or disassembly [GO:0006333]; global genome nucleotide-excision repair [GO:0070911]; rRNA transcription [GO:0009303]; sexual sporulation resulting in formation of a cellular spore [GO:0043935]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	CENP-A containing nucleosome [GO:0043505]; nuclear nucleosome [GO:0000788]; nucleus [GO:0005634]; replication fork protection complex [GO:0031298]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3azif__d5mlua___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3azjb__d3mnna___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3azma__d3azgc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3azmb__d5omxc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3azme__d5gt3g___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3azmf__d3mgpa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3aznb__d1p3ic___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3aznf__d1n1ja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	CCAAT-binding factor complex [GO:0016602]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; protein folding [GO:0006457]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	protein folding [GO:0006457]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	CCAAT-binding factor complex [GO:0016602]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]
d3azng__d5omxd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3azsa__d3i3dc3__1			Thermotogae	Proteobacteria	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellular glucan metabolic process [GO:0006073]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3azsb__d1yq2c5__1			Thermotogae	Actinobacteria	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3azsb__d4qlka___1		Viridiplantae	Thermotogae	Streptophyta	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d3aztc__d1r8la___1			Thermotogae	Firmicutes	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	cellular glucan metabolic process [GO:0006073]	metabolic process [GO:0008152]	extracellular region [GO:0005576]		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]
d3azua__d2ih8b3__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	oxidation-reduction process [GO:0055114]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3azub__d1kbvf1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	cell outer membrane [GO:0009279]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3azuc__d2plta___1		Viridiplantae	Proteobacteria	Chlorophyta	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3azuc__d3t6wc3__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3azud__d1kyad3__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3azud__d2tsac___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3azya__d4hl0b2__1		Metazoa	Thermotogae	Nematoda (roundworms)	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]	carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d3azyd__d1n3ob___1		Viridiplantae	Thermotogae	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3azzb__d1macb___1			Thermotogae	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	licheninase activity [GO:0042972]
d3azzd__d2vy0b___1			Thermotogae	Euryarchaeota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3azzd__d4ctea___1			Thermotogae	Bacteroidetes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]
d3b00b__d3uv9a1__1		Metazoa	Thermotogae	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]; identical protein binding [GO:0042802]; signaling pattern recognition receptor activity [GO:0008329]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipopolysaccharide-mediated signaling pathway [GO:0031664]; regulation of protein localization [GO:0032880]	carbohydrate metabolic process [GO:0005975]	activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipopolysaccharide-mediated signaling pathway [GO:0031664]; regulation of protein localization [GO:0032880]		cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; signaling pattern recognition receptor activity [GO:0008329]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d3b00c__d5ewsl___1		Metazoa	Thermotogae	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d3b01b__d1xnba___1			Thermotogae	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d3b01d__d2hyka___1			Thermotogae	Actinobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3b08a2_d4wipb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	aggresome [GO:0016235]; apical part of cell [GO:0045177]; clathrin-coated endocytic vesicle [GO:0045334]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein binding, bridging [GO:0030674]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; Rac GTPase binding [GO:0048365]; beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cellular protein localization [GO:0034613]; cochlea morphogenesis [GO:0090103]; convergent extension involved in neural plate elongation [GO:0022007]; heart development [GO:0007507]; hippo signaling [GO:0035329]; membrane organization [GO:0061024]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neural tube closure [GO:0001843]; non-canonical Wnt signaling pathway [GO:0035567]; outflow tract morphogenesis [GO:0003151]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of transcription, DNA-templated [GO:0045893]; segment specification [GO:0007379]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cellular protein localization [GO:0034613]; cochlea morphogenesis [GO:0090103]; convergent extension involved in neural plate elongation [GO:0022007]; heart development [GO:0007507]; hippo signaling [GO:0035329]; membrane organization [GO:0061024]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neural tube closure [GO:0001843]; non-canonical Wnt signaling pathway [GO:0035567]; outflow tract morphogenesis [GO:0003151]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of transcription, DNA-templated [GO:0045893]; segment specification [GO:0007379]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	aggresome [GO:0016235]; apical part of cell [GO:0045177]; clathrin-coated endocytic vesicle [GO:0045334]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein binding, bridging [GO:0030674]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; Rac GTPase binding [GO:0048365]
d3b08g1_d4x57d___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	plasma membrane [GO:0005886]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	plasma membrane [GO:0005886]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	
d3b08j1_d2bwfb___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; nucleus [GO:0005634]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein binding, bridging [GO:0030674]; protein localization to vacuole [GO:0072665]; spindle pole body duplication [GO:0030474]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	protein localization to vacuole [GO:0072665]; spindle pole body duplication [GO:0030474]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytosol [GO:0005829]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	polyubiquitin modification-dependent protein binding [GO:0031593]; protein binding, bridging [GO:0030674]
d3b08j2_d2jvca1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]		protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	
d3b0ad1_d5chfa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3b0ad2_d5jg6b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3b0ha3_d3mm8a1__1	Viridiplantae		Streptophyta	Euryarchaeota	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]		sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d3b0hb3_d3mm5e1__1	Viridiplantae		Streptophyta	Euryarchaeota	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]		sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d3b0ia1_d2ntga___1	Metazoa		Chordata		extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]	host cell cytoplasm [GO:0030430]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]	lysozyme activity [GO:0003796]
d3b0ja1_d3b0ha3__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3b0la3_d3mm6e1__1	Viridiplantae		Streptophyta	Euryarchaeota	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]		sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d3b0la4_d4g38a4__1	Viridiplantae		Streptophyta	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfite reductase complex (NADPH) [GO:0009337]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]		cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]		sulfite reductase complex (NADPH) [GO:0009337]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]
d3b0ma1_d1zj9b2__1	Viridiplantae		Streptophyta	Actinobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]		cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]		cell wall [GO:0005618]; cytosol [GO:0005829]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]
d3b0ma2_d3vlxa2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3b0ma3_d3mm7b1__1	Viridiplantae		Streptophyta	Euryarchaeota	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]		sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d3b0na1_d3mmab1__1	Viridiplantae		Streptophyta	Euryarchaeota	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]		sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d3b0na4_d3b0ga4__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3b0ob1_d7lyza___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; signal transduction [GO:0007165]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3b0wb__d1fm6x___1	Metazoa	Metazoa	Chordata	Chordata	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]	androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]
d3b12a__d1a8ua___1			Proteobacteria	Actinobacteria	haloacetate dehalogenase activity [GO:0018785]	chloride peroxidase activity [GO:0016691]					haloacetate dehalogenase activity [GO:0018785]	chloride peroxidase activity [GO:0016691]
d3b12b__d3i6za___1		Metazoa	Proteobacteria	Chordata	haloacetate dehalogenase activity [GO:0018785]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]		acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	haloacetate dehalogenase activity [GO:0018785]	acetylcholinesterase activity [GO:0003990]
d3b1ca__d1amqa___1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	biosynthetic process [GO:0009058]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d3b1cb__d1m0pa___1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	biosynthetic process [GO:0009058]				lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]	2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d3b1cd__d4b98a___1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]; beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	biosynthetic process [GO:0009058]	beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]			lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]
d3b1ec__d1n2ta1__1			Firmicutes	Cyanobacteria	lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	lyase activity [GO:0016829]	biosynthetic process [GO:0009058]				lyase activity [GO:0016829]; pyridoxal phosphate binding [GO:0030170]	lyase activity [GO:0016829]
d3b1oa1_d2i6ad___1		Metazoa	Proteobacteria	Chordata	kinase activity [GO:0016301]; nucleotide binding [GO:0000166]; phosphotransferase activity, alcohol group as acceptor [GO:0016773]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; AMP salvage [GO:0044209]; dATP biosynthetic process [GO:0006175]; purine ribonucleoside salvage [GO:0006166]; purine-containing compound salvage [GO:0043101]; ribonucleoside monophosphate biosynthetic process [GO:0009156]		AMP salvage [GO:0044209]; dATP biosynthetic process [GO:0006175]; purine-containing compound salvage [GO:0043101]; purine ribonucleoside salvage [GO:0006166]; ribonucleoside monophosphate biosynthetic process [GO:0009156]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	kinase activity [GO:0016301]; nucleotide binding [GO:0000166]; phosphotransferase activity, alcohol group as acceptor [GO:0016773]	adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3b1ra__d1gqtd___1			Proteobacteria	Proteobacteria	kinase activity [GO:0016301]; nucleotide binding [GO:0000166]; phosphotransferase activity, alcohol group as acceptor [GO:0016773]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]		D-ribose catabolic process [GO:0019303]		cytosol [GO:0005829]	kinase activity [GO:0016301]; nucleotide binding [GO:0000166]; phosphotransferase activity, alcohol group as acceptor [GO:0016773]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d3b1rc__d5c3za1__1		Metazoa	Proteobacteria	Chordata	kinase activity [GO:0016301]; nucleotide binding [GO:0000166]; phosphotransferase activity, alcohol group as acceptor [GO:0016773]	cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]		D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]		cytosol [GO:0005829]; nucleus [GO:0005634]	kinase activity [GO:0016301]; nucleotide binding [GO:0000166]; phosphotransferase activity, alcohol group as acceptor [GO:0016773]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d3b25a__d1z5bb3__1	Metazoa		Chordata	Crenarchaeota	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]
d3b27a__d2yeia___1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3b2fa__d3w5uf___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; electron transport chain [GO:0022900]; response to light stimulus [GO:0009416]	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	electron transport chain [GO:0022900]; response to light stimulus [GO:0009416]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]	chloroplast thylakoid membrane protein complex [GO:0098807]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d3b2ha1_d3ppta1__1	Metazoa	Metazoa	Chordata	Mollusca	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	cytoplasm [GO:0005737]; membrane [GO:0016020]; lipid binding [GO:0008289]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]		apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; membrane [GO:0016020]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]	lipid binding [GO:0008289]
d3b2ja1_d2ansb___1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d3b2ja1_d4wfua___1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]; small molecule binding [GO:0036094]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]		apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]	small molecule binding [GO:0036094]
d3b2ka1_d4a60a1__1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; lipid binding [GO:0008289]; acrosome assembly [GO:0001675]; triglyceride catabolic process [GO:0019433]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	acrosome assembly [GO:0001675]; triglyceride catabolic process [GO:0019433]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]	lipid binding [GO:0008289]
d3b2ka1_d5hz8a1__1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d3b2qa3_d1cowd1__1		Metazoa	Euryarchaeota	Chordata	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3b2qb3_d2v7qf3__1		Metazoa	Euryarchaeota	Chordata	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3b2ub1_d2wqud1__1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	pathogenesis [GO:0009405]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	heparin binding [GO:0008201]; lipid binding [GO:0008289]
d3b2uc1_d2mhad___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3b2ud2_d3ks0l2__1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]
d3b2uf1_d4gmtm1__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	
d3b2ug2_d1uz6f1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3b2ui1_d3h3ba1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]
d3b2uj1_d1mrdl1__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	
d3b2ul1_d1f4wl2__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	
d3b2ul2_d1nfdb1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3b2um1_d4po4a___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	integral component of membrane [GO:0016021]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	
d3b2uo2_d5o04d1__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	
d3b2up1_d2omxa3__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3b2ur1_d2gfbh1__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	
d3b2us1_d2r9ub1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	
d3b2uu1_d2ny4c1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3b2uu2_d1gsma2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; integrin binding involved in cell-matrix adhesion [GO:0098640]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	integrin binding involved in cell-matrix adhesion [GO:0098640]
d3b2uw1_d6emjl2__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	
d3b35a__d2pj9a___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d3b36a1_d1gged1__1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3b3ea__d5jgwa___1		Viridiplantae		Streptophyta		nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]						nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3b3eb__d4prra___1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]		C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d3b3he__d4dz0a___1		Metazoa		Chordata		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3b3hf__d4n83b___1				Firmicutes		ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		ribonucleoside-diphosphate reductase complex [GO:0005971]		metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3b3hg__d2xjmd___1				Firmicutes		cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d3b3hg__d2yjjh___1				Actinobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		ferric iron binding [GO:0008199]
d3b3hh__d3mpsd1__1				Euryarchaeota		iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]						iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3b3hi__d1mxra___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3b3hj__d2z6mh___1		Metazoa		Chordata		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3b3hk__d1bcfl___1				Proteobacteria		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3b3hk__d3uoig___1				Actinobacteria		cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]		response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3b3ia1_d4xp1l1__1	Metazoa	Metazoa	Chordata	Arthropoda	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]; adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of plasma membrane [GO:0005887]; neuronal cell body membrane [GO:0032809]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]
d3b3ib2_d1igch1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3b3ta__d4nfra___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; nucleus [GO:0005634]; aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]		aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	extracellular region [GO:0005576]	cytosol [GO:0005829]; nucleus [GO:0005634]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3b3wa__d1ee3p___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d3b4tb2_d2c38e2__1			Actinobacteria	Crenarchaeota	plasma membrane [GO:0005886]; 3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	rRNA catabolic process [GO:0016075]	plasma membrane [GO:0005886]	cytoplasmic exosome (RNase complex) [GO:0000177]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	3'-5'-exoribonuclease activity [GO:0000175]
d3b4tc2_d4ba1b2__1			Actinobacteria	Crenarchaeota	plasma membrane [GO:0005886]; 3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475]	plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]	poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d3b4ua__d1f5zb___1			Proteobacteria	Proteobacteria	lyase activity [GO:0016829]	cytosol [GO:0005829]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]		carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]		cytosol [GO:0005829]	lyase activity [GO:0016829]	N-acetylneuraminate lyase activity [GO:0008747]
d3b4ua__d3e96a___1			Proteobacteria	Firmicutes	lyase activity [GO:0016829]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]					lyase activity [GO:0016829]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3b4ub__d4s1fl1__1			Proteobacteria	Proteobacteria	lyase activity [GO:0016829]	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]		fructose metabolic process [GO:0006000]		cytoplasm [GO:0005737]	lyase activity [GO:0016829]	fructose 6-phosphate aldolase activity [GO:0097023]
d3b4ub__d5dbta___1			Proteobacteria	Firmicutes	lyase activity [GO:0016829]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]		carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]		cytoplasm [GO:0005737]	lyase activity [GO:0016829]	deoxyribose-phosphate aldolase activity [GO:0004139]
d3b4wa__d2opxa___1			Actinobacteria	Proteobacteria	plasma membrane [GO:0005886]; ADP binding [GO:0043531]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	cytosol [GO:0005829]; glycolaldehyde dehydrogenase activity [GO:0050569]; identical protein binding [GO:0042802]; lactaldehyde dehydrogenase activity [GO:0008911]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; L-fucose catabolic process [GO:0042355]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]		L-fucose catabolic process [GO:0042355]; protein homotetramerization [GO:0051289]; rhamnose catabolic process [GO:0019301]	plasma membrane [GO:0005886]	cytosol [GO:0005829]	ADP binding [GO:0043531]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	glycolaldehyde dehydrogenase activity [GO:0050569]; identical protein binding [GO:0042802]; lactaldehyde dehydrogenase activity [GO:0008911]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]
d3b5gb__d1yylh2__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d3b5hc2_d1ev2g1__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3b5hd1_d1evtd1__1	Metazoa	Metazoa	Chordata	Chordata	acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3b5zb1_d1vpla___1			Proteobacteria	Thermotogae	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]	ATP binding [GO:0005524]; ATPase activity [GO:0016887]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		ATPase activity [GO:0016887]; ATPase-coupled lipid transmembrane transporter activity [GO:0034040]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; xenobiotic transmembrane transporter activity [GO:0042910]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]
d3b65a__d1g5yb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; androgen binding [GO:0005497]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; nuclear receptor activity [GO:0004879]; POU domain binding [GO:0070974]; protein dimerization activity [GO:0046983]; RNA polymerase II general transcription initiation factor binding [GO:0001091]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]; activation of prostate induction by androgen receptor signaling pathway [GO:0060520]; androgen receptor signaling pathway [GO:0030521]; animal organ formation [GO:0048645]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to steroid hormone stimulus [GO:0071383]; cellular response to testosterone stimulus [GO:0071394]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; epithelial cell morphogenesis [GO:0003382]; in utero embryonic development [GO:0001701]; intracellular receptor signaling pathway [GO:0030522]; lateral sprouting involved in mammary gland duct morphogenesis [GO:0060599]; Leydig cell differentiation [GO:0033327]; male genitalia morphogenesis [GO:0048808]; male somatic sex determination [GO:0019102]; mammary gland alveolus development [GO:0060749]; morphogenesis of an epithelial fold [GO:0060571]; multicellular organism growth [GO:0035264]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of integrin biosynthetic process [GO:0045720]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of integrin biosynthetic process [GO:0045726]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription, DNA-templated [GO:0045893]; prostate gland development [GO:0030850]; prostate gland epithelium morphogenesis [GO:0060740]; prostate gland growth [GO:0060736]; protein deubiquitination [GO:0016579]; regulation of developmental growth [GO:0048638]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of systemic arterial blood pressure [GO:0003073]; seminiferous tubule development [GO:0072520]; sex differentiation [GO:0007548]; signal transduction [GO:0007165]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]	mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]; chromatin DNA binding [GO:0031490]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; nuclear receptor activity [GO:0004879]; nuclear receptor binding [GO:0016922]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; retinoic acid binding [GO:0001972]; retinoic acid-responsive element binding [GO:0044323]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription coactivator activity [GO:0003713]; vitamin D receptor binding [GO:0042809]; zinc ion binding [GO:0008270]; anatomical structure development [GO:0048856]; bile acid and bile salt transport [GO:0015721]; camera-type eye development [GO:0043010]; cardiac muscle cell proliferation [GO:0060038]; cell differentiation [GO:0030154]; cholesterol metabolic process [GO:0008203]; embryo implantation [GO:0007566]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; modulation by virus of host morphology or physiology [GO:0019048]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ventricular cardiac muscle cell differentiation [GO:0055012]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; vitamin metabolic process [GO:0006766]	activation of prostate induction by androgen receptor signaling pathway [GO:0060520]; androgen receptor signaling pathway [GO:0030521]; animal organ formation [GO:0048645]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to steroid hormone stimulus [GO:0071383]; cellular response to testosterone stimulus [GO:0071394]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; epithelial cell morphogenesis [GO:0003382]; intracellular receptor signaling pathway [GO:0030522]; in utero embryonic development [GO:0001701]; lateral sprouting involved in mammary gland duct morphogenesis [GO:0060599]; Leydig cell differentiation [GO:0033327]; male genitalia morphogenesis [GO:0048808]; male somatic sex determination [GO:0019102]; mammary gland alveolus development [GO:0060749]; morphogenesis of an epithelial fold [GO:0060571]; multicellular organism growth [GO:0035264]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of integrin biosynthetic process [GO:0045720]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of integrin biosynthetic process [GO:0045726]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; prostate gland development [GO:0030850]; prostate gland epithelium morphogenesis [GO:0060740]; prostate gland growth [GO:0060736]; protein deubiquitination [GO:0016579]; regulation of developmental growth [GO:0048638]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of systemic arterial blood pressure [GO:0003073]; seminiferous tubule development [GO:0072520]; sex differentiation [GO:0007548]; signal transduction [GO:0007165]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription, DNA-templated [GO:0006351]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anatomical structure development [GO:0048856]; bile acid and bile salt transport [GO:0015721]; camera-type eye development [GO:0043010]; cardiac muscle cell proliferation [GO:0060038]; cell differentiation [GO:0030154]; cholesterol metabolic process [GO:0008203]; embryo implantation [GO:0007566]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; modulation by virus of host morphology or physiology [GO:0019048]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ventricular cardiac muscle cell differentiation [GO:0055012]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; vitamin metabolic process [GO:0006766]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]	androgen binding [GO:0005497]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; nuclear receptor activity [GO:0004879]; POU domain binding [GO:0070974]; protein dimerization activity [GO:0046983]; RNA polymerase II general transcription initiation factor binding [GO:0001091]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]	chromatin DNA binding [GO:0031490]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; nuclear receptor activity [GO:0004879]; nuclear receptor binding [GO:0016922]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; retinoic acid binding [GO:0001972]; retinoic acid-responsive element binding [GO:0044323]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription coactivator activity [GO:0003713]; vitamin D receptor binding [GO:0042809]; zinc ion binding [GO:0008270]
d3b69a2_d2htyg___1				Negarnaviricota	integral component of membrane [GO:0016021]; exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	integral component of membrane [GO:0016021]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-sialidase activity [GO:0004308]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3b6fd1_d2f8nk1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3b6ib__d4u7ga___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d3b6ja__d4y9ra1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d3b6ja__d4zvkb___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d3b6qa__d3zsfd___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d3b6ra2_d4lnfj2__1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d3b6rb1_d1n16a3__1	Metazoa		Chordata		cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]		cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]		cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	
d3b6rb2_d1htol2__1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3b6sb2_d2bckd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3b6sb2_d4lstl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3b6ta__d4exlb___1	Metazoa		Chordata	Firmicutes	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	plasma membrane [GO:0005886]; phosphate ion binding [GO:0042301]; phosphate ion transport [GO:0006817]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	phosphate ion transport [GO:0006817]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	plasma membrane [GO:0005886]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	phosphate ion binding [GO:0042301]
d3b6wc__d3m3kc___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3b6xa1_d4f7fb___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]	courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]	dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]
d3b6xb1_d2wc6a___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	odorant binding [GO:0005549]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	extracellular region [GO:0005576]		dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]	odorant binding [GO:0005549]
d3b6ya1_d4jbja1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; double-stranded DNA binding [GO:0003690]; activation of innate immune response [GO:0002218]; cellular response to interferon-beta [GO:0035458]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of innate immune response [GO:0045824]; positive regulation of interleukin-1 beta production [GO:0032731]; response to bacterium [GO:0009617]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of innate immune response [GO:0002218]; cellular response to interferon-beta [GO:0035458]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of innate immune response [GO:0045824]; positive regulation of interleukin-1 beta production [GO:0032731]; response to bacterium [GO:0009617]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	double-stranded DNA binding [GO:0003690]
d3b71c__d3gm1a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	apical dendrite [GO:0097440]; cell [GO:0005623]; cell body [GO:0044297]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase binding [GO:0043423]; ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; NMDA glutamate receptor activity [GO:0004972]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein C-terminus binding [GO:0008022]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; ubiquitin protein ligase binding [GO:0031625]; activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-containing complex assembly [GO:0065003]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of NMDA receptor activity [GO:2000310]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of synaptic plasticity [GO:0048167]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; protein-containing complex assembly [GO:0065003]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of NMDA receptor activity [GO:2000310]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of synaptic plasticity [GO:0048167]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	apical dendrite [GO:0097440]; cell [GO:0005623]; cell body [GO:0044297]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	3-phosphoinositide-dependent protein kinase binding [GO:0043423]; ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; NMDA glutamate receptor activity [GO:0004972]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein tyrosine kinase activity [GO:0004713]; ubiquitin protein ligase binding [GO:0031625]
d3b72a__d4ow1u___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	hydrolase activity [GO:0016787]
d3b75a__d2ri4a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3b75b__d2uunr___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3b75s__d5toua___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3b76a1_d5glja1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	ubiquitin-dependent protein catabolic process [GO:0006511]	cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	cytoplasm [GO:0005737]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; ubiquitin-protein transferase activity [GO:0004842]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]
d3b76b1_d1gq5a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-dependent protein catabolic process [GO:0006511]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]; beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	ubiquitin-dependent protein catabolic process [GO:0006511]	actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein-containing complex assembly [GO:0065003]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; ubiquitin-protein transferase activity [GO:0004842]	beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]
d3b78a2_d3cc4b1__1			Proteobacteria	Euryarchaeota	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d3b78c3_d1zm2a5__1			Proteobacteria	Proteobacteria	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]					NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d3b7ba2_d1ixva1__1	Metazoa	Fungi	Chordata	Ascomycota	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; C2H2 zinc finger domain binding [GO:0070742]; histone methyltransferase activity (H3-K27 specific) [GO:0046976]; histone methyltransferase activity (H3-K9 specific) [GO:0046974]; histone-lysine N-methyltransferase activity [GO:0018024]; methyltransferase activity [GO:0008168]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]; zinc ion binding [GO:0008270]; chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; histone methylation [GO:0016571]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to fungicide [GO:0060992]	cytosol [GO:0005829]; nucleus [GO:0005634]; proteasome regulatory particle binding [GO:1904855]; proteasome regulatory particle assembly [GO:0070682]	chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; histone methylation [GO:0016571]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to fungicide [GO:0060992]	proteasome regulatory particle assembly [GO:0070682]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; nucleus [GO:0005634]	C2H2 zinc finger domain binding [GO:0070742]; histone-lysine N-methyltransferase activity [GO:0018024]; histone methyltransferase activity (H3-K27 specific) [GO:0046976]; histone methyltransferase activity (H3-K9 specific) [GO:0046974]; methyltransferase activity [GO:0008168]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]; zinc ion binding [GO:0008270]	proteasome regulatory particle binding [GO:1904855]
d3b7bb__d1ihbb___1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; C2H2 zinc finger domain binding [GO:0070742]; histone methyltransferase activity (H3-K27 specific) [GO:0046976]; histone methyltransferase activity (H3-K9 specific) [GO:0046974]; histone-lysine N-methyltransferase activity [GO:0018024]; methyltransferase activity [GO:0008168]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]; zinc ion binding [GO:0008270]; chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; histone methylation [GO:0016571]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to fungicide [GO:0060992]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]; cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of phosphorylation [GO:0042326]; oligodendrocyte differentiation [GO:0048709]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; histone methylation [GO:0016571]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to fungicide [GO:0060992]	cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of phosphorylation [GO:0042326]; oligodendrocyte differentiation [GO:0048709]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	C2H2 zinc finger domain binding [GO:0070742]; histone-lysine N-methyltransferase activity [GO:0018024]; histone methyltransferase activity (H3-K27 specific) [GO:0046976]; histone methyltransferase activity (H3-K9 specific) [GO:0046974]; methyltransferase activity [GO:0008168]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]; zinc ion binding [GO:0008270]	cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]
d3b7dc__d1lfha2__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d3b7eb__d3sanb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3b7jd__d5t07c___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	plasma membrane [GO:0005886]; acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]; lipid metabolic process [GO:0006629]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	lipid metabolic process [GO:0006629]	cytoplasm [GO:0005737]	plasma membrane [GO:0005886]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]
d3b7je__d3azau___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	hydro-lyase activity [GO:0016836]
d3b7mb__d2pelc___1		Viridiplantae	Bacteroidetes	Streptophyta	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	polysaccharide catabolic process [GO:0000272]				cellulase activity [GO:0008810]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3b7mc__d3akqa___1		Fungi	Bacteroidetes	Ascomycota	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]			cellulase activity [GO:0008810]	endo-1,4-beta-xylanase activity [GO:0031176]
d3b7md__d1oa2f___1		Fungi	Bacteroidetes	Ascomycota	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]	cellulase activity [GO:0008810]
d3b7na1_d1oiza1__1	Fungi	Metazoa	Ascomycota	Chordata	nucleus [GO:0005634]; phosphatidylcholine binding [GO:0031210]; phosphatidylinositol binding [GO:0035091]	cell [GO:0005623]; cytosol [GO:0005829]; late endosome [GO:0005770]; lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin E binding [GO:0008431]; embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; lipid metabolic process [GO:0006629]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]		embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; lipid metabolic process [GO:0006629]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]	nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; late endosome [GO:0005770]	phosphatidylcholine binding [GO:0031210]; phosphatidylinositol binding [GO:0035091]	lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin E binding [GO:0008431]
d3b7na2_d1oipa2__1	Fungi	Metazoa	Ascomycota	Chordata	nucleus [GO:0005634]; phosphatidylcholine binding [GO:0031210]; phosphatidylinositol binding [GO:0035091]	cell [GO:0005623]; cytosol [GO:0005829]; late endosome [GO:0005770]; lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin E binding [GO:0008431]; embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; lipid metabolic process [GO:0006629]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]		embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; lipid metabolic process [GO:0006629]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]	nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; late endosome [GO:0005770]	phosphatidylcholine binding [GO:0031210]; phosphatidylinositol binding [GO:0035091]	lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin E binding [GO:0008431]
d3b7qb2_d4tlga2__1	Fungi	Metazoa	Ascomycota	Chordata	nucleus [GO:0005634]; phosphatidylcholine binding [GO:0031210]; phosphatidylinositol binding [GO:0035091]	lipid binding [GO:0008289]			nucleus [GO:0005634]		phosphatidylcholine binding [GO:0031210]; phosphatidylinositol binding [GO:0035091]	lipid binding [GO:0008289]
d3b7rl3_d2wo8c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3b7sa3_d2w12a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; chemotaxis [GO:0006935]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	chemotaxis [GO:0006935]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]
d3b7ta1_d4u58a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]
d3b7vb__d1fq7a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]; autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]
d3b7za1_d1olme1__1	Fungi	Metazoa	Ascomycota	Chordata	nucleus [GO:0005634]; phosphatidylcholine binding [GO:0031210]; phosphatidylinositol binding [GO:0035091]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phospholipid binding [GO:0005543]; vitamin E binding [GO:0008431]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cholesterol biosynthetic process [GO:0045540]		positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cholesterol biosynthetic process [GO:0045540]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	phosphatidylcholine binding [GO:0031210]; phosphatidylinositol binding [GO:0035091]	phospholipid binding [GO:0005543]; vitamin E binding [GO:0008431]
d3b82a2_d1vqnb1__1			Proteobacteria	Euryarchaeota	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d3b82c2_d1d1na___1			Proteobacteria	Firmicutes	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation initiation factor activity [GO:0003743]				cytoplasm [GO:0005737]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation initiation factor activity [GO:0003743]
d3b82c2_d2ogmb1__1			Proteobacteria	Deinococcus-Thermus	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d3b82e2_d1aipb1__1			Proteobacteria	Deinococcus-Thermus	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3b82e3_d3b82c5__1			Proteobacteria	Proteobacteria	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]					NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d3b83a1_d1x5xa1__1		Metazoa		Chordata		acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; vesicle membrane [GO:0012506]; RNA binding [GO:0003723]; cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286]		cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286]		acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; vesicle membrane [GO:0012506]		RNA binding [GO:0003723]
d3b83d1_d1fg9d1__1		Metazoa		Chordata		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interferon-gamma receptor activity [GO:0004906]; astrocyte activation [GO:0048143]; cytokine-mediated signaling pathway [GO:0019221]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of gene expression [GO:0010628]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; response to virus [GO:0009615]; signal transduction [GO:0007165]		astrocyte activation [GO:0048143]; cytokine-mediated signaling pathway [GO:0019221]; interferon-gamma-mediated signaling pathway [GO:0060333]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of gene expression [GO:0010628]; positive regulation of tumor necrosis factor secretion [GO:1904469]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; response to virus [GO:0009615]; signal transduction [GO:0007165]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interferon-gamma receptor activity [GO:0004906]
d3b83e1_d2edda1__1		Metazoa		Chordata		axon [GO:0030424]; cytosol [GO:0005829]; integral component of postsynaptic density membrane [GO:0099061]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; netrin receptor activity [GO:0005042]; transmembrane signaling receptor activity [GO:0004888]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dorsal/ventral axon guidance [GO:0033563]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of netrin-activated signaling pathway [GO:1902842]; negative regulation of neuron projection development [GO:0010977]; neuron migration [GO:0001764]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of neuron death [GO:1901214]; spinal cord ventral commissure morphogenesis [GO:0021965]		anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dorsal/ventral axon guidance [GO:0033563]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of netrin-activated signaling pathway [GO:1902842]; negative regulation of neuron projection development [GO:0010977]; neuron migration [GO:0001764]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of neuron death [GO:1901214]; spinal cord ventral commissure morphogenesis [GO:0021965]		axon [GO:0030424]; cytosol [GO:0005829]; integral component of postsynaptic density membrane [GO:0099061]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]		netrin receptor activity [GO:0005042]; transmembrane signaling receptor activity [GO:0004888]
d3b8ax2_d1lotb2__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; cellular glucose homeostasis [GO:0001678]; fructose import [GO:0032445]; fructose metabolic process [GO:0006000]; glucose import [GO:0046323]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cellular glucose homeostasis [GO:0001678]; fructose import [GO:0032445]; fructose metabolic process [GO:0006000]; glucose import [GO:0046323]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3b8db__d3tmqa___1	Metazoa		Chordata	Proteobacteria	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	I band [GO:0031674]; M band [GO:0031430]	cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]
d3b8dc__d3pb2e1__1	Metazoa		Chordata	Thermotogae	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	I band [GO:0031674]; M band [GO:0031430]	cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3b8dd__d1w56a___1	Metazoa		Chordata	Proteobacteria	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]; heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	I band [GO:0031674]; M band [GO:0031430]	cytosol [GO:0005829]	fructose-bisphosphate aldolase activity [GO:0004332]	porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]
d3b8ea3_d1xp5a1__1	Metazoa	Metazoa	Chordata	Chordata	sodium:potassium-exchanging ATPase complex [GO:0005890]; ion channel regulator activity [GO:0099106]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; potassium ion import across plasma membrane [GO:1990573]; regulation of ion transport [GO:0043269]; sodium ion export across plasma membrane [GO:0036376]; transmembrane transport [GO:0055085]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; potassium ion import across plasma membrane [GO:1990573]; regulation of ion transport [GO:0043269]; sodium ion export across plasma membrane [GO:0036376]; transmembrane transport [GO:0055085]	calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	sodium:potassium-exchanging ATPase complex [GO:0005890]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]	ion channel regulator activity [GO:0099106]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]
d3b8ec3_d5avqa2__1	Metazoa	Metazoa	Chordata	Chordata	sodium:potassium-exchanging ATPase complex [GO:0005890]; ion channel regulator activity [GO:0099106]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; potassium ion import across plasma membrane [GO:1990573]; regulation of ion transport [GO:0043269]; sodium ion export across plasma membrane [GO:0036376]; transmembrane transport [GO:0055085]	integral component of membrane [GO:0016021]; ion channel regulator activity [GO:0099106]; ion transport [GO:0006811]; regulation of ion transport [GO:0043269]	establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; potassium ion import across plasma membrane [GO:1990573]; regulation of ion transport [GO:0043269]; sodium ion export across plasma membrane [GO:0036376]; transmembrane transport [GO:0055085]	ion transport [GO:0006811]; regulation of ion transport [GO:0043269]	sodium:potassium-exchanging ATPase complex [GO:0005890]	integral component of membrane [GO:0016021]	ion channel regulator activity [GO:0099106]	ion channel regulator activity [GO:0099106]
d3b8ha2_d1jj2b___1			Proteobacteria	Euryarchaeota	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d3b8hc2_d4tmza2__1		Fungi	Proteobacteria	Ascomycota	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; translation initiation factor activity [GO:0003743]				cytoplasm [GO:0005737]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; translation initiation factor activity [GO:0003743]
d3b8he2_d3cw2a2__1			Proteobacteria	Crenarchaeota	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d3b95a1_d3twtd1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]
d3b95b__d2dzoa___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	cytosol [GO:0005829]; nucleus [GO:0005634]; proteasome regulatory particle binding [GO:1904855]; proteasome regulatory particle assembly [GO:0070682]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	proteasome regulatory particle assembly [GO:0070682]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	proteasome regulatory particle binding [GO:1904855]
d3b97a2_d3r25b2__1	Metazoa		Chordata	Proteobacteria	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	cellular amino acid catabolic process [GO:0009063]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	magnesium ion binding [GO:0000287]
d3b97d1_d3q45a1__1	Metazoa		Chordata	Bacteroidetes	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	peptide metabolic process [GO:0006518]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d3b97d2_d2al1a1__1	Metazoa	Fungi	Chordata	Ascomycota	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3b9cc__d3uv9a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; intracellular [GO:0005622]; carbohydrate binding [GO:0030246]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]; identical protein binding [GO:0042802]; signaling pattern recognition receptor activity [GO:0008329]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipopolysaccharide-mediated signaling pathway [GO:0031664]; regulation of protein localization [GO:0032880]		activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipopolysaccharide-mediated signaling pathway [GO:0031664]; regulation of protein localization [GO:0032880]	cytoplasm [GO:0005737]; intracellular [GO:0005622]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]	carbohydrate binding [GO:0030246]	identical protein binding [GO:0042802]; signaling pattern recognition receptor activity [GO:0008329]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d3b9ja1_d3hrdd2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	FAD binding [GO:0071949]; nicotinate dehydrogenase activity [GO:0050138]; cofactor catabolic process [GO:0051187]	xanthine catabolic process [GO:0009115]	cofactor catabolic process [GO:0051187]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	FAD binding [GO:0071949]; nicotinate dehydrogenase activity [GO:0050138]
d3b9ja2_d5byrb1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]
d3b9ji2_d2w3sa1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3b9ji2_d3aefb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	xanthine catabolic process [GO:0009115]	mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d3b9jj1_d3am9a4__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d3b9jj2_d2bvfb1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]
d3b9jk1_d1n63b1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3b9ka__d1ruqh1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3b9ka__d3oazk2__1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]	
d3b9kb__d1mchb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]	
d3b9kc1_d5jorl2__1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]	
d3b9kc2_d2vyre___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]
d3b9kf__d2atpc___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]	coreceptor activity [GO:0015026]; MHC class I protein binding [GO:0042288]
d3b9la2_d5otba1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d3b9la3_d2xvva3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3b9ma1_d2bxna2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3b9na__d1rhca___1			Firmicutes	Euryarchaeota	monooxygenase activity [GO:0004497]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]					monooxygenase activity [GO:0004497]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3b9oa__d1brld___1			Firmicutes	Proteobacteria	monooxygenase activity [GO:0004497]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	alkanal monooxygenase (FMN-linked) activity [GO:0047646]; bioluminescence [GO:0008218]		bioluminescence [GO:0008218]			monooxygenase activity [GO:0004497]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	alkanal monooxygenase (FMN-linked) activity [GO:0047646]
d3b9va__d1v7mm1__1		Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]		cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]
d3b9vc__d5sx5l2__1		Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d3ba0a2_d1rtga___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	angiogenesis [GO:0001525]; blood vessel maturation [GO:0001955]; bone trabecula formation [GO:0060346]; cellular protein metabolic process [GO:0044267]; cellular response to amino acid stimulus [GO:0071230]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; tissue remodeling [GO:0048771]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3ba4b1_d1i1ba___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d3ba5b1_d3fjeb1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3ba6a4_d5avwa4__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	integral component of membrane [GO:0016021]; ion channel regulator activity [GO:0099106]; ion transport [GO:0006811]; regulation of ion transport [GO:0043269]	calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	ion transport [GO:0006811]; regulation of ion transport [GO:0043269]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]	integral component of membrane [GO:0016021]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]	ion channel regulator activity [GO:0099106]
d3ba7b1_d3bava1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3baaa__d2q2ta2__1			Firmicutes		DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]			DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; DNA ligase (ATP) activity [GO:0003910]
d3baba__d4ucua___1			Firmicutes	Proteobacteria	DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; base-excision repair, DNA ligation [GO:0006288]; DNA replication [GO:0006260]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	base-excision repair, DNA ligation [GO:0006288]; DNA replication [GO:0006260]		cytosol [GO:0005829]	DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]
d3bada__d1afca___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3baga1_d1e0oa___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3baha1_d1jt5b1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3baha1_d1twma___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d3bahb1_d1j0sa___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d3baka1_d3s5ya2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d3baqa1_d1q04b___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3bara2_d3femb___1		Fungi	Apicomplexa	Ascomycota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]		glutaminase complex [GO:1903600]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3barb2_d4o8rj___1			Apicomplexa	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3bawa1_d1bvza2__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d3bawa1_d2zida2__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cytoplasm [GO:0005737]; glucan 1,6-alpha-glucosidase activity [GO:0043896]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	glucan 1,6-alpha-glucosidase activity [GO:0043896]
d3baxa1_d5brqd2__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cytoplasm [GO:0005737]; alpha,alpha-phosphotrehalase activity [GO:0008788]; metal ion binding [GO:0046872]; trehalose catabolic process [GO:0005993]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	trehalose catabolic process [GO:0005993]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha,alpha-phosphotrehalase activity [GO:0008788]; metal ion binding [GO:0046872]
d3baya2_d4lypa1__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	
d3bb2b1_d2miba___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	autophagosome [GO:0005776]; cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; vesicle [GO:0031982]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; astrocyte activation [GO:0048143]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-6 production [GO:0032635]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; memory [GO:0007613]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of branching morphogenesis of a nerve [GO:2000173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of glutamate secretion [GO:0014050]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of synaptic transmission [GO:0050805]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell death [GO:0010942]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; social behavior [GO:0035176]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; astrocyte activation [GO:0048143]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-6 production [GO:0032635]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; memory [GO:0007613]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of branching morphogenesis of a nerve [GO:2000173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of glutamate secretion [GO:0014050]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of synaptic transmission [GO:0050805]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell death [GO:0010942]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; social behavior [GO:0035176]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	autophagosome [GO:0005776]; cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; vesicle [GO:0031982]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d3bbbc__d3q86a___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3bbca__d1jxve___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]; cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	cellular response to drug [GO:0035690]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; hippocampus development [GO:0021766]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; nucleobase-containing small molecule interconversion [GO:0015949]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of neuron projection development [GO:0010976]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of apoptotic process [GO:0042981]; response to amine [GO:0014075]; response to cAMP [GO:0051591]; response to testosterone [GO:0033574]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intermediate filament [GO:0005882]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; deoxyribonuclease activity [GO:0004536]; enzyme binding [GO:0019899]; gamma-tubulin binding [GO:0043015]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; intermediate filament binding [GO:0019215]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; single-stranded DNA binding [GO:0003697]
d3bbca__d4f4ac___1	Metazoa		Chordata		cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; posttranscriptional regulation of gene expression [GO:0010608]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; posttranscriptional regulation of gene expression [GO:0010608]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3bbeb__d3n4ja1__1			Euryarchaeota	Proteobacteria	nucleolus [GO:0005730]; small-subunit processome [GO:0032040]; protein homodimerization activity [GO:0042803]; rRNA (pseudouridine) methyltransferase activity [GO:0070037]; rRNA binding [GO:0019843]; rRNA base methylation [GO:0070475]	cytoplasm [GO:0005737]; RNA binding [GO:0003723]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; tRNA methyltransferase activity [GO:0008175]; wobble position cytosine ribose methylation [GO:0002131]; wobble position uridine ribose methylation [GO:0002132]	rRNA base methylation [GO:0070475]	wobble position cytosine ribose methylation [GO:0002131]; wobble position uridine ribose methylation [GO:0002132]	nucleolus [GO:0005730]; small-subunit processome [GO:0032040]	cytoplasm [GO:0005737]	protein homodimerization activity [GO:0042803]; rRNA (pseudouridine) methyltransferase activity [GO:0070037]; rRNA binding [GO:0019843]	RNA binding [GO:0003723]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; tRNA methyltransferase activity [GO:0008175]
d3bbfa__d3ztrf___1	Metazoa		Chordata	Aquificae	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3bbfc__d1b99c___1	Metazoa		Chordata		cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3bbfd__d3fbed1__1	Metazoa		Chordata		cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3bbrb2_d2o7ui___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d3bbsb__d1kwxb1__1		Metazoa		Chordata		collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]		complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]		collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]		calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d3bbsc__d1t8ca1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d3bbsd__d1kmb21__1		Metazoa		Chordata		collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]		complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]		collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]		calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d3bbxe1_d2awbe1__1			Proteobacteria		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]		5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]	
d3bbxm1_d1y69k1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	translation [GO:0006412]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]	cytosolic large ribosomal subunit [GO:0022625]	5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d3bbxs1_d2zjqp1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	translation [GO:0006412]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]	cytosolic large ribosomal subunit [GO:0022625]	5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d3bbxu1_d3df4u1__1			Proteobacteria		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]		5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]	
d3bbxz1_d2qbcz1__1			Proteobacteria		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; 5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]; negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		negative regulation of translation [GO:0017148]; response to radiation [GO:0009314]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]		5S rRNA binding [GO:0008097]; structural constituent of ribosome [GO:0003735]	
d3bc1a__d3hqdb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; exocytic vesicle [GO:0070382]; extrinsic component of plasma membrane [GO:0019897]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]; neurexin family protein binding [GO:0042043]; phosphatase binding [GO:0019902]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; Rab GTPase binding [GO:0017137]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of mucus secretion [GO:0070257]; protein localization to plasma membrane [GO:0072659]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; kinesin complex [GO:0005871]; membrane [GO:0016020]; microtubule [GO:0005874]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; ATP binding [GO:0005524]; ATP-dependent microtubule motor activity, plus-end-directed [GO:0008574]; ATPase activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; protein kinase binding [GO:0019901]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; regulation of mitotic centrosome separation [GO:0046602]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; spindle organization [GO:0007051]	exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of mucus secretion [GO:0070257]; protein localization to plasma membrane [GO:0072659]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; regulation of mitotic centrosome separation [GO:0046602]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; spindle organization [GO:0007051]	cytoplasm [GO:0005737]; exocytic vesicle [GO:0070382]; extrinsic component of plasma membrane [GO:0019897]; melanosome [GO:0042470]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; kinesin complex [GO:0005871]; membrane [GO:0016020]; microtubule [GO:0005874]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]	neurexin family protein binding [GO:0042043]; phosphatase binding [GO:0019902]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; Rab GTPase binding [GO:0017137]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; ATP-dependent microtubule motor activity, plus-end-directed [GO:0008574]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; protein kinase binding [GO:0019901]
d3bc4a__d3sa4a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3bc6b__d2it5a___1		Metazoa		Chordata		cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]		adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]
d3bc6b__d3alub___1		Metazoa		Echinodermata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d3bc6d__d1wmzc___1		Metazoa		Echinodermata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d3bc6d__d2riba1__1		Metazoa		Chordata		clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]		cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]		clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]		carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d3bc7c__d1tlgb___1		Metazoa		Chordata		carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]
d3bcca1_d1hr6d2__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	protein processing involved in protein targeting to mitochondrion [GO:0006627]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3bccb1_d2fqoa___1	Metazoa		Chordata	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]; quorum sensing [GO:0009372]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	quorum sensing [GO:0009372]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]
d3bcob__d2e33b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	RNA phosphodiester bond hydrolysis [GO:0090501]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d3bcqb__d2uuli___1	Metazoa		Chordata		hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3bd3b__d1fdll1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3bd4a__d4huwc2__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3bdba__d4mywc___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; dendrite [GO:0030425]; extracellular region [GO:0005576]; growth cone membrane [GO:0032584]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of presynaptic active zone membrane [GO:0099059]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adherens junction organization [GO:0034332]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; desmosome organization [GO:0002934]; enamel mineralization [GO:0070166]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; immune response [GO:0006955]; iron ion transport [GO:0006826]; lens morphogenesis in camera-type eye [GO:0002089]; protein localization to cell junction [GO:1902414]; regulation of synapse assembly [GO:0051963]; retina development in camera-type eye [GO:0060041]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		adherens junction organization [GO:0034332]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; desmosome organization [GO:0002934]; enamel mineralization [GO:0070166]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; immune response [GO:0006955]; iron ion transport [GO:0006826]; lens morphogenesis in camera-type eye [GO:0002089]; protein localization to cell junction [GO:1902414]; regulation of synapse assembly [GO:0051963]; retina development in camera-type eye [GO:0060041]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]	adherens junction [GO:0005912]; apical junction complex [GO:0043296]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; dendrite [GO:0030425]; extracellular region [GO:0005576]; growth cone membrane [GO:0032584]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of presynaptic active zone membrane [GO:0099059]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]
d3bdbb__d1op3m1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d3bdbc__d2w9lx___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]		actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	integral component of membrane [GO:0016021]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3bdbe__d3v0wl1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]			
d3bdja4_d1jrog3__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3bdja4_d3eubb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d3bdjb3_d1uxya1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; UDP-N-acetylmuramate dehydrogenase activity [GO:0008762]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	xanthine catabolic process [GO:0009115]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; UDP-N-acetylmuramate dehydrogenase activity [GO:0008762]
d3bdmp__d5l5se___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3bdmq__d5trry___1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	threonine-type endopeptidase activity [GO:0004298]
d3bdmr__d4hrdw___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3bdmu__d4qvwl___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3bdmv__d5l5as___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3bdmw__d5l5yy___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3bdmy__d4qv4c___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3bdmz__d4inuh___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3bdwa__d2msba___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; carbohydrate binding [GO:0030246]; MHC class I protein complex binding [GO:0023024]; MHC class Ib protein binding, via antigen binding groove [GO:0023030]; protein antigen binding [GO:1990405]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; natural killer cell mediated immunity [GO:0002228]; regulation of immune response [GO:0050776]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; natural killer cell mediated immunity [GO:0002228]; regulation of immune response [GO:0050776]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; MHC class Ib protein binding, via antigen binding groove [GO:0023030]; MHC class I protein complex binding [GO:0023024]; protein antigen binding [GO:1990405]; transmembrane signaling receptor activity [GO:0004888]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d3bdxa__d3bvne___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3be1l1_d3hujf2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3be1l1_d5acmb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]
d3be1l2_d4nuja1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3be7g2_d1v79a___1		Metazoa		Chordata		cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]; adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]		adenosine catabolic process [GO:0006154]; cell adhesion [GO:0007155]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]		cell junction [GO:0030054]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; lysosome [GO:0005764]		adenosine deaminase activity [GO:0004000]; zinc ion binding [GO:0008270]
d3bena__d2ij7f___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]
d3benb__d4l4ga___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3bepa1_d4n97b3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3bepa2_d1vyma1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d3bepb2_d6ap4m1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d3beua__d1gbka___1			Actinobacteria	Proteobacteria	serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]				extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d3beua__d2bd3a___1		Metazoa	Actinobacteria	Chordata	serine-type endopeptidase activity [GO:0004252]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]		elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]		extracellular space [GO:0005615]	serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3bexb2_d4fpab4__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	coenzyme A biosynthetic process [GO:0015937]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d3bexc1_d4phtz1__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	type II protein secretion system complex [GO:0015627]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein secretion by the type II secretion system [GO:0015628]	coenzyme A biosynthetic process [GO:0015937]	protein secretion by the type II secretion system [GO:0015628]	cytoplasm [GO:0005737]	type II protein secretion system complex [GO:0015627]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d3bf1a1_d4iz9a2__1			Thermotogae	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	coenzyme A biosynthetic process [GO:0015937]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]
d3bf1a2_d5aqpe2__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	coenzyme A biosynthetic process [GO:0015937]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3bf1c1_d3bexe2__1			Thermotogae	Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d3bf1d2_d1z05a2__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	coenzyme A biosynthetic process [GO:0015937]	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]
d3bf1e1_d2q36a2__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	coenzyme A biosynthetic process [GO:0015937]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3bf1f1_d2ch6d1__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	coenzyme A biosynthetic process [GO:0015937]	N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]
d3bf1f2_d1hlua2__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; calyx of Held [GO:0044305]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dense body [GO:0097433]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic actin cytoskeleton [GO:0098871]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; nitric-oxide synthase binding [GO:0050998]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973]; Tat protein binding [GO:0030957]; axonogenesis [GO:0007409]; cell motility [GO:0048870]; cellular response to cytochalasin B [GO:0072749]; negative regulation of protein binding [GO:0032091]; regulation of norepinephrine uptake [GO:0051621]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of transmembrane transporter activity [GO:0022898]; synaptic vesicle endocytosis [GO:0048488]	coenzyme A biosynthetic process [GO:0015937]	axonogenesis [GO:0007409]; cell motility [GO:0048870]; cellular response to cytochalasin B [GO:0072749]; negative regulation of protein binding [GO:0032091]; regulation of norepinephrine uptake [GO:0051621]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of transmembrane transporter activity [GO:0022898]; synaptic vesicle endocytosis [GO:0048488]	cytoplasm [GO:0005737]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; axon [GO:0030424]; calyx of Held [GO:0044305]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dense body [GO:0097433]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; NuA4 histone acetyltransferase complex [GO:0035267]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic actin cytoskeleton [GO:0098871]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinesin binding [GO:0019894]; nitric-oxide synthase binding [GO:0050998]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic actin cytoskeleton [GO:0098973]; Tat protein binding [GO:0030957]
d3bf3c1_d3h46o1__1			Thermotogae	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	coenzyme A biosynthetic process [GO:0015937]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d3bfaa__d3b88b___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]; courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]		courtship behavior [GO:0007619]; olfactory behavior [GO:0042048]; response to ethanol [GO:0045471]; response to pheromone [GO:0019236]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]	odorant binding [GO:0005549]	dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; pheromone binding [GO:0005550]
d3bfra1_d1gn6a1__1	Fungi		Ascomycota	Actinobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; age-dependent response to oxidative stress involved in chronological cell aging [GO:0001324]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; reactive oxygen species metabolic process [GO:0072593]; replicative cell aging [GO:0001302]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	age-dependent response to oxidative stress involved in chronological cell aging [GO:0001324]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; reactive oxygen species metabolic process [GO:0072593]; replicative cell aging [GO:0001302]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3bfta__d3ppnb___1	Metazoa		Chordata	Firmicutes	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; amino acid transport [GO:0006865]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	amino acid transport [GO:0006865]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	transmembrane transporter activity [GO:0022857]
d3bfua2_d1lfga1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d3bfua2_d3tcge___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]
d3bfub__d4nf0g___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; C4-dicarboxylate transport [GO:0015740]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	C4-dicarboxylate transport [GO:0015740]; transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d3bgbb__d3n3ia1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3bgca__d5p24a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3bgda__d2h11a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]; drug metabolic process [GO:0017144]	cytosol [GO:0005829]; S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]; drug metabolic process [GO:0017144]; methylation [GO:0032259]; nucleobase-containing compound metabolic process [GO:0006139]	drug metabolic process [GO:0017144]	drug metabolic process [GO:0017144]; methylation [GO:0032259]; nucleobase-containing compound metabolic process [GO:0006139]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]	S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]
d3bgda__d4iwnb___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]; drug metabolic process [GO:0017144]	cytosol [GO:0005829]; carboxyl- or carbamoyltransferase activity [GO:0016743]; S-adenosyl-L-methionine binding [GO:1904047]; tRNA wobble uridine modification [GO:0002098]	drug metabolic process [GO:0017144]	tRNA wobble uridine modification [GO:0002098]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]	carboxyl- or carbamoyltransferase activity [GO:0016743]; S-adenosyl-L-methionine binding [GO:1904047]
d3bgdb__d3p9kc2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]; drug metabolic process [GO:0017144]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	drug metabolic process [GO:0017144]		cytoplasm [GO:0005737]		S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]
d3bgfl2_d1iaii1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3bgia__d3b7pb___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]; drug metabolic process [GO:0017144]	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	drug metabolic process [GO:0017144]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]	spermidine synthase activity [GO:0004766]
d3bgma1_d5x2ol2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; G protein-coupled receptor activity [GO:0004930]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	G protein-coupled receptor activity [GO:0004930]
d3bgmb2_d2h9ga2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte migration [GO:0050900]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to endoplasmic reticulum stress [GO:0034976]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	signaling receptor activity [GO:0038023]; TRAIL binding [GO:0045569]
d3bgxa__d4iske1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytosol [GO:0005829]	cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]
d3bh6a__d6bcaf___1	Metazoa	Metazoa	Chordata	Chordata	axoneme [GO:0005930]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary transition zone [GO:0035869]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; photoreceptor connecting cilium [GO:0032391]; spindle microtubule [GO:0005876]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; cilium assembly [GO:0060271]; Golgi to plasma membrane transport [GO:0006893]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; mitotic cytokinesis [GO:0000281]; photoreceptor cell development [GO:0042461]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to ciliary membrane [GO:1903441]; protein localization to cilium [GO:0061512]; small GTPase mediated signal transduction [GO:0007264]; smoothened signaling pathway [GO:0007224]	actin filament [GO:0005884]; cell cortex [GO:0005938]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; cAMP-dependent protein kinase activity [GO:0004691]; MAP-kinase scaffold activity [GO:0005078]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; protein kinase A binding [GO:0051018]; Rho GTPase binding [GO:0017048]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of glucocorticoid mediated signaling pathway [GO:1900169]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056]	cilium assembly [GO:0060271]; Golgi to plasma membrane transport [GO:0006893]; intraciliary transport [GO:0042073]; kidney development [GO:0001822]; mitotic cytokinesis [GO:0000281]; photoreceptor cell development [GO:0042461]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to ciliary membrane [GO:1903441]; protein localization to cilium [GO:0061512]; small GTPase mediated signal transduction [GO:0007264]; smoothened signaling pathway [GO:0007224]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of glucocorticoid mediated signaling pathway [GO:1900169]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056]	axoneme [GO:0005930]; centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary transition zone [GO:0035869]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; photoreceptor connecting cilium [GO:0032391]; spindle microtubule [GO:0005876]	actin filament [GO:0005884]; cell cortex [GO:0005938]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	GDP binding [GO:0019003]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]	cAMP-dependent protein kinase activity [GO:0004691]; MAP-kinase scaffold activity [GO:0005078]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; protein kinase A binding [GO:0051018]; Rho GTPase binding [GO:0017048]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]
d3bh8b2_d1lo3x2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3bh8b2_d4w81a___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3bh9a1_d3kdma2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3bh9b2_d4u0qd2__1	Metazoa		Chordata	Apicomplexa	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3bhbb__d2xv6d1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3bhea__d5p67a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3bheb__d2aoeb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3bheb__d5p17a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3bhfa2_d1ddoc2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	tetrahydrofolate metabolic process [GO:0046653]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	sarcosine oxidase activity [GO:0008115]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d3bhfb2_d1kifc2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]; D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]; D-alanine catabolic process [GO:0055130]; D-serine catabolic process [GO:0036088]; dopamine biosynthetic process [GO:0042416]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	tetrahydrofolate metabolic process [GO:0046653]	D-alanine catabolic process [GO:0055130]; dopamine biosynthetic process [GO:0042416]; D-serine catabolic process [GO:0036088]; oxidation-reduction process [GO:0055114]; proline catabolic process [GO:0006562]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; peroxisomal membrane [GO:0005778]	sarcosine oxidase activity [GO:0008115]	D-amino-acid oxidase activity [GO:0003884]; FAD binding [GO:0071949]; protein dimerization activity [GO:0046983]
d3bhfb2_d2v5za2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	tetrahydrofolate metabolic process [GO:0046653]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	sarcosine oxidase activity [GO:0008115]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d3bhla__d1aiqa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytosol [GO:0005829]	cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]
d3bhra__d1vzda___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d3bhtb2_d1xo2a2__1	Metazoa		Chordata		Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell cycle [GO:0007049]; cell division [GO:0051301]; modulation by virus of host cell cycle [GO:0060153]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell cycle [GO:0007049]; cell division [GO:0051301]; modulation by virus of host cell cycle [GO:0060153]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]		ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	
d3bhub1_d4bcib1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3bhub2_d2ccid2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d3bhud1_d1n4ma1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]; androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d3bikc__d3whxb1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of T cell apoptotic process [GO:0070234]		adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of T cell apoptotic process [GO:0070234]		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]			
d3bimb__d1qdwa___1	Metazoa	Metazoa	Chordata	Chordata	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; intronic transcription regulatory region sequence-specific DNA binding [GO:0001161]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; actin cytoskeleton organization [GO:0030036]; B cell differentiation [GO:0030183]; cell morphogenesis [GO:0000902]; cellular response to DNA damage stimulus [GO:0006974]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte development [GO:0048821]; germinal center formation [GO:0002467]; inflammatory response [GO:0006954]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cellular senescence [GO:2000773]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mitotic cell cycle DNA replication [GO:1903464]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular component movement [GO:0051272]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of germinal center formation [GO:0002634]; regulation of GTPase activity [GO:0043087]; regulation of immune response [GO:0050776]; regulation of inflammatory response [GO:0050727]; regulation of memory T cell differentiation [GO:0043380]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; type 2 immune response [GO:0042092]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	actin cytoskeleton organization [GO:0030036]; B cell differentiation [GO:0030183]; cell morphogenesis [GO:0000902]; cellular response to DNA damage stimulus [GO:0006974]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte development [GO:0048821]; germinal center formation [GO:0002467]; inflammatory response [GO:0006954]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cell growth [GO:0030308]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mitotic cell cycle DNA replication [GO:1903464]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular component movement [GO:0051272]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of germinal center formation [GO:0002634]; regulation of GTPase activity [GO:0043087]; regulation of immune response [GO:0050776]; regulation of inflammatory response [GO:0050727]; regulation of memory T cell differentiation [GO:0043380]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; type 2 immune response [GO:0042092]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; intronic transcription regulatory region sequence-specific DNA binding [GO:0001161]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]
d3bimg__d5bxbb1__1	Metazoa	Metazoa	Chordata	Chordata	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; intronic transcription regulatory region sequence-specific DNA binding [GO:0001161]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; actin cytoskeleton organization [GO:0030036]; B cell differentiation [GO:0030183]; cell morphogenesis [GO:0000902]; cellular response to DNA damage stimulus [GO:0006974]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte development [GO:0048821]; germinal center formation [GO:0002467]; inflammatory response [GO:0006954]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cellular senescence [GO:2000773]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mitotic cell cycle DNA replication [GO:1903464]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular component movement [GO:0051272]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of germinal center formation [GO:0002634]; regulation of GTPase activity [GO:0043087]; regulation of immune response [GO:0050776]; regulation of inflammatory response [GO:0050727]; regulation of memory T cell differentiation [GO:0043380]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; type 2 immune response [GO:0042092]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; identical protein binding [GO:0042802]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; protein homooligomerization [GO:0051260]	actin cytoskeleton organization [GO:0030036]; B cell differentiation [GO:0030183]; cell morphogenesis [GO:0000902]; cellular response to DNA damage stimulus [GO:0006974]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte development [GO:0048821]; germinal center formation [GO:0002467]; inflammatory response [GO:0006954]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cell growth [GO:0030308]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mitotic cell cycle DNA replication [GO:1903464]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular component movement [GO:0051272]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of germinal center formation [GO:0002634]; regulation of GTPase activity [GO:0043087]; regulation of immune response [GO:0050776]; regulation of inflammatory response [GO:0050727]; regulation of memory T cell differentiation [GO:0043380]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; type 2 immune response [GO:0042092]	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein homooligomerization [GO:0051260]	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; intronic transcription regulatory region sequence-specific DNA binding [GO:0001161]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]	identical protein binding [GO:0042802]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]
d3bimh__d4u2ma2__1	Metazoa	Metazoa	Chordata	Chordata	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; intronic transcription regulatory region sequence-specific DNA binding [GO:0001161]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; actin cytoskeleton organization [GO:0030036]; B cell differentiation [GO:0030183]; cell morphogenesis [GO:0000902]; cellular response to DNA damage stimulus [GO:0006974]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte development [GO:0048821]; germinal center formation [GO:0002467]; inflammatory response [GO:0006954]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cellular senescence [GO:2000773]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mitotic cell cycle DNA replication [GO:1903464]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular component movement [GO:0051272]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of germinal center formation [GO:0002634]; regulation of GTPase activity [GO:0043087]; regulation of immune response [GO:0050776]; regulation of inflammatory response [GO:0050727]; regulation of memory T cell differentiation [GO:0043380]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; type 2 immune response [GO:0042092]	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; intronic transcription regulatory region sequence-specific DNA binding [GO:0001161]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; actin cytoskeleton organization [GO:0030036]; B cell differentiation [GO:0030183]; cell morphogenesis [GO:0000902]; cellular response to DNA damage stimulus [GO:0006974]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte development [GO:0048821]; germinal center formation [GO:0002467]; inflammatory response [GO:0006954]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cellular senescence [GO:2000773]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mitotic cell cycle DNA replication [GO:1903464]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular component movement [GO:0051272]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of germinal center formation [GO:0002634]; regulation of GTPase activity [GO:0043087]; regulation of immune response [GO:0050776]; regulation of inflammatory response [GO:0050727]; regulation of memory T cell differentiation [GO:0043380]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; type 2 immune response [GO:0042092]	actin cytoskeleton organization [GO:0030036]; B cell differentiation [GO:0030183]; cell morphogenesis [GO:0000902]; cellular response to DNA damage stimulus [GO:0006974]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte development [GO:0048821]; germinal center formation [GO:0002467]; inflammatory response [GO:0006954]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cell growth [GO:0030308]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mitotic cell cycle DNA replication [GO:1903464]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular component movement [GO:0051272]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of germinal center formation [GO:0002634]; regulation of GTPase activity [GO:0043087]; regulation of immune response [GO:0050776]; regulation of inflammatory response [GO:0050727]; regulation of memory T cell differentiation [GO:0043380]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; type 2 immune response [GO:0042092]	actin cytoskeleton organization [GO:0030036]; B cell differentiation [GO:0030183]; cell morphogenesis [GO:0000902]; cellular response to DNA damage stimulus [GO:0006974]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte development [GO:0048821]; germinal center formation [GO:0002467]; inflammatory response [GO:0006954]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cell growth [GO:0030308]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mitotic cell cycle DNA replication [GO:1903464]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular component movement [GO:0051272]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of germinal center formation [GO:0002634]; regulation of GTPase activity [GO:0043087]; regulation of immune response [GO:0050776]; regulation of inflammatory response [GO:0050727]; regulation of memory T cell differentiation [GO:0043380]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; type 2 immune response [GO:0042092]	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; intronic transcription regulatory region sequence-specific DNA binding [GO:0001161]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]	chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; intronic transcription regulatory region sequence-specific DNA binding [GO:0001161]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]
d3biwe1_d2a6ya1__1	Metazoa	Fungi	Chordata	Ascomycota	cell junction [GO:0030054]; cell projection [GO:0042995]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; vesicle [GO:0031982]; acetylcholine receptor binding [GO:0033130]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; adult behavior [GO:0030534]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; learning [GO:0007612]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuromuscular process controlling balance [GO:0050885]; neurotransmitter secretion [GO:0007269]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein heterotetramerization [GO:0051290]; regulation of grooming behavior [GO:2000821]; synapse assembly [GO:0007416]; vesicle docking involved in exocytosis [GO:0006904]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; fungal-type vacuole membrane [GO:0000329]; Golgi membrane [GO:0000139]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]; carbohydrate derivative binding [GO:0097367]; mannose binding [GO:0005537]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]	adult behavior [GO:0030534]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; learning [GO:0007612]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuromuscular process controlling balance [GO:0050885]; neurotransmitter secretion [GO:0007269]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein heterotetramerization [GO:0051290]; regulation of grooming behavior [GO:2000821]; synapse assembly [GO:0007416]; vesicle docking involved in exocytosis [GO:0006904]	endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]	cell junction [GO:0030054]; cell projection [GO:0042995]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; vesicle [GO:0031982]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; fungal-type vacuole membrane [GO:0000329]; Golgi membrane [GO:0000139]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]	acetylcholine receptor binding [GO:0033130]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]	carbohydrate derivative binding [GO:0097367]; mannose binding [GO:0005537]
d3biwg1_d1q56a1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cell projection [GO:0042995]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; vesicle [GO:0031982]; acetylcholine receptor binding [GO:0033130]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; adult behavior [GO:0030534]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; learning [GO:0007612]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuromuscular process controlling balance [GO:0050885]; neurotransmitter secretion [GO:0007269]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein heterotetramerization [GO:0051290]; regulation of grooming behavior [GO:2000821]; synapse assembly [GO:0007416]; vesicle docking involved in exocytosis [GO:0006904]	axon [GO:0030424]; basal part of cell [GO:0045178]; basement membrane [GO:0005604]; cell junction [GO:0030054]; extracellular matrix [GO:0031012]; extracellular matrix of synaptic cleft [GO:0098965]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; synapse [GO:0045202]; acetylcholine receptor regulator activity [GO:0030548]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; extracellular matrix binding [GO:0050840]; glycosaminoglycan binding [GO:0005539]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; laminin binding [GO:0043236]; laminin-1 binding [GO:0043237]; serine-type endopeptidase inhibitor activity [GO:0004867]; sialic acid binding [GO:0033691]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; negative regulation of neuron projection development [GO:0010977]; negative regulation of serine-type peptidase activity [GO:1902572]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]	adult behavior [GO:0030534]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; learning [GO:0007612]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuromuscular process controlling balance [GO:0050885]; neurotransmitter secretion [GO:0007269]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein heterotetramerization [GO:0051290]; regulation of grooming behavior [GO:2000821]; synapse assembly [GO:0007416]; vesicle docking involved in exocytosis [GO:0006904]	actin cytoskeleton reorganization [GO:0031532]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; filopodium assembly [GO:0046847]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; negative regulation of neuron projection development [GO:0010977]; negative regulation of serine-type peptidase activity [GO:1902572]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; neuron cell-cell adhesion [GO:0007158]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor clustering [GO:0043113]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]	cell junction [GO:0030054]; cell projection [GO:0042995]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; vesicle [GO:0031982]	axon [GO:0030424]; basal part of cell [GO:0045178]; basement membrane [GO:0005604]; cell junction [GO:0030054]; extracellular matrix [GO:0031012]; extracellular matrix of synaptic cleft [GO:0098965]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; photoreceptor ribbon synapse [GO:0098684]; plasma membrane [GO:0005886]; synapse [GO:0045202]	acetylcholine receptor binding [GO:0033130]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]	acetylcholine receptor regulator activity [GO:0030548]; calcium ion binding [GO:0005509]; chondroitin sulfate binding [GO:0035374]; dystroglycan binding [GO:0002162]; extracellular matrix binding [GO:0050840]; glycosaminoglycan binding [GO:0005539]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; laminin-1 binding [GO:0043237]; laminin binding [GO:0043236]; serine-type endopeptidase inhibitor activity [GO:0004867]; sialic acid binding [GO:0033691]; signaling receptor activity [GO:0038023]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]
d3bj2a__d3fh9a___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3bj3a__d5jggb___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3bj3c__d3lhbh___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3bj911_d4q74a2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3bjga__d2q8wa___1		Viridiplantae		Streptophyta		rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]				rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3bjkc__d4a0yb___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; acyl-CoA hydrolase activity [GO:0047617]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]; acyl-CoA metabolic process [GO:0006637]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of transcription, DNA-templated [GO:0045892]	acyl-CoA metabolic process [GO:0006637]	fatty acid biosynthetic process [GO:0006633]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]		acyl-CoA hydrolase activity [GO:0047617]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]
d3bjke__d4i83e___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acyl-CoA hydrolase activity [GO:0047617]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]; acyl-CoA metabolic process [GO:0006637]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	acyl-CoA metabolic process [GO:0006637]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	acyl-CoA hydrolase activity [GO:0047617]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3bjla1_d4jfya2__1												
d3bjla2_d3utze2__1												
d3bjlb1_d5dhxl1__1						host cell cytoplasm [GO:0030430]; host cell nucleolus [GO:0044196]; DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]; mRNA transport [GO:0051028]; viral process [GO:0016032]		mRNA transport [GO:0051028]; viral process [GO:0016032]		host cell cytoplasm [GO:0030430]; host cell nucleolus [GO:0044196]		DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]
d3bjlb2_d1ngwa2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3bjlb2_d3u4bl1__1												
d3bjpa1_d4n3ma2__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d3bjub1_d1o7ia___1	Metazoa		Chordata	Crenarchaeota	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]; activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	DNA binding [GO:0003677]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle checkpoint [GO:0007093]; response to ionizing radiation [GO:0010212]	activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle checkpoint [GO:0007093]; response to ionizing radiation [GO:0010212]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]	DNA binding [GO:0003677]
d3bjud2_d1kogg2__1	Metazoa		Chordata	Proteobacteria	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]; activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	activation of MAPK activity [GO:0000187]; basophil activation involved in immune response [GO:0002276]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERK1 and ERK2 cascade [GO:0070371]; lysyl-tRNA aminoacylation [GO:0006430]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of metallopeptidase activity [GO:1905050]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of transcription, DNA-templated [GO:0045893]; response to X-ray [GO:0010165]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ATP adenylyltransferase activity [GO:0003877]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; lysine-tRNA ligase activity [GO:0004824]; protein homodimerization activity [GO:0042803]; tRNA binding [GO:0000049]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d3bk8a1_d1nbub___1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]
d3bk9g__d2nw8a___1			Proteobacteria	Proteobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; tryptophan 2,3-dioxygenase activity [GO:0004833]; protein homotetramerization [GO:0051289]; tryptophan catabolic process to acetyl-CoA [GO:0019442]; tryptophan catabolic process to kynurenine [GO:0019441]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; tryptophan 2,3-dioxygenase activity [GO:0004833]; protein homotetramerization [GO:0051289]; tryptophan catabolic process to acetyl-CoA [GO:0019442]; tryptophan catabolic process to kynurenine [GO:0019441]	protein homotetramerization [GO:0051289]; tryptophan catabolic process to acetyl-CoA [GO:0019442]; tryptophan catabolic process to kynurenine [GO:0019441]	protein homotetramerization [GO:0051289]; tryptophan catabolic process to acetyl-CoA [GO:0019442]; tryptophan catabolic process to kynurenine [GO:0019441]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; tryptophan 2,3-dioxygenase activity [GO:0004833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; tryptophan 2,3-dioxygenase activity [GO:0004833]
d3bkcl2_d5ovwh___1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; cobalamin binding [GO:0031419]; cobalamin transport [GO:0015889]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cobalamin transport [GO:0015889]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cobalamin binding [GO:0031419]
d3bkic__d1bp5a___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d3bkid__d4n15a___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d3bkip__d1b3ha___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	protein transport [GO:0015031]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	peptide transmembrane transporter activity [GO:1904680]
d3bkip__d2bjjx2__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d3bkml1_d3revb2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3bkna__d4tods___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3bknb__d1nf6d___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3bknc__d2z6mf___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3bknd__d1w69a___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]	cell [GO:0005623]	cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3bkne__d1z4ad___1			Actinobacteria	Thermotogae	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3bknf__d3wvua___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3bkng__d1f30j___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3bkni__d3ak8a___1			Actinobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	
d3bknk__d4zttc___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3bkqx3_d1lxta2__1		Metazoa	Proteobacteria	Chordata	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	glucose metabolic process [GO:0006006]		sarcoplasmic reticulum [GO:0016529]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d3bkqx4_d1jdya4__1		Metazoa	Proteobacteria	Chordata	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	glucose metabolic process [GO:0006006]		sarcoplasmic reticulum [GO:0016529]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d3bkra__d2ksia___1	Metazoa	Metazoa	Arthropoda	Arthropoda								
d3bksa__d2c0lb___1	Metazoa	Metazoa	Arthropoda	Chordata		cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; cholesterol binding [GO:0015485]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]; oleic acid binding [GO:0070538]; phosphatidylinositol transfer activity [GO:0008526]; propanoyl-CoA C-acyltransferase activity [GO:0033814]; propionyl-CoA C2-trimethyltridecanoyltransferase activity [GO:0050632]; signaling receptor binding [GO:0005102]; alpha-linolenic acid metabolic process [GO:0036109]; bile acid biosynthetic process [GO:0006699]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid hydroperoxide transport [GO:1901373]; phospholipid transport [GO:0015914]; positive regulation of intracellular cholesterol transport [GO:0032385]; positive regulation of steroid metabolic process [GO:0045940]; progesterone biosynthetic process [GO:0006701]; protein localization to plasma membrane [GO:0072659]; protein targeting to peroxisome [GO:0006625]; steroid biosynthetic process [GO:0006694]		alpha-linolenic acid metabolic process [GO:0036109]; bile acid biosynthetic process [GO:0006699]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid hydroperoxide transport [GO:1901373]; phospholipid transport [GO:0015914]; positive regulation of intracellular cholesterol transport [GO:0032385]; positive regulation of steroid metabolic process [GO:0045940]; progesterone biosynthetic process [GO:0006701]; protein localization to plasma membrane [GO:0072659]; protein targeting to peroxisome [GO:0006625]; steroid biosynthetic process [GO:0006694]		cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]		cholesterol binding [GO:0015485]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]; oleic acid binding [GO:0070538]; phosphatidylinositol transfer activity [GO:0008526]; propanoyl-CoA C-acyltransferase activity [GO:0033814]; propionyl-CoA C2-trimethyltridecanoyltransferase activity [GO:0050632]; signaling receptor binding [GO:0005102]
d3bktb__d3dhxb2__1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; protein homotetramerization [GO:0051289]; response to nickel cation [GO:0010045]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; Gram-negative-bacterium-type cell wall [GO:0009276]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATPase-coupled transmembrane transporter activity [GO:0042626]; D-methionine transmembrane transporter activity [GO:0048474]; L-methionine transmembrane transporter activity [GO:0015191]; D-methionine transport [GO:0048473]	negative regulation of DNA-templated transcription, initiation [GO:2000143]; protein homotetramerization [GO:0051289]; response to nickel cation [GO:0010045]	D-methionine transport [GO:0048473]	protein-DNA complex [GO:0032993]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; Gram-negative-bacterium-type cell wall [GO:0009276]	bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; D-methionine transmembrane transporter activity [GO:0048474]; L-methionine transmembrane transporter activity [GO:0015191]
d3bkuc__d3lghc___1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; protein homotetramerization [GO:0051289]; response to nickel cation [GO:0010045]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	negative regulation of DNA-templated transcription, initiation [GO:2000143]; protein homotetramerization [GO:0051289]; response to nickel cation [GO:0010045]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	protein-DNA complex [GO:0032993]	protein-DNA complex [GO:0032993]	bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3blba3_d4m1bb___1	Metazoa		Arthropoda	Firmicutes	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]
d3blhb2_d1find2__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d3blka1_d1bg4a___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d3blka2_d1gjwa1__1	Metazoa		Chordata	Thermotogae	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	transferase activity [GO:0016740]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	transferase activity [GO:0016740]
d3blpx2_d1j0ja2__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d3blqb1_d1o9kf___1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]; androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d3blrb2_d1tfba1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3blua__d2h4ga___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	pathogenesis [GO:0009405]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	extracellular region [GO:0005576]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3bm5a1_d1z7wa1__1		Viridiplantae		Streptophyta	cysteine synthase activity [GO:0004124]; cysteine biosynthetic process from serine [GO:0006535]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; cysteine synthase activity [GO:0004124]; pyridoxal phosphate binding [GO:0030170]; aging [GO:0007568]; cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process from serine [GO:0006535]; double fertilization forming a zygote and endosperm [GO:0009567]; pollen tube growth [GO:0009860]; response to cadmium ion [GO:0046686]	cysteine biosynthetic process from serine [GO:0006535]	aging [GO:0007568]; cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process from serine [GO:0006535]; double fertilization forming a zygote and endosperm [GO:0009567]; pollen tube growth [GO:0009860]; response to cadmium ion [GO:0046686]		apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]	cysteine synthase activity [GO:0004124]	cysteine synthase activity [GO:0004124]; pyridoxal phosphate binding [GO:0030170]
d3bm5b__d1pwhc___1		Metazoa		Chordata	cysteine synthase activity [GO:0004124]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]; gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]	cysteine biosynthetic process from serine [GO:0006535]	gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]		cytoplasm [GO:0005737]	cysteine synthase activity [GO:0004124]	L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]
d3bmva1_d4alra___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; chitin binding [GO:0008061]; copper ion binding [GO:0005507]; monooxygenase activity [GO:0004497]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	chitin binding [GO:0008061]; copper ion binding [GO:0005507]; monooxygenase activity [GO:0004497]
d3bmva3_d1ji1b2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d3bmwa4_d1jf5b3__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d3bn3b1_d5yaxb2__1	Metazoa		Chordata		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; extracellular matrix organization [GO:0030198]; phagocytosis [GO:0006909]; regulation of immune response [GO:0050776]	integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; extracellular matrix organization [GO:0030198]; phagocytosis [GO:0006909]; regulation of immune response [GO:0050776]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	integrin binding [GO:0005178]	
d3bn3b2_d2iqaa1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; extracellular matrix organization [GO:0030198]; phagocytosis [GO:0006909]; regulation of immune response [GO:0050776]	metal ion binding [GO:0046872]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; extracellular matrix organization [GO:0030198]; phagocytosis [GO:0006909]; regulation of immune response [GO:0050776]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		integrin binding [GO:0005178]	metal ion binding [GO:0046872]
d3bn4c__d3i6pf___1			Cyanobacteria	Proteobacteria		ethanolamine degradation polyhedral organelle [GO:0031471]; structural molecule activity [GO:0005198]; ethanolamine catabolic process [GO:0046336]		ethanolamine catabolic process [GO:0046336]		ethanolamine degradation polyhedral organelle [GO:0031471]		structural molecule activity [GO:0005198]
d3bn4d__d4qivc___1			Cyanobacteria	Proteobacteria								
d3bn4e__d4p2sc___1			Cyanobacteria									
d3bn4f__d5djbg___1			Cyanobacteria	Proteobacteria								
d3bn6a__d1w9fa___1	Metazoa	Fungi	Chordata	Chytridiomycota	extracellular region [GO:0005576]; membrane [GO:0016020]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338]		angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; single fertilization [GO:0007338]		extracellular region [GO:0005576]; membrane [GO:0016020]			
d3bn9a__d2wv5c___1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3bn9c1_d5ijvc1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3bnea1_d3v98a2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]; oxylipin biosynthetic process [GO:0031408]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nuclear envelope [GO:0005635]; nuclear envelope lumen [GO:0005641]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]; arachidonate 5-lipoxygenase activity [GO:0004051]; iron ion binding [GO:0005506]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-18-mediated signaling pathway [GO:0035655]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]	oxylipin biosynthetic process [GO:0031408]	cytokine-mediated signaling pathway [GO:0019221]; interleukin-18-mediated signaling pathway [GO:0035655]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nuclear envelope [GO:0005635]; nuclear envelope lumen [GO:0005641]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]	linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]	arachidonate 5-lipoxygenase activity [GO:0004051]; iron ion binding [GO:0005506]
d3bnga__d1qdba___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]; nitrate assimilation [GO:0042128]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]; nitrate assimilation [GO:0042128]	nitrate assimilation [GO:0042128]; nitrogen compound metabolic process [GO:0006807]	nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]	calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]	calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]
d3bo2a1_d4ed5b1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d3bo4a1_d2mzqa1__1	Metazoa	Fungi	Chordata	Ascomycota	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleus [GO:0005634]; post-mRNA release spliceosomal complex [GO:0071014]; ribonucleoprotein complex [GO:1990904]; chromatin binding [GO:0003682]; mRNA binding [GO:0003729]; single-stranded telomeric DNA binding [GO:0043047]; nuclear mRNA surveillance [GO:0071028]; poly(A)+ mRNA export from nucleus [GO:0016973]; regulation of mRNA stability involved in response to oxidative stress [GO:2000815]; telomere maintenance [GO:0000723]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	nuclear mRNA surveillance [GO:0071028]; poly(A)+ mRNA export from nucleus [GO:0016973]; regulation of mRNA stability involved in response to oxidative stress [GO:2000815]; telomere maintenance [GO:0000723]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleus [GO:0005634]; post-mRNA release spliceosomal complex [GO:0071014]; ribonucleoprotein complex [GO:1990904]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	chromatin binding [GO:0003682]; mRNA binding [GO:0003729]; single-stranded telomeric DNA binding [GO:0043047]
d3bo8b1_d4m9oa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3boca__d3uk8b___1			Bacillariophyta (diatoms)	Bacillariophyta (diatoms)	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3boma__d2vmlj___1	Metazoa		Chordata	Cyanobacteria	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3boma__d5eoha___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]		apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]	hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3bomd__d1yhum___1	Metazoa	Metazoa	Chordata	Annelida	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3bowb__d5d69a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; proteolysis [GO:0006508]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	proteolysis [GO:0006508]	cornification [GO:0070268]; extracellular matrix disassembly [GO:0022617]; positive regulation of cell population proliferation [GO:0008284]; regulation of macroautophagy [GO:0016241]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d3bp9s__d2wlva___1					host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral budding via host ESCRT complex [GO:0039702]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; viral budding via host ESCRT complex [GO:0039702]	viral budding via host ESCRT complex [GO:0039702]	viral budding via host ESCRT complex [GO:0039702]	host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; membrane [GO:0016020]; viral nucleocapsid [GO:0019013]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	RNA binding [GO:0003723]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3bpca1_d4enee1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3bpca1_d4lcwg1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3bplb1_d6b24d___1	Metazoa		Chordata	Proteobacteria	centriolar satellite [GO:0034451]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; interleukin-4 receptor activity [GO:0004913]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; immune response [GO:0006955]; immunoglobulin mediated immune response [GO:0016064]; negative regulation of T-helper 1 cell differentiation [GO:0045626]; ovulation [GO:0030728]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; production of molecular mediator involved in inflammatory response [GO:0002532]; regulation of cell population proliferation [GO:0042127]; response to estrogen [GO:0043627]; response to odorant [GO:1990834]; signal transduction [GO:0007165]	integral component of plasma membrane [GO:0005887]; inorganic anion transmembrane transporter activity [GO:0015103]	cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; immune response [GO:0006955]; immunoglobulin mediated immune response [GO:0016064]; negative regulation of T-helper 1 cell differentiation [GO:0045626]; ovulation [GO:0030728]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; production of molecular mediator involved in inflammatory response [GO:0002532]; regulation of cell population proliferation [GO:0042127]; response to estrogen [GO:0043627]; response to odorant [GO:1990834]; signal transduction [GO:0007165]		centriolar satellite [GO:0034451]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	integral component of plasma membrane [GO:0005887]	interleukin-4 receptor activity [GO:0004913]	inorganic anion transmembrane transporter activity [GO:0015103]
d3bpob2_d2edya1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; interleukin-13 receptor complex [GO:0005898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-2 binding [GO:0019976]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]	extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; chondroitin sulfate proteoglycan binding [GO:0035373]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; protein-containing complex binding [GO:0044877]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]	cell adhesion [GO:0007155]; cell migration [GO:0016477]; negative regulation of receptor binding [GO:1900121]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]	external side of plasma membrane [GO:0009897]; interleukin-13 receptor complex [GO:0005898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-2 binding [GO:0019976]	cell adhesion molecule binding [GO:0050839]; chondroitin sulfate proteoglycan binding [GO:0035373]; heparin binding [GO:0008201]; protein-containing complex binding [GO:0044877]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d3bpwb1_d3f4wa___1			Apicomplexa	Proteobacteria	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; hexulose-6-phosphate synthase activity [GO:0043801]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; hexulose-6-phosphate synthase activity [GO:0043801]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3bpya__d4avpc___1		Metazoa		Chordata		nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; axon guidance [GO:0007411]; cell differentiation [GO:0030154]; mechanosensory behavior [GO:0007638]; muscle organ development [GO:0007517]; peripheral nervous system neuron development [GO:0048935]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]		axon guidance [GO:0007411]; cell differentiation [GO:0030154]; mechanosensory behavior [GO:0007638]; muscle organ development [GO:0007517]; peripheral nervous system neuron development [GO:0048935]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]		nuclear chromatin [GO:0000790]; nucleus [GO:0005634]		DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d3bpzb__d3i54d1__1	Metazoa		Chordata	Actinobacteria	axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; molecular adaptor activity [GO:0060090]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; molecular adaptor activity [GO:0060090]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3bpzd__d3rypa1__1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; molecular adaptor activity [GO:0060090]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; molecular adaptor activity [GO:0060090]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3bq0a1_d1rysb1__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d3bq2a1_d1pm0a2__1			Crenarchaeota		cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]		DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]		damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	
d3bq2a1_d2c2da1__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d3bq4e__d2j2jc___1					viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	viral capsid [GO:0019028]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]		
d3bq7b__d4pznb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; diacylglycerol binding [GO:0019992]; diacylglycerol kinase activity [GO:0004143]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD+ kinase activity [GO:0003951]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; diacylglycerol metabolic process [GO:0046339]; endocytosis [GO:0006897]; epidermal growth factor receptor signaling pathway [GO:0007173]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; multicellular organism development [GO:0007275]; platelet activation [GO:0030168]; protein homooligomerization [GO:0051260]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein transport [GO:0015031]; response to organic substance [GO:0010033]; second-messenger-mediated signaling [GO:0019932]; signal transduction [GO:0007165]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519]; PRC1 complex [GO:0035102]; DNA binding [GO:0003677]; zinc ion binding [GO:0008270]; multicellular organism development [GO:0007275]; negative regulation of G0 to G1 transition [GO:0070317]	diacylglycerol metabolic process [GO:0046339]; endocytosis [GO:0006897]; epidermal growth factor receptor signaling pathway [GO:0007173]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; multicellular organism development [GO:0007275]; platelet activation [GO:0030168]; protein homooligomerization [GO:0051260]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein transport [GO:0015031]; response to organic substance [GO:0010033]; second-messenger-mediated signaling [GO:0019932]; signal transduction [GO:0007165]	multicellular organism development [GO:0007275]; negative regulation of G0 to G1 transition [GO:0070317]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PcG protein complex [GO:0031519]; PRC1 complex [GO:0035102]	ATP binding [GO:0005524]; diacylglycerol binding [GO:0019992]; diacylglycerol kinase activity [GO:0004143]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD+ kinase activity [GO:0003951]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	DNA binding [GO:0003677]; zinc ion binding [GO:0008270]
d3bq7c1_d5j8ya1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; diacylglycerol binding [GO:0019992]; diacylglycerol kinase activity [GO:0004143]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD+ kinase activity [GO:0003951]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; diacylglycerol metabolic process [GO:0046339]; endocytosis [GO:0006897]; epidermal growth factor receptor signaling pathway [GO:0007173]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; multicellular organism development [GO:0007275]; platelet activation [GO:0030168]; protein homooligomerization [GO:0051260]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein transport [GO:0015031]; response to organic substance [GO:0010033]; second-messenger-mediated signaling [GO:0019932]; signal transduction [GO:0007165]	nucleus [GO:0005634]; polytene chromosome [GO:0005700]; PRC1 complex [GO:0035102]; identical protein binding [GO:0042802]; PRC1 complex binding [GO:0140259]; zinc ion binding [GO:0008270]; axonogenesis [GO:0007409]; chromatin organization [GO:0006325]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; ventral cord development [GO:0007419]	diacylglycerol metabolic process [GO:0046339]; endocytosis [GO:0006897]; epidermal growth factor receptor signaling pathway [GO:0007173]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; multicellular organism development [GO:0007275]; platelet activation [GO:0030168]; protein homooligomerization [GO:0051260]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein transport [GO:0015031]; response to organic substance [GO:0010033]; second-messenger-mediated signaling [GO:0019932]; signal transduction [GO:0007165]	axonogenesis [GO:0007409]; chromatin organization [GO:0006325]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; ventral cord development [GO:0007419]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	nucleus [GO:0005634]; polytene chromosome [GO:0005700]; PRC1 complex [GO:0035102]	ATP binding [GO:0005524]; diacylglycerol binding [GO:0019992]; diacylglycerol kinase activity [GO:0004143]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD+ kinase activity [GO:0003951]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; PRC1 complex binding [GO:0140259]; zinc ion binding [GO:0008270]
d3bqmb__d1yvpa2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; misfolded RNA binding [GO:0034336]; cell projection organization [GO:0030030]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cell projection organization [GO:0030030]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	cytoplasm [GO:0005737]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	metal ion binding [GO:0046872]; misfolded RNA binding [GO:0034336]
d3bqnb__d2nvoa1__1	Metazoa		Chordata	Deinococcus-Thermus	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3bqqa__d1m12a1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule membrane [GO:0035577]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; beta-galactosidase activity [GO:0004565]; enzyme activator activity [GO:0008047]; G protein-coupled receptor binding [GO:0001664]; ganglioside GM1 binding [GO:1905573]; ganglioside GM2 binding [GO:1905574]; ganglioside GM3 binding [GO:1905575]; ganglioside GP1c binding [GO:1905577]; ganglioside GT1b binding [GO:1905576]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; cochlea development [GO:0090102]; corneocyte development [GO:0003335]; cornified envelope assembly [GO:1903575]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; G protein-coupled receptor signaling pathway [GO:0007186]; galactosylceramide catabolic process [GO:0006683]; ganglioside GM1 transport to membrane [GO:1905572]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; micturition [GO:0060073]; myelination [GO:0042552]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]; sensory perception of sound [GO:0007605]; walking behavior [GO:0090659]	azurophil granule membrane [GO:0035577]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; beta-galactosidase activity [GO:0004565]; enzyme activator activity [GO:0008047]; G protein-coupled receptor binding [GO:0001664]; ganglioside GM1 binding [GO:1905573]; ganglioside GM2 binding [GO:1905574]; ganglioside GM3 binding [GO:1905575]; ganglioside GP1c binding [GO:1905577]; ganglioside GT1b binding [GO:1905576]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; cochlea development [GO:0090102]; corneocyte development [GO:0003335]; cornified envelope assembly [GO:1903575]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; G protein-coupled receptor signaling pathway [GO:0007186]; galactosylceramide catabolic process [GO:0006683]; ganglioside GM1 transport to membrane [GO:1905572]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; micturition [GO:0060073]; myelination [GO:0042552]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]; sensory perception of sound [GO:0007605]; walking behavior [GO:0090659]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; cochlea development [GO:0090102]; corneocyte development [GO:0003335]; cornified envelope assembly [GO:1903575]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; galactosylceramide catabolic process [GO:0006683]; ganglioside GM1 transport to membrane [GO:1905572]; glycosphingolipid metabolic process [GO:0006687]; G protein-coupled receptor signaling pathway [GO:0007186]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; micturition [GO:0060073]; myelination [GO:0042552]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]; sensory perception of sound [GO:0007605]; walking behavior [GO:0090659]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; cochlea development [GO:0090102]; corneocyte development [GO:0003335]; cornified envelope assembly [GO:1903575]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; galactosylceramide catabolic process [GO:0006683]; ganglioside GM1 transport to membrane [GO:1905572]; glycosphingolipid metabolic process [GO:0006687]; G protein-coupled receptor signaling pathway [GO:0007186]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; micturition [GO:0060073]; myelination [GO:0042552]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; platelet degranulation [GO:0002576]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]; sensory perception of sound [GO:0007605]; walking behavior [GO:0090659]	azurophil granule membrane [GO:0035577]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886]	azurophil granule membrane [GO:0035577]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; plasma membrane [GO:0005886]	beta-galactosidase activity [GO:0004565]; enzyme activator activity [GO:0008047]; ganglioside GM1 binding [GO:1905573]; ganglioside GM2 binding [GO:1905574]; ganglioside GM3 binding [GO:1905575]; ganglioside GP1c binding [GO:1905577]; ganglioside GT1b binding [GO:1905576]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	beta-galactosidase activity [GO:0004565]; enzyme activator activity [GO:0008047]; ganglioside GM1 binding [GO:1905573]; ganglioside GM2 binding [GO:1905574]; ganglioside GM3 binding [GO:1905575]; ganglioside GP1c binding [GO:1905577]; ganglioside GT1b binding [GO:1905576]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; phospholipid binding [GO:0005543]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d3bqva__d4g70b2__1			Cyanobacteria	Deinococcus-Thermus	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]			thylakoid membrane [GO:0042651]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d3br5d1_d3g1oa1__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d3brda1_d4yeea___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; cell fate specification [GO:0001708]; dauer exit [GO:0043054]; germ-line stem cell division [GO:0042078]; nematode larval development [GO:0002119]; Notch signaling pathway [GO:0007219]; oviposition [GO:0018991]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vulval development [GO:0040026]; regulation of cell fate specification [GO:0042659]	apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]; fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]	cell fate specification [GO:0001708]; dauer exit [GO:0043054]; germ-line stem cell division [GO:0042078]; nematode larval development [GO:0002119]; Notch signaling pathway [GO:0007219]; oviposition [GO:0018991]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vulval development [GO:0040026]; regulation of cell fate specification [GO:0042659]	fatty acid biosynthetic process [GO:0006633]; positive regulation of cold-induced thermogenesis [GO:0120162]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	apical plasma membrane [GO:0016324]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]	enzyme binding [GO:0019899]; protein kinase binding [GO:0019901]
d3bria__d1re6a1__1	Metazoa	Metazoa	Arthropoda	Chordata	cell [GO:0005623]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]; disordered domain specific binding [GO:0097718]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein homodimerization activity [GO:0042803]; actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; oogenesis [GO:0048477]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; sperm individualization [GO:0007291]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; wing disc development [GO:0035220]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; glutamatergic synapse [GO:0098978]; microtubule [GO:0005874]; myosin V complex [GO:0031475]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; microtubule-based process [GO:0007017]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]	actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; oogenesis [GO:0048477]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; sperm individualization [GO:0007291]; wing disc development [GO:0035220]	microtubule-based process [GO:0007017]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]	cell [GO:0005623]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; glutamatergic synapse [GO:0098978]; microtubule [GO:0005874]; myosin V complex [GO:0031475]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]	disordered domain specific binding [GO:0097718]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein homodimerization activity [GO:0042803]	dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]
d3brla__d3dvhb___1	Metazoa	Metazoa	Arthropoda	Arthropoda	cell [GO:0005623]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]; disordered domain specific binding [GO:0097718]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein homodimerization activity [GO:0042803]; actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; oogenesis [GO:0048477]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; sperm individualization [GO:0007291]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; wing disc development [GO:0035220]	cell [GO:0005623]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]; disordered domain specific binding [GO:0097718]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein homodimerization activity [GO:0042803]; actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; oogenesis [GO:0048477]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; sperm individualization [GO:0007291]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; wing disc development [GO:0035220]	actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; oogenesis [GO:0048477]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; sperm individualization [GO:0007291]; wing disc development [GO:0035220]	actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; oogenesis [GO:0048477]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; sperm individualization [GO:0007291]; wing disc development [GO:0035220]	cell [GO:0005623]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]	cell [GO:0005623]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]	disordered domain specific binding [GO:0097718]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein homodimerization activity [GO:0042803]	disordered domain specific binding [GO:0097718]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein homodimerization activity [GO:0042803]
d3bs8a__d1kl1a___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	protoporphyrinogen IX biosynthetic process [GO:0006782]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]
d3bsga2_d3muab___1	Viridiplantae		Streptophyta	Firmicutes	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	endo-1,4-beta-xylanase activity [GO:0031176]
d3bsmd1_d5eu9b1__1		Metazoa	Proteobacteria	Chordata	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3bsqc1_d1c4y.1__1	Metazoa	Metazoa	Chordata	Chordata	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d3btaa1_d1g9ca1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d3btaa1_d1jyib___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]		metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3btaa2_d5fzza___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	endopeptidase inhibitor activity [GO:0004866]; peptidase activity [GO:0008233]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]		metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	endopeptidase inhibitor activity [GO:0004866]; peptidase activity [GO:0008233]
d3btcb1_d1rpwc1__1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3btcd1_d1jtye1__1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3btfe__d1l1nb___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3btib1_d3btce1__1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3btid2_d5gpab2__1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	DNA binding [GO:0003677]	negative regulation of transcription, DNA-templated [GO:0045892]				DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d3btid2_d5myla2__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d3btie1_d4jykb1__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	protein-DNA complex [GO:0032993]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]		protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3btjd1_d3whcb1__1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; fatty acid metabolic process [GO:0006631]; lipid catabolic process [GO:0016042]	negative regulation of transcription, DNA-templated [GO:0045892]	fatty acid metabolic process [GO:0006631]; lipid catabolic process [GO:0016042]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d3btje1_d4m3ba1__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d3btoa2_d4kuhc1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]
d3btoc2_d4bhte2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	glutamate biosynthetic process [GO:0006537]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]
d3btod2_d1bxzd2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]
d3buab__d5xupa___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; 5'-3' exodeoxyribonuclease activity [GO:0035312]; 5'-3' exonuclease activity [GO:0008409]; damaged DNA binding [GO:0003684]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; mitotic cell cycle checkpoint [GO:0007093]; protection from non-homologous end joining at telomere [GO:0031848]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833]; telomeric 3' overhang formation [GO:0031860]; telomeric loop formation [GO:0031627]	cell [GO:0005623]; chromosome, telomeric region [GO:0000781]; nuclear chromosome, telomeric region [GO:0000784]; nuclear inner membrane [GO:0005637]; shelterin complex [GO:0070187]; DNA binding [GO:0003677]; meiotic attachment of telomere to nuclear envelope [GO:0070197]; meiotic telomere clustering [GO:0045141]; synapsis [GO:0007129]	double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; mitotic cell cycle checkpoint [GO:0007093]; protection from non-homologous end joining at telomere [GO:0031848]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833]; telomeric 3' overhang formation [GO:0031860]; telomeric loop formation [GO:0031627]	meiotic attachment of telomere to nuclear envelope [GO:0070197]; meiotic telomere clustering [GO:0045141]; synapsis [GO:0007129]	centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]	cell [GO:0005623]; chromosome, telomeric region [GO:0000781]; nuclear chromosome, telomeric region [GO:0000784]; nuclear inner membrane [GO:0005637]; shelterin complex [GO:0070187]	5'-3' exodeoxyribonuclease activity [GO:0035312]; 5'-3' exonuclease activity [GO:0008409]; damaged DNA binding [GO:0003684]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]	DNA binding [GO:0003677]
d3buda2_d1jynd4__1	Metazoa		Arthropoda	Proteobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	beta-galactosidase complex [GO:0009341]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3buda3_d3dx2a1__1	Metazoa	Metazoa	Arthropoda	Arthropoda	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d3buec__d1b4ab2__1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3buee__d1xxbe___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]
d3buef__d1f9ne2__1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3buia3_d2f7ra3__1	Metazoa	Metazoa	Arthropoda	Arthropoda	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d3bula2_d4reqa2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cobalamin binding [GO:0031419]; methionine synthase activity [GO:0008705]; protein methyltransferase activity [GO:0008276]; zinc ion binding [GO:0008270]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		cobalamin binding [GO:0031419]; methionine synthase activity [GO:0008705]; protein methyltransferase activity [GO:0008276]; zinc ion binding [GO:0008270]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d3bumb1_d1mhoa___1	Metazoa	Metazoa	Chordata	Chordata	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d3bunb1_d1df0b___1	Metazoa	Metazoa	Chordata	Chordata	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; proteolysis [GO:0006508]	cell surface receptor signaling pathway [GO:0007166]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; interleukin-6-mediated signaling pathway [GO:0070102]; male gonad development [GO:0008584]; mast cell degranulation [GO:0043303]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron death [GO:1901215]; neuron death [GO:0070997]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; regulation of Rap protein signal transduction [GO:0032487]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to starvation [GO:0042594]; response to testosterone [GO:0033574]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	proteolysis [GO:0006508]	cilium [GO:0005929]; cytosol [GO:0005829]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; mast cell granule [GO:0042629]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]
d3bupa2_d1mmzb1__1	Metazoa		Arthropoda	Firmicutes	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	galactose metabolic process [GO:0006012]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d3buqa1_d1k1xb1__1	Metazoa		Arthropoda	Euryarchaeota	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]
d3buwb1_d1qasa1__1	Metazoa	Metazoa	Chordata	Chordata	B cell receptor complex [GO:0019815]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early phagosome [GO:0032009]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T cell receptor complex [GO:0042101]; ATP binding [GO:0005524]; integrin binding [GO:0005178]; interleukin-15 receptor binding [GO:0016170]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatase binding [GO:0019902]; phosphotyrosine residue binding [GO:0001784]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; Toll-like receptor binding [GO:0035325]; activation of JUN kinase activity [GO:0007257]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; B cell receptor signaling pathway [GO:0050853]; beta selection [GO:0043366]; blood vessel morphogenesis [GO:0048514]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to molecule of fungal origin [GO:0071226]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; interleukin-3-mediated signaling pathway [GO:0038156]; leukocyte activation involved in immune response [GO:0002366]; leukocyte cell-cell adhesion [GO:0007159]; leukotriene biosynthetic process [GO:0019370]; lymph vessel development [GO:0001945]; macrophage activation involved in immune response [GO:0002281]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine phosphorylation [GO:0018105]; platelet activation [GO:0030168]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of bone resorption [GO:0045780]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0045425]; positive regulation of interleukin-10 biosynthetic process [GO:0045082]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of interleukin-3 biosynthetic process [GO:0045401]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of receptor internalization [GO:0002092]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of type I interferon production [GO:0032481]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; receptor internalization [GO:0031623]; regulation of arachidonic acid secretion [GO:0090237]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neutrophil degranulation [GO:0043313]; regulation of phagocytosis [GO:0050764]; regulation of platelet activation [GO:0010543]; regulation of platelet aggregation [GO:0090330]; regulation of superoxide anion generation [GO:0032928]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; serotonin secretion by platelet [GO:0002554]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral process [GO:0016032]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	activation of JUN kinase activity [GO:0007257]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; B cell receptor signaling pathway [GO:0050853]; beta selection [GO:0043366]; blood vessel morphogenesis [GO:0048514]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to molecule of fungal origin [GO:0071226]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; interleukin-3-mediated signaling pathway [GO:0038156]; leukocyte activation involved in immune response [GO:0002366]; leukocyte cell-cell adhesion [GO:0007159]; leukotriene biosynthetic process [GO:0019370]; lymph vessel development [GO:0001945]; macrophage activation involved in immune response [GO:0002281]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine phosphorylation [GO:0018105]; platelet activation [GO:0030168]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of bone resorption [GO:0045780]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0045425]; positive regulation of interleukin-10 biosynthetic process [GO:0045082]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of interleukin-3 biosynthetic process [GO:0045401]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of receptor internalization [GO:0002092]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of type I interferon production [GO:0032481]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; receptor internalization [GO:0031623]; regulation of arachidonic acid secretion [GO:0090237]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neutrophil degranulation [GO:0043313]; regulation of phagocytosis [GO:0050764]; regulation of platelet activation [GO:0010543]; regulation of platelet aggregation [GO:0090330]; regulation of superoxide anion generation [GO:0032928]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; serotonin secretion by platelet [GO:0002554]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral process [GO:0016032]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	B cell receptor complex [GO:0019815]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early phagosome [GO:0032009]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T cell receptor complex [GO:0042101]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	ATP binding [GO:0005524]; integrin binding [GO:0005178]; interleukin-15 receptor binding [GO:0016170]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatase binding [GO:0019902]; phosphotyrosine residue binding [GO:0001784]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; Toll-like receptor binding [GO:0035325]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]
d3buwd1_d4byaa1__1	Metazoa	Metazoa	Chordata	Chordata	B cell receptor complex [GO:0019815]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early phagosome [GO:0032009]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T cell receptor complex [GO:0042101]; ATP binding [GO:0005524]; integrin binding [GO:0005178]; interleukin-15 receptor binding [GO:0016170]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatase binding [GO:0019902]; phosphotyrosine residue binding [GO:0001784]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; Toll-like receptor binding [GO:0035325]; activation of JUN kinase activity [GO:0007257]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; B cell receptor signaling pathway [GO:0050853]; beta selection [GO:0043366]; blood vessel morphogenesis [GO:0048514]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to molecule of fungal origin [GO:0071226]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; interleukin-3-mediated signaling pathway [GO:0038156]; leukocyte activation involved in immune response [GO:0002366]; leukocyte cell-cell adhesion [GO:0007159]; leukotriene biosynthetic process [GO:0019370]; lymph vessel development [GO:0001945]; macrophage activation involved in immune response [GO:0002281]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine phosphorylation [GO:0018105]; platelet activation [GO:0030168]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of bone resorption [GO:0045780]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0045425]; positive regulation of interleukin-10 biosynthetic process [GO:0045082]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of interleukin-3 biosynthetic process [GO:0045401]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of receptor internalization [GO:0002092]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of type I interferon production [GO:0032481]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; receptor internalization [GO:0031623]; regulation of arachidonic acid secretion [GO:0090237]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neutrophil degranulation [GO:0043313]; regulation of phagocytosis [GO:0050764]; regulation of platelet activation [GO:0010543]; regulation of platelet aggregation [GO:0090330]; regulation of superoxide anion generation [GO:0032928]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; serotonin secretion by platelet [GO:0002554]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral process [GO:0016032]	protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin binding [GO:0017022]; protein C-terminus binding [GO:0008022]; calcium-mediated signaling [GO:0019722]	activation of JUN kinase activity [GO:0007257]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; B cell receptor signaling pathway [GO:0050853]; beta selection [GO:0043366]; blood vessel morphogenesis [GO:0048514]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to molecule of fungal origin [GO:0071226]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; interleukin-3-mediated signaling pathway [GO:0038156]; leukocyte activation involved in immune response [GO:0002366]; leukocyte cell-cell adhesion [GO:0007159]; leukotriene biosynthetic process [GO:0019370]; lymph vessel development [GO:0001945]; macrophage activation involved in immune response [GO:0002281]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine phosphorylation [GO:0018105]; platelet activation [GO:0030168]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of bone resorption [GO:0045780]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0045425]; positive regulation of interleukin-10 biosynthetic process [GO:0045082]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of interleukin-3 biosynthetic process [GO:0045401]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of receptor internalization [GO:0002092]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of type I interferon production [GO:0032481]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein phosphorylation [GO:0006468]; receptor internalization [GO:0031623]; regulation of arachidonic acid secretion [GO:0090237]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neutrophil degranulation [GO:0043313]; regulation of phagocytosis [GO:0050764]; regulation of platelet activation [GO:0010543]; regulation of platelet aggregation [GO:0090330]; regulation of superoxide anion generation [GO:0032928]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; serotonin secretion by platelet [GO:0002554]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral process [GO:0016032]	calcium-mediated signaling [GO:0019722]	B cell receptor complex [GO:0019815]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early phagosome [GO:0032009]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T cell receptor complex [GO:0042101]	protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; integrin binding [GO:0005178]; interleukin-15 receptor binding [GO:0016170]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatase binding [GO:0019902]; phosphotyrosine residue binding [GO:0001784]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; Toll-like receptor binding [GO:0035325]	calcium ion binding [GO:0005509]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin binding [GO:0017022]; protein C-terminus binding [GO:0008022]
d3buya1_d5f97g1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d3buya1_d5wcdl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; immune response [GO:0006955]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d3buza1_d4hhyc2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3buza2_d2j3va2__1	Metazoa		Chordata	Firmicutes	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	pathogenesis [GO:0009405]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	extracellular region [GO:0005576]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	
d3bv7a__d3wg6a___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	2-dehydropantolactone reductase (A-specific) activity [GO:0047011]; cellular ketone metabolic process [GO:0042180]	androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	cellular ketone metabolic process [GO:0042180]	cytosol [GO:0005829]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]	2-dehydropantolactone reductase (A-specific) activity [GO:0047011]
d3bveb1_d3fvbb1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3bved1_d5l8gk1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]
d3bvef1_d5jkmf___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3bvfa1_d1xveb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3bvfb1_d4cybj___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3bvff1_d4toax___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3bvga2_d1bxtb2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d3bvia1_d3rgdm___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3bvib1_d1fz0b___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3bvic1_d3bknh___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3bvke1_d3kx9p___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]
d3bvlc1_d5jklc___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3bvld1_d1nf6e___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3bvld1_d2jd6t___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d3bvlf1_d5mija___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3bvwa2_d3vd4d5__1	Metazoa		Arthropoda	Proteobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	beta-galactosidase complex [GO:0009341]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3bw7a1_d3ax7b5__1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular space [GO:0005615]; cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cytokinin metabolic process [GO:0009690]	xanthine catabolic process [GO:0009115]	extracellular space [GO:0005615]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d3bw9b2_d3g6ah1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3bwaa1_d4trpl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3bwab2_d1vcab1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; amine metabolic process [GO:0009308]; B cell differentiation [GO:0030183]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cardiac neuron differentiation [GO:0060945]; cell adhesion [GO:0007155]; cell-cell adhesion in response to extracellular stimulus [GO:0140039]; cell chemotaxis [GO:0060326]; cell-matrix adhesion [GO:0007160]; cellular response to amyloid-beta [GO:1904646]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chronic inflammatory response [GO:0002544]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; innervation [GO:0060384]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; positive regulation of T cell proliferation [GO:0042102]; regulation of immune response [GO:0050776]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [GO:0071065]; apical part of cell [GO:0045177]; cell surface [GO:0009986]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; podosome [GO:0002102]; sarcolemma [GO:0042383]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; primary amine oxidase activity [GO:0008131]
d3bwab2_d4l8ca2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3bwkb__d1nb5.4__1		Metazoa	Apicomplexa	Chordata	integral component of membrane [GO:0016021]; cysteine-type peptidase activity [GO:0008234]	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]	integral component of membrane [GO:0016021]	cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	cysteine-type peptidase activity [GO:0008234]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]
d3bwqa__d4mj0d___1					capsomere [GO:0046727]; host cell endoplasmic reticulum [GO:0044165]; host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; protein homooligomerization [GO:0051260]; viral capsid assembly [GO:0019069]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; protein homooligomerization [GO:0051260]; viral capsid assembly [GO:0019069]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]	capsomere [GO:0046727]; host cell endoplasmic reticulum [GO:0044165]; host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]	host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d3bwrb__d1cn3e___1					capsomere [GO:0046727]; host cell endoplasmic reticulum [GO:0044165]; host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; protein homooligomerization [GO:0051260]; viral capsid assembly [GO:0019069]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]; structural molecule activity [GO:0005198]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; protein homooligomerization [GO:0051260]; viral capsid assembly [GO:0019069]; virion attachment to host cell [GO:0019062]	caveolin-mediated endocytosis of virus by host cell [GO:0075513]; virion attachment to host cell [GO:0019062]	capsomere [GO:0046727]; host cell endoplasmic reticulum [GO:0044165]; host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]	host cell nucleus [GO:0042025]; T=7 icosahedral viral capsid [GO:0039620]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d3bwya__d5wz2a___1	Metazoa		Chordata		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; methylation [GO:0032259]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; short-term memory [GO:0007614]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; methylation [GO:0032259]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; short-term memory [GO:0007614]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]; orcinol O-methyltransferase activity [GO:0102938]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3bx1d__d2go2a1__1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; sporulation resulting in formation of a cellular spore [GO:0030435]	endopeptidase inhibitor activity [GO:0004866]	sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase inhibitor activity [GO:0004866]
d3bx3a__d1h2tc1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mRNA binding [GO:0003729]; negative regulation of chromatin silencing involved in replicative cell aging [GO:0001308]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; protein localization [GO:0008104]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]; mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]; 7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	negative regulation of chromatin silencing involved in replicative cell aging [GO:0001308]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; protein localization [GO:0008104]	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene silencing by RNA [GO:0031047]; histone mRNA metabolic process [GO:0008334]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear export [GO:0051168]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell growth [GO:0030307]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of RNA binding [GO:1905216]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; regulation of mRNA processing [GO:0050684]; regulation of translational initiation [GO:0006446]; RNA catabolic process [GO:0006401]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]; snRNA transcription by RNA polymerase II [GO:0042795]; spliceosomal complex assembly [GO:0000245]; termination of RNA polymerase II transcription [GO:0006369]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; mRNA cap binding complex [GO:0005845]; nuclear cap binding complex [GO:0005846]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; RNA cap binding complex [GO:0034518]	mRNA binding [GO:0003729]	mRNA binding [GO:0003729]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA cap binding [GO:0000339]
d3bx4a__d1esla1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	caveola [GO:0005901]; clathrin-coated pit [GO:0005905]; cortical cytoskeleton [GO:0030863]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; oligosaccharide binding [GO:0070492]; phospholipase binding [GO:0043274]; sialic acid binding [GO:0033691]; transmembrane signaling receptor activity [GO:0004888]; actin filament-based process [GO:0030029]; activation of phospholipase C activity [GO:0007202]; calcium-mediated signaling [GO:0019722]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte migration involved in inflammatory response [GO:0002523]; leukocyte tethering or rolling [GO:0050901]; positive regulation of receptor internalization [GO:0002092]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]	regulation of cytokine activity [GO:0060300]	actin filament-based process [GO:0030029]; activation of phospholipase C activity [GO:0007202]; calcium-mediated signaling [GO:0019722]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte migration involved in inflammatory response [GO:0002523]; leukocyte tethering or rolling [GO:0050901]; positive regulation of receptor internalization [GO:0002092]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]	extracellular region [GO:0005576]	caveola [GO:0005901]; clathrin-coated pit [GO:0005905]; cortical cytoskeleton [GO:0030863]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; oligosaccharide binding [GO:0070492]; phospholipase binding [GO:0043274]; sialic acid binding [GO:0033691]; transmembrane signaling receptor activity [GO:0004888]
d3bx4d__d4gi0a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	regulation of cytokine activity [GO:0060300]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d3bx4d__d4kmb11__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	regulation of cytokine activity [GO:0060300]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d3bx7c__d1dbbl2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3bxfb__d5dw6a2__1			Firmicutes	Proteobacteria	carbohydrate binding [GO:0030246]; DNA binding [GO:0003677]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]		acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]			carbohydrate binding [GO:0030246]; DNA binding [GO:0003677]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d3bxga__d1fs5b___1			Firmicutes	Proteobacteria	carbohydrate binding [GO:0030246]; DNA binding [GO:0003677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbohydrate binding [GO:0030246]; DNA binding [GO:0003677]	glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]
d3bxua__d1ehja___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfur utilization [GO:0006791]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	sulfur utilization [GO:0006791]	anaerobic respiration [GO:0009061]			electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3bxva__d1q53a1__1		Viridiplantae	Crenarchaeota	Streptophyta	metal ion binding [GO:0046872]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; pollen tube adhesion [GO:0009865]		defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; pollen tube adhesion [GO:0009865]		cytosol [GO:0005829]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3bxxc__d1i36b2__1	Viridiplantae		Streptophyta	Euryarchaeota	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]; anthocyanin-containing compound biosynthetic process [GO:0009718]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	anthocyanin-containing compound biosynthetic process [GO:0009718]				coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3bxxe__d3mw9c1__1	Viridiplantae		Streptophyta		coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]; anthocyanin-containing compound biosynthetic process [GO:0009718]		anthocyanin-containing compound biosynthetic process [GO:0009718]				coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]	
d3bxxf__d1v3ub2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]; anthocyanin-containing compound biosynthetic process [GO:0009718]	cytoplasm [GO:0005737]; 13-prostaglandin reductase activity [GO:0036132]; 15-oxoprostaglandin 13-oxidase activity [GO:0047522]; 2-alkenal reductase [NAD(P)+] activity [GO:0032440]	anthocyanin-containing compound biosynthetic process [GO:0009718]			cytoplasm [GO:0005737]	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]	13-prostaglandin reductase activity [GO:0036132]; 15-oxoprostaglandin 13-oxidase activity [GO:0047522]; 2-alkenal reductase [NAD(P)+] activity [GO:0032440]
d3bxxf__d4b8za___1	Viridiplantae	Metazoa	Streptophyta	Chordata	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]; anthocyanin-containing compound biosynthetic process [GO:0009718]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	anthocyanin-containing compound biosynthetic process [GO:0009718]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]	coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]
d3by0a__d2q39b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	extracellular region [GO:0005576]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]
d3by0c__d5ljea___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; lipid homeostasis [GO:0055088]; retinoic acid biosynthetic process [GO:0002138]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	lipid homeostasis [GO:0055088]; retinoic acid biosynthetic process [GO:0002138]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]
d3by4b__d1v6ea1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule [GO:0005874]; cell differentiation [GO:0030154]; nervous system development [GO:0007399]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell differentiation [GO:0030154]; nervous system development [GO:0007399]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule [GO:0005874]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	
d3by4b__d4npna___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]
d3by8a__d5avfb1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; phosphorelay signal transduction system [GO:0000160]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction by protein phosphorylation [GO:0023014]	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; chemotaxis [GO:0006935]; signal transduction [GO:0007165]	phosphorelay signal transduction system [GO:0000160]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction by protein phosphorylation [GO:0023014]	chemotaxis [GO:0006935]; signal transduction [GO:0007165]	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]
d3byla__d4udga___1			Firmicutes		extracellular region [GO:0005576]; levansucrase activity [GO:0050053]; carbohydrate utilization [GO:0009758]		carbohydrate utilization [GO:0009758]		extracellular region [GO:0005576]		levansucrase activity [GO:0050053]	
d3byra__d3h90d2__1			Deinococcus-Thermus	Proteobacteria	integral component of membrane [GO:0016021]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadmium ion transmembrane transporter activity [GO:0015086]; cation transmembrane transporter activity [GO:0008324]; ferrous iron transmembrane transporter activity [GO:0015093]; identical protein binding [GO:0042802]; zinc efflux active transmembrane transporter activity [GO:0015341]; cadmium ion transport [GO:0015691]; cellular cadmium ion homeostasis [GO:0006876]; cellular iron ion homeostasis [GO:0006879]; cellular zinc ion homeostasis [GO:0006882]; iron ion transport [GO:0006826]; zinc ion transport [GO:0006829]		cadmium ion transport [GO:0015691]; cellular cadmium ion homeostasis [GO:0006876]; cellular iron ion homeostasis [GO:0006879]; cellular zinc ion homeostasis [GO:0006882]; iron ion transport [GO:0006826]; zinc ion transport [GO:0006829]	integral component of membrane [GO:0016021]	cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	cadmium ion transmembrane transporter activity [GO:0015086]; cation transmembrane transporter activity [GO:0008324]; ferrous iron transmembrane transporter activity [GO:0015093]; identical protein binding [GO:0042802]; zinc efflux active transmembrane transporter activity [GO:0015341]
d3byta__d1nd0d1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]
d3byta__d3gjel2__1			Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d3byyb2_d2rdhd2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d3byza__d4pzei1__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	fatty acid metabolic process [GO:0006631]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d3byzd__d4ro0l1__1	Metazoa		Chordata	Euryarchaeota	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	potassium ion transport [GO:0006813]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3bz1v__d3zowc___1				Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3bz4a2_d3vxqb2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3bz4c1_d4nqde2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3bz4g1_d1fdlh1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3bz4g2_d2ybrd___1	Metazoa	Metazoa	Chordata	Arthropoda	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	defense response [GO:0006952]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]
d3bzab1_d1f1xa2__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3bzac1_d4z6zd2__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3bzad2_d4jh3b___1			Actinobacteria	Firmicutes	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765]
d3bzda__d1boga1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d3bzdb2_d5i4da2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d3bzea2_d4pj5a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3bzec1_d2dd8h1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d3bzec1_d4gt7b1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3bzef2_d4pjie1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3bzeh2_d2ak4p1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3bzfc2_d3c60g2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d3bzfd__d5gs1k1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3bzka4_d2mo0a___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; mRNA binding [GO:0003729]; structural constituent of ribosome [GO:0003735]; nucleobase-containing compound metabolic process [GO:0006139]; translation [GO:0006412]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]	nucleobase-containing compound metabolic process [GO:0006139]; translation [GO:0006412]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	mRNA binding [GO:0003729]; structural constituent of ribosome [GO:0003735]	DNA binding [GO:0003677]
d3bzka5_d3ktqa1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; mRNA binding [GO:0003729]; structural constituent of ribosome [GO:0003735]; nucleobase-containing compound metabolic process [GO:0006139]; translation [GO:0006412]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	nucleobase-containing compound metabolic process [GO:0006139]; translation [GO:0006412]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	cytosol [GO:0005829]		mRNA binding [GO:0003729]; structural constituent of ribosome [GO:0003735]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]
d3bzpa1_d3bzsa___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]; protein secretion [GO:0009306]	protein secretion [GO:0009306]	protein secretion [GO:0009306]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]	dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]
d3bzta1_d5culb___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein secretion [GO:0009306]	protein secretion [GO:0009306]	protein secretion [GO:0009306]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]	
d3bzua__d1d4fd1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]
d3bzub2_d5gwra___1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	oxidoreductase activity [GO:0016491]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	oxidoreductase activity [GO:0016491]
d3bzx.1_d2vt1.1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; pathogenesis [GO:0009405]; protein secretion [GO:0009306]	protein secretion [GO:0009306]	pathogenesis [GO:0009405]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]	
d3bzy.1_d2jlha___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; pathogenesis [GO:0009405]; protein secretion [GO:0009306]	protein secretion [GO:0009306]	pathogenesis [GO:0009405]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]	
d3bzy.1_d3bzl.1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]; protein secretion [GO:0009306]	protein secretion [GO:0009306]	protein secretion [GO:0009306]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]	dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]
d3c09c1_d2j6eb1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3c09h1_d1hysd1__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3c0ea1_d4p8oa___1	Fungi		Ascomycota	Firmicutes	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d3c0ma1_d4j6mh___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d3c0nb1_d1bcph2__1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]			extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	identical protein binding [GO:0042802]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d3c0oa1_d2orjc1__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]		cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	identical protein binding [GO:0042802]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d3c0pa1_d1qj2i3__1	Viridiplantae		Streptophyta		extracellular space [GO:0005615]; cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]		cytokinin metabolic process [GO:0009690]		extracellular space [GO:0005615]		cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]	
d3c0va__d4bk7a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]	abscisic acid binding [GO:0010427]; cytokinin binding [GO:0044373]; gibberellin binding [GO:0010331]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d3c15a__d2w01f___1	Metazoa		Chordata	Cyanobacteria	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; phosphorus-oxygen lyase activity [GO:0016849]; cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556]	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; phosphorus-oxygen lyase activity [GO:0016849]
d3c16a__d2w01e___1	Metazoa		Chordata	Cyanobacteria	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; phosphorus-oxygen lyase activity [GO:0016849]; cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556]	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; phosphorus-oxygen lyase activity [GO:0016849]
d3c16c2_d2gtpb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; leukotriene signaling pathway [GO:0061737]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; cellular response to forskolin [GO:1904322]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; leukotriene signaling pathway [GO:0061737]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]	cell [GO:0005623]; cilium [GO:0005929]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]	adenylate cyclase activity [GO:0004016]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]	calmodulin binding [GO:0005516]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]
d3c1bc__d1p3bd___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3c1bg__d1p3ff___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3c1cg1_d3azle___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3c1ch1_d1zlab___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3c1ma1_d4jz7d___1			Euryarchaeota		cytosol [GO:0005829]; aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]; homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	cytosol [GO:0005829]; carbamate kinase activity [GO:0008804]; nucleotide binding [GO:0000166]; arginine deiminase pathway [GO:0019546]	homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	arginine deiminase pathway [GO:0019546]	cytosol [GO:0005829]	cytosol [GO:0005829]	aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]	carbamate kinase activity [GO:0008804]; nucleotide binding [GO:0000166]
d3c1nc1_d4f6ta___1			Euryarchaeota	Proteobacteria	cytosol [GO:0005829]; aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]; homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]; molybdenum ion binding [GO:0030151]; nutrient reservoir activity [GO:0045735]	homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]	molybdenum ion binding [GO:0030151]; nutrient reservoir activity [GO:0045735]
d3c1tc__d2oo5b1__1	Viridiplantae		Streptophyta	Proteobacteria	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]; anthocyanin-containing compound biosynthetic process [GO:0009718]	NAD binding [GO:0051287]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]; NADPH regeneration [GO:0006740]	anthocyanin-containing compound biosynthetic process [GO:0009718]	NADPH regeneration [GO:0006740]			coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]
d3c1vb__d1qx5r___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]
d3c1vb__d2lhla___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]
d3c1vc__d1qx5b___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]
d3c20a3_d2phma1__1		Metazoa	Euryarchaeota	Chordata	cytosol [GO:0005829]; aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]; homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	amino acid binding [GO:0016597]; cofactor binding [GO:0048037]; iron ion binding [GO:0005506]; phenylalanine 4-monooxygenase activity [GO:0004505]; protein homodimerization activity [GO:0042803]; L-phenylalanine catabolic process [GO:0006559]; L-phenylalanine metabolic process [GO:0006558]; protein hydroxylation [GO:0018126]; pteridine-containing compound metabolic process [GO:0042558]; tetrahydrobiopterin metabolic process [GO:0046146]; tyrosine biosynthetic process [GO:0006571]	homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	L-phenylalanine catabolic process [GO:0006559]; L-phenylalanine metabolic process [GO:0006558]; protein hydroxylation [GO:0018126]; pteridine-containing compound metabolic process [GO:0042558]; tetrahydrobiopterin metabolic process [GO:0046146]; tyrosine biosynthetic process [GO:0006571]	cytosol [GO:0005829]		aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]	amino acid binding [GO:0016597]; cofactor binding [GO:0048037]; iron ion binding [GO:0005506]; phenylalanine 4-monooxygenase activity [GO:0004505]; protein homodimerization activity [GO:0042803]
d3c20b3_d2j0wa3__1			Euryarchaeota	Proteobacteria	cytosol [GO:0005829]; aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]; homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	cytosol [GO:0005829]; aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]; homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]	homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	cytosol [GO:0005829]	aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]	aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]
d3c22b__d1g1ta1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	caveola [GO:0005901]; clathrin-coated pit [GO:0005905]; cortical cytoskeleton [GO:0030863]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; oligosaccharide binding [GO:0070492]; phospholipase binding [GO:0043274]; sialic acid binding [GO:0033691]; transmembrane signaling receptor activity [GO:0004888]; actin filament-based process [GO:0030029]; activation of phospholipase C activity [GO:0007202]; calcium-mediated signaling [GO:0019722]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte migration involved in inflammatory response [GO:0002523]; leukocyte tethering or rolling [GO:0050901]; positive regulation of receptor internalization [GO:0002092]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	actin filament-based process [GO:0030029]; activation of phospholipase C activity [GO:0007202]; calcium-mediated signaling [GO:0019722]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte migration involved in inflammatory response [GO:0002523]; leukocyte tethering or rolling [GO:0050901]; positive regulation of receptor internalization [GO:0002092]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	caveola [GO:0005901]; clathrin-coated pit [GO:0005905]; cortical cytoskeleton [GO:0030863]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	metal ion binding [GO:0046872]; oligosaccharide binding [GO:0070492]; phospholipase binding [GO:0043274]; sialic acid binding [GO:0033691]; transmembrane signaling receptor activity [GO:0004888]
d3c22c__d4gjxa___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d3c2ah1_d1jgvl2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3c2ah1_d1nfdf1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3c2ai1_d3fo9l1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3c2ai2_d4kucd2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	endoplasmic reticulum [GO:0005783]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3c2ca__d3o5cd1__1			Proteobacteria	Proteobacteria	electron transporter, transferring electrons within cytochrome c oxidase complex activity [GO:0045154]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthesis [GO:0015979]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	photosynthesis [GO:0015979]				electron transporter, transferring electrons within cytochrome c oxidase complex activity [GO:0045154]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3c2ka3_d1cf6a5__1	Metazoa		Chordata		cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]		damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	
d3c2la1_d4iqua1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3c2sa2_d1yedh1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3c2tb__d4ao5b1__1				Firmicutes	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3c2ua1_d1uypa2__1			Firmicutes	Thermotogae	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-fructofuranosidase activity [GO:0004564]
d3c2ub2_d2p3ia___1			Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; sialic acid binding [GO:0033691]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; receptor-mediated virion attachment to host cell [GO:0046813]; viral entry into host cell [GO:0046718]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; receptor-mediated virion attachment to host cell [GO:0046813]; viral entry into host cell [GO:0046718]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]		host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	sialic acid binding [GO:0033691]
d3c2ub2_d5kxea___1		Viridiplantae	Firmicutes	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]	carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]
d3c2wb1_d3s7na2__1			Proteobacteria	Deinococcus-Thermus	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3c2wd1_d3nhqf2__1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3c2wd3_d3f1ob___1		Metazoa	Proteobacteria	Chordata	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]		cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d3c2we1_d2klia1__1			Proteobacteria	Cyanobacteria	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay sensor kinase activity [GO:0000155]; detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	phosphorelay sensor kinase activity [GO:0000155]
d3c2we1_d3ksfh___1			Proteobacteria		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]				ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	
d3c2xa__d2rkqa1__1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; peptidoglycan receptor activity [GO:0016019]; zinc ion binding [GO:0008270]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of peptidoglycan [GO:0032499]; innate immune response [GO:0045087]; negative regulation of natural killer cell differentiation involved in immune response [GO:0032827]; positive regulation of peptidoglycan recognition protein signaling pathway [GO:0061059]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of peptidoglycan [GO:0032499]; innate immune response [GO:0045087]; negative regulation of natural killer cell differentiation involved in immune response [GO:0032827]; positive regulation of peptidoglycan recognition protein signaling pathway [GO:0061059]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; peptidoglycan receptor activity [GO:0016019]; zinc ion binding [GO:0008270]
d3c32a__d1p1qb___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3c33a__d3b7df___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3c34a__d3r26a___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; ATPase-coupled molybdate transmembrane transporter activity [GO:0015412]; molybdate ion binding [GO:0030973]; molybdenum ion binding [GO:0030151]; tungstate binding [GO:1901359]; molybdate ion transport [GO:0015689]; response to chromate [GO:0046687]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	molybdate ion transport [GO:0015689]; response to chromate [GO:0046687]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	ATPase-coupled molybdate transmembrane transporter activity [GO:0015412]; molybdate ion binding [GO:0030973]; molybdenum ion binding [GO:0030151]; tungstate binding [GO:1901359]
d3c35b__d4yb6d1__1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	histidine biosynthetic process [GO:0000105]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d3c36b__d3rn8a___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3c36b__d5m8hg___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	cytoplasm [GO:0005737]; histidine biosynthetic process [GO:0000105]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	histidine biosynthetic process [GO:0000105]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	
d3c3ia__d1pkja___1				Euryarchaeota	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d3c3ib__d1xs6e___1				Proteobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]		cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d3c3nc__d2tmdb1__1				Proteobacteria	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]
d3c3sa1_d1szxa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3c3sa1_d2cdyd1__1	Metazoa		Chordata	Deinococcus-Thermus	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3c3sb2_d2bpib2__1	Metazoa		Chordata	Apicomplexa	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3c3ta2_d2cdyc2__1	Metazoa		Chordata	Deinococcus-Thermus	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3c3ta2_d4l2dc2__1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3c3tb1_d3ak3c1__1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3c3tb2_d4guni2__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3c45a2_d1einb___1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	triglyceride lipase activity [GO:0004806]
d3c49a2_d5h04a2__1	Metazoa		Chordata	Firmicutes	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; catalytic activity [GO:0003824]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]; pathogenesis [GO:0009405]	DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	pathogenesis [GO:0009405]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]	extracellular region [GO:0005576]	catalytic activity [GO:0003824]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]	nucleotide binding [GO:0000166]
d3c4ea__d3soca1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; manganese ion binding [GO:0030145]; protein serine/threonine kinase activity [GO:0004674]; ribosomal small subunit binding [GO:0043024]; transcription factor binding [GO:0008134]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular detoxification [GO:1990748]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan metabolic process [GO:0030212]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561]	activin receptor complex [GO:0048179]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; inhibin-betaglycan-ActRII complex [GO:0034673]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; activin binding [GO:0048185]; activin-activated receptor activity [GO:0017002]; ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; coreceptor activity [GO:0015026]; growth factor binding [GO:0019838]; inhibin binding [GO:0034711]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]; activin receptor signaling pathway [GO:0032924]; anterior/posterior pattern specification [GO:0009952]; BMP signaling pathway [GO:0030509]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; determination of left/right symmetry [GO:0007368]; embryonic skeletal system development [GO:0048706]; gastrulation with mouth forming second [GO:0001702]; mesoderm development [GO:0007498]; penile erection [GO:0043084]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of nitric-oxide synthase activity [GO:0050999]; Sertoli cell proliferation [GO:0060011]; sperm ejaculation [GO:0042713]; spermatogenesis [GO:0007283]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular detoxification [GO:1990748]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan metabolic process [GO:0030212]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561]	activin receptor signaling pathway [GO:0032924]; anterior/posterior pattern specification [GO:0009952]; BMP signaling pathway [GO:0030509]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; determination of left/right symmetry [GO:0007368]; embryonic skeletal system development [GO:0048706]; gastrulation with mouth forming second [GO:0001702]; mesoderm development [GO:0007498]; penile erection [GO:0043084]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of nitric-oxide synthase activity [GO:0050999]; Sertoli cell proliferation [GO:0060011]; spermatogenesis [GO:0007283]; sperm ejaculation [GO:0042713]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	activin receptor complex [GO:0048179]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; inhibin-betaglycan-ActRII complex [GO:0034673]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	ATP binding [GO:0005524]; manganese ion binding [GO:0030145]; protein serine/threonine kinase activity [GO:0004674]; ribosomal small subunit binding [GO:0043024]; transcription factor binding [GO:0008134]	activin-activated receptor activity [GO:0017002]; activin binding [GO:0048185]; ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; coreceptor activity [GO:0015026]; growth factor binding [GO:0019838]; inhibin binding [GO:0034711]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]
d3c4ha1_d1uk1a1__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; catalytic activity [GO:0003824]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	catalytic activity [GO:0003824]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3c4ha1_d1wokb1__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; catalytic activity [GO:0003824]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	catalytic activity [GO:0003824]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3c4ib__d4qjnc___1				Firmicutes		DNA binding [GO:0003677]; chromosome condensation [GO:0030261]		chromosome condensation [GO:0030261]				DNA binding [GO:0003677]
d3c4pb__d1xxmd___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]	beta-lactamase activity [GO:0008800]; beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]		beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]	extracellular region [GO:0005576]			beta-lactamase activity [GO:0008800]
d3c5fb1_d4nxza1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d3c5zb1_d1m7db1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3c5zb2_d4v1dd___1	Metazoa	Metazoa	Chordata	Arthropoda	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	defense response [GO:0006952]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]
d3c5zc2_d5u16a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3c5zd1_d3lrsl1__1	Metazoa		Chordata		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	
d3c5ze1_d5wjob1__1	Metazoa		Chordata		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	
d3c5ze2_d3zhka1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3c5zf1_d2nw2b2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3c5zh1_d4pjhf2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3c60a2_d3s37l2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell junction [GO:0030054]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; sorting endosome [GO:0097443]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; growth factor binding [GO:0019838]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; angiogenesis [GO:0001525]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic hemopoiesis [GO:0035162]; endothelial cell differentiation [GO:0045446]; endothelium development [GO:0003158]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of gene expression [GO:0010629]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vasculogenesis [GO:2001214]; protein autophosphorylation [GO:0046777]; protein kinase B signaling [GO:0043491]; regulation of cell shape [GO:0008360]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	angiogenesis [GO:0001525]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic hemopoiesis [GO:0035162]; endothelial cell differentiation [GO:0045446]; endothelium development [GO:0003158]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of gene expression [GO:0010629]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vasculogenesis [GO:2001214]; protein autophosphorylation [GO:0046777]; protein kinase B signaling [GO:0043491]; regulation of cell shape [GO:0008360]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral process [GO:0016032]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; sorting endosome [GO:0097443]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; growth factor binding [GO:0019838]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d3c60b2_d3bz4a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3c60b2_d5ebgb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; T cell mediated immunity [GO:0002456]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell surface receptor signaling pathway [GO:0007166]; cytotoxic T cell differentiation [GO:0045065]; T cell mediated immunity [GO:0002456]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	
d3c60c1_d4dk6a1__1	Metazoa		Chordata		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	mitochondrion [GO:0005739]; alpha-catenin binding [GO:0045294]; nucleic acid binding [GO:0003676]; mitochondrial RNA modification [GO:1900864]; RNA nucleotide deletion [GO:0070706]; RNA nucleotide insertion [GO:0070705]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	mitochondrial RNA modification [GO:1900864]; RNA nucleotide deletion [GO:0070706]; RNA nucleotide insertion [GO:0070705]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	mitochondrion [GO:0005739]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	alpha-catenin binding [GO:0045294]; nucleic acid binding [GO:0003676]
d3c60c2_d2axga2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3c60e1_d4k07j___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d3c60e1_d4xmpl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3c60e2_d3cfke1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3c60g1_d5b6fg2__1	Metazoa		Chordata		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]		cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	
d3c60h1_d5niud1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	
d3c62b__d2yl1a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3c62b__d3c63b___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3c62d__d2xlva___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3c62d__d3fooj___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3c63c__d2yl7a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3c66b1_d2q66a1__1	Fungi	Fungi	Ascomycota	Ascomycota	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]; mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]; snoRNA polyadenylation [GO:0071050]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]	mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; polynucleotide adenylyltransferase activity [GO:0004652]; RNA binding [GO:0003723]
d3c6ga1_d4bf4a___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; vitamin D3 25-hydroxylase activity [GO:0030343]; calcitriol biosynthetic process from calciol [GO:0036378]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; response to cesium ion [GO:0010164]; response to ionizing radiation [GO:0010212]; vitamin D metabolic process [GO:0042359]; vitamin metabolic process [GO:0006766]; xenobiotic metabolic process [GO:0006805]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	calcitriol biosynthetic process from calciol [GO:0036378]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; response to cesium ion [GO:0010164]; response to ionizing radiation [GO:0010212]; vitamin D metabolic process [GO:0042359]; vitamin metabolic process [GO:0006766]; xenobiotic metabolic process [GO:0006805]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; vitamin D3 25-hydroxylase activity [GO:0030343]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3c6la1_d4kjwd1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3c6le1_d1vfbb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3c6le2_d4f7eb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3c6lg1_d5f7hb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3c6lg2_d5wkea1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3c6qa__d1gudb___1			Thermotogae	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; monosaccharide binding [GO:0048029]; carbohydrate transport [GO:0008643]		carbohydrate transport [GO:0008643]	outer membrane-bounded periplasmic space [GO:0030288]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]		monosaccharide binding [GO:0048029]
d3c6qc__d3uuga___1			Thermotogae	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]; chemotaxis [GO:0006935]		chemotaxis [GO:0006935]	outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]		
d3c6qd__d2puda2__1			Thermotogae	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]; negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]		negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]	outer membrane-bounded periplasmic space [GO:0030288]	cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]
d3c6sa1_d5m2ik___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d3c6sc1_d4z7ue1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	nutrient reservoir activity [GO:0045735]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	nutrient reservoir activity [GO:0045735]
d3c6sg2_d2guoa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3c6ta3_d2g8ua___1				Firmicutes	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d3c6ya__d2dr0b1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d3c6ya__d3x3he___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]					aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]
d3c70a__d4pnza2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3c73a__d16gsa2__1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3c74d__d1rxci___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	uridine phosphorylase activity [GO:0004850]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]
d3c75a__d2gi0b___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]; methylamine metabolic process [GO:0030416]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	methylamine metabolic process [GO:0030416]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3c77x__d4tkba___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	vasodilation [GO:0042311]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]
d3c7la__d2gtpc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; membrane raft [GO:0045121]; GTPase activator activity [GO:0005096]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; leukotriene signaling pathway [GO:0061737]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; leukotriene signaling pathway [GO:0061737]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; membrane raft [GO:0045121]	cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]	GTPase activator activity [GO:0005096]	calmodulin binding [GO:0005516]; G-protein alpha-subunit binding [GO:0001965]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]
d3c7lb__d2jnua1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; membrane raft [GO:0045121]; GTPase activator activity [GO:0005096]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]	cell junction [GO:0030054]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; microtubule [GO:0005874]; nuclear body [GO:0016604]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; spindle [GO:0005819]; spindle pole [GO:0000922]; G-protein alpha-subunit binding [GO:0001965]; GDP-dissociation inhibitor activity [GO:0005092]; GTPase activating protein binding [GO:0032794]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; microtubule binding [GO:0008017]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; mitotic cell cycle [GO:0000278]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of synaptic plasticity [GO:0031914]; nucleocytoplasmic transport [GO:0006913]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of neurogenesis [GO:0050769]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to oxidative stress [GO:0006979]; spindle organization [GO:0007051]; visual learning [GO:0008542]; zygote asymmetric cell division [GO:0010070]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]	cell division [GO:0051301]; chromosome segregation [GO:0007059]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; mitotic cell cycle [GO:0000278]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of synaptic plasticity [GO:0031914]; nucleocytoplasmic transport [GO:0006913]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of neurogenesis [GO:0050769]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; response to oxidative stress [GO:0006979]; spindle organization [GO:0007051]; visual learning [GO:0008542]; zygote asymmetric cell division [GO:0010070]	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; membrane raft [GO:0045121]	cell junction [GO:0030054]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; microtubule [GO:0005874]; nuclear body [GO:0016604]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; spindle [GO:0005819]; spindle pole [GO:0000922]	GTPase activator activity [GO:0005096]	GDP-dissociation inhibitor activity [GO:0005092]; G-protein alpha-subunit binding [GO:0001965]; GTPase activating protein binding [GO:0032794]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; microtubule binding [GO:0008017]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]
d3c7mb__d3tkqd___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; periplasmic space [GO:0042597]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	protein disulfide oxidoreductase activity [GO:0015035]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d3c7nb3_d3r6mc1__1	Metazoa		Chordata	Proteobacteria	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	
d3c7ud__d3gmxb___1			Proteobacteria	Actinobacteria	beta-lactamase activity [GO:0008800]; beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]		beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]				beta-lactamase activity [GO:0008800]	
d3c7vb__d3gmvx___1			Proteobacteria	Actinobacteria	beta-lactamase activity [GO:0008800]; beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]		beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]				beta-lactamase activity [GO:0008800]	
d3c7vd__d3gmwd___1			Proteobacteria	Actinobacteria	beta-lactamase activity [GO:0008800]; beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]		beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]				beta-lactamase activity [GO:0008800]	
d3c7wa__d1c6da___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3c7wa__d3ajna___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3c7ya__d3wvxa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3c80a__d1b5ua___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3c83a__d1bb5b___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3c83a__d3sb9b1__1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3c84a1_d5afhb___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3c88a__d4g0dd1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	negative regulation of neurotransmitter secretion [GO:0046929]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d3c8ba__d1g49a___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	negative regulation of neurotransmitter secretion [GO:0046929]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3c8ja__d4pp8a___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; MHC class Ib receptor activity [GO:0032394]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]; adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of apoptotic process [GO:0043065]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	cell adhesion [GO:0007155]	adaptive immune response [GO:0002250]; cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; defense response to Gram-positive bacterium [GO:0050830]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of GTPase activity [GO:0034260]; negative regulation of natural killer cell chemotaxis [GO:2000502]; positive regulation of apoptotic process [GO:0043065]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; kinase binding [GO:0019900]; MHC class Ib receptor activity [GO:0032394]; MHC class I protein binding [GO:0042288]; protein homodimerization activity [GO:0042803]; signaling receptor activity [GO:0038023]
d3c8jc__d1kzc1___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	cell adhesion [GO:0007155]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]
d3c8ka1_d1uqsa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3c8kb__d3ux9b2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]
d3c8kd__d3ff7d___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3c8ra__d1mell___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3c8sa__d251la___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3c8ya2_d3w5uf___1		Viridiplantae	Firmicutes	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]		electron transport chain [GO:0022900]; photosynthesis [GO:0015979]		chloroplast thylakoid membrane protein complex [GO:0098807]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d3c8ya2_d4c7za1__1			Firmicutes	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3c90b__d2yaza___1			Actinobacteria		cell wall [GO:0005618]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosyl-ATP diphosphatase activity [GO:0004636]; histidine biosynthetic process [GO:0000105]; response to host iron concentration [GO:0075139]	nucleoplasm [GO:0005654]; dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]	histidine biosynthetic process [GO:0000105]; response to host iron concentration [GO:0075139]		cell wall [GO:0005618]; cytoplasm [GO:0005737]	nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosyl-ATP diphosphatase activity [GO:0004636]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]
d3c91c1_d1yarc___1			Euryarchaeota		cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	proteasome activator complex [GO:0008537]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	
d3c91h1_d5l5tc___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3c91k1_d5lf7t___1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	proteasomal protein catabolic process [GO:0010498]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3c91m1_d3gpjr___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3c91n1_d5lexa___1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	proteasomal protein catabolic process [GO:0010498]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3c91r1_d1apz.1__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity [GO:0003948]; peptidase activity [GO:0008233]; protein self-association [GO:0043621]; neutrophil degranulation [GO:0043312]; protein deglycosylation [GO:0006517]	proteasomal protein catabolic process [GO:0010498]	neutrophil degranulation [GO:0043312]; protein deglycosylation [GO:0006517]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity [GO:0003948]; peptidase activity [GO:0008233]; protein self-association [GO:0043621]
d3c91t1_d5l67i___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3c91x1_d4hnzl1__1			Euryarchaeota		cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; HslUV protease complex [GO:0009376]; kinetoplast [GO:0020023]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nuclear lumen [GO:0031981]; proteasome core complex [GO:0005839]; ATP-dependent peptidase activity [GO:0004176]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; mitochondrial DNA inheritance [GO:0033955]; mitochondrial DNA replication [GO:0006264]; proteolysis involved in cellular protein catabolic process [GO:0051603]; rolling circle DNA replication [GO:0070581]	proteasomal protein catabolic process [GO:0010498]	mitochondrial DNA inheritance [GO:0033955]; mitochondrial DNA replication [GO:0006264]; proteolysis involved in cellular protein catabolic process [GO:0051603]; rolling circle DNA replication [GO:0070581]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; HslUV protease complex [GO:0009376]; kinetoplast [GO:0020023]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nuclear lumen [GO:0031981]; proteasome core complex [GO:0005839]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	ATP-dependent peptidase activity [GO:0004176]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3c92a1_d4jsqa___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3c92d1_d2zcy1___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3c92f1_d4q1sr___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3c92f1_d5l66q___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3c92s1_d4qvyf___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3c92w1_d5l5yz___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3c96a2_d1cj4a2__1			Proteobacteria	Proteobacteria	FAD binding [GO:0071949]; monooxygenase activity [GO:0004497]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]		benzoate catabolic process via hydroxylation [GO:0043640]			FAD binding [GO:0071949]; monooxygenase activity [GO:0004497]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d3c96a2_d2igob2__1		Fungi	Proteobacteria	Basidiomycota	FAD binding [GO:0071949]; monooxygenase activity [GO:0004497]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]					FAD binding [GO:0071949]; monooxygenase activity [GO:0004497]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]
d3c9ea__d1f29c___1	Metazoa		Chordata		endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cysteine-type endopeptidase activity [GO:0004197]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]		endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]	cysteine-type endopeptidase activity [GO:0004197]
d3c9fa2_d5xcha___1	Fungi		Ascomycota		cytosol [GO:0005829]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; nucleotide catabolic process [GO:0009166]	cytosol [GO:0005829]; endosome [GO:0005768]; retromer complex [GO:0030904]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]	nucleotide catabolic process [GO:0009166]	intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]	cytosol [GO:0005829]	cytosol [GO:0005829]; endosome [GO:0005768]; retromer complex [GO:0030904]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	
d3c9na1_d1fvdd1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3c9na2_d3wexa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3c9sb1_d5dd7b1__1			Aquificae	Proteobacteria	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]			ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]
d3c9ta2_d1clid2__1			Aquificae	Proteobacteria	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytosol [GO:0005829]; ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]		cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]	ATP binding [GO:0005524]; phosphoribosylamine-glycine ligase activity [GO:0004637]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]
d3c9tb2_d2hs4a3__1			Aquificae	Thermotogae	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]
d3c9tb2_d5vk4a2__1			Aquificae	Proteobacteria	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	'de novo' IMP biosynthetic process [GO:0006189]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]	ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]
d3c9ub2_d2zaub2__1			Aquificae	Aquificae	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]; selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	selenium compound metabolic process [GO:0001887]; selenocysteine biosynthetic process [GO:0016260]; tRNA seleno-modification [GO:0070329]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; selenide, water dikinase activity [GO:0004756]
d3c9za1_d4za3b2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3c9za2_d1rzod1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]		endoplasmic reticulum [GO:0005783]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3ca3a1_d2e4ma2__1	Viridiplantae		Streptophyta		carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	
d3ca5a2_d1qxmb2__1	Viridiplantae		Streptophyta		carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]
d3ca6a2_d2r9kb1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3ca6a2_d4lo0a2__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]				carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	
d3ca9a1_d3zf6a___1					dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3ca9b1_d3hzaa1__1				Actinobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3cadb__d4m17k___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cell adhesion [GO:0007155]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d3caeb__d2pfja___1					deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]			deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]
d3caej__d1m0ib___1					deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]	degradation of host chromosome by virus [GO:0099015]; DNA integration [GO:0015074]; suppression by virus of host gene expression [GO:0039657]			deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]
d3caga__d1b4ad2__1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3cagb__d2p5ma___1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; arginine catabolic process to ornithine [GO:0019547]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3cagd__d1xxbd___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]
d3cagf__d1xxaf___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	cytoplasm [GO:0005737]; arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	arginine biosynthetic process [GO:0006526]; protein complex oligomerization [GO:0051259]	arginine biosynthetic process [GO:0006526]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; plasmid recombination [GO:0042150]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; protein hexamerization [GO:0034214]; regulation of arginine biosynthetic process [GO:1900079]; regulation of arginine catabolic process [GO:1900081]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	arginine binding [GO:0034618]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	arginine binding [GO:0034618]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]
d3caha1_d3rtib1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		endoplasmic reticulum [GO:0005783]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3caha2_d1hwnb1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; metabolic process [GO:0008152]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; metabolic process [GO:0008152]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3caja__d4bcwa___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3cb0c__d2x1ka1__1			Proteobacteria	Deinococcus-Thermus	4-hydroxyphenylacetate 3-monooxygenase activity [GO:0052881]; FMN binding [GO:0010181]	cofactor binding [GO:0048037]					4-hydroxyphenylacetate 3-monooxygenase activity [GO:0052881]; FMN binding [GO:0010181]	cofactor binding [GO:0048037]
d3cb0d__d1wlkc___1			Proteobacteria	Proteobacteria	4-hydroxyphenylacetate 3-monooxygenase activity [GO:0052881]; FMN binding [GO:0010181]	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	4-hydroxyphenylacetate 3-monooxygenase activity [GO:0052881]; FMN binding [GO:0010181]	cofactor binding [GO:0048037]
d3cb7a1_d4b0da___1	Metazoa	Metazoa	Arthropoda	Chordata	lysozyme activity [GO:0003796]; metabolic process [GO:0008152]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	metabolic process [GO:0008152]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3cb7b1_d2dbtc___1	Metazoa		Arthropoda	Actinobacteria	lysozyme activity [GO:0003796]; metabolic process [GO:0008152]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]		extracellular region [GO:0005576]	lysozyme activity [GO:0003796]	carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]
d3cbsa__d3fekb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3cc0a1_d3stje2__1	Metazoa		Chordata	Proteobacteria	aggresome [GO:0016235]; apical part of cell [GO:0045177]; clathrin-coated endocytic vesicle [GO:0045334]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein binding, bridging [GO:0030674]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; Rac GTPase binding [GO:0048365]; beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cellular protein localization [GO:0034613]; cochlea morphogenesis [GO:0090103]; convergent extension involved in neural plate elongation [GO:0022007]; heart development [GO:0007507]; hippo signaling [GO:0035329]; membrane organization [GO:0061024]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neural tube closure [GO:0001843]; non-canonical Wnt signaling pathway [GO:0035567]; outflow tract morphogenesis [GO:0003151]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of transcription, DNA-templated [GO:0045893]; segment specification [GO:0007379]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cellular protein localization [GO:0034613]; cochlea morphogenesis [GO:0090103]; convergent extension involved in neural plate elongation [GO:0022007]; heart development [GO:0007507]; hippo signaling [GO:0035329]; membrane organization [GO:0061024]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neural tube closure [GO:0001843]; non-canonical Wnt signaling pathway [GO:0035567]; outflow tract morphogenesis [GO:0003151]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of transcription, DNA-templated [GO:0045893]; segment specification [GO:0007379]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	aggresome [GO:0016235]; apical part of cell [GO:0045177]; clathrin-coated endocytic vesicle [GO:0045334]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; lateral plasma membrane [GO:0016328]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]	frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein binding, bridging [GO:0030674]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; Rac GTPase binding [GO:0048365]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]
d3cc2f1_d1w3ex1__1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	cytosolic large ribosomal subunit [GO:0022625]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]
d3cc2f1_d2vgma3__1		Fungi	Euryarchaeota	Ascomycota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; Dom34-Hbs1 complex [GO:1990533]; endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; ribosome binding [GO:0043022]; cell division [GO:0051301]; meiotic cell cycle [GO:0051321]; nonfunctional rRNA decay [GO:0070651]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; positive regulation of translation [GO:0045727]; ribosome disassembly [GO:0032790]; RNA surveillance [GO:0071025]; translation [GO:0006412]	translation [GO:0006412]	cell division [GO:0051301]; meiotic cell cycle [GO:0051321]; nonfunctional rRNA decay [GO:0070651]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; positive regulation of translation [GO:0045727]; ribosome disassembly [GO:0032790]; RNA surveillance [GO:0071025]; translation [GO:0006412]	ribosome [GO:0005840]	cytoplasm [GO:0005737]; Dom34-Hbs1 complex [GO:1990533]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; ribosome binding [GO:0043022]
d3cc2s1_d2vhnt1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d3cc5b__d1xf3a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cc7b1_d4m0lc2__1			Euryarchaeota	Crenarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	translation [GO:0006412]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	ribosome [GO:0005840]	cytosol [GO:0005829]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d3ccbc2_d1u8eb2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3ccca2_d4x6xb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3cccb2_d3ia2c___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]
d3cccd2_d1ffca___1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	cutinase activity [GO:0050525]
d3ccep1_d1n8rq___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d3cchb__d4gw5a1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3cchh__d4xt1c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell [GO:0005623]; cell projection [GO:0042995]; cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; CCR chemokine receptor binding [GO:0048020]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; CX3C chemokine receptor binding [GO:0031737]; CXCR1 chemokine receptor binding [GO:0045237]; integrin binding [GO:0005178]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; autocrine signaling [GO:0035425]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; integrin activation [GO:0033622]; leukocyte adhesive activation [GO:0050902]; leukocyte chemotaxis [GO:0030595]; leukocyte migration involved in inflammatory response [GO:0002523]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; microglial cell activation [GO:0001774]; microglial cell proliferation [GO:0061518]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of glutamate receptor signaling pathway [GO:1900450]; negative regulation of hippocampal neuron apoptotic process [GO:0110091]; negative regulation of interleukin-1 alpha production [GO:0032690]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron migration [GO:2001223]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; neuron cellular homeostasis [GO:0070050]; neuron remodeling [GO:0016322]; neutrophil chemotaxis [GO:0030593]; positive chemotaxis [GO:0050918]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcium-independent cell-cell adhesion [GO:0051041]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta1 production [GO:0032914]; regulation of lipopolysaccharide-mediated signaling pathway [GO:0031664]; regulation of neurogenesis [GO:0050767]; regulation of synaptic plasticity [GO:0048167]; response to ischemia [GO:0002931]; synapse pruning [GO:0098883]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; autocrine signaling [GO:0035425]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; cell chemotaxis [GO:0060326]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; integrin activation [GO:0033622]; leukocyte adhesive activation [GO:0050902]; leukocyte chemotaxis [GO:0030595]; leukocyte migration involved in inflammatory response [GO:0002523]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; microglial cell activation [GO:0001774]; microglial cell proliferation [GO:0061518]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of glutamate receptor signaling pathway [GO:1900450]; negative regulation of hippocampal neuron apoptotic process [GO:0110091]; negative regulation of interleukin-1 alpha production [GO:0032690]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron migration [GO:2001223]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; neuron cellular homeostasis [GO:0070050]; neuron remodeling [GO:0016322]; neutrophil chemotaxis [GO:0030593]; positive chemotaxis [GO:0050918]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcium-independent cell-cell adhesion [GO:0051041]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta1 production [GO:0032914]; regulation of lipopolysaccharide-mediated signaling pathway [GO:0031664]; regulation of neurogenesis [GO:0050767]; regulation of synaptic plasticity [GO:0048167]; response to ischemia [GO:0002931]; synapse pruning [GO:0098883]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell [GO:0005623]; cell projection [GO:0042995]; cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	CCR chemokine receptor binding [GO:0048020]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; CX3C chemokine receptor binding [GO:0031737]; CXCR1 chemokine receptor binding [GO:0045237]; integrin binding [GO:0005178]; signaling receptor binding [GO:0005102]
d3cchk__d3lrgb1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ccjb1_d4c0sb2__1		Metazoa	Euryarchaeota	Chordata	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	nucleus [GO:0005634]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	translation [GO:0006412]		ribosome [GO:0005840]	nucleus [GO:0005634]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3cckb__d2mtia___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cellular response to drug [GO:0035690]	integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]	cellular response to drug [GO:0035690]		external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]	integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]	carbohydrate binding [GO:0030246]
d3ccmb1_d1vs8d1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d3ccmf1_d1x52a1__1		Metazoa	Euryarchaeota	Chordata	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; ribosome binding [GO:0043022]; cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome organization [GO:0051276]; endoderm development [GO:0007492]; inner cell mass cell proliferation [GO:0001833]; mesenchymal to epithelial transition [GO:0060231]; nonfunctional rRNA decay [GO:0070651]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; positive regulation of BMP signaling pathway [GO:0030513]; ribosome disassembly [GO:0032790]; RNA surveillance [GO:0071025]; stem cell population maintenance [GO:0019827]	translation [GO:0006412]	cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome organization [GO:0051276]; endoderm development [GO:0007492]; inner cell mass cell proliferation [GO:0001833]; mesenchymal to epithelial transition [GO:0060231]; nonfunctional rRNA decay [GO:0070651]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; positive regulation of BMP signaling pathway [GO:0030513]; ribosome disassembly [GO:0032790]; RNA surveillance [GO:0071025]; stem cell population maintenance [GO:0019827]	ribosome [GO:0005840]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; ribosome binding [GO:0043022]
d3ccpa__d5sw4a2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3ccqb1_d1aipb1__1			Euryarchaeota	Deinococcus-Thermus	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	translation [GO:0006412]		ribosome [GO:0005840]	cytoplasm [GO:0005737]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3ccqf1_d1rlgb___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]; ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; ribosome biogenesis [GO:0042254]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	translation [GO:0006412]	ribosome biogenesis [GO:0042254]; translation [GO:0006412]; tRNA 5'-leader removal [GO:0001682]	ribosome [GO:0005840]	cytoplasm [GO:0005737]; ribonucleoprotein complex [GO:1990904]; ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	ribonuclease P activity [GO:0004526]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d3ccsf1_d1e7ka___1		Metazoa	Euryarchaeota	Chordata	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	box C/D snoRNP complex [GO:0031428]; dense fibrillar component [GO:0001651]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; small-subunit processome [GO:0032040]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4atac snRNP [GO:0005690]; ATPase binding [GO:0051117]; box C/D snoRNA binding [GO:0034512]; RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511]; U4 snRNA binding [GO:0030621]; U4atac snRNA binding [GO:0030622]; box C/D snoRNP assembly [GO:0000492]; maturation of LSU-rRNA [GO:0000470]; mRNA splicing, via spliceosome [GO:0000398]; rRNA processing [GO:0006364]; single fertilization [GO:0007338]	translation [GO:0006412]	box C/D snoRNP assembly [GO:0000492]; maturation of LSU-rRNA [GO:0000470]; mRNA splicing, via spliceosome [GO:0000398]; rRNA processing [GO:0006364]; single fertilization [GO:0007338]	ribosome [GO:0005840]	box C/D snoRNP complex [GO:0031428]; dense fibrillar component [GO:0001651]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; small-subunit processome [GO:0032040]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4atac snRNP [GO:0005690]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	ATPase binding [GO:0051117]; box C/D snoRNA binding [GO:0034512]; RNA binding [GO:0003723]; U3 snoRNA binding [GO:0034511]; U4atac snRNA binding [GO:0030622]; U4 snRNA binding [GO:0030621]
d3ccsp1_d1jj2o___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d3ccub1_d3cw2e2__1			Euryarchaeota	Crenarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	translation [GO:0006412]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	ribosome [GO:0005840]	cytosol [GO:0005829]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d3ccxa__d1gwua___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]; vacuole [GO:0005773]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3cd4a2_d5durl1__1	Metazoa		Chordata	Negarnaviricota	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	host cell surface receptor binding [GO:0046789]
d3cd6b1_d4m0le2__1			Euryarchaeota	Crenarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	translation [GO:0006412]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	ribosome [GO:0005840]	cytosol [GO:0005829]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d3cd6f1_d1kqsf___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d3cd6i1_d2z4li1__1			Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	
d3cd6p1_d1k8aq___1			Euryarchaeota	Euryarchaeota	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	ribosome [GO:0005840]	ribosome [GO:0005840]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d3cdca__d3eotl2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cdfa__d4hd9a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; integrin binding involved in cell-matrix adhesion [GO:0098640]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]	integrin binding involved in cell-matrix adhesion [GO:0098640]
d3cdfa__d4xbgd1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; identical protein binding [GO:0042802]	
d3cdfc__d5vr9l1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; identical protein binding [GO:0042802]	
d3cdfd__d1dqdl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; identical protein binding [GO:0042802]	
d3cdfe__d2cdea1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cdfe__d4edxa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]	cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]
d3cdgc1_d4u0rc2__1	Metazoa		Chordata	Apicomplexa	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3cdgc1_d5jo5l2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3cdge1_d2go0a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; oligosaccharide binding [GO:0070492]; peptidoglycan binding [GO:0042834]; transmembrane signaling receptor activity [GO:0004888]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; cell wall disruption in other organism [GO:0044278]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of keratinocyte differentiation [GO:0045617]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of wound healing [GO:0090303]; response to peptide hormone [GO:0043434]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; cell wall disruption in other organism [GO:0044278]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of keratinocyte differentiation [GO:0045617]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of wound healing [GO:0090303]; response to peptide hormone [GO:0043434]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; oligosaccharide binding [GO:0070492]; peptidoglycan binding [GO:0042834]; transmembrane signaling receptor activity [GO:0004888]
d3cdgj1_d4c9fd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; (1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	(1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]
d3cdgj1_d4j6jd___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d3cdoa__d1ua6y___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3cdoc__d1gb5a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3cdya__d2q8al1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cdya__d4y5xg___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]	erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]
d3ce4a__d2aala1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	
d3ceea__d5tviw___1		Viridiplantae		Streptophyta		lipid binding [GO:0008289]; lipid transport [GO:0006869]		lipid transport [GO:0006869]				lipid binding [GO:0008289]
d3cefb1_d3ef2b1__1		Fungi		Basidiomycota		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d3cefb2_d4qd2c1__1		Metazoa		Chordata		actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]		adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]		actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]		alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d3ceia1_d1kkcx1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to iron ion [GO:0071281]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to iron ion [GO:0071281]		cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ceia2_d1szxb2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to iron ion [GO:0071281]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cellular response to iron ion [GO:0071281]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	cytosol [GO:0005829]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ceia2_d4gunk2__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to iron ion [GO:0071281]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to iron ion [GO:0071281]		cytosol [GO:0005829]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ceib1_d1wb7a1__1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to iron ion [GO:0071281]	cytoplasm [GO:0005737]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to iron ion [GO:0071281]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3cela__d2a6za1__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; fungal-type vacuole membrane [GO:0000329]; Golgi membrane [GO:0000139]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]; carbohydrate derivative binding [GO:0097367]; mannose binding [GO:0005537]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]	cellulose catabolic process [GO:0030245]	endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]	extracellular region [GO:0005576]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; fungal-type vacuole membrane [GO:0000329]; Golgi membrane [GO:0000139]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of Golgi membrane [GO:0030173]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	carbohydrate derivative binding [GO:0097367]; mannose binding [GO:0005537]
d3cela__d4gwab1__1	Fungi	Metazoa	Ascomycota	Arthropoda	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; metal ion binding [GO:0046872]
d3cepa__d3ctlc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	tryptophan biosynthetic process [GO:0000162]	cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3ceva__d1wvba1__1		Metazoa	Firmicutes	Chordata	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d3ceve__d3skkb___1		Metazoa	Firmicutes	Chordata	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d3cf1b4_d3hu1a2__1	Metazoa	Metazoa	Chordata	Chordata	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d3cf1c2_d1svla___1	Metazoa		Chordata		ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	host cell nucleus [GO:0042025]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]
d3cf5b1_d1kc8d___1			Deinococcus-Thermus	Euryarchaeota	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d3cf5n1_d1vsao1__1			Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	
d3cf5o1_d1vsap1__1			Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	
d3cf5t1_d2qoxw1__1			Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	
d3cf8a__d6b7ja1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]
d3cf8d__d4zv3b1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; fatty-acyl-CoA binding [GO:0000062]; identical protein binding [GO:0042802]; long-chain fatty acyl-CoA binding [GO:0036042]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290]; protein homodimerization activity [GO:0042803]; acyl-CoA metabolic process [GO:0006637]; coenzyme A biosynthetic process [GO:0015937]; fatty acid catabolic process [GO:0009062]; long-chain fatty-acyl-CoA catabolic process [GO:0036116]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; palmitic acid biosynthetic process [GO:1900535]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	acyl-CoA metabolic process [GO:0006637]; coenzyme A biosynthetic process [GO:0015937]; fatty acid catabolic process [GO:0009062]; long-chain fatty-acyl-CoA catabolic process [GO:0036116]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; palmitic acid biosynthetic process [GO:1900535]	cytoplasm [GO:0005737]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; fatty-acyl-CoA binding [GO:0000062]; identical protein binding [GO:0042802]; long-chain fatty acyl-CoA binding [GO:0036042]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290]; protein homodimerization activity [GO:0042803]
d3cf8e__d3azam___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	hydro-lyase activity [GO:0016836]
d3cf9f__d3bjka___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]; acyl-CoA hydrolase activity [GO:0047617]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]; acyl-CoA metabolic process [GO:0006637]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	acyl-CoA metabolic process [GO:0006637]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	acyl-CoA hydrolase activity [GO:0047617]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]
d3cfba1_d1r5vc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3cfbl1_d5nbwl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3cfbl2_d3v4vn1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; cell migration [GO:0016477]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]
d3cfcl1_d2ntfl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3cfdl1_d1rv6y___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]
d3cfdl1_d2gjza2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	metal ion binding [GO:0046872]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d3cfdl2_d3hi6y1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]
d3cfea2_d5fuzl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3cfel1_d2oz4l2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3cfif1_d1q72h1__1			Proteobacteria		integral component of membrane [GO:0016021]; type II protein secretion system complex [GO:0015627]; protein secretion by the type II secretion system [GO:0015628]		protein secretion by the type II secretion system [GO:0015628]		integral component of membrane [GO:0016021]; type II protein secretion system complex [GO:0015627]			
d3cfja1_d2dbll2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cfjc1_d1bbdl1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	immune response [GO:0006955]; immunoglobulin production [GO:0002377]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d3cfjd1_d3cfba2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cfje1_d3nigf1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3cfjf1_d1a3ll1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cfjf1_d3ejzf2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cfjf2_d2pyfa2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cfjh1_d1ffna1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3cfjh2_d2h2sf1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3cfka1_d2v7hh3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cfka2_d3cvhl1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3cfkb2_d5iueb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3cfkb2_d5jdeb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d3cfkc1_d2a1wm1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	metal ion binding [GO:0046872]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d3cfkc1_d4wfhf2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]; identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]; cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]
d3cfkd1_d3s7gc2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cfkd2_d5jqda1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3cfkg2_d4k07b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d3cfkh1_d1tiua___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d3cfkh2_d2v7hh3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cfkk1_d1jl4d1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3cfkm1_d4l8ba2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3cfkm2_d1igyd1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cfko1_d1yjdc1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; SH3/SH2 adaptor activity [GO:0005070]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cytokine biosynthetic process [GO:0042089]; humoral immune response [GO:0006959]; immune system process [GO:0002376]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of viral genome replication [GO:0045070]; regulation of defense response to virus by virus [GO:0050690]; regulation of regulatory T cell differentiation [GO:0045589]; regulatory T cell differentiation [GO:0045066]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cytokine biosynthetic process [GO:0042089]; humoral immune response [GO:0006959]; immune system process [GO:0002376]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of viral genome replication [GO:0045070]; regulation of defense response to virus by virus [GO:0050690]; regulation of regulatory T cell differentiation [GO:0045589]; regulatory T cell differentiation [GO:0045066]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; SH3/SH2 adaptor activity [GO:0005070]
d3cfoa1_d1jlfa1__1					3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3cg0a1_d3myya___1			Proteobacteria	Proteobacteria	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d3cg0d1_d4hnqa1__1			Proteobacteria	Proteobacteria	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]				metal ion binding [GO:0046872]
d3cgaa__d1xfyq1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d3cgta2_d1vepa1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3cgta4_d3wbaa___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; scopolin beta-glucosidase activity [GO:0102483]
d3ch1a2_d4tsal1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3ch1j2_d3k2ul1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	proteolysis [GO:0006508]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3chbd__d1lt4f___1			Proteobacteria	Proteobacteria	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	killing of cells of other organism [GO:0031640]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d3chbh__d1b44f___1			Proteobacteria	Proteobacteria	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]		catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d3chma1_d1elwb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	COP9 signalosome [GO:0008180]; cytosol [GO:0005829]; COP9 signalosome assembly [GO:0010387]; multicellular organism development [GO:0007275]; protein deneddylation [GO:0000338]; red, far-red light phototransduction [GO:0009585]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; cellular response to interleukin-7 [GO:0098761]	COP9 signalosome assembly [GO:0010387]; multicellular organism development [GO:0007275]; protein deneddylation [GO:0000338]; red, far-red light phototransduction [GO:0009585]	cellular response to interleukin-7 [GO:0098761]	COP9 signalosome [GO:0008180]; cytosol [GO:0005829]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		chaperone binding [GO:0051087]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]
d3choa3_d4h49d1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3chpa1_d1y6ia1__1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	tetrapyrrole binding [GO:0046906]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]		aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	tetrapyrrole binding [GO:0046906]
d3chqa1_d2pkgb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	chromosome, centromeric region [GO:0000775]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; protein phosphatase regulator activity [GO:0019888]; protein serine/threonine phosphatase activity [GO:0004722]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; chromosome segregation [GO:0007059]; ciliary basal body-plasma membrane docking [GO:0097711]; female meiotic nuclear division [GO:0007143]; G2/M transition of mitotic cell cycle [GO:0000086]; inactivation of MAPK activity [GO:0000188]; meiotic sister chromatid cohesion, centromeric [GO:0051754]; meiotic spindle elongation [GO:0051232]; mitotic nuclear envelope reassembly [GO:0007084]; mitotic sister chromatid separation [GO:0051306]; negative regulation of cell growth [GO:0030308]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; protein-containing complex assembly [GO:0065003]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of growth [GO:0040008]; regulation of meiotic cell cycle process involved in oocyte maturation [GO:1903538]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; chromosome segregation [GO:0007059]; ciliary basal body-plasma membrane docking [GO:0097711]; female meiotic nuclear division [GO:0007143]; G2/M transition of mitotic cell cycle [GO:0000086]; inactivation of MAPK activity [GO:0000188]; meiotic sister chromatid cohesion, centromeric [GO:0051754]; meiotic spindle elongation [GO:0051232]; mitotic nuclear envelope reassembly [GO:0007084]; mitotic sister chromatid separation [GO:0051306]; negative regulation of cell growth [GO:0030308]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein-containing complex assembly [GO:0065003]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of growth [GO:0040008]; regulation of meiotic cell cycle process involved in oocyte maturation [GO:1903538]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	chromosome, centromeric region [GO:0000775]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; protein phosphatase regulator activity [GO:0019888]; protein serine/threonine phosphatase activity [GO:0004722]
d3chqa3_d1lnbe___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3chra3_d2x95a___1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; sperm individualization [GO:0007291]; spermatid nucleus differentiation [GO:0007289]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	metamorphosis [GO:0007552]; proteolysis [GO:0006508]; response to symbiotic bacterium [GO:0009609]; spermatid nucleus differentiation [GO:0007289]; sperm individualization [GO:0007291]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; exopeptidase activity [GO:0008238]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]
d3chsa3_d1ktoa___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3ci1a1_d2zhzb___1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]; cobalamin biosynthetic process [GO:0009236]	ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]; cobalamin biosynthetic process [GO:0009236]	cobalamin biosynthetic process [GO:0009236]	cobalamin biosynthetic process [GO:0009236]			ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]	ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]
d3ci3a1_d3gaha___1			Firmicutes	Firmicutes	ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]; cobalamin biosynthetic process [GO:0009236]	ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]; cobalamin biosynthetic process [GO:0009236]	cobalamin biosynthetic process [GO:0009236]	cobalamin biosynthetic process [GO:0009236]			ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]	ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]
d3ci4a1_d1noga___1			Firmicutes	Euryarchaeota	ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]; cobalamin biosynthetic process [GO:0009236]		cobalamin biosynthetic process [GO:0009236]				ATP binding [GO:0005524]; cob(I)yrinic acid a,c-diamide adenosyltransferase activity [GO:0008817]	
d3ci5a2_d1ijjb2__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3ci5a2_d3wxjb2__1	Metazoa		Chordata		actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]		actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d3ciba__d1msna___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3cica__d1fmba___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d3cida__d5p2fa___1	Metazoa	Fungi	Chordata	Ascomycota	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]
d3cidb__d5p41a___1	Metazoa	Fungi	Chordata	Ascomycota	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]
d3ciia1_d1zluk2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ciib1_d1pg7z1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ciid2_d4i5bd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d3ciie1_d1qa9b___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	anchored component of plasma membrane [GO:0046658]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; membrane raft polarization [GO:0001766]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of T cell differentiation [GO:0045580]; T cell activation [GO:0042110]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	apoptotic process [GO:0006915]; cell-cell adhesion [GO:0098609]; cell surface receptor signaling pathway [GO:0007166]; heterotypic cell-cell adhesion [GO:0034113]; leukocyte migration [GO:0050900]; membrane raft polarization [GO:0001766]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of myeloid dendritic cell activation [GO:0030887]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of T cell differentiation [GO:0045580]; T cell activation [GO:0042110]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	anchored component of plasma membrane [GO:0046658]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; cytoplasmic side of plasma membrane [GO:0009898]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]
d3ciig1_d1rdl2___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]
d3ciii1_d4n38c___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d3cika1_d3c7kd___1	Metazoa	Metazoa	Chordata	Chordata	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; membrane raft [GO:0045121]; GTPase activator activity [GO:0005096]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; membrane raft [GO:0045121]	G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]	GTPase activator activity [GO:0005096]
d3cikb__d2ce9c2__1	Metazoa	Metazoa	Chordata	Chordata	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	beta-catenin-TCF complex [GO:1990907]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; identical protein binding [GO:0042802]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; animal organ morphogenesis [GO:0009887]; beta-catenin-TCF complex assembly [GO:1904837]; multicellular organism development [GO:0007275]; negative regulation of anoikis [GO:2000811]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	animal organ morphogenesis [GO:0009887]; beta-catenin-TCF complex assembly [GO:1904837]; multicellular organism development [GO:0007275]; negative regulation of anoikis [GO:2000811]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]	beta-catenin-TCF complex [GO:1990907]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]	identical protein binding [GO:0042802]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]
d3cikb__d2h6kb___1	Metazoa	Metazoa	Chordata	Chordata	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]
d3cima1_d5djbh___1			Cyanobacteria	Proteobacteria								
d3cipg2_d2fghb2__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d3ciqa__d1n5ad1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ciqa__d3qjhd1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ciqc__d2vira1__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]
d3ciqd__d2oqjk1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ciqe__d4rzcc___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ciqf__d2xfxa2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ciqi__d1igfm2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ciqi__d2j1kk___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3ciqk__d4fp8o1__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]
d3ciql__d1nsnl1__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; membrane [GO:0016020]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3cirm1_d2bs4d1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d3cirn1_d2wp9f2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d3cirn2_d2bs4b2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d3cirn2_d4zhpa1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	chloroplast [GO:0009507]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	chloroplast [GO:0009507]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3cjcg1_d3l50a1__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cortical patch [GO:0030479]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; Arp2/3 complex binding [GO:0071933]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; protein kinase inhibitor activity [GO:0004860]; actin filament debranching [GO:0071846]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; neutrophil degranulation [GO:0043312]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament debranching [GO:0071846]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; neutrophil degranulation [GO:0043312]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cortical patch [GO:0030479]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; Arp2/3 complex binding [GO:0071933]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; protein kinase inhibitor activity [GO:0004860]
d3cjia__d4rqpk___1					host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=3 icosahedral viral capsid [GO:0039617]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; Lys48-specific deubiquitinase activity [GO:1990380]; Lys63-specific deubiquitinase activity [GO:0061578]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host RIG-I signaling pathway [GO:0039538]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host TRAF activity [GO:0039547]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host RIG-I signaling pathway [GO:0039538]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host TRAF activity [GO:0039547]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=3 icosahedral viral capsid [GO:0039617]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; Lys48-specific deubiquitinase activity [GO:1990380]; Lys63-specific deubiquitinase activity [GO:0061578]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3cjka1_d1cpza___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper ion binding [GO:0005507]; copper-dependent protein binding [GO:0032767]; metallochaperone activity [GO:0016530]; cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; metal ion transport [GO:0030001]	cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	metal ion transport [GO:0030001]	cell [GO:0005623]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; metallochaperone activity [GO:0016530]	copper ion binding [GO:0005507]
d3cjkb1_d2xmjb___1	Metazoa		Chordata	Cyanobacteria	cell [GO:0005623]; cytosol [GO:0005829]; ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper ion binding [GO:0005507]; copper-dependent protein binding [GO:0032767]; metallochaperone activity [GO:0016530]; cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	copper ion binding [GO:0005507]; metal ion transport [GO:0030001]	cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	metal ion transport [GO:0030001]	cell [GO:0005623]; cytosol [GO:0005829]		ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; metallochaperone activity [GO:0016530]	copper ion binding [GO:0005507]
d3cjtn2_d2qami2__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; protein methyltransferase activity [GO:0008276]				cytoplasm [GO:0005737]		protein methyltransferase activity [GO:0008276]	
d3ckia__d2oy4a___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3cksa1_d1n3rb___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d3cksa2_d5m98g1__1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d3ckua1_d3i2ba___1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	urate oxidase activity [GO:0004846]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d3ckua2_d4ntkb___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	queuosine biosynthetic process [GO:0008616]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d3ckya1_d3vphb1__1			Firmicutes	Deinococcus-Thermus	2-hydroxymethylglutarate dehydrogenase activity [GO:0043718]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; cofactor catabolic process [GO:0051187]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cofactor catabolic process [GO:0051187]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	2-hydroxymethylglutarate dehydrogenase activity [GO:0043718]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	L-lactate dehydrogenase activity [GO:0004459]
d3ckya2_d1lsja1__1		Metazoa	Firmicutes	Chordata	2-hydroxymethylglutarate dehydrogenase activity [GO:0043718]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; cofactor catabolic process [GO:0051187]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	cofactor catabolic process [GO:0051187]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	2-hydroxymethylglutarate dehydrogenase activity [GO:0043718]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d3ckyb1_d2x22b___1			Firmicutes	Actinobacteria	2-hydroxymethylglutarate dehydrogenase activity [GO:0043718]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; cofactor catabolic process [GO:0051187]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cofactor catabolic process [GO:0051187]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]	2-hydroxymethylglutarate dehydrogenase activity [GO:0043718]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d3ckyd2_d1f12b1__1		Metazoa	Firmicutes	Chordata	2-hydroxymethylglutarate dehydrogenase activity [GO:0043718]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; cofactor catabolic process [GO:0051187]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	cofactor catabolic process [GO:0051187]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	2-hydroxymethylglutarate dehydrogenase activity [GO:0043718]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d3cl1b__d1runb2__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3cl2a__d1inya___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3cl2b__d2bata___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3cl2d__d4qn5b___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3cl2e__d4h52a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3cl6a__d1w1a1___1			Proteobacteria	Firmicutes	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]; sporulation resulting in formation of a cellular spore [GO:0030435]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]; sporulation resulting in formation of a cellular spore [GO:0030435]			hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]
d3cl8a__d2y8ua___1		Fungi	Proteobacteria	Ascomycota	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]	chitin deacetylase activity [GO:0004099]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]	chitin deacetylase activity [GO:0004099]
d3claa__d1l5aa2__1			Proteobacteria	Proteobacteria	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; enterobactin synthetase complex [GO:0009366]; 2,3-dihydroxybenzoate-serine ligase activity [GO:0047527]; acid-ammonia (or amide) ligase activity [GO:0016880]; phosphopantetheine binding [GO:0031177]; amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; enterobactin biosynthetic process [GO:0009239]; secondary metabolite biosynthetic process [GO:0044550]; siderophore biosynthetic process [GO:0019290]	response to antibiotic [GO:0046677]	amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; enterobactin biosynthetic process [GO:0009239]; secondary metabolite biosynthetic process [GO:0044550]; siderophore biosynthetic process [GO:0019290]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; enterobactin synthetase complex [GO:0009366]	chloramphenicol O-acetyltransferase activity [GO:0008811]	2,3-dihydroxybenzoate-serine ligase activity [GO:0047527]; acid-ammonia (or amide) ligase activity [GO:0016880]; phosphopantetheine binding [GO:0031177]
d3clel1_d5vvfl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3clfl2_d4uu9b___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d3clpa__d2k0ga1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]
d3clpc__d3kccb1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3clsd1_d5ol2e___1			Proteobacteria	Firmicutes	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]					electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; flavin adenine dinucleotide binding [GO:0050660]
d3cltd2_d1efpc2__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	electron transfer activity [GO:0009055]					electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	electron transfer activity [GO:0009055]
d3cltd2_d4jufd2__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3clud2_d3glse___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]	enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3cm4a1_d3qf6a___1		Metazoa	Proteobacteria	Chordata	catalytic activity [GO:0003824]; carbohydrate biosynthetic process [GO:0016051]	extracellular region [GO:0005576]	carbohydrate biosynthetic process [GO:0016051]			extracellular region [GO:0005576]	catalytic activity [GO:0003824]	
d3cmcq2_d1tvea2__1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; homoserine dehydrogenase activity [GO:0004412]; NADP binding [GO:0050661]; homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	homoserine biosynthetic process [GO:0009090]; isoleucine biosynthetic process [GO:0009097]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	homoserine dehydrogenase activity [GO:0004412]; NADP binding [GO:0050661]
d3cmcq2_d4gpd32__1		Metazoa	Firmicutes	Arthropoda	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3cmef1_d1t0kb___1			Euryarchaeota	Proteobacteria	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	translation [GO:0006412]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ribosome [GO:0005840]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3cmfa__d1sm9b___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	oxidoreductase activity [GO:0016491]; D-xylose catabolic process [GO:0042843]	androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	D-xylose catabolic process [GO:0042843]	cytosol [GO:0005829]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]	oxidoreductase activity [GO:0016491]
d3cmmd__d3x0wb1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ubiquitin activating enzyme activity [GO:0004839]; cellular response to DNA damage stimulus [GO:0006974]; protein modification by small protein conjugation [GO:0032446]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	cellular response to DNA damage stimulus [GO:0006974]; protein modification by small protein conjugation [GO:0032446]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	ATP binding [GO:0005524]; ubiquitin activating enzyme activity [GO:0004839]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d3cmoh1_d3hcvb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3cmol1_d3e3qc___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3cmoy1_d1hxme1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	transmembrane signaling receptor activity [GO:0004888]
d3cmpa__d1xcab___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3cn2b__d3do4a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3cn7a__d1ffba___1		Fungi	Proteobacteria	Ascomycota	carboxylic ester hydrolase activity [GO:0052689]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]				extracellular region [GO:0005576]	carboxylic ester hydrolase activity [GO:0052689]	cutinase activity [GO:0050525]
d3cn7b__d1cfja___1		Metazoa	Proteobacteria	Chordata	carboxylic ester hydrolase activity [GO:0052689]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]		acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	carboxylic ester hydrolase activity [GO:0052689]	acetylcholinesterase activity [GO:0003990]
d3cn7c__d4k2ad___1			Proteobacteria	Proteobacteria	carboxylic ester hydrolase activity [GO:0052689]	haloalkane dehalogenase activity [GO:0018786]					carboxylic ester hydrolase activity [GO:0052689]	haloalkane dehalogenase activity [GO:0018786]
d3cn9b__d3ls2d___1			Proteobacteria	Proteobacteria	carboxylic ester hydrolase activity [GO:0052689]	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]; formaldehyde catabolic process [GO:0046294]		formaldehyde catabolic process [GO:0046294]			carboxylic ester hydrolase activity [GO:0052689]	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]
d3cnca__d3u6xc2__1					viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]		
d3cncb__d2wbvc___1					viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	viral capsid [GO:0019028]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]		
d3cncc__d4xl8a___1					viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	viral capsid [GO:0019028]		
d3cnce__d4hemc1__1					viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]		
d3cnkb__d1qfhb2__1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]; actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]; actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]; cell motility [GO:0048870]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; phagocytosis [GO:0006909]; phototaxis [GO:0042331]; pseudopodium assembly [GO:0031269]; response to cAMP [GO:0051591]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	anterior cell cortex [GO:0061802]; cell cortex [GO:0005938]; cell leading edge [GO:0031252]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; lateral cell cortex [GO:0097575]; macropinocytic cup [GO:0070685]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; posterior cell cortex [GO:0061803]; pseudopodium [GO:0031143]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	actin filament binding [GO:0051015]; protein homodimerization activity [GO:0042803]
d3cnqp1_d1ayea2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; vacuole [GO:0005773]; carboxypeptidase activity [GO:0004180]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; protein catabolic process in the vacuole [GO:0007039]; proteolysis [GO:0006508]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	protein catabolic process in the vacuole [GO:0007039]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; vacuole [GO:0005773]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	carboxypeptidase activity [GO:0004180]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d3cnqs__d1s2nb___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3co1a1_d1vkab___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; midbody [GO:0030496]; mitotic spindle astral microtubule end [GO:1905721]; perinuclear region of cytoplasm [GO:0048471]; spindle midzone [GO:0051233]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; cell division [GO:0051301]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; cell division [GO:0051301]; cell migration [GO:0016477]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of cell migration [GO:0030335]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	cell division [GO:0051301]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	cell division [GO:0051301]; cell migration [GO:0016477]; ciliary basal body-plasma membrane docking [GO:0097711]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of cell migration [GO:0030335]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of microtubule polymerization [GO:0031116]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; midbody [GO:0030496]; mitotic spindle astral microtubule end [GO:1905721]; perinuclear region of cytoplasm [GO:0048471]; spindle midzone [GO:0051233]	cell projection membrane [GO:0031253]; centrosome [GO:0005813]; cortical microtubule cytoskeleton [GO:0030981]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule [GO:0005874]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; mitotic spindle astral microtubule end [GO:1905721]; spindle midzone [GO:0051233]	identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d3co2b__d5c6ca___1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; cofactor metabolic process [GO:0051186]; negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]		cofactor metabolic process [GO:0051186]; negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]
d3co2d__d1zrca2__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3co7f__d1ka8b___1	Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein phosphatase 2A binding [GO:0051721]; sequence-specific DNA binding [GO:0043565]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; blood vessel development [GO:0001568]; cellular glucose homeostasis [GO:0001678]; cellular response to cold [GO:0070417]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to nitric oxide [GO:0071732]; cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; cytokine-mediated signaling pathway [GO:0019221]; enamel mineralization [GO:0070166]; endocrine pancreas development [GO:0031018]; energy homeostasis [GO:0097009]; fat cell differentiation [GO:0045444]; glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter [GO:0035947]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to fluoride [GO:1902617]; temperature homeostasis [GO:0001659]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; zinc ion binding [GO:0008270]	apoptotic process [GO:0006915]; autophagy [GO:0006914]; blood vessel development [GO:0001568]; cellular glucose homeostasis [GO:0001678]; cellular response to cold [GO:0070417]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to nitric oxide [GO:0071732]; cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; cytokine-mediated signaling pathway [GO:0019221]; enamel mineralization [GO:0070166]; endocrine pancreas development [GO:0031018]; energy homeostasis [GO:0097009]; fat cell differentiation [GO:0045444]; glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuronal stem cell population maintenance [GO:0097150]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein acetylation [GO:0006473]; regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter [GO:0035947]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to fluoride [GO:1902617]; temperature homeostasis [GO:0001659]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; protein phosphatase 2A binding [GO:0051721]; sequence-specific DNA binding [GO:0043565]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; zinc ion binding [GO:0008270]
d3cotb__d1r38b___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	oxidoreductase activity [GO:0016491]; D-xylose catabolic process [GO:0042843]	androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	D-xylose catabolic process [GO:0042843]	cytosol [GO:0005829]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]	oxidoreductase activity [GO:0016491]
d3cowa__d1xjqa2__1		Metazoa	Actinobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]; beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d3coza__d4yp6a1__1			Actinobacteria	Euryarchaeota	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]; beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; NAD biosynthetic process [GO:0009435]	beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	NAD biosynthetic process [GO:0009435]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]
d3cp4a__d4ktka___1			Proteobacteria		cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	
d3cpaa__d2pj9a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d3cpld__d1fail1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3cq5a__d4zsyc___1		Metazoa	Actinobacteria	Chordata	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	histidine biosynthetic process [GO:0000105]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]		4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]	(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]
d3cq5b__d1tasb___1		Metazoa	Actinobacteria	Chordata	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	histidine biosynthetic process [GO:0000105]	2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]	kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]
d3cq5c__d5u21d1__1			Actinobacteria	Proteobacteria	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	transaminase activity [GO:0008483]	histidine biosynthetic process [GO:0000105]				histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]	transaminase activity [GO:0008483]
d3cqdb__d1v1aa___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; 6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphofructokinase activity [GO:0008443]; tagatose-6-phosphate kinase activity [GO:0009024]; cellular response to DNA damage stimulus [GO:0006974]; glycolytic process [GO:0006096]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]; phosphorylation [GO:0016310]	cellular response to DNA damage stimulus [GO:0006974]; glycolytic process [GO:0006096]	phosphorylation [GO:0016310]	cytosol [GO:0005829]		6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphofructokinase activity [GO:0008443]; tagatose-6-phosphate kinase activity [GO:0009024]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]
d3cqla__d2z37a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	vacuole [GO:0005773]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	vacuole [GO:0005773]		chitinase activity [GO:0004568]; chitin binding [GO:0008061]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d3cqlb__d4dygb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	vacuole [GO:0005773]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]; polysaccharide catabolic process [GO:0000272]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response [GO:0006952]; polysaccharide catabolic process [GO:0000272]	cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]; defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]; polysaccharide catabolic process [GO:0000272]	vacuole [GO:0005773]	extracellular region [GO:0005576]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d3cqoa2_d3sepb1__1	Metazoa		Chordata	Proteobacteria	metal ion binding [GO:0046872]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3cqob1_d3czja1__1	Metazoa		Chordata	Proteobacteria	metal ion binding [GO:0046872]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3cqob2_d3vd5c1__1	Metazoa		Chordata	Proteobacteria	metal ion binding [GO:0046872]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3cqoc1_d1oh4a___1	Metazoa		Chordata	Thermotogae	metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3cqoc2_d1jz5c3__1	Metazoa		Chordata	Proteobacteria	metal ion binding [GO:0046872]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3cqpa__d4b3ei___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d3cqpd__d4rvpe___1	Metazoa	Viridiplantae	Chordata	Streptophyta	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]		chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3cqxa2_d3fzla1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; chaperone complex [GO:0101031]; dendrite [GO:0030425]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; tau protein binding [GO:0048156]; ubiquitin protein ligase binding [GO:0031625]; negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein processing [GO:0010954]; protein metabolic process [GO:0019538]; protein stabilization [GO:0050821]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	negative regulation of protein binding [GO:0032091]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein processing [GO:0010954]; protein metabolic process [GO:0019538]; protein stabilization [GO:0050821]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	axon [GO:0030424]; chaperone complex [GO:0101031]; dendrite [GO:0030425]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; tau protein binding [GO:0048156]; ubiquitin protein ligase binding [GO:0031625]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3cr4x__d1tnpa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	troponin complex [GO:0005861]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]
d3cr5x__d2prua___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d3cr5x__d5wc5r1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d3cr6a__d3hwdc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d3cr9a1_d3ttma___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	periplasmic space [GO:0042597]; putrescine binding [GO:0019810]; polyamine transport [GO:0015846]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	polyamine transport [GO:0015846]	extracellular space [GO:0005615]; specific granule [GO:0042581]	periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]	putrescine binding [GO:0019810]
d3crda__d4rhwe___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; death domain binding [GO:0070513]; protease binding [GO:0002020]; protein binding, bridging [GO:0030674]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; regulation of apoptotic process [GO:0042981]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; regulation of apoptotic process [GO:0042981]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	death domain binding [GO:0070513]; protease binding [GO:0002020]; protein binding, bridging [GO:0030674]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d3crea1_d2bcmb___1			Proteobacteria	Proteobacteria		pilus [GO:0009289]				pilus [GO:0009289]		
d3crea1_d5l4vc___1			Proteobacteria	Proteobacteria		host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d3crgb1_d1qqla___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	extracellular space [GO:0005615]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; type 2 fibroblast growth factor receptor binding [GO:0005111]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; ovarian follicle development [GO:0001541]; phosphatidylcholine biosynthetic process [GO:0006656]; phospholipid biosynthetic process [GO:0008654]; positive regulation of cell division [GO:0051781]; positive regulation of epithelial cell proliferation [GO:0050679]; surfactant homeostasis [GO:0043129]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; ovarian follicle development [GO:0001541]; phosphatidylcholine biosynthetic process [GO:0006656]; phospholipid biosynthetic process [GO:0008654]; positive regulation of cell division [GO:0051781]; positive regulation of epithelial cell proliferation [GO:0050679]; surfactant homeostasis [GO:0043129]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	growth factor activity [GO:0008083]; heparin binding [GO:0008201]; type 2 fibroblast growth factor receptor binding [GO:0005111]
d3crha1_d1ev2a___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3cria1_d4fgfa___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]
d3crkb1_d4e01a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254]; ATP binding [GO:0005524]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740]; cellular response to nutrient [GO:0031670]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrion [GO:0005739]; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity [GO:0047323]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	cellular response to nutrient [GO:0031670]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]	branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740]	[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity [GO:0047323]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]
d3crlb1_d4h81a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254]; ATP binding [GO:0005524]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; protein-containing complex binding [GO:0044877]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740]; cellular response to nutrient [GO:0031670]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrion [GO:0005739]; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity [GO:0047323]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	cellular response to nutrient [GO:0031670]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]	branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; pyruvate dehydrogenase complex [GO:0045254]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740]	[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity [GO:0047323]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]
d3crol__d2lyqa___1				Firmicutes	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]	regulation of transcription, DNA-templated [GO:0006355]				DNA binding [GO:0003677]	DNA binding [GO:0003677]
d3crta2_d2pbjb1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]		cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]		cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]	glutathione transferase activity [GO:0004364]	electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]
d3crza2_d1gvha3__1			Proteobacteria	Proteobacteria	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]; cellular response to oxidative stress [GO:0034599]; heme catabolic process [GO:0042167]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; heme binding [GO:0020037]; hydroperoxide reductase activity [GO:0032843]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular response to nitrosative stress [GO:0071500]; nitric oxide catabolic process [GO:0046210]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	cellular response to oxidative stress [GO:0034599]; heme catabolic process [GO:0042167]	cellular response to nitrosative stress [GO:0071500]; nitric oxide catabolic process [GO:0046210]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]		cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; heme binding [GO:0020037]; hydroperoxide reductase activity [GO:0032843]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3crza2_d5gv7a2__1		Metazoa	Proteobacteria	Chordata	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]; cellular response to oxidative stress [GO:0034599]; heme catabolic process [GO:0042167]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]	cellular response to oxidative stress [GO:0034599]; heme catabolic process [GO:0042167]	cholesterol biosynthetic process [GO:0006695]		endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d3cs3a__d3kg2c1__1		Metazoa	Firmicutes	Chordata	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	regulation of transcription, DNA-templated [GO:0006355]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	DNA binding [GO:0003677]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3cs4a__d5ufoa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]; calcitriol binding [GO:1902098]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; lithocholic acid binding [GO:1902121]; lithocholic acid receptor activity [GO:0038186]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; vitamin D binding [GO:0005499]; zinc ion binding [GO:0008270]; animal organ morphogenesis [GO:0009887]; bile acid signaling pathway [GO:0038183]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cell morphogenesis [GO:0000902]; cellular calcium ion homeostasis [GO:0006874]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; decidualization [GO:0046697]; intestinal absorption [GO:0050892]; lactation [GO:0007595]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; mammary gland branching involved in pregnancy [GO:0060745]; multicellular organism development [GO:0007275]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process involved in mammary gland involution [GO:0060058]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vitamin D 24-hydroxylase activity [GO:0010980]; regulation of calcidiol 1-monooxygenase activity [GO:0060558]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; transcription initiation from RNA polymerase II promoter [GO:0006367]; vitamin D metabolic process [GO:0042359]; vitamin D receptor signaling pathway [GO:0070561]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	animal organ morphogenesis [GO:0009887]; bile acid signaling pathway [GO:0038183]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cell morphogenesis [GO:0000902]; cellular calcium ion homeostasis [GO:0006874]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; decidualization [GO:0046697]; intestinal absorption [GO:0050892]; lactation [GO:0007595]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; mammary gland branching involved in pregnancy [GO:0060745]; multicellular organism development [GO:0007275]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process involved in mammary gland involution [GO:0060058]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vitamin D 24-hydroxylase activity [GO:0010980]; regulation of calcidiol 1-monooxygenase activity [GO:0060558]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; transcription initiation from RNA polymerase II promoter [GO:0006367]; vitamin D metabolic process [GO:0042359]; vitamin D receptor signaling pathway [GO:0070561]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	calcitriol binding [GO:1902098]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; lithocholic acid binding [GO:1902121]; lithocholic acid receptor activity [GO:0038186]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; vitamin D binding [GO:0005499]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d3cs6a__d2ewpc___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]; calcitriol binding [GO:1902098]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; lithocholic acid binding [GO:1902121]; lithocholic acid receptor activity [GO:0038186]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; vitamin D binding [GO:0005499]; zinc ion binding [GO:0008270]; animal organ morphogenesis [GO:0009887]; bile acid signaling pathway [GO:0038183]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cell morphogenesis [GO:0000902]; cellular calcium ion homeostasis [GO:0006874]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; decidualization [GO:0046697]; intestinal absorption [GO:0050892]; lactation [GO:0007595]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; mammary gland branching involved in pregnancy [GO:0060745]; multicellular organism development [GO:0007275]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process involved in mammary gland involution [GO:0060058]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vitamin D 24-hydroxylase activity [GO:0010980]; regulation of calcidiol 1-monooxygenase activity [GO:0060558]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; transcription initiation from RNA polymerase II promoter [GO:0006367]; vitamin D metabolic process [GO:0042359]; vitamin D receptor signaling pathway [GO:0070561]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; AF-2 domain binding [GO:0050682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid receptor signaling pathway [GO:0048384]; transcription initiation from RNA polymerase II promoter [GO:0006367]	animal organ morphogenesis [GO:0009887]; bile acid signaling pathway [GO:0038183]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cell morphogenesis [GO:0000902]; cellular calcium ion homeostasis [GO:0006874]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; decidualization [GO:0046697]; intestinal absorption [GO:0050892]; lactation [GO:0007595]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; mammary gland branching involved in pregnancy [GO:0060745]; multicellular organism development [GO:0007275]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process involved in mammary gland involution [GO:0060058]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vitamin D 24-hydroxylase activity [GO:0010980]; regulation of calcidiol 1-monooxygenase activity [GO:0060558]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; transcription initiation from RNA polymerase II promoter [GO:0006367]; vitamin D metabolic process [GO:0042359]; vitamin D receptor signaling pathway [GO:0070561]	positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid receptor signaling pathway [GO:0048384]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cell [GO:0005623]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]	calcitriol binding [GO:1902098]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; lithocholic acid binding [GO:1902121]; lithocholic acid receptor activity [GO:0038186]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; vitamin D binding [GO:0005499]; zinc ion binding [GO:0008270]	AF-2 domain binding [GO:0050682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor activity [GO:0004879]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]
d3cs7a__d1gbla___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d3csha1_d4gcia2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	transferase activity [GO:0016740]
d3cshb1_d1glpa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]
d3csib1_d1k3yb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3csib1_d2on5f2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	transferase activity [GO:0016740]
d3csic1_d2hqtr___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]; enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]; positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]
d3csid1_d3hjma2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3csja2_d2vcwa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d3csjb1_d1gumb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ct2a2_d4il0a2__1			Proteobacteria	Proteobacteria	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; cellular catabolic process [GO:0044248]	cellular amino acid catabolic process [GO:0009063]	cellular amino acid catabolic process [GO:0009063]; cellular catabolic process [GO:0044248]			chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]
d3ct2b2_d1te6b1__1		Metazoa	Proteobacteria	Chordata	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cellular amino acid catabolic process [GO:0009063]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3ct7a__d3sy5a___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]		allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3ct7d__d1a53a___1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]		allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]
d3ct7f__d2flig___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]		allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3ctaa1_d1p4ab1__1			Euryarchaeota	Firmicutes	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; riboflavin kinase activity [GO:0008531]; FMN biosynthetic process [GO:0009398]; regulation of transcription, DNA-templated [GO:0006355]; riboflavin biosynthetic process [GO:0009231]	DNA binding [GO:0003677]; negative regulation of purine nucleobase metabolic process [GO:0045982]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleoside metabolic process [GO:0009116]	FMN biosynthetic process [GO:0009398]; regulation of transcription, DNA-templated [GO:0006355]; riboflavin biosynthetic process [GO:0009231]	negative regulation of purine nucleobase metabolic process [GO:0045982]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleoside metabolic process [GO:0009116]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; riboflavin kinase activity [GO:0008531]	DNA binding [GO:0003677]
d3ctlf__d3femc___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	cytosol [GO:0005829]	glutaminase complex [GO:1903600]	allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3ctna__d3pala___1	Metazoa	Metazoa	Chordata	Chordata	troponin complex [GO:0005861]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]; calcium ion binding [GO:0005509]	regulation of muscle contraction [GO:0006937]; skeletal muscle contraction [GO:0003009]		troponin complex [GO:0005861]	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]	actin filament binding [GO:0051015]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]
d3ctod__d2a6qa1__1			Actinobacteria	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	endoribonuclease activity [GO:0004521]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; mRNA catabolic process [GO:0006402]; mRNA cleavage involved in gene silencing [GO:0098795]; negative regulation of translational initiation [GO:0045947]; RNA catabolic process [GO:0006401]; single-species biofilm formation [GO:0044010]	regulation of transcription, DNA-templated [GO:0006355]	mRNA catabolic process [GO:0006402]; mRNA cleavage involved in gene silencing [GO:0098795]; negative regulation of translational initiation [GO:0045947]; RNA catabolic process [GO:0006401]; single-species biofilm formation [GO:0044010]			DNA binding [GO:0003677]	endoribonuclease activity [GO:0004521]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]
d3ctpb__d5kwsa___1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	metal ion binding [GO:0046872]	regulation of transcription, DNA-templated [GO:0006355]				DNA binding [GO:0003677]	metal ion binding [GO:0046872]
d3ctta2_d3ac0b1__1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	cellulose catabolic process [GO:0030245]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]		amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3ctta3_d1xsjc3__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	carbohydrate metabolic process [GO:0005975]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]		amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d3cu4a__d1hcmb1__1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]				periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d3cu5b1_d1jlka___1			Firmicutes	Cyanobacteria	DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]			DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	
d3cu7a5_d2a73b2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d3cu7b4_d1edya___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	extracellular space [GO:0005615]; brain-derived neurotrophic factor binding [GO:0048403]; endopeptidase inhibitor activity [GO:0004866]; nerve growth factor binding [GO:0048406]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; serine-type endopeptidase inhibitor activity [GO:0004867]; embryo implantation [GO:0007566]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	embryo implantation [GO:0007566]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	extracellular space [GO:0005615]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]	brain-derived neurotrophic factor binding [GO:0048403]; endopeptidase inhibitor activity [GO:0004866]; nerve growth factor binding [GO:0048406]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; serine-type endopeptidase inhibitor activity [GO:0004867]
d3cu7be_d2goxc1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d3cuha__d2xucb1__1		Fungi	Actinobacteria	Ascomycota	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	anchored component of membrane [GO:0031225]; cell wall [GO:0005618]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		anchored component of membrane [GO:0031225]; cell wall [GO:0005618]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d3cuia__d3mv113__1			Actinobacteria	Proteobacteria	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3cupa2_d3owec___1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	pathogenesis [GO:0009405]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	extracellular region [GO:0005576]		
d3cuqa1_d1wsud1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; ESCRT II complex [GO:0000814]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; structural molecule activity [GO:0005198]; endosomal transport [GO:0016197]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; selenocysteine incorporation [GO:0001514]	endosomal transport [GO:0016197]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]	selenocysteine incorporation [GO:0001514]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; ESCRT II complex [GO:0000814]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; structural molecule activity [GO:0005198]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3cv6a__d4gq0a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0072582]; 17-beta-ketosteroid reductase activity [GO:0072555]; 5alpha-androstane-3beta,17beta-diol dehydrogenase activity [GO:0047024]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; ketosteroid monooxygenase activity [GO:0047086]; lithocholic acid binding [GO:1902121]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0033764]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d3cv8a1_d1oxaa___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; vitamin D3 metabolic process [GO:0070640]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; erythromycin biosynthetic process [GO:1901115]; oxidation-reduction process [GO:0055114]	vitamin D3 metabolic process [GO:0070640]	erythromycin biosynthetic process [GO:1901115]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3cv9a1_d5x23a___1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; vitamin D3 metabolic process [GO:0070640]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; (S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]	vitamin D3 metabolic process [GO:0070640]	cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	(S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d3cvba__d3bvdb1__1			Cyanobacteria	Deinococcus-Thermus	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]			thylakoid membrane [GO:0042651]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d3cvbb__d3ryma___1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3cvca__d1ndrb2__1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3cvca__d3c75b___1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]; methylamine metabolic process [GO:0030416]		methylamine metabolic process [GO:0030416]	thylakoid membrane [GO:0042651]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]
d3cvdb__d3qqxa2__1			Cyanobacteria	Proteobacteria	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	thylakoid membrane [GO:0042651]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d3cvhr2_d2ghwd1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d3cvil1_d3h3bc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]
d3cvil2_d1cdya1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3cvsa1_d1n3aa1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]
d3cvsa1_d1p59a1__1			Proteobacteria		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	
d3cvsb1_d1kg5a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]
d3cvta1_d1wefa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]
d3cvta2_d1vokb1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3cvtb1_d1kg6a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]
d3cvtb2_d3oc3d1__1		Fungi	Proteobacteria	Microsporidia	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]
d3cvtc1_d1xqoa___1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; oxidized base lesion DNA N-glycosylase activity [GO:0000702]; base-excision repair [GO:0006284]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; oxidized base lesion DNA N-glycosylase activity [GO:0000702]
d3cvtc2_d1pcza2__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3cvtd1_d2abka___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	4 iron, 4 sulfur cluster binding [GO:0051539]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; metal ion binding [GO:0046872]; oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [GO:0000703]; base-excision repair, AP site formation [GO:0006285]; cellular response to UV [GO:0034644]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair, AP site formation [GO:0006285]; cellular response to UV [GO:0034644]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	4 iron, 4 sulfur cluster binding [GO:0051539]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]; oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [GO:0000703]
d3cvtd2_d1c9br2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3cvua1_d1iqua2__1	Metazoa		Arthropoda	Deinococcus-Thermus	nucleotide binding [GO:0000166]	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]		DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]			nucleotide binding [GO:0000166]	deoxyribodipyrimidine photo-lyase activity [GO:0003904]; DNA binding [GO:0003677]; nucleotide binding [GO:0000166]
d3cvva1_d4mlpb1__1	Metazoa	Metazoa	Arthropoda	Chordata	nucleotide binding [GO:0000166]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; FAD binding [GO:0071949]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; phosphatase binding [GO:0019902]; photoreceptor activity [GO:0009881]; protein kinase binding [GO:0019901]; single-stranded DNA binding [GO:0003697]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; protein import into nucleus [GO:0006606]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]		circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-chromophore linkage [GO:0018298]; protein import into nucleus [GO:0006606]; regulation of circadian rhythm [GO:0042752]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleotide binding [GO:0000166]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; FAD binding [GO:0071949]; kinase binding [GO:0019900]; nuclear hormone receptor binding [GO:0035257]; phosphatase binding [GO:0019902]; photoreceptor activity [GO:0009881]; protein kinase binding [GO:0019901]; single-stranded DNA binding [GO:0003697]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3cw2d1_d2nzod1__1			Crenarchaeota	Firmicutes	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]; tRNA binding [GO:0000049]; protein transport [GO:0015031]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	protein transport [GO:0015031]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	tRNA binding [GO:0000049]
d3cw2f3_d4m4sa3__1			Crenarchaeota	Crenarchaeota	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytosol [GO:0005829]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d3cw2g2_d2a19a2__1		Fungi	Crenarchaeota	Ascomycota	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 2 complex [GO:0005850]; eukaryotic translation initiation factor 2B complex [GO:0005851]; multi-eIF complex [GO:0043614]; ribosome [GO:0005840]; ribosome binding [GO:0043022]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; translational initiation [GO:0006413]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	formation of translation preinitiation complex [GO:0001731]; translational initiation [GO:0006413]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 2B complex [GO:0005851]; eukaryotic translation initiation factor 2 complex [GO:0005850]; multi-eIF complex [GO:0043614]; ribosome [GO:0005840]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	ribosome binding [GO:0043022]; translation initiation factor activity [GO:0003743]
d3cw7b1_d2noba1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]
d3cw7b2_d1qn6a1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3cw7c1_d2jg6a___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]
d3cw7c2_d1tbpa1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]; chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase II preinitiation complex assembly [GO:0051123]; RNA polymerase III preinitiation complex assembly [GO:0070898]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; RNA polymerase III preinitiation complex assembly [GO:0070898]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transposon integration [GO:0070893]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; transcription factor TFIIA complex [GO:0005672]; transcription factor TFIID complex [GO:0005669]; transcription factor TFIIIB complex [GO:0000126]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	chromatin binding [GO:0003682]; disordered domain specific binding [GO:0097718]; DNA binding, bending [GO:0008301]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase I general transcription initiation factor binding [GO:0001179]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase III general transcription initiation factor activity [GO:0000995]; RNA polymerase III regulatory region DNA binding [GO:0001016]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase I transcription regulator recruiting activity [GO:0001186]; TFIIA-class transcription factor complex binding [GO:0001092]; transcription factor binding [GO:0008134]
d3cw7d1_d1muya___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]
d3cwaa1_d1kg3a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]
d3cwab2_d1qn9a1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3cwad1_d1rrsa1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]
d3cwad1_d5an4a2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]
d3cwha__d5nhbd___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d3cwha__d5xina___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d3cwka__d4qzuc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3cwsa1_d4aiad1__1			Proteobacteria		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	
d3cwsc1_d4piia___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; oxidized base lesion DNA N-glycosylase activity [GO:0000702]; base-excision repair [GO:0006284]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; oxidized base lesion DNA N-glycosylase activity [GO:0000702]
d3cwsc2_d1qnba2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3cwta2_d1mp9b1__1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3cwtc1_d1yqka1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]
d3cwtd2_d1qnbb2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3cwua1_d1ngna___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	chromatin [GO:0000785]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; DNA binding [GO:0003677]; pyrimidine-specific mismatch base pair DNA N-glycosylase activity [GO:0008263]; cellular response to DNA damage stimulus [GO:0006974]; DNA methylation [GO:0006306]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2 DNA damage checkpoint [GO:0007095]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	cellular response to DNA damage stimulus [GO:0006974]; DNA methylation [GO:0006306]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2 DNA damage checkpoint [GO:0007095]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	chromatin [GO:0000785]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleus [GO:0005634]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA binding [GO:0003677]; pyrimidine-specific mismatch base pair DNA N-glycosylase activity [GO:0008263]
d3cwub1_d1orpa1__1			Proteobacteria		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	
d3cwuc1_d1kg4a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]
d3cwuc2_d1mp9a1__1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3cwud1_d1muda___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	4 iron, 4 sulfur cluster binding [GO:0051539]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; adenine/guanine mispair binding [GO:0035485]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; oxidized purine DNA binding [GO:0032357]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]
d3cwvb2_d1xnqi___1			Proteobacteria	Deinococcus-Thermus	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; DNA topological change [GO:0006265]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	DNA topological change [GO:0006265]	translation [GO:0006412]		ribosome [GO:0005840]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d3cx5a1_d3l70o2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d3cx5a2_d5klvb1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3cx5e1_d1g8kb___1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]
d3cx5k__d4lsvl1__1	Fungi		Ascomycota		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	structural molecule activity [GO:0005198]
d3cx5p1_d3h1he2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d3cx5v__d2ombc2__1	Fungi		Ascomycota		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d3cx9a2_d5id9a3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3cxha2_d3l73n1__1	Fungi	Metazoa	Ascomycota	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d3cxhb1_d3cx5b2__1	Fungi	Fungi	Ascomycota	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3cxhj__d1ac6b___1	Fungi	Metazoa	Ascomycota	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]			
d3cxhk__d1kxqf___1	Fungi	Metazoa	Ascomycota	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	carbohydrate catabolic process [GO:0016052]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3cxhl1_d1joec___1	Fungi		Ascomycota	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]; quorum sensing [GO:0009372]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	quorum sensing [GO:0009372]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]			iron ion binding [GO:0005506]; S-ribosylhomocysteine lyase activity [GO:0043768]
d3cxhm1_d1bccb1__1	Fungi	Metazoa	Ascomycota	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3cxhm1_d3l71o1__1	Fungi	Metazoa	Ascomycota	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d3cxva__d4egnd___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]		carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3cxxa__d4ruib1__1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d3cxya__d2p85c___1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d3cy1a__d2ij7c___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]
d3cy1a__d2y5zb___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]		carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3cy5a__d5x2ue___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3cy5b__d107ma___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3cy5c__d1nwib___1	Metazoa	Metazoa	Chordata	Mollusca	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3cyha__d1c5fa___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; lipid droplet organization [GO:0034389]; neutrophil degranulation [GO:0043312]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of viral genome replication [GO:0045069]; RNA-dependent DNA biosynthetic process [GO:0006278]; uncoating of virus [GO:0019061]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d3cyia1_d3hy2x___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]; cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]; cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]	ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]
d3cykc__d4pmeb___1		Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]		cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]		hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3cylb__d1fe7a___1	Metazoa		Chordata		extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]		arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]		extracellular region [GO:0005576]		calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]	
d3cynb1_d1tofa___1	Metazoa	Viridiplantae	Chordata	Chlorophyta	endoplasmic reticulum lumen [GO:0005788]; integral component of membrane [GO:0016021]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytoplasm [GO:0005737]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	endoplasmic reticulum lumen [GO:0005788]; integral component of membrane [GO:0016021]	cell [GO:0005623]; cytoplasm [GO:0005737]	glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]	protein disulfide oxidoreductase activity [GO:0015035]
d3cync1_d1j08b1__1	Metazoa		Chordata	Euryarchaeota	endoplasmic reticulum lumen [GO:0005788]; integral component of membrane [GO:0016021]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]	endoplasmic reticulum lumen [GO:0005788]; integral component of membrane [GO:0016021]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d3cync1_d2dmla1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; integral component of membrane [GO:0016021]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular space [GO:0005615]; melanosome [GO:0042470]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]	cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]	endoplasmic reticulum lumen [GO:0005788]; integral component of membrane [GO:0016021]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; melanosome [GO:0042470]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]	glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide isomerase activity [GO:0003756]
d3cyto__d5kaiv___1	Metazoa		Chordata	Cyanobacteria	mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; photosystem II [GO:0009523]; thylakoid membrane [GO:0042651]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]	mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; photosystem II [GO:0009523]; thylakoid membrane [GO:0042651]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d3cyua__d3mnha___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3cywa__d2whha1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3cywb__d1hosb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3cyxa__d1aidb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3cyza__d4fqta___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d3cz1b__d1ow4b1__1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d3cz1b__d2erbb___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d3cz2a__d3n7ha___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d3cz2b__d4f7fc___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]		olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]	odorant binding [GO:0005549]	dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]
d3cz4a__d3wkaa1__1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3cz5a__d1krwa___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphorelay response regulator activity [GO:0000156]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; nitrogen fixation [GO:0009399]; regulation of nitrogen utilization [GO:0006808]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; regulation of nitrogen utilization [GO:0006808]; regulation of transcription, DNA-templated [GO:0006355]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]	ATP binding [GO:0005524]; phosphorelay response regulator activity [GO:0000156]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d3cz5a__d4d6xd___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]			DNA binding [GO:0003677]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d3cz5d__d2pmcb___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]	metal ion binding [GO:0046872]
d3czja1_d2vzsb4__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3czja3_d5i2ua___1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3czja5_d2qmja1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	lactose catabolic process [GO:0005990]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	beta-galactosidase complex [GO:0009341]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]
d3czjb1_d2v4va___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate binding [GO:0030246]; galactosylceramidase activity [GO:0004336]; galactosylceramide catabolic process [GO:0006683]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	galactosylceramide catabolic process [GO:0006683]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; galactosylceramidase activity [GO:0004336]
d3czjb2_d1yq2b1__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3czjb4_d3iapa2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3czjc3_d3cuia___1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]
d3czjd1_d2votb4__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-mannosidase activity [GO:0004567]
d3czjd1_d2wo1b1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	adherens junction [GO:0005912]; axon [GO:0030424]; axon terminus [GO:0043679]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; mitochondrial outer membrane [GO:0005741]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; DH domain binding [GO:0097161]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; PH domain binding [GO:0042731]; protein kinase activity [GO:0004672]; protein tyrosine kinase binding [GO:1990782]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to amyloid-beta [GO:1904646]; cochlea development [GO:0090102]; corticospinal tract morphogenesis [GO:0021957]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; negative regulation of axon regeneration [GO:0048681]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron projection development [GO:0010977]; negative regulation of proteolysis involved in cellular protein catabolic process [GO:1903051]; nephric duct morphogenesis [GO:0072178]; neuron projection fasciculation [GO:0106030]; neuron projection guidance [GO:0097485]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of astrocyte differentiation [GO:0048710]; regulation of axonogenesis [GO:0050770]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of modification of synaptic structure [GO:1905244]; synapse pruning [GO:0098883]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	lactose catabolic process [GO:0005990]	adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to amyloid-beta [GO:1904646]; cochlea development [GO:0090102]; corticospinal tract morphogenesis [GO:0021957]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; negative regulation of axon regeneration [GO:0048681]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron projection development [GO:0010977]; negative regulation of proteolysis involved in cellular protein catabolic process [GO:1903051]; nephric duct morphogenesis [GO:0072178]; neuron projection fasciculation [GO:0106030]; neuron projection guidance [GO:0097485]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of astrocyte differentiation [GO:0048710]; regulation of axonogenesis [GO:0050770]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of modification of synaptic structure [GO:1905244]; synapse pruning [GO:0098883]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	beta-galactosidase complex [GO:0009341]	adherens junction [GO:0005912]; axon [GO:0030424]; axonal growth cone [GO:0044295]; axon terminus [GO:0043679]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; mitochondrial outer membrane [GO:0005741]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; DH domain binding [GO:0097161]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; PH domain binding [GO:0042731]; protein kinase activity [GO:0004672]; protein tyrosine kinase binding [GO:1990782]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3czjd4_d1jyzj1__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3czma2_d2e37g2__1			Apicomplexa	Deinococcus-Thermus	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d3czma2_d3hhpc2__1			Apicomplexa	Proteobacteria	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]
d3czmb1_d4iiva___1			Apicomplexa	Proteobacteria	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; nucleotide binding [GO:0000166]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]				L-lactate dehydrogenase activity [GO:0004459]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; nucleotide binding [GO:0000166]
d3czna3_d2c71a1__1	Metazoa		Arthropoda	Firmicutes	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; xylan catabolic process [GO:0045493]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	xylan catabolic process [GO:0045493]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]
d3czua__d1bhgb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]
d3d03a__d2dxlb___1			Proteobacteria	Proteobacteria	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]					3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d3d03b__d2dxla1__1			Proteobacteria	Proteobacteria	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]					3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d3d03b__d4zvza___1		Metazoa	Proteobacteria	Chordata	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]
d3d03c__d1hp1a2__1			Proteobacteria	Proteobacteria	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]		nucleotide catabolic process [GO:0009166]		outer membrane-bounded periplasmic space [GO:0030288]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]
d3d03e__d1wao12__1		Metazoa	Proteobacteria	Chordata	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]
d3d03f__d1z2wa1__1		Metazoa	Proteobacteria	Chordata	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer complex [GO:0030904]; retromer, cargo-selective complex [GO:0030906]; metal ion binding [GO:0046872]; endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]		endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]		cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer, cargo-selective complex [GO:0030906]; retromer complex [GO:0030904]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]
d3d04a__d4ncpa___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	thiolester hydrolase activity [GO:0016790]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	thiolester hydrolase activity [GO:0016790]
d3d04b__d5byug___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	
d3d04c__d3spse___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	thiolester hydrolase activity [GO:0016790]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	thiolester hydrolase activity [GO:0016790]
d3d04d__d2b3na___1			Proteobacteria		cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	
d3d0ga__d1y3ge___1	Metazoa		Chordata	Firmicutes	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]		brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3d0gb__d456ca___1	Metazoa	Metazoa	Chordata	Chordata	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d3d0ib__d3f17a___1	Metazoa	Metazoa	Chordata	Chordata	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3d0ob1_d4fr5b2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	glycolytic process [GO:0006096]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	L-lactate dehydrogenase activity [GO:0004459]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d3d0sa1_d4i02c1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3d0sa2_d1db8a4__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]		negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	
d3d0sa2_d2efwb___1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; DNA replication termination [GO:0006274]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	DNA replication termination [GO:0006274]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d3d0sb1_d4i0ab1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3d0ya__d1djyb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol phospholipase C activity [GO:0004435]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	G protein-coupled receptor signaling pathway [GO:0007186]; inositol trisphosphate biosynthetic process [GO:0032959]; lipid catabolic process [GO:0016042]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; release of sequestered calcium ion into cytosol [GO:0051209]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipid binding [GO:0005543]
d3d0za2_d5j41b2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3d10a__d3pata___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	calcium ion binding [GO:0005509]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]		calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]
d3d12b__d2fqga1__1			Negarnaviricota	Proteobacteria	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d3d18b1_d2rgsa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3d19a2_d3dbyg2__1												
d3d19b1_d3dbyq1__1												
d3d19c2_d3dbyb2__1												
d3d19e1_d3dbyc1__1												
d3d1aa__d1dxvb___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3d1aa__d3aq5b___1	Metazoa		Chordata	Ciliophora	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3d1ea2_d1iz5b2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]		3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d3d1ea3_d5momb1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d3d1eb2_d1vyji1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d3d1eb3_d4n95a2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3d1fa3_d3f1va1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3d1fb2_d3pweb3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3d1ga1_d6ap4h3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d3d1ga2_d6ap4o3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA replication [GO:0006260]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d3d1ga3_d4pnwb1__1			Proteobacteria		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]		3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	
d3d1gb3_d3k4xa6__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	nucleus [GO:0005634]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d3d1ma__d3n1qa___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]; transport vesicle [GO:0030133]; calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; laminin-1 binding [GO:0043237]; patched binding [GO:0005113]; zinc ion binding [GO:0008270]; anatomical structure development [GO:0048856]; anatomical structure formation involved in morphogenesis [GO:0048646]; androgen metabolic process [GO:0008209]; angiogenesis [GO:0001525]; animal organ formation [GO:0048645]; anterior/posterior pattern specification [GO:0009952]; apoptotic signaling pathway [GO:0097190]; artery development [GO:0060840]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; blood coagulation [GO:0007596]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bud outgrowth involved in lung branching [GO:0060447]; camera-type eye development [GO:0043010]; canonical Wnt signaling pathway [GO:0060070]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell development [GO:0048468]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cell proliferation in external granule layer [GO:0021924]; cell-cell signaling [GO:0007267]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; cerebellar granule cell precursor proliferation [GO:0021930]; commissural neuron axon guidance [GO:0071679]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; determination of left/right symmetry [GO:0007368]; developmental growth [GO:0048589]; digestive tract mesoderm development [GO:0007502]; digestive tract morphogenesis [GO:0048546]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic morphogenesis [GO:0048598]; embryonic organ development [GO:0048568]; embryonic skeletal system development [GO:0048706]; endocytosis [GO:0006897]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; epithelial-mesenchymal cell signaling [GO:0060684]; epithelial-mesenchymal signaling involved in prostate gland development [GO:0060738]; establishment of cell polarity [GO:0030010]; forebrain development [GO:0030900]; forebrain regionalization [GO:0021871]; formation of anatomical boundary [GO:0048859]; fungiform papilla development [GO:0061196]; fungiform papilla formation [GO:0061198]; fungiform papilla morphogenesis [GO:0061197]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; inner ear development [GO:0048839]; intein-mediated protein splicing [GO:0016539]; intermediate filament organization [GO:0045109]; kidney development [GO:0001822]; left lung development [GO:0060459]; limb bud formation [GO:0060174]; limb development [GO:0060173]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung lobe morphogenesis [GO:0060463]; lung morphogenesis [GO:0060425]; lung-associated mesenchyme development [GO:0060484]; lymphoid progenitor cell differentiation [GO:0002320]; male genitalia development [GO:0030539]; male genitalia morphogenesis [GO:0048808]; mesenchymal cell proliferation [GO:0010463]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal smoothened signaling pathway involved in prostate gland development [GO:0060783]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephros development [GO:0001656]; midbrain development [GO:0030901]; myoblast differentiation [GO:0045445]; myotube differentiation [GO:0014902]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of gene expression [GO:0010629]; negative regulation of kidney smooth muscle cell differentiation [GO:2000357]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of neuron death [GO:1901215]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of ureter smooth muscle cell differentiation [GO:2000062]; negative regulation of Wnt signaling pathway [GO:0030178]; negative thymic T cell selection [GO:0045060]; neural crest cell migration [GO:0001755]; neural tube formation [GO:0001841]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; odontogenesis [GO:0042476]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; osteoblast development [GO:0002076]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; polarity specification of anterior/posterior axis [GO:0009949]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of gene expression [GO:0010628]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of kidney smooth muscle cell differentiation [GO:2000358]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mesenchymal cell proliferation involved in ureter development [GO:2000729]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neurotrophin production [GO:0032901]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; positive regulation of penile erection [GO:0060406]; positive regulation of photoreceptor cell differentiation [GO:0046534]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sclerotome development [GO:0061189]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ureter smooth muscle cell differentiation [GO:2000063]; positive regulation of Wnt signaling pathway [GO:0030177]; positive thymic T cell selection [GO:0045059]; primary prostatic bud elongation [GO:0060516]; prostate epithelial cord elongation [GO:0060523]; prostate gland development [GO:0030850]; protein localization to nucleus [GO:0034504]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of gene expression [GO:0010468]; regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782]; regulation of odontogenesis [GO:0042481]; regulation of prostatic bud formation [GO:0060685]; regulation of protein localization to nucleus [GO:1900180]; regulation of proteolysis [GO:0030162]; regulation of transcription, DNA-templated [GO:0006355]; respiratory tube development [GO:0030323]; response to axon injury [GO:0048678]; response to ethanol [GO:0045471]; right lung development [GO:0060458]; roof of mouth development [GO:0060021]; salivary gland cavitation [GO:0060662]; signal transduction [GO:0007165]; skin development [GO:0043588]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; somite development [GO:0061053]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord motor neuron differentiation [GO:0021522]; stem cell development [GO:0048864]; striated muscle cell differentiation [GO:0051146]; striated muscle tissue development [GO:0014706]; T cell differentiation in thymus [GO:0033077]; telencephalon regionalization [GO:0021978]; thalamus development [GO:0021794]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue development [GO:0043586]; tongue morphogenesis [GO:0043587]; trachea development [GO:0060438]; trachea morphogenesis [GO:0060439]; tracheoesophageal septum formation [GO:1905327]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; ventral spinal cord interneuron specification [GO:0021521]; zona limitans intrathalamica formation [GO:0022006]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anterior/posterior pattern specification [GO:0009952]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; cerebral cortex development [GO:0021987]; embryonic body morphogenesis [GO:0010172]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; lens development in camera-type eye [GO:0002088]; myoblast fusion [GO:0007520]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of protein binding [GO:0043393]; skeletal muscle satellite cell differentiation [GO:0014816]; smoothened signaling pathway [GO:0007224]	anatomical structure development [GO:0048856]; anatomical structure formation involved in morphogenesis [GO:0048646]; androgen metabolic process [GO:0008209]; angiogenesis [GO:0001525]; animal organ formation [GO:0048645]; anterior/posterior pattern specification [GO:0009952]; apoptotic signaling pathway [GO:0097190]; artery development [GO:0060840]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; blood coagulation [GO:0007596]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bud outgrowth involved in lung branching [GO:0060447]; camera-type eye development [GO:0043010]; canonical Wnt signaling pathway [GO:0060070]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell-cell signaling [GO:0007267]; cell development [GO:0048468]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cell proliferation in external granule layer [GO:0021924]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; cerebellar granule cell precursor proliferation [GO:0021930]; commissural neuron axon guidance [GO:0071679]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; determination of left/right symmetry [GO:0007368]; developmental growth [GO:0048589]; digestive tract mesoderm development [GO:0007502]; digestive tract morphogenesis [GO:0048546]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic morphogenesis [GO:0048598]; embryonic organ development [GO:0048568]; embryonic skeletal system development [GO:0048706]; endocytosis [GO:0006897]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial-mesenchymal cell signaling [GO:0060684]; epithelial-mesenchymal signaling involved in prostate gland development [GO:0060738]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of cell polarity [GO:0030010]; forebrain development [GO:0030900]; forebrain regionalization [GO:0021871]; formation of anatomical boundary [GO:0048859]; fungiform papilla development [GO:0061196]; fungiform papilla formation [GO:0061198]; fungiform papilla morphogenesis [GO:0061197]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; inner ear development [GO:0048839]; intein-mediated protein splicing [GO:0016539]; intermediate filament organization [GO:0045109]; kidney development [GO:0001822]; left lung development [GO:0060459]; limb bud formation [GO:0060174]; limb development [GO:0060173]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung lobe morphogenesis [GO:0060463]; lung morphogenesis [GO:0060425]; lymphoid progenitor cell differentiation [GO:0002320]; male genitalia development [GO:0030539]; male genitalia morphogenesis [GO:0048808]; mesenchymal cell proliferation [GO:0010463]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal smoothened signaling pathway involved in prostate gland development [GO:0060783]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephros development [GO:0001656]; midbrain development [GO:0030901]; myoblast differentiation [GO:0045445]; myotube differentiation [GO:0014902]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of gene expression [GO:0010629]; negative regulation of kidney smooth muscle cell differentiation [GO:2000357]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of neuron death [GO:1901215]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of ureter smooth muscle cell differentiation [GO:2000062]; negative regulation of Wnt signaling pathway [GO:0030178]; negative thymic T cell selection [GO:0045060]; neural crest cell migration [GO:0001755]; neural tube formation [GO:0001841]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; odontogenesis [GO:0042476]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; osteoblast development [GO:0002076]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; polarity specification of anterior/posterior axis [GO:0009949]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cerebellar granule cell precursor proliferation [GO:0021940]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of gene expression [GO:0010628]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of kidney smooth muscle cell differentiation [GO:2000358]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mesenchymal cell proliferation involved in ureter development [GO:2000729]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neurotrophin production [GO:0032901]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; positive regulation of penile erection [GO:0060406]; positive regulation of photoreceptor cell differentiation [GO:0046534]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sclerotome development [GO:0061189]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ureter smooth muscle cell differentiation [GO:2000063]; positive regulation of Wnt signaling pathway [GO:0030177]; positive thymic T cell selection [GO:0045059]; primary prostatic bud elongation [GO:0060516]; prostate epithelial cord elongation [GO:0060523]; prostate gland development [GO:0030850]; protein localization to nucleus [GO:0034504]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of gene expression [GO:0010468]; regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782]; regulation of odontogenesis [GO:0042481]; regulation of prostatic bud formation [GO:0060685]; regulation of protein localization to nucleus [GO:1900180]; regulation of proteolysis [GO:0030162]; regulation of transcription, DNA-templated [GO:0006355]; respiratory tube development [GO:0030323]; response to axon injury [GO:0048678]; response to ethanol [GO:0045471]; right lung development [GO:0060458]; roof of mouth development [GO:0060021]; salivary gland cavitation [GO:0060662]; signal transduction [GO:0007165]; skin development [GO:0043588]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; somite development [GO:0061053]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord motor neuron differentiation [GO:0021522]; stem cell development [GO:0048864]; striated muscle cell differentiation [GO:0051146]; striated muscle tissue development [GO:0014706]; T cell differentiation in thymus [GO:0033077]; telencephalon regionalization [GO:0021978]; thalamus development [GO:0021794]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue development [GO:0043586]; tongue morphogenesis [GO:0043587]; trachea development [GO:0060438]; trachea morphogenesis [GO:0060439]; tracheoesophageal septum formation [GO:1905327]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; ventral spinal cord interneuron specification [GO:0021521]; zona limitans intrathalamica formation [GO:0022006]	anterior/posterior pattern specification [GO:0009952]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; cerebral cortex development [GO:0021987]; embryonic body morphogenesis [GO:0010172]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; lens development in camera-type eye [GO:0002088]; myoblast fusion [GO:0007520]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of protein binding [GO:0043393]; skeletal muscle satellite cell differentiation [GO:0014816]; smoothened signaling pathway [GO:0007224]	axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]; transport vesicle [GO:0030133]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; laminin-1 binding [GO:0043237]; patched binding [GO:0005113]; zinc ion binding [GO:0008270]	
d3d1qa__d1oesa___1		Metazoa	Firmicutes	Chordata	protein tyrosine phosphatase activity [GO:0004725]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]		actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]		cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3d1qb__d1fpze___1		Metazoa	Firmicutes	Chordata	protein tyrosine phosphatase activity [GO:0004725]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cell cycle arrest [GO:0007050]; cilium assembly [GO:0060271]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell population proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]		cell cycle arrest [GO:0007050]; cilium assembly [GO:0060271]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell population proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]	protein tyrosine phosphatase activity [GO:0004725]	protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d3d1xb__d5p6aa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3d1yb__d2jxra___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]; autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]
d3d1zb__d3vfba___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3d20a__d1xe5a___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3d21a__d5a4uf1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell [GO:0005623]; cytoplasm [GO:0005737]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	protein disulfide oxidoreductase activity [GO:0015035]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d3d21b__d2jl4b1__1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; maleylpyruvate isomerase activity [GO:0050077]; aromatic amino acid family metabolic process [GO:0009072]; aromatic compound catabolic process [GO:0019439]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	aromatic amino acid family metabolic process [GO:0009072]; aromatic compound catabolic process [GO:0019439]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	protein disulfide oxidoreductase activity [GO:0015035]	maleylpyruvate isomerase activity [GO:0050077]
d3d23b1_d1o2ha___1		Metazoa		Chordata	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3d23c__d5fx5a___1					host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3d25b__d3c60f1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d3d27a__d2bhba2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	cytosol [GO:0005829]; aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]	protein initiator methionine removal [GO:0070084]		cytosol [GO:0005829]	cytosol [GO:0005829]	ferrous iron binding [GO:0008198]; metalloaminopeptidase activity [GO:0070006]	aminopeptidase activity [GO:0004177]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]
d3d29e__d3gpjk___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3d29i__d4qlqz___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3d29k__d4qvpe___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3d2ca__d4lipe___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d3d2cc__d1r4zb___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d3d2cc__d5ah0a1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]		lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d3d2cf__d1ys2x___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d3d2ch__d1cqza2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cytosol [GO:0005829]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]	lipid catabolic process [GO:0016042]	cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]	extracellular region [GO:0005576]	cytosol [GO:0005829]; peroxisome [GO:0005777]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3d2cj__d1ji3b___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	metal ion binding [GO:0046872]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]		lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]
d3d2cl__d4hs9a___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]		lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d3d2fb2_d3bf3f2__1	Metazoa		Chordata	Thermotogae	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	coenzyme A biosynthetic process [GO:0015937]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d3d2ta__d2iglc1__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	periplasmic space [GO:0042597]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]
d3d2ud1_d1biha2__1	Metazoa	Metazoa	Chordata	Arthropoda	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; innate immune response [GO:0045087]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	innate immune response [GO:0045087]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3d39b1_d5iw1c2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3d3ba__d3imqc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; structural constituent of ribosome [GO:0003735]; transcription antitermination factor activity, RNA binding [GO:0001072]; tRNA binding [GO:0000049]; transcription antitermination [GO:0031564]; translation [GO:0006412]	cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; structural constituent of ribosome [GO:0003735]; transcription antitermination factor activity, RNA binding [GO:0001072]; tRNA binding [GO:0000049]; transcription antitermination [GO:0031564]; translation [GO:0006412]	transcription antitermination [GO:0031564]; translation [GO:0006412]	transcription antitermination [GO:0031564]; translation [GO:0006412]	cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]	cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]	structural constituent of ribosome [GO:0003735]; transcription antitermination factor activity, RNA binding [GO:0001072]; tRNA binding [GO:0000049]	structural constituent of ribosome [GO:0003735]; transcription antitermination factor activity, RNA binding [GO:0001072]; tRNA binding [GO:0000049]
d3d3ca__d1sqga1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; structural constituent of ribosome [GO:0003735]; transcription antitermination factor activity, RNA binding [GO:0001072]; tRNA binding [GO:0000049]; transcription antitermination [GO:0031564]; translation [GO:0006412]	cytosol [GO:0005829]; RNA binding [GO:0003723]; rRNA (cytosine-C5-)-methyltransferase activity [GO:0009383]; regulation of transcription, DNA-templated [GO:0006355]; rRNA base methylation [GO:0070475]	transcription antitermination [GO:0031564]; translation [GO:0006412]	regulation of transcription, DNA-templated [GO:0006355]; rRNA base methylation [GO:0070475]	cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]	cytosol [GO:0005829]	structural constituent of ribosome [GO:0003735]; transcription antitermination factor activity, RNA binding [GO:0001072]; tRNA binding [GO:0000049]	RNA binding [GO:0003723]; rRNA (cytosine-C5-)-methyltransferase activity [GO:0009383]
d3d3fa__d4ijcb___1		Fungi	Firmicutes	Ascomycota	methylglyoxal reductase (NADPH-dependent) activity [GO:0043892]	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; D-arabinose 1-dehydrogenase [NAD(P)+] activity [GO:0045290]; oxidoreductase activity [GO:0016491]; cellular carbohydrate metabolic process [GO:0044262]		cellular carbohydrate metabolic process [GO:0044262]		cytosol [GO:0005829]	methylglyoxal reductase (NADPH-dependent) activity [GO:0043892]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; D-arabinose 1-dehydrogenase [NAD(P)+] activity [GO:0045290]; oxidoreductase activity [GO:0016491]
d3d3pa__d4msaa1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3d3vb1_d1s78d2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]
d3d3vb1_d2xv6b1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3d4da__d1ey5a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3d4kb__d1cr7b___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3d4la1_d4lkob1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3d4la2_d5xg0a1__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; carboxylic ester hydrolase activity [GO:0052689]; cellular response to organic substance [GO:0071310]; xenobiotic catabolic process [GO:0042178]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellular response to organic substance [GO:0071310]; xenobiotic catabolic process [GO:0042178]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	carboxylic ester hydrolase activity [GO:0052689]
d3d4ma__d1gule2__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytosol [GO:0005829]	disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3d4vb2_d1qnea1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]	alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3d4vd1_d1rrqa1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	base-excision repair [GO:0006284]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]
d3d4vd2_d1pczb2__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]	DNA-templated transcription, initiation [GO:0006352]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3d4xc__d3s65d___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3d4za1_d3p0ba2__1	Metazoa		Arthropoda	Deinococcus-Thermus	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; alpha-glucan biosynthetic process [GO:0030979]; glycogen biosynthetic process [GO:0005978]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	alpha-glucan biosynthetic process [GO:0030979]; glycogen biosynthetic process [GO:0005978]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]
d3d4za3_d1k1yb3__1	Metazoa		Arthropoda	Euryarchaeota	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]
d3d51a1_d2b5dx1__1	Metazoa		Arthropoda		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	
d3d54a2_d5avmh2__1			Thermotogae	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; phosphoribosylformylglycinamidine cyclo-ligase activity [GO:0004641]
d3d54a4_d3c9sa2__1			Thermotogae	Aquificae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]
d3d54e2_d2z1ea1__1			Thermotogae	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d3d5ai1_d2c39n1__1				Crenarchaeota		cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]		rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]
d3d5aq1_d1eyga___1				Proteobacteria		cytosol [GO:0005829]; enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]		DNA replication [GO:0006260]; mismatch repair [GO:0006298]; positive regulation of catalytic activity [GO:0043085]; positive regulation of helicase activity [GO:0051096]; recombinational repair [GO:0000725]; SOS response [GO:0009432]		cytosol [GO:0005829]		enzyme activator activity [GO:0008047]; identical protein binding [GO:0042802]; single-stranded DNA binding [GO:0003697]
d3d5bo1_d2hgqn1__1												
d3d5ci1_d5elwa1__1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]; histidine biosynthetic process [GO:0000105]		histidine biosynthetic process [GO:0000105]		chloroplast [GO:0009507]		imidazoleglycerol-phosphate dehydratase activity [GO:0004424]; metal ion binding [GO:0046872]
d3d5do1_d1vq9k1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d3d5du1_d2aw4q1__1												
d3d5ha__d3apgc1__1	Viridiplantae		Streptophyta	Euryarchaeota	alpha-amylase inhibitor activity [GO:0015066]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			alpha-amylase inhibitor activity [GO:0015066]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3d5ja1_d5aixd1__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d3d5oa__d2eaka___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]
d3d5ob__d1bzwc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3d5oc__d3pvop___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d3d5oc__d5ik5a2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	signaling receptor binding [GO:0005102]
d3d5od__d1gnha___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d3d5oe__d1fyua___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]
d3d5ra2_d5im1a1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d3d5tb2_d3gvhb2__1			Proteobacteria	Proteobacteria	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]			L-malate dehydrogenase activity [GO:0030060]	L-malate dehydrogenase activity [GO:0030060]
d3d5tc1_d1u3ub2__1		Metazoa	Proteobacteria	Chordata	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	L-malate dehydrogenase activity [GO:0030060]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d3d5tc2_d2v7pc2__1			Proteobacteria	Deinococcus-Thermus	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]
d3d5tc2_d4qo7a2__1		Metazoa	Proteobacteria	Chordata	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-malate dehydrogenase activity [GO:0030060]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d3d5za__d1y7bc2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	arabinan catabolic process [GO:0031222]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3d60a__d1y4wa2__1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	extracellular region [GO:0005576]; fructan beta-fructosidase activity [GO:0051669]; polysaccharide catabolic process [GO:0000272]	arabinan catabolic process [GO:0031222]	polysaccharide catabolic process [GO:0000272]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]	fructan beta-fructosidase activity [GO:0051669]
d3d60a__d2exka2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	arabinan catabolic process [GO:0031222]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3d63a__d1mjxa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; membrane [GO:0016020]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]
d3d63b__d3sw5f___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3d63c1_d1i40a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; membrane [GO:0016020]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]
d3d6ga1_d1q9ob1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3d6gb2_d2p7tb1__1	Metazoa		Chordata	Actinobacteria	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	voltage-gated potassium channel complex [GO:0008076]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d3d6pa__d4qfib___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; angiogenesis [GO:0001525]; diacylglycerol biosynthetic process [GO:0006651]; liver development [GO:0001889]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein secretion [GO:0050714]; response to hypoxia [GO:0001666]; rRNA transcription [GO:0009303]		actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; angiogenesis [GO:0001525]; diacylglycerol biosynthetic process [GO:0006651]; liver development [GO:0001889]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein secretion [GO:0050714]; response to hypoxia [GO:0001666]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]	angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleus [GO:0005634]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; signaling receptor binding [GO:0005102]
d3d6ya2_d3r8ka___1		Metazoa	Firmicutes	Chordata	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; negative regulation of mitochondrial membrane potential [GO:0010917]; neutrophil degranulation [GO:0043312]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940]	regulation of transcription, DNA-templated [GO:0006355]	negative regulation of mitochondrial membrane potential [GO:0010917]; neutrophil degranulation [GO:0043312]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	DNA binding [GO:0003677]	heme binding [GO:0020037]
d3d70a1_d1q08b___1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; zinc ion binding [GO:0008270]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	regulation of transcription, DNA-templated [GO:0006355]	positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]			DNA binding [GO:0003677]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; zinc ion binding [GO:0008270]
d3d70a1_d5gped___1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; positive regulation of transcription, DNA-templated [GO:0045893]	regulation of transcription, DNA-templated [GO:0006355]	positive regulation of transcription, DNA-templated [GO:0045893]			DNA binding [GO:0003677]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]
d3d70a2_d1exia2__1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d3d71a1_d1q0ab___1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; zinc ion binding [GO:0008270]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	regulation of transcription, DNA-templated [GO:0006355]	positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]			DNA binding [GO:0003677]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; zinc ion binding [GO:0008270]
d3d71a2_d1r8ea2__1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d3d71a2_d5gqqa___1		Metazoa	Firmicutes	Chordata	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; negative regulation of mitochondrial membrane potential [GO:0010917]; neutrophil degranulation [GO:0043312]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940]	regulation of transcription, DNA-templated [GO:0006355]	negative regulation of mitochondrial membrane potential [GO:0010917]; neutrophil degranulation [GO:0043312]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	DNA binding [GO:0003677]	heme binding [GO:0020037]
d3d73a__d2wcla___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]		response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]			odorant binding [GO:0005549]	odorant binding [GO:0005549]
d3d73b__d3r72a___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d3d76a__d3k1eb___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d3d77a__d3k1ea___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d3d78b__d3v2la1__1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]		olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]	odorant binding [GO:0005549]	dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]
d3d7ab__d1iq4a___1			Euryarchaeota	Firmicutes		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d3d7ba__d4ahia___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]
d3d7bb__d1hi2a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; chemotaxis [GO:0006935]; defense response to virus [GO:0051607]; neutrophil degranulation [GO:0043312]; RNA catabolic process [GO:0006401]; RNA phosphodiester bond hydrolysis [GO:0090501]		chemotaxis [GO:0006935]; defense response to virus [GO:0051607]; neutrophil degranulation [GO:0043312]; RNA catabolic process [GO:0006401]; RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular region [GO:0005576]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d3d7eo2_d2nzta4__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; plasma membrane [GO:0005886]; sarcoplasmic reticulum [GO:0016529]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; apoptotic mitochondrial changes [GO:0008637]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to leukemia inhibitory factor [GO:1990830]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; lactation [GO:0007595]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of mitochondrial membrane permeability [GO:0035795]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; regulation of glucose import [GO:0046324]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	apoptotic mitochondrial changes [GO:0008637]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to leukemia inhibitory factor [GO:1990830]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; lactation [GO:0007595]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of mitochondrial membrane permeability [GO:0035795]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; regulation of glucose import [GO:0046324]; response to hypoxia [GO:0001666]; response to ischemia [GO:0002931]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; plasma membrane [GO:0005886]; sarcoplasmic reticulum [GO:0016529]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]
d3d7oa__d2zs1a___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3d7sd1_d2ywwb1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	aspartate carbamoyltransferase complex [GO:0009347]; metal ion binding [GO:0046872]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	aspartate carbamoyltransferase complex [GO:0009347]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	metal ion binding [GO:0046872]
d3d84x__d3sa2a1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d3d85a1_d4p5kd2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d3d87d1_d1j88c1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]; cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]	Fc-epsilon receptor signaling pathway [GO:0038095]	cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	IgE binding [GO:0019863]
d3d8va1_d1jn8d___1			Actinobacteria		cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]; adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]	
d3d95a__d3fela___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3d95a__d4zhhf___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d3d96a__d1g74a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d3d96a__d3fw4a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d3d96b__d2a0aa1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	lipid binding [GO:0008289]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	lipid binding [GO:0008289]
d3d96b__d5khpb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d3d97a__d1dzja___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	small molecule binding [GO:0036094]
d3d97b__d3u03c___1	Metazoa		Chordata		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	
d3d98a2_d3i3ab___1			Actinobacteria	Spirochaetes	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]; adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]
d3d98a2_d4ac3a2__1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]; adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d3d9ac__d1ip7a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3d9da2_d5ahsc2__1	Fungi		Ascomycota	Proteobacteria	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]				FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d3d9dd2_d5k3ja3__1	Fungi	Metazoa	Ascomycota	Nematoda (roundworms)	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]		peroxisome [GO:0005777]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]
d3d9ec2_d5ahsa2__1	Fungi		Ascomycota	Proteobacteria	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]				FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d3d9ed2_d2dvla2__1	Fungi		Ascomycota	Deinococcus-Thermus	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]				FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d3d9fa2_d3mddb1__1	Fungi	Metazoa	Ascomycota	Chordata	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]
d3d9ga2_d1u8vc1__1	Fungi		Ascomycota	Firmicutes	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybutanoyl-CoA dehydratase activity [GO:0043721]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; vinylacetyl-CoA delta-isomerase activity [GO:0050393]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]				FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	4-hydroxybutanoyl-CoA dehydratase activity [GO:0043721]; 4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; vinylacetyl-CoA delta-isomerase activity [GO:0050393]
d3d9gb2_d5k3ih2__1	Fungi	Metazoa	Ascomycota	Nematoda (roundworms)	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]		peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]
d3d9ja1_d1ujjb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mRNA cleavage factor complex [GO:0005849]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA polymerase core enzyme binding [GO:0043175]; RNA polymerase II C-terminal domain phosphoserine binding [GO:1990269]; RNA polymerase II complex binding [GO:0000993]; mRNA polyadenylation [GO:0006378]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; termination of RNA polymerase II transcription [GO:0006369]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	mRNA polyadenylation [GO:0006378]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; termination of RNA polymerase II transcription [GO:0006369]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; mRNA cleavage factor complex [GO:0005849]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA polymerase core enzyme binding [GO:0043175]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II C-terminal domain phosphoserine binding [GO:1990269]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3d9ja1_d4fldb___1	Metazoa		Chordata		cytoplasm [GO:0005737]; mRNA cleavage factor complex [GO:0005849]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA polymerase core enzyme binding [GO:0043175]; RNA polymerase II C-terminal domain phosphoserine binding [GO:1990269]; RNA polymerase II complex binding [GO:0000993]; mRNA polyadenylation [GO:0006378]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; termination of RNA polymerase II transcription [GO:0006369]		mRNA polyadenylation [GO:0006378]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; termination of RNA polymerase II transcription [GO:0006369]		cytoplasm [GO:0005737]; mRNA cleavage factor complex [GO:0005849]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA polymerase core enzyme binding [GO:0043175]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II C-terminal domain phosphoserine binding [GO:1990269]	
d3d9jb1_d1jwgb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mRNA cleavage factor complex [GO:0005849]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA polymerase core enzyme binding [GO:0043175]; RNA polymerase II C-terminal domain phosphoserine binding [GO:1990269]; RNA polymerase II complex binding [GO:0000993]; mRNA polyadenylation [GO:0006378]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; termination of RNA polymerase II transcription [GO:0006369]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	mRNA polyadenylation [GO:0006378]; negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000805]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; termination of RNA polymerase II transcription [GO:0006369]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	cytoplasm [GO:0005737]; mRNA cleavage factor complex [GO:0005849]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]; RNA polymerase core enzyme binding [GO:0043175]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II C-terminal domain phosphoserine binding [GO:1990269]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]
d3d9qx__d1au9a___1	Fungi		Ascomycota	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3d9wd__d1yt7a___1		Metazoa	Actinobacteria	Chordata	acetyltransferase activity [GO:0016407]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]		autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]		endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	acetyltransferase activity [GO:0016407]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d3d9yb__d5fegb___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	actin cortical patch [GO:0030479]; cell [GO:0005623]; cell cortex [GO:0005938]; cell cortex of cell tip [GO:0051285]; mating projection tip [GO:0043332]; medial cortex [GO:0031097]; actin monomer binding [GO:0003785]; guanyl-nucleotide exchange factor activity [GO:0005085]; actin cortical patch organization [GO:0044396]; actin filament polymerization [GO:0030041]; cytogamy [GO:0000755]; mitotic actomyosin contractile ring assembly [GO:1903475]; negative regulation of actin filament binding [GO:1904530]; negative regulation of actin filament polymerization [GO:0030837]; regulation of barbed-end actin filament capping [GO:2000812]; sequestering of actin monomers [GO:0042989]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin binding [GO:0003779]; protein self-association [GO:0043621]	actin cortical patch organization [GO:0044396]; actin filament polymerization [GO:0030041]; cytogamy [GO:0000755]; mitotic actomyosin contractile ring assembly [GO:1903475]; negative regulation of actin filament binding [GO:1904530]; negative regulation of actin filament polymerization [GO:0030837]; regulation of barbed-end actin filament capping [GO:2000812]; sequestering of actin monomers [GO:0042989]		actin cortical patch [GO:0030479]; cell [GO:0005623]; cell cortex [GO:0005938]; cell cortex of cell tip [GO:0051285]; mating projection tip [GO:0043332]; medial cortex [GO:0031097]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin monomer binding [GO:0003785]; guanyl-nucleotide exchange factor activity [GO:0005085]	actin binding [GO:0003779]; protein self-association [GO:0043621]
d3da0a2_d3hg0c2__1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]	virus tail, baseplate [GO:0098025]		
d3daha1_d4jitb___1			Proteobacteria		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]		5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]	
d3daqc__d2v8zb___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; 2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]; aldonic acid catabolic process [GO:0046176]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aldonic acid catabolic process [GO:0046176]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]
d3daqd__d1wbha1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; membrane [GO:0016020]; (4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]; metabolic process [GO:0008152]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	metabolic process [GO:0008152]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	(4S)-4-hydroxy-2-oxoglutarate aldolase activity [GO:0106009]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; 2-keto-3-deoxygluconate aldolase activity [GO:0043725]; 4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]; identical protein binding [GO:0042802]; oxaloacetate decarboxylase activity [GO:0008948]; oxo-acid-lyase activity [GO:0016833]
d3dara__d5vr9l2__1	Metazoa		Chordata		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]		angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]		cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	
d3data__d3l3ra___1		Metazoa	Firmicutes	Chordata	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3dawa1_d2wusa2__1	Metazoa		Chordata	Thermotogae	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	integral component of membrane [GO:0016021]; DNA binding [GO:0003677]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	integral component of membrane [GO:0016021]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	DNA binding [GO:0003677]
d3dawa1_d3r9pb2__1	Metazoa		Chordata	Actinobacteria	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cytoplasm [GO:0005737]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]
d3dbhk__d4p7ia1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]; cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d3dbhk__d5o44f___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]; cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3dbhl__d4hjka1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]; cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]	protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d3dbjg__d5chrb___1		Metazoa	Cyanobacteria	Annelida	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d3dbrj1_d1xqqa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]; cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d3dbvq2_d1ff9a2__1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity [GO:0004755]
d3dbvr2_d3qvta2__1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	integral component of membrane [GO:0016021]; inositol-3-phosphate synthase activity [GO:0004512]; nucleotide binding [GO:0000166]; inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	inositol-3-phosphate synthase activity [GO:0004512]; nucleotide binding [GO:0000166]
d3dbxa2_d2i9la1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3dc2b2_d4fcca2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; plasma membrane [GO:0005886]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; cellular amino acid metabolic process [GO:0006520]; L-serine biosynthetic process [GO:0006564]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]; L-serine biosynthetic process [GO:0006564]	cellular amino acid metabolic process [GO:0006520]	cell wall [GO:0005618]; plasma membrane [GO:0005886]		NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d3dc3a__d1flja___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cytosol [GO:0005829]; carbonate dehydratase activity [GO:0004089]; nickel cation binding [GO:0016151]; phosphatase activity [GO:0016791]; zinc ion binding [GO:0008270]; response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; response to oxidative stress [GO:0006979]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	response to bacterium [GO:0009617]; response to ethanol [GO:0045471]; response to oxidative stress [GO:0006979]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; nickel cation binding [GO:0016151]; phosphatase activity [GO:0016791]; zinc ion binding [GO:0008270]
d3dc5c1_d1coja1__1	Metazoa		Nematoda (roundworms)	Aquificae	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	removal of superoxide radicals [GO:0019430]		mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]		manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3dc5c2_d1gn6c2__1	Metazoa		Nematoda (roundworms)	Actinobacteria	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	removal of superoxide radicals [GO:0019430]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3dc5c2_d4yetb2__1	Metazoa		Nematoda (roundworms)	Apicomplexa	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	removal of superoxide radicals [GO:0019430]		mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]		manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3dc6a1_d3evkd1__1	Metazoa		Nematoda (roundworms)	Crenarchaeota	mitochondrial matrix [GO:0005759]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	removal of superoxide radicals [GO:0019430]		mitochondrial matrix [GO:0005759]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]		manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3dc6a2_d5vf9a2__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	mitochondrial matrix [GO:0005759]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	removal of superoxide radicals [GO:0019430]	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0003069]; age-dependent response to reactive oxygen species [GO:0001315]; cellular response to oxidative stress [GO:0034599]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; oxygen homeostasis [GO:0032364]; positive regulation of cell migration [GO:0030335]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching [GO:1905932]; protein homotetramerization [GO:0051289]; regulation of blood pressure [GO:0008217]; regulation of transcription by RNA polymerase II [GO:0006357]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrial matrix [GO:0005759]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3dc6c1_d1rfwa1__1	Metazoa		Nematoda (roundworms)		mitochondrial matrix [GO:0005759]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]		mitochondrial matrix [GO:0005759]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]		manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]	
d3dc6c2_d2nyba2__1	Metazoa		Nematoda (roundworms)	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	removal of superoxide radicals [GO:0019430]	oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]	mitochondrial matrix [GO:0005759]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]
d3dcca__d3p58a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3dcca__d4xfwb___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3dcqc__d2vnve___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3dd3a1_d3dwva___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glycosome [GO:0020015]; glutathione peroxidase activity [GO:0004602]; response to oxidative stress [GO:0006979]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glycosome [GO:0020015]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]
d3dd5b__d5gv5a___1	Fungi	Fungi	Ascomycota	Basidiomycota	extracellular region [GO:0005576]; cutinase activity [GO:0050525]; pathogenesis [GO:0009405]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	pathogenesis [GO:0009405]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]		cutinase activity [GO:0050525]	triglyceride lipase activity [GO:0004806]
d3dd5c__d1yb7a___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; cutinase activity [GO:0050525]; pathogenesis [GO:0009405]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]		cutinase activity [GO:0050525]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]
d3dd5e__d2ajba2__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; cutinase activity [GO:0050525]; pathogenesis [GO:0009405]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	cutinase activity [GO:0050525]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3dd5g__d3m81e___1	Fungi		Ascomycota	Thermotogae	extracellular region [GO:0005576]; cutinase activity [GO:0050525]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]	pathogenesis [GO:0009405]	cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	cutinase activity [GO:0050525]	acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]
d3ddfa2_d3vdbd5__1	Metazoa		Arthropoda	Proteobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	beta-galactosidase complex [GO:0009341]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3ddpb2_d1c9bq1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3ddqb2_d2phga2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3ddqd2_d3f5xb1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d3ddvb__d1g1ba___1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cytosol [GO:0005829]; chorismate lyase activity [GO:0008813]; pyruvate biosynthetic process [GO:0042866]; ubiquinone biosynthetic process [GO:0006744]		pyruvate biosynthetic process [GO:0042866]; ubiquinone biosynthetic process [GO:0006744]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	chorismate lyase activity [GO:0008813]
d3ddvd__d2nwie2__1			Firmicutes	Euryarchaeota	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]						DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	
d3de6x__d1y34e2__1	Fungi		Ascomycota	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3de8b__d1a7vb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3de8b__d3iq6f___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3de8c__d5l32b___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3de8d__d5jlia___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3de8d__d5l32d___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3de9a__d5jp7a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3deba1_d1xuda___1		Metazoa		Chordata	extracellular region [GO:0005576]; ganglioside binding [GO:0035594]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; membrane protein proteolysis [GO:0033619]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	membrane protein proteolysis [GO:0033619]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of neurotransmitter secretion [GO:0046929]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	ganglioside binding [GO:0035594]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d3delb1_d4ys9b___1			Chlamydiae	Proteobacteria	cell surface [GO:0009986]; extracellular region [GO:0005576]; amino acid transport [GO:0006865]	periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]	amino acid transport [GO:0006865]		cell surface [GO:0009986]; extracellular region [GO:0005576]	periplasmic space [GO:0042597]		carbohydrate transmembrane transporter activity [GO:0015144]
d3delc1_d4nq8b1__1			Chlamydiae	Proteobacteria	cell surface [GO:0009986]; extracellular region [GO:0005576]; amino acid transport [GO:0006865]	outer membrane-bounded periplasmic space [GO:0030288]; transmembrane transport [GO:0055085]	amino acid transport [GO:0006865]	transmembrane transport [GO:0055085]	cell surface [GO:0009986]; extracellular region [GO:0005576]	outer membrane-bounded periplasmic space [GO:0030288]		
d3dema1_d5ckma3__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; peptidase activity [GO:0008233]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; negative regulation of complement activation [GO:0045916]; receptor-mediated endocytosis [GO:0006898]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; negative regulation of complement activation [GO:0045916]; receptor-mediated endocytosis [GO:0006898]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]	extracellular space [GO:0005615]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; peptidase activity [GO:0008233]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]
d3deoa2_d3so8a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; signal recognition particle, chloroplast targeting [GO:0080085]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; protein domain specific binding [GO:0019904]; protein heterotrimerization [GO:0070208]; protein import into chloroplast thylakoid membrane [GO:0045038]; response to high light intensity [GO:0009644]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; histone deacetylase binding [GO:0042826]; low-density lipoprotein particle receptor binding [GO:0050750]; protein kinase binding [GO:0019901]; ubiquitin protein ligase binding [GO:0031625]; regulation of protein complex assembly [GO:0043254]	protein heterotrimerization [GO:0070208]; protein import into chloroplast thylakoid membrane [GO:0045038]; response to high light intensity [GO:0009644]	regulation of protein complex assembly [GO:0043254]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; signal recognition particle, chloroplast targeting [GO:0080085]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; protein domain specific binding [GO:0019904]	histone deacetylase binding [GO:0042826]; low-density lipoprotein particle receptor binding [GO:0050750]; protein kinase binding [GO:0019901]; ubiquitin protein ligase binding [GO:0031625]
d3depa2_d3twva___1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; signal recognition particle, chloroplast targeting [GO:0080085]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; protein domain specific binding [GO:0019904]; protein heterotrimerization [GO:0070208]; protein import into chloroplast thylakoid membrane [GO:0045038]; response to high light intensity [GO:0009644]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	protein heterotrimerization [GO:0070208]; protein import into chloroplast thylakoid membrane [GO:0045038]; response to high light intensity [GO:0009644]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; signal recognition particle, chloroplast targeting [GO:0080085]; signal recognition particle, endoplasmic reticulum targeting [GO:0005786]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; protein domain specific binding [GO:0019904]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]
d3deqa2_d1w6tb1__1			Thermotogae	Firmicutes	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	glycolytic process [GO:0006096]; pathogenesis [GO:0009405]		cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3deqd1_d2akma2__1		Metazoa	Thermotogae	Chordata	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3deqd2_d3twab2__1			Thermotogae	Proteobacteria	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]
d3desa1_d6enla2__1		Fungi	Thermotogae	Ascomycota	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3desa2_d2xh0c2__1		Fungi	Thermotogae	Ascomycota	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3desb2_d3t6cb2__1			Thermotogae	Proteobacteria	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]
d3detd1_d2ny5c2__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3detd2_d3nn8b___1			Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	
d3detf1_d3ck0l2__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3detf2_d1t0mb___1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3detf2_d5b3jl1__1		Metazoa	Proteobacteria	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; NMDA selective glutamate receptor complex [GO:0017146]; postsynaptic membrane [GO:0045211]; metal ion binding [GO:0046872]; NMDA glutamate receptor activity [GO:0004972]; protein heterotetramerization [GO:0051290]; response to zinc ion [GO:0010043]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	protein heterotetramerization [GO:0051290]; response to zinc ion [GO:0010043]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; NMDA selective glutamate receptor complex [GO:0017146]; postsynaptic membrane [GO:0045211]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]	metal ion binding [GO:0046872]; NMDA glutamate receptor activity [GO:0004972]
d3dexc__d2hsya___1		Fungi	Actinobacteria	Ascomycota		cell [GO:0005623]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; glutathione metabolic process [GO:0006749]; glycerol ether metabolic process [GO:0006662]; protein deglutathionylation [GO:0080058]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; sulfate assimilation [GO:0000103]; vacuole fusion, non-autophagic [GO:0042144]; vacuole inheritance [GO:0000011]		cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; glutathione metabolic process [GO:0006749]; glycerol ether metabolic process [GO:0006662]; protein deglutathionylation [GO:0080058]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; sulfate assimilation [GO:0000103]; vacuole fusion, non-autophagic [GO:0042144]; vacuole inheritance [GO:0000011]		cell [GO:0005623]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]		disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]
d3dexe__d1k0bb2__1		Fungi	Actinobacteria	Ascomycota		cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]; cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasmic sequestering of transcription factor [GO:0042994]; nitrate assimilation [GO:0042128]; protein urmylation [GO:0032447]; regulation of nitrogen utilization [GO:0006808]; response to aluminum ion [GO:0010044]		cytoplasm [GO:0005737]		glutathione peroxidase activity [GO:0004602]; phosphoprotein binding [GO:0051219]; transcription corepressor activity [GO:0003714]
d3dexg__d1trua___1		Metazoa	Actinobacteria	Chordata		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]		activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d3dexg__d2khpa1__1			Actinobacteria	Proteobacteria		cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]; cytoplasm [GO:0005737]		electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d3df1c2_d2j02c2__1												
d3df1f1_d1xmqf___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d3df1m1_d1i96m___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d3df231_d3dll31__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d3df2c1_d2hgqd1__1												
d3df2i2_d3cjsb1__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; protein methyltransferase activity [GO:0008276]				cytoplasm [GO:0005737]		protein methyltransferase activity [GO:0008276]
d3df2l1_d2vhnl1__1												
d3df2t1_d2j03x1__1												
d3df3l1_d1ph2a3__1				Ciliophora		nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]		telomere capping [GO:0016233]		nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]		protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d3df3s1_d2b64s1__1												
d3df3t1_d2uxdt1__1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d3df4d1_d4m2la2__1				Crenarchaeota		cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d3df9b__d4ttaa___1			Proteobacteria	Proteobacteria	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]		cytosol [GO:0005829]; membrane [GO:0016020]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]
d3dfha1_d1iyxb2__1			Proteobacteria	Firmicutes	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	cellular amino acid catabolic process [GO:0009063]	glycolytic process [GO:0006096]		cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3dfja1_d4jnlu___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; sodium channel regulator activity [GO:0017080]; cornification [GO:0070268]; positive regulation of sodium ion transport [GO:0010765]		cornification [GO:0070268]; positive regulation of sodium ion transport [GO:0010765]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; sodium channel regulator activity [GO:0017080]	
d3dfod__d2nx3c___1	Metazoa		Chordata	Aquificae	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	I band [GO:0031674]; M band [GO:0031430]	cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]
d3dftd__d5hwma1__1	Metazoa		Chordata	Proteobacteria	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	5-dehydro-4-deoxyglucarate dehydratase activity [GO:0047448]; D-glucarate catabolic process [GO:0042838]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	D-glucarate catabolic process [GO:0042838]	I band [GO:0031674]; M band [GO:0031430]		fructose-bisphosphate aldolase activity [GO:0004332]	5-dehydro-4-deoxyglucarate dehydratase activity [GO:0047448]
d3dfya1_d5eu9c1__1		Metazoa	Thermotogae	Chordata	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3dfyn2_d1jpdx1__1			Thermotogae	Proteobacteria	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall organization [GO:0071555]; cellular amino acid catabolic process [GO:0009063]; peptidoglycan turnover [GO:0009254]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	cellular amino acid catabolic process [GO:0009063]; cell wall organization [GO:0071555]; peptidoglycan turnover [GO:0009254]			metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d3dfyo2_d4fp1a2__1			Thermotogae	Proteobacteria	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]			metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d3dfyp2_d2pcec2__1			Thermotogae	Proteobacteria	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	metal ion binding [GO:0046872]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]				metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	metal ion binding [GO:0046872]
d3dg3a2_d3qn3b2__1			Actinobacteria	Proteobacteria	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3dg6a2_d2dw6a1__1			Actinobacteria	Proteobacteria	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]		protein homooligomerization [GO:0051260]			isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]
d3dg7b2_d2o56a2__1			Actinobacteria	Proteobacteria	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3dg7b2_d4hcla2__1			Actinobacteria	Proteobacteria	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]					isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3dg7d2_d1tkkg1__1			Actinobacteria	Firmicutes	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]		cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]			isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d3dg8d__d5j7wd___1			Apicomplexa	Firmicutes	dihydrofolate reductase activity [GO:0004146]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]		cytoplasm [GO:0005737]	dihydrofolate reductase activity [GO:0004146]; thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d3dgad__d3nrra2__1			Apicomplexa	Apicomplexa	dihydrofolate reductase activity [GO:0004146]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; thymidylate synthase activity [GO:0004799]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]
d3dgeb1_d5b1oa1__1			Thermotogae	Proteobacteria	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; protein autophosphorylation [GO:0046777]	cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; regulation of response to osmotic stress [GO:0047484]; signal transduction by protein phosphorylation [GO:0023014]	protein autophosphorylation [GO:0046777]	phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; regulation of response to osmotic stress [GO:0047484]; signal transduction by protein phosphorylation [GO:0023014]	integral component of plasma membrane [GO:0005887]	cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]
d3dged__d2fspa___1			Thermotogae	Firmicutes	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; protein autophosphorylation [GO:0046777]	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	protein autophosphorylation [GO:0046777]	phosphorelay signal transduction system [GO:0000160]; sporulation resulting in formation of a cellular spore [GO:0030435]	integral component of plasma membrane [GO:0005887]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	kinase activity [GO:0016301]; metal ion binding [GO:0046872]
d3dged__d4d6xc___1			Thermotogae	Proteobacteria	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; protein autophosphorylation [GO:0046777]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	protein autophosphorylation [GO:0046777]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]		ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d3dgfc__d1zn2a2__1			Thermotogae	Proteobacteria	metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]			metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3dgga1_d1lo4l1__1		Metazoa		Chordata								
d3dgga2_d2wqra3__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3dggc2_d3o2dl2__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3dgqa2_d4yqmb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d3dgqb2_d5o00a2__1	Metazoa	Fungi	Chordata	Basidiomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	transferase activity [GO:0016740]
d3dgsa2_d3dgsb2__1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; pathogenesis [GO:0009405]; viral entry into host cell via pilus basal pore [GO:0039668]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; pathogenesis [GO:0009405]; viral entry into host cell via pilus basal pore [GO:0039668]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; pathogenesis [GO:0009405]; viral entry into host cell via pilus basal pore [GO:0039668]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; pathogenesis [GO:0009405]; viral entry into host cell via pilus basal pore [GO:0039668]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]		
d3dh1a1_d3mpzc1__1	Metazoa		Chordata	Actinobacteria	nucleoplasm [GO:0005654]; tRNA-specific adenosine-34 deaminase complex [GO:0052718]; tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA modification [GO:0006400]; tRNA wobble adenosine to inosine editing [GO:0002100]	cytidine deaminase activity [GO:0004126]; metal ion binding [GO:0046872]	tRNA modification [GO:0006400]; tRNA wobble adenosine to inosine editing [GO:0002100]		nucleoplasm [GO:0005654]; tRNA-specific adenosine-34 deaminase complex [GO:0052718]		tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; metal ion binding [GO:0046872]
d3dh1a1_d4ld2b___1	Metazoa		Chordata	Proteobacteria	nucleoplasm [GO:0005654]; tRNA-specific adenosine-34 deaminase complex [GO:0052718]; tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA modification [GO:0006400]; tRNA wobble adenosine to inosine editing [GO:0002100]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]	tRNA modification [GO:0006400]; tRNA wobble adenosine to inosine editing [GO:0002100]		nucleoplasm [GO:0005654]; tRNA-specific adenosine-34 deaminase complex [GO:0052718]		tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]
d3dh1b1_d1wwra1__1	Metazoa		Chordata	Aquificae	nucleoplasm [GO:0005654]; tRNA-specific adenosine-34 deaminase complex [GO:0052718]; tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA modification [GO:0006400]; tRNA wobble adenosine to inosine editing [GO:0002100]	tRNA-specific adenosine-34 deaminase complex [GO:0052718]; tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	tRNA modification [GO:0006400]; tRNA wobble adenosine to inosine editing [GO:0002100]	tRNA wobble adenosine to inosine editing [GO:0002100]	nucleoplasm [GO:0005654]; tRNA-specific adenosine-34 deaminase complex [GO:0052718]	tRNA-specific adenosine-34 deaminase complex [GO:0052718]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]
d3dh2b__d1gova___1			Actinobacteria	Firmicutes	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]				extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d3dh2c__d1rgea___1			Actinobacteria	Actinobacteria	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]				extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d3dh5a__d1oj1a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]		endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]
d3dh6a__d1z7xx___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular exosome [GO:0070062]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]		RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular region [GO:0005576]	extracellular exosome [GO:0070062]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]
d3dhgc__d3rncc___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d3dhgd__d1oq4a___1		Viridiplantae	Proteobacteria	Streptophyta	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	toluene catabolic process [GO:0042203]	fatty acid biosynthetic process [GO:0006633]		chloroplast [GO:0009507]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d3dhia__d3a68g___1		Viridiplantae	Proteobacteria	Streptophyta	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	toluene catabolic process [GO:0042203]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3dhma__d5b71c1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d3dhoa__d3spta2__1			Firmicutes	Actinobacteria	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]; adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	response to antibiotic [GO:0046677]	adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups [GO:0016746]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]
d3dhoa__d4myoc___1			Firmicutes	Firmicutes	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]			transferase activity, transferring acyl groups [GO:0016746]	transferase activity, transferring acyl groups [GO:0016746]
d3dhof__d3vnpc1__1			Firmicutes	Firmicutes	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]	response to antibiotic [GO:0046677]				transferase activity, transferring acyl groups [GO:0016746]	metal ion binding [GO:0046872]
d3dhrb__d1xzub___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3dhrc__d1yoia___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3dhrc__d2uulp___1	Metazoa		Chordata		hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3dhrd__d1aj9a___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3dhrg__d1jebc___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; myelin sheath [GO:0043209]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; erythrocyte development [GO:0048821]; hemopoiesis [GO:0030097]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; regulation of eIF2 alpha phosphorylation by heme [GO:0010999]		cellular oxidant detoxification [GO:0098869]; erythrocyte development [GO:0048821]; hemopoiesis [GO:0030097]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; regulation of eIF2 alpha phosphorylation by heme [GO:0010999]	hemoglobin complex [GO:0005833]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; myelin sheath [GO:0043209]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3dhwd1_d1b0ua1__1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; Gram-negative-bacterium-type cell wall [GO:0009276]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATPase-coupled transmembrane transporter activity [GO:0042626]; D-methionine transmembrane transporter activity [GO:0048474]; L-methionine transmembrane transporter activity [GO:0015191]; D-methionine transport [GO:0048473]	plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]	D-methionine transport [GO:0048473]		ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; Gram-negative-bacterium-type cell wall [GO:0009276]	plasma membrane [GO:0005886]	ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; D-methionine transmembrane transporter activity [GO:0048474]; L-methionine transmembrane transporter activity [GO:0015191]	ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATP binding [GO:0005524]
d3dhwg1_d2jj1l2__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; Gram-negative-bacterium-type cell wall [GO:0009276]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATPase-coupled transmembrane transporter activity [GO:0042626]; D-methionine transmembrane transporter activity [GO:0048474]; L-methionine transmembrane transporter activity [GO:0015191]; D-methionine transport [GO:0048473]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	D-methionine transport [GO:0048473]	ATP synthesis coupled proton transport [GO:0015986]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; Gram-negative-bacterium-type cell wall [GO:0009276]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]; D-methionine transmembrane transporter activity [GO:0048474]; L-methionine transmembrane transporter activity [GO:0015191]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3di0a__d1zajb___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]	I band [GO:0031674]; M band [GO:0031430]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	fructose-bisphosphate aldolase activity [GO:0004332]
d3di0b__d1ex5b___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]	I band [GO:0031674]; M band [GO:0031430]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	fructose-bisphosphate aldolase activity [GO:0004332]
d3di1b__d2nxii___1			Firmicutes	Aquificae	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]
d3di9a__d2e0ob1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular exosome [GO:0070062]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]		RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular region [GO:0005576]	extracellular exosome [GO:0070062]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease A activity [GO:0004522]; ribonuclease activity [GO:0004540]
d3diba__d1wbua___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d3dica__d5epza___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]
d3diea1_d3tjbc___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	protein disulfide oxidoreductase activity [GO:0015035]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d3dieb1_d1skwb___1			Firmicutes	Proteobacteria	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d3dieb1_d4o32c1__1			Firmicutes	Apicomplexa	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; PTEX complex [GO:0097619]; symbiont-containing vacuole [GO:0020003]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; PTEX complex [GO:0097619]; symbiont-containing vacuole [GO:0020003]	protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d3difa2_d4krmj___1		Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d3difc1_d1c16h___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3difc2_d5ip4b1__1		Metazoa		Chordata		axoneme [GO:0005930]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; neuron projection [GO:0043005]; microtubule binding [GO:0008017]; protein kinase binding [GO:0019901]; axoneme assembly [GO:0035082]; central nervous system development [GO:0007417]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; photoreceptor cell development [GO:0042461]; retina development in camera-type eye [GO:0060041]		axoneme assembly [GO:0035082]; central nervous system development [GO:0007417]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; photoreceptor cell development [GO:0042461]; retina development in camera-type eye [GO:0060041]		axoneme [GO:0005930]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; neuron projection [GO:0043005]		microtubule binding [GO:0008017]; protein kinase binding [GO:0019901]
d3dj1a__d1xz9a1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]; activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; pore complex [GO:0046930]; tight junction [GO:0070160]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; protein C-terminus binding [GO:0008022]; Ras GTPase binding [GO:0017016]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of protein localization to plasma membrane [GO:0061951]; negative regulation of cell migration [GO:0030336]; pore complex assembly [GO:0046931]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165]	activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of protein localization to plasma membrane [GO:0061951]; negative regulation of cell migration [GO:0030336]; pore complex assembly [GO:0046931]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell-cell adherens junction [GO:0005913]; cell-cell contact zone [GO:0044291]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; pore complex [GO:0046930]; tight junction [GO:0070160]	beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; protein C-terminus binding [GO:0008022]; Ras GTPase binding [GO:0017016]
d3dj1a__d2vsva1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]; activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; signal transduction [GO:0007165]	activation of GTPase activity [GO:0090630]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of Wnt signaling pathway [GO:0030178]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway [GO:0016055]	signal transduction [GO:0007165]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]	beta-catenin binding [GO:0008013]; protein C-terminus binding [GO:0008022]	
d3dj8a__d5ef8a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]
d3djca1_d2wusb1__1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	integral component of membrane [GO:0016021]; DNA binding [GO:0003677]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	DNA binding [GO:0003677]
d3djcb1_d5aqgc1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	coenzyme A biosynthetic process [GO:0015937]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3djce1_d2zf5o1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	coenzyme A biosynthetic process [GO:0015937]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d3djce1_d5uboa2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	coenzyme A biosynthetic process [GO:0015937]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3djcg1_d4h5ta1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	coenzyme A biosynthetic process [GO:0015937]	ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	cytoplasm [GO:0005737]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3djcg2_d4h5na1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	coenzyme A biosynthetic process [GO:0015937]	ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	cytoplasm [GO:0005737]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3djci1_d4fwpa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]; L-threonine catabolic process to propionate [GO:0070689]	coenzyme A biosynthetic process [GO:0015937]	L-threonine catabolic process to propionate [GO:0070689]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]
d3djci2_d2qw9b1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	coenzyme A biosynthetic process [GO:0015937]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d3djhb__d1hfoe___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	extracellular space [GO:0005615]; cytokine activity [GO:0005125]; dopachrome isomerase activity [GO:0004167]; phenylpyruvate tautomerase activity [GO:0050178]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	extracellular space [GO:0005615]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	cytokine activity [GO:0005125]; dopachrome isomerase activity [GO:0004167]; phenylpyruvate tautomerase activity [GO:0050178]
d3djoa__d3ljdb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]	RNA phosphodiester bond hydrolysis [GO:0090501]		extracellular region [GO:0005576]		endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]
d3djpb__d3i6ja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	RNA phosphodiester bond hydrolysis [GO:0090501]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d3djra__d3a4db___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3djsa__d5ayta___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3djsb__d2h1xd___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d3djxa__d9rsaa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; RNA phosphodiester bond hydrolysis [GO:0090501]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	RNA phosphodiester bond hydrolysis [GO:0090501]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d3dk0a__d1tz8a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3dk0b__d3cn4a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3dk2b__d2h6ub___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d3dk8a3_d1fecb3__1	Metazoa		Chordata		cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]
d3dkha1_d1x9rb___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		extraorganismal space [GO:0043245]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3dkha2_d1fa4a___1	Fungi		Ascomycota	Cyanobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		extraorganismal space [GO:0043245]	thylakoid membrane [GO:0042651]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3dkha3_d1aq8c2__1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	extraorganismal space [GO:0043245]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3dkhb2_d4a2da1__1	Fungi	Fungi	Ascomycota	Basidiomycota	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		extraorganismal space [GO:0043245]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3dkuc__d3whwa___1		Metazoa	Proteobacteria	Chordata	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTP diphosphatase activity [GO:0036219]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]; aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTPase activity [GO:0003924]; GTP diphosphatase activity [GO:0036219]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]
d3dkud__d5fska___1		Metazoa	Proteobacteria	Chordata	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTP diphosphatase activity [GO:0036219]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]; aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTPase activity [GO:0003924]; GTP diphosphatase activity [GO:0036219]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]
d3dkuh__d1g0sb___1			Proteobacteria	Proteobacteria	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]	cytosol [GO:0005829]; ADP-ribose diphosphatase activity [GO:0047631]; ADP-sugar diphosphatase activity [GO:0019144]; magnesium ion binding [GO:0000287]; nucleoside phosphate metabolic process [GO:0006753]; response to heat [GO:0009408]; ribose phosphate metabolic process [GO:0019693]		nucleoside phosphate metabolic process [GO:0006753]; response to heat [GO:0009408]; ribose phosphate metabolic process [GO:0019693]		cytosol [GO:0005829]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]	ADP-ribose diphosphatase activity [GO:0047631]; ADP-sugar diphosphatase activity [GO:0019144]; magnesium ion binding [GO:0000287]
d3dl5b1_d3nu0a___1		Metazoa		Chordata		cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3dl5c1_d3qlyb1__1		Fungi		Ascomycota		dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]		dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d3dl5d1_d3eeka1__1		Fungi		Ascomycota		dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]		dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d3dl5d2_d5x5qc___1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]		aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]		cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3dl9a2_d5gnma___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; vitamin D3 25-hydroxylase activity [GO:0030343]; calcitriol biosynthetic process from calciol [GO:0036378]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; response to cesium ion [GO:0010164]; response to ionizing radiation [GO:0010212]; vitamin D metabolic process [GO:0042359]; vitamin metabolic process [GO:0006766]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	calcitriol biosynthetic process from calciol [GO:0036378]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; response to cesium ion [GO:0010164]; response to ionizing radiation [GO:0010212]; vitamin D metabolic process [GO:0042359]; vitamin metabolic process [GO:0006766]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; vitamin D3 25-hydroxylase activity [GO:0030343]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3dlle1_d2qbgg2__1			Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	
d3dlll1_d1vqon1__1			Deinococcus-Thermus	Euryarchaeota	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytosolic large ribosomal subunit [GO:0022625]	ribosome [GO:0005840]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d3dlln1_d2qbcq1__1			Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	
d3dllo1_d2qbir1__1			Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]	
d3dlna__d1a99c___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; putrescine binding [GO:0019810]; putrescine transport [GO:0015847]	modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	putrescine transport [GO:0015847]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	putrescine binding [GO:0019810]
d3dlna__d5m8hh___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cytoplasm [GO:0005737]; histidine biosynthetic process [GO:0000105]	modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	histidine biosynthetic process [GO:0000105]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d3dlta__d5tgla___1		Fungi	Firmicutes	Mucoromycota	carboxylic ester hydrolase activity [GO:0052689]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]			carboxylic ester hydrolase activity [GO:0052689]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d3dlxa2_d2nrcd2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; adipose tissue development [GO:0060612]; brain development [GO:0007420]; cellular ketone body metabolic process [GO:0046950]; heart development [GO:0007507]; ketone body catabolic process [GO:0046952]; ketone catabolic process [GO:0042182]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	adipose tissue development [GO:0060612]; brain development [GO:0007420]; cellular ketone body metabolic process [GO:0046950]; heart development [GO:0007507]; ketone body catabolic process [GO:0046952]; ketone catabolic process [GO:0042182]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	mitochondrion [GO:0005739]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]
d3dmia__d2hv4a___1		Fungi	Bacillariophyta (diatoms)	Ascomycota	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3dmja2_d3u3gb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d3dmmb1_d3nh7l1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; dorsal aorta morphogenesis [GO:0035912]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]
d3dmpa1_d1upfa___1			Proteobacteria	Apicomplexa	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]			GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]
d3dmpd1_d1qb8a___1			Proteobacteria		GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	adenine phosphoribosyltransferase activity [GO:0003999]; nucleotide binding [GO:0000166]; nucleoside metabolic process [GO:0009116]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	nucleoside metabolic process [GO:0009116]			GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	adenine phosphoribosyltransferase activity [GO:0003999]; nucleotide binding [GO:0000166]
d3dmta2_d1u8fp2__1		Metazoa		Chordata	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]	glycosome [GO:0020015]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]
d3dmtb2_d2czcb2__1				Euryarchaeota	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycosome [GO:0020015]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	4-hydroxy-tetrahydrodipicolinate reductase [GO:0008839]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3dmtd2_d1nq5q2__1				Firmicutes	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glycosome [GO:0020015]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3dmva__d2heaa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3dmva__d3c7ya___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3dn9a__d3sssf1__1			Cyanobacteria	Cyanobacteria		identical protein binding [GO:0042802]						identical protein binding [GO:0042802]
d3dn9c__d2a1bc___1			Cyanobacteria	Cyanobacteria								
d3dn9d1_d3sssb1__1			Cyanobacteria	Cyanobacteria		identical protein binding [GO:0042802]						identical protein binding [GO:0042802]
d3dnca1_d2a10f___1			Cyanobacteria	Cyanobacteria								
d3dngb__d4gaab2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cytoplasm [GO:0005737]; leukotriene-A4 hydrolase activity [GO:0004463]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; leukotriene biosynthetic process [GO:0019370]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	leukotriene biosynthetic process [GO:0019370]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	leukotriene-A4 hydrolase activity [GO:0004463]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]
d3dnza__d5laba1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3do0a__d1os0a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3do0a__d6enca2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3do2a__d5ni4c2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3do4a__d2g2pb___1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	periplasmic space [GO:0042597]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]
d3do7a1_d1leib2__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3do7b1_d4ibqc___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d3dogd1_d3lq5b2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3dogd1_d4eosd1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d3dogd2_d3blrb2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3doja2_d1yvek1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytosol [GO:0005829]; 3-hydroxybutyrate dehydrogenase activity [GO:0003858]; glyoxylate reductase (NADP) activity [GO:0030267]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	response to oxidative stress [GO:0006979]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytosol [GO:0005829]	chloroplast [GO:0009507]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; glyoxylate reductase (NADP) activity [GO:0030267]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]
d3doka2_d3alya___1				Crenarchaeota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d3dola2_d1hjrc___1				Proteobacteria	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; Holliday junction resolvase complex [GO:0048476]; crossover junction endodeoxyribonuclease activity [GO:0008821]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; recombinational repair [GO:0000725]; response to radiation [GO:0009314]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	recombinational repair [GO:0000725]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; Holliday junction resolvase complex [GO:0048476]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	crossover junction endodeoxyribonuclease activity [GO:0008821]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d3dosc__d4xoac1__1			Proteobacteria	Proteobacteria	capsule [GO:0042603]; extracellular region [GO:0005576]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]		cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	capsule [GO:0042603]; extracellular region [GO:0005576]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d3dose__d2jkjc1__1			Proteobacteria	Proteobacteria	capsule [GO:0042603]; extracellular region [GO:0005576]	pilus [GO:0009289]			capsule [GO:0042603]; extracellular region [GO:0005576]	pilus [GO:0009289]		
d3doyb__d3f5of___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]; acyl-CoA hydrolase activity [GO:0047617]; acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	acyl-CoA hydrolase activity [GO:0047617]
d3doyc__d5buwa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3dozb__d5szvd___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	thiolester hydrolase activity [GO:0016790]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	thiolester hydrolase activity [GO:0016790]
d3dp0a__d5egkc___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	thiolester hydrolase activity [GO:0016790]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	thiolester hydrolase activity [GO:0016790]
d3dp0c__d2xemc___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	
d3dp1b__d3teab___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]
d3dp1c__d1wn3e___1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	thiolester hydrolase activity [GO:0016790]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	thiolester hydrolase activity [GO:0016790]
d3dp1e__d1vh5b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]; menaquinone biosynthetic process [GO:0009234]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	menaquinone biosynthetic process [GO:0009234]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]
d3dp1f__d3az9i___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	hydro-lyase activity [GO:0016836]
d3dp2a__d4qd8c___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	cytosol [GO:0005829]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]
d3dp2d__d1ylib___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]; acyl-CoA hydrolase activity [GO:0047617]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]; acyl-CoA metabolic process [GO:0006637]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	acyl-CoA metabolic process [GO:0006637]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	acyl-CoA hydrolase activity [GO:0047617]; fatty-acyl-CoA binding [GO:0000062]; long-chain fatty acyl-CoA binding [GO:0036042]
d3dp2d__d3azbc___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	hydro-lyase activity [GO:0016836]
d3dp3d__d4keha___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]
d3dp3e__d1wm6b___1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	thiolester hydrolase activity [GO:0016790]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	thiolester hydrolase activity [GO:0016790]
d3dp5a1_d2ce0a___1		Viridiplantae	Proteobacteria	Streptophyta	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	chloroplast thylakoid lumen [GO:0009543]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem I [GO:0009773]		photosynthetic electron transport in photosystem I [GO:0009773]		chloroplast thylakoid lumen [GO:0009543]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3dp6c__d5on1a___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]
d3dp8a__d3q29c___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3dp8c__d3wafa___1			Proteobacteria	Deinococcus-Thermus	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	metal ion binding [GO:0046872]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]	metal ion binding [GO:0046872]
d3dpea__d2oxza___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3dpfa__d3d0ia___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3dpsa__d5mx8a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	purine nucleoside metabolic process [GO:0042278]	cytoplasm [GO:0005737]		uridine phosphorylase activity [GO:0004850]	purine-nucleoside phosphorylase activity [GO:0004731]
d3dq0a1_d1v97b6__1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular space [GO:0005615]; cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cytokinin metabolic process [GO:0009690]	xanthine catabolic process [GO:0009115]	extracellular space [GO:0005615]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d3dq0a1_d4ml8c1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular space [GO:0005615]; cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]	cytokinin metabolic process [GO:0009690]	cytokinin metabolic process [GO:0009690]	extracellular space [GO:0005615]		cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]
d3dr4d1_d1asfa___1			Proteobacteria	Proteobacteria	GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase activity [GO:0102933]; O antigen biosynthetic process [GO:0009243]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	O antigen biosynthetic process [GO:0009243]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase activity [GO:0102933]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d3drba1_d3m10a1__1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3drba2_d1htor2__1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3drbb1_d1u6ra1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]	cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	extracellular space [GO:0005615]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3drbb2_d2bvcb2__1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3drca__d4h97a1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3dreb1_d3l2ed1__1	Metazoa	Metazoa	Chordata	Annelida	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	phosphocreatine biosynthetic process [GO:0046314]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3drna__d2gt5a1__1		Metazoa	Crenarchaeota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; copper ion binding [GO:0005507]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]	thioredoxin peroxidase activity [GO:0008379]	copper ion binding [GO:0005507]
d3drna__d6gsxa2__1		Metazoa	Crenarchaeota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	thioredoxin peroxidase activity [GO:0008379]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d3drra3_d3kkra1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell [GO:0043657]; viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell [GO:0043657]; viral nucleocapsid [GO:0019013]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d3drwa1_d4xckb___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; ADP-specific phosphofructokinase activity [GO:0043844]; magnesium ion binding [GO:0000287]; phosphofructokinase activity [GO:0008443]; fructose metabolic process [GO:0006000]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]	fructose metabolic process [GO:0006000]; glycolytic process [GO:0006096]	D-ribose catabolic process [GO:0019303]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ADP-specific phosphofructokinase activity [GO:0043844]; magnesium ion binding [GO:0000287]; phosphofructokinase activity [GO:0008443]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d3drwb__d1ua4a___1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ADP-specific phosphofructokinase activity [GO:0043844]; magnesium ion binding [GO:0000287]; phosphofructokinase activity [GO:0008443]; fructose metabolic process [GO:0006000]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; ADP-specific glucokinase activity [GO:0043843]; glucokinase activity [GO:0004340]; magnesium ion binding [GO:0000287]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	fructose metabolic process [GO:0006000]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ADP-specific phosphofructokinase activity [GO:0043844]; magnesium ion binding [GO:0000287]; phosphofructokinase activity [GO:0008443]	ADP-specific glucokinase activity [GO:0043843]; glucokinase activity [GO:0004340]; magnesium ion binding [GO:0000287]
d3drzb__d5a6rd___1	Metazoa	Metazoa	Chordata	Chordata	Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; cullin family protein binding [GO:0097602]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]; viral process [GO:0016032]	Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; cullin family protein binding [GO:0097602]; identical protein binding [GO:0042802]; cell projection organization [GO:0030030]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; positive regulation of cilium assembly [GO:0045724]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]; viral process [GO:0016032]	cell projection organization [GO:0030030]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; positive regulation of cilium assembly [GO:0045724]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]	Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]	cullin family protein binding [GO:0097602]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]	cullin family protein binding [GO:0097602]; identical protein binding [GO:0042802]
d3ds5b__d2m8na2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3dsca__d1s8eb___1			Euryarchaeota	Euryarchaeota	3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]; double-strand break repair [GO:0006302]	3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]; double-strand break repair [GO:0006302]	double-strand break repair [GO:0006302]	double-strand break repair [GO:0006302]			3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]	3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]
d3dsda__d3psnb___1		Metazoa	Euryarchaeota	Chordata	3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]; double-strand break repair [GO:0006302]	cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer complex [GO:0030904]; retromer, cargo-selective complex [GO:0030906]; metal ion binding [GO:0046872]; endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]	double-strand break repair [GO:0006302]	endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]		cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer, cargo-selective complex [GO:0030906]; retromer complex [GO:0030904]	3'-5' exonuclease activity [GO:0008408]; DNA end binding [GO:0045027]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; Y-form DNA binding [GO:0000403]	metal ion binding [GO:0046872]
d3dsza__d3i0aa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d3dt4c1_d2zcia1__1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; gluconeogenesis [GO:0006094]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	gluconeogenesis [GO:0006094]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]	GTP binding [GO:0005525]; manganese ion binding [GO:0030145]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]
d3dtbb1_d2fahb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]; aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	aging [GO:0007568]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to potassium ion starvation [GO:0051365]; cellular response to retinoic acid [GO:0071300]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; internal protein amino acid acetylation [GO:0006475]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to interleukin-6 [GO:0070741]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to methionine [GO:1904640]; response to starvation [GO:0042594]	cellular response to dexamethasone stimulus [GO:0071549]; cellular response to ethanol [GO:0071361]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; eggshell formation [GO:0030703]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ morphogenesis [GO:0048562]; gluconeogenesis [GO:0006094]; glucose catabolic process to lactate via pyruvate [GO:0019661]; glycerol biosynthetic process from pyruvate [GO:0046327]; glycerol catabolic process [GO:0019563]; hepatocyte differentiation [GO:0070365]; kidney interstitial fibroblast differentiation [GO:0072071]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]; lipid catabolic process [GO:0016042]; NADH regeneration [GO:0006735]; oviposition [GO:0018991]; positive regulation of cAMP-mediated signaling [GO:0043950]; post-translational protein modification [GO:0043687]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; regulation of gluconeogenesis [GO:0006111]; regulation of viral process [GO:0050792]; response to cAMP [GO:0051591]; response to lipid [GO:0033993]; response to starvation [GO:0042594]; vitellogenesis [GO:0007296]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	carboxylic acid binding [GO:0031406]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; nucleoside diphosphate kinase activity [GO:0004550]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; phosphoenolpyruvate carboxykinase activity [GO:0004611]	GTP binding [GO:0005525]; inosine kinase activity [GO:0008906]; lactate dehydrogenase activity [GO:0004457]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; phosphoenolpyruvate carboxykinase (GTP) activity [GO:0004613]; protein-disulfide reductase activity [GO:0047134]
d3dtpc1_d1mr8b___1	Metazoa	Metazoa	Chordata	Chordata	muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; sarcomere [GO:0030017]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actin-dependent ATPase activity [GO:0030898]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]; adult heart development [GO:0007512]; ATP metabolic process [GO:0046034]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy in response to stress [GO:0014898]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; regulation of heart rate [GO:0002027]; regulation of slow-twitch skeletal muscle fiber contraction [GO:0031449]; regulation of the force of heart contraction [GO:0002026]; regulation of the force of skeletal muscle contraction [GO:0014728]; skeletal muscle contraction [GO:0003009]; striated muscle contraction [GO:0006941]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	adult heart development [GO:0007512]; ATP metabolic process [GO:0046034]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy in response to stress [GO:0014898]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; regulation of heart rate [GO:0002027]; regulation of slow-twitch skeletal muscle fiber contraction [GO:0031449]; regulation of the force of heart contraction [GO:0002026]; regulation of the force of skeletal muscle contraction [GO:0014728]; skeletal muscle contraction [GO:0003009]; striated muscle contraction [GO:0006941]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	muscle myosin complex [GO:0005859]; myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; sarcomere [GO:0030017]; stress fiber [GO:0001725]; Z disc [GO:0030018]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	actin-dependent ATPase activity [GO:0030898]; actin filament binding [GO:0051015]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; microfilament motor activity [GO:0000146]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d3dtub1_d2b08b2__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3dtub1_d3ehbb1__1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3dtud1_d1ic0a___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	metal ion binding [GO:0046872]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]		copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	metal ion binding [GO:0046872]
d3dtxb1_d4y4fd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3dufa__d1qpba2__1		Fungi	Firmicutes	Ascomycota	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	glycolytic process [GO:0006096]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d3dufc__d2vk8a1__1		Fungi	Firmicutes	Ascomycota	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	glycolytic process [GO:0006096]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d3duff1_d4c7va2__1			Firmicutes	Firmicutes	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	glycolytic process [GO:0006096]				pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d3duff2_d1tkcb3__1		Fungi	Firmicutes	Ascomycota	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]	pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d3dufh1_d2ez4b2__1			Firmicutes	Firmicutes	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	glycolytic process [GO:0006096]				pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d3dufh1_d5femb1__1		Fungi	Firmicutes	Ascomycota	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	glycolytic process [GO:0006096]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3dufh2_d1x80b2__1		Metazoa	Firmicutes	Chordata	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]		mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]
d3duha1_d3b5hb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]; cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]	acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]	acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]	cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]
d3duhb1_d2xacx___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]; cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]	cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; natural killer cell activation [GO:0030101]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002860]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell activation [GO:0051135]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 17 cell lineage commitment [GO:2000330]; positive regulation of T-helper 17 type immune response [GO:2000318]; positive regulation of T-helper 1 type immune response [GO:0002827]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cytokine biosynthetic process [GO:0042035]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; response to UV-B [GO:0010224]; sensory perception of pain [GO:0019233]; sexual reproduction [GO:0019953]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; T-helper cell differentiation [GO:0042093]	blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-12 complex [GO:0043514]; interleukin-23 complex [GO:0070743]; late endosome lumen [GO:0031906]; receptor complex [GO:0043235]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytokine activity [GO:0005125]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; interleukin-12 alpha subunit binding [GO:0042164]; interleukin-12 receptor binding [GO:0005143]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]
d3duia__d4avve___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular space [GO:0005615]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d3durb__d5edxa___1	Metazoa	Metazoa	Chordata	Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]		
d3durc__d4ei6b2__1	Metazoa		Chordata									
d3dusd__d1yntd1__1	Metazoa		Chordata	Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]		IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]
d3duuc__d2f54k1__1	Metazoa	Metazoa	Chordata	Chordata		cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]		cytoplasm [GO:0005737]		
d3duuc__d5ksva2__1	Metazoa	Metazoa	Chordata	Chordata		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of membrane [GO:0016021]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; macrophage migration inhibitory factor receptor complex [GO:0035692]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; NOS2-CD74 complex [GO:0035693]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; vacuole [GO:0005773]; amyloid-beta binding [GO:0001540]; CD4 receptor binding [GO:0042609]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; macrophage migration inhibitory factor binding [GO:0035718]; MHC class II protein binding [GO:0042289]; MHC class II protein binding, via antigen binding groove [GO:0042658]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase binding [GO:0050998]; protein folding chaperone [GO:0044183]; activation of MAPK activity [GO:0000187]; antigen processing and presentation of endogenous antigen [GO:0019883]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell population proliferation [GO:0008283]; chaperone cofactor-dependent protein refolding [GO:0051085]; defense response [GO:0006952]; immunoglobulin mediated immune response [GO:0016064]; intracellular protein transport [GO:0006886]; leukocyte migration [GO:0050900]; macrophage migration inhibitory factor signaling pathway [GO:0035691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of peptide secretion [GO:0002792]; negative regulation of T cell differentiation [GO:0045581]; negative thymic T cell selection [GO:0045060]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of kinase activity [GO:0033674]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of macrophage migration inhibitory factor signaling pathway [GO:2000448]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of viral entry into host cell [GO:0046598]; positive thymic T cell selection [GO:0045059]; prostaglandin biosynthetic process [GO:0001516]; protein heterotetramerization [GO:0051290]; protein trimerization [GO:0070206]; protein-containing complex assembly [GO:0065003]; regulation of macrophage activation [GO:0043030]; signal transduction [GO:0007165]; T cell selection [GO:0045058]		activation of MAPK activity [GO:0000187]; antigen processing and presentation of endogenous antigen [GO:0019883]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cell population proliferation [GO:0008283]; chaperone cofactor-dependent protein refolding [GO:0051085]; defense response [GO:0006952]; immunoglobulin mediated immune response [GO:0016064]; intracellular protein transport [GO:0006886]; leukocyte migration [GO:0050900]; macrophage migration inhibitory factor signaling pathway [GO:0035691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of peptide secretion [GO:0002792]; negative regulation of T cell differentiation [GO:0045581]; negative thymic T cell selection [GO:0045060]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of kinase activity [GO:0033674]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of macrophage migration inhibitory factor signaling pathway [GO:2000448]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of viral entry into host cell [GO:0046598]; positive thymic T cell selection [GO:0045059]; prostaglandin biosynthetic process [GO:0001516]; protein-containing complex assembly [GO:0065003]; protein heterotetramerization [GO:0051290]; protein trimerization [GO:0070206]; regulation of macrophage activation [GO:0043030]; signal transduction [GO:0007165]; T cell selection [GO:0045058]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; cytoplasm [GO:0005737]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of membrane [GO:0016021]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; macrophage migration inhibitory factor receptor complex [GO:0035692]; membrane [GO:0016020]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; NOS2-CD74 complex [GO:0035693]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; vacuole [GO:0005773]		amyloid-beta binding [GO:0001540]; CD4 receptor binding [GO:0042609]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; macrophage migration inhibitory factor binding [GO:0035718]; MHC class II protein binding [GO:0042289]; MHC class II protein binding, via antigen binding groove [GO:0042658]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase binding [GO:0050998]; protein folding chaperone [GO:0044183]
d3dv0b2_d3exef2__1		Metazoa	Firmicutes	Chordata	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d3dv0d1_d3exg21__1		Metazoa	Firmicutes	Chordata	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d3dv0h2_d3exgz2__1		Metazoa	Firmicutes	Chordata	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d3dv2a__d5ts2a1__1				Proteobacteria		cytoplasm [GO:0005737]; [citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]		coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]		[citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d3dv4a__d1t5wa1__1	Metazoa	Metazoa	Chordata	Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d3dv6b__d4kq3l2__1	Metazoa		Chordata									
d3dvaa__d1ybha2__1		Viridiplantae	Firmicutes	Streptophyta	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]	glycolytic process [GO:0006096]	isoleucine biosynthetic process [GO:0009097]; response to herbicide [GO:0009635]; valine biosynthetic process [GO:0009099]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3dvac__d1q6za3__1			Firmicutes	Proteobacteria	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	glycolytic process [GO:0006096]	mandelate catabolic process [GO:0019596]			pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3dvad1_d1itzc1__1		Viridiplantae	Firmicutes	Streptophyta	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	glycolytic process [GO:0006096]	pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	calcium ion binding [GO:0005509]; cobalt ion binding [GO:0050897]; manganese ion binding [GO:0030145]; transketolase activity [GO:0004802]
d3dvad1_d4zp1c3__1			Firmicutes	Proteobacteria	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	glycolytic process [GO:0006096]				pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d3dvaf1_d2fwna3__1			Firmicutes	Proteobacteria	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	glycolytic process [GO:0006096]	mandelate catabolic process [GO:0019596]			pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3dvag__d4k9ma1__1			Firmicutes	Proteobacteria	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	glycolytic process [GO:0006096]	mandelate catabolic process [GO:0019596]			pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3dvga1_d5t0yg1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3dvgb2_d1kegh1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3dvgx2_d1eo6a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; ATPase binding [GO:0051117]; microtubule binding [GO:0008017]; SNARE binding [GO:0000149]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; intra-Golgi vesicle-mediated transport [GO:0006891]; macroautophagy [GO:0016236]; negative regulation of proteasomal protein catabolic process [GO:1901799]; positive regulation of ATPase activity [GO:0032781]; protein transport [GO:0015031]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; intra-Golgi vesicle-mediated transport [GO:0006891]; macroautophagy [GO:0016236]; negative regulation of proteasomal protein catabolic process [GO:1901799]; positive regulation of ATPase activity [GO:0032781]; protein transport [GO:0015031]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATPase binding [GO:0051117]; microtubule binding [GO:0008017]; SNARE binding [GO:0000149]; ubiquitin protein ligase binding [GO:0031625]
d3dvna1_d1i1ac1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3dvnh1_d1hyyl3__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3dvnu2_d5dpsa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; synapse [GO:0045202]; beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; chemical synaptic transmission [GO:0007268]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein targeting [GO:0006605]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; chemical synaptic transmission [GO:0007268]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein targeting [GO:0006605]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; synapse [GO:0045202]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d3dvnv__d4rmaa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]
d3dvsx__d1sioc___1	Fungi		Ascomycota	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3dvtf__d5wofc1__1	Metazoa		Arthropoda	Apicomplexa	cell [GO:0005623]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]; disordered domain specific binding [GO:0097718]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein homodimerization activity [GO:0042803]; actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; oogenesis [GO:0048477]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; sperm individualization [GO:0007291]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; wing disc development [GO:0035220]	cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; microtubule motor activity [GO:0003777]; motor activity [GO:0003774]; microtubule-based movement [GO:0007018]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]	actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; oogenesis [GO:0048477]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; sperm individualization [GO:0007291]; wing disc development [GO:0035220]	microtubule-based movement [GO:0007018]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]	cell [GO:0005623]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; microtubule [GO:0005874]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; dynein complex [GO:0030286]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]	disordered domain specific binding [GO:0097718]; dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; motor activity [GO:0003774]; protein homodimerization activity [GO:0042803]	dynein intermediate chain binding [GO:0045505]; dynein light intermediate chain binding [GO:0051959]; microtubule motor activity [GO:0003777]; motor activity [GO:0003774]
d3dvwa__d2f8fb2__1		Metazoa	Proteobacteria	Platyhelminthes	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]			glutathione transferase activity [GO:0004364]
d3dw1x__d1sh7b___1	Fungi		Ascomycota	Proteobacteria	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3dw8f__d4dhla2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]		chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]	extracellular region [GO:0005576]	GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]
d3dwfb__d2c29d___1	Metazoa	Viridiplantae	Chordata	Streptophyta	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; lung development [GO:0030324]; steroid metabolic process [GO:0008202]	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; nucleotide binding [GO:0000166]	lung development [GO:0030324]; steroid metabolic process [GO:0008202]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; nucleotide binding [GO:0000166]
d3dwyb__d4uiva___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	SWI/SNF complex [GO:0016514]; lysine-acetylated histone binding [GO:0070577]; nucleic acid binding [GO:0003676]; chromatin organization [GO:0006325]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	chromatin organization [GO:0006325]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	SWI/SNF complex [GO:0016514]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	lysine-acetylated histone binding [GO:0070577]; nucleic acid binding [GO:0003676]
d3dx2a1_d1w1a2___1	Metazoa		Arthropoda	Firmicutes	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]; sporulation resulting in formation of a cellular spore [GO:0030435]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]; sporulation resulting in formation of a cellular spore [GO:0030435]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]
d3dx3a1_d3bupa3__1	Metazoa	Metazoa	Arthropoda	Arthropoda	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d3dx4a1_d3cl6b___1	Metazoa		Arthropoda	Proteobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]
d3dx9a1_d1ifhh2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3dx9b1_d2hrph1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3dx9b2_d5usfc1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; tRNA aminoacylation for protein translation [GO:0006418]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	tRNA aminoacylation for protein translation [GO:0006418]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]
d3dx9c1_d1fskk1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3dx9c1_d3wyra2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; MHC class Ib receptor activity [GO:0032394]; transmembrane signaling receptor activity [GO:0004888]; cellular defense response [GO:0006968]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; positive regulation of cellular senescence [GO:2000774]; positive regulation of natural killer cell cytokine production [GO:0002729]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cellular defense response [GO:0006968]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; positive regulation of cellular senescence [GO:2000774]; positive regulation of natural killer cell cytokine production [GO:0002729]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class Ib receptor activity [GO:0032394]; transmembrane signaling receptor activity [GO:0004888]
d3dx9d1_d1igyc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3dxcc__d2x18b___1	Metazoa	Metazoa	Chordata	Chordata	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]; ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; intracellular signal transduction [GO:0035556]; mitochondrial genome maintenance [GO:0000002]; negative regulation of cellular senescence [GO:2000773]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid-beta clearance [GO:1900221]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	intracellular signal transduction [GO:0035556]; mitochondrial genome maintenance [GO:0000002]; negative regulation of cellular senescence [GO:2000773]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi lumen [GO:0005796]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]	cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]	acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d3dxdc__d2n0ya___1	Metazoa	Fungi	Chordata	Ascomycota	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]; nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid-beta clearance [GO:1900221]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi lumen [GO:0005796]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]	cytosol [GO:0005829]; nucleotide-excision repair factor 3 complex [GO:0000112]; nucleus [GO:0005634]; transcription factor TFIIH core complex [GO:0000439]; transcription factor TFIIH holo complex [GO:0005675]	acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]	phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-5-phosphate binding [GO:0010314]
d3dxea__d2d10c2__1	Metazoa	Metazoa	Chordata	Chordata	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid-beta clearance [GO:1900221]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi lumen [GO:0005796]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d3dxha__d3ridd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d3dxkd1_d3rsef___1	Metazoa	Metazoa	Chordata	Chordata	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	actin filament binding [GO:0051015]	actin filament binding [GO:0051015]
d3dxmb__d2d0pc3__1	Metazoa		Chordata	Proteobacteria	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]		Arp2/3 complex-mediated actin nucleation [GO:0034314]		Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]		actin filament binding [GO:0051015]	
d3dxsx__d2gcfa___1	Viridiplantae		Streptophyta	Cyanobacteria	endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; trans-Golgi network [GO:0005802]; ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; ethylene-activated signaling pathway [GO:0009873]; regulation of stomatal movement [GO:0010119]; response to ethylene [GO:0009723]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper ion import [GO:0015677]	ethylene-activated signaling pathway [GO:0009873]; regulation of stomatal movement [GO:0010119]; response to ethylene [GO:0009723]	copper ion import [GO:0015677]	endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; trans-Golgi network [GO:0005802]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]	ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]
d3dy3l__d5l5rs___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3dy3v__d1ofdb3__1	Fungi		Ascomycota	Cyanobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	3 iron, 4 sulfur cluster binding [GO:0051538]; glutamate synthase (ferredoxin) activity [GO:0016041]; metal ion binding [GO:0046872]; glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	3 iron, 4 sulfur cluster binding [GO:0051538]; glutamate synthase (ferredoxin) activity [GO:0016041]; metal ion binding [GO:0046872]
d3dy3v__d3d29y___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3dy41__d4qv9c___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3dy4c__d5lf7m___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3dy4e__d5fg9z___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3dy4i__d3unft___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3dy4j__d2pvac___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	penicillin amidase activity [GO:0008953]
d3dy4j__d4qlul___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3dy4m__d5jhsk___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3dy4q__d5l52s___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3dy8b2_d4llxa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3dyba__d4omcd1__1	Fungi	Metazoa	Ascomycota	Chordata	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d3dycb__d3szya___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]
d3dyla2_d1ro9a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d3dylb2_d1xp0a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	cytosol [GO:0005829]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]
d3dylb2_d3ecnb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to epidermal growth factor stimulus [GO:0071364]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; regulation of transcription, DNA-templated [GO:0006355]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cellular response to epidermal growth factor stimulus [GO:0071364]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]
d3dyma4_d2x05b5__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3dymb3_d3pzvc___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d3dymb5_d1ns7b1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d3dymc3_d3mv123__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3dymc4_d3dypd2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3dyna2_d3wi2b1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3dynb2_d4fcda1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3dyoa3_d4do6b1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	lactose catabolic process [GO:0005990]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	beta-galactosidase complex [GO:0009341]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d3dyoa5_d1yq2c4__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3dyoc1_d3k77c___1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	lactose catabolic process [GO:0005990]	base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	beta-galactosidase complex [GO:0009341]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]
d3dyod1_d2y6ga1__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3dyod1_d3acfa___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]
d3dyod4_d3e1f12__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3dypa2_d1jyye2__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3dypa4_d3mv142__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3dypc1_d4xzum___1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	lactose catabolic process [GO:0005990]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	beta-galactosidase complex [GO:0009341]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]
d3dypc4_d1jz0e1__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3dypd5_d3l4ya1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	lactose catabolic process [GO:0005990]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	beta-galactosidase complex [GO:0009341]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]
d3dyra1_d5g30a___1		Metazoa	Proteobacteria	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	protein disulfide oxidoreductase activity [GO:0015035]
d3dysa__d4llja1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3dz8a1_d2h92b___1	Metazoa		Chordata	Firmicutes	anchored component of synaptic vesicle membrane [GO:0098993]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dopaminergic synapse [GO:0098691]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; myosin V binding [GO:0031489]; antigen processing and presentation [GO:0019882]; intracellular protein transport [GO:0006886]; peptidyl-cysteine methylation [GO:0018125]; positive regulation of dopamine uptake involved in synaptic transmission [GO:0051586]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; Rab protein signal transduction [GO:0032482]; regulation of exocytosis [GO:0017157]; regulation of synaptic vesicle cycle [GO:0098693]; regulation of vesicle size [GO:0097494]; vesicle docking involved in exocytosis [GO:0006904]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; pyrimidine nucleotide metabolic process [GO:0006220]	antigen processing and presentation [GO:0019882]; intracellular protein transport [GO:0006886]; peptidyl-cysteine methylation [GO:0018125]; positive regulation of dopamine uptake involved in synaptic transmission [GO:0051586]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; Rab protein signal transduction [GO:0032482]; regulation of exocytosis [GO:0017157]; regulation of synaptic vesicle cycle [GO:0098693]; regulation of vesicle size [GO:0097494]; vesicle docking involved in exocytosis [GO:0006904]	pyrimidine nucleotide metabolic process [GO:0006220]	anchored component of synaptic vesicle membrane [GO:0098993]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dopaminergic synapse [GO:0098691]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; myosin V binding [GO:0031489]	ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]
d3dzfe__d3koua___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	plasma membrane [GO:0005886]; NAD glycohydrolase activity [GO:0061810]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]; metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD glycohydrolase activity [GO:0061810]; phosphorus-oxygen lyase activity [GO:0016849]
d3dzff__d3zwpd___1	Metazoa	Metazoa	Chordata	Mollusca	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	cytoplasmic vesicle [GO:0031410]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]
d3dzga__d3gc6b___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	plasma membrane [GO:0005886]; NAD glycohydrolase activity [GO:0061810]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]; metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD glycohydrolase activity [GO:0061810]; phosphorus-oxygen lyase activity [GO:0016849]
d3dzgb__d3zwwe___1	Metazoa	Metazoa	Chordata	Mollusca	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	cytoplasmic vesicle [GO:0031410]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]
d3dzwb__d3a0da___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d3e05b__d2zsua___1			Proteobacteria	Euryarchaeota	protein methyltransferase activity [GO:0008276]; cobalamin biosynthetic process [GO:0009236]	cytoplasm [GO:0005737]; spermidine synthase activity [GO:0004766]; spermidine biosynthetic process [GO:0008295]	cobalamin biosynthetic process [GO:0009236]	spermidine biosynthetic process [GO:0008295]		cytoplasm [GO:0005737]	protein methyltransferase activity [GO:0008276]	spermidine synthase activity [GO:0004766]
d3e05b__d3elwa___1			Proteobacteria		protein methyltransferase activity [GO:0008276]; cobalamin biosynthetic process [GO:0009236]	mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]	cobalamin biosynthetic process [GO:0009236]				protein methyltransferase activity [GO:0008276]	mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]
d3e05e__d1susa___1		Viridiplantae	Proteobacteria	Streptophyta	protein methyltransferase activity [GO:0008276]; cobalamin biosynthetic process [GO:0009236]	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]; lignin biosynthetic process [GO:0009809]	cobalamin biosynthetic process [GO:0009236]	lignin biosynthetic process [GO:0009809]			protein methyltransferase activity [GO:0008276]	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]
d3e08d__d3bk9a___1			Proteobacteria	Proteobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; tryptophan 2,3-dioxygenase activity [GO:0004833]; protein homotetramerization [GO:0051289]; tryptophan catabolic process to acetyl-CoA [GO:0019442]; tryptophan catabolic process to kynurenine [GO:0019441]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; tryptophan 2,3-dioxygenase activity [GO:0004833]; protein homotetramerization [GO:0051289]; tryptophan catabolic process to acetyl-CoA [GO:0019442]; tryptophan catabolic process to kynurenine [GO:0019441]	protein homotetramerization [GO:0051289]; tryptophan catabolic process to acetyl-CoA [GO:0019442]; tryptophan catabolic process to kynurenine [GO:0019441]	protein homotetramerization [GO:0051289]; tryptophan catabolic process to acetyl-CoA [GO:0019442]; tryptophan catabolic process to kynurenine [GO:0019441]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; tryptophan 2,3-dioxygenase activity [GO:0004833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; tryptophan 2,3-dioxygenase activity [GO:0004833]
d3e0bb1_d4or7a1__1			Firmicutes		dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	
d3e0od__d1xm0a2__1			Firmicutes		peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]		protein repair [GO:0030091]; response to oxidative stress [GO:0006979]				peptide-methionine (R)-S-oxide reductase activity [GO:0033743]	
d3e0ve1_d1e0ub1__1				Proteobacteria	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]; response to heat [GO:0009408]		glycolytic process [GO:0006096]; protein homotetramerization [GO:0051289]; response to heat [GO:0009408]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d3e13x__d3gbab1__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]		cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d3e1f12_d1jyzi2__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3e1f13_d4duxa3__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3e1f14_d1bgmm1__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3e1f23_d5okra___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	6-phospho-beta-galactosidase activity [GO:0033920]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	6-phospho-beta-galactosidase activity [GO:0033920]
d3e1f34_d3vd7d2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3e1f35_d3bvva2__1		Metazoa	Proteobacteria	Arthropoda	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d3e1f43_d5g5ub1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	beta-galactosidase complex [GO:0009341]	cytoplasm [GO:0005737]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]
d3e1f43_d7taaa2__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	lactose catabolic process [GO:0005990]	carbohydrate catabolic process [GO:0016052]	beta-galactosidase complex [GO:0009341]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d3e1jc__d2jd8m___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d3e1jd__d2jd77___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d3e1je__d5d8xe___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1jh__d5hjfb___1			Proteobacteria	Cyanobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3e1jj__d3a9ql___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3e1jl__d3kx9a___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]
d3e1ld__d2v2ra___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3e1ld__d2yjke___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d3e1lf__d2jd6p___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d3e1lj__d2iy4y___1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3e1mc__d1xvdc___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3e1md__d2jd85___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d3e1mf__d5jklh___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3e1mh__d4cybe___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3e1mj__d3a68u___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3e1ml__d5d8pe___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1nb__d1l8id___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3e1nb__d2yjjb___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d3e1nc__d2w0oa___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3e1ni__d1nf4n___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1ni__d4toab___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1nl__d1fz1c___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3e1nl__d2z6ml___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3e1ob__d3wnwh___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3e1od__d5d8xb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1of__d1veqe___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3e1oh__d2d5kd1__1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3e1oj__d4todl___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1ok__d5d8od___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1pa__d1l8ha___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3e1pc__d1xsma___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3e1pc__d4dasw___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1pf__d3uoff___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1pg__d1l8ia___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3e1pg__d4toet___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1pi__d2fkzh___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1pk__d1mfrs___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1pl__d2z6md___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3e1qd__d4cmyg___1			Proteobacteria	Chlorobi	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d3e1qe__d1xmfc1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3e1qg__d5da5x___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]
d3e1qh__d1jtsx___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3e1qh__d5l89o___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]
d3e1qj__d5d8xt___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1qk__d4toav___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e1wa__d4yf6d1__1			Proteobacteria	Actinobacteria	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbon utilization [GO:0015976]			plasma membrane [GO:0005886]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3e27c__d1f9af___1			Firmicutes	Euryarchaeota	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]
d3e2cb__d3is7q___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3e2na__d5sxqb1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3e2pa1_d2hsec2__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d3e2pb1_d4h31a2__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d3e2pb2_d4h31a1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d3e2pj1_d1nbea1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d3e2pj2_d4anfa2__1			Euryarchaeota	Tenericutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d3e2pl1_d2fg7z1__1			Euryarchaeota	Bacteroidetes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]
d3e2pl1_d4amud1__1			Euryarchaeota	Tenericutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d3e2pl2_d1at1a1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d3e2pm1_d4nf2a1__1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d3e2pn1_d1r0ca1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d3e2ra2_d1tj2a2__1			Proteobacteria	Proteobacteria	cytoplasmic side of plasma membrane [GO:0009898]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]; proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	cytoplasmic side of plasma membrane [GO:0009898]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]; proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	cytoplasmic side of plasma membrane [GO:0009898]	cytoplasmic side of plasma membrane [GO:0009898]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; proline dehydrogenase activity [GO:0004657]; sequence-specific DNA binding [GO:0043565]
d3e2ta__d4etla___1	Metazoa		Chordata	Proteobacteria	neuron projection [GO:0043005]; iron ion binding [GO:0005506]; tryptophan 5-monooxygenase activity [GO:0004510]; aromatic amino acid family metabolic process [GO:0009072]; serotonin biosynthetic process [GO:0042427]	iron ion binding [GO:0005506]; phenylalanine 4-monooxygenase activity [GO:0004505]; L-phenylalanine catabolic process [GO:0006559]	aromatic amino acid family metabolic process [GO:0009072]; serotonin biosynthetic process [GO:0042427]	L-phenylalanine catabolic process [GO:0006559]	neuron projection [GO:0043005]		iron ion binding [GO:0005506]; tryptophan 5-monooxygenase activity [GO:0004510]	iron ion binding [GO:0005506]; phenylalanine 4-monooxygenase activity [GO:0004505]
d3e2ua__d4b6mb___1	Metazoa		Chordata		centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; intermediate filament [GO:0005882]; kinetochore [GO:0000776]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nuclear envelope [GO:0005635]; ruffle [GO:0001726]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116]; protein transport into plasma membrane raft [GO:0044861]		microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; positive regulation of microtubule polymerization [GO:0031116]; protein transport into plasma membrane raft [GO:0044861]		centrosome [GO:0005813]; cytoplasmic microtubule [GO:0005881]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; intermediate filament [GO:0005882]; kinetochore [GO:0000776]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule plus-end [GO:0035371]; nuclear envelope [GO:0005635]; ruffle [GO:0001726]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein homodimerization activity [GO:0042803]; tubulin binding [GO:0015631]; zinc ion binding [GO:0008270]	
d3e2xa__d1ylkb1__1			Proteobacteria	Actinobacteria	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbon utilization [GO:0015976]			plasma membrane [GO:0005886]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3e2xa__d2esfb___1			Proteobacteria	Proteobacteria	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	cytosol [GO:0005829]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbon utilization [GO:0015976]	carbon utilization [GO:0015976]		cytosol [GO:0005829]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3e2ya__d2ez2b___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; kynurenine-glyoxylate transaminase activity [GO:0047315]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]; kynurenine metabolic process [GO:0070189]	tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]; kynurenine metabolic process [GO:0070189]	tyrosine metabolic process [GO:0006570]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]		cysteine-S-conjugate beta-lyase activity [GO:0047804]; kynurenine-glyoxylate transaminase activity [GO:0047315]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]	tyrosine phenol-lyase activity [GO:0050371]
d3e31b__d3tenb___1			Proteobacteria	Crenarchaeota	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbonate dehydratase activity [GO:0004089]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; hydrogen sulfide biosynthetic process [GO:0070814]	carbon utilization [GO:0015976]	hydrogen sulfide biosynthetic process [GO:0070814]			carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d3e3ab1_d4wfja___1			Actinobacteria	Actinobacteria	peroxidase activity [GO:0004601]	1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; metal ion binding [GO:0046872]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]			peroxidase activity [GO:0004601]	1-alkyl-2-acetylglycerophosphocholine esterase activity [GO:0003847]; metal ion binding [GO:0046872]
d3e3ea__d1xwca___1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]; nucleus [GO:0005634]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]
d3e3eb__d4hs1a1__1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d3e3fa__d1ekjc___1		Viridiplantae	Proteobacteria	Streptophyta	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	chloroplast stroma [GO:0009570]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbon utilization [GO:0015976]	carbon utilization [GO:0015976]		chloroplast stroma [GO:0009570]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3e3ka__d4rnsd___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; aromatic compound catabolic process [GO:0019439]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	aromatic compound catabolic process [GO:0019439]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3e3kb__d1utba1__1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3e3qc__d3lvea___1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d3e3qf__d2qeja1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; monomeric IgA immunoglobulin complex [GO:0071748]; secretory dimeric IgA immunoglobulin complex [GO:0071752]; secretory IgA immunoglobulin complex [GO:0071751]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of respiratory burst [GO:0060267]; protein-chromophore linkage [GO:0018298]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]	antibacterial humoral response [GO:0019731]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of respiratory burst [GO:0060267]; protein-chromophore linkage [GO:0018298]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; monomeric IgA immunoglobulin complex [GO:0071748]; secretory dimeric IgA immunoglobulin complex [GO:0071752]; secretory IgA immunoglobulin complex [GO:0071751]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3e3qj__d1zlwl1__1	Metazoa		Chordata		T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]		T cell receptor complex [GO:0042101]			
d3e3qn__d4pjif1__1	Metazoa	Metazoa	Chordata	Chordata	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3e3sa__d1lr3a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]			cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]		
d3e472__d5l68s___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3e47e__d5dkiy___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3e47f__d5l5xh___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3e47i__d3e47m___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3e47j__d5l5du___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3e47k__d2gplq___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3e47n__d5l67p___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3e47o__d4qvqi___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3e47s__d4qwix___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3e47v__d4no6c___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3e5ha1_d721pa___1	Metazoa	Metazoa	Chordata	Chordata	ciliary basal body [GO:0036064]; ciliary rootlet [GO:0035253]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; intracellular protein transport [GO:0006886]; Rab protein signal transduction [GO:0032482]; toxin transport [GO:1901998]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	intracellular protein transport [GO:0006886]; Rab protein signal transduction [GO:0032482]; toxin transport [GO:1901998]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	ciliary basal body [GO:0036064]; ciliary rootlet [GO:0035253]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d3e5ia__d4l1ed___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3e5la1_d2ij7b___1			Actinobacteria	Actinobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]
d3e5ub1_d4zzlb___1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of protein secretion [GO:0050709]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transmembrane transport [GO:0034763]	regulation of transcription, DNA-templated [GO:0006355]	negative regulation of protein secretion [GO:0050709]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transmembrane transport [GO:0034763]		protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3e5ub2_d2bgcf2__1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; pathogenesis [GO:0009405]	regulation of transcription, DNA-templated [GO:0006355]	pathogenesis [GO:0009405]			DNA binding [GO:0003677]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3e5xa1_d5jaxa___1		Metazoa	Firmicutes	Chordata	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	regulation of transcription, DNA-templated [GO:0006355]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]	ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]
d3e5xb1_d3kcca1__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3e5xc1_d3mzha1__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3e5ya__d5co4b1__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; RNA binding [GO:0003723]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; tRNA methyltransferase activity [GO:0008175]	cytoplasm [GO:0005737]; RNA binding [GO:0003723]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; tRNA methyltransferase activity [GO:0008175]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	RNA binding [GO:0003723]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; tRNA methyltransferase activity [GO:0008175]	RNA binding [GO:0003723]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; tRNA methyltransferase activity [GO:0008175]
d3e60a2_d1wdkd2__1			Proteobacteria	Proteobacteria	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	fatty acid biosynthetic process [GO:0006633]	fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation multienzyme complex [GO:0036125]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d3e60b1_d2wkvd1__1			Proteobacteria	Proteobacteria	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3e60b2_d2cdha1__1			Proteobacteria	Proteobacteria	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d3e6bb1_d3of1a1__1		Fungi	Firmicutes	Ascomycota	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; cGMP-mediated signaling [GO:0019934]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation [GO:0061406]; positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation [GO:0036278]; protein localization to bud neck [GO:0097271]; regulation of cytoplasmic mRNA processing body assembly [GO:0010603]	regulation of transcription, DNA-templated [GO:0006355]	cGMP-mediated signaling [GO:0019934]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation [GO:0061406]; positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation [GO:0036278]; protein localization to bud neck [GO:0097271]; regulation of cytoplasmic mRNA processing body assembly [GO:0010603]		cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]
d3e6fb__d3b2ux1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d3e6ha1_d2bcka2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3e6ha2_d2f19h1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3e6hb__d3cvil1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3e6ka__d4mxra___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	metal ion binding [GO:0046872]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	metal ion binding [GO:0046872]
d3e6ka__d5efha___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]
d3e6rb__d3a9qv___1		Viridiplantae	Bacillariophyta (diatoms)	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3e6rb__d4xkuf___1			Bacillariophyta (diatoms)	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3e6rc__d1otka1__1			Bacillariophyta (diatoms)	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]	cytosol [GO:0005829]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]	
d3e6sa__d1mtyd___1			Bacillariophyta (diatoms)	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3e6sd__d3fi6a___1		Metazoa	Bacillariophyta (diatoms)	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3e6vb__d3tf3b___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d3e77a1_d1m0na___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; L-serine biosynthetic process [GO:0006564]; pyridoxine biosynthetic process [GO:0008615]	2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	L-serine biosynthetic process [GO:0006564]; pyridoxine biosynthetic process [GO:0008615]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]	2,2-dialkylglycine decarboxylase (pyruvate) activity [GO:0047432]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d3e7ab__d2a22a1__1	Metazoa		Chordata	Apicomplexa	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	cytosol [GO:0005829]; retromer complex [GO:0030904]; retrograde transport, endosome to Golgi [GO:0042147]	beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	retrograde transport, endosome to Golgi [GO:0042147]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	cytosol [GO:0005829]; retromer complex [GO:0030904]	cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]	
d3e7ia__d1d0cb___1	Metazoa	Metazoa	Chordata	Chordata	cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; actin binding [GO:0003779]; arginine binding [GO:0034618]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; cAMP-dependent protein kinase regulator activity [GO:0008603]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; nitric-oxide synthase binding [GO:0050998]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tetrahydrobiopterin binding [GO:0034617]; arginine catabolic process [GO:0006527]; cellular response to cytokine stimulus [GO:0071345]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; circadian rhythm [GO:0007623]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; prostaglandin secretion [GO:0032310]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	caveola [GO:0005901]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; arginine catabolic process [GO:0006527]; blood coagulation [GO:0007596]; cellular response to laminar fluid shear stress [GO:0071499]; mitochondrion organization [GO:0007005]; negative regulation of blood pressure [GO:0045776]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; positive regulation of guanylate cyclase activity [GO:0031284]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496]	arginine catabolic process [GO:0006527]; cellular response to cytokine stimulus [GO:0071345]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; circadian rhythm [GO:0007623]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; prostaglandin secretion [GO:0032310]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	arginine catabolic process [GO:0006527]; blood coagulation [GO:0007596]; cellular response to laminar fluid shear stress [GO:0071499]; mitochondrion organization [GO:0007005]; negative regulation of blood pressure [GO:0045776]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; positive regulation of guanylate cyclase activity [GO:0031284]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496]	cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	caveola [GO:0005901]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	actin binding [GO:0003779]; arginine binding [GO:0034618]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; cAMP-dependent protein kinase regulator activity [GO:0008603]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; nitric-oxide synthase binding [GO:0050998]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tetrahydrobiopterin binding [GO:0034617]	calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]
d3e81a__d4l6aa1__1		Metazoa	Bacteroidetes	Chordata	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]	lipopolysaccharide biosynthetic process [GO:0009103]	DNA replication [GO:0006260]; dUMP catabolic process [GO:0046079]; pyrimidine deoxyribonucleotide catabolic process [GO:0009223]; pyrimidine nucleoside catabolic process [GO:0046135]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]
d3e81b__d3l0cb___1		Metazoa	Bacteroidetes	Chordata	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]	lipopolysaccharide biosynthetic process [GO:0009103]	negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]		extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]
d3e81d__d3wk4a1__1		Metazoa	Bacteroidetes	Chordata	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipopolysaccharide biosynthetic process [GO:0009103]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3e84b__d2rara___1			Bacteroidetes	Bacteroidetes	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]	lipopolysaccharide biosynthetic process [GO:0009103]			cytosol [GO:0005829]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]
d3e84d__d1l8oa___1		Metazoa	Bacteroidetes	Chordata	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; phosphoserine phosphatase activity [GO:0004647]; protein homodimerization activity [GO:0042803]; dephosphorylation [GO:0016311]; in utero embryonic development [GO:0001701]; L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563]; response to mechanical stimulus [GO:0009612]; response to nutrient levels [GO:0031667]; response to testosterone [GO:0033574]	lipopolysaccharide biosynthetic process [GO:0009103]	dephosphorylation [GO:0016311]; in utero embryonic development [GO:0001701]; L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563]; response to mechanical stimulus [GO:0009612]; response to nutrient levels [GO:0031667]; response to testosterone [GO:0033574]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; phosphoserine phosphatase activity [GO:0004647]; protein homodimerization activity [GO:0042803]
d3e8mb__d3quqa1__1			Bacteroidetes	Bacteroidetes	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	lipopolysaccharide biosynthetic process [GO:0009103]				hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]
d3e8mc__d4hgre___1			Bacteroidetes	Bacteroidetes	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]			hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d3e8md__d3hych___1			Bacteroidetes	Proteobacteria	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]			hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d3e8rb__d3g42c___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d3e95c__d5f6ea___1		Metazoa	Apicomplexa	Chordata	nucleus [GO:0005634]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]; ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]
d3e96b__d1qo5e___1		Metazoa	Firmicutes	Chordata	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose binding [GO:0070061]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]; canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]		canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]		centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose binding [GO:0070061]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]
d3e9ba__d4cbyb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	A band [GO:0031672]; actomyosin [GO:0042641]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; neuromuscular junction [GO:0031594]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; Z disc [GO:0030018]; activating transcription factor binding [GO:0033613]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; potassium ion binding [GO:0030955]; promoter-specific chromatin binding [GO:1990841]; protein deacetylase activity [GO:0033558]; protein kinase binding [GO:0019901]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; SUMO transferase activity [GO:0019789]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to mechanical stimulus [GO:0071260]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of glycolytic process [GO:0045820]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; osteoblast development [GO:0002076]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of male mating behavior [GO:1902437]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deacetylation [GO:0006476]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein binding [GO:0043393]; regulation of skeletal muscle fiber development [GO:0048742]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to drug [GO:0042493]; response to interleukin-1 [GO:0070555]; skeletal system development [GO:0001501]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to mechanical stimulus [GO:0071260]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of glycolytic process [GO:0045820]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; osteoblast development [GO:0002076]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of male mating behavior [GO:1902437]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein binding [GO:0043393]; regulation of skeletal muscle fiber development [GO:0048742]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to drug [GO:0042493]; response to interleukin-1 [GO:0070555]; skeletal system development [GO:0001501]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	A band [GO:0031672]; actomyosin [GO:0042641]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; neuromuscular junction [GO:0031594]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; Z disc [GO:0030018]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	activating transcription factor binding [GO:0033613]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; potassium ion binding [GO:0030955]; promoter-specific chromatin binding [GO:1990841]; protein deacetylase activity [GO:0033558]; protein kinase binding [GO:0019901]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; SUMO transferase activity [GO:0019789]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3e9bc__d1ta1a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d3e9hc1_d5elod1__1			Firmicutes	Apicomplexa	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	lysyl-tRNA aminoacylation [GO:0006430]	lysyl-tRNA aminoacylation [GO:0006430]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; nucleic acid binding [GO:0003676]
d3e9id1_d1ph1a1__1			Firmicutes	Ciliophora	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]; protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]; telomere capping [GO:0016233]	lysyl-tRNA aminoacylation [GO:0006430]	telomere capping [GO:0016233]	cytoplasm [GO:0005737]	nuclear chromosome, telomeric region [GO:0000784]; protein-containing complex [GO:0032991]; telomere cap complex [GO:0000782]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]	protein heterodimerization activity [GO:0046982]; single-stranded telomeric DNA binding [GO:0043047]
d3e9pa__d4jk8b___1	Fungi	Metazoa	Ascomycota	Chordata	catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]; generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]	catalytic step 2 spliceosome [GO:0071013]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal tri-snRNP complex assembly [GO:0000244]	generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]	cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal tri-snRNP complex assembly [GO:0000244]	catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	catalytic step 2 spliceosome [GO:0071013]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]	K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]
d3e9pb__d5tera2__1	Fungi		Ascomycota		catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]; generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ea1a__d3ea3b___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]	phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]
d3ea1b__d2oogb1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]; lipid catabolic process [GO:0016042]	metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081]; lipid metabolic process [GO:0006629]	lipid catabolic process [GO:0016042]	lipid metabolic process [GO:0006629]	extracellular region [GO:0005576]		phosphatidylinositol diacylglycerol-lyase activity [GO:0004436]; phosphoric diester hydrolase activity [GO:0008081]	metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081]
d3ea5a__d3lbha___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; disordered domain specific binding [GO:0097718]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]; mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore complex assembly [GO:0051292]; phosphatidylcholine biosynthetic process [GO:0006656]; protein import into nucleus [GO:0006606]; protein targeting to membrane [GO:0006612]; regulation of protein desumoylation [GO:0060188]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore complex assembly [GO:0051292]; phosphatidylcholine biosynthetic process [GO:0006656]; protein import into nucleus [GO:0006606]; protein targeting to membrane [GO:0006612]; regulation of protein desumoylation [GO:0060188]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	disordered domain specific binding [GO:0097718]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d3ea5c__d1gina___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; disordered domain specific binding [GO:0097718]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]; mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore complex assembly [GO:0051292]; phosphatidylcholine biosynthetic process [GO:0006656]; protein import into nucleus [GO:0006606]; protein targeting to membrane [GO:0006612]; regulation of protein desumoylation [GO:0060188]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; 'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore complex assembly [GO:0051292]; phosphatidylcholine biosynthetic process [GO:0006656]; protein import into nucleus [GO:0006606]; protein targeting to membrane [GO:0006612]; regulation of protein desumoylation [GO:0060188]	'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	disordered domain specific binding [GO:0097718]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]	adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d3ea7a__d1trmb___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508]; response to nutrient [GO:0007584]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]
d3ea7a__d5c5ob___1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3ea8a__d1v2rt___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3ea8a__d4hi3a___1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3eadb__d2fwsa1__1	Metazoa	Metazoa	Arthropoda	Chordata	integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]; calcium:sodium antiporter activity [GO:0005432]; neuromuscular process controlling posture [GO:0050884]; phototransduction [GO:0007602]; response to endoplasmic reticulum stress [GO:0034976]	cell [GO:0005623]; integral component of plasma membrane [GO:0005887]; intrinsic component of plasma membrane [GO:0031226]; nucleoplasm [GO:0005654]; postsynapse [GO:0098794]; sarcolemma [GO:0042383]; ankyrin binding [GO:0030506]; calcium ion binding [GO:0005509]; calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration [GO:1905060]; calcium:sodium antiporter activity [GO:0005432]; calmodulin binding [GO:0005516]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; cell communication [GO:0007154]; cellular sodium ion homeostasis [GO:0006883]; positive regulation of bone mineralization [GO:0030501]; positive regulation of the force of heart contraction [GO:0098735]; response to muscle stretch [GO:0035994]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	neuromuscular process controlling posture [GO:0050884]; phototransduction [GO:0007602]; response to endoplasmic reticulum stress [GO:0034976]	calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; cell communication [GO:0007154]; cellular sodium ion homeostasis [GO:0006883]; positive regulation of bone mineralization [GO:0030501]; positive regulation of the force of heart contraction [GO:0098735]; response to muscle stretch [GO:0035994]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	integral component of membrane [GO:0016021]	cell [GO:0005623]; integral component of plasma membrane [GO:0005887]; intrinsic component of plasma membrane [GO:0031226]; nucleoplasm [GO:0005654]; postsynapse [GO:0098794]; sarcolemma [GO:0042383]	calcium:sodium antiporter activity [GO:0005432]; calcium ion binding [GO:0005509]	ankyrin binding [GO:0030506]; calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration [GO:1905060]; calcium:sodium antiporter activity [GO:0005432]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]
d3eadd__d2lt9a___1	Metazoa	Metazoa	Arthropoda	Chordata	integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]; calcium:sodium antiporter activity [GO:0005432]; neuromuscular process controlling posture [GO:0050884]; phototransduction [GO:0007602]; response to endoplasmic reticulum stress [GO:0034976]	cell [GO:0005623]; cell junction [GO:0030054]; cell projection [GO:0042995]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; intrinsic component of plasma membrane [GO:0031226]; microtubule [GO:0005874]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; calcium:cation antiporter activity [GO:0015368]; calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration [GO:1905060]; calcium:sodium antiporter activity [GO:0005432]; calmodulin binding [GO:0005516]; ion antiporter activity involved in regulation of postsynaptic membrane potential [GO:0099580]; metal ion binding [GO:0046872]; calcium ion export across plasma membrane [GO:1990034]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537]	neuromuscular process controlling posture [GO:0050884]; phototransduction [GO:0007602]; response to endoplasmic reticulum stress [GO:0034976]	calcium ion export across plasma membrane [GO:1990034]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537]	integral component of membrane [GO:0016021]	cell [GO:0005623]; cell junction [GO:0030054]; cell projection [GO:0042995]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; intrinsic component of plasma membrane [GO:0031226]; microtubule [GO:0005874]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	calcium:sodium antiporter activity [GO:0005432]; calcium ion binding [GO:0005509]	calcium:cation antiporter activity [GO:0015368]; calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration [GO:1905060]; calcium:sodium antiporter activity [GO:0005432]; calmodulin binding [GO:0005516]; ion antiporter activity involved in regulation of postsynaptic membrane potential [GO:0099580]; metal ion binding [GO:0046872]
d3eaka__d1kxvd___1		Metazoa		Chordata		extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]		carbohydrate catabolic process [GO:0016052]		extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3eaua__d2fzba___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; juxtaparanode region of axon [GO:0044224]; neuron projection [GO:0043005]; pinceau fiber [GO:1990031]; potassium channel complex [GO:0034705]; synapse [GO:0045202]; aldo-keto reductase (NADP) activity [GO:0004033]; ion channel binding [GO:0044325]; potassium channel regulator activity [GO:0015459]; voltage-gated potassium channel activity [GO:0005249]; myoblast differentiation [GO:0045445]; NADPH oxidation [GO:0070995]; oxidation-reduction process [GO:0055114]; protein heterooligomerization [GO:0051291]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	myoblast differentiation [GO:0045445]; NADPH oxidation [GO:0070995]; oxidation-reduction process [GO:0055114]; protein heterooligomerization [GO:0051291]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	axon [GO:0030424]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; juxtaparanode region of axon [GO:0044224]; neuron projection [GO:0043005]; pinceau fiber [GO:1990031]; potassium channel complex [GO:0034705]; synapse [GO:0045202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	aldo-keto reductase (NADP) activity [GO:0004033]; ion channel binding [GO:0044325]; potassium channel regulator activity [GO:0015459]; voltage-gated potassium channel activity [GO:0005249]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d3eb2b1_d4bk9b___1			Proteobacteria		lyase activity [GO:0016829]						lyase activity [GO:0016829]	
d3eb2c__d5vy5a___1		Metazoa	Proteobacteria	Chordata	lyase activity [GO:0016829]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]		glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]		I band [GO:0031674]; M band [GO:0031430]	lyase activity [GO:0016829]	fructose-bisphosphate aldolase activity [GO:0004332]
d3eb2d1_d2quud___1		Metazoa	Proteobacteria	Chordata	lyase activity [GO:0016829]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]		glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]		I band [GO:0031674]; M band [GO:0031430]	lyase activity [GO:0016829]	fructose-bisphosphate aldolase activity [GO:0004332]
d3eb7a2_d4arxc2__1			Firmicutes	Firmicutes	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]			signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d3eb7a3_d3k77h___1		Metazoa	Firmicutes	Chordata	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	sporulation resulting in formation of a cellular spore [GO:0030435]	base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]		ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]
d3eb7c3_d1kgyd___1		Metazoa	Firmicutes	Chordata	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	sporulation resulting in formation of a cellular spore [GO:0030435]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]		axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3ebsb1_d4nz2b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; (S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	(S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d3ebsc__d4egmd___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]		arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3ebsd__d2nnia___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; lipid hydroxylation [GO:0002933]; long-chain fatty acid biosynthetic process [GO:0042759]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; estrogen 16-alpha-hydroxylase activity [GO:0101020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; retinoic acid 4-hydroxylase activity [GO:0008401]; steroid hydroxylase activity [GO:0008395]
d3ebzb__d3spka___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]
d3ec0a__d4xx4a___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d3ec0b__d5ozba___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ecaa__d5i3za___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]; asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]	asparaginase activity [GO:0004067]; asparagine metabolic process [GO:0006528]	asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]	asparagine metabolic process [GO:0006528]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]	asparaginase activity [GO:0004067]
d3ecab__d5k45d___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]; asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]; asparaginase activity [GO:0004067]; asparagine metabolic process [GO:0006528]	asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]	asparagine metabolic process [GO:0006528]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cytoplasm [GO:0005737]	asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]	asparaginase activity [GO:0004067]
d3ecac__d1o7ja___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]; asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]	asparaginase activity [GO:0004067]; asparagine metabolic process [GO:0006528]	asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]	asparagine metabolic process [GO:0006528]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]	asparaginase activity [GO:0004067]
d3ecac__d5ot0c___1			Proteobacteria	Euryarchaeota	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]; asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]	asparaginase activity [GO:0004067]; cellular amino acid metabolic process [GO:0006520]	asparagine catabolic process [GO:0006530]; protein homotetramerization [GO:0051289]	cellular amino acid metabolic process [GO:0006520]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		asparaginase activity [GO:0004067]; identical protein binding [GO:0042802]	asparaginase activity [GO:0004067]
d3ecbb__d3m8oh1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ecia__d4zdva1__1	Metazoa	Metazoa	Chordata	Chordata	autolysosome [GO:0044754]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; microtubule [GO:0005874]; organelle membrane [GO:0031090]; synapse [GO:0045202]; microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; phospholipid binding [GO:0005543]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]	autolysosome [GO:0044754]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; microtubule [GO:0005874]; organelle membrane [GO:0031090]; synapse [GO:0045202]; microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; phospholipid binding [GO:0005543]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]	autolysosome [GO:0044754]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; microtubule [GO:0005874]; organelle membrane [GO:0031090]; synapse [GO:0045202]	autolysosome [GO:0044754]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; microtubule [GO:0005874]; organelle membrane [GO:0031090]; synapse [GO:0045202]	microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; phospholipid binding [GO:0005543]; ubiquitin protein ligase binding [GO:0031625]	microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; phospholipid binding [GO:0005543]; ubiquitin protein ligase binding [GO:0031625]
d3ecjb2_d4ghhb1__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3ecjc2_d1jc5e___1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	methylmalonyl-CoA epimerase activity [GO:0004493]					dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	methylmalonyl-CoA epimerase activity [GO:0004493]
d3ecka2_d1mpyb2__1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; toluene catabolic process [GO:0042203]		toluene catabolic process [GO:0042203]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]
d3eckb2_d1sp8d1__1			Actinobacteria		dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]						dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	
d3eckd1_d1kwcb2__1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]		aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]
d3ecla__d5v3vb___1	Metazoa		Chordata	Firmicutes	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen transport [GO:0015671]		oxygen transport [GO:0015671]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d3ecma__d3sl6d___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to epidermal growth factor stimulus [GO:0071364]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; regulation of transcription, DNA-templated [GO:0006355]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cellular response to epidermal growth factor stimulus [GO:0071364]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; regulation of transcription, DNA-templated [GO:0006355]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d3ecna__d5b25c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to epidermal growth factor stimulus [GO:0071364]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; neuronal cell body [GO:0043025]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity [GO:0048101]; calmodulin binding [GO:0005516]; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity [GO:0004117]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotory behavior [GO:0007626]; monocyte differentiation [GO:0030224]; regulation of dopamine metabolic process [GO:0042053]; response to amphetamine [GO:0001975]; serotonin metabolic process [GO:0042428]; visual learning [GO:0008542]	cAMP catabolic process [GO:0006198]; cellular response to epidermal growth factor stimulus [GO:0071364]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; regulation of transcription, DNA-templated [GO:0006355]	apoptotic process [GO:0006915]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotory behavior [GO:0007626]; monocyte differentiation [GO:0030224]; regulation of dopamine metabolic process [GO:0042053]; response to amphetamine [GO:0001975]; serotonin metabolic process [GO:0042428]; visual learning [GO:0008542]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; neuronal cell body [GO:0043025]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity [GO:0048101]; calmodulin binding [GO:0005516]; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity [GO:0004117]; metal ion binding [GO:0046872]
d3ecxa__d4nzia___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]		apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3ecza__d1hacd___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3ed0d__d3azbg___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	hydro-lyase activity [GO:0016836]
d3ed0f__d3r32b___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]
d3edaa__d1gh0a___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3edba__d4h2lb___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3edca__d1bykb___1			Proteobacteria		cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]		negative regulation of transcription, DNA-templated [GO:0045892]		cytosol [GO:0005829]		bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]	
d3edca__d2x7xa___1			Proteobacteria	Bacteroidetes	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	integral component of membrane [GO:0016021]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay sensor kinase activity [GO:0000155]; sequence-specific DNA binding [GO:0043565]	negative regulation of transcription, DNA-templated [GO:0045892]		cytosol [GO:0005829]	integral component of membrane [GO:0016021]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]	DNA-binding transcription factor activity [GO:0003700]; phosphorelay sensor kinase activity [GO:0000155]; sequence-specific DNA binding [GO:0043565]
d3edda1_d1wzma1__1			Bacteroidetes	Firmicutes	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d3edda2_d3hg5b1__1		Metazoa	Bacteroidetes	Chordata	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d3edda2_d4b3ld___1			Bacteroidetes	Firmicutes	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3edda3_d1jaea1__1		Metazoa	Bacteroidetes	Arthropoda	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]			cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3edea1_d3edda1__1			Bacteroidetes	Bacteroidetes	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d3edea2_d1ukpc___1		Viridiplantae	Bacteroidetes	Streptophyta	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]			cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d3edea2_d2bs9h2__1			Bacteroidetes	Firmicutes	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]			cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d3edeb1_d1rlea5__1			Bacteroidetes		cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]	
d3edfb1_d4x42c___1			Bacteroidetes		cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3edfb2_d4oozb1__1		Metazoa	Bacteroidetes	Arthropoda	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]	metabolic process [GO:0008152]			cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]
d3edfb3_d3tv8b2__1		Metazoa	Bacteroidetes	Chordata	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d3edjb2_d1v3mb4__1			Bacteroidetes	Firmicutes	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3edka1_d1qhoa1__1			Bacteroidetes	Firmicutes	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]	glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3edzb__d4h82d___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3ee2a2_d4g9hb1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	transferase activity [GO:0016740]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	transferase activity [GO:0016740]
d3ee2b1_d3vi5a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d3ee5a__d4c2sa1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]
d3ee5c__d1h4ea___1	Metazoa		Chordata	Proteobacteria	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]; bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process [GO:1902758]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	cytoplasm [GO:0005737]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; molybdenum cofactor guanylyltransferase activity [GO:0061603]
d3eeca__d4gocc1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]; cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]
d3eecb__d5aekn___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d3eeea__d6aq3d___1			Firmicutes	Heterolobosea	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; TRAPP complex [GO:0030008]; Golgi vesicle transport [GO:0048193]	signal transduction [GO:0007165]	Golgi vesicle transport [GO:0048193]	integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; TRAPP complex [GO:0030008]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d3eeeb__d6aq3e___1			Firmicutes	Heterolobosea	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; TRAPP complex [GO:0030008]; Golgi vesicle transport [GO:0048193]	signal transduction [GO:0007165]	Golgi vesicle transport [GO:0048193]	integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; TRAPP complex [GO:0030008]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d3eeec__d6aq3b___1			Firmicutes	Heterolobosea	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; TRAPP complex [GO:0030008]; Golgi vesicle transport [GO:0048193]	signal transduction [GO:0007165]	Golgi vesicle transport [GO:0048193]	integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; TRAPP complex [GO:0030008]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d3eeib__d1u1fb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]	cytosol [GO:0005829]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]
d3eejb1_d4elhh1__1	Fungi		Ascomycota	Firmicutes	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d3eeka1_d1ia1a___1	Fungi	Fungi	Ascomycota	Ascomycota	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3eelb1_d3f0ux___1	Fungi		Ascomycota		dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]		dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]	
d3eelb1_d4kakb___1	Fungi	Metazoa	Ascomycota	Chordata	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3eeoa__d5lr6d___1		Metazoa	Proteobacteria	Chordata	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	DNA restriction-modification system [GO:0009307]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d3eesa__d1xsba1__1		Metazoa	Proteobacteria	Chordata	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; DNA repair [GO:0006281]	mitochondrial matrix [GO:0005759]; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity [GO:0008803]; GTP binding [GO:0005525]; apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; nucleobase-containing compound metabolic process [GO:0006139]	DNA repair [GO:0006281]	apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; nucleobase-containing compound metabolic process [GO:0006139]		mitochondrial matrix [GO:0005759]	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity [GO:0008803]; GTP binding [GO:0005525]
d3eevc__d4kpza2__1			Proteobacteria	Proteobacteria	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]	transferase activity [GO:0016740]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d3eewc__d4b4wa2__1				Proteobacteria		methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; nucleotide binding [GO:0000166]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]		histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]				methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; nucleotide binding [GO:0000166]
d3ef3a__d4p93b___1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	carboxymethylenebutenolidase activity [GO:0008806]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]	extracellular region [GO:0005576]		cutinase activity [GO:0050525]	carboxymethylenebutenolidase activity [GO:0008806]
d3ef4b__d4dp0x___1		Viridiplantae	Proteobacteria	Streptophyta	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3ef4c__d4q8bb2__1			Proteobacteria	Firmicutes	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3efdl2_d3skna2__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d3efdl2_d4orzc___1		Metazoa		Chordata		caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]		ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]
d3efha1_d2c4kd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]; enzyme inhibitor activity [GO:0004857]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; purine nucleobase metabolic process [GO:0006144]; purine nucleotide biosynthetic process [GO:0006164]; pyrimidine nucleotide biosynthetic process [GO:0006221]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; urate biosynthetic process [GO:0034418]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribose phosphate diphosphokinase complex [GO:0002189]	cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; ribose phosphate diphosphokinase activity [GO:0004749]	enzyme inhibitor activity [GO:0004857]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]
d3efua__d2d2qa3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d3eg4a__d3tk8a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]
d3eggb__d1nnwa___1	Metazoa		Chordata	Euryarchaeota	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]		cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]	
d3egmc1_d5l8gi1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]
d3egmd1_d4m33a___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3egme1_d5l8by___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]
d3egmf1_d1bcfk___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3egva1_d2nxea1__1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; protein methyltransferase activity [GO:0008276]	cytoplasm [GO:0005737]; protein methyltransferase activity [GO:0008276]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	protein methyltransferase activity [GO:0008276]	protein methyltransferase activity [GO:0008276]
d3egwa2_d1ti6a1__1			Proteobacteria		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]	
d3eh3b2_d3fyeb2__1			Deinococcus-Thermus	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d3eh3b2_d4enza1__1		Metazoa	Deinococcus-Thermus	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]		cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d3eh4b2_d1wa1x1__1			Deinococcus-Thermus	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]		copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3eh8a2_d1n3fa___1	Fungi	Viridiplantae	Ascomycota	Chlorophyta	mitochondrion [GO:0005739]; endonuclease activity [GO:0004519]; intron homing [GO:0006314]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	chloroplast [GO:0009507]; endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; intron homing [GO:0006314]	intron homing [GO:0006314]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	intron homing [GO:0006314]	mitochondrion [GO:0005739]	chloroplast [GO:0009507]	endonuclease activity [GO:0004519]	endonuclease activity [GO:0004519]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3ehbb1_d2j5wa2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d3ehbd__d5u1rg2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ehwb__d4a6ah___1	Metazoa		Chordata	Actinobacteria	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d3ehwz__d2qlpb___1	Metazoa		Chordata	Actinobacteria	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d3ei5a__d2fn6b___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; polysaccharide biosynthetic process [GO:0000271]	lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	polysaccharide biosynthetic process [GO:0000271]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d3ei7a1_d2dgkb___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]
d3ei7b1_d2yctb___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	tyrosine phenol-lyase activity [GO:0050371]; tyrosine metabolic process [GO:0006570]	lysine biosynthetic process via diaminopimelate [GO:0009089]; systemic acquired resistance, salicylic acid mediated signaling pathway [GO:0009862]	tyrosine metabolic process [GO:0006570]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; L,L-diaminopimelate aminotransferase activity [GO:0010285]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	tyrosine phenol-lyase activity [GO:0050371]
d3eicd1_d1vyad___1		Viridiplantae		Streptophyta	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]
d3eika1_d3ocia2__1	Fungi	Fungi	Microsporidia	Microsporidia	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]; DNA-templated transcription, initiation [GO:0006352]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]; DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]	DNA-templated transcription, initiation [GO:0006352]			DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]
d3eina1_d3pgtb2__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; DDT-dehydrochlorinase activity [GO:0018833]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to toxic substance [GO:0009636]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; response to toxic substance [GO:0009636]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	DDT-dehydrochlorinase activity [GO:0018833]; glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3eina2_d1b8xa1__1	Metazoa	Metazoa	Arthropoda	Platyhelminthes	cytoplasm [GO:0005737]; DDT-dehydrochlorinase activity [GO:0018833]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to toxic substance [GO:0009636]	glutathione transferase activity [GO:0004364]	glutathione metabolic process [GO:0006749]; response to toxic substance [GO:0009636]		cytoplasm [GO:0005737]		DDT-dehydrochlorinase activity [GO:0018833]; glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d3eiya__d1obwc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; membrane [GO:0016020]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; triphosphatase activity [GO:0050355]; zinc ion binding [GO:0008270]
d3eiza1_d4z71a1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3ej2a1_d4luga___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; lipid storage [GO:0019915]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	lipid storage [GO:0019915]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3ej8a__d4nsea___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; arginine binding [GO:0034618]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin binding [GO:0034617]; arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; circadian rhythm [GO:0007623]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of leukocyte mediated cytotoxicity [GO:0001912]; prostaglandin secretion [GO:0032310]; protein targeting to peroxisome [GO:0006625]; regulation of cell population proliferation [GO:0042127]; regulation of cellular respiration [GO:0043457]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	caveola [GO:0005901]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; arginine catabolic process [GO:0006527]; blood coagulation [GO:0007596]; cellular response to laminar fluid shear stress [GO:0071499]; mitochondrion organization [GO:0007005]; negative regulation of blood pressure [GO:0045776]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; positive regulation of guanylate cyclase activity [GO:0031284]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496]	arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; circadian rhythm [GO:0007623]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of leukocyte mediated cytotoxicity [GO:0001912]; prostaglandin secretion [GO:0032310]; protein targeting to peroxisome [GO:0006625]; regulation of cell population proliferation [GO:0042127]; regulation of cellular respiration [GO:0043457]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	arginine catabolic process [GO:0006527]; blood coagulation [GO:0007596]; cellular response to laminar fluid shear stress [GO:0071499]; mitochondrion organization [GO:0007005]; negative regulation of blood pressure [GO:0045776]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; positive regulation of guanylate cyclase activity [GO:0031284]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	caveola [GO:0005901]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	arginine binding [GO:0034618]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin binding [GO:0034617]	calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]
d3ejbc2_d1klpa___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; acyl-CoA metabolic process [GO:0006637]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	acyl-CoA metabolic process [GO:0006637]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]
d3ejbe2_d2lola___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	acyl carrier activity [GO:0000036]
d3ejbg2_d2m5ra1__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	mitochondrial matrix [GO:0005759]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]
d3ejdc2_d4dxel1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	acyl carrier activity [GO:0000036]
d3ejea2_d2ehsa___1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; phosphopantetheine binding [GO:0031177]; lipid A biosynthetic process [GO:0009245]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; phosphopantetheine binding [GO:0031177]
d3ejee2_d2mr7a1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	hydrolase activity, acting on ester bonds [GO:0016788]; phosphopantetheine binding [GO:0031177]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	hydrolase activity, acting on ester bonds [GO:0016788]; phosphopantetheine binding [GO:0031177]
d3ejga__d1yd9a1__1		Metazoa		Chordata	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	Barr body [GO:0001740]; chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	Barr body [GO:0001740]; chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]
d3ejia__d2f0oa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3ejma1_d1s59c___1		Viridiplantae		Streptophyta	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]		chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ejmb1_d1vyaf___1		Viridiplantae		Streptophyta	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]
d3ejpa1_d2cc0a1__1	Metazoa		Arthropoda	Actinobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]
d3ejqa2_d1k1xa1__1	Metazoa		Arthropoda	Euryarchaeota	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; carbohydrate binding [GO:0030246]
d3ejsa1_d3s6ob___1	Metazoa		Arthropoda	Proteobacteria	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]
d3ejua3_d1nsxb1__1	Metazoa		Arthropoda	Firmicutes	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	galactose metabolic process [GO:0006012]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]		alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d3ejwb__d4jb2a___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]				ATP-binding cassette (ABC) transporter complex [GO:0043190]			
d3ejxb2_d1u1wb1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	lysine biosynthetic process via diaminopimelate [GO:0009089]	pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]		diaminopimelate epimerase activity [GO:0008837]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]
d3ejxf2_d3g7kb2__1	Viridiplantae		Streptophyta	Firmicutes	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	methylitaconate delta-isomerase activity [GO:0050100]; cofactor catabolic process [GO:0051187]	lysine biosynthetic process via diaminopimelate [GO:0009089]	cofactor catabolic process [GO:0051187]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]		diaminopimelate epimerase activity [GO:0008837]	methylitaconate delta-isomerase activity [GO:0050100]
d3ejzd1_d5do2l2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3ejzd2_d3b2uh1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d3ejzf1_d5ushe1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3ek1e__d2ej6a___1			Proteobacteria	Deinococcus-Thermus	succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; gamma-aminobutyric acid catabolic process [GO:0009450]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	gamma-aminobutyric acid catabolic process [GO:0009450]				succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3ek1h__d2euhd___1			Proteobacteria	Firmicutes	succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; gamma-aminobutyric acid catabolic process [GO:0009450]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]	gamma-aminobutyric acid catabolic process [GO:0009450]				succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]
d3ek6d__d2we5a___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; ATP binding [GO:0005524]; UMP kinase activity [GO:0033862]; 'de novo' CTP biosynthetic process [GO:0044210]; UDP biosynthetic process [GO:0006225]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]; arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	'de novo' CTP biosynthetic process [GO:0044210]; UDP biosynthetic process [GO:0006225]	arginine metabolic process [GO:0006525]; carbamoyl phosphate catabolic process [GO:0035975]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; UMP kinase activity [GO:0033862]	ATP binding [GO:0005524]; carbamate kinase activity [GO:0008804]
d3ekca__d1pkqj1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	aging [GO:0007568]; cell adhesion [GO:0007155]; regulation of immune response [GO:0050776]; response to folic acid [GO:0051593]; response to lipid [GO:0033993]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; myelin sheath [GO:0043209]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	signaling receptor binding [GO:0005102]
d3ekma2_d2gkja2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]	cytosol [GO:0005829]	diaminopimelate epimerase activity [GO:0008837]	diaminopimelate epimerase activity [GO:0008837]
d3ekmb1_d1t6ka2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	lysine biosynthetic process via diaminopimelate [GO:0009089]	pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]		diaminopimelate epimerase activity [GO:0008837]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]
d3ekmb2_d2pw0a1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	intramolecular oxidoreductase activity, transposing C=C bonds [GO:0016863]; propionate catabolic process, 2-methylcitrate cycle [GO:0019629]	lysine biosynthetic process via diaminopimelate [GO:0009089]	propionate catabolic process, 2-methylcitrate cycle [GO:0019629]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]		diaminopimelate epimerase activity [GO:0008837]	intramolecular oxidoreductase activity, transposing C=C bonds [GO:0016863]
d3ekmb2_d4ik0b2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]	cytosol [GO:0005829]	diaminopimelate epimerase activity [GO:0008837]	diaminopimelate epimerase activity [GO:0008837]
d3ekmd2_d4q60b1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	4-hydroxyproline epimerase activity [GO:0047580]	lysine biosynthetic process via diaminopimelate [GO:0009089]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]		diaminopimelate epimerase activity [GO:0008837]	4-hydroxyproline epimerase activity [GO:0047580]
d3ekme2_d1s7jb___1	Viridiplantae		Streptophyta	Firmicutes	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	catalytic activity [GO:0003824]; biosynthetic process [GO:0009058]	lysine biosynthetic process via diaminopimelate [GO:0009089]	biosynthetic process [GO:0009058]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]		diaminopimelate epimerase activity [GO:0008837]	catalytic activity [GO:0003824]
d3ekme2_d3ejxb1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	lysine biosynthetic process via diaminopimelate [GO:0009089]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]	diaminopimelate epimerase activity [GO:0008837]	diaminopimelate epimerase activity [GO:0008837]
d3ekmf1_d1w61b1__1	Viridiplantae		Streptophyta		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; membrane [GO:0016020]; proline racemase activity [GO:0018112]; multicellular organism development [GO:0007275]	lysine biosynthetic process via diaminopimelate [GO:0009089]	multicellular organism development [GO:0007275]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; membrane [GO:0016020]	diaminopimelate epimerase activity [GO:0008837]	proline racemase activity [GO:0018112]
d3ekpb__d4y39a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ekpd__d3t11a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ekpd__d5p0ea___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ekqb__d3er3e___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3eksa2_d3l6qa2__1	Metazoa		Arthropoda	Apicomplexa	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	ATP binding [GO:0005524]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]		actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]		ATP binding [GO:0005524]	ATP binding [GO:0005524]
d3ektc__d1bxqa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ekua2_d3gdqa1__1	Metazoa	Metazoa	Arthropoda	Chordata	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	blood microparticle [GO:0072562]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; zona pellucida receptor complex [GO:0002199]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; binding of sperm to zona pellucida [GO:0007339]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein refolding [GO:0042026]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	binding of sperm to zona pellucida [GO:0007339]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein refolding [GO:0042026]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	blood microparticle [GO:0072562]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; zona pellucida receptor complex [GO:0002199]	ATP binding [GO:0005524]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3ekva__d5tyrb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ekxa__d1j71a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ekxb__d4fs4b___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3ekyb__d2bb9a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ekyb__d4y3xa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3el0a__d2fivb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d3el1a__d2bpwb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3el2a2_d4h5wa2__1	Metazoa	Metazoa	Arthropoda	Chordata	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3el2a2_d5evza2__1	Metazoa	Metazoa	Arthropoda	Chordata	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	ATP binding [GO:0005524]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3el5a__d4djxb___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3el5b__d2bjua1__1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3el9a__d3vfab___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3elxa1_d5l8ib___1	Metazoa	Metazoa	Chordata	Chordata	bile acid binding [GO:0032052]; lipid binding [GO:0008289]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; lipid binding [GO:0008289]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; negative regulation of cell population proliferation [GO:0008285]; triglyceride catabolic process [GO:0019433]		lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; negative regulation of cell population proliferation [GO:0008285]; triglyceride catabolic process [GO:0019433]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	bile acid binding [GO:0032052]; lipid binding [GO:0008289]	lipid binding [GO:0008289]
d3elzc1_d4runb1__1	Metazoa	Metazoa	Chordata	Chordata	bile acid binding [GO:0032052]; lipid binding [GO:0008289]	extracellular region [GO:0005576]; odorant binding [GO:0005549]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]		response to stimulus [GO:0050896]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]	bile acid binding [GO:0032052]; lipid binding [GO:0008289]	odorant binding [GO:0005549]; small molecule binding [GO:0036094]
d3em0a1_d3zq3a___1	Metazoa	Metazoa	Chordata	Chordata	bile acid binding [GO:0032052]; lipid binding [GO:0008289]	small molecule binding [GO:0036094]					bile acid binding [GO:0032052]; lipid binding [GO:0008289]	small molecule binding [GO:0036094]
d3em1a1_d1nskr___1		Metazoa		Chordata	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]		cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]
d3em4a__d5oz4a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3em5b__d4c7fb2__1				Actinobacteria		beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				beta-N-acetylhexosaminidase activity [GO:0004563]
d3em5c__d3scsa___1		Viridiplantae		Streptophyta		extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d3em5d__d1uksa4__1				Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3em6a__d1proa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3em6b__d3ggah___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3emma__d2hnxa2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]		brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]		fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d3emsa__d1jnca___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d3emtb1_d1f6tb___1					ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3emya__d2qcia___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3emza__d1e5nb___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]		endo-1,4-beta-xylanase activity [GO:0031176]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]
d3enaa1_d4uogc___1		Metazoa		Arthropoda	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3enda__d5v71d1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]; actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]		actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]
d3endb__d2ew1a1__1		Metazoa		Chordata		cis-Golgi network [GO:0005801]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; intracellular membrane-bounded organelle [GO:0043231]; trans-Golgi network [GO:0005802]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; Rab protein signal transduction [GO:0032482]		Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; Rab protein signal transduction [GO:0032482]		cis-Golgi network [GO:0005801]; Golgi cisterna [GO:0031985]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; intracellular membrane-bounded organelle [GO:0043231]; trans-Golgi network [GO:0005802]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d3enga__d1oa7a___1	Fungi	Fungi	Ascomycota	Ascomycota	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]			cellulase activity [GO:0008810]	cellulase activity [GO:0008810]
d3enka__d1nnu.2__1			Proteobacteria	Apicomplexa	nucleotide binding [GO:0000166]; UDP-glucose 4-epimerase activity [GO:0003978]; galactose metabolic process [GO:0006012]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	galactose metabolic process [GO:0006012]	fatty acid biosynthetic process [GO:0006633]			nucleotide binding [GO:0000166]; UDP-glucose 4-epimerase activity [GO:0003978]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; nucleotide binding [GO:0000166]
d3enkb__d1mg0c2__1		Metazoa	Proteobacteria	Chordata	nucleotide binding [GO:0000166]; UDP-glucose 4-epimerase activity [GO:0003978]; galactose metabolic process [GO:0006012]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	galactose metabolic process [GO:0006012]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	nucleotide binding [GO:0000166]; UDP-glucose 4-epimerase activity [GO:0003978]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d3enla2_d2al1b2__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3enrb__d1diwa1__1	Viridiplantae		Streptophyta	Firmicutes	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d3eo0a1_d5l6yl2__1	Metazoa	Metazoa	Chordata	Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]
d3eo0c1_d4y4fh1__1	Metazoa	Metazoa	Chordata	Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d3eo0c1_d5ibub1__1	Metazoa		Chordata									
d3eo1a1_d1wipb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell development [GO:0048468]; cell-cell junction organization [GO:0045216]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; in utero embryonic development [GO:0001701]; inner ear development [GO:0048839]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell development [GO:0048468]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; inner ear development [GO:0048839]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3eo1a1_d5xajd1__1	Metazoa		Chordata		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell development [GO:0048468]; cell-cell junction organization [GO:0045216]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; in utero embryonic development [GO:0001701]; inner ear development [GO:0048839]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]		activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell development [GO:0048468]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; inner ear development [GO:0048839]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]		cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]	
d3eo1a2_d2cdeb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell development [GO:0048468]; cell-cell junction organization [GO:0045216]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; in utero embryonic development [GO:0001701]; inner ear development [GO:0048839]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell development [GO:0048468]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; inner ear development [GO:0048839]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3eo1d1_d1ottd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell development [GO:0048468]; cell-cell junction organization [GO:0045216]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; in utero embryonic development [GO:0001701]; inner ear development [GO:0048839]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell development [GO:0048468]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; inner ear development [GO:0048839]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3eo1g2_d2zchl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell development [GO:0048468]; cell-cell junction organization [GO:0045216]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; in utero embryonic development [GO:0001701]; inner ear development [GO:0048839]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell development [GO:0048468]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; inner ear development [GO:0048839]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3eo1j1_d1t1zb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell development [GO:0048468]; cell-cell junction organization [GO:0045216]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; in utero embryonic development [GO:0001701]; inner ear development [GO:0048839]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell development [GO:0048468]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; inner ear development [GO:0048839]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3eo1j2_d1i1ad2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell development [GO:0048468]; cell-cell junction organization [GO:0045216]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; in utero embryonic development [GO:0001701]; inner ear development [GO:0048839]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell development [GO:0048468]; detection of hypoxia [GO:0070483]; digestive tract development [GO:0048565]; embryonic neurocranium morphogenesis [GO:0048702]; face morphogenesis [GO:0060325]; female pregnancy [GO:0007565]; frontal suture morphogenesis [GO:0060364]; inner ear development [GO:0048839]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; mammary gland development [GO:0030879]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; odontogenesis [GO:0042476]; ossification involved in bone remodeling [GO:0043932]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of MAPK cascade [GO:0043408]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to laminar fluid shear stress [GO:0034616]; response to progesterone [GO:0032570]; salivary gland morphogenesis [GO:0007435]; secondary palate development [GO:0062009]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterine wall breakdown [GO:0042704]; wound healing [GO:0042060]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; T-tubule [GO:0030315]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]	
d3eo9l1_d5tlkc2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; extrinsic apoptotic signaling pathway [GO:0097191]; immunoglobulin mediated immune response [GO:0016064]; negative regulation of apoptotic process [GO:0043066]; negative regulation of T cell apoptotic process [GO:0070233]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell differentiation [GO:0045582]; response to ethanol [GO:0045471]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		cell surface receptor signaling pathway [GO:0007166]; extrinsic apoptotic signaling pathway [GO:0097191]; immunoglobulin mediated immune response [GO:0016064]; negative regulation of apoptotic process [GO:0043066]; negative regulation of T cell apoptotic process [GO:0070233]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell differentiation [GO:0045582]; response to ethanol [GO:0045471]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; transmembrane signaling receptor activity [GO:0004888]
d3eo9l1_d5vsil1__1												
d3eo9l2_d5d7jg1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3eoal2_d5grza1__1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]		cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]		cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	
d3eooa__d2r82a1__1				Firmicutes		ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; pyruvate metabolic process [GO:0006090]		pyruvate metabolic process [GO:0006090]				ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]
d3eooc__d1vbga1__1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; photosynthesis [GO:0015979]; pyruvate metabolic process [GO:0006090]		photosynthesis [GO:0015979]; pyruvate metabolic process [GO:0006090]		chloroplast [GO:0009507]		ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]
d3eoof__d1f8ib___1				Actinobacteria		cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]; zymogen binding [GO:0035375]; cellular response to hypoxia [GO:0071456]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; maintenance of symbiont tolerance to host environment [GO:0075141]; pathogenesis [GO:0009405]; response to acetate [GO:0010034]; response to acidic pH [GO:0010447]; response to fatty acid [GO:0070542]; response to host immune response [GO:0052572]; tricarboxylic acid cycle [GO:0006099]		cellular response to hypoxia [GO:0071456]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; maintenance of symbiont tolerance to host environment [GO:0075141]; pathogenesis [GO:0009405]; response to acetate [GO:0010034]; response to acidic pH [GO:0010447]; response to fatty acid [GO:0070542]; response to host immune response [GO:0052572]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]; zymogen binding [GO:0035375]
d3eotl1_d4p2ck___1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3epra1_d1wvia___1			Firmicutes	Firmicutes	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]						hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	
d3eq8a1_d2hu7a1__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type peptidase activity [GO:0008236]
d3eq8a2_d2wugb___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]; aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]		aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]
d3eq9a1_d2hu7b1__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type peptidase activity [GO:0008236]
d3eqle__d4g7ho___1			Deinococcus-Thermus	Deinococcus-Thermus	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]; transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]	transcription, DNA-templated [GO:0006351]			DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; ribonucleoside binding [GO:0032549]
d3eqza1_d2iynb___1			Proteobacteria	Proteobacteria	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]	phosphorelay signal transduction system [GO:0000160]	phosphate ion transport [GO:0006817]; regulation of DNA-templated transcription, initiation [GO:2000142]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		bacterial-type RNA polymerase holo enzyme binding [GO:0001108]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3er5e__d1aidb___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3erna1_d4c8ec___1			Proteobacteria	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d3erne1_d4c8ib___1			Proteobacteria	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d3erta__d2i4pb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transcriptional preinitiation complex [GO:0097550]; transcriptionally active chromatin [GO:0035327]; ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor activity [GO:0030284]; estrogen receptor binding [GO:0030331]; estrogen response element binding [GO:0034056]; identical protein binding [GO:0042802]; nitric-oxide synthase regulator activity [GO:0030235]; nuclear receptor activity [GO:0004879]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; steroid binding [GO:0005496]; TBP-class protein binding [GO:0017025]; TFIIB-class transcription factor binding [GO:0001093]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; androgen metabolic process [GO:0008209]; antral ovarian follicle growth [GO:0001547]; cellular response to estradiol stimulus [GO:0071392]; cellular response to estrogen stimulus [GO:0071391]; chromatin remodeling [GO:0006338]; epithelial cell development [GO:0002064]; epithelial cell proliferation involved in mammary gland duct elongation [GO:0060750]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; male gonad development [GO:0008584]; mammary gland alveolus development [GO:0060749]; mammary gland branching involved in pregnancy [GO:0060745]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; protein deubiquitination [GO:0016579]; protein localization to chromatin [GO:0071168]; regulation of apoptotic process [GO:0042981]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of inflammatory response [GO:0050727]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; signal transduction [GO:0007165]; stem cell differentiation [GO:0048863]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]; uterus development [GO:0060065]; vagina development [GO:0060068]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]; activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	androgen metabolic process [GO:0008209]; antral ovarian follicle growth [GO:0001547]; cellular response to estradiol stimulus [GO:0071392]; cellular response to estrogen stimulus [GO:0071391]; chromatin remodeling [GO:0006338]; epithelial cell development [GO:0002064]; epithelial cell proliferation involved in mammary gland duct elongation [GO:0060750]; intracellular estrogen receptor signaling pathway [GO:0030520]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; male gonad development [GO:0008584]; mammary gland alveolus development [GO:0060749]; mammary gland branching involved in pregnancy [GO:0060745]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; protein deubiquitination [GO:0016579]; protein localization to chromatin [GO:0071168]; regulation of apoptotic process [GO:0042981]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of inflammatory response [GO:0050727]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; signal transduction [GO:0007165]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; uterus development [GO:0060065]; vagina development [GO:0060068]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; transcriptionally active chromatin [GO:0035327]; transcriptional preinitiation complex [GO:0097550]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]	ATPase binding [GO:0051117]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor activity [GO:0030284]; estrogen receptor binding [GO:0030331]; estrogen response element binding [GO:0034056]; identical protein binding [GO:0042802]; nitric-oxide synthase regulator activity [GO:0030235]; nuclear receptor activity [GO:0004879]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; steroid binding [GO:0005496]; TBP-class protein binding [GO:0017025]; TFIIB-class transcription factor binding [GO:0001093]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]
d3erxa__d2pcya___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3es6b1_d3n40f2__1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	host cell cytoplasm [GO:0030430]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; negative regulation of cell population proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	host cell cytoplasm [GO:0030430]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; virion membrane [GO:0055036]	protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3es7a1_d2ggec2__1			Firmicutes	Firmicutes	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]					lyase activity [GO:0016829]; metal ion binding [GO:0046872]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3es7b1_d3dfym1__1			Firmicutes	Thermotogae	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]		cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]			lyase activity [GO:0016829]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d3es8a1_d4gypb1__1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]		D-glucarate catabolic process [GO:0042838]			lyase activity [GO:0016829]; metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3es8b2_d4mggb2__1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	amino acid binding [GO:0016597]; hydro-lyase activity [GO:0016836]; isomerase activity [GO:0016853]; magnesium ion binding [GO:0000287]; alpha-amino acid metabolic process [GO:1901605]; cellular response to amino acid stimulus [GO:0071230]		alpha-amino acid metabolic process [GO:1901605]; cellular response to amino acid stimulus [GO:0071230]			lyase activity [GO:0016829]; metal ion binding [GO:0046872]	amino acid binding [GO:0016597]; hydro-lyase activity [GO:0016836]; isomerase activity [GO:0016853]; magnesium ion binding [GO:0000287]
d3es8c1_d1pdza2__1		Metazoa	Firmicutes	Arthropoda	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		phosphopyruvate hydratase complex [GO:0000015]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3es8c2_d2ptya1__1			Firmicutes		lyase activity [GO:0016829]; metal ion binding [GO:0046872]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3es8c2_d3ct2b2__1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]		cellular amino acid catabolic process [GO:0009063]			lyase activity [GO:0016829]; metal ion binding [GO:0046872]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d3es8d2_d2fkpa1__1			Firmicutes	Deinococcus-Thermus	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]		menaquinone biosynthetic process [GO:0009234]			lyase activity [GO:0016829]; metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3es8e1_d2ggeh2__1			Firmicutes	Firmicutes	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]					lyase activity [GO:0016829]; metal ion binding [GO:0046872]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3esaa__d5fv4c___1	Fungi	Metazoa	Ascomycota	Chordata	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	cutinase activity [GO:0050525]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d3esda__d1xzba___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	cutinase activity [GO:0050525]	cutinase activity [GO:0050525]
d3esfa2_d4f2nj2__1					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3esfb2_d3ak1a2__1				Crenarchaeota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3eska1_d2c2lb1__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3esob__d1tfpb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	clathrin-coated vesicle [GO:0030136]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; yolk [GO:0060417]; hormone activity [GO:0005179]; hormone binding [GO:0042562]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; small molecule binding [GO:0036094]; thyroid hormone binding [GO:0070324]; oocyte growth [GO:0001555]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; purine nucleobase metabolic process [GO:0006144]; response to virus [GO:0009615]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	oocyte growth [GO:0001555]; protein-containing complex assembly [GO:0065003]; protein tetramerization [GO:0051262]; purine nucleobase metabolic process [GO:0006144]; response to virus [GO:0009615]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	clathrin-coated vesicle [GO:0030136]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; yolk [GO:0060417]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; hormone binding [GO:0042562]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; small molecule binding [GO:0036094]; thyroid hormone binding [GO:0070324]
d3espb__d1x7sa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3esqa__d4bkmc___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; D,D-heptose 1,7-bisphosphate phosphatase activity [GO:0034200]; magnesium ion binding [GO:0000287]; zinc ion binding [GO:0008270]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytoplasm [GO:0005737]; glycerol-1-phosphatase activity [GO:0000121]; glycerol-3-phosphatase activity [GO:0043136]; magnesium ion binding [GO:0000287]; nucleotide phosphatase activity, acting on free nucleotides [GO:0098519]; phosphatase activity [GO:0016791]; phosphoglycolate phosphatase activity [GO:0008967]; protein tyrosine phosphatase activity [GO:0004725]; dephosphorylation [GO:0016311]; glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721]; peptidyl-tyrosine dephosphorylation [GO:0035335]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dephosphorylation [GO:0016311]; glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721]; peptidyl-tyrosine dephosphorylation [GO:0035335]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	D,D-heptose 1,7-bisphosphate phosphatase activity [GO:0034200]; magnesium ion binding [GO:0000287]; zinc ion binding [GO:0008270]	glycerol-1-phosphatase activity [GO:0000121]; glycerol-3-phosphatase activity [GO:0043136]; magnesium ion binding [GO:0000287]; nucleotide phosphatase activity, acting on free nucleotides [GO:0098519]; phosphatase activity [GO:0016791]; phosphoglycolate phosphatase activity [GO:0008967]; protein tyrosine phosphatase activity [GO:0004725]
d3esta__d2fomb1__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3esuf1_d2nlja1__1				Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d3esuf1_d4j4pa3__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3esvf2_d1y18e1__1												
d3esvg1_d1etzh1__1		Metazoa		Chordata								
d3esvg2_d1aqdg1__1		Metazoa		Chordata		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]
d3esxa__d5ea2c1__1		Metazoa	Cyanobacteria	Chordata	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3eszb__d4xdgb___1		Metazoa	Cyanobacteria	Chordata	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d3et9f1_d2vlke1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3et9f1_d2yd1a1__1		Metazoa		Arthropoda		axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]		axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]		axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]		heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d3et9f2_d4f33c1__1												
d3etda2_d1k0uf1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]
d3etde1_d3k8za1__1	Metazoa		Chordata	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	glutamate dehydrogenase (NAD+) activity [GO:0004352]
d3etdf2_d1mgob2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d3etec2_d2x86b___1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]
d3eted1_d3k92a1__1	Metazoa		Chordata	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	glutamate dehydrogenase (NAD+) activity [GO:0004352]
d3etgd1_d2tmge2__1	Metazoa		Chordata	Thermotogae	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d3etgd1_d2yfgf1__1	Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	
d3etge1_d1bw9a2__1	Metazoa		Chordata	Actinobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d3etgf1_d1hwyb2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d3etha2_d3vpdb1__1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	'de novo' IMP biosynthetic process [GO:0006189]	cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytosol [GO:0005829]		5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]
d3ethb2_d5d8df1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d3etja3_d2v59b2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d3etjb1_d1kj9b1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]	cytosol [GO:0005829]	5-(carboxyamino)imidazole ribonucleotide synthase activity [GO:0034028]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d3etmb1_d5yolb___1				Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3etqa__d1rl3a2__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; molecular adaptor activity [GO:0060090]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; molecular adaptor activity [GO:0060090]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]
d3etra1_d1xlob___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3etrl1_d1fxic___1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3etrn2_d4us8a4__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3eu9b__d4a63l1__1	Metazoa	Metazoa	Chordata	Chordata	aggresome [GO:0016235]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle membrane [GO:0030659]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; presynaptic membrane [GO:0042734]; identical protein binding [GO:0042802]; magnesium ion transmembrane transporter activity [GO:0015095]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; lipoprotein transport [GO:0042953]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	lipoprotein transport [GO:0042953]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	aggresome [GO:0016235]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle membrane [GO:0030659]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; presynaptic membrane [GO:0042734]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; magnesium ion transmembrane transporter activity [GO:0015095]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3eub21_d3b2ga___1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3eub22_d4zohc2__1	Metazoa		Chordata	Crenarchaeota	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3eub42_d1n60b2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3euba2_d1jrpe1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3eubb1_d1n61f2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3eubc1_d1n62e1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3eubj1_d1i7ha___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; iron-sulfur cluster assembly [GO:0016226]	xanthine catabolic process [GO:0009115]	iron-sulfur cluster assembly [GO:0016226]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3eubj2_d1t3qa1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	oxidoreductase activity [GO:0016491]
d3eubk2_d1n61c1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3evea__d1hmya___1				Proteobacteria	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; negative regulation of RNA interference [GO:1900369]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; negative regulation of RNA interference [GO:1900369]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA restriction-modification system [GO:0009307]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d3evfa__d3e05d___1				Proteobacteria	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; negative regulation of RNA interference [GO:1900369]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	protein methyltransferase activity [GO:0008276]; cobalamin biosynthetic process [GO:0009236]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; negative regulation of RNA interference [GO:1900369]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cobalamin biosynthetic process [GO:0009236]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	protein methyltransferase activity [GO:0008276]
d3evha1_d1f1sa1__1				Firmicutes		extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d3evhb1_d1n7oa1__1				Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		cell wall [GO:0005618]; extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d3evhb1_d4f13a1__1				Proteobacteria		periplasmic space [GO:0042597]; lyase activity [GO:0016829]				periplasmic space [GO:0042597]		lyase activity [GO:0016829]
d3evka1_d2cdyc1__1			Crenarchaeota	Deinococcus-Thermus	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3evka2_d4gunl2__1		Fungi	Crenarchaeota	Ascomycota	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3evkb1_d1ar5a1__1			Crenarchaeota	Actinobacteria	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3evkb1_d3ak2b1__1			Crenarchaeota	Crenarchaeota	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3evkb2_d1ma1b2__1			Crenarchaeota	Euryarchaeota	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3evkb2_d4l2da2__1			Crenarchaeota	Proteobacteria	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3evkd2_d3ceib2__1			Crenarchaeota	Proteobacteria	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to iron ion [GO:0071281]		cellular response to iron ion [GO:0071281]		cytosol [GO:0005829]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3evma1_d3fcwf1__1					ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3evmb1_d3ztri___1				Aquificae	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3evwb1_d3fcwd1__1					ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ew4a1_d3evlb1__1												
d3ewda1_d1bf6a___1			Apicomplexa	Proteobacteria	deaminase activity [GO:0019239]; metal ion binding [GO:0046872]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]	hydrolase activity, acting on ester bonds [GO:0016788]; zinc ion binding [GO:0008270]; catabolic process [GO:0009056]	purine ribonucleoside monophosphate biosynthetic process [GO:0009168]	catabolic process [GO:0009056]			deaminase activity [GO:0019239]; metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; zinc ion binding [GO:0008270]
d3ewjb__d5ma7e___1	Metazoa		Chordata	Firmicutes	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]		actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3ewoa1_d5laua1__1				Firmicutes	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	nucleotide binding [GO:0000166]	induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]		cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]	nucleotide binding [GO:0000166]
d3ewqa__d3vfqa1__1		Metazoa		Chordata	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; protein ADP-ribosylase activity [GO:1990404]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; protein ADP-ribosylase activity [GO:1990404]
d3ewqa__d5cb5o___1				Proteobacteria	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]; negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]		cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]
d3ewta__d1gjyc___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]; calcium ion binding [GO:0005509]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]
d3ex8a2_d3f0qx___1			Firmicutes		5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]		riboflavin biosynthetic process [GO:0009231]				5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]	
d3ex8b1_d4hrwa___1			Firmicutes	Proteobacteria	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]	riboflavin biosynthetic process [GO:0009231]				5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]
d3ex8b1_d5cqka___1		Metazoa	Firmicutes	Chordata	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]	riboflavin biosynthetic process [GO:0009231]	cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]		cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3ex8c1_d2z3gc___1		Fungi	Firmicutes	Ascomycota	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	riboflavin biosynthetic process [GO:0009231]	response to antibiotic [GO:0046677]			5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d3ex8d1_d1mq0b___1		Metazoa	Firmicutes	Chordata	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytidine deaminase activity [GO:0004126]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; cell surface receptor signaling pathway [GO:0007166]; cytidine deamination [GO:0009972]; cytosine metabolic process [GO:0019858]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; neutrophil degranulation [GO:0043312]; protein homotetramerization [GO:0051289]; pyrimidine nucleoside salvage [GO:0043097]; pyrimidine-containing compound salvage [GO:0008655]	riboflavin biosynthetic process [GO:0009231]	cell surface receptor signaling pathway [GO:0007166]; cytidine deamination [GO:0009972]; cytosine metabolic process [GO:0019858]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; neutrophil degranulation [GO:0043312]; protein homotetramerization [GO:0051289]; pyrimidine-containing compound salvage [GO:0008655]; pyrimidine nucleoside salvage [GO:0043097]		cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; nucleoside binding [GO:0001882]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]
d3ex8d2_d4kaka___1		Metazoa	Firmicutes	Chordata	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	riboflavin biosynthetic process [GO:0009231]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3exba__d5twta___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3exea1_d5i5ga1__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d3exeb1_d1trka2__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	pentose-phosphate shunt [GO:0006098]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d3exec1_d3exgb1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d3exed1_d4k9pa1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	mandelate catabolic process [GO:0019596]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3exed2_d5vrbb3__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d3exeh2_d1trkb3__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	pentose-phosphate shunt [GO:0006098]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d3exeh2_d2beub2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]
d3exfb1_d1y9da3__1	Metazoa		Chordata	Firmicutes	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	magnesium ion binding [GO:0000287]; pyruvate oxidase activity [GO:0047112]; thiamine pyrophosphate binding [GO:0030976]
d3exfd2_d2r5nb3__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d3exfe1_d1w85g___1	Metazoa		Chordata	Firmicutes	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d3exff2_d1um9b2__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]
d3exfh1_d1x7xb1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]
d3exfh1_d2wvhf1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d3exfh2_d1keka3__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	cytoplasm [GO:0005737]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d3exg42_d1umbb2__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]
d3exg42_d5i51a3__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d3exg61_d3dvah1__1	Metazoa		Chordata	Firmicutes	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d3exgb2_d2c3ya3__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	cytoplasm [GO:0005737]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d3exgd2_d2r8ob3__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d3exgf1_d1jscb2__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3exgh2_d3dufb2__1	Metazoa		Chordata	Firmicutes	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d3exgj1_d2ji9b3__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	oxalate catabolic process [GO:0033611]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d3exgp2_d2ieab3__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	cytosol [GO:0005829]; membrane [GO:0016020]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]
d3exgr1_d2w93b3__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d3exgt2_d2c3pb3__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	cytoplasm [GO:0005737]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d3exgx2_d2ieaa3__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]; glycolytic process [GO:0006096]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	cytosol [GO:0005829]; membrane [GO:0016020]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; pyruvate dehydrogenase activity [GO:0004738]; thiamine pyrophosphate binding [GO:0030976]
d3exgz1_d4jucb1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	mandelate catabolic process [GO:0019596]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3exhb1_d2c3oa2__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	cytoplasm [GO:0005737]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d3exhb2_d1b0pa3__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]; electron transport chain [GO:0022900]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	cytoplasm [GO:0005737]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	4 iron, 4 sulfur cluster binding [GO:0051539]; iron ion binding [GO:0005506]; pyruvate synthase activity [GO:0019164]; thiamine pyrophosphate binding [GO:0030976]
d3exhd1_d1umcb1__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; metal ion binding [GO:0046872]
d3exhf1_d2g1ic3__1	Metazoa		Chordata		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]		pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	
d3exjb__d1gjib2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; central nervous system development [GO:0007417]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; chromosome organization [GO:0051276]; circadian behavior [GO:0048512]; circadian rhythm [GO:0007623]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; heart development [GO:0007507]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of mitophagy [GO:1901525]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron apoptotic process [GO:0043523]; regulation of thymocyte apoptotic process [GO:0070243]; regulation of tissue remodeling [GO:0034103]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to caffeine [GO:0031000]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to oxidative stress [GO:0006979]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; apoptotic DNA fragmentation [GO:0006309]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]	apoptotic process [GO:0006915]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; central nervous system development [GO:0007417]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; chromosome organization [GO:0051276]; circadian behavior [GO:0048512]; circadian rhythm [GO:0007623]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; heart development [GO:0007507]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of mitophagy [GO:1901525]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron apoptotic process [GO:0043523]; regulation of thymocyte apoptotic process [GO:0070243]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to caffeine [GO:0031000]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to oxidative stress [GO:0006979]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	apoptotic DNA fragmentation [GO:0006309]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]	cell [GO:0005623]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d3exua__d2wqzc___1		Metazoa	Firmicutes	Chordata	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]	xylan catabolic process [GO:0045493]	angiogenesis [GO:0001525]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cellular response to calcium ion [GO:0071277]; cerebellar granule cell differentiation [GO:0021707]; circadian rhythm [GO:0007623]; establishment of protein localization [GO:0045184]; gamma-aminobutyric acid receptor clustering [GO:0097112]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; guanylate kinase-associated protein clustering [GO:0097117]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of filopodium assembly [GO:0051490]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of presynaptic active zone assembly [GO:1905520]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; protein-containing complex assembly involved in synapse maturation [GO:0090126]; protein heterotetramerization [GO:0051290]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of AMPA receptor activity [GO:2000311]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; synaptic vesicle clustering [GO:0097091]		axonal growth cone [GO:0044295]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	endo-1,4-beta-xylanase activity [GO:0031176]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; signaling receptor binding [GO:0005102]; transmembrane signaling receptor activity [GO:0004888]
d3exva__d2oj6b1__1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	viral outer capsid [GO:0039624]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	viral outer capsid [GO:0039624]		
d3exwb__d2j2jf___1					host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]		
d3exwc__d2w9li___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3exya__d3euna___1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]			4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]
d3ey4a__d4bqra___1	Metazoa		Chordata	Actinobacteria	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d3eymc__d5t08a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3eyoc2_d2ok0l1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	metal ion binding [GO:0046872]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d3eyqc1_d2nyyd1__1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	negative regulation of neurotransmitter secretion [GO:0046929]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d3eyva2_d1i3vb1__1												
d3eyvb1_d1j1pl___1		Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3eyvh1_d1wtlb___1		Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d3eyvh1_d4ra0c1__1		Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; platelet alpha granule lumen [GO:0031093]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; phosphatidylserine binding [GO:0001786]; protein binding, bridging [GO:0030674]; protein tyrosine kinase activator activity [GO:0030296]; receptor ligand activity [GO:0048018]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; voltage-gated calcium channel activity [GO:0005245]; activation of protein kinase B activity [GO:0032148]; animal organ regeneration [GO:0031100]; apoptotic cell clearance [GO:0043277]; B cell chemotaxis [GO:0035754]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular protein metabolic process [GO:0044267]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to interferon-alpha [GO:0035457]; cellular response to starvation [GO:0009267]; cellular response to vitamin K [GO:0071307]; dendritic cell differentiation [GO:0097028]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; enzyme linked receptor protein signaling pathway [GO:0007167]; extracellular matrix assembly [GO:0085029]; fusion of virus membrane with host plasma membrane [GO:0019064]; hematopoietic stem cell migration to bone marrow [GO:0097241]; leukocyte migration [GO:0050900]; macrophage cytokine production [GO:0010934]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 secretion [GO:0050711]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of oligodendrocyte apoptotic process [GO:1900142]; negative regulation of renal albumin absorption [GO:2000533]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; neuron migration [GO:0001764]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerular filtration [GO:0003104]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of TOR signaling [GO:0032008]; post-translational protein modification [GO:0043687]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of growth [GO:0040008]; signal transduction [GO:0007165]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]		activation of protein kinase B activity [GO:0032148]; animal organ regeneration [GO:0031100]; apoptotic cell clearance [GO:0043277]; B cell chemotaxis [GO:0035754]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular protein metabolic process [GO:0044267]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to interferon-alpha [GO:0035457]; cellular response to starvation [GO:0009267]; cellular response to vitamin K [GO:0071307]; dendritic cell differentiation [GO:0097028]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; enzyme linked receptor protein signaling pathway [GO:0007167]; extracellular matrix assembly [GO:0085029]; fusion of virus membrane with host plasma membrane [GO:0019064]; hematopoietic stem cell migration to bone marrow [GO:0097241]; leukocyte migration [GO:0050900]; macrophage cytokine production [GO:0010934]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 secretion [GO:0050711]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of oligodendrocyte apoptotic process [GO:1900142]; negative regulation of renal albumin absorption [GO:2000533]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; neuron migration [GO:0001764]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerular filtration [GO:0003104]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of TOR signaling [GO:0032008]; post-translational protein modification [GO:0043687]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of growth [GO:0040008]; signal transduction [GO:0007165]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]		cell [GO:0005623]; cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; platelet alpha granule lumen [GO:0031093]		calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; phosphatidylserine binding [GO:0001786]; protein binding, bridging [GO:0030674]; protein tyrosine kinase activator activity [GO:0030296]; receptor ligand activity [GO:0048018]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor binding [GO:0005102]; voltage-gated calcium channel activity [GO:0005245]
d3eyyb__d3bpva___1			Actinobacteria	Euryarchaeota	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of secondary metabolite biosynthetic process [GO:1900376]	DNA-binding transcription factor activity [GO:0003700]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of secondary metabolite biosynthetic process [GO:1900376]				DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]	DNA-binding transcription factor activity [GO:0003700]
d3ezab__d3le3a___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]; enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	cytoplasm [GO:0005737]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; positive regulation of glycogen catabolic process [GO:0045819]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytosol [GO:0005829]; phosphoenolpyruvate-dependent sugar phosphotransferase complex [GO:0019197]	cytoplasm [GO:0005737]	enzyme activator activity [GO:0008047]; kinase activity [GO:0016301]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]	transferase activity [GO:0016740]
d3ezdb__d3le1a___1				Firmicutes		cytoplasm [GO:0005737]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]		phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]		cytoplasm [GO:0005737]		transferase activity [GO:0016740]
d3ezjb1_d2qr0k1__1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; type II protein secretion system complex [GO:0015627]; protein secretion by the type II secretion system [GO:0015628]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	protein secretion by the type II secretion system [GO:0015628]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell outer membrane [GO:0009279]; type II protein secretion system complex [GO:0015627]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ezjb1_d5kw9l2__1			Proteobacteria		cell outer membrane [GO:0009279]; type II protein secretion system complex [GO:0015627]; protein secretion by the type II secretion system [GO:0015628]	host cell cytoplasm [GO:0030430]; T=3 icosahedral viral capsid [GO:0039617]; identical protein binding [GO:0042802]	protein secretion by the type II secretion system [GO:0015628]		cell outer membrane [GO:0009279]; type II protein secretion system complex [GO:0015627]	host cell cytoplasm [GO:0030430]; T=3 icosahedral viral capsid [GO:0039617]		identical protein binding [GO:0042802]
d3ezjd1_d1u8oa1__1			Proteobacteria		cell outer membrane [GO:0009279]; type II protein secretion system complex [GO:0015627]; protein secretion by the type II secretion system [GO:0015628]		protein secretion by the type II secretion system [GO:0015628]		cell outer membrane [GO:0009279]; type II protein secretion system complex [GO:0015627]			
d3ezna__d4arva___1			Proteobacteria	Proteobacteria	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]				2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]	
d3eznb1_d1nt4b___1			Proteobacteria	Proteobacteria	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	outer membrane-bounded periplasmic space [GO:0030288]; 3-phytase activity [GO:0016158]; glucose-1-phosphatase activity [GO:0008877]; glucose catabolic process [GO:0006007]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glucose catabolic process [GO:0006007]		outer membrane-bounded periplasmic space [GO:0030288]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]	3-phytase activity [GO:0016158]; glucose-1-phosphatase activity [GO:0008877]
d3ezqb__d4rhwa___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d3ezqf__d5wvcc___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d3ezqh__d2a5yb2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	cell junction [GO:0030054]; endomembrane system [GO:0012505]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; organelle membrane [GO:0031090]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; presynapse [GO:0098793]; GTPase activator activity [GO:0005096]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; actin filament depolymerization [GO:0030042]; apoptotic process [GO:0006915]; apoptotic process involved in development [GO:1902742]; autophagy of mitochondrion [GO:0000422]; defense response to Gram-negative bacterium [GO:0050829]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of programmed cell death [GO:0043069]; positive regulation of brood size [GO:0090727]; positive regulation of embryonic development [GO:0040019]; positive regulation of fertilization [GO:1905516]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of oviposition [GO:1901046]; positive regulation of synapse pruning [GO:1905808]; protein processing [GO:0016485]; regulation of synapse organization [GO:0050807]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	actin filament depolymerization [GO:0030042]; apoptotic process [GO:0006915]; apoptotic process involved in development [GO:1902742]; autophagy of mitochondrion [GO:0000422]; defense response to Gram-negative bacterium [GO:0050829]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of programmed cell death [GO:0043069]; positive regulation of brood size [GO:0090727]; positive regulation of embryonic development [GO:0040019]; positive regulation of fertilization [GO:1905516]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of oviposition [GO:1901046]; positive regulation of synapse pruning [GO:1905808]; protein processing [GO:0016485]; regulation of synapse organization [GO:0050807]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	cell junction [GO:0030054]; endomembrane system [GO:0012505]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; organelle membrane [GO:0031090]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; presynapse [GO:0098793]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	GTPase activator activity [GO:0005096]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d3ezqj__d1c15a___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d3ezqk1_d1dgna___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	protein-containing complex [GO:0032991]; CARD domain binding [GO:0050700]; caspase binding [GO:0089720]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; inflammatory response [GO:0006954]; inhibition of cysteine-type endopeptidase activity [GO:0097340]; negative regulation of interleukin-1 beta secretion [GO:0050713]; negative regulation of protein binding [GO:0032091]; regulation of apoptotic process [GO:0042981]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	inflammatory response [GO:0006954]; inhibition of cysteine-type endopeptidase activity [GO:0097340]; negative regulation of interleukin-1 beta secretion [GO:0050713]; negative regulation of protein binding [GO:0032091]; regulation of apoptotic process [GO:0042981]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	protein-containing complex [GO:0032991]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	CARD domain binding [GO:0050700]; caspase binding [GO:0089720]; cysteine-type endopeptidase inhibitor activity [GO:0004869]
d3ezqm1_d2n83a___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endosome [GO:0005768]; extracellular region [GO:0005576]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; calmodulin binding [GO:0005516]; coreceptor activity [GO:0015026]; death receptor activity [GO:0005035]; nerve growth factor binding [GO:0048406]; neurotrophin binding [GO:0043121]; Rab GTPase binding [GO:0017137]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular glucose homeostasis [GO:0001678]; cellular response to amyloid-beta [GO:1904646]; circadian regulation of gene expression [GO:0032922]; glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of protein localization to nucleus [GO:1900182]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; Rho protein signal transduction [GO:0007266]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular glucose homeostasis [GO:0001678]; cellular response to amyloid-beta [GO:1904646]; circadian regulation of gene expression [GO:0032922]; glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of protein localization to nucleus [GO:1900182]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; Rho protein signal transduction [GO:0007266]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endosome [GO:0005768]; extracellular region [GO:0005576]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	amyloid-beta binding [GO:0001540]; calmodulin binding [GO:0005516]; coreceptor activity [GO:0015026]; death receptor activity [GO:0005035]; nerve growth factor binding [GO:0048406]; neurotrophin binding [GO:0043121]; Rab GTPase binding [GO:0017137]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]
d3ezqn__d2l6aa1__1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 secretion [GO:0050711]; negative regulation of interleukin-6 biosynthetic process [GO:0045409]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interleukin-18 biosynthetic process [GO:0045381]; signal transduction [GO:0007165]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 secretion [GO:0050711]; negative regulation of interleukin-6 biosynthetic process [GO:0045409]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interleukin-18 biosynthetic process [GO:0045381]; signal transduction [GO:0007165]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	cytoplasm [GO:0005737]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]
d3ezqo1_d4f44b___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated endocytic vesicle [GO:0045334]; coated vesicle [GO:0030135]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuronal cell body membrane [GO:0032809]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; amyloid-beta binding [GO:0001540]; calmodulin binding [GO:0005516]; coreceptor activity [GO:0015026]; death receptor activity [GO:0005035]; identical protein binding [GO:0042802]; nerve growth factor binding [GO:0048406]; neurotrophin binding [GO:0043121]; neurotrophin TRKA receptor binding [GO:0005168]; preprotein binding [GO:0070678]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; apoptotic process [GO:0006915]; cellular glucose homeostasis [GO:0001678]; cellular response to oxidative stress [GO:0034599]; circadian regulation of gene expression [GO:0032922]; glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; positive regulation of apoptotic process [GO:0043065]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of myelination [GO:0031643]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of cell death [GO:0010941]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to lipopolysaccharide [GO:0032496]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; skeletal muscle cell differentiation [GO:0035914]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	apoptotic process [GO:0006915]; cellular glucose homeostasis [GO:0001678]; cellular response to oxidative stress [GO:0034599]; circadian regulation of gene expression [GO:0032922]; glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; positive regulation of apoptotic process [GO:0043065]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of myelination [GO:0031643]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of cell death [GO:0010941]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to lipopolysaccharide [GO:0032496]; response to wounding [GO:0009611]; Rho protein signal transduction [GO:0007266]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; skeletal muscle cell differentiation [GO:0035914]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated endocytic vesicle [GO:0045334]; coated vesicle [GO:0030135]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuronal cell body membrane [GO:0032809]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	amyloid-beta binding [GO:0001540]; calmodulin binding [GO:0005516]; coreceptor activity [GO:0015026]; death receptor activity [GO:0005035]; identical protein binding [GO:0042802]; nerve growth factor binding [GO:0048406]; neurotrophin binding [GO:0043121]; neurotrophin TRKA receptor binding [GO:0005168]; preprotein binding [GO:0070678]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; Rab GTPase binding [GO:0017137]
d3ezqp__d4rhwe___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]; caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; behavioral response to cocaine [GO:0048148]; cell surface receptor signaling pathway [GO:0007166]; cellular response to mechanical stimulus [GO:0071260]; death-inducing signaling complex assembly [GO:0071550]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; kidney development [GO:0001822]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of apoptotic process [GO:0043065]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; response to morphine [GO:0043278]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; toll-like receptor 3 signaling pathway [GO:0034138]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	CD95 death-inducing signaling complex [GO:0031265]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ripoptosome [GO:0097342]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	caspase binding [GO:0089720]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; receptor serine/threonine kinase binding [GO:0033612]; tumor necrosis factor receptor binding [GO:0005164]; tumor necrosis factor receptor superfamily binding [GO:0032813]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d3ezwh2_d4h5ra2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	cytosol [GO:0005829]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3ezzb__d1fpzf___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; MAP kinase serine/threonine phosphatase activity [GO:1990439]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cell cycle arrest [GO:0007050]; cilium assembly [GO:0060271]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell population proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]	cell cycle arrest [GO:0007050]; cilium assembly [GO:0060271]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell population proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]	MAP kinase serine/threonine phosphatase activity [GO:1990439]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; protein tyrosine phosphatase activity [GO:0004725]	protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d3ezzb__d3u96a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; MAP kinase serine/threonine phosphatase activity [GO:1990439]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]	pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	extracellular region [GO:0005576]	MAP kinase serine/threonine phosphatase activity [GO:1990439]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d3ezzc__d2f71a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; MAP kinase serine/threonine phosphatase activity [GO:1990439]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	MAP kinase serine/threonine phosphatase activity [GO:1990439]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3ezzd__d4ri4a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; MAP kinase serine/threonine phosphatase activity [GO:1990439]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine phosphatase activity [GO:0004725]; sodium channel regulator activity [GO:0017080]; liver regeneration [GO:0097421]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of mitotic cell cycle [GO:0045930]; protein dephosphorylation [GO:0006470]; regulation of membrane depolarization during action potential [GO:0098902]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]	liver regeneration [GO:0097421]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of mitotic cell cycle [GO:0045930]; protein dephosphorylation [GO:0006470]; regulation of membrane depolarization during action potential [GO:0098902]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886]	MAP kinase serine/threonine phosphatase activity [GO:1990439]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; protein tyrosine phosphatase activity [GO:0004725]	ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine phosphatase activity [GO:0004725]; sodium channel regulator activity [GO:0017080]
d3f00a1_d1dqva1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; clathrin-coated vesicle membrane [GO:0030665]; clathrin-sculpted acetylcholine transport vesicle membrane [GO:0060201]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; clathrin-sculpted glutamate transport vesicle membrane [GO:0060203]; clathrin-sculpted monoamine transport vesicle membrane [GO:0070083]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; 1-phosphatidylinositol binding [GO:0005545]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; glutamate secretion [GO:0014047]; membrane organization [GO:0061024]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of exocytosis [GO:0017157]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	exocytic vesicle [GO:0070382]; integral component of synaptic membrane [GO:0099699]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; clathrin binding [GO:0030276]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; positive regulation of vesicle fusion [GO:0031340]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; response to calcium ion [GO:0051592]; synaptic vesicle exocytosis [GO:0016079]; vesicle-mediated transport [GO:0016192]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; glutamate secretion [GO:0014047]; membrane organization [GO:0061024]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of exocytosis [GO:0017157]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; positive regulation of vesicle fusion [GO:0031340]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; response to calcium ion [GO:0051592]; synaptic vesicle exocytosis [GO:0016079]; vesicle-mediated transport [GO:0016192]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; clathrin-coated vesicle membrane [GO:0030665]; clathrin-sculpted acetylcholine transport vesicle membrane [GO:0060201]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; clathrin-sculpted glutamate transport vesicle membrane [GO:0060203]; clathrin-sculpted monoamine transport vesicle membrane [GO:0070083]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]	exocytic vesicle [GO:0070382]; integral component of synaptic membrane [GO:0099699]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; synapse [GO:0045202]; transport vesicle membrane [GO:0030658]	1-phosphatidylinositol binding [GO:0005545]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; clathrin binding [GO:0030276]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]
d3f01a1_d1wfma1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; clathrin-coated vesicle membrane [GO:0030665]; clathrin-sculpted acetylcholine transport vesicle membrane [GO:0060201]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; clathrin-sculpted glutamate transport vesicle membrane [GO:0060203]; clathrin-sculpted monoamine transport vesicle membrane [GO:0070083]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; 1-phosphatidylinositol binding [GO:0005545]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; glutamate secretion [GO:0014047]; membrane organization [GO:0061024]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of exocytosis [GO:0017157]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	axon [GO:0030424]; exocytic vesicle [GO:0070382]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; clathrin binding [GO:0030276]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192]	brain development [GO:0007420]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; detection of calcium ion [GO:0005513]; fast, calcium ion-dependent exocytosis of neurotransmitter [GO:0098746]; glutamate secretion [GO:0014047]; membrane organization [GO:0061024]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903235]; positive regulation of dendrite extension [GO:1903861]; positive regulation of synaptic transmission [GO:0050806]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of exocytosis [GO:0017157]; regulation of regulated secretory pathway [GO:1903305]; regulation of synaptic transmission, glutamatergic [GO:0051966]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; synchronous neurotransmitter secretion [GO:0071911]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; vesicle-mediated transport [GO:0016192]	axon [GO:0030424]; cell junction [GO:0030054]; chromaffin granule membrane [GO:0042584]; clathrin-coated vesicle membrane [GO:0030665]; clathrin-sculpted acetylcholine transport vesicle membrane [GO:0060201]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; clathrin-sculpted glutamate transport vesicle membrane [GO:0060203]; clathrin-sculpted monoamine transport vesicle membrane [GO:0070083]; cytoplasm [GO:0005737]; dense core granule [GO:0031045]; excitatory synapse [GO:0060076]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of synaptic vesicle membrane [GO:0030285]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]	axon [GO:0030424]; exocytic vesicle [GO:0070382]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	1-phosphatidylinositol binding [GO:0005545]; calcium-dependent phospholipid binding [GO:0005544]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; calcium ion sensor activity [GO:0061891]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; identical protein binding [GO:0042802]; low-density lipoprotein particle receptor binding [GO:0050750]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; syntaxin binding [GO:0019905]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; clathrin binding [GO:0030276]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]
d3f03k__d1k02a___1		Fungi	Proteobacteria	Ascomycota	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]					FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]
d3f0bx__d3fl8e1__1				Firmicutes		dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d3f0ga__d1u43a___1			Proteobacteria	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d3f0sx__d3nz6x___1		Fungi		Ascomycota		dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3f0ux__d1dr4a___1		Metazoa		Chordata		mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d3f0vx__d3lg4b___1				Firmicutes		dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3f0xx__d3hj3b1__1												
d3f0yb__d3da0b2__1					viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]		
d3f0yc__d1uxbb___1					viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	viral capsid [GO:0019028]		metal ion binding [GO:0046872]
d3f0ye__d3u6xe2__1					viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]		
d3f12a1_d2dd8h2__1						host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]		endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]		host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d3f12a2_d1ktlc1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3f12a2_d3fzud1__1												
d3f12c2_d4pjce1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3f15a__d4hx3c1__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	serine-type endopeptidase inhibitor activity [GO:0004867]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	serine-type endopeptidase inhibitor activity [GO:0004867]
d3f18a__d830cb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d3f19a__d1qjja___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cortical granule [GO:0060473]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; aspartic-type peptidase activity [GO:0070001]; glutamic-type peptidase activity [GO:0070002]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]; cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cortical granule [GO:0060473]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	aspartic-type peptidase activity [GO:0070001]; glutamic-type peptidase activity [GO:0070002]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]
d3f1pb__d1t18a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]		DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d3f1ra__d3fjib1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparan sulfate proteoglycan binding [GO:0043395]; receptor-receptor interaction [GO:0090722]; signaling receptor binding [GO:0005102]; cell-cell signaling [GO:0007267]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inner ear receptor cell differentiation [GO:0060113]; MAPK cascade [GO:0000165]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dopaminergic neuron differentiation [GO:1904340]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of dopamine secretion [GO:0014059]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell-cell signaling [GO:0007267]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inner ear receptor cell differentiation [GO:0060113]; MAPK cascade [GO:0000165]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dopaminergic neuron differentiation [GO:1904340]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of dopamine secretion [GO:0014059]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	extracellular region [GO:0005576]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparan sulfate proteoglycan binding [GO:0043395]; receptor-receptor interaction [GO:0090722]; signaling receptor binding [GO:0005102]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3f1rb__d1ilta___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparan sulfate proteoglycan binding [GO:0043395]; receptor-receptor interaction [GO:0090722]; signaling receptor binding [GO:0005102]; cell-cell signaling [GO:0007267]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inner ear receptor cell differentiation [GO:0060113]; MAPK cascade [GO:0000165]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dopaminergic neuron differentiation [GO:1904340]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of dopamine secretion [GO:0014059]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; interleukin-1 type I receptor antagonist activity [GO:0045352]; interleukin-1 type II receptor antagonist activity [GO:0045353]; interleukin-1, type I receptor binding [GO:0005150]; interleukin-1, type II receptor binding [GO:0005151]; acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; interleukin-1-mediated signaling pathway [GO:0070498]; lipid metabolic process [GO:0006629]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; response to glucocorticoid [GO:0051384]	cell-cell signaling [GO:0007267]; fibroblast growth factor receptor signaling pathway [GO:0008543]; inner ear receptor cell differentiation [GO:0060113]; MAPK cascade [GO:0000165]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dopaminergic neuron differentiation [GO:1904340]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of dopamine secretion [GO:0014059]; signal transduction [GO:0007165]	acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; interleukin-1-mediated signaling pathway [GO:0070498]; lipid metabolic process [GO:0006629]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; response to glucocorticoid [GO:0051384]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparan sulfate proteoglycan binding [GO:0043395]; receptor-receptor interaction [GO:0090722]; signaling receptor binding [GO:0005102]	cytokine activity [GO:0005125]; interleukin-1, type II receptor binding [GO:0005151]; interleukin-1, type I receptor binding [GO:0005150]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; interleukin-1 type II receptor antagonist activity [GO:0045353]; interleukin-1 type I receptor antagonist activity [GO:0045352]
d3f1va2_d3v62e2__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]
d3f1va2_d5tupb1__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	integral component of membrane [GO:0016021]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; myosin binding [GO:0017022]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	integral component of membrane [GO:0016021]; nucleus [GO:0005634]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; myosin binding [GO:0017022]
d3f1vb1_d3tbla1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d3f1wa2_d3pwea3__1	Fungi		Ascomycota	Proteobacteria	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3f27d__d2crja1__1	Metazoa	Metazoa	Chordata	Chordata	nuclear transcription factor complex [GO:0044798]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; beta-catenin binding [GO:0008013]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; angiogenesis [GO:0001525]; cardiac cell fate determination [GO:0060913]; cardiogenic plate morphogenesis [GO:0003142]; cell differentiation [GO:0030154]; cell migration involved in gastrulation [GO:0042074]; cellular response to leukemia inhibitory factor [GO:1990830]; common bile duct development [GO:0061009]; embryonic foregut morphogenesis [GO:0048617]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; embryonic organ development [GO:0048568]; endocardial cell differentiation [GO:0060956]; endocardium formation [GO:0060214]; endoderm development [GO:0007492]; endoderm formation [GO:0001706]; endodermal cell fate determination [GO:0007493]; endodermal digestive tract morphogenesis [GO:0061031]; gall bladder development [GO:0061010]; gastrulation [GO:0007369]; heart looping [GO:0001947]; inner cell mass cellular morphogenesis [GO:0001828]; metanephros development [GO:0001656]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of Wnt signaling pathway [GO:0030178]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; outflow tract morphogenesis [GO:0003151]; positive regulation of cell differentiation [GO:0045597]; positive regulation of gene expression [GO:0010628]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; regulation of cardiac cell fate specification [GO:2000043]; regulation of cell differentiation [GO:0045595]; regulation of embryonic development [GO:0045995]; regulation of stem cell division [GO:2000035]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification [GO:0060807]; regulation of transcription, DNA-templated [GO:0006355]; rostrocaudal neural tube patterning [GO:0021903]; signal transduction involved in regulation of gene expression [GO:0023019]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]; stem cell fate specification [GO:0048866]; ureter development [GO:0072189]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055]	BRCA2-BRAF35 complex [GO:0002111]; chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; four-way junction DNA binding [GO:0000400]; protein heterodimerization activity [GO:0046982]; cell cycle [GO:0007049]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of protein sumoylation [GO:0033234]; positive regulation of neuron differentiation [GO:0045666]; regulation of transcription, DNA-templated [GO:0006355]; skeletal muscle cell differentiation [GO:0035914]	angiogenesis [GO:0001525]; cardiac cell fate determination [GO:0060913]; cardiogenic plate morphogenesis [GO:0003142]; cell differentiation [GO:0030154]; cell migration involved in gastrulation [GO:0042074]; cellular response to leukemia inhibitory factor [GO:1990830]; common bile duct development [GO:0061009]; embryonic foregut morphogenesis [GO:0048617]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; embryonic organ development [GO:0048568]; endocardial cell differentiation [GO:0060956]; endocardium formation [GO:0060214]; endodermal cell fate determination [GO:0007493]; endodermal digestive tract morphogenesis [GO:0061031]; endoderm development [GO:0007492]; endoderm formation [GO:0001706]; gall bladder development [GO:0061010]; gastrulation [GO:0007369]; heart looping [GO:0001947]; inner cell mass cellular morphogenesis [GO:0001828]; metanephros development [GO:0001656]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of Wnt signaling pathway [GO:0030178]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; outflow tract morphogenesis [GO:0003151]; positive regulation of cell differentiation [GO:0045597]; positive regulation of gene expression [GO:0010628]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; regulation of cardiac cell fate specification [GO:2000043]; regulation of cell differentiation [GO:0045595]; regulation of embryonic development [GO:0045995]; regulation of stem cell division [GO:2000035]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification [GO:0060807]; rostrocaudal neural tube patterning [GO:0021903]; signal transduction involved in regulation of gene expression [GO:0023019]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]; stem cell fate specification [GO:0048866]; ureter development [GO:0072189]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055]	cell cycle [GO:0007049]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of protein sumoylation [GO:0033234]; positive regulation of neuron differentiation [GO:0045666]; regulation of transcription, DNA-templated [GO:0006355]; skeletal muscle cell differentiation [GO:0035914]	nuclear transcription factor complex [GO:0044798]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	BRCA2-BRAF35 complex [GO:0002111]; chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	beta-catenin binding [GO:0008013]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; four-way junction DNA binding [GO:0000400]; protein heterodimerization activity [GO:0046982]
d3f2ma1_d3qnab___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	queuosine biosynthetic process [GO:0008616]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d3f3ha__d1osya___1	Fungi	Fungi	Basidiomycota	Basidiomycota	carbohydrate binding [GO:0030246]; regulation of immune system process [GO:0002682]	carbohydrate binding [GO:0030246]; regulation of immune system process [GO:0002682]	regulation of immune system process [GO:0002682]	regulation of immune system process [GO:0002682]			carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d3f47a1_d5iflg___1			Euryarchaeota	Proteobacteria	N5,N10-methenyltetrahydromethanopterin hydrogenase activity [GO:0047068]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	fatty acid biosynthetic process [GO:0006633]			N5,N10-methenyltetrahydromethanopterin hydrogenase activity [GO:0047068]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d3f4fa__d1ogha___1	Fungi		Ascomycota	Euryarchaeota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d3f4fb__d1dutb___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d3f4na__d5dlcc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	cytoplasm [GO:0005737]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	pyridoxine 5'-phosphate synthase activity [GO:0033856]	pyridoxine 5'-phosphate synthase activity [GO:0033856]
d3f4nd__d3gk0b___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	cytoplasm [GO:0005737]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	pyridoxine 5'-phosphate synthase activity [GO:0033856]	pyridoxine 5'-phosphate synthase activity [GO:0033856]
d3f4nf__d3gk0g___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	cytoplasm [GO:0005737]; pyridoxine 5'-phosphate synthase activity [GO:0033856]; pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	pyridoxine biosynthetic process [GO:0008615]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	pyridoxine 5'-phosphate synthase activity [GO:0033856]	pyridoxine 5'-phosphate synthase activity [GO:0033856]
d3f4vb__d2xvpb1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3f4wa__d5lnra___1		Viridiplantae	Proteobacteria	Streptophyta	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; hexulose-6-phosphate synthase activity [GO:0043801]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]; amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]		cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; hexulose-6-phosphate synthase activity [GO:0043801]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3f4wb__d3femf___1		Fungi	Proteobacteria	Ascomycota	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; hexulose-6-phosphate synthase activity [GO:0043801]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]		glutaminase complex [GO:1903600]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; hexulose-6-phosphate synthase activity [GO:0043801]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3f4xa__d5jnac___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	anchored component of external side of plasma membrane [GO:0031362]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell surface [GO:0009986]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	anchored component of external side of plasma membrane [GO:0031362]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell surface [GO:0009986]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3f51b1_d3g5ge___1			Actinobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; positive regulation of transcription, DNA-templated [GO:0045893]	DNA binding [GO:0003677]	positive regulation of transcription, DNA-templated [GO:0045893]		protein-DNA complex [GO:0032993]		DNA-binding transcription activator activity [GO:0001216]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding [GO:0003677]
d3f55a__d1uasa2__1		Viridiplantae		Streptophyta		apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; raffinose alpha-galactosidase activity [GO:0052692]; carbohydrate metabolic process [GO:0005975]; leaf morphogenesis [GO:0009965]; positive regulation of flower development [GO:0009911]; response to fungus [GO:0009620]		carbohydrate metabolic process [GO:0005975]; leaf morphogenesis [GO:0009965]; positive regulation of flower development [GO:0009911]; response to fungus [GO:0009620]		apoplast [GO:0048046]; plant-type cell wall [GO:0009505]		raffinose alpha-galactosidase activity [GO:0052692]
d3f55a__d2bfga2__1				Firmicutes		xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]				xylan 1,4-beta-xylosidase activity [GO:0009044]
d3f55d__d2gk1.c__1		Metazoa		Chordata		acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]		astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]		acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]		acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d3f58l1_d3qdje2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3f5ia__d4oozb1__1		Metazoa		Arthropoda		mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metabolic process [GO:0008152]		metabolic process [GO:0008152]				mannan endo-1,4-beta-mannosidase activity [GO:0016985]
d3f5ib__d3gxda2__1		Metazoa		Chordata		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d3f5jb__d3mmuh___1	Viridiplantae		Streptophyta	Thermotogae	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3f5ka__d1i1xa___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	endo-1,4-beta-xylanase activity [GO:0031176]
d3f5ka__d4jhoa1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3f5ob__d1vh9a1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]; acyl-CoA hydrolase activity [GO:0047617]; acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; thiolester hydrolase activity [GO:0016790]; enterobactin biosynthetic process [GO:0009239]	acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]	enterobactin biosynthetic process [GO:0009239]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]	cytosol [GO:0005829]	acyl-CoA hydrolase activity [GO:0047617]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; thiolester hydrolase activity [GO:0016790]
d3f5ob__d5eo4a___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]; acyl-CoA hydrolase activity [GO:0047617]; acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]		acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]		acyl-CoA hydrolase activity [GO:0047617]	
d3f5oe__d2v1of___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]; acyl-CoA hydrolase activity [GO:0047617]; acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; fatty-acyl-CoA binding [GO:0000062]; identical protein binding [GO:0042802]; long-chain fatty acyl-CoA binding [GO:0036042]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290]; protein homodimerization activity [GO:0042803]; acyl-CoA metabolic process [GO:0006637]; coenzyme A biosynthetic process [GO:0015937]; fatty acid catabolic process [GO:0009062]; long-chain fatty-acyl-CoA catabolic process [GO:0036116]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; palmitic acid biosynthetic process [GO:1900535]	acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]	acyl-CoA metabolic process [GO:0006637]; coenzyme A biosynthetic process [GO:0015937]; fatty acid catabolic process [GO:0009062]; long-chain fatty-acyl-CoA catabolic process [GO:0036116]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; palmitic acid biosynthetic process [GO:1900535]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]	acyl-CoA hydrolase activity [GO:0047617]	acyl-CoA hydrolase activity [GO:0047617]; carboxylic ester hydrolase activity [GO:0052689]; fatty-acyl-CoA binding [GO:0000062]; identical protein binding [GO:0042802]; long-chain fatty acyl-CoA binding [GO:0036042]; myristoyl-CoA hydrolase activity [GO:0102991]; palmitoyl-CoA hydrolase activity [GO:0016290]; protein homodimerization activity [GO:0042803]
d3f5xb1_d4bcgb1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3f63b2_d4pngb2__1	Metazoa	Metazoa	Arthropoda	Arthropoda	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]		glutathione metabolic process [GO:0006749]		cytoplasm [GO:0005737]	transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]
d3f6ex1_d4judx3__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	mandelate catabolic process [GO:0019596]	mandelate catabolic process [GO:0019596]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3f6ex2_d5dx6a2__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; butanediol metabolic process [GO:0034077]	mandelate catabolic process [GO:0019596]	butanediol metabolic process [GO:0034077]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3f6ex3_d2ihvb3__1			Proteobacteria	Actinobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]	mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; N2-(2-carboxyethyl)arginine synthase activity [GO:0033848]; thiamine pyrophosphate binding [GO:0030976]
d3f6fa2_d3tgzb2__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	glutathione metabolic process [GO:0006749]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]
d3f6pa__d1bdja___1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d3f6pa__d2gkga___1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]	regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	
d3f6qa__d1g3nf___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cell-cell junction [GO:0005911]; costamere [GO:0043034]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; stress fiber [GO:0001725]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; integrin binding [GO:0005178]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; SH3 domain binding [GO:0017124]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell junction assembly [GO:0034329]; cell population proliferation [GO:0008283]; cell-matrix adhesion [GO:0007160]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; fibroblast migration [GO:0010761]; integrin-mediated signaling pathway [GO:0007229]; myelin assembly [GO:0032288]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; outflow tract morphogenesis [GO:0003151]; peptidyl-serine phosphorylation [GO:0018105]; platelet aggregation [GO:0070527]; positive regulation of axon extension [GO:0045773]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of signal transduction [GO:0009967]; positive regulation of transcription, DNA-templated [GO:0045893]; protein heterooligomerization [GO:0051291]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; substrate adhesion-dependent cell spreading [GO:0034446]; supramolecular fiber organization [GO:0097435]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]; astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	branching involved in ureteric bud morphogenesis [GO:0001658]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell population proliferation [GO:0008283]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; fibroblast migration [GO:0010761]; integrin-mediated signaling pathway [GO:0007229]; myelin assembly [GO:0032288]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; outflow tract morphogenesis [GO:0003151]; peptidyl-serine phosphorylation [GO:0018105]; platelet aggregation [GO:0070527]; positive regulation of axon extension [GO:0045773]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of signal transduction [GO:0009967]; positive regulation of transcription, DNA-templated [GO:0045893]; protein heterooligomerization [GO:0051291]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; substrate adhesion-dependent cell spreading [GO:0034446]; supramolecular fiber organization [GO:0097435]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	cell-cell junction [GO:0005911]; cell junction [GO:0030054]; costamere [GO:0043034]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; stress fiber [GO:0001725]; terminal bouton [GO:0043195]	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	ATP binding [GO:0005524]; integrin binding [GO:0005178]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; SH3 domain binding [GO:0017124]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]
d3f6rc__d1wswa___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3f6sa__d5a4kb___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3f6se__d5fuqa___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3f6sf__d4zvma___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d3f6sh__d1c7eb___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3f6sh__d3ojwa1__1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]		carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d3f6zc__d1l60a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3f7jb__d1vbja1__1			Firmicutes		methylglyoxal reductase (NADPH-dependent) activity [GO:0043892]	cytoplasm [GO:0005737]; aldo-keto reductase (NADP) activity [GO:0004033]; D-arabinose 1-dehydrogenase [NAD(P)+] activity [GO:0045290]; nucleotide binding [GO:0000166]; D-arabinose catabolic process [GO:0019571]; prostaglandin biosynthetic process [GO:0001516]		D-arabinose catabolic process [GO:0019571]; prostaglandin biosynthetic process [GO:0001516]		cytoplasm [GO:0005737]	methylglyoxal reductase (NADPH-dependent) activity [GO:0043892]	aldo-keto reductase (NADP) activity [GO:0004033]; D-arabinose 1-dehydrogenase [NAD(P)+] activity [GO:0045290]; nucleotide binding [GO:0000166]
d3f7ma__d1nlua___1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]	periplasmic space [GO:0042597]	serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3f7na__d3nhzb___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; growth of symbiont in host [GO:0044117]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	growth of symbiont in host [GO:0044117]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]	cytosol [GO:0005829]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; protein-DNA complex [GO:0032993]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3f7pa1_d2d89a1__1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	cytosol [GO:0005829]; endosome [GO:0005768]; filamentous actin [GO:0031941]; microtubule organizing center [GO:0005815]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; protein transport [GO:0015031]	hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; protein transport [GO:0015031]	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	cytosol [GO:0005829]; endosome [GO:0005768]; filamentous actin [GO:0031941]; microtubule organizing center [GO:0005815]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]	
d3f7pc1_d5m5ec2__1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; cytokine activity [GO:0005125]; glycosphingolipid binding [GO:0043208]; growth factor activity [GO:0008083]; interleukin-2 receptor binding [GO:0005134]; kappa-type opioid receptor binding [GO:0031851]; kinase activator activity [GO:0019209]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; immune response [GO:0006955]; interleukin-2-mediated signaling pathway [GO:0038110]; leukocyte activation involved in immune response [GO:0002366]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of heart contraction [GO:0045822]; negative regulation of inflammatory response [GO:0050728]; negative regulation of lymphocyte proliferation [GO:0050672]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; response to ethanol [GO:0045471]; T cell differentiation [GO:0030217]	hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; immune response [GO:0006955]; interleukin-2-mediated signaling pathway [GO:0038110]; leukocyte activation involved in immune response [GO:0002366]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of heart contraction [GO:0045822]; negative regulation of inflammatory response [GO:0050728]; negative regulation of lymphocyte proliferation [GO:0050672]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; response to ethanol [GO:0045471]; T cell differentiation [GO:0030217]	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]	carbohydrate binding [GO:0030246]; cytokine activity [GO:0005125]; glycosphingolipid binding [GO:0043208]; growth factor activity [GO:0008083]; interleukin-2 receptor binding [GO:0005134]; kappa-type opioid receptor binding [GO:0031851]; kinase activator activity [GO:0019209]
d3f7pd1_d1x3da1__1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; vesicle membrane [GO:0012506]; RNA binding [GO:0003723]; cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286]	hemidesmosome assembly [GO:0031581]; intermediate filament cytoskeleton organization [GO:0045104]; wound healing [GO:0042060]	cell-cell adhesion [GO:0098609]; fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; spermatid development [GO:0007286]	brush border [GO:0005903]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; hemidesmosome [GO:0030056]; intermediate filament cytoskeleton [GO:0045111]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]	acrosomal vesicle [GO:0001669]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; vesicle membrane [GO:0012506]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]	RNA binding [GO:0003723]
d3f80a__d2cevb___1	Metazoa		Chordata	Firmicutes	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]
d3f81a__d4quna1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; immunological synapse [GO:0001772]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cytoskeletal protein binding [GO:0008092]; MAP kinase phosphatase activity [GO:0033549]; phosphatase activity [GO:0016791]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; receptor tyrosine kinase binding [GO:0030971]; cellular response to epidermal growth factor stimulus [GO:0071364]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of focal adhesion assembly [GO:0051893]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine phosphatase activity [GO:0004725]; sodium channel regulator activity [GO:0017080]; liver regeneration [GO:0097421]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of mitotic cell cycle [GO:0045930]; protein dephosphorylation [GO:0006470]; regulation of membrane depolarization during action potential [GO:0098902]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	cellular response to epidermal growth factor stimulus [GO:0071364]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of cell migration [GO:0030336]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of focal adhesion assembly [GO:0051893]	liver regeneration [GO:0097421]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of mitotic cell cycle [GO:0045930]; protein dephosphorylation [GO:0006470]; regulation of membrane depolarization during action potential [GO:0098902]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	cytosol [GO:0005829]; immunological synapse [GO:0001772]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886]	cytoskeletal protein binding [GO:0008092]; MAP kinase phosphatase activity [GO:0033549]; phosphatase activity [GO:0016791]; protein kinase binding [GO:0019901]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]	ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine phosphatase activity [GO:0004725]; sodium channel regulator activity [GO:0017080]
d3f8aa__d4lzva___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]
d3f8bb__d4a2ub2__1			Firmicutes	Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]		negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3f8la__d1xlra___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cytosol [GO:0005829]; chorismate lyase activity [GO:0008813]; pyruvate biosynthetic process [GO:0042866]; ubiquinone biosynthetic process [GO:0006744]		pyruvate biosynthetic process [GO:0042866]; ubiquinone biosynthetic process [GO:0006744]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	chorismate lyase activity [GO:0008813]
d3f8la__d4zska1__1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]		negative regulation of transcription, DNA-templated [GO:0045892]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3f8lc__d2p19b___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]			cytoplasm [GO:0005737]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3f8sb2_d4bata___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	hydrolase activity [GO:0016787]
d3f8va__d1p5cd___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3f8va__d3lzta___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3f8ya__d3eela1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d3f8za__d4elfa1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d3f90b__d2ohja2__1			Proteobacteria	Euryarchaeota	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d3f90e__d5emna1__1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d3f90f__d2q62f___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]		oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]			electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]
d3f99a__d1onza___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	pathogenesis [GO:0009405]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	extracellular region [GO:0005576]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3f9aa__d1q6pa1__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	pathogenesis [GO:0009405]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	extracellular region [GO:0005576]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3f9da__d3stka1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]
d3f9da__d4orsa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d3f9fa__d1sqoa___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]
d3f9fb__d3f9ea___1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3f9ha__d3rxia___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3f9ha__d3zv8a1__1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3f9oa__d5k4na___1			Proteobacteria		periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	
d3f9oa__d5le1a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d3f9ra1_d1wr8a___1				Euryarchaeota	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycosome [GO:0020015]; nucleoplasm [GO:0005654]; metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]; GDP-mannose biosynthetic process [GO:0009298]; mannose biosynthetic process [GO:0019307]; mannose metabolic process [GO:0006013]; protein N-linked glycosylation [GO:0006487]; protein targeting to ER [GO:0045047]	magnesium ion binding [GO:0000287]; phosphoglycolate phosphatase activity [GO:0008967]; carbohydrate metabolic process [GO:0005975]	GDP-mannose biosynthetic process [GO:0009298]; mannose biosynthetic process [GO:0019307]; mannose metabolic process [GO:0006013]; protein N-linked glycosylation [GO:0006487]; protein targeting to ER [GO:0045047]	carbohydrate metabolic process [GO:0005975]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycosome [GO:0020015]; nucleoplasm [GO:0005654]		metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]	magnesium ion binding [GO:0000287]; phosphoglycolate phosphatase activity [GO:0008967]
d3f9ra1_d3qu4f___1				Bacteroidetes	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycosome [GO:0020015]; nucleoplasm [GO:0005654]; metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]; GDP-mannose biosynthetic process [GO:0009298]; mannose biosynthetic process [GO:0019307]; mannose metabolic process [GO:0006013]; protein N-linked glycosylation [GO:0006487]; protein targeting to ER [GO:0045047]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	GDP-mannose biosynthetic process [GO:0009298]; mannose biosynthetic process [GO:0019307]; mannose metabolic process [GO:0006013]; protein N-linked glycosylation [GO:0006487]; protein targeting to ER [GO:0045047]		ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycosome [GO:0020015]; nucleoplasm [GO:0005654]		metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]
d3fa0a__d4i7ob1__1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3fa0a__d4ml7a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3fa3a__d1f8ib___1	Fungi		Ascomycota	Actinobacteria	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]; zymogen binding [GO:0035375]; cellular response to hypoxia [GO:0071456]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; maintenance of symbiont tolerance to host environment [GO:0075141]; pathogenesis [GO:0009405]; response to acetate [GO:0010034]; response to acidic pH [GO:0010447]; response to fatty acid [GO:0070542]; response to host immune response [GO:0052572]; tricarboxylic acid cycle [GO:0006099]		cellular response to hypoxia [GO:0071456]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; maintenance of symbiont tolerance to host environment [GO:0075141]; pathogenesis [GO:0009405]; response to acetate [GO:0010034]; response to acidic pH [GO:0010447]; response to fatty acid [GO:0070542]; response to host immune response [GO:0052572]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]; zymogen binding [GO:0035375]
d3fa3e__d2x0sa1__1	Fungi		Ascomycota		hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	glycosome [GO:0020015]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]; phosphorylation [GO:0016310]; pyruvate metabolic process [GO:0006090]		phosphorylation [GO:0016310]; pyruvate metabolic process [GO:0006090]		glycosome [GO:0020015]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; pyruvate, phosphate dikinase activity [GO:0050242]
d3fa3k__d1f8mb___1	Fungi		Ascomycota	Actinobacteria	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]; zymogen binding [GO:0035375]; cellular response to hypoxia [GO:0071456]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; maintenance of symbiont tolerance to host environment [GO:0075141]; pathogenesis [GO:0009405]; response to acetate [GO:0010034]; response to acidic pH [GO:0010447]; response to fatty acid [GO:0070542]; response to host immune response [GO:0052572]; tricarboxylic acid cycle [GO:0006099]		cellular response to hypoxia [GO:0071456]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; maintenance of symbiont tolerance to host environment [GO:0075141]; pathogenesis [GO:0009405]; response to acetate [GO:0010034]; response to acidic pH [GO:0010447]; response to fatty acid [GO:0070542]; response to host immune response [GO:0052572]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	isocitrate lyase activity [GO:0004451]; metal ion binding [GO:0046872]; methylisocitrate lyase activity [GO:0046421]; zymogen binding [GO:0035375]
d3fa6a__d1znda___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]
d3fa6a__d5hz9a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]
d3fa6b__d3zq3d___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	small molecule binding [GO:0036094]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	small molecule binding [GO:0036094]
d3fa6b__d4ycha___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3fa7a__d4os3b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d3fa8b__d1kt5a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	extracellular space [GO:0005615]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	extracellular space [GO:0005615]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]
d3fa9a__d5bvqa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; linoleic acid binding [GO:0070539]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; stearic acid binding [GO:0070540]; cellular response to linoleic acid [GO:0071399]; long-chain fatty acid transport [GO:0015909]; regulation of inflammatory response [GO:0050727]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cellular response to linoleic acid [GO:0071399]; long-chain fatty acid transport [GO:0015909]; regulation of inflammatory response [GO:0050727]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	linoleic acid binding [GO:0070539]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; stearic acid binding [GO:0070540]
d3fada__d2zq4a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3faha1_d1kfyb2__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d3faha3_d1jroh1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3fatc1_d2xxxa___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of synapse structure or activity [GO:0050803]; response to fungicide [GO:0060992]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of synapse structure or activity [GO:0050803]; response to fungicide [GO:0060992]; synaptic transmission, glutamatergic [GO:0035249]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; terminal bouton [GO:0043195]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d3favb__d1wa8a1__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; host cell surface binding [GO:0046812]; protein homodimerization activity [GO:0042803]; modulation by symbiont of host signal transduction pathway [GO:0052027]; negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein secretion by the type VII secretion system [GO:0044315]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; host cell surface binding [GO:0046812]; protein homodimerization activity [GO:0042803]; modulation by symbiont of host signal transduction pathway [GO:0052027]; negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein secretion by the type VII secretion system [GO:0044315]	modulation by symbiont of host signal transduction pathway [GO:0052027]; negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein secretion by the type VII secretion system [GO:0044315]	modulation by symbiont of host signal transduction pathway [GO:0052027]; negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein secretion by the type VII secretion system [GO:0044315]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	host cell surface binding [GO:0046812]; protein homodimerization activity [GO:0042803]	host cell surface binding [GO:0046812]; protein homodimerization activity [GO:0042803]
d3fb0a__d2wo9b___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3fb3b1_d1yrec___1				Proteobacteria	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; glycosome [GO:0020015]; Golgi apparatus [GO:0005794]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]; N-acetylglucosamine metabolic process [GO:0006044]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	N-acetyltransferase activity [GO:0008080]	N-acetylglucosamine metabolic process [GO:0006044]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; glycosome [GO:0020015]; Golgi apparatus [GO:0005794]		glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]	N-acetyltransferase activity [GO:0008080]
d3fb5a2_d1cfsb2__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	voltage-gated potassium channel complex [GO:0008076]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3fb6b2_d1g9nc1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3fbbc1_d5v6dp___1				Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3fbbd1_d1kdnc___1					ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3fbbe1_d6ay1c___1				Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3fbcc1_d2dy9a___1				Euryarchaeota	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3fbcf1_d5iolk1__1		Metazoa		Platyhelminthes	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	nucleoside diphosphate kinase activity [GO:0004550]
d3fbea1_d3ztrk___1				Aquificae	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3fbec1_d4uofa___1		Metazoa		Arthropoda	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3fbed1_d4di6f1__1				Spirochaetes	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3fbfc1_d4fkya___1					ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; posttranscriptional regulation of gene expression [GO:0010608]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; posttranscriptional regulation of gene expression [GO:0010608]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3fbwa1_d1be0a___1			Actinobacteria	Proteobacteria	haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	response to toxic substance [GO:0009636]	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]			haloalkane dehalogenase activity [GO:0018786]	haloalkane dehalogenase activity [GO:0018786]
d3fc4a1_d1e6eb___1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]		cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]
d3fc9c1_d1bhna___1		Metazoa		Chordata	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; nervous system development [GO:0007399]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; nervous system development [GO:0007399]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3fc9e1_d5u2ic1__1				Heterolobosea	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3fcjc2_d3d9fd2__1	Fungi	Fungi	Ascomycota	Ascomycota	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]			FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d3fcjd2_d1t9gd1__1	Fungi	Metazoa	Ascomycota	Chordata	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	electron transfer activity [GO:0009055]
d3fckb1_d4wrya___1	Metazoa		Chordata	Actinobacteria	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d3fcqa__d3nqyb___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3fctb1_d1dn0c1__1		Metazoa		Chordata								
d3fctb2_d2bx5a___1		Metazoa		Chordata								
d3fctc2_d1cbvl1__1		Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d3fctd1_d3idna1__1												
d3fctd2_d1a6vi___1		Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		
d3fcwc1_d4f4ab___1					ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; posttranscriptional regulation of gene expression [GO:0010608]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; posttranscriptional regulation of gene expression [GO:0010608]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3fcwd1_d4di6d1__1				Spirochaetes	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3fcwe1_d3bbba___1		Metazoa		Chordata	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]		cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]
d3fcwf1_d4di6b1__1				Spirochaetes	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3fcyc__d2ajdc2__1		Metazoa	Firmicutes	Chordata	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3fd4b__d1yu1a2__1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; carbohydrate binding [GO:0030246]; viral process [GO:0016032]	virus tail, fiber [GO:0098024]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	viral process [GO:0016032]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; viral entry into host cell [GO:0046718]; viral tropism switching [GO:0098678]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	virus tail, fiber [GO:0098024]	carbohydrate binding [GO:0030246]	
d3fdua1_d1x0uc1__1				Crenarchaeota		acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; propionyl-CoA carboxylase activity [GO:0004658]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		acetyl-CoA carboxylase complex [GO:0009317]		acetyl-CoA carboxylase activity [GO:0003989]; propionyl-CoA carboxylase activity [GO:0004658]
d3fdwa__d2ki6a___1	Metazoa	Metazoa	Chordata	Chordata	endosome [GO:0005768]; exocytic vesicle [GO:0070382]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; transport vesicle membrane [GO:0030658]; metal ion binding [GO:0046872]; neurexin family protein binding [GO:0042043]; phospholipid binding [GO:0005543]; Rab GTPase binding [GO:0017137]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; multivesicular body sorting pathway [GO:0071985]; negative regulation of insulin secretion [GO:0046676]; plasma membrane repair [GO:0001778]; platelet degranulation [GO:0002576]; positive regulation of exocytosis [GO:0045921]; positive regulation of protein secretion [GO:0050714]; regulation of plasma membrane repair [GO:1905684]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; multivesicular body sorting pathway [GO:0071985]; negative regulation of insulin secretion [GO:0046676]; plasma membrane repair [GO:0001778]; platelet degranulation [GO:0002576]; positive regulation of exocytosis [GO:0045921]; positive regulation of protein secretion [GO:0050714]; regulation of plasma membrane repair [GO:1905684]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	endosome [GO:0005768]; exocytic vesicle [GO:0070382]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; transport vesicle membrane [GO:0030658]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	metal ion binding [GO:0046872]; neurexin family protein binding [GO:0042043]; phospholipid binding [GO:0005543]; Rab GTPase binding [GO:0017137]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3fdwb__d6ankb1__1	Metazoa	Metazoa	Chordata	Chordata	endosome [GO:0005768]; exocytic vesicle [GO:0070382]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; transport vesicle membrane [GO:0030658]; metal ion binding [GO:0046872]; neurexin family protein binding [GO:0042043]; phospholipid binding [GO:0005543]; Rab GTPase binding [GO:0017137]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; multivesicular body sorting pathway [GO:0071985]; negative regulation of insulin secretion [GO:0046676]; plasma membrane repair [GO:0001778]; platelet degranulation [GO:0002576]; positive regulation of exocytosis [GO:0045921]; positive regulation of protein secretion [GO:0050714]; regulation of plasma membrane repair [GO:1905684]	cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dense core granule [GO:0031045]; early phagosome [GO:0032009]; exocytic vesicle [GO:0070382]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of presynaptic membrane [GO:0099056]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; neuronal cell body [GO:0043025]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]; calcium ion regulated lysosome exocytosis [GO:1990927]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; regulation of synaptic vesicle endocytosis [GO:1900242]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119]; vesicle-mediated transport [GO:0016192]	intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; multivesicular body sorting pathway [GO:0071985]; negative regulation of insulin secretion [GO:0046676]; plasma membrane repair [GO:0001778]; platelet degranulation [GO:0002576]; positive regulation of exocytosis [GO:0045921]; positive regulation of protein secretion [GO:0050714]; regulation of plasma membrane repair [GO:1905684]	calcium-dependent activation of synaptic vesicle fusion [GO:0099502]; calcium-ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium ion regulated lysosome exocytosis [GO:1990927]; cellular response to calcium ion [GO:0071277]; detection of calcium ion [GO:0005513]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; regulation of synaptic vesicle endocytosis [GO:1900242]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119]; vesicle-mediated transport [GO:0016192]	endosome [GO:0005768]; exocytic vesicle [GO:0070382]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; transport vesicle membrane [GO:0030658]	cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dense core granule [GO:0031045]; early phagosome [GO:0032009]; exocytic vesicle [GO:0070382]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of presynaptic membrane [GO:0099056]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; neuronal cell body [GO:0043025]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]; neurexin family protein binding [GO:0042043]; phospholipid binding [GO:0005543]; Rab GTPase binding [GO:0017137]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; clathrin binding [GO:0030276]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; SNARE binding [GO:0000149]; syntaxin binding [GO:0019905]
d3fe1b2_d4xh4a2__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; neutrophil degranulation [GO:0043312]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]; L-threonine catabolic process to propionate [GO:0070689]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; neutrophil degranulation [GO:0043312]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	L-threonine catabolic process to propionate [GO:0070689]	blood microparticle [GO:0072562]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; propionate kinase activity [GO:0008980]
d3fe1b2_d5wfna1__1	Metazoa	Metazoa	Chordata	Arthropoda	blood microparticle [GO:0072562]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; neutrophil degranulation [GO:0043312]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; neutrophil degranulation [GO:0043312]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	blood microparticle [GO:0072562]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]
d3fe3b__d3kcfe___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of hippo signaling [GO:0035331]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein binding [GO:0032092]; protein phosphorylation [GO:0006468]	activin receptor complex [GO:0048179]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell surface [GO:0009986]; endosome [GO:0005768]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; activin binding [GO:0048185]; activin receptor activity, type I [GO:0016361]; ATP binding [GO:0005524]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity, type I [GO:0005025]; transforming growth factor beta-activated receptor activity [GO:0005024]; type II transforming growth factor beta receptor binding [GO:0005114]; activation of MAPKK activity [GO:0000186]; activin receptor signaling pathway [GO:0032924]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; epicardium morphogenesis [GO:1905223]; epithelial to mesenchymal transition [GO:0001837]; extracellular structure organization [GO:0043062]; germ cell migration [GO:0008354]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; protein deubiquitination [GO:0016579]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; regulation of transcription, DNA-templated [GO:0006355]; response to cholesterol [GO:0070723]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060]	intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of hippo signaling [GO:0035331]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein binding [GO:0032092]; protein phosphorylation [GO:0006468]	activation of MAPKK activity [GO:0000186]; activin receptor signaling pathway [GO:0032924]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; epicardium morphogenesis [GO:1905223]; epithelial to mesenchymal transition [GO:0001837]; extracellular structure organization [GO:0043062]; germ cell migration [GO:0008354]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; protein deubiquitination [GO:0016579]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; regulation of transcription, DNA-templated [GO:0006355]; response to cholesterol [GO:0070723]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]	activin receptor complex [GO:0048179]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell surface [GO:0009986]; endosome [GO:0005768]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]	activin binding [GO:0048185]; activin receptor activity, type I [GO:0016361]; ATP binding [GO:0005524]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta-activated receptor activity [GO:0005024]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity, type I [GO:0005025]; type II transforming growth factor beta receptor binding [GO:0005114]
d3fe6a__d4fqtb___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d3femc__d1j5ta1__1	Fungi		Ascomycota	Thermotogae	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	tryptophan biosynthetic process [GO:0000162]	glutaminase complex [GO:1903600]		amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]
d3femd__d3s9ya1__1	Fungi		Ascomycota	Apicomplexa	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	glutaminase complex [GO:1903600]		amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3ff6b1_d1xnwd2__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; endomembrane system [GO:0012505]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin binding [GO:0009374]; biotin carboxylase activity [GO:0004075]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; acetyl-CoA metabolic process [GO:0006084]; carnitine shuttle [GO:0006853]; energy homeostasis [GO:0097009]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of catalytic activity [GO:0043086]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; positive regulation of cellular metabolic process [GO:0031325]; positive regulation of heart growth [GO:0060421]; positive regulation of lipid storage [GO:0010884]; protein homotetramerization [GO:0051289]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of glucose metabolic process [GO:0010906]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	acetyl-CoA metabolic process [GO:0006084]; carnitine shuttle [GO:0006853]; energy homeostasis [GO:0097009]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of catalytic activity [GO:0043086]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; positive regulation of cellular metabolic process [GO:0031325]; positive regulation of heart growth [GO:0060421]; positive regulation of lipid storage [GO:0010884]; protein homotetramerization [GO:0051289]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of glucose metabolic process [GO:0010906]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; endomembrane system [GO:0012505]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	acetyl-CoA carboxylase complex [GO:0009317]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin binding [GO:0009374]; biotin carboxylase activity [GO:0004075]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]
d3ff7c__d1rdl2___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]
d3ff9a1_d3bx4a___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]	regulation of cytokine activity [GO:0060300]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d3ff9b1_d1kwwc1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d3ffcb1_d2hlff1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ffcb1_d4x7sl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ffdb2_d2gitb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; hormone activity [GO:0005179]; peptide hormone receptor binding [GO:0051428]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone mineralization [GO:0030282]; cAMP metabolic process [GO:0046058]; cell-cell signaling [GO:0007267]; epidermis development [GO:0008544]; female pregnancy [GO:0007565]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chondrocyte development [GO:0061182]; negative regulation of chondrocyte differentiation [GO:0032331]; osteoblast development [GO:0002076]; positive regulation of cell population proliferation [GO:0008284]; regulation of gene expression [GO:0010468]; skeletal system development [GO:0001501]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone mineralization [GO:0030282]; cAMP metabolic process [GO:0046058]; cell-cell signaling [GO:0007267]; epidermis development [GO:0008544]; female pregnancy [GO:0007565]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chondrocyte development [GO:0061182]; negative regulation of chondrocyte differentiation [GO:0032331]; osteoblast development [GO:0002076]; positive regulation of cell population proliferation [GO:0008284]; regulation of gene expression [GO:0010468]; skeletal system development [GO:0001501]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	hormone activity [GO:0005179]; peptide hormone receptor binding [GO:0051428]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ffka2_d1d0na4__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d3ffka2_d3fg6c3__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]
d3ffna1_d3ffna3__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d3ffna4_d5ubos___1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3ffnb2_d2fgha6__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d3ffnb5_d1m4ja___1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; filopodium [GO:0030175]; myofibril [GO:0030016]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; actin filament depolymerization [GO:0030042]; barbed-end actin filament capping [GO:0051016]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of neuron projection development [GO:0010976]; regulation of actin phosphorylation [GO:0043538]; regulation of lamellipodium assembly [GO:0010591]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament depolymerization [GO:0030042]; barbed-end actin filament capping [GO:0051016]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of neuron projection development [GO:0010976]; regulation of actin phosphorylation [GO:0043538]; regulation of lamellipodium assembly [GO:0010591]; sequestering of actin monomers [GO:0042989]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; filopodium [GO:0030175]; myofibril [GO:0030016]; perinuclear region of cytoplasm [GO:0048471]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]
d3ffnb6_d2vaca___1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament [GO:0005884]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; myofibril [GO:0030016]; perinuclear region of cytoplasm [GO:0048471]; stereocilium [GO:0032420]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; actin filament depolymerization [GO:0030042]; barbed-end actin filament capping [GO:0051016]; cell projection organization [GO:0030030]; cellular response to growth factor stimulus [GO:0071363]; cellular response to retinoic acid [GO:0071300]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of axon extension [GO:0045773]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neuron projection development [GO:0010976]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of lamellipodium assembly [GO:0010591]; regulation of microvillus length [GO:0032532]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament depolymerization [GO:0030042]; barbed-end actin filament capping [GO:0051016]; cell projection organization [GO:0030030]; cellular response to growth factor stimulus [GO:0071363]; cellular response to retinoic acid [GO:0071300]; negative regulation of actin filament polymerization [GO:0030837]; positive regulation of axon extension [GO:0045773]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neuron projection development [GO:0010976]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of lamellipodium assembly [GO:0010591]; regulation of microvillus length [GO:0032532]; sequestering of actin monomers [GO:0042989]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin filament [GO:0005884]; cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; myofibril [GO:0030016]; perinuclear region of cytoplasm [GO:0048471]; stereocilium [GO:0032420]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]
d3ffoa__d4av4a___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]; carbohydrate binding [GO:0030246]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]	carbohydrate binding [GO:0030246]	mannose binding [GO:0005537]
d3ffua__d2jvba___1		Fungi	Proteobacteria	Ascomycota	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; DNA repair [GO:0006281]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; Dcp1-Dcp2 complex [GO:0098745]; nucleus [GO:0005634]; P-body [GO:0000932]; chromatin binding [GO:0003682]; hydrolase activity [GO:0016787]; m7G(5')pppN diphosphatase activity [GO:0050072]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; mRNA processing [GO:0006397]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; stress granule assembly [GO:0034063]	DNA repair [GO:0006281]	deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; mRNA processing [GO:0006397]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; stress granule assembly [GO:0034063]		cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; Dcp1-Dcp2 complex [GO:0098745]; nucleus [GO:0005634]; P-body [GO:0000932]	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]	chromatin binding [GO:0003682]; hydrolase activity [GO:0016787]; m7G(5')pppN diphosphatase activity [GO:0050072]; manganese ion binding [GO:0030145]; mRNA binding [GO:0003729]
d3ffwa__d3eula___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	DNA binding [GO:0003677]
d3ffwb__d1a04b2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; nitrate assimilation [GO:0042128]; phosphorelay signal transduction system [GO:0000160]; regulation of gene expression [GO:0010468]; regulation of nitrate assimilation [GO:0090352]; regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	nitrate assimilation [GO:0042128]; phosphorelay signal transduction system [GO:0000160]; regulation of gene expression [GO:0010468]; regulation of nitrate assimilation [GO:0090352]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3ffxa__d3t8yb___1			Proteobacteria	Thermotogae	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; phosphorelay response regulator activity [GO:0000156]; protein-glutamate methylesterase activity [GO:0008984]; protein-glutamine glutaminase activity [GO:0050568]; chemotaxis [GO:0006935]; protein deamination [GO:0018277]; protein demethylation [GO:0006482]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	chemotaxis [GO:0006935]; protein deamination [GO:0018277]; protein demethylation [GO:0006482]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	phosphorelay response regulator activity [GO:0000156]; protein-glutamate methylesterase activity [GO:0008984]; protein-glutamine glutaminase activity [GO:0050568]
d3ffxb__d2b1jb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]	cytosol [GO:0005829]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d3fg0b1_d2bjkb___1				Deinococcus-Thermus		nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]						nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3fg0b1_d4i8pb___1		Viridiplantae		Streptophyta		1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]						1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]
d3fg0e1_d1ez0b___1				Proteobacteria		aldehyde dehydrogenase (NADP+) activity [GO:0033721]						aldehyde dehydrogenase (NADP+) activity [GO:0033721]
d3fg0f1_d1bpwb___1		Metazoa		Chordata		cytosol [GO:0005829]; 4-trimethylammoniobutyraldehyde dehydrogenase activity [GO:0047105]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; carnitine biosynthetic process [GO:0045329]		carnitine biosynthetic process [GO:0045329]		cytosol [GO:0005829]		4-trimethylammoniobutyraldehyde dehydrogenase activity [GO:0047105]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]
d3fg6a2_d1nm1g___1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d3fg6b2_d2fghb1__1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d3fg6c1_d1p8xb2__1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d3fg6c2_d1cofa___1	Metazoa	Fungi	Chordata	Ascomycota	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin cortical patch [GO:0030479]; actin cytoskeleton [GO:0015629]; nuclear matrix [GO:0016363]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin cortical patch [GO:0030479]; actin cytoskeleton [GO:0015629]; nuclear matrix [GO:0016363]; plasma membrane [GO:0005886]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]	actin filament binding [GO:0051015]
d3fg6d1_d5dd2g___1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d3fg6d2_d1hqz5___1	Metazoa	Fungi	Chordata	Ascomycota	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin filament binding [GO:0051015]; actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]	actin filament binding [GO:0051015]
d3fg6f2_d2fh1c2__1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d3fg6g1_d2fh2a2__1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d3fg6g2_d2fghb6__1	Metazoa	Metazoa	Chordata	Chordata	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium assembly [GO:0060271]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]
d3fg6h2_d1cfya___1	Metazoa	Fungi	Chordata	Ascomycota	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin cortical patch [GO:0030479]; actin cytoskeleton [GO:0015629]; nuclear matrix [GO:0016363]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]	actin filament capping [GO:0051693]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; calcium-ion regulated exocytosis [GO:0017156]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of actin nucleation [GO:0051127]; positive regulation of apoptotic process [GO:0043065]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of secretion [GO:0051047]; regulation of chondrocyte differentiation [GO:0032330]; sequestering of actin monomers [GO:0042989]	actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin filament severing [GO:0051014]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]	brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]	actin cortical patch [GO:0030479]; actin cytoskeleton [GO:0015629]; nuclear matrix [GO:0016363]; plasma membrane [GO:0005886]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]	actin filament binding [GO:0051015]
d3fgcd1_d1z69a___1			Proteobacteria	Euryarchaeota	alkanal monooxygenase (FMN-linked) activity [GO:0047646]; bioluminescence [GO:0008218]	cytoplasm [GO:0005737]; coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity [GO:0018537]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	bioluminescence [GO:0008218]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]		cytoplasm [GO:0005737]	alkanal monooxygenase (FMN-linked) activity [GO:0047646]	coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity [GO:0018537]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3fgma1_d3fjaa1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3fgmb1_d1q04a___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3fh4a__d3fvlc___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d3fh5a2_d1bzsa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3fh5a3_d2pkga1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	chromosome, centromeric region [GO:0000775]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; protein phosphatase regulator activity [GO:0019888]; protein serine/threonine phosphatase activity [GO:0004722]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; chromosome segregation [GO:0007059]; ciliary basal body-plasma membrane docking [GO:0097711]; female meiotic nuclear division [GO:0007143]; G2/M transition of mitotic cell cycle [GO:0000086]; inactivation of MAPK activity [GO:0000188]; meiotic sister chromatid cohesion, centromeric [GO:0051754]; meiotic spindle elongation [GO:0051232]; mitotic nuclear envelope reassembly [GO:0007084]; mitotic sister chromatid separation [GO:0051306]; negative regulation of cell growth [GO:0030308]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; protein-containing complex assembly [GO:0065003]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of growth [GO:0040008]; regulation of meiotic cell cycle process involved in oocyte maturation [GO:1903538]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; chromosome segregation [GO:0007059]; ciliary basal body-plasma membrane docking [GO:0097711]; female meiotic nuclear division [GO:0007143]; G2/M transition of mitotic cell cycle [GO:0000086]; inactivation of MAPK activity [GO:0000188]; meiotic sister chromatid cohesion, centromeric [GO:0051754]; meiotic spindle elongation [GO:0051232]; mitotic nuclear envelope reassembly [GO:0007084]; mitotic sister chromatid separation [GO:0051306]; negative regulation of cell growth [GO:0030308]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein-containing complex assembly [GO:0065003]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of growth [GO:0040008]; regulation of meiotic cell cycle process involved in oocyte maturation [GO:1903538]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	chromosome, centromeric region [GO:0000775]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; lateral plasma membrane [GO:0016328]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; protein phosphatase regulator activity [GO:0019888]; protein serine/threonine phosphatase activity [GO:0004722]
d3fh9a__d3wcwf___1	Metazoa	Metazoa	Chordata	Annelida	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3fhba1_d2rd6a1__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; catalytic activity [GO:0003824]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	catalytic activity [GO:0003824]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3fhba2_d5wrzb2__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]; catalytic activity [GO:0003824]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; negative regulation of isotype switching [GO:0045829]; negative regulation of telomerase RNA reverse transcriptase activity [GO:1905662]; positive regulation of DNA ligation [GO:0051106]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to site of double-strand break [GO:1990166]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	centriole [GO:0005814]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; site of double-strand break [GO:0035861]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	catalytic activity [GO:0003824]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3fhmb__d3fv6b___1			Proteobacteria	Firmicutes	nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; carbon catabolite repression of transcription [GO:0045013]		carbon catabolite repression of transcription [GO:0045013]			nucleotide binding [GO:0000166]	DNA binding [GO:0003677]
d3fhsa4_d4yqvc2__1		Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]		cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d3fhtb2_d3trfa___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleus [GO:0005634]	cytosol [GO:0005829]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]
d3fhvb__d1ay2a___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]	pilus [GO:0009289]; cell adhesion [GO:0007155]		cell adhesion [GO:0007155]	integral component of membrane [GO:0016021]	pilus [GO:0009289]		
d3fi5a__d1vdpa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3fi5c__d3txda___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3fi9a2_d2xxed2__1			Bacteroidetes		malate dehydrogenase activity [GO:0016615]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]		carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]				malate dehydrogenase activity [GO:0016615]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	
d3fiba__d1jc9a___1	Metazoa	Metazoa	Chordata	Arthropoda	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein metabolic process [GO:0044267]; cellular protein-containing complex assembly [GO:0034622]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cell-cell adhesion [GO:0098609]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein-containing complex assembly [GO:0034622]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of platelet aggregation [GO:0090331]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; platelet maturation [GO:0036345]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; post-translational protein modification [GO:0043687]; protein polymerization [GO:0051258]; protein secretion [GO:0009306]; response to calcium ion [GO:0051592]; toll-like receptor signaling pathway [GO:0002224]	cell-cell adhesion [GO:0098609]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; plasma membrane [GO:0005886]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]	extracellular region [GO:0005576]	cell adhesion molecule binding [GO:0050839]; extracellular matrix structural constituent [GO:0005201]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; structural molecule activity [GO:0005198]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3fiqb__d3pp6b___1	Metazoa	Metazoa	Chordata	Mollusca	extracellular region [GO:0005576]; odorant binding [GO:0005549]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cytoplasm [GO:0005737]; membrane [GO:0016020]; lipid binding [GO:0008289]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]	cytoplasm [GO:0005737]; membrane [GO:0016020]	odorant binding [GO:0005549]; small molecule binding [GO:0036094]	lipid binding [GO:0008289]
d3fisb__d4fisb___1			Proteobacteria	Proteobacteria	cytoplasmic nucleosome [GO:0000787]; cytosol [GO:0005829]; invertasome [GO:0031421]; nucleoid [GO:0009295]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; protein homodimerization activity [GO:0042803]; sequence-specific DNA binding [GO:0043565]; sequence-specific DNA binding, bending [GO:0044374]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; bacterial transcription [GO:0001121]; chromatin organization involved in regulation of transcription [GO:0034401]; positive regulation of DNA recombination [GO:0045911]; provirus excision [GO:0032359]; regulation of transcription, DNA-templated [GO:0006355]; response to radiation [GO:0009314]	cytoplasmic nucleosome [GO:0000787]; cytosol [GO:0005829]; invertasome [GO:0031421]; nucleoid [GO:0009295]; protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; protein homodimerization activity [GO:0042803]; sequence-specific DNA binding [GO:0043565]; sequence-specific DNA binding, bending [GO:0044374]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; bacterial transcription [GO:0001121]; chromatin organization involved in regulation of transcription [GO:0034401]; positive regulation of DNA recombination [GO:0045911]; provirus excision [GO:0032359]; regulation of transcription, DNA-templated [GO:0006355]; response to radiation [GO:0009314]	bacterial transcription [GO:0001121]; chromatin organization involved in regulation of transcription [GO:0034401]; positive regulation of DNA recombination [GO:0045911]; provirus excision [GO:0032359]; regulation of transcription, DNA-templated [GO:0006355]; response to radiation [GO:0009314]	bacterial transcription [GO:0001121]; chromatin organization involved in regulation of transcription [GO:0034401]; positive regulation of DNA recombination [GO:0045911]; provirus excision [GO:0032359]; regulation of transcription, DNA-templated [GO:0006355]; response to radiation [GO:0009314]	cytoplasmic nucleosome [GO:0000787]; cytosol [GO:0005829]; invertasome [GO:0031421]; nucleoid [GO:0009295]; protein-DNA complex [GO:0032993]	cytoplasmic nucleosome [GO:0000787]; cytosol [GO:0005829]; invertasome [GO:0031421]; nucleoid [GO:0009295]; protein-DNA complex [GO:0032993]	bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; protein homodimerization activity [GO:0042803]; sequence-specific DNA binding [GO:0043565]; sequence-specific DNA binding, bending [GO:0044374]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; protein homodimerization activity [GO:0042803]; sequence-specific DNA binding [GO:0043565]; sequence-specific DNA binding, bending [GO:0044374]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3fiya__d1dwhm___1		Viridiplantae		Streptophyta		vacuole [GO:0005773]; glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		vacuole [GO:0005773]		glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]
d3fiza__d1uwia1__1				Crenarchaeota		beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]
d3fj4b1_d2ggeb2__1			Proteobacteria	Firmicutes	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	cellular amino acid catabolic process [GO:0009063]				chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3fj9a1_d4xfsa___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d3fjbb1_d3ud9b___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3fjcb1_d1nzka___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3fjcb1_d31bia___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d3fjdb1_d3udaa___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3fjea1_d4p0ja___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; antifungal humoral response [GO:0019732]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-6 production [GO:0032715]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	antifungal humoral response [GO:0019732]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-6 production [GO:0032715]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]
d3fjfa1_d2aqza1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3fjha1_d1ioba___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d3fjhb1_d1barb___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; mesonephric epithelium development [GO:0072163]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3fjic1_d3bb2b1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3fjid1_d4x37a___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; acute-phase response [GO:0006953]; cellular response to cold [GO:0070417]; chemokine production [GO:0032602]; cortisol secretion [GO:0043400]; detection of lipopolysaccharide [GO:0032497]; fever generation [GO:0001660]; immune response [GO:0006955]; inflammatory response [GO:0006954]; leukocyte activation involved in inflammatory response [GO:0002269]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; positive regulation of cell division [GO:0051781]; positive regulation of inflammatory response [GO:0050729]; response to virus [GO:0009615]; sexual reproduction [GO:0019953]; toll-like receptor signaling pathway [GO:0002224]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	acute-phase response [GO:0006953]; cellular response to cold [GO:0070417]; chemokine production [GO:0032602]; cortisol secretion [GO:0043400]; detection of lipopolysaccharide [GO:0032497]; fever generation [GO:0001660]; immune response [GO:0006955]; inflammatory response [GO:0006954]; leukocyte activation involved in inflammatory response [GO:0002269]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; positive regulation of cell division [GO:0051781]; positive regulation of inflammatory response [GO:0050729]; response to virus [GO:0009615]; sexual reproduction [GO:0019953]; toll-like receptor signaling pathway [GO:0002224]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]
d3fjja1_d3fjid1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3fjjb1_d1dzda___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3fjkc1_d2fgfa___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]
d3fk2c__d2ngrb___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTP binding [GO:0005525]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; phospholipid binding [GO:0005543]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription corepressor activity [GO:0003714]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye development [GO:0043010]; cell migration [GO:0016477]; cellular response to extracellular stimulus [GO:0031668]; central nervous system neuron axonogenesis [GO:0021955]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain development [GO:0030900]; mammary gland development [GO:0030879]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular permeability [GO:0043116]; neural tube closure [GO:0001843]; neuron projection guidance [GO:0097485]; positive regulation of cilium assembly [GO:0045724]; positive regulation of neuron projection development [GO:0010976]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of axonogenesis [GO:0050770]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]; wound healing, spreading of cells [GO:0044319]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye development [GO:0043010]; cell migration [GO:0016477]; cellular response to extracellular stimulus [GO:0031668]; central nervous system neuron axonogenesis [GO:0021955]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain development [GO:0030900]; mammary gland development [GO:0030879]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; neural tube closure [GO:0001843]; neuron projection guidance [GO:0097485]; positive regulation of cilium assembly [GO:0045724]; positive regulation of neuron projection development [GO:0010976]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of axonogenesis [GO:0050770]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	actin cytoskeleton [GO:0015629]; ciliary basal body [GO:0036064]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	DNA binding [GO:0003677]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; phospholipid binding [GO:0005543]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription corepressor activity [GO:0003714]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]
d3fkka__d1b4ka___1			Proteobacteria	Proteobacteria	2-dehydro-3-deoxy-L-arabinonate dehydratase activity [GO:0047449]; protein homodimerization activity [GO:0042803]; L-arabinose catabolic process to 2-oxoglutarate [GO:0019570]	cytosol [GO:0005829]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]; heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	L-arabinose catabolic process to 2-oxoglutarate [GO:0019570]	heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]		cytosol [GO:0005829]	2-dehydro-3-deoxy-L-arabinonate dehydratase activity [GO:0047449]; protein homodimerization activity [GO:0042803]	porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]
d3fl8a1_d1luda___1			Firmicutes	Firmicutes	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3fl8b1_d1s3va___1		Metazoa	Firmicutes	Chordata	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3fl8b1_d4m2xc___1			Firmicutes	Actinobacteria	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]
d3fl8f1_d1pdba___1		Metazoa	Firmicutes	Chordata	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3fl8f1_d3fqza___1			Firmicutes		dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	
d3flcx1_d1okjc1__1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	tRNA threonylcarbamoyladenosine modification [GO:0002949]		cytosol [GO:0005829]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]
d3fluc1_d1onrb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; membrane [GO:0016020]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]
d3flud1_d1vlwa1__1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	lyase activity [GO:0016829]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]		4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	lyase activity [GO:0016829]
d3flva1_d2cb8b___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]; autophagy of peroxisome [GO:0030242]; fatty acid catabolic process [GO:0009062]	endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; perinuclear endoplasmic reticulum [GO:0097038]; benzodiazepine receptor binding [GO:0030156]; lipid binding [GO:0008289]; long-chain fatty acyl-CoA binding [GO:0036042]; protein dimerization activity [GO:0046983]; acyl-CoA metabolic process [GO:0006637]; phosphatidylcholine acyl-chain remodeling [GO:0036151]	autophagy of peroxisome [GO:0030242]; fatty acid catabolic process [GO:0009062]	acyl-CoA metabolic process [GO:0006637]; phosphatidylcholine acyl-chain remodeling [GO:0036151]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; perinuclear endoplasmic reticulum [GO:0097038]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	benzodiazepine receptor binding [GO:0030156]; lipid binding [GO:0008289]; long-chain fatty acyl-CoA binding [GO:0036042]; protein dimerization activity [GO:0046983]
d3flvb1_d2wh5b___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]; autophagy of peroxisome [GO:0030242]; fatty acid catabolic process [GO:0009062]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	autophagy of peroxisome [GO:0030242]; fatty acid catabolic process [GO:0009062]		integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]		fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]	fatty-acyl-CoA binding [GO:0000062]; lipid binding [GO:0008289]
d3fm1a__d1h58a___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; vacuole [GO:0005773]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3fm4a__d1sdqa___1	Fungi	Fungi	Basidiomycota	Ascomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3fm6a__d3ut2a2__1	Fungi	Fungi	Basidiomycota	Ascomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3fm6a__d5sx2b2__1	Fungi		Basidiomycota	Proteobacteria	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3fmgl1_d1mfcl2__1					host cell endoplasmic reticulum lumen [GO:0044166]; T=13 icosahedral viral capsid [GO:0039621]; viral outer capsid [GO:0039624]; metal ion binding [GO:0046872]; receptor-mediated virion attachment to host cell [GO:0046813]		receptor-mediated virion attachment to host cell [GO:0046813]		host cell endoplasmic reticulum lumen [GO:0044166]; T=13 icosahedral viral capsid [GO:0039621]; viral outer capsid [GO:0039624]		metal ion binding [GO:0046872]	
d3fmpd__d1s3sd2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleus [GO:0005634]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d3fmua__d3vlkb1__1	Fungi		Basidiomycota	Euryarchaeota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3fmza__d5ljda___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; protein heterodimerization activity [GO:0046982]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]; cardiac muscle tissue development [GO:0048738]; embryonic organ morphogenesis [GO:0048562]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; female genitalia morphogenesis [GO:0048807]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; lung development [GO:0030324]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; urinary bladder development [GO:0060157]; uterus development [GO:0060065]; vagina development [GO:0060068]; visual perception [GO:0007601]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; lipid homeostasis [GO:0055088]; retinoic acid biosynthetic process [GO:0002138]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cardiac muscle tissue development [GO:0048738]; embryonic organ morphogenesis [GO:0048562]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; female genitalia morphogenesis [GO:0048807]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; lung development [GO:0030324]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; urinary bladder development [GO:0060157]; uterus development [GO:0060065]; vagina development [GO:0060068]; visual perception [GO:0007601]	lipid homeostasis [GO:0055088]; retinoic acid biosynthetic process [GO:0002138]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]	protein heterodimerization activity [GO:0046982]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]
d3fn0l2_d5hdql1__1				Firmicutes		metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]		cell adhesion [GO:0007155]; metal ion transport [GO:0030001]				metal ion binding [GO:0046872]
d3fn1b__d4onlb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]; cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]	ubiquitin conjugating enzyme activity [GO:0061631]
d3fn8a1_d4ld5e___1			Proteobacteria	Firmicutes	alkylmercury lyase activity [GO:0018836]; organomercury catabolic process [GO:0046413]; response to mercury ion [GO:0046689]	DNA-binding transcription factor activity [GO:0003700]	organomercury catabolic process [GO:0046413]; response to mercury ion [GO:0046689]				alkylmercury lyase activity [GO:0018836]	DNA-binding transcription factor activity [GO:0003700]
d3fn8a2_d2hq3a___1			Proteobacteria	Proteobacteria	alkylmercury lyase activity [GO:0018836]; organomercury catabolic process [GO:0046413]; response to mercury ion [GO:0046689]	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]	organomercury catabolic process [GO:0046413]; response to mercury ion [GO:0046689]			plasma membrane [GO:0005886]	alkylmercury lyase activity [GO:0018836]	metal ion binding [GO:0046872]
d3fnea__d2grac1__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d3fnkc__d1js4a2__1			Firmicutes	Actinobacteria	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]			carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d3fnkc__d4c8xc___1			Firmicutes	Firmicutes	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d3fo0l1_d1zmya1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3fo0l1_d4dqol2__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d3fo1a1_d5f93f1__1				Proteobacteria								
d3fo1a2_d1jbja1__1		Metazoa		Chordata		alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SH3 domain binding [GO:0017124]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; lymphocyte activation [GO:0046649]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; response to nutrient [GO:0007584]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; lymphocyte activation [GO:0046649]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; response to nutrient [GO:0007584]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]		alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SH3 domain binding [GO:0017124]; transmembrane signaling receptor activity [GO:0004888]
d3fo1l1_d5mvgb1__1												
d3fo1l2_d5gs1k1__1												
d3fo1l2_d5lxgh___1		Metazoa		Chordata		integral component of membrane [GO:0016021]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]; adipokinetic hormone receptor activity [GO:0097003]; adiponectin binding [GO:0055100]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; leptin-mediated signaling pathway [GO:0033210]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid metabolic process [GO:0019216]		adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; leptin-mediated signaling pathway [GO:0033210]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid metabolic process [GO:0019216]		integral component of membrane [GO:0016021]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]		adipokinetic hormone receptor activity [GO:0097003]; adiponectin binding [GO:0055100]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]
d3fo2a2_d4x6eb___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3fo2l1_d4k3hc___1												
d3fo2l2_d4hiea2__1												
d3fo9a2_d5trpl1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3fo9b1_d1nldl1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3fo9b2_d3utpe1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3fo9l2_d1ahwa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3folb1_d4w4nb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3fomb1_d4ozha2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3fond1_d5eb9a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3fooa__d2xloa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3fooa__d3m4cc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3foob__d3m79a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3fooc__d2xlea___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3food__d1gqaa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3foof__d4cx9b___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3fooh__d2xlha___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3fooh__d3iq6c___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3fooi__d2ccyb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3fooj__d1cgoa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3fook__d4wgya___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3fool__d3hnjb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3fp6e__d1xvoa___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]	serine-type endopeptidase activity [GO:0004252]
d3fp6e__d2wv5d___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3fp7e__d4ncya___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3fp8e__d1o3ka___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3fpba4_d2dqsa4__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	calcium ion import into sarcoplasmic reticulum [GO:1990036]; calcium ion transport [GO:0006816]; negative regulation of striated muscle contraction [GO:0045988]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of calcium ion import into sarcoplasmic reticulum [GO:1902082]; positive regulation of cardiac muscle cell contraction [GO:0106134]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; regulation of striated muscle contraction [GO:0006942]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; H zone [GO:0031673]; I band [GO:0031674]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum membrane [GO:0033017]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]
d3fpka2_d4dqlb2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]			cytosol [GO:0005829]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d3fpxa1_d1l9pc2__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3fpxa3_d1nwob___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3fpya__d1hfua1__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3fq0a__d3ql0a___1				Proteobacteria		dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]		glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3fq1a__d1aspa2__1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	extracellular region [GO:0005576]; copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; L-ascorbate oxidase activity [GO:0008447]
d3fq2a__d1aznc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3fq3c__d2ik4b___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3fq3f__d3r5ve___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3fq3g__d1e6ab___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3fq3i__d3q3lb___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3fq7b__d1yooa___1			Cyanobacteria	Proteobacteria	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d3fqca__d2anoa___1				Proteobacteria		cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d3fqca__d4km0b1__1				Actinobacteria		cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]
d3fqcb__d1u72a___1		Metazoa		Chordata		cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3fqrb__d1mwad2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3fqtb__d5nsga1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3fqya__d5i6oa2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3fr2a__d4ge1c___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	histamine binding [GO:0051381]; nitric oxide binding [GO:0070026]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]		fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	histamine binding [GO:0051381]; nitric oxide binding [GO:0070026]
d3fr2a__d4qgwb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3fr3a1_d1e6ba2__1		Viridiplantae	Apicomplexa	Streptophyta	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; maleylacetoacetate isomerase activity [GO:0016034]; peroxidase activity [GO:0004601]; aromatic amino acid family metabolic process [GO:0009072]; glutathione metabolic process [GO:0006749]; homogentisate catabolic process [GO:1902000]; toxin catabolic process [GO:0009407]		aromatic amino acid family metabolic process [GO:0009072]; glutathione metabolic process [GO:0006749]; homogentisate catabolic process [GO:1902000]; toxin catabolic process [GO:0009407]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]; maleylacetoacetate isomerase activity [GO:0016034]; peroxidase activity [GO:0004601]
d3fr3a1_d3drnb___1			Apicomplexa	Crenarchaeota	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytoplasm [GO:0005737]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]		cell [GO:0005623]; cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]	thioredoxin peroxidase activity [GO:0008379]
d3fr3a2_d1eohd1__1		Metazoa	Apicomplexa	Chordata	glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3fr4a__d4o9sb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; protein heterodimerization activity [GO:0046982]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]; cardiac muscle tissue development [GO:0048738]; embryonic organ morphogenesis [GO:0048562]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; female genitalia morphogenesis [GO:0048807]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; lung development [GO:0030324]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; urinary bladder development [GO:0060157]; uterus development [GO:0060065]; vagina development [GO:0060068]; visual perception [GO:0007601]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cardiac muscle tissue development [GO:0048738]; embryonic organ morphogenesis [GO:0048562]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic skeletal system development [GO:0048706]; eye development [GO:0001654]; female genitalia morphogenesis [GO:0048807]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; lung development [GO:0030324]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; urinary bladder development [GO:0060157]; uterus development [GO:0060065]; vagina development [GO:0060068]; visual perception [GO:0007601]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	protein heterodimerization activity [GO:0046982]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]
d3fr4a__d5ljka___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; lipid homeostasis [GO:0055088]; retinoic acid biosynthetic process [GO:0002138]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	lipid homeostasis [GO:0055088]; retinoic acid biosynthetic process [GO:0002138]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]
d3fr5a__d3wjfb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	cytosol [GO:0005829]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	
d3fr6a1_d5a4uf1__1		Viridiplantae	Apicomplexa	Streptophyta	glutathione transferase activity [GO:0004364]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	glutathione transferase activity [GO:0004364]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d3fr7a2_d4xiyc2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; mitochondrion [GO:0005739]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	chloroplast [GO:0009507]; mitochondrion [GO:0005739]		ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADP binding [GO:0050661]
d3fr7b1_d1pzfc1__1	Viridiplantae		Streptophyta	Apicomplexa	chloroplast [GO:0009507]; mitochondrion [GO:0005739]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	chloroplast [GO:0009507]; mitochondrion [GO:0005739]		ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d3fr7b2_d5uaue2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; mitochondrion [GO:0005739]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	chloroplast [GO:0009507]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d3fr8a1_d1q7ca___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; mitochondrion [GO:0005739]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cytosol [GO:0005829]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]	chloroplast [GO:0009507]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3fr8a2_d5uawb2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; mitochondrion [GO:0005739]; ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	chloroplast [GO:0009507]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ketol-acid reductoisomerase activity [GO:0004455]; magnesium ion binding [GO:0000287]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d3frbx__d3qyla___1			Firmicutes	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d3frdx__d3eema1__1		Fungi	Firmicutes	Ascomycota	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d3frfx__d5uiob___1			Firmicutes	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d3frjb1_d1p44d___1	Metazoa		Chordata	Actinobacteria	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d3frjb1_d1v9le1__1	Metazoa		Chordata	Crenarchaeota	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cellular amino acid metabolic process [GO:0006520]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d3frob1_d3froa1__1			Euryarchaeota	Euryarchaeota	glycogen (starch) synthase activity [GO:0004373]; nucleotide binding [GO:0000166]	glycogen (starch) synthase activity [GO:0004373]; nucleotide binding [GO:0000166]					glycogen (starch) synthase activity [GO:0004373]; nucleotide binding [GO:0000166]	glycogen (starch) synthase activity [GO:0004373]; nucleotide binding [GO:0000166]
d3frua2_d3dbxa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3frub__d3wfcl2__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]; aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]		cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]
d3fruc1_d3vgab1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	axolemma [GO:0030673]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; intermediate filament [GO:0005882]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; alpha-actinin binding [GO:0051393]; enzyme binding [GO:0019899]; G protein-coupled adenosine receptor activity [GO:0001609]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; type 5 metabotropic glutamate receptor binding [GO:0031802]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; cellular protein metabolic process [GO:0044267]; central nervous system development [GO:0007417]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of transcription, DNA-templated [GO:0006355]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; sensory perception [GO:0007600]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; cellular protein metabolic process [GO:0044267]; central nervous system development [GO:0007417]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of transcription, DNA-templated [GO:0006355]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; sensory perception [GO:0007600]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	axolemma [GO:0030673]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; intermediate filament [GO:0005882]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]		alpha-actinin binding [GO:0051393]; enzyme binding [GO:0019899]; G protein-coupled adenosine receptor activity [GO:0001609]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d3frud__d5cd3f1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]			
d3fruf__d5hdbl2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3fs7e__d1c7wa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]	cytoplasm [GO:0005737]; calcium ion binding [GO:0005509]			cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]
d3fs7f__d1dvib___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; proteolysis [GO:0006508]		proteolysis [GO:0006508]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]
d3fs7h__d2pala___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]; calcium ion binding [GO:0005509]			cytoplasm [GO:0005737]; nucleus [GO:0005634]	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]
d3fs9a__d3l45a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3fs9a__d4eslb2__1			Proteobacteria		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	
d3fshb1_d2dawa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; dendrite [GO:0030425]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; BAT3 complex binding [GO:1904288]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-specific protease binding [GO:1990381]; ubiquitin-ubiquitin ligase activity [GO:0034450]; aging [GO:0007568]; endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; learning or memory [GO:0007611]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of protein binding [GO:0032092]; protein autoubiquitination [GO:0051865]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]		aging [GO:0007568]; endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; learning or memory [GO:0007611]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of protein binding [GO:0032092]; protein autoubiquitination [GO:0051865]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]		cytosol [GO:0005829]; dendrite [GO:0030425]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]		BAT3 complex binding [GO:1904288]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-specific protease binding [GO:1990381]; ubiquitin-ubiquitin ligase activity [GO:0034450]	
d3fsjx2_d3riyb1__1		Metazoa	Proteobacteria	Chordata	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	mandelate catabolic process [GO:0019596]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3fswa__d1j9tb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3fswd__d4a2ga1__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3fszb__d9pcya___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3ft1a1_d1n10b1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]	extracellular region [GO:0005576]; sexual reproduction [GO:0019953]		sexual reproduction [GO:0019953]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d3ft1b1_d1whpa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]	extracellular region [GO:0005576]			extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d3ft1c1_d1n10a1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]	extracellular region [GO:0005576]; sexual reproduction [GO:0019953]		sexual reproduction [GO:0019953]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d3ft3b1_d2iand1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ft9a__d2vxqa___1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ftba__d5e4za___1			Firmicutes	Proteobacteria	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	biosynthetic process [GO:0009058]	transsulfuration [GO:0019346]			pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d3ftfa__d3kqva___1		Metazoa	Aquificae	Chordata	cytoplasm [GO:0005737]; 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity [GO:0052908]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]; rRNA methylation [GO:0031167]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	rRNA methylation [GO:0031167]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity [GO:0052908]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d3ftgb1_d4l3ca2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ftpa__d4oknc1__1		Metazoa	Proteobacteria	Chordata	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	fatty acid biosynthetic process [GO:0006633]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d3ftsa2_d5czma___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3ftwa1_d4nz8a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3ftya1_d4hola1__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]		aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	
d3ftza2_d2ow2b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3fu0a2_d1kufa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]
d3fu5a1_d4fyra1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3fu6a2_d3msaa___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3fu7a2_d1bqra___1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		extraorganismal space [GO:0043245]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3fu7a3_d3ay2b___1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		extraorganismal space [GO:0043245]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3fu8a2_d5ue6e2__1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	nitrogen compound metabolic process [GO:0006807]	extraorganismal space [GO:0043245]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3fu8a3_d3fu7b2__1	Fungi	Fungi	Ascomycota	Ascomycota	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	extraorganismal space [GO:0043245]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3fu8b2_d2vw4a1__1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	nitrogen compound metabolic process [GO:0006807]	extraorganismal space [GO:0043245]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3fu8b3_d1niab1__1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	extraorganismal space [GO:0043245]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3fu9a1_d1as8a2__1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	extraorganismal space [GO:0043245]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3fu9b1_d1xb6a___1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	oxidation-reduction process [GO:0055114]	extraorganismal space [GO:0043245]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3fuea2_d3lk8a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3fuha2_d1os2f1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3fuja2_d5i43a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3fuka1_d3qnfa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; aminopeptidase activity [GO:0004177]; interleukin-1, type II receptor binding [GO:0005151]; interleukin-6 receptor binding [GO:0005138]; metalloaminopeptidase activity [GO:0070006]; metalloexopeptidase activity [GO:0008235]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; fat cell differentiation [GO:0045444]; membrane protein ectodomain proteolysis [GO:0006509]; peptide catabolic process [GO:0043171]; positive regulation of angiogenesis [GO:0045766]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of innate immune response [GO:0045088]; response to bacterium [GO:0009617]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; fat cell differentiation [GO:0045444]; membrane protein ectodomain proteolysis [GO:0006509]; peptide catabolic process [GO:0043171]; positive regulation of angiogenesis [GO:0045766]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of innate immune response [GO:0045088]; response to bacterium [GO:0009617]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; interleukin-1, type II receptor binding [GO:0005151]; interleukin-6 receptor binding [GO:0005138]; metalloaminopeptidase activity [GO:0070006]; metalloexopeptidase activity [GO:0008235]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270]
d3fuka2_d1rmza1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3fuoa1_d1bkza___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	negative regulation of neurotransmitter secretion [GO:0046929]	apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	carbohydrate binding [GO:0030246]
d3fuqa1_d1bxhb___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; membrane [GO:0016020]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; membrane [GO:0016020]		lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3fuqa1_d5vkia___1			Firmicutes		extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; membrane [GO:0016020]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	negative regulation of neurotransmitter secretion [GO:0046929]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; membrane [GO:0016020]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	
d3fuxa__d4e30a___1			Deinococcus-Thermus	Actinobacteria	cytoplasm [GO:0005737]; 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity [GO:0052908]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]	metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]			cytoplasm [GO:0005737]		16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity [GO:0052908]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]	metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]
d3fuza__d1lsta___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; amino acid transport [GO:0006865]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	amino acid transport [GO:0006865]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]	outer membrane-bounded periplasmic space [GO:0030288]	glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d3fuzb__d1my3c___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3fuzb__d4rg5a___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3fv1b__d2o7uc___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d3fv3f__d1n49b___1	Fungi		Ascomycota		extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3fv3f__d3c9xa___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]			extracellular region [GO:0005576]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d3fv9c2_d3ujra2__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3fv9d2_d2akza1__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3fvda2_d1sjaa1__1			Proteobacteria	Actinobacteria	metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]		menaquinone biosynthetic process [GO:0009234]			metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3fvga__d4iy5a1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3fvkb__d5crya___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; bone morphogenesis [GO:0060349]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]	cell surface [GO:0009986]; extracellular space [GO:0005615]; other organism cell membrane [GO:0044218]; protein-containing complex [GO:0032991]; specific granule [GO:0042581]	glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3fvla__d2pj0b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d3fvnb__d1n3xa___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3fvpa__d3o2xb1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]		bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d3fvrd__d1yajd1__1		Metazoa	Firmicutes	Chordata	acetylesterase activity [GO:0008126]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	acetylesterase activity [GO:0008126]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d3fvrg__d4x00a___1			Firmicutes	Proteobacteria	acetylesterase activity [GO:0008126]	hydrolase activity [GO:0016787]					acetylesterase activity [GO:0008126]	hydrolase activity [GO:0016787]
d3fvri__d3stvb___1		Viridiplantae	Firmicutes	Streptophyta	acetylesterase activity [GO:0008126]						acetylesterase activity [GO:0008126]	
d3fvrm__d5xh2a1__1			Firmicutes	Proteobacteria	acetylesterase activity [GO:0008126]	extracellular region [GO:0005576]; carboxylic ester hydrolase activity [GO:0052689]; cellular response to organic substance [GO:0071310]; xenobiotic catabolic process [GO:0042178]		cellular response to organic substance [GO:0071310]; xenobiotic catabolic process [GO:0042178]		extracellular region [GO:0005576]	acetylesterase activity [GO:0008126]	carboxylic ester hydrolase activity [GO:0052689]
d3fvrn__d3fytl___1			Firmicutes	Firmicutes	acetylesterase activity [GO:0008126]	acetylesterase activity [GO:0008126]					acetylesterase activity [GO:0008126]	acetylesterase activity [GO:0008126]
d3fvta__d3r3za1__1			Firmicutes	Proteobacteria	acetylesterase activity [GO:0008126]	haloacetate dehalogenase activity [GO:0018785]					acetylesterase activity [GO:0008126]	haloacetate dehalogenase activity [GO:0018785]
d3fvtb__d1odth___1			Firmicutes	Firmicutes	acetylesterase activity [GO:0008126]	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]		cellulose catabolic process [GO:0030245]; polysaccharide metabolic process [GO:0005976]		cytoplasm [GO:0005737]	acetylesterase activity [GO:0008126]	acetylxylan esterase activity [GO:0046555]; cephalosporin-C deacetylase activity [GO:0047739]
d3fvtc__d5tnfa___1			Firmicutes	Proteobacteria	acetylesterase activity [GO:0008126]	hydrolase activity [GO:0016787]					acetylesterase activity [GO:0008126]	hydrolase activity [GO:0016787]
d3fvtd__d2xlbf___1			Firmicutes	Firmicutes	acetylesterase activity [GO:0008126]	acetylesterase activity [GO:0008126]					acetylesterase activity [GO:0008126]	acetylesterase activity [GO:0008126]
d3fvtf__d4ke8b___1			Firmicutes	Firmicutes	acetylesterase activity [GO:0008126]	acylglycerol lipase activity [GO:0047372]					acetylesterase activity [GO:0008126]	acylglycerol lipase activity [GO:0047372]
d3fvtg__d1x70a2__1		Metazoa	Firmicutes	Chordata	acetylesterase activity [GO:0008126]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	acetylesterase activity [GO:0008126]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3fvtm__d3w9bc___1		Fungi	Firmicutes	Basidiomycota	acetylesterase activity [GO:0008126]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]			acetylesterase activity [GO:0008126]	triglyceride lipase activity [GO:0004806]
d3fvtn__d4updb___1		Fungi	Firmicutes	Ascomycota	acetylesterase activity [GO:0008126]	hydrolase activity [GO:0016787]					acetylesterase activity [GO:0008126]	hydrolase activity [GO:0016787]
d3fw1a__d1flda___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3fw4a__d2akqb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	extracellular region [GO:0005576]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]
d3fw5a__d4qzud___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytosol [GO:0005829]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3fwba__d1y0vh1__1	Fungi	Metazoa	Ascomycota	Chordata	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]; chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]; histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	calcium-mediated signaling [GO:0019722]	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]		chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]
d3fwba__d5csnb1__1	Fungi	Metazoa	Ascomycota	Chordata	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]; chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]; histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d3fwci__d2colb___1	Fungi	Metazoa	Ascomycota	Chordata	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]; chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]; histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	calcium-mediated signaling [GO:0019722]	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]		chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]
d3fwci__d3nsla___1	Fungi	Metazoa	Ascomycota	Chordata	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]; chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]; histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]	histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]		DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]	calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]
d3fwcm__d3cgab___1	Fungi	Metazoa	Ascomycota	Chordata	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]; chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]; histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d3fwrb__d4zhxf1__1		Metazoa	Firmicutes	Chordata	DNA binding [GO:0003677]; carbon catabolite repression of transcription [GO:0045013]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; AMP-activated protein kinase activity [GO:0004679]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; cell cycle arrest [GO:0007050]; fatty acid biosynthetic process [GO:0006633]; macroautophagy [GO:0016236]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of signal transduction by p53 class mediator [GO:1901796]; signal transduction [GO:0007165]	carbon catabolite repression of transcription [GO:0045013]	cell cycle arrest [GO:0007050]; fatty acid biosynthetic process [GO:0006633]; macroautophagy [GO:0016236]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of signal transduction by p53 class mediator [GO:1901796]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]	DNA binding [GO:0003677]	AMP-activated protein kinase activity [GO:0004679]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]
d3fwsa__d3kpba___1			Firmicutes	Euryarchaeota	DNA binding [GO:0003677]; carbon catabolite repression of transcription [GO:0045013]		carbon catabolite repression of transcription [GO:0045013]				DNA binding [GO:0003677]	
d3fwta1_d4p01c___1		Metazoa		Chordata		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d3fwya__d1e0kc___1			Proteobacteria		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on iron-sulfur proteins as donors [GO:0016730]; oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor [GO:0016636]; light-independent bacteriochlorophyll biosynthetic process [GO:0036070]; photosynthesis, dark reaction [GO:0019685]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	light-independent bacteriochlorophyll biosynthetic process [GO:0036070]; photosynthesis, dark reaction [GO:0019685]				4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on iron-sulfur proteins as donors [GO:0016730]; oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor [GO:0016636]	ATP binding [GO:0005524]; DNA helicase activity [GO:0003678]; DNA primase activity [GO:0003896]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d3fx4a__d2vdga___1	Metazoa	Viridiplantae	Chordata	Streptophyta	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; glucuronolactone reductase activity [GO:0047941]; L-glucuronate reductase activity [GO:0047939]; mevaldate reductase (NADPH) activity [GO:0019726]; oxidoreductase activity [GO:0016491]; aldehyde catabolic process [GO:0046185]; cellular detoxification of aldehyde [GO:0110095]; D-glucuronate catabolic process [GO:0042840]; L-ascorbic acid biosynthetic process [GO:0019853]	alditol:NADP+ 1-oxidoreductase activity [GO:0004032]	aldehyde catabolic process [GO:0046185]; cellular detoxification of aldehyde [GO:0110095]; D-glucuronate catabolic process [GO:0042840]; L-ascorbic acid biosynthetic process [GO:0019853]		apical plasma membrane [GO:0016324]; cytosol [GO:0005829]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; glucuronolactone reductase activity [GO:0047941]; L-glucuronate reductase activity [GO:0047939]; mevaldate reductase (NADPH) activity [GO:0019726]; oxidoreductase activity [GO:0016491]	alditol:NADP+ 1-oxidoreductase activity [GO:0004032]
d3fx5b__d5oz9a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3fx6c__d3b7ia___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]	proteolysis [GO:0006508]		extracellular space [GO:0005615]	extracellular region [GO:0005576]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; metal ion binding [GO:0046872]
d3fx6e__d1hdub___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d3fxba__d3h6ta1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; C4-dicarboxylate transmembrane transporter activity [GO:0015556]; C4-dicarboxylate transport [GO:0015740]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	C4-dicarboxylate transport [GO:0015740]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	C4-dicarboxylate transmembrane transporter activity [GO:0015556]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3fxsa__d1mnca___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]		collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3fy8x__d3sa1b1__1			Firmicutes	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d3fyeb2_d2j55a___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3fyed2_d2cala___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3fyib2_d1j9rc2__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3fyib2_d5b1bo2__1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]		ATP synthesis coupled electron transport [GO:0042773]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d3fytb__d4ffwa2__1		Metazoa	Firmicutes	Chordata	acetylesterase activity [GO:0008126]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]		cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	acetylesterase activity [GO:0008126]	collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3fytb__d5jibc___1			Firmicutes	Thermotogae	acetylesterase activity [GO:0008126]	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]		cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]		cytoplasm [GO:0005737]	acetylesterase activity [GO:0008126]	acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]
d3fytc__d2gbfb2__1		Metazoa	Firmicutes	Chordata	acetylesterase activity [GO:0008126]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]		cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	acetylesterase activity [GO:0008126]	collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3fytg__d5tnra___1			Firmicutes	Proteobacteria	acetylesterase activity [GO:0008126]	hydrolase activity [GO:0016787]					acetylesterase activity [GO:0008126]	hydrolase activity [GO:0016787]
d3fyti__d1ju4a2__1			Firmicutes	Actinobacteria	acetylesterase activity [GO:0008126]	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]		cocaine catabolic process [GO:0050784]		cytoplasm [GO:0005737]	acetylesterase activity [GO:0008126]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]
d3fytn__d5tnkb___1			Firmicutes	Proteobacteria	acetylesterase activity [GO:0008126]	hydrolase activity [GO:0016787]					acetylesterase activity [GO:0008126]	hydrolase activity [GO:0016787]
d3fyuc__d3jweb___1		Metazoa	Firmicutes	Chordata	acetylesterase activity [GO:0008126]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; acylglycerol lipase activity [GO:0047372]; lysophospholipase activity [GO:0004622]; protein homodimerization activity [GO:0042803]; acylglycerol acyl-chain remodeling [GO:0036155]; acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; monoacylglycerol catabolic process [GO:0052651]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433]		acylglycerol acyl-chain remodeling [GO:0036155]; acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; monoacylglycerol catabolic process [GO:0052651]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	acetylesterase activity [GO:0008126]	acylglycerol lipase activity [GO:0047372]; lysophospholipase activity [GO:0004622]; protein homodimerization activity [GO:0042803]
d3fyug__d5gmac1__1			Firmicutes	Thermotogae	acetylesterase activity [GO:0008126]	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]		cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]		cytoplasm [GO:0005737]	acetylesterase activity [GO:0008126]	acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]
d3fyum__d5fdfc___1			Firmicutes	Thermotogae	acetylesterase activity [GO:0008126]	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]		cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]		cytoplasm [GO:0005737]	acetylesterase activity [GO:0008126]	acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]
d3fywx__d1rh3a___1			Firmicutes	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d3fywx__d3ix9a___1			Firmicutes	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3fyya2_d2dw7l1__1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]		protein homooligomerization [GO:0051260]			lyase activity [GO:0016829]; metal ion binding [GO:0046872]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]
d3fz6d__d3nmya___1			Proteobacteria		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]		glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]	
d3fz7a__d1bs0a___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	8-amino-7-oxononanoate synthase activity [GO:0008710]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	biotin biosynthetic process [GO:0009102]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]	8-amino-7-oxononanoate synthase activity [GO:0008710]; pyridoxal phosphate binding [GO:0030170]
d3fz7e__d1v2ea___1			Proteobacteria	Deinococcus-Thermus	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	biosynthetic process [GO:0009058]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d3fz7f__d5x2xa___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	transsulfuration [GO:0019346]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d3fz8d__d5vera___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; kynurenine-glyoxylate transaminase activity [GO:0047315]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]; kynurenine metabolic process [GO:0070189]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]; kynurenine metabolic process [GO:0070189]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]	cysteine-S-conjugate beta-lyase activity [GO:0047804]; kynurenine-glyoxylate transaminase activity [GO:0047315]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]
d3fz8f__d1i43a___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	transsulfuration [GO:0019346]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d3fzia1_d3w2ya___1			Euryarchaeota	Euryarchaeota	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	DNA repair [GO:0006281]	DNA repair [GO:0006281]			DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d3fzka1_d1y64a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3fzka2_d2p9nb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]	actin filament binding [GO:0051015]
d3fzma1_d2q31a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3fzna1_d3dv0b1__1			Proteobacteria	Firmicutes	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	mandelate catabolic process [GO:0019596]	glycolytic process [GO:0006096]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d3fznb1_d2v3wc3__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	mandelate catabolic process [GO:0019596]	mandelate catabolic process [GO:0019596]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3fznb3_d2ji6a3__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]; oxalate catabolic process [GO:0033611]	mandelate catabolic process [GO:0019596]	oxalate catabolic process [GO:0033611]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	ADP binding [GO:0043531]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; oxalyl-CoA decarboxylase activity [GO:0008949]; thiamine pyrophosphate binding [GO:0030976]
d3fznc2_d1pnob1__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]	mandelate catabolic process [GO:0019596]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]
d3fznc3_d4k9na3__1			Proteobacteria	Proteobacteria	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	mandelate catabolic process [GO:0019596]	mandelate catabolic process [GO:0019596]			benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3fznd2_d1v5fa1__1			Proteobacteria		benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]				benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]	
d3fzwb__d1jb4b___1		Metazoa	Proteobacteria	Chordata	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	steroid metabolic process [GO:0008202]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]		cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	steroid delta-isomerase activity [GO:0004769]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]
d3fzza__d1mbmd___1	Metazoa		Chordata		cytoplasm [GO:0005737]; serine-type endopeptidase activity [GO:0004252]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	host cell membrane [GO:0033644]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	cytoplasm [GO:0005737]	host cell membrane [GO:0033644]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3fzza__d1o3p.1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; serine-type endopeptidase activity [GO:0004252]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	cytoplasm [GO:0005737]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d3fzzb__d1nu9a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; serine-type endopeptidase activity [GO:0004252]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d3g00a1_d4k6lf___1			Euryarchaeota	Proteobacteria	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; toxin activity [GO:0090729]	DNA repair [GO:0006281]			extracellular region [GO:0005576]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; toxin activity [GO:0090729]
d3g00a1_d4qh9a___1		Metazoa	Euryarchaeota	Chordata	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	DNA repair [GO:0006281]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]		cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]
d3g00b__d1vyba___1		Metazoa	Euryarchaeota	Chordata	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	metal ion binding [GO:0046872]; RNA-directed DNA polymerase activity [GO:0003964]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197]	DNA repair [GO:0006281]	DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197]			DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; RNA-directed DNA polymerase activity [GO:0003964]; type II site-specific deoxyribonuclease activity [GO:0009036]
d3g03a__d2vyra___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; 5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]
d3g04a1_d1q9ra3__1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]; activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]		activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]		basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]	
d3g04a2_d5m6ac1__1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]; activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]		activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]		basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]	
d3g04c__d3g3bc___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]; activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glycoprotein [GO:1904588]; cellular response to thyrotropin-releasing hormone [GO:1905229]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; thyroid-stimulating hormone signaling pathway [GO:0038194]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	G protein-coupled peptide receptor activity [GO:0008528]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; thyroid-stimulating hormone receptor activity [GO:0004996]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3g08b__d1rz8c2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3g08b__d4janb1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3g0bb2_d1ukba___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	hydrolase activity [GO:0016787]
d3g0bd2_d3a2ne___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	haloalkane dehalogenase activity [GO:0018786]; identical protein binding [GO:0042802]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	haloalkane dehalogenase activity [GO:0018786]; identical protein binding [GO:0042802]
d3g0cb2_d2xdwa2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d3g0cc2_d1nx9d2__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d3g0dc2_d2bjha___1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]; cell wall macromolecule catabolic process [GO:0016998]; cellulose catabolic process [GO:0030245]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellulose catabolic process [GO:0030245]; cell wall macromolecule catabolic process [GO:0016998]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]
d3g0ga2_d1xrra___1	Metazoa		Chordata	Euryarchaeota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	aminopeptidase activity [GO:0004177]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	aminopeptidase activity [GO:0004177]
d3g0ja__d4qbma1__1	Metazoa	Metazoa	Chordata	Chordata	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	chromatin silencing complex [GO:0005677]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; rDNA heterochromatin [GO:0033553]; histone binding [GO:0042393]; lysine-acetylated histone binding [GO:0070577]; metal ion binding [GO:0046872]; nuclear receptor binding [GO:0016922]; RNA binding [GO:0003723]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]; chromatin remodeling [GO:0006338]; chromatin silencing at rDNA [GO:0000183]; DNA methylation [GO:0006306]; histone deacetylation [GO:0016575]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	chromatin remodeling [GO:0006338]; chromatin silencing at rDNA [GO:0000183]; DNA methylation [GO:0006306]; histone deacetylation [GO:0016575]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]	chromatin silencing complex [GO:0005677]; cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; rDNA heterochromatin [GO:0033553]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]	histone binding [GO:0042393]; lysine-acetylated histone binding [GO:0070577]; metal ion binding [GO:0046872]; nuclear receptor binding [GO:0016922]; RNA binding [GO:0003723]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]
d3g0ja__d5fdzb___1	Metazoa	Metazoa	Chordata	Chordata	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]
d3g0ma__d5wkpd___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; iron-sulfur cluster assembly [GO:0016226]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cysteine desulfurase activity [GO:0031071]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; [2Fe-2S] cluster assembly [GO:0044571]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor biosynthetic process [GO:0032324]; small molecule metabolic process [GO:0044281]	iron-sulfur cluster assembly [GO:0016226]	[2Fe-2S] cluster assembly [GO:0044571]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; small molecule metabolic process [GO:0044281]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		cysteine desulfurase activity [GO:0031071]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]
d3g0qa1_d1lwva1__1		Metazoa	Firmicutes	Chordata	4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]		mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	4 iron, 4 sulfur cluster binding [GO:0051539]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; metal ion binding [GO:0046872]	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO:0034039]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; endonuclease activity [GO:0004519]; microtubule binding [GO:0008017]; oxidized purine DNA binding [GO:0032357]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]
d3g0va__d3ds2a___1					host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]; aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral procapsid maturation [GO:0046797]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral procapsid maturation [GO:0046797]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3g11a1_d1fj8b1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d3g11a1_d2x3ea1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d3g11a2_d1xplb2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]	isoprenoid biosynthetic process [GO:0008299]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d3g1ab__d1dqxd___1		Fungi	Euryarchaeota	Ascomycota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]		cytosol [GO:0005829]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3g1ba__d3gq1b___1			Proteobacteria	Proteobacteria	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]				
d3g1db__d2nv2k___1			Euryarchaeota	Firmicutes	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]; glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]		cytosol [GO:0005829]; glutaminase complex [GO:1903600]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3g1fb__d3lhwa___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3g1fc__d2ck9e___1			Euryarchaeota		orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]				orotidine-5'-phosphate decarboxylase activity [GO:0004590]	
d3g1fe__d1q6ra___1			Euryarchaeota	Proteobacteria	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3g1fg__d3exrd___1			Euryarchaeota	Firmicutes	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3g1fj__d4firc___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; pyridoxal phosphate biosynthetic process [GO:0042823]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal phosphate biosynthetic process [GO:0042823]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3g1hf__d4firf___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; pyridoxal phosphate biosynthetic process [GO:0042823]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal phosphate biosynthetic process [GO:0042823]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3g1hg__d2flic___1			Euryarchaeota	Firmicutes	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3g1hh__d1dqwc___1		Fungi	Euryarchaeota	Ascomycota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]		cytosol [GO:0005829]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3g1hh__d3feme___1		Fungi	Euryarchaeota	Ascomycota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]		glutaminase complex [GO:1903600]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3g1hi__d2cffa___1			Euryarchaeota	Thermotogae	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]; histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]
d3g1hj__d5lnsd___1		Viridiplantae	Euryarchaeota	Streptophyta	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]; amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]		cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3g1hk__d3gdra___1		Fungi	Euryarchaeota	Ascomycota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]		cytosol [GO:0005829]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3g1hk__d6bmaa1__1			Euryarchaeota	Proteobacteria	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	tryptophan biosynthetic process [GO:0000162]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	indole-3-glycerol-phosphate synthase activity [GO:0004425]
d3g1hl__d5lnvb___1		Viridiplantae	Euryarchaeota	Streptophyta	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]; amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]		cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3g1hm__d2nv2u___1			Euryarchaeota	Firmicutes	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]; glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]		cytosol [GO:0005829]; glutaminase complex [GO:1903600]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3g1hm__d3g1vb___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3g1la1_d2ld5a___1		Metazoa	Actinobacteria	Chordata	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; enhancer sequence-specific DNA binding [GO:0001158]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; anatomical structure morphogenesis [GO:0009653]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; branching involved in prostate gland morphogenesis [GO:0060442]; embryonic forelimb morphogenesis [GO:0035115]; endothelial cell fate specification [GO:0060847]; endothelial cell morphogenesis [GO:0001886]; inner ear development [GO:0048839]; male genitalia development [GO:0030539]; positive regulation of mesenchymal cell apoptotic process [GO:2001055]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of BMP signaling pathway [GO:0030510]; tissue homeostasis [GO:0001894]; vasculogenesis [GO:0001570]; ventricular septum development [GO:0003281]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	anatomical structure morphogenesis [GO:0009653]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; branching involved in prostate gland morphogenesis [GO:0060442]; embryonic forelimb morphogenesis [GO:0035115]; endothelial cell fate specification [GO:0060847]; endothelial cell morphogenesis [GO:0001886]; inner ear development [GO:0048839]; male genitalia development [GO:0030539]; positive regulation of mesenchymal cell apoptotic process [GO:2001055]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of BMP signaling pathway [GO:0030510]; tissue homeostasis [GO:0001894]; vasculogenesis [GO:0001570]; ventricular septum development [GO:0003281]	cytosol [GO:0005829]	cytosol [GO:0005829]; intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; enhancer sequence-specific DNA binding [GO:0001158]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]
d3g1ra__d3m4ha___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d3g22a__d3ovpa___1		Metazoa	Euryarchaeota	Chordata	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3g22a__d4o11a___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3g22b__d1lbfa___1			Euryarchaeota	Crenarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	tryptophan biosynthetic process [GO:0000162]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]
d3g24a__d5dn1a___1			Euryarchaeota	Actinobacteria	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]; phosphoribosylanthranilate isomerase activity [GO:0004640]; histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]; phosphoribosylanthranilate isomerase activity [GO:0004640]
d3g29b__d3g1gb___1					host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]; aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral procapsid maturation [GO:0046797]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]; aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral procapsid maturation [GO:0046797]	viral procapsid maturation [GO:0046797]	viral procapsid maturation [GO:0046797]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]	aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d3g2ca1_d1y21a___1		Metazoa	Euryarchaeota	Arthropoda	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	extracellular space [GO:0005615]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide transport [GO:0030185]; phosphatidylinositol dephosphorylation [GO:0046856]; vasodilation in other organism [GO:0044552]	DNA repair [GO:0006281]	nitric oxide transport [GO:0030185]; phosphatidylinositol dephosphorylation [GO:0046856]; vasodilation in other organism [GO:0044552]		extracellular space [GO:0005615]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3g2da__d2v0sa___1		Metazoa	Euryarchaeota	Chordata	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	metal ion binding [GO:0046872]; RNA-directed DNA polymerase activity [GO:0003964]; type II site-specific deoxyribonuclease activity [GO:0009036]; DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197]	DNA repair [GO:0006281]	DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197]			DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; RNA-directed DNA polymerase activity [GO:0003964]; type II site-specific deoxyribonuclease activity [GO:0009036]
d3g2db__d3g3ya1__1			Euryarchaeota	Euryarchaeota	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	DNA repair [GO:0006281]	DNA repair [GO:0006281]			DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d3g2sb__d1hg5a2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]; 1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]; axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]
d3g2tb__d1szab1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA polymerase II complex binding [GO:0000993]; mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; termination of RNA polymerase II transcription [GO:0006369]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; termination of RNA polymerase II transcription, poly(A)-coupled [GO:0030846]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; termination of RNA polymerase II transcription [GO:0006369]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; termination of RNA polymerase II transcription, poly(A)-coupled [GO:0030846]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	mRNA binding [GO:0003729]; RNA polymerase II complex binding [GO:0000993]
d3g2ub__d1lf8a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]; ADP-ribosylation factor binding [GO:0030306]; ubiquitin binding [GO:0043130]; cellular protein metabolic process [GO:0044267]; endocytic recycling [GO:0032456]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; negative regulation of amyloid-beta formation [GO:1902430]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein localization to cell surface [GO:0034394]; protein localization to lysosome [GO:0061462]; regulation of protein stability [GO:0031647]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	cellular protein metabolic process [GO:0044267]; endocytic recycling [GO:0032456]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; negative regulation of amyloid-beta formation [GO:1902430]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein localization to cell surface [GO:0034394]; protein localization to lysosome [GO:0061462]; regulation of protein stability [GO:0031647]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	ADP-ribosylation factor binding [GO:0030306]; ubiquitin binding [GO:0043130]
d3g2wa__d1sz9b1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA polymerase II complex binding [GO:0000993]; mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; termination of RNA polymerase II transcription [GO:0006369]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; termination of RNA polymerase II transcription, poly(A)-coupled [GO:0030846]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; termination of RNA polymerase II transcription [GO:0006369]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; termination of RNA polymerase II transcription, poly(A)-coupled [GO:0030846]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	mRNA binding [GO:0003729]; RNA polymerase II complex binding [GO:0000993]
d3g2wb__d5lp0a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]		cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]		cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]		ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]	
d3g2xe1_d3gpac1__1					ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3g3aa__d1o6va2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall [GO:0005618]; extracellular region [GO:0005576]; entry of bacterium into host cell [GO:0035635]; pathogenesis [GO:0009405]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	entry of bacterium into host cell [GO:0035635]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell wall [GO:0005618]; extracellular region [GO:0005576]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	
d3g3ac__d6b3se1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d3g3ba__d1ft8d___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d3g3bc__d1d0ba___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d3g3cb1_d2jc4a___1			Euryarchaeota	Proteobacteria	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; exodeoxyribonuclease III activity [GO:0008853]; DNA repair [GO:0006281]	DNA repair [GO:0006281]	DNA repair [GO:0006281]			DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; exodeoxyribonuclease III activity [GO:0008853]
d3g3cb1_d4lndb___1		Metazoa	Euryarchaeota	Chordata	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	DNA repair [GO:0006281]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]		cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]
d3g3fa__d1uiua___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]
d3g3ia__d1pc3a___1	Metazoa		Chordata	Actinobacteria	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; cell surface [GO:0009986]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; phosphate ion binding [GO:0042301]; cell adhesion [GO:0007155]; cellular response to phosphate starvation [GO:0016036]; pathogenesis [GO:0009405]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	cell adhesion [GO:0007155]; cellular response to phosphate starvation [GO:0016036]; pathogenesis [GO:0009405]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; cell surface [GO:0009986]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	phosphate ion binding [GO:0042301]
d3g3na__d1rkoc___1	Metazoa		Chordata		cytosol [GO:0005829]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; G protein-coupled receptor signaling pathway [GO:0007186]		cAMP catabolic process [GO:0006198]; G protein-coupled receptor signaling pathway [GO:0007186]		cytosol [GO:0005829]		3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]	
d3g3na__d2ousb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; G protein-coupled receptor signaling pathway [GO:0007186]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; G protein-coupled receptor signaling pathway [GO:0007186]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3g3pa__d2zjq51__1			Proteobacteria	Deinococcus-Thermus	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d3g3wa__d1ljha___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3g3ya1_d1de8b___1		Metazoa	Euryarchaeota	Chordata	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	DNA repair [GO:0006281]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]		cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]
d3g3yb__d1dewa___1		Metazoa	Euryarchaeota	Chordata	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	DNA repair [GO:0006281]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]		cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]
d3g41a__d4o8mh___1				Proteobacteria		outer membrane-bounded periplasmic space [GO:0030288]; transmembrane transport [GO:0055085]		transmembrane transport [GO:0055085]		outer membrane-bounded periplasmic space [GO:0030288]		
d3g42a__d3kmcb___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d3g42a__d4ja1a___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3g42c__d2mlsa___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3g43a__d5cpva___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	calcium ion binding [GO:0005509]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]		adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]
d3g46a__d2uulv___1	Metazoa		Mollusca		cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3g49a__d4afna1__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; lung development [GO:0030324]; steroid metabolic process [GO:0008202]	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]	lung development [GO:0030324]; steroid metabolic process [GO:0008202]	fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3g4ib__d5u00c1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d3g4kc__d3hqza___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]
d3g4kd__d4e90b1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3g4lb__d3dynb2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3g4lb__d4mrwa1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3g4oa1_d3paka2__1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]		cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	identical protein binding [GO:0042802]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]
d3g4qa__d5d1va___1	Metazoa		Mollusca	Chloroflexi	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; thioredoxin peroxidase activity [GO:0008379]
d3g4qb__d3s1jc___1	Metazoa		Mollusca	Verrucomicrobia	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3g4rb__d3h57a___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3g4vb__d1j3ye___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3g4vb__d2uumk___1	Metazoa		Mollusca	Cyanobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3g4wa__d2bv8o___1	Metazoa		Mollusca	Rhodophyta	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3g4xa__d1t6qc___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d3g4xb__d3g50c___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d3g4ya__d1hv4e___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3g4za__d1t6ul___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d3g4zc__d1t6uh___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]	nickel cation binding [GO:0016151]; superoxide dismutase activity [GO:0004784]
d3g52b__d3qjda___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3g53b__d1yhua___1	Metazoa	Metazoa	Mollusca	Annelida	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3g5ea__d3b3db___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	oxidoreductase activity [GO:0016491]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	oxidoreductase activity [GO:0016491]
d3g5gb__d2ivge1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]		cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d3g5gd__d4i6ua___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]	DNA binding [GO:0003677]					DNA binding [GO:0003677]	DNA binding [GO:0003677]
d3g5gi__d2bnna1__1			Proteobacteria	Actinobacteria	DNA binding [GO:0003677]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]			DNA binding [GO:0003677]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d3g5gk__d1zz6b1__1			Proteobacteria	Actinobacteria	DNA binding [GO:0003677]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]			DNA binding [GO:0003677]	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]
d3g5gl__d2iv1g1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]	cytoplasm [GO:0005737]; cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]; cyanate catabolic process [GO:0009440]		cyanate catabolic process [GO:0009440]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]	cyanate hydratase activity [GO:0008824]; DNA binding [GO:0003677]
d3g5ha__d3fwgb___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3g5ka1_d1zxza1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; positive regulation of cell population proliferation [GO:0008284]; translation [GO:0006412]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; mitochondrion [GO:0005739]; plant-type cell wall [GO:0009505]; metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; co-translational protein modification [GO:0043686]; translation [GO:0006412]	N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; positive regulation of cell population proliferation [GO:0008284]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; translation [GO:0006412]	mitochondrion [GO:0005739]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; mitochondrion [GO:0005739]; plant-type cell wall [GO:0009505]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d3g5kd1_d1bs5c___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; positive regulation of cell population proliferation [GO:0008284]; translation [GO:0006412]	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; positive regulation of cell population proliferation [GO:0008284]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	mitochondrion [GO:0005739]	cytosol [GO:0005829]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]	ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]
d3g5pa1_d4dr8a___1	Metazoa		Chordata	Cyanobacteria	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; positive regulation of cell population proliferation [GO:0008284]; translation [GO:0006412]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; translation [GO:0006412]	N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; positive regulation of cell population proliferation [GO:0008284]; translation [GO:0006412]	translation [GO:0006412]	mitochondrion [GO:0005739]		metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d3g5pb1_d4al2a___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; positive regulation of cell population proliferation [GO:0008284]; translation [GO:0006412]	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; positive regulation of cell population proliferation [GO:0008284]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	mitochondrion [GO:0005739]	cytosol [GO:0005829]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]	ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]
d3g5xa2_d4pj7f1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3g5xc1_d3qa3a1__1		Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]
d3g5za1_d1bx2d1__1		Metazoa		Chordata		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d3g63a1_d2gfeb1__1		Metazoa		Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3g6aa1_d1blnb1__1												
d3g6aa1_d3sgei1__1												
d3g6aa2_d1waaf___1		Metazoa		Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d3g6ab1_d4fqqe1__1		Metazoa		Chordata								
d3g6ab1_d4l8cb___1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3g6al1_d1rzjh1__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3g6da__d1hmca___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	CSF1-CSF1R complex [GO:1990682]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nuclear body [GO:0016604]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; macrophage colony-stimulating factor receptor binding [GO:0005157]; protein homodimerization activity [GO:0042803]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; developmental process involved in reproduction [GO:0003006]; hemopoiesis [GO:0030097]; homeostasis of number of cells within a tissue [GO:0048873]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage colony-stimulating factor signaling pathway [GO:0038145]; macrophage differentiation [GO:0030225]; mammary duct terminal end bud growth [GO:0060763]; mammary gland fat development [GO:0060611]; microglial cell proliferation [GO:0061518]; monocyte activation [GO:0042117]; negative regulation of neuron death [GO:1901215]; osteoclast differentiation [GO:0030316]; osteoclast proliferation [GO:0002158]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage colony-stimulating factor signaling pathway [GO:1902228]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of odontogenesis of dentin-containing tooth [GO:0042488]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of Ras protein signal transduction [GO:0046579]; post-translational protein modification [GO:0043687]; regulation of macrophage derived foam cell differentiation [GO:0010743]; regulation of ossification [GO:0030278]; response to ischemia [GO:0002931]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	branching involved in mammary gland duct morphogenesis [GO:0060444]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; developmental process involved in reproduction [GO:0003006]; hemopoiesis [GO:0030097]; homeostasis of number of cells within a tissue [GO:0048873]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage colony-stimulating factor signaling pathway [GO:0038145]; macrophage differentiation [GO:0030225]; mammary duct terminal end bud growth [GO:0060763]; mammary gland fat development [GO:0060611]; microglial cell proliferation [GO:0061518]; monocyte activation [GO:0042117]; negative regulation of neuron death [GO:1901215]; osteoclast differentiation [GO:0030316]; osteoclast proliferation [GO:0002158]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage colony-stimulating factor signaling pathway [GO:1902228]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of microglial cell migration [GO:1904141]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of mononuclear cell proliferation [GO:0032946]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of odontogenesis of dentin-containing tooth [GO:0042488]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of Ras protein signal transduction [GO:0046579]; post-translational protein modification [GO:0043687]; regulation of macrophage derived foam cell differentiation [GO:0010743]; regulation of ossification [GO:0030278]; response to ischemia [GO:0002931]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	CSF1-CSF1R complex [GO:1990682]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nuclear body [GO:0016604]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; macrophage colony-stimulating factor receptor binding [GO:0005157]; protein homodimerization activity [GO:0042803]
d3g6dh2_d1hngb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; protein-containing complex [GO:0032991]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of tumor necrosis factor production [GO:0032760]; T cell activation [GO:0042110]	cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	cell-cell adhesion [GO:0098609]; heterotypic cell-cell adhesion [GO:0034113]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of tumor necrosis factor production [GO:0032760]; T cell activation [GO:0042110]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; protein-containing complex [GO:0032991]	cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]	protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]
d3g6dh2_d1q94b1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3g6dl1_d1j89b1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	Fc-epsilon receptor signaling pathway [GO:0038095]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]	IgE binding [GO:0019863]
d3g6dl2_d1zglg1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3g6jg1_d3qxta___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]		amyloid-beta clearance [GO:0097242]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cellular protein metabolic process [GO:0044267]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; complement-dependent cytotoxicity [GO:0097278]; complement-mediated synapse pruning [GO:0150062]; fatty acid metabolic process [GO:0006631]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; neuron remodeling [GO:0016322]; neutrophil degranulation [GO:0043312]; positive regulation of activation of membrane attack complex [GO:0001970]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of glucose transmembrane transport [GO:0010828]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of type IIa hypersensitivity [GO:0001798]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of triglyceride biosynthetic process [GO:0010866]; response to bacterium [GO:0009617]; signal transduction [GO:0007165]; vertebrate eye-specific patterning [GO:0150064]		azurophil granule lumen [GO:0035578]; blood microparticle [GO:0072562]; cell surface [GO:0009986]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]		C5L2 anaphylatoxin chemotactic receptor binding [GO:0031715]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]	
d3g6oa1_d2gj3a___1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	ATP binding [GO:0005524]; protein histidine kinase activity [GO:0004673]
d3g6ob1_d5f5ya___1		Metazoa	Proteobacteria	Arthropoda	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]; behavioral response to cocaine [GO:0048148]; circadian regulation of gene expression [GO:0032922]; circadian regulation of heart rate [GO:0003053]; circadian rhythm [GO:0007623]; eclosion rhythm [GO:0008062]; locomotor rhythm [GO:0045475]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; response to starvation [GO:0042594]; rhythmic behavior [GO:0007622]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	behavioral response to cocaine [GO:0048148]; circadian regulation of gene expression [GO:0032922]; circadian regulation of heart rate [GO:0003053]; circadian rhythm [GO:0007623]; eclosion rhythm [GO:0008062]; locomotor rhythm [GO:0045475]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; response to starvation [GO:0042594]; rhythmic behavior [GO:0007622]		cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]
d3g6ob2_d1mc0a2__1		Metazoa	Proteobacteria	Chordata	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber [GO:0097457]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic membrane [GO:0097060]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; GAF domain binding [GO:0036004]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cardiac septum development [GO:0003279]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; coronary vasculature development [GO:0060976]; establishment of endothelial barrier [GO:0061028]; heart development [GO:0007507]; heart valve development [GO:0003170]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cell death [GO:0060548]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; regulation of nitric oxide mediated signal transduction [GO:0010749]; ventricular septum development [GO:0003281]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cardiac septum development [GO:0003279]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; coronary vasculature development [GO:0060976]; establishment of endothelial barrier [GO:0061028]; heart development [GO:0007507]; heart valve development [GO:0003170]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cell death [GO:0060548]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; regulation of nitric oxide mediated signal transduction [GO:0010749]; ventricular septum development [GO:0003281]		axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; hippocampal mossy fiber [GO:0097457]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic membrane [GO:0097060]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; GAF domain binding [GO:0036004]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d3g6wd__d3dahc1__1			Crenarchaeota	Proteobacteria	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]		cytoplasm [GO:0005737]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]
d3g75a__d4ce3a___1		Fungi	Firmicutes	Ascomycota	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]
d3g7ja2_d1gtuc1__1	Metazoa	Metazoa	Arthropoda	Chordata	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	transferase activity [GO:0016740]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d3g7ja2_d4q5fd2__1	Metazoa	Metazoa	Arthropoda	Nematoda (roundworms)	transferase activity [GO:0016740]	brush border [GO:0005903]; cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; cellular oxidant detoxification [GO:0098869]; oxidation-reduction process [GO:0055114]		cellular oxidant detoxification [GO:0098869]; oxidation-reduction process [GO:0055114]		brush border [GO:0005903]; cytoplasm [GO:0005737]	transferase activity [GO:0016740]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]
d3g7jb2_d3o76a2__1	Metazoa	Metazoa	Arthropoda	Chordata	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	transferase activity [GO:0016740]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]
d3g7ka1_d5k87a1__1			Firmicutes	Proteobacteria	methylitaconate delta-isomerase activity [GO:0050100]; cofactor catabolic process [GO:0051187]	intramolecular oxidoreductase activity, transposing C=C bonds [GO:0016863]; propionate catabolic process, 2-methylcitrate cycle [GO:0019629]	cofactor catabolic process [GO:0051187]	propionate catabolic process, 2-methylcitrate cycle [GO:0019629]			methylitaconate delta-isomerase activity [GO:0050100]	intramolecular oxidoreductase activity, transposing C=C bonds [GO:0016863]
d3g7ka2_d3ejxe2__1		Viridiplantae	Firmicutes	Streptophyta	methylitaconate delta-isomerase activity [GO:0050100]; cofactor catabolic process [GO:0051187]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; diaminopimelate epimerase activity [GO:0008837]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cofactor catabolic process [GO:0051187]	lysine biosynthetic process via diaminopimelate [GO:0009089]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]	methylitaconate delta-isomerase activity [GO:0050100]	diaminopimelate epimerase activity [GO:0008837]
d3g7kc1_d1u1wa2__1			Firmicutes	Proteobacteria	methylitaconate delta-isomerase activity [GO:0050100]; cofactor catabolic process [GO:0051187]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]	cofactor catabolic process [GO:0051187]	pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]			methylitaconate delta-isomerase activity [GO:0050100]	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity [GO:0102943]
d3g81c1_d4dn8a1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen trimer [GO:0005581]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; developmental process [GO:0032502]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	developmental process [GO:0032502]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	collagen trimer [GO:0005581]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d3g83a1_d2yhfc___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]; cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]
d3g83c1_d1kx0a1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d3g83c1_d2yhfh___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]; cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cellular defense response [GO:0006968]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; osteoblast development [GO:0002076]; positive regulation of cytokine secretion [GO:0050715]; signal transduction [GO:0007165]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	cell surface [GO:0009986]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; virus receptor activity [GO:0001618]
d3g84a1_d1msbb___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d3g8ca1_d1w96a2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d3g8ca2_d3vpda2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]
d3g8ca3_d1ez1b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d3g8cb1_d2dzda1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d3g8da1_d1c30a3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d3g8da2_d4mv8a3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d3g8ha__d1owsa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; host cell cytosol [GO:0044164]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; host cell cytosol [GO:0044164]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]
d3g8kb__d4kzwa___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]	integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; pattern recognition receptor activity [GO:0038187]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway [GO:0038094]; innate immune response [GO:0045087]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cytokine secretion [GO:0050715]; T cell differentiation involved in immune response [GO:0002292]		defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway [GO:0038094]; innate immune response [GO:0045087]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cytokine secretion [GO:0050715]; T cell differentiation involved in immune response [GO:0002292]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; pattern recognition receptor activity [GO:0038187]
d3g91a1_d2ddsc___1			Euryarchaeota	Firmicutes	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	extracellular region [GO:0005576]; sphingomyelin phosphodiesterase activity [GO:0004767]; hemolysis in other organism [GO:0044179]	DNA repair [GO:0006281]	hemolysis in other organism [GO:0044179]		extracellular region [GO:0005576]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	sphingomyelin phosphodiesterase activity [GO:0004767]
d3g9ab1_d5g5xb1__1	Metazoa		Cnidaria	Euryarchaeota	bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3g9ca__d3u1la2__1	Metazoa	Fungi	Chordata	Ascomycota	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	Prp19 complex [GO:0000974]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]; metal ion binding [GO:0046872]; pre-mRNA binding [GO:0036002]; U6 snRNA binding [GO:0017070]; cell cycle [GO:0007049]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cell cycle [GO:0045787]; positive regulation of RNA splicing [GO:0033120]; spliceosomal snRNP assembly [GO:0000387]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cell cycle [GO:0007049]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cell cycle [GO:0045787]; positive regulation of RNA splicing [GO:0033120]; spliceosomal snRNP assembly [GO:0000387]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	Prp19 complex [GO:0000974]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	metal ion binding [GO:0046872]; pre-mRNA binding [GO:0036002]; U6 snRNA binding [GO:0017070]
d3g9wa1_d1mizb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]; actin filament binding [GO:0051015]; structural constituent of cytoskeleton [GO:0005200]; cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	actin filament binding [GO:0051015]; structural constituent of cytoskeleton [GO:0005200]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]
d3g9wb1_d1h4rb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]; actin filament binding [GO:0051015]; structural constituent of cytoskeleton [GO:0005200]; cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016]	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	actin filament binding [GO:0051015]; structural constituent of cytoskeleton [GO:0005200]	actin binding [GO:0003779]
d3g9wb2_d1t77d2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]; actin filament binding [GO:0051015]; structural constituent of cytoskeleton [GO:0005200]; cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; fascia adherens [GO:0005916]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; membrane [GO:0016020]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; structural constituent of cytoskeleton [GO:0005200]	
d3g9xa1_d4a16b1__1		Metazoa	Actinobacteria	Chordata	haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]; acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	response to toxic substance [GO:0009636]	acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]		anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]	haloalkane dehalogenase activity [GO:0018786]	acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]
d3ga5a__d5dkvc___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; metal ion binding [GO:0046872]; carbohydrate transport [GO:0008643]; chemotaxis [GO:0006935]		carbohydrate transport [GO:0008643]; chemotaxis [GO:0006935]		outer membrane-bounded periplasmic space [GO:0030288]		metal ion binding [GO:0046872]	
d3ga5b__d3kg2b1__1		Metazoa	Proteobacteria	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; metal ion binding [GO:0046872]; carbohydrate transport [GO:0008643]; chemotaxis [GO:0006935]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; chemotaxis [GO:0006935]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3gaca__d3hofa1__1		Metazoa	Apicomplexa	Chordata		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d3gacd__d1mifa___1		Metazoa	Apicomplexa	Chordata		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d3gadb__d4lhpe___1			Apicomplexa	Actinobacteria								
d3gade1_d3rf5c___1		Metazoa	Apicomplexa	Nematoda (roundworms)		cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]						cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]
d3gadf1_d4xx7c___1		Metazoa	Apicomplexa	Chordata		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d3gama__d1e5da1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; respiratory electron transport chain [GO:0022904]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	respiratory electron transport chain [GO:0022904]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d3gaqa1_d1x71a___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; amine binding [GO:0043176]; evasion or tolerance of host defense response [GO:0030682]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	evasion or tolerance of host defense response [GO:0030682]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	amine binding [GO:0043176]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d3gb7a1_d1uz6f1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	voltage-gated potassium channel complex [GO:0008076]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3gb7a2_d4yhib1__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d3gb7b1_d5nsga2__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d3gbab1_d4ln5a___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	
d3gbba__d3m3la___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3gbbb1_d1ftob___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3gbda2_d3vgea3__1			Proteobacteria	Crenarchaeota	isomaltulose synthase activity [GO:0050006]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]		cytoplasm [GO:0005737]	isomaltulose synthase activity [GO:0050006]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]
d3gbea2_d3edda3__1			Proteobacteria	Bacteroidetes	isomaltulose synthase activity [GO:0050006]; carbohydrate metabolic process [GO:0005975]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			isomaltulose synthase activity [GO:0050006]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d3gbkb__d5ntnd___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]; activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d3gbla__d5nstc2__1	Metazoa		Chordata		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]			
d3gbma1_d1rd8c1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]	host cell surface receptor binding [GO:0046789]
d3gbmc1_d4kpsc1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]	host cell surface receptor binding [GO:0046789]
d3gbml2_d3cdyb___1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d3gboa__d3aiga___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3gbra1_d5ey3b1__1			Crenarchaeota	Proteobacteria	cytosol [GO:0005829]; anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]; tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]; phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]; pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]	tryptophan biosynthetic process [GO:0000162]	pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]	cytosol [GO:0005829]	cytosol [GO:0005829]	anthranilate phosphoribosyltransferase activity [GO:0004048]; magnesium ion binding [GO:0000287]	phosphorylase activity [GO:0004645]; pyrimidine-nucleoside phosphorylase activity [GO:0016154]; thymidine phosphorylase activity [GO:0009032]
d3gbsa__d1qe8a___1	Fungi		Ascomycota		extracellular region [GO:0005576]; cutinase activity [GO:0050525]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]		cutinase activity [GO:0050525]	
d3gc6a__d3zwoa___1	Metazoa	Metazoa	Chordata	Mollusca	plasma membrane [GO:0005886]; NAD glycohydrolase activity [GO:0061810]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]; metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	single fertilization [GO:0007338]	plasma membrane [GO:0005886]	cytoplasmic vesicle [GO:0031410]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD glycohydrolase activity [GO:0061810]; phosphorus-oxygen lyase activity [GO:0016849]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]
d3gcea__d4p1bi___1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]		toluene catabolic process [GO:0042203]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d3gcfa1_d2bmoa1__1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; cellular metabolic process [GO:0044237]		cellular metabolic process [GO:0044237]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3gcfa1_d4aayh___1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]					2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]
d3gcfa2_d4mnsa___1		Viridiplantae	Actinobacteria	Streptophyta	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d3gcfb1_d2i7fa___1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3gcfb2_d2de6c2__1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]		carbazole catabolic process [GO:0046232]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]
d3gcfe1_d1bcce1__1		Metazoa	Actinobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3gcfe2_d2le1a1__1			Actinobacteria	Actinobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]						2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	
d3gcfg1_d1o7ha1__1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]
d3gcfh1_d1l0ne1__1		Metazoa	Actinobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3gcfh2_d5xbpd2__1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]		cellular metabolic process [GO:0044237]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]
d3gcfi1_d1l0le1__1		Metazoa	Actinobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3gcfj1_d2de6a1__1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]; carbazole catabolic process [GO:0046232]		carbazole catabolic process [GO:0046232]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; ferredoxin hydrogenase activity [GO:0008901]; metal ion binding [GO:0046872]
d3gcfl1_d1vm9a___1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; toluene catabolic process [GO:0042203]		toluene catabolic process [GO:0042203]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d3gcfl2_d1icxa___1		Viridiplantae	Actinobacteria	Streptophyta	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]		abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]; RNA phosphodiester bond hydrolysis [GO:0090501]		cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	abscisic acid binding [GO:0010427]; calcium ion binding [GO:0005509]; cytokinin binding [GO:0044373]; melatonin binding [GO:1904408]; protein phosphatase inhibitor activity [GO:0004864]; ribonuclease activity [GO:0004540]; signaling receptor activity [GO:0038023]
d3gcfm1_d2gbwc1__1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; cellular aromatic compound metabolic process [GO:0006725]		cellular aromatic compound metabolic process [GO:0006725]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]
d3gcfn2_d1o7pa2__1			Actinobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]
d3gcha__d2a7ca___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3gcia__d1owsb___1	Metazoa	Metazoa	Chordata	Chordata	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid-beta clearance [GO:1900221]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi lumen [GO:0005796]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]	extracellular region [GO:0005576]	acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]
d3gcza__d1rjfa1__1		Fungi		Ascomycota	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; C-terminal protein methylation [GO:0006481]; cellular protein-containing complex assembly [GO:0034622]; regulation of autophagy [GO:0010506]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cellular protein-containing complex assembly [GO:0034622]; C-terminal protein methylation [GO:0006481]; regulation of autophagy [GO:0010506]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]
d3gd6a1_d2fyma2__1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3gd6a2_d3ozmg2__1			Firmicutes	Proteobacteria	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]		cellular amino acid catabolic process [GO:0009063]			lyase activity [GO:0016829]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3gdfb__d2uyya1__1	Fungi	Metazoa	Ascomycota	Chordata	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]	mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]		cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491]
d3gdga__d2rh4b2__1	Fungi		Ascomycota	Actinobacteria	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]	mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	antibiotic biosynthetic process [GO:0017000]			mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]	oxidoreductase activity [GO:0016491]
d3gdgb__d4ei2g1__1	Fungi		Ascomycota	Euryarchaeota	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	potassium ion transport [GO:0006813]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3gdgc__d1qyda___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	lariciresinol reductase activity [GO:0010284]; pinoresinol reductase activity [GO:0010283]; (+)-lariciresinol biosynthetic process [GO:1902132]; (+)-pinoresinol catabolic process [GO:1902125]; (+)-secoisolariciresinol biosynthetic process [GO:1902135]; (-)-lariciresinol biosynthetic process [GO:1902129]; (-)-lariciresinol catabolic process [GO:1902128]; (-)-pinoresinol catabolic process [GO:1902123]; lignan biosynthetic process [GO:0009807]	mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	(-)-lariciresinol biosynthetic process [GO:1902129]; (-)-lariciresinol catabolic process [GO:1902128]; (-)-pinoresinol catabolic process [GO:1902123]; (+)-lariciresinol biosynthetic process [GO:1902132]; (+)-pinoresinol catabolic process [GO:1902125]; (+)-secoisolariciresinol biosynthetic process [GO:1902135]; lignan biosynthetic process [GO:0009807]			mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]	lariciresinol reductase activity [GO:0010284]; pinoresinol reductase activity [GO:0010283]
d3gdgd__d2ie0a___1	Fungi		Ascomycota	Actinobacteria	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	mannitol metabolic process [GO:0019594]; protein homotetramerization [GO:0051289]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]	mannitol 2-dehydrogenase (NADP+) activity [GO:0050085]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d3gdjb__d1f99m___1	Metazoa		Chordata	Rhodophyta	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3gdka__d1vc4a___1	Fungi		Ascomycota	Deinococcus-Thermus	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]		orotidine-5'-phosphate decarboxylase activity [GO:0004590]	indole-3-glycerol-phosphate synthase activity [GO:0004425]
d3gdlb__d1dvjd___1	Fungi		Ascomycota	Euryarchaeota	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]		orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3gdqa1_d3ldpb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; zona pellucida receptor complex [GO:0002199]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; binding of sperm to zona pellucida [GO:0007339]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein refolding [GO:0042026]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	binding of sperm to zona pellucida [GO:0007339]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein refolding [GO:0042026]; regulation of cellular response to heat [GO:1900034]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	blood microparticle [GO:0072562]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; zona pellucida receptor complex [GO:0002199]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3gdtb__d3tsmb___1	Fungi		Ascomycota	Proteobacteria	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	tryptophan biosynthetic process [GO:0000162]	cytosol [GO:0005829]		orotidine-5'-phosphate decarboxylase activity [GO:0004590]	indole-3-glycerol-phosphate synthase activity [GO:0004425]
d3ge3a__d3bvfc1__1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	toluene catabolic process [GO:0042203]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d3ge4a__d5d8pj___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3ge4c__d2fjck___1			Proteobacteria	Spirochaetes	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3ge4e__d4xgsa1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cellular iron ion homeostasis [GO:0006879]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3ge4f__d3wnwe___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cellular iron ion homeostasis [GO:0006879]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3ge4k__d3qd8h1__1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3ge4l__d1s30a1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cytoplasm [GO:0005737]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]	cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3ge8a__d2bkcp___1			Proteobacteria	Firmicutes	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	toluene catabolic process [GO:0042203]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3ge8d__d3is7j___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	toluene catabolic process [GO:0042203]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3gfqa__d1czra___1			Firmicutes	Cyanobacteria	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]			cytosol [GO:0005829]		FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3gfra__d1rtta___1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; protein homodimerization activity [GO:0042803]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]	cytosol [GO:0005829]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; protein homodimerization activity [GO:0042803]
d3gfrb__d1h69a___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3gfrd__d4u7ha___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d3gfsc__d2d5ia___1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; azobenzene reductase activity [GO:0050446]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor [GO:0016652]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; response to oxidative stress [GO:0006979]		response to oxidative stress [GO:0006979]	cytosol [GO:0005829]	cytosol [GO:0005829]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	azobenzene reductase activity [GO:0050446]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor [GO:0016652]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]
d3gfsf__d3esyc___1			Firmicutes	Cyanobacteria	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]		cellular response to iron ion starvation [GO:0010106]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]	cell [GO:0005623]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3gfsg__d1f4pa___1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]			cytosol [GO:0005829]		FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3gfsg__d3gfqa___1			Firmicutes	Firmicutes	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]			cytosol [GO:0005829]	cytosol [GO:0005829]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d3gfsh__d5eaii___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3gfsj__d1qr2a___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d3gfsj__d2fzvb2__1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	azobenzene reductase activity [GO:0050446]; FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]		oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]		FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	azobenzene reductase activity [GO:0050446]; FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]
d3gfsl__d2qr2a___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d3gg5d__d5h39b___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]		cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	thymidylate synthase activity [GO:0004799]
d3gg7a1_d4lefd___1			Deinococcus-Thermus	Proteobacteria	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; zinc ion binding [GO:0008270]; catabolic process [GO:0009056]		catabolic process [GO:0009056]			hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; zinc ion binding [GO:0008270]
d3ggab__d5oyxa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ggac__d1axab___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ggac__d4y6mc___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ggad__d3qpjb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ggsa__d1jpva___1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; nucleoside metabolic process [GO:0009116]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]		drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]	S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]
d3ggta__d3h5ba___1						host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ggva__d5p8ga___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ggvd__d5p82a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ggve__d4y5aa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ggvf__d3lzsa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ggvh__d2pk5a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ggxa__d1fiva___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d3ggxa__d2er6e___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ggxb__d5p4da___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ggxc__d1kj4c___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ggxc__d5p6ra___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ggxd__d4y54a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ggxe__d2i4db___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ggxe__d5p4na___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ggxg__d5p47a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3gh3b__d5bnib___1	Metazoa	Metazoa	Chordata	Chordata	plasma membrane [GO:0005886]; NAD glycohydrolase activity [GO:0061810]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]; metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]; positive regulation of B cell proliferation [GO:0030890]	metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	positive regulation of B cell proliferation [GO:0030890]	plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD glycohydrolase activity [GO:0061810]; phosphorus-oxygen lyase activity [GO:0016849]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]
d3gh6a1_d1iyhc2__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione metabolic process [GO:0006749]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	glutathione transferase activity [GO:0004364]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d3ghqa__d1mhyb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	methane monooxygenase activity [GO:0015049]; methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	methane monooxygenase activity [GO:0015049]
d3ghqj__d1fz8d___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3ghqk__d2iy4p___1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3ghqk__d3oj5p___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d3ghql__d1veqd___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3ghql__d2chpd___1			Proteobacteria	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3ghwa__d4g3md2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d3gi2a__d3frex___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3gi5a__d1gnob___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3gi6b__d5p8pa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3gi9l2_d4k2ul1__1			Euryarchaeota	Apicomplexa	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; transmembrane transporter activity [GO:0022857]	integral component of membrane [GO:0016021]; microneme [GO:0020009]; heparin binding [GO:0008201]; host cell surface receptor binding [GO:0046789]; entry into host cell [GO:0030260]; pathogenesis [GO:0009405]		entry into host cell [GO:0030260]; pathogenesis [GO:0009405]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; microneme [GO:0020009]	transmembrane transporter activity [GO:0022857]	heparin binding [GO:0008201]; host cell surface receptor binding [GO:0046789]
d3giba__d4mmkd___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; bent DNA binding [GO:0003681]; RNA binding [GO:0003723]; negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]	cytosol [GO:0005829]	bent DNA binding [GO:0003681]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3giqb2_d4lefc___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; N-acyl-D-glutamate deacylase activity [GO:0047421]	hydrolase activity, acting on ester bonds [GO:0016788]; zinc ion binding [GO:0008270]; catabolic process [GO:0009056]		catabolic process [GO:0009056]			metal ion binding [GO:0046872]; N-acyl-D-glutamate deacylase activity [GO:0047421]	hydrolase activity, acting on ester bonds [GO:0016788]; zinc ion binding [GO:0008270]
d3givb1_d2fx8i2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d3give1_d1i9jl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3gizl1_d3l7ea1__1												
d3gizl2_d5u16f1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3gj4a__d2oljb1__1	Metazoa		Chordata	Firmicutes	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]		centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]		androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	ATPase activity [GO:0016887]; ATPase-coupled amino acid transmembrane transporter activity [GO:0015424]; ATP binding [GO:0005524]
d3gj4a__d3vhxg1__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cell [GO:0005623]; centralspindlin complex [GO:0097149]; centrosome [GO:0005813]; cytosol [GO:0005829]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; intercellular bridge [GO:0045171]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	cell [GO:0005623]; centralspindlin complex [GO:0097149]; centrosome [GO:0005813]; cytosol [GO:0005829]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; intercellular bridge [GO:0045171]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]
d3gj4c__d2lkda1__1	Metazoa		Chordata	Firmicutes	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation initiation factor activity [GO:0003743]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]		centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	cytoplasm [GO:0005737]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation initiation factor activity [GO:0003743]
d3gj6a__d3rvba2__1	Metazoa		Chordata		centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3gj7a__d2cnwa2__1	Metazoa		Chordata	Deinococcus-Thermus	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	signal recognition particle [GO:0048500]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d3gj8a__d1z83b1__1	Metazoa	Metazoa	Chordata	Chordata	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3gj8c__d1g8fa3__1	Metazoa	Fungi	Chordata	Ascomycota	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d3gjea2_d4pjcf1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3gjel1_d4yhib2__1												
d3gjel2_d5bzda2__1												
d3gjfb1_d3whxb1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3gjfe1_d5wlgj2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3gk1a__d1xk4f___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d3gk8l1_d3p4nb___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3gk8l2_d2ibzy___1		Fungi		Ascomycota		integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]		
d3gkaa__d2djxb___1			Proteobacteria		FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d3gkab1_d3w85b___1			Proteobacteria		FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d3gklc__d4qkoe___1			Proteobacteria	Proteobacteria	extrachromosomal circular DNA [GO:0005727]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	extrachromosomal circular DNA [GO:0005727]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; signaling receptor binding [GO:0005102]
d3gkvb__d5o18a___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]		apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]	hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3gkwl1_d1h9va2__1		Metazoa		Chordata		Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]		Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]		Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]		IgG binding [GO:0019864]
d3gl1a2_d5aqya1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; polysome [GO:0005844]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; calmodulin binding [GO:0005516]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; 'de novo' cotranslational protein folding [GO:0051083]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; cytoplasmic translation [GO:0002181]; protein refolding [GO:0042026]; regulation of translational fidelity [GO:0006450]; response to unfolded protein [GO:0006986]; ribosomal subunit export from nucleus [GO:0000054]; rRNA processing [GO:0006364]; translational frameshifting [GO:0006452]; translational termination [GO:0006415]; vesicle-mediated transport [GO:0016192]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	'de novo' cotranslational protein folding [GO:0051083]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; cytoplasmic translation [GO:0002181]; protein refolding [GO:0042026]; regulation of translational fidelity [GO:0006450]; response to unfolded protein [GO:0006986]; ribosomal subunit export from nucleus [GO:0000054]; rRNA processing [GO:0006364]; translational frameshifting [GO:0006452]; translational termination [GO:0006415]; vesicle-mediated transport [GO:0016192]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; polysome [GO:0005844]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]
d3glaa__d2h50r1__1		Viridiplantae	Proteobacteria	Streptophyta		cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]		protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]
d3glja1_d1pbaa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d3glja2_d1iy7a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d3gm0a2_d1sysa1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3gm1a__d2lk4a___1	Metazoa	Metazoa	Chordata	Chordata	apical dendrite [GO:0097440]; cell [GO:0005623]; cell body [GO:0044297]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase binding [GO:0043423]; ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; NMDA glutamate receptor activity [GO:0004972]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein C-terminus binding [GO:0008022]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; ubiquitin protein ligase binding [GO:0031625]; activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-containing complex assembly [GO:0065003]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of NMDA receptor activity [GO:2000310]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of synaptic plasticity [GO:0048167]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	apical dendrite [GO:0097440]; cell [GO:0005623]; cell body [GO:0044297]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase binding [GO:0043423]; ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; NMDA glutamate receptor activity [GO:0004972]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein C-terminus binding [GO:0008022]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; ubiquitin protein ligase binding [GO:0031625]; activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-containing complex assembly [GO:0065003]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of NMDA receptor activity [GO:2000310]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of synaptic plasticity [GO:0048167]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; protein-containing complex assembly [GO:0065003]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of NMDA receptor activity [GO:2000310]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of synaptic plasticity [GO:0048167]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; protein-containing complex assembly [GO:0065003]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of NMDA receptor activity [GO:2000310]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of synaptic plasticity [GO:0048167]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	apical dendrite [GO:0097440]; cell [GO:0005623]; cell body [GO:0044297]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]	apical dendrite [GO:0097440]; cell [GO:0005623]; cell body [GO:0044297]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]	3-phosphoinositide-dependent protein kinase binding [GO:0043423]; ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; NMDA glutamate receptor activity [GO:0004972]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein tyrosine kinase activity [GO:0004713]; ubiquitin protein ligase binding [GO:0031625]	3-phosphoinositide-dependent protein kinase binding [GO:0043423]; ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; NMDA glutamate receptor activity [GO:0004972]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein tyrosine kinase activity [GO:0004713]; ubiquitin protein ligase binding [GO:0031625]
d3gmdd__d4pzda1__1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]	fatty acid metabolic process [GO:0006631]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d3gmdh__d3tozh2__1	Metazoa		Chordata	Firmicutes	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]	cytosol [GO:0005829]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d3gmjb__d2ff4b3__1	Metazoa	Fungi	Arthropoda	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; heteromeric SMAD protein complex [GO:0071144]; nucleus [GO:0005634]; RNA polymerase II transcription repressor complex [GO:0090571]; transcription factor complex [GO:0005667]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region DNA binding [GO:0001012]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]; BMP signaling pathway [GO:0030509]; compound eye morphogenesis [GO:0001745]; dorsal closure [GO:0007391]; germ-line stem cell division [GO:0042078]; germ-line stem cell population maintenance [GO:0030718]; heart development [GO:0007507]; histoblast morphogenesis [GO:0007488]; imaginal disc morphogenesis [GO:0007560]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of salivary gland boundary specification [GO:0045705]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ovarian follicle cell development [GO:0030707]; positive regulation of neuromuscular junction development [GO:1904398]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R8 cell fate specification [GO:0045464]; regulation of cell differentiation [GO:0045595]; SMAD protein signal transduction [GO:0060395]; somatic stem cell population maintenance [GO:0035019]; transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification [GO:0060799]; trunk segmentation [GO:0035290]; ventral cord development [GO:0007419]; wing disc anterior/posterior pattern formation [GO:0048100]	chromatin [GO:0000785]; nucleus [GO:0005634]; double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; histone binding [GO:0042393]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; G1 DNA damage checkpoint [GO:0044783]; intra-S DNA damage checkpoint [GO:0031573]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of DNA replication [GO:0008156]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]	BMP signaling pathway [GO:0030509]; compound eye morphogenesis [GO:0001745]; dorsal closure [GO:0007391]; germ-line stem cell division [GO:0042078]; germ-line stem cell population maintenance [GO:0030718]; heart development [GO:0007507]; histoblast morphogenesis [GO:0007488]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc morphogenesis [GO:0007560]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of salivary gland boundary specification [GO:0045705]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ovarian follicle cell development [GO:0030707]; positive regulation of neuromuscular junction development [GO:1904398]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R8 cell fate specification [GO:0045464]; regulation of cell differentiation [GO:0045595]; SMAD protein signal transduction [GO:0060395]; somatic stem cell population maintenance [GO:0035019]; transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification [GO:0060799]; trunk segmentation [GO:0035290]; ventral cord development [GO:0007419]; wing disc anterior/posterior pattern formation [GO:0048100]	DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; G1 DNA damage checkpoint [GO:0044783]; intra-S DNA damage checkpoint [GO:0031573]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of DNA replication [GO:0008156]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; heteromeric SMAD protein complex [GO:0071144]; nucleus [GO:0005634]; RNA polymerase II transcription repressor complex [GO:0090571]; transcription factor complex [GO:0005667]	chromatin [GO:0000785]; nucleus [GO:0005634]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region DNA binding [GO:0001012]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]	double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; histone binding [GO:0042393]
d3gmjc__d1yjmb___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; heteromeric SMAD protein complex [GO:0071144]; nucleus [GO:0005634]; RNA polymerase II transcription repressor complex [GO:0090571]; transcription factor complex [GO:0005667]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region DNA binding [GO:0001012]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]; BMP signaling pathway [GO:0030509]; compound eye morphogenesis [GO:0001745]; dorsal closure [GO:0007391]; germ-line stem cell division [GO:0042078]; germ-line stem cell population maintenance [GO:0030718]; heart development [GO:0007507]; histoblast morphogenesis [GO:0007488]; imaginal disc morphogenesis [GO:0007560]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of salivary gland boundary specification [GO:0045705]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ovarian follicle cell development [GO:0030707]; positive regulation of neuromuscular junction development [GO:1904398]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R8 cell fate specification [GO:0045464]; regulation of cell differentiation [GO:0045595]; SMAD protein signal transduction [GO:0060395]; somatic stem cell population maintenance [GO:0035019]; transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification [GO:0060799]; trunk segmentation [GO:0035290]; ventral cord development [GO:0007419]; wing disc anterior/posterior pattern formation [GO:0048100]	mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; double-stranded DNA binding [GO:0003690]; nucleoside monophosphate kinase activity [GO:0050145]; polynucleotide 3'-phosphatase activity [GO:0046403]; dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide phosphorylation [GO:0046939]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]	BMP signaling pathway [GO:0030509]; compound eye morphogenesis [GO:0001745]; dorsal closure [GO:0007391]; germ-line stem cell division [GO:0042078]; germ-line stem cell population maintenance [GO:0030718]; heart development [GO:0007507]; histoblast morphogenesis [GO:0007488]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc morphogenesis [GO:0007560]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of salivary gland boundary specification [GO:0045705]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ovarian follicle cell development [GO:0030707]; positive regulation of neuromuscular junction development [GO:1904398]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R8 cell fate specification [GO:0045464]; regulation of cell differentiation [GO:0045595]; SMAD protein signal transduction [GO:0060395]; somatic stem cell population maintenance [GO:0035019]; transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification [GO:0060799]; trunk segmentation [GO:0035290]; ventral cord development [GO:0007419]; wing disc anterior/posterior pattern formation [GO:0048100]	dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide phosphorylation [GO:0046939]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; heteromeric SMAD protein complex [GO:0071144]; nucleus [GO:0005634]; RNA polymerase II transcription repressor complex [GO:0090571]; transcription factor complex [GO:0005667]	mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region DNA binding [GO:0001012]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity [GO:0046404]; double-stranded DNA binding [GO:0003690]; nucleoside monophosphate kinase activity [GO:0050145]; polynucleotide 3'-phosphatase activity [GO:0046403]
d3gmla1_d1jfmd___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	anchored component of external side of plasma membrane [GO:0031362]; anchored component of plasma membrane [GO:0046658]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; natural killer cell lectin-like receptor binding [GO:0046703]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to lipopolysaccharide [GO:0071222]; defense response to bacterium [GO:0042742]; positive regulation of immune response to tumor cell [GO:0002839]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of macrophage activation [GO:0043032]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; susceptibility to natural killer cell mediated cytotoxicity [GO:0042271]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cellular response to exogenous dsRNA [GO:0071360]; cellular response to lipopolysaccharide [GO:0071222]; defense response to bacterium [GO:0042742]; positive regulation of immune response to tumor cell [GO:0002839]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of macrophage activation [GO:0043032]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; susceptibility to natural killer cell mediated cytotoxicity [GO:0042271]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	anchored component of external side of plasma membrane [GO:0031362]; anchored component of plasma membrane [GO:0046658]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	natural killer cell lectin-like receptor binding [GO:0046703]
d3gmlb__d1deef1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	pathogenesis [GO:0009405]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	IgG binding [GO:0019864]
d3gmmb__d6b0gc2__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; plasma membrane [GO:0005886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	anchored component of membrane [GO:0031225]; cell surface [GO:0009986]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3gmob__d4mq7a2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3gmqb__d4k07e___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d3gmra2_d3r8bb___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d3gmxa__d1xxmd___1			Actinobacteria	Proteobacteria		beta-lactamase activity [GO:0008800]; beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]		beta-lactam antibiotic catabolic process [GO:0030655]; response to antibiotic [GO:0046677]				beta-lactamase activity [GO:0008800]
d3gmzb__d1p8pa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d3gn0b__d5wgmb1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]
d3gn4d__d4v0cd___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cell cortex [GO:0005938]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; microvillus [GO:0005902]; myosin complex [GO:0016459]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; RNA polymerase II, holoenzyme [GO:0016591]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]; actin filament-based movement [GO:0030048]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of secretion [GO:0051046]; sensory perception of sound [GO:0007605]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	actin filament-based movement [GO:0030048]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of secretion [GO:0051046]; sensory perception of sound [GO:0007605]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	actin filament [GO:0005884]; cell cortex [GO:0005938]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; microvillus [GO:0005902]; myosin complex [GO:0016459]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; RNA polymerase II, holoenzyme [GO:0016591]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d3gn4h__d1jf0a___1	Metazoa	Metazoa	Chordata	Cnidaria	actin filament [GO:0005884]; cell cortex [GO:0005938]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; microvillus [GO:0005902]; myosin complex [GO:0016459]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; RNA polymerase II, holoenzyme [GO:0016591]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]; actin filament-based movement [GO:0030048]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of secretion [GO:0051046]; sensory perception of sound [GO:0007605]	calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]	actin filament-based movement [GO:0030048]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of secretion [GO:0051046]; sensory perception of sound [GO:0007605]	bioluminescence [GO:0008218]	actin filament [GO:0005884]; cell cortex [GO:0005938]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; microvillus [GO:0005902]; myosin complex [GO:0016459]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; RNA polymerase II, holoenzyme [GO:0016591]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]		actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	calcium ion binding [GO:0005509]
d3gn4h__d2q91b___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; cell cortex [GO:0005938]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; microvillus [GO:0005902]; myosin complex [GO:0016459]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; RNA polymerase II, holoenzyme [GO:0016591]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]; actin filament-based movement [GO:0030048]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of secretion [GO:0051046]; sensory perception of sound [GO:0007605]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	actin filament-based movement [GO:0030048]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of secretion [GO:0051046]; sensory perception of sound [GO:0007605]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	actin filament [GO:0005884]; cell cortex [GO:0005938]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; microvillus [GO:0005902]; myosin complex [GO:0016459]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; RNA polymerase II, holoenzyme [GO:0016591]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d3gn8a__d5x8xe___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; thyroid hormone receptor coactivator activity [GO:0030375]; transcription coactivator activity [GO:0003713]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; circadian regulation of gene expression [GO:0032922]; locomotor rhythm [GO:0045475]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription, DNA-templated [GO:0006355]; response to progesterone [GO:0032570]	histone deacetylase complex [GO:0000118]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; glucocorticoid receptor binding [GO:0035259]; histone deacetylase binding [GO:0042826]; Notch binding [GO:0005112]; nuclear hormone receptor binding [GO:0035257]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]; estrous cycle [GO:0044849]; lactation [GO:0007595]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072365]; regulation of lipid metabolic process [GO:0019216]; response to estradiol [GO:0032355]; response to organonitrogen compound [GO:0010243]	bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; circadian regulation of gene expression [GO:0032922]; locomotor rhythm [GO:0045475]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription, DNA-templated [GO:0006355]; response to progesterone [GO:0032570]	estrous cycle [GO:0044849]; lactation [GO:0007595]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072365]; regulation of lipid metabolic process [GO:0019216]; response to estradiol [GO:0032355]; response to organonitrogen compound [GO:0010243]	cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	histone deacetylase complex [GO:0000118]; membrane [GO:0016020]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]	aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; protein dimerization activity [GO:0046983]; protein domain specific binding [GO:0019904]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; thyroid hormone receptor coactivator activity [GO:0030375]; transcription coactivator activity [GO:0003713]	chromatin binding [GO:0003682]; glucocorticoid receptor binding [GO:0035259]; histone deacetylase binding [GO:0042826]; Notch binding [GO:0005112]; nuclear hormone receptor binding [GO:0035257]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; sequence-specific DNA binding [GO:0043565]; transcription corepressor activity [GO:0003714]
d3gncd2_d1ws9b1__1			Proteobacteria	Deinococcus-Thermus	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA hydrolase activity [GO:0044466]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]					acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA hydrolase activity [GO:0044466]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d3gnxa__d1xlea___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d3goia2_d3wxkd1__1	Metazoa		Chordata		cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]		ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d3gosb1_d6amyb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]
d3gosc1_d3tk8b___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]
d3goua__d1ngka___1	Metazoa		Chordata	Actinobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d3goua__d1y4pa___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3gouc__d1gzxc___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3gowa__d1yg8q___1				Proteobacteria		cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]		ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3gowe__d5g1rg___1				Proteobacteria		cytoplasm [GO:0005737]; serine-type endopeptidase activity [GO:0004252]				cytoplasm [GO:0005737]		serine-type endopeptidase activity [GO:0004252]
d3gp2a__d1mxeb___1	Metazoa	Metazoa	Chordata	Arthropoda	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; sarcolemma [GO:0042383]; sarcoplasmic reticulum membrane [GO:0033017]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; sodium channel inhibitor activity [GO:0019871]; titin binding [GO:0031432]; cardiac muscle cell contraction [GO:0086003]; cellular response to calcium ion [GO:0071277]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of sodium ion transmembrane transport [GO:1902306]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1902514]; regulation of cardiac muscle cell action potential [GO:0098901]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cell growth [GO:0001558]; regulation of cellular localization [GO:0060341]; regulation of cellular response to heat [GO:1900034]; regulation of heart contraction [GO:0008016]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of histone deacetylase activity [GO:1901725]; regulation of membrane depolarization [GO:0003254]; regulation of relaxation of cardiac muscle [GO:1901897]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of the force of heart contraction [GO:0002026]; regulation of transcription by RNA polymerase II [GO:0006357]; relaxation of cardiac muscle [GO:0055119]	cell [GO:0005623]; cell cortex [GO:0005938]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; myosin V complex [GO:0031475]; myosin VI complex [GO:0031476]; nucleoplasm [GO:0005654]; rhabdomere [GO:0016028]; spindle [GO:0005819]; calcium ion binding [GO:0005509]; myosin heavy chain binding [GO:0032036]; myosin V binding [GO:0031489]; myosin VI head/neck binding [GO:0070855]; actin filament-based movement [GO:0030048]; adaptation of rhodopsin mediated signaling [GO:0016062]; calcium-mediated signaling [GO:0019722]; cellular response to ethanol [GO:0071361]; centriole replication [GO:0007099]; deactivation of rhodopsin mediated signaling [GO:0016059]; kinetochore organization [GO:0051383]; metarhodopsin inactivation [GO:0016060]; muscle cell cellular homeostasis [GO:0046716]; photoreceptor cell axon guidance [GO:0072499]; positive regulation of cation channel activity [GO:2001259]; protein phosphorylation [GO:0006468]; regulation of light-activated channel activity [GO:0016061]; rhabdomere development [GO:0042052]; rhodopsin mediated signaling pathway [GO:0016056]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]	cardiac muscle cell contraction [GO:0086003]; cellular response to calcium ion [GO:0071277]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of sodium ion transmembrane transport [GO:1902306]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1902514]; regulation of cardiac muscle cell action potential [GO:0098901]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling [GO:0010649]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cell growth [GO:0001558]; regulation of cellular localization [GO:0060341]; regulation of cellular response to heat [GO:1900034]; regulation of heart contraction [GO:0008016]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of histone deacetylase activity [GO:1901725]; regulation of membrane depolarization [GO:0003254]; regulation of relaxation of cardiac muscle [GO:1901897]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of the force of heart contraction [GO:0002026]; regulation of transcription by RNA polymerase II [GO:0006357]; relaxation of cardiac muscle [GO:0055119]	actin filament-based movement [GO:0030048]; adaptation of rhodopsin mediated signaling [GO:0016062]; calcium-mediated signaling [GO:0019722]; cellular response to ethanol [GO:0071361]; centriole replication [GO:0007099]; deactivation of rhodopsin mediated signaling [GO:0016059]; kinetochore organization [GO:0051383]; metarhodopsin inactivation [GO:0016060]; muscle cell cellular homeostasis [GO:0046716]; photoreceptor cell axon guidance [GO:0072499]; positive regulation of cation channel activity [GO:2001259]; protein phosphorylation [GO:0006468]; regulation of light-activated channel activity [GO:0016061]; rhabdomere development [GO:0042052]; rhodopsin mediated signaling pathway [GO:0016056]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]	calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; sarcolemma [GO:0042383]; sarcoplasmic reticulum membrane [GO:0033017]	cell [GO:0005623]; cell cortex [GO:0005938]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; myosin V complex [GO:0031475]; myosin VI complex [GO:0031476]; nucleoplasm [GO:0005654]; rhabdomere [GO:0016028]; spindle [GO:0005819]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; sodium channel inhibitor activity [GO:0019871]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]; myosin heavy chain binding [GO:0032036]; myosin V binding [GO:0031489]; myosin VI head/neck binding [GO:0070855]
d3gp3b__d3kkkb___1			Proteobacteria	Apicomplexa	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]		cytosol [GO:0005829]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]	phosphoglycerate mutase activity [GO:0004619]
d3gp3c__d2a6pa___1			Proteobacteria	Actinobacteria	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]				2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]	
d3gp5a__d1c80a___1		Metazoa	Proteobacteria	Chordata	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]; 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; animal organ regeneration [GO:0031100]; carbohydrate phosphorylation [GO:0046835]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; positive regulation of glucokinase activity [GO:0033133]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	animal organ regeneration [GO:0031100]; carbohydrate phosphorylation [GO:0046835]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]; positive regulation of glucokinase activity [GO:0033133]; response to cAMP [GO:0051591]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to starvation [GO:0042594]		6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex [GO:0043540]; cytosol [GO:0005829]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]	6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; fructose-6-phosphate binding [GO:0070095]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]
d3gp5a__d2h4xb___1		Metazoa	Proteobacteria	Chordata	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]
d3gp7a2_d5i4db2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d3gp7b2_d4o1nd2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; peptidase activity [GO:0008233]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	peptidase activity [GO:0008233]
d3gp9a1_d5yihc___1				Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3gp9b1_d1vyal___1		Viridiplantae		Streptophyta	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]
d3gp9b1_d3fc9a1__1					ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3gp9e1_d3q89g___1				Firmicutes	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3gp9e1_d3ztqf___1				Aquificae	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3gpjb__d4r18e___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gpjj__d3d29n___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gpjl__d4qvvq___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gpjp__d5cz6y___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gpjv__d4hnzg1__1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; HslUV protease complex [GO:0009376]; kinetoplast [GO:0020023]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nuclear lumen [GO:0031981]; proteasome core complex [GO:0005839]; ATP-dependent peptidase activity [GO:0004176]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; mitochondrial DNA inheritance [GO:0033955]; mitochondrial DNA replication [GO:0006264]; proteolysis involved in cellular protein catabolic process [GO:0051603]; rolling circle DNA replication [GO:0070581]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	mitochondrial DNA inheritance [GO:0033955]; mitochondrial DNA replication [GO:0006264]; proteolysis involved in cellular protein catabolic process [GO:0051603]; rolling circle DNA replication [GO:0070581]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; HslUV protease complex [GO:0009376]; kinetoplast [GO:0020023]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nuclear lumen [GO:0031981]; proteasome core complex [GO:0005839]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	ATP-dependent peptidase activity [GO:0004176]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gpjx__d5l67g___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gpna1_d4mjpa3__1	Fungi		Ascomycota	Proteobacteria	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3gpsb__d3i9aa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3gpth__d5jhrs___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gptu__d1jjwb___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]
d3gpw1__d1rypx___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gpwa__d4r17g___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gpwe__d2rf8a___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	choloylglycine hydrolase activity [GO:0045302]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	choloylglycine hydrolase activity [GO:0045302]
d3gpwh__d5l6cu___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gpwk__d3shjj___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gpwm__d3unfn___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gpwm__d4eu2z___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gpwp__d5l5sc___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gpwq__d4qwxe___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3gq0b__d4ykac___1			Proteobacteria	Proteobacteria	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]				
d3gq3a2_d1z5aa1__1			Firmicutes	Crenarchaeota	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]			class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]
d3gqba1_d5ik2d1__1			Deinococcus-Thermus	Firmicutes	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]		plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3gqba4_d1e79c1__1		Metazoa	Deinococcus-Thermus	Chordata	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3gqbb1_d2jdid2__1		Metazoa	Deinococcus-Thermus	Chordata	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3gqbb2_d1u9ic1__1			Deinococcus-Thermus	Cyanobacteria	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	circadian rhythm [GO:0007623]; entrainment of circadian clock [GO:0009649]; negative regulation of circadian rhythm [GO:0042754]; regulation of phosphorelay signal transduction system [GO:0070297]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]
d3gqbc4_d5ik2i3__1			Deinococcus-Thermus	Firmicutes	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]		plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3gqbd1_d3a5cd1__1			Deinococcus-Thermus	Deinococcus-Thermus	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]			ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3gqbd2_d3kqkb1__1			Deinococcus-Thermus		ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3gqbd3_d3j9tf3__1		Fungi	Deinococcus-Thermus	Ascomycota	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]		cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]
d3gqfa__d1uxmk___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d3gqgc__d1bijd___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3gqpa__d1hcoa___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3gqpb__d3s1ia___1	Metazoa		Chordata	Verrucomicrobia	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3gqpc__d2c0kb___1	Metazoa	Metazoa	Chordata	Arthropoda	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3gqpd__d1ngkk___1	Metazoa		Chordata	Actinobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d3gqrb__d5x2uc___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3gr6g__d1u3vb2__1		Metazoa	Firmicutes	Chordata	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity [GO:0047117]; NADP binding [GO:0050661]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity [GO:0047117]; NADP binding [GO:0050661]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d3gr6g__d4hwkd___1		Metazoa	Firmicutes	Chordata	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity [GO:0047117]; NADP binding [GO:0050661]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; aldo-keto reductase (NADP) activity [GO:0004033]; NADP binding [GO:0050661]; sepiapterin reductase activity [GO:0004757]; cofactor metabolic process [GO:0051186]; nitric oxide biosynthetic process [GO:0006809]; oxidation-reduction process [GO:0055114]; regulation of nitric-oxide synthase activity [GO:0050999]; tetrahydrobiopterin biosynthetic process [GO:0006729]	fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	cofactor metabolic process [GO:0051186]; nitric oxide biosynthetic process [GO:0006809]; oxidation-reduction process [GO:0055114]; regulation of nitric-oxide synthase activity [GO:0050999]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity [GO:0047117]; NADP binding [GO:0050661]	aldo-keto reductase (NADP) activity [GO:0004033]; NADP binding [GO:0050661]; sepiapterin reductase activity [GO:0004757]
d3gr6j1_d3rj9a___1		Metazoa	Firmicutes	Arthropoda	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity [GO:0047117]; NADP binding [GO:0050661]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]; alcohol metabolic process [GO:0006066]	fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	alcohol metabolic process [GO:0006066]			enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity [GO:0047117]; NADP binding [GO:0050661]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]
d3gr7a__d4utla___1			Firmicutes	Proteobacteria	FMN binding [GO:0010181]; NADP binding [GO:0050661]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]; response to toxic substance [GO:0009636]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	response to toxic substance [GO:0009636]				FMN binding [GO:0010181]; NADP binding [GO:0050661]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3gr8a__d4a3ua___1			Firmicutes	Proteobacteria	FMN binding [GO:0010181]; NADP binding [GO:0050661]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]; response to toxic substance [GO:0009636]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	response to toxic substance [GO:0009636]				FMN binding [GO:0010181]; NADP binding [GO:0050661]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3grbb__d1f41a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3grta3_d1aoga3__1	Metazoa		Chordata		cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]; cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; trypanothione-disulfide reductase activity [GO:0015042]
d3grwa1_d4fp8o1__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d3grwa2_d3o11l1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3grwl2_d4j4pb3__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3gsaa__d5t4la___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d3gsdc__d4yb6c2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	response to metal ion [GO:0010038]	histidine biosynthetic process [GO:0000105]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	copper ion binding [GO:0005507]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d3gsla1_d3stjf2__1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]
d3gslb1_d1x45a1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; amyloid-beta binding [GO:0001540]; axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; in utero embryonic development [GO:0001701]; intracellular protein transport [GO:0006886]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	axo-dendritic transport [GO:0008088]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid secretion [GO:0014051]; glutamate secretion [GO:0014047]; intracellular protein transport [GO:0006886]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; neurotransmitter secretion [GO:0007269]; protein-containing complex assembly [GO:0065003]; regulation of gene expression [GO:0010468]; regulation of synaptic vesicle exocytosis [GO:2000300]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic active zone membrane [GO:0048787]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]	amyloid-beta binding [GO:0001540]
d3gslb2_d4joha___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]; AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	AMPA glutamate receptor clustering [GO:0097113]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; dendritic spine morphogenesis [GO:0060997]; dendritic spine organization [GO:0097061]; establishment of protein localization [GO:0045184]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic transmission [GO:0050806]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	AMPA glutamate receptor complex [GO:0032281]; anchored component of postsynaptic density membrane [GO:0099031]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; excitatory synapse [GO:0060076]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuron spine [GO:0044309]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	acetylcholine receptor binding [GO:0033130]; beta-1 adrenergic receptor binding [GO:0031697]; beta-2 adrenergic receptor binding [GO:0031698]; D1 dopamine receptor binding [GO:0031748]; frizzled binding [GO:0005109]; glutamate receptor binding [GO:0035254]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor binding [GO:0035255]; kinesin binding [GO:0019894]; neuroligin family protein binding [GO:0097109]; P2Y1 nucleotide receptor binding [GO:0031812]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; structural constituent of postsynaptic density [GO:0098919]	ion channel binding [GO:0044325]
d3gsna1_d2f74a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3gsnb1_d1orqa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3gsnb1_d4byhb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3gspa__d1hyfa___1	Fungi	Fungi	Ascomycota	Ascomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d3gspa__d1jbta___1	Fungi	Fungi	Ascomycota	Ascomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	extracellular region [GO:0005576]; endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]; negative regulation of translation [GO:0017148]		negative regulation of translation [GO:0017148]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	extracellular region [GO:0005576]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; RNA binding [GO:0003723]
d3gsqa2_d1zs8h___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3gsqb1_d1dzbb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3gssb1_d2on7d2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	
d3gssb2_d3o3ta1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]
d3gstb2_d1j08e1__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	cell [GO:0005623]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d3gsub1_d1mela___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3gsva1_d2ianf2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3gsva2_d1jnha1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	plasma membrane [GO:0005886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3gswb1_d3b5hd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]
d3gswb1_d5m76b2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3gsxa2_d3upab___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]
d3gt6a__d4eldb___1			Proteobacteria	Euryarchaeota		cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; protein stabilization [GO:0050821]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]		identical protein binding [GO:0042802]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]
d3gt6b__d1rl1a___1		Metazoa	Proteobacteria	Chordata		cytosol [GO:0005829]; kinetochore [GO:0000776]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; mitotic cell cycle [GO:0000278]; positive regulation by host of symbiont catalytic activity [GO:0043947]; protein stabilization [GO:0050821]; regulation of protein stability [GO:0031647]		mitotic cell cycle [GO:0000278]; positive regulation by host of symbiont catalytic activity [GO:0043947]; protein stabilization [GO:0050821]; regulation of protein stability [GO:0031647]		cytosol [GO:0005829]; kinetochore [GO:0000776]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]		
d3gtta__d4oh2c___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; aging [GO:0007568]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to nutrient levels [GO:0031667]; response to organic substance [GO:0010033]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; aging [GO:0007568]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to nutrient levels [GO:0031667]; response to organic substance [GO:0010033]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d3gtub2_d1agsb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione transferase activity [GO:0004364]
d3gtuc1_d1jlve1__1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	glutathione transferase activity [GO:0004364]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]		enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione transferase activity [GO:0004364]
d3gtvb__d2yqwb___1	Metazoa		Chordata		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]		chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	
d3gtve__d1f1gd___1	Metazoa	Fungi	Chordata	Ascomycota	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]
d3gtvj__d1uxle___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d3guaf1_d1uw6r___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3gufa__d2h53i1__1		Viridiplantae	Proteobacteria	Streptophyta		cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]		cytoplasm [GO:0005737]		protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]
d3gura2_d4pnfh2__1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytoplasm [GO:0005737]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	glutathione transferase activity [GO:0004364]
d3gurb2_d5ecif2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d3gurc2_d1aqwb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3gurd2_d4kaeb2__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; isomerase activity [GO:0016853]; aromatic amino acid family metabolic process [GO:0009072]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	aromatic amino acid family metabolic process [GO:0009072]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	cytoplasm [GO:0005737]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]	isomerase activity [GO:0016853]
d3gvdc1_d5jxxb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	cysteine biosynthetic process from serine [GO:0006535]	lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	serine O-acetyltransferase activity [GO:0009001]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]
d3gvdd__d4knxa2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cysteine biosynthetic process from serine [GO:0006535]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	serine O-acetyltransferase activity [GO:0009001]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d3gvdf__d1khra___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cysteine biosynthetic process from serine [GO:0006535]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]		serine O-acetyltransferase activity [GO:0009001]	transferase activity, transferring acyl groups [GO:0016746]
d3gvdk__d1kk5d___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	cysteine biosynthetic process from serine [GO:0006535]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]		serine O-acetyltransferase activity [GO:0009001]	transferase activity, transferring acyl groups [GO:0016746]
d3gvga__d1mo0b___1		Metazoa	Actinobacteria	Nematoda (roundworms)	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cell [GO:0005623]; cytosol [GO:0005829]; myofibril [GO:0030016]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; cell redox homeostasis [GO:0045454]; determination of adult lifespan [GO:0008340]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cell redox homeostasis [GO:0045454]; determination of adult lifespan [GO:0008340]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; myofibril [GO:0030016]	triose-phosphate isomerase activity [GO:0004807]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]
d3gvha1_d4ijue___1		Metazoa	Proteobacteria	Chordata	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	L-malate dehydrogenase activity [GO:0030060]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d3gvha1_d5mlnb___1		Fungi	Proteobacteria	Ascomycota	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	oxidoreductase activity [GO:0016491]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]				L-malate dehydrogenase activity [GO:0030060]	oxidoreductase activity [GO:0016491]
d3gvha2_d1gv1c2__1			Proteobacteria	Chlorobi	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]			L-malate dehydrogenase activity [GO:0030060]	L-malate dehydrogenase activity [GO:0030060]
d3gvha2_d2hjrk2__1			Proteobacteria	Apicomplexa	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]			L-malate dehydrogenase activity [GO:0030060]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3gvhd2_d4ojna2__1		Metazoa	Proteobacteria	Chordata	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-malate dehydrogenase activity [GO:0030060]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d3gvib2_d1sevb2__1		Viridiplantae	Proteobacteria	Streptophyta	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		glyoxysome [GO:0009514]	L-malate dehydrogenase activity [GO:0030060]	L-malate dehydrogenase activity [GO:0030060]
d3gvie2_d3wsvd2__1			Proteobacteria	Firmicutes	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d3gvif2_d2aa3c2__1			Proteobacteria	Apicomplexa	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]			L-malate dehydrogenase activity [GO:0030060]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d3gvka1_d1v0ed1__1					virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	virus tail, fiber [GO:0098024]	virus tail, fiber [GO:0098024]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]
d3gvkc1_d1v0eb1__1					virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	virus tail, fiber [GO:0098024]	virus tail, fiber [GO:0098024]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]
d3gvkc1_d3k3aa___1				Negarnaviricota	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	virus tail, fiber [GO:0098024]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3gvla1_d1nmbn___1				Negarnaviricota	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	virus tail, fiber [GO:0098024]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3gvma1_d3favd___1			Firmicutes	Actinobacteria		cell wall [GO:0005618]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; host cell surface binding [GO:0046812]; protein homodimerization activity [GO:0042803]; modulation by symbiont of host signal transduction pathway [GO:0052027]; negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein secretion by the type VII secretion system [GO:0044315]		modulation by symbiont of host signal transduction pathway [GO:0052027]; negative regulation by symbiont of host cell-mediated immune response [GO:0052083]; pathogenesis [GO:0009405]; protein secretion by the type VII secretion system [GO:0044315]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell plasma membrane [GO:0020002]; host cell surface [GO:0044228]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		host cell surface binding [GO:0046812]; protein homodimerization activity [GO:0042803]
d3gvoa__d1ug3a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of chromosome segregation [GO:0051983]; regulation of mRNA stability [GO:0043488]; regulation of translation [GO:0006417]; stress granule assembly [GO:0034063]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; membrane [GO:0016020]; nucleus [GO:0005634]; polysome [GO:0005844]; ATP binding [GO:0005524]; eukaryotic initiation factor 4E binding [GO:0008190]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; translation factor activity, RNA binding [GO:0008135]; translation initiation factor activity [GO:0003743]; translation initiation factor binding [GO:0031369]; behavioral fear response [GO:0001662]; cap-dependent translational initiation [GO:0002191]; cellular macromolecule biosynthetic process [GO:0034645]; cellular response to nutrient levels [GO:0031669]; developmental process [GO:0032502]; energy homeostasis [GO:0097009]; negative regulation of autophagy [GO:0010507]; negative regulation of neuron death [GO:1901215]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth [GO:0030307]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of eukaryotic translation initiation factor 4F complex assembly [GO:1905537]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of mRNA cap binding [GO:1905612]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of cellular response to stress [GO:0080135]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; regulation of polysome binding [GO:1905696]; regulation of presynapse assembly [GO:1905606]; regulation of translational initiation [GO:0006446]; translation [GO:0006412]; translational initiation [GO:0006413]; viral process [GO:0016032]	positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of chromosome segregation [GO:0051983]; regulation of mRNA stability [GO:0043488]; regulation of translation [GO:0006417]; stress granule assembly [GO:0034063]	behavioral fear response [GO:0001662]; cap-dependent translational initiation [GO:0002191]; cellular macromolecule biosynthetic process [GO:0034645]; cellular response to nutrient levels [GO:0031669]; developmental process [GO:0032502]; energy homeostasis [GO:0097009]; negative regulation of autophagy [GO:0010507]; negative regulation of neuron death [GO:1901215]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth [GO:0030307]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of eukaryotic translation initiation factor 4F complex assembly [GO:1905537]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of mRNA cap binding [GO:1905612]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of cellular response to stress [GO:0080135]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; regulation of polysome binding [GO:1905696]; regulation of presynapse assembly [GO:1905606]; regulation of translational initiation [GO:0006446]; translation [GO:0006412]; translational initiation [GO:0006413]; viral process [GO:0016032]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; eukaryotic translation initiation factor 4F complex [GO:0016281]; membrane [GO:0016020]; nucleus [GO:0005634]; polysome [GO:0005844]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; eukaryotic initiation factor 4E binding [GO:0008190]; identical protein binding [GO:0042802]; molecular adaptor activity [GO:0060090]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; translation factor activity, RNA binding [GO:0008135]; translation initiation factor activity [GO:0003743]; translation initiation factor binding [GO:0031369]
d3gvwa__d1r3wa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uroporphyrinogen decarboxylase activity [GO:0004853]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uroporphyrinogen decarboxylase activity [GO:0004853]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	uroporphyrinogen decarboxylase activity [GO:0004853]	uroporphyrinogen decarboxylase activity [GO:0004853]
d3gvya__d3a9qj___1		Viridiplantae	Proteobacteria	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3gvyb__d5d8xd___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3gw0a__d4qqua2__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uroporphyrinogen decarboxylase activity [GO:0004853]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cell surface [GO:0009986]; fungal biofilm matrix [GO:0062040]; fungal-type cell wall [GO:0009277]; hyphal cell wall [GO:0030446]; nucleus [GO:0005634]; 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity [GO:0003871]; zinc ion binding [GO:0008270]; cellular response to heat [GO:0034605]; induction by symbiont of host defense response [GO:0044416]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cellular response to heat [GO:0034605]; induction by symbiont of host defense response [GO:0044416]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cell surface [GO:0009986]; fungal biofilm matrix [GO:0062040]; fungal-type cell wall [GO:0009277]; hyphal cell wall [GO:0030446]; nucleus [GO:0005634]	uroporphyrinogen decarboxylase activity [GO:0004853]	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity [GO:0003871]; zinc ion binding [GO:0008270]
d3gw1a__d1rqua2__1			Proteobacteria	Proteobacteria	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; large ribosomal subunit [GO:0015934]; protein homodimerization activity [GO:0042803]; ribosome binding [GO:0043022]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	translation [GO:0006412]		cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; large ribosomal subunit [GO:0015934]		protein homodimerization activity [GO:0042803]; ribosome binding [GO:0043022]; structural constituent of ribosome [GO:0003735]
d3gw1b__d4yjmc___1			Proteobacteria	Proteobacteria	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]				
d3gw5a__d1hvhb___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3gw8b__d1nd6c___1		Metazoa	Proteobacteria	Chordata	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]; adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]		azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]	5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]
d3gw9b__d1io7a___1				Crenarchaeota	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]
d3gw9c__d2gqxb___1				Proteobacteria	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	(+)-camphor catabolic process [GO:0019383]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3gw9c__d5ofqb___1				Firmicutes	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3gwaa1_d1m3zd2__1			Proteobacteria	Proteobacteria	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3gwaa1_d2gfwa2__1			Proteobacteria	Proteobacteria	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]		cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d3gwab1_d4jara1__1			Proteobacteria	Actinobacteria	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	polyketide synthase complex [GO:0034081]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		polyketide synthase complex [GO:0034081]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d3gwab1_d4z8db2__1			Proteobacteria	Proteobacteria	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d3gwab2_d4dfed2__1			Proteobacteria	Proteobacteria	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d3gweb2_d1i89b2__1		Viridiplantae	Proteobacteria	Streptophyta	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]	chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]			3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	naringenin-chalcone synthase activity [GO:0016210]
d3gweb2_d2gp6a1__1			Proteobacteria	Actinobacteria	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to hypoxia [GO:0001666]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to hypoxia [GO:0001666]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d3gwkc1_d4j42b___1			Firmicutes	Firmicutes								
d3gwke1_d4j11a1__1			Firmicutes	Firmicutes								
d3gwla1_d1oqca___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; pathogenesis [GO:0009405]	cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]; cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573]; response to lipopolysaccharide [GO:0032496]	pathogenesis [GO:0009405]	cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573]; response to lipopolysaccharide [GO:0032496]	host cell cytoplasm [GO:0030430]	cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	flavin-linked sulfhydryl oxidase activity [GO:0016971]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]
d3gwlb1_d1jrab___1		Fungi		Ascomycota	host cell cytoplasm [GO:0030430]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; pathogenesis [GO:0009405]	fungal-type vacuole [GO:0000324]; fungal-type vacuole membrane [GO:0000329]; integral component of endoplasmic reticulum membrane [GO:0030176]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]; oxidation-reduction process [GO:0055114]	pathogenesis [GO:0009405]	oxidation-reduction process [GO:0055114]	host cell cytoplasm [GO:0030430]	fungal-type vacuole [GO:0000324]; fungal-type vacuole membrane [GO:0000329]; integral component of endoplasmic reticulum membrane [GO:0030176]; mitochondrion [GO:0005739]	flavin-linked sulfhydryl oxidase activity [GO:0016971]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]
d3gwma__d1f7ta1__1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]	holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]
d3gx0a1_d2gdrb1__1			Proteobacteria	Proteobacteria	disulfide oxidoreductase activity [GO:0015036]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	glutathione transferase activity [GO:0004364]	response to oxidative stress [GO:0006979]				disulfide oxidoreductase activity [GO:0015036]; peroxidase activity [GO:0004601]	glutathione transferase activity [GO:0004364]
d3gxae__d3il1b___1		Metazoa	Proteobacteria	Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3gxaf__d2i4ca___1			Proteobacteria	Cyanobacteria		plasma membrane [GO:0005886]; ion transport [GO:0006811]		ion transport [GO:0006811]		plasma membrane [GO:0005886]		
d3gxdc2_d3vija___1	Metazoa	Metazoa	Chordata	Arthropoda	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3gxfa2_d3gxia2__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d3gxfa2_d4tx6a___1	Metazoa	Fungi	Chordata	Ascomycota	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3gxfb2_d1jz0h5__1	Metazoa		Chordata		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	
d3gxfc2_d2d22b1__1	Metazoa		Chordata	Actinobacteria	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	polysaccharide catabolic process [GO:0000272]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	endo-1,4-beta-xylanase activity [GO:0031176]
d3gxib2_d5m9xb1__1	Metazoa		Chordata	Actinobacteria	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	sucrose phosphorylase activity [GO:0009018]; cellular carbohydrate metabolic process [GO:0044262]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	cellular carbohydrate metabolic process [GO:0044262]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	sucrose phosphorylase activity [GO:0009018]
d3gxic2_d2je8b5__1	Metazoa		Chordata	Bacteroidetes	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	beta-mannosidase activity [GO:0004567]
d3gxkd__d4rw2a___1	Metazoa	Metazoa	Chordata	Chordata	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3gxmb2_d1i75b4__1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	extracellular region [GO:0005576]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3gxmc2_d1goqa___1	Metazoa	Fungi	Chordata	Ascomycota	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	xylan catabolic process [GO:0045493]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	endo-1,4-beta-xylanase activity [GO:0031176]
d3gxmd2_d1xsid4__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d3gxnb2_d3edja3__1	Metazoa		Chordata	Bacteroidetes	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d3gxpa1_d1v02a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3gxpb1_d3scsb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d3gxpb1_d5cpqa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	amyloplast [GO:0009501]; chloroplast [GO:0009507]; 4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; glucose metabolic process [GO:0006006]; maltose catabolic process [GO:0000025]; starch catabolic process [GO:0005983]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	glucose metabolic process [GO:0006006]; maltose catabolic process [GO:0000025]; starch catabolic process [GO:0005983]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	amyloplast [GO:0009501]; chloroplast [GO:0009507]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]
d3gxta1_d1b3wa___1	Metazoa	Fungi	Chordata	Ascomycota	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	xylan catabolic process [GO:0045493]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	endo-1,4-beta-xylanase activity [GO:0031176]
d3gxta2_d3h53b2__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d3gxtb1_d2oxna1__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cytoplasm [GO:0005737]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; peptidoglycan-based cell wall biogenesis [GO:0009273]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan-based cell wall biogenesis [GO:0009273]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	cytoplasm [GO:0005737]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]
d3gxtb2_d2pweb2__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3gxtb2_d3vgea3__1	Metazoa		Chordata	Crenarchaeota	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	trehalose biosynthetic process [GO:0005992]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	cytoplasm [GO:0005737]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]
d3gy0a__d5thkc___1			Proteobacteria	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]
d3gyja2_d2igod2__1		Fungi	Actinobacteria	Basidiomycota	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	cholesterol metabolic process [GO:0008203]		extracellular region [GO:0005576]		cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]
d3gymb__d3sued___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3gysb__d5aqdf___1	Metazoa		Chordata	Cyanobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3gysd__d3ozua1__1	Metazoa		Chordata	Proteobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3gyse__d5mbaa___1	Metazoa	Metazoa	Chordata	Mollusca	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3gysh__d5mjma___1	Metazoa		Chordata	Cyanobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3gz0a__d3mnka___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3gzga__d4p0ia___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; molybdate ion binding [GO:0030973]; tungstate binding [GO:1901359]; molybdate ion transport [GO:0015689]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	molybdate ion transport [GO:0015689]	nitrogen compound transport [GO:0071705]		membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]; molybdate ion binding [GO:0030973]; tungstate binding [GO:1901359]	ligand-gated ion channel activity [GO:0015276]
d3gzgc__d3csba2__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; molybdate ion binding [GO:0030973]; tungstate binding [GO:1901359]; molybdate ion transport [GO:0015689]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	molybdate ion transport [GO:0015689]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; molybdate ion binding [GO:0030973]; tungstate binding [GO:1901359]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3gzmb__d4dxeh1__1			Apicomplexa	Firmicutes	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acyl carrier activity [GO:0000036]	fatty acid biosynthetic process [GO:0006633]			cytoplasm [GO:0005737]		acyl carrier activity [GO:0000036]
d3gznj1_d3mhsd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]; cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein modification process [GO:0006464]; endomitotic cell cycle [GO:0007113]; negative regulation of transcription, DNA-templated [GO:0045892]; post-translational protein modification [GO:0043687]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116]; proteolysis [GO:0006508]; regulation of cell cycle [GO:0051726]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NEDD8 activating enzyme activity [GO:0019781]; NEDD8 transferase activity [GO:0019788]; nuclear receptor binding [GO:0016922]; protein heterodimerization activity [GO:0046982]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d3gzxa1_d1z03c1__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d3gzxa2_d1z03a2__1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d3gzya1_d1kb9e1__1		Fungi	Proteobacteria	Ascomycota	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	aromatic compound catabolic process [GO:0019439]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	biphenyl 2,3-dioxygenase activity [GO:0018687]	
d3gzyb__d2xsoj___1			Proteobacteria	Proteobacteria	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			biphenyl 2,3-dioxygenase activity [GO:0018687]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d3h03b__d4q30f___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3h03g__d3ppqa___1	Metazoa		Chordata	Firmicutes	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; amino acid transport [GO:0006865]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	amino acid transport [GO:0006865]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	transmembrane transporter activity [GO:0022857]
d3h06l__d4bdra___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d3h06l__d4oerb___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; heme binding [GO:0020037]; nickel cation binding [GO:0016151]; nickel cation transport [GO:0015675]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	nickel cation transport [GO:0015675]; transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	heme binding [GO:0020037]; nickel cation binding [GO:0016151]
d3h06p__d3ijxh___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3h0ca2_d4hrya___1	Metazoa	Viridiplantae	Chordata	Streptophyta	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytosol [GO:0005829]; nucleus [GO:0005634]; hydrolase activity [GO:0016787]; de-etiolation [GO:0009704]; photomorphogenesis [GO:0009640]; response to karrikin [GO:0080167]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	de-etiolation [GO:0009704]; photomorphogenesis [GO:0009640]; response to karrikin [GO:0080167]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; nucleus [GO:0005634]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	hydrolase activity [GO:0016787]
d3h0qc1_d2zl2n___1	Fungi		Ascomycota	Proteobacteria	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d3h0ua1_d1hzdd___1		Metazoa	Actinobacteria	Chordata	catalytic activity [GO:0003824]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]		branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]	enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]
d3h10a__d3h8pa___1	Metazoa		Chordata		axon hillock [GO:0043203]; centriole [GO:0005814]; centrosome [GO:0005813]; chromosome passenger complex [GO:0032133]; cilium [GO:0005929]; condensed nuclear chromosome, centromeric region [GO:0000780]; cytosol [GO:0005829]; germinal vesicle [GO:0042585]; meiotic spindle [GO:0072687]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle pole [GO:0097431]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle midzone [GO:0051233]; spindle pole centrosome [GO:0031616]; ATP binding [GO:0005524]; histone serine kinase activity [GO:0035174]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; ubiquitin protein ligase binding [GO:0031625]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; anterior/posterior axis specification [GO:0009948]; cell division [GO:0051301]; centrosome localization [GO:0051642]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; G2/M transition of mitotic cell cycle [GO:0000086]; liver regeneration [GO:0097421]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neuron projection extension [GO:1990138]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autophosphorylation [GO:0046777]; protein localization to centrosome [GO:0071539]; protein phosphorylation [GO:0006468]; regulation of centrosome cycle [GO:0046605]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to wounding [GO:0009611]; spindle assembly involved in female meiosis I [GO:0007057]; spindle organization [GO:0007051]; ubiquitin-dependent protein catabolic process [GO:0006511]		anaphase-promoting complex-dependent catabolic process [GO:0031145]; anterior/posterior axis specification [GO:0009948]; cell division [GO:0051301]; centrosome localization [GO:0051642]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; G2/M transition of mitotic cell cycle [GO:0000086]; liver regeneration [GO:0097421]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neuron projection extension [GO:1990138]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autophosphorylation [GO:0046777]; protein localization to centrosome [GO:0071539]; protein phosphorylation [GO:0006468]; regulation of centrosome cycle [GO:0046605]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to wounding [GO:0009611]; spindle assembly involved in female meiosis I [GO:0007057]; spindle organization [GO:0007051]; ubiquitin-dependent protein catabolic process [GO:0006511]		axon hillock [GO:0043203]; centriole [GO:0005814]; centrosome [GO:0005813]; chromosome passenger complex [GO:0032133]; cilium [GO:0005929]; condensed nuclear chromosome, centromeric region [GO:0000780]; cytosol [GO:0005829]; germinal vesicle [GO:0042585]; meiotic spindle [GO:0072687]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle pole [GO:0097431]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle midzone [GO:0051233]; spindle pole centrosome [GO:0031616]		ATP binding [GO:0005524]; histone serine kinase activity [GO:0035174]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625]	
d3h12b2_d4zcwa2__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cellular amino acid catabolic process [GO:0009063]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3h1aa__d2aj8c2__1		Metazoa		Chordata	hydrolase activity [GO:0016787]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	hydrolase activity [GO:0016787]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3h1ea__d1p6qa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]		metal ion binding [GO:0046872]	
d3h1fa__d1fqwa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	metal ion binding [GO:0046872]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d3h1ja1_d3l71b2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d3h1jb1_d1ntka1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3h1jb1_d3l72o2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d3h1jb2_d3h1jn2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d3h1jd1_d2fyud1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3h1je2_d3foua___1	Metazoa		Chordata	Deinococcus-Thermus	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]
d3h1jo1_d2ibzb1__1	Metazoa	Fungi	Chordata	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	
d3h1vx2_d4dcha2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]
d3h23a__d3tyzb___1			Firmicutes	Proteobacteria	dihydropteroate synthase activity [GO:0004156]; metal ion binding [GO:0046872]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydropteroate synthase activity [GO:0004156]; metal ion binding [GO:0046872]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydropteroate synthase activity [GO:0004156]; metal ion binding [GO:0046872]	dihydropteroate synthase activity [GO:0004156]; metal ion binding [GO:0046872]
d3h2ve1_d3hi9c___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; membrane raft [GO:0045121]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; terminal web [GO:1990357]; zonula adherens [GO:0005915]; actin binding [GO:0003779]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]; adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; muscle contraction [GO:0006936]; negative regulation of cell migration [GO:0030336]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; protein localization to cell surface [GO:0034394]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; muscle contraction [GO:0006936]; negative regulation of cell migration [GO:0030336]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; protein localization to cell surface [GO:0034394]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; membrane raft [GO:0045121]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; terminal web [GO:1990357]; zonula adherens [GO:0005915]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]	actin binding [GO:0003779]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]	AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d3h2vg1_d2lmia1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; membrane raft [GO:0045121]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; terminal web [GO:1990357]; zonula adherens [GO:0005915]; actin binding [GO:0003779]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]; adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; muscle contraction [GO:0006936]; negative regulation of cell migration [GO:0030336]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; protein localization to cell surface [GO:0034394]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; ribonucleoprotein granule [GO:0035770]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; anterior/posterior pattern specification [GO:0009952]; morphogenesis of embryonic epithelium [GO:0016331]; mRNA polyadenylation [GO:0006378]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; tRNA processing [GO:0008033]	adherens junction assembly [GO:0034333]; apical junction assembly [GO:0043297]; axon extension [GO:0048675]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; epithelial cell-cell adhesion [GO:0090136]; lamellipodium assembly [GO:0030032]; morphogenesis of an epithelium [GO:0002009]; muscle contraction [GO:0006936]; negative regulation of cell migration [GO:0030336]; neutrophil degranulation [GO:0043312]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; protein localization to cell surface [GO:0034394]	anterior/posterior pattern specification [GO:0009952]; morphogenesis of embryonic epithelium [GO:0016331]; mRNA polyadenylation [GO:0006378]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; tRNA processing [GO:0008033]	adherens junction [GO:0005912]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular vesicle [GO:1903561]; fascia adherens [GO:0005916]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inner dense plaque of desmosome [GO:0090637]; membrane raft [GO:0045121]; outer dense plaque of desmosome [GO:0090636]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; terminal web [GO:1990357]; zonula adherens [GO:0005915]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; ribonucleoprotein granule [GO:0035770]	actin binding [GO:0003779]; alpha-catenin binding [GO:0045294]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; dystroglycan binding [GO:0002162]; structural molecule activity [GO:0005198]; ubiquitin protein ligase binding [GO:0031625]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d3h33a__d1ofwb___1			Proteobacteria	Proteobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfur utilization [GO:0006791]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfur utilization [GO:0006791]			periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3h3bb1_d3b2um1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d3h3bc1_d4ogyn2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]	
d3h3bd1_d1mhhc2__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]	
d3h3fb2_d4ajjb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d3h3fc1_d5uzha___1	Metazoa		Chordata	Heterolobosea	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	GDP-mannose 4,6-dehydratase activity [GO:0008446]; GDP-mannose metabolic process [GO:0019673]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	GDP-mannose metabolic process [GO:0019673]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	GDP-mannose 4,6-dehydratase activity [GO:0008446]
d3h3fd2_d2hjra2__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3h3fe1_d1xhla___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3h3fh1_d4ei2c1__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	potassium ion transport [GO:0006813]	cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	L-lactate dehydrogenase activity [GO:0004459]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3h3ja1_d1qydc___1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	lariciresinol reductase activity [GO:0010284]; pinoresinol reductase activity [GO:0010283]; (+)-lariciresinol biosynthetic process [GO:1902132]; (+)-pinoresinol catabolic process [GO:1902125]; (+)-secoisolariciresinol biosynthetic process [GO:1902135]; (-)-lariciresinol biosynthetic process [GO:1902129]; (-)-lariciresinol catabolic process [GO:1902128]; (-)-pinoresinol catabolic process [GO:1902123]; lignan biosynthetic process [GO:0009807]	glycolytic process [GO:0006096]	(-)-lariciresinol biosynthetic process [GO:1902129]; (-)-lariciresinol catabolic process [GO:1902128]; (-)-pinoresinol catabolic process [GO:1902123]; (+)-lariciresinol biosynthetic process [GO:1902132]; (+)-pinoresinol catabolic process [GO:1902125]; (+)-secoisolariciresinol biosynthetic process [GO:1902135]; lignan biosynthetic process [GO:0009807]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	lariciresinol reductase activity [GO:0010284]; pinoresinol reductase activity [GO:0010283]
d3h3ja1_d4urfa___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3h3no1_d1ngha1__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]		autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d3h3no2_d2qwra2__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]		autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d3h3nx1_d1gleg2__1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]		cytosol [GO:0005829]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d3h3nx1_d4rcha2__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]		cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]
d3h3ob1_d3r6ma1__1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	tRNA threonylcarbamoyladenosine modification [GO:0002949]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	
d3h42l1_d4d9ln2__1	Metazoa		Chordata		cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor recycling [GO:0001920]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]		apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of receptor recycling [GO:0001920]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]		cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]		apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]	
d3h42l2_d5esvd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor recycling [GO:0001920]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of receptor recycling [GO:0001920]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3h45c1_d5fpea1__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	blood microparticle [GO:0072562]; CatSper complex [GO:0036128]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; meiotic spindle [GO:0072687]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptonemal complex [GO:0000795]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; glycolipid binding [GO:0051861]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; tau protein binding [GO:0048156]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein phosphorylation [GO:0001934]; protein refolding [GO:0042026]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex disassembly [GO:0070194]; vesicle-mediated transport [GO:0016192]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein phosphorylation [GO:0001934]; protein refolding [GO:0042026]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex disassembly [GO:0070194]; vesicle-mediated transport [GO:0016192]		blood microparticle [GO:0072562]; CatSper complex [GO:0036128]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; meiotic spindle [GO:0072687]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptonemal complex [GO:0000795]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; glycolipid binding [GO:0051861]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; tau protein binding [GO:0048156]; unfolded protein binding [GO:0051082]
d3h45d1_d5aqfa2__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3h45d2_d3h45c1__1			Firmicutes	Firmicutes	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]			ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d3h45x2_d1dgkn2__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]		cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d3h46o2_d5aqmc1__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3h4aa__d1tmmb___1				Proteobacteria		2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]		folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]				2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]
d3h4ej2_d3g1gb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]; aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral procapsid maturation [GO:0046797]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral procapsid maturation [GO:0046797]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d3h4el2_d4ipyc___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3h4fa2_d3t71b3__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3h4fb2_d4m4rh___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	adherens junction [GO:0005912]; anchored component of external side of plasma membrane [GO:0031362]; basement membrane [GO:0005604]; caveola [GO:0005901]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]; chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; neurotrophin TRKA receptor binding [GO:0005168]; neurotrophin TRKB receptor binding [GO:0005169]; neurotrophin TRKC receptor binding [GO:0005170]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; axon guidance [GO:0007411]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to forskolin [GO:1904322]; collateral sprouting [GO:0048668]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; nervous system development [GO:0007399]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell morphogenesis [GO:0022604]; regulation of cell-cell adhesion [GO:0022407]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of microtubule cytoskeleton organization [GO:0070507]; retinal ganglion cell axon guidance [GO:0031290]; synaptic membrane adhesion [GO:0099560]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	axon guidance [GO:0007411]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to forskolin [GO:1904322]; collateral sprouting [GO:0048668]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; nervous system development [GO:0007399]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell morphogenesis [GO:0022604]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of microtubule cytoskeleton organization [GO:0070507]; retinal ganglion cell axon guidance [GO:0031290]; synaptic membrane adhesion [GO:0099560]	periplasmic space [GO:0042597]	adherens junction [GO:0005912]; anchored component of external side of plasma membrane [GO:0031362]; basement membrane [GO:0005604]; caveola [GO:0005901]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; neurotrophin TRKA receptor binding [GO:0005168]; neurotrophin TRKB receptor binding [GO:0005169]; neurotrophin TRKC receptor binding [GO:0005170]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]
d3h4fc1_d5tb7b1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3h4fc2_d3t6wc1__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3h4ha1_d1oe2a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3h4hb1_d1tkwa___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3h4hc1_d3x2qb2__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d3h4pa__d4inuf___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3h4pd__d4qvqc___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3h4pf__d4z1lq___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3h4pn__d4no1j___1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3h53a1_d4gpnb___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	6-phospho-beta-glucosidase activity [GO:0008706]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]	6-phospho-beta-glucosidase activity [GO:0008706]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]
d3h53b1_d3t2qc3__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	beta-galactosidase complex [GO:0009341]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3h54b1_d2qpua2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	extracellular space [GO:0005615]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d3h55a1_d1jz5c5__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	beta-galactosidase complex [GO:0009341]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3h55b1_d1ea9d3__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	cyclomaltodextrinase activity [GO:0047798]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]	cyclomaltodextrinase activity [GO:0047798]
d3h55b2_d1v3la3__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3h56a1_d3fswb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3h5bb__d5p6da___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3h5da1_d2wnqa1__1				Proteobacteria		cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]		carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]		cytosol [GO:0005829]		identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d3h5ia__d5dkfb___1			Firmicutes	Proteobacteria	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d3h5va__d1lbga2__1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	negative regulation of transcription, DNA-templated [GO:0045892]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cytosol [GO:0005829]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]
d3h60a__d3kbpb2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	extracellular region [GO:0005576]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]
d3h60a__d5b8ia___1	Metazoa	Fungi	Chordata	Ascomycota	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	phosphoprotein phosphatase activity [GO:0004721]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	phosphoprotein phosphatase activity [GO:0004721]
d3h61d__d3dw8f___1	Metazoa	Metazoa	Chordata	Chordata	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]
d3h63a__d4dhlb2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	extracellular region [GO:0005576]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]
d3h64a__d1s3na___1	Metazoa		Chordata	Euryarchaeota	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3h64d__d1hpua2__1	Metazoa		Chordata	Proteobacteria	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	nucleotide catabolic process [GO:0009166]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	outer membrane-bounded periplasmic space [GO:0030288]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]
d3h65a1_d2hjrc1__1			Euryarchaeota	Apicomplexa	N5,N10-methenyltetrahydromethanopterin hydrogenase activity [GO:0047068]; methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	methanogenesis, from carbon dioxide [GO:0019386]; one-carbon metabolic process [GO:0006730]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]			N5,N10-methenyltetrahydromethanopterin hydrogenase activity [GO:0047068]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3h66b__d1qhwa___1	Metazoa	Metazoa	Chordata	Chordata	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; bone resorption [GO:0045453]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell adhesion [GO:0007162]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of cell migration [GO:0030335]; response to cholesterol [GO:0070723]; response to L-ascorbic acid [GO:0033591]; response to organic cyclic compound [GO:0014070]; response to zinc ion [GO:0010043]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	bone resorption [GO:0045453]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell adhesion [GO:0007162]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of cell migration [GO:0030335]; response to cholesterol [GO:0070723]; response to L-ascorbic acid [GO:0033591]; response to organic cyclic compound [GO:0014070]; response to zinc ion [GO:0010043]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]
d3h66b__d4xpna1__1	Metazoa	Metazoa	Chordata	Chordata	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]
d3h69a__d1xzwa2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	extracellular region [GO:0005576]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]
d3h6da1_d2bt1a1__1			Actinobacteria		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUTP metabolic process [GO:0046080]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]
d3h6ha__d3c6qb___1	Metazoa		Chordata	Thermotogae	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]		axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	
d3h6ha__d4yr7b___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]		axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	periplasmic space [GO:0042597]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	
d3h6tc__d5dtba___1	Metazoa	Metazoa	Chordata	Arthropoda	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell [GO:0005623]; cell junction [GO:0030054]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic active zone [GO:0048786]; glutamate receptor activity [GO:0008066]; glutamate-gated calcium ion channel activity [GO:0022849]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; calcium ion import across plasma membrane [GO:0098703]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of neuromuscular synaptic transmission [GO:1900075]; regulation of synaptic activity [GO:0060025]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	calcium ion import across plasma membrane [GO:0098703]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of neuromuscular synaptic transmission [GO:1900075]; regulation of synaptic activity [GO:0060025]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell [GO:0005623]; cell junction [GO:0030054]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic active zone [GO:0048786]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	glutamate-gated calcium ion channel activity [GO:0022849]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3h6va1_d2f34b___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d3h6wb1_d3g41a___1	Metazoa		Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d3h76b1_d2vbac1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]; fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d3h76b2_d1d9ba1__1			Proteobacteria		cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]; fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]		fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]		cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]	
d3h78b2_d2vb7c2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]; fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; secondary metabolite biosynthetic process [GO:0044550]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; transferase activity, transferring acyl groups [GO:0016746]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d3h7pa__d2d5gc1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	beta-catenin destruction complex [GO:0030877]; cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein homooligomerization [GO:0051260]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein homooligomerization [GO:0051260]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	beta-catenin destruction complex [GO:0030877]; cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]
d3h7pa__d2lgda___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein serine/threonine phosphatase activity [GO:0004722]; protein dephosphorylation [GO:0006470]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	protein dephosphorylation [GO:0006470]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	protein serine/threonine phosphatase activity [GO:0004722]
d3h7sa__d2iy1b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d3h7wb__d1jnud___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; regulation of heart rate [GO:0002027]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; surfactant homeostasis [GO:0043129]; transcription by RNA polymerase II [GO:0006366]; visual perception [GO:0007601]	detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]		DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]
d3h83a1_d1dqpb___1			Firmicutes		cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	transferase activity, transferring glycosyl groups [GO:0016757]; nucleoside metabolic process [GO:0009116]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]		guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	transferase activity, transferring glycosyl groups [GO:0016757]
d3h86c__d1efrd3__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]		ATP synthesis coupled proton transport [GO:0015986]	cytoplasm [GO:0005737]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3h86g__d1huqa___1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]	anchored component of synaptic vesicle membrane [GO:0098993]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; lipid droplet [GO:0005811]; melanosome [GO:0042470]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; plasma membrane to endosome transport [GO:0048227]; Rab protein signal transduction [GO:0032482]; regulation of endocytosis [GO:0030100]		endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; plasma membrane to endosome transport [GO:0048227]; Rab protein signal transduction [GO:0032482]; regulation of endocytosis [GO:0030100]	cytoplasm [GO:0005737]	anchored component of synaptic vesicle membrane [GO:0098993]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; lipid droplet [GO:0005811]; melanosome [GO:0042470]; plasma membrane [GO:0005886]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d3h8ka__d3r42a___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; dendrite [GO:0030425]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; BAT3 complex binding [GO:1904288]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-specific protease binding [GO:1990381]; ubiquitin-ubiquitin ligase activity [GO:0034450]; aging [GO:0007568]; endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; learning or memory [GO:0007611]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of protein binding [GO:0032092]; protein autoubiquitination [GO:0051865]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT-0 complex [GO:0033565]; protein-containing complex [GO:0032991]; metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; ubiquitin binding [GO:0043130]; ATP export [GO:1904669]; late endosome to vacuole transport [GO:0045324]; multivesicular body sorting pathway [GO:0071985]; positive regulation of protein maturation [GO:1903319]; protein retention in Golgi apparatus [GO:0045053]; protein secretion [GO:0009306]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]	aging [GO:0007568]; endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; learning or memory [GO:0007611]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of protein binding [GO:0032092]; protein autoubiquitination [GO:0051865]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	ATP export [GO:1904669]; late endosome to vacuole transport [GO:0045324]; multivesicular body sorting pathway [GO:0071985]; positive regulation of protein maturation [GO:1903319]; protein retention in Golgi apparatus [GO:0045053]; protein secretion [GO:0009306]; protein targeting to vacuole [GO:0006623]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]	cytosol [GO:0005829]; dendrite [GO:0030425]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	cell [GO:0005623]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT-0 complex [GO:0033565]; protein-containing complex [GO:0032991]	BAT3 complex binding [GO:1904288]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-specific protease binding [GO:1990381]; ubiquitin-ubiquitin ligase activity [GO:0034450]	metal ion binding [GO:0046872]; phosphatidylinositol-3-phosphate binding [GO:0032266]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; ubiquitin binding [GO:0043130]
d3h8ma__d1b0xa___1	Metazoa	Metazoa	Chordata	Chordata	dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; brain development [GO:0007420]; branching morphogenesis of a nerve [GO:0048755]; ephrin receptor signaling pathway [GO:0048013]; negative chemotaxis [GO:0050919]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of synapse assembly [GO:0051964]; nephric duct morphogenesis [GO:0072178]; phosphorylation [GO:0016310]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell-cell adhesion [GO:0022407]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of postsynapse organization [GO:0099175]; regulation of protein autophosphorylation [GO:0031952]; retinal ganglion cell axon guidance [GO:0031290]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	adherens junction [GO:0005912]; axon [GO:0030424]; axon terminus [GO:0043679]; axonal growth cone [GO:0044295]; cell body [GO:0044297]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; mitochondrial outer membrane [GO:0005741]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]; ATP binding [GO:0005524]; DH domain binding [GO:0097161]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; PH domain binding [GO:0042731]; protein kinase activity [GO:0004672]; protein tyrosine kinase binding [GO:1990782]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to amyloid-beta [GO:1904646]; cochlea development [GO:0090102]; corticospinal tract morphogenesis [GO:0021957]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; negative regulation of axon regeneration [GO:0048681]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron projection development [GO:0010977]; negative regulation of proteolysis involved in cellular protein catabolic process [GO:1903051]; nephric duct morphogenesis [GO:0072178]; neuron projection fasciculation [GO:0106030]; neuron projection guidance [GO:0097485]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of astrocyte differentiation [GO:0048710]; regulation of axonogenesis [GO:0050770]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of modification of synaptic structure [GO:1905244]; synapse pruning [GO:0098883]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	apoptotic process [GO:0006915]; axon guidance [GO:0007411]; brain development [GO:0007420]; branching morphogenesis of a nerve [GO:0048755]; ephrin receptor signaling pathway [GO:0048013]; negative chemotaxis [GO:0050919]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of synapse assembly [GO:0051964]; nephric duct morphogenesis [GO:0072178]; phosphorylation [GO:0016310]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell-cell adhesion [GO:0022407]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of postsynapse organization [GO:0099175]; regulation of protein autophosphorylation [GO:0031952]; retinal ganglion cell axon guidance [GO:0031290]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to amyloid-beta [GO:1904646]; cochlea development [GO:0090102]; corticospinal tract morphogenesis [GO:0021957]; ephrin receptor signaling pathway [GO:0048013]; fasciculation of motor neuron axon [GO:0097156]; fasciculation of sensory neuron axon [GO:0097155]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; negative regulation of axon regeneration [GO:0048681]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of neuron projection development [GO:0010977]; negative regulation of proteolysis involved in cellular protein catabolic process [GO:1903051]; nephric duct morphogenesis [GO:0072178]; neuron projection fasciculation [GO:0106030]; neuron projection guidance [GO:0097485]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of astrocyte differentiation [GO:0048710]; regulation of axonogenesis [GO:0050770]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of GTPase activity [GO:0043087]; regulation of modification of synaptic structure [GO:1905244]; synapse pruning [GO:0098883]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]	adherens junction [GO:0005912]; axon [GO:0030424]; axonal growth cone [GO:0044295]; axon terminus [GO:0043679]; cell body [GO:0044297]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; filopodium [GO:0030175]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; mitochondrial outer membrane [GO:0005741]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]	ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; protein tyrosine kinase activity [GO:0004713]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	ATP binding [GO:0005524]; DH domain binding [GO:0097161]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; PH domain binding [GO:0042731]; protein kinase activity [GO:0004672]; protein tyrosine kinase binding [GO:1990782]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3h8ma__d2lmra1__1	Metazoa	Metazoa	Chordata	Chordata	dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; brain development [GO:0007420]; branching morphogenesis of a nerve [GO:0048755]; ephrin receptor signaling pathway [GO:0048013]; negative chemotaxis [GO:0050919]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of synapse assembly [GO:0051964]; nephric duct morphogenesis [GO:0072178]; phosphorylation [GO:0016310]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell-cell adhesion [GO:0022407]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of postsynapse organization [GO:0099175]; regulation of protein autophosphorylation [GO:0031952]; retinal ganglion cell axon guidance [GO:0031290]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; ephrin receptor binding [GO:0046875]; ephrin receptor signaling pathway [GO:0048013]; neuron remodeling [GO:0016322]; regulation of ephrin receptor signaling pathway [GO:1901187]; substrate-dependent cell migration [GO:0006929]	apoptotic process [GO:0006915]; axon guidance [GO:0007411]; brain development [GO:0007420]; branching morphogenesis of a nerve [GO:0048755]; ephrin receptor signaling pathway [GO:0048013]; negative chemotaxis [GO:0050919]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of synapse assembly [GO:0051964]; nephric duct morphogenesis [GO:0072178]; phosphorylation [GO:0016310]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell-cell adhesion [GO:0022407]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of postsynapse organization [GO:0099175]; regulation of protein autophosphorylation [GO:0031952]; retinal ganglion cell axon guidance [GO:0031290]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	ephrin receptor signaling pathway [GO:0048013]; neuron remodeling [GO:0016322]; regulation of ephrin receptor signaling pathway [GO:1901187]; substrate-dependent cell migration [GO:0006929]	dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; Schaffer collateral - CA1 synapse [GO:0098685]	cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]	ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; GPI-linked ephrin receptor activity [GO:0005004]; protein tyrosine kinase activity [GO:0004713]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	ephrin receptor binding [GO:0046875]
d3h8na1_d1h9va1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; MHC class Ib protein binding [GO:0023029]; innate immune response [GO:0045087]	Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]	innate immune response [GO:0045087]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	MHC class Ib protein binding [GO:0023029]	IgG binding [GO:0019864]
d3h8na2_d1kj2b___1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; MHC class Ib protein binding [GO:0023029]; innate immune response [GO:0045087]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	innate immune response [GO:0045087]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	MHC class Ib protein binding [GO:0023029]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3h8qa1_d4mh2k___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin-disulfide reductase activity [GO:0004791]; cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin-disulfide reductase activity [GO:0004791]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d3h8qb1_d5a5kn1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin-disulfide reductase activity [GO:0004791]; cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; protein disulfide oxidoreductase activity [GO:0015035]; thioredoxin-disulfide reductase activity [GO:0004791]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d3h8wa2_d5hmma2__1					5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; exonuclease activity [GO:0004527]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, Okazaki fragment processing [GO:0033567]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; exodeoxyribonuclease activity [GO:0004529]; metal ion binding [GO:0046872]; DNA replication, Okazaki fragment processing [GO:0033567]; viral DNA genome replication [GO:0039693]	DNA replication, Okazaki fragment processing [GO:0033567]	DNA replication, Okazaki fragment processing [GO:0033567]; viral DNA genome replication [GO:0039693]			5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; exonuclease activity [GO:0004527]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; exodeoxyribonuclease activity [GO:0004529]; metal ion binding [GO:0046872]
d3h8ya__d3sssd1__1			Proteobacteria	Cyanobacteria		identical protein binding [GO:0042802]						identical protein binding [GO:0042802]
d3h90b2_d3bypa1__1			Proteobacteria	Deinococcus-Thermus	cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cadmium ion transmembrane transporter activity [GO:0015086]; cation transmembrane transporter activity [GO:0008324]; ferrous iron transmembrane transporter activity [GO:0015093]; identical protein binding [GO:0042802]; zinc efflux active transmembrane transporter activity [GO:0015341]; cadmium ion transport [GO:0015691]; cellular cadmium ion homeostasis [GO:0006876]; cellular iron ion homeostasis [GO:0006879]; cellular zinc ion homeostasis [GO:0006882]; iron ion transport [GO:0006826]; zinc ion transport [GO:0006829]	integral component of membrane [GO:0016021]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	cadmium ion transport [GO:0015691]; cellular cadmium ion homeostasis [GO:0006876]; cellular iron ion homeostasis [GO:0006879]; cellular zinc ion homeostasis [GO:0006882]; iron ion transport [GO:0006826]; zinc ion transport [GO:0006829]		cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]	cadmium ion transmembrane transporter activity [GO:0015086]; cation transmembrane transporter activity [GO:0008324]; ferrous iron transmembrane transporter activity [GO:0015093]; identical protein binding [GO:0042802]; zinc efflux active transmembrane transporter activity [GO:0015341]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3h9da__d2emsa3__1		Metazoa		Chordata	autophagosome [GO:0005776]; cytoplasm [GO:0005737]; phagophore assembly site [GO:0000407]; autophagosome assembly [GO:0000045]; cellular response to nitrogen starvation [GO:0006995]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	autophagosome assembly [GO:0000045]; cellular response to nitrogen starvation [GO:0006995]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	autophagosome [GO:0005776]; cytoplasm [GO:0005737]; phagophore assembly site [GO:0000407]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]		actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d3h9hb1_d1a4kh2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3h9hb1_d5xqyg___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3h9he1_d2gsia1__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; membrane [GO:0016020]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3h9kc__d4foxd___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytosol [GO:0005829]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP catabolic process [GO:0046079]; response to antibiotic [GO:0046677]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP catabolic process [GO:0046079]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cytosol [GO:0005829]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	thymidylate synthase activity [GO:0004799]
d3h9na1_d2bvna1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ribosome [GO:0005840]; ribosome binding [GO:0043022]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; ribosome [GO:0005840]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	ribosome binding [GO:0043022]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3h9rb__d4j4nc___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein dimerization activity [GO:0046983]; chaperone-mediated protein folding [GO:0061077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	chaperone-mediated protein folding [GO:0061077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]	FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein dimerization activity [GO:0046983]
d3h9sb1_d1s5hb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3h9ya1_d4gt7d2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3h9ya2_d3naal1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3h9ya2_d4r4ba2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3h9yb1_d3qfjd1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3h9yb2_d1t5xa1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d3h9yb2_d1wcbh1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3h9ye2_d1rzgd2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3h9za2_d3c5zb2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d3h9zb2_d3ngbl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	structural molecule activity [GO:0005198]
d3h9zc1_d3f58l2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3h9zc1_d4kk9d1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3h9zd1_d4wwkb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ha0a1_d4kkbf2__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3ha0b1_d3g5xc1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3ha0b2_d4odvl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3ha0b2_d5f3hh1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]; cell development [GO:0048468]; cellular response to dexamethasone stimulus [GO:0071549]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of kinase activity [GO:0033673]; negative regulation of muscle hypertrophy [GO:0014741]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast proliferation [GO:2000818]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; negative regulation of skeletal muscle tissue growth [GO:0048632]; ovulation cycle process [GO:0022602]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; response to electrical stimulus [GO:0051602]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to gravity [GO:0009629]; response to heat [GO:0009408]; response to muscle activity [GO:0014850]; response to testosterone [GO:0033574]; skeletal muscle atrophy [GO:0014732]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell development [GO:0048468]; cellular response to dexamethasone stimulus [GO:0071549]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of kinase activity [GO:0033673]; negative regulation of muscle hypertrophy [GO:0014741]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast proliferation [GO:2000818]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; negative regulation of skeletal muscle tissue growth [GO:0048632]; ovulation cycle process [GO:0022602]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; response to electrical stimulus [GO:0051602]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to gravity [GO:0009629]; response to heat [GO:0009408]; response to muscle activity [GO:0014850]; response to testosterone [GO:0033574]; skeletal muscle atrophy [GO:0014732]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]
d3ha0c1_d1flty___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]
d3ha0c1_d3wiim2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3ha0c2_d4m1dl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d3ha0d2_d4kkbd1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3ha0e1_d4eurb2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3hala__d3fj8a1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; organ induction [GO:0001759]; positive regulation of cell division [GO:0051781]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; organ induction [GO:0001759]; positive regulation of cell division [GO:0051781]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3hala__d4xfsb___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; nucleus [GO:0005634]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; organ induction [GO:0001759]; positive regulation of cell division [GO:0051781]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; organ induction [GO:0001759]; positive regulation of cell division [GO:0051781]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d3hb2p1_d1kl6a___1			Proteobacteria	Firmicutes	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3hb3b2_d2xx1a2__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	nitrogen compound metabolic process [GO:0006807]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3hb3c__d1ap2c___1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3hb4x__d2hlpa1__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]; estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]	L-malate dehydrogenase activity [GO:0030060]
d3hb8a__d4foaa1__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytosol [GO:0005829]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP catabolic process [GO:0046079]; response to antibiotic [GO:0046677]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP catabolic process [GO:0046079]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cytosol [GO:0005829]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	thymidylate synthase activity [GO:0004799]
d3hb8b__d4foxa___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytosol [GO:0005829]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP catabolic process [GO:0046079]; response to antibiotic [GO:0046677]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP catabolic process [GO:0046079]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cytosol [GO:0005829]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	thymidylate synthase activity [GO:0004799]
d3hb8d__d1dnab___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cytosol [GO:0005829]	cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]
d3hbda__d2rsca1__1	Viridiplantae	Metazoa	Streptophyta	Arthropoda	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]			chitinase activity [GO:0004568]; chitin binding [GO:0008061]	lysozyme activity [GO:0003796]
d3hbex__d1ip3a___1	Viridiplantae	Metazoa	Streptophyta	Chordata	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3hbex__d1wvua___1	Viridiplantae		Streptophyta	Actinobacteria	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]		extracellular region [GO:0005576]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]
d3hbha__d4z3ma___1	Viridiplantae	Metazoa	Streptophyta	Chordata	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3hbpa1_d3hbqa1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]
d3hbpa2_d2dmca1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	actin cytoskeleton organization [GO:0030036]; cellular response to interferon-gamma [GO:0071346]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	actin cytoskeleton [GO:0015629]; brush border [GO:0005903]; cell [GO:0005623]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; Z disc [GO:0030018]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]	actin binding [GO:0003779]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d3hbpa2_d4iefd2__1	Metazoa		Chordata	Bacteroidetes	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; pathogenesis [GO:0009405]; proteolysis [GO:0006508]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	pathogenesis [GO:0009405]; proteolysis [GO:0006508]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d3hbqa2_d2omya1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3hbwb__d1pzzb___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; filopodium [GO:0030175]; growth cone [GO:0030426]; intercalated disc [GO:0014704]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; beta-tubulin binding [GO:0048487]; growth factor activity [GO:0008083]; ion channel binding [GO:0044325]; microtubule binding [GO:0008017]; protein kinase activator activity [GO:0030295]; sodium channel regulator activity [GO:0017080]; cell-cell signaling [GO:0007267]; cerebral cortex cell migration [GO:0021795]; establishment of neuroblast polarity [GO:0045200]; hippocampus development [GO:0021766]; learning [GO:0007612]; MAPK cascade [GO:0000165]; memory [GO:0007613]; microtubule polymerization [GO:0046785]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; protein localization to plasma membrane [GO:0072659]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; signal transduction [GO:0007165]; sodium ion transport [GO:0006814]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell-cell signaling [GO:0007267]; cerebral cortex cell migration [GO:0021795]; establishment of neuroblast polarity [GO:0045200]; hippocampus development [GO:0021766]; learning [GO:0007612]; MAPK cascade [GO:0000165]; memory [GO:0007613]; microtubule polymerization [GO:0046785]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; protein localization to plasma membrane [GO:0072659]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; signal transduction [GO:0007165]; sodium ion transport [GO:0006814]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; filopodium [GO:0030175]; growth cone [GO:0030426]; intercalated disc [GO:0014704]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	beta-tubulin binding [GO:0048487]; growth factor activity [GO:0008083]; ion channel binding [GO:0044325]; microtubule binding [GO:0008017]; protein kinase activator activity [GO:0030295]; sodium channel regulator activity [GO:0017080]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3hc0b1_d3ijsc2__1												
d3hc0b1_d5yaxa2__1						integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; caveolin-mediated endocytosis of virus by host cell [GO:0075513]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]		caveolin-mediated endocytosis of virus by host cell [GO:0075513]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]		integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		
d3hc0b2_d3qeud2__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d3hc0l1_d5xjfa2__1		Metazoa		Chordata		extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]		extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		
d3hc0l2_d1d9kh1__1		Metazoa		Chordata		T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]		T cell receptor complex [GO:0042101]		
d3hc2a2_d1i75b1__1				Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3hc3l1_d1b6ua1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; signaling receptor activity [GO:0038023]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		immune response [GO:0006955]; regulation of immune response [GO:0050776]		integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; signaling receptor activity [GO:0038023]
d3hc3l2_d5lbsm___1						extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3hc8a__d5c29a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3hcab1_d3kqob1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	phenylethanolamine N-methyltransferase activity [GO:0004603]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d3hcab1_d5x0za___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	phenylethanolamine N-methyltransferase activity [GO:0004603]	spermidine synthase activity [GO:0004766]
d3hccb1_d2cl5a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	phenylethanolamine N-methyltransferase activity [GO:0004603]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d3hcda__d1zgja2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity [GO:0102670]; isoflavone 4'-O-methyltransferase activity [GO:0030746]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		phenylethanolamine N-methyltransferase activity [GO:0004603]	2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity [GO:0102670]; isoflavone 4'-O-methyltransferase activity [GO:0030746]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]
d3hcfb1_d5egsb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; histone methyltransferase activity [GO:0042054]; histone methyltransferase activity (H2A-R3 specific) [GO:0070612]; histone methyltransferase activity (H3-R2 specific) [GO:0070611]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; histone-arginine N-methyltransferase activity [GO:0008469]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; base-excision repair [GO:0006284]; cellular senescence [GO:0090398]; histone H3-R2 methylation [GO:0034970]; histone methylation [GO:0016571]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; viral process [GO:0016032]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	base-excision repair [GO:0006284]; cellular senescence [GO:0090398]; histone H3-R2 methylation [GO:0034970]; histone methylation [GO:0016571]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	phenylethanolamine N-methyltransferase activity [GO:0004603]	chromatin binding [GO:0003682]; histone-arginine N-methyltransferase activity [GO:0008469]; histone binding [GO:0042393]; histone methyltransferase activity [GO:0042054]; histone methyltransferase activity (H2A-R3 specific) [GO:0070612]; histone methyltransferase activity (H3-R2 specific) [GO:0070611]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]
d3hcka__d1cj1e___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]
d3hcmb__d2l50b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; response to calcium ion [GO:0051592]	astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	response to calcium ion [GO:0051592]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]
d3hcnb__d2ac2a___1	Metazoa		Chordata	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	heme biosynthetic process [GO:0006783]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]
d3hcob__d1c9ea___1	Metazoa		Chordata	Firmicutes	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cytoplasm [GO:0005737]; ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]; heme biosynthetic process [GO:0006783]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	heme biosynthetic process [GO:0006783]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	ferrochelatase activity [GO:0004325]; metal ion binding [GO:0046872]
d3hcob__d2xwqb___1	Metazoa		Chordata	Euryarchaeota	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]; anaerobic cobalamin biosynthetic process [GO:0019251]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	anaerobic cobalamin biosynthetic process [GO:0019251]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	cobalt ion binding [GO:0050897]; sirohydrochlorin cobaltochelatase activity [GO:0016852]; tetrapyrrole binding [GO:0046906]
d3hcpa__d4f4db___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]; cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	cellular response to dexamethasone stimulus [GO:0071549]; generation of precursor metabolites and energy [GO:0006091]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX metabolic process [GO:0046501]; response to arsenic-containing substance [GO:0046685]; response to ethanol [GO:0045471]; response to insecticide [GO:0017085]; response to lead ion [GO:0010288]; response to light stimulus [GO:0009416]; response to methylmercury [GO:0051597]; response to platinum ion [GO:0070541]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferrochelatase activity [GO:0004325]; ferrous iron binding [GO:0008198]
d3hcud__d4nrga___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; UBC13-MMS2 complex [GO:0031372]; UBC13-UEV1A complex [GO:0035370]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; activation of MAPK activity [GO:0000187]; cellular protein modification process [GO:0006464]; DNA double-strand break processing [GO:0000729]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone ubiquitination [GO:0016574]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of DNA repair [GO:0045739]; positive regulation of histone modification [GO:0031058]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of DNA repair [GO:0006282]; regulation of histone ubiquitination [GO:0033182]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	activation of MAPK activity [GO:0000187]; cellular protein modification process [GO:0006464]; DNA double-strand break processing [GO:0000729]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone ubiquitination [GO:0016574]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of DNA repair [GO:0045739]; positive regulation of histone modification [GO:0031058]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of DNA repair [GO:0006282]; regulation of histone ubiquitination [GO:0033182]; T cell receptor signaling pathway [GO:0050852]	DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; UBC13-MMS2 complex [GO:0031372]; UBC13-UEV1A complex [GO:0035370]; ubiquitin ligase complex [GO:0000151]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]	ATP binding [GO:0005524]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	ubiquitin conjugating enzyme activity [GO:0061631]
d3hdhb1_d1f17a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; positive regulation of cold-induced thermogenesis [GO:0120162]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	fatty acid beta-oxidation [GO:0006635]; positive regulation of cold-induced thermogenesis [GO:0120162]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d3hdhb2_d2pwzg1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; positive regulation of cold-induced thermogenesis [GO:0120162]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	fatty acid beta-oxidation [GO:0006635]; positive regulation of cold-induced thermogenesis [GO:0120162]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]
d3hdhc2_d2amfc2__1	Metazoa		Chordata	Firmicutes	mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; positive regulation of cold-induced thermogenesis [GO:0120162]	cytoplasm [GO:0005737]; nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]; L-proline biosynthetic process [GO:0055129]	fatty acid beta-oxidation [GO:0006635]; positive regulation of cold-induced thermogenesis [GO:0120162]	L-proline biosynthetic process [GO:0055129]	mitochondrial matrix [GO:0005759]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]	nucleotide binding [GO:0000166]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d3hdpa__d3ojnb1__1			Firmicutes	Actinobacteria	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					lyase activity [GO:0016829]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3hdsb1_d5b0ca___1		Viridiplantae	Proteobacteria	Streptophyta	isomerase activity [GO:0016853]	cytoplasm [GO:0005737]; cyclase activity [GO:0009975]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; cannabinoid biosynthetic process [GO:1901696]; olivetolic acid biosynthetic process [GO:1901697]		cannabinoid biosynthetic process [GO:1901696]; olivetolic acid biosynthetic process [GO:1901697]		cytoplasm [GO:0005737]	isomerase activity [GO:0016853]	cyclase activity [GO:0009975]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]
d3hdza__d5dh5b1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3he6a2_d1kirb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3he6c1_d3bn9e1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3he6c1_d3owek___1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3he7d1_d2wubl1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	proteolysis [GO:0006508]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]		serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3he8a__d2betd___1			Firmicutes	Actinobacteria	ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]	ribose-5-phosphate isomerase activity [GO:0004751]	ribose-5-phosphate isomerase activity [GO:0004751]
d3heaf__d3t52e___1			Proteobacteria	Proteobacteria	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]					arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]
d3heea__d1usla___1			Firmicutes	Actinobacteria	ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]	ribose-5-phosphate isomerase activity [GO:0004751]	ribose-5-phosphate isomerase activity [GO:0004751]
d3heeb__d2vvrf___1			Firmicutes	Proteobacteria	ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]	allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]; D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]	D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]			ribose-5-phosphate isomerase activity [GO:0004751]	allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]
d3heia__d2y6la1__1	Metazoa		Chordata	Bacteroidetes	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	xylan catabolic process [GO:0045493]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]		ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3heia__d4qdra1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	axon [GO:0030424]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; integral component of postsynaptic membrane [GO:0099055]; membrane [GO:0016020]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; semaphorin receptor activity [GO:0017154]; signaling receptor activity [GO:0038023]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; angiogenesis [GO:0001525]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to leukemia inhibitory factor [GO:1990830]; dorsal root ganglion morphogenesis [GO:1904835]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; negative chemotaxis [GO:0050919]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of postsynapse organization [GO:0099175]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; trigeminal ganglion development [GO:0061551]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]; viral process [GO:0016032]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	angiogenesis [GO:0001525]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to leukemia inhibitory factor [GO:1990830]; dorsal root ganglion morphogenesis [GO:1904835]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; negative chemotaxis [GO:0050919]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of postsynapse organization [GO:0099175]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; trigeminal ganglion development [GO:0061551]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]; viral process [GO:0016032]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	axon [GO:0030424]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; integral component of postsynaptic membrane [GO:0099055]; membrane [GO:0016020]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; semaphorin receptor activity [GO:0017154]; signaling receptor activity [GO:0038023]; vascular endothelial growth factor-activated receptor activity [GO:0005021]
d3heic__d4al9g___1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	carbohydrate binding [GO:0030246]
d3heid1_d1as7c2__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	periplasmic space [GO:0042597]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3heif1_d1mg3o___1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]		cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	periplasmic space [GO:0042597]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3heig__d5juva4__1	Metazoa	Fungi	Chordata	Ascomycota	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	extracellular region [GO:0005576]; beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]; carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]
d3heih1_d1kgyf___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3heik__d2vxjx___1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	carbohydrate binding [GO:0030246]
d3heil1_d1l9sa1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	periplasmic space [GO:0042597]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3heim__d1gmma___1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	xylan catabolic process [GO:0045493]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]		ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]
d3heim__d3jqwb___1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]; collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]
d3hein1_d2bwda1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	periplasmic space [GO:0042597]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3heio__d2lrpa1__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	cellulose catabolic process [GO:0030245]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]		ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	cellulase activity [GO:0008810]
d3heio__d5ifpa5__1	Metazoa	Fungi	Chordata	Ascomycota	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	extracellular region [GO:0005576]; beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]; carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	carbohydrate metabolic process [GO:0005975]; lactose catabolic process [GO:0005990]; polysaccharide catabolic process [GO:0000272]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	beta-galactosidase activity [GO:0004565]; oligosaccharide binding [GO:0070492]
d3hepa__d1ycaa___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3hf3b__d2vdca2__1			Deinococcus-Thermus	Proteobacteria	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	4 iron, 4 sulfur cluster binding [GO:0051539]; glutamate synthase (NADPH) activity [GO:0004355]; metal ion binding [GO:0046872]; L-glutamate biosynthetic process [GO:0097054]		L-glutamate biosynthetic process [GO:0097054]			FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	4 iron, 4 sulfur cluster binding [GO:0051539]; glutamate synthase (NADPH) activity [GO:0004355]; metal ion binding [GO:0046872]
d3hf3d__d3vzzb___1			Deinococcus-Thermus	Firmicutes	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	magnesium ion binding [GO:0000287]; polyprenyltransferase activity [GO:0002094]; glycerophospholipid biosynthetic process [GO:0046474]		glycerophospholipid biosynthetic process [GO:0046474]			FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	magnesium ion binding [GO:0000287]; polyprenyltransferase activity [GO:0002094]
d3hf4b__d3aq8a___1	Metazoa		Chordata	Ciliophora	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin beta binding [GO:0031722]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; glutathione metabolic process [GO:0006749]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; protein heterooligomerization [GO:0051291]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; glutathione metabolic process [GO:0006749]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; protein heterooligomerization [GO:0051291]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin beta binding [GO:0031722]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3hf4e__d2hbsh___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin beta binding [GO:0031722]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; glutathione metabolic process [GO:0006749]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; protein heterooligomerization [GO:0051291]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; glutathione metabolic process [GO:0006749]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; protein heterooligomerization [GO:0051291]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin beta binding [GO:0031722]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3hf5d1_d3hfkc1__1			Proteobacteria	Proteobacteria	isomerase activity [GO:0016853]	isomerase activity [GO:0016853]					isomerase activity [GO:0016853]	isomerase activity [GO:0016853]
d3hf5d1_d3qgpa1__1			Proteobacteria	Firmicutes	isomerase activity [GO:0016853]	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; heme catabolic process [GO:0042167]; iron import into cell [GO:0033212]		heme catabolic process [GO:0042167]; iron import into cell [GO:0033212]		cell [GO:0005623]; cytoplasm [GO:0005737]	isomerase activity [GO:0016853]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]
d3hfac__d4qxjc___1		Fungi	Actinobacteria	Ascomycota	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3hfae__d5l60o___1		Fungi	Actinobacteria	Ascomycota	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3hfax__d5lf1i___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3hfja__d5o08c1__1				Actinobacteria		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]		coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d3hfjb__d1gn8b___1				Proteobacteria		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]		coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d3hfka1_d5ag0b___1		Fungi	Proteobacteria	Basidiomycota	isomerase activity [GO:0016853]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]				extracellular region [GO:0005576]	isomerase activity [GO:0016853]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3hfmh1_d5f3bf2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]; cell development [GO:0048468]; cellular response to dexamethasone stimulus [GO:0071549]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of kinase activity [GO:0033673]; negative regulation of muscle hypertrophy [GO:0014741]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast proliferation [GO:2000818]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; negative regulation of skeletal muscle tissue growth [GO:0048632]; ovulation cycle process [GO:0022602]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; response to electrical stimulus [GO:0051602]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to gravity [GO:0009629]; response to heat [GO:0009408]; response to muscle activity [GO:0014850]; response to testosterone [GO:0033574]; skeletal muscle atrophy [GO:0014732]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell development [GO:0048468]; cellular response to dexamethasone stimulus [GO:0071549]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of kinase activity [GO:0033673]; negative regulation of muscle hypertrophy [GO:0014741]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast proliferation [GO:2000818]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; negative regulation of skeletal muscle tissue growth [GO:0048632]; ovulation cycle process [GO:0022602]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; response to electrical stimulus [GO:0051602]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to gravity [GO:0009629]; response to heat [GO:0009408]; response to muscle activity [GO:0014850]; response to testosterone [GO:0033574]; skeletal muscle atrophy [GO:0014732]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]
d3hfmy__d1g07a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3hfza__d2rhqa1__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	phenylalanyl-tRNA aminoacylation [GO:0006432]	phenylalanyl-tRNA aminoacylation [GO:0006432]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]
d3hg0a1_d1h7zb___1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	virus tail, baseplate [GO:0098025]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]		
d3hg2a1_d2gk1j1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d3hg2a2_d2zwyb2__1	Metazoa		Chordata	Thermotogae	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	lysosome [GO:0005764]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-L-fucosidase activity [GO:0004560]
d3hg2b1_d1u33a2__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3hg3a1_d3dc0a1__1	Metazoa		Chordata	Firmicutes	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d3hg3a1_d3pzqa___1	Metazoa		Chordata	Thermotogae	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]
d3hg3a2_d4go9a2__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3hg3b1_d3eddb2__1	Metazoa		Chordata	Bacteroidetes	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d3hg3b2_d1ob0a1__1	Metazoa		Chordata	Firmicutes	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d3hg4a1_d4xuyb___1	Metazoa	Fungi	Chordata	Ascomycota	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	xylan catabolic process [GO:0045493]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	endo-1,4-beta-xylanase activity [GO:0031176]
d3hg4b1_d2f2he4__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d3hg5b1_d3pzva___1	Metazoa		Chordata	Firmicutes	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cellulose catabolic process [GO:0030245]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]
d3hgjb__d4orma___1			Deinococcus-Thermus	Apicomplexa	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; dihydroorotate dehydrogenase activity [GO:0004152]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; response to drug [GO:0042493]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; response to drug [GO:0042493]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase activity [GO:0004152]
d3hgna__d5f03b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3hgpa__d5c1ya1__1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3hgxa__d4oj7b___1			Proteobacteria		carbon-oxygen lyase activity [GO:0016835]; chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]; chorismate metabolic process [GO:0046417]; pyochelin biosynthetic process [GO:0042864]; salicylic acid biosynthetic process [GO:0009697]		chorismate metabolic process [GO:0046417]; pyochelin biosynthetic process [GO:0042864]; salicylic acid biosynthetic process [GO:0009697]				carbon-oxygen lyase activity [GO:0016835]; chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]	
d3hgxb__d2h9dd___1			Proteobacteria	Proteobacteria	carbon-oxygen lyase activity [GO:0016835]; chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]; chorismate metabolic process [GO:0046417]; pyochelin biosynthetic process [GO:0042864]; salicylic acid biosynthetic process [GO:0009697]	carbon-oxygen lyase activity [GO:0016835]; chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]; chorismate metabolic process [GO:0046417]; pyochelin biosynthetic process [GO:0042864]; salicylic acid biosynthetic process [GO:0009697]	chorismate metabolic process [GO:0046417]; pyochelin biosynthetic process [GO:0042864]; salicylic acid biosynthetic process [GO:0009697]	chorismate metabolic process [GO:0046417]; pyochelin biosynthetic process [GO:0042864]; salicylic acid biosynthetic process [GO:0009697]			carbon-oxygen lyase activity [GO:0016835]; chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]	carbon-oxygen lyase activity [GO:0016835]; chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]
d3hh3a__d1ioca1__1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3hh5a__d5kiga___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3hh6a__d1lmna___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]; lysozyme activity [GO:0003796]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; metabolic process [GO:0008152]	host cell cytoplasm [GO:0030430]	extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3hh8a__d4utpb1__1			Firmicutes	Firmicutes	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; zinc ion transport [GO:0006829]	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	cell adhesion [GO:0007155]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; zinc ion transport [GO:0006829]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	plasma membrane [GO:0005886]	plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3hhbb__d4f6da___1	Metazoa	Metazoa	Chordata	Nemertea (ribbon worms)	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3hhpc1_d1pwza___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]		L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	
d3hhpc2_d4tvoa2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	L-malate dehydrogenase activity [GO:0030060]
d3hhpd2_d1d3ab2__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]	L-malate dehydrogenase activity [GO:0030060]
d3hhqc__d5y5of___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3hhqh__d1snfc___1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3hhqm__d4apz1___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3hhqr__d1euwa1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3hhqt__d1eu5a1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3hhqv__d1slha___1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3hhqw__d1q5uz1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d3hhqx__d1q5ux1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dITP catabolic process [GO:0035863]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; pyrimidine deoxyribonucleoside triphosphate catabolic process [GO:0009213]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	dITP diphosphatase activity [GO:0035870]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d3hhua__d3omua1__1	Metazoa		Chordata		axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d3hhva__d2oa7b2__1		Metazoa	Crenarchaeota	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]
d3hi4c__d1t4ma___1			Proteobacteria	Firmicutes	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d3hi4e__d1a88c___1			Proteobacteria	Actinobacteria	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	chloride peroxidase activity [GO:0016691]					arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	chloride peroxidase activity [GO:0016691]
d3hi4f__d4dnqc___1		Viridiplantae	Proteobacteria	Streptophyta	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	hydrolase activity, acting on ester bonds [GO:0016788]; secondary shoot formation [GO:0010223]; strigolactone biosynthetic process [GO:1901601]		secondary shoot formation [GO:0010223]; strigolactone biosynthetic process [GO:1901601]			arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	hydrolase activity, acting on ester bonds [GO:0016788]
d3hi5l2_d2cgrl1__1		Metazoa		Chordata								
d3hi5l2_d5wtga2__1												
d3hi6a__d1yvra2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; misfolded RNA binding [GO:0034336]; cell projection organization [GO:0030030]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cell projection organization [GO:0030030]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	cytoplasm [GO:0005737]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	metal ion binding [GO:0046872]; misfolded RNA binding [GO:0034336]
d3hi6l1_d2yssa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3hi6l1_d5uy3l1__1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]		cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]		cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	
d3hi6y2_d1dzba2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3hi9a__d2mpua___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	RNA binding [GO:0003723]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]		AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3hi9b__d4ed5a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]	AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]	AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d3hi9d__d1cvjh1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]; gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	gene silencing by RNA [GO:0031047]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; regulation of mRNA stability [GO:0043488]; translational initiation [GO:0006413]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]	mRNA 3'-UTR binding [GO:0003730]; poly(A) binding [GO:0008143]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; translation activator activity [GO:0008494]
d3hi9d__d2mqpa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; ribonucleoprotein complex [GO:1990904]; ribonucleoprotein granule [GO:0035770]; mRNA 3'-UTR binding [GO:0003730]; mRNA CDS binding [GO:1990715]; pre-mRNA intronic binding [GO:0097157]; transcription regulatory region DNA binding [GO:0044212]; cellular response to amino acid starvation [GO:0034198]; circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to peptide [GO:1901652]	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]	cellular response to amino acid starvation [GO:0034198]; circadian rhythm [GO:0007623]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to peptide [GO:1901652]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; ribonucleoprotein complex [GO:1990904]; ribonucleoprotein granule [GO:0035770]	AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]	mRNA 3'-UTR binding [GO:0003730]; mRNA CDS binding [GO:1990715]; pre-mRNA intronic binding [GO:0097157]; transcription regulatory region DNA binding [GO:0044212]
d3hiha2_d5lhzc___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]; anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; centrosome duplication [GO:0051298]; determination of left/right symmetry [GO:0007368]; embryonic axis specification [GO:0000578]; floor plate development [GO:0033504]; forebrain development [GO:0030900]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; mitotic spindle organization [GO:0007052]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord development [GO:0030903]; protein localization to centrosome [GO:0071539]; regulation of centriole replication [GO:0046599]; smoothened signaling pathway [GO:0007224]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	centrosome duplication [GO:0051298]; determination of left/right symmetry [GO:0007368]; embryonic axis specification [GO:0000578]; floor plate development [GO:0033504]; forebrain development [GO:0030900]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; mitotic spindle organization [GO:0007052]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord development [GO:0030903]; protein localization to centrosome [GO:0071539]; regulation of centriole replication [GO:0046599]; smoothened signaling pathway [GO:0007224]	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]	centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]	identical protein binding [GO:0042802]
d3hina__d2a7ke___1			Proteobacteria	Proteobacteria	3-hydroxybutyryl-CoA dehydratase activity [GO:0003859]	transferase activity [GO:0016740]; antibiotic biosynthetic process [GO:0017000]		antibiotic biosynthetic process [GO:0017000]			3-hydroxybutyryl-CoA dehydratase activity [GO:0003859]	transferase activity [GO:0016740]
d3hisb__d4zlba___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3hita__d5gm7a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3hiwa__d4zfwa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3hiwb__d4zgra___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3hj3a1_d1rb3a___1				Proteobacteria		cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d3hj3a2_d2aazb___1		Fungi		Basidiomycota		cytosol [GO:0005829]; mitochondrion [GO:0005739]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]		dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]		cytosol [GO:0005829]; mitochondrion [GO:0005739]		thymidylate synthase activity [GO:0004799]
d3hj3d1_d4kjla___1				Proteobacteria		cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d3hjba1_d5lu6c___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]
d3hjbb1_d2cxob___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	aldehyde catabolic process [GO:0046185]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; glycolytic process through glucose-6-phosphate [GO:0061620]; in utero embryonic development [GO:0001701]; learning or memory [GO:0007611]; mesoderm formation [GO:0001707]; methylglyoxal biosynthetic process [GO:0019242]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to morphine [GO:0043278]; response to muscle stretch [GO:0035994]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	cytosol [GO:0005829]	ciliary membrane [GO:0060170]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	glucose-6-phosphate isomerase activity [GO:0004347]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d3hjea1_d2d22a1__1			Crenarchaeota	Actinobacteria	(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity [GO:0047470]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]			(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity [GO:0047470]	endo-1,4-beta-xylanase activity [GO:0031176]
d3hjea2_d3olia2__1		Metazoa	Crenarchaeota	Chordata	(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity [GO:0047470]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity [GO:0047470]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3hjha1_d2eyqa3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	cytosol [GO:0005829]; ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription-coupled nucleotide-excision repair, DNA damage recognition [GO:0000716]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]	ATP binding [GO:0005524]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA translocase activity [GO:0015616]; RNA polymerase core enzyme binding [GO:0043175]
d3hjma2_d3fhsb4__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	
d3hjmb1_d1tu8d2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d3hjmc1_d1gsda2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3hjmc1_d4llre___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d3hjmc2_d1c72a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d3hjmd1_d4aj8b___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	protein disulfide oxidoreductase activity [GO:0015035]
d3hjoa2_d2c3qd2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]
d3hjob2_d4hz2a2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	transferase activity [GO:0016740]
d3hk1a__d5khpa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]
d3hk7f__d1ra0a2__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	cytosol [GO:0005829]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; isoguanine deaminase activity [GO:0035888]; zinc ion binding [GO:0008270]; cytosine catabolic process [GO:0006209]		cytosine catabolic process [GO:0006209]		cytosol [GO:0005829]	metal ion binding [GO:0046872]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; isoguanine deaminase activity [GO:0035888]; zinc ion binding [GO:0008270]
d3hk7j__d1a4mb___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; in utero embryonic development [GO:0001701]; inosine biosynthetic process [GO:0046103]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]		adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]		cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]
d3hk7k__d1r9za2__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	cytosol [GO:0005829]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; isoguanine deaminase activity [GO:0035888]; zinc ion binding [GO:0008270]; cytosine catabolic process [GO:0006209]		cytosine catabolic process [GO:0006209]		cytosol [GO:0005829]	metal ion binding [GO:0046872]	5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; isoguanine deaminase activity [GO:0035888]; zinc ion binding [GO:0008270]
d3hk9a__d1hzya___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	plasma membrane [GO:0005886]; aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]; catabolic process [GO:0009056]		catabolic process [GO:0009056]		plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]
d3hk9b__d4lefh___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; zinc ion binding [GO:0008270]; catabolic process [GO:0009056]		catabolic process [GO:0009056]			metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; zinc ion binding [GO:0008270]
d3hk9d__d1pscb___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	plasma membrane [GO:0005886]; aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]; catabolic process [GO:0009056]		catabolic process [GO:0009056]		plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]
d3hk9f__d2bgng1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3hk9j__d4ofcb___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminocarboxymuconate-semialdehyde decarboxylase activity [GO:0001760]; hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]; negative regulation of quinolinate biosynthetic process [GO:1904985]; picolinic acid biosynthetic process [GO:1905004]; regulation of 'de novo' NAD biosynthetic process from tryptophan [GO:1905012]; tryptophan catabolic process [GO:0006569]		negative regulation of quinolinate biosynthetic process [GO:1904985]; picolinic acid biosynthetic process [GO:1905004]; regulation of 'de novo' NAD biosynthetic process from tryptophan [GO:1905012]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	metal ion binding [GO:0046872]	aminocarboxymuconate-semialdehyde decarboxylase activity [GO:0001760]; hydrolase activity [GO:0016787]; zinc ion binding [GO:0008270]
d3hkfa1_d5n2fb1__1		Metazoa		Chordata		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		
d3hkfa2_d1cfta2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3hkna__d4xixb___1	Metazoa	Viridiplantae	Chordata	Chlorophyta	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3hkra2_d4l5ob2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d3hkra2_d6gssb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3hkrb2_d4zb8a2__1	Metazoa	Fungi	Chordata	Basidiomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	
d3hl2b__d5xmsc___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; transferase activity, transferring selenium-containing groups [GO:0016785]; tRNA binding [GO:0000049]; selenocysteine incorporation [GO:0001514]; selenocysteine metabolic process [GO:0016259]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	selenocysteine incorporation [GO:0001514]; selenocysteine metabolic process [GO:0016259]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		transferase activity, transferring selenium-containing groups [GO:0016785]; tRNA binding [GO:0000049]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d3hlhc__d2gvua___1	Metazoa	Metazoa	Mollusca	Mollusca	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]					calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]
d3hlid__d5xfea___1	Metazoa	Metazoa	Mollusca	Arthropoda	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	metal ion binding [GO:0046872]					calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	metal ion binding [GO:0046872]
d3hlta1_d3ij5c___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; dephosphorylation [GO:0016311]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	dephosphorylation [GO:0016311]	lipopolysaccharide biosynthetic process [GO:0009103]	extracellular exosome [GO:0070062]		enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d3hlxd1_d5ucaa___1		Metazoa	Proteobacteria	Chordata	pyrroloquinoline-quinone synthase activity [GO:0033732]; pyrroloquinoline quinone biosynthetic process [GO:0018189]	cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	pyrroloquinoline quinone biosynthetic process [GO:0018189]	cellular iron ion homeostasis [GO:0006879]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; iron ion homeostasis [GO:0055072]; neutrophil degranulation [GO:0043312]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	pyrroloquinoline-quinone synthase activity [GO:0033732]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d3hm3a__d5chwd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3hm3b__d5toga___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3hm3b__d5y3bc1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	axon terminus [GO:0043679]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]; actin binding [GO:0003779]; gamma-tubulin binding [GO:0043015]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein domain specific binding [GO:0019904]; canonical Wnt signaling pathway [GO:0060070]; cell proliferation in forebrain [GO:0021846]; cerebellar cortex development [GO:0021695]; cerebral cortex cell migration [GO:0021795]; cerebral cortex radially oriented cell migration [GO:0021799]; forebrain ventricular zone progenitor cell division [GO:0021869]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of axonogenesis [GO:0050772]; positive regulation of JNK cascade [GO:0046330]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microtubule cytoskeleton organization [GO:0070507]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	canonical Wnt signaling pathway [GO:0060070]; cell proliferation in forebrain [GO:0021846]; cerebellar cortex development [GO:0021695]; cerebral cortex cell migration [GO:0021795]; cerebral cortex radially oriented cell migration [GO:0021799]; forebrain ventricular zone progenitor cell division [GO:0021869]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of axonogenesis [GO:0050772]; positive regulation of JNK cascade [GO:0046330]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microtubule cytoskeleton organization [GO:0070507]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	axon terminus [GO:0043679]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	actin binding [GO:0003779]; gamma-tubulin binding [GO:0043015]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein domain specific binding [GO:0019904]
d3hm8a1_d1ijja2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3hm8a2_d1u6zb2__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	plasma membrane [GO:0005886]; exopolyphosphatase activity [GO:0004309]; identical protein binding [GO:0042802]; phosphorus metabolic process [GO:0006793]; polyphosphate catabolic process [GO:0006798]	canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	phosphorus metabolic process [GO:0006793]; polyphosphate catabolic process [GO:0006798]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]	exopolyphosphatase activity [GO:0004309]; identical protein binding [GO:0042802]
d3hm8b1_d3ldnb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3hmea__d3uv5a2__1	Metazoa	Metazoa	Chordata	Chordata	SWI/SNF complex [GO:0016514]; lysine-acetylated histone binding [GO:0070577]; nucleic acid binding [GO:0003676]; chromatin organization [GO:0006325]	MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]; ATP binding [GO:0005524]; histone acetyltransferase activity [GO:0004402]; kinase activity [GO:0016301]; lysine-acetylated histone binding [GO:0070577]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein heterodimerization activity [GO:0046982]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin conjugating enzyme activity [GO:0061631]; cell cycle [GO:0007049]; cellular response to ATP [GO:0071318]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA-templated transcription, initiation [GO:0006352]; midbrain development [GO:0030901]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of protein autoubiquitination [GO:1905524]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010768]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription initiation from RNA polymerase II promoter [GO:0060260]; regulation of transcription, DNA-templated [GO:0006355]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription factor catabolic process [GO:0036369]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	chromatin organization [GO:0006325]	cell cycle [GO:0007049]; cellular response to ATP [GO:0071318]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA-templated transcription, initiation [GO:0006352]; midbrain development [GO:0030901]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of protein autoubiquitination [GO:1905524]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010768]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription initiation from RNA polymerase II promoter [GO:0060260]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription factor catabolic process [GO:0036369]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	SWI/SNF complex [GO:0016514]	MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]	lysine-acetylated histone binding [GO:0070577]; nucleic acid binding [GO:0003676]	ATP binding [GO:0005524]; histone acetyltransferase activity [GO:0004402]; kinase activity [GO:0016301]; lysine-acetylated histone binding [GO:0070577]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein heterodimerization activity [GO:0046982]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin conjugating enzyme activity [GO:0061631]
d3hmgc__d4wswc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3hmge__d2wrbb1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3hmge__d3m5je___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3hmha1_d5pfva1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; transcription factor TFIID complex [GO:0005669]; histone acetyltransferase activity [GO:0004402]; lysine-acetylated histone binding [GO:0070577]; protein serine/threonine kinase activity [GO:0004674]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]; male meiotic nuclear division [GO:0007140]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	male meiotic nuclear division [GO:0007140]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleoplasm [GO:0005654]; transcription factor TFIID complex [GO:0005669]	nucleus [GO:0005634]	histone acetyltransferase activity [GO:0004402]; lysine-acetylated histone binding [GO:0070577]; protein serine/threonine kinase activity [GO:0004674]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d3hmua1_d5hdmb___1		Viridiplantae	Proteobacteria	Streptophyta	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; plastid [GO:0009536]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]		chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]		apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; plastid [GO:0009536]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d3hmub1_d2ogaa___1			Proteobacteria	Actinobacteria	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; macrolide biosynthetic process [GO:0033068]		macrolide biosynthetic process [GO:0033068]			pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d3hmwl1_d3bz4e2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3hmwl2_d2uwef1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3hmya2_d3zc8a___1		Viridiplantae	Firmicutes	Streptophyta	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	endopeptidase inhibitor activity [GO:0004866]	negative regulation of neurotransmitter secretion [GO:0046929]		clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	endopeptidase inhibitor activity [GO:0004866]
d3hn1a2_d1g9ca2__1			Firmicutes	Firmicutes	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d3hn3a2_d3mv014__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	beta-galactosidase complex [GO:0009341]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3hn3a2_d4duva4__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	beta-galactosidase complex [GO:0009341]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3hn3a3_d4duvb3__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	beta-galactosidase complex [GO:0009341]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3hn3b3_d2vota5__1	Metazoa		Chordata	Bacteroidetes	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]		beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	beta-mannosidase activity [GO:0004567]
d3hn3d2_d2vqua1__1	Metazoa		Chordata	Bacteroidetes	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]		beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	beta-mannosidase activity [GO:0004567]
d3hn3d3_d1kr0a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	vacuole [GO:0005773]; chitinase activity [GO:0004568]; lysozyme activity [GO:0003796]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	vacuole [GO:0005773]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	chitinase activity [GO:0004568]; lysozyme activity [GO:0003796]
d3hn3e2_d2x05a2__1	Metazoa		Chordata	Actinobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	extracellular region [GO:0005576]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3hn3e2_d4duwd2__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	beta-galactosidase complex [GO:0009341]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3hn6a1_d5e5hb2__1			Spirochaetes	Proteobacteria	cytosol [GO:0005829]; glucosamine-6-phosphate deaminase activity [GO:0004342]; carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylneuraminate catabolic process [GO:0019262]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylneuraminate catabolic process [GO:0019262]	acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	cytosol [GO:0005829]		glucosamine-6-phosphate deaminase activity [GO:0004342]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d3hn6d1_d2ahwc2__1			Spirochaetes	Proteobacteria	cytosol [GO:0005829]; glucosamine-6-phosphate deaminase activity [GO:0004342]; carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylneuraminate catabolic process [GO:0019262]	acetate CoA-transferase activity [GO:0008775]; ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]	carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylneuraminate catabolic process [GO:0019262]	ketone body catabolic process [GO:0046952]; protein homotetramerization [GO:0051289]; short-chain fatty acid metabolic process [GO:0046459]	cytosol [GO:0005829]		glucosamine-6-phosphate deaminase activity [GO:0004342]	acetate CoA-transferase activity [GO:0008775]
d3hn9a__d1ufga1__1		Metazoa		Chordata		cytosol [GO:0005829]; lamin filament [GO:0005638]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; identical protein binding [GO:0042802]; protein phosphatase 1 binding [GO:0008157]; cellular protein localization [GO:0034613]; cellular response to hypoxia [GO:0071456]; establishment of cell polarity [GO:0030010]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; muscle organ development [GO:0007517]; negative regulation of adipose tissue development [GO:1904178]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of mesenchymal cell proliferation [GO:0072201]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; nuclear envelope organization [GO:0006998]; nucleus organization [GO:0006997]; positive regulation of cell aging [GO:0090343]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K9 trimethylation [GO:1900114]; positive regulation of osteoblast differentiation [GO:0045669]; protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504]; regulation of cell migration [GO:0030334]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; ventricular cardiac muscle cell development [GO:0055015]		cellular protein localization [GO:0034613]; cellular response to hypoxia [GO:0071456]; establishment of cell polarity [GO:0030010]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; muscle organ development [GO:0007517]; negative regulation of adipose tissue development [GO:1904178]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of mesenchymal cell proliferation [GO:0072201]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; nuclear envelope organization [GO:0006998]; nucleus organization [GO:0006997]; positive regulation of cell aging [GO:0090343]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K9 trimethylation [GO:1900114]; positive regulation of osteoblast differentiation [GO:0045669]; protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504]; regulation of cell migration [GO:0030334]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; ventricular cardiac muscle cell development [GO:0055015]		cytosol [GO:0005829]; lamin filament [GO:0005638]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]		identical protein binding [GO:0042802]; protein phosphatase 1 binding [GO:0008157]
d3hnbm__d3i97b___1	Metazoa	Metazoa	Chordata	Chordata	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]; coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]	copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]	coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d3hnbm__d4omcf2__1	Metazoa	Metazoa	Chordata	Chordata	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d3hnia__d3m79d___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3hnib__d2ylga___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3hnic__d1nbbb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3hnid__d5jt4a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3hnig__d2qlac___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3hnih__d5jsla___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3hnja__d3hnka___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3hnjb__d1jafa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3hnjd__d3fooe___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3hnkb__d1e84a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3hnsl1_d4dvrl1__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d3hntl1_d4rfef1__1												
d3hntl2_d4tvpl2__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d3hnvl2_d4l29k2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3hnza2_d1m3kc2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3ho2a2_d4o99a2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3ho9a2_d1m3ka2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3hoaa__d1pwva1__1			Deinococcus-Thermus	Firmicutes	metal ion binding [GO:0046872]; metallocarboxypeptidase activity [GO:0004181]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]		negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metallocarboxypeptidase activity [GO:0004181]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d3hobm__d2eiba2__1	Metazoa	Fungi	Chordata	Ascomycota	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]		COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	extracellular region [GO:0005576]	copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]
d3hobm__d5ijrb1__1	Metazoa	Metazoa	Chordata	Chordata	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]; coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]	copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]	coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d3hoca2_d1dxxc1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	cell [GO:0005623]; cell surface [GO:0009986]; cell-substrate junction [GO:0030055]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]; actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein localization [GO:0034613]; cellular protein-containing complex assembly [GO:0034622]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle contraction [GO:0060048]; cellular protein-containing complex assembly [GO:0034622]; cellular protein localization [GO:0034613]; motile cilium assembly [GO:0044458]; muscle cell cellular homeostasis [GO:0046716]; muscle fiber development [GO:0048747]; muscle filament sliding [GO:0030049]; muscle organ development [GO:0007517]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; peptide biosynthetic process [GO:0043043]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cellular response to growth factor stimulus [GO:0090287]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of skeletal muscle contraction [GO:0014819]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of voltage-gated calcium channel activity [GO:1901385]; response to muscle stretch [GO:0035994]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	cell [GO:0005623]; cell-substrate junction [GO:0030055]; cell surface [GO:0009986]; costamere [GO:0043034]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dystrophin-associated glycoprotein complex [GO:0016010]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; synapse [GO:0045202]; syntrophin complex [GO:0016013]; Z disc [GO:0030018]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	actin binding [GO:0003779]; dystroglycan binding [GO:0002162]; myosin binding [GO:0017022]; nitric-oxide synthase binding [GO:0050998]; structural constituent of cytoskeleton [GO:0005200]; structural constituent of muscle [GO:0008307]; vinculin binding [GO:0017166]; zinc ion binding [GO:0008270]
d3hoda__d1s0za___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]; activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	cell [GO:0005623]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]; calcitriol binding [GO:1902098]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; lithocholic acid binding [GO:1902121]; lithocholic acid receptor activity [GO:0038186]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; vitamin D binding [GO:0005499]; zinc ion binding [GO:0008270]; animal organ morphogenesis [GO:0009887]; bile acid signaling pathway [GO:0038183]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cell morphogenesis [GO:0000902]; cellular calcium ion homeostasis [GO:0006874]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; decidualization [GO:0046697]; intestinal absorption [GO:0050892]; lactation [GO:0007595]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; mammary gland branching involved in pregnancy [GO:0060745]; multicellular organism development [GO:0007275]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process involved in mammary gland involution [GO:0060058]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vitamin D 24-hydroxylase activity [GO:0010980]; regulation of calcidiol 1-monooxygenase activity [GO:0060558]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; transcription initiation from RNA polymerase II promoter [GO:0006367]; vitamin D metabolic process [GO:0042359]; vitamin D receptor signaling pathway [GO:0070561]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; animal organ regeneration [GO:0031100]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cellular response to hyperoxia [GO:0071455]; cellular response to insulin stimulus [GO:0032869]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin E [GO:0071306]; epithelial cell differentiation [GO:0030855]; fatty acid metabolic process [GO:0006631]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; long-chain fatty acid transport [GO:0015909]; low-density lipoprotein particle receptor biosynthetic process [GO:0045713]; macrophage derived foam cell differentiation [GO:0010742]; monocyte differentiation [GO:0030224]; multicellular organism development [GO:0007275]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell growth [GO:0030308]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pancreatic stellate cell proliferation [GO:2000230]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; peroxisome proliferator activated receptor signaling pathway [GO:0035357]; placenta development [GO:0001890]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of blood pressure [GO:0008217]; regulation of cholesterol transporter activity [GO:0060694]; regulation of circadian rhythm [GO:0042752]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in cell fate commitment [GO:0060850]; response to caffeine [GO:0031000]; response to cold [GO:0009409]; response to estrogen [GO:0043627]; response to immobilization stress [GO:0035902]; response to lipid [GO:0033993]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to nutrient [GO:0007584]; response to retinoic acid [GO:0032526]; response to starvation [GO:0042594]; response to vitamin A [GO:0033189]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]; white fat cell differentiation [GO:0050872]	animal organ morphogenesis [GO:0009887]; bile acid signaling pathway [GO:0038183]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cell morphogenesis [GO:0000902]; cellular calcium ion homeostasis [GO:0006874]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; decidualization [GO:0046697]; intestinal absorption [GO:0050892]; lactation [GO:0007595]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; mammary gland branching involved in pregnancy [GO:0060745]; multicellular organism development [GO:0007275]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process involved in mammary gland involution [GO:0060058]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vitamin D 24-hydroxylase activity [GO:0010980]; regulation of calcidiol 1-monooxygenase activity [GO:0060558]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; transcription initiation from RNA polymerase II promoter [GO:0006367]; vitamin D metabolic process [GO:0042359]; vitamin D receptor signaling pathway [GO:0070561]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]	cell [GO:0005623]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; receptor complex [GO:0043235]; RNA polymerase II transcription factor complex [GO:0090575]	activating transcription factor binding [GO:0033613]; alpha-actinin binding [GO:0051393]; arachidonic acid binding [GO:0050544]; chromatin binding [GO:0003682]; DBD domain binding [GO:0050692]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; drug binding [GO:0008144]; E-box binding [GO:0070888]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; LBD domain binding [GO:0050693]; lipid binding [GO:0008289]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; peptide binding [GO:0042277]; prostaglandin receptor activity [GO:0004955]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II repressing transcription factor binding [GO:0001103]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	calcitriol binding [GO:1902098]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; lithocholic acid binding [GO:1902121]; lithocholic acid receptor activity [GO:0038186]; nuclear receptor activity [GO:0004879]; nuclear receptor transcription coactivator activity [GO:0030374]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; signaling receptor activity [GO:0038023]; steroid hormone receptor activity [GO:0003707]; transcription factor binding [GO:0008134]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; vitamin D binding [GO:0005499]; zinc ion binding [GO:0008270]
d3hopb2_d1p2xa___1	Metazoa	Fungi	Chordata	Ascomycota	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actomyosin contractile ring [GO:0005826]; actomyosin contractile ring, proximal layer [GO:0120104]; cytoplasm [GO:0005737]; medial cortical node [GO:0071341]; mitotic actomyosin contractile ring [GO:0110085]; mitotic spindle pole body [GO:0044732]; nuclear envelope [GO:0005635]; spindle pole body [GO:0005816]; actin filament binding [GO:0051015]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; actin filament bundle assembly [GO:0051017]; actin filament bundle convergence involved in mitotic contractile ring assembly [GO:1903478]; division septum assembly [GO:0000917]; mitotic actomyosin contractile ring assembly [GO:1903475]; mitotic actomyosin contractile ring assembly actin filament organization [GO:1903479]; mitotic actomyosin contractile ring localization [GO:1902405]; mitotic contractile ring actin filament bundle assembly [GO:1903477]; negative regulation of actin filament depolymerization [GO:0030835]; positive regulation of actin filament polymerization [GO:0030838]; protein localization to cell division site involved in mitotic actomyosin contractile ring assembly [GO:1903476]; protein localization to medial cortex [GO:0071574]; signal transduction [GO:0007165]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actin filament bundle assembly [GO:0051017]; actin filament bundle convergence involved in mitotic contractile ring assembly [GO:1903478]; division septum assembly [GO:0000917]; mitotic actomyosin contractile ring assembly [GO:1903475]; mitotic actomyosin contractile ring assembly actin filament organization [GO:1903479]; mitotic actomyosin contractile ring localization [GO:1902405]; mitotic contractile ring actin filament bundle assembly [GO:1903477]; negative regulation of actin filament depolymerization [GO:0030835]; positive regulation of actin filament polymerization [GO:0030838]; protein localization to cell division site involved in mitotic actomyosin contractile ring assembly [GO:1903476]; protein localization to medial cortex [GO:0071574]; signal transduction [GO:0007165]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	actomyosin contractile ring [GO:0005826]; actomyosin contractile ring, proximal layer [GO:0120104]; cytoplasm [GO:0005737]; medial cortical node [GO:0071341]; mitotic actomyosin contractile ring [GO:0110085]; mitotic spindle pole body [GO:0044732]; nuclear envelope [GO:0005635]; spindle pole body [GO:0005816]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	actin filament binding [GO:0051015]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]
d3hopb2_d1wkub1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]; focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	focal adhesion assembly [GO:0048041]; muscle filament sliding [GO:0030049]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	actin filament [GO:0005884]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; pseudopodium [GO:0031143]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	actin binding [GO:0003779]; calcium ion binding [GO:0005509]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; structural constituent of muscle [GO:0008307]
d3hora2_d3co1a1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; midbody [GO:0030496]; mitotic spindle astral microtubule end [GO:1905721]; perinuclear region of cytoplasm [GO:0048471]; spindle midzone [GO:0051233]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; cell division [GO:0051301]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	cell division [GO:0051301]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; midbody [GO:0030496]; mitotic spindle astral microtubule end [GO:1905721]; perinuclear region of cytoplasm [GO:0048471]; spindle midzone [GO:0051233]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]
d3horb2_d1wyla1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; hippocampal mossy fiber expansion [GO:1990026]; intercellular bridge [GO:0045171]; intermediate filament [GO:0005882]; midbody [GO:0030496]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; SH3 domain binding [GO:0017124]; actin filament bundle assembly [GO:0051017]; actin filament depolymerization [GO:0030042]; blood coagulation [GO:0007596]; cytoskeleton organization [GO:0007010]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of protein phosphorylation [GO:0001933]; oxidation-reduction process [GO:0055114]; regulation of regulated secretory pathway [GO:1903305]; signal transduction [GO:0007165]; sulfur oxidation [GO:0019417]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	actin filament bundle assembly [GO:0051017]; actin filament depolymerization [GO:0030042]; blood coagulation [GO:0007596]; cytoskeleton organization [GO:0007010]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of protein phosphorylation [GO:0001933]; oxidation-reduction process [GO:0055114]; regulation of regulated secretory pathway [GO:1903305]; signal transduction [GO:0007165]; sulfur oxidation [GO:0019417]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; hippocampal mossy fiber expansion [GO:1990026]; intercellular bridge [GO:0045171]; intermediate filament [GO:0005882]; midbody [GO:0030496]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; protein kinase binding [GO:0019901]; Rab GTPase binding [GO:0017137]; SH3 domain binding [GO:0017124]
d3hpea__d1y0gc___1			Proteobacteria	Proteobacteria		periplasmic space [GO:0042597]				periplasmic space [GO:0042597]		
d3hpeb__d5ixgc___1			Proteobacteria	Proteobacteria								
d3hpfa2_d1ebgb1__1		Fungi	Firmicutes	Ascomycota	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3hpia__d3ppna___1			Proteobacteria	Firmicutes	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; amino acid transport [GO:0006865]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	amino acid transport [GO:0006865]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	transmembrane transporter activity [GO:0022857]
d3hpje1_d2edja1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	axolemma [GO:0030673]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; cellular response to hormone stimulus [GO:0032870]; central nervous system development [GO:0007417]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; negative regulation of synapse assembly [GO:0051964]; olfactory bulb interneuron development [GO:0021891]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; pulmonary valve morphogenesis [GO:0003184]; retinal ganglion cell axon guidance [GO:0031290]; spinal cord development [GO:0021510]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; apoptotic process involved in luteolysis [GO:0061364]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; cellular response to hormone stimulus [GO:0032870]; central nervous system development [GO:0007417]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; negative regulation of synapse assembly [GO:0051964]; olfactory bulb interneuron development [GO:0021891]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; pulmonary valve morphogenesis [GO:0003184]; retinal ganglion cell axon guidance [GO:0031290]; spinal cord development [GO:0021510]; ureteric bud development [GO:0001657]; ventricular septum morphogenesis [GO:0060412]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	axolemma [GO:0030673]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]
d3hpna__d3t2pa1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	lactose catabolic process [GO:0005990]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	beta-galactosidase complex [GO:0009341]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3hpnb__d3i97a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]; coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d3hpnd__d1jyzl3__1	Metazoa		Chordata		cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]		activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]		cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]		ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	
d3hpnd__d4arxd3__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	sporulation resulting in formation of a cellular spore [GO:0030435]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]		ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d3hpvb1_d3bzaa1__1			Proteobacteria	Actinobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3hpvc1_d2ei2a2__1			Proteobacteria	Proteobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	1,2-dihydroxynaphthalene dioxygenase activity [GO:0018554]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; naphthalene catabolic process [GO:1901170]	aromatic compound catabolic process [GO:0019439]	naphthalene catabolic process [GO:1901170]			catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	1,2-dihydroxynaphthalene dioxygenase activity [GO:0018554]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d3hpvc2_d5ec3a1__1		Metazoa	Proteobacteria	Chordata	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; 4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	aromatic compound catabolic process [GO:0019439]	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]
d3hpvd1_d3hpyb2__1			Proteobacteria	Proteobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]
d3hpvd2_d1f1yb1__1			Proteobacteria		catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]				catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	
d3hpyb1_d2ig9d2__1			Proteobacteria	Actinobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3hpyb2_d1q0ca1__1			Proteobacteria	Actinobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3hpyc2_d4z6zb1__1			Proteobacteria	Actinobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3hpyd1_d5trxb2__1			Proteobacteria	Actinobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3hpyd2_d1cjxd1__1			Proteobacteria	Proteobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	aromatic compound catabolic process [GO:0019439]	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]			catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]
d3hq0a1_d1f1va1__1			Proteobacteria	Actinobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3hq0a2_d2igaa1__1			Proteobacteria	Actinobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3hq0b1_d3eckb2__1			Proteobacteria	Actinobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3hq0c1_d4ghga1__1			Proteobacteria	Actinobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3hq0c2_d1cjxa1__1			Proteobacteria	Proteobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	aromatic compound catabolic process [GO:0019439]	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]			catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	4-hydroxyphenylpyruvate dioxygenase activity [GO:0003868]; metal ion binding [GO:0046872]
d3hq0d1_d3ojja1__1			Proteobacteria	Actinobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3hq0d2_d4z6zc2__1			Proteobacteria	Actinobacteria	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]				catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3hq2a__d4hx3i1__1			Firmicutes	Actinobacteria	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	serine-type endopeptidase inhibitor activity [GO:0004867]	proteolysis [GO:0006508]				metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	serine-type endopeptidase inhibitor activity [GO:0004867]
d3hqpg3_d1liud6__1					ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]						ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	
d3hqpi3_d2vgfa3__1		Metazoa		Chordata	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]		ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to insulin stimulus [GO:0032869]; glycolytic process [GO:0006096]; pyruvate biosynthetic process [GO:0042866]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lithium ion [GO:0010226]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d3hqpp3_d1a5ub3__1		Metazoa		Chordata	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]		positive regulation of sprouting angiogenesis [GO:1903672]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d3hr1a__d5axpb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3hr4f__d1kk8c___1	Metazoa	Metazoa	Chordata	Mollusca	cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; arginine binding [GO:0034618]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin binding [GO:0034617]; arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; circadian rhythm [GO:0007623]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of leukocyte mediated cytotoxicity [GO:0001912]; prostaglandin secretion [GO:0032310]; protein targeting to peroxisome [GO:0006625]; regulation of cell population proliferation [GO:0042127]; regulation of cellular respiration [GO:0043457]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; circadian rhythm [GO:0007623]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of leukocyte mediated cytotoxicity [GO:0001912]; prostaglandin secretion [GO:0032310]; protein targeting to peroxisome [GO:0006625]; regulation of cell population proliferation [GO:0042127]; regulation of cellular respiration [GO:0043457]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]		cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	arginine binding [GO:0034618]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin binding [GO:0034617]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]
d3hr4f__d1rwyc___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; arginine binding [GO:0034618]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin binding [GO:0034617]; arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; circadian rhythm [GO:0007623]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of leukocyte mediated cytotoxicity [GO:0001912]; prostaglandin secretion [GO:0032310]; protein targeting to peroxisome [GO:0006625]; regulation of cell population proliferation [GO:0042127]; regulation of cellular respiration [GO:0043457]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cochlea development [GO:0090102]	arginine catabolic process [GO:0006527]; cell redox homeostasis [GO:0045454]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; circadian rhythm [GO:0007623]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response in mucosa [GO:0002227]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of leukocyte mediated cytotoxicity [GO:0001912]; prostaglandin secretion [GO:0032310]; protein targeting to peroxisome [GO:0006625]; regulation of cell population proliferation [GO:0042127]; regulation of cellular respiration [GO:0043457]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	cochlea development [GO:0090102]	cell [GO:0005623]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]	arginine binding [GO:0034618]; calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin binding [GO:0034617]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d3hraa1_d1mx2a___1		Metazoa	Firmicutes	Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]; cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of phosphorylation [GO:0042326]; oligodendrocyte differentiation [GO:0048709]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]		cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of phosphorylation [GO:0042326]; oligodendrocyte differentiation [GO:0048709]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]
d3hrdd2_d2w3re2__1			Firmicutes	Proteobacteria	FAD binding [GO:0071949]; nicotinate dehydrogenase activity [GO:0050138]; cofactor catabolic process [GO:0051187]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cofactor catabolic process [GO:0051187]				FAD binding [GO:0071949]; nicotinate dehydrogenase activity [GO:0050138]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3hrdh1_d1vdva2__1		Metazoa	Firmicutes	Chordata	FAD binding [GO:0071949]; nicotinate dehydrogenase activity [GO:0050138]; cofactor catabolic process [GO:0051187]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cofactor catabolic process [GO:0051187]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	FAD binding [GO:0071949]; nicotinate dehydrogenase activity [GO:0050138]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d3hrdh2_d2w3se2__1			Firmicutes	Proteobacteria	FAD binding [GO:0071949]; nicotinate dehydrogenase activity [GO:0050138]; cofactor catabolic process [GO:0051187]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	cofactor catabolic process [GO:0051187]				FAD binding [GO:0071949]; nicotinate dehydrogenase activity [GO:0050138]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3hrhb__d1dqzb___1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	cell wall [GO:0005618]; extracellular region [GO:0005576]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]	cell wall [GO:0005618]; extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]	diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]
d3hrwa__d1uc3e___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; myelin sheath [GO:0043209]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; erythrocyte development [GO:0048821]; hemopoiesis [GO:0030097]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; regulation of eIF2 alpha phosphorylation by heme [GO:0010999]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; erythrocyte development [GO:0048821]; hemopoiesis [GO:0030097]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; regulation of eIF2 alpha phosphorylation by heme [GO:0010999]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; myelin sheath [GO:0043209]		heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3hrxa__d2vx2b___1		Metazoa	Deinococcus-Thermus	Chordata	catalytic activity [GO:0003824]	mitochondrion [GO:0005739]; catalytic activity [GO:0003824]; fatty acid metabolic process [GO:0006631]		fatty acid metabolic process [GO:0006631]		mitochondrion [GO:0005739]	catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d3hrxb__d2vx2f___1		Metazoa	Deinococcus-Thermus	Chordata	catalytic activity [GO:0003824]	mitochondrion [GO:0005739]; catalytic activity [GO:0003824]; fatty acid metabolic process [GO:0006631]		fatty acid metabolic process [GO:0006631]		mitochondrion [GO:0005739]	catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d3hsbd__d3vu3h___1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; RNA binding [GO:0003723]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	RNA binding [GO:0003723]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3hsca1_d3r9pa1__1	Metazoa		Chordata	Actinobacteria	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]
d3hsca2_d3bf3b1__1	Metazoa		Chordata	Thermotogae	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	coenzyme A biosynthetic process [GO:0015937]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d3hsdb__d1ru1b___1			Proteobacteria	Proteobacteria	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]			2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]
d3hsqc__d1hv9a1__1			Spirochaetes	Proteobacteria	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	lipid A biosynthetic process [GO:0009245]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d3hsqc__d4g3qa2__1			Spirochaetes	Actinobacteria	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]; adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	lipid A biosynthetic process [GO:0009245]	adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]
d3hsrb1_d5eria1__1			Firmicutes	Firmicutes	DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]					DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3hsta1_d2xxha1__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3hsta1_d4pdha___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	outer membrane-bounded periplasmic space [GO:0030288]; transmembrane transport [GO:0055085]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	
d3hsyb__d1lbhd___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	negative regulation of transcription, DNA-templated [GO:0045892]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cytosol [GO:0005829]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]
d3ht6a__d4rlma___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3htba__d3d9ac___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3htfa__d1tdya___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3htga__d2rb1x___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3htza1_d2dveb1__1			Aquificae	Euryarchaeota	cytosol [GO:0005829]; alanine-tRNA ligase activity [GO:0004813]; amino acid binding [GO:0016597]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; alanyl-tRNA aminoacylation [GO:0006419]; tRNA modification [GO:0006400]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	alanyl-tRNA aminoacylation [GO:0006419]; tRNA modification [GO:0006400]	cellular protein modification process [GO:0006464]	cytosol [GO:0005829]		alanine-tRNA ligase activity [GO:0004813]; amino acid binding [GO:0016597]; aminoacyl-tRNA editing activity [GO:0002161]; ATP binding [GO:0005524]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d3hu1a1_d1g8ka1__1	Metazoa		Chordata	Proteobacteria	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]
d3hu1a3_d1iqpc2__1	Metazoa		Chordata	Euryarchaeota	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; four-way junction helicase activity [GO:0009378]
d3hu1c3_d1ny6c___1	Metazoa		Chordata	Aquificae	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d3hu1e1_d1pyu.2__1	Metazoa		Chordata	Proteobacteria	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	cytosol [GO:0005829]; aspartate 1-decarboxylase activity [GO:0004068]; alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	cytosol [GO:0005829]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	aspartate 1-decarboxylase activity [GO:0004068]
d3hu1e2_d4ko8b2__1	Metazoa	Metazoa	Chordata	Chordata	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d3hu1f1_d1ti6i1__1	Metazoa		Chordata		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	
d3hu2b1_d3hu1d1__1	Metazoa	Metazoa	Chordata	Chordata	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d3hu2c1_d4kodb1__1	Metazoa	Metazoa	Chordata	Chordata	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d3hu2d1_d1h5nc1__1	Metazoa		Chordata	Proteobacteria	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	periplasmic space [GO:0042597]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]
d3hu2e1_d2napa1__1	Metazoa		Chordata	Proteobacteria	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	periplasmic space [GO:0042597]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; nitrate assimilation [GO:0042128]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	periplasmic space [GO:0042597]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase (cytochrome) activity [GO:0050140]; nitrate reductase activity [GO:0008940]
d3hu3a2_d1s3sa3__1	Metazoa	Metazoa	Chordata	Chordata	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d3hu3b1_d1ti4k1__1	Metazoa		Chordata		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]		ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	
d3hu3b2_d2pjhb2__1	Metazoa	Metazoa	Chordata	Chordata	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d3hu8a__d3lyoa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3huaa__d4h9ea___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3huda2_d2p9ga1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	L-serine biosynthetic process [GO:0006564]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]
d3hudb2_d4ag3b___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3hujb__d1q1jl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d3hujd__d3g5xc2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3hujd__d4aiza___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3hujg1_d3w2dl2__1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d3hupa__d2py2c___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]; cellular response to drug [GO:0035690]	metal ion binding [GO:0046872]	cellular response to drug [GO:0035690]		external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; protein-containing complex [GO:0032991]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; transmembrane signaling receptor activity [GO:0004888]	metal ion binding [GO:0046872]
d3hvha__d3q7ea___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytosol [GO:0005829]; membrane [GO:0016020]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; [cytochrome c]-arginine N-methyltransferase activity [GO:0016275]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; histone-arginine N-methyltransferase activity [GO:0008469]; identical protein binding [GO:0042802]; methyl-CpG binding [GO:0008327]; protein methyltransferase activity [GO:0008276]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; snoRNP binding [GO:0030519]; histone H4-R3 methylation [GO:0043985]; liver regeneration [GO:0097421]; negative regulation of megakaryocyte differentiation [GO:0045653]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; peptidyl-arginine omega-N-methylation [GO:0035247]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hemoglobin biosynthetic process [GO:0046985]; positive regulation of p38MAPK cascade [GO:1900745]; protein homooligomerization [GO:0051260]; protein methylation [GO:0006479]; regulation of megakaryocyte differentiation [GO:0045652]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	histone H4-R3 methylation [GO:0043985]; liver regeneration [GO:0097421]; negative regulation of megakaryocyte differentiation [GO:0045653]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; peptidyl-arginine omega-N-methylation [GO:0035247]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hemoglobin biosynthetic process [GO:0046985]; positive regulation of p38MAPK cascade [GO:1900745]; protein homooligomerization [GO:0051260]; protein methylation [GO:0006479]; regulation of megakaryocyte differentiation [GO:0045652]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	cytosol [GO:0005829]; membrane [GO:0016020]; methylosome [GO:0034709]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	[cytochrome c]-arginine N-methyltransferase activity [GO:0016275]; histone-arginine N-methyltransferase activity [GO:0008469]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; identical protein binding [GO:0042802]; methyl-CpG binding [GO:0008327]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; protein methyltransferase activity [GO:0008276]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; snoRNP binding [GO:0030519]
d3hvha__d5p91a___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d3hvja__d4gf5b___1	Metazoa		Chordata	Actinobacteria	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	O-methyltransferase activity [GO:0008171]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]		catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	O-methyltransferase activity [GO:0008171]
d3hvka__d3ndja___1	Metazoa		Chordata	Actinobacteria	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]		catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]
d3hvka__d5k0gb___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d3hvma__d4e4jc___1			Proteobacteria	Tenericutes	protein-arginine deiminase activity [GO:0004668]; putrescine biosynthetic process [GO:0009446]	cytoplasm [GO:0005737]; arginine deiminase activity [GO:0016990]; arginine catabolic process to ornithine [GO:0019547]	putrescine biosynthetic process [GO:0009446]	arginine catabolic process to ornithine [GO:0019547]		cytoplasm [GO:0005737]	protein-arginine deiminase activity [GO:0004668]	arginine deiminase activity [GO:0016990]
d3hvqb__d3h64d___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]
d3hvsb__d3tjba___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d3hvsb__d5hwlb1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]
d3hvub1_d5eswa1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; nucleoside metabolic process [GO:0009116]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]		guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]
d3hvud1_d4ohce___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	magnesium ion binding [GO:0000287]; orotate phosphoribosyltransferase activity [GO:0004588]; 'de novo' UMP biosynthetic process [GO:0044205]; nucleoside metabolic process [GO:0009116]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	'de novo' UMP biosynthetic process [GO:0044205]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]		guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	magnesium ion binding [GO:0000287]; orotate phosphoribosyltransferase activity [GO:0004588]
d3hvxa__d1s3aa1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex I [GO:0005747]; NADH dehydrogenase (ubiquinone) activity [GO:0008137]; blastocyst hatching [GO:0001835]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	blastocyst hatching [GO:0001835]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex I [GO:0005747]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]	NADH dehydrogenase (ubiquinone) activity [GO:0008137]
d3hvxb__d1usba2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3hvxc__d2eiqb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d3hw7b__d2jlpd___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; heparin binding [GO:0008201]; superoxide dismutase activity [GO:0004784]; cellular response to oxidative stress [GO:0034599]; removal of superoxide radicals [GO:0019430]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	cellular response to oxidative stress [GO:0034599]; removal of superoxide radicals [GO:0019430]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; heparin binding [GO:0008201]; superoxide dismutase activity [GO:0004784]
d3hw8a1_d4iqva1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3hwea__d1hn2a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	extracellular region [GO:0005576]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	small molecule binding [GO:0036094]
d3hwea__d4i9sa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3hwgc__d3i17a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3hx2c1_d1z6ow___1		Metazoa		Arthropoda		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3hx2c1_d5goum___1		Metazoa		Chordata		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3hx2d__d1r65b___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3hx2f__d2ux1j___1				Firmicutes		cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d3hx2f__d4tods___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3hx2g__d4cmys___1				Chlorobi		cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]
d3hx2k1_d4tofb___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3hx2m1_d3oj5d___1				Actinobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]
d3hx2p__d3a68s___1		Viridiplantae		Streptophyta		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3hx2v__d3e1jc___1				Proteobacteria		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3hx2v__d5l8bp___1				Proteobacteria		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d3hx2w__d2v8ua___1				Deinococcus-Thermus		catalase activity [GO:0004096]; metal ion binding [GO:0046872]						catalase activity [GO:0004096]; metal ion binding [GO:0046872]
d3hx5a1_d5up9d___1		Metazoa		Chordata		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3hx5b1_d4todn___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3hx5d1_d4toaa___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3hx5f__d1oq7e___1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		chloroplast [GO:0009507]		acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d3hx5i__d1pfra___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3hx5j__d4cmyc___1				Chlorobi		cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]
d3hx5m__d1fz6b___1				Proteobacteria		metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]		cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]				metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3hx5o__d1bfrh___1				Proteobacteria		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3hx5q__d5d8yn___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3hx5r1_d2z6mf___1		Metazoa		Chordata		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3hx5s1_d1uzrb___1				Actinobacteria		ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		ribonucleoside-diphosphate reductase complex [GO:0005971]		metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3hx5w__d3vpma1__1		Metazoa		Chordata		cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]		deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]		cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3hx5x__d1xu3d___1				Proteobacteria		metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]		cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]				metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3hx7b__d4toap___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3hx7e1_d4m35c___1				Actinobacteria		cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3hx7f__d4cybg___1				Actinobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3hx7g1_d2c41f___1				Cyanobacteria		cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3hx7i__d5d8ol___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3hx7j1_d2bkco___1				Firmicutes		cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3hx7j1_d2jd6c___1				Euryarchaeota		cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]
d3hx7k__d1nf4i___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3hx7l__d5lbha___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3hx7m__d3a9qe___1		Viridiplantae		Streptophyta		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]		cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3hx7n__d3fvba1__1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3hx7n__d3iseb___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3hx7r1_d5lbhb___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3hx7t__d2fkzf___1				Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3hx7v__d4cybi___1				Actinobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3hx7w__d1syya___1				Chlamydiae		ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		ribonucleoside-diphosphate reductase complex [GO:0005971]		metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3hx9b__d3mm3a___1		Fungi	Actinobacteria	Basidiomycota	cell wall [GO:0005618]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; heme catabolic process [GO:0042167]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme catabolic process [GO:0042167]		cell wall [GO:0005618]; plasma membrane [GO:0005886]		heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3hxna__d2c7jb___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3hxnc__d2uunt___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3hxsa__d1x9sb___1			Bacteroidetes	Proteobacteria	cell [GO:0005623]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d3hxsb__d4poka1__1		Metazoa	Bacteroidetes	Chordata	cell [GO:0005623]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d3hy2a__d5lola1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]; cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; glutathione binding [GO:0043295]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; positive regulation of salicylic acid mediated signaling pathway [GO:0080151]; protein glutathionylation [GO:0010731]	cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	positive regulation of salicylic acid mediated signaling pathway [GO:0080151]; protein glutathionylation [GO:0010731]	cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]	glutathione binding [GO:0043295]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]
d3hy2b__d1jlwb2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]; cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]	glutathione transferase activity [GO:0004364]	cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979]		cytosol [GO:0005829]		ATP binding [GO:0005524]; oxidoreductase activity, acting on a sulfur group of donors [GO:0016667]; sulfiredoxin activity [GO:0032542]	glutathione transferase activity [GO:0004364]
d3hy7a__d1ge7a___1	Metazoa	Fungi	Chordata	Basidiomycota	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]		collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3hy9a__d2wo9a___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3hyba1_d2z46a___1			Cyanobacteria	Cyanobacteria		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d3hybb1_d4gr2a___1		Viridiplantae	Cyanobacteria	Streptophyta		chloroplast thylakoid [GO:0009534]; protein folding chaperone [GO:0044183]; chaperone-mediated protein folding [GO:0061077]; response to cold [GO:0009409]; response to salt stress [GO:0009651]; response to water deprivation [GO:0009414]		chaperone-mediated protein folding [GO:0061077]; response to cold [GO:0009409]; response to salt stress [GO:0009651]; response to water deprivation [GO:0009414]		chloroplast thylakoid [GO:0009534]		protein folding chaperone [GO:0044183]
d3hycb__d4hgoa___1			Proteobacteria	Bacteroidetes	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]			3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d3hycd__d1fezc___1			Proteobacteria	Firmicutes	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]	lipopolysaccharide biosynthetic process [GO:0009103]	organic phosphonate catabolic process [GO:0019700]			3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]
d3hycf__d4knwa___1		Metazoa	Proteobacteria	Chordata	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]; N-acylneuraminate-9-phosphatase activity [GO:0050124]; carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine biosynthetic process [GO:0006045]; N-acetylneuraminate biosynthetic process [GO:0046380]	lipopolysaccharide biosynthetic process [GO:0009103]	carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine biosynthetic process [GO:0006045]; N-acetylneuraminate biosynthetic process [GO:0046380]		cytosol [GO:0005829]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	N-acylneuraminate-9-phosphatase activity [GO:0050124]
d3hycg__d4umfa___1			Proteobacteria	Proteobacteria	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]			3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d3hye2__d1q5qi___1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3hyed__d4q1sa___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3hyei__d4qz2a___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3hyen__d1vsyb___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	
d3hyep__d4qluv___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3hyeq__d4no9t___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3hypa__d3dyrb___1			Bacteroidetes	Proteobacteria	cell [GO:0005623]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d3hypb__d3tjfe___1		Metazoa	Bacteroidetes	Chordata	cell [GO:0005623]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d3hyub__d1nwid___1	Metazoa	Metazoa	Chordata	Mollusca	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3hz2c__d1ytqa1__1		Metazoa	Euryarchaeota	Chordata	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; structural molecule activity [GO:0005198]; lens development in camera-type eye [GO:0002088]; response to stimulus [GO:0050896]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; response to stimulus [GO:0050896]; visual perception [GO:0007601]			metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; structural molecule activity [GO:0005198]
d3hz8a__d2f8ab___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; SH3 domain binding [GO:0017124]; angiogenesis involved in wound healing [GO:0060055]; blood vessel endothelial cell migration [GO:0043534]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; endothelial cell development [GO:0001885]; fat cell differentiation [GO:0045444]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide catabolic process [GO:0042744]; interaction with symbiont [GO:0051702]; lipoxygenase pathway [GO:0019372]; myoblast proliferation [GO:0051450]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of supramolecular fiber organization [GO:1902905]; protein oxidation [GO:0018158]; purine nucleotide catabolic process [GO:0006195]; regulation of gene expression, epigenetic [GO:0040029]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of proteasomal protein catabolic process [GO:0061136]; response to gamma radiation [GO:0010332]; response to hydrogen peroxide [GO:0042542]; response to hydroperoxide [GO:0033194]; response to selenium ion [GO:0010269]; response to symbiotic bacterium [GO:0009609]; response to xenobiotic stimulus [GO:0009410]; sensory perception of sound [GO:0007605]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue regeneration [GO:0043403]; temperature homeostasis [GO:0001659]; triglyceride metabolic process [GO:0006641]; UV protection [GO:0009650]; vasodilation [GO:0042311]	cell redox homeostasis [GO:0045454]	angiogenesis involved in wound healing [GO:0060055]; blood vessel endothelial cell migration [GO:0043534]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; endothelial cell development [GO:0001885]; fat cell differentiation [GO:0045444]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide catabolic process [GO:0042744]; interaction with symbiont [GO:0051702]; lipoxygenase pathway [GO:0019372]; myoblast proliferation [GO:0051450]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of supramolecular fiber organization [GO:1902905]; protein oxidation [GO:0018158]; purine nucleotide catabolic process [GO:0006195]; regulation of gene expression, epigenetic [GO:0040029]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of proteasomal protein catabolic process [GO:0061136]; response to gamma radiation [GO:0010332]; response to hydrogen peroxide [GO:0042542]; response to hydroperoxide [GO:0033194]; response to selenium ion [GO:0010269]; response to symbiotic bacterium [GO:0009609]; response to xenobiotic stimulus [GO:0009410]; sensory perception of sound [GO:0007605]; skeletal muscle fiber development [GO:0048741]; skeletal muscle tissue regeneration [GO:0043403]; temperature homeostasis [GO:0001659]; triglyceride metabolic process [GO:0006641]; UV protection [GO:0009650]; vasodilation [GO:0042311]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; SH3 domain binding [GO:0017124]
d3hzaa1_d4a6ad___1			Actinobacteria	Actinobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d3hzbb__d2dada1__1		Metazoa	Bacteroidetes	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d3hzbc__d1zgta1__1		Metazoa	Bacteroidetes	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3hzbe__d2bv2a___1			Bacteroidetes		carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]						carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	
d3hzbe__d2kfba1__1		Metazoa	Bacteroidetes	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]		cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3hzbf__d2k1xa1__1			Bacteroidetes	Euryarchaeota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3hzbg__d1zwoa1__1		Metazoa	Bacteroidetes	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3hzbg__d3hz2a___1			Bacteroidetes	Euryarchaeota	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3hzbh__d1a7hb___1		Metazoa	Bacteroidetes	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; morphogenesis of an epithelium [GO:0002009]; visual perception [GO:0007601]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3hzdb__d1poda___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]; antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]
d3hzka1_d1ypzg1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3hzka2_d1u8oa2__1												
d3hzma1_d1qvod1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3hzma1_d4u0qb2__1				Apicomplexa								
d3hzra__d1mrzb2__1				Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]; FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	tryptophanyl-tRNA aminoacylation [GO:0006436]	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; FMN adenylyltransferase activity [GO:0003919]; riboflavin kinase activity [GO:0008531]
d3hzrc__d5o0bb___1				Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	tryptophanyl-tRNA aminoacylation [GO:0006436]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d3hzva1_d3bkcl2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3hzva2_d1yy9c2__1		Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d3hzya1_d2gj6d1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3i02a1_d1h0da1__1		Metazoa		Chordata		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]		actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]
d3i02c1_d3to4c1__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3i03a__d3u8ba___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]; antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]
d3i0ha__d2vs3a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d3i0sa2_d2g8fa1__1				Firmicutes	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d3i12c1_d2w71c1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d3i12d1_d1keee3__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d3i17b__d1ifba___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d3i17b__d1mfhd___1	Metazoa		Chordata		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]	
d3i1ca__d2dsod___1	Metazoa		Mollusca	Firmicutes	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]				cytoplasm [GO:0005737]	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3i1fa1_d1qzwc3__1			Crenarchaeota	Crenarchaeota	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytosol [GO:0005829]	signal recognition particle [GO:0048500]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d3i1fa2_d3b8hc2__1			Crenarchaeota	Proteobacteria	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d3i1fa3_d1d8tb2__1			Crenarchaeota	Actinobacteria	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	extracellular region [GO:0005576]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytosol [GO:0005829]	extracellular region [GO:0005576]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	
d3i1fa3_d4lbza3__1			Crenarchaeota	Deinococcus-Thermus	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3i1fb2_d3b8ha2__1			Crenarchaeota	Proteobacteria	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d3i1va2_d5aewv___1				Proteobacteria		biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]				biphenyl 2,3-dioxygenase activity [GO:0018687]
d3i1xb2_d2f86b1__1		Metazoa		Nematoda (roundworms)		axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]		MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]		axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]		ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d3i1xb2_d4nhfe___1				Proteobacteria		integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; protein secretion by the type IV secretion system [GO:0030255]		protein secretion by the type IV secretion system [GO:0030255]		integral component of membrane [GO:0016021]		metal ion binding [GO:0046872]
d3i1ya1_d2b82a___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	outer membrane-bounded periplasmic space [GO:0030288]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	acid phosphatase activity [GO:0003993]; cofactor binding [GO:0048037]; metal ion binding [GO:0046872]; phosphoserine phosphatase activity [GO:0004647]
d3i1ya2_d4dnpa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	
d3i29b__d3n7kb2__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; ganglioside binding [GO:0035594]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; membrane protein proteolysis [GO:0033619]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of neurotransmitter secretion [GO:0046929]	digestion [GO:0007586]; proteolysis [GO:0006508]	membrane protein proteolysis [GO:0033619]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ganglioside binding [GO:0035594]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d3i2bb__d2yzce1__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	urate oxidase activity [GO:0004846]
d3i2bc__d2ibaa2__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	peroxisome [GO:0005777]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	urate oxidase activity [GO:0004846]
d3i2bd__d3qn9a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	queuosine biosynthetic process [GO:0008616]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d3i2bd__d4fska1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	peroxisome [GO:0005777]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	urate oxidase activity [GO:0004846]
d3i2bf__d2o9mc___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	
d3i2bf__d2yzed1__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	urate oxidase activity [GO:0004846]
d3i2bi__d4cw6a1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	peroxisome [GO:0005777]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	urate oxidase activity [GO:0004846]
d3i2bj__d1wuqb___1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d3i2bj__d3qnac___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	queuosine biosynthetic process [GO:0008616]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d3i2bk__d1wm9e___1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d3i2bk__d4r99d1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	
d3i2bl__d1n3tn___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d3i2bl__d4ntke___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	queuosine biosynthetic process [GO:0008616]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d3i2cl1_d3bgfc1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3i2fa2_d2vnra___1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cocaine catabolic process [GO:0050784]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]	metal ion binding [GO:0046872]
d3i2ga1_d2b4ka2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	cocaine catabolic process [GO:0050784]		cytoplasm [GO:0005737]		carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d3i2ha2_d3iapb1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cocaine catabolic process [GO:0050784]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]	beta-galactosidase complex [GO:0009341]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i2ia1_d1r88b___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	extracellular region [GO:0005576]; fibronectin binding [GO:0001968]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; zymogen binding [GO:0035375]; mycolate cell wall layer assembly [GO:0071769]	cocaine catabolic process [GO:0050784]	mycolate cell wall layer assembly [GO:0071769]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]	fibronectin binding [GO:0001968]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; zymogen binding [GO:0035375]
d3i2ia2_d3iaqc1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cocaine catabolic process [GO:0050784]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]	beta-galactosidase complex [GO:0009341]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i2ia2_d4duvd1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cocaine catabolic process [GO:0050784]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]	beta-galactosidase complex [GO:0009341]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i2ja1_d1h2wa2__1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cocaine catabolic process [GO:0050784]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d3i2ja1_d1nx9c2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	cocaine catabolic process [GO:0050784]		cytoplasm [GO:0005737]		carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d3i2ka2_d1f49g3__1			Actinobacteria		cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]		cocaine catabolic process [GO:0050784]		cytoplasm [GO:0005737]		carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]	
d3i2ka2_d4duwc1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cocaine catabolic process [GO:0050784]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]	beta-galactosidase complex [GO:0009341]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i2oa__d2xmlb___1		Metazoa	Proteobacteria	Chordata	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	histone methyltransferase complex [GO:0035097]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; androgen receptor binding [GO:0050681]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; zinc ion binding [GO:0008270]; blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827]		histone methyltransferase complex [GO:0035097]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]	androgen receptor binding [GO:0050681]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; zinc ion binding [GO:0008270]
d3i2xb1_d4tlpa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	serine-type endopeptidase inhibitor activity [GO:0004867]	serine-type endopeptidase inhibitor activity [GO:0004867]					serine-type endopeptidase inhibitor activity [GO:0004867]	serine-type endopeptidase inhibitor activity [GO:0004867]
d3i33a1_d4czmb1__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; CatSper complex [GO:0036128]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; meiotic spindle [GO:0072687]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptonemal complex [GO:0000795]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; glycolipid binding [GO:0051861]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; tau protein binding [GO:0048156]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein phosphorylation [GO:0001934]; protein refolding [GO:0042026]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex disassembly [GO:0070194]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein phosphorylation [GO:0001934]; protein refolding [GO:0042026]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex disassembly [GO:0070194]; vesicle-mediated transport [GO:0016192]	cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	blood microparticle [GO:0072562]; CatSper complex [GO:0036128]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; meiotic spindle [GO:0072687]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptonemal complex [GO:0000795]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; glycolipid binding [GO:0051861]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; tau protein binding [GO:0048156]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]
d3i33a2_d3l4ia2__1	Metazoa		Chordata	Apicomplexa	blood microparticle [GO:0072562]; CatSper complex [GO:0036128]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; meiotic spindle [GO:0072687]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptonemal complex [GO:0000795]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; glycolipid binding [GO:0051861]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; tau protein binding [GO:0048156]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein phosphorylation [GO:0001934]; protein refolding [GO:0042026]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex disassembly [GO:0070194]; vesicle-mediated transport [GO:0016192]	ATP binding [GO:0005524]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein phosphorylation [GO:0001934]; protein refolding [GO:0042026]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex disassembly [GO:0070194]; vesicle-mediated transport [GO:0016192]		blood microparticle [GO:0072562]; CatSper complex [GO:0036128]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; male germ cell nucleus [GO:0001673]; meiotic spindle [GO:0072687]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synaptonemal complex [GO:0000795]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; glycolipid binding [GO:0051861]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; tau protein binding [GO:0048156]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]
d3i3ac__d1ocxb___1			Spirochaetes	Proteobacteria	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; maltose O-acetyltransferase activity [GO:0008925]; protein homotrimerization [GO:0070207]	lipid A biosynthetic process [GO:0009245]	protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]	identical protein binding [GO:0042802]; maltose O-acetyltransferase activity [GO:0008925]
d3i3ba3_d1jz8a5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i3ba4_d1f49a1__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3i3bb3_d5do8a1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	alpha-amylase activity [GO:0004556]; oligosaccharide catabolic process [GO:0009313]	lactose catabolic process [GO:0005990]	oligosaccharide catabolic process [GO:0009313]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-amylase activity [GO:0004556]
d3i3bb4_d2vzvb2__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3i3bb5_d1mn0b1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d3i3bc2_d3t0dd4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i3bd2_d3czja4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i3bd3_d3iaqb3__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i3bd4_d3t0aa2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i3da3_d1px4a5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i3da3_d4f79a1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	6-phospho-beta-glucosidase activity [GO:0008706]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	6-phospho-beta-glucosidase activity [GO:0008706]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]
d3i3da5_d3sepb5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i3dc2_d5c71c2__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3i3dc4_d3dymb2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i3dc5_d3t2pa5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i3dd1_d2vmfa4__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-mannosidase activity [GO:0004567]
d3i3ea4_d2vr4a1__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-mannosidase activity [GO:0004567]
d3i3ec2_d2wbkb5__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-mannosidase activity [GO:0004567]
d3i3ec3_d1b9za2__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3i3ec4_d3vdcd2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i3ed2_d2vzvb4__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3i3ed2_d3vd3b4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3i3ed3_d3pzoa___1			Proteobacteria	Thermotogae	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]
d3i3ed4_d3lpfb2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	lactose catabolic process [GO:0005990]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	beta-galactosidase complex [GO:0009341]	cytosol [GO:0005829]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d3i3ga__d1mj9a___1		Fungi		Ascomycota	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; glycosome [GO:0020015]; Golgi apparatus [GO:0005794]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]; N-acetylglucosamine metabolic process [GO:0006044]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	histone acetyltransferase complex [GO:0000123]; NuA4 histone acetyltransferase complex [GO:0035267]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; Piccolo NuA4 histone acetyltransferase complex [GO:0032777]; H4 histone acetyltransferase activity [GO:0010485]; histone acetyltransferase activity [GO:0004402]; histone binding [GO:0042393]; peptide N-acetyltransferase activity [GO:0034212]; chromatin silencing at rDNA [GO:0000183]; DNA repair [GO:0006281]; DNA-templated transcription, elongation [GO:0006354]; histone acetylation [GO:0016573]; histone displacement [GO:0001207]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of macroautophagy [GO:0016239]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]	N-acetylglucosamine metabolic process [GO:0006044]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	chromatin silencing at rDNA [GO:0000183]; DNA repair [GO:0006281]; DNA-templated transcription, elongation [GO:0006354]; histone acetylation [GO:0016573]; histone displacement [GO:0001207]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of macroautophagy [GO:0016239]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; glycosome [GO:0020015]; Golgi apparatus [GO:0005794]	histone acetyltransferase complex [GO:0000123]; NuA4 histone acetyltransferase complex [GO:0035267]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; Piccolo NuA4 histone acetyltransferase complex [GO:0032777]	glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]	H4 histone acetyltransferase activity [GO:0010485]; histone acetyltransferase activity [GO:0004402]; histone binding [GO:0042393]; peptide N-acetyltransferase activity [GO:0034212]
d3i3jd__d5ek9b___1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]; acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]
d3i3je__d4nr4b___1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]; acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3i3je__d5a5pa1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]; acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; chromatin organization [GO:0006325]; negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]	animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	chromatin organization [GO:0006325]; negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; histone binding [GO:0042393]
d3i3jl__d5ea1c___1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]; acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	extracellular space [GO:0005615]; membrane [GO:0016020]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SWI/SNF complex [GO:0016514]; androgen receptor binding [GO:0050681]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA polymerase binding [GO:0070182]; DNA-dependent ATPase activity [GO:0008094]; helicase activity [GO:0004386]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]; Tat protein binding [GO:0030957]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; ATP-dependent chromatin remodeling [GO:0043044]; beta-catenin-TCF complex assembly [GO:1904837]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of cell growth [GO:0030308]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; neural retina development [GO:0003407]; nucleosome disassembly [GO:0006337]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of glucose mediated signaling pathway [GO:1902661]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription by RNA polymerase II [GO:0006357]	animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	ATP-dependent chromatin remodeling [GO:0043044]; beta-catenin-TCF complex assembly [GO:1904837]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of cell growth [GO:0030308]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; neural retina development [GO:0003407]; nucleosome disassembly [GO:0006337]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of glucose mediated signaling pathway [GO:1902661]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription by RNA polymerase II [GO:0006357]	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]	extracellular space [GO:0005615]; membrane [GO:0016020]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; SWI/SNF complex [GO:0016514]	acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]	androgen receptor binding [GO:0050681]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA polymerase binding [GO:0070182]; helicase activity [GO:0004386]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase I CORE element sequence-specific DNA binding [GO:0001164]; Tat protein binding [GO:0030957]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]
d3i3oc__d3rihb___1			Firmicutes	Actinobacteria	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]						metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	
d3i3qa__d5pica___1		Metazoa	Proteobacteria	Chordata	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]		blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d3i3tb__d5chwe1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3i3xb__d4hzdb___1			Spirochaetes	Proteobacteria	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	cytoplasm [GO:0005737]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]	lipid A biosynthetic process [GO:0009245]	cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]	serine O-acetyltransferase activity [GO:0009001]
d3i43a__d1fohb3__1		Fungi	Proteobacteria	Basidiomycota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]; phenol-containing compound catabolic process [GO:0019336]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	phenol-containing compound catabolic process [GO:0019336]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]		hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]
d3i43b__d4xtso___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	cell [GO:0005623]; cytosol [GO:0005829]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]	thioredoxin peroxidase activity [GO:0008379]
d3i46a__d5cfga___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]		aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	extracellular region [GO:0005576]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]
d3i46b__d3g00b___1			Firmicutes	Euryarchaeota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]		DNA repair [GO:0006281]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; phosphoric diester hydrolase activity [GO:0008081]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d3i49a__d3o1sa___1			Proteobacteria	Proteobacteria	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]			1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]
d3i4ia__d1z3ta___1		Fungi		Basidiomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3i4ob__d1lylb1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation initiation factor activity [GO:0003743]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]		lysyl-tRNA aminoacylation [GO:0006430]; tRNA aminoacylation for protein translation [GO:0006418]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; membrane [GO:0016020]	ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation initiation factor activity [GO:0003743]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]
d3i50l1_d2otpb1__1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; antigen binding [GO:0003823]; IgM binding [GO:0001791]; signaling receptor activity [GO:0038023]; defense response [GO:0006952]; granulocyte colony-stimulating factor production [GO:0071611]; granulocyte macrophage colony-stimulating factor production [GO:0032604]; innate immune response [GO:0045087]; innate immune response activating cell surface receptor signaling pathway [GO:0002220]; interleukin-6 production [GO:0032635]; interleukin-8 production [GO:0032637]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; neutrophil activation involved in immune response [GO:0002283]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell activation [GO:0050867]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of tumor necrosis factor secretion [GO:1904469]; signal transduction [GO:0007165]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	defense response [GO:0006952]; granulocyte colony-stimulating factor production [GO:0071611]; granulocyte macrophage colony-stimulating factor production [GO:0032604]; innate immune response [GO:0045087]; innate immune response activating cell surface receptor signaling pathway [GO:0002220]; interleukin-6 production [GO:0032635]; interleukin-8 production [GO:0032637]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; neutrophil activation involved in immune response [GO:0002283]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell activation [GO:0050867]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of tumor necrosis factor secretion [GO:1904469]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; IgM binding [GO:0001791]; signaling receptor activity [GO:0038023]
d3i50l2_d4kv5k1__1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; antigen binding [GO:0003823]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; type II transforming growth factor beta receptor binding [GO:0005114]; type III transforming growth factor beta receptor binding [GO:0034714]; aortic valve morphogenesis [GO:0003180]; ATP biosynthetic process [GO:0006754]; BMP signaling pathway [GO:0030509]; cell cycle arrest [GO:0007050]; cell development [GO:0048468]; cell migration [GO:0016477]; cell-cell junction organization [GO:0045216]; cellular response to organic cyclic compound [GO:0071407]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chondrocyte differentiation [GO:0002062]; common-partner SMAD protein phosphorylation [GO:0007182]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; embryonic liver development [GO:1990402]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial to mesenchymal transition [GO:0001837]; evasion or tolerance of host defenses by virus [GO:0019049]; extracellular matrix assembly [GO:0085029]; extrinsic apoptotic signaling pathway [GO:0097191]; heart development [GO:0007507]; heart valve morphogenesis [GO:0003179]; hematopoietic progenitor cell differentiation [GO:0002244]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymph node development [GO:0048535]; macrophage derived foam cell differentiation [GO:0010742]; MAPK cascade [GO:0000165]; membrane protein intracellular domain proteolysis [GO:0031293]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cytolysis [GO:0045918]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of skeletal muscle tissue development [GO:0048642]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; ossification involved in bone remodeling [GO:0043932]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; phosphate-containing compound metabolic process [GO:0006796]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of chemotaxis [GO:0050921]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglia differentiation [GO:0014008]; positive regulation of NAD+ ADP-ribosyltransferase activity [GO:1901666]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular permeability [GO:0043117]; protein export from nucleus [GO:0006611]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor catabolic process [GO:0032801]; regulation of apoptotic process [GO:0042981]; regulation of binding [GO:0051098]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of DNA binding [GO:0051101]; regulation of MAPK cascade [GO:0043408]; regulation of protein import into nucleus [GO:0042306]; regulation of SMAD protein signal transduction [GO:0060390]; regulation of striated muscle tissue development [GO:0016202]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; salivary gland morphogenesis [GO:0007435]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transforming growth factor beta receptor signaling pathway involved in heart development [GO:1905313]; vasculogenesis [GO:0001570]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	aortic valve morphogenesis [GO:0003180]; ATP biosynthetic process [GO:0006754]; BMP signaling pathway [GO:0030509]; cell-cell junction organization [GO:0045216]; cell cycle arrest [GO:0007050]; cell development [GO:0048468]; cell migration [GO:0016477]; cellular response to organic cyclic compound [GO:0071407]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chondrocyte differentiation [GO:0002062]; common-partner SMAD protein phosphorylation [GO:0007182]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; embryonic liver development [GO:1990402]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial to mesenchymal transition [GO:0001837]; evasion or tolerance of host defenses by virus [GO:0019049]; extracellular matrix assembly [GO:0085029]; extrinsic apoptotic signaling pathway [GO:0097191]; heart development [GO:0007507]; heart valve morphogenesis [GO:0003179]; hematopoietic progenitor cell differentiation [GO:0002244]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymph node development [GO:0048535]; macrophage derived foam cell differentiation [GO:0010742]; MAPK cascade [GO:0000165]; membrane protein intracellular domain proteolysis [GO:0031293]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytolysis [GO:0045918]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of skeletal muscle tissue development [GO:0048642]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; ossification involved in bone remodeling [GO:0043932]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; phosphate-containing compound metabolic process [GO:0006796]; platelet degranulation [GO:0002576]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of chemotaxis [GO:0050921]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglia differentiation [GO:0014008]; positive regulation of NAD+ ADP-ribosyltransferase activity [GO:1901666]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein secretion [GO:0050714]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular permeability [GO:0043117]; protein export from nucleus [GO:0006611]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor catabolic process [GO:0032801]; regulation of apoptotic process [GO:0042981]; regulation of binding [GO:0051098]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; regulation of DNA binding [GO:0051101]; regulation of MAPK cascade [GO:0043408]; regulation of protein import into nucleus [GO:0042306]; regulation of SMAD protein signal transduction [GO:0060390]; regulation of striated muscle tissue development [GO:0016202]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; salivary gland morphogenesis [GO:0007435]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transforming growth factor beta receptor signaling pathway involved in heart development [GO:1905313]; vasculogenesis [GO:0001570]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; growth factor activity [GO:0008083]; identical protein binding [GO:0042802]; transforming growth factor beta receptor binding [GO:0005160]; type III transforming growth factor beta receptor binding [GO:0034714]; type II transforming growth factor beta receptor binding [GO:0005114]; type I transforming growth factor beta receptor binding [GO:0034713]
d3i54c1_d4i01a1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3i54d2_d3fweb2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3i59a2_d4i02c2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3i5fb__d4clna___1	Metazoa	Metazoa	Mollusca	Arthropoda	myosin complex [GO:0016459]; calcium ion binding [GO:0005509]	cell [GO:0005623]; cell cortex [GO:0005938]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; myosin V complex [GO:0031475]; myosin VI complex [GO:0031476]; nucleoplasm [GO:0005654]; rhabdomere [GO:0016028]; spindle [GO:0005819]; calcium ion binding [GO:0005509]; myosin heavy chain binding [GO:0032036]; myosin V binding [GO:0031489]; myosin VI head/neck binding [GO:0070855]; actin filament-based movement [GO:0030048]; adaptation of rhodopsin mediated signaling [GO:0016062]; calcium-mediated signaling [GO:0019722]; cellular response to ethanol [GO:0071361]; centriole replication [GO:0007099]; deactivation of rhodopsin mediated signaling [GO:0016059]; kinetochore organization [GO:0051383]; metarhodopsin inactivation [GO:0016060]; muscle cell cellular homeostasis [GO:0046716]; photoreceptor cell axon guidance [GO:0072499]; positive regulation of cation channel activity [GO:2001259]; protein phosphorylation [GO:0006468]; regulation of light-activated channel activity [GO:0016061]; rhabdomere development [GO:0042052]; rhodopsin mediated signaling pathway [GO:0016056]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]		actin filament-based movement [GO:0030048]; adaptation of rhodopsin mediated signaling [GO:0016062]; calcium-mediated signaling [GO:0019722]; cellular response to ethanol [GO:0071361]; centriole replication [GO:0007099]; deactivation of rhodopsin mediated signaling [GO:0016059]; kinetochore organization [GO:0051383]; metarhodopsin inactivation [GO:0016060]; muscle cell cellular homeostasis [GO:0046716]; photoreceptor cell axon guidance [GO:0072499]; positive regulation of cation channel activity [GO:2001259]; protein phosphorylation [GO:0006468]; regulation of light-activated channel activity [GO:0016061]; rhabdomere development [GO:0042052]; rhodopsin mediated signaling pathway [GO:0016056]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]	myosin complex [GO:0016459]	cell [GO:0005623]; cell cortex [GO:0005938]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; myosin V complex [GO:0031475]; myosin VI complex [GO:0031476]; nucleoplasm [GO:0005654]; rhabdomere [GO:0016028]; spindle [GO:0005819]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; myosin heavy chain binding [GO:0032036]; myosin V binding [GO:0031489]; myosin VI head/neck binding [GO:0070855]
d3i5gb__d4upua___1	Metazoa	Metazoa	Mollusca	Chordata	myosin complex [GO:0016459]; calcium ion binding [GO:0005509]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	myosin complex [GO:0016459]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d3i5ja__d1otkb1__1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	toluene catabolic process [GO:0042203]	phenylacetate catabolic process [GO:0010124]		cytosol [GO:0005829]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	
d3i5je__d1g10a___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	monooxygenase activity [GO:0004497]; toluene catabolic process [GO:0042203]	toluene catabolic process [GO:0042203]	toluene catabolic process [GO:0042203]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	monooxygenase activity [GO:0004497]
d3i5va__d3g0rb___1			Firmicutes	Euryarchaeota	extracellular region [GO:0005576]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; hemolysis in other organism [GO:0044179]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	hemolysis in other organism [GO:0044179]	DNA repair [GO:0006281]	extracellular region [GO:0005576]		phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d3i5vb__d1de8a___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; hemolysis in other organism [GO:0044179]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	hemolysis in other organism [GO:0044179]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	extracellular region [GO:0005576]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]
d3i5vd__d3u8ub___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]; hemolysis in other organism [GO:0044179]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	hemolysis in other organism [GO:0044179]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	extracellular region [GO:0005576]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	phosphatidylcholine phospholipase C activity [GO:0034480]; toxin activity [GO:0090729]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]
d3i68a__d4ls1a___1		Metazoa	Apicomplexa	Chordata	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; dihydroorotate dehydrogenase activity [GO:0004152]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; response to drug [GO:0042493]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; response to drug [GO:0042493]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]	dihydroorotate dehydrogenase activity [GO:0004152]	dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]
d3i69b1_d1yexc___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytosol [GO:0005829]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	thioredoxin peroxidase activity [GO:0008379]
d3i69b1_d3hjma1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3i69b2_d2r5ga2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; intracellular [GO:0005622]; nucleus [GO:0005634]; chloride channel activity [GO:0005254]; glutathione peroxidase activity [GO:0004602]; voltage-gated ion channel activity [GO:0005244]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of binding [GO:0051099]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of binding [GO:0051099]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; intracellular [GO:0005622]; nucleus [GO:0005634]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	chloride channel activity [GO:0005254]; glutathione peroxidase activity [GO:0004602]; voltage-gated ion channel activity [GO:0005244]
d3i69c1_d1guka2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cellular response to lithium ion [GO:0071285]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to nicotine [GO:0035094]; response to zinc ion [GO:0010043]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d3i69c1_d3o6tb___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; S-nitrosoglutathione reductase activity [GO:0080007]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; S-nitrosoglutathione reductase activity [GO:0080007]
d3i69e1_d2wcib___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytosol [GO:0005829]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]
d3i69g1_d4xcsc1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; RNA binding [GO:0003723]; thioredoxin peroxidase activity [GO:0008379]; cell population proliferation [GO:0008283]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; erythrocyte homeostasis [GO:0034101]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of stress-activated MAPK cascade [GO:0032872]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]; retina homeostasis [GO:0001895]; skeletal system development [GO:0001501]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell population proliferation [GO:0008283]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; erythrocyte homeostasis [GO:0034101]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of stress-activated MAPK cascade [GO:0032872]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]; retina homeostasis [GO:0001895]; skeletal system development [GO:0001501]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; RNA binding [GO:0003723]; thioredoxin peroxidase activity [GO:0008379]
d3i69g2_d2wrtg2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d3i69h2_d5ecrc2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d3i6aa1_d2yana1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; [2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	[2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]
d3i6ab1_d2l5oa1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	oxidoreductase activity [GO:0016491]
d3i6ab2_d4kdya2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; isomerase activity [GO:0016853]; aromatic amino acid family metabolic process [GO:0009072]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	aromatic amino acid family metabolic process [GO:0009072]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	isomerase activity [GO:0016853]
d3i6ac1_d1de2a___1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d3i6ae1_d2oe1b___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; mitochondrion [GO:0005739]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; mitochondrion [GO:0005739]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]
d3i6af1_d3zl5i___1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d3i6af2_d2wb9b2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d3i6ba__d3i76b___1			Proteobacteria	Firmicutes	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	hydrolase activity [GO:0016787]	lipopolysaccharide biosynthetic process [GO:0009103]				3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	hydrolase activity [GO:0016787]
d3i6bb__d2gmwa1__1			Proteobacteria	Proteobacteria	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]; D,D-heptose 1,7-bisphosphate phosphatase activity [GO:0034200]; magnesium ion binding [GO:0000287]; zinc ion binding [GO:0008270]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	lipopolysaccharide biosynthetic process [GO:0009103]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]		cytosol [GO:0005829]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	D,D-heptose 1,7-bisphosphate phosphatase activity [GO:0034200]; magnesium ion binding [GO:0000287]; zinc ion binding [GO:0008270]
d3i6eb2_d2ggec1__1			Proteobacteria	Firmicutes	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]				chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3i6eg2_d3sbfa2__1			Proteobacteria	Proteobacteria	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]	cellular amino acid catabolic process [GO:0009063]			chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]	magnesium ion binding [GO:0000287]
d3i6ge1_d3kykl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3i6ma__d4lkob2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	acetylcholinesterase activity [GO:0003990]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3i6ob__d3r4ba___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3i6pa__d4qiff___1			Proteobacteria	Proteobacteria	ethanolamine degradation polyhedral organelle [GO:0031471]; structural molecule activity [GO:0005198]; ethanolamine catabolic process [GO:0046336]		ethanolamine catabolic process [GO:0046336]		ethanolamine degradation polyhedral organelle [GO:0031471]		structural molecule activity [GO:0005198]	
d3i6pe__d4qief___1			Proteobacteria	Proteobacteria	ethanolamine degradation polyhedral organelle [GO:0031471]; structural molecule activity [GO:0005198]; ethanolamine catabolic process [GO:0046336]		ethanolamine catabolic process [GO:0046336]		ethanolamine degradation polyhedral organelle [GO:0031471]		structural molecule activity [GO:0005198]	
d3i6ra__d4rkaa___1		Metazoa	Apicomplexa	Chordata	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; dihydroorotate dehydrogenase activity [GO:0004152]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; response to drug [GO:0042493]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; response to drug [GO:0042493]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]	dihydroorotate dehydrogenase activity [GO:0004152]	dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]
d3i75a1_d1c16b___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3i75a1_d2iamd1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3i75a2_d2gj7a1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3i75a2_d4xvsl1__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d3i78a__d1p06a___1			Actinobacteria	Proteobacteria	serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]				extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d3i7ea__d5p75a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3i7eb__d3i6oa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3i8ta__d2eigc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]			collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]		carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3i8ux__d2g18b1__1			Cyanobacteria	Cyanobacteria	cobalt ion binding [GO:0050897]; phycocyanobilin:ferredoxin oxidoreductase activity [GO:0050620]; phytochromobilin biosynthetic process [GO:0010024]	cobalt ion binding [GO:0050897]; phycocyanobilin:ferredoxin oxidoreductase activity [GO:0050620]; phytochromobilin biosynthetic process [GO:0010024]	phytochromobilin biosynthetic process [GO:0010024]	phytochromobilin biosynthetic process [GO:0010024]			cobalt ion binding [GO:0050897]; phycocyanobilin:ferredoxin oxidoreductase activity [GO:0050620]	cobalt ion binding [GO:0050897]; phycocyanobilin:ferredoxin oxidoreductase activity [GO:0050620]
d3i8wa__d3kfrb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3i8wa__d5ozca___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3i94a__d3f0ka___1			Cyanobacteria		cobalt ion binding [GO:0050897]; phycocyanobilin:ferredoxin oxidoreductase activity [GO:0050620]; phytochromobilin biosynthetic process [GO:0010024]		phytochromobilin biosynthetic process [GO:0010024]				cobalt ion binding [GO:0050897]; phycocyanobilin:ferredoxin oxidoreductase activity [GO:0050620]	
d3i98c__d3fq3j___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3i98f__d4z70b1__1			Euryarchaeota	Actinobacteria	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3i9ab__d3iwvc___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d3i9gl1_d1fg2g1__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3i9gl1_d4zncf2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3i9ha__d2bv2b___1			Firmicutes		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d3i9hd__d1blbc2__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			metal ion binding [GO:0046872]	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]
d3i9hg__d2g98a2__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]		cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3i9hh__d4gcra1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3i9ja__d1f8ya___1	Metazoa		Mollusca	Firmicutes	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	nucleoside deoxyribosyltransferase activity [GO:0050144]; nucleotide salvage [GO:0043173]	single fertilization [GO:0007338]	nucleotide salvage [GO:0043173]	cytoplasmic vesicle [GO:0031410]		NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	nucleoside deoxyribosyltransferase activity [GO:0050144]
d3i9lb__d3zwmd1__1	Metazoa	Metazoa	Mollusca	Mollusca	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	single fertilization [GO:0007338]	single fertilization [GO:0007338]	cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]
d3i9mb__d4mejb___1	Metazoa		Chordata	Firmicutes	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	transferase activity [GO:0016740]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]		basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]		identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	transferase activity [GO:0016740]
d3i9na__d3gh3a___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	plasma membrane [GO:0005886]; NAD glycohydrolase activity [GO:0061810]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]; metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD glycohydrolase activity [GO:0061810]; phosphorus-oxygen lyase activity [GO:0016849]
d3i9pb__d4y9ba___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3i9ta__d1otwa1__1	Metazoa		Chordata	Proteobacteria	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]; angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	pyrroloquinoline-quinone synthase activity [GO:0033732]; pyrroloquinoline quinone biosynthetic process [GO:0018189]	angiogenesis [GO:0001525]; cell death [GO:0008219]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; phospholipid metabolic process [GO:0006644]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; wound healing involved in inflammatory response [GO:0002246]	pyrroloquinoline quinone biosynthetic process [GO:0018189]	caveola [GO:0005901]; cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]		enzyme binding [GO:0019899]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; phospholipase D activity [GO:0004630]; protein homodimerization activity [GO:0042803]	pyrroloquinoline-quinone synthase activity [GO:0033732]
d3i9v7__d1soya___1			Deinococcus-Thermus	Proteobacteria	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; iron-sulfur cluster assembly [GO:0016226]		iron-sulfur cluster assembly [GO:0016226]	plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	quinone binding [GO:0048038]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]
d3i9vc3_d1ogyi2__1			Deinococcus-Thermus	Proteobacteria	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]		anaerobic respiration [GO:0009061]	plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	quinone binding [GO:0048038]	metal ion binding [GO:0046872]
d3ia2b__d1hkha___1			Proteobacteria	Actinobacteria	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	peroxidase activity [GO:0004601]					arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	peroxidase activity [GO:0004601]
d3ia4a__d3qlxa1__1		Fungi	Proteobacteria	Ascomycota	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d3ia4b__d3ix9b___1			Proteobacteria	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3iaja__d1h4ax1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]		cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3iamc1_d2w3ra1__1			Deinococcus-Thermus	Proteobacteria	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]			plasma membrane [GO:0005886]		quinone binding [GO:0048038]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3iamc4_d1vldq1__1			Deinococcus-Thermus		plasma membrane [GO:0005886]; quinone binding [GO:0048038]				plasma membrane [GO:0005886]		quinone binding [GO:0048038]	
d3iamg__d1ti2h2__1			Deinococcus-Thermus		plasma membrane [GO:0005886]; quinone binding [GO:0048038]				plasma membrane [GO:0005886]		quinone binding [GO:0048038]	
d3iamh__d3t3td___1		Metazoa	Deinococcus-Thermus	Chordata	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]		adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	quinone binding [GO:0048038]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]
d3iapb3_d4nxsb1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	lactose catabolic process [GO:0005990]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	beta-galactosidase complex [GO:0009341]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d3iapb5_d1nsvb1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d3iapc1_d1shwb___1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	lactose catabolic process [GO:0005990]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]	beta-galactosidase complex [GO:0009341]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3iapc2_d3k4ab2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	lactose catabolic process [GO:0005990]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	beta-galactosidase complex [GO:0009341]	cytosol [GO:0005829]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d3iapc3_d2gk1.b__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	lactose catabolic process [GO:0005990]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	beta-galactosidase complex [GO:0009341]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d3iapc5_d3dx1a3__1		Metazoa	Proteobacteria	Arthropoda	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d3iapd1_d2b9va1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d3iapd3_d1qhpa4__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	glucan 1,4-alpha-maltohydrolase activity [GO:0043897]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3iapd4_d3t2oa2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3iapd5_d1r34a2__1		Metazoa	Proteobacteria	Arthropoda	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d3iaqa3_d1bglg5__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3iaqa3_d3t2oc3__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3iaqa5_d2brvx3__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	cell wall [GO:0005618]; extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d3iaqb3_d4w89a___1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]
d3iaqc2_d1jyvd2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3iaqd3_d3w27a___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d3iaqd4_d2vztb2__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3ias2__d4yqvb1__1		Metazoa	Deinococcus-Thermus	Chordata	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]		cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	quinone binding [GO:0048038]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d3iash__d3t3ta___1		Metazoa	Deinococcus-Thermus	Chordata	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]		adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	quinone binding [GO:0048038]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]
d3iass1_d2fugj2__1			Deinococcus-Thermus	Deinococcus-Thermus	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]			plasma membrane [GO:0005886]	plasma membrane [GO:0005886]	quinone binding [GO:0048038]	quinone binding [GO:0048038]
d3iasu4_d3ir5a2__1			Deinococcus-Thermus	Proteobacteria	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]	plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]	quinone binding [GO:0048038]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]
d3ib9b1_d4q1ib___1			Actinobacteria	Firmicutes	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; antibiotic biosynthetic process [GO:0017000]; fatty acid beta-oxidation [GO:0006635]	fatty acid biosynthetic process [GO:0006633]	antibiotic biosynthetic process [GO:0017000]; fatty acid beta-oxidation [GO:0006635]	acetyl-CoA carboxylase complex [GO:0009317]	cytoplasm [GO:0005737]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]
d3ibda1_d4cp4a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; cellular ketone metabolic process [GO:0042180]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cellular ketone metabolic process [GO:0042180]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3ibda1_d4uhlh1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; cellular ketone metabolic process [GO:0042180]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]; cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cellular ketone metabolic process [GO:0042180]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	arachidonic acid epoxygenase activity [GO:0008392]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]
d3iboa__d3t71a2__1		Fungi	Proteobacteria	Basidiomycota	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3ibob__d1fwxd1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	membrane [GO:0016020]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d3ic0a__d1ngkc___1	Metazoa		Chordata	Actinobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d3ic0b__d3d1kb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3icba__d4xjka___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; antimicrobial humoral response [GO:0019730]; apoptotic process [GO:0006915]; astrocyte development [GO:0014002]; autocrine signaling [GO:0035425]; autophagy [GO:0006914]; chemokine production [GO:0032602]; chronic inflammatory response [GO:0002544]; cytokine production [GO:0001816]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; neutrophil aggregation [GO:0070488]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of cell growth [GO:0030307]; positive regulation of inflammatory response [GO:0050729]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptide secretion [GO:0002793]; regulation of cytoskeleton organization [GO:0051493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; toll-like receptor signaling pathway [GO:0002224]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intermediate filament cytoskeleton [GO:0045111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium ion binding [GO:0005509]; vitamin D binding [GO:0005499]	arachidonic acid binding [GO:0050544]; calcium ion binding [GO:0005509]; microtubule binding [GO:0008017]; RAGE receptor binding [GO:0050786]; Toll-like receptor 4 binding [GO:0035662]; zinc ion binding [GO:0008270]
d3icha__d1x7fa1__1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; unfolded protein binding [GO:0051082]; bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by host of viral process [GO:0044794]; positive regulation of multicellular organism growth [GO:0040018]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]	catalytic activity [GO:0003824]	bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by host of viral process [GO:0044794]; positive regulation of multicellular organism growth [GO:0040018]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]		cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; unfolded protein binding [GO:0051082]	catalytic activity [GO:0003824]
d3icka__d2ps6b___1		Fungi		Ascomycota	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	sesquiterpenoid biosynthetic process [GO:0016106]			dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]
d3idaa1_d3esda___1		Fungi	Actinobacteria	Ascomycota	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	cocaine catabolic process [GO:0050784]		cytoplasm [GO:0005737]	extracellular region [GO:0005576]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]	cutinase activity [GO:0050525]
d3idga1_d1mcia2__1												
d3idia1_d4pjfe1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3idia2_d3gm0a1__1												
d3idja1_d2b4ch2__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3idja2_d5wtga1__1												
d3idma2_d2ai0n2__1		Metazoa		Chordata								
d3idoa1_d2ipab___1				Firmicutes	protein tyrosine phosphatase activity [GO:0004725]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	protein tyrosine phosphatase activity [GO:0004725]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d3idsa2_d1nptq2__1				Firmicutes	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	glycosome [GO:0020015]	cytoplasm [GO:0005737]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3idsc2_d3gpdr2__1		Metazoa		Chordata	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; canonical glycolysis [GO:0061621]; cellular response to interferon-gamma [GO:0071346]; defense response to fungus [GO:0050832]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; killing by host of symbiont cells [GO:0051873]; killing of cells of other organism [GO:0031640]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of translation [GO:0017148]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction [GO:0052501]; positive regulation of cytokine secretion [GO:0050715]; protein stabilization [GO:0050821]; regulation of macroautophagy [GO:0016241]	glycosome [GO:0020015]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; GAIT complex [GO:0097452]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	aspartic-type endopeptidase inhibitor activity [GO:0019828]; disordered domain specific binding [GO:0097718]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; peptidyl-cysteine S-nitrosylase activity [GO:0035605]
d3idva1_d1n8jn___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; melanosome [GO:0042470]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide isomerase activity [GO:0003756]; RNA binding [GO:0003723]; cell redox homeostasis [GO:0045454]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein secretion [GO:0009306]; response to endoplasmic reticulum stress [GO:0034976]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein secretion [GO:0009306]; response to endoplasmic reticulum stress [GO:0034976]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; melanosome [GO:0042470]	cell [GO:0005623]; cytosol [GO:0005829]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide isomerase activity [GO:0003756]; RNA binding [GO:0003723]	thioredoxin peroxidase activity [GO:0008379]
d3idva1_d3zvjc1__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cell [GO:0005623]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; melanosome [GO:0042470]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide isomerase activity [GO:0003756]; RNA binding [GO:0003723]; cell redox homeostasis [GO:0045454]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein secretion [GO:0009306]; response to endoplasmic reticulum stress [GO:0034976]	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein secretion [GO:0009306]; response to endoplasmic reticulum stress [GO:0034976]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; melanosome [GO:0042470]	cell [GO:0005623]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide isomerase activity [GO:0003756]; RNA binding [GO:0003723]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d3idxl1_d1pqza1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; entry into host cell [GO:0030260]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; entry into host cell [GO:0030260]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3idzc__d5n0ia1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	rRNA processing [GO:0006364]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]	periplasmic space [GO:0042597]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d3idzd__d3iemb___1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	rRNA processing [GO:0006364]	rRNA processing [GO:0006364]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3ie1a__d1k07b___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	beta-lactamase activity [GO:0008800]; metal ion binding [GO:0046872]	rRNA processing [GO:0006364]		cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	beta-lactamase activity [GO:0008800]; metal ion binding [GO:0046872]
d3ie1c__d4d02a1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; nitric oxide catabolic process [GO:0046210]; protein homotetramerization [GO:0051289]; response to nitric oxide [GO:0071731]	rRNA processing [GO:0006364]	nitric oxide catabolic process [GO:0046210]; protein homotetramerization [GO:0051289]; response to nitric oxide [GO:0071731]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]
d3ie2b__d3iemc___1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	rRNA processing [GO:0006364]	rRNA processing [GO:0006364]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3ie3a1_d1gsfb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3ie3b2_d2wjuf2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d3ie9a__d3nsca1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d3ieia__d5cvjb2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; C-terminal protein methylation [GO:0006481]; cellular protein modification process [GO:0006464]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]	cellular protein modification process [GO:0006464]; C-terminal protein methylation [GO:0006481]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]		cytosol [GO:0005829]; nucleoplasm [GO:0005654]		protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]
d3ieid__d5icea2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; C-terminal protein methylation [GO:0006481]; cellular protein modification process [GO:0006464]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	(RS)-norcoclaurine 6-O-methyltransferase activity [GO:0030786]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; alkaloid metabolic process [GO:0009820]	cellular protein modification process [GO:0006464]; C-terminal protein methylation [GO:0006481]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	alkaloid metabolic process [GO:0009820]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]		protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	(RS)-norcoclaurine 6-O-methyltransferase activity [GO:0030786]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]
d3ieif__d2hmyb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; C-terminal protein methylation [GO:0006481]; cellular protein modification process [GO:0006464]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	cellular protein modification process [GO:0006464]; C-terminal protein methylation [GO:0006481]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	DNA restriction-modification system [GO:0009307]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]		protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d3ieja1_d1gx3c___1	Metazoa		Chordata	Actinobacteria	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	arylamine N-acetyltransferase activity [GO:0004060]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	arylamine N-acetyltransferase activity [GO:0004060]
d3iejb1_d3bpfb___1	Metazoa		Chordata	Apicomplexa	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	integral component of membrane [GO:0016021]; cysteine-type peptidase activity [GO:0008234]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	cysteine-type peptidase activity [GO:0008234]
d3iekb__d4bp0d___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]	rRNA processing [GO:0006364]	antibiotic catabolic process [GO:0017001]	cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d3iekd__d5ls3b___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]	rRNA processing [GO:0006364]	antibiotic catabolic process [GO:0017001]	cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d3iela__d2m5ca___1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	rRNA processing [GO:0006364]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]	periplasmic space [GO:0042597]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d3ielb__d2zddb___1			Deinococcus-Thermus		cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]		rRNA processing [GO:0006364]		cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	
d3iema__d2ohij1__1			Deinococcus-Thermus	Euryarchaeota	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	rRNA processing [GO:0006364]		cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d3iemb__d1kr3a___1			Deinococcus-Thermus	Bacteroidetes	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	rRNA processing [GO:0006364]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]	periplasmic space [GO:0042597]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d3iemc__d4pvtb___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	metal ion binding [GO:0046872]	rRNA processing [GO:0006364]		cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	metal ion binding [GO:0046872]
d3iemd__d1ychc2__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	rRNA processing [GO:0006364]		cytoplasm [GO:0005737]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d3ieta1_d5x2nl2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; integral component of membrane [GO:0016021]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge of lamellipodium [GO:0061851]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; tetraspanin-enriched microdomain [GO:0097197]; chaperone binding [GO:0051087]; chemokine binding [GO:0019956]; signaling receptor binding [GO:0005102]; actin-mediated cell contraction [GO:0070252]; amino acid transmembrane transport [GO:0003333]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; folic acid transport [GO:0015884]; invadopodium organization [GO:1905863]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lymph node development [GO:0048535]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell fate commitment [GO:0060838]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular component movement [GO:0051272]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of platelet activation [GO:0010572]; positive regulation of platelet aggregation [GO:1901731]; prostaglandin metabolic process [GO:0006693]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of myofibroblast contraction [GO:1904328]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; tube morphogenesis [GO:0035239]; visceral serous pericardium development [GO:0061032]; water transport [GO:0006833]; wound healing, spreading of cells [GO:0044319]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; G protein-coupled receptor activity [GO:0004930]	actin-mediated cell contraction [GO:0070252]; amino acid transmembrane transport [GO:0003333]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; folic acid transport [GO:0015884]; invadopodium organization [GO:1905863]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell fate commitment [GO:0060838]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular component movement [GO:0051272]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of platelet activation [GO:0010572]; positive regulation of platelet aggregation [GO:1901731]; prostaglandin metabolic process [GO:0006693]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of myofibroblast contraction [GO:1904328]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; tube morphogenesis [GO:0035239]; visceral serous pericardium development [GO:0061032]; water transport [GO:0006833]; wound healing, spreading of cells [GO:0044319]		apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; integral component of membrane [GO:0016021]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge of lamellipodium [GO:0061851]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; tetraspanin-enriched microdomain [GO:0097197]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	chaperone binding [GO:0051087]; chemokine binding [GO:0019956]; signaling receptor binding [GO:0005102]	G protein-coupled receptor activity [GO:0004930]
d3ieta2_d5sx4l1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; integral component of membrane [GO:0016021]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge of lamellipodium [GO:0061851]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; tetraspanin-enriched microdomain [GO:0097197]; chaperone binding [GO:0051087]; chemokine binding [GO:0019956]; signaling receptor binding [GO:0005102]; actin-mediated cell contraction [GO:0070252]; amino acid transmembrane transport [GO:0003333]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; folic acid transport [GO:0015884]; invadopodium organization [GO:1905863]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lymph node development [GO:0048535]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell fate commitment [GO:0060838]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular component movement [GO:0051272]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of platelet activation [GO:0010572]; positive regulation of platelet aggregation [GO:1901731]; prostaglandin metabolic process [GO:0006693]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of myofibroblast contraction [GO:1904328]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; tube morphogenesis [GO:0035239]; visceral serous pericardium development [GO:0061032]; water transport [GO:0006833]; wound healing, spreading of cells [GO:0044319]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	actin-mediated cell contraction [GO:0070252]; amino acid transmembrane transport [GO:0003333]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; folic acid transport [GO:0015884]; invadopodium organization [GO:1905863]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell fate commitment [GO:0060838]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular component movement [GO:0051272]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of platelet activation [GO:0010572]; positive regulation of platelet aggregation [GO:1901731]; prostaglandin metabolic process [GO:0006693]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of myofibroblast contraction [GO:1904328]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; tube morphogenesis [GO:0035239]; visceral serous pericardium development [GO:0061032]; water transport [GO:0006833]; wound healing, spreading of cells [GO:0044319]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; integral component of membrane [GO:0016021]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge of lamellipodium [GO:0061851]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; tetraspanin-enriched microdomain [GO:0097197]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	chaperone binding [GO:0051087]; chemokine binding [GO:0019956]; signaling receptor binding [GO:0005102]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d3ietc2_d5c9ke1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; integral component of membrane [GO:0016021]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge of lamellipodium [GO:0061851]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; tetraspanin-enriched microdomain [GO:0097197]; chaperone binding [GO:0051087]; chemokine binding [GO:0019956]; signaling receptor binding [GO:0005102]; actin-mediated cell contraction [GO:0070252]; amino acid transmembrane transport [GO:0003333]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; folic acid transport [GO:0015884]; invadopodium organization [GO:1905863]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lymph node development [GO:0048535]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell fate commitment [GO:0060838]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular component movement [GO:0051272]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of platelet activation [GO:0010572]; positive regulation of platelet aggregation [GO:1901731]; prostaglandin metabolic process [GO:0006693]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of myofibroblast contraction [GO:1904328]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; tube morphogenesis [GO:0035239]; visceral serous pericardium development [GO:0061032]; water transport [GO:0006833]; wound healing, spreading of cells [GO:0044319]		actin-mediated cell contraction [GO:0070252]; amino acid transmembrane transport [GO:0003333]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; folic acid transport [GO:0015884]; invadopodium organization [GO:1905863]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell fate commitment [GO:0060838]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular component movement [GO:0051272]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of platelet activation [GO:0010572]; positive regulation of platelet aggregation [GO:1901731]; prostaglandin metabolic process [GO:0006693]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of myofibroblast contraction [GO:1904328]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; tube morphogenesis [GO:0035239]; visceral serous pericardium development [GO:0061032]; water transport [GO:0006833]; wound healing, spreading of cells [GO:0044319]		apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; filopodium [GO:0030175]; filopodium membrane [GO:0031527]; integral component of membrane [GO:0016021]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge of lamellipodium [GO:0061851]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; tetraspanin-enriched microdomain [GO:0097197]		chaperone binding [GO:0051087]; chemokine binding [GO:0019956]; signaling receptor binding [GO:0005102]	
d3ieua1_d2hyii1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; small ribosomal subunit rRNA binding [GO:0070181]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]	protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; ribosomal small subunit assembly [GO:0000028]; ribosomal small subunit biogenesis [GO:0042274]	mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; plasma membrane [GO:0005886]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; exon-exon junction complex [GO:0035145]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U2-type catalytic step 1 spliceosome [GO:0071006]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; rRNA binding [GO:0019843]; small ribosomal subunit rRNA binding [GO:0070181]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d3if1a2_d1fcca1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3if1c1_d5k65b2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3if1c2_d5eblb1__1				Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d3ifba__d5hzqa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	intestinal lipid absorption [GO:0098856]; triglyceride catabolic process [GO:0019433]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytosol [GO:0005829]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3ifgb1_d4kwgc___1		Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3ifgb1_d5gtkc___1				Firmicutes		aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]						aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]
d3ifgc1_d4zulg___1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]; cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]		cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]
d3ifgg1_d4h73c___1				Crenarchaeota		nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]						nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3ifgh1_d2onml___1		Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3ifgj1_d2esdd___1				Firmicutes		glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]						glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]
d3ifgj1_d4cbba___1				Proteobacteria		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]		glycine betaine biosynthetic process from choline [GO:0019285]				aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]
d3ifgk1_d4fr8c___1		Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3ifgk1_d4nu9b___1				Firmicutes		betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; glycine betaine biosynthetic process from choline [GO:0019285]		glycine betaine biosynthetic process from choline [GO:0019285]				betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d3ifgl1_d4i3va___1				Proteobacteria		nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]						nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3ifh11_d2euha___1				Firmicutes		glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]						glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]
d3ifh31_d1bxsb___1		Metazoa		Chordata		cytosol [GO:0005829]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]
d3ifh31_d4ogda___1				Firmicutes		nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]						nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3ifh51_d1uxpa___1				Crenarchaeota		glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]						glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3ifhr1_d3rhmd___1		Metazoa		Chordata		cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]
d3ifhu1_d2onpc___1		Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3ifhy1_d5l2og___1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; androgen binding [GO:0005497]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; GTPase activator activity [GO:0005096]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; cellular aldehyde metabolic process [GO:0006081]; ethanol oxidation [GO:0006069]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; negative regulation of cold-induced thermogenesis [GO:0120163]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cellular aldehyde metabolic process [GO:0006081]; ethanol oxidation [GO:0006069]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; negative regulation of cold-induced thermogenesis [GO:0120163]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; androgen binding [GO:0005497]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; GTPase activator activity [GO:0005096]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]
d3igaa2_d3qxvc___1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d3igab1_d1igyd1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	voltage-gated potassium channel complex [GO:0008076]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3igab1_d1w72l2__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	voltage-gated potassium channel complex [GO:0008076]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3igab2_d5lspl1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; hepatocyte growth factor-activated receptor activity [GO:0005008]; identical protein binding [GO:0042802]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; semaphorin receptor activity [GO:0017154]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; branching morphogenesis of an epithelial tube [GO:0048754]; cell surface receptor signaling pathway [GO:0007166]; endothelial cell morphogenesis [GO:0001886]; entry of bacterium into host cell [GO:0035635]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of autophagy [GO:0010507]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		branching morphogenesis of an epithelial tube [GO:0048754]; cell surface receptor signaling pathway [GO:0007166]; endothelial cell morphogenesis [GO:0001886]; entry of bacterium into host cell [GO:0035635]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of autophagy [GO:0010507]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	voltage-gated potassium channel complex [GO:0008076]	basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	ATP binding [GO:0005524]; hepatocyte growth factor-activated receptor activity [GO:0005008]; identical protein binding [GO:0042802]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; semaphorin receptor activity [GO:0017154]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3igua2_d3lxcb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d3igub1_d1ghol5__1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]		carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]	
d3igub1_d2qpuc2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	extracellular space [GO:0005615]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d3igub2_d3ueqa2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]	amylosucrase activity [GO:0047669]
d3ihhc__d5noob___1		Metazoa		Nematoda (roundworms)		thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]		dTMP biosynthetic process [GO:0006231]				thymidylate synthase activity [GO:0004799]
d3ihhe__d3ob7e___1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]		aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; DNA biosynthetic process [GO:0071897]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; nucleobase-containing small molecule interconversion [GO:0015949]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]		cofactor binding [GO:0048037]; folic acid binding [GO:0005542]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3ihia__d2aazc___1	Metazoa	Fungi	Chordata	Basidiomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; mRNA binding [GO:0003729]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; regulation of translation [GO:0006417]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; negative regulation of translation [GO:0017148]; regulation of translation [GO:0006417]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cofactor binding [GO:0048037]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; mRNA binding [GO:0003729]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	thymidylate synthase activity [GO:0004799]
d3ihnb__d1i0db___1				Proteobacteria		plasma membrane [GO:0005886]; aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]; catabolic process [GO:0009056]		catabolic process [GO:0009056]		plasma membrane [GO:0005886]		aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]
d3ihnc__d3hk8a___1				Firmicutes		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d3ihnd__d1k6wa2__1				Proteobacteria		cytosol [GO:0005829]; 5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; isoguanine deaminase activity [GO:0035888]; zinc ion binding [GO:0008270]; cytosine catabolic process [GO:0006209]		cytosine catabolic process [GO:0006209]		cytosol [GO:0005829]		5-fluorocytosine deaminase activity [GO:0102480]; cytosine deaminase activity [GO:0004131]; ferrous iron binding [GO:0008198]; identical protein binding [GO:0042802]; isoguanine deaminase activity [GO:0035888]; zinc ion binding [GO:0008270]
d3ihoa__d1lmza___1	Metazoa		Chordata	Proteobacteria	chromatin [GO:0000785]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; endodeoxyribonuclease activity [GO:0004520]; pyrimidine-specific mismatch base pair DNA N-glycosylase activity [GO:0008263]; satellite DNA binding [GO:0003696]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; response to estradiol [GO:0032355]; response to radiation [GO:0009314]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]	depyrimidination [GO:0045008]; DNA repair [GO:0006281]; response to estradiol [GO:0032355]; response to radiation [GO:0009314]	base-excision repair [GO:0006284]	chromatin [GO:0000785]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		DNA binding [GO:0003677]; DNA N-glycosylase activity [GO:0019104]; endodeoxyribonuclease activity [GO:0004520]; pyrimidine-specific mismatch base pair DNA N-glycosylase activity [GO:0008263]; satellite DNA binding [GO:0003696]	DNA-3-methyladenine glycosylase activity [GO:0008725]; metal ion binding [GO:0046872]
d3ihqa__d4yh2a1__1		Metazoa	Firmicutes	Arthropoda	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	transcription, DNA-templated [GO:0006351]	glutathione metabolic process [GO:0006749]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; protein dimerization activity [GO:0046983]	glutathione transferase activity [GO:0004364]
d3ihza__d4j4nc___1			Apicomplexa	Apicomplexa	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein dimerization activity [GO:0046983]; chaperone-mediated protein folding [GO:0061077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]		chaperone-mediated protein folding [GO:0061077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein dimerization activity [GO:0046983]
d3ii0a1_d1pmmb___1	Metazoa		Chordata	Proteobacteria	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; carboxylic acid binding [GO:0031406]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; phosphatidylserine decarboxylase activity [GO:0004609]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; fatty acid homeostasis [GO:0055089]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of mitochondrial depolarization [GO:0051902]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; response to cadmium ion [GO:0046686]; response to carbohydrate [GO:0009743]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to transition metal nanoparticle [GO:1990267]; transdifferentiation [GO:0060290]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; fatty acid homeostasis [GO:0055089]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of mitochondrial depolarization [GO:0051902]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; response to cadmium ion [GO:0046686]; response to carbohydrate [GO:0009743]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to transition metal nanoparticle [GO:1990267]; transdifferentiation [GO:0060290]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	carboxylic acid binding [GO:0031406]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; phosphatidylserine decarboxylase activity [GO:0004609]; pyridoxal phosphate binding [GO:0030170]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]
d3ii0c1_d1wyuf___1	Metazoa		Chordata	Deinococcus-Thermus	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; carboxylic acid binding [GO:0031406]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; phosphatidylserine decarboxylase activity [GO:0004609]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; fatty acid homeostasis [GO:0055089]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of mitochondrial depolarization [GO:0051902]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; response to cadmium ion [GO:0046686]; response to carbohydrate [GO:0009743]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to transition metal nanoparticle [GO:1990267]; transdifferentiation [GO:0060290]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]; glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; fatty acid homeostasis [GO:0055089]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of mitochondrial depolarization [GO:0051902]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; response to cadmium ion [GO:0046686]; response to carbohydrate [GO:0009743]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to transition metal nanoparticle [GO:1990267]; transdifferentiation [GO:0060290]	glycine decarboxylation via glycine cleavage system [GO:0019464]; nucleoside metabolic process [GO:0009116]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		carboxylic acid binding [GO:0031406]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; phosphatidylserine decarboxylase activity [GO:0004609]; pyridoxal phosphate binding [GO:0030170]	glycine dehydrogenase (decarboxylating) activity [GO:0004375]
d3ii0d1_d5x2wa___1	Metazoa		Chordata	Proteobacteria	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; carboxylic acid binding [GO:0031406]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; phosphatidylserine decarboxylase activity [GO:0004609]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; fatty acid homeostasis [GO:0055089]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of mitochondrial depolarization [GO:0051902]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; response to cadmium ion [GO:0046686]; response to carbohydrate [GO:0009743]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to transition metal nanoparticle [GO:1990267]; transdifferentiation [GO:0060290]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; fatty acid homeostasis [GO:0055089]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of mitochondrial depolarization [GO:0051902]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; response to cadmium ion [GO:0046686]; response to carbohydrate [GO:0009743]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to transition metal nanoparticle [GO:1990267]; transdifferentiation [GO:0060290]	transsulfuration [GO:0019346]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		carboxylic acid binding [GO:0031406]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; phosphatidylserine decarboxylase activity [GO:0004609]; pyridoxal phosphate binding [GO:0030170]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d3ii0d1_d5xmrb___1	Metazoa		Chordata	Apicomplexa	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; carboxylic acid binding [GO:0031406]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; phosphatidylserine decarboxylase activity [GO:0004609]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; fatty acid homeostasis [GO:0055089]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of mitochondrial depolarization [GO:0051902]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; response to cadmium ion [GO:0046686]; response to carbohydrate [GO:0009743]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to transition metal nanoparticle [GO:1990267]; transdifferentiation [GO:0060290]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; fatty acid homeostasis [GO:0055089]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of mitochondrial depolarization [GO:0051902]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; response to cadmium ion [GO:0046686]; response to carbohydrate [GO:0009743]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to transition metal nanoparticle [GO:1990267]; transdifferentiation [GO:0060290]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	axon terminus [GO:0043679]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		carboxylic acid binding [GO:0031406]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-cysteine:2-oxoglutarate aminotransferase activity [GO:0047801]; phosphatidylserine decarboxylase activity [GO:0004609]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]
d3ii7a__d2xn4b___1	Metazoa	Metazoa	Chordata	Chordata	Cul3-RING ubiquitin ligase complex [GO:0031463]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein ubiquitination [GO:0016567]	actin cytoskeleton [GO:0015629]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; ruffle [GO:0001726]; actin binding [GO:0003779]; identical protein binding [GO:0042802]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]	protein ubiquitination [GO:0016567]	post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]	Cul3-RING ubiquitin ligase complex [GO:0031463]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; ruffle [GO:0001726]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; identical protein binding [GO:0042802]
d3ii9a2_d1ivhb1__1		Metazoa	Proteobacteria	Chordata	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA hydrolase activity [GO:0044466]	mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; isovaleryl-CoA dehydrogenase activity [GO:0008470]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552]		branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552]		mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA hydrolase activity [GO:0044466]	flavin adenine dinucleotide binding [GO:0050660]; isovaleryl-CoA dehydrogenase activity [GO:0008470]
d3ii9c2_d3fcja2__1		Fungi	Proteobacteria	Ascomycota	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA hydrolase activity [GO:0044466]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]		nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]			acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA hydrolase activity [GO:0044466]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d3iiaa__d1o3ta2__1	Metazoa		Chordata	Proteobacteria	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3iida__d1lcpa1__1	Metazoa	Metazoa	Chordata	Chordata	Barr body [GO:0001740]; condensed chromosome [GO:0000793]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; sex chromatin [GO:0001739]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; enzyme binding [GO:0019899]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]; chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of response to oxidative stress [GO:1902883]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of response to oxidative stress [GO:1902884]; regulation of gene expression, epigenetic [GO:0040029]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]	chromatin organization [GO:0006325]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of protein localization to chromosome, telomeric region [GO:1904815]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of response to oxidative stress [GO:1902883]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of response to oxidative stress [GO:1902884]; regulation of gene expression, epigenetic [GO:0040029]; regulation of lipid metabolic process [GO:0019216]; regulation of response to oxidative stress [GO:1902882]		Barr body [GO:0001740]; condensed chromosome [GO:0000793]; extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; sex chromatin [GO:0001739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; double-stranded methylated DNA binding [GO:0010385]; enzyme binding [GO:0019899]; nucleosomal DNA binding [GO:0031492]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein serine/threonine kinase inhibitor activity [GO:0030291]; rDNA binding [GO:0000182]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription regulatory region DNA binding [GO:0044212]	aminopeptidase activity [GO:0004177]; disordered domain specific binding [GO:0097718]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; peptidase activity [GO:0008233]
d3ij5d__d1wvia___1			Proteobacteria	Firmicutes	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]				3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	
d3ij6a1_d1i0bb___1			Firmicutes	Proteobacteria	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	plasma membrane [GO:0005886]; aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]; catabolic process [GO:0009056]		catabolic process [GO:0009056]		plasma membrane [GO:0005886]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	aryldialkylphosphatase activity [GO:0004063]; zinc ion binding [GO:0008270]
d3ij7a1_d4uzua1__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d3ij8a1_d1qi0a___1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cellulose catabolic process [GO:0030245]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]
d3ij9a2_d1vfub2__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d3ijfx__d5cqha1__1		Metazoa	Actinobacteria	Chordata	cytosol [GO:0005829]; plasma membrane [GO:0005886]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; pyrimidine nucleobase salvage [GO:0043100]; uridine biosynthetic process [GO:0046109]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]	cytidine deamination [GO:0009972]; pyrimidine nucleobase salvage [GO:0043100]; uridine biosynthetic process [GO:0046109]	cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3ijha2_d3lh2o___1												
d3ijhc1_d2a9mh___1												
d3ijhc2_d4p4rc2__1		Metazoa		Chordata		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]		cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d3ijoe__d3a3ua___1	Metazoa		Chordata	Deinococcus-Thermus	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbon-carbon lyase activity [GO:0016830]; menaquinone biosynthetic process [GO:0009234]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	menaquinone biosynthetic process [GO:0009234]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbon-carbon lyase activity [GO:0016830]
d3ijoe__d4exla___1	Metazoa		Chordata	Firmicutes	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	plasma membrane [GO:0005886]; phosphate ion binding [GO:0042301]; phosphate ion transport [GO:0006817]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	phosphate ion transport [GO:0006817]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	plasma membrane [GO:0005886]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	phosphate ion binding [GO:0042301]
d3ijsa1_d3b5hc1__1		Metazoa		Chordata		acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]		axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; decidualization [GO:0046697]; dendrite self-avoidance [GO:0070593]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of interleukin-6 production [GO:0032755]; protein localization to plasma membrane [GO:0072659]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]		acrosomal membrane [GO:0002080]; axon [GO:0030424]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]		cadherin binding [GO:0045296]; cell-cell adhesion mediator activity [GO:0098632]; mannose binding [GO:0005537]
d3ijua__d1flwa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3ijva__d1cupa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3ijva__d1lzga___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3ijya1_d3mbxl2__1												
d3ijya2_d1igjc1__1												
d3ik4b1_d3dg6a1__1			Chloroflexi	Actinobacteria	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	peptide metabolic process [GO:0006518]				magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3ik4d2_d4a3rb2__1			Chloroflexi	Firmicutes	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]; sporulation resulting in formation of a cellular spore [GO:0030435]	peptide metabolic process [GO:0006518]	glycolytic process [GO:0006096]; sporulation resulting in formation of a cellular spore [GO:0030435]		cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3ik7a2_d6gswb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d3ik7b1_d2l5la1__1	Metazoa		Chordata	Bacteroidetes	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytosol [GO:0005829]	cell [GO:0005623]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	protein disulfide oxidoreductase activity [GO:0015035]
d3ik7c2_d4l5la2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]		glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d3ik7d1_d2v6ka1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; maleylpyruvate isomerase activity [GO:0050077]; aromatic amino acid family metabolic process [GO:0009072]; aromatic compound catabolic process [GO:0019439]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	aromatic amino acid family metabolic process [GO:0009072]; aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	maleylpyruvate isomerase activity [GO:0050077]
d3ik7d2_d4e8ea2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]		glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	transferase activity [GO:0016740]
d3ik9a1_d3s9fa___1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytosol [GO:0005829]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	
d3ik9c2_d2oadb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]
d3ik9f1_d1fb6b___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; chloroplast [GO:0009507]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; chloroplast [GO:0009507]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	protein disulfide oxidoreductase activity [GO:0015035]
d3ik9f2_d5ecsa2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d3ik9g2_d2c3nb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]
d3ik9h1_d4k7ob___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; inflammatory response [GO:0006954]; NADPH oxidation [GO:0070995]; negative regulation of apoptotic process [GO:0043066]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription by RNA polymerase III [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	antioxidant activity [GO:0016209]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; peroxynitrite reductase activity [GO:0072541]; protein dimerization activity [GO:0046983]; RNA polymerase III regulatory region DNA binding [GO:0001016]; signaling receptor binding [GO:0005102]; thioredoxin peroxidase activity [GO:0008379]
d3ikcc1_d5cd3f1__1												
d3ikea__d5iwxc___1			Proteobacteria	Firmicutes	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d3ikfa__d1iv1d___1			Proteobacteria	Deinococcus-Thermus	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d3ikja3_d5ik2n3__1			Euryarchaeota	Firmicutes	ATP binding [GO:0005524]; endonuclease activity [GO:0004519]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]		plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; endonuclease activity [GO:0004519]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3ikla1_d4eo4d2__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; mitochondrial threonyl-tRNA aminoacylation [GO:0070159]; threonyl-tRNA aminoacylation [GO:0006435]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	mitochondrial threonyl-tRNA aminoacylation [GO:0070159]; threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]
d3iklb1_d1kmnb1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	cytosol [GO:0005829]; ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]; histidyl-tRNA aminoacylation [GO:0006427]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	histidyl-tRNA aminoacylation [GO:0006427]	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	ATP binding [GO:0005524]; histidine-tRNA ligase activity [GO:0004821]
d3iklb1_d4p3pb2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA-dependent DNA replication [GO:0006261]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; in utero embryonic development [GO:0001701]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005]; respiratory electron transport chain [GO:0022904]	negative regulation of translational initiation [GO:0045947]; regulation of translation [GO:0006417]; response to antibiotic [GO:0046677]; threonyl-tRNA aminoacylation [GO:0006435]; tRNA aminoacylation [GO:0043039]; tRNA aminoacylation for protein translation [GO:0006418]	cytoplasm [GO:0005737]; gamma DNA polymerase complex [GO:0005760]; mitochondrial chromosome [GO:0000262]; mitochondrial matrix [GO:0005759]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	aminoacyl-tRNA editing activity [GO:0002161]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; drug binding [GO:0008144]; mRNA 5'-UTR binding [GO:0048027]; RNA binding [GO:0003723]; threonine-tRNA ligase activity [GO:0004829]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d3iknb2_d4ak8d___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d3iknc2_d3c22c___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d3ikpb2_d1kza1___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]
d3ikqb2_d2bphb1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	cellular response to molecule of fungal origin [GO:0071226]; cytokine production involved in immune response [GO:0002367]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte activation involved in immune response [GO:0002366]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of stress-activated MAPK cascade [GO:0032874]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3ikrc2_d1ypoa___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d3ikvb1_d1ixrc1__1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	cytoplasm [GO:0005737]		coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; four-way junction helicase activity [GO:0009378]
d3ikvb1_d3pqjc___1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]	negative regulation of transcription, DNA-templated [GO:0045892]	cytoplasm [GO:0005737]	protein-DNA complex [GO:0032993]	coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3il3a2_d1m1ta2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3il7a2_d2buha2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d3il7a2_d3u0fa2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d3il7b1_d2iikb2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; specific granule lumen [GO:0035580]; acetate CoA-transferase activity [GO:0008775]; acetyl-CoA C-acyltransferase activity [GO:0003988]; palmitoyl-CoA oxidase activity [GO:0016401]; alpha-linolenic acid metabolic process [GO:0036109]; bile acid metabolic process [GO:0008206]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; neutrophil degranulation [GO:0043312]; phenylacetate catabolic process [GO:0010124]; protein targeting to peroxisome [GO:0006625]; very long-chain fatty acid metabolic process [GO:0000038]	fatty acid biosynthetic process [GO:0006633]	alpha-linolenic acid metabolic process [GO:0036109]; bile acid metabolic process [GO:0008206]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; neutrophil degranulation [GO:0043312]; phenylacetate catabolic process [GO:0010124]; protein targeting to peroxisome [GO:0006625]; very long-chain fatty acid metabolic process [GO:0000038]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular region [GO:0005576]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; specific granule lumen [GO:0035580]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA C-acyltransferase activity [GO:0003988]; palmitoyl-CoA oxidase activity [GO:0016401]
d3il9a2_d1oxhc2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d3il9b2_d1h4fc1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d3ilia__d4m5ia___1			Proteobacteria	Proteobacteria	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]			2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [GO:0003848]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]
d3ilna__d2jecb1__1		Viridiplantae	Bacteroidetes	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3ilna__d3pmea1__1			Bacteroidetes	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]	negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]
d3ilpb__d3arec1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ilqd__d3sdcd2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ilth__d3seya1__1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3ilub__d2v25a___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell surface [GO:0009986]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell surface [GO:0009986]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d3iluh__d3pd8a___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3imda__d3vs7a2__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]
d3imga__d4zcsc___1			Actinobacteria	Apicomplexa	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]; beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	choline-phosphate cytidylyltransferase activity [GO:0004105]; identical protein binding [GO:0042802]; phosphatidylcholine binding [GO:0031210]	beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]		cytosol [GO:0005829]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]	choline-phosphate cytidylyltransferase activity [GO:0004105]; identical protein binding [GO:0042802]; phosphatidylcholine binding [GO:0031210]
d3imja__d2qmsd___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cell projection [GO:0042995]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; axon guidance [GO:0007411]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; leukocyte migration [GO:0050900]; negative regulation of translation [GO:0017148]; positive regulation of cell migration [GO:0030335]; stress granule assembly [GO:0034063]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	axon guidance [GO:0007411]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; leukocyte migration [GO:0050900]; negative regulation of translation [GO:0017148]; positive regulation of cell migration [GO:0030335]; stress granule assembly [GO:0034063]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	cell projection [GO:0042995]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	identical protein binding [GO:0042802]; phosphatidylinositol binding [GO:0035091]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]
d3imlb3_d1p7ld3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d3imld2_d4kttd1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d3imld2_d4odja2__1			Proteobacteria		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]		one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]	
d3imtb__d3i9ib___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3imub__d3cyka___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]		cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]		hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	
d3imwb__d1ijnb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3imxa2_d1x9ja2__1	Metazoa		Chordata	Thermotogae	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]		cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]	ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]
d3imzc__d2dgmd___1				Proteobacteria		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]		glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]
d3in0c__d3uaba1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d3in0d__d1bawc___1			Proteobacteria	Cyanobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	thylakoid membrane [GO:0042651]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3inja__d4i25a___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3injf__d4i3uc___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3inlc__d1uxra___1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3inle__d2xdrc___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glycine betaine biosynthetic process from choline [GO:0019285]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]
d3inlg__d4i3ve___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3inna1_d2cyba___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]; pantothenate biosynthetic process [GO:0015940]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	pantothenate biosynthetic process [GO:0015940]	tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]
d3inul1_d5jo4d1__1												
d3inul2_d4ezmf2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d3inxa__d2iora1__1	Metazoa		Chordata	Proteobacteria	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; cellular response to DNA damage stimulus [GO:0006974]; protein folding [GO:0006457]; response to heat [GO:0009408]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cellular response to DNA damage stimulus [GO:0006974]; protein folding [GO:0006457]; response to heat [GO:0009408]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]
d3inzc__d5szdl1__1			Proteobacteria	Aquificae	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]; RNA binding [GO:0003723]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]	cytosol [GO:0005829]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3inzd__d3m4gk___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]	cytosol [GO:0005829]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3inzf__d2ylbc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]	cytosol [GO:0005829]	RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d3ioba__d3kt6c___1		Fungi	Actinobacteria	Ascomycota	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]; beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	tryptophanyl-tRNA aminoacylation [GO:0006436]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d3ioga__d1xm8a1__1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	mitochondrion [GO:0005739]; hydroxyacylglutathione hydrolase activity [GO:0004416]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	periplasmic space [GO:0042597]	mitochondrion [GO:0005739]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	hydroxyacylglutathione hydrolase activity [GO:0004416]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]
d3iomb__d5mx6f___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; purine-nucleoside phosphorylase activity [GO:0004731]; deoxyguanosine catabolic process [GO:0006161]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	deoxyguanosine catabolic process [GO:0006161]	purine nucleoside metabolic process [GO:0042278]	cytoplasm [GO:0005737]		purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d3iosa__d1oc9a___1			Actinobacteria		cell [GO:0005623]; antioxidant activity [GO:0016209]; thiol oxidase activity [GO:0016972]; cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	antioxidant activity [GO:0016209]; thiol oxidase activity [GO:0016972]	
d3iosa__d3a3tf1__1			Actinobacteria	Proteobacteria	cell [GO:0005623]; antioxidant activity [GO:0016209]; thiol oxidase activity [GO:0016972]; cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	antioxidant activity [GO:0016209]; thiol oxidase activity [GO:0016972]	
d3ip5a1_d1ba2b___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; amino acid transport [GO:0006865]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; monosaccharide binding [GO:0048029]; D-ribose transmembrane transport [GO:0015752]; positive chemotaxis [GO:0050918]	amino acid transport [GO:0006865]	D-ribose transmembrane transport [GO:0015752]; positive chemotaxis [GO:0050918]		membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]	monosaccharide binding [GO:0048029]
d3ip5a1_d4rk0c___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; amino acid transport [GO:0006865]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	amino acid transport [GO:0006865]	regulation of transcription, DNA-templated [GO:0006355]			metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d3ip9a1_d2o20e___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; amino acid transport [GO:0006865]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]	amino acid transport [GO:0006865]	negative regulation of transcription, DNA-templated [GO:0045892]		protein-DNA complex [GO:0032993]	metal ion binding [GO:0046872]	DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3ip9a1_d3cs3a___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; amino acid transport [GO:0006865]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	amino acid transport [GO:0006865]	regulation of transcription, DNA-templated [GO:0006355]			metal ion binding [GO:0046872]	DNA binding [GO:0003677]
d3ipeb__d2iglb1__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	periplasmic space [GO:0042597]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]
d3iprc__d5t3ub1__1			Firmicutes	Firmicutes	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]	
d3iprf__d3lfha___1			Firmicutes	Firmicutes	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]	transferase activity [GO:0016740]
d3ipza__d3sbcc___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	cell [GO:0005623]; chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; antiporter activity [GO:0015297]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cation transport [GO:0006812]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]; identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]; cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cation transport [GO:0006812]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]	2 iron, 2 sulfur cluster binding [GO:0051537]; antiporter activity [GO:0015297]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]	identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]
d3iq3a__d1m8td___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; defense response to bacterium [GO:0042742]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d3iq5b__d2j8wa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3iq5c__d5l32c___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3iq5d__d1mqvb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3iq6a__d5gyrf___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3iq6b__d5jraa1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3iq6c__d3zqya___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3iq6e__d1qq3a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3iq6e__d5gyrm___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3iq6g__d2xl6a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3iq6g__d3hnih___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3iq6h__d2xm0a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3iqka__d4jsaa___1		Metazoa		Chordata		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3iqoa__d1mxeb___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	cell [GO:0005623]; cell cortex [GO:0005938]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; myosin V complex [GO:0031475]; myosin VI complex [GO:0031476]; nucleoplasm [GO:0005654]; rhabdomere [GO:0016028]; spindle [GO:0005819]; calcium ion binding [GO:0005509]; myosin heavy chain binding [GO:0032036]; myosin V binding [GO:0031489]; myosin VI head/neck binding [GO:0070855]; actin filament-based movement [GO:0030048]; adaptation of rhodopsin mediated signaling [GO:0016062]; calcium-mediated signaling [GO:0019722]; cellular response to ethanol [GO:0071361]; centriole replication [GO:0007099]; deactivation of rhodopsin mediated signaling [GO:0016059]; kinetochore organization [GO:0051383]; metarhodopsin inactivation [GO:0016060]; muscle cell cellular homeostasis [GO:0046716]; photoreceptor cell axon guidance [GO:0072499]; positive regulation of cation channel activity [GO:2001259]; protein phosphorylation [GO:0006468]; regulation of light-activated channel activity [GO:0016061]; rhabdomere development [GO:0042052]; rhodopsin mediated signaling pathway [GO:0016056]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	actin filament-based movement [GO:0030048]; adaptation of rhodopsin mediated signaling [GO:0016062]; calcium-mediated signaling [GO:0019722]; cellular response to ethanol [GO:0071361]; centriole replication [GO:0007099]; deactivation of rhodopsin mediated signaling [GO:0016059]; kinetochore organization [GO:0051383]; metarhodopsin inactivation [GO:0016060]; muscle cell cellular homeostasis [GO:0046716]; photoreceptor cell axon guidance [GO:0072499]; positive regulation of cation channel activity [GO:2001259]; protein phosphorylation [GO:0006468]; regulation of light-activated channel activity [GO:0016061]; rhabdomere development [GO:0042052]; rhodopsin mediated signaling pathway [GO:0016056]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cell [GO:0005623]; cell cortex [GO:0005938]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; mitotic spindle pole [GO:0097431]; myosin V complex [GO:0031475]; myosin VI complex [GO:0031476]; nucleoplasm [GO:0005654]; rhabdomere [GO:0016028]; spindle [GO:0005819]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; myosin heavy chain binding [GO:0032036]; myosin V binding [GO:0031489]; myosin VI head/neck binding [GO:0070855]
d3iqob__d1odbc1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cytokine secretion [GO:0050663]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; mast cell activation [GO:0045576]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]
d3iqsa__d2b3za2__1	Metazoa		Chordata	Firmicutes	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	riboflavin biosynthetic process [GO:0009231]	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]		cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d3ir1b__d3ttlb___1			Proteobacteria	Proteobacteria		extracellular space [GO:0005615]; periplasmic space [GO:0042597]; spermidine binding [GO:0019809]; pathogenesis [GO:0009405]; polyamine transport [GO:0015846]		pathogenesis [GO:0009405]; polyamine transport [GO:0015846]		extracellular space [GO:0005615]; periplasmic space [GO:0042597]		spermidine binding [GO:0019809]
d3ir1d__d2zyka___1			Proteobacteria	Firmicutes		plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]				plasma membrane [GO:0005886]		carbohydrate transmembrane transporter activity [GO:0015144]
d3ir1e__d1mpca___1			Proteobacteria	Proteobacteria		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3ir2a__d2d30b___1	Metazoa		Chordata	Firmicutes	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]	base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]		apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]		cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]
d3ir2b__d2z3ha___1	Metazoa	Fungi	Chordata	Ascomycota	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	response to antibiotic [GO:0046677]	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]		cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d3ir5a1_d1ti6k2__1			Proteobacteria		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]	
d3ir6a2_d1vlfu1__1			Proteobacteria		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]	
d3ir7a2_d1g8kc1__1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]		integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]	3 iron, 4 sulfur cluster binding [GO:0051538]; arsenate reductase (azurin) activity [GO:0050611]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]
d3irga1_d1i7zc2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3irwp__d4tlqb___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of heart contraction [GO:0008016]; RNA processing [GO:0006396]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of heart contraction [GO:0008016]; RNA processing [GO:0006396]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]
d3irxa2_d4lsna2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3is7a__d2htna___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3is7k__d1oqua___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3is7l__d2y3qf___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3is7m__d2bjyk___1			Proteobacteria	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3is7r__d3qd8r1__1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3is7t__d3rbce___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3is7v__d1z6oc___1		Metazoa	Proteobacteria	Arthropoda	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3is7x__d3uoit___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3is8a__d1fz8a___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3is8c__d1bcfa___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3is8f__d1nf6n___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3is8g__d1fz0c___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3is8k__d1pfrb___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3is8o__d2jd7o___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3is8p__d5u1be___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; efflux transmembrane transporter activity [GO:0015562]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	efflux transmembrane transporter activity [GO:0015562]
d3is8q__d2iy4l___1			Proteobacteria	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; pathogenesis [GO:0009405]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3is8r__d1j30b___1			Proteobacteria	Crenarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d3is8s__d4kvsa___1			Proteobacteria	Cyanobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]
d3is8t__d3rn9b___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d3is8v__d1kgob___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3isea__d1piya___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3isec__d2g4ha___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3ised__d5d8qg___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3isee__d4m1id1__1			Proteobacteria	Chlamydiae	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3iseh__d3e1oe___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3isei__d4toeh___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3isej__d2v2ja___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3isek__d2cf7b___1			Proteobacteria	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d3isel__d3ak9k___1			Proteobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	
d3isem__d1o9ib___1			Proteobacteria	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]
d3iseq__d2jd84___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3iseq__d3e1mc___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3iser__d1bcfd___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3isev__d2yjkg___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3isev__d4xkuk___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3isfa__d2yjkd___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3isfb__d4cybc___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3isfd__d2jd7w___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3isfe__d3e1jd___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3isfe__d5l89z___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]
d3isja__d1mb2a___1			Actinobacteria	Firmicutes	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]; beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	tryptophanyl-tRNA aminoacylation [GO:0006436]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d3isnc2_d5fdla2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3isoa1_d3hvsa___1	Metazoa		Platyhelminthes	Proteobacteria	metal ion binding [GO:0046872]; transferase activity [GO:0016740]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]
d3iswb__d1le5f1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3it8h__d1jh5d___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]
d3it8h__d4qqla___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	collagen trimer [GO:0005581]; extracellular region [GO:0005576]; identical protein binding [GO:0042802]; regulation of synapse organization [GO:0050807]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	regulation of synapse organization [GO:0050807]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	collagen trimer [GO:0005581]; extracellular region [GO:0005576]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]	identical protein binding [GO:0042802]
d3itab2_d1nj4a1__1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to drug [GO:0042493]	integral component of plasma membrane [GO:0005887]; beta-lactamase activity [GO:0008800]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall macromolecule metabolic process [GO:0044036]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan metabolic process [GO:0000270]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to drug [GO:0042493]	cell wall macromolecule metabolic process [GO:0044036]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan metabolic process [GO:0000270]; regulation of cell shape [GO:0008360]	integral component of plasma membrane [GO:0005887]	integral component of plasma membrane [GO:0005887]	carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]	beta-lactamase activity [GO:0008800]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]
d3itbc2_d1nzoa1__1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to drug [GO:0042493]	integral component of plasma membrane [GO:0005887]; beta-lactamase activity [GO:0008800]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall macromolecule metabolic process [GO:0044036]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan metabolic process [GO:0000270]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to drug [GO:0042493]	cell wall macromolecule metabolic process [GO:0044036]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan metabolic process [GO:0000270]; regulation of cell shape [GO:0008360]	integral component of plasma membrane [GO:0005887]	integral component of plasma membrane [GO:0005887]	carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]	beta-lactamase activity [GO:0008800]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]
d3iu1b2_d5u08b___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]; cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]	cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]
d3iu2b1_d1yred___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]; cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	N-acetyltransferase activity [GO:0008080]	cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]	N-acetyltransferase activity [GO:0008080]
d3iu4l1_d5grvl___1												
d3iuna1_d3muna1__1			Proteobacteria	Proteobacteria	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]					serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d3ivaa2_d5reqb2__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cobalamin binding [GO:0031419]; methionine synthase activity [GO:0008705]; protein methyltransferase activity [GO:0008276]; zinc ion binding [GO:0008270]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]	homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; tetrahydrofolate interconversion [GO:0035999]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		cobalamin binding [GO:0031419]; methionine synthase activity [GO:0008705]; protein methyltransferase activity [GO:0008276]; zinc ion binding [GO:0008270]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylmalonyl-CoA mutase activity [GO:0004494]
d3ivca__d1n2ga___1			Actinobacteria	Actinobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]; beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]; beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	beta-alanine metabolic process [GO:0019482]; pantothenate biosynthetic process [GO:0015940]; pantothenate biosynthetic process from valine [GO:0033317]; pathogenesis [GO:0009405]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; pantoate-beta-alanine ligase activity [GO:0004592]
d3ivkl1_d1im3f2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3iwea1_d4uwia1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]; cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	cytoplasm [GO:0005737]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]	cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	N-terminal peptidyl-glycine N-myristoylation [GO:0018008]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]
d3iwka__d3n81c___1	Viridiplantae	Metazoa	Streptophyta	Chordata	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3iwkc__d2onme___1	Viridiplantae	Metazoa	Streptophyta	Chordata	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3iwkd__d4zulh___1	Viridiplantae	Metazoa	Streptophyta	Chordata	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]; cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]		cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]
d3iwkf__d1o01b___1	Viridiplantae	Metazoa	Streptophyta	Chordata	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3iwkg__d2wmeg___1	Viridiplantae		Streptophyta	Proteobacteria	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]		glycine betaine biosynthetic process from choline [GO:0019285]			1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]
d3iwkj__d5l2ob___1	Viridiplantae	Metazoa	Streptophyta	Chordata	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; androgen binding [GO:0005497]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; GTPase activator activity [GO:0005096]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; cellular aldehyde metabolic process [GO:0006081]; ethanol oxidation [GO:0006069]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; negative regulation of cold-induced thermogenesis [GO:0120163]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cellular aldehyde metabolic process [GO:0006081]; ethanol oxidation [GO:0006069]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; negative regulation of cold-induced thermogenesis [GO:0120163]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; androgen binding [GO:0005497]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; GTPase activator activity [GO:0005096]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]
d3iwkj__d5mz8d___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	lactaldehyde dehydrogenase activity [GO:0008911]					1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	lactaldehyde dehydrogenase activity [GO:0008911]
d3iwkl__d3injd___1	Viridiplantae	Metazoa	Streptophyta	Chordata	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3iwkl__d5u0ma___1	Viridiplantae		Streptophyta	Proteobacteria	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	succinylglutamate-semialdehyde dehydrogenase activity [GO:0043824]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]		arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]			1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; nucleotide binding [GO:0000166]	succinylglutamate-semialdehyde dehydrogenase activity [GO:0043824]
d3iwvb__d2g2pb___1	Metazoa		Chordata	Proteobacteria	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]	peroxisome [GO:0005777]	periplasmic space [GO:0042597]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]
d3iwvd__d2igld1__1	Metazoa		Chordata	Proteobacteria	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	periplasmic space [GO:0042597]; hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]; purine nucleobase metabolic process [GO:0006144]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]	peroxisome [GO:0005777]	periplasmic space [GO:0042597]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]	hydroxyisourate hydrolase activity [GO:0033971]; identical protein binding [GO:0042802]
d3iwxb__d3k7rj___1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; cytosol [GO:0005829]; ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper ion binding [GO:0005507]; copper-dependent protein binding [GO:0032767]; metallochaperone activity [GO:0016530]; cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]; copper chaperone activity [GO:0016531]; cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]	ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; metallochaperone activity [GO:0016530]	copper chaperone activity [GO:0016531]
d3iwzc1_d5c8wa___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; catalytic activity [GO:0003824]; cyclic-di-GMP binding [GO:0035438]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein dimerization activity [GO:0046983]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; cofactor metabolic process [GO:0051186]; negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]	cofactor metabolic process [GO:0051186]; negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	cytosol [GO:0005829]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]	catalytic activity [GO:0003824]; cyclic-di-GMP binding [GO:0035438]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein dimerization activity [GO:0046983]	ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]
d3iwzd1_d3n4ma1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; catalytic activity [GO:0003824]; cyclic-di-GMP binding [GO:0035438]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein dimerization activity [GO:0046983]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	catalytic activity [GO:0003824]; cyclic-di-GMP binding [GO:0035438]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein dimerization activity [GO:0046983]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3iwzd1_d3od0b___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; catalytic activity [GO:0003824]; cyclic-di-GMP binding [GO:0035438]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein dimerization activity [GO:0046983]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; cyclic-di-GMP binding [GO:0035438]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein dimerization activity [GO:0046983]	ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]
d3ix9a__d3qlza1__1		Fungi	Firmicutes	Ascomycota	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d3ix9b__d3nzda___1		Metazoa	Firmicutes	Chordata	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3ixab1_d3cfda2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ixab1_d5nstc1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ixae1_d4yhnb1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ixoa__d2wl0a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ixtb1_d2a6ib3__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of syncytium formation by virus [GO:0060141]		fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of syncytium formation by virus [GO:0060141]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]	
d3ixtb2_d4k07d___1		Metazoa	Negarnaviricota	Chordata	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of syncytium formation by virus [GO:0060141]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; identical protein binding [GO:0042802]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of syncytium formation by virus [GO:0060141]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]	antigen binding [GO:0003823]; identical protein binding [GO:0042802]
d3ixtl1_d3ikca2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of syncytium formation by virus [GO:0060141]		fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of syncytium formation by virus [GO:0060141]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]	
d3ixtl2_d2oqjh2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of syncytium formation by virus [GO:0060141]		fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of syncytium formation by virus [GO:0060141]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]	
d3ixtl2_d2vita1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of syncytium formation by virus [GO:0060141]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of syncytium formation by virus [GO:0060141]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]	host cell surface receptor binding [GO:0046789]
d3j3ag__d3krwb___1		Metazoa		Chordata		G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]		adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]		G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]		G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]
d3j4ga__d3dn1a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3j6ka__d1l31a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3j9ta1_d5hkkc1__1	Fungi		Ascomycota	Firmicutes	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	ATP synthesis coupled proton transport [GO:0015986]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3j9ta4_d1kmha1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	ATP synthesis coupled proton transport [GO:0015986]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	chloroplast thylakoid membrane [GO:0009535]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3j9tb1_d3oeew1__1	Fungi	Fungi	Ascomycota	Ascomycota	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	ATP synthesis coupled proton transport [GO:0015986]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3j9tc1_d3a5cf1__1	Fungi		Ascomycota	Deinococcus-Thermus	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3j9tc4_d3a5cc4__1	Fungi		Ascomycota	Deinococcus-Thermus	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3j9td1_d1efrd2__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	ATP synthesis coupled proton transport [GO:0015986]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3j9te1_d2hldc1__1	Fungi	Fungi	Ascomycota	Ascomycota	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	ATP synthesis coupled proton transport [GO:0015986]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3j9te4_d3a5ci4__1	Fungi		Ascomycota	Deinococcus-Thermus	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3j9tf2_d3nbfc___1	Fungi		Ascomycota	Deinococcus-Thermus	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]		cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]		ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3j9tf3_d1h8hc1__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]; ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP metabolic process [GO:0046034]; cellular protein metabolic process [GO:0044267]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; vacuolar acidification [GO:0007035]	ATP synthesis coupled proton transport [GO:0015986]	cell [GO:0005623]; endomembrane system [GO:0012505]; fungal-type vacuole membrane [GO:0000329]; plasma membrane [GO:0005886]; vacuolar membrane [GO:0005774]; vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; mRNA binding [GO:0003729]; proton-transporting ATPase activity, rotational mechanism [GO:0046961]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3jb9b4_d3b82a3__1	Fungi		Ascomycota	Proteobacteria	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; post-mRNA release spliceosomal complex [GO:0071014]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]	mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387]		catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; post-mRNA release spliceosomal complex [GO:0071014]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]		mRNA binding [GO:0003729]; RNA binding [GO:0003723]	NAD+-diphthamide ADP-ribosyltransferase activity [GO:0047286]; toxin activity [GO:0090729]
d3jb9c__d1av5a___1	Fungi	Metazoa	Ascomycota	Chordata	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; post-mRNA release spliceosomal complex [GO:0071014]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; U12-type spliceosomal complex [GO:0005689]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]; U4 snRNP [GO:0005687]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	catalytic step 2 spliceosome [GO:0071013]; commitment complex [GO:0000243]; nucleus [GO:0005634]; pICln-Sm protein complex [GO:0034715]; post-mRNA release spliceosomal complex [GO:0071014]; SMN-Sm protein complex [GO:0034719]; spliceosomal complex [GO:0005681]; U12-type spliceosomal complex [GO:0005689]; U1 snRNP [GO:0005685]; U2 snRNP [GO:0005686]; U2-type prespliceosome [GO:0071004]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U4 snRNP [GO:0005687]; U5 snRNP [GO:0005682]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d3jcmj__d5szde___1	Fungi		Ascomycota	Aquificae	catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]; generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]	cytosol [GO:0005829]; RNA binding [GO:0003723]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]	regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	cytosol [GO:0005829]	mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]	RNA binding [GO:0003723]
d3jcmr__d1i8fb___1	Fungi		Ascomycota	Crenarchaeota	catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]; generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]		generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]		catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]		mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]	
d3jpza1_d3l2ec1__1	Metazoa	Metazoa	Annelida	Annelida	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]			ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3jpza2_d3l2gk2__1	Metazoa		Annelida		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]		phosphocreatine biosynthetic process [GO:0046314]				ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	
d3jpzb1_d1crkd1__1	Metazoa	Metazoa	Annelida	Chordata	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3jpzb2_d1f52e2__1	Metazoa		Annelida	Proteobacteria	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	phosphocreatine biosynthetic process [GO:0046314]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d3jq3a1_d4z9md1__1	Metazoa	Metazoa	Annelida	Chordata	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]	creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3jq3a2_d1htoo2__1	Metazoa		Annelida	Actinobacteria	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	phosphocreatine biosynthetic process [GO:0046314]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3jqwa__d1px4d3__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]; collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3jqwb__d1jz2c3__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]; collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3jqwc1_d1bglh3__1			Firmicutes		extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]; collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]		collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]		extracellular region [GO:0005576]		calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]	
d3jqxb__d1nx9b1__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]; collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]		extracellular region [GO:0005576]		calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d3jqxc1_d1xoya1__1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]; collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]	cytosol [GO:0005829]	collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]		extracellular region [GO:0005576]	cytosol [GO:0005829]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]	
d3jr5a2_d1z5ab1__1			Firmicutes	Crenarchaeota	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]			class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]
d3jr5a2_d4cisa2__1			Firmicutes	Firmicutes	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]			class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]	class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; oxidized purine nucleobase lesion DNA N-glycosylase activity [GO:0008534]; zinc ion binding [GO:0008270]
d3jr6a__d3b0kb1__1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]; lactose biosynthetic process [GO:0005989]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	lactose biosynthetic process [GO:0005989]	host cell cytoplasm [GO:0030430]	extracellular region [GO:0005576]	lysozyme activity [GO:0003796]	calcium ion binding [GO:0005509]; lactose synthase activity [GO:0004461]
d3jrmc__d5d0tg___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3jrmd__d5l5vy___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3jrmh__d4fzgj___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3js3a__d2nx3f___1			Firmicutes	Aquificae	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]		cytoplasm [GO:0005737]	3-dehydroquinate dehydratase activity [GO:0003855]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]
d3js3d__d1ewea___1		Metazoa	Firmicutes	Chordata	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]		I band [GO:0031674]; M band [GO:0031430]	3-dehydroquinate dehydratase activity [GO:0003855]	fructose-bisphosphate aldolase activity [GO:0004332]
d3js4b1_d4yipc1__1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3js4c1_d3evkc1__1			Proteobacteria	Crenarchaeota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3js4c1_d4l2ca1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3js5a1_d1jf8a___1				Firmicutes	protein tyrosine phosphatase activity [GO:0004725]	cytoplasm [GO:0005737]; arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]; response to arsenic-containing substance [GO:0046685]		response to arsenic-containing substance [GO:0046685]		cytoplasm [GO:0005737]	protein tyrosine phosphatase activity [GO:0004725]	arsenate reductase (thioredoxin) activity [GO:0030612]; metal ion binding [GO:0046872]; protein tyrosine phosphatase activity [GO:0004725]
d3js9b__d4di6f1__1			Apicomplexa	Spirochaetes	nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytosol [GO:0005829]	nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3js9c__d1xiqa___1			Apicomplexa	Apicomplexa	nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]			nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; nucleoside diphosphate kinase activity [GO:0004550]
d3jsec__d5czah___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3jsef__d4qv6z___1		Fungi		Ascomycota	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3jsen__d3oojg1__1				Proteobacteria	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	proteasome activator complex [GO:0008537]	cytosol [GO:0005829]		carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]
d3jsfb1_d2gdgb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; brain renin-angiotensin system [GO:0002035]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; drinking behavior [GO:0042756]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of axon regeneration [GO:0048680]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of glycolytic process [GO:0045821]; positive regulation of immune response [GO:0050778]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of cell population proliferation [GO:0042127]; spermatogenesis [GO:0007283]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	brain renin-angiotensin system [GO:0002035]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; drinking behavior [GO:0042756]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of axon regeneration [GO:0048680]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of glycolytic process [GO:0045821]; positive regulation of immune response [GO:0050778]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of cell population proliferation [GO:0042127]; spermatogenesis [GO:0007283]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]
d3jsfc1_d4lhoc___1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	
d3jsib1_d1ynba1__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	5'-deoxynucleotidase activity [GO:0002953]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]		3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	5'-deoxynucleotidase activity [GO:0002953]
d3jspa2_d1kcaf___1			Proteobacteria		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]; transcription, DNA-templated [GO:0006351]	virion [GO:0019012]; core promoter binding [GO:0001047]; identical protein binding [GO:0042802]; latency-replication decision [GO:0098689]; maintenance of viral latency [GO:0019044]; negative regulation of transcription by competitive promoter binding [GO:0010944]; positive regulation of viral transcription [GO:0050434]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]; transcription, DNA-templated [GO:0006351]	latency-replication decision [GO:0098689]; maintenance of viral latency [GO:0019044]; negative regulation of transcription by competitive promoter binding [GO:0010944]; positive regulation of viral transcription [GO:0050434]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	virion [GO:0019012]	DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	core promoter binding [GO:0001047]; identical protein binding [GO:0042802]
d3jt2a__d1jzha___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3jt2a__d5ue6h2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3jt2b__d2jkwb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3jtbd__d3od3a2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d3jtcb__d4l8dc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; centrosome [GO:0005813]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; signaling receptor activity [GO:0038023]; blood coagulation [GO:0007596]; negative regulation of coagulation [GO:0050819]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood coagulation [GO:0007596]; negative regulation of coagulation [GO:0050819]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; centrosome [GO:0005813]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	signaling receptor activity [GO:0038023]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3jtdb__d1a4pa___1	Metazoa	Metazoa	Mollusca	Chordata	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of plasma membrane [GO:0019897]; calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; membrane raft assembly [GO:0001765]; positive regulation of binding [GO:0051099]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; response to drug [GO:0042493]; vesicle budding from membrane [GO:0006900]		membrane raft assembly [GO:0001765]; positive regulation of binding [GO:0051099]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein heterotetramerization [GO:0051290]; protein localization to plasma membrane [GO:0072659]; response to drug [GO:0042493]; vesicle budding from membrane [GO:0006900]	myofibril [GO:0030016]; myosin complex [GO:0016459]; myosin filament [GO:0032982]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of plasma membrane [GO:0019897]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]
d3jtga__d4a5mc___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; anatomical structure morphogenesis [GO:0009653]; blastocyst development [GO:0001824]; cell differentiation [GO:0030154]; epithelial cell differentiation [GO:0030855]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; mammary gland involution [GO:0060056]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; transcription by RNA polymerase II [GO:0006366]	DNA binding [GO:0003677]	anatomical structure morphogenesis [GO:0009653]; blastocyst development [GO:0001824]; cell differentiation [GO:0030154]; epithelial cell differentiation [GO:0030855]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; mammary gland involution [GO:0060056]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]		cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]	DNA binding [GO:0003677]
d3jtka2_d2z3oa___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]; cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	cytoplasm [GO:0005737]; leucyltransferase activity [GO:0008914]; transferase activity, transferring amino-acyl groups [GO:0016755]; protein catabolic process [GO:0030163]	cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	protein catabolic process [GO:0030163]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]	leucyltransferase activity [GO:0008914]; transferase activity, transferring amino-acyl groups [GO:0016755]
d3jtub__d3kerc___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine receptor binding [GO:0005126]; D-dopachrome decarboxylase activity [GO:0033981]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; melanin biosynthetic process [GO:0042438]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of tumor necrosis factor production [GO:0032760]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	melanin biosynthetic process [GO:0042438]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of tumor necrosis factor production [GO:0032760]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	cytokine receptor binding [GO:0005126]; D-dopachrome decarboxylase activity [GO:0033981]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]
d3ju4a2_d3ekaa2__1				Firmicutes	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	hyalurononglucosaminidase activity [GO:0004415]; capsule polysaccharide biosynthetic process [GO:0045227]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	capsule polysaccharide biosynthetic process [GO:0045227]	virus tail, fiber [GO:0098024]		endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]	hyalurononglucosaminidase activity [GO:0004415]
d3ju9a__d1lu1a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]					mannose binding [GO:0005537]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]
d3jutc__d2irta___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; interleukin-1 type I receptor antagonist activity [GO:0045352]; interleukin-1 type II receptor antagonist activity [GO:0045353]; interleukin-1, type I receptor binding [GO:0005150]; interleukin-1, type II receptor binding [GO:0005151]; acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; interleukin-1-mediated signaling pathway [GO:0070498]; lipid metabolic process [GO:0006629]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; response to glucocorticoid [GO:0051384]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; interleukin-1-mediated signaling pathway [GO:0070498]; lipid metabolic process [GO:0006629]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; response to glucocorticoid [GO:0051384]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-1, type II receptor binding [GO:0005151]; interleukin-1, type I receptor binding [GO:0005150]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; interleukin-1 type II receptor antagonist activity [GO:0045353]; interleukin-1 type I receptor antagonist activity [GO:0045352]
d3juya2_d1rivl1__1												
d3juya2_d3okea1__1												
d3juyb1_d1bfog1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3juyb1_d1ty5l3__1												
d3juyb2_d4w4ob1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3juyc2_d4n0fk2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3juyd1_d1nl0h1__1		Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]		blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]		collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]
d3juye2_d5u2ve1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3juyf2_d4yjzl2__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d3jv4a__d1s9kc1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3jv4c__d3jv6f___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d3jv4d__d1d7fa1__1	Metazoa		Chordata	Firmicutes	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	carbohydrate metabolic process [GO:0005975]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	extracellular region [GO:0005576]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3jv4f__d4yefc___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; fatty acid biosynthetic process [GO:0006633]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; regulation of catalytic activity [GO:0050790]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	fatty acid biosynthetic process [GO:0006633]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; regulation of catalytic activity [GO:0050790]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]
d3jv6a__d1ogpb1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]
d3jv6c__d1le9b1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3jv6c__d5tb5b___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]; actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	actin cytoskeleton organization [GO:0030036]; cytokine-mediated signaling pathway [GO:0019221]; endocrine signaling [GO:0038002]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; female pregnancy [GO:0007565]; forebrain astrocyte development [GO:0021897]; homeostasis of number of cells within a tissue [GO:0048873]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Rac protein signal transduction [GO:0035022]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to glucocorticoid [GO:0051384]; response to isolation stress [GO:0035900]; response to mineralocorticoid [GO:0051385]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; striated muscle cell differentiation [GO:0051146]; visual learning [GO:0008542]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	GDP binding [GO:0019003]; GMP binding [GO:0019002]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; protein-containing complex binding [GO:0044877]
d3jv6d__d1gjib1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; apoptotic DNA fragmentation [GO:0006309]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	apoptotic DNA fragmentation [GO:0006309]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d3jv6d__d3n43f2__1	Metazoa		Chordata		centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	host cell cytoplasm [GO:0030430]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	host cell cytoplasm [GO:0030430]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; virion membrane [GO:0055036]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3jvgc__d5jo5f1__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]		amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]		cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]		protein homodimerization activity [GO:0042803]	
d3jvwb__d4y5ma___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3jw0a__d5ulfc1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3jw0x__d2zzpb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endomembrane system [GO:0012505]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; neuronal cell body [GO:0043025]; microtubule binding [GO:0008017]; protein domain specific binding [GO:0019904]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]; positive regulation of protein binding [GO:0032092]	cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]; positive regulation of protein binding [GO:0032092]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endomembrane system [GO:0012505]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; neuronal cell body [GO:0043025]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	microtubule binding [GO:0008017]; protein domain specific binding [GO:0019904]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]
d3jw2b__d1bvgb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3jw3a1_d4elfa1__1			Firmicutes	Firmicutes	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d3jw3a1_d5ccca___1			Firmicutes	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d3jw5a1_d1cd2a___1		Fungi	Firmicutes	Ascomycota	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3jwca1_d1d1gb___1			Firmicutes	Thermotogae	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3jwdc1_d1namh1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3jwdd1_d2edwa1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]
d3jwdl2_d1ymhc1__1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	pathogenesis [GO:0009405]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell wall [GO:0005618]; extracellular region [GO:0005576]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]
d3jwdo1_d3fruf___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	
d3jwfa1_d4ky8c1__1			Firmicutes		dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	
d3jwka1_d5ht5a___1		Metazoa	Firmicutes	Chordata	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3jwkb1_d1hfra___1		Metazoa	Firmicutes	Chordata	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3jwmb1_d4km2a___1			Firmicutes	Actinobacteria	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]
d3jwne__d4ca4b___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]	pilus [GO:0009289]	pilus [GO:0009289]		
d3jwnf__d4avkb___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d3jwnh2_d1klfh1__1			Proteobacteria	Proteobacteria	pilus [GO:0009289]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d3jwnn2_d5wtaa1__1			Proteobacteria	Firmicutes	pilus [GO:0009289]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	pilus [GO:0009289]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]		
d3jwqc1_d2hd1a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytosol [GO:0005829]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3jxsc__d1cx1a1__1			Bacteroidetes	Actinobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]
d3jxsc__d1jz3c3__1			Bacteroidetes	Proteobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3jxya1_d1h19a1__1		Metazoa	Firmicutes	Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]		aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3jyra__d1lb9a___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3jz4a__d4fqfb___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; NADP binding [GO:0050661]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; gamma-aminobutyric acid catabolic process [GO:0009450]; nitrogen compound metabolic process [GO:0006807]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	gamma-aminobutyric acid catabolic process [GO:0009450]; nitrogen compound metabolic process [GO:0006807]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytoplasm [GO:0005737]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	NADP binding [GO:0050661]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3jz4b__d5kj5d___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; NADP binding [GO:0050661]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; gamma-aminobutyric acid catabolic process [GO:0009450]; nitrogen compound metabolic process [GO:0006807]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	gamma-aminobutyric acid catabolic process [GO:0009450]; nitrogen compound metabolic process [GO:0006807]		cytoplasm [GO:0005737]		NADP binding [GO:0050661]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3jz4d__d4zulf___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; NADP binding [GO:0050661]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]; gamma-aminobutyric acid catabolic process [GO:0009450]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]; cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	gamma-aminobutyric acid catabolic process [GO:0009450]; nitrogen compound metabolic process [GO:0006807]	cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	NADP binding [GO:0050661]; succinate-semialdehyde dehydrogenase (NAD+) activity [GO:0004777]; succinate-semialdehyde dehydrogenase [NAD(P)+] activity [GO:0009013]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]
d3jzfa1_d4eg0b1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d3jzfa2_d1kjja1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d3jzia2_d2yzma2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d3jzqb__d3vbgb___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; 5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]	5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d3k01a1_d4o3ca1__1		Metazoa	Actinobacteria	Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3k02a__d1ziua1__1			Actinobacteria	Proteobacteria		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3k0ja__d2leba___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	mRNA 3'-end processing [GO:0031124]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]
d3k1ia__d1orya___1			Proteobacteria	Aquificae	cytosol [GO:0005829]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]	bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]	bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]	bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]	cytosol [GO:0005829]			
d3k1kd1_d5d72n2__1	Metazoa	Metazoa	Cnidaria	Chordata	bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]	cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]		cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]
d3k1xa__d4depa___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]
d3k1xf__d1irax___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; interleukin-1, type I, activating receptor activity [GO:0004909]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-1-mediated signaling pathway [GO:2000661]; positive regulation of neutrophil extravasation [GO:2000391]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	interleukin-1, type I, activating receptor activity [GO:0004909]; interleukin-1 binding [GO:0019966]; interleukin-1 receptor activity [GO:0004908]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; transmembrane signaling receptor activity [GO:0004888]
d3k2ha1_d2c2sb___1		Metazoa	Apicomplexa	Chordata	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3k2ha1_d4x5ga___1			Apicomplexa	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d3k2hb1_d3nxra___1		Metazoa	Apicomplexa	Chordata	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3k2hb2_d1tdub___1			Apicomplexa	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; regulation of translation [GO:0006417]; response to radiation [GO:0009314]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; thymidylate synthase activity [GO:0004799]
d3k2hb2_d4iqqb___1		Metazoa	Apicomplexa	Nematoda (roundworms)	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]			dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d3k2ja1_d5pgca1__1	Metazoa	Metazoa	Chordata	Chordata	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]	nucleus [GO:0005634]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d3k2md__d5ecjf___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714]; epithelial cell differentiation [GO:0030855]; intestinal epithelial cell differentiation [GO:0060575]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of neuron projection development [GO:0010976]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	epithelial cell differentiation [GO:0030855]; intestinal epithelial cell differentiation [GO:0060575]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of neuron projection development [GO:0010976]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]	nucleus [GO:0005634]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]	DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; transcription corepressor activity [GO:0003714]
d3k2ra__d5apda___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3k2ul1_d4z78d2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	proteolysis [GO:0006508]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; rough endoplasmic reticulum [GO:0005791]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3k2wb1_d4kwfg___1		Metazoa	Proteobacteria	Chordata	betaine-aldehyde dehydrogenase activity [GO:0008802]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	betaine-aldehyde dehydrogenase activity [GO:0008802]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3k2we1_d1of7b___1			Proteobacteria		betaine-aldehyde dehydrogenase activity [GO:0008802]						betaine-aldehyde dehydrogenase activity [GO:0008802]	
d3k2we1_d5eebe___1			Proteobacteria	Crenarchaeota	betaine-aldehyde dehydrogenase activity [GO:0008802]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]					betaine-aldehyde dehydrogenase activity [GO:0008802]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3k36b__d3ticd___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3k37a__d1v0zb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3k38a__d5l14a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3k38b__d4qn5a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3k38c__d1v0eb1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	virus tail, fiber [GO:0098024]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]
d3k38c__d2agsa2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d3k38e__d4gdia___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3k38f__d5huga___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3k38i__d7nn9a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3k38k__d1mz5a2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]	metabolic process [GO:0008152]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d3k38l__d3ju4a1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	virus tail, fiber [GO:0098024]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]
d3k38n__d4fvkb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3k38p__d4gezd___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3k39c__d1ncbn___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3k39d__d2ht8a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3k39g__d3cyeb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3k39h__d1v0fc1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	virus tail, fiber [GO:0098024]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]
d3k39l__d1euua3__1			Negarnaviricota	Actinobacteria	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]	metabolic process [GO:0008152]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d3k39p__d1s0ia2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]	pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-sialidase activity [GO:0004308]
d3k3ab__d3cl2c___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3k3ae__d3gvja1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	virus tail, fiber [GO:0098024]; endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; disruption of host cell glycocalyx during viral entry [GO:0098996]; entry into host via enzymatic degradation of host anatomical structure [GO:0085027]; metabolic process [GO:0008152]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	virus tail, fiber [GO:0098024]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	endo-alpha-(2,8)-sialidase activity [GO:0016996]; identical protein binding [GO:0042802]
d3k3af__d2ah2a2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]	pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-sialidase activity [GO:0004308]
d3k3ai__d3ti8b___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3k3aj__d1v3da___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-sialidase activity [GO:0004308]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d3k3ak__d3k36a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3k3ea__d3ly2b1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d3k3eb__d5tzhc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d3k3la__d1gt5b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	extracellular region [GO:0005576]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	small molecule binding [GO:0036094]
d3k3lc__d4grjb___1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	vasodilation [GO:0042311]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	extracellular region [GO:0005576]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d3k3lc__d4qztd___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytosol [GO:0005829]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3k3ua__d1sdka___1	Metazoa	Metazoa	Annelida	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3k3ua__d5d1vb___1	Metazoa		Annelida	Chloroflexi	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]		cell [GO:0005623]; cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; thioredoxin peroxidase activity [GO:0008379]
d3k45a__d1rb3a___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d3k46b1_d2j22a___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]		beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	metal ion binding [GO:0046872]
d3k46b2_d1yq2a1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]	beta-galactosidase complex [GO:0009341]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3k46b2_d3dypc4__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	lactose catabolic process [GO:0005990]	cytosol [GO:0005829]	beta-galactosidase complex [GO:0009341]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3k47a__d4elfd1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d3k48b__d4qqha___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; tumor necrosis factor receptor binding [GO:0005164]; immunoglobulin mediated immune response [GO:0016064]; immunoglobulin production in mucosal tissue [GO:0002426]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of germinal center formation [GO:0002636]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of immune response [GO:0050776]	collagen trimer [GO:0005581]; extracellular region [GO:0005576]; identical protein binding [GO:0042802]; regulation of synapse organization [GO:0050807]	immunoglobulin mediated immune response [GO:0016064]; immunoglobulin production in mucosal tissue [GO:0002426]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of germinal center formation [GO:0002636]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of immune response [GO:0050776]	regulation of synapse organization [GO:0050807]	cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]	collagen trimer [GO:0005581]; extracellular region [GO:0005576]	cytokine activity [GO:0005125]; tumor necrosis factor receptor binding [GO:0005164]	identical protein binding [GO:0042802]
d3k48b__d5mu8e___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; tumor necrosis factor receptor binding [GO:0005164]; immunoglobulin mediated immune response [GO:0016064]; immunoglobulin production in mucosal tissue [GO:0002426]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of germinal center formation [GO:0002636]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	immunoglobulin mediated immune response [GO:0016064]; immunoglobulin production in mucosal tissue [GO:0002426]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of germinal center formation [GO:0002636]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of immune response [GO:0050776]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	cytokine activity [GO:0005125]; tumor necrosis factor receptor binding [GO:0005164]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d3k48d__d5kc6b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; tumor necrosis factor receptor binding [GO:0005164]; immunoglobulin mediated immune response [GO:0016064]; immunoglobulin production in mucosal tissue [GO:0002426]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of germinal center formation [GO:0002636]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of immune response [GO:0050776]	cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic membrane [GO:0045211]; synaptic cleft [GO:0043083]; protein homodimerization activity [GO:0042803]; cerebellar granule cell differentiation [GO:0021707]; chemical synaptic transmission [GO:0007268]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of excitatory postsynaptic potential [GO:0090394]; nervous system development [GO:0007399]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; protein secretion [GO:0009306]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]	immunoglobulin mediated immune response [GO:0016064]; immunoglobulin production in mucosal tissue [GO:0002426]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of germinal center formation [GO:0002636]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of immune response [GO:0050776]	cerebellar granule cell differentiation [GO:0021707]; chemical synaptic transmission [GO:0007268]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of excitatory postsynaptic potential [GO:0090394]; nervous system development [GO:0007399]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; protein secretion [GO:0009306]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]	cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]	cell junction [GO:0030054]; collagen-containing extracellular matrix [GO:0062023]; glutamatergic synapse [GO:0098978]; parallel fiber to Purkinje cell synapse [GO:0098688]; postsynaptic membrane [GO:0045211]; synaptic cleft [GO:0043083]	cytokine activity [GO:0005125]; tumor necrosis factor receptor binding [GO:0005164]	protein homodimerization activity [GO:0042803]
d3k4aa2_d1jyzn1__1			Proteobacteria		cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]		glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]		cytosol [GO:0005829]		beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	
d3k4db1_d1w8wb___1		Fungi	Proteobacteria	Chytridiomycota	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]		glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]		cytosol [GO:0005829]		beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	
d3k4qa__d1xq9b___1	Fungi		Ascomycota	Apicomplexa	extracellular region [GO:0005576]; 3-phytase activity [GO:0016158]	cytosol [GO:0005829]; phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]	extracellular region [GO:0005576]	cytosol [GO:0005829]	3-phytase activity [GO:0016158]	phosphoglycerate mutase activity [GO:0004619]
d3k4sa1_d2oupa1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3k4vb__d3vswa___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d3k4vc__d2igxa___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3k4xa1_d3vkxa1__1	Fungi	Metazoa	Ascomycota	Chordata	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	nucleus [GO:0005634]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d3k4xa1_d4n94b1__1	Fungi		Ascomycota	Proteobacteria	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	nucleus [GO:0005634]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3k4xa2_d1mmib1__1	Fungi		Ascomycota	Proteobacteria	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	nucleus [GO:0005634]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3k4xa3_d3qsba3__1	Fungi		Ascomycota	Proteobacteria	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	nucleus [GO:0005634]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3k5ra2_d3qrba1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d3k5rb2_d3ff8a1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3k5sa1_d3ff8b1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3k5sa2_d3q2nb2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d3k5sb1_d5jymc2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3k67b__d5szvb___1			Euryarchaeota	Proteobacteria	fatty acid synthase complex [GO:0005835]; fatty acid synthase activity [GO:0004312]; fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114]	thiolester hydrolase activity [GO:0016790]	fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114]		fatty acid synthase complex [GO:0005835]		fatty acid synthase activity [GO:0004312]	thiolester hydrolase activity [GO:0016790]
d3k6fa1_d3lnia2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d3k6fb1_d4zmwb2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3k6ia1_d3k6fa1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]
d3k6ia1_d5n30a1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; contractile ring [GO:0070938]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystroglycan complex [GO:0016011]; dystrophin-associated glycoprotein complex [GO:0016010]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; membrane [GO:0016020]; membrane raft [GO:0045121]; node of Ranvier [GO:0033268]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]; synapse [GO:0045202]; actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; calcium ion binding [GO:0005509]; dystroglycan binding [GO:0002162]; laminin binding [GO:0043236]; laminin-1 binding [GO:0043237]; SH2 domain binding [GO:0042169]; structural constituent of muscle [GO:0008307]; tubulin binding [GO:0015631]; vinculin binding [GO:0017166]; aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; Schwann cell development [GO:0014044]; skeletal muscle tissue regeneration [GO:0043403]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	aging [GO:0007568]; angiogenesis involved in wound healing [GO:0060055]; axon regeneration [GO:0031103]; basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; cellular response to cholesterol [GO:0071397]; cellular response to mechanical stimulus [GO:0071260]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein kinase activity [GO:0045860]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of synapse organization [GO:0050807]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to peptide hormone [GO:0043434]; retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942]; Schwann cell development [GO:0014044]; skeletal muscle tissue regeneration [GO:0043403]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]	basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; contractile ring [GO:0070938]; costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dystroglycan complex [GO:0016011]; dystrophin-associated glycoprotein complex [GO:0016010]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; membrane [GO:0016020]; membrane raft [GO:0045121]; node of Ranvier [GO:0033268]; nuclear periphery [GO:0034399]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; sarcolemma [GO:0042383]; synapse [GO:0045202]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; alpha-actinin binding [GO:0051393]; calcium ion binding [GO:0005509]; dystroglycan binding [GO:0002162]; laminin-1 binding [GO:0043237]; laminin binding [GO:0043236]; SH2 domain binding [GO:0042169]; structural constituent of muscle [GO:0008307]; tubulin binding [GO:0015631]; vinculin binding [GO:0017166]
d3k6ka__d3aina___1				Crenarchaeota	hydrolase activity [GO:0016787]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]					hydrolase activity [GO:0016787]	identical protein binding [GO:0042802]; methyl indole-3-acetate esterase activity [GO:0080030]
d3k6ka__d3habb2__1		Metazoa		Chordata	hydrolase activity [GO:0016787]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	hydrolase activity [GO:0016787]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3k6mb1_d4eubb2__1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]; acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	acetate catabolic process [GO:0045733]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate metabolic process, methylcitrate cycle [GO:0019679]; succinyl-CoA catabolic process [GO:1901289]	mitochondrion [GO:0005739]		3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	acetate CoA-transferase activity [GO:0008775]; acetyl-CoA hydrolase activity [GO:0003986]; transferase activity [GO:0016740]
d3k6mc2_d3dlxb1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; adipose tissue development [GO:0060612]; brain development [GO:0007420]; cellular ketone body metabolic process [GO:0046950]; heart development [GO:0007507]; ketone body catabolic process [GO:0046952]; ketone catabolic process [GO:0042182]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	adipose tissue development [GO:0060612]; brain development [GO:0007420]; cellular ketone body metabolic process [GO:0046950]; heart development [GO:0007507]; ketone body catabolic process [GO:0046952]; ketone catabolic process [GO:0042182]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; response to activity [GO:0014823]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]	mitochondrion [GO:0005739]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]
d3k6md2_d1ne7e___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; single fertilization [GO:0007338]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; single fertilization [GO:0007338]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]
d3k6va__d2wx9a1__1			Euryarchaeota	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; tungstate binding [GO:1901359]	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]		carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]	tungstate binding [GO:1901359]	
d3k6wa__d3c34a___1		Metazoa	Euryarchaeota	Chordata	outer membrane-bounded periplasmic space [GO:0030288]; tungstate binding [GO:1901359]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	tungstate binding [GO:1901359]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d3k74b__d2rcjr2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	
d3k77e__d5dn2d___1	Metazoa	Metazoa	Chordata	Chordata	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]
d3k7fa__d1o9pa___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]	amidase activity [GO:0004040]	fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]		acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]	amidase activity [GO:0004040]
d3k7hb__d1r44b___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; patched binding [GO:0005113]; peptidase activity [GO:0008233]; bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye photoreceptor cell fate commitment [GO:0060220]; cartilage development [GO:0051216]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; cell-cell signaling [GO:0007267]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte proliferation [GO:0035988]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint development [GO:0072498]; epithelial cell morphogenesis [GO:0003382]; epithelial cell-cell adhesion [GO:0090136]; head morphogenesis [GO:0060323]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; intein-mediated protein splicing [GO:0016539]; liver regeneration [GO:0097421]; maternal process involved in female pregnancy [GO:0060135]; multicellular organism growth [GO:0035264]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of eye pigmentation [GO:0048074]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell differentiation in thymus [GO:0033085]; neuron development [GO:0048666]; osteoblast differentiation [GO:0001649]; pancreas development [GO:0031016]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; retinal pigment epithelium development [GO:0003406]; skeletal system development [GO:0001501]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; somite development [GO:0061053]; vitelline membrane formation [GO:0030704]	dipeptidase activity [GO:0016805]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; cell wall organization [GO:0071555]; response to antibiotic [GO:0046677]	bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye photoreceptor cell fate commitment [GO:0060220]; cartilage development [GO:0051216]; cell-cell signaling [GO:0007267]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte proliferation [GO:0035988]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint development [GO:0072498]; epithelial cell-cell adhesion [GO:0090136]; epithelial cell morphogenesis [GO:0003382]; head morphogenesis [GO:0060323]; heart looping [GO:0001947]; intein-mediated protein splicing [GO:0016539]; in utero embryonic development [GO:0001701]; liver regeneration [GO:0097421]; maternal process involved in female pregnancy [GO:0060135]; multicellular organism growth [GO:0035264]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of eye pigmentation [GO:0048074]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell differentiation in thymus [GO:0033085]; neuron development [GO:0048666]; osteoblast differentiation [GO:0001649]; pancreas development [GO:0031016]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; retinal pigment epithelium development [GO:0003406]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; smooth muscle tissue development [GO:0048745]; somite development [GO:0061053]; vitelline membrane formation [GO:0030704]	cell wall organization [GO:0071555]; response to antibiotic [GO:0046677]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; patched binding [GO:0005113]; peptidase activity [GO:0008233]	dipeptidase activity [GO:0016805]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]
d3k7ib__d2vo9a1__1	Metazoa		Chordata		extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; patched binding [GO:0005113]; peptidase activity [GO:0008233]; bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye photoreceptor cell fate commitment [GO:0060220]; cartilage development [GO:0051216]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; cell-cell signaling [GO:0007267]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte proliferation [GO:0035988]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint development [GO:0072498]; epithelial cell morphogenesis [GO:0003382]; epithelial cell-cell adhesion [GO:0090136]; head morphogenesis [GO:0060323]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; intein-mediated protein splicing [GO:0016539]; liver regeneration [GO:0097421]; maternal process involved in female pregnancy [GO:0060135]; multicellular organism growth [GO:0035264]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of eye pigmentation [GO:0048074]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell differentiation in thymus [GO:0033085]; neuron development [GO:0048666]; osteoblast differentiation [GO:0001649]; pancreas development [GO:0031016]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; retinal pigment epithelium development [GO:0003406]; skeletal system development [GO:0001501]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; somite development [GO:0061053]; vitelline membrane formation [GO:0030704]	extracellular region [GO:0005576]; peptidase activity [GO:0008233]; cell wall organization [GO:0071555]	bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye photoreceptor cell fate commitment [GO:0060220]; cartilage development [GO:0051216]; cell-cell signaling [GO:0007267]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte proliferation [GO:0035988]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint development [GO:0072498]; epithelial cell-cell adhesion [GO:0090136]; epithelial cell morphogenesis [GO:0003382]; head morphogenesis [GO:0060323]; heart looping [GO:0001947]; intein-mediated protein splicing [GO:0016539]; in utero embryonic development [GO:0001701]; liver regeneration [GO:0097421]; maternal process involved in female pregnancy [GO:0060135]; multicellular organism growth [GO:0035264]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of eye pigmentation [GO:0048074]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell differentiation in thymus [GO:0033085]; neuron development [GO:0048666]; osteoblast differentiation [GO:0001649]; pancreas development [GO:0031016]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; retinal pigment epithelium development [GO:0003406]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; smooth muscle tissue development [GO:0048745]; somite development [GO:0061053]; vitelline membrane formation [GO:0030704]	cell wall organization [GO:0071555]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; patched binding [GO:0005113]; peptidase activity [GO:0008233]	peptidase activity [GO:0008233]
d3k7oa__d2besc___1				Actinobacteria	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]	ribose-5-phosphate isomerase activity [GO:0004751]
d3k7oa__d4em8a1__1				Proteobacteria	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			identical protein binding [GO:0042802]; isomerase activity [GO:0016853]	ribose-5-phosphate isomerase activity [GO:0004751]
d3k7ob__d3he8a___1				Firmicutes	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			identical protein binding [GO:0042802]; isomerase activity [GO:0016853]	ribose-5-phosphate isomerase activity [GO:0004751]
d3k7pb__d2vvod___1				Actinobacteria	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]	ribose-5-phosphate isomerase activity [GO:0004751]
d3k7ra__d1s6ua1__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; copper chaperone activity [GO:0016531]; cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]; antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cell [GO:0005623]; cytosol [GO:0005829]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	copper chaperone activity [GO:0016531]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]
d3k7rb__d1jwwa___1	Fungi		Ascomycota	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; copper chaperone activity [GO:0016531]; cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; identical protein binding [GO:0042802]	cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytosol [GO:0005829]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	copper chaperone activity [GO:0016531]	ATP binding [GO:0005524]; copper ion binding [GO:0005507]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; identical protein binding [GO:0042802]
d3k7rb__d1y3ka1__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; copper chaperone activity [GO:0016531]; cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]; antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cell [GO:0005623]; cytosol [GO:0005829]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	copper chaperone activity [GO:0016531]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]
d3k7rd__d2roga___1	Fungi		Ascomycota	Deinococcus-Thermus	cell [GO:0005623]; cytosol [GO:0005829]; copper chaperone activity [GO:0016531]; cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	metal ion binding [GO:0046872]; metal ion transport [GO:0030001]	cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	metal ion transport [GO:0030001]	cell [GO:0005623]; cytosol [GO:0005829]		copper chaperone activity [GO:0016531]	metal ion binding [GO:0046872]
d3k7re__d2ldia___1	Fungi		Ascomycota	Cyanobacteria	cell [GO:0005623]; cytosol [GO:0005829]; copper chaperone activity [GO:0016531]; cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; cadmium ion transmembrane transporter activity [GO:0015086]; metal ion binding [GO:0046872]; zinc ion transmembrane transporter activity [GO:0005385]; zinc transmembrane transporter activity, phosphorylative mechanism [GO:0016463]	cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytosol [GO:0005829]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	copper chaperone activity [GO:0016531]	ATP binding [GO:0005524]; cadmium ion transmembrane transporter activity [GO:0015086]; metal ion binding [GO:0046872]; zinc ion transmembrane transporter activity [GO:0005385]; zinc transmembrane transporter activity, phosphorylative mechanism [GO:0016463]
d3k7rg__d1yjta1__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; copper chaperone activity [GO:0016531]; cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; copper-dependent protein binding [GO:0032767]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]; antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	antimicrobial humoral response [GO:0019730]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; cellular response to amino acid stimulus [GO:0071230]; cellular response to antibiotic [GO:0071236]; cellular response to cadmium ion [GO:0071276]; cellular response to cobalt ion [GO:0071279]; cellular response to copper ion [GO:0071280]; cellular response to hypoxia [GO:0071456]; cellular response to iron ion [GO:0071281]; cellular response to lead ion [GO:0071284]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; liver development [GO:0001889]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of iron ion transmembrane transport [GO:0034760]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell size [GO:0045793]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of response to wounding [GO:1903036]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; pyramidal neuron development [GO:0021860]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to manganese ion [GO:0010042]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	cell [GO:0005623]; cytosol [GO:0005829]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	copper chaperone activity [GO:0016531]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; copper ion transmembrane transporter activity [GO:0005375]; copper transmembrane transporter activity, phosphorylative mechanism [GO:0043682]; cuprous ion binding [GO:1903136]; Rac GTPase binding [GO:0048365]; superoxide dismutase copper chaperone activity [GO:0016532]
d3k7sa__d2vvpe___1				Actinobacteria	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]	ribose-5-phosphate isomerase activity [GO:0004751]
d3k7sb__d2vvqd___1				Actinobacteria	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]	ribose-5-phosphate isomerase activity [GO:0004751]
d3k7sc__d2vvoe___1				Actinobacteria	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]	ribose-5-phosphate isomerase activity [GO:0004751]
d3k7ua1_d1d9kg1__1		Metazoa		Chordata	kinetoplast [GO:0020023]; mitochondrial mRNA editing complex [GO:0031019]; nucleus [GO:0005634]; endonuclease activity [GO:0004519]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; RNA modification [GO:0009451]	T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]	RNA modification [GO:0009451]	adaptive immune response [GO:0002250]	kinetoplast [GO:0020023]; mitochondrial mRNA editing complex [GO:0031019]; nucleus [GO:0005634]	T cell receptor complex [GO:0042101]	endonuclease activity [GO:0004519]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]	
d3k7ua1_d1eo8l1__1				Negarnaviricota	kinetoplast [GO:0020023]; mitochondrial mRNA editing complex [GO:0031019]; nucleus [GO:0005634]; endonuclease activity [GO:0004519]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; RNA modification [GO:0009451]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	RNA modification [GO:0009451]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	kinetoplast [GO:0020023]; mitochondrial mRNA editing complex [GO:0031019]; nucleus [GO:0005634]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	endonuclease activity [GO:0004519]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]	host cell surface receptor binding [GO:0046789]
d3k7wc__d2ahdd___1	Metazoa		Chordata	Euryarchaeota	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]		chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]		GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3k80b1_d3wfbl1__1				Proteobacteria	kinetoplast [GO:0020023]; mitochondrial mRNA editing complex [GO:0031019]; nucleus [GO:0005634]; endonuclease activity [GO:0004519]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; RNA modification [GO:0009451]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]; aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	RNA modification [GO:0009451]	aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	kinetoplast [GO:0020023]; mitochondrial mRNA editing complex [GO:0031019]; nucleus [GO:0005634]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	endonuclease activity [GO:0004519]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]	cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]
d3k86a__d1vl7a___1			Proteobacteria	Cyanobacteria	FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [GO:0016646]; protein homodimerization activity [GO:0042803]; aromatic compound catabolic process [GO:0019439]; oxidation-reduction process [GO:0055114]	cofactor binding [GO:0048037]	aromatic compound catabolic process [GO:0019439]; oxidation-reduction process [GO:0055114]				FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [GO:0016646]; protein homodimerization activity [GO:0042803]	cofactor binding [GO:0048037]
d3k8ba__d1g9vb___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3k8ca__d2vvoa___1				Actinobacteria	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]	ribose-5-phosphate isomerase activity [GO:0004751]
d3k8cb__d1usld___1				Actinobacteria	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]	ribose-5-phosphate isomerase activity [GO:0004751]
d3k8cb__d2vvrf___1				Proteobacteria	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]; D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]	D-allose catabolic process [GO:0019316]; pentose-phosphate shunt [GO:0006098]			identical protein binding [GO:0042802]; isomerase activity [GO:0016853]	allose 6-phosphate isomerase activity [GO:0008786]; ribose-5-phosphate isomerase activity [GO:0004751]
d3k8dc__d2xw5a___1			Proteobacteria		cytosol [GO:0005829]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; magnesium ion binding [GO:0000287]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]		CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]		cytosol [GO:0005829]		3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; magnesium ion binding [GO:0000287]	
d3k8na__d4fiwa___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]; oxidation-reduction process [GO:0055114]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of plasma membrane [GO:0031237]; outer membrane-bounded periplasmic space [GO:0030288]	cell [GO:0005623]	disulfide oxidoreductase activity [GO:0015036]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d3k8oe__d4wkbb1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]		drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d3k8os__d1u1db___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	cytosol [GO:0005829]	drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]
d3k8oy__d4ecef___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]	drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]
d3k8zb1_d1nqth2__1		Metazoa	Firmicutes	Chordata	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase (NAD+) activity [GO:0004352]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d3k8zc1_d3aogi1__1			Firmicutes	Deinococcus-Thermus	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	cellular amino acid metabolic process [GO:0006520]			glutamate dehydrogenase (NAD+) activity [GO:0004352]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d3k8zc2_d3czma1__1			Firmicutes	Apicomplexa	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]			glutamate dehydrogenase (NAD+) activity [GO:0004352]	L-lactate dehydrogenase activity [GO:0004459]
d3k8zd1_d1hwxc3__1			Firmicutes		glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]		cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]				glutamate dehydrogenase (NAD+) activity [GO:0004352]	
d3k8ze1_d1gtmc2__1			Firmicutes	Euryarchaeota	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	cellular amino acid metabolic process [GO:0006520]		cytoplasm [GO:0005737]	glutamate dehydrogenase (NAD+) activity [GO:0004352]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d3k8zf1_d3tozd1__1			Firmicutes	Firmicutes	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	glutamate dehydrogenase (NAD+) activity [GO:0004352]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d3k92b1_d1hwyb2__1		Metazoa	Firmicutes	Chordata	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase (NAD+) activity [GO:0004352]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d3k92b1_d3aogf1__1			Firmicutes	Deinococcus-Thermus	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	cellular amino acid metabolic process [GO:0006520]			glutamate dehydrogenase (NAD+) activity [GO:0004352]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d3k92d1_d1hwyc2__1		Metazoa	Firmicutes	Chordata	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase (NAD+) activity [GO:0004352]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d3k96b1_d2x86d___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycerol-3-phosphate dehydrogenase [NAD(P)+] activity [GO:0047952]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophospholipid biosynthetic process [GO:0046474]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophospholipid biosynthetic process [GO:0046474]	ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]		glycerol-3-phosphate dehydrogenase [NAD(P)+] activity [GO:0047952]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]	ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]
d3k99a1_d2hkja3__1	Metazoa		Chordata	Crenarchaeota	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]
d3k99b1_d2xx2d___1	Metazoa	Fungi	Chordata	Ascomycota	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]
d3k99d1_d3qtfa___1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3k9sa1_d4yeta1__1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3k9sc2_d4l2dd2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3k9sd2_d1kkcx2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	IgE binding [GO:0019863]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3k9sd2_d3ak2b2__1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3k9ua__d4f0ya___1			Euryarchaeota	Proteobacteria	diamine N-acetyltransferase activity [GO:0004145]; negative regulation of sporulation [GO:0043939]	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]; response to antibiotic [GO:0046677]	negative regulation of sporulation [GO:0043939]	response to antibiotic [GO:0046677]			diamine N-acetyltransferase activity [GO:0004145]	aminoglycoside 6'-N-acetyltransferase activity [GO:0047663]
d3k9va__d4wqja___1	Metazoa		Chordata	Crenarchaeota	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity [GO:0030342]; 25-hydroxycholecalciferol-24-hydroxylase activity [GO:0008403]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; osteoblast differentiation [GO:0001649]; response to vitamin D [GO:0033280]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]	osteoblast differentiation [GO:0001649]; response to vitamin D [GO:0033280]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359]		mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity [GO:0030342]; 25-hydroxycholecalciferol-24-hydroxylase activity [GO:0008403]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]
d3k9wa1_d2hgza1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	coenzyme A biosynthetic process [GO:0015937]	tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; tyrosine-tRNA ligase activity [GO:0004831]
d3k9ya__d2zqxb___1	Metazoa		Chordata	Firmicutes	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity [GO:0030342]; 25-hydroxycholecalciferol-24-hydroxylase activity [GO:0008403]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; osteoblast differentiation [GO:0001649]; response to vitamin D [GO:0033280]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	osteoblast differentiation [GO:0001649]; response to vitamin D [GO:0033280]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359]		mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity [GO:0030342]; 25-hydroxycholecalciferol-24-hydroxylase activity [GO:0008403]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3k9yb__d4ejge1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity [GO:0030342]; 25-hydroxycholecalciferol-24-hydroxylase activity [GO:0008403]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; osteoblast differentiation [GO:0001649]; response to vitamin D [GO:0033280]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	osteoblast differentiation [GO:0001649]; response to vitamin D [GO:0033280]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity [GO:0030342]; 25-hydroxycholecalciferol-24-hydroxylase activity [GO:0008403]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d3ka6a__d2jd67___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3kafa2_d2f21a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]
d3kanc__d3rf4a___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; cytokine receptor binding [GO:0005126]; D-dopachrome decarboxylase activity [GO:0033981]; dopachrome isomerase activity [GO:0004167]; phenylpyruvate tautomerase activity [GO:0050178]; melanin biosynthetic process [GO:0042438]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of tumor necrosis factor production [GO:0032760]	cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]	melanin biosynthetic process [GO:0042438]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of tumor necrosis factor production [GO:0032760]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]		cytokine receptor binding [GO:0005126]; D-dopachrome decarboxylase activity [GO:0033981]; dopachrome isomerase activity [GO:0004167]; phenylpyruvate tautomerase activity [GO:0050178]	cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]
d3kapa__d1d4ac___1		Metazoa	Proteobacteria	Chordata	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3kaqa__d5v8sa2__1			Proteobacteria	Thermotogae	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]					electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d3kb8a1_d4qyia___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	IMP salvage [GO:0032264]; purine ribonucleoside salvage [GO:0006166]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d3kbab__d2nw4a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; ATPase binding [GO:0051117]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclear receptor activity [GO:0004879]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]; cell-cell signaling [GO:0007267]; epithelial cell maturation [GO:0002070]; lung alveolus development [GO:0048286]; negative regulation of gene expression [GO:0010629]; ovulation from ovarian follicle [GO:0001542]; paracrine signaling [GO:0038001]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; regulation of epithelial cell proliferation [GO:0050678]; signal transduction [GO:0007165]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription initiation from RNA polymerase II promoter [GO:0006367]	axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; androgen binding [GO:0005497]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nuclear receptor activity [GO:0004879]; protein domain specific binding [GO:0019904]; ribonucleotide binding [GO:0032553]; sequence-specific DNA binding [GO:0043565]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]; androgen receptor signaling pathway [GO:0030521]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to steroid hormone stimulus [GO:0071383]; copulation [GO:0007620]; intracellular receptor signaling pathway [GO:0030522]; male courtship behavior [GO:0008049]; male sex differentiation [GO:0046661]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of integrin biosynthetic process [GO:0045720]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of penile erection [GO:0060406]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; prostate gland growth [GO:0060736]; regulation of protein localization to plasma membrane [GO:1903076]; reproductive behavior [GO:0019098]; response to estradiol [GO:0032355]; response to insulin [GO:0032868]; response to testosterone [GO:0033574]; skeletal muscle hypertrophy [GO:0014734]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	cell-cell signaling [GO:0007267]; epithelial cell maturation [GO:0002070]; lung alveolus development [GO:0048286]; negative regulation of gene expression [GO:0010629]; ovulation from ovarian follicle [GO:0001542]; paracrine signaling [GO:0038001]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; regulation of epithelial cell proliferation [GO:0050678]; signal transduction [GO:0007165]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription initiation from RNA polymerase II promoter [GO:0006367]	androgen receptor signaling pathway [GO:0030521]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to steroid hormone stimulus [GO:0071383]; copulation [GO:0007620]; intracellular receptor signaling pathway [GO:0030522]; male courtship behavior [GO:0008049]; male sex differentiation [GO:0046661]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of integrin biosynthetic process [GO:0045720]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of penile erection [GO:0060406]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; prostate gland growth [GO:0060736]; regulation of protein localization to plasma membrane [GO:1903076]; reproductive behavior [GO:0019098]; response to estradiol [GO:0032355]; response to insulin [GO:0032868]; response to testosterone [GO:0033574]; skeletal muscle hypertrophy [GO:0014734]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]	axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	ATPase binding [GO:0051117]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclear receptor activity [GO:0004879]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]	androgen binding [GO:0005497]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nuclear receptor activity [GO:0004879]; protein domain specific binding [GO:0019904]; ribonucleotide binding [GO:0032553]; sequence-specific DNA binding [GO:0043565]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]
d3kbja__d4k1gb___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	D-xylose metabolic process [GO:0042732]	base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]
d3kbpc2_d1fjma___1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; fatty acid derivative binding [GO:1901567]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine phosphatase activity [GO:0004722]; beta-catenin destruction complex disassembly [GO:1904886]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]		beta-catenin destruction complex disassembly [GO:1904886]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]	extracellular region [GO:0005576]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	fatty acid derivative binding [GO:1901567]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine phosphatase activity [GO:0004722]
d3kbpc2_d1wara1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; riboflavin metabolic process [GO:0006771]		bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; riboflavin metabolic process [GO:0006771]	extracellular region [GO:0005576]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]	acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]
d3kccb2_d4i02e2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3kcea2_d2n87a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	nucleus [GO:0005634]; mRNA binding [GO:0003729]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	nucleus [GO:0005634]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	mRNA binding [GO:0003729]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d3kcgh__d3tk5a___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d3kcoa__d5nhab___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d3kd2b__d1u2ea___1			Proteobacteria	Proteobacteria	hydrolase activity [GO:0016787]	cytoplasm [GO:0005737]; 2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity [GO:0052823]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; 3-(3-hydroxy)phenylpropionate catabolic process [GO:0019622]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]		3-(3-hydroxy)phenylpropionate catabolic process [GO:0019622]; 3-phenylpropionate catabolic process [GO:0019380]; aromatic compound catabolic process [GO:0019439]		cytoplasm [GO:0005737]	hydrolase activity [GO:0016787]	2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity [GO:0052823]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]
d3kd2b__d2h7cf___1		Metazoa	Proteobacteria	Chordata	hydrolase activity [GO:0016787]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	hydrolase activity [GO:0016787]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d3kd2c__d2h7cb___1		Metazoa	Proteobacteria	Chordata	hydrolase activity [GO:0016787]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	hydrolase activity [GO:0016787]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d3kd2d__d5alfa2__1		Metazoa	Proteobacteria	Chordata	hydrolase activity [GO:0016787]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	hydrolase activity [GO:0016787]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3kdad1_d1hbja___1		Metazoa	Proteobacteria	Chordata	hydrolase activity [GO:0016787]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]		acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	hydrolase activity [GO:0016787]	acetylcholinesterase activity [GO:0003990]
d3kdbb__d1eppe___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3kdma1_d5f7hd1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]				integral component of membrane [GO:0016021]		
d3kdnd1_d1ir1c2__1		Viridiplantae	Euryarchaeota	Streptophyta	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3kdnj1_d1iwai2__1			Euryarchaeota	Rhodophyta	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]			chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	
d3kdoa1_d1uppa1__1		Viridiplantae	Euryarchaeota	Streptophyta	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3kdob1_d1gehe2__1			Euryarchaeota	Euryarchaeota	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]			magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3kdof1_d1svda2__1			Euryarchaeota	Proteobacteria	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	reductive pentose-phosphate cycle [GO:0019253]			magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3kdoh1_d5haod1__1			Euryarchaeota	Proteobacteria	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	reductive pentose-phosphate cycle [GO:0019253]			magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	magnesium ion binding [GO:0000287]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3kdoj1_d4f0ma1__1			Euryarchaeota	Rhodophyta	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3keec__d1hpga___1				Actinobacteria	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	serine-type endopeptidase activity [GO:0004252]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]
d3keec__d2ggvb___1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; peptidase activity [GO:0008233]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive regulation of viral genome replication [GO:0045070]; RNA 5'-cap (guanine-N7)-methylation [GO:0106005]; RNA stabilization [GO:0043489]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive regulation of viral genome replication [GO:0045070]; RNA 5'-cap (guanine-N7)-methylation [GO:0106005]; RNA stabilization [GO:0043489]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; peptidase activity [GO:0008233]; protein dimerization activity [GO:0046983]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3keed__d1utka___1		Metazoa		Chordata	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular space [GO:0005615]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3keia__d4rxla___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of synapse structure or activity [GO:0050803]; response to fungicide [GO:0060992]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; ATPase-coupled molybdate transmembrane transporter activity [GO:0015412]; metal ion binding [GO:0046872]; molybdate ion transport [GO:0015689]	chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of synapse structure or activity [GO:0050803]; response to fungicide [GO:0060992]; synaptic transmission, glutamatergic [GO:0035249]	molybdate ion transport [GO:0015689]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ATPase-coupled molybdate transmembrane transporter activity [GO:0015412]; metal ion binding [GO:0046872]
d3keib__d1ce2a1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of synapse structure or activity [GO:0050803]; response to fungicide [GO:0060992]; synaptic transmission, glutamatergic [GO:0035249]	extracellular space [GO:0005615]; specific granule [GO:0042581]; iron ion binding [GO:0005506]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of synapse structure or activity [GO:0050803]; response to fungicide [GO:0060992]; synaptic transmission, glutamatergic [GO:0035249]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; terminal bouton [GO:0043195]	extracellular space [GO:0005615]; specific granule [GO:0042581]	AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	iron ion binding [GO:0005506]; serine-type endopeptidase activity [GO:0004252]
d3keja__d3edza___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d3kejb__d3f1aa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3keob2_d3gmdc___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]	negative regulation of transcription, DNA-templated [GO:0045892]; response to redox state [GO:0051775]	glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]	cytoplasm [GO:0005737]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]	coenzyme binding [GO:0050662]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]
d3kf0b__d2aogb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3kf0b__d5ozea___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3kf1b__d1xdha___1				Apicomplexa		vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]				vacuole [GO:0005773]		aspartic-type endopeptidase activity [GO:0004190]
d3kf9c__d2mjwb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; sarcomere [GO:0030017]; synapse [GO:0045202]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; myosin light chain binding [GO:0032027]; myosin light chain kinase activity [GO:0004687]; cardiac muscle contraction [GO:0060048]; cardiac muscle tissue morphogenesis [GO:0055008]; neuromuscular synaptic transmission [GO:0007274]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein autophosphorylation [GO:0046777]; regulation of muscle filament sliding [GO:0032971]; skeletal muscle cell differentiation [GO:0035914]; skeletal muscle satellite cell differentiation [GO:0014816]; striated muscle contraction [GO:0006941]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; advanced glycation end-product receptor activity [GO:0050785]; amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; S100 protein binding [GO:0044548]; scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; astrocyte activation [GO:0048143]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; glucose mediated signaling pathway [GO:0010255]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of blood circulation [GO:1903523]; negative regulation of connective tissue replacement involved in inflammatory response wound healing [GO:1904597]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of long-term synaptic potentiation [GO:1900272]; neuron projection development [GO:0031175]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein localization to membrane [GO:0072657]; regulation of CD4-positive, alpha-beta T cell activation [GO:2000514]; regulation of DNA binding [GO:0051101]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of p38MAPK cascade [GO:1900744]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell mediated cytotoxicity [GO:0001914]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to wounding [GO:0009611]; transcytosis [GO:0045056]	cardiac muscle contraction [GO:0060048]; cardiac muscle tissue morphogenesis [GO:0055008]; neuromuscular synaptic transmission [GO:0007274]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein autophosphorylation [GO:0046777]; regulation of muscle filament sliding [GO:0032971]; skeletal muscle cell differentiation [GO:0035914]; skeletal muscle satellite cell differentiation [GO:0014816]; striated muscle contraction [GO:0006941]	astrocyte activation [GO:0048143]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; glucose mediated signaling pathway [GO:0010255]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of blood circulation [GO:1903523]; negative regulation of connective tissue replacement involved in inflammatory response wound healing [GO:1904597]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of long-term synaptic potentiation [GO:1900272]; neuron projection development [GO:0031175]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein localization to membrane [GO:0072657]; regulation of CD4-positive, alpha-beta T cell activation [GO:2000514]; regulation of DNA binding [GO:0051101]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of p38MAPK cascade [GO:1900744]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell mediated cytotoxicity [GO:0001914]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to wounding [GO:0009611]; transcytosis [GO:0045056]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; sarcomere [GO:0030017]; synapse [GO:0045202]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; myosin light chain binding [GO:0032027]; myosin light chain kinase activity [GO:0004687]	advanced glycation end-product receptor activity [GO:0050785]; amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; S100 protein binding [GO:0044548]; scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]
d3kffa__d1t68x2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; vasodilation [GO:0042311]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	vasodilation [GO:0042311]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]
d3kfha__d3p6da1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d3kfia__d1mfhd___1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]		aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]		cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	
d3kfia__d3wjga___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cytosol [GO:0005829]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]		cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytosol [GO:0005829]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]	
d3kfla2_d1li7a1__1				Proteobacteria	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine-tRNA ligase activity [GO:0004825]; methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; cysteine-tRNA ligase activity [GO:0004817]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cysteinyl-tRNA aminoacylation [GO:0006423]	methionyl-tRNA aminoacylation [GO:0006431]	cysteinyl-tRNA aminoacylation [GO:0006423]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine-tRNA ligase activity [GO:0004825]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; cysteine-tRNA ligase activity [GO:0004817]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d3kfma__d1my3a___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of synapse structure or activity [GO:0050803]; response to fungicide [GO:0060992]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; regulation of synapse structure or activity [GO:0050803]; response to fungicide [GO:0060992]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3kfna__d1xn3a___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3kfna__d4gzfa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3kfnb__d5p0za___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3kfpa__d2weaa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3kfra__d1e5oe___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3kfra__d4cpsb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3kfrb__d5p5za___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3kfsa__d1bdla___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3kfsb__d5p7ma___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3kfya__d4elgc1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]		dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d3kg2a1_d2hpha___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; metal ion binding [GO:0046872]; chemotaxis [GO:0006935]; galactose transmembrane transport [GO:0015757]; methylgalactoside transport [GO:0015765]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemotaxis [GO:0006935]; galactose transmembrane transport [GO:0015757]; methylgalactoside transport [GO:0015765]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	metal ion binding [GO:0046872]
d3kgca__d4psha___1	Metazoa		Chordata	Thermotogae	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	membrane [GO:0016020]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ligand-gated ion channel activity [GO:0015276]
d3kgqa__d2pj3c___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d3kgqa__d4mxub___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	cytosol [GO:0005829]; nucleus [GO:0005634]; aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	proteolysis [GO:0006508]	aspartate catabolic process [GO:0006533]; cellular amino acid biosynthetic process [GO:0008652]; central nervous system myelination [GO:0022010]; positive regulation of oligodendrocyte differentiation [GO:0048714]	extracellular space [GO:0005615]	cytosol [GO:0005829]; nucleus [GO:0005634]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	aminoacylase activity [GO:0004046]; aspartoacylase activity [GO:0019807]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3kgsb__d1oo2b___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	extracellular region [GO:0005576]; thyroid hormone binding [GO:0070324]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	thyroid hormone binding [GO:0070324]
d3kgta__d3dgda___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3kgxb__d1qgnh___1	Metazoa	Viridiplantae	Chordata	Streptophyta	intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]	transsulfuration [GO:0019346]	intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d3kh9a1_d1syrk___1			Proteobacteria	Apicomplexa	cell [GO:0005623]; integral component of membrane [GO:0016021]; outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; integral component of membrane [GO:0016021]; outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]	disulfide oxidoreductase activity [GO:0015036]	protein disulfide oxidoreductase activity [GO:0015035]
d3khcb__d4rfrb___1			Proteobacteria	Proteobacteria	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]			1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]
d3khfb1_d2dc2a___1	Metazoa	Metazoa	Chordata	Chordata	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]		cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]	ion channel binding [GO:0044325]
d3kicm__d1vu1v___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]	
d3kicp__d3shmm___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d3kiea__d3tsxf___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]	
d3kiee__d1mvma___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	host cell nucleus [GO:0042025]; T=1 icosahedral viral capsid [GO:0039615]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; viral penetration into host nucleus [GO:0075732]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; viral penetration into host nucleus [GO:0075732]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	host cell nucleus [GO:0042025]; T=1 icosahedral viral capsid [GO:0039615]	structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d3kieg__d1vu0k___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]	
d3kieh__d3tsxi___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]	
d3kieo__d1rb8g___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; modulation by virus of host morphology or physiology [GO:0019048]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		modulation by virus of host morphology or physiology [GO:0019048]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	
d3kieo__d1vu1p___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]	
d3kiep__d1vu0h___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]	
d3kiet__d3tsxk___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]	
d3kijb__d1nswb___1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum lumen [GO:0005788]; integral component of membrane [GO:0016021]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	endoplasmic reticulum lumen [GO:0005788]; integral component of membrane [GO:0016021]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]	protein disulfide oxidoreductase activity [GO:0015035]
d3kijc__d4mf7a1__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum lumen [GO:0005788]; integral component of membrane [GO:0016021]; glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]	transferase activity [GO:0016740]	cellular response to oxidative stress [GO:0034599]		endoplasmic reticulum lumen [GO:0005788]; integral component of membrane [GO:0016021]		glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601]	transferase activity [GO:0016740]
d3kin.1_d3mjhc___1	Metazoa	Metazoa	Chordata	Chordata	apical dendrite [GO:0097440]; axon [GO:0030424]; axon cytoplasm [GO:1904115]; cell [GO:0005623]; central region of growth cone [GO:0090724]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; P-body [GO:0000932]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ATP binding [GO:0005524]; ATP-dependent microtubule motor activity, plus-end-directed [GO:0008574]; ATPase activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; anterograde axonal protein transport [GO:0099641]; anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; axon guidance [GO:0007411]; cellular response to ethanol [GO:0071361]; cellular response to nerve growth factor stimulus [GO:1990090]; cerebral cortex development [GO:0021987]; hippocampus development [GO:0021766]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; neuron development [GO:0048666]; response to rotenone [GO:1904647]; retrograde neuronal dense core vesicle transport [GO:1990049]; synaptic vesicle transport [GO:0048489]; thalamus development [GO:0021794]; vesicle-mediated transport [GO:0016192]	actin cytoskeleton [GO:0015629]; anchored component of synaptic vesicle membrane [GO:0098993]; axon [GO:0030424]; axon terminus [GO:0043679]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic side of early endosome membrane [GO:0098559]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic early endosome [GO:0098842]; ruffle [GO:0001726]; somatodendritic compartment [GO:0036477]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; amyloid-beta clearance by transcytosis [GO:0150093]; blood coagulation [GO:0007596]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of exocytosis [GO:0045921]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286]; regulation of autophagosome assembly [GO:2000785]; regulation of endosome size [GO:0051036]; regulation of filopodium assembly [GO:0051489]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465]; viral RNA genome replication [GO:0039694]	anterograde axonal protein transport [GO:0099641]; anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; axon guidance [GO:0007411]; cellular response to ethanol [GO:0071361]; cellular response to nerve growth factor stimulus [GO:1990090]; cerebral cortex development [GO:0021987]; hippocampus development [GO:0021766]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; neuron development [GO:0048666]; response to rotenone [GO:1904647]; retrograde neuronal dense core vesicle transport [GO:1990049]; synaptic vesicle transport [GO:0048489]; thalamus development [GO:0021794]; vesicle-mediated transport [GO:0016192]	amyloid-beta clearance by transcytosis [GO:0150093]; blood coagulation [GO:0007596]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of exocytosis [GO:0045921]; post-translational protein modification [GO:0043687]; Rab protein signal transduction [GO:0032482]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286]; regulation of autophagosome assembly [GO:2000785]; regulation of endosome size [GO:0051036]; regulation of filopodium assembly [GO:0051489]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic vesicle recycling [GO:0036465]; viral RNA genome replication [GO:0039694]	apical dendrite [GO:0097440]; axon [GO:0030424]; axon cytoplasm [GO:1904115]; cell [GO:0005623]; central region of growth cone [GO:0090724]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; P-body [GO:0000932]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]	actin cytoskeleton [GO:0015629]; anchored component of synaptic vesicle membrane [GO:0098993]; axon [GO:0030424]; axon terminus [GO:0043679]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; cytoplasmic side of early endosome membrane [GO:0098559]; cytosol [GO:0005829]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; early phagosome [GO:0032009]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; melanosome [GO:0042470]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; postsynaptic early endosome [GO:0098842]; ruffle [GO:0001726]; somatodendritic compartment [GO:0036477]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; ATP-dependent microtubule motor activity, plus-end-directed [GO:0008574]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d3kj4d__d1ft8b___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; presynapse [GO:0098793]; chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; Roundabout binding [GO:0048495]; signaling receptor activity [GO:0038023]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; presynapse [GO:0098793]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; Roundabout binding [GO:0048495]; signaling receptor activity [GO:0038023]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d3kj4l1_d5grxg1__1	Metazoa		Chordata		anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; presynapse [GO:0098793]; chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; Roundabout binding [GO:0048495]; signaling receptor activity [GO:0038023]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]		axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]		anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; presynapse [GO:0098793]		chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; Roundabout binding [GO:0048495]; signaling receptor activity [GO:0038023]	
d3kj4l2_d4ttdl1__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; presynapse [GO:0098793]; chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; Roundabout binding [GO:0048495]; signaling receptor activity [GO:0038023]; axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; corpus callosum development [GO:0022038]; negative chemotaxis [GO:0050919]; negative regulation of axon extension [GO:0030517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of neuron projection development [GO:0010977]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Rho protein signal transduction [GO:0035025]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	anchored component of external side of plasma membrane [GO:0031362]; axonal growth cone [GO:0044295]; cell surface [GO:0009986]; dendritic shaft [GO:0043198]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; presynapse [GO:0098793]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	chondroitin sulfate binding [GO:0035374]; ganglioside GM1 binding [GO:1905573]; ganglioside GT1b binding [GO:1905576]; heparin binding [GO:0008201]; neuregulin receptor activity [GO:0038131]; protein-containing complex binding [GO:0044877]; Roundabout binding [GO:0048495]; signaling receptor activity [GO:0038023]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3kjda2_d1a26a2__1	Metazoa	Metazoa	Chordata	Chordata	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; base-excision repair [GO:0006284]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of neuron death [GO:1901215]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; protein ADP-ribosylation [GO:0006471]; protein poly-ADP-ribosylation [GO:0070212]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA binding [GO:0003677]; NAD binding [GO:0051287]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]; ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	base-excision repair [GO:0006284]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of neuron death [GO:1901215]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; protein ADP-ribosylation [GO:0006471]; protein poly-ADP-ribosylation [GO:0070212]	ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]	DNA binding [GO:0003677]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]	DNA binding [GO:0003677]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]
d3kjra1_d3fl8c1__1			Apicomplexa	Firmicutes	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d3kk2a2_d1rbua___1				Proteobacteria	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA replication, removal of RNA primer [GO:0043137]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d3kk6b2_d3ntgd2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d3kk6b2_d5ciea___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3kkad__d1uqva1__1	Metazoa	Fungi	Chordata	Ascomycota	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	cytoplasm [GO:0005737]; protein kinase regulator activity [GO:0019887]; SAM domain binding [GO:0032093]; cell cycle arrest [GO:0007050]; cellular response to heat [GO:0034605]; osmosensory signaling MAPK cascade [GO:0000161]; osmosensory signaling pathway via Sho1 osmosensor [GO:0007232]; pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0000750]; signal transduction involved in filamentous growth [GO:0001402]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	cell cycle arrest [GO:0007050]; cellular response to heat [GO:0034605]; osmosensory signaling MAPK cascade [GO:0000161]; osmosensory signaling pathway via Sho1 osmosensor [GO:0007232]; pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0000750]; signal transduction involved in filamentous growth [GO:0001402]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	protein kinase regulator activity [GO:0019887]; SAM domain binding [GO:0032093]
d3kkeb__d2o20d___1			Actinobacteria	Firmicutes	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]	regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]		protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]	DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3kkha__d1eqtb___1		Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR1 chemokine receptor binding [GO:0031726]; CCR4 chemokine receptor binding [GO:0031729]; CCR5 chemokine receptor binding [GO:0031730]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; chemokine receptor antagonist activity [GO:0046817]; chemokine receptor binding [GO:0042379]; identical protein binding [GO:0042802]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase activator activity [GO:0016004]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein self-association [GO:0043621]; receptor signaling protein tyrosine kinase activator activity [GO:0030298]; activation of phospholipase D activity [GO:0031584]; calcium ion transport [GO:0006816]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell chemotaxis [GO:0002407]; eosinophil chemotaxis [GO:0048245]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of viral genome replication [GO:0045071]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cellular biosynthetic process [GO:0031328]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of innate immune response [GO:0045089]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphorylation [GO:0042327]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell apoptotic process [GO:0070234]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of T cell migration [GO:2000406]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of translational initiation [GO:0045948]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of viral genome replication [GO:0045070]; protein kinase B signaling [GO:0043491]; regulation of chronic inflammatory response [GO:0002676]; regulation of insulin secretion [GO:0050796]; regulation of neuron death [GO:1901214]; regulation of T cell activation [GO:0050863]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]		activation of phospholipase D activity [GO:0031584]; calcium ion transport [GO:0006816]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell chemotaxis [GO:0002407]; eosinophil chemotaxis [GO:0048245]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of viral genome replication [GO:0045071]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular biosynthetic process [GO:0031328]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of innate immune response [GO:0045089]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphorylation [GO:0042327]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell apoptotic process [GO:0070234]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of T cell migration [GO:2000406]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of translational initiation [GO:0045948]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of viral genome replication [GO:0045070]; protein kinase B signaling [GO:0043491]; regulation of chronic inflammatory response [GO:0002676]; regulation of insulin secretion [GO:0050796]; regulation of neuron death [GO:1901214]; regulation of T cell activation [GO:0050863]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]		cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		CCR1 chemokine receptor binding [GO:0031726]; CCR4 chemokine receptor binding [GO:0031729]; CCR5 chemokine receptor binding [GO:0031730]; CCR chemokine receptor binding [GO:0048020]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; chemokine receptor antagonist activity [GO:0046817]; chemokine receptor binding [GO:0042379]; identical protein binding [GO:0042802]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase activator activity [GO:0016004]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein self-association [GO:0043621]; receptor signaling protein tyrosine kinase activator activity [GO:0030298]
d3kkhb__d5l2uf___1		Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR1 chemokine receptor binding [GO:0031726]; CCR4 chemokine receptor binding [GO:0031729]; CCR5 chemokine receptor binding [GO:0031730]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; chemokine receptor antagonist activity [GO:0046817]; chemokine receptor binding [GO:0042379]; identical protein binding [GO:0042802]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase activator activity [GO:0016004]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein self-association [GO:0043621]; receptor signaling protein tyrosine kinase activator activity [GO:0030298]; activation of phospholipase D activity [GO:0031584]; calcium ion transport [GO:0006816]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell chemotaxis [GO:0002407]; eosinophil chemotaxis [GO:0048245]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of viral genome replication [GO:0045071]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cellular biosynthetic process [GO:0031328]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of innate immune response [GO:0045089]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphorylation [GO:0042327]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell apoptotic process [GO:0070234]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of T cell migration [GO:2000406]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of translational initiation [GO:0045948]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of viral genome replication [GO:0045070]; protein kinase B signaling [GO:0043491]; regulation of chronic inflammatory response [GO:0002676]; regulation of insulin secretion [GO:0050796]; regulation of neuron death [GO:1901214]; regulation of T cell activation [GO:0050863]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]		activation of phospholipase D activity [GO:0031584]; calcium ion transport [GO:0006816]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell chemotaxis [GO:0002407]; eosinophil chemotaxis [GO:0048245]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of viral genome replication [GO:0045071]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of activation of Janus kinase activity [GO:0010536]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular biosynthetic process [GO:0031328]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of innate immune response [GO:0045089]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of natural killer cell chemotaxis [GO:2000503]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphorylation [GO:0042327]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell apoptotic process [GO:0070234]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of T cell migration [GO:2000406]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of translational initiation [GO:0045948]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of viral genome replication [GO:0045070]; protein kinase B signaling [GO:0043491]; regulation of chronic inflammatory response [GO:0002676]; regulation of insulin secretion [GO:0050796]; regulation of neuron death [GO:1901214]; regulation of T cell activation [GO:0050863]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]		cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		CCR1 chemokine receptor binding [GO:0031726]; CCR4 chemokine receptor binding [GO:0031729]; CCR5 chemokine receptor binding [GO:0031730]; CCR chemokine receptor binding [GO:0048020]; chemoattractant activity [GO:0042056]; chemokine activity [GO:0008009]; chemokine receptor antagonist activity [GO:0046817]; chemokine receptor binding [GO:0042379]; identical protein binding [GO:0042802]; phosphatidylinositol phospholipase C activity [GO:0004435]; phospholipase activator activity [GO:0016004]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein self-association [GO:0043621]; receptor signaling protein tyrosine kinase activator activity [GO:0030298]
d3kkkb__d2hpac___1		Metazoa	Apicomplexa	Chordata	cytosol [GO:0005829]; phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]; adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	glycolytic process [GO:0006096]	adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	cytosol [GO:0005829]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	phosphoglycerate mutase activity [GO:0004619]	5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]
d3kkkc__d1nd6a___1		Metazoa	Apicomplexa	Chordata	cytosol [GO:0005829]; phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]; adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	glycolytic process [GO:0006096]	adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	cytosol [GO:0005829]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	phosphoglycerate mutase activity [GO:0004619]	5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]
d3kkkc__d4pgma___1		Fungi	Apicomplexa	Ascomycota	cytosol [GO:0005829]; phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	phosphoglycerate mutase activity [GO:0004619]	phosphoglycerate mutase activity [GO:0004619]
d3kkkd__d1nd6d___1		Metazoa	Apicomplexa	Chordata	cytosol [GO:0005829]; phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; 5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]; adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	glycolytic process [GO:0006096]	adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; neutrophil degranulation [GO:0043312]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	cytosol [GO:0005829]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	phosphoglycerate mutase activity [GO:0004619]	5'-nucleotidase activity [GO:0008253]; acid phosphatase activity [GO:0003993]; identical protein binding [GO:0042802]; lysophosphatidic acid phosphatase activity [GO:0052642]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; thiamine phosphate phosphatase activity [GO:0042131]
d3kkpa__d4bfvb___1	Metazoa		Chordata	Actinobacteria	plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; cellular response to leukemia inhibitory factor [GO:1990830]; Ras protein signal transduction [GO:0007265]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cellular response to leukemia inhibitory factor [GO:1990830]; Ras protein signal transduction [GO:0007265]	coenzyme A biosynthetic process [GO:0015937]	plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d3kkqa__d1gvnb___1	Metazoa		Chordata	Firmicutes	plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; cellular response to leukemia inhibitory factor [GO:1990830]; Ras protein signal transduction [GO:0007265]	toxic substance binding [GO:0015643]; negative regulation of cell killing [GO:0031342]; response to toxic substance [GO:0009636]	cellular response to leukemia inhibitory factor [GO:1990830]; Ras protein signal transduction [GO:0007265]	negative regulation of cell killing [GO:0031342]; response to toxic substance [GO:0009636]	plasma membrane [GO:0005886]		GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]	toxic substance binding [GO:0015643]
d3kksa1_d5vqqa2__1					host cell [GO:0043657]; viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell [GO:0043657]; viral nucleocapsid [GO:0019013]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3kkta__d4htzd___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d3kkua__d5tl7d2__1		Metazoa		Chordata	cysteine-type endopeptidase activity [GO:0004197]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]		defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	cysteine-type endopeptidase activity [GO:0004197]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3kkwa1_d4r57g___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]	cytoplasm [GO:0005737]; diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]; polyamine catabolic process [GO:0006598]		polyamine catabolic process [GO:0006598]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]	diamine N-acetyltransferase activity [GO:0004145]; magnesium ion binding [GO:0000287]
d3kkyb2_d2w7wa2__1			Deinococcus-Thermus	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3klab1_d4ozhf1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3km2f__d1srdc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	chloroplast [GO:0009507]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	removal of superoxide radicals [GO:0019430]		chloroplast [GO:0009507]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	chloroplast [GO:0009507]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3km2g__d4rvpc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	removal of superoxide radicals [GO:0019430]		chloroplast [GO:0009507]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3km6a2_d1xw6a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d3km6a2_d3q18b2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d3km6b1_d3zvjd___1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d3km6b2_d10gsb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3kmb21_d2xr6a___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]
d3kmda__d1pzul2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3kmdc__d2i9tb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3kmnb1_d1yf1g___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; cytosol [GO:0005829]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	thioredoxin peroxidase activity [GO:0008379]
d3kmoa1_d3hvxd___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]
d3kmoa1_d4dejl1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	transferase activity [GO:0016740]
d3kmoa2_d2jl4b2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; maleylpyruvate isomerase activity [GO:0050077]; aromatic amino acid family metabolic process [GO:0009072]; aromatic compound catabolic process [GO:0019439]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	aromatic amino acid family metabolic process [GO:0009072]; aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	maleylpyruvate isomerase activity [GO:0050077]
d3kmob1_d5g5aa1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; 2,4,6-trinitrotoluene catabolic process [GO:0046256]; glutathione metabolic process [GO:0006749]; toxin catabolic process [GO:0009407]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	2,4,6-trinitrotoluene catabolic process [GO:0046256]; glutathione metabolic process [GO:0006749]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione transferase activity [GO:0004364]
d3kmob2_d1gsfd1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3kmpa__d1ozja___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear inner membrane [GO:0005637]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; BMP signaling pathway [GO:0030509]; bone development [GO:0060348]; cardiac muscle cell proliferation [GO:0060038]; cartilage development [GO:0051216]; cellular response to BMP stimulus [GO:0071773]; cellular response to organic cyclic compound [GO:0071407]; embryonic pattern specification [GO:0009880]; gamete generation [GO:0007276]; hindbrain development [GO:0030902]; homeostatic process [GO:0042592]; inflammatory response [GO:0006954]; MAPK cascade [GO:0000165]; mesodermal cell fate commitment [GO:0001710]; midbrain development [GO:0030901]; negative regulation of cell population proliferation [GO:0008285]; osteoblast fate commitment [GO:0002051]; positive regulation of cartilage development [GO:0061036]; positive regulation of cell differentiation [GO:0045597]; positive regulation of gene expression [GO:0010628]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; protein phosphorylation [GO:0006468]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heteromeric SMAD protein complex [GO:0071144]; nuclear chromatin [GO:0000790]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]; beta-catenin binding [GO:0008013]; bHLH transcription factor binding [GO:0043425]; chromatin DNA binding [GO:0031490]; co-SMAD binding [GO:0070410]; collagen binding [GO:0005518]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; glucocorticoid receptor binding [GO:0035259]; identical protein binding [GO:0042802]; mineralocorticoid receptor binding [GO:0031962]; phosphatase binding [GO:0019902]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; proximal promoter sequence-specific DNA binding [GO:0000987]; R-SMAD binding [GO:0070412]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transforming growth factor beta receptor binding [GO:0005160]; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [GO:0030618]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activin receptor signaling pathway [GO:0032924]; adrenal gland development [GO:0030325]; cell cycle arrest [GO:0007050]; cell-cell junction organization [GO:0045216]; cellular response to cytokine stimulus [GO:0071345]; cellular response to transforming growth factor beta stimulus [GO:0071560]; developmental growth [GO:0048589]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic foregut morphogenesis [GO:0048617]; embryonic pattern specification [GO:0009880]; endoderm development [GO:0007492]; evasion or tolerance of host defenses by virus [GO:0019049]; extrinsic apoptotic signaling pathway [GO:0097191]; heart looping [GO:0001947]; immune response [GO:0006955]; immune system development [GO:0002520]; in utero embryonic development [GO:0001701]; lens fiber cell differentiation [GO:0070306]; liver development [GO:0001889]; mesoderm formation [GO:0001707]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of cell growth [GO:0030308]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of inflammatory response [GO:0050728]; negative regulation of lung blood pressure [GO:0061767]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; nodal signaling pathway [GO:0038092]; osteoblast development [GO:0002076]; paraxial mesoderm morphogenesis [GO:0048340]; pericardium development [GO:0060039]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of bone mineralization [GO:0030501]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta3 production [GO:0032916]; primary miRNA processing [GO:0031053]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of binding [GO:0051098]; regulation of epithelial cell proliferation [GO:0050678]; regulation of immune response [GO:0050776]; regulation of striated muscle tissue development [GO:0016202]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; signal transduction involved in regulation of gene expression [GO:0023019]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somitogenesis [GO:0001756]; T cell activation [GO:0042110]; thyroid gland development [GO:0030878]; transdifferentiation [GO:0060290]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]	BMP signaling pathway [GO:0030509]; bone development [GO:0060348]; cardiac muscle cell proliferation [GO:0060038]; cartilage development [GO:0051216]; cellular response to BMP stimulus [GO:0071773]; cellular response to organic cyclic compound [GO:0071407]; embryonic pattern specification [GO:0009880]; gamete generation [GO:0007276]; hindbrain development [GO:0030902]; homeostatic process [GO:0042592]; inflammatory response [GO:0006954]; MAPK cascade [GO:0000165]; mesodermal cell fate commitment [GO:0001710]; midbrain development [GO:0030901]; negative regulation of cell population proliferation [GO:0008285]; osteoblast fate commitment [GO:0002051]; positive regulation of cartilage development [GO:0061036]; positive regulation of cell differentiation [GO:0045597]; positive regulation of gene expression [GO:0010628]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; protein phosphorylation [GO:0006468]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activin receptor signaling pathway [GO:0032924]; adrenal gland development [GO:0030325]; cell-cell junction organization [GO:0045216]; cell cycle arrest [GO:0007050]; cellular response to cytokine stimulus [GO:0071345]; cellular response to transforming growth factor beta stimulus [GO:0071560]; developmental growth [GO:0048589]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic foregut morphogenesis [GO:0048617]; embryonic pattern specification [GO:0009880]; endoderm development [GO:0007492]; evasion or tolerance of host defenses by virus [GO:0019049]; extrinsic apoptotic signaling pathway [GO:0097191]; heart looping [GO:0001947]; immune response [GO:0006955]; immune system development [GO:0002520]; in utero embryonic development [GO:0001701]; lens fiber cell differentiation [GO:0070306]; liver development [GO:0001889]; mesoderm formation [GO:0001707]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of cell growth [GO:0030308]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of inflammatory response [GO:0050728]; negative regulation of lung blood pressure [GO:0061767]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; nodal signaling pathway [GO:0038092]; osteoblast development [GO:0002076]; paraxial mesoderm morphogenesis [GO:0048340]; pericardium development [GO:0060039]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of bone mineralization [GO:0030501]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta3 production [GO:0032916]; primary miRNA processing [GO:0031053]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of binding [GO:0051098]; regulation of epithelial cell proliferation [GO:0050678]; regulation of immune response [GO:0050776]; regulation of striated muscle tissue development [GO:0016202]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta2 production [GO:0032909]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to hypoxia [GO:0001666]; signal transduction involved in regulation of gene expression [GO:0023019]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somitogenesis [GO:0001756]; T cell activation [GO:0042110]; thyroid gland development [GO:0030878]; transdifferentiation [GO:0060290]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; nuclear inner membrane [GO:0005637]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heteromeric SMAD protein complex [GO:0071144]; nuclear chromatin [GO:0000790]; nuclear inner membrane [GO:0005637]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]	co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]	beta-catenin binding [GO:0008013]; bHLH transcription factor binding [GO:0043425]; chromatin DNA binding [GO:0031490]; collagen binding [GO:0005518]; co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; glucocorticoid receptor binding [GO:0035259]; identical protein binding [GO:0042802]; mineralocorticoid receptor binding [GO:0031962]; phosphatase binding [GO:0019902]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; R-SMAD binding [GO:0070412]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [GO:0030618]; transforming growth factor beta receptor binding [GO:0005160]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d3kmta__d1n3jb___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	identical protein binding [GO:0042802]; methyltransferase activity [GO:0008168]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	identical protein binding [GO:0042802]; methyltransferase activity [GO:0008168]
d3kmtc__d5ww0b1__1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; histone methyltransferase activity (H3-K37 specific) [GO:0062122]; histone H3-K36 methylation [GO:0010452]; histone lysine methylation [GO:0034968]	blood coagulation [GO:0007596]; cellular protein metabolic process [GO:0044267]; chromatin organization [GO:0006325]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of gene expression, epigenetic [GO:0045814]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing [GO:0060968]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere organization [GO:0032200]	histone H3-K36 methylation [GO:0010452]; histone lysine methylation [GO:0034968]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	histone methyltransferase activity (H3-K37 specific) [GO:0062122]
d3kmxb__d2hpfa___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3kmya__d3jw2b___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3kmyb__d5fiva___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d3kn0b__d2pk5b___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3kn7a__d5mfqb___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d3knqa2_d2g3pa2__1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; pathogenesis [GO:0009405]; viral entry into host cell via pilus basal pore [GO:0039668]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; pathogenesis [GO:0009405]; viral entry into host cell via pilus basal pore [GO:0039668]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; pathogenesis [GO:0009405]; viral entry into host cell via pilus basal pore [GO:0039668]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; entry receptor-mediated virion attachment to host cell [GO:0098670]; pathogenesis [GO:0009405]; viral entry into host cell via pilus basal pore [GO:0039668]; viral extrusion [GO:0099045]; virion attachment to host cell pilus [GO:0039666]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]		
d3knra__d4rama___1			Firmicutes	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d3ko0b__d2jxca___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]; clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]
d3ko0c__d1ej3b___1	Metazoa	Metazoa	Chordata	Cnidaria	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	bioluminescence [GO:0008218]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]		actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	calcium ion binding [GO:0005509]
d3ko0h__d2hetd___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; calcium ion binding [GO:0005509]; phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	calcium ion binding [GO:0005509]
d3ko0o__d1k90d___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d3ko0r__d2yggb1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]; activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	activation of adenylate cyclase activity [GO:0007190]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to mitochondrial membrane [GO:0090151]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of DNA binding [GO:0043388]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of store-operated calcium channel activity [GO:1901339]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to amphetamine [GO:0001975]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; voltage-gated potassium channel complex [GO:0008076]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium channel regulator activity [GO:0005246]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase regulator activity [GO:0030235]; N-terminal myristoylation domain binding [GO:0031997]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase activator activity [GO:0072542]; titin binding [GO:0031432]; type 3 metabotropic glutamate receptor binding [GO:0031800]
d3ko6a__d3nopc2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]; cellular response to oxidative stress [GO:0034599]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cellular response to oxidative stress [GO:0034599]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3ko7b__d3pd5a___1			Apicomplexa	Euryarchaeota	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; D-tyrosyl-tRNA(Tyr) deacylase activity [GO:0051500]; Gly-tRNA(Ala) hydrolase activity [GO:0106026]; nucleotide binding [GO:0000166]; tRNA binding [GO:0000049]; tRNA metabolic process [GO:0006399]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; threonyl-tRNA aminoacylation [GO:0006435]	tRNA metabolic process [GO:0006399]	threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; D-tyrosyl-tRNA(Tyr) deacylase activity [GO:0051500]; Gly-tRNA(Ala) hydrolase activity [GO:0106026]; nucleotide binding [GO:0000166]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d3kofa__d1fwta___1			Proteobacteria	Aquificae	cytosol [GO:0005829]; membrane [GO:0016020]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]
d3kofa__d3lbcb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d3kooa1_d4umfc1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipopolysaccharide biosynthetic process [GO:0009103]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d3koua__d5bnfb___1	Metazoa	Metazoa	Chordata	Chordata	plasma membrane [GO:0005886]; NAD glycohydrolase activity [GO:0061810]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]; metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]; positive regulation of B cell proliferation [GO:0030890]	metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	positive regulation of B cell proliferation [GO:0030890]	plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD glycohydrolase activity [GO:0061810]; phosphorus-oxygen lyase activity [GO:0016849]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]
d3kpbb__d1pvmb4__1			Euryarchaeota	Euryarchaeota		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d3kpdb__d2ooye1__1		Fungi	Euryarchaeota	Ascomycota		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; protein kinase activator activity [GO:0030295]; carbohydrate metabolic process [GO:0005975]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]		carbohydrate metabolic process [GO:0005975]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]		AMP binding [GO:0016208]; ATP binding [GO:0005524]; protein kinase activator activity [GO:0030295]
d3kpdd__d5isof1__1		Metazoa	Euryarchaeota	Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; AMP-activated protein kinase activity [GO:0004679]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; cell cycle arrest [GO:0007050]; fatty acid biosynthetic process [GO:0006633]; macroautophagy [GO:0016236]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of signal transduction by p53 class mediator [GO:1901796]; signal transduction [GO:0007165]		cell cycle arrest [GO:0007050]; fatty acid biosynthetic process [GO:0006633]; macroautophagy [GO:0016236]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of signal transduction by p53 class mediator [GO:1901796]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]		AMP-activated protein kinase activity [GO:0004679]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]
d3kpjb1_d3r0qe___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytosol [GO:0005829]; [myelin basic protein]-arginine N-methyltransferase activity [GO:0016277]; histone-arginine N-methyltransferase activity [GO:0008469]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; vegetative to reproductive phase transition of meristem [GO:0010228]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; vegetative to reproductive phase transition of meristem [GO:0010228]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	phenylethanolamine N-methyltransferase activity [GO:0004603]	[myelin basic protein]-arginine N-methyltransferase activity [GO:0016277]; histone-arginine N-methyltransferase activity [GO:0008469]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]
d3kpla2_d3nn8d1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3kpla2_d5whkl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3kpma1_d3pl6a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3kpma1_d4l3cu1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3kpma2_d6emjl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3kpnb__d2rcjr1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3kpoa1_d1vada2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3kpoa2_d1ovza2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to interferon-alpha [GO:0035457]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; Fc receptor signaling pathway [GO:0038093]; immune response [GO:0006955]; neutrophil activation [GO:0042119]; neutrophil degranulation [GO:0043312]; neutrophil mediated immunity [GO:0002446]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of oxidative stress-induced cell death [GO:1903209]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	IgA binding [GO:0019862]; IgA receptor activity [GO:0019766]
d3kpoa2_d4nztl2__1	Metazoa		Chordata	Tenericutes	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3kppb__d1fbil2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3kppb__d5wuxd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d3kpqa1_d5m00a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3kprd1_d4ypgl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell surface receptor signaling pathway [GO:0007166]; cell-cell signaling [GO:0007267]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; natural killer cell activation involved in immune response [GO:0002323]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-5 secretion [GO:2000663]; negative regulation of T cell differentiation [GO:0045581]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]
d3kpre2_d43cag___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3kprf1_d3ftga1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3kprg__d5chnl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3kpri1_d3qq9l1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3kpsb__d3mugc2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3kpsb__d4kq3l1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3kpsd1_d1ucbl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3kpse2_d3qo1a1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3kpub1_d5k09d___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	phenylethanolamine N-methyltransferase activity [GO:0004603]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d3kpva__d3lgab___1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	tRNA (m1A) methyltransferase complex [GO:0031515]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	tRNA (m1A) methyltransferase complex [GO:0031515]	phenylethanolamine N-methyltransferase activity [GO:0004603]	tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]
d3kpwa__d5cvdb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cell [GO:0005623]; chromosome, centromeric region [GO:0000775]; condensed chromosome inner kinetochore [GO:0000939]; condensed nuclear chromosome kinetochore [GO:0000778]; condensed nuclear chromosome, centromeric region [GO:0000780]; cytosol [GO:0005829]; nuclear nucleosome [GO:0000788]; nuclear pericentric heterochromatin [GO:0031618]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; CENP-A containing nucleosome assembly [GO:0034080]; establishment of mitotic spindle orientation [GO:0000132]; kinetochore assembly [GO:0051382]; mitotic cytokinesis [GO:0000281]; protein localization to chromosome, centromeric region [GO:0071459]; viral process [GO:0016032]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	CENP-A containing nucleosome assembly [GO:0034080]; establishment of mitotic spindle orientation [GO:0000132]; kinetochore assembly [GO:0051382]; mitotic cytokinesis [GO:0000281]; protein localization to chromosome, centromeric region [GO:0071459]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cell [GO:0005623]; chromosome, centromeric region [GO:0000775]; condensed chromosome inner kinetochore [GO:0000939]; condensed nuclear chromosome, centromeric region [GO:0000780]; condensed nuclear chromosome kinetochore [GO:0000778]; cytosol [GO:0005829]; nuclear nucleosome [GO:0000788]; nuclear pericentric heterochromatin [GO:0031618]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	phenylethanolamine N-methyltransferase activity [GO:0004603]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3kpya__d4pgha2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	acetylserotonin O-methyltransferase activity [GO:0017096]; caffeate O-methyltransferase activity [GO:0047763]; luteolin O-methyltransferase activity [GO:0030744]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; aromatic compound biosynthetic process [GO:0019438]; flavonol biosynthetic process [GO:0051555]; lignin biosynthetic process [GO:0009809]; melatonin biosynthetic process [GO:0030187]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	aromatic compound biosynthetic process [GO:0019438]; flavonol biosynthetic process [GO:0051555]; lignin biosynthetic process [GO:0009809]; melatonin biosynthetic process [GO:0030187]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		phenylethanolamine N-methyltransferase activity [GO:0004603]	acetylserotonin O-methyltransferase activity [GO:0017096]; caffeate O-methyltransferase activity [GO:0047763]; luteolin O-methyltransferase activity [GO:0030744]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d3kqba__d2z94a___1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; 3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; 7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	7-methylguanosine mRNA capping [GO:0006370]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host autophagy [GO:0039519]; modulation by virus of host protein ubiquitination [GO:0039648]; mRNA methylation [GO:0080009]; positive regulation of ubiquitin-specific protease activity [GO:2000158]; positive stranded viral RNA replication [GO:0039690]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation [GO:0039604]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; transcription, RNA-templated [GO:0001172]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; viral transcription [GO:0019083]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	cytoplasmic viral factory [GO:0039714]; host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	3'-5'-exoribonuclease activity [GO:0000175]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; double-stranded RNA binding [GO:0003725]; endonuclease activity [GO:0004519]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; Lys48-specific deubiquitinase activity [GO:1990380]; methyltransferase activity [GO:0008168]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; single-stranded RNA binding [GO:0003727]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3kqba__d3w94a___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	membrane [GO:0016020]; serine-type endopeptidase activity [GO:0004252]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	membrane [GO:0016020]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d3kqda__d1ct2e___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase inhibitor activity [GO:0004867]
d3kqge1_d2ox9d___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; low-density lipoprotein particle binding [GO:0030169]; metal ion binding [GO:0046872]; signaling pattern recognition receptor activity [GO:0008329]; transmembrane signaling receptor activity [GO:0004888]; cellular response to exogenous dsRNA [GO:0071360]; immune response [GO:0006955]; phagocytosis, recognition [GO:0006910]; positive regulation of cell adhesion molecule production [GO:0060355]; toll-like receptor 3 signaling pathway [GO:0034138]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cellular response to exogenous dsRNA [GO:0071360]; immune response [GO:0006955]; phagocytosis, recognition [GO:0006910]; positive regulation of cell adhesion molecule production [GO:0060355]; toll-like receptor 3 signaling pathway [GO:0034138]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; low-density lipoprotein particle binding [GO:0030169]; metal ion binding [GO:0046872]; signaling pattern recognition receptor activity [GO:0008329]; transmembrane signaling receptor activity [GO:0004888]
d3kqge1_d4j6me___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d3kqgf1_d1x2wb___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; toxin activity [GO:0090729]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]		clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	calcium ion binding [GO:0005509]; toxin activity [GO:0090729]
d3kqhb1_d2jj2m2__1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	ATP synthesis coupled proton transport [GO:0015986]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3kqhb2_d2jlua1__1					extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3kqkb1_d8ohma1__1					extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3kqlb1_d1heib2__1					extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]
d3kqlb1_d5ep2a1__1				Proteobacteria	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d3kqma__d1kyze2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]; lignin biosynthetic process [GO:0009809]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	lignin biosynthetic process [GO:0009809]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		phenylethanolamine N-methyltransferase activity [GO:0004603]	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]
d3kqob1_d2ibsa1__1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]; DNA restriction-modification system [GO:0009307]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	DNA restriction-modification system [GO:0009307]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		phenylethanolamine N-methyltransferase activity [GO:0004603]	DNA binding [GO:0003677]; site-specific DNA-methyltransferase (adenine-specific) activity [GO:0009007]
d3kqpb1_d2aowb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; histamine N-methyltransferase activity [GO:0046539]; brain development [GO:0007420]; histamine catabolic process [GO:0001695]; histidine catabolic process [GO:0006548]; hyperosmotic response [GO:0006972]; methylation [GO:0032259]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to amine [GO:0014075]; response to cocaine [GO:0042220]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to interleukin-1 [GO:0070555]; response to tumor cell [GO:0002347]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	brain development [GO:0007420]; histamine catabolic process [GO:0001695]; histidine catabolic process [GO:0006548]; hyperosmotic response [GO:0006972]; methylation [GO:0032259]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to amine [GO:0014075]; response to cocaine [GO:0042220]; response to glucocorticoid [GO:0051384]; response to immobilization stress [GO:0035902]; response to interleukin-1 [GO:0070555]; response to tumor cell [GO:0002347]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]	phenylethanolamine N-methyltransferase activity [GO:0004603]	histamine N-methyltransferase activity [GO:0046539]
d3kqqa__d2bm8c___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	lipid biosynthetic process [GO:0008610]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		phenylethanolamine N-methyltransferase activity [GO:0004603]	methyltransferase activity [GO:0008168]
d3kqra__d2e7ta___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]
d3kqrb__d1gnhb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d3kqrd__d2d3sd___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]
d3kqta__d5mhta___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	DNA restriction-modification system [GO:0009307]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		phenylethanolamine N-methyltransferase activity [GO:0004603]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d3kqua2_d2afip___1				Proteobacteria	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	nitrogen fixation [GO:0009399]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	molybdenum-iron nitrogenase complex [GO:0016612]	actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d3kquc1_d1heia1__1					extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]
d3kqvb1_d2opbb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	phenylethanolamine N-methyltransferase activity [GO:0004603]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d3kqwb1_d1yz3a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	phenylethanolamine N-methyltransferase activity [GO:0004603]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d3kr2b1_d1ri4a___1	Metazoa	Fungi	Chordata	Microsporidia	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	nucleus [GO:0005634]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; RNA binding [GO:0003723]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	nucleus [GO:0005634]	phenylethanolamine N-methyltransferase activity [GO:0004603]	mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; RNA binding [GO:0003723]
d3kr3l2_d5vicl1__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; insulin receptor binding [GO:0005158]; insulin-like growth factor receptor binding [GO:0005159]; integrin binding [GO:0005178]; protein serine/threonine kinase activator activity [GO:0043539]; receptor ligand activity [GO:0048018]; animal organ morphogenesis [GO:0009887]; cellular protein metabolic process [GO:0044267]; embryonic placenta development [GO:0001892]; embryonic placenta morphogenesis [GO:0060669]; exocrine pancreas development [GO:0031017]; glucose metabolic process [GO:0006006]; in utero embryonic development [GO:0001701]; insulin receptor signaling pathway [GO:0008286]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; multicellular organism development [GO:0007275]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; platelet degranulation [GO:0002576]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of glycogen (starch) synthase activity [GO:2000467]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; regulation of transcription, DNA-templated [GO:0006355]; skeletal system development [GO:0001501]; striated muscle cell differentiation [GO:0051146]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	animal organ morphogenesis [GO:0009887]; cellular protein metabolic process [GO:0044267]; embryonic placenta development [GO:0001892]; embryonic placenta morphogenesis [GO:0060669]; exocrine pancreas development [GO:0031017]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; in utero embryonic development [GO:0001701]; multicellular organism development [GO:0007275]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; platelet degranulation [GO:0002576]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of glycogen (starch) synthase activity [GO:2000467]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; regulation of transcription, DNA-templated [GO:0006355]; skeletal system development [GO:0001501]; striated muscle cell differentiation [GO:0051146]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	growth factor activity [GO:0008083]; hormone activity [GO:0005179]; insulin-like growth factor receptor binding [GO:0005159]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; protein serine/threonine kinase activator activity [GO:0043539]; receptor ligand activity [GO:0048018]	protein dimerization activity [GO:0046983]
d3krdt__d4no8f___1		Fungi	Actinobacteria	Ascomycota	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3krfd1_d2f94f___1	Viridiplantae	Metazoa	Streptophyta	Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]		cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]		dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3krod1_d2f89f___1	Viridiplantae	Metazoa	Streptophyta	Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]		cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]		dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3krod1_d3wcgc___1	Viridiplantae		Streptophyta			integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]; ergosterol biosynthetic process [GO:0006696]		ergosterol biosynthetic process [GO:0006696]		integral component of membrane [GO:0016021]		farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]
d3krsb__d2yc8r___1			Apicomplexa		triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]				triose-phosphate isomerase activity [GO:0004807]	
d3krua__d1vysx___1			Firmicutes	Proteobacteria	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3kruc__d3w84a___1			Firmicutes		FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d3krxb__d2co0c___1	Metazoa	Metazoa	Chordata	Chordata	cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]; alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]; cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of catecholamine secretion [GO:0033605]; receptor internalization [GO:0031623]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of catecholamine secretion [GO:0033605]; receptor internalization [GO:0031623]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]
d3kryb__d1lnee___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3kryb__d2oxwa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3kryc__d1tlxa___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3ks0b__d4b8na___1	Fungi		Ascomycota		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]		heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3ks0j2_d3o6kl1__1	Fungi		Ascomycota		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]		lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]		heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]	
d3ks0j2_d5mepd2__1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ks0l1_d1r0ah1__1	Fungi		Ascomycota		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ks0l1_d4r7dd1__1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]		lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]		heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]	
d3ks1a__d5dvxa___1		Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]		bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]		basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]		carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3ksfa__d2o9aa2__1				Proteobacteria		cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; glyoxylate cycle [GO:0006097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]		glyoxylate cycle [GO:0006097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]		cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3ksfb__d3ko6a___1		Fungi		Ascomycota		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]; cellular response to oxidative stress [GO:0034599]		cellular response to oxidative stress [GO:0034599]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]
d3ksfc__d2o9ad2__1				Proteobacteria		cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; glyoxylate cycle [GO:0006097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]		glyoxylate cycle [GO:0006097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]		cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3ksfe__d3nhqc2__1				Proteobacteria		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]				ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3ksff__d1f5mb___1		Fungi		Ascomycota		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]; cellular response to oxidative stress [GO:0034599]		cellular response to oxidative stress [GO:0034599]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]
d3ksff__d3g6oa2__1				Proteobacteria		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]				ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3ksfg__d2oolb1__1				Proteobacteria		identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]				identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]
d3ksha__d3c2wh1__1				Proteobacteria		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]				ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3ksla__d1n4sa___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d3ksqb__d1tnyf___1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d3ksva__d4zklb___1		Metazoa		Chordata	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; nucleotide metabolic process [GO:0009117]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	nucleotide metabolic process [GO:0009117]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d3kt2a1_d4l6ba___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	aspartic-type endopeptidase activity [GO:0004190]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3kt5a2_d5p6qa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	aspartic-type endopeptidase activity [GO:0004190]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3kt6b__d1ihob___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantoate-beta-alanine ligase activity [GO:0004592]; pantothenate biosynthetic process from valine [GO:0033317]	tryptophanyl-tRNA aminoacylation [GO:0006436]	pantothenate biosynthetic process from valine [GO:0033317]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantoate-beta-alanine ligase activity [GO:0004592]
d3kt6b__d1vbna___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]; tRNA aminoacylation [GO:0043039]; tyrosyl-tRNA aminoacylation [GO:0006437]	tryptophanyl-tRNA aminoacylation [GO:0006436]	tRNA aminoacylation [GO:0043039]; tyrosyl-tRNA aminoacylation [GO:0006437]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; RNA binding [GO:0003723]; tyrosine-tRNA ligase activity [GO:0004831]
d3kt6d__d4muga___1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantoate-beta-alanine ligase activity [GO:0004592]; pantothenate biosynthetic process [GO:0015940]	tryptophanyl-tRNA aminoacylation [GO:0006436]	pantothenate biosynthetic process [GO:0015940]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantoate-beta-alanine ligase activity [GO:0004592]
d3kt9a__d1k3qa___1	Metazoa	Fungi	Chordata	Ascomycota	chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA 5'-adenosine monophosphate hydrolase activity [GO:0033699]; DNA-3'-diphospho-5'-guanosine diphosphatase [GO:0120108]; double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mismatched DNA binding [GO:0030983]; phosphoglycolate phosphatase activity [GO:0008967]; phosphoprotein binding [GO:0051219]; polynucleotide 3'-phosphatase activity [GO:0046403]; protein N-terminus binding [GO:0047485]; single-strand break-containing DNA binding [GO:1990165]; single-stranded DNA binding [GO:0003697]; cellular response to DNA damage stimulus [GO:0006974]; DNA ligation [GO:0006266]; double-strand break repair [GO:0006302]; regulation of protein stability [GO:0031647]; response to hydrogen peroxide [GO:0042542]; single strand break repair [GO:0000012]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein tyrosine kinase activity [GO:0004713]; deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	cellular response to DNA damage stimulus [GO:0006974]; DNA ligation [GO:0006266]; double-strand break repair [GO:0006302]; regulation of protein stability [GO:0031647]; response to hydrogen peroxide [GO:0042542]; single strand break repair [GO:0000012]	deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of phosphorylation [GO:0042326]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; signal transduction in response to DNA damage [GO:0042770]	chromatin [GO:0000785]; cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA-3'-diphospho-5'-guanosine diphosphatase [GO:0120108]; DNA 5'-adenosine monophosphate hydrolase activity [GO:0033699]; double-stranded DNA binding [GO:0003690]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mismatched DNA binding [GO:0030983]; phosphoglycolate phosphatase activity [GO:0008967]; phosphoprotein binding [GO:0051219]; polynucleotide 3'-phosphatase activity [GO:0046403]; protein N-terminus binding [GO:0047485]; single-strand break-containing DNA binding [GO:1990165]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; protein kinase activity [GO:0004672]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]
d3ktgb1_d3r9tb___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	catalytic activity [GO:0003824]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]		ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]	catalytic activity [GO:0003824]
d3ktja__d4i4za___1			Firmicutes	Cyanobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; menaquinone biosynthetic process [GO:0009234]; phylloquinone biosynthetic process [GO:0042372]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	menaquinone biosynthetic process [GO:0009234]; phylloquinone biosynthetic process [GO:0042372]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cytosol [GO:0005829]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]	1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]
d3ktje__d2zl2a___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d3ktka__d2zqrc___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]	enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]
d3ktkj__d4i42l___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; bicarbonate binding [GO:0071890]; menaquinone biosynthetic process [GO:0009234]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	menaquinone biosynthetic process [GO:0009234]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	cytosol [GO:0005829]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]	1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; bicarbonate binding [GO:0071890]
d3ktla2_d3zmka2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	transferase activity [GO:0016740]
d3ktlb1_d4pgta2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3ktlb2_d2oacb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]
d3ktlb2_d2pera2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; intracellular [GO:0005622]; nucleus [GO:0005634]; chloride channel activity [GO:0005254]; glutathione peroxidase activity [GO:0004602]; voltage-gated ion channel activity [GO:0005244]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of binding [GO:0051099]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of binding [GO:0051099]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; intracellular [GO:0005622]; nucleus [GO:0005634]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	chloride channel activity [GO:0005254]; glutathione peroxidase activity [GO:0004602]; voltage-gated ion channel activity [GO:0005244]
d3ku6a1_d4n5zq1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3kudb__d5chwi2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3kuna__d1myma___1	Metazoa	Metazoa	Annelida	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3kuna__d2d2md___1	Metazoa	Metazoa	Annelida	Annelida	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3kuyb__d5b2ie___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3kuyd__d1p3pe___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3kuye__d5b0yf___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3kuye__d5g49b___1	Metazoa	Viridiplantae	Chordata	Streptophyta	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]; transcription coregulator activity [GO:0003712]; abscisic acid-activated signaling pathway [GO:0009738]; gibberellic acid mediated signaling pathway [GO:0009740]; long-day photoperiodism, flowering [GO:0048574]; positive regulation of photomorphogenesis [GO:2000306]; regulation of seed germination [GO:0010029]		abscisic acid-activated signaling pathway [GO:0009738]; gibberellic acid mediated signaling pathway [GO:0009740]; long-day photoperiodism, flowering [GO:0048574]; positive regulation of photomorphogenesis [GO:2000306]; regulation of seed germination [GO:0010029]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]; transcription coregulator activity [GO:0003712]
d3kuyf__d4g92b___1	Metazoa	Fungi	Chordata	Ascomycota	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	CCAAT-binding factor complex [GO:0016602]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome positioning [GO:0016584]; regulation of carbohydrate metabolic process [GO:0006109]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]		negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome positioning [GO:0016584]; regulation of carbohydrate metabolic process [GO:0006109]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	CCAAT-binding factor complex [GO:0016602]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; protein heterodimerization activity [GO:0046982]; sequence-specific DNA binding [GO:0043565]
d3kuza1_d3prpd___1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116]; semaphorin receptor activity [GO:0017154]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	ribosome [GO:0005840]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cell adhesion [GO:0007155]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	translation [GO:0006412]	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116]	ribosome [GO:0005840]	semaphorin receptor activity [GO:0017154]; signaling receptor binding [GO:0005102]	structural constituent of ribosome [GO:0003735]
d3kv2b__d4qa2b1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]; chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	chromatin assembly or disassembly [GO:0006333]; chromatin organization [GO:0006325]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	histone deacetylase activity [GO:0004407]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; transcription factor binding [GO:0008134]
d3kvfb__d2rpqa1__1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; adult walking behavior [GO:0007628]; axon target recognition [GO:0007412]; axonal transport of mitochondrion [GO:0019896]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	adult walking behavior [GO:0007628]; axonal transport of mitochondrion [GO:0019896]; axon target recognition [GO:0007412]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein sumoylation [GO:0016925]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]	RNA binding [GO:0003723]; SUMO transferase activity [GO:0019789]; transcription corepressor binding [GO:0001222]; ubiquitin protein ligase binding [GO:0031625]
d3kvsa__d5b13a___1			Rhodophyta	Rhodophyta	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]		
d3kw9a__d4mm3b2__1	Metazoa		Chordata		endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3kwca__d4m9cb___1			Cyanobacteria	Proteobacteria	metal ion binding [GO:0046872]	transferase activity, transferring acyl groups [GO:0016746]					metal ion binding [GO:0046872]	transferase activity, transferring acyl groups [GO:0016746]
d3kwhb1_d6b1eb1__1		Metazoa		Chordata		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3kwnb1_d1qold___1						host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; modulation by virus of host protein ubiquitination [GO:0039648]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host translation initiation factor activity [GO:0039611]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasm [GO:0030430]; host cell cytoplasmic vesicle membrane [GO:0044162]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; ISG15-specific protease activity [GO:0019785]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3kwnb1_d3pbha___1		Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]		cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]
d3kwwb__d1rurl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3kwxa2_d4lpcc3__1	Fungi		Ascomycota	Proteobacteria	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]	cytosol [GO:0005829]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3kx3b__d4uhlf1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]; cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]
d3kx4a__d2frza___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3kx4a__d4ruif1__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d3kx5a__d1ehga___1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]			cytoplasm [GO:0005737]		aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3kx5a__d4uaxa1__1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; cholesterol catabolic process [GO:0006707]		cholesterol catabolic process [GO:0006707]	cytoplasm [GO:0005737]		aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3kx5b__d3zpib___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]		macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]		aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3kx9c__d3pvrc1__1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]	cytosol [GO:0005829]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]	
d3kx9g__d3hx2b___1			Euryarchaeota		cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]	
d3kx9h__d2cf7e___1			Euryarchaeota	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d3kx9i__d4n83a___1			Euryarchaeota	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3kx9k__d4toda___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3kx9l__d4toeo___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3kx9n__d5ww7a___1			Euryarchaeota	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3kx9o__d4p1ca___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	toluene catabolic process [GO:0042203]	cell [GO:0005623]		ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d3kx9q__d4to9m___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3kx9s__d3bvee1__1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d3kx9w__d1oq7b___1		Viridiplantae	Euryarchaeota	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]	chloroplast [GO:0009507]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d3kx9x__d1rsrb___1			Euryarchaeota	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3kxdb1_d1b3ba1__1			Euryarchaeota	Thermotogae	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	potassium ion transport [GO:0006813]	cellular amino acid metabolic process [GO:0006520]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d3kxoa1_d2h19a___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]
d3kxob2_d5an1d2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione transferase activity [GO:0004364]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d3kxsa__d1qgtb___1					host cell cytoplasm [GO:0030430]; T=4 icosahedral viral capsid [GO:0039619]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; pathogenesis [GO:0009405]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	host cell cytoplasm [GO:0030430]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; DNA binding [GO:0003677]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; pathogenesis [GO:0009405]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; pathogenesis [GO:0009405]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; pathogenesis [GO:0009405]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	host cell cytoplasm [GO:0030430]; T=4 icosahedral viral capsid [GO:0039619]	host cell cytoplasm [GO:0030430]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d3kxsb__d5wreb___1					host cell cytoplasm [GO:0030430]; T=4 icosahedral viral capsid [GO:0039619]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; pathogenesis [GO:0009405]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	host cell cytoplasm [GO:0030430]; T=4 icosahedral viral capsid [GO:0039619]; DNA binding [GO:0003677]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; pathogenesis [GO:0009405]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; pathogenesis [GO:0009405]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; pathogenesis [GO:0009405]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	host cell cytoplasm [GO:0030430]; T=4 icosahedral viral capsid [GO:0039619]	host cell cytoplasm [GO:0030430]; T=4 icosahedral viral capsid [GO:0039619]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	DNA binding [GO:0003677]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d3kycd__d5dpwo___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; nucleolus [GO:0005730]; metal ion binding [GO:0046872]; autophagy [GO:0006914]; intracellular signal transduction [GO:0035556]; lysosome localization [GO:0032418]; positive regulation of bone resorption [GO:0045780]; positive regulation of ruffle assembly [GO:1900029]; protein transport [GO:0015031]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	autophagy [GO:0006914]; intracellular signal transduction [GO:0035556]; lysosome localization [GO:0032418]; positive regulation of bone resorption [GO:0045780]; positive regulation of ruffle assembly [GO:1900029]; protein transport [GO:0015031]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; nucleolus [GO:0005730]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]	metal ion binding [GO:0046872]
d3kyga1_d1ywua1__1			Proteobacteria	Proteobacteria	bacterial-type flagellum basal body [GO:0009425]; cofactor binding [GO:0048037]; cyclic-di-GMP binding [GO:0035438]	cyclic-di-GMP binding [GO:0035438]; second-messenger-mediated signaling [GO:0019932]		second-messenger-mediated signaling [GO:0019932]	bacterial-type flagellum basal body [GO:0009425]		cofactor binding [GO:0048037]; cyclic-di-GMP binding [GO:0035438]	cyclic-di-GMP binding [GO:0035438]
d3kyga2_d2rdea2__1			Proteobacteria	Proteobacteria	bacterial-type flagellum basal body [GO:0009425]; cofactor binding [GO:0048037]; cyclic-di-GMP binding [GO:0035438]	cofactor binding [GO:0048037]; cyclic-di-GMP binding [GO:0035438]			bacterial-type flagellum basal body [GO:0009425]		cofactor binding [GO:0048037]; cyclic-di-GMP binding [GO:0035438]	cofactor binding [GO:0048037]; cyclic-di-GMP binding [GO:0035438]
d3kyma1_d1ncbh2__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3kymc1_d1cbvl2__1		Metazoa		Chordata		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d3kymc1_d5gryg2__1												
d3kymg1_d4ened1__1				Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3kymk1_d1clol1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3kymm2_d1cfqb1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3kymo2_d3kprj2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3kynb1_d5x2nk2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; G protein-coupled receptor activity [GO:0004930]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	G protein-coupled receptor activity [GO:0004930]
d3kyob1_d1qblh1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3kyod1_d1op3h1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3kz1b1_d2dfkc1__1	Metazoa	Metazoa	Chordata	Chordata	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]	apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]
d3kz7a__d2xp4a2__1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]		cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]
d3kzka1_d4jqoa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d3kzoa1_d2aira2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d3kzua1_d1m1mb2__1			Proteobacteria	Actinobacteria	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		cytoplasm [GO:0005737]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d3kzua1_d1xesb1__1		Viridiplantae	Proteobacteria	Streptophyta	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]	biosynthetic process [GO:0009058]		cytoplasm [GO:0005737]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	pinosylvin synthase activity [GO:0050198]
d3kzua2_d4xl3b1__1			Proteobacteria	Firmicutes	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	acetyl-CoA C-acetyltransferase activity [GO:0003985]; N-acetylornithine carbamoyltransferase activity [GO:0043857]	fatty acid biosynthetic process [GO:0006633]				beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	acetyl-CoA C-acetyltransferase activity [GO:0003985]; N-acetylornithine carbamoyltransferase activity [GO:0043857]
d3kzuc2_d1m3za1__1			Proteobacteria	Proteobacteria	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3l06a1_d2a0fc2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d3l07a1_d1euzb2__1			Proteobacteria	Euryarchaeota	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cellular amino acid metabolic process [GO:0006520]			methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d3l07a2_d1f12b2__1		Metazoa	Proteobacteria	Chordata	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; positive regulation of cold-induced thermogenesis [GO:0120162]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d3l07b2_d3pjeb___1			Proteobacteria	Proteobacteria	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]; membrane [GO:0016020]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]
d3l0ca__d4nv0b___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; dephosphorylation [GO:0016311]; guanosine-containing compound catabolic process [GO:1901069]; nucleotide metabolic process [GO:0009117]; ribonucleoside monophosphate catabolic process [GO:0009158]	negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]	dephosphorylation [GO:0016311]; guanosine-containing compound catabolic process [GO:1901069]; nucleotide metabolic process [GO:0009117]; ribonucleoside monophosphate catabolic process [GO:0009158]	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]	5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]
d3l0gb1_d1qpne2__1			Proteobacteria	Actinobacteria	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d3l0gb2_d1qpqc1__1			Proteobacteria	Actinobacteria	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d3l0gc1_d5huob1__1			Proteobacteria	Firmicutes	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]			nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d3l0ha1_d1xwkc2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d3l0ha1_d3sbch___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]; identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]; cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]
d3l0hb1_d5g1kb2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	periplasmic space [GO:0042597]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	periplasmic space [GO:0042597]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d3l0hb2_d2wjua2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d3l0hb2_d4g9ha2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	transferase activity [GO:0016740]
d3l0ob2_d1wb1c5__1			Thermotogae		ATP binding [GO:0005524]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]		DNA-templated transcription, termination [GO:0006353]				ATP binding [GO:0005524]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]	
d3l0ra1_d3k9mc___1	Metazoa	Metazoa	Arthropoda	Chordata	cysteine-type endopeptidase inhibitor activity [GO:0004869]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]		cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]	cysteine-type endopeptidase inhibitor activity [GO:0004869]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]
d3l0rb1_d4n6ma___1	Metazoa	Metazoa	Arthropoda	Chordata	cysteine-type endopeptidase inhibitor activity [GO:0004869]	cornified envelope [GO:0001533]; extracellular exosome [GO:0070062]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; anatomical structure morphogenesis [GO:0009653]; epidermis development [GO:0008544]		anatomical structure morphogenesis [GO:0009653]; epidermis development [GO:0008544]		cornified envelope [GO:0001533]; extracellular exosome [GO:0070062]	cysteine-type endopeptidase inhibitor activity [GO:0004869]	cysteine-type endopeptidase inhibitor activity [GO:0004869]
d3l0rb1_d4n6v5___1	Metazoa	Metazoa	Arthropoda	Chordata	cysteine-type endopeptidase inhibitor activity [GO:0004869]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; protease binding [GO:0002020]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]		adult locomotory behavior [GO:0008344]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleolus [GO:0005730]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	cysteine-type endopeptidase inhibitor activity [GO:0004869]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; protease binding [GO:0002020]; RNA binding [GO:0003723]
d3l0wa1_d6amqb1__1	Fungi		Ascomycota	Proteobacteria	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA replication [GO:0006260]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	DNA replication [GO:0006260]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	cytoplasm [GO:0005737]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d3l10a1_d1vyjg2__1	Fungi	Metazoa	Ascomycota	Chordata	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d3l10a1_d4mjpb2__1	Fungi		Ascomycota	Proteobacteria	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3l14a__d5fl5c___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3l18a1_d1izyb___1			Euryarchaeota	Proteobacteria	peptidase activity [GO:0008233]	cytosol [GO:0005829]; glyoxalase III activity [GO:0019172]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; protein deglycase activity [GO:0036524]; thiolester hydrolase activity [GO:0016790]; zinc ion binding [GO:0008270]; DNA repair [GO:0006281]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to acidic pH [GO:0010447]; response to methylglyoxal [GO:0051595]; RNA repair [GO:0042245]		DNA repair [GO:0006281]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; protein deglycosylation [GO:0006517]; protein repair [GO:0030091]; response to acidic pH [GO:0010447]; response to methylglyoxal [GO:0051595]; RNA repair [GO:0042245]		cytosol [GO:0005829]	peptidase activity [GO:0008233]	glyoxalase III activity [GO:0019172]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; protein deglycase activity [GO:0036524]; thiolester hydrolase activity [GO:0016790]; zinc ion binding [GO:0008270]
d3l18a1_d4k2hd1__1			Euryarchaeota	Proteobacteria	peptidase activity [GO:0008233]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; peptidase activity [GO:0008233]; protein deglycase activity [GO:0036524]; guanine deglycation, glyoxal removal [GO:0106046]; protein deglycation, glyoxal removal [GO:0036529]		guanine deglycation, glyoxal removal [GO:0106046]; protein deglycation, glyoxal removal [GO:0036529]		cytosol [GO:0005829]	peptidase activity [GO:0008233]	metal ion binding [GO:0046872]; peptidase activity [GO:0008233]; protein deglycase activity [GO:0036524]
d3l1ol1_d3cx5j___1		Fungi		Ascomycota		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3l1tb__d2j7an___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]; anaerobic electron transport chain [GO:0019645]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; denitrification pathway [GO:0019333]; oxidation-reduction process [GO:0055114]	anaerobic electron transport chain [GO:0019645]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]	heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3l1ya1_d1z5sa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]; ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular protein modification process [GO:0006464]; chromosome segregation [GO:0007059]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of intracellular steroid hormone receptor signaling pathway [GO:0033145]; positive regulation of SUMO transferase activity [GO:1903755]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of signaling receptor activity [GO:0010469]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; sumoylated E2 ligase complex [GO:1990356]; synapse [GO:0045202]; synaptonemal complex [GO:0000795]; transferase complex [GO:1990234]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	ATP binding [GO:0005524]; bHLH transcription factor binding [GO:0043425]; enzyme binding [GO:0019899]; HLH domain binding [GO:0043398]; protein C-terminus binding [GO:0008022]; RING-like zinc finger domain binding [GO:0071535]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; SUMO conjugating enzyme activity [GO:0061656]; SUMO transferase activity [GO:0019789]; transcription factor binding [GO:0008134]; ubiquitin-protein transferase activity [GO:0004842]
d3l1za1_d4dhjn___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; apoptotic process [GO:0006915]; BMP signaling pathway [GO:0030509]; cellular protein modification process [GO:0006464]; DNA repair [GO:0006281]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of protein targeting to mitochondrion [GO:1903955]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apoptotic process [GO:0006915]; BMP signaling pathway [GO:0030509]; cellular protein modification process [GO:0006464]; DNA repair [GO:0006281]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of protein targeting to mitochondrion [GO:1903955]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d3l27a__d3l26b___1			Negarnaviricota	Negarnaviricota	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; evasion or tolerance by virus of host immune response [GO:0030683]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of protein sumoylation [GO:0033235]; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II [GO:0039505]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host IKBKE activity [GO:0039724]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host type I interferon production [GO:0039501]; suppression of host defenses [GO:0044414]	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; evasion or tolerance by virus of host immune response [GO:0030683]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of protein sumoylation [GO:0033235]; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II [GO:0039505]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host IKBKE activity [GO:0039724]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host type I interferon production [GO:0039501]; suppression of host defenses [GO:0044414]	evasion or tolerance by virus of host immune response [GO:0030683]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of protein sumoylation [GO:0033235]; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II [GO:0039505]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host IKBKE activity [GO:0039724]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host type I interferon production [GO:0039501]; suppression of host defenses [GO:0044414]	evasion or tolerance by virus of host immune response [GO:0030683]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of protein sumoylation [GO:0033235]; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II [GO:0039505]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host IKBKE activity [GO:0039724]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host type I interferon production [GO:0039501]; suppression of host defenses [GO:0044414]	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3l27c__d4ibea___1			Negarnaviricota	Negarnaviricota	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; evasion or tolerance by virus of host immune response [GO:0030683]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of protein sumoylation [GO:0033235]; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II [GO:0039505]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host IKBKE activity [GO:0039724]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host type I interferon production [GO:0039501]; suppression of host defenses [GO:0044414]	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; evasion or tolerance by virus of host immune response [GO:0030683]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of protein sumoylation [GO:0033235]; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II [GO:0039505]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host IKBKE activity [GO:0039724]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host type I interferon production [GO:0039501]; suppression of host defenses [GO:0044414]	evasion or tolerance by virus of host immune response [GO:0030683]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of protein sumoylation [GO:0033235]; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II [GO:0039505]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host IKBKE activity [GO:0039724]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host type I interferon production [GO:0039501]; suppression of host defenses [GO:0044414]	evasion or tolerance by virus of host immune response [GO:0030683]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of protein sumoylation [GO:0033235]; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II [GO:0039505]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host IKBKE activity [GO:0039724]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host type I interferon production [GO:0039501]; suppression of host defenses [GO:0044414]	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3l29b1_d4ibdb___1			Negarnaviricota	Negarnaviricota	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; evasion or tolerance by virus of host immune response [GO:0030683]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of protein sumoylation [GO:0033235]; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II [GO:0039505]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host IKBKE activity [GO:0039724]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host type I interferon production [GO:0039501]; suppression of host defenses [GO:0044414]	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; evasion or tolerance by virus of host immune response [GO:0030683]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of protein sumoylation [GO:0033235]; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II [GO:0039505]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host IKBKE activity [GO:0039724]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host type I interferon production [GO:0039501]; suppression of host defenses [GO:0044414]	evasion or tolerance by virus of host immune response [GO:0030683]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of protein sumoylation [GO:0033235]; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II [GO:0039505]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host IKBKE activity [GO:0039724]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host type I interferon production [GO:0039501]; suppression of host defenses [GO:0044414]	evasion or tolerance by virus of host immune response [GO:0030683]; negative regulation of gene expression [GO:0010629]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of protein sumoylation [GO:0033235]; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II [GO:0039505]; suppression by virus of host cytokine production [GO:0046775]; suppression by virus of host IKBKE activity [GO:0039724]; suppression by virus of host IRF7 activity [GO:0039557]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host TBK1 activity [GO:0039723]; suppression by virus of host toll-like receptor signaling pathway [GO:0039722]; suppression by virus of host type I interferon production [GO:0039501]; suppression of host defenses [GO:0044414]	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]	host cell cytoplasm [GO:0030430]; viral nucleocapsid [GO:0019013]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3l2da1_d1vrpa1__1	Metazoa	Metazoa	Annelida	Chordata	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3l2da2_d1f52k2__1	Metazoa		Annelida	Proteobacteria	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	phosphocreatine biosynthetic process [GO:0046314]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d3l2db1_d3b6rb1__1	Metazoa	Metazoa	Annelida	Chordata	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]	phosphocreatine biosynthetic process [GO:0046314]	cellular chloride ion homeostasis [GO:0030644]; cerebellum development [GO:0021549]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]; substantia nigra development [GO:0021762]		cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]
d3l2db1_d5j9aa1__1	Metazoa	Metazoa	Annelida	Arthropoda	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3l2dc1_d3m10b1__1	Metazoa	Metazoa	Annelida	Arthropoda	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3l2dc2_d1htqv2__1	Metazoa		Annelida	Actinobacteria	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	phosphocreatine biosynthetic process [GO:0046314]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3l2dd1_d1m80a3__1	Metazoa		Annelida		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]		phosphocreatine biosynthetic process [GO:0046314]				ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	
d3l2dd2_d1qk1f2__1	Metazoa	Metazoa	Annelida	Chordata	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]	creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3l2ea2_d1p52a2__1	Metazoa	Metazoa	Annelida	Arthropoda	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	phosphocreatine biosynthetic process [GO:0046314]	phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3l2fc1_d1qh4b1__1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]		ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]		cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]
d3l2fc2_d1htoc2__1				Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3l2fd1_d4z9me1__1		Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; phosphocreatine biosynthetic process [GO:0046314]		creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3l2fd2_d4lnfh2__1				Firmicutes		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]		cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d3l2fe2_d1sd0a2__1		Metazoa		Arthropoda		cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]		arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3l2fg1_d1qk1c1__1		Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3l2fh1_d1crkb1__1		Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; phosphocreatine biosynthetic process [GO:0046314]		phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3l2fi2_d4acfe2__1				Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3l2fl1_d4bhla1__1		Metazoa		Arthropoda		arginine binding [GO:0034618]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; dTDP metabolic process [GO:0046072]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		dTDP metabolic process [GO:0046072]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]				arginine binding [GO:0034618]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3l2fm1_d1qk1g1__1		Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3l2fn1_d1crka1__1		Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; phosphocreatine biosynthetic process [GO:0046314]		phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3l2fq1_d1qk1e1__1		Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3l2fr2_d1f52f2__1				Proteobacteria		cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d3l2ga2_d1u6ra2__1		Metazoa		Chordata		extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]		phosphocreatine biosynthetic process [GO:0046314]; response to heat [GO:0009408]		extracellular space [GO:0005615]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3l2gb1_d1qk1b1__1		Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3l2gb1_d4bg4a1__1		Metazoa		Arthropoda		arginine binding [GO:0034618]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; dTDP metabolic process [GO:0046072]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		dTDP metabolic process [GO:0046072]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]				arginine binding [GO:0034618]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3l2ge2_d1qh4b2__1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]; ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]		ATP biosynthetic process [GO:0006754]; phosphocreatine biosynthetic process [GO:0046314]		cytosol [GO:0005829]; extracellular membrane-bounded organelle [GO:0065010]; extracellular space [GO:0005615]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; ubiquitin protein ligase binding [GO:0031625]
d3l2gf1_d1crkc1__1		Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; phosphocreatine biosynthetic process [GO:0046314]		phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3l2gf2_d1fpye2__1				Proteobacteria		cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d3l2gh1_d4gvya1__1		Metazoa		Arthropoda		cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]		arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3l2gh2_d2dqnb2__1				Firmicutes		ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]; regulation of translational fidelity [GO:0006450]; translation [GO:0006412]		regulation of translational fidelity [GO:0006450]; translation [GO:0006412]				ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]
d3l2gj2_d1htov2__1				Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3l2gj2_d4lnie2__1				Firmicutes		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]		cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d3l2gk2_d4gvza2__1		Metazoa		Arthropoda		cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]		arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3l2gm1_d1qk1f1__1		Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3l2go2_d1fpyi2__1				Proteobacteria		cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d3l2gp1_d1rl9a1__1		Metazoa		Arthropoda		cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]		arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3l2la1_d1e56b___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	extracellular space [GO:0005615]	chloroplast [GO:0009507]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]
d3l2la2_d3edkb3__1	Metazoa		Chordata	Bacteroidetes	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	cyclomaltodextrinase activity [GO:0047798]; metal ion binding [GO:0046872]
d3l2ma1_d5i3da___1	Metazoa		Chordata	Crenarchaeota	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]
d3l2ma2_d2wspa2__1	Metazoa		Chordata	Thermotogae	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate catabolic process [GO:0016052]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	extracellular space [GO:0005615]	lysosome [GO:0005764]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-L-fucosidase activity [GO:0004560]
d3l2xa__d5f9xa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3l2ya__d1vald___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3l2yd__d1qh6b___1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	endo-1,4-beta-xylanase activity [GO:0031176]
d3l2yn__d4p9xa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3l2yo__d4galb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	carbohydrate binding [GO:0030246]
d3l2yp__d4ovwb___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	cellulase activity [GO:0008810]
d3l2yq__d1lgnd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d3l2yq__d1loe.2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	mannose binding [GO:0005537]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	mannose binding [GO:0005537]
d3l2ys__d1lgnc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d3l33b__d2fwwb___1	Metazoa	Metazoa	Chordata	Chordata	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid-beta clearance [GO:1900221]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	proteolysis [GO:0006508]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi lumen [GO:0005796]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]	collagen-containing extracellular matrix [GO:0062023]; extracellular space [GO:0005615]	acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3l33c__d1n1l.1__1	Metazoa		Chordata		amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid-beta clearance [GO:1900221]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; lymphocyte aggregation [GO:0071593]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host protein transport [GO:0044833]; modulation by virus of host transcription [GO:0019056]; negative regulation by symbiont of host defense-related protein level [GO:0033663]; negative regulation by symbiont of host protein levels [GO:1990214]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of ATPase activity [GO:0032780]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell death [GO:0060548]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of execution phase of apoptosis [GO:1900118]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein secretion [GO:0050709]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of RNA interference [GO:1900369]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 7 signaling pathway [GO:0034156]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive regulation by symbiont of host transcription [GO:1990216]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of proteolysis [GO:0045862]; positive regulation of secretion [GO:0051047]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of viral process [GO:0048524]; protein complex oligomerization [GO:0051259]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; suppression by virus of host apoptotic process [GO:0019050]; suppression by virus of host intracellular interferon activity [GO:0046774]; suppression by virus of host IRF9 activity [GO:0039560]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host protein phosphorylation [GO:0039613]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host transcription [GO:0039653]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]; viral budding from ER membrane [GO:0046762]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi lumen [GO:0005796]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]	cytoplasmic viral factory [GO:0039714]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi apparatus [GO:0044177]; host cell lipid droplet [GO:0044186]; host cell membrane [GO:0033644]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; host intracellular organelle [GO:0033647]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]	ATPase activity [GO:0016887]; ATPase regulator activity [GO:0060590]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DEAD/H-box RNA helicase binding [GO:0017151]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; keratin filament binding [GO:1990254]; kinase binding [GO:0019900]; MHC class I protein binding [GO:0042288]; p53 binding [GO:0002039]; peptidase activity [GO:0008233]; protein phosphatase binding [GO:0019903]; Rab GTPase binding [GO:0017137]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; scavenger receptor binding [GO:0005124]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; STAT family protein binding [GO:0097677]; structural molecule activity [GO:0005198]; Toll-like receptor 2 binding [GO:0035663]; transcription factor binding [GO:0008134]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]
d3l3ca__d3bs9b___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; negative regulation of cytokine biosynthetic process [GO:0042036]; negative regulation of translation [GO:0017148]; positive regulation of epithelial cell apoptotic process [GO:1904037]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of mRNA splicing, via spliceosome [GO:0048024]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; negative regulation of cytokine biosynthetic process [GO:0042036]; negative regulation of translation [GO:0017148]; positive regulation of epithelial cell apoptotic process [GO:1904037]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of mRNA splicing, via spliceosome [GO:0048024]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear stress granule [GO:0097165]; nucleoplasm [GO:0005654]; ribonucleoprotein complex [GO:1990904]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	mRNA 3'-UTR AU-rich region binding [GO:0035925]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]
d3l3db__d3wifb1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3l3td__d4yoib___1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; tertiary granule lumen [GO:1904724]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; antimicrobial humoral response [GO:0019730]; cobalamin metabolic process [GO:0009235]; digestion [GO:0007586]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	antimicrobial humoral response [GO:0019730]; cobalamin metabolic process [GO:0009235]; digestion [GO:0007586]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; tertiary granule lumen [GO:1904724]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3l49a1_d1jwlc___1			Proteobacteria	Proteobacteria		cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]		negative regulation of transcription, DNA-templated [GO:0045892]		cytosol [GO:0005829]		bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]
d3l49c1_d4yp9b1__1			Proteobacteria	Proteobacteria		periplasmic space [GO:0042597]				periplasmic space [GO:0042597]		
d3l49d1_d1jh9a2__1			Proteobacteria	Proteobacteria		cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]; negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]		negative regulation of purine nucleotide biosynthetic process [GO:1900372]; negative regulation of transcription, DNA-templated [GO:0045892]; purine nucleotide biosynthetic process [GO:0006164]		cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription repressor activity [GO:0001217]; guanine binding [GO:0002057]
d3l4fd1_d3khfb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; ionotropic glutamate receptor complex [GO:0008328]; neuron projection [GO:0043005]; neuron spine [GO:0044309]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; ankyrin repeat binding [GO:0071532]; GKAP/Homer scaffold activity [GO:0030160]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; protein C-terminus binding [GO:0008022]; protein-containing complex binding [GO:0044877]; receptor signaling complex adaptor activity [GO:0030159]; scaffold protein binding [GO:0097110]; SH3 domain binding [GO:0017124]; somatostatin receptor binding [GO:0031877]; adult behavior [GO:0030534]; associative learning [GO:0008306]; brain morphogenesis [GO:0048854]; cytoskeletal anchoring at plasma membrane [GO:0007016]; dendritic spine morphogenesis [GO:0060997]; determination of affect [GO:0050894]; habituation [GO:0046959]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; negative regulation of actin filament bundle assembly [GO:0032232]; neuromuscular process controlling balance [GO:0050885]; olfactory behavior [GO:0042048]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density assembly [GO:0097107]; protein localization to synapse [GO:0035418]; protein-containing complex assembly [GO:0065003]; regulation of AMPA receptor activity [GO:2000311]; righting reflex [GO:0060013]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; synaptic growth at neuromuscular junction [GO:0051124]; vocalization behavior [GO:0071625]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]	adult behavior [GO:0030534]; associative learning [GO:0008306]; brain morphogenesis [GO:0048854]; cytoskeletal anchoring at plasma membrane [GO:0007016]; dendritic spine morphogenesis [GO:0060997]; determination of affect [GO:0050894]; habituation [GO:0046959]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; negative regulation of actin filament bundle assembly [GO:0032232]; neuromuscular process controlling balance [GO:0050885]; olfactory behavior [GO:0042048]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density assembly [GO:0097107]; protein-containing complex assembly [GO:0065003]; protein localization to synapse [GO:0035418]; regulation of AMPA receptor activity [GO:2000311]; righting reflex [GO:0060013]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; synaptic growth at neuromuscular junction [GO:0051124]; vocalization behavior [GO:0071625]	cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]	cell [GO:0005623]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; glutamatergic synapse [GO:0098978]; ionotropic glutamate receptor complex [GO:0008328]; neuron projection [GO:0043005]; neuron spine [GO:0044309]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]		ankyrin repeat binding [GO:0071532]; GKAP/Homer scaffold activity [GO:0030160]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; receptor signaling complex adaptor activity [GO:0030159]; scaffold protein binding [GO:0097110]; SH3 domain binding [GO:0017124]; somatostatin receptor binding [GO:0031877]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; protein serine/threonine kinase activity [GO:0004674]
d3l4od__d1pbyb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3l4pa1_d3ns1a2__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d3l4pa2_d1xlna___1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3l4ua3_d1ea9c2__1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	cyclomaltodextrinase activity [GO:0047798]; carbohydrate metabolic process [GO:0005975]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	carbohydrate metabolic process [GO:0005975]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]		amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]	cyclomaltodextrinase activity [GO:0047798]
d3l4ua4_d1xsje1__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	carbohydrate metabolic process [GO:0005975]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]		amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d3l4va1_d1jz6c4__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	lactose catabolic process [GO:0005990]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	beta-galactosidase complex [GO:0009341]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3l4xa1_d3sepa5__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	lactose catabolic process [GO:0005990]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	beta-galactosidase complex [GO:0009341]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3l58a__d2o4ka___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3l58a__d4y57a___1	Metazoa	Fungi	Chordata	Ascomycota	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]
d3l58b__d4u7qb___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3l59a__d3sqfb___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	viral nucleocapsid [GO:0019013]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d3l59a__d5p12a___1	Metazoa	Fungi	Chordata	Ascomycota	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]		amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]
d3l5db__d3pwmb___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3l5fa__d3bgba___1	Metazoa		Chordata		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3l5ka1_d5ahxa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; pseudouridine 5'-phosphatase activity [GO:1990738]; nucleotide metabolic process [GO:0009117]; pyrimidine nucleoside salvage [GO:0043097]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	nucleotide metabolic process [GO:0009117]; pyrimidine nucleoside salvage [GO:0043097]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	magnesium ion binding [GO:0000287]; pseudouridine 5'-phosphatase activity [GO:1990738]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3l5pc1_d4grqa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d3l5q2__d3nzwc___1		Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3l5qc__d1q5qk___1				Actinobacteria		cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]		modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]		cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3l5qo__d4hrcz___1		Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3l5qr__d2fnyw___1												
d3l5qt__d1q19b2__1				Proteobacteria		asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]; antibiotic biosynthetic process [GO:0017000]; asparagine biosynthetic process [GO:0006529]		antibiotic biosynthetic process [GO:0017000]; asparagine biosynthetic process [GO:0006529]				asparagine synthase (glutamine-hydrolyzing) activity [GO:0004066]; ATP binding [GO:0005524]
d3l5qx__d3mi0z___1				Actinobacteria		cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]		modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]		threonine-type endopeptidase activity [GO:0004298]
d3l5ra__d2os5b___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]
d3l5rc1_d3kanc___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; cytokine receptor binding [GO:0005126]; D-dopachrome decarboxylase activity [GO:0033981]; dopachrome isomerase activity [GO:0004167]; phenylpyruvate tautomerase activity [GO:0050178]; melanin biosynthetic process [GO:0042438]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of tumor necrosis factor production [GO:0032760]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	melanin biosynthetic process [GO:0042438]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of tumor necrosis factor production [GO:0032760]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	cytokine receptor binding [GO:0005126]; D-dopachrome decarboxylase activity [GO:0033981]; dopachrome isomerase activity [GO:0004167]; phenylpyruvate tautomerase activity [GO:0050178]
d3l5sb1_d3mlcb___1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	
d3l5tc1_d3gadd___1	Metazoa		Chordata	Apicomplexa	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	
d3l5wa2_d4kaql1__1	Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]		cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]	
d3l5wl1_d4pgja___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3l5wl2_d1q0yh1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]	
d3l5xl1_d4d9qd1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3l5yl4_d1biha1__1		Metazoa		Arthropoda		extracellular space [GO:0005615]; innate immune response [GO:0045087]		innate immune response [GO:0045087]		extracellular space [GO:0005615]		
d3l60a__d2ihwa___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	oxidation-reduction process [GO:0055114]		cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d3l64a__d5k7oa___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3l67a__d5cpob___1			Proteobacteria	Proteobacteria	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d3l68a__d5lgza___1			Proteobacteria	Proteobacteria	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3l6ca__d1pwhd___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; D-serine ammonia-lyase activity [GO:0008721]; glycine binding [GO:0016594]; L-serine ammonia-lyase activity [GO:0003941]; magnesium ion binding [GO:0000287]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; serine racemase activity [GO:0030378]; threonine racemase activity [GO:0018114]; aging [GO:0007568]; brain development [GO:0007420]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]; gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]	aging [GO:0007568]; brain development [GO:0007420]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; response to organic cyclic compound [GO:0014070]	gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; D-serine ammonia-lyase activity [GO:0008721]; glycine binding [GO:0016594]; L-serine ammonia-lyase activity [GO:0003941]; magnesium ion binding [GO:0000287]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; serine racemase activity [GO:0030378]; threonine racemase activity [GO:0018114]	L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]
d3l6na__d4c1da___1			Bacteroidetes	Proteobacteria	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]	metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]				beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d3l6qa1_d1glly2__1			Apicomplexa	Proteobacteria	ATP binding [GO:0005524]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]		cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]		cytosol [GO:0005829]	ATP binding [GO:0005524]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d3l6qb1_d3djcl1__1			Apicomplexa	Proteobacteria	ATP binding [GO:0005524]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]		coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d3l6qb2_d5aqga2__1		Metazoa	Apicomplexa	Chordata	ATP binding [GO:0005524]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]		apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3l70a2_d1hr9d1__1	Metazoa	Fungi	Chordata	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]; aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]		aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]
d3l71a2_d1hr6a2__1	Metazoa	Fungi	Chordata	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]		protein processing involved in protein targeting to mitochondrion [GO:0006627]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3l71e2_d3cxhe1__1	Metazoa	Fungi	Chordata	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	
d3l71o2_d2a06a2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3l71r2_d4hm4a1__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	dioxygenase activity [GO:0051213]
d3l72a2_d3cxhm2__1	Metazoa	Fungi	Chordata	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	
d3l72b1_d1be3a1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3l72d1_d1m6zb2__1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3l72d1_d1sqbd1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3l72o2_d1bgya1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3l73n2_d3l74o2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d3l73o2_d1hr7g1__1	Metazoa	Fungi	Chordata	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; protein processing involved in protein targeting to mitochondrion [GO:0006627]		protein processing involved in protein targeting to mitochondrion [GO:0006627]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial processing peptidase complex [GO:0017087]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3l73o2_d3h1ho1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d3l73q1_d1kibd___1	Metazoa		Chordata	Cyanobacteria	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	thylakoid lumen [GO:0031977]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	thylakoid lumen [GO:0031977]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3l74a2_d1sqxb1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3l74b1_d1ntzb2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3l74b2_d1hr9f2__1	Metazoa	Fungi	Chordata	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]; aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]		aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; chronological cell aging [GO:0001300]; malate metabolic process [GO:0006108]; replicative cell aging [GO:0001302]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	L-malate dehydrogenase activity [GO:0030060]; mRNA binding [GO:0003729]
d3l74b2_d3h1hn2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d3l74o2_d5klvb1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3l75a2_d3h1jn1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]			integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d3l75b2_d1bccb2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3l75d1_d2ibzd1__1	Metazoa	Fungi	Chordata	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]		aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	
d3l75n1_d1qcra1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3l75q1_d5tisv___1	Metazoa		Chordata	Cyanobacteria	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	integral component of membrane [GO:0016021]; photosystem II [GO:0009523]; thylakoid membrane [GO:0042651]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; photosystem II [GO:0009523]; thylakoid membrane [GO:0042651]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]	
d3l7ea2_d2d9qb1__1		Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]		cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]
d3l7el1_d1g84a___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3l7fa1_d1n5ak___1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3l7fa2_d4x98a1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3l7fd2_d1ucbh2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3l7fl1_d4wi8a1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3l7fl1_d5bv7l1__1		Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; high-density lipoprotein particle [GO:0034364]; apolipoprotein A-I binding [GO:0034186]; phosphatidylcholine-sterol O-acyltransferase activity [GO:0004607]; cholesterol esterification [GO:0034435]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; high-density lipoprotein particle remodeling [GO:0034375]; lipoprotein biosynthetic process [GO:0042158]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylcholine metabolic process [GO:0046470]; phospholipid metabolic process [GO:0006644]; regulation of high-density lipoprotein particle assembly [GO:0090107]; reverse cholesterol transport [GO:0043691]; very-low-density lipoprotein particle remodeling [GO:0034372]		cholesterol esterification [GO:0034435]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; high-density lipoprotein particle remodeling [GO:0034375]; lipoprotein biosynthetic process [GO:0042158]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylcholine metabolic process [GO:0046470]; phospholipid metabolic process [GO:0006644]; regulation of high-density lipoprotein particle assembly [GO:0090107]; reverse cholesterol transport [GO:0043691]; very-low-density lipoprotein particle remodeling [GO:0034372]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; high-density lipoprotein particle [GO:0034364]		apolipoprotein A-I binding [GO:0034186]; phosphatidylcholine-sterol O-acyltransferase activity [GO:0004607]
d3l7fl2_d1ruph2__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3l7hc__d2b95b___1	Metazoa	Metazoa	Arthropoda	Chordata	axonemal dynein complex [GO:0005858]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; microtubule [GO:0005874]; dynein intermediate chain binding [GO:0045505]; motor activity [GO:0003774]; dendrite morphogenesis [GO:0048813]; microtubule-based movement [GO:0007018]; mushroom body development [GO:0016319]	centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; membrane [GO:0016020]; microtubule [GO:0005874]; dynein intermediate chain binding [GO:0045505]; microtubule motor activity [GO:0003777]; intraciliary transport involved in cilium assembly [GO:0035735]; microtubule-based movement [GO:0007018]; visual behavior [GO:0007632]	dendrite morphogenesis [GO:0048813]; microtubule-based movement [GO:0007018]; mushroom body development [GO:0016319]	intraciliary transport involved in cilium assembly [GO:0035735]; microtubule-based movement [GO:0007018]; visual behavior [GO:0007632]	axonemal dynein complex [GO:0005858]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; microtubule [GO:0005874]	centrosome [GO:0005813]; ciliary tip [GO:0097542]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic dynein complex [GO:0005868]; membrane [GO:0016020]; microtubule [GO:0005874]	dynein intermediate chain binding [GO:0045505]; motor activity [GO:0003774]	dynein intermediate chain binding [GO:0045505]; microtubule motor activity [GO:0003777]
d3l7qa__d2dyyd___1			Firmicutes	Euryarchaeota								
d3l7qb__d3i7ta___1			Firmicutes	Actinobacteria		plasma membrane [GO:0005886]				plasma membrane [GO:0005886]		
d3l7qe__d1comh___1			Firmicutes	Firmicutes		cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		cytoplasm [GO:0005737]		chorismate mutase activity [GO:0004106]
d3l7qf__d1x25b2__1			Firmicutes	Crenarchaeota								
d3l7qf__d3m4sf___1			Firmicutes			cytosol [GO:0005829]; mitochondrion [GO:0005739]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]		organonitrogen compound catabolic process [GO:1901565]		cytosol [GO:0005829]; mitochondrion [GO:0005739]		deaminase activity [GO:0019239]
d3l7qg__d1pf5a___1			Firmicutes	Proteobacteria		cytosol [GO:0005829]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]		organonitrogen compound catabolic process [GO:1901565]		cytosol [GO:0005829]		deaminase activity [GO:0019239]
d3l7qi__d1comi___1			Firmicutes	Firmicutes		cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		cytoplasm [GO:0005737]		chorismate mutase activity [GO:0004106]
d3l8ab__d1sf2b___1			Firmicutes	Proteobacteria	cystathionine beta-lyase activity [GO:0004121]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]	cytosol [GO:0005829]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]	biosynthetic process [GO:0009058]	arginine biosynthetic process via ornithine [GO:0042450]; gamma-aminobutyric acid catabolic process [GO:0009450]		cytosol [GO:0005829]	cystathionine beta-lyase activity [GO:0004121]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; 5-aminovalerate transaminase activity [GO:0047589]; N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]
d3l8qb2_d2cclc2__1			Firmicutes	Firmicutes	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulosome [GO:0043263]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]		cellulosome [GO:0043263]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d3l8qc1_d1nbcb___1			Firmicutes	Firmicutes	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cell wall organization [GO:0071555]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]; cell wall organization [GO:0071555]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3l8rd__d1e2ab___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d3l8rh__d1e2ac___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d3l8rh__d2lrkb___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytosol [GO:0005829]; protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity [GO:0090566]; N,N'-diacetylchitobiose import [GO:1902815]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; protein homooligomerization [GO:0051260]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	N,N'-diacetylchitobiose import [GO:1902815]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; protein homooligomerization [GO:0051260]		cytosol [GO:0005829]	metal ion binding [GO:0046872]	protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity [GO:0090566]
d3l8wa1_d3bk8a2__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d3l8za__d4v0na1__1	Metazoa	Viridiplantae	Chordata	Chlorophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	axoneme [GO:0005930]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; cilium assembly [GO:0060271]; intracellular protein transport [GO:0006886]; protein localization to cilium [GO:0061512]; vesicle-mediated transport [GO:0016192]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cilium assembly [GO:0060271]; intracellular protein transport [GO:0006886]; protein localization to cilium [GO:0061512]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	axoneme [GO:0005930]; cytoplasm [GO:0005737]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	GTP binding [GO:0005525]
d3l99a__d3o8ji___1				Proteobacteria		mitochondrial matrix [GO:0005759]; 2-methylcitrate synthase activity [GO:0050440]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]; carbohydrate metabolic process [GO:0005975]; propionate metabolic process, methylcitrate cycle [GO:0019679]; tricarboxylic acid cycle [GO:0006099]		carbohydrate metabolic process [GO:0005975]; propionate metabolic process, methylcitrate cycle [GO:0019679]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]		2-methylcitrate synthase activity [GO:0050440]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]
d3l9ea__d2aqnb___1	Metazoa		Arthropoda	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytoplasm [GO:0005737]	periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3l9ed__d3sodo___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]		activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d3l9ic__d2opob___1	Metazoa	Viridiplantae	Chordata	Streptophyta	actin filament [GO:0005884]; cell cortex [GO:0005938]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; microvillus [GO:0005902]; myosin complex [GO:0016459]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; RNA polymerase II, holoenzyme [GO:0016591]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]; actin filament-based movement [GO:0030048]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of secretion [GO:0051046]; sensory perception of sound [GO:0007605]	calcium ion binding [GO:0005509]	actin filament-based movement [GO:0030048]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of secretion [GO:0051046]; sensory perception of sound [GO:0007605]		actin filament [GO:0005884]; cell cortex [GO:0005938]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; microvillus [GO:0005902]; myosin complex [GO:0016459]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; RNA polymerase II, holoenzyme [GO:0016591]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]		actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; motor activity [GO:0003774]	calcium ion binding [GO:0005509]
d3l9ra2_d3ezjd1__1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	cell outer membrane [GO:0009279]; type II protein secretion system complex [GO:0015627]; protein secretion by the type II secretion system [GO:0015628]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	protein secretion by the type II secretion system [GO:0015628]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	cell outer membrane [GO:0009279]; type II protein secretion system complex [GO:0015627]		
d3l9ra2_d5tpwl2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	cell [GO:0005623]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; neuron projection [GO:0043005]; NMDA selective glutamate receptor complex [GO:0017146]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; ATPase binding [GO:0051117]; cell adhesion molecule binding [GO:0050839]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; glutamate receptor binding [GO:0035254]; glutamate-gated calcium ion channel activity [GO:0022849]; ionotropic glutamate receptor activity [GO:0004970]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; zinc ion binding [GO:0008270]; action potential [GO:0001508]; calcium ion transmembrane import into cytosol [GO:0097553]; cellular response to amino acid stimulus [GO:0071230]; cellular response to dsRNA [GO:0071359]; cellular response to growth factor stimulus [GO:0071363]; cellular response to lipid [GO:0071396]; cellular response to magnesium ion [GO:0071286]; cellular response to manganese ion [GO:0071287]; cellular response to zinc ion [GO:0071294]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; dendritic spine organization [GO:0097061]; excitatory postsynaptic potential [GO:0060079]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of cell death [GO:0010942]; positive regulation of excitatory postsynaptic potential [GO:2000463]; protein tetramerization [GO:0051262]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; response to amine [GO:0014075]; response to ammonium ion [GO:0060359]; response to calcium ion [GO:0051592]; response to carbohydrate [GO:0009743]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to fungicide [GO:0060992]; response to light stimulus [GO:0009416]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to organic cyclic compound [GO:0014070]; response to other organism [GO:0051707]; rhythmic process [GO:0048511]; spinal cord development [GO:0021510]; synaptic transmission, glutamatergic [GO:0035249]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	action potential [GO:0001508]; calcium ion transmembrane import into cytosol [GO:0097553]; cellular response to amino acid stimulus [GO:0071230]; cellular response to dsRNA [GO:0071359]; cellular response to growth factor stimulus [GO:0071363]; cellular response to lipid [GO:0071396]; cellular response to magnesium ion [GO:0071286]; cellular response to manganese ion [GO:0071287]; cellular response to zinc ion [GO:0071294]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; dendritic spine organization [GO:0097061]; excitatory postsynaptic potential [GO:0060079]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of cell death [GO:0010942]; positive regulation of excitatory postsynaptic potential [GO:2000463]; protein tetramerization [GO:0051262]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; response to amine [GO:0014075]; response to ammonium ion [GO:0060359]; response to calcium ion [GO:0051592]; response to carbohydrate [GO:0009743]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to fungicide [GO:0060992]; response to light stimulus [GO:0009416]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to organic cyclic compound [GO:0014070]; response to other organism [GO:0051707]; rhythmic process [GO:0048511]; spinal cord development [GO:0021510]; synaptic transmission, glutamatergic [GO:0035249]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	cell [GO:0005623]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; neuron projection [GO:0043005]; NMDA selective glutamate receptor complex [GO:0017146]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]		ATPase binding [GO:0051117]; cell adhesion molecule binding [GO:0050839]; glutamate binding [GO:0016595]; glutamate-gated calcium ion channel activity [GO:0022849]; glutamate receptor activity [GO:0008066]; glutamate receptor binding [GO:0035254]; ionotropic glutamate receptor activity [GO:0004970]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; zinc ion binding [GO:0008270]
d3l9rd__d4z7wa2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	nutrient reservoir activity [GO:0045735]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]			nutrient reservoir activity [GO:0045735]
d3l9re2_d3ciqg___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3l9re2_d4i2xc1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]		
d3l9rg2_d3k80a1__1	Metazoa		Chordata		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	kinetoplast [GO:0020023]; mitochondrial mRNA editing complex [GO:0031019]; nucleus [GO:0005634]; endonuclease activity [GO:0004519]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; RNA modification [GO:0009451]	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]	RNA modification [GO:0009451]	extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]	kinetoplast [GO:0020023]; mitochondrial mRNA editing complex [GO:0031019]; nucleus [GO:0005634]		endonuclease activity [GO:0004519]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]
d3l9yb__d2wn1b___1	Metazoa		Arthropoda		cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				cytoplasm [GO:0005737]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	
d3lahb__d5jruf___1			Firmicutes	Firmicutes	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	signal transduction [GO:0007165]	signal transduction [GO:0007165]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3lahb__d6aq3c___1			Firmicutes	Heterolobosea	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; TRAPP complex [GO:0030008]; Golgi vesicle transport [GO:0048193]	signal transduction [GO:0007165]	Golgi vesicle transport [GO:0048193]	integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; TRAPP complex [GO:0030008]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d3laib__d2j3wb1__1		Metazoa	Firmicutes	Chordata	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; TRAPP complex [GO:0030008]; ion channel binding [GO:0044325]; transcription factor binding [GO:0008134]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; regulation of transcription, DNA-templated [GO:0006355]; skeletal system development [GO:0001501]	signal transduction [GO:0007165]	endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; regulation of transcription, DNA-templated [GO:0006355]; skeletal system development [GO:0001501]	integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; TRAPP complex [GO:0030008]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	ion channel binding [GO:0044325]; transcription factor binding [GO:0008134]
d3laic__d3sj5a___1			Firmicutes	Firmicutes	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	signal transduction [GO:0007165]	signal transduction [GO:0007165]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3lasb__d4yf4a1__1			Firmicutes	Actinobacteria	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]				plasma membrane [GO:0005886]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3lb1a__d4h0mi___1	Metazoa		Annelida	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	
d3lb3b__d4lm6b___1	Metazoa		Annelida	Cryptophyta	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	phycobilisome [GO:0030089]; plastid [GO:0009536]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]; plastid [GO:0009536]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	
d3lb6a__d4cnid___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]; cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	cellular response to mechanical stimulus [GO:0071260]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; microglial cell activation [GO:0001774]; negative regulation of complement-dependent cytotoxicity [GO:1903660]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of lung ciliated cell differentiation [GO:1901247]; negative regulation of NAD(P)H oxidase activity [GO:0033861]; negative regulation of neuron death [GO:1901215]; negative regulation of transforming growth factor beta production [GO:0071635]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of connective tissue growth factor production [GO:0032723]; positive regulation of gene expression [GO:0010628]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of lung goblet cell differentiation [GO:1901251]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of pancreatic stellate cell proliferation [GO:2000231]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of proton transport [GO:0010155]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	cell [GO:0005623]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]	cytokine activity [GO:0005125]; interleukin-13 receptor binding [GO:0005144]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]
d3lbbb__d5t02e___1			Firmicutes	Proteobacteria		thiolester hydrolase activity [GO:0016790]						thiolester hydrolase activity [GO:0016790]
d3lbec__d1wlvb___1			Firmicutes	Deinococcus-Thermus		thiolester hydrolase activity [GO:0016790]						thiolester hydrolase activity [GO:0016790]
d3lbfa__d4x7vb___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]; protein repair [GO:0030091]	magnesium ion binding [GO:0000287]; O-methyltransferase activity [GO:0008171]; antibiotic biosynthetic process [GO:0017000]; methylation [GO:0032259]	protein repair [GO:0030091]	antibiotic biosynthetic process [GO:0017000]; methylation [GO:0032259]	cytoplasm [GO:0005737]		protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]	magnesium ion binding [GO:0000287]; O-methyltransferase activity [GO:0008171]
d3lbfb__d4oa5f___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]; protein repair [GO:0030091]	O-methyltransferase activity [GO:0008171]	protein repair [GO:0030091]		cytoplasm [GO:0005737]		protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]	O-methyltransferase activity [GO:0008171]
d3lbmb__d2woqa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]; porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]; heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	cytosol [GO:0005829]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	porphobilinogen synthase activity [GO:0004655]; zinc ion binding [GO:0008270]
d3lbmb__d4imca___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	N-acetylneuraminate lyase activity [GO:0008747]
d3lbsb__d1poy4___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	outer membrane-bounded periplasmic space [GO:0030288]; putrescine binding [GO:0019810]; spermidine binding [GO:0019809]; putrescine transport [GO:0015847]; spermidine transport [GO:0015848]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	putrescine transport [GO:0015847]; spermidine transport [GO:0015848]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	putrescine binding [GO:0019810]; spermidine binding [GO:0019809]
d3lc3a__d1op8f___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	extracellular region [GO:0005576]; immunological synapse [GO:0001772]; nucleus [GO:0005634]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; immune response [GO:0006955]; negative regulation of DNA binding [GO:0043392]; negative regulation of endodeoxyribonuclease activity [GO:0032078]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to bacterium [GO:0009617]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; immune response [GO:0006955]; negative regulation of DNA binding [GO:0043392]; negative regulation of endodeoxyribonuclease activity [GO:0032078]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to bacterium [GO:0009617]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; immunological synapse [GO:0001772]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]	protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]
d3lc3c__d3rxea___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3lc8b__d1l5ta___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d3lcfc__d4r53b___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3lcfd__d2rfga___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3lcga__d3lcic___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytosol [GO:0005829]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d3lcgb__d1w3tb___1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]
d3lcgd__d2yxgc___1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3lcha__d1ojxe___1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	fructose-bisphosphate aldolase activity [GO:0004332]
d3lchc__d3o1na___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	3-dehydroquinate dehydratase activity [GO:0003855]
d3lcia__d2yr1b___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	3-dehydroquinate dehydratase activity [GO:0003855]
d3lcib__d1xuza2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	catalytic activity [GO:0003824]; carbohydrate biosynthetic process [GO:0016051]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate biosynthetic process [GO:0016051]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	catalytic activity [GO:0003824]
d3lcid__d4s1fd1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	fructose metabolic process [GO:0006000]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	fructose 6-phosphate aldolase activity [GO:0097023]
d3lcid__d5o0wc___1			Proteobacteria		cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	glycolytic process [GO:0006096]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	fructose-bisphosphate aldolase activity [GO:0004332]
d3lcja__d5h7xd___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d3lcla__d4rxfb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	fructose metabolic process [GO:0006000]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	fructose 6-phosphate aldolase activity [GO:0097023]
d3lcld__d1xxxh___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3lcld__d4oe7d___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; 2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]; aldonic acid catabolic process [GO:0046176]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	aldonic acid catabolic process [GO:0046176]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]
d3lcsa__d4gj3a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NF-kappaB-inducing kinase activity [GO:0004704]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of MAPK activity [GO:0000187]; adult behavior [GO:0030534]; cell population proliferation [GO:0008283]; hippocampus development [GO:0021766]; neuron development [GO:0048666]; phosphorylation [GO:0016310]; positive regulation of dendrite development [GO:1900006]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autophosphorylation [GO:0046777]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of neuron differentiation [GO:0045664]; response to environmental enrichment [GO:0090648]; signal transduction [GO:0007165]; swimming behavior [GO:0036269]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; ATP binding [GO:0005524]; growth hormone receptor binding [GO:0005131]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713]; type 1 angiotensin receptor binding [GO:0031702]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; interleukin-27-mediated signaling pathway [GO:0070106]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; type I interferon signaling pathway [GO:0060337]	activation of MAPK activity [GO:0000187]; adult behavior [GO:0030534]; cell population proliferation [GO:0008283]; hippocampus development [GO:0021766]; neuron development [GO:0048666]; phosphorylation [GO:0016310]; positive regulation of dendrite development [GO:1900006]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autophosphorylation [GO:0046777]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of neuron differentiation [GO:0045664]; response to environmental enrichment [GO:0090648]; signal transduction [GO:0007165]; swimming behavior [GO:0036269]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytokine-mediated signaling pathway [GO:0019221]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; interleukin-27-mediated signaling pathway [GO:0070106]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; type I interferon signaling pathway [GO:0060337]	extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; NF-kappaB-inducing kinase activity [GO:0004704]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	ATP binding [GO:0005524]; growth hormone receptor binding [GO:0005131]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713]; type 1 angiotensin receptor binding [GO:0031702]
d3lcwa__d1rvgb___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	fructose-bisphosphate aldolase activity [GO:0004332]; zinc ion binding [GO:0008270]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	fructose 1,6-bisphosphate metabolic process [GO:0030388]; glycolytic process [GO:0006096]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	fructose-bisphosphate aldolase activity [GO:0004332]; zinc ion binding [GO:0008270]
d3lcwc__d3tk7a___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d3ld3a__d3i98a___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3ld5a__d3f7jb___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	methylglyoxal reductase (NADPH-dependent) activity [GO:0043892]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	methylglyoxal reductase (NADPH-dependent) activity [GO:0043892]
d3ld5a__d3q65a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d3ld6b__d1f26a___1	Metazoa	Fungi	Chordata	Ascomycota	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]; cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3ld8b1_d1y18f2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; demethylase activity [GO:0032451]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-R2 specific) [GO:0033746]; histone demethylase activity (H4-R3 specific) [GO:0033749]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidative RNA demethylase activity [GO:0035515]; P-TEFb complex binding [GO:0106140]; peptidyl-lysine 5-dioxygenase activity [GO:0070815]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; single-stranded RNA binding [GO:0003727]; transcription coactivator activity [GO:0003713]; cell surface receptor signaling pathway [GO:0007166]; erythrocyte development [GO:0048821]; heart development [GO:0007507]; histone H3-R2 demethylation [GO:0070078]; histone H4-R3 demethylation [GO:0070079]; kidney development [GO:0001822]; lung development [GO:0030324]; macrophage activation [GO:0042116]; mRNA processing [GO:0006397]; oxidative RNA demethylation [GO:0035513]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein demethylation [GO:0006482]; protein homooligomerization [GO:0051260]; recognition of apoptotic cell [GO:0043654]; regulation of mRNA splicing, via spliceosome [GO:0048024]; retina development in camera-type eye [GO:0060041]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; T cell differentiation in thymus [GO:0033077]		cell surface receptor signaling pathway [GO:0007166]; erythrocyte development [GO:0048821]; heart development [GO:0007507]; histone H3-R2 demethylation [GO:0070078]; histone H4-R3 demethylation [GO:0070079]; kidney development [GO:0001822]; lung development [GO:0030324]; macrophage activation [GO:0042116]; mRNA processing [GO:0006397]; oxidative RNA demethylation [GO:0035513]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; protein homooligomerization [GO:0051260]; recognition of apoptotic cell [GO:0043654]; regulation of mRNA splicing, via spliceosome [GO:0048024]; retina development in camera-type eye [GO:0060041]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; T cell differentiation in thymus [GO:0033077]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]		demethylase activity [GO:0032451]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-R2 specific) [GO:0033746]; histone demethylase activity (H4-R3 specific) [GO:0033749]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidative RNA demethylase activity [GO:0035515]; peptidyl-lysine 5-dioxygenase activity [GO:0070815]; protein homodimerization activity [GO:0042803]; P-TEFb complex binding [GO:0106140]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; single-stranded RNA binding [GO:0003727]; transcription coactivator activity [GO:0003713]	
d3ld8b1_d4jy4a1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; demethylase activity [GO:0032451]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-R2 specific) [GO:0033746]; histone demethylase activity (H4-R3 specific) [GO:0033749]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidative RNA demethylase activity [GO:0035515]; P-TEFb complex binding [GO:0106140]; peptidyl-lysine 5-dioxygenase activity [GO:0070815]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; single-stranded RNA binding [GO:0003727]; transcription coactivator activity [GO:0003713]; cell surface receptor signaling pathway [GO:0007166]; erythrocyte development [GO:0048821]; heart development [GO:0007507]; histone H3-R2 demethylation [GO:0070078]; histone H4-R3 demethylation [GO:0070079]; kidney development [GO:0001822]; lung development [GO:0030324]; macrophage activation [GO:0042116]; mRNA processing [GO:0006397]; oxidative RNA demethylation [GO:0035513]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein demethylation [GO:0006482]; protein homooligomerization [GO:0051260]; recognition of apoptotic cell [GO:0043654]; regulation of mRNA splicing, via spliceosome [GO:0048024]; retina development in camera-type eye [GO:0060041]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; T cell differentiation in thymus [GO:0033077]		cell surface receptor signaling pathway [GO:0007166]; erythrocyte development [GO:0048821]; heart development [GO:0007507]; histone H3-R2 demethylation [GO:0070078]; histone H4-R3 demethylation [GO:0070079]; kidney development [GO:0001822]; lung development [GO:0030324]; macrophage activation [GO:0042116]; mRNA processing [GO:0006397]; oxidative RNA demethylation [GO:0035513]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; protein homooligomerization [GO:0051260]; recognition of apoptotic cell [GO:0043654]; regulation of mRNA splicing, via spliceosome [GO:0048024]; retina development in camera-type eye [GO:0060041]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; T cell differentiation in thymus [GO:0033077]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]		demethylase activity [GO:0032451]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-R2 specific) [GO:0033746]; histone demethylase activity (H4-R3 specific) [GO:0033749]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidative RNA demethylase activity [GO:0035515]; peptidyl-lysine 5-dioxygenase activity [GO:0070815]; protein homodimerization activity [GO:0042803]; P-TEFb complex binding [GO:0106140]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; single-stranded RNA binding [GO:0003727]; transcription coactivator activity [GO:0003713]	
d3ld8b2_d4at6n1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; demethylase activity [GO:0032451]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-R2 specific) [GO:0033746]; histone demethylase activity (H4-R3 specific) [GO:0033749]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidative RNA demethylase activity [GO:0035515]; P-TEFb complex binding [GO:0106140]; peptidyl-lysine 5-dioxygenase activity [GO:0070815]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; single-stranded RNA binding [GO:0003727]; transcription coactivator activity [GO:0003713]; cell surface receptor signaling pathway [GO:0007166]; erythrocyte development [GO:0048821]; heart development [GO:0007507]; histone H3-R2 demethylation [GO:0070078]; histone H4-R3 demethylation [GO:0070079]; kidney development [GO:0001822]; lung development [GO:0030324]; macrophage activation [GO:0042116]; mRNA processing [GO:0006397]; oxidative RNA demethylation [GO:0035513]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein demethylation [GO:0006482]; protein homooligomerization [GO:0051260]; recognition of apoptotic cell [GO:0043654]; regulation of mRNA splicing, via spliceosome [GO:0048024]; retina development in camera-type eye [GO:0060041]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; T cell differentiation in thymus [GO:0033077]		cell surface receptor signaling pathway [GO:0007166]; erythrocyte development [GO:0048821]; heart development [GO:0007507]; histone H3-R2 demethylation [GO:0070078]; histone H4-R3 demethylation [GO:0070079]; kidney development [GO:0001822]; lung development [GO:0030324]; macrophage activation [GO:0042116]; mRNA processing [GO:0006397]; oxidative RNA demethylation [GO:0035513]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; protein homooligomerization [GO:0051260]; recognition of apoptotic cell [GO:0043654]; regulation of mRNA splicing, via spliceosome [GO:0048024]; retina development in camera-type eye [GO:0060041]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; T cell differentiation in thymus [GO:0033077]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]		demethylase activity [GO:0032451]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-R2 specific) [GO:0033746]; histone demethylase activity (H4-R3 specific) [GO:0033749]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidative RNA demethylase activity [GO:0035515]; peptidyl-lysine 5-dioxygenase activity [GO:0070815]; protein homodimerization activity [GO:0042803]; P-TEFb complex binding [GO:0106140]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; single-stranded RNA binding [GO:0003727]; transcription coactivator activity [GO:0003713]	
d3ldbb1_d1fveb1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; demethylase activity [GO:0032451]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-R2 specific) [GO:0033746]; histone demethylase activity (H4-R3 specific) [GO:0033749]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidative RNA demethylase activity [GO:0035515]; P-TEFb complex binding [GO:0106140]; peptidyl-lysine 5-dioxygenase activity [GO:0070815]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; single-stranded RNA binding [GO:0003727]; transcription coactivator activity [GO:0003713]; cell surface receptor signaling pathway [GO:0007166]; erythrocyte development [GO:0048821]; heart development [GO:0007507]; histone H3-R2 demethylation [GO:0070078]; histone H4-R3 demethylation [GO:0070079]; kidney development [GO:0001822]; lung development [GO:0030324]; macrophage activation [GO:0042116]; mRNA processing [GO:0006397]; oxidative RNA demethylation [GO:0035513]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein demethylation [GO:0006482]; protein homooligomerization [GO:0051260]; recognition of apoptotic cell [GO:0043654]; regulation of mRNA splicing, via spliceosome [GO:0048024]; retina development in camera-type eye [GO:0060041]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; T cell differentiation in thymus [GO:0033077]		cell surface receptor signaling pathway [GO:0007166]; erythrocyte development [GO:0048821]; heart development [GO:0007507]; histone H3-R2 demethylation [GO:0070078]; histone H4-R3 demethylation [GO:0070079]; kidney development [GO:0001822]; lung development [GO:0030324]; macrophage activation [GO:0042116]; mRNA processing [GO:0006397]; oxidative RNA demethylation [GO:0035513]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; protein homooligomerization [GO:0051260]; recognition of apoptotic cell [GO:0043654]; regulation of mRNA splicing, via spliceosome [GO:0048024]; retina development in camera-type eye [GO:0060041]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; T cell differentiation in thymus [GO:0033077]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]		demethylase activity [GO:0032451]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-R2 specific) [GO:0033746]; histone demethylase activity (H4-R3 specific) [GO:0033749]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidative RNA demethylase activity [GO:0035515]; peptidyl-lysine 5-dioxygenase activity [GO:0070815]; protein homodimerization activity [GO:0042803]; P-TEFb complex binding [GO:0106140]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; single-stranded RNA binding [GO:0003727]; transcription coactivator activity [GO:0003713]	
d3ldbb2_d4untb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]; demethylase activity [GO:0032451]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-R2 specific) [GO:0033746]; histone demethylase activity (H4-R3 specific) [GO:0033749]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidative RNA demethylase activity [GO:0035515]; P-TEFb complex binding [GO:0106140]; peptidyl-lysine 5-dioxygenase activity [GO:0070815]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; single-stranded RNA binding [GO:0003727]; transcription coactivator activity [GO:0003713]; cell surface receptor signaling pathway [GO:0007166]; erythrocyte development [GO:0048821]; heart development [GO:0007507]; histone H3-R2 demethylation [GO:0070078]; histone H4-R3 demethylation [GO:0070079]; kidney development [GO:0001822]; lung development [GO:0030324]; macrophage activation [GO:0042116]; mRNA processing [GO:0006397]; oxidative RNA demethylation [GO:0035513]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein demethylation [GO:0006482]; protein homooligomerization [GO:0051260]; recognition of apoptotic cell [GO:0043654]; regulation of mRNA splicing, via spliceosome [GO:0048024]; retina development in camera-type eye [GO:0060041]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; T cell differentiation in thymus [GO:0033077]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface receptor signaling pathway [GO:0007166]; erythrocyte development [GO:0048821]; heart development [GO:0007507]; histone H3-R2 demethylation [GO:0070078]; histone H4-R3 demethylation [GO:0070079]; kidney development [GO:0001822]; lung development [GO:0030324]; macrophage activation [GO:0042116]; mRNA processing [GO:0006397]; oxidative RNA demethylation [GO:0035513]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; protein homooligomerization [GO:0051260]; recognition of apoptotic cell [GO:0043654]; regulation of mRNA splicing, via spliceosome [GO:0048024]; retina development in camera-type eye [GO:0060041]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; T cell differentiation in thymus [GO:0033077]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ribonucleoprotein complex [GO:1990904]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	demethylase activity [GO:0032451]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-R2 specific) [GO:0033746]; histone demethylase activity (H4-R3 specific) [GO:0033749]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidative RNA demethylase activity [GO:0035515]; peptidyl-lysine 5-dioxygenase activity [GO:0070815]; protein homodimerization activity [GO:0042803]; P-TEFb complex binding [GO:0106140]; RNA binding [GO:0003723]; signaling receptor activity [GO:0038023]; single-stranded RNA binding [GO:0003727]; transcription coactivator activity [GO:0003713]	antigen binding [GO:0003823]
d3ldla2_d2qw9b2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d3ldna1_d2w40d2__1	Metazoa		Chordata	Apicomplexa	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	mitochondrion [GO:0005739]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d3ldna2_d1g99b2__1	Metazoa		Chordata	Euryarchaeota	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]
d3ldnb2_d2d0pa3__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]		ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	
d3ldob2_d1glfy1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	cytosol [GO:0005829]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d3ldza__d1szac1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA polymerase II complex binding [GO:0000993]; mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; termination of RNA polymerase II transcription [GO:0006369]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; termination of RNA polymerase II transcription, poly(A)-coupled [GO:0030846]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; termination of RNA polymerase II transcription [GO:0006369]; termination of RNA polymerase II transcription, exosome-dependent [GO:0030847]; termination of RNA polymerase II transcription, poly(A)-coupled [GO:0030846]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mRNA cleavage factor complex [GO:0005849]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	mRNA binding [GO:0003729]; RNA polymerase II complex binding [GO:0000993]
d3ldzb__d3g2vb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]
d3ldzc__d3g2ua___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]
d3ldzd__d1lf8b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]; ADP-ribosylation factor binding [GO:0030306]; ubiquitin binding [GO:0043130]; cellular protein metabolic process [GO:0044267]; endocytic recycling [GO:0032456]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; negative regulation of amyloid-beta formation [GO:1902430]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein localization to cell surface [GO:0034394]; protein localization to lysosome [GO:0061462]; regulation of protein stability [GO:0031647]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein metabolic process [GO:0044267]; endocytic recycling [GO:0032456]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; negative regulation of amyloid-beta formation [GO:1902430]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein localization to cell surface [GO:0034394]; protein localization to lysosome [GO:0061462]; regulation of protein stability [GO:0031647]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; recycling endosome membrane [GO:0055038]; trans-Golgi network [GO:0005802]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	ADP-ribosylation factor binding [GO:0030306]; ubiquitin binding [GO:0043130]
d3ldzd__d4avxa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; ESCRT-0 complex [GO:0033565]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; multivesicular body membrane [GO:0032585]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; ubiquitin-like protein ligase binding [GO:0044389]; endosomal transport [GO:0016197]; macroautophagy [GO:0016236]; membrane invagination [GO:0010324]; membrane organization [GO:0061024]; multivesicular body assembly [GO:0036258]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of gene expression [GO:0010628]; protein deubiquitination [GO:0016579]; protein localization to membrane [GO:0072657]; protein targeting to lysosome [GO:0006622]; regulation of MAP kinase activity [GO:0043405]; regulation of protein catabolic process [GO:0042176]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	endosomal transport [GO:0016197]; macroautophagy [GO:0016236]; membrane invagination [GO:0010324]; membrane organization [GO:0061024]; multivesicular body assembly [GO:0036258]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of gene expression [GO:0010628]; protein deubiquitination [GO:0016579]; protein localization to membrane [GO:0072657]; protein targeting to lysosome [GO:0006622]; regulation of MAP kinase activity [GO:0043405]; regulation of protein catabolic process [GO:0042176]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; ESCRT-0 complex [GO:0033565]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; multivesicular body membrane [GO:0032585]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; ubiquitin-like protein ligase binding [GO:0044389]
d3leaa__d1bkca___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d3leab__d4aiga___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]		actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3lega__d1jz0a3__1			Firmicutes		extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; cholesterol binding [GO:0015485]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; hemolysis in other organism [GO:0044179]		hemolysis in other organism [GO:0044179]		extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]		cholesterol binding [GO:0015485]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d3lela__d1f66g___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3lele__d1tafb___1	Metazoa	Metazoa	Chordata	Arthropoda	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleus [GO:0005634]; SAGA complex [GO:0000124]; transcription factor TFIID complex [GO:0005669]; protein heterodimerization activity [GO:0046982]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; histone H3 acetylation [GO:0043966]; ovarian follicle cell development [GO:0030707]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]		histone H3 acetylation [GO:0043966]; ovarian follicle cell development [GO:0030707]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleus [GO:0005634]; SAGA complex [GO:0000124]; transcription factor TFIID complex [GO:0005669]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	protein heterodimerization activity [GO:0046982]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3lelg__d5b33h___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3lelm__d4wnne___1	Metazoa	Fungi	Chordata	Ascomycota	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nuclear nucleosome [GO:0000788]; replication fork protection complex [GO:0031298]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin assembly or disassembly [GO:0006333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334]; postreplication repair [GO:0006301]		chromatin assembly or disassembly [GO:0006333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334]; postreplication repair [GO:0006301]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nuclear nucleosome [GO:0000788]; replication fork protection complex [GO:0031298]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3levh2_d3auve2__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]; transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]		transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]		cytoplasm [GO:0005737]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]	
d3levh2_d4gq9l2__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]; transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]		transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]		cytoplasm [GO:0005737]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]	
d3levl1_d1ngwb2__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]; transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	transcription initiation from bacterial-type RNA polymerase promoter [GO:0001123]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytoplasm [GO:0005737]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sigma factor activity [GO:0016987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3lf2b__d5i7fd___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]			metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d3lf5a__d4b8nc___1	Metazoa		Chordata		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; perinuclear region of cytoplasm [GO:0048471]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; bicarbonate transport [GO:0015701]; cell development [GO:0048468]; detection of oxygen [GO:0003032]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; insulin secretion [GO:0030073]; oxidation-reduction process [GO:0055114]; response to antibiotic [GO:0046677]; superoxide metabolic process [GO:0006801]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	bicarbonate transport [GO:0015701]; cell development [GO:0048468]; detection of oxygen [GO:0003032]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; insulin secretion [GO:0030073]; oxidation-reduction process [GO:0055114]; response to antibiotic [GO:0046677]; superoxide metabolic process [GO:0006801]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; perinuclear region of cytoplasm [GO:0048471]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3lfhc__d4tkzc___1			Firmicutes	Firmicutes	integral component of membrane [GO:0016021]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	transferase activity [GO:0016740]	
d3lfhd__d3ct6b2__1			Firmicutes	Firmicutes	integral component of membrane [GO:0016021]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; phosphoenolpyruvate-glycerone phosphotransferase activity [GO:0047324]; glycerol catabolic process [GO:0019563]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	glycerol catabolic process [GO:0019563]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	transferase activity [GO:0016740]	ATP binding [GO:0005524]; phosphoenolpyruvate-glycerone phosphotransferase activity [GO:0047324]
d3lfja1_d2jzod___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]; glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	glucose import across plasma membrane [GO:0098708]; mannose transmembrane transport [GO:0015761]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity [GO:0022870]
d3lfjb1_d1nrzb___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]
d3lfla1_d17gsb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3lflc2_d2x64b2__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	transferase activity [GO:0016740]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]	transferase activity [GO:0016740]
d3lg4a__d3dl5d1__1			Firmicutes		dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	
d3lghb2_d2p9ca3__1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	L-serine biosynthetic process [GO:0006564]	protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]
d3lgia__d1s82a___1		Metazoa	Proteobacteria	Chordata	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]	extracellular space [GO:0005615]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3lgma1_d5xztl___1		Viridiplantae	Firmicutes	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; heme catabolic process [GO:0042167]; iron import into cell [GO:0033212]	lyase activity [GO:0016829]	heme catabolic process [GO:0042167]; iron import into cell [GO:0033212]		cell [GO:0005623]; cytoplasm [GO:0005737]		heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]	lyase activity [GO:0016829]
d3lgnb1_d2zdob1__1			Firmicutes	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; heme catabolic process [GO:0042167]; iron import into cell [GO:0033212]	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; heme catabolic process [GO:0042167]; iron import into cell [GO:0033212]	heme catabolic process [GO:0042167]; iron import into cell [GO:0033212]	heme catabolic process [GO:0042167]; iron import into cell [GO:0033212]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]
d3lgpb__d4h3xb1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3lgsd__d1ouma___1	Viridiplantae		Streptophyta	Proteobacteria	cytosol [GO:0005829]; plasma membrane [GO:0005886]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; membrane [GO:0016020]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]
d3lh2k1_d1a6wl___1		Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		
d3lh2l__d5ushe2__1						integral component of membrane [GO:0016021]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]				integral component of membrane [GO:0016021]		carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3lh2n__d4tuod2__1												
d3lh4a__d3mon.8__1	Metazoa	Viridiplantae	Arthropoda	Streptophyta	extracellular region [GO:0005576]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]		negative regulation of cysteine-type endopeptidase activity [GO:2000117]		extracellular region [GO:0005576]		cysteine-type endopeptidase inhibitor activity [GO:0004869]	
d3lh6a__d5xcka___1						cytosol [GO:0005829]; endosome [GO:0005768]; retromer complex [GO:0030904]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]		intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]		cytosol [GO:0005829]; endosome [GO:0005768]; retromer complex [GO:0030904]		
d3lh6b__d4kbpc2__1		Viridiplantae		Streptophyta		extracellular region [GO:0005576]; acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]				extracellular region [GO:0005576]		acid phosphatase activity [GO:0003993]; ferric iron binding [GO:0008199]; zinc ion binding [GO:0008270]
d3lh7a__d2ahda___1				Euryarchaeota		hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]						hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3lhba__d2gknb___1	Metazoa		Chordata	Actinobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d3lhba__d3oo5a___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3lhbb__d2oifd___1	Metazoa	Viridiplantae	Chordata	Streptophyta	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]
d3lhbe__d2uumj___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3lhbg__d3brpa___1	Metazoa		Chordata	Rhodophyta	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3lhbj__d5toue___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3lhbl__d4maxc___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3lhda__d2h11b___1		Metazoa	Euryarchaeota	Chordata	tRNA (m1A) methyltransferase complex [GO:0031515]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]	cytosol [GO:0005829]; S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]; drug metabolic process [GO:0017144]; methylation [GO:0032259]; nucleobase-containing compound metabolic process [GO:0006139]		drug metabolic process [GO:0017144]; methylation [GO:0032259]; nucleobase-containing compound metabolic process [GO:0006139]	tRNA (m1A) methyltransferase complex [GO:0031515]	cytosol [GO:0005829]	tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]	S-adenosyl-L-methionine binding [GO:1904047]; thiopurine S-methyltransferase activity [GO:0008119]
d3lhtb__d4o8rh___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3lhub__d4a2sa1__1			Euryarchaeota	Crenarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	tryptophan biosynthetic process [GO:0000162]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]
d3lhva__d3ovra___1		Metazoa	Euryarchaeota	Chordata	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3lhwa__d3femf___1		Fungi	Euryarchaeota	Ascomycota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]		glutaminase complex [GO:1903600]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3lhwb__d4nu7c___1			Euryarchaeota		orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]				orotidine-5'-phosphate decarboxylase activity [GO:0004590]	
d3lhzb__d3pbwb___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3lhzb__d4adua___1			Euryarchaeota	Apicomplexa	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; pyridoxal phosphate biosynthetic process [GO:0042823]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal phosphate biosynthetic process [GO:0042823]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3li0a__d4utua1__1			Euryarchaeota	Firmicutes	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	N-acylglucosamine-6-phosphate 2-epimerase activity [GO:0047465]; N-acylmannosamine-6-phosphate 2-epimerase activity [GO:0009385]; carbohydrate metabolic process [GO:0005975]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	N-acylglucosamine-6-phosphate 2-epimerase activity [GO:0047465]; N-acylmannosamine-6-phosphate 2-epimerase activity [GO:0009385]
d3li2a1_d5cx1g___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]	metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d3li4a__d2dg1c___1	Metazoa		Mollusca	Firmicutes	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]				cytoplasm [GO:0005737]	calcium ion binding [GO:0005509]; diisopropyl-fluorophosphatase activity [GO:0047862]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3liba__d2w27a2__1			Euryarchaeota	Firmicutes	integral component of membrane [GO:0016021]; kinase activity [GO:0016301]; signal transduction [GO:0007165]		signal transduction [GO:0007165]		integral component of membrane [GO:0016021]		kinase activity [GO:0016301]	
d3libd__d3lida1__1			Euryarchaeota	Proteobacteria	integral component of membrane [GO:0016021]; kinase activity [GO:0016301]; signal transduction [GO:0007165]		signal transduction [GO:0007165]		integral component of membrane [GO:0016021]		kinase activity [GO:0016301]	
d3libf__d1ojga___1			Euryarchaeota	Proteobacteria	integral component of membrane [GO:0016021]; kinase activity [GO:0016301]; signal transduction [GO:0007165]	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; phosphorelay signal transduction system [GO:0000160]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction by protein phosphorylation [GO:0023014]	signal transduction [GO:0007165]	phosphorelay signal transduction system [GO:0000160]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction by protein phosphorylation [GO:0023014]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	kinase activity [GO:0016301]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d3libg__d1p0ze1__1			Euryarchaeota	Proteobacteria	integral component of membrane [GO:0016021]; kinase activity [GO:0016301]; signal transduction [GO:0007165]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]	signal transduction [GO:0007165]		integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	kinase activity [GO:0016301]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]
d3libh__d1p0zi1__1			Euryarchaeota	Proteobacteria	integral component of membrane [GO:0016021]; kinase activity [GO:0016301]; signal transduction [GO:0007165]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]	signal transduction [GO:0007165]		integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	kinase activity [GO:0016301]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]
d3libj__d3lida2__1			Euryarchaeota	Proteobacteria	integral component of membrane [GO:0016021]; kinase activity [GO:0016301]; signal transduction [GO:0007165]		signal transduction [GO:0007165]		integral component of membrane [GO:0016021]		kinase activity [GO:0016301]	
d3lidb1_d3libb___1			Proteobacteria	Euryarchaeota		integral component of membrane [GO:0016021]; kinase activity [GO:0016301]; signal transduction [GO:0007165]		signal transduction [GO:0007165]		integral component of membrane [GO:0016021]		kinase activity [GO:0016301]
d3lioa1_d1my6a1__1			Proteobacteria	Cyanobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3liob1_d6elkc1__1		Metazoa	Proteobacteria	Nematoda (roundworms)	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]		mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; superoxide dismutase activity [GO:0004784]
d3lipa__d1cuga___1		Fungi	Proteobacteria	Ascomycota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	cutinase activity [GO:0050525]
d3liwa__d5fcra___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]; complement activation, alternative pathway [GO:0006957]; Notch signaling pathway [GO:0007219]; response to bacterium [GO:0009617]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	complement activation, alternative pathway [GO:0006957]; Notch signaling pathway [GO:0007219]; response to bacterium [GO:0009617]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; serine-type endopeptidase activity [GO:0004252]
d3lj9b1_d1xrea1__1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]			metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3lj9b2_d4gunh2__1		Fungi	Proteobacteria	Ascomycota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ljad__d5gxqg___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3ljfa2_d4yioa2__1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ljfc1_d4l2cb1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ljfd1_d1uera1__1			Proteobacteria	Bacteroidetes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ljga1_d5o8na___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3ljoa__d3zz5a1__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3ljra1_d4zbdb2__1	Metazoa	Fungi	Chordata	Basidiomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]		glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		glutathione transferase activity [GO:0004364]	
d3ljta1_d5uwla___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d3lk0a__d4qnhr___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; small conductance calcium-activated potassium channel activity [GO:0016286]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of neuronal synaptic plasticity [GO:0048168]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of neuronal synaptic plasticity [GO:0048168]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	calmodulin binding [GO:0005516]; small conductance calcium-activated potassium channel activity [GO:0016286]
d3lk0d__d2mrda___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d3lkna1_d4ozga1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3lknb1_d5vh3b2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3lkoa2_d3sdad1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3lkob1_d4enef2__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3lkpa2_d4rdqh1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]; chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]; transepithelial chloride transport [GO:0030321]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	basolateral plasma membrane [GO:0016323]; chloride channel complex [GO:0034707]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	chloride channel activity [GO:0005254]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3lkqa1_d5bxfc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3lkqa2_d3sknb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3lkrb1_d1p6ab1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3lksa2_d5ugyl2__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]
d3lksb1_d3ay4a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	IgG binding [GO:0019864]
d3lksb1_d5fv1m___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]
d3lktn__d3hgia___1			Proteobacteria	Actinobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]; aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]
d3lkza__d4qppa___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; histone methyltransferase activity [GO:0042054]; histone methyltransferase activity (H2A-R3 specific) [GO:0070612]; histone methyltransferase activity (H3-R2 specific) [GO:0070611]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; histone-arginine N-methyltransferase activity [GO:0008469]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; base-excision repair [GO:0006284]; cellular senescence [GO:0090398]; histone H3-R2 methylation [GO:0034970]; histone methylation [GO:0016571]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; viral process [GO:0016032]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	base-excision repair [GO:0006284]; cellular senescence [GO:0090398]; histone H3-R2 methylation [GO:0034970]; histone methylation [GO:0016571]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; viral process [GO:0016032]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	chromatin binding [GO:0003682]; histone-arginine N-methyltransferase activity [GO:0008469]; histone binding [GO:0042393]; histone methyltransferase activity [GO:0042054]; histone methyltransferase activity (H2A-R3 specific) [GO:0070612]; histone methyltransferase activity (H3-R2 specific) [GO:0070611]; histone methyltransferase activity (H4-R3 specific) [GO:0044020]; protein-arginine N-methyltransferase activity [GO:0016274]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]
d3lkzb__d3b7pa___1				Apicomplexa	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; positive stranded viral RNA replication [GO:0039690]; suppression by virus of host complement activation [GO:0039573]; suppression by virus of host innate immune response [GO:0039503]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytosol [GO:0005829]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	spermidine synthase activity [GO:0004766]
d3lldb__d2flia1__1			Euryarchaeota	Firmicutes	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3lleb__d1c07a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]; clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	astrocyte activation [GO:0048143]; axonogenesis [GO:0007409]; learning or memory [GO:0007611]; memory [GO:0007613]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; phosphorylation [GO:0016310]; positive regulation of complement activation [GO:0045917]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of translation [GO:0006417]	clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase inhibitor activity [GO:0019210]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]
d3lmeb1_d1comf___1			Proteobacteria	Firmicutes		cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		cytoplasm [GO:0005737]		chorismate mutase activity [GO:0004106]
d3lmec1_d3quwa___1		Fungi	Proteobacteria	Ascomycota		cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; deaminase activity [GO:0019239]; isoleucine biosynthetic process [GO:0009097]; mitochondrial translation [GO:0032543]; organonitrogen compound catabolic process [GO:1901565]		isoleucine biosynthetic process [GO:0009097]; mitochondrial translation [GO:0032543]; organonitrogen compound catabolic process [GO:1901565]		cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		deaminase activity [GO:0019239]
d3lmee1_d1onih___1		Metazoa	Proteobacteria	Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]; deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; L-threonine catabolic process to glycine [GO:0019518]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]		brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; L-threonine catabolic process to glycine [GO:0019518]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]		deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d3lmei1_d2chsc___1			Proteobacteria	Firmicutes		cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		cytoplasm [GO:0005737]		chorismate mutase activity [GO:0004106]
d3lmjl1_d3i6kf1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ln2a__d1gb2a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3ln2a__d211la___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell cytoplasm [GO:0030430]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3ln4b__d2zswf___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3ln4b__d5e5me___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3lndc1_d5jylc___1	Metazoa	Metazoa	Chordata	Chordata	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Notch signaling pathway [GO:0007219]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Notch signaling pathway [GO:0007219]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3lnfa1_d4zmxb1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3lnfa2_d4zmwa1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3lnfb2_d5jyma1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3lnga1_d3ppea1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	bicellular tight junction [GO:0005923]; catenin complex [GO:0016342]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; fibrinogen binding [GO:0070051]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; adherens junction organization [GO:0034332]; blood vessel maturation [GO:0001955]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular calcium ion homeostasis [GO:0006874]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of angiogenesis [GO:0045766]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell migration [GO:0030335]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of establishment of cell polarity [GO:2000114]; regulation of protein phosphorylation [GO:0001932]; regulation of vascular permeability [GO:0043114]; transforming growth factor beta receptor signaling pathway [GO:0007179]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; blood vessel maturation [GO:0001955]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular calcium ion homeostasis [GO:0006874]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of angiogenesis [GO:0045766]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell migration [GO:0030335]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of gene expression [GO:0010628]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of establishment of cell polarity [GO:2000114]; regulation of protein phosphorylation [GO:0001932]; regulation of vascular permeability [GO:0043114]; transforming growth factor beta receptor signaling pathway [GO:0007179]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	bicellular tight junction [GO:0005923]; catenin complex [GO:0016342]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	beta-catenin binding [GO:0008013]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; fibrinogen binding [GO:0070051]; ion channel binding [GO:0044325]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; vascular endothelial growth factor receptor 2 binding [GO:0043184]
d3lnga2_d4zmna2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3lngb1_d3k5sb2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]
d3lnha1_d2v37a___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; mitotic cell cycle [GO:0000278]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; GABA-ergic synapse [GO:0098982]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; lipoprotein particle binding [GO:0071813]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]
d3lnha2_d4zmna1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3lnhb2_d4zmte1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3lnhb2_d5jylc___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3lnmc__d2wzta___1	Metazoa		Chordata	Actinobacteria	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	oxidoreductase activity [GO:0016491]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]		axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]		delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]	oxidoreductase activity [GO:0016491]
d3lntb__d1dkqa___1			Proteobacteria	Proteobacteria	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	outer membrane-bounded periplasmic space [GO:0030288]; 4-phytase activity [GO:0008707]; acid phosphatase activity [GO:0003993]; inositol phosphate phosphatase activity [GO:0052745]; nucleotidase activity [GO:0008252]; sugar-phosphatase activity [GO:0050308]; cellular response to anoxia [GO:0071454]; cellular response to phosphate starvation [GO:0016036]; dephosphorylation [GO:0016311]; myo-inositol hexakisphosphate dephosphorylation [GO:0033518]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cellular response to anoxia [GO:0071454]; cellular response to phosphate starvation [GO:0016036]; dephosphorylation [GO:0016311]; myo-inositol hexakisphosphate dephosphorylation [GO:0033518]		outer membrane-bounded periplasmic space [GO:0030288]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]	4-phytase activity [GO:0008707]; acid phosphatase activity [GO:0003993]; inositol phosphate phosphatase activity [GO:0052745]; nucleotidase activity [GO:0008252]; sugar-phosphatase activity [GO:0050308]
d3lnwb__d5t1oa___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; transferase activity [GO:0016740]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	cytoplasm [GO:0005737]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; protein phosphorylation [GO:0006468]; response to organonitrogen compound [GO:0010243]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; protein phosphorylation [GO:0006468]; response to organonitrogen compound [GO:0010243]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	transferase activity [GO:0016740]	kinase activity [GO:0016301]; metal ion binding [GO:0046872]; phosphoenolpyruvate-protein phosphotransferase activity [GO:0008965]
d3lnxd__d1n6fe1__1	Metazoa		Chordata	Euryarchaeota	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]; proteolysis [GO:0006508]	cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	proteolysis [GO:0006508]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]	serine-type peptidase activity [GO:0008236]
d3locc1_d5myla1__1			Proteobacteria	Actinobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding [GO:0003677]
d3locd1_d4m3da1__1			Proteobacteria	Actinobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding [GO:0003677]
d3loia__d1zrra___1	Metazoa		Chordata	Proteobacteria		acireductone dioxygenase (Ni2+-requiring) activity [GO:0010308]; acireductone dioxygenase [iron(II)-requiring] activity [GO:0010309]; iron ion binding [GO:0005506]; nickel cation binding [GO:0016151]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]		L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]				acireductone dioxygenase (Ni2+-requiring) activity [GO:0010308]; acireductone dioxygenase [iron(II)-requiring] activity [GO:0010309]; iron ion binding [GO:0005506]; nickel cation binding [GO:0016151]
d3loja1_d4apzw___1			Actinobacteria	Firmicutes	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3lp0a2_d3nh1d___1				Proteobacteria	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]; 3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d3lp0a2_d5j1ea2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3lp2a2_d2zd1a2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3lp3b__d1ikva1__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3lp4b__d3nipd___1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]
d3lp8a1_d2yzmb1__1			Proteobacteria	Deinococcus-Thermus	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d3lpfa2_d3vdad4__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	lactose catabolic process [GO:0005990]	cytosol [GO:0005829]	beta-galactosidase complex [GO:0009341]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3lpfb2_d4duva4__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	lactose catabolic process [GO:0005990]	cytosol [GO:0005829]	beta-galactosidase complex [GO:0009341]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3lpga2_d2je8a2__1			Proteobacteria	Bacteroidetes	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	cytosol [GO:0005829]		beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]	beta-mannosidase activity [GO:0004567]
d3lpla3_d2r8oa3__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]; cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]	glycolytic process [GO:0006096]	cellular response to antibiotic [GO:0071236]; cellular response to chloramphenicol [GO:0072747]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to menadione [GO:0036245]; cellular response to paraquat [GO:0072756]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; positive regulation of transcription, DNA-templated [GO:0045893]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	manganese ion binding [GO:0030145]; thiamine pyrophosphate binding [GO:0030976]; transketolase activity [GO:0004802]
d3lpna2_d2c4kf1__1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]; enzyme inhibitor activity [GO:0004857]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; ribose phosphate diphosphokinase complex [GO:0002189]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]	enzyme inhibitor activity [GO:0004857]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]
d3lpnb1_d3dmpd1__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]	GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; uracil phosphoribosyltransferase activity [GO:0004845]
d3lppb2_d1pz3a2__1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]	alpha-L-arabinofuranosidase activity [GO:0046556]
d3lppb3_d2guya1__1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate catabolic process [GO:0016052]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]	carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d3lppc2_d5effa___1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	xylan catabolic process [GO:0045493]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]
d3lppd1_d2fyva2__1	Metazoa	Metazoa	Chordata	Arthropoda	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d3lppd3_d1xskc3__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d3lppd3_d2pwgb2__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3lpra__d4fu8a___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]		blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular region [GO:0005576]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d3lpwa1_d2dmka1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; phosphoprotein binding [GO:0051219]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]; innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein localization to microtubule [GO:0035372]; protein ubiquitination [GO:0016567]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein localization to microtubule [GO:0035372]; protein ubiquitination [GO:0016567]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; phosphoprotein binding [GO:0051219]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d3lpwa2_d5kbnc___1	Metazoa		Chordata	Proteobacteria	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	integral component of plasma membrane [GO:0005887]; inorganic anion transmembrane transporter activity [GO:0015103]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	integral component of plasma membrane [GO:0005887]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	inorganic anion transmembrane transporter activity [GO:0015103]
d3lpwb2_d1ebab1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]
d3lpya1_d5t9pd___1	Metazoa	Fungi	Chordata	Ascomycota	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; U2-type catalytic step 2 spliceosome [GO:0071007]; cyclosporin A binding [GO:0016018]; mRNA binding [GO:0003729]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]; mRNA splicing, via spliceosome [GO:0000398]; neutrophil degranulation [GO:0043312]; positive regulation of viral genome replication [GO:0045070]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleus [GO:0005634]; preribosome, large subunit precursor [GO:0030687]; rRNA binding [GO:0019843]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit biogenesis [GO:0042273]	mRNA splicing, via spliceosome [GO:0000398]; neutrophil degranulation [GO:0043312]; positive regulation of viral genome replication [GO:0045070]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit biogenesis [GO:0042273]	catalytic step 2 spliceosome [GO:0071013]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; U2-type catalytic step 2 spliceosome [GO:0071007]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleus [GO:0005634]; preribosome, large subunit precursor [GO:0030687]	cyclosporin A binding [GO:0016018]; mRNA binding [GO:0003729]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; unfolded protein binding [GO:0051082]	rRNA binding [GO:0019843]
d3lq4a3_d1x7xb2__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; glycolytic process [GO:0006096]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]	glycolytic process [GO:0006096]	branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]		mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	metal ion binding [GO:0046872]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]
d3lq5b1_d4bcjb2__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3lq5b2_d4yoza1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; transcription factor complex [GO:0005667]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription factor binding [GO:0008134]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of cellular senescence [GO:2000773]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell division [GO:0051302]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; viral process [GO:0016032]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of cellular senescence [GO:2000773]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell division [GO:0051302]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; viral process [GO:0016032]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; transcription factor complex [GO:0005667]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	promoter-specific chromatin binding [GO:1990841]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription factor binding [GO:0008134]
d3lqca__d3t08b1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	beta-galactosidase complex [GO:0009341]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3lqdb__d3dbja___1	Metazoa		Chordata	Cyanobacteria	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3lqfd__d3btod2__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d3lqvb__d2fc8a1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U12-type spliceosomal complex [GO:0005689]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; blastocyst formation [GO:0001825]; mRNA splicing, via spliceosome [GO:0000398]	cell cortex [GO:0005938]; cytoplasmic ribonucleoprotein granule [GO:0036464]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; DNA topoisomerase binding [GO:0044547]; identical protein binding [GO:0042802]; mRNA 5'-UTR binding [GO:0048027]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]; angiogenesis [GO:0001525]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to leukemia inhibitory factor [GO:1990830]; negative regulation of translation [GO:0017148]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]	blastocyst formation [GO:0001825]; mRNA splicing, via spliceosome [GO:0000398]	angiogenesis [GO:0001525]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to leukemia inhibitory factor [GO:1990830]; negative regulation of translation [GO:0017148]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; U12-type spliceosomal complex [GO:0005689]	cell cortex [GO:0005938]; cytoplasmic ribonucleoprotein granule [GO:0036464]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	DNA topoisomerase binding [GO:0044547]; identical protein binding [GO:0042802]; mRNA 5'-UTR binding [GO:0048027]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]
d3lqwa__d4a6ab___1				Actinobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d3lr9a__d2olpb___1	Metazoa	Metazoa	Chordata	Mollusca	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3lrga1_d4lqfl1__1						integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]				integral component of membrane [GO:0016021]		metal ion binding [GO:0046872]
d3lrga1_d4u1gc2__1				Apicomplexa								
d3lrgb1_d3sy0b1__1												
d3lrsb1_d1qsfb___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3lrsd1_d1i8lb1__1		Metazoa		Chordata		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]		
d3lrsd1_d5gjtl1__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d3lrsd2_d4lsql1__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d3lrsl2_d4gt7a1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ls2c__d4y2va2__1		Metazoa	Proteobacteria	Chordata	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]; formaldehyde catabolic process [GO:0046294]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	formaldehyde catabolic process [GO:0046294]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3ls2c__d5tnsb___1			Proteobacteria	Proteobacteria	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]; formaldehyde catabolic process [GO:0046294]	hydrolase activity [GO:0016787]	formaldehyde catabolic process [GO:0046294]				carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]	hydrolase activity [GO:0016787]
d3ls4l1_d2a77l1__1												
d3ls4l2_d4q6yb2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ls4l2_d5acla___1		Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d3ls5l1_d1mcra1__1												
d3ls6b__d4p6ca___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3,4-dihydroxy-2-butanone-4-phosphate synthase activity [GO:0008686]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; 3,4-dihydroxy-2-butanone-4-phosphate synthase activity [GO:0008686]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]	cytosol [GO:0005829]	3,4-dihydroxy-2-butanone-4-phosphate synthase activity [GO:0008686]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]	3,4-dihydroxy-2-butanone-4-phosphate synthase activity [GO:0008686]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]
d3ls7a__d1zxca___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]; B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]		B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; cellular response to high density lipoprotein particle stimulus [GO:0071403]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; proteolysis [GO:0006508]; receptor transactivation [GO:0035624]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; interleukin-6 receptor binding [GO:0005138]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; Notch binding [GO:0005112]; PDZ domain binding [GO:0030165]; peptidase activity [GO:0008233]; SH3 domain binding [GO:0017124]
d3lsda__d4ovwa___1	Metazoa	Fungi	Chordata	Ascomycota	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	cellulose catabolic process [GO:0030245]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	cellulase activity [GO:0008810]
d3lsea__d2cy6d___1	Metazoa	Viridiplantae	Chordata	Streptophyta	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3lsxa__d4kptb___1	Metazoa		Chordata	Firmicutes	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	nitrogen compound transport [GO:0071705]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ligand-gated ion channel activity [GO:0015276]
d3lted1_d5chya___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		cytosol [GO:0005829]	DNA binding [GO:0003677]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d3ltee1_d3cz5d___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d3lteh1_d1oxkj___1		Fungi	Proteobacteria	Ascomycota	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]; osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]	phosphorelay signal transduction system [GO:0000160]	osmosensory signaling via phosphorelay pathway [GO:0007234]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	DNA binding [GO:0003677]	histidine phosphotransfer kinase activity [GO:0009927]; protein histidine kinase binding [GO:0043424]; transferase activity, transferring phosphorus-containing groups [GO:0016772]
d3ltel__d1zh4b___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]	regulation of transcription, DNA-templated [GO:0006355]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3lteq__d1w25a1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; phosphorelay signal transduction system [GO:0000160]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]	diguanylate cyclase activity [GO:0052621]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]
d3ltex__d2flwa___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	phosphorelay signal transduction system [GO:0000160]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]	metal ion binding [GO:0046872]
d3ltla__d4a4pb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; small nuclear ribonucleoprotein complex [GO:0030532]; trans-Golgi network [GO:0005802]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; guanyl-nucleotide exchange factor activity [GO:0005085]; myosin binding [GO:0017022]; protein kinase A regulatory subunit binding [GO:0034237]; endomembrane system organization [GO:0010256]; exocytosis [GO:0006887]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; neuron projection development [GO:0031175]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein glycosylation in Golgi [GO:0090284]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of wound healing [GO:0090303]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; lipid binding [GO:0008289]; establishment of epithelial cell polarity [GO:0090162]; regulation of ARF protein signal transduction [GO:0032012]; regulation of cell adhesion [GO:0030155]; vesicle-mediated transport [GO:0016192]	endomembrane system organization [GO:0010256]; exocytosis [GO:0006887]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; neuron projection development [GO:0031175]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein glycosylation in Golgi [GO:0090284]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of wound healing [GO:0090303]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114]	establishment of epithelial cell polarity [GO:0090162]; regulation of ARF protein signal transduction [GO:0032012]; regulation of cell adhesion [GO:0030155]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; small nuclear ribonucleoprotein complex [GO:0030532]; trans-Golgi network [GO:0005802]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; guanyl-nucleotide exchange factor activity [GO:0005085]; myosin binding [GO:0017022]; protein kinase A regulatory subunit binding [GO:0034237]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; lipid binding [GO:0008289]
d3ltlb__d1r8qf___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; small nuclear ribonucleoprotein complex [GO:0030532]; trans-Golgi network [GO:0005802]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; guanyl-nucleotide exchange factor activity [GO:0005085]; myosin binding [GO:0017022]; protein kinase A regulatory subunit binding [GO:0034237]; endomembrane system organization [GO:0010256]; exocytosis [GO:0006887]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; neuron projection development [GO:0031175]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein glycosylation in Golgi [GO:0090284]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of wound healing [GO:0090303]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; inositol 1,4,5 trisphosphate binding [GO:0070679]; lipid binding [GO:0008289]; actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; regulation of ARF protein signal transduction [GO:0032012]	endomembrane system organization [GO:0010256]; exocytosis [GO:0006887]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; neuron projection development [GO:0031175]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein glycosylation in Golgi [GO:0090284]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of wound healing [GO:0090303]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114]	actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; regulation of ARF protein signal transduction [GO:0032012]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; small nuclear ribonucleoprotein complex [GO:0030532]; trans-Golgi network [GO:0005802]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; guanyl-nucleotide exchange factor activity [GO:0005085]; myosin binding [GO:0017022]; protein kinase A regulatory subunit binding [GO:0034237]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; inositol 1,4,5 trisphosphate binding [GO:0070679]; lipid binding [GO:0008289]
d3ltpa__d3ctld___1			Euryarchaeota	Proteobacteria	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		cytosol [GO:0005829]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3ltve__d1z9nb___1	Metazoa		Chordata	Proteobacteria	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]		axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	periplasmic space [GO:0042597]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ltya__d5lnvc___1		Viridiplantae	Euryarchaeota	Streptophyta	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]; amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]		cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3lu6a3_d5oswa1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d3lu7b1_d4e99a3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3lu7b1_d5hoza2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3lu7b3_d4luha3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	enterobactin binding [GO:1903981]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d3lu8a1_d4f5sb3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3lu8b3_d3cx9a2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3luda__d4krea2__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mRNA cap binding complex [GO:0005845]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]; core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; endoribonuclease activity [GO:0004521]; endoribonuclease activity, cleaving miRNA-paired mRNA [GO:0090624]; endoribonuclease activity, cleaving siRNA-paired mRNA [GO:0070551]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA cap binding [GO:0098808]; protein C-terminus binding [GO:0008022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; translation initiation factor activity [GO:0003743]; gene silencing by RNA [GO:0031047]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; mRNA cleavage involved in gene silencing by siRNA [GO:0090625]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of gene expression [GO:0010629]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene silencing by miRNA [GO:0060964]; RNA secondary structure unwinding [GO:0010501]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; translation [GO:0006412]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]; core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded RNA binding [GO:0003727]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; negative regulation of angiogenesis [GO:0016525]; negative regulation of gene expression [GO:0010629]; nuclear-transcribed mRNA catabolic process [GO:0000956]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA secondary structure unwinding [GO:0010501]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	gene silencing by RNA [GO:0031047]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; mRNA cleavage involved in gene silencing by siRNA [GO:0090625]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of gene expression [GO:0010629]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene silencing by miRNA [GO:0060964]; RNA secondary structure unwinding [GO:0010501]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; translation [GO:0006412]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; negative regulation of angiogenesis [GO:0016525]; negative regulation of gene expression [GO:0010629]; nuclear-transcribed mRNA catabolic process [GO:0000956]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA secondary structure unwinding [GO:0010501]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mRNA cap binding complex [GO:0005845]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]	core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; endoribonuclease activity [GO:0004521]; endoribonuclease activity, cleaving miRNA-paired mRNA [GO:0090624]; endoribonuclease activity, cleaving siRNA-paired mRNA [GO:0070551]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA cap binding [GO:0098808]; protein C-terminus binding [GO:0008022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; translation initiation factor activity [GO:0003743]	core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded RNA binding [GO:0003727]
d3luga__d4g0za1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mRNA cap binding complex [GO:0005845]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]; core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; endoribonuclease activity [GO:0004521]; endoribonuclease activity, cleaving miRNA-paired mRNA [GO:0090624]; endoribonuclease activity, cleaving siRNA-paired mRNA [GO:0070551]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA cap binding [GO:0098808]; protein C-terminus binding [GO:0008022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; translation initiation factor activity [GO:0003743]; gene silencing by RNA [GO:0031047]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; mRNA cleavage involved in gene silencing by siRNA [GO:0090625]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of gene expression [GO:0010629]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene silencing by miRNA [GO:0060964]; RNA secondary structure unwinding [GO:0010501]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; translation [GO:0006412]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; adaxial/abaxial pattern specification [GO:0009955]; adventitious root development [GO:0048830]; auxin metabolic process [GO:0009850]; cell differentiation [GO:0030154]; defense response to virus [GO:0051607]; gene silencing by miRNA [GO:0035195]; innate immune response [GO:0045087]; leaf morphogenesis [GO:0009965]; leaf proximal/distal pattern formation [GO:0010589]; leaf vascular tissue pattern formation [GO:0010305]; posttranscriptional gene silencing [GO:0016441]; regulation of translation [GO:0006417]; response to auxin [GO:0009733]; response to far red light [GO:0010218]; viral gene silencing in virus induced gene silencing [GO:0060145]; viral process [GO:0016032]; virus induced gene silencing [GO:0009616]	gene silencing by RNA [GO:0031047]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; mRNA cleavage involved in gene silencing by siRNA [GO:0090625]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of gene expression [GO:0010629]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene silencing by miRNA [GO:0060964]; RNA secondary structure unwinding [GO:0010501]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; translation [GO:0006412]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	adaxial/abaxial pattern specification [GO:0009955]; adventitious root development [GO:0048830]; auxin metabolic process [GO:0009850]; cell differentiation [GO:0030154]; defense response to virus [GO:0051607]; gene silencing by miRNA [GO:0035195]; innate immune response [GO:0045087]; leaf morphogenesis [GO:0009965]; leaf proximal/distal pattern formation [GO:0010589]; leaf vascular tissue pattern formation [GO:0010305]; posttranscriptional gene silencing [GO:0016441]; regulation of translation [GO:0006417]; response to auxin [GO:0009733]; response to far red light [GO:0010218]; viral gene silencing in virus induced gene silencing [GO:0060145]; viral process [GO:0016032]; virus induced gene silencing [GO:0009616]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mRNA cap binding complex [GO:0005845]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; endoribonuclease activity [GO:0004521]; endoribonuclease activity, cleaving miRNA-paired mRNA [GO:0090624]; endoribonuclease activity, cleaving siRNA-paired mRNA [GO:0070551]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA cap binding [GO:0098808]; protein C-terminus binding [GO:0008022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; translation initiation factor activity [GO:0003743]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]
d3lugc__d2bgga2__1	Metazoa		Chordata	Euryarchaeota	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mRNA cap binding complex [GO:0005845]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]; core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; endoribonuclease activity [GO:0004521]; endoribonuclease activity, cleaving miRNA-paired mRNA [GO:0090624]; endoribonuclease activity, cleaving siRNA-paired mRNA [GO:0070551]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA cap binding [GO:0098808]; protein C-terminus binding [GO:0008022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; translation initiation factor activity [GO:0003743]; gene silencing by RNA [GO:0031047]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; mRNA cleavage involved in gene silencing by siRNA [GO:0090625]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of gene expression [GO:0010629]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene silencing by miRNA [GO:0060964]; RNA secondary structure unwinding [GO:0010501]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; translation [GO:0006412]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	gene silencing by RNA [GO:0031047]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; mRNA cleavage involved in gene silencing by siRNA [GO:0090625]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of gene expression [GO:0010629]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene silencing by miRNA [GO:0060964]; RNA secondary structure unwinding [GO:0010501]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; translation [GO:0006412]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mRNA cap binding complex [GO:0005845]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]		core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; endoribonuclease activity [GO:0004521]; endoribonuclease activity, cleaving miRNA-paired mRNA [GO:0090624]; endoribonuclease activity, cleaving siRNA-paired mRNA [GO:0070551]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA cap binding [GO:0098808]; protein C-terminus binding [GO:0008022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; translation initiation factor activity [GO:0003743]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3luha__d4g0pa1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mRNA cap binding complex [GO:0005845]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]; core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; endoribonuclease activity [GO:0004521]; endoribonuclease activity, cleaving miRNA-paired mRNA [GO:0090624]; endoribonuclease activity, cleaving siRNA-paired mRNA [GO:0070551]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA cap binding [GO:0098808]; protein C-terminus binding [GO:0008022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; translation initiation factor activity [GO:0003743]; gene silencing by RNA [GO:0031047]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; mRNA cleavage involved in gene silencing by siRNA [GO:0090625]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of gene expression [GO:0010629]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene silencing by miRNA [GO:0060964]; RNA secondary structure unwinding [GO:0010501]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; translation [GO:0006412]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; adaxial/abaxial pattern specification [GO:0009955]; adventitious root development [GO:0048830]; auxin metabolic process [GO:0009850]; cell differentiation [GO:0030154]; defense response to virus [GO:0051607]; gene silencing by miRNA [GO:0035195]; innate immune response [GO:0045087]; leaf morphogenesis [GO:0009965]; leaf proximal/distal pattern formation [GO:0010589]; leaf vascular tissue pattern formation [GO:0010305]; posttranscriptional gene silencing [GO:0016441]; regulation of translation [GO:0006417]; response to auxin [GO:0009733]; response to far red light [GO:0010218]; viral gene silencing in virus induced gene silencing [GO:0060145]; viral process [GO:0016032]; virus induced gene silencing [GO:0009616]	gene silencing by RNA [GO:0031047]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; mRNA cleavage involved in gene silencing by siRNA [GO:0090625]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of gene expression [GO:0010629]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene silencing by miRNA [GO:0060964]; RNA secondary structure unwinding [GO:0010501]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; translation [GO:0006412]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	adaxial/abaxial pattern specification [GO:0009955]; adventitious root development [GO:0048830]; auxin metabolic process [GO:0009850]; cell differentiation [GO:0030154]; defense response to virus [GO:0051607]; gene silencing by miRNA [GO:0035195]; innate immune response [GO:0045087]; leaf morphogenesis [GO:0009965]; leaf proximal/distal pattern formation [GO:0010589]; leaf vascular tissue pattern formation [GO:0010305]; posttranscriptional gene silencing [GO:0016441]; regulation of translation [GO:0006417]; response to auxin [GO:0009733]; response to far red light [GO:0010218]; viral gene silencing in virus induced gene silencing [GO:0060145]; viral process [GO:0016032]; virus induced gene silencing [GO:0009616]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mRNA cap binding complex [GO:0005845]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; endoribonuclease activity [GO:0004521]; endoribonuclease activity, cleaving miRNA-paired mRNA [GO:0090624]; endoribonuclease activity, cleaving siRNA-paired mRNA [GO:0070551]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA cap binding [GO:0098808]; protein C-terminus binding [GO:0008022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; translation initiation factor activity [GO:0003743]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]
d3luta__d1s1ra___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]; 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; prostaglandin-F synthase activity [GO:0047017]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin-F synthase activity [GO:0047017]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]
d3lv3b1_d1b4jl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3lv3b1_d1q9vb4__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3lv6b__d1rpxc___1		Viridiplantae	Euryarchaeota	Streptophyta	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	chloroplast thylakoid membrane [GO:0009535]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pentose-phosphate shunt [GO:0006098]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast thylakoid membrane [GO:0009535]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3lvba1_d3vo2b1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	electron transfer activity [GO:0009055]; NADPH binding [GO:0070402]; NADPH dehydrogenase activity [GO:0003959]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]			chloroplast [GO:0009507]	electron transfer activity [GO:0009055]; NADPH binding [GO:0070402]; NADPH dehydrogenase activity [GO:0003959]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d3lvba2_d2bsaa2__1	Viridiplantae		Streptophyta	Cyanobacteria	electron transfer activity [GO:0009055]; NADPH binding [GO:0070402]; NADPH dehydrogenase activity [GO:0003959]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]	electron transfer activity [GO:0009055]; NADPH binding [GO:0070402]; NADPH dehydrogenase activity [GO:0003959]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d3lvea__d2oldb1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]	
d3lvla__d2qq4c___1			Proteobacteria	Deinococcus-Thermus	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]; iron-sulfur cluster assembly [GO:0016226]	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]; iron-sulfur cluster assembly [GO:0016226]	iron-sulfur cluster assembly [GO:0016226]	iron-sulfur cluster assembly [GO:0016226]			iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]	iron ion binding [GO:0005506]; iron-sulfur cluster binding [GO:0051536]
d3lwwa__d1o6pa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear pore [GO:0005643]; nuclear import signal receptor activity [GO:0061608]; RNA cap binding [GO:0000339]; import into nucleus [GO:0051170]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]; spliceosomal snRNP assembly [GO:0000387]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; enzyme binding [GO:0019899]; Hsp90 protein binding [GO:0051879]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein domain specific binding [GO:0019904]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; apoptotic DNA fragmentation [GO:0006309]; astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; intracellular transport of virus [GO:0075733]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; modulation by virus of host cellular process [GO:0019054]; neutrophil degranulation [GO:0043312]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal protein import into nucleus [GO:0006610]	import into nucleus [GO:0051170]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]; spliceosomal snRNP assembly [GO:0000387]	apoptotic DNA fragmentation [GO:0006309]; astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; intracellular transport of virus [GO:0075733]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; modulation by virus of host cellular process [GO:0019054]; neutrophil degranulation [GO:0043312]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; Ran protein signal transduction [GO:0031291]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal protein import into nucleus [GO:0006610]	cytosol [GO:0005829]; nuclear pore [GO:0005643]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; endoplasmic reticulum tubular network [GO:0071782]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	nuclear import signal receptor activity [GO:0061608]; RNA cap binding [GO:0000339]	enzyme binding [GO:0019899]; Hsp90 protein binding [GO:0051879]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein domain specific binding [GO:0019904]; Ran GTPase binding [GO:0008536]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3lwwa__d3q7jb4__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; nuclear pore [GO:0005643]; nuclear import signal receptor activity [GO:0061608]; RNA cap binding [GO:0000339]; import into nucleus [GO:0051170]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]; spliceosomal snRNP assembly [GO:0000387]	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	import into nucleus [GO:0051170]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]; spliceosomal snRNP assembly [GO:0000387]		cytosol [GO:0005829]; nuclear pore [GO:0005643]	cytoplasm [GO:0005737]	nuclear import signal receptor activity [GO:0061608]; RNA cap binding [GO:0000339]	aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]
d3lx1a2_d1vyji2__1		Metazoa	Euryarchaeota	Chordata	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	PCNA complex [GO:0043626]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d3lx2a2_d1w60b2__1		Metazoa	Euryarchaeota	Chordata	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	PCNA complex [GO:0043626]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d3lx2b1_d3f1wa1__1		Fungi	Euryarchaeota	Ascomycota	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	PCNA complex [GO:0043626]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]
d3lx2b1_d5a6da2__1			Euryarchaeota	Euryarchaeota	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	PCNA complex [GO:0043626]		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d3lx2b2_d1vymb1__1		Metazoa	Euryarchaeota	Chordata	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	PCNA complex [GO:0043626]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]
d3lx2c1_d3bepa3__1			Euryarchaeota	Proteobacteria	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	PCNA complex [GO:0043626]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3lx2c2_d4mjra3__1			Euryarchaeota	Proteobacteria	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	PCNA complex [GO:0043626]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3lx3a__d1gtpm___1			Apicomplexa	Proteobacteria	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d3lx9a1_d1mw3a2__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	amylosucrase activity [GO:0047669]
d3lx9a1_d3mv143__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	beta-galactosidase complex [GO:0009341]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3lx9a2_d2wspb2__1	Metazoa		Chordata	Thermotogae	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	lysosome [GO:0005764]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-L-fucosidase activity [GO:0004560]
d3lx9b1_d2xvnb___1	Metazoa	Fungi	Chordata	Ascomycota	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	anchored component of membrane [GO:0031225]; cell wall [GO:0005618]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	anchored component of membrane [GO:0031225]; cell wall [GO:0005618]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d3lx9b2_d4lq1c3__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	cytosol [GO:0005829]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3lxaa1_d3hg5a1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d3lxaa2_d1jfha1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate catabolic process [GO:0016052]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular space [GO:0005615]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3lxaa2_d2f2ha3__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d3lxbb1_d1qnra___1	Metazoa	Fungi	Chordata	Ascomycota	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	cellulose binding [GO:0030248]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]
d3lxbb2_d3olea2__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3lxcb1_d3h53b1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d3lxeb__d3n4ba___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3lxfa__d2w3re1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3lxfb__d4zhob1__1		Viridiplantae	Proteobacteria	Streptophyta	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	chloroplast [GO:0009507]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; photosynthetic acclimation [GO:0009643]; photosynthetic electron transport chain [GO:0009767]		photosynthetic acclimation [GO:0009643]; photosynthetic electron transport chain [GO:0009767]		chloroplast [GO:0009507]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3lxfc__d4ysxf1__1		Metazoa	Proteobacteria	Nematoda (roundworms)	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle [GO:0006099]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d3lxfd__d3am9b1__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d3lxfe__d2cjna___1			Proteobacteria	Cyanobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3lxga__d1mkdg___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d3lxhb__d1phga___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3lxib__d2uwhc___1			Proteobacteria	Firmicutes	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]			integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d3lxja1_d5pg3a1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; lysine-acetylated histone binding [GO:0070577]; negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription by RNA polymerase II [GO:0045944]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription by RNA polymerase II [GO:0045944]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleus [GO:0005634]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; lysine-acetylated histone binding [GO:0070577]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d3lxjb1_d5nrwa___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; lysine-acetylated histone binding [GO:0070577]; negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription by RNA polymerase II [GO:0045944]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription by RNA polymerase II [GO:0045944]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; lysine-acetylated histone binding [GO:0070577]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3lxva__d5umha___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	catechol 1,2-dioxygenase activity [GO:0018576]; ferric iron binding [GO:0008199]; catechol-containing compound catabolic process [GO:0019614]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	catechol-containing compound catabolic process [GO:0019614]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	catechol 1,2-dioxygenase activity [GO:0018576]; ferric iron binding [GO:0008199]
d3ly2a1_d2gz4d___1	Metazoa		Chordata	Proteobacteria	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]		cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]		centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]		3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	
d3ly2c__d1y2da___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d3ly2f__d1xoza___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	cytosol [GO:0005829]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]
d3ly2h__d3tgea___1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	cytosol [GO:0005829]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]
d3ly6a4_d4ktya4__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d3ly6c2_d3irtb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; adult walking behavior [GO:0007628]; axon target recognition [GO:0007412]; axonal transport of mitochondrion [GO:0019896]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	adult walking behavior [GO:0007628]; axonal transport of mitochondrion [GO:0019896]; axon target recognition [GO:0007412]; cell population proliferation [GO:0008283]; eating behavior [GO:0042755]; muscle fiber development [GO:0048747]; negative regulation of MAP kinase activity [GO:0043407]; neuromuscular process [GO:0050905]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; regulation of macroautophagy [GO:0016241]; response to ischemia [GO:0002931]; sensory perception of pain [GO:0019233]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	alpha-2A adrenergic receptor binding [GO:0031694]; cysteine-type endopeptidase activity [GO:0004197]; ligase activity [GO:0016874]; omega peptidase activity [GO:0008242]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]
d3ly6c3_d4ktyb3__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]; metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	apoptotic cell clearance [GO:0043277]; blood vessel remodeling [GO:0001974]; branching involved in salivary gland morphogenesis [GO:0060445]; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peptide cross-linking [GO:0018149]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein homooligomerization [GO:0051260]; salivary gland cavitation [GO:0060662]	blood coagulation [GO:0007596]; blood coagulation, fibrin clot formation [GO:0072378]; cytokine-mediated signaling pathway [GO:0019221]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; intrinsic component of plasma membrane [GO:0031226]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; platelet alpha granule lumen [GO:0031093]	GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]	metal ion binding [GO:0046872]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]
d3lyjc__d4bsga___1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d3lyje__d4wstc1__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d3lyjg__d4bh1c___1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d3lyma__d3dn6a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3lyta__d5jwsa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3lytb__d1b5za___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3lytb__d1g0pa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3lz1c__d1f66f___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3lz1e__d2jssa1__1	Metazoa	Fungi	Chordata	Ascomycota	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleosome [GO:0000786]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromatin silencing at silent mating-type cassette [GO:0030466]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; regulation of transcription by RNA polymerase II [GO:0006357]		chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromatin silencing at silent mating-type cassette [GO:0030466]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d3lz2a__d1l03a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3lz6b__d4uuna1__1	Metazoa		Chordata		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; lung development [GO:0030324]; steroid metabolic process [GO:0008202]	L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	lung development [GO:0030324]; steroid metabolic process [GO:0008202]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]	L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]; nucleotide binding [GO:0000166]
d3lzea__d1is7i___1		Metazoa	Apicomplexa	Chordata	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]		negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]
d3lzfl2_d3vxta1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d3lzgc__d4qy1u___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3lzgc__d5bnya___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3lzgg__d5vtve1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d3lzgk1_d4k65g1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3lzja1_d2hbma2__1		Fungi		Ascomycota	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleus [GO:0005634]; 3'-5'-exoribonuclease activity [GO:0000175]; nucleotide binding [GO:0000166]; single-stranded RNA binding [GO:0003727]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; histone mRNA catabolic process [GO:0071044]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent antisense transcript catabolic process [GO:0071040]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent snoRNA catabolic process [GO:0071036]; nuclear polyadenylation-dependent snRNA catabolic process [GO:0071037]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; histone mRNA catabolic process [GO:0071044]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent antisense transcript catabolic process [GO:0071040]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent snoRNA catabolic process [GO:0071036]; nuclear polyadenylation-dependent snRNA catabolic process [GO:0071037]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]		nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleus [GO:0005634]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3'-5'-exoribonuclease activity [GO:0000175]; nucleotide binding [GO:0000166]; single-stranded RNA binding [GO:0003727]
d3lzlb__d3pjlb___1			Proteobacteria	Spirochaetes	metal ion binding [GO:0046872]	plasma membrane [GO:0005886]				plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	
d3lzob1_d3nrqb___1			Proteobacteria		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]	
d3lzub__d1w5xa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3lzva__d4y51a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3lzzb__d1vj2b___1	Metazoa		Chordata	Thermotogae		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d3m02a2_d3wcfc___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d3m08a1_d4q0ec1__1			Firmicutes		dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	
d3m09a1_d1rx8a___1			Firmicutes	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d3m0ea__d3hu2e3__1		Metazoa	Aquificae	Chordata	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d3m0ed__d3tmkh___1		Fungi	Aquificae	Ascomycota	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; nucleoside diphosphate phosphorylation [GO:0006165]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; nucleoside diphosphate phosphorylation [GO:0006165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]
d3m0na__d2yzbh1__1			Apicomplexa	Actinobacteria	metal ion binding [GO:0046872]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]			metal ion binding [GO:0046872]	urate oxidase activity [GO:0004846]
d3m0na__d3lx3a___1			Apicomplexa	Apicomplexa	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3m0wa__d1f8ha___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]; clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	clathrin coat assembly [GO:0048268]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of receptor recycling [GO:0001921]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of cell population proliferation [GO:0042127]; vesicle organization [GO:0016050]; viral entry into host cell [GO:0046718]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	aggresome [GO:0016235]; AP-2 adaptor complex [GO:0030122]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; ciliary membrane [GO:0060170]; clathrin-coated pit [GO:0005905]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; polyubiquitin modification-dependent protein binding [GO:0031593]; SH3 domain binding [GO:0017124]
d3m0wh__d2y5id___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	calcium ion binding [GO:0005509]	epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]		collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]		actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]	calcium ion binding [GO:0005509]
d3m10b1_d1n16a3__1	Metazoa		Arthropoda		cytoplasm [GO:0005737]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]		cytoplasm [GO:0005737]		arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	
d3m15b__d1e85a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3m15b__d2bc5b___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3m17h__d5hysg2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3m1bb__d5m2mh1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d3m1bd__d2r2eb1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3m1bd__d4b7ia1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3m1bf__d1v7nl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]
d3m1bh__d2pw2b1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3m1ib__d1w1hb1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; GTPase activator activity [GO:0005096]; Ran GTPase binding [GO:0008536]; G1/S transition of mitotic cell cycle [GO:0000082]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	G1/S transition of mitotic cell cycle [GO:0000082]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; ubiquitin-dependent protein catabolic process [GO:0006511]	actin cytoskeleton organization [GO:0030036]; activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; Fc-epsilon receptor signaling pathway [GO:0038095]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; type B pancreatic cell development [GO:0003323]	cytoplasm [GO:0005737]; nuclear pore [GO:0005643]; nucleus [GO:0005634]	cell [GO:0005623]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	GTPase activator activity [GO:0005096]; Ran GTPase binding [GO:0008536]	3-phosphoinositide-dependent protein kinase activity [GO:0004676]; ATP binding [GO:0005524]; insulin receptor binding [GO:0005158]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]
d3m1ja__d4xixa___1	Metazoa	Viridiplantae	Chordata	Chlorophyta	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3m1nb__d1xp2b1__1	Metazoa		Chordata		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; laminin-1 binding [GO:0043237]; morphogen activity [GO:0016015]; patched binding [GO:0005113]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]; androgen metabolic process [GO:0008209]; animal organ formation [GO:0048645]; apoptotic signaling pathway [GO:0097190]; artery development [GO:0060840]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; blood coagulation [GO:0007596]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bud outgrowth involved in lung branching [GO:0060447]; camera-type eye development [GO:0043010]; canonical Wnt signaling pathway [GO:0060070]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell development [GO:0048468]; cell fate specification [GO:0001708]; cell-cell signaling [GO:0007267]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; cerebellar granule cell precursor proliferation [GO:0021930]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic skeletal system development [GO:0048706]; endocytosis [GO:0006897]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial-mesenchymal signaling involved in prostate gland development [GO:0060738]; establishment of cell polarity [GO:0030010]; forebrain development [GO:0030900]; formation of anatomical boundary [GO:0048859]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; inner ear development [GO:0048839]; intein-mediated protein splicing [GO:0016539]; intermediate filament organization [GO:0045109]; left lung development [GO:0060459]; limb bud formation [GO:0060174]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; lymphoid progenitor cell differentiation [GO:0002320]; male genitalia development [GO:0030539]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal smoothened signaling pathway involved in prostate gland development [GO:0060783]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephros development [GO:0001656]; midbrain development [GO:0030901]; myoblast differentiation [GO:0045445]; myotube differentiation [GO:0014902]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of kidney smooth muscle cell differentiation [GO:2000357]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of ureter smooth muscle cell differentiation [GO:2000062]; negative thymic T cell selection [GO:0045060]; neural crest cell migration [GO:0001755]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; osteoblast development [GO:0002076]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; polarity specification of anterior/posterior axis [GO:0009949]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of kidney smooth muscle cell differentiation [GO:2000358]; positive regulation of mesenchymal cell proliferation involved in ureter development [GO:2000729]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sclerotome development [GO:0061189]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ureter smooth muscle cell differentiation [GO:2000063]; positive regulation of Wnt signaling pathway [GO:0030177]; positive thymic T cell selection [GO:0045059]; primary prostatic bud elongation [GO:0060516]; prostate epithelial cord elongation [GO:0060523]; prostate gland development [GO:0030850]; protein localization to nucleus [GO:0034504]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782]; regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry [GO:1900175]; regulation of odontogenesis [GO:0042481]; regulation of prostatic bud formation [GO:0060685]; regulation of protein localization to nucleus [GO:1900180]; regulation of proteolysis [GO:0030162]; renal system development [GO:0072001]; right lung development [GO:0060458]; roof of mouth development [GO:0060021]; salivary gland cavitation [GO:0060662]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; somite development [GO:0061053]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord motor neuron differentiation [GO:0021522]; stem cell development [GO:0048864]; striated muscle tissue development [GO:0014706]; T cell differentiation in thymus [GO:0033077]; telencephalon regionalization [GO:0021978]; thalamus development [GO:0021794]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea morphogenesis [GO:0060439]; tracheoesophageal septum formation [GO:1905327]; vasculogenesis [GO:0001570]; ventral midline development [GO:0007418]		androgen metabolic process [GO:0008209]; animal organ formation [GO:0048645]; apoptotic signaling pathway [GO:0097190]; artery development [GO:0060840]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; blood coagulation [GO:0007596]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bud outgrowth involved in lung branching [GO:0060447]; camera-type eye development [GO:0043010]; canonical Wnt signaling pathway [GO:0060070]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell-cell signaling [GO:0007267]; cell development [GO:0048468]; cell fate specification [GO:0001708]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; cerebellar granule cell precursor proliferation [GO:0021930]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic skeletal system development [GO:0048706]; endocytosis [GO:0006897]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial-mesenchymal signaling involved in prostate gland development [GO:0060738]; establishment of cell polarity [GO:0030010]; forebrain development [GO:0030900]; formation of anatomical boundary [GO:0048859]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; inner ear development [GO:0048839]; intein-mediated protein splicing [GO:0016539]; intermediate filament organization [GO:0045109]; left lung development [GO:0060459]; limb bud formation [GO:0060174]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung lobe morphogenesis [GO:0060463]; lymphoid progenitor cell differentiation [GO:0002320]; male genitalia development [GO:0030539]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal smoothened signaling pathway involved in prostate gland development [GO:0060783]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephros development [GO:0001656]; midbrain development [GO:0030901]; myoblast differentiation [GO:0045445]; myotube differentiation [GO:0014902]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of kidney smooth muscle cell differentiation [GO:2000357]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of ureter smooth muscle cell differentiation [GO:2000062]; negative thymic T cell selection [GO:0045060]; neural crest cell migration [GO:0001755]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; osteoblast development [GO:0002076]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; polarity specification of anterior/posterior axis [GO:0009949]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of kidney smooth muscle cell differentiation [GO:2000358]; positive regulation of mesenchymal cell proliferation involved in ureter development [GO:2000729]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sclerotome development [GO:0061189]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ureter smooth muscle cell differentiation [GO:2000063]; positive regulation of Wnt signaling pathway [GO:0030177]; positive thymic T cell selection [GO:0045059]; primary prostatic bud elongation [GO:0060516]; prostate epithelial cord elongation [GO:0060523]; prostate gland development [GO:0030850]; protein localization to nucleus [GO:0034504]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782]; regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry [GO:1900175]; regulation of odontogenesis [GO:0042481]; regulation of prostatic bud formation [GO:0060685]; regulation of protein localization to nucleus [GO:1900180]; regulation of proteolysis [GO:0030162]; renal system development [GO:0072001]; right lung development [GO:0060458]; roof of mouth development [GO:0060021]; salivary gland cavitation [GO:0060662]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; somite development [GO:0061053]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord motor neuron differentiation [GO:0021522]; stem cell development [GO:0048864]; striated muscle tissue development [GO:0014706]; T cell differentiation in thymus [GO:0033077]; telencephalon regionalization [GO:0021978]; thalamus development [GO:0021794]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea morphogenesis [GO:0060439]; tracheoesophageal septum formation [GO:1905327]; vasculogenesis [GO:0001570]; ventral midline development [GO:0007418]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; laminin-1 binding [GO:0043237]; morphogen activity [GO:0016015]; patched binding [GO:0005113]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]	
d3m1pa__d2vvoc___1				Actinobacteria	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]	identical protein binding [GO:0042802]; isomerase activity [GO:0016853]	ribose-5-phosphate isomerase activity [GO:0004751]
d3m1ve1_d3sqgb1__1			Euryarchaeota		cytoplasm [GO:0005737]; coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]; methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	cytoplasm [GO:0005737]		coenzyme-B sulfoethylthiotransferase activity [GO:0050524]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]
d3m1wa__d5tv3a___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3m23a__d5cibc___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3m25a__d1iyna___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3m27a__d5kq0a2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3m2ba__d1u2la1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to hydrogen peroxide [GO:0070301]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]; peroxidase activity [GO:0004601]
d3m2ca__d5kqhb2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3m2fa__d2euna2__1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3m2ha__d5kt9a2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3m2ia__d4bm4a___1	Fungi	Fungi	Ascomycota	Basidiomycota	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3m2ue1_d5n28b1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	cytoplasm [GO:0005737]		coenzyme-B sulfoethylthiotransferase activity [GO:0050524]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]
d3m2vb1_d3sqge1__1			Euryarchaeota		cytoplasm [GO:0005737]; coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]; methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	cytoplasm [GO:0005737]		coenzyme-B sulfoethylthiotransferase activity [GO:0050524]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]
d3m3ca1_d3ovwa___1	Fungi	Fungi	Basidiomycota	Ascomycota	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	cellulose catabolic process [GO:0030245]			deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	cellulase activity [GO:0008810]
d3m3ea1_d1hv1a___1	Fungi		Basidiomycota	Firmicutes	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	xylan catabolic process [GO:0045493]			deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	endo-1,4-beta-xylanase activity [GO:0031176]
d3m3ea1_d5ewse___1	Fungi	Metazoa	Basidiomycota	Chordata	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]				deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]
d3m3fa__d4ymab___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3m3ke__d1oibb___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	phosphate ion binding [GO:0042301]
d3m3la__d4gwob___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; cysteine biosynthetic process [GO:0019344]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cysteine biosynthetic process [GO:0019344]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cytoplasm [GO:0005737]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3m3ld__d2xwoa1__1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d3m3lg__d3u94d1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3m3qa1_d3pvoa___1	Fungi	Metazoa	Basidiomycota	Chordata	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d3m3qa1_d5jp5e___1	Fungi	Metazoa	Basidiomycota	Chordata	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	cytoplasm [GO:0005737]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; lymphatic endothelial cell migration [GO:1904977]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	lymphatic endothelial cell migration [GO:1904977]		cytoplasm [GO:0005737]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d3m3sa__d1kxfa___1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]
d3m3sb__d1elta___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3m3ta1_d2gch.1__1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3m3ua__d1qt5a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3m3va__d2qxgb___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; positive regulation of antibacterial peptide production [GO:0002803]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	epidermal lamellar body [GO:0097209]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3m3va__d3zz6a1__1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3m3za1_d1rfqa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3m3za2_d4ijnb1__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]
d3m4bb__d5jvea___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3m4ca__d2xm4a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3m4cb__d3qw1c___1			Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	
d3m4cd__d2ylia___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3m4cd__d3foog___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3m4gb__d1i8ff1__1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]		pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]		cytosol [GO:0005829]		RNA binding [GO:0003723]	
d3m4gd__d3sb2e___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	RNA binding [GO:0003723]; regulation of transcription, DNA-templated [GO:0006355]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]		RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3m4gd__d4nl3d___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]; RNA binding [GO:0003723]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]	cytosol [GO:0005829]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3m4gj__d5szdk1__1			Proteobacteria	Aquificae	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]; RNA binding [GO:0003723]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]	cytosol [GO:0005829]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3m4sb__d1qaha___1		Metazoa		Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]; deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ion binding [GO:0043167]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; transition metal ion binding [GO:0046914]; brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	organonitrogen compound catabolic process [GO:1901565]	brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]	deaminase activity [GO:0019239]	deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ion binding [GO:0043167]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; transition metal ion binding [GO:0046914]
d3m4sc__d1x25a1__1				Crenarchaeota	cytosol [GO:0005829]; mitochondrion [GO:0005739]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]		organonitrogen compound catabolic process [GO:1901565]		cytosol [GO:0005829]; mitochondrion [GO:0005739]		deaminase activity [GO:0019239]	
d3m4sd__d5hp8a___1		Viridiplantae		Streptophyta	cytosol [GO:0005829]; mitochondrion [GO:0005739]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plastid [GO:0009536]; thylakoid [GO:0009579]; vacuole [GO:0005773]; deaminase activity [GO:0019239]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; organonitrogen compound catabolic process [GO:1901565]; response to cadmium ion [GO:0046686]; response to toxic substance [GO:0009636]	organonitrogen compound catabolic process [GO:1901565]	branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; organonitrogen compound catabolic process [GO:1901565]; response to cadmium ion [GO:0046686]; response to toxic substance [GO:0009636]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plastid [GO:0009536]; thylakoid [GO:0009579]; vacuole [GO:0005773]	deaminase activity [GO:0019239]	deaminase activity [GO:0019239]
d3m4se__d3zo8a___1				Firmicutes	cytosol [GO:0005829]; mitochondrion [GO:0005739]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	organonitrogen compound catabolic process [GO:1901565]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	deaminase activity [GO:0019239]	chorismate mutase activity [GO:0004106]
d3m4sf__d1qd9a___1				Firmicutes	cytosol [GO:0005829]; mitochondrion [GO:0005739]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	cytoplasm [GO:0005737]; deaminase activity [GO:0019239]; 2-oxobutyrate biosynthetic process [GO:0046360]; isoleucine biosynthetic process [GO:0009097]; response to toxic substance [GO:0009636]	organonitrogen compound catabolic process [GO:1901565]	2-oxobutyrate biosynthetic process [GO:0046360]; isoleucine biosynthetic process [GO:0009097]; response to toxic substance [GO:0009636]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	deaminase activity [GO:0019239]	deaminase activity [GO:0019239]
d3m5ba__d3fkca___1	Metazoa	Metazoa	Chordata	Chordata	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270]; negative regulation of transcription by RNA polymerase II [GO:0000122]; transcription by RNA polymerase II [GO:0006366]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; methyl-CpG binding [GO:0008327]; sequence-specific DNA binding [GO:0043565]; intracellular signal transduction [GO:0035556]; negative regulation of transcription, DNA-templated [GO:0045892]; Wnt signaling pathway [GO:0016055]	negative regulation of transcription by RNA polymerase II [GO:0000122]; transcription by RNA polymerase II [GO:0006366]	intracellular signal transduction [GO:0035556]; negative regulation of transcription, DNA-templated [GO:0045892]; Wnt signaling pathway [GO:0016055]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270]	DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; methyl-CpG binding [GO:0008327]; sequence-specific DNA binding [GO:0043565]
d3m5ca2_d3l05a1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]
d3m5da2_d1r0bc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d3m5hc__d4wssd1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3m5he__d3znkc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3m5ia__d5a3ia1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d3m5ie__d1rv0j___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3m5ja__d2fk0g2__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3m5ja__d2wrbc1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3m5jc__d4yy1a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3m5jc__d5e2ze1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3m5la1_d1wykd___1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3m64a__d5jgwb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3m67a__d4cnra___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3m6gb2_d3s41a2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]
d3m6sa1_d3vune___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3m6sc1_d4bgya___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3m6si1_d4m4ya1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3m6sk__d4bsea___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3m79b__d4d4xa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3m79f__d2j9bb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3m79g__d3fook___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3m79h__d5l31d___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3m7ne2_d2c37m2__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasmic exosome (RNase complex) [GO:0000177]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]
d3m7ng1_d2npfa3__1		Fungi	Euryarchaeota	Ascomycota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	maintenance of translational fidelity [GO:1990145]; positive regulation of translational elongation [GO:0045901]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytosol [GO:0005829]; ribonucleoprotein complex [GO:1990904]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosome binding [GO:0043022]; rRNA binding [GO:0019843]; translation elongation factor activity [GO:0003746]
d3m7ng2_d2br2e2__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasmic exosome (RNase complex) [GO:0000177]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]
d3m7nh1_d2b9mi1__1			Euryarchaeota		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]		RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]		cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]		RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	
d3m7ni2_d2wnra2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; 3'-5'-exoribonuclease activity [GO:0000175]; RNA catabolic process [GO:0006401]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	RNA catabolic process [GO:0006401]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]
d3m7wc__d5dbua___1			Proteobacteria	Firmicutes	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]		cytoplasm [GO:0005737]	3-dehydroquinate dehydratase activity [GO:0003855]	deoxyribose-phosphate aldolase activity [GO:0004139]
d3m7wd__d3h5db___1			Proteobacteria		3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]		3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]				3-dehydroquinate dehydratase activity [GO:0003855]	
d3m7wf__d3tdfb___1			Proteobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]	3-dehydroquinate dehydratase activity [GO:0003855]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3m81a__d5a62a___1			Thermotogae	Thaumarchaeota	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]	hydrolase activity [GO:0016787]	cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]		cytoplasm [GO:0005737]		acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]	hydrolase activity [GO:0016787]
d3m81b__d2xlbj___1			Thermotogae	Firmicutes	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]	acetylesterase activity [GO:0008126]	cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]		cytoplasm [GO:0005737]		acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]	acetylesterase activity [GO:0008126]
d3m81d__d2ripa2__1		Metazoa	Thermotogae	Chordata	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3m81f__d3pi6c1__1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]	hydrolase activity [GO:0016787]	cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]		cytoplasm [GO:0005737]		acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]	hydrolase activity [GO:0016787]
d3m85d1_d1udsa1__1			Euryarchaeota	Aquificae	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]		RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d3m85d1_d1y5ya___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; carbon-nitrogen lyase activity [GO:0016840]; carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	carbohydrate biosynthetic process [GO:0016051]; formaldehyde catabolic process [GO:0046294]; one-carbon metabolic process [GO:0006730]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasm [GO:0005737]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	carbon-nitrogen lyase activity [GO:0016840]
d3m85e2_d2ba1h2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3m85e2_d3b4tb2__1			Euryarchaeota	Actinobacteria	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	plasma membrane [GO:0005886]; 3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	plasma membrane [GO:0005886]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d3m85g1_d1ueka1__1			Euryarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity [GO:0050515]; ATP binding [GO:0005524]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]		RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity [GO:0050515]; ATP binding [GO:0005524]
d3m85h2_d2br2g2__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA catabolic process [GO:0016075]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasmic exosome (RNase complex) [GO:0000177]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]
d3m85i1_d1fwla1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]; threonine biosynthetic process [GO:0009088]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	threonine biosynthetic process [GO:0009088]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]	cytoplasm [GO:0005737]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; homoserine kinase activity [GO:0004413]
d3m85i2_d1oypc2__1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]	rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]	cytoplasm [GO:0005737]; exosome (RNase complex) [GO:0000178]		RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d3m8ab__d3r66a___1		Metazoa	Negarnaviricota	Chordata	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; RNA binding [GO:0003723]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	RNA binding [GO:0003723]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3m8ac1_d5by1b___1			Negarnaviricota	Negarnaviricota	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; RNA binding [GO:0003723]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; RNA binding [GO:0003723]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3m8ca__d1oh0a___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	steroid metabolic process [GO:0008202]	steroid metabolic process [GO:0008202]			steroid delta-isomerase activity [GO:0004769]	steroid delta-isomerase activity [GO:0004769]
d3m8cc__d4xdvc___1			Proteobacteria	Actinobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	limonene-1,2-epoxide hydrolase activity [GO:0018744]	steroid metabolic process [GO:0008202]				steroid delta-isomerase activity [GO:0004769]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d3m8oh1_d5iwlb1__1		Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; thrombospondin receptor activity [GO:0070053]; cell migration [GO:0016477]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; neutrophil degranulation [GO:0043312]; opsonization [GO:0008228]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of inflammatory response [GO:0050729]; positive regulation of phagocytosis [GO:0050766]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell activation [GO:0050870]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-10 production [GO:0032653]; regulation of interleukin-12 production [GO:0032655]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]; response to bacterium [GO:0009617]		cell migration [GO:0016477]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis [GO:1905450]; neutrophil degranulation [GO:0043312]; opsonization [GO:0008228]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of inflammatory response [GO:0050729]; positive regulation of phagocytosis [GO:0050766]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell activation [GO:0050870]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-10 production [GO:0032653]; regulation of interleukin-12 production [GO:0032655]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]; response to bacterium [GO:0009617]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		cell-cell adhesion mediator activity [GO:0098632]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; thrombospondin receptor activity [GO:0070053]
d3m8oh2_d3t4yb1__1												
d3m8oh2_d4mngf1__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3m8sa1_d1njza1__1			Deinococcus-Thermus	Firmicutes	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]			DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d3m8ua__d1quia___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	transmembrane transport [GO:0055085]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]		phosphate ion binding [GO:0042301]
d3m8va__d4cp3b1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; methyl-CpG binding [GO:0008327]; sequence-specific DNA binding [GO:0043565]; intracellular signal transduction [GO:0035556]; negative regulation of transcription, DNA-templated [GO:0045892]; Wnt signaling pathway [GO:0016055]	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; intronic transcription regulatory region sequence-specific DNA binding [GO:0001161]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; actin cytoskeleton organization [GO:0030036]; B cell differentiation [GO:0030183]; cell morphogenesis [GO:0000902]; cellular response to DNA damage stimulus [GO:0006974]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte development [GO:0048821]; germinal center formation [GO:0002467]; inflammatory response [GO:0006954]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cellular senescence [GO:2000773]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mitotic cell cycle DNA replication [GO:1903464]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular component movement [GO:0051272]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of germinal center formation [GO:0002634]; regulation of GTPase activity [GO:0043087]; regulation of immune response [GO:0050776]; regulation of inflammatory response [GO:0050727]; regulation of memory T cell differentiation [GO:0043380]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; type 2 immune response [GO:0042092]	intracellular signal transduction [GO:0035556]; negative regulation of transcription, DNA-templated [GO:0045892]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton organization [GO:0030036]; B cell differentiation [GO:0030183]; cell morphogenesis [GO:0000902]; cellular response to DNA damage stimulus [GO:0006974]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte development [GO:0048821]; germinal center formation [GO:0002467]; inflammatory response [GO:0006954]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cell growth [GO:0030308]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mitotic cell cycle DNA replication [GO:1903464]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular component movement [GO:0051272]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of germinal center formation [GO:0002634]; regulation of GTPase activity [GO:0043087]; regulation of immune response [GO:0050776]; regulation of inflammatory response [GO:0050727]; regulation of memory T cell differentiation [GO:0043380]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; type 2 immune response [GO:0042092]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; methyl-CpG binding [GO:0008327]; sequence-specific DNA binding [GO:0043565]	chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; intronic transcription regulatory region sequence-specific DNA binding [GO:0001161]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]
d3m96a__d1zh9a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3m99c__d3fwcl___1	Fungi	Fungi	Ascomycota	Ascomycota	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]; chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]; histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]; chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]; histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]	chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]	chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]
d3m9ja__d2xc2a___1	Metazoa	Metazoa	Chordata	Platyhelminthes	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]
d3m9wa__d1jyea___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; monosaccharide binding [GO:0048029]; D-xylose metabolic process [GO:0042732]; D-xylose transmembrane transport [GO:0015753]	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	D-xylose metabolic process [GO:0042732]; D-xylose transmembrane transport [GO:0015753]	negative regulation of transcription, DNA-templated [GO:0045892]	outer membrane-bounded periplasmic space [GO:0030288]	cytosol [GO:0005829]	monosaccharide binding [GO:0048029]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]
d3m9xa__d1glga___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; monosaccharide binding [GO:0048029]; D-xylose metabolic process [GO:0042732]; D-xylose transmembrane transport [GO:0015753]	outer membrane-bounded periplasmic space [GO:0030288]; metal ion binding [GO:0046872]; chemotaxis [GO:0006935]; galactose transmembrane transport [GO:0015757]; methylgalactoside transport [GO:0015765]	D-xylose metabolic process [GO:0042732]; D-xylose transmembrane transport [GO:0015753]	chemotaxis [GO:0006935]; galactose transmembrane transport [GO:0015757]; methylgalactoside transport [GO:0015765]	outer membrane-bounded periplasmic space [GO:0030288]	outer membrane-bounded periplasmic space [GO:0030288]	monosaccharide binding [GO:0048029]	metal ion binding [GO:0046872]
d3m9za__d1ypof___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]		blood circulation [GO:0008015]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d3ma2d__d2d1oa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; intermediate filament cytoskeleton [GO:0045111]; macropinosome [GO:0044354]; melanosome [GO:0042470]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; metalloaminopeptidase activity [GO:0070006]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; astrocyte cell migration [GO:0043615]; branching morphogenesis of an epithelial tube [GO:0048754]; cell motility [GO:0048870]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; endodermal cell differentiation [GO:0035987]; endothelial cell proliferation [GO:0001935]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; head development [GO:0060322]; lung development [GO:0030324]; male gonad development [GO:0008584]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle development [GO:0001541]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of macrophage migration [GO:1905523]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein processing [GO:0010954]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein localization to plasma membrane [GO:1903076]; response to estrogen [GO:0043627]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to odorant [GO:1990834]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; skeletal system development [GO:0001501]; tissue remodeling [GO:0048771]; zymogen activation [GO:0031638]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	angiogenesis [GO:0001525]; astrocyte cell migration [GO:0043615]; branching morphogenesis of an epithelial tube [GO:0048754]; cell motility [GO:0048870]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; endodermal cell differentiation [GO:0035987]; endothelial cell proliferation [GO:0001935]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; head development [GO:0060322]; lung development [GO:0030324]; male gonad development [GO:0008584]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle development [GO:0001541]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of macrophage migration [GO:1905523]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein processing [GO:0010954]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein localization to plasma membrane [GO:1903076]; response to estrogen [GO:0043627]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to odorant [GO:1990834]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; skeletal system development [GO:0001501]; tissue remodeling [GO:0048771]; zymogen activation [GO:0031638]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; intermediate filament cytoskeleton [GO:0045111]; macropinosome [GO:0044354]; melanosome [GO:0042470]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; metalloaminopeptidase activity [GO:0070006]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3ma4a1_d3csid2__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3ma7b__d3d5of2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d3macl1_d3mlul1__1						viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		viral envelope [GO:0019031]; virion membrane [GO:0055036]		
d3macl2_d3qxvd___1												
d3maea__d4claa___1				Proteobacteria		chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]				chloramphenicol O-acetyltransferase activity [GO:0008811]
d3maka2_d2vcvg2__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; DDT-dehydrochlorinase activity [GO:0018833]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to toxic substance [GO:0009636]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; response to toxic substance [GO:0009636]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	DDT-dehydrochlorinase activity [GO:0018833]; glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d3mama__d2zykc___1			Euryarchaeota	Firmicutes	ATP-binding cassette (ABC) transporter complex [GO:0043190]; metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]	plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]			ATP-binding cassette (ABC) transporter complex [GO:0043190]	plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]	carbohydrate transmembrane transporter activity [GO:0015144]
d3mb3a__d4a9ha___1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; insulin receptor binding [GO:0005158]; lysine-acetylated histone binding [GO:0070577]; cytoskeleton organization [GO:0007010]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	cytoskeleton organization [GO:0007010]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	insulin receptor binding [GO:0005158]; lysine-acetylated histone binding [GO:0070577]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]
d3mbaa__d4l1ea___1	Metazoa		Mollusca	Cyanobacteria	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3mbfa__d1xfbc___1	Fungi	Metazoa	Microsporidia	Chordata	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]; canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	fructose-bisphosphate aldolase activity [GO:0004332]	cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]
d3mbga__d1jr8a___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	fungal-type vacuole [GO:0000324]; fungal-type vacuole membrane [GO:0000329]; integral component of endoplasmic reticulum membrane [GO:0030176]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	fungal-type vacuole [GO:0000324]; fungal-type vacuole membrane [GO:0000329]; integral component of endoplasmic reticulum membrane [GO:0030176]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]
d3mbgc__d3w4yc1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	cell [GO:0005623]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; protein import into mitochondrial intermembrane space [GO:0045041]		cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; protein import into mitochondrial intermembrane space [GO:0045041]	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	cell [GO:0005623]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]
d3mbib1_d1bd3d___1			Euryarchaeota	Apicomplexa	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]; nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	nucleoside metabolic process [GO:0009116]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]	GTP binding [GO:0005525]; uracil phosphoribosyltransferase activity [GO:0004845]
d3mbic1_d4mb6a___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	cytoplasm [GO:0005737]; adenine phosphoribosyltransferase activity [GO:0003999]; adenine salvage [GO:0006168]; AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	adenine salvage [GO:0006168]; AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]	adenine phosphoribosyltransferase activity [GO:0003999]
d3mbma__d1iv1c___1			Proteobacteria	Deinococcus-Thermus	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d3mbqb__d2we2a2__1			Proteobacteria		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP metabolic process [GO:0046080]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]
d3mbta__d4orra___1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; cytoplasm [GO:0005737]; lipid binding [GO:0008289]; cellular response to DNA damage stimulus [GO:0006974]; lipid metabolic process [GO:0006629]; response to reactive oxygen species [GO:0000302]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	cellular response to DNA damage stimulus [GO:0006974]; lipid metabolic process [GO:0006629]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	cell outer membrane [GO:0009279]; cytoplasm [GO:0005737]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	lipid binding [GO:0008289]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d3mc0a__d1xiwh___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	extracellular region [GO:0005576]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]
d3mc0c__d1dclb2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	pathogenesis [GO:0009405]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d3mc0d2_d3r8bi2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	pathogenesis [GO:0009405]		extracellular region [GO:0005576]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d3mcg12_d1wiqa2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3mcg12_d5wt9l2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]	
d3mcg22_d6azze2__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]	
d3mchb__d2nqna3__1			Deinococcus-Thermus	Proteobacteria	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d3mcjc__d1g8rb3__1			Aquificae	Proteobacteria	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d3mcka2_d5f6hp2__1												
d3mcka2_d5t93a___1												
d3mcll1_d2pyfb2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3mcyd__d1qunf2__1			Proteobacteria	Proteobacteria	pilus [GO:0009289]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]	metal ion binding [GO:0046872]	mannose binding [GO:0005537]
d3md1a1_d4zkaa___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleus [GO:0005634]; P-body [GO:0000932]; mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of mRNA stability [GO:0043488]; stress granule assembly [GO:0034063]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; trans-Golgi network [GO:0005802]; mRNA binding [GO:0003729]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]; mRNA processing [GO:0006397]; nervous system development [GO:0007399]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; RNA transport [GO:0050658]	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of mRNA stability [GO:0043488]; stress granule assembly [GO:0034063]	mRNA processing [GO:0006397]; nervous system development [GO:0007399]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; RNA transport [GO:0050658]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleus [GO:0005634]; P-body [GO:0000932]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; trans-Golgi network [GO:0005802]	mRNA binding [GO:0003729]; poly(U) RNA binding [GO:0008266]	mRNA binding [GO:0003729]; protein C-terminus binding [GO:0008022]; RNA binding [GO:0003723]
d3mdea1_d1ws9a1__1	Metazoa		Chordata	Deinococcus-Thermus	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d3mdea1_d3mpib2__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; aromatic compound catabolic process [GO:0019439]	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]	aromatic compound catabolic process [GO:0019439]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d3mdeb1_d3mkhc2__1	Metazoa	Fungi	Chordata	Ascomycota	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]	flavin adenine dinucleotide binding [GO:0050660]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]	flavin adenine dinucleotide binding [GO:0050660]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d3mdjb1_d3fuea1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; aminopeptidase activity [GO:0004177]; interleukin-1, type II receptor binding [GO:0005151]; interleukin-6 receptor binding [GO:0005138]; metalloaminopeptidase activity [GO:0070006]; metalloexopeptidase activity [GO:0008235]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; fat cell differentiation [GO:0045444]; membrane protein ectodomain proteolysis [GO:0006509]; peptide catabolic process [GO:0043171]; positive regulation of angiogenesis [GO:0045766]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of innate immune response [GO:0045088]; response to bacterium [GO:0009617]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; fat cell differentiation [GO:0045444]; membrane protein ectodomain proteolysis [GO:0006509]; peptide catabolic process [GO:0043171]; positive regulation of angiogenesis [GO:0045766]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of innate immune response [GO:0045088]; response to bacterium [GO:0009617]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	aminopeptidase activity [GO:0004177]; interleukin-1, type II receptor binding [GO:0005151]; interleukin-6 receptor binding [GO:0005138]; metalloaminopeptidase activity [GO:0070006]; metalloexopeptidase activity [GO:0008235]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3mdsa1_d2bkba1__1			Deinococcus-Thermus	Proteobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to superoxide [GO:0000303]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]
d3mdsa1_d2rcvf1__1			Deinococcus-Thermus	Firmicutes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3mdsa2_d2rcvd2__1			Deinococcus-Thermus	Firmicutes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]				cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3mebb__d2vgta___1				Firmicutes	mitochondrion [GO:0005739]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]; glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]	glycine biosynthetic process from serine [GO:0019264]; tetrahydrofolate interconversion [GO:0035999]	mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]	glycine hydroxymethyltransferase activity [GO:0004372]; pyridoxal phosphate binding [GO:0030170]
d3meza__d5t20o___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]						mannose binding [GO:0005537]	
d3mezd__d1msac___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]	extracellular region [GO:0005576]; mannose binding [GO:0005537]				extracellular region [GO:0005576]	mannose binding [GO:0005537]	mannose binding [GO:0005537]
d3mezd__d5t20i___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	mannose binding [GO:0005537]						mannose binding [GO:0005537]	
d3mf3c__d3tenh___1			Proteobacteria	Crenarchaeota	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbonate dehydratase activity [GO:0004089]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; hydrogen sulfide biosynthetic process [GO:0070814]	carbon utilization [GO:0015976]	hydrogen sulfide biosynthetic process [GO:0070814]			carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d3mf3c__d5cxkh___1			Proteobacteria	Proteobacteria	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	carbon utilization [GO:0015976]	carbon utilization [GO:0015976]			carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3mfec__d4qv8u___1		Fungi	Actinobacteria	Ascomycota	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mfee__d5l66v___1		Fungi	Actinobacteria	Ascomycota	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mfeh__d3tddu___1		Fungi	Actinobacteria	Ascomycota	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mfer__d4qz2c___1		Fungi	Actinobacteria	Ascomycota	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mffa1_d3tlra1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3mffb1_d1it9l2__1												
d3mffb2_d3m8ol1__1												
d3mffd2_d1cf8h2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3mfja__d3su4a___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3mfmb1_d2zl3d___1			Actinobacteria	Proteobacteria	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	fatty acid biosynthetic process [GO:0006633]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	acetyl-CoA carboxylase complex [GO:0009317]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d3mfmc1_d1o8uc___1			Actinobacteria	Actinobacteria	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	fatty acid biosynthetic process [GO:0006633]		acetyl-CoA carboxylase complex [GO:0009317]		acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]
d3mfmd1_d1szok___1			Actinobacteria	Actinobacteria	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	fatty acid biosynthetic process [GO:0006633]		acetyl-CoA carboxylase complex [GO:0009317]		acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]
d3mfmd2_d2zl0i___1			Actinobacteria	Proteobacteria	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	fatty acid biosynthetic process [GO:0006633]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	acetyl-CoA carboxylase complex [GO:0009317]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d3mfqc__d5cx1l___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]	metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d3mfvb__d4ie3c___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d3mfvb__d5eena___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]
d3mfwb__d1c3sa___1	Metazoa		Chordata	Aquificae	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	metal ion binding [GO:0046872]; acetoin metabolic process [GO:0045149]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	acetoin metabolic process [GO:0045149]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	metal ion binding [GO:0046872]
d3mg3b2_d3zg5a1__1			Cyanobacteria	Firmicutes	phycobilisome [GO:0030089]; chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]; light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	response to antibiotic [GO:0046677]	phycobilisome [GO:0030089]	integral component of membrane [GO:0016021]	chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]	penicillin binding [GO:0008658]
d3mg4c__d4nnwg___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mg4h__d4qv8a___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mg4m__d3unbe___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mg4u__d4inrk___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mg4u__d5l63s___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mg4w__d5l5vs___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mg4z__d1g0uy___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mg5a__d3ry2a___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3mg7k__d4qvvn___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mgha1_d3uxnb1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d3mghc1_d2fmsa1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d3mghc3_d4k4ia3__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d3mgka__d1kxja1__1			Firmicutes	Thermotogae	peptidase activity [GO:0008233]	cytoplasm [GO:0005737]; glutaminase activity [GO:0004359]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; glutamine metabolic process [GO:0006541]; histidine biosynthetic process [GO:0000105]		glutamine metabolic process [GO:0006541]; histidine biosynthetic process [GO:0000105]		cytoplasm [GO:0005737]	peptidase activity [GO:0008233]	glutaminase activity [GO:0004359]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]
d3mgob1_d4k3hb___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3mgok1_d4lf3a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; G protein-coupled peptide receptor activity [GO:0008528]; glucagon receptor activity [GO:0004967]; guanyl-nucleotide exchange factor activity [GO:0005085]; peptide hormone binding [GO:0017046]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glucagon stimulus [GO:0071377]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; regulation of blood pressure [GO:0008217]; regulation of glycogen metabolic process [GO:0070873]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glucagon stimulus [GO:0071377]; exocytosis [GO:0006887]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; G protein-coupled receptor signaling pathway [GO:0007186]; hormone-mediated signaling pathway [GO:0009755]; regulation of blood pressure [GO:0008217]; regulation of glycogen metabolic process [GO:0070873]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	glucagon receptor activity [GO:0004967]; G protein-coupled peptide receptor activity [GO:0008528]; guanyl-nucleotide exchange factor activity [GO:0005085]; peptide hormone binding [GO:0017046]
d3mgph__d5b0zf___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3mgqb__d1s32c___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3mgrd__d4wnnh___1	Metazoa	Fungi	Chordata	Ascomycota	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nuclear nucleosome [GO:0000788]; replication fork protection complex [GO:0031298]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin assembly or disassembly [GO:0006333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334]; postreplication repair [GO:0006301]		chromatin assembly or disassembly [GO:0006333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome assembly [GO:0006334]; postreplication repair [GO:0006301]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nuclear nucleosome [GO:0000788]; replication fork protection complex [GO:0031298]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3mgre__d1zbbf1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3mgtb1_d1vadb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3mgte1_d3tzvg1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3mgth1_d1kt2c1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3mgth1_d5u17g1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3mh9c1_d2w7qa___1			Actinobacteria	Proteobacteria	bacterial extracellular vesicle [GO:0097691]; cell surface [GO:0009986]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; glycolipid binding [GO:0051861]; phosphatidylinositol binding [GO:0035091]; lipid transport [GO:0006869]; pathogenesis [GO:0009405]; response to antibiotic [GO:0046677]	outer membrane-bounded periplasmic space [GO:0030288]; chaperone-mediated protein transport across periplasmic space [GO:0072323]; lipoprotein localization to outer membrane [GO:0044874]; lipoprotein transport [GO:0042953]	lipid transport [GO:0006869]; pathogenesis [GO:0009405]; response to antibiotic [GO:0046677]	chaperone-mediated protein transport across periplasmic space [GO:0072323]; lipoprotein localization to outer membrane [GO:0044874]; lipoprotein transport [GO:0042953]	bacterial extracellular vesicle [GO:0097691]; cell surface [GO:0009986]; cell wall [GO:0005618]; plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]	glycolipid binding [GO:0051861]; phosphatidylinositol binding [GO:0035091]	
d3mhab1_d4qa8a___1			Actinobacteria	Actinobacteria	bacterial extracellular vesicle [GO:0097691]; cell surface [GO:0009986]; cell wall [GO:0005618]; plasma membrane [GO:0005886]; glycolipid binding [GO:0051861]; phosphatidylinositol binding [GO:0035091]; lipid transport [GO:0006869]; pathogenesis [GO:0009405]; response to antibiotic [GO:0046677]	plasma membrane [GO:0005886]; lipid binding [GO:0008289]; lipid transport [GO:0006869]	lipid transport [GO:0006869]; pathogenesis [GO:0009405]; response to antibiotic [GO:0046677]	lipid transport [GO:0006869]	bacterial extracellular vesicle [GO:0097691]; cell surface [GO:0009986]; cell wall [GO:0005618]; plasma membrane [GO:0005886]	plasma membrane [GO:0005886]	glycolipid binding [GO:0051861]; phosphatidylinositol binding [GO:0035091]	lipid binding [GO:0008289]
d3mheb__d4hm6b___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]	steroid metabolic process [GO:0008202]	aromatic compound catabolic process [GO:0019439]			steroid delta-isomerase activity [GO:0004769]	dioxygenase activity [GO:0051213]
d3mhma__d1th9a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3mhma__d4uova___1	Metazoa		Chordata	Aquificae	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3mhyc__d2xunh___1			Proteobacteria		ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]		regulation of nitrogen utilization [GO:0006808]				ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]	
d3mica2_d1pnga1__1	Metazoa		Chordata	Bacteroidetes	cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]; central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]	central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]		cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]
d3miga1_d3mlja2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]; central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]	cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]; central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]	central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]	central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]	cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]	cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]
d3miha1_d3pmsa2__1	Metazoa		Chordata	Bacteroidetes	cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]; central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]	central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]		cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]
d3mima__d4z50b___1						aspartic-type endopeptidase activity [GO:0004190]						aspartic-type endopeptidase activity [GO:0004190]
d3minb__d5y8ab1__1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	
d3miqf__d1nfdg1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3miqh1_d1gm3h1__1												
d3miqh1_d5ihzb2__1												
d3mita__d1xxrc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d3miua__d2bmzb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d3miub__d1c3ma___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d3mj8a1_d2x4re1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3mj8a1_d5fyje1__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d3mj8l1_d1za6c1__1		Metazoa		Chordata								
d3mj9l1_d1fc1b1__1	Metazoa	Metazoa	Chordata	Chordata	bicellular tight junction [GO:0005923]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; protein homodimerization activity [GO:0042803]; gamma-delta T cell activation [GO:0046629]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; monocyte extravasation [GO:0035696]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	gamma-delta T cell activation [GO:0046629]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; monocyte extravasation [GO:0035696]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	bicellular tight junction [GO:0005923]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3mj9l2_d2q1ea___1	Metazoa	Metazoa	Chordata	Chordata	bicellular tight junction [GO:0005923]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; protein homodimerization activity [GO:0042803]; gamma-delta T cell activation [GO:0046629]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; monocyte extravasation [GO:0035696]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]		gamma-delta T cell activation [GO:0046629]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; monocyte extravasation [GO:0035696]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]		bicellular tight junction [GO:0005923]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; protein homodimerization activity [GO:0042803]	
d3mjia__d3mg4d___1		Fungi	Firmicutes	Ascomycota	penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	penicillin amidase activity [GO:0008953]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mjib__d4qv0t___1		Fungi	Firmicutes	Ascomycota	penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	penicillin amidase activity [GO:0008953]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3mjob__d3e6rd___1			Actinobacteria	Bacillariophyta (diatoms)	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]
d3mjpc__d109ma___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3mjzc__d4wr8i___1		Metazoa	Actinobacteria	Chordata		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d3mk6a2_d3r6mc2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nucleus [GO:0005634]; acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]; coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]	
d3mk6b2_d5aqia2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]; coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3mkba__d1g0ba___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3mkha2_d2zafa1__1	Fungi	Fungi	Ascomycota	Ascomycota	flavin adenine dinucleotide binding [GO:0050660]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]		nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]			flavin adenine dinucleotide binding [GO:0050660]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d3mkia__d2f86l___1		Metazoa	Proteobacteria	Nematoda (roundworms)	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]	steroid metabolic process [GO:0008202]	MAPK cascade [GO:0000165]; medium-term memory [GO:0072375]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]		axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	steroid delta-isomerase activity [GO:0004769]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d3mkid__d5stda1__1		Fungi	Proteobacteria	Ascomycota	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	endosome [GO:0005768]; metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]; melanin biosynthetic process [GO:0042438]	steroid metabolic process [GO:0008202]	melanin biosynthetic process [GO:0042438]		endosome [GO:0005768]	steroid delta-isomerase activity [GO:0004769]	metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]
d3mksc2_d5hywd___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	CBF3 complex [GO:0031518]; cell [GO:0005623]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; kinetochore [GO:0000776]; nucleus [GO:0005634]; RAVE complex [GO:0043291]; SCF ubiquitin ligase complex [GO:0019005]; cullin family protein binding [GO:0097602]; DNA replication origin binding [GO:0003688]; cellular protein-containing complex assembly [GO:0034622]; exit from mitosis [GO:0010458]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; kinetochore assembly [GO:0051382]; mitotic cell cycle [GO:0000278]; negative regulation of cytoplasmic translation [GO:2000766]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; regulation of exit from mitosis [GO:0007096]; regulation of protein complex assembly [GO:0043254]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; septin ring assembly [GO:0000921]; ubiquitin-dependent protein catabolic process [GO:0006511]; vacuolar acidification [GO:0007035]	nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; auxin polar transport [GO:0009926]; cuticle development [GO:0042335]; multicellular organism development [GO:0007275]; negative regulation of seed germination [GO:0010187]; positive regulation of response to water deprivation [GO:1902584]; protein ubiquitination [GO:0016567]; regulation of meristem structural organization [GO:0009934]; regulation of shoot system morphogenesis [GO:1900618]; response to light stimulus [GO:0009416]; response to water deprivation [GO:0009414]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; shoot system morphogenesis [GO:0010016]; ubiquitin-dependent protein catabolic process [GO:0006511]	cellular protein-containing complex assembly [GO:0034622]; exit from mitosis [GO:0010458]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; kinetochore assembly [GO:0051382]; mitotic cell cycle [GO:0000278]; negative regulation of cytoplasmic translation [GO:2000766]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; regulation of exit from mitosis [GO:0007096]; regulation of protein complex assembly [GO:0043254]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; septin ring assembly [GO:0000921]; ubiquitin-dependent protein catabolic process [GO:0006511]; vacuolar acidification [GO:0007035]	auxin polar transport [GO:0009926]; cuticle development [GO:0042335]; multicellular organism development [GO:0007275]; negative regulation of seed germination [GO:0010187]; positive regulation of response to water deprivation [GO:1902584]; protein ubiquitination [GO:0016567]; regulation of meristem structural organization [GO:0009934]; regulation of shoot system morphogenesis [GO:1900618]; response to light stimulus [GO:0009416]; response to water deprivation [GO:0009414]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; shoot system morphogenesis [GO:0010016]; ubiquitin-dependent protein catabolic process [GO:0006511]	CBF3 complex [GO:0031518]; cell [GO:0005623]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; kinetochore [GO:0000776]; nucleus [GO:0005634]; RAVE complex [GO:0043291]; SCF ubiquitin ligase complex [GO:0019005]	nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	cullin family protein binding [GO:0097602]; DNA replication origin binding [GO:0003688]	
d3ml1a2_d1kqga1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	formate dehydrogenase complex [GO:0009326]; membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (cytochrome-c-553) activity [GO:0047111]; formate dehydrogenase (NAD+) activity [GO:0008863]; formate dehydrogenase (quinone) activity [GO:0036397]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; selenium binding [GO:0008430]; anaerobic respiration [GO:0009061]; formate oxidation [GO:0015944]	anaerobic respiration [GO:0009061]	anaerobic respiration [GO:0009061]; formate oxidation [GO:0015944]	periplasmic space [GO:0042597]	formate dehydrogenase complex [GO:0009326]; membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; formate dehydrogenase (cytochrome-c-553) activity [GO:0047111]; formate dehydrogenase (NAD+) activity [GO:0008863]; formate dehydrogenase (quinone) activity [GO:0036397]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; selenium binding [GO:0008430]
d3ml5a__d4e3ha___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of chloride transport [GO:2001225]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of chloride transport [GO:2001225]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cell [GO:0005623]; cytosol [GO:0005829]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3mlaa__d1vlhd___1			Firmicutes	Thermotogae	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	NAD biosynthetic process [GO:0009435]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d3mlce__d5bsjc___1		Metazoa	Actinobacteria	Chordata		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d3mlrl1_d5t0yb2__1					viral envelope [GO:0019031]; virion membrane [GO:0055036]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; virion attachment to host cell [GO:0019062]		viral envelope [GO:0019031]; virion membrane [GO:0055036]			
d3mlsm1_d1y18l2__1												
d3mlsm2_d4yhib2__1												
d3mlsn1_d4aj0b___1												
d3mlsn2_d2aj3a1__1												
d3mlso1_d2jccf2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3mlta2_d4l3cq2__1		Metazoa		Chordata	viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3mltg2_d1n64h2__1					viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3mltl2_d5w3mg___1					viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		viral envelope [GO:0019031]; virion membrane [GO:0055036]			
d3mlul1_d1zglv1__1		Metazoa		Chordata	viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	viral envelope [GO:0019031]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3mlvl1_d3stbb1__1					integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	kinetoplast [GO:0020023]; mitochondrion [GO:0005739]; 3'-5'-exoribonuclease activity [GO:0000175]; endoribonuclease activity, producing 5'-phosphomonoesters [GO:0016891]; nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]; mRNA modification [GO:0016556]; response to metal ion [GO:0010038]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	mRNA modification [GO:0016556]; response to metal ion [GO:0010038]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	kinetoplast [GO:0020023]; mitochondrion [GO:0005739]	structural molecule activity [GO:0005198]	3'-5'-exoribonuclease activity [GO:0000175]; endoribonuclease activity, producing 5'-phosphomonoesters [GO:0016891]; nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]
d3mlvl1_d4ttdd1__1		Metazoa		Chordata	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	structural molecule activity [GO:0005198]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3mlvl2_d4at6i2__1					integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d3mlvm2_d2gfbo2__1					integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d3mlwl1_d2ih3b2__1				Actinobacteria	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	voltage-gated potassium channel complex [GO:0008076]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d3mlwl2_d1nmbl___1				Negarnaviricota	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3mlwm1_d5nmdb2__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	
d3mlxl1_d1bfoh2__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3mlxl2_d4qt5a2__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	
d3mlxm2_d1igjc2__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]	
d3mlym2_d4pj7b___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3mlzl2_d1fvdc1__1					viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		viral envelope [GO:0019031]; virion membrane [GO:0055036]			
d3mm5a1_d3b0la1__1		Viridiplantae	Euryarchaeota	Streptophyta	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3mm6d1_d3b0ja3__1		Viridiplantae	Euryarchaeota	Streptophyta	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3mm6e3_d1vler2__1			Euryarchaeota		membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]		sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	
d3mm8b1_d3mm7d1__1			Euryarchaeota	Euryarchaeota	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	sulfur compound metabolic process [GO:0006790]	sulfur compound metabolic process [GO:0006790]	membrane [GO:0016020]	membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d3mm8e1_d3b0ha1__1		Viridiplantae	Euryarchaeota	Streptophyta	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3mm9a1_d3vm0a3__1		Viridiplantae	Euryarchaeota	Streptophyta	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3mm9b1_d3b0na3__1		Viridiplantae	Euryarchaeota	Streptophyta	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3mm9e1_d3vkra3__1		Viridiplantae	Euryarchaeota	Streptophyta	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3mmaa1_d3b0hb1__1		Viridiplantae	Euryarchaeota	Streptophyta	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3mmad1_d3mm7e1__1			Euryarchaeota	Euryarchaeota	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	sulfur compound metabolic process [GO:0006790]	sulfur compound metabolic process [GO:0006790]	membrane [GO:0016020]	membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d3mmba1_d2aopa2__1			Euryarchaeota	Proteobacteria	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	sulfite reductase complex (NADPH) [GO:0009337]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	sulfur compound metabolic process [GO:0006790]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	membrane [GO:0016020]	sulfite reductase complex (NADPH) [GO:0009337]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]
d3mmbd1_d2v4ja2__1			Euryarchaeota	Proteobacteria	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	sulfur compound metabolic process [GO:0006790]	sulfur compound metabolic process [GO:0006790]	membrane [GO:0016020]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d3mmbe1_d3vksa1__1		Viridiplantae	Euryarchaeota	Streptophyta	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3mmca2_d1zj9b1__1			Euryarchaeota	Actinobacteria	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	cell wall [GO:0005618]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]	sulfur compound metabolic process [GO:0006790]	cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]	membrane [GO:0016020]	cell wall [GO:0005618]; cytosol [GO:0005829]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]
d3mmcb2_d3b0ja1__1		Viridiplantae	Euryarchaeota	Streptophyta	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]		4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3mmce2_d1aopa2__1			Euryarchaeota	Proteobacteria	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	sulfite reductase complex (NADPH) [GO:0009337]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	sulfur compound metabolic process [GO:0006790]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	membrane [GO:0016020]	sulfite reductase complex (NADPH) [GO:0009337]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]
d3mmda__d3wq4a___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102402]; beta-primeverosidase activity [GO:0050535]; linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102404]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102402]; beta-primeverosidase activity [GO:0050535]; linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102404]
d3mmha__d3c2wf1__1				Proteobacteria		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]				ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3mmja__d2b4oa___1			Firmicutes	Firmicutes	protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]					protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d3mmtd1_d3flub___1			Proteobacteria	Proteobacteria	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycolytic process [GO:0006096]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3mmtd1_d3s1vb___1			Proteobacteria	Euryarchaeota	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]	fructose-bisphosphate aldolase activity [GO:0004332]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d3mmub__d3ptka___1		Viridiplantae	Thermotogae	Streptophyta	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	extracellular region [GO:0005576]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]
d3mmuc__d5uhxa1__1			Thermotogae		extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]		cellular glucan metabolic process [GO:0006073]		extracellular region [GO:0005576]		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	
d3mmue__d3aiva___1		Viridiplantae	Thermotogae	Streptophyta	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	chloroplast [GO:0009507]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-glucosidase activity [GO:0008422]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; scopolin beta-glucosidase activity [GO:0102483]
d3mmuf__d3gxma2__1		Metazoa	Thermotogae	Chordata	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	cellular glucan metabolic process [GO:0006073]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular region [GO:0005576]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d3mmwc__d1b1ya___1		Viridiplantae	Thermotogae	Streptophyta	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; identical protein binding [GO:0042802]; polysaccharide catabolic process [GO:0000272]	cellular glucan metabolic process [GO:0006073]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; identical protein binding [GO:0042802]
d3mmwd__d3f5lb___1		Viridiplantae	Thermotogae	Streptophyta	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d3mmwd__d4toqc___1		Viridiplantae	Thermotogae	Streptophyta	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	amyloplast [GO:0009501]; calcium ion binding [GO:0005509]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]; seed germination [GO:0009845]; seedling development [GO:0090351]	cellular glucan metabolic process [GO:0006073]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]; seed germination [GO:0009845]; seedling development [GO:0090351]	extracellular region [GO:0005576]	amyloplast [GO:0009501]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	calcium ion binding [GO:0005509]; chitinase activity [GO:0004568]
d3mmxb__d3kt8c___1		Fungi	Firmicutes	Ascomycota	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	NAD biosynthetic process [GO:0009435]	tryptophanyl-tRNA aminoacylation [GO:0006436]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d3mn1b1_d1rlma___1			Proteobacteria	Proteobacteria	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	lipopolysaccharide biosynthetic process [GO:0009103]			cytosol [GO:0005829]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]
d3mn1d1_d2r8ya___1			Proteobacteria	Proteobacteria	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]			3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d3mn1k1_d5akha1__1		Metazoa	Proteobacteria	Chordata	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipopolysaccharide biosynthetic process [GO:0009103]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3mn5a2_d3iuca2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3mn6a2_d2q1na2__1	Metazoa	Metazoa	Arthropoda	Chordata	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; microtubule binding [GO:0008017]; actin cytoskeleton organization [GO:0030036]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; actin filament-based process [GO:0030029]; actin nucleation [GO:0045010]; chorion-containing eggshell formation [GO:0007304]; oocyte karyosome formation [GO:0030717]; oogenesis [GO:0048477]; pole plasm assembly [GO:0007315]; pole plasm oskar mRNA localization [GO:0045451]; pole plasm RNA localization [GO:0007316]; protein transport [GO:0015031]; regulation of cytoskeleton organization [GO:0051493]; vesicle-mediated transport [GO:0016192]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cytoskeleton organization [GO:0030036]; actin filament-based process [GO:0030029]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; actin nucleation [GO:0045010]; chorion-containing eggshell formation [GO:0007304]; oocyte karyosome formation [GO:0030717]; oogenesis [GO:0048477]; pole plasm assembly [GO:0007315]; pole plasm oskar mRNA localization [GO:0045451]; pole plasm RNA localization [GO:0007316]; protein transport [GO:0015031]; regulation of cytoskeleton organization [GO:0051493]; vesicle-mediated transport [GO:0016192]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin binding [GO:0003779]; microtubule binding [GO:0008017]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3mn6f2_d3wxla1__1	Metazoa		Arthropoda		cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; microtubule binding [GO:0008017]; actin cytoskeleton organization [GO:0030036]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; actin filament-based process [GO:0030029]; actin nucleation [GO:0045010]; chorion-containing eggshell formation [GO:0007304]; oocyte karyosome formation [GO:0030717]; oogenesis [GO:0048477]; pole plasm assembly [GO:0007315]; pole plasm oskar mRNA localization [GO:0045451]; pole plasm RNA localization [GO:0007316]; protein transport [GO:0015031]; regulation of cytoskeleton organization [GO:0051493]; vesicle-mediated transport [GO:0016192]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin cytoskeleton organization [GO:0030036]; actin filament-based process [GO:0030029]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; actin nucleation [GO:0045010]; chorion-containing eggshell formation [GO:0007304]; oocyte karyosome formation [GO:0030717]; oogenesis [GO:0048477]; pole plasm assembly [GO:0007315]; pole plasm oskar mRNA localization [GO:0045451]; pole plasm RNA localization [GO:0007316]; protein transport [GO:0015031]; regulation of cytoskeleton organization [GO:0051493]; vesicle-mediated transport [GO:0016192]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]		actin binding [GO:0003779]; microtubule binding [GO:0008017]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d3mn7a2_d1yaga2__1	Metazoa	Metazoa	Arthropoda	Chordata	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; microtubule binding [GO:0008017]; actin cytoskeleton organization [GO:0030036]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; actin filament-based process [GO:0030029]; actin nucleation [GO:0045010]; chorion-containing eggshell formation [GO:0007304]; oocyte karyosome formation [GO:0030717]; oogenesis [GO:0048477]; pole plasm assembly [GO:0007315]; pole plasm oskar mRNA localization [GO:0045451]; pole plasm RNA localization [GO:0007316]; protein transport [GO:0015031]; regulation of cytoskeleton organization [GO:0051493]; vesicle-mediated transport [GO:0016192]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin cytoskeleton organization [GO:0030036]; actin filament-based process [GO:0030029]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; actin nucleation [GO:0045010]; chorion-containing eggshell formation [GO:0007304]; oocyte karyosome formation [GO:0030717]; oogenesis [GO:0048477]; pole plasm assembly [GO:0007315]; pole plasm oskar mRNA localization [GO:0045451]; pole plasm RNA localization [GO:0007316]; protein transport [GO:0015031]; regulation of cytoskeleton organization [GO:0051493]; vesicle-mediated transport [GO:0016192]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin binding [GO:0003779]; microtubule binding [GO:0008017]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d3mn9a2_d3djcl1__1	Metazoa		Arthropoda	Proteobacteria	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; microtubule binding [GO:0008017]; actin cytoskeleton organization [GO:0030036]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; actin filament-based process [GO:0030029]; actin nucleation [GO:0045010]; chorion-containing eggshell formation [GO:0007304]; oocyte karyosome formation [GO:0030717]; oogenesis [GO:0048477]; pole plasm assembly [GO:0007315]; pole plasm oskar mRNA localization [GO:0045451]; pole plasm RNA localization [GO:0007316]; protein transport [GO:0015031]; regulation of cytoskeleton organization [GO:0051493]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	actin cytoskeleton organization [GO:0030036]; actin filament-based process [GO:0030029]; actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; actin nucleation [GO:0045010]; chorion-containing eggshell formation [GO:0007304]; oocyte karyosome formation [GO:0030717]; oogenesis [GO:0048477]; pole plasm assembly [GO:0007315]; pole plasm oskar mRNA localization [GO:0045451]; pole plasm RNA localization [GO:0007316]; protein transport [GO:0015031]; regulation of cytoskeleton organization [GO:0051493]; vesicle-mediated transport [GO:0016192]	coenzyme A biosynthetic process [GO:0015937]	cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	actin binding [GO:0003779]; microtubule binding [GO:0008017]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d3mndb__d2zowa___1	Metazoa	Metazoa	Platyhelminthes	Chordata	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]		activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d3mnne__d3azje___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3mnnf__d1bh9b___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; transcription factor TFIID complex [GO:0005669]; protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; thyroid hormone receptor binding [GO:0046966]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; vitamin D receptor binding [GO:0042809]; positive regulation by host of viral transcription [GO:0043923]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]		positive regulation by host of viral transcription [GO:0043923]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; transcription factor TFIID complex [GO:0005669]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	protein heterodimerization activity [GO:0046982]; protein N-terminus binding [GO:0047485]; thyroid hormone receptor binding [GO:0046966]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; vitamin D receptor binding [GO:0042809]
d3mnsa__d1zsja___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d3mnva1_d1jnhb2__1		Metazoa		Chordata		plasma membrane [GO:0005886]				plasma membrane [GO:0005886]		
d3mnva1_d3rtqc1__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3mnvc2_d3wkmm2__1				Aquificae		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]				integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3mo1a2_d4nx3a3__1												
d3mo3a__d3ea9a___1	Metazoa		Chordata		extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3mon.5_d1rn7a___1	Viridiplantae	Metazoa	Streptophyta	Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cysteine-type endopeptidase inhibitor activity [GO:0004869]				extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		cysteine-type endopeptidase inhibitor activity [GO:0004869]
d3moob__d1wnva___1			Actinobacteria	Actinobacteria	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]; heme oxidation [GO:0006788]	heme oxidation [GO:0006788]	heme oxidation [GO:0006788]			heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]	heme oxygenase (decyclizing) activity [GO:0004392]; metal ion binding [GO:0046872]
d3morb__d4guzd1__1				Actinobacteria	cysteine-type peptidase activity [GO:0008234]; posttranscriptional regulation of gene expression [GO:0010608]	acetyltransferase activity [GO:0016407]	posttranscriptional regulation of gene expression [GO:0010608]				cysteine-type peptidase activity [GO:0008234]	acetyltransferase activity [GO:0016407]
d3moya__d3tdca1__1		Metazoa	Actinobacteria	Chordata	enoyl-CoA hydratase activity [GO:0004300]	cytosol [GO:0005829]; endomembrane system [GO:0012505]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin binding [GO:0009374]; biotin carboxylase activity [GO:0004075]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; acetyl-CoA metabolic process [GO:0006084]; carnitine shuttle [GO:0006853]; energy homeostasis [GO:0097009]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of catalytic activity [GO:0043086]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; positive regulation of cellular metabolic process [GO:0031325]; positive regulation of heart growth [GO:0060421]; positive regulation of lipid storage [GO:0010884]; protein homotetramerization [GO:0051289]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of glucose metabolic process [GO:0010906]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]		acetyl-CoA metabolic process [GO:0006084]; carnitine shuttle [GO:0006853]; energy homeostasis [GO:0097009]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of catalytic activity [GO:0043086]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; positive regulation of cellular metabolic process [GO:0031325]; positive regulation of heart growth [GO:0060421]; positive regulation of lipid storage [GO:0010884]; protein homotetramerization [GO:0051289]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of glucose metabolic process [GO:0010906]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]		cytosol [GO:0005829]; endomembrane system [GO:0012505]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	enoyl-CoA hydratase activity [GO:0004300]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin binding [GO:0009374]; biotin carboxylase activity [GO:0004075]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3moza__d3qkqa___1		Metazoa	Firmicutes	Chordata	protein tyrosine phosphatase activity [GO:0004725]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]		actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]		cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3mpda__d2az3f___1	Fungi		Microsporidia	Euryarchaeota	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3mpea__d2fe8a2__1						cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]		cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3mpia2_d2zafd1__1		Fungi	Proteobacteria	Ascomycota	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; aromatic compound catabolic process [GO:0019439]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	aromatic compound catabolic process [GO:0019439]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]			acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d3mpic2_d2rehd1__1		Fungi	Proteobacteria	Ascomycota	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; aromatic compound catabolic process [GO:0019439]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	aromatic compound catabolic process [GO:0019439]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]			acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d3mpid2_d4p13b2__1		Metazoa	Proteobacteria	Chordata	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; aromatic compound catabolic process [GO:0019439]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	aromatic compound catabolic process [GO:0019439]	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]		axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]
d3mpid2_d5k3ih3__1		Metazoa	Proteobacteria	Nematoda (roundworms)	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; aromatic compound catabolic process [GO:0019439]	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]	aromatic compound catabolic process [GO:0019439]	ascaroside biosynthetic process [GO:1904070]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]		peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA oxidase activity [GO:0003997]; ATP binding [GO:0005524]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]
d3mpja2_d4p13d2__1		Metazoa	Proteobacteria	Chordata	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; aromatic compound catabolic process [GO:0019439]	axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]; carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]	aromatic compound catabolic process [GO:0019439]	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; medium-chain fatty acid catabolic process [GO:0051793]; medium-chain fatty acid metabolic process [GO:0051791]; oxidation-reduction process [GO:0055114]; regulation of lipid metabolic process [GO:0019216]		axon [GO:0030424]; mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; identical protein binding [GO:0042802]; medium-chain-acyl-CoA dehydrogenase activity [GO:0070991]
d3mpjb2_d1t9ga1__1		Metazoa	Proteobacteria	Chordata	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; aromatic compound catabolic process [GO:0019439]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	aromatic compound catabolic process [GO:0019439]	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	electron transfer activity [GO:0009055]
d3mpjd2_d3d9fd2__1		Fungi	Proteobacteria	Ascomycota	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; aromatic compound catabolic process [GO:0019439]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]	aromatic compound catabolic process [GO:0019439]	nitrogen compound metabolic process [GO:0006807]; oxidation-reduction process [GO:0055114]			acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	FAD binding [GO:0071949]; nitroalkane oxidase activity [GO:0052664]; nitroethane oxidase activity [GO:0050141]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d3mpka__d3m3fa___1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]; pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]	modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]	ATP binding [GO:0005524]; phosphorelay sensor kinase activity [GO:0000155]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3mpsb1_d3oj5e___1			Euryarchaeota	Actinobacteria	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d3mpsh1_d1fzib___1			Euryarchaeota	Proteobacteria	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]		cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]			iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3mpsi1_d4todh___1			Euryarchaeota	Proteobacteria	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3mpua2_d4anfb2__1			Proteobacteria	Tenericutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d3mpuc1_d4kwtc1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d3mpue2_d4h31b2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d3mpwb1_d4ox7b___1			Proteobacteria	Cyanobacteria	ethanolamine degradation polyhedral organelle [GO:0031471]; structural molecule activity [GO:0005198]; ethanolamine catabolic process [GO:0046336]		ethanolamine catabolic process [GO:0046336]		ethanolamine degradation polyhedral organelle [GO:0031471]		structural molecule activity [GO:0005198]	
d3mpwc__d3dn9d1__1			Proteobacteria	Cyanobacteria	ethanolamine degradation polyhedral organelle [GO:0031471]; structural molecule activity [GO:0005198]; ethanolamine catabolic process [GO:0046336]		ethanolamine catabolic process [GO:0046336]		ethanolamine degradation polyhedral organelle [GO:0031471]		structural molecule activity [GO:0005198]	
d3mpwc__d5djbg___1			Proteobacteria	Proteobacteria	ethanolamine degradation polyhedral organelle [GO:0031471]; structural molecule activity [GO:0005198]; ethanolamine catabolic process [GO:0046336]		ethanolamine catabolic process [GO:0046336]		ethanolamine degradation polyhedral organelle [GO:0031471]		structural molecule activity [GO:0005198]	
d3mpwe__d4ox7a___1			Proteobacteria	Cyanobacteria	ethanolamine degradation polyhedral organelle [GO:0031471]; structural molecule activity [GO:0005198]; ethanolamine catabolic process [GO:0046336]		ethanolamine catabolic process [GO:0046336]		ethanolamine degradation polyhedral organelle [GO:0031471]		structural molecule activity [GO:0005198]	
d3mpwg1_d3ssqa___1			Proteobacteria	Cyanobacteria	ethanolamine degradation polyhedral organelle [GO:0031471]; structural molecule activity [GO:0005198]; ethanolamine catabolic process [GO:0046336]	identical protein binding [GO:0042802]	ethanolamine catabolic process [GO:0046336]		ethanolamine degradation polyhedral organelle [GO:0031471]		structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]
d3mpwi__d3sssa1__1			Proteobacteria	Cyanobacteria	ethanolamine degradation polyhedral organelle [GO:0031471]; structural molecule activity [GO:0005198]; ethanolamine catabolic process [GO:0046336]	identical protein binding [GO:0042802]	ethanolamine catabolic process [GO:0046336]		ethanolamine degradation polyhedral organelle [GO:0031471]		structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]
d3mpwj__d2ewha1__1			Proteobacteria	Proteobacteria	ethanolamine degradation polyhedral organelle [GO:0031471]; structural molecule activity [GO:0005198]; ethanolamine catabolic process [GO:0046336]		ethanolamine catabolic process [GO:0046336]		ethanolamine degradation polyhedral organelle [GO:0031471]		structural molecule activity [GO:0005198]	
d3mpwl__d3ssrb___1			Proteobacteria	Cyanobacteria	ethanolamine degradation polyhedral organelle [GO:0031471]; structural molecule activity [GO:0005198]; ethanolamine catabolic process [GO:0046336]	identical protein binding [GO:0042802]	ethanolamine catabolic process [GO:0046336]		ethanolamine degradation polyhedral organelle [GO:0031471]		structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]
d3mpya__d4liwa1__1			Proteobacteria	Cyanobacteria	ethanolamine degradation polyhedral organelle [GO:0031471]; structural molecule activity [GO:0005198]; ethanolamine catabolic process [GO:0046336]		ethanolamine catabolic process [GO:0046336]		ethanolamine degradation polyhedral organelle [GO:0031471]		structural molecule activity [GO:0005198]	
d3mpza1_d2z3ib___1		Fungi	Actinobacteria	Ascomycota	cytidine deaminase activity [GO:0004126]; metal ion binding [GO:0046872]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]			cytidine deaminase activity [GO:0004126]; metal ion binding [GO:0046872]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d3mpzb1_d3dh1d1__1		Metazoa	Actinobacteria	Chordata	cytidine deaminase activity [GO:0004126]; metal ion binding [GO:0046872]	nucleoplasm [GO:0005654]; tRNA-specific adenosine-34 deaminase complex [GO:0052718]; tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA modification [GO:0006400]; tRNA wobble adenosine to inosine editing [GO:0002100]		tRNA modification [GO:0006400]; tRNA wobble adenosine to inosine editing [GO:0002100]		nucleoplasm [GO:0005654]; tRNA-specific adenosine-34 deaminase complex [GO:0052718]	cytidine deaminase activity [GO:0004126]; metal ion binding [GO:0046872]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]
d3mpzc1_d2z3ic___1		Fungi	Actinobacteria	Ascomycota	cytidine deaminase activity [GO:0004126]; metal ion binding [GO:0046872]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]			cytidine deaminase activity [GO:0004126]; metal ion binding [GO:0046872]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d3mq8b2_d2ogqa1__1		Metazoa		Chordata		cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]; anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]		anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]		cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]		anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]
d3mqda1_d4japd2__1			Proteobacteria	Actinobacteria	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	polyketide synthase complex [GO:0034081]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		chalcone biosynthetic process [GO:0009715]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		polyketide synthase complex [GO:0034081]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d3mqda2_d1hzpa2__1			Proteobacteria	Actinobacteria	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d3mqma1_d1jm4b1__1	Metazoa	Metazoa	Chordata	Chordata	bicellular tight junction [GO:0005923]; chromosome [GO:0005694]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone methyltransferase activity (H3-K36 specific) [GO:0046975]; histone methyltransferase activity (H3-K4 specific) [GO:0042800]; histone methyltransferase activity (H3-K9 specific) [GO:0046974]; metal ion binding [GO:0046872]; cell-cell signaling [GO:0007267]; decidualization [GO:0046697]; DNA packaging [GO:0006323]; flagellated sperm motility [GO:0030317]; histone H3-K36 dimethylation [GO:0097676]; interleukin-6 production [GO:0032635]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; single fertilization [GO:0007338]; skeletal system development [GO:0001501]; tarsal gland development [GO:1903699]; transcription by RNA polymerase II [GO:0006366]; uterine gland development [GO:1903709]; uterus morphogenesis [GO:0061038]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cell-cell signaling [GO:0007267]; decidualization [GO:0046697]; DNA packaging [GO:0006323]; flagellated sperm motility [GO:0030317]; histone H3-K36 dimethylation [GO:0097676]; interleukin-6 production [GO:0032635]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; single fertilization [GO:0007338]; skeletal system development [GO:0001501]; tarsal gland development [GO:1903699]; transcription by RNA polymerase II [GO:0006366]; uterine gland development [GO:1903709]; uterus morphogenesis [GO:0061038]	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	bicellular tight junction [GO:0005923]; chromosome [GO:0005694]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone methyltransferase activity (H3-K36 specific) [GO:0046975]; histone methyltransferase activity (H3-K4 specific) [GO:0042800]; histone methyltransferase activity (H3-K9 specific) [GO:0046974]; metal ion binding [GO:0046872]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]
d3mqwa1_d1onii___1		Metazoa		Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]; deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; L-threonine catabolic process to glycine [GO:0019518]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	organonitrogen compound catabolic process [GO:1901565]	brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; L-threonine catabolic process to glycine [GO:0019518]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]	deaminase activity [GO:0019239]	deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d3mqwc1_d1qahb___1		Metazoa		Chordata	cytosol [GO:0005829]; mitochondrion [GO:0005739]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]; deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ion binding [GO:0043167]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; transition metal ion binding [GO:0046914]; brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	organonitrogen compound catabolic process [GO:1901565]	brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; lung development [GO:0030324]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]; response to lipid [GO:0033993]; response to salt [GO:1902074]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisome [GO:0005777]	deaminase activity [GO:0019239]	deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ion binding [GO:0043167]; long-chain fatty acid binding [GO:0036041]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; transition metal ion binding [GO:0046914]
d3mqwf1_d3vcza___1				Proteobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; deaminase activity [GO:0019239]; organonitrogen compound catabolic process [GO:1901565]	metal ion binding [GO:0046872]	organonitrogen compound catabolic process [GO:1901565]		cytosol [GO:0005829]; mitochondrion [GO:0005739]		deaminase activity [GO:0019239]	metal ion binding [GO:0046872]
d3mr9b1_d2ombd1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3mrbb1_d2v44a1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3mrcb1_d3u2sb2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d3mreb1_d2p4ad___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d3mrfb1_d1rz7h1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3mrgb1_d2fjfs1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3mrjb1_d1e4xl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3mrmb1_d3ojvd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3mrmb1_d3tcll2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3mrnb1_d3ntcl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3mrqb1_d3qp3b1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d3ms8a__d5manb1__1			Firmicutes	Actinobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	sucrose phosphorylase activity [GO:0009018]; cellular carbohydrate metabolic process [GO:0044262]	xylan catabolic process [GO:0045493]	cellular carbohydrate metabolic process [GO:0044262]			endo-1,4-beta-xylanase activity [GO:0031176]	sucrose phosphorylase activity [GO:0009018]
d3msda__d4ze4b___1			Firmicutes	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	6-phospho-beta-galactosidase activity [GO:0033920]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	6-phospho-beta-galactosidase activity [GO:0033920]
d3msga__d2bs9g2__1			Firmicutes	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d3msgb__d1j11c2__1			Firmicutes	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			endo-1,4-beta-xylanase activity [GO:0031176]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3msna__d3hygb___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]		defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]
d3mt6a__d2j5sb___1			Proteobacteria	Cyanobacteria	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	catalytic activity [GO:0003824]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]		ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	catalytic activity [GO:0003824]
d3mu6b__d1srsb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	cell [GO:0005623]; cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone deacetylase binding [GO:0042826]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; serum response element binding [GO:0010736]; transcription factor binding [GO:0008134]; actin cytoskeleton organization [GO:0030036]; angiogenesis involved in wound healing [GO:0060055]; associative learning [GO:0008306]; bicellular tight junction assembly [GO:0070830]; branching involved in blood vessel morphogenesis [GO:0001569]; bronchus cartilage development [GO:0060532]; cardiac myofibril assembly [GO:0055003]; cardiac vascular smooth muscle cell differentiation [GO:0060947]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-matrix adhesion [GO:0007160]; cellular response to glucose stimulus [GO:0071333]; cellular senescence [GO:0090398]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; epithelial cell-cell adhesion [GO:0090136]; epithelial structure maintenance [GO:0010669]; erythrocyte development [GO:0048821]; eyelid development in camera-type eye [GO:0061029]; face development [GO:0060324]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula formation [GO:0060347]; hematopoietic stem cell differentiation [GO:0060218]; hippocampus development [GO:0021766]; long-term memory [GO:0007616]; long-term synaptic depression [GO:0060292]; lung morphogenesis [GO:0060425]; lung smooth muscle development [GO:0061145]; megakaryocyte development [GO:0035855]; mesoderm formation [GO:0001707]; morphogenesis of an epithelial sheet [GO:0002011]; mRNA transcription by RNA polymerase II [GO:0042789]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; neuron development [GO:0048666]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; positive regulation of axon extension [GO:0045773]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of transcription by glucose [GO:0046016]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003257]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of transcription via serum response element binding [GO:0010735]; positive thymic T cell selection [GO:0045059]; primitive streak formation [GO:0090009]; regulation of cell adhesion [GO:0030155]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of water loss via skin [GO:0033561]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to toxic substance [GO:0009636]; sarcomere organization [GO:0045214]; skin morphogenesis [GO:0043589]; stress fiber assembly [GO:0043149]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea cartilage development [GO:0060534]; transcription by RNA polymerase II [GO:0006366]; trophectodermal cell differentiation [GO:0001829]	apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	actin cytoskeleton organization [GO:0030036]; angiogenesis involved in wound healing [GO:0060055]; associative learning [GO:0008306]; bicellular tight junction assembly [GO:0070830]; branching involved in blood vessel morphogenesis [GO:0001569]; bronchus cartilage development [GO:0060532]; cardiac myofibril assembly [GO:0055003]; cardiac vascular smooth muscle cell differentiation [GO:0060947]; cell-matrix adhesion [GO:0007160]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to glucose stimulus [GO:0071333]; cellular senescence [GO:0090398]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; epithelial cell-cell adhesion [GO:0090136]; epithelial structure maintenance [GO:0010669]; erythrocyte development [GO:0048821]; eyelid development in camera-type eye [GO:0061029]; face development [GO:0060324]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula formation [GO:0060347]; hematopoietic stem cell differentiation [GO:0060218]; hippocampus development [GO:0021766]; long-term memory [GO:0007616]; long-term synaptic depression [GO:0060292]; lung morphogenesis [GO:0060425]; lung smooth muscle development [GO:0061145]; megakaryocyte development [GO:0035855]; mesoderm formation [GO:0001707]; morphogenesis of an epithelial sheet [GO:0002011]; mRNA transcription by RNA polymerase II [GO:0042789]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; neuron development [GO:0048666]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; positive regulation of axon extension [GO:0045773]; positive regulation of cell differentiation [GO:0045597]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of transcription by glucose [GO:0046016]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003257]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of transcription via serum response element binding [GO:0010735]; positive thymic T cell selection [GO:0045059]; primitive streak formation [GO:0090009]; regulation of cell adhesion [GO:0030155]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of water loss via skin [GO:0033561]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to toxic substance [GO:0009636]; sarcomere organization [GO:0045214]; skin morphogenesis [GO:0043589]; stress fiber assembly [GO:0043149]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea cartilage development [GO:0060534]; transcription by RNA polymerase II [GO:0006366]; trophectodermal cell differentiation [GO:0001829]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	chromatin DNA binding [GO:0031490]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone deacetylase binding [GO:0042826]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; serum response element binding [GO:0010736]; transcription factor binding [GO:0008134]
d3mu6c__d1tqeq___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; histone methyltransferase complex [GO:0035097]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; histone deacetylase activity [GO:0004407]; histone deacetylase activity (H4-K16 specific) [GO:0034739]; histone deacetylase binding [GO:0042826]; protein deacetylase activity [GO:0033558]; protein kinase C binding [GO:0005080]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cellular response to insulin stimulus [GO:0032869]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; histone H4-K16 deacetylation [GO:1990678]; inflammatory response [GO:0006954]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of lipoprotein lipase activity [GO:0051005]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; regulation of skeletal muscle fiber development [GO:0048742]; regulation of striated muscle cell differentiation [GO:0051153]	apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of glucose import [GO:0046326]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription by RNA polymerase II [GO:0045944]; transcription, DNA-templated [GO:0006351]; ventricular cardiac myofibril assembly [GO:0055005]	B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cellular response to insulin stimulus [GO:0032869]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; histone H4-K16 deacetylation [GO:1990678]; inflammatory response [GO:0006954]; negative regulation of cytokine secretion [GO:0050710]; negative regulation of lipoprotein lipase activity [GO:0051005]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; regulation of skeletal muscle fiber development [GO:0048742]; regulation of striated muscle cell differentiation [GO:0051153]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; histone methyltransferase complex [GO:0035097]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; sequence-specific DNA binding [GO:0043565]; SMAD binding [GO:0046332]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	histone deacetylase activity [GO:0004407]; histone deacetylase activity (H4-K16 specific) [GO:0034739]; histone deacetylase binding [GO:0042826]; protein deacetylase activity [GO:0033558]; protein kinase C binding [GO:0005080]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]
d3mu8a__d1gbta___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3muab__d1jyzo5__1			Firmicutes		endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	
d3muec1_d1mb2f___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]; pantothenate biosynthetic process from valine [GO:0033317]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	pantothenate biosynthetic process from valine [GO:0033317]	tryptophanyl-tRNA aminoacylation [GO:0006436]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d3mugc2_d4whtl1__1						viral envelope [GO:0019031]				viral envelope [GO:0019031]		
d3muge1_d1rukl2__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3mugg1_d5xhga1__1												
d3mugg2_d1a6za1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3mugg2_d2ny1c1__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3mugi1_d1lhza1__1		Metazoa		Chordata								
d3mugi1_d3p73a2__1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]		amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]		cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]		protein homodimerization activity [GO:0042803]
d3mugi2_d4w68a___1												
d3mugk2_d3ch1h___1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3muhl2_d1y0le1__1												
d3muia__d1jz3d5__1			Firmicutes	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	endo-1,4-beta-xylanase activity [GO:0031176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3muib__d2nsxd2__1		Metazoa	Firmicutes	Chordata	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	xylan catabolic process [GO:0045493]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	endo-1,4-beta-xylanase activity [GO:0031176]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d3muoa2_d3dqzd___1		Viridiplantae	Proteobacteria	Streptophyta	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	mandelonitrile lyase activity [GO:0046593]; methyl indole-3-acetate esterase activity [GO:0080030]; methyl jasmonate esterase activity [GO:0080032]; methyl salicylate esterase activity [GO:0080031]; glycoside catabolic process [GO:0016139]; jasmonic acid metabolic process [GO:0009694]; response to wounding [GO:0009611]; salicylic acid metabolic process [GO:0009696]		glycoside catabolic process [GO:0016139]; jasmonic acid metabolic process [GO:0009694]; response to wounding [GO:0009611]; salicylic acid metabolic process [GO:0009696]			serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	mandelonitrile lyase activity [GO:0046593]; methyl indole-3-acetate esterase activity [GO:0080030]; methyl jasmonate esterase activity [GO:0080032]; methyl salicylate esterase activity [GO:0080031]
d3muoa2_d5kwjb___1			Proteobacteria	Actinobacteria	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cell wall [GO:0005618]; extracellular region [GO:0005576]; diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]; glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]		glycolipid biosynthetic process [GO:0009247]; lipid transport [GO:0006869]; mycolate cell wall layer assembly [GO:0071769]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	diacylglycerol O-acyltransferase activity [GO:0004144]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; trehalose O-mycolyltransferase activity [GO:0050348]; zymogen binding [GO:0035375]
d3muy12_d1jz0a2__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3muy13_d2vvnb2__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]
d3muy21_d3k77f___1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	lactose catabolic process [GO:0005990]	base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	beta-galactosidase complex [GO:0009341]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]
d3muy33_d1bhga3__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]; carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glucuronoside catabolic process [GO:0019391]; glycosaminoglycan catabolic process [GO:0006027]; hyaluronan catabolic process [GO:0030214]; neutrophil degranulation [GO:0043312]	beta-galactosidase complex [GO:0009341]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; protein domain specific binding [GO:0019904]; signaling receptor binding [GO:0005102]
d3muy35_d1rwaa3__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; lyase activity [GO:0016829]
d3muy43_d1mfua2__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d3muz21_d2je8b4__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-mannosidase activity [GO:0004567]
d3muz22_d5c70a2__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3muz23_d2uwfa1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	endo-1,4-beta-xylanase activity [GO:0031176]
d3muz24_d2vqtb1__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-mannosidase activity [GO:0004567]
d3muz31_d3ogsa4__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase activity [GO:0004565]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-galactosidase activity [GO:0004565]
d3muz33_d2d0ga3__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d3muz34_d1f4aa1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3muz35_d1ygab___1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]	lactose catabolic process [GO:0005990]	galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d3muz42_d1ghom2__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3muz43_d1e3xa2__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d3muz43_d5i77a1__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cellulase activity [GO:0008810]
d3mv013_d2ceqb___1			Proteobacteria	Crenarchaeota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]
d3mv023_d1bgmo5__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3mv031_d2quoa___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	toxin activity [GO:0090729]
d3mv032_d2vzua4__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3mv043_d1gqia1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	lactose catabolic process [GO:0005990]	glucuronoxylan catabolic process [GO:2000886]	beta-galactosidase complex [GO:0009341]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]
d3mv115_d3t2pb5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3mv121_d4ryda2__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	lactose catabolic process [GO:0005990]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	beta-galactosidase complex [GO:0009341]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d3mv124_d4duxd2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3mv125_d3d4ya2__1		Metazoa	Proteobacteria	Arthropoda	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d3mv144_d3lpgb2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	lactose catabolic process [GO:0005990]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	beta-galactosidase complex [GO:0009341]	cytosol [GO:0005829]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d3mv145_d3czna2__1		Metazoa	Proteobacteria	Arthropoda	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d3mv6m__d3pcgc___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d3mv6o__d3pcad___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d3mv7b__d2fl5a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3mv9b1_d5nmdd2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3mvda__d3azmh___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3mvdf__d1ku5b___1	Metazoa		Chordata	Euryarchaeota	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]			nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3mvdf__d1m18d___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; DNA-templated transcription, initiation [GO:0006352]		DNA-templated transcription, initiation [GO:0006352]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3mvfa__d1s44a___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	extracellular space [GO:0005615]; pigment binding [GO:0031409]; protein-chromophore linkage [GO:0018298]	vasodilation [GO:0042311]	protein-chromophore linkage [GO:0018298]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	pigment binding [GO:0031409]
d3mvib__d4erib___1	Metazoa		Chordata	Proteobacteria	cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; in utero embryonic development [GO:0001701]; inosine biosynthetic process [GO:0046103]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]		cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]		adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]	carboxy-lyase activity [GO:0016831]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3mvqa1_d1b26d2__1				Thermotogae		glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]				glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d3mvqb1_d1bw9b2__1				Actinobacteria		nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]		L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]				nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d3mvqb2_d3aoga2__1				Deinococcus-Thermus		nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]				nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d3mvtc__d1p1ma2__1	Metazoa		Chordata	Thermotogae	cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]; adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; in utero embryonic development [GO:0001701]; inosine biosynthetic process [GO:0046103]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]	5'-methylthioadenosine deaminase activity [GO:0090614]; adenosine deaminase activity [GO:0004000]; metal ion binding [GO:0046872]; S-adenosylhomocysteine deaminase activity [GO:0050270]	adenosine catabolic process [GO:0006154]; adenosine metabolic process [GO:0046085]; aging [GO:0007568]; cell adhesion [GO:0007155]; dATP catabolic process [GO:0046061]; deoxyadenosine catabolic process [GO:0006157]; embryonic digestive tract development [GO:0048566]; germinal center B cell differentiation [GO:0002314]; histamine secretion [GO:0001821]; hypoxanthine biosynthetic process [GO:0046101]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian sleep/wake cycle, non-REM sleep [GO:0042323]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of mucus secretion [GO:0070256]; negative regulation of penile erection [GO:0060407]; negative regulation of thymocyte apoptotic process [GO:0070244]; Peyer's patch development [GO:0048541]; placenta development [GO:0001890]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of germinal center formation [GO:0002636]; positive regulation of heart rate [GO:0010460]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of T cell receptor signaling pathway [GO:0050862]; purine nucleotide salvage [GO:0032261]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of T cell differentiation [GO:0045580]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to morphine [GO:0043278]; response to vitamin E [GO:0033197]; T cell activation [GO:0042110]; trophectodermal cell differentiation [GO:0001829]; xanthine biosynthetic process [GO:0046111]		cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; lysosome [GO:0005764]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]		adenosine deaminase activity [GO:0004000]; purine nucleoside binding [GO:0001883]; zinc ion binding [GO:0008270]	5'-methylthioadenosine deaminase activity [GO:0090614]; adenosine deaminase activity [GO:0004000]; metal ion binding [GO:0046872]; S-adenosylhomocysteine deaminase activity [GO:0050270]
d3mvwa__d1lage___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	outer membrane-bounded periplasmic space [GO:0030288]; amino acid transport [GO:0006865]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	amino acid transport [GO:0006865]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]	
d3mvyb__d2m8ca___1			Proteobacteria		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]		negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]	
d3mvyb__d4oevb___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transport [GO:0055085]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]	
d3mvzb__d4q30d___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3mw4b1_d1ax1a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	GABA-ergic synapse [GO:0098982]; integral component of membrane [GO:0016021]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; calcium channel regulator activity [GO:0005246]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle exocytosis [GO:2000300]; synapse assembly [GO:0007416]	carbohydrate binding [GO:0030246]	cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle exocytosis [GO:2000300]; synapse assembly [GO:0007416]		GABA-ergic synapse [GO:0098982]; integral component of membrane [GO:0016021]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]		calcium channel regulator activity [GO:0005246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d3mw9a2_d2yfgc1__1												
d3mw9b2_d4fr5a1__1				Proteobacteria		cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d3mw9c2_d1hwyc2__1		Metazoa		Chordata		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]		mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d3mw9f1_d4ej0a___1				Proteobacteria		ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; carbohydrate metabolic process [GO:0005975]		ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; carbohydrate metabolic process [GO:0005975]				ADP-glyceromanno-heptose 6-epimerase activity [GO:0008712]; NADP binding [GO:0050661]
d3mwaa1_d3p61b___1			Apicomplexa	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3mwiu__d1vcwa2__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]	serine-type endopeptidase activity [GO:0004252]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3mwja__d2bkua___1		Fungi	Deinococcus-Thermus	Ascomycota	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	cytoplasm [GO:0005737]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; disordered domain specific binding [GO:0097718]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]; mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore complex assembly [GO:0051292]; phosphatidylcholine biosynthetic process [GO:0006656]; protein import into nucleus [GO:0006606]; protein targeting to membrane [GO:0006612]; regulation of protein desumoylation [GO:0060188]		mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore complex assembly [GO:0051292]; phosphatidylcholine biosynthetic process [GO:0006656]; protein import into nucleus [GO:0006606]; protein targeting to membrane [GO:0006612]; regulation of protein desumoylation [GO:0060188]		cytoplasm [GO:0005737]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleus [GO:0005634]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	disordered domain specific binding [GO:0097718]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]
d3mwjb__d2kbea___1		Fungi	Deinococcus-Thermus	Ascomycota	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nuclear membrane [GO:0031965]; nuclear pore cytoplasmic filaments [GO:0044614]; nucleus [GO:0005634]; polysome [GO:0005844]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-dependent ATPase activity [GO:0008186]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; translational termination [GO:0006415]; tRNA export from nucleus [GO:0006409]		mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; translational termination [GO:0006415]; tRNA export from nucleus [GO:0006409]		cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nuclear membrane [GO:0031965]; nuclear pore cytoplasmic filaments [GO:0044614]; nucleus [GO:0005634]; polysome [GO:0005844]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	ATP binding [GO:0005524]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; RNA helicase activity [GO:0003724]
d3mwla__d4klnc3__1		Metazoa	Deinococcus-Thermus	Chordata	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d3mwmb__d4mtdb___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of secondary metabolite biosynthetic process [GO:1900376]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of secondary metabolite biosynthetic process [GO:1900376]; transcription, DNA-templated [GO:0006351]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of secondary metabolite biosynthetic process [GO:1900376]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of secondary metabolite biosynthetic process [GO:1900376]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]
d3mwsa__d1rq9a___1					aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]				aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3mwsa__d4fsle___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3mwsb__d4djva___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3mwsb__d5dgua___1					aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; exoribonuclease H activity [GO:0004533]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3mx6a__d3tavb1__1			Proteobacteria	Actinobacteria	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]			metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]
d3mx6b1_d3tava1__1			Proteobacteria	Actinobacteria	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]; protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]	protein initiator methionine removal [GO:0070084]			metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]	metal ion binding [GO:0046872]; metalloaminopeptidase activity [GO:0070006]
d3mxbr__d3oola1__1		Fungi		Ascomycota		mitochondrion [GO:0005739]; endonuclease activity [GO:0004519]; intron homing [GO:0006314]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]		intron homing [GO:0006314]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]		mitochondrion [GO:0005739]		endonuclease activity [GO:0004519]
d3mxdb__d1xe6a___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3mxdb__d2mipa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3mxea__d5p1ea___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3mxga__d1c4qd___1			Proteobacteria		extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; modulation of host virulence by virus [GO:0098676]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		toxin activity [GO:0090729]
d3mxgb__d1qohj___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d3mxge__d1r4qf___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; negative regulation of translation [GO:0017148]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	negative regulation of translation [GO:0017148]	extracellular region [GO:0005576]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3mxgf__d3chbf___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]		galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d3mxgg__d1chqh___1			Proteobacteria	Proteobacteria	extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]; galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]; killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]	killing of cells of other organism [GO:0031640]; pathogenesis [GO:0009405]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]	extracellular region [GO:0005576]	catalytic complex [GO:1902494]; extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; periplasmic space [GO:0042597]		galactose binding [GO:0005534]; host cell surface binding [GO:0046812]; toxin activity [GO:0090729]
d3mxpa__d4kjna___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3mxvl1_d4rgnc1__1				Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d3mxvl2_d1fj1c2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3mxvl2_d5x8ma___1		Metazoa		Chordata		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]		cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		
d3mxwa__d1r44f___1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; laminin-1 binding [GO:0043237]; morphogen activity [GO:0016015]; patched binding [GO:0005113]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]; androgen metabolic process [GO:0008209]; animal organ formation [GO:0048645]; apoptotic signaling pathway [GO:0097190]; artery development [GO:0060840]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; blood coagulation [GO:0007596]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bud outgrowth involved in lung branching [GO:0060447]; camera-type eye development [GO:0043010]; canonical Wnt signaling pathway [GO:0060070]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell development [GO:0048468]; cell fate specification [GO:0001708]; cell-cell signaling [GO:0007267]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; cerebellar granule cell precursor proliferation [GO:0021930]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic skeletal system development [GO:0048706]; endocytosis [GO:0006897]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial-mesenchymal signaling involved in prostate gland development [GO:0060738]; establishment of cell polarity [GO:0030010]; forebrain development [GO:0030900]; formation of anatomical boundary [GO:0048859]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; inner ear development [GO:0048839]; intein-mediated protein splicing [GO:0016539]; intermediate filament organization [GO:0045109]; left lung development [GO:0060459]; limb bud formation [GO:0060174]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; lymphoid progenitor cell differentiation [GO:0002320]; male genitalia development [GO:0030539]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal smoothened signaling pathway involved in prostate gland development [GO:0060783]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephros development [GO:0001656]; midbrain development [GO:0030901]; myoblast differentiation [GO:0045445]; myotube differentiation [GO:0014902]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of kidney smooth muscle cell differentiation [GO:2000357]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of ureter smooth muscle cell differentiation [GO:2000062]; negative thymic T cell selection [GO:0045060]; neural crest cell migration [GO:0001755]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; osteoblast development [GO:0002076]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; polarity specification of anterior/posterior axis [GO:0009949]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of kidney smooth muscle cell differentiation [GO:2000358]; positive regulation of mesenchymal cell proliferation involved in ureter development [GO:2000729]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sclerotome development [GO:0061189]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ureter smooth muscle cell differentiation [GO:2000063]; positive regulation of Wnt signaling pathway [GO:0030177]; positive thymic T cell selection [GO:0045059]; primary prostatic bud elongation [GO:0060516]; prostate epithelial cord elongation [GO:0060523]; prostate gland development [GO:0030850]; protein localization to nucleus [GO:0034504]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782]; regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry [GO:1900175]; regulation of odontogenesis [GO:0042481]; regulation of prostatic bud formation [GO:0060685]; regulation of protein localization to nucleus [GO:1900180]; regulation of proteolysis [GO:0030162]; renal system development [GO:0072001]; right lung development [GO:0060458]; roof of mouth development [GO:0060021]; salivary gland cavitation [GO:0060662]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; somite development [GO:0061053]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord motor neuron differentiation [GO:0021522]; stem cell development [GO:0048864]; striated muscle tissue development [GO:0014706]; T cell differentiation in thymus [GO:0033077]; telencephalon regionalization [GO:0021978]; thalamus development [GO:0021794]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea morphogenesis [GO:0060439]; tracheoesophageal septum formation [GO:1905327]; vasculogenesis [GO:0001570]; ventral midline development [GO:0007418]	dipeptidase activity [GO:0016805]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; cell wall organization [GO:0071555]; response to antibiotic [GO:0046677]	androgen metabolic process [GO:0008209]; animal organ formation [GO:0048645]; apoptotic signaling pathway [GO:0097190]; artery development [GO:0060840]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; blood coagulation [GO:0007596]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bud outgrowth involved in lung branching [GO:0060447]; camera-type eye development [GO:0043010]; canonical Wnt signaling pathway [GO:0060070]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell-cell signaling [GO:0007267]; cell development [GO:0048468]; cell fate specification [GO:0001708]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; cerebellar granule cell precursor proliferation [GO:0021930]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic skeletal system development [GO:0048706]; endocytosis [GO:0006897]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial-mesenchymal signaling involved in prostate gland development [GO:0060738]; establishment of cell polarity [GO:0030010]; forebrain development [GO:0030900]; formation of anatomical boundary [GO:0048859]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; inner ear development [GO:0048839]; intein-mediated protein splicing [GO:0016539]; intermediate filament organization [GO:0045109]; left lung development [GO:0060459]; limb bud formation [GO:0060174]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung lobe morphogenesis [GO:0060463]; lymphoid progenitor cell differentiation [GO:0002320]; male genitalia development [GO:0030539]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal smoothened signaling pathway involved in prostate gland development [GO:0060783]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephros development [GO:0001656]; midbrain development [GO:0030901]; myoblast differentiation [GO:0045445]; myotube differentiation [GO:0014902]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of kidney smooth muscle cell differentiation [GO:2000357]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of ureter smooth muscle cell differentiation [GO:2000062]; negative thymic T cell selection [GO:0045060]; neural crest cell migration [GO:0001755]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; osteoblast development [GO:0002076]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; polarity specification of anterior/posterior axis [GO:0009949]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of kidney smooth muscle cell differentiation [GO:2000358]; positive regulation of mesenchymal cell proliferation involved in ureter development [GO:2000729]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sclerotome development [GO:0061189]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ureter smooth muscle cell differentiation [GO:2000063]; positive regulation of Wnt signaling pathway [GO:0030177]; positive thymic T cell selection [GO:0045059]; primary prostatic bud elongation [GO:0060516]; prostate epithelial cord elongation [GO:0060523]; prostate gland development [GO:0030850]; protein localization to nucleus [GO:0034504]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782]; regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry [GO:1900175]; regulation of odontogenesis [GO:0042481]; regulation of prostatic bud formation [GO:0060685]; regulation of protein localization to nucleus [GO:1900180]; regulation of proteolysis [GO:0030162]; renal system development [GO:0072001]; right lung development [GO:0060458]; roof of mouth development [GO:0060021]; salivary gland cavitation [GO:0060662]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; somite development [GO:0061053]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord motor neuron differentiation [GO:0021522]; stem cell development [GO:0048864]; striated muscle tissue development [GO:0014706]; T cell differentiation in thymus [GO:0033077]; telencephalon regionalization [GO:0021978]; thalamus development [GO:0021794]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea morphogenesis [GO:0060439]; tracheoesophageal septum formation [GO:1905327]; vasculogenesis [GO:0001570]; ventral midline development [GO:0007418]	cell wall organization [GO:0071555]; response to antibiotic [GO:0046677]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; laminin-1 binding [GO:0043237]; morphogen activity [GO:0016015]; patched binding [GO:0005113]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]	dipeptidase activity [GO:0016805]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]
d3mxwa__d3k7hb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; laminin-1 binding [GO:0043237]; morphogen activity [GO:0016015]; patched binding [GO:0005113]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]; androgen metabolic process [GO:0008209]; animal organ formation [GO:0048645]; apoptotic signaling pathway [GO:0097190]; artery development [GO:0060840]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; blood coagulation [GO:0007596]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bud outgrowth involved in lung branching [GO:0060447]; camera-type eye development [GO:0043010]; canonical Wnt signaling pathway [GO:0060070]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell development [GO:0048468]; cell fate specification [GO:0001708]; cell-cell signaling [GO:0007267]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; cerebellar granule cell precursor proliferation [GO:0021930]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic skeletal system development [GO:0048706]; endocytosis [GO:0006897]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial-mesenchymal signaling involved in prostate gland development [GO:0060738]; establishment of cell polarity [GO:0030010]; forebrain development [GO:0030900]; formation of anatomical boundary [GO:0048859]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; inner ear development [GO:0048839]; intein-mediated protein splicing [GO:0016539]; intermediate filament organization [GO:0045109]; left lung development [GO:0060459]; limb bud formation [GO:0060174]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; lymphoid progenitor cell differentiation [GO:0002320]; male genitalia development [GO:0030539]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal smoothened signaling pathway involved in prostate gland development [GO:0060783]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephros development [GO:0001656]; midbrain development [GO:0030901]; myoblast differentiation [GO:0045445]; myotube differentiation [GO:0014902]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of kidney smooth muscle cell differentiation [GO:2000357]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of ureter smooth muscle cell differentiation [GO:2000062]; negative thymic T cell selection [GO:0045060]; neural crest cell migration [GO:0001755]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; osteoblast development [GO:0002076]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; polarity specification of anterior/posterior axis [GO:0009949]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of kidney smooth muscle cell differentiation [GO:2000358]; positive regulation of mesenchymal cell proliferation involved in ureter development [GO:2000729]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sclerotome development [GO:0061189]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ureter smooth muscle cell differentiation [GO:2000063]; positive regulation of Wnt signaling pathway [GO:0030177]; positive thymic T cell selection [GO:0045059]; primary prostatic bud elongation [GO:0060516]; prostate epithelial cord elongation [GO:0060523]; prostate gland development [GO:0030850]; protein localization to nucleus [GO:0034504]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782]; regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry [GO:1900175]; regulation of odontogenesis [GO:0042481]; regulation of prostatic bud formation [GO:0060685]; regulation of protein localization to nucleus [GO:1900180]; regulation of proteolysis [GO:0030162]; renal system development [GO:0072001]; right lung development [GO:0060458]; roof of mouth development [GO:0060021]; salivary gland cavitation [GO:0060662]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; somite development [GO:0061053]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord motor neuron differentiation [GO:0021522]; stem cell development [GO:0048864]; striated muscle tissue development [GO:0014706]; T cell differentiation in thymus [GO:0033077]; telencephalon regionalization [GO:0021978]; thalamus development [GO:0021794]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea morphogenesis [GO:0060439]; tracheoesophageal septum formation [GO:1905327]; vasculogenesis [GO:0001570]; ventral midline development [GO:0007418]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; patched binding [GO:0005113]; peptidase activity [GO:0008233]; bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye photoreceptor cell fate commitment [GO:0060220]; cartilage development [GO:0051216]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; cell-cell signaling [GO:0007267]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte proliferation [GO:0035988]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint development [GO:0072498]; epithelial cell morphogenesis [GO:0003382]; epithelial cell-cell adhesion [GO:0090136]; head morphogenesis [GO:0060323]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; intein-mediated protein splicing [GO:0016539]; liver regeneration [GO:0097421]; maternal process involved in female pregnancy [GO:0060135]; multicellular organism growth [GO:0035264]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of eye pigmentation [GO:0048074]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell differentiation in thymus [GO:0033085]; neuron development [GO:0048666]; osteoblast differentiation [GO:0001649]; pancreas development [GO:0031016]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; retinal pigment epithelium development [GO:0003406]; skeletal system development [GO:0001501]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; somite development [GO:0061053]; vitelline membrane formation [GO:0030704]	androgen metabolic process [GO:0008209]; animal organ formation [GO:0048645]; apoptotic signaling pathway [GO:0097190]; artery development [GO:0060840]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; blood coagulation [GO:0007596]; branching involved in blood vessel morphogenesis [GO:0001569]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; bud outgrowth involved in lung branching [GO:0060447]; camera-type eye development [GO:0043010]; canonical Wnt signaling pathway [GO:0060070]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell-cell signaling [GO:0007267]; cell development [GO:0048468]; cell fate specification [GO:0001708]; cellular response to lithium ion [GO:0071285]; central nervous system development [GO:0007417]; cerebellar granule cell precursor proliferation [GO:0021930]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic foregut morphogenesis [GO:0048617]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic skeletal system development [GO:0048706]; endocytosis [GO:0006897]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial-mesenchymal signaling involved in prostate gland development [GO:0060738]; establishment of cell polarity [GO:0030010]; forebrain development [GO:0030900]; formation of anatomical boundary [GO:0048859]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; hindgut morphogenesis [GO:0007442]; inner ear development [GO:0048839]; intein-mediated protein splicing [GO:0016539]; intermediate filament organization [GO:0045109]; left lung development [GO:0060459]; limb bud formation [GO:0060174]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung lobe morphogenesis [GO:0060463]; lymphoid progenitor cell differentiation [GO:0002320]; male genitalia development [GO:0030539]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesenchymal smoothened signaling pathway involved in prostate gland development [GO:0060783]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephros development [GO:0001656]; midbrain development [GO:0030901]; myoblast differentiation [GO:0045445]; myotube differentiation [GO:0014902]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of kidney smooth muscle cell differentiation [GO:2000357]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of ureter smooth muscle cell differentiation [GO:2000062]; negative thymic T cell selection [GO:0045060]; neural crest cell migration [GO:0001755]; neuroblast proliferation [GO:0007405]; neuron fate commitment [GO:0048663]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; osteoblast development [GO:0002076]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; polarity specification of anterior/posterior axis [GO:0009949]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation involved in prostate gland development [GO:0060769]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of kidney smooth muscle cell differentiation [GO:2000358]; positive regulation of mesenchymal cell proliferation involved in ureter development [GO:2000729]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of sclerotome development [GO:0061189]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of striated muscle cell differentiation [GO:0051155]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ureter smooth muscle cell differentiation [GO:2000063]; positive regulation of Wnt signaling pathway [GO:0030177]; positive thymic T cell selection [GO:0045059]; primary prostatic bud elongation [GO:0060516]; prostate epithelial cord elongation [GO:0060523]; prostate gland development [GO:0030850]; protein localization to nucleus [GO:0034504]; regulation of cell population proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782]; regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry [GO:1900175]; regulation of odontogenesis [GO:0042481]; regulation of prostatic bud formation [GO:0060685]; regulation of protein localization to nucleus [GO:1900180]; regulation of proteolysis [GO:0030162]; renal system development [GO:0072001]; right lung development [GO:0060458]; roof of mouth development [GO:0060021]; salivary gland cavitation [GO:0060662]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; somite development [GO:0061053]; spinal cord dorsal/ventral patterning [GO:0021513]; spinal cord motor neuron differentiation [GO:0021522]; stem cell development [GO:0048864]; striated muscle tissue development [GO:0014706]; T cell differentiation in thymus [GO:0033077]; telencephalon regionalization [GO:0021978]; thalamus development [GO:0021794]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea morphogenesis [GO:0060439]; tracheoesophageal septum formation [GO:1905327]; vasculogenesis [GO:0001570]; ventral midline development [GO:0007418]	bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye photoreceptor cell fate commitment [GO:0060220]; cartilage development [GO:0051216]; cell-cell signaling [GO:0007267]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte proliferation [GO:0035988]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint development [GO:0072498]; epithelial cell-cell adhesion [GO:0090136]; epithelial cell morphogenesis [GO:0003382]; head morphogenesis [GO:0060323]; heart looping [GO:0001947]; intein-mediated protein splicing [GO:0016539]; in utero embryonic development [GO:0001701]; liver regeneration [GO:0097421]; maternal process involved in female pregnancy [GO:0060135]; multicellular organism growth [GO:0035264]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of eye pigmentation [GO:0048074]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell differentiation in thymus [GO:0033085]; neuron development [GO:0048666]; osteoblast differentiation [GO:0001649]; pancreas development [GO:0031016]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; retinal pigment epithelium development [GO:0003406]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; smooth muscle tissue development [GO:0048745]; somite development [GO:0061053]; vitelline membrane formation [GO:0030704]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; glycosaminoglycan binding [GO:0005539]; laminin-1 binding [GO:0043237]; morphogen activity [GO:0016015]; patched binding [GO:0005113]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; patched binding [GO:0005113]; peptidase activity [GO:0008233]
d3mxxa1_d1tbgc___1	Metazoa	Metazoa	Chordata	Chordata	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; photoreceptor disc membrane [GO:0097381]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; photoreceptor disc membrane [GO:0097381]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]	
d3my5b1_d3poma1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]; androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d3my5b2_d1jstd2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d3my5d2_d4cfwb2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d3my6a__d2qesa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3myaa__d1zv6a___1	Metazoa	Metazoa	Chordata	Chordata	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell projection membrane [GO:0031253]; cortical cytoskeleton [GO:0030863]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet dense tubular network membrane [GO:0031095]; postsynaptic density [GO:0014069]; spectrin-associated cytoskeleton [GO:0014731]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]; spectrin binding [GO:0030507]; actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; actin filament capping [GO:0051693]; actin filament reorganization [GO:0090527]; calcium-mediated signaling using extracellular calcium source [GO:0035585]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cytoskeleton organization [GO:0007010]; erythrocyte development [GO:0048821]; lamellipodium assembly [GO:0030032]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of blood coagulation [GO:0030194]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing [GO:0090303]; protein secretion by platelet [GO:0070560]; protein-containing complex assembly [GO:0065003]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; transmembrane transport [GO:0055085]	actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; actin filament capping [GO:0051693]; actin filament reorganization [GO:0090527]; calcium-mediated signaling using extracellular calcium source [GO:0035585]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cytoskeleton organization [GO:0007010]; erythrocyte development [GO:0048821]; lamellipodium assembly [GO:0030032]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of blood coagulation [GO:0030194]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing [GO:0090303]; protein-containing complex assembly [GO:0065003]; protein secretion by platelet [GO:0070560]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; transmembrane transport [GO:0055085]	actin filament bundle [GO:0032432]; cytoplasm [GO:0005737]; filopodium [GO:0030175]; filopodium tip [GO:0032433]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; ruffle [GO:0001726]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; cell projection membrane [GO:0031253]; cortical cytoskeleton [GO:0030863]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet dense tubular network membrane [GO:0031095]; postsynaptic density [GO:0014069]; spectrin-associated cytoskeleton [GO:0014731]	actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; lysophosphatidic acid binding [GO:0035727]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]; spectrin binding [GO:0030507]
d3myba__d4ryfc___1			Actinobacteria	Firmicutes	catalytic activity [GO:0003824]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	catalytic activity [GO:0003824]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d3myjb1_d1j88b2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	Fc-epsilon receptor signaling pathway [GO:0038095]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	IgE binding [GO:0019863]
d3myma__d1mlga___1	Metazoa	Metazoa	Annelida	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3mynb__d1npfa___1	Metazoa	Metazoa	Annelida	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3mytb__d5m19a1__1			Proteobacteria	Firmicutes	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; transferase activity, transferring glycosyl groups [GO:0016757]; response to antibiotic [GO:0046677]	steroid metabolic process [GO:0008202]	response to antibiotic [GO:0046677]		integral component of membrane [GO:0016021]	steroid delta-isomerase activity [GO:0004769]	penicillin binding [GO:0008658]; transferase activity, transferring glycosyl groups [GO:0016757]
d3mytd__d5wioa___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	integral component of membrane [GO:0016021]; protein secretion by the type IV secretion system [GO:0030255]	steroid metabolic process [GO:0008202]	protein secretion by the type IV secretion system [GO:0030255]		integral component of membrane [GO:0016021]	steroid delta-isomerase activity [GO:0004769]	
d3mywa__d2h6ma___1	Viridiplantae		Streptophyta		extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]		negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell mitochondrial outer membrane [GO:0044193]; host multivesicular body [GO:0072494]; icosahedral viral capsid [GO:0019030]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase inhibitor activity [GO:0004867]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3mywb__d2f9ob___1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]		defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	serine-type endopeptidase inhibitor activity [GO:0004867]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3myyb__d5iukf1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]; protein dimerization activity [GO:0046983]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		cytosol [GO:0005829]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]; protein dimerization activity [GO:0046983]
d3mz8b1_d2epfa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d3mzda2_d3it9d2__1			Proteobacteria	Proteobacteria	integral component of plasma membrane [GO:0005887]; beta-lactamase activity [GO:0008800]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall macromolecule metabolic process [GO:0044036]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan metabolic process [GO:0000270]; regulation of cell shape [GO:0008360]	integral component of plasma membrane [GO:0005887]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to drug [GO:0042493]	cell wall macromolecule metabolic process [GO:0044036]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan metabolic process [GO:0000270]; regulation of cell shape [GO:0008360]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to drug [GO:0042493]	integral component of plasma membrane [GO:0005887]	integral component of plasma membrane [GO:0005887]	beta-lactamase activity [GO:0008800]; carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]	carboxypeptidase activity [GO:0004180]; endopeptidase activity [GO:0004175]; penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]
d3mzgb1_d2kz1b2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; endosome lumen [GO:0031904]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; metal ion binding [GO:0046872]; ornithine decarboxylase activator activity [GO:0042978]; peptide hormone binding [GO:0017046]; prolactin receptor activity [GO:0004925]; protein homodimerization activity [GO:0042803]; activation of Janus kinase activity [GO:0042976]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; cell surface receptor signaling pathway [GO:0007166]; embryo implantation [GO:0007566]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cold-induced thermogenesis [GO:0120162]; steroid biosynthetic process [GO:0006694]; T cell activation [GO:0042110]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	activation of Janus kinase activity [GO:0042976]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; cell surface receptor signaling pathway [GO:0007166]; embryo implantation [GO:0007566]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cold-induced thermogenesis [GO:0120162]; steroid biosynthetic process [GO:0006694]; T cell activation [GO:0042110]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; response to interferon-alpha [GO:0035455]; response to interferon-beta [GO:0035456]; response to virus [GO:0009615]; type I interferon signaling pathway [GO:0060337]	cell surface [GO:0009986]; endosome lumen [GO:0031904]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; metal ion binding [GO:0046872]; ornithine decarboxylase activator activity [GO:0042978]; peptide hormone binding [GO:0017046]; prolactin receptor activity [GO:0004925]; protein homodimerization activity [GO:0042803]	cytokine receptor activity [GO:0004896]; protein kinase binding [GO:0019901]; type I interferon binding [GO:0019962]; type I interferon receptor activity [GO:0004905]
d3mzgb1_d5kbnd___1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; endosome lumen [GO:0031904]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; metal ion binding [GO:0046872]; ornithine decarboxylase activator activity [GO:0042978]; peptide hormone binding [GO:0017046]; prolactin receptor activity [GO:0004925]; protein homodimerization activity [GO:0042803]; activation of Janus kinase activity [GO:0042976]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; cell surface receptor signaling pathway [GO:0007166]; embryo implantation [GO:0007566]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cold-induced thermogenesis [GO:0120162]; steroid biosynthetic process [GO:0006694]; T cell activation [GO:0042110]	integral component of plasma membrane [GO:0005887]; inorganic anion transmembrane transporter activity [GO:0015103]	activation of Janus kinase activity [GO:0042976]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; cell surface receptor signaling pathway [GO:0007166]; embryo implantation [GO:0007566]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cold-induced thermogenesis [GO:0120162]; steroid biosynthetic process [GO:0006694]; T cell activation [GO:0042110]		cell surface [GO:0009986]; endosome lumen [GO:0031904]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	integral component of plasma membrane [GO:0005887]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; metal ion binding [GO:0046872]; ornithine decarboxylase activator activity [GO:0042978]; peptide hormone binding [GO:0017046]; prolactin receptor activity [GO:0004925]; protein homodimerization activity [GO:0042803]	inorganic anion transmembrane transporter activity [GO:0015103]
d3mzib__d1w2ia___1			Cyanobacteria	Euryarchaeota	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]
d3mzic__d1yrxc2__1			Cyanobacteria	Proteobacteria	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]
d3mzif__d1x0ph___1			Cyanobacteria	Cyanobacteria	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]					blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]; identical protein binding [GO:0042802]	blue light photoreceptor activity [GO:0009882]; FAD binding [GO:0071949]
d3mzna1_d1ec9d2__1			Proteobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]		D-glucarate catabolic process [GO:0042838]			glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3mzna2_d4g8tc2__1			Proteobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; glucarate catabolic process [GO:0019394]		glucarate catabolic process [GO:0019394]			glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3mznb2_d4e6mf2__1			Proteobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3mzra__d4ahdb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]
d3mzsb__d4jwua___1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; cholesterol monooxygenase (side-chain-cleaving) activity [GO:0008386]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to peptide hormone stimulus [GO:0071375]; cholesterol metabolic process [GO:0008203]; cortisol metabolic process [GO:0034650]; glucocorticoid biosynthetic process [GO:0006704]; vitamin D metabolic process [GO:0042359]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to peptide hormone stimulus [GO:0071375]; cholesterol metabolic process [GO:0008203]; cortisol metabolic process [GO:0034650]; glucocorticoid biosynthetic process [GO:0006704]; vitamin D metabolic process [GO:0042359]	(+)-camphor catabolic process [GO:0019383]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	cholesterol monooxygenase (side-chain-cleaving) activity [GO:0008386]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3mzta__d4wfhd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]; identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]; cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]
d3mztb__d3kprg___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3mztc__d1yymr2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d3mztd__d2kqnb___1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3mzte__d1yegl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3mztf__d2xkna1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3n08b1_d1wkpa___1		Viridiplantae	Chlamydiae	Streptophyta		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; phosphatidylethanolamine binding [GO:0008429]; cell differentiation [GO:0030154]; flower development [GO:0009908]; meristem determinacy [GO:0010022]; photoperiodism, flowering [GO:0048573]; positive regulation of flower development [GO:0009911]; regulation of flower development [GO:0009909]; regulation of stomatal movement [GO:0010119]		cell differentiation [GO:0030154]; flower development [GO:0009908]; meristem determinacy [GO:0010022]; photoperiodism, flowering [GO:0048573]; positive regulation of flower development [GO:0009911]; regulation of flower development [GO:0009909]; regulation of stomatal movement [GO:0010119]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]		phosphatidylethanolamine binding [GO:0008429]
d3n08b1_d2iqxa___1		Metazoa	Chlamydiae	Chordata		apical part of cell [GO:0045177]; axon terminus [GO:0043679]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; rough endoplasmic reticulum [GO:0005791]; synaptic vesicle [GO:0008021]; ATP binding [GO:0005524]; kinase binding [GO:0019900]; lipid binding [GO:0008289]; mitogen-activated protein kinase binding [GO:0051019]; protein kinase binding [GO:0019901]; receptor serine/threonine kinase binding [GO:0033612]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor binding [GO:0005102]; aging [GO:0007568]; eating behavior [GO:0042755]; hippocampus development [GO:0021766]; MAPK cascade [GO:0000165]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of acetylcholine metabolic process [GO:0060409]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of neurotransmitter levels [GO:0001505]; regulation of the force of heart contraction [GO:0002026]; response to activity [GO:0014823]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to electrical stimulus [GO:0051602]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; response to wounding [GO:0009611]; sperm capacitation [GO:0048240]; spermatid development [GO:0007286]		aging [GO:0007568]; eating behavior [GO:0042755]; hippocampus development [GO:0021766]; MAPK cascade [GO:0000165]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of acetylcholine metabolic process [GO:0060409]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of neurotransmitter levels [GO:0001505]; regulation of the force of heart contraction [GO:0002026]; response to activity [GO:0014823]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to electrical stimulus [GO:0051602]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; response to wounding [GO:0009611]; spermatid development [GO:0007286]; sperm capacitation [GO:0048240]		apical part of cell [GO:0045177]; axon terminus [GO:0043679]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; rough endoplasmic reticulum [GO:0005791]; synaptic vesicle [GO:0008021]		ATP binding [GO:0005524]; kinase binding [GO:0019900]; lipid binding [GO:0008289]; mitogen-activated protein kinase binding [GO:0051019]; protein kinase binding [GO:0019901]; receptor serine/threonine kinase binding [GO:0033612]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor binding [GO:0005102]
d3n0ea1_d4d6va1__1	Metazoa	Fungi	Chordata	Basidiomycota	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]		histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]		Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]		histone binding [GO:0042393]; methylated histone binding [GO:0035064]	
d3n0gb2_d3lgka___1	Viridiplantae		Streptophyta	Actinobacteria	chloroplast [GO:0009507]; isoprene synthase activity [GO:0034009]; magnesium ion binding [GO:0000287]	epi-isozizaene synthase activity [GO:0052680]; metal ion binding [GO:0046872]			chloroplast [GO:0009507]		isoprene synthase activity [GO:0034009]; magnesium ion binding [GO:0000287]	epi-isozizaene synthase activity [GO:0052680]; metal ion binding [GO:0046872]
d3n0ha__d3dl5c1__1	Metazoa		Chordata		cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	
d3n0ic__d3u6xn2__1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]	metal ion binding [GO:0046872]	
d3n0pa__d2gmfb1__1	Metazoa	Metazoa	Chordata	Chordata	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]	hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]	cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]
d3n0pb2_d1pvha2__1	Metazoa	Metazoa	Chordata	Chordata	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]	ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]
d3n0yb__d2eena___1			Proteobacteria	Euryarchaeota	adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]						adenylate cyclase activity [GO:0004016]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	
d3n1cc__d4c5jb1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphofructokinase activity [GO:0008443]; tagatose-6-phosphate kinase activity [GO:0009024]; cellular response to DNA damage stimulus [GO:0006974]; glycolytic process [GO:0006096]	ATP binding [GO:0005524]; phosphomethylpyrimidine kinase activity [GO:0008972]; thiamine biosynthetic process [GO:0009228]	cellular response to DNA damage stimulus [GO:0006974]; glycolytic process [GO:0006096]	thiamine biosynthetic process [GO:0009228]	cytosol [GO:0005829]		6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphofructokinase activity [GO:0008443]; tagatose-6-phosphate kinase activity [GO:0009024]	ATP binding [GO:0005524]; phosphomethylpyrimidine kinase activity [GO:0008972]
d3n1fa__d1r44a___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; patched binding [GO:0005113]; peptidase activity [GO:0008233]; bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye photoreceptor cell fate commitment [GO:0060220]; cartilage development [GO:0051216]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; cell-cell signaling [GO:0007267]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte proliferation [GO:0035988]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint development [GO:0072498]; epithelial cell morphogenesis [GO:0003382]; epithelial cell-cell adhesion [GO:0090136]; head morphogenesis [GO:0060323]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; intein-mediated protein splicing [GO:0016539]; liver regeneration [GO:0097421]; maternal process involved in female pregnancy [GO:0060135]; multicellular organism growth [GO:0035264]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of eye pigmentation [GO:0048074]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell differentiation in thymus [GO:0033085]; neuron development [GO:0048666]; osteoblast differentiation [GO:0001649]; pancreas development [GO:0031016]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; retinal pigment epithelium development [GO:0003406]; skeletal system development [GO:0001501]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; somite development [GO:0061053]; vitelline membrane formation [GO:0030704]	dipeptidase activity [GO:0016805]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; cell wall organization [GO:0071555]; response to antibiotic [GO:0046677]	bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye photoreceptor cell fate commitment [GO:0060220]; cartilage development [GO:0051216]; cell-cell signaling [GO:0007267]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte proliferation [GO:0035988]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint development [GO:0072498]; epithelial cell-cell adhesion [GO:0090136]; epithelial cell morphogenesis [GO:0003382]; head morphogenesis [GO:0060323]; heart looping [GO:0001947]; intein-mediated protein splicing [GO:0016539]; in utero embryonic development [GO:0001701]; liver regeneration [GO:0097421]; maternal process involved in female pregnancy [GO:0060135]; multicellular organism growth [GO:0035264]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of eye pigmentation [GO:0048074]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell differentiation in thymus [GO:0033085]; neuron development [GO:0048666]; osteoblast differentiation [GO:0001649]; pancreas development [GO:0031016]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; retinal pigment epithelium development [GO:0003406]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; smooth muscle tissue development [GO:0048745]; somite development [GO:0061053]; vitelline membrane formation [GO:0030704]	cell wall organization [GO:0071555]; response to antibiotic [GO:0046677]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; patched binding [GO:0005113]; peptidase activity [GO:0008233]	dipeptidase activity [GO:0016805]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]
d3n1fd1_d1qr4a2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; patched binding [GO:0005113]; peptidase activity [GO:0008233]; bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye photoreceptor cell fate commitment [GO:0060220]; cartilage development [GO:0051216]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; cell-cell signaling [GO:0007267]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte proliferation [GO:0035988]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint development [GO:0072498]; epithelial cell morphogenesis [GO:0003382]; epithelial cell-cell adhesion [GO:0090136]; head morphogenesis [GO:0060323]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; intein-mediated protein splicing [GO:0016539]; liver regeneration [GO:0097421]; maternal process involved in female pregnancy [GO:0060135]; multicellular organism growth [GO:0035264]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of eye pigmentation [GO:0048074]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell differentiation in thymus [GO:0033085]; neuron development [GO:0048666]; osteoblast differentiation [GO:0001649]; pancreas development [GO:0031016]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; retinal pigment epithelium development [GO:0003406]; skeletal system development [GO:0001501]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; somite development [GO:0061053]; vitelline membrane formation [GO:0030704]	extracellular region [GO:0005576]; cell adhesion [GO:0007155]	bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye photoreceptor cell fate commitment [GO:0060220]; cartilage development [GO:0051216]; cell-cell signaling [GO:0007267]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte proliferation [GO:0035988]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint development [GO:0072498]; epithelial cell-cell adhesion [GO:0090136]; epithelial cell morphogenesis [GO:0003382]; head morphogenesis [GO:0060323]; heart looping [GO:0001947]; intein-mediated protein splicing [GO:0016539]; in utero embryonic development [GO:0001701]; liver regeneration [GO:0097421]; maternal process involved in female pregnancy [GO:0060135]; multicellular organism growth [GO:0035264]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of eye pigmentation [GO:0048074]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell differentiation in thymus [GO:0033085]; neuron development [GO:0048666]; osteoblast differentiation [GO:0001649]; pancreas development [GO:0031016]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; retinal pigment epithelium development [GO:0003406]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]; smooth muscle tissue development [GO:0048745]; somite development [GO:0061053]; vitelline membrane formation [GO:0030704]	cell adhesion [GO:0007155]	extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; patched binding [GO:0005113]; peptidase activity [GO:0008233]	
d3n1gc__d3t04d1__1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; smoothened signaling pathway [GO:0007224]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; smoothened signaling pathway [GO:0007224]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	axonal growth cone [GO:0044295]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]		actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]
d3n1mc__d2dmka1__1	Metazoa	Metazoa	Chordata	Chordata	axonal growth cone [GO:0044295]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; smoothened signaling pathway [GO:0007224]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; phosphoprotein binding [GO:0051219]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]; innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein localization to microtubule [GO:0035372]; protein ubiquitination [GO:0016567]	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; smoothened signaling pathway [GO:0007224]	innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein localization to microtubule [GO:0035372]; protein ubiquitination [GO:0016567]	axonal growth cone [GO:0044295]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]		identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; phosphoprotein binding [GO:0051219]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; transferase activity [GO:0016740]; zinc ion binding [GO:0008270]
d3n1pb__d2vo9b2__1	Metazoa		Chordata		axonal growth cone [GO:0044295]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; smoothened signaling pathway [GO:0007224]	extracellular region [GO:0005576]; peptidase activity [GO:0008233]; cell wall organization [GO:0071555]	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; smoothened signaling pathway [GO:0007224]	cell wall organization [GO:0071555]	axonal growth cone [GO:0044295]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]		peptidase activity [GO:0008233]
d3n1sa__d1st0b1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]; D-alanine catabolic process [GO:0055130]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]; cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	D-alanine catabolic process [GO:0055130]	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]	exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]
d3n1se__d3bl7a1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]; D-alanine catabolic process [GO:0055130]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]; cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	D-alanine catabolic process [GO:0055130]	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]	adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]	exoribonuclease activity [GO:0004532]; m7G(5')pppN diphosphatase activity [GO:0050072]; RNA 7-methylguanosine cap binding [GO:0000340]
d3n1sf__d1guqb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]; D-alanine catabolic process [GO:0055130]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; galactose catabolic process via UDP-galactose [GO:0033499]	D-alanine catabolic process [GO:0055130]	galactose catabolic process via UDP-galactose [GO:0033499]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]	ferrous iron binding [GO:0008198]; galactokinase activity [GO:0004335]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]
d3n1sf__d3p0ta1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]; D-alanine catabolic process [GO:0055130]	catalytic activity [GO:0003824]	D-alanine catabolic process [GO:0055130]		cytosol [GO:0005829]		adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]	catalytic activity [GO:0003824]
d3n1sj__d1kpba___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]; D-alanine catabolic process [GO:0055130]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	D-alanine catabolic process [GO:0055130]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytosol [GO:0005829]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d3n1sm__d5in3b2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]; D-alanine catabolic process [GO:0055130]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; UDP-glucose catabolic process [GO:0006258]; UDP-glucose metabolic process [GO:0006011]	D-alanine catabolic process [GO:0055130]	galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; UDP-glucose catabolic process [GO:0006258]; UDP-glucose metabolic process [GO:0006011]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]	adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]	UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]
d3n1sn__d2q4hb2__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]; D-alanine catabolic process [GO:0055130]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	D-alanine catabolic process [GO:0055130]	carbohydrate metabolic process [GO:0005975]; galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006]; positive regulation of cellular response to phosphate starvation [GO:0080040]	cytosol [GO:0005829]		adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]	ADP binding [GO:0043531]; nucleotidyltransferase activity [GO:0016779]; ribose-5-phosphate adenylyltransferase activity [GO:0047345]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]
d3n1tb__d5klza___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]; D-alanine catabolic process [GO:0055130]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	D-alanine catabolic process [GO:0055130]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytosol [GO:0005829]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	adenosine 5'-monophosphoramidase activity [GO:0043530]; nucleotide binding [GO:0000166]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d3n1xa__d1qghi___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3n1ya__d5c6fj1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d3n1zb__d3hx5l___1			Proteobacteria		metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]		cellular aromatic compound metabolic process [GO:0006725]				metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	
d3n1zc__d3ge8g___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]	toluene catabolic process [GO:0042203]			metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d3n20a__d1xvcb___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular aromatic compound metabolic process [GO:0006725]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]			metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3n20a__d3qd8c1__1			Proteobacteria	Actinobacteria	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular aromatic compound metabolic process [GO:0006725]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3n21a__d1hyta___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3n22a__d2mbxa___1		Metazoa		Chordata		calcium ion binding [GO:0005509]						calcium ion binding [GO:0005509]
d3n22b__d1xfvs1__1		Metazoa		Chordata		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]		adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d3n26a__d2ceya___1			Chlamydiae	Proteobacteria	cell surface [GO:0009986]; extracellular region [GO:0005576]; amino acid transport [GO:0006865]	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	amino acid transport [GO:0006865]	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	cell surface [GO:0009986]; extracellular region [GO:0005576]	outer membrane-bounded periplasmic space [GO:0030288]		
d3n2da__d1ifua___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		endoplasmic reticulum [GO:0005783]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3n2je__d2ppcb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3n2jh__d2e86a2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3n2ji__d2pp9b1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3n2jj__d2xx1e1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3n2jk__d4hala2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d3n2ne1_d1t6by___1	Metazoa		Chordata	Firmicutes	cell surface [GO:0009986]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; filopodium membrane [GO:0031527]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; plasma membrane [GO:0005886]; actin filament binding [GO:0051015]; collagen binding [GO:0005518]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]; actin cytoskeleton reorganization [GO:0031532]; blood vessel development [GO:0001568]; negative regulation of extracellular matrix assembly [GO:1901202]; positive regulation of metallopeptidase activity [GO:1905050]; reproductive process [GO:0022414]; substrate adhesion-dependent cell spreading [GO:0034446]; toxin transport [GO:1901998]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process in other organism [GO:0044533]; protein homooligomerization [GO:0051260]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	actin cytoskeleton reorganization [GO:0031532]; blood vessel development [GO:0001568]; negative regulation of extracellular matrix assembly [GO:1901202]; positive regulation of metallopeptidase activity [GO:1905050]; reproductive process [GO:0022414]; substrate adhesion-dependent cell spreading [GO:0034446]; toxin transport [GO:1901998]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process in other organism [GO:0044533]; protein homooligomerization [GO:0051260]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cell surface [GO:0009986]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; filopodium membrane [GO:0031527]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	actin filament binding [GO:0051015]; collagen binding [GO:0005518]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d3n2ua__d4tlia___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3n2va__d5ldsc2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3n30b__d2kdba___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	integral component of membrane [GO:0016021]; endoplasmic reticulum unfolded protein response [GO:0030968]; spermatogenesis [GO:0007283]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	endoplasmic reticulum unfolded protein response [GO:0030968]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	integral component of membrane [GO:0016021]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	
d3n31a__d1il3a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		endoplasmic reticulum [GO:0005783]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3n34a1_d3g1db___1			Apicomplexa	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3n34a1_d3ovrb___1		Metazoa	Apicomplexa	Chordata	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3n35a__d1jxnb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3n35a__d3l2ye___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d3n36a__d1w2tb1__1	Viridiplantae		Streptophyta	Thermotogae	carbohydrate binding [GO:0030246]	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]	beta-fructofuranosidase activity [GO:0004564]
d3n39b__d3rbcd___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3n3aa__d3e1pd___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3n3ab__d3is7o___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3n3gb__d7pcka___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d3n3ha__d1vlng___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3n3ia2_d5ivqb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	aspartic-type endopeptidase activity [GO:0004190]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3n3ja__d3czvb___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; myelin sheath [GO:0043209]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; myelin sheath [GO:0043209]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3n3ka__d1nbfa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d3n3lf__d4lltb1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; isoprenoid biosynthetic process [GO:0008299]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]		dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]
d3n3vc__d5cjpc___1		Metazoa		Chordata		apical part of cell [GO:0045177]; cell [GO:0005623]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]; apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]		actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; actin filament organization [GO:0007015]; adherens junction organization [GO:0034332]; blood coagulation [GO:0007596]; cardiac conduction system development [GO:0003161]; Cdc42 protein signal transduction [GO:0032488]; cell junction assembly [GO:0034329]; cell projection assembly [GO:0030031]; cellular protein localization [GO:0034613]; cellular response to interferon-gamma [GO:0071346]; dendritic cell migration [GO:0036336]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; filopodium assembly [GO:0046847]; Golgi organization [GO:0007030]; heart contraction [GO:0060047]; integrin-mediated signaling pathway [GO:0007229]; interleukin-12-mediated signaling pathway [GO:0035722]; macrophage differentiation [GO:0030225]; modification of synaptic structure [GO:0099563]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein complex assembly [GO:0031333]; neuron fate determination [GO:0048664]; neuropilin signaling pathway [GO:0038189]; nuclear migration [GO:0007097]; organelle transport along microtubule [GO:0072384]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell growth [GO:0030307]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of pseudopodium assembly [GO:0031274]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of synapse structural plasticity [GO:0051835]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; regulation of mitotic nuclear division [GO:0007088]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of protein binding [GO:0043393]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]; submandibular salivary gland formation [GO:0060661]; substantia nigra development [GO:0021762]; T cell costimulation [GO:0031295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral RNA genome replication [GO:0039694]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]		apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; Golgi transport complex [GO:0017119]; leading edge membrane [GO:0031256]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; secretory granule [GO:0030141]; spindle midzone [GO:0051233]; storage vacuole [GO:0000322]		apolipoprotein A-I receptor binding [GO:0034191]; GBD domain binding [GO:0032427]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; identical protein binding [GO:0042802]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; thioesterase binding [GO:0031996]; ubiquitin protein ligase activity [GO:0061630]
d3n3vd__d1sona___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; 'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]		'de novo' AMP biosynthetic process [GO:0044208]; adenosine biosynthetic process [GO:0046086]; cellular response to DNA damage stimulus [GO:0006974]; IMP metabolic process [GO:0046040]; nucleobase-containing small molecule interconversion [GO:0015949]; purine nucleotide biosynthetic process [GO:0006164]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]		adenylosuccinate synthase activity [GO:0004019]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d3n41f2_d3cnka___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	host cell cytoplasm [GO:0030430]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; virion membrane [GO:0055036]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d3n42f2_d2gixc1__1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	dendrite [GO:0030425]; dendritic spine [GO:0043197]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; intrinsic component of membrane [GO:0031224]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]; cardiac muscle cell action potential [GO:0086001]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cellular response to mechanical stimulus [GO:0071260]; magnesium ion transport [GO:0015693]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of skeletal muscle contraction via regulation of action potential [GO:0014861]; relaxation of cardiac muscle [GO:0055119]; relaxation of skeletal muscle [GO:0090076]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cardiac muscle cell action potential [GO:0086001]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cellular response to mechanical stimulus [GO:0071260]; magnesium ion transport [GO:0015693]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of skeletal muscle contraction via regulation of action potential [GO:0014861]; relaxation of cardiac muscle [GO:0055119]; relaxation of skeletal muscle [GO:0090076]	host cell cytoplasm [GO:0030430]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; virion membrane [GO:0055036]	dendrite [GO:0030425]; dendritic spine [GO:0043197]; Golgi apparatus [GO:0005794]; intercalated disc [GO:0014704]; intrinsic component of membrane [GO:0031224]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; voltage-gated potassium channel complex [GO:0008076]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]
d3n46f__d6axna___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	epi-isozizaene synthase activity [GO:0052680]; metal ion binding [GO:0046872]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]		dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	epi-isozizaene synthase activity [GO:0052680]; metal ion binding [GO:0046872]
d3n4ca__d3o0ua___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d3n4ca__d4bgfc___1	Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]	
d3n4kb1_d1vh0c1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; RNA binding [GO:0003723]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; tRNA methyltransferase activity [GO:0008175]; wobble position cytosine ribose methylation [GO:0002131]; wobble position uridine ribose methylation [GO:0002132]	cytoplasm [GO:0005737]; rRNA (pseudouridine-N3-)-methyltransferase activity [GO:0070038]	wobble position cytosine ribose methylation [GO:0002131]; wobble position uridine ribose methylation [GO:0002132]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	RNA binding [GO:0003723]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; tRNA methyltransferase activity [GO:0008175]	rRNA (pseudouridine-N3-)-methyltransferase activity [GO:0070038]
d3n4ma2_d1cgpb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3n5hf__d1rqjb___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	cytosol [GO:0005829]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]
d3n5jf__d5ik9a2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	cytoplasm [GO:0005737]; 5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	5-epi-aristolochene synthase activity [GO:0102698]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
d3n6kf__d1v4ja___1	Metazoa		Chordata	Thermotogae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	transferase activity [GO:0016740]; isoprenoid biosynthetic process [GO:0008299]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]		dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]	transferase activity [GO:0016740]
d3n7ab__d1v1jf___1			Actinobacteria	Actinobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n7ai__d2cjfd___1			Actinobacteria	Actinobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n7ak__d4zc1i___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n7am__d5x47j___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n7an__d4zc1j___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n7ar__d1gqog___1			Actinobacteria	Firmicutes	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n7au__d4zc1c___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n7hb__d1ls8a___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	pheromone binding [GO:0005550]; response to pheromone [GO:0019236]		response to pheromone [GO:0019236]			odorant binding [GO:0005549]	pheromone binding [GO:0005550]
d3n7ka2_d1fv3b2__1				Firmicutes	extracellular region [GO:0005576]; ganglioside binding [GO:0035594]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; membrane protein proteolysis [GO:0033619]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of neurotransmitter secretion [GO:0046929]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	membrane protein proteolysis [GO:0033619]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ganglioside binding [GO:0035594]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d3n7la2_d3hn1a2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]	negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]	clathrin-coated endocytic vesicle membrane [GO:0030669]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d3n81a__d4oe2c___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3n81g__d1o02a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3n82a__d1o01d___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3n82a__d5f2cd___1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3n82b__d4go2c___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]
d3n82d__d4h73a___1	Metazoa		Chordata	Crenarchaeota	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3n82e__d5klob___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3n82g__d3rjla___1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3n82h__d5abmc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	cytosol [GO:0005829]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]
d3n83b__d4qetb___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	
d3n83g__d4ywec___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	metal ion binding [GO:0046872]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	metal ion binding [GO:0046872]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3n84a__d1ad5b2__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]
d3n84c__d3ps5a1__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	alpha-beta T cell receptor complex [GO:0042105]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cell adhesion molecule binding [GO:0050839]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; abortive mitotic cell cycle [GO:0033277]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein dephosphorylation [GO:0006470]; regulation of B cell differentiation [GO:0045577]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	abortive mitotic cell cycle [GO:0033277]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; cytokine-mediated signaling pathway [GO:0019221]; G protein-coupled receptor signaling pathway [GO:0007186]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002924]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein dephosphorylation [GO:0006470]; regulation of B cell differentiation [GO:0045577]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	alpha-beta T cell receptor complex [GO:0042105]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	cell adhesion molecule binding [GO:0050839]; phosphorylation-dependent protein binding [GO:0140031]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d3n84f__d4ohia1__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]; abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]
d3n86f__d4rc9h___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n86h__d2cjfb___1			Actinobacteria	Actinobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n86q__d5x47a___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n87c__d1gu0b___1			Actinobacteria	Actinobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n87g__d1v1jd___1			Actinobacteria	Actinobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n87m__d5wrfa___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n87o__d5yhmh___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n8ka__d4zc1d___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n8kd__d2c4va___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n8kd__d5wrfb___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n8kg__d5yhmb___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n8ks__d1gu0a___1			Actinobacteria	Actinobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n8ks__d5yhmf___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n8kt__d5yhmg___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n8kw__d4rhcl___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n8ni__d2bt4j___1			Actinobacteria	Actinobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n8ns__d1gtzj___1			Actinobacteria	Actinobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d3n8xa2_d2boqa___1	Metazoa	Fungi	Chordata	Basidiomycota	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	extracellular region [GO:0005576]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]
d3n8za2_d2cl4x1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	chloroplast [GO:0009507]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3n9aa__d1ks3a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3n9ca__d4e97a1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3n9ea__d1p5cb___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3n9gl2_d1ty3l4__1												
d3n9gl2_d2itdb1__1				Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d3n9ia__d3l93a1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	tryptophanyl-tRNA aminoacylation [GO:0006436]	coenzyme A biosynthetic process [GO:0015937]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d3n9ja2_d3i6ad2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3n9jb1_d1zyea1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d3n9jb1_d6gsub2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d3n9ka__d4w8lb___1	Fungi		Ascomycota	Firmicutes	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]; cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	xylan catabolic process [GO:0045493]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]		cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d3n9yb__d4uhic___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]; cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via 24,25-dihydrolanosterol [GO:0033488]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein secretion [GO:0050709]; oxidation-reduction process [GO:0055114]; regulation of cholesterol biosynthetic process [GO:0045540]; steroid biosynthetic process [GO:0006694]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]
d3na0a__d2fr7a___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]; 4-methoxybenzoate monooxygenase (O-demethylating) activity [GO:0018690]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]	4-methoxybenzoate monooxygenase (O-demethylating) activity [GO:0018690]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3naal2_d2gt9a1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3nabl2_d2v17l2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3nacl2_d1j8hd1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3nada__d2wsja___1			Firmicutes	Firmicutes	carboxy-lyase activity [GO:0016831]	carboxy-lyase activity [GO:0016831]					carboxy-lyase activity [GO:0016831]	carboxy-lyase activity [GO:0016831]
d3naja1_d2yoka___1		Fungi		Ascomycota		extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]		cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d3nbac__d1j09a2__1			Actinobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d3nbad__d1vlha___1			Actinobacteria	Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d3nbfa__d3hu2c3__1		Metazoa	Deinococcus-Thermus	Chordata	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d3nbkc1_d1kaqd___1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]
d3nbqd__d4d8vb___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uridine phosphorylase activity [GO:0004850]; cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	purine nucleoside metabolic process [GO:0042278]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]		uridine phosphorylase activity [GO:0004850]	purine-nucleoside phosphorylase activity [GO:0004731]
d3nbqd__d4txjb___1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uridine phosphorylase activity [GO:0004850]; cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]	cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	uridine phosphorylase activity [GO:0004850]	uridine phosphorylase activity [GO:0004850]
d3nbtb__d5c9mb___1	Metazoa	Metazoa	Chordata	Chordata	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; glial cell apoptotic process [GO:0034349]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; negative regulation of hydrogen peroxide biosynthetic process [GO:0010730]; positive regulation of cellular respiration [GO:1901857]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to gravity [GO:0009629]; response to ischemia [GO:0002931]; response to oxidative stress [GO:0006979]	apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	apoptotic process [GO:0006915]; glial cell apoptotic process [GO:0034349]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; negative regulation of hydrogen peroxide biosynthetic process [GO:0010730]; positive regulation of cellular respiration [GO:1901857]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to gravity [GO:0009629]; response to ischemia [GO:0002931]; response to oxidative stress [GO:0006979]	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3nbte__d2lita___1	Metazoa	Fungi	Chordata	Ascomycota	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3nbud__d1irib___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; glucose-6-phosphate isomerase activity [GO:0004347]; identical protein binding [GO:0042802]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; cellular response to oxidative stress [GO:0034599]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	cellular response to oxidative stress [GO:0034599]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; hemostasis [GO:0007599]; humoral immune response [GO:0006959]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin secretion [GO:0051024]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]	glucose-6-phosphate isomerase activity [GO:0004347]; identical protein binding [GO:0042802]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]	cytokine activity [GO:0005125]; glucose-6-phosphate isomerase activity [GO:0004347]; growth factor activity [GO:0008083]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; ubiquitin protein ligase binding [GO:0031625]
d3nbuf__d2pocb___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; glucose-6-phosphate isomerase activity [GO:0004347]; identical protein binding [GO:0042802]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; cellular response to oxidative stress [GO:0034599]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; cell wall chitin biosynthetic process [GO:0006038]; cellular response to drug [GO:0035690]; chitin biosynthetic process [GO:0006031]; fructose 6-phosphate metabolic process [GO:0006002]; fungal-type cell wall chitin biosynthetic process [GO:0034221]; glucosamine biosynthetic process [GO:0006042]; glutamine metabolic process [GO:0006541]; hyphal growth [GO:0030448]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cellular response to oxidative stress [GO:0034599]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]	cellular response to drug [GO:0035690]; cell wall chitin biosynthetic process [GO:0006038]; chitin biosynthetic process [GO:0006031]; fructose 6-phosphate metabolic process [GO:0006002]; fungal-type cell wall chitin biosynthetic process [GO:0034221]; glucosamine biosynthetic process [GO:0006042]; glutamine metabolic process [GO:0006541]; hyphal growth [GO:0030448]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytosol [GO:0005829]		glucose-6-phosphate isomerase activity [GO:0004347]; identical protein binding [GO:0042802]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]
d3nbzc__d4bfub___1	Metazoa		Chordata	Actinobacteria	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	coenzyme A biosynthetic process [GO:0015937]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d3nbzf__d2iyva2__1	Metazoa		Chordata	Actinobacteria	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	cytosol [GO:0005829]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]
d3nccb2_d1ttfa___1	Metazoa	Metazoa	Chordata	Chordata	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; mammary gland development [GO:0030879]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lactation [GO:1903489]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; regulation of multicellular organism growth [GO:0040014]; response to nutrient levels [GO:0031667]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	hormone activity [GO:0005179]; prolactin receptor binding [GO:0005148]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]
d3ncea__d1cd9a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; endosome lumen [GO:0031904]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; metal ion binding [GO:0046872]; ornithine decarboxylase activator activity [GO:0042978]; peptide hormone binding [GO:0017046]; prolactin receptor activity [GO:0004925]; protein homodimerization activity [GO:0042803]; activation of Janus kinase activity [GO:0042976]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; cell surface receptor signaling pathway [GO:0007166]; embryo implantation [GO:0007566]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cold-induced thermogenesis [GO:0120162]; steroid biosynthetic process [GO:0006694]; T cell activation [GO:0042110]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	activation of Janus kinase activity [GO:0042976]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; cell surface receptor signaling pathway [GO:0007166]; embryo implantation [GO:0007566]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cold-induced thermogenesis [GO:0120162]; steroid biosynthetic process [GO:0006694]; T cell activation [GO:0042110]	cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	cell surface [GO:0009986]; endosome lumen [GO:0031904]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; metal ion binding [GO:0046872]; ornithine decarboxylase activator activity [GO:0042978]; peptide hormone binding [GO:0017046]; prolactin receptor activity [GO:0004925]; protein homodimerization activity [GO:0042803]	cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]
d3nceb1_d1cn4a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; endosome lumen [GO:0031904]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; metal ion binding [GO:0046872]; ornithine decarboxylase activator activity [GO:0042978]; peptide hormone binding [GO:0017046]; prolactin receptor activity [GO:0004925]; protein homodimerization activity [GO:0042803]; activation of Janus kinase activity [GO:0042976]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; cell surface receptor signaling pathway [GO:0007166]; embryo implantation [GO:0007566]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cold-induced thermogenesis [GO:0120162]; steroid biosynthetic process [GO:0006694]; T cell activation [GO:0042110]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	activation of Janus kinase activity [GO:0042976]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; cell surface receptor signaling pathway [GO:0007166]; embryo implantation [GO:0007566]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; lactation [GO:0007595]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cold-induced thermogenesis [GO:0120162]; steroid biosynthetic process [GO:0006694]; T cell activation [GO:0042110]	brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	cell surface [GO:0009986]; endosome lumen [GO:0031904]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; metal ion binding [GO:0046872]; ornithine decarboxylase activator activity [GO:0042978]; peptide hormone binding [GO:0017046]; prolactin receptor activity [GO:0004925]; protein homodimerization activity [GO:0042803]	erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]
d3ncjl1_d1j86a1__1		Metazoa		Chordata		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]		Fc-epsilon receptor signaling pathway [GO:0038095]		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		IgE binding [GO:0019863]
d3ncma1_d1ry7b2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of membrane [GO:0031225]; axon [GO:0030424]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]; aging [GO:0007568]; axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; commissural neuron axon guidance [GO:0071679]; homotypic cell-cell adhesion [GO:0034109]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of exocyst assembly [GO:0001928]; regulation of semaphorin-plexin signaling pathway [GO:2001260]; regulation of sensory perception of pain [GO:0051930]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	aging [GO:0007568]; axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; commissural neuron axon guidance [GO:0071679]; homotypic cell-cell adhesion [GO:0034109]; learning or memory [GO:0007611]; modulation of chemical synaptic transmission [GO:0050804]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell death [GO:0060548]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; regulation of exocyst assembly [GO:0001928]; regulation of semaphorin-plexin signaling pathway [GO:2001260]; regulation of sensory perception of pain [GO:0051930]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to lead ion [GO:0010288]; thalamus development [GO:0021794]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; phosphatase binding [GO:0019902]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3ncwa1_d1cwva1__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell surface [GO:0009986]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]		
d3ncwb2_d4gi0a___1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d3ncwc1_d1cwva2__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell surface [GO:0009986]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]		
d3ncwc2_d4mrea1__1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]		epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d3ncwd1_d1f00i1__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]		
d3ncwd2_d1muqe___1		Metazoa	Proteobacteria	Chordata	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]		cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3ncxa1_d1f00i2__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]		
d3nd2a__d5j6sb4__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; disordered domain specific binding [GO:0097718]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]; mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore complex assembly [GO:0051292]; phosphatidylcholine biosynthetic process [GO:0006656]; protein import into nucleus [GO:0006606]; protein targeting to membrane [GO:0006612]; regulation of protein desumoylation [GO:0060188]	cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]	mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore complex assembly [GO:0051292]; phosphatidylcholine biosynthetic process [GO:0006656]; protein import into nucleus [GO:0006606]; protein targeting to membrane [GO:0006612]; regulation of protein desumoylation [GO:0060188]	adaptive immune response [GO:0002250]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]	cytoplasm [GO:0005737]; NLS-dependent protein nuclear import complex [GO:0042564]; nuclear pore [GO:0005643]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	disordered domain specific binding [GO:0097718]; importin-alpha family protein binding [GO:0061676]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; protein-containing complex binding [GO:0044877]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]	aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; zinc ion binding [GO:0008270]
d3ndia__d5p8wb___1		Metazoa	Actinobacteria	Chordata	metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]		catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d3ndoa__d1xfbl___1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]; canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	canonical glycolysis [GO:0061621]; epithelial cell differentiation [GO:0030855]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	cytoplasm [GO:0005737]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	deoxyribose-phosphate aldolase activity [GO:0004139]	cytoskeletal protein binding [GO:0008092]; fructose-bisphosphate aldolase activity [GO:0004332]
d3ndub__d4xx3a___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d3ndud__d4njvd___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ndwa__d1wbmb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ndwb__d1hshd___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ndya__d3aofa___1			Firmicutes	Thermotogae	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	cellulose catabolic process [GO:0030245]	cellular glucan metabolic process [GO:0006073]		extracellular region [GO:0005576]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3ndyb__d5hosa___1			Firmicutes	Proteobacteria	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]			cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3ndyc__d1v3ka4__1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3ndzb__d3scvb___1		Viridiplantae	Firmicutes	Streptophyta	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d3ndzc__d4gxpa___1			Firmicutes	Thermotogae	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3ndzd__d3ij7a1__1		Metazoa	Firmicutes	Chordata	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cellulose catabolic process [GO:0030245]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cellulase activity [GO:0008810]; polysaccharide binding [GO:0030247]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3ne1a__d1ftfa___1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]; fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]	holo-[acyl-carrier-protein] synthase activity [GO:0008897]; magnesium ion binding [GO:0000287]
d3ne6a1_d2ex3k1__1					3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]
d3nelb1_d4pofb1__1			Euryarchaeota	Euryarchaeota	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; cell division [GO:0051301]; DNA replication initiation [GO:0006270]; intein-mediated protein splicing [GO:0016539]	aspartyl-tRNA aminoacylation [GO:0006422]	cell division [GO:0051301]; DNA replication initiation [GO:0006270]; intein-mediated protein splicing [GO:0016539]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]		aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d3nepx2_d4qo7d2__1		Metazoa	Bacteroidetes	Chordata	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-malate dehydrogenase activity [GO:0030060]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d3nera__d1u9me___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3nevd__d1xxxf___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; 2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]; aldonic acid catabolic process [GO:0046176]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aldonic acid catabolic process [GO:0046176]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3neyb1_d1f2u.1__1	Metazoa		Chordata	Euryarchaeota	centriolar satellite [GO:0034451]; cortical cytoskeleton [GO:0030863]; intracellular [GO:0005622]; membrane [GO:0016020]; plasma membrane [GO:0005886]; stereocilium [GO:0032420]; guanylate kinase activity [GO:0004385]; regulation of neutrophil chemotaxis [GO:0090022]; signal transduction [GO:0007165]	ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; double-strand break repair [GO:0006302]	regulation of neutrophil chemotaxis [GO:0090022]; signal transduction [GO:0007165]	double-strand break repair [GO:0006302]	centriolar satellite [GO:0034451]; cortical cytoskeleton [GO:0030863]; intracellular [GO:0005622]; membrane [GO:0016020]; plasma membrane [GO:0005886]; stereocilium [GO:0032420]		guanylate kinase activity [GO:0004385]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d3nf4b2_d1ws9a1__1			Actinobacteria	Deinococcus-Thermus	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]					acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]
d3nfpb1_d2rcjn2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]; interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]		activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]		external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]		interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]	
d3nfpb2_d3lizl2__1	Metazoa	Metazoa	Chordata	Arthropoda	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]; interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]	activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]		external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]		interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]	aspartic-type endopeptidase activity [GO:0004190]; metal ion binding [GO:0046872]
d3nfpl1_d3bytc___1	Metazoa		Chordata	Firmicutes	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]; interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]		external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d3nfrb__d4la4a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NAD binding [GO:0051287]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NADP binding [GO:0050661]; p-benzoquinone reductase (NADPH) activity [GO:0018541]; 4-nitrophenol catabolic process [GO:0046196]; aromatic compound catabolic process [GO:0019439]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	4-nitrophenol catabolic process [GO:0046196]; aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; p-benzoquinone reductase (NADPH) activity [GO:0018541]
d3nfsl1_d1cfvl___1		Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		antigen binding [GO:0003823]
d3nfua1_d1ecqd2__1			Proteobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]		D-glucarate catabolic process [GO:0042838]			glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3nfua2_d3toyd2__1			Proteobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]		cellular amino acid catabolic process [GO:0009063]			glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]
d3nfub1_d5fjtd1__1			Proteobacteria	Actinobacteria	glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]		menaquinone biosynthetic process [GO:0009234]			glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3nfub2_d3ujrb2__1		Metazoa	Proteobacteria	Chordata	glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3nfwa__d1ty9b___1			Actinobacteria	Proteobacteria	FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]	FMN binding [GO:0010181]; pyridoxamine-phosphate oxidase activity [GO:0004733]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]; pyridoxine biosynthetic process [GO:0008615]		pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]; pyridoxine biosynthetic process [GO:0008615]			FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]	FMN binding [GO:0010181]; pyridoxamine-phosphate oxidase activity [GO:0004733]
d3nfwb1_d5choe___1			Actinobacteria		FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]	FMN binding [GO:0010181]					FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]	FMN binding [GO:0010181]
d3nfwc__d5chod___1			Actinobacteria		FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]	FMN binding [GO:0010181]					FMN binding [GO:0010181]; monooxygenase activity [GO:0004497]	FMN binding [GO:0010181]
d3nfya__d3lntb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; carbohydrate metabolic process [GO:0005975]; erythrocyte development [GO:0048821]; respiratory gaseous exchange by respiratory system [GO:0007585]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity [GO:0046538]
d3nfza__d4uiba1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; aminoacylase activity [GO:0004046]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]		proteolysis [GO:0006508]	apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]	extracellular space [GO:0005615]	aminoacylase activity [GO:0004046]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d3ng1a1_d2c03a1__1			Deinococcus-Thermus	Deinococcus-Thermus	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	signal recognition particle [GO:0048500]	signal recognition particle [GO:0048500]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d3ng1a2_d4wzbg___1			Deinococcus-Thermus	Proteobacteria	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	nitrogen fixation [GO:0009399]	signal recognition particle [GO:0048500]	molybdenum-iron nitrogenase complex [GO:0016612]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d3ng3c__d1jcya___1			Actinobacteria	Aquificae	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	deoxyribose-phosphate aldolase activity [GO:0004139]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]
d3ng4d__d3hmbc___1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; cell wall organization [GO:0071555]; establishment of competence for transformation [GO:0030420]; peptidoglycan catabolic process [GO:0009253]; peptidoglycan turnover [GO:0009254]; sporulation resulting in formation of a cellular spore [GO:0030435]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cell wall organization [GO:0071555]; establishment of competence for transformation [GO:0030420]; peptidoglycan catabolic process [GO:0009253]; peptidoglycan turnover [GO:0009254]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]
d3ng6a__d1ha7i___1	Metazoa		Chordata	Cyanobacteria	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3ng6b__d2uunh___1	Metazoa		Chordata		hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3ng9h__d1al0f___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	host cell cytoplasm [GO:0030430]; viral procapsid maturation [GO:0046797]		viral procapsid maturation [GO:0046797]	viral capsid [GO:0019028]	host cell cytoplasm [GO:0030430]	structural molecule activity [GO:0005198]	
d3ng9h__d3shmt___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d3ng9j__d3tsxe___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]	
d3ngbc1_d4l29b1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ngbc2_d4kkaf2__1				Proteobacteria	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	structural molecule activity [GO:0005198]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3ngbf1_d5e2ul2__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d3ngbl1_d5k64a1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ngfa__d1diea___1			Proteobacteria	Actinobacteria	endonuclease activity [GO:0004519]; hydroxypyruvate isomerase activity [GO:0008903]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]		D-xylose metabolic process [GO:0042732]		cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; hydroxypyruvate isomerase activity [GO:0008903]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d3ngfb1_d4xkmd___1			Proteobacteria	Bacteroidetes	endonuclease activity [GO:0004519]; hydroxypyruvate isomerase activity [GO:0008903]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]		D-xylose metabolic process [GO:0042732]		cytoplasm [GO:0005737]	endonuclease activity [GO:0004519]; hydroxypyruvate isomerase activity [GO:0008903]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d3ngha1_d1mfla1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]; carnitine transport [GO:0015879]; in utero embryonic development [GO:0001701]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; protein localization to plasma membrane [GO:0072659]; regulation of anion transport [GO:0044070]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	carnitine transport [GO:0015879]; in utero embryonic development [GO:0001701]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; protein localization to plasma membrane [GO:0072659]; regulation of anion transport [GO:0044070]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]
d3ngka__d2a18b___1			Proteobacteria	Cyanobacteria								
d3ngka__d5djba___1			Proteobacteria	Proteobacteria								
d3ngla2_d1qrra___1		Viridiplantae	Euryarchaeota	Streptophyta	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	chloroplast [GO:0009507]; plasma membrane [GO:0005886]; coenzyme binding [GO:0050662]; sulfotransferase activity [GO:0008146]; UDPsulfoquinovose synthase activity [GO:0046507]; zinc ion binding [GO:0008270]; cellular response to phosphate starvation [GO:0016036]; glycolipid biosynthetic process [GO:0009247]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cellular response to phosphate starvation [GO:0016036]; glycolipid biosynthetic process [GO:0009247]		chloroplast [GO:0009507]; plasma membrane [GO:0005886]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	coenzyme binding [GO:0050662]; sulfotransferase activity [GO:0008146]; UDPsulfoquinovose synthase activity [GO:0046507]; zinc ion binding [GO:0008270]
d3ngsb__d3ztsa___1				Aquificae	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ngtc__d4o0nj___1				Apicomplexa	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]		ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3ngtc__d4uoga___1		Metazoa		Arthropoda	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]		ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3ngti__d3ztra___1				Aquificae	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ngxa2_d9ldtb1__1		Metazoa	Euryarchaeota	Chordata	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		cytoplasm [GO:0005737]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	L-lactate dehydrogenase activity [GO:0004459]
d3ngxb1_d2hk8h1__1			Euryarchaeota	Aquificae	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d3ngya__d3nh1b___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]; 3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]; 3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]	3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]	3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d3ngza__d4opja___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]; 3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]		cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]	cytoplasm [GO:0005737]	3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d3nh0b__d1s6qa1__1			Proteobacteria		cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]; 3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3nh1a__d2bdpa1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]; 3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]		3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d3nh2b__d4fk0a1__1			Proteobacteria		cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]; 3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]		3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d3nh7m2_d4ldeb1__1	Metazoa		Chordata		dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; dorsal aorta morphogenesis [GO:0035912]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	host cell cytoplasm [GO:0030430]	ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]	lysozyme activity [GO:0003796]
d3nh7n1_d2ifgb1__1	Metazoa	Metazoa	Chordata	Chordata	dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; dorsal aorta morphogenesis [GO:0035912]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]	ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]	cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]
d3nh7n1_d4nrzb1__1	Metazoa		Chordata		dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]		BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; dorsal aorta morphogenesis [GO:0035912]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]		dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]	
d3nh7o2_d4gw5c2__1	Metazoa		Chordata		dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]		BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; dorsal aorta morphogenesis [GO:0035912]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; fibrous ring of heart morphogenesis [GO:1905285]; heart formation [GO:0060914]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; odontogenesis of dentin-containing tooth [GO:0042475]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm structural organization [GO:0048352]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; transforming growth factor beta receptor signaling pathway [GO:0007179]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular trabecula myocardium morphogenesis [GO:0003222]		dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; HFE-transferrin receptor complex [GO:1990712]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; BMP receptor activity [GO:0098821]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]	
d3nheb__d2k1fa___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	condensed chromosome outer kinetochore [GO:0000940]; condensed nuclear chromosome [GO:0000794]; condensed nuclear chromosome, centromeric region [GO:0000780]; midbody [GO:0030496]; nucleolus [GO:0005730]; nucleus [GO:0005634]; protein tag [GO:0031386]; cellular protein modification process [GO:0006464]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system projection neuron axonogenesis [GO:0021952]; dendritic spine morphogenesis [GO:0060997]; dorsal appendage formation [GO:0046843]; lipid homeostasis [GO:0055088]; mitotic spindle organization [GO:0007052]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of Toll signaling pathway [GO:0045752]; protein sumoylation [GO:0016925]; pupariation [GO:0035073]; syncytial blastoderm mitotic cell cycle [GO:0035186]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein modification process [GO:0006464]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system projection neuron axonogenesis [GO:0021952]; dendritic spine morphogenesis [GO:0060997]; dorsal appendage formation [GO:0046843]; lipid homeostasis [GO:0055088]; mitotic spindle organization [GO:0007052]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of Toll signaling pathway [GO:0045752]; protein sumoylation [GO:0016925]; pupariation [GO:0035073]; syncytial blastoderm mitotic cell cycle [GO:0035186]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]	condensed chromosome outer kinetochore [GO:0000940]; condensed nuclear chromosome [GO:0000794]; condensed nuclear chromosome, centromeric region [GO:0000780]; midbody [GO:0030496]; nucleolus [GO:0005730]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]	protein tag [GO:0031386]
d3nhfa__d5ea2e___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3nhfb__d2q62d1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to metal ion [GO:0010038]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	FMN binding [GO:0010181]; FMN reductase (NADPH) activity [GO:0052873]
d3nhga1_d1lv5b1__1				Firmicutes	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d3nhkb__d5ulla___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3nhla__d2r96a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; membrane [GO:0016020]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; membrane [GO:0016020]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3nhlb__d1h69d___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3nhpb__d2r97a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; membrane [GO:0016020]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; membrane [GO:0016020]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3nhqa2_d2o9ba1__1			Proteobacteria	Deinococcus-Thermus	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3nhqa2_d4rpwa2__1			Proteobacteria		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]				ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	
d3nhqg1_d4b9oa___1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d3nhqg2_d3rfba___1			Proteobacteria	Firmicutes	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; methionine-R-sulfoxide reductase activity [GO:0070191]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			cytosol [GO:0005829]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	methionine-R-sulfoxide reductase activity [GO:0070191]
d3nhqh2_d1f5mb___1		Fungi	Proteobacteria	Ascomycota	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]; cellular response to oxidative stress [GO:0034599]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cellular response to oxidative stress [GO:0034599]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	L-methionine-(R)-S-oxide reductase activity [GO:0033745]; methionine-R-sulfoxide reductase activity [GO:0070191]
d3nhyb__d2fdxa___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3ni6a__d4bf8a1__1		Fungi	Apicomplexa	Ascomycota	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	nucleolus [GO:0005730]; nucleus [GO:0005634]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; histone peptidyl-prolyl isomerization [GO:0000412]; negative regulation of histone H3-K36 methylation [GO:0000415]; nucleosome assembly [GO:0006334]		histone peptidyl-prolyl isomerization [GO:0000412]; negative regulation of histone H3-K36 methylation [GO:0000415]; nucleosome assembly [GO:0006334]		nucleolus [GO:0005730]; nucleus [GO:0005634]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d3ni8a1_d1t27a___1		Metazoa	Apicomplexa	Chordata	ATPase activator activity [GO:0001671]; Hsp90 protein binding [GO:0051879]	cytoplasm [GO:0005737]; fatty-acyl-CoA binding [GO:0000062]; phosphatidylcholine binding [GO:0031210]; phosphatidylcholine transporter activity [GO:0008525]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol transfer activity [GO:0008526]; phospholipid binding [GO:0005543]; stearic acid binding [GO:0070540]; phospholipid transport [GO:0015914]		phospholipid transport [GO:0015914]		cytoplasm [GO:0005737]	ATPase activator activity [GO:0001671]; Hsp90 protein binding [GO:0051879]	fatty-acyl-CoA binding [GO:0000062]; phosphatidylcholine binding [GO:0031210]; phosphatidylcholine transporter activity [GO:0008525]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol transfer activity [GO:0008526]; phospholipid binding [GO:0005543]; stearic acid binding [GO:0070540]
d3nidf1_d5l2jb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3nidf2_d2feco1__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3nidl2_d1n64h1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3niff1_d5k9qt1__1	Metazoa		Chordata	Negarnaviricota	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	host cell surface receptor binding [GO:0046789]
d3nifl1_d1xr8b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3nigf1_d2cjvl___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	
d3nigf2_d4m5yl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	
d3nigl1_d3sgdl2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	
d3nigl2_d1clyl1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3nipa__d5efhd___1		Metazoa	Proteobacteria	Chordata	agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]			agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]
d3niqa__d5cevc___1			Proteobacteria	Firmicutes	agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]			agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]
d3niya1_d1v02c___1		Viridiplantae	Thermotogae	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3niyb1_d1byca___1		Viridiplantae	Thermotogae	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			endo-1,4-beta-xylanase activity [GO:0031176]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d3nj3a1_d1qoxm___1			Thermotogae	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]			endo-1,4-beta-xylanase activity [GO:0031176]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3nj3b1_d1uuqa___1			Thermotogae	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3nj3b1_d3gnoa___1		Viridiplantae	Thermotogae	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; scopolin beta-glucosidase activity [GO:0102483]
d3njsa__d3le7b___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3njva1_d1nkga3__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]	carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]
d3njva2_d1d7fb2__1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3njva3_d2vota4__1	Fungi		Ascomycota	Bacteroidetes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]	beta-mannosidase activity [GO:0004567]
d3nkka__d3p8ga___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3nkka__d5qcna___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d3nl4l1_d1f4yh1__1												
d3nlsb__d3oqkb___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d3nm2a__d5aewd___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	steroid metabolic process [GO:0008202]	aromatic compound catabolic process [GO:0019439]			steroid delta-isomerase activity [GO:0004769]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d3nm4a__d4da7a___1			Proteobacteria	Firmicutes	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	purine nucleoside metabolic process [GO:0042278]			6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]	purine-nucleoside phosphorylase activity [GO:0004731]
d3nm5b__d3o4vb___1			Proteobacteria	Proteobacteria	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	cytosol [GO:0005829]; adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]	L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]		cytosol [GO:0005829]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]	adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]
d3nm6b__d4oeha___1			Proteobacteria	Proteobacteria	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]		cytoplasm [GO:0005737]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]	metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]
d3nm9m__d2yula1__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]; chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; beta-catenin binding [GO:0008013]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; angiogenesis [GO:0001525]; cardiac cell fate determination [GO:0060913]; cardiogenic plate morphogenesis [GO:0003142]; cell differentiation [GO:0030154]; cell migration involved in gastrulation [GO:0042074]; cellular response to leukemia inhibitory factor [GO:1990830]; common bile duct development [GO:0061009]; embryonic foregut morphogenesis [GO:0048617]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; endocardial cell differentiation [GO:0060956]; endocardium formation [GO:0060214]; endoderm formation [GO:0001706]; endodermal cell fate determination [GO:0007493]; endodermal digestive tract morphogenesis [GO:0061031]; gall bladder development [GO:0061010]; heart formation [GO:0060914]; heart looping [GO:0001947]; inner cell mass cellular morphogenesis [GO:0001828]; metanephros development [GO:0001656]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; outflow tract morphogenesis [GO:0003151]; positive regulation of cell differentiation [GO:0045597]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; regulation of cardiac cell fate specification [GO:2000043]; regulation of embryonic development [GO:0045995]; regulation of stem cell division [GO:2000035]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification [GO:0060807]; regulation of transcription, DNA-templated [GO:0006355]; rostrocaudal neural tube patterning [GO:0021903]; signal transduction involved in regulation of gene expression [GO:0023019]; spermatogenesis [GO:0007283]; stem cell fate specification [GO:0048866]; ureter development [GO:0072189]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055]	chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	angiogenesis [GO:0001525]; cardiac cell fate determination [GO:0060913]; cardiogenic plate morphogenesis [GO:0003142]; cell differentiation [GO:0030154]; cell migration involved in gastrulation [GO:0042074]; cellular response to leukemia inhibitory factor [GO:1990830]; common bile duct development [GO:0061009]; embryonic foregut morphogenesis [GO:0048617]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; endocardial cell differentiation [GO:0060956]; endocardium formation [GO:0060214]; endodermal cell fate determination [GO:0007493]; endodermal digestive tract morphogenesis [GO:0061031]; endoderm formation [GO:0001706]; gall bladder development [GO:0061010]; heart formation [GO:0060914]; heart looping [GO:0001947]; inner cell mass cellular morphogenesis [GO:0001828]; metanephros development [GO:0001656]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; outflow tract morphogenesis [GO:0003151]; positive regulation of cell differentiation [GO:0045597]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; regulation of cardiac cell fate specification [GO:2000043]; regulation of embryonic development [GO:0045995]; regulation of stem cell division [GO:2000035]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification [GO:0060807]; rostrocaudal neural tube patterning [GO:0021903]; signal transduction involved in regulation of gene expression [GO:0023019]; spermatogenesis [GO:0007283]; stem cell fate specification [GO:0048866]; ureter development [GO:0072189]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	AT DNA binding [GO:0003680]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; transcription factor binding [GO:0008134]	beta-catenin binding [GO:0008013]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3nmib__d1m6ta___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3nmib__d2j8wb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3nmjc__d1a7va___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3nmjc__d5xzja___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3nmjd__d1cgna___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3nmkc__d4cipa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3nmma__d4l1ec___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3nmmd__d6bmgb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3nn8a1_d3upcf___1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3nn8c1_d5a3id1__1				Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d3nn9a__d4gzwd___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3nnna__d3h1ga___1			Thermotogae	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]		archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]	DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	metal ion binding [GO:0046872]
d3nnoa__d2y2cc___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]
d3nntb1_d3i7ra___1			Proteobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytosol [GO:0005829]	3-dehydroquinate dehydratase activity [GO:0003855]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; identical protein binding [GO:0042802]
d3nobb__d1wspc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	beta-catenin destruction complex [GO:0030877]; cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein homooligomerization [GO:0051260]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein homooligomerization [GO:0051260]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]	beta-catenin destruction complex [GO:0030877]; cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]	armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]
d3nobh1_d1a5ra1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d3nobh1_d1wxma1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; cellular protein modification process [GO:0006464]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of TOR signaling [GO:0032006]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular protein modification process [GO:0006464]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of TOR signaling [GO:0032006]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d3nofa__d4xcsa1__1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; RNA binding [GO:0003723]; thioredoxin peroxidase activity [GO:0008379]; cell population proliferation [GO:0008283]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; erythrocyte homeostasis [GO:0034101]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of stress-activated MAPK cascade [GO:0032872]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]; retina homeostasis [GO:0001895]; skeletal system development [GO:0001501]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell population proliferation [GO:0008283]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; erythrocyte homeostasis [GO:0034101]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of stress-activated MAPK cascade [GO:0032872]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]; retina homeostasis [GO:0001895]; skeletal system development [GO:0001501]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]	protein disulfide oxidoreductase activity [GO:0015035]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; RNA binding [GO:0003723]; thioredoxin peroxidase activity [GO:0008379]
d3nofb__d3tjkd___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	protein disulfide oxidoreductase activity [GO:0015035]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d3nopc1_d1ll8a1__1		Metazoa	Proteobacteria	Chordata	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091]; protein serine/threonine kinase activity [GO:0004674]; energy homeostasis [GO:0097009]; intracellular signal transduction [GO:0035556]; negative regulation of glycogen biosynthetic process [GO:0045719]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	energy homeostasis [GO:0097009]; intracellular signal transduction [GO:0035556]; negative regulation of glycogen biosynthetic process [GO:0045719]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	ATP binding [GO:0005524]; phosphatidylinositol binding [GO:0035091]; protein serine/threonine kinase activity [GO:0004674]
d3notc1_d1xj6b___1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]		integral component of plasma membrane [GO:0005887]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d3nouc1_d5a8bc1__1			Proteobacteria	Bacillariophyta (diatoms)	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nucleotide binding [GO:0000166]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]				ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	nucleotide binding [GO:0000166]
d3np3a__d1nibc1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3npca__d1uv5a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; JUN kinase activity [GO:0004705]; MAP kinase activity [GO:0004707]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; transcription factor binding [GO:0008134]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription factor catabolic process [GO:1901485]; protein localization to tricellular tight junction [GO:0061833]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of gene expression [GO:0010468]; rhythmic process [GO:0048511]	axon [GO:0030424]; beta-catenin destruction complex [GO:0030877]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Wnt signalosome [GO:1990909]; ATP binding [GO:0005524]; beta-catenin binding [GO:0008013]; dynactin binding [GO:0034452]; kinase activity [GO:0016301]; NF-kappaB binding [GO:0051059]; p53 binding [GO:0002039]; protease binding [GO:0002020]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II transcription factor binding [GO:0001085]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; ubiquitin protein ligase binding [GO:0031625]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular response to amyloid-beta [GO:1904646]; cellular response to interleukin-3 [GO:0036016]; circadian rhythm [GO:0007623]; dopamine receptor signaling pathway [GO:0007212]; epithelial to mesenchymal transition [GO:0001837]; ER overload response [GO:0006983]; establishment of cell polarity [GO:0030010]; excitatory postsynaptic potential [GO:0060079]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glycogen metabolic process [GO:0005977]; hippocampus development [GO:0021766]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of dendrite development [GO:2000171]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of neuron death [GO:1901215]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of type B pancreatic cell development [GO:2000077]; neuron projection development [GO:0031175]; neuron projection organization [GO:0106027]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of autophagy [GO:0010508]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of neuron death [GO:1901216]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein localization to centrosome [GO:1904781]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon extension [GO:0030516]; regulation of axonogenesis [GO:0050770]; regulation of cellular response to heat [GO:1900034]; regulation of circadian rhythm [GO:0042752]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of microtubule anchoring at centrosome [GO:0150101]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of microtubule-based process [GO:0032886]; regulation of synaptic vesicle exocytosis [GO:2000300]; signal transduction [GO:0007165]; superior temporal gyrus development [GO:0071109]; Wnt signaling pathway [GO:0016055]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; Fc-epsilon receptor signaling pathway [GO:0038095]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription factor catabolic process [GO:1901485]; protein localization to tricellular tight junction [GO:0061833]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of gene expression [GO:0010468]; rhythmic process [GO:0048511]	beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular response to amyloid-beta [GO:1904646]; cellular response to interleukin-3 [GO:0036016]; circadian rhythm [GO:0007623]; dopamine receptor signaling pathway [GO:0007212]; epithelial to mesenchymal transition [GO:0001837]; ER overload response [GO:0006983]; establishment of cell polarity [GO:0030010]; excitatory postsynaptic potential [GO:0060079]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glycogen metabolic process [GO:0005977]; hippocampus development [GO:0021766]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of dendrite development [GO:2000171]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of neuron death [GO:1901215]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of type B pancreatic cell development [GO:2000077]; neuron projection development [GO:0031175]; neuron projection organization [GO:0106027]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of autophagy [GO:0010508]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of neuron death [GO:1901216]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein localization to centrosome [GO:1904781]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon extension [GO:0030516]; regulation of axonogenesis [GO:0050770]; regulation of cellular response to heat [GO:1900034]; regulation of circadian rhythm [GO:0042752]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of microtubule anchoring at centrosome [GO:0150101]; regulation of microtubule-based process [GO:0032886]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of synaptic vesicle exocytosis [GO:2000300]; signal transduction [GO:0007165]; superior temporal gyrus development [GO:0071109]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	axon [GO:0030424]; beta-catenin destruction complex [GO:0030877]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Wnt signalosome [GO:1990909]	ATP binding [GO:0005524]; JUN kinase activity [GO:0004705]; MAP kinase activity [GO:0004707]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; beta-catenin binding [GO:0008013]; dynactin binding [GO:0034452]; kinase activity [GO:0016301]; NF-kappaB binding [GO:0051059]; p53 binding [GO:0002039]; protease binding [GO:0002020]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II transcription factor binding [GO:0001085]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; ubiquitin protein ligase binding [GO:0031625]
d3npla__d3zk5a___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]		macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]		aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3npma1_d2fg6c1__1			Proteobacteria	Bacteroidetes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]
d3npma1_d2w37b2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine catabolic process to ornithine [GO:0019547]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]
d3nq5a__d2zwfa1__1			Firmicutes	Actinobacteria	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d3nq5a__d3npyb___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d3nq6a__d3ct7b___1			Euryarchaeota	Proteobacteria	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		cytosol [GO:0005829]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3nq7a__d3thqb___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3nq7b__d4fiqd___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; pyridoxal phosphate biosynthetic process [GO:0042823]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal phosphate biosynthetic process [GO:0042823]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3nqab__d5lnsa___1		Viridiplantae	Euryarchaeota	Streptophyta	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]; amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]		cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3nqca__d2w79a___1			Euryarchaeota	Thermotogae	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]; histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]
d3nqda__d5ac7b___1			Euryarchaeota	Proteobacteria	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]; histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	histidine biosynthetic process [GO:0000105]; tryptophan biosynthetic process [GO:0000162]		cytoplasm [GO:0005737]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [GO:0003949]
d3nqea__d4utwc1__1			Euryarchaeota	Firmicutes	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	N-acylglucosamine-6-phosphate 2-epimerase activity [GO:0047465]; N-acylmannosamine-6-phosphate 2-epimerase activity [GO:0009385]; carbohydrate metabolic process [GO:0005975]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	N-acylglucosamine-6-phosphate 2-epimerase activity [GO:0047465]; N-acylmannosamine-6-phosphate 2-epimerase activity [GO:0009385]
d3nqfb__d3g1fh___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3nqjb__d3lelk___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3nqma__d4nuwa___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3nqmb__d2flij___1			Euryarchaeota	Firmicutes	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3nrjb__d2r8zk___1			Proteobacteria	Proteobacteria	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]	lipopolysaccharide biosynthetic process [GO:0009103]			3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d3nrjc1_d3umgh___1			Proteobacteria	Actinobacteria	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	(S)-2-haloacid dehalogenase activity [GO:0018784]	lipopolysaccharide biosynthetic process [GO:0009103]				3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	(S)-2-haloacid dehalogenase activity [GO:0018784]
d3nrjd1_d1zd5a1__1		Metazoa	Proteobacteria	Chordata	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipopolysaccharide biosynthetic process [GO:0009103]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3nrjg1_d5akya1__1		Metazoa	Proteobacteria	Chordata	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipopolysaccharide biosynthetic process [GO:0009103]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3nrjl__d4y2ra1__1		Metazoa	Proteobacteria	Chordata	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipopolysaccharide biosynthetic process [GO:0009103]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3nrpc1_d3pjla___1				Spirochaetes		plasma membrane [GO:0005886]				plasma membrane [GO:0005886]		
d3nrpd1_d3pjnb___1				Spirochaetes		plasma membrane [GO:0005886]				plasma membrane [GO:0005886]		
d3nrqa__d5i0xb1__1				Proteobacteria								
d3nrqb__d2o6fa___1				Spirochaetes		plasma membrane [GO:0005886]				plasma membrane [GO:0005886]		
d3nrra2_d4iqqa___1		Metazoa	Apicomplexa	Nematoda (roundworms)	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]			dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	thymidylate synthase activity [GO:0004799]
d3nrrb1_d5ecxa___1			Apicomplexa	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d3nrza1_d1l6ua___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	xanthine catabolic process [GO:0009115]	cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]
d3nrzb2_d1vdvb4__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d3nrzj1_d3av8b___1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3nrzj1_d3sfeb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	xanthine catabolic process [GO:0009115]	mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d3ns1a2_d2w3rc2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3ns1b1_d5fxeb1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d3ns1j1_d3vr9f1__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	xanthine catabolic process [GO:0009115]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d3ns1k1_d5fxea1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d3ns1l1_d1sb3a1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]
d3nsca2_d1rzqa2__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3nsda2_d3n2jg___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3nsfa1_d2vw7a1__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3nsfa2_d1hawa1__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3nsfa2_d5d4ha1__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3nsib__d4mbea___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]; chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]; histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]		histone deubiquitination [GO:0016578]; histone H3-K4 methylation [GO:0051568]; histone H3-K79 methylation [GO:0034729]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	DUBm complex [GO:0071819]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; SAGA complex [GO:0000124]; transcription export complex 2 [GO:0070390]	calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; enzyme activator activity [GO:0008047]; transcription coactivator activity [GO:0003713]
d3nsoa1_d4etob___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]	actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell leading edge [GO:0031252]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin-dependent ATPase activity [GO:0030898]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]; actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]		actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]	cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell leading edge [GO:0031252]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]	calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270]	actin binding [GO:0003779]; actin-dependent ATPase activity [GO:0030898]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]
d3nssb__d1ivcb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3ntcl1_d3ay4b1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		IgG binding [GO:0019864]
d3ntga2_d4xvag___1	Metazoa	Fungi	Chordata	Ascomycota	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3ntgc2_d5jhyb2__1	Metazoa	Fungi	Chordata	Ascomycota	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	extracellular region [GO:0005576]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3ntgd2_d1beja___1	Metazoa	Fungi	Chordata	Ascomycota	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3ntlb__d2p9ya___1			Proteobacteria	Deinococcus-Thermus		catalytic activity [GO:0003824]						catalytic activity [GO:0003824]
d3ntya__d1vp5b___1	Metazoa		Chordata	Thermotogae	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity [GO:0047006]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; indanol dehydrogenase activity [GO:0047718]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; bile acid and bile salt transport [GO:0015721]; bile acid metabolic process [GO:0008206]; cellular response to jasmonic acid stimulus [GO:0071395]; cholesterol homeostasis [GO:0042632]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; intestinal cholesterol absorption [GO:0030299]; oxidation-reduction process [GO:0055114]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; protein homooligomerization [GO:0051260]; response to organophosphorus [GO:0046683]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	bile acid and bile salt transport [GO:0015721]; bile acid metabolic process [GO:0008206]; cellular response to jasmonic acid stimulus [GO:0071395]; cholesterol homeostasis [GO:0042632]; daunorubicin metabolic process [GO:0044597]; digestion [GO:0007586]; doxorubicin metabolic process [GO:0044598]; epithelial cell differentiation [GO:0030855]; intestinal cholesterol absorption [GO:0030299]; oxidation-reduction process [GO:0055114]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; protein homooligomerization [GO:0051260]; response to organophosphorus [GO:0046683]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity [GO:0047006]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase (B-specific) activity [GO:0047042]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; carboxylic acid binding [GO:0031406]; indanol dehydrogenase activity [GO:0047718]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; steroid dehydrogenase activity [GO:0016229]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3nu1a__d3hh8a___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; zinc ion transport [GO:0006829]		cell adhesion [GO:0007155]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; zinc ion transport [GO:0006829]		plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3nu3b__d3oqka___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d3nu4b__d1xn2b___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3nu4b__d2i4ub___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3nu5a__d1bvea___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3nu5b__d4ckuf___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3nu7b__d2d63a___1			Proteobacteria	Proteobacteria	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; cell wall organization [GO:0071555]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]; polysaccharide biosynthetic process [GO:0000271]; UDP-glucuronate biosynthetic process [GO:0006065]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cell wall organization [GO:0071555]; lipopolysaccharide biosynthetic process [GO:0009103]; O antigen biosynthetic process [GO:0009243]; polysaccharide biosynthetic process [GO:0000271]; UDP-glucuronate biosynthetic process [GO:0006065]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d3nuga__d3i3od___1			Proteobacteria	Firmicutes	pyridoxal 4-dehydrogenase activity [GO:0050235]; vitamin B6 catabolic process [GO:0042820]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	vitamin B6 catabolic process [GO:0042820]				pyridoxal 4-dehydrogenase activity [GO:0050235]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3nugb__d3czrb2__1		Metazoa	Proteobacteria	Chordata	pyridoxal 4-dehydrogenase activity [GO:0050235]; vitamin B6 catabolic process [GO:0042820]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	vitamin B6 catabolic process [GO:0042820]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	pyridoxal 4-dehydrogenase activity [GO:0050235]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d3nuia1_d1w23a___1			Proteobacteria	Firmicutes	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]		L-serine biosynthetic process [GO:0006564]		cytoplasm [GO:0005737]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]
d3nuja__d1apwe___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3nujb__d5hcoa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3nuob__d1hvka___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3nuob__d5p4ga___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3nv1a__d5gm4b___1	Metazoa	Fungi	Chordata	Ascomycota	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	cellulose catabolic process [GO:0030245]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	cellulase activity [GO:0008810]
d3nv2a__d1v6me___1	Metazoa	Viridiplantae	Chordata	Streptophyta	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3nv4a__d4k1zc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3nv8a__d3ps7a___1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; manganese ion binding [GO:0030145]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; protein homooligomerization [GO:0051260]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; protein homooligomerization [GO:0051260]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; manganese ion binding [GO:0030145]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3nv8b1_d5hudb___1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; manganese ion binding [GO:0030145]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; protein homooligomerization [GO:0051260]	chorismate metabolic process [GO:0046417]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; protein homooligomerization [GO:0051260]	chorismate metabolic process [GO:0046417]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; manganese ion binding [GO:0030145]	
d3nvub__d3kxca___1		Metazoa	Firmicutes	Chordata	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	cis-Golgi network membrane [GO:0033106]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; TRAPP complex [GO:0030008]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]	signal transduction [GO:0007165]	COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]	integral component of membrane [GO:0016021]	cis-Golgi network membrane [GO:0033106]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; TRAPP complex [GO:0030008]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d3nvub__d3m0ba___1			Firmicutes	Firmicutes	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	signal transduction [GO:0007165]	signal transduction [GO:0007165]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3nvva1_d1j7aa___1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3nvva1_d1t3qa2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	oxidoreductase activity [GO:0016491]
d3nvvb1_d1w1sa2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	extracellular space [GO:0005615]; cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]	xanthine catabolic process [GO:0009115]	cytokinin metabolic process [GO:0009690]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	extracellular space [GO:0005615]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]
d3nvvb2_d1n63f1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3nvvj1_d1oqrb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3nvwa1_d5h57b___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; etioplast stroma [GO:0009578]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; electron transport chain [GO:0022900]	xanthine catabolic process [GO:0009115]	electron transport chain [GO:0022900]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; etioplast stroma [GO:0009578]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3nvwb2_d1jrpg3__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3nvwc1_d1n63b1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3nvwj1_d2wu5j1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	xanthine catabolic process [GO:0009115]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d3nvwj2_d1qj2a4__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	
d3nvwk2_d1n60f1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3nvya2_d2w3sa2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3nvyb1_d5fxdb1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d3nvyb2_d1jrpe3__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3nvyc2_d1t3qb2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	oxidoreductase activity [GO:0016491]
d3nvyj1_d3w5ud___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	xanthine catabolic process [GO:0009115]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	chloroplast thylakoid membrane protein complex [GO:0098807]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d3nvyk1_d2vfra2__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	membrane [GO:0016020]; D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	membrane [GO:0016020]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]
d3nvyk2_d1ffvf1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3nvzb1_d2w3rg3__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3nvzl1_d1rm6d1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]
d3nw3c__d3hmba___1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; cell wall organization [GO:0071555]; establishment of competence for transformation [GO:0030420]; peptidoglycan catabolic process [GO:0009253]; peptidoglycan turnover [GO:0009254]; sporulation resulting in formation of a cellular spore [GO:0030435]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cell wall organization [GO:0071555]; establishment of competence for transformation [GO:0030420]; peptidoglycan catabolic process [GO:0009253]; peptidoglycan turnover [GO:0009254]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]
d3nw4a__d1j3qb___1			Proteobacteria	Euryarchaeota	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]
d3nw9a__d2pt6a___1	Metazoa		Chordata	Apicomplexa	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	cytosol [GO:0005829]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	spermidine synthase activity [GO:0004766]
d3nwba__d3hcba___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d3nwvc__d5kkea___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3nx0b__d2o9ux___1	Metazoa	Viridiplantae	Chordata	Streptophyta	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; tertiary granule lumen [GO:1904724]; amyloid-beta binding [GO:0001540]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; identical protein binding [GO:0042802]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; cellular protein metabolic process [GO:0044267]; defense response [GO:0006952]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of collagen catabolic process [GO:0010711]; negative regulation of elastin catabolic process [GO:0060311]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]; post-translational protein modification [GO:0043687]; regulation of tissue remodeling [GO:0034103]; supramolecular fiber organization [GO:0097435]		cellular protein metabolic process [GO:0044267]; defense response [GO:0006952]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of collagen catabolic process [GO:0010711]; negative regulation of elastin catabolic process [GO:0060311]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]; post-translational protein modification [GO:0043687]; regulation of tissue remodeling [GO:0034103]; supramolecular fiber organization [GO:0097435]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; tertiary granule lumen [GO:1904724]		amyloid-beta binding [GO:0001540]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; identical protein binding [GO:0042802]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]	
d3nx2a__d3flla___1		Metazoa	Proteobacteria	Arthropoda	carboxy-lyase activity [GO:0016831]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]		vasodilation [GO:0042311]		extracellular region [GO:0005576]	carboxy-lyase activity [GO:0016831]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d3nx7a__d3hyga___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; negative regulation of cold-induced thermogenesis [GO:0120163]; proteolysis [GO:0006508]; tooth eruption [GO:0044691]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	extracellular matrix binding [GO:0050840]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]
d3nxaa__d1lkja___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; response to calcium ion [GO:0051592]	cellular bud [GO:0005933]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; central plaque of spindle pole body [GO:0005823]; cytoplasm [GO:0005737]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; mitogen-activated protein kinase binding [GO:0051019]; calcium-mediated signaling [GO:0019722]; cell budding [GO:0007114]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; karyogamy involved in conjugation with cellular fusion [GO:0000742]; lysosomal microautophagy [GO:0016237]; phosphatidylinositol biosynthetic process [GO:0006661]; protein import into nucleus [GO:0006606]; receptor-mediated endocytosis [GO:0006898]; regulation of membrane tubulation [GO:1903525]; spindle pole body organization [GO:0051300]; vacuole fusion, non-autophagic [GO:0042144]	response to calcium ion [GO:0051592]	calcium-mediated signaling [GO:0019722]; cell budding [GO:0007114]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; karyogamy involved in conjugation with cellular fusion [GO:0000742]; lysosomal microautophagy [GO:0016237]; phosphatidylinositol biosynthetic process [GO:0006661]; protein import into nucleus [GO:0006606]; receptor-mediated endocytosis [GO:0006898]; regulation of membrane tubulation [GO:1903525]; spindle pole body organization [GO:0051300]; vacuole fusion, non-autophagic [GO:0042144]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	cellular bud [GO:0005933]; cellular bud neck [GO:0005935]; cellular bud tip [GO:0005934]; central plaque of spindle pole body [GO:0005823]; cytoplasm [GO:0005737]; incipient cellular bud site [GO:0000131]; mating projection tip [GO:0043332]	calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mitogen-activated protein kinase binding [GO:0051019]
d3nxab__d2luxa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; response to calcium ion [GO:0051592]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]; ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]; intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	response to calcium ion [GO:0051592]	intracellular signal transduction [GO:0035556]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of heart contraction [GO:0008016]; substantia nigra development [GO:0021762]; toll-like receptor signaling pathway [GO:0002224]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; M band [GO:0031430]; neuron projection [GO:0043005]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; sarcoplasmic reticulum [GO:0016529]; Z disc [GO:0030018]	calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]	ATPase binding [GO:0051117]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; S100 protein binding [GO:0044548]
d3nxba__d4whwa1__1	Metazoa	Metazoa	Chordata	Chordata	CERF complex [GO:0090537]; nucleus [GO:0005634]; apoptotic DNA fragmentation [GO:0006309]; ATP-dependent chromatin remodeling [GO:0043044]; cytoskeleton organization [GO:0007010]; cytoskeleton-dependent cytokinesis [GO:0061640]; execution phase of apoptosis [GO:0097194]; vesicle-mediated transport [GO:0016192]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	apoptotic DNA fragmentation [GO:0006309]; ATP-dependent chromatin remodeling [GO:0043044]; cytoskeleton-dependent cytokinesis [GO:0061640]; cytoskeleton organization [GO:0007010]; execution phase of apoptosis [GO:0097194]; vesicle-mediated transport [GO:0016192]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	CERF complex [GO:0090537]; nucleus [GO:0005634]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]
d3nxbb__d5igka1__1	Metazoa	Metazoa	Chordata	Chordata	CERF complex [GO:0090537]; nucleus [GO:0005634]; apoptotic DNA fragmentation [GO:0006309]; ATP-dependent chromatin remodeling [GO:0043044]; cytoskeleton organization [GO:0007010]; cytoskeleton-dependent cytokinesis [GO:0061640]; execution phase of apoptosis [GO:0097194]; vesicle-mediated transport [GO:0016192]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	apoptotic DNA fragmentation [GO:0006309]; ATP-dependent chromatin remodeling [GO:0043044]; cytoskeleton-dependent cytokinesis [GO:0061640]; cytoskeleton organization [GO:0007010]; execution phase of apoptosis [GO:0097194]; vesicle-mediated transport [GO:0016192]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	CERF complex [GO:0090537]; nucleus [GO:0005634]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]
d3nxta__d3ia4d___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3ny7b__d2mr8a1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	hydrolase activity, acting on ester bonds [GO:0016788]; phosphopantetheine binding [GO:0031177]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]; lipid biosynthetic process [GO:0008610]; response to drug [GO:0042493]	biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acyl binding [GO:0000035]; acyl carrier activity [GO:0000036]; lipid binding [GO:0008289]; phosphopantetheine binding [GO:0031177]	hydrolase activity, acting on ester bonds [GO:0016788]; phosphopantetheine binding [GO:0031177]
d3nyda1_d1q6fa___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			endo-1,4-beta-xylanase activity [GO:0031176]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d3nydb__d5g5kb___1	Fungi		Ascomycota	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cytoplasm [GO:0005737]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]	endo-1,4-beta-xylanase activity [GO:0031176]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]
d3nyka__d3plyc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3nyzb__d3p60a___1			Crenarchaeota	Euryarchaeota	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3nz8l1_d1yeih1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3nz8l2_d1cr9h1__1												
d3nzcx__d4klxa1__1	Fungi		Ascomycota	Actinobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]
d3nzhl1_d4kk5f2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3nzhl2_d1duza1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3nzja__d1irum___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzje__d4fzgf___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzjh__d5l60w___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzjk__d1ecjb2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]
d3nzjo__d5d0zk___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzjt__d4qwfc___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzjv__d3sdkc___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzjx__d1z7qh1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzwg__d5l65k___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzwj__d4qvyq___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzwl__d4no6y___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzwl__d5l60g___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzwm__d1e94a___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]
d3nzwn__d4qw0q___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzws__d2fnyp___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	
d3nzwz__d2zcyk___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzx1__d5l5rg___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzxc__d4qzxv___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzxj__d4quxo___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzxp__d5cz8f___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3nzxv__d1ecgb2__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	amidophosphoribosyltransferase activity [GO:0004044]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; transferase activity, transferring glycosyl groups [GO:0016757]
d3nzxx__d3mjic___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	penicillin amidase activity [GO:0008953]
d3o05c__d2cz5b___1	Fungi		Ascomycota	Euryarchaeota	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	glutaminase complex [GO:1903600]		amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3o05c__d5lnvb___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]; amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]	glutaminase complex [GO:1903600]	cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3o06b__d3n2ma1__1	Fungi		Ascomycota	Apicomplexa	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	glutaminase complex [GO:1903600]		amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3o08a2_d5gn5a2__1	Fungi		Ascomycota		cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cell [GO:0005623]		ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d3o08b1_d1gllo2__1	Fungi		Ascomycota	Proteobacteria	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	cell [GO:0005623]	cytosol [GO:0005829]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d3o0db__d1ji3b___1	Fungi		Ascomycota	Firmicutes	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	metal ion binding [GO:0046872]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]
d3o0dc__d3fvtd___1	Fungi		Ascomycota	Firmicutes	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	acetylesterase activity [GO:0008126]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	acetylesterase activity [GO:0008126]
d3o0de__d2b4kb2__1	Fungi		Ascomycota	Proteobacteria	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	lipid catabolic process [GO:0016042]				triglyceride lipase activity [GO:0004806]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d3o0gd__d4nstb1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; protein kinase 5 complex [GO:0016533]; actin filament binding [GO:0051015]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; ephrin receptor binding [GO:0046875]; ionotropic glutamate receptor binding [GO:0035255]; kinase activity [GO:0016301]; protease binding [GO:0002020]; protein kinase activator activity [GO:0030295]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; brain development [GO:0007420]; cerebellum development [GO:0021549]; embryo development ending in birth or egg hatching [GO:0009792]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; layer formation in cerebral cortex [GO:0021819]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of axon extension [GO:0030517]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of receptor biosynthetic process [GO:0010870]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of macroautophagy [GO:0016241]; regulation of neuron differentiation [GO:0045664]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of synaptic vesicle cycle [GO:0098693]; rhythmic process [GO:0048511]; serine phosphorylation of STAT protein [GO:0042501]; superior olivary nucleus maturation [GO:0021722]	cyclin K-CDK12 complex [GO:0002944]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; brain development [GO:0007420]; cerebellum development [GO:0021549]; embryo development ending in birth or egg hatching [GO:0009792]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; layer formation in cerebral cortex [GO:0021819]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of axon extension [GO:0030517]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of receptor biosynthetic process [GO:0010870]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of macroautophagy [GO:0016241]; regulation of neuron differentiation [GO:0045664]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of synaptic vesicle cycle [GO:0098693]; rhythmic process [GO:0048511]; serine phosphorylation of STAT protein [GO:0042501]; superior olivary nucleus maturation [GO:0021722]	mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	axon [GO:0030424]; contractile fiber [GO:0043292]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; protein kinase 5 complex [GO:0016533]	cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin K-CDK12 complex [GO:0002944]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	actin filament binding [GO:0051015]; alpha-tubulin binding [GO:0043014]; beta-tubulin binding [GO:0048487]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; ephrin receptor binding [GO:0046875]; ionotropic glutamate receptor binding [GO:0035255]; kinase activity [GO:0016301]; protease binding [GO:0002020]; protein kinase activator activity [GO:0030295]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activator activity [GO:0043539]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]
d3o0ja__d5tzhb1__1	Metazoa	Metazoa	Chordata	Chordata	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d3o0rl1_d2dava1__1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]; aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	cytosol [GO:0005829]; myofibril [GO:0030016]; myosin filament [GO:0032982]; actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	cytosol [GO:0005829]; myofibril [GO:0030016]; myosin filament [GO:0032982]	cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]	actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]
d3o11a1_d4wi8b2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3o11l2_d1egjl2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3o11l2_d1xeda1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; polymeric immunoglobulin receptor activity [GO:0001792]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc receptor signaling pathway [GO:0038093]; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [GO:0002415]; neutrophil degranulation [GO:0043312]; receptor clustering [GO:0043113]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc receptor signaling pathway [GO:0038093]; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [GO:0002415]; neutrophil degranulation [GO:0043312]; receptor clustering [GO:0043113]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	polymeric immunoglobulin receptor activity [GO:0001792]
d3o1ba1_d4rwta2__1	Fungi	Metazoa	Ascomycota	Arthropoda	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	cell [GO:0005623]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]	ATP binding [GO:0005524]
d3o1ba2_d3bexf1__1	Fungi		Ascomycota	Thermotogae	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	coenzyme A biosynthetic process [GO:0015937]	cell [GO:0005623]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d3o1ga__d1deua___1	Metazoa	Metazoa	Chordata	Chordata	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; carboxypeptidase activity [GO:0004180]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; angiotensin maturation [GO:0002003]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; negative regulation of neuron projection development [GO:0010977]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of protein binding [GO:0032091]; neutrophil degranulation [GO:0043312]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron apoptotic process [GO:0043525]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of neuron death [GO:1901214]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	angiotensin maturation [GO:0002003]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; negative regulation of neuron projection development [GO:0010977]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of protein binding [GO:0032091]; neutrophil degranulation [GO:0043312]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron apoptotic process [GO:0043525]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of neuron death [GO:1901214]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]	carboxypeptidase activity [GO:0004180]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]
d3o1kb__d1wura___1			Proteobacteria	Deinococcus-Thermus	dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydroneopterin aldolase activity [GO:0004150]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d3o1kc__d1vaxe2__1			Proteobacteria		dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]		folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydroneopterin aldolase activity [GO:0004150]	
d3o1pa__d1os7a___1			Proteobacteria	Proteobacteria	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	cytoplasm [GO:0005737]; L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]; sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]		cytoplasm [GO:0005737]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]	L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]
d3o1ua__d2vcma___1		Fungi	Proteobacteria	Ascomycota	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]; penicillin biosynthetic process [GO:0042318]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	penicillin biosynthetic process [GO:0042318]			1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]
d3o1va__d5ph5a___1		Metazoa	Proteobacteria	Chordata	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]		blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d3o1xa__d5i2ea___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d3o1ya__d3tyib___1	Metazoa	Fungi	Chordata	Ascomycota	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3o20a__d2fyud1__1	Metazoa	Metazoa	Chordata	Chordata	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	apoptotic process [GO:0006915]; cytochrome c-heme linkage [GO:0018063]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytochrome complex [GO:0070069]; cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3o26a__d3pk0b1__1	Viridiplantae		Streptophyta	Actinobacteria	NADP binding [GO:0050661]; salutaridine reductase (NADPH) activity [GO:0047037]; morphine biosynthetic process [GO:0097295]	metal ion binding [GO:0046872]	morphine biosynthetic process [GO:0097295]				NADP binding [GO:0050661]; salutaridine reductase (NADPH) activity [GO:0047037]	metal ion binding [GO:0046872]
d3o2bc__d4yjma___1			Proteobacteria	Proteobacteria	chaperone binding [GO:0051087]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]			chaperone binding [GO:0051087]	
d3o2dl1_d3c60b1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d3o2ha__d1dd3a2__1			Proteobacteria	Thermotogae	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cytosolic large ribosomal subunit [GO:0022625]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	translation [GO:0006412]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	cytosolic large ribosomal subunit [GO:0022625]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	structural constituent of ribosome [GO:0003735]
d3o2la1_d1qoxa___1	Fungi		Ascomycota	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]			endo-1,4-beta-xylanase activity [GO:0031176]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3o2oa__d3g1bb___1			Proteobacteria	Proteobacteria	chaperone binding [GO:0051087]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]			chaperone binding [GO:0051087]	
d3o2ob__d4yjxa___1			Proteobacteria	Proteobacteria	chaperone binding [GO:0051087]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]			chaperone binding [GO:0051087]	
d3o2of__d1dd4a2__1			Proteobacteria	Thermotogae	chaperone binding [GO:0051087]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytosolic large ribosomal subunit [GO:0022625]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]	chaperone binding [GO:0051087]	structural constituent of ribosome [GO:0003735]
d3o2og__d4ykad___1			Proteobacteria	Proteobacteria	chaperone binding [GO:0051087]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to heat [GO:0009408]	protein catabolic process [GO:0030163]; proteolysis [GO:0006508]			chaperone binding [GO:0051087]	
d3o2wl1_d4weue___1		Metazoa		Chordata								
d3o2xa1_d1os2e1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3o2xa1_d5uu8a___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3o2xc1_d4j4mb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3o2xd1_d5wr3a___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3o3aa1_d2rfxa2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3o3aa1_d4nqca1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3o3ad1_d4n0fa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3o3ad1_d5ksba1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3o3ba2_d1bfoh2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3o3bb1_d5alcl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3o3bd1_d3bwaa2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3o3bd2_d3wxwl___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; intrinsic component of plasma membrane [GO:0031226]; plasma membrane [GO:0005886]; adipokinetic hormone receptor activity [GO:0097003]; adiponectin binding [GO:0055100]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; signaling receptor activity [GO:0038023]; adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; female pregnancy [GO:0007565]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; negative regulation of cell growth [GO:0030308]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of glucose import [GO:0046326]; regulation of fatty acid biosynthetic process [GO:0042304]; response to nutrient [GO:0007584]; vascular wound healing [GO:0061042]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; female pregnancy [GO:0007565]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; negative regulation of cell growth [GO:0030308]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of glucose import [GO:0046326]; regulation of fatty acid biosynthetic process [GO:0042304]; response to nutrient [GO:0007584]; vascular wound healing [GO:0061042]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; intrinsic component of plasma membrane [GO:0031226]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	adipokinetic hormone receptor activity [GO:0097003]; adiponectin binding [GO:0055100]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; signaling receptor activity [GO:0038023]
d3o3be1_d5jdsa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3o3da2_d1mcha2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3o3db1_d5y11b2__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; virion [GO:0019012]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; virion [GO:0019012]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3o3dd1_d1fo0h2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3o3ea2_d4wo4d1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3o3ee1_d4xnml2__1	Metazoa		Chordata	Negarnaviricota	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d3o3fa__d1rtia1__1			Thermotogae		cytoplasm [GO:0005737]; ribonuclease H2 complex [GO:0032299]; manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; mismatch repair [GO:0006298]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA replication, removal of RNA primer [GO:0043137]; mismatch repair [GO:0006298]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	cytoplasm [GO:0005737]; ribonuclease H2 complex [GO:0032299]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3o3lb__d3d1qa___1			Firmicutes	Firmicutes	protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]					protein tyrosine phosphatase activity [GO:0004725]	protein tyrosine phosphatase activity [GO:0004725]
d3o3qa__d3ud8b___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3o3qa__d8i1ba___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	autophagosome [GO:0005776]; cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; vesicle [GO:0031982]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; astrocyte activation [GO:0048143]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-6 production [GO:0032635]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; memory [GO:0007613]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of branching morphogenesis of a nerve [GO:2000173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of glutamate secretion [GO:0014050]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of synaptic transmission [GO:0050805]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell death [GO:0010942]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; social behavior [GO:0035176]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; astrocyte activation [GO:0048143]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-6 production [GO:0032635]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; memory [GO:0007613]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of branching morphogenesis of a nerve [GO:2000173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of glutamate secretion [GO:0014050]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of synaptic transmission [GO:0050805]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell death [GO:0010942]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; social behavior [GO:0035176]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	autophagosome [GO:0005776]; cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; vesicle [GO:0031982]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d3o3qc__d2p23a___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of bile acid biosynthetic process [GO:0070858]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of bile acid biosynthetic process [GO:0070858]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]
d3o48a1_d2c2la1__1	Fungi	Metazoa	Ascomycota	Chordata	integral component of mitochondrial outer membrane [GO:0031307]; integral component of peroxisomal membrane [GO:0005779]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; apoptotic process [GO:0006915]; autophagy of mitochondrion [GO:0000422]; chronological cell aging [GO:0001300]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; peroxisome fission [GO:0016559]; peroxisome organization [GO:0007031]; positive regulation of mitochondrial fission [GO:0090141]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	apoptotic process [GO:0006915]; autophagy of mitochondrion [GO:0000422]; chronological cell aging [GO:0001300]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; peroxisome fission [GO:0016559]; peroxisome organization [GO:0007031]; positive regulation of mitochondrial fission [GO:0090141]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	integral component of mitochondrial outer membrane [GO:0031307]; integral component of peroxisomal membrane [GO:0005779]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3o4fc__d5p9ya___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; spermine synthase activity [GO:0016768]; thermospermine synthase activity [GO:0010487]; spermidine biosynthetic process [GO:0008295]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	spermidine biosynthetic process [GO:0008295]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytosol [GO:0005829]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	cadaverine aminopropyltransferase activity [GO:0043918]; spermidine synthase activity [GO:0004766]; spermine synthase activity [GO:0016768]; thermospermine synthase activity [GO:0010487]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d3o4ga1_d4bcca1__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d3o4ga2_d1mx1b___1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]		angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	serine-type peptidase activity [GO:0008236]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d3o4gc1_d1uoqa1__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d3o4gc2_d4ke9d___1			Crenarchaeota	Firmicutes	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	acylglycerol lipase activity [GO:0047372]			cytoplasm [GO:0005737]		serine-type peptidase activity [GO:0008236]	acylglycerol lipase activity [GO:0047372]
d3o4gd1_d1o6ga1__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	serine-type peptidase activity [GO:0008236]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d3o4ld1_d3s34l1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3o4ld1_d3tm6d1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3o4le1_d1jtob___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3o4le1_d5l9dl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3o4ma__d1m8te___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]; bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d3o4rd__d1v8bd1__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 3-keto sterol reductase activity [GO:0000253]; alcohol dehydrogenase [NAD(P)+] activity [GO:0018455]; carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; alcohol metabolic process [GO:0006066]; cellular ketone metabolic process [GO:0042180]; oxidation-reduction process [GO:0055114]; protein targeting to peroxisome [GO:0006625]; protein tetramerization [GO:0051262]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; adenosylhomocysteinase activity [GO:0004013]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353]	alcohol metabolic process [GO:0006066]; cellular ketone metabolic process [GO:0042180]; oxidation-reduction process [GO:0055114]; protein targeting to peroxisome [GO:0006625]; protein tetramerization [GO:0051262]; steroid metabolic process [GO:0008202]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	cytosol [GO:0005829]	3-keto sterol reductase activity [GO:0000253]; alcohol dehydrogenase [NAD(P)+] activity [GO:0018455]; carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]	adenosylhomocysteinase activity [GO:0004013]
d3o4wa1_d3ldna2__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	cell [GO:0005623]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3o4wb1_d5aqla1__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3o4wb2_d5br9c1__1	Fungi		Ascomycota	Proteobacteria	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	cell [GO:0005623]		ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]	
d3o5aa1_d3egwa1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]	integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]; anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]	anaerobic respiration [GO:0009061]	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	integral component of plasma membrane [GO:0005887]; NarGHI complex [GO:0044799]; nitrate reductase complex [GO:0009325]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate reductase activity [GO:0008940]
d3o5ba1_d1h1va2__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell [GO:0005623]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3o5bb2_d4br2a1__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adenosine-diphosphatase activity [GO:0043262]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	cell [GO:0005623]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]	adenosine-diphosphatase activity [GO:0043262]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]
d3o5ca2_d3zowr___1			Proteobacteria	Proteobacteria	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3o5cb1_d1m6zb1__1			Proteobacteria	Proteobacteria	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3o5ga1_d4iq2b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	calcium channel complex [GO:0034704]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018]; calcium channel inhibitor activity [GO:0019855]; cyclic nucleotide binding [GO:0030551]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; signaling receptor binding [GO:0005102]; 'de novo' protein folding [GO:0006458]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; chaperone-mediated protein folding [GO:0061077]; insulin secretion [GO:0030073]; ion transmembrane transport [GO:0034220]; negative regulation of heart rate [GO:0010459]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of release of sequestered calcium ion into cytosol [GO:0051280]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neuronal action potential propagation [GO:0019227]; positive regulation of axon regeneration [GO:0048680]; positive regulation of sequestering of calcium ion [GO:0051284]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; release of sequestered calcium ion into cytosol [GO:0051209]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to redox state [GO:0051775]; response to vitamin E [GO:0033197]; smooth muscle contraction [GO:0006939]; T cell proliferation [GO:0042098]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	'de novo' protein folding [GO:0006458]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; chaperone-mediated protein folding [GO:0061077]; insulin secretion [GO:0030073]; ion transmembrane transport [GO:0034220]; negative regulation of heart rate [GO:0010459]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of release of sequestered calcium ion into cytosol [GO:0051280]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neuronal action potential propagation [GO:0019227]; positive regulation of axon regeneration [GO:0048680]; positive regulation of sequestering of calcium ion [GO:0051284]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; release of sequestered calcium ion into cytosol [GO:0051209]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to redox state [GO:0051775]; response to vitamin E [GO:0033197]; smooth muscle contraction [GO:0006939]; T cell proliferation [GO:0042098]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	calcium channel complex [GO:0034704]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	calcium channel inhibitor activity [GO:0019855]; cyclic nucleotide binding [GO:0030551]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; signaling receptor binding [GO:0005102]
d3o5ka1_d1b6cc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]; activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]; 'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	'de novo' protein folding [GO:0006458]; amyloid fibril formation [GO:1990000]; calcium ion transmembrane transport [GO:0070588]; chaperone-mediated protein folding [GO:0061077]; heart morphogenesis [GO:0003007]; heart trabecula formation [GO:0060347]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein folding [GO:0006457]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of immune response [GO:0050776]; regulation of protein localization [GO:0032880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; SMAD protein complex assembly [GO:0007183]; supramolecular fiber organization [GO:0097435]; T cell activation [GO:0042110]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytoplasmic side of membrane [GO:0098562]; cytosol [GO:0005829]; extrinsic component of organelle membrane [GO:0031312]; membrane [GO:0016020]; ryanodine receptor complex [GO:1990425]; sarcoplasmic reticulum [GO:0016529]; terminal cisterna [GO:0014802]; Z disc [GO:0030018]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	activin binding [GO:0048185]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; macrolide binding [GO:0005527]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; SMAD binding [GO:0046332]; transforming growth factor beta receptor binding [GO:0005160]; type I transforming growth factor beta receptor binding [GO:0034713]
d3o5ka1_d3ni6b___1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]		FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d3o5kb1_d1u79e___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	chloroplast [GO:0009507]; chloroplast thylakoid lumen [GO:0009543]; plastid [GO:0009536]; thylakoid lumen [GO:0031977]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	chloroplast [GO:0009507]; chloroplast thylakoid lumen [GO:0009543]; plastid [GO:0009536]; thylakoid lumen [GO:0031977]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d3o5kb1_d5hwca1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d3o5mb1_d1zk6a___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	plasma membrane [GO:0005886]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]; protein transport [GO:0015031]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	protein folding [GO:0006457]; protein transport [GO:0015031]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	plasma membrane [GO:0005886]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d3o5oa1_d4drha___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d3o5pa1_d1q1ca1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein-containing complex localization [GO:0031503]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein-containing complex localization [GO:0031503]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]
d3o5qa1_d4dz3a1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]	metal ion binding [GO:0046872]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; response to bacterium [GO:0009617]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]		FK506 binding [GO:0005528]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	metal ion binding [GO:0046872]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d3o5sa__d1qooc___1		Viridiplantae	Firmicutes	Streptophyta	extracellular region [GO:0005576]; licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		licheninase activity [GO:0042972]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3o5ub__d3t63b___1			Actinobacteria	Proteobacteria	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]; aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d3o65b__d4icub___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; alpha-tubulin binding [GO:0043014]; chaperone binding [GO:0051087]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; microtubule [GO:0005874]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	alpha-tubulin binding [GO:0043014]; chaperone binding [GO:0051087]
d3o69b__d1x84b2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; GDP-mannose hydrolase activity [GO:0052751]; magnesium ion binding [GO:0000287]; nucleoside phosphate metabolic process [GO:0006753]; ribose phosphate metabolic process [GO:0019693]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	nucleoside phosphate metabolic process [GO:0006753]; ribose phosphate metabolic process [GO:0019693]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	GDP-mannose hydrolase activity [GO:0052751]; magnesium ion binding [GO:0000287]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]
d3o6fa2_d1oayh___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		
d3o6fc1_d1fbil1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3o6fd2_d1otuc1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3o6fe1_d4pjhc1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3o6fh1_d2gj6e1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3o6ha1_d3tcfc___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]
d3o6ha1_d4pgnc___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d3o6ia1_d5h8na___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; NMDA selective glutamate receptor complex [GO:0017146]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; glutamate-gated calcium ion channel activity [GO:0022849]; NMDA glutamate receptor activity [GO:0004972]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; zinc ion binding [GO:0008270]; activation of cysteine-type endopeptidase activity [GO:0097202]; brain development [GO:0007420]; calcium ion transmembrane import into cytosol [GO:0097553]; chemical synaptic transmission [GO:0007268]; directional locomotion [GO:0033058]; dopamine metabolic process [GO:0042417]; excitatory chemical synaptic transmission [GO:0098976]; excitatory postsynaptic potential [GO:0060079]; glutamate receptor signaling pathway [GO:0007215]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of protein catabolic process [GO:0042177]; neurogenesis [GO:0022008]; positive regulation of apoptotic process [GO:0043065]; protein localization to postsynaptic membrane [GO:1903539]; regulation of NMDA receptor activity [GO:2000310]; regulation of synaptic plasticity [GO:0048167]; response to amphetamine [GO:0001975]; response to ethanol [GO:0045471]; response to wounding [GO:0009611]; sensory perception of pain [GO:0019233]; serotonin metabolic process [GO:0042428]; sleep [GO:0030431]; startle response [GO:0001964]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	activation of cysteine-type endopeptidase activity [GO:0097202]; brain development [GO:0007420]; calcium ion transmembrane import into cytosol [GO:0097553]; chemical synaptic transmission [GO:0007268]; directional locomotion [GO:0033058]; dopamine metabolic process [GO:0042417]; excitatory chemical synaptic transmission [GO:0098976]; excitatory postsynaptic potential [GO:0060079]; glutamate receptor signaling pathway [GO:0007215]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of protein catabolic process [GO:0042177]; neurogenesis [GO:0022008]; positive regulation of apoptotic process [GO:0043065]; protein localization to postsynaptic membrane [GO:1903539]; regulation of NMDA receptor activity [GO:2000310]; regulation of synaptic plasticity [GO:0048167]; response to amphetamine [GO:0001975]; response to ethanol [GO:0045471]; response to wounding [GO:0009611]; sensory perception of pain [GO:0019233]; serotonin metabolic process [GO:0042428]; sleep [GO:0030431]; startle response [GO:0001964]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendritic spine [GO:0043197]; endoplasmic reticulum [GO:0005783]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; NMDA selective glutamate receptor complex [GO:0017146]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synaptic membrane [GO:0097060]; synaptic vesicle [GO:0008021]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	amyloid-beta binding [GO:0001540]; glutamate-gated calcium ion channel activity [GO:0022849]; glutamate receptor activity [GO:0008066]; NMDA glutamate receptor activity [GO:0004972]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; zinc ion binding [GO:0008270]
d3o6oa1_d1zxnb1__1		Metazoa		Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; viral integration complex [GO:0019035]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; DNA-dependent ATPase activity [GO:0008094]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; magnesium ion binding [GO:0000287]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]; apoptotic chromosome condensation [GO:0030263]; cellular response to DNA damage stimulus [GO:0006974]; chromosome segregation [GO:0007059]; DNA ligation [GO:0006266]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; female meiotic nuclear division [GO:0007143]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic DNA integrity checkpoint [GO:0044774]; negative regulation of DNA duplex unwinding [GO:1905463]; positive regulation of apoptotic process [GO:0043065]; positive regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; resolution of meiotic recombination intermediates [GO:0000712]; rhythmic process [GO:0048511]; sister chromatid segregation [GO:0000819]	cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	apoptotic chromosome condensation [GO:0030263]; cellular response to DNA damage stimulus [GO:0006974]; chromosome segregation [GO:0007059]; DNA ligation [GO:0006266]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; female meiotic nuclear division [GO:0007143]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic DNA integrity checkpoint [GO:0044774]; negative regulation of DNA duplex unwinding [GO:1905463]; positive regulation of apoptotic process [GO:0043065]; positive regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045870]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; resolution of meiotic recombination intermediates [GO:0000712]; rhythmic process [GO:0048511]; sister chromatid segregation [GO:0000819]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	condensed chromosome [GO:0000793]; cytoplasm [GO:0005737]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; viral integration complex [GO:0019035]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA binding, bending [GO:0008301]; DNA-dependent ATPase activity [GO:0008094]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; magnesium ion binding [GO:0000287]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; ubiquitin binding [GO:0043130]
d3o6oa1_d4xdma___1					cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; aggregation involved in sorocarp development [GO:0031152]; cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	aggregation involved in sorocarp development [GO:0031152]; cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d3o6tc__d2pmtc2__1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; S-nitrosoglutathione reductase activity [GO:0080007]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; S-nitrosoglutathione reductase activity [GO:0080007]	glutathione transferase activity [GO:0004364]
d3o6wa1_d4foeb3__1	Fungi	Metazoa	Ascomycota	Chordata	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d3o6wb2_d5wfnb1__1	Fungi	Metazoa	Ascomycota	Arthropoda	cell [GO:0005623]; ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	cell [GO:0005623]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	ATP binding [GO:0005524]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]	ATP binding [GO:0005524]
d3o73a__d3f6sg___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3o7ra__d3rnaa___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d3o7yb3_d1kxva1__1		Metazoa		Chordata		extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]		carbohydrate catabolic process [GO:0016052]		extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3o7yc3_d3lppb3__1		Metazoa		Chordata		apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]
d3o7za3_d2zxaa2__1				Thermotogae		lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]		fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]		lysosome [GO:0005764]		alpha-L-fucosidase activity [GO:0004560]
d3o7zb3_d3h55a2__1		Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]		carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d3o7zc3_d1eo5a3__1				Firmicutes		extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3o89a__d3wcte___1	Metazoa	Metazoa	Chordata	Annelida	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3o8aa__d4ab4b1__1			Apicomplexa	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; dihydroorotate dehydrogenase activity [GO:0004152]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; response to drug [GO:0042493]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; response to drug [GO:0042493]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]		dihydroorotate dehydrogenase activity [GO:0004152]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3o8jg__d6cscb___1		Metazoa	Proteobacteria	Chordata	mitochondrial matrix [GO:0005759]; 2-methylcitrate synthase activity [GO:0050440]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]; carbohydrate metabolic process [GO:0005975]; propionate metabolic process, methylcitrate cycle [GO:0019679]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]; carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; propionate metabolic process, methylcitrate cycle [GO:0019679]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2-methylcitrate synthase activity [GO:0050440]; citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]	citrate (Si)-synthase activity [GO:0004108]; citrate synthase activity [GO:0036440]
d3o8kb4_d1dfcb2__1		Metazoa		Chordata		actin cytoskeleton [GO:0015629]; cell cortex [GO:0005938]; cell projection membrane [GO:0031253]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; growth cone [GO:0030426]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; microspike [GO:0044393]; microvillus [GO:0005902]; podosome [GO:0002102]; ruffle [GO:0001726]; stress fiber [GO:0001725]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; drug binding [GO:0008144]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; cell motility [GO:0048870]; cell-cell junction assembly [GO:0007043]; cytokine-mediated signaling pathway [GO:0019221]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of cell polarity [GO:0007163]; microspike assembly [GO:0030035]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of podosome assembly [GO:0071803]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microvillus assembly [GO:0032534]		actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; cell-cell junction assembly [GO:0007043]; cell migration [GO:0016477]; cell motility [GO:0048870]; cytokine-mediated signaling pathway [GO:0019221]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of cell polarity [GO:0007163]; microspike assembly [GO:0030035]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of podosome assembly [GO:0071803]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microvillus assembly [GO:0032534]		actin cytoskeleton [GO:0015629]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection membrane [GO:0031253]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; growth cone [GO:0030426]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; microspike [GO:0044393]; microvillus [GO:0005902]; podosome [GO:0002102]; ruffle [GO:0001726]; stress fiber [GO:0001725]		actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; drug binding [GO:0008144]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]
d3o8xa1_d4p4ka1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d3o8xc1_d1q1ji1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d3o8xc2_d5wlge2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3o8xd1_d5ks9g1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d3o8yb2_d1ik3a1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nuclear envelope [GO:0005635]; nuclear envelope lumen [GO:0005641]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]; arachidonate 5-lipoxygenase activity [GO:0004051]; iron ion binding [GO:0005506]; cytokine-mediated signaling pathway [GO:0019221]; interleukin-18-mediated signaling pathway [GO:0035655]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; oxylipin biosynthetic process [GO:0031408]	cytokine-mediated signaling pathway [GO:0019221]; interleukin-18-mediated signaling pathway [GO:0035655]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; lipoxin biosynthetic process [GO:2001301]; lipoxygenase pathway [GO:0019372]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]	oxylipin biosynthetic process [GO:0031408]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nuclear envelope [GO:0005635]; nuclear envelope lumen [GO:0005641]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]	arachidonate 5-lipoxygenase activity [GO:0004051]; iron ion binding [GO:0005506]	metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d3o94b__d1nbad___1			Firmicutes	Actinobacteria	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	N-carbamoylsarcosine amidase activity [GO:0050127]; creatinine catabolic process [GO:0006602]		creatinine catabolic process [GO:0006602]			catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	N-carbamoylsarcosine amidase activity [GO:0050127]
d3o94c__d1yacb___1			Firmicutes	Proteobacteria	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; membrane [GO:0016020]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]				cytosol [GO:0005829]; membrane [GO:0016020]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; lyase activity [GO:0016829]
d3o95a2_d3ls2b___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]; formaldehyde catabolic process [GO:0046294]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	formaldehyde catabolic process [GO:0046294]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]
d3o95b2_d2wfme___1	Metazoa	Viridiplantae	Chordata	Streptophyta	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	polyneuridine-aldehyde esterase activity [GO:0050529]; alkaloid metabolic process [GO:0009820]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	alkaloid metabolic process [GO:0009820]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	polyneuridine-aldehyde esterase activity [GO:0050529]
d3o99a__d3oxvd___1					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3o99b__d2hpea___1					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3o9aa__d3th9b___1					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3o9aa__d4lbta___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]
d3o9ca__d4ye3a___1					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3o9ca__d5p8sa___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]
d3o9cb__d5hcta___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]
d3o9db__d1tw7a___1					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]
d3o9db__d5p6xa___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]
d3o9ea__d1e81e___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]
d3o9fb__d3nu6b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3o9ga__d2vkmc___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3o9gb__d5p2wa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3o9hb__d1hsia___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3o9ia__d5ozga___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3o9ib__d3b80b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3o9mb__d1cuia___1	Metazoa	Fungi	Chordata	Ascomycota	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]		blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	extracellular region [GO:0005576]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]	cutinase activity [GO:0050525]
d3o9na__d1vfob3__1	Viridiplantae		Streptophyta	Firmicutes	alpha-amylase inhibitor activity [GO:0015066]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; xylan catabolic process [GO:0045493]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			alpha-amylase inhibitor activity [GO:0015066]; hydrolase activity, acting on glycosyl bonds [GO:0016798]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d3o9pa__d4u4xa1__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]; tripeptide transport [GO:0042939]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	protein transport [GO:0015031]; tripeptide transport [GO:0042939]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	peptide transmembrane transporter activity [GO:1904680]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3o9va2_d1xqwa___1	Metazoa		Chordata	Euryarchaeota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	aminopeptidase activity [GO:0004177]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	aminopeptidase activity [GO:0004177]
d3o9vb2_d3fvrc___1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	acetylesterase activity [GO:0008126]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	acetylesterase activity [GO:0008126]
d3o9vc2_d5tnrd___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	hydrolase activity [GO:0016787]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	hydrolase activity [GO:0016787]
d3o9wa2_d1mi5e1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3o9wc1_d4llud2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3o9wd1_d1n4xm1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		antigen binding [GO:0003823]
d3o9wd1_d2fatl2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]			
d3o9wd2_d2ij0e___1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; toxin activity [GO:0090729]; pathogenesis [GO:0009405]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	pathogenesis [GO:0009405]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]		toxin activity [GO:0090729]
d3oa4a1_d1mpyd2__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; toluene catabolic process [GO:0042203]		toluene catabolic process [GO:0042203]			metal ion binding [GO:0046872]	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]
d3oamd__d3k8dd___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; 3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; magnesium ion binding [GO:0000287]; CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; lipopolysaccharide core region biosynthetic process [GO:0009244]	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0033468]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytosol [GO:0005829]	cytosol [GO:0005829]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]	3-deoxy-manno-octulosonate cytidylyltransferase activity [GO:0008690]; magnesium ion binding [GO:0000287]
d3oaul1_d1rpqd2__1		Metazoa		Chordata		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]		Fc-epsilon receptor signaling pathway [GO:0038095]		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		IgE binding [GO:0019863]
d3oayk2_d3cfkl1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3oayl1_d4grla2__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]		
d3oazl2_d2fedf2__1				Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3ob0k1_d2ak4l___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ob0k2_d1j89b2__1		Metazoa		Chordata		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]		Fc-epsilon receptor signaling pathway [GO:0038095]		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		IgE binding [GO:0019863]
d3ob0k2_d2x4ue1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3obpa1_d3o1ka___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]
d3obra1_d2ouja___1		Metazoa		Chordata	extracellular region [GO:0005576]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]; activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]	negative regulation of neurotransmitter secretion [GO:0046929]	activation of MAPK activity [GO:0000187]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; engulfment of apoptotic cell [GO:0043652]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002581]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of long-chain fatty acid import across plasma membrane [GO:0010748]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of sprouting angiogenesis [GO:1903671]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemotaxis [GO:0050921]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of macrophage activation [GO:0043032]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transforming growth factor beta1 production [GO:0032914]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of translation [GO:0045727]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of megakaryocyte differentiation [GO:0045652]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to magnesium ion [GO:0032026]; response to mechanical stimulus [GO:0009612]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to unfolded protein [GO:0006986]; sprouting angiogenesis [GO:0002040]	extracellular region [GO:0005576]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; sarcoplasmic reticulum [GO:0016529]; secretory granule [GO:0030141]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen V binding [GO:0070052]; extracellular matrix structural constituent [GO:0005201]; fibrinogen binding [GO:0070051]; fibroblast growth factor binding [GO:0017134]; fibronectin binding [GO:0001968]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; low-density lipoprotein particle binding [GO:0030169]; phosphatidylserine binding [GO:0001786]; proteoglycan binding [GO:0043394]; transforming growth factor beta binding [GO:0050431]
d3obra1_d4fqza2__1		Metazoa		Chordata	extracellular region [GO:0005576]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	negative regulation of neurotransmitter secretion [GO:0046929]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d3obsa1_d4yc1c___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]; autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]; autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]	calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]
d3obsa1_d5ojjf___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]; autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K6-linked ubiquitination [GO:0085020]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]	autophagosome maturation [GO:0097352]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; exosomal secretion [GO:1990182]; extracellular transport [GO:0006858]; intracellular transport of virus [GO:0075733]; keratinocyte differentiation [GO:0030216]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; endosome membrane [GO:0010008]; ESCRT I complex [GO:0000813]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; host cell [GO:0043657]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	calcium-dependent protein binding [GO:0048306]; DNA binding [GO:0003677]; nuclear receptor transcription coactivator activity [GO:0030374]; protein-containing complex binding [GO:0044877]; protein homodimerization activity [GO:0042803]; transcription corepressor activity [GO:0003714]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; virion binding [GO:0046790]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]
d3oc0a1_d2ajba1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3oc0a2_d3r3uc1__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	haloacetate dehalogenase activity [GO:0018785]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	haloacetate dehalogenase activity [GO:0018785]
d3oc3d1_d1vtle2__1	Fungi	Viridiplantae	Microsporidia	Streptophyta	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]	nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]		DNA-templated transcription, initiation [GO:0006352]; transcription by RNA polymerase II [GO:0006366]		nucleus [GO:0005634]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]	DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3occd__d5mx4a___1			Proteobacteria	Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	purine nucleoside metabolic process [GO:0042278]	purine nucleoside metabolic process [GO:0042278]			purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d3ocib2_d3oc3c1__1	Fungi	Fungi	Microsporidia	Microsporidia	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]; DNA-templated transcription, initiation [GO:0006352]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]	DNA-templated transcription, initiation [GO:0006352]				DNA binding [GO:0003677]; identical protein binding [GO:0042802]; translation initiation factor activity [GO:0003743]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]
d3ocpb__d3e5uc2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]	DNA binding [GO:0003677]
d3ocpb__d3h3ub1__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3od0a__d1ft9b2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d3od3a1_d1zdqb1__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3od3a3_d1uvwa5__1			Proteobacteria		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	
d3odoa1_d1lb1g1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; RNA binding [GO:0003723]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress fiber assembly [GO:0043149]; stress-activated protein kinase signaling cascade [GO:0031098]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; alpha-beta T cell lineage commitment [GO:0002363]; androgen receptor signaling pathway [GO:0030521]; angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; apical junction assembly [GO:0043297]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; beta selection [GO:0043366]; cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to chemokine [GO:1990869]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex cell migration [GO:0021795]; cleavage furrow formation [GO:0036089]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; ephrin receptor signaling pathway [GO:0048013]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; forebrain radial glial cell differentiation [GO:0021861]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; mitotic cleavage furrow formation [GO:1903673]; mitotic spindle assembly [GO:0090307]; negative chemotaxis [GO:0050919]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell size [GO:0045792]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intracellular steroid hormone receptor signaling pathway [GO:0033144]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; neuron projection morphogenesis [GO:0048812]; neutrophil degranulation [GO:0043312]; odontogenesis [GO:0042476]; ossification involved in bone maturation [GO:0043931]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell growth [GO:0030307]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokinesis [GO:0032467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipase activity [GO:0060193]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of T cell migration [GO:2000406]; positive regulation of translation [GO:0045727]; positive regulation of vascular smooth muscle contraction [GO:1904695]; protein deubiquitination [GO:0016579]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium ion transport [GO:0051924]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of dendrite development [GO:0050773]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of modification of postsynaptic actin cytoskeleton [GO:1905274]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of osteoblast proliferation [GO:0033688]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of transcription by RNA polymerase II [GO:0006357]; response to amino acid [GO:0043200]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]; skeletal muscle satellite cell migration [GO:1902766]; skeletal muscle tissue development [GO:0007519]; stress-activated protein kinase signaling cascade [GO:0031098]; stress fiber assembly [GO:0043149]; substantia nigra development [GO:0021762]; trabecula morphogenesis [GO:0061383]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	apical junction complex [GO:0043296]; axon [GO:0030424]; cell cortex [GO:0005938]; cell division site [GO:0032153]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; ficolin-1-rich granule membrane [GO:0101003]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; midbody [GO:0030496]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; ruffle membrane [GO:0032587]; secretory granule membrane [GO:0030667]; vesicle [GO:0031982]	G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; RNA binding [GO:0003723]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; Rho GDP-dissociation inhibitor binding [GO:0051022]
d3odoa2_d2coaa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; RNA binding [GO:0003723]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein kinase C binding [GO:0005080]; protein serine/threonine kinase activity [GO:0004674]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell death [GO:0008219]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; endothelial tube morphogenesis [GO:0061154]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; protein kinase D signaling [GO:0089700]; protein phosphorylation [GO:0006468]; sphingolipid biosynthetic process [GO:0030148]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell death [GO:0008219]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; endothelial tube morphogenesis [GO:0061154]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; protein kinase D signaling [GO:0089700]; protein phosphorylation [GO:0006468]; sphingolipid biosynthetic process [GO:0030148]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; RNA binding [GO:0003723]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein kinase C activity [GO:0004697]; protein kinase C binding [GO:0005080]; protein serine/threonine kinase activity [GO:0004674]
d3odob2_d2rvbb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; RNA binding [GO:0003723]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 2 complex [GO:0000111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of DNA damage [GO:0090734]; XPC complex [GO:0071942]; bubble DNA binding [GO:0000405]; damaged DNA binding [GO:0003684]; heteroduplex DNA loop binding [GO:0000404]; protein-containing complex binding [GO:0044877]; single-stranded DNA binding [GO:0003697]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; intra-S DNA damage checkpoint [GO:0031573]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to UV-B [GO:0010224]; UV-damage excision repair [GO:0070914]; UV-damage excision repair, DNA incision [GO:1990731]	G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]	DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; intra-S DNA damage checkpoint [GO:0031573]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to UV-B [GO:0010224]; UV-damage excision repair [GO:0070914]; UV-damage excision repair, DNA incision [GO:1990731]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleotide-excision repair complex [GO:0000109]; nucleotide-excision repair factor 2 complex [GO:0000111]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of DNA damage [GO:0090734]; XPC complex [GO:0071942]	G protein-coupled receptor binding [GO:0001664]; GTPase activator activity [GO:0005096]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; RNA binding [GO:0003723]	bubble DNA binding [GO:0000405]; damaged DNA binding [GO:0003684]; heteroduplex DNA loop binding [GO:0000404]; protein-containing complex binding [GO:0044877]; single-stranded DNA binding [GO:0003697]
d3odqa__d3a5aa___1	Metazoa	Metazoa	Chordata	Arthropoda	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3odqb__d1y0aa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3oe1a2_d5d7nc___1		Metazoa	Proteobacteria	Chordata	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3oe1a2_d6bd3a2__1		Fungi	Proteobacteria	Ascomycota	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]; acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		branched-chain amino acid biosynthetic process [GO:0009082]; isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]		acetolactate synthase complex [GO:0005948]; mitochondrion [GO:0005739]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; flavin adenine dinucleotide binding [GO:0050660]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3oe1b3_d5nd5a1__1		Viridiplantae	Proteobacteria	Chlorophyta	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	cytosol [GO:0005829]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]		pentose-phosphate shunt [GO:0006098]		cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	transketolase activity [GO:0004802]
d3oe1c2_d1o97d2__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]					magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]
d3oe1c3_d1ozhd3__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; butanediol metabolic process [GO:0034077]		butanediol metabolic process [GO:0034077]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	acetolactate synthase activity [GO:0003984]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3oe1c3_d2wvhv3__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]					magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d3oe1d1_d4qela3__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]		mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3oe4a__d3kpyb1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d3oe5a__d1zq9b___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity [GO:0052909]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]; positive regulation of rRNA processing [GO:2000234]; rRNA methylation [GO:0031167]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	positive regulation of rRNA processing [GO:2000234]; rRNA methylation [GO:0031167]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity [GO:0052909]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]
d3oe7e1_d5cdfe1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oe7e3_d1w0kf1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oe7f1_d4yxwf1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oe7f2_d2qe7e2__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oe7f3_d2qe7e3__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oe7m1_d5hkke1__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oe7o1_d2jizd1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oe7o3_d2jiza3__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oe7v1_d2qe7c1__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oe7x3_d2jj1f3__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oeca__d5g0ua___1			Actinobacteria	Actinobacteria	flavanone 4-reductase activity [GO:0047890]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]	flavanone 4-reductase activity [GO:0047890]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d3oeee1_d1efrd2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oeef1_d5ik2c1__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oeef3_d3tiva3__1	Fungi		Ascomycota	Euryarchaeota	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oeen3_d2jj1e3__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oeeo1_d3a5cf1__1	Fungi		Ascomycota	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]		hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oeev1_d1w0ja2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oeev2_d1cowc3__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oeev3_d5hkkk3__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oeex2_d1w0jf3__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oeex3_d3ssab3__1	Fungi		Ascomycota	Euryarchaeota	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oehd2_d1m7ha___1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	ATP synthesis coupled proton transport [GO:0015986]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]
d3oehf1_d2jiza1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oehf2_d3pv0a1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP synthesis coupled proton transport [GO:0015986]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3oehm2_d5xb3b___1	Fungi		Ascomycota	Aquificae	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	ATP synthesis coupled proton transport [GO:0015986]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]
d3oehn2_d2iy3a2__1	Fungi		Ascomycota	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	ATP synthesis coupled proton transport [GO:0015986]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	signal recognition particle [GO:0048500]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d3oeho3_d3a5cj4__1	Fungi		Ascomycota	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]		hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oehv1_d2qe7a1__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3oeid1_d4lsya___1			Actinobacteria	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	endoribonuclease activity [GO:0004521]; mRNA catabolic process [GO:0006402]; translational termination [GO:0006415]	regulation of transcription, DNA-templated [GO:0006355]	mRNA catabolic process [GO:0006402]; translational termination [GO:0006415]			DNA binding [GO:0003677]	endoribonuclease activity [GO:0004521]
d3oeih1_d2a6sa___1			Actinobacteria	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	endoribonuclease activity [GO:0004521]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; mRNA catabolic process [GO:0006402]; mRNA cleavage involved in gene silencing [GO:0098795]; negative regulation of translational initiation [GO:0045947]; RNA catabolic process [GO:0006401]; single-species biofilm formation [GO:0044010]	regulation of transcription, DNA-templated [GO:0006355]	mRNA catabolic process [GO:0006402]; mRNA cleavage involved in gene silencing [GO:0098795]; negative regulation of translational initiation [GO:0045947]; RNA catabolic process [GO:0006401]; single-species biofilm formation [GO:0044010]			DNA binding [GO:0003677]	endoribonuclease activity [GO:0004521]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]
d3oeik__d2a6qe1__1			Actinobacteria	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	endoribonuclease activity [GO:0004521]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; mRNA catabolic process [GO:0006402]; mRNA cleavage involved in gene silencing [GO:0098795]; negative regulation of translational initiation [GO:0045947]; RNA catabolic process [GO:0006401]; single-species biofilm formation [GO:0044010]	regulation of transcription, DNA-templated [GO:0006355]	mRNA catabolic process [GO:0006402]; mRNA cleavage involved in gene silencing [GO:0098795]; negative regulation of translational initiation [GO:0045947]; RNA catabolic process [GO:0006401]; single-species biofilm formation [GO:0044010]			DNA binding [GO:0003677]	endoribonuclease activity [GO:0004521]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]
d3oeil__d2a6rc___1			Actinobacteria	Proteobacteria	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	endoribonuclease activity [GO:0004521]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; mRNA catabolic process [GO:0006402]; mRNA cleavage involved in gene silencing [GO:0098795]; negative regulation of translational initiation [GO:0045947]; RNA catabolic process [GO:0006401]; single-species biofilm formation [GO:0044010]	regulation of transcription, DNA-templated [GO:0006355]	mRNA catabolic process [GO:0006402]; mRNA cleavage involved in gene silencing [GO:0098795]; negative regulation of translational initiation [GO:0045947]; RNA catabolic process [GO:0006401]; single-species biofilm formation [GO:0044010]			DNA binding [GO:0003677]	endoribonuclease activity [GO:0004521]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; ribosomal small subunit binding [GO:0043024]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]
d3oeu1__d4wl2a___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	hydrolase activity [GO:0016787]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	hydrolase activity [GO:0016787]
d3oeuc__d5cz5n___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oeud__d4qzwp___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oeuh__d4qlqj___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oeuh__d5l5ps___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oeuk__d1rypn___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oeuw__d4ltcu___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oeux__d1ya7m___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasome activator complex [GO:0008537]; proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis [GO:0006508]; regulation of proteasomal protein catabolic process [GO:0061136]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	proteasome activator complex [GO:0008537]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	
d3oeva__d1ofeb3__1	Fungi		Ascomycota	Cyanobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	3 iron, 4 sulfur cluster binding [GO:0051538]; glutamate synthase (ferredoxin) activity [GO:0016041]; metal ion binding [GO:0046872]; glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	3 iron, 4 sulfur cluster binding [GO:0051538]; glutamate synthase (ferredoxin) activity [GO:0016041]; metal ion binding [GO:0046872]
d3oeve__d5cz4q___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oevf__d5lexr___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oevg__d4wl3d___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	hydrolase activity [GO:0016787]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	hydrolase activity [GO:0016787]
d3oevg__d5cz6x___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oevh__d3d291___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oevm__d4quys___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oevr__d4cr2g___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oevr__d5lajs___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oevu__d5l5rz___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3of1a1_d4byyb1__1	Fungi		Ascomycota	Actinobacteria	cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; cGMP-mediated signaling [GO:0019934]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation [GO:0061406]; positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation [GO:0036278]; protein localization to bud neck [GO:0097271]; regulation of cytoplasmic mRNA processing body assembly [GO:0010603]	protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	cGMP-mediated signaling [GO:0019934]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation [GO:0061406]; positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation [GO:0036278]; protein localization to bud neck [GO:0097271]; regulation of cytoplasmic mRNA processing body assembly [GO:0010603]	regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	protein-DNA complex [GO:0032993]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3of3a__d3ozca___1		Metazoa	Proteobacteria	Chordata	purine-nucleoside phosphorylase activity [GO:0004731]; nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; phosphorylase activity [GO:0004645]; S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; interleukin-12-mediated signaling pathway [GO:0035722]; L-methionine salvage from methylthioadenosine [GO:0019509]; methylation [GO:0032259]; nucleobase-containing compound metabolic process [GO:0006139]; purine ribonucleoside salvage [GO:0006166]	nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	interleukin-12-mediated signaling pathway [GO:0035722]; L-methionine salvage from methylthioadenosine [GO:0019509]; methylation [GO:0032259]; nucleobase-containing compound metabolic process [GO:0006139]; purine ribonucleoside salvage [GO:0006166]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	purine-nucleoside phosphorylase activity [GO:0004731]	phosphorylase activity [GO:0004645]; S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]
d3of3c__d3occd___1			Proteobacteria	Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	purine nucleoside metabolic process [GO:0042278]			purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d3of3d__d4bmxb1__1			Proteobacteria	Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	cytosol [GO:0005829]; 6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]		cytosol [GO:0005829]	purine-nucleoside phosphorylase activity [GO:0004731]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d3of3g__d3qpba___1			Proteobacteria	Firmicutes	purine-nucleoside phosphorylase activity [GO:0004731]; nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]		cytoplasm [GO:0005737]	purine-nucleoside phosphorylase activity [GO:0004731]	uridine phosphorylase activity [GO:0004850]
d3of3i__d3occb___1			Proteobacteria	Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	purine nucleoside metabolic process [GO:0042278]			purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d3of3j__d1rxum___1			Proteobacteria	Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]		cytosol [GO:0005829]	purine-nucleoside phosphorylase activity [GO:0004731]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]
d3of3l__d3uaza___1			Proteobacteria	Firmicutes	purine-nucleoside phosphorylase activity [GO:0004731]; nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	purine nucleoside metabolic process [GO:0042278]			purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d3of6a1_d1fq9c2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; negative regulation of thymocyte apoptotic process [GO:0070244]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	negative regulation of thymocyte apoptotic process [GO:0070244]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	integral component of membrane [GO:0016021]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]
d3of6a2_d1u8ha1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; negative regulation of thymocyte apoptotic process [GO:0070244]		negative regulation of thymocyte apoptotic process [GO:0070244]		integral component of membrane [GO:0016021]			
d3of6b1_d4tvpl1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; negative regulation of thymocyte apoptotic process [GO:0070244]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	negative regulation of thymocyte apoptotic process [GO:0070244]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d3of9a__d1csb.2__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; histone binding [GO:0042393]; proteoglycan binding [GO:0043394]; serpin family protein binding [GO:0097655]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; macrophage apoptotic process [GO:0071888]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; macrophage apoptotic process [GO:0071888]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; perinuclear region of cytoplasm [GO:0048471]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; histone binding [GO:0042393]; proteoglycan binding [GO:0043394]; serpin family protein binding [GO:0097655]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]
d3ofma__d5usza___1	Metazoa	Metazoa	Chordata	Chordata	acrosomal vesicle [GO:0001669]; chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cerebral cortex development [GO:0021987]; liver regeneration [GO:0097421]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein folding [GO:0006457]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]	caveola [GO:0005901]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome lumen [GO:0031904]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; acetylcholine receptor binding [GO:0033130]; ATP binding [GO:0005524]; growth hormone receptor binding [GO:0005131]; heme binding [GO:0020037]; histone binding [GO:0042393]; histone kinase activity (H3-Y41 specific) [GO:0035401]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; interleukin-12 receptor binding [GO:0005143]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; type 1 angiotensin receptor binding [GO:0031702]; actin filament polymerization [GO:0030041]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activation of Janus kinase activity [GO:0042976]; activation of MAPKK activity [GO:0000186]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; axon regeneration [GO:0031103]; blood coagulation [GO:0007596]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; enzyme linked receptor protein signaling pathway [GO:0007167]; erythrocyte differentiation [GO:0030218]; extrinsic apoptotic signaling pathway [GO:0097191]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; histone H3-Y41 phosphorylation [GO:0035409]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; mammary gland epithelium development [GO:0061180]; MAPK cascade [GO:0000165]; mesoderm development [GO:0007498]; microglial cell activation [GO:0001774]; mineralocorticoid receptor signaling pathway [GO:0031959]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of DNA binding [GO:0043392]; negative regulation of heart contraction [GO:0045822]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell activation [GO:0050867]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial cell apoptotic process [GO:1904037]; positive regulation of growth factor dependent skeletal muscle satellite cell proliferation [GO:1902728]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; positive regulation of inflammatory response [GO:0050729]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; postsynapse to nucleus signaling pathway [GO:0099527]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of inflammatory response [GO:0050727]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; response to antibiotic [GO:0046677]; response to hydroperoxide [GO:0033194]; response to interleukin-12 [GO:0070671]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; tyrosine phosphorylation of STAT protein [GO:0007260]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cerebral cortex development [GO:0021987]; liver regeneration [GO:0097421]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein folding [GO:0006457]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]	actin filament polymerization [GO:0030041]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activation of Janus kinase activity [GO:0042976]; activation of MAPKK activity [GO:0000186]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; axon regeneration [GO:0031103]; blood coagulation [GO:0007596]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; enzyme linked receptor protein signaling pathway [GO:0007167]; erythrocyte differentiation [GO:0030218]; extrinsic apoptotic signaling pathway [GO:0097191]; G protein-coupled receptor signaling pathway [GO:0007186]; growth hormone receptor signaling pathway [GO:0060396]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; histone H3-Y41 phosphorylation [GO:0035409]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-23-mediated signaling pathway [GO:0038155]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; mammary gland epithelium development [GO:0061180]; MAPK cascade [GO:0000165]; mesoderm development [GO:0007498]; microglial cell activation [GO:0001774]; mineralocorticoid receptor signaling pathway [GO:0031959]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA binding [GO:0043392]; negative regulation of heart contraction [GO:0045822]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell activation [GO:0050867]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial cell apoptotic process [GO:1904037]; positive regulation of growth factor dependent skeletal muscle satellite cell proliferation [GO:1902728]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; positive regulation of inflammatory response [GO:0050729]; positive regulation of insulin secretion [GO:0032024]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; postsynapse to nucleus signaling pathway [GO:0099527]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of inflammatory response [GO:0050727]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; response to antibiotic [GO:0046677]; response to hydroperoxide [GO:0033194]; response to interleukin-12 [GO:0070671]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; tyrosine phosphorylation of STAT protein [GO:0007260]	acrosomal vesicle [GO:0001669]; chromatin [GO:0000785]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	caveola [GO:0005901]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; endosome lumen [GO:0031904]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	ATP binding [GO:0005524]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]	acetylcholine receptor binding [GO:0033130]; ATP binding [GO:0005524]; growth hormone receptor binding [GO:0005131]; heme binding [GO:0020037]; histone binding [GO:0042393]; histone kinase activity (H3-Y41 specific) [GO:0035401]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; interleukin-12 receptor binding [GO:0005143]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; type 1 angiotensin receptor binding [GO:0031702]
d3og2a1_d5gqeb1__1	Fungi		Ascomycota	Actinobacteria	beta-galactosidase activity [GO:0004565]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]			beta-galactosidase activity [GO:0004565]	endo-1,4-beta-xylanase activity [GO:0031176]
d3og2a4_d4omdb2__1	Fungi	Metazoa	Ascomycota	Chordata	beta-galactosidase activity [GO:0004565]; carbohydrate metabolic process [GO:0005975]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	carbohydrate metabolic process [GO:0005975]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	beta-galactosidase activity [GO:0004565]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d3og9a__d5tnnd___1			Firmicutes	Proteobacteria	hydrolase activity [GO:0016787]	hydrolase activity [GO:0016787]					hydrolase activity [GO:0016787]	hydrolase activity [GO:0016787]
d3ogga1_d1lgc.3__1		Viridiplantae		Streptophyta	extracellular region [GO:0005576]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]		ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3ogjd__d2h6ba2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]	DNA binding [GO:0003677]
d3ognb__d1qwva___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	pheromone binding [GO:0005550]; response to pheromone [GO:0019236]		response to pheromone [GO:0019236]			odorant binding [GO:0005549]	pheromone binding [GO:0005550]
d3ognb__d3n7hb___1	Metazoa	Metazoa	Arthropoda	Arthropoda	odorant binding [GO:0005549]	odorant binding [GO:0005549]					odorant binding [GO:0005549]	odorant binding [GO:0005549]
d3ogof__d4wfgd2__1	Metazoa	Metazoa	Cnidaria	Chordata	bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]; identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]; cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]	bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]	cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]		identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]
d3ogoh1_d1mjuh1__1	Metazoa		Cnidaria		bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]		bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]					
d3ogoh1_d5n4jl1__1	Metazoa		Cnidaria		bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]		bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091]; protein-chromophore linkage [GO:0018298]					
d3ogpa__d1hvia___1					aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ogqa__d1xn3c___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3ogqb__d3nu9b___1					aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ogsa1_d2z1sa___1	Fungi		Ascomycota	Firmicutes	beta-galactosidase activity [GO:0004565]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]			beta-galactosidase activity [GO:0004565]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3ogsa5_d1gwma1__1	Fungi	Fungi	Ascomycota	Chytridiomycota	beta-galactosidase activity [GO:0004565]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				beta-galactosidase activity [GO:0004565]	
d3ogva1_d1jyyb5__1	Fungi		Ascomycota		beta-galactosidase activity [GO:0004565]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				beta-galactosidase activity [GO:0004565]	
d3ogva5_d3t09b1__1	Fungi		Ascomycota	Proteobacteria	beta-galactosidase activity [GO:0004565]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-galactosidase activity [GO:0004565]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3ogxd__d2xz4a___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; peptidoglycan receptor activity [GO:0016019]; signaling receptor binding [GO:0005102]; zinc ion binding [GO:0008270]; antibacterial humoral response [GO:0019731]; antimicrobial humoral response [GO:0019730]; defense response to Gram-positive bacterium [GO:0050830]; defense response to other organism [GO:0098542]; determination of adult lifespan [GO:0008340]; innate immune response [GO:0045087]; negative regulation of immune response [GO:0050777]; negative regulation of JNK cascade [GO:0046329]; negative regulation of natural killer cell differentiation involved in immune response [GO:0032827]; negative regulation of peptidoglycan recognition protein signaling pathway [GO:0061060]; peptidoglycan catabolic process [GO:0009253]; response to bacterium [GO:0009617]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	antibacterial humoral response [GO:0019731]; antimicrobial humoral response [GO:0019730]; defense response to Gram-positive bacterium [GO:0050830]; defense response to other organism [GO:0098542]; determination of adult lifespan [GO:0008340]; innate immune response [GO:0045087]; negative regulation of immune response [GO:0050777]; negative regulation of JNK cascade [GO:0046329]; negative regulation of natural killer cell differentiation involved in immune response [GO:0032827]; negative regulation of peptidoglycan recognition protein signaling pathway [GO:0061060]; peptidoglycan catabolic process [GO:0009253]; response to bacterium [GO:0009617]	extracellular region [GO:0005576]	extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; peptidoglycan receptor activity [GO:0016019]; signaling receptor binding [GO:0005102]; zinc ion binding [GO:0008270]
d3ohba2_d2r8ha1__1	Fungi		Ascomycota	Crenarchaeota	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]; DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	chromosome segregation [GO:0007059]; DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; replication fork [GO:0005657]; site of double-strand break [GO:0035861]	cytoplasm [GO:0005737]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-directed DNA polymerase activity [GO:0003887]; magnesium ion binding [GO:0000287]
d3ohua1_d1qdwh___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; import into nucleus [GO:0051170]; primary adaptive immune response involving T cells and B cells [GO:0090721]; regulation of transcription, DNA-templated [GO:0006355]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	import into nucleus [GO:0051170]; primary adaptive immune response involving T cells and B cells [GO:0090721]; regulation of transcription, DNA-templated [GO:0006355]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]
d3ohuf__d1qdvd___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; import into nucleus [GO:0051170]; primary adaptive immune response involving T cells and B cells [GO:0090721]; regulation of transcription, DNA-templated [GO:0006355]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	import into nucleus [GO:0051170]; primary adaptive immune response involving T cells and B cells [GO:0090721]; regulation of transcription, DNA-templated [GO:0006355]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]
d3ohva1_d5a6rc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; import into nucleus [GO:0051170]; primary adaptive immune response involving T cells and B cells [GO:0090721]; regulation of transcription, DNA-templated [GO:0006355]	Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; cullin family protein binding [GO:0097602]; identical protein binding [GO:0042802]; cell projection organization [GO:0030030]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; positive regulation of cilium assembly [GO:0045724]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]	import into nucleus [GO:0051170]; primary adaptive immune response involving T cells and B cells [GO:0090721]; regulation of transcription, DNA-templated [GO:0006355]	cell projection organization [GO:0030030]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; positive regulation of cilium assembly [GO:0045724]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]	cullin family protein binding [GO:0097602]; identical protein binding [GO:0042802]
d3oiaa__d2fdya___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d3oifa__d2bgma___1		Viridiplantae	Firmicutes	Streptophyta	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; cellular response to cold [GO:0070417]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	(-)-secoisolariciresinol dehydrogenase activity [GO:0102911]; nucleotide binding [GO:0000166]; lignan biosynthetic process [GO:0009807]; protein homotetramerization [GO:0051289]	cellular response to cold [GO:0070417]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	lignan biosynthetic process [GO:0009807]; protein homotetramerization [GO:0051289]			enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]	(-)-secoisolariciresinol dehydrogenase activity [GO:0102911]; nucleotide binding [GO:0000166]
d3oiha__d3wlkx1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	alpha-amylase inhibitor activity [GO:0015066]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			alpha-amylase inhibitor activity [GO:0015066]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3oj1a__d1nz4a___1	Metazoa	Metazoa	Annelida	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3oj2a__d4qo3b1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3oj2d1_d2pyea1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	
d3oj3c__d4waab1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d3oj3d__d5chfe2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3oj3e__d5chwj1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3oj3h__d3waoc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d3oj5b__d2jd7c___1			Actinobacteria	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]
d3oj5f__d2xjmj___1			Actinobacteria	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d3oj5g__d4xgsa1__1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular response to DNA damage stimulus [GO:0006974]; cellular response to iron ion [GO:0071281]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; response to oxidative stress [GO:0006979]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3oj5h__d3rbce___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3oj5i__d1z6om1__1		Metazoa	Actinobacteria	Arthropoda	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3oj5k__d4toch___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3oj5k__d5ww4b___1			Actinobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3oj5l__d5tdvd___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	toluene catabolic process [GO:0042203]	cell [GO:0005623]		ferric iron binding [GO:0008199]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d3oj5o__d1mfrk___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3oj5r__d1oq7a___1		Viridiplantae	Actinobacteria	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]	chloroplast [GO:0009507]	ferric iron binding [GO:0008199]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d3oj5s__d2bk6c___1			Actinobacteria	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3oj5t__d3bvfe1__1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d3oj5u__d4p18a___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3oj5x__d2jd72___1			Actinobacteria	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]
d3oj8a__d1ockb___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]	amidase activity [GO:0004040]	fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]		acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]	amidase activity [GO:0004040]
d3ojba1_d4ayua___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d3ojbd1_d3zvxa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]		carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3ojda2_d1k4db2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ojfa1_d3i3oc___1			Firmicutes	Firmicutes	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]				enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3ojfb1_d5je8d1__1			Firmicutes	Firmicutes	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]				enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3ojfd1_d4c7ka___1		Metazoa	Firmicutes	Chordata	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d3ojja2_d4ghhc1__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3ojjd2_d1lkda2__1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]		aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]
d3ojkc1_d3rmuc1__1		Metazoa	Actinobacteria	Chordata	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	mitochondrial matrix [GO:0005759]; metal ion binding [GO:0046872]; methylmalonyl-CoA epimerase activity [GO:0004493]; L-methylmalonyl-CoA metabolic process [GO:0046491]; short-chain fatty acid catabolic process [GO:0019626]		L-methylmalonyl-CoA metabolic process [GO:0046491]; short-chain fatty acid catabolic process [GO:0019626]		mitochondrial matrix [GO:0005759]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; methylmalonyl-CoA epimerase activity [GO:0004493]
d3ojkd1_d1kmya2__1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]		aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]
d3ojkd2_d2zi8b2__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity [GO:0047071]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; aromatic compound catabolic process [GO:0019439]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; response to cholesterol [GO:0070723]		aromatic compound catabolic process [GO:0019439]; cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; response to cholesterol [GO:0070723]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity [GO:0047071]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]
d3ojmb1_d1tjil1__1	Metazoa		Chordata		cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	structural molecule activity [GO:0005198]
d3ojmb2_d4bsva2__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ojna1_d1kwcb1__1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]		aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]
d3ojnc1_d4z6zc2__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3ojnc2_d1q0ob1__1			Actinobacteria	Actinobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3ojnd2_d1knda2__1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]		aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]
d3ojpa__d1f6re___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]
d3ojta1_d3hpvb2__1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	catechol 2,3-dioxygenase activity [GO:0018577]; ferrous iron binding [GO:0008198]
d3ojvc1_d4lf3d1__1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; G protein-coupled peptide receptor activity [GO:0008528]; glucagon receptor activity [GO:0004967]; guanyl-nucleotide exchange factor activity [GO:0005085]; peptide hormone binding [GO:0017046]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glucagon stimulus [GO:0071377]; exocytosis [GO:0006887]; G protein-coupled receptor signaling pathway [GO:0007186]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; regulation of blood pressure [GO:0008217]; regulation of glycogen metabolic process [GO:0070873]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; cellular response to glucagon stimulus [GO:0071377]; exocytosis [GO:0006887]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; G protein-coupled receptor signaling pathway [GO:0007186]; hormone-mediated signaling pathway [GO:0009755]; regulation of blood pressure [GO:0008217]; regulation of glycogen metabolic process [GO:0070873]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	glucagon receptor activity [GO:0004967]; G protein-coupled peptide receptor activity [GO:0008528]; guanyl-nucleotide exchange factor activity [GO:0005085]; peptide hormone binding [GO:0017046]
d3ojvc2_d1miel2__1	Metazoa		Chordata		cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]		activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]		cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]		fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	
d3ojvd2_d3owem___1	Metazoa		Chordata	Firmicutes	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	pathogenesis [GO:0009405]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	
d3ojwa3_d1gjra2__1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	phycobilisome [GO:0030089]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d3ojwa3_d5fa6b3__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d3ojxa3_d2vyqa2__1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	phycobilisome [GO:0030089]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d3okda1_d1tzib1__1		Metazoa		Chordata		cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]
d3okja__d4z1ls___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3okjj__d5l65c___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3okjp__d5jhsn___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3okjw__d2bpjb1__1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	
d3okjx__d5thoi___1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	modification-dependent protein catabolic process [GO:0019941]; pathogenesis [GO:0009405]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cell wall [GO:0005618]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; proteasome core complex, alpha-subunit complex [GO:0019773]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	threonine-type endopeptidase activity [GO:0004298]
d3okka1_d2ddql1__1		Metazoa		Chordata								
d3okla1_d3kpre1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3okma1_d1uz6h1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3okna1_d5u4lb___1		Viridiplantae		Streptophyta		endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]		endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3okoa1_d2uyla2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3okoa2_d1cdha2__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3ol5a__d3ebsc___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d3olda1_d1wzma3__1	Metazoa		Chordata	Firmicutes	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d3olda1_d2gk1l1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d3olea1_d5i2ub___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	
d3olga2_d3lxca2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d3olga2_d3o7za3__1	Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]	
d3olkc__d3hmaa___1												
d3olwb__d5iulc1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]; protein dimerization activity [GO:0046983]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		cytosol [GO:0005829]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]; protein dimerization activity [GO:0046983]
d3olxa__d1dcma___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3olxb__d4nicb___1			Proteobacteria		cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	
d3olya__d5lwkb___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	DNA-binding transcription factor activity [GO:0003700]; phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	DNA-binding transcription factor activity [GO:0003700]
d3olyb__d4l85c1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription factor activity [GO:0003700]; phosphorelay response regulator activity [GO:0000156]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3om3b2_d1sf3a___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3om3d2_d2vmja1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]		copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3om4b__d1y7bd2__1			Firmicutes	Firmicutes	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate utilization [GO:0009758]	carbohydrate metabolic process [GO:0005975]			levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3om4c__d3byna___1			Firmicutes	Firmicutes	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]	extracellular region [GO:0005576]; levansucrase activity [GO:0050053]; carbohydrate utilization [GO:0009758]	carbohydrate utilization [GO:0009758]	carbohydrate utilization [GO:0009758]		extracellular region [GO:0005576]	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]	levansucrase activity [GO:0050053]
d3om4c__d5aydb___1			Firmicutes	Firmicutes	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]	transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate utilization [GO:0009758]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]			levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]	transferase activity, transferring glycosyl groups [GO:0016757]
d3om5b__d5ayda___1			Firmicutes	Firmicutes	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]	transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]	carbohydrate utilization [GO:0009758]	carbohydrate metabolic process [GO:0005975]; cell wall organization [GO:0071555]			levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]	transferase activity, transferring glycosyl groups [GO:0016757]
d3om5c__d5joxb1__1			Firmicutes	Bacteroidetes	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]	periplasmic space [GO:0042597]; alpha-L-arabinofuranosidase activity [GO:0046556]; symbiotic process benefiting host [GO:0085030]; xyloglucan catabolic process [GO:2000899]	carbohydrate utilization [GO:0009758]	symbiotic process benefiting host [GO:0085030]; xyloglucan catabolic process [GO:2000899]		periplasmic space [GO:0042597]	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]	alpha-L-arabinofuranosidase activity [GO:0046556]
d3om5d__d3d5za___1			Firmicutes	Firmicutes	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]	cytoplasm [GO:0005737]; arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]; arabinan catabolic process [GO:0031222]	carbohydrate utilization [GO:0009758]	arabinan catabolic process [GO:0031222]		cytoplasm [GO:0005737]	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]	arabinan endo-1,5-alpha-L-arabinosidase activity [GO:0046558]; metal ion binding [GO:0046872]
d3om6b__d4udkd___1			Firmicutes		levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]		carbohydrate utilization [GO:0009758]				levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]	
d3om7a__d2exhc2__1			Firmicutes	Firmicutes	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate utilization [GO:0009758]	carbohydrate metabolic process [GO:0005975]			levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3om7a__d3om4b___1			Firmicutes	Firmicutes	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]	carbohydrate utilization [GO:0009758]	carbohydrate utilization [GO:0009758]			levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]
d3om7c__d1w2tb2__1			Firmicutes	Thermotogae	levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]	carbohydrate utilization [GO:0009758]	carbohydrate metabolic process [GO:0005975]			levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]	beta-fructofuranosidase activity [GO:0004564]
d3om7d__d4udgb___1			Firmicutes		levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]; carbohydrate utilization [GO:0009758]		carbohydrate utilization [GO:0009758]				levansucrase activity [GO:0050053]; metal ion binding [GO:0046872]	
d3om9a1_d4imra1__1			Apicomplexa	Proteobacteria	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	nucleotide binding [GO:0000166]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]				L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d3om9b2_d3pqfc2__1			Apicomplexa	Firmicutes	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	L-lactate dehydrogenase activity [GO:0004459]
d3omab2_d1nina___1			Proteobacteria	Cyanobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	thylakoid membrane [GO:0042651]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3omad2_d2tsba___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3omnd2_d3uaaa1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d3onca__d1ieia___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d3onvc__d3nbqc___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uridine phosphorylase activity [GO:0004850]; cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	uridine phosphorylase activity [GO:0004850]
d3oo4a__d4jacb___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d3oo5b__d1jzmb___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3ooba2_d5b8ic___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	phosphoprotein phosphatase activity [GO:0004721]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]		beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	phosphoprotein phosphatase activity [GO:0004721]
d3oohb__d4ecee___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]
d3oohd__d3e9zc___1		Metazoa	Proteobacteria	Platyhelminthes	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]; membrane [GO:0016020]		identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d3oohg__d4rj2b___1			Proteobacteria		cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]		cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]		cytosol [GO:0005829]; membrane [GO:0016020]		identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	
d3oohk__d5loka___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytosol [GO:0005829]; membrane [GO:0016020]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]
d3oohm__d5mx6e___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	purine nucleoside metabolic process [GO:0042278]	cytosol [GO:0005829]; membrane [GO:0016020]		identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d3ooho__d3mb8b1__1			Proteobacteria	Apicomplexa	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]; membrane [GO:0016020]		identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d3ooho__d4ttad___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]
d3oojb2_d2x3yc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytoplasm [GO:0005737]; carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]; capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	capsule polysaccharide biosynthetic process [GO:0045227]; D-glycero-D-manno-heptose 7-phosphate biosynthetic process [GO:2001061]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	carbohydrate derivative binding [GO:0097367]; D-sedoheptulose 7-phosphate isomerase activity [GO:0008968]; zinc ion binding [GO:0008270]
d3oojc2_d1tzbb___1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]; carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]		carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	carbohydrate derivative binding [GO:0097367]; glucose-6-phosphate isomerase activity [GO:0004347]; mannose-6-phosphate isomerase activity [GO:0004476]
d3ooje1_d5l69e___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3oota__d3bvba___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ootb__d3qiha___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3opkb__d1v6ha___1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; response to metal ion [GO:0010038]	response to metal ion [GO:0010038]	response to metal ion [GO:0010038]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	copper ion binding [GO:0005507]	
d3opkc1_d4yb6d2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; response to metal ion [GO:0010038]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	response to metal ion [GO:0010038]	histidine biosynthetic process [GO:0000105]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	copper ion binding [GO:0005507]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d3opmc2_d1ticb___1	Metazoa	Fungi	Chordata	Mucoromycota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d3opmd2_d1e5ta2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d3opvc__d3eufa___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; uridine phosphorylase activity [GO:0004850]; cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	uridine phosphorylase activity [GO:0004850]
d3opvf__d1u1ef___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]
d3opvf__d2qtga___1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; membrane [GO:0016020]; identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]; cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cellular response to DNA damage stimulus [GO:0006974]; purine nucleoside catabolic process [GO:0006152]; purine nucleoside interconversion [GO:0019686]	L-methionine salvage from methylthioadenosine [GO:0019509]; nucleoside metabolic process [GO:0009116]; phloem or xylem histogenesis [GO:0010087]; reproduction [GO:0000003]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; purine-nucleoside phosphorylase activity [GO:0004731]	adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d3oq1b1_d2gr9c1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]; cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cellular amino acid biosynthetic process [GO:0008652]; cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	identical protein binding [GO:0042802]; pyrroline-5-carboxylate reductase activity [GO:0004735]
d3oq1d1_d3rbxc1__1	Metazoa		Chordata	Euryarchaeota	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	potassium ion transport [GO:0006813]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3oq3a__d1higa___1		Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular respiration [GO:1901857]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of iron ion import across plasma membrane [GO:1904440]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vitamin D biosynthetic process [GO:0060557]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein ADP-ribosylation [GO:0010835]; regulation of regulatory T cell differentiation [GO:0045589]; response to virus [GO:0009615]		adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; humoral immune response [GO:0006959]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-12-mediated signaling pathway [GO:0035722]; microglial cell activation [GO:0001774]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroinflammatory response [GO:0150076]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of autophagy [GO:0010508]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular respiration [GO:1901857]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of core promoter binding [GO:1904798]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity [GO:0060550]; positive regulation of fructose 1,6-bisphosphate metabolic process [GO:0060552]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of iron ion import across plasma membrane [GO:1904440]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000309]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vitamin D biosynthetic process [GO:0060557]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of growth [GO:0040008]; regulation of insulin secretion [GO:0050796]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein ADP-ribosylation [GO:0010835]; regulation of regulatory T cell differentiation [GO:0045589]; response to virus [GO:0009615]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; interferon-gamma receptor binding [GO:0005133]
d3oq7a__d2f8gb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3oqfb__d4phvb___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3oqfb__d5p5ya___1	Metazoa	Fungi	Chordata	Ascomycota	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]
d3oqka__d5p6aa___1	Metazoa	Fungi	Chordata	Ascomycota	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]
d3oqtb__d2vxaj___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]			extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d3oqtc__d2v18l___1			Actinobacteria	Deinococcus-Thermus	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]			extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d3oqtc__d2vxab___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]			extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d3oqtf__d2degd___1			Actinobacteria	Deinococcus-Thermus	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]			extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d3oqtf__d2yj0c___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d3oqtg__d2dehd___1			Actinobacteria	Deinococcus-Thermus	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]				extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	
d3oqtj__d2yj0e___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d3oqtk__d2vxag___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]			extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d3oqtk__d4b2ha___1			Actinobacteria	Euryarchaeota	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]			extracellular region [GO:0005576]	cytosol [GO:0005829]	nucleotide binding [GO:0000166]	
d3oqtl__d2yj0a___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d3oqtm__d2ux9b___1			Actinobacteria	Deinococcus-Thermus	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]			extracellular region [GO:0005576]		nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d3oqtp__d2yj0f___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]	extracellular region [GO:0005576]; nucleotide binding [GO:0000166]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]
d3or1f__d2xsjc___1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]					4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d3or2f__d1yx3a___1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]	transferase activity [GO:0016740]	sulfur compound metabolic process [GO:0006790]				4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]	transferase activity [GO:0016740]
d3or6a1_d4crpa1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome membrane [GO:0055038]; ATP binding [GO:0005524]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; nerve growth factor binding [GO:0048406]; nerve growth factor receptor activity [GO:0010465]; neurotrophin binding [GO:0043121]; neurotrophin p75 receptor binding [GO:0005166]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of MAPKK activity [GO:0000186]; aging [GO:0007568]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; B cell differentiation [GO:0030183]; behavioral response to formalin induced pain [GO:0061368]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to nicotine [GO:0071316]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; learning or memory [GO:0007611]; mechanoreceptor differentiation [GO:0042490]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; neurotrophin TRK receptor signaling pathway [GO:0048011]; olfactory nerve development [GO:0021553]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; programmed cell death involved in cell development [GO:0010623]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to hydrostatic pressure [GO:0051599]; response to nutrient levels [GO:0031667]; response to radiation [GO:0009314]; Sertoli cell development [GO:0060009]; sympathetic nervous system development [GO:0048485]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		activation of MAPKK activity [GO:0000186]; aging [GO:0007568]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; B cell differentiation [GO:0030183]; behavioral response to formalin induced pain [GO:0061368]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to nicotine [GO:0071316]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; learning or memory [GO:0007611]; mechanoreceptor differentiation [GO:0042490]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; neuron development [GO:0048666]; neuron projection development [GO:0031175]; neurotrophin TRK receptor signaling pathway [GO:0048011]; olfactory nerve development [GO:0021553]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; programmed cell death involved in cell development [GO:0010623]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; response to axon injury [GO:0048678]; response to electrical stimulus [GO:0051602]; response to hydrostatic pressure [GO:0051599]; response to nutrient levels [GO:0031667]; response to radiation [GO:0009314]; Sertoli cell development [GO:0060009]; sympathetic nervous system development [GO:0048485]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	voltage-gated potassium channel complex [GO:0008076]	axon [GO:0030424]; cell surface [GO:0009986]; dendrite [GO:0030425]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome membrane [GO:0055038]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	ATP binding [GO:0005524]; GPI-linked ephrin receptor activity [GO:0005004]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; nerve growth factor binding [GO:0048406]; nerve growth factor receptor activity [GO:0010465]; neurotrophin binding [GO:0043121]; neurotrophin p75 receptor binding [GO:0005166]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3or6b2_d4at6d2__1			Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	
d3ordb__d2uuln___1	Metazoa		Annelida		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	
d3orfc__d5en4a___1		Metazoa		Chordata	cytoplasm [GO:0005737]; phagocytic vesicle [GO:0045335]; 6,7-dihydropteridine reductase activity [GO:0004155]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]; L-phenylalanine catabolic process [GO:0006559]; response to oxidative stress [GO:0006979]; tetrahydrobiopterin biosynthetic process [GO:0006729]	cytosol [GO:0005829]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	L-phenylalanine catabolic process [GO:0006559]; response to oxidative stress [GO:0006979]; tetrahydrobiopterin biosynthetic process [GO:0006729]	estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	cytoplasm [GO:0005737]; phagocytic vesicle [GO:0045335]	cytosol [GO:0005829]	6,7-dihydropteridine reductase activity [GO:0004155]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; protein homodimerization activity [GO:0042803]	estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]
d3orhd__d1p1bc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; guanidinoacetate N-methyltransferase activity [GO:0030731]; methyltransferase activity [GO:0008168]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; animal organ morphogenesis [GO:0009887]; creatine biosynthetic process [GO:0006601]; creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]	animal organ morphogenesis [GO:0009887]; creatine biosynthetic process [GO:0006601]; creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]	creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	guanidinoacetate N-methyltransferase activity [GO:0030731]; methyltransferase activity [GO:0008168]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	guanidinoacetate N-methyltransferase activity [GO:0030731]; protein homodimerization activity [GO:0042803]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d3orhd__d3hcea___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; guanidinoacetate N-methyltransferase activity [GO:0030731]; methyltransferase activity [GO:0008168]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; animal organ morphogenesis [GO:0009887]; creatine biosynthetic process [GO:0006601]; creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; phenylethanolamine N-methyltransferase activity [GO:0004603]; catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	animal organ morphogenesis [GO:0009887]; creatine biosynthetic process [GO:0006601]; creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]	catecholamine biosynthetic process [GO:0042423]; epinephrine biosynthetic process [GO:0042418]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	guanidinoacetate N-methyltransferase activity [GO:0030731]; methyltransferase activity [GO:0008168]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]	phenylethanolamine N-methyltransferase activity [GO:0004603]
d3orse1_d2nsha___1			Firmicutes	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; identical protein binding [GO:0042802]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]		cytosol [GO:0005829]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; identical protein binding [GO:0042802]
d3orsg1_d1u11b___1			Firmicutes	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d3orya1_d1v8pc1__1			Crenarchaeota	Crenarchaeota	5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]	exonuclease activity [GO:0004527]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]	DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]				5'-3' exonuclease activity [GO:0008409]; 5'-flap endonuclease activity [GO:0017108]; DNA binding [GO:0003677]; magnesium ion binding [GO:0000287]	exonuclease activity [GO:0004527]; magnesium ion binding [GO:0000287]; ribonuclease activity [GO:0004540]
d3os5a2_d3hnab___1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; histone-lysine N-methyltransferase activity [GO:0018024]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; heterochromatin organization [GO:0070828]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of histone H3-K9 methylation [GO:0051570]; response to ethanol [GO:0045471]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; C2H2 zinc finger domain binding [GO:0070742]; histone methyltransferase activity (H3-K27 specific) [GO:0046976]; histone methyltransferase activity (H3-K9 specific) [GO:0046974]; histone-lysine N-methyltransferase activity [GO:0018024]; methyltransferase activity [GO:0008168]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]; zinc ion binding [GO:0008270]; chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; histone methylation [GO:0016571]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to fungicide [GO:0060992]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; heterochromatin organization [GO:0070828]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of histone H3-K9 methylation [GO:0051570]; response to ethanol [GO:0045471]	chromatin organization [GO:0006325]; DNA methylation [GO:0006306]; histone methylation [GO:0016571]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of embryonic development [GO:0045995]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to fungicide [GO:0060992]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; histone-lysine N-methyltransferase activity [GO:0018024]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]	C2H2 zinc finger domain binding [GO:0070742]; histone-lysine N-methyltransferase activity [GO:0018024]; histone methyltransferase activity (H3-K27 specific) [GO:0046976]; histone methyltransferase activity (H3-K9 specific) [GO:0046974]; methyltransferase activity [GO:0008168]; p53 binding [GO:0002039]; protein-lysine N-methyltransferase activity [GO:0016279]; zinc ion binding [GO:0008270]
d3osea__d2ooya___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; microtubule cytoskeleton [GO:0015630]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; cytoskeleton organization [GO:0007010]; establishment of mitochondrion localization [GO:0051654]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; neuron migration [GO:0001764]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of dendrite development [GO:0050773]; regulation of neuron projection development [GO:0010975]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; AMP binding [GO:0016208]; ATP binding [GO:0005524]; protein kinase activator activity [GO:0030295]; carbohydrate metabolic process [GO:0005975]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]	cytoskeleton organization [GO:0007010]; establishment of mitochondrion localization [GO:0051654]; intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; neuron migration [GO:0001764]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of dendrite development [GO:0050773]; regulation of neuron projection development [GO:0010975]; Wnt signaling pathway [GO:0016055]	carbohydrate metabolic process [GO:0005975]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; microtubule cytoskeleton [GO:0015630]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylserine binding [GO:0001786]; protein serine/threonine kinase activity [GO:0004674]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]	AMP binding [GO:0016208]; ATP binding [GO:0005524]; protein kinase activator activity [GO:0030295]
d3oskb__d1otsc2__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; regulation of regulatory T cell differentiation [GO:0045589]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein complex involved in cell adhesion [GO:0098636]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3osyb1_d3sufa___1					cysteine-type endopeptidase activity [GO:0004197]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cysteine-type endopeptidase activity [GO:0004197]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3osyc1_d4zh8a___1		Metazoa		Chordata	cysteine-type endopeptidase activity [GO:0004197]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	cysteine-type endopeptidase activity [GO:0004197]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d3ot7a1_d1i08d1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ot7a1_d2cdya1__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ot7a2_d4f2nc2__1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	mitochondrion [GO:0005739]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrion [GO:0005739]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ot7b2_d4yiob2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ot7c2_d3tqjb2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3ot7d1_d4ffka1__1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	cellular response to selenium ion [GO:0071291]; oxidation-reduction process [GO:0055114]; removal of superoxide radicals [GO:0019430]; response to acidic pH [GO:0010447]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		antioxidant activity [GO:0016209]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3otfa__d3ocpa___1	Metazoa	Metazoa	Chordata	Chordata	HCN channel complex [GO:0098855]; intrinsic component of plasma membrane [GO:0031226]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated potassium channel activity involved in SA node cell action potential depolarization [GO:0086041]; voltage-gated sodium channel activity [GO:0005248]; blood circulation [GO:0008015]; cation transport [GO:0006812]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; membrane depolarization during SA node cell action potential [GO:0086046]; muscle contraction [GO:0006936]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane depolarization [GO:0003254]; regulation of membrane potential [GO:0042391]; SA node cell action potential [GO:0086015]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	blood circulation [GO:0008015]; cation transport [GO:0006812]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; membrane depolarization during SA node cell action potential [GO:0086046]; muscle contraction [GO:0006936]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of cardiac muscle cell action potential involved in regulation of contraction [GO:0098909]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane depolarization [GO:0003254]; regulation of membrane potential [GO:0042391]; SA node cell action potential [GO:0086015]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	HCN channel complex [GO:0098855]; intrinsic component of plasma membrane [GO:0031226]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated potassium channel activity involved in SA node cell action potential depolarization [GO:0086041]; voltage-gated sodium channel activity [GO:0005248]	ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]
d3otje__d3f9hb___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3otqa1_d3hych___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipopolysaccharide biosynthetic process [GO:0009103]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d3otra2_d2ggee1__1			Apicomplexa	Firmicutes	phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	glycolytic process [GO:0006096]		phosphopyruvate hydratase complex [GO:0000015]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3otrb1_d3ucca1__1		Metazoa	Apicomplexa	Chordata	phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	phosphopyruvate hydratase complex [GO:0000015]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3otrb2_d2bahd2__1			Apicomplexa		phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		phosphopyruvate hydratase complex [GO:0000015]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	
d3otrd1_d2qjjb1__1			Apicomplexa	Proteobacteria	phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	glycolytic process [GO:0006096]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	phosphopyruvate hydratase complex [GO:0000015]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d3otwa__d1jhda2__1			Proteobacteria		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	coenzyme A biosynthetic process [GO:0015937]	hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d3otwb__d3dv2a___1			Proteobacteria		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]		coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	
d3otwd__d5o0hb___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d3otwf__d1yuna___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	coenzyme A biosynthetic process [GO:0015937]	NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; nicotinamide-nucleotide adenylyltransferase activity [GO:0000309]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]
d3otxb__d5c3yc1__1		Metazoa		Chordata	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycosome [GO:0020015]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; adenosine kinase activity [GO:0004001]; nucleotide binding [GO:0000166]; purine ribonucleoside salvage [GO:0006166]; purine ribonucleotide biosynthetic process [GO:0009152]	cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]	purine ribonucleoside salvage [GO:0006166]; purine ribonucleotide biosynthetic process [GO:0009152]	D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glycosome [GO:0020015]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; nucleus [GO:0005634]	adenosine kinase activity [GO:0004001]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d3ou1b__d3em4a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ou4a__d2zhra___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3ouaa__d5p23a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ouda__d5p2la___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ouna__d1qwtb___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; lipid-linked peptidoglycan transporter activity [GO:0015648]; lipid translocation [GO:0034204]; lipid-linked peptidoglycan transport [GO:0015836]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	lipid-linked peptidoglycan transport [GO:0015836]; lipid translocation [GO:0034204]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	lipid-linked peptidoglycan transporter activity [GO:0015648]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]
d3oupa__d1mr7z___1			Euryarchaeota	Firmicutes	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]			bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	transferase activity, transferring acyl groups [GO:0016746]
d3ouqa2_d2bq4a___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; anaerobic respiration [GO:0009061]		anaerobic respiration [GO:0009061]		periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3ov1a__d2rsya1__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]
d3ov2a2_d1dlud1__1	Viridiplantae		Streptophyta	Proteobacteria	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	flavonoid biosynthetic process [GO:0009813]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3ov2b2_d5wx4c1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	flavonoid biosynthetic process [GO:0009813]	biosynthetic process [GO:0009058]			curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d3ov2d2_d2bywc2__1	Viridiplantae		Streptophyta	Proteobacteria	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d3ov3b1_d2wktc1__1	Viridiplantae		Streptophyta	Proteobacteria	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	flavonoid biosynthetic process [GO:0009813]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3ov3b2_d5wx4a1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	flavonoid biosynthetic process [GO:0009813]	biosynthetic process [GO:0009058]			curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d3ov3c2_d4ubta1__1	Viridiplantae		Streptophyta	Actinobacteria	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]	flavonoid biosynthetic process [GO:0009813]	cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]			curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d3ov3d1_d1j3na1__1	Viridiplantae		Streptophyta	Deinococcus-Thermus	curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; flavonoid biosynthetic process [GO:0009813]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	flavonoid biosynthetic process [GO:0009813]	fatty acid biosynthetic process [GO:0006633]			curcumin synthase activity [GO:0102106]; protein homodimerization activity [GO:0042803]; transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d3ov6a1_d2adga2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ov9b__d4h5lb___1			Negarnaviricota	Negarnaviricota	helical viral capsid [GO:0019029]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]	helical viral capsid [GO:0019029]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]			helical viral capsid [GO:0019029]; viral nucleocapsid [GO:0019013]	helical viral capsid [GO:0019029]; viral nucleocapsid [GO:0019013]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3ovma__d3fx2a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3ovma__d5fuqa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3ovqa__d1km3a___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; ribulose-phosphate 3-epimerase activity [GO:0004750]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3ovqb__d1dbtc___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; ribulose-phosphate 3-epimerase activity [GO:0004750]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3ovub1_d3qzma1__1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cell wall [GO:0005618]; extracellular region [GO:0005576]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	metal ion binding [GO:0046872]
d3ovub1_d4h8pa___1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cell wall [GO:0005618]; extracellular region [GO:0005576]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	metal ion binding [GO:0046872]
d3ovza1_d5qcia1__1	Metazoa	Metazoa	Chordata	Chordata	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d3ow1e1_d3ucdb1__1		Metazoa	Proteobacteria	Chordata	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3ow1f1_d4il2b1__1			Proteobacteria	Proteobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d3ow1f1_d5fjud1__1			Proteobacteria	Actinobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	menaquinone biosynthetic process [GO:0009234]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3ow5a__d1qrfa___1			Euryarchaeota	Euryarchaeota	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]					bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]	bicarbonate binding [GO:0071890]; carbonate dehydratase activity [GO:0004089]; cobalt ion binding [GO:0050897]; sulfate binding [GO:0043199]; zinc ion binding [GO:0008270]
d3ow6a__d1bxda___1	Metazoa		Chordata	Proteobacteria	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]; phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; regulation of response to osmotic stress [GO:0047484]; signal transduction by protein phosphorylation [GO:0023014]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	phosphorelay signal transduction system [GO:0000160]; phosphorylation [GO:0016310]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; regulation of response to osmotic stress [GO:0047484]; signal transduction by protein phosphorylation [GO:0023014]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	cytoplasmic side of plasma membrane [GO:0009898]; integral component of plasma membrane [GO:0005887]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]
d3owec__d5l8kb1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	axon hillock [GO:0043203]; centriole [GO:0005814]; centrosome [GO:0005813]; chromosome passenger complex [GO:0032133]; cilium [GO:0005929]; condensed nuclear chromosome, centromeric region [GO:0000780]; cytosol [GO:0005829]; germinal vesicle [GO:0042585]; meiotic spindle [GO:0072687]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle pole [GO:0097431]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle midzone [GO:0051233]; spindle pole centrosome [GO:0031616]; ATP binding [GO:0005524]; histone serine kinase activity [GO:0035174]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; ubiquitin protein ligase binding [GO:0031625]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; anterior/posterior axis specification [GO:0009948]; cell division [GO:0051301]; centrosome localization [GO:0051642]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; G2/M transition of mitotic cell cycle [GO:0000086]; liver regeneration [GO:0097421]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neuron projection extension [GO:1990138]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autophosphorylation [GO:0046777]; protein localization to centrosome [GO:0071539]; protein phosphorylation [GO:0006468]; regulation of centrosome cycle [GO:0046605]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to wounding [GO:0009611]; spindle assembly involved in female meiosis I [GO:0007057]; spindle organization [GO:0007051]; ubiquitin-dependent protein catabolic process [GO:0006511]	pathogenesis [GO:0009405]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; anterior/posterior axis specification [GO:0009948]; cell division [GO:0051301]; centrosome localization [GO:0051642]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; G2/M transition of mitotic cell cycle [GO:0000086]; liver regeneration [GO:0097421]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neuron projection extension [GO:1990138]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autophosphorylation [GO:0046777]; protein localization to centrosome [GO:0071539]; protein phosphorylation [GO:0006468]; regulation of centrosome cycle [GO:0046605]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to wounding [GO:0009611]; spindle assembly involved in female meiosis I [GO:0007057]; spindle organization [GO:0007051]; ubiquitin-dependent protein catabolic process [GO:0006511]	extracellular region [GO:0005576]	axon hillock [GO:0043203]; centriole [GO:0005814]; centrosome [GO:0005813]; chromosome passenger complex [GO:0032133]; cilium [GO:0005929]; condensed nuclear chromosome, centromeric region [GO:0000780]; cytosol [GO:0005829]; germinal vesicle [GO:0042585]; meiotic spindle [GO:0072687]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle pole [GO:0097431]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle midzone [GO:0051233]; spindle pole centrosome [GO:0031616]		ATP binding [GO:0005524]; histone serine kinase activity [GO:0035174]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625]
d3oweg__d3kprj1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	pathogenesis [GO:0009405]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3owei__d2fx8i1__1			Firmicutes		extracellular region [GO:0005576]; pathogenesis [GO:0009405]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	pathogenesis [GO:0009405]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d3owek__d5gksd1__1			Firmicutes		extracellular region [GO:0005576]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]			
d3oweo__d1kb9j___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]; aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	pathogenesis [GO:0009405]	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	extracellular region [GO:0005576]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrion [GO:0005739]		
d3owha__d1ycfb1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d3owhb__d1xt6a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3owka__d5texa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]; ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; manganese ion binding [GO:0030145]; protein serine/threonine kinase activity [GO:0004674]; ribosomal small subunit binding [GO:0043024]; transcription factor binding [GO:0008134]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular detoxification [GO:1990748]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan metabolic process [GO:0030212]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell population proliferation [GO:0008283]; cellular detoxification [GO:1990748]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan metabolic process [GO:0030212]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardioblast proliferation [GO:1905062]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of transmembrane transporter activity [GO:0022898]; vitamin D receptor signaling pathway [GO:0070561]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; manganese ion binding [GO:0030145]; protein serine/threonine kinase activity [GO:0004674]; ribosomal small subunit binding [GO:0043024]; transcription factor binding [GO:0008134]
d3ox1b__d2f1oe___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3ox2a__d1ja1a2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d3ox2b__d1d4ab___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3ox3a__d5llda2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; nitric oxide catabolic process [GO:0046210]; protein homotetramerization [GO:0051289]; response to nitric oxide [GO:0071731]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	nitric oxide catabolic process [GO:0046210]; protein homotetramerization [GO:0051289]; response to nitric oxide [GO:0071731]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]
d3ox8b1_d3ujtm1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3oxcb__d2f81b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3oxob2_d4oqqb___1	Metazoa		Chordata	Firmicutes	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	carbohydrate binding [GO:0030246]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]		mitochondrion [GO:0005739]		3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]
d3oxoc1_d3bxfa2__1	Metazoa		Chordata	Firmicutes	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	carbohydrate binding [GO:0030246]; DNA binding [GO:0003677]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]		mitochondrion [GO:0005739]		3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; DNA binding [GO:0003677]
d3oxod1_d2wu1b___1	Metazoa		Chordata	Proteobacteria	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	carbohydrate metabolic process [GO:0005975]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	glucosamine-6-phosphate deaminase activity [GO:0004342]; identical protein binding [GO:0042802]
d3oxof1_d3bxgb2__1	Metazoa		Chordata	Firmicutes	mitochondrion [GO:0005739]; 3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]; cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	carbohydrate binding [GO:0030246]; DNA binding [GO:0003677]	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]		mitochondrion [GO:0005739]		3-oxoacid CoA-transferase activity [GO:0008260]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; DNA binding [GO:0003677]
d3oxvc__d4mc6b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3oxvd__d2g1ya___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d3oxwa__d3bgcb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3oxwd__d2pk6a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3oxwd__d5p39a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3oxxd__d2qd8b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3oxxd__d4yd3a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3oy3b1_d4md7f___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; delta-catenin binding [GO:0070097]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; B cell proliferation [GO:0042100]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; integrin-mediated signaling pathway [GO:0007229]; microspike assembly [GO:0030035]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of cellular senescence [GO:2000772]; regulation of extracellular matrix organization [GO:1903053]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]; ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; apoptotic process [GO:0006915]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation [GO:0042100]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; integrin-mediated signaling pathway [GO:0007229]; microspike assembly [GO:0030035]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of cellular senescence [GO:2000772]; regulation of extracellular matrix organization [GO:1903053]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; growth cone [GO:0030426]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear body [GO:0016604]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; delta-catenin binding [GO:0070097]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]	ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]
d3oy4a__d1tw7b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3oy4b__d3o9gb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3oyqa__d3iaic___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3oz7a1_d5m3ua___1		Metazoa	Apicomplexa	Chordata	cytosol [GO:0005829]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; positive regulation of oxidative phosphorylation [GO:1903862]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; membrane raft [GO:0045121]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; protein-disulfide reductase activity [GO:0047134]; canonical glycolysis [GO:0061621]; cellular response to hypoxia [GO:0071456]; epithelial cell differentiation [GO:0030855]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of angiogenesis [GO:0016525]; phosphorylation [GO:0016310]; plasminogen activation [GO:0031639]; positive regulation of oxidative phosphorylation [GO:1903862]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; positive regulation of oxidative phosphorylation [GO:1903862]	canonical glycolysis [GO:0061621]; cellular response to hypoxia [GO:0071456]; epithelial cell differentiation [GO:0030855]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of angiogenesis [GO:0016525]; phosphorylation [GO:0016310]; plasminogen activation [GO:0031639]; positive regulation of oxidative phosphorylation [GO:1903862]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; membrane raft [GO:0045121]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; protein-disulfide reductase activity [GO:0047134]
d3oz9l1_d3ezjf1__1	Metazoa		Chordata	Proteobacteria	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell outer membrane [GO:0009279]; type II protein secretion system complex [GO:0015627]; protein secretion by the type II secretion system [GO:0015628]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	protein secretion by the type II secretion system [GO:0015628]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell outer membrane [GO:0009279]; type II protein secretion system complex [GO:0015627]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3ozda__d4k6of___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; phosphorylase activity [GO:0004645]; S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; interleukin-12-mediated signaling pathway [GO:0035722]; L-methionine salvage from methylthioadenosine [GO:0019509]; methylation [GO:0032259]; nucleobase-containing compound metabolic process [GO:0006139]; purine ribonucleoside salvage [GO:0006166]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	interleukin-12-mediated signaling pathway [GO:0035722]; L-methionine salvage from methylthioadenosine [GO:0019509]; methylation [GO:0032259]; nucleobase-containing compound metabolic process [GO:0006139]; purine ribonucleoside salvage [GO:0006166]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	phosphorylase activity [GO:0004645]; S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]	metal ion binding [GO:0046872]; uridine phosphorylase activity [GO:0004850]
d3ozfd__d4x45a___1		Metazoa	Apicomplexa	Chordata	cytoplasm [GO:0005737]; guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; xanthine phosphoribosyltransferase activity [GO:0000310]; GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]; adenine binding [GO:0002055]; adenine phosphoribosyltransferase activity [GO:0003999]; AMP binding [GO:0016208]; adenine salvage [GO:0006168]; AMP salvage [GO:0044209]; cellular response to insulin stimulus [GO:0032869]; grooming behavior [GO:0007625]; lactation [GO:0007595]; neutrophil degranulation [GO:0043312]; purine ribonucleoside salvage [GO:0006166]; purine-containing compound salvage [GO:0043101]	GMP salvage [GO:0032263]; IMP salvage [GO:0032264]; XMP salvage [GO:0032265]	adenine salvage [GO:0006168]; AMP salvage [GO:0044209]; cellular response to insulin stimulus [GO:0032869]; grooming behavior [GO:0007625]; lactation [GO:0007595]; neutrophil degranulation [GO:0043312]; purine-containing compound salvage [GO:0043101]; purine ribonucleoside salvage [GO:0006166]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; secretory granule lumen [GO:0034774]	guanine phosphoribosyltransferase activity [GO:0052657]; hypoxanthine phosphoribosyltransferase activity [GO:0004422]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; xanthine phosphoribosyltransferase activity [GO:0000310]	adenine binding [GO:0002055]; adenine phosphoribosyltransferase activity [GO:0003999]; AMP binding [GO:0016208]
d3ozmb2_d4e6me2__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]	metal ion binding [GO:0046872]	cellular amino acid catabolic process [GO:0009063]				metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3ozmc1_d4e6mf1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]	metal ion binding [GO:0046872]	cellular amino acid catabolic process [GO:0009063]				metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3ozmc2_d3fj4b2__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]	cellular amino acid catabolic process [GO:0009063]	cellular amino acid catabolic process [GO:0009063]			metal ion binding [GO:0046872]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d3ozme1_d3ujrb1__1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cellular amino acid catabolic process [GO:0009063]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3ozmh2_d1wuea1__1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	cellular amino acid catabolic process [GO:0009063]	menaquinone biosynthetic process [GO:0009234]			metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3ozsa__d3ieig___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; C-terminal protein methylation [GO:0006481]; cellular protein modification process [GO:0006464]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cellular protein modification process [GO:0006464]; C-terminal protein methylation [GO:0006481]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	protein C-terminal carboxyl O-methyltransferase activity [GO:0003880]; protein C-terminal leucine carboxyl O-methyltransferase activity [GO:0018423]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d3ozta__d2z6ua___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	DNA restriction-modification system [GO:0009307]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]		catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]
d3ozua1_d3pt8b___1		Metazoa	Proteobacteria	Mollusca	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3ozua2_d4af7b1__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	photosynthesis [GO:0015979]	cytoplasm [GO:0005737]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	ferredoxin-NADP+ reductase activity [GO:0004324]
d3ozua3_d2rc5c2__1			Proteobacteria	Spirochaetes	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]		cytoplasm [GO:0005737]		FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3ozva2_d1hzea___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	cytosol [GO:0005829]; riboflavin synthase activity [GO:0004746]; riboflavin biosynthetic process [GO:0009231]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	riboflavin synthase activity [GO:0004746]
d3ozvb1_d3aq7b___1			Proteobacteria	Ciliophora	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]		cytoplasm [GO:0005737]		FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3ozwa1_d2hbsc___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3ozwa1_d3aq5b___1			Proteobacteria	Ciliophora	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]		cytoplasm [GO:0005737]		FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3ozwa2_d4e0fb2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	riboflavin binding [GO:1902444]; riboflavin synthase activity [GO:0004746]; protein homotrimerization [GO:0070207]; riboflavin biosynthetic process [GO:0009231]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	protein homotrimerization [GO:0070207]; riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]		FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	riboflavin binding [GO:1902444]; riboflavin synthase activity [GO:0004746]
d3ozwa3_d2xnca2__1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	photosynthesis [GO:0015979]	cytoplasm [GO:0005737]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	ferredoxin-NADP+ reductase activity [GO:0004324]
d3ozya2_d3pwgb2__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	cellular amino acid catabolic process [GO:0009063]	D-glucarate catabolic process [GO:0042838]			metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3ozyb2_d1e9ib1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	cellular amino acid catabolic process [GO:0009063]	glycolytic process [GO:0006096]		cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3p05c2_d3g1ga___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]; aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; viral procapsid maturation [GO:0046797]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	viral procapsid maturation [GO:0046797]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleolus [GO:0044196]; host cell nucleoplasm [GO:0044095]; viral capsid [GO:0019028]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; nucleic acid binding [GO:0003676]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]
d3p05e2_d3h4el2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3p0ca1_d4hasa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; membrane [GO:0016020]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; phosphatidylinositol binding [GO:0035091]; protein kinase binding [GO:0019901]; actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; glucose metabolic process [GO:0006006]; negative regulation of cell migration [GO:0030336]; norepinephrine secretion [GO:0048243]; Rac protein signal transduction [GO:0016601]; regulation of blood pressure [GO:0008217]; regulation of synaptic transmission, GABAergic [GO:0032228]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; immunological synapse [GO:0001772]; nucleoplasm [GO:0005654]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3-phosphate binding [GO:0032266]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; establishment of natural killer cell polarity [GO:0001770]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to plasma membrane [GO:1990126]; signal transduction [GO:0007165]	actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; glucose metabolic process [GO:0006006]; negative regulation of cell migration [GO:0030336]; norepinephrine secretion [GO:0048243]; Rac protein signal transduction [GO:0016601]; regulation of blood pressure [GO:0008217]; regulation of synaptic transmission, GABAergic [GO:0032228]	endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; establishment of natural killer cell polarity [GO:0001770]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to plasma membrane [GO:1990126]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; membrane [GO:0016020]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; immunological synapse [GO:0001772]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; integrin binding [GO:0005178]; phosphatidylinositol binding [GO:0035091]; protein kinase binding [GO:0019901]	phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol binding [GO:0035091]
d3p0cb1_d1gd5a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; membrane [GO:0016020]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; phosphatidylinositol binding [GO:0035091]; protein kinase binding [GO:0019901]; actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; glucose metabolic process [GO:0006006]; negative regulation of cell migration [GO:0030336]; norepinephrine secretion [GO:0048243]; Rac protein signal transduction [GO:0016601]; regulation of blood pressure [GO:0008217]; regulation of synaptic transmission, GABAergic [GO:0032228]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; NADPH oxidase complex [GO:0043020]; neuronal cell body [GO:0043025]; phagolysosome [GO:0032010]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; electron transfer activity [GO:0009055]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; SH3 domain binding [GO:0017124]; superoxide-generating NADPH oxidase activator activity [GO:0016176]; superoxide-generating NADPH oxidase activity [GO:0016175]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; apoptotic process [GO:0006915]; cell redox homeostasis [GO:0045454]; cellular defense response [GO:0006968]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; innate immune response [GO:0045087]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of transcription, DNA-templated [GO:0045893]; protein targeting to membrane [GO:0006612]; respiratory burst [GO:0045730]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; glucose metabolic process [GO:0006006]; negative regulation of cell migration [GO:0030336]; norepinephrine secretion [GO:0048243]; Rac protein signal transduction [GO:0016601]; regulation of blood pressure [GO:0008217]; regulation of synaptic transmission, GABAergic [GO:0032228]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; apoptotic process [GO:0006915]; cell redox homeostasis [GO:0045454]; cellular defense response [GO:0006968]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; innate immune response [GO:0045087]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of transcription, DNA-templated [GO:0045893]; protein targeting to membrane [GO:0006612]; respiratory burst [GO:0045730]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; membrane [GO:0016020]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]	cell [GO:0005623]; cytosol [GO:0005829]; dendrite [GO:0030425]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; NADPH oxidase complex [GO:0043020]; neuronal cell body [GO:0043025]; phagolysosome [GO:0032010]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]	identical protein binding [GO:0042802]; integrin binding [GO:0005178]; phosphatidylinositol binding [GO:0035091]; protein kinase binding [GO:0019901]	electron transfer activity [GO:0009055]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol binding [GO:0035091]; SH3 domain binding [GO:0017124]; superoxide-generating NADPH oxidase activator activity [GO:0016176]; superoxide-generating NADPH oxidase activity [GO:0016175]
d3p0ta1_d5wa9b___1		Metazoa	Actinobacteria	Chordata	catalytic activity [GO:0003824]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]		intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	catalytic activity [GO:0003824]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]
d3p0vl2_d2ak4d1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3p0vl2_d4l29g2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3p0vm1_d3i6gb1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3p0vm2_d1g9ml1__1		Metazoa		Chordata		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]		cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3p0wa2_d2al1a1__1		Fungi	Proteobacteria	Ascomycota		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3p0wb2_d2akzb1__1		Metazoa	Proteobacteria	Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3p0ya1_d5wk4c___1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	
d3p0yl2_d2vlme2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3p10a__d5b8fb1__1			Proteobacteria	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d3p19d__d2nacb1__1			Proteobacteria	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; formate dehydrogenase (NAD+) activity [GO:0008863]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; formate catabolic process [GO:0042183]		formate catabolic process [GO:0042183]		cytoplasm [GO:0005737]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	formate dehydrogenase (NAD+) activity [GO:0008863]; NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3p19d__d3ngxb2__1			Proteobacteria	Euryarchaeota	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]		histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]			nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]
d3p1ca__d5pbta1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleus [GO:0005634]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d3p1cb__d5ktwc1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3p1ha__d4hmia___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3p1ma1_d1fo4a2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	xanthine catabolic process [GO:0009115]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d3p1mb1_d1krhb3__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]; toluene catabolic process [GO:0042203]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	toluene catabolic process [GO:0042203]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]
d3p1mc1_d1r7sb___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3p1mc1_d3p4rn1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d3p1md1_d5h57f___1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; etioplast stroma [GO:0009578]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; electron transport chain [GO:0022900]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	electron transport chain [GO:0022900]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; etioplast stroma [GO:0009578]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3p1mg1_d3lxfb___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3p1mh1_d3faha1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3p1mh1_d5h5jb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	chloroplast [GO:0009507]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d3p2db1_d1uh4a1__1	Metazoa		Chordata	Firmicutes	clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; endocytic vesicle [GO:0030139]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; angiotensin receptor binding [GO:0031701]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]	carbohydrate metabolic process [GO:0005975]	clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; endocytic vesicle [GO:0030139]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	angiotensin receptor binding [GO:0031701]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol binding [GO:0035091]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d3p2db1_d2k7qa1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; endocytic vesicle [GO:0030139]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; angiotensin receptor binding [GO:0031701]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]; actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled receptor internalization [GO:0002031]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; receptor internalization [GO:0031623]; signal transduction [GO:0007165]	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; defense response to virus [GO:0051607]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	clathrin-coated pit [GO:0005905]; cytoplasm [GO:0005737]; endocytic vesicle [GO:0030139]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical dendrite [GO:0097440]; cell-cell junction [GO:0005911]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; Myb complex [GO:0031523]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Z disc [GO:0030018]	angiotensin receptor binding [GO:0031701]; G protein-coupled receptor binding [GO:0001664]; inositol hexakisphosphate binding [GO:0000822]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol binding [GO:0035091]	actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; Fc-gamma receptor I complex binding [GO:0034988]; G protein-coupled receptor binding [GO:0001664]; GTPase binding [GO:0051020]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; mu-type opioid receptor binding [GO:0031852]; potassium channel regulator activity [GO:0015459]; protein homodimerization activity [GO:0042803]; Rac GTPase binding [GO:0048365]; Ral GTPase binding [GO:0017160]; Rho GTPase binding [GO:0017048]; RNA binding [GO:0003723]; SMAD binding [GO:0046332]; small GTPase binding [GO:0031267]; transcription factor binding [GO:0008134]
d3p2va__d3v35a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d3p39f__d3o9tb___1			Negarnaviricota	Negarnaviricota	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; RNA binding [GO:0003723]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	cytosol [GO:0005829]; host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; evasion or tolerance by virus of host immune response [GO:0030683]; modification by virus of host mRNA processing [GO:0046778]; modulation by virus of host cellular process [GO:0019054]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	evasion or tolerance by virus of host immune response [GO:0030683]; modification by virus of host mRNA processing [GO:0046778]; modulation by virus of host cellular process [GO:0019054]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	cytosol [GO:0005829]; host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; nucleoplasm [GO:0005654]	RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d3p3lb__d3gw9a___1			Actinobacteria		heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d3p3ma3_d1tuic2__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3p3ma3_d4pc1a3__1				Proteobacteria		cytoplasm [GO:0005737]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		translation elongation factor activity [GO:0003746]
d3p3mb1_d2gilb___1		Metazoa		Chordata		cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin V binding [GO:0031489]; protein domain specific binding [GO:0019904]; antigen processing and presentation [GO:0019882]; early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; minus-end-directed organelle transport along microtubule [GO:0072385]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine methylation [GO:0018125]; protein localization to Golgi apparatus [GO:0034067]; Rab protein signal transduction [GO:0032482]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; viral process [GO:0016032]		antigen processing and presentation [GO:0019882]; early endosome to Golgi transport [GO:0034498]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; minus-end-directed organelle transport along microtubule [GO:0072385]; neutrophil degranulation [GO:0043312]; peptidyl-cysteine methylation [GO:0018125]; protein localization to Golgi apparatus [GO:0034067]; Rab protein signal transduction [GO:0032482]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; viral process [GO:0016032]		cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin V binding [GO:0031489]; protein domain specific binding [GO:0019904]
d3p3mb3_d4lbza3__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3p3me2_d1vq6b1__1				Euryarchaeota		ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d3p3mf1_d1wb1c5__1												
d3p3mf2_d4ac9a2__1				Euryarchaeota		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; selenocysteine incorporation [GO:0001514]		selenocysteine incorporation [GO:0001514]		cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3p3mf2_d4j0qa2__1				Proteobacteria		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3p3oa1_d2h7qa___1			Actinobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3p3za1_d2a1oa___1			Actinobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3p4ia2_d3ezwe2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d3p4ia2_d3ldoa1__1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	ATF6-mediated unfolded protein response [GO:0036500]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to interleukin-4 [GO:0071353]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; IRE1-mediated unfolded protein response [GO:0036498]; luteolysis [GO:0001554]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; negative regulation of protein homodimerization activity [GO:0090074]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of cell migration [GO:0030335]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein folding in endoplasmic reticulum [GO:0034975]; protein refolding [GO:0042026]; regulation of ATF6-mediated unfolded protein response [GO:1903891]; regulation of IRE1-mediated unfolded protein response [GO:1903894]; regulation of PERK-mediated unfolded protein response [GO:1903897]; regulation of protein folding in endoplasmic reticulum [GO:0060904]; response to cocaine [GO:0042220]; response to methamphetamine hydrochloride [GO:1904313]; response to unfolded protein [GO:0006986]; stress response to metal ion [GO:0097501]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]; ubiquitin-dependent ERAD pathway [GO:0030433]	cytoplasm [GO:0005737]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of endoplasmic reticulum membrane [GO:0030176]; intracellular membrane-bounded organelle [GO:0043231]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; smooth endoplasmic reticulum [GO:0005790]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein domain specific binding [GO:0019904]; protein folding chaperone [GO:0044183]; ribosome binding [GO:0043022]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3p4oe__d3dura___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3p4pb2_d2wp9j2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d3p4pb2_d5c3jb2__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d3p4pn2_d3vrbb2__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]
d3p4rb2_d1h7xd1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d3p4rn2_d1h7wc1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d3p4sn1_d3nvya1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	xanthine catabolic process [GO:0009115]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d3p4va__d3iaid___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3p53a2_d3p53b4__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell cortex [GO:0005938]; cell projection membrane [GO:0031253]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; growth cone [GO:0030426]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; microspike [GO:0044393]; microvillus [GO:0005902]; podosome [GO:0002102]; ruffle [GO:0001726]; stress fiber [GO:0001725]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; drug binding [GO:0008144]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; cell motility [GO:0048870]; cell-cell junction assembly [GO:0007043]; cytokine-mediated signaling pathway [GO:0019221]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of cell polarity [GO:0007163]; microspike assembly [GO:0030035]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of podosome assembly [GO:0071803]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microvillus assembly [GO:0032534]	actin cytoskeleton [GO:0015629]; cell cortex [GO:0005938]; cell projection membrane [GO:0031253]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; growth cone [GO:0030426]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; microspike [GO:0044393]; microvillus [GO:0005902]; podosome [GO:0002102]; ruffle [GO:0001726]; stress fiber [GO:0001725]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; drug binding [GO:0008144]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; cell motility [GO:0048870]; cell-cell junction assembly [GO:0007043]; cytokine-mediated signaling pathway [GO:0019221]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of cell polarity [GO:0007163]; microspike assembly [GO:0030035]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of podosome assembly [GO:0071803]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microvillus assembly [GO:0032534]	actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; cell-cell junction assembly [GO:0007043]; cell migration [GO:0016477]; cell motility [GO:0048870]; cytokine-mediated signaling pathway [GO:0019221]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of cell polarity [GO:0007163]; microspike assembly [GO:0030035]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of podosome assembly [GO:0071803]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microvillus assembly [GO:0032534]	actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; cell-cell junction assembly [GO:0007043]; cell migration [GO:0016477]; cell motility [GO:0048870]; cytokine-mediated signaling pathway [GO:0019221]; establishment of apical/basal cell polarity [GO:0035089]; establishment or maintenance of cell polarity [GO:0007163]; microspike assembly [GO:0030035]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of podosome assembly [GO:0071803]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microvillus assembly [GO:0032534]	actin cytoskeleton [GO:0015629]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection membrane [GO:0031253]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; growth cone [GO:0030426]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; microspike [GO:0044393]; microvillus [GO:0005902]; podosome [GO:0002102]; ruffle [GO:0001726]; stress fiber [GO:0001725]	actin cytoskeleton [GO:0015629]; cell-cell junction [GO:0005911]; cell cortex [GO:0005938]; cell projection membrane [GO:0031253]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; growth cone [GO:0030426]; invadopodium [GO:0071437]; lamellipodium [GO:0030027]; microspike [GO:0044393]; microvillus [GO:0005902]; podosome [GO:0002102]; ruffle [GO:0001726]; stress fiber [GO:0001725]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; drug binding [GO:0008144]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; drug binding [GO:0008144]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]
d3p54a2_d1cxia1__1				Firmicutes	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3p58a__d4xixg___1	Metazoa	Viridiplantae	Chordata	Chlorophyta	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3p5aa__d5tt3e___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3p5da__d4n34c___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d3p5dd__d4s0ub___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	anchored component of membrane [GO:0031225]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; immune system process [GO:0002376]; viral process [GO:0016032]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	immune system process [GO:0002376]; viral process [GO:0016032]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	anchored component of membrane [GO:0031225]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	
d3p5ea__d1u0nc___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d3p5eb__d1b08a1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d3p5ec__d2riaa1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d3p5ed__d1buua1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d3p5fa__d1poza___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; collagen binding [GO:0005518]; hyaluronic acid binding [GO:0005540]; transmembrane signaling receptor activity [GO:0004888]; cartilage development [GO:0051216]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cellular response to fibroblast growth factor stimulus [GO:0044344]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte migration [GO:0050900]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; wound healing, spreading of cells [GO:0044319]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cartilage development [GO:0051216]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte migration [GO:0050900]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; wound healing, spreading of cells [GO:0044319]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	collagen binding [GO:0005518]; hyaluronic acid binding [GO:0005540]; transmembrane signaling receptor activity [GO:0004888]
d3p5fb__d2riac1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d3p5fb__d4j6jd___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d3p5fc__d3ff8d___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; entry of bacterium into host cell [GO:0035635]; extracellular matrix organization [GO:0030198]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; regulation of gene expression [GO:0010468]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; response to toxic substance [GO:0009636]; synapse assembly [GO:0007416]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; apical junction complex [GO:0043296]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; trans-Golgi network [GO:0005802]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3p5fd__d4m17i___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d3p5gb__d4j6kf___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d3p5gd__d1kzb2___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; positive regulation of complement activation [GO:0045917]; positive regulation of protein processing [GO:0010954]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	calcium ion binding [GO:0005509]; galactose binding [GO:0005534]; mannose binding [GO:0005537]; phosphatidylinositol-4-phosphate binding [GO:0070273]; protease binding [GO:0002020]; protein self-association [GO:0043621]
d3p5ha__d1g1qc1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; platelet dense granule membrane [GO:0031088]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; fucose binding [GO:0042806]; glycosphingolipid binding [GO:0043208]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; oligosaccharide binding [GO:0070492]; sialic acid binding [GO:0033691]
d3p5ha__d2q17d___1	Metazoa		Chordata	Actinobacteria	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	endoplasmic reticulum [GO:0005783]; calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]; post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	endoplasmic reticulum [GO:0005783]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	calcium ion binding [GO:0005509]; cupric ion binding [GO:1903135]; Formylglycine-generating oxidase activity [GO:0120147]
d3p5hb__d1uosa___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]		clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	toxin activity [GO:0090729]
d3p5hd__d3g81c1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d3p5ia__d4np2a1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d3p5ib__d1k9ij___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; B cell adhesion [GO:0097323]; cell-cell recognition [GO:0009988]; endocytosis [GO:0006897]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intracellular transport of virus [GO:0075733]; leukocyte cell-cell adhesion [GO:0007159]; modulation by virus of host morphology or physiology [GO:0019048]; peptide antigen transport [GO:0046968]; positive regulation of T cell proliferation [GO:0042102]; regulation of T cell proliferation [GO:0042129]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral genome replication [GO:0019079]; virion attachment to host cell [GO:0019062]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; host cell [GO:0043657]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; peptide antigen binding [GO:0042605]; virion binding [GO:0046790]; virus receptor activity [GO:0001618]
d3p5ic__d2ridb1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d3p5id__d5bzta___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d3p5qa__d4dwtb___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d3p5tn__d1wtba___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202]; AT DNA binding [GO:0003680]; chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; telomeric DNA binding [GO:0042162]; transcription factor binding [GO:0008134]; 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of telomerase RNA reverse transcriptase activity [GO:1905663]; positive regulation of telomere capping [GO:1904355]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of mRNA stability [GO:0043488]; regulation of telomere maintenance [GO:0032204]; regulation of transcription, DNA-templated [GO:0006355]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; RNA catabolic process [GO:0006401]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of telomerase RNA reverse transcriptase activity [GO:1905663]; positive regulation of telomere capping [GO:1904355]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of mRNA stability [GO:0043488]; regulation of telomere maintenance [GO:0032204]; regulation of transcription, DNA-templated [GO:0006355]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; RNA catabolic process [GO:0006401]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202]	exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]	AT DNA binding [GO:0003680]; chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; telomeric DNA binding [GO:0042162]; transcription factor binding [GO:0008134]
d3p5tp__d2dgxa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; peroxisome [GO:0005777]; RNA binding [GO:0003723]; double-strand break repair [GO:0006302]; female meiotic nuclear division [GO:0007143]; negative regulation of phosphatase activity [GO:0010923]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468]	messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	double-strand break repair [GO:0006302]; female meiotic nuclear division [GO:0007143]; negative regulation of phosphatase activity [GO:0010923]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; peroxisome [GO:0005777]	exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3p5tq__d5tbxb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; translation repressor activity [GO:0030371]; mRNA stabilization [GO:0048255]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of translation [GO:0045727]; response to cold [GO:0009409]; response to UV [GO:0009411]; stress granule assembly [GO:0034063]	messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	mRNA stabilization [GO:0048255]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of translation [GO:0045727]; response to cold [GO:0009409]; response to UV [GO:0009411]; stress granule assembly [GO:0034063]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]	mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; small ribosomal subunit rRNA binding [GO:0070181]; translation repressor activity [GO:0030371]
d3p5ya__d3g1he___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3p5za__d1xbya1__1			Euryarchaeota	Proteobacteria	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3p5za__d3ovpb___1		Metazoa	Euryarchaeota	Chordata	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3p5zb__d2zbtb___1			Euryarchaeota	Deinococcus-Thermus	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; pyridoxal phosphate biosynthetic process [GO:0042823]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal phosphate biosynthetic process [GO:0042823]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3p62a1_d2fpya___1		Metazoa	Proteobacteria	Chordata	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; pyrimidine nucleoside biosynthetic process [GO:0046134]; pyrimidine ribonucleotide biosynthetic process [GO:0009220]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to L-arginine [GO:1903576]; response to starvation [GO:0042594]		cytosol [GO:0005829]; integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase activity [GO:0004152]; drug binding [GO:0008144]; FMN binding [GO:0010181]; ubiquinone binding [GO:0048039]
d3p63a__d2w3sc1__1			Cyanobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]					2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3p63b__d3ax9b1__1		Metazoa	Cyanobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d3p63b__d4jwud___1			Cyanobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3p66a__d1hnla___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3p6ca1_d1aqba___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]; fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	extracellular space [GO:0005615]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; lipid droplet [GO:0005811]; nucleus [GO:0005634]	extracellular space [GO:0005615]	fatty acid binding [GO:0005504]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]	retinal binding [GO:0016918]; retinol binding [GO:0019841]; retinol transmembrane transporter activity [GO:0034632]
d3p6na__d4bf4h___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3p6pa__d4do1d___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3p6yc__d1dz5b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]
d3p6yg__d2nz4d___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]
d3p6yl__d1x0fa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202]; AT DNA binding [GO:0003680]; chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; telomeric DNA binding [GO:0042162]; transcription factor binding [GO:0008134]; 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of telomerase RNA reverse transcriptase activity [GO:1905663]; positive regulation of telomere capping [GO:1904355]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of mRNA stability [GO:0043488]; regulation of telomere maintenance [GO:0032204]; regulation of transcription, DNA-templated [GO:0006355]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; RNA catabolic process [GO:0006401]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of telomerase RNA reverse transcriptase activity [GO:1905663]; positive regulation of telomere capping [GO:1904355]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of mRNA stability [GO:0043488]; regulation of telomere maintenance [GO:0032204]; regulation of transcription, DNA-templated [GO:0006355]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; RNA catabolic process [GO:0006401]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; synapse [GO:0045202]	exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]	AT DNA binding [GO:0003680]; chromatin binding [GO:0003682]; histone deacetylase binding [GO:0042826]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; RNA binding [GO:0003723]; sequence-specific DNA binding [GO:0043565]; sequence-specific double-stranded DNA binding [GO:1990837]; telomeric DNA binding [GO:0042162]; transcription factor binding [GO:0008134]
d3p6yp__d2jx2a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	NELF complex [GO:0032021]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chromatin binding [GO:0003682]; RNA binding [GO:0003723]; negative regulation of mRNA polyadenylation [GO:1900364]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	negative regulation of mRNA polyadenylation [GO:1900364]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	NELF complex [GO:0032021]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]	chromatin binding [GO:0003682]; RNA binding [GO:0003723]
d3p71t__d4gf5h___1	Metazoa		Chordata	Actinobacteria	chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]; GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]; apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]	O-methyltransferase activity [GO:0008171]	apoptotic process [GO:0006915]; ceramide metabolic process [GO:0006672]; inactivation of MAPK activity [GO:0000188]; meiotic cell cycle [GO:0051321]; mesoderm development [GO:0007498]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell growth [GO:0030308]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of microtubule binding [GO:1904528]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of DNA replication [GO:0006275]; regulation of growth [GO:0040008]; regulation of microtubule binding [GO:1904526]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; response to lead ion [GO:0010288]; response to organic substance [GO:0010033]; RNA splicing [GO:0008380]; second-messenger-mediated signaling [GO:0019932]		chromosome, centromeric region [GO:0000775]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; microtubule cytoskeleton [GO:0015630]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein phosphatase type 2A complex [GO:0000159]; spindle pole [GO:0000922]; synapse [GO:0045202]		GABA receptor binding [GO:0050811]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein serine/threonine phosphatase activity [GO:0004722]; tau protein binding [GO:0048156]	O-methyltransferase activity [GO:0008171]
d3p72a1_d1s78b2__1	Metazoa	Metazoa	Chordata	Chordata	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; thrombin-activated receptor activity [GO:0015057]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	thrombin-activated receptor activity [GO:0015057]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]
d3p73b__d5u1rd1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3p74a1_d2b4gb___1			Proteobacteria		FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; glycosome [GO:0020015]; nucleoplasm [GO:0005654]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; dihydroorotate dehydrogenase activity [GO:0004152]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; fumarate metabolic process [GO:0006106]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; fumarate metabolic process [GO:0006106]		ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; glycosome [GO:0020015]; nucleoplasm [GO:0005654]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; dihydroorotate dehydrogenase activity [GO:0004152]
d3p74a1_d5kswc___1			Proteobacteria	Firmicutes	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase activity [GO:0004152]; orotate reductase (NADH) activity [GO:0004589]
d3p77a2_d3ciid1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3p77b__d1ymhc2__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]	cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	integral component of membrane [GO:0016021]	cell wall [GO:0005618]; extracellular region [GO:0005576]		IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]
d3p7fc1_d5b1xa1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; CD8-positive, alpha-beta T cell activation [GO:0036037]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; negative regulation of tumor necrosis factor production [GO:0032720]; plasmacytoid dendritic cell antigen processing and presentation [GO:0002470]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; CD8-positive, alpha-beta T cell activation [GO:0036037]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; negative regulation of tumor necrosis factor production [GO:0032720]; plasmacytoid dendritic cell antigen processing and presentation [GO:0002470]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; transmembrane signaling receptor activity [GO:0004888]
d3p7pe__d4n5pe___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3p7qe__d1qicd___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]		cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3p7re__d5taka___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3p7se__d3c89a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d3p7ue__d2j0tc___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	basement membrane [GO:0005604]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; metalloendopeptidase inhibitor activity [GO:0008191]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; zinc ion binding [GO:0008270]; aging [GO:0007568]; cartilage development [GO:0051216]; cell activation [GO:0001775]; cellular protein metabolic process [GO:0044267]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of trophoblast cell migration [GO:1901164]; platelet degranulation [GO:0002576]; positive regulation of cell population proliferation [GO:0008284]; post-translational protein modification [GO:0043687]; regulation of integrin-mediated signaling pathway [GO:2001044]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to organic substance [GO:0010033]; response to peptide hormone [GO:0043434]		aging [GO:0007568]; cartilage development [GO:0051216]; cell activation [GO:0001775]; cellular protein metabolic process [GO:0044267]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of trophoblast cell migration [GO:1901164]; platelet degranulation [GO:0002576]; positive regulation of cell population proliferation [GO:0008284]; post-translational protein modification [GO:0043687]; regulation of integrin-mediated signaling pathway [GO:2001044]; response to cytokine [GO:0034097]; response to hormone [GO:0009725]; response to organic substance [GO:0010033]; response to peptide hormone [GO:0043434]	extracellular region [GO:0005576]	basement membrane [GO:0005604]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; platelet alpha granule lumen [GO:0031093]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; metalloendopeptidase inhibitor activity [GO:0008191]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; zinc ion binding [GO:0008270]
d3p7ue__d3fb0a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3p7xa1_d2wjuf1__1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	thioredoxin peroxidase activity [GO:0008379]	glutathione transferase activity [GO:0004364]
d3p7xa1_d2z9sa___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]; heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]	thioredoxin peroxidase activity [GO:0008379]	heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d3p7xc__d1xw9b___1		Metazoa	Firmicutes	Arthropoda	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; nucleus [GO:0005634]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; glycerol ether metabolic process [GO:0006662]; response to oxidative stress [GO:0006979]	cell [GO:0005623]	cell [GO:0005623]; nucleus [GO:0005634]	thioredoxin peroxidase activity [GO:0008379]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide oxidoreductase activity [GO:0015035]
d3p82a__d5cpma___1			Proteobacteria	Proteobacteria	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d3p83b1_d1dmle1__1			Euryarchaeota		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	host cell nucleus [GO:0042025]; DNA binding [GO:0003677]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]		host cell nucleus [GO:0042025]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	DNA binding [GO:0003677]
d3p83b1_d5a6da1__1			Euryarchaeota	Euryarchaeota	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]			DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d3p83b2_d3v62e2__1		Fungi	Euryarchaeota	Ascomycota	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]		chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]
d3p83c2_d3f1vb2__1			Euryarchaeota	Proteobacteria	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]		cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3p8ga__d1dxp.2__1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3p8ia__d1h7xb2__1		Metazoa	Proteobacteria	Chordata	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]; beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]		beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	4 iron, 4 sulfur cluster binding [GO:0051539]; dihydropyrimidine dehydrogenase (NADP+) activity [GO:0017113]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; uracil binding [GO:0002058]
d3p8wa2_d3i69d2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3p8wa2_d5ecof2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d3p8yb__d1b8aa2__1			Euryarchaeota	Euryarchaeota	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; tRNA aminoacylation for protein translation [GO:0006418]	aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]; aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; aspartyl-tRNA aminoacylation [GO:0006422]	tRNA aminoacylation for protein translation [GO:0006418]	aspartyl-tRNA aminoacylation [GO:0006422]		aminoacyl-tRNA synthetase multienzyme complex [GO:0017101]; cytosol [GO:0005829]	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]	aspartate-tRNA ligase activity [GO:0004815]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d3p8zc__d5wz2a___1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3p92a__d1mbmc___1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; tertiary granule lumen [GO:1904724]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; antimicrobial humoral response [GO:0019730]; cobalamin metabolic process [GO:0009235]; digestion [GO:0007586]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	host cell membrane [GO:0033644]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	antimicrobial humoral response [GO:0019730]; cobalamin metabolic process [GO:0009235]; digestion [GO:0007586]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; tertiary granule lumen [GO:1904724]	host cell membrane [GO:0033644]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3p92a__d1nfwa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; tertiary granule lumen [GO:1904724]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; antimicrobial humoral response [GO:0019730]; cobalamin metabolic process [GO:0009235]; digestion [GO:0007586]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	antimicrobial humoral response [GO:0019730]; cobalamin metabolic process [GO:0009235]; digestion [GO:0007586]; endothelial cell migration [GO:0043542]; neutrophil degranulation [GO:0043312]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; tertiary granule lumen [GO:1904724]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d3p93c1_d1tkkc2__1			Proteobacteria	Firmicutes	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d3p93e1_d2xgza1__1		Fungi	Proteobacteria	Ascomycota	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3p93f1_d1ebha2__1		Fungi	Proteobacteria	Ascomycota	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3p93f1_d3ozmd1__1			Proteobacteria	Proteobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cellular amino acid catabolic process [GO:0009063]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	metal ion binding [GO:0046872]
d3p93h1_d3mznb1__1			Proteobacteria	Proteobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]				gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	glucarate dehydratase activity [GO:0008872]; metal ion binding [GO:0046872]
d3p97c__d5k09c___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d3p99a__d1cmja___1		Fungi		Ascomycota	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3p99b__d1f4ta___1				Crenarchaeota	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; peroxidase activity [GO:0004601]
d3p99b__d5it1c___1				Actinobacteria	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]	aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3p99d__d2z36a1__1				Actinobacteria	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3p9ca1_d4ooia___1	Viridiplantae		Streptophyta	Proteobacteria	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]		pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]			catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]
d3p9fa2_d5ll1a2__1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d3p9ia1_d1kywa1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]; lignin biosynthetic process [GO:0009809]		lignin biosynthetic process [GO:0009809]			catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]
d3p9ib2_d5dstn___1	Viridiplantae	Metazoa	Streptophyta	Chordata	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	anchored component of the cytoplasmic side of the plasma membrane [GO:0098753]; plasma membrane [GO:0005886]; histone-arginine N-methyltransferase activity [GO:0008469]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; histone methylation [GO:0016571]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; protein homooligomerization [GO:0051260]; protein methylation [GO:0006479]; regulation of protein binding [GO:0043393]		histone methylation [GO:0016571]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; protein homooligomerization [GO:0051260]; protein methylation [GO:0006479]; regulation of protein binding [GO:0043393]		anchored component of the cytoplasmic side of the plasma membrane [GO:0098753]; plasma membrane [GO:0005886]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	histone-arginine N-methyltransferase activity [GO:0008469]; identical protein binding [GO:0042802]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d3p9ib2_d5ehic1__1	Viridiplantae		Streptophyta		catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3p9ic2_d5eeha2__1	Viridiplantae		Streptophyta	Actinobacteria	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]; daunorubicin biosynthetic process [GO:1901771]		daunorubicin biosynthetic process [GO:1901771]			catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	methyltransferase activity [GO:0008168]; O-methyltransferase activity [GO:0008171]
d3p9kb1_d2ve9e___1	Viridiplantae		Streptophyta	Proteobacteria	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to antibiotic [GO:0071236]; chromosome segregation [GO:0007059]		cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to antibiotic [GO:0071236]; chromosome segregation [GO:0007059]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	ATP binding [GO:0005524]; DNA binding [GO:0003677]
d3p9kb1_d2zmea1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; ESCRT II complex [GO:0000814]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; structural molecule activity [GO:0005198]; endosomal transport [GO:0016197]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]		endosomal transport [GO:0016197]; macroautophagy [GO:0016236]; multivesicular body assembly [GO:0036258]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; ESCRT II complex [GO:0000814]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; structural molecule activity [GO:0005198]
d3p9kc2_d4ymhd___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	O-methyltransferase activity [GO:0008171]					catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	O-methyltransferase activity [GO:0008171]
d3p9kd2_d5t6bb___1	Viridiplantae		Streptophyta	Actinobacteria	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]					catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; orcinol O-methyltransferase activity [GO:0102938]; protein dimerization activity [GO:0046983]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d3p9le__d2z4qa2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d3p9oa2_d3ld4a1__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d3p9wd__d2dtqb3__1	Metazoa		Chordata		cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	
d3p9wf__d4uimf1__1	Metazoa		Chordata		cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]		cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]	
d3p9xa1_d1cdea___1			Firmicutes	Proteobacteria	phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]; cellular response to DNA damage stimulus [GO:0006974]		cytosol [GO:0005829]	phosphoribosylglycinamide formyltransferase activity [GO:0004644]	phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d3pa9a__d1d2fa___1			Proteobacteria	Proteobacteria	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]	cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; methionine biosynthetic process [GO:0009086]; negative regulation of DNA-binding transcription factor activity [GO:0043433]	biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]	methionine biosynthetic process [GO:0009086]; negative regulation of DNA-binding transcription factor activity [GO:0043433]			pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	cystathionine beta-lyase activity [GO:0004121]; cysteine-S-conjugate beta-lyase activity [GO:0047804]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]
d3pabb__d5hdbf1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3paca1_d5d6va___1			Proteobacteria	Proteobacteria								
d3pajb1_d1yirc2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; quinolinate catabolic process [GO:0034213]	cytosol [GO:0005829]; nicotinate phosphoribosyltransferase activity [GO:0004516]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]	NAD biosynthetic process [GO:0009435]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]; NAD salvage [GO:0034355]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; nicotinate phosphoribosyltransferase activity [GO:0004516]
d3pajb2_d2i14a1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; quinolinate catabolic process [GO:0034213]	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]; NAD biosynthetic process [GO:0009435]	NAD biosynthetic process [GO:0009435]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; quinolinate catabolic process [GO:0034213]	NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]		nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]	metal ion binding [GO:0046872]; nicotinate-nucleotide diphosphorylase (carboxylating) activity [GO:0004514]
d3paqa2_d4gk1g___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	cytokine-mediated signaling pathway [GO:0019221]; Notch signaling pathway [GO:0007219]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; IgE binding [GO:0019863]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]
d3para2_d4n33d___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	cellular response to mechanical stimulus [GO:0071260]; cellular response to nitric oxide [GO:0071732]; circadian rhythm [GO:0007623]; developmental process [GO:0032502]; positive regulation of phagocytosis [GO:0050766]; respiratory gaseous exchange by respiratory system [GO:0007585]; response to epidermal growth factor [GO:0070849]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to interleukin-6 [GO:0070741]; response to lipopolysaccharide [GO:0032496]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	collagen trimer [GO:0005581]; cytoplasmic vesicle [GO:0031410]; extracellular space [GO:0005615]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]
d3pava1_d4ko9c___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3pava2_d1tu2a1__1			Proteobacteria	Cyanobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	integral component of thylakoid membrane [GO:0031361]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	photosynthesis [GO:0015979]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	integral component of thylakoid membrane [GO:0031361]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3paxa1_d1uk0a1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA binding [GO:0003677]; NAD binding [GO:0051287]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]; ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	apoptotic process [GO:0006915]; ATP generation from poly-ADP-D-ribose [GO:1990966]; cellular response to amyloid-beta [GO:1904646]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to UV [GO:0034644]; cellular response to zinc ion [GO:0071294]; DNA ADP-ribosylation [GO:0030592]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of myofibroblast differentiation [GO:1904762]; positive regulation of neuron death [GO:1901216]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of single strand break repair [GO:1903518]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; regulation of catalytic activity [GO:0050790]; regulation of cellular protein localization [GO:1903827]; regulation of DNA methylation [GO:0044030]; regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903376]; regulation of SMAD protein complex assembly [GO:0010990]; response to aldosterone [GO:1904044]; response to gamma radiation [GO:0010332]; signal transduction involved in regulation of gene expression [GO:0023019]; telomere maintenance [GO:0000723]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]	membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; protein-DNA complex [GO:0032993]; site of DNA damage [GO:0090734]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; NAD DNA ADP-ribosyltransferase activity [GO:0140294]; protein ADP-ribosylase activity [GO:1990404]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; R-SMAD binding [GO:0070412]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3paxa2_d2c89c___1	Metazoa		Chordata		chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA binding [GO:0003677]; NAD binding [GO:0051287]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]; ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	extracellular region [GO:0005576]; transferase activity, transferring pentosyl groups [GO:0016763]; pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	ATP generation from poly-ADP-D-ribose [GO:1990966]; DNA ADP-ribosylation [GO:0030592]; double-strand break repair [GO:0006302]; peptidyl-glutamic acid poly-ADP-ribosylation [GO:0018424]; peptidyl-serine ADP-ribosylation [GO:0018312]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212]	pathogenesis [GO:0009405]; protein ADP-ribosylation [GO:0006471]; viral process [GO:0016032]	chromosome [GO:0005694]; nucleolus [GO:0005730]; nucleus [GO:0005634]	extracellular region [GO:0005576]	DNA binding [GO:0003677]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD binding [GO:0051287]; protein ADP-ribosylase activity [GO:1990404]; zinc ion binding [GO:0008270]	transferase activity, transferring pentosyl groups [GO:0016763]
d3paza__d1bxva___1			Proteobacteria	Cyanobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	thylakoid membrane [GO:0042651]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	thylakoid membrane [GO:0042651]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3pb0b1_d5cksd___1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; identical protein binding [GO:0042802]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; identical protein binding [GO:0042802]
d3pb1e__d3rxha___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	digestion [GO:0007586]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3pbda__d2q5kb___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d3pbga__d1bgad___1			Firmicutes	Firmicutes	6-phospho-beta-galactosidase activity [GO:0033920]; lactose catabolic process via tagatose-6-phosphate [GO:0019512]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	lactose catabolic process via tagatose-6-phosphate [GO:0019512]	cellulose catabolic process [GO:0030245]			6-phospho-beta-galactosidase activity [GO:0033920]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3pbua__d4gc4b___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3pbva__d3rlvb___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3pbvb__d5lhfa___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	tryptophan biosynthetic process [GO:0000162]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	phosphoribosylanthranilate isomerase activity [GO:0004640]
d3pbwa__d3ct7f___1			Euryarchaeota	Proteobacteria	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular carbohydrate metabolic process [GO:0044262]; D-allose catabolic process [GO:0019316]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		cytosol [GO:0005829]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	allulose 6-phosphate 3-epimerase activity [GO:0034700]; metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3pbwb__d2zbtd___1			Euryarchaeota	Deinococcus-Thermus	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; pyridoxal phosphate biosynthetic process [GO:0042823]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	pyridoxal phosphate biosynthetic process [GO:0042823]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3pc0a__d3llfa___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3pc6a1_d3qvgd1__1	Metazoa	Metazoa	Chordata	Chordata	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; cerebellum morphogenesis [GO:0021587]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; voluntary musculoskeletal movement [GO:0050882]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; cerebellum morphogenesis [GO:0021587]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; voluntary musculoskeletal movement [GO:0050882]	base-excision repair [GO:0006284]; cerebellum morphogenesis [GO:0021587]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; voluntary musculoskeletal movement [GO:0050882]	base-excision repair [GO:0006284]; cerebellum morphogenesis [GO:0021587]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; voluntary musculoskeletal movement [GO:0050882]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]	enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]
d3pc8a__d1cdza___1	Metazoa	Metazoa	Chordata	Chordata	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; cerebellum morphogenesis [GO:0021587]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; voluntary musculoskeletal movement [GO:0050882]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	base-excision repair [GO:0006284]; cerebellum morphogenesis [GO:0021587]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; voluntary musculoskeletal movement [GO:0050882]	base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]	3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]
d3pcba__d3i4va___1			Proteobacteria	Actinobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]; aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]
d3pcff__d2buua___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d3pcgb__d3mflm___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d3pchc__d2azqa___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	catechol 1,2-dioxygenase activity [GO:0018576]; ferric iron binding [GO:0008199]; catechol-containing compound catabolic process [GO:0019614]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	catechol-containing compound catabolic process [GO:0019614]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	catechol 1,2-dioxygenase activity [GO:0018576]; ferric iron binding [GO:0008199]
d3pcif__d3hjsa___1			Proteobacteria	Actinobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]; aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]
d3pcjf__d3lktr___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d3pckd__d3hhya___1			Proteobacteria	Actinobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]; aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]
d3pcmc__d2buza___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d3pcme__d3i4ya___1			Proteobacteria	Actinobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]; aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	aromatic compound catabolic process [GO:0019439]; catechol-containing compound metabolic process [GO:0009712]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	catechol 1,2-dioxygenase activity [GO:0018576]; chlorocatechol 1,2-dioxygenase activity [GO:0018575]; ferric iron binding [GO:0008199]
d3pcwa__d1hvkb___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3pcwa__d2qzwb___1	Fungi	Fungi	Ascomycota	Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; aspartic-type endopeptidase activity [GO:0004190]; adhesion of symbiont to host [GO:0044406]; fungal-type cell wall organization [GO:0031505]; induction by symbiont of defense-related host calcium ion flux [GO:0052391]; induction by symbiont of host defense response [GO:0044416]; induction by symbiont of host immune response [GO:0052559]; nitrogen compound metabolic process [GO:0006807]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; protein metabolic process [GO:0019538]; proteolysis [GO:0006508]; signal peptide processing [GO:0006465]		adhesion of symbiont to host [GO:0044406]; fungal-type cell wall organization [GO:0031505]; induction by symbiont of defense-related host calcium ion flux [GO:0052391]; induction by symbiont of host defense response [GO:0044416]; induction by symbiont of host immune response [GO:0052559]; nitrogen compound metabolic process [GO:0006807]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; protein metabolic process [GO:0019538]; proteolysis [GO:0006508]; signal peptide processing [GO:0006465]		extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d3pcya__d1jvod___1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane [GO:0009535]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3pd3a__d4rrqb___1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; threonyl-tRNA aminoacylation [GO:0006435]	threonyl-tRNA aminoacylation [GO:0006435]	threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d3pd6c__d1i41i___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell surface [GO:0009986]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; T-tubule [GO:0030315]; amino acid binding [GO:0016597]; carboxylic acid binding [GO:0031406]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; dicarboxylic acid metabolic process [GO:0043648]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; dicarboxylic acid metabolic process [GO:0043648]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]	transsulfuration [GO:0019346]	cell surface [GO:0009986]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; T-tubule [GO:0030315]		amino acid binding [GO:0016597]; carboxylic acid binding [GO:0031406]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d3pd8a__d1n76a1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d3pd8b1_d4nwca___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3pd9b__d2zzxa___1	Metazoa		Chordata	Deinococcus-Thermus	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; lactate transport [GO:0015727]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	lactate transport [GO:0015727]; transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	periplasmic space [GO:0042597]; tripartite ATP-independent periplasmic transporter complex [GO:0031317]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]
d3pdbb__d2f8ja2__1	Metazoa		Chordata	Thermotogae	cell surface [GO:0009986]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; T-tubule [GO:0030315]; amino acid binding [GO:0016597]; carboxylic acid binding [GO:0031406]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; dicarboxylic acid metabolic process [GO:0043648]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]; histidine biosynthetic process [GO:0000105]	2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; dicarboxylic acid metabolic process [GO:0043648]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]	histidine biosynthetic process [GO:0000105]	cell surface [GO:0009986]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; T-tubule [GO:0030315]		amino acid binding [GO:0016597]; carboxylic acid binding [GO:0031406]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]	histidinol-phosphate transaminase activity [GO:0004400]; pyridoxal phosphate binding [GO:0030170]
d3pdbb__d5x30d___1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; T-tubule [GO:0030315]; amino acid binding [GO:0016597]; carboxylic acid binding [GO:0031406]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; dicarboxylic acid metabolic process [GO:0043648]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; dicarboxylic acid metabolic process [GO:0043648]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]	transsulfuration [GO:0019346]	cell surface [GO:0009986]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; myelin sheath [GO:0043209]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; T-tubule [GO:0030315]		amino acid binding [GO:0016597]; carboxylic acid binding [GO:0031406]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]	homocysteine desulfhydrase activity [GO:0047982]; methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d3pdig__d3zkwb___1			Proteobacteria	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]; protein-containing complex assembly [GO:0065003]	metal ion binding [GO:0046872]; iron ion transport [GO:0006826]	nitrogen fixation [GO:0009399]; protein-containing complex assembly [GO:0065003]	iron ion transport [GO:0006826]			4 iron, 4 sulfur cluster binding [GO:0051539]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	metal ion binding [GO:0046872]
d3pdqb__d5pn8a___1	Metazoa	Metazoa	Chordata	Chordata	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d3pdub1_d3vpgc1__1			Proteobacteria	Deinococcus-Thermus	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	L-lactate dehydrogenase activity [GO:0004459]
d3pdub1_d4o6vb___1			Proteobacteria	Proteobacteria	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]						NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	
d3pdud1_d5ixya1__1		Metazoa	Proteobacteria	Chordata	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d3pdud2_d2zyaa2__1			Proteobacteria	Proteobacteria	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; protein homodimerization activity [GO:0042803]; D-gluconate catabolic process [GO:0046177]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]		D-gluconate catabolic process [GO:0046177]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]		cytosol [GO:0005829]	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	identical protein binding [GO:0042802]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; protein homodimerization activity [GO:0042803]
d3pdug1_d4dbzb___1			Proteobacteria	Actinobacteria	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]		antibiotic biosynthetic process [GO:0017000]			NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	oxidoreductase activity [GO:0016491]
d3pdva__d2dkra1__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell adherens junction [GO:0005913]; filamentous actin [GO:0031941]; nucleus [GO:0005634]; stress fiber [GO:0001725]; Z disc [GO:0030018]; actin binding [GO:0003779]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]; actin cytoskeleton organization [GO:0030036]; heart development [GO:0007507]; muscle structure development [GO:0061061]	basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; MPP7-DLG1-LIN7 complex [GO:0097025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; synapse [GO:0045202]; L27 domain binding [GO:0097016]; PDZ domain binding [GO:0030165]; protein domain specific binding [GO:0019904]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]; protein transport [GO:0015031]	actin cytoskeleton organization [GO:0030036]; heart development [GO:0007507]; muscle structure development [GO:0061061]	exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]; protein transport [GO:0015031]	cell-cell adherens junction [GO:0005913]; filamentous actin [GO:0031941]; nucleus [GO:0005634]; stress fiber [GO:0001725]; Z disc [GO:0030018]	basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; MPP7-DLG1-LIN7 complex [GO:0097025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; synapse [GO:0045202]	actin binding [GO:0003779]; metal ion binding [GO:0046872]; muscle alpha-actinin binding [GO:0051371]	L27 domain binding [GO:0097016]; PDZ domain binding [GO:0030165]; protein domain specific binding [GO:0019904]
d3pe1a__d1zwse___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]; ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]; anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	anoikis [GO:0043276]; apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]	autophagosome lumen [GO:0034423]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]	ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein serine/threonine kinase activity [GO:0004674]
d3pe6a__d2pu5b___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; acylglycerol lipase activity [GO:0047372]; lysophospholipase activity [GO:0004622]; protein homodimerization activity [GO:0042803]; acylglycerol acyl-chain remodeling [GO:0036155]; acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; monoacylglycerol catabolic process [GO:0052651]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; aromatic compound catabolic process [GO:0019439]	acylglycerol acyl-chain remodeling [GO:0036155]; acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; monoacylglycerol catabolic process [GO:0052651]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433]	aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]		acylglycerol lipase activity [GO:0047372]; lysophospholipase activity [GO:0004622]; protein homodimerization activity [GO:0042803]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]
d3pedc__d2ju7a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; lysophospholipid:sodium symporter activity [GO:0051978]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	apical cortex [GO:0045179]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; lysophospholipid:sodium symporter activity [GO:0051978]; phospholipid binding [GO:0005543]
d3pefa2_d2iz0c2__1			Proteobacteria	Firmicutes	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]		D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]			NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]
d3pefd2_d2uyyd2__1		Metazoa	Proteobacteria	Chordata	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]		positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase II [GO:0045944]		cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; nucleosome binding [GO:0031491]; oxidoreductase activity [GO:0016491]
d3pefg2_d2iz0a2__1			Proteobacteria	Firmicutes	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]		D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]			NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]
d3peoj__d2c9tg___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3pewa1_d3kqha1__1	Fungi		Ascomycota		cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nuclear membrane [GO:0031965]; nuclear pore cytoplasmic filaments [GO:0044614]; nucleus [GO:0005634]; polysome [GO:0005844]; ATP binding [GO:0005524]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-dependent ATPase activity [GO:0008186]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; translational termination [GO:0006415]; tRNA export from nucleus [GO:0006409]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; translational termination [GO:0006415]; tRNA export from nucleus [GO:0006409]	actin-dependent intracellular transport of virus [GO:0075520]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; microtubule-dependent intracellular transport of viral material [GO:0075519]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation by symbiont of host protein levels [GO:1990219]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cellular bud tip [GO:0005934]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; nuclear membrane [GO:0031965]; nuclear pore cytoplasmic filaments [GO:0044614]; nucleus [GO:0005634]; polysome [GO:0005844]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell endoplasmic reticulum [GO:0044165]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-containing complex [GO:0032991]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; RNA helicase activity [GO:0003724]	actin binding [GO:0003779]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3pfja__d1is4a___1	Fungi	Metazoa	Ascomycota	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]	cellulose catabolic process [GO:0030245]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]
d3pfja__d1q2eb___1	Fungi	Fungi	Ascomycota	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d3pfpb1_d2yceg___1			Actinobacteria	Crenarchaeota	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; manganese ion binding [GO:0030145]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; protein homooligomerization [GO:0051260]	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; protein homooligomerization [GO:0051260]	glycolytic process [GO:0006096]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; manganese ion binding [GO:0030145]	fructose-bisphosphate aldolase activity [GO:0004332]
d3pfta__d4hmvb___1			Actinobacteria	Proteobacteria	FMN binding [GO:0010181]	FMN binding [GO:0010181]; pyridoxamine-phosphate oxidase activity [GO:0004733]; pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]; pyridoxine biosynthetic process [GO:0008615]		pathogenesis [GO:0009405]; phenazine biosynthetic process [GO:0002047]; pyridoxine biosynthetic process [GO:0008615]			FMN binding [GO:0010181]	FMN binding [GO:0010181]; pyridoxamine-phosphate oxidase activity [GO:0004733]
d3pg9b__d1w8sf___1			Thermotogae	Crenarchaeota	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]	fructose-bisphosphate aldolase activity [GO:0004332]
d3pg9c__d2rfgb1__1			Thermotogae	Proteobacteria	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3pg9f__d3pb2f1__1			Thermotogae	Thermotogae	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3pg9g__d5dbte___1			Thermotogae	Firmicutes	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]		cytoplasm [GO:0005737]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; aldehyde-lyase activity [GO:0016832]	deoxyribose-phosphate aldolase activity [GO:0004139]
d3pgfl1_d4yhnb1__1			Proteobacteria		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	
d3pghb1_d3m23a___1	Metazoa	Fungi	Chordata	Ascomycota	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3pghd1_d1s73a___1	Metazoa	Fungi	Chordata	Ascomycota	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3pgia__d3oxxa___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3pgka__d4o33a___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; oxidation-reduction process [GO:0055114]; positive regulation of oxidative phosphorylation [GO:1903862]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; membrane raft [GO:0045121]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; protein-disulfide reductase activity [GO:0047134]; canonical glycolysis [GO:0061621]; cellular response to hypoxia [GO:0071456]; epithelial cell differentiation [GO:0030855]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of angiogenesis [GO:0016525]; phosphorylation [GO:0016310]; plasminogen activation [GO:0031639]; positive regulation of oxidative phosphorylation [GO:1903862]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; oxidation-reduction process [GO:0055114]; positive regulation of oxidative phosphorylation [GO:1903862]	canonical glycolysis [GO:0061621]; cellular response to hypoxia [GO:0071456]; epithelial cell differentiation [GO:0030855]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; negative regulation of angiogenesis [GO:0016525]; phosphorylation [GO:0016310]; plasminogen activation [GO:0031639]; positive regulation of oxidative phosphorylation [GO:1903862]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; membrane raft [GO:0045121]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; protein-disulfide reductase activity [GO:0047134]
d3pgka__d5bt8f1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; oxidation-reduction process [GO:0055114]; positive regulation of oxidative phosphorylation [GO:1903862]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; oxidation-reduction process [GO:0055114]; positive regulation of oxidative phosphorylation [GO:1903862]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]	ATP binding [GO:0005524]; phosphoglycerate kinase activity [GO:0004618]
d3pgla__d5am3a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; protein dephosphorylation [GO:0006470]; regulation of transcription by RNA polymerase II [GO:0006357]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	metal ion binding [GO:0046872]; phosphoprotein phosphatase activity [GO:0004721]; RNA polymerase II CTD heptapeptide repeat phosphatase activity [GO:0008420]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3pgma__d1yjxc___1	Fungi	Metazoa	Ascomycota	Chordata	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]; regulation of glycolytic process [GO:0006110]; regulation of pentose-phosphate shunt [GO:0043456]; respiratory burst [GO:0045730]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; membrane [GO:0016020]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	phosphoglycerate mutase activity [GO:0004619]	bisphosphoglycerate mutase activity [GO:0004082]; hydrolase activity [GO:0016787]; phosphoglycerate mutase activity [GO:0004619]; protein kinase binding [GO:0019901]
d3pgmb__d2enub___1	Fungi		Ascomycota	Deinococcus-Thermus	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	catalytic activity [GO:0003824]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		phosphoglycerate mutase activity [GO:0004619]	catalytic activity [GO:0003824]
d3pgmb__d4odic___1	Fungi		Ascomycota	Apicomplexa	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; phosphoglycerate mutase activity [GO:0004619]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	phosphoglycerate mutase activity [GO:0004619]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	cytosol [GO:0005829]; mitochondrial intermembrane space [GO:0005758]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		phosphoglycerate mutase activity [GO:0004619]	phosphoglycerate mutase activity [GO:0004619]
d3pgta2_d2obkg___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]		dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	
d3pgtb1_d2gtua1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]
d3pgxa__d2h7ma___1			Actinobacteria		oxidoreductase activity [GO:0016491]						oxidoreductase activity [GO:0016491]	
d3pgxc__d4zvva1__1		Metazoa	Actinobacteria	Chordata	oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	oxidoreductase activity [GO:0016491]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d3ph2b__d2jtib___1		Fungi	Cyanobacteria	Ascomycota	thylakoid lumen [GO:0031977]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	photosynthesis [GO:0015979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	thylakoid lumen [GO:0031977]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3ph2b__d4aama1__1			Cyanobacteria	Proteobacteria	thylakoid lumen [GO:0031977]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	photosynthesis [GO:0015979]		thylakoid lumen [GO:0031977]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3ph4a__d4lfkb___1			Firmicutes		ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				ribose-5-phosphate isomerase activity [GO:0004751]	
d3ph4b__d4lflb___1			Firmicutes		ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				ribose-5-phosphate isomerase activity [GO:0004751]	
d3ph5b__d1ab0a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]		brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cellular response to tumor necrosis factor [GO:0071356]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid transport [GO:0015909]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of inflammatory response [GO:0050729]; response to bacterium [GO:0009617]; white fat cell differentiation [GO:0050872]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	hormone receptor binding [GO:0051427]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d3phce__d3phbs1__1		Metazoa	Apicomplexa	Chordata	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]; immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine nucleotide catabolic process [GO:0006195]; purine-containing compound salvage [GO:0043101]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]	nucleoside metabolic process [GO:0009116]	immune response [GO:0006955]; inosine catabolic process [GO:0006148]; interleukin-2 secretion [GO:0070970]; neutrophil degranulation [GO:0043312]; nicotinamide riboside catabolic process [GO:0006738]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide biosynthetic process [GO:0009165]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; purine nucleotide catabolic process [GO:0006195]; response to drug [GO:0042493]; urate biosynthetic process [GO:0034418]		cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]	purine-nucleoside phosphorylase activity [GO:0004731]	drug binding [GO:0008144]; nucleoside binding [GO:0001882]; phosphate ion binding [GO:0042301]; purine nucleobase binding [GO:0002060]; purine-nucleoside phosphorylase activity [GO:0004731]
d3phgb1_d1hwze2__1			Proteobacteria		cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	
d3phgb1_d2c2xa1__1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]
d3phha1_d1nvta2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d3phib1_d2yfhd1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	glutamate biosynthetic process [GO:0006537]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]
d3phma1_d1pnfa1__1	Metazoa		Chordata	Bacteroidetes	cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]; central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]	central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]		cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]
d3phma2_d1pnfa2__1	Metazoa		Chordata	Bacteroidetes	cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]; central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]	central nervous system development [GO:0007417]; fatty acid primary amide biosynthetic process [GO:0062112]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription by RNA polymerase II [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]		cell surface [GO:0009986]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; secretory granule membrane [GO:0030667]; trans-Golgi network [GO:0005802]; transport vesicle membrane [GO:0030658]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; L-ascorbic acid binding [GO:0031418]; peptidylamidoglycolate lyase activity [GO:0004598]; peptidylglycine monooxygenase activity [GO:0004504]; protein kinase binding [GO:0019901]; zinc ion binding [GO:0008270]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]
d3phoa2_d1iqwh1__1												
d3phqa2_d5bo1l1__1		Metazoa		Chordata		adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; growth factor activity [GO:0008083]; Notch binding [GO:0005112]; phospholipid binding [GO:0005543]; structural molecule activity [GO:0005198]; angiogenesis [GO:0001525]; aorta morphogenesis [GO:0035909]; aortic valve morphogenesis [GO:0003180]; blood vessel remodeling [GO:0001974]; cardiac neural crest cell development involved in outflow tract morphogenesis [GO:0061309]; cardiac right ventricle morphogenesis [GO:0003215]; cardiac septum morphogenesis [GO:0060411]; cell fate determination [GO:0001709]; ciliary body morphogenesis [GO:0061073]; distal tubule development [GO:0072017]; endocardial cushion cell development [GO:0061444]; endothelial cell differentiation [GO:0045446]; glomerular visceral epithelial cell development [GO:0072015]; hemopoiesis [GO:0030097]; inner ear auditory receptor cell differentiation [GO:0042491]; keratinocyte differentiation [GO:0030216]; loop of Henle development [GO:0072070]; morphogenesis of an epithelial sheet [GO:0002011]; myoblast differentiation [GO:0045445]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of stem cell differentiation [GO:2000737]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pulmonary artery morphogenesis [GO:0061156]; pulmonary valve morphogenesis [GO:0003184]; regulation of cell population proliferation [GO:0042127]; response to muramyl dipeptide [GO:0032495]; T cell mediated immunity [GO:0002456]		angiogenesis [GO:0001525]; aorta morphogenesis [GO:0035909]; aortic valve morphogenesis [GO:0003180]; blood vessel remodeling [GO:0001974]; cardiac neural crest cell development involved in outflow tract morphogenesis [GO:0061309]; cardiac right ventricle morphogenesis [GO:0003215]; cardiac septum morphogenesis [GO:0060411]; cell fate determination [GO:0001709]; ciliary body morphogenesis [GO:0061073]; distal tubule development [GO:0072017]; endocardial cushion cell development [GO:0061444]; endothelial cell differentiation [GO:0045446]; glomerular visceral epithelial cell development [GO:0072015]; hemopoiesis [GO:0030097]; inner ear auditory receptor cell differentiation [GO:0042491]; keratinocyte differentiation [GO:0030216]; loop of Henle development [GO:0072070]; morphogenesis of an epithelial sheet [GO:0002011]; myoblast differentiation [GO:0045445]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of stem cell differentiation [GO:2000737]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; positive regulation of cardiac epithelial to mesenchymal transition [GO:0062043]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pulmonary artery morphogenesis [GO:0061156]; pulmonary valve morphogenesis [GO:0003184]; regulation of cell population proliferation [GO:0042127]; response to muramyl dipeptide [GO:0032495]; T cell mediated immunity [GO:0002456]		adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; growth factor activity [GO:0008083]; Notch binding [GO:0005112]; phospholipid binding [GO:0005543]; structural molecule activity [GO:0005198]
d3phwf__d5chfc2__1		Metazoa	Negarnaviricota	Chordata	nucleotide binding [GO:0000166]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; modulation by virus of host protein ubiquitination [GO:0039648]; negative stranded viral RNA replication [GO:0039689]; RNA-templated viral transcription [GO:0039696]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	modulation by virus of host protein ubiquitination [GO:0039648]; negative stranded viral RNA replication [GO:0039689]; RNA-templated viral transcription [GO:0039696]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	nucleotide binding [GO:0000166]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3phya__d1bv6a___1			Proteobacteria		identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]				identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	
d3pi0a__d2nxlb___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3pi2a__d1ux9b___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytosol [GO:0005829]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]; fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]		fatty acid oxidation [GO:0019395]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of hepatic stellate cell activation [GO:2000490]; oxygen transport [GO:0015671]; regulation of nitric-oxide synthase activity [GO:0050999]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	catalase activity [GO:0004096]; fatty acid peroxidase activity [GO:0047888]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d3pi6b1_d2qxua___1			Proteobacteria	Firmicutes	hydrolase activity [GO:0016787]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	hydrolase activity [GO:0016787]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d3pi6d1_d4ke9d___1			Proteobacteria	Firmicutes	hydrolase activity [GO:0016787]	acylglycerol lipase activity [GO:0047372]					hydrolase activity [GO:0016787]	acylglycerol lipase activity [GO:0047372]
d3pi8a__d1gh0e___1	Metazoa		Chordata	Cyanobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3pi8d__d1j3yh___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3pi9a__d3uhyb___1	Metazoa	Metazoa	Chordata	Mollusca	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3pi9a__d5nb4c___1	Metazoa		Chordata	Cyanobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3pi9d__d4gy3a___1	Metazoa		Chordata	Cyanobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3piaa__d5x2ti___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3piab__d5nw6a___1	Metazoa	Metazoa	Chordata	Chordata	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	apoptotic process [GO:0006915]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; neuron projection development [GO:0031175]; oxygen transport [GO:0015671]; positive regulation of catalytic activity [GO:0043085]; visual perception [GO:0007601]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3piad__d1s56b___1	Metazoa		Chordata	Actinobacteria	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; detoxification of nitrogen compound [GO:0051410]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; nitric oxide catabolic process [GO:0046210]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d3pilb__d1nwaa1__1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; L-methionine-(S)-S-oxide reductase activity [GO:0036456]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; cellular response to oxidative stress [GO:0034599]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; L-methionine-(S)-S-oxide reductase activity [GO:0036456]; L-methionine:thioredoxin-disulfide S-oxidoreductase activity [GO:0033744]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; cellular protein modification process [GO:0006464]; cellular response to oxidative stress [GO:0034599]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; response to nitrosative stress [GO:0051409]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]	cellular protein modification process [GO:0006464]; cellular response to oxidative stress [GO:0034599]; evasion or tolerance by symbiont of host-produced nitric oxide [GO:0052060]; response to nitrosative stress [GO:0051409]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	L-methionine-(S)-S-oxide reductase activity [GO:0036456]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]	L-methionine:thioredoxin-disulfide S-oxidoreductase activity [GO:0033744]; L-methionine-(S)-S-oxide reductase activity [GO:0036456]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]
d3pilb__d4d7lb___1	Fungi		Ascomycota	Actinobacteria	cytoplasm [GO:0005737]; nucleus [GO:0005634]; L-methionine-(S)-S-oxide reductase activity [GO:0036456]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; cellular response to oxidative stress [GO:0034599]	peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; cellular protein modification process [GO:0006464]	cellular response to oxidative stress [GO:0034599]	cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]; nucleus [GO:0005634]		L-methionine-(S)-S-oxide reductase activity [GO:0036456]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]	peptide-methionine (S)-S-oxide reductase activity [GO:0008113]
d3pita__d4bfwa___1	Metazoa		Chordata	Actinobacteria	plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]; GTPase activity [GO:0003924]; cellular response to leukemia inhibitory factor [GO:1990830]; Ras protein signal transduction [GO:0007265]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cellular response to leukemia inhibitory factor [GO:1990830]; Ras protein signal transduction [GO:0007265]	coenzyme A biosynthetic process [GO:0015937]	plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; GTP-dependent protein binding [GO:0030742]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]
d3pj6a__d3l5ea___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3pj6a__d4k4qb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3pj9b__d6ay1h___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3pjda__d5jsfa1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	cytosol [GO:0005829]; membrane [GO:0016020]	cytosol [GO:0005829]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]
d3pjea__d3oidd1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]	cytosol [GO:0005829]; membrane [GO:0016020]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3pjka2_d1a9co___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d3pk3a1_d1sqlh___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytosol [GO:0005829]	urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]
d3pk3a2_d5m98a1__1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d3pk4a2_d1r51a1__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d3pk5a2_d4ntkd___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	queuosine biosynthetic process [GO:0008616]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d3pk5a2_d4xfpb1__1	Fungi		Ascomycota	Firmicutes	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]; allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	carboxy-lyase activity [GO:0016831]; urate oxidase activity [GO:0004846]
d3pk6a1_d3i2bg___1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	urate oxidase activity [GO:0004846]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d3pk6a2_d1rrya___1	Fungi		Ascomycota	Firmicutes	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]
d3pk7b1_d3b97c1__1		Metazoa	Proteobacteria	Chordata	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]		cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d3pk7h1_d1mdla2__1			Proteobacteria	Proteobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d3pkfa2_d1a8ri___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d3pkfa2_d4n9ma1__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d3pkha2_d1b66a___1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; tetrahydrobiopterin biosynthetic process [GO:0006729]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	tetrahydrobiopterin biosynthetic process [GO:0006729]	peroxisome [GO:0005777]	mitochondrion [GO:0005739]	urate oxidase activity [GO:0004846]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d3pkla1_d2dj6c___1	Fungi		Ascomycota	Euryarchaeota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	metal ion binding [GO:0046872]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	metal ion binding [GO:0046872]
d3pkla2_d1vaxe2__1	Fungi		Ascomycota		peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	
d3pkpa__d1g3lb___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]			glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d3pkpa__d1j8wb1__1			Proteobacteria		glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]				glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]	
d3pkpi__d2xw4a___1			Proteobacteria		glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]				glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]	
d3pkpj__d3u2ua1__1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]; glycogenin glucosyltransferase activity [GO:0008466]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity [GO:0102751]; glycogen biosynthetic process [GO:0005978]; neutrophil degranulation [GO:0043312]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	glycogen biosynthetic process [GO:0005978]; neutrophil degranulation [GO:0043312]		cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; magnesium ion binding [GO:0000287]	glycogenin glucosyltransferase activity [GO:0008466]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity [GO:0102751]
d3pksa2_d1n3rc___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d3pkzf__d1zr4d2__1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]; transposition [GO:0032196]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]	DNA integration [GO:0015074]; transposition [GO:0032196]	DNA integration [GO:0015074]			DNA binding [GO:0003677]; recombinase activity [GO:0000150]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]
d3pkzl__d2rslb___1			Firmicutes	Proteobacteria	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]; transposition [GO:0032196]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]; DNA integration [GO:0015074]	DNA integration [GO:0015074]; transposition [GO:0032196]	DNA integration [GO:0015074]			DNA binding [GO:0003677]; recombinase activity [GO:0000150]	DNA binding [GO:0003677]; recombinase activity [GO:0000150]
d3pl3a__d2g4ia___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cellulose catabolic process [GO:0030245]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3pl6a2_d3c5sa1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3pl6a2_d5wt9l1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		
d3pl6c2_d1d3la1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]
d3pl6c2_d1rzif2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]			
d3plea1_d3i2be___1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; 6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; cofactor metabolic process [GO:0051186]; tetrahydrobiopterin biosynthetic process [GO:0006729]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	urate oxidase activity [GO:0004846]	6-pyruvoyltetrahydropterin synthase activity [GO:0003874]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d3plea2_d2nm2d___1	Fungi		Ascomycota	Firmicutes	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]
d3plha1_d3o1kd___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]
d3plja2_d1gtpr___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]; GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]; 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; queuosine biosynthetic process [GO:0008616]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	GTP binding [GO:0005525]; GTP cyclohydrolase I activity [GO:0003934]; zinc ion binding [GO:0008270]
d3plja2_d2zkaa1__1	Fungi	Fungi	Ascomycota	Ascomycota	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d3plka__d1lhg.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d3plka__d4fvba___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3plqa__d1lb2a2__1	Metazoa		Chordata	Proteobacteria	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3plyb__d4yl4a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3pm1a2_d5eyra2__1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	cytosol [GO:0005829]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytosol [GO:0005829]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d3pm3a__d4xdea1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; calcium ion binding [GO:0005509]; misfolded protein binding [GO:0051787]; serine-type endopeptidase activity [GO:0004252]; blood coagulation, intrinsic pathway [GO:0007597]; Factor XII activation [GO:0002542]; fibrinolysis [GO:0042730]; innate immune response [GO:0045087]; plasma kallikrein-kinin cascade [GO:0002353]; positive regulation of blood coagulation [GO:0030194]; positive regulation of fibrinolysis [GO:0051919]; positive regulation of plasminogen activation [GO:0010756]; protein autoprocessing [GO:0016540]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to misfolded protein [GO:0051788]; zymogen activation [GO:0031638]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation, intrinsic pathway [GO:0007597]; Factor XII activation [GO:0002542]; fibrinolysis [GO:0042730]; innate immune response [GO:0045087]; plasma kallikrein-kinin cascade [GO:0002353]; positive regulation of blood coagulation [GO:0030194]; positive regulation of fibrinolysis [GO:0051919]; positive regulation of plasminogen activation [GO:0010756]; protein autoprocessing [GO:0016540]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to misfolded protein [GO:0051788]; zymogen activation [GO:0031638]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; misfolded protein binding [GO:0051787]; serine-type endopeptidase activity [GO:0004252]
d3pmfa__d1stna___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3pmja__d3vb3a___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3pmla1_d8icqa1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d3pmrb__d3umia___1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; alpha-2A adrenergic receptor binding [GO:0031694]; alpha-2B adrenergic receptor binding [GO:0031695]; alpha-2C adrenergic receptor binding [GO:0031696]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cellular response to norepinephrine stimulus [GO:0071874]; endocytosis [GO:0006897]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; nervous system development [GO:0007399]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cellular response to norepinephrine stimulus [GO:0071874]; endocytosis [GO:0006897]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; nervous system development [GO:0007399]	activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid-beta clearance [GO:1900221]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	basement membrane [GO:0005604]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi lumen [GO:0005796]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]	alpha-2A adrenergic receptor binding [GO:0031694]; alpha-2B adrenergic receptor binding [GO:0031695]; alpha-2C adrenergic receptor binding [GO:0031696]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]	acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]
d3pmsa1_d3pmsa2__1			Bacteroidetes	Bacteroidetes	hydrolase activity, acting on glycosyl bonds [GO:0016798]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]					hydrolase activity, acting on glycosyl bonds [GO:0016798]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]	hydrolase activity, acting on glycosyl bonds [GO:0016798]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [GO:0016715]; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [GO:0000224]
d3pmva1_d5l9oa___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	membrane [GO:0016020]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ligand-gated ion channel activity [GO:0015276]
d3pmwa__d3bfud___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3pmya__d1msma___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3pmzj1_d1i9bb1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3pnaa__d2gzwd2__1	Metazoa		Chordata	Proteobacteria	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3po7a2_d1b4va2__1	Metazoa		Chordata	Actinobacteria	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	extracellular region [GO:0005576]; cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]; cholesterol metabolic process [GO:0008203]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cholesterol metabolic process [GO:0008203]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	cholesterol oxidase activity [GO:0016995]; flavin adenine dinucleotide binding [GO:0050660]; steroid delta-isomerase activity [GO:0004769]
d3po7b2_d3cpig3__1	Metazoa	Fungi	Chordata	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]
d3pomb2_d4cfmb2__1	Metazoa	Metazoa	Chordata	Chordata	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]; androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d3pote2_d5n2ab2__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	cytoplasm [GO:0005737]		coenzyme-B sulfoethylthiotransferase activity [GO:0050524]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]
d3pp3k2_d5hsfb___1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3pp3l1_d2ybrh___1		Metazoa		Arthropoda		extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]		defense response [GO:0006952]		extracellular region [GO:0005576]		sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]
d3pp6a__d4imoa___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; lipid binding [GO:0008289]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]		cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	cytoplasm [GO:0005737]; membrane [GO:0016020]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	lipid binding [GO:0008289]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d3pp6b__d1yupa1__1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; lipid binding [GO:0008289]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]			cytoplasm [GO:0005737]; membrane [GO:0016020]	extracellular region [GO:0005576]	lipid binding [GO:0008289]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]
d3ppoa__d1quka___1			Firmicutes	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; amino acid transport [GO:0006865]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	amino acid transport [GO:0006865]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	transmembrane transporter activity [GO:0022857]	phosphate ion binding [GO:0042301]
d3ppob__d2dfzb___1			Firmicutes		ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; amino acid transport [GO:0006865]		amino acid transport [GO:0006865]		ATP-binding cassette (ABC) transporter complex [GO:0043190]		transmembrane transporter activity [GO:0022857]	
d3ppob__d5h71a___1			Firmicutes	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; amino acid transport [GO:0006865]	metal ion binding [GO:0046872]	amino acid transport [GO:0006865]		ATP-binding cassette (ABC) transporter complex [GO:0043190]		transmembrane transporter activity [GO:0022857]	metal ion binding [GO:0046872]
d3pppa__d3w9vb___1			Firmicutes		ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; amino acid transport [GO:0006865]	extracellular region [GO:0005576]; phosphate ion transport [GO:0006817]	amino acid transport [GO:0006865]	phosphate ion transport [GO:0006817]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	extracellular region [GO:0005576]	transmembrane transporter activity [GO:0022857]	
d3ppqb__d4h5fc___1			Firmicutes	Firmicutes	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; amino acid transport [GO:0006865]	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	amino acid transport [GO:0006865]		ATP-binding cassette (ABC) transporter complex [GO:0043190]	membrane [GO:0016020]	transmembrane transporter activity [GO:0022857]	ligand-gated ion channel activity [GO:0015276]
d3ppra__d1mpda___1			Firmicutes	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; amino acid transport [GO:0006865]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	amino acid transport [GO:0006865]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	transmembrane transporter activity [GO:0022857]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3ppsa1_d1npja1__1	Fungi		Ascomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3ppsa1_d2qt6b2__1	Fungi	Fungi	Ascomycota	Basidiomycota	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]					copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3ppsa2_d2ux6a___1	Fungi		Ascomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3ppsa3_d2plta___1	Fungi	Viridiplantae	Ascomycota	Chlorophyta	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3ppsa3_d3t6za3__1	Fungi	Fungi	Ascomycota	Basidiomycota	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]					copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3ppsb1_d1zdsa1__1	Fungi		Ascomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3ppsb2_d2iwka2__1	Fungi		Ascomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]		denitrification pathway [GO:0019333]		membrane [GO:0016020]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d3ppsc2_d2ih8a1__1	Fungi	Fungi	Ascomycota	Ascomycota	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3ppsc3_d3jtbb___1	Fungi		Ascomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3ppsd1_d2b08b2__1	Fungi		Ascomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3ppsd1_d4m4rb1__1	Fungi	Metazoa	Ascomycota	Chordata	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	adherens junction [GO:0005912]; anchored component of external side of plasma membrane [GO:0031362]; basement membrane [GO:0005604]; caveola [GO:0005901]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]; chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; neurotrophin TRKA receptor binding [GO:0005168]; neurotrophin TRKB receptor binding [GO:0005169]; neurotrophin TRKC receptor binding [GO:0005170]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; axon guidance [GO:0007411]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to forskolin [GO:1904322]; collateral sprouting [GO:0048668]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; nervous system development [GO:0007399]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell morphogenesis [GO:0022604]; regulation of cell-cell adhesion [GO:0022407]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of microtubule cytoskeleton organization [GO:0070507]; retinal ganglion cell axon guidance [GO:0031290]; synaptic membrane adhesion [GO:0099560]		axon guidance [GO:0007411]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to forskolin [GO:1904322]; collateral sprouting [GO:0048668]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; nervous system development [GO:0007399]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell morphogenesis [GO:0022604]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of microtubule cytoskeleton organization [GO:0070507]; retinal ganglion cell axon guidance [GO:0031290]; synaptic membrane adhesion [GO:0099560]		adherens junction [GO:0005912]; anchored component of external side of plasma membrane [GO:0031362]; basement membrane [GO:0005604]; caveola [GO:0005901]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; neurotrophin TRKA receptor binding [GO:0005168]; neurotrophin TRKB receptor binding [GO:0005169]; neurotrophin TRKC receptor binding [GO:0005170]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]
d3ppsd2_d1kyaa3__1	Fungi	Fungi	Ascomycota	Basidiomycota	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]					copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3ppsd3_d4n20a1__1	Fungi	Metazoa	Ascomycota	Chordata	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; chromatin-mediated maintenance of transcription [GO:0048096]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]		cellular response to leukemia inhibitory factor [GO:1990830]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin organization [GO:0006325]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]
d3pq2a2_d1jdbl2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d3pq2b2_d1p7yd1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3pq3b2_d1p7ya1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3pq4c2_d1jdbf2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d3pq4d2_d1ce8b2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d3pq5c2_d1gg9d1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3pq6a2_d1p7za1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3pq6c2_d2nv2d___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]; glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]; glutaminase complex [GO:1903600]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	glutaminase activity [GO:0004359]; identical protein binding [GO:0042802]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3pq7a2_d3zr4f___1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; histidine biosynthetic process [GO:0000105]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	histidine biosynthetic process [GO:0000105]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]
d3pq8a2_d4envd2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3pq8d2_d2ab0a1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; hydrolase activity [GO:0016787]; protein deglycase activity [GO:0036524]; cellular response to oxidative stress [GO:0034599]; DNA repair [GO:0006281]; guanine deglycation, glyoxal removal [GO:0106046]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycosylation [GO:0006517]; protein refolding [GO:0042026]; protein repair [GO:0030091]; response to heat [GO:0009408]; ribosome biogenesis [GO:0042254]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; DNA repair [GO:0006281]; guanine deglycation, glyoxal removal [GO:0106046]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycosylation [GO:0006517]; protein refolding [GO:0042026]; protein repair [GO:0030091]; response to heat [GO:0009408]; ribosome biogenesis [GO:0042254]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	hydrolase activity [GO:0016787]; protein deglycase activity [GO:0036524]
d3pqda1_d1hsoa2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; alcohol metabolic process [GO:0006066]; drug metabolic process [GO:0017144]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	glycolytic process [GO:0006096]	alcohol metabolic process [GO:0006066]; drug metabolic process [GO:0017144]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	L-lactate dehydrogenase activity [GO:0004459]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d3pqdb2_d3wswb2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d3pqdf2_d3pqfc2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d3pqea2_d2hjrb2__1			Firmicutes	Apicomplexa	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3pqfc1_d1jqbc2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]
d3pr2a__d3lhza___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3pr9a__d4dipg___1		Metazoa	Euryarchaeota	Chordata	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	endoplasmic reticulum lumen [GO:0005788]; calcium ion binding [GO:0005509]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; IRE1-mediated unfolded protein response [GO:0036498]		IRE1-mediated unfolded protein response [GO:0036498]		endoplasmic reticulum lumen [GO:0005788]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	calcium ion binding [GO:0005509]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d3pr9a__d4drja___1		Metazoa	Euryarchaeota	Chordata	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein-containing complex localization [GO:0031503]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]		androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein-containing complex localization [GO:0031503]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]		axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]
d3prla__d3v9kb1__1		Metazoa	Firmicutes	Chordata	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; nucleotide binding [GO:0000166]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; identical protein binding [GO:0042802]; proline catabolic process to glutamate [GO:0010133]		proline catabolic process to glutamate [GO:0010133]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; nucleotide binding [GO:0000166]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; identical protein binding [GO:0042802]
d3prld1_d1o02g___1		Metazoa	Firmicutes	Chordata	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; nucleotide binding [GO:0000166]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; nucleotide binding [GO:0000166]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3prmb__d3r3mb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]
d3prmb__d3wwqg___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3prmd__d3wanb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autolysosome [GO:0044754]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; microtubule [GO:0005874]; organelle membrane [GO:0031090]; synapse [GO:0045202]; microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; phospholipid binding [GO:0005543]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	autolysosome [GO:0044754]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; microtubule [GO:0005874]; organelle membrane [GO:0031090]; synapse [GO:0045202]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; phospholipid binding [GO:0005543]; ubiquitin protein ligase binding [GO:0031625]
d3prpb__d2rsua___1	Metazoa	Metazoa	Chordata	Chordata	ribosome [GO:0005840]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	translation [GO:0006412]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	ribosome [GO:0005840]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]	structural constituent of ribosome [GO:0003735]	protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d3prsa__d3oxvc___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3prva__d6ay1c___1				Proteobacteria	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3prvf__d1nhkl___1				Proteobacteria	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ps4a1_d3nghb1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein serine/threonine kinase activity [GO:0004674]; brain development [GO:0007420]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]; carnitine transport [GO:0015879]; in utero embryonic development [GO:0001701]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; protein localization to plasma membrane [GO:0072659]; regulation of anion transport [GO:0044070]	brain development [GO:0007420]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]	carnitine transport [GO:0015879]; in utero embryonic development [GO:0001701]; positive regulation of cation transmembrane transport [GO:1904064]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of protein targeting to membrane [GO:0090314]; protein localization to plasma membrane [GO:0072659]; regulation of anion transport [GO:0044070]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; membrane raft [GO:0045121]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein serine/threonine kinase activity [GO:0004674]	PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; scavenger receptor binding [GO:0005124]
d3ps7b__d5o0wb___1			Proteobacteria		cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]		4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	fructose-bisphosphate aldolase activity [GO:0004332]
d3psca1_d2bt2b1__1	Metazoa	Metazoa	Chordata	Chordata	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; visual perception [GO:0007601]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; visual perception [GO:0007601]	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]	cytoplasm [GO:0005737]; intrinsic component of membrane [GO:0031224]; plasma membrane [GO:0005886]	G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]	calmodulin binding [GO:0005516]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]
d3psna1_d2ushb2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer complex [GO:0030904]; retromer, cargo-selective complex [GO:0030906]; metal ion binding [GO:0046872]; endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]	outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]	endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]	nucleotide catabolic process [GO:0009166]	cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; retromer, cargo-selective complex [GO:0030906]; retromer complex [GO:0030904]	outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]
d3psra__d1iq5a___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	calcium-mediated signaling [GO:0019722]	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]
d3psua__d3nu5b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3pswa__d1htia___1		Metazoa	Apicomplexa	Chordata	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]
d3psya__d2r5pc___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3pt2b__d1y8rf___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; SUMO activating enzyme complex [GO:0031510]; ATP binding [GO:0005524]; enzyme activator activity [GO:0008047]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; small protein activating enzyme binding [GO:0044388]; SUMO activating enzyme activity [GO:0019948]; SUMO binding [GO:0032183]; transcription factor binding [GO:0008134]; transferase activity [GO:0016740]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; protein modification by small protein conjugation [GO:0032446]; protein sumoylation [GO:0016925]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	protein modification by small protein conjugation [GO:0032446]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; SUMO activating enzyme complex [GO:0031510]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; enzyme activator activity [GO:0008047]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; small protein activating enzyme binding [GO:0044388]; SUMO activating enzyme activity [GO:0019948]; SUMO binding [GO:0032183]; transcription factor binding [GO:0008134]; transferase activity [GO:0016740]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]
d3pt2b__d2aehb3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]; ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]; actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	actin filament organization [GO:0007015]; angiogenesis [GO:0001525]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; regulation of cell adhesion [GO:0030155]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sarcolemma [GO:0042383]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protease binding [GO:0002020]; protein tyrosine kinase activity [GO:0004713]
d3pt7b__d1yhuu___1	Metazoa	Metazoa	Mollusca	Annelida	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3pt8a__d3wcub___1	Metazoa	Metazoa	Mollusca	Annelida	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3ptba__d4a6la___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3ptfa1_d1j7da___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	ubiquitin conjugating enzyme activity [GO:0061631]
d3ptka__d2gftb___1	Viridiplantae		Streptophyta	Firmicutes	extracellular region [GO:0005576]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]	metabolic process [GO:0008152]	extracellular region [GO:0005576]		beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metal ion binding [GO:0046872]
d3ptkb__d1m04a1__1	Viridiplantae		Streptophyta	Actinobacteria	extracellular region [GO:0005576]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]	beta-N-acetylhexosaminidase activity [GO:0004563]
d3ptma__d1ud3a2__1	Viridiplantae		Streptophyta	Firmicutes	extracellular region [GO:0005576]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]	calcium ion binding [GO:0005509]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3ptma__d3aztb___1	Viridiplantae		Streptophyta	Thermotogae	extracellular region [GO:0005576]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3ptmb__d5nave___1	Viridiplantae		Streptophyta	Firmicutes	extracellular region [GO:0005576]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3ptqa__d1gqlb1__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	carbohydrate metabolic process [GO:0005975]	glucuronoxylan catabolic process [GO:2000886]	extracellular region [GO:0005576]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]	beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]	alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]
d3ptqb__d1f49d5__1	Viridiplantae		Streptophyta		extracellular region [GO:0005576]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]		beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; scopolin beta-glucosidase activity [GO:0102483]	
d3puca1_d3tzvg1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3puda__d1ok4f___1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	fructose-bisphosphate aldolase activity [GO:0004332]
d3pudb__d4onva___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; 2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]; aldonic acid catabolic process [GO:0046176]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aldonic acid catabolic process [GO:0046176]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]
d3puia2_d1px3d3__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]; cocaine catabolic process [GO:0050784]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cocaine catabolic process [GO:0050784]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]	beta-galactosidase complex [GO:0009341]	carboxylic ester hydrolase activity [GO:0052689]; dipeptidyl-peptidase activity [GO:0008239]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3pulb__d3lcwd___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d3puoa__d1epxb___1			Proteobacteria		cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]		4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	fructose-bisphosphate aldolase activity [GO:0004332]
d3puva1_d1m8pa3__1		Fungi	Proteobacteria	Ascomycota	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cytoplasm [GO:0005737]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cytoplasm [GO:0005737]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d3puva1_d2onja1__1			Proteobacteria	Firmicutes	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]
d3puxb1_d1l2tb___1			Proteobacteria	Euryarchaeota	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; transmembrane transporter activity [GO:0022857]; transmembrane transport [GO:0055085]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	plasma membrane [GO:0005886]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; transmembrane transporter activity [GO:0022857]
d3puza2_d1oxsc1__1			Proteobacteria	Crenarchaeota	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; carbohydrate transport [GO:0008643]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	carbohydrate transport [GO:0008643]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]
d3puze__d4o3ac1__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3pv0b1_d5ftkd3__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d3pv0e__d5mfva___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d3pv4a1_d4h11b1__1		Metazoa	Proteobacteria	Chordata	serine-type endopeptidase activity [GO:0004252]	anchored component of postsynaptic density membrane [GO:0099031]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of phosphatase activity [GO:0010923]; neuronal ion channel clustering [GO:0045161]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]		cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of phosphatase activity [GO:0010923]; neuronal ion channel clustering [GO:0045161]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]		anchored component of postsynaptic density membrane [GO:0099031]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; juxtaparanode region of axon [GO:0044224]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]	serine-type endopeptidase activity [GO:0004252]	PDZ domain binding [GO:0030165]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]
d3pvaf__d1vsyp___1			Firmicutes		penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]				penicillin amidase activity [GO:0008953]	
d3pvjc__d4bhfa2__1		Metazoa	Proteobacteria	Chordata	dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]; carnitine biosynthetic process [GO:0045329]		carnitine biosynthetic process [GO:0045329]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]	gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]
d3pvjc__d5c3rd___1		Fungi	Proteobacteria	Ascomycota	dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]					dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3pvjd__d3d8ca1__1		Metazoa	Proteobacteria	Chordata	dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; 2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; ankyrin repeat binding [GO:0071532]; carboxylic acid binding [GO:0031406]; cofactor binding [GO:0048037]; hypoxia-inducible factor-asparagine oxygenase activity [GO:0102113]; iron ion binding [GO:0005506]; NF-kappaB binding [GO:0051059]; Notch binding [GO:0005112]; oxygen sensor activity [GO:0019826]; peptidyl-asparagine 3-dioxygenase activity [GO:0036140]; peptidyl-histidine dioxygenase activity [GO:0036139]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; oxidation-reduction process [GO:0055114]; peptidyl-asparagine hydroxylation [GO:0042265]; peptidyl-aspartic acid hydroxylation [GO:0042264]; peptidyl-histidine hydroxylation [GO:0036138]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of vasculogenesis [GO:2001214]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]		negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; oxidation-reduction process [GO:0055114]; peptidyl-asparagine hydroxylation [GO:0042265]; peptidyl-aspartic acid hydroxylation [GO:0042264]; peptidyl-histidine hydroxylation [GO:0036138]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of vasculogenesis [GO:2001214]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]	2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; ankyrin repeat binding [GO:0071532]; carboxylic acid binding [GO:0031406]; cofactor binding [GO:0048037]; hypoxia-inducible factor-asparagine oxygenase activity [GO:0102113]; iron ion binding [GO:0005506]; NF-kappaB binding [GO:0051059]; Notch binding [GO:0005112]; oxygen sensor activity [GO:0019826]; peptidyl-asparagine 3-dioxygenase activity [GO:0036140]; peptidyl-histidine dioxygenase activity [GO:0036139]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]
d3pvjd__d4cwda2__1		Metazoa	Proteobacteria	Chordata	dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]; carnitine biosynthetic process [GO:0045329]		carnitine biosynthetic process [GO:0045329]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]	gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]
d3pvnb__d2a3xa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d3pvnb__d3ap4d___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d3pvnf__d5jrma___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	endo-1,4-beta-xylanase activity [GO:0031176]
d3pvni__d5ik4a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	signaling receptor binding [GO:0005102]
d3pvnp__d2lal.2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]; carbohydrate mediated signaling [GO:0009756]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	carbohydrate mediated signaling [GO:0009756]	extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]
d3pvns__d1lgc.2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3pvns__d3kqre___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d3pvoa__d2a3wt___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d3pvob__d1qf3d___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3pvoc__d1fayh___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3pvoi__d5jp5e___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cytoplasm [GO:0005737]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; lymphatic endothelial cell migration [GO:1904977]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	lymphatic endothelial cell migration [GO:1904977]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d3pvoj__d3ayab1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]
d3pvol__d5ocqb1__1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	periplasmic space [GO:0042597]; kappa-carrageenase activity [GO:0033918]; carbohydrate metabolic process [GO:0005975]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	periplasmic space [GO:0042597]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	kappa-carrageenase activity [GO:0033918]
d3pvom__d4ayub___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d3pvop__d1valb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3pvos__d2a3wa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d3pvos__d4xtpa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3pvot__d4crqb___1	Metazoa		Chordata	Bacteroidetes	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; extracellular space [GO:0005615]		calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]
d3pvrb1_d1xvbb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	phenylacetate catabolic process [GO:0010124]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3pvua1_d5he1a1__1	Metazoa	Metazoa	Chordata	Chordata	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]; alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]; cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of catecholamine secretion [GO:0033605]; receptor internalization [GO:0031623]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of catecholamine secretion [GO:0033605]; receptor internalization [GO:0031623]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]	cilium [GO:0005929]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]	G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]	alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]
d3pvub__d3p4fa___1	Metazoa	Metazoa	Chordata	Chordata	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]; histone binding [GO:0042393]; methylated histone binding [GO:0035064]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; post-translational protein modification [GO:0043687]; regulation of megakaryocyte differentiation [GO:0045652]; skeletal system development [GO:0001501]	G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]	Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; histone acetyltransferase complex [GO:0000123]; histone methyltransferase complex [GO:0035097]; MLL1 complex [GO:0071339]; MLL3/4 complex [GO:0044666]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; Set1C/COMPASS complex [GO:0048188]	G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]	histone binding [GO:0042393]; methylated histone binding [GO:0035064]
d3pvwb__d4ul7g___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]; alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]; cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein phosphorylation [GO:0006468]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]		cardiac muscle contraction [GO:0060048]; desensitization of G protein-coupled receptor signaling pathway [GO:0002029]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled receptor internalization [GO:0002031]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; negative regulation of striated muscle contraction [GO:0045988]; negative regulation of the force of heart contraction by chemical signal [GO:0003108]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein phosphorylation [GO:0006468]; regulation of signal transduction [GO:0009966]; tachykinin receptor signaling pathway [GO:0007217]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; synapse [GO:0045202]		alpha-2A adrenergic receptor binding [GO:0031694]; ATP binding [GO:0005524]; beta-adrenergic receptor kinase activity [GO:0047696]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; G protein-coupled receptor kinase activity [GO:0004703]; protein kinase activity [GO:0004672]	
d3pvyb1_d1xu5d___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	phenylacetate catabolic process [GO:0010124]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3pvyc1_d5d8yh___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	phenylacetate catabolic process [GO:0010124]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cytosol [GO:0005829]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3pw8a__d1fz1d___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	phenylacetate catabolic process [GO:0010124]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3pw8a__d2bjye___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	phenylacetate catabolic process [GO:0010124]	cellular iron ion homeostasis [GO:0006879]	cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3pw8b__d1t0rb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	phenylacetate catabolic process [GO:0010124]	cellular aromatic compound metabolic process [GO:0006725]	cytosol [GO:0005829]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d3pwea2_d1rwza2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]		3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d3pwea2_d4cs5a2__1		Metazoa	Proteobacteria	Arthropoda	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	nucleus [GO:0005634]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d3pwfa1_d4u3gi___1			Euryarchaeota	Proteobacteria	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3pwga2_d2chra1__1			Proteobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]	D-glucarate catabolic process [GO:0042838]	aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]			glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d3pwgb1_d2ggee2__1			Proteobacteria	Firmicutes	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	D-glucarate catabolic process [GO:0042838]				glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3pwgd2_d4hchb2__1			Proteobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	D-glucarate catabolic process [GO:0042838]				glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3pwib1_d2gged2__1			Proteobacteria	Firmicutes	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	D-glucarate catabolic process [GO:0042838]				glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3pwjb1_d6fabl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3pwlb1_d1igih1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3pwld2_d2gfbh2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3pwld2_d5mhrh1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3pwle1_d1c5cl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3pwma__d4ha5a___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3pwnb1_d1dzbb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3pwnd1_d3ta3a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3pwnd2_d4fqqe1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3pwpa2_d3cfjb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3pwqg1_d4gaml___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	phenylacetate catabolic process [GO:0010124]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]			metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3pwqi1_d2fjcp___1			Proteobacteria	Spirochaetes	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	phenylacetate catabolic process [GO:0010124]	cellular iron ion homeostasis [GO:0006879]	cytosol [GO:0005829]	cell [GO:0005623]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3pwqk__d2c41c___1			Proteobacteria	Cyanobacteria	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	phenylacetate catabolic process [GO:0010124]	cellular iron ion homeostasis [GO:0006879]	cytosol [GO:0005829]	cell [GO:0005623]		DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3pwqk__d3ge8d___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	phenylacetate catabolic process [GO:0010124]	toluene catabolic process [GO:0042203]	cytosol [GO:0005829]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d3pwsa2_d1t1ra4__1				Proteobacteria		1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]		isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process [GO:0051484]				1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [GO:0030604]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; NADPH binding [GO:0070402]
d3pwza1_d1hwxb3__1			Proteobacteria		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]				NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	
d3pxaa1_d3pc8d1__1	Metazoa	Metazoa	Chordata	Chordata	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; gamma-tubulin ring complex [GO:0008274]; lateral element [GO:0000800]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151]; androgen receptor binding [GO:0050681]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; androgen receptor signaling pathway [GO:0030521]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to indole-3-methanol [GO:0071681]; cellular response to tumor necrosis factor [GO:0071356]; centrosome cycle [GO:0007098]; chordate embryonic development [GO:0043009]; chromosome segregation [GO:0007059]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; fatty acid biosynthetic process [GO:0006633]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of centriole replication [GO:0046600]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of DNA repair [GO:0045739]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of histone H4-K20 methylation [GO:0070512]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; response to estrogen [GO:0043627]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; cerebellum morphogenesis [GO:0021587]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; voluntary musculoskeletal movement [GO:0050882]	androgen receptor signaling pathway [GO:0030521]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to indole-3-methanol [GO:0071681]; cellular response to tumor necrosis factor [GO:0071356]; centrosome cycle [GO:0007098]; chordate embryonic development [GO:0043009]; chromosome segregation [GO:0007059]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; fatty acid biosynthetic process [GO:0006633]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of centriole replication [GO:0046600]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of DNA repair [GO:0045739]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of histone H4-K20 methylation [GO:0070512]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; response to estrogen [GO:0043627]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	base-excision repair [GO:0006284]; cerebellum morphogenesis [GO:0021587]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; voluntary musculoskeletal movement [GO:0050882]	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; gamma-tubulin ring complex [GO:0008274]; lateral element [GO:0000800]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	androgen receptor binding [GO:0050681]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]
d3pxfa1_d5mqvb___1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; tau-protein kinase activity [GO:0050321]; ciliary basal body-plasma membrane docking [GO:0097711]; circadian regulation of gene expression [GO:0032922]; COPII vesicle coating [GO:0048208]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi organization [GO:0007030]; microtubule nucleation [GO:0007020]; non-motile cilium assembly [GO:1905515]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation [GO:1905426]; protein localization to centrosome [GO:0071539]; protein localization to cilium [GO:0061512]; protein localization to Golgi apparatus [GO:0034067]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	ciliary basal body-plasma membrane docking [GO:0097711]; circadian regulation of gene expression [GO:0032922]; COPII vesicle coating [GO:0048208]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi organization [GO:0007030]; microtubule nucleation [GO:0007020]; non-motile cilium assembly [GO:1905515]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation [GO:1905426]; protein localization to centrosome [GO:0071539]; protein localization to cilium [GO:0061512]; protein localization to Golgi apparatus [GO:0034067]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; spindle [GO:0005819]; spindle microtubule [GO:0005876]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; tau-protein kinase activity [GO:0050321]
d3pxja2_d5d7ib___1	Metazoa	Metazoa	Arthropoda	Chordata	axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3pxjb1_d3tvmf___1	Metazoa	Metazoa	Arthropoda	Chordata	axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	
d3pxjb2_d3tyfa1__1	Metazoa		Arthropoda		axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]		axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; centripetally migrating follicle cell migration [GO:0060269]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; peptidyl-tyrosine dephosphorylation [GO:0035335]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of plasma membrane bounded cell projection assembly [GO:0120034]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]		axon [GO:0030424]; basal plasma membrane [GO:0009925]; cell leading edge [GO:0031252]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]		heparin binding [GO:0008201]; protein tyrosine phosphatase activity [GO:0004725]; SAM domain binding [GO:0032093]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	
d3pxla1_d1id2a___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3pxla3_d2pp7c2__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3pxmb__d1nb3k___1	Viridiplantae	Metazoa	Streptophyta	Chordata		cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]; cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cell-cell adhesion [GO:0098609]; cornification [GO:0070268]; keratinocyte differentiation [GO:0030216]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; peptide cross-linking [GO:0018149]		cornified envelope [GO:0001533]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleoplasm [GO:0005654]		cysteine-type endopeptidase inhibitor activity [GO:0004869]; protease binding [GO:0002020]
d3pxmb__d2o9ux___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta								
d3pxsd__d1mg3e___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3py8a1_d2pzsd1__1			Deinococcus-Thermus		DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]			DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]
d3pyja__d4n6mb___1	Viridiplantae	Metazoa	Streptophyta	Chordata		cornified envelope [GO:0001533]; extracellular exosome [GO:0070062]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; anatomical structure morphogenesis [GO:0009653]; epidermis development [GO:0008544]		anatomical structure morphogenesis [GO:0009653]; epidermis development [GO:0008544]		cornified envelope [GO:0001533]; extracellular exosome [GO:0070062]		cysteine-type endopeptidase inhibitor activity [GO:0004869]
d3pylc2_d1nqao2__1				Firmicutes		cytoplasm [GO:0005737]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3pyld2_d1rm5o2__1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]		glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]		chloroplast [GO:0009507]		glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity [GO:0047100]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3pypa__d1xj2a___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	integral component of plasma membrane [GO:0005887]; ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; protein autophosphorylation [GO:0046777]; regulation of transcription, DNA-templated [GO:0006355]		integral component of plasma membrane [GO:0005887]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; histidine phosphotransfer kinase activity [GO:0009927]; metal ion binding [GO:0046872]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]
d3pz4b__d3cu7ae__1	Metazoa	Metazoa	Chordata	Chordata	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]; chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; cytolysis [GO:0019835]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; negative regulation of macrophage chemotaxis [GO:0010760]; positive regulation of angiogenesis [GO:0045766]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of complement activation [GO:0030449]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane attack complex [GO:0005579]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]	chemokine activity [GO:0008009]; endopeptidase inhibitor activity [GO:0004866]; signaling receptor binding [GO:0005102]
d3pz9a__d1jiba3__1			Thermotogae	Firmicutes	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			mannan endo-1,4-beta-mannosidase activity [GO:0016985]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d3pzba2_d3cina2__1				Thermotogae		inositol-3-phosphate synthase activity [GO:0004512]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]		inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]				inositol-3-phosphate synthase activity [GO:0004512]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d3pzga__d1jyzl5__1			Thermotogae		mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				mannan endo-1,4-beta-mannosidase activity [GO:0016985]	
d3pzia__d3t09b3__1			Thermotogae	Proteobacteria	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3pzma__d3wbea___1		Viridiplantae	Thermotogae	Streptophyta	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	mannan endo-1,4-beta-mannosidase activity [GO:0016985]	beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; scopolin beta-glucosidase activity [GO:0102483]
d3pzoa__d2x8rf___1		Fungi	Thermotogae	Ascomycota	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	carbohydrate metabolic process [GO:0005975]	cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]			mannan endo-1,4-beta-mannosidase activity [GO:0016985]	lysozyme activity [GO:0003796]
d3pzub__d4pmya___1			Firmicutes	Proteobacteria	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]
d3pzub__d5e0fa1__1		Metazoa	Firmicutes	Chordata	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	cellulose catabolic process [GO:0030245]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3pzvb__d3gxnb1__1		Metazoa	Firmicutes	Chordata	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cellulose catabolic process [GO:0030245]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d3pzvb__d4ee9a___1			Firmicutes		cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulase activity [GO:0008810]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	cellulase activity [GO:0008810]
d3pzwa2_d2iukb2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]; oxylipin biosynthetic process [GO:0031408]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; oxylipin biosynthetic process [GO:0031408]	oxylipin biosynthetic process [GO:0031408]	oxylipin biosynthetic process [GO:0031408]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	linoleate 13S-lipoxygenase activity [GO:0016165]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d3pzxa__d2qe7b2__1				Firmicutes		plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]		ATP synthesis coupled proton transport [GO:0015986]		plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3q0ea2_d1k3ta2__1			Proteobacteria		aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	glycosome [GO:0020015]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]		glycosome [GO:0020015]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [GO:0004365]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3q0eb2_d3q1la2__1			Proteobacteria	Firmicutes	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]; 'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; methionine biosynthetic process [GO:0009086]; threonine biosynthetic process [GO:0009088]	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]			aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]	aspartate-semialdehyde dehydrogenase activity [GO:0004073]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein dimerization activity [GO:0046983]
d3q0jc__d1yg8t___1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	fatty acid beta-oxidation [GO:0006635]	proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cell wall [GO:0005618]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3q0jf__d3k8xc1__1		Fungi	Actinobacteria	Ascomycota	cell wall [GO:0005618]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	fatty acid beta-oxidation [GO:0006635]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	cell wall [GO:0005618]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d3q0mb__d1m8wb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]
d3q0mb__d4yi0c___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]	histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]
d3q0na__d3bsxb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]
d3q0sa__d1xqsa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; regulation of translation [GO:0006417]; stress granule assembly [GO:0034063]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]; ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; regulation of translation [GO:0006417]; stress granule assembly [GO:0034063]	ATP metabolic process [GO:0046034]; cellular heat acclimation [GO:0070370]; cellular response to heat [GO:0034605]; cellular response to oxidative stress [GO:0034599]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein complex assembly [GO:0051131]; lysosomal transport [GO:0007041]; mRNA catabolic process [GO:0006402]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil degranulation [GO:0043312]; positive regulation of endoribonuclease activity [GO:1902380]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of microtubule nucleation [GO:0090063]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of RNA splicing [GO:0033120]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic spindle assembly [GO:1901673]; regulation of mRNA stability [GO:0043488]; regulation of protein ubiquitination [GO:0031396]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]	aggresome [GO:0016235]; blood microparticle [GO:0072562]; centriole [GO:0005814]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; inclusion body [GO:0016234]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; vesicle [GO:0031982]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; denatured protein binding [GO:0031249]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; protein N-terminus binding [GO:0047485]; RNA binding [GO:0003723]; signaling receptor binding [GO:0005102]; transcription corepressor activity [GO:0003714]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; virus receptor activity [GO:0001618]
d3q10b1_d2q1ia1__1			Proteobacteria		cytosol [GO:0005829]; ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]; pantothenate biosynthetic process from valine [GO:0033317]		pantothenate biosynthetic process from valine [GO:0033317]		cytosol [GO:0005829]		ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]	
d3q14a__d1mfrn___1		Metazoa	Proteobacteria	Chordata	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	toluene catabolic process [GO:0042203]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3q18a1_d1m0ub2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; prostaglandin-D synthase activity [GO:0004667]; glutathione metabolic process [GO:0006749]; response to oxidative stress [GO:0006979]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; prostaglandin-D synthase activity [GO:0004667]
d3q18b1_d1e6ba2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutathione transferase activity [GO:0004364]; maleylacetoacetate isomerase activity [GO:0016034]; peroxidase activity [GO:0004601]; aromatic amino acid family metabolic process [GO:0009072]; glutathione metabolic process [GO:0006749]; homogentisate catabolic process [GO:1902000]; toxin catabolic process [GO:0009407]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	aromatic amino acid family metabolic process [GO:0009072]; glutathione metabolic process [GO:0006749]; homogentisate catabolic process [GO:1902000]; toxin catabolic process [GO:0009407]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]	glutathione transferase activity [GO:0004364]; maleylacetoacetate isomerase activity [GO:0016034]; peroxidase activity [GO:0004601]
d3q18b2_d3vura2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]	transferase activity [GO:0016740]
d3q19a2_d3i6ah2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3q19b1_d3a2wf___1	Metazoa		Chordata	Crenarchaeota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytoplasm [GO:0005737]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d3q1tb__d2vx2d___1		Metazoa	Actinobacteria	Chordata	catalytic activity [GO:0003824]	mitochondrion [GO:0005739]; catalytic activity [GO:0003824]; fatty acid metabolic process [GO:0006631]		fatty acid metabolic process [GO:0006631]		mitochondrion [GO:0005739]	catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d3q1ya1_d4xdac___1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; tagatose-6-phosphate kinase activity [GO:0009024]; D-tagatose 6-phosphate catabolic process [GO:2001059]; lactose metabolic process [GO:0005988]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]	D-tagatose 6-phosphate catabolic process [GO:2001059]; lactose metabolic process [GO:0005988]	D-ribose catabolic process [GO:0019303]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; tagatose-6-phosphate kinase activity [GO:0009024]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d3q20b__d4gr2b___1		Viridiplantae	Cyanobacteria	Streptophyta		chloroplast thylakoid [GO:0009534]; protein folding chaperone [GO:0044183]; chaperone-mediated protein folding [GO:0061077]; response to cold [GO:0009409]; response to salt stress [GO:0009651]; response to water deprivation [GO:0009414]		chaperone-mediated protein folding [GO:0061077]; response to cold [GO:0009409]; response to salt stress [GO:0009651]; response to water deprivation [GO:0009414]		chloroplast thylakoid [GO:0009534]		protein folding chaperone [GO:0044183]
d3q28a__d3rtff___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3q29a__d5otca___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]; ligand-gated ion channel activity [GO:0015276]; nitrogen compound transport [GO:0071705]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	nitrogen compound transport [GO:0071705]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	membrane [GO:0016020]; outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	ligand-gated ion channel activity [GO:0015276]
d3q29a__d5wnna___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; phosphate ion binding [GO:0042301]; phosphate ion transmembrane transport [GO:0035435]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	phosphate ion transmembrane transport [GO:0035435]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	phosphate ion binding [GO:0042301]
d3q2aa__d3n3aa___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	toluene catabolic process [GO:0042203]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3q2ac__d3n1yc___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d3q2ae__d1ckva___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	monooxygenase activity [GO:0004497]
d3q2ea__d5pbfa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin organization [GO:0006325]; cytoskeleton organization [GO:0007010]; interleukin-7-mediated signaling pathway [GO:0038111]; regulation of cell shape [GO:0008360]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	chromatin organization [GO:0006325]; cytoskeleton organization [GO:0007010]; interleukin-7-mediated signaling pathway [GO:0038111]; regulation of cell shape [GO:0008360]; regulation of transcription by RNA polymerase II [GO:0006357]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleus [GO:0005634]		DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d3q2fa1_d5ii1a___1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	nucleus [GO:0005634]	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]
d3q2la1_d4zmtd2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3q2lb1_d4zmwb2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3q2lb2_d4zmxb2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3q2na1_d4zmte2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3q2na2_d4zmxa2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3q2nb1_d4zmvb2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3q2sd__d1wwhd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]; exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]; messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	nuclear lamina [GO:0005652]; nuclear membrane [GO:0031965]; nuclear pore central transport channel [GO:0044613]; nuclear pore nuclear basket [GO:0044615]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; single-stranded DNA binding [GO:0003697]; structural constituent of nuclear pore [GO:0017056]; cellular response to leukemia inhibitory factor [GO:1990830]; mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore organization [GO:0006999]	messenger ribonucleoprotein complex assembly [GO:1990120]; mRNA alternative polyadenylation [GO:0110104]; mRNA processing [GO:0006397]; positive regulation of RNA export from nucleus [GO:0046833]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]	cellular response to leukemia inhibitory factor [GO:1990830]; mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore organization [GO:0006999]	cytoplasm [GO:0005737]; interchromatin granule [GO:0035061]; membrane [GO:0016020]; mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; mRNA cleavage factor complex [GO:0005849]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; paraspeckles [GO:0042382]; perichromatin fibrils [GO:0005726]; ribonucleoprotein complex [GO:1990904]	nuclear lamina [GO:0005652]; nuclear membrane [GO:0031965]; nuclear pore central transport channel [GO:0044613]; nuclear pore nuclear basket [GO:0044615]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	exon-exon junction complex binding [GO:1990448]; mRNA binding [GO:0003729]; ribosomal large subunit binding [GO:0043023]; RNA binding [GO:0003723]	phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; single-stranded DNA binding [GO:0003697]; structural constituent of nuclear pore [GO:0017056]
d3q37c__d2y63a___1					cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d3q3gc1_d3gsnh2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3q3ge__d5thpf___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	axon terminus [GO:0043679]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha2-beta1 complex [GO:0034666]; integrin complex [GO:0008305]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; collagen receptor activity [GO:0038064]; heparan sulfate proteoglycan binding [GO:0043395]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; virus receptor activity [GO:0001618]; animal organ morphogenesis [GO:0009887]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell population proliferation [GO:0008283]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; collagen-activated signaling pathway [GO:0038065]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; focal adhesion assembly [GO:0048041]; hepatocyte differentiation [GO:0070365]; hypotonic response [GO:0006971]; integrin-mediated signaling pathway [GO:0007229]; mammary gland development [GO:0030879]; mesodermal cell differentiation [GO:0048333]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell projection organization [GO:0031346]; positive regulation of collagen binding [GO:0033343]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of translation [GO:0045727]; positive regulation of transmission of nerve impulse [GO:0051971]; response to amine [GO:0014075]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to L-ascorbic acid [GO:0033591]; response to muscle activity [GO:0014850]; response to parathyroid hormone [GO:0071107]; skin morphogenesis [GO:0043589]; substrate-dependent cell migration [GO:0006929]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	animal organ morphogenesis [GO:0009887]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell population proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; collagen-activated signaling pathway [GO:0038065]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; focal adhesion assembly [GO:0048041]; hepatocyte differentiation [GO:0070365]; hypotonic response [GO:0006971]; integrin-mediated signaling pathway [GO:0007229]; mammary gland development [GO:0030879]; mesodermal cell differentiation [GO:0048333]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell projection organization [GO:0031346]; positive regulation of collagen binding [GO:0033343]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of translation [GO:0045727]; positive regulation of transmission of nerve impulse [GO:0051971]; response to amine [GO:0014075]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to L-ascorbic acid [GO:0033591]; response to muscle activity [GO:0014850]; response to parathyroid hormone [GO:0071107]; skin morphogenesis [GO:0043589]; substrate-dependent cell migration [GO:0006929]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	axon terminus [GO:0043679]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha2-beta1 complex [GO:0034666]; integrin complex [GO:0008305]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	amyloid-beta binding [GO:0001540]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; collagen receptor activity [GO:0038064]; heparan sulfate proteoglycan binding [GO:0043395]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; virus receptor activity [GO:0001618]
d3q3gf1_d1bvla1__1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	
d3q3gf1_d4xp9l1__1	Metazoa	Metazoa	Chordata	Arthropoda	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]; adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	integral component of plasma membrane [GO:0005887]; neuronal cell body membrane [GO:0032809]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]
d3q3gf2_d2xa3a___1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	
d3q3gi__d1idoa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]
d3q3ma__d2jd86___1			Proteobacteria	Euryarchaeota	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	toluene catabolic process [GO:0042203]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	ferric iron binding [GO:0008199]
d3q3na__d1data___1		Metazoa	Proteobacteria	Chordata	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	toluene catabolic process [GO:0042203]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3q3oa__d5vtda___1		Metazoa	Proteobacteria	Chordata	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	toluene catabolic process [GO:0042203]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]		autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3q3ya1_d1tx6b___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; digestion [GO:0007586]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular space [GO:0005615]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3q40a__d1suea___1	Fungi		Ascomycota	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		fibrinolysis [GO:0042730]; proteolysis [GO:0006508]; sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3q45c1_d1wuea2__1			Bacteroidetes	Firmicutes	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	peptide metabolic process [GO:0006518]	menaquinone biosynthetic process [GO:0009234]			magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3q45c2_d1xs2a1__1			Bacteroidetes	Deinococcus-Thermus	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	peptide metabolic process [GO:0006518]	menaquinone biosynthetic process [GO:0009234]			magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3q45e1_d2ggeg2__1			Bacteroidetes	Firmicutes	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	peptide metabolic process [GO:0006518]				magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3q45f2_d2mnra1__1			Bacteroidetes	Proteobacteria	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	peptide metabolic process [GO:0006518]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d3q45g2_d3uxkc2__1			Bacteroidetes	Proteobacteria	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	peptide metabolic process [GO:0006518]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]			magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d3q45h2_d4za0b2__1		Metazoa	Bacteroidetes	Chordata	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	peptide metabolic process [GO:0006518]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3q45i1_d4il2d1__1			Bacteroidetes	Proteobacteria	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	peptide metabolic process [GO:0006518]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d3q4bb__d2uxzb___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3q4da1_d2p8ca1__1			Bacteroidetes	Firmicutes	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]; peptide metabolic process [GO:0006518]	peptide metabolic process [GO:0006518]	peptide metabolic process [GO:0006518]			magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]
d3q4dc1_d4e4fa1__1			Bacteroidetes	Proteobacteria	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	peptide metabolic process [GO:0006518]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d3q4dc2_d3ujfa2__1		Metazoa	Bacteroidetes	Chordata	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	peptide metabolic process [GO:0006518]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3q4dd1_d1sjcb2__1			Bacteroidetes	Actinobacteria	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	peptide metabolic process [GO:0006518]	menaquinone biosynthetic process [GO:0009234]			magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3q4dd2_d2rdxb2__1			Bacteroidetes	Proteobacteria	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	metal ion binding [GO:0046872]	peptide metabolic process [GO:0006518]				magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	metal ion binding [GO:0046872]
d3q4df1_d4e6mg1__1			Bacteroidetes	Proteobacteria	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	metal ion binding [GO:0046872]	peptide metabolic process [GO:0006518]				magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	metal ion binding [GO:0046872]
d3q4df2_d3pwga2__1			Bacteroidetes	Proteobacteria	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	peptide metabolic process [GO:0006518]	D-glucarate catabolic process [GO:0042838]			magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3q4uc__d5nqca___1	Metazoa	Metazoa	Chordata	Chordata	activin receptor complex [GO:0048179]; apical part of cell [GO:0045177]; BMP receptor complex [GO:0070724]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; activin binding [GO:0048185]; activin receptor activity, type I [GO:0016361]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; metal ion binding [GO:0046872]; peptide hormone binding [GO:0017046]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase binding [GO:1990782]; SMAD binding [GO:0046332]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]; activin receptor signaling pathway [GO:0032924]; acute inflammatory response [GO:0002526]; angiogenesis [GO:0001525]; atrial septum primum morphogenesis [GO:0003289]; atrioventricular valve morphogenesis [GO:0003181]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac muscle cell fate commitment [GO:0060923]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; determination of left/right symmetry [GO:0007368]; embryonic heart tube morphogenesis [GO:0003143]; endocardial cushion cell fate commitment [GO:0061445]; endocardial cushion fusion [GO:0003274]; endocardial cushion morphogenesis [GO:0003203]; G1/S transition of mitotic cell cycle [GO:0000082]; gastrulation with mouth forming second [GO:0001702]; germ cell development [GO:0007281]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of signal transduction [GO:0009968]; neural crest cell migration [GO:0001755]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell migration [GO:0030335]; positive regulation of determination of dorsal identity [GO:2000017]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]; regulation of ossification [GO:0030278]; smooth muscle cell differentiation [GO:0051145]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular septum morphogenesis [GO:0060412]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]; ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	activin receptor signaling pathway [GO:0032924]; acute inflammatory response [GO:0002526]; angiogenesis [GO:0001525]; atrial septum primum morphogenesis [GO:0003289]; atrioventricular valve morphogenesis [GO:0003181]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac muscle cell fate commitment [GO:0060923]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; determination of left/right symmetry [GO:0007368]; embryonic heart tube morphogenesis [GO:0003143]; endocardial cushion cell fate commitment [GO:0061445]; endocardial cushion fusion [GO:0003274]; endocardial cushion morphogenesis [GO:0003203]; G1/S transition of mitotic cell cycle [GO:0000082]; gastrulation with mouth forming second [GO:0001702]; germ cell development [GO:0007281]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of signal transduction [GO:0009968]; neural crest cell migration [GO:0001755]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell migration [GO:0030335]; positive regulation of determination of dorsal identity [GO:2000017]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of ossification [GO:0030278]; smooth muscle cell differentiation [GO:0051145]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular septum morphogenesis [GO:0060412]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	activin receptor complex [GO:0048179]; apical part of cell [GO:0045177]; BMP receptor complex [GO:0070724]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]	activin binding [GO:0048185]; activin receptor activity, type I [GO:0016361]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; metal ion binding [GO:0046872]; peptide hormone binding [GO:0017046]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase binding [GO:1990782]; SMAD binding [GO:0046332]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity, type I [GO:0005025]; transmembrane receptor protein serine/threonine kinase activity [GO:0004675]	ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]
d3q5fa__d1v4ra1__1			Proteobacteria	Actinobacteria	DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	pathogenesis [GO:0009405]; regulation of transcription, DNA-templated [GO:0006355]				DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3q5ga__d1wmda2__1	Fungi		Ascomycota	Firmicutes	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]					metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3q5ha__d5conb___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]		aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]
d3q5ld1_d2ye4a___1		Metazoa		Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3q5oa1_d5m2ij___1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d3q5ob1_d3qiua2__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	
d3q5ta2_d1e4wl1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3q5vb__d2uxsc1__1			Euryarchaeota	Actinobacteria	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3q5ya1_d1ao7a1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3q5ya2_d4y16b___1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d3q5yb1_d1u3hg1__1		Metazoa		Chordata		T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]		T cell receptor complex [GO:0042101]		
d3q5yb2_d2bsub2__1												
d3q5yc1_d1brec___1												
d3q5yc2_d4p3cl2__1		Metazoa		Chordata		cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; intermediate filament cytoskeleton [GO:0045111]; macropinosome [GO:0044354]; melanosome [GO:0042470]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; metalloaminopeptidase activity [GO:0070006]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; astrocyte cell migration [GO:0043615]; branching morphogenesis of an epithelial tube [GO:0048754]; cell motility [GO:0048870]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; endodermal cell differentiation [GO:0035987]; endothelial cell proliferation [GO:0001935]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; head development [GO:0060322]; lung development [GO:0030324]; male gonad development [GO:0008584]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle development [GO:0001541]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of macrophage migration [GO:1905523]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein processing [GO:0010954]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein localization to plasma membrane [GO:1903076]; response to estrogen [GO:0043627]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to odorant [GO:1990834]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; skeletal system development [GO:0001501]; tissue remodeling [GO:0048771]; zymogen activation [GO:0031638]		angiogenesis [GO:0001525]; astrocyte cell migration [GO:0043615]; branching morphogenesis of an epithelial tube [GO:0048754]; cell motility [GO:0048870]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; endodermal cell differentiation [GO:0035987]; endothelial cell proliferation [GO:0001935]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; head development [GO:0060322]; lung development [GO:0030324]; male gonad development [GO:0008584]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle development [GO:0001541]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of macrophage migration [GO:1905523]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of protein processing [GO:0010954]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein localization to plasma membrane [GO:1903076]; response to estrogen [GO:0043627]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to odorant [GO:1990834]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; skeletal system development [GO:0001501]; tissue remodeling [GO:0048771]; zymogen activation [GO:0031638]		cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; integral component of plasma membrane [GO:0005887]; intermediate filament cytoskeleton [GO:0045111]; macropinosome [GO:0044354]; melanosome [GO:0042470]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		endopeptidase activity [GO:0004175]; integrin binding [GO:0005178]; metalloaminopeptidase activity [GO:0070006]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d3q62b1_d1bvqa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; fatty acid biosynthetic process [GO:0006633]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]
d3q67a__d3bv7a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	cytosol [GO:0005829]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]
d3q6fa1_d5sx5k2__1		Metazoa		Chordata		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d3q6fc2_d2hmid1__1						host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3q6fe1_d4k3hg___1												
d3q6fe2_d2akrd___1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3q6fg1_d1mcea1__1												
d3q6gl2_d3qzwg___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3q6gm1_d1v7ml1__1		Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]; cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]		cell population proliferation [GO:0008283]; megakaryocyte development [GO:0035855]; multicellular organism development [GO:0007275]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; receptor signaling pathway via STAT [GO:0097696]; thrombopoietin-mediated signaling pathway [GO:0038163]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; hormone activity [GO:0005179]; signaling receptor binding [GO:0005102]
d3q6gm2_d1f11b1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3q6xb__d2fu8b___1				Proteobacteria		periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d3q74a1_d1oe8b2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	glutathione transferase activity [GO:0004364]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d3q74a1_d4q5qa1__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	glutathione transferase activity [GO:0004364]
d3q74a2_d4gsna2__1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	transferase activity [GO:0016740]
d3q76a__d1befa___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; phagocytic vesicle [GO:0045335]; secretory granule [GO:0030141]; specific granule lumen [GO:0035580]; transcriptional repressor complex [GO:0017053]; cytokine binding [GO:0019955]; endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; transcription corepressor activity [GO:0003714]; acute inflammatory response to antigenic stimulus [GO:0002438]; antimicrobial humoral response [GO:0019730]; biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0002812]; cellular calcium ion homeostasis [GO:0006874]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of chemotaxis [GO:0050922]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of fungus [GO:0070947]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of immune response [GO:0050778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; response to UV [GO:0009411]; response to yeast [GO:0001878]		acute inflammatory response to antigenic stimulus [GO:0002438]; antimicrobial humoral response [GO:0019730]; biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0002812]; cellular calcium ion homeostasis [GO:0006874]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of chemotaxis [GO:0050922]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of fungus [GO:0070947]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of immune response [GO:0050778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; response to UV [GO:0009411]; response to yeast [GO:0001878]		azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; phagocytic vesicle [GO:0045335]; secretory granule [GO:0030141]; specific granule lumen [GO:0035580]; transcriptional repressor complex [GO:0017053]		cytokine binding [GO:0019955]; endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; transcription corepressor activity [GO:0003714]	
d3q76a__d1oyqa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; phagocytic vesicle [GO:0045335]; secretory granule [GO:0030141]; specific granule lumen [GO:0035580]; transcriptional repressor complex [GO:0017053]; cytokine binding [GO:0019955]; endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; transcription corepressor activity [GO:0003714]; acute inflammatory response to antigenic stimulus [GO:0002438]; antimicrobial humoral response [GO:0019730]; biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0002812]; cellular calcium ion homeostasis [GO:0006874]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of chemotaxis [GO:0050922]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of fungus [GO:0070947]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of immune response [GO:0050778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; response to UV [GO:0009411]; response to yeast [GO:0001878]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	acute inflammatory response to antigenic stimulus [GO:0002438]; antimicrobial humoral response [GO:0019730]; biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0002812]; cellular calcium ion homeostasis [GO:0006874]; defense response to bacterium [GO:0042742]; extracellular matrix disassembly [GO:0022617]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of chemotaxis [GO:0050922]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neutrophil degranulation [GO:0043312]; neutrophil mediated killing of fungus [GO:0070947]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of immune response [GO:0050778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to lipopolysaccharide [GO:0032496]; response to UV [GO:0009411]; response to yeast [GO:0001878]	digestion [GO:0007586]; proteolysis [GO:0006508]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; phagocytic vesicle [GO:0045335]; secretory granule [GO:0030141]; specific granule lumen [GO:0035580]; transcriptional repressor complex [GO:0017053]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytokine binding [GO:0019955]; endopeptidase activity [GO:0004175]; heparin binding [GO:0008201]; peptidase activity [GO:0008233]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; transcription corepressor activity [GO:0003714]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3q7ga__d3nyla___1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; alpha-2A adrenergic receptor binding [GO:0031694]; alpha-2B adrenergic receptor binding [GO:0031695]; alpha-2C adrenergic receptor binding [GO:0031696]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cellular response to norepinephrine stimulus [GO:0071874]; endocytosis [GO:0006897]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; nervous system development [GO:0007399]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cellular response to norepinephrine stimulus [GO:0071874]; endocytosis [GO:0006897]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; nervous system development [GO:0007399]	activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid-beta clearance [GO:1900221]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	basement membrane [GO:0005604]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi lumen [GO:0005796]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]	alpha-2A adrenergic receptor binding [GO:0031694]; alpha-2B adrenergic receptor binding [GO:0031695]; alpha-2C adrenergic receptor binding [GO:0031696]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]	acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]
d3q7ja4_d4bqkb___1		Viridiplantae	Euryarchaeota	Streptophyta	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	cytosol [GO:0005829]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; NLS-bearing protein import into nucleus [GO:0006607]; viral process [GO:0016032]		NLS-bearing protein import into nucleus [GO:0006607]; viral process [GO:0016032]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]	aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]
d3q83a__d3ztrc___1			Firmicutes	Aquificae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3q83e__d3fbee1__1			Firmicutes		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3q83e__d4anda___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]
d3q83f__d3b6bc1__1			Firmicutes		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3q86a__d3ztsg___1			Firmicutes	Aquificae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3q89c__d3ztrh___1			Firmicutes	Aquificae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3q8ga2_d1olme3__1	Fungi	Metazoa	Ascomycota	Chordata	nucleus [GO:0005634]; phosphatidylcholine binding [GO:0031210]; phosphatidylinositol binding [GO:0035091]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; phospholipid binding [GO:0005543]; vitamin E binding [GO:0008431]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cholesterol biosynthetic process [GO:0045540]		positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cholesterol biosynthetic process [GO:0045540]	nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	phosphatidylcholine binding [GO:0031210]; phosphatidylinositol binding [GO:0035091]	phospholipid binding [GO:0005543]; vitamin E binding [GO:0008431]
d3q8nb__d3imza___1			Actinobacteria		4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; pyridoxal phosphate binding [GO:0030170]; gamma-aminobutyric acid metabolic process [GO:0009448]		gamma-aminobutyric acid metabolic process [GO:0009448]				4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; pyridoxal phosphate binding [GO:0030170]	
d3q8ua__d3bbcc___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; G-quadruplex DNA binding [GO:0051880]; GDP binding [GO:0019003]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cell adhesion [GO:0007155]; cellular response to fatty acid [GO:0071398]; cellular response to glucose stimulus [GO:0071333]; cellular response to oxidative stress [GO:0034599]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of apoptotic process [GO:0043066]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; neutrophil degranulation [GO:0043312]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autophosphorylation [GO:0046777]; protein complex oligomerization [GO:0051259]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of epidermis development [GO:0045682]; response to growth hormone [GO:0060416]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intermediate filament [GO:0005882]; lamellipodium [GO:0030027]; mitochondrial membrane [GO:0031966]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; fatty acid binding [GO:0005504]; GDP binding [GO:0019003]; G-quadruplex DNA binding [GO:0051880]; intermediate filament binding [GO:0019215]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; protein histidine kinase activity [GO:0004673]; protein serine/threonine kinase activity [GO:0004674]; transcription coactivator activity [GO:0003713]
d3q8ua__d4f4aa___1			Firmicutes		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; posttranscriptional regulation of gene expression [GO:0010608]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; posttranscriptional regulation of gene expression [GO:0010608]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3q8ub__d5v6dh___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3q8vd__d3gpad1__1			Firmicutes		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3q8xb__d2ofwb___1		Metazoa	Firmicutes	Chordata	toxic substance binding [GO:0015643]; negative regulation of cell killing [GO:0031342]; response to toxic substance [GO:0009636]	cytosol [GO:0005829]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]	negative regulation of cell killing [GO:0031342]; response to toxic substance [GO:0009636]	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; skeletal system development [GO:0001501]; sulfate assimilation [GO:0000103]		cytosol [GO:0005829]	toxic substance binding [GO:0015643]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; protein homodimerization activity [GO:0042803]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d3q8yb__d4fkyc___1			Firmicutes		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; posttranscriptional regulation of gene expression [GO:0010608]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; posttranscriptional regulation of gene expression [GO:0010608]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3q8yd__d2az1a1__1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3q8yd__d3ztpc___1			Firmicutes	Aquificae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3q8yf__d2az1c___1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3q8yf__d4s0mi___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3q8yg__d3js9b___1			Firmicutes	Apicomplexa	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	nucleoside diphosphate kinase activity [GO:0004550]
d3q8yh__d2hurc___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3q9ba__d3hiwb___1		Viridiplantae	Proteobacteria	Streptophyta	acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]			acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3q9bb__d3q9ek___1			Proteobacteria	Proteobacteria	acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]					acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]
d3q9bc__d4z8sa___1		Viridiplantae	Proteobacteria	Streptophyta	acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]			acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3q9bh__d4kwna___1		Viridiplantae	Proteobacteria	Streptophyta	acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]			acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3q9ch__d3mena1__1			Proteobacteria	Proteobacteria	acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	acetylputrescine deacetylase activity [GO:0047609]; metal ion binding [GO:0046872]					acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	acetylputrescine deacetylase activity [GO:0047609]; metal ion binding [GO:0046872]
d3q9ck__d3v2ka___1		Viridiplantae	Proteobacteria	Streptophyta	acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]			acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3q9fg__d3q9ef___1			Proteobacteria	Proteobacteria	acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]					acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]	acetylputrescine deacetylase activity [GO:0047609]; acetylspermidine deacetylase activity [GO:0047611]; metal ion binding [GO:0046872]
d3q9nc__d4tumd___1		Viridiplantae		Streptophyta		chloroplast outer membrane [GO:0009707]; cytoplasm [GO:0005737]; integral component of chloroplast outer membrane [GO:0031359]; nucleus [GO:0005634]; chloroplast targeting sequence binding [GO:0030941]; glycolipid binding [GO:0051861]; protein targeting to chloroplast [GO:0045036]		protein targeting to chloroplast [GO:0045036]		chloroplast outer membrane [GO:0009707]; cytoplasm [GO:0005737]; integral component of chloroplast outer membrane [GO:0031359]; nucleus [GO:0005634]		chloroplast targeting sequence binding [GO:0030941]; glycolipid binding [GO:0051861]
d3q9uc__d2myoa___1		Metazoa		Chordata		axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; F-actin capping protein complex [GO:0008290]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sequence-specific DNA binding [GO:0043565]; catecholamine metabolic process [GO:0006584]; cellular response to mechanical stimulus [GO:0071260]; cerebellar granule cell differentiation [GO:0021707]; neuron differentiation [GO:0030182]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell growth [GO:0030307]; positive regulation of macromolecule biosynthetic process [GO:0010557]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein metabolic process [GO:0051247]; regulation of barbed-end actin filament capping [GO:2000812]; regulation of cell size [GO:0008361]; skeletal muscle tissue regeneration [GO:0043403]; striated muscle cell differentiation [GO:0051146]		catecholamine metabolic process [GO:0006584]; cellular response to mechanical stimulus [GO:0071260]; cerebellar granule cell differentiation [GO:0021707]; neuron differentiation [GO:0030182]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell growth [GO:0030307]; positive regulation of macromolecule biosynthetic process [GO:0010557]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein metabolic process [GO:0051247]; regulation of barbed-end actin filament capping [GO:2000812]; regulation of cell size [GO:0008361]; skeletal muscle tissue regeneration [GO:0043403]; striated muscle cell differentiation [GO:0051146]		axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; F-actin capping protein complex [GO:0008290]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]		sequence-specific DNA binding [GO:0043565]
d3q9uc__d3twvb___1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]		multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]		enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]
d3qa0a__d5e90a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]; ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]; apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	activin receptor complex [GO:0048179]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell surface [GO:0009986]; endosome [GO:0005768]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; activin binding [GO:0048185]; activin receptor activity, type I [GO:0016361]; ATP binding [GO:0005524]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity, type I [GO:0005025]; transforming growth factor beta-activated receptor activity [GO:0005024]; type II transforming growth factor beta receptor binding [GO:0005114]; activation of MAPKK activity [GO:0000186]; activin receptor signaling pathway [GO:0032924]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; epicardium morphogenesis [GO:1905223]; epithelial to mesenchymal transition [GO:0001837]; extracellular structure organization [GO:0043062]; germ cell migration [GO:0008354]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; protein deubiquitination [GO:0016579]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; regulation of transcription, DNA-templated [GO:0006355]; response to cholesterol [GO:0070723]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060]	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chaperone-mediated protein folding [GO:0061077]; macroautophagy [GO:0016236]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein folding [GO:0006457]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of chromosome separation [GO:1905818]; regulation of signal transduction by p53 class mediator [GO:1901796]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	activation of MAPKK activity [GO:0000186]; activin receptor signaling pathway [GO:0032924]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; epicardium morphogenesis [GO:1905223]; epithelial to mesenchymal transition [GO:0001837]; extracellular structure organization [GO:0043062]; germ cell migration [GO:0008354]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; protein deubiquitination [GO:0016579]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; regulation of transcription, DNA-templated [GO:0006355]; response to cholesterol [GO:0070723]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; NuRD complex [GO:0016581]; plasma membrane [GO:0005886]; protein kinase CK2 complex [GO:0005956]; Sin3 complex [GO:0016580]	activin receptor complex [GO:0048179]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell surface [GO:0009986]; endosome [GO:0005768]; membrane [GO:0016020]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	ATP binding [GO:0005524]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; protein N-terminus binding [GO:0047485]; protein serine/threonine kinase activity [GO:0004674]	activin binding [GO:0048185]; activin receptor activity, type I [GO:0016361]; ATP binding [GO:0005524]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; SMAD binding [GO:0046332]; transforming growth factor beta-activated receptor activity [GO:0005024]; transforming growth factor beta binding [GO:0050431]; transforming growth factor beta receptor activity, type I [GO:0005025]; type II transforming growth factor beta receptor binding [GO:0005114]
d3qa3a1_d1t4kb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qa3c2_d2r1wb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qa3f1_d4llvh___1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	
d3qa3j1_d1nc2b2__1	Metazoa		Chordata		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		amyloid-beta clearance [GO:0097242]; apoptotic signaling pathway [GO:0097190]; cell adhesion [GO:0007155]; cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway involved in cell-cell signaling [GO:1905114]; complement-mediated synapse pruning [GO:0150062]; cytokine-mediated signaling pathway [GO:0019221]; ectodermal cell differentiation [GO:0010668]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; microglial cell activation [GO:0001774]; negative regulation of dopamine metabolic process [GO:0045963]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of hippocampal neuron apoptotic process [GO:0110090]; positive regulation of microglial cell mediated cytotoxicity [GO:1904151]; positive regulation of neuron death [GO:1901216]; positive regulation of neutrophil degranulation [GO:0043315]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of superoxide anion generation [GO:0032930]; receptor-mediated endocytosis [GO:0006898]; toll-like receptor 4 signaling pathway [GO:0034142]; vertebrate eye-specific patterning [GO:0150064]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integrin alphaM-beta2 complex [GO:0034688]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]		amyloid-beta binding [GO:0001540]; cargo receptor activity [GO:0038024]; complement component C3b binding [GO:0001851]; heat shock protein binding [GO:0031072]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]	
d3qaab__d5dr4a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3qaga1_d4xs1d___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; L-ascorbic acid metabolic process [GO:0019852]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell [GO:0005623]; cytosol [GO:0005829]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; identical protein binding [GO:0042802]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]	thioredoxin peroxidase activity [GO:0008379]
d3qajb1_d3zxre1__1				Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3qajc1_d1f1hf1__1				Proteobacteria		cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d3qajd1_d2glsf1__1				Proteobacteria		cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d3qajd2_d1htqf2__1				Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3qajf1_d1htqx1__1				Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3qajh1_d1fpyi1__1				Proteobacteria		cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d3qaji1_d1htql1__1				Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3qaji2_d2glse2__1				Proteobacteria		cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]		cytoplasm [GO:0005737]; membrane [GO:0016020]		ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d3qana1_d1nzzb___1		Metazoa	Firmicutes	Chordata	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3qanb1_d2onmf___1		Metazoa	Firmicutes	Chordata	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3qaxb1_d2owsa___1			Chlamydiae	Proteobacteria	cell surface [GO:0009986]; extracellular region [GO:0005576]; amino acid transport [GO:0006865]	metal ion binding [GO:0046872]	amino acid transport [GO:0006865]		cell surface [GO:0009986]; extracellular region [GO:0005576]			metal ion binding [GO:0046872]
d3qb6a__d2afih___1				Proteobacteria		molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d3qb6b__d4iokb___1				Firmicutes		ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; tetrahydrofolate interconversion [GO:0035999]		tetrahydrofolate interconversion [GO:0035999]				ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]
d3qb9d__d3oj5u___1			Actinobacteria	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3qb9e__d5jkmd___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3qb9f__d2c41c___1			Actinobacteria	Cyanobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3qbja2_d4x71a1__1	Metazoa		Chordata	Firmicutes	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d3qbjb2_d1iz8a___1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	periplasmic space [GO:0042597]; haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	response to toxic substance [GO:0009636]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	haloalkane dehalogenase activity [GO:0018786]
d3qbjb2_d3kwfb2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3qbqc__d1a8ma___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cytokine binding [GO:0019955]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]; tumor necrosis factor-activated receptor activity [GO:0005031]; adaptive immune response [GO:0002250]; circadian temperature homeostasis [GO:0060086]; lymph node development [GO:0048535]; mammary gland alveolus development [GO:0060749]; multicellular organism development [GO:0007275]; multinuclear osteoclast differentiation [GO:0072674]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of bone resorption [GO:0045780]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling [GO:0071848]; positive regulation of fever generation by positive regulation of prostaglandin secretion [GO:0071812]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; response to cytokine [GO:0034097]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to radiation [GO:0009314]; response to tumor necrosis factor [GO:0034612]; TNFSF11-mediated signaling pathway [GO:0071847]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	adaptive immune response [GO:0002250]; circadian temperature homeostasis [GO:0060086]; lymph node development [GO:0048535]; mammary gland alveolus development [GO:0060749]; multicellular organism development [GO:0007275]; multinuclear osteoclast differentiation [GO:0072674]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of bone resorption [GO:0045780]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling [GO:0071848]; positive regulation of fever generation by positive regulation of prostaglandin secretion [GO:0071812]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; response to cytokine [GO:0034097]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to radiation [GO:0009314]; response to tumor necrosis factor [GO:0034612]; TNFSF11-mediated signaling pathway [GO:0071847]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	cytokine binding [GO:0019955]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]; tumor necrosis factor-activated receptor activity [GO:0005031]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d3qbta__d5x9sa___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi stack [GO:0005795]; Golgi-associated vesicle [GO:0005798]; lysosome [GO:0005764]; membrane [GO:0016020]; nucleus [GO:0005634]; phagocytic vesicle membrane [GO:0030670]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; GTPase activator activity [GO:0005096]; inositol phosphate phosphatase activity [GO:0052745]; inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; Rac GTPase binding [GO:0048365]; cilium assembly [GO:0060271]; in utero embryonic development [GO:0001701]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; lipid metabolic process [GO:0006629]; membrane organization [GO:0061024]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cilium assembly [GO:0060271]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; lipid metabolic process [GO:0006629]; membrane organization [GO:0061024]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi-associated vesicle [GO:0005798]; Golgi stack [GO:0005795]; lysosome [GO:0005764]; membrane [GO:0016020]; nucleus [GO:0005634]; phagocytic vesicle membrane [GO:0030670]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	GTPase activator activity [GO:0005096]; inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol phosphate phosphatase activity [GO:0052745]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; Rac GTPase binding [GO:0048365]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d3qbtc__d2bekd___1	Metazoa		Chordata	Deinococcus-Thermus	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi stack [GO:0005795]; Golgi-associated vesicle [GO:0005798]; lysosome [GO:0005764]; membrane [GO:0016020]; nucleus [GO:0005634]; phagocytic vesicle membrane [GO:0030670]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; GTPase activator activity [GO:0005096]; inositol phosphate phosphatase activity [GO:0052745]; inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; Rac GTPase binding [GO:0048365]; cilium assembly [GO:0060271]; in utero embryonic development [GO:0001701]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; lipid metabolic process [GO:0006629]; membrane organization [GO:0061024]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]; chromosome segregation [GO:0007059]	cilium assembly [GO:0060271]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; lipid metabolic process [GO:0006629]; membrane organization [GO:0061024]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	chromosome segregation [GO:0007059]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi-associated vesicle [GO:0005798]; Golgi stack [GO:0005795]; lysosome [GO:0005764]; membrane [GO:0016020]; nucleus [GO:0005634]; phagocytic vesicle membrane [GO:0030670]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]		GTPase activator activity [GO:0005096]; inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity [GO:0052659]; inositol-1,4,5-trisphosphate 5-phosphatase activity [GO:0052658]; inositol phosphate phosphatase activity [GO:0052745]; inositol-polyphosphate 5-phosphatase activity [GO:0004445]; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [GO:0004439]; Rac GTPase binding [GO:0048365]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; hydrolase activity [GO:0016787]
d3qcaa__d1sgha3__1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]; beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	actin cytoskeleton organization [GO:0030036]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; auditory receptor cell stereocilium organization [GO:0060088]; bile acid secretion [GO:0032782]; cellular phosphate ion homeostasis [GO:0030643]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; gland morphogenesis [GO:0022612]; glutathione transport [GO:0034635]; microvillus assembly [GO:0030033]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sodium:proton antiporter activity [GO:0032416]; nuclear migration [GO:0007097]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of ion transmembrane transport [GO:0034767]; protein-containing complex assembly [GO:0065003]; protein localization to plasma membrane [GO:0072659]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of excretion [GO:0044062]; regulation of protein kinase activity [GO:0045859]; regulation of sodium:proton antiporter activity [GO:0032415]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; renal sodium ion transport [GO:0003096]; sensory perception of sound [GO:0007605]; Wnt signaling pathway [GO:0016055]	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]	actin cytoskeleton [GO:0015629]; apical plasma membrane [GO:0016324]; brush border membrane [GO:0031526]; cell [GO:0005623]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; filopodium [GO:0030175]; membrane [GO:0016020]; membrane raft [GO:0045121]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; sperm midpiece [GO:0097225]; stereocilium tip [GO:0032426]; vesicle [GO:0031982]	heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]	beta-2 adrenergic receptor binding [GO:0031698]; beta-catenin binding [GO:0008013]; chloride channel regulator activity [GO:0017081]; dopamine receptor binding [GO:0050780]; growth factor receptor binding [GO:0070851]; molecular adaptor activity [GO:0060090]; myosin II binding [GO:0045159]; PDZ domain binding [GO:0030165]; phosphatase binding [GO:0019902]; protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485]; protein self-association [GO:0043621]; signaling receptor binding [GO:0005102]
d3qcab__d1i42a___1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	cell [GO:0005623]; chromosome [GO:0005694]; cytosol [GO:0005829]; Golgi stack [GO:0005795]; intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; spindle pole centrosome [GO:0031616]; VCP-NSFL1C complex [GO:1990730]; ATPase binding [GO:0051117]; lipid binding [GO:0008289]; ubiquitin binding [GO:0043130]; autophagosome assembly [GO:0000045]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; negative regulation of protein localization to centrosome [GO:1904780]; nuclear envelope reassembly [GO:0031468]; positive regulation of mitotic centrosome separation [GO:0046604]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	autophagosome assembly [GO:0000045]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; negative regulation of protein localization to centrosome [GO:1904780]; nuclear envelope reassembly [GO:0031468]; positive regulation of mitotic centrosome separation [GO:0046604]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]	cell [GO:0005623]; chromosome [GO:0005694]; cytosol [GO:0005829]; Golgi stack [GO:0005795]; intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; spindle pole centrosome [GO:0031616]; VCP-NSFL1C complex [GO:1990730]	heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]	ATPase binding [GO:0051117]; lipid binding [GO:0008289]; ubiquitin binding [GO:0043130]
d3qcad__d2d11c3__1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	apical plasma membrane [GO:0016324]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]; protein-containing complex assembly [GO:0065003]	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	protein-containing complex assembly [GO:0065003]	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]	apical plasma membrane [GO:0016324]; endomembrane system [GO:0012505]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]	beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; protein C-terminus binding [GO:0008022]; signaling receptor binding [GO:0005102]
d3qctl1_d1a4kb2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qcul1_d1u8pa2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3qcum1_d4zykl2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3qcvl2_d1ymhb2__1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	pathogenesis [GO:0009405]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]
d3qcvm1_d4kroc2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d3qcvm2_d4ocyl1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	metal ion binding [GO:0046872]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	metal ion binding [GO:0046872]
d3qd8a__d5jkle___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3qd8b1_d5d8yf___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3qd8d1_d5czua___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3qd8f1_d1f33i___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3qd8g1_d4u3gj___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3qd8j1_d3a68p___1		Viridiplantae	Actinobacteria	Streptophyta	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3qd8j1_d3e1pk___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3qd8m1_d3a9qm___1		Viridiplantae	Actinobacteria	Streptophyta	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	flower development [GO:0009908]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; leaf development [GO:0048366]; photosynthesis [GO:0015979]; response to iron ion [GO:0010039]; response to reactive oxygen species [GO:0000302]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3qd8p1_d3h7ga___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3qd8q1_d3dhga___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	toluene catabolic process [GO:0042203]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d3qd8r1_d2chpb___1			Actinobacteria	Firmicutes	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3qd8u1_d5d8od___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3qd8w1_d2bjyk___1			Actinobacteria	Firmicutes	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3qd8w1_d2jd70___1			Actinobacteria	Euryarchaeota	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]
d3qdaa__d3kdml1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qdga2_d1pz5b1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qdgb1_d1q9ld1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qdge2_d5a16h1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qdja1_d1c16a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3qdjb1_d5u2vh1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3qdjd1_d4m6nl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qdjd1_d5t1dl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; carbohydrate binding [GO:0030246]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	viral process [GO:0016032]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]
d3qdjd2_d3wjlb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qdje1_d3bikb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of T cell apoptotic process [GO:0070234]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of T cell apoptotic process [GO:0070234]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qdmd1_d4at6p1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qdme1_d4w4ob2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qdme2_d2bx5l___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qdoa1_d1m5za___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; ionotropic glutamate receptor binding [GO:0035255]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3-phosphate binding [GO:0032266]; cellular response to nerve growth factor stimulus [GO:1990090]; endosomal transport [GO:0016197]; endosome to plasma membrane protein transport [GO:0099638]; establishment of protein localization to plasma membrane [GO:0061951]; intracellular protein transport [GO:0006886]; negative regulation of inward rectifier potassium channel activity [GO:1903609]; nervous system development [GO:0007399]; positive regulation of AMPA glutamate receptor clustering [GO:1904719]; response to methamphetamine hydrochloride [GO:1904313]; retrograde transport, endosome to plasma membrane [GO:1990126]; signal transduction [GO:0007165]	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; glucocorticoid receptor binding [GO:0035259]; receptor signaling complex adaptor activity [GO:0030159]; signaling receptor binding [GO:0005102]; dendrite development [GO:0016358]; nervous system development [GO:0007399]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection arborization [GO:0150012]; protein transport [GO:0015031]	cellular response to nerve growth factor stimulus [GO:1990090]; endosomal transport [GO:0016197]; endosome to plasma membrane protein transport [GO:0099638]; establishment of protein localization to plasma membrane [GO:0061951]; intracellular protein transport [GO:0006886]; negative regulation of inward rectifier potassium channel activity [GO:1903609]; nervous system development [GO:0007399]; positive regulation of AMPA glutamate receptor clustering [GO:1904719]; response to methamphetamine hydrochloride [GO:1904313]; retrograde transport, endosome to plasma membrane [GO:1990126]; signal transduction [GO:0007165]	dendrite development [GO:0016358]; nervous system development [GO:0007399]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of neuron projection arborization [GO:0150012]; protein transport [GO:0015031]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]	ionotropic glutamate receptor binding [GO:0035255]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol binding [GO:0035091]	glucocorticoid receptor binding [GO:0035259]; receptor signaling complex adaptor activity [GO:0030159]; signaling receptor binding [GO:0005102]
d3qdua__d1y2wb___1	Fungi	Fungi	Basidiomycota	Basidiomycota	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d3qdub__d2ks4a___1	Fungi	Metazoa	Basidiomycota	Cnidaria	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]	carbohydrate binding [GO:0030246]	channel activity [GO:0015267]; toxin activity [GO:0090729]
d3qdwa__d2l38a___1	Fungi	Metazoa	Basidiomycota	Cnidaria	carbohydrate binding [GO:0030246]	extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]; channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]; cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		cation transport [GO:0006812]; hemolysis in other organism involved in symbiotic interaction [GO:0052331]; pore complex assembly [GO:0046931]		extracellular region [GO:0005576]; nematocyst [GO:0042151]; other organism cell membrane [GO:0044218]; pore complex [GO:0046930]	carbohydrate binding [GO:0030246]	channel activity [GO:0015267]; identical protein binding [GO:0042802]; toxin activity [GO:0090729]
d3qdya__d2ks3a___1	Fungi		Basidiomycota		carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]	
d3qe1a1_d1ueza1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; ionotropic glutamate receptor binding [GO:0035255]; phosphatidylinositol binding [GO:0035091]; phosphatidylinositol-3-phosphate binding [GO:0032266]; cellular response to nerve growth factor stimulus [GO:1990090]; endosomal transport [GO:0016197]; endosome to plasma membrane protein transport [GO:0099638]; establishment of protein localization to plasma membrane [GO:0061951]; intracellular protein transport [GO:0006886]; negative regulation of inward rectifier potassium channel activity [GO:1903609]; nervous system development [GO:0007399]; positive regulation of AMPA glutamate receptor clustering [GO:1904719]; response to methamphetamine hydrochloride [GO:1904313]; retrograde transport, endosome to plasma membrane [GO:1990126]; signal transduction [GO:0007165]	actin filament [GO:0005884]; cell junction [GO:0030054]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; growth cone [GO:0030426]; periciliary membrane compartment [GO:1990075]; photoreceptor connecting cilium [GO:0032391]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; stereocilia ankle link [GO:0002141]; stereocilia ankle link complex [GO:0002142]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426]; synapse [GO:0045202]; USH2 complex [GO:1990696]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; auditory receptor cell stereocilium organization [GO:0060088]; cerebellar Purkinje cell layer formation [GO:0021694]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; establishment of protein localization [GO:0045184]; inner ear receptor cell stereocilium organization [GO:0060122]; paranodal junction maintenance [GO:1990227]; positive regulation of gene expression [GO:0010628]; retina homeostasis [GO:0001895]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]	cellular response to nerve growth factor stimulus [GO:1990090]; endosomal transport [GO:0016197]; endosome to plasma membrane protein transport [GO:0099638]; establishment of protein localization to plasma membrane [GO:0061951]; intracellular protein transport [GO:0006886]; negative regulation of inward rectifier potassium channel activity [GO:1903609]; nervous system development [GO:0007399]; positive regulation of AMPA glutamate receptor clustering [GO:1904719]; response to methamphetamine hydrochloride [GO:1904313]; retrograde transport, endosome to plasma membrane [GO:1990126]; signal transduction [GO:0007165]	auditory receptor cell stereocilium organization [GO:0060088]; cerebellar Purkinje cell layer formation [GO:0021694]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; establishment of protein localization [GO:0045184]; inner ear receptor cell stereocilium organization [GO:0060122]; paranodal junction maintenance [GO:1990227]; positive regulation of gene expression [GO:0010628]; retina homeostasis [GO:0001895]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; immunological synapse [GO:0001772]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	actin filament [GO:0005884]; cell junction [GO:0030054]; ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; growth cone [GO:0030426]; periciliary membrane compartment [GO:1990075]; photoreceptor connecting cilium [GO:0032391]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; stereocilia ankle link [GO:0002141]; stereocilia ankle link complex [GO:0002142]; stereocilium [GO:0032420]; stereocilium tip [GO:0032426]; synapse [GO:0045202]; USH2 complex [GO:1990696]	ionotropic glutamate receptor binding [GO:0035255]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol binding [GO:0035091]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d3qe2a3_d1fb3b4__1	Metazoa		Chordata		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	
d3qe2b1_d2qmyb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]
d3qe2b2_d5vw8a1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	chloroplast [GO:0009507]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d3qe8a__d2rb0x___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3qe8b__d2g4nc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; lactose biosynthetic process [GO:0005989]; response to 11-deoxycorticosterone [GO:1903496]; response to dehydroepiandrosterone [GO:1903494]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; lactose synthase activity [GO:0004461]
d3qe8b__d2rb2x___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3qegl1_d5b3jf2__1		Metazoa		Chordata		cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; NMDA selective glutamate receptor complex [GO:0017146]; postsynaptic membrane [GO:0045211]; metal ion binding [GO:0046872]; NMDA glutamate receptor activity [GO:0004972]; protein heterotetramerization [GO:0051290]; response to zinc ion [GO:0010043]		protein heterotetramerization [GO:0051290]; response to zinc ion [GO:0010043]		cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; NMDA selective glutamate receptor complex [GO:0017146]; postsynaptic membrane [GO:0045211]		metal ion binding [GO:0046872]; NMDA glutamate receptor activity [GO:0004972]
d3qehb1_d3auvb1__1												
d3qehd1_d2yxma1__1		Metazoa		Chordata		cytosol [GO:0005829]; myofibril [GO:0030016]; myosin filament [GO:0032982]; actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]		cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]		cytosol [GO:0005829]; myofibril [GO:0030016]; myosin filament [GO:0032982]		actin binding [GO:0003779]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]
d3qehd1_d4lcub1__1				Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d3qehd2_d4kjwd2__1				Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3qehf1_d3ared2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qehh1_d1ad0c2__1												
d3qehh1_d4lsql1__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d3qeqa2_d2mhac1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3qeqa2_d5jdja1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d3qeqb1_d4okvd1__1	Metazoa	Metazoa	Chordata	Arthropoda	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qeqd2_d4ktdl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qeqe1_d1f11b2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qeqe2_d2fx8m1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d3qesa1_d1xhzb1__1					3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]
d3qeua1_d1a6zd___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3qeud1_d5n2dc1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]		
d3qeue1_d2wzpk1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	virus tail, baseplate [GO:0098025]		
d3qeue1_d3lh2k1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]			
d3qeue2_d4zakd1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3qeza__d1so3b___1			Euryarchaeota	Proteobacteria	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; L-ascorbic acid catabolic process [GO:0019854]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	3-dehydro-L-gulonate-6-phosphate decarboxylase activity [GO:0033982]; magnesium ion binding [GO:0000287]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3qezb__d2flih___1			Euryarchaeota	Firmicutes	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]
d3qf2b__d1pn5a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; NLRP3 inflammasome complex [GO:0072559]; nucleus [GO:0005634]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; peptidoglycan binding [GO:0042834]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptidoglycan [GO:0071224]; cytokine secretion involved in immune response [GO:0002374]; defense response [GO:0006952]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta production [GO:0032611]; interleukin-1 secretion [GO:0050701]; interleukin-18 production [GO:0032621]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta secretion [GO:0050713]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein deubiquitination [GO:0016579]; signal transduction [GO:0007165]	cytosol [GO:0005829]; inflammasome complex [GO:0061702]; NLRP1 inflammasome complex [GO:0072558]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; neuron apoptotic process [GO:0051402]; NLRP1 inflammasome complex assembly [GO:1904784]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of interleukin-1 beta secretion [GO:0050718]; regulation of inflammatory response [GO:0050727]; response to muramyl dipeptide [GO:0032495]; viral process [GO:0016032]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptidoglycan [GO:0071224]; cytokine secretion involved in immune response [GO:0002374]; defense response [GO:0006952]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-18 production [GO:0032621]; interleukin-1 beta production [GO:0032611]; interleukin-1 secretion [GO:0050701]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta secretion [GO:0050713]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein deubiquitination [GO:0016579]; signal transduction [GO:0007165]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; neuron apoptotic process [GO:0051402]; NLRP1 inflammasome complex assembly [GO:1904784]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of interleukin-1 beta secretion [GO:0050718]; regulation of inflammatory response [GO:0050727]; response to muramyl dipeptide [GO:0032495]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi membrane [GO:0000139]; NLRP3 inflammasome complex [GO:0072559]; nucleus [GO:0005634]	cytosol [GO:0005829]; inflammasome complex [GO:0061702]; NLRP1 inflammasome complex [GO:0072558]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; peptidoglycan binding [GO:0042834]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]
d3qf4b2_d2jlzb1__1			Thermotogae		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3qfac1_d3csha2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3qfad1_d1eohd2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3qfbc1_d4gtub2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; long-chain fatty acid biosynthetic process [GO:0042759]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; long-chain fatty acid biosynthetic process [GO:0042759]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d3qfcb1_d4la4a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NAD binding [GO:0051287]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NADP binding [GO:0050661]; p-benzoquinone reductase (NADPH) activity [GO:0018541]; 4-nitrophenol catabolic process [GO:0046196]; aromatic compound catabolic process [GO:0019439]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	4-nitrophenol catabolic process [GO:0046196]; aromatic compound catabolic process [GO:0019439]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; p-benzoquinone reductase (NADPH) activity [GO:0018541]
d3qfcb3_d5vw2a2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	chloroplast [GO:0009507]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d3qfdb1_d3vxta2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qfdb1_d4jj5a1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qfje1_d5mp6q2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qfje2_d2cmrl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qfma__d5osig___1		Metazoa	Firmicutes	Chordata	nucleotide binding [GO:0000166]	cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; retromer complex [GO:0030904]; retromer, cargo-selective complex [GO:0030906]; metal ion binding [GO:0046872]; endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]		endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]		cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; retromer, cargo-selective complex [GO:0030906]; retromer complex [GO:0030904]	nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]
d3qfna__d3v4yc1__1		Metazoa	Firmicutes	Chordata	nucleotide binding [GO:0000166]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	nucleotide binding [GO:0000166]	cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]
d3qfnb__d4zvzd___1		Metazoa	Firmicutes	Chordata	nucleotide binding [GO:0000166]	chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; DNA repair [GO:0006281]; histone dephosphorylation [GO:0016576]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; response to arachidonic acid [GO:1904550]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]; transcription, DNA-templated [GO:0006351]		chaperone complex [GO:0101031]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; proximal dendrite [GO:1990635]	nucleotide binding [GO:0000166]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; G-protein alpha-subunit binding [GO:0001965]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]
d3qfob__d1it6b___1		Metazoa	Firmicutes	Chordata	nucleotide binding [GO:0000166]	cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; protein-containing complex [GO:0032991]; PTW/PP1 phosphatase complex [GO:0072357]; lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]		cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; neuron differentiation [GO:0030182]; positive regulation of glial cell proliferation [GO:0060252]; protein dephosphorylation [GO:0006470]; regulation of circadian rhythm [GO:0042752]; regulation of nucleocytoplasmic transport [GO:0046822]		cleavage furrow [GO:0032154]; condensed chromosome kinetochore [GO:0000777]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	nucleotide binding [GO:0000166]	lamin binding [GO:0005521]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; RNA binding [GO:0003723]
d3qfra1_d1h66a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3qfra3_d1tlla3__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]; ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; brain development [GO:0007420]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; establishment of protein localization [GO:0045184]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of hepatic stellate cell contraction [GO:0061875]; negative regulation of insulin secretion [GO:0046676]; negative regulation of iron ion transmembrane transport [GO:0034760]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]; retrograde trans-synaptic signaling by nitric oxide [GO:0098924]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	azurophil granule [GO:0042582]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; postsynaptic specialization, intracellular component [GO:0099091]; protein-containing complex [GO:0032991]; sarcolemma [GO:0042383]; secretory granule [GO:0030141]; synapse [GO:0045202]; vesicle membrane [GO:0012506]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	ATPase binding [GO:0051117]; cadmium ion binding [GO:0046870]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; ion channel binding [GO:0044325]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; oxidoreductase activity [GO:0016491]; phosphoprotein binding [GO:0051219]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; sodium channel regulator activity [GO:0017080]; zinc ion binding [GO:0008270]
d3qfrb1_d3f6sf___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3qfua2_d5aqqc2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; luminal surveillance complex [GO:0034099]; membrane [GO:0016020]; nucleus [GO:0005634]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; fungal-type cell wall beta-glucan biosynthetic process [GO:0070880]; karyogamy involved in conjugation with cellular fusion [GO:0000742]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]; ubiquitin-dependent ERAD pathway [GO:0030433]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; fungal-type cell wall beta-glucan biosynthetic process [GO:0070880]; karyogamy involved in conjugation with cellular fusion [GO:0000742]; posttranslational protein targeting to membrane, translocation [GO:0031204]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]; ubiquitin-dependent ERAD pathway [GO:0030433]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum chaperone complex [GO:0034663]; endoplasmic reticulum lumen [GO:0005788]; luminal surveillance complex [GO:0034099]; membrane [GO:0016020]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3qg7l2_d5lmwa1__1												
d3qgva1_d1e4la___1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]		carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]		chloroplast [GO:0009507]		beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]
d3qgza__d1y23a___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]	catalytic activity [GO:0003824]; nucleotide metabolic process [GO:0009117]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]	nucleotide metabolic process [GO:0009117]	cytoplasm [GO:0005737]; histone deacetylase complex [GO:0000118]		hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]	catalytic activity [GO:0003824]
d3qh3b1_d2wzpl1__1						virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		cell adhesion [GO:0007155]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		virus tail, baseplate [GO:0098025]		
d3qh3b2_d5lcvl1__1						extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3qh3c1_d4webl1__1						host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3qh3c2_d4kjqf2__1				Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3qh3d2_d4y4hg1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d3qhda__d3elcb1__1			Proteobacteria	Proteobacteria	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]; ubiquinone biosynthetic process [GO:0006744]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; identical protein binding [GO:0042802]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d3qhfl1_d3bzda___1				Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d3qhfl2_d4kk9f1__1				Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3qhsj__d5szda1__1			Proteobacteria	Aquificae	cytosol [GO:0005829]; bent DNA binding [GO:0003681]; RNA binding [GO:0003723]; negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]; RNA binding [GO:0003723]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]	cytosol [GO:0005829]	bent DNA binding [GO:0003681]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3qhta__d5m93b1__1	Fungi	Metazoa	Ascomycota	Chordata	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]; identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	protein sumoylation [GO:0016925]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3qhtb__d5chwd2__1	Fungi	Metazoa	Ascomycota	Chordata	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]; identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]; protein sumoylation [GO:0016925]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	protein sumoylation [GO:0016925]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3qhtd__d1cd9d1__1	Fungi	Metazoa	Ascomycota	Chordata	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]; identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]; protein sumoylation [GO:0016925]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]; cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	protein sumoylation [GO:0016925]	cellular response to cytokine stimulus [GO:0071345]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte differentiation [GO:0030851]; immune response [GO:0006955]; multicellular organism development [GO:0007275]; negative regulation of neuron death [GO:1901215]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of myeloid cell differentiation [GO:0045639]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to ethanol [GO:0045471]	condensed nuclear chromosome [GO:0000794]; nucleus [GO:0005634]; septin ring [GO:0005940]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein tag [GO:0031386]; ubiquitin-like protein ligase binding [GO:0044389]	cytokine activity [GO:0005125]; enzyme binding [GO:0019899]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; growth factor activity [GO:0008083]
d3qhzl1_d1i7td1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3qhzl2_d5hd8f1__1				Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3qi0f__d1a12a___1		Metazoa	Actinobacteria	Chordata	metal ion binding [GO:0046872]	chromatin [GO:0000785]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; chromatin binding [GO:0003682]; histone binding [GO:0042393]; nucleosomal DNA binding [GO:0031492]; nucleosome binding [GO:0031491]; protein heterodimerization activity [GO:0046982]; Ran GTPase binding [GO:0008536]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]; sulfate binding [GO:0043199]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic spindle organization [GO:0007052]; protein heterotetramerization [GO:0051290]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]; viral process [GO:0016032]		cell division [GO:0051301]; chromosome segregation [GO:0007059]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic spindle organization [GO:0007052]; protein heterotetramerization [GO:0051290]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]; viral process [GO:0016032]		chromatin [GO:0000785]; condensed nuclear chromosome [GO:0000794]; cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]	chromatin binding [GO:0003682]; histone binding [GO:0042393]; nucleosomal DNA binding [GO:0031492]; nucleosome binding [GO:0031491]; protein heterodimerization activity [GO:0046982]; Ran GTPase binding [GO:0008536]; Ran guanyl-nucleotide exchange factor activity [GO:0005087]; sulfate binding [GO:0043199]
d3qi3a__d5tzhd___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d3qi9a1_d2bsua3__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qi9a2_d3hfml1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3qi9c1_d3nfpb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]; interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]; activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation-induced cell death of T cells [GO:0006924]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-2-mediated signaling pathway [GO:0038110]; MAPK cascade [GO:0000165]; negative regulation of defense response to virus [GO:0050687]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response [GO:0050728]; negative regulation of T cell proliferation [GO:0042130]; Notch signaling pathway [GO:0007219]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of T cell differentiation [GO:0045582]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of T cell homeostatic proliferation [GO:0046013]; regulation of T cell tolerance induction [GO:0002664]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; interleukin-2 receptor complex [GO:0005893]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	interleukin-2 binding [GO:0019976]; interleukin-2 receptor activity [GO:0004911]
d3qi9c1_d3qfda2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3qi9d1_d5gksb2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qiba1_d1wbxa2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3qiba2_d3fjtb2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qibc1_d4h25b2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d3qibd1_d1kjva1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	aggresome [GO:0016235]; autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; proteasome complex [GO:0000502]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; cellular response to hypoxia [GO:0071456]; negative regulation of store-operated calcium channel activity [GO:1901340]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of protein ubiquitination [GO:0031398]; regulation of macroautophagy [GO:0016241]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; regulation of protein ubiquitination [GO:0031396]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; cellular response to hypoxia [GO:0071456]; negative regulation of store-operated calcium channel activity [GO:1901340]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of protein ubiquitination [GO:0031398]; regulation of macroautophagy [GO:0016241]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; regulation of protein ubiquitination [GO:0031396]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	aggresome [GO:0016235]; autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; proteasome complex [GO:0000502]		polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]
d3qiha__d2nxdb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3qihb__d6fiva___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d3qijb2_d1mk9f1__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]; 1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]; actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]; cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478]	activation of protein kinase activity [GO:0032147]; angiogenesis involved in wound healing [GO:0060055]; apolipoprotein A-I-mediated signaling pathway [GO:0038027]; apoptotic cell clearance [GO:0043277]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; mesodermal cell differentiation [GO:0048333]; negative chemotaxis [GO:0050919]; negative regulation of lipid storage [GO:0010888]; negative regulation of lipid transport [GO:0032369]; negative regulation of lipoprotein metabolic process [GO:0050748]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of bone resorption [GO:0045124]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of protein localization [GO:0032880]; regulation of serotonin uptake [GO:0051611]; smooth muscle cell migration [GO:0014909]; substrate adhesion-dependent cell spreading [GO:0034446]; tube development [GO:0035295]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral entry into host cell [GO:0046718]; wound healing [GO:0042060]	basolateral plasma membrane [GO:0016323]; cell cortex region [GO:0099738]; cell junction [GO:0030054]; cortical cytoskeleton [GO:0030863]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; intercellular bridge [GO:0045171]; mitotic spindle [GO:0072686]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; spectrin-associated cytoskeleton [GO:0014731]	alphav-beta3 integrin-HMGB1 complex [GO:0035868]; alphav-beta3 integrin-IGF-1-IGF1R complex [GO:0035867]; alphav-beta3 integrin-PKCalpha complex [GO:0035866]; alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integrin alphav-beta3 complex [GO:0034683]; integrin complex [GO:0008305]; lamellipodium membrane [GO:0031258]; melanosome [GO:0042470]; microvillus membrane [GO:0031528]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; synapse [GO:0045202]	1-phosphatidylinositol binding [GO:0005545]; actin binding [GO:0003779]; calmodulin binding [GO:0005516]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein N-terminus binding [GO:0047485]; spectrin binding [GO:0030507]; structural constituent of cytoskeleton [GO:0005200]	cell adhesion molecule binding [GO:0050839]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; platelet-derived growth factor receptor binding [GO:0005161]; protease binding [GO:0002020]; protein disulfide isomerase activity [GO:0003756]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]
d3qima__d4elpb___1			Proteobacteria	Deinococcus-Thermus	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	metal ion binding [GO:0046872]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]	metal ion binding [GO:0046872]
d3qimb__d6bqeb___1			Proteobacteria		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]		negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]	
d3qiub1_d4p5me1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to interferon-gamma [GO:0071346]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell proliferation [GO:0042102]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; endosome membrane [GO:0010008]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]
d3qiud1_d2ny4d1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3qiud1_d2yd7b1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; protein tyrosine phosphatase activity [GO:0004725]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		cell adhesion molecule binding [GO:0050839]; protein tyrosine phosphatase activity [GO:0004725]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d3qj3a__d7pcka___1	Metazoa	Metazoa	Arthropoda	Chordata	cysteine-type peptidase activity [GO:0008234]	endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]; autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]		autophagy of mitochondrion [GO:0000422]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; intramembranous ossification [GO:0001957]; negative regulation of cartilage development [GO:0061037]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of keratinocyte differentiation [GO:0045616]; toll-like receptor signaling pathway [GO:0002224]		endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]	cysteine-type peptidase activity [GO:0008234]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; proteoglycan binding [GO:0043394]
d3qj3b__d5kycb___1	Metazoa	Metazoa	Arthropoda	Chordata	cysteine-type peptidase activity [GO:0008234]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cysteine-type peptidase activity [GO:0008234]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3qj7a__d2tsra___1		Metazoa	Actinobacteria	Chordata	cytosol [GO:0005829]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP catabolic process [GO:0046079]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; cofactor binding [GO:0048037]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; mRNA binding [GO:0003729]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; pyrimidine nucleobase metabolic process [GO:0006206]; regulation of translation [GO:0006417]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organic cyclic compound [GO:0014070]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]; uracil metabolic process [GO:0019860]	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP catabolic process [GO:0046079]; response to antibiotic [GO:0046677]	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; pyrimidine nucleobase metabolic process [GO:0006206]; regulation of translation [GO:0006417]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organic cyclic compound [GO:0014070]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]; uracil metabolic process [GO:0019860]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]	thymidylate synthase activity [GO:0004799]	cofactor binding [GO:0048037]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; mRNA binding [GO:0003729]; nucleotide binding [GO:0000166]; protein homodimerization activity [GO:0042803]; sequence-specific mRNA binding [GO:1990825]; thymidylate synthase activity [GO:0004799]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3qj8b__d1obja___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]	amidase activity [GO:0004040]	fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]		acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]	amidase activity [GO:0004040]
d3qjca__d3lqda___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3qjcb__d2d5zb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3qjdb__d2w6xa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3qjea__d1j41b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3qjed__d1cmyb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3qjfb2_d2jb5h1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qjfd2_d1jnha2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	plasma membrane [GO:0005886]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	plasma membrane [GO:0005886]		
d3qjgb__d1e20a___1		Viridiplantae	Firmicutes	Streptophyta	catalytic activity [GO:0003824]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; phosphopantothenoylcysteine decarboxylase activity [GO:0004633]; coenzyme A biosynthetic process [GO:0015937]; hyperosmotic salinity response [GO:0042538]; regulation of growth [GO:0040008]		coenzyme A biosynthetic process [GO:0015937]; hyperosmotic salinity response [GO:0042538]; regulation of growth [GO:0040008]		cytosol [GO:0005829]	catalytic activity [GO:0003824]; nucleotide binding [GO:0000166]	phosphopantothenoylcysteine decarboxylase activity [GO:0004633]
d3qjgb__d4zala___1			Firmicutes	Proteobacteria	catalytic activity [GO:0003824]; nucleotide binding [GO:0000166]	carboxy-lyase activity [GO:0016831]; flavin prenyltransferase activity [GO:0106141]; prenyltransferase activity [GO:0004659]; coenzyme biosynthetic process [GO:0009108]		coenzyme biosynthetic process [GO:0009108]			catalytic activity [GO:0003824]; nucleotide binding [GO:0000166]	carboxy-lyase activity [GO:0016831]; flavin prenyltransferase activity [GO:0106141]; prenyltransferase activity [GO:0004659]
d3qjhb1_d5tgbl1__1												
d3qjhb2_d1fnsh1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qjhd2_d3aazl1__1												
d3qjqb2_d2aana___1			Deinococcus-Thermus	Chloroflexi	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3qjsb2_d2j56a___1			Deinococcus-Thermus	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3qk8f__d1hzdb___1		Metazoa	Actinobacteria	Chordata	catalytic activity [GO:0003824]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]; branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]		branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]	enoyl-CoA hydratase activity [GO:0004300]; itaconyl-CoA hydratase activity [GO:0050011]; methylglutaconyl-CoA hydratase activity [GO:0004490]; mRNA 3'-UTR binding [GO:0003730]
d3qkac1_d1nzyb___1			Actinobacteria	Proteobacteria	catalytic activity [GO:0003824]	4-chlorobenzoyl-CoA dehalogenase activity [GO:0018787]; coenzyme A metabolic process [GO:0015936]		coenzyme A metabolic process [GO:0015936]			catalytic activity [GO:0003824]	4-chlorobenzoyl-CoA dehalogenase activity [GO:0018787]
d3qked1_d1ecqc2__1			Proteobacteria	Proteobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	D-glucarate catabolic process [GO:0042838]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3qkeh1_d4izga1__1			Proteobacteria	Proteobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	metal ion binding [GO:0046872]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; amino-acid betaine catabolic process [GO:0006579]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	amino-acid betaine catabolic process [GO:0006579]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	metal ion binding [GO:0046872]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d3qkfe1_d1wueb2__1				Firmicutes		hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]		menaquinone biosynthetic process [GO:0009234]				hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3qkga__d4os8b___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; calcium channel inhibitor activity [GO:0019855]; calcium oxalate binding [GO:0046904]; heme binding [GO:0020037]; IgA binding [GO:0019862]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase inhibitor activity [GO:0004867]; cell adhesion [GO:0007155]; female pregnancy [GO:0007565]; heme catabolic process [GO:0042167]; negative regulation of immune response [GO:0050777]; negative regulation of JNK cascade [GO:0046329]; protein catabolic process [GO:0030163]; protein-chromophore linkage [GO:0018298]; receptor-mediated endocytosis [GO:0006898]; viral process [GO:0016032]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	cell adhesion [GO:0007155]; female pregnancy [GO:0007565]; heme catabolic process [GO:0042167]; negative regulation of immune response [GO:0050777]; negative regulation of JNK cascade [GO:0046329]; protein catabolic process [GO:0030163]; protein-chromophore linkage [GO:0018298]; receptor-mediated endocytosis [GO:0006898]; viral process [GO:0016032]	cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	calcium channel inhibitor activity [GO:0019855]; calcium oxalate binding [GO:0046904]; heme binding [GO:0020037]; IgA binding [GO:0019862]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase inhibitor activity [GO:0004867]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d3qkvb__d1obia___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]; acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]	amidase activity [GO:0004040]	fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631]; monoacylglycerol catabolic process [GO:0052651]; negative regulation of blood vessel diameter [GO:0097756]		endoplasmic reticulum membrane [GO:0005789]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; organelle membrane [GO:0031090]		acylglycerol lipase activity [GO:0047372]; amidase activity [GO:0004040]; anandamide amidohydrolase activity [GO:0103073]; fatty acid amide hydrolase activity [GO:0017064]; hydrolase activity, acting on ester bonds [GO:0016788]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; oleamide hydrolase activity [GO:0102077]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]	amidase activity [GO:0004040]
d3qkzb__d5keta___1	Metazoa	Metazoa	Chordata	Arthropoda	cytosol [GO:0005829]; mitochondrion [GO:0005739]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]			cytosol [GO:0005829]; mitochondrion [GO:0005739]		alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3ql1a__d3rska___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d3ql2a__d1h53a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]
d3qlrb1_d3s9ub1__1	Fungi		Ascomycota	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d3qlsb1_d1seje1__1	Fungi		Ascomycota	Apicomplexa	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]
d3qlwb__d4kl9a1__1	Fungi		Ascomycota	Actinobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]
d3qlxa1_d1rx2a___1	Fungi		Ascomycota	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d3qlya1_d2w9sb___1	Fungi		Ascomycota	Firmicutes	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3qlyb1_d1dhfa___1	Fungi	Metazoa	Ascomycota	Chordata	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3qlzb1_d3fq0a___1	Fungi		Ascomycota		dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]		dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]	
d3qm6a__d1b33c___1	Metazoa		Chordata	Cyanobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; photosynthesis [GO:0015979]		photosynthesis [GO:0015979]		phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3qm8a__d3ugya___1	Metazoa	Metazoa	Chordata	Mollusca	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3qmaa__d5b13e___1	Metazoa		Chordata	Rhodophyta	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3qmla2_d3bexf2__1	Fungi		Ascomycota	Thermotogae	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; adenyl-nucleotide exchange factor activity [GO:0000774]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	cytoplasm [GO:0005737]	adenyl-nucleotide exchange factor activity [GO:0000774]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d3qmlb1_d2q1nb2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; adenyl-nucleotide exchange factor activity [GO:0000774]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	adenyl-nucleotide exchange factor activity [GO:0000774]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3qmlb2_d2d1ka2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; adenyl-nucleotide exchange factor activity [GO:0000774]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]	extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]; apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]	SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]	apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]	adenyl-nucleotide exchange factor activity [GO:0000774]	actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]
d3qmma__d1ku0a___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]		lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d3qmqc1_d3lgnb1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity [GO:0002952]; intramolecular oxidoreductase activity, interconverting aldoses and ketoses [GO:0016861]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; heme catabolic process [GO:0042167]; iron import into cell [GO:0033212]		heme catabolic process [GO:0042167]; iron import into cell [GO:0033212]	cytosol [GO:0005829]	cell [GO:0005623]; cytoplasm [GO:0005737]	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity [GO:0002952]; intramolecular oxidoreductase activity, interconverting aldoses and ketoses [GO:0016861]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]
d3qmqc1_d4fpic___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity [GO:0002952]; intramolecular oxidoreductase activity, interconverting aldoses and ketoses [GO:0016861]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]		beta-ketoadipate pathway [GO:0042952]	cytosol [GO:0005829]		(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity [GO:0002952]; intramolecular oxidoreductase activity, interconverting aldoses and ketoses [GO:0016861]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]	muconolactone delta-isomerase activity [GO:0016159]
d3qmsa__d1dqxc___1		Fungi	Euryarchaeota	Ascomycota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; UMP biosynthetic process [GO:0006222]		cytosol [GO:0005829]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3qmsa__d1thfd___1			Euryarchaeota	Thermotogae	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; histidine biosynthetic process [GO:0000105]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	histidine biosynthetic process [GO:0000105]		cytoplasm [GO:0005737]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]
d3qmta__d3o06c___1		Fungi	Euryarchaeota	Ascomycota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]		glutaminase complex [GO:1903600]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3qn0b__d1vaxf1__1			Proteobacteria		6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]		queuosine biosynthetic process [GO:0008616]				6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	
d3qn0e__d4ntkf___1			Proteobacteria	Proteobacteria	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	queuosine biosynthetic process [GO:0008616]	queuosine biosynthetic process [GO:0008616]			6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d3qn2a__d1rz9e___1					host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; DNA replication [GO:0006260]; viral genome replication [GO:0019079]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]; viral genome replication [GO:0019079]	host cell nucleus [GO:0042025]		ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d3qn2a__d4lmda___1					host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	host cell nucleus [GO:0042025]; ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; DNA replication [GO:0006260]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA unwinding involved in DNA replication [GO:0006268]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; suppression by virus of host JAK1 activity [GO:0039576]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	host cell nucleus [GO:0042025]	host cell nucleus [GO:0042025]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; double-stranded DNA binding [GO:0003690]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; DNA replication origin binding [GO:0003688]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3qn3a1_d2gl5b2__1			Proteobacteria	Proteobacteria	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	metal ion binding [GO:0046872]	glycolytic process [GO:0006096]		cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	metal ion binding [GO:0046872]
d3qn3a2_d3pwib2__1			Proteobacteria	Proteobacteria	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	glycolytic process [GO:0006096]	D-glucarate catabolic process [GO:0042838]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3qn3b1_d4ihcb1__1			Proteobacteria	Proteobacteria	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	glycolytic process [GO:0006096]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d3qn3b1_d4j1ob1__1			Proteobacteria	Proteobacteria	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	metal ion binding [GO:0046872]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; amino-acid betaine catabolic process [GO:0006579]	glycolytic process [GO:0006096]	amino-acid betaine catabolic process [GO:0006579]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	metal ion binding [GO:0046872]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d3qn3b2_d1sjdc1__1			Proteobacteria	Actinobacteria	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	glycolytic process [GO:0006096]	menaquinone biosynthetic process [GO:0009234]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3qn8a__d2hb3b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3qn9b__d1nbug___1			Proteobacteria	Actinobacteria	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	queuosine biosynthetic process [GO:0008616]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]			6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	dihydroneopterin aldolase activity [GO:0004150]; isomerase activity [GO:0016853]; oxidoreductase activity [GO:0016491]
d3qnad__d1is7f___1		Metazoa	Proteobacteria	Chordata	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	queuosine biosynthetic process [GO:0008616]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]
d3qnde__d2oj5a1__1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral outer capsid [GO:0039624]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	viral outer capsid [GO:0039624]	metal ion binding [GO:0046872]	
d3qndf__d3u6xo2__1					viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]	virus tail, baseplate [GO:0098025]	metal ion binding [GO:0046872]	
d3qndg__d2w9ld___1		Metazoa		Chordata	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell junction [GO:0030054]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; actin cytoskeleton reorganization [GO:0031532]; AV node cell to bundle of His cell communication [GO:0086067]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	actin cytoskeleton reorganization [GO:0031532]; AV node cell-bundle of His cell adhesion involved in cell communication [GO:0086072]; AV node cell to bundle of His cell communication [GO:0086067]; cardiac muscle fiber development [GO:0048739]; cell-cell junction organization [GO:0045216]; defense response to virus [GO:0051607]; epithelial structure maintenance [GO:0010669]; gamma-delta T cell activation [GO:0046629]; germ cell migration [GO:0008354]; heart development [GO:0007507]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homotypic cell-cell adhesion [GO:0034109]; leukocyte migration [GO:0050900]; mitochondrion organization [GO:0007005]; neutrophil chemotaxis [GO:0030593]; regulation of AV node cell action potential [GO:0098904]; regulation of immune response [GO:0050776]; transepithelial transport [GO:0070633]	viral capsid [GO:0019028]	acrosomal vesicle [GO:0001669]; adherens junction [GO:0005912]; apicolateral plasma membrane [GO:0016327]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; filopodium [GO:0030175]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; membrane raft [GO:0045121]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	metal ion binding [GO:0046872]	beta-catenin binding [GO:0008013]; cell adhesion molecule binding [GO:0050839]; cell adhesive protein binding involved in AV node cell-bundle of His cell communication [GO:0086082]; connexin binding [GO:0071253]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3qnga__d1flya___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3qnsa__d1tr0n___1		Viridiplantae	Actinobacteria	Streptophyta	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	
d3qnva__d1jqga1__1		Metazoa	Firmicutes	Arthropoda	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]					metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d3qnva__d3prta___1			Firmicutes	Firmicutes	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]					metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d3qnxa1_d4fq1l1__1												
d3qnxb2_d5cckl2__1												
d3qnya2_d3s96d1__1												
d3qnyb2_d5o4ed1__1		Metazoa		Chordata		extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]		adaptive immune response [GO:0002250]		extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		
d3qnyc1_d1k4ca2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qnyc2_d3sknc2__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d3qnyc2_d5mo9x___1		Metazoa		Chordata		axon [GO:0030424]; axon terminus [GO:0043679]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; brain-derived neurotrophic factor binding [GO:0048403]; brain-derived neurotrophic factor-activated receptor activity [GO:0060175]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; activation of phospholipase C activity [GO:0007202]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cellular response to amino acid stimulus [GO:0071230]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; circadian rhythm [GO:0007623]; feeding behavior [GO:0007631]; glutamate secretion [GO:0014047]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuronal action potential propagation [GO:0019227]; neurotrophin TRK receptor signaling pathway [GO:0048011]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system neuron development [GO:0048935]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; retinal rod cell development [GO:0046548]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trans-synaptic signaling by neuropeptide, modulating synaptic transmission [GO:0099551]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]		activation of phospholipase C activity [GO:0007202]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cellular response to amino acid stimulus [GO:0071230]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; circadian rhythm [GO:0007623]; feeding behavior [GO:0007631]; glutamate secretion [GO:0014047]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; mechanoreceptor differentiation [GO:0042490]; myelination in peripheral nervous system [GO:0022011]; negative regulation of anoikis [GO:2000811]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; neuronal action potential propagation [GO:0019227]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neurotrophin TRK receptor signaling pathway [GO:0048011]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system neuron development [GO:0048935]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; regulation of MAPK cascade [GO:0043408]; regulation of protein kinase B signaling [GO:0051896]; retinal rod cell development [GO:0046548]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; trans-synaptic signaling by neuropeptide, modulating synaptic transmission [GO:0099551]; vasculogenesis [GO:0001570]		axon [GO:0030424]; axon terminus [GO:0043679]; cell junction [GO:0030054]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]		ATP binding [GO:0005524]; brain-derived neurotrophic factor-activated receptor activity [GO:0060175]; brain-derived neurotrophic factor binding [GO:0048403]; neurotrophin binding [GO:0043121]; neurotrophin receptor activity [GO:0005030]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3qo3f__d4mmka___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; bent DNA binding [GO:0003681]; RNA binding [GO:0003723]; negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]	cytosol [GO:0005829]	bent DNA binding [GO:0003681]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3qoja__d4pnya___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3qopa1_d3ogjb___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]
d3qopa1_d4n9ia1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3qorc1_d2h53s1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; cadherin binding [GO:0045296]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; developmental process [GO:0032502]; protein folding [GO:0006457]	cytoplasm [GO:0005737]; protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cell cycle [GO:0007049]; cell division [GO:0051301]; developmental process [GO:0032502]; protein folding [GO:0006457]	protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein homooligomerization [GO:0051260]; response to heat [GO:0009408]; response to reactive oxygen species [GO:0000302]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	cadherin binding [GO:0045296]; unfolded protein binding [GO:0051082]	protein self-association [GO:0043621]; unfolded protein binding [GO:0051082]
d3qorc1_d2xcmc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; cadherin binding [GO:0045296]; unfolded protein binding [GO:0051082]; cell cycle [GO:0007049]; cell division [GO:0051301]; developmental process [GO:0032502]; protein folding [GO:0006457]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; cellular response to auxin stimulus [GO:0071365]; defense response [GO:0006952]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; protein stabilization [GO:0050821]; regulation of defense response to fungus, incompatible interaction [GO:2000072]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell cycle [GO:0007049]; cell division [GO:0051301]; developmental process [GO:0032502]; protein folding [GO:0006457]	cellular response to auxin stimulus [GO:0071365]; defense response [GO:0006952]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; protein stabilization [GO:0050821]; regulation of defense response to fungus, incompatible interaction [GO:2000072]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	cadherin binding [GO:0045296]; unfolded protein binding [GO:0051082]	
d3qp3b1_d1evtc1__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3qpbj__d4rj2d___1			Firmicutes		cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]		nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]		cytoplasm [GO:0005737]		uridine phosphorylase activity [GO:0004850]	
d3qpbo__d4i2vf___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	uridine phosphorylase activity [GO:0004850]	uridine phosphorylase activity [GO:0004850]
d3qpbp__d4ogkd___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	uridine phosphorylase activity [GO:0004850]	uridine phosphorylase activity [GO:0004850]
d3qpfb__d2zble1__1			Firmicutes	Proteobacteria	catalytic activity [GO:0003824]	sulfoquinovose isomerase activity [GO:0061593]; 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde [GO:0061720]		6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde [GO:0061720]			catalytic activity [GO:0003824]	sulfoquinovose isomerase activity [GO:0061593]
d3qpga__d3aeob___1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	transsulfuration [GO:0019346]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	methionine gamma-lyase activity [GO:0018826]; pyridoxal phosphate binding [GO:0030170]
d3qpja__d4cpxb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3qpja__d5bwya___1				Apicomplexa	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3qpka1_d4n4yb2__1	Fungi		Ascomycota	Deinococcus-Thermus	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		extraorganismal space [GO:0043245]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d3qpka2_d1zdqc1__1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	extraorganismal space [GO:0043245]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3qpka3_d3plyc___1	Fungi		Ascomycota	Proteobacteria	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		extraorganismal space [GO:0043245]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3qpma__d5aixa1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	peroxiredoxin activity [GO:0051920]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d3qpmb__d1i5ga___1	Metazoa		Chordata		cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	peroxiredoxin activity [GO:0051920]	
d3qpmc__d2h1aa___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell [GO:0005623]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	peroxiredoxin activity [GO:0051920]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]
d3qpmc__d5ld0a1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	peroxiredoxin activity [GO:0051920]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3qpme__d2h1bb___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell [GO:0005623]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	peroxiredoxin activity [GO:0051920]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]
d3qpna__d4lkqa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3qppa__d4i15a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	axoneme [GO:0005930]; cytoplasm [GO:0005737]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; cell morphogenesis [GO:0000902]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	cell morphogenesis [GO:0000902]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]	axoneme [GO:0005930]; cytoplasm [GO:0005737]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]
d3qpqe1_d3ab0f___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qpqe2_d1f11d1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qpqi1_d5f3hb1__1		Metazoa		Chordata		cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]; cell development [GO:0048468]; cellular response to dexamethasone stimulus [GO:0071549]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of kinase activity [GO:0033673]; negative regulation of muscle hypertrophy [GO:0014741]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast proliferation [GO:2000818]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; negative regulation of skeletal muscle tissue growth [GO:0048632]; ovulation cycle process [GO:0022602]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; response to electrical stimulus [GO:0051602]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to gravity [GO:0009629]; response to heat [GO:0009408]; response to muscle activity [GO:0014850]; response to testosterone [GO:0033574]; skeletal muscle atrophy [GO:0014732]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]		cell development [GO:0048468]; cellular response to dexamethasone stimulus [GO:0071549]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; myoblast migration involved in skeletal muscle regeneration [GO:0014839]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of kinase activity [GO:0033673]; negative regulation of muscle hypertrophy [GO:0014741]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myoblast proliferation [GO:2000818]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of satellite cell differentiation [GO:1902725]; negative regulation of skeletal muscle satellite cell proliferation [GO:1902723]; negative regulation of skeletal muscle tissue growth [GO:0048632]; ovulation cycle process [GO:0022602]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; response to electrical stimulus [GO:0051602]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to gravity [GO:0009629]; response to heat [GO:0009408]; response to muscle activity [GO:0014850]; response to testosterone [GO:0033574]; skeletal muscle atrophy [GO:0014732]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]		cell [GO:0005623]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; transforming growth factor beta receptor binding [GO:0005160]
d3qpqi1_d5l8jb1__1		Metazoa		Chordata		axon hillock [GO:0043203]; centriole [GO:0005814]; centrosome [GO:0005813]; chromosome passenger complex [GO:0032133]; cilium [GO:0005929]; condensed nuclear chromosome, centromeric region [GO:0000780]; cytosol [GO:0005829]; germinal vesicle [GO:0042585]; meiotic spindle [GO:0072687]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle pole [GO:0097431]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle midzone [GO:0051233]; spindle pole centrosome [GO:0031616]; ATP binding [GO:0005524]; histone serine kinase activity [GO:0035174]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; ubiquitin protein ligase binding [GO:0031625]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; anterior/posterior axis specification [GO:0009948]; cell division [GO:0051301]; centrosome localization [GO:0051642]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; G2/M transition of mitotic cell cycle [GO:0000086]; liver regeneration [GO:0097421]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neuron projection extension [GO:1990138]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autophosphorylation [GO:0046777]; protein localization to centrosome [GO:0071539]; protein phosphorylation [GO:0006468]; regulation of centrosome cycle [GO:0046605]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to wounding [GO:0009611]; spindle assembly involved in female meiosis I [GO:0007057]; spindle organization [GO:0007051]; ubiquitin-dependent protein catabolic process [GO:0006511]		anaphase-promoting complex-dependent catabolic process [GO:0031145]; anterior/posterior axis specification [GO:0009948]; cell division [GO:0051301]; centrosome localization [GO:0051642]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; G2/M transition of mitotic cell cycle [GO:0000086]; liver regeneration [GO:0097421]; mitotic cell cycle [GO:0000278]; mitotic centrosome separation [GO:0007100]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neuron projection extension [GO:1990138]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autophosphorylation [GO:0046777]; protein localization to centrosome [GO:0071539]; protein phosphorylation [GO:0006468]; regulation of centrosome cycle [GO:0046605]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to wounding [GO:0009611]; spindle assembly involved in female meiosis I [GO:0007057]; spindle organization [GO:0007051]; ubiquitin-dependent protein catabolic process [GO:0006511]		axon hillock [GO:0043203]; centriole [GO:0005814]; centrosome [GO:0005813]; chromosome passenger complex [GO:0032133]; cilium [GO:0005929]; condensed nuclear chromosome, centromeric region [GO:0000780]; cytosol [GO:0005829]; germinal vesicle [GO:0042585]; meiotic spindle [GO:0072687]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; mitotic spindle pole [GO:0097431]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; pronucleus [GO:0045120]; spindle [GO:0005819]; spindle microtubule [GO:0005876]; spindle midzone [GO:0051233]; spindle pole centrosome [GO:0031616]		ATP binding [GO:0005524]; histone serine kinase activity [GO:0035174]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; ubiquitin protein ligase binding [GO:0031625]
d3qpqi2_d4dkaa1__1						mitochondrion [GO:0005739]; alpha-catenin binding [GO:0045294]; nucleic acid binding [GO:0003676]; mitochondrial RNA modification [GO:1900864]; RNA nucleotide deletion [GO:0070706]; RNA nucleotide insertion [GO:0070705]		mitochondrial RNA modification [GO:1900864]; RNA nucleotide deletion [GO:0070706]; RNA nucleotide insertion [GO:0070705]		mitochondrion [GO:0005739]		alpha-catenin binding [GO:0045294]; nucleic acid binding [GO:0003676]
d3qpql2_d1dqtd___1		Metazoa		Chordata		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]		clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]		
d3qpxl1_d3he6b___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qq3e1_d3fzul1__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	
d3qq4b1_d1fl6l1__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]		amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]		cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]		protein homodimerization activity [GO:0042803]	
d3qq7a1_d1h5na1__1	Metazoa		Chordata	Proteobacteria	ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum unfolded protein response [GO:0030968]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; establishment of protein localization [GO:0045184]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; neutrophil degranulation [GO:0043312]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of apoptotic process [GO:0042981]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; ubiquitin-dependent ERAD pathway [GO:0030433]; viral genome replication [GO:0019079]		ATPase complex [GO:1904949]; azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; site of double-strand break [GO:0035861]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	periplasmic space [GO:0042597]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; molybdopterin cofactor binding [GO:0043546]; trimethylamine-N-oxide reductase (cytochrome c) activity [GO:0050626]
d3qq9c1_d4p4kh2__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d3qq9l2_d4nc1c___1												
d3qqba1_d4k3xc___1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d3qqea1_d3m5ha___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3qqea1_d4w8na1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3qqoc1_d2btvf2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	virion [GO:0019012]; structural molecule activity [GO:0005198]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	virion [GO:0019012]	host cell surface receptor binding [GO:0046789]	structural molecule activity [GO:0005198]
d3qqoc1_d2fk0e2__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3qr3a1_d1mw1a2__1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; amylosucrase activity [GO:0047669]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	amylosucrase activity [GO:0047669]
d3qr3b1_d4qdmb___1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	endo-1,4-beta-xylanase activity [GO:0031176]; metal ion binding [GO:0046872]
d3qr6a1_d2yp6d___1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cell [GO:0005623]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]
d3qr6a2_d2oa7b1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]
d3qr6a2_d5eckf2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d3qrba2_d4zmva1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3qrbb1_d3k5sb1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]; adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; endothelial cell migration [GO:0043542]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinocyte proliferation [GO:0043616]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Rac protein signal transduction [GO:0016601]; regulation of endocytosis [GO:0030100]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; Rho protein signal transduction [GO:0007266]; sprouting angiogenesis [GO:0002040]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	anchored component of membrane [GO:0031225]; catenin complex [GO:0016342]; caveola [GO:0005901]; cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; supramolecular fiber [GO:0099512]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	adiponectin binding [GO:0055100]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; low-density lipoprotein particle binding [GO:0030169]; protein homodimerization activity [GO:0042803]
d3qrbb2_d5jymc2__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	catenin complex [GO:0016342]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]; adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]	adherens junction organization [GO:0034332]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; hair cycle process [GO:0022405]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; keratinization [GO:0031424]; negative regulation of timing of catagen [GO:0051796]; negative regulation of transforming growth factor beta2 production [GO:0032912]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanosome transport [GO:1902910]; positive regulation of monophenol monooxygenase activity [GO:0032773]; regulation of hair cycle by canonical Wnt signaling pathway [GO:0060901]; response to drug [GO:0042493]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]	cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; protein homodimerization activity [GO:0042803]
d3qrma__d5p26a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3qrwa__d4itua___1			Actinobacteria	Proteobacteria	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	antibiotic biosynthetic process [GO:0017000]				oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3qrwb__d2aa3b1__1			Actinobacteria	Apicomplexa	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	antibiotic biosynthetic process [GO:0017000]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]			oxidoreductase activity [GO:0016491]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d3qrya__d3wc3a1__1		Metazoa	Firmicutes	Annelida	catalytic activity [GO:0003824]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]			catalytic activity [GO:0003824]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]
d3qsbb2_d2ntif1__1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	PCNA complex [GO:0043626]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	leading strand elongation [GO:0006272]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	PCNA complex [GO:0043626]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d3qsic__d3bkta___1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	protein-DNA complex [GO:0032993]; bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of DNA-templated transcription, initiation [GO:2000143]; protein homotetramerization [GO:0051289]; response to nickel cation [GO:0010045]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	negative regulation of DNA-templated transcription, initiation [GO:2000143]; protein homotetramerization [GO:0051289]; response to nickel cation [GO:0010045]	protein-DNA complex [GO:0032993]	protein-DNA complex [GO:0032993]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	bacterial-type RNA polymerase core promoter sequence-specific DNA binding [GO:0000985]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3qskb__d1hh6b2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qsma2_d1ryib2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]; cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	tetrahydrofolate metabolic process [GO:0046653]	cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	sarcosine oxidase activity [GO:0008115]	FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]
d3qsmb2_d1b37a2__1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	tetrahydrofolate metabolic process [GO:0046653]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	cytoplasm [GO:0005737]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	sarcosine oxidase activity [GO:0008115]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]
d3qssa2_d1ojdd2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	tetrahydrofolate metabolic process [GO:0046653]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	sarcosine oxidase activity [GO:0008115]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d3qssb2_d1o5wa2__1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	integral component of membrane [GO:0016021]; mitochondrial outer membrane [GO:0005741]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; serotonin binding [GO:0051378]; catecholamine catabolic process [GO:0042424]; neurotransmitter catabolic process [GO:0042135]; phenylethylamine metabolic process [GO:0042443]; serotonin metabolic process [GO:0042428]	tetrahydrofolate metabolic process [GO:0046653]	catecholamine catabolic process [GO:0042424]; neurotransmitter catabolic process [GO:0042135]; phenylethylamine metabolic process [GO:0042443]; serotonin metabolic process [GO:0042428]	cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]; mitochondrial outer membrane [GO:0005741]	sarcosine oxidase activity [GO:0008115]	flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; serotonin binding [GO:0051378]
d3qsvd__d3kmpa___1	Metazoa	Metazoa	Chordata	Chordata	activin responsive factor complex [GO:0032444]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; collagen binding [GO:0005518]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; filamin binding [GO:0031005]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molecular function regulator [GO:0098772]; protein homodimerization activity [GO:0042803]; proximal promoter sequence-specific DNA binding [GO:0000987]; R-SMAD binding [GO:0070412]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; SMAD binding [GO:0046332]; sulfate binding [GO:0043199]; transcription coregulator activity [GO:0003712]; transcription regulatory region DNA binding [GO:0044212]; transforming growth factor beta receptor, common-partner cytoplasmic mediator activity [GO:0030616]; anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; brainstem development [GO:0003360]; branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac septum development [GO:0003279]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular iron ion homeostasis [GO:0006879]; cellular response to glucose stimulus [GO:0071333]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; endocardial cell differentiation [GO:0060956]; endoderm development [GO:0007492]; endothelial cell activation [GO:0042118]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; ERK1 and ERK2 cascade [GO:0070371]; female gonad development [GO:0008585]; female gonad morphogenesis [GO:0061040]; formation of anatomical boundary [GO:0048859]; gastrulation [GO:0007369]; gastrulation with mouth forming second [GO:0001702]; in utero embryonic development [GO:0001701]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; male gonad development [GO:0008584]; mesendoderm development [GO:0048382]; mesoderm development [GO:0007498]; metanephric mesenchyme morphogenesis [GO:0072133]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cardiac myofibril assembly [GO:1905305]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural crest cell differentiation [GO:0014033]; neuron fate commitment [GO:0048663]; osteoblast differentiation [GO:0001649]; outflow tract septum morphogenesis [GO:0003148]; ovarian follicle development [GO:0001541]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell proliferation involved in heart valve morphogenesis [GO:0003251]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of luteinizing hormone secretion [GO:0033686]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; protein homotrimerization [GO:0070207]; regulation of binding [GO:0051098]; regulation of cell population proliferation [GO:0042127]; regulation of hair follicle development [GO:0051797]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; response to transforming growth factor beta [GO:0071559]; sebaceous gland development [GO:0048733]; secondary palate development [GO:0062009]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somite rostral/caudal axis specification [GO:0032525]; spermatogenesis [GO:0007283]; tissue morphogenesis [GO:0048729]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; nuclear inner membrane [GO:0005637]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]; co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; I-SMAD binding [GO:0070411]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; BMP signaling pathway [GO:0030509]; bone development [GO:0060348]; cardiac muscle cell proliferation [GO:0060038]; cartilage development [GO:0051216]; cellular response to BMP stimulus [GO:0071773]; cellular response to organic cyclic compound [GO:0071407]; embryonic pattern specification [GO:0009880]; gamete generation [GO:0007276]; hindbrain development [GO:0030902]; homeostatic process [GO:0042592]; inflammatory response [GO:0006954]; MAPK cascade [GO:0000165]; mesodermal cell fate commitment [GO:0001710]; midbrain development [GO:0030901]; negative regulation of cell population proliferation [GO:0008285]; osteoblast fate commitment [GO:0002051]; positive regulation of cartilage development [GO:0061036]; positive regulation of cell differentiation [GO:0045597]; positive regulation of gene expression [GO:0010628]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; protein phosphorylation [GO:0006468]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]	anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; brainstem development [GO:0003360]; branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac septum development [GO:0003279]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular iron ion homeostasis [GO:0006879]; cellular response to glucose stimulus [GO:0071333]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; endocardial cell differentiation [GO:0060956]; endoderm development [GO:0007492]; endothelial cell activation [GO:0042118]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; ERK1 and ERK2 cascade [GO:0070371]; female gonad development [GO:0008585]; female gonad morphogenesis [GO:0061040]; formation of anatomical boundary [GO:0048859]; gastrulation [GO:0007369]; gastrulation with mouth forming second [GO:0001702]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; male gonad development [GO:0008584]; mesendoderm development [GO:0048382]; mesoderm development [GO:0007498]; metanephric mesenchyme morphogenesis [GO:0072133]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cardiac myofibril assembly [GO:1905305]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural crest cell differentiation [GO:0014033]; neuron fate commitment [GO:0048663]; osteoblast differentiation [GO:0001649]; outflow tract septum morphogenesis [GO:0003148]; ovarian follicle development [GO:0001541]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell proliferation involved in heart valve morphogenesis [GO:0003251]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of luteinizing hormone secretion [GO:0033686]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; protein homotrimerization [GO:0070207]; regulation of binding [GO:0051098]; regulation of cell population proliferation [GO:0042127]; regulation of hair follicle development [GO:0051797]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta2 production [GO:0032909]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to hypoxia [GO:0001666]; response to transforming growth factor beta [GO:0071559]; sebaceous gland development [GO:0048733]; secondary palate development [GO:0062009]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somite rostral/caudal axis specification [GO:0032525]; spermatogenesis [GO:0007283]; tissue morphogenesis [GO:0048729]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; wound healing [GO:0042060]	BMP signaling pathway [GO:0030509]; bone development [GO:0060348]; cardiac muscle cell proliferation [GO:0060038]; cartilage development [GO:0051216]; cellular response to BMP stimulus [GO:0071773]; cellular response to organic cyclic compound [GO:0071407]; embryonic pattern specification [GO:0009880]; gamete generation [GO:0007276]; hindbrain development [GO:0030902]; homeostatic process [GO:0042592]; inflammatory response [GO:0006954]; MAPK cascade [GO:0000165]; mesodermal cell fate commitment [GO:0001710]; midbrain development [GO:0030901]; negative regulation of cell population proliferation [GO:0008285]; osteoblast fate commitment [GO:0002051]; positive regulation of cartilage development [GO:0061036]; positive regulation of cell differentiation [GO:0045597]; positive regulation of gene expression [GO:0010628]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; protein phosphorylation [GO:0006468]; regulation of transcription by RNA polymerase II [GO:0006357]; response to drug [GO:0042493]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]	activin responsive factor complex [GO:0032444]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; RNA polymerase II transcription factor complex [GO:0090575]; SMAD protein complex [GO:0071141]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; nuclear inner membrane [GO:0005637]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; collagen binding [GO:0005518]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; filamin binding [GO:0031005]; identical protein binding [GO:0042802]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; molecular function regulator [GO:0098772]; protein homodimerization activity [GO:0042803]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; R-SMAD binding [GO:0070412]; SMAD binding [GO:0046332]; sulfate binding [GO:0043199]; transcription coregulator activity [GO:0003712]; transcription regulatory region DNA binding [GO:0044212]; transforming growth factor beta receptor, common-partner cytoplasmic mediator activity [GO:0030616]	co-SMAD binding [GO:0070410]; DEAD/H-box RNA helicase binding [GO:0017151]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; I-SMAD binding [GO:0070411]; metal ion binding [GO:0046872]; primary miRNA binding [GO:0070878]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]
d3qt2e__d1iara___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]	centriolar satellite [GO:0034451]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; interleukin-4 receptor activity [GO:0004913]; cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; immune response [GO:0006955]; immunoglobulin mediated immune response [GO:0016064]; negative regulation of T-helper 1 cell differentiation [GO:0045626]; ovulation [GO:0030728]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; production of molecular mediator involved in inflammatory response [GO:0002532]; regulation of cell population proliferation [GO:0042127]; response to estrogen [GO:0043627]; response to odorant [GO:1990834]; signal transduction [GO:0007165]	cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]	cytokine-mediated signaling pathway [GO:0019221]; defense response to protozoan [GO:0042832]; immune response [GO:0006955]; immunoglobulin mediated immune response [GO:0016064]; negative regulation of T-helper 1 cell differentiation [GO:0045626]; ovulation [GO:0030728]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of macrophage activation [GO:0043032]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; production of molecular mediator involved in inflammatory response [GO:0002532]; regulation of cell population proliferation [GO:0042127]; response to estrogen [GO:0043627]; response to odorant [GO:1990834]; signal transduction [GO:0007165]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	centriolar satellite [GO:0034451]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]	interleukin-4 receptor activity [GO:0004913]
d3qt3a__d4txta___1			Firmicutes	Firmicutes	catalytic activity [GO:0003824]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]			catalytic activity [GO:0003824]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d3qt9a__d5m7ia___1			Firmicutes	Firmicutes	catalytic activity [GO:0003824]	catalytic activity [GO:0003824]					catalytic activity [GO:0003824]	catalytic activity [GO:0003824]
d3qtfa__d1z5ba3__1	Metazoa		Chordata	Crenarchaeota	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]		ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; identical protein binding [GO:0042802]
d3qu2b__d1u7pd___1		Metazoa	Bacteroidetes	Chordata	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; fructosamine metabolic process [GO:0030389]		fructosamine metabolic process [GO:0030389]			metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]
d3qu2c__d2r8ye___1			Bacteroidetes	Proteobacteria	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]			metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d3qu2d__d4y2ta1__1		Metazoa	Bacteroidetes	Chordata	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3qu3c__d2stta___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer sequence-specific DNA binding [GO:0001158]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; immunoglobulin mediated immune response [GO:0016064]; interferon-alpha production [GO:0032607]; interferon-beta production [GO:0032608]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of adaptive immune response [GO:0002819]; regulation of gene expression [GO:0010468]; regulation of innate immune response [GO:0045088]; regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034124]; regulation of MyD88-independent toll-like receptor signaling pathway [GO:0034127]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	defense response to virus [GO:0051607]; immune system process [GO:0002376]; immunoglobulin mediated immune response [GO:0016064]; interferon-alpha production [GO:0032607]; interferon-beta production [GO:0032608]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; regulation of adaptive immune response [GO:0002819]; regulation of gene expression [GO:0010468]; regulation of innate immune response [GO:0045088]; regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034124]; regulation of MyD88-independent toll-like receptor signaling pathway [GO:0034127]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer sequence-specific DNA binding [GO:0001158]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3qu4b__d2i54c___1			Bacteroidetes		metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]; GDP-mannose biosynthetic process [GO:0009298]		GDP-mannose biosynthetic process [GO:0009298]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]
d3qu4c__d4ygqa1__1			Bacteroidetes	Euryarchaeota	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]					metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3qu7a__d5aiba1__1		Metazoa	Bacteroidetes	Chordata	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3qu9a1_d3ewib___1		Metazoa	Bacteroidetes	Chordata	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	nucleus [GO:0005634]; N-acylneuraminate cytidylyltransferase activity [GO:0008781]; CMP-N-acetylneuraminate biosynthetic process [GO:0006055]; N-acetylneuraminate metabolic process [GO:0006054]		CMP-N-acetylneuraminate biosynthetic process [GO:0006055]; N-acetylneuraminate metabolic process [GO:0006054]		nucleus [GO:0005634]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	N-acylneuraminate cytidylyltransferase activity [GO:0008781]
d3quba__d3umgd___1			Bacteroidetes	Actinobacteria	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	(S)-2-haloacid dehalogenase activity [GO:0018784]					metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	(S)-2-haloacid dehalogenase activity [GO:0018784]
d3quca1_d1z5ua___1			Bacteroidetes	Proteobacteria	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]				outer membrane-bounded periplasmic space [GO:0030288]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]
d3quga__d3qzoa___1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme binding [GO:0020037]	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]			cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	cell wall [GO:0005618]; extracellular region [GO:0005576]	heme binding [GO:0020037]	metal ion binding [GO:0046872]
d3qugb__d3s48b___1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme binding [GO:0020037]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3quhb__d3szkc___1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme binding [GO:0020037]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3qusb__d1m34n___1			Firmicutes	Proteobacteria	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; tetrahydrofolate interconversion [GO:0035999]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	tetrahydrofolate interconversion [GO:0035999]	nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d3quxd2_d4nhud2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d3quyc1_d1fg2h___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3quyd1_d1deee1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	pathogenesis [GO:0009405]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	IgG binding [GO:0019864]
d3quzb__d4x6dh2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3quzd1_d5e5mc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3quzd2_d1tzia1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]
d3qv4c__d2l47a___1	Metazoa		Chordata		extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; cytolysis by virus of host cell [GO:0044659]; peptidoglycan catabolic process [GO:0009253]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cytolysis by virus of host cell [GO:0044659]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]		N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]
d3qv8d2_d1a5uh1__1		Metazoa		Chordata	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]; positive regulation of sprouting angiogenesis [GO:1903672]		positive regulation of sprouting angiogenesis [GO:1903672]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; potassium ion binding [GO:0030955]; pyruvate kinase activity [GO:0004743]
d3qvda1_d2fl0c___1			Euryarchaeota	Proteobacteria	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3qvda1_d4toeg___1			Euryarchaeota	Proteobacteria	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3qvdb1_d5ls9i___1			Euryarchaeota	Euryarchaeota	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]
d3qvdd1_d1qghk___1			Euryarchaeota	Firmicutes	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3qvdd1_d2jd61___1			Euryarchaeota	Euryarchaeota	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d3qvde1_d1kgoa___1			Euryarchaeota	Actinobacteria	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		ribonucleoside-diphosphate reductase complex [GO:0005971]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3qvde1_d2vxii___1			Euryarchaeota	Proteobacteria	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3qvdf1_d2fg8e___1		Metazoa	Euryarchaeota	Chordata	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]		cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]		autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]	iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3qvgb1_d1t2vb1__1	Metazoa	Metazoa	Chordata	Chordata	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; cerebellum morphogenesis [GO:0021587]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; voluntary musculoskeletal movement [GO:0050882]	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; gamma-tubulin ring complex [GO:0008274]; lateral element [GO:0000800]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151]; androgen receptor binding [GO:0050681]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; androgen receptor signaling pathway [GO:0030521]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to indole-3-methanol [GO:0071681]; cellular response to tumor necrosis factor [GO:0071356]; centrosome cycle [GO:0007098]; chordate embryonic development [GO:0043009]; chromosome segregation [GO:0007059]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; fatty acid biosynthetic process [GO:0006633]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of centriole replication [GO:0046600]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of DNA repair [GO:0045739]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of histone H4-K20 methylation [GO:0070512]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; response to estrogen [GO:0043627]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	base-excision repair [GO:0006284]; cerebellum morphogenesis [GO:0021587]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; voluntary musculoskeletal movement [GO:0050882]	androgen receptor signaling pathway [GO:0030521]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to indole-3-methanol [GO:0071681]; cellular response to tumor necrosis factor [GO:0071356]; centrosome cycle [GO:0007098]; chordate embryonic development [GO:0043009]; chromosome segregation [GO:0007059]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; fatty acid biosynthetic process [GO:0006633]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2/M transition checkpoint [GO:0044818]; negative regulation of centriole replication [GO:0046600]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of DNA repair [GO:0045739]; positive regulation of gene expression [GO:0010628]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of histone H4-K16 acetylation [GO:2000620]; positive regulation of histone H4-K20 methylation [GO:0070512]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; postreplication repair [GO:0006301]; protein autoubiquitination [GO:0051865]; protein deubiquitination [GO:0016579]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; response to estrogen [GO:0043627]; response to ionizing radiation [GO:0010212]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	BRCA1-A complex [GO:0070531]; BRCA1-BARD1 complex [GO:0031436]; chromosome [GO:0005694]; cytoplasm [GO:0005737]; gamma-tubulin ring complex [GO:0008274]; lateral element [GO:0000800]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ribonucleoprotein complex [GO:1990904]; ubiquitin ligase complex [GO:0000151]	enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]	androgen receptor binding [GO:0050681]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase binding [GO:0070063]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d3qvyb__d2yl0a___1				Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3qvzb__d2ykza___1				Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3qw0a__d3iq6a___1				Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3qw1a__d5agfa___1				Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3qw1d__d1cpqa___1				Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3qw8a__d1cqrb___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	negative regulation of neurotransmitter secretion [GO:0046929]	cellular response to nitric oxide [GO:0071732]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; positive regulation of oxidative stress-induced cell death [GO:1903209]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3qwfa__d2bd0a1__1	Fungi		Ascomycota	Chlorobi	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]				cytoplasm [GO:0005737]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3qwfb__d5gudc2__1	Fungi		Ascomycota	Actinobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]			nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d3qwfd__d5g4la1__1	Fungi		Ascomycota	Firmicutes	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]					nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3qwfg__d2cmda1__1	Fungi		Ascomycota	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]
d3qwha__d2nsda___1	Fungi		Ascomycota	Actinobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d3qwib__d1ldnb1__1	Fungi		Ascomycota	Firmicutes	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d3qwob1_d43c9c___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qwob2_d4ffwc1__1		Metazoa		Chordata		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]		cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3qwol2_d3fb6b1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qx1a1_d5chwf2__1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3qx1b1_d2d5gb1__1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	beta-catenin destruction complex [GO:0030877]; cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]; apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein homooligomerization [GO:0051260]; Wnt signaling pathway [GO:0016055]	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein homooligomerization [GO:0051260]; Wnt signaling pathway [GO:0016055]	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]	beta-catenin destruction complex [GO:0030877]; cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]	armadillo repeat domain binding [GO:0070016]; beta-catenin binding [GO:0008013]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; signaling receptor binding [GO:0005102]
d3qx7a1_d1rqna___1			Bacteroidetes	Firmicutes	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]; organic phosphonate catabolic process [GO:0019700]		organic phosphonate catabolic process [GO:0019700]			metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	magnesium ion binding [GO:0000287]; phosphonoacetaldehyde hydrolase activity [GO:0050194]
d3qx9a__d4krfa2__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mRNA cap binding complex [GO:0005845]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]; core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; endoribonuclease activity [GO:0004521]; endoribonuclease activity, cleaving miRNA-paired mRNA [GO:0090624]; endoribonuclease activity, cleaving siRNA-paired mRNA [GO:0070551]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA cap binding [GO:0098808]; protein C-terminus binding [GO:0008022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; translation initiation factor activity [GO:0003743]; gene silencing by RNA [GO:0031047]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; mRNA cleavage involved in gene silencing by siRNA [GO:0090625]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of gene expression [GO:0010629]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene silencing by miRNA [GO:0060964]; RNA secondary structure unwinding [GO:0010501]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; translation [GO:0006412]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]; core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded RNA binding [GO:0003727]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; negative regulation of angiogenesis [GO:0016525]; negative regulation of gene expression [GO:0010629]; nuclear-transcribed mRNA catabolic process [GO:0000956]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA secondary structure unwinding [GO:0010501]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	gene silencing by RNA [GO:0031047]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; mRNA cleavage involved in gene silencing by siRNA [GO:0090625]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of gene expression [GO:0010629]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene silencing by miRNA [GO:0060964]; RNA secondary structure unwinding [GO:0010501]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; translation [GO:0006412]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; negative regulation of angiogenesis [GO:0016525]; negative regulation of gene expression [GO:0010629]; nuclear-transcribed mRNA catabolic process [GO:0000956]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA secondary structure unwinding [GO:0010501]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mRNA cap binding complex [GO:0005845]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]	core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; endoribonuclease activity [GO:0004521]; endoribonuclease activity, cleaving miRNA-paired mRNA [GO:0090624]; endoribonuclease activity, cleaving siRNA-paired mRNA [GO:0070551]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA cap binding [GO:0098808]; protein C-terminus binding [GO:0008022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; translation initiation factor activity [GO:0003743]	core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; single-stranded RNA binding [GO:0003727]
d3qx9c__d4g0ya1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mRNA cap binding complex [GO:0005845]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]; core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; endoribonuclease activity [GO:0004521]; endoribonuclease activity, cleaving miRNA-paired mRNA [GO:0090624]; endoribonuclease activity, cleaving siRNA-paired mRNA [GO:0070551]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA cap binding [GO:0098808]; protein C-terminus binding [GO:0008022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; translation initiation factor activity [GO:0003743]; gene silencing by RNA [GO:0031047]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; mRNA cleavage involved in gene silencing by siRNA [GO:0090625]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of gene expression [GO:0010629]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene silencing by miRNA [GO:0060964]; RNA secondary structure unwinding [GO:0010501]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; translation [GO:0006412]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; adaxial/abaxial pattern specification [GO:0009955]; adventitious root development [GO:0048830]; auxin metabolic process [GO:0009850]; cell differentiation [GO:0030154]; defense response to virus [GO:0051607]; gene silencing by miRNA [GO:0035195]; innate immune response [GO:0045087]; leaf morphogenesis [GO:0009965]; leaf proximal/distal pattern formation [GO:0010589]; leaf vascular tissue pattern formation [GO:0010305]; posttranscriptional gene silencing [GO:0016441]; regulation of translation [GO:0006417]; response to auxin [GO:0009733]; response to far red light [GO:0010218]; viral gene silencing in virus induced gene silencing [GO:0060145]; viral process [GO:0016032]; virus induced gene silencing [GO:0009616]	gene silencing by RNA [GO:0031047]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; mRNA cleavage involved in gene silencing by siRNA [GO:0090625]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of gene expression [GO:0010629]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA mediated inhibition of translation [GO:1905618]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; posttranscriptional gene silencing by RNA [GO:0035194]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene silencing by miRNA [GO:0060964]; RNA secondary structure unwinding [GO:0010501]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; translation [GO:0006412]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	adaxial/abaxial pattern specification [GO:0009955]; adventitious root development [GO:0048830]; auxin metabolic process [GO:0009850]; cell differentiation [GO:0030154]; defense response to virus [GO:0051607]; gene silencing by miRNA [GO:0035195]; innate immune response [GO:0045087]; leaf morphogenesis [GO:0009965]; leaf proximal/distal pattern formation [GO:0010589]; leaf vascular tissue pattern formation [GO:0010305]; posttranscriptional gene silencing [GO:0016441]; regulation of translation [GO:0006417]; response to auxin [GO:0009733]; response to far red light [GO:0010218]; viral gene silencing in virus induced gene silencing [GO:0060145]; viral process [GO:0016032]; virus induced gene silencing [GO:0009616]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mRNA cap binding complex [GO:0005845]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; polysome [GO:0005844]; ribonucleoprotein complex [GO:1990904]; RISC complex [GO:0016442]; RISC-loading complex [GO:0070578]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	core promoter binding [GO:0001047]; double-stranded RNA binding [GO:0003725]; endoribonuclease activity [GO:0004521]; endoribonuclease activity, cleaving miRNA-paired mRNA [GO:0090624]; endoribonuclease activity, cleaving siRNA-paired mRNA [GO:0070551]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA cap binding [GO:0098808]; protein C-terminus binding [GO:0008022]; RNA 7-methylguanosine cap binding [GO:0000340]; RNA binding [GO:0003723]; RNA polymerase II complex binding [GO:0000993]; single-stranded RNA binding [GO:0003727]; siRNA binding [GO:0035197]; translation initiation factor activity [GO:0003743]	endoribonuclease activity [GO:0004521]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]
d3qxed__d1ahjd___1				Actinobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d3qxed__d4zgjf___1				Proteobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d3qxef__d4fm4p___1				Proteobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d3qxib__d2zl3i___1			Actinobacteria	Proteobacteria	catalytic activity [GO:0003824]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]		cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	catalytic activity [GO:0003824]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]
d3qxta__d2bdnh1__1		Metazoa		Chordata		cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR2 chemokine receptor binding [GO:0031727]; chemokine activity [GO:0008009]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; astrocyte cell migration [GO:0043615]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular homeostasis [GO:0019725]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; helper T cell extravasation [GO:0035684]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of natural killer cell chemotaxis [GO:2000502]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of calcium ion import [GO:0090280]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of T cell activation [GO:0050870]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; viral genome replication [GO:0019079]		angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; astrocyte cell migration [GO:0043615]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular homeostasis [GO:0019725]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytokine-mediated signaling pathway [GO:0019221]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; helper T cell extravasation [GO:0035684]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lymphocyte chemotaxis [GO:0048247]; macrophage chemotaxis [GO:0048246]; MAPK cascade [GO:0000165]; monocyte chemotaxis [GO:0002548]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of natural killer cell chemotaxis [GO:2000502]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; neutrophil chemotaxis [GO:0030593]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of calcium ion import [GO:0090280]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of T cell activation [GO:0050870]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell shape [GO:0008360]; response to bacterium [GO:0009617]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; viral genome replication [GO:0019079]		cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		CCR2 chemokine receptor binding [GO:0031727]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]
d3qxud__d3c6sg1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qxvb__d5u2ve2__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3qxwd__d1q0xl1__1		Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		
d3qxwe__d1lp9i1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3qy4a__d1l74a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3qyda__d3n7ma2__1	Viridiplantae		Streptophyta	Firmicutes	serine-type endopeptidase inhibitor activity [GO:0004867]	extracellular region [GO:0005576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]		negative regulation of neurotransmitter secretion [GO:0046929]; pathogenesis [GO:0009405]		extracellular region [GO:0005576]	serine-type endopeptidase inhibitor activity [GO:0004867]	metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; zinc ion binding [GO:0008270]
d3qygb__d3a8mb___1				Actinobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d3qygh__d3a8hb___1				Actinobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d3qyhd__d3x26b___1				Actinobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d3qyoa__d5uioe___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]	cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d3qypb1_d4nv0b___1		Metazoa	Bacteroidetes	Arthropoda	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]; dephosphorylation [GO:0016311]; guanosine-containing compound catabolic process [GO:1901069]; nucleotide metabolic process [GO:0009117]; ribonucleoside monophosphate catabolic process [GO:0009158]		dephosphorylation [GO:0016311]; guanosine-containing compound catabolic process [GO:1901069]; nucleotide metabolic process [GO:0009117]; ribonucleoside monophosphate catabolic process [GO:0009158]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]	5'-nucleotidase activity [GO:0008253]; magnesium ion binding [GO:0000287]; nucleotidase activity [GO:0008252]; nucleotide binding [GO:0000166]
d3qysa__d4xkma___1			Actinobacteria	Bacteroidetes	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d3qz9b__d1v29b___1				Firmicutes		nitrile hydratase activity [GO:0018822]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				nitrile hydratase activity [GO:0018822]; transition metal ion binding [GO:0046914]
d3qz9f__d1ugpb___1				Actinobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; nitrile hydratase activity [GO:0018822]; transition metal ion binding [GO:0046914]; nitrile catabolic process [GO:0050899]		nitrile catabolic process [GO:0050899]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; nitrile hydratase activity [GO:0018822]; transition metal ion binding [GO:0046914]
d3qz9h__d2zcfb___1				Actinobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d3qzeb__d1n8fd___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; 3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; identical protein binding [GO:0042802]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	3-deoxy-7-phosphoheptulonate synthase activity [GO:0003849]; identical protein binding [GO:0042802]
d3qzja__d1ifba___1		Metazoa		Chordata		apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]		fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]		apical cortex [GO:0045179]; cytoplasm [GO:0005737]; microvillus [GO:0005902]; plasma membrane [GO:0005886]		fatty acid binding [GO:0005504]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]
d3qzob__d3rtla1__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]	cell wall [GO:0005618]; extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	metal ion binding [GO:0046872]	heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]
d3qzpb1_d3vuaf___1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme binding [GO:0020037]			cell wall [GO:0005618]; extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	metal ion binding [GO:0046872]	heme binding [GO:0020037]
d3qzrb__d5dj7a___1				Actinobacteria	cysteine-type endopeptidase activity [GO:0004197]	serine-type endopeptidase activity [GO:0004252]					cysteine-type endopeptidase activity [GO:0004197]	serine-type endopeptidase activity [GO:0004252]
d3qzta__d5fbxa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]
d3qzua__d4kjxa___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]		lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	triglyceride lipase activity [GO:0004806]
d3qzua__d5ctaa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d3qzub__d1t4ma___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d3qzwb1_d5bvje2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3qzwe1_d4nwul1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3qzwh__d1rjye1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3r06a1_d3ux9b1__1		Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]		adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]
d3r06a2_d5u17g1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3r06c1_d4xbpf1__1												
d3r06c2_d1egjl1__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3r06l2_d5esvb1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3r0ed__d2dpfc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta		carbohydrate binding [GO:0030246]						carbohydrate binding [GO:0030246]
d3r0ed__d4h3oa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta								
d3r0fb__d5gswb___1					cysteine-type endopeptidase activity [GO:0004197]	cysteine-type endopeptidase activity [GO:0004197]					cysteine-type endopeptidase activity [GO:0004197]	cysteine-type endopeptidase activity [GO:0004197]
d3r0ld__d2azza___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]; bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	extracellular region [GO:0005576]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]	bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]
d3r0mb__d1h3pl2__1		Metazoa		Chordata								
d3r0pf__d3lmeb1__1				Proteobacteria								
d3r0qa__d1t43a___1	Viridiplantae		Streptophyta	Proteobacteria	cytosol [GO:0005829]; [myelin basic protein]-arginine N-methyltransferase activity [GO:0016277]; histone-arginine N-methyltransferase activity [GO:0008469]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; vegetative to reproductive phase transition of meristem [GO:0010228]	nucleic acid binding [GO:0003676]; protein methyltransferase activity [GO:0008276]; protein-(glutamine-N5) methyltransferase activity [GO:0102559]; protein-glutamine N-methyltransferase activity [GO:0036009]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; peptidyl-glutamine methylation [GO:0018364]; protein methylation [GO:0006479]; regulation of gene expression [GO:0010468]; translational termination [GO:0006415]	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; vegetative to reproductive phase transition of meristem [GO:0010228]	peptidyl-glutamine methylation [GO:0018364]; protein methylation [GO:0006479]; regulation of gene expression [GO:0010468]; translational termination [GO:0006415]	cytosol [GO:0005829]		[myelin basic protein]-arginine N-methyltransferase activity [GO:0016277]; histone-arginine N-methyltransferase activity [GO:0008469]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]	nucleic acid binding [GO:0003676]; protein-(glutamine-N5) methyltransferase activity [GO:0102559]; protein-glutamine N-methyltransferase activity [GO:0036009]; protein methyltransferase activity [GO:0008276]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d3r0wb__d1smea___1				Apicomplexa	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]				vacuole [GO:0005773]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]
d3r0wb__d2aofa___1					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3r0ya__d2er9e___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]
d3r18a2_d3n42f2__1	Metazoa		Chordata		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	host cell cytoplasm [GO:0030430]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	host cell cytoplasm [GO:0030430]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; virion membrane [GO:0055036]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3r19a1_d1ogpf2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	chlorophyll metabolic process [GO:0015994]; nitrate assimilation [GO:0042128]; response to sulfur dioxide [GO:0010477]; sulfur compound metabolic process [GO:0006790]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]
d3r1ra1_d1peoa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	ribonucleoside-diphosphate reductase complex [GO:0005971]; ATP binding [GO:0005524]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ribonucleoside-diphosphate reductase complex [GO:0005971]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ATP binding [GO:0005524]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3r1ra2_d4mtja___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	catalytic activity [GO:0003824]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	catalytic activity [GO:0003824]
d3r1rb2_d1qhmb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; membrane [GO:0016020]; formate C-acetyltransferase activity [GO:0008861]; glucose metabolic process [GO:0006006]; threonine catabolic process [GO:0006567]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	glucose metabolic process [GO:0006006]; threonine catabolic process [GO:0006567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cytosol [GO:0005829]; membrane [GO:0016020]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	formate C-acetyltransferase activity [GO:0008861]
d3r25a1_d4zcwa1__1		Metazoa	Proteobacteria	Chordata	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cellular amino acid catabolic process [GO:0009063]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3r25d2_d1sjdc1__1			Proteobacteria	Actinobacteria	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	cellular amino acid catabolic process [GO:0009063]	menaquinone biosynthetic process [GO:0009234]			magnesium ion binding [GO:0000287]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3r25f2_d1jdfb1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	cellular amino acid catabolic process [GO:0009063]	D-glucarate catabolic process [GO:0042838]			magnesium ion binding [GO:0000287]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3r2ea1_d2dtte___1			Proteobacteria	Euryarchaeota	dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	metal ion binding [GO:0046872]	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydroneopterin aldolase activity [GO:0004150]	metal ion binding [GO:0046872]
d3r2ha__d1xvcd___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3r2jd__d3kl2b1__1				Actinobacteria	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]					hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]
d3r2ka__d1bfrk___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3r2la__d1vele___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3r2ma__d1kgna___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3r2nb__d1wkqb___1			Actinobacteria	Firmicutes	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]	guanine deaminase activity [GO:0008892]; guanosine deaminase activity [GO:0047974]; zinc ion binding [GO:0008270]; guanine catabolic process [GO:0006147]; purine nucleoside catabolic process [GO:0006152]		guanine catabolic process [GO:0006147]; purine nucleoside catabolic process [GO:0006152]			cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]	guanine deaminase activity [GO:0008892]; guanosine deaminase activity [GO:0047974]; zinc ion binding [GO:0008270]
d3r2nd1_d3v4ja___1		Metazoa	Actinobacteria	Chordata	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]		base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]		apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]	cytidine deaminase activity [GO:0004126]; zinc ion binding [GO:0008270]	cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3r2oa__d3bknl___1			Proteobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3r31b__d1nzxg___1		Metazoa	Proteobacteria	Chordata	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glycine betaine biosynthetic process from choline [GO:0019285]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3r32a__d5szvc___1			Actinobacteria	Proteobacteria	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	thiolester hydrolase activity [GO:0016790]					4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	thiolester hydrolase activity [GO:0016790]
d3r32b__d2h4ud2__1		Metazoa	Actinobacteria	Chordata	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]; acyl-CoA hydrolase activity [GO:0047617]; acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]		acyl-CoA metabolic process [GO:0006637]; negative regulation of cold-induced thermogenesis [GO:0120163]; protein homotetramerization [GO:0051289]		cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; spindle [GO:0005819]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	acyl-CoA hydrolase activity [GO:0047617]
d3r33a__d1u71a___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	cytosol [GO:0005829]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3r34a__d1wlvg___1			Actinobacteria	Deinococcus-Thermus	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	thiolester hydrolase activity [GO:0016790]					4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	thiolester hydrolase activity [GO:0016790]
d3r34a__d4zw0c___1			Actinobacteria	Proteobacteria	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3r35b__d5kl9c___1			Actinobacteria	Proteobacteria	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	plasma membrane [GO:0005886]; acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]; lipid metabolic process [GO:0006629]		lipid metabolic process [GO:0006629]		plasma membrane [GO:0005886]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]
d3r36a__d4zrba___1			Actinobacteria	Firmicutes	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	acyl-CoA hydrolase activity [GO:0047617]					4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	acyl-CoA hydrolase activity [GO:0047617]
d3r37a__d5hmca1__1			Actinobacteria	Actinobacteria	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]						4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	
d3r39b__d3t96b___1		Metazoa		Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3r3aa__d3azbg___1			Actinobacteria	Apicomplexa	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]			4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	hydro-lyase activity [GO:0016836]
d3r3aa__d4k4bb___1			Actinobacteria	Proteobacteria	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]; menaquinone biosynthetic process [GO:0009234]		menaquinone biosynthetic process [GO:0009234]		cytosol [GO:0005829]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity [GO:0061522]; CoA hydrolase activity [GO:0016289]; hydrolase activity [GO:0016787]
d3r3da__d1wn3e___1			Actinobacteria	Deinococcus-Thermus	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	thiolester hydrolase activity [GO:0016790]					4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	thiolester hydrolase activity [GO:0016790]
d3r3da__d3azax___1			Actinobacteria	Apicomplexa	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]			4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	hydro-lyase activity [GO:0016836]
d3r3ha__d3tpza___1			Proteobacteria	Proteobacteria	O-methyltransferase activity [GO:0008171]	cytosol [GO:0005829]; 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity [GO:0052908]; double-stranded DNA binding [GO:0003690]; mRNA binding [GO:0003729]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]; rRNA binding [GO:0019843]; response to antibiotic [GO:0046677]; ribosomal small subunit assembly [GO:0000028]; rRNA base methylation [GO:0070475]; rRNA methylation [GO:0031167]; rRNA processing [GO:0006364]		response to antibiotic [GO:0046677]; ribosomal small subunit assembly [GO:0000028]; rRNA base methylation [GO:0070475]; rRNA methylation [GO:0031167]; rRNA processing [GO:0006364]		cytosol [GO:0005829]	O-methyltransferase activity [GO:0008171]	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity [GO:0052908]; double-stranded DNA binding [GO:0003690]; mRNA binding [GO:0003729]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]; rRNA binding [GO:0019843]
d3r3ja1_d1c1da2__1			Apicomplexa	Actinobacteria	apicoplast [GO:0020011]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]; cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	apicoplast [GO:0020011]; cytosol [GO:0005829]		glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d3r3ja1_d4fooa1__1			Apicomplexa	Proteobacteria	apicoplast [GO:0020011]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]; cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	apicoplast [GO:0020011]; cytosol [GO:0005829]	cytosol [GO:0005829]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d3r3jb2_d1pwxb___1			Apicomplexa	Proteobacteria	apicoplast [GO:0020011]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]; cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]		cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]		apicoplast [GO:0020011]; cytosol [GO:0005829]		glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]	
d3r3jd1_d2yfhf1__1			Apicomplexa	Proteobacteria	apicoplast [GO:0020011]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]; cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	glutamate biosynthetic process [GO:0006537]	apicoplast [GO:0020011]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]
d3r3je1_d1b3bd2__1			Apicomplexa	Thermotogae	apicoplast [GO:0020011]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]; cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	cellular amino acid metabolic process [GO:0006520]	apicoplast [GO:0020011]; cytosol [GO:0005829]		glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d3r3je2_d4hx5d1__1		Metazoa	Apicomplexa	Chordata	apicoplast [GO:0020011]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]; cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	apicoplast [GO:0020011]; cytosol [GO:0005829]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d3r3jf1_d3etee1__1		Metazoa	Apicomplexa	Chordata	apicoplast [GO:0020011]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]; cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cellular amino acid metabolic process [GO:0006520]; glutamate biosynthetic process [GO:0006537]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	apicoplast [GO:0020011]; cytosol [GO:0005829]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d3r3oa__d1ihza___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3r3sa__d1q7bc___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	biotin biosynthetic process [GO:0009102]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; oxidation-reduction process [GO:0055114]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3r3sc__d1gcoa___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; oxidation-reduction process [GO:0055114]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]; sporulation resulting in formation of a cellular spore [GO:0030435]	oxidation-reduction process [GO:0055114]	sporulation resulting in formation of a cellular spore [GO:0030435]			metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	glucose 1-dehydrogenase [NAD(P)] activity [GO:0047936]
d3r3ua1_d1qlwb___1			Proteobacteria	Proteobacteria	haloacetate dehalogenase activity [GO:0018785]						haloacetate dehalogenase activity [GO:0018785]	
d3r3zc1_d2dhea___1			Proteobacteria	Proteobacteria	haloacetate dehalogenase activity [GO:0018785]	haloalkane dehalogenase activity [GO:0018786]; 1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]		1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]			haloacetate dehalogenase activity [GO:0018785]	haloalkane dehalogenase activity [GO:0018786]
d3r41a1_d1qj4a___1		Viridiplantae	Proteobacteria	Streptophyta	haloacetate dehalogenase activity [GO:0018785]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]					haloacetate dehalogenase activity [GO:0018785]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]
d3r45b__d3leld___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3r4bb__d4y3ma___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3r4ca1_d3wkba1__1		Metazoa	Bacteroidetes	Chordata	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3r4da2_d1p6fa1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary membrane [GO:0060170]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lateral plasma membrane [GO:0016328]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; actin binding [GO:0003779]; bile acid transmembrane transporter activity [GO:0015125]; calmodulin binding [GO:0005516]; filamin binding [GO:0031005]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; Toll-like receptor binding [GO:0035325]; virus receptor activity [GO:0001618]; bile acid and bile salt transport [GO:0015721]; blood vessel development [GO:0001568]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; common myeloid progenitor cell proliferation [GO:0035726]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; insulin catabolic process [GO:1901143]; insulin receptor internalization [GO:0038016]; negative regulation of bone resorption [GO:0045779]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of vascular permeability [GO:0043116]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of vasculogenesis [GO:2001214]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell growth [GO:0001558]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell migration [GO:0010594]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of homophilic cell adhesion [GO:1903385]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of sprouting angiogenesis [GO:1903670]; wound healing, spreading of cells [GO:0044319]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; SWI/SNF complex [GO:0016514]; cellular defense response [GO:0006968]; natural killer cell activation [GO:0030101]; regulation of immune response [GO:0050776]; regulation of natural killer cell mediated cytotoxicity [GO:0042269]; signal transduction [GO:0007165]	bile acid and bile salt transport [GO:0015721]; blood vessel development [GO:0001568]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; common myeloid progenitor cell proliferation [GO:0035726]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; insulin catabolic process [GO:1901143]; insulin receptor internalization [GO:0038016]; negative regulation of bone resorption [GO:0045779]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of vascular permeability [GO:0043116]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of vasculogenesis [GO:2001214]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell growth [GO:0001558]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell migration [GO:0010594]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of homophilic cell adhesion [GO:1903385]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of sprouting angiogenesis [GO:1903670]; wound healing, spreading of cells [GO:0044319]	cellular defense response [GO:0006968]; natural killer cell activation [GO:0030101]; regulation of immune response [GO:0050776]; regulation of natural killer cell mediated cytotoxicity [GO:0042269]; signal transduction [GO:0007165]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell surface [GO:0009986]; ciliary membrane [GO:0060170]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lateral plasma membrane [GO:0016328]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; SWI/SNF complex [GO:0016514]	actin binding [GO:0003779]; bile acid transmembrane transporter activity [GO:0015125]; calmodulin binding [GO:0005516]; filamin binding [GO:0031005]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; Toll-like receptor binding [GO:0035325]; virus receptor activity [GO:0001618]	
d3r4da2_d3mrpb1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cell junction [GO:0030054]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary membrane [GO:0060170]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lateral plasma membrane [GO:0016328]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; actin binding [GO:0003779]; bile acid transmembrane transporter activity [GO:0015125]; calmodulin binding [GO:0005516]; filamin binding [GO:0031005]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; Toll-like receptor binding [GO:0035325]; virus receptor activity [GO:0001618]; bile acid and bile salt transport [GO:0015721]; blood vessel development [GO:0001568]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; common myeloid progenitor cell proliferation [GO:0035726]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; insulin catabolic process [GO:1901143]; insulin receptor internalization [GO:0038016]; negative regulation of bone resorption [GO:0045779]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of vascular permeability [GO:0043116]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of vasculogenesis [GO:2001214]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell growth [GO:0001558]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell migration [GO:0010594]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of homophilic cell adhesion [GO:1903385]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of sprouting angiogenesis [GO:1903670]; wound healing, spreading of cells [GO:0044319]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	bile acid and bile salt transport [GO:0015721]; blood vessel development [GO:0001568]; cell-cell junction organization [GO:0045216]; cellular response to insulin stimulus [GO:0032869]; common myeloid progenitor cell proliferation [GO:0035726]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; insulin catabolic process [GO:1901143]; insulin receptor internalization [GO:0038016]; negative regulation of bone resorption [GO:0045779]; negative regulation of cytokine production [GO:0001818]; negative regulation of cytotoxic T cell degranulation [GO:0043318]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of JNK cascade [GO:0046329]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [GO:0002859]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of vascular permeability [GO:0043116]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of vasculogenesis [GO:2001214]; regulation of blood vessel remodeling [GO:0060312]; regulation of cell growth [GO:0001558]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell migration [GO:0010594]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of homophilic cell adhesion [GO:1903385]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of sprouting angiogenesis [GO:1903670]; wound healing, spreading of cells [GO:0044319]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell surface [GO:0009986]; ciliary membrane [GO:0060170]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lateral plasma membrane [GO:0016328]; microvillus membrane [GO:0031528]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	actin binding [GO:0003779]; bile acid transmembrane transporter activity [GO:0015125]; calmodulin binding [GO:0005516]; filamin binding [GO:0031005]; granulocyte colony-stimulating factor receptor binding [GO:0005130]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; Toll-like receptor binding [GO:0035325]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3r4eb1_d1ecqa2__1				Proteobacteria		glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]		D-glucarate catabolic process [GO:0042838]				glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3r4ec1_d1tkka2__1				Firmicutes		metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]		cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]				metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d3r4sa2_d5fzyb___1		Viridiplantae		Streptophyta	extracellular region [GO:0005576]; ganglioside binding [GO:0035594]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; membrane protein proteolysis [GO:0033619]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of neurotransmitter secretion [GO:0046929]	endopeptidase inhibitor activity [GO:0004866]; peptidase activity [GO:0008233]	membrane protein proteolysis [GO:0033619]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of neurotransmitter secretion [GO:0046929]		extracellular region [GO:0005576]		ganglioside binding [GO:0035594]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	endopeptidase inhibitor activity [GO:0004866]; peptidase activity [GO:0008233]
d3r50b__d1ugx.1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]
d3r52b__d4pitb1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d3r52c__d1jac.6__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; IgA binding [GO:0019862]
d3r5ic__d5chrb___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d3r5ta1_d5tcyc1__1			Proteobacteria	Proteobacteria		metal ion binding [GO:0046872]; iron ion transport [GO:0006826]		iron ion transport [GO:0006826]				metal ion binding [GO:0046872]
d3r5ua__d1sxva1__1			Euryarchaeota	Actinobacteria	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular region [GO:0005576]; host cell surface [GO:0044228]; plasma membrane [GO:0005886]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3r5vb__d4qmba___1		Metazoa	Euryarchaeota	Platyhelminthes	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3r5vc__d3sw5b___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3r5vd__d3fq3k___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3r66c1_d4gdka___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	Atg12-Atg5-Atg16 complex [GO:0034274]; autophagosome [GO:0005776]; axoneme [GO:0005930]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; phagocytic vesicle membrane [GO:0030670]; phagophore assembly site membrane [GO:0034045]; aggrephagy [GO:0035973]; antigen processing and presentation of endogenous antigen [GO:0019883]; apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; blood vessel remodeling [GO:0001974]; C-terminal protein lipidation [GO:0006501]; cellular homeostasis [GO:0019725]; cellular response to nitrogen starvation [GO:0006995]; cellular response to nitrosative stress [GO:0071500]; heart contraction [GO:0060047]; macroautophagy [GO:0016236]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative stranded viral RNA replication [GO:0039689]; negative thymic T cell selection [GO:0045060]; otolith development [GO:0048840]; positive regulation by symbiont of host autophagy [GO:0075044]; positive regulation of mucus secretion [GO:0070257]; post-translational protein modification [GO:0043687]; protein lipidation involved in autophagosome assembly [GO:0061739]; regulation of cilium assembly [GO:1902017]; regulation of cytokine secretion involved in immune response [GO:0002739]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to drug [GO:0042493]; response to fungus [GO:0009620]; vasodilation [GO:0042311]; ventricular cardiac muscle cell development [GO:0055015]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	aggrephagy [GO:0035973]; antigen processing and presentation of endogenous antigen [GO:0019883]; apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; blood vessel remodeling [GO:0001974]; cellular homeostasis [GO:0019725]; cellular response to nitrogen starvation [GO:0006995]; cellular response to nitrosative stress [GO:0071500]; C-terminal protein lipidation [GO:0006501]; heart contraction [GO:0060047]; macroautophagy [GO:0016236]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative stranded viral RNA replication [GO:0039689]; negative thymic T cell selection [GO:0045060]; otolith development [GO:0048840]; positive regulation by symbiont of host autophagy [GO:0075044]; positive regulation of mucus secretion [GO:0070257]; post-translational protein modification [GO:0043687]; protein lipidation involved in autophagosome assembly [GO:0061739]; regulation of cilium assembly [GO:1902017]; regulation of cytokine secretion involved in immune response [GO:0002739]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to drug [GO:0042493]; response to fungus [GO:0009620]; vasodilation [GO:0042311]; ventricular cardiac muscle cell development [GO:0055015]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	Atg12-Atg5-Atg16 complex [GO:0034274]; autophagosome [GO:0005776]; axoneme [GO:0005930]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; phagocytic vesicle membrane [GO:0030670]; phagophore assembly site membrane [GO:0034045]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	
d3r6mb1_d1p8za2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3r6mb2_d3bf3a1__1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	tRNA threonylcarbamoyladenosine modification [GO:0002949]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d3r6qa__d1i0aa___1		Metazoa	Firmicutes	Chordata	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]; aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	structural constituent of eye lens [GO:0005212]; arginine biosynthetic process via ornithine [GO:0042450]	aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	arginine biosynthetic process via ornithine [GO:0042450]			aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3r6qd__d1jswa___1			Firmicutes	Proteobacteria	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]; aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; aspartate ammonia-lyase activity [GO:0008797]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; tricarboxylic acid cycle [GO:0006099]	aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; membrane [GO:0016020]	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]	aspartate ammonia-lyase activity [GO:0008797]
d3r6sc1_d1wgpa1__1		Viridiplantae	Actinobacteria	Streptophyta	protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	cell periphery [GO:0071944]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; intracellular cGMP-activated cation channel activity [GO:0005223]; voltage-gated potassium channel activity [GO:0005249]; response to cadmium ion [GO:0046686]	regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	response to cadmium ion [GO:0046686]	protein-DNA complex [GO:0032993]	cell periphery [GO:0071944]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	calmodulin binding [GO:0005516]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; intracellular cGMP-activated cation channel activity [GO:0005223]; voltage-gated potassium channel activity [GO:0005249]
d3r6sd1_d4ft8a1__1			Actinobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	protein-DNA complex [GO:0032993]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3r6sf2_d1hsjb1__1			Actinobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	protein-DNA complex [GO:0032993]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3r6ta__d3lgad___1	Metazoa		Chordata	Euryarchaeota	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	tRNA (m1A) methyltransferase complex [GO:0031515]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	tRNA (m1A) methyltransferase complex [GO:0031515]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]
d3r6vc__d3oced1__1			Firmicutes	Proteobacteria	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]; aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	aspartate ammonia-lyase activity [GO:0008797]; tricarboxylic acid cycle [GO:0006099]	aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]			aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]	aspartate ammonia-lyase activity [GO:0008797]
d3r6vh__d3tv2a___1			Firmicutes	Proteobacteria	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]; aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]		tricarboxylic acid cycle enzyme complex [GO:0045239]	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]	fumarate hydratase activity [GO:0004333]
d3r6vh__d4apbd___1			Firmicutes	Actinobacteria	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]; aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	aspartate metabolic process [GO:0006531]; tricarboxylic acid cycle [GO:0006099]	fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; tricarboxylic acid cycle enzyme complex [GO:0045239]	aspartate ammonia-lyase activity [GO:0008797]; metal ion binding [GO:0046872]	fumarate hydratase activity [GO:0004333]
d3r7cc__d4e0ic___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]; cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; protein import into mitochondrial intermembrane space [GO:0045041]	cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573]; response to lipopolysaccharide [GO:0032496]	cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; protein import into mitochondrial intermembrane space [GO:0045041]	cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	cell [GO:0005623]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]
d3r7da1_d1ekxb1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d3r7da2_d1r0bb1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d3r7da2_d3upda2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d3r7dc1_d4nf2a2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d3r7dc2_d4at1c2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d3r7fa2_d4iv5d1__1			Firmicutes		cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; cellular amino acid metabolic process [GO:0006520]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d3r7fb1_d3e2pl2__1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d3r7fc1_d3kzoa1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; N-acetylornithine carbamoyltransferase activity [GO:0043857]; ornithine carbamoyltransferase activity [GO:0004585]
d3r7kb2_d5lnxh2__1			Actinobacteria	Firmicutes	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	plasma membrane [GO:0005886]; acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor [GO:0052890]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]		plasma membrane [GO:0005886]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor [GO:0052890]
d3r7kd2_d2r0na1__1		Metazoa	Actinobacteria	Chordata	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA dehydrogenase activity [GO:0004361]; glutaryl-CoA hydrolase activity [GO:0044466]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lysine catabolic process [GO:0006554]; tryptophan metabolic process [GO:0006568]		fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lysine catabolic process [GO:0006554]; tryptophan metabolic process [GO:0006568]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	acyl-CoA dehydrogenase activity [GO:0003995]; flavin adenine dinucleotide binding [GO:0050660]	fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA dehydrogenase activity [GO:0004361]; glutaryl-CoA hydrolase activity [GO:0044466]
d3r7la1_d2otcd2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]
d3r7ld2_d1js1y1__1			Firmicutes	Bacteroidetes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; carboxyl- or carbamoyltransferase activity [GO:0016743]
d3r7ld2_d3e2pd2__1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]
d3r7xb__d4yb7j1__1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	histidine biosynthetic process [GO:0000105]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]	cytoplasm [GO:0005737]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d3r87a__d2glvc___1			Proteobacteria	Proteobacteria	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		fatty acid biosynthetic process [GO:0006633]; lipid A biosynthetic process [GO:0009245]		cytoplasm [GO:0005737]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]
d3r87a__d2xflh___1			Proteobacteria	Actinobacteria	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]						hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	
d3r8bb__d7fabl1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	extracellular region [GO:0005576]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3r8bi2_d1fnwf2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d3r8bl__d1kprd1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3r8bl__d3mlwl1__1			Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d3r8bn__d2a6ja1__1			Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d3r8qa1_d3t04d1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]
d3r8qa2_d1pvha2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]; ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	ciliary neurotrophic factor-mediated signaling pathway [GO:0070120]; cytokine-mediated signaling pathway [GO:0019221]; glycogen metabolic process [GO:0005977]; interleukin-27-mediated signaling pathway [GO:0070106]; interleukin-35-mediated signaling pathway [GO:0070757]; interleukin-6-mediated signaling pathway [GO:0070102]; leukemia inhibitory factor signaling pathway [GO:0048861]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; oncostatin-M-mediated signaling pathway [GO:0038165]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of Notch signaling pathway [GO:0008593]; response to cytokine [GO:0034097]; viral process [GO:0016032]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	ciliary neurotrophic factor receptor complex [GO:0070110]; dendrite [GO:0030425]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; oncostatin-M receptor complex [GO:0005900]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]	ciliary neurotrophic factor receptor activity [GO:0004897]; ciliary neurotrophic factor receptor binding [GO:0005127]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; growth factor binding [GO:0019838]; identical protein binding [GO:0042802]; interleukin-11 binding [GO:0019970]; interleukin-11 receptor activity [GO:0004921]; interleukin-27 receptor activity [GO:0045509]; protein homodimerization activity [GO:0042803]
d3r8qa3_d5dfta___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]; acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; calcium-independent cell-matrix adhesion [GO:0007161]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; integrin activation [GO:0033622]; interaction with symbiont [GO:0051702]; leukocyte migration [GO:0050900]; negative regulation of transforming growth factor-beta secretion [GO:2001202]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; peptide cross-linking [GO:0018149]; platelet degranulation [GO:0002576]; positive regulation of axon extension [GO:0045773]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; post-translational protein modification [GO:0043687]; regulation of cell shape [GO:0008360]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of protein phosphorylation [GO:0001932]; response to wounding [GO:0009611]; substrate adhesion-dependent cell spreading [GO:0034446]; symbiotic process mediated by secreted substance [GO:0052047]; wound healing [GO:0042060]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; fibrinogen complex [GO:0005577]; platelet alpha granule lumen [GO:0031093]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; peptidase activator activity [GO:0016504]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; proteoglycan binding [GO:0043394]; signaling receptor binding [GO:0005102]
d3r8rb__d1f5zd___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	N-acetylneuraminate lyase activity [GO:0008747]
d3r8re__d1l6wj___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	fructose metabolic process [GO:0006000]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	fructose 6-phosphate aldolase activity [GO:0097023]
d3r8rm__d1zajc___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]	I band [GO:0031674]; M band [GO:0031430]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	fructose-bisphosphate aldolase activity [GO:0004332]
d3r8rm__d3js3b___1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	3-dehydroquinate dehydratase activity [GO:0003855]; 3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	3,4-dihydroxybenzoate biosynthetic process [GO:0046279]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]		aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	3-dehydroquinate dehydratase activity [GO:0003855]
d3r8ru__d1ok6g___1			Firmicutes	Crenarchaeota	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	fructose-bisphosphate aldolase activity [GO:0004332]
d3r8rw__d4s1fn1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	fructose metabolic process [GO:0006000]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	fructose 6-phosphate aldolase activity [GO:0097023]
d3r8rw__d4u4md___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; 2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]; aldonic acid catabolic process [GO:0046176]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	aldonic acid catabolic process [GO:0046176]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; identical protein binding [GO:0042802]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	2-dehydro-3-deoxy-D-gluconate aldolase activity [GO:0061677]; 2-dehydro-3-deoxy-D-pentonate aldolase activity [GO:0047440]; identical protein binding [GO:0042802]
d3r8wa__d4yb4a___1	Viridiplantae		Streptophyta	Deinococcus-Thermus	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; plastid [GO:0009536]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD+ binding [GO:0070403]; protein homodimerization activity [GO:0042803]; embryo sac development [GO:0009553]; leucine biosynthetic process [GO:0009098]; pollen development [GO:0009555]	homoisocitrate dehydrogenase activity [GO:0047046]; metal ion binding [GO:0046872]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	embryo sac development [GO:0009553]; leucine biosynthetic process [GO:0009098]; pollen development [GO:0009555]	lysine biosynthetic process via aminoadipic acid [GO:0019878]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; plastid [GO:0009536]		3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD+ binding [GO:0070403]; protein homodimerization activity [GO:0042803]	homoisocitrate dehydrogenase activity [GO:0047046]; metal ion binding [GO:0046872]
d3r95b__d1qsod___1		Fungi	Proteobacteria	Ascomycota	N-acetyltransferase activity [GO:0008080]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; histone acetyltransferase activity [GO:0004402]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]; protein acetylation [GO:0006473]		protein acetylation [GO:0006473]		cytoplasm [GO:0005737]	N-acetyltransferase activity [GO:0008080]; nucleotide binding [GO:0000166]	histone acetyltransferase activity [GO:0004402]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]
d3r96a__d1yx0a1__1			Proteobacteria	Firmicutes	N-acetyltransferase activity [GO:0008080]; nucleotide binding [GO:0000166]	N-acetyltransferase activity [GO:0008080]					N-acetyltransferase activity [GO:0008080]; nucleotide binding [GO:0000166]	N-acetyltransferase activity [GO:0008080]
d3r98a__d4m11a2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d3r9gb__d1m1dc___1		Fungi	Proteobacteria	Ascomycota	N-acetyltransferase activity [GO:0008080]; nucleotide binding [GO:0000166]	CENP-A containing nucleosome [GO:0043505]; nuclear nucleosome [GO:0000788]; nucleus [GO:0005634]; replication fork protection complex [GO:0031298]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]; chromatin assembly or disassembly [GO:0006333]; global genome nucleotide-excision repair [GO:0070911]; rRNA transcription [GO:0009303]; sexual sporulation resulting in formation of a cellular spore [GO:0043935]		chromatin assembly or disassembly [GO:0006333]; global genome nucleotide-excision repair [GO:0070911]; rRNA transcription [GO:0009303]; sexual sporulation resulting in formation of a cellular spore [GO:0043935]		CENP-A containing nucleosome [GO:0043505]; nuclear nucleosome [GO:0000788]; nucleus [GO:0005634]; replication fork protection complex [GO:0031298]	N-acetyltransferase activity [GO:0008080]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3r9pa1_d2bh1b1__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	Gram-negative-bacterium-type cell wall [GO:0009276]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type II protein secretion system complex [GO:0015627]; protein secretion [GO:0009306]; protein secretion by the type II secretion system [GO:0015628]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	protein secretion [GO:0009306]; protein secretion by the type II secretion system [GO:0015628]	cytoplasm [GO:0005737]	Gram-negative-bacterium-type cell wall [GO:0009276]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; type II protein secretion system complex [GO:0015627]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]	
d3r9qc__d1yg8j___1			Actinobacteria	Proteobacteria	isomerase activity [GO:0016853]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	isomerase activity [GO:0016853]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3r9ta__d1xnya1__1			Actinobacteria	Actinobacteria	catalytic activity [GO:0003824]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		acetyl-CoA carboxylase complex [GO:0009317]	catalytic activity [GO:0003824]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]
d3r9xb__d1i1na___1		Metazoa	Aquificae	Chordata	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ribosomal small subunit binding [GO:0043024]; rRNA binding [GO:0019843]; small ribosomal subunit rRNA binding [GO:0070181]; ribosomal small subunit assembly [GO:0000028]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; cadherin binding [GO:0045296]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]; protein methylation [GO:0006479]; protein repair [GO:0030091]	ribosomal small subunit assembly [GO:0000028]	protein methylation [GO:0006479]; protein repair [GO:0030091]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ribosomal small subunit binding [GO:0043024]; rRNA binding [GO:0019843]; small ribosomal subunit rRNA binding [GO:0070181]	cadherin binding [GO:0045296]; protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719]
d3ra2a__d1m06g___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]; DNA binding [GO:0003677]			viral capsid [GO:0019028]	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	DNA binding [GO:0003677]
d3ra7l1_d1i7zb1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ra7l2_d1clyh1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ra7m2_d6elll1__1												
d3rapr__d1ukya___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; midbody [GO:0030496]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; actin cytoskeleton reorganization [GO:0031532]; cellular protein localization [GO:0034613]; cellular response to drug [GO:0035690]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to plasma membrane [GO:0072659]; Rap protein signal transduction [GO:0032486]; regulation of dendrite morphogenesis [GO:0048814]; regulation of JNK cascade [GO:0046328]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; uridylate kinase activity [GO:0009041]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; nucleobase-containing compound metabolic process [GO:0006139]; pyrimidine nucleotide biosynthetic process [GO:0006221]	actin cytoskeleton reorganization [GO:0031532]; cellular protein localization [GO:0034613]; cellular response to drug [GO:0035690]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to plasma membrane [GO:0072659]; Rap protein signal transduction [GO:0032486]; regulation of dendrite morphogenesis [GO:0048814]; regulation of JNK cascade [GO:0046328]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; nucleobase-containing compound metabolic process [GO:0006139]; pyrimidine nucleotide biosynthetic process [GO:0006221]	cytosol [GO:0005829]; midbody [GO:0030496]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]	adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; uridylate kinase activity [GO:0009041]
d3rara__d5bwba___1	Fungi	Metazoa	Ascomycota	Chordata	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	lipid catabolic process [GO:0016042]	acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	triglyceride lipase activity [GO:0004806]	acetylcholinesterase activity [GO:0003990]
d3raua__d2ff4b2__1	Metazoa	Fungi	Chordata	Ascomycota	ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]; cellular response to cytokine stimulus [GO:0071345]; cilium assembly [GO:0060271]; early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; negative regulation of epithelial cell migration [GO:0010633]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of homophilic cell adhesion [GO:1903387]; positive regulation of Wnt protein secretion [GO:0061357]; protein transport [GO:0015031]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	chromatin [GO:0000785]; nucleus [GO:0005634]; double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; histone binding [GO:0042393]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; G1 DNA damage checkpoint [GO:0044783]; intra-S DNA damage checkpoint [GO:0031573]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of DNA replication [GO:0008156]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]	cellular response to cytokine stimulus [GO:0071345]; cilium assembly [GO:0060271]; early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; negative regulation of epithelial cell migration [GO:0010633]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of homophilic cell adhesion [GO:1903387]; positive regulation of Wnt protein secretion [GO:0061357]; protein transport [GO:0015031]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; G1 DNA damage checkpoint [GO:0044783]; intra-S DNA damage checkpoint [GO:0031573]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of DNA replication [GO:0008156]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]	ciliary basal body [GO:0036064]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin [GO:0000785]; nucleus [GO:0005634]	protein kinase binding [GO:0019901]; protein tyrosine phosphatase activity [GO:0004725]	double-stranded DNA binding [GO:0003690]; enzyme activator activity [GO:0008047]; histone binding [GO:0042393]
d3rbca__d2chpc___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3rbca__d3bvkf1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d3rbcc__d4lpma___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3rbcf__d1pj1b___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3rbcg__d5jklk___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3rbch__d1r65a___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3rbcl__d1afra___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]	chloroplast [GO:0009507]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d3rbcm__d3pwqa1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]	cytosol [GO:0005829]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	
d3rbcn__d2x17y___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3rbco__d3n37a___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3rbcq__d1h0na___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; deoxyribonucleotide metabolic process [GO:0009262]; DNA replication [GO:0006260]; protein heterotetramerization [GO:0051290]	cell [GO:0005623]	cytosol [GO:0005829]; nuclear envelope [GO:0005635]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3rbcr__d1sofe___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3rbcr__d5jklg___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3rbcs__d2inda___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d3rbct__d1pima___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3rbct__d3e1ja___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3rbcu__d4to9v___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3rbcv__d2yjjf___1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3rbob__d1nipa___1				Proteobacteria		molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]		nitrogen fixation [GO:0009399]		molybdenum-iron nitrogenase complex [GO:0016612]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d3rbxa1_d1ykfd2__1			Euryarchaeota	Firmicutes	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	potassium ion transport [GO:0006813]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]
d3rbxc1_d4ro0s1__1			Euryarchaeota	Euryarchaeota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3rbxe1_d2fy8b1__1			Euryarchaeota	Euryarchaeota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	potassium ion transport [GO:0006813]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3rcaa1_d1xlnb___1				Proteobacteria		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]						2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3rcaa2_d2w3sg2__1				Proteobacteria		molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]						molybdenum ion binding [GO:0030151]; oxidoreductase activity [GO:0016491]
d3rcab2_d1rm6e1__1				Proteobacteria		4 iron, 4 sulfur cluster binding [GO:0051539]; 4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]						4-hydroxybenzoyl-CoA reductase activity [GO:0018525]; 4 iron, 4 sulfur cluster binding [GO:0051539]; FAD binding [GO:0071949]; metal ion binding [GO:0046872]
d3rcaj1_d5h57e___1		Viridiplantae		Streptophyta		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; etioplast stroma [GO:0009578]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; electron transport chain [GO:0022900]		electron transport chain [GO:0022900]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; etioplast stroma [GO:0009578]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3rcak1_d2vfta1__1				Actinobacteria		membrane [GO:0016020]; D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]				membrane [GO:0016020]		D-arabinono-1,4-lactone oxidase activity [GO:0003885]; FAD binding [GO:0071949]; xylitol oxidase activity [GO:0050582]
d3rckx__d1iipa2__1	Metazoa	Metazoa	Chordata	Chordata	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cyclosporin A binding [GO:0016018]; estrogen receptor binding [GO:0030331]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; transcription factor binding [GO:0008134]; unfolded protein binding [GO:0051082]; apoptotic process [GO:0006915]; cellular response to UV-A [GO:0071492]; chaperone-mediated protein folding [GO:0061077]; lipid droplet organization [GO:0034389]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; protein transport [GO:0015031]; protein-containing complex assembly [GO:0065003]	apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	apoptotic process [GO:0006915]; cellular response to UV-A [GO:0071492]; chaperone-mediated protein folding [GO:0061077]; lipid droplet organization [GO:0034389]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein-containing complex assembly [GO:0065003]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; protein transport [GO:0015031]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]	cyclosporin A binding [GO:0016018]; estrogen receptor binding [GO:0030331]; Hsp70 protein binding [GO:0030544]; Hsp90 protein binding [GO:0051879]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; transcription factor binding [GO:0008134]; unfolded protein binding [GO:0051082]
d3rcwg__d5dbmb___1	Metazoa	Metazoa	Chordata	Chordata	dendrite [GO:0030425]; MOZ/MORF histone acetyltransferase complex [GO:0070776]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; perikaryon [GO:0043204]; histone binding [GO:0042393]; metal ion binding [GO:0046872]; histone H3 acetylation [GO:0043966]; response to electrical stimulus [GO:0051602]; response to immobilization stress [GO:0035902]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	histone H3 acetylation [GO:0043966]; response to electrical stimulus [GO:0051602]; response to immobilization stress [GO:0035902]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	dendrite [GO:0030425]; MOZ/MORF histone acetyltransferase complex [GO:0070776]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; perikaryon [GO:0043204]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	histone binding [GO:0042393]; metal ion binding [GO:0046872]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3rcwg__d5uvya1__1	Metazoa	Metazoa	Chordata	Chordata	dendrite [GO:0030425]; MOZ/MORF histone acetyltransferase complex [GO:0070776]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; perikaryon [GO:0043204]; histone binding [GO:0042393]; metal ion binding [GO:0046872]; histone H3 acetylation [GO:0043966]; response to electrical stimulus [GO:0051602]; response to immobilization stress [GO:0035902]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	histone H3 acetylation [GO:0043966]; response to electrical stimulus [GO:0051602]; response to immobilization stress [GO:0035902]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	dendrite [GO:0030425]; MOZ/MORF histone acetyltransferase complex [GO:0070776]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; perikaryon [GO:0043204]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	histone binding [GO:0042393]; metal ion binding [GO:0046872]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]
d3rd2a1_d5mn9a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; cytokine production [GO:0001816]; positive regulation of transcription by RNA polymerase II [GO:0045944]	cytoplasm [GO:0005737]; cytosolic small ribosomal subunit [GO:0022627]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]; translation [GO:0006412]	cytokine production [GO:0001816]; positive regulation of transcription by RNA polymerase II [GO:0045944]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]; translation [GO:0006412]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosolic small ribosomal subunit [GO:0022627]; nucleus [GO:0005634]		metal ion binding [GO:0046872]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d3rdax__d4frua1__1	Metazoa	Metazoa	Chordata	Chordata	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	protein-containing complex [GO:0032991]; cyclosporin A binding [GO:0016018]; metal ion binding [GO:0046872]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]	apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]	protein-containing complex [GO:0032991]	cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]	cyclosporin A binding [GO:0016018]; metal ion binding [GO:0046872]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]
d3rdba__d1c5fg___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]; cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]; apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein folding [GO:0006457]	apoptotic mitochondrial changes [GO:0008637]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; mitochondrial outer membrane permeabilization involved in programmed cell death [GO:1902686]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of oxidative phosphorylation uncoupler activity [GO:2000276]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of necrotic cell death [GO:0010939]; regulation of proton-transporting ATPase activity, rotational mechanism [GO:0010849]; response to ischemia [GO:0002931]	protein folding [GO:0006457]	membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial permeability transition pore complex [GO:0005757]; mitochondrion [GO:0005739]		cyclosporin A binding [GO:0016018]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; unfolded protein binding [GO:0051082]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d3rdib1_d3e5ua2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]
d3rdkb1_d1xyzb___1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan endo-1,3-beta-xylosidase activity [GO:0033905]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	cell wall [GO:0005618]; extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan endo-1,3-beta-xylosidase activity [GO:0033905]
d3rdma1_d1swcb___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3rdoa1_d3szih___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3rdqa1_d4cphb___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3rdsa1_d4bj8h___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3rdua1_d4z28a___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]
d3rdwa__d4xs4e___1			Proteobacteria	Proteobacteria	arsenate reductase (glutaredoxin) activity [GO:0008794]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]		cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cytosol [GO:0005829]	arsenate reductase (glutaredoxin) activity [GO:0008794]	thioredoxin peroxidase activity [GO:0008379]
d3rdwb__d4xrdb___1			Proteobacteria	Proteobacteria	arsenate reductase (glutaredoxin) activity [GO:0008794]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]		cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cytosol [GO:0005829]	arsenate reductase (glutaredoxin) activity [GO:0008794]	thioredoxin peroxidase activity [GO:0008379]
d3rdxb1_d2of9a1__1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3re5a1_d3szid1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3re7c__d5jkla___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3re7d__d1bcff___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3re7f__d3vpnb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cell [GO:0005623]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3re7g__d1xvec___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3re7i__d4rc8b___1	Metazoa		Chordata	Cyanobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	aldehyde decarbonylase activity [GO:0071771]; aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	aldehyde decarbonylase activity [GO:0071771]; aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]
d3re7j__d5l8bv___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]
d3re7m__d4dr0a___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3re7o__d3e1ql___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3re7v__d2fjce___1	Metazoa		Chordata	Spirochaetes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3re7w__d3vnxa___1	Metazoa	Viridiplantae	Chordata	Chlorophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3re7x__d2bkcm___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3rema__d4oj7a___1			Proteobacteria		carbon-oxygen lyase activity [GO:0016835]; chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]; chorismate metabolic process [GO:0046417]; pyochelin biosynthetic process [GO:0042864]; salicylic acid biosynthetic process [GO:0009697]		chorismate metabolic process [GO:0046417]; pyochelin biosynthetic process [GO:0042864]; salicylic acid biosynthetic process [GO:0009697]				carbon-oxygen lyase activity [GO:0016835]; chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]	
d3remb__d2fp2b___1			Proteobacteria	Actinobacteria	carbon-oxygen lyase activity [GO:0016835]; chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]; chorismate metabolic process [GO:0046417]; pyochelin biosynthetic process [GO:0042864]; salicylic acid biosynthetic process [GO:0009697]	extracellular region [GO:0005576]; chorismate mutase activity [GO:0004106]; chorismate metabolic process [GO:0046417]	chorismate metabolic process [GO:0046417]; pyochelin biosynthetic process [GO:0042864]; salicylic acid biosynthetic process [GO:0009697]	chorismate metabolic process [GO:0046417]		extracellular region [GO:0005576]	carbon-oxygen lyase activity [GO:0016835]; chorismate mutase activity [GO:0004106]; isochorismate pyruvate lyase activity [GO:0043904]	chorismate mutase activity [GO:0004106]
d3reoa1_d3mwma___1	Viridiplantae		Streptophyta	Actinobacteria	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of secondary metabolite biosynthetic process [GO:1900376]		negative regulation of transcription, DNA-templated [GO:0045892]; regulation of secondary metabolite biosynthetic process [GO:1900376]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription repressor activity [GO:0001217]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; zinc ion binding [GO:0008270]
d3reob1_d5nl9a1__1	Viridiplantae		Streptophyta	Spirochaetes	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]					(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3reob2_d5cvud2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]					(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]
d3rerc__d4j5yb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; bent DNA binding [GO:0003681]; RNA binding [GO:0003723]; negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	negative regulation of translation, ncRNA-mediated [GO:0040033]; positive regulation of translation, ncRNA-mediated [GO:0045975]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytosol [GO:0005829]	cytosol [GO:0005829]	bent DNA binding [GO:0003681]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3reva1_d2gtza1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3revb1_d3nz8b1__1												
d3revb1_d4whtn2__1						viral envelope [GO:0019031]				viral envelope [GO:0019031]		
d3rewe__d1wt5b___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3rexa__d2e41b2__1			Euryarchaeota	Euryarchaeota	aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; tRNA aminoacylation for protein translation [GO:0006418]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]; cellular protein modification process [GO:0006464]	tRNA aminoacylation for protein translation [GO:0006418]	cellular protein modification process [GO:0006464]			aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]	ATP binding [GO:0005524]; biotin-[acetyl-CoA-carboxylase] ligase activity [GO:0004077]
d3rf4b__d5b4oa___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d3rf5a__d4lhpd___1	Metazoa		Nematoda (roundworms)	Actinobacteria	cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]						cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]	
d3rf5a__d5bs9a___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d3rf5b__d3djie___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d3rfbb__d4cqha2__1			Firmicutes	Deinococcus-Thermus	cytosol [GO:0005829]; methionine-R-sulfoxide reductase activity [GO:0070191]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]		methionine-R-sulfoxide reductase activity [GO:0070191]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3rffa__d5h7xc___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d3rfna__d1nyra3__1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; aminoacyl-tRNA editing activity [GO:0002161]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]; threonyl-tRNA aminoacylation [GO:0006435]		threonyl-tRNA aminoacylation [GO:0006435]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aminoacyl-tRNA editing activity [GO:0002161]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; threonine-tRNA ligase activity [GO:0004829]; tRNA binding [GO:0000049]
d3rfza2_d1qunp2__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]	mannose binding [GO:0005537]	mannose binding [GO:0005537]
d3rfzd1_d4z3ja___1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3rg8a__d2fw8b___1			Spirochaetes	Proteobacteria	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d3rg8a__d3orsg1__1			Spirochaetes	Firmicutes	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d3rg8d__d4b4ka___1			Spirochaetes	Firmicutes	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]
d3rg8e__d4ycdb___1			Spirochaetes	Proteobacteria	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d3rg8f__d1xmpc1__1			Spirochaetes	Firmicutes	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]
d3rgaa2_d5tuxa2__1			Actinobacteria	Cyanobacteria	isomerase activity [GO:0016853]; antibiotic biosynthetic process [GO:0017000]	phycobilisome [GO:0030089]; chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]; light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	antibiotic biosynthetic process [GO:0017000]	light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	isomerase activity [GO:0016853]	chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]
d3rgda__d2yjjj___1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3rgde__d2x178___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3rgdf__d5jklj___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3rgdi__d3vpob1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cell [GO:0005623]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3rgdn__d2j2ff___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]	chloroplast [GO:0009507]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d3rgdo__d1bfrl___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3rgdu__d4rc7b___1	Metazoa		Chordata	Cyanobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	aldehyde decarbonylase activity [GO:0071771]; aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	aldehyde decarbonylase activity [GO:0071771]; aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]
d3rgdv__d4cvta1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3rgga__d4b4kg___1			Spirochaetes	Firmicutes	5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-amino-4-imidazole carboxylate lyase activity [GO:0043727]; phosphoribosylaminoimidazole carboxylase activity [GO:0004638]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]
d3rgra__d4xdwe___1			Proteobacteria	Actinobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	limonene-1,2-epoxide hydrolase activity [GO:0018744]	steroid metabolic process [GO:0008202]				steroid delta-isomerase activity [GO:0004769]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d3rgtd1_d4ihce1__1			Proteobacteria	Proteobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d3rgva1_d1ai1l1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3rgva1_d3okoa1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d3rgvb1_d1fl5b2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	
d3rgvd1_d4en3a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3rh1a__d2vq9a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; ribonuclease activity [GO:0004540]; RNA binding [GO:0003723]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; immune system process [GO:0002376]		angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; immune system process [GO:0002376]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; ribonuclease activity [GO:0004540]; RNA binding [GO:0003723]
d3rh4a1_d3uxob1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d3rhba__d3fhsa3__1	Viridiplantae		Streptophyta		cell [GO:0005623]; chloroplast [GO:0009507]; electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; iron-sulfur cluster assembly [GO:0016226]		cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; iron-sulfur cluster assembly [GO:0016226]		cell [GO:0005623]; chloroplast [GO:0009507]		electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]	
d3rhca__d1yexe___1	Viridiplantae		Streptophyta	Proteobacteria	cell [GO:0005623]; chloroplast [GO:0009507]; electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; iron-sulfur cluster assembly [GO:0016226]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; iron-sulfur cluster assembly [GO:0016226]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; chloroplast [GO:0009507]	cell [GO:0005623]; cytosol [GO:0005829]	electron transfer activity [GO:0009055]; glutathione-disulfide reductase activity [GO:0004362]; protein disulfide oxidoreductase activity [GO:0015035]	thioredoxin peroxidase activity [GO:0008379]
d3rhhb1_d5kllc___1			Firmicutes	Proteobacteria	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]					glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3rhhc__d3n83h___1		Metazoa	Firmicutes	Chordata	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; nucleotide binding [GO:0000166]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity [GO:0008886]; nucleotide binding [GO:0000166]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3rhoa__d1nzxh___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3rhob__d4i9bb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3rhoc__d2onog___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3rhoc__d4zukh___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]; cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]
d3rhod__d3inlc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3rhod__d4qn2c___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; glycine betaine biosynthetic process from choline [GO:0019285]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine betaine biosynthetic process from choline [GO:0019285]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d3rhpc__d5exfa___1	Metazoa		Chordata	Crenarchaeota	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]; protein-containing complex [GO:0032991]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3rhqa__d1wnda___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; 1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; putrescine catabolic process [GO:0009447]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	putrescine catabolic process [GO:0009447]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	1-pyrroline dehydrogenase activity [GO:0033737]; aminobutyraldehyde dehydrogenase activity [GO:0019145]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]
d3rhqc__d1nzze___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3ri3a__d1b3rb1__1		Metazoa	Actinobacteria	Chordata	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]	antibiotic biosynthetic process [GO:0017000]	chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	oxidoreductase activity [GO:0016491]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]
d3ri4a__d1i5zb1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3ri7a__d1pizb___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	toluene catabolic process [GO:0042203]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3ri8a__d3aktb___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d3ri9a__d1xyoa1__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d3ri9a__d2auyb___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]		endo-1,4-beta-xylanase activity [GO:0031176]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3rica__d4gxgb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; ceramide 1-phosphate binding [GO:1902387]; ceramide 1-phosphate transfer activity [GO:1902388]; glycolipid binding [GO:0051861]; glycolipid transfer activity [GO:0017089]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; lipid transfer activity [GO:0120013]; ceramide transport [GO:0035627]; glycosphingolipid metabolic process [GO:0006687]; intermembrane lipid transfer [GO:0120009]	cytosol [GO:0005829]; ceramide 1-phosphate binding [GO:1902387]; ceramide 1-phosphate transfer activity [GO:1902388]; glycolipid binding [GO:0051861]; glycolipid transfer activity [GO:0017089]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; lipid transfer activity [GO:0120013]; ceramide transport [GO:0035627]; glycosphingolipid metabolic process [GO:0006687]; intermembrane lipid transfer [GO:0120009]	ceramide transport [GO:0035627]; glycosphingolipid metabolic process [GO:0006687]; intermembrane lipid transfer [GO:0120009]	ceramide transport [GO:0035627]; glycosphingolipid metabolic process [GO:0006687]; intermembrane lipid transfer [GO:0120009]	cytosol [GO:0005829]	cytosol [GO:0005829]	ceramide 1-phosphate binding [GO:1902387]; ceramide 1-phosphate transfer activity [GO:1902388]; glycolipid binding [GO:0051861]; glycolipid transfer activity [GO:0017089]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; lipid transfer activity [GO:0120013]	ceramide 1-phosphate binding [GO:1902387]; ceramide 1-phosphate transfer activity [GO:1902388]; glycolipid binding [GO:0051861]; glycolipid transfer activity [GO:0017089]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; lipid transfer activity [GO:0120013]
d3ridc__d1rhaa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d3rieb__d4gf5k___1			Apicomplexa	Actinobacteria	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	O-methyltransferase activity [GO:0008171]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]		cytosol [GO:0005829]		spermidine synthase activity [GO:0004766]	O-methyltransferase activity [GO:0008171]
d3riha__d2p9cb1__1			Actinobacteria	Proteobacteria		cytosol [GO:0005829]; 2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]; L-serine biosynthetic process [GO:0006564]		L-serine biosynthetic process [GO:0006564]		cytosol [GO:0005829]		2-hydroxyglutarate dehydrogenase activity [GO:0047545]; glyoxylate reductase (NADP) activity [GO:0030267]; hydroxypyruvate reductase activity [GO:0016618]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; phosphoglycerate dehydrogenase activity [GO:0004617]; serine binding [GO:0070905]
d3rihd__d4ijwe___1		Metazoa	Actinobacteria	Chordata		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d3rika2_d3baja2__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3rika2_d3i3bb3__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	beta-galactosidase complex [GO:0009341]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3rikb2_d1b2ya2__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3rikb2_d1px8a2__1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	xylan catabolic process [GO:0045493]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d3rikc2_d1wcgb___1	Metazoa	Metazoa	Chordata	Arthropoda	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]; carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	glucosinolate glucohydrolase activity [GO:0102799]; metal ion binding [GO:0046872]; thioglucosidase activity [GO:0019137]
d3rikd2_d1zjba1__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3rilb2_d2bv9a1__1	Metazoa		Chordata	Firmicutes	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	cellulose catabolic process [GO:0030245]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]		glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]	cellulase activity [GO:0008810]
d3riqa__d2z8ga2__1		Fungi		Ascomycota		extracellular region [GO:0005576]; isopullulanase activity [GO:0051675]; metabolic process [GO:0008152]		metabolic process [GO:0008152]		extracellular region [GO:0005576]		isopullulanase activity [GO:0051675]
d3rita2_d1pdza1__1		Metazoa	Proteobacteria	Arthropoda	chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]	phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]	glycolytic process [GO:0006096]		phosphopyruvate hydratase complex [GO:0000015]	chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3ritc1_d2p88f1__1			Proteobacteria	Firmicutes	chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]; peptide metabolic process [GO:0006518]	catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]	peptide metabolic process [GO:0006518]			chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity [GO:0016854]
d3rj3a__d1o6hb2__1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; regulation of complement activation [GO:0030449]; regulation of complement-dependent cytotoxicity [GO:1903659]; viral process [GO:0016032]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; regulation of complement activation [GO:0030449]; regulation of complement-dependent cytotoxicity [GO:1903659]; viral process [GO:0016032]	hopanoid biosynthetic process [GO:0019746]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]
d3rj3b__d1o1rb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; regulation of complement activation [GO:0030449]; regulation of complement-dependent cytotoxicity [GO:1903659]; viral process [GO:0016032]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; regulation of complement activation [GO:0030449]; regulation of complement-dependent cytotoxicity [GO:1903659]; viral process [GO:0016032]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d3rj3c__d1tnud___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; regulation of complement activation [GO:0030449]; regulation of complement-dependent cytotoxicity [GO:1903659]; viral process [GO:0016032]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; regulation of complement activation [GO:0030449]; regulation of complement-dependent cytotoxicity [GO:1903659]; viral process [GO:0016032]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d3rj6b__d1jy7a___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3rj6b__d4f68a___1	Metazoa	Metazoa	Chordata	Nemertea (ribbon worms)	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3rjha3_d4k4hi3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d3rjha3_d4k8va1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immune response [GO:0050776]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]; regulation of type I interferon production [GO:0032479]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	activation of innate immune response [GO:0002218]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; paracrine signaling [GO:0038001]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cGMP-mediated signaling [GO:0010753]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]; regulation of immune response [GO:0050776]; regulation of immunoglobulin production [GO:0002637]; regulation of T cell activation [GO:0050863]; regulation of type I interferon production [GO:0032479]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; site of double-strand break [GO:0035861]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclic-GMP-AMP synthase activity [GO:0061501]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]
d3rjja1_d4i2ea1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3rjka3_d1no5b___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleotidyltransferase activity [GO:0016779]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]		cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]		damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	nucleotidyltransferase activity [GO:0016779]
d3rjld__d3n82h___1		Metazoa	Firmicutes	Chordata	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3rjlf__d1nzxb___1		Metazoa	Firmicutes	Chordata	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3rjlh__d2onof___1		Metazoa	Firmicutes	Chordata	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]; glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3rjnb__d1mbia___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]					heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3rjqb__d4a6yl2__1												
d3rjxa__d2gk1.9__1		Metazoa	Thermotogae	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	carbohydrate metabolic process [GO:0005975]	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neutrophil degranulation [GO:0043312]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]		acrosomal vesicle [GO:0001669]; azurophil granule [GO:0042582]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	acetylglucosaminyltransferase activity [GO:0008375]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d3rk8b__d1vpxe1__1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]
d3rkdc1_d5eiqa2__1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell Golgi apparatus [GO:0044177]; host cell surface [GO:0044228]; T=1 icosahedral viral capsid [GO:0039615]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; collagen receptor activity [GO:0038064]; neutrophil degranulation [GO:0043312]; osteoclast differentiation [GO:0030316]; regulation of immune response [GO:0050776]	entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	neutrophil degranulation [GO:0043312]; osteoclast differentiation [GO:0030316]; regulation of immune response [GO:0050776]	extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell Golgi apparatus [GO:0044177]; host cell surface [GO:0044228]; T=1 icosahedral viral capsid [GO:0039615]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	collagen receptor activity [GO:0038064]
d3rkdc2_d4xbpb2__1					extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell Golgi apparatus [GO:0044177]; host cell surface [GO:0044228]; T=1 icosahedral viral capsid [GO:0039615]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]		entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]		extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell Golgi apparatus [GO:0044177]; host cell surface [GO:0044228]; T=1 icosahedral viral capsid [GO:0039615]		identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	
d3rkdl1_d3v4pn2__1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell Golgi apparatus [GO:0044177]; host cell surface [GO:0044228]; T=1 icosahedral viral capsid [GO:0039615]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]	entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; cell migration [GO:0016477]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]	extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell Golgi apparatus [GO:0044177]; host cell surface [GO:0044228]; T=1 icosahedral viral capsid [GO:0039615]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]
d3rkdl1_d5k9kl2__1				Negarnaviricota	extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell Golgi apparatus [GO:0044177]; host cell surface [GO:0044228]; T=1 icosahedral viral capsid [GO:0039615]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell Golgi apparatus [GO:0044177]; host cell surface [GO:0044228]; T=1 icosahedral viral capsid [GO:0039615]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	host cell surface receptor binding [GO:0046789]
d3rkdl2_d1ifhh1__1					extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell Golgi apparatus [GO:0044177]; host cell surface [GO:0044228]; T=1 icosahedral viral capsid [GO:0039615]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]; entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]		entry receptor-mediated virion attachment to host cell [GO:0098670]; viral entry into host cell [GO:0046718]		extracellular region [GO:0005576]; host cell endoplasmic reticulum [GO:0044165]; host cell Golgi apparatus [GO:0044177]; host cell surface [GO:0044228]; T=1 icosahedral viral capsid [GO:0039615]		identical protein binding [GO:0042802]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	
d3rkjb__d1ycga2__1			Proteobacteria	Firmicutes	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d3rkka__d3a4ya___1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	rRNA processing [GO:0006364]	periplasmic space [GO:0042597]	cytoplasm [GO:0005737]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3rkkb__d4uama___1			Proteobacteria		periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	
d3rkpa1_d3rkpa3__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]			cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]	cell wall [GO:0005618]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3rksb__d5lula1__1	Viridiplantae		Streptophyta	Actinobacteria	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]						aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	
d3rksc__d4gi1a___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]			aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	triglyceride lipase activity [GO:0004806]
d3rl7a__d2yt7a1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]; cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; chemical synaptic transmission [GO:0007268]; in utero embryonic development [GO:0001701]; negative regulation of catalytic activity [GO:0043086]; protein transport [GO:0015031]; regulation of gene expression [GO:0010468]	actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	chemical synaptic transmission [GO:0007268]; in utero embryonic development [GO:0001701]; negative regulation of catalytic activity [GO:0043086]; protein transport [GO:0015031]; regulation of gene expression [GO:0010468]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]	cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]	amyloid-beta binding [GO:0001540]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]
d3rl7d1_d2jina___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]; cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; integral component of mitochondrial outer membrane [GO:0031307]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic density membrane [GO:0098839]; protein C-terminus binding [GO:0008022]; cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sprouting angiogenesis [GO:1903671]; protein targeting [GO:0006605]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of endocytosis [GO:0030100]; regulation of Notch signaling pathway [GO:0008593]; Rho protein signal transduction [GO:0007266]	actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sprouting angiogenesis [GO:1903671]; protein targeting [GO:0006605]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of endocytosis [GO:0030100]; regulation of Notch signaling pathway [GO:0008593]; Rho protein signal transduction [GO:0007266]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]	basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; integral component of mitochondrial outer membrane [GO:0031307]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic density membrane [GO:0098839]	cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]	protein C-terminus binding [GO:0008022]
d3rl7d1_d3lnxb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]; cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]; cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	cellular response to cytokine stimulus [GO:0071345]; negative regulation of protein phosphorylation [GO:0001933]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol biosynthetic process [GO:0006661]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]	cell body [GO:0044297]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; fibrillar center [GO:0001650]; lamellipodium [GO:0030027]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]	phosphatidylinositol 3-kinase regulatory subunit binding [GO:0036312]; protein tyrosine phosphatase activity [GO:0004725]
d3rl8e__d2zlel1__1	Metazoa		Chordata	Proteobacteria	adherens junction [GO:0005912]; beta-catenin destruction complex [GO:0030877]; bicellular tight junction [GO:0005923]; catenin complex [GO:0016342]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; Wnt signalosome [GO:1990909]; beta-catenin binding [GO:0008013]; dynein complex binding [GO:0070840]; gamma-catenin binding [GO:0045295]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin protein ligase binding [GO:0031625]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; insulin receptor signaling pathway [GO:0008286]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of microtubule depolymerization [GO:0007026]; pattern specification process [GO:0007389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration [GO:0030335]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of pseudopodium assembly [GO:0031274]; protein deubiquitination [GO:0016579]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell differentiation [GO:0045595]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; insulin receptor signaling pathway [GO:0008286]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of microtubule depolymerization [GO:0007026]; pattern specification process [GO:0007389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration [GO:0030335]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of pseudopodium assembly [GO:0031274]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homooligomerization [GO:0051260]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell differentiation [GO:0045595]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	adherens junction [GO:0005912]; beta-catenin destruction complex [GO:0030877]; bicellular tight junction [GO:0005923]; catenin complex [GO:0016342]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; lamellipodium [GO:0030027]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; Wnt signalosome [GO:1990909]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	beta-catenin binding [GO:0008013]; dynein complex binding [GO:0070840]; gamma-catenin binding [GO:0045295]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3rlaa__d1wvaa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d3rlda__d4cnwb___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3rlfb1_d1g5pa___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	molybdenum-iron nitrogenase complex [GO:0016612]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	nitrogen fixation [GO:0009399]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	molybdenum-iron nitrogenase complex [GO:0016612]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d3rloa1_d4jbma2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]
d3rloa2_d3rlna2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3rloa2_d4l5qa2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; double-stranded DNA binding [GO:0003690]; activation of innate immune response [GO:0002218]; cellular response to interferon-beta [GO:0035458]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of innate immune response [GO:0045824]; positive regulation of interleukin-1 beta production [GO:0032731]; response to bacterium [GO:0009617]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of innate immune response [GO:0002218]; cellular response to interferon-beta [GO:0035458]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of innate immune response [GO:0045824]; positive regulation of interleukin-1 beta production [GO:0032731]; response to bacterium [GO:0009617]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	double-stranded DNA binding [GO:0003690]
d3rlta1_d3o9ma___1		Metazoa		Chordata		blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]		choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]		blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]		acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]
d3rmca1_d2hbka2__1		Fungi		Ascomycota	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleus [GO:0005634]; 3'-5'-exoribonuclease activity [GO:0000175]; nucleotide binding [GO:0000166]; single-stranded RNA binding [GO:0003727]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; histone mRNA catabolic process [GO:0071044]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent antisense transcript catabolic process [GO:0071040]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent snoRNA catabolic process [GO:0071036]; nuclear polyadenylation-dependent snRNA catabolic process [GO:0071037]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; histone mRNA catabolic process [GO:0071044]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent antisense transcript catabolic process [GO:0071040]; nuclear polyadenylation-dependent CUT catabolic process [GO:0071039]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent snoRNA catabolic process [GO:0071036]; nuclear polyadenylation-dependent snRNA catabolic process [GO:0071037]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA at the site of transcription [GO:0071033]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]		nuclear exosome (RNase complex) [GO:0000176]; nucleolus [GO:0005730]; nucleus [GO:0005634]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3'-5'-exoribonuclease activity [GO:0000175]; nucleotide binding [GO:0000166]; single-stranded RNA binding [GO:0003727]
d3rmcc1_d3rr7a1__1				Deinococcus-Thermus	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]
d3rmkc__d3rn9c___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d3rmkd__d3isej___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	toluene catabolic process [GO:0042203]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3rmkf__d2rdbc___1			Proteobacteria	Proteobacteria	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; cellular aromatic compound metabolic process [GO:0006725]	toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]			oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d3rmua1_d1hana1__1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; metal ion binding [GO:0046872]; methylmalonyl-CoA epimerase activity [GO:0004493]; L-methylmalonyl-CoA metabolic process [GO:0046491]; short-chain fatty acid catabolic process [GO:0019626]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]; aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	L-methylmalonyl-CoA metabolic process [GO:0046491]; short-chain fatty acid catabolic process [GO:0019626]	aromatic compound catabolic process [GO:0019439]; xenobiotic catabolic process [GO:0042178]	mitochondrial matrix [GO:0005759]		metal ion binding [GO:0046872]; methylmalonyl-CoA epimerase activity [GO:0004493]	biphenyl-2,3-diol 1,2-dioxygenase activity [GO:0018583]; ferrous iron binding [GO:0008198]
d3rmub1_d1q0ca2__1	Metazoa		Chordata	Actinobacteria	mitochondrial matrix [GO:0005759]; metal ion binding [GO:0046872]; methylmalonyl-CoA epimerase activity [GO:0004493]; L-methylmalonyl-CoA metabolic process [GO:0046491]; short-chain fatty acid catabolic process [GO:0019626]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	L-methylmalonyl-CoA metabolic process [GO:0046491]; short-chain fatty acid catabolic process [GO:0019626]		mitochondrial matrix [GO:0005759]		metal ion binding [GO:0046872]; methylmalonyl-CoA epimerase activity [GO:0004493]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3rmzd__d1mafh___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]; methylamine metabolic process [GO:0030416]		methylamine metabolic process [GO:0030416]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	amine dehydrogenase activity [GO:0030058]; methylamine dehydrogenase (amicyanin) activity [GO:0052876]
d3rn2a2_d3b6yb1__1	Metazoa	Metazoa	Chordata	Chordata	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3rn2b2_d4qgua2__1	Metazoa	Metazoa	Chordata	Chordata	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3rn4a2_d1gn4a2__1	Fungi		Ascomycota	Actinobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; age-dependent response to oxidative stress involved in chronological cell aging [GO:0001324]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; reactive oxygen species metabolic process [GO:0072593]; replicative cell aging [GO:0001302]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	age-dependent response to oxidative stress involved in chronological cell aging [GO:0001324]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; reactive oxygen species metabolic process [GO:0072593]; replicative cell aging [GO:0001302]	evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; pathogenesis [GO:0009405]; response to oxidative stress [GO:0006979]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular region [GO:0005576]; periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3rn5a1_d3rnud1__1	Metazoa	Metazoa	Chordata	Chordata	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3rn5a2_d3rn5a1__1	Metazoa	Metazoa	Chordata	Chordata	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]
d3rn5b2_d3rnub1__1	Metazoa	Metazoa	Chordata	Chordata	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3rn5c1_d3rlna1__1	Metazoa	Metazoa	Chordata	Chordata	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3rn5c2_d3rnud2__1	Metazoa	Metazoa	Chordata	Chordata	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3rn5d2_d3rlna2__1	Metazoa	Metazoa	Chordata	Chordata	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3rn8b__d1fcka2__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d3rn8c__d3o2aa1__1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3rnaa__d1fz3d___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular aromatic compound metabolic process [GO:0006725]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]			metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3rnbb__d1f33c___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]		cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3rnbc__d3ge3c___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]	toluene catabolic process [GO:0042203]			metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d3rnca__d2j2ff___1		Viridiplantae	Proteobacteria	Streptophyta	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular aromatic compound metabolic process [GO:0006725]	fatty acid biosynthetic process [GO:0006633]		chloroplast [GO:0009507]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d3rnea__d2alxa___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular aromatic compound metabolic process [GO:0006725]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3rnfa__d1umnh___1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d3rnfa__d3n37a___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular aromatic compound metabolic process [GO:0006725]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]		cytoplasm [GO:0005737]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3rnfc__d4p1bf___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]	toluene catabolic process [GO:0042203]			metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d3rnga__d1pfrb___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	cellular aromatic compound metabolic process [GO:0006725]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3rngc__d3q3nc___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; toluene catabolic process [GO:0042203]	cellular aromatic compound metabolic process [GO:0006725]	toluene catabolic process [GO:0042203]			metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d3rnka__d4hx1a2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3rnna__d5nf6a___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; regulation of NMDA receptor activity [GO:2000310]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; excitatory synapse [GO:0060076]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic endocytic zone [GO:0098843]; postsynaptic membrane [GO:0045211]	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3rnqa__d4oclc___1	Metazoa	Fungi	Chordata	Ascomycota	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	proteasome complex [GO:0000502]; proteasome regulatory particle, lid subcomplex [GO:0008541]; proteasome storage granule [GO:0034515]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; ubiquitin-dependent protein catabolic process [GO:0006511]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; ubiquitin-dependent protein catabolic process [GO:0006511]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	proteasome complex [GO:0000502]; proteasome regulatory particle, lid subcomplex [GO:0008541]; proteasome storage granule [GO:0034515]		
d3rnua1_d3rlna1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3rnua1_d3rn2a1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]
d3rnuc1_d3rn5b1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of innate immune response [GO:0002218]; apoptotic process [GO:0006915]; cellular response to drug [GO:0035690]; cellular response to interferon-beta [GO:0035458]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein oligomerization [GO:0032461]; pyroptosis [GO:0070269]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	AIM2 inflammasome complex [GO:0097169]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]
d3rnud2_d3b6yb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of innate immune response [GO:0002218]; autophagy [GO:0006914]; cell population proliferation [GO:0008283]; cellular response to glucose starvation [GO:0042149]; cellular response to interferon-beta [GO:0035458]; cellular response to ionizing radiation [GO:0071479]; defense response to virus [GO:0051607]; hemopoiesis [GO:0030097]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of DNA binding [GO:0043392]; negative regulation of innate immune response [GO:0045824]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; positive regulation of cytokine production [GO:0001819]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of autophagy [GO:0010506]; regulation of gene expression, epigenetic [GO:0040029]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3rnzb__d1x10b___1			Firmicutes	Euryarchaeota	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cytosol [GO:0005829]; cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]			cytosol [GO:0005829]	cytosol [GO:0005829]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]	cysteine-type peptidase activity [GO:0008234]; pyroglutamyl-peptidase activity [GO:0016920]
d3ro6b2_d4enla1__1		Fungi	Proteobacteria	Ascomycota	chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3ro6c2_d3uxlc2__1			Proteobacteria	Proteobacteria	chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]			chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d3ro6e2_d3q45a2__1			Proteobacteria	Bacteroidetes	chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]	peptide metabolic process [GO:0006518]			chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d3ro6f2_d2baha2__1			Proteobacteria		chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]		catechol-containing compound catabolic process [GO:0019614]; cellular amino acid catabolic process [GO:0009063]; peptide metabolic process [GO:0006518]				chloromuconate cycloisomerase activity [GO:0018850]; magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]	
d3ro8b1_d3vd4b3__1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	cell wall [GO:0005618]; extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3ro8f1_d1xske4__1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	cell wall [GO:0005618]; extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d3ro8g1_d3i3bd3__1			Firmicutes	Proteobacteria	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	cell wall [GO:0005618]; extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3ro8h1_d1e56a___1		Viridiplantae	Firmicutes	Streptophyta	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	chloroplast [GO:0009507]; beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]; carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; cytokinin-activated signaling pathway [GO:0009736]	cell wall [GO:0005618]; extracellular region [GO:0005576]	chloroplast [GO:0009507]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	beta-glucosidase activity [GO:0008422]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; DIMBOA glucoside beta-D-glucosidase activity [GO:0102726]; fucosidase activity [GO:0015928]; galactosidase activity [GO:0015925]; mannosidase activity [GO:0015923]; scopolin beta-glucosidase activity [GO:0102483]; xylanase activity [GO:0097599]
d3ro9b1_d3d84x___1	Fungi	Metazoa	Ascomycota	Chordata	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3roaa1_d3q1ha1__1	Fungi		Ascomycota	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3roda__d2yvla___1	Metazoa		Chordata	Aquificae	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nicotinamide N-methyltransferase activity [GO:0008112]; pyridine N-methyltransferase activity [GO:0030760]; animal organ regeneration [GO:0031100]; methylation [GO:0032259]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]	tRNA (m1A) methyltransferase complex [GO:0031515]; tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]; tRNA methylation [GO:0030488]	animal organ regeneration [GO:0031100]; methylation [GO:0032259]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]	tRNA methylation [GO:0030488]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	tRNA (m1A) methyltransferase complex [GO:0031515]	nicotinamide N-methyltransferase activity [GO:0008112]; pyridine N-methyltransferase activity [GO:0030760]	tRNA (adenine-N1-)-methyltransferase activity [GO:0016429]
d3roda__d5p98a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nicotinamide N-methyltransferase activity [GO:0008112]; pyridine N-methyltransferase activity [GO:0030760]; animal organ regeneration [GO:0031100]; methylation [GO:0032259]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	animal organ regeneration [GO:0031100]; methylation [GO:0032259]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	nicotinamide N-methyltransferase activity [GO:0008112]; pyridine N-methyltransferase activity [GO:0030760]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d3roka__d3gh3b___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	plasma membrane [GO:0005886]; NAD glycohydrolase activity [GO:0061810]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; phosphorus-oxygen lyase activity [GO:0016849]; metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	metabolic process [GO:0008152]; positive regulation of B cell proliferation [GO:0030890]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD glycohydrolase activity [GO:0061810]; phosphorus-oxygen lyase activity [GO:0016849]
d3roka__d3zwpe___1	Metazoa	Metazoa	Chordata	Mollusca	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	cytoplasmic vesicle [GO:0031410]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]
d3rp2a__d4os5a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]		blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d3rp2b__d2ducb___1	Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3rp2b__d2vipa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; serine-type endopeptidase activity [GO:0004252]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]		blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d3rpba__d1ugka1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cholinergic synapse [GO:0098981]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extrinsic component of membrane [GO:0019898]; extrinsic component of synaptic vesicle membrane [GO:0098850]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphate ion binding [GO:0042301]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; selenium binding [GO:0008430]; zinc ion binding [GO:0008270]; brain development [GO:0007420]; dendritic spine organization [GO:0097061]; intracellular protein transport [GO:0006886]; regulation of NMDA receptor activity [GO:2000310]	astrocyte projection [GO:0097449]; axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dense core granule membrane [GO:0032127]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; integral component of Golgi membrane [GO:0030173]; integral component of neuronal dense core vesicle membrane [GO:0099066]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular membrane-bounded organelle [GO:0043231]; microvesicle [GO:1990742]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; clathrin binding [GO:0030276]; phosphatidylserine binding [GO:0001786]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]; brain development [GO:0007420]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; memory [GO:0007613]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of catecholamine secretion [GO:0033604]; negative regulation of dense core granule exocytosis [GO:1905414]; negative regulation of protein secretion [GO:0050709]; negative regulation of retrograde trans-synaptic signaling by neuropeptide [GO:1905433]; negative regulation of short-term neuronal synaptic plasticity [GO:0048174]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; negative regulation of vesicle fusion [GO:0031339]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendrite extension [GO:1903861]; positive regulation of dense core granule exocytosis [GO:1905415]; positive regulation of glutamate secretion [GO:0014049]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of endocytosis [GO:0030100]; regulation of presynaptic dense core granule exocytosis [GO:0099161]; secretory granule maturation [GO:0061792]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; vesicle fusion with vesicle [GO:0061782]; vesicle-mediated transport [GO:0016192]	brain development [GO:0007420]; dendritic spine organization [GO:0097061]; intracellular protein transport [GO:0006886]; regulation of NMDA receptor activity [GO:2000310]	brain development [GO:0007420]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; memory [GO:0007613]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of catecholamine secretion [GO:0033604]; negative regulation of dense core granule exocytosis [GO:1905414]; negative regulation of protein secretion [GO:0050709]; negative regulation of retrograde trans-synaptic signaling by neuropeptide [GO:1905433]; negative regulation of short-term neuronal synaptic plasticity [GO:0048174]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; negative regulation of vesicle fusion [GO:0031339]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendrite extension [GO:1903861]; positive regulation of dense core granule exocytosis [GO:1905415]; positive regulation of glutamate secretion [GO:0014049]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of endocytosis [GO:0030100]; regulation of presynaptic dense core granule exocytosis [GO:0099161]; secretory granule maturation [GO:0061792]; trans-synaptic signaling by BDNF, modulating synaptic transmission [GO:0099183]; vesicle fusion with vesicle [GO:0061782]; vesicle-mediated transport [GO:0016192]	cell junction [GO:0030054]; cholinergic synapse [GO:0098981]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extrinsic component of membrane [GO:0019898]; extrinsic component of synaptic vesicle membrane [GO:0098850]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]	astrocyte projection [GO:0097449]; axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dense core granule membrane [GO:0032127]; exocytic vesicle [GO:0070382]; glutamatergic synapse [GO:0098978]; integral component of Golgi membrane [GO:0030173]; integral component of neuronal dense core vesicle membrane [GO:0099066]; integral component of synaptic vesicle membrane [GO:0030285]; intracellular membrane-bounded organelle [GO:0043231]; microvesicle [GO:1990742]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; neuron projection terminus [GO:0044306]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphate ion binding [GO:0042301]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; selenium binding [GO:0008430]; zinc ion binding [GO:0008270]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; clathrin binding [GO:0030276]; phosphatidylserine binding [GO:0001786]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; SNARE binding [GO:0000149]; syntaxin-1 binding [GO:0017075]; syntaxin-3 binding [GO:0030348]
d3rpba__d5bugd2__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cholinergic synapse [GO:0098981]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extrinsic component of membrane [GO:0019898]; extrinsic component of synaptic vesicle membrane [GO:0098850]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; calcium ion binding [GO:0005509]; calcium-dependent phospholipid binding [GO:0005544]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphate ion binding [GO:0042301]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; selenium binding [GO:0008430]; zinc ion binding [GO:0008270]; brain development [GO:0007420]; dendritic spine organization [GO:0097061]; intracellular protein transport [GO:0006886]; regulation of NMDA receptor activity [GO:2000310]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; ubiquitin-specific protease binding [GO:1990381]; adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axon regeneration [GO:0048681]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	brain development [GO:0007420]; dendritic spine organization [GO:0097061]; intracellular protein transport [GO:0006886]; regulation of NMDA receptor activity [GO:2000310]	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; cellular response to nerve growth factor stimulus [GO:1990090]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of keratinocyte migration [GO:0051548]; negative regulation of myelination [GO:0031642]; negative regulation of neuron projection development [GO:0010977]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of potassium ion transmembrane transporter activity [GO:1901017]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of signaling receptor activity [GO:2000272]; negative regulation of synaptic vesicle clustering [GO:2000808]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein deubiquitination [GO:0016579]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of B cell apoptotic process [GO:0002902]; regulation of cellular component size [GO:0032535]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to estradiol [GO:0032355]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cell junction [GO:0030054]; cholinergic synapse [GO:0098981]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extrinsic component of membrane [GO:0019898]; extrinsic component of synaptic vesicle membrane [GO:0098850]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]	apical plasma membrane [GO:0016324]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; myelin sheath adaxonal region [GO:0035749]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; postsynaptic cytosol [GO:0099524]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; inositol 1,4,5 trisphosphate binding [GO:0070679]; phosphate ion binding [GO:0042301]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phospholipid binding [GO:0005543]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; selenium binding [GO:0008430]; zinc ion binding [GO:0008270]	anaphase-promoting complex binding [GO:0010997]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity [GO:0051717]; ionotropic glutamate receptor binding [GO:0035255]; lipid binding [GO:0008289]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity [GO:0051800]; phosphatidylinositol-3-phosphatase activity [GO:0004438]; phosphoprotein phosphatase activity [GO:0004721]; platelet-derived growth factor receptor binding [GO:0005161]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; ubiquitin-specific protease binding [GO:1990381]
d3rpil1_d3u1sl2__1												
d3rpna__d4yqma1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d3rpnb__d4nhzh1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	transferase activity [GO:0016740]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]	transferase activity [GO:0016740]
d3rpnc__d3wgde1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; isomerase activity [GO:0016853]; apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]	isomerase activity [GO:0016853]
d3rpnc__d4wf5a___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cell [GO:0005623]; periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cell [GO:0005623]; periplasmic space [GO:0042597]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]
d3rpne__d1fg4b___1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cell [GO:0005623]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]	
d3rpqb1_d3pnab___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]
d3rq2a1_d2c49b___1			Firmicutes	Euryarchaeota	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]; nicotinamide nucleotide metabolic process [GO:0046496]	ATP binding [GO:0005524]; inosine kinase activity [GO:0008906]; magnesium ion binding [GO:0000287]; nucleoside kinase activity [GO:0019206]	nicotinamide nucleotide metabolic process [GO:0046496]				ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]	ATP binding [GO:0005524]; inosine kinase activity [GO:0008906]; magnesium ion binding [GO:0000287]; nucleoside kinase activity [GO:0019206]
d3rqvc__d4niac___1						viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d3rqvj__d4niaj___1						viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d3rqvm__d4niak___1						viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d3rqvt__d4oq9k___1						viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d3rqvz__d4oq9c___1						viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d3rrea2_d2dcnc___1			Thermotogae	Crenarchaeota	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]; nicotinamide nucleotide metabolic process [GO:0046496]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]	nicotinamide nucleotide metabolic process [GO:0046496]				ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; nucleotide binding [GO:0000166]
d3rrfa2_d5c40b1__1		Metazoa	Thermotogae	Chordata	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]; nicotinamide nucleotide metabolic process [GO:0046496]	cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]	nicotinamide nucleotide metabolic process [GO:0046496]	D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]		cytosol [GO:0005829]; nucleus [GO:0005634]	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d3rroa__d3r3sb___1			Proteobacteria	Proteobacteria	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; oxidation-reduction process [GO:0055114]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]			3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3rrpb__d3gtda___1			Actinobacteria	Proteobacteria	tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle enzyme complex [GO:0045239]	tricarboxylic acid cycle enzyme complex [GO:0045239]	fumarate hydratase activity [GO:0004333]	fumarate hydratase activity [GO:0004333]
d3rrva__d1tyfa___1			Actinobacteria	Proteobacteria	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3rrvb1_d3h0qb1__1		Fungi	Actinobacteria	Ascomycota	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]		acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]		acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d3rrvc__d2fbma1__1		Metazoa	Actinobacteria	Chordata	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	nucleus [GO:0005634]; histone acetyltransferase activity [GO:0004402]; methylated histone binding [GO:0035064]; transcription corepressor activity [GO:0003714]; spermatogenesis [GO:0007283]		spermatogenesis [GO:0007283]		nucleus [GO:0005634]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	histone acetyltransferase activity [GO:0004402]; methylated histone binding [GO:0035064]; transcription corepressor activity [GO:0003714]
d3rrvd__d4zu2a___1			Actinobacteria	Proteobacteria	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; isoprenoid catabolic process [GO:0008300]; terpene catabolic process [GO:0046247]		isoprenoid catabolic process [GO:0008300]; terpene catabolic process [GO:0046247]			catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]
d3rrya__d3n2ib___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; nucleobase-containing small molecule interconversion [GO:0015949]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; nucleobase-containing small molecule interconversion [GO:0015949]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]
d3rs1b__d4zetb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; natural killer cell lectin-like receptor binding [GO:0046703]; transmembrane signaling receptor activity [GO:0004888]; membrane raft assembly [GO:0001765]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of immunological synapse formation [GO:2000522]; receptor clustering [GO:0043113]; regulation of actin filament polymerization [GO:0030833]; regulation of interleukin-2 biosynthetic process [GO:0045076]; regulation of T cell proliferation [GO:0042129]; T cell receptor signaling pathway [GO:0050852]	ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; tertiary granule membrane [GO:0070821]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; adaptive immune response [GO:0002250]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	membrane raft assembly [GO:0001765]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of immunological synapse formation [GO:2000522]; receptor clustering [GO:0043113]; regulation of actin filament polymerization [GO:0030833]; regulation of interleukin-2 biosynthetic process [GO:0045076]; regulation of T cell proliferation [GO:0042129]; T cell receptor signaling pathway [GO:0050852]	adaptive immune response [GO:0002250]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; tertiary granule membrane [GO:0070821]	carbohydrate binding [GO:0030246]; natural killer cell lectin-like receptor binding [GO:0046703]; transmembrane signaling receptor activity [GO:0004888]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3rs5a__d2j7pb2__1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	signal recognition particle [GO:0048500]; 7S RNA binding [GO:0008312]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	signal recognition particle [GO:0048500]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	7S RNA binding [GO:0008312]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d3rsed1_d3ukuf___1	Metazoa	Metazoa	Chordata	Chordata	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	actin filament binding [GO:0051015]	actin filament binding [GO:0051015]
d3rsga2_d5bydb1__1		Metazoa	Thermotogae	Chordata	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]; nicotinamide nucleotide metabolic process [GO:0046496]	cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]	nicotinamide nucleotide metabolic process [GO:0046496]	D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]		cytosol [GO:0005829]; nucleus [GO:0005634]	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d3rsjb1_d3wvja___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; membrane [GO:0016020]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	licheninase activity [GO:0042972]; polysaccharide catabolic process [GO:0000272]	negative regulation of neurotransmitter secretion [GO:0046929]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; membrane [GO:0016020]		lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	licheninase activity [GO:0042972]
d3rsjd1_d1ovwc___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; membrane [GO:0016020]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	negative regulation of neurotransmitter secretion [GO:0046929]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; membrane [GO:0016020]		lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]	cellulase activity [GO:0008810]
d3rsma3_d5f9ca1__1		Metazoa	Proteobacteria	Chordata	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d3rsma4_d1c47b4__1		Metazoa	Proteobacteria	Chordata	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]; alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	sarcoplasmic reticulum [GO:0016529]; magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; glucose metabolic process [GO:0006006]	alginic acid biosynthetic process [GO:0042121]; GDP-mannose biosynthetic process [GO:0009298]; lipopolysaccharide core region biosynthetic process [GO:0009244]; O antigen biosynthetic process [GO:0009243]; pathogenesis [GO:0009405]	glucose metabolic process [GO:0006006]		sarcoplasmic reticulum [GO:0016529]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]; phosphomannomutase activity [GO:0004615]	magnesium ion binding [GO:0000287]; phosphoglucomutase activity [GO:0004614]
d3rsoa__d1ex6b___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; guanylate kinase activity [GO:0004385]; GDP biosynthetic process [GO:0046711]; purine nucleotide metabolic process [GO:0006163]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	GDP biosynthetic process [GO:0046711]; purine nucleotide metabolic process [GO:0006163]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]	ATP binding [GO:0005524]; guanylate kinase activity [GO:0004385]
d3rt3b1_d1jrua___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cell [GO:0005623]; chromosome [GO:0005694]; cytosol [GO:0005829]; Golgi stack [GO:0005795]; intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; spindle pole centrosome [GO:0031616]; VCP-NSFL1C complex [GO:1990730]; ATPase binding [GO:0051117]; lipid binding [GO:0008289]; ubiquitin binding [GO:0043130]; autophagosome assembly [GO:0000045]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; negative regulation of protein localization to centrosome [GO:1904780]; nuclear envelope reassembly [GO:0031468]; positive regulation of mitotic centrosome separation [GO:0046604]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	autophagosome assembly [GO:0000045]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; negative regulation of protein localization to centrosome [GO:1904780]; nuclear envelope reassembly [GO:0031468]; positive regulation of mitotic centrosome separation [GO:0046604]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; chromosome [GO:0005694]; cytosol [GO:0005829]; Golgi stack [GO:0005795]; intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; spindle pole centrosome [GO:0031616]; VCP-NSFL1C complex [GO:1990730]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	ATPase binding [GO:0051117]; lipid binding [GO:0008289]; ubiquitin binding [GO:0043130]
d3rt3b2_d2z0db___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endomembrane system [GO:0012505]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; neuronal cell body [GO:0043025]; microtubule binding [GO:0008017]; protein domain specific binding [GO:0019904]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]; positive regulation of protein binding [GO:0032092]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]; positive regulation of protein binding [GO:0032092]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endomembrane system [GO:0012505]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; neuronal cell body [GO:0043025]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	microtubule binding [GO:0008017]; protein domain specific binding [GO:0019904]; tubulin binding [GO:0015631]; ubiquitin protein ligase binding [GO:0031625]
d3rt8a__d2y7rh___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3rt8a__d5cmba___1	Metazoa	Metazoa	Chordata	Ctenophora (ctenophores)	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ionotropic glutamate receptor activity [GO:0004970]	modulation of chemical synaptic transmission [GO:0050804]; regulation of receptor recycling [GO:0001919]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; synaptic cleft [GO:0043083]; terminal bouton [GO:0043195]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; PDZ domain binding [GO:0030165]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ionotropic glutamate receptor activity [GO:0004970]
d3rt9a2_d5byfa1__1		Metazoa	Thermotogae	Chordata	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]; nicotinamide nucleotide metabolic process [GO:0046496]	cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]	nicotinamide nucleotide metabolic process [GO:0046496]	D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]		cytosol [GO:0005829]; nucleus [GO:0005634]	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d3rtca2_d1c3qc1__1			Thermotogae	Firmicutes	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]; nicotinamide nucleotide metabolic process [GO:0046496]	ATP binding [GO:0005524]; hydroxyethylthiazole kinase activity [GO:0004417]; magnesium ion binding [GO:0000287]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	nicotinamide nucleotide metabolic process [GO:0046496]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]			ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]	ATP binding [GO:0005524]; hydroxyethylthiazole kinase activity [GO:0004417]; magnesium ion binding [GO:0000287]
d3rtea2_d2pkfa1__1			Thermotogae	Actinobacteria	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]; nicotinamide nucleotide metabolic process [GO:0046496]	plasma membrane [GO:0005886]; adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; carbohydrate kinase activity [GO:0019200]; dGTP binding [GO:0032567]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]	nicotinamide nucleotide metabolic process [GO:0046496]	AMP salvage [GO:0044209]; purine ribonucleoside salvage [GO:0006166]		plasma membrane [GO:0005886]	ADP-dependent NAD(P)H-hydrate dehydratase activity [GO:0052855]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; NADHX epimerase activity [GO:0052856]; NADPHX epimerase activity [GO:0052857]	adenosine kinase activity [GO:0004001]; ATP binding [GO:0005524]; carbohydrate kinase activity [GO:0019200]; dGTP binding [GO:0032567]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]
d3rtfd__d1o7tc___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	metal ion binding [GO:0046872]; transmembrane transport [GO:0055085]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	transmembrane transport [GO:0055085]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	metal ion binding [GO:0046872]
d3rtfd__d3ir1d___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d3rtff__d2qs4d___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d3rtia__d4za3a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3rtla1_d4fc3e___1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	pathogenesis [GO:0009405]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3rtld1_d3qzma1__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]	pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	cell wall [GO:0005618]; extracellular region [GO:0005576]	heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3rtld1_d3vtmb___1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme binding [GO:0020037]	pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	heme transporter activity [GO:0015232]; metal ion binding [GO:0046872]	heme binding [GO:0020037]
d3rtqb__d2gqha1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]
d3rtqd2_d5ujtd2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3rtua__d3b7ux3__1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]		aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3rtva1_d4fk4a1__1			Deinococcus-Thermus		DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]			DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d3rtwf__d3fvna___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3ru8x1_d1oc5a___1	Metazoa	Fungi	Chordata	Ascomycota	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cellulose catabolic process [GO:0030245]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d3rugb__d2e7lb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3rugb__d2rcji2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3rugf1_d1rzfl2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3rugg1_d3iu4l1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3rugh1_d1efxd2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ruib__d2xk5b___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of phagophore assembly site membrane [GO:0097632]; membrane [GO:0016020]; mitochondrion [GO:0005739]; phagophore assembly site [GO:0000407]; Atg12 activating enzyme activity [GO:0019778]; Atg8 activating enzyme activity [GO:0019779]; identical protein binding [GO:0042802]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; C-terminal protein lipidation [GO:0006501]; cellular response to nitrogen starvation [GO:0006995]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; piecemeal microautophagy of the nucleus [GO:0034727]; protein modification by small protein conjugation [GO:0032446]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; C-terminal protein lipidation [GO:0006501]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; piecemeal microautophagy of the nucleus [GO:0034727]; protein modification by small protein conjugation [GO:0032446]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of phagophore assembly site membrane [GO:0097632]; membrane [GO:0016020]; mitochondrion [GO:0005739]; phagophore assembly site [GO:0000407]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]	Atg12 activating enzyme activity [GO:0019778]; Atg8 activating enzyme activity [GO:0019779]; identical protein binding [GO:0042802]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d3ruib__d3x0wb1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of phagophore assembly site membrane [GO:0097632]; membrane [GO:0016020]; mitochondrion [GO:0005739]; phagophore assembly site [GO:0000407]; Atg12 activating enzyme activity [GO:0019778]; Atg8 activating enzyme activity [GO:0019779]; identical protein binding [GO:0042802]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; C-terminal protein lipidation [GO:0006501]; cellular response to nitrogen starvation [GO:0006995]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; piecemeal microautophagy of the nucleus [GO:0034727]; protein modification by small protein conjugation [GO:0032446]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; C-terminal protein lipidation [GO:0006501]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; piecemeal microautophagy of the nucleus [GO:0034727]; protein modification by small protein conjugation [GO:0032446]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of phagophore assembly site membrane [GO:0097632]; membrane [GO:0016020]; mitochondrion [GO:0005739]; phagophore assembly site [GO:0000407]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	Atg12 activating enzyme activity [GO:0019778]; Atg8 activating enzyme activity [GO:0019779]; identical protein binding [GO:0042802]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d3ruob1_d3snba___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3ruza__d3e5sb___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3rv2a3_d1o93a2__1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]
d3rv2b1_d1rg9c3__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d3rv2b2_d2hj2a1__1			Actinobacteria		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]		one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]	
d3rv3a1_d4c5aa1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]
d3rv3b3_d2dzdb3__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]
d3rv4a3_d5vevb3__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylamine-glycine ligase activity [GO:0004637]
d3rvhb__d5gjad___1	Metazoa	Viridiplantae	Chordata	Streptophyta	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cell wall [GO:0005618]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; 1-aminocyclopropane-1-carboxylate oxidase activity [GO:0009815]; copper ion binding [GO:0005507]; dioxygenase activity [GO:0051213]; L-ascorbic acid binding [GO:0031418]; cellular response to fatty acid [GO:0071398]; cellular response to nitric oxide [GO:0071732]; defense response [GO:0006952]; detection of ethylene stimulus [GO:0009727]; ethylene biosynthetic process [GO:0009693]; positive regulation of seed germination [GO:0010030]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cellular response to fatty acid [GO:0071398]; cellular response to nitric oxide [GO:0071732]; defense response [GO:0006952]; detection of ethylene stimulus [GO:0009727]; ethylene biosynthetic process [GO:0009693]; positive regulation of seed germination [GO:0010030]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell wall [GO:0005618]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	1-aminocyclopropane-1-carboxylate oxidase activity [GO:0009815]; copper ion binding [GO:0005507]; dioxygenase activity [GO:0051213]; L-ascorbic acid binding [GO:0031418]
d3rvhb__d5pjia___1	Metazoa	Metazoa	Chordata	Chordata	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d3rvja1_d1kmiy___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytosol [GO:0005829]	cytosol [GO:0005829]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d3rvja1_d3ltep1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	DNA binding [GO:0003677]; phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	DNA binding [GO:0003677]
d3rvjb1_d2mska___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	
d3rvka__d4zylb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	
d3rvoa__d5iulf___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]; protein dimerization activity [GO:0046983]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]		cytosol [GO:0005829]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphoprotein phosphatase activity [GO:0004721]; phosphorelay sensor kinase activity [GO:0000155]; protein dimerization activity [GO:0046983]
d3rvpb1_d2vuhb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d3rvra1_d4d6yb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d3rvsa1_d4hnsa1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]		acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]
d3rvtc1_d3qo1a1__1												
d3rvuc1_d6b0wl1__1												
d3rvvc1_d5d72l2__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]		cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]	cysteine-type peptidase activity [GO:0008234]	cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]
d3rvvc2_d4hcrn2__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; integrin binding involved in cell-matrix adhesion [GO:0098640]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]		cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	extracellular region [GO:0005576]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cysteine-type peptidase activity [GO:0008234]	integrin binding involved in cell-matrix adhesion [GO:0098640]
d3rvvc2_d5d5me1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cysteine-type peptidase activity [GO:0008234]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3rvxc1_d5i1dl1__1	Metazoa		Arthropoda		extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]				extracellular region [GO:0005576]		cysteine-type peptidase activity [GO:0008234]	
d3rvxc2_d3c08h2__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cysteine-type peptidase activity [GO:0008234]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3rw7a1_d2do4a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	ASAP complex [GO:0061574]; Cajal body [GO:0015030]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone binding [GO:0042393]; RNA binding [GO:0003723]; U4 snRNA binding [GO:0030621]; U6 snRNA binding [GO:0017070]; U6atac snRNA binding [GO:0030624]; ubiquitin-specific protease binding [GO:1990381]; cell morphogenesis [GO:0000902]; hematopoietic stem cell proliferation [GO:0071425]; homeostasis of number of cells [GO:0048872]; mRNA splicing, via spliceosome [GO:0000398]; nucleosome assembly [GO:0006334]; positive regulation of histone deubiquitination [GO:1903586]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; spliceosomal tri-snRNP complex assembly [GO:0000244]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cell morphogenesis [GO:0000902]; hematopoietic stem cell proliferation [GO:0071425]; homeostasis of number of cells [GO:0048872]; mRNA splicing, via spliceosome [GO:0000398]; nucleosome assembly [GO:0006334]; positive regulation of histone deubiquitination [GO:1903586]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; RNA splicing [GO:0008380]; spliceosomal snRNP assembly [GO:0000387]; spliceosomal tri-snRNP complex assembly [GO:0000244]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ASAP complex [GO:0061574]; Cajal body [GO:0015030]; cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	histone binding [GO:0042393]; RNA binding [GO:0003723]; U4 snRNA binding [GO:0030621]; U6atac snRNA binding [GO:0030624]; U6 snRNA binding [GO:0017070]; ubiquitin-specific protease binding [GO:1990381]
d3rw7c2_d1otoa___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]; pathogenesis [GO:0009405]	mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; viral process [GO:0016032]	pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell surface [GO:0009986]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	heparin binding [GO:0008201]; lipid binding [GO:0008289]; metal ion binding [GO:0046872]
d3rw8a__d1d6qa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3rwbb__d4bl5k___1		Metazoa	Proteobacteria	Chordata	pyridoxal 4-dehydrogenase activity [GO:0050235]; vitamin B6 catabolic process [GO:0042820]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	vitamin B6 catabolic process [GO:0042820]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	pyridoxal 4-dehydrogenase activity [GO:0050235]	coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]
d3rwbc__d2v6mc1__1			Proteobacteria	Deinococcus-Thermus	pyridoxal 4-dehydrogenase activity [GO:0050235]; vitamin B6 catabolic process [GO:0042820]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	vitamin B6 catabolic process [GO:0042820]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	pyridoxal 4-dehydrogenase activity [GO:0050235]	L-lactate dehydrogenase activity [GO:0004459]
d3rwsa1_d2k7ha___1		Viridiplantae		Streptophyta		cytoplasm [GO:0005737]; nucleus [GO:0005634]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; regulation of protein serine/threonine phosphatase activity [GO:0080163]; response to biotic stimulus [GO:0009607]		abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; regulation of protein serine/threonine phosphatase activity [GO:0080163]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]; nucleus [GO:0005634]		abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d3rxaa__d3q3yb1__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3rxfa__d1bt7a1__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3rxfa__d1tgsz___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3rxga__d1p05a___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d3rxia__d4gawe___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; membrane [GO:0016020]; serine-type endopeptidase activity [GO:0004252]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	digestion [GO:0007586]; proteolysis [GO:0006508]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasm [GO:0005737]; membrane [GO:0016020]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d3rxka__d4wmeb___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]
d3rxma__d1p11e___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d3rxoa__d1sgca___1	Metazoa		Chordata	Actinobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d3rxva__d3m7ua___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d3ry2b__d3szhf___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3ry4a2_d1j89c2__1	Metazoa	Metazoa	Chordata	Chordata	Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]	Fc-epsilon receptor signaling pathway [GO:0038095]	Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	IgG binding [GO:0019864]	IgE binding [GO:0019863]
d3ry5a1_d4d9rl2__1	Metazoa	Metazoa	Chordata	Chordata	Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; neutrophil degranulation [GO:0043312]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	IgG binding [GO:0019864]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ry7a__d1rfua___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]; pyridoxal 5'-phosphate salvage [GO:0009443]	D-ribose catabolic process [GO:0019303]	pyridoxal 5'-phosphate salvage [GO:0009443]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pyridoxal kinase activity [GO:0008478]
d3rycb2_d3wglb2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]; tubulin binding [GO:0015631]; microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	tubulin binding [GO:0015631]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d3ryhc2_d5m7ga2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]; tubulin binding [GO:0015631]; microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	tubulin binding [GO:0015631]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d3ryhd1_d1z2bb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]; tubulin binding [GO:0015631]; microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	tubulin binding [GO:0015631]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d3ryid2_d5h5gb2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]; tubulin binding [GO:0015631]; microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	tubulin binding [GO:0015631]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d3rykb1_d4aq6h___1			Firmicutes	Proteobacteria	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]; O antigen biosynthetic process [GO:0009243]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	dTDP-rhamnose biosynthetic process [GO:0019305]; O antigen biosynthetic process [GO:0009243]	L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]		protein-DNA complex [GO:0032993]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3rymc__d2cbpa___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3rypa1_d2bgcb2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; pathogenesis [GO:0009405]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	pathogenesis [GO:0009405]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3ryrb2_d5cvuc1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; protein-DNA complex [GO:0032993]		cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]
d3ryxb__d3iaia1__1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; morphogenesis of an epithelium [GO:0002009]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to drug [GO:0042493]; response to testosterone [GO:0033574]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	basolateral plasma membrane [GO:0016323]; integral component of membrane [GO:0016021]; microvillus membrane [GO:0031528]; nucleolus [GO:0005730]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3rz2a__d3ezzd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; cell cycle [GO:0007049]; multicellular organism development [GO:0007275]; positive regulation of cell migration [GO:0030335]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; MAP kinase serine/threonine phosphatase activity [GO:1990439]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]	cell cycle [GO:0007049]; multicellular organism development [GO:0007275]; positive regulation of cell migration [GO:0030335]	dephosphorylation [GO:0016311]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]	cytoplasm [GO:0005737]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; spindle [GO:0005819]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]	MAP kinase serine/threonine phosphatase activity [GO:1990439]; MAP kinase tyrosine/serine/threonine phosphatase activity [GO:0017017]; phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine/threonine phosphatase activity [GO:0008330]; protein tyrosine phosphatase activity [GO:0004725]
d3rzca1_d4huva1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3rzcc1_d3pwpe2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3rzcd1_d3cfki2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3rzcd2_d1uywm1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3rzub__d2znra1__1	Metazoa	Metazoa	Chordata	Chordata	cleavage furrow [GO:0032154]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; Lys63-specific deubiquitinase activity [GO:0061578]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; protein domain specific binding [GO:0019904]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; mitotic cytokinesis [GO:0000281]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of cell population proliferation [GO:0008284]; protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536]; receptor signaling pathway via JAK-STAT [GO:0007259]	cytosol [GO:0005829]; endosome [GO:0005768]; membrane [GO:0016020]; Lys63-specific deubiquitinase activity [GO:0061578]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536]	mitotic cytokinesis [GO:0000281]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of cell population proliferation [GO:0008284]; protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536]; receptor signaling pathway via JAK-STAT [GO:0007259]	protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536]	cleavage furrow [GO:0032154]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; endosome [GO:0005768]; membrane [GO:0016020]	Lys63-specific deubiquitinase activity [GO:0061578]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; protein domain specific binding [GO:0019904]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]	Lys63-specific deubiquitinase activity [GO:0061578]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]
d3rzwd__d4a20a___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]; cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]	polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]
d3s0cd__d2qapc___1			Euryarchaeota		cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]		aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	fructose-bisphosphate aldolase activity [GO:0004332]
d3s0na__d3snaa___1	Metazoa		Chordata		cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]; peptide binding [GO:0042277]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; angiotensin maturation [GO:0002003]; basement membrane disassembly [GO:0034769]; cellular response to glucose stimulus [GO:0071333]; extracellular matrix disassembly [GO:0022617]; interleukin-1 beta biosynthetic process [GO:0050720]; midbrain development [GO:0030901]; positive regulation of angiogenesis [GO:0045766]; regulation of inflammatory response [GO:0050727]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	angiotensin maturation [GO:0002003]; basement membrane disassembly [GO:0034769]; cellular response to glucose stimulus [GO:0071333]; extracellular matrix disassembly [GO:0022617]; interleukin-1 beta biosynthetic process [GO:0050720]; midbrain development [GO:0030901]; positive regulation of angiogenesis [GO:0045766]; regulation of inflammatory response [GO:0050727]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cell [GO:0005623]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; secretory granule [GO:0030141]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	peptide binding [GO:0042277]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3s11a1_d5xldb___1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d3s1ca1_d2bvhc2__1	Viridiplantae		Streptophyta	Actinobacteria	extracellular space [GO:0005615]; cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]	cytokinin metabolic process [GO:0009690]		extracellular space [GO:0005615]		cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]	(R)-6-hydroxynicotine oxidase activity [GO:0018530]; FAD binding [GO:0071949]
d3s1da1_d1ffuc2__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular space [GO:0005615]; cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytokinin metabolic process [GO:0009690]		extracellular space [GO:0005615]		cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3s1ea1_d1ahvb2__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	extracellular space [GO:0005615]; cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]; cytokinin metabolic process [GO:0009690]	peroxisome [GO:0005777]; FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]; methanol metabolic process [GO:0015945]	cytokinin metabolic process [GO:0009690]	methanol metabolic process [GO:0015945]	extracellular space [GO:0005615]	peroxisome [GO:0005777]	cytokinin dehydrogenase activity [GO:0019139]; FAD binding [GO:0071949]	FAD binding [GO:0071949]; vanillyl-alcohol oxidase activity [GO:0018465]
d3s1jc__d1yhum___1		Metazoa	Verrucomicrobia	Annelida	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3s1ua__d2ehhd___1			Euryarchaeota	Aquificae	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3s1uc__d4ahqb1__1			Euryarchaeota	Firmicutes	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytosol [GO:0005829]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	N-acetylneuraminate lyase activity [GO:0008747]
d3s1uc__d4imeg___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	N-acetylneuraminate lyase activity [GO:0008747]
d3s1vb__d1ok4h___1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	fructose-bisphosphate aldolase activity [GO:0004332]
d3s1ve__d1zajd___1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]	I band [GO:0031674]; M band [GO:0031430]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	fructose-bisphosphate aldolase activity [GO:0004332]
d3s1wc__d4icnb___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3s1we__d2zdra2__1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	catalytic activity [GO:0003824]; carbohydrate biosynthetic process [GO:0016051]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	carbohydrate biosynthetic process [GO:0016051]	cytoplasm [GO:0005737]		aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	catalytic activity [GO:0003824]
d3s1xb__d4r53d___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3s1xd__d4imeh___1			Euryarchaeota	Proteobacteria	cytoplasm [GO:0005737]; aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	cytoplasm [GO:0005737]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	aldehyde-lyase activity [GO:0016832]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]	N-acetylneuraminate lyase activity [GO:0008747]
d3s2sb__d4l08a___1			Firmicutes	Proteobacteria	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	hydrolase activity [GO:0016787]					catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	hydrolase activity [GO:0016787]
d3s2sd__d3pl1a___1			Firmicutes	Actinobacteria	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nicotinamidase activity [GO:0008936]; antibiotic metabolic process [GO:0016999]; NAD salvage [GO:0034355]; nicotinamide metabolic process [GO:0006769]		antibiotic metabolic process [GO:0016999]; NAD salvage [GO:0034355]; nicotinamide metabolic process [GO:0006769]			catalytic activity [GO:0003824]; metal ion binding [GO:0046872]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; nicotinamidase activity [GO:0008936]
d3s2va__d1ms7c___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3s34l2_d1t6vn___1		Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3s37l1_d5i18l1__1	Metazoa		Chordata		cell junction [GO:0030054]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; sorting endosome [GO:0097443]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; growth factor binding [GO:0019838]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; angiogenesis [GO:0001525]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic hemopoiesis [GO:0035162]; endothelial cell differentiation [GO:0045446]; endothelium development [GO:0003158]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of gene expression [GO:0010629]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vasculogenesis [GO:2001214]; protein autophosphorylation [GO:0046777]; protein kinase B signaling [GO:0043491]; regulation of cell shape [GO:0008360]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral process [GO:0016032]		angiogenesis [GO:0001525]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic hemopoiesis [GO:0035162]; endothelial cell differentiation [GO:0045446]; endothelium development [GO:0003158]; ERK1 and ERK2 cascade [GO:0070371]; extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of gene expression [GO:0010629]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vasculogenesis [GO:2001214]; protein autophosphorylation [GO:0046777]; protein kinase B signaling [GO:0043491]; regulation of cell shape [GO:0008360]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]; viral process [GO:0016032]		cell junction [GO:0030054]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; sorting endosome [GO:0097443]		ATP binding [GO:0005524]; cadherin binding [GO:0045296]; growth factor binding [GO:0019838]; Hsp90 protein binding [GO:0051879]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]	
d3s3ea1_d1eeoa___1	Metazoa	Metazoa	Arthropoda	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; integral component of membrane [GO:0016021]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axon guidance [GO:0007411]; branching involved in open tracheal system development [GO:0060446]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	axon guidance [GO:0007411]; branching involved in open tracheal system development [GO:0060446]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	apical part of cell [GO:0045177]; axon [GO:0030424]; integral component of membrane [GO:0016021]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3s3eb1_d2f6va___1	Metazoa	Metazoa	Arthropoda	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; integral component of membrane [GO:0016021]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axon guidance [GO:0007411]; branching involved in open tracheal system development [GO:0060446]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	axon guidance [GO:0007411]; branching involved in open tracheal system development [GO:0060446]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	apical part of cell [GO:0045177]; axon [GO:0030424]; integral component of membrane [GO:0016021]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3s3fa1_d2qbqa___1	Metazoa	Metazoa	Arthropoda	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; integral component of membrane [GO:0016021]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axon guidance [GO:0007411]; branching involved in open tracheal system development [GO:0060446]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	axon guidance [GO:0007411]; branching involved in open tracheal system development [GO:0060446]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	apical part of cell [GO:0045177]; axon [GO:0030424]; integral component of membrane [GO:0016021]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3s3fb1_d1q6na1__1	Metazoa	Metazoa	Arthropoda	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; integral component of membrane [GO:0016021]; protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; axon guidance [GO:0007411]; branching involved in open tracheal system development [GO:0060446]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	axon guidance [GO:0007411]; branching involved in open tracheal system development [GO:0060446]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	apical part of cell [GO:0045177]; axon [GO:0030424]; integral component of membrane [GO:0016021]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein tyrosine phosphatase activity [GO:0004725]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3s3ga__d4gaca___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; synapse [GO:0045202]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; glucuronolactone reductase activity [GO:0047941]; L-glucuronate reductase activity [GO:0047939]; mevaldate reductase (NADPH) activity [GO:0019726]; oxidoreductase activity [GO:0016491]; aldehyde catabolic process [GO:0046185]; cellular detoxification of aldehyde [GO:0110095]; D-glucuronate catabolic process [GO:0042840]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; L-ascorbic acid biosynthetic process [GO:0019853]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	aldehyde catabolic process [GO:0046185]; cellular detoxification of aldehyde [GO:0110095]; daunorubicin metabolic process [GO:0044597]; D-glucuronate catabolic process [GO:0042840]; doxorubicin metabolic process [GO:0044598]; L-ascorbic acid biosynthetic process [GO:0019853]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; synapse [GO:0045202]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; glucuronolactone reductase activity [GO:0047941]; L-glucuronate reductase activity [GO:0047939]; mevaldate reductase (NADPH) activity [GO:0019726]; oxidoreductase activity [GO:0016491]
d3s3ra__d2hh5a___1	Metazoa	Metazoa	Platyhelminthes	Chordata	cysteine-type endopeptidase activity [GO:0004197]; regulation of catalytic activity [GO:0050790]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	regulation of catalytic activity [GO:0050790]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	cysteine-type endopeptidase activity [GO:0004197]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d3s43a__d1psaa___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]
d3s43b__d3pmua___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]
d3s44a__d1fu7a___1		Metazoa	Proteobacteria	Chordata	transferase activity, transferring glycosyl groups [GO:0016757]	skeletal muscle myofibril [GO:0098723]; glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]; glycogen metabolic process [GO:0005977]		glycogen metabolic process [GO:0005977]		skeletal muscle myofibril [GO:0098723]	transferase activity, transferring glycosyl groups [GO:0016757]	glycogen phosphorylase activity [GO:0008184]; linear malto-oligosaccharide phosphorylase activity [GO:0102250]; nucleotide binding [GO:0000166]; pyridoxal phosphate binding [GO:0030170]; SHG alpha-glucan phosphorylase activity [GO:0102499]
d3s47a1_d1l8pd2__1		Fungi	Firmicutes	Ascomycota	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cellular amino acid catabolic process [GO:0009063]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3s48a__d2e7db___1	Metazoa		Chordata	Firmicutes	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme binding [GO:0020037]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]
d3s48c__d2bv8e___1	Metazoa		Chordata	Rhodophyta	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3s4ma__d4hs5a___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	ferric iron binding [GO:0008199]; iron-sulfur cluster assembly [GO:0016226]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	iron-sulfur cluster assembly [GO:0016226]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]	ferric iron binding [GO:0008199]
d3s4yb1_d1ig3b2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; kinase activity [GO:0016301]; thiamine binding [GO:0030975]; thiamine diphosphokinase activity [GO:0004788]; thiamine diphosphate biosynthetic process [GO:0009229]; thiamine metabolic process [GO:0006772]; thiamine-containing compound metabolic process [GO:0042723]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; thiamine binding [GO:0030975]; thiamine diphosphokinase activity [GO:0004788]; thiamine diphosphate biosynthetic process [GO:0009229]; thiamine metabolic process [GO:0006772]	thiamine-containing compound metabolic process [GO:0042723]; thiamine diphosphate biosynthetic process [GO:0009229]; thiamine metabolic process [GO:0006772]	thiamine diphosphate biosynthetic process [GO:0009229]; thiamine metabolic process [GO:0006772]	cytosol [GO:0005829]		ATP binding [GO:0005524]; kinase activity [GO:0016301]; thiamine binding [GO:0030975]; thiamine diphosphokinase activity [GO:0004788]	ATP binding [GO:0005524]; kinase activity [GO:0016301]; thiamine binding [GO:0030975]; thiamine diphosphokinase activity [GO:0004788]
d3s53a__d5kqzb___1					aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]
d3s53a__d5p2da___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]
d3s53b__d3sfcb___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d3s54a__d5p11a___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; identical protein binding [GO:0042802]	aspartic-type endopeptidase activity [GO:0004190]
d3s5ea__d3iasq___1	Metazoa		Chordata	Deinococcus-Thermus	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]		cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]	quinone binding [GO:0048038]
d3s5fa__d4lp1a___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	ferric iron binding [GO:0008199]; iron-sulfur cluster assembly [GO:0016226]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	iron-sulfur cluster assembly [GO:0016226]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]	ferric iron binding [GO:0008199]
d3s5fb__d3i9vh___1	Metazoa		Chordata	Deinococcus-Thermus	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]		cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]	quinone binding [GO:0048038]
d3s5yb1_d1jz8d5__1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	beta-galactosidase complex [GO:0009341]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3s5yb2_d2zxba2__1	Metazoa		Chordata	Thermotogae	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	lysosome [GO:0005764]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-L-fucosidase activity [GO:0004560]
d3s5za1_d6a3ha___1	Metazoa		Chordata	Firmicutes	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	cellulose catabolic process [GO:0030245]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]
d3s5zb2_d1cdga3__1	Metazoa		Chordata	Firmicutes	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular region [GO:0005576]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3s66a__d4fh7a___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d3s66a__d4l1eh___1	Metazoa		Chordata	Cyanobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3s66b__d1yhub___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3s68a__d2br3b___1	Metazoa		Chordata	Actinobacteria	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	methyltransferase activity [GO:0008168]; lipid biosynthetic process [GO:0008610]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	lipid biosynthetic process [GO:0008610]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]		catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]	methyltransferase activity [GO:0008168]
d3s69a__d1gi9.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]		blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	extracellular region [GO:0005576]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	serine-type endopeptidase activity [GO:0004252]
d3s6ca1_d2fo4a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3s6ca1_d3esuf2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3s6ca3_d1fc2d1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3s6oa__d3czsa3__1		Metazoa	Proteobacteria	Arthropoda	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	carbohydrate metabolic process [GO:0005975]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]		endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d3s6oc__d3cl7b___1			Proteobacteria	Proteobacteria	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]
d3s6od__d2c1ga1__1			Proteobacteria	Firmicutes	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; carbohydrate metabolic process [GO:0005975]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pathogenesis [GO:0009405]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810]; metal ion binding [GO:0046872]
d3s7aa__d3kjra1__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]; dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	dTMP biosynthetic process [GO:0006231]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]		dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]	dihydrofolate reductase activity [GO:0004146]; nucleotide binding [GO:0000166]; thymidylate synthase activity [GO:0004799]
d3s7ga2_d1rzjl1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3s7gb1_d3ijsc1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3s7gc1_d1nfdc1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3s7gd1_d1um4h1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3s7gd1_d2j8ua1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3s7gd2_d3cafa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3s7na2_d1mkma2__1			Deinococcus-Thermus	Thermotogae	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3s7pa1_d3nhqb1__1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3s7pa1_d5svva___1		Viridiplantae	Deinococcus-Thermus	Streptophyta	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; photoreceptor activity [GO:0009881]; circadian rhythm [GO:0007623]; flower development [GO:0009908]; protein ubiquitination [GO:0016567]; protein-chromophore linkage [GO:0018298]; response to blue light [GO:0009637]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	circadian rhythm [GO:0007623]; flower development [GO:0009908]; protein-chromophore linkage [GO:0018298]; protein ubiquitination [GO:0016567]; response to blue light [GO:0009637]		cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	photoreceptor activity [GO:0009881]
d3s7qa2_d3c2wc1__1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3s82a1_d1o9tb2__1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]
d3s82a3_d5ugha1__1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d3s82b3_d1xrca3__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d3s85b__d5p4ta___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3s85f__d4fiva___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d3s85g__d4rvic___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3s85g__d5apre___1		Fungi		Mucoromycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3s85j__d2wkza___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3s85j__d3oqfa___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]
d3s85k__d3bgca___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3s85k__d5j25a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3s85l__d2iena___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3s86d__d2mjpb___1			Thermotogae	Euryarchaeota	cytosol [GO:0005829]; metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	dITP diphosphatase activity [GO:0035870]; ITP diphosphatase activity [GO:0036220]; metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; XTP diphosphatase activity [GO:0036222]; nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleoside triphosphate catabolic process [GO:0009143]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	cytosol [GO:0005829]		metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]	dITP diphosphatase activity [GO:0035870]; ITP diphosphatase activity [GO:0036220]; metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; XTP diphosphatase activity [GO:0036222]
d3s8hb__d4s2ca___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; membrane [GO:0016020]; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [GO:0004801]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]
d3s8hb__d4wozh___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	N-acetylneuraminate lyase activity [GO:0008747]
d3s8la__d1r1qb1__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3 domain binding [GO:0017124]; SH3/SH2 adaptor activity [GO:0005070]; aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; axon guidance [GO:0007411]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell-cell signaling [GO:0007267]; cellular response to ionizing radiation [GO:0071479]; cytokine-mediated signaling pathway [GO:0019221]; entry of bacterium into host cell [GO:0035635]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; fibroblast growth factor receptor signaling pathway [GO:0008543]; insulin receptor signaling pathway [GO:0008286]; interleukin-15-mediated signaling pathway [GO:0035723]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]; T cell costimulation [GO:0031295]; viral process [GO:0016032]		cell-cell junction [GO:0005911]; COP9 signalosome [GO:0008180]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; Grb2-EGFR complex [GO:0070436]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ephrin receptor binding [GO:0046875]; epidermal growth factor receptor binding [GO:0005154]; identical protein binding [GO:0042802]; insulin receptor substrate binding [GO:0043560]; neurotrophin TRKA receptor binding [GO:0005168]; phosphotyrosine residue binding [GO:0001784]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; RNA binding [GO:0003723]; SH3/SH2 adaptor activity [GO:0005070]; SH3 domain binding [GO:0017124]	
d3s8qb__d4ia8b___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]	DNA binding [GO:0003677]					DNA binding [GO:0003677]	DNA binding [GO:0003677]
d3s8ra__d1h2g.1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; glutaryl-7-aminocephalosporanic-acid acylase activity [GO:0033968]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	glutaryl-7-aminocephalosporanic-acid acylase activity [GO:0033968]	metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]
d3s8ra__d5lajf___1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; glutaryl-7-aminocephalosporanic-acid acylase activity [GO:0033968]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	periplasmic space [GO:0042597]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	glutaryl-7-aminocephalosporanic-acid acylase activity [GO:0033968]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3s8rb__d1pnk.1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; glutaryl-7-aminocephalosporanic-acid acylase activity [GO:0033968]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	glutaryl-7-aminocephalosporanic-acid acylase activity [GO:0033968]	metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]
d3s8ya__d2gbcb2__1		Metazoa	Proteobacteria	Chordata	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]; formaldehyde catabolic process [GO:0046294]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]	formaldehyde catabolic process [GO:0046294]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]	collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3s90a1_d3s90b2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]
d3s90b1_d2b0ha1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]; cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	cell adhesion [GO:0007155]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; focal adhesion [GO:0005925]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]	actin filament binding [GO:0051015]; integrin binding [GO:0005178]; LIM domain binding [GO:0030274]; phosphatidylinositol binding [GO:0035091]; phosphatidylserine binding [GO:0001786]; structural constituent of cytoskeleton [GO:0005200]; vinculin binding [GO:0017166]
d3s91a__d4qy4a___1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357]	intermediate filament cytoskeleton [GO:0045111]; intracellular membrane-bounded organelle [GO:0043231]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SWI/SNF complex [GO:0016514]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; helicase activity [GO:0004386]; histone binding [GO:0042393]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]; ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; spermatid development [GO:0007286]	chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357]	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatid development [GO:0007286]	nucleus [GO:0005634]	intermediate filament cytoskeleton [GO:0045111]; intracellular membrane-bounded organelle [GO:0043231]; nBAF complex [GO:0071565]; npBAF complex [GO:0071564]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; SWI/SNF complex [GO:0016514]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	ATP binding [GO:0005524]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; helicase activity [GO:0004386]; histone binding [GO:0042393]; transcription coactivator activity [GO:0003713]; transcription regulatory region DNA binding [GO:0044212]
d3s96b1_d2pcpa2__1												
d3s97b__d1rj5a___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]	integral component of membrane [GO:0016021]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon dioxide transport [GO:0015670]; regulation of pH [GO:0006885]	cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]	carbon dioxide transport [GO:0015670]; regulation of pH [GO:0006885]	anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]	integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3s97b__d4uovf___1	Metazoa		Chordata	Aquificae	anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]		anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]		carbohydrate binding [GO:0030246]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3s97d1_d3qpqc2__1	Metazoa		Chordata		anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]		cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]		anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]		carbohydrate binding [GO:0030246]	
d3s97d1_d4elkd1__1	Metazoa		Chordata		anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]		cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]		anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]		carbohydrate binding [GO:0030246]	
d3s97d2_d1a1mb___1	Metazoa	Metazoa	Chordata	Chordata	anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	carbohydrate binding [GO:0030246]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3s97d2_d4gmsn1__1	Metazoa		Chordata	Negarnaviricota	anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]; carbohydrate binding [GO:0030246]; cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; neuron projection development [GO:0031175]; Notch signaling pathway [GO:0007219]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sodium ion transport [GO:0010765]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	anchored component of postsynaptic membrane [GO:0099025]; anchored component of presynaptic membrane [GO:0099026]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; membrane raft [GO:0045121]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	carbohydrate binding [GO:0030246]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d3s9aa__d3gylb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; sodium channel regulator activity [GO:0017080]; cornification [GO:0070268]; positive regulation of sodium ion transport [GO:0010765]		cornification [GO:0070268]; positive regulation of sodium ion transport [GO:0010765]	extracellular region [GO:0005576]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; sodium channel regulator activity [GO:0017080]
d3s9ha1_d2igib___1				Proteobacteria	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	cytosol [GO:0005829]; 3'-5'-exoribonuclease activity [GO:0000175]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; oligoribonucleotidase activity [GO:0034611]; single-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008310]; RNA catabolic process [GO:0006401]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	RNA catabolic process [GO:0006401]		cytosol [GO:0005829]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3'-5'-exoribonuclease activity [GO:0000175]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; oligoribonucleotidase activity [GO:0034611]; single-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008310]
d3s9oa__d2lk4a___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	apical dendrite [GO:0097440]; cell [GO:0005623]; cell body [GO:0044297]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; 3-phosphoinositide-dependent protein kinase binding [GO:0043423]; ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; NMDA glutamate receptor activity [GO:0004972]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein C-terminus binding [GO:0008022]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; ubiquitin protein ligase binding [GO:0031625]; activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein-containing complex assembly [GO:0065003]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of NMDA receptor activity [GO:2000310]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of synaptic plasticity [GO:0048167]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; integrin-mediated signaling pathway [GO:0007229]; interleukin-2-mediated signaling pathway [GO:0038110]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; protein-containing complex assembly [GO:0065003]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of NMDA receptor activity [GO:2000310]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of synaptic plasticity [GO:0048167]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]	apical dendrite [GO:0097440]; cell [GO:0005623]; cell body [GO:0044297]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; NMDA selective glutamate receptor complex [GO:0017146]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]	actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]	3-phosphoinositide-dependent protein kinase binding [GO:0043423]; ATP binding [GO:0005524]; calmodulin-dependent protein kinase activity [GO:0004683]; NMDA glutamate receptor activity [GO:0004972]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; protein tyrosine kinase activity [GO:0004713]; ubiquitin protein ligase binding [GO:0031625]
d3s9ua1_d4m6ja___1		Metazoa	Firmicutes	Chordata	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3s9ub1_d3fqfa___1			Firmicutes		dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	
d3s9yc__d4muza1__1			Apicomplexa	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3sa2b1_d5ispx___1			Firmicutes	Firmicutes	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3sa3a__d1qbub___1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3sa4b__d3vfaa___1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3sa4b__d4gidb___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3sa6b__d3kt2a1__1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3sa8b__d5ozwa___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d3sa9a__d1xn3b___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3sa9a__d4yhqa___1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3saaa__d5p4ca___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d3sabb__d1sh9a___1					aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3sabb__d3cibb___1		Metazoa		Chordata	aspartic-type endopeptidase activity [GO:0004190]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]		axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3saia1_d5istx___1			Firmicutes	Firmicutes	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3saib1_d3ntza___1		Metazoa	Firmicutes	Chordata	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]; axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; negative regulation of translation [GO:0017148]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; drug binding [GO:0008144]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]; sequence-specific mRNA binding [GO:1990825]; translation repressor activity, mRNA regulatory element binding [GO:0000900]
d3sala__d4ks1a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3salb__d2cmld___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3salb__d4b7ja___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3sana__d4h53a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3sanb__d4cpyb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3saob__d3fa9b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; extracellular space [GO:0005615]; arachidonic acid binding [GO:0050544]; fatty acid binding [GO:0005504]; linoleic acid binding [GO:0070539]; oleic acid binding [GO:0070538]; stearic acid binding [GO:0070540]; acute-phase response [GO:0006953]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular lipid metabolic process [GO:0044255]; cellular response to linoleic acid [GO:0071399]; chondrocyte differentiation [GO:0002062]; chondrocyte hypertrophy [GO:0003415]; defense response to bacterium [GO:0042742]; embryo development ending in birth or egg hatching [GO:0009792]; fatty acid homeostasis [GO:0055089]; fatty acid transport [GO:0015908]; heart development [GO:0007507]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; long-chain fatty acid transport [GO:0015909]; muscle fiber development [GO:0048747]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myotube differentiation [GO:0010831]; response to corticosterone [GO:0051412]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to linoleic acid [GO:0070543]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	acute-phase response [GO:0006953]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular lipid metabolic process [GO:0044255]; cellular response to linoleic acid [GO:0071399]; chondrocyte differentiation [GO:0002062]; chondrocyte hypertrophy [GO:0003415]; defense response to bacterium [GO:0042742]; embryo development ending in birth or egg hatching [GO:0009792]; fatty acid homeostasis [GO:0055089]; fatty acid transport [GO:0015908]; heart development [GO:0007507]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; long-chain fatty acid transport [GO:0015909]; muscle fiber development [GO:0048747]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myotube differentiation [GO:0010831]; response to corticosterone [GO:0051412]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to linoleic acid [GO:0070543]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell [GO:0005623]; extracellular space [GO:0005615]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	arachidonic acid binding [GO:0050544]; fatty acid binding [GO:0005504]; linoleic acid binding [GO:0070539]; oleic acid binding [GO:0070538]; stearic acid binding [GO:0070540]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3saxa__d1cnka___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3sb2d__d3qsud___1			Proteobacteria		RNA binding [GO:0003723]; regulation of transcription, DNA-templated [GO:0006355]		regulation of transcription, DNA-templated [GO:0006355]				RNA binding [GO:0003723]	
d3sb2e__d4nl3i___1			Proteobacteria	Firmicutes	RNA binding [GO:0003723]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; RNA binding [GO:0003723]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]	regulation of transcription, DNA-templated [GO:0006355]	regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation, ncRNA-mediated [GO:0045974]		cytosol [GO:0005829]	RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3sb5b1_d3l64a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3sb5c1_d4nwha___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3sb5d1_d4gn3g___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3sb8b1_d4h8za___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3sb9a1_d1ge0a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; cellular protein metabolic process [GO:0044267]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; neutrophil degranulation [GO:0043312]; retina homeostasis [GO:0001895]	host cell cytoplasm [GO:0030430]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	lysozyme activity [GO:0003796]	identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3sb9b1_d1lj3a___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3sbaa1_d1ks3a___1					host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3sbac1_d2ybha___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3sbcd__d1nw2a___1	Fungi		Ascomycota	Firmicutes	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]; identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]; cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]	cell [GO:0005623]	identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]	protein disulfide oxidoreductase activity [GO:0015035]
d3sbcf__d4wbjb___1	Fungi		Ascomycota	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]; identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]; cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]	cell [GO:0005623]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]	metal ion binding [GO:0046872]
d3sbcj__d1byed2__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]; identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]; cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	glutathione metabolic process [GO:0006749]; response to herbicide [GO:0009635]; response to hydrogen peroxide [GO:0042542]; response to reactive oxygen species [GO:0000302]; response to salicylic acid [GO:0009751]; response to xenobiotic stimulus [GO:0009410]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]	cytoplasm [GO:0005737]; protein-containing complex [GO:0032991]	identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d3sbfc1_d4ihch1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cellular amino acid catabolic process [GO:0009063]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			magnesium ion binding [GO:0000287]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d3sbfc2_d2ggeh1__1			Proteobacteria	Firmicutes	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	cellular amino acid catabolic process [GO:0009063]				magnesium ion binding [GO:0000287]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3sbfc2_d2rdxc2__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	metal ion binding [GO:0046872]	cellular amino acid catabolic process [GO:0009063]				magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]
d3sbpb2_d2xv0a___1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	oxidation-reduction process [GO:0055114]	membrane [GO:0016020]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3sbpb2_d3ppsd2__1		Fungi	Proteobacteria	Ascomycota	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]		membrane [GO:0016020]; periplasmic space [GO:0042597]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3sbpf2_d5ue6a1__1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	nitrogen compound metabolic process [GO:0006807]	membrane [GO:0016020]; periplasmic space [GO:0042597]		calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3sbpg2_d4e9qa2__1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	membrane [GO:0016020]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d3sbra2_d4e9ta2__1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	membrane [GO:0016020]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d3sbre2_d5d4ja1__1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	membrane [GO:0016020]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3sbrf2_d1et8a2__1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	membrane [GO:0016020]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3sbrg2_d1oowa___1		Viridiplantae	Proteobacteria	Streptophyta	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]		membrane [GO:0016020]; periplasmic space [GO:0042597]	chloroplast thylakoid membrane [GO:0009535]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3sbrh1_d2iwka1__1			Proteobacteria	Proteobacteria	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]	copper ion import [GO:0015677]; denitrification pathway [GO:0019333]	denitrification pathway [GO:0019333]	membrane [GO:0016020]; periplasmic space [GO:0042597]	membrane [GO:0016020]; periplasmic space [GO:0042597]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d3sbwb__d4g3yl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of T cell apoptotic process [GO:0070234]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of apoptotic process [GO:0043065]; positive regulation of T cell apoptotic process [GO:0070234]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]		cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d3sc6a__d1ybva___1		Fungi	Firmicutes	Ascomycota	dTDP-4-dehydrorhamnose reductase activity [GO:0008831]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]	tetrahydroxynaphthalene reductase activity [GO:0047039]; melanin biosynthetic process [GO:0042438]	dTDP-rhamnose biosynthetic process [GO:0019305]	melanin biosynthetic process [GO:0042438]			dTDP-4-dehydrorhamnose reductase activity [GO:0008831]; nucleotide binding [GO:0000166]	tetrahydroxynaphthalene reductase activity [GO:0047039]
d3sc6f__d2ohxb2__1		Metazoa	Firmicutes	Chordata	dTDP-4-dehydrorhamnose reductase activity [GO:0008831]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	dTDP-rhamnose biosynthetic process [GO:0019305]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	dTDP-4-dehydrorhamnose reductase activity [GO:0008831]; nucleotide binding [GO:0000166]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d3scfc1_d1b0na2__1			Actinobacteria	Firmicutes	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	protein dimerization activity [GO:0046983]; regulation of transcription, DNA-templated [GO:0006355]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	regulation of transcription, DNA-templated [GO:0006355]			dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]	protein dimerization activity [GO:0046983]
d3scgb1_d1zuga___1			Actinobacteria		dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	regulation of transcription, DNA-templated [GO:0006355]			dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]	DNA binding [GO:0003677]
d3scgb2_d3bu7b___1			Actinobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	gentisate 1,2-dioxygenase activity [GO:0047922]; metal ion binding [GO:0046872]; cellular aromatic compound metabolic process [GO:0006725]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]; phosphinothricin biosynthetic process [GO:1901766]; protein homotetramerization [GO:0051289]	cellular aromatic compound metabolic process [GO:0006725]			dioxygenase activity [GO:0051213]; DNA binding [GO:0003677]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [GO:0016717]	gentisate 1,2-dioxygenase activity [GO:0047922]; metal ion binding [GO:0046872]
d3scja__d4h82a___1	Metazoa	Metazoa	Chordata	Chordata	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3sclb__d3d0ib___1	Metazoa	Metazoa	Chordata	Chordata	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3scna__d1rp9a2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular space [GO:0005615]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d3scob__d2bvta2__1	Viridiplantae		Streptophyta	Actinobacteria	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]; substituted mannan metabolic process [GO:0006080]	extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	cellulase activity [GO:0008810]; mannan endo-1,4-beta-mannosidase activity [GO:0016985]; metal ion binding [GO:0046872]
d3scpa__d1xysb___1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]
d3scqa__d2v5ca2__1	Viridiplantae		Streptophyta	Firmicutes	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d3scqa__d4duwa3__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3scrb__d1lwhb2__1	Viridiplantae		Streptophyta	Thermotogae	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; 4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]; oligosaccharide catabolic process [GO:0009313]	carbohydrate metabolic process [GO:0005975]	oligosaccharide catabolic process [GO:0009313]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	4-alpha-glucanotransferase activity [GO:0004134]; alpha-amylase activity [GO:0004556]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]; metal ion binding [GO:0046872]
d3scrb__d5hnna1__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3scta__d1v3ia___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d3scua__d2wc4b___1	Viridiplantae		Streptophyta	Thermotogae	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3scub__d1xcxa2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular region [GO:0005576]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3scva__d1jf6b3__1	Viridiplantae		Streptophyta	Firmicutes	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	metal ion binding [GO:0046872]; neopullulanase activity [GO:0031216]
d3scwb__d3vd9b3__1	Viridiplantae		Streptophyta	Proteobacteria	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3sd9b__d4rl0b___1			Proteobacteria	Proteobacteria	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d3sdaa1_d1iaka2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]		peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]
d3sdaa2_d1u92a2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]			
d3sdaa2_d3uzvb1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3sdab__d1vgeh2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3sdab__d6azxb1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]			
d3sdac1_d5vagb1__1	Metazoa		Chordata	Negarnaviricota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d3sdad2_d4orgl1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]			
d3sdca1_d4l29w1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3sdcb__d3bd5b___1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]			
d3sdcc1_d1k4db2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3sdcd1_d2f53a1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	positive regulation of transcription by RNA polymerase II [GO:0045944]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytoplasm [GO:0005737]		
d3sdcd1_d4nqce2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3sdcd2_d5b6fc2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]			
d3sddc1_d1adql1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3sddd2_d3u0pb___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3sddd2_d5fk9b1__1	Metazoa		Chordata	Firmicutes	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]		metal ion binding [GO:0046872]; MHC class II protein binding [GO:0042289]; toxin activity [GO:0090729]
d3sdi2__d4quxq___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdib__d3hyen___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdif__d2f162___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdik__d3oeuv___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdim__d5l5jp___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdin__d1j2qk___1	Fungi		Ascomycota	Euryarchaeota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; proteasome core complex, alpha-subunit complex [GO:0019773]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	threonine-type endopeptidase activity [GO:0004298]
d3sdio__d4hrck___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdip__d5fhsw___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdiq__d5fgfv___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdiy__d3sdi2___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdiz__d4qwga___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdka__d5l5oc___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdkb__d4qwsx___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdkf__d3h4pm___1	Fungi		Ascomycota	Euryarchaeota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdkh__d5jhsz___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdko__d4qz3e___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdku__d5le5w___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdky__d4r67z___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3sdlb__d3m8ad___1	Metazoa		Chordata	Negarnaviricota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; RNA binding [GO:0003723]; suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	suppression by virus of host mRNA processing [GO:0039524]; suppression by virus of host PKR activity [GO:0039580]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	RNA binding [GO:0003723]
d3sdna__d1a0zb___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3sdwa__d2vvqa___1	Fungi		Ascomycota	Actinobacteria	isomerase activity [GO:0016853]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; ribose-5-phosphate isomerase activity [GO:0004751]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]		extracellular region [GO:0005576]	isomerase activity [GO:0016853]	ribose-5-phosphate isomerase activity [GO:0004751]
d3sdxa1_d1klua2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d3sdxb__d3uzqa2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3sdxb__d3v6of2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	basolateral plasma membrane [GO:0016323]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; leptin receptor activity [GO:0038021]; peptide hormone binding [GO:0017046]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; bone growth [GO:0098868]; cell surface receptor signaling pathway [GO:0007166]; cholesterol metabolic process [GO:0008203]; energy homeostasis [GO:0097009]; energy reserve metabolic process [GO:0006112]; glial cell proliferation [GO:0014009]; glucose homeostasis [GO:0042593]; glycogen metabolic process [GO:0005977]; leptin-mediated signaling pathway [GO:0033210]; multicellular organism development [GO:0007275]; negative regulation of autophagy [GO:0010507]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of hydrolase activity [GO:0051346]; phagocytosis [GO:0006909]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of bone remodeling [GO:0046850]; regulation of feeding behavior [GO:0060259]; response to leptin [GO:0044321]; sexual reproduction [GO:0019953]; T cell differentiation [GO:0030217]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	angiogenesis [GO:0001525]; bone growth [GO:0098868]; cell surface receptor signaling pathway [GO:0007166]; cholesterol metabolic process [GO:0008203]; energy homeostasis [GO:0097009]; energy reserve metabolic process [GO:0006112]; glial cell proliferation [GO:0014009]; glucose homeostasis [GO:0042593]; glycogen metabolic process [GO:0005977]; leptin-mediated signaling pathway [GO:0033210]; multicellular organism development [GO:0007275]; negative regulation of autophagy [GO:0010507]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of hydrolase activity [GO:0051346]; phagocytosis [GO:0006909]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of bone remodeling [GO:0046850]; regulation of feeding behavior [GO:0060259]; response to leptin [GO:0044321]; sexual reproduction [GO:0019953]; T cell differentiation [GO:0030217]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	basolateral plasma membrane [GO:0016323]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; leptin receptor activity [GO:0038021]; peptide hormone binding [GO:0017046]; transmembrane signaling receptor activity [GO:0004888]
d3sdxc1_d2ve6j2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3sdxd__d3ijsa2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3sdxe1_d2cdgb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3se1a__d1o9if___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	catalase activity [GO:0004096]; metal ion binding [GO:0046872]
d3se5d__d5ckla1__1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; protein adenylyltransferase activity [GO:0070733]; protein homodimerization activity [GO:0042803]; protein adenylylation [GO:0018117]; regulation of cell division [GO:0051302]	ATP binding [GO:0005524]; protein adenylyltransferase activity [GO:0070733]; protein homodimerization activity [GO:0042803]; protein adenylylation [GO:0018117]; regulation of cell division [GO:0051302]	protein adenylylation [GO:0018117]; regulation of cell division [GO:0051302]	protein adenylylation [GO:0018117]; regulation of cell division [GO:0051302]			ATP binding [GO:0005524]; protein adenylyltransferase activity [GO:0070733]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; protein adenylyltransferase activity [GO:0070733]; protein homodimerization activity [GO:0042803]
d3se8l1_d1otsc1__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3se8l2_d5b6fc1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d3se9l1_d5cckl1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d3seba1_d1l0xd1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	integral component of membrane [GO:0016021]			extracellular region [GO:0005576]	integral component of membrane [GO:0016021]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	
d3seca__d3llda___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3senc2_d1b4fb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; identical protein binding [GO:0042802]; signal transduction [GO:0007165]	axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; receptor complex [GO:0043235]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; nervous system development [GO:0007399]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	signal transduction [GO:0007165]	angiogenesis [GO:0001525]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; nervous system development [GO:0007399]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]	cytoplasm [GO:0005737]; membrane [GO:0016020]	axon [GO:0030424]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3sepb4_d2vr4b3__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-mannosidase activity [GO:0004567]
d3sepc1_d5dpna1__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3sepc3_d2c8nb2__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	lactose catabolic process [GO:0005990]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	beta-galactosidase complex [GO:0009341]	cytoplasm [GO:0005737]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-L-arabinofuranosidase activity [GO:0046556]
d3sepc5_d3i3bc5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3sepd3_d4do6a1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	lactose catabolic process [GO:0005990]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	beta-galactosidase complex [GO:0009341]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d3sera1_d4n6da1__1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	transmembrane transport [GO:0055085]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	
d3serc1_d1m5ea___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3sesa1_d1cb6a1__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; humoral immune response [GO:0006959]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing of cells of other organism [GO:0031640]; membrane disruption in other organism [GO:0051673]; negative regulation by host of viral process [GO:0044793]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ATPase activity [GO:0032780]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of membrane potential [GO:0045837]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; neutrophil degranulation [GO:0043312]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]; retina homeostasis [GO:0001895]; siderophore-dependent iron import into cell [GO:0033214]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; other organism cell membrane [GO:0044218]; phagocytic vesicle lumen [GO:0097013]; protein-containing complex [GO:0032991]; secretory granule [GO:0030141]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; DNA binding [GO:0003677]; heparin binding [GO:0008201]; iron ion binding [GO:0005506]; lipopolysaccharide binding [GO:0001530]; protein serine/threonine kinase activator activity [GO:0043539]; serine-type endopeptidase activity [GO:0004252]
d3sesa1_d2abha___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; phosphate ion binding [GO:0042301]; cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	cellular response to DNA damage stimulus [GO:0006974]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; regulation of phosphatase activity [GO:0010921]; response to radiation [GO:0009314]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	phosphate ion binding [GO:0042301]
d3sesc1_d1lahe___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	outer membrane-bounded periplasmic space [GO:0030288]; amino acid transport [GO:0006865]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	amino acid transport [GO:0006865]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	
d3sevc1_d2xxyc___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d3sexc1_d2i49a___1			Proteobacteria	Cyanobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	plasma membrane [GO:0005886]; ion transport [GO:0006811]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ion transport [GO:0006811]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	plasma membrane [GO:0005886]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	
d3sfca__d1qbub___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3sfda2_d1neka3__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d3sfdb2_d2b76n1__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d3sfeb2_d4kx6b2__1	Metazoa		Chordata	Proteobacteria	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane fumarate reductase complex [GO:0045284]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; fumarate metabolic process [GO:0006106]	mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; oxidation-reduction process [GO:0055114]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; fumarate metabolic process [GO:0006106]	mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; plasma membrane fumarate reductase complex [GO:0045284]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]	succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d3sfpb__d2yntc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d3sgae__d1p10a___1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d3sgae__d2gt7b___1			Actinobacteria		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular region [GO:0005576]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3sgdi1_d4wfhd2__1		Metazoa		Chordata		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]; identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]; cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]		cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; potassium channel complex [GO:0034705]		identical protein binding [GO:0042802]; mechanosensitived potassium channel activity [GO:0098782]; potassium channel activity [GO:0005267]; potassium ion leak channel activity [GO:0022841]; temperature-gated cation channel activity [GO:0097604]; voltage-gated ion channel activity [GO:0005244]
d3sgdi1_d5gs1m___1												
d3sgdi2_d4g7vl1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; ion channel activity [GO:0005216]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; phosphatidylinositol dephosphorylation [GO:0046856]		phosphatidylinositol dephosphorylation [GO:0046856]		integral component of membrane [GO:0016021]		ion channel activity [GO:0005216]; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity [GO:0016314]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d3sgdl2_d1h3ya1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3sgei1_d1ynta2__1				Firmicutes		cell wall [GO:0005618]; extracellular region [GO:0005576]; IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		cell wall [GO:0005618]; extracellular region [GO:0005576]		IgG binding [GO:0019864]; immunoglobulin binding [GO:0019865]
d3sgei2_d3dusc___1		Metazoa		Chordata								
d3sgja2_d4p49a1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		IgG binding [GO:0019864]	
d3sgjb2_d3dhma___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	IgG binding [GO:0019864]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3sgjb2_d4zdhb2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	IgG binding [GO:0019864]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3sgjc1_d1hzhh4__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	IgG binding [GO:0019864]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3sgjc1_d1nbqa2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell-cell junction [GO:0005911]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]; cadherin binding [GO:0045296]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618]; actomyosin structure organization [GO:0031032]; bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; establishment of endothelial intestinal barrier [GO:0090557]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to bicellular tight junction [GO:1902396]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of cytoskeleton organization [GO:0051493]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]; transforming growth factor beta receptor signaling pathway [GO:0007179]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	actomyosin structure organization [GO:0031032]; bicellular tight junction assembly [GO:0070830]; cell-cell adhesion [GO:0098609]; cellular response to mechanical stimulus [GO:0071260]; establishment of endothelial intestinal barrier [GO:0090557]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; intestinal absorption [GO:0050892]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; negative regulation of GTPase activity [GO:0034260]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of blood pressure [GO:0045777]; positive regulation of establishment of endothelial barrier [GO:1903142]; positive regulation of GTPase activity [GO:0043547]; positive regulation of platelet aggregation [GO:1901731]; positive regulation of Rho protein signal transduction [GO:0035025]; protein localization to bicellular tight junction [GO:1902396]; protein localization to plasma membrane [GO:0072659]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cell shape [GO:0008360]; regulation of cytokine production [GO:0001817]; regulation of cytoskeleton organization [GO:0051493]; regulation of membrane permeability [GO:0090559]; response to radiation [GO:0009314]; transforming growth factor beta receptor signaling pathway [GO:0007179]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	bicellular tight junction [GO:0005923]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; slit diaphragm [GO:0036057]; tight junction [GO:0070160]	IgG binding [GO:0019864]	cadherin binding [GO:0045296]; integrin binding [GO:0005178]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; virus receptor activity [GO:0001618]
d3sgka2_d4janl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	viral envelope [GO:0019031]; virion membrane [GO:0055036]	IgG binding [GO:0019864]	
d3sgkb1_d1kn4l2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	IgG binding [GO:0019864]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3sgkc2_d2iann2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	IgG binding [GO:0019864]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3sgyb__d3eeja1__1		Fungi	Firmicutes	Ascomycota	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; mRNA binding [GO:0003729]; NADP binding [GO:0050661]
d3sh1a1_d3wtnb1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3sh1c1_d3sq6b___1	Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	
d3sh1e1_d5bp0d1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3sh1i1_d3wtlb1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3sh1i1_d4xheh1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3sh4a__d3vkma1__1	Metazoa	Metazoa	Chordata	Chordata	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; plasma membrane [GO:0005886]; plasma membrane protein complex [GO:0098797]; amyloid-beta binding [GO:0001540]; calcium ion binding [GO:0005509]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; protein C-terminus binding [GO:0008022]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiovascular system development [GO:0072358]; cell differentiation [GO:0030154]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell death [GO:0060548]; receptor-mediated endocytosis [GO:0006898]; retinoid metabolic process [GO:0001523]; tissue development [GO:0009888]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiovascular system development [GO:0072358]; cell differentiation [GO:0030154]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell death [GO:0060548]; receptor-mediated endocytosis [GO:0006898]; retinoid metabolic process [GO:0001523]; tissue development [GO:0009888]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; plasma membrane [GO:0005886]; plasma membrane protein complex [GO:0098797]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	amyloid-beta binding [GO:0001540]; calcium ion binding [GO:0005509]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; protein C-terminus binding [GO:0008022]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]
d3sh6a__d2chpb___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3shdc__d1irya___1		Metazoa	Proteobacteria	Chordata	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTP diphosphatase activity [GO:0036219]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]; aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]		acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTPase activity [GO:0003924]; GTP diphosphatase activity [GO:0036219]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]
d3shdl__d1ow2a___1			Proteobacteria	Proteobacteria	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]		cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]		cytoplasm [GO:0005737]	nucleoside-triphosphatase activity [GO:0017111]; thiamine-pyrophosphatase activity [GO:0004787]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]
d3shha2_d4m0xa2__1				Actinobacteria		chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]						chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d3shia__d1ks7a___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]		extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3shim__d1zxva2__1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d3shj1__d5l5hb___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3shj2__d1iruz___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3shjd__d1z7qv1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3shjn__d5l5zc___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3shjp__d5bxnw___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3shjs__d5lf4r___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; secretory granule lumen [GO:0034774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3shjy__d5l5yo___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3shjz__d4qz6a___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3shmg__d3ng9d___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d3shmh__d3ra8a___1					viral capsid [GO:0019028]; structural molecule activity [GO:0005198]	viral capsid [GO:0019028]; structural molecule activity [GO:0005198]			viral capsid [GO:0019028]	viral capsid [GO:0019028]	structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d3shxa__d5ww9c___1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3si9c1_d1xxxa1__1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]
d3si9d1_d4e38c1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]		4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	4-hydroxy-2-oxoglutarate aldolase activity [GO:0008700]
d3si9d1_d4rxgd___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytoplasm [GO:0005737]; fructose 6-phosphate aldolase activity [GO:0097023]; fructose metabolic process [GO:0006000]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	fructose metabolic process [GO:0006000]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	fructose 6-phosphate aldolase activity [GO:0097023]
d3sika__d4wjg3___1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell wall [GO:0005618]; extracellular region [GO:0005576]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	metal ion binding [GO:0046872]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3sikb__d2o6pa1__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; peptidoglycan-based cell wall [GO:0009274]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; heme transport [GO:0015886]		heme transport [GO:0015886]	cell wall [GO:0005618]; extracellular region [GO:0005576]	extracellular region [GO:0005576]; peptidoglycan-based cell wall [GO:0009274]	metal ion binding [GO:0046872]	hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]
d3sila__d3ti4b___1			Proteobacteria	Negarnaviricota	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]; ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]; pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	ganglioside catabolic process [GO:0006689]; oligosaccharide catabolic process [GO:0009313]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; exo-alpha-sialidase activity [GO:0004308]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3siod1_d2byrg___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3sioe1_d3wtmd1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3siof1_d3guad1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3sioi1_d5tvhe1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3sioj1_d2w8fj___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3sisa1_d4haqb1__1		Metazoa		Arthropoda	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]			cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; metal ion binding [GO:0046872]
d3sitb__d3b01d___1				Thermotogae	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3siza__d5lnrd___1		Viridiplantae	Euryarchaeota	Streptophyta	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]; amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular amino acid metabolic process [GO:0006520]; chlorophyll metabolic process [GO:0015994]; hyperosmotic salinity response [GO:0042538]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; response to lipid hydroperoxide [GO:0006982]; response to non-ionic osmotic stress [GO:0010335]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]		cytosol [GO:0005829]; endomembrane system [GO:0012505]; plasma membrane [GO:0005886]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3sj3b__d4muzb1__1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3sj6a__d1j1sa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]			nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3sj8a__d1c5w.1__1		Metazoa		Chordata	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]	serine-type endopeptidase activity [GO:0004252]
d3sjia__d1p9ue___1					ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]		host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3sjna2_d1muca1__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; beta-ketoadipate pathway [GO:0042952]; cellular amino acid catabolic process [GO:0009063]	cellular amino acid catabolic process [GO:0009063]	beta-ketoadipate pathway [GO:0042952]; cellular amino acid catabolic process [GO:0009063]			metal ion binding [GO:0046872]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d3sjnb1_d2dw7o2__1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	cellular amino acid catabolic process [GO:0009063]	protein homooligomerization [GO:0051260]			metal ion binding [GO:0046872]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]
d3sjoe__d2alpa___1				Proteobacteria	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	serine-type endopeptidase activity [GO:0004252]
d3sjog__d2j92a1__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host chromatin organization [GO:0039525]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; regulation of translation [GO:0006417]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3sjoh__d2zwlh___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d3sjya2_d2zjrb1__1				Deinococcus-Thermus		cytosolic large ribosomal subunit [GO:0022625]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]		translation [GO:0006412]		cytosolic large ribosomal subunit [GO:0022625]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]
d3sjya2_d4pc1a2__1				Proteobacteria		cytoplasm [GO:0005737]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		translation elongation factor activity [GO:0003746]
d3sjza2_d4iw3b2__1			Crenarchaeota	Proteobacteria	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		cytosol [GO:0005829]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3sjza3_d5i4qc2__1			Crenarchaeota	Proteobacteria	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3sk0a1_d1k6ea___1			Actinobacteria	Proteobacteria	haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	periplasmic space [GO:0042597]; haloalkane dehalogenase activity [GO:0018786]; response to toxic substance [GO:0009636]	response to toxic substance [GO:0009636]	response to toxic substance [GO:0009636]		periplasmic space [GO:0042597]	haloalkane dehalogenase activity [GO:0018786]	haloalkane dehalogenase activity [GO:0018786]
d3sk3b1_d3mk6c2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	cytosol [GO:0005829]; nucleus [GO:0005634]; acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]; coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nucleus [GO:0005634]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]	acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]
d3sk4a__d2eyja___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3sk6a__d4s3sa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3skje__d4rydb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d3skjl1_d3qnyc1__1	Metazoa		Chordata		cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]		activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]		cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]		ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	
d3skjl2_d1hxmd1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	transmembrane signaling receptor activity [GO:0004888]
d3skjm2_d1a3lh1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3skjm2_d3ecbb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3skka__d4iu5a___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	arginine metabolic process [GO:0006525]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]
d3skkb__d5efga___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	angiogenesis [GO:0001525]; definitive hemopoiesis [GO:0060216]; hematopoietic progenitor cell differentiation [GO:0002244]; protein deacetylation [GO:0006476]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	potassium ion binding [GO:0030955]; protein deacetylase activity [GO:0033558]; tubulin deacetylase activity [GO:0042903]; zinc ion binding [GO:0008270]
d3skna1_d1ob1a1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3skna1_d4rfed1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]			
d3sknc1_d2ht4f2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]			
d3sknd1_d4fp8n1__1	Metazoa		Chordata	Negarnaviricota	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]
d3skne1_d5wlgb___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3sknf1_d1d5bb2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3skng1_d3uypa1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3sknh1_d1wvza___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; fibroblast growth factor binding [GO:0017134]; fibroblast growth factor-activated receptor activity [GO:0005007]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; cell-cell signaling [GO:0007267]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endochondral bone growth [GO:0003416]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; inner ear morphogenesis [GO:0042472]; in utero embryonic development [GO:0001701]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; mammary gland bud formation [GO:0060615]; MAPK cascade [GO:0000165]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; mesodermal cell differentiation [GO:0048333]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of transcription by RNA polymerase II [GO:0000122]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell division [GO:0051781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast differentiation [GO:0045667]; regulation of osteoblast proliferation [GO:0033688]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; skeletal system morphogenesis [GO:0048705]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847]; wound healing [GO:0042060]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell cortex [GO:0005938]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; excitatory synapse [GO:0060076]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; fibroblast growth factor-activated receptor activity [GO:0005007]; fibroblast growth factor binding [GO:0017134]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3sknh2_d5vzrl2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]			
d3skpa__d4yb7h1__1	Metazoa		Chordata	Proteobacteria	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	histidine biosynthetic process [GO:0000105]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d3sl3b__d2pw3b___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d3sl3c__d4jibd___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d3sl8a__d4yqhb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3slca2_d2fsja1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	ATP binding [GO:0005524]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]		cytoplasm [GO:0005737]		acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]	ATP binding [GO:0005524]
d3slcc2_d3h45o2__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	cytoplasm [GO:0005737]		acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d3slcd1_d4br5a1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adenosine-diphosphatase activity [GO:0043262]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	cytoplasm [GO:0005737]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]	adenosine-diphosphatase activity [GO:0043262]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]
d3slcd2_d3wxld2__1			Proteobacteria		cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]		acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; formate kinase activity [GO:0047900]; magnesium ion binding [GO:0000287]; propionate kinase activity [GO:0008980]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d3slpb__d1wteb___1				Proteobacteria	exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]						exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]	
d3sm4b1_d2aoqa___1				Proteobacteria	exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; DNA modification [GO:0006304]; mismatch repair [GO:0006298]		DNA modification [GO:0006304]; mismatch repair [GO:0006298]		cytoplasm [GO:0005737]	exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]
d3smbc__d4grrc___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d3smcb__d3mjzg___1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	
d3smcc__d5bscb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d3smsa2_d5aqlc1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nucleus [GO:0005634]; acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]; coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	acetyl-CoA binding [GO:1905502]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; protein homodimerization activity [GO:0042803]; vitamin binding [GO:0019842]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3sn2a2_d1c97a1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099]	citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]
d3sn2a2_d2pkpa___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099]	catalytic complex [GO:1902494]; aconitate hydratase activity [GO:0003994]; homoaconitate hydratase activity [GO:0004409]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; coenzyme B biosynthetic process [GO:0019298]	cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099]	coenzyme B biosynthetic process [GO:0019298]	cell [GO:0005623]; cytoplasm [GO:0005737]	catalytic complex [GO:1902494]	4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]	aconitate hydratase activity [GO:0003994]; homoaconitate hydratase activity [GO:0004409]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]
d3sn7a1_d5tzzb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d3sn8a__d4x2vb1__1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]		cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]
d3snda__d4isih___1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d3sndb__d1p9uf___1					cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3snfa__d2p6zb___1	Metazoa	Metazoa	Chordata	Chordata	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]				extracellular region [GO:0005576]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]
d3snga__d2fgna___1	Viridiplantae		Streptophyta	Firmicutes	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; DNA catabolic process [GO:0006308]	phosphatidylcholine phospholipase C activity [GO:0034480]; zinc ion binding [GO:0008270]; hemolysis in other organism [GO:0044179]	DNA catabolic process [GO:0006308]	hemolysis in other organism [GO:0044179]			endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	phosphatidylcholine phospholipase C activity [GO:0034480]; zinc ion binding [GO:0008270]
d3snpa2_d1amja1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]; cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099]	citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099]	cell [GO:0005623]; cytoplasm [GO:0005737]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]
d3snya__d1gcsa1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3snya__d4jgfa___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]		cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3snza__d1h4ax2__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]		cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3so0a__d2jdfa1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; lens fiber cell morphogenesis [GO:0070309]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; lens fiber cell morphogenesis [GO:0070309]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3so0b__d3hz2b___1			Firmicutes	Euryarchaeota	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3so0e__d1c01a___1		Viridiplantae	Firmicutes	Streptophyta	metal ion binding [GO:0046872]	extracellular region [GO:0005576]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]; negative regulation of growth [GO:0045926]		defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; killing of cells of other organism [GO:0031640]; negative regulation of growth [GO:0045926]		extracellular region [GO:0005576]	metal ion binding [GO:0046872]	
d3so0f__d1a45a1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3so1a__d2kfba2__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; structural constituent of eye lens [GO:0005212]; cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]		cellular response to reactive oxygen species [GO:0034614]; lens development in camera-type eye [GO:0002088]; lens fiber cell differentiation [GO:0070306]; visual perception [GO:0007601]		cytoplasm [GO:0005737]; nucleus [GO:0005634]	metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3so1b__d1ytqa2__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; structural molecule activity [GO:0005198]; lens development in camera-type eye [GO:0002088]; response to stimulus [GO:0050896]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; response to stimulus [GO:0050896]; visual perception [GO:0007601]			metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; structural molecule activity [GO:0005198]
d3so1c__d3hz2c___1			Firmicutes	Euryarchaeota	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3so1c__d4gcra2__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3so1e__d1bd7a___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]; camera-type eye development [GO:0043010]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		camera-type eye development [GO:0043010]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			metal ion binding [GO:0046872]	protein homodimerization activity [GO:0042803]; structural constituent of eye lens [GO:0005212]
d3so1f__d1elpa1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3so1h__d1zgta2__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]; lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]		lens development in camera-type eye [GO:0002088]; visual perception [GO:0007601]			metal ion binding [GO:0046872]	structural constituent of eye lens [GO:0005212]
d3so3b1_d1iama2__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	acute inflammatory response to antigenic stimulus [GO:0002438]; adhesion of symbiont to host [GO:0044406]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell aging [GO:0007569]; cellular response to alkaloid [GO:0071312]; cellular response to amyloid-beta [GO:1904646]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of Sertoli cell barrier [GO:0097368]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; ovarian follicle development [GO:0001541]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cellular extravasation [GO:0002693]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of vasoconstriction [GO:0045907]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of cell shape [GO:0008360]; regulation of immune response [GO:0050776]; regulation of leukocyte mediated cytotoxicity [GO:0001910]; regulation of ruffle assembly [GO:1900027]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to copper ion [GO:0046688]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to insulin [GO:0032868]; response to ionizing radiation [GO:0010212]; response to sulfur dioxide [GO:0010477]; sensory perception of sound [GO:0007605]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]; T cell antigen processing and presentation [GO:0002457]; T cell extravasation [GO:0072683]	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]
d3so3b2_d1n3na1__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3so3b2_d6bitl1__1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]	cornification [GO:0070268]; epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]	basolateral plasma membrane [GO:0016323]; extracellular space [GO:0005615]; extrinsic component of plasma membrane [GO:0019897]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]
d3so4a1_d3so4b2__1					cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d3so4a2_d1mxaa1__1				Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d3so4b3_d2hj2a3__1					cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]		one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]		cytosol [GO:0005829]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]	
d3so4c1_d4kttb1__1		Metazoa		Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d3so4c1_d5t8tb2__1				Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]
d3so4c3_d1mxba3__1				Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d3so4d1_d4le5b1__1					cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]		one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]		cytosol [GO:0005829]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]	
d3so4d2_d4kttd3__1		Metazoa		Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d3so4d3_d5ughc2__1		Metazoa		Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cellular response to leukemia inhibitory factor [GO:1990830]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]	cytosol [GO:0005829]; methionine adenosyltransferase complex [GO:0048269]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]
d3so9a__d5ozaa___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]
d3sobl1_d4m1gl1__1	Metazoa		Chordata		caveola [GO:0005901]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]; Wnt-Frizzled-LRP5/6 complex [GO:1990851]; apolipoprotein binding [GO:0034185]; coreceptor activity involved in canonical Wnt signaling pathway [GO:1904928]; coreceptor activity involved in Wnt signaling pathway [GO:0071936]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; kinase inhibitor activity [GO:0019210]; low-density lipoprotein particle receptor activity [GO:0005041]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; toxin transmembrane transporter activity [GO:0019534]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; anterior/posterior pattern specification [GO:0009952]; axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; gastrulation with mouth forming second [GO:0001702]; midbrain development [GO:0030901]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; roof of mouth development [GO:0060021]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]	anterior/posterior pattern specification [GO:0009952]; axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; gastrulation with mouth forming second [GO:0001702]; midbrain development [GO:0030901]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; roof of mouth development [GO:0060021]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]		caveola [GO:0005901]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202]; Wnt-Frizzled-LRP5/6 complex [GO:1990851]; Wnt signalosome [GO:1990909]	integral component of membrane [GO:0016021]	apolipoprotein binding [GO:0034185]; coreceptor activity involved in canonical Wnt signaling pathway [GO:1904928]; coreceptor activity involved in Wnt signaling pathway [GO:0071936]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; kinase inhibitor activity [GO:0019210]; low-density lipoprotein particle receptor activity [GO:0005041]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; toxin transmembrane transporter activity [GO:0019534]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]	metal ion binding [GO:0046872]
d3sody__d4mcmk___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d3sosa__d2g4ta___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	elastin catabolic process [GO:0060309]; exocrine pancreas development [GO:0031017]; inflammatory response [GO:0006954]; multicellular organism growth [GO:0035264]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas morphogenesis [GO:0061113]; positive regulation of angiogenesis [GO:0045766]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; proteolysis [GO:0006508]; regulation of cell differentiation [GO:0045595]; regulation of cell population proliferation [GO:0042127]; tissue remodeling [GO:0048771]; Wnt signaling pathway [GO:0016055]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3spka__d5p2ra___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]
d3spsa__d5t02a___1			Firmicutes	Proteobacteria	thiolester hydrolase activity [GO:0016790]	thiolester hydrolase activity [GO:0016790]					thiolester hydrolase activity [GO:0016790]	thiolester hydrolase activity [GO:0016790]
d3spsb__d1s9ci1__1		Metazoa	Firmicutes	Chordata	thiolester hydrolase activity [GO:0016790]	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]; alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]		alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]		cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	thiolester hydrolase activity [GO:0016790]	17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]
d3spsb__d5t07a___1			Firmicutes	Proteobacteria	thiolester hydrolase activity [GO:0016790]	plasma membrane [GO:0005886]; acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]; lipid metabolic process [GO:0006629]		lipid metabolic process [GO:0006629]		plasma membrane [GO:0005886]	thiolester hydrolase activity [GO:0016790]	acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]
d3spsf__d4ncpf___1			Firmicutes	Firmicutes	thiolester hydrolase activity [GO:0016790]	thiolester hydrolase activity [GO:0016790]					thiolester hydrolase activity [GO:0016790]	thiolester hydrolase activity [GO:0016790]
d3spsf__d5t06b___1			Firmicutes	Proteobacteria	thiolester hydrolase activity [GO:0016790]	plasma membrane [GO:0005886]; acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]; lipid metabolic process [GO:0006629]		lipid metabolic process [GO:0006629]		plasma membrane [GO:0005886]	thiolester hydrolase activity [GO:0016790]	acyl-CoA hydrolase activity [GO:0047617]; thiolester hydrolase activity [GO:0016790]
d3spub__d5n58b___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d3spuc1_d2yvdd___1			Proteobacteria		periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	
d3spud1_d5ni0e___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d3spza1_d2ex3i1__1					3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]
d3sq1a1_d2hhwa1__1				Firmicutes	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d3sq6i__d4xk9j1__1		Metazoa		Mollusca		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3sq9f__d4b5da___1		Metazoa		Annelida		integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]				integral component of membrane [GO:0016021]		extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]
d3sq9j__d5hbvb1__1		Metazoa		Chordata		extracellular region [GO:0005576]; host cell postsynaptic membrane [GO:0035792]; toxin activity [GO:0090729]				extracellular region [GO:0005576]; host cell postsynaptic membrane [GO:0035792]		toxin activity [GO:0090729]
d3sqcb2_d1s64f___1		Metazoa	Firmicutes	Chordata	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]; beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]; hopanoid biosynthetic process [GO:0019746]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]; CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]; negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	hopanoid biosynthetic process [GO:0019746]	negative regulation of apoptotic process [GO:0043066]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; response to cytokine [GO:0034097]; response to inorganic substance [GO:0010035]; response to organic cyclic compound [GO:0014070]	lipid droplet [GO:0005811]; plasma membrane [GO:0005886]	CAAX-protein geranylgeranyltransferase complex [GO:0005953]; cytoplasm [GO:0005737]; protein farnesyltransferase complex [GO:0005965]	beta-amyrin synthase activity [GO:0042300]; lanosterol synthase activity [GO:0000250]; lyase activity [GO:0016829]; squalene-hopene cyclase activity [GO:0051007]	CAAX-protein geranylgeranyltransferase activity [GO:0004662]; protein farnesyltransferase activity [GO:0004660]; protein geranylgeranyltransferase activity [GO:0004661]
d3sqee__d1dx5.1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d3sqgh1_d5g0rb1__1				Euryarchaeota	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]; methanogenesis [GO:0015948]	cytoplasm [GO:0005737]; coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; methanogenesis [GO:0015948]	methanogenesis [GO:0015948]	methanogenesis [GO:0015948]		cytoplasm [GO:0005737]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]; metal ion binding [GO:0046872]	coenzyme-B sulfoethylthiotransferase activity [GO:0050524]
d3sqja1_d1gnia3__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3sqjb1_d4j2va1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3sqjb2_d1h9za1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3sqka1_d3h86c___1				Euryarchaeota		cytoplasm [GO:0005737]; adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]				cytoplasm [GO:0005737]		adenylate kinase activity [GO:0004017]; ATP binding [GO:0005524]
d3sqol2_d4m5yl2__1	Metazoa		Chordata		cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor recycling [GO:0001920]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]		apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to insulin stimulus [GO:0032869]; cellular response to starvation [GO:0009267]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; kidney development [GO:0001822]; lipoprotein metabolic process [GO:0042157]; liver development [GO:0001889]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; lysosomal transport [GO:0007041]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of low-density lipoprotein particle receptor binding [GO:1905596]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of receptor recycling [GO:0001920]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; phospholipid metabolic process [GO:0006644]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of receptor internalization [GO:0002092]; post-translational protein modification [GO:0043687]; protein autoprocessing [GO:0016540]; regulation of neuron apoptotic process [GO:0043523]; regulation of signaling receptor activity [GO:0010469]; triglyceride metabolic process [GO:0006641]		cell surface [GO:0009986]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; endolysosome membrane [GO:0036020]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; PCSK9-AnxA2 complex [GO:1990667]; PCSK9-LDLR complex [GO:1990666]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]		apolipoprotein binding [GO:0034185]; apolipoprotein receptor binding [GO:0034190]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; protein self-association [GO:0043621]; receptor inhibitor activity [GO:0030547]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; sodium channel inhibitor activity [GO:0019871]; very-low-density lipoprotein particle binding [GO:0034189]; very-low-density lipoprotein particle receptor binding [GO:0070326]	
d3sr4a__d1suic___1	Metazoa	Viridiplantae	Chordata	Streptophyta	chromosome, telomeric region [GO:0000781]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; histone methyltransferase activity [GO:0042054]; histone methyltransferase activity (H3-K79 specific) [GO:0031151]; histone-lysine N-methyltransferase activity [GO:0018024]; transcription factor binding [GO:0008134]; chromatin silencing at telomere [GO:0006348]; DNA damage checkpoint [GO:0000077]; histone H3-K79 methylation [GO:0034729]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; regulation of transcription regulatory region DNA binding [GO:2000677]; telomere organization [GO:0032200]	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]; lignin biosynthetic process [GO:0009809]	chromatin silencing at telomere [GO:0006348]; DNA damage checkpoint [GO:0000077]; histone H3-K79 methylation [GO:0034729]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; regulation of transcription regulatory region DNA binding [GO:2000677]; telomere organization [GO:0032200]	lignin biosynthetic process [GO:0009809]	chromosome, telomeric region [GO:0000781]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		DNA binding [GO:0003677]; histone-lysine N-methyltransferase activity [GO:0018024]; histone methyltransferase activity [GO:0042054]; histone methyltransferase activity (H3-K79 specific) [GO:0031151]; transcription factor binding [GO:0008134]	caffeoyl-CoA O-methyltransferase activity [GO:0042409]; metal ion binding [GO:0046872]
d3sr5x__d2d0kb___1			Firmicutes	Proteobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; NADPH binding [GO:0070402]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to methotrexate [GO:0031427]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; dihydrofolic acid binding [GO:0051871]; folic acid binding [GO:0005542]; methotrexate binding [GO:0051870]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]; NADPH binding [GO:0070402]
d3sr6b1_d1diqb2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	FAD binding [GO:0071949]; oxidoreductase activity [GO:0016491]
d3sr6b2_d1t3qf1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	oxidoreductase activity [GO:0016491]	xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	oxidoreductase activity [GO:0016491]
d3sr6j1_d1krha3__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]; toluene catabolic process [GO:0042203]	xanthine catabolic process [GO:0009115]	toluene catabolic process [GO:0042203]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; ferredoxin-NAD+ reductase activity [GO:0008860]; metal ion binding [GO:0046872]
d3sr9a1_d4ri5b1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; spinal cord development [GO:0021510]; synapse organization [GO:0050808]; synaptic membrane adhesion [GO:0099560]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine phosphatase activity [GO:0004725]; sodium channel regulator activity [GO:0017080]; liver regeneration [GO:0097421]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of mitotic cell cycle [GO:0045930]; protein dephosphorylation [GO:0006470]; regulation of membrane depolarization during action potential [GO:0098902]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; spinal cord development [GO:0021510]; synapse organization [GO:0050808]; synaptic membrane adhesion [GO:0099560]	liver regeneration [GO:0097421]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of mitotic cell cycle [GO:0045930]; protein dephosphorylation [GO:0006470]; regulation of membrane depolarization during action potential [GO:0098902]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]	ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine phosphatase activity [GO:0004725]; sodium channel regulator activity [GO:0017080]
d3sr9a2_d2f6za___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; spinal cord development [GO:0021510]; synapse organization [GO:0050808]; synaptic membrane adhesion [GO:0099560]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; spinal cord development [GO:0021510]; synapse organization [GO:0050808]; synaptic membrane adhesion [GO:0099560]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3srpa__d1j1qa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endoplasmic reticulum [GO:0005783]; carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; killing of cells of other organism [GO:0031640]; negative regulation of translation [GO:0017148]	defense response to virus [GO:0051607]; negative regulation of translation [GO:0017148]	endoplasmic reticulum [GO:0005783]		carbohydrate binding [GO:0030246]; nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3srqx__d3sa2a1__1			Firmicutes	Firmicutes	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	folic acid-containing compound metabolic process [GO:0006760]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]			dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]
d3srxb__d2q42b2__1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	mitochondrion [GO:0005739]; hydroxyacylglutathione hydrolase activity [GO:0004416]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	periplasmic space [GO:0042597]	mitochondrion [GO:0005739]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	hydroxyacylglutathione hydrolase activity [GO:0004416]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]
d3ssbb__d3scib___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]		angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	extracellular region [GO:0005576]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3ssga__d1bzea___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3ssqb__d3cima1__1			Cyanobacteria	Cyanobacteria	identical protein binding [GO:0042802]						identical protein binding [GO:0042802]	
d3ssqc__d3i6pe___1			Cyanobacteria	Proteobacteria	identical protein binding [GO:0042802]	ethanolamine degradation polyhedral organelle [GO:0031471]; structural molecule activity [GO:0005198]; ethanolamine catabolic process [GO:0046336]		ethanolamine catabolic process [GO:0046336]		ethanolamine degradation polyhedral organelle [GO:0031471]	identical protein binding [GO:0042802]	structural molecule activity [GO:0005198]
d3ssqd__d5djbd___1			Cyanobacteria	Proteobacteria	identical protein binding [GO:0042802]						identical protein binding [GO:0042802]	
d3ssra__d4ppda___1			Cyanobacteria	Proteobacteria	identical protein binding [GO:0042802]						identical protein binding [GO:0042802]	
d3sssa1_d3cimc1__1			Cyanobacteria	Cyanobacteria	identical protein binding [GO:0042802]						identical protein binding [GO:0042802]	
d3sssb1_d4qied___1			Cyanobacteria	Proteobacteria	identical protein binding [GO:0042802]						identical protein binding [GO:0042802]	
d3ssxr__d1trrg___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]
d3st5a__d5p6wa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3st8a2_d1mr7a___1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]; adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	transferase activity, transferring acyl groups [GO:0016746]; response to antibiotic [GO:0046677]	adhesion of symbiont to host cell [GO:0044650]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; entry of bacterium into host cell [GO:0035635]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; uridylyltransferase activity [GO:0070569]	transferase activity, transferring acyl groups [GO:0016746]
d3stai__d2d3ta4__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation [GO:0006635]	cytoplasm [GO:0005737]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d3stav__d1ey3b___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; fatty acid beta-oxidation [GO:0006635]		fatty acid beta-oxidation [GO:0006635]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]
d3stav__d1yg8z___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]		proteasomal protein catabolic process [GO:0010498]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to radiation [GO:0009314]; response to temperature stimulus [GO:0009266]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; endopeptidase Clp complex [GO:0009368]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3stdb__d3t8nf___1	Fungi		Ascomycota	Proteobacteria	endosome [GO:0005768]; metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]; melanin biosynthetic process [GO:0042438]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	melanin biosynthetic process [GO:0042438]	steroid metabolic process [GO:0008202]	endosome [GO:0005768]		metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]	steroid delta-isomerase activity [GO:0004769]
d3stdc__d2z77b___1	Fungi		Ascomycota	Actinobacteria	endosome [GO:0005768]; metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]; melanin biosynthetic process [GO:0042438]	isomerase activity [GO:0016853]; protein homodimerization activity [GO:0042803]; sterol binding [GO:0032934]	melanin biosynthetic process [GO:0042438]		endosome [GO:0005768]		metal ion binding [GO:0046872]; scytalone dehydratase activity [GO:0030411]	isomerase activity [GO:0016853]; protein homodimerization activity [GO:0042803]; sterol binding [GO:0032934]
d3stja2_d4nmpa___1		Metazoa	Proteobacteria	Chordata	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]	ion channel binding [GO:0044325]
d3stjh2_d4uu5a1__1		Metazoa	Proteobacteria	Chordata	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	apical plasma membrane [GO:0016324]; axon [GO:0030424]; bicellular tight junction [GO:0005923]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; lateral loop [GO:0043219]; myelin sheath adaxonal region [GO:0035749]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schmidt-Lanterman incisure [GO:0043220]; ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; bicellular tight junction assembly [GO:0070830]; establishment of epithelial cell polarity [GO:0090162]; morphogenesis of an epithelial sheet [GO:0002011]; myelin assembly [GO:0032288]; peripheral nervous system myelin maintenance [GO:0032287]; protein localization to myelin sheath abaxonal region [GO:0035750]; protein localization to plasma membrane [GO:0072659]	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	bicellular tight junction assembly [GO:0070830]; establishment of epithelial cell polarity [GO:0090162]; morphogenesis of an epithelial sheet [GO:0002011]; myelin assembly [GO:0032288]; peripheral nervous system myelin maintenance [GO:0032287]; protein localization to myelin sheath abaxonal region [GO:0035750]; protein localization to plasma membrane [GO:0072659]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]	apical plasma membrane [GO:0016324]; axon [GO:0030424]; bicellular tight junction [GO:0005923]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; lateral loop [GO:0043219]; myelin sheath adaxonal region [GO:0035749]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; Schmidt-Lanterman incisure [GO:0043220]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]
d3stji2_d4jogb___1		Metazoa	Proteobacteria	Chordata	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]; ion channel binding [GO:0044325]; apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle membrane [GO:0030660]; Golgi membrane [GO:0000139]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; trans-Golgi network transport vesicle [GO:0030140]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]	ion channel binding [GO:0044325]
d3stjj2_d2opga1__1		Metazoa	Proteobacteria	Chordata	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]; protein C-terminus binding [GO:0008022]; cell adhesion [GO:0007155]; viral process [GO:0016032]	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cell adhesion [GO:0007155]; viral process [GO:0016032]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]	apical plasma membrane [GO:0016324]; apicolateral plasma membrane [GO:0016327]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; Schmidt-Lanterman incisure [GO:0043220]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]	protein C-terminus binding [GO:0008022]
d3stjk2_d2zlea1__1			Proteobacteria	Proteobacteria	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	integral component of external side of plasma membrane [GO:0071575]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3stmx1_d2a2gb___1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]
d3stta__d6emia___1	Viridiplantae	Metazoa	Streptophyta	Chordata		blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]		choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]		blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]		acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]
d3sttb__d2ajdd2__1	Viridiplantae	Metazoa	Streptophyta	Chordata		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]		dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3sttb__d5gmrb___1	Viridiplantae		Streptophyta			hydrolase activity [GO:0016787]						hydrolase activity [GO:0016787]
d3stua__d4x6ua1__1	Viridiplantae		Streptophyta	Firmicutes		metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]						metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d3stub__d5akxa2__1	Viridiplantae	Metazoa	Streptophyta	Chordata		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3stva__d1f6wa___1	Viridiplantae	Metazoa	Streptophyta	Chordata		cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; presynapse [GO:0098793]; synapse [GO:0045202]; acetylesterase activity [GO:0008126]; catalytic activity [GO:0003824]; heparin binding [GO:0008201]; hydrolase activity [GO:0016787]; neurexin family protein binding [GO:0042043]; signaling receptor activity [GO:0038023]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; cholesterol catabolic process [GO:0006707]; fatty acid catabolic process [GO:0009062]; intestinal cholesterol absorption [GO:0030299]; intestinal lipid catabolic process [GO:0044258]; lipid digestion [GO:0044241]; lipid metabolic process [GO:0006629]; modulation of chemical synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; pancreatic juice secretion [GO:0030157]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein esterification [GO:0018350]; synaptic vesicle endocytosis [GO:0048488]		cholesterol catabolic process [GO:0006707]; fatty acid catabolic process [GO:0009062]; intestinal cholesterol absorption [GO:0030299]; intestinal lipid catabolic process [GO:0044258]; lipid digestion [GO:0044241]; lipid metabolic process [GO:0006629]; modulation of chemical synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; pancreatic juice secretion [GO:0030157]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein esterification [GO:0018350]; synaptic vesicle endocytosis [GO:0048488]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; presynapse [GO:0098793]; synapse [GO:0045202]		acetylesterase activity [GO:0008126]; catalytic activity [GO:0003824]; heparin binding [GO:0008201]; hydrolase activity [GO:0016787]; neurexin family protein binding [GO:0042043]; signaling receptor activity [GO:0038023]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d3stva__d2oqva2__1	Viridiplantae	Metazoa	Streptophyta	Chordata		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3stwb__d3d2ck___1	Viridiplantae		Streptophyta	Firmicutes		extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]		lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d3stwb__d4fhza1__1	Viridiplantae		Streptophyta	Proteobacteria		hydrolase activity [GO:0016787]						hydrolase activity [GO:0016787]
d3stxa__d2bgnc2__1	Viridiplantae	Metazoa	Streptophyta	Chordata		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]		dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3styb__d1brob___1	Viridiplantae		Streptophyta	Actinobacteria		peroxidase activity [GO:0004601]; antibiotic biosynthetic process [GO:0017000]		antibiotic biosynthetic process [GO:0017000]				peroxidase activity [GO:0004601]
d3stza1_d1m05b___1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	voltage-gated potassium channel complex [GO:0008076]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3stza2_d2c7ua1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	voltage-gated potassium channel complex [GO:0008076]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3stzb1_d1aqdk1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]		antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; CD8-positive, alpha-beta T cell activation [GO:0036037]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; protein ubiquitination [GO:0016567]; regulation of immune response [GO:0050776]; T cell mediated cytotoxicity [GO:0001913]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	voltage-gated potassium channel complex [GO:0008076]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; TAP binding [GO:0046977]
d3stzb2_d3t3mf1__1		Metazoa	Actinobacteria	Chordata	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	voltage-gated potassium channel complex [GO:0008076]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3su0a1_d4ausa1__1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	
d3su1a1_d1c1ta___1		Metazoa		Chordata	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	digestion [GO:0007586]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3su2a1_d1dxwa1__1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	serine-type peptidase activity [GO:0008236]; transformation of host cell by virus [GO:0019087]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	transformation of host cell by virus [GO:0019087]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	serine-type peptidase activity [GO:0008236]
d3su3a1_d3sufa___1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3su4a__d4agka___1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3su5a1_d1rtl.1__1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3sudb__d1op8c___1		Metazoa		Chordata	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; immunological synapse [GO:0001772]; nucleus [GO:0005634]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; immune response [GO:0006955]; negative regulation of DNA binding [GO:0043392]; negative regulation of endodeoxyribonuclease activity [GO:0032078]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to bacterium [GO:0009617]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; immune response [GO:0006955]; negative regulation of DNA binding [GO:0043392]; negative regulation of endodeoxyribonuclease activity [GO:0032078]; negative regulation of oxidoreductase activity [GO:0051354]; positive regulation of apoptotic process [GO:0043065]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to bacterium [GO:0009617]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; immunological synapse [GO:0001772]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]
d3sufb__d5eqra1__1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; transformation of host cell by virus [GO:0019087]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	transformation of host cell by virus [GO:0019087]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d3sufc__d1svpa___1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; membrane fusion [GO:0061025]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; icosahedral viral capsid, spike [GO:0098029]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; ubiquitin-like protein ligase binding [GO:0044389]
d3sv6a1_d1cu1b1__1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; identical protein binding [GO:0042802]; ion channel activity [GO:0005216]; protease binding [GO:0002020]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; SH3 domain binding [GO:0017124]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3sv9a1_d2fomb1__1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3svfa1_d5fh6a___1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; mitotic cell cycle [GO:0000278]; negative regulation of cell population proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; transcription elongation from RNA polymerase II promoter [GO:0006368]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nuclear chromosome [GO:0000228]; nucleoplasm [GO:0005654]; RSC-type complex [GO:0016586]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]
d3svhb__d5pcqa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleus [GO:0005634]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d3svla__d2bmva___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; xenobiotic metabolic process [GO:0006805]	FMN binding [GO:0010181]; oxidation-reduction process [GO:0055114]	xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]		FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]
d3svlb__d1xyva___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]		FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3svlb__d3qe2b1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	xenobiotic metabolic process [GO:0006805]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	FMN binding [GO:0010181]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d3sw5e__d3q46a___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]; inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]; phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	phosphate-containing compound metabolic process [GO:0006796]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]	inorganic diphosphatase activity [GO:0004427]; magnesium ion binding [GO:0000287]
d3swla1_d5dalb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3swnd__d1lojc1__1	Fungi		Ascomycota	Euryarchaeota	Lsm2-8 complex [GO:0120115]; nucleolus [GO:0005730]; nucleus [GO:0005634]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; maturation of SSU-rRNA [GO:0030490]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; telomerase holoenzyme complex assembly [GO:1905323]; tRNA processing [GO:0008033]	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	maturation of SSU-rRNA [GO:0030490]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; telomerase holoenzyme complex assembly [GO:1905323]; tRNA processing [GO:0008033]	mRNA splicing, via spliceosome [GO:0000398]	Lsm2-8 complex [GO:0120115]; nucleolus [GO:0005730]; nucleus [GO:0005634]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]	small nucleolar ribonucleoprotein complex [GO:0005732]	poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]	
d3swnq__d1mgqe___1	Fungi		Ascomycota	Euryarchaeota	Lsm2-8 complex [GO:0120115]; nucleolus [GO:0005730]; nucleus [GO:0005634]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; maturation of SSU-rRNA [GO:0030490]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; telomerase holoenzyme complex assembly [GO:1905323]; tRNA processing [GO:0008033]	small nucleolar ribonucleoprotein complex [GO:0005732]; mRNA splicing, via spliceosome [GO:0000398]	maturation of SSU-rRNA [GO:0030490]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; telomerase holoenzyme complex assembly [GO:1905323]; tRNA processing [GO:0008033]	mRNA splicing, via spliceosome [GO:0000398]	Lsm2-8 complex [GO:0120115]; nucleolus [GO:0005730]; nucleus [GO:0005634]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]	small nucleolar ribonucleoprotein complex [GO:0005732]	poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]	
d3swns__d4m78k___1	Fungi	Fungi	Ascomycota	Ascomycota	Lsm2-8 complex [GO:0120115]; nucleolus [GO:0005730]; nucleus [GO:0005634]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]; poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]; maturation of SSU-rRNA [GO:0030490]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; telomerase holoenzyme complex assembly [GO:1905323]; tRNA processing [GO:0008033]	Lsm1-7-Pat1 complex [GO:1990726]; nucleolus [GO:0005730]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]	maturation of SSU-rRNA [GO:0030490]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; telomerase holoenzyme complex assembly [GO:1905323]; tRNA processing [GO:0008033]	maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]	Lsm2-8 complex [GO:0120115]; nucleolus [GO:0005730]; nucleus [GO:0005634]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; telomerase holoenzyme complex [GO:0005697]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]	Lsm1-7-Pat1 complex [GO:1990726]; nucleolus [GO:0005730]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]	poly(U) RNA binding [GO:0008266]; RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3swoc2_d1is2b1__1		Metazoa	Actinobacteria	Chordata	flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA hydrolase activity [GO:0044466]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; palmitoyl-CoA oxidase activity [GO:0016401]; protein homodimerization activity [GO:0042803]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693]; very long-chain fatty acid metabolic process [GO:0000038]		fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693]; very long-chain fatty acid metabolic process [GO:0000038]		peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA hydrolase activity [GO:0044466]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	acyl-CoA oxidase activity [GO:0003997]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; flavin adenine dinucleotide binding [GO:0050660]; palmitoyl-CoA oxidase activity [GO:0016401]; protein homodimerization activity [GO:0042803]
d3swod2_d1jqia1__1		Metazoa	Actinobacteria	Chordata	flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA hydrolase activity [GO:0044466]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]; butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; protein homotetramerization [GO:0051289]; response to glucocorticoid [GO:0051384]; response to starvation [GO:0042594]		butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; protein homotetramerization [GO:0051289]; response to glucocorticoid [GO:0051384]; response to starvation [GO:0042594]		mitochondrial matrix [GO:0005759]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; glutaryl-CoA hydrolase activity [GO:0044466]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	acyl-CoA dehydrogenase activity [GO:0003995]; butyryl-CoA dehydrogenase activity [GO:0004085]; fatty-acyl-CoA binding [GO:0000062]; flavin adenine dinucleotide binding [GO:0050660]
d3swxb__d1on3f1__1			Actinobacteria	Actinobacteria	isomerase activity [GO:0016853]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		acetyl-CoA carboxylase complex [GO:0009317]	isomerase activity [GO:0016853]	acetyl-CoA carboxylase activity [GO:0003989]; methylmalonyl-CoA carboxytransferase activity [GO:0047154]
d3swxc__d3r0oa___1			Actinobacteria	Actinobacteria	isomerase activity [GO:0016853]	catalytic activity [GO:0003824]					isomerase activity [GO:0016853]	catalytic activity [GO:0003824]
d3sx2f__d5adha2__1		Metazoa	Actinobacteria	Chordata	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d3sx4a2_d1orwb2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3sx4b1_d4ffwb1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3sxtf__d1mdah___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3sxwa1_d4ynia___1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cysteine metabolic process [GO:0006534]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d3sy0a1_d3cvhl2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3sy0a2_d1mimh1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3sy0b2_d4v1db___1		Metazoa		Arthropoda		extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]		defense response [GO:0006952]		extracellular region [GO:0005576]		sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]
d3sy5b__d3lv5b___1			Euryarchaeota	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3sz6a__d3qzpa1__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]			cell wall [GO:0005618]; extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3sz6b__d3qzod1__1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]			cell wall [GO:0005618]; extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3sz9b__d2bjkb___1	Metazoa		Chordata	Deinococcus-Thermus	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3sz9c__d4cbbh___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glycine betaine biosynthetic process from choline [GO:0019285]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]
d3sz9g__d4i3th___1	Metazoa		Chordata	Proteobacteria	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3sz9h__d1o04h___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3sz9h__d2j6lg___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]; cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cellular aldehyde metabolic process [GO:0006081]; choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]; lysine catabolic process [GO:0006554]; sensory perception of sound [GO:0007605]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; L-aminoadipate-semialdehyde dehydrogenase activity [GO:0004043]
d3szab__d4ohta___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3szba__d2onng___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3szbb__d3n82f___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3szia__d4ggza___1			Proteobacteria	Proteobacteria	biotin binding [GO:0009374]	biotin binding [GO:0009374]					biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3szil__d2fhnx___1		Metazoa	Proteobacteria	Chordata	biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]				extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3szja1_d4bj8c___1		Metazoa	Proteobacteria	Chordata	biotin binding [GO:0009374]	biotin binding [GO:0009374]					biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3szka__d3g53b___1	Metazoa	Metazoa	Chordata	Mollusca	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3szkd__d2qrwd___1	Metazoa		Chordata	Actinobacteria	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxygen transport [GO:0015671]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; thioredoxin peroxidase activity [GO:0008379]
d3t00a__d3t02a___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]	metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]					metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]	metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]
d3t04a__d1a81g1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein homooligomerization [GO:0051260]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; cell surface receptor signaling pathway [GO:0007166]; cerebellum development [GO:0021549]; dendrite development [GO:0016358]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; negative thymic T cell selection [GO:0045060]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of T cell anergy [GO:0002669]; positive regulation of T cell proliferation [GO:0042102]; positive thymic T cell selection [GO:0045059]; protein-containing complex assembly [GO:0065003]; protein homooligomerization [GO:0051260]; regulation of apoptotic process [GO:0042981]; regulation of immune response [GO:0050776]; response to nutrient [GO:0007584]; signal complex assembly [GO:0007172]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]	alpha-beta T cell receptor complex [GO:0042105]; cell body [GO:0044297]; cell-cell junction [GO:0005911]; dendritic spine [GO:0043197]; external side of plasma membrane [GO:0009897]; immunological synapse [GO:0001772]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]	protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; receptor signaling complex adaptor activity [GO:0030159]; SH3 domain binding [GO:0017124]; T cell receptor binding [GO:0042608]; transmembrane signaling receptor activity [GO:0004888]
d3t04a__d3eaca___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; positive regulation of MAP kinase activity [GO:0043406]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]	cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase A catalytic subunit binding [GO:0034236]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]
d3t08a4_d3vd5c2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t08a5_d1lf6b2__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; polysaccharide metabolic process [GO:0005976]	lactose catabolic process [GO:0005990]	polysaccharide metabolic process [GO:0005976]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]
d3t08b3_d1isxb2__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	endo-1,4-beta-xylanase activity [GO:0031176]
d3t08b3_d3ahvb___1		Viridiplantae	Proteobacteria	Streptophyta	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d3t08b4_d3vd5b2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t08d2_d2vzva5__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3t08d2_d3iaqa4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t09a4_d1hn1c1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t09b3_d2pwfc1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3t09b4_d1px4d1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t09b4_d2vzva2__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3t09c5_d1tqta2__1		Metazoa	Proteobacteria	Arthropoda	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d3t09d1_d2x05b1__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3t0aa1_d3cqoc1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	metal ion binding [GO:0046872]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]
d3t0aa5_d1bglg4__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3t0ab2_d3vdbc4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t0ab3_d4bcec___1			Proteobacteria	Deinococcus-Thermus	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3t0ac5_d1jyxd4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t0ad2_d1jz7b2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t0ad3_d1v0na___1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d3t0ad5_d1hn1d4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t0ad5_d3l4ua1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	lactose catabolic process [GO:0005990]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	beta-galactosidase complex [GO:0009341]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]
d3t0ba1_d4omce2__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	lactose catabolic process [GO:0005990]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	beta-galactosidase complex [GO:0009341]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d3t0ba2_d1jz4b2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t0bb1_d1uyyb___1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3t0bb2_d2vzob4__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3t0bb3_d2vx4a___1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3t0bb3_d2x42a1__1			Proteobacteria	Thermotogae	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3t0bb4_d1f4hd1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t0bc3_d4puda___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	endo-1,4-beta-xylanase activity [GO:0031176]
d3t0bc3_d5brpb1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; alpha,alpha-phosphotrehalase activity [GO:0008788]; metal ion binding [GO:0046872]; trehalose catabolic process [GO:0005993]	lactose catabolic process [GO:0005990]	trehalose catabolic process [GO:0005993]	beta-galactosidase complex [GO:0009341]	cytoplasm [GO:0005737]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha,alpha-phosphotrehalase activity [GO:0008788]; metal ion binding [GO:0046872]
d3t0bc5_d3iaqc5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t0bd3_d1r87a___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	lactose catabolic process [GO:0005990]	xylan catabolic process [GO:0045493]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	endo-1,4-beta-xylanase activity [GO:0031176]
d3t0bd4_d3t08c2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t0da1_d3jqwc1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]; collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]	lactose catabolic process [GO:0005990]	collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]
d3t0da3_d4bf7a1__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; cell wall organization [GO:0071555]; pectin catabolic process [GO:0045490]	lactose catabolic process [GO:0005990]	cell wall organization [GO:0071555]; pectin catabolic process [GO:0045490]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]
d3t0da5_d5m0xa1__1			Proteobacteria	Thermotogae	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	alpha-galactosidase activity [GO:0004557]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; carbohydrate metabolic process [GO:0005975]; glycoside catabolic process [GO:0016139]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoside catabolic process [GO:0016139]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-galactosidase activity [GO:0004557]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]
d3t0dc2_d3k4da2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	lactose catabolic process [GO:0005990]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	beta-galactosidase complex [GO:0009341]	cytosol [GO:0005829]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d3t0dc3_d3tv8a1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	lactose catabolic process [GO:0005990]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	beta-galactosidase complex [GO:0009341]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d3t0dc5_d1ns7a1__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d3t0dd1_d1lnsa2__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; dipeptidyl-peptidase activity [GO:0008239]; serine-type peptidase activity [GO:0008236]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	cytoplasm [GO:0005737]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	dipeptidyl-peptidase activity [GO:0008239]; serine-type peptidase activity [GO:0008236]
d3t0dd3_d2cerb___1			Proteobacteria	Crenarchaeota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]
d3t0dd3_d3scnb___1		Viridiplantae	Proteobacteria	Streptophyta	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d3t0ra__d1tdva___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; toxin activity [GO:0090729]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d3t0wa__d4p2cj1__1				Proteobacteria		extracellular region [GO:0005576]; hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]		hemolysis by symbiont of host erythrocytes [GO:0019836]; pathogenesis [GO:0009405]		extracellular region [GO:0005576]		
d3t0wb__d1w0wa1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3t0xb__d1bd2b___1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3t11b__d5p0ha___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3t1da__d5m6ja___1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; negative regulation of coagulation [GO:0050819]; nitric oxide homeostasis [GO:0033484]; platelet aggregation [GO:0070527]; positive regulation of blood vessel diameter [GO:0097755]; response to histamine [GO:0034776]; vasodilation [GO:0042311]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	negative regulation of coagulation [GO:0050819]; nitric oxide homeostasis [GO:0033484]; platelet aggregation [GO:0070527]; positive regulation of blood vessel diameter [GO:0097755]; response to histamine [GO:0034776]; vasodilation [GO:0042311]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	extracellular region [GO:0005576]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d3t1fb__d1yymq2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d3t1fb__d5mx3b1__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3t1ka__d3g7ea___1	Metazoa		Chordata	Proteobacteria	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; DNA-dependent ATPase activity [GO:0008094]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; transcription, DNA-templated [GO:0006351]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [GO:0009330]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA negative supercoiling activity [GO:0034335]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d3t1ma__d3b7md___1	Metazoa		Chordata	Bacteroidetes	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	polysaccharide catabolic process [GO:0000272]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]		carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]	cellulase activity [GO:0008810]
d3t25a__d4mpwa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3t2he__d4gerb___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3t2he__d5lhdd2__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]		angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	aminopeptidase activity [GO:0004177]; metalloaminopeptidase activity [GO:0070006]; metallopeptidase activity [GO:0008237]; peptide binding [GO:0042277]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3t2je__d4hx3g1__1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	serine-type endopeptidase inhibitor activity [GO:0004867]			extracellular region [GO:0005576]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	serine-type endopeptidase inhibitor activity [GO:0004867]
d3t2nl1_d2gjjb2__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]; basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]		basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]		apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]		calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]	
d3t2nl1_d5jopl2__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]; basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]		basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]		apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]		calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]	
d3t2nl2_d5u7oe1__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]; basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]	structural molecule activity [GO:0005198]
d3t2nm1_d5wk3v1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]; basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; CCR4 chemokine receptor binding [GO:0031729]; chemokine activity [GO:0008009]; signaling receptor binding [GO:0005102]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; multicellular organism development [GO:0007275]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil chemotaxis [GO:0030593]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; multicellular organism development [GO:0007275]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil chemotaxis [GO:0030593]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]	apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]	calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]	CCR4 chemokine receptor binding [GO:0031729]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; signaling receptor binding [GO:0005102]
d3t2nm2_d4dzba1__1	Metazoa		Chordata		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]; basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]		basement membrane disassembly [GO:0034769]; cochlea morphogenesis [GO:0090103]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; pilomotor reflex [GO:0097195]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of plasminogen activation [GO:0010756]; positive regulation of thyroid hormone generation [GO:2000611]; potassium ion transmembrane transport [GO:0071805]; proteolysis [GO:0006508]; regulation of cell shape [GO:0008360]; response to thyroid hormone [GO:0097066]		apical plasma membrane [GO:0016324]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]		calcium-activated potassium channel activity [GO:0015269]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]; serine-type peptidase activity [GO:0008236]	
d3t2oa4_d2vzua5__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3t2oa5_d3lppb1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	beta-galactosidase complex [GO:0009341]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]
d3t2ob3_d2pwda1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3t2ob5_d4duvb5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t2oc1_d5c7ga___1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]; coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	lactose catabolic process [GO:0005990]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	beta-galactosidase complex [GO:0009341]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d3t2oc4_d2vr4b1__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-mannosidase activity [GO:0004567]
d3t2oc5_d1jyvd4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t2od2_d3t2pc4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t2od4_d1bgmn1__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3t2pa4_d3vdac2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t2pa5_d3t0ba5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t2pb2_d2vota3__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-mannosidase activity [GO:0004567]
d3t2pd5_d1bglf4__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3t2qa3_d1j11d2__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3t2qc1_d2j1rb___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]
d3t2qd2_d2vzsa2__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3t2qd2_d3t08b4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3t2qd3_d5h4ra___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3t2va__d2cb3c___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; peptidoglycan receptor activity [GO:0016019]; zinc ion binding [GO:0008270]; antimicrobial humoral response [GO:0019730]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of natural killer cell differentiation involved in immune response [GO:0032827]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of innate immune response [GO:0045089]; positive regulation of phagocytosis [GO:0050766]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	antimicrobial humoral response [GO:0019730]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; determination of adult lifespan [GO:0008340]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of natural killer cell differentiation involved in immune response [GO:0032827]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of innate immune response [GO:0045089]; positive regulation of phagocytosis [GO:0050766]	extracellular region [GO:0005576]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; peptidoglycan receptor activity [GO:0016019]; zinc ion binding [GO:0008270]
d3t2xa__d4bbob___1			Proteobacteria	Proteobacteria	biotin binding [GO:0009374]	biotin binding [GO:0009374]					biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3t3aa__d4kmb21__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]		complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d3t3ca__d3d20b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3t3ja__d2fug71__1	Metazoa		Chordata	Deinococcus-Thermus	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]		cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]	quinone binding [GO:0048038]
d3t3ka__d4ec2a___1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	cell [GO:0005623]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron chaperone activity [GO:0034986]; cellular iron ion homeostasis [GO:0006879]; glutathione metabolic process [GO:0006749]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; mitochondrion organization [GO:0007005]; response to iron(II) ion [GO:0010040]; response to oxidative stress [GO:0006979]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	cellular iron ion homeostasis [GO:0006879]; glutathione metabolic process [GO:0006749]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; mitochondrion organization [GO:0007005]; response to iron(II) ion [GO:0010040]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron chaperone activity [GO:0034986]
d3t3ka__d4lk8b___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	ferric iron binding [GO:0008199]; iron-sulfur cluster assembly [GO:0016226]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	iron-sulfur cluster assembly [GO:0016226]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]	ferric iron binding [GO:0008199]
d3t3la__d3iam7___1	Metazoa		Chordata	Deinococcus-Thermus	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]		cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]	quinone binding [GO:0048038]
d3t3ma__d4um9a1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	cell junction [GO:0030054]; centrosome [GO:0005813]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alphav-beta6 complex [GO:0034685]; integrin complex [GO:0008305]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; regulation of transforming growth factor beta activation [GO:1901388]; transforming growth factor-beta secretion [GO:0038044]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; extracellular matrix organization [GO:0030198]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; regulation of transforming growth factor beta activation [GO:1901388]; transforming growth factor-beta secretion [GO:0038044]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	cell junction [GO:0030054]; centrosome [GO:0005813]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alphav-beta6 complex [GO:0034685]; integrin complex [GO:0008305]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	integrin binding [GO:0005178]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]
d3t3ml1_d2ianp1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3t3ml1_d3wihm1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]
d3t3ml2_d4larl___1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	
d3t3pf1_d2esve2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3t3pf2_d2r0zl1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3t3pf2_d2xzal2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	
d3t3pl1_d3fjtb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3t3pl1_d3mlsl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	
d3t3pl2_d2i60q1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	structural molecule activity [GO:0005198]
d3t3qa__d2q6ng1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	endoplasmic reticulum membrane [GO:0005789]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	endoplasmic reticulum membrane [GO:0005789]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3t3qc__d4icta___1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]; oxidation-reduction process [GO:0055114]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	carbon monoxide binding [GO:0070025]; cyclase activity [GO:0009975]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated [GO:0046996]
d3t3qd__d2bmhb___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d3t3sc__d2qbla___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3t3sf__d3p6oa___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	cytoplasm [GO:0005737]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3t3xa__d2fugq1__1	Metazoa		Chordata	Deinococcus-Thermus	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]		cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]	quinone binding [GO:0048038]
d3t3xa__d3s5fb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]
d3t3xb__d3iasz___1	Metazoa		Chordata	Deinococcus-Thermus	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	plasma membrane [GO:0005886]; quinone binding [GO:0048038]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]		cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]	quinone binding [GO:0048038]
d3t3xb__d3s5fa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]; adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; iron-sulfur cluster assembly [GO:0016226]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; L-cysteine desulfurase complex [GO:1990221]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]	2 iron, 2 sulfur cluster binding [GO:0051537]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; iron chaperone activity [GO:0034986]
d3t3ya__d4bhia2__1		Metazoa	Proteobacteria	Chordata	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]; carnitine biosynthetic process [GO:0045329]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	carnitine biosynthetic process [GO:0045329]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]	gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]
d3t4ea1_d3phjb1__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; NADP binding [GO:0050661]; quinate 3-dehydrogenase (NAD+) activity [GO:0030266]; quinate 3-dehydrogenase (NADP+) activity [GO:0052733]; shikimate 3-dehydrogenase (NAD+) activity [GO:0052734]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]	cytosol [GO:0005829]	NADP binding [GO:0050661]; quinate 3-dehydrogenase (NAD+) activity [GO:0030266]; quinate 3-dehydrogenase (NADP+) activity [GO:0052733]; shikimate 3-dehydrogenase (NAD+) activity [GO:0052734]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d3t4ea2_d2hk9c2__1			Proteobacteria	Aquificae	cytosol [GO:0005829]; NADP binding [GO:0050661]; quinate 3-dehydrogenase (NAD+) activity [GO:0030266]; quinate 3-dehydrogenase (NADP+) activity [GO:0052733]; shikimate 3-dehydrogenase (NAD+) activity [GO:0052734]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]	cytosol [GO:0005829]	NADP binding [GO:0050661]; quinate 3-dehydrogenase (NAD+) activity [GO:0030266]; quinate 3-dehydrogenase (NADP+) activity [GO:0052733]; shikimate 3-dehydrogenase (NAD+) activity [GO:0052734]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d3t4mb1_d5aflc___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3t4mc1_d5afmb___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3t4me1_d4afhc___1	Metazoa	Metazoa	Mollusca	Annelida	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]
d3t4mg1_d5afnd___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3t4ua__d3heae___1			Proteobacteria	Proteobacteria	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]					arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]
d3t4uc__d1hkhb___1			Proteobacteria	Actinobacteria	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	peroxidase activity [GO:0004601]					arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	peroxidase activity [GO:0004601]
d3t4yb2_d4kkld1__1				Proteobacteria		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]		chloride transport [GO:0006821]; nitrate transport [GO:0015706]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d3t50a1_d1jnua___1		Viridiplantae	Proteobacteria	Streptophyta	ATP binding [GO:0005524]; photoreceptor activity [GO:0009881]; protein histidine kinase activity [GO:0004673]; pathogenesis [GO:0009405]; protein-chromophore linkage [GO:0018298]; response to stimulus [GO:0050896]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	pathogenesis [GO:0009405]; protein-chromophore linkage [GO:0018298]; response to stimulus [GO:0050896]	detection of visible light [GO:0009584]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; photoreceptor activity [GO:0009881]; protein histidine kinase activity [GO:0004673]	ATP binding [GO:0005524]; protein kinase activity [GO:0004672]
d3t52b__d4xiia___1		Metazoa	Proteobacteria	Chordata	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]		choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]		blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]
d3t52c__d4wy8c1__1		Fungi	Proteobacteria	Mucoromycota	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	methyl indole-3-acetate esterase activity [GO:0080030]					arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	methyl indole-3-acetate esterase activity [GO:0080030]
d3t52d__d4k2ac1__1			Proteobacteria	Proteobacteria	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	haloalkane dehalogenase activity [GO:0018786]					arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	haloalkane dehalogenase activity [GO:0018786]
d3t52f__d3fyum___1			Proteobacteria	Firmicutes	arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	acetylesterase activity [GO:0008126]					arylesterase activity [GO:0004064]; peroxidase activity [GO:0004601]	acetylesterase activity [GO:0008126]
d3t5gb__d5e6zd1__1	Metazoa		Chordata	Proteobacteria	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	response to stimulus [GO:0050896]; visual perception [GO:0007601]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]	cytosol [GO:0005829]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3t5id__d5aa7a___1	Metazoa		Chordata	Actinobacteria	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]	response to stimulus [GO:0050896]; visual perception [GO:0007601]	carbohydrate metabolic process [GO:0005975]	cilium [GO:0005929]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]	extracellular region [GO:0005576]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; GTPase inhibitor activity [GO:0005095]; Rab GTPase binding [GO:0017137]	carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d3t63n__d2pcdd___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]
d3t65a1_d5j13b2__1		Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-7 receptor binding [GO:0005139]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine (C-C motif) ligand 1 production [GO:0071654]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of granulocyte colony-stimulating factor production [GO:0071657]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of interleukin-5 secretion [GO:2000664]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mast cell activation [GO:0033005]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]		antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response to fungus [GO:0050832]; defense response to Gram-negative bacterium [GO:0050829]; interleukin-7-mediated signaling pathway [GO:0038111]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine (C-C motif) ligand 1 production [GO:0071654]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of granulocyte colony-stimulating factor production [GO:0071657]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of interleukin-5 secretion [GO:2000664]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mast cell activation [GO:0033005]; positive regulation of receptor signaling pathway via STAT [GO:1904894]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; interleukin-7 receptor binding [GO:0005139]
d3t67b__d1dmhb___1			Proteobacteria	Proteobacteria	ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]; 3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	catechol 1,2-dioxygenase activity [GO:0018576]; ferric iron binding [GO:0008199]; beta-ketoadipate pathway [GO:0042952]; catechol-containing compound catabolic process [GO:0019614]	3,4-dihydroxybenzoate catabolic process [GO:0019619]; beta-ketoadipate pathway [GO:0042952]	beta-ketoadipate pathway [GO:0042952]; catechol-containing compound catabolic process [GO:0019614]			ferric iron binding [GO:0008199]; protocatechuate 3,4-dioxygenase activity [GO:0018578]	catechol 1,2-dioxygenase activity [GO:0018576]; ferric iron binding [GO:0008199]
d3t6ca2_d3q45e2__1			Proteobacteria	Bacteroidetes	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	peptide metabolic process [GO:0006518]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d3t6dc__d3wmmc___1			Proteobacteria	Proteobacteria	plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	integral component of membrane [GO:0016021]; plasma membrane light-harvesting complex [GO:0030077]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; photosynthesis, light reaction [GO:0019684]	photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	photosynthesis, light reaction [GO:0019684]	plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	integral component of membrane [GO:0016021]; plasma membrane light-harvesting complex [GO:0030077]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]
d3t6ia__d5ah8a___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3t6ua__d1l92a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3t6va1_d3t6zb3__1	Fungi	Fungi	Basidiomycota	Basidiomycota	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]					copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3t6va3_d3fq2a___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3t6vb3_d1mg2c___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3t6vc2_d2bwia2__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3t6vc2_d4yseb2__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3t6wa1_d2ft7a___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3t6wa1_d3t71b2__1	Fungi	Fungi	Basidiomycota	Basidiomycota	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]					copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3t6wa3_d2xx1c1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]			copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3t6wb3_d3n2jb___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3t6wc3_d4knsf1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]			copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3t6xa2_d1kcwa6__1	Fungi	Metazoa	Basidiomycota	Chordata	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]		cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]		blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d3t6xa3_d2ppca1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3t6xa3_d4n2ea1__1	Fungi	Metazoa	Basidiomycota	Chordata	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; chromatin-mediated maintenance of transcription [GO:0048096]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]		cellular response to leukemia inhibitory factor [GO:1990830]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin organization [GO:0006325]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]
d3t6xb1_d2xx0b1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]			copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3t6xb1_d4a68a3__1	Fungi		Basidiomycota	Firmicutes	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3t6xb2_d4jkna___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3t6xc1_d5n8ia2__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3t6zb1_d3pxla1__1	Fungi	Fungi	Basidiomycota	Basidiomycota	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]					copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3t6zb1_d4ko7a___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3t6zb3_d1mg2k___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3t6zc3_d3h4ha1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3t71a1_d2ghzb___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3t71a3_d2xwze1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]			copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3t71b2_d1wa2x1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]			copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3t71c1_d4n25a1__1	Fungi	Metazoa	Basidiomycota	Chordata	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein homodimerization activity [GO:0042803]; protein-arginine deiminase activity [GO:0004668]; cellular response to leukemia inhibitory factor [GO:1990830]; chromatin organization [GO:0006325]; chromatin-mediated maintenance of transcription [GO:0048096]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]		cellular response to leukemia inhibitory factor [GO:1990830]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin organization [GO:0006325]; histone citrullination [GO:0036414]; histone H3-R26 citrullination [GO:0036413]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of lymphocyte chemotaxis [GO:1901624]; neutrophil degranulation [GO:0043312]; protein citrullination [GO:0018101]; regulation of chromatin disassembly [GO:0010848]; substantia nigra development [GO:0021762]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	calcium ion binding [GO:0005509]; estrogen receptor binding [GO:0030331]; protein-arginine deiminase activity [GO:0004668]; protein homodimerization activity [GO:0042803]
d3t73a__d1jizb1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3t77a1_d4dz8a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular space [GO:0005615]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	metal ion binding [GO:0046872]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3t77b2_d2yd6a1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; cell adhesion molecule binding [GO:0050839]; protein tyrosine phosphatase activity [GO:0004725]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]	immune response [GO:0006955]; immunoglobulin production [GO:0002377]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse assembly [GO:0051965]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; regulation of presynapse assembly [GO:1905606]; synaptic membrane adhesion [GO:0099560]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]; trans-synaptic signaling by trans-synaptic complex [GO:0099545]	extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	cell adhesion molecule binding [GO:0050839]; protein tyrosine phosphatase activity [GO:0004725]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine phosphatase activity [GO:0005001]
d3t77b2_d3i6kf1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metal ion binding [GO:0046872]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	immune response [GO:0006955]; immunoglobulin production [GO:0002377]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3t7oa1_d1tw1a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]; glycogenin glucosyltransferase activity [GO:0008466]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity [GO:0102751]; glycogen biosynthetic process [GO:0005978]; neutrophil degranulation [GO:0043312]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	glycogen biosynthetic process [GO:0005978]; neutrophil degranulation [GO:0043312]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	glycogenin glucosyltransferase activity [GO:0008466]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity [GO:0102751]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d3t7pa__d2zgaa___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3t7qa__d3jw2a___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3t7ya__d3bzl.1__1			Chlamydiae	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]; protein secretion [GO:0009306]	protein secretion [GO:0009306]	protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]		dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]
d3t7yb__d2jlha___1			Chlamydiae	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; pathogenesis [GO:0009405]; protein secretion [GO:0009306]	protein secretion [GO:0009306]	pathogenesis [GO:0009405]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		
d3t7yb__d3bzra1__1			Chlamydiae	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]; protein secretion [GO:0009306]	protein secretion [GO:0009306]	protein secretion [GO:0009306]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]		dioxygenase activity [GO:0051213]; isomerase activity [GO:0016853]
d3t80a1_d1iv4e___1			Proteobacteria	Deinococcus-Thermus	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]			2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [GO:0008685]; metal ion binding [GO:0046872]
d3t82a__d4xixe___1	Metazoa	Viridiplantae	Chordata	Chlorophyta	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3t83a__d4yhah___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3t88b__d3ktkm___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; bicarbonate binding [GO:0071890]; menaquinone biosynthetic process [GO:0009234]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]; ATP-dependent peptidase activity [GO:0004176]; ATPase binding [GO:0051117]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	menaquinone biosynthetic process [GO:0009234]	protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; endopeptidase Clp complex [GO:0009368]	1,4-dihydroxy-2-naphthoyl-CoA synthase activity [GO:0008935]; bicarbonate binding [GO:0071890]	ATPase binding [GO:0051117]; ATP-dependent peptidase activity [GO:0004176]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]
d3t8da__d1yp1a___1			Firmicutes		extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]				extracellular region [GO:0005576]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	
d3t8ga__d2tmne___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3t8ga__d3kecb1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]		bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]
d3t8ha__d1japa___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]		collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3t8na__d5m18b1__1			Proteobacteria	Firmicutes	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; transferase activity, transferring glycosyl groups [GO:0016757]; response to antibiotic [GO:0046677]	steroid metabolic process [GO:0008202]	response to antibiotic [GO:0046677]		integral component of membrane [GO:0016021]	steroid delta-isomerase activity [GO:0004769]	penicillin binding [GO:0008658]; transferase activity, transferring glycosyl groups [GO:0016757]
d3t8nb__d5bxqa___1		Metazoa	Proteobacteria	Chordata	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	steroid metabolic process [GO:0008202]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]		cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	steroid delta-isomerase activity [GO:0004769]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]
d3t8ud__d4nhfe___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; protein secretion by the type IV secretion system [GO:0030255]	steroid metabolic process [GO:0008202]	protein secretion by the type IV secretion system [GO:0030255]		integral component of membrane [GO:0016021]	steroid delta-isomerase activity [GO:0004769]	metal ion binding [GO:0046872]
d3t8xa2_d5wkie2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3t8xb__d2bsud4__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3t8xb__d5vigb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3t8xc2_d4jhal1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3t8xd__d4hbqb2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; integrin binding involved in cell-matrix adhesion [GO:0098640]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte migration [GO:2000403]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	integrin binding involved in cell-matrix adhesion [GO:0098640]
d3t8ya__d3gwga___1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; phosphorelay response regulator activity [GO:0000156]; protein-glutamate methylesterase activity [GO:0008984]; protein-glutamine glutaminase activity [GO:0050568]; chemotaxis [GO:0006935]; protein deamination [GO:0018277]; protein demethylation [GO:0006482]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	chemotaxis [GO:0006935]; protein deamination [GO:0018277]; protein demethylation [GO:0006482]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	phosphorelay response regulator activity [GO:0000156]; protein-glutamate methylesterase activity [GO:0008984]; protein-glutamine glutaminase activity [GO:0050568]	metal ion binding [GO:0046872]
d3t90a__d1b87a___1	Viridiplantae		Streptophyta	Firmicutes	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]; N-acetylglucosamine metabolic process [GO:0006044]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	N-acetyltransferase activity [GO:0008080]	N-acetylglucosamine metabolic process [GO:0006044]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]		glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]	N-acetyltransferase activity [GO:0008080]
d3t93d__d2ghbb___1	Metazoa		Chordata	Thermotogae	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	proteasome core complex, alpha-subunit complex [GO:0019773]; carbohydrate transmembrane transporter activity [GO:0015144]; endopeptidase activity [GO:0004175]; ubiquitin-dependent protein catabolic process [GO:0006511]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ubiquitin-dependent protein catabolic process [GO:0006511]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	proteasome core complex, alpha-subunit complex [GO:0019773]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbohydrate transmembrane transporter activity [GO:0015144]; endopeptidase activity [GO:0004175]
d3t94a__d4ynba1__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d3t94b__d5mx6b___1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	purine nucleoside metabolic process [GO:0042278]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]	purine-nucleoside phosphorylase activity [GO:0004731]
d3t94c__d3qpbn___1			Crenarchaeota	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]	uridine phosphorylase activity [GO:0004850]
d3t94d__d4ffsa1__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	L-methionine salvage from methylthioadenosine [GO:0019509]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]
d3t96f__d3fvka___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3t9hf__d5b3ya___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3t9ma__d4rl2a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d3t9ua__d2al4d___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3t9ua__d2xd3a___1	Metazoa		Chordata	Firmicutes	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	plasma membrane [GO:0005886]; carbohydrate transmembrane transporter activity [GO:0015144]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	plasma membrane [GO:0005886]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbohydrate transmembrane transporter activity [GO:0015144]
d3t9ub__d2o7ug___1	Metazoa	Metazoa	Chordata	Chordata	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d3t9va__d1ytvb___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3ta1d1_d3ta2b___1			Euryarchaeota	Euryarchaeota	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]	regulation of nitrogen utilization [GO:0006808]	regulation of nitrogen utilization [GO:0006808]			ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]
d3ta2a__d4yb7h2__1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	regulation of nitrogen utilization [GO:0006808]	histidine biosynthetic process [GO:0000105]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d3ta2b__d4y65a___1			Euryarchaeota	Proteobacteria	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; metal ion binding [GO:0046872]; protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	regulation of nitrogen utilization [GO:0006808]	protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]	copper ion binding [GO:0005507]; metal ion binding [GO:0046872]
d3ta2c__d2xunh___1			Euryarchaeota		ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]		regulation of nitrogen utilization [GO:0006808]				ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]	
d3ta3d1_d1fvea2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ta3d2_d3c6la2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ta3d2_d4hwbl2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; interleukin-13 receptor complex [GO:0005898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-2 binding [GO:0019976]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; interleukin-13 receptor complex [GO:0005898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-2 binding [GO:0019976]
d3ta8a__d4dasl___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3taec1_d3t3fa1__1				Deinococcus-Thermus	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; nucleoside binding [GO:0001882]
d3tagc1_d1xi1b1__1					3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]; DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]			3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exonuclease activity [GO:0004527]; metal ion binding [GO:0046872]; nucleoside binding [GO:0001882]; nucleotide binding [GO:0000166]
d3taka__d2qjii___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]; aromatic amino acid family biosynthetic process [GO:0009073]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	aromatic amino acid family biosynthetic process [GO:0009073]	cytoplasm [GO:0005737]		4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	fructose-bisphosphate aldolase activity [GO:0004332]; hydro-lyase activity [GO:0016836]; transferase activity, transferring aldehyde or ketonic groups [GO:0016744]
d3taqa1_d3nh2e___1				Proteobacteria		cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]; 3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]		DNA replication proofreading [GO:0045004]; tRNA 3'-end processing [GO:0042780]		cytosol [GO:0005829]; DNA polymerase III, core complex [GO:0044776]		3'-5' exonuclease activity [GO:0008408]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d3tatd__d1amqa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aromatic-amino-acid:2-oxoglutarate aminotransferase activity [GO:0008793]; identical protein binding [GO:0042802]; L-leucine:2-oxoglutarate aminotransferase activity [GO:0050048]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; aspartate biosynthetic process [GO:0006532]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]; leucine biosynthetic process [GO:0009098]; tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate [GO:0019292]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	aspartate biosynthetic process [GO:0006532]; leucine biosynthetic process [GO:0009098]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]; tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate [GO:0019292]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	aromatic-amino-acid:2-oxoglutarate aminotransferase activity [GO:0008793]; identical protein binding [GO:0042802]; L-leucine:2-oxoglutarate aminotransferase activity [GO:0050048]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d3tate__d1oxoa___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; aromatic-amino-acid:2-oxoglutarate aminotransferase activity [GO:0008793]; identical protein binding [GO:0042802]; L-leucine:2-oxoglutarate aminotransferase activity [GO:0050048]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; aspartate biosynthetic process [GO:0006532]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]; leucine biosynthetic process [GO:0009098]; tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate [GO:0019292]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; 2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	aspartate biosynthetic process [GO:0006532]; leucine biosynthetic process [GO:0009098]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]; tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate [GO:0019292]	2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	aromatic-amino-acid:2-oxoglutarate aminotransferase activity [GO:0008793]; identical protein binding [GO:0042802]; L-leucine:2-oxoglutarate aminotransferase activity [GO:0050048]; L-phenylalanine:2-oxoglutarate aminotransferase activity [GO:0080130]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]
d3tayb1_d2p3ia___1					host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; sialic acid binding [GO:0033691]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; receptor-mediated virion attachment to host cell [GO:0046813]; viral entry into host cell [GO:0046718]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; receptor-mediated virion attachment to host cell [GO:0046813]; viral entry into host cell [GO:0046718]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]		sialic acid binding [GO:0033691]
d3tb6b__d5dkva1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]				cytoplasm [GO:0005737]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	
d3tblc1_d1ok7b2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3tble__d1rfaa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; mitogen-activated protein kinase kinase binding [GO:0031434]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; activation of adenylate cyclase activity [GO:0007190]; activation of MAPKK activity [GO:0000186]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; death-inducing signaling complex assembly [GO:0071550]; face development [GO:0060324]; heart development [GO:0007507]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; intermediate filament cytoskeleton organization [GO:0045104]; ion transmembrane transport [GO:0034220]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of protein complex assembly [GO:0031333]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet activation [GO:0030168]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell differentiation [GO:0045595]; regulation of cell motility [GO:2000145]; regulation of Rho protein signal transduction [GO:0035023]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of adenylate cyclase activity [GO:0007190]; activation of MAPKK activity [GO:0000186]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; death-inducing signaling complex assembly [GO:0071550]; face development [GO:0060324]; heart development [GO:0007507]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; intermediate filament cytoskeleton organization [GO:0045104]; ion transmembrane transport [GO:0034220]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of protein complex assembly [GO:0031333]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet activation [GO:0030168]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell differentiation [GO:0045595]; regulation of cell motility [GO:2000145]; regulation of Rho protein signal transduction [GO:0035023]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; pseudopodium [GO:0031143]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; MAP kinase kinase kinase activity [GO:0004709]; metal ion binding [GO:0046872]; mitogen-activated protein kinase kinase binding [GO:0031434]; protein heterodimerization activity [GO:0046982]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d3tble__d2ma9b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]	ubiquitin protein ligase binding [GO:0031625]
d3tc6a1_d3lhvb___1			Crenarchaeota	Euryarchaeota	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3tc7a1_d3rlua___1			Crenarchaeota	Euryarchaeota	indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	tryptophan biosynthetic process [GO:0000162]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3tcfa__d3t96d___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3tcfb__d1b7ua2__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	extracellular space [GO:0005615]; specific granule [GO:0042581]; metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; bone morphogenesis [GO:0060349]; innate immune response in mucosa [GO:0002227]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; negative regulation of apoptotic process [GO:0043066]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of osteoclast development [GO:2001205]; negative regulation of single-species biofilm formation in or on host organism [GO:1900229]; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production [GO:2000308]; ossification [GO:0001503]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of chondrocyte proliferation [GO:1902732]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; regulation of cytokine production [GO:0001817]; regulation of tumor necrosis factor production [GO:0032680]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	extracellular space [GO:0005615]; specific granule [GO:0042581]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]	metal ion binding [GO:0046872]; serine-type peptidase activity [GO:0008236]
d3tcfc__d3qyta2__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]; actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	actin filament organization [GO:0007015]; activation of JUN kinase activity [GO:0007257]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; ERK1 and ERK2 cascade [GO:0070371]; iron ion homeostasis [GO:0055072]; membrane organization [GO:0061024]; osteoclast differentiation [GO:0030316]; platelet degranulation [GO:0002576]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell motility [GO:2000147]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of transcription, DNA-templated [GO:0045893]; post-translational protein modification [GO:0043687]; regulation of iron ion transport [GO:0034756]; regulation of protein stability [GO:0031647]; response to bacterium [GO:0009617]; retina homeostasis [GO:0001895]; SMAD protein signal transduction [GO:0060395]; transferrin transport [GO:0033572]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	apical plasma membrane [GO:0016324]; basal part of cell [GO:0045178]; basal plasma membrane [GO:0009925]; blood microparticle [GO:0072562]; cell [GO:0005623]; cell surface [GO:0009986]; clathrin-coated pit [GO:0005905]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasmic vesicle [GO:0031410]; early endosome [GO:0005769]; endocytic vesicle [GO:0030139]; endoplasmic reticulum lumen [GO:0005788]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; extrinsic component of external side of plasma membrane [GO:0031232]; HFE-transferrin receptor complex [GO:1990712]; late endosome [GO:0005770]; perinuclear region of cytoplasm [GO:0048471]; recycling endosome [GO:0055037]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]	ferric iron binding [GO:0008199]; ferric iron transmembrane transporter activity [GO:0015091]; ferrous iron binding [GO:0008198]; iron chaperone activity [GO:0034986]; transferrin receptor binding [GO:1990459]
d3tcfd__d1zlqa1__1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]	heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]
d3tcfd__d5mm3b___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3tcfe__d2xx9c___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3tcfe__d4n4ub___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	transmembrane transport [GO:0055085]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]		oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]	
d3tcfg__d3ppqb___1			Proteobacteria	Firmicutes	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; amino acid transport [GO:0006865]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	amino acid transport [GO:0006865]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]	transmembrane transporter activity [GO:0022857]
d3tcgc__d1tt1a___1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d3tcgc__d3sexa1__1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3tcgd__d4h5gb___1			Proteobacteria	Firmicutes	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	membrane [GO:0016020]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]	ligand-gated ion channel activity [GO:0015276]
d3tcge__d4ykkb___1		Metazoa	Proteobacteria	Ctenophora (ctenophores)	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ionotropic glutamate receptor activity [GO:0004970]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]	ionotropic glutamate receptor activity [GO:0004970]
d3tclb1_d4odxl___1		Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; monomeric IgA immunoglobulin complex [GO:0071748]; pentameric IgM immunoglobulin complex [GO:0071756]; plasma membrane [GO:0005886]; secretory IgA immunoglobulin complex [GO:0071751]; antigen binding [GO:0003823]; antibacterial humoral response [GO:0019731]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		antibacterial humoral response [GO:0019731]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; glomerular filtration [GO:0003094]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; monomeric IgA immunoglobulin complex [GO:0071748]; pentameric IgM immunoglobulin complex [GO:0071756]; plasma membrane [GO:0005886]; secretory IgA immunoglobulin complex [GO:0071751]		antigen binding [GO:0003823]
d3tclb2_d1igyd2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3tclb2_d2bjml___1		Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		
d3tcll2_d2i9lg1__1						integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]		integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		
d3tcob__d1g7oa2__1			Crenarchaeota	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; glutathione oxidoreductase activity [GO:0097573]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; glutathione oxidoreductase activity [GO:0097573]
d3tcob__d4zbda1__1		Fungi	Crenarchaeota	Basidiomycota	cell [GO:0005623]; cytoplasm [GO:0005737]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]; cytoplasm [GO:0005737]		oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	
d3tcra__d2nqra3__1			Actinobacteria	Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]		molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; molybdopterin adenylyltransferase activity [GO:0061598]; molybdopterin molybdotransferase activity [GO:0061599]
d3tcya__d2xsnb___1		Metazoa	Proteobacteria	Chordata	iron ion binding [GO:0005506]; phenylalanine 4-monooxygenase activity [GO:0004505]; L-phenylalanine catabolic process [GO:0006559]	axon [GO:0030424]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome membrane [GO:0033162]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; smooth endoplasmic reticulum [GO:0005790]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]; amino acid binding [GO:0016597]; dopamine binding [GO:0035240]; enzyme binding [GO:0019899]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; oxygen binding [GO:0019825]; protein domain specific binding [GO:0019904]; tetrahydrobiopterin binding [GO:0034617]; tyrosine 3-monooxygenase activity [GO:0004511]; aminergic neurotransmitter loading into synaptic vesicle [GO:0015842]; anatomical structure morphogenesis [GO:0009653]; animal organ morphogenesis [GO:0009887]; catecholamine biosynthetic process [GO:0042423]; cellular response to alkaloid [GO:0071312]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to manganese ion [GO:0071287]; cellular response to nicotine [GO:0071316]; cerebral cortex development [GO:0021987]; circadian sleep/wake cycle [GO:0042745]; dopamine biosynthetic process [GO:0042416]; dopamine biosynthetic process from tyrosine [GO:0006585]; eating behavior [GO:0042755]; embryonic camera-type eye morphogenesis [GO:0048596]; epinephrine biosynthetic process [GO:0042418]; eye photoreceptor cell development [GO:0042462]; fatty acid metabolic process [GO:0006631]; glycoside metabolic process [GO:0016137]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; isoquinoline alkaloid metabolic process [GO:0033076]; learning [GO:0007612]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; multicellular organism aging [GO:0010259]; neurotransmitter biosynthetic process [GO:0042136]; norepinephrine biosynthetic process [GO:0042421]; phthalate metabolic process [GO:0018963]; phytoalexin metabolic process [GO:0052314]; pigmentation [GO:0043473]; regulation of heart contraction [GO:0008016]; response to activity [GO:0014823]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to ether [GO:0045472]; response to herbicide [GO:0009635]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to isolation stress [GO:0035900]; response to light stimulus [GO:0009416]; response to lipopolysaccharide [GO:0032496]; response to nutrient levels [GO:0031667]; response to peptide hormone [GO:0043434]; response to pyrethroid [GO:0046684]; response to salt stress [GO:0009651]; response to water deprivation [GO:0009414]; response to zinc ion [GO:0010043]; sensory perception of sound [GO:0007605]; social behavior [GO:0035176]; sphingolipid metabolic process [GO:0006665]; synaptic transmission, dopaminergic [GO:0001963]; terpene metabolic process [GO:0042214]; visual perception [GO:0007601]	L-phenylalanine catabolic process [GO:0006559]	aminergic neurotransmitter loading into synaptic vesicle [GO:0015842]; anatomical structure morphogenesis [GO:0009653]; animal organ morphogenesis [GO:0009887]; catecholamine biosynthetic process [GO:0042423]; cellular response to alkaloid [GO:0071312]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to manganese ion [GO:0071287]; cellular response to nicotine [GO:0071316]; cerebral cortex development [GO:0021987]; circadian sleep/wake cycle [GO:0042745]; dopamine biosynthetic process [GO:0042416]; dopamine biosynthetic process from tyrosine [GO:0006585]; eating behavior [GO:0042755]; embryonic camera-type eye morphogenesis [GO:0048596]; epinephrine biosynthetic process [GO:0042418]; eye photoreceptor cell development [GO:0042462]; fatty acid metabolic process [GO:0006631]; glycoside metabolic process [GO:0016137]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; isoquinoline alkaloid metabolic process [GO:0033076]; learning [GO:0007612]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; multicellular organism aging [GO:0010259]; neurotransmitter biosynthetic process [GO:0042136]; norepinephrine biosynthetic process [GO:0042421]; phthalate metabolic process [GO:0018963]; phytoalexin metabolic process [GO:0052314]; pigmentation [GO:0043473]; regulation of heart contraction [GO:0008016]; response to activity [GO:0014823]; response to amphetamine [GO:0001975]; response to corticosterone [GO:0051412]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to ether [GO:0045472]; response to herbicide [GO:0009635]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to isolation stress [GO:0035900]; response to light stimulus [GO:0009416]; response to lipopolysaccharide [GO:0032496]; response to nutrient levels [GO:0031667]; response to peptide hormone [GO:0043434]; response to pyrethroid [GO:0046684]; response to salt stress [GO:0009651]; response to water deprivation [GO:0009414]; response to zinc ion [GO:0010043]; sensory perception of sound [GO:0007605]; social behavior [GO:0035176]; sphingolipid metabolic process [GO:0006665]; synaptic transmission, dopaminergic [GO:0001963]; terpene metabolic process [GO:0042214]; visual perception [GO:0007601]		axon [GO:0030424]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome membrane [GO:0033162]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perikaryon [GO:0043204]; smooth endoplasmic reticulum [GO:0005790]; synaptic vesicle [GO:0008021]; terminal bouton [GO:0043195]	iron ion binding [GO:0005506]; phenylalanine 4-monooxygenase activity [GO:0004505]	amino acid binding [GO:0016597]; dopamine binding [GO:0035240]; enzyme binding [GO:0019899]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; oxygen binding [GO:0019825]; protein domain specific binding [GO:0019904]; tetrahydrobiopterin binding [GO:0034617]; tyrosine 3-monooxygenase activity [GO:0004511]
d3td2a__d3tcka___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]	translation [GO:0006412]	translation [GO:0006412]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	aminoacyl-tRNA hydrolase activity [GO:0004045]	aminoacyl-tRNA hydrolase activity [GO:0004045]
d3td3b1_d1r1ma___1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; host cell mitochondrion [GO:0033650]; pore complex [GO:0046930]; porin activity [GO:0015288]; ion transport [GO:0006811]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; pore complex [GO:0046930]; porin activity [GO:0015288]; ion transport [GO:0006811]	ion transport [GO:0006811]; pathogenesis [GO:0009405]	ion transport [GO:0006811]	cell outer membrane [GO:0009279]; host cell mitochondrion [GO:0033650]; pore complex [GO:0046930]	cell outer membrane [GO:0009279]; pore complex [GO:0046930]	porin activity [GO:0015288]	porin activity [GO:0015288]
d3td4c1_d2w8bc___1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; host cell mitochondrion [GO:0033650]; pore complex [GO:0046930]; porin activity [GO:0015288]; ion transport [GO:0006811]; pathogenesis [GO:0009405]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]; cell cycle [GO:0007049]; cell division [GO:0051301]	ion transport [GO:0006811]; pathogenesis [GO:0009405]	cell cycle [GO:0007049]; cell division [GO:0051301]	cell outer membrane [GO:0009279]; host cell mitochondrion [GO:0033650]; pore complex [GO:0046930]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]	porin activity [GO:0015288]	
d3td4d1_d5lkwb___1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; host cell mitochondrion [GO:0033650]; pore complex [GO:0046930]; porin activity [GO:0015288]; ion transport [GO:0006811]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell cycle [GO:0007049]; cell division [GO:0051301]	ion transport [GO:0006811]; pathogenesis [GO:0009405]	cell cycle [GO:0007049]; cell division [GO:0051301]	cell outer membrane [GO:0009279]; host cell mitochondrion [GO:0033650]; pore complex [GO:0046930]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	porin activity [GO:0015288]	
d3td4f1_d2hqse2__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; host cell mitochondrion [GO:0033650]; pore complex [GO:0046930]; porin activity [GO:0015288]; ion transport [GO:0006811]; pathogenesis [GO:0009405]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]; cell cycle [GO:0007049]; cell division [GO:0051301]	ion transport [GO:0006811]; pathogenesis [GO:0009405]	cell cycle [GO:0007049]; cell division [GO:0051301]	cell outer membrane [GO:0009279]; host cell mitochondrion [GO:0033650]; pore complex [GO:0046930]	cell division site [GO:0032153]; cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; intrinsic component of periplasmic side of cell outer membrane [GO:0031246]	porin activity [GO:0015288]	
d3td4f1_d4zhvb___1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; host cell mitochondrion [GO:0033650]; pore complex [GO:0046930]; porin activity [GO:0015288]; ion transport [GO:0006811]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	ion transport [GO:0006811]; pathogenesis [GO:0009405]		cell outer membrane [GO:0009279]; host cell mitochondrion [GO:0033650]; pore complex [GO:0046930]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	porin activity [GO:0015288]	
d3td4g1_d2aizp1__1			Proteobacteria	Proteobacteria	cell outer membrane [GO:0009279]; host cell mitochondrion [GO:0033650]; pore complex [GO:0046930]; porin activity [GO:0015288]; ion transport [GO:0006811]; pathogenesis [GO:0009405]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]; cell cycle [GO:0007049]; cell division [GO:0051301]	ion transport [GO:0006811]; pathogenesis [GO:0009405]	cell cycle [GO:0007049]; cell division [GO:0051301]	cell outer membrane [GO:0009279]; host cell mitochondrion [GO:0033650]; pore complex [GO:0046930]	cell outer membrane [GO:0009279]; integral component of membrane [GO:0016021]	porin activity [GO:0015288]	
d3tddb__d4qwkq___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3tddd__d4jsun___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3tddd__d5l6bs___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3tddg__d4hnpf___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3tddh__d4qvnf___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3tddj__d2iwma___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	penicillin amidase activity [GO:0008953]
d3tddl__d4qz0t___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3tddq__d4qw0y___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3tddz__d5d0sa___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3tdea2_d1fuga3__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d3tdea3_d1qm4b1__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]
d3tdeb2_d1o9tb3__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]
d3tdec2_d1p7lb3__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d3tdec3_d1qm4b2__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]; ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]; methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	methionine catabolic process [GO:0009087]; one-carbon metabolic process [GO:0006730]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; S-adenosylmethionine biosynthetic process [GO:0006556]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; nuclear matrix [GO:0016363]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]	ADP binding [GO:0043531]; amino acid binding [GO:0016597]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; protein dimerization activity [GO:0046983]; protein homodimerization activity [GO:0042803]
d3tded1_d1p7la2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d3tded2_d1rg9c1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d3tded3_d1mxca1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	cytosol [GO:0005829]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]; one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]; S-adenosylmethionine cycle [GO:0033353]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; methionine adenosyltransferase activity [GO:0004478]; potassium ion binding [GO:0030955]
d3tdhc2_d2qh1b1__1	Fungi		Ascomycota	Euryarchaeota	cytoplasm [GO:0005737]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein kinase binding [GO:0019901]; cellular response to glucose starvation [GO:0042149]; invasive growth in response to glucose limitation [GO:0001403]; positive regulation of pseudohyphal growth [GO:2000222]; protein phosphorylation [GO:0006468]; regulation of protein complex assembly [GO:0043254]; regulation of protein kinase activity [GO:0045859]; replicative cell aging [GO:0001302]; signal transduction [GO:0007165]	metal ion binding [GO:0046872]	cellular response to glucose starvation [GO:0042149]; invasive growth in response to glucose limitation [GO:0001403]; positive regulation of pseudohyphal growth [GO:2000222]; protein phosphorylation [GO:0006468]; regulation of protein complex assembly [GO:0043254]; regulation of protein kinase activity [GO:0045859]; replicative cell aging [GO:0001302]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		protein kinase binding [GO:0019901]	metal ion binding [GO:0046872]
d3tdjb1_d1pc3b___1	Metazoa		Chordata	Actinobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; cell surface [GO:0009986]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; phosphate ion binding [GO:0042301]; cell adhesion [GO:0007155]; cellular response to phosphate starvation [GO:0016036]; pathogenesis [GO:0009405]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	cell adhesion [GO:0007155]; cellular response to phosphate starvation [GO:0016036]; pathogenesis [GO:0009405]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; cell surface [GO:0009986]; cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	phosphate ion binding [GO:0042301]
d3tdla1_d4n0fd2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3te7a__d3gfqd___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	FMN binding [GO:0010181]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d3te7b__d1flva___1	Metazoa		Chordata	Cyanobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3teaa__d3r37b___1			Actinobacteria	Actinobacteria	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]					4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]	4-hydroxybenzoyl-CoA thioesterase activity [GO:0018739]
d3tefa__d4filb___1			Proteobacteria	Firmicutes	outer membrane-bounded periplasmic space [GO:0030288]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	iron ion transport [GO:0006826]		outer membrane-bounded periplasmic space [GO:0030288]			metal ion binding [GO:0046872]
d3tehb2_d4r4qa1__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]; phenylalanyl-tRNA aminoacylation [GO:0006432]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]; damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]; base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	phenylalanyl-tRNA aminoacylation [GO:0006432]	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; protein localization to chromosome [GO:0034502]; regulation of cellular response to heat [GO:1900034]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomere maintenance via telomerase [GO:0007004]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	cytoplasm [GO:0005737]	DNA replication factor A complex [GO:0005662]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; site of DNA damage [GO:0090734]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phenylalanine-tRNA ligase activity [GO:0004826]; tRNA binding [GO:0000049]	damaged DNA binding [GO:0003684]; G-rich strand telomeric DNA binding [GO:0098505]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; single-stranded DNA binding [GO:0003697]; single-stranded telomeric DNA binding [GO:0043047]
d3temb__d1j8qa___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]
d3tend__d2a8cb___1			Crenarchaeota	Proteobacteria	carbonate dehydratase activity [GO:0004089]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; hydrogen sulfide biosynthetic process [GO:0070814]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	hydrogen sulfide biosynthetic process [GO:0070814]	carbon utilization [GO:0015976]			carbonate dehydratase activity [GO:0004089]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3tenf__d3lasa___1			Crenarchaeota	Firmicutes	carbonate dehydratase activity [GO:0004089]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; hydrogen sulfide biosynthetic process [GO:0070814]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	hydrogen sulfide biosynthetic process [GO:0070814]				carbonate dehydratase activity [GO:0004089]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3tenh__d4o1jb___1		Fungi	Crenarchaeota	Ascomycota	carbonate dehydratase activity [GO:0004089]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; hydrogen sulfide biosynthetic process [GO:0070814]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; carbon utilization [GO:0015976]	hydrogen sulfide biosynthetic process [GO:0070814]	carbon utilization [GO:0015976]			carbonate dehydratase activity [GO:0004089]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3tewa2_d4lhkb___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process in other organism [GO:0044533]; protein homooligomerization [GO:0051260]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	metal ion binding [GO:0046872]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process in other organism [GO:0044533]; protein homooligomerization [GO:0051260]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]		extracellular region [GO:0005576]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]
d3tf1a__d1sz7a___1		Metazoa	Firmicutes	Chordata	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	cis-Golgi network membrane [GO:0033106]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; TRAPP complex [GO:0030008]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]	signal transduction [GO:0007165]	COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]	integral component of membrane [GO:0016021]	cis-Golgi network membrane [GO:0033106]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; TRAPP complex [GO:0030008]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d3tf4b1_d1lf9a1__1			Actinobacteria	Firmicutes	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; polysaccharide metabolic process [GO:0005976]	cellulose catabolic process [GO:0030245]	polysaccharide metabolic process [GO:0005976]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]	carbohydrate binding [GO:0030246]; glucan 1,4-alpha-glucosidase activity [GO:0004339]
d3tfqa__d5ff9d___1	Metazoa	Viridiplantae	Chordata	Streptophyta	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	oxidoreductase activity [GO:0016491]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	oxidoreductase activity [GO:0016491]
d3tfqe__d1mg5a___1	Metazoa	Metazoa	Chordata	Arthropoda	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; acetaldehyde metabolic process [GO:0006117]; alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; behavioral response to ethanol [GO:0048149]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; oxidation-reduction process [GO:0055114]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	acetaldehyde metabolic process [GO:0006117]; alcohol catabolic process [GO:0046164]; alcohol metabolic process [GO:0006066]; behavioral response to ethanol [GO:0048149]; ethanol metabolic process [GO:0006067]; ethanol oxidation [GO:0006069]; oxidation-reduction process [GO:0055114]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	acetaldehyde dehydrogenase (acetylating) activity [GO:0008774]; alcohol dehydrogenase (NAD+) activity [GO:0004022]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]
d3tfqe__d4fccl2__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cellular amino acid metabolic process [GO:0006520]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d3tg0a__d1shnb1__1		Metazoa	Proteobacteria	Arthropoda	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	alkaline phosphatase activity [GO:0004035]; metal ion binding [GO:0046872]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	alkaline phosphatase activity [GO:0004035]; metal ion binding [GO:0046872]
d3tg0a__d3t00a___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]; dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]	metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]	dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		alkaline phosphatase activity [GO:0004035]; hydrogenase (acceptor) activity [GO:0033748]; magnesium ion binding [GO:0000287]; oxidoreductase activity, acting on phosphorus or arsenic in donors [GO:0030613]; phosphoprotein phosphatase activity [GO:0004721]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; NADH pyrophosphatase activity [GO:0035529]; phosphonoacetate hydrolase activity [GO:0047400]
d3tgba__d4i3be___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cytoplasm [GO:0005737]; lipid binding [GO:0008289]; bioluminescence [GO:0008218]	vasodilation [GO:0042311]	bioluminescence [GO:0008218]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	lipid binding [GO:0008289]
d3tgca__d4gkca___1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	cytosol [GO:0005829]; retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	vasodilation [GO:0042311]	epidermis development [GO:0008544]; retinoid metabolic process [GO:0001523]; vitamin A metabolic process [GO:0006776]	extracellular region [GO:0005576]	cytosol [GO:0005829]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]	retinal binding [GO:0016918]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3tgla__d4ffva2__1	Fungi	Metazoa	Mucoromycota	Chordata	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3tgvc1_d3a6rb___1			Proteobacteria	Proteobacteria	coenzyme F420 binding [GO:0070967]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; heme transport [GO:0015886]	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]	heme transport [GO:0015886]	oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	coenzyme F420 binding [GO:0070967]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	cofactor binding [GO:0048037]
d3tgvc1_d5bnca___1			Proteobacteria	Actinobacteria	coenzyme F420 binding [GO:0070967]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; heme transport [GO:0015886]	cofactor binding [GO:0048037]	heme transport [GO:0015886]				coenzyme F420 binding [GO:0070967]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	cofactor binding [GO:0048037]
d3tgvd1_d4ywnb___1			Proteobacteria	Actinobacteria	coenzyme F420 binding [GO:0070967]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; heme transport [GO:0015886]	FMN binding [GO:0010181]	heme transport [GO:0015886]				coenzyme F420 binding [GO:0070967]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]	FMN binding [GO:0010181]
d3tgwb3_d4yxwc3__1		Metazoa	Euryarchaeota	Chordata	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3tgza1_d5ecmc1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d3tgza2_d2hqto___1	Metazoa	Fungi	Chordata	Ascomycota	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]; enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]; positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	positive regulation of ligase activity [GO:0051351]; tRNA aminoacylation for protein translation [GO:0006418]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; methionyl glutamyl tRNA synthetase complex [GO:0017102]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	enzyme activator activity [GO:0008047]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-3-phosphate binding [GO:0032266]; tRNA binding [GO:0000049]
d3th2t2_d2b7dt1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]; calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	animal organ regeneration [GO:0031100]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; circadian rhythm [GO:0007623]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell migration [GO:0030335]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of platelet-derived growth factor receptor signaling pathway [GO:0010641]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; protein processing [GO:0016485]; response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904612]; response to astaxanthin [GO:1905217]; response to carbon dioxide [GO:0010037]; response to cholesterol [GO:0070723]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to genistein [GO:0033595]; response to growth hormone [GO:0060416]; response to hypoxia [GO:0001666]; response to Thyroid stimulating hormone [GO:1904400]; response to thyrotropin-releasing hormone [GO:1905225]; response to thyroxine [GO:0097068]; response to vitamin K [GO:0032571]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; serine-type peptidase complex [GO:1905286]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]	calcium ion binding [GO:0005509]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]
d3th7b__d3nipe___1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	putrescine biosynthetic process from arginine, using agmatinase [GO:0033389]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	agmatinase activity [GO:0008783]; guanidinopropionase activity [GO:0047972]; metal ion binding [GO:0046872]
d3theb__d3e8zb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process to ornithine [GO:0019547]; arginine metabolic process [GO:0006525]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; female pregnancy [GO:0007565]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to lipopolysaccharide [GO:0032496]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to peptide hormone [GO:0043434]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to wounding [GO:0009611]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d3thha__d4ie2b___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d3thhb__d4ixuc___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; arginine catabolic process to ornithine [GO:0019547]; innate immune response [GO:0045087]; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905403]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine (C-C motif) ligand 4 production [GO:0071644]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of interleukin-13 secretion [GO:2000666]; negative regulation of interleukin-17 secretion [GO:1905077]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; negative regulation of type 2 immune response [GO:0002829]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of cellular senescence [GO:2000774]; regulation of interleukin-1 beta secretion [GO:0050706]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; striated muscle contraction [GO:0006941]; urea cycle [GO:0000050]; ureteric bud development [GO:0001657]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d3thjb__d2pqoa___1	Metazoa		Chordata		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]		adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]		arginase activity [GO:0004053]; manganese ion binding [GO:0030145]	
d3thml2_d1jnha2__1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell surface [GO:0009986]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to amino acid starvation [GO:0034198]; cellular response to hyperoxia [GO:0071455]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway [GO:0097191]; Fas signaling pathway [GO:0036337]; immune response [GO:0006955]; necroptotic signaling pathway [GO:0097527]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of protein phosphorylation [GO:0001934]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of stress-activated MAPK cascade [GO:0032872]; signal transduction [GO:0007165]	plasma membrane [GO:0005886]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to amino acid starvation [GO:0034198]; cellular response to hyperoxia [GO:0071455]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway [GO:0097191]; Fas signaling pathway [GO:0036337]; immune response [GO:0006955]; necroptotic signaling pathway [GO:0097527]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of protein phosphorylation [GO:0001934]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of stress-activated MAPK cascade [GO:0032872]; signal transduction [GO:0007165]		CD95 death-inducing signaling complex [GO:0031265]; cell surface [GO:0009986]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]	plasma membrane [GO:0005886]	calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]	
d3thml2_d3miqf___1	Metazoa		Chordata		CD95 death-inducing signaling complex [GO:0031265]; cell surface [GO:0009986]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to amino acid starvation [GO:0034198]; cellular response to hyperoxia [GO:0071455]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway [GO:0097191]; Fas signaling pathway [GO:0036337]; immune response [GO:0006955]; necroptotic signaling pathway [GO:0097527]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of protein phosphorylation [GO:0001934]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of stress-activated MAPK cascade [GO:0032872]; signal transduction [GO:0007165]		activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to amino acid starvation [GO:0034198]; cellular response to hyperoxia [GO:0071455]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway [GO:0097191]; Fas signaling pathway [GO:0036337]; immune response [GO:0006955]; necroptotic signaling pathway [GO:0097527]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of protein phosphorylation [GO:0001934]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of stress-activated MAPK cascade [GO:0032872]; signal transduction [GO:0007165]		CD95 death-inducing signaling complex [GO:0031265]; cell surface [GO:0009986]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]		calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]	
d3thqa__d3o05b___1		Fungi	Euryarchaeota	Ascomycota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	glutaminase complex [GO:1903600]; amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]; cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cellular amino acid metabolic process [GO:0006520]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; vitamin B6 biosynthetic process [GO:0042819]		glutaminase complex [GO:1903600]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]	amine-lyase activity [GO:0016843]; pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [GO:0036381]
d3thub1_d1ebgb2__1		Fungi	Proteobacteria	Ascomycota	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3thuc2_d2dw7j1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	protein homooligomerization [GO:0051260]			magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]
d3ti2d__d4r7ub___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytoplasm [GO:0005737]; UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity [GO:0008760]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylgalactosamine biosynthetic process [GO:0019277]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylgalactosamine biosynthetic process [GO:0019277]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-phosphoshikimate 1-carboxyvinyltransferase activity [GO:0003866]	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity [GO:0008760]
d3ti3b__d4k1ja___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3ti5a__d4cpob___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3ti5b__d2htyd___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3ti6b__d3cyea___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3ti8a__d4gzxa___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d3tiba__d4yw2b2__1			Negarnaviricota	Firmicutes	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d3ticc__d4gezc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3tiia1_d3g8db1__1	Metazoa		Chordata	Proteobacteria	nucleotide binding [GO:0000166]; cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]	cellular protein modification process [GO:0006464]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of fatty acid biosynthetic process [GO:0045717]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	nucleotide binding [GO:0000166]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d3tiib1_d1a9xg3__1	Metazoa		Chordata	Proteobacteria	nucleotide binding [GO:0000166]; cellular protein modification process [GO:0006464]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cellular protein modification process [GO:0006464]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]		carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d3tika1_d5b2xb___1				Firmicutes	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d3tioa__d3vnpa1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; protein homotrimerization [GO:0070207]	metal ion binding [GO:0046872]	protein homotrimerization [GO:0070207]		cytosol [GO:0005829]		identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d3tioe__d1krvb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]; galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]; lactose biosynthetic process [GO:0005989]	protein homotrimerization [GO:0070207]	lactose biosynthetic process [GO:0005989]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	galactoside O-acetyltransferase activity [GO:0008870]; identical protein binding [GO:0042802]
d3tiof__d4h7ob___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; protein homotrimerization [GO:0070207]	cytosol [GO:0005829]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]	protein homotrimerization [GO:0070207]	cysteine biosynthetic process from serine [GO:0006535]	cytosol [GO:0005829]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	serine O-acetyltransferase activity [GO:0009001]
d3tisb__d3i3aa___1			Proteobacteria	Spirochaetes	cytosol [GO:0005829]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; protein homotrimerization [GO:0070207]	cytoplasm [GO:0005737]; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]; lipid A biosynthetic process [GO:0009245]	protein homotrimerization [GO:0070207]	lipid A biosynthetic process [GO:0009245]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [GO:0008780]
d3tjba__d4yqmc1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d3tjbb__d3zfba1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3tjbd__d5l6xa1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3tjel1_d2ny2b2__1	Metazoa	Metazoa	Chordata	Chordata	CD95 death-inducing signaling complex [GO:0031265]; cell surface [GO:0009986]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to amino acid starvation [GO:0034198]; cellular response to hyperoxia [GO:0071455]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway [GO:0097191]; Fas signaling pathway [GO:0036337]; immune response [GO:0006955]; necroptotic signaling pathway [GO:0097527]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of protein phosphorylation [GO:0001934]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of stress-activated MAPK cascade [GO:0032872]; signal transduction [GO:0007165]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to amino acid starvation [GO:0034198]; cellular response to hyperoxia [GO:0071455]; cellular response to mechanical stimulus [GO:0071260]; extrinsic apoptotic signaling pathway [GO:0097191]; Fas signaling pathway [GO:0036337]; immune response [GO:0006955]; necroptotic signaling pathway [GO:0097527]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of protein phosphorylation [GO:0001934]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of stress-activated MAPK cascade [GO:0032872]; signal transduction [GO:0007165]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	CD95 death-inducing signaling complex [GO:0031265]; cell surface [GO:0009986]; cytosol [GO:0005829]; death-inducing signaling complex [GO:0031264]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3tjfa__d3a2vf___1	Metazoa		Chordata	Crenarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytoplasm [GO:0005737]; antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; oxidation-reduction process [GO:0055114]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]; cytoplasm [GO:0005737]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	antioxidant activity [GO:0016209]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d3tjfb__d2x64c1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	transferase activity [GO:0016740]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]		cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]		protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	transferase activity [GO:0016740]
d3tjfc__d4fh8i___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	peroxiredoxin activity [GO:0051920]
d3tjfd__d5jwob___1	Metazoa		Chordata	Cyanobacteria	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	circadian rhythm [GO:0007623]; negative regulation of phosphorylation [GO:0042326]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]		protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	
d3tjga__d1r26a1__1	Metazoa		Chordata		cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; mitochondrion [GO:0005739]; disulfide oxidoreductase activity [GO:0015036]; protein disulfide isomerase activity [GO:0003756]; cell redox homeostasis [GO:0045454]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]; mitochondrion [GO:0005739]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	disulfide oxidoreductase activity [GO:0015036]; protein disulfide isomerase activity [GO:0003756]
d3tjgb__d5djlb1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3tjgb__d5jcgd1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; alkyl hydroperoxide reductase activity [GO:0008785]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of apoptotic process [GO:0043066]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	alkyl hydroperoxide reductase activity [GO:0008785]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d3tjgc__d1hncb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]
d3tjgd__d1zyek1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d3tjia1_d4kemb1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	D(-)-tartrate dehydratase activity [GO:0047808]; metal ion binding [GO:0046872]	cellular amino acid catabolic process [GO:0009063]				magnesium ion binding [GO:0000287]	D(-)-tartrate dehydratase activity [GO:0047808]; metal ion binding [GO:0046872]
d3tjia2_d1r0mc1__1			Proteobacteria	Deinococcus-Thermus	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	cellular amino acid catabolic process [GO:0009063]	menaquinone biosynthetic process [GO:0009234]			magnesium ion binding [GO:0000287]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3tjid2_d2chra1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]	cellular amino acid catabolic process [GO:0009063]	aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]			magnesium ion binding [GO:0000287]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d3tjta2_d3evkc2__1			Firmicutes	Crenarchaeota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	manganese ion binding [GO:0030145]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3tjta2_d4h3eb2__1			Firmicutes		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3tjua__d1d3q.1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; membrane [GO:0016020]; serine-type endopeptidase activity [GO:0004252]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	cytoplasm [GO:0005737]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d3tjza__d4v0la1__1	Metazoa	Viridiplantae	Chordata	Chlorophyta	COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; structural molecule activity [GO:0005198]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; organelle transport along microtubule [GO:0072384]; protein secretion [GO:0009306]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]	axoneme [GO:0005930]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; cilium assembly [GO:0060271]; intracellular protein transport [GO:0006886]; protein localization to cilium [GO:0061512]; vesicle-mediated transport [GO:0016192]	endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; organelle transport along microtubule [GO:0072384]; protein secretion [GO:0009306]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]	cilium assembly [GO:0060271]; intracellular protein transport [GO:0006886]; protein localization to cilium [GO:0061512]; vesicle-mediated transport [GO:0016192]	COPI vesicle coat [GO:0030126]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]	axoneme [GO:0005930]; cytoplasm [GO:0005737]	structural molecule activity [GO:0005198]	GTP binding [GO:0005525]
d3tk6a__d1dy8.1__1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA binding [GO:0003677]; DNA/DNA annealing activity [GO:1990814]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host G1/S transition checkpoint [GO:0039645]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; pore formation by virus in membrane of host cell [GO:0039707]; positive regulation of apoptotic process by virus [GO:0060139]; protein complex oligomerization [GO:0051259]; RNA stabilization [GO:0043489]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host TRAF activity [GO:0039547]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transformation of host cell by virus [GO:0019087]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell cytoplasm [GO:0030430]; host cell cytosol [GO:0044164]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell lipid droplet [GO:0044186]; host cell mitochondrial membrane [GO:0044191]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; protein-DNA complex [GO:0032993]; ribonucleoprotein complex [GO:1990904]; viral envelope [GO:0019031]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA/DNA annealing activity [GO:1990814]; DNA binding [GO:0003677]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; RNA strand annealing activity [GO:0033592]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3tk8a__d4n27c___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]		cytoplasm [GO:0005737]		2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [GO:0008666]	metal ion binding [GO:0046872]; transferase activity [GO:0016740]
d3tk9a__d4xfqa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; membrane [GO:0016020]; serine-type endopeptidase activity [GO:0004252]; apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	apoptotic process [GO:0006915]; cytolysis [GO:0019835]; granzyme-mediated apoptotic signaling pathway [GO:0008626]	induction by virus of host autophagy [GO:0039520]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasm [GO:0005737]; membrane [GO:0016020]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; zinc ion binding [GO:0008270]
d3tkba1_d2zhxi___1	Metazoa		Chordata	Actinobacteria	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; isotype switching [GO:0045190]; negative regulation of apoptotic process [GO:0043066]; somatic hypermutation of immunoglobulin genes [GO:0016446]; viral process [GO:0016032]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	mitochondrion [GO:0005739]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; ribosomal small subunit binding [GO:0043024]; uracil DNA N-glycosylase activity [GO:0004844]	uracil DNA N-glycosylase activity [GO:0004844]
d3tkdb__d4rpoc___1	Metazoa		Chordata	Proteobacteria	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; aromatic compound catabolic process [GO:0019439]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	aromatic compound catabolic process [GO:0019439]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3tkgc__d5ozta___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3tkpa__d2pbjb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	electron transfer activity [GO:0009055]; glutathione binding [GO:0043295]; heme binding [GO:0020037]; lyase activity [GO:0016829]; prostaglandin-E synthase activity [GO:0050220]; protein disulfide oxidoreductase activity [GO:0015035]
d3tkpb__d1glpb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione metabolic process [GO:0006749]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of neutrophil aggregation [GO:2000429]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of peroxidase activity [GO:2000469]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to nutrient levels [GO:0031667]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; TRAF2-GSTP1 complex [GO:0097057]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; protein kinase binding [GO:0019901]; S-nitrosoglutathione binding [GO:0035730]
d3tkpb__d1xcca___1	Metazoa		Chordata	Apicomplexa	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	peroxiredoxin activity [GO:0051920]
d3tkqa__d1f3ba2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytosol [GO:0005829]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; steroid delta-isomerase activity [GO:0004769]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to bacterium [GO:0009617]; response to stilbenoid [GO:0035634]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cytosol [GO:0005829]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; steroid delta-isomerase activity [GO:0004769]
d3tkqb__d1a2ma___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; cellular response to antibiotic [GO:0071236]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	protein disulfide isomerase activity [GO:0003756]; protein disulfide oxidoreductase activity [GO:0015035]
d3tkqe__d1zyei1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d3tkra__d3hxsb___1	Metazoa		Chordata	Bacteroidetes	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]
d3tkrb__d3ztld___1	Metazoa	Metazoa	Chordata	Platyhelminthes	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d3tkrc__d3tkqb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d3tkrc__d3wgdh1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; isomerase activity [GO:0016853]; apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	isomerase activity [GO:0016853]
d3tkrf__d2vm2d___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	protein disulfide oxidoreductase activity [GO:0015035]
d3tkrf__d5dvbi1__1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to oxidative stress [GO:0006979]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to oxidative stress [GO:0006979]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	peroxiredoxin activity [GO:0051920]; thioredoxin peroxidase activity [GO:0008379]
d3tkrg__d3zvjg___1	Metazoa	Metazoa	Chordata	Platyhelminthes	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cell [GO:0005623]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]
d3tkri__d3tgza1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]
d3tkrj__d2c3na1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]
d3tkwa__d2pynb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3tkyb2_d4gf5j___1	Viridiplantae		Streptophyta	Actinobacteria	(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]	O-methyltransferase activity [GO:0008171]					(iso)eugenol O-methyltransferase activity [GO:0050630]; protein dimerization activity [GO:0046983]; S-adenosyl-L-methionine:eugenol-O-methyltransferase activity [GO:0102719]	O-methyltransferase activity [GO:0008171]
d3tl9a__d2f80a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3tlha__d5lwta___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3tlkc1_d5vq4c___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]; cellular response to DNA damage stimulus [GO:0006974]; ferric-enterobactin import into cell [GO:0015685]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cellular response to DNA damage stimulus [GO:0006974]; ferric-enterobactin import into cell [GO:0015685]	nitrogen fixation [GO:0009399]	cell [GO:0005623]; outer membrane-bounded periplasmic space [GO:0030288]	molybdenum-iron nitrogenase complex [GO:0016612]		ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d3tloa__d1d3t.1__1		Metazoa		Chordata	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d3tlob__d1soza2__1				Proteobacteria	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]; identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cellular response to misfolded protein [GO:0071218]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	integral component of external side of plasma membrane [GO:0071575]; outer membrane-bounded periplasmic space [GO:0030288]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3tlra1_d1fvdd2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3tlrc1_d3o3ab1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3tm6b1_d5iw1f1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3tm6c1_d1hklh1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3tm6e1_d2z31a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3tm6f1_d2q76c1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3tm6f1_d4o9hl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]
d3tm6g1_d2fx7h2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion [GO:0019012]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	structural molecule activity [GO:0005198]
d3tm6g1_d3cfkk1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3tm9a__d1kn1b___1			Proteobacteria	Rhodophyta	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	response to nitrosative stress [GO:0051409]	oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3tmea__d3osoa___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	extracellular region [GO:0005576]; membrane [GO:0016020]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]			extracellular region [GO:0005576]; membrane [GO:0016020]	extracellular region [GO:0005576]; membrane [GO:0016020]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
d3tmja__d4kp5a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; chloride ion homeostasis [GO:0055064]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]; chloride ion homeostasis [GO:0055064]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3tmka__d1yr6a1__1	Fungi		Ascomycota	Euryarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; nucleoside diphosphate phosphorylation [GO:0006165]	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; nucleoside diphosphate phosphorylation [GO:0006165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	GTP binding [GO:0005525]; hydrolase activity [GO:0016787]
d3tmne__d3dbka___1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; bacterial-type flagellum-dependent swarming motility [GO:0071978]; pathogenesis [GO:0009405]; protein secretion by the type II secretion system [GO:0015628]; protein transport by the Sec complex [GO:0043952]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]		bacterial-type flagellum-dependent swarming motility [GO:0071978]; pathogenesis [GO:0009405]; protein secretion by the type II secretion system [GO:0015628]; protein transport by the Sec complex [GO:0043952]; proteolysis [GO:0006508]; single-species biofilm formation [GO:0044010]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d3tmua__d1l95a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3tmyb__d3ffta___1			Thermotogae	Proteobacteria	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	cytosol [GO:0005829]; acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]; bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	archaeal or bacterial-type flagellum-dependent cell motility [GO:0097588]; chemotaxis [GO:0006935]; phosphorelay signal transduction system [GO:0000160]	bacterial-type flagellum-dependent cell motility [GO:0071973]; chemotaxis [GO:0006935]; internal peptidyl-lysine acetylation [GO:0018393]; phosphorelay signal transduction system [GO:0000160]; protein acetylation [GO:0006473]; signal transduction by protein phosphorylation [GO:0023014]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	metal ion binding [GO:0046872]	acetyltransferase activity [GO:0016407]; magnesium ion binding [GO:0000287]
d3tn1b1_d2ra4a___1		Metazoa		Chordata		cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; signaling receptor binding [GO:0005102]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; regulation of cell shape [GO:0008360]; signal transduction [GO:0007165]		antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell-cell signaling [GO:0007267]; cellular calcium ion homeostasis [GO:0006874]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; chemokine-mediated signaling pathway [GO:0070098]; chemotaxis [GO:0006935]; cytoskeleton organization [GO:0007010]; eosinophil chemotaxis [GO:0048245]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; killing of cells of other organism [GO:0031640]; lymphocyte chemotaxis [GO:0048247]; monocyte chemotaxis [GO:0002548]; neutrophil chemotaxis [GO:0030593]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; regulation of cell shape [GO:0008360]; signal transduction [GO:0007165]		cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]		CCR chemokine receptor binding [GO:0048020]; chemokine activity [GO:0008009]; signaling receptor binding [GO:0005102]
d3tn8b2_d4bcpd1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d3tn93__d4y4yc___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d3tnla1_d3mvqa1__1			Firmicutes		cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	
d3tnla2_d4bb6a___1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytosol [GO:0005829]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d3tnlb1_d1nqta2__1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytosol [GO:0005829]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d3tnlb1_d4b4ub1__1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; nucleotide binding [GO:0000166]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; nucleotide binding [GO:0000166]
d3tnld2_d2jkvf1__1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate catabolic process [GO:0046177]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	D-gluconate catabolic process [GO:0046177]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]
d3tnmb1_d2cjvh___1												
d3tnmb1_d4bswa2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3tnmb2_d5gs1d1__1												
d3tnnb2_d1t66c1__1		Metazoa		Chordata								
d3tnnf1_d4xakl1__1						host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]		endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; pathogenesis [GO:0009405]; receptor-mediated virion attachment to host cell [GO:0046813]		host cell endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0044173]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		
d3tnnl1_d2axfa1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3tnnl2_d1cloh2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		antibacterial humoral response [GO:0019731]; antibody-dependent cellular cytotoxicity [GO:0001788]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3tnva__d2bjea___1			Euryarchaeota	Crenarchaeota	acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	acylphosphatase activity [GO:0003998]					acylphosphatase activity [GO:0003998]; hydrolase activity [GO:0016787]	acylphosphatase activity [GO:0003998]
d3tnwb1_d3lq5b1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3tnwd1_d2pk2a1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cyclin/CDK positive transcription elongation factor complex [GO:0008024]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 7SK snRNA binding [GO:0097322]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; DNA binding [GO:0003677]; protein kinase binding [GO:0019901]; RNA polymerase binding [GO:0070063]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of mRNA polyadenylation [GO:1900364]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of mRNA polyadenylation [GO:1900364]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	cyclin/CDK positive transcription elongation factor complex [GO:0008024]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	7SK snRNA binding [GO:0097322]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; DNA binding [GO:0003677]; protein kinase binding [GO:0019901]; RNA polymerase binding [GO:0070063]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3tnwd1_d2r7gc2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]; androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	androgen receptor signaling pathway [GO:0030521]; aortic valve morphogenesis [GO:0003180]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cell morphogenesis involved in neuron differentiation [GO:0048667]; cellular response to xenobiotic stimulus [GO:0071466]; chromatin remodeling [GO:0006338]; digestive tract development [GO:0048565]; enucleate erythrocyte differentiation [GO:0043353]; G1/S transition of mitotic cell cycle [GO:0000082]; glial cell apoptotic process [GO:0034349]; hepatocyte apoptotic process [GO:0097284]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic cell cycle checkpoint [GO:0007093]; myoblast differentiation [GO:0045445]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of myofibroblast differentiation [GO:1904761]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of tau-protein kinase activity [GO:1902948]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071930]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of extracellular matrix organization [GO:1903055]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein localization to chromosome, centromeric region [GO:0071459]; Ras protein signal transduction [GO:0007265]; regulation of centromere complex assembly [GO:0090230]; regulation of cohesin loading [GO:0071922]; regulation of lipid kinase activity [GO:0043550]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid biorientation [GO:0031134]; skeletal muscle cell differentiation [GO:0035914]; striated muscle cell differentiation [GO:0051146]; tissue homeostasis [GO:0001894]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromatin [GO:0000785]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; Rb-E2F complex [GO:0035189]; spindle [GO:0005819]; SWI/SNF complex [GO:0016514]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	androgen receptor binding [GO:0050681]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; importin-alpha family protein binding [GO:0061676]; kinase binding [GO:0019900]; phosphoprotein binding [GO:0051219]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d3tnya__d3li2a1__1				Firmicutes		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d3to4a2_d5y11b1__1	Metazoa		Chordata	Negarnaviricota	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; virion [GO:0019012]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; virion [GO:0019012]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3to4c1_d4ma1c2__1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3to4d1_d1k5nb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3to4d2_d1zgla1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3to4d2_d4u05b___1	Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3toeb__d4z9eb___1			Euryarchaeota	Euryarchaeota	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]			chromosome [GO:0005694]; cytoplasm [GO:0005737]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]
d3tofa__d3ekta___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3tofb__d2r8na___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3toga__d4gida___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3togd__d2i4da___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3togd__d5ozja___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3toha__d2q55b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3tola__d1rcpa___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3tolc__d5xzjc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3told__d5xzia___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3toma__d3ztza___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3tomc__d4cdya___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3torb__d2j7ae___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]; anaerobic electron transport chain [GO:0019645]; nitrate assimilation [GO:0042128]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; denitrification pathway [GO:0019333]; oxidation-reduction process [GO:0055114]	anaerobic electron transport chain [GO:0019645]; nitrate assimilation [GO:0042128]	denitrification pathway [GO:0019333]; oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide reductase activity [GO:0016966]; nitrite reductase (cytochrome, ammonia-forming) activity [GO:0042279]	heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3toxa__d3ai1a___1			Proteobacteria	Proteobacteria	nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]					nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3toxa__d4ijvd1__1		Metazoa	Proteobacteria	Chordata	nucleotide binding [GO:0000166]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	nucleotide binding [GO:0000166]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d3toxd__d5pgzb___1		Metazoa	Proteobacteria	Chordata	nucleotide binding [GO:0000166]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]		glucocorticoid biosynthetic process [GO:0006704]; glucocorticoid catabolic process [GO:0006713]; lung development [GO:0030324]; regulation of pentose-phosphate shunt [GO:0043456]		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; nuclear membrane [GO:0031965]; rough endoplasmic reticulum [GO:0005791]	nucleotide binding [GO:0000166]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; NADP binding [GO:0050661]; steroid binding [GO:0005496]
d3toxi__d5i7fj___1			Proteobacteria	Proteobacteria	nucleotide binding [GO:0000166]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]			nucleotide binding [GO:0000166]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d3toyc2_d3b97c2__1		Metazoa	Proteobacteria	Chordata	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	cellular amino acid catabolic process [GO:0009063]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]		cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]	cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d3tozb1_d1l1ff2__1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]; cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid biosynthetic process [GO:0008652]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; positive regulation of insulin secretion [GO:0032024]; substantia nigra development [GO:0021762]; tricarboxylic acid metabolic process [GO:0072350]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; leucine binding [GO:0070728]; NAD+ binding [GO:0070403]
d3tozb1_d4fr5a1__1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytosol [GO:0005829]	cytosol [GO:0005829]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d3tozc1_d1nqte2__1		Metazoa	Firmicutes	Chordata	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; tricarboxylic acid metabolic process [GO:0072350]	cytosol [GO:0005829]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	ATP binding [GO:0005524]; glutamate dehydrogenase (NAD+) activity [GO:0004352]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]
d3tozd2_d1bvud1__1			Firmicutes	Euryarchaeota	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d3toze2_d2d3tb3__1			Firmicutes	Proteobacteria	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	fatty acid beta-oxidation [GO:0006635]	cytosol [GO:0005829]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d3tozf1_d1v9le2__1			Firmicutes	Crenarchaeota	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]		NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d3tpwa__d1pkhb___1				Euryarchaeota	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	viral nucleocapsid [GO:0019013]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d3tq3a__d5y5ob___1					viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	viral nucleocapsid [GO:0019013]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3tq4a__d1sm8c___1				Actinobacteria	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	viral nucleocapsid [GO:0019013]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3tq5a__d1q5hb___1		Metazoa		Chordata	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	viral nucleocapsid [GO:0019013]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d3tq5a__d4apz2___1				Firmicutes	viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	viral nucleocapsid [GO:0019013]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3tq7q__d1ixda1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; midbody [GO:0030496]; mitotic spindle astral microtubule end [GO:1905721]; perinuclear region of cytoplasm [GO:0048471]; spindle midzone [GO:0051233]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; cell division [GO:0051301]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; microtubule [GO:0005874]; perinuclear region of cytoplasm [GO:0048471]; spindle [GO:0005819]; Lys48-specific deubiquitinase activity [GO:1990380]; Lys63-specific deubiquitinase activity [GO:0061578]; proline-rich region binding [GO:0070064]; protein kinase binding [GO:0019901]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell cycle [GO:0007049]; homeostasis of number of cells [GO:0048872]; innate immune response [GO:0045087]; necroptotic process [GO:0070266]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of JNK cascade [GO:0046329]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of type I interferon production [GO:0032480]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of cellular protein localization [GO:1903829]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536]; protein linear deubiquitination [GO:1990108]; regulation of B cell differentiation [GO:0045577]; regulation of cilium assembly [GO:1902017]; regulation of inflammatory response [GO:0050727]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of mitotic cell cycle [GO:0007346]; regulation of necroptotic process [GO:0060544]; regulation of protein binding [GO:0043393]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; ripoptosome assembly involved in necroptotic process [GO:1901026]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	cell division [GO:0051301]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of microtubule plus-end binding [GO:1903033]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization [GO:0008104]; protein localization to microtubule [GO:0035372]; protein localization to microtubule plus-end [GO:1904825]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; spindle assembly [GO:0051225]	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment [GO:0043369]; cell cycle [GO:0007049]; homeostasis of number of cells [GO:0048872]; innate immune response [GO:0045087]; necroptotic process [GO:0070266]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of JNK cascade [GO:0046329]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of type I interferon production [GO:0032480]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of cellular protein localization [GO:1903829]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein deubiquitination [GO:0016579]; protein K63-linked deubiquitination [GO:0070536]; protein linear deubiquitination [GO:1990108]; regulation of B cell differentiation [GO:0045577]; regulation of cilium assembly [GO:1902017]; regulation of inflammatory response [GO:0050727]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of mitotic cell cycle [GO:0007346]; regulation of necroptotic process [GO:0060544]; regulation of protein binding [GO:0043393]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; ripoptosome assembly involved in necroptotic process [GO:1901026]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; microtubule organizing center [GO:0005815]; microtubule plus-end [GO:0035371]; midbody [GO:0030496]; mitotic spindle astral microtubule end [GO:1905721]; perinuclear region of cytoplasm [GO:0048471]; spindle midzone [GO:0051233]	centrosome [GO:0005813]; ciliary basal body [GO:0036064]; ciliary tip [GO:0097542]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; microtubule [GO:0005874]; perinuclear region of cytoplasm [GO:0048471]; spindle [GO:0005819]	identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; microtubule plus-end binding [GO:0051010]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]	Lys48-specific deubiquitinase activity [GO:1990380]; Lys63-specific deubiquitinase activity [GO:0061578]; proline-rich region binding [GO:0070064]; protein kinase binding [GO:0019901]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3tqja1_d1ma1d1__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]			cytosol [GO:0005829]		metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d3trfb__d4d6ia1__1			Proteobacteria		cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]	
d3ts5b__d2knea___1	Metazoa	Metazoa	Mollusca	Chordata	myosin complex [GO:0016459]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	basolateral plasma membrane [GO:0016323]; caveola [GO:0005901]; cell [GO:0005623]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic active zone membrane [GO:0099059]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sperm flagellum [GO:0036126]; sperm principal piece [GO:0097228]; T-tubule [GO:0030315]; Z disc [GO:0030018]; ATP binding [GO:0005524]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase inhibitor activity [GO:0036487]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; protein phosphatase 2B binding [GO:0030346]; scaffold protein binding [GO:0097110]; calcium ion export [GO:1901660]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to acetylcholine [GO:1905145]; cellular response to epinephrine stimulus [GO:0071872]; flagellated sperm motility [GO:0030317]; hippocampus development [GO:0021766]; ion transmembrane transport [GO:0034220]; negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0140199]; negative regulation of arginine catabolic process [GO:1900082]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of citrulline biosynthetic process [GO:1903249]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of nitric-oxide synthase activity [GO:0051001]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of the force of heart contraction [GO:0098736]; neural retina development [GO:0003407]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of cardiac conduction [GO:1903779]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of transcription by RNA polymerase II [GO:0006357]; response to hydrostatic pressure [GO:0051599]; spermatogenesis [GO:0007283]; urinary bladder smooth muscle contraction [GO:0014832]		calcium ion export [GO:1901660]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to acetylcholine [GO:1905145]; cellular response to epinephrine stimulus [GO:0071872]; flagellated sperm motility [GO:0030317]; hippocampus development [GO:0021766]; ion transmembrane transport [GO:0034220]; negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0140199]; negative regulation of arginine catabolic process [GO:1900082]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of citrulline biosynthetic process [GO:1903249]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of nitric-oxide synthase activity [GO:0051001]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of the force of heart contraction [GO:0098736]; neural retina development [GO:0003407]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of cardiac conduction [GO:1903779]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of transcription by RNA polymerase II [GO:0006357]; response to hydrostatic pressure [GO:0051599]; spermatogenesis [GO:0007283]; urinary bladder smooth muscle contraction [GO:0014832]	myosin complex [GO:0016459]	basolateral plasma membrane [GO:0016323]; caveola [GO:0005901]; cell [GO:0005623]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic active zone membrane [GO:0099059]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sperm flagellum [GO:0036126]; sperm principal piece [GO:0097228]; T-tubule [GO:0030315]; Z disc [GO:0030018]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	ATP binding [GO:0005524]; calcium transmembrane transporter activity, phosphorylative mechanism [GO:0005388]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; nitric-oxide synthase binding [GO:0050998]; nitric-oxide synthase inhibitor activity [GO:0036487]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; protein phosphatase 2B binding [GO:0030346]; scaffold protein binding [GO:0097110]
d3ts5c__d4ybhb___1	Metazoa	Metazoa	Mollusca	Chordata	myosin complex [GO:0016459]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; advanced glycation end-product receptor activity [GO:0050785]; amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; S100 protein binding [GO:0044548]; scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; astrocyte activation [GO:0048143]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; glucose mediated signaling pathway [GO:0010255]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of blood circulation [GO:1903523]; negative regulation of connective tissue replacement involved in inflammatory response wound healing [GO:1904597]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of long-term synaptic potentiation [GO:1900272]; neuron projection development [GO:0031175]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein localization to membrane [GO:0072657]; regulation of CD4-positive, alpha-beta T cell activation [GO:2000514]; regulation of DNA binding [GO:0051101]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of p38MAPK cascade [GO:1900744]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell mediated cytotoxicity [GO:0001914]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to wounding [GO:0009611]; transcytosis [GO:0045056]		astrocyte activation [GO:0048143]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; glucose mediated signaling pathway [GO:0010255]; induction of positive chemotaxis [GO:0050930]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of blood circulation [GO:1903523]; negative regulation of connective tissue replacement involved in inflammatory response wound healing [GO:1904597]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of long-term synaptic depression [GO:1900453]; negative regulation of long-term synaptic potentiation [GO:1900272]; neuron projection development [GO:0031175]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of monocyte extravasation [GO:2000439]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein localization to membrane [GO:0072657]; regulation of CD4-positive, alpha-beta T cell activation [GO:2000514]; regulation of DNA binding [GO:0051101]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of p38MAPK cascade [GO:1900744]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell mediated cytotoxicity [GO:0001914]; response to amyloid-beta [GO:1904645]; response to hypoxia [GO:0001666]; response to wounding [GO:0009611]; transcytosis [GO:0045056]	myosin complex [GO:0016459]	apical plasma membrane [GO:0016324]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; extracellular region [GO:0005576]; fibrillar center [GO:0001650]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	advanced glycation end-product receptor activity [GO:0050785]; amyloid-beta binding [GO:0001540]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; S100 protein binding [GO:0044548]; scavenger receptor activity [GO:0005044]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]
d3ts5e__d2rrta1__1	Metazoa	Metazoa	Mollusca	Chordata	myosin complex [GO:0016459]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]; calcium-mediated signaling [GO:0019722]		calcium-mediated signaling [GO:0019722]	myosin complex [GO:0016459]		actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	calcium ion binding [GO:0005509]; signaling receptor binding [GO:0005102]
d3tsca__d3pduc1__1			Actinobacteria	Proteobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]					nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]
d3tska1_d3q7ja2__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; metallopeptidase activity [GO:0008237]; zinc ion binding [GO:0008270]
d3tsrf1_d4peqd___1	Metazoa	Metazoa	Chordata	Chordata	angiogenin-PRI complex [GO:0032311]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; ribonuclease inhibitor activity [GO:0008428]; regulation of angiogenesis [GO:0045765]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	regulation of angiogenesis [GO:0045765]		angiogenin-PRI complex [GO:0032311]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	extracellular region [GO:0005576]	ribonuclease inhibitor activity [GO:0008428]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d3tsva__d2kawa___1	Metazoa	Metazoa	Chordata	Chordata	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell junction [GO:0030054]; cell projection [GO:0042995]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; Rac GTPase binding [GO:0048365]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; collateral sprouting [GO:0048668]; convergent extension involved in neural plate elongation [GO:0022007]; convergent extension involved in organogenesis [GO:0060029]; cytoplasmic microtubule organization [GO:0031122]; dendrite morphogenesis [GO:0048813]; dendritic spine morphogenesis [GO:0060997]; intracellular signal transduction [GO:0035556]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse organization [GO:0099173]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein localization to microtubule [GO:0035372]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cellular protein localization [GO:1903827]; regulation of neurotransmitter levels [GO:0001505]; regulation of protein phosphorylation [GO:0001932]; regulation of synaptic vesicle exocytosis [GO:2000300]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; social behavior [GO:0035176]; synapse organization [GO:0050808]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	adherens junction maintenance [GO:0034334]; cell-cell junction assembly [GO:0007043]; cell-cell junction organization [GO:0045216]; cell-cell signaling involved in cell-cell junction organization [GO:1901350]; establishment of endothelial intestinal barrier [GO:0090557]; hippo signaling [GO:0035329]; negative regulation of actin cytoskeleton reorganization [GO:2000250]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of cell migration [GO:0030335]; positive regulation of maintenance of permeability of blood-brain barrier [GO:1905605]; positive regulation of sprouting angiogenesis [GO:1903672]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell-cell junction [GO:0150105]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytoskeleton organization [GO:0051493]	axon extension [GO:0048675]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; collateral sprouting [GO:0048668]; convergent extension involved in neural plate elongation [GO:0022007]; convergent extension involved in organogenesis [GO:0060029]; cytoplasmic microtubule organization [GO:0031122]; dendrite morphogenesis [GO:0048813]; dendritic spine morphogenesis [GO:0060997]; intracellular signal transduction [GO:0035556]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse organization [GO:0099173]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein localization to microtubule [GO:0035372]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cellular protein localization [GO:1903827]; regulation of neurotransmitter levels [GO:0001505]; regulation of protein phosphorylation [GO:0001932]; regulation of synaptic vesicle exocytosis [GO:2000300]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; social behavior [GO:0035176]; synapse organization [GO:0050808]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell-cell adherens junction [GO:0005913]; cell junction [GO:0030054]; cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; gap junction [GO:0005921]; plasma membrane [GO:0005886]; podosome [GO:0002102]; tight junction [GO:0070160]	axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]	cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]	beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; Rac GTPase binding [GO:0048365]
d3tsxc__d3kicf___1						viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d3tsxs__d3ng9f___1						viral capsid [GO:0019028]; structural molecule activity [GO:0005198]				viral capsid [GO:0019028]		structural molecule activity [GO:0005198]
d3tt1l1_d1fv1b1__1		Metazoa	Aquificae	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; neurotransmitter:sodium symporter activity [GO:0005328]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]		adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	neurotransmitter:sodium symporter activity [GO:0005328]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d3tt1l2_d1mvub___1		Metazoa	Aquificae	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; neurotransmitter:sodium symporter activity [GO:0005328]	apical plasma membrane [GO:0016324]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; ATPase-coupled xenobiotic transmembrane transporter activity [GO:0008559]; ceramide floppase activity [GO:0099038]; efflux transmembrane transporter activity [GO:0015562]; floppase activity [GO:0140328]; phosphatidylcholine floppase activity [GO:0090554]; phosphatidylethanolamine flippase activity [GO:0090555]; xenobiotic transmembrane transporter activity [GO:0042910]; phospholipid translocation [GO:0045332]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transport across blood-brain barrier [GO:1990962]		phospholipid translocation [GO:0045332]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transport across blood-brain barrier [GO:1990962]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]	neurotransmitter:sodium symporter activity [GO:0005328]	ATPase activity, coupled [GO:0042623]; ATPase-coupled xenobiotic transmembrane transporter activity [GO:0008559]; ATP binding [GO:0005524]; ceramide floppase activity [GO:0099038]; efflux transmembrane transporter activity [GO:0015562]; floppase activity [GO:0140328]; phosphatidylcholine floppase activity [GO:0090554]; phosphatidylethanolamine flippase activity [GO:0090555]; xenobiotic transmembrane transporter activity [GO:0042910]
d3tt1m1_d2eytc1__1		Metazoa	Aquificae	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; neurotransmitter:sodium symporter activity [GO:0005328]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	neurotransmitter:sodium symporter activity [GO:0005328]	
d3tt4a__d1os2c1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3ttaa__d2we0a1__1					viral nucleocapsid [GO:0019013]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]; nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	nucleotide metabolic process [GO:0009117]; viral process [GO:0016032]	dUTP metabolic process [GO:0046080]	viral nucleocapsid [GO:0019013]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]
d3ttea2_d2ps2d2__1		Fungi	Proteobacteria	Ascomycota	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]	metal ion binding [GO:0046872]	cellular amino acid catabolic process [GO:0009063]				mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]	metal ion binding [GO:0046872]
d3tteb2_d2bahc2__1			Proteobacteria		mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]; cellular amino acid catabolic process [GO:0009063]		cellular amino acid catabolic process [GO:0009063]				mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; muconate cycloisomerase activity [GO:0018849]	
d3ttkb__d5dtbb___1		Metazoa	Proteobacteria	Arthropoda	periplasmic space [GO:0042597]; putrescine binding [GO:0019810]; polyamine transport [GO:0015846]	cell [GO:0005623]; cell junction [GO:0030054]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic active zone [GO:0048786]; glutamate receptor activity [GO:0008066]; glutamate-gated calcium ion channel activity [GO:0022849]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; calcium ion import across plasma membrane [GO:0098703]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of neuromuscular synaptic transmission [GO:1900075]; regulation of synaptic activity [GO:0060025]; synaptic transmission, glutamatergic [GO:0035249]	polyamine transport [GO:0015846]	calcium ion import across plasma membrane [GO:0098703]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of neuromuscular synaptic transmission [GO:1900075]; regulation of synaptic activity [GO:0060025]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]	cell [GO:0005623]; cell junction [GO:0030054]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic active zone [GO:0048786]	putrescine binding [GO:0019810]	glutamate-gated calcium ion channel activity [GO:0022849]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3ttkc__d5lomb1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; putrescine binding [GO:0019810]; polyamine transport [GO:0015846]	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	polyamine transport [GO:0015846]		periplasmic space [GO:0042597]	membrane [GO:0016020]	putrescine binding [GO:0019810]	ligand-gated ion channel activity [GO:0015276]
d3ttlb__d1ms7b___1		Metazoa	Proteobacteria	Chordata	extracellular space [GO:0005615]; periplasmic space [GO:0042597]; spermidine binding [GO:0019809]; pathogenesis [GO:0009405]; polyamine transport [GO:0015846]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	pathogenesis [GO:0009405]; polyamine transport [GO:0015846]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	extracellular space [GO:0005615]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	spermidine binding [GO:0019809]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3ttpa__d5p58a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3ttta2_d5tw7f1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; pyrophosphatase activity [GO:0016462]; glutamine metabolic process [GO:0006541]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	glutamine metabolic process [GO:0006541]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; pyrophosphatase activity [GO:0016462]
d3tttd2_d4lrua1__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	fungal biofilm matrix [GO:0062040]; hyphal cell wall [GO:0030446]; yeast-form cell wall [GO:0030445]; glyoxalase III activity [GO:0019172]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	fungal biofilm matrix [GO:0062040]; hyphal cell wall [GO:0030446]; yeast-form cell wall [GO:0030445]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	glyoxalase III activity [GO:0019172]
d3ttuc2_d1rw7a___1			Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]		cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	
d3tu2a1_d2oneb2__1		Fungi		Ascomycota		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3tu2a2_d2gl5a1__1				Proteobacteria		metal ion binding [GO:0046872]						metal ion binding [GO:0046872]
d3tu5b1_d1c0gs___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; barbed-end actin filament capping [GO:0051016]; cellular protein metabolic process [GO:0044267]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; neutrophil degranulation [GO:0043312]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; blood microparticle [GO:0072562]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; secretory granule lumen [GO:0034774]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]
d3tu5b1_d1hqz8___1	Metazoa	Fungi	Chordata	Ascomycota	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]; actin filament binding [GO:0051015]; actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein localization to actin cortical patch [GO:0044379]; regulation of actin filament polymerization [GO:0030833]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin cortical patch [GO:0030479]; cell cortex [GO:0005938]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; mating projection tip [GO:0043332]; plasma membrane [GO:0005886]; site of polarized growth [GO:0030427]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	actin filament binding [GO:0051015]
d3tuid2_d2bj9a2__1			Proteobacteria	Euryarchaeota	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; L-methionine transmembrane transporter activity [GO:0015191]; D-methionine transport [GO:0048473]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nickel cation binding [GO:0016151]; response to nickel cation [GO:0010045]	D-methionine transport [GO:0048473]	response to nickel cation [GO:0010045]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		L-methionine transmembrane transporter activity [GO:0015191]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; nickel cation binding [GO:0016151]
d3tuid2_d3qsii___1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; L-methionine transmembrane transporter activity [GO:0015191]; D-methionine transport [GO:0048473]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	D-methionine transport [GO:0048473]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	protein-DNA complex [GO:0032993]	L-methionine transmembrane transporter activity [GO:0015191]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3tuih2_d3lgha2__1			Proteobacteria	Proteobacteria	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; L-methionine transmembrane transporter activity [GO:0015191]; D-methionine transport [GO:0048473]	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	D-methionine transport [GO:0048473]	negative regulation of transcription, DNA-templated [GO:0045892]; response to nickel cation [GO:0010045]	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	protein-DNA complex [GO:0032993]	L-methionine transmembrane transporter activity [GO:0015191]	DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; nickel cation binding [GO:0016151]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3tuyb__d3cztx___1	Metazoa	Metazoa	Mollusca	Chordata	myosin complex [GO:0016459]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]; astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]		astrocyte differentiation [GO:0048708]; axonogenesis [GO:0007409]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of myelination [GO:0031643]; regulation of cell shape [GO:0008360]; regulation of neuronal synaptic plasticity [GO:0048168]; response to glucocorticoid [GO:0051384]; response to methylmercury [GO:0051597]	myosin complex [GO:0016459]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ruffle [GO:0001726]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RAGE receptor binding [GO:0050786]; S100 protein binding [GO:0044548]; tau protein binding [GO:0048156]; zinc ion binding [GO:0008270]
d3tuyc__d2k7da___1	Metazoa	Metazoa	Mollusca	Chordata	myosin complex [GO:0016459]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	cell cortex [GO:0005938]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; enzyme inhibitor activity [GO:0004857]; nuclear localization sequence binding [GO:0008139]; negative regulation of protein import into nucleus [GO:0042308]; response to stimulus [GO:0050896]; visual perception [GO:0007601]		negative regulation of protein import into nucleus [GO:0042308]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	myosin complex [GO:0016459]	cell cortex [GO:0005938]; cell junction [GO:0030054]; cytoskeleton [GO:0005856]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; enzyme inhibitor activity [GO:0004857]; nuclear localization sequence binding [GO:0008139]
d3tv5b1_d1wdla4__1	Fungi		Ascomycota	Proteobacteria	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	fatty acid beta-oxidation multienzyme complex [GO:0036125]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]; fatty acid beta-oxidation [GO:0006635]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	fatty acid beta-oxidation [GO:0006635]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	fatty acid beta-oxidation multienzyme complex [GO:0036125]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA epimerase activity [GO:0008692]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; enoyl-CoA hydratase activity [GO:0004300]
d3tv8b1_d3baja2__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3tvca__d2woad___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d3tvmh1_d5tq0l2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell [GO:0005623]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; neuron projection [GO:0043005]; NMDA selective glutamate receptor complex [GO:0017146]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; ATPase binding [GO:0051117]; cell adhesion molecule binding [GO:0050839]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; glutamate receptor binding [GO:0035254]; glutamate-gated calcium ion channel activity [GO:0022849]; ionotropic glutamate receptor activity [GO:0004970]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; zinc ion binding [GO:0008270]; action potential [GO:0001508]; calcium ion transmembrane import into cytosol [GO:0097553]; cellular response to amino acid stimulus [GO:0071230]; cellular response to dsRNA [GO:0071359]; cellular response to growth factor stimulus [GO:0071363]; cellular response to lipid [GO:0071396]; cellular response to magnesium ion [GO:0071286]; cellular response to manganese ion [GO:0071287]; cellular response to zinc ion [GO:0071294]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; dendritic spine organization [GO:0097061]; excitatory postsynaptic potential [GO:0060079]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of cell death [GO:0010942]; positive regulation of excitatory postsynaptic potential [GO:2000463]; protein tetramerization [GO:0051262]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; response to amine [GO:0014075]; response to ammonium ion [GO:0060359]; response to calcium ion [GO:0051592]; response to carbohydrate [GO:0009743]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to fungicide [GO:0060992]; response to light stimulus [GO:0009416]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to organic cyclic compound [GO:0014070]; response to other organism [GO:0051707]; rhythmic process [GO:0048511]; spinal cord development [GO:0021510]; synaptic transmission, glutamatergic [GO:0035249]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	action potential [GO:0001508]; calcium ion transmembrane import into cytosol [GO:0097553]; cellular response to amino acid stimulus [GO:0071230]; cellular response to dsRNA [GO:0071359]; cellular response to growth factor stimulus [GO:0071363]; cellular response to lipid [GO:0071396]; cellular response to magnesium ion [GO:0071286]; cellular response to manganese ion [GO:0071287]; cellular response to zinc ion [GO:0071294]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; dendritic spine organization [GO:0097061]; excitatory postsynaptic potential [GO:0060079]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of cell death [GO:0010942]; positive regulation of excitatory postsynaptic potential [GO:2000463]; protein tetramerization [GO:0051262]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of NMDA receptor activity [GO:2000310]; response to amine [GO:0014075]; response to ammonium ion [GO:0060359]; response to calcium ion [GO:0051592]; response to carbohydrate [GO:0009743]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to fungicide [GO:0060992]; response to light stimulus [GO:0009416]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to organic cyclic compound [GO:0014070]; response to other organism [GO:0051707]; rhythmic process [GO:0048511]; spinal cord development [GO:0021510]; synaptic transmission, glutamatergic [GO:0035249]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cell [GO:0005623]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; neuron projection [GO:0043005]; NMDA selective glutamate receptor complex [GO:0017146]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]		ATPase binding [GO:0051117]; cell adhesion molecule binding [GO:0050839]; glutamate binding [GO:0016595]; glutamate-gated calcium ion channel activity [GO:0022849]; glutamate receptor activity [GO:0008066]; glutamate receptor binding [GO:0035254]; ionotropic glutamate receptor activity [GO:0004970]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; neurotransmitter binding [GO:0042165]; NMDA glutamate receptor activity [GO:0004972]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; zinc ion binding [GO:0008270]
d3tvmh2_d1pywa1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d3tvnx__d4xz5a___1	Metazoa		Chordata	Proteobacteria	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]		apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]		arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3tvox__d3oysa___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3tvub1_d1o8ub___1	Fungi		Ascomycota	Actinobacteria	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]		acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]		acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [GO:0016823]
d3tvwa1_d3h0qc1__1	Fungi	Fungi	Ascomycota	Ascomycota	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d3tvwa1_d4q1kb___1	Fungi		Ascomycota	Firmicutes	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	cytoplasm [GO:0005737]; enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]; antibiotic biosynthetic process [GO:0017000]; fatty acid beta-oxidation [GO:0006635]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	antibiotic biosynthetic process [GO:0017000]; fatty acid beta-oxidation [GO:0006635]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	enoyl-CoA hydratase activity [GO:0004300]; isomerase activity [GO:0016853]
d3tvxa1_d2y0ja___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of protein kinase A signaling [GO:0010738]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of protein kinase A signaling [GO:0010738]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3tw2a__d5in3a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; UDP-glucose catabolic process [GO:0006258]; UDP-glucose metabolic process [GO:0006011]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; UDP-glucose catabolic process [GO:0006258]; UDP-glucose metabolic process [GO:0006011]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]	hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]	UDP-glucose:hexose-1-phosphate uridylyltransferase activity [GO:0008108]; zinc ion binding [GO:0008270]
d3tw2b__d3p0tb1__1	Metazoa		Chordata	Actinobacteria	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	catalytic activity [GO:0003824]	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]		cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		hydrolase activity [GO:0016787]; nucleotide binding [GO:0000166]; protein kinase C binding [GO:0005080]	catalytic activity [GO:0003824]
d3twaa1_d3q45b1__1			Proteobacteria	Bacteroidetes	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; peptide metabolic process [GO:0006518]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	peptide metabolic process [GO:0006518]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; racemase and epimerase activity [GO:0016854]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d3twaa2_d3fyyb2__1			Proteobacteria	Firmicutes	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]				gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]
d3twab2_d4fp1a2__1			Proteobacteria	Proteobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d3twac1_d3enla2__1		Fungi	Proteobacteria	Ascomycota	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3twac2_d1xpyb1__1			Proteobacteria	Deinococcus-Thermus	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	menaquinone biosynthetic process [GO:0009234]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3twac2_d3p0wd2__1			Proteobacteria	Proteobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]		carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]				gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	
d3twad1_d3pwia1__1			Proteobacteria	Proteobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	D-glucarate catabolic process [GO:0042838]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3twad2_d2dw7p1__1			Proteobacteria	Proteobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	protein homooligomerization [GO:0051260]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]
d3twae2_d3es8e2__1			Proteobacteria	Firmicutes	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]				gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]
d3twba1_d2xh2c1__1		Fungi	Proteobacteria	Ascomycota	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3twba2_d1mucb1__1			Proteobacteria	Proteobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; beta-ketoadipate pathway [GO:0042952]; cellular amino acid catabolic process [GO:0009063]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	beta-ketoadipate pathway [GO:0042952]; cellular amino acid catabolic process [GO:0009063]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d3twba2_d3uj2d2__1			Proteobacteria	Firmicutes	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	glycolytic process [GO:0006096]		cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3twbb1_d1sjad2__1			Proteobacteria	Actinobacteria	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	menaquinone biosynthetic process [GO:0009234]			gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3twbe1_d3otrf1__1			Proteobacteria	Apicomplexa	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	glycolytic process [GO:0006096]		phosphopyruvate hydratase complex [GO:0000015]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3twid__d4krmc1__1		Metazoa	Firmicutes	Chordata	regulation of phagocytosis [GO:0050764]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	regulation of phagocytosis [GO:0050764]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]		apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]		actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d3twqb1_d1awcb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription regulatory region DNA binding [GO:0044212]; blastocyst formation [GO:0001825]; cell differentiation [GO:0030154]; cellular response to dopamine [GO:1903351]; in utero embryonic development [GO:0001701]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	blastocyst formation [GO:0001825]; cell differentiation [GO:0030154]; cellular response to dopamine [GO:1903351]; in utero embryonic development [GO:0001701]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]	activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription regulatory region DNA binding [GO:0044212]
d3twra__d1wg0a2__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; nucleus [GO:0005634]; proteasome regulatory particle binding [GO:1904855]; proteasome regulatory particle assembly [GO:0070682]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	proteasome regulatory particle assembly [GO:0070682]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	cytosol [GO:0005829]; nucleus [GO:0005634]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]	proteasome regulatory particle binding [GO:1904855]
d3twrc__d1g3nb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]; astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	astrocyte development [GO:0014002]; cell cycle arrest [GO:0007050]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; dentate gyrus development [GO:0021542]; G1/S transition of mitotic cell cycle [GO:0000082]; generation of neurons [GO:0048699]; gliogenesis [GO:0042063]; hematopoietic stem cell differentiation [GO:0060218]; lateral ventricle development [GO:0021670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	centrosome [GO:0005813]; cyclin D2-CDK6 complex [GO:0097132]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ruffle [GO:0001726]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; FBXO family protein binding [GO:0098770]
d3twrd1_d1nfif___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3twsd__d3d9ha___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; intracellular signal transduction [GO:0035556]; positive regulation of protein catabolic process [GO:0045732]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	intracellular signal transduction [GO:0035556]; positive regulation of protein catabolic process [GO:0045732]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	cytosol [GO:0005829]; mitochondrion [GO:0005739]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]	
d3twta__d4a63h1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3twtc1_d4k5ca___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]		multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]		enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]	
d3twtd1_d1mx2b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]; cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of phosphorylation [GO:0042326]; oligodendrocyte differentiation [GO:0048709]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of phosphorylation [GO:0042326]; oligodendrocyte differentiation [GO:0048709]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]	cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; protein kinase binding [GO:0019901]
d3twwa__d2kxpc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; F-actin capping protein complex [GO:0008290]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; sequence-specific DNA binding [GO:0043565]; catecholamine metabolic process [GO:0006584]; cellular response to mechanical stimulus [GO:0071260]; cerebellar granule cell differentiation [GO:0021707]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell growth [GO:0030307]; positive regulation of macromolecule biosynthetic process [GO:0010557]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein metabolic process [GO:0051247]; regulation of barbed-end actin filament capping [GO:2000812]; regulation of cell size [GO:0008361]; skeletal muscle tissue regeneration [GO:0043403]; striated muscle cell differentiation [GO:0051146]	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	catecholamine metabolic process [GO:0006584]; cellular response to mechanical stimulus [GO:0071260]; cerebellar granule cell differentiation [GO:0021707]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell growth [GO:0030307]; positive regulation of macromolecule biosynthetic process [GO:0010557]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein metabolic process [GO:0051247]; regulation of barbed-end actin filament capping [GO:2000812]; regulation of cell size [GO:0008361]; skeletal muscle tissue regeneration [GO:0043403]; striated muscle cell differentiation [GO:0051146]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]	axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; F-actin capping protein complex [GO:0008290]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]	sequence-specific DNA binding [GO:0043565]
d3twwb1_d4hlla___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]; enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]		multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; nuclear chromosome, telomeric region [GO:0000784]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; pericentriolar material [GO:0000242]; perinuclear region of cytoplasm [GO:0048471]		enzyme binding [GO:0019899]; metal ion binding [GO:0046872]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; protein ADP-ribosylase activity [GO:1990404]	
d3txba__d152la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3txea__d181la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3txga__d1p46a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3txha__d1l23a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3txia__d1d9ua___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lyase activity [GO:0016829]; lysozyme activity [GO:0003796]; lytic transglycosylase activity [GO:0008933]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lyase activity [GO:0016829]; lysozyme activity [GO:0003796]; lytic transglycosylase activity [GO:0008933]
d3txja__d2b6ya___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3txka__d145la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3ty4a__d1idea___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; homoisocitrate dehydrogenase activity [GO:0047046]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; lysine biosynthetic process [GO:0009085]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	lysine biosynthetic process [GO:0009085]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	homoisocitrate dehydrogenase activity [GO:0047046]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d3ty6a__d4fzgm___1		Fungi	Firmicutes	Ascomycota	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3ty6c__d1z7qk1__1		Fungi	Firmicutes	Ascomycota	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]; metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]; proteolysis involved in cellular protein catabolic process [GO:0051603]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteolysis involved in cellular protein catabolic process [GO:0051603]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; proteasome core complex [GO:0005839]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	metal ion binding [GO:0046872]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3tyfa1_d1h3va2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3tyfb2_d4nm4l1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3tyfd2_d5ebmb1__1				Actinobacteria		voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]				voltage-gated potassium channel complex [GO:0008076]		identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d3tyha__d4pfwa___1			Proteobacteria	Thermotogae	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; metal ion binding [GO:0046872]; transmembrane transport [GO:0055085]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	transmembrane transport [GO:0055085]	periplasmic space [GO:0042597]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3tyhf__d2ghba___1			Proteobacteria	Thermotogae	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	proteasome core complex, alpha-subunit complex [GO:0019773]; carbohydrate transmembrane transporter activity [GO:0015144]; endopeptidase activity [GO:0004175]; ubiquitin-dependent protein catabolic process [GO:0006511]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	ubiquitin-dependent protein catabolic process [GO:0006511]	periplasmic space [GO:0042597]	proteasome core complex, alpha-subunit complex [GO:0019773]	metal ion binding [GO:0046872]	carbohydrate transmembrane transporter activity [GO:0015144]; endopeptidase activity [GO:0004175]
d3tyhg__d4bdlb___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; transmembrane transport [GO:0055085]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d3tz0a1_d2bu7a1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrion [GO:0005739]; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity [GO:0047323]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740]; cellular response to nutrient [GO:0031670]; cellular response to reactive oxygen species [GO:0034614]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]	branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	cellular response to nutrient [GO:0031670]; cellular response to reactive oxygen species [GO:0034614]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrial pyruvate dehydrogenase complex [GO:0005967]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity [GO:0047323]; ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO:0004740]
d3tz3b1_d1k39a___1	Fungi	Fungi	Ascomycota	Ascomycota	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; dodecenoyl-CoA delta-isomerase activity [GO:0004165]; fatty acid beta-oxidation [GO:0006635]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	fatty acid beta-oxidation [GO:0006635]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	dodecenoyl-CoA delta-isomerase activity [GO:0004165]
d3tz3c1_d1xnyb2__1	Fungi		Ascomycota	Actinobacteria	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	acetyl-CoA carboxylase complex [GO:0009317]; acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]; fatty acid biosynthetic process [GO:0006633]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	fatty acid biosynthetic process [GO:0006633]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	acetyl-CoA carboxylase complex [GO:0009317]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]	acetyl-CoA carboxylase activity [GO:0003989]; transferase activity [GO:0016740]
d3tzbd__d5eaia___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3tzhb__d3tscd___1				Actinobacteria		nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]						nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3tzhb__d4ixwb___1				Proteobacteria								
d3tzkb__d4iiub___1				Proteobacteria		3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; nucleotide binding [GO:0000166]						3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; nucleotide binding [GO:0000166]
d3tzoa1_d4duaa___1			Actinobacteria	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]			cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d3tzob1_d5l90b1__1			Actinobacteria	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	oxidation-reduction process [GO:0055114]; pigment metabolic process [GO:0042440]				heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3tzqd__d3wyea___1			Actinobacteria	Actinobacteria		(S,S)-butanediol dehydrogenase activity [GO:0047512]; diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]; acetoin catabolic process [GO:0045150]; acetoin metabolic process [GO:0045149]; butanediol metabolic process [GO:0034077]; protein homotetramerization [GO:0051289]		acetoin catabolic process [GO:0045150]; acetoin metabolic process [GO:0045149]; butanediol metabolic process [GO:0034077]; protein homotetramerization [GO:0051289]				(S,S)-butanediol dehydrogenase activity [GO:0047512]; diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]
d3tzqe__d1up7f1__1			Actinobacteria	Thermotogae		6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3tzsb__d1mx7a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cell body [GO:0044297]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]; all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinol binding [GO:0019841]; lipid homeostasis [GO:0055088]; regulation of granulocyte differentiation [GO:0030852]; response to vitamin A [GO:0033189]; retinoic acid biosynthetic process [GO:0002138]; retinol metabolic process [GO:0042572]; vitamin A metabolic process [GO:0006776]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	lipid homeostasis [GO:0055088]; regulation of granulocyte differentiation [GO:0030852]; response to vitamin A [GO:0033189]; retinoic acid biosynthetic process [GO:0002138]; retinol metabolic process [GO:0042572]; vitamin A metabolic process [GO:0006776]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cell body [GO:0044297]; cytosol [GO:0005829]; lipid droplet [GO:0005811]; nucleoplasm [GO:0005654]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	all-trans-retinol binding [GO:1904768]; retinal binding [GO:0016918]; retinol binding [GO:0019841]
d3tzuc__d2dnca1__1		Metazoa	Actinobacteria	Chordata	glycine cleavage complex [GO:0005960]; glycine decarboxylation via glycine cleavage system [GO:0019464]	mitochondrial matrix [GO:0005759]; pyruvate dehydrogenase complex [GO:0045254]; transferase activity, transferring acyl groups [GO:0016746]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]	glycine decarboxylation via glycine cleavage system [GO:0019464]	mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]	glycine cleavage complex [GO:0005960]	mitochondrial matrix [GO:0005759]; pyruvate dehydrogenase complex [GO:0045254]		transferase activity, transferring acyl groups [GO:0016746]
d3tzvb2_d5v4mj2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d3tzvh2_d1zt7b1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3u00a__d4owza___1	Metazoa	Metazoa	Chordata	Chordata	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]	azurophil granule lumen [GO:0035578]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; endonuclease activity [GO:0004519]; lipopolysaccharide binding [GO:0001530]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]; antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; neutrophil degranulation [GO:0043312]; RNA catabolic process [GO:0006401]		antibacterial humoral response [GO:0019731]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; neutrophil degranulation [GO:0043312]; RNA catabolic process [GO:0006401]		azurophil granule lumen [GO:0035578]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endonuclease activity [GO:0004519]; nucleic acid binding [GO:0003676]	endonuclease activity [GO:0004519]; lipopolysaccharide binding [GO:0001530]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d3u03a__d1yp6a1__1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone activity [GO:0005186]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to food [GO:0071240]; cellular response to lipid [GO:0071396]; cellular response to starvation [GO:0009267]; cellular response to testosterone stimulus [GO:0071394]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]; response to stilbenoid [GO:0035634]		aerobic respiration [GO:0009060]; cellular response to food [GO:0071240]; cellular response to lipid [GO:0071396]; cellular response to starvation [GO:0009267]; cellular response to testosterone stimulus [GO:0071394]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]; response to stilbenoid [GO:0035634]		cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		insulin-activated receptor activity [GO:0005009]; pheromone activity [GO:0005186]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]
d3u09b1_d1mldb1__1		Metazoa	Proteobacteria	Chordata	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; chaperone binding [GO:0051087]; L-malate dehydrogenase activity [GO:0030060]; protein homodimerization activity [GO:0042803]; aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]	aerobic respiration [GO:0009060]; carbohydrate metabolic process [GO:0005975]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	chaperone binding [GO:0051087]; L-malate dehydrogenase activity [GO:0030060]; protein homodimerization activity [GO:0042803]
d3u0da__d4qgvb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3u0db__d2wqae___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3u0db__d4ygza___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3u0dd__d3pp6a___1	Metazoa	Metazoa	Chordata	Mollusca	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	cytoplasm [GO:0005737]; membrane [GO:0016020]; lipid binding [GO:0008289]	antimicrobial humoral response [GO:0019730]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; neutrophil degranulation [GO:0043312]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]	cytoplasm [GO:0005737]; membrane [GO:0016020]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	lipid binding [GO:0008289]
d3u0ea2_d1m1od2__1			Proteobacteria	Proteobacteria	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]		poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3u0pa1_d3o8xa1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3u0pa2_d3wjlb1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3u0pb__d2fjfc1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3u0pc2_d1wiqa3__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3u0wl1_d5wawl2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3u0ya1_d4ho9b___1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	extracellular polysaccharide biosynthetic process [GO:0045226]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]		antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d3u0yb__d3srza___1	Metazoa		Chordata	Firmicutes	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	transferase activity, transferring glycosyl groups [GO:0016757]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]		antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]	transferase activity, transferring glycosyl groups [GO:0016757]
d3u0za__d2bgcd2__1	Metazoa		Chordata	Firmicutes	apical dendrite [GO:0097440]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein C-terminus binding [GO:0008022]; protein-containing complex binding [GO:0044877]; voltage-gated cation channel activity [GO:0022843]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]; apical protein localization [GO:0045176]; cellular response to cAMP [GO:0071320]; negative regulation of action potential [GO:0045759]; positive regulation of cation channel activity [GO:2001259]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; regulation of membrane depolarization [GO:0003254]; regulation of membrane hyperpolarization [GO:1902630]; regulation of membrane potential [GO:0042391]; response to calcium ion [GO:0051592]; retinal cone cell development [GO:0046549]; sodium ion transmembrane transport [GO:0035725]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; pathogenesis [GO:0009405]	apical protein localization [GO:0045176]; cellular response to cAMP [GO:0071320]; negative regulation of action potential [GO:0045759]; positive regulation of cation channel activity [GO:2001259]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; regulation of membrane depolarization [GO:0003254]; regulation of membrane hyperpolarization [GO:1902630]; regulation of membrane potential [GO:0042391]; response to calcium ion [GO:0051592]; retinal cone cell development [GO:0046549]; sodium ion transmembrane transport [GO:0035725]	pathogenesis [GO:0009405]	apical dendrite [GO:0097440]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]		cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; voltage-gated cation channel activity [GO:0022843]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3u0za__d3e6da1__1	Metazoa		Chordata	Firmicutes	apical dendrite [GO:0097440]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein C-terminus binding [GO:0008022]; protein-containing complex binding [GO:0044877]; voltage-gated cation channel activity [GO:0022843]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]; apical protein localization [GO:0045176]; cellular response to cAMP [GO:0071320]; negative regulation of action potential [GO:0045759]; positive regulation of cation channel activity [GO:2001259]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; regulation of membrane depolarization [GO:0003254]; regulation of membrane hyperpolarization [GO:1902630]; regulation of membrane potential [GO:0042391]; response to calcium ion [GO:0051592]; retinal cone cell development [GO:0046549]; sodium ion transmembrane transport [GO:0035725]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	apical protein localization [GO:0045176]; cellular response to cAMP [GO:0071320]; negative regulation of action potential [GO:0045759]; positive regulation of cation channel activity [GO:2001259]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; regulation of membrane depolarization [GO:0003254]; regulation of membrane hyperpolarization [GO:1902630]; regulation of membrane potential [GO:0042391]; response to calcium ion [GO:0051592]; retinal cone cell development [GO:0046549]; sodium ion transmembrane transport [GO:0035725]	regulation of transcription, DNA-templated [GO:0006355]	apical dendrite [GO:0097440]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]		cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; voltage-gated cation channel activity [GO:0022843]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]	DNA binding [GO:0003677]
d3u0zb__d5t3nb1__1	Metazoa		Chordata	Apicomplexa	apical dendrite [GO:0097440]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein C-terminus binding [GO:0008022]; protein-containing complex binding [GO:0044877]; voltage-gated cation channel activity [GO:0022843]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]; apical protein localization [GO:0045176]; cellular response to cAMP [GO:0071320]; negative regulation of action potential [GO:0045759]; positive regulation of cation channel activity [GO:2001259]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; regulation of membrane depolarization [GO:0003254]; regulation of membrane hyperpolarization [GO:1902630]; regulation of membrane potential [GO:0042391]; response to calcium ion [GO:0051592]; retinal cone cell development [GO:0046549]; sodium ion transmembrane transport [GO:0035725]	cAMP-dependent protein kinase complex [GO:0005952]; cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP-dependent protein kinase activity [GO:0004691]; cAMP-dependent protein kinase regulator activity [GO:0008603]; nucleotide binding [GO:0000166]; cGMP-mediated signaling [GO:0019934]	apical protein localization [GO:0045176]; cellular response to cAMP [GO:0071320]; negative regulation of action potential [GO:0045759]; positive regulation of cation channel activity [GO:2001259]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; regulation of membrane depolarization [GO:0003254]; regulation of membrane hyperpolarization [GO:1902630]; regulation of membrane potential [GO:0042391]; response to calcium ion [GO:0051592]; retinal cone cell development [GO:0046549]; sodium ion transmembrane transport [GO:0035725]	cGMP-mediated signaling [GO:0019934]	apical dendrite [GO:0097440]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]	cAMP-dependent protein kinase complex [GO:0005952]; cytosol [GO:0005829]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein-containing complex binding [GO:0044877]; protein C-terminus binding [GO:0008022]; voltage-gated cation channel activity [GO:0022843]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP-dependent protein kinase activity [GO:0004691]; cAMP-dependent protein kinase regulator activity [GO:0008603]; nucleotide binding [GO:0000166]
d3u1ea2_d1li7b1__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; cysteine-tRNA ligase activity [GO:0004817]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cysteinyl-tRNA aminoacylation [GO:0006423]		cysteinyl-tRNA aminoacylation [GO:0006423]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		aminoacyl-tRNA ligase activity [GO:0004812]; ATP binding [GO:0005524]; cysteine-tRNA ligase activity [GO:0004817]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d3u1fa2_d1pfua1__1				Proteobacteria		cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; methionyl-tRNA aminoacylation [GO:0006431]		methionyl-tRNA aminoacylation [GO:0006431]		cytosol [GO:0005829]; membrane [GO:0016020]		ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d3u1ga2_d1pg0a1__1				Proteobacteria		cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; methionyl-tRNA aminoacylation [GO:0006431]		methionyl-tRNA aminoacylation [GO:0006431]		cytosol [GO:0005829]; membrane [GO:0016020]		ATP binding [GO:0005524]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d3u1jb__d4wh8b1__1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3u1ma2_d4uqta___1	Fungi	Fungi	Ascomycota	Ascomycota	Prp19 complex [GO:0000974]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]; metal ion binding [GO:0046872]; pre-mRNA binding [GO:0036002]; U6 snRNA binding [GO:0017070]; cell cycle [GO:0007049]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cell cycle [GO:0045787]; positive regulation of RNA splicing [GO:0033120]; spliceosomal snRNP assembly [GO:0000387]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; RES complex [GO:0070274]; U2-type spliceosomal complex [GO:0005684]; mRNA splicing, via spliceosome [GO:0000398]	cell cycle [GO:0007049]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cell cycle [GO:0045787]; positive regulation of RNA splicing [GO:0033120]; spliceosomal snRNP assembly [GO:0000387]	mRNA splicing, via spliceosome [GO:0000398]	Prp19 complex [GO:0000974]; U2-type catalytic step 1 spliceosome [GO:0071006]; U2-type catalytic step 2 spliceosome [GO:0071007]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; RES complex [GO:0070274]; U2-type spliceosomal complex [GO:0005684]	metal ion binding [GO:0046872]; pre-mRNA binding [GO:0036002]; U6 snRNA binding [GO:0017070]	
d3u1ra2_d5d7wa2__1			Bacteroidetes	Proteobacteria	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; pathogenesis [GO:0009405]; proteolysis [GO:0006508]		pathogenesis [GO:0009405]; proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d3u1sl1_d4ogyl2__1		Metazoa		Chordata								
d3u25a__d2ppea2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3u25b__d1j9qa2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3u2ka__d3hyya___1		Metazoa	Firmicutes	Chordata	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3u2la__d2hj3a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; identical protein binding [GO:0042802]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]			cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; identical protein binding [GO:0042802]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]
d3u2ma__d3r7cb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]; cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573]; response to lipopolysaccharide [GO:0032496]		cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573]; response to lipopolysaccharide [GO:0032496]	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]
d3u2ma__d4e0ha1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	cell [GO:0005623]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; protein import into mitochondrial intermembrane space [GO:0045041]		cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; protein import into mitochondrial intermembrane space [GO:0045041]	cytosol [GO:0005829]; extracellular region [GO:0005576]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	cell [GO:0005623]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; growth factor activity [GO:0008083]; protein disulfide oxidoreductase activity [GO:0015035]	flavin adenine dinucleotide binding [GO:0050660]; flavin-linked sulfhydryl oxidase activity [GO:0016971]; protein disulfide oxidoreductase activity [GO:0015035]; thiol oxidase activity [GO:0016972]
d3u2qa2_d3i1fb2__1			Actinobacteria	Crenarchaeota	extracellular region [GO:0005576]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	extracellular region [GO:0005576]	cytosol [GO:0005829]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d3u2qa3_d1jnya2__1			Actinobacteria	Crenarchaeota	extracellular region [GO:0005576]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]		extracellular region [GO:0005576]	cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3u2sl1_d3ciqj___1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3u2sl2_d4odub1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d3u2va1_d1nkhd___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]; glycogenin glucosyltransferase activity [GO:0008466]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity [GO:0102751]; glycogen biosynthetic process [GO:0005978]; neutrophil degranulation [GO:0043312]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	glycogen biosynthetic process [GO:0005978]; neutrophil degranulation [GO:0043312]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	glycogenin glucosyltransferase activity [GO:0008466]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity [GO:0102751]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d3u2vb1_d1h5tb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]; glycogenin glucosyltransferase activity [GO:0008466]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity [GO:0102751]; glycogen biosynthetic process [GO:0005978]; neutrophil degranulation [GO:0043312]	cytosol [GO:0005829]; glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	glycogen biosynthetic process [GO:0005978]; neutrophil degranulation [GO:0043312]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]	cytosol [GO:0005829]	glycogenin glucosyltransferase activity [GO:0008466]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity [GO:0102751]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3u30a2_d4gdka___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	Atg12-Atg5-Atg16 complex [GO:0034274]; autophagosome [GO:0005776]; axoneme [GO:0005930]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; phagocytic vesicle membrane [GO:0030670]; phagophore assembly site membrane [GO:0034045]; aggrephagy [GO:0035973]; antigen processing and presentation of endogenous antigen [GO:0019883]; apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; blood vessel remodeling [GO:0001974]; C-terminal protein lipidation [GO:0006501]; cellular homeostasis [GO:0019725]; cellular response to nitrogen starvation [GO:0006995]; cellular response to nitrosative stress [GO:0071500]; heart contraction [GO:0060047]; macroautophagy [GO:0016236]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative stranded viral RNA replication [GO:0039689]; negative thymic T cell selection [GO:0045060]; otolith development [GO:0048840]; positive regulation by symbiont of host autophagy [GO:0075044]; positive regulation of mucus secretion [GO:0070257]; post-translational protein modification [GO:0043687]; protein lipidation involved in autophagosome assembly [GO:0061739]; regulation of cilium assembly [GO:1902017]; regulation of cytokine secretion involved in immune response [GO:0002739]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to drug [GO:0042493]; response to fungus [GO:0009620]; vasodilation [GO:0042311]; ventricular cardiac muscle cell development [GO:0055015]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	aggrephagy [GO:0035973]; antigen processing and presentation of endogenous antigen [GO:0019883]; apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; blood vessel remodeling [GO:0001974]; cellular homeostasis [GO:0019725]; cellular response to nitrogen starvation [GO:0006995]; cellular response to nitrosative stress [GO:0071500]; C-terminal protein lipidation [GO:0006501]; heart contraction [GO:0060047]; macroautophagy [GO:0016236]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative stranded viral RNA replication [GO:0039689]; negative thymic T cell selection [GO:0045060]; otolith development [GO:0048840]; positive regulation by symbiont of host autophagy [GO:0075044]; positive regulation of mucus secretion [GO:0070257]; post-translational protein modification [GO:0043687]; protein lipidation involved in autophagosome assembly [GO:0061739]; regulation of cilium assembly [GO:1902017]; regulation of cytokine secretion involved in immune response [GO:0002739]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to drug [GO:0042493]; response to fungus [GO:0009620]; vasodilation [GO:0042311]; ventricular cardiac muscle cell development [GO:0055015]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	Atg12-Atg5-Atg16 complex [GO:0034274]; autophagosome [GO:0005776]; axoneme [GO:0005930]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondria-associated endoplasmic reticulum membrane [GO:0044233]; phagocytic vesicle membrane [GO:0030670]; phagophore assembly site membrane [GO:0034045]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	
d3u30b2_d1t66h2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]		protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	
d3u30b2_d3fb5a1__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	voltage-gated potassium channel complex [GO:0008076]; identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	voltage-gated potassium channel complex [GO:0008076]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	identical protein binding [GO:0042802]; voltage-gated potassium channel activity [GO:0005249]
d3u30d1_d3r3md1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]
d3u30e1_d2j6eb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3u30e2_d1ggch1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3u34b__d1wlia___1			Proteobacteria	Proteobacteria	cofactor binding [GO:0048037]	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	cofactor binding [GO:0048037]	cofactor binding [GO:0048037]
d3u34c__d3tgva1__1			Proteobacteria	Proteobacteria	cofactor binding [GO:0048037]	coenzyme F420 binding [GO:0070967]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; heme transport [GO:0015886]		heme transport [GO:0015886]			cofactor binding [GO:0048037]	coenzyme F420 binding [GO:0070967]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d3u34d__d1wlkb___1			Proteobacteria	Proteobacteria	cofactor binding [GO:0048037]	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	cofactor binding [GO:0048037]	cofactor binding [GO:0048037]
d3u35a__d3tgvb1__1			Proteobacteria	Proteobacteria	cofactor binding [GO:0048037]	coenzyme F420 binding [GO:0070967]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; heme transport [GO:0015886]		heme transport [GO:0015886]			cofactor binding [GO:0048037]	coenzyme F420 binding [GO:0070967]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d3u35c__d1i0sa___1			Proteobacteria	Euryarchaeota	cofactor binding [GO:0048037]	FMN binding [GO:0010181]; oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [GO:0016723]; protein homodimerization activity [GO:0042803]					cofactor binding [GO:0048037]	FMN binding [GO:0010181]; oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [GO:0016723]; protein homodimerization activity [GO:0042803]
d3u35c__d2d37a1__1			Proteobacteria	Crenarchaeota	cofactor binding [GO:0048037]	FMN binding [GO:0010181]; phenol 2-monooxygenase activity [GO:0018662]					cofactor binding [GO:0048037]	FMN binding [GO:0010181]; phenol 2-monooxygenase activity [GO:0018662]
d3u3ea__d3bcqc___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3u3gb__d2dffa___1				Euryarchaeota	nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	cytoplasm [GO:0005737]; ribonuclease H2 complex [GO:0032299]; manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; DNA replication, removal of RNA primer [GO:0043137]; mismatch repair [GO:0006298]		DNA replication, removal of RNA primer [GO:0043137]; mismatch repair [GO:0006298]		cytoplasm [GO:0005737]; ribonuclease H2 complex [GO:0032299]	nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	manganese ion binding [GO:0030145]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]
d3u3gd__d4pwda2__1					nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3u3ka__d1rrpc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; aryl sulfotransferase activity [GO:0004062]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytosol [GO:0005829]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	aryl sulfotransferase activity [GO:0004062]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3u40b__d1rxcf___1				Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	nucleoside metabolic process [GO:0009116]	cellular response to DNA damage stimulus [GO:0006974]; nucleotide catabolic process [GO:0009166]; protein hexamerization [GO:0034214]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]		cytosol [GO:0005829]	purine-nucleoside phosphorylase activity [GO:0004731]	identical protein binding [GO:0042802]; potassium ion binding [GO:0030955]; uridine phosphorylase activity [GO:0004850]
d3u43a1_d2k0dx___1			Proteobacteria	Proteobacteria	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]	bacteriocin immunity [GO:0030153]			toxic substance binding [GO:0015643]	toxic substance binding [GO:0015643]
d3u46b2_d4m6ml2__1												
d3u46l1_d4jpil2__1												
d3u4bl2_d1qlrb1__1		Metazoa		Chordata								
d3u4bl2_d3tnnb2__1												
d3u4eb2_d1qbml2__1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	structural molecule activity [GO:0005198]	
d3u4eb2_d3u6rh___1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d3u4el1_d3naal2__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d3u4el1_d4elkb1__1					host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]	
d3u4el2_d5b8ca___1		Metazoa		Chordata	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	structural molecule activity [GO:0005198]	
d3u4xa__d1uypc1__1	Viridiplantae		Streptophyta	Thermotogae	calcium ion binding [GO:0005509]; glucose binding [GO:0005536]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]	beta-fructofuranosidase activity [GO:0004564]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			calcium ion binding [GO:0005509]; glucose binding [GO:0005536]; manganese ion binding [GO:0030145]; mannose binding [GO:0005537]	beta-fructofuranosidase activity [GO:0004564]
d3u53a__d1muta___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity [GO:0008803]; GTP binding [GO:0005525]; apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; nucleobase-containing compound metabolic process [GO:0006139]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; nucleobase-containing compound metabolic process [GO:0006139]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	mitochondrial matrix [GO:0005759]		bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [GO:0004081]; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity [GO:0008803]; GTP binding [GO:0005525]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; 8-oxo-dGDP phosphatase activity [GO:0044715]; 8-oxo-GDP phosphatase activity [GO:0044716]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]
d3u5ja__d2d9ea1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; MOZ/MORF histone acetyltransferase complex [GO:0070776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; histone H3 acetylation [GO:0043966]; histone H3-K23 acetylation [GO:0043972]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	histone H3 acetylation [GO:0043966]; histone H3-K23 acetylation [GO:0043972]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; MOZ/MORF histone acetyltransferase complex [GO:0070776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d3u5la__d5cgpa___1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d3u5re__d4xhma___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]	cell [GO:0005623]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]	protein disulfide oxidoreductase activity [GO:0015035]
d3u5rf__d3i69f1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3u5rg__d1j0fa1__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; nuclear body [GO:0016604]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]
d3u5rh__d1iyib2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	antioxidant activity [GO:0016209]; oxidoreductase activity [GO:0016491]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d3u6ba3_d4j0qc3__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]		extracellular region [GO:0005576]	cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3u6bb3_d4rd6a3__1			Actinobacteria	Crenarchaeota	extracellular region [GO:0005576]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	extracellular region [GO:0005576]	cytosol [GO:0005829]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d3u6ra__d3l1ol2__1												
d3u6va2_d3w8sa2__1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	transferase activity [GO:0016740]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	transferase activity [GO:0016740]
d3u6vb2_d2a2sb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3u6xi2_d1uxbb___1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]	viral capsid [GO:0019028]		metal ion binding [GO:0046872]
d3u6xk2_d1qhva___1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]; adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	adhesion receptor-mediated virion attachment to host cell [GO:0098671]; cell adhesion [GO:0007155]; viral entry into host cell [GO:0046718]	virus tail, baseplate [GO:0098025]	host cell nucleus [GO:0042025]; viral capsid [GO:0019028]		
d3u6xq2_d4k6tc___1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]	viral capsid [GO:0019028]		metal ion binding [GO:0046872]
d3u6xr2_d3cncd___1					virus tail, baseplate [GO:0098025]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	cell adhesion [GO:0007155]; virion attachment to host cell [GO:0019062]	virus tail, baseplate [GO:0098025]	viral capsid [GO:0019028]		
d3u6yc__d4z9ea___1			Crenarchaeota	Euryarchaeota	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]			chromosome [GO:0005694]; cytoplasm [GO:0005737]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]
d3u70a__d1f8qa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]	defense response [GO:0006952]; negative regulation of translation [GO:0017148]			nucleotide binding [GO:0000166]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3u71a__d2nmyb___1					aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3u79a__d2bx5j___1		Metazoa		Chordata								
d3u79a__d5grya2__1												
d3u79c__d4ki5d1__1		Metazoa		Chordata		COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]		acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]		COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]		copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]
d3u79d__d43cag___1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3u79f__d4f7ea2__1		Metazoa		Chordata		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; immune response [GO:0006955]		extracellular region [GO:0005576]; MHC class I protein complex [GO:0042612]		
d3u79g__d4at6k2__1												
d3u7aa__d1svza1__1		Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; antigen binding [GO:0003823]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		antigen binding [GO:0003823]
d3u7ba__d2j8ga2__1	Fungi		Ascomycota		extracellular space [GO:0005615]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	xylan catabolic process [GO:0045493]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular space [GO:0005615]		endo-1,4-beta-xylanase activity [GO:0031176]	lysozyme activity [GO:0003796]
d3u7bc__d1iswa2__1	Fungi		Ascomycota	Actinobacteria	extracellular space [GO:0005615]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]	extracellular space [GO:0005615]		endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d3u7bd__d3olga1__1	Fungi	Metazoa	Ascomycota	Chordata	extracellular space [GO:0005615]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	xylan catabolic process [GO:0045493]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	extracellular space [GO:0005615]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	endo-1,4-beta-xylanase activity [GO:0031176]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3u7be__d5i3db___1	Fungi		Ascomycota	Crenarchaeota	extracellular space [GO:0005615]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]		endo-1,4-beta-xylanase activity [GO:0031176]	beta-galactosidase activity [GO:0004565]; beta-glucosidase activity [GO:0008422]
d3u7qa__d5vq4d___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d3u7qc__d1m1nd___1			Proteobacteria	Proteobacteria	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	nitrogen fixation [GO:0009399]	molybdenum-iron nitrogenase complex [GO:0016612]	molybdenum-iron nitrogenase complex [GO:0016612]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d3u7ua3_d2uzxa1__1	Metazoa	Metazoa	Chordata	Chordata	basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; extracellular region [GO:0005576]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; epidermal growth factor receptor binding [GO:0005154]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transcription regulatory region DNA binding [GO:0044212]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; cardiac muscle tissue regeneration [GO:0061026]; cell fate commitment [GO:0045165]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; central nervous system morphogenesis [GO:0021551]; embryonic pattern specification [GO:0009880]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; mammary gland epithelial cell differentiation [GO:0060644]; MAPK cascade [GO:0000165]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron migration [GO:2001223]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; olfactory bulb interneuron differentiation [GO:0021889]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; hepatocyte growth factor-activated receptor activity [GO:0005008]; identical protein binding [GO:0042802]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; semaphorin receptor activity [GO:0017154]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; branching morphogenesis of an epithelial tube [GO:0048754]; cell surface receptor signaling pathway [GO:0007166]; endothelial cell morphogenesis [GO:0001886]; entry of bacterium into host cell [GO:0035635]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of autophagy [GO:0010507]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cardiac muscle tissue regeneration [GO:0061026]; cell fate commitment [GO:0045165]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; central nervous system morphogenesis [GO:0021551]; embryonic pattern specification [GO:0009880]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; mammary gland epithelial cell differentiation [GO:0060644]; MAPK cascade [GO:0000165]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron migration [GO:2001223]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; olfactory bulb interneuron differentiation [GO:0021889]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; regulation of cell migration [GO:0030334]; regulation of cell motility [GO:2000145]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	branching morphogenesis of an epithelial tube [GO:0048754]; cell surface receptor signaling pathway [GO:0007166]; endothelial cell morphogenesis [GO:0001886]; entry of bacterium into host cell [GO:0035635]; establishment of skin barrier [GO:0061436]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; negative regulation of autophagy [GO:0010507]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription by RNA polymerase II [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; extracellular region [GO:0005576]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; receptor complex [GO:0043235]	basal plasma membrane [GO:0009925]; cell surface [GO:0009986]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	ATP binding [GO:0005524]; epidermal growth factor receptor binding [GO:0005154]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase activity [GO:0004713]; transcription regulatory region DNA binding [GO:0044212]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]	ATP binding [GO:0005524]; hepatocyte growth factor-activated receptor activity [GO:0005008]; identical protein binding [GO:0042802]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; semaphorin receptor activity [GO:0017154]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d3u7yl1_d4z7uh1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	nutrient reservoir activity [GO:0045735]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	nutrient reservoir activity [GO:0045735]
d3u86a1_d5ddea1__1	Metazoa	Metazoa	Chordata	Chordata	chromatin [GO:0000785]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; protein-DNA complex [GO:0032993]; transcription factor AP-1 complex [GO:0035976]; transcription factor complex [GO:0005667]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; nuclear receptor binding [GO:0016922]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; aging [GO:0007568]; cellular response to calcium ion [GO:0071277]; cellular response to hormone stimulus [GO:0032870]; circadian rhythm [GO:0007623]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast development [GO:0002076]; positive regulation of cell differentiation [GO:0045597]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]; response to cAMP [GO:0051591]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to light stimulus [GO:0009416]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to organic substance [GO:0010033]; response to peptide hormone [GO:0043434]; response to radiation [GO:0009314]; transcription by RNA polymerase II [GO:0006366]	cell [GO:0005623]; chromatin [GO:0000785]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; histone methyltransferase complex [GO:0035097]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; four-way junction DNA binding [GO:0000400]; protein binding, bridging [GO:0030674]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; transcription regulatory region DNA binding [GO:0044212]; Y-form DNA binding [GO:0000403]; beta-catenin-TCF complex assembly [GO:1904837]; brain development [GO:0007420]; cellular protein metabolic process [GO:0044267]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to glucose stimulus [GO:0071333]; cellular response to peptide hormone stimulus [GO:0071375]; decidualization [GO:0046697]; DNA repair [GO:0006281]; histone lysine methylation [GO:0034968]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of JNK cascade [GO:0046329]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; osteoblast development [GO:0002076]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; post-translational protein modification [GO:0043687]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of type B pancreatic cell proliferation [GO:0061469]; response to gamma radiation [GO:0010332]; response to transforming growth factor beta [GO:0071559]; response to UV [GO:0009411]; type B pancreatic cell differentiation [GO:0003309]	aging [GO:0007568]; cellular response to calcium ion [GO:0071277]; cellular response to hormone stimulus [GO:0032870]; circadian rhythm [GO:0007623]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast development [GO:0002076]; positive regulation of cell differentiation [GO:0045597]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of transcription by RNA polymerase II [GO:0006357]; response to cAMP [GO:0051591]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to light stimulus [GO:0009416]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to organic substance [GO:0010033]; response to peptide hormone [GO:0043434]; response to radiation [GO:0009314]; transcription by RNA polymerase II [GO:0006366]	beta-catenin-TCF complex assembly [GO:1904837]; brain development [GO:0007420]; cellular protein metabolic process [GO:0044267]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to glucose stimulus [GO:0071333]; cellular response to peptide hormone stimulus [GO:0071375]; decidualization [GO:0046697]; DNA repair [GO:0006281]; histone lysine methylation [GO:0034968]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of JNK cascade [GO:0046329]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast development [GO:0002076]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; post-translational protein modification [GO:0043687]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of type B pancreatic cell proliferation [GO:0061469]; response to gamma radiation [GO:0010332]; response to transforming growth factor beta [GO:0071559]; response to UV [GO:0009411]; type B pancreatic cell differentiation [GO:0003309]	chromatin [GO:0000785]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; protein-DNA complex [GO:0032993]; transcription factor AP-1 complex [GO:0035976]; transcription factor complex [GO:0005667]	cell [GO:0005623]; chromatin [GO:0000785]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; histone methyltransferase complex [GO:0035097]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; nuclear receptor binding [GO:0016922]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; four-way junction DNA binding [GO:0000400]; protein binding, bridging [GO:0030674]; protein N-terminus binding [GO:0047485]; R-SMAD binding [GO:0070412]; transcription regulatory region DNA binding [GO:0044212]; Y-form DNA binding [GO:0000403]
d3u8ha__d5g3mb___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]; antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipase activity [GO:0004620]; arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; axon guidance [GO:0007411]; cellular response to leukemia inhibitory factor [GO:1990830]; cholesterol homeostasis [GO:0042632]; lipid catabolic process [GO:0016042]; lysophospholipid transport [GO:0051977]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of prostaglandin secretion [GO:0032308]; regulation of macrophage activation [GO:0043030]	antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; axon guidance [GO:0007411]; cellular response to leukemia inhibitory factor [GO:1990830]; cholesterol homeostasis [GO:0042632]; lipid catabolic process [GO:0016042]; lysophospholipid transport [GO:0051977]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of prostaglandin secretion [GO:0032308]; regulation of macrophage activation [GO:0043030]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipase activity [GO:0004620]
d3u8hb__d5tfva___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]; calcium ion binding [GO:0005509]; calcium-dependent phospholipase A2 activity [GO:0047498]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]; antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	antimicrobial humoral response [GO:0019730]; arachidonic acid secretion [GO:0050482]; defense response to Gram-positive bacterium [GO:0050830]; lipid catabolic process [GO:0016042]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of T cell proliferation [GO:0042130]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; phosphatidylglycerol acyl-chain remodeling [GO:0036148]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylserine acyl-chain remodeling [GO:0036150]; phospholipid metabolic process [GO:0006644]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response [GO:0050729]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; secretory granule [GO:0030141]	extracellular region [GO:0005576]	calcium-dependent phospholipase A2 activity [GO:0047498]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; phospholipid binding [GO:0005543]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; toxin activity [GO:0090729]
d3u8ja__d4afob___1	Metazoa		Mollusca		cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]				cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]		extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	
d3u8jd__d5afke___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3u8uc__d3u8ua___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]
d3u8uf__d2uyrx___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	extracellular region [GO:0005576]; sphingomyelin phosphodiesterase activity [GO:0004767]; hemolysis in other organism [GO:0044179]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	hemolysis in other organism [GO:0044179]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	extracellular region [GO:0005576]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]	sphingomyelin phosphodiesterase activity [GO:0004767]
d3u8xa2_d5azjb1__1	Metazoa		Chordata		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d3u8zb2_d1xd4b3__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleosome [GO:0000786]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; DNA binding [GO:0003677]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein heterodimerization activity [GO:0046982]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; SH3 domain binding [GO:0017124]; axon guidance [GO:0007411]; B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; vitellogenesis [GO:0007296]	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	axon guidance [GO:0007411]; B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; vitellogenesis [GO:0007296]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuronal cell body [GO:0043025]; nucleosome [GO:0000786]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]	actin binding [GO:0003779]	DNA binding [GO:0003677]; GTPase activator activity [GO:0005096]; guanyl-nucleotide exchange factor activity [GO:0005085]; protein heterodimerization activity [GO:0046982]; Ras guanyl-nucleotide exchange factor activity [GO:0005088]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; SH3 domain binding [GO:0017124]
d3u8zc3_d3m1ib___1	Metazoa	Fungi	Chordata	Ascomycota	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cytoplasm [GO:0005737]; nuclear pore [GO:0005643]; nucleus [GO:0005634]; GTPase activator activity [GO:0005096]; Ran GTPase binding [GO:0008536]; G1/S transition of mitotic cell cycle [GO:0000082]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; ubiquitin-dependent protein catabolic process [GO:0006511]	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	G1/S transition of mitotic cell cycle [GO:0000082]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; ubiquitin-dependent protein catabolic process [GO:0006511]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]; nuclear pore [GO:0005643]; nucleus [GO:0005634]	actin binding [GO:0003779]	GTPase activator activity [GO:0005096]; Ran GTPase binding [GO:0008536]
d3u8zd2_d1v5pa1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; positive regulation of cell-matrix adhesion [GO:0001954]	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	positive regulation of cell-matrix adhesion [GO:0001954]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]	fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; PDZ domain binding [GO:0030165]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]
d3u92b__d3g62a1__1	Metazoa		Chordata		axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]		axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]		glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d3u94a__d3axfa___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]	outer membrane-bounded periplasmic space [GO:0030288]; ATPase-coupled molybdate transmembrane transporter activity [GO:0015412]; molybdate ion binding [GO:0030973]; molybdenum ion binding [GO:0030151]; tungstate binding [GO:1901359]; molybdate ion transport [GO:0015689]; response to chromate [GO:0046687]	chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]	molybdate ion transport [GO:0015689]; response to chromate [GO:0046687]	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]	outer membrane-bounded periplasmic space [GO:0030288]	glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	ATPase-coupled molybdate transmembrane transporter activity [GO:0015412]; molybdate ion binding [GO:0030973]; molybdenum ion binding [GO:0030151]; tungstate binding [GO:1901359]
d3u94b__d3tcff___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]; chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]	chaperone-mediated protein folding [GO:0061077]; oligopeptide transport [GO:0006857]; protein transport [GO:0015031]; response to heat [GO:0009408]	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	oligopeptide binding [GO:1900750]; peptide transmembrane transporter activity [GO:1904680]
d3u94d1_d2ylna___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; regulation of membrane potential [GO:0042391]; synaptic transmission, glutamatergic [GO:0035249]		axon [GO:0030424]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; terminal bouton [GO:0043195]		glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]	
d3u95a2_d5nqbb2__1		Metazoa	Thermotogae	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		cytoplasm [GO:0005737]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	L-lactate dehydrogenase activity [GO:0004459]
d3u95b1_d1qydb___1		Viridiplantae	Thermotogae	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]	lariciresinol reductase activity [GO:0010284]; pinoresinol reductase activity [GO:0010283]; (+)-lariciresinol biosynthetic process [GO:1902132]; (+)-pinoresinol catabolic process [GO:1902125]; (+)-secoisolariciresinol biosynthetic process [GO:1902135]; (-)-lariciresinol biosynthetic process [GO:1902129]; (-)-lariciresinol catabolic process [GO:1902128]; (-)-pinoresinol catabolic process [GO:1902123]; lignan biosynthetic process [GO:0009807]	carbohydrate metabolic process [GO:0005975]	(-)-lariciresinol biosynthetic process [GO:1902129]; (-)-lariciresinol catabolic process [GO:1902128]; (-)-pinoresinol catabolic process [GO:1902123]; (+)-lariciresinol biosynthetic process [GO:1902132]; (+)-pinoresinol catabolic process [GO:1902125]; (+)-secoisolariciresinol biosynthetic process [GO:1902135]; lignan biosynthetic process [GO:0009807]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	lariciresinol reductase activity [GO:0010284]; pinoresinol reductase activity [GO:0010283]
d3u95c1_d3pqda1__1			Thermotogae	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	L-lactate dehydrogenase activity [GO:0004459]
d3u96a__d2vexa___1		Metazoa	Proteobacteria	Chordata	extracellular region [GO:0005576]; protein tyrosine phosphatase activity [GO:0004725]; pathogenesis [GO:0009405]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	pathogenesis [GO:0009405]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	extracellular region [GO:0005576]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3u9dc2_d1gljy2__1	Metazoa		Arthropoda	Proteobacteria	cytosol [GO:0005829]; actin monomer binding [GO:0003785]; actin filament organization [GO:0007015]; brain development [GO:0007420]; larval central nervous system remodeling [GO:0035193]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	actin filament organization [GO:0007015]; brain development [GO:0007420]; larval central nervous system remodeling [GO:0035193]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	cytosol [GO:0005829]	cytosol [GO:0005829]	actin monomer binding [GO:0003785]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d3u9fa__d1dpba___1			Proteobacteria	Proteobacteria	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	pyruvate dehydrogenase complex [GO:0045254]; dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]; glycolytic process [GO:0006096]	response to antibiotic [GO:0046677]	glycolytic process [GO:0006096]		pyruvate dehydrogenase complex [GO:0045254]	chloramphenicol O-acetyltransferase activity [GO:0008811]	dihydrolipoyllysine-residue acetyltransferase activity [GO:0004742]
d3u9fa__d1nm8a1__1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; protein targeting to peroxisome [GO:0006625]	response to antibiotic [GO:0046677]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; protein targeting to peroxisome [GO:0006625]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	chloramphenicol O-acetyltransferase activity [GO:0008811]	carnitine O-acetyltransferase activity [GO:0004092]
d3u9fb__d2ihwg___1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]	response to antibiotic [GO:0046677]			cytoplasm [GO:0005737]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]	chloramphenicol O-acetyltransferase activity [GO:0008811]	acetyltransferase activity [GO:0016407]; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity [GO:0043754]; lipoic acid binding [GO:0031405]; ubiquitin protein ligase binding [GO:0031625]
d3u9fc__d2fy4a2__1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleus [GO:0005634]; presynapse [GO:0098793]; choline O-acetyltransferase activity [GO:0004102]; acetylcholine biosynthetic process [GO:0008292]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; phosphatidylcholine biosynthetic process [GO:0006656]	response to antibiotic [GO:0046677]	acetylcholine biosynthetic process [GO:0008292]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; phosphatidylcholine biosynthetic process [GO:0006656]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; neuron projection [GO:0043005]; nucleus [GO:0005634]; presynapse [GO:0098793]	chloramphenicol O-acetyltransferase activity [GO:0008811]	choline O-acetyltransferase activity [GO:0004102]
d3u9ff__d1scza___1			Proteobacteria	Proteobacteria	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; oxoglutarate dehydrogenase complex [GO:0045252]; dihydrolipoyllysine-residue succinyltransferase activity [GO:0004149]; lipoic acid binding [GO:0031405]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; tricarboxylic acid cycle [GO:0006099]	response to antibiotic [GO:0046677]	L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; oxoglutarate dehydrogenase complex [GO:0045252]	chloramphenicol O-acetyltransferase activity [GO:0008811]	dihydrolipoyllysine-residue succinyltransferase activity [GO:0004149]; lipoic acid binding [GO:0031405]
d3u9fg__d1q6xa1__1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]; choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]; acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	response to antibiotic [GO:0046677]	acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]		cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]	chloramphenicol O-acetyltransferase activity [GO:0008811]	choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]
d3u9fk__d2h3ua1__1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	response to antibiotic [GO:0046677]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]		endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	chloramphenicol O-acetyltransferase activity [GO:0008811]	carnitine O-acetyltransferase activity [GO:0004092]
d3u9fm__d2h3wb1__1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]; carnitine O-acetyltransferase activity [GO:0004092]; carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]	response to antibiotic [GO:0046677]	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid metabolic process [GO:0006631]		endoplasmic reticulum [GO:0005783]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; peroxisome [GO:0005777]	chloramphenicol O-acetyltransferase activity [GO:0008811]	carnitine O-acetyltransferase activity [GO:0004092]
d3u9fn__d3maeb___1			Proteobacteria		chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]				chloramphenicol O-acetyltransferase activity [GO:0008811]	
d3u9fs__d1q6xa2__1		Metazoa	Proteobacteria	Chordata	chloramphenicol O-acetyltransferase activity [GO:0008811]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]; choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]; acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	response to antibiotic [GO:0046677]	acetylcholine biosynthetic process [GO:0008292]; antral ovarian follicle growth [GO:0001547]; memory [GO:0007613]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter biosynthetic process [GO:0042136]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]		cytoplasm [GO:0005737]; neuron projection [GO:0043005]; synapse [GO:0045202]	chloramphenicol O-acetyltransferase activity [GO:0008811]	choline binding [GO:0033265]; choline O-acetyltransferase activity [GO:0004102]
d3u9pl2_d3f58h2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to bacterium [GO:0009617]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to bacterium [GO:0009617]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell [GO:0005623]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3u9pl2_d4x6bd2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to bacterium [GO:0009617]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient levels [GO:0031669]; cellular response to tumor necrosis factor [GO:0071356]; defense response to bacterium [GO:0042742]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; positive regulation of cell projection organization [GO:0031346]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to bacterium [GO:0009617]; response to drug [GO:0042493]; response to herbicide [GO:0009635]; response to mycotoxin [GO:0010046]; response to virus [GO:0009615]; sequestering of iron ion [GO:0097577]; siderophore transport [GO:0015891]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell [GO:0005623]; cytoplasmic vesicle lumen [GO:0060205]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	enterobactin binding [GO:1903981]; iron ion binding [GO:0005506]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; small molecule binding [GO:0036094]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3u9za2_d5gn5b1__1	Metazoa		Chordata		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]		actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d3uaaa1_d4e9sa2__1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d3uaba2_d3t6za2__1		Fungi	Proteobacteria	Basidiomycota	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3uaba2_d4yvua2__1			Proteobacteria	Firmicutes	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	sporulation resulting in formation of a cellular spore [GO:0030435]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	outer membrane-bounded periplasmic space [GO:0030288]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3uada1_d4azuc___1			Proteobacteria	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d3uaga1_d5vvwg1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [GO:0008764]	ATP binding [GO:0005524]; UDP-N-acetylmuramate-L-alanine ligase activity [GO:0008763]
d3uama__d2wljb2__1			Proteobacteria	Proteobacteria		integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; regulation of ion transmembrane transport [GO:0034765]		regulation of ion transmembrane transport [GO:0034765]		integral component of membrane [GO:0016021]		identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]
d3uamb__d1cf1c1__1		Metazoa	Proteobacteria	Chordata		cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]; G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]		G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]		cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]		G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]
d3uamb__d5e6zd1__1			Proteobacteria	Proteobacteria		cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]		carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]		cytosol [GO:0005829]		1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3uamc__d3o7zc1__1			Proteobacteria									
d3uame__d1wcqc1__1			Proteobacteria	Actinobacteria		extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]		metabolic process [GO:0008152]		extracellular region [GO:0005576]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d3uame__d1xl6a1__1			Proteobacteria	Proteobacteria		integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; regulation of ion transmembrane transport [GO:0034765]		regulation of ion transmembrane transport [GO:0034765]		integral component of membrane [GO:0016021]		identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]
d3ub0c1_d2ahma1__1					host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3ubca__d1yffd___1		Metazoa	Verrucomicrobia	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3ubca__d3wctc___1		Metazoa	Verrucomicrobia	Annelida	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3ubee__d4n5yk1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]; identical protein binding [GO:0042802]
d3ubja__d3htoa___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3ubjg__d2wrfc1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3ubqg__d4mhig1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3ubta__d2qyob2__1		Viridiplantae	Proteobacteria	Streptophyta	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	isoflavone 7-O-methyltransferase activity [GO:0033800]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]; aromatic compound biosynthetic process [GO:0019438]	DNA restriction-modification system [GO:0009307]	aromatic compound biosynthetic process [GO:0019438]			DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	isoflavone 7-O-methyltransferase activity [GO:0033800]; O-methyltransferase activity [GO:0008171]; protein dimerization activity [GO:0046983]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757]
d3ubty__d4cwac___1			Proteobacteria	Apicomplexa	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	DNA restriction-modification system [GO:0009307]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]		cytosol [GO:0005829]	DNA (cytosine-5-)-methyltransferase activity [GO:0003886]	spermidine synthase activity [GO:0004766]
d3ubxa1_d1fneb2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3ubxb__d1a7nh___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ubxd1_d1h15d2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]; cognition [GO:0050890]; immune response [GO:0006955]; interferon-gamma-mediated signaling pathway [GO:0060333]; peptide antigen assembly with MHC class II protein complex [GO:0002503]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; integral component of plasma membrane [GO:0005887]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	MHC class II protein complex binding [GO:0023026]; MHC class II receptor activity [GO:0032395]; peptide antigen binding [GO:0042605]; polysaccharide binding [GO:0030247]
d3ubxi1_d1bj1j1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]; activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; induction of positive chemotaxis [GO:0050930]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	activation of protein kinase activity [GO:0032147]; angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; basophil chemotaxis [GO:0002575]; branching involved in blood vessel morphogenesis [GO:0001569]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle fiber development [GO:0048739]; cardiac vascular smooth muscle cell development [GO:0060948]; cell maturation [GO:0048469]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hypoxia [GO:0071456]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular stress response to acid chemical [GO:0097533]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; cytokine-mediated signaling pathway [GO:0019221]; dopaminergic neuron differentiation [GO:0071542]; endothelial cell chemotaxis [GO:0035767]; epithelial cell differentiation [GO:0030855]; eye photoreceptor cell development [GO:0042462]; heart morphogenesis [GO:0003007]; induction of positive chemotaxis [GO:0050930]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lactation [GO:0007595]; lung development [GO:0030324]; lymph vessel morphogenesis [GO:0036303]; macrophage differentiation [GO:0030225]; mammary gland alveolus development [GO:0060749]; mesoderm development [GO:0007498]; monocyte differentiation [GO:0030224]; motor neuron migration [GO:0097475]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of establishment of endothelial barrier [GO:1903141]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; outflow tract morphogenesis [GO:0003151]; ovarian follicle development [GO:0001541]; platelet degranulation [GO:0002576]; positive chemotaxis [GO:0050918]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [GO:0038091]; positive regulation of cellular component movement [GO:0051272]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of mast cell chemotaxis [GO:0060754]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein kinase D signaling [GO:1903572]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vascular permeability [GO:0043117]; post-embryonic camera-type eye development [GO:0031077]; primitive erythrocyte differentiation [GO:0060319]; regulation of cell shape [GO:0008360]; regulation of nitric oxide mediated signal transduction [GO:0010749]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; surfactant homeostasis [GO:0043129]; tube formation [GO:0035148]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculogenesis [GO:0001570]; VEGF-activated neuropilin signaling pathway [GO:0038190]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell-cell adherens junction [GO:0005913]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; platelet alpha granule lumen [GO:0031093]; secretory granule [GO:0030141]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; extracellular matrix binding [GO:0050840]; fibronectin binding [GO:0001968]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; neuropilin binding [GO:0038191]; platelet-derived growth factor receptor binding [GO:0005161]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; receptor ligand activity [GO:0048018]; vascular endothelial growth factor receptor 1 binding [GO:0043183]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; vascular endothelial growth factor receptor binding [GO:0005172]
d3ubxi2_d3m1bc2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ubxl2_d2xacx___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]
d3uc0l1_d4q7da2__1		Metazoa		Chordata	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3uc0l2_d2a9ml___1					host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	
d3uc0m1_d1r0ah2__1					host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell endoplasmic reticulum [GO:0044165]; host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3uc5a__d4mafb2__1		Viridiplantae	Actinobacteria	Streptophyta	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	nucleotide binding [GO:0000166]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; sulfate assimilation [GO:0000103]	coenzyme A biosynthetic process [GO:0015937]; protein hexamerization [GO:0034214]	sulfate assimilation [GO:0000103]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	nucleotide binding [GO:0000166]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d3ucca2_d4m0xb2__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d3uccb1_d2psnb1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of muscle contraction [GO:0045933]; positive regulation of plasminogen activation [GO:0010756]; response to virus [GO:0009615]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	cell cortex region [GO:0099738]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; M band [GO:0031430]; membrane [GO:0016020]; nucleus [GO:0005634]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	cadherin binding [GO:0045296]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; GTPase binding [GO:0051020]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d3ucda2_d3zlgc2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3ucea__d4kuhc1__1			Proteobacteria	Firmicutes	identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]		fatty acid metabolic process [GO:0006631]			identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-hydroxybutyryl-CoA dehydrogenase activity [GO:0008691]; NAD+ binding [GO:0070403]
d3uceb__d1sbyb___1		Metazoa	Proteobacteria	Arthropoda	identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]; alcohol metabolic process [GO:0006066]		alcohol metabolic process [GO:0006066]			identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; identical protein binding [GO:0042802]
d3uceb__d2pwze1__1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]
d3uced__d1wpqb1__1		Metazoa	Proteobacteria	Chordata	identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycerol-3-phosphate dehydrogenase (quinone) activity [GO:0004368]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]; cellular response to cAMP [GO:0071320]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophosphate shuttle [GO:0006127]; NADH oxidation [GO:0006116]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of glycolytic process [GO:0045821]		cellular response to cAMP [GO:0071320]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerophosphate shuttle [GO:0006127]; NADH oxidation [GO:0006116]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of glycolytic process [GO:0045821]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glycerol-3-phosphate dehydrogenase complex [GO:0009331]	identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	glycerol-3-phosphate dehydrogenase (quinone) activity [GO:0004368]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; NAD binding [GO:0051287]; protein homodimerization activity [GO:0042803]
d3ucsc1_d2ctpa1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; nucleoid [GO:0009295]; bent DNA binding [GO:0003681]; unfolded protein binding [GO:0051082]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein refolding [GO:0042026]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of endoplasmic reticulum membrane [GO:0030176]; membrane [GO:0016020]; nuclear membrane [GO:0031965]; Hsp70 protein binding [GO:0030544]; cellular protein-containing complex assembly [GO:0034622]; cellular response to misfolded protein [GO:0071218]; chaperone cofactor-dependent protein refolding [GO:0051085]; ERAD pathway [GO:0036503]; ubiquitin-dependent ERAD pathway [GO:0030433]	chaperone cofactor-dependent protein refolding [GO:0051085]; protein refolding [GO:0042026]	cellular protein-containing complex assembly [GO:0034622]; cellular response to misfolded protein [GO:0071218]; chaperone cofactor-dependent protein refolding [GO:0051085]; ERAD pathway [GO:0036503]; ubiquitin-dependent ERAD pathway [GO:0030433]	cytoplasm [GO:0005737]; nucleoid [GO:0009295]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of endoplasmic reticulum membrane [GO:0030176]; membrane [GO:0016020]; nuclear membrane [GO:0031965]	bent DNA binding [GO:0003681]; unfolded protein binding [GO:0051082]	Hsp70 protein binding [GO:0030544]
d3uctb__d2otgb___1	Metazoa	Metazoa	Chordata	Mollusca	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	myosin complex [GO:0016459]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]		calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	myosin complex [GO:0016459]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	actin filament binding [GO:0051015]; ATP binding [GO:0005524]; motor activity [GO:0003774]
d3ucwd__d1ej3a___1	Metazoa	Metazoa	Chordata	Cnidaria	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	calcium ion binding [GO:0005509]; bioluminescence [GO:0008218]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	bioluminescence [GO:0008218]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]		adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]
d3uczp__d5iqqc___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 14-3-3 protein binding [GO:0071889]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]; meiotic cell cycle [GO:0051321]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; snRNA catabolic process [GO:0016076]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	meiotic cell cycle [GO:0051321]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; snRNA catabolic process [GO:0016076]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	14-3-3 protein binding [GO:0071889]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]
d3ud4p__d1uw4c___1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; exon-exon junction complex [GO:0035145]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]; animal organ regeneration [GO:0031100]; liver development [GO:0001889]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]	animal organ regeneration [GO:0031100]; liver development [GO:0001889]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]	cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; exon-exon junction complex [GO:0035145]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]	RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]
d3ud7a__d3wo3c___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]
d3udab__d1cvsb___1	Metazoa	Metazoa	Chordata	Chordata	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]; activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of MAPK activity [GO:0000187]; animal organ morphogenesis [GO:0009887]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemotaxis [GO:0006935]; chondroblast differentiation [GO:0060591]; cytokine-mediated signaling pathway [GO:0019221]; embryonic morphogenesis [GO:0048598]; extracellular matrix organization [GO:0030198]; fibroblast growth factor receptor signaling pathway [GO:0008543]; growth factor dependent regulation of skeletal muscle satellite cell proliferation [GO:0014843]; hyaluronan catabolic process [GO:0030214]; inositol phosphate biosynthetic process [GO:0032958]; MAPK cascade [GO:0000165]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of cell death [GO:0060548]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of wound healing [GO:0061045]; nervous system development [GO:0007399]; paracrine signaling [GO:0038001]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of cell fate specification [GO:0042660]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; release of sequestered calcium ion into cytosol [GO:0051209]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; stem cell proliferation [GO:0072089]; wound healing [GO:0042060]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cell [GO:0005623]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; integrin binding [GO:0005178]; nuclear receptor transcription coactivator activity [GO:0030374]; receptor-receptor interaction [GO:0090722]
d3udud__d5kvub___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; isocitrate dehydrogenase activity [GO:0004448]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; isocitrate dehydrogenase activity [GO:0004448]; magnesium ion binding [GO:0000287]; protein homodimerization activity [GO:0042803]
d3udue__d1zorb___1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]		3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]
d3udue__d3vmka1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	leucine biosynthetic process [GO:0009098]	leucine biosynthetic process [GO:0009098]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d3uduf__d1qzta___1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	plasma membrane [GO:0005886]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	leucine biosynthetic process [GO:0009098]	acetyl-CoA biosynthetic process [GO:0006085]	cytoplasm [GO:0005737]	plasma membrane [GO:0005886]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	phosphate acetyltransferase activity [GO:0008959]
d3udwc__d5d5mf2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; signaling receptor binding [GO:0005102]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of T cell activation [GO:0050868]; positive regulation of interleukin-10 production [GO:0032733]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	negative regulation of interleukin-12 production [GO:0032695]; negative regulation of T cell activation [GO:0050868]; positive regulation of interleukin-10 production [GO:0032733]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; signaling receptor binding [GO:0005102]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ue4a__d1j7lb___1	Metazoa		Chordata	Firmicutes	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]; actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; B-1 B cell homeostasis [GO:0001922]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	ATP binding [GO:0005524]; kanamycin kinase activity [GO:0008910]; response to antibiotic [GO:0046677]	actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiovascular system development [GO:0072358]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation blood vessel branching [GO:1905555]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333]	response to antibiotic [GO:0046677]	actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991]		actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]	ATP binding [GO:0005524]; kanamycin kinase activity [GO:0008910]
d3ue6d__d3nhqh1__1				Proteobacteria	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3ue6e__d1gsxa___1				Proteobacteria	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d3uela__d1gytc1__1	Metazoa		Chordata	Proteobacteria	chromatin [GO:0000785]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; poly(ADP-ribose) glycohydrolase activity [GO:0004649]; ATP generation from poly-ADP-D-ribose [GO:1990966]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-sugar metabolic process [GO:0009225]; positive regulation of DNA repair [GO:0045739]; regulation of DNA repair [GO:0006282]	cytoplasm [GO:0005737]; aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]; peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	ATP generation from poly-ADP-D-ribose [GO:1990966]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-sugar metabolic process [GO:0009225]; positive regulation of DNA repair [GO:0045739]; regulation of DNA repair [GO:0006282]	peptide catabolic process [GO:0043171]; plasmid maintenance [GO:0006276]; plasmid recombination [GO:0042150]; transcription, DNA-templated [GO:0006351]	chromatin [GO:0000785]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	chromatin binding [GO:0003682]; poly(ADP-ribose) glycohydrolase activity [GO:0004649]	aminopeptidase activity [GO:0004177]; DNA binding [GO:0003677]; manganese ion binding [GO:0030145]; metalloexopeptidase activity [GO:0008235]; transcription antitermination factor activity, DNA binding [GO:0001073]
d3uelc__d5cb5p___1	Metazoa		Chordata	Proteobacteria	chromatin [GO:0000785]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; poly(ADP-ribose) glycohydrolase activity [GO:0004649]; ATP generation from poly-ADP-D-ribose [GO:1990966]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-sugar metabolic process [GO:0009225]; positive regulation of DNA repair [GO:0045739]; regulation of DNA repair [GO:0006282]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]; negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	ATP generation from poly-ADP-D-ribose [GO:1990966]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; nucleotide-sugar metabolic process [GO:0009225]; positive regulation of DNA repair [GO:0045739]; regulation of DNA repair [GO:0006282]	negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	chromatin [GO:0000785]; cytoplasm [GO:0005737]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]		chromatin binding [GO:0003682]; poly(ADP-ribose) glycohydrolase activity [GO:0004649]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]
d3uf0a__d1d4fc1__1		Metazoa	Actinobacteria	Chordata	2-deoxy-D-gluconate 3-dehydrogenase activity [GO:0008678]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]; adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]; chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		chronic inflammatory response to antigenic stimulus [GO:0002439]; circadian sleep/wake cycle [GO:0042745]; one-carbon metabolic process [GO:0006730]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353]		cytosol [GO:0005829]; melanosome [GO:0042470]; neuron projection [GO:0043005]; nucleus [GO:0005634]	2-deoxy-D-gluconate 3-dehydrogenase activity [GO:0008678]; nucleotide binding [GO:0000166]	adenosylhomocysteinase activity [GO:0004013]; adenosylselenohomocysteinase activity [GO:0098604]; adenyl nucleotide binding [GO:0030554]; identical protein binding [GO:0042802]; NAD binding [GO:0051287]
d3uf3a__d4rvjb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3uf3b__d3s85b___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ufna__d4hegb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ugea__d4dpbx___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3ugec__d4e9pa2__1			Proteobacteria		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	
d3uged__d1aq8a2__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	oxidation-reduction process [GO:0055114]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3ugja3_d2hrya2__1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleotide biosynthetic process [GO:0006164]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]
d3ugja6_d5dd7a2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; thiamine-phosphate kinase activity [GO:0009030]
d3ugja7_d1ipha1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3ugja7_d1l9xb1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]; 'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; vacuole [GO:0005773]; exopeptidase activity [GO:0008238]; gamma-glutamyl-peptidase activity [GO:0034722]; omega peptidase activity [GO:0008242]; neutrophil degranulation [GO:0043312]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]	neutrophil degranulation [GO:0043312]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]	cytoplasm [GO:0005737]	azurophil granule lumen [GO:0035578]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; melanosome [GO:0042470]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; vacuole [GO:0005773]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; phosphoribosylformylglycinamidine synthase activity [GO:0004642]	exopeptidase activity [GO:0008238]; gamma-glutamyl-peptidase activity [GO:0034722]; omega peptidase activity [GO:0008242]
d3ugua2_d6cgta1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]; G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	G protein-coupled receptor internalization [GO:0002031]; response to light stimulus [GO:0009416]; signal transduction [GO:0007165]	carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]	extracellular region [GO:0005576]	G protein-coupled receptor binding [GO:0001664]; identical protein binding [GO:0042802]; opsin binding [GO:0002046]; phosphoprotein binding [GO:0051219]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3uh5a__d1v4wb___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3uhba__d1hbsc___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3uhba__d2uuls___1	Metazoa		Mollusca		cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3uhca__d2uulr___1	Metazoa		Mollusca		cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3uhea__d2d5xb___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	cytoplasm [GO:0005737]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3uhea__d5aqdl___1	Metazoa		Mollusca	Cyanobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3uheb__d2vmli___1	Metazoa		Mollusca	Cyanobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3uhha__d4hswa___1	Metazoa	Metazoa	Mollusca	Annelida	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]			cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d3uhid__d1f99n___1	Metazoa		Mollusca	Rhodophyta	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]	chloroplast thylakoid membrane [GO:0009535]; phycobilisome [GO:0030089]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3uhkb__d3dhrh___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3uhkd__d1y5kb___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3uhlb__d1zj7a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3uhra__d5nb4f___1	Metazoa		Mollusca	Cyanobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3uhtb__d3odqa___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3uhua__d1gh0q___1	Metazoa		Mollusca	Cyanobacteria	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	cytoplasm [GO:0005737]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3uhva__d4dc8a___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3uhvb__d2yrso___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cytoplasm [GO:0005737]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3uhza__d3lb4b___1	Metazoa	Metazoa	Mollusca	Annelida	cytoplasm [GO:0005737]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]			cytoplasm [GO:0005737]		heme binding [GO:0020037]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d3ui4a1_d3kaha2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; preribosome [GO:0030684]; spindle [GO:0005819]; bent DNA binding [GO:0003681]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	rRNA processing [GO:0006364]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; preribosome [GO:0030684]; spindle [GO:0005819]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	bent DNA binding [GO:0003681]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]
d3ui6a1_d2d9fa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; preribosome [GO:0030684]; spindle [GO:0005819]; bent DNA binding [GO:0003681]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; integral component of endoplasmic reticulum membrane [GO:0030176]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; apoptotic process [GO:0006915]; camera-type eye development [GO:0043010]; cell fate specification [GO:0001708]; dorsal/ventral neural tube patterning [GO:0021904]; intracellular signal transduction [GO:0035556]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of BMP signaling pathway [GO:0030513]; smoothened signaling pathway [GO:0007224]; viral process [GO:0016032]	rRNA processing [GO:0006364]	apoptotic process [GO:0006915]; camera-type eye development [GO:0043010]; cell fate specification [GO:0001708]; dorsal/ventral neural tube patterning [GO:0021904]; intracellular signal transduction [GO:0035556]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of BMP signaling pathway [GO:0030513]; smoothened signaling pathway [GO:0007224]; viral process [GO:0016032]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; preribosome [GO:0030684]; spindle [GO:0005819]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; integral component of endoplasmic reticulum membrane [GO:0030176]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	bent DNA binding [GO:0003681]; DNA binding [GO:0003677]; double-stranded DNA binding [GO:0003690]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; RNA binding [GO:0003723]	disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d3ui7a__d3v9bc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d3ui7b__d3sl3a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d3uieb__d6ba6b___1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; plastid [GO:0009536]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; phosphorylation [GO:0016310]; sulfate assimilation [GO:0000103]	azurophil granule membrane [GO:0035577]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein-containing complex binding [GO:0044877]; cell population proliferation [GO:0008283]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gonadotropin-releasing hormone [GO:0097211]; establishment of endothelial barrier [GO:0061028]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of integrin activation [GO:0033625]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; regulation of establishment of cell polarity [GO:2000114]; response to carbohydrate [GO:0009743]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; phosphorylation [GO:0016310]; sulfate assimilation [GO:0000103]	cell population proliferation [GO:0008283]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to gonadotropin-releasing hormone [GO:0097211]; establishment of endothelial barrier [GO:0061028]; interleukin-12-mediated signaling pathway [GO:0035722]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of integrin activation [GO:0033625]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; regulation of establishment of cell polarity [GO:2000114]; response to carbohydrate [GO:0009743]	chloroplast [GO:0009507]; plastid [GO:0009536]	azurophil granule membrane [GO:0035577]; cell-cell junction [GO:0005911]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; lipid droplet [GO:0005811]; membrane [GO:0016020]; plasma membrane [GO:0005886]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein-containing complex binding [GO:0044877]
d3uiva3_d5otbc2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; metal ion binding [GO:0046872]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	extracellular space [GO:0005615]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]
d3uivh3_d2xvva1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3uj2e2_d2gdqa1__1			Firmicutes	Firmicutes	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	glycolytic process [GO:0006096]		cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3uj2h2_d4dhgc2__1			Firmicutes	Actinobacteria	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	metal ion binding [GO:0046872]	glycolytic process [GO:0006096]		cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	metal ion binding [GO:0046872]
d3ujea2_d4h2hb2__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; amino-acid betaine catabolic process [GO:0006579]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	amino-acid betaine catabolic process [GO:0006579]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; racemase activity, acting on amino acids and derivatives [GO:0036361]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d3ujeb1_d1wueb2__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	menaquinone biosynthetic process [GO:0009234]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3ujra1_d3uxkc1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]
d3ujtl1_d3cfkp1__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3ujtl2_d4pj7h1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3ujtl2_d5cipb2__1												
d3ujtm2_d3bh8a1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3uk2b1_d3kt3b___1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]; pantothenate biosynthetic process [GO:0015940]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	pantothenate biosynthetic process [GO:0015940]	tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d3ukda__d2x19a___1		Fungi		Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; magnesium ion binding [GO:0000287]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; UMP kinase activity [GO:0033862]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; CDP biosynthetic process [GO:0046705]; nucleotide salvage [GO:0043173]; pyrimidine nucleobase salvage [GO:0043100]; UDP biosynthetic process [GO:0006225]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nucleus organization [GO:0006997]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein import into nucleus [GO:0006606]; regulation of chromatin silencing at telomere [GO:0031938]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; CDP biosynthetic process [GO:0046705]; nucleotide salvage [GO:0043173]; pyrimidine nucleobase salvage [GO:0043100]; UDP biosynthetic process [GO:0006225]	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nucleus organization [GO:0006997]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein import into nucleus [GO:0006606]; regulation of chromatin silencing at telomere [GO:0031938]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; magnesium ion binding [GO:0000287]; phosphotransferase activity, phosphate group as acceptor [GO:0016776]; UMP kinase activity [GO:0033862]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d3ukrd2_d2p9nf___1	Metazoa	Metazoa	Chordata	Chordata	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	actin filament binding [GO:0051015]	actin filament binding [GO:0051015]
d3uktb__d1db7a3__1	Metazoa		Chordata		integral component of plasma membrane [GO:0005887]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]; potassium ion transmembrane transporter activity [GO:0015079]; voltage-gated potassium channel activity [GO:0005249]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]		potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]		integral component of plasma membrane [GO:0005887]		identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]; potassium ion transmembrane transporter activity [GO:0015079]; voltage-gated potassium channel activity [GO:0005249]	
d3uktc__d5khjb___1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]; potassium ion transmembrane transporter activity [GO:0015079]; voltage-gated potassium channel activity [GO:0005249]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]	axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]; cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; molecular adaptor activity [GO:0060090]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]	cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]	integral component of plasma membrane [GO:0005887]	axon [GO:0030424]; cytoplasm [GO:0005737]; dendrite membrane [GO:0032590]; dendritic shaft [GO:0043198]; HCN channel complex [GO:0098855]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; somatodendritic compartment [GO:0036477]; synapse [GO:0045202]	identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]; potassium ion transmembrane transporter activity [GO:0015079]; voltage-gated potassium channel activity [GO:0005249]	cAMP binding [GO:0030552]; identical protein binding [GO:0042802]; intracellular cAMP-activated cation channel activity [GO:0005222]; molecular adaptor activity [GO:0060090]; PDZ domain binding [GO:0030165]; protein-containing complex binding [GO:0044877]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated sodium channel activity [GO:0005248]
d3ukub__d3djcf1__1	Metazoa		Chordata	Proteobacteria	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]; actin filament binding [GO:0051015]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	Arp2/3 complex-mediated actin nucleation [GO:0034314]	coenzyme A biosynthetic process [GO:0015937]	Arp2/3 protein complex [GO:0005885]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	actin filament binding [GO:0051015]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d3ukvb__d1zrea2__1	Metazoa		Chordata	Proteobacteria	integral component of plasma membrane [GO:0005887]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]; potassium ion transmembrane transporter activity [GO:0015079]; voltage-gated potassium channel activity [GO:0005249]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	integral component of plasma membrane [GO:0005887]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]; potassium ion transmembrane transporter activity [GO:0015079]; voltage-gated potassium channel activity [GO:0005249]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d3ukvc__d1ne4a2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of plasma membrane [GO:0005887]; identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]; potassium ion transmembrane transporter activity [GO:0015079]; voltage-gated potassium channel activity [GO:0005249]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]; cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]	cardiac muscle cell proliferation [GO:0060038]; cGMP-mediated signaling [GO:0019934]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; sarcomere organization [GO:0045214]	integral component of plasma membrane [GO:0005887]	axoneme [GO:0005930]; cAMP-dependent protein kinase complex [GO:0005952]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; immunological synapse [GO:0001772]; neuromuscular junction [GO:0031594]; nucleotide-activated protein kinase complex [GO:0031588]; plasma membrane raft [GO:0044853]	identical protein binding [GO:0042802]; potassium channel activity [GO:0005267]; potassium ion transmembrane transporter activity [GO:0015079]; voltage-gated potassium channel activity [GO:0005249]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP binding [GO:0030552]; cAMP-dependent protein kinase inhibitor activity [GO:0004862]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein kinase A catalytic subunit binding [GO:0034236]; ubiquitin protein ligase binding [GO:0031625]
d3ukyb__d3ftza3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3ukzb__d3q0nb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]; miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]; adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	adult locomotory behavior [GO:0008344]; mRNA destabilization [GO:0061157]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional gene silencing [GO:0016441]; posttranscriptional regulation of gene expression [GO:0010608]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of cell cycle [GO:0051726]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; P-body [GO:0000932]	histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]	miRNA binding [GO:0035198]; mRNA 3'-UTR binding [GO:0003730]; RNA binding [GO:0003723]
d3ul3b__d2hlsa2__1			Apicomplexa	Crenarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; PTEX complex [GO:0097619]; symbiont-containing vacuole [GO:0020003]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; PTEX complex [GO:0097619]; symbiont-containing vacuole [GO:0020003]		oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]	
d3ul5a__d1r4cb___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cysteine-type endopeptidase inhibitor activity [GO:0004869]; identical protein binding [GO:0042802]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; tertiary granule lumen [GO:1904724]; amyloid-beta binding [GO:0001540]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; identical protein binding [GO:0042802]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; cellular protein metabolic process [GO:0044267]; defense response [GO:0006952]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of collagen catabolic process [GO:0010711]; negative regulation of elastin catabolic process [GO:0060311]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]; post-translational protein modification [GO:0043687]; regulation of tissue remodeling [GO:0034103]; supramolecular fiber organization [GO:0097435]		cellular protein metabolic process [GO:0044267]; defense response [GO:0006952]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of collagen catabolic process [GO:0010711]; negative regulation of elastin catabolic process [GO:0060311]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]; post-translational protein modification [GO:0043687]; regulation of tissue remodeling [GO:0034103]; supramolecular fiber organization [GO:0097435]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; tertiary granule lumen [GO:1904724]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; identical protein binding [GO:0042802]	amyloid-beta binding [GO:0001540]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; identical protein binding [GO:0042802]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]
d3ul5d__d1r4cf___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cysteine-type endopeptidase inhibitor activity [GO:0004869]; identical protein binding [GO:0042802]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; tertiary granule lumen [GO:1904724]; amyloid-beta binding [GO:0001540]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; identical protein binding [GO:0042802]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]; cellular protein metabolic process [GO:0044267]; defense response [GO:0006952]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of collagen catabolic process [GO:0010711]; negative regulation of elastin catabolic process [GO:0060311]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]; post-translational protein modification [GO:0043687]; regulation of tissue remodeling [GO:0034103]; supramolecular fiber organization [GO:0097435]		cellular protein metabolic process [GO:0044267]; defense response [GO:0006952]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of collagen catabolic process [GO:0010711]; negative regulation of elastin catabolic process [GO:0060311]; negative regulation of extracellular matrix disassembly [GO:0010716]; negative regulation of peptidase activity [GO:0010466]; negative regulation of proteolysis [GO:0045861]; neutrophil degranulation [GO:0043312]; post-translational protein modification [GO:0043687]; regulation of tissue remodeling [GO:0034103]; supramolecular fiber organization [GO:0097435]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; tertiary granule lumen [GO:1904724]	cysteine-type endopeptidase inhibitor activity [GO:0004869]; identical protein binding [GO:0042802]	amyloid-beta binding [GO:0001540]; cysteine-type endopeptidase inhibitor activity [GO:0004869]; endopeptidase inhibitor activity [GO:0004866]; identical protein binding [GO:0042802]; peptidase inhibitor activity [GO:0030414]; protease binding [GO:0002020]
d3ulda__d4qagb___1			Firmicutes		cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cytoplasm [GO:0005737]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; RNA-DNA hybrid ribonuclease activity [GO:0004523]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3ulfa__d2l0wa___1		Metazoa		Chordata	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; inward rectifier potassium channel complex [GO:1902937]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]; C3HC4-type RING finger domain binding [GO:0055131]; delayed rectifier potassium channel activity [GO:0005251]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]; voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1902282]; cardiac conduction [GO:0061337]; cardiac muscle contraction [GO:0060048]; cellular response to drug [GO:0035690]; membrane depolarization during action potential [GO:0086010]; membrane repolarization [GO:0086009]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; membrane repolarization during ventricular cardiac muscle cell action potential [GO:0098915]; negative regulation of potassium ion export across plasma membrane [GO:1903765]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion export across plasma membrane [GO:0097623]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of heart rate by hormone [GO:0003064]; regulation of membrane potential [GO:0042391]; regulation of membrane repolarization [GO:0060306]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; ventricular cardiac muscle cell action potential [GO:0086005]		cardiac conduction [GO:0061337]; cardiac muscle contraction [GO:0060048]; cellular response to drug [GO:0035690]; membrane depolarization during action potential [GO:0086010]; membrane repolarization [GO:0086009]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; membrane repolarization during ventricular cardiac muscle cell action potential [GO:0098915]; negative regulation of potassium ion export across plasma membrane [GO:1903765]; negative regulation of potassium ion transmembrane transport [GO:1901380]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion export across plasma membrane [GO:0097623]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of heart rate by hormone [GO:0003064]; regulation of membrane potential [GO:0042391]; regulation of membrane repolarization [GO:0060306]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; ventricular cardiac muscle cell action potential [GO:0086005]		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; inward rectifier potassium channel complex [GO:1902937]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; voltage-gated potassium channel complex [GO:0008076]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	C3HC4-type RING finger domain binding [GO:0055131]; delayed rectifier potassium channel activity [GO:0005251]; identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; protein homodimerization activity [GO:0042803]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; voltage-gated potassium channel activity [GO:0005249]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008]; voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1902282]
d3ulfb__d1s1za___1				Proteobacteria	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d3ulfc__d4wlaa___1				Proteobacteria	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]		phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]
d3ulff__d1n9la___1		Viridiplantae		Chlorophyta	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; photoreceptor activity [GO:0009881]; protein serine/threonine kinase activity [GO:0004674]; protein phosphorylation [GO:0006468]; protein-chromophore linkage [GO:0018298]; response to stimulus [GO:0050896]		protein-chromophore linkage [GO:0018298]; protein phosphorylation [GO:0006468]; response to stimulus [GO:0050896]		cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; photoreceptor activity [GO:0009881]; protein serine/threonine kinase activity [GO:0004674]
d3uljb1_d4dami___1	Metazoa		Chordata	Actinobacteria	nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]	single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]		DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]			nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]	single-stranded DNA binding [GO:0003697]
d3umea__d5svuc___1		Viridiplantae	Proteobacteria	Streptophyta	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]; photoreceptor activity [GO:0009881]; circadian rhythm [GO:0007623]; flower development [GO:0009908]; protein ubiquitination [GO:0016567]; protein-chromophore linkage [GO:0018298]; response to blue light [GO:0009637]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	circadian rhythm [GO:0007623]; flower development [GO:0009908]; protein-chromophore linkage [GO:0018298]; protein ubiquitination [GO:0016567]; response to blue light [GO:0009637]		cytosol [GO:0005829]; nucleus [GO:0005634]; SCF ubiquitin ligase complex [GO:0019005]	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	photoreceptor activity [GO:0009881]
d3umgb__d5am1a1__1		Metazoa	Actinobacteria	Chordata	(S)-2-haloacid dehalogenase activity [GO:0018784]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	(S)-2-haloacid dehalogenase activity [GO:0018784]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3umgc__d1rlta___1			Actinobacteria	Proteobacteria	(S)-2-haloacid dehalogenase activity [GO:0018784]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]				cytosol [GO:0005829]	(S)-2-haloacid dehalogenase activity [GO:0018784]	magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; sugar-phosphatase activity [GO:0050308]
d3umgh__d3l1vb___1			Actinobacteria	Proteobacteria	(S)-2-haloacid dehalogenase activity [GO:0018784]	cytosol [GO:0005829]; D,D-heptose 1,7-bisphosphate phosphatase activity [GO:0034200]; magnesium ion binding [GO:0000287]; zinc ion binding [GO:0008270]; ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]		ADP-L-glycero-beta-D-manno-heptose biosynthetic process [GO:0097171]; lipopolysaccharide core region biosynthetic process [GO:0009244]		cytosol [GO:0005829]	(S)-2-haloacid dehalogenase activity [GO:0018784]	D,D-heptose 1,7-bisphosphate phosphatase activity [GO:0034200]; magnesium ion binding [GO:0000287]; zinc ion binding [GO:0008270]
d3umha__d4rd9a___1	Metazoa	Metazoa	Chordata	Chordata	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	basement membrane [GO:0005604]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; alpha-2A adrenergic receptor binding [GO:0031694]; alpha-2B adrenergic receptor binding [GO:0031695]; alpha-2C adrenergic receptor binding [GO:0031696]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cellular response to norepinephrine stimulus [GO:0071874]; endocytosis [GO:0006897]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; nervous system development [GO:0007399]	activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid-beta clearance [GO:1900221]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cellular response to norepinephrine stimulus [GO:0071874]; endocytosis [GO:0006897]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; nervous system development [GO:0007399]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi lumen [GO:0005796]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]	basement membrane [GO:0005604]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]	alpha-2A adrenergic receptor binding [GO:0031694]; alpha-2B adrenergic receptor binding [GO:0031695]; alpha-2C adrenergic receptor binding [GO:0031696]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]
d3umja__d4uuqb___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; acylglycerol lipase activity [GO:0047372]; lysophospholipase activity [GO:0004622]; protein homodimerization activity [GO:0042803]; acylglycerol acyl-chain remodeling [GO:0036155]; acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; monoacylglycerol catabolic process [GO:0052651]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433]		acylglycerol acyl-chain remodeling [GO:0036155]; acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; monoacylglycerol catabolic process [GO:0052651]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]	acylglycerol lipase activity [GO:0047372]; lysophospholipase activity [GO:0004622]; protein homodimerization activity [GO:0042803]
d3umob__d1v1sb___1			Proteobacteria	Deinococcus-Thermus	cytosol [GO:0005829]; 6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphofructokinase activity [GO:0008443]; tagatose-6-phosphate kinase activity [GO:0009024]; cellular response to DNA damage stimulus [GO:0006974]; glycolytic process [GO:0006096]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]; phosphorylation [GO:0016310]	cellular response to DNA damage stimulus [GO:0006974]; glycolytic process [GO:0006096]	phosphorylation [GO:0016310]	cytosol [GO:0005829]		6-phosphofructokinase activity [GO:0003872]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphofructokinase activity [GO:0008443]; tagatose-6-phosphate kinase activity [GO:0009024]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]
d3un8d__d5l5ze___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3un8m__d3dy3z___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3un8o__d1g3in___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	HslUV protease complex [GO:0009376]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein unfolding [GO:0043335]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	protein unfolding [GO:0043335]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	HslUV protease complex [GO:0009376]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; peptidase activity, acting on L-amino acid peptides [GO:0070011]
d3un8v__d4quyx___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3un8w__d4hnza1__1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; HslUV protease complex [GO:0009376]; kinetoplast [GO:0020023]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nuclear lumen [GO:0031981]; proteasome core complex [GO:0005839]; ATP-dependent peptidase activity [GO:0004176]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; mitochondrial DNA inheritance [GO:0033955]; mitochondrial DNA replication [GO:0006264]; proteolysis involved in cellular protein catabolic process [GO:0051603]; rolling circle DNA replication [GO:0070581]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	mitochondrial DNA inheritance [GO:0033955]; mitochondrial DNA replication [GO:0006264]; proteolysis involved in cellular protein catabolic process [GO:0051603]; rolling circle DNA replication [GO:0070581]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; HslUV protease complex [GO:0009376]; kinetoplast [GO:0020023]; mitochondrial nucleoid [GO:0042645]; mitochondrion [GO:0005739]; nuclear lumen [GO:0031981]; proteasome core complex [GO:0005839]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	ATP-dependent peptidase activity [GO:0004176]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3un8x__d4y9yh___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3un8y__d3hyeh___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3un8z__d5laie___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3unb3__d4qw3e___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3unba__d4qv7k___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3unbb__d2iwmc___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	penicillin amidase activity [GO:0008953]; response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	penicillin amidase activity [GO:0008953]
d3unbi__d4y8rl___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3unbs__d5l62j___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3unda1_d3b8dc___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	I band [GO:0031674]; M band [GO:0031430]; fructose-bisphosphate aldolase activity [GO:0004332]; glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	glycolytic process [GO:0006096]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of cell migration [GO:0030335]; protein homotetramerization [GO:0051289]	cytoplasm [GO:0005737]	I band [GO:0031674]; M band [GO:0031430]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	fructose-bisphosphate aldolase activity [GO:0004332]
d3undc1_d2nwsa___1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytoplasm [GO:0005737]; 3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]; keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process [GO:0019294]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]	3-deoxy-8-phosphooctulonate synthase activity [GO:0008676]
d3unfb__d2bjfa___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	choloylglycine hydrolase activity [GO:0045302]	antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	choloylglycine hydrolase activity [GO:0045302]
d3unfd__d1iruq___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]	cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3unfe__d4qz7o___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3unfk__d4qz7g___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3unfl__d1hqyd___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]; protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	protein hexamerization [GO:0034214]; protein unfolding [GO:0043335]; proteolysis [GO:0006508]; response to heat [GO:0009408]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]	cytosol [GO:0005829]; HslUV protease complex [GO:0009376]; membrane [GO:0016020]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; peptidase activity, acting on L-amino acid peptides [GO:0070011]; protein domain specific binding [GO:0019904]
d3unfo__d5l54n___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3unfs__d5l64e___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3unfz__d4qvma___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of endopeptidase activity [GO:0052548]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; proteasome core complex [GO:0005839]; proteasome core complex, beta-subunit complex [GO:0019774]; spermatoproteasome complex [GO:1990111]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3unla__d2xshj___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	steroid metabolic process [GO:0008202]	aromatic compound catabolic process [GO:0019439]			steroid delta-isomerase activity [GO:0004769]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d3unlb__d4nhff___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; protein secretion by the type IV secretion system [GO:0030255]	steroid metabolic process [GO:0008202]	protein secretion by the type IV secretion system [GO:0030255]		integral component of membrane [GO:0016021]	steroid delta-isomerase activity [GO:0004769]	metal ion binding [GO:0046872]
d3unlc__d4bl3a1__1			Proteobacteria	Firmicutes	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	steroid metabolic process [GO:0008202]	response to antibiotic [GO:0046677]		integral component of membrane [GO:0016021]	steroid delta-isomerase activity [GO:0004769]	penicillin binding [GO:0008658]
d3unld__d3vgnb___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	steroid metabolic process [GO:0008202]	steroid metabolic process [GO:0008202]			steroid delta-isomerase activity [GO:0004769]	steroid delta-isomerase activity [GO:0004769]
d3unra__d1l2ea___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]; serine-type endopeptidase activity [GO:0004252]; amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	digestion [GO:0007586]; proteolysis [GO:0006508]	amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d3unxa__d4rydf1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]		cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	extracellular region [GO:0005576]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d3uofc__d5goub___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; intracellular ferritin complex [GO:0008043]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3uofd__d2bk6a1__1			Actinobacteria	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3uofe__d4cmyr___1			Actinobacteria	Chlorobi	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3uoia__d3hx7t___1			Actinobacteria		cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]		response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	
d3uoie__d4am5b___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3uoif__d3isep___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3uoig__d1xmhd___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3uoih__d1z4ah___1			Actinobacteria	Thermotogae	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3uoii__d4bmua___1			Actinobacteria	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d3uoik__d3bvkd1__1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d3uoil__d4cmyh___1			Actinobacteria	Chlorobi	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3uoim__d1j30b___1			Actinobacteria	Crenarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d3uoin__d2g4ha___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3uoiq__d4dyue___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3uoir__d2jd7s___1			Actinobacteria	Euryarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d3uoir__d3ghqf___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3uoiu__d3pw8b___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	phenylacetate catabolic process [GO:0010124]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	
d3uoiv__d3n1za___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d3uoiv__d4toha___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3uoiw__d1mfrj___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3uoix__d1f30c___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	response to iron ion [GO:0010039]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3uorb__d3mz9a___1			Proteobacteria	Proteobacteria		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]; negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]		negative chemotaxis [GO:0050919]; nickel cation transport [GO:0015675]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		heme binding [GO:0020037]; metal cluster binding [GO:0051540]; nickel cation binding [GO:0016151]; peptide transmembrane transporter activity [GO:1904680]; transition metal ion binding [GO:0046914]
d3upaa__d2g2ra2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; immunoglobulin complex [GO:0019814]	antigen binding [GO:0003823]	
d3upab__d1mqkl___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3upca__d1d6vh1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3upcd__d1naml1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3upce__d5ja8h1__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3upcg__d1rivl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3upda1_d2h3ec1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d3upda2_d1fb5a1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; ammonia homeostasis [GO:0097272]; arginine biosynthetic process [GO:0006526]; citrulline biosynthetic process [GO:0019240]; ornithine catabolic process [GO:0006593]; urea cycle [GO:0000050]	arginine biosynthetic process [GO:0006526]	ammonia homeostasis [GO:0097272]; arginine biosynthetic process [GO:0006526]; citrulline biosynthetic process [GO:0019240]; ornithine catabolic process [GO:0006593]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]	mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d3upea__d5c67a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi lumen [GO:0005796]; Golgi-associated vesicle [GO:0005798]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]; acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of T cell migration [GO:2000406]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid-beta clearance [GO:1900221]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	digestion [GO:0007586]; proteolysis [GO:0006508]	activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adult locomotory behavior [GO:0008344]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; associative learning [GO:0008306]; astrocyte activation [GO:0048143]; astrocyte activation involved in immune response [GO:0002265]; axo-dendritic transport [GO:0008088]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; calcium-mediated signaling [GO:0019722]; cell adhesion [GO:0007155]; cellular copper ion homeostasis [GO:0006878]; cellular process [GO:0009987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to cAMP [GO:0071320]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to norepinephrine stimulus [GO:0071874]; cholesterol metabolic process [GO:0008203]; cognition [GO:0050890]; collateral sprouting in absence of injury [GO:0048669]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; dendrite development [GO:0016358]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning [GO:0007612]; learning or memory [GO:0007611]; lipoprotein metabolic process [GO:0042157]; locomotory behavior [GO:0007626]; mating behavior [GO:0007617]; memory [GO:0007613]; microglia development [GO:0014005]; microglial cell activation [GO:0001774]; modulation of age-related behavioral decline [GO:0090647]; modulation of excitatory postsynaptic potential [GO:0098815]; mRNA polyadenylation [GO:0006378]; negative regulation of blood circulation [GO:1903523]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; neuron projection development [GO:0031175]; neuron projection maintenance [GO:1990535]; neuron remodeling [GO:0016322]; Notch signaling pathway [GO:0007219]; platelet degranulation [GO:0002576]; positive regulation of 1-phosphatidylinositol-3-kinase activity [GO:0061903]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of apoptotic process [GO:0043065]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell activation [GO:0050867]; positive regulation of cellular response to thapsigargin [GO:1905893]; positive regulation of cellular response to tunicamycin [GO:1905896]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelin secretion [GO:1904472]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of G protein-coupled receptor internalization [GO:1904022]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of histone acetylation [GO:0035066]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta biosynthetic process [GO:0050725]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JNK cascade [GO:0046330]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import [GO:1904591]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor binding [GO:1900122]; positive regulation of response to endoplasmic reticulum stress [GO:1905898]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; post-translational protein modification [GO:0043687]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; protein trimerization [GO:0070206]; regulation of acetylcholine-gated cation channel activity [GO:1903048]; regulation of amyloid-beta clearance [GO:1900221]; regulation of amyloid fibril formation [GO:1905906]; regulation of dendritic spine maintenance [GO:1902950]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; regulation of gene expression [GO:0010468]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multicellular organism growth [GO:0040014]; regulation of NMDA receptor activity [GO:2000310]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of presynapse assembly [GO:1905606]; regulation of response to calcium ion [GO:1905945]; regulation of spontaneous synaptic transmission [GO:0150003]; regulation of synapse structure or activity [GO:0050803]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of translation [GO:0006417]; regulation of Wnt signaling pathway [GO:0030111]; response to interleukin-1 [GO:0070555]; response to lead ion [GO:0010288]; response to oxidative stress [GO:0006979]; response to yeast [GO:0001878]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; suckling behavior [GO:0001967]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; tumor necrosis factor production [GO:0032640]; visual learning [GO:0008542]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	amyloid-beta complex [GO:0106003]; apical part of cell [GO:0045177]; astrocyte projection [GO:0097449]; axon [GO:0030424]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; ciliary rootlet [GO:0035253]; clathrin-coated pit [GO:0005905]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome lumen [GO:0031904]; endosome to plasma membrane transport vesicle [GO:0070381]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle [GO:0005798]; Golgi lumen [GO:0005796]; growth cone filopodium [GO:1990812]; growth cone lamellipodium [GO:1990761]; high-density lipoprotein particle [GO:0034364]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; intermediate-density lipoprotein particle [GO:0034363]; lipoprotein particle [GO:1990777]; main axon [GO:0044304]; membrane [GO:0016020]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear envelope lumen [GO:0005641]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; presynaptic active zone [GO:0048786]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; recycling endosome [GO:0055037]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; spindle midzone [GO:0051233]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network membrane [GO:0032588]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	acetylcholine receptor activator activity [GO:0030549]; acetylcholine receptor binding [GO:0033130]; amylin binding [GO:0097645]; apolipoprotein binding [GO:0034185]; chaperone binding [GO:0051087]; chemoattractant activity [GO:0042056]; DNA binding [GO:0003677]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; frizzled binding [GO:0005109]; G protein-coupled receptor binding [GO:0001664]; growth factor receptor binding [GO:0070851]; heparan sulfate binding [GO:1904399]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; peptidase activator activity [GO:0016504]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; PTB domain binding [GO:0051425]; RAGE receptor binding [GO:0050786]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; serine-type endopeptidase inhibitor activity [GO:0004867]; signaling receptor activator activity [GO:0030546]; signaling receptor binding [GO:0005102]; transition metal ion binding [GO:0046914]
d3upjb__d5p35a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3upqa1_d9icya1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d3upra1_d3m1ba1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3uprb__d1cbvh2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	metal ion binding [GO:0046872]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]
d3uprc1_d4pjic1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3uprc2_d3utzd2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3uprd__d2zolb___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3uq0a1_d4i2ca1__1	Metazoa	Metazoa	Chordata	Chordata	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3uq1a1_d4qzba1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]		base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3uq2a3_d1no5a___1	Metazoa		Chordata	Proteobacteria	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	nucleotidyltransferase activity [GO:0016779]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]		nucleoplasm [GO:0005654]; nucleus [GO:0005634]		5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]	nucleotidyltransferase activity [GO:0016779]
d3uq6a__d2fv7b___1	Metazoa	Metazoa	Platyhelminthes	Chordata	adenosine kinase activity [GO:0004001]; nucleotide binding [GO:0000166]; purine ribonucleoside salvage [GO:0006166]	cytosol [GO:0005829]; nucleus [GO:0005634]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]	purine ribonucleoside salvage [GO:0006166]	D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098]		cytosol [GO:0005829]; nucleus [GO:0005634]	adenosine kinase activity [GO:0004001]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d3uq9a__d1v1bb___1	Metazoa		Platyhelminthes	Deinococcus-Thermus	adenosine kinase activity [GO:0004001]; nucleotide binding [GO:0000166]; purine ribonucleoside salvage [GO:0006166]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]; phosphorylation [GO:0016310]	purine ribonucleoside salvage [GO:0006166]	phosphorylation [GO:0016310]			adenosine kinase activity [GO:0004001]; nucleotide binding [GO:0000166]	2-dehydro-3-deoxygluconokinase activity [GO:0008673]; ATP binding [GO:0005524]; nucleotide binding [GO:0000166]
d3uqia__d3praa___1	Metazoa		Arthropoda	Euryarchaeota	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]					peptidyl-prolyl cis-trans isomerase activity [GO:0003755]	peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d3uqnb__d3lbmc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; 4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]; diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	4-hydroxy-tetrahydrodipicolinate synthase activity [GO:0008840]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]
d3uqoa__d1sgye___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase inhibitor activity [GO:0004867]
d3uqva__d4abaa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3ur7a1_d3muaa___1	Viridiplantae		Streptophyta	Firmicutes	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]			glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]	endo-1,4-beta-xylanase activity [GO:0031176]
d3ureb__d1cqqa___1			Proteobacteria		extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3urmb__d1lbhc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; chemotaxis [GO:0006935]	cytosol [GO:0005829]; bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]; negative regulation of transcription, DNA-templated [GO:0045892]	chemotaxis [GO:0006935]	negative regulation of transcription, DNA-templated [GO:0045892]	periplasmic space [GO:0042597]	cytosol [GO:0005829]		bacterial-type proximal promoter sequence-specific DNA binding [GO:0000986]; DNA-binding transcription repressor activity [GO:0001217]; identical protein binding [GO:0042802]
d3urpa__d5hoha___1	Fungi	Fungi	Ascomycota	Ascomycota	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	cell septum [GO:0030428]; hyphal tip [GO:0001411]; endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]			cell septum [GO:0030428]; hyphal tip [GO:0001411]	cell septum [GO:0030428]; hyphal tip [GO:0001411]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]	endoribonuclease activity [GO:0004521]; ribonuclease T1 activity [GO:0046589]; RNA binding [GO:0003723]
d3urra1_d1a3ab___1			Proteobacteria	Proteobacteria	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity [GO:0022872]; protein-phosphocysteine-mannitol phosphotransferase system transporter activity [GO:0090565]; mannitol transport [GO:0015797]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	mannitol transport [GO:0015797]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]		integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [GO:0008982]	kinase activity [GO:0016301]; protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity [GO:0022872]; protein-phosphocysteine-mannitol phosphotransferase system transporter activity [GO:0090565]
d3urya2_d3owel2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	extracellular region [GO:0005576]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	extracellular region [GO:0005576]	extracellular region [GO:0005576]		
d3us0a1_d1rama2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; rough endoplasmic reticulum [GO:0005791]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; WW domain binding [GO:0050699]; apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative cell aging [GO:0001302]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]; actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative cell aging [GO:0001302]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; cellular response to angiotensin [GO:1904385]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to nicotine [GO:0071316]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; chromatin organization [GO:0006325]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; hair follicle development [GO:0001942]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; postsynapse to nucleus signaling pathway [GO:0099527]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of inflammatory response [GO:0050727]; regulation of NIK/NF-kappaB signaling [GO:1901222]; regulation of transcription, DNA-templated [GO:0006355]; response to amino acid [GO:0043200]; response to bacterium [GO:0009617]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to cytokine [GO:0034097]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; rough endoplasmic reticulum [GO:0005791]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; NF-kappaB complex [GO:0071159]; NF-kappaB p50/p65 complex [GO:0035525]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; transcription factor complex [GO:0005667]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; WW domain binding [GO:0050699]	actinin binding [GO:0042805]; activating transcription factor binding [GO:0033613]; ankyrin repeat binding [GO:0071532]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NF-kappaB binding [GO:0051059]; phosphate ion binding [GO:0042301]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; repressing transcription factor binding [GO:0070491]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]
d3us0c1_d1leia2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; rough endoplasmic reticulum [GO:0005791]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; WW domain binding [GO:0050699]; apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative cell aging [GO:0001302]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; cranial skeletal system development [GO:1904888]; ectoderm and mesoderm interaction [GO:0007499]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; multicellular organism aging [GO:0010259]; negative regulation of cellular senescence [GO:2000773]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of somatic stem cell population maintenance [GO:1904674]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative cell aging [GO:0001302]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; rough endoplasmic reticulum [GO:0005791]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; double-stranded DNA binding [GO:0003690]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; WW domain binding [GO:0050699]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3us3a2_d1gnwa2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of store-operated calcium channel activity [GO:1901341]; protein polymerization [GO:0051258]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of store-operated calcium entry [GO:2001256]; sarcomere organization [GO:0045214]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of store-operated calcium channel activity [GO:1901341]; protein polymerization [GO:0051258]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of store-operated calcium entry [GO:2001256]; sarcomere organization [GO:0045214]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d3ussb__d4yyoa___1		Metazoa	Proteobacteria	Chordata	ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	oxidation-reduction process [GO:0055114]	cysteine metabolic process [GO:0006534]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]		cytosol [GO:0005829]	ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d3usxb__d2y2ec___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of cytokine production [GO:0001818]; peptidoglycan catabolic process [GO:0009253]	cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]	cytoplasm [GO:0005737]	N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]; peptidoglycan binding [GO:0042834]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; N-acetylmuramoyl-L-alanine amidase activity [GO:0008745]
d3ut2a2_d2xj8a1__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3utla__d2r5qc___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; multivesicular body lumen [GO:0097486]; aspartic-type endopeptidase activity [GO:0004190]; cellular protein metabolic process [GO:0044267]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	cellular protein metabolic process [GO:0044267]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular exosome [GO:0070062]; multivesicular body lumen [GO:0097486]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3utpe1_d4h8wl1__1						host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]		host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		structural molecule activity [GO:0005198]
d3utpe2_d4pjdh1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3utpk1_d4yxkl2__1		Metazoa		Chordata		anchored component of membrane [GO:0031225]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; protein homooligomerization [GO:0051260]		protein homooligomerization [GO:0051260]		anchored component of membrane [GO:0031225]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]		copper ion binding [GO:0005507]
d3utpk2_d1vesa___1		Metazoa		Chordata								
d3utpl2_d1oaqh___1		Metazoa		Chordata		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]		extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]		
d3utsb1_d1ynkl2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3utsg1_d1emtl1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3uttb1_d1gm3h1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3utze2_d5u1rb1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3uugb__d3h6gb___1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; chemotaxis [GO:0006935]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	chemotaxis [GO:0006935]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	periplasmic space [GO:0042597]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]		extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]
d3uuza__d1c2da___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3uv4b1_d5fe2a___1	Metazoa	Metazoa	Chordata	Chordata	MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]; ATP binding [GO:0005524]; histone acetyltransferase activity [GO:0004402]; kinase activity [GO:0016301]; lysine-acetylated histone binding [GO:0070577]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein heterodimerization activity [GO:0046982]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin conjugating enzyme activity [GO:0061631]; cell cycle [GO:0007049]; cellular response to ATP [GO:0071318]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA-templated transcription, initiation [GO:0006352]; midbrain development [GO:0030901]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of protein autoubiquitination [GO:1905524]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010768]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription initiation from RNA polymerase II promoter [GO:0060260]; regulation of transcription, DNA-templated [GO:0006355]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription factor catabolic process [GO:0036369]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cell cycle [GO:0007049]; cellular response to ATP [GO:0071318]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA-templated transcription, initiation [GO:0006352]; midbrain development [GO:0030901]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of protein autoubiquitination [GO:1905524]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010768]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription initiation from RNA polymerase II promoter [GO:0060260]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription factor catabolic process [GO:0036369]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; histone acetyltransferase activity [GO:0004402]; kinase activity [GO:0016301]; lysine-acetylated histone binding [GO:0070577]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein heterodimerization activity [GO:0046982]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin conjugating enzyme activity [GO:0061631]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]
d3uv5a1_d5fe6b___1	Metazoa	Metazoa	Chordata	Chordata	MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]; ATP binding [GO:0005524]; histone acetyltransferase activity [GO:0004402]; kinase activity [GO:0016301]; lysine-acetylated histone binding [GO:0070577]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein heterodimerization activity [GO:0046982]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin conjugating enzyme activity [GO:0061631]; cell cycle [GO:0007049]; cellular response to ATP [GO:0071318]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA-templated transcription, initiation [GO:0006352]; midbrain development [GO:0030901]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of protein autoubiquitination [GO:1905524]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010768]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription initiation from RNA polymerase II promoter [GO:0060260]; regulation of transcription, DNA-templated [GO:0006355]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription factor catabolic process [GO:0036369]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cell cycle [GO:0007049]; cellular response to ATP [GO:0071318]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA-templated transcription, initiation [GO:0006352]; midbrain development [GO:0030901]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of protein autoubiquitination [GO:1905524]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010768]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription initiation from RNA polymerase II promoter [GO:0060260]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription factor catabolic process [GO:0036369]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; histone acetyltransferase activity [GO:0004402]; kinase activity [GO:0016301]; lysine-acetylated histone binding [GO:0070577]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein heterodimerization activity [GO:0046982]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin conjugating enzyme activity [GO:0061631]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]
d3uv5a1_d5pgga1__1	Metazoa	Metazoa	Chordata	Chordata	MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]; ATP binding [GO:0005524]; histone acetyltransferase activity [GO:0004402]; kinase activity [GO:0016301]; lysine-acetylated histone binding [GO:0070577]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein heterodimerization activity [GO:0046982]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin conjugating enzyme activity [GO:0061631]; cell cycle [GO:0007049]; cellular response to ATP [GO:0071318]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA-templated transcription, initiation [GO:0006352]; midbrain development [GO:0030901]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of protein autoubiquitination [GO:1905524]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010768]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription initiation from RNA polymerase II promoter [GO:0060260]; regulation of transcription, DNA-templated [GO:0006355]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription factor catabolic process [GO:0036369]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	cell cycle [GO:0007049]; cellular response to ATP [GO:0071318]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA-templated transcription, initiation [GO:0006352]; midbrain development [GO:0030901]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of gene expression [GO:0010629]; negative regulation of protein autoubiquitination [GO:1905524]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010768]; negative regulation of ubiquitin-dependent protein catabolic process [GO:2000059]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription initiation from RNA polymerase II promoter [GO:0060260]; RNA polymerase II preinitiation complex assembly [GO:0051123]; transcription by RNA polymerase II [GO:0006366]; transcription factor catabolic process [GO:0036369]; transcription initiation from RNA polymerase II promoter [GO:0006367]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	MLL1 complex [GO:0071339]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcription factor TFIID complex [GO:0005669]	nucleus [GO:0005634]	ATP binding [GO:0005524]; histone acetyltransferase activity [GO:0004402]; kinase activity [GO:0016301]; lysine-acetylated histone binding [GO:0070577]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; protein heterodimerization activity [GO:0046982]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; RNA polymerase II-specific DNA-binding transcription factor binding [GO:0061629]; sequence-specific DNA binding [GO:0043565]; TBP-class protein binding [GO:0017025]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; ubiquitin conjugating enzyme activity [GO:0061631]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d3uvcb1_d3dpfb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	collagen catabolic process [GO:0030574]; endodermal cell differentiation [GO:0035987]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of gene expression [GO:0010629]; negative regulation of interleukin-10 production [GO:0032693]; neutrophil degranulation [GO:0043312]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of tumor necrosis factor secretion [GO:1904469]; proteolysis [GO:0006508]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	collagen-containing extracellular matrix [GO:0062023]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d3uvea__d1iy8g___1			Actinobacteria	Actinobacteria	(+)-trans-carveol dehydrogenase activity [GO:0033702]; nucleotide binding [GO:0000166]	oxidoreductase activity [GO:0016491]					(+)-trans-carveol dehydrogenase activity [GO:0033702]; nucleotide binding [GO:0000166]	oxidoreductase activity [GO:0016491]
d3uvhb1_d3tjfa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; 4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; I-kappaB phosphorylation [GO:0007252]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; neutrophil degranulation [GO:0043312]; protein maturation by protein folding [GO:0022417]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cell [GO:0005623]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; smooth endoplasmic reticulum [GO:0005790]	cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d3uvhb2_d4ecbb1__1	Metazoa	Metazoa	Chordata	Platyhelminthes	blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]	glutathione transferase activity [GO:0004364]	chloride transport [GO:0006821]; platelet aggregation [GO:0070527]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell cycle [GO:0051726]; regulation of ion transmembrane transport [GO:0034765]; regulation of mitochondrial membrane potential [GO:0051881]; signal transduction [GO:0007165]		blood microparticle [GO:0072562]; brush border [GO:0005903]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]		cadherin binding [GO:0045296]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]	glutathione transferase activity [GO:0004364]
d3uvtc1_d1m2da___1	Metazoa		Chordata	Aquificae	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; isomerase activity [GO:0016853]; apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	oxidation-reduction process [GO:0055114]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]		isomerase activity [GO:0016853]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]
d3uvtc1_d5eclb1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; isomerase activity [GO:0016853]; apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	isomerase activity [GO:0016853]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d3uvtd1_d2h1bc___1	Metazoa		Chordata	Firmicutes	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; isomerase activity [GO:0016853]; apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]	cell [GO:0005623]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	isomerase activity [GO:0016853]	antioxidant activity [GO:0016209]; disulfide oxidoreductase activity [GO:0015036]
d3uvxa1_d5uf0a1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]
d3uw8a1_d5ciec___1		Fungi	Euryarchaeota	Ascomycota	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3uw8b1_d2b12a___1		Fungi	Euryarchaeota	Ascomycota	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3uw8b2_d3hdla___1		Viridiplantae	Euryarchaeota	Streptophyta	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]		extracellular region [GO:0005576]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3uwna1_d2ri5a2__1	Metazoa	Metazoa	Chordata	Chordata	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]; chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]; chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	chromatin [GO:0000785]; condensed chromosome [GO:0000793]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; histone binding [GO:0042393]; identical protein binding [GO:0042802]; methylated histone binding [GO:0035064]; nucleosomal histone binding [GO:0031493]; nucleosome binding [GO:0031491]; SAM domain binding [GO:0032093]; zinc ion binding [GO:0008270]
d3uwva1_d4pcfc___1			Firmicutes		cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d3uwwb__d2yc8d___1			Firmicutes		cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]		cytoplasm [GO:0005737]		triose-phosphate isomerase activity [GO:0004807]	
d3uwya1_d4obtb1__1		Viridiplantae	Firmicutes	Streptophyta	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	apoplast [GO:0048046]; cell wall [GO:0005618]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuolar membrane [GO:0005774]; vacuole [GO:0005773]; copper ion binding [GO:0005507]; triose-phosphate isomerase activity [GO:0004807]; cellular carbohydrate metabolic process [GO:0044262]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; response to cadmium ion [GO:0046686]; response to zinc ion [GO:0010043]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	cellular carbohydrate metabolic process [GO:0044262]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; response to cadmium ion [GO:0046686]; response to zinc ion [GO:0010043]	cytoplasm [GO:0005737]	apoplast [GO:0048046]; cell wall [GO:0005618]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuolar membrane [GO:0005774]; vacuole [GO:0005773]	triose-phosphate isomerase activity [GO:0004807]	copper ion binding [GO:0005507]; triose-phosphate isomerase activity [GO:0004807]
d3ux7h__d4dbka___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]; bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	arachidonic acid secretion [GO:0050482]; lipid catabolic process [GO:0016042]; phospholipid metabolic process [GO:0006644]	activation of MAPK activity [GO:0000187]; cellular response to insulin stimulus [GO:0032869]; fatty acid biosynthetic process [GO:0006633]; interleukin-8 production [GO:0032637]; intracellular signal transduction [GO:0035556]; leukotriene biosynthetic process [GO:0019370]; lipid catabolic process [GO:0016042]; neutrophil chemotaxis [GO:0030593]; neutrophil mediated immunity [GO:0002446]; phospholipid metabolic process [GO:0006644]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune response [GO:0050778]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of glucose import [GO:0046324]	extracellular region [GO:0005576]	cell [GO:0005623]; cell surface [GO:0009986]; extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]	bile acid binding [GO:0032052]; calcium ion binding [GO:0005509]; phospholipase A2 activity [GO:0004623]; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) [GO:0102567]; phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) [GO:0102568]; signaling receptor binding [GO:0005102]
d3ux9b1_d3duua___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]		adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]	
d3ux9d1_d1y18a2__1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]		adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]		extracellular region [GO:0005576]; extracellular space [GO:0005615]		cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]	
d3ux9d1_d3bwaa1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]; adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; B cell proliferation [GO:0042100]; blood coagulation [GO:0007596]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; humoral immune response [GO:0006959]; natural killer cell activation involved in immune response [GO:0002323]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; response to exogenous dsRNA [GO:0043330]; T cell activation involved in immune response [GO:0002286]; type I interferon signaling pathway [GO:0060337]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytokine activity [GO:0005125]; type I interferon receptor binding [GO:0005132]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3uxeb__d1dxqc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; superoxide dismutase activity [GO:0004784]
d3uxeb__d1ycgd1__1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]		chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d3uxha__d1d4ac___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]; memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]; aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	memory [GO:0007613]; oxidation-reduction process [GO:0055114]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; xenobiotic metabolic process [GO:0006805]	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to metal ion [GO:0071248]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of cellular amino acid metabolic process [GO:0006521]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hydrogen sulfide [GO:1904880]; response to nitrogen compound [GO:1901698]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; synaptic transmission, cholinergic [GO:0007271]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; synapse [GO:0045202]	chloride ion binding [GO:0031404]; dihydronicotinamide riboside quinone reductase activity [GO:0001512]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; melatonin binding [GO:1904408]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; protein homodimerization activity [GO:0042803]; resveratrol binding [GO:1905594]; zinc ion binding [GO:0008270]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; NAD(P)H dehydrogenase (quinone) activity [GO:0003955]; oxidoreductase activity [GO:0016491]; RNA binding [GO:0003723]; superoxide dismutase activity [GO:0004784]
d3uxlb1_d1sjbb2__1			Proteobacteria	Actinobacteria	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	menaquinone biosynthetic process [GO:0009234]			mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3uxlc2_d4g8tc2__1			Proteobacteria	Proteobacteria	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; glucarate catabolic process [GO:0019394]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	glucarate catabolic process [GO:0019394]			mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3uxld1_d4ihcf1__1			Proteobacteria	Proteobacteria	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]			mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]	gluconate dehydratase activity [GO:0047929]; magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]
d3uxld2_d1l8pd1__1		Fungi	Proteobacteria	Ascomycota	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]; cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cellular amino acid catabolic process [GO:0009063]; mandelate catabolic process [GO:0019596]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	mandelate racemase activity [GO:0018838]; metal ion binding [GO:0046872]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3uxmd__d1z0ka1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	anchored component of synaptic vesicle membrane [GO:0098993]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; insulin-responsive compartment [GO:0032593]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic recycling endosome [GO:0098837]; recycling endosome membrane [GO:0055038]; vesicle [GO:0031982]; ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; ionotropic glutamate receptor binding [GO:0035255]; syntaxin binding [GO:0019905]; antigen processing and presentation [GO:0019882]; intracellular protein transport [GO:0006886]; phosphatidylinositol biosynthetic process [GO:0006661]; Rab protein signal transduction [GO:0032482]; regulation of endocytosis [GO:0030100]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]	antigen processing and presentation [GO:0019882]; intracellular protein transport [GO:0006886]; phosphatidylinositol biosynthetic process [GO:0006661]; Rab protein signal transduction [GO:0032482]; regulation of endocytosis [GO:0030100]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	anchored component of synaptic vesicle membrane [GO:0098993]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; insulin-responsive compartment [GO:0032593]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic recycling endosome [GO:0098837]; recycling endosome membrane [GO:0055038]; vesicle [GO:0031982]	ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; uridylate kinase activity [GO:0009041]	ATPase activator activity [GO:0001671]; ATPase binding [GO:0051117]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; ionotropic glutamate receptor binding [GO:0035255]; syntaxin binding [GO:0019905]
d3uxoa1_d4qzfa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA nucleotidylexotransferase activity [GO:0003912]; DNA-directed DNA polymerase activity [GO:0003887]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ATP [GO:0033198]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; euchromatin [GO:0000791]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA nucleotidylexotransferase activity [GO:0003912]; hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d3uxoa3_d3mbya3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d3uxob1_d2bcua1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	5'-deoxyribose-5-phosphate lyase activity [GO:0051575]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]
d3uypa2_d3u4bl1__1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	
d3uzea2_d5tgbb1__1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	
d3uzeb2_d3oxsb1__1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3uzqb__d7cgta1__1				Firmicutes	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3uzua__d4e32a___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity [GO:0052908]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]	metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]			cytoplasm [GO:0005737]		16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity [GO:0052908]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]	metal ion binding [GO:0046872]; methyltransferase activity [GO:0008168]
d3uzvb2_d1kb5l1__1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3uzya__d2nvda___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]; C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; C21-steroid hormone metabolic process [GO:0008207]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	C21-steroid hormone biosynthetic process [GO:0006700]; carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular response to methylglyoxal [GO:0097238]; cellular response to peptide [GO:1901653]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; fructose biosynthetic process [GO:0046370]; inner medullary collecting duct development [GO:0072061]; maternal process involved in female pregnancy [GO:0060135]; metanephric collecting duct development [GO:0072205]; naphthalene metabolic process [GO:0018931]; negative regulation of apoptotic process [GO:0043066]; norepinephrine metabolic process [GO:0042415]; oxidation-reduction process [GO:0055114]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of urine volume [GO:0035809]; renal water homeostasis [GO:0003091]; response to thyroid hormone [GO:0097066]; response to water deprivation [GO:0009414]; retinoid metabolic process [GO:0001523]; sorbitol biosynthetic process [GO:0006061]; stress-activated protein kinase signaling cascade [GO:0031098]; tissue homeostasis [GO:0001894]	cytosol [GO:0005829]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; mast cell granule [GO:0042629]; nucleoplasm [GO:0005654]; paranodal junction [GO:0033010]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane bounded cell projection cytoplasm [GO:0032838]; Schmidt-Lanterman incisure [GO:0043220]; Schwann cell microvillus [GO:0097454]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; ketosteroid monooxygenase activity [GO:0047086]; oxidoreductase activity [GO:0016491]; steroid binding [GO:0005496]; steroid dehydrogenase activity [GO:0016229]	alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; allyl-alcohol dehydrogenase activity [GO:0047655]; electron transfer activity [GO:0009055]; glyceraldehyde oxidoreductase activity [GO:0043795]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; retinal dehydrogenase activity [GO:0001758]
d3v03a3_d5id7a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3v03b1_d2bxqa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3v03b1_d2xw1a3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3v03b2_d1uora1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3v08a3_d5ij5a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3v09a2_d2esgc2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; metal ion binding [GO:0046872]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; metal ion binding [GO:0046872]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3v09a3_d1kxpd2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; metal ion binding [GO:0046872]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; metal ion binding [GO:0046872]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3v09a3_d2bxka1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; metal ion binding [GO:0046872]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular response to starvation [GO:0009267]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; fatty acid binding [GO:0005504]; metal ion binding [GO:0046872]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d3v0nb1_d1h5ta___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	cytosol [GO:0005829]; glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; O antigen biosynthetic process [GO:0009243]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	cytosol [GO:0005829]	antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3v0oa__d2vs3b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d3v0vb2_d2dlia2__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; regulation of immune response [GO:0050776]		regulation of immune response [GO:0050776]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		
d3v0vl2_d4ku1b2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3v0wl1_d4tscl2__1		Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]		beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3v0wl2_d1q9la1__1												
d3v13a__d4ylud___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of host autophagy [GO:0039520]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; zinc ion binding [GO:0008270]
d3v15c__d1os7a___1			Proteobacteria	Proteobacteria	dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]	cytoplasm [GO:0005737]; L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]; sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]		sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]		cytoplasm [GO:0005737]	dioxygenase activity [GO:0051213]; identical protein binding [GO:0042802]	L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]
d3v1ka__d2pu5a___1			Proteobacteria	Proteobacteria	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; aromatic compound catabolic process [GO:0019439]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]	aromatic compound catabolic process [GO:0019439]			2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]
d3v1kb__d2wg2a___1		Metazoa	Proteobacteria	Chordata	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]; aromatic compound catabolic process [GO:0019439]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	aromatic compound catabolic process [GO:0019439]	acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity [GO:0018771]	acetylcholinesterase activity [GO:0003990]
d3v1wa1_d3qfbd1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of store-operated calcium channel activity [GO:1901341]; protein polymerization [GO:0051258]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of store-operated calcium entry [GO:2001256]; sarcomere organization [GO:0045214]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]; activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of store-operated calcium channel activity [GO:1901341]; protein polymerization [GO:0051258]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of store-operated calcium entry [GO:2001256]; sarcomere organization [GO:0045214]	activation of protein kinase B activity [GO:0032148]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oxidation-reduction process [GO:0055114]; positive regulation of DNA binding [GO:0043388]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; response to radiation [GO:0009314]	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]	peptide disulfide oxidoreductase activity [GO:0015037]; protein disulfide oxidoreductase activity [GO:0015035]; RNA binding [GO:0003723]; thioredoxin-disulfide reductase activity [GO:0004791]
d3v1wa3_d4mh3h___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]; calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of store-operated calcium channel activity [GO:1901341]; protein polymerization [GO:0051258]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of store-operated calcium entry [GO:2001256]; sarcomere organization [GO:0045214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of store-operated calcium channel activity [GO:1901341]; protein polymerization [GO:0051258]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; regulation of store-operated calcium entry [GO:2001256]; sarcomere organization [GO:0045214]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]; mitochondrial matrix [GO:0005759]; sarcoplasmic reticulum [GO:0016529]; sarcoplasmic reticulum lumen [GO:0033018]; sarcoplasmic reticulum membrane [GO:0033017]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; metal ion binding [GO:0046872]; potassium ion binding [GO:0030955]; protein homodimerization activity [GO:0042803]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d3v1zb__d1knva___1			Firmicutes	Firmicutes	endonuclease activity [GO:0004519]	endonuclease activity [GO:0004519]					endonuclease activity [GO:0004519]	endonuclease activity [GO:0004519]
d3v21g__d3zefb2__1		Fungi	Firmicutes	Ascomycota	endonuclease activity [GO:0004519]	catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]; generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]		generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA 5'-splice site recognition [GO:0000395]; spliceosomal tri-snRNP complex assembly [GO:0000244]		catalytic step 2 spliceosome [GO:0071013]; nucleus [GO:0005634]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	endonuclease activity [GO:0004519]	mRNA binding [GO:0003729]; pre-mRNA intronic binding [GO:0097157]; second spliceosomal transesterification activity [GO:0000386]; U1 snRNA binding [GO:0030619]; U2 snRNA binding [GO:0030620]; U5 snRNA binding [GO:0030623]; U6 snRNA binding [GO:0017070]
d3v26x__d1imua___1				Proteobacteria		cytosolic small ribosomal subunit [GO:0022627]; ribosomal small subunit binding [GO:0043024]; ribosome binding [GO:0043022]; negative regulation of translational elongation [GO:0045900]; primary metabolic process [GO:0044238]		negative regulation of translational elongation [GO:0045900]; primary metabolic process [GO:0044238]		cytosolic small ribosomal subunit [GO:0022627]		ribosomal small subunit binding [GO:0043024]; ribosome binding [GO:0043022]
d3v2cy__d3v28x___1												
d3v2ey__d4fylb1__1												
d3v2la1_d2erba___1	Metazoa	Metazoa	Arthropoda	Arthropoda	extracellular region [GO:0005576]; dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]	odorant binding [GO:0005549]	olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]		extracellular region [GO:0005576]		dibutyl phthalate binding [GO:0035275]; diphenyl phthalate binding [GO:0035274]; odorant binding [GO:0005549]	odorant binding [GO:0005549]
d3v3fa__d4knnb___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; myelin sheath [GO:0043209]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	bicarbonate transport [GO:0015701]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; myelin sheath [GO:0043209]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3v3hb__d3ks3a___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3v3ja__d3tvnx___1	Metazoa	Metazoa	Chordata	Chordata	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to steroid hormone [GO:0048545]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	apical part of cell [GO:0045177]; axon [GO:0030424]; basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microvillus [GO:0005902]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d3v4ba1_d4hclb1__1			Proteobacteria	Proteobacteria	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]				magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3v4ec__d3bsyb___1			Firmicutes	Proteobacteria	acetyltransferase activity [GO:0016407]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; protein N-linked glycosylation via asparagine [GO:0018279]		protein N-linked glycosylation via asparagine [GO:0018279]			acetyltransferase activity [GO:0016407]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d3v4kb__d3oj6c___1	Metazoa	Fungi	Chordata	Ascomycota	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	base conversion or substitution editing [GO:0016553]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; negative regulation of viral process [GO:0048525]; positive regulation of defense response to virus by host [GO:0002230]; viral process [GO:0016032]	response to antibiotic [GO:0046677]	apolipoprotein B mRNA editing enzyme complex [GO:0030895]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; P-body [GO:0000932]; ribonucleoprotein complex [GO:1990904]		cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d3v4na2_d1m1oa2__1			Firmicutes	Proteobacteria	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	isoprenoid biosynthetic process [GO:0008299]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3v4pl2_d5nmdd2__1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]		cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; cell migration [GO:0016477]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]	
d3v4pn2_d1yn7a1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; cell migration [GO:0016477]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3v4vl1_d1rzic2__1	Metazoa		Chordata		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]		cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; cell migration [GO:0016477]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]	
d3v4vl2_d2r56m2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; cell migration [GO:0016477]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3v4vl2_d4n0fe2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell migration [GO:0016477]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell-matrix adhesion involved in ameboidal cell migration [GO:0003366]; cell migration [GO:0016477]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte tethering or rolling [GO:0050901]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell migration [GO:0072678]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alpha4-beta7 complex [GO:0034669]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell adhesion molecule binding [GO:0050839]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; signaling receptor activity [GO:0038023]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3v4xb1_d1teeb2__1			Firmicutes	Actinobacteria	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]	isoprenoid biosynthetic process [GO:0008299]	chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]			hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d3v4xb1_d2wgfa1__1			Firmicutes	Actinobacteria	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]	isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; fatty acid elongation, saturated fatty acid [GO:0019367]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; identical protein binding [GO:0042802]
d3v4xc1_d3awjb2__1		Viridiplantae	Firmicutes	Streptophyta	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	isoprenoid biosynthetic process [GO:0008299]	biosynthetic process [GO:0009058]			hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d3v4xc2_d5w8qb1__1		Viridiplantae	Firmicutes	Streptophyta	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	biphenyl synthase activity [GO:0033815]; biosynthetic process [GO:0009058]	isoprenoid biosynthetic process [GO:0008299]	biosynthetic process [GO:0009058]			hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	biphenyl synthase activity [GO:0033815]
d3v4xd1_d1xesa2__1		Viridiplantae	Firmicutes	Streptophyta	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]	isoprenoid biosynthetic process [GO:0008299]	biosynthetic process [GO:0009058]		cytoplasm [GO:0005737]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	pinosylvin synthase activity [GO:0050198]
d3v4xd2_d2vu2b2__1			Firmicutes	Proteobacteria	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	isoprenoid biosynthetic process [GO:0008299]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3v4ya__d5osij___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; retromer complex [GO:0030904]; retromer, cargo-selective complex [GO:0030906]; metal ion binding [GO:0046872]; endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	cytosol [GO:0005829]; early endosome [GO:0005769]; endosome [GO:0005768]; endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; retromer, cargo-selective complex [GO:0030906]; retromer complex [GO:0030904]	cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]	metal ion binding [GO:0046872]
d3v4ye__d1oidb2__1	Metazoa		Chordata	Proteobacteria	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]	beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	nucleotide catabolic process [GO:0009166]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	outer membrane-bounded periplasmic space [GO:0030288]	cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]
d3v4yg1_d1hpub2__1	Metazoa		Chordata	Proteobacteria	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	outer membrane-bounded periplasmic space [GO:0030288]; 5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]; nucleotide catabolic process [GO:0009166]	beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	nucleotide catabolic process [GO:0009166]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	outer membrane-bounded periplasmic space [GO:0030288]	cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]	5'-nucleotidase activity [GO:0008253]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; UDP-sugar diphosphatase activity [GO:0008768]
d3v4za1_d1eyza2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytosol [GO:0005829]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]; 'de novo' IMP biosynthetic process [GO:0006189]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]	cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; phosphoribosylglycinamide formyltransferase 2 activity [GO:0043815]; phosphoribosylglycinamide formyltransferase activity [GO:0004644]
d3v4zb1_d1t36e4__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]	cytosol [GO:0005829]	carbamoyl-phosphate synthase complex [GO:0005951]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [GO:0004088]
d3v56e__d1tnfb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]; B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell costimulation [GO:0031296]; B cell homeostasis [GO:0001782]; immune response [GO:0006955]; immunoglobulin secretion [GO:0048305]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of germinal center formation [GO:0002636]; positive regulation of T cell proliferation [GO:0042102]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	cytokine activity [GO:0005125]; signaling receptor binding [GO:0005102]; tumor necrosis factor receptor binding [GO:0005164]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d3v60a__d2nbwb___1	Fungi	Fungi	Ascomycota	Ascomycota	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleotide-excision repair factor 2 complex [GO:0000111]; proteasome complex [GO:0000502]; damaged DNA binding [GO:0003684]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deglycosylation [GO:0006517]; ubiquitin-dependent ERAD pathway [GO:0030433]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deglycosylation [GO:0006517]; ubiquitin-dependent ERAD pathway [GO:0030433]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleotide-excision repair factor 2 complex [GO:0000111]; proteasome complex [GO:0000502]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	damaged DNA binding [GO:0003684]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; protein binding, bridging [GO:0030674]; ubiquitin binding [GO:0043130]
d3v61a__d1gc6a3__1	Fungi	Metazoa	Ascomycota	Chordata	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d3v61b1_d5ixab1__1	Fungi		Ascomycota		chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	host cell nucleus [GO:0042025]; virion [GO:0019012]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	host cell nucleus [GO:0042025]; virion [GO:0019012]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]
d3v62b2_d1mmia1__1	Fungi		Ascomycota	Proteobacteria	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; error-free translesion synthesis [GO:0070987]; establishment of mitotic sister chromatid cohesion [GO:0034087]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; maintenance of DNA trinucleotide repeats [GO:0035753]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid cohesion [GO:0007064]; nucleotide-excision repair [GO:0006289]; positive regulation of exodeoxyribonuclease activity [GO:1902394]; positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [GO:1903022]; postreplication repair [GO:0006301]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	chromosome, telomeric region [GO:0000781]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; replication fork [GO:0005657]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; identical protein binding [GO:0042802]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3v64a1_d3sisb___1	Metazoa		Chordata		cell surface [GO:0009986]; dendrite [GO:0030425]; integral component of membrane [GO:0016021]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]; apolipoprotein binding [GO:0034185]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; receptor tyrosine kinase binding [GO:0030971]; scaffold protein binding [GO:0097110]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055]	permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; dendrite [GO:0030425]; integral component of membrane [GO:0016021]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; postsynaptic density [GO:0014069]; synaptic membrane [GO:0097060]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell plasma membrane [GO:0020002]; host cell rough endoplasmic reticulum [GO:0044168]; host cytoskeleton [GO:0044163]; membrane [GO:0016020]; viral outer capsid [GO:0039624]	apolipoprotein binding [GO:0034185]; calcium ion binding [GO:0005509]; protein homodimerization activity [GO:0042803]; receptor tyrosine kinase binding [GO:0030971]; scaffold protein binding [GO:0097110]	
d3v6cb1_d4kslt2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d3v6fb2_d1zhbg1__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3v6ff1_d2ipka1__1		Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d3v6ff1_d5iw1d2__1												
d3v6ff2_d5w1wq1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3v6fl1_d5lmjc1__1												
d3v6fl2_d2ckbc2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		antigen processing and presentation of endogenous peptide antigen via MHC class Ib [GO:0002476]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; inner ear development [GO:0048839]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]		external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		beta-2-microglobulin binding [GO:0030881]; peptide antigen binding [GO:0042605]; peptide binding [GO:0042277]; protein heterodimerization activity [GO:0046982]; TAP binding [GO:0046977]
d3v6fl2_d3zknd1__1		Metazoa		Chordata		dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]		aspartic-type endopeptidase activity [GO:0004190]
d3v6oe1_d5ukrl2__1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; leptin receptor activity [GO:0038021]; peptide hormone binding [GO:0017046]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; bone growth [GO:0098868]; cell surface receptor signaling pathway [GO:0007166]; cholesterol metabolic process [GO:0008203]; energy homeostasis [GO:0097009]; energy reserve metabolic process [GO:0006112]; glial cell proliferation [GO:0014009]; glucose homeostasis [GO:0042593]; glycogen metabolic process [GO:0005977]; leptin-mediated signaling pathway [GO:0033210]; multicellular organism development [GO:0007275]; negative regulation of autophagy [GO:0010507]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of hydrolase activity [GO:0051346]; phagocytosis [GO:0006909]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of bone remodeling [GO:0046850]; regulation of feeding behavior [GO:0060259]; response to leptin [GO:0044321]; sexual reproduction [GO:0019953]; T cell differentiation [GO:0030217]		angiogenesis [GO:0001525]; bone growth [GO:0098868]; cell surface receptor signaling pathway [GO:0007166]; cholesterol metabolic process [GO:0008203]; energy homeostasis [GO:0097009]; energy reserve metabolic process [GO:0006112]; glial cell proliferation [GO:0014009]; glucose homeostasis [GO:0042593]; glycogen metabolic process [GO:0005977]; leptin-mediated signaling pathway [GO:0033210]; multicellular organism development [GO:0007275]; negative regulation of autophagy [GO:0010507]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of hydrolase activity [GO:0051346]; phagocytosis [GO:0006909]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of bone remodeling [GO:0046850]; regulation of feeding behavior [GO:0060259]; response to leptin [GO:0044321]; sexual reproduction [GO:0019953]; T cell differentiation [GO:0030217]		basolateral plasma membrane [GO:0016323]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; receptor complex [GO:0043235]		cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; leptin receptor activity [GO:0038021]; peptide hormone binding [GO:0017046]; transmembrane signaling receptor activity [GO:0004888]	
d3v6oe2_d5iueh___1	Metazoa	Metazoa	Chordata	Chordata	basolateral plasma membrane [GO:0016323]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; leptin receptor activity [GO:0038021]; peptide hormone binding [GO:0017046]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; bone growth [GO:0098868]; cell surface receptor signaling pathway [GO:0007166]; cholesterol metabolic process [GO:0008203]; energy homeostasis [GO:0097009]; energy reserve metabolic process [GO:0006112]; glial cell proliferation [GO:0014009]; glucose homeostasis [GO:0042593]; glycogen metabolic process [GO:0005977]; leptin-mediated signaling pathway [GO:0033210]; multicellular organism development [GO:0007275]; negative regulation of autophagy [GO:0010507]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of hydrolase activity [GO:0051346]; phagocytosis [GO:0006909]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of bone remodeling [GO:0046850]; regulation of feeding behavior [GO:0060259]; response to leptin [GO:0044321]; sexual reproduction [GO:0019953]; T cell differentiation [GO:0030217]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	angiogenesis [GO:0001525]; bone growth [GO:0098868]; cell surface receptor signaling pathway [GO:0007166]; cholesterol metabolic process [GO:0008203]; energy homeostasis [GO:0097009]; energy reserve metabolic process [GO:0006112]; glial cell proliferation [GO:0014009]; glucose homeostasis [GO:0042593]; glycogen metabolic process [GO:0005977]; leptin-mediated signaling pathway [GO:0033210]; multicellular organism development [GO:0007275]; negative regulation of autophagy [GO:0010507]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of hydrolase activity [GO:0051346]; phagocytosis [GO:0006909]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of bone remodeling [GO:0046850]; regulation of feeding behavior [GO:0060259]; response to leptin [GO:0044321]; sexual reproduction [GO:0019953]; T cell differentiation [GO:0030217]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	basolateral plasma membrane [GO:0016323]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; receptor complex [GO:0043235]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; leptin receptor activity [GO:0038021]; peptide hormone binding [GO:0017046]; transmembrane signaling receptor activity [GO:0004888]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3v6of2_d4fnll1__1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; leptin receptor activity [GO:0038021]; peptide hormone binding [GO:0017046]; transmembrane signaling receptor activity [GO:0004888]; angiogenesis [GO:0001525]; bone growth [GO:0098868]; cell surface receptor signaling pathway [GO:0007166]; cholesterol metabolic process [GO:0008203]; energy homeostasis [GO:0097009]; energy reserve metabolic process [GO:0006112]; glial cell proliferation [GO:0014009]; glucose homeostasis [GO:0042593]; glycogen metabolic process [GO:0005977]; leptin-mediated signaling pathway [GO:0033210]; multicellular organism development [GO:0007275]; negative regulation of autophagy [GO:0010507]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of hydrolase activity [GO:0051346]; phagocytosis [GO:0006909]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of bone remodeling [GO:0046850]; regulation of feeding behavior [GO:0060259]; response to leptin [GO:0044321]; sexual reproduction [GO:0019953]; T cell differentiation [GO:0030217]		angiogenesis [GO:0001525]; bone growth [GO:0098868]; cell surface receptor signaling pathway [GO:0007166]; cholesterol metabolic process [GO:0008203]; energy homeostasis [GO:0097009]; energy reserve metabolic process [GO:0006112]; glial cell proliferation [GO:0014009]; glucose homeostasis [GO:0042593]; glycogen metabolic process [GO:0005977]; leptin-mediated signaling pathway [GO:0033210]; multicellular organism development [GO:0007275]; negative regulation of autophagy [GO:0010507]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of hydrolase activity [GO:0051346]; phagocytosis [GO:0006909]; positive regulation of cold-induced thermogenesis [GO:0120162]; regulation of bone remodeling [GO:0046850]; regulation of feeding behavior [GO:0060259]; response to leptin [GO:0044321]; sexual reproduction [GO:0019953]; T cell differentiation [GO:0030217]		basolateral plasma membrane [GO:0016323]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; receptor complex [GO:0043235]		cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; identical protein binding [GO:0042802]; leptin receptor activity [GO:0038021]; peptide hormone binding [GO:0017046]; transmembrane signaling receptor activity [GO:0004888]	
d3v6ta__d4osha___1				Proteobacteria								
d3v7ja1_d9icha1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d3v7ka3_d1bpza4__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d3v7ka3_d1r89a2__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	ATP binding [GO:0005524]; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]; RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	RNA repair [GO:0042245]; tRNA 3'-terminal CCA addition [GO:0001680]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]		damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity [GO:0052929]; ATP binding [GO:0005524]; CTP:3'-cytidine-tRNA cytidylyltransferase activity [GO:0052928]; CTP:tRNA cytidylyltransferase activity [GO:0052927]; magnesium ion binding [GO:0000287]; tRNA binding [GO:0000049]; tRNA cytidylyltransferase activity [GO:0016437]
d3v7la3_d4nxza3__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-dependent DNA replication [GO:0006261]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; in utero embryonic development [GO:0001701]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; protein deubiquitination [GO:0016579]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; spindle microtubule [GO:0005876]	damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]	damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA-directed DNA polymerase activity [GO:0003887]; enzyme binding [GO:0019899]; lyase activity [GO:0016829]; metal ion binding [GO:0046872]; microtubule binding [GO:0008017]
d3v7ma1_d4f33c2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3v8oa1_d1vkxa1__1	Metazoa	Metazoa	Chordata	Chordata	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3v8ob1_d4x42b1__1	Metazoa		Chordata		costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d3v8ob2_d2bp3b___1	Metazoa	Metazoa	Chordata	Chordata	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]; actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; thrombin-activated receptor activity [GO:0015057]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell surface receptor signaling pathway [GO:0007166]; fibrinolysis [GO:0042730]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; regulation of blood coagulation [GO:0030193]; regulation of megakaryocyte differentiation [GO:0045652]	costamere [GO:0043034]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; sarcoplasm [GO:0016528]; Z disc [GO:0030018]	anchored component of external side of plasma membrane [GO:0031362]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	actin binding [GO:0003779]; ankyrin binding [GO:0030506]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]	thrombin-activated receptor activity [GO:0015057]
d3v93b__d5tzac___1		Metazoa		Chordata	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	signal transduction [GO:0007165]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d3v93c__d1oynd___1		Metazoa		Chordata	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]		apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d3v93g__d4c1id___1		Metazoa		Chordata	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	signal transduction [GO:0007165]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d3v94a__d3k3ea___1		Metazoa		Chordata	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	signal transduction [GO:0007165]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3v94b__d1mkdb___1		Metazoa		Chordata	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]		apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d3v94b__d4tpmb___1		Metazoa		Chordata	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]		cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3v94c__d3sl5a___1		Metazoa		Chordata	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	signal transduction [GO:0007165]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]		apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d3v94d__d3gwta___1		Metazoa		Chordata	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]	signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cellular response to drug [GO:0035690]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; neutrophil homeostasis [GO:0001780]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of high voltage-gated calcium channel activity [GO:1901841]; T cell receptor signaling pathway [GO:0050852]		centrosome [GO:0005813]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; excitatory synapse [GO:0060076]; gamma-tubulin complex [GO:0000930]; postsynaptic density [GO:0014069]; synaptic vesicle [GO:0008021]; voltage-gated calcium channel complex [GO:0005891]; Z disc [GO:0030018]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; cAMP binding [GO:0030552]; gamma-tubulin binding [GO:0043015]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]
d3v94g__d3qi3b___1		Metazoa		Chordata	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	signal transduction [GO:0007165]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3v95a1_d5fhbl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3v95a2_d1hzhh1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3v95b2_d4k7pl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3v9bb__d4c1ia___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d3v9bd__d4ajma1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3v9ca2_d2qt6b1__1	Fungi	Fungi	Basidiomycota	Basidiomycota	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]					copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d3v9ca3_d1ndta2__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]			copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3v9gd__d1o00e___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; 4-hydroxyproline catabolic process [GO:0019470]; glyoxylate metabolic process [GO:0046487]; proline catabolic process [GO:0006562]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	4-hydroxyproline catabolic process [GO:0019470]; glyoxylate metabolic process [GO:0046487]; proline catabolic process [GO:0006562]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	mitochondrial matrix [GO:0005759]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3v9ja1_d4i3xe___1	Metazoa		Chordata	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; identical protein binding [GO:0042802]; proline catabolic process to glutamate [GO:0010133]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	proline catabolic process to glutamate [GO:0010133]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3v9la__d2onmc___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; identical protein binding [GO:0042802]; proline catabolic process to glutamate [GO:0010133]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	proline catabolic process to glutamate [GO:0010133]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; identical protein binding [GO:0042802]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3v9lb1_d4gnzc___1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; identical protein binding [GO:0042802]; proline catabolic process to glutamate [GO:0010133]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]; 10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	proline catabolic process to glutamate [GO:0010133]	10-formyltetrahydrofolate catabolic process [GO:0009258]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]; protein-containing complex [GO:0032991]	1-pyrroline-5-carboxylate dehydrogenase activity [GO:0003842]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; identical protein binding [GO:0042802]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase (NADP+) activity [GO:0033721]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; formyltetrahydrofolate dehydrogenase activity [GO:0016155]; hydroxymethyl-, formyl- and related transferase activity [GO:0016742]; protein-containing complex binding [GO:0044877]
d3va2a__d5d72a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]; cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	cytokine-mediated signaling pathway [GO:0019221]; inflammatory response to antigenic stimulus [GO:0002437]; MAPK cascade [GO:0000165]; positive regulation of leukocyte proliferation [GO:0070665]; regulation of interleukin-5 production [GO:0032674]; signal transduction [GO:0007165]	cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; dendritic cell differentiation [GO:0097028]; embryonic placenta development [GO:0001892]; epithelial fluid transport [GO:0042045]; histamine secretion [GO:0001821]; immune response [GO:0006955]; macrophage activation [GO:0042116]; macrophage differentiation [GO:0030225]; MAPK cascade [GO:0000165]; monocyte differentiation [GO:0030224]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cytolysis [GO:0045918]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil differentiation [GO:0030223]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of podosome assembly [GO:0071803]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of myeloid cell differentiation [GO:0045637]; response to fluid shear stress [GO:0034405]; response to silicon dioxide [GO:0034021]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]	cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-5 receptor activity [GO:0004914]	cytokine activity [GO:0005125]; granulocyte macrophage colony-stimulating factor receptor binding [GO:0005129]; growth factor activity [GO:0008083]
d3va8a2_d1ecqc1__1				Proteobacteria		glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]		D-glucarate catabolic process [GO:0042838]				glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3va8a2_d3i6eg2__1				Proteobacteria		chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]; aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]		aromatic compound catabolic process [GO:0019439]; cellular amino acid catabolic process [GO:0009063]				chloromuconate cycloisomerase activity [GO:0018850]; manganese ion binding [GO:0030145]; muconate cycloisomerase activity [GO:0018849]
d3vaxa__d4b9bb___1			Actinobacteria	Proteobacteria	catalytic activity [GO:0003824]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]; beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]		beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]			catalytic activity [GO:0003824]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]
d3vaxb__d5ft4b___1			Actinobacteria	Proteobacteria	catalytic activity [GO:0003824]	cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]; selenocysteine lyase activity [GO:0009000]; sulfurtransferase activity [GO:0016783]; iron-sulfur cluster assembly [GO:0016226]; sulfur amino acid metabolic process [GO:0000096]		iron-sulfur cluster assembly [GO:0016226]; sulfur amino acid metabolic process [GO:0000096]			catalytic activity [GO:0003824]	cysteine desulfurase activity [GO:0031071]; pyridoxal phosphate binding [GO:0030170]; selenocysteine lyase activity [GO:0009000]; sulfurtransferase activity [GO:0016783]
d3vayb__d4hgrf___1			Proteobacteria	Bacteroidetes	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]		lipopolysaccharide biosynthetic process [GO:0009103]			hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d3vbaa1_d1v7la___1			Euryarchaeota	Euryarchaeota	(R)-2-methylmalate dehydratase activity [GO:0047508]; 3-isopropylmalate dehydratase activity [GO:0003861]; maleate hydratase activity [GO:0050075]; isoleucine biosynthetic process [GO:0009097]; leucine biosynthetic process [GO:0009098]	3-isopropylmalate dehydratase activity [GO:0003861]; leucine biosynthetic process [GO:0009098]	isoleucine biosynthetic process [GO:0009097]; leucine biosynthetic process [GO:0009098]	leucine biosynthetic process [GO:0009098]			(R)-2-methylmalate dehydratase activity [GO:0047508]; 3-isopropylmalate dehydratase activity [GO:0003861]; maleate hydratase activity [GO:0050075]	3-isopropylmalate dehydratase activity [GO:0003861]
d3vbad__d2b3yb1__1		Metazoa	Euryarchaeota	Chordata	(R)-2-methylmalate dehydratase activity [GO:0047508]; 3-isopropylmalate dehydratase activity [GO:0003861]; maleate hydratase activity [GO:0050075]; isoleucine biosynthetic process [GO:0009097]; leucine biosynthetic process [GO:0009098]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; intestinal absorption [GO:0050892]; post-embryonic development [GO:0009791]; regulation of translation [GO:0006417]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099]	isoleucine biosynthetic process [GO:0009097]; leucine biosynthetic process [GO:0009098]	cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; intestinal absorption [GO:0050892]; post-embryonic development [GO:0009791]; regulation of translation [GO:0006417]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]	(R)-2-methylmalate dehydratase activity [GO:0047508]; 3-isopropylmalate dehydratase activity [GO:0003861]; maleate hydratase activity [GO:0050075]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3vbae__d2b3xa1__1		Metazoa	Euryarchaeota	Chordata	(R)-2-methylmalate dehydratase activity [GO:0047508]; 3-isopropylmalate dehydratase activity [GO:0003861]; maleate hydratase activity [GO:0050075]; isoleucine biosynthetic process [GO:0009097]; leucine biosynthetic process [GO:0009098]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; intestinal absorption [GO:0050892]; post-embryonic development [GO:0009791]; regulation of translation [GO:0006417]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099]	isoleucine biosynthetic process [GO:0009097]; leucine biosynthetic process [GO:0009098]	cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; intestinal absorption [GO:0050892]; post-embryonic development [GO:0009791]; regulation of translation [GO:0006417]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; mitochondrion [GO:0005739]	(R)-2-methylmalate dehydratase activity [GO:0047508]; 3-isopropylmalate dehydratase activity [GO:0003861]; maleate hydratase activity [GO:0050075]	3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; iron-responsive element binding [GO:0030350]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3vbaf__d1b0ja1__1		Metazoa	Euryarchaeota	Chordata	(R)-2-methylmalate dehydratase activity [GO:0047508]; 3-isopropylmalate dehydratase activity [GO:0003861]; maleate hydratase activity [GO:0050075]; isoleucine biosynthetic process [GO:0009097]; leucine biosynthetic process [GO:0009098]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; 4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; metal ion binding [GO:0046872]; tricarboxylic acid cycle [GO:0006099]	isoleucine biosynthetic process [GO:0009097]; leucine biosynthetic process [GO:0009098]	tricarboxylic acid cycle [GO:0006099]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	(R)-2-methylmalate dehydratase activity [GO:0047508]; 3-isopropylmalate dehydratase activity [GO:0003861]; maleate hydratase activity [GO:0050075]	4 iron, 4 sulfur cluster binding [GO:0051539]; aconitate hydratase activity [GO:0003994]; metal ion binding [GO:0046872]
d3vbeb__d3vsdb___1	Viridiplantae		Streptophyta	Crenarchaeota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]; cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]; cysteine biosynthetic process from serine [GO:0006535]	cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]		cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]	cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]
d3vbed__d3vc3c___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]; cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]; cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]	cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]
d3vbfa__d1al21___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3vbfb__d2ws93___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	icosahedral viral capsid [GO:0019030]; structural molecule activity [GO:0005198]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	icosahedral viral capsid [GO:0019030]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d3vbga__d3jzqa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; 5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]
d3vbha__d1qjzb___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; structural molecule activity [GO:0005198]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	structural molecule activity [GO:0005198]
d3vbob__d1x36a___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d3vbsa__d1opoa___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	T=3 icosahedral viral capsid [GO:0039617]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	T=3 icosahedral viral capsid [GO:0039617]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d3vbsc__d4y5zg___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d3vc3d__d1cw2b___1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]; cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]; tryptophan biosynthetic process [GO:0000162]	cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	tryptophan biosynthetic process [GO:0000162]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; tryptophan synthase activity [GO:0004834]
d3vc6a1_d1sjac2__1			Actinobacteria	Actinobacteria	metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]		menaquinone biosynthetic process [GO:0009234]			metal ion binding [GO:0046872]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3vcnc1_d1sjab2__1			Proteobacteria	Actinobacteria	magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]; carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	carbohydrate catabolic process [GO:0016052]; cellular amino acid catabolic process [GO:0009063]	menaquinone biosynthetic process [GO:0009234]			magnesium ion binding [GO:0000287]; mannonate dehydratase activity [GO:0008927]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]
d3vcoa1_d4kl9a1__1	Metazoa		Platyhelminthes	Actinobacteria	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; NADP+ binding [GO:0070401]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	glycine biosynthetic process [GO:0006545]; tetrahydrofolate biosynthetic process [GO:0046654]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	dihydrofolate reductase activity [GO:0004146]; NADP+ binding [GO:0070401]; NADP binding [GO:0050661]
d3vcza__d1nq3a___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	mitochondrial matrix [GO:0005759]; nucleus [GO:0005634]; peroxisome [GO:0005777]; deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; mRNA binding [GO:0003729]; mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]		mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; negative regulation of translation [GO:0017148]; organonitrogen compound catabolic process [GO:1901565]		mitochondrial matrix [GO:0005759]; nucleus [GO:0005634]; peroxisome [GO:0005777]	metal ion binding [GO:0046872]	deaminase activity [GO:0019239]; endoribonuclease activity, producing 3'-phosphomonoesters [GO:0016892]; mRNA binding [GO:0003729]
d3vd0a1_d1tsrc___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d3vd0b1_d1eana___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3vd0k1_d1hjbf___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3vd0l1_d1xbrb___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II activating transcription factor binding [GO:0001102]; cellular response to fibroblast growth factor stimulus [GO:0044344]; determination of left/right symmetry [GO:0007368]; embryonic axis specification [GO:0000578]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cellular response to fibroblast growth factor stimulus [GO:0044344]; determination of left/right symmetry [GO:0007368]; embryonic axis specification [GO:0000578]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleus [GO:0005634]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; RNA polymerase II activating transcription factor binding [GO:0001102]
d3vd1b1_d4kvpb___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d3vd1c1_d2as5m2__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	nuclear chromatin [GO:0000790]; androgen receptor binding [GO:0050681]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; camera-type eye development [GO:0043010]; caudate nucleus development [GO:0021757]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; innate vocalization behavior [GO:0098582]; lung alveolus development [GO:0048286]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of mesenchymal cell proliferation [GO:0002053]; post-embryonic development [GO:0009791]; putamen development [GO:0021758]; response to testosterone [GO:0033574]; righting reflex [GO:0060013]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; vocal learning [GO:0042297]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	camera-type eye development [GO:0043010]; caudate nucleus development [GO:0021757]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; innate vocalization behavior [GO:0098582]; lung alveolus development [GO:0048286]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of mesenchymal cell proliferation [GO:0002053]; post-embryonic development [GO:0009791]; putamen development [GO:0021758]; response to testosterone [GO:0033574]; righting reflex [GO:0060013]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; vocal learning [GO:0042297]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nuclear chromatin [GO:0000790]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	androgen receptor binding [GO:0050681]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]
d3vd1c1_d4agnb___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d3vd1i1_d1p7ho2__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3vd1i1_d2h1lp2__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d3vd1l1_d1e50q___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; chondrocyte differentiation [GO:0002062]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; peripheral nervous system neuron development [GO:0048935]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytokine-mediated signaling pathway [GO:0001959]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of keratinocyte differentiation [GO:0045616]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of myeloid cell differentiation [GO:0045637]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of Wnt signaling pathway [GO:0030111]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	chondrocyte differentiation [GO:0002062]; hematopoietic stem cell proliferation [GO:0071425]; hemopoiesis [GO:0030097]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron differentiation [GO:0030182]; peripheral nervous system neuron development [GO:0048935]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cytokine-mediated signaling pathway [GO:0001959]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of keratinocyte differentiation [GO:0045616]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of myeloid cell differentiation [GO:0045637]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of Wnt signaling pathway [GO:0030111]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3vd1l1_d2qxac___1	Metazoa		Chordata		cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]		activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]		cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	
d3vd3a4_d2vqub2__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-mannosidase activity [GO:0004567]
d3vd3b5_d4duxb5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd3c1_d4xzug___1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	lactose catabolic process [GO:0005990]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	beta-galactosidase complex [GO:0009341]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]
d3vd3c5_d2f2hc2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d3vd3d2_d2vqta3__1			Proteobacteria	Bacteroidetes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-mannosidase activity [GO:0004567]; carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-mannosidase activity [GO:0004567]
d3vd3d3_d1gqkb1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]; alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]; glucuronoxylan catabolic process [GO:2000886]	lactose catabolic process [GO:0005990]	glucuronoxylan catabolic process [GO:2000886]	beta-galactosidase complex [GO:0009341]	cell outer membrane [GO:0009279]; extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-glucuronidase activity [GO:0046559]; xylan alpha-1,2-glucuronosidase activity [GO:0033939]
d3vd4a1_d1ot5a1__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]	lactose catabolic process [GO:0005990]	peptide pheromone maturation [GO:0007323]; protein processing [GO:0016485]	beta-galactosidase complex [GO:0009341]	fungal-type vacuole [GO:0000324]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; trans-Golgi network [GO:0005802]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d3vd4a2_d1hn1c2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd4a2_d3t2pc4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd4a5_d3t2qc5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd4b2_d3t2pb4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd4b5_d3lppb1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	beta-galactosidase complex [GO:0009341]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]
d3vd4c4_d3t2oc2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd4d1_d4omcb2__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	lactose catabolic process [GO:0005990]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cornification [GO:0070268]; dibasic protein processing [GO:0090472]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of transforming growth factor beta1 activation [GO:1901394]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of lipoprotein lipase activity [GO:0051004]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral life cycle [GO:0019058]; viral protein processing [GO:0019082]; zymogen activation [GO:0031638]; zymogen inhibition [GO:0097341]	beta-galactosidase complex [GO:0009341]	cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of Golgi membrane [GO:0030173]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; trans-Golgi network transport vesicle [GO:0030140]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; nerve growth factor binding [GO:0048406]; peptidase activity [GO:0008233]; peptide binding [GO:0042277]; protease binding [GO:0002020]; serine-type endopeptidase activity [GO:0004252]; serine-type endopeptidase inhibitor activity [GO:0004867]
d3vd4d3_d2dqxa___1		Viridiplantae	Proteobacteria	Streptophyta	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d3vd5a5_d3t2oa5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd5b3_d4ha4a___1			Proteobacteria	Crenarchaeota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase activity [GO:0004565]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-galactosidase activity [GO:0004565]; metal ion binding [GO:0046872]
d3vd5b4_d1hn1c1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd5c5_d2brwa3__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	cell wall [GO:0005618]; extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; hyaluronate lyase activity [GO:0030340]
d3vd5d1_d1w9tb___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group [GO:0052861]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group [GO:0052861]
d3vd5d5_d1tqsa2__1		Metazoa	Proteobacteria	Arthropoda	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]; alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]; encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	lactose catabolic process [GO:0005990]	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein glycosylation [GO:0006486]; rhodopsin biosynthetic process [GO:0016063]	beta-galactosidase complex [GO:0009341]	endoplasmic reticulum [GO:0005783]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of membrane [GO:0016021]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-mannosidase activity [GO:0004559]; carbohydrate binding [GO:0030246]; mannosidase activity [GO:0015923]; mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]; metal ion binding [GO:0046872]
d3vd7a2_d3muy24__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd7a2_d3vdab4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd7a3_d1cxia4__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3vd7a4_d3t0dc2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd7a5_d1l7jb___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose metabolic process [GO:0006012]	lactose catabolic process [GO:0005990]	galactose metabolic process [GO:0006012]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d3vd7b1_d4qx1a3__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	lactose catabolic process [GO:0005990]	sporulation resulting in formation of a cellular spore [GO:0030435]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d3vd7b2_d4jkma2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	lactose catabolic process [GO:0005990]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	beta-galactosidase complex [GO:0009341]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3vd7b3_d1ukpa___1		Viridiplantae	Proteobacteria	Streptophyta	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]
d3vd7c1_d3cqoa1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	metal ion binding [GO:0046872]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]
d3vd7c2_d3t09d4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd7c3_d1f49g5__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3vd7c3_d3vgea2__1			Proteobacteria	Crenarchaeota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	lactose catabolic process [GO:0005990]	trehalose biosynthetic process [GO:0005992]	beta-galactosidase complex [GO:0009341]	cytoplasm [GO:0005737]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]
d3vd7c4_d3sepb2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd7d3_d1j10a2__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3vd7d5_d4duvc5__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd9a3_d1ghop5__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3vd9a5_d1so0c1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	lactose catabolic process [GO:0005990]	galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	beta-galactosidase complex [GO:0009341]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]
d3vd9c4_d1jyzp1__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3vd9d1_d3njxa3__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	lactose catabolic process [GO:0005990]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; rhamnogalacturonan endolyase activity [GO:0102210]
d3vd9d4_d3dypb2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vd9d4_d3vdab2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vdaa3_d1bgad___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	lactose catabolic process [GO:0005990]	cellulose catabolic process [GO:0030245]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3vdab3_d4qlja___1		Viridiplantae	Proteobacteria	Streptophyta	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d3vdab5_d1yq2c4__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3vdac1_d1w8ta___1		Fungi	Proteobacteria	Chytridiomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3vdac3_d2c8nb2__1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]; alpha-L-arabinofuranosidase activity [GO:0046556]; arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	lactose catabolic process [GO:0005990]	arabinan catabolic process [GO:0031222]; L-arabinose metabolic process [GO:0046373]	beta-galactosidase complex [GO:0009341]	cytoplasm [GO:0005737]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-L-arabinofuranosidase activity [GO:0046556]
d3vdac5_d1xsic2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-D-xyloside xylohydrolase [GO:0061634]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; xyloglucan 1,6-alpha-xylosidase activity [GO:0080176]
d3vdba5_d1z45a1__1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytosol [GO:0005829]; aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; UDP-glucose 4-epimerase activity [GO:0003978]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]	lactose catabolic process [GO:0005990]	galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]	beta-galactosidase complex [GO:0009341]	cytosol [GO:0005829]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	aldose 1-epimerase activity [GO:0004034]; carbohydrate binding [GO:0030246]; UDP-glucose 4-epimerase activity [GO:0003978]
d3vdbb2_d3iapa4__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vdbb3_d3wq4b___1		Viridiplantae	Proteobacteria	Streptophyta	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102402]; beta-primeverosidase activity [GO:0050535]; linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102404]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102402]; beta-primeverosidase activity [GO:0050535]; linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102404]
d3vdbc1_d3k46b1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cytosol [GO:0005829]; beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	lactose catabolic process [GO:0005990]	glucuronoside catabolic process [GO:0019391]; protein homotetramerization [GO:0051289]	beta-galactosidase complex [GO:0009341]	cytosol [GO:0005829]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	beta-glucuronidase activity [GO:0004566]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]
d3vdbc3_d3n9ka___1		Fungi	Proteobacteria	Ascomycota	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]; cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	lactose catabolic process [GO:0005990]	cell-substrate adhesion [GO:0031589]; cellular glucan metabolic process [GO:0006073]; fungal-type cell wall organization [GO:0031505]; pathogenesis [GO:0009405]; single-species biofilm formation in or on host organism [GO:0044407]; single-species biofilm formation on inanimate substrate [GO:0044011]	beta-galactosidase complex [GO:0009341]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	cell adhesion molecule binding [GO:0050839]; glucan exo-1,3-beta-glucosidase activity [GO:0004338]; transferase activity [GO:0016740]
d3vdbc5_d3l4ya1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]; neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	lactose catabolic process [GO:0005990]	neutrophil degranulation [GO:0043312]; polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	beta-galactosidase complex [GO:0009341]	apical plasma membrane [GO:0016324]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	amylase activity [GO:0016160]; carbohydrate binding [GO:0030246]; catalytic activity [GO:0003824]; glucan 1,4-alpha-glucosidase activity [GO:0004339]; maltose alpha-glucosidase activity [GO:0032450]
d3vdbd1_d1kexa___1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]; coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-cell signaling [GO:0007267]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal ganglion cell axon guidance [GO:0031290]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	lactose catabolic process [GO:0005990]	actin cytoskeleton reorganization [GO:0031532]; angiogenesis [GO:0001525]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; animal organ morphogenesis [GO:0009887]; artery morphogenesis [GO:0048844]; axonal fasciculation [GO:0007413]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; basal dendrite arborization [GO:0150020]; basal dendrite development [GO:0150018]; branching involved in blood vessel morphogenesis [GO:0001569]; branchiomotor neuron axon guidance [GO:0021785]; cell-cell signaling [GO:0007267]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; commissural neuron axon guidance [GO:0071679]; coronary artery morphogenesis [GO:0060982]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; dorsal root ganglion morphogenesis [GO:1904835]; endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; endothelial tip cell fate specification [GO:0097102]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; integrin-mediated signaling pathway [GO:0007229]; motor neuron migration [GO:0097475]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; neuron migration [GO:0001764]; neuropilin signaling pathway [GO:0038189]; otic placode development [GO:1905040]; outflow tract septum morphogenesis [GO:0003148]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive chemotaxis [GO:0050918]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytokine activity [GO:0060301]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of retinal ganglion cell axon guidance [GO:1902336]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynapse organization [GO:0099173]; protein localization to early endosome [GO:1902946]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of retinal ganglion cell axon guidance [GO:0090259]; regulation of vesicle-mediated transport [GO:0060627]; renal artery morphogenesis [GO:0061441]; response to wounding [GO:0009611]; retinal ganglion cell axon guidance [GO:0031290]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; toxin transport [GO:1901998]; trigeminal ganglion development [GO:0061551]; trigeminal nerve structural organization [GO:0021637]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; VEGF-activated neuropilin signaling pathway [GO:0038190]; VEGF-activated neuropilin signaling pathway involved in axon guidance [GO:1902378]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]	beta-galactosidase complex [GO:0009341]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; early endosome [GO:0005769]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of postsynaptic membrane [GO:0099055]; neurofilament [GO:0005883]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; semaphorin receptor complex [GO:0002116]; sorting endosome [GO:0097443]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	coreceptor activity [GO:0015026]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; GTPase activator activity [GO:0005096]; heparin binding [GO:0008201]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901]; semaphorin receptor activity [GO:0017154]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]
d3vdbd3_d2gdva2__1			Proteobacteria	Actinobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	sucrose phosphorylase activity [GO:0009018]; cellular carbohydrate metabolic process [GO:0044262]	lactose catabolic process [GO:0005990]	cellular carbohydrate metabolic process [GO:0044262]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	sucrose phosphorylase activity [GO:0009018]
d3vdca1_d1ryyg1__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alpha-amino-acid esterase activity [GO:0047658]; dipeptidyl-peptidase activity [GO:0008239]
d3vdca2_d1jyzi2__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3vdca3_d4x0vh___1			Proteobacteria	Firmicutes	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3vdca5_d3lppa1__1		Metazoa	Proteobacteria	Chordata	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	beta-galactosidase complex [GO:0009341]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]
d3vdcb4_d3t0bd2__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vdcc4_d1jz0g1__1			Proteobacteria		beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]		alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	
d3vdcd4_d3muy42__1			Proteobacteria	Proteobacteria	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	lactose catabolic process [GO:0005990]	beta-galactosidase complex [GO:0009341]	beta-galactosidase complex [GO:0009341]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vdqc__d5vkra2__1		Metazoa	Proteobacteria	Chordata	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d3ve3a__d3c2we3__1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3ve9a__d3bpwa1__1			Crenarchaeota	Apicomplexa	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3veca__d2cg4b2__1			Actinobacteria	Proteobacteria	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	amino acid binding [GO:0016597]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; response to amino acid [GO:0043200]		negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; response to amino acid [GO:0043200]			heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	amino acid binding [GO:0016597]; DNA-binding transcription factor activity [GO:0003700]; sequence-specific DNA binding [GO:0043565]
d3vefb__d1tr0f___1		Viridiplantae	Actinobacteria	Streptophyta	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	
d3vegb__d1tr0t___1		Viridiplantae	Actinobacteria	Streptophyta	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]						heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	
d3veqa__d3i29b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d3veqb__d1ucy.2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	digestion [GO:0007586]; proteolysis [GO:0006508]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; protein polymerization [GO:0051258]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; fibrinogen binding [GO:0070051]; serine-type endopeptidase activity [GO:0004252]
d3veva2_d3p4ib1__1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	cytoplasm [GO:0005737]; acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	acetyl-CoA biosynthetic process [GO:0006085]; organic acid metabolic process [GO:0006082]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]	acetate kinase activity [GO:0008776]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]
d3veva2_d5aqma1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3veya1_d1dgkn1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]; canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	canonical glycolysis [GO:0061621]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; maintenance of protein location in mitochondrion [GO:0072656]; mannose metabolic process [GO:0006013]; positive regulation of cytokine secretion involved in immune response [GO:0002741]; positive regulation of interleukin-1 beta secretion [GO:0050718]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytosol [GO:0005829]; membrane raft [GO:0045121]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; identical protein binding [GO:0042802]; mannokinase activity [GO:0019158]; peptidoglycan binding [GO:0042834]
d3veya2_d2ap1a1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]; zinc ion binding [GO:0008270]; N-acetylglucosamine metabolic process [GO:0006044]; peptidoglycan turnover [GO:0009254]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	N-acetylglucosamine metabolic process [GO:0006044]; peptidoglycan turnover [GO:0009254]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]		ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]	ATP binding [GO:0005524]; N-acetylglucosamine kinase activity [GO:0045127]; zinc ion binding [GO:0008270]
d3vf7a__d5p4ea___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3vf7b__d1fkna___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3vfaa__d3pb5a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3vfbb__d5jfpa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3vfca2_d3tjid2__1			Actinobacteria	Proteobacteria	glucarate dehydratase activity [GO:0008872]	magnesium ion binding [GO:0000287]; cellular amino acid catabolic process [GO:0009063]		cellular amino acid catabolic process [GO:0009063]			glucarate dehydratase activity [GO:0008872]	magnesium ion binding [GO:0000287]
d3vfea__d2d2db___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]; serine-type endopeptidase activity [GO:0004252]; amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	amyloid precursor protein metabolic process [GO:0042982]; central nervous system development [GO:0007417]; collagen catabolic process [GO:0030574]; hormone metabolic process [GO:0042445]; myelination [GO:0042552]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; protein autoprocessing [GO:0016540]; regulation of cell differentiation [GO:0045595]; regulation of neuron projection development [GO:0010975]; response to wounding [GO:0009611]; tissue regeneration [GO:0042246]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; secretory granule [GO:0030141]	cytoplasmic viral factory [GO:0039714]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]; endonuclease activity [GO:0004519]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3vfgl2_d4y5xa___1		Metazoa		Chordata		extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]		brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]		extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]		erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]
d3vfia__d1xzoa1__1				Firmicutes	protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]; plasma membrane [GO:0005886]	protein disulfide oxidoreductase activity [GO:0015035]	metal ion binding [GO:0046872]
d3vfqa1_d5cb5c___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; protein ADP-ribosylase activity [GO:1990404]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]; negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]	negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; protein ADP-ribosylase activity [GO:1990404]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]
d3vfqa2_d5dusa1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; protein ADP-ribosylase activity [GO:1990404]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; protein ADP-ribosylase activity [GO:1990404]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3vg0l1_d5lhqb1__1		Metazoa		Chordata		cell surface [GO:0009986]; extracellular space [GO:0005615]; membrane [GO:0016020]; peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]; angiogenesis [GO:0001525]; fibrinolysis [GO:0042730]; neuron death [GO:0070997]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ovulation [GO:0060279]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell migration [GO:0014911]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of hepatocyte proliferation [GO:2000345]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; response to hypoxia [GO:0001666]; skeletal muscle tissue regeneration [GO:0043403]; smooth muscle cell migration [GO:0014909]; wound healing [GO:0042060]		angiogenesis [GO:0001525]; fibrinolysis [GO:0042730]; neuron death [GO:0070997]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ovulation [GO:0060279]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of smooth muscle cell migration [GO:0014911]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of hepatocyte proliferation [GO:2000345]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; response to hypoxia [GO:0001666]; skeletal muscle tissue regeneration [GO:0043403]; smooth muscle cell migration [GO:0014909]; wound healing [GO:0042060]		cell surface [GO:0009986]; extracellular space [GO:0005615]; membrane [GO:0016020]		peptidase activity [GO:0008233]; serine-type endopeptidase activity [GO:0004252]
d3vg2a1_d1gt5b___1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]; small molecule binding [GO:0036094]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]	small molecule binding [GO:0036094]
d3vg5a1_d1yupd___1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]		apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	extracellular region [GO:0005576]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]
d3vg6a1_d1rlbe___1	Metazoa	Metazoa	Chordata	Chordata	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; intestinal absorption [GO:0050892]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of hydrolase activity [GO:0051345]; regulation of lipid metabolic process [GO:0019216]; triglyceride catabolic process [GO:0019433]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	apical cortex [GO:0045179]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; peroxisomal matrix [GO:0005782]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; bile acid binding [GO:0032052]; chromatin binding [GO:0003682]; drug binding [GO:0008144]; fatty acid binding [GO:0005504]; long-chain fatty acid transporter activity [GO:0005324]; phospholipid binding [GO:0005543]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d3vg9b1_d1bfoc2__1	Metazoa	Metazoa	Chordata	Chordata	axolemma [GO:0030673]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; intermediate filament [GO:0005882]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; alpha-actinin binding [GO:0051393]; enzyme binding [GO:0019899]; G protein-coupled adenosine receptor activity [GO:0001609]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; type 5 metabotropic glutamate receptor binding [GO:0031802]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; cellular protein metabolic process [GO:0044267]; central nervous system development [GO:0007417]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of transcription, DNA-templated [GO:0006355]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; sensory perception [GO:0007600]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; cellular protein metabolic process [GO:0044267]; central nervous system development [GO:0007417]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of transcription, DNA-templated [GO:0006355]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; sensory perception [GO:0007600]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	axolemma [GO:0030673]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; intermediate filament [GO:0005882]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	alpha-actinin binding [GO:0051393]; enzyme binding [GO:0019899]; G protein-coupled adenosine receptor activity [GO:0001609]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; type 5 metabotropic glutamate receptor binding [GO:0031802]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3vg9b2_d4wi5a1__1	Metazoa	Metazoa	Chordata	Chordata	axolemma [GO:0030673]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; intermediate filament [GO:0005882]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; alpha-actinin binding [GO:0051393]; enzyme binding [GO:0019899]; G protein-coupled adenosine receptor activity [GO:0001609]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; type 5 metabotropic glutamate receptor binding [GO:0031802]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; cellular protein metabolic process [GO:0044267]; central nervous system development [GO:0007417]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of transcription, DNA-templated [GO:0006355]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; sensory perception [GO:0007600]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; cellular protein metabolic process [GO:0044267]; central nervous system development [GO:0007417]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of transcription, DNA-templated [GO:0006355]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; sensory perception [GO:0007600]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	axolemma [GO:0030673]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; intermediate filament [GO:0005882]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	alpha-actinin binding [GO:0051393]; enzyme binding [GO:0019899]; G protein-coupled adenosine receptor activity [GO:0001609]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; type 5 metabotropic glutamate receptor binding [GO:0031802]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3vgab1_d6b3sg2__1	Metazoa	Metazoa	Chordata	Chordata	axolemma [GO:0030673]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; intermediate filament [GO:0005882]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]; alpha-actinin binding [GO:0051393]; enzyme binding [GO:0019899]; G protein-coupled adenosine receptor activity [GO:0001609]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; type 5 metabotropic glutamate receptor binding [GO:0031802]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; cellular protein metabolic process [GO:0044267]; central nervous system development [GO:0007417]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of transcription, DNA-templated [GO:0006355]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; sensory perception [GO:0007600]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; blood circulation [GO:0008015]; blood coagulation [GO:0007596]; cell-cell signaling [GO:0007267]; cellular defense response [GO:0006968]; cellular protein metabolic process [GO:0044267]; central nervous system development [GO:0007417]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled receptor signaling pathway [GO:0007186]; inflammatory response [GO:0006954]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of transcription, DNA-templated [GO:0006355]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; sensory perception [GO:0007600]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	axolemma [GO:0030673]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; intermediate filament [GO:0005882]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynaptic active zone [GO:0048786]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	alpha-actinin binding [GO:0051393]; enzyme binding [GO:0019899]; G protein-coupled adenosine receptor activity [GO:0001609]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; type 5 metabotropic glutamate receptor binding [GO:0031802]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d3vgba1_d1soxa1__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	trehalose biosynthetic process [GO:0005992]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	cytoplasm [GO:0005737]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]
d3vgda2_d2ebna___1			Crenarchaeota	Bacteroidetes	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	extracellular region [GO:0005576]; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]; carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]
d3vgda2_d2pwfb1__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3vgea1_d4iefd2__1			Crenarchaeota	Bacteroidetes	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; pathogenesis [GO:0009405]; proteolysis [GO:0006508]	trehalose biosynthetic process [GO:0005992]	pathogenesis [GO:0009405]; proteolysis [GO:0006508]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]
d3vgfa1_d1ut9a2__1			Crenarchaeota	Firmicutes	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose catabolic process [GO:0030245]	trehalose biosynthetic process [GO:0005992]	cellulose catabolic process [GO:0030245]	cytoplasm [GO:0005737]		4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	cellulase activity [GO:0008810]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]
d3vgfa2_d3l2la1__1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	trehalose biosynthetic process [GO:0005992]	carbohydrate catabolic process [GO:0016052]	cytoplasm [GO:0005737]	extracellular space [GO:0005615]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3vgfa3_d2zx7b2__1			Crenarchaeota	Thermotogae	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	trehalose biosynthetic process [GO:0005992]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	cytoplasm [GO:0005737]	lysosome [GO:0005764]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	alpha-L-fucosidase activity [GO:0004560]
d3vgga3_d4lpcb3__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	cytosol [GO:0005829]; 1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; glycogen biosynthetic process [GO:0005978]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	1,4-alpha-glucan branching enzyme activity [GO:0003844]; 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) [GO:0102752]; cation binding [GO:0043169]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3vgha1_d1d3ca1__1			Crenarchaeota	Firmicutes	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3vgha1_d1im3d___1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	trehalose biosynthetic process [GO:0005992]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytoplasm [GO:0005737]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3vgha2_d3vdcb3__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	trehalose biosynthetic process [GO:0005992]	lactose catabolic process [GO:0005990]	cytoplasm [GO:0005737]	beta-galactosidase complex [GO:0009341]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vgha2_d4maza1__1			Crenarchaeota	Firmicutes	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	cytoplasm [GO:0005737]; alpha-amylase activity [GO:0004556]; metal ion binding [GO:0046872]; oligo-1,6-glucosidase activity [GO:0004574]; oligosaccharide catabolic process [GO:0009313]	trehalose biosynthetic process [GO:0005992]	oligosaccharide catabolic process [GO:0009313]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	alpha-amylase activity [GO:0004556]; metal ion binding [GO:0046872]; oligo-1,6-glucosidase activity [GO:0004574]
d3vgha3_d2pwga2__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]; trehalose biosynthetic process [GO:0005992]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	trehalose biosynthetic process [GO:0005992]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity [GO:0033942]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3vgjb__d3q12c1__1			Apicomplexa	Proteobacteria	host cell cytosol [GO:0044164]; ATP binding [GO:0005524]; host cell surface receptor binding [GO:0046789]; tyrosine-tRNA ligase activity [GO:0004831]; tyrosyl-tRNA aminoacylation [GO:0006437]	cytosol [GO:0005829]; ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]; pantothenate biosynthetic process from valine [GO:0033317]	tyrosyl-tRNA aminoacylation [GO:0006437]	pantothenate biosynthetic process from valine [GO:0033317]	host cell cytosol [GO:0044164]	cytosol [GO:0005829]	ATP binding [GO:0005524]; host cell surface receptor binding [GO:0046789]; tyrosine-tRNA ligase activity [GO:0004831]	ATP binding [GO:0005524]; pantoate-beta-alanine ligase activity [GO:0004592]
d3vgna__d4r9ka___1			Proteobacteria	Actinobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	limonene-1,2-epoxide hydrolase activity [GO:0018744]	steroid metabolic process [GO:0008202]				steroid delta-isomerase activity [GO:0004769]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d3vgnb__d4xdvd___1			Proteobacteria	Actinobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	limonene-1,2-epoxide hydrolase activity [GO:0018744]	steroid metabolic process [GO:0008202]				steroid delta-isomerase activity [GO:0004769]	limonene-1,2-epoxide hydrolase activity [GO:0018744]
d3vgoa3_d1a09b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]; cell surface receptor signaling pathway [GO:0007166]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; NLS-bearing protein import into nucleus [GO:0006607]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; signal transduction [GO:0007165]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cell surface receptor signaling pathway [GO:0007166]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; NLS-bearing protein import into nucleus [GO:0006607]; regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000583]; signal transduction [GO:0007165]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cytosol [GO:0005829]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	calcium ion binding [GO:0005509]; phosphotyrosine residue binding [GO:0001784]; receptor tyrosine kinase binding [GO:0030971]; SH3 domain binding [GO:0017124]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]
d3vgwa__d2y32d___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]; antibacterial humoral response [GO:0019731]	biotin binding [GO:0009374]	antibacterial humoral response [GO:0019731]		extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3vgwg__d1hy2d___1	Metazoa		Chordata	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]; antibacterial humoral response [GO:0019731]	extracellular region [GO:0005576]; biotin binding [GO:0009374]	antibacterial humoral response [GO:0019731]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3vh8b__d5t1dl1__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; carbohydrate binding [GO:0030246]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	viral process [GO:0016032]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]
d3vh8e__d1m71b2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3vhfa__d2ahna___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasmic vesicle [GO:0031410]	extracellular region [GO:0005576]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; IgE binding [GO:0019863]; metabolic process [GO:0008152]		metabolic process [GO:0008152]	cytoplasmic vesicle [GO:0031410]	extracellular region [GO:0005576]		glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; IgE binding [GO:0019863]
d3vhga__d3n03a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]			cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]		
d3vhib__d5n8ta___1	Metazoa		Chordata	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]; antibacterial humoral response [GO:0019731]	extracellular region [GO:0005576]; biotin binding [GO:0009374]	antibacterial humoral response [GO:0019731]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3vhmb__d4z2oa___1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]; antibacterial humoral response [GO:0019731]	extracellular region [GO:0005576]; biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]	antibacterial humoral response [GO:0019731]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]; protein homodimerization activity [GO:0042803]
d3vhmc__d4bj8m___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]; antibacterial humoral response [GO:0019731]	biotin binding [GO:0009374]	antibacterial humoral response [GO:0019731]		extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3vhxe1_d2jj2l2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centralspindlin complex [GO:0097149]; centrosome [GO:0005813]; cytosol [GO:0005829]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; intercellular bridge [GO:0045171]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]; actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]	ATP synthesis coupled proton transport [GO:0015986]	cell [GO:0005623]; centralspindlin complex [GO:0097149]; centrosome [GO:0005813]; cytosol [GO:0005829]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; intercellular bridge [GO:0045171]; kinesin complex [GO:0005871]; microtubule [GO:0005874]; midbody [GO:0030496]; mitotic spindle [GO:0072686]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATPase activity [GO:0016887]; ATP binding [GO:0005524]; microtubule binding [GO:0008017]; microtubule motor activity [GO:0003777]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3vi2a__d1losc___1			Apicomplexa	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3vi2b__d3p61a___1			Apicomplexa	Euryarchaeota	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; pyrimidine nucleotide biosynthetic process [GO:0006221]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]			orotidine-5'-phosphate decarboxylase activity [GO:0004590]	orotidine-5'-phosphate decarboxylase activity [GO:0004590]
d3vi3e1_d2ak4t1__1	Metazoa	Metazoa	Chordata	Chordata	alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integrin alpha5-beta1 complex [GO:0034674]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]; epidermal growth factor receptor binding [GO:0005154]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor receptor binding [GO:0005161]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; angiogenesis [GO:0001525]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory [GO:0007613]; negative regulation of anoikis [GO:2000811]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; wound healing, spreading of epidermal cells [GO:0035313]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	angiogenesis [GO:0001525]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory [GO:0007613]; negative regulation of anoikis [GO:2000811]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; wound healing, spreading of epidermal cells [GO:0035313]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integrin alpha5-beta1 complex [GO:0034674]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	epidermal growth factor receptor binding [GO:0005154]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor receptor binding [GO:0005161]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3vi3l1_d2q86a1__1	Metazoa	Metazoa	Chordata	Chordata	alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integrin alpha5-beta1 complex [GO:0034674]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]; epidermal growth factor receptor binding [GO:0005154]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor receptor binding [GO:0005161]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]; angiogenesis [GO:0001525]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory [GO:0007613]; negative regulation of anoikis [GO:2000811]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; wound healing, spreading of epidermal cells [GO:0035313]	integral component of membrane [GO:0016021]	angiogenesis [GO:0001525]; CD40 signaling pathway [GO:0023035]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-cell adhesion mediated by integrin [GO:0033631]; cell-substrate adhesion [GO:0031589]; cell-substrate junction assembly [GO:0007044]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory [GO:0007613]; negative regulation of anoikis [GO:2000811]; positive regulation of cell migration [GO:0030335]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; wound healing, spreading of epidermal cells [GO:0035313]		alphav-beta3 integrin-vitronectin complex [GO:0071062]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; endoplasmic reticulum [GO:0005783]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integrin alpha5-beta1 complex [GO:0034674]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	epidermal growth factor receptor binding [GO:0005154]; integrin binding [GO:0005178]; metal ion binding [GO:0046872]; platelet-derived growth factor receptor binding [GO:0005161]; vascular endothelial growth factor receptor 2 binding [GO:0043184]; virus receptor activity [GO:0001618]	
d3vi5b1_d1ev9a2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]; aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	aging [GO:0007568]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; prostaglandin metabolic process [GO:0006693]; response to drug [GO:0042493]; response to nutrient levels [GO:0031667]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; nuclear outer membrane [GO:0005640]; nucleus [GO:0005634]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein homodimerization activity [GO:0042803]; steroid delta-isomerase activity [GO:0004769]
d3vi5b2_d1px7a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3vi5c1_d3ik9b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3vi7a1_d5l6xb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3vi7a2_d2wdub2__1	Metazoa	Metazoa	Chordata	Platyhelminthes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	glutathione transferase activity [GO:0004364]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	glutathione transferase activity [GO:0004364]
d3vi7b1_d3dd3b1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3vi7c1_d1o81a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]; cell redox homeostasis [GO:0045454]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cell [GO:0005623]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	
d3vi7c2_d4iw9b2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]		calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	
d3vi7d2_d3gusb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3vifa__d4do4b1__1	Metazoa	Metazoa	Arthropoda	Chordata	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d3viha__d4do4a1__1	Metazoa	Metazoa	Arthropoda	Chordata	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]; carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]; glycosylceramide catabolic process [GO:0046477]; oligosaccharide metabolic process [GO:0009311]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; lysosome [GO:0005764]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	alpha-galactosidase activity [GO:0004557]; alpha-N-acetylgalactosaminidase activity [GO:0008456]; protein homodimerization activity [GO:0042803]
d3viia__d3gbea1__1	Metazoa		Arthropoda	Proteobacteria	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	isomaltulose synthase activity [GO:0050006]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	isomaltulose synthase activity [GO:0050006]
d3vika__d1ug6a___1	Metazoa		Arthropoda	Deinococcus-Thermus	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3vila__d2d20b1__1	Metazoa		Arthropoda	Actinobacteria	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	endo-1,4-beta-xylanase activity [GO:0031176]
d3vina__d3t2qa3__1	Metazoa		Arthropoda	Proteobacteria	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vioa__d2x05b3__1	Metazoa		Arthropoda	Actinobacteria	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3vipa__d1f49e5__1	Metazoa		Arthropoda		beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	
d3vj7a__d1tfoa___1			Proteobacteria	Proteobacteria	endonuclease activity [GO:0004519]; ribonuclease activity [GO:0004540]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	extrachromosomal circular DNA [GO:0005727]; ribonuclease activity [GO:0004540]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]		extrachromosomal circular DNA [GO:0005727]	endonuclease activity [GO:0004519]; ribonuclease activity [GO:0004540]	ribonuclease activity [GO:0004540]
d3vjbb__d5imia___1	Metazoa	Fungi	Chordata	Ascomycota	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]		farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]
d3vjca__d4kvdd___1	Metazoa	Fungi	Chordata	Ascomycota	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]		farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]
d3vjcb__d3wcld___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d3vjcc__d4demf___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3vjcd__d3wega___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d3vjka2_d2vjdb___1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	acetylcholine catabolic process in synaptic cleft [GO:0001507]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	acetylcholinesterase activity [GO:0003990]
d3vjla2_d2gbfa2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3vjlb2_d1uwcb1__1	Metazoa	Fungi	Chordata	Ascomycota	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]; cell wall macromolecule catabolic process [GO:0016998]; cellulose catabolic process [GO:0030245]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellulose catabolic process [GO:0030245]; cell wall macromolecule catabolic process [GO:0016998]; lipid metabolic process [GO:0006629]; pectin catabolic process [GO:0045490]; xylan catabolic process [GO:0045493]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	cellulose binding [GO:0030248]; feruloyl esterase activity [GO:0030600]
d3vjmb2_d2ajdb2__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	dipeptidyl-peptidase activity [GO:0008239]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3vk0a__d4f8da___1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]	DNA binding [GO:0003677]					DNA binding [GO:0003677]	DNA binding [GO:0003677]
d3vk9a1_d5a5kq1__1	Metazoa	Viridiplantae	Arthropoda	Streptophyta	transferase activity [GO:0016740]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	transferase activity [GO:0016740]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d3vk9b1_d1quwa___1	Metazoa		Arthropoda	Firmicutes	transferase activity [GO:0016740]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]	transferase activity [GO:0016740]	protein disulfide oxidoreductase activity [GO:0015035]
d3vk9c1_d6gssa2__1	Metazoa	Metazoa	Arthropoda	Chordata	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	transferase activity [GO:0016740]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3vk9d2_d1gsub1__1	Metazoa	Metazoa	Arthropoda	Chordata	transferase activity [GO:0016740]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]		cytosol [GO:0005829]; intercellular bridge [GO:0045171]	transferase activity [GO:0016740]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d3vkla1_d1s0ga1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	negative regulation of neurotransmitter secretion [GO:0046929]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d3vklb1_d1qu0c___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]; signaling receptor binding [GO:0005102]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; Schwann cell differentiation [GO:0014037]; tissue development [GO:0009888]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; dendritic spine [GO:0043197]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuromuscular junction [GO:0031594]; sarcolemma [GO:0042383]; synaptic cleft [GO:0043083]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	signaling receptor binding [GO:0005102]
d3vkma1_d2exja1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]		carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3vkmb1_d1gica___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]		cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]		carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3vksa1_d3b0ha1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3vksa3_d3mm9d1__1	Viridiplantae		Streptophyta	Euryarchaeota	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]		sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d3vkta3_d3mmae1__1	Viridiplantae		Streptophyta	Euryarchaeota	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]		sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d3vkud2_d4wlnb2__1		Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d3vkue1_d1ie3d1__1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]		L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]
d3vkue1_d1ntob2__1				Crenarchaeota		alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]						alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]
d3vkva2_d1guzd2__1				Chlorobi		L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]		carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]				L-malate dehydrogenase activity [GO:0030060]
d3vkva2_d1v6aa2__1		Metazoa		Chordata		cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]
d3vkvb2_d1ldnb2__1				Firmicutes		cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d3vkvd2_d3u95d2__1				Thermotogae		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3vl8a__d5gltb1__1	Fungi	Metazoa	Ascomycota	Nematoda (roundworms)	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]		cellulase activity [GO:0008810]; xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]	carbohydrate binding [GO:0030246]
d3vl9b__d1g9ba1__1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]; cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cell wall organization [GO:0071555]; polysaccharide catabolic process [GO:0000272]	negative regulation of neurotransmitter secretion [GO:0046929]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	cellulase activity [GO:0008810]; xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d3vlbd__d2arba___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	aspartic-type endopeptidase activity [GO:0004190]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					aspartic-type endopeptidase activity [GO:0004190]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3vlhb1_d4a5gb___1		Viridiplantae	Euryarchaeota	Streptophyta	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]		extracellular region [GO:0005576]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3vlhb2_d3hdla___1		Viridiplantae	Euryarchaeota	Streptophyta	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]		extracellular region [GO:0005576]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3vlib1_d5v4oa2__1			Euryarchaeota	Proteobacteria	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]			catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3vlkb2_d1a2ga___1		Fungi	Euryarchaeota	Ascomycota	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3vlla2_d1h57a___1		Viridiplantae	Euryarchaeota	Streptophyta	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]		extracellular region [GO:0005576]; vacuole [GO:0005773]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3vlmb2_d2vnzx___1		Viridiplantae	Euryarchaeota	Streptophyta	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		chloroplast [GO:0009507]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3vlmb2_d3vlhb1__1			Euryarchaeota	Euryarchaeota	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]			catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3vlna1_d2c3ta1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]
d3vlna2_d1g7oa1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytosol [GO:0005829]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; glutathione oxidoreductase activity [GO:0097573]; cell redox homeostasis [GO:0045454]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cell [GO:0005623]; cytosol [GO:0005829]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; glutathione oxidoreductase activity [GO:0097573]
d3vlva__d2f35a___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]; drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]; synaptic transmission, glutamatergic [GO:0035249]		cell junction [GO:0030054]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; receptor complex [GO:0043235]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]	drug binding [GO:0008144]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate binding [GO:0016595]; glutamate receptor activity [GO:0008066]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; voltage-gated cation channel activity [GO:0022843]
d3vlwa__d5fhma___1		Metazoa	Proteobacteria	Chordata	metal ion binding [GO:0046872]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3vlxa1_d1zj8b2__1	Viridiplantae		Streptophyta	Actinobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]		cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]		cell wall [GO:0005618]; cytosol [GO:0005829]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]
d3vlxa2_d2akja4__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	chloroplast [GO:0009507]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate assimilation [GO:0042128]		nitrate assimilation [GO:0042128]		chloroplast [GO:0009507]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3vlxa3_d1zj9a1__1	Viridiplantae		Streptophyta	Actinobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]		cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]		cell wall [GO:0005618]; cytosol [GO:0005829]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]
d3vlxa4_d3b0hb4__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3vlya1_d1zj9a2__1	Viridiplantae		Streptophyta	Actinobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; cytosol [GO:0005829]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]		cysteine biosynthetic process from serine [GO:0006535]; sulfate assimilation [GO:0000103]		cell wall [GO:0005618]; cytosol [GO:0005829]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase activity [GO:0016002]
d3vlya1_d3vkta3__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3vlya3_d4g39a3__1	Viridiplantae		Streptophyta	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfite reductase complex (NADPH) [GO:0009337]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]		cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]		sulfite reductase complex (NADPH) [GO:0009337]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]
d3vlya4_d4aopa4__1	Viridiplantae		Streptophyta	Proteobacteria	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	sulfite reductase complex (NADPH) [GO:0009337]; 4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]		cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]		sulfite reductase complex (NADPH) [GO:0009337]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; sulfite reductase (ferredoxin) activity [GO:0050311]; sulfite reductase (NADPH) activity [GO:0004783]; sulfite reductase activity [GO:0016002]
d3vlza3_d2akja2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	chloroplast [GO:0009507]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitrate assimilation [GO:0042128]		nitrate assimilation [GO:0042128]		chloroplast [GO:0009507]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3vlza4_d3vksa2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3vm0a1_d3mm7e1__1	Viridiplantae		Streptophyta	Euryarchaeota	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	membrane [GO:0016020]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]; sulfur compound metabolic process [GO:0006790]		sulfur compound metabolic process [GO:0006790]		membrane [GO:0016020]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydrogensulfite reductase activity [GO:0018551]; metal ion binding [GO:0046872]
d3vm0a2_d3vlya4__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3vm1a4_d3b0ja2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]					4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; ferredoxin-nitrite reductase activity [GO:0048307]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3vm4a__d2zuha___1			Proteobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3vm5a2_d1hl9a1__1	Metazoa		Chordata	Thermotogae	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]		lysosome [GO:0005764]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	alpha-L-fucosidase activity [GO:0004560]
d3vm5a2_d2zx7a2__1	Metazoa		Chordata	Thermotogae	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]		lysosome [GO:0005764]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]	alpha-L-fucosidase activity [GO:0004560]
d3vm7a1_d5idia___1	Fungi		Ascomycota	Thermotogae	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	glucan 1,4-beta-glucosidase activity [GO:0031217]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate catabolic process [GO:0016052]	cellulose catabolic process [GO:0030245]			alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	glucan 1,4-beta-glucosidase activity [GO:0031217]; scopolin beta-glucosidase activity [GO:0102483]
d3vm8b__d3ex8a1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; viral process [GO:0016032]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; viral process [GO:0016032]	riboflavin biosynthetic process [GO:0009231]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]		cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]
d3vmfa2_d1ob5a1__1			Crenarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3vmfa3_d1efuc2__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3vmja1_d3mbca___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]		3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]
d3vmkb1_d1td9e___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	cytoplasm [GO:0005737]; phosphate acetyltransferase activity [GO:0008959]; acetyl-CoA biosynthetic process [GO:0006085]	leucine biosynthetic process [GO:0009098]	acetyl-CoA biosynthetic process [GO:0006085]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	phosphate acetyltransferase activity [GO:0008959]
d3vnga__d4n1bc___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]; cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]; cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]	disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]	disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]
d3vnha__d2vpja___1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]; cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	centriolar satellite [GO:0034451]; COPII vesicle coat [GO:0030127]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; identical protein binding [GO:0042802]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055]	cellular response to interleukin-4 [GO:0071353]; cellular response to oxidative stress [GO:0034599]; cytoplasmic sequestering of transcription factor [GO:0042994]; in utero embryonic development [GO:0001701]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; post-translational protein modification [GO:0043687]; protein deubiquitination [GO:0016579]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of epidermal cell differentiation [GO:0045604]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055]	actin filament [GO:0005884]; centriolar satellite [GO:0034451]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; inclusion body [GO:0016234]; midbody [GO:0030496]; nucleoplasm [GO:0005654]	centriolar satellite [GO:0034451]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; COPII vesicle coat [GO:0030127]; Cul3-RING ubiquitin ligase complex [GO:0031463]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]	disordered domain specific binding [GO:0097718]; protein homodimerization activity [GO:0042803]; transcription factor binding [GO:0008134]	identical protein binding [GO:0042802]
d3vnoa__d2wi9b___1			Proteobacteria	Actinobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]		macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]			heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d3vnpb1_d3gvda___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; serine O-acetyltransferase activity [GO:0009001]; cysteine biosynthetic process from serine [GO:0006535]		cysteine biosynthetic process from serine [GO:0006535]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	serine O-acetyltransferase activity [GO:0009001]
d3vnwa__d4eiea___1			Deinococcus-Thermus	Cyanobacteria	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]					electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3vnxa__d3wnwj___1	Viridiplantae	Metazoa	Chlorophyta	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d3vo1a2_d1fb3a4__1	Viridiplantae		Streptophyta		chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]				chloroplast [GO:0009507]		ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	
d3vo1b1_d3w5ha1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]		cholesterol biosynthetic process [GO:0006695]	chloroplast [GO:0009507]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d3vo2b2_d1fdra2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; FAD binding [GO:0071949]; ferredoxin-NADP+ reductase activity [GO:0004324]; oxidoreductase activity [GO:0016491]; fructose catabolic process [GO:0006001]; iron-sulfur cluster assembly [GO:0016226]; response to drug [GO:0042493]; response to superoxide [GO:0000303]		fructose catabolic process [GO:0006001]; iron-sulfur cluster assembly [GO:0016226]; response to drug [GO:0042493]; response to superoxide [GO:0000303]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	FAD binding [GO:0071949]; ferredoxin-NADP+ reductase activity [GO:0004324]; oxidoreductase activity [GO:0016491]
d3vo8b2_d4zhqa2__1		Metazoa	Firmicutes	Chordata	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]; tubulin binding [GO:0015631]; microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	tubulin binding [GO:0015631]
d3voaa1_d1w5ea1__1			Firmicutes	Euryarchaeota	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cell division [GO:0051301]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d3vodb__d2fbia1__1			Proteobacteria	Proteobacteria	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; cellular response to antibiotic [GO:0071236]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to heat [GO:0009408]	DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]	cellular response to antibiotic [GO:0071236]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; response to heat [GO:0009408]	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]			DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]	DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]
d3vofa__d3a9aa___1	Fungi		Basidiomycota		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	
d3voga1_d5jx5c___1	Fungi	Fungi	Basidiomycota	Chytridiomycota	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3voja1_d3voia1__1	Fungi	Fungi	Basidiomycota	Basidiomycota	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3voma__d1gc3b___1			Actinobacteria	Deinococcus-Thermus	extracellular region [GO:0005576]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; alanine-glyoxylate transaminase activity [GO:0008453]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; L-serine biosynthetic process [GO:0006564]; pyridoxine biosynthetic process [GO:0008615]	cytoplasm [GO:0005737]; aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]; biosynthetic process [GO:0009058]	glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; L-serine biosynthetic process [GO:0006564]; pyridoxine biosynthetic process [GO:0008615]	biosynthetic process [GO:0009058]	extracellular region [GO:0005576]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	alanine-glyoxylate transaminase activity [GO:0008453]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]	aspartate-prephenate aminotransferase activity [GO:0033853]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; pyridoxal phosphate binding [GO:0030170]
d3vong__d5hptf___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]; protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cellular protein modification process [GO:0006464]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to insecticide [GO:0017085]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; lysosomal membrane [GO:0005765]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; synapse [GO:0045202]; vesicle [GO:0031982]	ubiquitin conjugating enzyme activity [GO:0061631]	protein tag [GO:0031386]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d3voni__d2dmfa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein ubiquitination [GO:0016567]	DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]	cytosol [GO:0005829]; nucleus [GO:0005634]	ubiquitin conjugating enzyme activity [GO:0061631]	metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]
d3vonq__d2daya1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein ubiquitination [GO:0016567]	DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]	cytosol [GO:0005829]; nucleus [GO:0005634]	ubiquitin conjugating enzyme activity [GO:0061631]	metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]
d3vonq__d4r62a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translation [GO:0006412]; translational initiation [GO:0006413]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; viral transcription [GO:0019083]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; small ribosomal subunit [GO:0015935]; vesicle [GO:0031982]	ubiquitin conjugating enzyme activity [GO:0061631]	metal ion binding [GO:0046872]; protein tag [GO:0031386]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735]; ubiquitin protein ligase binding [GO:0031625]
d3vonr__d3h8ka___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cytosol [GO:0005829]; dendrite [GO:0030425]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; BAT3 complex binding [GO:1904288]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-specific protease binding [GO:1990381]; ubiquitin-ubiquitin ligase activity [GO:0034450]; aging [GO:0007568]; endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; learning or memory [GO:0007611]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of protein binding [GO:0032092]; protein autoubiquitination [GO:0051865]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	aging [GO:0007568]; endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; learning or memory [GO:0007611]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of protein binding [GO:0032092]; protein autoubiquitination [GO:0051865]; protein complex oligomerization [GO:0051259]; protein folding [GO:0006457]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]	cytosol [GO:0005829]; dendrite [GO:0030425]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum quality control compartment [GO:0044322]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	ubiquitin conjugating enzyme activity [GO:0061631]	BAT3 complex binding [GO:1904288]; chaperone binding [GO:0051087]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein binding, bridging [GO:0030674]; signaling receptor activity [GO:0038023]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-specific protease binding [GO:1990381]; ubiquitin-ubiquitin ligase activity [GO:0034450]
d3vons__d2y9ma1__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cytoplasm [GO:0005737]; integral component of peroxisomal membrane [GO:0005779]; protein membrane anchor [GO:0043495]; ubiquitin-protein transferase activator activity [GO:0097027]; positive regulation of protein autoubiquitination [GO:1902499]; positive regulation of protein ubiquitination [GO:0031398]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein targeting to peroxisome [GO:0006625]	DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	positive regulation of protein autoubiquitination [GO:1902499]; positive regulation of protein ubiquitination [GO:0031398]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein targeting to peroxisome [GO:0006625]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]	cytoplasm [GO:0005737]; integral component of peroxisomal membrane [GO:0005779]	ubiquitin conjugating enzyme activity [GO:0061631]	protein membrane anchor [GO:0043495]; ubiquitin-protein transferase activator activity [GO:0097027]
d3vons__d5ifra1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ubiquitin conjugating enzyme activity [GO:0061631]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3vonu__d1w4ua___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]; ubiquitin conjugating enzyme activity [GO:0061631]; DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	DNA double-strand break processing [GO:0000729]; double-strand break repair via nonhomologous end joining [GO:0006303]; error-free postreplication DNA repair [GO:0042275]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of DNA repair [GO:0045739]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of synapse assembly [GO:0051965]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA repair [GO:0006282]	cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; UBC13-MMS2 complex [GO:0031372]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	ubiquitin conjugating enzyme activity [GO:0061631]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]
d3vowa__d2z3jd___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; viral process [GO:0016032]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; viral process [GO:0016032]	response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]		cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d3vowb__d2b3jc___1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]; cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; viral process [GO:0016032]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]; tRNA wobble adenosine to inosine editing [GO:0002100]	cytidine deamination [GO:0009972]; cytidine to uridine editing [GO:0016554]; defense response to virus [GO:0051607]; DNA cytosine deamination [GO:0070383]; DNA demethylation [GO:0080111]; innate immune response [GO:0045087]; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869]; negative regulation of transposition [GO:0010529]; negative regulation of viral genome replication [GO:0045071]; viral process [GO:0016032]	tRNA wobble adenosine to inosine editing [GO:0002100]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; P-body [GO:0000932]		cytidine deaminase activity [GO:0004126]; deoxycytidine deaminase activity [GO:0047844]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	tRNA-specific adenosine-34 deaminase activity [GO:0052717]; zinc ion binding [GO:0008270]
d3vpab2_d4o2aa2__1		Metazoa	Firmicutes	Chordata	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d3vpda1_d2io9b1__1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]; cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glutathionylspermidine amidase activity [GO:0008884]; glutathionylspermidine synthase activity [GO:0008885]; metal ion binding [GO:0046872]; glutathione metabolic process [GO:0006749]; spermidine metabolic process [GO:0008216]	cellular protein modification process [GO:0006464]; lysine biosynthetic process via aminoadipic acid [GO:0019878]	glutathione metabolic process [GO:0006749]; spermidine metabolic process [GO:0008216]		cytosol [GO:0005829]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; glutathionylspermidine amidase activity [GO:0008884]; glutathionylspermidine synthase activity [GO:0008885]; metal ion binding [GO:0046872]
d3vpea__d1dd6b___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d3vpfb2_d3zznc2__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]
d3vpfc1_d4wlvd1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]		L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d3vpfc2_d2xxjd2__1				Deinococcus-Thermus		cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]
d3vpgb1_d1hdoa___1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; terminal bouton [GO:0043195]; biliverdin reductase activity [GO:0004074]; riboflavin reductase (NADPH) activity [GO:0042602]; heme catabolic process [GO:0042167]	glycolytic process [GO:0006096]	heme catabolic process [GO:0042167]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; terminal bouton [GO:0043195]	L-lactate dehydrogenase activity [GO:0004459]	biliverdin reductase activity [GO:0004074]; riboflavin reductase (NADPH) activity [GO:0042602]
d3vpgc1_d1up7h1__1			Deinococcus-Thermus	Thermotogae	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	6-phospho-beta-glucosidase activity [GO:0008706]; metal ion binding [GO:0046872]; methyl beta-D-glucoside 6-phosphate glucohydrolase activity [GO:0103047]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d3vpgd1_d1lehb1__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	glycolytic process [GO:0006096]	cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d3vphc1_d4wlnc1__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d3vpna1_d1xvfd___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3vpoa1_d2x172___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]
d3vpob1_d1fzhc___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; negative regulation of G0 to G1 transition [GO:0070317]; nucleobase-containing small molecule interconversion [GO:0015949]; protein heterotetramerization [GO:0051290]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]		ferric iron binding [GO:0008199]; protein homodimerization activity [GO:0042803]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3vpqa2_d2vctg2__1	Metazoa	Metazoa	Arthropoda	Chordata	transferase activity [GO:0016740]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]
d3vpqa2_d2wrtk2__1	Metazoa	Metazoa	Arthropoda	Platyhelminthes	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]				cytoplasm [GO:0005737]	transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]
d3vpta1_d4kh7b1__1	Metazoa		Arthropoda	Proteobacteria	transferase activity [GO:0016740]	transferase activity [GO:0016740]					transferase activity [GO:0016740]	transferase activity [GO:0016740]
d3vpta1_d6gswb2__1	Metazoa	Metazoa	Arthropoda	Chordata	transferase activity [GO:0016740]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]		glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]		cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	transferase activity [GO:0016740]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d3vpta2_d5a4ub2__1	Metazoa	Viridiplantae	Arthropoda	Streptophyta	transferase activity [GO:0016740]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	transferase activity [GO:0016740]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d3vpxa1_d2hk8g1__1			Firmicutes	Aquificae	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cellular amino acid metabolic process [GO:0006520]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d3vpxb1_d1bxgb2__1			Firmicutes	Actinobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	cellular amino acid metabolic process [GO:0006520]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]			nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d3vqla__d4ylcd1__1			Crenarchaeota	Crenarchaeota		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]						identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3vr6d2_d3ziac2__1		Fungi	Firmicutes	Ascomycota	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3vr6d3_d1efra1__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3vr6e1_d2jizh1__1		Metazoa	Firmicutes	Chordata	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3vr6e3_d3a5cm3__1			Firmicutes	Deinococcus-Thermus	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]			ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3vr8f1_d1n5wa2__1	Metazoa		Nematoda (roundworms)	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	tricarboxylic acid cycle [GO:0006099]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3vr9b1_d3b2fa___1	Metazoa	Viridiplantae	Nematoda (roundworms)	Streptophyta	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; electron transport chain [GO:0022900]; response to light stimulus [GO:0009416]	tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; response to light stimulus [GO:0009416]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3vr9f2_d2h88o2__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; respiratory electron transport chain [GO:0022904]; tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d3vrbb1_d2y5cb1__1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	mitochondrial matrix [GO:0005759]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; C21-steroid hormone biosynthetic process [GO:0006700]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	tricarboxylic acid cycle [GO:0006099]	C21-steroid hormone biosynthetic process [GO:0006700]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	mitochondrial matrix [GO:0005759]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3vrbf1_d2bs3b2__1	Metazoa		Nematoda (roundworms)	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]; tricarboxylic acid cycle [GO:0006099]	respirasome [GO:0070469]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) [GO:0005749]	respirasome [GO:0070469]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; ubiquinone binding [GO:0048039]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]
d3vrca__d1bbhb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3vrca__d3qvya___1			Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	
d3vrcb__d3m4bd___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3vrda1_d1kyod1__1		Fungi	Proteobacteria	Ascomycota	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity [GO:0016491]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3vrfa__d4gzga___1	Metazoa	Metazoa	Chordata	Annelida	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]			hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d3vrfb__d1y4vb___1	Metazoa	Metazoa	Chordata	Chordata	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3vrga__d1gvha1__1	Metazoa		Chordata	Proteobacteria	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; heme binding [GO:0020037]; hydroperoxide reductase activity [GO:0032843]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular response to nitrosative stress [GO:0071500]; nitric oxide catabolic process [GO:0046210]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]		cellular response to nitrosative stress [GO:0071500]; nitric oxide catabolic process [GO:0046210]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	FAD binding [GO:0071949]; fatty acid binding [GO:0005504]; heme binding [GO:0020037]; hydroperoxide reductase activity [GO:0032843]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3vs0b2_d1o4la___1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of cell-cell adhesion [GO:0022407]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein homooligomerization [GO:0032463]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell population proliferation [GO:0042127]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]	ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase activity [GO:0016301]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; SH3/SH2 adaptor activity [GO:0005070]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]
d3vs2b2_d2gsba1__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTPase binding [GO:0051020]; phosphotyrosine residue binding [GO:0001784]; potassium channel inhibitor activity [GO:0019870]; signaling receptor binding [GO:0005102]; blood vessel morphogenesis [GO:0048514]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Ras protein signal transduction [GO:0046580]; regulation of actin filament polymerization [GO:0030833]; regulation of cell shape [GO:0008360]; regulation of RNA metabolic process [GO:0051252]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570]	cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	blood vessel morphogenesis [GO:0048514]; ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Ras protein signal transduction [GO:0046580]; regulation of actin filament polymerization [GO:0030833]; regulation of cell shape [GO:0008360]; regulation of RNA metabolic process [GO:0051252]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; ruffle [GO:0001726]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]	GTPase activator activity [GO:0005096]; GTPase activity [GO:0003924]; GTPase binding [GO:0051020]; phosphotyrosine residue binding [GO:0001784]; potassium channel inhibitor activity [GO:0019870]; signaling receptor binding [GO:0005102]
d3vs6a2_d4ohha1__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]; abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axon guidance [GO:0007411]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to mechanical stimulus [GO:0071260]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet activation [GO:0030168]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]	cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; D1 dopamine receptor binding [GO:0031748]; insulin receptor binding [GO:0005158]; insulin receptor substrate binding [GO:0043560]; non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; peptide hormone receptor binding [GO:0051428]; phospholipase binding [GO:0043274]; phosphoprotein phosphatase activity [GO:0004721]; phosphotyrosine residue binding [GO:0001784]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; SH3/SH2 adaptor activity [GO:0005070]
d3vs7a2_d2crha1__1	Metazoa	Metazoa	Chordata	Chordata	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]; ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cell-cell junction [GO:0005911]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; phosphotyrosine residue binding [GO:0001784]; Rac guanyl-nucleotide exchange factor activity [GO:0030676]; cytokine-mediated signaling pathway [GO:0019221]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of GTPase activity [GO:0043547]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; reactive oxygen species metabolic process [GO:0072593]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cytokine-mediated signaling pathway [GO:0019221]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G protein-coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of GTPase activity [GO:0043547]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of Ras protein signal transduction [GO:0046579]; reactive oxygen species metabolic process [GO:0072593]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; lysosome [GO:0005764]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133]	cell-cell junction [GO:0005911]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]	guanyl-nucleotide exchange factor activity [GO:0005085]; metal ion binding [GO:0046872]; phosphotyrosine residue binding [GO:0001784]; Rac guanyl-nucleotide exchange factor activity [GO:0030676]
d3vsab__d3vc3f___1		Viridiplantae	Crenarchaeota	Streptophyta	cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]; cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]	cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]	cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]
d3vsca__d1pwef___1		Metazoa	Crenarchaeota	Chordata	cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]; gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]	cysteine biosynthetic process from serine [GO:0006535]	gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]		cytoplasm [GO:0005737]	cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]	L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]
d3vscb__d3x44a___1			Crenarchaeota	Actinobacteria	cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]; cysteine biosynthetic process from serine [GO:0006535]	cysteine synthase activity [GO:0004124]; antibiotic biosynthetic process [GO:0017000]; cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]	antibiotic biosynthetic process [GO:0017000]; cysteine biosynthetic process from serine [GO:0006535]			cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]	cysteine synthase activity [GO:0004124]
d3vsda__d3vbec1__1		Viridiplantae	Crenarchaeota	Streptophyta	cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]; cysteine biosynthetic process from serine [GO:0006535]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]; cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]	cysteine biosynthetic process from serine [GO:0006535]	cyanide metabolic process [GO:0019499]; cysteine biosynthetic process from serine [GO:0006535]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	cystathionine beta-synthase activity [GO:0004122]; cysteine synthase activity [GO:0004124]; O-phosphoserine sulfhydrylase activity [GO:0033847]	cysteine synthase activity [GO:0004124]; L-3-cyanoalanine synthase activity [GO:0050017]; pyridoxal phosphate binding [GO:0030170]
d3vsxb__d1u8gb___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3vsyb__d1ocvd___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	steroid metabolic process [GO:0008202]	steroid metabolic process [GO:0008202]			steroid delta-isomerase activity [GO:0004769]	steroid delta-isomerase activity [GO:0004769]
d3vsyb__d2xrxr___1			Proteobacteria	Proteobacteria	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	steroid metabolic process [GO:0008202]	aromatic compound catabolic process [GO:0019439]			steroid delta-isomerase activity [GO:0004769]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d3vtja__d3cp4a___1			Proteobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3vtmb__d4wjgi___1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme binding [GO:0020037]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3vtta__d2vz3a1__1		Fungi		Ascomycota	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]
d3vttb__d3jv6b___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d3vtwa__d2w9na2__1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d3vtwc__d1j8ca___1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; polyubiquitin modification-dependent protein binding [GO:0031593]; autophagosome assembly [GO:0000045]; negative regulation of clathrin-dependent endocytosis [GO:1900186]; negative regulation of G protein-coupled receptor internalization [GO:1904021]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; regulation of autophagosome assembly [GO:2000785]; regulation of macroautophagy [GO:0016241]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	autophagosome assembly [GO:0000045]; negative regulation of clathrin-dependent endocytosis [GO:1900186]; negative regulation of G protein-coupled receptor internalization [GO:1904021]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; regulation of autophagosome assembly [GO:2000785]; regulation of macroautophagy [GO:0016241]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	autophagosome [GO:0005776]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]	polyubiquitin modification-dependent protein binding [GO:0031593]
d3vu3e__d4j5yc___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	cytosol [GO:0005829]; RNA binding [GO:0003723]; pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cellular response to DNA damage stimulus [GO:0006974]; hydrogen peroxide catabolic process [GO:0042744]; hyperosmotic response [GO:0006972]; response to oxidative stress [GO:0006979]	pathogenesis [GO:0009405]; quorum sensing [GO:0009372]; regulation of carbon utilization [GO:0043609]; regulation of RNA stability [GO:0043487]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; regulation of translation, ncRNA-mediated [GO:0045974]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	catalase activity [GO:0004096]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	RNA binding [GO:0003723]
d3vu8a1_d1yida___1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]; methionyl-tRNA aminoacylation [GO:0006431]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]; tryptophanyl-tRNA aminoacylation [GO:0006436]	methionyl-tRNA aminoacylation [GO:0006431]	tryptophanyl-tRNA aminoacylation [GO:0006436]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine-tRNA ligase activity [GO:0004825]; tRNA binding [GO:0000049]	ATP binding [GO:0005524]; tryptophan-tRNA ligase activity [GO:0004830]
d3vuab__d4wjgx___1		Metazoa	Firmicutes	Chordata	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme binding [GO:0020037]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3vuac__d3qznc___1			Firmicutes	Firmicutes	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; heme binding [GO:0020037]	cell wall [GO:0005618]; extracellular region [GO:0005576]; metal ion binding [GO:0046872]			cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	cell wall [GO:0005618]; extracellular region [GO:0005576]	heme binding [GO:0020037]	metal ion binding [GO:0046872]
d3vuca__d1nh0b___1	Metazoa		Chordata		apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cell maturation [GO:0048469]; cellular response to drug [GO:0035690]; drinking behavior [GO:0042756]; hormone-mediated signaling pathway [GO:0009755]; kidney development [GO:0001822]; male gonad development [GO:0008584]; mesonephros development [GO:0001823]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of MAPK cascade [GO:0043408]; renin-angiotensin regulation of aldosterone production [GO:0002018]; response to cAMP [GO:0051591]; response to cGMP [GO:0070305]; response to immobilization stress [GO:0035902]; response to lipopolysaccharide [GO:0032496]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	apical part of cell [GO:0045177]; cytoplasm [GO:0005737]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; insulin-like growth factor receptor binding [GO:0005159]; peptidase activity [GO:0008233]; signaling receptor binding [GO:0005102]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3vune__d5thba___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3vupa__d1c8ya___1	Metazoa		Mollusca	Actinobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity [GO:0033925]
d3vura1_d1fohb3__1	Metazoa	Fungi	Arthropoda	Basidiomycota	transferase activity [GO:0016740]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]; phenol-containing compound catabolic process [GO:0019336]		phenol-containing compound catabolic process [GO:0019336]			transferase activity [GO:0016740]	FAD binding [GO:0071949]; phenol 2-monooxygenase activity [GO:0018662]
d3vura2_d1gsbb1__1	Metazoa	Metazoa	Arthropoda	Chordata	transferase activity [GO:0016740]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]		glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]		cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	transferase activity [GO:0016740]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d3vuwb__d3phxb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3vuwc__d2zcbb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d3vuyb__d3olmd___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ATP-dependent protein binding [GO:0043008]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; ascospore formation [GO:0030437]; modification-dependent protein catabolic process [GO:0019941]; protein deubiquitination [GO:0016579]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	ascospore formation [GO:0030437]; modification-dependent protein catabolic process [GO:0019941]; protein deubiquitination [GO:0016579]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	ATP-dependent protein binding [GO:0043008]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3vv1b__d5oa5a___1	Metazoa	Fungi	Nematoda (roundworms)	Ascomycota	cytoplasm [GO:0005737]; carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]	cytoplasm [GO:0005737]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; galactoside binding [GO:0016936]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d3vv4a__d2o9ac2__1			Cyanobacteria	Proteobacteria	integral component of membrane [GO:0016021]; protein-chromophore linkage [GO:0018298]; signal transduction [GO:0007165]	cytosol [GO:0005829]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; glyoxylate cycle [GO:0006097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]	protein-chromophore linkage [GO:0018298]; signal transduction [GO:0007165]	glyoxylate cycle [GO:0006097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]	integral component of membrane [GO:0016021]	cytosol [GO:0005829]		DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d3vv5a1_d3h6tb1__1		Metazoa	Deinococcus-Thermus	Chordata	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	membrane [GO:0016020]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ligand-gated ion channel activity [GO:0015276]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3vv5b1_d2cexb___1			Deinococcus-Thermus	Proteobacteria	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	outer membrane-bounded periplasmic space [GO:0030288]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]		carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	membrane [GO:0016020]	outer membrane-bounded periplasmic space [GO:0030288]	ligand-gated ion channel activity [GO:0015276]	
d3vvea1_d2ghab___1			Deinococcus-Thermus	Thermotogae	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	proteasome core complex, alpha-subunit complex [GO:0019773]; carbohydrate transmembrane transporter activity [GO:0015144]; endopeptidase activity [GO:0004175]; ubiquitin-dependent protein catabolic process [GO:0006511]		ubiquitin-dependent protein catabolic process [GO:0006511]	membrane [GO:0016020]	proteasome core complex, alpha-subunit complex [GO:0019773]	ligand-gated ion channel activity [GO:0015276]	carbohydrate transmembrane transporter activity [GO:0015144]; endopeptidase activity [GO:0004175]
d3vvea1_d5ng9a1__1		Metazoa	Deinococcus-Thermus	Chordata	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	membrane [GO:0016020]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ligand-gated ion channel activity [GO:0015276]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3vvfa1_d1sw5c___1			Deinococcus-Thermus	Euryarchaeota	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]			membrane [GO:0016020]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	ligand-gated ion channel activity [GO:0015276]	metal ion binding [GO:0046872]; transmembrane transporter activity [GO:0022857]
d3vvfb1_d4u23a___1		Metazoa	Deinococcus-Thermus	Chordata	membrane [GO:0016020]; ligand-gated ion channel activity [GO:0015276]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	membrane [GO:0016020]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	ligand-gated ion channel activity [GO:0015276]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3vwjb__d5d7sl2__1	Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	
d3vwjc1_d2wwmt1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d3vwkc1_d1kprc1__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3vwvb1_d3u6va1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; smooth endoplasmic reticulum [GO:0005790]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; oxidation-reduction process [GO:0055114]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; protein maturation by protein folding [GO:0022417]; reactive oxygen species metabolic process [GO:0072593]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; oxidation-reduction process [GO:0055114]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; protein maturation by protein folding [GO:0022417]; reactive oxygen species metabolic process [GO:0072593]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; smooth endoplasmic reticulum [GO:0005790]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3vwxc1_d1k3yb2__1	Metazoa	Metazoa	Arthropoda	Chordata	glutathione transferase activity [GO:0004364]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione transferase activity [GO:0004364]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3vwxd1_d1qfna___1	Metazoa		Arthropoda	Proteobacteria	glutathione transferase activity [GO:0004364]	cell [GO:0005623]; electron transfer activity [GO:0009055]; nucleotide binding [GO:0000166]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]		cell redox homeostasis [GO:0045454]; deoxyribonucleotide biosynthetic process [GO:0009263]		cell [GO:0005623]	glutathione transferase activity [GO:0004364]	electron transfer activity [GO:0009055]; nucleotide binding [GO:0000166]; protein disulfide oxidoreductase activity [GO:0015035]
d3vx0a1_d4ttgc3__1	Fungi		Ascomycota	Proteobacteria	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate catabolic process [GO:0016052]	lactose catabolic process [GO:0005990]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]	beta-galactosidase complex [GO:0009341]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3vx1a1_d2v3ga___1	Fungi		Ascomycota	Firmicutes	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate catabolic process [GO:0016052]	cellulose catabolic process [GO:0030245]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]		alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	cellulase activity [GO:0008810]
d3vx1a2_d1e43a1__1	Fungi		Ascomycota	Firmicutes	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]	extracellular region [GO:0005576]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d3vx4a__d2p6ra4__1			Firmicutes	Euryarchaeota	integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled bacteriocin transmembrane transporter activity [GO:0043214]; cysteine-type peptidase activity [GO:0008234]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA repair [GO:0006281]		DNA repair [GO:0006281]	integral component of membrane [GO:0016021]		ATPase activity [GO:0016887]; ATPase-coupled bacteriocin transmembrane transporter activity [GO:0043214]; ATP binding [GO:0005524]; cysteine-type peptidase activity [GO:0008234]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]
d3vxqa1_d1uwgl1__1												
d3vxqa1_d4m5yl1__1												
d3vxqa2_d4x4xb___1												
d3vxqe2_d32c2b2__1												
d3vxta2_d2o5yl2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3vxtb1_d4ynyd2__1												
d3vyhb__d2ahjd___1			Actinobacteria	Actinobacteria	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; nitrile hydratase activity [GO:0018822]; transition metal ion binding [GO:0046914]; nitrile catabolic process [GO:0050899]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	nitrile catabolic process [GO:0050899]	nitrogen compound metabolic process [GO:0006807]			indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; nitrile hydratase activity [GO:0018822]; transition metal ion binding [GO:0046914]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d3vyka1_d4kzva1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; carbohydrate derivative binding [GO:0097367]; metal ion binding [GO:0046872]	integral component of membrane [GO:0016021]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; pattern recognition receptor activity [GO:0038187]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway [GO:0038094]; innate immune response [GO:0045087]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cytokine secretion [GO:0050715]; T cell differentiation involved in immune response [GO:0002292]		defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway [GO:0038094]; innate immune response [GO:0045087]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cytokine secretion [GO:0050715]; T cell differentiation involved in immune response [GO:0002292]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; carbohydrate derivative binding [GO:0097367]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; pattern recognition receptor activity [GO:0038187]
d3vz8c__d1q3sa2__1			Proteobacteria	Euryarchaeota	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]; protein folding [GO:0006457]	'de novo' protein folding [GO:0006458]; cell cycle [GO:0007049]; cell division [GO:0051301]; chaperone cofactor-dependent protein refolding [GO:0051085]; protein folding [GO:0006457]; protein refolding [GO:0042026]; response to heat [GO:0009408]; response to radiation [GO:0009314]; virion assembly [GO:0019068]	protein folding [GO:0006457]	cytosol [GO:0005829]; GroEL-GroES complex [GO:1990220]; membrane [GO:0016020]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; unfolded protein binding [GO:0051082]
d3vzja__d4npra1__1		Fungi	Firmicutes	Ascomycota	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulase activity [GO:0008810]; xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			endo-1,4-beta-xylanase activity [GO:0031176]	cellulase activity [GO:0008810]; xyloglucan-specific endo-beta-1,4-glucanase activity [GO:0033946]
d3vzjc__d1bvva___1			Firmicutes	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d3vzjc__d1loa.4__1		Viridiplantae	Firmicutes	Streptophyta	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	mannose binding [GO:0005537]	xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	mannose binding [GO:0005537]
d3vzjd__d1yrzb1__1			Firmicutes	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan 1,4-beta-xylosidase activity [GO:0009044]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d3vzka__d1c5ha___1			Firmicutes	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d3vzka__d3sh4a___1		Metazoa	Firmicutes	Chordata	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; plasma membrane [GO:0005886]; plasma membrane protein complex [GO:0098797]; amyloid-beta binding [GO:0001540]; calcium ion binding [GO:0005509]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; protein C-terminus binding [GO:0008022]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiovascular system development [GO:0072358]; cell differentiation [GO:0030154]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell death [GO:0060548]; receptor-mediated endocytosis [GO:0006898]; retinoid metabolic process [GO:0001523]; tissue development [GO:0009888]	xylan catabolic process [GO:0045493]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; brain development [GO:0007420]; cardiovascular system development [GO:0072358]; cell differentiation [GO:0030154]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; negative regulation of amyloid fibril formation [GO:1905907]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell death [GO:0060548]; receptor-mediated endocytosis [GO:0006898]; retinoid metabolic process [GO:0001523]; tissue development [GO:0009888]		basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi lumen [GO:0005796]; lysosomal lumen [GO:0043202]; plasma membrane [GO:0005886]; plasma membrane protein complex [GO:0098797]	endo-1,4-beta-xylanase activity [GO:0031176]	amyloid-beta binding [GO:0001540]; calcium ion binding [GO:0005509]; extracellular matrix structural constituent conferring compression resistance [GO:0030021]; integrin binding [GO:0005178]; low-density lipoprotein particle receptor binding [GO:0050750]; protein C-terminus binding [GO:0008022]
d3vzlc__d3hd8b___1			Firmicutes	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d3vzma__d2bwcb___1			Firmicutes	Bacteroidetes	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	xylan catabolic process [GO:0045493]	polysaccharide catabolic process [GO:0000272]			endo-1,4-beta-xylanase activity [GO:0031176]	cellulase activity [GO:0008810]
d3vzna__d2vuja___1			Firmicutes		endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]				endo-1,4-beta-xylanase activity [GO:0031176]	
d3vzpb1_d5u8pa___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetoacetyl-CoA reductase activity [GO:0018454]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetoacetyl-CoA reductase activity [GO:0018454]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3vzpd1_d1lrja___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; acetoacetyl-CoA reductase activity [GO:0018454]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]; carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	acetoacetyl-CoA reductase activity [GO:0018454]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]
d3vzqa__d3tfqd1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; acetoacetyl-CoA reductase activity [GO:0018454]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytoplasm [GO:0005737]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	acetoacetyl-CoA reductase activity [GO:0018454]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d3vzrb__d1ipeb___1		Viridiplantae	Proteobacteria	Streptophyta	cytoplasm [GO:0005737]; acetoacetyl-CoA reductase activity [GO:0018454]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	tropinone reductase activity [GO:0050358]; tropane alkaloid biosynthetic process [GO:0009710]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	tropane alkaloid biosynthetic process [GO:0009710]	cytoplasm [GO:0005737]		acetoacetyl-CoA reductase activity [GO:0018454]	tropinone reductase activity [GO:0050358]
d3vzsa__d4qo8b1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; acetoacetyl-CoA reductase activity [GO:0018454]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	acetoacetyl-CoA reductase activity [GO:0018454]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d3vzsb1_d4kwha___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; acetoacetyl-CoA reductase activity [GO:0018454]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetoacetyl-CoA reductase activity [GO:0018454]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3vzsc__d2hk9a2__1			Proteobacteria	Aquificae	cytoplasm [GO:0005737]; acetoacetyl-CoA reductase activity [GO:0018454]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	acetoacetyl-CoA reductase activity [GO:0018454]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d3vzsd1_d1i10b1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; acetoacetyl-CoA reductase activity [GO:0018454]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	acetoacetyl-CoA reductase activity [GO:0018454]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d3vzva__d3daba1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; 5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]
d3vzxa__d5k1ua___1			Firmicutes	Proteobacteria	magnesium ion binding [GO:0000287]; polyprenyltransferase activity [GO:0002094]; glycerophospholipid biosynthetic process [GO:0046474]	cytosol [GO:0005829]; FMN binding [GO:0010181]; riboflavin reductase (NADPH) activity [GO:0042602]	glycerophospholipid biosynthetic process [GO:0046474]			cytosol [GO:0005829]	magnesium ion binding [GO:0000287]; polyprenyltransferase activity [GO:0002094]	FMN binding [GO:0010181]; riboflavin reductase (NADPH) activity [GO:0042602]
d3w06a__d3cn9a___1	Viridiplantae		Streptophyta	Proteobacteria	cytosol [GO:0005829]; nucleus [GO:0005634]; hydrolase activity [GO:0016787]; de-etiolation [GO:0009704]; photomorphogenesis [GO:0009640]; response to karrikin [GO:0080167]	carboxylic ester hydrolase activity [GO:0052689]	de-etiolation [GO:0009704]; photomorphogenesis [GO:0009640]; response to karrikin [GO:0080167]		cytosol [GO:0005829]; nucleus [GO:0005634]		hydrolase activity [GO:0016787]	carboxylic ester hydrolase activity [GO:0052689]
d3w0td__d1bh5b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; pyruvate metabolic process [GO:0006090]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]; carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; pyruvate metabolic process [GO:0006090]; regulation of transcription by RNA polymerase II [GO:0006357]	carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; pyruvate metabolic process [GO:0006090]; regulation of transcription by RNA polymerase II [GO:0006357]	carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; pyruvate metabolic process [GO:0006090]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]	lactoylglutathione lyase activity [GO:0004462]; zinc ion binding [GO:0008270]
d3w15c1_d3o6ga1__1		Metazoa	Proteobacteria	Chordata	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3w1na__d3l66a___1				Proteobacteria	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3w1pa__d3tx9a___1		Fungi		Ascomycota	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]
d3w1qa__d3w01a1__1				Firmicutes	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	magnesium ion binding [GO:0000287]; polyprenyltransferase activity [GO:0002094]; glycerophospholipid biosynthetic process [GO:0046474]	'de novo' UMP biosynthetic process [GO:0044205]	glycerophospholipid biosynthetic process [GO:0046474]	cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	magnesium ion binding [GO:0000287]; polyprenyltransferase activity [GO:0002094]
d3w1qa__d4qaib___1		Fungi		Ascomycota	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3w1ra__d3krza___1				Firmicutes	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3w1ta__d3l5la___1				Proteobacteria	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3w1ub__d3gr8a___1				Firmicutes	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; NADP binding [GO:0050661]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]; response to toxic substance [GO:0009636]	'de novo' UMP biosynthetic process [GO:0044205]	response to toxic substance [GO:0009636]	cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; NADP binding [GO:0050661]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]
d3w1xa__d1jqvb___1				Firmicutes	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d3w23a__d3hf3a___1				Deinococcus-Thermus	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3w25a__d5okbb___1			Firmicutes	Firmicutes	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	6-phospho-beta-galactosidase activity [GO:0033920]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	6-phospho-beta-galactosidase activity [GO:0033920]
d3w26a__d3mmwc___1			Firmicutes	Thermotogae	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	polysaccharide catabolic process [GO:0000272]	cellular glucan metabolic process [GO:0006073]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3w28a__d2gjpa2__1			Firmicutes	Firmicutes	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]; starch catabolic process [GO:0005983]	polysaccharide catabolic process [GO:0000272]	starch catabolic process [GO:0005983]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	calcium ion binding [GO:0005509]; glucan 1,4-alpha-maltohexaosidase activity [GO:0033927]
d3w29a__d3wsua1__1			Firmicutes	Actinobacteria	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]			carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]
d3w2dl1_d3dhja___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3w2dl1_d3to4d1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	extracellular region [GO:0005576]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3w2ea1_d4g6ib2__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]	riboflavin binding [GO:1902444]; riboflavin synthase activity [GO:0004746]; protein homotrimerization [GO:0070207]; riboflavin biosynthetic process [GO:0009231]	cholesterol biosynthetic process [GO:0006695]	protein homotrimerization [GO:0070207]; riboflavin biosynthetic process [GO:0009231]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	riboflavin binding [GO:1902444]; riboflavin synthase activity [GO:0004746]
d3w2ha2_d5vw3a2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cholesterol biosynthetic process [GO:0006695]		endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	chloroplast [GO:0009507]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d3w2ia1_d4fxuc2__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]	riboflavin binding [GO:1902444]; riboflavin synthase activity [GO:0004746]; protein homotrimerization [GO:0070207]; riboflavin biosynthetic process [GO:0009231]	cholesterol biosynthetic process [GO:0006695]	protein homotrimerization [GO:0070207]; riboflavin biosynthetic process [GO:0009231]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]		cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	riboflavin binding [GO:1902444]; riboflavin synthase activity [GO:0004746]
d3w2ia2_d5fa6a3__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	cholesterol biosynthetic process [GO:0006695]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d3w2la__d2du2a___1				Firmicutes	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d3w2lb__d4e2dd___1					cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3w2xa__d3g4tb___1			Euryarchaeota	Euryarchaeota	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	DNA repair [GO:0006281]	DNA repair [GO:0006281]			DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d3w2ya__d4l1ya___1		Metazoa	Euryarchaeota	Arthropoda	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	extracellular space [GO:0005615]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; nitric oxide transport [GO:0030185]; phosphatidylinositol dephosphorylation [GO:0046856]; vasodilation in other organism [GO:0044552]	DNA repair [GO:0006281]	nitric oxide transport [GO:0030185]; phosphatidylinositol dephosphorylation [GO:0046856]; vasodilation in other organism [GO:0044552]		extracellular space [GO:0005615]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3w37a2_d1pama4__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d3w38a3_d1nm9a1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]	extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]		extracellular exosome [GO:0070062]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; metal ion binding [GO:0046872]
d3w39d2_d2igfl2__1	Metazoa	Metazoa	Chordata	Annelida	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]	iron ion binding [GO:0005506]; oxygen carrier activity [GO:0005344]
d3w3bb__d3iwug___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d3w3da2_d5gn6a1__1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]		carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]		ATP binding [GO:0005524]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]
d3w3ea__d4wlya___1	Viridiplantae	Metazoa	Streptophyta	Chordata	chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	chitinase activity [GO:0004568]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3w3eb__d5lina___1	Viridiplantae	Metazoa	Streptophyta	Chordata	chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	chitinase activity [GO:0004568]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3w4ua__d1qpwa___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3w4ue__d1yh9a___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; blood coagulation [GO:0007596]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; neutrophil degranulation [GO:0043312]; nitric oxide transport [GO:0030185]; oxygen transport [GO:0015671]; platelet aggregation [GO:0070527]; positive regulation of cell death [GO:0010942]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; receptor-mediated endocytosis [GO:0006898]; regulation of blood pressure [GO:0008217]; renal absorption [GO:0070293]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; tertiary granule lumen [GO:1904724]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; hemoglobin binding [GO:0030492]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3w53a__d2bfgf2__1			Actinobacteria	Firmicutes	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d3w58a__d4uw3b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]	carbohydrate binding [GO:0030246]
d3w59d__d4uw6a___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	apoptotic process [GO:0006915]; cellular protein metabolic process [GO:0044267]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of viral entry into host cell [GO:0046598]; post-translational protein modification [GO:0043687]; regulation of apoptotic process [GO:0042981]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	apoptotic process [GO:0006915]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	cell [GO:0005623]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; intracellular [GO:0005622]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]	carbohydrate binding [GO:0030246]
d3w5ha2_d2bgia2__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	cholesterol biosynthetic process [GO:0006695]		endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	cytoplasm [GO:0005737]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d3w5ua1_d1qh0a1__1	Viridiplantae		Streptophyta	Cyanobacteria	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane protein complex [GO:0098807]	phycobilisome [GO:0030089]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d3w5ub__d1n62d2__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]		chloroplast thylakoid membrane protein complex [GO:0098807]		electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3w5ue1_d2bmwa1__1	Viridiplantae		Streptophyta	Cyanobacteria	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane protein complex [GO:0098807]	phycobilisome [GO:0030089]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d3w5ue2_d1h42a2__1	Viridiplantae		Streptophyta	Cyanobacteria	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane protein complex [GO:0098807]	phycobilisome [GO:0030089]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d3w5ug1_d4eh1a1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	cell [GO:0005623]; 6,7-dihydropteridine reductase activity [GO:0004155]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular iron ion homeostasis [GO:0006879]; cellular response to nitrosative stress [GO:0071500]; nitric oxide catabolic process [GO:0046210]; response to toxic substance [GO:0009636]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	cellular iron ion homeostasis [GO:0006879]; cellular response to nitrosative stress [GO:0071500]; nitric oxide catabolic process [GO:0046210]; response to toxic substance [GO:0009636]	chloroplast thylakoid membrane protein complex [GO:0098807]	cell [GO:0005623]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	6,7-dihydropteridine reductase activity [GO:0004155]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3w5ug2_d1cnfa2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; FAD binding [GO:0071949]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; nitrate reductase (NADH) activity [GO:0009703]; nitrate assimilation [GO:0042128]; nitric oxide biosynthetic process [GO:0006809]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	nitrate assimilation [GO:0042128]; nitric oxide biosynthetic process [GO:0006809]	chloroplast thylakoid membrane protein complex [GO:0098807]	cytosol [GO:0005829]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	FAD binding [GO:0071949]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; nitrate reductase (NADH) activity [GO:0009703]
d3w5uh__d3p4sn1__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast thylakoid membrane protein complex [GO:0098807]; electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]; anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; photosynthesis [GO:0015979]	anaerobic respiration [GO:0009061]; bacterial-type flagellum assembly [GO:0044780]; bacterial-type flagellum-dependent cell motility [GO:0071973]; fermentation [GO:0006113]; tricarboxylic acid cycle [GO:0006099]	chloroplast thylakoid membrane protein complex [GO:0098807]	cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane fumarate reductase complex [GO:0045284]	electron transfer activity [GO:0009055]; ferredoxin-NADP+ reductase activity [GO:0004324]; NADPH dehydrogenase activity [GO:0003959]; nucleotide binding [GO:0000166]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]	2 iron, 2 sulfur cluster binding [GO:0051537]; 3 iron, 4 sulfur cluster binding [GO:0051538]; 4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; succinate dehydrogenase activity [GO:0000104]
d3w68c1_d1r5la1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; late endosome [GO:0005770]; lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin binding [GO:0019842]; vitamin E binding [GO:0008431]; embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; placenta development [GO:0001890]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]	cell [GO:0005623]; cytosol [GO:0005829]; late endosome [GO:0005770]; lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin E binding [GO:0008431]; embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; lipid metabolic process [GO:0006629]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]	embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; placenta development [GO:0001890]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]	embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; lipid metabolic process [GO:0006629]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; late endosome [GO:0005770]	cell [GO:0005623]; cytosol [GO:0005829]; late endosome [GO:0005770]	lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin binding [GO:0019842]; vitamin E binding [GO:0008431]	lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin E binding [GO:0008431]
d3w68d2_d4tlga2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; late endosome [GO:0005770]; lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin binding [GO:0019842]; vitamin E binding [GO:0008431]; embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; placenta development [GO:0001890]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]	lipid binding [GO:0008289]	embryonic placenta development [GO:0001892]; intermembrane lipid transfer [GO:0120009]; intracellular pH reduction [GO:0051452]; negative regulation of cell death [GO:0060548]; negative regulation of establishment of blood-brain barrier [GO:0090212]; placenta development [GO:0001890]; response to nutrient [GO:0007584]; response to pH [GO:0009268]; response to toxic substance [GO:0009636]; vitamin E metabolic process [GO:0042360]; vitamin transport [GO:0051180]		cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; late endosome [GO:0005770]		lipid transfer activity [GO:0120013]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; vitamin binding [GO:0019842]; vitamin E binding [GO:0008431]	lipid binding [GO:0008289]
d3w69a__d4oase___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; 5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; 5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d3w69b__d3tj2a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; 5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; 5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	amyloid fibril formation [GO:1990000]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac septum morphogenesis [GO:0060411]; cellular response to actinomycin D [GO:0072717]; cellular response to alkaloid [GO:0071312]; cellular response to estrogen stimulus [GO:0071391]; cellular response to gamma radiation [GO:0071480]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to UV-C [GO:0071494]; cellular response to vitamin B1 [GO:0071301]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; establishment of protein localization [GO:0045184]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein processing [GO:0010955]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-lysine modification [GO:0018205]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein localization to nucleus [GO:0034504]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of heart rate [GO:0002027]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to antibiotic [GO:0046677]; response to cocaine [GO:0042220]; response to ether [GO:0045472]; response to formaldehyde [GO:1904404]; response to iron ion [GO:0010039]; response to magnesium ion [GO:0032026]; response to morphine [GO:0043278]; response to steroid hormone [GO:0048545]; response to water-immersion restraint stress [GO:1990785]; transcription factor catabolic process [GO:0036369]; traversing start control point of mitotic cell cycle [GO:0007089]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular septum development [GO:0003281]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; synapse [GO:0045202]	5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]	5S rRNA binding [GO:0008097]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; ligase activity [GO:0016874]; NEDD8 ligase activity [GO:0061663]; p53 binding [GO:0002039]; peroxisome proliferator activated receptor binding [GO:0042975]; protein domain specific binding [GO:0019904]; protein N-terminus binding [GO:0047485]; receptor serine/threonine kinase binding [GO:0033612]; ribonucleoprotein complex binding [GO:0043021]; scaffold protein binding [GO:0097110]; SUMO transferase activity [GO:0019789]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d3w6ha__d5e5uc___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; toxin transport [GO:1901998]	bicarbonate transport [GO:0015701]; interleukin-12-mediated signaling pathway [GO:0035722]; one-carbon metabolic process [GO:0006730]	negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; toxin transport [GO:1901998]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]	arylesterase activity [GO:0004064]; carbonate dehydratase activity [GO:0004089]; hydro-lyase activity [GO:0016836]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]
d3w6ya__d5ebue___1				Firmicutes	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d3w72a__d1jueb___1				Firmicutes	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d3w73a__d1djqa1__1				Proteobacteria	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	4 iron, 4 sulfur cluster binding [GO:0051539]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]; trimethylamine dehydrogenase activity [GO:0050470]
d3w74a__d2h8xa___1				Proteobacteria	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]
d3w76a__d1oyca___1		Fungi		Ascomycota	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; NADPH dehydrogenase activity [GO:0003959]; pentaerythritol trinitrate reductase activity [GO:0018548]; trichloro-p-hydroquinone reductive dehalogenase activity [GO:0052690]
d3w76a__d4e2ba___1					cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3w7ib__d2j6xc___1				Firmicutes	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d3w7lb__d5lnia___1				Proteobacteria	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3w7qb__d5lnja___1				Proteobacteria	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	'de novo' UMP biosynthetic process [GO:0044205]		cytoplasm [GO:0005737]		dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d3w86b__d1jrca___1				Firmicutes	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	'de novo' UMP biosynthetic process [GO:0044205]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d3w8da__d4nbtc___1			Proteobacteria	Tenericutes	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; nucleotide binding [GO:0000166]					3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; nucleotide binding [GO:0000166]
d3w8ea__d3bxxd___1		Viridiplantae	Proteobacteria	Streptophyta	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]; anthocyanin-containing compound biosynthetic process [GO:0009718]		anthocyanin-containing compound biosynthetic process [GO:0009718]			3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]
d3w8sa1_d1oyjd2__1	Metazoa	Viridiplantae	Nematoda (roundworms)	Streptophyta	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]		glutathione metabolic process [GO:0006749]		cytoplasm [GO:0005737]	transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]
d3w95a1_d2bdik___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; secretory granule [GO:0030141]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; DNA replication [GO:0006260]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	amelogenesis [GO:0097186]; biomineral tissue development [GO:0031214]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular region [GO:0005576]; secretory granule [GO:0030141]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3w9bb__d1du4b___1	Fungi	Fungi	Basidiomycota	Ascomycota	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]			triglyceride lipase activity [GO:0004806]	triglyceride lipase activity [GO:0004806]
d3w9bb__d3m81b___1	Fungi		Basidiomycota	Thermotogae	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cytoplasm [GO:0005737]; acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]; cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]	lipid catabolic process [GO:0016042]	cellulose catabolic process [GO:0030245]; cephalosporin C metabolic process [GO:1901266]; polysaccharide metabolic process [GO:0005976]; xylan metabolic process [GO:0045491]		cytoplasm [GO:0005737]	triglyceride lipase activity [GO:0004806]	acetylxylan esterase activity [GO:0046555]; calcium ion binding [GO:0005509]; cephalosporin-C deacetylase activity [GO:0047739]
d3w9bc__d4gi1b___1	Fungi	Fungi	Basidiomycota	Ascomycota	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]	lipid catabolic process [GO:0016042]			triglyceride lipase activity [GO:0004806]	triglyceride lipase activity [GO:0004806]
d3w9bd__d1u8ea2__1	Fungi	Metazoa	Basidiomycota	Chordata	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	lipid catabolic process [GO:0016042]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	triglyceride lipase activity [GO:0004806]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3w9cb__d2wdqb1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]; aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	(+)-camphor catabolic process [GO:0019383]	aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; succinate dehydrogenase complex [GO:0045281]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; succinate dehydrogenase (ubiquinone) activity [GO:0008177]; ubiquinone binding [GO:0048039]
d3w9db1_d1indl1__1												
d3w9dd1_d1l7ih1__1		Metazoa		Chordata								
d3w9tb1_d4lo2a2__1	Metazoa		Echinodermata	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]						carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	
d3w9tc1_d4lo0a1__1	Metazoa		Echinodermata	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]						carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	
d3w9tc2_d4qd2i1__1	Metazoa	Metazoa	Echinodermata	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]; alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]; adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell morphogenesis [GO:0000902]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; intestinal epithelial cell development [GO:0060576]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]		adherens junction organization [GO:0034332]; bicellular tight junction assembly [GO:0070830]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion [GO:0098609]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell-cell junction assembly [GO:0007043]; cell morphogenesis [GO:0000902]; cellular response to amino acid stimulus [GO:0071230]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; cochlea development [GO:0090102]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; epithelial cell morphogenesis [GO:0003382]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of protein processing [GO:0010955]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein metabolic process [GO:0019538]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of gene expression [GO:0010468]; regulation of neuron migration [GO:2001222]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein localization to cell surface [GO:2000008]; regulation of water loss via skin [GO:0033561]; salivary gland cavitation [GO:0060662]; sensory perception of sound [GO:0007605]; synapse assembly [GO:0007416]; trophectodermal cell differentiation [GO:0001829]; uterine epithelium development [GO:0035847]		actin cytoskeleton [GO:0015629]; adherens junction [GO:0005912]; apical junction complex [GO:0043296]; apical part of cell [GO:0045177]; axon [GO:0030424]; axon terminus [GO:0043679]; basolateral plasma membrane [GO:0016323]; catenin complex [GO:0016342]; cell-cell adherens junction [GO:0005913]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell periphery [GO:0071944]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; endosome [GO:0005768]; flotillin complex [GO:0016600]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; lamellipodium [GO:0030027]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; node of Ranvier [GO:0033268]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Schmidt-Lanterman incisure [GO:0043220]; trans-Golgi network [GO:0005802]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	alpha-catenin binding [GO:0045294]; ankyrin binding [GO:0030506]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; cytoskeletal protein binding [GO:0008092]; gamma-catenin binding [GO:0045295]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein phosphatase binding [GO:0019903]
d3w9te1_d1ybib2__1	Metazoa		Echinodermata	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]						carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	
d3w9tf1_d3ah1b1__1	Metazoa		Echinodermata		carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]		extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]
d3w9tg1_d1yf8b2__1	Metazoa	Viridiplantae	Echinodermata	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3w9tg1_d4za3b1__1	Metazoa	Viridiplantae	Echinodermata	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]; defense response [GO:0006952]; negative regulation of translation [GO:0017148]		defense response [GO:0006952]; negative regulation of translation [GO:0017148]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	rRNA N-glycosylase activity [GO:0030598]; toxin activity [GO:0090729]
d3w9va__d3fv1a___1		Metazoa		Chordata	extracellular region [GO:0005576]; phosphate ion transport [GO:0006817]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	phosphate ion transport [GO:0006817]	central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; glutamate receptor signaling pathway [GO:0007215]; modulation of chemical synaptic transmission [GO:0050804]; nervous system development [GO:0007399]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]	extracellular region [GO:0005576]	cell junction [GO:0030054]; integral component of plasma membrane [GO:0005887]; kainate selective glutamate receptor complex [GO:0032983]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]		glutamate receptor activity [GO:0008066]; kainate selective glutamate receptor activity [GO:0015277]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3wa0a1_d3zrfj___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]	ubiquitin protein ligase binding [GO:0031625]
d3wa0b2_d4ny0a2__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]; actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	angiogenesis [GO:0001525]; axon guidance [GO:0007411]; cell motility [GO:0048870]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of cell polarity [GO:0030010]; extracellular matrix organization [GO:0030198]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; growth hormone receptor signaling pathway [GO:0060396]; heart morphogenesis [GO:0003007]; integrin-mediated signaling pathway [GO:0007229]; MAPK cascade [GO:0000165]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; placenta development [GO:0001890]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; regulation of endothelial cell migration [GO:0010594]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	adherens junction [GO:0005912]; apical plasma membrane [GO:0016324]; cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stress fiber [GO:0001725]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]	actin binding [GO:0003779]; ATP binding [GO:0005524]; JUN kinase binding [GO:0008432]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]
d3wa0c1_d1we7a1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type prespliceosome [GO:0071004]; U2-type spliceosomal complex [GO:0005684]; RNA binding [GO:0003723]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	catalytic step 2 spliceosome [GO:0071013]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2 snRNP [GO:0005686]; U2-type precatalytic spliceosome [GO:0071005]; U2-type prespliceosome [GO:0071004]; U2-type spliceosomal complex [GO:0005684]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]	RNA binding [GO:0003723]
d3wa0c1_d5y3bg___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	axon terminus [GO:0043679]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]; actin binding [GO:0003779]; gamma-tubulin binding [GO:0043015]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein domain specific binding [GO:0019904]; canonical Wnt signaling pathway [GO:0060070]; cell proliferation in forebrain [GO:0021846]; cerebellar cortex development [GO:0021695]; cerebral cortex cell migration [GO:0021795]; cerebral cortex radially oriented cell migration [GO:0021799]; forebrain ventricular zone progenitor cell division [GO:0021869]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of axonogenesis [GO:0050772]; positive regulation of JNK cascade [GO:0046330]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microtubule cytoskeleton organization [GO:0070507]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	canonical Wnt signaling pathway [GO:0060070]; cell proliferation in forebrain [GO:0021846]; cerebellar cortex development [GO:0021695]; cerebral cortex cell migration [GO:0021795]; cerebral cortex radially oriented cell migration [GO:0021799]; forebrain ventricular zone progenitor cell division [GO:0021869]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of axonogenesis [GO:0050772]; positive regulation of JNK cascade [GO:0046330]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microtubule cytoskeleton organization [GO:0070507]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	axon terminus [GO:0043679]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; neuronal cell body [GO:0043025]; protein-containing complex [GO:0032991]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]	actin binding [GO:0003779]; gamma-tubulin binding [GO:0043015]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein domain specific binding [GO:0019904]
d3wa0c2_d2d10c1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]; actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	apical protein localization [GO:0045176]; barbed-end actin filament capping [GO:0051016]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; cell-cell adherens junction [GO:0005913]; cell periphery [GO:0071944]; cell tip [GO:0051286]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; microvillus [GO:0005902]; midbody [GO:0030496]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; stereocilium [GO:0032420]; T-tubule [GO:0030315]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]	actin binding [GO:0003779]; ATPase binding [GO:0051117]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]
d3wa0c3_d1zc4d___1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cell surface [GO:0009986]; cleavage furrow [GO:0032154]; cytoplasmic vesicle membrane [GO:0030659]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; ATPase binding [GO:0051117]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; myosin binding [GO:0017022]; ubiquitin protein ligase binding [GO:0031625]; actin cytoskeleton reorganization [GO:0031532]; cell cycle [GO:0007049]; cell division [GO:0051301]; chemotaxis [GO:0006935]; exocytosis [GO:0006887]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane organization [GO:0061024]; membrane raft localization [GO:0051665]; neural tube closure [GO:0001843]; positive regulation of filopodium assembly [GO:0051491]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; signal transduction [GO:0007165]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin cytoskeleton reorganization [GO:0031532]; cell cycle [GO:0007049]; cell division [GO:0051301]; chemotaxis [GO:0006935]; exocytosis [GO:0006887]; interleukin-12-mediated signaling pathway [GO:0035722]; membrane organization [GO:0061024]; membrane raft localization [GO:0051665]; neural tube closure [GO:0001843]; positive regulation of filopodium assembly [GO:0051491]; Ras protein signal transduction [GO:0007265]; regulation of exocytosis [GO:0017157]; signal transduction [GO:0007165]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	cell surface [GO:0009986]; cleavage furrow [GO:0032154]; cytoplasmic vesicle membrane [GO:0030659]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]	ATPase binding [GO:0051117]; Edg-2 lysophosphatidic acid receptor binding [GO:0031755]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; myosin binding [GO:0017022]; ubiquitin protein ligase binding [GO:0031625]
d3wa0e2_d4zrib2__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; actin binding [GO:0003779]; actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium membrane [GO:0031527]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]	actin binding [GO:0003779]
d3wa0f1_d5jg6b1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3wa0f3_d1mkea1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin cortical patch [GO:0030479]; actin filament [GO:0005884]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; postsynapse [GO:0098794]; actin filament binding [GO:0051015]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]; actin cortical patch assembly [GO:0000147]; actin cortical patch localization [GO:0051666]; actin filament polymerization [GO:0030041]; actin filament-based movement [GO:0030048]; cell cycle [GO:0007049]; cell division [GO:0051301]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; membrane invagination [GO:0010324]; plasma membrane tubulation [GO:0097320]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynaptic actin cytoskeleton organization [GO:0098974]; vesicle budding from membrane [GO:0006900]; vesicle organization [GO:0016050]; vesicle transport along actin filament [GO:0030050]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	actin cortical patch assembly [GO:0000147]; actin cortical patch localization [GO:0051666]; actin filament-based movement [GO:0030048]; actin filament polymerization [GO:0030041]; cell cycle [GO:0007049]; cell division [GO:0051301]; dendritic spine morphogenesis [GO:0060997]; endocytosis [GO:0006897]; membrane invagination [GO:0010324]; plasma membrane tubulation [GO:0097320]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynaptic actin cytoskeleton organization [GO:0098974]; vesicle budding from membrane [GO:0006900]; vesicle organization [GO:0016050]; vesicle transport along actin filament [GO:0030050]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	actin cortical patch [GO:0030479]; actin filament [GO:0005884]; cell [GO:0005623]; cell leading edge [GO:0031252]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; nucleus [GO:0005634]; postsynapse [GO:0098794]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]	actin filament binding [GO:0051015]; cytoskeletal protein binding [GO:0008092]; identical protein binding [GO:0042802]
d3wa9c__d2hioc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3wa9d__d3azfc___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3wa9h__d3mvdb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleoplasm [GO:0005654]; nucleosome [GO:0000786]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3waea__d2r6ge___1			Deinococcus-Thermus	Proteobacteria	metal ion binding [GO:0046872]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3waeb__d4h8jc___1		Metazoa	Deinococcus-Thermus	Chordata	metal ion binding [GO:0046872]	AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]	metal ion binding [GO:0046872]	AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3wala__d5xaca1__1	Metazoa	Metazoa	Chordata	Chordata	autolysosome [GO:0044754]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; microtubule [GO:0005874]; organelle membrane [GO:0031090]; synapse [GO:0045202]; microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; phospholipid binding [GO:0005543]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to amino acid starvation [GO:0034198]; cellular response to copper ion [GO:0071280]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	autolysosome [GO:0044754]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; microtubule [GO:0005874]; organelle membrane [GO:0031090]; synapse [GO:0045202]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	microtubule binding [GO:0008017]; phosphatidylethanolamine binding [GO:0008429]; phospholipid binding [GO:0005543]; ubiquitin protein ligase binding [GO:0031625]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d3waod__d1kjta___1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]; beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein transport [GO:0015031]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; protein transport [GO:0015031]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	actin cytoskeleton [GO:0015629]; autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cell body [GO:0044297]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; lysosome [GO:0005764]; microtubule [GO:0005874]; microtubule associated complex [GO:0005875]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; smooth endoplasmic reticulum [GO:0005790]; sperm midpiece [GO:0097225]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]	beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]
d3wbea__d2guya2__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	extracellular region [GO:0005576]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]	extracellular region [GO:0005576]	cell septum [GO:0030428]; cell wall-bounded periplasmic space [GO:0030287]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; hyphal septin band [GO:0032163]; spitzenkorper [GO:0031521]	beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; hydrolase activity, acting on glycosyl bonds [GO:0016798]; scopolin beta-glucosidase activity [GO:0102483]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]
d3wbga__d3wjcb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	cytosol [GO:0005829]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]	
d3wbgb__d2g7ba___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d3wbgd__d3wjfa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]; cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]; cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	cytosol [GO:0005829]	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; intracellular lipid transport [GO:0032365]; long-chain fatty acid transport [GO:0015909]; negative regulation of cell population proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of long-chain fatty acid import into cell [GO:0140214]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; regulation of phosphatidylcholine biosynthetic process [GO:2001245]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; sarcoplasm [GO:0016528]	cytosol [GO:0005829]	cytoskeletal protein binding [GO:0008092]; icosatetraenoic acid binding [GO:0050543]; long-chain fatty acid binding [GO:0036041]; long-chain fatty acid transporter activity [GO:0005324]; oleic acid binding [GO:0070538]	
d3wbmd__d2h9ua___1			Crenarchaeota	Crenarchaeota	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]; chromosome condensation [GO:0030261]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	chromosome condensation [GO:0030261]		chromosome [GO:0005694]; cytoplasm [GO:0005737]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]	double-stranded DNA binding [GO:0003690]; RNA binding [GO:0003723]
d3wc3a1_d1h13a___1	Metazoa		Annelida	Proteobacteria	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]			cellulase activity [GO:0008810]; metal ion binding [GO:0046872]	endo-1,4-beta-xylanase activity [GO:0031176]
d3wc4a__d3frob1__1	Viridiplantae		Streptophyta	Euryarchaeota	nucleotide binding [GO:0000166]; transferase activity, transferring hexosyl groups [GO:0016758]	glycogen (starch) synthase activity [GO:0004373]; nucleotide binding [GO:0000166]					nucleotide binding [GO:0000166]; transferase activity, transferring hexosyl groups [GO:0016758]	glycogen (starch) synthase activity [GO:0004373]; nucleotide binding [GO:0000166]
d3wc9a__d1rqia1__1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cytosol [GO:0005829]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	cytosol [GO:0005829]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]
d3wcab__d5djpf___1		Metazoa		Chordata	integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]; ergosterol biosynthetic process [GO:0006696]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	ergosterol biosynthetic process [GO:0006696]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3wcbc__d5imic___1		Fungi		Ascomycota	integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]; ergosterol biosynthetic process [GO:0006696]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]	ergosterol biosynthetic process [GO:0006696]		integral component of membrane [GO:0016021]		farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]
d3wccc__d1ubya___1		Metazoa		Chordata	integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]; ergosterol biosynthetic process [GO:0006696]	cytoplasm [GO:0005737]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	ergosterol biosynthetic process [GO:0006696]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]
d3wccd__d3wclf___1		Metazoa		Chordata	integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]; ergosterol biosynthetic process [GO:0006696]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	ergosterol biosynthetic process [GO:0006696]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d3wcdd__d1kizb___1	Metazoa	Fungi	Chordata	Ascomycota	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	sesquiterpenoid biosynthetic process [GO:0016106]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]		farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]
d3wcde__d5imna___1	Metazoa	Fungi	Chordata	Ascomycota	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]		farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]
d3wcea__d5imnb___1		Fungi		Ascomycota	integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]; ergosterol biosynthetic process [GO:0006696]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]	ergosterol biosynthetic process [GO:0006696]		integral component of membrane [GO:0016021]		farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]	aristolochene synthase activity [GO:0045483]; metal ion binding [GO:0046872]
d3wcec__d3n5hf___1		Metazoa		Chordata	integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]; ergosterol biosynthetic process [GO:0006696]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	ergosterol biosynthetic process [GO:0006696]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3wcga__d1rqjb___1				Proteobacteria	integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]; ergosterol biosynthetic process [GO:0006696]	cytosol [GO:0005829]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	ergosterol biosynthetic process [GO:0006696]	farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	integral component of membrane [GO:0016021]	cytosol [GO:0005829]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]
d3wcgb__d3wcfb___1		Metazoa		Chordata	integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]; ergosterol biosynthetic process [GO:0006696]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	ergosterol biosynthetic process [GO:0006696]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d3wcia__d3vj8a___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d3wcie__d3n1wf___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; regulation of cholesterol biosynthetic process [GO:0045540]; viral process [GO:0016032]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	dimethylallyltranstransferase activity [GO:0004161]; geranyltranstransferase activity [GO:0004337]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d3wcif__d3oacd1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]		cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]		farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	
d3wcjf__d3vjce___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d3wclc__d1wl2a___1	Metazoa		Chordata	Thermotogae	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	transferase activity [GO:0016740]; isoprenoid biosynthetic process [GO:0008299]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	isoprenoid biosynthetic process [GO:0008299]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]		farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	transferase activity [GO:0016740]
d3wcpc__d1hgbb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcpc__d2zs1d___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcqa__d1n5wd2__1			Rhodophyta	Proteobacteria	chloroplast [GO:0009507]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]			chloroplast [GO:0009507]		2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]
d3wctc__d1j7wc___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wctg__d3bcqd___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcth__d3wfxa1__1	Metazoa		Annelida	Verrucomicrobia	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]		response to nitrosative stress [GO:0051409]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcua__d5azqa___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcuc__d3a5ga___1	Metazoa	Metazoa	Annelida	Arthropoda	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcud__d1mnja___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcud__d3s1ib___1	Metazoa		Annelida	Verrucomicrobia	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcug__d5jnza___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcva__d1fsxc___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcvc__d3aq8a___1	Metazoa		Annelida	Ciliophora	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcvd__d3wctb___1	Metazoa	Metazoa	Annelida	Annelida	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcvg__d2zs0d___1	Metazoa	Metazoa	Annelida	Annelida	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcvh__d1y7zc___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcwb__d3pi8d___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcwb__d3wcva___1	Metazoa	Metazoa	Annelida	Annelida	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcwd__d3pi1a___1	Metazoa	Metazoa	Annelida	Mollusca	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	cytoplasm [GO:0005737]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]			extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcwe__d3d4xb___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]		cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; hemoglobin alpha binding [GO:0031721]; metal ion binding [GO:0046872]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcwh__d1y0tb___1	Metazoa	Metazoa	Annelida	Chordata	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wcwh__d4xxia___1	Metazoa		Annelida	Cyanobacteria	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	phycobilisome [GO:0030089]; lyase activity [GO:0016829]; oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]		oxidation-reduction process [GO:0055114]; photosynthesis [GO:0015979]; protein-chromophore linkage [GO:0018298]	extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]	phycobilisome [GO:0030089]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	lyase activity [GO:0016829]
d3wcza__d3wbxb___1	Metazoa		Arthropoda	Proteobacteria	oxidoreductase activity [GO:0016491]; steroid metabolic process [GO:0008202]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	steroid metabolic process [GO:0008202]				oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3wcza__d4yvxb___1	Metazoa	Metazoa	Arthropoda	Chordata	oxidoreductase activity [GO:0016491]; steroid metabolic process [GO:0008202]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]; 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; prostaglandin-F synthase activity [GO:0047017]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]; cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]	steroid metabolic process [GO:0008202]	cellular response to cadmium ion [GO:0071276]; cellular response to calcium ion [GO:0071277]; cellular response to corticosteroid stimulus [GO:0071384]; cellular response to jasmonic acid stimulus [GO:0071395]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to prostaglandin stimulus [GO:0071379]; cellular response to reactive oxygen species [GO:0034614]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; daunorubicin metabolic process [GO:0044597]; doxorubicin metabolic process [GO:0044598]; farnesol catabolic process [GO:0016488]; G protein-coupled receptor signaling pathway [GO:0007186]; keratinocyte differentiation [GO:0030216]; macromolecule metabolic process [GO:0043170]; male gonad development [GO:0008584]; negative regulation of retinoic acid biosynthetic process [GO:1900053]; oxidation-reduction process [GO:0055114]; positive regulation of cell death [GO:0010942]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; progesterone metabolic process [GO:0042448]; prostaglandin metabolic process [GO:0006693]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of testosterone biosynthetic process [GO:2000224]; renal absorption [GO:0070293]; response to nutrient [GO:0007584]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; nucleus [GO:0005634]	oxidoreductase activity [GO:0016491]	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity [GO:0047020]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; alditol:NADP+ 1-oxidoreductase activity [GO:0004032]; aldo-keto reductase (NADP) activity [GO:0004033]; androsterone dehydrogenase activity [GO:0047023]; bile acid binding [GO:0032052]; delta4-3-oxosteroid 5beta-reductase activity [GO:0047787]; dihydrotestosterone 17-beta-dehydrogenase activity [GO:0035410]; geranylgeranyl reductase activity [GO:0045550]; indanol dehydrogenase activity [GO:0047718]; ketoreductase activity [GO:0045703]; ketosteroid monooxygenase activity [GO:0047086]; NADP-retinol dehydrogenase activity [GO:0052650]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655]; phenanthrene 9,10-monooxygenase activity [GO:0018636]; prostaglandin D2 11-ketoreductase activity [GO:0036131]; prostaglandin-F synthase activity [GO:0047017]; prostaglandin H2 endoperoxidase reductase activity [GO:0036130]; retinal dehydrogenase activity [GO:0001758]; retinol dehydrogenase activity [GO:0004745]; steroid dehydrogenase activity [GO:0016229]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [GO:0047115]
d3wd5a__d3it8c___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]
d3wd5l1_d1l0xa2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	integral component of membrane [GO:0016021]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]		cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	integral component of membrane [GO:0016021]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]	
d3wd5l1_d3ardd2__1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; astrocyte activation [GO:0048143]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cognition [GO:0050890]; cortical actin cytoskeleton organization [GO:0030866]; cytokine-mediated signaling pathway [GO:0019221]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; endothelial cell apoptotic process [GO:0072577]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; microglial cell activation [GO:0001774]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of amyloid-beta clearance [GO:1900222]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neurogenesis [GO:0050768]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chemokine secretion [GO:0090197]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of fractalkine biosynthetic process [GO:0050754]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitrogen compound metabolic process [GO:0051173]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of synaptic transmission [GO:0050806]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of endothelial cell apoptotic process [GO:2000351]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of fat cell differentiation [GO:0045598]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of synapse organization [GO:0050807]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	cytokine activity [GO:0005125]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; transcription regulatory region DNA binding [GO:0044212]; tumor necrosis factor receptor binding [GO:0005164]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3wd6a2_d1lbkb1__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	glutathione transferase activity [GO:0004364]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3wd6b1_d2diza1__1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; isomerase activity [GO:0016853]; apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]		apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	cytoplasm [GO:0005737]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]	glutathione transferase activity [GO:0004364]	isomerase activity [GO:0016853]
d3wd6b1_d4fh8e___1	Metazoa	Metazoa	Arthropoda	Nematoda (roundworms)	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]	cell [GO:0005623]	glutathione transferase activity [GO:0004364]	peroxiredoxin activity [GO:0051920]
d3wd6c1_d3sbce___1	Metazoa	Fungi	Arthropoda	Ascomycota	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]; identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]; cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]		cell redox homeostasis [GO:0045454]; cellular response to heat [GO:0034605]; cellular response to hydroperoxide [GO:0071447]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein folding [GO:0061077]; DNA damage checkpoint [GO:0000077]; DNA protection [GO:0042262]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of cell aging [GO:0090344]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; protein folding [GO:0006457]; protein polymerization [GO:0051258]; protein stabilization [GO:0050821]; regulation of gluconeogenesis [GO:0006111]; replicative cell aging [GO:0001302]; response to hydroperoxide [GO:0033194]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; polysome [GO:0005844]	glutathione transferase activity [GO:0004364]	identical protein binding [GO:0042802]; kinase regulator activity [GO:0019207]; peroxiredoxin activity [GO:0051920]; ribosome binding [GO:0043022]; thioredoxin peroxidase activity [GO:0008379]; unfolded protein binding [GO:0051082]
d3wd6c1_d4xtsb___1	Metazoa		Arthropoda	Proteobacteria	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]		cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]	glutathione transferase activity [GO:0004364]	thioredoxin peroxidase activity [GO:0008379]
d3wd6d1_d2z9si___1	Metazoa	Metazoa	Arthropoda	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]; heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]		cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; removal of superoxide radicals [GO:0019430]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; nuclear euchromatin [GO:0005719]; nucleolus [GO:0005730]; peroxisomal matrix [GO:0005782]	glutathione transferase activity [GO:0004364]	heme binding [GO:0020037]; peroxiredoxin activity [GO:0051920]; protein homodimerization activity [GO:0042803]; thioredoxin peroxidase activity [GO:0008379]
d3wd6d2_d4kh7b2__1	Metazoa		Arthropoda	Proteobacteria	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]			cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d3wd7b2_d4jb6a2__1	Viridiplantae		Streptophyta	Proteobacteria	acridone synthase activity [GO:0050635]; biosynthetic process [GO:0009058]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]			acridone synthase activity [GO:0050635]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d3wd8a1_d1dm3a2__1	Viridiplantae		Streptophyta	Proteobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	biosynthetic process [GO:0009058]	poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d3wd8a2_d1fj8c2__1	Viridiplantae		Streptophyta	Proteobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d3wd8b2_d1oxhb2__1	Viridiplantae		Streptophyta	Firmicutes	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]			transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d3wd8d1_d2x3ea2__1	Viridiplantae		Streptophyta	Proteobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d3wdfa__d4lylk1__1			Firmicutes		cytoplasm [GO:0005737]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]		base-excision repair [GO:0006284]		cytoplasm [GO:0005737]		uracil DNA N-glycosylase activity [GO:0004844]	
d3wdga__d2euga___1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]		base-excision repair, AP site formation via deaminated base removal [GO:0097510]		mitochondrion [GO:0005739]; nucleus [GO:0005634]	metal ion binding [GO:0046872]	uracil DNA N-glycosylase activity [GO:0004844]
d3wdpp1_d1qoxi___1			Euryarchaeota	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3wdpq1_d2bfgb2__1			Euryarchaeota	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	xylan 1,4-beta-xylosidase activity [GO:0009044]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	xylan 1,4-beta-xylosidase activity [GO:0009044]
d3wdpr1_d1isza2__1			Euryarchaeota	Actinobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	endo-1,4-beta-xylanase activity [GO:0031176]
d3we6b2_d4qrra2__1	Metazoa	Metazoa	Chordata	Chordata	metal ion binding [GO:0046872]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3weab__d1imhc1__1	Metazoa	Metazoa	Arthropoda	Chordata		cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cytokine production [GO:0001816]; excretion [GO:0007588]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; response to osmotic stress [GO:0006970]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]		calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cytokine production [GO:0001816]; excretion [GO:0007588]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; response to osmotic stress [GO:0006970]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]		cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]		chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d3weba__d1svcp1__1	Metazoa	Metazoa	Arthropoda	Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]		apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; neutrophil degranulation [GO:0043312]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription by RNA polymerase II [GO:0006366]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; I-kappaB/NF-kappaB complex [GO:0033256]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; specific granule lumen [GO:0035580]		actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d3weca__d2p85f___1		Metazoa	Actinobacteria	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d3wefc__d3wcdd___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d3wega__d1v4ia___1	Metazoa		Chordata	Thermotogae	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	transferase activity [GO:0016740]; isoprenoid biosynthetic process [GO:0008299]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	isoprenoid biosynthetic process [GO:0008299]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]		farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]	transferase activity [GO:0016740]
d3wena2_d3tv8b1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d3wena3_d2zx9a2__1	Viridiplantae		Streptophyta	Thermotogae	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]	lysosome [GO:0005764]; alpha-L-fucosidase activity [GO:0004560]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]		fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]		lysosome [GO:0005764]	carbohydrate binding [GO:0030246]; maltose alpha-glucosidase activity [GO:0032450]	alpha-L-fucosidase activity [GO:0004560]
d3wexa2_d5jxef2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		
d3wexa2_d5k8am1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]			
d3wexc2_d5f9wl1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	viral envelope [GO:0019031]; virion membrane [GO:0055036]		
d3wexe1_d5d5mc1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3wexe2_d1s78e2__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]
d3wexe2_d6bitl1__1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]	integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]		cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]
d3wexg2_d4gkza2__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		adaptive immune response [GO:0002250]; antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [GO:0002504]		integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]			
d3wfbl1_d3b2ur2__1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]; aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d3wfbl2_d4xcnk1__1			Proteobacteria		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]; aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]		aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]		cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]	
d3wfcl1_d4j1uc1__1			Proteobacteria		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]; aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]		aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]		cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]	
d3wfcl1_d5ovwk___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]; aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; cobalamin binding [GO:0031419]; cobalamin transport [GO:0015889]	aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	cobalamin transport [GO:0015889]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]	cobalamin binding [GO:0031419]
d3wfdl1_d2h2pd1__1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]; aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]		aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]		cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]	
d3wfdl2_d4lqfl2__1			Proteobacteria		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]; aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]	aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	integral component of membrane [GO:0016021]	cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]	metal ion binding [GO:0046872]
d3wfel1_d1ic7h___1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]; aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3wfel2_d4gkza1__1			Proteobacteria		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]; aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]		aerobic respiration [GO:0009060]; denitrification pathway [GO:0019333]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]		cytochrome-c oxidase activity [GO:0004129]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide reductase activity [GO:0016966]	
d3wffa__d5ixkb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; receptor complex [GO:0043235]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]; adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	positive regulation of NIK/NF-kappaB signaling [GO:1901224]; signal transduction [GO:0007165]; transcription initiation from RNA polymerase II promoter [GO:0006367]	adipose tissue development [GO:0060612]; cellular response to sterol [GO:0036315]; circadian regulation of gene expression [GO:0032922]; cytokine-mediated signaling pathway [GO:0019221]; lymph node development [GO:0048535]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Peyer's patch development [GO:0048541]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fat cell differentiation [GO:0045598]; regulation of glucose metabolic process [GO:0010906]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; T-helper cell differentiation [GO:0042093]; transcription initiation from RNA polymerase II promoter [GO:0006367]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; receptor complex [GO:0043235]	nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; sequence-specific DNA binding [GO:0043565]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; ligand-activated transcription factor activity [GO:0098531]; nuclear receptor activity [GO:0004879]; oxysterol binding [GO:0008142]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; steroid hormone receptor activity [GO:0003707]; transcription coactivator binding [GO:0001223]; zinc ion binding [GO:0008270]
d3wfla__d1fhla___1	Fungi	Fungi	Ascomycota	Ascomycota	mannan endo-1,4-beta-mannosidase activity [GO:0016985]; carbohydrate metabolic process [GO:0005975]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; metabolic process [GO:0008152]	carbohydrate metabolic process [GO:0005975]	metabolic process [GO:0008152]			mannan endo-1,4-beta-mannosidase activity [GO:0016985]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]
d3wg3a1_d1fayc___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]				deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3wg7b2_d2j55b___1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3wgda1_d4xtsi___1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; isomerase activity [GO:0016853]; apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]	cell [GO:0005623]; cytosol [GO:0005829]	isomerase activity [GO:0016853]	thioredoxin peroxidase activity [GO:0008379]
d3wgdh1_d4mh3f___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]; isomerase activity [GO:0016853]; apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; negative regulation of apoptotic process [GO:0043066]; neutrophil degranulation [GO:0043312]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	azurophil granule lumen [GO:0035578]; cell [GO:0005623]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; lysosomal lumen [GO:0043202]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	isomerase activity [GO:0016853]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d3wgka1_d5h74b1__1		Metazoa	Firmicutes	Chordata	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d3wgkb2_d4i55c2__1		Metazoa	Firmicutes	Chordata	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; neuron migration [GO:0001764]; positive regulation of axon guidance [GO:1902669]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein heterodimerization activity [GO:0046982]; structural constituent of cytoskeleton [GO:0005200]
d3wgma2_d4x1ib2__1		Metazoa	Firmicutes	Chordata	cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]; tubulin binding [GO:0015631]; microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]	microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	cell division site [GO:0032153]; cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]	tubulin binding [GO:0015631]
d3wgwa1_d4n96a3__1	Metazoa		Chordata	Proteobacteria	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3wgwb1_d1jqjb2__1	Metazoa		Chordata	Proteobacteria	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]; base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	base-excision repair, gap-filling [GO:0006287]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to UV [GO:0034644]; cellular response to xenobiotic stimulus [GO:0071466]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; epithelial cell differentiation [GO:0030855]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; estrous cycle [GO:0044849]; heart development [GO:0007507]; leading strand elongation [GO:0006272]; liver regeneration [GO:0097421]; mismatch repair [GO:0006298]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of deoxyribonuclease activity [GO:0032077]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; protein ubiquitination [GO:0016567]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; replication fork processing [GO:0031297]; response to cadmium ion [GO:0046686]; response to dexamethasone [GO:0071548]; response to estradiol [GO:0032355]; response to L-glutamate [GO:1902065]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	centrosome [GO:0005813]; chromatin [GO:0000785]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; extracellular exosome [GO:0070062]; nuclear body [GO:0016604]; nuclear chromosome, telomeric region [GO:0000784]; nuclear lamina [GO:0005652]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCNA complex [GO:0043626]; PCNA-p21 complex [GO:0070557]; replication fork [GO:0005657]; replisome [GO:0030894]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; dinucleotide insertion or deletion binding [GO:0032139]; DNA polymerase binding [GO:0070182]; DNA polymerase processivity factor activity [GO:0030337]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; MutLalpha complex binding [GO:0032405]; purine-specific mismatch base pair DNA N-glycosylase activity [GO:0000701]; receptor tyrosine kinase binding [GO:0030971]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d3wh0a2_d4j4nb1__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]; cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein dimerization activity [GO:0046983]; chaperone-mediated protein folding [GO:0061077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of type I interferon production [GO:0032480]; neuron differentiation [GO:0030182]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cytokinesis [GO:0032465]; regulation of gene expression [GO:0010468]; regulation of mitotic nuclear division [GO:0007088]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to hypoxia [GO:0001666]; synapse organization [GO:0050808]	chaperone-mediated protein folding [GO:0061077]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; midbody [GO:0030496]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	beta-catenin binding [GO:0008013]; cis-trans isomerase activity [GO:0016859]; GTPase activating protein binding [GO:0032794]; mitogen-activated protein kinase kinase binding [GO:0031434]; motor activity [GO:0003774]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; phosphoserine residue binding [GO:0050815]; phosphothreonine residue binding [GO:0050816]; tau protein binding [GO:0048156]	FK506 binding [GO:0005528]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; protein dimerization activity [GO:0046983]
d3whme__d5chra___1	Metazoa	Metazoa	Chordata	Annelida	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]	bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; peroxidase activity [GO:0004601]
d3whua__d2rfza___1	Metazoa	Fungi	Chordata	Ascomycota	endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; calcium ion binding [GO:0005509]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]	cellulose catabolic process [GO:0030245]	endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]		calcium ion binding [GO:0005509]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3wi2b1_d2oura1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]
d3wi7b__d4dmfd___1			Proteobacteria	Proteobacteria	haloalkane dehalogenase activity [GO:0018786]	hydrolase activity [GO:0016787]					haloalkane dehalogenase activity [GO:0018786]	hydrolase activity [GO:0016787]
d3wi8a__d1y5fd___1	Metazoa	Metazoa	Chordata	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		bicarbonate transport [GO:0015701]; cellular oxidant detoxification [GO:0098869]; hydrogen peroxide catabolic process [GO:0042744]; oxygen transport [GO:0015671]; positive regulation of cell death [GO:0010942]; receptor-mediated endocytosis [GO:0006898]; response to hydrogen peroxide [GO:0042542]		blood microparticle [GO:0072562]; cytosol [GO:0005829]; cytosolic small ribosomal subunit [GO:0022627]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; haptoglobin-hemoglobin complex [GO:0031838]; hemoglobin complex [GO:0005833]; membrane [GO:0016020]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; organic acid binding [GO:0043177]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3wibb__d2qxue___1			Proteobacteria	Firmicutes	haloalkane dehalogenase activity [GO:0018786]	extracellular region [GO:0005576]; lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]		lipid catabolic process [GO:0016042]		extracellular region [GO:0005576]	haloalkane dehalogenase activity [GO:0018786]	lipase activity [GO:0016298]; triglyceride lipase activity [GO:0004806]
d3wifb2_d1rzgb1__1												
d3wihl2_d2q76a1__1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	axon guidance receptor activity [GO:0008046]; identical protein binding [GO:0042802]; LRR domain binding [GO:0030275]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3wiil2_d4rqql1__1												
d3wiil2_d5tfsl2__1												
d3wiim1_d4d0cb___1		Metazoa		Chordata		cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]		amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]		cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]		protein homodimerization activity [GO:0042803]
d3wiim2_d2rika3__1		Metazoa		Chordata		telethonin binding [GO:0031433]						telethonin binding [GO:0031433]
d3wj1a__d4i3fa1__1			Crenarchaeota	Proteobacteria	hydrolase activity [GO:0016787]	hydrolase activity [GO:0016787]					hydrolase activity [GO:0016787]	hydrolase activity [GO:0016787]
d3wj7c__d4wlob1__1		Metazoa	Proteobacteria	Chordata	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d3wjda__d4orxa___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]		cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	cytosol [GO:0005829]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]		fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d3wjea__d3wjca___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytosol [GO:0005829]	cytosol [GO:0005829]			cytosol [GO:0005829]	cytosol [GO:0005829]		
d3wjja2_d3lmjl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3wjjb2_d1jtpb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]; glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytoplasm [GO:0005737]; extracellular space [GO:0005615]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	glycosaminoglycan binding [GO:0005539]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3wjjc1_d4nqdb___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3wjjc2_d4cl7c___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]
d3wjla2_d1kfai1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3wjlc2_d2avga1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	A band [GO:0031672]; C zone [GO:0014705]; cardiac myofibril [GO:0097512]; cytosol [GO:0005829]; sarcomere [GO:0030017]; striated muscle myosin thick filament [GO:0005863]; actin binding [GO:0003779]; ATPase activator activity [GO:0001671]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; myosin heavy chain binding [GO:0032036]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	A band [GO:0031672]; cardiac myofibril [GO:0097512]; cytosol [GO:0005829]; C zone [GO:0014705]; sarcomere [GO:0030017]; striated muscle myosin thick filament [GO:0005863]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin binding [GO:0003779]; ATPase activator activity [GO:0001671]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; myosin binding [GO:0017022]; myosin heavy chain binding [GO:0032036]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]
d3wjta__d1iwma___1				Proteobacteria		cell outer membrane [GO:0009279]; lipopeptide binding [GO:0071723]; lipid localization [GO:0010876]; lipoprotein localization to outer membrane [GO:0044874]; lipoprotein metabolic process [GO:0042157]; localization within membrane [GO:0051668]; protein transport [GO:0015031]		lipid localization [GO:0010876]; lipoprotein localization to outer membrane [GO:0044874]; lipoprotein metabolic process [GO:0042157]; localization within membrane [GO:0051668]; protein transport [GO:0015031]		cell outer membrane [GO:0009279]		lipopeptide binding [GO:0071723]
d3wjua__d3wjva___1												
d3wk5a1_d1l6ra1__1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	magnesium ion binding [GO:0000287]; phosphoglycolate phosphatase activity [GO:0008967]; carbohydrate metabolic process [GO:0005975]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	carbohydrate metabolic process [GO:0005975]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	magnesium ion binding [GO:0000287]; phosphoglycolate phosphatase activity [GO:0008967]
d3wk5a2_d4gi1b___1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipid catabolic process [GO:0016042]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	triglyceride lipase activity [GO:0004806]
d3wk6a2_d1gz7a___1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipid catabolic process [GO:0016042]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	triglyceride lipase activity [GO:0004806]
d3wk7a1_d1nf2c___1	Metazoa		Chordata	Thermotogae	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cytosol [GO:0005829]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]
d3wk7a2_d1ji3a___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	metal ion binding [GO:0046872]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	metal ion binding [GO:0046872]
d3wk8a2_d4yx9b___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	
d3wkaa2_d1nu8a2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3wkca2_d3eq7a2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d3wkda1_d3mn1a1__1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipopolysaccharide biosynthetic process [GO:0009103]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d3wkda2_d1hplb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	extracellular space [GO:0005615]; lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]; lipid catabolic process [GO:0016042]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	lipid catabolic process [GO:0016042]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	extracellular space [GO:0005615]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	lipase activity [GO:0016298]; metal ion binding [GO:0046872]; triglyceride lipase activity [GO:0004806]
d3wkea1_d1rmwb___1	Metazoa		Chordata		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	
d3wkga__d5gy3a___1			Bacteroidetes	Proteobacteria	cellobiose epimerase activity [GO:0047736]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]		polysaccharide catabolic process [GO:0000272]			cellobiose epimerase activity [GO:0047736]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3wkia__d1xwta1__1			Bacteroidetes	Proteobacteria	cellobiose epimerase activity [GO:0047736]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]		xylan catabolic process [GO:0045493]			cellobiose epimerase activity [GO:0047736]	endo-1,4-beta-xylanase activity [GO:0031176]
d3wkja__d2yfwh___1	Metazoa	Fungi	Chordata	Ascomycota	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	2-micrometer circle DNA [GO:0005729]; CENP-A containing nucleosome [GO:0043505]; condensed chromosome kinetochore [GO:0000777]; condensed nuclear chromosome, centromeric region [GO:0000780]; centromeric DNA binding [GO:0019237]; protein heterodimerization activity [GO:0046982]; 2-micrometer plasmid partitioning [GO:0030543]; kinetochore assembly [GO:0051382]; mitotic sister chromatid segregation [GO:0000070]; protein localization to CENP-A containing chromatin [GO:0061644]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	2-micrometer plasmid partitioning [GO:0030543]; kinetochore assembly [GO:0051382]; mitotic sister chromatid segregation [GO:0000070]; protein localization to CENP-A containing chromatin [GO:0061644]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	2-micrometer circle DNA [GO:0005729]; CENP-A containing nucleosome [GO:0043505]; condensed chromosome kinetochore [GO:0000777]; condensed nuclear chromosome, centromeric region [GO:0000780]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	centromeric DNA binding [GO:0019237]; protein heterodimerization activity [GO:0046982]
d3wkjd__d4nftc2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nucleosome [GO:0000786]; nucleus [GO:0005634]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; nucleosomal DNA binding [GO:0031492]; protein heterodimerization activity [GO:0046982]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; cellular response to estradiol stimulus [GO:0071392]; chromatin organization [GO:0006325]; positive regulation of transcription by RNA polymerase II [GO:0045944]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular response to estradiol stimulus [GO:0071392]; chromatin organization [GO:0006325]; positive regulation of transcription by RNA polymerase II [GO:0045944]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	extracellular exosome [GO:0070062]; nuclear chromatin [GO:0000790]; nuclear euchromatin [GO:0005719]; nuclear heterochromatin [GO:0005720]; nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; nucleosomal DNA binding [GO:0031492]; protein heterodimerization activity [GO:0046982]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d3wkje__d3azjg___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3wkjh__d1eqzb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	cellular protein metabolic process [GO:0044267]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin silencing at rDNA [GO:0000183]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of megakaryocyte differentiation [GO:0045653]; nucleosome assembly [GO:0006334]; protein heterotetramerization [GO:0051290]; regulation of gene silencing by miRNA [GO:0060964]; regulation of megakaryocyte differentiation [GO:0045652]; telomere capping [GO:0016233]; telomere organization [GO:0032200]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear chromosome [GO:0000228]; nuclear chromosome, telomeric region [GO:0000784]; nuclear nucleosome [GO:0000788]; nucleoplasm [GO:0005654]; nucleosome [GO:0000786]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	nucleosome [GO:0000786]; nucleus [GO:0005634]	DNA binding [GO:0003677]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d3wkml1_d8fabd1__1			Aquificae		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]				integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	
d3wkmm1_d1t04d1__1			Aquificae		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]				integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	
d3wkmm1_d4s1ql1__1			Aquificae		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	viral envelope [GO:0019031]; virion membrane [GO:0055036]; membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]		membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	viral envelope [GO:0019031]; virion membrane [GO:0055036]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	
d3wkmm2_d5xajc2__1			Aquificae		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]				integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	
d3wlha1_d3amca___1	Viridiplantae		Streptophyta	Thermotogae	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3wlia1_d3aztb___1	Viridiplantae		Streptophyta	Thermotogae	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	carbohydrate metabolic process [GO:0005975]	cellular glucan metabolic process [GO:0006073]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3wlja1_d1bvnp2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]		extracellular space [GO:0005615]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d3wlkx1_d2wt6a1__1	Viridiplantae		Streptophyta		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	
d3wlma1_d5m16a2__1	Viridiplantae		Streptophyta	Thermotogae	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	alpha-galactosidase activity [GO:0004557]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; carbohydrate metabolic process [GO:0005975]; glycoside catabolic process [GO:0016139]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; glycoside catabolic process [GO:0016139]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alpha-galactosidase activity [GO:0004557]; carbohydrate binding [GO:0030246]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]
d3wlna1_d1h11a___1	Viridiplantae		Streptophyta	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]
d3wlpa1_d5i77a1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulase activity [GO:0008810]
d3wlra1_d2uy3a___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	cellular bud neck [GO:0005935]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; fungal-type vacuole [GO:0000324]; nuclear envelope [GO:0005635]; chitin binding [GO:0008061]; endochitinase activity [GO:0008843]; cell wall organization [GO:0071555]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]; septum digestion after cytokinesis [GO:0000920]	carbohydrate metabolic process [GO:0005975]	cell wall organization [GO:0071555]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]; septum digestion after cytokinesis [GO:0000920]		cellular bud neck [GO:0005935]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; fungal-type vacuole [GO:0000324]; nuclear envelope [GO:0005635]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	chitin binding [GO:0008061]; endochitinase activity [GO:0008843]
d3wlta1_d4nxsa1__1		Metazoa		Chordata		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]		alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d3wlub__d2dtwd___1	Metazoa	Viridiplantae	Chordata	Streptophyta	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	carbohydrate binding [GO:0030246]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]		collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	carbohydrate binding [GO:0030246]
d3wlud__d4h7ma1__1	Metazoa	Fungi	Chordata	Ascomycota	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	polysaccharide catabolic process [GO:0000272]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]		carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	cellulase activity [GO:0008810]
d3wmdb1_d5wica___1			Actinobacteria	Proteobacteria	isomerase activity [GO:0016853]	integral component of membrane [GO:0016021]; protein secretion by the type IV secretion system [GO:0030255]		protein secretion by the type IV secretion system [GO:0030255]		integral component of membrane [GO:0016021]	isomerase activity [GO:0016853]	
d3wmnc__d3prcc___1				Proteobacteria		plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]		photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]		plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3wmoh2_d3i4dh2__1				Proteobacteria		integral component of membrane [GO:0016021]; plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]		photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]		integral component of membrane [GO:0016021]; plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]		bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]
d3wmsa1_d3mv133__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3wmsa2_d4hoza2__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d3wn5a1_d4c83d1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		IgG binding [GO:0019864]	
d3wn5a2_d1iaob1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of T cell differentiation [GO:0045582]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]	IgG binding [GO:0019864]	peptide antigen binding [GO:0042605]; protein heterodimerization activity [GO:0046982]
d3wn5a2_d1tzgl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		IgG binding [GO:0019864]	
d3wn5b1_d4n9ob1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]; activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	activation of protein kinase activity [GO:0032147]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell cycle arrest [GO:0007050]; cellular copper ion homeostasis [GO:0006878]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to drug [GO:0035690]; dendritic spine maintenance [GO:0097062]; epithelial cell differentiation [GO:0030855]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-17 production [GO:0032700]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neuron projection maintenance [GO:1990535]; Notch signaling pathway [GO:0007219]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein tyrosine kinase activity [GO:0061098]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of intracellular calcium activated chloride channel activity [GO:1902938]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amyloid-beta [GO:1904645]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	anchored component of external side of plasma membrane [GO:0031362]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; inclusion body [GO:0016234]; intracellular membrane-bounded organelle [GO:0043231]; membrane raft [GO:0045121]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]	IgG binding [GO:0019864]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase inhibitor activity [GO:0019828]; ATP-dependent protein binding [GO:0043008]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; chaperone binding [GO:0051087]; chondroitin sulfate binding [GO:0035374]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; glycosaminoglycan binding [GO:0005539]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; lamin binding [GO:0005521]; microtubule binding [GO:0008017]; protease binding [GO:0002020]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; tubulin binding [GO:0015631]; type 5 metabotropic glutamate receptor binding [GO:0031802]
d3wn5b2_d2fjfl1__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		IgG binding [GO:0019864]	
d3wn5d1_d5v7rl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		IgG binding [GO:0019864]	
d3wn5d2_d1zhnb___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	IgG binding [GO:0019864]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3wn5d2_d3cfbl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	IgG binding [GO:0019864]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3wn5e2_d3muhl2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]		IgG binding [GO:0019864]	
d3wn5e2_d4om1l2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; IgG binding [GO:0019864]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; regulation of immune response [GO:0050776]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	IgG binding [GO:0019864]	structural molecule activity [GO:0005198]
d3wnra__d2os5c___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]		chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	cytokine receptor binding [GO:0005126]; metal ion binding [GO:0046872]
d3wnsa__d4xx7a___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]; chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]; carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	carboxylic acid metabolic process [GO:0019752]; cell aging [GO:0007569]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-12-mediated signaling pathway [GO:0035722]; leukocyte migration [GO:0050900]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of macrophage chemotaxis [GO:0010760]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; neutrophil degranulation [GO:0043312]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphorylation [GO:0042327]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]; regulation of macrophage activation [GO:0043030]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; vesicle [GO:0031982]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]	chemoattractant activity [GO:0042056]; cytokine activity [GO:0005125]; cytokine receptor binding [GO:0005126]; dopachrome isomerase activity [GO:0004167]; identical protein binding [GO:0042802]; phenylpyruvate tautomerase activity [GO:0050178]; protease binding [GO:0002020]; signaling receptor binding [GO:0005102]
d3wnua2_d4fcna___1		Fungi	Cyanobacteria	Basidiomycota	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]		extracellular region [GO:0005576]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]
d3wnwa__d4cmyj___1	Metazoa		Chordata	Chlorobi	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]
d3wnwb__d3rnea___1	Metazoa		Chordata	Proteobacteria	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cellular aromatic compound metabolic process [GO:0006725]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d3wnwc__d3isec___1	Metazoa		Chordata	Proteobacteria	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3wnwd__d3re7x___1	Metazoa	Metazoa	Chordata	Chordata	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3wnwf__d3rbcx___1	Metazoa	Metazoa	Chordata	Chordata	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3wnwg__d1xmfd___1	Metazoa		Chordata	Proteobacteria	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]		ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d3wnwg__d2jd7q___1	Metazoa		Chordata	Euryarchaeota	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]
d3wnwi__d3e2cb___1	Metazoa		Chordata	Proteobacteria	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d3wnxa__d3l2yr___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]; calcium ion binding [GO:0005509]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein N-linked glycosylation via asparagine [GO:0018279]; protein transport [GO:0015031]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum membrane [GO:0005789]; ER to Golgi transport vesicle membrane [GO:0012507]; Golgi membrane [GO:0000139]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d3wo2d__d3cu1b___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3wo3i__d1irpa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]; cytokine activity [GO:0005125]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; interleukin-1 type I receptor antagonist activity [GO:0045352]; interleukin-1 type II receptor antagonist activity [GO:0045353]; interleukin-1, type I receptor binding [GO:0005150]; interleukin-1, type II receptor binding [GO:0005151]; acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; interleukin-1-mediated signaling pathway [GO:0070498]; lipid metabolic process [GO:0006629]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; response to glucocorticoid [GO:0051384]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	acute-phase response [GO:0006953]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; immune response [GO:0006955]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; interleukin-1-mediated signaling pathway [GO:0070498]; lipid metabolic process [GO:0006629]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; neutrophil chemotaxis [GO:0030593]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; response to glucocorticoid [GO:0051384]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]	cytokine activity [GO:0005125]; interleukin-1, type II receptor binding [GO:0005151]; interleukin-1, type I receptor binding [GO:0005150]; interleukin-1 receptor antagonist activity [GO:0005152]; interleukin-1 receptor binding [GO:0005149]; interleukin-1 type II receptor antagonist activity [GO:0045353]; interleukin-1 type I receptor antagonist activity [GO:0045352]
d3wo4a__d1t4qa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]; activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]; cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]; activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	activation of protein kinase B activity [GO:0032148]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; cell population proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; chemokine biosynthetic process [GO:0042033]; cholesterol homeostasis [GO:0042632]; cytokine-mediated signaling pathway [GO:0019221]; granulocyte macrophage colony-stimulating factor biosynthetic process [GO:0042253]; inflammatory response [GO:0006954]; interferon-gamma biosynthetic process [GO:0042095]; interleukin-13 biosynthetic process [GO:0042231]; interleukin-18-mediated signaling pathway [GO:0035655]; interleukin-2 biosynthetic process [GO:0042094]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; natural killer cell activation [GO:0030101]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of myoblast differentiation [GO:0045662]; neutrophil activation [GO:0042119]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of NK T cell proliferation [GO:0051142]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of tissue remodeling [GO:0034105]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; regulation of cell adhesion [GO:0030155]; sleep [GO:0030431]; T-helper 1 cell cytokine production [GO:0035744]; T-helper 1 type immune response [GO:0042088]; triglyceride homeostasis [GO:0070328]; type 2 immune response [GO:0042092]	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; cell-cell signaling [GO:0007267]; cellular response to drug [GO:0035690]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cytokine-mediated signaling pathway [GO:0019221]; ectopic germ cell programmed cell death [GO:0035234]; embryo implantation [GO:0007566]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fever generation [GO:0001660]; hyaluronan biosynthetic process [GO:0030213]; immune response [GO:0006955]; inflammatory response [GO:0006954]; interleukin-1 beta production [GO:0032611]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-6 production [GO:0032635]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; monocyte aggregation [GO:0070487]; negative regulation of adiponectin secretion [GO:0070164]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of glucose transmembrane transport [GO:0010829]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid metabolic process [GO:0045833]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurogenesis [GO:0050768]; negative regulation of synaptic transmission [GO:0050805]; neutrophil chemotaxis [GO:0030593]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of complement activation [GO:0045917]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of phagocytosis [GO:0050766]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of prostaglandin secretion [GO:0032308]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA biosynthetic process [GO:1902680]; positive regulation of T cell mediated immunity [GO:0002711]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 1 cell cytokine production [GO:2000556]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein kinase B signaling [GO:0043491]; regulation of defense response to virus by host [GO:0050691]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of nitric-oxide synthase activity [GO:0050999]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; sequestering of triglyceride [GO:0030730]; signal transduction [GO:0007165]; smooth muscle adaptation [GO:0014805]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; secretory granule [GO:0030141]	cytokine activity [GO:0005125]; interleukin-18 receptor binding [GO:0045515]	cytokine activity [GO:0005125]; integrin binding [GO:0005178]; interleukin-1 receptor binding [GO:0005149]; protein domain specific binding [GO:0019904]
d3woga__d4hkwa1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	mannose binding [GO:0005537]; toxin activity [GO:0090729]; defense response [GO:0006952]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	defense response [GO:0006952]	xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	mannose binding [GO:0005537]; toxin activity [GO:0090729]	endo-1,4-beta-xylanase activity [GO:0031176]
d3wp3a__d1reeb1__1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]	endo-1,4-beta-xylanase activity [GO:0031176]
d3wp6a__d2rfwa___1	Fungi	Fungi	Chytridiomycota	Ascomycota	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3wpla__d1cu0a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3wptb__d4u54a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; RNA binding [GO:0003723]; DNA metabolic process [GO:0006259]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; modulation by virus of host cellular process [GO:0019054]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; regulation of DNA recombination [GO:0000018]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]; histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	DNA metabolic process [GO:0006259]; entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; modulation by virus of host cellular process [GO:0019054]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; regulation of DNA recombination [GO:0000018]	entry of viral genome into host nucleus through nuclear pore complex via importin [GO:0075506]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of viral life cycle [GO:1903902]; postsynapse to nucleus signaling pathway [GO:0099527]; protein import into nucleus [GO:0006606]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; membrane [GO:0016020]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]	cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; extrinsic component of postsynaptic specialization membrane [GO:0098892]; glutamatergic synapse [GO:0098978]; host cell [GO:0043657]; nuclear pore [GO:0005643]; nucleoplasm [GO:0005654]	histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; RNA binding [GO:0003723]	histone deacetylase binding [GO:0042826]; nuclear import signal receptor activity [GO:0061608]; nuclear localization sequence binding [GO:0008139]; repressing transcription factor binding [GO:0070491]
d3wq5a__d3ahvb___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102402]; beta-primeverosidase activity [GO:0050535]; linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102404]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular region [GO:0005576]	2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102402]; beta-primeverosidase activity [GO:0050535]; linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102404]	amygdalin beta-glucosidase activity [GO:0047668]; beta-D-fucosidase activity [GO:0033907]; beta-galactosidase activity [GO:0004565]; beta-gentiobiose beta-glucosidase activity [GO:0080083]; beta-glucosidase activity [GO:0008422]; beta-L-arabinosidase activity [GO:0047701]; beta-mannosidase activity [GO:0004567]; cellobiose glucosidase activity [GO:0080079]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; protein homodimerization activity [GO:0042803]; prunasin beta-glucosidase activity [GO:0050224]; scopolin beta-glucosidase activity [GO:0102483]
d3wq6a__d2xuca1__1	Viridiplantae	Fungi	Streptophyta	Ascomycota	2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102402]; beta-primeverosidase activity [GO:0050535]; linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102404]; carbohydrate metabolic process [GO:0005975]	anchored component of membrane [GO:0031225]; cell wall [GO:0005618]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		anchored component of membrane [GO:0031225]; cell wall [GO:0005618]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102402]; beta-primeverosidase activity [GO:0050535]; linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102404]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d3wq6b__d1y7vb2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102402]; beta-primeverosidase activity [GO:0050535]; linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102404]; carbohydrate metabolic process [GO:0005975]	endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]; glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]	carbohydrate metabolic process [GO:0005975]	autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; cholesterol metabolic process [GO:0008203]; glucosylceramide catabolic process [GO:0006680]; glycosphingolipid metabolic process [GO:0006687]; lipid glycosylation [GO:0030259]; lysosome organization [GO:0007040]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron death [GO:1901215]; negative regulation of protein complex assembly [GO:0031333]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; regulation of cellular protein metabolic process [GO:0032268]; regulation of lysosomal protein catabolic process [GO:1905165]; regulation of macroautophagy [GO:0016241]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; termination of signal transduction [GO:0023021]		endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; trans-Golgi network [GO:0005802]	2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102402]; beta-primeverosidase activity [GO:0050535]; linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity [GO:0102404]	glucosylceramidase activity [GO:0004348]; glucosyltransferase activity [GO:0046527]; hydrolase activity [GO:0016787]; scavenger receptor binding [GO:0005124]; signaling receptor binding [GO:0005102]; steryl-beta-glucosidase activity [GO:0050295]
d3wq8a__d3vdbc3__1			Euryarchaeota	Proteobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3wq8g__d4w8la___1			Euryarchaeota	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; endo-1,4-beta-xylanase activity [GO:0031176]
d3wq8h__d1uz4a___1			Euryarchaeota	Proteobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3wqhb1_d2i3zb1__1	Metazoa	Metazoa	Chordata	Chordata	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; establishment of localization [GO:0051234]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; regulation of T cell mediated immunity [GO:0002709]; T cell costimulation [GO:0031295]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cell junction [GO:0030054]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]	collagen binding [GO:0005518]; dipeptidyl-peptidase activity [GO:0008239]; peptide binding [GO:0042277]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]
d3wqpa1_d1aa1e2__1		Viridiplantae	Euryarchaeota	Streptophyta	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]; AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]	AMP catabolic process [GO:0006196]; carbon fixation [GO:0015977]	carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		chloroplast [GO:0009507]	magnesium ion binding [GO:0000287]; oxidoreductase activity [GO:0016491]; ribulose-bisphosphate carboxylase activity [GO:0016984]	monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3wrha__d3na0a___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	(+)-camphor catabolic process [GO:0019383]	C21-steroid hormone biosynthetic process [GO:0006700]; cellular response to cAMP [GO:0071320]; cellular response to forskolin [GO:1904322]; cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; small molecule metabolic process [GO:0044281]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; iron ion binding [GO:0005506]
d3wrhe__d2fdyb1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d3wrja__d2zuja___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	(+)-camphor catabolic process [GO:0019383]	(+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3wrja__d3l4db1__1			Proteobacteria		cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d3wrla__d3t3sh___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	(+)-camphor catabolic process [GO:0019383]	coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d3wrma__d4g7gc___1			Proteobacteria		cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	(+)-camphor catabolic process [GO:0019383]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d3ws7a1_d5pgxb1__1		Metazoa	Crenarchaeota	Chordata	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d3ws7a1_d5u1pa___1			Crenarchaeota	Proteobacteria	NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	carbonyl reductase (NADPH) activity [GO:0004090]; nucleotide binding [GO:0000166]					NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity [GO:0016491]	carbonyl reductase (NADPH) activity [GO:0004090]; nucleotide binding [GO:0000166]
d3ws8a1_d3ecna___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cellular response to epidermal growth factor stimulus [GO:0071364]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; regulation of transcription, DNA-templated [GO:0006355]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; cellular response to epidermal growth factor stimulus [GO:0071364]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]
d3wsba__d2q9za___1		Fungi		Ascomycota	integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]; ergosterol biosynthetic process [GO:0006696]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]; sesquiterpenoid biosynthetic process [GO:0016106]	ergosterol biosynthetic process [GO:0006696]	sesquiterpenoid biosynthetic process [GO:0016106]	integral component of membrane [GO:0016021]		farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]	metal ion binding [GO:0046872]; trichodiene synthase activity [GO:0045482]
d3wsbc__d3wcdb___1		Metazoa		Chordata	integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]; ergosterol biosynthetic process [GO:0006696]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]; cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	ergosterol biosynthetic process [GO:0006696]	cholesterol biosynthetic process [GO:0006695]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of lipid metabolic process [GO:0019216]; steroid biosynthetic process [GO:0006694]	integral component of membrane [GO:0016021]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; squalene synthase activity [GO:0051996]	farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; metal ion binding [GO:0046872]; squalene synthase activity [GO:0051996]
d3wsdd__d1nmpd___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; response to ionizing radiation [GO:0010212]		DNA repair [GO:0006281]; response to ionizing radiation [GO:0010212]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3wsfc__d1nmpe___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; response to ionizing radiation [GO:0010212]		DNA repair [GO:0006281]; response to ionizing radiation [GO:0010212]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3wshf__d1nmpb___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; response to ionizing radiation [GO:0010212]		DNA repair [GO:0006281]; response to ionizing radiation [GO:0010212]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3wshj__d1nmpa___1				Proteobacteria		cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; response to ionizing radiation [GO:0010212]		DNA repair [GO:0006281]; response to ionizing radiation [GO:0010212]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3wspa__d3gw9a___1			Firmicutes		cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]
d3wsub__d2vrjb___1			Actinobacteria	Thermotogae	cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; cellulose catabolic process [GO:0030245]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]			cellulase activity [GO:0008810]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]
d3wsvb1_d3mw9d1__1			Firmicutes		cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	
d3wswb1_d1lnqa3__1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; glycolytic process [GO:0006096]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; potassium ion transport [GO:0006813]	glycolytic process [GO:0006096]	potassium ion transport [GO:0006813]	cytoplasm [GO:0005737]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	cation transmembrane transporter activity [GO:0008324]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3wswb1_d5lc1e1__1			Firmicutes		cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; glycolytic process [GO:0006096]	coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]	glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]	coenzyme binding [GO:0050662]; L-threonine 3-dehydrogenase activity [GO:0008743]; nucleotide binding [GO:0000166]
d3wtba1_d1ntoa2__1			Proteobacteria	Crenarchaeota	oxidoreductase activity [GO:0016491]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]					oxidoreductase activity [GO:0016491]	alcohol dehydrogenase (NAD+) activity [GO:0004022]; zinc ion binding [GO:0008270]
d3wtbc__d1lrla___1			Proteobacteria	Proteobacteria	oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]; carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]		carbohydrate metabolic process [GO:0005975]; colanic acid biosynthetic process [GO:0009242]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	oxidoreductase activity [GO:0016491]	identical protein binding [GO:0042802]; NAD+ binding [GO:0070403]; racemase and epimerase activity, acting on carbohydrates and derivatives [GO:0016857]; UDP-glucose 4-epimerase activity [GO:0003978]
d3wtbe__d2iypa1__1			Proteobacteria	Firmicutes	oxidoreductase activity [GO:0016491]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]; D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]		D-gluconate metabolic process [GO:0019521]; pentose-phosphate shunt [GO:0006098]			oxidoreductase activity [GO:0016491]	NADP binding [GO:0050661]; phosphogluconate dehydrogenase (decarboxylating) activity [GO:0004616]
d3wtbf__d3aogb2__1			Proteobacteria	Deinococcus-Thermus	oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]		cellular amino acid metabolic process [GO:0006520]			oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d3wtbg__d2wywb___1			Proteobacteria	Deinococcus-Thermus	oxidoreductase activity [GO:0016491]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]			oxidoreductase activity [GO:0016491]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; nucleotide binding [GO:0000166]
d3wtbh__d2gf2d1__1		Metazoa	Proteobacteria	Chordata	oxidoreductase activity [GO:0016491]	mitochondrial matrix [GO:0005759]; 3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574]		branched-chain amino acid catabolic process [GO:0009083]; valine catabolic process [GO:0006574]		mitochondrial matrix [GO:0005759]	oxidoreductase activity [GO:0016491]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d3wtbh__d4dc0b___1			Proteobacteria	Actinobacteria	oxidoreductase activity [GO:0016491]	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]		antibiotic biosynthetic process [GO:0017000]			oxidoreductase activity [GO:0016491]	oxidoreductase activity [GO:0016491]
d3wtca__d5ijzi2__1			Proteobacteria	Actinobacteria	acetoin dehydrogenase activity [GO:0019152]; acetoin catabolic process [GO:0045150]	cytoplasm [GO:0005737]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; glutamate biosynthetic process [GO:0006537]	acetoin catabolic process [GO:0045150]	glutamate biosynthetic process [GO:0006537]		cytoplasm [GO:0005737]	acetoin dehydrogenase activity [GO:0019152]	glutamate dehydrogenase (NADP+) activity [GO:0004354]
d3wtgb__d2uulq___1	Metazoa		Chordata		hemoglobin complex [GO:0005833]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]				hemoglobin complex [GO:0005833]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	
d3wtha1_d3t4mf1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wthd1_d4xk9g___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtid1_d2w8fc___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtie1_d5hbtb1__1	Metazoa	Metazoa	Mollusca	Chordata	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	acetylcholine-gated channel complex [GO:0005892]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic specialization membrane [GO:0099060]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; acetylcholine binding [GO:0042166]; acetylcholine receptor activity [GO:0015464]; acetylcholine-gated cation-selective channel activity [GO:0022848]; ion channel activity [GO:0005216]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; muscle cell cellular homeostasis [GO:0046716]; musculoskeletal movement [GO:0050881]; nervous system process [GO:0050877]; neuromuscular junction development [GO:0007528]; neuromuscular process [GO:0050905]; neuromuscular synaptic transmission [GO:0007274]; neuron cellular homeostasis [GO:0070050]; neuronal action potential [GO:0019228]; regulation of membrane potential [GO:0042391]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; skeletal muscle contraction [GO:0003009]; skeletal muscle tissue growth [GO:0048630]; synaptic transmission, cholinergic [GO:0007271]		chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; muscle cell cellular homeostasis [GO:0046716]; musculoskeletal movement [GO:0050881]; nervous system process [GO:0050877]; neuromuscular junction development [GO:0007528]; neuromuscular process [GO:0050905]; neuromuscular synaptic transmission [GO:0007274]; neuronal action potential [GO:0019228]; neuron cellular homeostasis [GO:0070050]; regulation of membrane potential [GO:0042391]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; skeletal muscle contraction [GO:0003009]; skeletal muscle tissue growth [GO:0048630]; synaptic transmission, cholinergic [GO:0007271]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	acetylcholine-gated channel complex [GO:0005892]; cell [GO:0005623]; cell junction [GO:0030054]; cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic specialization membrane [GO:0099060]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	acetylcholine binding [GO:0042166]; acetylcholine-gated cation-selective channel activity [GO:0022848]; acetylcholine receptor activity [GO:0015464]; ion channel activity [GO:0005216]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3wtja1_d2c9tg___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtka1_d2br7e___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtkd1_d2xz6f___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtke1_d4afod___1	Metazoa		Mollusca		cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]				cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]		extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	
d3wtma1_d5lxbj___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtmb1_d1ux2b___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3wtme1_d3c84a1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtna1_d1uw6f___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3wtna1_d2ymdg___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtnc1_d4afgb___1	Metazoa	Metazoa	Mollusca	Annelida	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]
d3wtnd1_d2byre1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtnf1_d4xhej1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtng1_d2xysa___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtnh1_d2xnvf___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtni1_d2w8ff___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtoc1_d2wzyi1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3wtoc1_d3sq9i___1	Metazoa		Mollusca		cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]				cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]		extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	
d3wtod1_d1uw6c___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d3wtsa1_d1hjcd___1	Metazoa	Metazoa	Chordata	Chordata	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3wtvf__d4ibub___1	Metazoa	Metazoa	Chordata	Chordata	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d3wtwc__d1u6ga1__1	Metazoa	Metazoa	Chordata	Chordata	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	cell [GO:0005623]; cullin-RING ubiquitin ligase complex [GO:0031461]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; ubiquitin ligase complex [GO:0000151]; TBP-class protein binding [GO:0017025]; cell differentiation [GO:0030154]; cellular iron ion homeostasis [GO:0006879]; negative regulation of catalytic activity [GO:0043086]; neutrophil degranulation [GO:0043312]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; SCF complex assembly [GO:0010265]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	cell differentiation [GO:0030154]; cellular iron ion homeostasis [GO:0006879]; negative regulation of catalytic activity [GO:0043086]; neutrophil degranulation [GO:0043312]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; SCF complex assembly [GO:0010265]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cullin-RING ubiquitin ligase complex [GO:0031461]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; secretory granule lumen [GO:0034774]; ubiquitin ligase complex [GO:0000151]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]	TBP-class protein binding [GO:0017025]
d3wtxa__d1hjbc___1	Metazoa	Metazoa	Chordata	Chordata	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	cell maturation [GO:0048469]; definitive hemopoiesis [GO:0060216]; lymphocyte differentiation [GO:0030098]; myeloid cell differentiation [GO:0030099]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of transcription by RNA polymerase II [GO:0000122]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein polyubiquitination [GO:0000209]	behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	core-binding factor complex [GO:0016513]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	basement membrane [GO:0005604]; core-binding factor complex [GO:0016513]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]	ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; promoter-specific chromatin binding [GO:1990841]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific double-stranded DNA binding [GO:1990837]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d3wu0a__d5e8gc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; animal organ morphogenesis [GO:0009887]; blood circulation [GO:0008015]; cell differentiation [GO:0030154]; hemostasis [GO:0007599]; megakaryocyte development [GO:0035855]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	animal organ morphogenesis [GO:0009887]; blood circulation [GO:0008015]; cell differentiation [GO:0030154]; hemostasis [GO:0007599]; megakaryocyte development [GO:0035855]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytosol [GO:0005829]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d3wu0b__d2pi0c___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	angiogenesis involved in wound healing [GO:0060055]; cell differentiation [GO:0030154]; cell motility [GO:0048870]; cellular response to hydrogen peroxide [GO:0070301]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; hypothalamus development [GO:0021854]; immune response [GO:0006955]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inflammatory response [GO:0050728]; pituitary gland development [GO:0021983]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pri-miRNA transcription by RNA polymerase II [GO:0061614]; regulation of angiogenesis [GO:0045765]; regulation of apoptotic process [GO:0042981]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of transcription by RNA polymerase II [GO:0006357]; response to antibiotic [GO:0046677]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to laminar fluid shear stress [GO:0034616]; response to mechanical stimulus [GO:0009612]; transcription by RNA polymerase II [GO:0006366]	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; interferon-gamma-mediated signaling pathway [GO:0060333]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; macrophage apoptotic process [GO:0071888]; MDA-5 signaling pathway [GO:0039530]; negative regulation of type I interferon production [GO:0032480]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type I interferon production [GO:0032481]; programmed necrotic cell death [GO:0097300]; regulation of inflammatory response [GO:0050727]; regulation of type I interferon production [GO:0032479]; transcription by RNA polymerase II [GO:0006366]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon biosynthetic process [GO:0045351]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; histone acetyltransferase binding [GO:0035035]; identical protein binding [GO:0042802]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; transcription coregulator activity [GO:0003712]
d3wu5e__d5drpa1__1				Aquificae		metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]; lipid A biosynthetic process [GO:0009245]		lipid A biosynthetic process [GO:0009245]				metal ion binding [GO:0046872]; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [GO:0008759]; UDP-3-O-acyl-N-acetylglucosamine deacetylase activity [GO:0103117]
d3wu5f__d2cz9a1__1				Euryarchaeota		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; galactokinase activity [GO:0004335]; galactose binding [GO:0005534]; magnesium ion binding [GO:0000287]; galactose metabolic process [GO:0006012]		galactose metabolic process [GO:0006012]		cytoplasm [GO:0005737]		ATP binding [GO:0005524]; galactokinase activity [GO:0004335]; galactose binding [GO:0005534]; magnesium ion binding [GO:0000287]
d3wu6a__d1hnxi___1				Deinococcus-Thermus		ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]		translation [GO:0006412]		ribosome [GO:0005840]		rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d3wu6b__d2c37v1__1				Crenarchaeota		cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]		rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]
d3wu6c__d4loma1__1												
d3wu6d__d2c39v1__1				Crenarchaeota		cytoplasmic exosome (RNase complex) [GO:0000177]; 3'-5'-exoribonuclease activity [GO:0000175]; rRNA catabolic process [GO:0016075]		rRNA catabolic process [GO:0016075]		cytoplasmic exosome (RNase complex) [GO:0000177]		3'-5'-exoribonuclease activity [GO:0000175]
d3wu6e__d1oyrf1__1				Firmicutes		3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]		rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; tRNA processing [GO:0008033]				3'-5'-exoribonuclease activity [GO:0000175]; tRNA binding [GO:0000049]; tRNA nucleotidyltransferase activity [GO:0009022]
d3wuaa__d258la___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3wuca__d4yz3b1__1	Metazoa		Chordata	Firmicutes	carbohydrate binding [GO:0030246]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]			carbohydrate binding [GO:0030246]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d3wuna__d4i7kb1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3wv1a__d5nida2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]; aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular lipid metabolic process [GO:0044255]; cellular protein metabolic process [GO:0044267]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid biosynthetic process [GO:0042759]; neutrophil degranulation [GO:0043312]; peptide catabolic process [GO:0043171]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; tertiary granule lumen [GO:1904724]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	aminopeptidase activity [GO:0004177]; epoxide hydrolase activity [GO:0004301]; leukotriene-A4 hydrolase activity [GO:0004463]; metalloaminopeptidase activity [GO:0070006]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d3wv6a1_d3pvoe___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d3wv6b2_d5jowb2__1	Metazoa		Chordata	Bacteroidetes	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]; cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	periplasmic space [GO:0042597]; alpha-L-arabinofuranosidase activity [GO:0046556]; symbiotic process benefiting host [GO:0085030]; xyloglucan catabolic process [GO:2000899]	cellular response to interferon-gamma [GO:0071346]; cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; ERK1 and ERK2 cascade [GO:0070371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; maternal process involved in female pregnancy [GO:0060135]; natural killer cell tolerance induction [GO:0002519]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of chemokine production [GO:0032682]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of tumor necrosis factor production [GO:0032720]; p38MAPK cascade [GO:0038066]; positive regulation of activated T cell autonomous cell death [GO:0070241]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response [GO:0032834]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of dendritic cell differentiation [GO:2001200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma secretion [GO:1902715]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-12 secretion [GO:2001184]; positive regulation of interleukin-13 secretion [GO:2000667]; positive regulation of interleukin-1 beta secretion [GO:0050718]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of interleukin-8 secretion [GO:2000484]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of tumor necrosis factor secretion [GO:1904469]; positive regulation of viral entry into host cell [GO:0046598]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]	symbiotic process benefiting host [GO:0085030]; xyloglucan catabolic process [GO:2000899]	collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	periplasmic space [GO:0042597]	carbohydrate binding [GO:0030246]; disaccharide binding [GO:0048030]; enzyme binding [GO:0019899]; galactose binding [GO:0005534]; galactoside binding [GO:0016936]	alpha-L-arabinofuranosidase activity [GO:0046556]
d3wveb__d3a8lb___1			Actinobacteria	Actinobacteria	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d3wveb__d3qz9d___1			Actinobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	
d3wvjb__d1upsa1__1			Firmicutes	Firmicutes	licheninase activity [GO:0042972]; polysaccharide catabolic process [GO:0000272]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]			licheninase activity [GO:0042972]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d3wvva__d5ww7c___1	Metazoa		Chordata	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d3wvwa__d4toev___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; intracellular ferritin complex [GO:0008043]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d3wvya__d1uica___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3ww5a__d1pqja___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3ww5a__d3j6ka___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3ww6a__d8lyza___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d3wwgc2_d2ntpa___1	Fungi		Ascomycota	Proteobacteria	extracellular region [GO:0005576]; isopullulanase activity [GO:0051675]; metabolic process [GO:0008152]	extracellular region [GO:0005576]; aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]; cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	metabolic process [GO:0008152]	cell wall modification [GO:0042545]; pectin catabolic process [GO:0045490]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	isopullulanase activity [GO:0051675]	aspartyl esterase activity [GO:0045330]; pectinesterase activity [GO:0030599]
d3wwkb__d1o7bt___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; hyaluronic acid binding [GO:0005540]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; inflammatory response [GO:0006954]; negative regulation of inflammatory response [GO:0050728]; neutrophil degranulation [GO:0043312]; ovulation [GO:0030728]; positive regulation of cell migration [GO:0030335]; signal transduction [GO:0007165]	regulation of cytokine activity [GO:0060300]	cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; inflammatory response [GO:0006954]; negative regulation of inflammatory response [GO:0050728]; neutrophil degranulation [GO:0043312]; ovulation [GO:0030728]; positive regulation of cell migration [GO:0030335]; signal transduction [GO:0007165]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	hyaluronic acid binding [GO:0005540]
d3wwke__d1c3ab___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	regulation of cytokine activity [GO:0060300]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d3wwke__d2py2a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	metal ion binding [GO:0046872]	regulation of cytokine activity [GO:0060300]		extracellular region [GO:0005576]		metal ion binding [GO:0046872]; toxin activity [GO:0090729]	metal ion binding [GO:0046872]
d3wwkf__d1bcpc2__1	Metazoa		Chordata	Proteobacteria	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; toxin activity [GO:0090729]	regulation of cytokine activity [GO:0060300]		extracellular region [GO:0005576]	extracellular region [GO:0005576]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d3wwkh__d1uosa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	regulation of cytokine activity [GO:0060300]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	toxin activity [GO:0090729]
d3wwki__d2msbb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	regulation of cytokine activity [GO:0060300]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	extracellular region [GO:0005576]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d3wwkl__d5f2qb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; regulation of cytokine activity [GO:0060300]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; negative regulation of cell growth [GO:0030308]	regulation of cytokine activity [GO:0060300]	negative regulation of cell growth [GO:0030308]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3wwob__d1qiea___1	Viridiplantae	Metazoa	Streptophyta	Chordata	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]; acetylcholinesterase activity [GO:0003990]; acetylcholine catabolic process in synaptic cleft [GO:0001507]		acetylcholine catabolic process in synaptic cleft [GO:0001507]		anchored component of membrane [GO:0031225]; cell junction [GO:0030054]; plasma membrane [GO:0005886]; synaptic cleft [GO:0043083]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	acetylcholinesterase activity [GO:0003990]
d3wwpa1_d1gxs.1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	hydroxymandelonitrile lyase activity [GO:0050419]					lyase activity [GO:0016829]; metal ion binding [GO:0046872]	hydroxymandelonitrile lyase activity [GO:0050419]
d3wwpa1_d5kbyc2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]		apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d3wwpr1_d1ek2a2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]		cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; epoxide metabolic process [GO:0097176]; inflammatory response [GO:0006954]; linoleic acid metabolic process [GO:0043651]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood pressure [GO:0045777]; positive regulation of gene expression [GO:0010628]; prostaglandin production involved in inflammatory response [GO:0002539]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; stilbene catabolic process [GO:0046272]		cytosol [GO:0005829]; peroxisome [GO:0005777]	lyase activity [GO:0016829]; metal ion binding [GO:0046872]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]
d3wwqa__d4rmab1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; astral microtubule organization [GO:0030953]; axon guidance [GO:0007411]; cellular protein-containing complex localization [GO:0034629]; cellular response to cAMP [GO:0071320]; cortical microtubule organization [GO:0043622]; cytoskeletal anchoring at plasma membrane [GO:0007016]; establishment of centrosome localization [GO:0051660]; establishment of endothelial barrier [GO:0061028]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; filopodium assembly [GO:0046847]; intestinal D-glucose absorption [GO:0001951]; leukocyte cell-cell adhesion [GO:0007159]; membrane to membrane docking [GO:0022614]; microvillus assembly [GO:0030033]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of interleukin-2 secretion [GO:1900041]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to early endosome [GO:1902966]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; protein localization to cell cortex [GO:0072697]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; regulation of cell shape [GO:0008360]; regulation of microvillus length [GO:0032532]; regulation of organelle assembly [GO:1902115]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; terminal web assembly [GO:1902896]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	actin cytoskeleton [GO:0015629]; actin filament [GO:0005884]; apical part of cell [GO:0045177]; apical plasma membrane [GO:0016324]; astrocyte projection [GO:0097449]; basolateral plasma membrane [GO:0016323]; brush border [GO:0005903]; cell [GO:0005623]; cell body [GO:0044297]; cell periphery [GO:0071944]; cell projection [GO:0042995]; cell tip [GO:0051286]; ciliary basal body [GO:0036064]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytoplasmic side of apical plasma membrane [GO:0098592]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; fibrillar center [GO:0001650]; filopodium [GO:0030175]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; invadopodium [GO:0071437]; membrane [GO:0016020]; microspike [GO:0044393]; microvillus [GO:0005902]; microvillus membrane [GO:0031528]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; plasma membrane raft [GO:0044853]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; ruffle membrane [GO:0032587]; Schwann cell microvillus [GO:0097454]; T-tubule [GO:0030315]; uropod [GO:0001931]; vesicle [GO:0031982]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; cell adhesion molecule binding [GO:0050839]; disordered domain specific binding [GO:0097718]; identical protein binding [GO:0042802]; microtubule binding [GO:0008017]; protein C-terminus binding [GO:0008022]; protein domain specific binding [GO:0019904]; protein kinase A binding [GO:0051018]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase A regulatory subunit binding [GO:0034237]; RNA binding [GO:0003723]; S100 protein binding [GO:0044548]
d3wwqd__d5aekl___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]; enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of action potential [GO:0045759]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; PML body organization [GO:0030578]; positive regulation of ATPase-coupled calcium transmembrane transporter activity [GO:1901896]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein complex assembly [GO:0031334]; protein localization to nuclear pore [GO:0090204]; protein stabilization [GO:0050821]; protein sumoylation [GO:0016925]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; regulation of protein localization [GO:0032880]; roof of mouth development [GO:0060021]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytosol [GO:0005829]; dendrite [GO:0030425]; fibrillar center [GO:0001650]; heterochromatin [GO:0000792]; nuclear body [GO:0016604]; nuclear envelope [GO:0005635]; nuclear membrane [GO:0031965]; nuclear pore [GO:0005643]; nuclear speck [GO:0016607]; nuclear stress granule [GO:0097165]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; SUMO activating enzyme complex [GO:0031510]; synapse [GO:0045202]; XY body [GO:0001741]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	enzyme binding [GO:0019899]; glucocorticoid receptor binding [GO:0035259]; potassium channel regulator activity [GO:0015459]; protein binding, bridging [GO:0030674]; protein C-terminus binding [GO:0008022]; protein tag [GO:0031386]; RNA binding [GO:0003723]; small protein activating enzyme binding [GO:0044388]; transcription corepressor binding [GO:0001222]; transcription factor binding [GO:0008134]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]
d3wwqe__d5chfc1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3wx5b__d1oa2c___1		Fungi		Ascomycota	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	cellulase activity [GO:0008810]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]	cellulase activity [GO:0008810]
d3wx8a__d3ztqg___1	Metazoa		Arthropoda	Aquificae	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nuclear microtubule [GO:0005880]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; nucleoside diphosphate kinase activity [GO:0004550]; adherens junction organization [GO:0034332]; CTP biosynthetic process [GO:0006241]; epithelial cell migration, open tracheal system [GO:0007427]; establishment or maintenance of polarity of follicular epithelium [GO:0016334]; GTP biosynthetic process [GO:0006183]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide metabolic process [GO:0009117]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of tube architecture, open tracheal system [GO:0035152]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	adherens junction organization [GO:0034332]; CTP biosynthetic process [GO:0006241]; epithelial cell migration, open tracheal system [GO:0007427]; establishment or maintenance of polarity of follicular epithelium [GO:0016334]; GTP biosynthetic process [GO:0006183]; microtubule-based process [GO:0007017]; mitotic cell cycle [GO:0000278]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide metabolic process [GO:0009117]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; regulation of tube architecture, open tracheal system [GO:0035152]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; microtubule [GO:0005874]; nuclear microtubule [GO:0005880]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3wxcb__d4axhb1__1			Proteobacteria	Proteobacteria	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]				beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]
d3wxgc__d4zrkb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d3wxgf__d5dpta___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cell body [GO:0044297]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendrite membrane [GO:0032590]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; intracellular [GO:0005622]; microtubule [GO:0005874]; beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; Tat protein binding [GO:0030957]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; cell body [GO:0044297]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dendrite membrane [GO:0032590]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; intracellular [GO:0005622]; microtubule [GO:0005874]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	beta-tubulin binding [GO:0048487]; GABA receptor binding [GO:0050811]; microtubule binding [GO:0008017]; Tat protein binding [GO:0030957]; ubiquitin protein ligase binding [GO:0031625]
d3wxia2_d2aa4a2__1				Proteobacteria	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	ATP binding [GO:0005524]; N-acylmannosamine kinase activity [GO:0009384]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cellular response to DNA damage stimulus [GO:0006974]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]			glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; N-acylmannosamine kinase activity [GO:0009384]; zinc ion binding [GO:0008270]
d3wxib1_d3bf3e1__1				Thermotogae	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d3wxib2_d4pkhf2__1		Metazoa		Chordata	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3wxja2_d2w41b1__1				Apicomplexa	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	mitochondrion [GO:0005739]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate biosynthetic process [GO:0046167]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]; triglyceride metabolic process [GO:0006641]		mitochondrion [GO:0005739]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]
d3wxjc2_d4cd3a1__1		Metazoa		Chordata	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adenosine-diphosphatase activity [GO:0043262]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]		cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	adenosine-diphosphatase activity [GO:0043262]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]
d3wxjd1_d3fe1b1__1		Metazoa		Chordata	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	blood microparticle [GO:0072562]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; neutrophil degranulation [GO:0043312]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; neutrophil degranulation [GO:0043312]; protein refolding [GO:0042026]; response to unfolded protein [GO:0006986]; vesicle-mediated transport [GO:0016192]		blood microparticle [GO:0072562]; centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d3wxka1_d2gtdd2__1				Thermotogae	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d3wxka2_d3bexe1__1				Thermotogae	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; pantothenate kinase activity [GO:0004594]
d3wxkb1_d5aqna2__1		Metazoa		Chordata	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3wxkc1_d4h5wb1__1		Metazoa		Chordata	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to starvation [GO:0009267]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; cytokine-mediated signaling pathway [GO:0019221]; late endosomal microautophagy [GO:0061738]; membrane organization [GO:0061024]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of supramolecular fiber organization [GO:1902904]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotransmitter secretion [GO:0007269]; neutrophil degranulation [GO:0043312]; protein folding [GO:0006457]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; regulation of cellular response to heat [GO:1900034]; regulation of mRNA stability [GO:0043488]; regulation of protein complex assembly [GO:0043254]; regulation of protein complex stability [GO:0061635]; regulation of protein import [GO:1904589]; regulation of protein stability [GO:0031647]; response to unfolded protein [GO:0006986]; slow axonal transport [GO:1990832]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]		autophagosome [GO:0005776]; axon [GO:0030424]; blood microparticle [GO:0072562]; chaperone complex [GO:0101031]; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [GO:0061202]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; focal adhesion [GO:0005925]; lumenal side of lysosomal membrane [GO:0098575]; lysosomal lumen [GO:0043202]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; secretory granule lumen [GO:0034774]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; C3HC4-type RING finger domain binding [GO:0055131]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; clathrin-uncoating ATPase activity [GO:1990833]; enzyme binding [GO:0019899]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; MHC class II protein complex binding [GO:0023026]; misfolded protein binding [GO:0051787]; protein binding, bridging [GO:0030674]; protein folding chaperone [GO:0044183]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d3wxkc2_d2a41a2__1		Metazoa		Chordata	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]; apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]		extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]
d3wxkd1_d1lcub1__1		Metazoa		Chordata	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3wxla1_d4jhdd1__1		Metazoa		Arthropoda	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]		actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]
d3wxlb1_d4czha1__1				Proteobacteria	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]		cytoplasm [GO:0005737]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]
d3wxlb2_d2qwpa2__1		Metazoa		Chordata	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]		autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d3wxlc1_d5aqoa2__1		Metazoa		Chordata	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d3wxld1_d3hbta2__1		Metazoa		Chordata	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate metabolic process [GO:0006072]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]		actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	glycerol kinase activity [GO:0004370]; nucleotide binding [GO:0000166]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d3wxma2_d3i1fa2__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d3wxma2_d4j0qe2__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3wxma3_d1ob2a2__1			Crenarchaeota	Proteobacteria	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; response to antibiotic [GO:0046677]; translational elongation [GO:0006414]		response to antibiotic [GO:0046677]; translational elongation [GO:0006414]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; plasma membrane [GO:0005886]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3wxmc2_d1qvgb___1			Crenarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	ribosome [GO:0005840]; large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]; translation [GO:0006412]		translation [GO:0006412]	cytoplasm [GO:0005737]	ribosome [GO:0005840]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	large ribosomal subunit rRNA binding [GO:0070180]; structural constituent of ribosome [GO:0003735]; zinc ion binding [GO:0008270]
d3wxme1_d2hv8b___1		Metazoa	Crenarchaeota	Chordata	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	axon [GO:0030424]; cell [GO:0005623]; centriolar satellite [GO:0034451]; cleavage furrow [GO:0032154]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; multivesicular body [GO:0005771]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; postsynaptic recycling endosome [GO:0098837]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; Schaffer collateral - CA1 synapse [GO:0098685]; spindle pole [GO:0000922]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133]; vesicle [GO:0031982]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; microtubule binding [GO:0008017]; myosin V binding [GO:0031489]; syntaxin binding [GO:0019905]; amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; plasma membrane to endosome transport [GO:0048227]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-translational protein modification [GO:0043687]; protein localization to plasma membrane [GO:0072659]; Rab protein signal transduction [GO:0032482]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; renal water homeostasis [GO:0003091]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003]		amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; plasma membrane to endosome transport [GO:0048227]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-translational protein modification [GO:0043687]; protein localization to plasma membrane [GO:0072659]; Rab protein signal transduction [GO:0032482]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; renal water homeostasis [GO:0003091]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003]	cytoplasm [GO:0005737]	axon [GO:0030424]; cell [GO:0005623]; centriolar satellite [GO:0034451]; cleavage furrow [GO:0032154]; cytoplasmic vesicle [GO:0031410]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; multivesicular body [GO:0005771]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; postsynaptic recycling endosome [GO:0098837]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; recycling endosome membrane [GO:0055038]; Schaffer collateral - CA1 synapse [GO:0098685]; spindle pole [GO:0000922]; trans-Golgi network [GO:0005802]; transport vesicle [GO:0030133]; vesicle [GO:0031982]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; microtubule binding [GO:0008017]; myosin V binding [GO:0031489]; syntaxin binding [GO:0019905]
d3wxmg2_d1ob5c1__1			Crenarchaeota	Deinococcus-Thermus	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]			cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d3wxmg2_d2qozd1__1			Crenarchaeota		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	
d3wxmg3_d4m0lb3__1			Crenarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]		formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d3wxr1__d4qz0q___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3wxrb__d1vsy1___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]		cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]		endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	
d3wxrg1_d1ai4.1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]; antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	antibiotic biosynthetic process [GO:0017000]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	periplasmic space [GO:0042597]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	metal ion binding [GO:0046872]; penicillin amidase activity [GO:0008953]
d3wxri__d5l64k___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3wxrt__d3sdkm___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3wxrv__d4qwrq___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3wxry__d5ltto___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d3wxsa__d4elaa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]			cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]		
d3wxta__d1owya___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3wxwh__d3t4yb1__1	Metazoa		Chordata		integral component of membrane [GO:0016021]; intrinsic component of plasma membrane [GO:0031226]; plasma membrane [GO:0005886]; adipokinetic hormone receptor activity [GO:0097003]; adiponectin binding [GO:0055100]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; signaling receptor activity [GO:0038023]; adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; female pregnancy [GO:0007565]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; negative regulation of cell growth [GO:0030308]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of glucose import [GO:0046326]; regulation of fatty acid biosynthetic process [GO:0042304]; response to nutrient [GO:0007584]; vascular wound healing [GO:0061042]		adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; female pregnancy [GO:0007565]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; negative regulation of cell growth [GO:0030308]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of glucose import [GO:0046326]; regulation of fatty acid biosynthetic process [GO:0042304]; response to nutrient [GO:0007584]; vascular wound healing [GO:0061042]		integral component of membrane [GO:0016021]; intrinsic component of plasma membrane [GO:0031226]; plasma membrane [GO:0005886]		adipokinetic hormone receptor activity [GO:0097003]; adiponectin binding [GO:0055100]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; signaling receptor activity [GO:0038023]	
d3wyhb__d4i7ka1__1	Metazoa		Chordata		extracellular region [GO:0005576]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	extracellular region [GO:0005576]	host cell cytoplasm [GO:0030430]	lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3wyka__d1u6za1__1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	plasma membrane [GO:0005886]; exopolyphosphatase activity [GO:0004309]; identical protein binding [GO:0042802]; phosphorus metabolic process [GO:0006793]; polyphosphate catabolic process [GO:0006798]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	phosphorus metabolic process [GO:0006793]; polyphosphate catabolic process [GO:0006798]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	plasma membrane [GO:0005886]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	exopolyphosphatase activity [GO:0004309]; identical protein binding [GO:0042802]
d3wylb__d3itua___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]
d3wylb__d3n3za___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3wymb__d2cqzd___1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	5'-deoxynucleotidase activity [GO:0002953]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]		cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]		3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	5'-deoxynucleotidase activity [GO:0002953]
d3wynb__d7yasa___1		Viridiplantae	Actinobacteria	Streptophyta	metal ion binding [GO:0046872]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]					metal ion binding [GO:0046872]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]
d3wypb__d2mf6b1__1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3wypc__d5csea1__1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3wyqa__d1wbif___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]; biotin transport [GO:0015878]		biotin transport [GO:0015878]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3wyra1_d3zdxl1__1	Metazoa	Metazoa	Chordata	Chordata	early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; MHC class Ib receptor activity [GO:0032394]; transmembrane signaling receptor activity [GO:0004888]; cellular defense response [GO:0006968]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; positive regulation of cellular senescence [GO:2000774]; positive regulation of natural killer cell cytokine production [GO:0002729]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	cellular defense response [GO:0006968]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; positive regulation of cellular senescence [GO:2000774]; positive regulation of natural killer cell cytokine production [GO:0002729]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]	early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]	MHC class Ib receptor activity [GO:0032394]; transmembrane signaling receptor activity [GO:0004888]	extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3wyra2_d5uy3b1__1	Metazoa		Chordata		early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; MHC class Ib receptor activity [GO:0032394]; transmembrane signaling receptor activity [GO:0004888]; cellular defense response [GO:0006968]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; positive regulation of cellular senescence [GO:2000774]; positive regulation of natural killer cell cytokine production [GO:0002729]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]		cellular defense response [GO:0006968]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; positive regulation of cellular senescence [GO:2000774]; positive regulation of natural killer cell cytokine production [GO:0002729]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]		early endosome membrane [GO:0031901]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]		MHC class Ib receptor activity [GO:0032394]; transmembrane signaling receptor activity [GO:0004888]	
d3wywa1_d2rm6a1__1	Metazoa		Arthropoda		transferase activity [GO:0016740]	glycosome [GO:0020015]; glutathione peroxidase activity [GO:0004602]; response to oxidative stress [GO:0006979]		response to oxidative stress [GO:0006979]		glycosome [GO:0020015]	transferase activity [GO:0016740]	glutathione peroxidase activity [GO:0004602]
d3wywa2_d5a5ki2__1	Metazoa	Viridiplantae	Arthropoda	Streptophyta	transferase activity [GO:0016740]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]		apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	transferase activity [GO:0016740]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d3wywa2_d5echf2__1	Metazoa	Viridiplantae	Arthropoda	Streptophyta	transferase activity [GO:0016740]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]		glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]		apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	transferase activity [GO:0016740]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d3wywb1_d1uula___1	Metazoa		Arthropoda		transferase activity [GO:0016740]						transferase activity [GO:0016740]	
d3wywb2_d14gsa1__1	Metazoa	Metazoa	Arthropoda	Chordata	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]; dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]; animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		animal organ regeneration [GO:0031100]; cellular response to cell-matrix adhesion [GO:0071460]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; central nervous system development [GO:0007417]; common myeloid progenitor cell proliferation [GO:0035726]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of leukocyte proliferation [GO:0070664]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neutrophil degranulation [GO:0043312]; nitric oxide storage [GO:0035732]; oligodendrocyte development [GO:0014003]; positive regulation of superoxide anion generation [GO:0032930]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of stress-activated MAPK cascade [GO:0032872]; response to amino acid [GO:0043200]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to L-ascorbic acid [GO:0033591]; response to reactive oxygen species [GO:0000302]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; TRAF2-GSTP1 complex [GO:0097057]; vesicle [GO:0031982]	transferase activity [GO:0016740]	dinitrosyl-iron complex binding [GO:0035731]; drug binding [GO:0008144]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; JUN kinase binding [GO:0008432]; kinase regulator activity [GO:0019207]; nitric oxide binding [GO:0070026]; S-nitrosoglutathione binding [GO:0035730]
d3wz1a__d1v6od___1		Viridiplantae	Proteobacteria	Streptophyta	beta-agarase activity [GO:0033916]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]				beta-agarase activity [GO:0033916]; carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3wz6a__d3kf1a___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]						aspartic-type endopeptidase activity [GO:0004190]	
d3wz7a__d4hdbb___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3wz8a__d3nu6b___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3wzqc1_d1n9yd___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3wzva1_d3mbcb___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]		3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; metal ion binding [GO:0046872]
d3wzxa1_d2uxqc___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; leucine biosynthetic process [GO:0009098]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	leucine biosynthetic process [GO:0009098]	isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]		3-isopropylmalate dehydrogenase activity [GO:0003862]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d3x00b1_d1slfd___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3x00d1_d5irua___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]; antibacterial humoral response [GO:0019731]		antibacterial humoral response [GO:0019731]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d3x0wa1_d5dpwg___1	Metazoa	Metazoa	Chordata	Chordata	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]; microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; nucleolus [GO:0005730]; metal ion binding [GO:0046872]; autophagy [GO:0006914]; intracellular signal transduction [GO:0035556]; lysosome localization [GO:0032418]; positive regulation of bone resorption [GO:0045780]; positive regulation of ruffle assembly [GO:1900029]; protein transport [GO:0015031]	autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]	autophagy [GO:0006914]; intracellular signal transduction [GO:0035556]; lysosome localization [GO:0032418]; positive regulation of bone resorption [GO:0045780]; positive regulation of ruffle assembly [GO:1900029]; protein transport [GO:0015031]	autophagosome [GO:0005776]; autophagosome membrane [GO:0000421]; axoneme [GO:0005930]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; intracellular [GO:0005622]; intracellular membrane-bounded organelle [GO:0043231]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; organelle membrane [GO:0031090]	endosome membrane [GO:0010008]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; nucleolus [GO:0005730]	microtubule binding [GO:0008017]; ubiquitin protein ligase binding [GO:0031625]	metal ion binding [GO:0046872]
d3x1ja__d1jeeb2__1		Fungi	Proteobacteria	Ascomycota	cytoplasm [GO:0005737]; [citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfur amino acid metabolic process [GO:0000096]	coenzyme A biosynthetic process [GO:0015937]	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]; sulfur amino acid metabolic process [GO:0000096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	[citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; sulfate adenylyltransferase (ATP) activity [GO:0004781]
d3x1jb__d1n78a2__1			Proteobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; [citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]; glutamyl-tRNA aminoacylation [GO:0006424]	coenzyme A biosynthetic process [GO:0015937]	glutamyl-tRNA aminoacylation [GO:0006424]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	[citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; glutamate-tRNA ligase activity [GO:0004818]; tRNA binding [GO:0000049]; zinc ion binding [GO:0008270]
d3x1ka__d3mmxb___1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; [citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; NAD biosynthetic process [GO:0009435]	coenzyme A biosynthetic process [GO:0015937]	NAD biosynthetic process [GO:0009435]	cytoplasm [GO:0005737]		[citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]
d3x1kb__d3dv2c___1			Proteobacteria		cytoplasm [GO:0005737]; [citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]		coenzyme A biosynthetic process [GO:0015937]		cytoplasm [GO:0005737]		[citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	
d3x1ma__d3otwe___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; [citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	[citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d3x1mc__d5jbnb___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; [citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]; coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]	coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	[citrate (pro-3S)-lyase] ligase activity [GO:0008771]; ATP binding [GO:0005524]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; pantetheine-phosphate adenylyltransferase activity [GO:0004595]
d3x20b__d3a8gb___1			Actinobacteria	Actinobacteria	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d3x21a__d4qlxb___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; 6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]; 2,4,6-trinitrotoluene catabolic process [GO:0046256]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	2,4,6-trinitrotoluene catabolic process [GO:0046256]		cytosol [GO:0005829]; membrane [GO:0016020]		6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3x21b__d1v5ya___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; 6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]; 2,4,6-trinitrotoluene catabolic process [GO:0046256]	oxidoreductase activity [GO:0016491]; bioluminescence [GO:0008218]	2,4,6-trinitrotoluene catabolic process [GO:0046256]	bioluminescence [GO:0008218]	cytosol [GO:0005829]; membrane [GO:0016020]		6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]	oxidoreductase activity [GO:0016491]
d3x21g__d1necb___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; membrane [GO:0016020]; 6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]; 2,4,6-trinitrotoluene catabolic process [GO:0046256]	oxidoreductase activity [GO:0016491]	2,4,6-trinitrotoluene catabolic process [GO:0046256]		cytosol [GO:0005829]; membrane [GO:0016020]		6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]	oxidoreductase activity [GO:0016491]
d3x21h__d5heib1__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; membrane [GO:0016020]; 6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]; 2,4,6-trinitrotoluene catabolic process [GO:0046256]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	2,4,6-trinitrotoluene catabolic process [GO:0046256]		cytosol [GO:0005829]; membrane [GO:0016020]		6,7-dihydropteridine reductase activity [GO:0004155]; FMN binding [GO:0010181]; identical protein binding [GO:0042802]; NAD(P)H nitroreductase activity [GO:0018545]; oxidoreductase activity [GO:0016491]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d3x26b__d2dppb___1			Actinobacteria	Firmicutes	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]			indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]
d3x28b__d3qygf___1			Actinobacteria		indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]; nitrogen compound metabolic process [GO:0006807]		nitrogen compound metabolic process [GO:0006807]				indole-3-acetonitrile nitrile hydratase activity [GO:0080109]; transition metal ion binding [GO:0046914]	
d3x2qo2_d1joia___1	Metazoa		Chordata	Proteobacteria	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d3x33a__d1b5ma___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	oxidation-reduction process [GO:0055114]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial outer membrane [GO:0005741]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [GO:0045153]; enzyme activator activity [GO:0008047]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3x34a__d1m59a___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3x3gl1_d4ynyd2__1												
d3x3hc__d4oyyd___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]				extracellular region [GO:0005576]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	cutinase activity [GO:0050525]
d3x3he__d1wpxa___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; fungal-type vacuole [GO:0000324]; fungal-type vacuole lumen [GO:0000328]; serine-type carboxypeptidase activity [GO:0004185]; macroautophagy [GO:0016236]; phytochelatin biosynthetic process [GO:0046938]; protein catabolic process in the vacuole [GO:0007039]; proteolysis involved in cellular protein catabolic process [GO:0051603]; zymogen activation [GO:0031638]		macroautophagy [GO:0016236]; phytochelatin biosynthetic process [GO:0046938]; protein catabolic process in the vacuole [GO:0007039]; proteolysis involved in cellular protein catabolic process [GO:0051603]; zymogen activation [GO:0031638]		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; fungal-type vacuole [GO:0000324]; fungal-type vacuole lumen [GO:0000328]	aliphatic (S)-hydroxynitrile lyase activity [GO:0052891]; aromatic (S)-hydroxynitrile lyase activity [GO:0052892]	serine-type carboxypeptidase activity [GO:0004185]
d3x3oa__d1ly0a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]			cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]		
d3x3ra__d4h8tb___1	Viridiplantae		Streptophyta		cytoplasmic vesicle [GO:0031410]				cytoplasmic vesicle [GO:0031410]			
d3x3sa__d5fgxa___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]			cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]		
d3x3ua__d3ncrc1__1			Proteobacteria	Euryarchaeota	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; metal ion binding [GO:0046872]; protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]	protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	regulation of nitrogen utilization [GO:0006808]	cytoplasm [GO:0005737]		copper ion binding [GO:0005507]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]
d3x3uc__d4yb5c2__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; metal ion binding [GO:0046872]; protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]; histidine biosynthetic process [GO:0000105]	protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	histidine biosynthetic process [GO:0000105]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	copper ion binding [GO:0005507]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; ATP phosphoribosyltransferase activity [GO:0003879]; magnesium ion binding [GO:0000287]
d3x43d__d1wdwd___1			Actinobacteria	Euryarchaeota	cysteine synthase activity [GO:0004124]; antibiotic biosynthetic process [GO:0017000]; cysteine biosynthetic process from serine [GO:0006535]	tryptophan synthase activity [GO:0004834]	antibiotic biosynthetic process [GO:0017000]; cysteine biosynthetic process from serine [GO:0006535]				cysteine synthase activity [GO:0004124]	tryptophan synthase activity [GO:0004834]
d3xima__d1xyla___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d3xima__d4k1ga___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]; base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	D-xylose metabolic process [GO:0042732]	base-excision repair [GO:0006284]; non-recombinational repair [GO:0000726]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	deoxyribonuclease IV (phage-T4-induced) activity [GO:0008833]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; phosphoric diester hydrolase activity [GO:0008081]; zinc ion binding [GO:0008270]
d3ximc__d5nh6a___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d3ximd__d1bxcd___1			Actinobacteria	Deinococcus-Thermus	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d3xina__d1a0db___1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d3xina__d5nh4a___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d3xinc__d7ximc___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d3xind__d4ximc___1			Actinobacteria	Actinobacteria	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	D-xylose metabolic process [GO:0042732]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]
d3xind__d5nh5c___1		Fungi	Actinobacteria	Chytridiomycota	cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]; D-xylose metabolic process [GO:0042732]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]; xylose catabolic process to ethanol [GO:0044577]	D-xylose metabolic process [GO:0042732]	xylose catabolic process to ethanol [GO:0044577]	cytoplasm [GO:0005737]		magnesium ion binding [GO:0000287]; xylose isomerase activity [GO:0009045]	metal ion binding [GO:0046872]; xylose isomerase activity [GO:0009045]
d3ygsp1_d1d2zd___1	Metazoa	Metazoa	Chordata	Arthropoda	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; negative regulation of G0 to G1 transition [GO:0070317]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; neutrophil degranulation [GO:0043312]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	antifungal innate immune response [GO:0061760]; apoptotic process [GO:0006915]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal/ventral asymmetry [GO:0048262]; dorsal/ventral pattern formation [GO:0009953]; hemocyte proliferation [GO:0035172]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; larval somatic muscle development [GO:0007526]; positive regulation of antifungal peptide production [GO:0002804]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Toll signaling pathway [GO:0008063]; zygotic specification of dorsal/ventral axis [GO:0007352]	apoptosome [GO:0043293]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	ATP binding [GO:0005524]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]
d3ypib__d3uwub___1	Fungi		Ascomycota	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d3zbta1_d1qfza1__1		Viridiplantae	Cyanobacteria	Streptophyta	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	photosynthesis [GO:0015979]	phycobilisome [GO:0030089]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]
d3zbta1_d4e0fa1__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	riboflavin binding [GO:1902444]; riboflavin synthase activity [GO:0004746]; protein homotrimerization [GO:0070207]; riboflavin biosynthetic process [GO:0009231]	oxidation-reduction process [GO:0055114]	protein homotrimerization [GO:0070207]; riboflavin biosynthetic process [GO:0009231]	phycobilisome [GO:0030089]		ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	riboflavin binding [GO:1902444]; riboflavin synthase activity [GO:0004746]
d3zbta2_d4yala3__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]; carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	oxidation-reduction process [GO:0055114]	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of cholesterol metabolic process [GO:0090181]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	phycobilisome [GO:0030089]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; mitochondrion [GO:0005739]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; electron transfer activity [GO:0009055]; enzyme binding [GO:0019899]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; hydrolase activity [GO:0016787]; iron-cytochrome-c reductase activity [GO:0047726]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric oxide dioxygenase activity [GO:0008941]; oxidoreductase activity [GO:0016491]
d3zbua2_d4k1xb2__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d3zbua2_d5gv8a2__1		Metazoa	Cyanobacteria	Chordata	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; cholesterol biosynthetic process [GO:0006695]	oxidation-reduction process [GO:0055114]	cholesterol biosynthetic process [GO:0006695]	phycobilisome [GO:0030089]	endoplasmic reticulum membrane [GO:0005789]; mitochondrial outer membrane [GO:0005741]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d3zbva__d1eiea___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; nucleolus [GO:0005730]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; ribonuclease activity [GO:0004540]; cellular response to glucose stimulus [GO:0071333]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	cellular response to glucose stimulus [GO:0071333]		cell [GO:0005623]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; nucleolus [GO:0005730]	extracellular region [GO:0005576]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; ribonuclease activity [GO:0004540]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d3zc3b1_d4g6ic1__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	riboflavin binding [GO:1902444]; riboflavin synthase activity [GO:0004746]; protein homotrimerization [GO:0070207]; riboflavin biosynthetic process [GO:0009231]	oxidation-reduction process [GO:0055114]	protein homotrimerization [GO:0070207]; riboflavin biosynthetic process [GO:0009231]	phycobilisome [GO:0030089]		ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	riboflavin binding [GO:1902444]; riboflavin synthase activity [GO:0004746]
d3zc3b2_d2vyqa2__1			Cyanobacteria	Cyanobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	phycobilisome [GO:0030089]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d3zc9a__d1eyla___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	endopeptidase inhibitor activity [GO:0004866]	serine-type endopeptidase inhibitor activity [GO:0004867]					endopeptidase inhibitor activity [GO:0004866]	serine-type endopeptidase inhibitor activity [GO:0004867]
d3zcfa__d1ppjq1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; catalytic activity [GO:0003824]; metal ion binding [GO:0046872]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]; metal ion binding [GO:0046872]
d3zcfa__d2n18c___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3zcfc__d1u74d___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3zcfd__d2pccb___1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3zcga__d1cpfa___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	chloroplast [GO:0009507]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3zdgc__d2c9tj___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d3zdmc__d4hcpb1__1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]; cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]		cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]		polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]	
d3zdmf__d5lrwb1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]; polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]; cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; posttranslational protein targeting to endoplasmic reticulum membrane [GO:0006620]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein insertion into ER membrane [GO:0045048]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; energy homeostasis [GO:0097009]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; fat pad development [GO:0060613]; female gonad development [GO:0008585]; female meiosis I [GO:0007144]; global genome nucleotide-excision repair [GO:0070911]; hypothalamus gonadotrophin-releasing hormone neuron development [GO:0021888]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; male meiosis I [GO:0007141]; membrane organization [GO:0061024]; mitochondrion transport along microtubule [GO:0047497]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron projection morphogenesis [GO:0048812]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein monoubiquitination [GO:1902527]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mRNA stability [GO:0043488]; regulation of neuron death [GO:1901214]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; seminiferous tubule development [GO:0072520]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome complex [GO:0000502]; TRC complex [GO:0072380]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	polyubiquitin modification-dependent protein binding [GO:0031593]; proteasome binding [GO:0070628]; ubiquitin binding [GO:0043130]	protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3zdsb__d5buva1__1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]	L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]		protein-DNA complex [GO:0032993]		DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d3zdse__d1yfya1__1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]; 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]	L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]	protein-DNA complex [GO:0032993]		DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]
d3zdsf__d1zvfb2__1		Fungi	Proteobacteria	Ascomycota	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; 3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]; 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; quinolinate metabolic process [GO:0046874]; tryptophan catabolic process [GO:0006569]	L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; quinolinate metabolic process [GO:0046874]; tryptophan catabolic process [GO:0006569]	protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]
d3zdsf__d4luma1__1			Proteobacteria	Euryarchaeota	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]	DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]
d3zdsg__d2b9uc___1			Proteobacteria	Crenarchaeota	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; dTDP-rhamnose biosynthetic process [GO:0019305]	L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	dTDP-rhamnose biosynthetic process [GO:0019305]	protein-DNA complex [GO:0032993]		DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d3zdsj__d2phdd___1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]		protein-DNA complex [GO:0032993]		DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d3zdsk__d5fcca___1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]		L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]		protein-DNA complex [GO:0032993]		DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	
d3zdvb__d5a70c___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3zdwa2_d2iwka2__1			Firmicutes	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	membrane [GO:0016020]; periplasmic space [GO:0042597]; calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]; denitrification pathway [GO:0019333]	sporulation resulting in formation of a cellular spore [GO:0030435]	denitrification pathway [GO:0019333]	outer membrane-bounded periplasmic space [GO:0030288]	membrane [GO:0016020]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	calcium ion binding [GO:0005509]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; nitrous-oxide reductase activity [GO:0050304]
d3zdwa3_d5n8ga2__1			Firmicutes	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	sporulation resulting in formation of a cellular spore [GO:0030435]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d3zdxf1_d1ikfl2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	
d3zdxf2_d1lgva1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	
d3zdxl2_d3phoa1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]; extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; integrin-mediated signaling pathway [GO:0007229]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of leukocyte migration [GO:0002687]; regulation of megakaryocyte differentiation [GO:0045652]		blood microparticle [GO:0072562]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integrin complex [GO:0008305]; plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092]		extracellular matrix binding [GO:0050840]; fibrinogen binding [GO:0070051]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	
d3zeka__d1l98a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d3zf1a__d2qxxa___1				Actinobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d3zf3a__d1sjnc___1				Actinobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d3zfea__d5bnpc___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3zfeb__d5aooc___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell Golgi membrane [GO:0044178]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell Golgi membrane [GO:0044178]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d3zfec__d2vq0a1__1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	viral capsid [GO:0019028]; metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	metal ion binding [GO:0046872]; structural molecule activity [GO:0005198]
d3zfkb1_d4uhpa___1			Proteobacteria	Proteobacteria	extrachromosomal circular DNA [GO:0005727]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	toxic substance binding [GO:0015643]; bacteriocin immunity [GO:0030153]	cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; pathogenesis [GO:0009405]	bacteriocin immunity [GO:0030153]	extrachromosomal circular DNA [GO:0005727]		endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]	toxic substance binding [GO:0015643]
d3zfza1_d1iska___1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	response to antibiotic [GO:0046677]	steroid metabolic process [GO:0008202]	integral component of membrane [GO:0016021]		penicillin binding [GO:0008658]	steroid delta-isomerase activity [GO:0004769]
d3zfzb1_d4jf8a___1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	integral component of membrane [GO:0016021]; protein secretion by the type IV secretion system [GO:0030255]	response to antibiotic [GO:0046677]	protein secretion by the type IV secretion system [GO:0030255]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	penicillin binding [GO:0008658]	
d3zg0b1_d2f99a2__1			Firmicutes	Actinobacteria	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	intramolecular lyase activity [GO:0016872]; antibiotic biosynthetic process [GO:0017000]; daunorubicin biosynthetic process [GO:1901771]; doxorubicin metabolic process [GO:0044598]	response to antibiotic [GO:0046677]	antibiotic biosynthetic process [GO:0017000]; daunorubicin biosynthetic process [GO:1901771]; doxorubicin metabolic process [GO:0044598]	integral component of membrane [GO:0016021]		penicillin binding [GO:0008658]	intramolecular lyase activity [GO:0016872]
d3zgoc__d4k9oc2__1	Metazoa		Chordata	Proteobacteria	centriole [GO:0005814]; centrosome [GO:0005813]; chromatin silencing complex [GO:0005677]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glial cell projection [GO:0097386]; growth cone [GO:0030426]; juxtaparanode region of axon [GO:0044224]; lateral loop [GO:0043219]; meiotic spindle [GO:0072687]; microtubule [GO:0005874]; midbody [GO:0030496]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; myelin sheath [GO:0043209]; nuclear heterochromatin [GO:0005720]; nucleolus [GO:0005730]; nucleus [GO:0005634]; paranodal junction [GO:0033010]; paranode region of axon [GO:0033270]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; Schmidt-Lanterman incisure [GO:0043220]; spindle [GO:0005819]; chromatin binding [GO:0003682]; histone acetyltransferase binding [GO:0035035]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone deacetylase activity (H4-K16 specific) [GO:0046970]; NAD-dependent protein deacetylase activity [GO:0034979]; protein deacetylase activity [GO:0033558]; transcription factor binding [GO:0008134]; tubulin deacetylase activity [GO:0042903]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; cell division [GO:0051301]; cellular lipid catabolic process [GO:0044242]; cellular response to caloric restriction [GO:0061433]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to oxidative stress [GO:0034599]; chromatin silencing [GO:0006342]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at telomere [GO:0006348]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; innate immune response [GO:0045087]; meiotic cell cycle [GO:0051321]; myelination in peripheral nervous system [GO:0022011]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-lysine deacetylation [GO:0034983]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of cell division [GO:0051781]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]; protein kinase B signaling [GO:0043491]; regulation of cell cycle [GO:0051726]; regulation of exit from mitosis [GO:0007096]; regulation of myelination [GO:0031641]; regulation of phosphorylation [GO:0042325]; response to redox state [GO:0051775]; substantia nigra development [GO:0021762]; tubulin deacetylation [GO:0090042]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]; mandelate catabolic process [GO:0019596]	autophagy [GO:0006914]; cell division [GO:0051301]; cellular lipid catabolic process [GO:0044242]; cellular response to caloric restriction [GO:0061433]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to oxidative stress [GO:0034599]; chromatin silencing [GO:0006342]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at telomere [GO:0006348]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; innate immune response [GO:0045087]; meiotic cell cycle [GO:0051321]; myelination in peripheral nervous system [GO:0022011]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of defense response to bacterium [GO:1900425]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; peptidyl-lysine deacetylation [GO:0034983]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of cell division [GO:0051781]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of meiotic nuclear division [GO:0045836]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]; protein kinase B signaling [GO:0043491]; regulation of cell cycle [GO:0051726]; regulation of exit from mitosis [GO:0007096]; regulation of myelination [GO:0031641]; regulation of phosphorylation [GO:0042325]; response to redox state [GO:0051775]; substantia nigra development [GO:0021762]; tubulin deacetylation [GO:0090042]	mandelate catabolic process [GO:0019596]	centriole [GO:0005814]; centrosome [GO:0005813]; chromatin silencing complex [GO:0005677]; chromosome [GO:0005694]; chromosome, telomeric region [GO:0000781]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; glial cell projection [GO:0097386]; growth cone [GO:0030426]; juxtaparanode region of axon [GO:0044224]; lateral loop [GO:0043219]; meiotic spindle [GO:0072687]; microtubule [GO:0005874]; midbody [GO:0030496]; mitochondrion [GO:0005739]; mitotic spindle [GO:0072686]; myelin sheath [GO:0043209]; nuclear heterochromatin [GO:0005720]; nucleolus [GO:0005730]; nucleus [GO:0005634]; paranodal junction [GO:0033010]; paranode region of axon [GO:0033270]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; Schmidt-Lanterman incisure [GO:0043220]; spindle [GO:0005819]		chromatin binding [GO:0003682]; histone acetyltransferase binding [GO:0035035]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent histone deacetylase activity (H4-K16 specific) [GO:0046970]; NAD-dependent protein deacetylase activity [GO:0034979]; protein deacetylase activity [GO:0033558]; transcription factor binding [GO:0008134]; tubulin deacetylase activity [GO:0042903]; ubiquitin binding [GO:0043130]; zinc ion binding [GO:0008270]	benzoylformate decarboxylase activity [GO:0050695]; magnesium ion binding [GO:0000287]; thiamine pyrophosphate binding [GO:0030976]
d3zhcb__d2p77a___1			Proteobacteria	Deinococcus-Thermus		catalytic activity [GO:0003824]						catalytic activity [GO:0003824]
d3zhgc__d1v7pa___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; (1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	extracellular region [GO:0005576]; toxin activity [GO:0090729]	detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]		external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	extracellular region [GO:0005576]	(1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]	toxin activity [GO:0090729]
d3zhgd__d1dy0a___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; (1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	basement membrane [GO:0005604]; collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]	detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	basement membrane [GO:0005604]; collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	(1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]	extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d3zhkb1_d3v0vl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3zhla1_d1mclb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3zhla1_d2xa8l2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d3zhwa__d2v1ja___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen transport [GO:0015671]; response to hypoxia [GO:0001666]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]	oxygen transport [GO:0015671]; response to hypoxia [GO:0001666]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d3zhwb__d2uulb___1	Viridiplantae		Streptophyta		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen transport [GO:0015671]; response to hypoxia [GO:0001666]		oxygen transport [GO:0015671]; response to hypoxia [GO:0001666]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]	
d3zi6a__d4wf6a2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]		negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pathogenesis [GO:0009405]; positive regulation of apoptotic process in other organism [GO:0044533]; proteolysis [GO:0006508]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metallopeptidase activity [GO:0008237]; toxin activity [GO:0090729]
d3ziaa1_d2jdid2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3ziaa2_d1z2cc___1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cell cortex [GO:0005938]; cell division site [GO:0032153]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stereocilium [GO:0032420]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein kinase binding [GO:0019901]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; apical junction assembly [GO:0043297]; cell migration [GO:0016477]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; G protein-coupled receptor signaling pathway [GO:0007186]; mitotic cytokinesis [GO:0000281]; positive regulation of cell migration [GO:0030335]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of lipase activity [GO:0060193]; positive regulation of protein homooligomerization [GO:0032464]; positive regulation of stress fiber assembly [GO:0051496]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; skeletal muscle satellite cell migration [GO:1902766]; wound healing, spreading of cells [GO:0044319]	ATP synthesis coupled proton transport [GO:0015986]	actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; apical junction assembly [GO:0043297]; cell migration [GO:0016477]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; G protein-coupled receptor signaling pathway [GO:0007186]; mitotic cytokinesis [GO:0000281]; positive regulation of cell migration [GO:0030335]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of lipase activity [GO:0060193]; positive regulation of protein homooligomerization [GO:0032464]; positive regulation of stress fiber assembly [GO:0051496]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; skeletal muscle satellite cell migration [GO:1902766]; wound healing, spreading of cells [GO:0044319]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	cell cortex [GO:0005938]; cell division site [GO:0032153]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; stereocilium [GO:0032420]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein kinase binding [GO:0019901]
d3ziaa3_d3ssaa3__1	Fungi		Ascomycota	Euryarchaeota	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3ziac3_d2jizh3__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3ziad3_d5hkkd3__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3ziae1_d1nbmf2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3ziaf1_d3a5ck1__1	Fungi		Ascomycota	Deinococcus-Thermus	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]		hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3ziak1_d2jj2b1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3zial1_d3oeew1__1	Fungi	Fungi	Ascomycota	Ascomycota	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3ziam2_d2afkh___1	Fungi		Ascomycota		mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]		ATP synthesis coupled proton transport [GO:0015986]		mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]		hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	
d3ziao3_d2rkwb3__1	Fungi		Ascomycota	Euryarchaeota	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3ziap1_d1e1qb2__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3ziap2_d1u81a___1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cell [GO:0005623]; cell leading edge [GO:0031252]; COPI-coated vesicle [GO:0030137]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; late endosome [GO:0005770]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal membrane [GO:0005778]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; trans-Golgi network [GO:0005802]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; phospholipase D activator activity [GO:1990583]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; actin filament organization [GO:0007015]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular copper ion homeostasis [GO:0006878]; cellular response to virus [GO:0098586]; dendritic spine organization [GO:0097061]; Golgi to transport vesicle transport [GO:0055108]; interleukin-12-mediated signaling pathway [GO:0035722]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; lysosomal membrane organization [GO:0097212]; mitotic cleavage furrow ingression [GO:1990386]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of endocytosis [GO:0045807]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of late endosome to lysosome transport [GO:1902824]; positive regulation of protein secretion [GO:0050714]; positive regulation of sodium ion transmembrane transport [GO:1902307]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of defense response to virus by virus [GO:0050690]; regulation of phospholipid metabolic process [GO:1903725]; regulation of receptor internalization [GO:0002090]; synaptic vesicle budding [GO:0070142]; very-low-density lipoprotein particle assembly [GO:0034379]; vesicle-mediated transport [GO:0016192]	ATP synthesis coupled proton transport [GO:0015986]	actin filament organization [GO:0007015]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular copper ion homeostasis [GO:0006878]; cellular response to virus [GO:0098586]; dendritic spine organization [GO:0097061]; Golgi to transport vesicle transport [GO:0055108]; interleukin-12-mediated signaling pathway [GO:0035722]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; lysosomal membrane organization [GO:0097212]; mitotic cleavage furrow ingression [GO:1990386]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of endocytosis [GO:0045807]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of late endosome to lysosome transport [GO:1902824]; positive regulation of protein secretion [GO:0050714]; positive regulation of sodium ion transmembrane transport [GO:1902307]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of defense response to virus by virus [GO:0050690]; regulation of phospholipid metabolic process [GO:1903725]; regulation of receptor internalization [GO:0002090]; synaptic vesicle budding [GO:0070142]; very-low-density lipoprotein particle assembly [GO:0034379]; vesicle-mediated transport [GO:0016192]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	cell [GO:0005623]; cell leading edge [GO:0031252]; COPI-coated vesicle [GO:0030137]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; late endosome [GO:0005770]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal membrane [GO:0005778]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; trans-Golgi network [GO:0005802]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; phospholipase D activator activity [GO:1990583]; protein domain specific binding [GO:0019904]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d3ziap3_d5ik2a3__1	Fungi		Ascomycota	Firmicutes	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrion [GO:0005739]; hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase, central stalk [GO:0005756]; mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [GO:0000275]; mitochondrion [GO:0005739]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	hydrolase activity [GO:0016787]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d3zija__d5ijtf___1		Metazoa	Firmicutes	Chordata	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]; activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	cell redox homeostasis [GO:0045454]	activation of MAPK activity [GO:0000187]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; homeostasis of number of cells [GO:0048872]; hydrogen peroxide catabolic process [GO:0042744]; leukocyte activation [GO:0045321]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of blood coagulation [GO:0030194]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide metabolic process [GO:0010310]; removal of superoxide radicals [GO:0019430]; respiratory burst involved in inflammatory response [GO:0002536]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]; T cell proliferation [GO:0042098]; thymus development [GO:0048538]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	antioxidant activity [GO:0016209]; thioredoxin peroxidase activity [GO:0008379]
d3zitb__d2v41h___1		Metazoa	Firmicutes	Annelida	cell [GO:0005623]; electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	electron transfer activity [GO:0009055]; protein disulfide oxidoreductase activity [GO:0015035]	peroxiredoxin activity [GO:0051920]
d3ziwa2_d3muz21__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; toxin activity [GO:0090729]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]		lactose catabolic process [GO:0005990]	extracellular region [GO:0005576]	beta-galactosidase complex [GO:0009341]	toxin activity [GO:0090729]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d3ziwa2_d3x29b___1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; toxin activity [GO:0090729]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	toxin activity [GO:0090729]
d3ziwb2_d1ghom3__1			Firmicutes		extracellular region [GO:0005576]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		toxin activity [GO:0090729]	
d3zixa2_d2eica2__1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; toxin activity [GO:0090729]	extracellular region [GO:0005576]; galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	toxin activity [GO:0090729]	galactose oxidase activity [GO:0045480]; metal ion binding [GO:0046872]
d3zixb2_d1jz1p3__1			Firmicutes		extracellular region [GO:0005576]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		toxin activity [GO:0090729]	
d3zixd2_d3eb7b3__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]		toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d3zixe2_d1jyzj3__1			Firmicutes		extracellular region [GO:0005576]; toxin activity [GO:0090729]				extracellular region [GO:0005576]		toxin activity [GO:0090729]	
d3zixf2_d3hpnc___1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; toxin activity [GO:0090729]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; virus receptor activity [GO:0001618]; activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]		activation of GTPase activity [GO:0090630]; axial mesoderm formation [GO:0048320]; axon guidance [GO:0007411]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cAMP metabolic process [GO:0046058]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; ephrin receptor signaling pathway [GO:0048013]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; keratinocyte differentiation [GO:0030216]; lens fiber cell morphogenesis [GO:0070309]; mammary gland epithelial cell proliferation [GO:0033598]; multicellular organism development [GO:0007275]; negative regulation of angiogenesis [GO:0016525]; negative regulation of chemokine production [GO:0032682]; negative regulation of lymphangiogenesis [GO:1901491]; negative regulation of protein kinase B signaling [GO:0051898]; neural tube development [GO:0021915]; notochord cell development [GO:0060035]; notochord formation [GO:0014028]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; pericyte cell differentiation [GO:1904238]; positive regulation of bicellular tight junction assembly [GO:1903348]; positive regulation of protein localization to plasma membrane [GO:1903078]; post-anal tail morphogenesis [GO:0036342]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of lamellipodium assembly [GO:0010591]; response to growth factor [GO:0070848]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vasculogenesis [GO:0001570]	extracellular region [GO:0005576]	cell surface [GO:0009986]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; leading edge membrane [GO:0031256]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ruffle membrane [GO:0032587]; tight junction [GO:0070160]	toxin activity [GO:0090729]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; virus receptor activity [GO:0001618]
d3zjka__d3fj0a___1			Deinococcus-Thermus		beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]		cellulose catabolic process [GO:0030245]				beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	
d3zk5a__d4ruid1__1		Metazoa	Actinobacteria	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d3zk7a__d5ovwd___1			Firmicutes	Proteobacteria	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; cobalamin binding [GO:0031419]; cobalamin transport [GO:0015889]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	cobalamin transport [GO:0015889]	plasma membrane [GO:0005886]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	metal ion binding [GO:0046872]	cobalamin binding [GO:0031419]
d3zk8b__d5tcyb1__1			Firmicutes	Proteobacteria	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	metal ion binding [GO:0046872]; iron ion transport [GO:0006826]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	iron ion transport [GO:0006826]	plasma membrane [GO:0005886]		metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3zk9b__d5cx1m___1			Firmicutes	Proteobacteria	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	nitrogen fixation [GO:0009399]	plasma membrane [GO:0005886]	molybdenum-iron nitrogenase complex [GO:0016612]	metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d3zkaa__d5bvha___1			Firmicutes	Proteobacteria	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	molybdenum-iron nitrogenase complex [GO:0016612]; ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]; nitrogen fixation [GO:0009399]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	nitrogen fixation [GO:0009399]	plasma membrane [GO:0005886]	molybdenum-iron nitrogenase complex [GO:0016612]	metal ion binding [GO:0046872]	ATP binding [GO:0005524]; carbonyl sulfide nitrogenase activity [GO:0018697]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; nitrogenase activity [GO:0016163]
d3zkjf__d3wa0f1__1	Metazoa	Metazoa	Chordata	Chordata	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]; actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	adherens junction [GO:0005912]; apical part of cell [GO:0045177]; cell body [GO:0044297]; cleavage furrow [GO:0032154]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; early endosome [GO:0005769]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleolus [GO:0005730]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; synapse [GO:0045202]	ubiquitin protein ligase binding [GO:0031625]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; integrin binding [GO:0005178]; protein domain specific binding [GO:0019904]
d3zkka__d3puve1__1				Proteobacteria		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d3zkmd1_d1ggih1__1	Metazoa	Metazoa	Chordata	Chordata	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	aspartic-type endopeptidase activity [GO:0004190]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3zkmd2_d3sobl1__1	Metazoa	Metazoa	Chordata	Chordata	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	caveola [GO:0005901]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]; Wnt-Frizzled-LRP5/6 complex [GO:1990851]; apolipoprotein binding [GO:0034185]; coreceptor activity involved in canonical Wnt signaling pathway [GO:1904928]; coreceptor activity involved in Wnt signaling pathway [GO:0071936]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; kinase inhibitor activity [GO:0019210]; low-density lipoprotein particle receptor activity [GO:0005041]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; toxin transmembrane transporter activity [GO:0019534]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]; anterior/posterior pattern specification [GO:0009952]; axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; gastrulation with mouth forming second [GO:0001702]; midbrain development [GO:0030901]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; roof of mouth development [GO:0060021]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	anterior/posterior pattern specification [GO:0009952]; axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; gastrulation with mouth forming second [GO:0001702]; midbrain development [GO:0030901]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; pericardium morphogenesis [GO:0003344]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; roof of mouth development [GO:0060021]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]	caveola [GO:0005901]; cell [GO:0005623]; cell surface [GO:0009986]; cytoplasmic vesicle [GO:0031410]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; synapse [GO:0045202]; Wnt-Frizzled-LRP5/6 complex [GO:1990851]; Wnt signalosome [GO:1990909]	aspartic-type endopeptidase activity [GO:0004190]	apolipoprotein binding [GO:0034185]; coreceptor activity involved in canonical Wnt signaling pathway [GO:1904928]; coreceptor activity involved in Wnt signaling pathway [GO:0071936]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; kinase inhibitor activity [GO:0019210]; low-density lipoprotein particle receptor activity [GO:0005041]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; toxin transmembrane transporter activity [GO:0019534]; Wnt-activated receptor activity [GO:0042813]; Wnt-protein binding [GO:0017147]
d3zkmd2_d6bitk2__1	Metazoa	Metazoa	Chordata	Chordata	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]	amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-12 [GO:0071349]; cellular response to lipopolysaccharide [GO:0071222]; leukocyte migration [GO:0050900]; monocyte extravasation [GO:0035696]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB phosphorylation [GO:1903720]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macrophage inflammatory protein 1 alpha production [GO:0071641]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; neutrophil degranulation [GO:0043312]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of phagocytosis [GO:0050766]; positive regulation of T cell activation [GO:0050870]; regulation of gene expression [GO:0010468]; regulation of interferon-gamma production [GO:0032649]; regulation of interleukin-1 beta production [GO:0032651]; regulation of interleukin-6 production [GO:0032675]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of tumor necrosis factor production [GO:0032680]	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]	aspartic-type endopeptidase activity [GO:0004190]	cell-cell adhesion mediator activity [GO:0098632]; GTPase regulator activity [GO:0030695]; protein antigen binding [GO:1990405]; protein binding involved in heterotypic cell-cell adhesion [GO:0086080]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase binding [GO:1990782]; SH3 domain binding [GO:0017124]
d3zkml1_d2gj7e1__1	Metazoa	Metazoa	Chordata	Chordata	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	aspartic-type endopeptidase activity [GO:0004190]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3zknd2_d2ny4b1__1	Metazoa	Metazoa	Chordata	Chordata	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	aspartic-type endopeptidase activity [GO:0004190]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d3zkqd1_d4kzel2__1	Metazoa		Chordata		dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]		aspartic-type endopeptidase activity [GO:0004190]	
d3zkxb1_d3gmmb___1	Metazoa	Metazoa	Chordata	Chordata	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	aspartic-type endopeptidase activity [GO:0004190]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d3zl1a__d4xoba2__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]	mannose binding [GO:0005537]	mannose binding [GO:0005537]
d3zl5a__d3o6td___1	Metazoa		Platyhelminthes	Actinobacteria	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; S-nitrosoglutathione reductase activity [GO:0080007]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	disulfide oxidoreductase activity [GO:0015036]; electron transfer activity [GO:0009055]; glutathione disulfide oxidoreductase activity [GO:0015038]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; S-nitrosoglutathione reductase activity [GO:0080007]
d3zl5c__d1w4vc___1	Metazoa	Metazoa	Platyhelminthes	Chordata	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein disulfide oxidoreductase activity [GO:0015035]; protein-containing complex binding [GO:0044877]; cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cell [GO:0005623]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein-containing complex binding [GO:0044877]; protein disulfide oxidoreductase activity [GO:0015035]
d3zl5c__d3i69h1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; prostaglandin metabolic process [GO:0006693]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; steroid delta-isomerase activity [GO:0004769]
d3zl5e__d2pmtb2__1	Metazoa		Platyhelminthes	Proteobacteria	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	glutathione transferase activity [GO:0004364]
d3zl5f__d5ecob1__1	Metazoa	Viridiplantae	Platyhelminthes	Streptophyta	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cell redox homeostasis [GO:0045454]	glutathione metabolic process [GO:0006749]; regulation of growth [GO:0040008]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407]	cell [GO:0005623]	apoplast [GO:0048046]; chloroplast [GO:0009507]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]
d3zl5h__d1xpva___1	Metazoa		Platyhelminthes	Proteobacteria	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]		identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	
d3zl5h__d2ahea1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	actin cytoskeleton [GO:0015629]; apical part of cell [GO:0045177]; cell [GO:0005623]; cell surface [GO:0009986]; cell-cell junction [GO:0005911]; centrosome [GO:0005813]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; microvillus [GO:0005902]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]; angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; chloride transport [GO:0006821]; endothelial cell morphogenesis [GO:0001886]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; fertilization [GO:0009566]; keratinocyte differentiation [GO:0030216]; multicellular organism growth [GO:0035264]; negative regulation of cell migration [GO:0030336]; regulation of cytoskeleton organization [GO:0051493]; regulation of ion transmembrane transport [GO:0034765]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; vacuolar acidification [GO:0007035]	cell redox homeostasis [GO:0045454]	angiogenesis [GO:0001525]; branching morphogenesis of an epithelial tube [GO:0048754]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; chloride transport [GO:0006821]; endothelial cell morphogenesis [GO:0001886]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; fertilization [GO:0009566]; keratinocyte differentiation [GO:0030216]; multicellular organism growth [GO:0035264]; negative regulation of cell migration [GO:0030336]; regulation of cytoskeleton organization [GO:0051493]; regulation of ion transmembrane transport [GO:0034765]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; vacuolar acidification [GO:0007035]	cell [GO:0005623]	actin cytoskeleton [GO:0015629]; apical part of cell [GO:0045177]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell surface [GO:0009986]; centrosome [GO:0005813]; chloride channel complex [GO:0034707]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; microvillus [GO:0005902]; midbody [GO:0030496]; mitochondrion [GO:0005739]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	chloride channel activity [GO:0005254]; voltage-gated ion channel activity [GO:0005244]
d3zlfc1_d1jdfc2__1			Firmicutes	Proteobacteria	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]; D-glucarate catabolic process [GO:0042838]	glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	D-glucarate catabolic process [GO:0042838]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	glucarate dehydratase activity [GO:0008872]; magnesium ion binding [GO:0000287]
d3zlfd2_d2dw7p1__1			Firmicutes	Proteobacteria	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	protein homooligomerization [GO:0051260]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]		magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]
d3zlga1_d1p43a2__1		Fungi	Firmicutes	Ascomycota	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	glycolytic process [GO:0006096]; pathogenesis [GO:0009405]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of vacuole fusion, non-autophagic [GO:0032889]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; phosphopyruvate hydratase complex [GO:0000015]; plasma membrane [GO:0005886]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3zlkc__d3t7ob1__1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]; glycogenin glucosyltransferase activity [GO:0008466]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity [GO:0102751]; glycogen biosynthetic process [GO:0005978]; neutrophil degranulation [GO:0043312]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	glycogen biosynthetic process [GO:0005978]; neutrophil degranulation [GO:0043312]		cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; membrane [GO:0016020]; secretory granule lumen [GO:0034774]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	glycogenin glucosyltransferase activity [GO:0008466]; manganese ion binding [GO:0030145]; protein homodimerization activity [GO:0042803]; UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity [GO:0102751]
d3zllc__d4ho9b___1			Proteobacteria	Firmicutes	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	extracellular polysaccharide biosynthetic process [GO:0045226]			glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d3zlqd1_d1ngza1__1	Metazoa		Chordata		dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]		dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]		aspartic-type endopeptidase activity [GO:0004190]	
d3zmka2_d4zb9d2__1	Metazoa	Fungi	Arthropoda	Basidiomycota	transferase activity [GO:0016740]						transferase activity [GO:0016740]	
d3zmkc2_d2vcvm2__1	Metazoa	Metazoa	Arthropoda	Chordata	transferase activity [GO:0016740]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]
d3zmkd1_d4wf4a___1	Metazoa		Arthropoda	Proteobacteria	transferase activity [GO:0016740]	cell [GO:0005623]; periplasmic space [GO:0042597]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]; periplasmic space [GO:0042597]	transferase activity [GO:0016740]	metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]
d3zmla1_d1rqma___1	Metazoa		Arthropoda	Firmicutes	transferase activity [GO:0016740]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]	transferase activity [GO:0016740]	protein disulfide oxidoreductase activity [GO:0015035]
d3zmlb2_d4yh2b2__1	Metazoa	Metazoa	Arthropoda	Arthropoda	transferase activity [GO:0016740]	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]		glutathione metabolic process [GO:0006749]		cytoplasm [GO:0005737]	transferase activity [GO:0016740]	glutathione transferase activity [GO:0004364]
d3zmsa3_d3bhka2__1	Metazoa		Chordata	Firmicutes	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cytoplasm [GO:0005737]; sarcosine oxidase activity [GO:0008115]; tetrahydrofolate metabolic process [GO:0046653]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	tetrahydrofolate metabolic process [GO:0046653]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	sarcosine oxidase activity [GO:0008115]
d3zmta3_d1vg9e2__1	Metazoa	Metazoa	Chordata	Chordata	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; Rab-protein geranylgeranyltransferase complex [GO:0005968]; GDP-dissociation inhibitor activity [GO:0005092]; GTPase activator activity [GO:0005096]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]; protein geranylgeranylation [GO:0018344]; protein targeting to membrane [GO:0006612]; protein-containing complex assembly [GO:0065003]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	protein-containing complex assembly [GO:0065003]; protein geranylgeranylation [GO:0018344]; protein targeting to membrane [GO:0006612]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; Rab-protein geranylgeranyltransferase complex [GO:0005968]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	GDP-dissociation inhibitor activity [GO:0005092]; GTPase activator activity [GO:0005096]; protein-containing complex binding [GO:0044877]; Rab GTPase binding [GO:0017137]
d3zmva3_d1ryia2__1	Metazoa		Chordata	Firmicutes	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]; cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cellular amino acid metabolic process [GO:0006520]; response to herbicide [GO:0009635]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	FAD binding [GO:0071949]; glycine oxidase activity [GO:0043799]; oxidoreductase activity [GO:0016491]
d3zmza3_d1h84a2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]; flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]; polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	apoplast [GO:0048046]; plant-type cell wall [GO:0009505]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	flavin adenine dinucleotide binding [GO:0050660]; N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052898]; N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052893]; N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity [GO:0052897]; oxidoreductase activity [GO:0016491]; polyamine oxidase activity [GO:0046592]; spermidine oxidase (propane-1,3-diamine-forming) activity [GO:0052896]; spermine oxidase (propane-1,3-diamine-forming) activity [GO:0052900]
d3zn0a3_d2igod2__1	Metazoa	Fungi	Chordata	Basidiomycota	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]		DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]		DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]
d3zn1a3_d1ojdh2__1	Metazoa	Metazoa	Chordata	Chordata	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]
d3zn1a3_d1ykjb2__1	Metazoa		Chordata	Proteobacteria	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; transcriptional repressor complex [GO:0017053]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; benzoate catabolic process via hydroxylation [GO:0043640]	blood coagulation [GO:0007596]; histone H4 deacetylation [GO:0070933]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	benzoate catabolic process via hydroxylation [GO:0043640]	DNA repair complex [GO:1990391]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; transcription factor complex [GO:0005667]		DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	4-hydroxybenzoate 3-monooxygenase activity [GO:0018659]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]
d3zn2a__d3byzc___1		Metazoa	Proteobacteria	Chordata		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]		11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d3zn2a__d4bl5i1__1		Metazoa	Proteobacteria	Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]		'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]
d3zngf__d2zpya3__1	Metazoa	Metazoa	Chordata	Chordata	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing involved in inflammatory response [GO:0002246]; wound healing, spreading of cells [GO:0044319]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cytokine-mediated signaling pathway [GO:0019221]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; macrophage fusion [GO:0034238]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of regulatory T cell differentiation [GO:0045590]; neuron projection development [GO:0031175]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell growth [GO:0001558]; regulation of lamellipodium morphogenesis [GO:2000392]; T cell activation [GO:0042110]; Wnt signaling pathway [GO:0016055]; wound healing, spreading of cells [GO:0044319]; wound healing involved in inflammatory response [GO:0002246]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ubiquitin protein ligase binding [GO:0031625]	epidermal growth factor receptor binding [GO:0005154]; hyaluronic acid binding [GO:0005540]; phosphoprotein binding [GO:0051219]; protein kinase binding [GO:0019901]; transmembrane signaling receptor activity [GO:0004888]; type II transforming growth factor beta receptor binding [GO:0005114]
d3znjd__d2asya1__1			Actinobacteria	Proteobacteria	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	cytosol [GO:0005829]; oxidoreductase activity [GO:0016491]	beta-ketoadipate pathway [GO:0042952]			cytosol [GO:0005829]	muconolactone delta-isomerase activity [GO:0016159]	oxidoreductase activity [GO:0016491]
d3znjf__d4w7ka___1		Fungi	Actinobacteria	Basidiomycota	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	beta-ketoadipate pathway [GO:0042952]			extracellular region [GO:0005576]	muconolactone delta-isomerase activity [GO:0016159]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3znji__d2hiqb___1			Actinobacteria	Proteobacteria	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	cytosol [GO:0005829]; oxidoreductase activity [GO:0016491]	beta-ketoadipate pathway [GO:0042952]			cytosol [GO:0005829]	muconolactone delta-isomerase activity [GO:0016159]	oxidoreductase activity [GO:0016491]
d3znjj__d5y02l___1		Viridiplantae	Actinobacteria	Streptophyta	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	lyase activity [GO:0016829]	beta-ketoadipate pathway [GO:0042952]				muconolactone delta-isomerase activity [GO:0016159]	lyase activity [GO:0016829]
d3znjk__d1tr0g___1		Viridiplantae	Actinobacteria	Streptophyta	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]		beta-ketoadipate pathway [GO:0042952]				muconolactone delta-isomerase activity [GO:0016159]	
d3znjk__d2bbea___1			Actinobacteria	Proteobacteria	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	cytosol [GO:0005829]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]	beta-ketoadipate pathway [GO:0042952]			cytosol [GO:0005829]	muconolactone delta-isomerase activity [GO:0016159]	monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]
d3znjl__d1tr0u___1		Viridiplantae	Actinobacteria	Streptophyta	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]		beta-ketoadipate pathway [GO:0042952]				muconolactone delta-isomerase activity [GO:0016159]	
d3znjl__d5y02f___1		Viridiplantae	Actinobacteria	Streptophyta	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	lyase activity [GO:0016829]	beta-ketoadipate pathway [GO:0042952]				muconolactone delta-isomerase activity [GO:0016159]	lyase activity [GO:0016829]
d3znjm__d2d3qa1__1		Fungi	Actinobacteria	Basidiomycota	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	beta-ketoadipate pathway [GO:0042952]				muconolactone delta-isomerase activity [GO:0016159]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3znjs__d1tr0a___1		Viridiplantae	Actinobacteria	Streptophyta	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]		beta-ketoadipate pathway [GO:0042952]				muconolactone delta-isomerase activity [GO:0016159]	
d3znjv__d2zdob1__1			Actinobacteria	Firmicutes	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	cell [GO:0005623]; cytoplasm [GO:0005737]; heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; heme catabolic process [GO:0042167]; iron import into cell [GO:0033212]	beta-ketoadipate pathway [GO:0042952]	heme catabolic process [GO:0042167]; iron import into cell [GO:0033212]		cell [GO:0005623]; cytoplasm [GO:0005737]	muconolactone delta-isomerase activity [GO:0016159]	heme binding [GO:0020037]; heme oxygenase (decyclizing) activity [GO:0004392]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]
d3znkc__d5bnye___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3znla__d1jsda___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3znle__d4f23c1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3znma__d1jsia___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3znma__d1uf2r2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]; RNA binding [GO:0003723]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell cytoplasm [GO:0030430]; viral capsid [GO:0019028]	host cell surface receptor binding [GO:0046789]	RNA binding [GO:0003723]
d3znmc__d4unya___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3znub__d1tr0y___1		Viridiplantae	Actinobacteria	Streptophyta	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]		beta-ketoadipate pathway [GO:0042952]				muconolactone delta-isomerase activity [GO:0016159]	
d3znuh__d1y0hb___1			Actinobacteria	Actinobacteria	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	monooxygenase activity [GO:0004497]	beta-ketoadipate pathway [GO:0042952]				muconolactone delta-isomerase activity [GO:0016159]	monooxygenase activity [GO:0004497]
d3znzb1_d3b1lx___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	aggresome [GO:0016235]; axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular vesicle [GO:0097708]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; mitochondrion-derived vesicle [GO:0099073]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; ubiquitin ligase complex [GO:0000151]; actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; chaperone binding [GO:0051087]; cullin family protein binding [GO:0097602]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; F-box domain binding [GO:1990444]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; Hsp70 protein binding [GO:0030544]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; phospholipase binding [GO:0043274]; protein kinase binding [GO:0019901]; protein-containing complex binding [GO:0044877]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; tubulin binding [GO:0015631]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-specific protease binding [GO:1990381]; adult locomotory behavior [GO:0008344]; aggresome assembly [GO:0070842]; autophagy of mitochondrion [GO:0000422]; cellular protein catabolic process [GO:0044257]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to L-glutamate [GO:1905232]; cellular response to toxic substance [GO:0097237]; dopamine metabolic process [GO:0042417]; dopamine uptake involved in synaptic transmission [GO:0051583]; free ubiquitin chain polymerization [GO:0010994]; learning [GO:0007612]; locomotory behavior [GO:0007626]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; mitochondrion to lysosome transport [GO:0099074]; mitophagy [GO:0000423]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell death [GO:0060548]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903382]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of exosomal secretion [GO:1903542]; negative regulation of gene expression [GO:0010629]; negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676]; negative regulation of intralumenal vesicle formation [GO:1905366]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of JNK cascade [GO:0046329]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of primary amine oxidase activity [GO:1902283]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of spontaneous neurotransmitter secretion [GO:1904049]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron cellular homeostasis [GO:0070050]; norepinephrine metabolic process [GO:0042415]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of dendrite extension [GO:1903861]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of mitophagy [GO:1901526]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of neurotransmitter uptake [GO:0051582]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein localization to membrane [GO:1905477]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K6-linked ubiquitination [GO:0085020]; protein K63-linked ubiquitination [GO:0070534]; protein localization to mitochondrion [GO:0070585]; protein metabolic process [GO:0019538]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of dopamine metabolic process [GO:0042053]; regulation of gene expression [GO:0010468]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein stability [GO:0031647]; regulation of protein ubiquitination [GO:0031396]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; startle response [GO:0001964]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; ubiquitin-dependent protein catabolic process [GO:0006511]; zinc ion homeostasis [GO:0055069]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	adult locomotory behavior [GO:0008344]; aggresome assembly [GO:0070842]; autophagy of mitochondrion [GO:0000422]; cellular protein catabolic process [GO:0044257]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to L-glutamate [GO:1905232]; cellular response to toxic substance [GO:0097237]; dopamine metabolic process [GO:0042417]; dopamine uptake involved in synaptic transmission [GO:0051583]; free ubiquitin chain polymerization [GO:0010994]; learning [GO:0007612]; locomotory behavior [GO:0007626]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; mitochondrion to lysosome transport [GO:0099074]; mitophagy [GO:0000423]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell death [GO:0060548]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903382]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of exosomal secretion [GO:1903542]; negative regulation of gene expression [GO:0010629]; negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676]; negative regulation of intralumenal vesicle formation [GO:1905366]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of JNK cascade [GO:0046329]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of primary amine oxidase activity [GO:1902283]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of spontaneous neurotransmitter secretion [GO:1904049]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron cellular homeostasis [GO:0070050]; norepinephrine metabolic process [GO:0042415]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of dendrite extension [GO:1903861]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of mitophagy [GO:1901526]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of neurotransmitter uptake [GO:0051582]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein localization to membrane [GO:1905477]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein localization to mitochondrion [GO:0070585]; protein metabolic process [GO:0019538]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of dopamine metabolic process [GO:0042053]; regulation of gene expression [GO:0010468]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein stability [GO:0031647]; regulation of protein ubiquitination [GO:0031396]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; startle response [GO:0001964]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; ubiquitin-dependent protein catabolic process [GO:0006511]; zinc ion homeostasis [GO:0055069]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	aggresome [GO:0016235]; axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; intracellular vesicle [GO:0097708]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; mitochondrion-derived vesicle [GO:0099073]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; Parkin-FBXW7-Cul1 ubiquitin ligase complex [GO:1990452]; perinuclear region of cytoplasm [GO:0048471]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynapse [GO:0098793]; protein-containing complex [GO:0032991]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; ubiquitin ligase complex [GO:0000151]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	actin binding [GO:0003779]; beta-catenin binding [GO:0008013]; chaperone binding [GO:0051087]; cullin family protein binding [GO:0097602]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; enzyme binding [GO:0019899]; F-box domain binding [GO:1990444]; G protein-coupled receptor binding [GO:0001664]; heat shock protein binding [GO:0031072]; histone deacetylase binding [GO:0042826]; Hsp70 protein binding [GO:0030544]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; metal ion binding [GO:0046872]; PDZ domain binding [GO:0030165]; phospholipase binding [GO:0043274]; protein-containing complex binding [GO:0044877]; protein kinase binding [GO:0019901]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; tubulin binding [GO:0015631]; ubiquitin binding [GO:0043130]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; ubiquitin-specific protease binding [GO:1990381]
d3zo0a1_d3oj2c1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]; activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	activation of MAPK activity [GO:0000187]; activation of protein kinase B activity [GO:0032148]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; branch elongation involved in ureteric bud branching [GO:0060681]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; fibroblast growth factor receptor signaling pathway [GO:0008543]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; mesonephric epithelium development [GO:0072163]; multicellular organism development [GO:0007275]; organ induction [GO:0001759]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell division [GO:0051781]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000544]; regulation of endothelial tube morphogenesis [GO:1901509]; signal transduction [GO:0007165]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	fibroblast growth factor receptor binding [GO:0005104]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; Hsp70 protein binding [GO:0030544]; integrin binding [GO:0005178]; S100 protein binding [GO:0044548]
d3zo0a2_d3c6sa2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3zo0b1_d3m3ec1__1	Metazoa	Fungi	Chordata	Basidiomycota	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; response to bacterium [GO:0009617]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d3zo7a__d5loqa___1			Actinobacteria	Firmicutes	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	beta-ketoadipate pathway [GO:0042952]				muconolactone delta-isomerase activity [GO:0016159]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3zo7c__d3vega___1			Actinobacteria	Actinobacteria	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	beta-ketoadipate pathway [GO:0042952]				muconolactone delta-isomerase activity [GO:0016159]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d3zo7d__d5y02c1__1		Viridiplantae	Actinobacteria	Streptophyta	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	lyase activity [GO:0016829]	beta-ketoadipate pathway [GO:0042952]				muconolactone delta-isomerase activity [GO:0016159]	lyase activity [GO:0016829]
d3zo7i__d3znuh___1			Actinobacteria	Actinobacteria	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	beta-ketoadipate pathway [GO:0042952]	beta-ketoadipate pathway [GO:0042952]			muconolactone delta-isomerase activity [GO:0016159]	muconolactone delta-isomerase activity [GO:0016159]
d3zo7j__d1tr0h___1		Viridiplantae	Actinobacteria	Streptophyta	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]		beta-ketoadipate pathway [GO:0042952]				muconolactone delta-isomerase activity [GO:0016159]	
d3zo7j__d4fpif___1			Actinobacteria	Actinobacteria	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	muconolactone delta-isomerase activity [GO:0016159]; beta-ketoadipate pathway [GO:0042952]	beta-ketoadipate pathway [GO:0042952]	beta-ketoadipate pathway [GO:0042952]			muconolactone delta-isomerase activity [GO:0016159]	muconolactone delta-isomerase activity [GO:0016159]
d3zo8c__d3lmec1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		cytoplasm [GO:0005737]		chorismate mutase activity [GO:0004106]	
d3zo8f__d3r0pe___1			Firmicutes		cytoplasm [GO:0005737]; chorismate mutase activity [GO:0004106]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate metabolic process [GO:0046417]		cytoplasm [GO:0005737]		chorismate mutase activity [GO:0004106]	
d3zofb__d3tgvd1__1			Deinococcus-Thermus	Proteobacteria	FMN binding [GO:0010181]	coenzyme F420 binding [GO:0070967]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; heme transport [GO:0015886]		heme transport [GO:0015886]			FMN binding [GO:0010181]	coenzyme F420 binding [GO:0070967]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]
d3zoha__d3a6ra___1			Deinococcus-Thermus	Proteobacteria	FMN binding [GO:0010181]	cytoplasm [GO:0005737]; cofactor binding [GO:0048037]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cytoplasm [GO:0005737]	FMN binding [GO:0010181]	cofactor binding [GO:0048037]
d3zohc__d5jaba___1			Deinococcus-Thermus	Actinobacteria	FMN binding [GO:0010181]	cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]; coenzyme F420 binding [GO:0070967]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; protein homodimerization activity [GO:0042803]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cell surface [GO:0009986]; cell wall [GO:0005618]; extracellular region [GO:0005576]	FMN binding [GO:0010181]	coenzyme F420 binding [GO:0070967]; oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627]; protein homodimerization activity [GO:0042803]
d3zoia__d4bhga2__1	Fungi	Metazoa	Ascomycota	Chordata	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]; penicillin biosynthetic process [GO:0042318]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]; carnitine biosynthetic process [GO:0045329]	penicillin biosynthetic process [GO:0042318]	carnitine biosynthetic process [GO:0045329]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; isopenicillin-N synthase activity [GO:0016216]; L-ascorbic acid binding [GO:0031418]	gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]
d3zood__d1dw2c___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; apoptotic process [GO:0006915]; cellular respiration [GO:0045333]; cellular response to oxidative stress [GO:0034599]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrion organization [GO:0007005]; protein dephosphorylation [GO:0006470]		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; protein phosphatase type 2A complex [GO:0000159]; respirasome [GO:0070469]		electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity [GO:0045155]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3zoqa__d2zhxa___1				Actinobacteria	interaction with host [GO:0051701]; viral process [GO:0016032]	mitochondrion [GO:0005739]; nucleus [GO:0005634]; uracil DNA N-glycosylase activity [GO:0004844]; base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]	interaction with host [GO:0051701]; viral process [GO:0016032]	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]		mitochondrion [GO:0005739]; nucleus [GO:0005634]		uracil DNA N-glycosylase activity [GO:0004844]
d3zowf__d1hcma1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d3zowg__d2d0wb___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methanol metabolic process [GO:0015945]		methanol metabolic process [GO:0015945]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3zowh__d1pbya1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3zowi__d1kx7a1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3zowm__d1n90b1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; hydroxylamine reductase activity [GO:0050418]; metal ion binding [GO:0046872]; nitrite reductase (NO-forming) activity [GO:0050421]
d3zowo__d3cx5o1__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]		mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	periplasmic space [GO:0042597]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; respirasome [GO:0070469]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3zowp__d1foca___1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]			periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d3zowp__d2c1vb1__1			Proteobacteria		periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]				periplasmic space [GO:0042597]		electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	
d3zoya__d3l71q1__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; 2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]			periplasmic space [GO:0042597]	integral component of membrane [GO:0016021]; mitochondrial respiratory chain complex III [GO:0005750]; mitochondrial respiratory chain complex IV [GO:0005751]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; ubiquinol-cytochrome-c reductase activity [GO:0008121]
d3zp1e__d4cywc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3zp2e__d4cyve___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3zp2e__d4edac___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3zp3e__d4xq5e___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3zpbe__d4bh0c___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d3zpcb2_d1cz3a___1			Proteobacteria	Thermotogae	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	cytosol [GO:0005829]; dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	riboflavin biosynthetic process [GO:0009231]	dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		cytosol [GO:0005829]	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]	dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]
d3zpga1_d1wn5c___1		Fungi	Proteobacteria	Ascomycota	5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]; riboflavin biosynthetic process [GO:0009231]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]; response to antibiotic [GO:0046677]	riboflavin biosynthetic process [GO:0009231]	response to antibiotic [GO:0046677]			5-amino-6-(5-phosphoribosylamino)uracil reductase activity [GO:0008703]; diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [GO:0008835]; NADP binding [GO:0050661]; zinc ion binding [GO:0008270]	blasticidin-S deaminase activity [GO:0047711]; zinc ion binding [GO:0008270]
d3zpsa__d2g94a___1		Metazoa		Chordata	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d3zpsb__d3dk1a___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3zpta__d2whha2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d3zptb__d5p59a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3zpub__d3vlaa___1		Viridiplantae		Streptophyta	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d3zq3b__d4oryh___1	Metazoa	Metazoa	Chordata	Chordata	small molecule binding [GO:0036094]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]		cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]		endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	small molecule binding [GO:0036094]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d3zq3c__d1eala___1	Metazoa	Metazoa	Chordata	Chordata	small molecule binding [GO:0036094]	cytoplasm [GO:0005737]; membrane [GO:0016020]; lipid binding [GO:0008289]; lipid transport [GO:0006869]		lipid transport [GO:0006869]		cytoplasm [GO:0005737]; membrane [GO:0016020]	small molecule binding [GO:0036094]	lipid binding [GO:0008289]
d3zq5a1_d3c2wc3__1			Cyanobacteria	Proteobacteria	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; red or far-red light photoreceptor activity [GO:0009883]; detection of visible light [GO:0009584]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; red, far-red light phototransduction [GO:0009585]; regulation of transcription, DNA-templated [GO:0006355]; response to red or far red light [GO:0009639]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; red, far-red light phototransduction [GO:0009585]; regulation of transcription, DNA-templated [GO:0006355]; response to red or far red light [GO:0009639]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; red or far-red light photoreceptor activity [GO:0009883]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d3zq5a1_d3ue6e___1			Cyanobacteria		ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; red or far-red light photoreceptor activity [GO:0009883]; detection of visible light [GO:0009584]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; red, far-red light phototransduction [GO:0009585]; regulation of transcription, DNA-templated [GO:0006355]; response to red or far red light [GO:0009639]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]	detection of visible light [GO:0009584]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; red, far-red light phototransduction [GO:0009585]; regulation of transcription, DNA-templated [GO:0006355]; response to red or far red light [GO:0009639]				ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; red or far-red light photoreceptor activity [GO:0009883]	DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d3zq5a3_d4glqa___1			Cyanobacteria	Cyanobacteria	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; red or far-red light photoreceptor activity [GO:0009883]; detection of visible light [GO:0009584]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; red, far-red light phototransduction [GO:0009585]; regulation of transcription, DNA-templated [GO:0006355]; response to red or far red light [GO:0009639]	integral component of membrane [GO:0016021]; protein-chromophore linkage [GO:0018298]; signal transduction [GO:0007165]	detection of visible light [GO:0009584]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; red, far-red light phototransduction [GO:0009585]; regulation of transcription, DNA-templated [GO:0006355]; response to red or far red light [GO:0009639]	protein-chromophore linkage [GO:0018298]; signal transduction [GO:0007165]		integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay sensor kinase activity [GO:0000155]; protein histidine kinase activity [GO:0004673]; red or far-red light photoreceptor activity [GO:0009883]	
d3zqaa__d4i2rb___1			Proteobacteria	Proteobacteria	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]	glycine betaine biosynthetic process from choline [GO:0019285]				aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620]
d3zqac__d3ifgp1__1			Proteobacteria		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]		glycine betaine biosynthetic process from choline [GO:0019285]				aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	
d3zqad__d1cw3b___1		Metazoa	Proteobacteria	Chordata	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]; alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]	glycine betaine biosynthetic process from choline [GO:0019285]	alcohol metabolic process [GO:0006066]; carbohydrate metabolic process [GO:0005975]; ethanol catabolic process [GO:0006068]; ethanol oxidation [GO:0006069]		extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; electron transfer activity [GO:0009055]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; NAD binding [GO:0051287]
d3zqad__d5gtla___1			Proteobacteria	Firmicutes	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]	glycine betaine biosynthetic process from choline [GO:0019285]				aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]
d3zqua__d1g5ql___1			Proteobacteria	Firmicutes	carboxy-lyase activity [GO:0016831]; flavin prenyltransferase activity [GO:0106141]; prenyltransferase activity [GO:0004659]; coenzyme biosynthetic process [GO:0009108]	lyase activity [GO:0016829]	coenzyme biosynthetic process [GO:0009108]				carboxy-lyase activity [GO:0016831]; flavin prenyltransferase activity [GO:0106141]; prenyltransferase activity [GO:0004659]	lyase activity [GO:0016829]
d3zqxa1_d5gxya2__1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d3zqya__d5jvea___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3zr4b__d4ofwe1__1		Viridiplantae	Thermotogae	Streptophyta	cytoplasm [GO:0005737]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; histidine biosynthetic process [GO:0000105]	cytosol [GO:0005829]; glyoxalase III activity [GO:0019172]; lactoylglutathione lyase activity [GO:0004462]	histidine biosynthetic process [GO:0000105]		cytoplasm [GO:0005737]	cytosol [GO:0005829]	imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]	glyoxalase III activity [GO:0019172]; lactoylglutathione lyase activity [GO:0004462]
d3zr4d__d4ofwb2__1		Viridiplantae	Thermotogae	Streptophyta	cytoplasm [GO:0005737]; imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]; histidine biosynthetic process [GO:0000105]	cytosol [GO:0005829]; glyoxalase III activity [GO:0019172]; lactoylglutathione lyase activity [GO:0004462]	histidine biosynthetic process [GO:0000105]		cytoplasm [GO:0005737]	cytosol [GO:0005829]	imidazoleglycerol-phosphate synthase activity [GO:0000107]; lyase activity [GO:0016829]	glyoxalase III activity [GO:0019172]; lactoylglutathione lyase activity [GO:0004462]
d3zrcj__d3dvnu2__1	Metazoa	Metazoa	Chordata	Chordata	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	ubiquitin protein ligase binding [GO:0031625]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d3zrda1_d3gixa___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; cell cycle [GO:0007049]; mRNA splicing, via spliceosome [GO:0000398]	cell redox homeostasis [GO:0045454]	cell cycle [GO:0007049]; mRNA splicing, via spliceosome [GO:0000398]	cell [GO:0005623]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	thioredoxin peroxidase activity [GO:0008379]	
d3zrea1_d1uuli___1			Proteobacteria		cell [GO:0005623]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]		thioredoxin peroxidase activity [GO:0008379]	
d3zsea__d1xnca___1			Actinobacteria	Firmicutes	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; xylan catabolic process [GO:0045493]	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]	endo-1,4-beta-xylanase activity [GO:0031176]
d3zsea__d2r0fa___1		Fungi	Actinobacteria	Basidiomycota	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]; xylan catabolic process [GO:0045493]	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]	xylan catabolic process [GO:0045493]			cell wall [GO:0005618]; extracellular region [GO:0005576]	endo-1,4-beta-xylanase activity [GO:0031176]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]
d3zsfa__d2al4f___1		Metazoa	Proteobacteria	Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d3zsja__d1q8pb___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]		carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3zsla1_d2ctva___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]		carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d3zsnc__d1o76a___1			Actinobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3ztcg__d2o6vc___1	Metazoa	Metazoa	Chordata	Chordata	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d3ztea__d1gtfj___1			Firmicutes	Firmicutes	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d3ztec__d1c9so___1			Firmicutes	Firmicutes	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d3zteg__d1utdk___1			Firmicutes	Firmicutes	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d3zten__d1wapu___1			Firmicutes	Firmicutes	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3zteq__d1wapg___1			Firmicutes	Firmicutes	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			RNA binding [GO:0003723]	RNA binding [GO:0003723]
d3ztla__d1ovnb2__1	Metazoa	Metazoa	Platyhelminthes	Arthropoda	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; protein homodimerization activity [GO:0042803]; dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	cell redox homeostasis [GO:0045454]	dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	cell [GO:0005623]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	protein homodimerization activity [GO:0042803]
d3ztla__d1w89a1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein disulfide oxidoreductase activity [GO:0015035]; protein-containing complex binding [GO:0044877]; cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; glycerol ether metabolic process [GO:0006662]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfur amino acid catabolic process [GO:0000098]	cell [GO:0005623]	cell [GO:0005623]; dendrite [GO:0030425]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	peptide-methionine (R)-S-oxide reductase activity [GO:0033743]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; protein-containing complex binding [GO:0044877]; protein disulfide oxidoreductase activity [GO:0015035]
d3ztlc__d2vm2a___1	Metazoa	Viridiplantae	Platyhelminthes	Streptophyta	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]	cell [GO:0005623]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	protein disulfide oxidoreductase activity [GO:0015035]
d3ztle__d2gqka1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]; copper ion binding [GO:0005507]; cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cell redox homeostasis [GO:0045454]	cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	cell [GO:0005623]	cell [GO:0005623]; host cell mitochondrial intermembrane space [GO:0072492]; integral component of mitochondrial inner membrane [GO:0031305]; mitochondrion [GO:0005739]; myofibril [GO:0030016]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	copper ion binding [GO:0005507]
d3ztlf__d1f6md___1	Metazoa		Platyhelminthes	Proteobacteria	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d3ztlf__d3zmla1__1	Metazoa	Metazoa	Platyhelminthes	Arthropoda	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	transferase activity [GO:0016740]	cell redox homeostasis [GO:0045454]		cell [GO:0005623]		identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	transferase activity [GO:0016740]
d3ztlh__d4yqmb1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d3ztli__d4jrra1__1	Metazoa		Platyhelminthes	Proteobacteria	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; periplasmic space [GO:0042597]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]; periplasmic space [GO:0042597]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	protein disulfide oxidoreductase activity [GO:0015035]
d3ztma__d3nmkd___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3ztnl1_d3nz8b2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d3ztqb__d4uofb___1		Metazoa	Aquificae	Arthropoda	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztqe__d6ay1h___1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztrb__d3evoa1__1			Aquificae		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztrc__d1vyak___1		Viridiplantae	Aquificae	Streptophyta	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztrd__d2zuaa___1			Aquificae	Euryarchaeota	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztrg__d3gpac1__1			Aquificae		cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztsb__d3q8ye___1			Aquificae	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztsc__d3q8uf___1			Aquificae	Firmicutes	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztsc__d6ay1b___1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztsd__d1s57c___1		Viridiplantae	Aquificae	Streptophyta	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	auxin-activated signaling pathway [GO:0009734]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; red, far-red light phototransduction [GO:0009585]; response to hydrogen peroxide [GO:0042542]; response to UV [GO:0009411]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plastid [GO:0009536]; thylakoid [GO:0009579]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztsf__d1vyac___1		Viridiplantae	Aquificae	Streptophyta	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	nucleus [GO:0005634]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein hexamerization [GO:0034214]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	nucleus [GO:0005634]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztsh__d1bhne___1		Metazoa	Aquificae	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; nervous system development [GO:0007399]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cell differentiation [GO:0030154]; CTP biosynthetic process [GO:0006241]; endocytosis [GO:0006897]; GTP biosynthetic process [GO:0006183]; nervous system development [GO:0007399]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztsi__d4uoga___1		Metazoa	Aquificae	Arthropoda	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztsj__d2hurd___1			Aquificae	Proteobacteria	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d3ztsk__d5u2if1__1			Aquificae	Heterolobosea	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d3zttd__d4utob___1			Firmicutes	Firmicutes	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	cell adhesion [GO:0007155]; metal ion transport [GO:0030001]	plasma membrane [GO:0005886]	plasma membrane [GO:0005886]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d3zttd__d5y8aa1__1			Firmicutes	Proteobacteria	plasma membrane [GO:0005886]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]; metal ion transport [GO:0030001]		cell adhesion [GO:0007155]; metal ion transport [GO:0030001]		plasma membrane [GO:0005886]		metal ion binding [GO:0046872]	
d3zumh2_d5prch1__1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]; photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	plasma membrane light-harvesting complex [GO:0030077]; plasma membrane-derived chromatophore membrane [GO:0042717]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	photosynthetic electron transport in photosystem II [GO:0009772]; protein-chromophore linkage [GO:0018298]	photosynthesis [GO:0015979]; photosynthesis, light reaction [GO:0019684]	integral component of membrane [GO:0016021]; plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	plasma membrane-derived chromatophore membrane [GO:0042717]; plasma membrane light-harvesting complex [GO:0030077]	bacteriochlorophyll binding [GO:0042314]; electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity [GO:0045156]; metal ion binding [GO:0046872]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d3zuna__d3m63b___1	Metazoa	Fungi	Chordata	Ascomycota	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151]; ubiquitin-ubiquitin ligase activity [GO:0034450]; positive regulation of protein ubiquitination [GO:0031398]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	positive regulation of protein ubiquitination [GO:0031398]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin ligase complex [GO:0000151]	ubiquitin protein ligase binding [GO:0031625]	ubiquitin-ubiquitin ligase activity [GO:0034450]
d3zvca1_d4a6lb___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3zvia1_d2dw6a2__1			Firmicutes	Proteobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]; glutamate catabolic process via L-citramalate [GO:0019553]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]; protein homooligomerization [GO:0051260]	glutamate catabolic process via L-citramalate [GO:0019553]	protein homooligomerization [GO:0051260]			cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]	D(-)-tartrate dehydratase activity [GO:0047808]; magnesium ion binding [GO:0000287]
d3zvia2_d2akmb1__1		Metazoa	Firmicutes	Chordata	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]; glutamate catabolic process via L-citramalate [GO:0019553]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	glutamate catabolic process via L-citramalate [GO:0019553]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; membrane [GO:0016020]; perikaryon [GO:0043204]; phosphopyruvate hydratase complex [GO:0000015]; photoreceptor inner segment [GO:0001917]; plasma membrane [GO:0005886]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3zvib2_d1e9ia1__1			Firmicutes	Proteobacteria	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]; glutamate catabolic process via L-citramalate [GO:0019553]	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	glutamate catabolic process via L-citramalate [GO:0019553]	glycolytic process [GO:0006096]		cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]	cobalamin binding [GO:0031419]; metal ion binding [GO:0046872]; methylaspartate ammonia-lyase activity [GO:0050096]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d3zvjb1_d1yf1i___1	Metazoa		Platyhelminthes	Proteobacteria	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	thioredoxin peroxidase activity [GO:0008379]
d3zvjf1_d2c0ga2__1	Metazoa	Metazoa	Platyhelminthes	Arthropoda	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; protein homodimerization activity [GO:0042803]; dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	cell redox homeostasis [GO:0045454]	dorsal/ventral axis specification [GO:0009950]; embryo development ending in birth or egg hatching [GO:0009792]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; regulation of multicellular organism growth [GO:0040014]	cell [GO:0005623]	endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	protein homodimerization activity [GO:0042803]
d3zvjf1_d4l0uc1__1	Metazoa		Platyhelminthes	Apicomplexa	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	peroxiredoxin activity [GO:0051920]
d3zvjg__d4k9za___1	Metazoa		Platyhelminthes	Bacteroidetes	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; oxidoreductase activity [GO:0016491]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	oxidoreductase activity [GO:0016491]
d3zvjh__d4i5qa2__1	Metazoa		Platyhelminthes	Proteobacteria	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; periplasmic space [GO:0042597]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]; periplasmic space [GO:0042597]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	
d3zvjk1_d2vcvp1__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell redox homeostasis [GO:0045454]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cell [GO:0005623]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	glutathione transferase activity [GO:0004364]
d3zvjm1_d1c72b2__1	Metazoa	Metazoa	Platyhelminthes	Chordata	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]	glutathione metabolic process [GO:0006749]; nitrobenzene metabolic process [GO:0018916]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]	cytosol [GO:0005829]; intercellular bridge [GO:0045171]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]
d3zvjn__d4l0uj___1	Metazoa		Platyhelminthes	Apicomplexa	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell [GO:0005623]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell redox homeostasis [GO:0045454]	cell [GO:0005623]	cell [GO:0005623]	identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	peroxiredoxin activity [GO:0051920]
d3zvjp1_d2obkd___1	Metazoa		Platyhelminthes	Proteobacteria	cell [GO:0005623]; identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]; cell redox homeostasis [GO:0045454]		cell redox homeostasis [GO:0045454]		cell [GO:0005623]		identical protein binding [GO:0042802]; peroxidase activity [GO:0004601]; peroxiredoxin activity [GO:0051920]	
d3zvxa__d1v6ib___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]					carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d3zvxb__d2d7ff___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]		negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell division [GO:0051781]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of defense response to virus [GO:0050688]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]; monosaccharide binding [GO:0048029]
d3zvxb__d5jmcg1__1	Viridiplantae		Streptophyta	Firmicutes	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]		negative regulation of neurotransmitter secretion [GO:0046929]		cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d3zwhb__d4pala___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell leading edge [GO:0031252]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin-dependent ATPase activity [GO:0030898]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]; actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]; calcium ion binding [GO:0005509]	actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]		actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell leading edge [GO:0031252]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]	axon [GO:0030424]; axon terminus [GO:0043679]; cell [GO:0005623]; dendrite [GO:0030425]	actin binding [GO:0003779]; actin-dependent ATPase activity [GO:0030898]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]	calcium ion binding [GO:0005509]
d3zwma__d1s3fc___1	Metazoa		Mollusca	Firmicutes	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	nucleoside deoxyribosyltransferase activity [GO:0050144]	single fertilization [GO:0007338]		cytoplasmic vesicle [GO:0031410]		NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	nucleoside deoxyribosyltransferase activity [GO:0050144]
d3zwmh1_d2o3qa___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d3zwob__d3dzha___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d3zwqa__d4dnqi___1		Viridiplantae	Crenarchaeota	Streptophyta	hydrolase activity [GO:0016787]	hydrolase activity, acting on ester bonds [GO:0016788]; secondary shoot formation [GO:0010223]; strigolactone biosynthetic process [GO:1901601]		secondary shoot formation [GO:0010223]; strigolactone biosynthetic process [GO:1901601]			hydrolase activity [GO:0016787]	hydrolase activity, acting on ester bonds [GO:0016788]
d3zwva__d2i66a___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d3zwvb__d2o3ta___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d3zwvh__d3dzjb___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d3zwwg__d3i9la___1	Metazoa	Metazoa	Mollusca	Mollusca	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	single fertilization [GO:0007338]	single fertilization [GO:0007338]	cytoplasmic vesicle [GO:0031410]	cytoplasmic vesicle [GO:0031410]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]
d3zwxa__d1s2ib___1	Metazoa		Mollusca	Firmicutes	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	nucleoside deoxyribosyltransferase activity [GO:0050144]	single fertilization [GO:0007338]		cytoplasmic vesicle [GO:0031410]		NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	nucleoside deoxyribosyltransferase activity [GO:0050144]
d3zwxe__d3i9na___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]	basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d3zwxg__d1t1jb1__1	Metazoa		Mollusca	Proteobacteria	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]		single fertilization [GO:0007338]		cytoplasmic vesicle [GO:0031410]		NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	
d3zwya__d1isha___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]; ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d3zwyd1_d1f8xb___1	Metazoa		Mollusca	Firmicutes	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	nucleoside deoxyribosyltransferase activity [GO:0050144]; nucleotide salvage [GO:0043173]	single fertilization [GO:0007338]	nucleotide salvage [GO:0043173]	cytoplasmic vesicle [GO:0031410]		NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	nucleoside deoxyribosyltransferase activity [GO:0050144]
d3zwye__d1isja___1	Metazoa	Metazoa	Mollusca	Chordata	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]; ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	single fertilization [GO:0007338]	humoral immune response [GO:0006959]; NAD metabolic process [GO:0019674]; neutrophil degranulation [GO:0043312]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell population proliferation [GO:0008284]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cellular extravasation [GO:0002691]; regulation of inflammatory response [GO:0050727]; regulation of integrin-mediated signaling pathway [GO:2001044]; regulation of neutrophil chemotaxis [GO:0090022]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of superoxide metabolic process [GO:0090322]; signal transduction [GO:0007165]	cytoplasmic vesicle [GO:0031410]	anchored component of membrane [GO:0031225]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extrinsic component of membrane [GO:0019898]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; uropod [GO:0001931]	NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	ADP-ribosyl cyclase activity [GO:0061811]; cyclic ADP-ribose hydrolase [GO:0061812]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]
d3zwyg__d1s2ic___1	Metazoa		Mollusca	Firmicutes	cytoplasmic vesicle [GO:0031410]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]; single fertilization [GO:0007338]	nucleoside deoxyribosyltransferase activity [GO:0050144]	single fertilization [GO:0007338]		cytoplasmic vesicle [GO:0031410]		NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; transferase activity [GO:0016740]	nucleoside deoxyribosyltransferase activity [GO:0050144]
d3zxhb__d1f82a___1	Metazoa		Chordata	Firmicutes	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	negative regulation of neurotransmitter secretion [GO:0046929]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	lipid binding [GO:0008289]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d3zxra2_d2g5hb2__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]; regulation of translational fidelity [GO:0006450]; translation [GO:0006412]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	regulation of translational fidelity [GO:0006450]; translation [GO:0006412]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [GO:0050567]
d3zxrc2_d4z9mf2__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; phosphocreatine biosynthetic process [GO:0046314]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; phosphocreatine biosynthetic process [GO:0046314]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3zxrd2_d3l2fk2__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	
d3zxre2_d1crkc2__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; phosphocreatine biosynthetic process [GO:0046314]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	phosphocreatine biosynthetic process [GO:0046314]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d3zxrf1_d2glsd1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d3zxva2_d1htoi2__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3zxva2_d3l2da2__1		Metazoa	Actinobacteria	Annelida	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; phosphocreatine biosynthetic process [GO:0046314]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	phosphocreatine biosynthetic process [GO:0046314]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]
d3zxvb1_d1f1hl1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d3zxvb2_d1htod2__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3zxve1_d1htqa1__1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]
d3zxwa1_d1rsce2__1			Cyanobacteria	Cyanobacteria		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; reductive pentose-phosphate cycle [GO:0019253]		reductive pentose-phosphate cycle [GO:0019253]				monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3zxwb__d1burv___1			Cyanobacteria									
d3zxwf__d1ir1s___1		Viridiplantae	Cyanobacteria	Streptophyta		chloroplast [GO:0009507]; monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]; carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		carbon fixation [GO:0015977]; photorespiration [GO:0009853]; photosynthesis [GO:0015979]		chloroplast [GO:0009507]		monooxygenase activity [GO:0004497]; ribulose-bisphosphate carboxylase activity [GO:0016984]
d3zyda1_d3tlob___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	cysteine-type endopeptidase activity [GO:0004197]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d3zyea1_d5hgga___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	serine-type endopeptidase activity [GO:0004252]
d3zyfc__d3jqxa___1			Proteobacteria	Firmicutes	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	extracellular region [GO:0005576]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]; collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	collagen metabolic process [GO:0032963]; pathogenesis [GO:0009405]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	extracellular region [GO:0005576]	carbohydrate binding [GO:0030246]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; tripeptidase activity [GO:0034701]; zinc ion binding [GO:0008270]
d3zyka1_d3g2sa___1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]; 1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]; axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]; cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	cellular protein metabolic process [GO:0044267]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; protein localization [GO:0008104]; protein localization to cell surface [GO:0034394]; protein localization to ciliary membrane [GO:1903441]; retrograde transport, endosome to Golgi [GO:0042147]; toxin transport [GO:1901998]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]	1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]	ADP-ribosylation factor binding [GO:0030306]; protein heterodimerization activity [GO:0046982]
d3zykb2_d1yd8g1__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]; 1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]; axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	axonogenesis [GO:0007409]; clathrin coat assembly [GO:0048268]; clathrin-dependent endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; endocytosis [GO:0006897]; iron ion homeostasis [GO:0055072]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of axonogenesis [GO:0050772]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neuron death [GO:1901216]; positive regulation of synaptic vesicle clustering [GO:2000809]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle transport [GO:1902803]; regulation of terminal button organization [GO:2000331]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle maturation [GO:0016188]; vesicle budding from membrane [GO:0006900]; vesicle cargo loading [GO:0035459]; vesicle-mediated transport [GO:0016192]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	clathrin-coated pit [GO:0005905]; clathrin-coated vesicle [GO:0030136]; endosome [GO:0005768]; extrinsic component of presynaptic endocytic zone membrane [GO:0098894]; Golgi apparatus [GO:0005794]; intrinsic component of membrane [GO:0031224]; neurofibrillary tangle [GO:0097418]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; parallel fiber to Purkinje cell synapse [GO:0098688]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	1-phosphatidylinositol binding [GO:0005545]; clathrin binding [GO:0030276]; clathrin heavy chain binding [GO:0032050]; identical protein binding [GO:0042802]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; SH3 domain binding [GO:0017124]; SNARE binding [GO:0000149]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d3zyra__d3pjqa2__1	Viridiplantae		Streptophyta		carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]		pathogenesis [GO:0009405]			carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	exo-alpha-sialidase activity [GO:0004308]
d3zyrb__d2a3wm___1	Viridiplantae	Metazoa	Streptophyta	Chordata	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]
d3zywa1_d4e8eb1__1	Metazoa	Metazoa	Chordata	Arthropoda	cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; [2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]	transferase activity [GO:0016740]	[2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]		cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]		electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]	transferase activity [GO:0016740]
d3zywb1_d4j57f___1	Metazoa		Chordata	Apicomplexa	cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]; [2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]	cell [GO:0005623]; cytosol [GO:0005829]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	[2Fe-2S] cluster assembly [GO:0044571]; cell redox homeostasis [GO:0045454]; cellular iron ion homeostasis [GO:0006879]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; regulation of the force of heart contraction [GO:0002026]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cell cortex [GO:0005938]; cytosol [GO:0005829]; dendrite [GO:0030425]; nucleus [GO:0005634]; Z disc [GO:0030018]	cell [GO:0005623]; cytosol [GO:0005829]	electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; iron-sulfur cluster binding [GO:0051536]; metal ion binding [GO:0046872]; protein disulfide oxidoreductase activity [GO:0015035]; protein kinase C binding [GO:0005080]; RNA binding [GO:0003723]	protein disulfide oxidoreductase activity [GO:0015035]
d3zz6a1_d2zeba___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d3zz8a1_d1zmna___1		Metazoa		Chordata	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d3zzfa__d1uvdc___1	Fungi		Ascomycota		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]		arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]	
d3zzfc__d2j0xb1__1	Fungi		Ascomycota	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]; homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]	arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]	homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]	aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]
d3zzgb__d2hmfa1__1	Fungi		Ascomycota	Euryarchaeota	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]; homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]	homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]	aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]
d3zzgd__d1uvda___1	Fungi		Ascomycota		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]		arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]	
d3zzhb__d4ndra___1	Fungi		Ascomycota	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; molybdenum ion binding [GO:0030151]; nutrient reservoir activity [GO:0045735]	arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]	molybdenum ion binding [GO:0030151]; nutrient reservoir activity [GO:0045735]
d3zzhc__d2hmfd1__1	Fungi		Ascomycota	Euryarchaeota	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]; homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]	homoserine biosynthetic process [GO:0009090]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytosol [GO:0005829]	acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]	aspartate kinase activity [GO:0004072]; ATP binding [GO:0005524]
d3zzhc__d4f6ta___1	Fungi		Ascomycota	Proteobacteria	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]; arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; molybdenum ion binding [GO:0030151]; nutrient reservoir activity [GO:0045735]	arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]; regulation of transcription, DNA-templated [GO:0006355]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	acetyl-CoA:L-glutamate N-acetyltransferase activity [GO:0004042]; acetylglutamate kinase activity [GO:0003991]; arginine binding [GO:0034618]; ATP binding [GO:0005524]; N-acetyl-gamma-glutamyl-phosphate reductase activity [GO:0003942]; NAD binding [GO:0051287]; protein dimerization activity [GO:0046983]	molybdenum ion binding [GO:0030151]; nutrient reservoir activity [GO:0045735]
d3zzja__d1ohwc___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]	(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]
d3zzna1_d3aogc2__1			Deinococcus-Thermus	Deinococcus-Thermus	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	glycolytic process [GO:0006096]	cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d3zzna2_d4ajic2__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d3zznb2_d3gvhd2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]
d3zznc1_d4wleb1__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	L-lactate dehydrogenase activity [GO:0004459]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d3zznd2_d3vkue2__1			Deinococcus-Thermus		cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]		glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	
d3zzqd__d1c9si___1			Firmicutes	Firmicutes	RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]; DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]	DNA-templated transcription, termination [GO:0006353]; regulation of transcription, DNA-templated [GO:0006355]			RNA binding [GO:0003723]	identical protein binding [GO:0042802]; RNA binding [GO:0003723]
d3zzxa__d5v3qa1__1	Metazoa	Metazoa	Arthropoda	Chordata	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]; cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; interleukin-12-mediated signaling pathway [GO:0035722]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; oxidation-reduction process [GO:0055114]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	protein disulfide oxidoreductase activity [GO:0015035]	glutathione dehydrogenase (ascorbate) activity [GO:0045174]; glutathione transferase activity [GO:0004364]; methylarsonate reductase activity [GO:0050610]; oxidoreductase activity [GO:0016491]
d3zzyb__d4cq1c2__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]; fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	fibroblast growth factor receptor signaling pathway [GO:0008543]; IRES-dependent viral translational initiation [GO:0075522]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of RNA splicing [GO:0033119]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]	poly-pyrimidine tract binding [GO:0008187]; pre-mRNA binding [GO:0036002]; RNA binding [GO:0003723]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]
d3zzza__d5iqqb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; RNA binding [GO:0003723]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 14-3-3 protein binding [GO:0071889]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]; meiotic cell cycle [GO:0051321]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; snRNA catabolic process [GO:0016076]		meiotic cell cycle [GO:0051321]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; snRNA catabolic process [GO:0016076]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]	RNA binding [GO:0003723]	14-3-3 protein binding [GO:0071889]; pre-mRNA intronic binding [GO:0097157]; RNA binding [GO:0003723]; single-stranded RNA binding [GO:0003727]; snRNA binding [GO:0017069]
d43c9a__d1oarh___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	adaptive immune response [GO:0002250]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d43c9a__d2cdfb2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d43c9e__d1sjea1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]
d43c9f__d5fyle2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]; actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	actin filament reorganization [GO:0090527]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; evasion or tolerance by virus of host immune response [GO:0030683]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of plasma membrane raft polarization [GO:1903908]; positive regulation of receptor clustering [GO:1903911]; viral protein processing [GO:0019082]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	host cell endosome membrane [GO:0044175]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; structural molecule activity [GO:0005198]
d43c9g__d1mhpx___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	activation of MAPK activity [GO:0000187]; cell chemotaxis [GO:0060326]; cellular extravasation [GO:0045123]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; neuron projection morphogenesis [GO:0048812]; neutrophil chemotaxis [GO:0030593]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; vasodilation [GO:0042311]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	acrosomal vesicle [GO:0001669]; basal part of cell [GO:0045178]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha1-beta1 complex [GO:0034665]; membrane [GO:0016020]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; perikaryon [GO:0043204]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; metal ion binding [GO:0046872]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]
d43c9g__d3ftgb1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d43c9h__d4f33e2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d43caa__d1h3ua2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d43cab__d1bjma2__1	Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d43cac__d1axtl1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d43cae__d3durc___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d43caf__d2ak4d2__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d456ca__d1hfca___1	Metazoa	Metazoa	Chordata	Chordata	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; leukocyte migration [GO:0050900]; positive regulation of protein complex assembly [GO:0031334]; proteolysis [GO:0006508]; viral process [GO:0016032]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d456cb__d1qjia___1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cortical granule [GO:0060473]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; aspartic-type peptidase activity [GO:0070001]; glutamic-type peptidase activity [GO:0070002]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]; cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]	bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cellular protein metabolic process [GO:0044267]; collagen catabolic process [GO:0030574]; endochondral ossification [GO:0001958]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; growth plate cartilage development [GO:0003417]; proteolysis [GO:0006508]; response to amyloid-beta [GO:1904645]	cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]	extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	cortical granule [GO:0060473]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]	aspartic-type peptidase activity [GO:0070001]; glutamic-type peptidase activity [GO:0070002]; metalloendopeptidase activity [GO:0004222]; peptidase activity [GO:0008233]; zinc ion binding [GO:0008270]
d4a0mc__d4x4la___1	Viridiplantae	Metazoa	Streptophyta	Chordata	chloroplast [GO:0009507]; betaine-aldehyde dehydrogenase activity [GO:0008802]; cellular aldehyde metabolic process [GO:0006081]; glycine betaine biosynthetic process from choline [GO:0019285]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; androgen binding [GO:0005497]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; GTPase activator activity [GO:0005096]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]; cellular aldehyde metabolic process [GO:0006081]; ethanol oxidation [GO:0006069]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; negative regulation of cold-induced thermogenesis [GO:0120163]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	cellular aldehyde metabolic process [GO:0006081]; glycine betaine biosynthetic process from choline [GO:0019285]	cellular aldehyde metabolic process [GO:0006081]; ethanol oxidation [GO:0006069]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; negative regulation of cold-induced thermogenesis [GO:0120163]; oxidation-reduction process [GO:0055114]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	chloroplast [GO:0009507]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]	betaine-aldehyde dehydrogenase activity [GO:0008802]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; androgen binding [GO:0005497]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; GTPase activator activity [GO:0005096]; NAD binding [GO:0051287]; retinal dehydrogenase activity [GO:0001758]
d4a16c1_d4yx9d___1	Metazoa		Chordata	Proteobacteria	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]; acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]		acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]		anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]		acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]	
d4a1hc1_d1d3sa___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]; cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]; membrane organization [GO:0061024]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	membrane organization [GO:0061024]	vasodilation [GO:0042311]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]	extracellular region [GO:0005576]	cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d4a1ma__d3r8kb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; heme metabolic process [GO:0042168]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; negative regulation of mitochondrial membrane potential [GO:0010917]; neutrophil degranulation [GO:0043312]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940]	heme metabolic process [GO:0042168]	negative regulation of mitochondrial membrane potential [GO:0010917]; neutrophil degranulation [GO:0043312]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	heme binding [GO:0020037]	heme binding [GO:0020037]
d4a1ya1_d1sxwa___1	Metazoa	Metazoa	Chordata	Arthropoda	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]; cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]; membrane organization [GO:0061024]	extracellular region [GO:0005576]; histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]; vasodilation [GO:0042311]	membrane organization [GO:0061024]	vasodilation [GO:0042311]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]	extracellular region [GO:0005576]	cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]	histamine binding [GO:0051381]; metal ion binding [GO:0046872]; nitric oxide binding [GO:0070026]; oxidoreductase activity [GO:0016491]
d4a1yb1_d4azma1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]; cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]; membrane organization [GO:0061024]	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]; epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	membrane organization [GO:0061024]	epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]	cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]	fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]
d4a1yc1_d3feka___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]; cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]; membrane organization [GO:0061024]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]; embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	membrane organization [GO:0061024]	embryonic forelimb morphogenesis [GO:0035115]; epidermis development [GO:0008544]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription, DNA-templated [GO:0006355]; retinoic acid biosynthetic process [GO:0002138]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]	cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]	retinal binding [GO:0016918]; retinoic acid binding [GO:0001972]; retinoid binding [GO:0005501]; retinol binding [GO:0019841]
d4a1yc1_d3kffa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]; cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]; membrane organization [GO:0061024]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]; aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	membrane organization [GO:0061024]	aerobic respiration [GO:0009060]; cellular response to lipid [GO:0071396]; energy reserve metabolic process [GO:0006112]; glucose homeostasis [GO:0042593]; heat generation [GO:0031649]; locomotor rhythm [GO:0045475]; mitochondrion morphogenesis [GO:0070584]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of lipid storage [GO:0010888]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of protein kinase B signaling [GO:0051897]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]	cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]	insulin-activated receptor activity [GO:0005009]; pheromone binding [GO:0005550]; small molecule binding [GO:0036094]
d4a25b__d3e1nd___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d4a25c__d1nf6e___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4a25d__d2uw1a___1			Actinobacteria		cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]		cellular iron ion homeostasis [GO:0006879]		cell [GO:0005623]		ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	
d4a2da3_d3pxla2__1	Fungi	Fungi	Basidiomycota	Basidiomycota	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]					copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d4a2ea2_d2ftad___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d4a2ea2_d3t6xa1__1	Fungi	Fungi	Basidiomycota	Basidiomycota	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]					copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d4a2ea3_d2idqa___1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]				periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d4a2fa1_d4l0pb___1	Fungi	Metazoa	Basidiomycota	Chordata	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	adherens junction [GO:0005912]; anchored component of external side of plasma membrane [GO:0031362]; basement membrane [GO:0005604]; caveola [GO:0005901]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]; chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; neurotrophin TRKA receptor binding [GO:0005168]; neurotrophin TRKB receptor binding [GO:0005169]; neurotrophin TRKC receptor binding [GO:0005170]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]; axon guidance [GO:0007411]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to forskolin [GO:1904322]; collateral sprouting [GO:0048668]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; nervous system development [GO:0007399]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell morphogenesis [GO:0022604]; regulation of cell-cell adhesion [GO:0022407]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of microtubule cytoskeleton organization [GO:0070507]; retinal ganglion cell axon guidance [GO:0031290]; synaptic membrane adhesion [GO:0099560]		axon guidance [GO:0007411]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to forskolin [GO:1904322]; collateral sprouting [GO:0048668]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; nervous system development [GO:0007399]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synapse assembly [GO:0051965]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell morphogenesis [GO:0022604]; regulation of focal adhesion assembly [GO:0051893]; regulation of GTPase activity [GO:0043087]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of microtubule cytoskeleton organization [GO:0070507]; retinal ganglion cell axon guidance [GO:0031290]; synaptic membrane adhesion [GO:0099560]		adherens junction [GO:0005912]; anchored component of external side of plasma membrane [GO:0031362]; basement membrane [GO:0005604]; caveola [GO:0005901]; GABA-ergic synapse [GO:0098982]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	chemorepellent activity [GO:0045499]; ephrin receptor binding [GO:0046875]; neurotrophin TRKA receptor binding [GO:0005168]; neurotrophin TRKB receptor binding [GO:0005169]; neurotrophin TRKC receptor binding [GO:0005170]; transmembrane receptor protein tyrosine kinase activator activity [GO:0030297]
d4a2fa1_d5f7ba2__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d4a2fa3_d1tsad___1	Fungi		Basidiomycota		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]						copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	
d4a2ga1_d3t6xb2__1	Fungi	Fungi	Basidiomycota	Basidiomycota	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]					copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d4a2ga2_d5d4jc1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d4a2ga3_d1zdsb1__1	Fungi		Basidiomycota	Proteobacteria	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d4a2ga3_d2eijo1__1	Fungi	Metazoa	Basidiomycota	Chordata	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]; ATP synthesis coupled electron transport [GO:0042773]		ATP synthesis coupled electron transport [GO:0042773]		integral component of membrane [GO:0016021]; mitochondrial inner membrane [GO:0005743]; respiratory chain complex IV [GO:0045277]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d4a2ra1_d3hoja___1			Crenarchaeota		indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]; tryptophan biosynthetic process [GO:0000162]		tryptophan biosynthetic process [GO:0000162]				indole-3-glycerol-phosphate synthase activity [GO:0004425]; phosphoribosylanthranilate isomerase activity [GO:0004640]	
d4a2uc1_d3ryrb1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d4a2ud1_d1runb2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d4a2ud1_d4z07a1__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular smooth muscle cell proliferation [GO:1904706]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	ATP binding [GO:0005524]; calcium channel regulator activity [GO:0005246]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]
d4a2ue1_d4hzfb1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d4a2uf1_d3e6ba1__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d4a2uf2_d2irfk___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cell population proliferation [GO:0008283]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cell population proliferation [GO:0008283]; defense response to virus [GO:0051607]; immune system process [GO:0002376]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; focal adhesion [GO:0005925]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d4a2ug1_d3e6db1__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]		cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	DNA binding [GO:0003677]
d4a2ug1_d5c8wc___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; cofactor metabolic process [GO:0051186]; negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cofactor metabolic process [GO:0051186]; negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]
d4a2uh1_d5k8sa1__1			Actinobacteria	Apicomplexa	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cAMP-dependent protein kinase complex [GO:0005952]; cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP-dependent protein kinase activity [GO:0004691]; cAMP-dependent protein kinase regulator activity [GO:0008603]; nucleotide binding [GO:0000166]; cGMP-mediated signaling [GO:0019934]	negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	cGMP-mediated signaling [GO:0019934]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	cAMP-dependent protein kinase complex [GO:0005952]; cytosol [GO:0005829]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; cAMP-dependent protein kinase activity [GO:0004691]; cAMP-dependent protein kinase regulator activity [GO:0008603]; nucleotide binding [GO:0000166]
d4a34b__d1ogfa___1			Firmicutes	Firmicutes	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]; monosaccharide metabolic process [GO:0005996]	cytosol [GO:0005829]; intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; D-ribose catabolic process [GO:0019303]	monosaccharide metabolic process [GO:0005996]	D-ribose catabolic process [GO:0019303]		cytosol [GO:0005829]	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]	intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d4a34e__d3p13c___1			Firmicutes	Firmicutes	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]; monosaccharide metabolic process [GO:0005996]	cytosol [GO:0005829]; intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; D-ribose catabolic process [GO:0019303]	monosaccharide metabolic process [GO:0005996]	D-ribose catabolic process [GO:0019303]		cytosol [GO:0005829]	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]	intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d4a34f__d1ogfb___1			Firmicutes	Firmicutes	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]; monosaccharide metabolic process [GO:0005996]	cytosol [GO:0005829]; intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; D-ribose catabolic process [GO:0019303]	monosaccharide metabolic process [GO:0005996]	D-ribose catabolic process [GO:0019303]		cytosol [GO:0005829]	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]	intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d4a34h__d1ogee___1			Firmicutes	Firmicutes	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]; monosaccharide metabolic process [GO:0005996]	cytosol [GO:0005829]; intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; D-ribose catabolic process [GO:0019303]	monosaccharide metabolic process [GO:0005996]	D-ribose catabolic process [GO:0019303]		cytosol [GO:0005829]	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]	intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d4a34j__d1ogdd___1			Firmicutes	Firmicutes	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]; monosaccharide metabolic process [GO:0005996]	cytosol [GO:0005829]; intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; D-ribose catabolic process [GO:0019303]	monosaccharide metabolic process [GO:0005996]	D-ribose catabolic process [GO:0019303]		cytosol [GO:0005829]	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]	intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d4a34l__d1ogec___1			Firmicutes	Firmicutes	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]; monosaccharide metabolic process [GO:0005996]	cytosol [GO:0005829]; intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; D-ribose catabolic process [GO:0019303]	monosaccharide metabolic process [GO:0005996]	D-ribose catabolic process [GO:0019303]		cytosol [GO:0005829]	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]	intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d4a34p__d1ogdb___1			Firmicutes	Firmicutes	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]; monosaccharide metabolic process [GO:0005996]	cytosol [GO:0005829]; intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]; D-ribose catabolic process [GO:0019303]	monosaccharide metabolic process [GO:0005996]	D-ribose catabolic process [GO:0019303]		cytosol [GO:0005829]	isomerase activity [GO:0016853]; monosaccharide binding [GO:0048029]	intramolecular lyase activity [GO:0016872]; intramolecular transferase activity [GO:0016866]; monosaccharide binding [GO:0048029]
d4a3ha__d1j0yd2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]	amylopectin maltohydrolase activity [GO:0102229]; beta-amylase activity [GO:0016161]; metal ion binding [GO:0046872]; starch binding [GO:2001070]
d4a3ra2_d2ptya1__1			Firmicutes		cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]; sporulation resulting in formation of a cellular spore [GO:0030435]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]; sporulation resulting in formation of a cellular spore [GO:0030435]	glycolytic process [GO:0006096]	cell surface [GO:0009986]; extracellular region [GO:0005576]; phosphopyruvate hydratase complex [GO:0000015]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; phosphopyruvate hydratase complex [GO:0000015]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]	magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d4a46d__d3k7rh___1		Fungi	Cyanobacteria	Ascomycota	copper ion binding [GO:0005507]; metal ion transport [GO:0030001]	cell [GO:0005623]; cytosol [GO:0005829]; copper chaperone activity [GO:0016531]; cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]	metal ion transport [GO:0030001]	cellular copper ion homeostasis [GO:0006878]; cellular iron ion homeostasis [GO:0006879]; cellular response to oxidative stress [GO:0034599]; copper ion transport [GO:0006825]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytosol [GO:0005829]	copper ion binding [GO:0005507]	copper chaperone activity [GO:0016531]
d4a47b__d1fe4a___1		Metazoa	Cyanobacteria	Chordata	copper ion binding [GO:0005507]; metal ion transport [GO:0030001]	cell [GO:0005623]; cytosol [GO:0005829]; ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper ion binding [GO:0005507]; copper-dependent protein binding [GO:0032767]; metallochaperone activity [GO:0016530]; cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]	metal ion transport [GO:0030001]	cellular copper ion homeostasis [GO:0006878]; copper ion export [GO:0060003]; copper ion transport [GO:0006825]; negative regulation of apoptotic process [GO:0043066]; response to oxidative stress [GO:0006979]		cell [GO:0005623]; cytosol [GO:0005829]	copper ion binding [GO:0005507]	ATPase binding [GO:0051117]; copper chaperone activity [GO:0016531]; copper-dependent protein binding [GO:0032767]; copper ion binding [GO:0005507]; metallochaperone activity [GO:0016530]
d4a49b__d2yhof1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]; ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]; cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cytoskeletal protein binding [GO:0008092]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; cholesterol homeostasis [GO:0042632]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]; ubiquitin-dependent protein catabolic process [GO:0006511]	cellular protein modification process [GO:0006464]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; ubiquitin-dependent protein catabolic process [GO:0006511]	cholesterol homeostasis [GO:0042632]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; protein-containing complex [GO:0032991]; ubiquitin ligase complex [GO:0000151]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-protein transferase activity [GO:0004842]	cytoskeletal protein binding [GO:0008092]; metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]
d4a4ia__d5vl1d1__1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; miRNA catabolic process [GO:0010587]; pre-miRNA processing [GO:0031054]; RNA 3'-end processing [GO:0031123]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	miRNA catabolic process [GO:0010587]; pre-miRNA processing [GO:0031054]; RNA 3'-end processing [GO:0031123]	lysyl-tRNA aminoacylation [GO:0006430]	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d4a4ib__d5elna1__1	Metazoa		Chordata	Apicomplexa	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; miRNA catabolic process [GO:0010587]; pre-miRNA processing [GO:0031054]; RNA 3'-end processing [GO:0031123]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]	miRNA catabolic process [GO:0010587]; pre-miRNA processing [GO:0031054]; RNA 3'-end processing [GO:0031123]	lysyl-tRNA aminoacylation [GO:0006430]	cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]	RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; nucleic acid binding [GO:0003676]
d4a4oa__d3o2mb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]; anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	axon [GO:0030424]; axonal growth cone [GO:0044295]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic growth cone [GO:0044294]; dentate gyrus mossy fiber [GO:0044302]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]; identical protein binding [GO:0042802]; JUN kinase binding [GO:0008432]; kinesin binding [GO:0019894]; MAP-kinase scaffold activity [GO:0005078]; mitogen-activated protein kinase kinase binding [GO:0031434]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]; JUN phosphorylation [GO:0007258]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; positive regulation of endocytosis [GO:0045807]; positive regulation of JNK cascade [GO:0046330]; receptor-mediated endocytosis [GO:0006898]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564]; regulation of JNK cascade [GO:0046328]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; centrosome cycle [GO:0007098]; ciliary basal body-plasma membrane docking [GO:0097711]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear envelope disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cytokinesis [GO:0032465]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; signal transduction involved in G2 DNA damage checkpoint [GO:0072425]; sister chromatid cohesion [GO:0007062]; synaptonemal complex disassembly [GO:0070194]; ubiquitin-dependent protein catabolic process [GO:0006511]	JUN phosphorylation [GO:0007258]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; positive regulation of endocytosis [GO:0045807]; positive regulation of JNK cascade [GO:0046330]; receptor-mediated endocytosis [GO:0006898]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564]; regulation of JNK cascade [GO:0046328]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192]	cell [GO:0005623]; centriolar satellite [GO:0034451]; centriole [GO:0005814]; centrosome [GO:0005813]; chromatin [GO:0000785]; condensed nuclear chromosome outer kinetochore [GO:0000942]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; kinetochore [GO:0000776]; microtubule cytoskeleton [GO:0015630]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spindle [GO:0005819]; spindle midzone [GO:0051233]; spindle pole [GO:0000922]; synaptonemal complex [GO:0000795]	axon [GO:0030424]; axonal growth cone [GO:0044295]; cell body [GO:0044297]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic growth cone [GO:0044294]; dentate gyrus mossy fiber [GO:0044302]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202]	anaphase-promoting complex binding [GO:0010997]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; microtubule binding [GO:0008017]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]	identical protein binding [GO:0042802]; JUN kinase binding [GO:0008432]; kinesin binding [GO:0019894]; MAP-kinase scaffold activity [GO:0005078]; mitogen-activated protein kinase kinase binding [GO:0031434]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase binding [GO:0019901]
d4a4pa__d4jmia1__1	Metazoa	Metazoa	Chordata	Chordata	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; lipid binding [GO:0008289]; establishment of epithelial cell polarity [GO:0090162]; regulation of ARF protein signal transduction [GO:0032012]; regulation of cell adhesion [GO:0030155]; vesicle-mediated transport [GO:0016192]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ARF guanyl-nucleotide exchange factor activity [GO:0005086]; inositol 1,4,5 trisphosphate binding [GO:0070679]; lipid binding [GO:0008289]; actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; regulation of ARF protein signal transduction [GO:0032012]	establishment of epithelial cell polarity [GO:0090162]; regulation of ARF protein signal transduction [GO:0032012]; regulation of cell adhesion [GO:0030155]; vesicle-mediated transport [GO:0016192]	actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; regulation of ARF protein signal transduction [GO:0032012]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]	adherens junction [GO:0005912]; bicellular tight junction [GO:0005923]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi membrane [GO:0000139]; growth cone [GO:0030426]; membrane [GO:0016020]; plasma membrane [GO:0005886]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; lipid binding [GO:0008289]	ARF guanyl-nucleotide exchange factor activity [GO:0005086]; inositol 1,4,5 trisphosphate binding [GO:0070679]; lipid binding [GO:0008289]
d4a4qa__d1fq6a___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]; autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]		autophagy [GO:0006914]; cellular response to starvation [GO:0009267]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; lysosomal microautophagy [GO:0016237]; macroautophagy [GO:0016236]; pexophagy [GO:0000425]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; vacuolar protein processing [GO:0006624]		endoplasmic reticulum [GO:0005783]; fungal-type vacuole [GO:0000324]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; disordered domain specific binding [GO:0097718]; oligosaccharide binding [GO:0070492]; peptidase activity [GO:0008233]
d4a4qb__d5p4ua___1		Fungi		Ascomycota	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d4a5ga__d5cida___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d4a5mb__d1sd6a___1			Firmicutes	Firmicutes	DNA binding [GO:0003677]	cytoplasm [GO:0005737]; DNA binding [GO:0003677]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]	DNA binding [GO:0003677]	DNA binding [GO:0003677]
d4a5mg__d1kywf1__1		Viridiplantae	Firmicutes	Streptophyta	DNA binding [GO:0003677]	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]; lignin biosynthetic process [GO:0009809]		lignin biosynthetic process [GO:0009809]			DNA binding [GO:0003677]	caffeate O-methyltransferase activity [GO:0047763]; protein dimerization activity [GO:0046983]
d4a5oc1_d1llqa2__1		Metazoa	Proteobacteria	Nematoda (roundworms)	cytosol [GO:0005829]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	mitochondrial matrix [GO:0005759]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]		cytosol [GO:0005829]	mitochondrial matrix [GO:0005759]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; metal ion binding [GO:0046872]; NAD binding [GO:0051287]; oxaloacetate decarboxylase activity [GO:0008948]
d4a5oc2_d2b36a___1			Proteobacteria	Actinobacteria	cytosol [GO:0005829]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d4a5oc2_d2hjrb1__1			Proteobacteria	Apicomplexa	cytosol [GO:0005829]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytosol [GO:0005829]		methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d4a5xa__d1wr0a1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; condensed nuclear chromosome [GO:0000794]; early endosome [GO:0005769]; endomembrane system [GO:0012505]; ESCRT III complex [GO:0000815]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nuclear matrix [GO:0016363]; identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; cell division [GO:0051301]; endosome transport via multivesicular body sorting pathway [GO:0032509]; ESCRT III complex disassembly [GO:1904903]; gene silencing [GO:0016458]; late endosome to vacuole transport [GO:0045324]; midbody abscission [GO:0061952]; mitotic chromosome condensation [GO:0007076]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; negative regulation of cell cycle [GO:0045786]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleus organization [GO:0006997]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; vesicle-mediated transport [GO:0016192]; viral budding via host ESCRT complex [GO:0039702]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; late endosome membrane [GO:0031902]; nucleus [GO:0005634]; spindle pole [GO:0000922]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]; cholesterol transport [GO:0030301]; endosomal transport [GO:0016197]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ESCRT III complex disassembly [GO:1904903]; late endosomal microautophagy [GO:0061738]; macroautophagy [GO:0016236]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; negative regulation of cell death [GO:0060548]; negative regulation of exosomal secretion [GO:1903542]; nucleus organization [GO:0006997]; positive regulation of centriole elongation [GO:1903724]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of viral life cycle [GO:1903902]; positive regulation of viral process [GO:0048524]; positive regulation of viral release from host cell [GO:1902188]; potassium ion transport [GO:0006813]; protein depolymerization [GO:0051261]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; regulation of viral process [GO:0050792]; response to lipid [GO:0033993]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; vacuole organization [GO:0007033]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]	cell division [GO:0051301]; endosome transport via multivesicular body sorting pathway [GO:0032509]; ESCRT III complex disassembly [GO:1904903]; gene silencing [GO:0016458]; late endosome to vacuole transport [GO:0045324]; midbody abscission [GO:0061952]; mitotic chromosome condensation [GO:0007076]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; negative regulation of cell cycle [GO:0045786]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleus organization [GO:0006997]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; vesicle-mediated transport [GO:0016192]; viral budding via host ESCRT complex [GO:0039702]	cholesterol transport [GO:0030301]; endosomal transport [GO:0016197]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ESCRT III complex disassembly [GO:1904903]; late endosomal microautophagy [GO:0061738]; macroautophagy [GO:0016236]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; negative regulation of cell death [GO:0060548]; negative regulation of exosomal secretion [GO:1903542]; nucleus organization [GO:0006997]; positive regulation of centriole elongation [GO:1903724]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of viral life cycle [GO:1903902]; positive regulation of viral process [GO:0048524]; positive regulation of viral release from host cell [GO:1902188]; potassium ion transport [GO:0006813]; protein depolymerization [GO:0051261]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; regulation of viral process [GO:0050792]; response to lipid [GO:0033993]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; vacuole organization [GO:0007033]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]; viral release from host cell [GO:0019076]	cell [GO:0005623]; condensed nuclear chromosome [GO:0000794]; early endosome [GO:0005769]; endomembrane system [GO:0012505]; ESCRT III complex [GO:0000815]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]; multivesicular body [GO:0005771]; nuclear matrix [GO:0016363]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; Flemming body [GO:0090543]; late endosome membrane [GO:0031902]; nucleus [GO:0005634]; spindle pole [GO:0000922]	identical protein binding [GO:0042802]; metallopeptidase activity [GO:0008237]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein homodimerization activity [GO:0042803]
d4a63a1_d4loea___1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d4a63c1_d1a02n2__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d4a63e1_d1nfkb2__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	activation of MAPK activity [GO:0000187]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; kidney development [GO:0001822]; mismatch repair [GO:0006298]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein tetramerization [GO:0051262]; regulation of apoptotic process [GO:0042981]; regulation of gene expression [GO:0010468]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]; viral process [GO:0016032]	apoptotic process [GO:0006915]; cellular response to angiotensin [GO:1904385]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymph node development [GO:0048535]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cytokine production [GO:0001818]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]	cell junction [GO:0030054]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; metal ion binding [GO:0046872]; p53 binding [GO:0002039]; protein kinase binding [GO:0019901]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	actinin binding [GO:0042805]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; heat shock protein binding [GO:0031072]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription coactivator binding [GO:0001225]; sequence-specific DNA binding [GO:0043565]; transcription regulatory region DNA binding [GO:0044212]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d4a68a3_d2pp7a2__1			Firmicutes	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	sporulation resulting in formation of a cellular spore [GO:0030435]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d4a6ac__d2bsya1__1			Actinobacteria		dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUTP metabolic process [GO:0046080]			dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]
d4a6ac__d3ehwa___1		Metazoa	Actinobacteria	Chordata	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]; DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase-containing small molecule interconversion [GO:0015949]		extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; RNA binding [GO:0003723]
d4a6ag__d4apzp___1			Actinobacteria	Firmicutes	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d4a6ca__d3tneb___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	extracellular region [GO:0005576]; aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d4a6cb__d4q1ya___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA recombination [GO:0006310]; entry into host cell [GO:0030260]; establishment of integrated proviral latency [GO:0075713]; fusion of virus membrane with host plasma membrane [GO:0019064]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; nuclear transport [GO:0051169]; RNA-dependent DNA biosynthetic process [GO:0006278]; suppression by virus of host gene expression [GO:0039657]; uncoating of virus [GO:0019061]; viral genome integration into host DNA [GO:0044826]; viral genome packaging [GO:0019072]; viral life cycle [GO:0019058]; viral penetration into host nucleus [GO:0075732]; virion assembly [GO:0019068]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; integrase activity [GO:0008907]; lipid binding [GO:0008289]; peptidase activity [GO:0008233]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d4a6ga1_d1tkkh2__1			Actinobacteria	Firmicutes	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]; cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]	menaquinone biosynthetic process [GO:0009234]	cell wall macromolecule catabolic process [GO:0016998]; cell wall organization [GO:0071555]			hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	metal ion binding [GO:0046872]; racemase and epimerase activity, acting on amino acids and derivatives [GO:0016855]
d4a6gd2_d5ohgb2__1			Actinobacteria	Proteobacteria	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; menaquinone biosynthetic process [GO:0009234]	cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]; glycolytic process [GO:0006096]	menaquinone biosynthetic process [GO:0009234]	glycolytic process [GO:0006096]		cell surface [GO:0009986]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; phosphopyruvate hydratase complex [GO:0000015]	hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]	identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphopyruvate hydratase activity [GO:0004634]
d4a6lb__d4y7aa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d4a6lc__d3sjoa___1	Metazoa		Chordata		extracellular region [GO:0005576]; extracellular space [GO:0005615]; identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	defense response [GO:0006952]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	identical protein binding [GO:0042802]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d4a6sa__d5ofib___1			Proteobacteria	Proteobacteria	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]		carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d4a6sc__d2j1tb___1			Proteobacteria	Firmicutes	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	carbohydrate metabolic process [GO:0005975]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]		carbohydrate binding [GO:0030246]	metal ion binding [GO:0046872]
d4a6tb__d1kusa___1			Proteobacteria		adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]						adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]	
d4a6ya1_d1qacb___1		Metazoa		Chordata		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; immunoglobulin production [GO:0002377]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		blood microparticle [GO:0072562]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex [GO:0019814]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]
d4a6ya2_d4l29n1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4a6ya2_d4nc0b1__1												
d4a71a__d5sxwa2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d4a72d__d3dr4d1__1			Proteobacteria	Proteobacteria	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]	GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase activity [GO:0102933]; O antigen biosynthetic process [GO:0009243]		O antigen biosynthetic process [GO:0009243]			adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]	GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase activity [GO:0102933]
d4a72d__d4y0ib___1		Metazoa	Proteobacteria	Chordata	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]		behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]		4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]	(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]
d4a73a1_d1m6wb2__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	glycolytic process [GO:0006096]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	L-lactate dehydrogenase activity [GO:0004459]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]
d4a73b1_d5js6a1__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]; estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	glycolytic process [GO:0006096]	estrogen biosynthetic process [GO:0006703]; steroid catabolic process [GO:0006706]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	L-lactate dehydrogenase activity [GO:0004459]	estradiol 17-beta-dehydrogenase activity [GO:0004303]; identical protein binding [GO:0042802]; testosterone 17-beta-dehydrogenase (NADP+) activity [GO:0047045]
d4a73b2_d3pqdc2__1			Deinococcus-Thermus	Firmicutes	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d4a73b2_d4i9hd2__1		Metazoa	Deinococcus-Thermus	Chordata	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d4a73c1_d1scua1__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]; cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]; nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]	nucleoside triphosphate biosynthetic process [GO:0009142]; protein autophosphorylation [GO:0046777]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; succinate-CoA ligase complex (ADP-forming) [GO:0009361]	L-lactate dehydrogenase activity [GO:0004459]	cofactor binding [GO:0048037]; nucleoside diphosphate kinase activity [GO:0004550]; nucleotide binding [GO:0000166]; succinate-CoA ligase (ADP-forming) activity [GO:0004775]
d4a73c2_d1sowb2__1			Deinococcus-Thermus	Apicomplexa	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]		L-lactate dehydrogenase activity [GO:0004459]	L-lactate dehydrogenase activity [GO:0004459]
d4a73d1_d1qorb2__1			Deinococcus-Thermus	Proteobacteria	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; NADPH:quinone reductase activity [GO:0003960]; zinc ion binding [GO:0008270]; cellular response to oxidative stress [GO:0034599]	glycolytic process [GO:0006096]	cellular response to oxidative stress [GO:0034599]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	L-lactate dehydrogenase activity [GO:0004459]	NADPH:quinone reductase activity [GO:0003960]; zinc ion binding [GO:0008270]
d4a75e1_d5vl1b1__1	Metazoa		Chordata	Actinobacteria	nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]; lysyl-tRNA aminoacylation [GO:0006430]		lysyl-tRNA aminoacylation [GO:0006430]		cytoplasm [GO:0005737]	nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; lysine-tRNA ligase activity [GO:0004824]; magnesium ion binding [GO:0000287]; nucleic acid binding [GO:0003676]
d4a75g1_d1q46a2__1	Metazoa	Fungi	Chordata	Ascomycota	nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 2 complex [GO:0005850]; eukaryotic translation initiation factor 2B complex [GO:0005851]; multi-eIF complex [GO:0043614]; ribosome [GO:0005840]; ribosome binding [GO:0043022]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; translational initiation [GO:0006413]		formation of translation preinitiation complex [GO:0001731]; translational initiation [GO:0006413]		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; eukaryotic 48S preinitiation complex [GO:0033290]; eukaryotic translation initiation factor 2B complex [GO:0005851]; eukaryotic translation initiation factor 2 complex [GO:0005850]; multi-eIF complex [GO:0043614]; ribosome [GO:0005840]	nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]	ribosome binding [GO:0043022]; translation initiation factor activity [GO:0003743]
d4a76a__d2vw9a___1	Metazoa		Chordata	Proteobacteria	nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]	single-stranded DNA binding [GO:0003697]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]		DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]			nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]	single-stranded DNA binding [GO:0003697]
d4a76c__d2nzoa1__1	Metazoa		Chordata	Firmicutes	nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]	cytoplasm [GO:0005737]; tRNA binding [GO:0000049]; protein transport [GO:0015031]		protein transport [GO:0015031]		cytoplasm [GO:0005737]	nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]	tRNA binding [GO:0000049]
d4a78a__d1ub2a1__1	Fungi		Ascomycota	Cyanobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d4a7aa2_d3cpjg3__1	Metazoa	Fungi	Chordata	Ascomycota	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	GTPase activator activity [GO:0005096]; Rab GDP-dissociation inhibitor activity [GO:0005093]; Rab GTPase binding [GO:0017137]
d4a7ib__d1p03a___1	Metazoa		Chordata	Proteobacteria	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d4a7ma__d1w4wa___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	extracellular region [GO:0005576]; vacuole [GO:0005773]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d4a7qa__d3gzog___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d4a7qf__d2z7wb___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interspecies interaction between organisms [GO:0044419]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cytokine production [GO:0001817]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; superoxide dismutase activity [GO:0004784]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d4a7sa__d1sdyb___1	Metazoa	Fungi	Chordata	Ascomycota	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]; age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	age-dependent response to reactive oxygen species involved in chronological cell aging [GO:0001320]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; fungal-type cell wall organization [GO:0031505]; negative regulation of cellular respiration [GO:1901856]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0036091]; protein stabilization [GO:0050821]; removal of superoxide radicals [GO:0019430]; superoxide metabolic process [GO:0006801]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; superoxide dismutase activity [GO:0004784]
d4a7uf__d3gtvk___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d4a7va__d1hl5i___1	Metazoa	Metazoa	Chordata	Chordata	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]
d4a80a__d2ns9a1__1	Viridiplantae		Streptophyta	Crenarchaeota	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]		abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	
d4a82a2_d5hkkj2__1			Firmicutes	Firmicutes	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]		ATP synthesis coupled proton transport [GO:0015986]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATPase activity [GO:0016887]; ATPase-coupled transmembrane transporter activity [GO:0042626]; ATP binding [GO:0005524]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d4a84a__d4bk7a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d4a87a__d2b1xc2__1	Viridiplantae		Streptophyta	Actinobacteria	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	cellular metabolic process [GO:0044237]	cytoplasm [GO:0005737]		abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]
d4a8ga__d5aewe2__1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]	cytoplasm [GO:0005737]		abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d4a8xa1_d1rkja1__1	Metazoa	Metazoa	Arthropoda	Chordata	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]; nucleic acid binding [GO:0003676]; apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transposition, DNA-mediated [GO:0000335]; regulation of autophagy [GO:0010506]; RNA splicing [GO:0008380]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; ribonucleoprotein complex [GO:1990904]; RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]	apoptotic process [GO:0006915]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transposition, DNA-mediated [GO:0000335]; regulation of autophagy [GO:0010506]; RNA splicing [GO:0008380]		catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; precatalytic spliceosome [GO:0071011]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; ribonucleoprotein complex [GO:1990904]	nucleic acid binding [GO:0003676]	RNA binding [GO:0003723]; telomeric DNA binding [GO:0042162]
d4a8za1_d4azrb1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]; cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]; membrane organization [GO:0061024]	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]; epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	membrane organization [GO:0061024]	epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]	cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]	fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]
d4a8za1_d4os8a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]; cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]; membrane organization [GO:0061024]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]; fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]; cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	membrane organization [GO:0061024]	cyclooxygenase pathway [GO:0019371]; prostaglandin biosynthetic process [GO:0001516]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]	endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nuclear membrane [GO:0031965]; perinuclear region of cytoplasm [GO:0048471]; rough endoplasmic reticulum [GO:0005791]	cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]	fatty acid binding [GO:0005504]; prostaglandin-D synthase activity [GO:0004667]; retinoid binding [GO:0005501]
d4a9ea__d5uesa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]
d4a9fb__d5fe1a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]
d4a9fc__d5fe3b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]
d4a9hb__d5eguc___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]
d4a9hc__d5fe4b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]
d4a9ja__d5pe6a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	nucleus [GO:0005634]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d4a9mb__d4a9kb___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d4a9mc__d5v84b___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	CERF complex [GO:0090537]; nucleus [GO:0005634]; apoptotic DNA fragmentation [GO:0006309]; ATP-dependent chromatin remodeling [GO:0043044]; cytoskeleton organization [GO:0007010]; cytoskeleton-dependent cytokinesis [GO:0061640]; execution phase of apoptosis [GO:0097194]; vesicle-mediated transport [GO:0016192]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	apoptotic DNA fragmentation [GO:0006309]; ATP-dependent chromatin remodeling [GO:0043044]; cytoskeleton-dependent cytokinesis [GO:0061640]; cytoskeleton organization [GO:0007010]; execution phase of apoptosis [GO:0097194]; vesicle-mediated transport [GO:0016192]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	CERF complex [GO:0090537]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	
d4a9pa__d4cura1__1		Metazoa		Chordata		nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]		chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]		nucleus [GO:0005634]		DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d4a9pc__d2yync___1		Metazoa		Chordata		cytosol [GO:0005829]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]; chromatin binding [GO:0003682]; estrogen response element binding [GO:0034056]; lysine-acetylated histone binding [GO:0070577]; nuclear receptor binding [GO:0016922]; p53 binding [GO:0002039]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]; calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription by RNA polymerase II [GO:0006366]		calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription by RNA polymerase II [GO:0006366]		cytosol [GO:0005829]; nuclear euchromatin [GO:0005719]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perichromatin fibrils [GO:0005726]		chromatin binding [GO:0003682]; estrogen response element binding [GO:0034056]; lysine-acetylated histone binding [GO:0070577]; nuclear receptor binding [GO:0016922]; p53 binding [GO:0002039]; protein kinase activity [GO:0004672]; signaling receptor binding [GO:0005102]; transcription coactivator activity [GO:0003713]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; zinc ion binding [GO:0008270]
d4aa8a__d2qhya___1	Metazoa		Chordata		aspartic-type endopeptidase activity [GO:0004190]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d4aala1_d2c1ua2__1			Proteobacteria		cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]						cytochrome-c peroxidase activity [GO:0004130]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; metal ion binding [GO:0046872]	
d4aayh__d1o7wa1__1			Proteobacteria	Proteobacteria	2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]	dioxygenase activity [GO:0051213]; aromatic compound catabolic process [GO:0019439]		aromatic compound catabolic process [GO:0019439]			2 iron, 2 sulfur cluster binding [GO:0051537]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on diphenols and related substances as donors [GO:0016679]	dioxygenase activity [GO:0051213]
d4ab4a1_d1gvsa___1			Proteobacteria	Proteobacteria	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]					FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]
d4abba__d3proa___1	Metazoa		Chordata	Proteobacteria	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]	digestion [GO:0007586]; proteolysis [GO:0006508]		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	serine-type endopeptidase activity [GO:0004252]
d4abda__d4na8a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d4abfa__d4dg4d___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	digestion [GO:0007586]; proteolysis [GO:0006508]	negative regulation of platelet aggregation [GO:0090331]; negative regulation of serine-type endopeptidase activity [GO:1900004]; negative regulation of thrombin-activated receptor signaling pathway [GO:0070495]; trypsinogen activation [GO:0032023]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; potassium channel inhibitor activity [GO:0019870]; protease binding [GO:0002020]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase inhibitor activity [GO:0004867]; sulfate binding [GO:0043199]; zymogen binding [GO:0035375]
d4abqb__d4q14b___1	Metazoa		Chordata	Proteobacteria	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]		hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydroxyisourate hydrolase activity [GO:0033971]
d4abua__d3q1ed___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	peroxisome [GO:0005777]; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	peroxisome [GO:0005777]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811]; hydroxyisourate hydrolase activity [GO:0033971]
d4abwa__d2noya___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d4ac2a__d3bt0b___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d4ac3a2_d4e6ta1__1			Firmicutes		cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]		glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]	
d4ac4a__d1thcb___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d4ac7a__d4epba___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d4ac7a__d4furd___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d4ac7b__d4z42k___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d4ac9d2_d2ey4c1__1			Euryarchaeota	Euryarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; selenocysteine incorporation [GO:0001514]	snoRNA binding [GO:0030515]; pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	selenocysteine incorporation [GO:0001514]	pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	snoRNA binding [GO:0030515]
d4ac9d4_d1he8b___1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; selenocysteine incorporation [GO:0001514]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	selenocysteine incorporation [GO:0001514]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d4acab2_d3cw2f2__1			Euryarchaeota	Crenarchaeota	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; selenocysteine incorporation [GO:0001514]	cytosol [GO:0005829]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]; formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	selenocysteine incorporation [GO:0001514]	formation of translation preinitiation complex [GO:0001731]; positive regulation of translational fidelity [GO:0045903]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]; translation initiation factor activity [GO:0003743]
d4acac2_d3d5de1__1			Euryarchaeota		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; selenocysteine incorporation [GO:0001514]		selenocysteine incorporation [GO:0001514]		cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	
d4acad4_d1a2ke___1		Metazoa	Euryarchaeota	Chordata	cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]; selenocysteine incorporation [GO:0001514]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]; identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]; mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	selenocysteine incorporation [GO:0001514]	mRNA transport [GO:0051028]; negative regulation of vascular endothelial growth factor production [GO:1904046]; nucleocytoplasmic transport [GO:0006913]; positive regulation of protein import into nucleus [GO:0042307]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nuclear pore [GO:0090204]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nuclear inner membrane [GO:0005637]; nuclear membrane [GO:0031965]; nuclear outer membrane [GO:0005640]; nuclear pore central transport channel [GO:0044613]; nucleoplasm [GO:0005654]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	identical protein binding [GO:0042802]; nuclear import signal receptor activity [GO:0061608]; Ran GTPase binding [GO:0008536]; structural constituent of nuclear pore [GO:0017056]
d4acca__d4ic7d___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; beta-catenin destruction complex [GO:0030877]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Wnt signalosome [GO:1990909]; ATP binding [GO:0005524]; beta-catenin binding [GO:0008013]; dynactin binding [GO:0034452]; kinase activity [GO:0016301]; NF-kappaB binding [GO:0051059]; p53 binding [GO:0002039]; protease binding [GO:0002020]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II transcription factor binding [GO:0001085]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; ubiquitin protein ligase binding [GO:0031625]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular response to amyloid-beta [GO:1904646]; cellular response to interleukin-3 [GO:0036016]; circadian rhythm [GO:0007623]; dopamine receptor signaling pathway [GO:0007212]; epithelial to mesenchymal transition [GO:0001837]; ER overload response [GO:0006983]; establishment of cell polarity [GO:0030010]; excitatory postsynaptic potential [GO:0060079]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glycogen metabolic process [GO:0005977]; hippocampus development [GO:0021766]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of dendrite development [GO:2000171]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of neuron death [GO:1901215]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of type B pancreatic cell development [GO:2000077]; neuron projection development [GO:0031175]; neuron projection organization [GO:0106027]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of autophagy [GO:0010508]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of neuron death [GO:1901216]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein localization to centrosome [GO:1904781]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon extension [GO:0030516]; regulation of axonogenesis [GO:0050770]; regulation of cellular response to heat [GO:1900034]; regulation of circadian rhythm [GO:0042752]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of microtubule anchoring at centrosome [GO:0150101]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of microtubule-based process [GO:0032886]; regulation of synaptic vesicle exocytosis [GO:2000300]; signal transduction [GO:0007165]; superior temporal gyrus development [GO:0071109]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; ATP binding [GO:0005524]; MAP kinase activity [GO:0004707]; mitogen-activated protein kinase binding [GO:0051019]; axon guidance [GO:0007411]; cAMP-mediated signaling [GO:0019933]; cell cycle [GO:0007049]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to transforming growth factor beta stimulus [GO:0071560]; intracellular signal transduction [GO:0035556]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of inflammatory response [GO:0050728]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of response to cytokine stimulus [GO:0060761]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of angiogenesis [GO:0045765]; regulation of gene expression [GO:0010468]; signal transduction [GO:0007165]	beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; cellular response to amyloid-beta [GO:1904646]; cellular response to interleukin-3 [GO:0036016]; circadian rhythm [GO:0007623]; dopamine receptor signaling pathway [GO:0007212]; epithelial to mesenchymal transition [GO:0001837]; ER overload response [GO:0006983]; establishment of cell polarity [GO:0030010]; excitatory postsynaptic potential [GO:0060079]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glycogen metabolic process [GO:0005977]; hippocampus development [GO:0021766]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; maintenance of cell polarity [GO:0030011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of dendrite development [GO:2000171]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of neuron death [GO:1901215]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of type B pancreatic cell development [GO:2000077]; neuron projection development [GO:0031175]; neuron projection organization [GO:0106027]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of autophagy [GO:0010508]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of mitochondrion organization [GO:0010822]; positive regulation of neuron death [GO:1901216]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein localization to centrosome [GO:1904781]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon extension [GO:0030516]; regulation of axonogenesis [GO:0050770]; regulation of cellular response to heat [GO:1900034]; regulation of circadian rhythm [GO:0042752]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of microtubule anchoring at centrosome [GO:0150101]; regulation of microtubule-based process [GO:0032886]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of synaptic vesicle exocytosis [GO:2000300]; signal transduction [GO:0007165]; superior temporal gyrus development [GO:0071109]; Wnt signaling pathway [GO:0016055]	axon guidance [GO:0007411]; cAMP-mediated signaling [GO:0019933]; cell cycle [GO:0007049]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to transforming growth factor beta stimulus [GO:0071560]; intracellular signal transduction [GO:0035556]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of inflammatory response [GO:0050728]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of response to cytokine stimulus [GO:0060761]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of angiogenesis [GO:0045765]; regulation of gene expression [GO:0010468]; signal transduction [GO:0007165]	axon [GO:0030424]; beta-catenin destruction complex [GO:0030877]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; Wnt signalosome [GO:1990909]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]	ATP binding [GO:0005524]; beta-catenin binding [GO:0008013]; dynactin binding [GO:0034452]; kinase activity [GO:0016301]; NF-kappaB binding [GO:0051059]; p53 binding [GO:0002039]; protease binding [GO:0002020]; protein kinase A catalytic subunit binding [GO:0034236]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II transcription factor binding [GO:0001085]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; MAP kinase activity [GO:0004707]; mitogen-activated protein kinase binding [GO:0051019]
d4acfa2_d4z9me2__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; phosphocreatine biosynthetic process [GO:0046314]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; phosphocreatine biosynthetic process [GO:0046314]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d4acfb2_d1f52c2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d4acfc1_d1f1hi1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d4acfc1_d4lnoe1__1			Actinobacteria	Firmicutes	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]; cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cellular response to nitrogen levels [GO:0043562]; glutamine biosynthetic process [GO:0006542]; negative regulation of core promoter binding [GO:1904797]; negative regulation of transcription, DNA-templated [GO:0045892]; nitrogen catabolite repression of transcription [GO:0090295]; polyamine catabolic process [GO:0006598]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; glutamine binding [GO:0070406]; metal ion binding [GO:0046872]; transcription factor binding [GO:0008134]
d4acfe1_d3qajl1__1			Actinobacteria		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]		cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	
d4acff1_d1f1hk1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	cytoplasm [GO:0005737]; membrane [GO:0016020]; ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; membrane [GO:0016020]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]
d4acff2_d1qk1b2__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]; evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	evasion or tolerance of host immune response [GO:0020012]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]; pathogenesis [GO:0009405]; positive regulation of plasminogen activation [GO:0010756]	creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; membrane [GO:0016020]; plasma membrane [GO:0005886]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; fibronectin binding [GO:0001968]; glutamate-ammonia ligase activity [GO:0004356]; metal ion binding [GO:0046872]; zymogen binding [GO:0035375]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d4acpa2_d1hxmg2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]; transmembrane signaling receptor activity [GO:0004888]; adaptive immune response [GO:0002250]; immune response [GO:0006955]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adaptive immune response [GO:0002250]; immune response [GO:0006955]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of plasma membrane [GO:0005887]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	transmembrane signaling receptor activity [GO:0004888]
d4acpb1_d3bzeb2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4acpb2_d4y5xk1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]; erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]; brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	brain development [GO:0007420]; decidualization [GO:0046697]; heart development [GO:0007507]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	extracellular region [GO:0005576]; integral component of plasma membrane [GO:0005887]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	erythropoietin receptor activity [GO:0004900]; identical protein binding [GO:0042802]
d4acsa1_d1yzxb___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; protein targeting to peroxisome [GO:0006625]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intracellular [GO:0005622]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	glutathione transferase activity [GO:0004364]	glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein disulfide oxidoreductase activity [GO:0015035]
d4adbb__d3fq8b___1			Proteobacteria	Cyanobacteria	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]	chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]		cytoplasm [GO:0005737]	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d4adca__d2yobb___1		Metazoa	Proteobacteria	Chordata	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]; cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]	cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]		cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]	alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]
d4adcd__d4o6zd1__1			Proteobacteria	Apicomplexa	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]	apicoplast [GO:0020011]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]; cellular response to tetrahydrofolate [GO:1904482]; D-serine metabolic process [GO:0070178]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]	cellular response to tetrahydrofolate [GO:1904482]; D-serine metabolic process [GO:0070178]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]		apicoplast [GO:0020011]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]	amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]
d4addb__d5ax8b___1		Metazoa	Proteobacteria	Chordata	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T-tubule [GO:0030315]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; RNA binding [GO:0003723]; 2-oxoglutarate metabolic process [GO:0006103]; 4-hydroxyproline catabolic process [GO:0019470]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glyoxylate metabolic process [GO:0046487]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]	2-oxoglutarate metabolic process [GO:0006103]; 4-hydroxyproline catabolic process [GO:0019470]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid biosynthetic process [GO:0008652]; fatty acid transport [GO:0015908]; female pregnancy [GO:0007565]; gluconeogenesis [GO:0006094]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glyoxylate metabolic process [GO:0046487]; lactation [GO:0007595]; oxaloacetate metabolic process [GO:0006107]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to muscle activity [GO:0014850]		cell surface [GO:0009986]; extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; T-tubule [GO:0030315]	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; phospholipid binding [GO:0005543]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; RNA binding [GO:0003723]
d4addd__d1i41l___1		Viridiplantae	Proteobacteria	Streptophyta	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]	transsulfuration [GO:0019346]			N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d4adea__d1i48b___1		Viridiplantae	Proteobacteria	Streptophyta	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]; arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]; transsulfuration [GO:0019346]	arginine biosynthetic process via ornithine [GO:0042450]; arginine catabolic process [GO:0006527]; arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]; ornithine catabolic process [GO:0006593]	transsulfuration [GO:0019346]			N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity [GO:0003992]; pyridoxal phosphate binding [GO:0030170]; succinylornithine transaminase activity [GO:0043825]	catalytic activity [GO:0003824]; pyridoxal phosphate binding [GO:0030170]
d4adlb__d1gk3a___1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; histidine ammonia-lyase activity [GO:0004397]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]	fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; tricarboxylic acid cycle enzyme complex [GO:0045239]	cytoplasm [GO:0005737]	fumarate hydratase activity [GO:0004333]	histidine ammonia-lyase activity [GO:0004397]
d4aehl2_d5th9n___1		Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]; cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]		cellular response to cadmium ion [GO:0071276]; cellular response to reactive oxygen species [GO:0034614]; collagen catabolic process [GO:0030574]; cytokine-mediated signaling pathway [GO:0019221]; embryo implantation [GO:0007566]; endodermal cell differentiation [GO:0035987]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; macrophage differentiation [GO:0030225]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cation channel activity [GO:2001258]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of epithelial cell differentiation involved in kidney development [GO:2000697]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; neutrophil degranulation [GO:0043312]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA binding [GO:0043388]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor binding [GO:1900122]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vascular smooth muscle cell proliferation [GO:1904707]; proteolysis [GO:0006508]; regulation of neuroinflammatory response [GO:0150077]; response to amyloid-beta [GO:1904645]; skeletal system development [GO:0001501]		collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; tertiary granule lumen [GO:1904724]		collagen binding [GO:0005518]; endopeptidase activity [GO:0004175]; identical protein binding [GO:0042802]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; serine-type endopeptidase activity [GO:0004252]; zinc ion binding [GO:0008270]
d4aeim2_d3c5zc1__1	Metazoa	Metazoa	Arthropoda	Chordata	extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	defense response [GO:0006952]	antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; B cell affinity maturation [GO:0002344]; cellular response to interferon-gamma [GO:0071346]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of alpha-beta T cell activation [GO:0046635]; positive regulation of antigen processing and presentation [GO:0002579]; positive regulation of T-helper 1 type immune response [GO:0002827]	extracellular region [GO:0005576]	cell surface [GO:0009986]; early endosome [GO:0005769]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; MHC class II protein complex [GO:0042613]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]	sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]	peptide antigen binding [GO:0042605]; protein antigen binding [GO:1990405]; protein heterodimerization activity [GO:0046982]; toxic substance binding [GO:0015643]; transcription factor binding [GO:0008134]; ubiquitin protein ligase binding [GO:0031625]
d4aein1_d1u8ja1__1	Metazoa		Arthropoda		extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]		defense response [GO:0006952]		extracellular region [GO:0005576]		sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]	
d4aein2_d1rhhc2__1	Metazoa		Arthropoda		extracellular region [GO:0005576]; sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]; defense response [GO:0006952]		defense response [GO:0006952]		extracellular region [GO:0005576]		sodium channel inhibitor activity [GO:0019871]; toxin activity [GO:0090729]	
d4af2a1_d1gsca2__1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]; glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	glutathione metabolic process [GO:0006749]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; sensory perception of smell [GO:0007608]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	cytosol [GO:0005829]; extracellular region [GO:0005576]; protein-containing complex [GO:0032991]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]	glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; nickel cation binding [GO:0016151]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; steroid binding [GO:0005496]
d4af2a1_d4xtsf___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]; hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell [GO:0005623]; cytosol [GO:0005829]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]	cell redox homeostasis [GO:0045454]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; periplasmic space [GO:0042597]	cell [GO:0005623]; cytosol [GO:0005829]	hydroperoxide reductase activity [GO:0032843]; thioredoxin peroxidase activity [GO:0008379]	thioredoxin peroxidase activity [GO:0008379]
d4af6b2_d3vo2a2__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	chloroplast [GO:0009507]; ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	photosynthesis [GO:0015979]		chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	chloroplast [GO:0009507]	ferredoxin-NADP+ reductase activity [GO:0004324]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d4af7a1_d2x3ua1__1	Viridiplantae		Streptophyta	Cyanobacteria	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	photosynthesis [GO:0015979]	oxidation-reduction process [GO:0055114]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	phycobilisome [GO:0030089]	ferredoxin-NADP+ reductase activity [GO:0004324]	ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]
d4af7a2_d3ozva3__1	Viridiplantae		Streptophyta	Proteobacteria	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; ferredoxin-NADP+ reductase activity [GO:0004324]; photosynthesis [GO:0015979]	cytoplasm [GO:0005737]; FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]; response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	photosynthesis [GO:0015979]	response to nitrosative stress [GO:0051409]; response to toxic substance [GO:0009636]	chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]	cytoplasm [GO:0005737]	ferredoxin-NADP+ reductase activity [GO:0004324]	FAD binding [GO:0071949]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric oxide dioxygenase activity [GO:0008941]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344]
d4afgb__d2w8fe___1	Metazoa	Metazoa	Annelida	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d4afnc1_d3vdqa___1			Proteobacteria	Proteobacteria	3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]	fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]				3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [GO:0004316]; 3-oxo-glutaryl-[acp] methyl ester reductase activity [GO:0102131]; 3-oxo-pimeloyl-[acp] methyl ester reductase activity [GO:0102132]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	3-hydroxybutyrate dehydrogenase activity [GO:0003858]; nucleotide binding [GO:0000166]
d4afoa__d1uv6a___1		Metazoa		Mollusca		cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]				cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]		extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d4ag7a__d4koxa___1	Metazoa		Nematoda (roundworms)	Proteobacteria	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]		glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]
d4ag7b__d5hmnb1__1	Metazoa		Nematoda (roundworms)		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	N-acetyltransferase activity [GO:0008080]	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]		glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]	N-acetyltransferase activity [GO:0008080]
d4ag9a__d4zgyb___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]; glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; ornithine decarboxylase inhibitor activity [GO:0008073]; negative regulation of polyamine transmembrane transport [GO:1902268]; polyamine biosynthetic process [GO:0006596]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of protein catabolic process [GO:0045732]; regulation of cellular amino acid metabolic process [GO:0006521]	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	negative regulation of polyamine transmembrane transport [GO:1902268]; polyamine biosynthetic process [GO:0006596]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of protein catabolic process [GO:0045732]; regulation of cellular amino acid metabolic process [GO:0006521]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; Golgi apparatus [GO:0005794]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; monosaccharide binding [GO:0048029]	ornithine decarboxylase inhibitor activity [GO:0008073]
d4agja__d3s9ba___1		Metazoa		Chordata	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	extracellular region [GO:0005576]; serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]		host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]	extracellular region [GO:0005576]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	serine-type endopeptidase activity [GO:0004252]; toxin activity [GO:0090729]
d4agja__d3suga1__1					host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]; RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; suppression by virus of host innate immune response [GO:0039503]; transformation of host cell by virus [GO:0019087]; viral entry into host cell [GO:0046718]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasm [GO:0030430]; host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; T=4 icosahedral viral capsid [GO:0039619]; virion membrane [GO:0055036]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	RNA binding [GO:0003723]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d4agla__d2v2tb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	antigen processing and presentation [GO:0019882]; cellular response to osmotic stress [GO:0071470]; circadian regulation of gene expression [GO:0032922]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; lymphocyte differentiation [GO:0030098]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; response to cytokine [GO:0034097]; T-helper 1 cell differentiation [GO:0045063]; T-helper 1 type immune response [GO:0042088]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	centrosome [GO:0005813]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; transcriptional repressor complex [GO:0017053]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]
d4agoa__d4ibtd___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d4agob__d1imhc2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cytokine production [GO:0001816]; excretion [GO:0007588]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; response to osmotic stress [GO:0006970]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	calcineurin-NFAT signaling cascade [GO:0033173]; cellular response to cytokine stimulus [GO:0071345]; cytokine production [GO:0001816]; excretion [GO:0007588]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; response to osmotic stress [GO:0006970]; signal transduction [GO:0007165]; transcription by RNA polymerase II [GO:0006366]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d4agpb__d1pzuh2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]; B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; calcineurin-NFAT signaling cascade [GO:0033173]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cytokine production [GO:0001816]; Fc-epsilon receptor signaling pathway [GO:0038095]; myotube cell development [GO:0014904]; negative regulation of vascular smooth muscle cell differentiation [GO:1905064]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nuclear transcription factor complex [GO:0044798]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; transcription factor complex [GO:0005667]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; phosphatase binding [GO:0019902]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription factor binding [GO:0008134]
d4ah2a2_d4d9ll2__1	Metazoa		Chordata		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]; MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; detection of bacterium [GO:0016045]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immune response [GO:0006955]; immunoglobulin production involved in immunoglobulin mediated immune response [GO:0002381]; inflammatory response to antigenic stimulus [GO:0002437]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein tetramerization [GO:0051262]; regulation of interleukin-10 secretion [GO:2001179]; regulation of interleukin-4 production [GO:0032673]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]		clathrin-coated endocytic vesicle membrane [GO:0030669]; endocytic vesicle membrane [GO:0030666]; ER to Golgi transport vesicle membrane [GO:0012507]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; integral component of lumenal side of endoplasmic reticulum membrane [GO:0071556]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588]; transport vesicle membrane [GO:0030658]		MHC class II protein complex binding [GO:0023026]; peptide antigen binding [GO:0042605]; virus receptor activity [GO:0001618]	
d4ahha__d1bela___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	extracellular region [GO:0005576]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d4ahka__d1kf5a___1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]; actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]; actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	actin filament polymerization [GO:0030041]; activation of phospholipase A2 activity [GO:0032431]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiogenesis [GO:0001525]; antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cell communication [GO:0007154]; cell migration [GO:0016477]; defense response to Gram-positive bacterium [GO:0050830]; diacylglycerol biosynthetic process [GO:0006651]; homeostatic process [GO:0042592]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; placenta development [GO:0001890]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein secretion [GO:0050714]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to yeast [GO:0001878]; rRNA transcription [GO:0009303]		actin cytoskeleton [GO:0015629]; angiogenin-PRI complex [GO:0032311]; basement membrane [GO:0005604]; cytoplasmic vesicle [GO:0031410]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleus [GO:0005634]	extracellular region [GO:0005576]	actin binding [GO:0003779]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; heparin binding [GO:0008201]; peptide binding [GO:0042277]; protein homodimerization activity [GO:0042803]; ribonuclease activity [GO:0004540]; rRNA binding [GO:0019843]; signaling receptor binding [GO:0005102]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d4ahqd__d1ub3b___1			Firmicutes	Deinococcus-Thermus	cytosol [GO:0005829]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	N-acetylneuraminate lyase activity [GO:0008747]	deoxyribose-phosphate aldolase activity [GO:0004139]
d4ahxa1_d3teya2__1	Fungi		Ascomycota	Firmicutes	anchored component of membrane [GO:0031225]; cell periphery [GO:0071944]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]; mannose binding [GO:0005537]; cell-substrate adhesion [GO:0031589]; coflocculation [GO:0036281]; flocculation [GO:0000128]; flocculation via cell wall protein-carbohydrate interaction [GO:0000501]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]; negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process in other organism [GO:0044533]; protein homooligomerization [GO:0051260]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	cell-substrate adhesion [GO:0031589]; coflocculation [GO:0036281]; flocculation [GO:0000128]; flocculation via cell wall protein-carbohydrate interaction [GO:0000501]	negative regulation of gene expression [GO:0010629]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process in other organism [GO:0044533]; protein homooligomerization [GO:0051260]; proteolysis in other organism [GO:0035897]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of proteasomal protein catabolic process [GO:0061136]	anchored component of membrane [GO:0031225]; cell periphery [GO:0071944]; extracellular region [GO:0005576]; fungal-type cell wall [GO:0009277]	extracellular region [GO:0005576]	mannose binding [GO:0005537]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; toxin activity [GO:0090729]
d4ai5e1_d4aiab___1												
d4ai9a__d3bkza___1	Metazoa		Chordata	Proteobacteria	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; oxidative demethylation [GO:0070989]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]; RNA repair [GO:0042245]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]		histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	1-ethyladenine demethylase activity [GO:0103053]; dioxygenase activity [GO:0051213]; DNA-N1-methyladenine dioxygenase activity [GO:0043734]; ferrous iron binding [GO:0008198]; oxidative RNA demethylase activity [GO:0035515]
d4ai9a__d5f5aa___1	Metazoa	Metazoa	Chordata	Chordata	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d4ai9b__d5pjaa___1	Metazoa	Metazoa	Chordata	Chordata	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d4aiaa1_d1mpga1__1				Proteobacteria		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d4aiac__d3cvsd1__1				Proteobacteria		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to DNA damage stimulus [GO:0006974]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]		alkylated DNA binding [GO:0032131]; alkylbase DNA N-glycosylase activity [GO:0003905]; DNA-3-methyladenine glycosylase activity [GO:0008725]; DNA-3-methylguanine glycosylase activity [GO:0052822]; DNA-7-methyladenine glycosylase activity [GO:0052821]; DNA-7-methylguanine glycosylase activity [GO:0043916]
d4aiea1_d2vzoa3__1			Firmicutes	Actinobacteria	glucan 1,6-alpha-glucosidase activity [GO:0043896]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]	glucan 1,6-alpha-glucosidase activity [GO:0043896]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; exo-1,4-beta-D-glucosaminidase activity [GO:0052761]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d4aiea2_d3hg3b2__1		Metazoa	Firmicutes	Chordata	glucan 1,6-alpha-glucosidase activity [GO:0043896]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]; glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]	carbohydrate metabolic process [GO:0005975]	glycoside catabolic process [GO:0016139]; glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; neutrophil degranulation [GO:0043312]; oligosaccharide metabolic process [GO:0009311]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]	glucan 1,6-alpha-glucosidase activity [GO:0043896]; metal ion binding [GO:0046872]	alpha-galactosidase activity [GO:0004557]; catalytic activity [GO:0003824]; galactoside binding [GO:0016936]; hydrolase activity [GO:0016787]; protein homodimerization activity [GO:0042803]; raffinose alpha-galactosidase activity [GO:0052692]; signaling receptor binding [GO:0005102]
d4aiga__d1atla___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]; collagen catabolic process [GO:0030574]		collagen catabolic process [GO:0030574]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; toxin activity [GO:0090729]
d4aiua2_d4im4c___1			Bacteroidetes	Firmicutes	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	extracellular region [GO:0005576]; acetylxylan esterase activity [GO:0046555]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]; glucomannan catabolic process [GO:2000884]; xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	cellulose catabolic process [GO:0030245]; glucomannan catabolic process [GO:2000884]; xylan catabolic process [GO:0045493]		extracellular region [GO:0005576]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]	acetylxylan esterase activity [GO:0046555]; cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d4aiva__d1z02f1__1			Actinobacteria	Proteobacteria	nitrite reductase complex [NAD(P)H] [GO:0009344]; 2 iron, 2 sulfur cluster binding [GO:0051537]; nitrite efflux transmembrane transporter activity [GO:0015514]; nitrite reductase [NAD(P)H] activity [GO:0008942]; anaerobic respiration [GO:0009061]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]	anaerobic respiration [GO:0009061]		nitrite reductase complex [NAD(P)H] [GO:0009344]		2 iron, 2 sulfur cluster binding [GO:0051537]; nitrite efflux transmembrane transporter activity [GO:0015514]; nitrite reductase [NAD(P)H] activity [GO:0008942]	2 iron, 2 sulfur cluster binding [GO:0051537]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d4aixa__d4p46b2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4aixb__d1uweh1__1												
d4aixc__d1igjd1__1												
d4aixc__d4cnib1__1		Metazoa		Chordata		cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]		cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]		cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]
d4aizb__d3rvwc2__1	Metazoa	Metazoa	Chordata	Arthropoda	extracellular region [GO:0005576]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	extracellular region [GO:0005576]; cysteine-type peptidase activity [GO:0008234]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]	extracellular region [GO:0005576]		cysteine-type peptidase activity [GO:0008234]
d4aizb__d5dfwh1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	basolateral plasma membrane [GO:0016323]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tetraspanin-enriched microdomain [GO:0097197]; vesicle [GO:0031982]; cholesterol binding [GO:0015485]; integrin binding [GO:0005178]; MHC class II protein binding [GO:0042289]; MHC class II protein complex binding [GO:0023026]; transferrin receptor binding [GO:1990459]; virus receptor activity [GO:0001618]; activation of MAPK activity [GO:0000187]; CD4-positive, alpha-beta T cell costimulation [GO:0035783]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunological synapse formation [GO:0001771]; macrophage fusion [GO:0034238]; myoblast fusion involved in skeletal muscle regeneration [GO:0014905]; osteoclast fusion [GO:0072675]; positive regulation of 1-phosphatidylinositol 4-kinase activity [GO:0043128]; positive regulation of adaptive immune memory response [GO:1905676]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein catabolic process in the vacuole [GO:1904352]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of receptor clustering [GO:1903911]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization [GO:0008104]; protein localization to lysosome [GO:0061462]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of macrophage migration [GO:1905521]; regulation of protein stability [GO:0031647]; viral entry into host cell [GO:0046718]	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]	activation of MAPK activity [GO:0000187]; CD4-positive, alpha-beta T cell costimulation [GO:0035783]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunological synapse formation [GO:0001771]; macrophage fusion [GO:0034238]; myoblast fusion involved in skeletal muscle regeneration [GO:0014905]; osteoclast fusion [GO:0072675]; positive regulation of 1-phosphatidylinositol 4-kinase activity [GO:0043128]; positive regulation of adaptive immune memory response [GO:1905676]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000563]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of inflammatory response to antigenic stimulus [GO:0002863]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein catabolic process in the vacuole [GO:1904352]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of receptor clustering [GO:1903911]; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001190]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization [GO:0008104]; protein localization to lysosome [GO:0061462]; protein localization to plasma membrane [GO:0072659]; receptor internalization [GO:0031623]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; regulation of macrophage migration [GO:1905521]; regulation of protein stability [GO:0031647]; viral entry into host cell [GO:0046718]	extracellular region [GO:0005576]	basolateral plasma membrane [GO:0016323]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tetraspanin-enriched microdomain [GO:0097197]; vesicle [GO:0031982]		cholesterol binding [GO:0015485]; integrin binding [GO:0005178]; MHC class II protein binding [GO:0042289]; MHC class II protein complex binding [GO:0023026]; transferrin receptor binding [GO:1990459]; virus receptor activity [GO:0001618]
d4aizd__d5k8am2__1	Metazoa		Chordata		extracellular region [GO:0005576]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; leukocyte migration [GO:0050900]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]		extracellular region [GO:0005576]			
d4aj0a__d2edfa1__1		Metazoa		Chordata		cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]; ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]		G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]		cytosol [GO:0005829]; M band [GO:0031430]; myofibril [GO:0030016]; nuclear body [GO:0016604]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; Z disc [GO:0030018]		ankyrin binding [GO:0030506]; ATP binding [GO:0005524]; calmodulin binding [GO:0005516]; metal ion binding [GO:0046872]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein serine/threonine kinase activity [GO:0004674]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; structural constituent of muscle [GO:0008307]; titin binding [GO:0031432]
d4aj0c__d5lcvl2__1						extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; 4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d4aj0d__d2ck0l1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4aj0d__d5u72d1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4aj1c2_d2aa3b2__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]; nucleotide binding [GO:0000166]
d4aj1d2_d3h3ja2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]
d4aj2b2_d2v6md2__1	Metazoa		Chordata	Deinococcus-Thermus	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]
d4aj4c1_d1ldea2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d4aj4c2_d1smkh2__1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	glyoxysome [GO:0009514]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-malate dehydrogenase activity [GO:0030060]
d4aj4d2_d2ydnc2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	
d4aj7a__d2eiod___1	Metazoa		Arthropoda	Proteobacteria	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d4aj7a__d3fr3b1__1	Metazoa		Arthropoda	Apicomplexa	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	glutathione transferase activity [GO:0004364]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]		cell [GO:0005623]		protein disulfide oxidoreductase activity [GO:0015035]	glutathione transferase activity [GO:0004364]
d4aj7b__d1f6md___1	Metazoa		Arthropoda	Proteobacteria	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]	protein disulfide oxidoreductase activity [GO:0015035]	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d4aj7b__d3kh7a1__1	Metazoa		Arthropoda	Proteobacteria	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; integral component of membrane [GO:0016021]; outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]; disulfide oxidoreductase activity [GO:0015036]; cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	cell [GO:0005623]	cell [GO:0005623]; integral component of membrane [GO:0016021]; outer membrane-bounded periplasmic space [GO:0030288]; plasma membrane [GO:0005886]	protein disulfide oxidoreductase activity [GO:0015035]	disulfide oxidoreductase activity [GO:0015036]
d4aj8a__d1zyek1__1	Metazoa	Metazoa	Arthropoda	Chordata	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; maternal placenta development [GO:0001893]; mitochondrion organization [GO:0007005]; myeloid cell differentiation [GO:0030099]; negative regulation of kinase activity [GO:0033673]; peptidyl-cysteine oxidation [GO:0018171]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; regulation of mitochondrial membrane potential [GO:0051881]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; protein-containing complex [GO:0032991]	protein disulfide oxidoreductase activity [GO:0015035]	cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; thioredoxin peroxidase activity [GO:0008379]
d4ajda1_d3hqya___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]
d4ajdd1_d1y2ka___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d4ajeb1_d2hk8b2__1	Metazoa		Chordata	Aquificae	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	NADP binding [GO:0050661]; shikimate 3-dehydrogenase (NADP+) activity [GO:0004764]
d4ajed1_d1kevd2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	isopropanol dehydrogenase (NADP+) activity [GO:0050009]; zinc ion binding [GO:0008270]
d4ajed2_d2xxed2__1	Metazoa		Chordata		cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	
d4ajgd1_d1rkob___1	Metazoa		Chordata		cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]		cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]		cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]		3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	
d4ajhd1_d2fzeb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	ethanol oxidation [GO:0006069]; fatty acid omega-oxidation [GO:0010430]; formaldehyde catabolic process [GO:0046294]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of blood pressure [GO:0045777]; respiratory system process [GO:0003016]; response to lipopolysaccharide [GO:0032496]; response to nitrosative stress [GO:0051409]; response to redox state [GO:0051775]; retinoid metabolic process [GO:0001523]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; electron transfer activity [GO:0009055]; fatty acid binding [GO:0005504]; formaldehyde dehydrogenase activity [GO:0018467]; protein homodimerization activity [GO:0042803]; S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903]; zinc ion binding [GO:0008270]
d4ajib1_d1enpa___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	chloroplast [GO:0009507]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid biosynthetic process [GO:0006633]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]	chloroplast [GO:0009507]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]
d4ajib2_d3fi9a2__1	Metazoa		Chordata	Bacteroidetes	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	malate dehydrogenase activity [GO:0016615]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	malate dehydrogenase activity [GO:0016615]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d4ajic1_d1gtmb1__1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d4ajid1_d1gu7a2__1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	mitochondrion [GO:0005739]; trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]	mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	trans-2-enoyl-CoA reductase (NADPH) activity [GO:0019166]
d4ajid1_d5je8c1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	3-hydroxyisobutyrate dehydrogenase activity [GO:0008442]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d4ajjb1_d3dhea___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]; estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]
d4ajjd1_d1hszb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d4ajjd1_d4pzdh1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]; fatty acid metabolic process [GO:0006631]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	fatty acid metabolic process [GO:0006631]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; NAD+ binding [GO:0070403]
d4ajkb2_d3pqdb2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]
d4ajkb2_d4wloa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d4ajkc2_d1uxia2__1	Metazoa		Chordata	Chloroflexi	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-malate dehydrogenase activity [GO:0030060]
d4ajkc2_d3d0ob2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]
d4ajkd1_d2ldxc1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]; L-lactate dehydrogenase activity [GO:0004459]; ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	ATP biosynthetic process [GO:0006754]; carbohydrate metabolic process [GO:0005975]; flagellated sperm motility [GO:0030317]; lactate biosynthetic process from pyruvate [GO:0019244]; lactate oxidation [GO:0019516]; pyruvate metabolic process [GO:0006090]	cytoplasm [GO:0005737]	cilium [GO:0005929]; cytoplasm [GO:0005737]; motile cilium [GO:0031514]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]
d4ajkd2_d4rlsa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d4ajlc2_d1emda2__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]; anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	anaerobic respiration [GO:0009061]; fermentation [GO:0006113]; glycolytic process [GO:0006096]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; membrane [GO:0016020]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase activity [GO:0016615]; oxidoreductase activity [GO:0016491]
d4ajmd__d3sl4c___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d4ajna2_d3pqea2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]
d4ajnd1_d5itvb1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	oxidoreductase activity [GO:0016491]; antibiotic biosynthetic process [GO:0017000]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	antibiotic biosynthetic process [GO:0017000]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	oxidoreductase activity [GO:0016491]
d4ajod2_d4b7ud2__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]
d4ajpc2_d4uula2__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]; nucleotide binding [GO:0000166]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]		cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]; L-malate dehydrogenase activity [GO:0030060]; nucleotide binding [GO:0000166]
d4ajpd1_d4cl3a1__1	Metazoa		Chordata	Chloroflexi	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-malate dehydrogenase activity [GO:0030060]
d4ajra__d1tyoa___1			Proteobacteria	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]
d4ajsa__d5yfna1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]; 2-oxoglutarate metabolic process [GO:0006103]; female gonad development [GO:0008585]; glutathione metabolic process [GO:0006749]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; NADPH regeneration [GO:0006740]; neutrophil degranulation [GO:0043312]; protein targeting to peroxisome [GO:0006625]; regulation of phospholipid biosynthetic process [GO:0071071]; regulation of phospholipid catabolic process [GO:0060696]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; tricarboxylic acid cycle [GO:0006099]	electron transport chain [GO:0022900]; glyoxylate cycle [GO:0006097]; response to oxidative stress [GO:0006979]; tricarboxylic acid cycle [GO:0006099]	2-oxoglutarate metabolic process [GO:0006103]; female gonad development [GO:0008585]; glutathione metabolic process [GO:0006749]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADPH regeneration [GO:0006740]; NADP metabolic process [GO:0006739]; neutrophil degranulation [GO:0043312]; protein targeting to peroxisome [GO:0006625]; regulation of phospholipid biosynthetic process [GO:0071071]; regulation of phospholipid catabolic process [GO:0060696]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; mitochondrion [GO:0005739]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; secretory granule lumen [GO:0034774]; tertiary granule lumen [GO:1904724]	isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; isocitrate dehydrogenase (NADP+) activity [GO:0004450]; magnesium ion binding [GO:0000287]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; protein homodimerization activity [GO:0042803]
d4ak8c__d1afa31__1	Metazoa	Metazoa	Chordata	Chordata	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; defense response to virus [GO:0051607]; receptor-mediated endocytosis [GO:0006898]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	clathrin-coated endocytic vesicle membrane [GO:0030669]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; mannose binding [GO:0005537]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d4akda1_d4ddnd___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]					carbohydrate binding [GO:0030246]	carbohydrate binding [GO:0030246]
d4akma__d5gv0a1__1	Metazoa	Metazoa	Chordata	Chordata	alveolar lamellar body membrane [GO:0097233]; early endosome [GO:0005769]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; adaptive immune response [GO:0002250]; establishment of protein localization to organelle [GO:0072594]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of proteasomal protein catabolic process [GO:1901799]; positive regulation of gene expression [GO:0010628]; regulation of autophagy [GO:0010506]; regulation of viral life cycle [GO:1903900]; response to interferon-alpha [GO:0035455]	alveolar lamellar body [GO:0097208]; autolysosome [GO:0044754]; cell surface [GO:0009986]; cytolytic granule [GO:0044194]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome [GO:0005768]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; integral component of synaptic vesicle membrane [GO:0030285]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; phagolysosome membrane [GO:0061474]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; vacuole [GO:0005773]; vesicle [GO:0031982]; enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]; autophagic cell death [GO:0048102]; establishment of protein localization to organelle [GO:0072594]; Golgi to lysosome transport [GO:0090160]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; protein stabilization [GO:0050821]; regulation of organelle transport along microtubule [GO:1902513]; spermatogenesis [GO:0007283]	adaptive immune response [GO:0002250]; establishment of protein localization to organelle [GO:0072594]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of proteasomal protein catabolic process [GO:1901799]; positive regulation of gene expression [GO:0010628]; regulation of autophagy [GO:0010506]; regulation of viral life cycle [GO:1903900]; response to interferon-alpha [GO:0035455]	autophagic cell death [GO:0048102]; establishment of protein localization to organelle [GO:0072594]; Golgi to lysosome transport [GO:0090160]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; protein stabilization [GO:0050821]; regulation of organelle transport along microtubule [GO:1902513]; spermatogenesis [GO:0007283]	alveolar lamellar body membrane [GO:0097233]; early endosome [GO:0005769]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	alveolar lamellar body [GO:0097208]; autolysosome [GO:0044754]; cell surface [GO:0009986]; cytolytic granule [GO:0044194]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome [GO:0005768]; endosome membrane [GO:0010008]; external side of plasma membrane [GO:0009897]; integral component of synaptic vesicle membrane [GO:0030285]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome [GO:0042470]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; phagolysosome membrane [GO:0061474]; plasma membrane [GO:0005886]; sarcolemma [GO:0042383]; synaptic vesicle [GO:0008021]; vacuole [GO:0005773]; vesicle [GO:0031982]		enzyme binding [GO:0019899]; protein domain specific binding [GO:0019904]
d4akna__d5pd6a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	nucleus [GO:0005634]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d4akoa2_d4knse2__1			Firmicutes	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	sporulation resulting in formation of a cellular spore [GO:0030435]	nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]		copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d4akoa3_d3in0b___1			Firmicutes	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	sporulation resulting in formation of a cellular spore [GO:0030435]	oxidation-reduction process [GO:0055114]	outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d4akpa2_d3eh5b2__1			Firmicutes	Deinococcus-Thermus	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]; copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]	sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; respirasome [GO:0070469]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; cytochrome-c oxidase activity [GO:0004129]
d4akqa3_d1cura___1			Firmicutes	Proteobacteria	outer membrane-bounded periplasmic space [GO:0030288]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; sporulation resulting in formation of a cellular spore [GO:0030435]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	sporulation resulting in formation of a cellular spore [GO:0030435]		outer membrane-bounded periplasmic space [GO:0030288]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d4akza__d1hkxa___1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; pathogenesis [GO:0009405]; protein secretion by the type IV secretion system [GO:0030255]	axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]; ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]; angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron migration [GO:2001222]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]	pathogenesis [GO:0009405]; protein secretion by the type IV secretion system [GO:0030255]	angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neuron migration [GO:2001222]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	axon [GO:0030424]; calcium- and calmodulin-dependent protein kinase complex [GO:0005954]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic spine [GO:0043197]; glutamatergic postsynaptic density [GO:0099573]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; postsynaptic specialization membrane [GO:0099634]; presynaptic cytosol [GO:0099523]; Schaffer collateral - CA1 synapse [GO:0098685]	identical protein binding [GO:0042802]	ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; glutamate receptor binding [GO:0035254]; GTPase activating protein binding [GO:0032794]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; protein serine/threonine kinase activity [GO:0004674]
d4al2b__d4e9aa___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	translation [GO:0006412]	cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d4al2c__d4dr8d___1			Proteobacteria	Cyanobacteria	cytosol [GO:0005829]; ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]; co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]; translation [GO:0006412]	co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; translation [GO:0006412]	translation [GO:0006412]	cytosol [GO:0005829]		ferrous iron binding [GO:0008198]; hydrolase activity [GO:0016787]; peptide deformylase activity [GO:0042586]; ribosome binding [GO:0043022]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; peptide deformylase activity [GO:0042586]
d4al4a1_d1gegf___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]; acetoin catabolic process [GO:0045150]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	acetoin catabolic process [GO:0045150]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	diacetyl reductase ((S)-acetoin forming) activity [GO:0052588]
d4al4b1_d3a9wb___1	Metazoa		Chordata	Euryarchaeota	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	catalytic activity [GO:0003824]; coenzyme binding [GO:0050662]; nucleotide binding [GO:0000166]
d4al4b2_d3pqfd2__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]
d4al4c2_d5k0zd2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytosol [GO:0005829]; L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; pyruvate metabolic process [GO:0006090]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	carbohydrate metabolic process [GO:0005975]; pyruvate metabolic process [GO:0006090]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	L-lactate dehydrogenase activity [GO:0004459]
d4al4d1_d1a4ib1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity [GO:0004486]; 10-formyltetrahydrofolate biosynthetic process [GO:0009257]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; folic acid metabolic process [GO:0046655]; heart development [GO:0007507]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; one-carbon metabolic process [GO:0006730]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; serine family amino acid biosynthetic process [GO:0009070]; serine family amino acid metabolic process [GO:0009069]; somite development [GO:0061053]; tetrahydrofolate interconversion [GO:0035999]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	10-formyltetrahydrofolate biosynthetic process [GO:0009257]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic viscerocranium morphogenesis [GO:0048703]; folic acid metabolic process [GO:0046655]; heart development [GO:0007507]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; one-carbon metabolic process [GO:0006730]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; serine family amino acid biosynthetic process [GO:0009070]; serine family amino acid metabolic process [GO:0009069]; somite development [GO:0061053]; tetrahydrofolate interconversion [GO:0035999]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	ATP binding [GO:0005524]; formate-tetrahydrofolate ligase activity [GO:0004329]; methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NAD+) activity [GO:0004487]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity [GO:0004486]
d4al4d2_d2hjre2__1	Metazoa		Chordata	Apicomplexa	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytoplasm [GO:0005737]		identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d4al8l1_d1iqda1__1		Metazoa		Chordata	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]; copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]; acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]	cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	COPII-coated ER to Golgi transport vesicle [GO:0030134]; endoplasmic reticulum-Golgi intermediate compartment membrane [GO:0033116]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; platelet alpha granule lumen [GO:0031093]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	copper ion binding [GO:0005507]; oxidoreductase activity [GO:0016491]
d4al8l1_d4rqql1__1					cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral budding from ER membrane [GO:0046762]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		cytoplasmic viral factory [GO:0039714]; extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	
d4al9d__d4qdqb1__1		Metazoa	Proteobacteria	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	axon [GO:0030424]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; integral component of postsynaptic membrane [GO:0099055]; membrane [GO:0016020]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116]; cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; semaphorin receptor activity [GO:0017154]; signaling receptor activity [GO:0038023]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; angiogenesis [GO:0001525]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to leukemia inhibitory factor [GO:1990830]; dorsal root ganglion morphogenesis [GO:1904835]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; negative chemotaxis [GO:0050919]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of postsynapse organization [GO:0099175]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; trigeminal ganglion development [GO:0061551]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]; viral process [GO:0016032]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	angiogenesis [GO:0001525]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to leukemia inhibitory factor [GO:1990830]; dorsal root ganglion morphogenesis [GO:1904835]; facial nerve structural organization [GO:0021612]; facioacoustic ganglion development [GO:1903375]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; negative chemotaxis [GO:0050919]; nerve development [GO:0021675]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of postsynapse organization [GO:0099175]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sensory neuron axon guidance [GO:0097374]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; trigeminal ganglion development [GO:0061551]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; ventral trunk neural crest cell migration [GO:0036486]; vestibulocochlear nerve structural organization [GO:0021649]; viral process [GO:0016032]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	axon [GO:0030424]; extracellular region [GO:0005576]; glutamatergic synapse [GO:0098978]; integral component of membrane [GO:0016021]; integral component of postsynaptic membrane [GO:0099055]; membrane [GO:0016020]; plasma membrane [GO:0005886]; semaphorin receptor complex [GO:0002116]	carbohydrate binding [GO:0030246]	cytokine binding [GO:0019955]; growth factor binding [GO:0019838]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; semaphorin receptor activity [GO:0017154]; signaling receptor activity [GO:0038023]; vascular endothelial growth factor-activated receptor activity [GO:0005021]
d4alal1_d1ic4l___1		Metazoa		Chordata	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	protein dimerization activity [GO:0046983]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]
d4alca__d4jqia1__1		Metazoa	Firmicutes	Chordata	extracellular region [GO:0005576]; chitin binding [GO:0008061]; copper ion binding [GO:0005507]; monooxygenase activity [GO:0004497]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	clathrin-coated vesicle membrane [GO:0030665]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; G protein-coupled receptor activity [GO:0004930]; vasopressin receptor activity [GO:0005000]; activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cellular response to hormone stimulus [GO:0032870]; excretion [GO:0007588]; G protein-coupled receptor signaling pathway [GO:0007186]; hemostasis [GO:0007599]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interferon-gamma production [GO:0032609]; membrane organization [GO:0061024]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of urine volume [GO:0035811]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of vasoconstriction [GO:0045907]; regulation of systemic arterial blood pressure by vasopressin [GO:0001992]; renal water homeostasis [GO:0003091]; response to cytokine [GO:0034097]; telencephalon development [GO:0021537]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cellular response to hormone stimulus [GO:0032870]; excretion [GO:0007588]; G protein-coupled receptor signaling pathway [GO:0007186]; hemostasis [GO:0007599]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interferon-gamma production [GO:0032609]; membrane organization [GO:0061024]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of urine volume [GO:0035811]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of vasoconstriction [GO:0045907]; regulation of systemic arterial blood pressure by vasopressin [GO:0001992]; renal water homeostasis [GO:0003091]; response to cytokine [GO:0034097]; telencephalon development [GO:0021537]	extracellular region [GO:0005576]	clathrin-coated vesicle membrane [GO:0030665]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	chitin binding [GO:0008061]; copper ion binding [GO:0005507]; monooxygenase activity [GO:0004497]	G protein-coupled receptor activity [GO:0004930]; vasopressin receptor activity [GO:0005000]
d4alha__d4c67a1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]
d4alhc__d4nyvd___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d4alsa__d2f08b___1		Metazoa	Firmicutes	Arthropoda	extracellular region [GO:0005576]; chitin binding [GO:0008061]; copper ion binding [GO:0005507]; monooxygenase activity [GO:0004497]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		extracellular region [GO:0005576]	extracellular region [GO:0005576]	chitin binding [GO:0008061]; copper ion binding [GO:0005507]; monooxygenase activity [GO:0004497]	
d4alxd__d2ymef___1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d4alxf__d1i9bc1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d4alxf__d5tvhe1__1	Metazoa	Metazoa	Mollusca	Mollusca	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d4am0b1_d3sdxd___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4am0d1_d5e5ma___1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]; adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune system process [GO:0002376]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of immune response [GO:0050777]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of apoptotic process [GO:0043065]; T cell receptor signaling pathway [GO:0050852]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	clathrin-coated endocytic vesicle [GO:0045334]; external side of plasma membrane [GO:0009897]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; perinuclear region of cytoplasm [GO:0048471]; protein complex involved in cell adhesion [GO:0098636]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	
d4am0d2_d4hh9c1__1					extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	
d4am0f1_d1m7ib2__1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4am0f2_d4l8cg2__1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4am0l2_d4pj5e2__1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4am0t__d2a9ba1__1		Metazoa		Chordata	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]; nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	heme binding [GO:0020037]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; sulfite oxidase activity [GO:0008482]
d4am0t__d2oxhc___1				Proteobacteria	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell mitochondrion [GO:0033650]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]	
d4am1a1_d4z9mf1__1	Metazoa	Metazoa	Arthropoda	Chordata	arginine binding [GO:0034618]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; dTDP metabolic process [GO:0046072]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; phosphocreatine biosynthetic process [GO:0046314]	dTDP metabolic process [GO:0046072]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	creatine metabolic process [GO:0006600]; muscle contraction [GO:0006936]; phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	arginine binding [GO:0034618]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d4am2a__d3n20b___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d4am2a__d4my7a___1		Metazoa	Proteobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4am4a__d4toew___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4am4b__d4rc8a___1			Proteobacteria	Cyanobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	aldehyde decarbonylase activity [GO:0071771]; aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	aldehyde decarbonylase activity [GO:0071771]; aldehyde oxygenase (deformylating) activity [GO:1990465]; octadecanal decarbonylase activity [GO:0009924]; transition metal ion binding [GO:0046914]
d4am5a__d1fz8c___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d4amhb__d1y8ta1__1	Metazoa		Chordata	Actinobacteria	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cell-cell junction [GO:0005911]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]; cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; cellular response to antibiotic [GO:0071236]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; amyloid precursor protein metabolic process [GO:0042982]; astral microtubule organization [GO:0030953]; bicellular tight junction assembly [GO:0070830]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cellular protein-containing complex localization [GO:0034629]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; cortical microtubule organization [GO:0043622]; embryonic skeletal system morphogenesis [GO:0048704]; endothelial cell proliferation [GO:0001935]; establishment of centrosome localization [GO:0051660]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; hard palate development [GO:0060022]; immunological synapse formation [GO:0001771]; lens development in camera-type eye [GO:0002088]; MAPK cascade [GO:0000165]; membrane raft organization [GO:0031579]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of p38MAPK cascade [GO:1903753]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; peristalsis [GO:0030432]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; regulation of cell shape [GO:0008360]; regulation of membrane potential [GO:0042391]; regulation of myelination [GO:0031641]; regulation of NMDA receptor activity [GO:2000310]; regulation of potassium ion export across plasma membrane [GO:1903764]; regulation of potassium ion import [GO:1903286]; regulation of protein localization to synapse [GO:1902473]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903760]; reproductive structure development [GO:0048608]; smooth muscle tissue development [GO:0048745]; T cell activation [GO:0042110]; T cell cytokine production [GO:0002369]; viral process [GO:0016032]	cellular response to antibiotic [GO:0071236]; pathogenesis [GO:0009405]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	apical plasma membrane [GO:0016324]; basement membrane [GO:0005604]; basolateral plasma membrane [GO:0016323]; bicellular tight junction [GO:0005923]; cell [GO:0005623]; cell-cell junction [GO:0005911]; cell junction [GO:0030054]; cell projection membrane [GO:0031253]; cytoplasm [GO:0005737]; cytoplasmic side of plasma membrane [GO:0009898]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; immunological synapse [GO:0001772]; intercalated disc [GO:0014704]; lateral loop [GO:0043219]; lateral plasma membrane [GO:0016328]; membrane raft [GO:0045121]; microtubule [GO:0005874]; MPP7-DLG1-LIN7 complex [GO:0097025]; myelin sheath abaxonal region [GO:0035748]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; node of Ranvier [GO:0033268]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; sarcolemma [GO:0042383]; synaptic membrane [GO:0097060]	extracellular region [GO:0005576]; integral component of membrane [GO:0016021]	cadherin binding [GO:0045296]; cytoskeletal protein binding [GO:0008092]; guanylate kinase activity [GO:0004385]; ion channel binding [GO:0044325]; L27 domain binding [GO:0097016]; mitogen-activated protein kinase kinase binding [GO:0031434]; molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902]; phosphoprotein phosphatase activity [GO:0004721]; potassium channel regulator activity [GO:0015459]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; structural constituent of postsynaptic density [GO:0098919]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]
d4amub1_d4kh0c1__1			Tenericutes		cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]		arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]		cytoplasm [GO:0005737]		amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	
d4amub2_d4bjhb1__1			Tenericutes	Aquificae	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	dihydroorotase activity [GO:0004151]; zinc ion binding [GO:0008270]; 'de novo' UMP biosynthetic process [GO:0044205]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	'de novo' UMP biosynthetic process [GO:0044205]	cytoplasm [GO:0005737]		amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	dihydroorotase activity [GO:0004151]; zinc ion binding [GO:0008270]
d4amuc1_d2w37c1__1			Tenericutes	Firmicutes	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	arginine catabolic process to ornithine [GO:0019547]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]
d4amva2_d4nnwe___1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d4amvb1_d1t10a___1			Proteobacteria		cytosol [GO:0005829]; carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; protein N-linked glycosylation [GO:0006487]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	carbohydrate derivative binding [GO:0097367]; glutamine-fructose-6-phosphate transaminase (isomerizing) activity [GO:0004360]	glucose-6-phosphate isomerase activity [GO:0004347]
d4amya1_d2bkla1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d4amza1_d3o4gb1__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type peptidase activity [GO:0008236]
d4amza2_d5jz9b___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]				cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	
d4an1a2_d5w8pb1__1	Metazoa		Chordata	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; homoserine O-acetyltransferase activity [GO:0004414]; methionine biosynthetic process [GO:0009086]		methionine biosynthetic process [GO:0009086]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	homoserine O-acetyltransferase activity [GO:0004414]
d4anda__d4s0mh___1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d4anec__d3ngtj___1			Actinobacteria		cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]	ciliary plasm [GO:0097014]; cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; nucleoside diphosphate kinase activity [GO:0004550]
d4anec__d3ztqg___1			Actinobacteria	Aquificae	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; protein autophosphorylation [GO:0046777]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; host cell nucleus [GO:0042025]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nuclease activity [GO:0004518]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d4anfa1_d1akma1__1			Tenericutes	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	arginine biosynthetic process via ornithine [GO:0042450]; citrulline biosynthetic process [GO:0019240]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; metal ion binding [GO:0046872]; ornithine carbamoyltransferase activity [GO:0004585]
d4anfb1_d2qgfc2__1			Tenericutes	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d4anfd2_d1ttha3__1			Tenericutes	Proteobacteria	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine catabolic process to ornithine [GO:0019547]; arginine deiminase pathway [GO:0019546]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d4ankb__d1gkob___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]; hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]; cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	cellular protein metabolic process [GO:0044267]; extracellular matrix organization [GO:0030198]; neutrophil degranulation [GO:0043312]; purine nucleobase metabolic process [GO:0006144]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]; thyroid hormone transport [GO:0070327]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	azurophil granule lumen [GO:0035578]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; protein-containing complex [GO:0032991]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]	hormone activity [GO:0005179]; identical protein binding [GO:0042802]; protein heterodimerization activity [GO:0046982]; thyroid hormone binding [GO:0070324]
d4anwa3_d3bx2a___1	Metazoa	Fungi	Chordata	Ascomycota	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mast cell granule [GO:0042629]; membrane [GO:0016020]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IB [GO:0005944]; plasma membrane [GO:0005886]; 1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; ephrin receptor binding [GO:0046875]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; phosphatidylinositol 3-kinase activity [GO:0035004]; phosphatidylinositol-3,4-bisphosphate 5-kinase activity [GO:0052812]; phosphatidylinositol-4,5-bisphosphate 3-kinase activity [GO:0046934]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; cellular response to cAMP [GO:0071320]; cytokine production [GO:0001816]; dendritic cell chemotaxis [GO:0002407]; endocytosis [GO:0006897]; G protein-coupled receptor signaling pathway [GO:0007186]; hepatocyte apoptotic process [GO:0097284]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mast cell degranulation [GO:0043303]; natural killer cell chemotaxis [GO:0035747]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of triglyceride catabolic process [GO:0010897]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of calcium ion transmembrane transport [GO:1903169]; regulation of cell adhesion mediated by integrin [GO:0033628]; respiratory burst involved in defense response [GO:0002679]; secretory granule localization [GO:0032252]; T cell activation [GO:0042110]; T cell chemotaxis [GO:0010818]; T cell proliferation [GO:0042098]	cytoplasm [GO:0005737]; mRNA binding [GO:0003729]; negative regulation of chromatin silencing involved in replicative cell aging [GO:0001308]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; protein localization [GO:0008104]	adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; cellular response to cAMP [GO:0071320]; cytokine production [GO:0001816]; dendritic cell chemotaxis [GO:0002407]; endocytosis [GO:0006897]; G protein-coupled receptor signaling pathway [GO:0007186]; hepatocyte apoptotic process [GO:0097284]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mast cell degranulation [GO:0043303]; natural killer cell chemotaxis [GO:0035747]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of triglyceride catabolic process [GO:0010897]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; phosphorylation [GO:0016310]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of calcium ion transmembrane transport [GO:1903169]; regulation of cell adhesion mediated by integrin [GO:0033628]; respiratory burst involved in defense response [GO:0002679]; secretory granule localization [GO:0032252]; T cell activation [GO:0042110]; T cell chemotaxis [GO:0010818]; T cell proliferation [GO:0042098]	negative regulation of chromatin silencing involved in replicative cell aging [GO:0001308]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; protein localization [GO:0008104]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mast cell granule [GO:0042629]; membrane [GO:0016020]; phosphatidylinositol 3-kinase complex [GO:0005942]; phosphatidylinositol 3-kinase complex, class IB [GO:0005944]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; ephrin receptor binding [GO:0046875]; identical protein binding [GO:0042802]; kinase activity [GO:0016301]; phosphatidylinositol-3,4-bisphosphate 5-kinase activity [GO:0052812]; phosphatidylinositol 3-kinase activity [GO:0035004]; phosphatidylinositol-4,5-bisphosphate 3-kinase activity [GO:0046934]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]	mRNA binding [GO:0003729]
d4ao5a__d4a6aa___1			Firmicutes	Actinobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d4ao5b1_d1f7qc___1			Firmicutes		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d4ao5c__d4b0ha___1			Firmicutes	Firmicutes	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d4ao5f__d1sm8a___1			Firmicutes	Actinobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d4aocd__d4ut5a___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d4aoob__d1f7ka___1			Firmicutes		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d4aoob__d4ao5d1__1			Firmicutes	Firmicutes	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; protein homotrimerization [GO:0070207]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d4aooc__d2okda___1			Firmicutes		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d4aood__d1xs1d___1			Firmicutes	Proteobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]		cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d4aoza__d1xs1a___1			Firmicutes	Proteobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]		cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d4aozb__d2qlpa___1			Firmicutes	Actinobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d4ap4f__d3pz8d1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]; beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; Rac GTPase binding [GO:0048365]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; collateral sprouting [GO:0048668]; convergent extension involved in neural plate elongation [GO:0022007]; convergent extension involved in organogenesis [GO:0060029]; cytoplasmic microtubule organization [GO:0031122]; dendrite morphogenesis [GO:0048813]; dendritic spine morphogenesis [GO:0060997]; intracellular signal transduction [GO:0035556]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse organization [GO:0099173]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein localization to microtubule [GO:0035372]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cellular protein localization [GO:1903827]; regulation of neurotransmitter levels [GO:0001505]; regulation of protein phosphorylation [GO:0001932]; regulation of synaptic vesicle exocytosis [GO:2000300]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; social behavior [GO:0035176]; synapse organization [GO:0050808]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	axon extension [GO:0048675]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cochlea morphogenesis [GO:0090103]; collateral sprouting [GO:0048668]; convergent extension involved in neural plate elongation [GO:0022007]; convergent extension involved in organogenesis [GO:0060029]; cytoplasmic microtubule organization [GO:0031122]; dendrite morphogenesis [GO:0048813]; dendritic spine morphogenesis [GO:0060997]; intracellular signal transduction [GO:0035556]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; postsynapse organization [GO:0099173]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein localization to microtubule [GO:0035372]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cellular protein localization [GO:1903827]; regulation of neurotransmitter levels [GO:0001505]; regulation of protein phosphorylation [GO:0001932]; regulation of synaptic vesicle exocytosis [GO:2000300]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; social behavior [GO:0035176]; synapse organization [GO:0050808]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	axon [GO:0030424]; clathrin-coated vesicle [GO:0030136]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; lateral plasma membrane [GO:0016328]; microtubule [GO:0005874]; microtubule cytoskeleton [GO:0015630]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; Wnt signalosome [GO:1990909]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	beta-catenin binding [GO:0008013]; enzyme binding [GO:0019899]; frizzled binding [GO:0005109]; identical protein binding [GO:0042802]; protein kinase binding [GO:0019901]; Rac GTPase binding [GO:0048365]
d4apba__d1i0ad___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	structural constituent of eye lens [GO:0005212]; arginine biosynthetic process via ornithine [GO:0042450]	fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	arginine biosynthetic process via ornithine [GO:0042450]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; tricarboxylic acid cycle enzyme complex [GO:0045239]		fumarate hydratase activity [GO:0004333]	structural constituent of eye lens [GO:0005212]
d4apbb__d1tjwa___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; tricarboxylic acid cycle enzyme complex [GO:0045239]; fumarate hydratase activity [GO:0004333]; fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]; arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	fumarate metabolic process [GO:0006106]; tricarboxylic acid cycle [GO:0006099]	arginine biosynthetic process [GO:0006526]; arginine biosynthetic process via ornithine [GO:0042450]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; tricarboxylic acid cycle enzyme complex [GO:0045239]		fumarate hydratase activity [GO:0004333]	argininosuccinate lyase activity [GO:0004056]; structural constituent of eye lens [GO:0005212]
d4apea__d1miqb___1	Fungi		Ascomycota	Apicomplexa	aspartic-type endopeptidase activity [GO:0004190]	integral component of membrane [GO:0016021]; aspartic-type endopeptidase activity [GO:0004190]				integral component of membrane [GO:0016021]	aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d4apea__d2i0ab___1	Fungi		Ascomycota		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d4apqd1_d1ed3e___1	Metazoa	Metazoa	Chordata	Chordata	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; cellular response to iron(III) ion [GO:0071283]; immune response [GO:0006955]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neuron projection development [GO:0010977]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; MHC class I protein complex [GO:0042612]		
d4apre__d4tvhb___1	Fungi		Mucoromycota		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]					aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d4apub__d1k7le___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; ATPase binding [GO:0051117]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclear receptor activity [GO:0004879]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]; cell-cell signaling [GO:0007267]; epithelial cell maturation [GO:0002070]; lung alveolus development [GO:0048286]; negative regulation of gene expression [GO:0010629]; ovulation from ovarian follicle [GO:0001542]; paracrine signaling [GO:0038001]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; regulation of epithelial cell proliferation [GO:0050678]; signal transduction [GO:0007165]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; protein-containing complex binding [GO:0044877]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]; androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	cell-cell signaling [GO:0007267]; epithelial cell maturation [GO:0002070]; lung alveolus development [GO:0048286]; negative regulation of gene expression [GO:0010629]; ovulation from ovarian follicle [GO:0001542]; paracrine signaling [GO:0038001]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; regulation of epithelial cell proliferation [GO:0050678]; signal transduction [GO:0007165]; tertiary branching involved in mammary gland duct morphogenesis [GO:0060748]; transcription initiation from RNA polymerase II promoter [GO:0006367]	androgen receptor signaling pathway [GO:0030521]; bile acid and bile salt transport [GO:0015721]; cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; histone H4 acetylation [GO:0043967]; hypothalamus development [GO:0021854]; labyrinthine layer morphogenesis [GO:0060713]; lactation [GO:0007595]; male gonad development [GO:0008584]; male mating behavior [GO:0060179]; positive regulation of apoptotic process [GO:0043065]; positive regulation of female receptivity [GO:0045925]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]; regulation of cellular response to drug [GO:2001038]; regulation of lipid metabolic process [GO:0019216]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; transcription, DNA-templated [GO:0006351]	cytosol [GO:0005829]; mitochondrial outer membrane [GO:0005741]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]	cytosol [GO:0005829]; neuron projection [GO:0043005]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATPase binding [GO:0051117]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; nuclear receptor activity [GO:0004879]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; signaling receptor binding [GO:0005102]; steroid binding [GO:0005496]; steroid hormone receptor activity [GO:0003707]; zinc ion binding [GO:0008270]	androgen receptor binding [GO:0050681]; aryl hydrocarbon receptor binding [GO:0017162]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; estrogen receptor binding [GO:0030331]; histone acetyltransferase activity [GO:0004402]; nuclear hormone receptor binding [GO:0035257]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; progesterone receptor binding [GO:0033142]; protein-containing complex binding [GO:0044877]; protein dimerization activity [GO:0046983]; protein N-terminus binding [GO:0047485]; retinoid X receptor binding [GO:0046965]; RNA polymerase II regulatory region DNA binding [GO:0001012]; transcription coactivator activity [GO:0003713]
d4apya__d1j51b___1			Actinobacteria	Proteobacteria	cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; cholesterol catabolic process [GO:0006707]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	cholesterol catabolic process [GO:0006707]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	cholest-4-en-3-one 26-monooxygenase activity [GO:0036199]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d4apz1__d2hxba___1			Firmicutes	Euryarchaeota	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d4apz2__d1f7na___1			Firmicutes		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; dUTP diphosphatase activity [GO:0004170]; exoribonuclease H activity [GO:0004533]; magnesium ion binding [GO:0000287]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; zinc ion binding [GO:0008270]
d4apz3__d2okdb___1			Firmicutes		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d4apz4__d4a6al___1			Firmicutes	Actinobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase (dUMP-forming) activity [GO:0033973]; dCTP deaminase activity [GO:0008829]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]
d4apzb__d3c3ia___1			Firmicutes		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d4apzc__d4ooqb___1		Viridiplantae	Firmicutes	Streptophyta	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	DNA repair [GO:0006281]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]		cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d4apzd__d4wrkc___1			Firmicutes		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d4apze__d1xs1b___1			Firmicutes	Proteobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]		cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d4apzf__d2bt1a1__1			Firmicutes		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP metabolic process [GO:0046080]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]
d4apzk__d1mq7a___1			Firmicutes	Actinobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; dUTP metabolic process [GO:0046080]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d4apzn__d2j4qa___1			Firmicutes	Proteobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]		cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d4apzo__d2bt1a2__1			Firmicutes		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]; dUTP metabolic process [GO:0046080]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP metabolic process [GO:0046080]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; metal ion binding [GO:0046872]
d4apzr__d2v9xg___1			Firmicutes	Proteobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]		cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d4apzu__d2j4ha___1			Firmicutes	Proteobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]		cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d4apzv__d3c3ic___1			Firmicutes		dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]			dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]
d4aq1b1_d1j88c1__1		Metazoa	Firmicutes	Chordata	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]		Fc-epsilon receptor signaling pathway [GO:0038095]		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	IgE binding [GO:0019863]
d4aq2a__d4kwja___1		Metazoa	Proteobacteria	Chordata	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	cytosol [GO:0005829]; cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; cysteine metabolic process [GO:0006534]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; lactation [GO:0007595]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	cysteine metabolic process [GO:0006534]; lactation [GO:0007595]; L-cysteine catabolic process [GO:0019448]; L-cysteine metabolic process [GO:0046439]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to organonitrogen compound [GO:0010243]; taurine biosynthetic process [GO:0042412]	protein-DNA complex [GO:0032993]	cytosol [GO:0005829]	DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	cysteine dioxygenase activity [GO:0017172]; ferrous iron binding [GO:0008198]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d4aq2k__d4l2na___1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]; 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]	L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]	protein-DNA complex [GO:0032993]		DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	3-hydroxyanthranilate 3,4-dioxygenase activity [GO:0000334]; ferrous iron binding [GO:0008198]
d4aq6c__d4ewda___1		Metazoa	Proteobacteria	Chordata	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; quercetin 2,3-dioxygenase activity [GO:0008127]; transcription coregulator activity [GO:0003712]; digestion [GO:0007586]; monocyte differentiation [GO:0030224]; transcription by RNA polymerase II [GO:0006366]	L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	digestion [GO:0007586]; monocyte differentiation [GO:0030224]; transcription by RNA polymerase II [GO:0006366]	protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	metal ion binding [GO:0046872]; quercetin 2,3-dioxygenase activity [GO:0008127]; transcription coregulator activity [GO:0003712]
d4aq6d__d1qxrb___1			Proteobacteria	Euryarchaeota	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	protein-DNA complex [GO:0032993]	cytoplasm [GO:0005737]	DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	glucose-6-phosphate isomerase activity [GO:0004347]; iron ion binding [GO:0005506]
d4aq6h__d4tlfa___1			Proteobacteria	Proteobacteria	protein-DNA complex [GO:0032993]; DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; oxidation-reduction process [GO:0055114]	L-phenylalanine catabolic process [GO:0006559]; negative regulation of transcription, DNA-templated [GO:0045892]; tyrosine catabolic process [GO:0006572]	oxidation-reduction process [GO:0055114]	protein-DNA complex [GO:0032993]		DNA-binding transcription repressor activity [GO:0001217]; homogentisate 1,2-dioxygenase activity [GO:0004411]; iron ion binding [GO:0005506]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	ferrous iron binding [GO:0008198]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]
d4aqia__d3cgab___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; calcium ion binding [GO:0005509]; protein self-association [GO:0043621]; transition metal ion binding [GO:0046914]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; actin binding [GO:0003779]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]; epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]		epithelial to mesenchymal transition [GO:0001837]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	cytosol [GO:0005829]	collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; neuron projection [GO:0043005]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	calcium ion binding [GO:0005509]; protein self-association [GO:0043621]; transition metal ion binding [GO:0046914]	actin binding [GO:0003779]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; RAGE receptor binding [GO:0050786]; RNA binding [GO:0003723]; transition metal ion binding [GO:0046914]
d4aqja__d1nuba1__1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	basement membrane [GO:0005604]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; nuclear matrix [GO:0016363]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; platelet alpha granule membrane [GO:0031092]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; extracellular matrix binding [GO:0050840]; bone development [GO:0060348]; cellular response to growth factor stimulus [GO:0071363]; extracellular matrix organization [GO:0030198]; heart development [GO:0007507]; inner ear development [GO:0048839]; lung development [GO:0030324]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; ossification [GO:0001503]; pigmentation [GO:0043473]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; receptor-mediated endocytosis [GO:0006898]; regulation of cell morphogenesis [GO:0022604]; regulation of synapse organization [GO:0050807]; response to cadmium ion [GO:0046686]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to gravity [GO:0009629]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; wound healing [GO:0042060]	angiogenesis [GO:0001525]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; antimicrobial humoral response [GO:0019730]; defense response to Gram-negative bacterium [GO:0050829]; epidermis development [GO:0008544]; innate immune response [GO:0045087]; keratinocyte differentiation [GO:0030216]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of T cell chemotaxis [GO:0010820]; response to lipopolysaccharide [GO:0032496]; response to reactive oxygen species [GO:0000302]; sequestering of metal ion [GO:0051238]	bone development [GO:0060348]; cellular response to growth factor stimulus [GO:0071363]; extracellular matrix organization [GO:0030198]; heart development [GO:0007507]; inner ear development [GO:0048839]; lung development [GO:0030324]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell proliferation [GO:0001937]; ossification [GO:0001503]; pigmentation [GO:0043473]; platelet degranulation [GO:0002576]; positive regulation of endothelial cell migration [GO:0010595]; receptor-mediated endocytosis [GO:0006898]; regulation of cell morphogenesis [GO:0022604]; regulation of synapse organization [GO:0050807]; response to cadmium ion [GO:0046686]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to glucocorticoid [GO:0051384]; response to gravity [GO:0009629]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; wound healing [GO:0042060]	azurophil granule lumen [GO:0035578]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; nucleus [GO:0005634]	basement membrane [GO:0005604]; cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; nuclear matrix [GO:0016363]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; platelet alpha granule membrane [GO:0031092]	calcium ion binding [GO:0005509]; RAGE receptor binding [GO:0050786]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; extracellular matrix binding [GO:0050840]
d4aqpa1_d1v06a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; poly(G) binding [GO:0034046]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; protein self-association [GO:0043621]; anatomical structure development [GO:0048856]; brain development [GO:0007420]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; nuclear export [GO:0051168]; regulation of transcription, DNA-templated [GO:0006355]; RNA processing [GO:0006396]; social behavior [GO:0035176]	nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; negative regulation of lipid transport [GO:0032369]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of potassium ion transport [GO:0043268]; Wnt signaling pathway [GO:0016055]	anatomical structure development [GO:0048856]; brain development [GO:0007420]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; nuclear export [GO:0051168]; regulation of transcription, DNA-templated [GO:0006355]; RNA processing [GO:0006396]; social behavior [GO:0035176]	negative regulation of lipid transport [GO:0032369]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of potassium ion transport [GO:0043268]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nuclear inclusion body [GO:0042405]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	DNA binding [GO:0003677]; identical protein binding [GO:0042802]; poly(G) binding [GO:0034046]; poly(U) RNA binding [GO:0008266]; protein C-terminus binding [GO:0008022]; protein self-association [GO:0043621]	DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]
d4aqra__d1rwya___1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytosol [GO:0005829]; calcium ion binding [GO:0005509]; calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; regulation of photomorphogenesis [GO:0010099]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]; calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; cochlea development [GO:0090102]	calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]; regulation of photomorphogenesis [GO:0010099]	cochlea development [GO:0090102]	cytosol [GO:0005829]	cuticular plate [GO:0032437]; cytoplasm [GO:0005737]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; stereocilium [GO:0032420]; terminal bouton [GO:0043195]	calcium ion binding [GO:0005509]	calcium ion binding [GO:0005509]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]
d4arxa3_d1bgmk3__1			Firmicutes		signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]		sporulation resulting in formation of a cellular spore [GO:0030435]				signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	
d4arxa3_d1wcqa2__1			Firmicutes	Actinobacteria	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	extracellular region [GO:0005576]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metabolic process [GO:0008152]	sporulation resulting in formation of a cellular spore [GO:0030435]	metabolic process [GO:0008152]		extracellular region [GO:0005576]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d4arxb3_d3vdad1__1			Firmicutes	Proteobacteria	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	sporulation resulting in formation of a cellular spore [GO:0030435]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d4arxd2_d1w99a2__1			Firmicutes	Firmicutes	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]			signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d4arxd3_d3etpa1__1		Metazoa	Firmicutes	Chordata	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]; amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein tyrosine kinase activity [GO:0004713]; protein-containing complex binding [GO:0044877]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane-ephrin receptor activity [GO:0005005]; angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; urogenital system development [GO:0001655]	sporulation resulting in formation of a cellular spore [GO:0030435]	angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell morphogenesis [GO:0000902]; central nervous system projection neuron axonogenesis [GO:0021952]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; inactivation of MAPKK activity [GO:0051389]; inner ear morphogenesis [GO:0042472]; learning [GO:0007612]; learning or memory [GO:0007611]; negative regulation of axonogenesis [GO:0050771]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of NMDA glutamate receptor activity [GO:1904782]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; neuron projection retraction [GO:0106028]; optic nerve morphogenesis [GO:0021631]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphorylation [GO:0016310]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic plasticity [GO:0031915]; postsynaptic membrane assembly [GO:0097104]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of body fluid levels [GO:0050878]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synapse assembly [GO:0051963]; retinal ganglion cell axon guidance [GO:0031290]; roof of mouth development [GO:0060021]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission [GO:0099557]; urogenital system development [GO:0001655]		axon [GO:0030424]; dendrite [GO:0030425]; glutamatergic synapse [GO:0098978]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; synapse [GO:0045202]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	amyloid-beta binding [GO:0001540]; ATP binding [GO:0005524]; axon guidance receptor activity [GO:0008046]; ephrin receptor activity [GO:0005003]; identical protein binding [GO:0042802]; protein-containing complex binding [GO:0044877]; protein tyrosine kinase activity [GO:0004713]; signaling receptor activity [GO:0038023]; signaling receptor binding [GO:0005102]; transmembrane-ephrin receptor activity [GO:0005005]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]
d4arya3_d3zyha___1			Firmicutes	Proteobacteria	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]; carbohydrate binding [GO:0030246]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	sporulation resulting in formation of a cellular spore [GO:0030435]	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; periplasmic space [GO:0042597]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	carbohydrate binding [GO:0030246]
d4aryc3_d3k77d___1		Metazoa	Firmicutes	Chordata	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]; base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]	sporulation resulting in formation of a cellular spore [GO:0030435]	base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; cerebellum morphogenesis [GO:0021587]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; hippocampus development [GO:0021766]; negative regulation of protection from non-homologous end joining at telomere [GO:1905765]; negative regulation of protein ADP-ribosylation [GO:0010836]; nucleotide-excision repair, DNA gap filling [GO:0006297]; positive regulation of DNA ligase activity [GO:1904877]; positive regulation of single strand break repair [GO:1903518]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to drug [GO:0042493]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; telomeric DNA-containing double minutes formation [GO:0061819]; transcription-coupled nucleotide-excision repair [GO:0006283]; voluntary musculoskeletal movement [GO:0050882]		ERCC4-ERCC1 complex [GO:0070522]; nuclear chromatin [GO:0000790]; nuclear chromosome, telomeric region [GO:0000784]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	3' overhang single-stranded DNA endodeoxyribonuclease activity [GO:1990599]; enzyme binding [GO:0019899]; oxidized DNA binding [GO:0032356]
d4aryd2_d4qx1a2__1			Firmicutes	Firmicutes	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]; sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]	sporulation resulting in formation of a cellular spore [GO:0030435]			signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]	signaling receptor binding [GO:0005102]; toxin activity [GO:0090729]
d4asaa__d4xiqa___1	Fungi	Metazoa	Ascomycota	Chordata	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]
d4asie1_d2qq3c___1	Metazoa		Chordata	Firmicutes	actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; acetyl-CoA metabolic process [GO:0006084]; carnitine shuttle [GO:0006853]; cellular response to prostaglandin E stimulus [GO:0071380]; fatty acid biosynthetic process [GO:0006633]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lipid homeostasis [GO:0055088]; malonyl-CoA biosynthetic process [GO:2001295]; positive regulation of cellular metabolic process [GO:0031325]; protein homotetramerization [GO:0051289]; protein metabolic process [GO:0019538]; regulation of cholesterol biosynthetic process [GO:0045540]; tissue homeostasis [GO:0001894]	catalytic activity [GO:0003824]	acetyl-CoA metabolic process [GO:0006084]; carnitine shuttle [GO:0006853]; cellular response to prostaglandin E stimulus [GO:0071380]; fatty acid biosynthetic process [GO:0006633]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lipid homeostasis [GO:0055088]; malonyl-CoA biosynthetic process [GO:2001295]; positive regulation of cellular metabolic process [GO:0031325]; protein homotetramerization [GO:0051289]; protein metabolic process [GO:0019538]; regulation of cholesterol biosynthetic process [GO:0045540]; tissue homeostasis [GO:0001894]		actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; fibrillar center [GO:0001650]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]
d4asif1_d1wz8a1__1	Metazoa		Chordata	Deinococcus-Thermus	actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; fibrillar center [GO:0001650]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; acetyl-CoA metabolic process [GO:0006084]; carnitine shuttle [GO:0006853]; cellular response to prostaglandin E stimulus [GO:0071380]; fatty acid biosynthetic process [GO:0006633]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lipid homeostasis [GO:0055088]; malonyl-CoA biosynthetic process [GO:2001295]; positive regulation of cellular metabolic process [GO:0031325]; protein homotetramerization [GO:0051289]; protein metabolic process [GO:0019538]; regulation of cholesterol biosynthetic process [GO:0045540]; tissue homeostasis [GO:0001894]	catalytic activity [GO:0003824]	acetyl-CoA metabolic process [GO:0006084]; carnitine shuttle [GO:0006853]; cellular response to prostaglandin E stimulus [GO:0071380]; fatty acid biosynthetic process [GO:0006633]; fatty-acyl-CoA biosynthetic process [GO:0046949]; lipid homeostasis [GO:0055088]; malonyl-CoA biosynthetic process [GO:2001295]; positive regulation of cellular metabolic process [GO:0031325]; protein homotetramerization [GO:0051289]; protein metabolic process [GO:0019538]; regulation of cholesterol biosynthetic process [GO:0045540]; tissue homeostasis [GO:0001894]		actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; fibrillar center [GO:0001650]		acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]	catalytic activity [GO:0003824]
d4asjb__d1o7ra___1			Proteobacteria		glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]				glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	
d4asjd__d5vqma___1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]		dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]				glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	
d4asua1_d2jj2d1__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d4asua1_d5knce1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d4asua3_d5hkkl3__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d4asuc1_d3vr6e1__1	Metazoa		Chordata	Firmicutes	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]; sodium ion transport [GO:0006814]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]		ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d4asud3_d3b2qb3__1	Metazoa		Chordata	Euryarchaeota	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; plasma membrane ATP synthesis coupled proton transport [GO:0042777]	ATP synthesis coupled proton transport [GO:0015986]	plasma membrane ATP synthesis coupled proton transport [GO:0042777]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d4asue2_d2jj2b2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d4asuf1_d1bmfa2__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d4asuf3_d4yxwa3__1	Metazoa	Metazoa	Chordata	Chordata	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	ATP synthesis coupled proton transport [GO:0015986]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d4asya__d2agdb___1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; keratan sulfate biosynthetic process [GO:0018146]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; neutrophil degranulation [GO:0043312]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		azurophil granule membrane [GO:0035577]; basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi membrane [GO:0000139]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; galactosyltransferase activity [GO:0008378]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d4asyb__d5vmka1__1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytoplasm [GO:0005737]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytoplasm [GO:0005737]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d4at1a2_d4jqob1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]; arginine biosynthetic process [GO:0006526]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	arginine biosynthetic process [GO:0006526]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; ornithine carbamoyltransferase activity [GO:0004585]
d4at1c2_d1za2a1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]; 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]; nitrogen compound metabolic process [GO:0006807]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]	amino acid binding [GO:0016597]; aspartate carbamoyltransferase activity [GO:0004070]; identical protein binding [GO:0042802]
d4at6b1_d2vyrg___1		Metazoa		Chordata		nucleoplasm [GO:0005654]; nucleus [GO:0005634]; enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]; atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; protein-containing complex assembly [GO:0065003]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]		atrial septum development [GO:0003283]; atrioventricular valve morphogenesis [GO:0003181]; cell population proliferation [GO:0008283]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocardial cushion morphogenesis [GO:0003203]; G0 to G1 transition [GO:0045023]; heart valve development [GO:0003170]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of signal transduction by p53 class mediator [GO:1901796]; ventricular septum development [GO:0003281]		nucleoplasm [GO:0005654]; nucleus [GO:0005634]		enzyme binding [GO:0019899]; zinc ion binding [GO:0008270]
d4at6d1_d1ngxl1__1												
d4at6f1_d5d4qb2__1		Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4at6i1_d1bjmb1__1												
d4at6i1_d4pjeb1__1		Metazoa		Chordata		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]		cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4at6i2_d5gs1m___1												
d4at6n2_d5ibtl2__1												
d4at6p2_d1j86b2__1		Metazoa		Chordata		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; IgE binding [GO:0019863]; Fc-epsilon receptor signaling pathway [GO:0038095]		Fc-epsilon receptor signaling pathway [GO:0038095]		cell surface [GO:0009986]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]		IgE binding [GO:0019863]
d4atfb__d3o5sa___1			Bacteroidetes	Firmicutes	cell outer membrane [GO:0009279]; beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; licheninase activity [GO:0042972]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	cell outer membrane [GO:0009279]	extracellular region [GO:0005576]	beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]	licheninase activity [GO:0042972]
d4atfc1_d1jxnd___1		Viridiplantae	Bacteroidetes	Streptophyta	cell outer membrane [GO:0009279]; beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]; carbohydrate metabolic process [GO:0005975]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]		cell outer membrane [GO:0009279]		beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d4atfd1_d3wvja___1			Bacteroidetes	Firmicutes	cell outer membrane [GO:0009279]; beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]; carbohydrate metabolic process [GO:0005975]	licheninase activity [GO:0042972]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	cell outer membrane [GO:0009279]		beta-agarase activity [GO:0033916]; protein homodimerization activity [GO:0042803]	licheninase activity [GO:0042972]
d4atjb1_d1bema___1	Viridiplantae	Fungi	Streptophyta	Ascomycota	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]; vacuole [GO:0005773]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d4atjb1_d3x16a1__1	Viridiplantae		Streptophyta	Cyanobacteria	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d4atta__d3jwnn2__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	pilus [GO:0009289]	mannose binding [GO:0005537]	
d4au0b__d5jx5c___1	Fungi	Fungi	Ascomycota	Chytridiomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d4au9b__d1iujb___1	Fungi		Basidiomycota	Deinococcus-Thermus	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	metal ion binding [GO:0046872]			extracellular region [GO:0005576]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	metal ion binding [GO:0046872]
d4auqa__d1m4pa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]		protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	
d4auqd__d1yf9b___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; ubiquitin conjugating enzyme activity [GO:0061631]; ubiquitin-dependent protein catabolic process [GO:0006511]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]		protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	ATP binding [GO:0005524]; ligase activity [GO:0016874]; ubiquitin conjugating enzyme activity [GO:0061631]
d4auqf__d5chwi1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to bacterium [GO:0009617]; response to type I interferon [GO:0034340]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d4auya__d4xo9a1__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]	mannose binding [GO:0005537]	mannose binding [GO:0005537]
d4auya__d4z3ga1__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d4auyb__d1klfp2__1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]	mannose binding [GO:0005537]	mannose binding [GO:0005537]
d4av5c__d2uy6c___1			Proteobacteria	Proteobacteria	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	outer membrane-bounded periplasmic space [GO:0030288]; cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell wall organization [GO:0071555]; chaperone-mediated protein folding [GO:0061077]; pilus organization [GO:0043711]	host cell membrane [GO:0033644]; pilus [GO:0009289]	outer membrane-bounded periplasmic space [GO:0030288]	mannose binding [GO:0005537]	
d4av7a2_d3bkra___1		Metazoa	Proteobacteria	Arthropoda	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]						metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	
d4av7f1_d5v8sa1__1			Proteobacteria	Thermotogae	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]					metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d4av7f2_d2i00f1__1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	N-acetyltransferase activity [GO:0008080]					metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	N-acetyltransferase activity [GO:0008080]
d4avhb__d1n67a2__1			Proteobacteria	Firmicutes	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]; pathogenesis [GO:0009405]	host cell membrane [GO:0033644]; pilus [GO:0009289]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]	mannose binding [GO:0005537]	
d4avpd__d1z9cd___1	Metazoa		Chordata	Firmicutes	nuclear chromatin [GO:0000790]; nucleus [GO:0005634]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; axon guidance [GO:0007411]; cell differentiation [GO:0030154]; mechanosensory behavior [GO:0007638]; muscle organ development [GO:0007517]; peripheral nervous system neuron development [GO:0048935]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]	cytoplasm [GO:0005737]; DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]; regulation of transcription, DNA-templated [GO:0006355]	axon guidance [GO:0007411]; cell differentiation [GO:0030154]; mechanosensory behavior [GO:0007638]; muscle organ development [GO:0007517]; peripheral nervous system neuron development [GO:0048935]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366]	regulation of transcription, DNA-templated [GO:0006355]	nuclear chromatin [GO:0000790]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]	DNA-binding transcription factor activity [GO:0003700]; transcription regulatory region DNA binding [GO:0044212]
d4avsa__d3naja2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	
d4avsd__d1qnwc___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d4avvb__d5u38a___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d4avvd__d3l2ym___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d4avxa1_d1ujja___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; ESCRT-0 complex [GO:0033565]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; multivesicular body membrane [GO:0032585]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; ubiquitin-like protein ligase binding [GO:0044389]; endosomal transport [GO:0016197]; macroautophagy [GO:0016236]; membrane invagination [GO:0010324]; membrane organization [GO:0061024]; multivesicular body assembly [GO:0036258]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of gene expression [GO:0010628]; protein deubiquitination [GO:0016579]; protein localization to membrane [GO:0072657]; protein targeting to lysosome [GO:0006622]; regulation of MAP kinase activity [GO:0043405]; regulation of protein catabolic process [GO:0042176]; signal transduction [GO:0007165]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]; amyloid precursor protein catabolic process [GO:0042987]; amyloid-beta metabolic process [GO:0050435]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	endosomal transport [GO:0016197]; macroautophagy [GO:0016236]; membrane invagination [GO:0010324]; membrane organization [GO:0061024]; multivesicular body assembly [GO:0036258]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of gene expression [GO:0010628]; protein deubiquitination [GO:0016579]; protein localization to membrane [GO:0072657]; protein targeting to lysosome [GO:0006622]; regulation of MAP kinase activity [GO:0043405]; regulation of protein catabolic process [GO:0042176]; signal transduction [GO:0007165]	amyloid-beta metabolic process [GO:0050435]; amyloid precursor protein catabolic process [GO:0042987]; cellular protein metabolic process [GO:0044267]; cellular response to amyloid-beta [GO:1904646]; cellular response to copper ion [GO:0071280]; cellular response to manganese ion [GO:0071287]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; membrane protein ectodomain proteolysis [GO:0006509]; positive regulation of neuron apoptotic process [GO:0043525]; prepulse inhibition [GO:0060134]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; regulation of synaptic vesicle exocytosis [GO:2000300]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]	cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endosome [GO:0005768]; ESCRT-0 complex [GO:0033565]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; multivesicular body membrane [GO:0032585]	axon [GO:0030424]; cell surface [GO:0009986]; cytoplasmic vesicle membrane [GO:0030659]; dendrite [GO:0030425]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endosome [GO:0005768]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi-associated vesicle lumen [GO:0070931]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body [GO:0005771]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; ubiquitin-like protein ligase binding [GO:0044389]	amyloid-beta binding [GO:0001540]; aspartic-type endopeptidase activity [GO:0004190]; beta-aspartyl-peptidase activity [GO:0008798]; endopeptidase activity [GO:0004175]; enzyme binding [GO:0019899]; peptidase activity [GO:0008233]
d4avyb__d1bxgb1__1			Proteobacteria	Actinobacteria	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; oxidation-reduction process [GO:0055114]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]	oxidation-reduction process [GO:0055114]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine catabolic process [GO:0006559]			nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]	nucleotide binding [GO:0000166]; phenylalanine dehydrogenase activity [GO:0050175]
d4aw3a__d6cp4a___1			Actinobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d4aw4b1_d2wqvb1__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; lipid binding [GO:0008289]; pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	pathogenesis [GO:0009405]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	heparin binding [GO:0008201]; lipid binding [GO:0008289]	heparin binding [GO:0008201]; lipid binding [GO:0008289]
d4awna__d3fzia1__1	Metazoa		Chordata	Euryarchaeota	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]; apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]	apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]	DNA repair [GO:0006281]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]		actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]	DNA binding [GO:0003677]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
d4awna__d4lndb___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]; actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]; apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]; 3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948]	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, base-free sugar-phosphate removal [GO:0006286]; cell redox homeostasis [GO:0045454]; cellular response to cAMP [GO:0071320]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide hormone stimulus [GO:0071375]; DNA demethylation [GO:0080111]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of smooth muscle cell migration [GO:0014912]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]; telomere maintenance [GO:0000723]; telomere maintenance via base-excision repair [GO:0097698]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nuclear envelope [GO:0005635]; nucleus [GO:0005634]	cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; mitochondrion [GO:0005739]; nuclear chromosome, telomeric region [GO:0000784]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; ribosome [GO:0005840]; transcription factor complex [GO:0005667]	actin binding [GO:0003779]; deoxyribonuclease activity [GO:0004536]; deoxyribonuclease I activity [GO:0004530]; DNA binding [GO:0003677]	3'-5' exonuclease activity [GO:0008408]; chromatin DNA binding [GO:0031490]; class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0140078]; damaged DNA binding [GO:0003684]; DNA-(apurinic or apyrimidinic site) endonuclease activity [GO:0003906]; DNA binding [GO:0003677]; double-stranded DNA 3'-5' exodeoxyribonuclease activity [GO:0008311]; double-stranded DNA exodeoxyribonuclease activity [GO:0008309]; double-stranded telomeric DNA binding [GO:0003691]; endodeoxyribonuclease activity [GO:0004520]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; NF-kappaB binding [GO:0051059]; oxidoreductase activity [GO:0016491]; phosphodiesterase I activity [GO:0004528]; phosphoric diester hydrolase activity [GO:0008081]; protein-containing complex binding [GO:0044877]; RNA binding [GO:0003723]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; site-specific endodeoxyribonuclease activity, specific for altered base [GO:0016890]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; uracil DNA N-glycosylase activity [GO:0004844]
d4awsa__d3w70b___1			Proteobacteria		cytosol [GO:0005829]; FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d4awta__d3w2mb___1			Proteobacteria		cytosol [GO:0005829]; FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	cytoplasm [GO:0005737]; dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]; 'de novo' UMP biosynthetic process [GO:0044205]		'de novo' UMP biosynthetic process [GO:0044205]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	FMN binding [GO:0010181]; oxidoreductase activity [GO:0016491]	dihydroorotate dehydrogenase (fumarate) activity [GO:1990663]
d4awzc__d3lvzb___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d4ax6a__d3voha1__1	Fungi	Fungi	Ascomycota	Basidiomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d4ax6b__d3a9ba1__1	Fungi	Fungi	Ascomycota	Basidiomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]		cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d4ax7a__d5xcza___1	Fungi	Fungi	Ascomycota	Basidiomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; identical protein binding [GO:0042802]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d4axha1_d1ycfd2__1			Proteobacteria	Firmicutes	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]					metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	electron transfer activity [GO:0009055]; FMN binding [GO:0010181]; metal ion binding [GO:0046872]
d4axha1_d4rbsa___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]	metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d4axja__d4qifi___1			Firmicutes	Proteobacteria								
d4axjc__d4ox6b___1			Firmicutes	Cyanobacteria								
d4axta__d4i7mb1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d4ay3a__d2nsja___1			Firmicutes	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	cytosol [GO:0005829]; 5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; identical protein binding [GO:0042802]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]		cytosol [GO:0005829]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; identical protein binding [GO:0042802]
d4ayuc__d1utwb2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	
d4ayud__d1sfya___1	Metazoa	Viridiplantae	Chordata	Streptophyta	blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]	carbohydrate binding [GO:0030246]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; chaperone-mediated protein complex assembly [GO:0051131]; complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation by host of viral exo-alpha-sialidase activity [GO:0044869]; negative regulation by host of viral glycoprotein metabolic process [GO:0044871]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of exo-alpha-sialidase activity [GO:1903016]; negative regulation of glycoprotein metabolic process [GO:1903019]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral process [GO:0048525]; negative regulation of wound healing [GO:0061045]; protein folding [GO:0006457]		blood microparticle [GO:0072562]; collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]		calcium ion binding [GO:0005509]; carbohydrate binding [GO:0030246]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; unfolded protein binding [GO:0051082]; virion binding [GO:0046790]	carbohydrate binding [GO:0030246]
d4az9a1_d2reaa1__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic vesicle membrane [GO:0030659]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]; protein transport [GO:0015031]	clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; 1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; phosphatidylinositol 3-kinase activity [GO:0035004]; phosphatidylinositol binding [GO:0035091]; clathrin coat assembly [GO:0048268]; endocytosis [GO:0006897]; epidermal growth factor receptor signaling pathway [GO:0007173]; exocytosis [GO:0006887]; insulin receptor signaling pathway [GO:0008286]; membrane organization [GO:0061024]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; vascular smooth muscle contraction [GO:0014829]	protein transport [GO:0015031]	clathrin coat assembly [GO:0048268]; endocytosis [GO:0006897]; epidermal growth factor receptor signaling pathway [GO:0007173]; exocytosis [GO:0006887]; insulin receptor signaling pathway [GO:0008286]; membrane organization [GO:0061024]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; vascular smooth muscle contraction [GO:0014829]	cytoplasmic vesicle membrane [GO:0030659]	clathrin-coated vesicle [GO:0030136]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314]	1-phosphatidylinositol-3-kinase activity [GO:0016303]; 1-phosphatidylinositol-4-phosphate 3-kinase activity [GO:0035005]; ATP binding [GO:0005524]; phosphatidylinositol 3-kinase activity [GO:0035004]; phosphatidylinositol binding [GO:0035091]
d4azda1_d3cf1a1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; aspartate 1-decarboxylase activity [GO:0004068]; alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; protein-containing complex binding [GO:0044877]; signaling receptor binding [GO:0005102]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin-specific protease binding [GO:1990381]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ER-associated misfolded protein catabolic process [GO:0071712]; ERAD pathway [GO:0036503]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	alanine biosynthetic process [GO:0006523]; pantothenate biosynthetic process [GO:0015940]; protein autoprocessing [GO:0016540]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aggresome assembly [GO:0070842]; ATP metabolic process [GO:0046034]; autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; cellular response to arsenite ion [GO:1903843]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to heat [GO:0034605]; double-strand break repair [GO:0006302]; endoplasmic reticulum stress-induced pre-emptive quality control [GO:0061857]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; flavin adenine dinucleotide catabolic process [GO:0072389]; macroautophagy [GO:0016236]; mitotic spindle disassembly [GO:0051228]; NADH metabolic process [GO:0006734]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Lys63-specific deubiquitinase activity [GO:1903007]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of oxidative phosphorylation [GO:1903862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein K63-linked deubiquitination [GO:1903006]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; regulation of aerobic respiration [GO:1903715]; regulation of synapse organization [GO:0050807]; retrograde protein transport, ER to cytosol [GO:0030970]; stress granule disassembly [GO:0035617]; translesion synthesis [GO:0019985]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral genome replication [GO:0019079]	cytosol [GO:0005829]	ATPase complex [GO:1904949]; cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; Derlin-1 retrotranslocation complex [GO:0036513]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; intracellular membrane-bounded organelle [GO:0043231]; lipid droplet [GO:0005811]; myelin sheath [GO:0043209]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; proteasome complex [GO:0000502]; protein-containing complex [GO:0032991]; site of double-strand break [GO:0035861]; synapse [GO:0045202]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; VCP-NSFL1C complex [GO:1990730]	aspartate 1-decarboxylase activity [GO:0004068]	ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; BAT3 complex binding [GO:1904288]; deubiquitinase activator activity [GO:0035800]; identical protein binding [GO:0042802]; K48-linked polyubiquitin modification-dependent protein binding [GO:0036435]; lipid binding [GO:0008289]; MHC class I protein binding [GO:0042288]; polyubiquitin modification-dependent protein binding [GO:0031593]; protein-containing complex binding [GO:0044877]; protein domain specific binding [GO:0019904]; protein phosphatase binding [GO:0019903]; signaling receptor binding [GO:0005102]; ubiquitin-like protein ligase binding [GO:0044389]; ubiquitin protein ligase binding [GO:0031625]; ubiquitin-specific protease binding [GO:1990381]
d4azja__d4wyda___1			Firmicutes	Actinobacteria	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	L-serine biosynthetic process [GO:0006564]	biotin biosynthetic process [GO:0009102]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]
d4azka__d5efsa___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]	mitochondrial matrix [GO:0005759]; 2-aminoadipate transaminase activity [GO:0047536]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; 2-oxoglutarate metabolic process [GO:0006103]; alpha-amino acid metabolic process [GO:1901605]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine catabolic process [GO:0006554]; tryptophan catabolic process [GO:0006569]	L-serine biosynthetic process [GO:0006564]	2-oxoglutarate metabolic process [GO:0006103]; alpha-amino acid metabolic process [GO:1901605]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine catabolic process [GO:0006554]; tryptophan catabolic process [GO:0006569]	cytoplasm [GO:0005737]	mitochondrial matrix [GO:0005759]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]	2-aminoadipate transaminase activity [GO:0047536]; kynurenine-oxoglutarate transaminase activity [GO:0016212]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d4azkb__d4o6zc___1			Firmicutes	Apicomplexa	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]	apicoplast [GO:0020011]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]; cellular response to tetrahydrofolate [GO:1904482]; D-serine metabolic process [GO:0070178]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	L-serine biosynthetic process [GO:0006564]	cellular response to tetrahydrofolate [GO:1904482]; D-serine metabolic process [GO:0070178]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine catabolic process [GO:0006565]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	cytoplasm [GO:0005737]	apicoplast [GO:0020011]; cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]	amino acid binding [GO:0016597]; cobalt ion binding [GO:0050897]; glycine hydroxymethyltransferase activity [GO:0004372]; methyltransferase activity [GO:0008168]; pyridoxal phosphate binding [GO:0030170]; serine binding [GO:0070905]; zinc ion binding [GO:0008270]
d4azmb__d1kqxa___1	Metazoa	Metazoa	Chordata	Chordata	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]; epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	lipid binding [GO:0008289]	epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]		azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]		fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]	lipid binding [GO:0008289]
d4azoa1_d3em0b1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; retinoic acid binding [GO:0001972]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]	bile acid binding [GO:0032052]; lipid binding [GO:0008289]	glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]		cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]		fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; retinoic acid binding [GO:0001972]	bile acid binding [GO:0032052]; lipid binding [GO:0008289]
d4azqa1_d4lktb1__1	Metazoa	Metazoa	Chordata	Chordata	cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; retinoic acid binding [GO:0001972]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]; epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]	epidermis development [GO:0008544]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of glucose transmembrane transport [GO:0010829]; neutrophil degranulation [GO:0043312]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]; regulation of prostaglandin biosynthetic process [GO:0031392]; regulation of retrograde trans-synaptic signaling by endocanabinoid [GO:0099178]; regulation of sensory perception of pain [GO:0051930]; triglyceride catabolic process [GO:0019433]	cell junction [GO:0030054]; cytoplasm [GO:0005737]; extracellular space [GO:0005615]; nucleus [GO:0005634]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202]	azurophil granule lumen [GO:0035578]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]	fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; retinoic acid binding [GO:0001972]	fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; retinoic acid binding [GO:0001972]
d4azua__d1ylbb___1		Viridiplantae	Proteobacteria	Streptophyta	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	chloroplast thylakoid membrane [GO:0009535]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	chloroplast thylakoid membrane [GO:0009535]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]
d4azua__d4enza5__1		Metazoa	Proteobacteria	Chordata	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	oxidation-reduction process [GO:0055114]	cellular iron ion homeostasis [GO:0006879]; cellular protein metabolic process [GO:0044267]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; post-translational protein modification [GO:0043687]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]
d4azuc__d2hx8a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	oxidation-reduction process [GO:0055114]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d4b0ba__d3hm0a___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]	thiolester hydrolase activity [GO:0016790]	unsaturated fatty acid biosynthetic process [GO:0006636]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]	thiolester hydrolase activity [GO:0016790]
d4b0hc__d2v9xb___1			Firmicutes	Proteobacteria	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	cytosol [GO:0005829]; dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]; dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	dUMP biosynthetic process [GO:0006226]; dUTP biosynthetic process [GO:0006229]; nucleobase-containing small molecule interconversion [GO:0015949]; response to radiation [GO:0009314]		cytosol [GO:0005829]	dUTP diphosphatase activity [GO:0004170]; magnesium ion binding [GO:0000287]	dCTP deaminase activity [GO:0008829]; nucleotide binding [GO:0000166]
d4b0ib__d4cl6d___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]	unsaturated fatty acid biosynthetic process [GO:0006636]	unsaturated fatty acid biosynthetic process [GO:0006636]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]
d4b0ic__d4b8ua___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]	unsaturated fatty acid biosynthetic process [GO:0006636]	unsaturated fatty acid biosynthetic process [GO:0006636]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]
d4b0id__d1s9ce1__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]; alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	unsaturated fatty acid biosynthetic process [GO:0006636]	alpha-linolenic acid metabolic process [GO:0036109]; androgen metabolic process [GO:0008209]; bile acid biosynthetic process [GO:0006699]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; protein targeting to peroxisome [GO:0006625]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; membrane [GO:0016020]; peroxisomal matrix [GO:0005782]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]	17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO:0044594]; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [GO:0033989]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; isomerase activity [GO:0016853]; long-chain-enoyl-CoA hydratase activity [GO:0016508]; protein homodimerization activity [GO:0042803]
d4b0jl__d4b0id___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]	unsaturated fatty acid biosynthetic process [GO:0006636]	unsaturated fatty acid biosynthetic process [GO:0006636]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]
d4b0jo__d2xfla___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]		unsaturated fatty acid biosynthetic process [GO:0006636]		cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]	
d4b0jp__d3azam___1			Proteobacteria	Apicomplexa	cytoplasm [GO:0005737]; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]; unsaturated fatty acid biosynthetic process [GO:0006636]	hydro-lyase activity [GO:0016836]; fatty acid biosynthetic process [GO:0006633]	unsaturated fatty acid biosynthetic process [GO:0006636]	fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]		(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [GO:0008659]; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity [GO:0008693]; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity [GO:0047451]; trans-2-decenoyl-acyl-carrier-protein isomerase activity [GO:0034017]	hydro-lyase activity [GO:0016836]
d4b0na2_d1fj4d2__1				Proteobacteria	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d4b1yb2_d3fgua2__1	Metazoa	Metazoa	Chordata	Chordata	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]; calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	calcium ion import [GO:0070509]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; NADP metabolic process [GO:0006739]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; regulation of glycolytic process [GO:0006110]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	cell [GO:0005623]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; mannokinase activity [GO:0019158]
d4b2ba__d2g00a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]
d4b2bc__d4yogb___1	Metazoa		Chordata		extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]; induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	digestion [GO:0007586]; proteolysis [GO:0006508]	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host NF-kappaB transcription factor activity [GO:0039644]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; transcription, DNA-templated [GO:0006351]; viral protein processing [GO:0019082]; viral RNA genome replication [GO:0039694]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	host cell endoplasmic reticulum-Golgi intermediate compartment [GO:0044172]; host cell membrane [GO:0033644]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; DNA helicase activity [GO:0003678]; endonuclease activity [GO:0004519]; exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896]; methyltransferase activity [GO:0008168]; omega peptidase activity [GO:0008242]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; zinc ion binding [GO:0008270]
d4b2ob__d5jpea1__1		Fungi	Firmicutes	Ascomycota	cytoplasm [GO:0005737]; 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]	cofactor binding [GO:0048037]; magnesium-dependent protein serine/threonine phosphatase activity [GO:0004724]; metal ion binding [GO:0046872]			cytoplasm [GO:0005737]		2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]	cofactor binding [GO:0048037]; magnesium-dependent protein serine/threonine phosphatase activity [GO:0004724]; metal ion binding [GO:0046872]
d4b2od__d3hvqa___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]; cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]; beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]		beta-catenin destruction complex disassembly [GO:1904886]; branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle [GO:0007049]; cell division [GO:0051301]; circadian regulation of gene expression [GO:0032922]; dephosphorylation [GO:0016311]; entrainment of circadian clock by photoperiod [GO:0043153]; glycogen metabolic process [GO:0005977]; lung development [GO:0030324]; negative regulation of protein binding [GO:0032091]; peptidyl-serine dephosphorylation [GO:0070262]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein dephosphorylation [GO:0006470]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981]; regulation of translational initiation by eIF2 alpha dephosphorylation [GO:0036496]; response to lead ion [GO:0010288]; viral process [GO:0016032]	cytoplasm [GO:0005737]	cell-cell adherens junction [GO:0005913]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; glycogen granule [GO:0042587]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; protein phosphatase type 1 complex [GO:0000164]; PTW/PP1 phosphatase complex [GO:0072357]	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [GO:0008663]; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [GO:0004113]; metal ion binding [GO:0046872]	cadherin binding involved in cell-cell adhesion [GO:0098641]; metal ion binding [GO:0046872]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; protein phosphatase 1 binding [GO:0008157]; protein serine/threonine phosphatase activity [GO:0004722]; ribonucleoprotein complex binding [GO:0043021]
d4b2xd__d1fr8b___1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d4b3ed__d1eqwa___1	Metazoa		Chordata	Proteobacteria	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]; activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; superoxide dismutase activity [GO:0004784]; removal of superoxide radicals [GO:0019430]	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; cellular response to ATP [GO:0071318]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to potassium ion [GO:0035865]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; interleukin-12-mediated signaling pathway [GO:0035722]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; placenta development [GO:0001890]; platelet degranulation [GO:0002576]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of phagocytosis [GO:0050766]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein kinase activity [GO:0045859]; regulation of T cell differentiation in thymus [GO:0033081]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to amphetamine [GO:0001975]; response to antipsychotic drug [GO:0097332]; response to axon injury [GO:0048678]; response to carbon monoxide [GO:0034465]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; thymus development [GO:0048538]; transmission of nerve impulse [GO:0019226]	removal of superoxide radicals [GO:0019430]	axon cytoplasm [GO:1904115]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite cytoplasm [GO:0032839]; dense core granule [GO:0031045]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; peroxisome [GO:0005777]; protein-containing complex [GO:0032991]	periplasmic space [GO:0042597]	chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein phosphatase 2B binding [GO:0030346]; Rac GTPase binding [GO:0048365]; superoxide dismutase activity [GO:0004784]; zinc ion binding [GO:0008270]	copper ion binding [GO:0005507]; identical protein binding [GO:0042802]; superoxide dismutase activity [GO:0004784]
d4b3ka__d1jz0d5__1			Firmicutes		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	
d4b3kc__d1xgza2__1		Metazoa	Firmicutes	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d4b3kd__d2a3ha___1			Firmicutes	Firmicutes	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; cellulase activity [GO:0008810]
d4b3kd__d3t2pc3__1			Firmicutes	Proteobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d4b3ke__d5i79a1__1		Fungi	Firmicutes	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulase activity [GO:0008810]
d4b3kf__d1jz5b5__1			Firmicutes	Proteobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase complex [GO:0009341]; alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; lactose catabolic process [GO:0005990]	carbohydrate metabolic process [GO:0005975]	lactose catabolic process [GO:0005990]		beta-galactosidase complex [GO:0009341]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alkali metal ion binding [GO:0031420]; beta-galactosidase activity [GO:0004565]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]
d4b3kf__d3ogva1__1		Fungi	Firmicutes	Ascomycota	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	beta-galactosidase activity [GO:0004565]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	beta-galactosidase activity [GO:0004565]
d4b3la__d1x1na1__1		Viridiplantae	Firmicutes	Streptophyta	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	amyloplast [GO:0009501]; chloroplast [GO:0009507]; 4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]	carbohydrate metabolic process [GO:0005975]			amyloplast [GO:0009501]; chloroplast [GO:0009507]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	4-alpha-glucanotransferase activity [GO:0004134]; beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]
d4b3lb__d1osea2__1		Metazoa	Firmicutes	Chordata	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]; alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]; carbohydrate catabolic process [GO:0016052]	carbohydrate metabolic process [GO:0005975]	carbohydrate catabolic process [GO:0016052]		extracellular space [GO:0005615]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	alpha-amylase activity [GO:0004556]; alpha-amylase activity (releasing maltohexaose) [GO:0103025]; calcium ion binding [GO:0005509]; chloride ion binding [GO:0031404]
d4b3lf__d2pwea1__1			Firmicutes	Proteobacteria	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; carbohydrate metabolic process [GO:0005975]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d4b3ua1_d1vzub___1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]		Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d4b3ub__d5m7aa1__1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]		extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]
d4b41b__d4s1dd1__1												
d4b42a__d5nrea___1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein galactosylation at cell surface [GO:0033580]		Golgi apparatus [GO:0005794]; Golgi cisterna [GO:0031985]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; N-acetyllactosaminide 3-alpha-galactosyltransferase activity [GO:0047276]; transferase activity, transferring glycosyl groups [GO:0016757]
d4b42c__d1pzta___1		Metazoa	Proteobacteria	Chordata	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]; alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]; acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	acute inflammatory response [GO:0002526]; angiogenesis involved in wound healing [GO:0060055]; binding of sperm to zona pellucida [GO:0007339]; cell adhesion [GO:0007155]; development of secondary sexual characteristics [GO:0045136]; epithelial cell development [GO:0002064]; extracellular matrix organization [GO:0030198]; galactose metabolic process [GO:0006012]; lactose biosynthetic process [GO:0005989]; leukocyte migration [GO:0050900]; negative regulation of cell population proliferation [GO:0008285]; oligosaccharide biosynthetic process [GO:0009312]; penetration of zona pellucida [GO:0007341]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; protein galactosylation [GO:0042125]; protein homooligomerization [GO:0051260]; protein N-linked glycosylation [GO:0006487]; regulation of acrosome reaction [GO:0060046]		basolateral plasma membrane [GO:0016323]; brush border membrane [GO:0031526]; desmosome [GO:0030057]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; filopodium [GO:0030175]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi trans cisterna [GO:0000138]; integral component of membrane [GO:0016021]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	alpha-tubulin binding [GO:0043014]; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [GO:0003831]; beta-tubulin binding [GO:0048487]; lactose synthase activity [GO:0004461]; manganese ion binding [GO:0030145]; N-acetyllactosamine synthase activity [GO:0003945]; protein homodimerization activity [GO:0042803]; UDP-galactosyltransferase activity [GO:0035250]
d4b49a__d1g06a___1	Metazoa		Chordata		cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]; catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	host cell cytoplasm [GO:0030430]; lysozyme activity [GO:0003796]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	catabolism by organism of cell wall peptidoglycan in other organism [GO:0051672]; cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; killing of cells of other organism [GO:0031640]	cell wall macromolecule catabolic process [GO:0016998]; cytolysis [GO:0019835]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]	host cell cytoplasm [GO:0030430]	beta-N-acetylglucosaminidase activity [GO:0016231]; identical protein binding [GO:0042802]; lysozyme activity [GO:0003796]	lysozyme activity [GO:0003796]
d4b4kb__d4ycca___1			Firmicutes	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d4b4ke__d3orsb1__1			Firmicutes	Firmicutes	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d4b4kf__d4zmbb___1			Firmicutes	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d4b4kg__d2fwbb___1			Firmicutes	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d4b4kh__d2fwab___1			Firmicutes	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d4b4ki__d4zc8a___1			Firmicutes	Proteobacteria	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]; 'de novo' IMP biosynthetic process [GO:0006189]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; 'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]	'de novo' IMP biosynthetic process [GO:0006189]			5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]; lyase activity [GO:0016829]	5-(carboxyamino)imidazole ribonucleotide mutase activity [GO:0034023]
d4b4md__d1hv9a2__1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cytosol [GO:0005829]; glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]; cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]		cytosol [GO:0005829]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	glucosamine-1-phosphate N-acetyltransferase activity [GO:0019134]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; UDP-N-acetylglucosamine diphosphorylase activity [GO:0003977]
d4b4ua1_d3aogb1__1			Proteobacteria	Deinococcus-Thermus	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; nucleotide binding [GO:0000166]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cellular amino acid metabolic process [GO:0006520]			methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; nucleotide binding [GO:0000166]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d4b4wa1_d2aw5c1__1		Metazoa	Proteobacteria	Chordata	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; nucleotide binding [GO:0000166]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	cytosol [GO:0005829]; mitochondrion [GO:0005739]; ADP binding [GO:0043531]; electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; manganese ion binding [GO:0030145]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxaloacetate decarboxylase activity [GO:0008948]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; nucleotide biosynthetic process [GO:0009165]; pyruvate metabolic process [GO:0006090]; regulation of lipid metabolic process [GO:0019216]; regulation of NADP metabolic process [GO:1902031]; response to carbohydrate [GO:0009743]; response to hormone [GO:0009725]	histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; nucleotide biosynthetic process [GO:0009165]; pyruvate metabolic process [GO:0006090]; regulation of lipid metabolic process [GO:0019216]; regulation of NADP metabolic process [GO:1902031]; response to carbohydrate [GO:0009743]; response to hormone [GO:0009725]		cytosol [GO:0005829]; mitochondrion [GO:0005739]	methenyltetrahydrofolate cyclohydrolase activity [GO:0004477]; methylenetetrahydrofolate dehydrogenase (NADP+) activity [GO:0004488]; nucleotide binding [GO:0000166]	ADP binding [GO:0043531]; electron transfer activity [GO:0009055]; malate dehydrogenase (decarboxylating) (NAD+) activity [GO:0004471]; malate dehydrogenase (decarboxylating) (NADP+) activity [GO:0004473]; malic enzyme activity [GO:0004470]; manganese ion binding [GO:0030145]; NAD binding [GO:0051287]; NADP binding [GO:0050661]; oxaloacetate decarboxylase activity [GO:0008948]
d4b50a__d3auvf1__1												
d4b52a__d3t2ie___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]				extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d4b52a__d4nz8a2__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]		angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]		cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metalloaminopeptidase activity [GO:0070006]; peptide binding [GO:0042277]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d4b52b__d1lnde___1			Firmicutes	Firmicutes	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]				extracellular region [GO:0005576]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d4b52b__d2n8ra___1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]		cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d4b55a__d1rlla2__1			Actinobacteria		acetyltransferase activity [GO:0016407]						acetyltransferase activity [GO:0016407]	
d4b5bd__d1mp4b___1			Proteobacteria	Proteobacteria	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; extracellular polysaccharide biosynthetic process [GO:0045226]	dTDP-rhamnose biosynthetic process [GO:0019305]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide core region biosynthetic process [GO:0009244]	extracellular polysaccharide biosynthetic process [GO:0045226]			glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]	glucose-1-phosphate thymidylyltransferase activity [GO:0008879]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d4b5da__d4xk9a1__1	Metazoa	Metazoa	Annelida	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d4b5db__d3wtjc1__1	Metazoa	Metazoa	Annelida	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d4b5dd__d2xz6a___1	Metazoa	Metazoa	Annelida	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d4b5de__d2wnjc1__1	Metazoa	Metazoa	Annelida	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]
d4b5eb__d5ksbf1__1		Metazoa		Chordata		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]		
d4b6cb__d2ygaa___1		Fungi	Actinobacteria	Ascomycota	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; ATPase activity, coupled [GO:0042623]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]; 'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]	'de novo' protein folding [GO:0006458]; box C/D snoRNP assembly [GO:0000492]; cellular response to heat [GO:0034605]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteasome assembly [GO:0043248]; protein folding [GO:0006457]; protein maturation [GO:0051604]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein targeting to mitochondrion [GO:0006626]; regulation of telomere maintenance [GO:0032204]; response to osmotic stress [GO:0006970]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; fungal-type cell wall [GO:0009277]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA negative supercoiling activity [GO:0034335]; metal ion binding [GO:0046872]	ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]; unfolded protein binding [GO:0051082]
d4b6gb1_d1mx9e___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]; formaldehyde catabolic process [GO:0046294]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]; carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]; angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	formaldehyde catabolic process [GO:0046294]	angiotensin maturation [GO:0002003]; cholesterol biosynthetic process [GO:0006695]; cholesterol ester hydrolysis involved in cholesterol transport [GO:0090122]; epithelial cell differentiation [GO:0030855]; lipid catabolic process [GO:0016042]; medium-chain fatty acid metabolic process [GO:0051791]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular space [GO:0005615]	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]	carboxylic ester hydrolase activity [GO:0052689]; methyl indole-3-acetate esterase activity [GO:0080030]; methylumbelliferyl-acetate deacetylase activity [GO:0047374]; sterol esterase activity [GO:0004771]; triglyceride lipase activity [GO:0004806]
d4b6gb1_d6b1ob2__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]; formaldehyde catabolic process [GO:0046294]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	formaldehyde catabolic process [GO:0046294]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cytosol [GO:0005829]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	carboxylic ester hydrolase activity [GO:0052689]; S-formylglutathione hydrolase activity [GO:0018738]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d4b6pa__d5wrfi___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d4b6ra__d5yl5a___1			Proteobacteria	Proteobacteria	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]			3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d4b7da__d4jx1f___1			Actinobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d4b7db__d4zf6a___1			Actinobacteria	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]			cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d4b7ia1_d4jrel1__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; inorganic anion exchanger activity [GO:0005452]; nitrate transmembrane transporter activity [GO:0015112]; nitrite efflux transmembrane transporter activity [GO:0015514]; nitrate assimilation [GO:0042128]; nitrate transport [GO:0015706]; nitrite transport [GO:0015707]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	nitrate assimilation [GO:0042128]; nitrate transport [GO:0015706]; nitrite transport [GO:0015707]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	inorganic anion exchanger activity [GO:0005452]; nitrate transmembrane transporter activity [GO:0015112]; nitrite efflux transmembrane transporter activity [GO:0015514]
d4b7ia2_d2iann1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4b7ja__d1s0ia2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-sialidase activity [GO:0004308]
d4b7ma__d1ms0b2__1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	exo-alpha-sialidase activity [GO:0004308]; pathogenesis [GO:0009405]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	pathogenesis [GO:0009405]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-sialidase activity [GO:0004308]
d4b7pa__d3ttza___1	Metazoa		Chordata	Firmicutes	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]; axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]; DNA topological change [GO:0006265]; DNA-dependent DNA replication [GO:0006261]; response to antibiotic [GO:0046677]	axon extension [GO:0048675]; cellular response to heat [GO:0034605]; central nervous system neuron axonogenesis [GO:0021955]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated protein complex assembly [GO:0051131]; ciliary basal body-plasma membrane docking [GO:0097711]; cofactor metabolic process [GO:0051186]; cytokine-mediated signaling pathway [GO:0019221]; ERBB2 signaling pathway [GO:0038128]; establishment of cell polarity [GO:0030010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G2/M transition of mitotic cell cycle [GO:0000086]; mitochondrial transport [GO:0006839]; neutrophil degranulation [GO:0043312]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein polymerization [GO:0032273]; positive regulation of tau-protein kinase activity [GO:1902949]; positive regulation of telomerase activity [GO:0051973]; protein folding [GO:0006457]; protein insertion into mitochondrial outer membrane [GO:0045040]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular protein localization [GO:1903827]; regulation of cellular response to heat [GO:1900034]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of protein complex assembly [GO:0043254]; regulation of protein ubiquitination [GO:0031396]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; signal transduction [GO:0007165]; telomerase holoenzyme complex assembly [GO:1905323]; telomere maintenance via telomerase [GO:0007004]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]; response to antibiotic [GO:0046677]	axonal growth cone [GO:0044295]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic growth cone [GO:0044294]; endocytic vesicle lumen [GO:0071682]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; lysosomal lumen [GO:0043202]; melanosome [GO:0042470]; membrane [GO:0016020]; myelin sheath [GO:0043209]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule lumen [GO:0034774]	chromosome [GO:0005694]; cytoplasm [GO:0005737]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; disordered domain specific binding [GO:0097718]; DNA polymerase binding [GO:0070182]; GTPase binding [GO:0051020]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; MHC class II protein complex binding [GO:0023026]; nitric-oxide synthase regulator activity [GO:0030235]; nucleotide binding [GO:0000166]; protein folding chaperone [GO:0044183]; protein homodimerization activity [GO:0042803]; protein tyrosine kinase binding [GO:1990782]; RNA binding [GO:0003723]; scaffold protein binding [GO:0097110]; tau protein binding [GO:0048156]; TPR domain binding [GO:0030911]; ubiquitin protein ligase binding [GO:0031625]; unfolded protein binding [GO:0051082]	ATP binding [GO:0005524]; DNA binding [GO:0003677]; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO:0003918]; metal ion binding [GO:0046872]
d4b7qa__d1v0zb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d4b7ra__d1a14n___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d4b7ra__d3beqa___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d4b7rb__d4hzwa1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d4b7rc__d5hukc1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d4b7rd__d4yw4a2__1			Negarnaviricota	Firmicutes	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]		exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d4b7rd__d5kv8a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; metabolic process [GO:0008152]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	metabolic process [GO:0008152]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d4b7sa__d1og2a___1		Metazoa	Actinobacteria	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; (S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cellular amide metabolic process [GO:0043603]; cholesterol metabolic process [GO:0008203]; drug catabolic process [GO:0042737]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; estrogen metabolic process [GO:0008210]; exogenous drug catabolic process [GO:0042738]; icosanoid biosynthetic process [GO:0046456]; long-chain fatty acid biosynthetic process [GO:0042759]; monocarboxylic acid metabolic process [GO:0032787]; monoterpenoid metabolic process [GO:0016098]; omega-hydroxylase P450 pathway [GO:0097267]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; oxidative demethylation [GO:0070989]; steroid metabolic process [GO:0008202]; urea metabolic process [GO:0019627]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(S)-limonene 6-monooxygenase activity [GO:0018675]; (S)-limonene 7-monooxygenase activity [GO:0018676]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; caffeine oxidase activity [GO:0034875]; drug binding [GO:0008144]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity [GO:0016491]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d4b7uc2_d4ojnc2__1		Metazoa	Apicomplexa	Chordata	L-lactate dehydrogenase activity [GO:0004459]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]; cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]; glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	glycolytic process [GO:0006096]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; pyruvate metabolic process [GO:0006090]; response to cAMP [GO:0051591]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; substantia nigra development [GO:0021762]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleus [GO:0005634]	L-lactate dehydrogenase activity [GO:0004459]	cadherin binding [GO:0045296]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d4b7va1_d1xplc2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]	fatty acid biosynthetic process [GO:0006633]	isoprenoid biosynthetic process [GO:0008299]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d4b7va2_d5wx3a1__1		Viridiplantae	Proteobacteria	Streptophyta	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]	fatty acid biosynthetic process [GO:0006633]	biosynthetic process [GO:0009058]	cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d4b7vb2_d1m4sc2__1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]	cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]	fatty acid biosynthetic process [GO:0006633]	poly-hydroxybutyrate biosynthetic process [GO:0042619]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]	acetyl-CoA C-acetyltransferase activity [GO:0003985]
d4b8nb__d3lf5b___1		Metazoa		Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]	endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; perinuclear region of cytoplasm [GO:0048471]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]; bicarbonate transport [GO:0015701]; cell development [GO:0048468]; detection of oxygen [GO:0003032]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; insulin secretion [GO:0030073]; oxidation-reduction process [GO:0055114]; response to antibiotic [GO:0046677]; superoxide metabolic process [GO:0006801]		bicarbonate transport [GO:0015701]; cell development [GO:0048468]; detection of oxygen [GO:0003032]; generation of precursor metabolites and energy [GO:0006091]; glucose homeostasis [GO:0042593]; insulin secretion [GO:0030073]; oxidation-reduction process [GO:0055114]; response to antibiotic [GO:0046677]; superoxide metabolic process [GO:0006801]		endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; perinuclear region of cytoplasm [GO:0048471]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor [GO:0016653]
d4b8nc__d1i5ua___1		Metazoa		Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidation-reduction process [GO:0055114]		oxidation-reduction process [GO:0055114]		cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d4b8nd__d3ks0a___1		Fungi		Ascomycota	heme binding [GO:0020037]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]; heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]; lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]		lactate metabolic process [GO:0006089]; lactate oxidation [GO:0019516]		cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; respirasome [GO:0070469]	heme binding [GO:0020037]; metal ion binding [GO:0046872]	heme binding [GO:0020037]; L-lactate dehydrogenase (cytochrome) activity [GO:0004460]; L-lactate dehydrogenase activity [GO:0004459]; metal ion binding [GO:0046872]
d4b98d__d1gd9a___1			Proteobacteria	Euryarchaeota	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]; beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]	beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	biosynthetic process [GO:0009058]			adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d4b9ba__d2dgme___1			Proteobacteria	Proteobacteria	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]; beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]; glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]	beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	glutamate catabolic process [GO:0006538]; intracellular pH elevation [GO:0051454]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]	glutamate decarboxylase activity [GO:0004351]; pyridoxal phosphate binding [GO:0030170]
d4b9bc__d3gsba___1			Proteobacteria	Cyanobacteria	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]; beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	cytoplasm [GO:0005737]; glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]	beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	chlorophyll biosynthetic process [GO:0015995]; protoporphyrinogen IX biosynthetic process [GO:0006782]		cytoplasm [GO:0005737]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]	glutamate-1-semialdehyde 2,1-aminomutase activity [GO:0042286]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d4b9bc__d5dj9a___1			Proteobacteria	Apicomplexa	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]; beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]; L-proline biosynthetic process [GO:0055129]	beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	L-proline biosynthetic process [GO:0055129]			adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]	ornithine-oxo-acid transaminase activity [GO:0004587]; pyridoxal phosphate binding [GO:0030170]
d4b9bd__d1aiba___1			Proteobacteria	Proteobacteria	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]; beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]; L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]	beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	L-phenylalanine biosynthetic process [GO:0009094]; L-phenylalanine biosynthetic process from chorismate via phenylpyruvate [GO:0033585]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]	identical protein binding [GO:0042802]; L-aspartate:2-oxoglutarate aminotransferase activity [GO:0004069]; L-tyrosine:2-oxoglutarate aminotransferase activity [GO:0004838]; pyridoxal phosphate binding [GO:0030170]
d4b9be__d4rkdh___1			Proteobacteria	Proteobacteria	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]; beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]	beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]			adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]	pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d4b9bg__d3qbob___1			Proteobacteria		adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]; beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]		beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]				adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]	
d4b9fa__d4umsa1__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cell wall organization [GO:0071555]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; hormone activity [GO:0005179]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]; cell wall organization [GO:0071555]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	carbohydrate binding [GO:0030246]; hormone activity [GO:0005179]
d4b9fb__d5gxxa2__1			Firmicutes	Firmicutes	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cell wall organization [GO:0071555]; cellulose catabolic process [GO:0030245]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide catabolic process [GO:0000272]	cellulose catabolic process [GO:0030245]; cell wall organization [GO:0071555]	polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d4ba4b__d5lucn___1		Metazoa	Proteobacteria	Chordata	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]; cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]		cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]		cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]	alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]
d4ba5b__d4kyoc___1		Metazoa	Proteobacteria	Chordata	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]; cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]		cellular nitrogen compound metabolic process [GO:0034641]; glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; protein targeting to peroxisome [GO:0006625]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384]		cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; mitochondrial matrix [GO:0005759]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]	alanine-glyoxylate transaminase activity [GO:0008453]; amino acid binding [GO:0016597]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; pyridoxal phosphate binding [GO:0030170]; serine-pyruvate transaminase activity [GO:0004760]; transaminase activity [GO:0008483]
d4bb5b__d1ee2b2__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	cytosol [GO:0005829]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d4bbnc__d3vh3b___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; nucleus [GO:0005634]; protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of phagophore assembly site membrane [GO:0097632]; membrane [GO:0016020]; mitochondrion [GO:0005739]; phagophore assembly site [GO:0000407]; Atg12 activating enzyme activity [GO:0019778]; Atg8 activating enzyme activity [GO:0019779]; identical protein binding [GO:0042802]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; C-terminal protein lipidation [GO:0006501]; cellular response to nitrogen starvation [GO:0006995]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; piecemeal microautophagy of the nucleus [GO:0034727]; protein modification by small protein conjugation [GO:0032446]	modification-dependent protein catabolic process [GO:0019941]; protein ubiquitination [GO:0016567]	autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; C-terminal protein lipidation [GO:0006501]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; piecemeal microautophagy of the nucleus [GO:0034727]; protein modification by small protein conjugation [GO:0032446]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of phagophore assembly site membrane [GO:0097632]; membrane [GO:0016020]; mitochondrion [GO:0005739]; phagophore assembly site [GO:0000407]	protease binding [GO:0002020]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]	Atg12 activating enzyme activity [GO:0019778]; Atg8 activating enzyme activity [GO:0019779]; identical protein binding [GO:0042802]
d4bboc__d3szig1__1			Proteobacteria	Proteobacteria	biotin binding [GO:0009374]	biotin binding [GO:0009374]					biotin binding [GO:0009374]	biotin binding [GO:0009374]
d4bboc__d4jnjc___1			Proteobacteria		biotin binding [GO:0009374]						biotin binding [GO:0009374]	
d4bbua__d1s67l___1			Proteobacteria	Proteobacteria	identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	cyclic-guanylate-specific phosphodiesterase activity [GO:0071111]; heme binding [GO:0020037]; magnesium ion binding [GO:0000287]; oxygen sensor activity [GO:0019826]; response to oxygen levels [GO:0070482]	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	response to oxygen levels [GO:0070482]			identical protein binding [GO:0042802]; photoreceptor activity [GO:0009881]	cyclic-guanylate-specific phosphodiesterase activity [GO:0071111]; heme binding [GO:0020037]; magnesium ion binding [GO:0000287]; oxygen sensor activity [GO:0019826]
d4bbxa__d2ovva___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytoplasm [GO:0005737]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; cyclic-nucleotide phosphodiesterase activity [GO:0004112]; metal ion binding [GO:0046872]
d4bbxa__d3jwqa___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cytosol [GO:0005829]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	cGMP catabolic process [GO:0046069]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of oocyte development [GO:0060282]; regulation of nitric oxide mediated signal transduction [GO:0010749]; relaxation of cardiac muscle [GO:0055119]; signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]	cytosol [GO:0005829]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cGMP binding [GO:0030553]; metal ion binding [GO:0046872]
d4bbxb__d3v94c___1	Metazoa		Chordata		cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]; cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; regulation of protein kinase A signaling [GO:0010738]	signal transduction [GO:0007165]	cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]		3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; metal ion binding [GO:0046872]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]
d4bbza__d2jida2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d4bbza__d4a16c1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]; acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]; acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	choline metabolic process [GO:0019695]; cocaine metabolic process [GO:0050783]; learning [GO:0007612]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuroblast differentiation [GO:0014016]; response to alkaloid [GO:0043279]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]	acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	blood microparticle [GO:0072562]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; membrane [GO:0016020]; nuclear envelope lumen [GO:0005641]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]	acetylcholinesterase activity [GO:0003990]; amyloid-beta binding [GO:0001540]; catalytic activity [GO:0003824]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]	acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]
d4bc1d__d1wht.1__1	Metazoa	Viridiplantae	Chordata	Streptophyta	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]; acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]; acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	serine-type carboxypeptidase activity [GO:0004185]; proteolysis involved in cellular protein catabolic process [GO:0051603]	acetylcholine catabolic process [GO:0006581]; acetylcholine metabolic process [GO:0008291]; cell adhesion [GO:0007155]; choline metabolic process [GO:0019695]; neuron death [GO:0070997]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of dendrite morphogenesis [GO:0050775]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	proteolysis involved in cellular protein catabolic process [GO:0051603]	anchored component of membrane [GO:0031225]; axon [GO:0030424]; basement membrane [GO:0005604]; cell junction [GO:0030054]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; neuromuscular junction [GO:0031594]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; rough endoplasmic reticulum [GO:0005791]; synapse [GO:0045202]; synaptic cleft [GO:0043083]		acetylcholine binding [GO:0042166]; acetylcholinesterase activity [GO:0003990]; choline binding [GO:0033265]; cholinesterase activity [GO:0004104]; collagen binding [GO:0005518]; hydrolase activity [GO:0016787]; identical protein binding [GO:0042802]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; protein self-association [GO:0043621]; serine hydrolase activity [GO:0017171]	serine-type carboxypeptidase activity [GO:0004185]
d4bcba1_d4re6d1__1	Metazoa		Chordata	Crenarchaeota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cytoplasm [GO:0005737]; serine-type peptidase activity [GO:0008236]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type peptidase activity [GO:0008236]
d4bcda1_d3iuna1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]		endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]
d4bcda2_d1cudb___1	Metazoa	Fungi	Chordata	Ascomycota	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	extracellular region [GO:0005576]; cutinase activity [GO:0050525]			cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	extracellular region [GO:0005576]	endopeptidase activity [GO:0004175]; oligopeptidase activity [GO:0070012]; serine-type endopeptidase activity [GO:0004252]; serine-type exopeptidase activity [GO:0070008]	cutinase activity [GO:0050525]
d4bcea__d4hpha1__1			Deinococcus-Thermus	Proteobacteria	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]			beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d4bceb__d3azrb___1			Deinococcus-Thermus	Thermotogae	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellular glucan metabolic process [GO:0006073]	cellulose catabolic process [GO:0030245]	cellular glucan metabolic process [GO:0006073]		extracellular region [GO:0005576]	beta-glucosidase activity [GO:0008422]; scopolin beta-glucosidase activity [GO:0102483]	hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d4bcgb1_d4nstd2__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cyclin K-CDK12 complex [GO:0002944]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin K-CDK12 complex [GO:0002944]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]
d4bchb1_d4nstb2__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cyclin K-CDK12 complex [GO:0002944]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin K-CDK12 complex [GO:0002944]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]
d4bckb1_d1c9bi2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d4bcob1_d4bcjb2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]; 7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cell population proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; cyclin/CDK positive transcription elongation factor complex [GO:0008024]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasmic ribonucleoprotein granule [GO:0036464]; membrane [GO:0016020]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	7SK snRNA binding [GO:0097322]; ATP binding [GO:0005524]; chromatin binding [GO:0003682]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; DNA binding [GO:0003677]; kinase activity [GO:0016301]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; protein serine/threonine kinase activity [GO:0004674]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription coactivator binding [GO:0001223]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]
d4bcod1_d5acbb1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	cyclin K-CDK12 complex [GO:0002944]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin K-CDK12 complex [GO:0002944]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]
d4bcpb2_d1aisb2__1	Metazoa		Chordata	Euryarchaeota	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-templated transcription, initiation [GO:0006352]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA-templated transcription, initiation [GO:0006352]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]		ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d4bcsb__d2uywd___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d4bdla__d1olaa___1	Metazoa		Chordata	Proteobacteria	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]; peptide transmembrane transporter activity [GO:1904680]; protein transport [GO:0015031]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	protein transport [GO:0015031]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; outer membrane-bounded periplasmic space [GO:0030288]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	peptide transmembrane transporter activity [GO:1904680]
d4bdlb__d3ppra___1	Metazoa		Chordata	Firmicutes	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]; extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]; behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	ATP-binding cassette (ABC) transporter complex [GO:0043190]; transmembrane transporter activity [GO:0022857]; amino acid transport [GO:0006865]	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; inhibitory postsynaptic potential [GO:0060080]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	amino acid transport [GO:0006865]	axon [GO:0030424]; cell [GO:0005623]; cell junction [GO:0030054]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; ionotropic glutamate receptor complex [GO:0008328]; kainate selective glutamate receptor complex [GO:0032983]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; synapse [GO:0045202]; terminal bouton [GO:0043195]	ATP-binding cassette (ABC) transporter complex [GO:0043190]	extracellularly glutamate-gated ion channel activity [GO:0005234]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential [GO:0099507]; PDZ domain binding [GO:0030165]; protein homodimerization activity [GO:0042803]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase binding [GO:0031625]	transmembrane transporter activity [GO:0022857]
d4bele1_d1g9mc1__1	Metazoa	Metazoa	Chordata	Chordata	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine production [GO:0001816]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	adaptive immune response [GO:0002250]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; defense response to Gram-negative bacterium [GO:0050829]; entry into host cell [GO:0030260]; enzyme linked receptor protein signaling pathway [GO:0007167]; fusion of virus membrane with host plasma membrane [GO:0019064]; helper T cell enhancement of adaptive immune response [GO:0035397]; immune response [GO:0006955]; induction by virus of host cell-cell fusion [GO:0006948]; interleukin-15-mediated signaling pathway [GO:0035723]; macrophage differentiation [GO:0030225]; maintenance of protein location in cell [GO:0032507]; membrane organization [GO:0061024]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral entry into host cell [GO:0046598]; regulation of calcium ion transport [GO:0051924]; regulation of defense response to virus by virus [GO:0050690]; regulation of T cell activation [GO:0050863]; response to estradiol [GO:0032355]; response to vitamin D [GO:0033280]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; T cell selection [GO:0045058]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]	cell [GO:0005623]; clathrin-coated vesicle membrane [GO:0030665]; early endosome [GO:0005769]; endoplasmic reticulum lumen [GO:0005788]; endoplasmic reticulum membrane [GO:0005789]; external side of plasma membrane [GO:0009897]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	aspartic-type endopeptidase activity [GO:0004190]	coreceptor activity [GO:0015026]; enzyme binding [GO:0019899]; extracellular matrix structural constituent [GO:0005201]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; interleukin-16 binding [GO:0042011]; interleukin-16 receptor activity [GO:0042012]; MHC class II protein binding [GO:0042289]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein tyrosine kinase binding [GO:1990782]; signaling receptor activity [GO:0038023]; transmembrane signaling receptor activity [GO:0004888]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d4bex1__d5l6wc___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell junction [GO:0005911]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; vesicle [GO:0031982]; actin filament binding [GO:0051015]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; actin filament fragmentation [GO:0030043]; cytoskeleton organization [GO:0007010]; establishment of cell polarity [GO:0030010]; interleukin-12-mediated signaling pathway [GO:0035722]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; neural crest cell migration [GO:0001755]; neural fold formation [GO:0001842]; positive regulation by host of viral process [GO:0044794]; positive regulation of actin filament depolymerization [GO:0030836]; protein phosphorylation [GO:0006468]; regulation of cell morphogenesis [GO:0022604]; regulation of dendritic spine morphogenesis [GO:0061001]; response to amino acid [GO:0043200]; response to virus [GO:0009615]; Rho protein signal transduction [GO:0007266]	cell-cell junction [GO:0005911]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; vesicle [GO:0031982]; actin filament binding [GO:0051015]; signaling receptor binding [GO:0005102]; actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; actin filament fragmentation [GO:0030043]; cytoskeleton organization [GO:0007010]; establishment of cell polarity [GO:0030010]; interleukin-12-mediated signaling pathway [GO:0035722]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; neural crest cell migration [GO:0001755]; neural fold formation [GO:0001842]; positive regulation by host of viral process [GO:0044794]; positive regulation of actin filament depolymerization [GO:0030836]; protein phosphorylation [GO:0006468]; regulation of cell morphogenesis [GO:0022604]; regulation of dendritic spine morphogenesis [GO:0061001]; response to amino acid [GO:0043200]; response to virus [GO:0009615]; Rho protein signal transduction [GO:0007266]	actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; actin filament fragmentation [GO:0030043]; cytoskeleton organization [GO:0007010]; establishment of cell polarity [GO:0030010]; interleukin-12-mediated signaling pathway [GO:0035722]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; neural crest cell migration [GO:0001755]; neural fold formation [GO:0001842]; positive regulation by host of viral process [GO:0044794]; positive regulation of actin filament depolymerization [GO:0030836]; protein phosphorylation [GO:0006468]; regulation of cell morphogenesis [GO:0022604]; regulation of dendritic spine morphogenesis [GO:0061001]; response to amino acid [GO:0043200]; response to virus [GO:0009615]; Rho protein signal transduction [GO:0007266]	actin cytoskeleton organization [GO:0030036]; actin filament depolymerization [GO:0030042]; actin filament fragmentation [GO:0030043]; cytoskeleton organization [GO:0007010]; establishment of cell polarity [GO:0030010]; interleukin-12-mediated signaling pathway [GO:0035722]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; neural crest cell migration [GO:0001755]; neural fold formation [GO:0001842]; positive regulation by host of viral process [GO:0044794]; positive regulation of actin filament depolymerization [GO:0030836]; protein phosphorylation [GO:0006468]; regulation of cell morphogenesis [GO:0022604]; regulation of dendritic spine morphogenesis [GO:0061001]; response to amino acid [GO:0043200]; response to virus [GO:0009615]; Rho protein signal transduction [GO:0007266]	cell-cell junction [GO:0005911]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; vesicle [GO:0031982]	cell-cell junction [GO:0005911]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; membrane [GO:0016020]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; ruffle membrane [GO:0032587]; vesicle [GO:0031982]	actin filament binding [GO:0051015]; signaling receptor binding [GO:0005102]	actin filament binding [GO:0051015]; signaling receptor binding [GO:0005102]
d4bf4a__d3ebsd___1		Metazoa	Actinobacteria	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	coumarin catabolic process [GO:0046226]; coumarin metabolic process [GO:0009804]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]		cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	arachidonic acid epoxygenase activity [GO:0008392]; coumarin 7-hydroxylase activity [GO:0008389]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d4bf4c__d4dufd___1			Actinobacteria	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]			cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d4bf4e__d3kw4a1__1		Metazoa	Actinobacteria	Chordata	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	endoplasmic reticulum membrane [GO:0005789]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]			endoplasmic reticulum membrane [GO:0005789]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d4bf4f__d1zo9b___1			Actinobacteria	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]			cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d4bf4f__d3zkpa___1			Actinobacteria	Actinobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; NADP binding [GO:0050661]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]; macrolide biosynthetic process [GO:0033068]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	macrolide biosynthetic process [GO:0033068]			heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; NADP binding [GO:0050661]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [GO:0016709]
d4bf4i__d1zo4a___1			Actinobacteria	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]			cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d4bf4n__d1pkfa___1			Actinobacteria	Proteobacteria	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; epothilone biosynthetic process [GO:0050814]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	epothilone biosynthetic process [GO:0050814]			heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d4bf4n__d2vrva___1			Actinobacteria		heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]		macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]				heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	
d4bf4o__d4dtzb___1			Actinobacteria	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]			cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d4bf4p__d4hghb___1			Actinobacteria	Firmicutes	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]	macrolide biosynthetic process [GO:0033068]; oxidation-reduction process [GO:0055114]			cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	aromatase activity [GO:0070330]; FMN binding [GO:0010181]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; NADPH-hemoprotein reductase activity [GO:0003958]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]
d4bf7a1_d1hjub___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; cell wall organization [GO:0071555]; pectin catabolic process [GO:0045490]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]; cell wall macromolecule catabolic process [GO:0016998]	cell wall organization [GO:0071555]; pectin catabolic process [GO:0045490]	cell wall macromolecule catabolic process [GO:0016998]	extracellular region [GO:0005576]		arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]	arabinogalactan endo-1,4-beta-galactosidase activity [GO:0031218]; glucosidase activity [GO:0015926]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]
d4bfbd1_d1ktdd1__1	Metazoa	Metazoa	Chordata	Chordata	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]; aspartic-type endopeptidase activity [GO:0004190]; amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]; adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	amyloid-beta metabolic process [GO:0050435]; astrocyte activation [GO:0048143]; glucose homeostasis [GO:0042593]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; peptide hormone processing [GO:0016486]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]	adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]	dense core granule [GO:0031045]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network [GO:0005802]	integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; MHC class II protein complex [GO:0042613]	aspartic-type endopeptidase activity [GO:0004190]	
d4bffa__d1do6a___1			Euryarchaeota	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]					iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4bffb__d4c4uc___1			Euryarchaeota	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]					iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4bffc__d1dqka___1			Euryarchaeota	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]					iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4bffd__d4bfkb___1			Euryarchaeota	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]					iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4bffg__d4c4ba___1			Euryarchaeota	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]					iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4bffj__d4c4un___1			Euryarchaeota	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]					iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4bffk__d1vzia1__1			Euryarchaeota	Proteobacteria	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]			iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4bffn__d4bfjb___1			Euryarchaeota	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]					iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4bfkc__d4bffp___1			Euryarchaeota	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]					iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4bfwb__d2w0sb___1			Actinobacteria		cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]	coenzyme A biosynthetic process [GO:0015937]	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; thymidylate kinase activity [GO:0004798]
d4bfxa__d1ot3a___1		Metazoa	Actinobacteria	Arthropoda	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	coenzyme A biosynthetic process [GO:0015937]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]
d4bfxb__d1xxig2__1			Actinobacteria	Proteobacteria	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; DNA-dependent DNA replication [GO:0006261]	coenzyme A biosynthetic process [GO:0015937]	DNA-dependent DNA replication [GO:0006261]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	DNA polymerase III complex [GO:0009360]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]
d4bfza__d3u3oa___1		Metazoa	Actinobacteria	Chordata	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]; coenzyme A biosynthetic process [GO:0015937]	cytosol [GO:0005829]; aryl sulfotransferase activity [GO:0004062]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]	coenzyme A biosynthetic process [GO:0015937]	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584]; estrogen metabolic process [GO:0008210]; ethanol catabolic process [GO:0006068]; flavonoid metabolic process [GO:0009812]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytosol [GO:0005829]	ATP binding [GO:0005524]; pantothenate kinase activity [GO:0004594]	aryl sulfotransferase activity [GO:0004062]; flavonol 3-sulfotransferase activity [GO:0047894]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]
d4bg4b1_d1qk1d1__1	Metazoa	Metazoa	Arthropoda	Chordata	arginine binding [GO:0034618]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; dTDP metabolic process [GO:0046072]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]; creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]	dTDP metabolic process [GO:0046072]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]	creatine metabolic process [GO:0006600]; phosphocreatine biosynthetic process [GO:0046314]		mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]	arginine binding [GO:0034618]; arginine kinase activity [GO:0004054]; ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]	ATP binding [GO:0005524]; creatine kinase activity [GO:0004111]; kinase activity [GO:0016301]
d4bgef__d1nffa___1			Actinobacteria	Actinobacteria	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	plasma membrane [GO:0005886]; androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; C21-steroid hormone metabolic process [GO:0008207]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	C21-steroid hormone metabolic process [GO:0008207]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	plasma membrane [GO:0005886]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	androstan-3-alpha,17-beta-diol dehydrogenase activity [GO:0047044]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d4bgfe__d2hxzb___1		Metazoa		Chordata		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]		collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d4bgia__d1qsge___1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; membrane [GO:0016020]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]; biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	biotin biosynthetic process [GO:0009102]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; protein homotetramerization [GO:0051289]; response to antibiotic [GO:0046677]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; membrane [GO:0016020]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; identical protein binding [GO:0042802]
d4bgta3_d1obbb1__1				Thermotogae		maltose alpha-glucosidase activity [GO:0032450]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]						maltose alpha-glucosidase activity [GO:0032450]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
d4bgta3_d3ucec___1				Proteobacteria		identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]						identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d4bgtd3_d3uveb___1				Actinobacteria		(+)-trans-carveol dehydrogenase activity [GO:0033702]; nucleotide binding [GO:0000166]						(+)-trans-carveol dehydrogenase activity [GO:0033702]; nucleotide binding [GO:0000166]
d4bgva2_d1smka2__1		Viridiplantae	Euryarchaeota	Streptophyta	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glyoxysome [GO:0009514]; L-malate dehydrogenase activity [GO:0030060]; glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	glyoxylate cycle [GO:0006097]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]		glyoxysome [GO:0009514]	L-malate dehydrogenase activity [GO:0030060]	L-malate dehydrogenase activity [GO:0030060]
d4bgva2_d5es3d2__1		Metazoa	Euryarchaeota	Chordata	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-lactate dehydrogenase activity [GO:0004459]; lactate dehydrogenase activity [GO:0004457]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; lactate metabolic process [GO:0006089]; NAD metabolic process [GO:0019674]; positive regulation of apoptotic process [GO:0043065]; post-embryonic animal organ development [GO:0048569]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]		cytoplasm [GO:0005737]	L-malate dehydrogenase activity [GO:0030060]	identical protein binding [GO:0042802]; kinase binding [GO:0019900]; lactate dehydrogenase activity [GO:0004457]; L-lactate dehydrogenase activity [GO:0004459]; NAD binding [GO:0051287]
d4bgvc1_d1axeb2__1		Metazoa	Euryarchaeota	Chordata	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]		cytosol [GO:0005829]	L-malate dehydrogenase activity [GO:0030060]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d4bgvc2_d2dfdb2__1		Metazoa	Euryarchaeota	Chordata	L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]; aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; gluconeogenesis [GO:0006094]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleus [GO:0005634]	L-malate dehydrogenase activity [GO:0030060]	L-malate dehydrogenase activity [GO:0030060]; malate dehydrogenase (NADP+) activity [GO:0046554]; protein self-association [GO:0043621]; RNA binding [GO:0003723]
d4bgxa__d3ubea___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4bgya__d4we6a1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4bgzc__d4wswe___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4bgze1_d4n60a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d4bh0a__d5xl3b___1			Negarnaviricota		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]		host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		host cell surface receptor binding [GO:0046789]	
d4bh0c__d4wsxq___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4bh0e1_d2wrec1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4bh0e1_d4fp8c___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4bh1e__d5th0c___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4bh2a1_d4ju0e___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4bh4a1_d4wssa1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4bh6d__d3j3ag___1	Fungi		Ascomycota		cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin-protein transferase inhibitor activity [GO:0055105]; cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of ubiquitin protein ligase activity [GO:1904667]		cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of ubiquitin protein ligase activity [GO:1904667]		cytoplasm [GO:0005737]; nucleus [GO:0005634]		ubiquitin-protein transferase inhibitor activity [GO:0055105]	
d4bh6h__d2b5la1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; nucleus [GO:0005634]; ubiquitin-protein transferase inhibitor activity [GO:0055105]; cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of ubiquitin protein ligase activity [GO:1904667]	Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; Cul4A-RING E3 ubiquitin ligase complex [GO:0031464]; Cul4B-RING E3 ubiquitin ligase complex [GO:0031465]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; cullin family protein binding [GO:0097602]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; protein binding, bridging [GO:0030674]; protein-containing complex binding [GO:0044877]; WD40-repeat domain binding [GO:0071987]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; histone H2A monoubiquitination [GO:0035518]; interaction with symbiont [GO:0051702]; negative regulation of apoptotic process [GO:0043066]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral release from host cell [GO:1902188]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of mitotic cell cycle phase transition [GO:1901990]; rhythmic process [GO:0048511]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of ubiquitin protein ligase activity [GO:1904667]	cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; histone H2A monoubiquitination [GO:0035518]; interaction with symbiont [GO:0051702]; negative regulation of apoptotic process [GO:0043066]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral release from host cell [GO:1902188]; post-translational protein modification [GO:0043687]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of mitotic cell cycle phase transition [GO:1901990]; rhythmic process [GO:0048511]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	Cul4A-RING E3 ubiquitin ligase complex [GO:0031464]; Cul4B-RING E3 ubiquitin ligase complex [GO:0031465]; Cul4-RING E3 ubiquitin ligase complex [GO:0080008]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nuclear chromosome, telomeric region [GO:0000784]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	ubiquitin-protein transferase inhibitor activity [GO:0055105]	cullin family protein binding [GO:0097602]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; protein binding, bridging [GO:0030674]; protein-containing complex binding [GO:0044877]; WD40-repeat domain binding [GO:0071987]
d4bhfa2_d5ph3a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]; carnitine biosynthetic process [GO:0045329]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	carnitine biosynthetic process [GO:0045329]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d4bhta2_d1axga2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	cytosol [GO:0005829]; alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]; ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	glutamate biosynthetic process [GO:0006537]	ethanol oxidation [GO:0006069]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	cytosol [GO:0005829]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]	alcohol dehydrogenase activity, zinc-dependent [GO:0004024]; retinol dehydrogenase activity [GO:0004745]; zinc ion binding [GO:0008270]
d4bhtb1_d3k8za1__1			Proteobacteria	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	glutamate dehydrogenase (NAD+) activity [GO:0004352]; cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	glutamate biosynthetic process [GO:0006537]	cellular amino acid metabolic process [GO:0006520]; oxidation-reduction process [GO:0055114]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]	glutamate dehydrogenase (NAD+) activity [GO:0004352]
d4bhtb2_d4z9ff___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]		glutamate biosynthetic process [GO:0006537]		cytoplasm [GO:0005737]; cytosol [GO:0005829]		glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]	
d4bhtc2_d2rbed___1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]; glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	glutamate biosynthetic process [GO:0006537]	glucocorticoid biosynthetic process [GO:0006704]; lung development [GO:0030324]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]	glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [GO:0003845]; steroid binding [GO:0005496]
d4bhtf1_d4fccf1__1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]; glutamate biosynthetic process [GO:0006537]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]; cellular amino acid metabolic process [GO:0006520]	glutamate biosynthetic process [GO:0006537]	cellular amino acid metabolic process [GO:0006520]	cytoplasm [GO:0005737]; cytosol [GO:0005829]		glutamate dehydrogenase (NADP+) activity [GO:0004354]; identical protein binding [GO:0042802]	nucleotide binding [GO:0000166]; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [GO:0016639]
d4bi5a__d8tima___1		Metazoa		Chordata	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]
d4bi5c__d2vffa___1				Apicomplexa	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]		methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]
d4bi5c__d5csrc1__1				Euryarchaeota	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d4bi5d__d1tpvb___1		Metazoa		Chordata	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]
d4bi5d__d3gvgb___1				Actinobacteria	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d4bi5g__d3ta6a___1				Actinobacteria	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d4bi5k__d3pwab___1				Apicomplexa	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]		methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]	identical protein binding [GO:0042802]; triose-phosphate isomerase activity [GO:0004807]
d4bi5k__d4y90d___1				Deinococcus-Thermus	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d4bi5o__d5csra___1				Euryarchaeota	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d4bi5o__d5i3kb___1					cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]; glycosome [GO:0020015]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]; glycosome [GO:0020015]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d4bi5r__d2i9ed1__1		Metazoa		Arthropoda	cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	cytoplasm [GO:0005737]		methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]	triose-phosphate isomerase activity [GO:0004807]
d4bi7a__d2yc8d___1					cytoplasm [GO:0005737]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]		cytoplasm [GO:0005737]		methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]	
d4bifb__d2uyaa___1			Acidobacteria	Firmicutes	metal ion binding [GO:0046872]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]; oxalate decarboxylase activity [GO:0046564]; oxalate metabolic process [GO:0033609]		oxalate metabolic process [GO:0033609]		cytoplasm [GO:0005737]	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]; nutrient reservoir activity [GO:0045735]; oxalate decarboxylase activity [GO:0046564]
d4bifb__d4hmza1__1			Acidobacteria	Actinobacteria	metal ion binding [GO:0046872]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]; antibiotic biosynthetic process [GO:0017000]; carbohydrate metabolic process [GO:0005975]		antibiotic biosynthetic process [GO:0017000]; carbohydrate metabolic process [GO:0005975]			metal ion binding [GO:0046872]	dTDP-4-dehydrorhamnose 3,5-epimerase activity [GO:0008830]
d4biff__d4axob1__1			Acidobacteria	Firmicutes	metal ion binding [GO:0046872]	metal ion binding [GO:0046872]					metal ion binding [GO:0046872]	metal ion binding [GO:0046872]
d4bifg__d2pamb___1			Acidobacteria	Firmicutes	metal ion binding [GO:0046872]	isomerase activity [GO:0016853]					metal ion binding [GO:0046872]	isomerase activity [GO:0016853]
d4bioa__d5a7na___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; 2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; ankyrin repeat binding [GO:0071532]; carboxylic acid binding [GO:0031406]; cofactor binding [GO:0048037]; hypoxia-inducible factor-asparagine oxygenase activity [GO:0102113]; iron ion binding [GO:0005506]; NF-kappaB binding [GO:0051059]; Notch binding [GO:0005112]; oxygen sensor activity [GO:0019826]; peptidyl-asparagine 3-dioxygenase activity [GO:0036140]; peptidyl-histidine dioxygenase activity [GO:0036139]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; oxidation-reduction process [GO:0055114]; peptidyl-asparagine hydroxylation [GO:0042265]; peptidyl-aspartic acid hydroxylation [GO:0042264]; peptidyl-histidine hydroxylation [GO:0036138]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of vasculogenesis [GO:2001214]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; oxidation-reduction process [GO:0055114]; peptidyl-asparagine hydroxylation [GO:0042265]; peptidyl-aspartic acid hydroxylation [GO:0042264]; peptidyl-histidine hydroxylation [GO:0036138]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of vasculogenesis [GO:2001214]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; ankyrin repeat binding [GO:0071532]; carboxylic acid binding [GO:0031406]; cofactor binding [GO:0048037]; hypoxia-inducible factor-asparagine oxygenase activity [GO:0102113]; iron ion binding [GO:0005506]; NF-kappaB binding [GO:0051059]; Notch binding [GO:0005112]; oxygen sensor activity [GO:0019826]; peptidyl-asparagine 3-dioxygenase activity [GO:0036140]; peptidyl-histidine dioxygenase activity [GO:0036139]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d4bisa__d5pjra___1	Metazoa	Metazoa	Chordata	Chordata	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of autophagy [GO:0010507]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; viral process [GO:0016032]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K36 specific) [GO:0051864]; histone demethylase activity (H3-K9 specific) [GO:0032454]; methylated histone binding [GO:0035064]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d4bj0a1_d1uloa___1			Bacteroidetes	Actinobacteria	hydrolase activity, acting on glycosyl bonds [GO:0016798]; metal ion binding [GO:0046872]; xylan catabolic process [GO:0045493]	cellulase activity [GO:0008810]; cellulose catabolic process [GO:0030245]	xylan catabolic process [GO:0045493]	cellulose catabolic process [GO:0030245]			hydrolase activity, acting on glycosyl bonds [GO:0016798]; metal ion binding [GO:0046872]	cellulase activity [GO:0008810]
d4bj3a__d3f74b___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; positive regulation of cell-substrate adhesion [GO:0010811]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	positive regulation of cell-substrate adhesion [GO:0010811]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]		cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]
d4bj3b__d4c2ba___1	Metazoa	Metazoa	Chordata	Chordata	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]; positive regulation of cell-substrate adhesion [GO:0010811]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	positive regulation of cell-substrate adhesion [GO:0010811]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]		chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]
d4bj8k__d2y32c___1	Metazoa		Chordata	Proteobacteria	biotin binding [GO:0009374]	biotin binding [GO:0009374]					biotin binding [GO:0009374]	biotin binding [GO:0009374]
d4bj8n__d1swkb___1	Metazoa		Chordata	Actinobacteria	biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]				extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d4bj8n__d3szic___1	Metazoa		Chordata	Proteobacteria	biotin binding [GO:0009374]	biotin binding [GO:0009374]					biotin binding [GO:0009374]	biotin binding [GO:0009374]
d4bjka1_d5cp4a___1				Proteobacteria	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]; membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	membrane biogenesis [GO:0044091]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	(+)-camphor catabolic process [GO:0019383]	endoplasmic reticulum [GO:0005783]; nuclear envelope [GO:0005635]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; methyltransferase activity [GO:0008168]; sterol 14-demethylase activity [GO:0008398]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d4bjla2_d2pcpc1__1												
d4bjlb1_d3qp3c___1		Metazoa		Chordata		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]		condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]		actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d4bjoa1_d1ptva___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d4bjob1_d5y15a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	phosphatase activity [GO:0016791]; protein tyrosine phosphatase activity [GO:0004725]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; dephosphorylation [GO:0016311]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	dephosphorylation [GO:0016311]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]		cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]	phosphatase activity [GO:0016791]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725]
d4bjxa1_d2d82a2__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein-containing complex assembly [GO:0065003]; protein destabilization [GO:0031648]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d4bk9c__d3eb2c___1				Proteobacteria		lyase activity [GO:0016829]						lyase activity [GO:0016829]
d4bkea1_d2vufa2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]; antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]; cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	cellular protein metabolic process [GO:0044267]; cellular response to starvation [GO:0009267]; high-density lipoprotein particle remodeling [GO:0034375]; maintenance of mitochondrion location [GO:0051659]; negative regulation of apoptotic process [GO:0043066]; negative regulation of programmed cell death [GO:0043069]; negative regulation of protein oligomerization [GO:0032460]; platelet degranulation [GO:0002576]; post-translational protein modification [GO:0043687]; receptor-mediated endocytosis [GO:0006898]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	blood microparticle [GO:0072562]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; nucleus [GO:0005634]; platelet alpha granule lumen [GO:0031093]; protein-containing complex [GO:0032991]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]	antioxidant activity [GO:0016209]; chaperone binding [GO:0051087]; copper ion binding [GO:0005507]; DNA binding [GO:0003677]; drug binding [GO:0008144]; enterobactin binding [GO:1903981]; exogenous protein binding [GO:0140272]; fatty acid binding [GO:0005504]; identical protein binding [GO:0042802]; pyridoxal phosphate binding [GO:0030170]; toxic substance binding [GO:0015643]; zinc ion binding [GO:0008270]
d4bkmb__d4uata___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; glycerol-1-phosphatase activity [GO:0000121]; glycerol-3-phosphatase activity [GO:0043136]; magnesium ion binding [GO:0000287]; nucleotide phosphatase activity, acting on free nucleotides [GO:0098519]; phosphatase activity [GO:0016791]; phosphoglycolate phosphatase activity [GO:0008967]; protein tyrosine phosphatase activity [GO:0004725]; dephosphorylation [GO:0016311]; glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721]; peptidyl-tyrosine dephosphorylation [GO:0035335]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	dephosphorylation [GO:0016311]; glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721]; peptidyl-tyrosine dephosphorylation [GO:0035335]		cytoplasm [GO:0005737]		glycerol-1-phosphatase activity [GO:0000121]; glycerol-3-phosphatase activity [GO:0043136]; magnesium ion binding [GO:0000287]; nucleotide phosphatase activity, acting on free nucleotides [GO:0098519]; phosphatase activity [GO:0016791]; phosphoglycolate phosphatase activity [GO:0008967]; protein tyrosine phosphatase activity [GO:0004725]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d4bkpb1_d2iedc___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d4bkpc1_d1zk3c___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d4bksg__d4auqc1__1	Metazoa	Metazoa	Chordata	Chordata	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]; ubiquitin protein ligase binding [GO:0031625]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	post-translational protein modification [GO:0043687]; protein-containing complex assembly [GO:0065003]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	Cul2-RING ubiquitin ligase complex [GO:0031462]; Cul5-RING ubiquitin ligase complex [GO:0031466]; cytosol [GO:0005829]; elongin complex [GO:0070449]; nucleoplasm [GO:0005654]; VCB complex [GO:0030891]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	ubiquitin protein ligase binding [GO:0031625]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]
d4bl2a2_d1mwub2__1			Firmicutes	Firmicutes	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	penicillin binding [GO:0008658]	penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]
d4bl2a2_d4fsfa1__1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	integral component of plasma membrane [GO:0005887]; penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall organization [GO:0071555]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	response to antibiotic [GO:0046677]	cell wall organization [GO:0071555]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	integral component of membrane [GO:0016021]	integral component of plasma membrane [GO:0005887]	penicillin binding [GO:0008658]	penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]
d4bl2b1_d1dmna___1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	response to antibiotic [GO:0046677]	steroid metabolic process [GO:0008202]	integral component of membrane [GO:0016021]		penicillin binding [GO:0008658]	steroid delta-isomerase activity [GO:0004769]
d4bl2b2_d5m1aa2__1			Firmicutes	Firmicutes	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; transferase activity, transferring glycosyl groups [GO:0016757]; response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	response to antibiotic [GO:0046677]	integral component of membrane [GO:0016021]	integral component of membrane [GO:0016021]	penicillin binding [GO:0008658]	penicillin binding [GO:0008658]; transferase activity, transferring glycosyl groups [GO:0016757]
d4bl3b1_d3wmda___1			Firmicutes	Actinobacteria	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	isomerase activity [GO:0016853]	response to antibiotic [GO:0046677]		integral component of membrane [GO:0016021]		penicillin binding [GO:0008658]	isomerase activity [GO:0016853]
d4bl3b2_d5df8a1__1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	integral component of plasma membrane [GO:0005887]; penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; cell wall organization [GO:0071555]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	response to antibiotic [GO:0046677]	cell wall organization [GO:0071555]; division septum assembly [GO:0000917]; FtsZ-dependent cytokinesis [GO:0043093]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	integral component of membrane [GO:0016021]	integral component of plasma membrane [GO:0005887]	penicillin binding [GO:0008658]	penicillin binding [GO:0008658]; peptidoglycan glycosyltransferase activity [GO:0008955]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]
d4bl5b1_d3vphc1__1	Metazoa		Chordata	Deinococcus-Thermus	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	cytoplasm [GO:0005737]; L-lactate dehydrogenase activity [GO:0004459]; glycolytic process [GO:0006096]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]	coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]	L-lactate dehydrogenase activity [GO:0004459]
d4bl5c1_d1zk1a___1	Metazoa		Chordata	Firmicutes	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]		coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]	metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d4bl5f__d2aq8a___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d4bl5j__d1fdva___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]; estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	estrogen biosynthetic process [GO:0006703]; estrogen metabolic process [GO:0008210]; steroid biosynthetic process [GO:0006694]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]	catalytic activity [GO:0003824]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; estradiol binding [GO:1903924]; NADP+ binding [GO:0070401]; steroid binding [GO:0005496]
d4bl5j__d3rkua1__1	Metazoa	Fungi	Chordata	Ascomycota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	cytoplasm [GO:0005737]; nucleus [GO:0005634]; carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity [GO:0016491]; serine 3-dehydrogenase activity [GO:0031132]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]		cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cytoplasm [GO:0005737]; nucleus [GO:0005634]	coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]	carbonyl reductase (NADPH) activity [GO:0004090]; oxidoreductase activity [GO:0016491]; serine 3-dehydrogenase activity [GO:0031132]
d4bl5k__d2ieba___1	Metazoa		Chordata	Actinobacteria	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]
d4bl5l1_d1euze1__1	Metazoa		Chordata	Euryarchaeota	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]; 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]; cellular amino acid metabolic process [GO:0006520]	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]; T cell mediated cytotoxicity [GO:0001913]	cellular amino acid metabolic process [GO:0006520]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		coenzyme binding [GO:0050662]; electron transfer activity [GO:0009055]; GDP-4-dehydro-D-rhamnose reductase activity [GO:0042356]; GDP-L-fucose synthase activity [GO:0050577]; GDP-mannose 3,5-epimerase activity [GO:0047918]; identical protein binding [GO:0042802]	glutamate dehydrogenase [NAD(P)+] activity [GO:0004353]
d4blia1_d3duib___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]; myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	myoblast differentiation [GO:0045445]; plasma cell differentiation [GO:0002317]; positive regulation of viral entry into host cell [GO:0046598]; T cell costimulation [GO:0031295]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]	carbohydrate binding [GO:0030246]; laminin binding [GO:0043236]
d4blja1_d3wuca___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	carbohydrate binding [GO:0030246]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]		cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]		carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]	carbohydrate binding [GO:0030246]
d4blna__d1bvaa___1	Fungi	Fungi	Basidiomycota	Ascomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d4blua__d3b7pc___1			Proteobacteria	Apicomplexa	cytosol [GO:0005829]; 23S rRNA (adenine(2030)-N(6))-methyltransferase activity [GO:0036307]; RNA binding [GO:0003723]; rRNA (adenine-N6-)-methyltransferase activity [GO:0008988]; carbon utilization [GO:0015976]; rRNA base methylation [GO:0070475]	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	carbon utilization [GO:0015976]; rRNA base methylation [GO:0070475]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	cytosol [GO:0005829]	cytosol [GO:0005829]	23S rRNA (adenine(2030)-N(6))-methyltransferase activity [GO:0036307]; RNA binding [GO:0003723]; rRNA (adenine-N6-)-methyltransferase activity [GO:0008988]	spermidine synthase activity [GO:0004766]
d4blxa__d1h5la___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	extracellular region [GO:0005576]; vacuole [GO:0005773]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d4blya__d2pcba___1	Fungi	Fungi	Basidiomycota	Ascomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	extracellular region [GO:0005576]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d4blzb__d4jqna___1	Fungi	Fungi	Basidiomycota	Ascomycota	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]	integral component of membrane [GO:0016021]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d4bm0a__d5sxqa1__1	Fungi		Basidiomycota	Proteobacteria	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d4bm1a__d1atje___1	Fungi	Viridiplantae	Basidiomycota	Streptophyta	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]		extracellular region [GO:0005576]; vacuole [GO:0005773]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d4bm1a__d3fm4a___1	Fungi	Fungi	Basidiomycota	Basidiomycota	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]; hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]	response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; lignin catabolic process [GO:0046274]; response to oxidative stress [GO:0006979]		extracellular region [GO:0005576]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; reactive-black-5:hydrogen-peroxide oxidoreductase activity [GO:0052750]
d4bm3a__d5cjha2__1	Fungi	Fungi	Basidiomycota	Ascomycota	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]		extracellular region [GO:0005576]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d4bm7a1_d5dhxb1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	host cell cytoplasm [GO:0030430]; host cell nucleolus [GO:0044196]; DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]; mRNA transport [GO:0051028]; viral process [GO:0016032]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	mRNA transport [GO:0051028]; viral process [GO:0016032]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	host cell cytoplasm [GO:0030430]; host cell nucleolus [GO:0044196]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	DNA-binding transcription factor activity [GO:0003700]; RNA binding [GO:0003723]
d4bm7b2_d1yc7a1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d4bm8a1_d1lj7f___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]; carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]; acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; killing of cells of other organism [GO:0031640]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of immunological synapse formation [GO:2000521]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:2001189]; negative regulation of T cell receptor signaling pathway [GO:0050860]; neutrophil chemotaxis [GO:0030593]; neutrophil degranulation [GO:0043312]; positive chemotaxis [GO:0050918]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of myeloid cell differentiation [GO:0045637]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	acute-phase response [GO:0006953]; complement activation, classical pathway [GO:0006958]; defense response to Gram-positive bacterium [GO:0050830]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; opsonization [GO:0008228]; positive regulation of gene expression [GO:0010628]; positive regulation of superoxide anion generation [GO:0032930]; regulation of interleukin-8 secretion [GO:2000482]	cell surface [GO:0009986]; collagen-containing extracellular matrix [GO:0062023]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule membrane [GO:0101003]; immunological synapse [GO:0001772]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; nucleus [GO:0005634]; other organism cell [GO:0044216]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; spliceosomal complex [GO:0005681]	extracellular region [GO:0005576]; extracellular space [GO:0005615]	carbohydrate binding [GO:0030246]; chemoattractant activity [GO:0042056]; IgE binding [GO:0019863]; laminin binding [GO:0043236]; oligosaccharide binding [GO:0070492]; protein phosphatase binding [GO:0019903]; protein phosphatase inhibitor activity [GO:0004864]; RNA binding [GO:0003723]	calcium ion binding [GO:0005509]; choline binding [GO:0033265]; complement component C1q binding [GO:0001849]; identical protein binding [GO:0042802]; low-density lipoprotein particle binding [GO:0030169]; low-density lipoprotein particle receptor binding [GO:0050750]
d4bmba__d5jmce1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]; carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]; cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]; ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]; negative regulation of neurotransmitter secretion [GO:0046929]	cellular response to virus [GO:0098586]; lymphatic endothelial cell migration [GO:1904977]; xenophagy [GO:0098792]	negative regulation of neurotransmitter secretion [GO:0046929]	cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; extracellular space [GO:0005615]; membrane [GO:0016020]	cell wall [GO:0005618]; extracellular region [GO:0005576]; host cell cytoplasmic vesicle [GO:0044161]; host cell cytosol [GO:0044164]; host cell junction [GO:0044156]; host cell presynaptic membrane [GO:0044231]; integral component of membrane [GO:0016021]	carbohydrate binding [GO:0030246]; integrin binding [GO:0005178]	ganglioside GT1b binding [GO:1905576]; metalloendopeptidase activity [GO:0004222]; protein transmembrane transporter activity [GO:0008320]; toxin activity [GO:0090729]; zinc ion binding [GO:0008270]
d4bmoa__d3bvea1__1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity [GO:0016491]
d4bmqa__d5jaca___1		Metazoa	Firmicutes	Chordata	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4bmqb__d2y3qj___1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]
d4bmqb__d4todi___1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4bmrb__d5d8ql___1			Firmicutes	Proteobacteria	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4bmsk__d2nnlf___1		Viridiplantae	Proteobacteria	Streptophyta	nucleotide binding [GO:0000166]	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]; anthocyanin-containing compound biosynthetic process [GO:0009718]		anthocyanin-containing compound biosynthetic process [GO:0009718]			nucleotide binding [GO:0000166]	coenzyme binding [GO:0050662]; dihydrokaempferol 4-reductase activity [GO:0045552]; flavanone 4-reductase activity [GO:0047890]
d4bmtb__d2xkqg___1			Firmicutes	Firmicutes	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d4bmtb__d3wnwh___1		Metazoa	Firmicutes	Chordata	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	integral component of membrane [GO:0016021]; ribonucleoside-diphosphate reductase complex [GO:0005971]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d4bmzb1_d2oece___1			Proteobacteria	Proteobacteria	cytosol [GO:0005829]; 6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	cytoplasm [GO:0005737]; uridine phosphorylase activity [GO:0004850]; nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; menaquinone biosynthetic process [GO:0009234]; nucleoside catabolic process [GO:0009164]	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; UMP salvage [GO:0044206]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	6-amino-6-deoxyfutalosine hydrolase activity [GO:0102246]; adenosylhomocysteine nucleosidase activity [GO:0008782]; methylthioadenosine nucleosidase activity [GO:0008930]	uridine phosphorylase activity [GO:0004850]
d4bn4a__d1u31a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]	cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; NAD binding [GO:0051287]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD(P)+ transhydrogenase activity [GO:0008746]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular oxidant detoxification [GO:0098869]; NADPH regeneration [GO:0006740]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein phosphorylation [GO:0001933]; oxidation-reduction process [GO:0055114]; oxygen homeostasis [GO:0032364]; positive regulation of hydrogen peroxide catabolic process [GO:1903285]; positive regulation of mitochondrial membrane potential [GO:0010918]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593]; response to vitamin [GO:0033273]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]	cell redox homeostasis [GO:0045454]; cellular oxidant detoxification [GO:0098869]; NADPH regeneration [GO:0006740]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein phosphorylation [GO:0001933]; oxidation-reduction process [GO:0055114]; oxygen homeostasis [GO:0032364]; positive regulation of hydrogen peroxide catabolic process [GO:1903285]; positive regulation of mitochondrial membrane potential [GO:0010918]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593]; response to vitamin [GO:0033273]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD(P)+ transhydrogenase activity [GO:0008746]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d4bn4a__d1v5fa1__1	Metazoa		Chordata		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]		enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	
d4bnoa__d5p9wa___1		Metazoa		Chordata		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]		catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]		axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]		catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d4bnqa__d1u5we2__1			Firmicutes	Proteobacteria	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]; nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleotide binding [GO:0000166]; nucleotide metabolic process [GO:0009117]; response to antibiotic [GO:0046677]; thiamine metabolic process [GO:0006772]	nucleotide metabolic process [GO:0009117]; purine nucleoside triphosphate catabolic process [GO:0009146]	nucleotide metabolic process [GO:0009117]; response to antibiotic [GO:0046677]; thiamine metabolic process [GO:0006772]			metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleoside-triphosphate diphosphatase activity [GO:0047429]; nucleotide binding [GO:0000166]	metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; nucleotide binding [GO:0000166]
d4bofa__d8jdwa___1		Metazoa	Firmicutes	Chordata	cytoplasm [GO:0005737]; arginine deiminase activity [GO:0016990]; arginine catabolic process to ornithine [GO:0019547]	extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; amidinotransferase activity [GO:0015067]; glycine amidinotransferase activity [GO:0015068]; creatine biosynthetic process [GO:0006601]; creatine metabolic process [GO:0006600]; learning or memory [GO:0007611]; multicellular organism development [GO:0007275]; muscle atrophy [GO:0014889]; positive regulation of cold-induced thermogenesis [GO:0120162]	arginine catabolic process to ornithine [GO:0019547]	creatine biosynthetic process [GO:0006601]; creatine metabolic process [GO:0006600]; learning or memory [GO:0007611]; multicellular organism development [GO:0007275]; muscle atrophy [GO:0014889]; positive regulation of cold-induced thermogenesis [GO:0120162]	cytoplasm [GO:0005737]	extracellular exosome [GO:0070062]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]	arginine deiminase activity [GO:0016990]	amidinotransferase activity [GO:0015067]; glycine amidinotransferase activity [GO:0015068]
d4bofd__d1g61b___1			Firmicutes	Euryarchaeota	cytoplasm [GO:0005737]; arginine deiminase activity [GO:0016990]; arginine catabolic process to ornithine [GO:0019547]	cytosol [GO:0005829]; nucleolus [GO:0005730]; preribosome, large subunit precursor [GO:0030687]; ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]; translation initiation factor activity [GO:0003743]; assembly of large subunit precursor of preribosome [GO:1902626]; mature ribosome assembly [GO:0042256]; ribosomal subunit export from nucleus [GO:0000054]	arginine catabolic process to ornithine [GO:0019547]	assembly of large subunit precursor of preribosome [GO:1902626]; mature ribosome assembly [GO:0042256]; ribosomal subunit export from nucleus [GO:0000054]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; nucleolus [GO:0005730]; preribosome, large subunit precursor [GO:0030687]	arginine deiminase activity [GO:0016990]	ribosomal large subunit binding [GO:0043023]; ribosome binding [GO:0043022]; translation initiation factor activity [GO:0003743]
d4bofh__d1h70a___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; arginine deiminase activity [GO:0016990]; arginine catabolic process to ornithine [GO:0019547]	amino acid binding [GO:0016597]; dimethylargininase activity [GO:0016403]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]	arginine catabolic process to ornithine [GO:0019547]	arginine metabolic process [GO:0006525]	cytoplasm [GO:0005737]		arginine deiminase activity [GO:0016990]	amino acid binding [GO:0016597]; dimethylargininase activity [GO:0016403]; metal ion binding [GO:0046872]
d4bowb__d1teid___1		Viridiplantae	Bacteroidetes	Streptophyta	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]				glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]	mannose binding [GO:0005537]; metal ion binding [GO:0046872]
d4bozb__d3r3ma___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]; heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of DNA replication [GO:0045740]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	CD95 death-inducing signaling complex [GO:0031265]; cytosol [GO:0005829]; nuclear envelope [GO:0005635]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	heat shock protein binding [GO:0031072]; NF-kappaB binding [GO:0051059]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein kinase regulator activity [GO:0019887]; ubiquitin binding [GO:0043130]; ubiquitin protein ligase binding [GO:0031625]
d4bozc__d2hj8a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]; protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]; activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	activation of MAPK activity [GO:0000187]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cellular protein metabolic process [GO:0044267]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage response, detection of DNA damage [GO:0042769]; endosomal transport [GO:0016197]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; global genome nucleotide-excision repair [GO:0070911]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; interstrand cross-link repair [GO:0036297]; intracellular transport of virus [GO:0075733]; JNK cascade [GO:0007254]; membrane organization [GO:0061024]; modification-dependent protein catabolic process [GO:0019941]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of apoptotic process [GO:0043065]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deubiquitination [GO:0016579]; protein polyubiquitination [GO:0000209]; protein targeting to peroxisome [GO:0006625]; protein ubiquitination [GO:0016567]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; stress-activated MAPK cascade [GO:0051403]; transcription-coupled nucleotide-excision repair [GO:0006283]; transforming growth factor beta receptor signaling pathway [GO:0007179]; translesion synthesis [GO:0019985]; transmembrane transport [GO:0055085]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; viral life cycle [GO:0019058]; virion assembly [GO:0019068]; Wnt signaling pathway [GO:0016055]	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma secretion [GO:0072643]; interleukin-10 secretion [GO:0072608]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of type I interferon production [GO:0032480]; negative regulation of viral genome replication [GO:0045071]; positive regulation of bone mineralization [GO:0030501]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of interferon-gamma production [GO:0032649]; response to type I interferon [GO:0034340]; translesion synthesis [GO:0019985]; type I interferon signaling pathway [GO:0060337]; viral process [GO:0016032]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; endoplasmic reticulum membrane [GO:0005789]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; host cell [GO:0043657]; mitochondrial outer membrane [GO:0005741]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; vesicle [GO:0031982]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	protease binding [GO:0002020]; protein tag [GO:0031386]; RNA binding [GO:0003723]; ubiquitin protein ligase binding [GO:0031625]	integrin binding [GO:0005178]; protein tag [GO:0031386]; ubiquitin protein ligase binding [GO:0031625]
d4bp0b__d5ev8d___1			Proteobacteria	Proteobacteria	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d4bp1b__d5k09m___1		Metazoa	Apicomplexa	Chordata	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]; catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]; catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	catecholamine catabolic process [GO:0042424]; cellular response to phosphate starvation [GO:0016036]; developmental process [GO:0032502]; dopamine catabolic process [GO:0042420]; dopamine metabolic process [GO:0042417]; estrogen metabolic process [GO:0008210]; female pregnancy [GO:0007565]; learning [GO:0007612]; multicellular organismal reproductive process [GO:0048609]; negative regulation of dopamine metabolic process [GO:0045963]; negative regulation of renal sodium excretion [GO:0035814]; negative regulation of smooth muscle cell proliferation [GO:0048662]; neurotransmitter catabolic process [GO:0042135]; positive regulation of homocysteine metabolic process [GO:0050668]; regulation of sensory perception of pain [GO:0051930]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to pain [GO:0048265]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; short-term memory [GO:0007614]	cytosol [GO:0005829]	axon [GO:0030424]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; postsynaptic membrane [GO:0045211]	spermidine synthase activity [GO:0004766]	catechol O-methyltransferase activity [GO:0016206]; L-dopa O-methyltransferase activity [GO:0102084]; magnesium ion binding [GO:0000287]; orcinol O-methyltransferase activity [GO:0102938]
d4bp3a__d1yuba___1			Apicomplexa	Firmicutes	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity [GO:0052910]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]; response to antibiotic [GO:0046677]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	response to antibiotic [GO:0046677]	cytosol [GO:0005829]		spermidine synthase activity [GO:0004766]	23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity [GO:0052910]; RNA binding [GO:0003723]; rRNA (adenine-N6,N6-)-dimethyltransferase activity [GO:0000179]
d4bp3b__d1g6q4___1		Fungi	Apicomplexa	Ascomycota	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	nucleus [GO:0005634]; identical protein binding [GO:0042802]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; folic acid biosynthetic process [GO:0046656]; mRNA export from nucleus [GO:0006406]; negative regulation of DNA-templated transcription, termination [GO:0060567]; peptidyl-arginine methylation [GO:0018216]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	folic acid biosynthetic process [GO:0046656]; mRNA export from nucleus [GO:0006406]; negative regulation of DNA-templated transcription, termination [GO:0060567]; peptidyl-arginine methylation [GO:0018216]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]	cytosol [GO:0005829]	nucleus [GO:0005634]	spermidine synthase activity [GO:0004766]	identical protein binding [GO:0042802]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]
d4bpca2_d2hnqa___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon regeneration [GO:0048681]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of neuron projection development [GO:0010977]; negative regulation of toll-like receptor 9 signaling pathway [GO:0034164]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of postsynaptic density assembly [GO:0099151]; spinal cord development [GO:0021510]; synaptic membrane adhesion [GO:0099560]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	axon [GO:0030424]; cell junction [GO:0030054]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of presynaptic membrane [GO:0099056]; integral component of synaptic vesicle membrane [GO:0030285]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	chondroitin sulfate binding [GO:0035374]; heparan sulfate proteoglycan binding [GO:0043395]; heparin binding [GO:0008201]; phosphoprotein phosphatase activity [GO:0004721]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d4bpvb__d2g8ja___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]; aging [GO:0007568]; brain development [GO:0007420]; cellular response to hydrogen peroxide [GO:0070301]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of vascular permeability [GO:0043117]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; response to angiotensin [GO:1990776]; response to arsenic-containing substance [GO:0046685]; self proteolysis [GO:0097264]	antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	aging [GO:0007568]; brain development [GO:0007420]; cellular response to hydrogen peroxide [GO:0070301]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of vascular permeability [GO:0043117]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; response to angiotensin [GO:1990776]; response to arsenic-containing substance [GO:0046685]; self proteolysis [GO:0097264]	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]	calcium-dependent cysteine-type endopeptidase activity [GO:0004198]; calcium ion binding [GO:0005509]; cytoskeletal protein binding [GO:0008092]; enzyme binding [GO:0019899]
d4bpve__d3ovxa___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d4bpzb1_d3m3ca1__1		Fungi	Bacteroidetes	Basidiomycota	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]	carbohydrate metabolic process [GO:0005975]	apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]			glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]	deoxyribonuclease activity [GO:0004536]; polysaccharide binding [GO:0030247]
d4bpzb1_d4no4c___1		Metazoa	Bacteroidetes	Chordata	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]; apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of viral entry into host cell [GO:0046598]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]	carbohydrate metabolic process [GO:0005975]	apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to organic cyclic compound [GO:0071407]; myoblast differentiation [GO:0045445]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of neuron projection development [GO:0010977]; plasma cell differentiation [GO:0002317]; positive regulation of erythrocyte aggregation [GO:0034120]; positive regulation of viral entry into host cell [GO:0046598]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to isolation stress [GO:0035900]; T cell costimulation [GO:0031295]		cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; lactose binding [GO:0030395]; laminin binding [GO:0043236]; protein homodimerization activity [GO:0042803]
d4bq0b__d1ohyc___1		Metazoa	Proteobacteria	Chordata	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]; beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; (S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate transaminase activity [GO:0003867]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]; behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	beta-alanine biosynthetic process [GO:0019483]; biotin biosynthetic process [GO:0009102]	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]		4-aminobutyrate transaminase complex [GO:0032144]; cytosol [GO:0005829]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; beta-alanine-pyruvate transaminase activity [GO:0016223]; pyridoxal phosphate binding [GO:0030170]	(S)-3-amino-2-methylpropionate transaminase activity [GO:0047298]; 2 iron, 2 sulfur cluster binding [GO:0051537]; 4-aminobutyrate:2-oxoglutarate transaminase activity [GO:0034386]; 4-aminobutyrate transaminase activity [GO:0003867]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; pyridoxal phosphate binding [GO:0030170]; succinate-semialdehyde dehydrogenase binding [GO:0032145]
d4bq1a1_d2slia1__1		Metazoa	Bacteroidetes	Annelida	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	extracellular space [GO:0005615]; anhydrosialidase activity [GO:0033995]; exo-alpha-sialidase activity [GO:0004308]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]		extracellular space [GO:0005615]	glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]	anhydrosialidase activity [GO:0033995]; exo-alpha-sialidase activity [GO:0004308]
d4bqra__d4ibod___1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	oxidoreductase activity [GO:0016491]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]		cell wall [GO:0005618]; plasma membrane [GO:0005886]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	oxidoreductase activity [GO:0016491]
d4bqtb__d3wtle1__1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d4bqte__d1uw6m___1	Metazoa	Metazoa	Mollusca	Mollusca	integral component of membrane [GO:0016021]; extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]; extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]			integral component of membrane [GO:0016021]	cell junction [GO:0030054]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; synapse [GO:0045202]	extracellular ligand-gated ion channel activity [GO:0005230]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; transmembrane signaling receptor activity [GO:0004888]	extracellular ligand-gated ion channel activity [GO:0005230]; transmembrane signaling receptor activity [GO:0004888]
d4bqvb__d5pada___1	Metazoa	Viridiplantae	Chordata	Streptophyta	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]	antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]		cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]	cysteine-type peptidase activity [GO:0008234]; serpin family protein binding [GO:0097655]
d4bqve__d1w6fd___1	Metazoa		Chordata	Actinobacteria	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	arylamine N-acetyltransferase activity [GO:0004060]	antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]		cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]		collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]	arylamine N-acetyltransferase activity [GO:0004060]
d4bqwa__d1os7d___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; 2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; enzyme binding [GO:0019899]; ferrous iron binding [GO:0008198]; L-ascorbic acid binding [GO:0031418]; peptidyl-proline 4-dioxygenase activity [GO:0031545]; peptidyl-proline dioxygenase activity [GO:0031543]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; oxygen homeostasis [GO:0032364]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of angiogenesis [GO:0045765]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; response to nitric oxide [GO:0071731]	cytoplasm [GO:0005737]; L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]; sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]	negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; oxygen homeostasis [GO:0032364]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of angiogenesis [GO:0045765]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; response to nitric oxide [GO:0071731]	sulfur compound catabolic process [GO:0044273]; sulfur compound metabolic process [GO:0006790]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	cytoplasm [GO:0005737]	2-oxoglutarate-dependent dioxygenase activity [GO:0016706]; enzyme binding [GO:0019899]; ferrous iron binding [GO:0008198]; L-ascorbic acid binding [GO:0031418]; peptidyl-proline 4-dioxygenase activity [GO:0031545]; peptidyl-proline dioxygenase activity [GO:0031543]	L-ascorbic acid binding [GO:0031418]; metal ion binding [GO:0046872]; sulfonate dioxygenase activity [GO:0000907]; taurine dioxygenase activity [GO:0000908]
d4br0a1_d1ngga2__1	Metazoa	Metazoa	Chordata	Chordata	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adenosine-diphosphatase activity [GO:0043262]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]; axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	axo-dendritic transport [GO:0008088]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; late endosomal microautophagy [GO:0061738]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; response to unfolded protein [GO:0006986]; RNA splicing [GO:0008380]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	autophagosome [GO:0005776]; axon [GO:0030424]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; lysosome [GO:0005764]; melanosome [GO:0042470]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; presynaptic cytosol [GO:0099523]; Prp19 complex [GO:0000974]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; terminal bouton [GO:0043195]	adenosine-diphosphatase activity [GO:0043262]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]	ATPase activity [GO:0016887]; ATPase activity, coupled [GO:0042623]; ATP binding [GO:0005524]; clathrin-uncoating ATPase activity [GO:1990833]; heat shock protein binding [GO:0031072]; misfolded protein binding [GO:0051787]; protein folding chaperone [GO:0044183]; unfolded protein binding [GO:0051082]
d4br1b__d1mo0b___1	Metazoa	Metazoa	Chordata	Nematoda (roundworms)	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]; methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]; canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cell [GO:0005623]; cytosol [GO:0005829]; myofibril [GO:0030016]; methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]; cell redox homeostasis [GO:0045454]; determination of adult lifespan [GO:0008340]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	canonical glycolysis [GO:0061621]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; methylglyoxal biosynthetic process [GO:0019242]; multicellular organism development [GO:0007275]	cell redox homeostasis [GO:0045454]; determination of adult lifespan [GO:0008340]; gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; nucleus [GO:0005634]	cell [GO:0005623]; cytosol [GO:0005829]; myofibril [GO:0030016]	methylglyoxal synthase activity [GO:0008929]; protein homodimerization activity [GO:0042803]; triose-phosphate isomerase activity [GO:0004807]; ubiquitin protein ligase binding [GO:0031625]	methylglyoxal synthase activity [GO:0008929]; triose-phosphate isomerase activity [GO:0004807]
d4br6a1_d1ar5a1__1	Fungi		Ascomycota	Actinobacteria	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d4br6b1_d2cdyd1__1	Fungi		Ascomycota	Deinococcus-Thermus	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d4br6d1_d1uerb1__1	Fungi		Ascomycota	Bacteroidetes	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d4br6d2_d4gunf2__1	Fungi	Fungi	Ascomycota	Ascomycota	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]					metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]	metal ion binding [GO:0046872]; superoxide dismutase activity [GO:0004784]
d4bs0a__d4go8a1__1	Fungi		Ascomycota	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	xylan catabolic process [GO:0045493]	carbohydrate metabolic process [GO:0005975]			endo-1,4-beta-xylanase activity [GO:0031176]	isomerase activity [GO:0016853]; metal ion binding [GO:0046872]
d4bs0b__d1w3ha___1	Fungi		Ascomycota	Proteobacteria	endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]; xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]	xylan catabolic process [GO:0045493]			endo-1,4-beta-xylanase activity [GO:0031176]	cellulose binding [GO:0030248]; endo-1,4-beta-xylanase activity [GO:0031176]
d4bs6a__d1ukfa1__1	Metazoa		Chordata	Proteobacteria	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	extracellular region [GO:0005576]; host cell membrane [GO:0033644]; membrane [GO:0016020]; cysteine-type endopeptidase activity [GO:0004197]; modulation by symbiont of host defense-related programmed cell death [GO:0034053]; pathogenesis [GO:0009405]	antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	modulation by symbiont of host defense-related programmed cell death [GO:0034053]; pathogenesis [GO:0009405]	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]	extracellular region [GO:0005576]; host cell membrane [GO:0033644]; membrane [GO:0016020]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]	cysteine-type endopeptidase activity [GO:0004197]
d4bs6b__d2ft2b___1	Metazoa	Metazoa	Chordata	Chordata	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]; collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]; adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; bone resorption [GO:0045453]; collagen catabolic process [GO:0030574]; positive regulation of cation channel activity [GO:2001259]; positive regulation of inflammatory response [GO:0050729]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of sensory perception of pain [GO:0051930]; response to acidic pH [GO:0010447]	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen [GO:0048002]; basement membrane disassembly [GO:0034769]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; immune response [GO:0006955]; neutrophil degranulation [GO:0043312]; positive regulation of cation channel activity [GO:2001259]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to acidic pH [GO:0010447]; toll-like receptor signaling pathway [GO:0002224]	cell surface [GO:0009986]; early endosome lumen [GO:0031905]; extracellular space [GO:0005615]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane [GO:0016020]	collagen-containing extracellular matrix [GO:0062023]; endolysosome lumen [GO:0036021]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; ficolin-1-rich granule lumen [GO:1904813]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; lysosome [GO:0005764]; tertiary granule lumen [GO:1904724]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; peptidase activity [GO:0008233]; proteoglycan binding [GO:0043394]	collagen binding [GO:0005518]; cysteine-type endopeptidase activity [GO:0004197]; fibronectin binding [GO:0001968]; laminin binding [GO:0043236]; proteoglycan binding [GO:0043394]
d4bsha__d4wsxc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4bsia__d4wsvc1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4bsva1_d5x2nk1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; G protein-coupled receptor activity [GO:0004930]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	G protein-coupled receptor activity [GO:0004930]
d4bsvb1_d5i1cl1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d4bsvb2_d5da4b___1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d4bswb1_d1u8lb1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d4btea__d3l18b1__1	Metazoa		Chordata	Euryarchaeota	axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; protein-containing complex binding [GO:0044877]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]; activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]	peptidase activity [GO:0008233]	activation of protein kinase B activity [GO:0032148]; adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; DNA repair [GO:0006281]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; glucose homeostasis [GO:0042593]; glutathione deglycation [GO:0036531]; glycolate biosynthetic process [GO:0046295]; glyoxal metabolic process [GO:1903189]; guanine deglycation [GO:0106044]; guanine deglycation, glyoxal removal [GO:0106046]; guanine deglycation, methylglyoxal removal [GO:0106045]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; insulin secretion [GO:0030073]; lactate biosynthetic process [GO:0019249]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal metabolic process [GO:0009438]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of death-inducing signaling complex assembly [GO:1903073]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway [GO:1905259]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; peptidyl-arginine deglycation [GO:0036527]; peptidyl-cysteine deglycation [GO:0036526]; peptidyl-lysine deglycation [GO:0036528]; positive regulation of acute inflammatory response to antigenic stimulus [GO:0002866]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of autophagy of mitochondrion [GO:1903599]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of L-dopa decarboxylase activity [GO:1903200]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tyrosine 3-monooxygenase activity [GO:1903178]; protein deglycation, glyoxal removal [GO:0036529]; protein deglycation, methylglyoxal removal [GO:0036530]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of supramolecular fiber organization [GO:1902903]; single fertilization [GO:0007338]		axon [GO:0030424]; cell [GO:0005623]; cell body [GO:0044297]; cell-cell adherens junction [GO:0005913]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; PML body [GO:0016605]; presynapse [GO:0098793]		androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; copper ion binding [GO:0005507]; cupric ion binding [GO:1903135]; cuprous ion binding [GO:1903136]; cytokine binding [GO:0019955]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; kinase binding [GO:0019900]; L-dopa decarboxylase activator activity [GO:0036478]; mercury ion binding [GO:0045340]; mRNA binding [GO:0003729]; oxidoreductase activity, acting on peroxide as acceptor [GO:0016684]; peptidase activity [GO:0008233]; peroxiredoxin activity [GO:0051920]; protein-containing complex binding [GO:0044877]; protein deglycase activity [GO:0036524]; protein homodimerization activity [GO:0042803]; repressing transcription factor binding [GO:0070491]; scaffold protein binding [GO:0097110]; signaling receptor binding [GO:0005102]; small protein activating enzyme binding [GO:0044388]; superoxide dismutase copper chaperone activity [GO:0016532]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; tyrosine 3-monooxygenase activator activity [GO:0036470]; ubiquitin-like protein conjugating enzyme binding [GO:0044390]; ubiquitin-specific protease binding [GO:1990381]	peptidase activity [GO:0008233]
d4btib__d4fu8a___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	blood coagulation [GO:0007596]; chemotaxis [GO:0006935]; fibrinolysis [GO:0042730]; neutrophil degranulation [GO:0043312]; plasminogen activation [GO:0031639]; positive regulation of cell migration [GO:0030335]; proteolysis [GO:0006508]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell population proliferation [GO:0042127]; regulation of signaling receptor activity [GO:0010469]; regulation of smooth muscle cell-matrix adhesion [GO:2000097]; regulation of smooth muscle cell migration [GO:0014910]; regulation of wound healing [GO:0061041]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; smooth muscle cell migration [GO:0014909]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; tertiary granule membrane [GO:0070821]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]
d4btif__d4d9qb___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4bttf__d1ab9.1__1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	digestion [GO:0007586]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d4btub__d3qzqb___1	Metazoa		Chordata		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	cysteine-type endopeptidase activity [GO:0004197]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]		endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]		calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	cysteine-type endopeptidase activity [GO:0004197]
d4btuf__d1xxfb___1	Metazoa	Metazoa	Chordata	Chordata	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	blood coagulation [GO:0007596]; blood coagulation, extrinsic pathway [GO:0007598]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of cell migration [GO:0030335]; positive regulation of protein kinase B signaling [GO:0051897]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; intrinsic component of external side of plasma membrane [GO:0031233]; plasma membrane [GO:0005886]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	calcium ion binding [GO:0005509]; phospholipid binding [GO:0005543]; serine-type endopeptidase activity [GO:0004252]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]
d4bv6a2_d3dk8a2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; DNA binding [GO:0003677]; FAD binding [GO:0071949]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H [GO:0016651]; protein dimerization activity [GO:0046983]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; chromosome condensation [GO:0030261]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; chromosome condensation [GO:0030261]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; nucleobase-containing small molecule interconversion [GO:0015949]	cytosol [GO:0005829]; mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	cell [GO:0005623]; cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	DNA binding [GO:0003677]; FAD binding [GO:0071949]; NAD(P)H oxidase activity [GO:0016174]; oxidoreductase activity, acting on NAD(P)H [GO:0016651]; protein dimerization activity [GO:0046983]	electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; glutathione-disulfide reductase activity [GO:0004362]; NADP binding [GO:0050661]
d4bvba__d1pnoa1__1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]	aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]		cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NADP binding [GO:0050661]
d4bvhb__d1pt9a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]	cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]; NAD binding [GO:0051287]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD(P)+ transhydrogenase activity [GO:0008746]; NADP binding [GO:0050661]; cell redox homeostasis [GO:0045454]; cellular oxidant detoxification [GO:0098869]; NADPH regeneration [GO:0006740]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein phosphorylation [GO:0001933]; oxidation-reduction process [GO:0055114]; oxygen homeostasis [GO:0032364]; positive regulation of hydrogen peroxide catabolic process [GO:1903285]; positive regulation of mitochondrial membrane potential [GO:0010918]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593]; response to vitamin [GO:0033273]; tricarboxylic acid cycle [GO:0006099]	aerobic respiration [GO:0009060]; aging [GO:0007568]; mitochondrion organization [GO:0007005]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of insulin secretion [GO:0032024]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]	cell redox homeostasis [GO:0045454]; cellular oxidant detoxification [GO:0098869]; NADPH regeneration [GO:0006740]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein phosphorylation [GO:0001933]; oxidation-reduction process [GO:0055114]; oxygen homeostasis [GO:0032364]; positive regulation of hydrogen peroxide catabolic process [GO:1903285]; positive regulation of mitochondrial membrane potential [GO:0010918]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593]; response to vitamin [GO:0033273]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	cell [GO:0005623]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrial respirasome [GO:0005746]; mitochondrion [GO:0005739]	enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; NAD-dependent histone deacetylase activity [GO:0017136]; NAD-dependent protein deacetylase activity [GO:0034979]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]	NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD(P)+ transhydrogenase activity [GO:0008746]; NAD binding [GO:0051287]; NADP binding [GO:0050661]
d4bvma1_d5eeda___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]; cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]; membrane organization [GO:0061024]	extracellular region [GO:0005576]; retinol binding [GO:0019841]	membrane organization [GO:0061024]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]	extracellular region [GO:0005576]	cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]	retinol binding [GO:0019841]
d4bw3a1_d2ydwa___1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]; nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	nucleosome assembly [GO:0006334]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283]; viral process [GO:0016032]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	cytoplasm [GO:0005737]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]	chromatin binding [GO:0003682]; lysine-acetylated histone binding [GO:0070577]
d4bw7a__d1dt7a___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d4bwla1_d1w37b___1			Proteobacteria	Crenarchaeota	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate metabolic process [GO:0005975]	cytosol [GO:0005829]		identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity [GO:0008674]; 2-dehydro-3-deoxy-phosphogluconate aldolase activity [GO:0008675]
d4bwlb__d1qo5j___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose binding [GO:0070061]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]; canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	canonical glycolysis [GO:0061621]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; NADH oxidation [GO:0006116]; positive regulation of ATPase activity [GO:0032781]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	cytosol [GO:0005829]	centriolar satellite [GO:0034451]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule organizing center [GO:0005815]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; fructose-1-phosphate aldolase activity [GO:0061609]; fructose binding [GO:0070061]; fructose-bisphosphate aldolase activity [GO:0004332]; identical protein binding [GO:0042802]
d4bwld1_d5dbte___1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]; carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	cytoplasm [GO:0005737]; deoxyribose-phosphate aldolase activity [GO:0004139]; carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	cytosol [GO:0005829]	cytoplasm [GO:0005737]	identical protein binding [GO:0042802]; N-acetylneuraminate lyase activity [GO:0008747]	deoxyribose-phosphate aldolase activity [GO:0004139]
d4bwqc__d2vctd1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; interleukin-12-mediated signaling pathway [GO:0035722]; xenobiotic metabolic process [GO:0006805]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]		glutathione transferase activity [GO:0004364]
d4bwqe__d1sksb___1	Metazoa		Chordata	Proteobacteria	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]; cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]; viral process [GO:0016032]	cytosol [GO:0005829]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; spliceosomal complex [GO:0005681]; U2-type precatalytic spliceosome [GO:0071005]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U5 snRNP [GO:0005682]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]		oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; protein disulfide oxidoreductase activity [GO:0015035]; protein-disulfide reductase activity [GO:0047134]
d4bwta__d2q9ob3__1		Fungi	Proteobacteria	Ascomycota	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	extraorganismal space [GO:0043245]; copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]; cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]		cellulose catabolic process [GO:0030245]; lignin catabolic process [GO:0046274]	periplasmic space [GO:0042597]	extraorganismal space [GO:0043245]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; hydroquinone:oxygen oxidoreductase activity [GO:0052716]
d4bwtb__d1j9ta1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d4bwua__d2fjsc1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d4bx3a1_d2i55a___1	Metazoa		Chordata		actin cytoskeleton [GO:0015629]; cell-cell junction [GO:0005911]; cleavage furrow [GO:0032154]; contractile ring [GO:0070938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium membrane [GO:0031258]; midbody [GO:0030496]; ruffle membrane [GO:0032587]; growth factor binding [GO:0019838]; heat shock protein binding [GO:0031072]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; phosphoserine phosphatase activity [GO:0004647]; protein homodimerization activity [GO:0042803]; pyridoxal phosphatase activity [GO:0033883]; actin rod assembly [GO:0031247]; cellular response to ATP [GO:0071318]; dephosphorylation [GO:0016311]; positive regulation of actin filament depolymerization [GO:0030836]; protein dephosphorylation [GO:0006470]; pyridoxal phosphate catabolic process [GO:0032361]; regulation of cytokinesis [GO:0032465]; regulation of mitotic nuclear division [GO:0007088]	cytoplasm [GO:0005737]; metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]; GDP-mannose biosynthetic process [GO:0009298]	actin rod assembly [GO:0031247]; cellular response to ATP [GO:0071318]; dephosphorylation [GO:0016311]; positive regulation of actin filament depolymerization [GO:0030836]; protein dephosphorylation [GO:0006470]; pyridoxal phosphate catabolic process [GO:0032361]; regulation of cytokinesis [GO:0032465]; regulation of mitotic nuclear division [GO:0007088]	GDP-mannose biosynthetic process [GO:0009298]	actin cytoskeleton [GO:0015629]; cell-cell junction [GO:0005911]; cleavage furrow [GO:0032154]; contractile ring [GO:0070938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium membrane [GO:0031258]; midbody [GO:0030496]; ruffle membrane [GO:0032587]	cytoplasm [GO:0005737]	growth factor binding [GO:0019838]; heat shock protein binding [GO:0031072]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; phosphoserine phosphatase activity [GO:0004647]; protein homodimerization activity [GO:0042803]; pyridoxal phosphatase activity [GO:0033883]	metal ion binding [GO:0046872]; phosphomannomutase activity [GO:0004615]
d4bx3b__d2r8xp___1	Metazoa		Chordata	Proteobacteria	actin cytoskeleton [GO:0015629]; cell-cell junction [GO:0005911]; cleavage furrow [GO:0032154]; contractile ring [GO:0070938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium membrane [GO:0031258]; midbody [GO:0030496]; ruffle membrane [GO:0032587]; growth factor binding [GO:0019838]; heat shock protein binding [GO:0031072]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; phosphoserine phosphatase activity [GO:0004647]; protein homodimerization activity [GO:0042803]; pyridoxal phosphatase activity [GO:0033883]; actin rod assembly [GO:0031247]; cellular response to ATP [GO:0071318]; dephosphorylation [GO:0016311]; positive regulation of actin filament depolymerization [GO:0030836]; protein dephosphorylation [GO:0006470]; pyridoxal phosphate catabolic process [GO:0032361]; regulation of cytokinesis [GO:0032465]; regulation of mitotic nuclear division [GO:0007088]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	actin rod assembly [GO:0031247]; cellular response to ATP [GO:0071318]; dephosphorylation [GO:0016311]; positive regulation of actin filament depolymerization [GO:0030836]; protein dephosphorylation [GO:0006470]; pyridoxal phosphate catabolic process [GO:0032361]; regulation of cytokinesis [GO:0032465]; regulation of mitotic nuclear division [GO:0007088]	lipopolysaccharide biosynthetic process [GO:0009103]	actin cytoskeleton [GO:0015629]; cell-cell junction [GO:0005911]; cleavage furrow [GO:0032154]; contractile ring [GO:0070938]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium membrane [GO:0031258]; midbody [GO:0030496]; ruffle membrane [GO:0032587]		growth factor binding [GO:0019838]; heat shock protein binding [GO:0031072]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; phosphoprotein phosphatase activity [GO:0004721]; phosphoserine phosphatase activity [GO:0004647]; protein homodimerization activity [GO:0042803]; pyridoxal phosphatase activity [GO:0033883]	3-deoxy-manno-octulosonate-8-phosphatase activity [GO:0019143]; metal ion binding [GO:0046872]
d4bx5b__d3wzpc1__1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d4bx6c__d2uz2d___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d4bx6c__d4gjsa1__1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d4by5b__d1sk6f___1	Metazoa	Metazoa	Arthropoda	Chordata	synaptic vesicle [GO:0008021]; calcium ion binding [GO:0005509]; chemical synaptic transmission [GO:0007268]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; regulation of neurotransmitter secretion [GO:0046928]; vesicle-mediated transport [GO:0016192]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	chemical synaptic transmission [GO:0007268]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; regulation of neurotransmitter secretion [GO:0046928]; vesicle-mediated transport [GO:0016192]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	synaptic vesicle [GO:0008021]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcium ion binding [GO:0005509]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]
d4byaa1_d1osaa___1	Metazoa		Chordata	Ciliophora	protein-containing complex [GO:0032991]; calcium ion binding [GO:0005509]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin binding [GO:0017022]; protein C-terminus binding [GO:0008022]; calcium-mediated signaling [GO:0019722]	calcium ion binding [GO:0005509]; calcium-mediated signaling [GO:0019722]	calcium-mediated signaling [GO:0019722]	calcium-mediated signaling [GO:0019722]	protein-containing complex [GO:0032991]		calcium ion binding [GO:0005509]; CH domain binding [GO:0051401]; disordered domain specific binding [GO:0097718]; myosin binding [GO:0017022]; protein C-terminus binding [GO:0008022]	calcium ion binding [GO:0005509]
d4byfb__d4orab___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	calcineurin complex [GO:0005955]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcolemma [GO:0042383]; calcium ion binding [GO:0005509]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; cyclosporin A binding [GO:0016018]; phosphatase binding [GO:0019902]; protein domain specific binding [GO:0019904]; calcineurin-NFAT signaling cascade [GO:0033173]; Fc-epsilon receptor signaling pathway [GO:0038095]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	calcineurin-NFAT signaling cascade [GO:0033173]; Fc-epsilon receptor signaling pathway [GO:0038095]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	calcineurin complex [GO:0005955]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcolemma [GO:0042383]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; cyclosporin A binding [GO:0016018]; phosphatase binding [GO:0019902]; protein domain specific binding [GO:0019904]
d4byfd__d2m0ra___1	Metazoa	Metazoa	Chordata	Chordata	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]; adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]; calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; G protein-coupled receptor signaling pathway [GO:0007186]; glycogen catabolic process [GO:0005980]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]; calcium ion binding [GO:0005509]; chemokine receptor binding [GO:0042379]; apoptotic process [GO:0006915]; calcium ion homeostasis [GO:0055074]; defense response to bacterium [GO:0042742]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 4 signaling pathway [GO:0034142]	calcium-mediated signaling [GO:0019722]; cofactor metabolic process [GO:0051186]; detection of calcium ion [GO:0005513]; Fc-epsilon receptor signaling pathway [GO:0038095]; glycogen catabolic process [GO:0005980]; G protein-coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; MAPK cascade [GO:0000165]; muscle contraction [GO:0006936]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; platelet degranulation [GO:0002576]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of cytokinesis [GO:0032465]; regulation of heart rate [GO:0002027]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; response to calcium ion [GO:0051592]; substantia nigra development [GO:0021762]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	apoptotic process [GO:0006915]; calcium ion homeostasis [GO:0055074]; defense response to bacterium [GO:0042742]; positive regulation of granulocyte chemotaxis [GO:0071624]; positive regulation of monocyte chemotaxis [GO:0090026]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 4 signaling pathway [GO:0034142]	calcium channel complex [GO:0034704]; catalytic complex [GO:1902494]; cell [GO:0005623]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; spindle microtubule [GO:0005876]; spindle pole [GO:0000922]; vesicle [GO:0031982]	extracellular exosome [GO:0070062]; perinuclear region of cytoplasm [GO:0048471]	adenylate cyclase activator activity [GO:0010856]; adenylate cyclase binding [GO:0008179]; calcium channel inhibitor activity [GO:0019855]; calcium ion binding [GO:0005509]; disordered domain specific binding [GO:0097718]; ion channel binding [GO:0044325]; N-terminal myristoylation domain binding [GO:0031997]; protein domain specific binding [GO:0019904]; protein kinase binding [GO:0019901]; protein phosphatase activator activity [GO:0072542]; protein serine/threonine kinase activator activity [GO:0043539]; titin binding [GO:0031432]	calcium ion binding [GO:0005509]; chemokine receptor binding [GO:0042379]
d4byha1_d4yhil1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d4byha2_d1c12b2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4byhb1_d1zs8d___1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4byya1_d5c8wd___1		Metazoa	Actinobacteria	Chordata	protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]; ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]; cofactor metabolic process [GO:0051186]; negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	cofactor metabolic process [GO:0051186]; negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	protein-DNA complex [GO:0032993]	apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; protein homodimerization activity [GO:0042803]; protein kinase activity [GO:0004672]
d4byyb1_d3e5ua2__1			Actinobacteria	Firmicutes	protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; regulation of transcription, DNA-templated [GO:0006355]	regulation of glyoxylate cycle [GO:2000874]; regulation of transcription, DNA-templated [GO:0006355]	regulation of transcription, DNA-templated [GO:0006355]	protein-DNA complex [GO:0032993]		cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription activator activity [GO:0001216]; DNA-binding transcription repressor activity [GO:0001217]; kinase activity [GO:0016301]; transcription regulatory region sequence-specific DNA binding [GO:0000976]	DNA binding [GO:0003677]
d4bz1l2_d1f6ab1__1		Metazoa		Chordata	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	external side of plasma membrane [GO:0009897]; extracellular region [GO:0005576]; immunoglobulin complex, circulating [GO:0042571]	protein dimerization activity [GO:0046983]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4bz1l2_d3juye1__1					host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]		fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]		host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]		protein dimerization activity [GO:0046983]	
d4bz2a1_d2jhvd2__1		Metazoa		Chordata	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell adhesion [GO:0007162]; positive regulation of axonogenesis [GO:0050772]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]	protein dimerization activity [GO:0046983]	GTPase activator activity [GO:0005096]; Rac GTPase binding [GO:0048365]; Rho GDP-dissociation inhibitor activity [GO:0005094]
d4bz2l1_d4pjgf2__1		Metazoa		Chordata	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; protein dimerization activity [GO:0046983]; fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	fusion of virus membrane with host endosome membrane [GO:0039654]; virion attachment to host cell [GO:0019062]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	protein dimerization activity [GO:0046983]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4bz3b__d4d1ua___1			Proteobacteria	Proteobacteria	metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]		antibiotic catabolic process [GO:0017001]			metal ion binding [GO:0046872]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d4bzpb__d6bcac___1		Metazoa	Actinobacteria	Chordata	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	actin filament [GO:0005884]; cell cortex [GO:0005938]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; cAMP-dependent protein kinase activity [GO:0004691]; MAP-kinase scaffold activity [GO:0005078]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; protein kinase A binding [GO:0051018]; Rho GTPase binding [GO:0017048]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of glucocorticoid mediated signaling pathway [GO:1900169]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056]	hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0086023]; adrenergic receptor signaling pathway [GO:0071875]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; cell growth involved in cardiac muscle cell development [GO:0061049]; G protein-coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; nuclear export [GO:0051168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of glucocorticoid mediated signaling pathway [GO:1900169]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056]		actin filament [GO:0005884]; cell cortex [GO:0005938]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	cAMP-dependent protein kinase activity [GO:0004691]; MAP-kinase scaffold activity [GO:0005078]; metal ion binding [GO:0046872]; molecular adaptor activity [GO:0060090]; protein kinase A binding [GO:0051018]; Rho GTPase binding [GO:0017048]; Rho guanyl-nucleotide exchange factor activity [GO:0005089]
d4bzqa__d6q21c___1		Metazoa	Actinobacteria	Chordata	cytosol [GO:0005829]; plasma membrane [GO:0005886]; sulfate adenylyltransferase complex (ATP) [GO:0009336]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cellular response to oxidative stress [GO:0034599]; cellular response to sulfur starvation [GO:0010438]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; protein C-terminus binding [GO:0008022]; animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cellular response to oxidative stress [GO:0034599]; cellular response to sulfur starvation [GO:0010438]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]	animal organ morphogenesis [GO:0009887]; cell cycle arrest [GO:0007050]; cell surface receptor signaling pathway [GO:0007166]; cellular response to gamma radiation [GO:0071480]; cellular senescence [GO:0090398]; chemotaxis [GO:0006935]; defense response to protozoan [GO:0042832]; endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; intrinsic apoptotic signaling pathway [GO:0097193]; MAPK cascade [GO:0000165]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JNK cascade [GO:0046330]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of ruffle assembly [GO:1900029]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of wound healing [GO:0090303]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; response to isolation stress [GO:0035900]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; sulfate adenylyltransferase complex (ATP) [GO:0009336]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein C-terminus binding [GO:0008022]
d4bzqb__d3fwya___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; plasma membrane [GO:0005886]; sulfate adenylyltransferase complex (ATP) [GO:0009336]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cellular response to oxidative stress [GO:0034599]; cellular response to sulfur starvation [GO:0010438]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on iron-sulfur proteins as donors [GO:0016730]; oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor [GO:0016636]; light-independent bacteriochlorophyll biosynthetic process [GO:0036070]; photosynthesis, dark reaction [GO:0019685]	cellular response to oxidative stress [GO:0034599]; cellular response to sulfur starvation [GO:0010438]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]	light-independent bacteriochlorophyll biosynthetic process [GO:0036070]; photosynthesis, dark reaction [GO:0019685]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; sulfate adenylyltransferase complex (ATP) [GO:0009336]		adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	4 iron, 4 sulfur cluster binding [GO:0051539]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on iron-sulfur proteins as donors [GO:0016730]; oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor [GO:0016636]
d4bzqb__d5cj2f___1		Metazoa	Actinobacteria	Chordata	cytosol [GO:0005829]; plasma membrane [GO:0005886]; sulfate adenylyltransferase complex (ATP) [GO:0009336]; adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; sulfate adenylyltransferase (ATP) activity [GO:0004781]; cellular response to oxidative stress [GO:0034599]; cellular response to sulfur starvation [GO:0010438]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cellular response to oxidative stress [GO:0034599]; cellular response to sulfur starvation [GO:0010438]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]; sulfate assimilation via adenylyl sulfate reduction [GO:0010134]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytosol [GO:0005829]; plasma membrane [GO:0005886]; sulfate adenylyltransferase complex (ATP) [GO:0009336]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	adenylylsulfate kinase activity [GO:0004020]; ATP binding [GO:0005524]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; sulfate adenylyltransferase (ATP) activity [GO:0004781]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d4bzsb__d1os9a1__1	Metazoa	Metazoa	Chordata	Chordata	endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; bradykinin receptor binding [GO:0031711]; carboxypeptidase activity [GO:0004180]; chloride ion binding [GO:0031404]; dipeptidyl-peptidase activity [GO:0008239]; drug binding [GO:0008144]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallodipeptidase activity [GO:0070573]; metallopeptidase activity [GO:0008237]; mitogen-activated protein kinase binding [GO:0051019]; mitogen-activated protein kinase kinase binding [GO:0031434]; peptidyl-dipeptidase activity [GO:0008241]; tripeptidyl-peptidase activity [GO:0008240]; zinc ion binding [GO:0008270]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of blood pressure [GO:0045777]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; posttranscriptional regulation of gene expression [GO:0010608]; proteolysis [GO:0006508]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of blood vessel diameter [GO:0097746]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of blood pressure [GO:0045777]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; posttranscriptional regulation of gene expression [GO:0010608]; proteolysis [GO:0006508]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of blood vessel diameter [GO:0097746]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; spermatogenesis [GO:0007283]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	actin binding [GO:0003779]; bradykinin receptor binding [GO:0031711]; carboxypeptidase activity [GO:0004180]; chloride ion binding [GO:0031404]; dipeptidyl-peptidase activity [GO:0008239]; drug binding [GO:0008144]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallodipeptidase activity [GO:0070573]; metallopeptidase activity [GO:0008237]; mitogen-activated protein kinase binding [GO:0051019]; mitogen-activated protein kinase kinase binding [GO:0031434]; peptidyl-dipeptidase activity [GO:0008241]; tripeptidyl-peptidase activity [GO:0008240]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d4c02b__d5hw7b___1	Metazoa	Fungi	Chordata	Ascomycota	calcium channel complex [GO:0034704]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018]; calcium channel inhibitor activity [GO:0019855]; cyclic nucleotide binding [GO:0030551]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; signaling receptor binding [GO:0005102]; 'de novo' protein folding [GO:0006458]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; chaperone-mediated protein folding [GO:0061077]; insulin secretion [GO:0030073]; ion transmembrane transport [GO:0034220]; negative regulation of heart rate [GO:0010459]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of release of sequestered calcium ion into cytosol [GO:0051280]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neuronal action potential propagation [GO:0019227]; positive regulation of axon regeneration [GO:0048680]; positive regulation of sequestering of calcium ion [GO:0051284]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; release of sequestered calcium ion into cytosol [GO:0051209]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to redox state [GO:0051775]; response to vitamin E [GO:0033197]; smooth muscle contraction [GO:0006939]; T cell proliferation [GO:0042098]	cytoplasm [GO:0005737]; fungal biofilm matrix [GO:0062040]; drug binding [GO:0008144]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; cellular response to drug [GO:0035690]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	'de novo' protein folding [GO:0006458]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; chaperone-mediated protein folding [GO:0061077]; insulin secretion [GO:0030073]; ion transmembrane transport [GO:0034220]; negative regulation of heart rate [GO:0010459]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of release of sequestered calcium ion into cytosol [GO:0051280]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neuronal action potential propagation [GO:0019227]; positive regulation of axon regeneration [GO:0048680]; positive regulation of sequestering of calcium ion [GO:0051284]; protein maturation by protein folding [GO:0022417]; protein peptidyl-prolyl isomerization [GO:0000413]; protein refolding [GO:0042026]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; release of sequestered calcium ion into cytosol [GO:0051209]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to redox state [GO:0051775]; response to vitamin E [GO:0033197]; smooth muscle contraction [GO:0006939]; T cell proliferation [GO:0042098]	cellular response to drug [GO:0035690]; chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	calcium channel complex [GO:0034704]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; sarcoplasmic reticulum membrane [GO:0033017]; Z disc [GO:0030018]	cytoplasm [GO:0005737]; fungal biofilm matrix [GO:0062040]	calcium channel inhibitor activity [GO:0019855]; cyclic nucleotide binding [GO:0030551]; FK506 binding [GO:0005528]; ion channel binding [GO:0044325]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; signaling receptor binding [GO:0005102]	drug binding [GO:0008144]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
d4c09a__d4xuka___1			Firmicutes	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]		periplasmic space [GO:0042597]		beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	hydrolase activity [GO:0016787]; metal ion binding [GO:0046872]
d4c0ra1_d3h03a___1		Metazoa	Firmicutes	Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d4c0rb__d5fhoc___1		Metazoa	Firmicutes	Chordata		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]; AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]; synaptic transmission, glutamatergic [GO:0035249]		AMPA glutamate receptor complex [GO:0032281]; asymmetric synapse [GO:0032279]; cell junction [GO:0030054]; cell surface [GO:0009986]; dendrite [GO:0030425]; dendrite cytoplasm [GO:0032839]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; endoplasmic reticulum membrane [GO:0005789]; glutamatergic synapse [GO:0098978]; growth cone [GO:0030426]; integral component of plasma membrane [GO:0005887]; integral component of postsynaptic density membrane [GO:0099061]; integral component of postsynaptic membrane [GO:0099055]; integral component of presynaptic membrane [GO:0099056]; ionotropic glutamate receptor complex [GO:0008328]; neuronal cell body [GO:0043025]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density membrane [GO:0098839]; postsynaptic membrane [GO:0045211]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle membrane [GO:0030672]; terminal bouton [GO:0043195]		AMPA glutamate receptor activity [GO:0004971]; amyloid-beta binding [GO:0001540]; ATPase binding [GO:0051117]; cytoskeletal protein binding [GO:0008092]; glutamate receptor activity [GO:0008066]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; ionotropic glutamate receptor activity [GO:0004970]; kainate selective glutamate receptor activity [GO:0015277]; PDZ domain binding [GO:0030165]; protein kinase binding [GO:0019901]; signaling receptor activity [GO:0038023]; SNARE binding [GO:0000149]; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential [GO:1904315]
d4c0sa2_d1ijfa1__1	Metazoa	Fungi	Chordata	Ascomycota	nucleus [GO:0005634]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]; guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]; maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]		maintenance of translational fidelity [GO:1990145]; negative regulation of actin filament bundle assembly [GO:0032232]; regulation of translational termination [GO:0006449]; translational elongation [GO:0006414]	nucleus [GO:0005634]	cytosol [GO:0005829]; eukaryotic translation elongation factor 1 complex [GO:0005853]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]	guanyl-nucleotide exchange factor activity [GO:0005085]; translation elongation factor activity [GO:0003746]
d4c1fa__d1a8tb___1			Proteobacteria	Bacteroidetes	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d4c1ga__d3ie2b___1			Proteobacteria	Deinococcus-Thermus	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	cytoplasm [GO:0005737]; endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; rRNA processing [GO:0006364]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	rRNA processing [GO:0006364]	periplasmic space [GO:0042597]	cytoplasm [GO:0005737]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]
d4c1gb__d5a5zc1__1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]; beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]; antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	antibiotic catabolic process [GO:0017001]; response to antibiotic [GO:0046677]	periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]	beta-lactamase activity [GO:0008800]; zinc ion binding [GO:0008270]
d4c1ia__d2r8qa___1	Metazoa		Chordata		cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]; signal transduction [GO:0007165]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]		3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]	3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; metal ion binding [GO:0046872]
d4c1ua__d3sewa1__1				Proteobacteria		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]; carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		carbohydrate transport [GO:0008643]; cell chemotaxis [GO:0060326]; cellular response to DNA damage stimulus [GO:0006974]; detection of maltose stimulus [GO:0034289]; maltodextrin transport [GO:0042956]; maltose transport [GO:0015768]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [GO:0055052]; outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]		carbohydrate transmembrane transporter activity [GO:0015144]; maltose binding [GO:1901982]
d4c20a2_d3a9sa2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	L-fucose catabolic process [GO:0042355]	L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]
d4c20b2_d4r1qd2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	L-fucose catabolic process [GO:0042355]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d4c21a2_d2hxgb1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytosol [GO:0005829]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	L-fucose catabolic process [GO:0042355]	arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d4c21b1_d4r1oe1__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	L-fucose catabolic process [GO:0042355]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d4c22a2_d2hxga1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytosol [GO:0005829]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	L-fucose catabolic process [GO:0042355]	arabinose catabolic process [GO:0019568]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d4c22b1_d1fuid2__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytosol [GO:0005829]; arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	L-fucose catabolic process [GO:0042355]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]
d4c22b1_d4r1pd1__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	L-fucose catabolic process [GO:0042355]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d4c22b2_d1fuie1__1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytosol [GO:0005829]; arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	L-fucose catabolic process [GO:0042355]	D-arabinose catabolic process [GO:0019571]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]	cytosol [GO:0005829]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	arabinose isomerase activity [GO:0008790]; identical protein binding [GO:0042802]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]
d4c22b2_d4r1pe2__1			Firmicutes	Firmicutes	cytoplasm [GO:0005737]; L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]; L-fucose catabolic process [GO:0042355]	cytoplasm [GO:0005737]; L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]; L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	L-fucose catabolic process [GO:0042355]	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	L-fucose isomerase activity [GO:0008736]; manganese ion binding [GO:0030145]	L-arabinose isomerase activity [GO:0008733]; manganese ion binding [GO:0030145]
d4c29b__d1n3ya___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell surface [GO:0009986]; ficolin-1-rich granule membrane [GO:0101003]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule membrane [GO:0030667]; tertiary granule membrane [GO:0070821]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]; animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial tube morphogenesis [GO:1905956]; positive regulation of gene expression [GO:0010628]; positive regulation of myelination [GO:0031643]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; cytokine-mediated signaling pathway [GO:0019221]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; neutrophil degranulation [GO:0043312]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial tube morphogenesis [GO:1905956]; positive regulation of gene expression [GO:0010628]; positive regulation of myelination [GO:0031643]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	cell surface [GO:0009986]; ficolin-1-rich granule membrane [GO:0101003]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; secretory granule membrane [GO:0030667]; tertiary granule membrane [GO:0070821]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]	metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; receptor tyrosine kinase binding [GO:0030971]; signaling receptor activity [GO:0038023]
d4c2bb__d3c09a1__1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]; actin filament binding [GO:0051015]; ATP binding [GO:0005524]; ATPase binding [GO:0051117]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor binding [GO:0048408]; epidermal growth factor-activated receptor activity [GO:0005006]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]; activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; astrocyte activation [GO:0048143]; cell-cell adhesion [GO:0098609]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to cadmium ion [GO:0071276]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; cellular response to reactive oxygen species [GO:0034614]; cerebral cortex cell migration [GO:0021795]; circadian rhythm [GO:0007623]; digestive tract morphogenesis [GO:0048546]; diterpenoid metabolic process [GO:0016101]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; hydrogen peroxide metabolic process [GO:0042743]; learning or memory [GO:0007611]; liver regeneration [GO:0097421]; lung development [GO:0030324]; magnesium ion homeostasis [GO:0010960]; MAPK cascade [GO:0000165]; membrane organization [GO:0061024]; midgut development [GO:0007494]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiocyte differentiation [GO:1905208]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein catabolic process [GO:0042177]; neuron projection morphogenesis [GO:0048812]; ossification [GO:0001503]; ovulation cycle [GO:0042698]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of inflammatory response [GO:0050729]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide mediated signal transduction [GO:0010750]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vasoconstriction [GO:0045907]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of transcription by RNA polymerase II [GO:0006357]; response to calcium ion [GO:0051592]; response to cobalamin [GO:0033590]; response to hydroxyisoflavone [GO:0033594]; response to osmotic stress [GO:0006970]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; tongue development [GO:0043586]; translation [GO:0006412]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cell junction [GO:0030054]; cell surface [GO:0009986]; clathrin-coated vesicle membrane [GO:0030665]; cytoplasm [GO:0005737]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; endosome membrane [GO:0010008]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; membrane raft [GO:0045121]; multivesicular body, internal vesicle lumen [GO:0097489]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; receptor complex [GO:0043235]; Shc-EGFR complex [GO:0070435]; synapse [GO:0045202]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]	actin filament binding [GO:0051015]; ATPase binding [GO:0051117]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; chromatin binding [GO:0003682]; double-stranded DNA binding [GO:0003690]; enzyme binding [GO:0019899]; epidermal growth factor-activated receptor activity [GO:0005006]; epidermal growth factor binding [GO:0048408]; identical protein binding [GO:0042802]; integrin binding [GO:0005178]; MAP kinase kinase kinase activity [GO:0004709]; protein heterodimerization activity [GO:0046982]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; ubiquitin protein ligase binding [GO:0031625]; virus receptor activity [GO:0001618]
d4c2be__d1xuob___1	Metazoa	Metazoa	Chordata	Chordata	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]; chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]; cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; extracellular matrix organization [GO:0030198]; hemostasis [GO:0007599]; platelet activation [GO:0030168]; platelet degranulation [GO:0002576]; protein homooligomerization [GO:0051260]; response to wounding [GO:0009611]	cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; memory T cell extravasation [GO:0035683]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; receptor clustering [GO:0043113]; regulation of immune response [GO:0050776]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; platelet alpha granule [GO:0031091]; platelet alpha granule lumen [GO:0031093]; Weibel-Palade body [GO:0033093]	cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integrin alphaL-beta2 complex [GO:0034687]; integrin complex [GO:0008305]; membrane [GO:0016020]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579]	chaperone binding [GO:0051087]; collagen binding [GO:0005518]; identical protein binding [GO:0042802]; immunoglobulin binding [GO:0019865]; integrin binding [GO:0005178]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; protein N-terminus binding [GO:0047485]	cell adhesion molecule binding [GO:0050839]; ICAM-3 receptor activity [GO:0030369]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]
d4c2mg1_d2c35h2__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; RNA polymerase II, core complex [GO:0005665]; DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; translation initiation factor binding [GO:0031369]; 7-methylguanosine mRNA capping [GO:0006370]; apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral transcription [GO:0050434]; regulation of gene silencing by miRNA [GO:0060964]; RNA metabolic process [GO:0016070]; snRNA transcription by RNA polymerase II [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription, DNA-templated [GO:0006351]; transcription-coupled nucleotide-excision repair [GO:0006283]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]	7-methylguanosine mRNA capping [GO:0006370]; apoptotic process [GO:0006915]; fibroblast growth factor receptor signaling pathway [GO:0008543]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral transcription [GO:0050434]; regulation of gene silencing by miRNA [GO:0060964]; RNA metabolic process [GO:0016070]; snRNA transcription by RNA polymerase II [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; transcription by RNA polymerase II [GO:0006366]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription initiation from RNA polymerase II promoter [GO:0006367]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	nucleoplasm [GO:0005654]; nucleus [GO:0005634]; P-body [GO:0000932]; RNA polymerase II, core complex [GO:0005665]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]	DNA-directed 5'-3' RNA polymerase activity [GO:0003899]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; translation initiation factor binding [GO:0031369]
d4c2oa__d4tmne___1	Metazoa		Chordata	Firmicutes	endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; bradykinin receptor binding [GO:0031711]; carboxypeptidase activity [GO:0004180]; chloride ion binding [GO:0031404]; dipeptidyl-peptidase activity [GO:0008239]; drug binding [GO:0008144]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallodipeptidase activity [GO:0070573]; metallopeptidase activity [GO:0008237]; mitogen-activated protein kinase binding [GO:0051019]; mitogen-activated protein kinase kinase binding [GO:0031434]; peptidyl-dipeptidase activity [GO:0008241]; tripeptidyl-peptidase activity [GO:0008240]; zinc ion binding [GO:0008270]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of blood pressure [GO:0045777]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; posttranscriptional regulation of gene expression [GO:0010608]; proteolysis [GO:0006508]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of blood vessel diameter [GO:0097746]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; spermatogenesis [GO:0007283]	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of blood pressure [GO:0045777]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; posttranscriptional regulation of gene expression [GO:0010608]; proteolysis [GO:0006508]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of blood vessel diameter [GO:0097746]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; spermatogenesis [GO:0007283]		endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	actin binding [GO:0003779]; bradykinin receptor binding [GO:0031711]; carboxypeptidase activity [GO:0004180]; chloride ion binding [GO:0031404]; dipeptidyl-peptidase activity [GO:0008239]; drug binding [GO:0008144]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallodipeptidase activity [GO:0070573]; metallopeptidase activity [GO:0008237]; mitogen-activated protein kinase binding [GO:0051019]; mitogen-activated protein kinase kinase binding [GO:0031434]; peptidyl-dipeptidase activity [GO:0008241]; tripeptidyl-peptidase activity [GO:0008240]; zinc ion binding [GO:0008270]	metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]
d4c2qa__d1k9xd___1	Metazoa		Chordata	Euryarchaeota	endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; bradykinin receptor binding [GO:0031711]; carboxypeptidase activity [GO:0004180]; chloride ion binding [GO:0031404]; dipeptidyl-peptidase activity [GO:0008239]; drug binding [GO:0008144]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallodipeptidase activity [GO:0070573]; metallopeptidase activity [GO:0008237]; mitogen-activated protein kinase binding [GO:0051019]; mitogen-activated protein kinase kinase binding [GO:0031434]; peptidyl-dipeptidase activity [GO:0008241]; tripeptidyl-peptidase activity [GO:0008240]; zinc ion binding [GO:0008270]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of blood pressure [GO:0045777]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; posttranscriptional regulation of gene expression [GO:0010608]; proteolysis [GO:0006508]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of blood vessel diameter [GO:0097746]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; spermatogenesis [GO:0007283]	cobalt ion binding [GO:0050897]; metallocarboxypeptidase activity [GO:0004181]; proteolysis [GO:0006508]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of blood pressure [GO:0045777]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; posttranscriptional regulation of gene expression [GO:0010608]; proteolysis [GO:0006508]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of blood vessel diameter [GO:0097746]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; spermatogenesis [GO:0007283]	proteolysis [GO:0006508]	endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; plasma membrane [GO:0005886]		actin binding [GO:0003779]; bradykinin receptor binding [GO:0031711]; carboxypeptidase activity [GO:0004180]; chloride ion binding [GO:0031404]; dipeptidyl-peptidase activity [GO:0008239]; drug binding [GO:0008144]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallodipeptidase activity [GO:0070573]; metallopeptidase activity [GO:0008237]; mitogen-activated protein kinase binding [GO:0051019]; mitogen-activated protein kinase kinase binding [GO:0031434]; peptidyl-dipeptidase activity [GO:0008241]; tripeptidyl-peptidase activity [GO:0008240]; zinc ion binding [GO:0008270]	cobalt ion binding [GO:0050897]; metallocarboxypeptidase activity [GO:0004181]
d4c2sa1_d2jcfa___1	Metazoa		Chordata		extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]; antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]; carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]		carbohydrate metabolic process [GO:0005975]; lipid glycosylation [GO:0030259]; protein glycosylation [GO:0006486]		extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; integral component of membrane [GO:0016021]; vesicle [GO:0031982]		antigen binding [GO:0003823]; fucosylgalactoside 3-alpha-galactosyltransferase activity [GO:0004381]; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity [GO:0004380]; manganese ion binding [GO:0030145]; nucleotide binding [GO:0000166]; transferase activity, transferring glycosyl groups [GO:0016757]	
d4c2xa1_d4c2zb2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; host cell [GO:0043657]; plasma membrane [GO:0005886]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; intracellular transport of virus [GO:0075733]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]; cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	intracellular transport of virus [GO:0075733]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; host cell [GO:0043657]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]
d4c2xa1_d4koua___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; host cell [GO:0043657]; plasma membrane [GO:0005886]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; intracellular transport of virus [GO:0075733]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]	intracellular transport of virus [GO:0075733]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; regulation of rhodopsin mediated signaling pathway [GO:0022400]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; host cell [GO:0043657]; plasma membrane [GO:0005886]		glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]	metal ion binding [GO:0046872]; N-acetyltransferase activity [GO:0008080]
d4c2xa2_d2jdca1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; host cell [GO:0043657]; plasma membrane [GO:0005886]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; intracellular transport of virus [GO:0075733]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	intracellular transport of virus [GO:0075733]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; Golgi apparatus [GO:0005794]; host cell [GO:0043657]; plasma membrane [GO:0005886]		glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]	glucosamine 6-phosphate N-acetyltransferase activity [GO:0004343]
d4c2ya1_d1q2ca1__1	Metazoa		Chordata	Ciliophora	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]; cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]	histone acetyltransferase activity [GO:0004402]	cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of rhodopsin mediated signaling pathway [GO:0022400]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extrinsic component of membrane [GO:0019898]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]		glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; myristoyltransferase activity [GO:0019107]	histone acetyltransferase activity [GO:0004402]
d4c3hk__d3s14k___1	Fungi	Fungi	Ascomycota	Ascomycota	nucleolus [GO:0005730]; RNA polymerase I complex [GO:0005736]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; regulation of cell size [GO:0008361]; ribosome biogenesis [GO:0042254]; RNA polymerase I preinitiation complex assembly [GO:0001188]; transcription by RNA polymerase I [GO:0006360]; transcription elongation from RNA polymerase I promoter [GO:0006362]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]; DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]; ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; transcription, RNA-templated [GO:0001172]; tRNA transcription by RNA polymerase III [GO:0042797]	nucleolar large rRNA transcription by RNA polymerase I [GO:0042790]; regulation of cell size [GO:0008361]; ribosome biogenesis [GO:0042254]; RNA polymerase I preinitiation complex assembly [GO:0001188]; transcription by RNA polymerase I [GO:0006360]; transcription elongation from RNA polymerase I promoter [GO:0006362]	ribosome biogenesis [GO:0042254]; termination of RNA polymerase III transcription [GO:0006386]; transcription, RNA-templated [GO:0001172]; transcription by RNA polymerase I [GO:0006360]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]; tRNA transcription by RNA polymerase III [GO:0042797]	nucleolus [GO:0005730]; RNA polymerase I complex [GO:0005736]	cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA polymerase I complex [GO:0005736]; RNA polymerase II, core complex [GO:0005665]; RNA polymerase III complex [GO:0005666]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]	DNA binding [GO:0003677]; RNA polymerase I activity [GO:0001054]; zinc ion binding [GO:0008270]
d4c43a2_d4b4da2__1			Cyanobacteria	Proteobacteria	phycobilisome [GO:0030089]; ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]; oxidation-reduction process [GO:0055114]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]	oxidation-reduction process [GO:0055114]		phycobilisome [GO:0030089]		ferredoxin-NADP+ reductase activity [GO:0004324]; flavin adenine dinucleotide binding [GO:0050660]; NADP binding [GO:0050661]	ferredoxin-NADP+ reductase activity [GO:0004324]; nucleotide binding [GO:0000166]
d4c4kt__d4ozfa2__1	Metazoa	Metazoa	Chordata	Chordata	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; immune response [GO:0006955]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4c4ra__d3e81c___1			Firmicutes	Bacteroidetes	cytoplasm [GO:0005737]; beta-phosphoglucomutase activity [GO:0008801]; hydrolase activity [GO:0016787]; magnesium ion binding [GO:0000287]; carbohydrate metabolic process [GO:0005975]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]; lipopolysaccharide biosynthetic process [GO:0009103]	carbohydrate metabolic process [GO:0005975]	lipopolysaccharide biosynthetic process [GO:0009103]	cytoplasm [GO:0005737]		beta-phosphoglucomutase activity [GO:0008801]; hydrolase activity [GO:0016787]; magnesium ion binding [GO:0000287]	hydrolase activity, acting on ester bonds [GO:0016788]; metal ion binding [GO:0046872]
d4c4ta__d2autc___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; beta-phosphoglucomutase activity [GO:0008801]; hydrolase activity [GO:0016787]; magnesium ion binding [GO:0000287]; carbohydrate metabolic process [GO:0005975]	outer membrane-bounded periplasmic space [GO:0030288]; acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]	carbohydrate metabolic process [GO:0005975]		cytoplasm [GO:0005737]	outer membrane-bounded periplasmic space [GO:0030288]	beta-phosphoglucomutase activity [GO:0008801]; hydrolase activity [GO:0016787]; magnesium ion binding [GO:0000287]	acid phosphatase activity [GO:0003993]; metal ion binding [GO:0046872]
d4c4ud__d3qzba1__1			Euryarchaeota	Thermotogae	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]					iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4c4ul__d4bffi___1			Euryarchaeota	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]					iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4c4um__d4bffm___1			Euryarchaeota	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]					iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4c4un__d1vzgb1__1			Euryarchaeota	Proteobacteria	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]; removal of superoxide radicals [GO:0019430]		removal of superoxide radicals [GO:0019430]			iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4c4up__d4bgld___1			Euryarchaeota	Euryarchaeota	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]					iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]	iron ion binding [GO:0005506]; superoxide reductase activity [GO:0050605]
d4c4xb__d4dtcb2__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]; behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	behavioral fear response [GO:0001662]; cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; locomotory exploration behavior [GO:0035641]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell population proliferation [GO:0008284]; proteolysis [GO:0006508]; psychomotor behavior [GO:0036343]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]	apical plasma membrane [GO:0016324]; cell surface [GO:0009986]; endocytic vesicle [GO:0030139]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; intercellular canaliculus [GO:0046581]; invadopodium membrane [GO:0071438]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	dipeptidyl-peptidase activity [GO:0008239]; identical protein binding [GO:0042802]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; signaling receptor binding [GO:0005102]; virus receptor activity [GO:0001618]
d4c4ya__d3fvre___1	Metazoa		Chordata	Firmicutes	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	acetylesterase activity [GO:0008126]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	acetylesterase activity [GO:0008126]
d4c4zb__d4lxha___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]; 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]; cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]	hydrolase activity [GO:0016787]	cellular calcium ion homeostasis [GO:0006874]; cholesterol homeostasis [GO:0042632]; dephosphorylation [GO:0016311]; drug metabolic process [GO:0017144]; epoxide metabolic process [GO:0097176]; epoxygenase P450 pathway [GO:0019373]; inflammatory response [GO:0006954]; long-chain fatty acid biosynthetic process [GO:0042759]; phospholipid dephosphorylation [GO:0046839]; positive regulation of blood vessel diameter [GO:0097755]; positive regulation of gene expression [GO:0010628]; protein targeting to peroxisome [GO:0006625]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of cholesterol metabolic process [GO:0090181]; response to toxic substance [GO:0009636]; stilbene catabolic process [GO:0046272]; xenobiotic metabolic process [GO:0006805]		cell [GO:0005623]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; peroxisomal matrix [GO:0005782]; peroxisome [GO:0005777]		10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity [GO:0033885]; epoxide hydrolase activity [GO:0004301]; lipid phosphatase activity [GO:0042577]; magnesium ion binding [GO:0000287]; phosphatase activity [GO:0016791]; protein homodimerization activity [GO:0042803]; toxic substance binding [GO:0015643]	hydrolase activity [GO:0016787]
d4c50a2_d5kq3b2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d4c50b2_d5sxsb2__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d4c51a2_d1atja___1		Viridiplantae	Actinobacteria	Streptophyta	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; vacuole [GO:0005773]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d4c51b1_d3wxoa1__1			Actinobacteria	Cyanobacteria	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]		catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d4c51b2_d4fm5d2__1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]; cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cellular response to hydrogen peroxide [GO:0070301]; evasion or tolerance by symbiont of host-produced reactive oxygen species [GO:0052059]; hydrogen peroxide catabolic process [GO:0042744]; pathogenesis [GO:0009405]; positive regulation of DNA repair [GO:0045739]; response to oxidative stress [GO:0006979]	aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]	cell wall [GO:0005618]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADH binding [GO:0070404]; NADPH binding [GO:0070402]; oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor [GO:0016677]; peroxidase activity [GO:0004601]	enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d4c5aa2_d4xx0b1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]; ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	cytosol [GO:0005829]	mitochondrion [GO:0005739]; succinate-CoA ligase complex [GO:0042709]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	ATP binding [GO:0005524]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; succinate-CoA ligase (GDP-forming) activity [GO:0004776]
d4c5ab1_d5xi5f1__1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]; tubulin binding [GO:0015631]; microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	microtubule depolymerization [GO:0007019]; neuron projection development [GO:0031175]; regulation of cytoskeleton organization [GO:0051493]; regulation of microtubule polymerization or depolymerization [GO:0031110]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; neuron projection [GO:0043005]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	tubulin binding [GO:0015631]
d4c5ab2_d1w93a3__1		Fungi	Proteobacteria	Ascomycota	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]; acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]; acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	acetyl-CoA biosynthetic process [GO:0006085]; long-chain fatty acid biosynthetic process [GO:0042759]; malonyl-CoA biosynthetic process [GO:2001295]; protein import into nucleus [GO:0006606]	cytosol [GO:0005829]	acetyl-CoA carboxylase complex [GO:0009317]; cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; mitochondrion [GO:0005739]	ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	acetyl-CoA binding [GO:1905502]; acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; carboxyl- or carbamoyltransferase activity [GO:0016743]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; protein homodimerization activity [GO:0042803]
d4c5bb2_d2vpqb2__1			Proteobacteria	Firmicutes	cytosol [GO:0005829]; ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	cytosol [GO:0005829]		ATP binding [GO:0005524]; D-alanine-D-alanine ligase activity [GO:0008716]; metal ion binding [GO:0046872]	acetyl-CoA carboxylase activity [GO:0003989]; ATP binding [GO:0005524]; biotin carboxylase activity [GO:0004075]; metal ion binding [GO:0046872]
d4c5mb1_d1vm7b___1			Firmicutes	Thermotogae	ATP binding [GO:0005524]; phosphomethylpyrimidine kinase activity [GO:0008972]; thiamine biosynthetic process [GO:0009228]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]; D-ribose catabolic process [GO:0019303]	thiamine biosynthetic process [GO:0009228]	D-ribose catabolic process [GO:0019303]		cytosol [GO:0005829]	ATP binding [GO:0005524]; phosphomethylpyrimidine kinase activity [GO:0008972]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; ribokinase activity [GO:0004747]
d4c5wa2_d5pkya___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]; carnitine biosynthetic process [GO:0045329]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	carnitine biosynthetic process [GO:0045329]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d4c66a1_d5e9ma1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleus [GO:0005634]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d4c68a1_d5gcna___1			Apicomplexa	Ciliophora	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]	histone acetyltransferase activity [GO:0004402]	N-terminal protein myristoylation [GO:0006499]				glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]	histone acetyltransferase activity [GO:0004402]
d4c6aa__d3ztqh___1				Aquificae	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d4c6ua2_d1f91b1__1				Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d4c6va2_d2qnxa1__1				Actinobacteria		cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]; fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		fatty acid biosynthetic process [GO:0006633]; fatty acid elongation [GO:0030497]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]		cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty-acyl-CoA binding [GO:0000062]
d4c6wa2_d2cdhc1__1				Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d4c6wb2_d2c7za2__1		Viridiplantae		Streptophyta		endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]; acetyl-CoA C-acyltransferase activity [GO:0003988]; fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]		fatty acid beta-oxidation [GO:0006635]; glyoxysome organization [GO:0010111]; jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]; phenylacetate catabolic process [GO:0010124]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; response to wounding [GO:0009611]		endoplasmic reticulum [GO:0005783]; glyoxysome [GO:0009514]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; peroxisome [GO:0005777]; vacuolar membrane [GO:0005774]		acetyl-CoA C-acyltransferase activity [GO:0003988]
d4c6xa2_d5bnsb1__1				Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d4c6xb1_d3v4xa1__1				Firmicutes		hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]		isoprenoid biosynthetic process [GO:0008299]				hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d4c6xb2_d1teda2__1				Actinobacteria		transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]		chalcone biosynthetic process [GO:0009715]; fatty acid biosynthetic process [GO:0006633]				transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d4c6za1_d1e5ma1__1				Cyanobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]
d4c6za2_d1u0ua1__1		Viridiplantae		Streptophyta		cytoplasm [GO:0005737]; pinosylvin synthase activity [GO:0050198]; biosynthetic process [GO:0009058]		biosynthetic process [GO:0009058]		cytoplasm [GO:0005737]		pinosylvin synthase activity [GO:0050198]
d4c70a2_d4ewpd2__1				Actinobacteria		cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d4c70b1_d2vtzc2__1				Proteobacteria		cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]		poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]
d4c70b1_d5wx5b1__1		Viridiplantae		Streptophyta		transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; biosynthetic process [GO:0009058]		biosynthetic process [GO:0009058]				transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d4c70b2_d4ewpb2__1				Actinobacteria		cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d4c71a1_d1i86a2__1		Viridiplantae		Streptophyta		naringenin-chalcone synthase activity [GO:0016210]; chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]		chalcone biosynthetic process [GO:0009715]; flavonoid biosynthetic process [GO:0009813]				naringenin-chalcone synthase activity [GO:0016210]
d4c71b1_d1g5xc2__1				Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d4c71b2_d2wl6a1__1				Proteobacteria		cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]		poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]
d4c72a2_d1ulqe1__1				Deinococcus-Thermus		transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]						transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d4c72b1_d1u0ma2__1				Actinobacteria		transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]; melanin biosynthetic process [GO:0042438]		melanin biosynthetic process [GO:0042438]				transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747]
d4c72b1_d4ubvb1__1				Actinobacteria		acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]; cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]		cholesterol catabolic process [GO:0006707]; fatty acid beta-oxidation [GO:0006635]; pathogenesis [GO:0009405]; phenylacetate catabolic process [GO:0010124]				acetyl-CoA C-acyltransferase activity [GO:0003988]; identical protein binding [GO:0042802]
d4c72b2_d1tqye1__1				Actinobacteria		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]		antibiotic biosynthetic process [GO:0017000]; fatty acid biosynthetic process [GO:0006633]				3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d4c72b2_d2x3eb1__1				Proteobacteria		cytoplasm [GO:0005737]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]		cytoplasm [GO:0005737]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; beta-ketoacyl-acyl-carrier-protein synthase III activity [GO:0033818]
d4c73a1_d2aq7b2__1				Proteobacteria		cytosol [GO:0005829]; 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]		cytosol [GO:0005829]		3-oxoacyl-[acyl-carrier-protein] synthase activity [GO:0004315]
d4c73a2_d1qflc2__1				Proteobacteria		cytoplasm [GO:0005737]; acetyl-CoA C-acetyltransferase activity [GO:0003985]; poly-hydroxybutyrate biosynthetic process [GO:0042619]		poly-hydroxybutyrate biosynthetic process [GO:0042619]		cytoplasm [GO:0005737]		acetyl-CoA C-acetyltransferase activity [GO:0003985]
d4c73b1_d1oxhd1__1				Firmicutes		beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]; fatty acid biosynthetic process [GO:0006633]		fatty acid biosynthetic process [GO:0006633]				beta-ketoacyl-acyl-carrier-protein synthase II activity [GO:0033817]; metal ion binding [GO:0046872]
d4c73b2_d1tvza2__1				Firmicutes		hydroxymethylglutaryl-CoA synthase activity [GO:0004421]; isoprenoid biosynthetic process [GO:0008299]		isoprenoid biosynthetic process [GO:0008299]				hydroxymethylglutaryl-CoA synthase activity [GO:0004421]
d4c7db1_d2xpkb1__1			Actinobacteria	Firmicutes	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]; carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]; protein deglycosylation [GO:0006517]			beta-N-acetylhexosaminidase activity [GO:0004563]	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102571]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102167]; [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity [GO:0102166]; beta-N-acetylglucosaminidase activity [GO:0016231]; carbohydrate binding [GO:0030246]
d4c7fa2_d3lppa2__1		Metazoa	Actinobacteria	Chordata	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]; carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]		apical plasma membrane [GO:0016324]; brush border [GO:0005903]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	beta-N-acetylhexosaminidase activity [GO:0004563]	carbohydrate binding [GO:0030246]; oligo-1,6-glucosidase activity [GO:0004574]; sucrose alpha-glucosidase activity [GO:0004575]
d4c7fb1_d1c7sa4__1			Actinobacteria	Proteobacteria	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	periplasmic space [GO:0042597]; beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]		periplasmic space [GO:0042597]	beta-N-acetylhexosaminidase activity [GO:0004563]	beta-N-acetylhexosaminidase activity [GO:0004563]; N-acetyl-beta-D-galactosaminidase activity [GO:0102148]; polysaccharide binding [GO:0030247]
d4c7ga2_d5fcza2__1			Actinobacteria	Actinobacteria	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	beta-N-acetylhexosaminidase activity [GO:0004563]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]			beta-N-acetylhexosaminidase activity [GO:0004563]	beta-N-acetylhexosaminidase activity [GO:0004563]
d4c7ob2_d1k5dd___1		Metazoa	Proteobacteria	Chordata	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; signal recognition particle binding [GO:0005047]; protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]; androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]; androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	protein targeting [GO:0006605]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	androgen receptor signaling pathway [GO:0030521]; cell division [GO:0051301]; DNA metabolic process [GO:0006259]; GTP metabolic process [GO:0046039]; intracellular transport of virus [GO:0075733]; miRNA metabolic process [GO:0010586]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle organization [GO:0007052]; positive regulation of protein binding [GO:0032092]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein localization to nucleolus [GO:1902570]; regulation of cholesterol biosynthetic process [GO:0045540]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]	cytosol [GO:0005829]; extrinsic component of plasma membrane [GO:0019897]; intrinsic component of plasma membrane [GO:0031226]; membrane [GO:0016020]; plasma membrane [GO:0005886]	centriole [GO:0005814]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; host cell [GO:0043657]; melanosome [GO:0042470]; membrane [GO:0016020]; midbody [GO:0030496]; nuclear envelope [GO:0005635]; nuclear pore [GO:0005643]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; recycling endosome [GO:0055037]; RNA nuclear export complex [GO:0042565]	GTPase activity [GO:0003924]; GTP binding [GO:0005525]; signal recognition particle binding [GO:0005047]	androgen receptor binding [GO:0050681]; cadherin binding [GO:0045296]; chromatin binding [GO:0003682]; GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; protein heterodimerization activity [GO:0046982]; RNA binding [GO:0003723]
d4c7qa1_d1l3ka2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA processing [GO:0006397]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	mRNA processing [GO:0006397]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]
d4c7va2_d3exgx1__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]; pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]; acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; tricarboxylic acid cycle [GO:0006099]		mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pyruvate dehydrogenase complex [GO:0045254]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	pyruvate dehydrogenase (acetyl-transferring) activity [GO:0004739]
d4c7va3_d1olub2__1		Metazoa	Firmicutes	Chordata	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]; branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]		branched-chain amino acid catabolic process [GO:0009083]; response to nutrient [GO:0007584]		mitochondrial alpha-ketoglutarate dehydrogenase complex [GO:0005947]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO:0003863]; alpha-ketoacid dehydrogenase activity [GO:0003826]
d4c7va3_d5hjea3__1		Fungi	Firmicutes	Ascomycota	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]					metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d4c7xa1_d1trka1__1		Fungi	Firmicutes	Ascomycota	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]		pentose-phosphate shunt [GO:0006098]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d4c7xa1_d2vk8d3__1		Fungi	Firmicutes	Ascomycota	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]; aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		aromatic amino acid family catabolic process to alcohol via Ehrlich pathway [GO:0000949]; branched-chain amino acid catabolic process [GO:0009083]; glycolytic fermentation to ethanol [GO:0019655]; L-phenylalanine catabolic process [GO:0006559]; pyruvate metabolic process [GO:0006090]; tryptophan catabolic process [GO:0006569]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	branched-chain-2-oxoacid decarboxylase activity [GO:0047433]; carboxy-lyase activity [GO:0016831]; indolepyruvate decarboxylase activity [GO:0047434]; magnesium ion binding [GO:0000287]; phenylpyruvate decarboxylase activity [GO:0050177]; pyruvate decarboxylase activity [GO:0004737]; thiamine pyrophosphate binding [GO:0030976]
d4c7xa3_d1r9jb3__1			Firmicutes		metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]					metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]
d4c7xa3_d5nd6b3__1		Viridiplantae	Firmicutes	Chlorophyta	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	cytosol [GO:0005829]; transketolase activity [GO:0004802]; pentose-phosphate shunt [GO:0006098]		pentose-phosphate shunt [GO:0006098]		cytosol [GO:0005829]	metal ion binding [GO:0046872]; transketolase activity [GO:0004802]	transketolase activity [GO:0004802]
d4c7ya4_d3eubu2__1		Metazoa	Proteobacteria	Chordata	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]; 2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]; xanthine catabolic process [GO:0009115]		xanthine catabolic process [GO:0009115]		cytosol [GO:0005829]; extracellular space [GO:0005615]; peroxisome [GO:0005777]; xanthine dehydrogenase complex [GO:0002197]	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	2 iron, 2 sulfur cluster binding [GO:0051537]; electron transfer activity [GO:0009055]; FAD binding [GO:0071949]; flavin adenine dinucleotide binding [GO:0050660]; iron ion binding [GO:0005506]; molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; protein homodimerization activity [GO:0042803]; xanthine dehydrogenase activity [GO:0004854]; xanthine oxidase activity [GO:0004855]
d4c7za1_d4xdcb1__1			Proteobacteria	Firmicutes	2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]					2 iron, 2 sulfur cluster binding [GO:0051537]; aldehyde dehydrogenase (FAD-independent) activity [GO:0033727]; electron transfer activity [GO:0009055]; metal ion binding [GO:0046872]	4 iron, 4 sulfur cluster binding [GO:0051539]; electron transfer activity [GO:0009055]; ferredoxin hydrogenase activity [GO:0008901]; iron ion binding [GO:0005506]
d4c83b2_d2q87a___1		Metazoa		Chordata		extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]; phosphatidylethanolamine binding [GO:0008429]; phosphatidylserine binding [GO:0001786]; signaling receptor activity [GO:0038023]; cell adhesion [GO:0007155]; negative regulation of activation of Janus kinase activity [GO:1902569]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of eosinophil activation [GO:1902567]; negative regulation of eosinophil migration [GO:2000417]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mast cell activation involved in immune response [GO:0033007]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034125]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of NK T cell activation [GO:0051134]; negative regulation of phagocytosis, engulfment [GO:0060101]; neutrophil degranulation [GO:0043312]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; regulation of immune response [GO:0050776]; regulation of T cell receptor signaling pathway [GO:0050856]		cell adhesion [GO:0007155]; negative regulation of activation of Janus kinase activity [GO:1902569]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of B cell receptor signaling pathway [GO:0050859]; negative regulation of eosinophil activation [GO:1902567]; negative regulation of eosinophil migration [GO:2000417]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mast cell activation involved in immune response [GO:0033007]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034125]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of NK T cell activation [GO:0051134]; negative regulation of phagocytosis, engulfment [GO:0060101]; neutrophil degranulation [GO:0043312]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; regulation of immune response [GO:0050776]; regulation of T cell receptor signaling pathway [GO:0050856]		extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886]; tertiary granule membrane [GO:0070821]		phosphatidylethanolamine binding [GO:0008429]; phosphatidylserine binding [GO:0001786]; signaling receptor activity [GO:0038023]
d4c83d2_d4hwbl2__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; interleukin-13 receptor complex [GO:0005898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-2 binding [GO:0019976]; cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]		cell surface receptor signaling pathway [GO:0007166]; cytokine-mediated signaling pathway [GO:0019221]		external side of plasma membrane [GO:0009897]; interleukin-13 receptor complex [GO:0005898]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]		cytokine binding [GO:0019955]; cytokine receptor activity [GO:0004896]; interleukin-2 binding [GO:0019976]
d4c8rd2_d5fp8a___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]; carnitine biosynthetic process [GO:0045329]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]; cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	carnitine biosynthetic process [GO:0045329]	cellular response to ionizing radiation [GO:0071479]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of chromatin binding [GO:0035563]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of protein phosphorylation [GO:0001932]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]	blood microparticle [GO:0072562]; histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; pericentric heterochromatin [GO:0005721]; site of double-strand break [GO:0035861]	gamma-butyrobetaine dioxygenase activity [GO:0008336]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; zinc ion binding [GO:0008270]	chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; dioxygenase activity [GO:0051213]; histone demethylase activity [GO:0032452]; histone demethylase activity (H3-K9 specific) [GO:0032454]; metal ion binding [GO:0046872]
d4c8xa__d4b9ca1__1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]		integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]	cellulose binding [GO:0030248]; metal ion binding [GO:0046872]
d4c8xb__d4fl4b___1			Firmicutes	Firmicutes	cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]; polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]	polysaccharide catabolic process [GO:0000272]			cellulase activity [GO:0008810]; cellulose binding [GO:0030248]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; metal ion binding [GO:0046872]
d4c92e__d1th7e2__1	Fungi		Ascomycota	Crenarchaeota	Lsm1-7-Pat1 complex [GO:1990726]; nucleolus [GO:0005730]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]; RNA binding [GO:0003723]; maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]		maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]		Lsm1-7-Pat1 complex [GO:1990726]; nucleolus [GO:0005730]; P-body [GO:0000932]; small nucleolar ribonucleoprotein complex [GO:0005732]; spliceosomal complex [GO:0005681]; U4/U6 x U5 tri-snRNP complex [GO:0046540]; U6 snRNP [GO:0005688]		RNA binding [GO:0003723]	
d4c94b1_d2b24c2__1	Viridiplantae		Streptophyta	Actinobacteria	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	cellular metabolic process [GO:0044237]			abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]
d4c94b1_d2yflc2__1	Viridiplantae		Streptophyta	Proteobacteria	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	biphenyl 2,3-dioxygenase activity [GO:0018687]; aromatic compound catabolic process [GO:0019439]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	aromatic compound catabolic process [GO:0019439]			abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	biphenyl 2,3-dioxygenase activity [GO:0018687]
d4c94c1_d1fskg___1	Viridiplantae	Metazoa	Streptophyta	Chordata	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4c94e1_d1x53a1__1	Viridiplantae	Metazoa	Streptophyta	Chordata	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; ATPase activator activity [GO:0001671]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; Hsp90 protein binding [GO:0051879]; positive regulation of ATPase activity [GO:0032781]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	positive regulation of ATPase activity [GO:0032781]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	ATPase activator activity [GO:0001671]; cadherin binding [GO:0045296]; chaperone binding [GO:0051087]; Hsp90 protein binding [GO:0051879]
d4c9fd1_d3g81a1__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; (1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]; carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]; cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	cellular protein metabolic process [GO:0044267]; defense response to bacterium [GO:0042742]; developmental process [GO:0032502]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; lung alveolus development [GO:0048286]; macrophage chemotaxis [GO:0048246]; negative regulation by host of symbiont molecular function [GO:0052405]; negative regulation of interleukin-2 biosynthetic process [GO:0045085]; negative regulation of T cell proliferation [GO:0042130]; positive regulation of phagocytosis [GO:0050766]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; regulation of adhesion of symbiont to host epithelial cell [GO:1905226]; regulation of cytokine production [GO:0001817]; regulation of immune response [GO:0050776]; respiratory gaseous exchange by respiratory system [GO:0007585]; surfactant homeostasis [GO:0043129]; toll-like receptor signaling pathway [GO:0002224]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	clathrin-coated endocytic vesicle [GO:0045334]; collagen trimer [GO:0005581]; endocytic vesicle [GO:0030139]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lysosome [GO:0005764]; multivesicular body [GO:0005771]; rough endoplasmic reticulum [GO:0005791]	(1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; identical protein binding [GO:0042802]; lipopolysaccharide binding [GO:0001530]; monosaccharide binding [GO:0048029]
d4c9ia1_d4z3lc___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	abscisic acid binding [GO:0010427]; flavonoid binding [GO:0097243]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]	abscisic acid binding [GO:0010427]; flavonoid binding [GO:0097243]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d4c9ib1_d3gcfg2__1	Viridiplantae		Streptophyta	Actinobacteria	abscisic acid binding [GO:0010427]; flavonoid binding [GO:0097243]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]				abscisic acid binding [GO:0010427]; flavonoid binding [GO:0097243]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; metal ion binding [GO:0046872]
d4c9ic1_d1tw0a1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	abscisic acid binding [GO:0010427]; flavonoid binding [GO:0097243]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]			abscisic acid binding [GO:0010427]; flavonoid binding [GO:0097243]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d4c9if1_d4a8ua___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	abscisic acid binding [GO:0010427]; flavonoid binding [GO:0097243]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	cytoplasm [GO:0005737]; abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]; abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; flavonoid biosynthetic process [GO:0009813]; response to biotic stimulus [GO:0009607]	abscisic acid-activated signaling pathway [GO:0009738]; defense response [GO:0006952]; response to biotic stimulus [GO:0009607]		cytoplasm [GO:0005737]	abscisic acid binding [GO:0010427]; flavonoid binding [GO:0097243]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]	abscisic acid binding [GO:0010427]; protein phosphatase inhibitor activity [GO:0004864]; signaling receptor activity [GO:0038023]
d4c9ma__d1ea1a___1			Proteobacteria	Actinobacteria	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytosol [GO:0005829]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]; oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]		oxidation-reduction process [GO:0055114]; sterol biosynthetic process [GO:0016126]; sterol metabolic process [GO:0016125]	integral component of membrane [GO:0016021]	cytosol [GO:0005829]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; sterol 14-demethylase activity [GO:0008398]
d4c9ma__d2y5nb1__1			Proteobacteria	Actinobacteria	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]; antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]		antibiotic biosynthetic process [GO:0017000]; oxidation-reduction process [GO:0055114]	integral component of membrane [GO:0016021]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d4c9nb__d1jfca___1		Fungi	Proteobacteria	Ascomycota	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]			integral component of membrane [GO:0016021]		heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; nitric oxide reductase activity (NAD(P)H-dependent) activity [GO:0102199]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d4c9oa__d3t3sc___1		Metazoa	Proteobacteria	Chordata	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]; arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]; coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]		coumarin metabolic process [GO:0009804]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; organic acid metabolic process [GO:0006082]; oxidation-reduction process [GO:0055114]; xenobiotic metabolic process [GO:0006805]	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; intracellular membrane-bounded organelle [GO:0043231]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	arachidonic acid epoxygenase activity [GO:0008392]; aromatase activity [GO:0070330]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [GO:0016712]; steroid hydroxylase activity [GO:0008395]
d4c9pb__d5wk7a___1			Proteobacteria	Proteobacteria	integral component of membrane [GO:0016021]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]		(+)-camphor catabolic process [GO:0019383]	integral component of membrane [GO:0016021]	cytoplasm [GO:0005737]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d4c9xa__d1q54b1__1	Metazoa		Chordata	Proteobacteria	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTP diphosphatase activity [GO:0036219]; GTPase activity [GO:0003924]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]; aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	cytoplasm [GO:0005737]; hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	aging [GO:0007568]; dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	cellular response to DNA damage stimulus [GO:0006974]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isoprenoid biosynthetic process [GO:0008299]	acrosomal vesicle [GO:0001669]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity [GO:0035539]; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [GO:0008413]; ATP diphosphatase activity [GO:0047693]; GTPase activity [GO:0003924]; GTP diphosphatase activity [GO:0036219]; metal ion binding [GO:0046872]; snoRNA binding [GO:0030515]	hydrolase activity [GO:0016787]; isopentenyl-diphosphate delta-isomerase activity [GO:0004452]; metal ion binding [GO:0046872]
d4ca4a__d1rxla1__1			Proteobacteria	Proteobacteria	pilus [GO:0009289]; cell adhesion [GO:0007155]	pilus [GO:0009289]	cell adhesion [GO:0007155]		pilus [GO:0009289]	pilus [GO:0009289]		
d4ca4a__d4x5rb___1			Proteobacteria	Proteobacteria	pilus [GO:0009289]; cell adhesion [GO:0007155]	host cell membrane [GO:0033644]; pilus [GO:0009289]; mannose binding [GO:0005537]; cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	cell adhesion [GO:0007155]	cell adhesion [GO:0007155]; cell adhesion involved in single-species biofilm formation [GO:0043709]; pilus organization [GO:0043711]	pilus [GO:0009289]	host cell membrane [GO:0033644]; pilus [GO:0009289]		mannose binding [GO:0005537]
d4ca5a__d3d0hb___1	Metazoa	Metazoa	Chordata	Chordata	endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; bradykinin receptor binding [GO:0031711]; carboxypeptidase activity [GO:0004180]; chloride ion binding [GO:0031404]; dipeptidyl-peptidase activity [GO:0008239]; drug binding [GO:0008144]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallodipeptidase activity [GO:0070573]; metallopeptidase activity [GO:0008237]; mitogen-activated protein kinase binding [GO:0051019]; mitogen-activated protein kinase kinase binding [GO:0031434]; peptidyl-dipeptidase activity [GO:0008241]; tripeptidyl-peptidase activity [GO:0008240]; zinc ion binding [GO:0008270]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of blood pressure [GO:0045777]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; posttranscriptional regulation of gene expression [GO:0010608]; proteolysis [GO:0006508]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of blood vessel diameter [GO:0097746]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; spermatogenesis [GO:0007283]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]; angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of blood pressure [GO:0045777]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; posttranscriptional regulation of gene expression [GO:0010608]; proteolysis [GO:0006508]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of blood vessel diameter [GO:0097746]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; spermatogenesis [GO:0007283]	angiotensin maturation [GO:0002003]; angiotensin-mediated drinking behavior [GO:0003051]; positive regulation of amino acid transport [GO:0051957]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; receptor biosynthetic process [GO:0032800]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of blood vessel diameter [GO:0097746]; regulation of cardiac conduction [GO:1903779]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production [GO:0001817]; regulation of inflammatory response [GO:0050727]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; tryptophan transport [GO:0015827]; viral entry into host cell [GO:0046718]	endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; plasma membrane [GO:0005886]	brush border membrane [GO:0031526]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]	actin binding [GO:0003779]; bradykinin receptor binding [GO:0031711]; carboxypeptidase activity [GO:0004180]; chloride ion binding [GO:0031404]; dipeptidyl-peptidase activity [GO:0008239]; drug binding [GO:0008144]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallodipeptidase activity [GO:0070573]; metallopeptidase activity [GO:0008237]; mitogen-activated protein kinase binding [GO:0051019]; mitogen-activated protein kinase kinase binding [GO:0031434]; peptidyl-dipeptidase activity [GO:0008241]; tripeptidyl-peptidase activity [GO:0008240]; zinc ion binding [GO:0008270]	carboxypeptidase activity [GO:0004180]; dipeptidyl-peptidase activity [GO:0008239]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallocarboxypeptidase activity [GO:0004181]; metallopeptidase activity [GO:0008237]; peptidyl-dipeptidase activity [GO:0008241]; virus receptor activity [GO:0001618]; zinc ion binding [GO:0008270]
d4ca5a__d3ehxa___1	Metazoa	Metazoa	Chordata	Chordata	endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; plasma membrane [GO:0005886]; actin binding [GO:0003779]; bradykinin receptor binding [GO:0031711]; carboxypeptidase activity [GO:0004180]; chloride ion binding [GO:0031404]; dipeptidyl-peptidase activity [GO:0008239]; drug binding [GO:0008144]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallodipeptidase activity [GO:0070573]; metallopeptidase activity [GO:0008237]; mitogen-activated protein kinase binding [GO:0051019]; mitogen-activated protein kinase kinase binding [GO:0031434]; peptidyl-dipeptidase activity [GO:0008241]; tripeptidyl-peptidase activity [GO:0008240]; zinc ion binding [GO:0008270]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of blood pressure [GO:0045777]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; posttranscriptional regulation of gene expression [GO:0010608]; proteolysis [GO:0006508]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of blood vessel diameter [GO:0097746]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; spermatogenesis [GO:0007283]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of blood pressure [GO:0045777]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of systemic arterial blood pressure [GO:0003084]; posttranscriptional regulation of gene expression [GO:0010608]; proteolysis [GO:0006508]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of blood vessel diameter [GO:0097746]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; spermatogenesis [GO:0007283]	cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of interferon-alpha secretion [GO:1902741]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; response to amyloid-beta [GO:1904645]; wound healing, spreading of epidermal cells [GO:0035313]	endosome [GO:0005768]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lysosome [GO:0005764]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; extracellular matrix [GO:0031012]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]	actin binding [GO:0003779]; bradykinin receptor binding [GO:0031711]; carboxypeptidase activity [GO:0004180]; chloride ion binding [GO:0031404]; dipeptidyl-peptidase activity [GO:0008239]; drug binding [GO:0008144]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metallodipeptidase activity [GO:0070573]; metallopeptidase activity [GO:0008237]; mitogen-activated protein kinase binding [GO:0051019]; mitogen-activated protein kinase kinase binding [GO:0031434]; peptidyl-dipeptidase activity [GO:0008241]; tripeptidyl-peptidase activity [GO:0008240]; zinc ion binding [GO:0008270]	calcium ion binding [GO:0005509]; collagen binding [GO:0005518]; core promoter binding [GO:0001047]; endopeptidase activity [GO:0004175]; metalloendopeptidase activity [GO:0004222]; sequence-specific DNA binding [GO:0043565]; zinc ion binding [GO:0008270]
d4cada1_d5c3ta1__1		Metazoa	Euryarchaeota	Chordata	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]; CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]; cellular response to lipopolysaccharide [GO:0071222]; immune response [GO:0006955]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of CD8-positive, alpha-beta T cell activation [GO:2001186]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of tumor necrosis factor superfamily cytokine production [GO:1903556]; positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process [GO:1905404]; positive regulation of cell migration [GO:0030335]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of tolerance induction to tumor cell [GO:0002845]; response to cytokine [GO:0034097]; signal transduction [GO:0007165]; T cell costimulation [GO:0031295]; toxin transport [GO:1901998]	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; early endosome membrane [GO:0031901]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]	cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]	
d4cadd1_d2po6e1__1		Metazoa	Euryarchaeota	Chordata	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]; CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4cadd2_d3l1ol1__1			Euryarchaeota		integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]; CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]		CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]		integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]		cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]	
d4cadg1_d5b8cc1__1		Metazoa	Euryarchaeota	Chordata	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]; CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]	adaptive immune response [GO:0002250]; apoptotic process [GO:0006915]; humoral immune response [GO:0006959]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of immune response [GO:0050777]; negative regulation of tolerance induction [GO:0002644]; positive regulation of T cell apoptotic process [GO:0070234]; T cell costimulation [GO:0031295]	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]	
d4cadg2_d3q5yd2__1			Euryarchaeota		integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]; CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]		CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]		integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]		cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]	
d4cadj2_d1p7ka1__1		Metazoa	Euryarchaeota	Chordata	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]; cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]; CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]	B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]	integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886]	external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	cysteine-type endopeptidase activity [GO:0004197]; endopeptidase activity [GO:0004175]; peptidase activity [GO:0008233]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4caea1_d1qsoc___1		Fungi	Apicomplexa	Ascomycota	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]	cytoplasm [GO:0005737]; histone acetyltransferase activity [GO:0004402]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]; protein acetylation [GO:0006473]	N-terminal protein myristoylation [GO:0006499]	protein acetylation [GO:0006473]		cytoplasm [GO:0005737]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]	histone acetyltransferase activity [GO:0004402]; identical protein binding [GO:0042802]; N-acetyltransferase activity [GO:0008080]
d4cafa1_d2z3nb___1			Apicomplexa	Proteobacteria	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal protein myristoylation [GO:0006499]	cytoplasm [GO:0005737]; leucyltransferase activity [GO:0008914]; transferase activity, transferring amino-acyl groups [GO:0016755]; protein catabolic process [GO:0030163]	N-terminal protein myristoylation [GO:0006499]	protein catabolic process [GO:0030163]		cytoplasm [GO:0005737]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]	leucyltransferase activity [GO:0008914]; transferase activity, transferring amino-acyl groups [GO:0016755]
d4caja__d3rs1a___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; (1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; carbohydrate binding [GO:0030246]; natural killer cell lectin-like receptor binding [GO:0046703]; transmembrane signaling receptor activity [GO:0004888]; membrane raft assembly [GO:0001765]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of immunological synapse formation [GO:2000522]; receptor clustering [GO:0043113]; regulation of actin filament polymerization [GO:0030833]; regulation of interleukin-2 biosynthetic process [GO:0045076]; regulation of T cell proliferation [GO:0042129]; T cell receptor signaling pathway [GO:0050852]	detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	membrane raft assembly [GO:0001765]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of immunological synapse formation [GO:2000522]; receptor clustering [GO:0043113]; regulation of actin filament polymerization [GO:0030833]; regulation of interleukin-2 biosynthetic process [GO:0045076]; regulation of T cell proliferation [GO:0042129]; T cell receptor signaling pathway [GO:0050852]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	(1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]	carbohydrate binding [GO:0030246]; natural killer cell lectin-like receptor binding [GO:0046703]; transmembrane signaling receptor activity [GO:0004888]
d4cajb__d1afb21__1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; (1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	collagen trimer [GO:0005581]; collagen-containing extracellular matrix [GO:0062023]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]; calcium ion binding [GO:0005509]; calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]; complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-positive bacterium [GO:0050830]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; killing by host of symbiont cells [GO:0051873]; positive regulation of phagocytosis [GO:0050766]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	collagen-containing extracellular matrix [GO:0062023]; collagen trimer [GO:0005581]; extracellular matrix [GO:0031012]; extracellular space [GO:0005615]	(1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]	calcium-dependent carbohydrate binding [GO:0120153]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; mannose binding [GO:0005537]; oligosaccharide binding [GO:0070492]; phosphatidylinositol-4-phosphate binding [GO:0070273]; polysaccharide binding [GO:0030247]; protease binding [GO:0002020]; protein homodimerization activity [GO:0042803]
d4cajd__d5thpe___1	Metazoa	Metazoa	Chordata	Chordata	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]; (1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]; detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	axon terminus [GO:0043679]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha2-beta1 complex [GO:0034666]; integrin complex [GO:0008305]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; amyloid-beta binding [GO:0001540]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; collagen receptor activity [GO:0038064]; heparan sulfate proteoglycan binding [GO:0043395]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein-containing complex binding [GO:0044877]; virus receptor activity [GO:0001618]; animal organ morphogenesis [GO:0009887]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell population proliferation [GO:0008283]; cell-matrix adhesion [GO:0007160]; cell-substrate adhesion [GO:0031589]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; collagen-activated signaling pathway [GO:0038065]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; focal adhesion assembly [GO:0048041]; hepatocyte differentiation [GO:0070365]; hypotonic response [GO:0006971]; integrin-mediated signaling pathway [GO:0007229]; mammary gland development [GO:0030879]; mesodermal cell differentiation [GO:0048333]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell projection organization [GO:0031346]; positive regulation of collagen binding [GO:0033343]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of translation [GO:0045727]; positive regulation of transmission of nerve impulse [GO:0051971]; response to amine [GO:0014075]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to L-ascorbic acid [GO:0033591]; response to muscle activity [GO:0014850]; response to parathyroid hormone [GO:0071107]; skin morphogenesis [GO:0043589]; substrate-dependent cell migration [GO:0006929]	detection of bacterium [GO:0016045]; detection of yeast [GO:0001879]; endocytosis [GO:0006897]; phagocytosis, recognition [GO:0006910]; positive regulation of phagocytosis [GO:0050766]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]	animal organ morphogenesis [GO:0009887]; blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell population proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular response to estradiol stimulus [GO:0071392]; cellular response to mechanical stimulus [GO:0071260]; collagen-activated signaling pathway [GO:0038065]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; female pregnancy [GO:0007565]; focal adhesion assembly [GO:0048041]; hepatocyte differentiation [GO:0070365]; hypotonic response [GO:0006971]; integrin-mediated signaling pathway [GO:0007229]; mammary gland development [GO:0030879]; mesodermal cell differentiation [GO:0048333]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell projection organization [GO:0031346]; positive regulation of collagen binding [GO:0033343]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA binding [GO:0043388]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of inflammatory response [GO:0050729]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of translation [GO:0045727]; positive regulation of transmission of nerve impulse [GO:0051971]; response to amine [GO:0014075]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to L-ascorbic acid [GO:0033591]; response to muscle activity [GO:0014850]; response to parathyroid hormone [GO:0071107]; skin morphogenesis [GO:0043589]; substrate-dependent cell migration [GO:0006929]	external side of plasma membrane [GO:0009897]; integral component of membrane [GO:0016021]	axon terminus [GO:0043679]; basal part of cell [GO:0045178]; cell surface [GO:0009986]; external side of plasma membrane [GO:0009897]; focal adhesion [GO:0005925]; integrin alpha2-beta1 complex [GO:0034666]; integrin complex [GO:0008305]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]	(1->3)-beta-D-glucan binding [GO:0001872]; mannose binding [GO:0005537]; metal ion binding [GO:0046872]; polysaccharide binding [GO:0030247]	amyloid-beta binding [GO:0001540]; collagen binding [GO:0005518]; collagen binding involved in cell-matrix adhesion [GO:0098639]; collagen receptor activity [GO:0038064]; heparan sulfate proteoglycan binding [GO:0043395]; integrin binding [GO:0005178]; laminin binding [GO:0043236]; metal ion binding [GO:0046872]; protein-containing complex binding [GO:0044877]; protein heterodimerization activity [GO:0046982]; virus receptor activity [GO:0001618]
d4cava1_d2z3mb___1	Fungi		Ascomycota	Proteobacteria	cytoplasm [GO:0005737]; glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]	cytoplasm [GO:0005737]; leucyltransferase activity [GO:0008914]; transferase activity, transferring amino-acyl groups [GO:0016755]; protein catabolic process [GO:0030163]	N-terminal peptidyl-glycine N-myristoylation [GO:0018008]	protein catabolic process [GO:0030163]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	glycylpeptide N-tetradecanoyltransferase activity [GO:0004379]	leucyltransferase activity [GO:0008914]; transferase activity, transferring amino-acyl groups [GO:0016755]
d4cayb__d1hq3d___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; Swr1 complex [GO:0000812]; histone binding [GO:0042393]; phosphatase inhibitor activity [GO:0019212]; histone exchange [GO:0043486]	nucleosome [GO:0000786]; nucleus [GO:0005634]; DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]	histone exchange [GO:0043486]		cytoplasmic vesicle [GO:0031410]; nucleus [GO:0005634]; Swr1 complex [GO:0000812]	nucleosome [GO:0000786]; nucleus [GO:0005634]	histone binding [GO:0042393]; phosphatase inhibitor activity [GO:0019212]	DNA binding [GO:0003677]; protein heterodimerization activity [GO:0046982]
d4cazb__d1of7a___1			Proteobacteria		aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]		glycine betaine biosynthetic process from choline [GO:0019285]				aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	
d4cazb__d3r31b___1			Proteobacteria	Proteobacteria	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	glycine betaine biosynthetic process from choline [GO:0019285]	glycine betaine biosynthetic process from choline [GO:0019285]			aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]
d4cbba__d1a4sd___1		Metazoa	Proteobacteria	Chordata	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	cytosol [GO:0005829]; 4-trimethylammoniobutyraldehyde dehydrogenase activity [GO:0047105]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; carnitine biosynthetic process [GO:0045329]	glycine betaine biosynthetic process from choline [GO:0019285]	carnitine biosynthetic process [GO:0045329]		cytosol [GO:0005829]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	4-trimethylammoniobutyraldehyde dehydrogenase activity [GO:0047105]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]
d4cbbd__d3szaa___1		Metazoa	Proteobacteria	Chordata	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]; aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	glycine betaine biosynthetic process from choline [GO:0019285]	aging [GO:0007568]; cellular aldehyde metabolic process [GO:0006081]; oxidation-reduction process [GO:0055114]; positive regulation of cell population proliferation [GO:0008284]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]		cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; alcohol dehydrogenase (NADP+) activity [GO:0008106]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; aldehyde dehydrogenase [NAD(P)+] activity [GO:0004030]; benzaldehyde dehydrogenase (NAD+) activity [GO:0018479]
d4cbbf__d4qgkb1__1		Metazoa	Proteobacteria	Chordata	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]; glycine betaine biosynthetic process from choline [GO:0019285]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]; 3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; long-chain-alcohol oxidase activity [GO:0046577]; long-chain-aldehyde dehydrogenase activity [GO:0050061]; medium-chain-aldehyde dehydrogenase activity [GO:0052814]; protein homodimerization activity [GO:0042803]; cellular aldehyde metabolic process [GO:0006081]; central nervous system development [GO:0007417]; epidermis development [GO:0008544]; fatty acid alpha-oxidation [GO:0001561]; hexadecanal metabolic process [GO:0046458]; oxidation-reduction process [GO:0055114]; peripheral nervous system development [GO:0007422]; phytol metabolic process [GO:0033306]; sesquiterpenoid metabolic process [GO:0006714]; sphingolipid biosynthetic process [GO:0030148]	glycine betaine biosynthetic process from choline [GO:0019285]	cellular aldehyde metabolic process [GO:0006081]; central nervous system development [GO:0007417]; epidermis development [GO:0008544]; fatty acid alpha-oxidation [GO:0001561]; hexadecanal metabolic process [GO:0046458]; oxidation-reduction process [GO:0055114]; peripheral nervous system development [GO:0007422]; phytol metabolic process [GO:0033306]; sesquiterpenoid metabolic process [GO:0006714]; sphingolipid biosynthetic process [GO:0030148]		endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777]	aldehyde dehydrogenase (NAD+) activity [GO:0004029]; betaine-aldehyde dehydrogenase activity [GO:0008802]; metal ion binding [GO:0046872]	3-chloroallyl aldehyde dehydrogenase activity [GO:0004028]; aldehyde dehydrogenase (NAD+) activity [GO:0004029]; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity [GO:0043878]; long-chain-alcohol oxidase activity [GO:0046577]; long-chain-aldehyde dehydrogenase activity [GO:0050061]; medium-chain-aldehyde dehydrogenase activity [GO:0052814]; protein homodimerization activity [GO:0042803]
d4cbua2_d3ezwg1__1	Metazoa		Chordata	Proteobacteria	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; actin polymerization or depolymerization [GO:0008154]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; barbed-end actin filament capping [GO:0051016]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]; vesicle-mediated transport [GO:0016192]	cytosol [GO:0005829]; ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]; cellular response to DNA damage stimulus [GO:0006974]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; glycerol-3-phosphate metabolic process [GO:0006072]; phosphorylation [GO:0016310]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; actin polymerization or depolymerization [GO:0008154]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; barbed-end actin filament capping [GO:0051016]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]; vesicle-mediated transport [GO:0016192]	cellular response to DNA damage stimulus [GO:0006974]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; phosphorylation [GO:0016310]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]	cytosol [GO:0005829]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	ATP binding [GO:0005524]; glycerol kinase activity [GO:0004370]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]
d4cbug__d3ffka3__1	Metazoa	Metazoa	Chordata	Chordata	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]; actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; actin polymerization or depolymerization [GO:0008154]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; barbed-end actin filament capping [GO:0051016]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]; vesicle-mediated transport [GO:0016192]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin filament capping [GO:0051693]; actin filament polymerization [GO:0030041]; actin filament reorganization [GO:0090527]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; actin polymerization or depolymerization [GO:0008154]; aging [GO:0007568]; amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; barbed-end actin filament capping [GO:0051016]; cellular response to cadmium ion [GO:0071276]; cellular response to interferon-gamma [GO:0071346]; cilium assembly [GO:0060271]; hepatocyte apoptotic process [GO:0097284]; negative regulation of viral entry into host cell [GO:0046597]; oligodendrocyte development [GO:0014003]; phagocytosis, engulfment [GO:0006911]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin nucleation [GO:0051127]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of gene expression [GO:0010628]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein destabilization [GO:0031648]; regulation of cell adhesion [GO:0030155]; regulation of establishment of T cell polarity [GO:1903903]; regulation of plasma membrane raft polarization [GO:1903906]; regulation of podosome assembly [GO:0071801]; regulation of receptor clustering [GO:1903909]; renal protein absorption [GO:0097017]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; sequestering of actin monomers [GO:0042989]; striated muscle atrophy [GO:0014891]; tissue regeneration [GO:0042246]; vesicle-mediated transport [GO:0016192]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	actin cap [GO:0030478]; actin cytoskeleton [GO:0015629]; cell [GO:0005623]; cortical actin cytoskeleton [GO:0030864]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; lamellipodium [GO:0030027]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; podosome [GO:0002102]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; sarcoplasm [GO:0016528]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; calcium ion binding [GO:0005509]; myosin II binding [GO:0045159]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d4cbxg__d1t3ya___1		Metazoa	Apicomplexa	Chordata	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; ATP binding [GO:0005524]	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; site of polarized growth [GO:0030427]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]; defense response to fungus [GO:0050832]; neutrophil degranulation [GO:0043312]; regulation of actin filament polymerization [GO:0030833]		defense response to fungus [GO:0050832]; neutrophil degranulation [GO:0043312]; regulation of actin filament polymerization [GO:0030833]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]	cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule lumen [GO:0034774]; site of polarized growth [GO:0030427]	ATP binding [GO:0005524]	actin binding [GO:0003779]; actin filament binding [GO:0051015]; enzyme binding [GO:0019899]
d4cbyb__d2pqoa___1	Metazoa		Chordata		A band [GO:0031672]; actomyosin [GO:0042641]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; neuromuscular junction [GO:0031594]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; Z disc [GO:0030018]; activating transcription factor binding [GO:0033613]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; potassium ion binding [GO:0030955]; promoter-specific chromatin binding [GO:1990841]; protein deacetylase activity [GO:0033558]; protein kinase binding [GO:0019901]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; SUMO transferase activity [GO:0019789]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to mechanical stimulus [GO:0071260]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of glycolytic process [GO:0045820]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; osteoblast development [GO:0002076]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of male mating behavior [GO:1902437]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deacetylation [GO:0006476]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein binding [GO:0043393]; regulation of skeletal muscle fiber development [GO:0048742]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to drug [GO:0042493]; response to interleukin-1 [GO:0070555]; skeletal system development [GO:0001501]		B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to mechanical stimulus [GO:0071260]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of glycolytic process [GO:0045820]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; osteoblast development [GO:0002076]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of male mating behavior [GO:1902437]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein binding [GO:0043393]; regulation of skeletal muscle fiber development [GO:0048742]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to drug [GO:0042493]; response to interleukin-1 [GO:0070555]; skeletal system development [GO:0001501]		A band [GO:0031672]; actomyosin [GO:0042641]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; neuromuscular junction [GO:0031594]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; Z disc [GO:0030018]		activating transcription factor binding [GO:0033613]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; potassium ion binding [GO:0030955]; promoter-specific chromatin binding [GO:1990841]; protein deacetylase activity [GO:0033558]; protein kinase binding [GO:0019901]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; SUMO transferase activity [GO:0019789]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]	
d4cc4c2_d5opfa___1			Firmicutes	Actinobacteria		hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]; carbohydrate metabolic process [GO:0005975]		carbohydrate metabolic process [GO:0005975]				hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; polysaccharide binding [GO:0030247]
d4cc5a__d3ba8a___1			Firmicutes	Firmicutes	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	DNA repair [GO:0006281]; DNA replication [GO:0006260]			DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]	DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]
d4cc6a__d1xk5a___1		Metazoa	Firmicutes	Chordata	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	cytosol [GO:0005829]; nuclear pore [GO:0005643]; nuclear import signal receptor activity [GO:0061608]; RNA cap binding [GO:0000339]; import into nucleus [GO:0051170]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]; spliceosomal snRNP assembly [GO:0000387]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	import into nucleus [GO:0051170]; protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]; spliceosomal snRNP assembly [GO:0000387]		cytosol [GO:0005829]; nuclear pore [GO:0005643]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]	nuclear import signal receptor activity [GO:0061608]; RNA cap binding [GO:0000339]
d4cc6a__d1zaua___1			Firmicutes	Actinobacteria	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; DNA ligase (NAD+) activity [GO:0003911]; magnesium ion binding [GO:0000287]; base-excision repair, DNA ligation [GO:0006288]; DNA ligation [GO:0006266]; DNA replication [GO:0006260]	DNA repair [GO:0006281]; DNA replication [GO:0006260]	base-excision repair, DNA ligation [GO:0006288]; DNA ligation [GO:0006266]; DNA replication [GO:0006260]		cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	DNA binding [GO:0003677]; DNA ligase (NAD+) activity [GO:0003911]; metal ion binding [GO:0046872]	DNA ligase (NAD+) activity [GO:0003911]; magnesium ion binding [GO:0000287]
d4ccpa__d2ghex1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	chloroplast [GO:0009507]; heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	chloroplast [GO:0009507]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	heme binding [GO:0020037]; L-ascorbate peroxidase activity [GO:0016688]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d4ccxa__d1igza1__1	Fungi	Metazoa	Ascomycota	Chordata	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]	cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]	cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	dioxygenase activity [GO:0051213]; drug binding [GO:0008144]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d4cd1a1_d5aqpc2__1	Metazoa	Metazoa	Chordata	Chordata	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adenosine-diphosphatase activity [GO:0043262]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]; apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	apoptotic process [GO:0006915]; cell surface receptor signaling pathway [GO:0007166]; chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of apoptotic process [GO:0043066]; regulation of cellular response to heat [GO:1900034]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]	adenosine-diphosphatase activity [GO:0043262]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]	adenyl-nucleotide exchange factor activity [GO:0000774]; chaperone binding [GO:0051087]; ubiquitin protein ligase binding [GO:0031625]
d4cd2a__d3f0xx___1	Fungi		Ascomycota		dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]		glycine biosynthetic process [GO:0006545]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]				dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]	
d4cd3a1_d5wfna2__1	Metazoa	Metazoa	Chordata	Arthropoda	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adenosine-diphosphatase activity [GO:0043262]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; identical protein binding [GO:0042802]; cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]; ATP binding [GO:0005524]; chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	cellular response to interferon-alpha [GO:0035457]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; protein homooligomerization [GO:0051260]; response to auditory stimulus [GO:0010996]	chromatin remodeling [GO:0006338]; maintenance of protein location in cell [GO:0032507]; mitotic cytokinesis [GO:0000281]; sperm individualization [GO:0007291]; tube formation [GO:0035148]	cell body [GO:0044297]; cell projection membrane [GO:0031253]; cell surface [GO:0009986]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	actin cytoskeleton [GO:0015629]; brahma complex [GO:0035060]; cell [GO:0005623]; cytoplasm [GO:0005737]; Ino80 complex [GO:0031011]	adenosine-diphosphatase activity [GO:0043262]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; identical protein binding [GO:0042802]	ATP binding [GO:0005524]
d4cdaa__d3l1ma___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d4cdgc1_d4edxl1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lateral element [GO:0000800]; nuclear chromosome [GO:0000228]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; replication fork [GO:0005657]; 3'-5' DNA helicase activity [GO:0043138]; 8-hydroxy-2'-deoxyguanosine DNA binding [GO:1905773]; annealing helicase activity [GO:0036310]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; DNA helicase activity [GO:0003678]; DNA-dependent ATPase activity [GO:0008094]; forked DNA-dependent helicase activity [GO:0061749]; four-way junction DNA binding [GO:0000400]; four-way junction helicase activity [GO:0009378]; G-quadruplex DNA binding [GO:0051880]; helicase activity [GO:0004386]; p53 binding [GO:0002039]; protein homodimerization activity [GO:0042803]; single-stranded DNA binding [GO:0003697]; telomeric D-loop binding [GO:0061821]; telomeric G-quadruplex DNA binding [GO:0061849]; Y-form DNA binding [GO:0000403]; zinc ion binding [GO:0008270]; cellular response to camptothecin [GO:0072757]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; mitotic G2 DNA damage checkpoint [GO:0007095]; negative regulation of cell division [GO:0051782]; negative regulation of DNA recombination [GO:0045910]; positive regulation of transcription, DNA-templated [GO:0045893]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of DNA-dependent DNA replication [GO:0090329]; regulation of signal transduction by p53 class mediator [GO:1901796]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to X-ray [GO:0010165]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomeric D-loop disassembly [GO:0061820]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]; cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	cellular response to camptothecin [GO:0072757]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; mitotic G2 DNA damage checkpoint [GO:0007095]; negative regulation of cell division [GO:0051782]; negative regulation of DNA recombination [GO:0045910]; positive regulation of transcription, DNA-templated [GO:0045893]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of DNA-dependent DNA replication [GO:0090329]; regulation of signal transduction by p53 class mediator [GO:1901796]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to X-ray [GO:0010165]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomeric D-loop disassembly [GO:0061820]	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPKK activity [GO:0000186]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nerve development [GO:0021675]; nerve growth factor processing [GO:0032455]; nerve growth factor signaling pathway [GO:0038180]; neuron apoptotic process [GO:0051402]; neuron projection morphogenesis [GO:0048812]; neurotrophin TRK receptor signaling pathway [GO:0048011]; peripheral nervous system development [GO:0007422]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axonogenesis [GO:0050772]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of neuron differentiation [GO:0045664]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	chromosome [GO:0005694]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; lateral element [GO:0000800]; nuclear chromosome [GO:0000228]; nuclear matrix [GO:0016363]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; replication fork [GO:0005657]	axon [GO:0030424]; cytoplasmic vesicle [GO:0031410]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome lumen [GO:0031904]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; synaptic vesicle [GO:0008021]	3'-5' DNA helicase activity [GO:0043138]; 8-hydroxy-2'-deoxyguanosine DNA binding [GO:1905773]; annealing helicase activity [GO:0036310]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; DNA-dependent ATPase activity [GO:0008094]; DNA helicase activity [GO:0003678]; forked DNA-dependent helicase activity [GO:0061749]; four-way junction DNA binding [GO:0000400]; four-way junction helicase activity [GO:0009378]; G-quadruplex DNA binding [GO:0051880]; helicase activity [GO:0004386]; p53 binding [GO:0002039]; protein homodimerization activity [GO:0042803]; single-stranded DNA binding [GO:0003697]; telomeric D-loop binding [GO:0061821]; telomeric G-quadruplex DNA binding [GO:0061849]; Y-form DNA binding [GO:0000403]; zinc ion binding [GO:0008270]	cysteine-type endopeptidase activator activity involved in apoptotic process [GO:0008656]; death receptor agonist activity [GO:0038177]; growth factor activity [GO:0008083]; lipid binding [GO:0008289]; metalloendopeptidase inhibitor activity [GO:0008191]; nerve growth factor receptor binding [GO:0005163]
d4cdha2_d3mrnb1__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4cdha2_d4kklc1__1	Metazoa		Chordata	Proteobacteria	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]; chloride transport [GO:0006821]; nitrate transport [GO:0015706]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	chloride transport [GO:0006821]; nitrate transport [GO:0015706]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	anion binding [GO:0043168]; chloride ion binding [GO:0031404]; identical protein binding [GO:0042802]; solute:proton antiporter activity [GO:0015299]; voltage-gated chloride channel activity [GO:0005247]
d4cdhb1_d4xp9l2__1	Metazoa	Metazoa	Chordata	Arthropoda	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	integral component of plasma membrane [GO:0005887]; neuron projection [GO:0043005]; neuronal cell body membrane [GO:0032809]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]; adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	adult locomotory behavior [GO:0008344]; circadian sleep/wake cycle [GO:0042745]; dopamine transport [GO:0015872]; dopamine uptake involved in synaptic transmission [GO:0051583]; norepinephrine transport [GO:0015874]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; sleep [GO:0030431]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	integral component of plasma membrane [GO:0005887]; neuronal cell body membrane [GO:0032809]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	cocaine binding [GO:0019811]; dopamine:sodium symporter activity [GO:0005330]; metal ion binding [GO:0046872]; neurotransmitter:sodium symporter activity [GO:0005328]
d4cdla__d3zg5a1__1			Proteobacteria	Firmicutes	steroid delta-isomerase activity [GO:0004769]; steroid metabolic process [GO:0008202]	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	steroid metabolic process [GO:0008202]	response to antibiotic [GO:0046677]		integral component of membrane [GO:0016021]	steroid delta-isomerase activity [GO:0004769]	penicillin binding [GO:0008658]
d4cdwc__d1d4m3___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d4cdxa__d2mev3___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleolus [GO:0044196]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d4cdxb__d1yc6g___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]; RNA binding [GO:0003723]; structural molecule activity [GO:0005198]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]		host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell endoplasmic reticulum [GO:0044165]; T=3 icosahedral viral capsid [GO:0039617]; viral nucleocapsid [GO:0019013]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	RNA binding [GO:0003723]; structural molecule activity [GO:0005198]
d4cdya__d2yl7a___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d4ce8d__d5mazc___1			Proteobacteria	Proteobacteria	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]; single-species biofilm formation [GO:0044010]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	single-species biofilm formation [GO:0044010]				carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]	carbohydrate binding [GO:0030246]; metal ion binding [GO:0046872]
d4celb__d4c4da___1	Fungi	Fungi	Ascomycota	Ascomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]
d4ceua__d1a5ka___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d4ceua__d4z42j___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d4ceva__d4cbya___1		Metazoa	Firmicutes	Chordata	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	A band [GO:0031672]; actomyosin [GO:0042641]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; neuromuscular junction [GO:0031594]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; Z disc [GO:0030018]; activating transcription factor binding [GO:0033613]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; potassium ion binding [GO:0030955]; promoter-specific chromatin binding [GO:1990841]; protein deacetylase activity [GO:0033558]; protein kinase binding [GO:0019901]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; SUMO transferase activity [GO:0019789]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to mechanical stimulus [GO:0071260]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of glycolytic process [GO:0045820]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; osteoblast development [GO:0002076]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of male mating behavior [GO:1902437]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deacetylation [GO:0006476]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein binding [GO:0043393]; regulation of skeletal muscle fiber development [GO:0048742]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to drug [GO:0042493]; response to interleukin-1 [GO:0070555]; skeletal system development [GO:0001501]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to mechanical stimulus [GO:0071260]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; inflammatory response [GO:0006954]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of glycolytic process [GO:0045820]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of pri-miRNA transcription by RNA polymerase II [GO:1902894]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; osteoblast development [GO:0002076]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of male mating behavior [GO:1902437]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein binding [GO:0043393]; regulation of skeletal muscle fiber development [GO:0048742]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to drug [GO:0042493]; response to interleukin-1 [GO:0070555]; skeletal system development [GO:0001501]		A band [GO:0031672]; actomyosin [GO:0042641]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; neuromuscular junction [GO:0031594]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptional repressor complex [GO:0017053]; Z disc [GO:0030018]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]	activating transcription factor binding [GO:0033613]; histone deacetylase activity [GO:0004407]; histone deacetylase binding [GO:0042826]; identical protein binding [GO:0042802]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; potassium ion binding [GO:0030955]; promoter-specific chromatin binding [GO:1990841]; protein deacetylase activity [GO:0033558]; protein kinase binding [GO:0019901]; repressing transcription factor binding [GO:0070491]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; SUMO transferase activity [GO:0019789]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d4cevb__d4gwca___1		Metazoa	Firmicutes	Chordata	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuron projection [GO:0043005]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]; arginase activity [GO:0004053]; manganese ion binding [GO:0030145]; adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	adaptive immune response [GO:0002250]; aging [GO:0007568]; arginine catabolic process [GO:0006527]; arginine catabolic process to ornithine [GO:0019547]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen biosynthetic process [GO:0032964]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; liver development [GO:0001889]; lung development [GO:0030324]; mammary gland involution [GO:0060056]; maternal process involved in female pregnancy [GO:0060135]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of T-helper 2 cell cytokine production [GO:2000552]; neutrophil degranulation [GO:0043312]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of neutrophil mediated killing of fungus [GO:0070965]; protein homotrimerization [GO:0070207]; regulation of L-arginine import [GO:0010963]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to cadmium ion [GO:0046686]; response to herbicide [GO:0009635]; response to manganese ion [GO:0010042]; response to methylmercury [GO:0051597]; response to selenium ion [GO:0010269]; response to vitamin A [GO:0033189]; response to vitamin E [GO:0033197]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]		azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; mitochondrial outer membrane [GO:0005741]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleus [GO:0005634]; specific granule lumen [GO:0035580]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]	arginase activity [GO:0004053]; manganese ion binding [GO:0030145]
d4cevc__d2pqpa___1			Firmicutes		arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]		arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]				arginase activity [GO:0004053]; metal ion binding [GO:0046872]	
d4ceve__d3c0ya1__1		Metazoa	Firmicutes	Chordata	arginase activity [GO:0004053]; metal ion binding [GO:0046872]; arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; 14-3-3 protein binding [GO:0071889]; activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; protein kinase binding [GO:0019901]; protein kinase C binding [GO:0005080]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]; cell-cell junction assembly [GO:0007043]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; vasculogenesis [GO:0001570]	arginine metabolic process [GO:0006525]; urea cycle [GO:0000050]	cell-cell junction assembly [GO:0007043]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; vasculogenesis [GO:0001570]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; histone deacetylase complex [GO:0000118]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	arginase activity [GO:0004053]; metal ion binding [GO:0046872]	14-3-3 protein binding [GO:0071889]; activating transcription factor binding [GO:0033613]; chromatin binding [GO:0003682]; metal ion binding [GO:0046872]; NAD-dependent histone deacetylase activity (H3-K14 specific) [GO:0032041]; protein kinase binding [GO:0019901]; protein kinase C binding [GO:0005080]; repressing transcription factor binding [GO:0070491]; transcription corepressor activity [GO:0003714]
d4cewa__d2r043___1					host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; structural molecule activity [GO:0005198]; DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; lysis of host organelle involved in viral entry into host cell [GO:0039664]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	host cell cytoplasmic vesicle membrane [GO:0044162]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198]
d4cexa__d1ejva___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d4cexb__d4epbb___1			Firmicutes	Proteobacteria	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]; nickel cation binding [GO:0016151]; urease activity [GO:0009039]; urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	urea catabolic process [GO:0043419]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]	nickel cation binding [GO:0016151]; urease activity [GO:0009039]
d4cfee2_d4frya___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; AMP-activated protein kinase activity [GO:0004679]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; cell cycle arrest [GO:0007050]; fatty acid biosynthetic process [GO:0006633]; macroautophagy [GO:0016236]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of signal transduction by p53 class mediator [GO:1901796]; signal transduction [GO:0007165]	nucleotide binding [GO:0000166]	cell cycle arrest [GO:0007050]; fatty acid biosynthetic process [GO:0006633]; macroautophagy [GO:0016236]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein heterooligomerization [GO:0051291]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of signal transduction by p53 class mediator [GO:1901796]; signal transduction [GO:0007165]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]		AMP-activated protein kinase activity [GO:0004679]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]	nucleotide binding [GO:0000166]
d4cfla__d5cuaa1__1	Metazoa	Metazoa	Chordata	Chordata	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; P-TEFb complex binding [GO:0106140]; p53 binding [GO:0002039]; RNA polymerase II C-terminal domain binding [GO:0099122]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; transcription regulator recruiting activity [GO:0001134]; cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	cellular response to DNA damage stimulus [GO:0006974]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of histone H3-K36 trimethylation [GO:2001255]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of inflammatory response [GO:0050727]; regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901407]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; viral process [GO:0016032]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	chromosome [GO:0005694]; condensed nuclear chromosome [GO:0000794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	nucleus [GO:0005634]	chromatin binding [GO:0003682]; enzyme binding [GO:0019899]; lysine-acetylated histone binding [GO:0070577]; p53 binding [GO:0002039]; P-TEFb complex binding [GO:0106140]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; RNA polymerase II C-terminal domain binding [GO:0099122]; transcription regulator recruiting activity [GO:0001134]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d4cfmb2_d1okvd1__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]
d4cfqb__d2k2aa___1	Metazoa	Metazoa	Chordata	Arthropoda	actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell leading edge [GO:0031252]; cell-cell adherens junction [GO:0005913]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]; actin binding [GO:0003779]; actin filament binding [GO:0051015]; actin-dependent ATPase activity [GO:0030898]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]; actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]	calcium ion binding [GO:0005509]	actin cytoskeleton reorganization [GO:0031532]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; cytokinetic process [GO:0032506]; establishment of meiotic spindle localization [GO:0051295]; establishment of T cell polarity [GO:0001768]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; leukocyte migration [GO:0050900]; lysosome localization [GO:0032418]; meiotic spindle organization [GO:0000212]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte differentiation [GO:0030224]; myoblast fusion [GO:0007520]; negative regulation of actin filament severing [GO:1903919]; phagocytosis, engulfment [GO:0006911]; plasma membrane repair [GO:0001778]; platelet aggregation [GO:0070527]; platelet formation [GO:0030220]; positive regulation of protein processing in phagocytic vesicle [GO:1903923]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; regulation of cell shape [GO:0008360]; regulation of plasma membrane repair [GO:1905684]; uropod organization [GO:0032796]		actin cytoskeleton [GO:0015629]; actomyosin [GO:0042641]; actomyosin contractile ring [GO:0005826]; brush border [GO:0005903]; cell [GO:0005623]; cell-cell adherens junction [GO:0005913]; cell leading edge [GO:0031252]; cleavage furrow [GO:0032154]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; immunological synapse [GO:0001772]; membrane [GO:0016020]; myosin II complex [GO:0016460]; myosin II filament [GO:0097513]; neuromuscular junction [GO:0031594]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991]; ruffle [GO:0001726]; spindle [GO:0005819]; stress fiber [GO:0001725]; uropod [GO:0001931]		actin binding [GO:0003779]; actin-dependent ATPase activity [GO:0030898]; actin filament binding [GO:0051015]; ADP binding [GO:0043531]; ATPase activity [GO:0016887]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; integrin binding [GO:0005178]; microfilament motor activity [GO:0000146]; motor activity [GO:0003774]; protein domain specific binding [GO:0019904]; protein homodimerization activity [GO:0042803]; protein membrane anchor [GO:0043495]; RNA binding [GO:0003723]	calcium ion binding [GO:0005509]
d4cfwb2_d1c9ba2__1	Metazoa	Metazoa	Chordata	Chordata	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]; anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcription factor TFIID complex [GO:0005669]; transcriptional preinitiation complex [GO:0097550]; acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; viral process [GO:0016032]	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cellular response to nitric oxide [GO:0071732]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; histone phosphorylation [GO:0016572]; meiotic cell cycle [GO:0051321]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-dependent DNA replication initiation [GO:0032298]; positive regulation of transcription, DNA-templated [GO:0045893]; potassium ion transport [GO:0006813]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of gene silencing [GO:0060968]; regulation of signal transduction by p53 class mediator [GO:1901796]	DNA-templated transcription, initiation [GO:0006352]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of core promoter binding [GO:1904798]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; protein acetylation [GO:0006473]; RNA polymerase II core complex assembly [GO:1990114]; RNA polymerase II preinitiation complex assembly [GO:0051123]; snRNA transcription by RNA polymerase II [GO:0042795]; transcriptional start site selection at RNA polymerase II promoter [GO:0001174]; transcription by RNA polymerase II [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	Cajal body [GO:0015030]; centrosome [GO:0005813]; chromosome, telomeric region [GO:0000781]; condensed chromosome [GO:0000793]; cyclin A1-CDK2 complex [GO:0097123]; cyclin A2-CDK2 complex [GO:0097124]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin E1-CDK2 complex [GO:0097134]; cyclin E2-CDK2 complex [GO:0097135]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome [GO:0005768]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; X chromosome [GO:0000805]; Y chromosome [GO:0000806]	chromosome [GO:0005694]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; RNA polymerase II transcription factor complex [GO:0090575]; transcriptional preinitiation complex [GO:0097550]; transcription factor TFIID complex [GO:0005669]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein kinase activity [GO:0097472]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; magnesium ion binding [GO:0000287]; protein domain specific binding [GO:0019904]; protein serine/threonine kinase activity [GO:0004674]	acetyltransferase activity [GO:0016407]; core promoter binding [GO:0001047]; histone acetyltransferase activity [GO:0004402]; promoter-specific chromatin binding [GO:1990841]; RNA polymerase II complex binding [GO:0000993]; RNA polymerase II complex recruiting activity [GO:0001139]; RNA polymerase II core promoter sequence-specific DNA binding [GO:0000979]; RNA polymerase II general transcription initiation factor activity [GO:0016251]; TBP-class protein binding [GO:0017025]; thyroid hormone receptor binding [GO:0046966]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]
d4cfza__d3i2yx___1		Fungi	Firmicutes	Ascomycota	extracellular region [GO:0005576]; metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]; sporulation resulting in formation of a cellular spore [GO:0030435]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	sporulation resulting in formation of a cellular spore [GO:0030435]		extracellular region [GO:0005576]		metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]	metal ion binding [GO:0046872]; serine-type endopeptidase activity [GO:0004252]
d4cg3a1_d5jzsa___1			Actinobacteria	Actinobacteria	cutinase activity [GO:0050525]	cell wall [GO:0005618]; plasma membrane [GO:0005886]; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]; aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]		aromatic compound catabolic process [GO:0019439]; growth of symbiont in host [GO:0044117]; lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]		cell wall [GO:0005618]; plasma membrane [GO:0005886]	cutinase activity [GO:0050525]	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity [GO:0018774]; 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity [GO:0102296]; 4,9-DSHA hydrolase activity [GO:0034820]
d4cgeb__d2fbdb___1		Metazoa	Actinobacteria	Arthropoda	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	lysozyme activity [GO:0003796]; metabolic process [GO:0008152]	negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	metabolic process [GO:0008152]	extracellular region [GO:0005576]		hydrolase activity [GO:0016787]	lysozyme activity [GO:0003796]
d4cgec__d4yf2a1__1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	acrosomal matrix [GO:0043159]; acrosomal membrane [GO:0002080]; acrosomal vesicle [GO:0001669]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; secretory granule [GO:0030141]; lysozyme activity [GO:0003796]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; sperm-egg recognition [GO:0035036]	negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; sperm-egg recognition [GO:0035036]	extracellular region [GO:0005576]	acrosomal matrix [GO:0043159]; acrosomal membrane [GO:0002080]; acrosomal vesicle [GO:0001669]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; secretory granule [GO:0030141]	hydrolase activity [GO:0016787]	lysozyme activity [GO:0003796]
d4cgee__d3hbha___1		Viridiplantae	Actinobacteria	Streptophyta	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; chitin catabolic process [GO:0006032]	extracellular region [GO:0005576]		hydrolase activity [GO:0016787]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d4cgef__d2fbda___1		Metazoa	Actinobacteria	Arthropoda	extracellular region [GO:0005576]; hydrolase activity [GO:0016787]; negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	lysozyme activity [GO:0003796]; metabolic process [GO:0008152]	negative regulation of gene expression [GO:0010629]; pathogenesis [GO:0009405]; positive regulation of gene expression [GO:0010628]; positive regulation of growth rate [GO:0040010]	metabolic process [GO:0008152]	extracellular region [GO:0005576]		hydrolase activity [GO:0016787]	lysozyme activity [GO:0003796]
d4cgta1_d1ehna1__1			Firmicutes	Proteobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	chitin binding [GO:0008061]; chitinase activity [GO:0004568]; chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	carbohydrate metabolic process [GO:0005975]	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	extracellular region [GO:0005576]		cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d4cgta1_d5vg1b___1			Firmicutes	Actinobacteria	extracellular region [GO:0005576]; cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]; carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]; chitin binding [GO:0008061]; chitinase activity [GO:0004568]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cyclomaltodextrin glucanotransferase activity [GO:0043895]; metal ion binding [GO:0046872]; starch binding [GO:2001070]	carbohydrate binding [GO:0030246]; chitinase activity [GO:0004568]; chitin binding [GO:0008061]
d4ch0s1_d2lcwa___1	Metazoa	Metazoa	Nematoda (roundworms)	Chordata	nuclear speck [GO:0016607]; ribonucleoprotein complex [GO:1990904]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; pre-mRNA intronic binding [GO:0097157]; single-stranded RNA binding [GO:0003727]; alternative mRNA splicing, via spliceosome [GO:0000380]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of locomotion [GO:0040012]	dendritic spine head [GO:0044327]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]; chromatin binding [GO:0003682]; DNA binding [GO:0003677]; estrogen receptor binding [GO:0030331]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; myosin V binding [GO:0031489]; retinoid X receptor binding [GO:0046965]; RNA binding [GO:0003723]; thyroid hormone receptor binding [GO:0046966]; transcription coactivator activity [GO:0003713]; cellular response to calcium ion [GO:0071277]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein homooligomerization [GO:0051260]; regulation of RNA splicing [GO:0043484]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]	alternative mRNA splicing, via spliceosome [GO:0000380]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of locomotion [GO:0040012]	cellular response to calcium ion [GO:0071277]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; protein homooligomerization [GO:0051260]; regulation of RNA splicing [GO:0043484]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA splicing [GO:0008380]	nuclear speck [GO:0016607]; ribonucleoprotein complex [GO:1990904]	dendritic spine head [GO:0044327]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; polysome [GO:0005844]	mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; pre-mRNA intronic binding [GO:0097157]; single-stranded RNA binding [GO:0003727]	chromatin binding [GO:0003682]; DNA binding [GO:0003677]; estrogen receptor binding [GO:0030331]; identical protein binding [GO:0042802]; ionotropic glutamate receptor binding [GO:0035255]; metal ion binding [GO:0046872]; mRNA 3'-UTR binding [GO:0003730]; myosin V binding [GO:0031489]; retinoid X receptor binding [GO:0046965]; RNA binding [GO:0003723]; thyroid hormone receptor binding [GO:0046966]; transcription coactivator activity [GO:0003713]
d4chsa2_d4g9hb2__1	Viridiplantae		Streptophyta	Proteobacteria	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	transferase activity [GO:0016740]	glutathione metabolic process [GO:0006749]		cytoplasm [GO:0005737]		glutathione transferase activity [GO:0004364]	transferase activity [GO:0016740]
d4chsb1_d5a5kl1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]; camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]; auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	glutathione metabolic process [GO:0006749]	auxin-activated signaling pathway [GO:0009734]; defense response to bacterium [GO:0042742]; glutathione metabolic process [GO:0006749]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to oomycetes [GO:0002239]; response to zinc ion [GO:0010043]; toxin catabolic process [GO:0009407]	cytoplasm [GO:0005737]	apoplast [GO:0048046]; chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773]	glutathione transferase activity [GO:0004364]	camalexin binding [GO:2001147]; glutathione binding [GO:0043295]; glutathione transferase activity [GO:0004364]; peroxidase activity [GO:0004601]; protein domain specific binding [GO:0019904]; quercitrin binding [GO:2001227]
d4chsb2_d1tdib2__1	Viridiplantae	Metazoa	Streptophyta	Chordata	cytoplasm [GO:0005737]; glutathione transferase activity [GO:0004364]; glutathione metabolic process [GO:0006749]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]; glutathione transferase activity [GO:0004364]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	glutathione metabolic process [GO:0006749]	glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; xenobiotic metabolic process [GO:0006805]	cytoplasm [GO:0005737]	cytosol [GO:0005829]; extracellular exosome [GO:0070062]	glutathione transferase activity [GO:0004364]	glutathione transferase activity [GO:0004364]
d4ci6a2_d3r6md2__1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]	cytoplasm [GO:0005737]; tRNA threonylcarbamoyladenosine modification [GO:0002949]		tRNA threonylcarbamoyladenosine modification [GO:0002949]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]	
d4cipa__d5gyre___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d4cjma__d2p39a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]; growth factor activity [GO:0008083]; type 1 fibroblast growth factor receptor binding [GO:0005105]; type 2 fibroblast growth factor receptor binding [GO:0005111]; anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte development [GO:0002063]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor signaling pathway [GO:0008543]; intramembranous ossification [GO:0001957]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; signal transduction [GO:0007165]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; growth factor activity [GO:0008083]; type 1 fibroblast growth factor receptor binding [GO:0005105]; cell differentiation [GO:0030154]; cellular phosphate ion homeostasis [GO:0030643]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-6 [GO:0071354]; cellular response to leptin stimulus [GO:0044320]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to vitamin D [GO:0071305]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of bone mineralization [GO:0030502]; negative regulation of hormone secretion [GO:0046888]; negative regulation of osteoblast differentiation [GO:0045668]; phosphate ion homeostasis [GO:0055062]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vitamin D 24-hydroxylase activity [GO:0010980]; post-translational protein modification [GO:0043687]; regulation of phosphate transport [GO:0010966]; response to magnesium ion [GO:0032026]; response to sodium phosphate [GO:1904383]; vitamin D catabolic process [GO:0042369]	anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; cell-cell signaling [GO:0007267]; chondrocyte development [GO:0002063]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor signaling pathway [GO:0008543]; intramembranous ossification [GO:0001957]; lung development [GO:0030324]; MAPK cascade [GO:0000165]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; signal transduction [GO:0007165]	cell differentiation [GO:0030154]; cellular phosphate ion homeostasis [GO:0030643]; cellular protein metabolic process [GO:0044267]; cellular response to interleukin-6 [GO:0071354]; cellular response to leptin stimulus [GO:0044320]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to vitamin D [GO:0071305]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of bone mineralization [GO:0030502]; negative regulation of hormone secretion [GO:0046888]; negative regulation of osteoblast differentiation [GO:0045668]; phosphate ion homeostasis [GO:0055062]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vitamin D 24-hydroxylase activity [GO:0010980]; post-translational protein modification [GO:0043687]; regulation of phosphate transport [GO:0010966]; response to magnesium ion [GO:0032026]; response to sodium phosphate [GO:1904383]; vitamin D catabolic process [GO:0042369]	extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleolus [GO:0005730]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]	growth factor activity [GO:0008083]; type 1 fibroblast growth factor receptor binding [GO:0005105]; type 2 fibroblast growth factor receptor binding [GO:0005111]	growth factor activity [GO:0008083]; type 1 fibroblast growth factor receptor binding [GO:0005105]
d4cjna1_d4xb5a2__1			Firmicutes	Cyanobacteria	penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; response to antibiotic [GO:0046677]	phycobilisome [GO:0030089]; chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]; light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]	response to antibiotic [GO:0046677]	light absorption [GO:0016037]; protein-chromophore linkage [GO:0018298]		phycobilisome [GO:0030089]	penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]	chloride ion binding [GO:0031404]; photoreceptor activity [GO:0009881]
d4cjnb1_d5wicd___1			Firmicutes	Proteobacteria	penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]; response to antibiotic [GO:0046677]	integral component of membrane [GO:0016021]; protein secretion by the type IV secretion system [GO:0030255]	response to antibiotic [GO:0046677]	protein secretion by the type IV secretion system [GO:0030255]		integral component of membrane [GO:0016021]	penicillin binding [GO:0008658]; serine-type D-Ala-D-Ala carboxypeptidase activity [GO:0009002]	
d4cjoa__d3m4bc___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d4cjoa__d5gyri___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d4ckob4_d4ed5b1__1		Metazoa		Chordata		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]; AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]; 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]		3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; negative regulation of gene silencing by miRNA [GO:0060965]; positive regulation of translation [GO:0045727]; protein homooligomerization [GO:0051260]; regulation of mRNA stability [GO:0043488]; regulation of stem cell population maintenance [GO:2000036]		cytoplasm [GO:0005737]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; postsynapse [GO:0098794]; ribonucleoprotein complex [GO:1990904]		AU-rich element binding [GO:0017091]; double-stranded RNA binding [GO:0003725]; miRNA binding [GO:0035198]; mRNA 3'-UTR AU-rich region binding [GO:0035925]; mRNA 3'-UTR binding [GO:0003730]; mRNA binding [GO:0003729]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; RNA binding [GO:0003723]
d4ckoe4_d5ddqd___1		Metazoa		Chordata		nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]; mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]		mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363]		nucleoplasm [GO:0005654]; spliceosomal complex [GO:0005681]; U1 snRNP [GO:0005685]		identical protein binding [GO:0042802]; RNA binding [GO:0003723]; U1 snRNA binding [GO:0030619]; U1 snRNP binding [GO:1990446]
d4ckuf__d4y4ea___1		Fungi	Apicomplexa	Ascomycota	vacuole [GO:0005773]; aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]			vacuole [GO:0005773]		aspartic-type endopeptidase activity [GO:0004190]	aspartic-type endopeptidase activity [GO:0004190]
d4cl0a__d4b6sa___1			Actinobacteria	Proteobacteria	cytosol [GO:0005829]; 3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	3-dehydroquinate dehydratase activity [GO:0003855]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	cytosol [GO:0005829]		3-dehydroquinate dehydratase activity [GO:0003855]	3-dehydroquinate dehydratase activity [GO:0003855]
d4cl3a2_d5kvvb2__1			Chloroflexi	Actinobacteria	cytoplasm [GO:0005737]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; L-malate dehydrogenase activity [GO:0030060]; carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]; tricarboxylic acid cycle [GO:0006099]	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099]	cytoplasm [GO:0005737]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	L-malate dehydrogenase activity [GO:0030060]	L-malate dehydrogenase activity [GO:0030060]
d4cl7b__d3cfkg1__1	Metazoa	Metazoa	Chordata	Chordata	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor binding [GO:0038085]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; negative regulation of vascular endothelial cell proliferation [GO:1905563]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	actin cytoskeleton [GO:0015629]; endosome [GO:0005768]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	ATP binding [GO:0005524]; growth factor binding [GO:0019838]; placental growth factor-activated receptor activity [GO:0036332]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; vascular endothelial growth factor-activated receptor activity [GO:0005021]; vascular endothelial growth factor binding [GO:0038085]; VEGF-A-activated receptor activity [GO:0036326]; VEGF-B-activated receptor activity [GO:0036327]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4cmhc1_d1b6db2__1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]		apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]		basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]		identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	
d4cmhc1_d3q5yb1__1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]		apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]		basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]		identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	
d4cmhc2_d4xbpd1__1	Metazoa		Chordata		basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]; apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]		apoptotic signaling pathway [GO:0097190]; artery smooth muscle contraction [GO:0014824]; B cell receptor signaling pathway [GO:0050853]; female pregnancy [GO:0007565]; long-term synaptic depression [GO:0060292]; NAD metabolic process [GO:0019674]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell growth [GO:0030307]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of vasoconstriction [GO:0045907]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hydroperoxide [GO:0033194]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]		basolateral plasma membrane [GO:0016323]; cell [GO:0005623]; cell surface [GO:0009986]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]		identical protein binding [GO:0042802]; NAD(P)+ nucleosidase activity [GO:0050135]; NAD+ nucleosidase activity [GO:0003953]; NAD+ nucleotidase, cyclic ADP-ribose generating [GO:0061809]; phosphorus-oxygen lyase activity [GO:0016849]; transferase activity [GO:0016740]	
d4cmya__d1z6ou___1		Metazoa	Chlorobi	Arthropoda	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4cmya__d3dhza___1			Chlorobi	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d4cmyb__d5d8rg___1			Chlorobi	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4cmyd__d4m1ia1__1			Chlorobi	Chlamydiae	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]	ribonucleoside-diphosphate reductase complex [GO:0005971]	ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d4cmye__d5d8se___1			Chlorobi	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4cmyl__d4toep___1			Chlorobi	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4cmym__d1f33d___1			Chlorobi	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; chromosome condensation [GO:0030261]; response to starvation [GO:0042594]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; identical protein binding [GO:0042802]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d4cmyn__d2fzfb___1			Chlorobi	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d4cmyo__d3is8c___1			Chlorobi	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4cmyo__d3qd8d1__1			Chlorobi	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; response to hypoxia [GO:0001666]; response to nitrosative stress [GO:0051409]; siderophore-dependent iron import into cell [GO:0033214]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cell wall [GO:0005618]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; plasma membrane [GO:0005886]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d4cmyq__d1vela___1			Chlorobi	Actinobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]; nucleoid [GO:0009295]	ferric iron binding [GO:0008199]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d4cmyr__d3rnba___1			Chlorobi	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d4cmyt__d2x17p___1			Chlorobi	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]
d4cmyv__d1tjob___1			Chlorobi	Euryarchaeota	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]; cytoplasm [GO:0005737]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d4cmyv__d5d8ob___1			Chlorobi	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytoplasm [GO:0005737]	cell [GO:0005623]	ferric iron binding [GO:0008199]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4cmyx__d1mhzd___1			Chlorobi	Proteobacteria	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	methane monooxygenase activity [GO:0015049]; methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	methane metabolic process [GO:0015947]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]; cytoplasm [GO:0005737]		ferric iron binding [GO:0008199]	methane monooxygenase activity [GO:0015049]
d4cnib2_d1i7za1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4cnib2_d4u6hd2__1	Metazoa		Chordata		cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]	integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]	
d4cnil2_d3ubxl1__1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]; cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]; acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	acute-phase response [GO:0006953]; cellular protein metabolic process [GO:0044267]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; endocrine pancreas development [GO:0031018]; glucagon secretion [GO:0070091]; hepatic immune response [GO:0002384]; humoral immune response [GO:0006959]; inflammatory response [GO:0006954]; interleukin-6-mediated signaling pathway [GO:0070102]; monocyte chemotaxis [GO:0002548]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine biosynthetic process [GO:0045079]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of lipid storage [GO:0010888]; negative regulation of neurogenesis [GO:0050768]; neuron cellular homeostasis [GO:0070050]; neuron projection development [GO:0031175]; neutrophil apoptotic process [GO:0001781]; neutrophil mediated immunity [GO:0002446]; platelet activation [GO:0030168]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell activation [GO:0050871]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chemokine production [GO:0032722]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-17 biosynthetic process [GO:0045380]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuroinflammatory response [GO:0150078]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type B pancreatic cell apoptotic process [GO:2000676]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; positive regulation of vascular endothelial growth factor production [GO:0010575]; post-translational protein modification [GO:0043687]; regulation of angiogenesis [GO:0045765]; regulation of astrocyte activation [GO:0061888]; regulation of maintenance of permeability of blood-brain barrier [GO:1905603]; regulation of microglial cell activation [GO:1903978]; regulation of neuroinflammatory response [GO:0150077]; regulation of vascular endothelial growth factor production [GO:0010574]; response to glucocorticoid [GO:0051384]; response to peptidoglycan [GO:0032494]; T-helper 17 cell lineage commitment [GO:0072540]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; interleukin-6 receptor complex [GO:0005896]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	cytokine activity [GO:0005125]; growth factor activity [GO:0008083]; interleukin-6 receptor binding [GO:0005138]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4cnrd__d4kp8b___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]; chloride ion homeostasis [GO:0055064]	angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	bicarbonate transport [GO:0015701]; chloride ion homeostasis [GO:0055064]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d4cnva__d4qsjb___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; myelin sheath [GO:0043209]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; bicarbonate transport [GO:0015701]	angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	bicarbonate transport [GO:0015701]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; myelin sheath [GO:0043209]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]
d4cnxa__d3jxgc___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]; angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; toxin transport [GO:1901998]	angiotensin-activated signaling pathway [GO:0038166]; positive regulation of dipeptide transmembrane transport [GO:2001150]; regulation of anion transport [GO:0044070]; regulation of intracellular pH [GO:0051453]	negative regulation of epithelial cell migration [GO:0010633]; negative regulation of neuron projection development [GO:0010977]; protein dephosphorylation [GO:0006470]; toxin transport [GO:1901998]	cell [GO:0005623]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; integral component of membrane [GO:0016021]	carbonate dehydratase activity [GO:0004089]; zinc ion binding [GO:0008270]	identical protein binding [GO:0042802]; protein tyrosine phosphatase activity [GO:0004725]
d4co1b__d3ah6d___1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; metal ion binding [GO:0046872]; protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]	regulation of nitrogen utilization [GO:0006808]	protein homooligomerization [GO:0051260]; response to copper ion [GO:0046688]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]	copper ion binding [GO:0005507]; metal ion binding [GO:0046872]
d4co2a__d2xzwc1__1			Proteobacteria	Cyanobacteria	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]; regulation of nitrogen utilization [GO:0006808]	regulation of nitrogen utilization [GO:0006808]	regulation of nitrogen utilization [GO:0006808]			ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]	enzyme regulator activity [GO:0030234]; identical protein binding [GO:0042802]; nucleotide binding [GO:0000166]
d4co2a__d3gsdi___1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]	cytoplasm [GO:0005737]; copper ion binding [GO:0005507]; response to metal ion [GO:0010038]	regulation of nitrogen utilization [GO:0006808]	response to metal ion [GO:0010038]		cytoplasm [GO:0005737]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]	copper ion binding [GO:0005507]
d4co2b__d2rd5c___1		Viridiplantae	Proteobacteria	Streptophyta	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]; regulation of nitrogen utilization [GO:0006808]	chloroplast [GO:0009507]; chloroplast thylakoid [GO:0009534]; cytosol [GO:0005829]; plastid [GO:0009536]; acetylglutamate kinase regulator activity [GO:0010307]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; anthocyanin-containing compound biosynthetic process [GO:0009718]; nitrogen compound metabolic process [GO:0006807]; regulation of arginine biosynthetic process via ornithine [GO:2000013]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of nitrogen utilization [GO:0006808]; response to light stimulus [GO:0009416]; response to sucrose [GO:0009744]	regulation of nitrogen utilization [GO:0006808]	anthocyanin-containing compound biosynthetic process [GO:0009718]; nitrogen compound metabolic process [GO:0006807]; regulation of arginine biosynthetic process via ornithine [GO:2000013]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of nitrogen utilization [GO:0006808]; response to light stimulus [GO:0009416]; response to sucrose [GO:0009744]		chloroplast [GO:0009507]; chloroplast thylakoid [GO:0009534]; cytosol [GO:0005829]; plastid [GO:0009536]	ATP binding [GO:0005524]; enzyme regulator activity [GO:0030234]	acetylglutamate kinase regulator activity [GO:0010307]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]
d4co9b__d1r61b___1			Firmicutes	Firmicutes	arylformamidase activity [GO:0004061]; formamidase activity [GO:0004328]; zinc ion binding [GO:0008270]; anthranilate metabolic process [GO:0043420]; tryptophan catabolic process to kynurenine [GO:0019441]	arylformamidase activity [GO:0004061]; metal ion binding [GO:0046872]; tryptophan catabolic process to kynurenine [GO:0019441]	anthranilate metabolic process [GO:0043420]; tryptophan catabolic process to kynurenine [GO:0019441]	tryptophan catabolic process to kynurenine [GO:0019441]			arylformamidase activity [GO:0004061]; formamidase activity [GO:0004328]; zinc ion binding [GO:0008270]	arylformamidase activity [GO:0004061]; metal ion binding [GO:0046872]
d4co9c__d1r61a___1			Firmicutes	Firmicutes	arylformamidase activity [GO:0004061]; formamidase activity [GO:0004328]; zinc ion binding [GO:0008270]; anthranilate metabolic process [GO:0043420]; tryptophan catabolic process to kynurenine [GO:0019441]	arylformamidase activity [GO:0004061]; metal ion binding [GO:0046872]; tryptophan catabolic process to kynurenine [GO:0019441]	anthranilate metabolic process [GO:0043420]; tryptophan catabolic process to kynurenine [GO:0019441]	tryptophan catabolic process to kynurenine [GO:0019441]			arylformamidase activity [GO:0004061]; formamidase activity [GO:0004328]; zinc ion binding [GO:0008270]	arylformamidase activity [GO:0004061]; metal ion binding [GO:0046872]
d4cocc__d3p05a2__1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; identical protein binding [GO:0042802]; lipid binding [GO:0008289]; magnesium ion binding [GO:0000287]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; protein homodimerization activity [GO:0042803]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d4codf__d1u2db1__1			Actinobacteria	Proteobacteria	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	NAD binding [GO:0051287]; NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]; NADPH regeneration [GO:0006740]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	NADPH regeneration [GO:0006740]	cell wall [GO:0005618]; plasma membrane [GO:0005886]		enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	NAD(P)+ transhydrogenase (AB-specific) activity [GO:0008750]; NAD(P)+ transhydrogenase (B-specific) activity [GO:0003957]; NAD+ binding [GO:0070403]; NAD binding [GO:0051287]; NADH binding [GO:0070404]; protein dimerization activity [GO:0046983]
d4codf__d3g49c___1		Metazoa	Actinobacteria	Chordata	cell wall [GO:0005618]; plasma membrane [GO:0005886]; enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]; fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; 11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]; lung development [GO:0030324]; steroid metabolic process [GO:0008202]	fatty acid elongation [GO:0030497]; mycolic acid biosynthetic process [GO:0071768]; response to antibiotic [GO:0046677]	lung development [GO:0030324]; steroid metabolic process [GO:0008202]	cell wall [GO:0005618]; plasma membrane [GO:0005886]	endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]	enoyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0004318]; enoyl-[acyl-carrier-protein] reductase activity [GO:0016631]; fatty acid binding [GO:0005504]; NAD+ binding [GO:0070403]	11-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO:0070524]
d4coga__d4coab___1			Proteobacteria		arylformamidase activity [GO:0004061]; formamidase activity [GO:0004328]; zinc ion binding [GO:0008270]; anthranilate metabolic process [GO:0043420]; tryptophan catabolic process to kynurenine [GO:0019441]		anthranilate metabolic process [GO:0043420]; tryptophan catabolic process to kynurenine [GO:0019441]				arylformamidase activity [GO:0004061]; formamidase activity [GO:0004328]; zinc ion binding [GO:0008270]	
d4cp3a1_d1dsxc___1	Metazoa	Metazoa	Chordata	Chordata	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; intronic transcription regulatory region sequence-specific DNA binding [GO:0001161]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]; actin cytoskeleton organization [GO:0030036]; B cell differentiation [GO:0030183]; cell morphogenesis [GO:0000902]; cellular response to DNA damage stimulus [GO:0006974]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte development [GO:0048821]; germinal center formation [GO:0002467]; inflammatory response [GO:0006954]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cellular senescence [GO:2000773]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mitotic cell cycle DNA replication [GO:1903464]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular component movement [GO:0051272]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of germinal center formation [GO:0002634]; regulation of GTPase activity [GO:0043087]; regulation of immune response [GO:0050776]; regulation of inflammatory response [GO:0050727]; regulation of memory T cell differentiation [GO:0043380]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; type 2 immune response [GO:0042092]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]; delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	actin cytoskeleton organization [GO:0030036]; B cell differentiation [GO:0030183]; cell morphogenesis [GO:0000902]; cellular response to DNA damage stimulus [GO:0006974]; cytokine-mediated signaling pathway [GO:0019221]; erythrocyte development [GO:0048821]; germinal center formation [GO:0002467]; inflammatory response [GO:0006954]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cell growth [GO:0030308]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular senescence [GO:2000773]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mitotic cell cycle DNA replication [GO:1903464]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cellular component movement [GO:0051272]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of regulatory T cell differentiation [GO:0045591]; protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981]; regulation of cell population proliferation [GO:0042127]; regulation of germinal center formation [GO:0002634]; regulation of GTPase activity [GO:0043087]; regulation of immune response [GO:0050776]; regulation of inflammatory response [GO:0050727]; regulation of memory T cell differentiation [GO:0043380]; Rho protein signal transduction [GO:0007266]; spermatogenesis [GO:0007283]; type 2 immune response [GO:0042092]	neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein complex oligomerization [GO:0051259]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233]	Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	axon [GO:0030424]; axon terminus [GO:0043679]; calyx of Held [GO:0044305]; dendrite [GO:0030425]; endoplasmic reticulum membrane [GO:0005789]; endosome [GO:0005768]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; integral component of presynaptic membrane [GO:0099056]; juxtaparanode region of axon [GO:0044224]; lamellipodium [GO:0030027]; lamellipodium membrane [GO:0031258]; neuronal cell body membrane [GO:0032809]; paranodal junction [GO:0033010]; perikaryon [GO:0043204]; potassium channel complex [GO:0034705]; voltage-gated potassium channel complex [GO:0008076]	chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; identical protein binding [GO:0042802]; intronic transcription regulatory region sequence-specific DNA binding [GO:0001161]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; sequence-specific DNA binding [GO:0043565]	delayed rectifier potassium channel activity [GO:0005251]; kinesin binding [GO:0019894]; outward rectifier potassium channel activity [GO:0015271]; voltage-gated potassium channel activity [GO:0005249]
d4cp4a__d4jbta___1			Proteobacteria	Actinobacteria	cytoplasm [GO:0005737]; camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]; (+)-camphor catabolic process [GO:0019383]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]	(+)-camphor catabolic process [GO:0019383]		cytoplasm [GO:0005737]		camphor 5-monooxygenase activity [GO:0018683]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	heme binding [GO:0020037]; iron ion binding [GO:0005506]; monooxygenase activity [GO:0004497]; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705]
d4cp5a__d3gpab1__1					cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]		ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d4cp5b__d5v6dd___1				Proteobacteria	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d4cp5c__d4di6a1__1				Spirochaetes	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytosol [GO:0005829]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytosol [GO:0005829]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d4cp5d__d1wkja1__1				Deinococcus-Thermus	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	actin cytoskeleton organization [GO:0030036]; asexual reproduction [GO:0019954]; CTP biosynthetic process [GO:0006241]; dGDP phosphorylation [GO:0006186]; dGTP biosynthetic process from dGDP [GO:0006187]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP biosynthetic process [GO:0006183]; negative regulation of exocytosis [GO:0045920]; negative regulation of phagocytosis [GO:0050765]; negative regulation of pinocytosis [GO:0048550]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; response to bacterium [GO:0009617]; translational elongation [GO:0006414]; UTP biosynthetic process [GO:0006228]	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886]; ribosome [GO:0005840]; secretory granule [GO:0030141]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; nucleoside diphosphate kinase activity [GO:0004550]
d4cp7a__d4l1aa___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; RNA-directed DNA polymerase activity [GO:0003964]
d4cp7b__d1t3rb___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]
d4cp7b__d4y3fa___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d4cpaa__d2pj6a___1	Metazoa	Metazoa	Chordata	Chordata	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	extracellular space [GO:0005615]; metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]; proteolysis [GO:0006508]	proteolysis [GO:0006508]	proteolysis [GO:0006508]	extracellular space [GO:0005615]	extracellular space [GO:0005615]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]	metallocarboxypeptidase activity [GO:0004181]; zinc ion binding [GO:0008270]
d4cpea__d1swkc___1			Actinobacteria	Actinobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	extracellular region [GO:0005576]; biotin binding [GO:0009374]			extracellular region [GO:0005576]	extracellular region [GO:0005576]	biotin binding [GO:0009374]	biotin binding [GO:0009374]
d4cpeb__d4bj8l___1		Metazoa	Actinobacteria	Chordata	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d4cpid__d3szig1__1			Actinobacteria	Proteobacteria	extracellular region [GO:0005576]; biotin binding [GO:0009374]	biotin binding [GO:0009374]			extracellular region [GO:0005576]		biotin binding [GO:0009374]	biotin binding [GO:0009374]
d4cpka1_d2b1xf___1			Firmicutes	Actinobacteria	integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]; cellular metabolic process [GO:0044237]	response to antibiotic [GO:0046677]	cellular metabolic process [GO:0044237]	integral component of membrane [GO:0016021]		penicillin binding [GO:0008658]	2 iron, 2 sulfur cluster binding [GO:0051537]; dioxygenase activity [GO:0051213]; iron ion binding [GO:0005506]
d4cpkb1_d1tuha___1			Firmicutes		integral component of membrane [GO:0016021]; penicillin binding [GO:0008658]; response to antibiotic [GO:0046677]		response to antibiotic [GO:0046677]		integral component of membrane [GO:0016021]		penicillin binding [GO:0008658]	
d4cpma__d3b7eb___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d4cpnb__d4wa5a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d4cpob__d2c4la___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d4cpqa__d5dr0a___1		Fungi		Ascomycota	host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d4cpta__d2ceja___1					host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]; aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]	aspartic-type endopeptidase activity [GO:0004190]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732]		host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036]		aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270]	aspartic-type endopeptidase activity [GO:0004190]
d4cpza__d3ticc___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d4cpzb__d3ti6b___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d4cpzc__d4b7qd___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d4cpze__d4gezk___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d4cpzf__d1inva___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]; exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	carbohydrate metabolic process [GO:0005975]	carbohydrate metabolic process [GO:0005975]; viral budding from plasma membrane [GO:0046761]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; virion membrane [GO:0055036]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; metal ion binding [GO:0046872]
d4cq1b2_d1o0pa___1	Metazoa	Metazoa	Chordata	Chordata	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribosome [GO:0005840]; spliceosomal complex [GO:0005681]; identical protein binding [GO:0042802]; pre-mRNA branch point binding [GO:0045131]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270]; Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nuclear body organization [GO:0030575]; regulation of steroid biosynthetic process [GO:0050810]; spliceosomal complex assembly [GO:0000245]	cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nuclear body organization [GO:0030575]; regulation of steroid biosynthetic process [GO:0050810]; spliceosomal complex assembly [GO:0000245]	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]	nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribosome [GO:0005840]; spliceosomal complex [GO:0005681]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	identical protein binding [GO:0042802]; pre-mRNA branch point binding [GO:0045131]; RNA binding [GO:0003723]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270]
d4cq1g2_d1l3ka1__1	Metazoa	Metazoa	Chordata	Chordata	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]; G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]; cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	cerebellum development [GO:0021549]; mRNA splice site selection [GO:0006376]; negative regulation of RNA splicing [GO:0033119]; regulation of neural precursor cell proliferation [GO:2000177]; spinal cord development [GO:0021510]	cellular response to glucose starvation [GO:0042149]; cellular response to sodium arsenite [GO:1903936]; fibroblast growth factor receptor signaling pathway [GO:0008543]; import into nucleus [GO:0051170]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of telomere maintenance via telomerase [GO:0032211]; nuclear export [GO:0051168]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; viral process [GO:0016032]	growth cone [GO:0030426]; neuronal cell body [GO:0043025]; spliceosomal complex [GO:0005681]	catalytic step 2 spliceosome [GO:0071013]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; spliceosomal complex [GO:0005681]	mRNA binding [GO:0003729]; RNA binding [GO:0003723]	G-rich strand telomeric DNA binding [GO:0098505]; identical protein binding [GO:0042802]; miRNA binding [GO:0035198]; mRNA binding [GO:0003729]; pre-mRNA binding [GO:0036002]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; single-stranded DNA binding [GO:0003697]; single-stranded RNA binding [GO:0003727]; telomeric repeat-containing RNA binding [GO:0061752]
d4cq6c__d4h6ae1__1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; stromule [GO:0010319]; allene-oxide cyclase activity [GO:0046423]; jasmonic acid biosynthetic process [GO:0009695]; response to cold [GO:0009409]	allene-oxide cyclase activity [GO:0046423]; jasmonic acid biosynthetic process [GO:0009695]	jasmonic acid biosynthetic process [GO:0009695]; response to cold [GO:0009409]	jasmonic acid biosynthetic process [GO:0009695]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; stromule [GO:0010319]		allene-oxide cyclase activity [GO:0046423]	allene-oxide cyclase activity [GO:0046423]
d4cq7c__d4h6bj___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; stromule [GO:0010319]; allene-oxide cyclase activity [GO:0046423]; jasmonic acid biosynthetic process [GO:0009695]; response to cold [GO:0009409]	allene-oxide cyclase activity [GO:0046423]; jasmonic acid biosynthetic process [GO:0009695]	jasmonic acid biosynthetic process [GO:0009695]; response to cold [GO:0009409]	jasmonic acid biosynthetic process [GO:0009695]	chloroplast [GO:0009507]; chloroplast envelope [GO:0009941]; chloroplast stroma [GO:0009570]; chloroplast thylakoid membrane [GO:0009535]; cytosol [GO:0005829]; stromule [GO:0010319]		allene-oxide cyclase activity [GO:0046423]	allene-oxide cyclase activity [GO:0046423]
d4cqha2_d3notc2__1			Deinococcus-Thermus	Proteobacteria	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]; detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]	detection of visible light [GO:0009584]; osmosensory signaling via phosphorelay pathway [GO:0007234]; protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; phosphorelay response regulator activity [GO:0000156]; phosphorelay sensor kinase activity [GO:0000155]; photoreceptor activity [GO:0009881]; protein kinase activator activity [GO:0030295]
d4cqmf1_d3sjua___1	Metazoa		Chordata	Actinobacteria	mitochondrial envelope [GO:0005740]; mitochondrial matrix [GO:0005759]; plasma membrane [GO:0005886]; 3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0047025]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; NADH binding [GO:0070404]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; quinone binding [GO:0048038]; testosterone dehydrogenase (NAD+) activity [GO:0047035]; androgen metabolic process [GO:0008209]; estrogen biosynthetic process [GO:0006703]; fatty acid biosynthetic process [GO:0006633]; fatty-acyl-CoA biosynthetic process [GO:0046949]; oxidation-reduction process [GO:0055114]; protein heterotetramerization [GO:0051290]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]	androgen metabolic process [GO:0008209]; estrogen biosynthetic process [GO:0006703]; fatty acid biosynthetic process [GO:0006633]; fatty-acyl-CoA biosynthetic process [GO:0046949]; oxidation-reduction process [GO:0055114]; protein heterotetramerization [GO:0051290]		mitochondrial envelope [GO:0005740]; mitochondrial matrix [GO:0005759]; plasma membrane [GO:0005886]		3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857]; 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity [GO:0047025]; estradiol 17-beta-dehydrogenase activity [GO:0004303]; NADH binding [GO:0070404]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; quinone binding [GO:0048038]; testosterone dehydrogenase (NAD+) activity [GO:0047035]	nucleotide binding [GO:0000166]; oxidoreductase activity [GO:0016491]
d4cqva1_d2rfta___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4cqvc1_d2wr1a1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; sialate O-acetylesterase activity [GO:0001681]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]; sialate O-acetylesterase activity [GO:0001681]
d4cqve1_d4fiub1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4cqwa1_d4wstg1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4cqwc1_d4wa1b1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4cqwc1_d4wsrf1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4cqxa1_d4june1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4cqxc__d3ubna___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4cqxe1_d3eyme___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4cqye1_d1flcc1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; sialate O-acetylesterase activity [GO:0001681]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]; sialate O-acetylesterase activity [GO:0001681]
d4cqza__d5t6sg___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]; metal ion binding [GO:0046872]
d4cr24__d5bxnq___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d4cr26__d4qv0v___1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d4cr2h2_d2h1lc___1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]; ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; autophagy [GO:0006914]; B cell lineage commitment [GO:0002326]; base-excision repair [GO:0006284]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; regulation of transcription, DNA-templated [GO:0006355]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	autophagy [GO:0006914]; base-excision repair [GO:0006284]; B cell lineage commitment [GO:0002326]; bone marrow development [GO:0048539]; cardiac septum morphogenesis [GO:0060411]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular protein localization [GO:0034613]; cellular response to actinomycin D [GO:0072717]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose starvation [GO:0042149]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; cellular response to UV-C [GO:0071494]; cerebellum development [GO:0021549]; chromatin assembly [GO:0031497]; circadian behavior [GO:0048512]; cytokine-mediated signaling pathway [GO:0019221]; determination of adult lifespan [GO:0008340]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; entrainment of circadian clock by photoperiod [GO:0043153]; ER overload response [GO:0006983]; gastrulation [GO:0007369]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; interferon-gamma-mediated signaling pathway [GO:0060333]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to hypoxia [GO:1990144]; in utero embryonic development [GO:0001701]; mitochondrial DNA repair [GO:0043504]; mitotic cell cycle arrest [GO:0071850]; mitotic G1 DNA damage checkpoint [GO:0031571]; mRNA transcription [GO:0009299]; multicellular organism development [GO:0007275]; multicellular organism growth [GO:0035264]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glucose catabolic process to lactate via pyruvate [GO:1904024]; negative regulation of helicase activity [GO:0051097]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of proteolysis [GO:0045861]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron apoptotic process [GO:0051402]; nucleotide-excision repair [GO:0006289]; oligodendrocyte apoptotic process [GO:0097252]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell aging [GO:0090343]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of gene expression [GO:0010628]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of pri-miRNA transcription by RNA polymerase II [GO:1902895]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of programmed necrotic cell death [GO:0062100]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein-containing complex assembly [GO:0065003]; protein deubiquitination [GO:0016579]; protein homotetramerization [GO:0051289]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein tetramerization [GO:0051262]; Ras protein signal transduction [GO:0007265]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle G2/M phase transition [GO:1902749]; regulation of cellular senescence [GO:2000772]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of fibroblast apoptotic process [GO:2000269]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; regulation of intracellular pH [GO:0051453]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of tissue remodeling [GO:0034103]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; release of cytochrome c from mitochondria [GO:0001836]; replicative senescence [GO:0090399]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to caffeine [GO:0031000]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to retinoic acid [GO:0032526]; response to salt stress [GO:0009651]; response to UV-B [GO:0010224]; response to vitamin B3 [GO:0033552]; response to X-ray [GO:0010165]; RNA polymerase II preinitiation complex assembly [GO:0051123]; rRNA transcription [GO:0009303]; signal transduction by p53 class mediator [GO:0072331]; somitogenesis [GO:0001756]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell proliferation involved in immune response [GO:0002309]; transforming growth factor beta receptor signaling pathway [GO:0007179]; viral process [GO:0016032]; wound healing [GO:0042060]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; nuclear chromatin [GO:0000790]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PML body [GO:0016605]; protein-containing complex [GO:0032991]; replication fork [GO:0005657]; RNA polymerase II transcription factor complex [GO:0090575]; site of double-strand break [GO:0035861]; transcription factor complex [GO:0005667]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	ATP binding [GO:0005524]; chaperone binding [GO:0051087]; chromatin binding [GO:0003682]; copper ion binding [GO:0005507]; core promoter sequence-specific DNA binding [GO:0001046]; disordered domain specific binding [GO:0097718]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enzyme binding [GO:0019899]; histone acetyltransferase binding [GO:0035035]; histone deacetylase binding [GO:0042826]; histone deacetylase regulator activity [GO:0035033]; identical protein binding [GO:0042802]; MDM2/MDM4 family protein binding [GO:0097371]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; promoter-specific chromatin binding [GO:1990841]; protease binding [GO:0002020]; protein C-terminus binding [GO:0008022]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; protein N-terminus binding [GO:0047485]; protein phosphatase 2A binding [GO:0051721]; protein phosphatase binding [GO:0019903]; protein self-association [GO:0043621]; receptor tyrosine kinase binding [GO:0030971]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II transcription factor binding [GO:0001085]; TFIID-class transcription factor complex binding [GO:0001094]; transcription cofactor binding [GO:0001221]; transcription factor binding [GO:0008134]; transcription regulatory region DNA binding [GO:0044212]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]
d4cr2l2_d1oe0b___1	Fungi	Metazoa	Ascomycota	Arthropoda	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]; DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	ATP binding [GO:0005524]; deoxynucleoside kinase activity [GO:0019136]; kinase activity [GO:0016301]; thymidine kinase activity [GO:0004797]
d4cr2o1_d4cr2q1__1	Fungi	Fungi	Ascomycota	Ascomycota	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]
d4cr2p1_d4lctd1__1	Fungi	Viridiplantae	Ascomycota	Streptophyta	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	COP9 signalosome [GO:0008180]; cytosol [GO:0005829]; embryo development ending in seed dormancy [GO:0009793]; hyperosmotic response [GO:0006972]; protein deneddylation [GO:0000338]; red, far-red light phototransduction [GO:0009585]; response to absence of light [GO:0009646]; response to salt stress [GO:0009651]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	embryo development ending in seed dormancy [GO:0009793]; hyperosmotic response [GO:0006972]; protein deneddylation [GO:0000338]; red, far-red light phototransduction [GO:0009585]; response to absence of light [GO:0009646]; response to salt stress [GO:0009651]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	COP9 signalosome [GO:0008180]; cytosol [GO:0005829]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	
d4cr2s1_d1qz2c1__1	Fungi	Metazoa	Ascomycota	Chordata	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]; ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]; androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein-containing complex localization [GO:0031503]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein-containing complex localization [GO:0031503]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	axonal growth cone [GO:0044295]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; microtubule [GO:0005874]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; protein-containing complex [GO:0032991]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	ATP binding [GO:0005524]; copper-dependent protein binding [GO:0032767]; FK506 binding [GO:0005528]; glucocorticoid receptor binding [GO:0035259]; GTP binding [GO:0005525]; heat shock protein binding [GO:0031072]; peptidyl-prolyl cis-trans isomerase activity [GO:0003755]; phosphoprotein binding [GO:0051219]; protein binding, bridging [GO:0030674]; RNA binding [GO:0003723]; tau protein binding [GO:0048156]
d4cr2t1_d3txma1__1	Fungi	Metazoa	Ascomycota	Arthropoda	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]; endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]; proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; proteasome complex [GO:0000502]; proteasome regulatory particle [GO:0005838]; proteasome regulatory particle, lid subcomplex [GO:0008541]; structural molecule activity [GO:0005198]; circadian rhythm [GO:0007623]; proteasome assembly [GO:0043248]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; Toll signaling pathway [GO:0008063]; ubiquitin-dependent protein catabolic process [GO:0006511]	proteasomal protein catabolic process [GO:0010498]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	circadian rhythm [GO:0007623]; proteasome assembly [GO:0043248]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; Toll signaling pathway [GO:0008063]; ubiquitin-dependent protein catabolic process [GO:0006511]	cytoplasm [GO:0005737]; mitochondrion [GO:0005739]; nuclear outer membrane-endoplasmic reticulum membrane network [GO:0042175]; nucleus [GO:0005634]; proteasome core complex [GO:0005839]; proteasome core complex, alpha-subunit complex [GO:0019773]; proteasome storage granule [GO:0034515]	cytosol [GO:0005829]; nucleoplasm [GO:0005654]; proteasome complex [GO:0000502]; proteasome regulatory particle [GO:0005838]; proteasome regulatory particle, lid subcomplex [GO:0008541]	endopeptidase activity [GO:0004175]; threonine-type endopeptidase activity [GO:0004298]	structural molecule activity [GO:0005198]
d4cr5a__d3e16b___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; sodium channel regulator activity [GO:0017080]; cornification [GO:0070268]; positive regulation of sodium ion transport [GO:0010765]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	cornification [GO:0070268]; positive regulation of sodium ion transport [GO:0010765]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase activity [GO:0004252]; serine-type peptidase activity [GO:0008236]; sodium channel regulator activity [GO:0017080]
d4cr9a__d1nu7.1__1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]; calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]; acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	acute-phase response [GO:0006953]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cytolysis by host of symbiont cells [GO:0051838]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; G protein-coupled receptor signaling pathway [GO:0007186]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of lipid kinase activity [GO:0090218]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway [GO:1900738]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of complement activation [GO:0030449]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to wounding [GO:0009611]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	blood microparticle [GO:0072562]; cell [GO:0005623]; endoplasmic reticulum lumen [GO:0005788]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; Golgi lumen [GO:0005796]; plasma membrane [GO:0005886]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047]; growth factor activity [GO:0008083]; heparin binding [GO:0008201]; lipopolysaccharide binding [GO:0001530]; serine-type endopeptidase activity [GO:0004252]; signaling receptor binding [GO:0005102]; thrombospondin receptor activity [GO:0070053]
d4crba__d3aasa___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]; endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]; digestion [GO:0007586]; proteolysis [GO:0006508]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	digestion [GO:0007586]; proteolysis [GO:0006508]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	extracellular space [GO:0005615]; serine protease inhibitor complex [GO:0097180]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	endopeptidase activity [GO:0004175]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; serine-type endopeptidase activity [GO:0004252]; serpin family protein binding [GO:0097655]
d4crba__d5gj4b___1	Metazoa		Chordata		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA helicase activity [GO:0003724]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; induction by virus of host autophagy [GO:0039520]; suppression by virus of host STAT1 activity [GO:0039563]; suppression by virus of host STAT2 activity [GO:0039564]; suppression by virus of host TYK2 activity [GO:0039574]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062]	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; GTP binding [GO:0005525]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; mRNA (guanine-N7-)-methyltransferase activity [GO:0004482]; mRNA (nucleoside-2'-O-)-methyltransferase activity [GO:0004483]; protein dimerization activity [GO:0046983]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; serine-type endopeptidase activity [GO:0004252]; structural molecule activity [GO:0005198]
d4crta2_d2igna2__1	Metazoa	Fungi	Chordata	Basidiomycota	integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]; dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]	dopamine catabolic process [GO:0042420]; hydrogen peroxide biosynthetic process [GO:0050665]; negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; substantia nigra development [GO:0021762]		integral component of membrane [GO:0016021]; mitochondrial envelope [GO:0005740]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]		electron transfer activity [GO:0009055]; flavin adenine dinucleotide binding [GO:0050660]; primary amine oxidase activity [GO:0008131]; protein homodimerization activity [GO:0042803]	flavin adenine dinucleotide binding [GO:0050660]; pyranose oxidase activity [GO:0050233]
d4crwb__d2jj1j2__1	Metazoa	Metazoa	Chordata	Chordata	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]; ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]; ATP synthesis coupled proton transport [GO:0015986]	cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	ATP synthesis coupled proton transport [GO:0015986]	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]	mitochondrial proton-transporting ATP synthase complex [GO:0005753]; plasma membrane [GO:0005886]; proton-transporting ATP synthase complex, catalytic core F(1) [GO:0045261]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]	ADP binding [GO:0043531]; ATP binding [GO:0005524]; proton-transporting ATP synthase activity, rotational mechanism [GO:0046933]
d4crxa2_d1kbua2__1					DNA binding [GO:0003677]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]	DNA binding [GO:0003677]; DNA integration [GO:0015074]; DNA recombination [GO:0006310]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]	DNA integration [GO:0015074]; DNA recombination [GO:0006310]			DNA binding [GO:0003677]	DNA binding [GO:0003677]
d4cs5a2_d1b8ha1__1	Metazoa		Arthropoda		nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]; bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	bidirectional double-stranded viral DNA replication [GO:0039686]; DNA replication [GO:0006260]	nucleus [GO:0005634]		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; metal ion binding [GO:0046872]; nucleotide binding [GO:0000166]
d4cs5b2_d3d1fb1__1	Metazoa		Arthropoda	Proteobacteria	nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]; 3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]; cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	cellular response to DNA damage stimulus [GO:0006974]; DNA strand elongation involved in DNA replication [GO:0006271]	nucleus [GO:0005634]	cytosol [GO:0005829]; DNA polymerase III complex [GO:0009360]	DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	3'-5' exonuclease activity [GO:0008408]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; identical protein binding [GO:0042802]
d4cs5c1_d1b77a2__1	Metazoa		Arthropoda		nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]; DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275]	DNA replication [GO:0006260]; viral DNA genome replication [GO:0039693]	nucleus [GO:0005634]		DNA binding [GO:0003677]; DNA polymerase processivity factor activity [GO:0030337]	
d4csia__d2r0hd___1	Fungi	Fungi	Ascomycota	Basidiomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	cell wall [GO:0005618]; extracellular region [GO:0005576]; carbohydrate binding [GO:0030246]	cellulose catabolic process [GO:0030245]		extracellular region [GO:0005576]	cell wall [GO:0005618]; extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	carbohydrate binding [GO:0030246]
d4cspa2_d3pava2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]; detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]	nitrogen compound metabolic process [GO:0006807]	detoxification of copper ion [GO:0010273]; response to copper ion [GO:0046688]		outer membrane-bounded periplasmic space [GO:0030288]; periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; ferroxidase activity [GO:0004322]; oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [GO:0016682]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [GO:0016724]
d4cspf1_d2afnb2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]	nitrogen compound metabolic process [GO:0006807]	denitrification pathway [GO:0019333]; nitrate assimilation [GO:0042128]		periplasmic space [GO:0042597]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d4csza1_d1jvoc___1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	periplasmic space [GO:0042597]; plasma membrane [GO:0005886]; copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]; oxidation-reduction process [GO:0055114]	nitrogen compound metabolic process [GO:0006807]	oxidation-reduction process [GO:0055114]		periplasmic space [GO:0042597]; plasma membrane [GO:0005886]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; electron transfer activity [GO:0009055]; identical protein binding [GO:0042802]; transition metal ion binding [GO:0046914]; zinc ion binding [GO:0008270]
d4csza2_d1kbvd2__1			Proteobacteria	Proteobacteria	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	cell outer membrane [GO:0009279]; copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]; nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]	nitrogen compound metabolic process [GO:0006807]		cell outer membrane [GO:0009279]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]	copper ion binding [GO:0005507]; nitrite reductase (NO-forming) activity [GO:0050421]
d4ct4b1_d1s1mb2__1	Metazoa		Chordata	Proteobacteria	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	cytosol [GO:0005829]; ATP binding [GO:0005524]; CTP synthase activity [GO:0003883]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; 'de novo' CTP biosynthetic process [GO:0044210]; CTP biosynthetic process [GO:0006241]; glutamine metabolic process [GO:0006541]; pyrimidine nucleobase biosynthetic process [GO:0019856]	cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	'de novo' CTP biosynthetic process [GO:0044210]; CTP biosynthetic process [GO:0006241]; glutamine metabolic process [GO:0006541]; pyrimidine nucleobase biosynthetic process [GO:0019856]	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]	cytosol [GO:0005829]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]	ATP binding [GO:0005524]; CTP synthase activity [GO:0003883]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d4ct4d1_d3f3yb___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	cytosol [GO:0005829]; bile-salt sulfotransferase activity [GO:0047704]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]; 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; bile acid catabolic process [GO:0030573]; ethanol catabolic process [GO:0006068]; lipid catabolic process [GO:0016042]; regulation of lipid metabolic process [GO:0019216]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]	cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; bile acid catabolic process [GO:0030573]; ethanol catabolic process [GO:0006068]; lipid catabolic process [GO:0016042]; regulation of lipid metabolic process [GO:0019216]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]	cytosol [GO:0005829]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]	bile-salt sulfotransferase activity [GO:0047704]; steroid sulfotransferase activity [GO:0050294]; sulfotransferase activity [GO:0008146]
d4ct4d1_d4uj3a___1	Metazoa	Metazoa	Chordata	Chordata	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; nucleus [GO:0005634]; identical protein binding [GO:0042802]; Rab guanyl-nucleotide exchange factor activity [GO:0017112]; ciliary basal body-plasma membrane docking [GO:0097711]; cilium assembly [GO:0060271]; Golgi to plasma membrane transport [GO:0006893]; protein localization to organelle [GO:0033365]; protein targeting to membrane [GO:0006612]	cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	ciliary basal body-plasma membrane docking [GO:0097711]; cilium assembly [GO:0060271]; Golgi to plasma membrane transport [GO:0006893]; protein localization to organelle [GO:0033365]; protein targeting to membrane [GO:0006612]	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]	centrosome [GO:0005813]; ciliary basal body [GO:0036064]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; nucleus [GO:0005634]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]	identical protein binding [GO:0042802]; Rab guanyl-nucleotide exchange factor activity [GO:0017112]
d4ct5b2_d3vx4d___1	Metazoa		Chordata	Firmicutes	cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]; ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]; cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]	integral component of membrane [GO:0016021]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; ATPase-coupled bacteriocin transmembrane transporter activity [GO:0043214]; cysteine-type peptidase activity [GO:0008234]	cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; negative regulation of neuron differentiation [GO:0045665]; spermatid differentiation [GO:0048515]; stem cell population maintenance [GO:0019827]; stress granule assembly [GO:0034063]; viral RNA genome packaging [GO:0019074]		cell-cell adherens junction [GO:0005913]; chromatoid body [GO:0033391]; concave side of sperm head [GO:0061830]; cytoplasm [GO:0005737]; cytoplasmic ribonucleoprotein granule [GO:0036464]; cytoplasmic stress granule [GO:0010494]; cytosol [GO:0005829]; heterochromatin [GO:0000792]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; nucleus [GO:0005634]; outer dense fiber [GO:0001520]; P-body [GO:0000932]; perinuclear region of cytoplasm [GO:0048471]; RISC complex [GO:0016442]; sperm annulus [GO:0097227]	integral component of membrane [GO:0016021]	ATP binding [GO:0005524]; cadherin binding [GO:0045296]; helicase activity [GO:0004386]; mRNA binding [GO:0003729]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724]	ATPase activity [GO:0016887]; ATPase-coupled bacteriocin transmembrane transporter activity [GO:0043214]; ATP binding [GO:0005524]; cysteine-type peptidase activity [GO:0008234]
d4cteb__d3biwf1__1		Metazoa	Bacteroidetes	Chordata	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]; carbohydrate metabolic process [GO:0005975]	cell junction [GO:0030054]; cell projection [GO:0042995]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; vesicle [GO:0031982]; acetylcholine receptor binding [GO:0033130]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]; adult behavior [GO:0030534]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; learning [GO:0007612]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuromuscular process controlling balance [GO:0050885]; neurotransmitter secretion [GO:0007269]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein heterotetramerization [GO:0051290]; regulation of grooming behavior [GO:2000821]; synapse assembly [GO:0007416]; vesicle docking involved in exocytosis [GO:0006904]	carbohydrate metabolic process [GO:0005975]	adult behavior [GO:0030534]; cell adhesion [GO:0007155]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; learning [GO:0007612]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuromuscular process controlling balance [GO:0050885]; neurotransmitter secretion [GO:0007269]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; prepulse inhibition [GO:0060134]; presynapse assembly [GO:0099054]; protein heterotetramerization [GO:0051290]; regulation of grooming behavior [GO:2000821]; synapse assembly [GO:0007416]; vesicle docking involved in exocytosis [GO:0006904]		cell junction [GO:0030054]; cell projection [GO:0042995]; cell surface [GO:0009986]; endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; neuronal cell body [GO:0043025]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; vesicle [GO:0031982]	carbohydrate binding [GO:0030246]; glucan endo-1,3-beta-D-glucosidase activity [GO:0042973]; metal ion binding [GO:0046872]	acetylcholine receptor binding [GO:0033130]; calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509]; cell adhesion molecule binding [GO:0050839]; neuroligin family protein binding [GO:0097109]
d4ctha__d5jmya___1	Metazoa	Metazoa	Chordata	Chordata	axon [GO:0030424]; brush border [GO:0005903]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; cardiolipin binding [GO:1901612]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; oligopeptidase activity [GO:0070012]; peptide binding [GO:0042277]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; aging [GO:0007568]; amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; learning or memory [GO:0007611]; lung development [GO:0030324]; neuropeptide processing [GO:0061837]; neutrophil degranulation [GO:0043312]; peptide metabolic process [GO:0006518]; placenta development [GO:0001890]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neurogenesis [GO:0050769]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	axon [GO:0030424]; brush border [GO:0005903]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuron projection terminus [GO:0044306]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; cardiolipin binding [GO:1901612]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; oligopeptidase activity [GO:0070012]; peptide binding [GO:0042277]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; aging [GO:0007568]; amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; learning or memory [GO:0007611]; lung development [GO:0030324]; neuropeptide processing [GO:0061837]; neutrophil degranulation [GO:0043312]; peptide metabolic process [GO:0006518]; placenta development [GO:0001890]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neurogenesis [GO:0050769]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	aging [GO:0007568]; amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; learning or memory [GO:0007611]; lung development [GO:0030324]; neuropeptide processing [GO:0061837]; neutrophil degranulation [GO:0043312]; peptide metabolic process [GO:0006518]; placenta development [GO:0001890]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neurogenesis [GO:0050769]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	aging [GO:0007568]; amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; learning or memory [GO:0007611]; lung development [GO:0030324]; neuropeptide processing [GO:0061837]; neutrophil degranulation [GO:0043312]; peptide metabolic process [GO:0006518]; placenta development [GO:0001890]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neurogenesis [GO:0050769]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	axon [GO:0030424]; brush border [GO:0005903]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	axon [GO:0030424]; brush border [GO:0005903]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]	cardiolipin binding [GO:1901612]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; oligopeptidase activity [GO:0070012]; peptide binding [GO:0042277]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]	cardiolipin binding [GO:1901612]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; oligopeptidase activity [GO:0070012]; peptide binding [GO:0042277]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]
d4cuqa1_d5fe9b___1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]; cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of centriole replication [GO:0046600]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein acetylation [GO:0006473]; protein deubiquitination [GO:0016579]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	nucleus [GO:0005634]	A band [GO:0031672]; actomyosin [GO:0042641]; Ada2/Gcn5/Ada3 transcription activator complex [GO:0005671]; centrosome [GO:0005813]; I band [GO:0031674]; kinetochore [GO:0000776]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; PCAF complex [GO:0000125]; protein-containing complex [GO:0032991]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]	acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; cyclin-dependent protein serine/threonine kinase inhibitor activity [GO:0004861]; diamine N-acetyltransferase activity [GO:0004145]; histone acetyltransferase activity [GO:0004402]; histone deacetylase binding [GO:0042826]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; protein kinase binding [GO:0019901]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription coactivator activity [GO:0003713]; transcription coregulator activity [GO:0003712]; transcription factor binding [GO:0008134]
d4cura1_d5lpkg___1	Metazoa	Metazoa	Chordata	Chordata	nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]; acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	chromatin remodeling [GO:0006338]; regulation of transcription by RNA polymerase II [GO:0006357]	animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell differentiation [GO:0030183]; behavioral defense response [GO:0002209]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; circadian rhythm [GO:0007623]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone H2B acetylation [GO:0043969]; histone H4 acetylation [GO:0043967]; internal peptidyl-lysine acetylation [GO:0018393]; internal protein amino acid acetylation [GO:0006475]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; learning or memory [GO:0007611]; lung development [GO:0030324]; macrophage derived foam cell differentiation [GO:0010742]; megakaryocyte development [GO:0035855]; multicellular organism growth [GO:0035264]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine butyrylation [GO:0140067]; peptidyl-lysine crotonylation [GO:0140066]; peptidyl-lysine propionylation [GO:0061921]; platelet formation [GO:0030220]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein binding [GO:0032092]; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1905636]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of tubulin deacetylation [GO:0090043]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; skeletal muscle tissue development [GO:0007519]; somitogenesis [GO:0001756]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; swimming [GO:0036268]; thigmotaxis [GO:0001966]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	nucleus [GO:0005634]	chromosome [GO:0005694]; cytosol [GO:0005829]; histone acetyltransferase complex [GO:0000123]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-DNA complex [GO:0032993]; transcription factor complex [GO:0005667]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]	acetyltransferase activity [GO:0016407]; activating transcription factor binding [GO:0033613]; androgen receptor binding [GO:0050681]; beta-catenin binding [GO:0008013]; chromatin binding [GO:0003682]; chromatin DNA binding [GO:0031490]; damaged DNA binding [GO:0003684]; DNA binding [GO:0003677]; histone acetyltransferase activity [GO:0004402]; histone butyryltransferase activity [GO:0140069]; histone crotonyltransferase activity [GO:0140068]; lysine N-acetyltransferase activity, acting on acetyl phosphate as donor [GO:0004468]; NF-kappaB binding [GO:0051059]; nuclear hormone receptor binding [GO:0035257]; p53 binding [GO:0002039]; peptide butyryltransferase activity [GO:0140065]; peptide-lysine-N-acetyltransferase activity [GO:0061733]; pre-mRNA intronic binding [GO:0097157]; protein C-terminus binding [GO:0008022]; protein propionyltransferase activity [GO:0061920]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; RNA polymerase II transcription factor binding [GO:0001085]; STAT family protein binding [GO:0097677]; tau protein binding [GO:0048156]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; transferase activity, transferring acyl groups [GO:0016746]; zinc ion binding [GO:0008270]
d4cvca__d4maeb___1				Verrucomicrobia	metal ion binding [GO:0046872]	membrane [GO:0016020]; 2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; ethanol:cytochrome c oxidoreductase activity [GO:0052935]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]				membrane [GO:0016020]	metal ion binding [GO:0046872]	2-chloroethanol cytochrome-c oxidoreductase activity [GO:0052932]; calcium ion binding [GO:0005509]; ethanol:cytochrome c oxidoreductase activity [GO:0052935]; ethanol cytochrome-c oxidoreductase activity [GO:0052931]; methanol ferricytochrome-c oxidoreductase activity [GO:0052930]
d4cvia__d5v53a2__1	Fungi		Ascomycota	Proteobacteria	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]	catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d4cvpa1_d5da5t1__1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]		cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	metal ion binding [GO:0046872]
d4cvqb__d4uhma___1			Proteobacteria	Proteobacteria	cytoplasm [GO:0005737]; L-alanine:2-oxoglutarate aminotransferase activity [GO:0004021]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]; alanine biosynthetic process [GO:0006523]; cellular response to DNA damage stimulus [GO:0006974]; D-alanine biosynthetic process [GO:0030632]; L-alanine biosynthetic process from pyruvate [GO:0019272]; response to antibiotic [GO:0046677]	metal ion binding [GO:0046872]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	alanine biosynthetic process [GO:0006523]; cellular response to DNA damage stimulus [GO:0006974]; D-alanine biosynthetic process [GO:0030632]; L-alanine biosynthetic process from pyruvate [GO:0019272]; response to antibiotic [GO:0046677]		cytoplasm [GO:0005737]		L-alanine:2-oxoglutarate aminotransferase activity [GO:0004021]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]	metal ion binding [GO:0046872]; pyridoxal phosphate binding [GO:0030170]; transaminase activity [GO:0008483]
d4cvsa1_d3r2ra___1			Proteobacteria	Proteobacteria	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4cvta1_d2jd8k___1			Proteobacteria	Euryarchaeota	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; cytosol [GO:0005829]; membrane [GO:0016020]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; heme binding [GO:0020037]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; oxidoreductase activity [GO:0016491]	ferric iron binding [GO:0008199]
d4cvwc__d2n81a___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	serine-type endopeptidase inhibitor activity [GO:0004867]	lipid binding [GO:0008289]; lipid transport [GO:0006869]		lipid transport [GO:0006869]			serine-type endopeptidase inhibitor activity [GO:0004867]	lipid binding [GO:0008289]
d4cvwc__d3ceeb___1	Viridiplantae		Streptophyta		serine-type endopeptidase inhibitor activity [GO:0004867]						serine-type endopeptidase inhibitor activity [GO:0004867]	
d4cvwd__d1jtba___1	Viridiplantae	Viridiplantae	Streptophyta	Streptophyta	serine-type endopeptidase inhibitor activity [GO:0004867]	lipid binding [GO:0008289]; lipid transport [GO:0006869]		lipid transport [GO:0006869]			serine-type endopeptidase inhibitor activity [GO:0004867]	lipid binding [GO:0008289]
d4cw0a2_d1vayh2__1	Fungi		Ascomycota		peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]		peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	
d4cw2a2_d4ntke___1	Fungi		Ascomycota	Proteobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]; queuosine biosynthetic process [GO:0008616]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	queuosine biosynthetic process [GO:0008616]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	6-carboxy-5,6,7,8-tetrahydropterin synthase activity [GO:0070497]; identical protein binding [GO:0042802]; zinc ion binding [GO:0008270]
d4cw3a1_d5ll1f2__1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d4cw3a2_d1is7j___1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]; negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein heterooligomerization [GO:0051291]; protein-containing complex assembly [GO:0065003]; regulation of nitric oxide biosynthetic process [GO:0045428]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; protein-containing complex assembly [GO:0065003]; protein heterooligomerization [GO:0051291]; regulation of nitric oxide biosynthetic process [GO:0045428]	peroxisome [GO:0005777]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; melanosome [GO:0042470]; nuclear membrane [GO:0031965]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]	urate oxidase activity [GO:0004846]	amino acid binding [GO:0016597]; enzyme binding [GO:0019899]; enzyme inhibitor activity [GO:0004857]; GTP cyclohydrolase binding [GO:0044549]; GTP-dependent protein binding [GO:0030742]
d4cw9a__d1xw5a2__1		Metazoa		Chordata	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]; enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]; cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cellular detoxification of nitrogen compound [GO:0070458]; cellular response to caffeine [GO:0071313]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; linoleic acid metabolic process [GO:0043651]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; nitrobenzene metabolic process [GO:0018916]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014809]; relaxation of cardiac muscle [GO:0055119]; xenobiotic catabolic process [GO:0042178]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; intercellular bridge [GO:0045171]; sarcoplasmic reticulum [GO:0016529]	protein disulfide oxidoreductase activity [GO:0015035]	enzyme binding [GO:0019899]; glutathione binding [GO:0043295]; glutathione peroxidase activity [GO:0004602]; glutathione transferase activity [GO:0004364]; protein homodimerization activity [GO:0042803]; signaling receptor binding [GO:0005102]
d4cw9b1_d1iyia2__1		Metazoa		Chordata	cell [GO:0005623]; protein disulfide oxidoreductase activity [GO:0015035]; cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]; cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	cyclooxygenase pathway [GO:0019371]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; locomotory behavior [GO:0007626]; negative regulation of male germ cell proliferation [GO:2000255]; prostaglandin metabolic process [GO:0006693]; signal transduction [GO:0007165]	cell [GO:0005623]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]	protein disulfide oxidoreductase activity [GO:0015035]	calcium ion binding [GO:0005509]; glutathione transferase activity [GO:0004364]; magnesium ion binding [GO:0000287]; prostaglandin-D synthase activity [GO:0004667]; protein homodimerization activity [GO:0042803]
d4cwac__d3rodc___1		Metazoa	Apicomplexa	Chordata	cytosol [GO:0005829]; spermidine synthase activity [GO:0004766]; polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; nicotinamide N-methyltransferase activity [GO:0008112]; pyridine N-methyltransferase activity [GO:0030760]; animal organ regeneration [GO:0031100]; methylation [GO:0032259]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]	polyamine biosynthetic process [GO:0006596]; spermidine biosynthetic process [GO:0008295]	animal organ regeneration [GO:0031100]; methylation [GO:0032259]; NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]	cytosol [GO:0005829]	cytoplasm [GO:0005737]; cytosol [GO:0005829]	spermidine synthase activity [GO:0004766]	nicotinamide N-methyltransferase activity [GO:0008112]; pyridine N-methyltransferase activity [GO:0030760]
d4cx9a__d5xzia___1			Proteobacteria	Proteobacteria	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	periplasmic space [GO:0042597]; electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]			periplasmic space [GO:0042597]	periplasmic space [GO:0042597]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]	electron transfer activity [GO:0009055]; heme binding [GO:0020037]; iron ion binding [GO:0005506]
d4cxad2_d4ogrk1__1	Metazoa	Metazoa	Chordata	Chordata	cyclin K-CDK12 complex [GO:0002944]; cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]; mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	ELL-EAF complex [GO:0032783]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription elongation factor complex [GO:0008023]; transcriptionally active chromatin [GO:0035327]; DNA-binding transcription factor activity [GO:0003700]; double-stranded DNA binding [GO:0003690]; spermatid development [GO:0007286]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	spermatid development [GO:0007286]; transcription by RNA polymerase II [GO:0006366]; transcription elongation from RNA polymerase II promoter [GO:0006368]	cyclin-dependent protein kinase holoenzyme complex [GO:0000307]; cyclin K-CDK12 complex [GO:0002944]; nuclear chromatin [GO:0000790]; nuclear cyclin-dependent protein kinase holoenzyme complex [GO:0019908]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]	ELL-EAF complex [GO:0032783]; fibrillar center [GO:0001650]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcriptionally active chromatin [GO:0035327]; transcription elongation factor complex [GO:0008023]	ATP binding [GO:0005524]; cyclin binding [GO:0030332]; cyclin-dependent protein serine/threonine kinase activity [GO:0004693]; protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901]; RNA polymerase II CTD heptapeptide repeat kinase activity [GO:0008353]	DNA-binding transcription factor activity [GO:0003700]; double-stranded DNA binding [GO:0003690]
d4cxrb__d1bt4a1__1			Actinobacteria	Firmicutes	cytoplasm [GO:0005737]; adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]; biotin biosynthetic process [GO:0009102]	cytoplasm [GO:0005737]; O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]; L-serine biosynthetic process [GO:0006564]	biotin biosynthetic process [GO:0009102]	L-serine biosynthetic process [GO:0006564]	cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	adenosylmethionine-8-amino-7-oxononanoate transaminase activity [GO:0004015]; pyridoxal phosphate binding [GO:0030170]	O-phospho-L-serine:2-oxoglutarate aminotransferase activity [GO:0004648]; pyridoxal phosphate binding [GO:0030170]
d4cy9a1_d1oqbe___1		Viridiplantae	Actinobacteria	Streptophyta	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	chloroplast [GO:0009507]; acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]; fatty acid biosynthetic process [GO:0006633]	cellular iron ion homeostasis [GO:0006879]	fatty acid biosynthetic process [GO:0006633]	cell [GO:0005623]	chloroplast [GO:0009507]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	acyl-[acyl-carrier-protein] desaturase activity [GO:0045300]; metal ion binding [GO:0046872]; stearoyl-[acp] desaturase activity [GO:0102786]
d4cyaa__d2xkqj___1			Actinobacteria	Firmicutes	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]; cytoplasm [GO:0005737]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d4cybf__d3rgdx___1		Metazoa	Actinobacteria	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4cybg__d2z90c___1			Actinobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d4cybk__d3is7g___1			Actinobacteria	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4cybl__d5ww9a___1			Actinobacteria	Actinobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]; DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]; cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cellular iron ion homeostasis [GO:0006879]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]	DNA binding [GO:0003677]; ferric iron binding [GO:0008199]; oxidoreductase activity, oxidizing metal ions [GO:0016722]
d4cywa__d3bt6a___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	endocytosis involved in viral entry into host cell [GO:0075509]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4cywa__d4wsse1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4cyza__d4wste1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4cyzc__d2wr7c1__1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4cyze__d4wsxm___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	viral envelope [GO:0019031]; host cell surface receptor binding [GO:0046789]; fusion of virus membrane with host plasma membrane [GO:0019064]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	fusion of virus membrane with host plasma membrane [GO:0019064]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	viral envelope [GO:0019031]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4cz1c__d2b0aa1__1			Firmicutes	Euryarchaeota	arylformamidase activity [GO:0004061]; formamidase activity [GO:0004328]; zinc ion binding [GO:0008270]; anthranilate metabolic process [GO:0043420]; tryptophan catabolic process to kynurenine [GO:0019441]	arylformamidase activity [GO:0004061]; tryptophan catabolic process to kynurenine [GO:0019441]	anthranilate metabolic process [GO:0043420]; tryptophan catabolic process to kynurenine [GO:0019441]	tryptophan catabolic process to kynurenine [GO:0019441]			arylformamidase activity [GO:0004061]; formamidase activity [GO:0004328]; zinc ion binding [GO:0008270]	arylformamidase activity [GO:0004061]
d4czjb2_d4h0yb2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calcium-dependent protein binding [GO:0048306]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]; actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	actin filament bundle assembly [GO:0051017]; actin filament polymerization [GO:0030041]; mesenchyme migration [GO:0090131]; positive regulation of actin-dependent ATPase activity [GO:1904623]; positive regulation of gene expression [GO:0010628]; skeletal muscle fiber development [GO:0048741]; skeletal muscle thin filament assembly [GO:0030240]	cytoplasm [GO:0005737]	actin filament [GO:0005884]; actin filament bundle [GO:0032432]; cell body [GO:0044297]; cytoplasm [GO:0005737]; filamentous actin [GO:0031941]; filopodium [GO:0030175]; lamellipodium [GO:0030027]; skeletal muscle myofibril [GO:0098723]; stress fiber [GO:0001725]; striated muscle thin filament [GO:0005865]	ATP binding [GO:0005524]	actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; myosin heavy chain binding [GO:0032036]; protein domain specific binding [GO:0019904]; titin binding [GO:0031432]; tropomyosin binding [GO:0005523]; troponin I binding [GO:0031013]
d4czla2_d3hm8a2__1		Metazoa	Proteobacteria	Chordata	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]; ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]; canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glycolytic process [GO:0006096]; neutrophil degranulation [GO:0043312]	cytoplasm [GO:0005737]	cell [GO:0005623]; cytosol [GO:0005829]; extracellular region [GO:0005576]; ficolin-1-rich granule lumen [GO:1904813]; secretory granule lumen [GO:0034774]	ATP binding [GO:0005524]	ATP binding [GO:0005524]; fructokinase activity [GO:0008865]; glucokinase activity [GO:0004340]; glucose binding [GO:0005536]; hexokinase activity [GO:0004396]; mannokinase activity [GO:0019158]
d4czmb2_d1x9jc2__1			Proteobacteria	Thermotogae	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]	cytoplasm [GO:0005737]; ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]	cell morphogenesis [GO:0000902]; regulation of cell shape [GO:0008360]		cytoplasm [GO:0005737]	cytoplasm [GO:0005737]	ATP binding [GO:0005524]	ATP binding [GO:0005524]; butyrate kinase activity [GO:0047761]
d4czna__d5sxwb2__1				Proteobacteria		catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]		hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]				catalase activity [GO:0004096]; heme binding [GO:0020037]; metal ion binding [GO:0046872]
d4czoa__d1dj5a___1		Fungi		Ascomycota		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d4czoa__d1pxxd1__1		Metazoa		Chordata		caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]; enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]; aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]		aging [GO:0007568]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; brown fat cell differentiation [GO:0050873]; cellular response to ATP [GO:0071318]; cellular response to fluid shear stress [GO:0071498]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to lead ion [GO:0071284]; cellular response to mechanical stimulus [GO:0071260]; cellular response to non-ionic osmotic stress [GO:0071471]; cellular response to UV [GO:0034644]; cyclooxygenase pathway [GO:0019371]; decidualization [GO:0046697]; embryo implantation [GO:0007566]; hair cycle [GO:0042633]; inflammatory response [GO:0006954]; keratinocyte differentiation [GO:0030216]; learning [GO:0007612]; maintenance of permeability of blood-brain barrier [GO:0035633]; memory [GO:0007613]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood vessel diameter [GO:0097756]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress [GO:1902219]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; ovulation [GO:0030728]; positive regulation of apoptotic process [GO:0043065]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of fibroblast growth factor production [GO:0090271]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of platelet-derived growth factor production [GO:0090362]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transforming growth factor beta production [GO:0071636]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; regulation of cell population proliferation [GO:0042127]; regulation of neuroinflammatory response [GO:0150077]; response to angiotensin [GO:1990776]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to manganese ion [GO:0010042]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to vitamin D [GO:0033280]; sensory perception of pain [GO:0019233]		caveola [GO:0005901]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; neuron projection [GO:0043005]; protein-containing complex [GO:0032991]		enzyme binding [GO:0019899]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702]; peroxidase activity [GO:0004601]; prostaglandin-endoperoxide synthase activity [GO:0004666]; protein homodimerization activity [GO:0042803]
d4czqa__d4jb4a___1		Fungi		Ascomycota		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]; cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		cellular response to oxidative stress [GO:0034599]; hydrogen peroxide catabolic process [GO:0042744]; response to reactive oxygen species [GO:0000302]		mitochondrial intermembrane space [GO:0005758]; mitochondrial matrix [GO:0005759]; mitochondrion [GO:0005739]		cytochrome-c peroxidase activity [GO:0004130]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d4czra__d1h5ea___1		Viridiplantae		Streptophyta		extracellular region [GO:0005576]; vacuole [GO:0005773]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]		hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]		extracellular region [GO:0005576]; vacuole [GO:0005773]		heme binding [GO:0020037]; metal ion binding [GO:0046872]; peroxidase activity [GO:0004601]
d4d00a__d3eyka___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4d00c__d4jtvi___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4d00e__d5th0c___1			Negarnaviricota	Negarnaviricota	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]; host cell surface receptor binding [GO:0046789]; clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	clathrin-dependent endocytosis of virus by host cell [GO:0075512]; fusion of virus membrane with host endosome membrane [GO:0039654]; fusion of virus membrane with host plasma membrane [GO:0019064]; viral budding from plasma membrane [GO:0046761]; virion attachment to host cell [GO:0019062]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036]	host cell surface receptor binding [GO:0046789]	host cell surface receptor binding [GO:0046789]
d4d08b__d1q9md___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d4d09a__d1mkda___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]; adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; multicellular organism growth [GO:0035264]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; regulation of signaling receptor activity [GO:0010469]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	apical plasma membrane [GO:0016324]; calcium channel complex [GO:0034704]; centrosome [GO:0005813]; cytosol [GO:0005829]; membrane [GO:0016020]; plasma membrane [GO:0005886]; voltage-gated calcium channel complex [GO:0005891]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; ATPase binding [GO:0051117]; beta-2 adrenergic receptor binding [GO:0031698]; cAMP binding [GO:0030552]; drug binding [GO:0008144]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; scaffold protein binding [GO:0097110]; ubiquitin protein ligase binding [GO:0031625]
d4d09d__d3dyqa2__1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; cGMP catabolic process [GO:0046069]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of mitochondrion organization [GO:0010821]; ventricular septum development [GO:0003281]	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]	cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]	3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; calcium channel activity [GO:0005262]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; drug binding [GO:0008144]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270]	3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]
d4d0ba2_d1zhbj2__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]	cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]	protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4d0ba2_d5bxfa1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [GO:0002480]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular protein metabolic process [GO:0044267]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; iron ion homeostasis [GO:0055072]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of receptor binding [GO:1900121]; neutrophil degranulation [GO:0043312]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of defense response to virus by virus [GO:0050690]; regulation of immune response [GO:0050776]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; retina homeostasis [GO:0001895]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]	cell surface [GO:0009986]; cytosol [GO:0005829]; early endosome lumen [GO:0031905]; early endosome membrane [GO:0031901]; endoplasmic reticulum lumen [GO:0005788]; ER to Golgi transport vesicle membrane [GO:0012507]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; HFE-transferrin receptor complex [GO:1990712]; membrane [GO:0016020]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; recycling endosome membrane [GO:0055038]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]	protein homodimerization activity [GO:0042803]	identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4d0bb__d3q6fi1__1	Metazoa		Chordata		cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]		amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]		cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]		protein homodimerization activity [GO:0042803]	
d4d0ca1_d1plgh1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	metal ion binding [GO:0046872]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]		cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]		protein homodimerization activity [GO:0042803]	metal ion binding [GO:0046872]
d4d0ca1_d4y4hh1__1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]; adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	adaptive immune response [GO:0002250]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]	integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; T cell receptor complex [GO:0042101]	protein homodimerization activity [GO:0042803]	
d4d0cb__d1bzql___1	Metazoa	Metazoa	Chordata	Chordata	cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]	extracellular region [GO:0005576]; endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]	amyloid fibril formation [GO:1990000]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; cellular response to iron ion [GO:0071281]; cellular response to nicotine [GO:0071316]; immune response [GO:0006955]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; regulation of iron ion transport [GO:0034756]		cytosol [GO:0005829]; extracellular region [GO:0005576]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]	extracellular region [GO:0005576]	protein homodimerization activity [GO:0042803]	endonuclease activity [GO:0004519]; lyase activity [GO:0016829]; nucleic acid binding [GO:0003676]; ribonuclease activity [GO:0004540]
d4d13a1_d2yzdc2__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d4d13a1_d5m98a2__1	Fungi	Metazoa	Ascomycota	Chordata	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	protein homotetramerization [GO:0051289]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]	peroxisome [GO:0005777]	urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d4d13a2_d2yzeh2__1	Fungi		Ascomycota	Actinobacteria	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	peroxisome [GO:0005777]		urate oxidase activity [GO:0004846]	urate oxidase activity [GO:0004846]
d4d19a1_d1sqla___1	Fungi	Viridiplantae	Ascomycota	Streptophyta	peroxisome [GO:0005777]; urate oxidase activity [GO:0004846]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	cytosol [GO:0005829]; dihydroneopterin aldolase activity [GO:0004150]; folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	folic acid biosynthetic process [GO:0046656]; folic acid-containing compound metabolic process [GO:0006760]; tetrahydrofolate biosynthetic process [GO:0046654]	peroxisome [GO:0005777]	cytosol [GO:0005829]	urate oxidase activity [GO:0004846]	dihydroneopterin aldolase activity [GO:0004150]
d4d2ka1_d1ibxa1__1	Metazoa		Arthropoda	Firmicutes	postsynaptic membrane [GO:0045211]; synaptic membrane [GO:0097060]; apoptotic process [GO:0006915]; negative regulation of neuron death [GO:1901215]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]; IgG binding [GO:0019864]; pathogenesis [GO:0009405]	apoptotic process [GO:0006915]; negative regulation of neuron death [GO:1901215]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]	pathogenesis [GO:0009405]	postsynaptic membrane [GO:0045211]; synaptic membrane [GO:0097060]	cell wall [GO:0005618]; extracellular region [GO:0005576]; membrane [GO:0016020]		IgG binding [GO:0019864]
d4d3cl1_d4odvl2__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d4d3cl2_d2f8vb2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]; actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; receptor-mediated endocytosis [GO:0006898]; regulation of complement activation [GO:0030449]; regulation of immune response [GO:0050776]; retina homeostasis [GO:0001895]	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]; striated muscle myosin thick filament assembly [GO:0071688]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]	condensed nuclear chromosome [GO:0000794]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; I band [GO:0031674]; M band [GO:0031430]; sarcomere [GO:0030017]; striated muscle thin filament [GO:0005865]; Z disc [GO:0030018]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	actin filament binding [GO:0051015]; actinin binding [GO:0042805]; ATP binding [GO:0005524]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; enzyme binding [GO:0019899]; identical protein binding [GO:0042802]; muscle alpha-actinin binding [GO:0051371]; protease binding [GO:0002020]; protein kinase binding [GO:0019901]; protein self-association [GO:0043621]; protein serine/threonine kinase activity [GO:0004674]; protein tyrosine kinase activity [GO:0004713]; structural constituent of muscle [GO:0008307]; structural molecule activity conferring elasticity [GO:0097493]; telethonin binding [GO:0031433]
d4d3qb__d1i57a___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; JUN kinase phosphatase activity [GO:0008579]; MAP-kinase scaffold activity [GO:0005078]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase activator activity [GO:0030295]; protein kinase inhibitor activity [GO:0004860]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase activity [GO:0045860]; regulation of MAP kinase activity [GO:0043405]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase activity [GO:0045860]; regulation of MAP kinase activity [GO:0043405]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	JUN kinase phosphatase activity [GO:0008579]; MAP-kinase scaffold activity [GO:0005078]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase activator activity [GO:0030295]; protein kinase inhibitor activity [GO:0004860]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d4d3ra__d2cmaa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; JUN kinase phosphatase activity [GO:0008579]; MAP-kinase scaffold activity [GO:0005078]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase activator activity [GO:0030295]; protein kinase inhibitor activity [GO:0004860]; protein tyrosine phosphatase activity [GO:0004725]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase activity [GO:0045860]; regulation of MAP kinase activity [GO:0043405]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]; cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase activity [GO:0045860]; regulation of MAP kinase activity [GO:0043405]	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; cellular response to unfolded protein [GO:0034620]; endoplasmic reticulum unfolded protein response [GO:0030968]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of signal transduction [GO:0009968]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; regulation of type I interferon-mediated signaling pathway [GO:0060338]	cytoplasm [GO:0005737]	cytoplasmic side of endoplasmic reticulum membrane [GO:0098554]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; protein-containing complex [GO:0032991]; sorting endosome [GO:0097443]	JUN kinase phosphatase activity [GO:0008579]; MAP-kinase scaffold activity [GO:0005078]; mitogen-activated protein kinase kinase kinase binding [GO:0031435]; protein kinase activator activity [GO:0030295]; protein kinase inhibitor activity [GO:0004860]; protein tyrosine phosphatase activity [GO:0004725]	cadherin binding [GO:0045296]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; insulin receptor binding [GO:0005158]; protein kinase binding [GO:0019901]; protein phosphatase 2A binding [GO:0051721]; protein tyrosine phosphatase activity [GO:0004725]; receptor tyrosine kinase binding [GO:0030971]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
d4d5oa__d1z3wa___1	Fungi	Fungi	Ascomycota	Basidiomycota	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]; cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]; cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	cellulose catabolic process [GO:0030245]	extracellular region [GO:0005576]	extracellular region [GO:0005576]	cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	cellulose binding [GO:0030248]; hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553]
d4d5pa__d4yz2b1__1	Fungi		Ascomycota	Firmicutes	extracellular region [GO:0005576]; cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]; cellulose catabolic process [GO:0030245]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]; carbohydrate metabolic process [GO:0005975]	cellulose catabolic process [GO:0030245]	carbohydrate metabolic process [GO:0005975]	extracellular region [GO:0005576]		cellulose 1,4-beta-cellobiosidase activity [GO:0016162]; cellulose binding [GO:0030248]	exo-alpha-(2->3)-sialidase activity [GO:0052794]; exo-alpha-(2->6)-sialidase activity [GO:0052795]; exo-alpha-(2->8)-sialidase activity [GO:0052796]
d4d6ba1_d1b0oa___1	Metazoa	Metazoa	Chordata	Chordata	cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]; cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]; membrane organization [GO:0061024]	extracellular region [GO:0005576]; identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]	membrane organization [GO:0061024]		cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; myelin sheath [GO:0043209]	extracellular region [GO:0005576]	cholesterol binding [GO:0015485]; fatty acid binding [GO:0005504]	identical protein binding [GO:0042802]; long-chain fatty acid binding [GO:0036041]; retinol binding [GO:0019841]
d4d6ca1_d3n2ea1__1				Proteobacteria		cytosol [GO:0005829]; ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]; aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]; shikimate metabolic process [GO:0019632]		cytosol [GO:0005829]		ATP binding [GO:0005524]; magnesium ion binding [GO:0000287]; shikimate kinase activity [GO:0004765]
d4d6da1_d4mitb___1						plasma membrane [GO:0005886]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; small GTPase mediated signal transduction [GO:0007264]		small GTPase mediated signal transduction [GO:0007264]		plasma membrane [GO:0005886]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]
d4d6ha1_d6b8ba___1				Proteobacteria		ATP-binding cassette (ABC) transporter complex [GO:0043190]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity [GO:0016887]; lipopolysaccharide floppase activity [GO:0015437]; protein-containing complex binding [GO:0044877]; lipopolysaccharide transport [GO:0015920]; transmembrane transport [GO:0055085]		lipopolysaccharide transport [GO:0015920]; transmembrane transport [GO:0055085]		ATP-binding cassette (ABC) transporter complex [GO:0043190]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886]		ATPase activity [GO:0016887]; ATP binding [GO:0005524]; lipopolysaccharide floppase activity [GO:0015437]; protein-containing complex binding [GO:0044877]
d4d6ja1_d3lawb___1		Metazoa		Chordata		autophagosome membrane [GO:0000421]; cell [GO:0005623]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extrinsic component of lysosome membrane [GO:0032419]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome membrane [GO:0033162]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; phagophore assembly site membrane [GO:0034045]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; GDP binding [GO:0019003]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; retromer complex binding [GO:1905394]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; autophagosome assembly [GO:0000045]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; endosome to lysosome transport [GO:0008333]; epidermal growth factor catabolic process [GO:0007174]; intracellular protein transport [GO:0006886]; lipid catabolic process [GO:0016042]; lipophagy [GO:0061724]; multi-organism intracellular transport [GO:1902583]; negative regulation of exosomal secretion [GO:1903542]; negative regulation of intralumenal vesicle formation [GO:1905366]; neutrophil degranulation [GO:0043312]; phagosome acidification [GO:0090383]; phagosome maturation [GO:0090382]; phagosome-lysosome fusion [GO:0090385]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of viral process [GO:0048524]; protein targeting to lysosome [GO:0006622]; protein to membrane docking [GO:0022615]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; retrograde transport, endosome to Golgi [GO:0042147]; viral release from host cell [GO:0019076]		antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; autophagosome assembly [GO:0000045]; early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; endosome to lysosome transport [GO:0008333]; epidermal growth factor catabolic process [GO:0007174]; intracellular protein transport [GO:0006886]; lipid catabolic process [GO:0016042]; lipophagy [GO:0061724]; multi-organism intracellular transport [GO:1902583]; negative regulation of exosomal secretion [GO:1903542]; negative regulation of intralumenal vesicle formation [GO:1905366]; neutrophil degranulation [GO:0043312]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385]; phagosome maturation [GO:0090382]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of viral process [GO:0048524]; protein targeting to lysosome [GO:0006622]; protein to membrane docking [GO:0022615]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; retrograde transport, endosome to Golgi [GO:0042147]; viral release from host cell [GO:0019076]		autophagosome membrane [GO:0000421]; cell [GO:0005623]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; extracellular exosome [GO:0070062]; extrinsic component of lysosome membrane [GO:0032419]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lipid droplet [GO:0005811]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; melanosome membrane [GO:0033162]; phagocytic vesicle [GO:0045335]; phagocytic vesicle membrane [GO:0030670]; phagophore assembly site membrane [GO:0034045]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]		GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; retromer complex binding [GO:1905394]
d4d6ja1_d3wxma1__1				Crenarchaeota		cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; translation elongation factor activity [GO:0003746]				cytoplasm [GO:0005737]		GTPase activity [GO:0003924]; GTP binding [GO:0005525]; translation elongation factor activity [GO:0003746]
d4d6va1_d3pvub___1	Fungi	Metazoa	Basidiomycota	Chordata		G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]		adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; cell population proliferation [GO:0008283]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to prostaglandin E stimulus [GO:0071380]; G protein-coupled receptor signaling pathway [GO:0007186]		G-protein beta/gamma-subunit complex [GO:0031680]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]		G-protein beta-subunit binding [GO:0031681]; GTPase activity [GO:0003924]
d4d6xa__d1dcma___1			Proteobacteria	Proteobacteria	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]; DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; positive regulation of transcription, DNA-templated [GO:0045893]		cytoplasm [GO:0005737]; protein-DNA complex [GO:0032993]	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	DNA-binding transcription activator activity [GO:0001216]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]
d4d6xd__d1ny5a1__1			Proteobacteria	Aquificae	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	ATP binding [GO:0005524]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]
d4d6ya__d1nxwa___1			Proteobacteria	Firmicutes	ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]			ATP binding [GO:0005524]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; transcription factor binding [GO:0008134]	DNA binding [GO:0003677]; metal ion binding [GO:0046872]
d4d7fa__d2sgde___1	Metazoa	Metazoa	Chordata	Chordata	extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]; heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	extracellular region [GO:0005576]; serine-type endopeptidase inhibitor activity [GO:0004867]	blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]		extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; membrane [GO:0016020]; plasma membrane [GO:0005886]	extracellular region [GO:0005576]	heparin binding [GO:0008201]; identical protein binding [GO:0042802]; serine-type aminopeptidase activity [GO:0070009]; serine-type endopeptidase activity [GO:0004252]	serine-type endopeptidase inhibitor activity [GO:0004867]
d4d7ha__d3eaib___1		Metazoa	Firmicutes	Chordata	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric-oxide synthase activity [GO:0004517]; nitric oxide biosynthetic process [GO:0006809]	cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]; actin binding [GO:0003779]; arginine binding [GO:0034618]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; cAMP-dependent protein kinase regulator activity [GO:0008603]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; nitric-oxide synthase binding [GO:0050998]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tetrahydrobiopterin binding [GO:0034617]; arginine catabolic process [GO:0006527]; cellular response to cytokine stimulus [GO:0071345]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; circadian rhythm [GO:0007623]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; prostaglandin secretion [GO:0032310]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]	nitric oxide biosynthetic process [GO:0006809]	arginine catabolic process [GO:0006527]; cellular response to cytokine stimulus [GO:0071345]; cellular response to drug [GO:0035690]; cellular response to interferon-gamma [GO:0071346]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; circadian rhythm [GO:0007623]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; interleukin-6 secretion [GO:0072604]; interleukin-8 secretion [GO:0072606]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of killing of cells of other organism [GO:0051712]; prostaglandin secretion [GO:0032310]; regulation of cell population proliferation [GO:0042127]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of insulin secretion [GO:0050796]; response to bacterium [GO:0009617]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; superoxide metabolic process [GO:0006801]		cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; vesicle membrane [GO:0012506]	heme binding [GO:0020037]; metal ion binding [GO:0046872]; nitric-oxide synthase activity [GO:0004517]	actin binding [GO:0003779]; arginine binding [GO:0034618]; beta-catenin binding [GO:0008013]; cadherin binding [GO:0045296]; calmodulin binding [GO:0005516]; cAMP-dependent protein kinase regulator activity [GO:0008603]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; Hsp90 protein binding [GO:0051879]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; NADPH-hemoprotein reductase activity [GO:0003958]; nitric-oxide synthase activity [GO:0004517]; nitric-oxide synthase binding [GO:0050998]; oxidoreductase activity [GO:0016491]; protein homodimerization activity [GO:0042803]; protein kinase binding [GO:0019901]; tetrahydrobiopterin binding [GO:0034617]
d4d7lb__d2iema___1			Actinobacteria	Proteobacteria	peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; cellular protein modification process [GO:0006464]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; L-methionine-(S)-S-oxide reductase activity [GO:0036456]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]; cellular protein modification process [GO:0006464]; cellular response to oxidative stress [GO:0034599]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	cellular protein modification process [GO:0006464]	cellular protein modification process [GO:0006464]; cellular response to oxidative stress [GO:0034599]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]		cytoplasm [GO:0005737]; cytosol [GO:0005829]	peptide-methionine (S)-S-oxide reductase activity [GO:0008113]	L-methionine-(S)-S-oxide reductase activity [GO:0036456]; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [GO:0016671]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113]
d4d7na1_d3br3b1__1			Proteobacteria	Firmicutes	DNA binding [GO:0003677]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]	negative regulation of transcription, DNA-templated [GO:0045892]; response to antibiotic [GO:0046677]	negative regulation of transcription, DNA-templated [GO:0045892]			DNA binding [GO:0003677]; metal ion binding [GO:0046872]	DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d4d7sa__d4i01b1__1			Spirochaetes	Proteobacteria	integral component of membrane [GO:0016021]; nucleotide binding [GO:0000166]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]; cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]; carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]		carbon catabolite repression of transcription [GO:0045013]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	integral component of membrane [GO:0016021]	cytosol [GO:0005829]; protein-DNA complex [GO:0032993]	nucleotide binding [GO:0000166]	cAMP binding [GO:0030552]; DNA-binding transcription factor activity [GO:0003700]; identical protein binding [GO:0042802]; sequence-specific DNA binding [GO:0043565]
d4d7sb__d4a2uc1__1			Spirochaetes	Actinobacteria	integral component of membrane [GO:0016021]; nucleotide binding [GO:0000166]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]		negative regulation of transcription, DNA-templated [GO:0045892]; pathogenesis [GO:0009405]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	integral component of membrane [GO:0016021]	cell wall [GO:0005618]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	nucleotide binding [GO:0000166]	cAMP binding [GO:0030552]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]
d4d86a1_d5cb5l___1	Metazoa		Chordata	Proteobacteria	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; protein ADP-ribosylase activity [GO:1990404]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]; negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]	negative regulation of endoribonuclease activity [GO:0060702]; purine nucleoside metabolic process [GO:0042278]; regulation of single-species biofilm formation on inanimate substrate [GO:1900231]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; protein ADP-ribosylase activity [GO:1990404]	endoribonuclease inhibitor activity [GO:0060698]; enzyme binding [GO:0019899]; O-acetyl-ADP-ribose deacetylase activity [GO:0061463]; purine nucleoside binding [GO:0001883]
d4d86a2_d5fuda1__1	Metazoa		Chordata	Firmicutes	cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; protein ADP-ribosylase activity [GO:1990404]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]	nucleotide binding [GO:0000166]	innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein ADP-ribosylation [GO:0006471]; protein mono-ADP-ribosylation [GO:0140289]; protein poly-ADP-ribosylation [GO:0070212]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886]		enzyme binding [GO:0019899]; NAD+ ADP-ribosyltransferase activity [GO:0003950]; NAD+ binding [GO:0070403]; protein ADP-ribosylase activity [GO:1990404]	nucleotide binding [GO:0000166]
d4d8fc1_d1xvgd___1			Chlamydiae	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	ribonucleoside-diphosphate reductase complex [GO:0005971]		metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d4d8fc1_d3is7q___1			Chlamydiae	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4d8fd1_d1fzib___1			Chlamydiae	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	ribonucleoside-diphosphate reductase complex [GO:0005971]		metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d4d8ga1_d2xjog___1			Chlamydiae	Firmicutes	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cell [GO:0005623]; cytoplasm [GO:0005737]; ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]; cellular iron ion homeostasis [GO:0006879]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular iron ion homeostasis [GO:0006879]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cell [GO:0005623]; cytoplasm [GO:0005737]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	ferric iron binding [GO:0008199]; oxidoreductase activity [GO:0016491]
d4d8ga1_d3pvtc1__1			Chlamydiae	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cytosol [GO:0005829]; phenylacetate catabolic process [GO:0010124]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	phenylacetate catabolic process [GO:0010124]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cytosol [GO:0005829]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	
d4d8gb1_d1piua___1			Chlamydiae	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; nucleobase-containing small molecule interconversion [GO:0015949]	ribonucleoside-diphosphate reductase complex [GO:0005971]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; ribonucleoside-diphosphate reductase complex [GO:0005971]	metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]
d4d8gc1_d3rnab___1			Chlamydiae	Proteobacteria	ribonucleoside-diphosphate reductase complex [GO:0005971]; metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]; cellular aromatic compound metabolic process [GO:0006725]	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	cellular aromatic compound metabolic process [GO:0006725]	ribonucleoside-diphosphate reductase complex [GO:0005971]		metal ion binding [GO:0046872]; ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [GO:0004748]	metal ion binding [GO:0046872]; monooxygenase activity [GO:0004497]
d4d96b__d1pwha___1		Metazoa	Proteobacteria	Chordata	D-cysteine desulfhydrase activity [GO:0019148]; D-amino acid metabolic process [GO:0046416]	cytoplasm [GO:0005737]; L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]; gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]	D-amino acid metabolic process [GO:0046416]	gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; response to amino acid [GO:0043200]; response to cobalamin [GO:0033590]; response to nutrient levels [GO:0031667]; threonine catabolic process [GO:0006567]		cytoplasm [GO:0005737]	D-cysteine desulfhydrase activity [GO:0019148]	L-serine ammonia-lyase activity [GO:0003941]; L-threonine ammonia-lyase activity [GO:0004794]; protein dimerization activity [GO:0046983]; pyridoxal phosphate binding [GO:0030170]
d4d98a__d1vhjf___1			Firmicutes	Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	purine-nucleoside phosphorylase activity [GO:0004731]; nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]	purine nucleoside metabolic process [GO:0042278]	nucleobase-containing compound metabolic process [GO:0006139]; purine nucleoside metabolic process [GO:0042278]			purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d4d98b__d1nw4a___1			Firmicutes	Apicomplexa	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]	purine nucleoside metabolic process [GO:0042278]	nucleoside metabolic process [GO:0009116]			purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d4d9cc__d3zeia___1			Proteobacteria	Actinobacteria	D-cysteine desulfhydrase activity [GO:0019148]; D-amino acid metabolic process [GO:0046416]	cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	D-amino acid metabolic process [GO:0046416]	cysteine biosynthetic process from serine [GO:0006535]		cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular region [GO:0005576]	D-cysteine desulfhydrase activity [GO:0019148]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]
d4d9ea__d2c2bc___1		Viridiplantae	Proteobacteria	Streptophyta	D-cysteine desulfhydrase activity [GO:0019148]; D-amino acid metabolic process [GO:0046416]	chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]; threonine biosynthetic process [GO:0009088]	D-amino acid metabolic process [GO:0046416]	threonine biosynthetic process [GO:0009088]		chloroplast [GO:0009507]; chloroplast stroma [GO:0009570]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]	D-cysteine desulfhydrase activity [GO:0019148]	pyridoxal phosphate binding [GO:0030170]; threonine synthase activity [GO:0004795]
d4d9fa__d2jc3b___1			Proteobacteria	Proteobacteria	D-cysteine desulfhydrase activity [GO:0019148]; D-amino acid metabolic process [GO:0046416]	cytoplasm [GO:0005737]; cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]; cysteine biosynthetic process from serine [GO:0006535]	D-amino acid metabolic process [GO:0046416]	cysteine biosynthetic process from serine [GO:0006535]		cytoplasm [GO:0005737]	D-cysteine desulfhydrase activity [GO:0019148]	cysteine synthase activity [GO:0004124]; L-cysteine desulfhydrase activity [GO:0080146]; pyridoxal phosphate binding [GO:0030170]
d4d9ll1_d2rhea___1												
d4d9ll2_d4ei5f___1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]; identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]; amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron ion [GO:0071281]; cellular response to iron(III) ion [GO:0071283]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		amyloid fibril formation [GO:1990000]; antibacterial humoral response [GO:0019731]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular defense response [GO:0006968]; cellular response to iron(III) ion [GO:0071283]; cellular response to iron ion [GO:0071281]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; learning or memory [GO:0007611]; modulation of age-related behavioral decline [GO:0090647]; multicellular organism development [GO:0007275]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of receptor binding [GO:1900121]; positive regulation of cellular senescence [GO:2000774]; positive regulation of ferrous iron binding [GO:1904434]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor binding [GO:1900122]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transferrin receptor binding [GO:1904437]; protein homotetramerization [GO:0051289]; protein refolding [GO:0042026]; regulation of erythrocyte differentiation [GO:0045646]; regulation of iron ion transport [GO:0034756]; regulation of membrane depolarization [GO:0003254]; response to cadmium ion [GO:0046686]; response to molecule of bacterial origin [GO:0002237]; T cell differentiation in thymus [GO:0033077]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; extracellular space [GO:0005615]; Golgi apparatus [GO:0005794]; HFE-transferrin receptor complex [GO:1990712]; MHC class I peptide loading complex [GO:0042824]; MHC class I protein complex [GO:0042612]; phagocytic vesicle membrane [GO:0030670]; plasma membrane [GO:0005886]		identical protein binding [GO:0042802]; protein homodimerization activity [GO:0042803]
d4d9lm1_d2rcjf1__1		Metazoa		Chordata								
d4d9lm2_d1fpth1__1		Metazoa		Chordata		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		antibody-dependent cellular cytotoxicity [GO:0001788]; antigen processing and presentation [GO:0019882]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; immunoglobulin mediated immune response [GO:0016064]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; positive regulation of endocytosis [GO:0045807]; positive regulation of immune response [GO:0050778]; positive regulation of phagocytosis [GO:0050766]; positive regulation of type I hypersensitivity [GO:0001812]; positive regulation of type IIa hypersensitivity [GO:0001798]; regulation of proteolysis [GO:0030162]		cytosol [GO:0005829]; external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4d9ln1_d1jhkl2__1		Metazoa		Chordata								
d4d9lo2_d1lo0x1__1		Metazoa		Chordata		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]		external side of plasma membrane [GO:0009897]; immunoglobulin complex, circulating [GO:0042571]; plasma membrane [GO:0005886]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]
d4d9qb__d3mmga___1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	helical viral capsid [GO:0019029]; ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]; RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	RNA-protein covalent cross-linking [GO:0018144]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	helical viral capsid [GO:0019029]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; helicase activity [GO:0004386]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; serine-type peptidase activity [GO:0008236]; structural molecule activity [GO:0005198]
d4d9qd1_d1n8za2__1	Metazoa	Metazoa	Chordata	Chordata	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]; ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]; cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]	cell surface receptor signaling pathway [GO:0007166]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; enzyme linked receptor protein signaling pathway [GO:0007167]; ERBB2 signaling pathway [GO:0038128]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; motor neuron axon guidance [GO:0008045]; myelination [GO:0042552]; negative regulation of ERBB signaling pathway [GO:1901185]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; neuromuscular junction development [GO:0007528]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]; regulation of cell motility [GO:2000145]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of microtubule-based process [GO:0032886]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing [GO:0042060]	blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]	apical plasma membrane [GO:0016324]; basal plasma membrane [GO:0009925]; basolateral plasma membrane [GO:0016323]; cytosol [GO:0005829]; early endosome [GO:0005769]; endosome membrane [GO:0010008]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; myelin sheath [GO:0043209]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; receptor complex [GO:0043235]	antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	ATP binding [GO:0005524]; ErbB-3 class receptor binding [GO:0043125]; identical protein binding [GO:0042802]; protein C-terminus binding [GO:0008022]; protein dimerization activity [GO:0046983]; protein heterodimerization activity [GO:0046982]; protein phosphatase binding [GO:0019903]; protein tyrosine kinase activity [GO:0004713]; RNA polymerase I core binding [GO:0001042]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane signaling receptor activity [GO:0004888]
d4d9ql1_d1q9ka1__1	Metazoa		Chordata		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]; antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]; B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		B cell receptor signaling pathway [GO:0050853]; complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; cytokine-mediated signaling pathway [GO:0019221]; defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of B cell activation [GO:0050871]; regulation of complement activation [GO:0030449]		blood microparticle [GO:0072562]; external side of plasma membrane [GO:0009897]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; immunoglobulin complex, circulating [GO:0042571]		antigen binding [GO:0003823]; immunoglobulin receptor binding [GO:0034987]	
d4da8a__d4glja___1			Firmicutes		purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]; L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]	purine nucleoside metabolic process [GO:0042278]	L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166]			purine-nucleoside phosphorylase activity [GO:0004731]	S-methyl-5-thioadenosine phosphorylase activity [GO:0017061]
d4daea__d4wkca___1			Firmicutes	Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	cytosol [GO:0005829]; adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]; L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]	purine nucleoside metabolic process [GO:0042278]	L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284]; nucleoside catabolic process [GO:0009164]; toxic metabolite repair [GO:0110052]		cytosol [GO:0005829]	purine-nucleoside phosphorylase activity [GO:0004731]	adenosylhomocysteine nucleosidase activity [GO:0008782]; identical protein binding [GO:0042802]; methylthioadenosine nucleosidase activity [GO:0008930]
d4damd__d1pvod2__1			Actinobacteria	Proteobacteria	single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]	cytosol [GO:0005829]; membrane [GO:0016020]; ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]; DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]	DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]	DNA-templated transcription, termination [GO:0006353]; transcription, DNA-templated [GO:0006351]		cytosol [GO:0005829]; membrane [GO:0016020]	single-stranded DNA binding [GO:0003697]	ATP binding [GO:0005524]; helicase activity [GO:0004386]; identical protein binding [GO:0042802]; RNA binding [GO:0003723]; RNA-dependent ATPase activity [GO:0008186]
d4dame1_d1gd7d___1			Actinobacteria	Deinococcus-Thermus	single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]	tRNA binding [GO:0000049]	DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]				single-stranded DNA binding [GO:0003697]	tRNA binding [GO:0000049]
d4damf__d2uxcq1__1			Actinobacteria	Deinococcus-Thermus	single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]	ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]	DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]	translation [GO:0006412]		ribosome [GO:0005840]	single-stranded DNA binding [GO:0003697]	rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]
d4dami__d2qalq1__1			Actinobacteria		single-stranded DNA binding [GO:0003697]; DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]		DNA replication [GO:0006260]; positive regulation of helicase activity [GO:0051096]				single-stranded DNA binding [GO:0003697]	
d4danb__d5mx6c___1			Firmicutes	Proteobacteria	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	purine-nucleoside phosphorylase activity [GO:0004731]; purine nucleoside metabolic process [GO:0042278]	purine nucleoside metabolic process [GO:0042278]	purine nucleoside metabolic process [GO:0042278]			purine-nucleoside phosphorylase activity [GO:0004731]	purine-nucleoside phosphorylase activity [GO:0004731]
d4dasa__d2fzfb___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]		cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; oxidoreductase activity [GO:0016491]
d4dasf__d2jd8r___1	Metazoa		Chordata	Euryarchaeota	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]
d4dasi__d3wnwa___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	immune response [GO:0006955]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of fibroblast proliferation [GO:0048147]	cell [GO:0005623]	autolysosome [GO:0044754]; cell [GO:0005623]; cytoplasm [GO:0005737]; endocytic vesicle lumen [GO:0071682]; extracellular region [GO:0005576]; mitochondrion [GO:0005739]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d4dasi__d5d8xr___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	intracellular sequestering of iron ion [GO:0006880]; iron ion transport [GO:0006826]	cell [GO:0005623]	cell [GO:0005623]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]
d4dasj__d1fz7c___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]; cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular aromatic compound metabolic process [GO:0006725]; one-carbon metabolic process [GO:0006730]	cell [GO:0005623]		ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	metal ion binding [GO:0046872]; methane monooxygenase activity [GO:0015049]
d4dasj__d2fg8f___1	Metazoa	Metazoa	Chordata	Chordata	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]; ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]; cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cellular iron ion homeostasis [GO:0006879]; intracellular sequestering of iron ion [GO:0006880]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; neutrophil degranulation [GO:0043312]	cell [GO:0005623]	autolysosome [GO:0044754]; azurophil granule lumen [GO:0035578]; cell [GO:0005623]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; intracellular ferritin complex [GO:0008043]; membrane [GO:0016020]	ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]	ferric iron binding [GO:0008199]; ferrous iron binding [GO:0008198]; ferroxidase activity [GO:0004322]; identical protein binding [GO:0042802]; iron ion binding [GO:0005506]
d4dask__d4to9k___1	Metazoa		Chordata	Proteobacteria	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxidase activity [GO:0004322]; cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	cell [GO:0005623]; ferric iron binding [GO:0008199]; ferroxid